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Sample records for bow direction reversal

  1. Articulated coordination of the right arm underlies control of bow parameters and quick bow reversals in skilled cello bowing.

    PubMed

    Verrel, Julius; Woollacott, Marjorie; Lindenberger, Ulman

    2014-01-01

    Stringed instrument bowing is a complex coordinative motor skill acquired though years of intense practice. We apply a novel "freezing" analysis to investigate how movement at different joints contributes to bow transport (movement amplitude), stabilization of bow parameters (angle, velocity) during bow movements, and quick reversals of bow direction (acceleration amplitude). Participants were ten advanced or professional cellists (19-32 years, at least 10 years of practice) and ten age-matched novice players. Arm and bow movements were recorded using 3D motion capture. To assess how performance depends on articulated use of the right arm, actual data were compared to surrogate data, generated by artificially removing movement at ("freezing") individual joints in measured arm movements. This analysis showed that both elbow and shoulder significantly contribute to bow transport in experts, while only the shoulder contributed to bow transport in novices. Moreover, experts showed more strongly increased variability of bow parameters and reduced acceleration amplitudes at bow reversals for surrogate compared to actual movement data. This indicates that movement across joints was organized to reduce bow variability and achieve quick bow reversals. Corresponding effects were less pronounced or absent in the novices, in particular for the wrist and elbow. Our results demonstrate the importance of articulated use of the right arm and clarify the contribution of different joints in experts' bowing performance. Moreover, they support theories of motor control and learning that propose exploitation of biomechanical degrees of freedom, in particular of distal joints, as a critical component in skilled motor performance.

  2. UWB Bi-directional Bow-tie antenna loaded by rings

    NASA Astrophysics Data System (ADS)

    Peng, Lin; Sun, Kai; Xie, Ji-yang; Qiu, Yu-jie; Jiang, Xing

    2016-07-01

    Performances of bow-tie antennae can be improved by loading a ring. Specially, the distorted radiation patterns of the reference bow-tie antenna (RBA) at high frequencies become less distorted when a ring is added. That is due to the disciplined current flows trained by the ring. Furthermore, when more rings are loaded, which act as reflectors, higher directivities are obtained and, patterns become bi-directional. Antennae with no ring (RBA), one ring, two rings (three cases), three rings, and four rings are investigated. Research find that loading more rings means better directivity. The directivity of the RBA varies from 2.29 dB to 3.66 dB for the frequency band from 2.5 to 7.5 GHz while the directivity for the four-ring-loaded case varies from 4.27 dB to 7.61 dB in that frequency band.

  3. Pattern Switchable Antenna System Using Inkjet-Printed Directional Bow-Tie for Bi-Direction Sensing Applications.

    PubMed

    Eom, Seung-Hyun; Seo, Yunsik; Lim, Sungjoon

    2015-01-01

    In this paper, we propose a paper-based pattern switchable antenna system using inkjet-printing technology for bi-direction sensor applications. The proposed antenna system is composed of two directional bow-tie antennas and a switching network. The switching network consists of a single-pole-double-throw (SPDT) switch and a balun element. A double-sided parallel-strip line (DSPSL) is employed to convert the unbalanced microstrip mode to the balanced strip mode. Two directional bow-tie antennas have different radiation patterns because of the different orientation of the reflectors and antennas. It is demonstrated from electromagnetic (EM) simulation and measurement that the radiation patterns of the proposed antenna are successfully switched by the SPDT switch.

  4. Pattern Switchable Antenna System Using Inkjet-Printed Directional Bow-Tie for Bi-Direction Sensing Applications.

    PubMed

    Eom, Seung-Hyun; Seo, Yunsik; Lim, Sungjoon

    2015-01-01

    In this paper, we propose a paper-based pattern switchable antenna system using inkjet-printing technology for bi-direction sensor applications. The proposed antenna system is composed of two directional bow-tie antennas and a switching network. The switching network consists of a single-pole-double-throw (SPDT) switch and a balun element. A double-sided parallel-strip line (DSPSL) is employed to convert the unbalanced microstrip mode to the balanced strip mode. Two directional bow-tie antennas have different radiation patterns because of the different orientation of the reflectors and antennas. It is demonstrated from electromagnetic (EM) simulation and measurement that the radiation patterns of the proposed antenna are successfully switched by the SPDT switch. PMID:26690443

  5. Pattern Switchable Antenna System Using Inkjet-Printed Directional Bow-Tie for Bi-Direction Sensing Applications

    PubMed Central

    Eom, Seung-Hyun; Seo, Yunsik; Lim, Sungjoon

    2015-01-01

    In this paper, we propose a paper-based pattern switchable antenna system using inkjet-printing technology for bi-direction sensor applications. The proposed antenna system is composed of two directional bow-tie antennas and a switching network. The switching network consists of a single-pole-double-throw (SPDT) switch and a balun element. A double-sided parallel-strip line (DSPSL) is employed to convert the unbalanced microstrip mode to the balanced strip mode. Two directional bow-tie antennas have different radiation patterns because of the different orientation of the reflectors and antennas. It is demonstrated from electromagnetic (EM) simulation and measurement that the radiation patterns of the proposed antenna are successfully switched by the SPDT switch. PMID:26690443

  6. Violin bow vibrations.

    PubMed

    Gough, Colin E

    2012-05-01

    The modal frequencies and bending mode shapes of a freely supported tapered violin bow are investigated by finite element analysis and direct measurement, with and without tensioned bow hair. Such computations are used with analytic models to model the admittance presented to the stretched bow hairs at the ends of the bow and to the string at the point of contact with the bow. Finite element computations are also used to demonstrate the influence of the lowest stick mode vibrations on the low frequency bouncing modes, when the hand-held bow is pressed against the string. The possible influence of the dynamic stick modes on the sound of the bowed instrument is briefly discussed. PMID:22559386

  7. Violin bow vibrations.

    PubMed

    Gough, Colin E

    2012-05-01

    The modal frequencies and bending mode shapes of a freely supported tapered violin bow are investigated by finite element analysis and direct measurement, with and without tensioned bow hair. Such computations are used with analytic models to model the admittance presented to the stretched bow hairs at the ends of the bow and to the string at the point of contact with the bow. Finite element computations are also used to demonstrate the influence of the lowest stick mode vibrations on the low frequency bouncing modes, when the hand-held bow is pressed against the string. The possible influence of the dynamic stick modes on the sound of the bowed instrument is briefly discussed.

  8. Directional diffusion coefficients of solar protons inside and outside the bow shock.

    NASA Technical Reports Server (NTRS)

    Verzariu, P.; Krimigis, S. M.

    1973-01-01

    The directional diffusion coefficients of low-energy (greater than or equal to 0.3 MeV) solar protons inside and outside the bow shock are examined during the solar flare event of Jan. 24, 1969. The data are derived from simultaneous observations obtained by Explorer 33 inside the magnetosheath and by Explorer 35 in the interplanetary medium. Although the gross properties of the spin-averaged intensities on a diffusion-type plot appear to be the same in both media, the directional intensities show significant variations. It is shown that directional intensities of low-energy protons can be described reasonably well by anisotropic diffusion with an associated diffusion coefficient. Directional diffusion coefficients are found to differ by a factor of as much as three among different directions in space, and from the spin-averaged diffusion coefficient. This suggests that anisotropic diffusion does indeed take place and that so called 'isotropic' diffusion coefficients derived in the past from spin-averaged intensities may actually be directional diffusion coefficients in cases where substantial anisotropies (greater than 50%) exist.

  9. Coordination in fast repetitive violin-bowing patterns.

    PubMed

    Schoonderwaldt, Erwin; Altenmüller, Eckart

    2014-01-01

    We present a study of coordination behavior in complex violin-bowing patterns involving simultaneous bow changes (reversal of bowing direction) and string crossings (changing from one string to another). Twenty-two violinists (8 advanced amateurs, 8 students with violin as major subject, and 6 elite professionals) participated in the experiment. We investigated the influence of a variety of performance conditions (specific bowing patterns, dynamic level, tempo, and transposition) and level of expertise on coordination behavior (a.o., relative phase and amplitude) and stability. It was found that the general coordination behavior was highly consistent, characterized by a systematic phase lead of bow inclination over bow velocity of about 15° (i.e., string crossings were consistently timed earlier than bow changes). Within similar conditions, a high individual consistency was found, whereas the inter-individual agreement was considerably less. Furthermore, systematic influences of performance conditions on coordination behavior and stability were found, which could be partly explained in terms of particular performance constraints. Concerning level of expertise, only subtle differences were found, the student and professional groups (higher level of expertise) showing a slightly higher stability than the amateur group (lower level of expertise). The general coordination behavior as observed in the current study showed a high agreement with perceptual preferences reported in an earlier study to similar bowing patterns, implying that complex bowing trajectories for an important part emerge from auditory-motor interaction.

  10. Coordination in fast repetitive violin-bowing patterns.

    PubMed

    Schoonderwaldt, Erwin; Altenmüller, Eckart

    2014-01-01

    We present a study of coordination behavior in complex violin-bowing patterns involving simultaneous bow changes (reversal of bowing direction) and string crossings (changing from one string to another). Twenty-two violinists (8 advanced amateurs, 8 students with violin as major subject, and 6 elite professionals) participated in the experiment. We investigated the influence of a variety of performance conditions (specific bowing patterns, dynamic level, tempo, and transposition) and level of expertise on coordination behavior (a.o., relative phase and amplitude) and stability. It was found that the general coordination behavior was highly consistent, characterized by a systematic phase lead of bow inclination over bow velocity of about 15° (i.e., string crossings were consistently timed earlier than bow changes). Within similar conditions, a high individual consistency was found, whereas the inter-individual agreement was considerably less. Furthermore, systematic influences of performance conditions on coordination behavior and stability were found, which could be partly explained in terms of particular performance constraints. Concerning level of expertise, only subtle differences were found, the student and professional groups (higher level of expertise) showing a slightly higher stability than the amateur group (lower level of expertise). The general coordination behavior as observed in the current study showed a high agreement with perceptual preferences reported in an earlier study to similar bowing patterns, implying that complex bowing trajectories for an important part emerge from auditory-motor interaction. PMID:25207542

  11. Coordination in Fast Repetitive Violin-Bowing Patterns

    PubMed Central

    Schoonderwaldt, Erwin; Altenmüller, Eckart

    2014-01-01

    We present a study of coordination behavior in complex violin-bowing patterns involving simultaneous bow changes (reversal of bowing direction) and string crossings (changing from one string to another). Twenty-two violinists (8 advanced amateurs, 8 students with violin as major subject, and 6 elite professionals) participated in the experiment. We investigated the influence of a variety of performance conditions (specific bowing patterns, dynamic level, tempo, and transposition) and level of expertise on coordination behavior (a.o., relative phase and amplitude) and stability. It was found that the general coordination behavior was highly consistent, characterized by a systematic phase lead of bow inclination over bow velocity of about 15° (i.e., string crossings were consistently timed earlier than bow changes). Within similar conditions, a high individual consistency was found, whereas the inter-individual agreement was considerably less. Furthermore, systematic influences of performance conditions on coordination behavior and stability were found, which could be partly explained in terms of particular performance constraints. Concerning level of expertise, only subtle differences were found, the student and professional groups (higher level of expertise) showing a slightly higher stability than the amateur group (lower level of expertise). The general coordination behavior as observed in the current study showed a high agreement with perceptual preferences reported in an earlier study to similar bowing patterns, implying that complex bowing trajectories for an important part emerge from auditory-motor interaction. PMID:25207542

  12. Rotation of fold axes during southerly directed thrusting, Broken Bow Uplift, Ouachita Mountains of Oklahoma

    SciTech Connect

    Yang, Qingming; Nielsen, K.C. )

    1993-02-01

    The Broken Bow Uplift has been subdivided into four large structures: Hochatown dome, Carter Mountain anticlinorium, Linson Creek synclinorium, and Cross Mountain anticlinorium. Detailed geological mapping of lower Paleozoic units in the western portion of Carter Mountain anticlinorium has revealed three fault zones from north to south: North Bee Creek fault zone (NBCFZ), South Carter Creek fault zone (SCCFZ), and Dyer Mountain fault zone (DMFZ). These fault zones separate two anticlines: Carter Mountain anticline and Brigham anticline. DMFZ is the tectonic contact between the Carter Mountain Anticlinorium and Hochatown dome to the south. The earliest folds in Hochatown dome are overturned, tight to isoclinal, subhorizontal with planar limbs and sharp hinges that trend east-west. The Carter Mountain and Brigham anticlines are interpreted to be associated with these earliest folds. As DMFZ is approached from Hochatown dome, fold axes plunge 15--20[degree] to WNW. The folds within the fault zones have been significantly rotated and plunge at 30--55[degree] to northwest or north. Within the South Carter Creek fault zone, a horse block is developed around a thick folded sequence of Arkansas Novaculite with fold hinge trending 350[degree]/50[degree]. The fold axes data clearly show concentration trending in northwest direction. However there is a scatter of data with orientations trending due north as well as to northeast. A model of earlier fold axes rotation as a result of simple shear associated with inferred southerly directed thrusting has been proposed to explain the geometric relationship described above. The best fit great circle for the rotated fold axis data has an orientation of 95[degree]/55[degree]N. This calculated plane represents the plane of flattening associated with the southerly directed thrusting.

  13. Reversal Agents for the Direct Oral Anticoagulants.

    PubMed

    Ansell, Jack E

    2016-10-01

    The vitamin K antagonists (VKAs) are associated with a significant rate of major and fatal bleeding complications. The new direct oral anticoagulants (DOACs), even though having a better bleeding profile than the VKAs, are still associated with serious bleeding. The anticoagulation induced by the VKAs can be reversed with both vitamin K and prothrombin complex concentrates, whereas the DOACs were developed without specific reversal agents. Although there is controversy around the necessity of a reversal agent, most clinicians agree that having a reversal agent for the DOACs would be beneficial. Three reversal agents are currently in development. PMID:27637309

  14. Bowed Strings

    NASA Astrophysics Data System (ADS)

    Rossing, Thomas D.; Hanson, Roger J.

    In the next eight chapters, we consider some aspects of the science of bowed string instruments, old and new. In this chapter, we present a brief discussion of bowed strings, a subject that will be developed much more thoroughly in Chap. 16. Chapters 13-15 discuss the violin, the cello, and the double bass. Chapter 17 discusses viols and other historic string instruments, and Chap. 18 discusses the Hutchins-Schelleng violin octet.

  15. 29 GHz directly modulated 980 nm vertical-cavity surface emitting lasers with bow-tie shape transverse coupled cavity

    NASA Astrophysics Data System (ADS)

    Dalir, Hamed; Koyama, Fumio

    2013-08-01

    A concept for the bandwidth enhancement of directly modulated vertical-cavity surface emitting lasers (VCSELs) using a transverse-coupled-cavity (TCC) scheme is proposed, which enables us to tailor the modulation-transfer function. A bow-tie shaped oxide aperture forms the transverse-coupled cavity resulting in optical feedback to boost the modulation speed. While the bandwidth of conventional VCSELs is 9-10 GHz, the 3 dB-bandwidth of the TCC VCSEL is increased by a factor of 3 far beyond the relaxation-oscillation frequency. The maximum bandwidth is currently limited by the photo-detector used in the experiment. Clear 36 Gbps eye opening was attained with an extinction ratio of 4 dB.

  16. Direct observation of time reversal violation

    SciTech Connect

    Bernabeu, J.

    2013-06-12

    A direct evidence for Time Reversal Violation (TRV) means an experiment that, considered by itself, clearly shows TRV independent of, and unconnected to, the results for CP Violation. No existing result before the recent BABAR experiment with entangled neutral B mesons had demonstrated TRV in this sense. There is a unique opportunity for a search of TRV with unstable particles thanks to the Einstein-Podolsky-Rosen (EPR) Entanglement between the two neutral mesons in B, and PHI, Factories. The two quantum effects of the first decay as a filtering measurement and the transfer of information to the still living partner allow performing a genuine TRV asymmetry with the exchange of 'in' and 'out' states. With four independent TRV asymmetries, BABAR observes a large deviation of T-invariance with a statistical significance of 14 standard deviations, far more than needed to declare the result as a discovery. This is the first direct observation of TRV in the time evolution of any system.

  17. Extraction of bowing parameters from violin performance combining motion capture and sensors.

    PubMed

    Schoonderwaldt, E; Demoucron, M

    2009-11-01

    A method is described for measurement of a complete set of bowing parameters in violin performance. Optical motion capture was combined with sensors for accurate measurement of the main bowing parameters (bow position, bow velocity, bow acceleration, bow-bridge distance, and bow force) as well as secondary control parameters (skewness, inclination, and tilt of the bow). In addition, other performance features (moments of on/off in bow-string contact, string played, and bowing direction) were extracted. Detailed descriptions of the calculations of the bowing parameters, features, and calibrations are given. The described system is capable of measuring all bowing parameters without disturbing the player, allowing for detailed studies of musically relevant aspects of bow control and coordination of bowing parameters in bowed-string instrument performance. PMID:19894846

  18. Extraction of bowing parameters from violin performance combining motion capture and sensors.

    PubMed

    Schoonderwaldt, E; Demoucron, M

    2009-11-01

    A method is described for measurement of a complete set of bowing parameters in violin performance. Optical motion capture was combined with sensors for accurate measurement of the main bowing parameters (bow position, bow velocity, bow acceleration, bow-bridge distance, and bow force) as well as secondary control parameters (skewness, inclination, and tilt of the bow). In addition, other performance features (moments of on/off in bow-string contact, string played, and bowing direction) were extracted. Detailed descriptions of the calculations of the bowing parameters, features, and calibrations are given. The described system is capable of measuring all bowing parameters without disturbing the player, allowing for detailed studies of musically relevant aspects of bow control and coordination of bowing parameters in bowed-string instrument performance.

  19. Earth's bow shock: Power aspects.

    NASA Astrophysics Data System (ADS)

    Sedykh, Pavel

    2012-07-01

    The process of energy transfer from the solar wind into the magnetosphere, or rather, to convecting magnetospheric plasma, appears to be rather complicated. The bow shock front is the main converter of solar wind kinetic energy into electromagnetic energy [Ponomarev, Sedykh, J. of Atm. Solar-Terr. Phys. V. 68. 2006; Ponomarev, Sedykh et al., Geomagn. and Aeron., 2009]. Solar wind undergoes significant changes in its parameters during its passing through the bow shock front. Indeed, at the bow point, when crossing the front, the magnetic field tangential component and magnetic energy density increase by factors of almost 4 and approximately 15, respectively. In describing the bow shock, we followed [Whang, 1987; Ponomarev et al., 2006]. A jump of the magnetic field tangential component when crossing the bow shock front means that the front carries an electric current. It is possible to show that electric current is diverging in this layer, that is the front is the generator of the current. Since plasma with magnetic field passes through the bow shock front, electric field arises in the front reference system. Thus, the bow shock front is a source of electric power. The direction of electric current behind the bow shock front depends on the sign of the IMF Bz-component. It is this current which sets convection in motion. Energetically, this external current is necessary for maintaining convection of plasma in the inhomogeneous system (geomagnetosphere). The generator at the bow shock front can be a sufficient source of power for supplying energy to substorm processes [Sedykh, Sun and Geosphere, 2011]. The sign of power does not depend on the IMF sign, and energy flux is always directed into the magnetosphere. The magnitude of the power is different and is realized in different regions of the magnetosphere depending on the IMF direction. When the Bz-component is negative, the electric convection field is larger, with the anticonvection field being smaller, than for

  20. The supernumerary bows of the rainbow

    NASA Astrophysics Data System (ADS)

    Adams, Peter; Ricard, Jean; Barckicke, Jean

    2016-04-01

    Everyone appreciate the mysterious beauty of a Rainbow picture. The primary bow shows red on the outer part and violet on the inner side. It is caused by light being refracted when entering a droplet of water, then reflected inside on the back of the droplet and refracted again when leaving it. The secondaty bow is seen outside the primary arc, and has the order of its colours reversed, with red on the inner side of the arc. The supernumerary bows are alternating faint bows on the inner side of the primary rainbow (and also outside the secondary rainbow). In this presentation, we will describe the present knowledge and the future perspectives A fully funded PhD Scholarship on this topic is open at the University of Granada. Picture = Contrast-enhanced photograph of a primary bow picture (prepared by Andrew Dunn).

  1. 3D model of bow shocks

    NASA Astrophysics Data System (ADS)

    Gustafsson, M.; Ravkilde, T.; Kristensen, L. E.; Cabrit, S.; Field, D.; Pineau Des Forêts, G.

    2010-04-01

    Context. Shocks produced by outflows from young stars are often observed as bow-shaped structures in which the H2 line strength and morphology are characteristic of the physical and chemical environments and the velocity of the impact. Aims: We present a 3D model of interstellar bow shocks propagating in a homogeneous molecular medium with a uniform magnetic field. The model enables us to estimate the shock conditions in observed flows. As an example, we show how the model can reproduce rovibrational H2 observations of a bow shock in OMC1. Methods: The 3D model is constructed by associating a planar shock with every point on a 3D bow skeleton. The planar shocks are modelled with a highly sophisticated chemical reaction network that is essential for predicting accurate shock widths and line emissions. The shock conditions vary along the bow surface and determine the shock type, the local thickness, and brightness of the bow shell. The motion of the cooling gas parallel to the bow surface is also considered. The bow shock can move at an arbitrary inclination to the magnetic field and to the observer, and we model the projected morphology and radial velocity distribution in the plane-of-sky. Results: The morphology of a bow shock is highly dependent on the orientation of the magnetic field and the inclination of the flow. Bow shocks can appear in many different guises and do not necessarily show a characteristic bow shape. The ratio of the H2 v = 2-1 S(1) line to the v = 1-0 S(1) line is variable across the flow and the spatial offset between the peaks of the lines may be used to estimate the inclination of the flow. The radial velocity comes to a maximum behind the apparent apex of the bow shock when the flow is seen at an inclination different from face-on. Under certain circumstances the radial velocity of an expanding bow shock can show the same signatures as a rotating flow. In this case a velocity gradient perpendicular to the outflow direction is a projection

  2. Entropy Generation Across Earth's Bow Shock

    NASA Technical Reports Server (NTRS)

    Parks, George K.; McCarthy, Michael; Fu, Suiyan; Lee E. s; Cao, Jinbin; Goldstein, Melvyn L.; Canu, Patrick; Dandouras, Iannis S.; Reme, Henri; Fazakerley, Andrew; Lin, Naiguo; Wilber, Mark

    2011-01-01

    Earth's bow shock is a transition layer that causes an irreversible change in the state of plasma that is stationary in time. Theories predict entropy increases across the bow shock but entropy has never been directly measured. Cluster and Double Star plasma experiments measure 3D plasma distributions upstream and downstream of the bow shock that allow calculation of Boltzmann's entropy function H and his famous H-theorem, dH/dt O. We present the first direct measurements of entropy density changes across Earth's bow shock. We will show that this entropy generation may be part of the processes that produce the non-thermal plasma distributions is consistent with a kinetic entropy flux model derived from the collisionless Boltzmann equation, giving strong support that solar wind's total entropy across the bow shock remains unchanged. As far as we know, our results are not explained by any existing shock models and should be of interests to theorists.

  3. Periodic reversal of direction allows Myxobacteria to swarm

    PubMed Central

    Wu, Yilin; Kaiser, A. Dale; Jiang, Yi; Alber, Mark S.

    2009-01-01

    Many bacteria can rapidly traverse surfaces from which they are extracting nutrient for growth. They generate flat, spreading colonies, called swarms because they resemble swarms of insects. We seek to understand how members of any dense swarm spread efficiently while being able to perceive and interfere minimally with the motion of others. To this end, we investigate swarms of the myxobacterium, Myxococcus xanthus. Individual M. xanthus cells are elongated; they always move in the direction of their long axis; and they are in constant motion, repeatedly touching each other. Remarkably, they regularly reverse their gliding directions. We have constructed a detailed cell- and behavior-based computational model of M. xanthus swarming that allows the organization of cells to be computed. By using the model, we are able to show that reversals of gliding direction are essential for swarming and that reversals increase the outflow of cells across the edge of the swarm. Cells at the swarm edge gain maximum exposure to nutrient and oxygen. We also find that the reversal period predicted to maximize the outflow of cells is the same (within the errors of measurement) as the period observed in experiments with normal M. xanthus cells. This coincidence suggests that the circuit regulating reversals evolved to its current sensitivity under selection for growth achieved by swarming. Finally, we observe that, with time, reversals increase the cell alignment, and generate clusters of parallel cells. PMID:19164578

  4. Maximum bow force revisited.

    PubMed

    Mores, Robert

    2016-08-01

    Schelleng [J. Acoust. Soc. Am. 53, 26-41 (1973)], Askenfelt [J. Acoust. Soc. Am. 86, 503-516 (1989)], Schumacher [J. Acoust. Soc. Am. 96, 1985-1998 (1994)], and Schoonderwaldt, Guettler, and Askenfelt [Acta Acust. Acust. 94, 604-622 (2008)] formulated-in different ways-how the maximum bow force relates to bow velocity, bow-bridge distance, string impedance, and friction coefficients. Issues of uncertainty are how to account for friction or for the rotational admittance of the strings. Related measurements at the respective transitions between regimes of Helmholtz motion and non-Helmholtz motion employ a variety of bowing machines and stringed instruments. The related findings include all necessary parameters except the friction coefficients, leaving the underlying models unconfirmed. Here, a bowing pendulum has been constructed which allows precise measurement of relevant bowing parameters, including the friction coefficients. Two cellos are measured across all strings for three different bow-bridge distances. The empirical data suggest that-taking the diverse elements of existing models as options-Schelleng's model combined with Schumacher's velocity term yields the best fit. Furthermore, the pendulum employs a bow driving mechanism with adaptive impedance which discloses that mentioned regimes are stable and transitions between them sometimes require a hysteresis on related parameters. PMID:27586745

  5. Demographic noise can reverse the direction of deterministic selection.

    PubMed

    Constable, George W A; Rogers, Tim; McKane, Alan J; Tarnita, Corina E

    2016-08-01

    Deterministic evolutionary theory robustly predicts that populations displaying altruistic behaviors will be driven to extinction by mutant cheats that absorb common benefits but do not themselves contribute. Here we show that when demographic stochasticity is accounted for, selection can in fact act in the reverse direction to that predicted deterministically, instead favoring cooperative behaviors that appreciably increase the carrying capacity of the population. Populations that exist in larger numbers experience a selective advantage by being more stochastically robust to invasions than smaller populations, and this advantage can persist even in the presence of reproductive costs. We investigate this general effect in the specific context of public goods production and find conditions for stochastic selection reversal leading to the success of public good producers. This insight, developed here analytically, is missed by the deterministic analysis as well as by standard game theoretic models that enforce a fixed population size. The effect is found to be amplified by space; in this scenario we find that selection reversal occurs within biologically reasonable parameter regimes for microbial populations. Beyond the public good problem, we formulate a general mathematical framework for models that may exhibit stochastic selection reversal. In this context, we describe a stochastic analog to [Formula: see text] theory, by which small populations can evolve to higher densities in the absence of disturbance. PMID:27450085

  6. Astrospheres and Stellar Bow shocks

    NASA Astrophysics Data System (ADS)

    Van Marle, Allard Jan

    2016-07-01

    As stars evolve, they deliver feedback to the surrounding medium in the form of stellar wind and radiation. These shape the surrounding matter, forming what is called an astrosphere, a sphere of influence in which the star dominates the morphology and composition of the surrounding medium. Astrospheres are fascinating objects. Because they are formed through the interaction between the stellar feedback and the interstellar gas, they can tell us a great deal about both. Furthermore, because they are shaped over time they provide us with a window into the past. This is of particular interest for the study of stellar evolution, because the astrosphere reflects changes in the properties of the stellar wind, which relate directly to the properties of the star. A special sub-class of astrospheres, the stellar bow shocks, occur when the progenitor star moves through the surrounding medium at supersonic speed. Because the properties of the bow shock relate directly to both the stellar wind and the interstellar medium, the shape and size of the bow shock can be used to determine these properties. Using state-of-the-art numerical codes, it is possible to simulate the interaction between the stellar wind and radiation and the interstellar medium. These results can then be compared to observations. They can also be used to predict the type of observations that are best suited to study these objects. In this fashion computational and observational astronomy can support each other in their efforts to gain a better understanding of stars and their environment.

  7. Medicine Bow wind project

    NASA Astrophysics Data System (ADS)

    Nelson, L. L.

    1982-05-01

    The Bureau of Reclamation (Bureau) conducted studies for a wind turbine field of 100 MW at a site near Medicine Bow, WY, one of the windiest areas in the United States. The wind turbine system would be electrically interconnected to the existing Federal power grid through the substation at Medicine Bow. Power output from the wind turbines would thus be integrated with the existing hydroelectric system, which serves as the energy storage system. An analysis based on 'willingness to pay' was developed. Based on information from the Department of Energy's Western Area Power Administration (Western), it was assumed that 90 mills per kWh would represent the 'willingness to pay' for onpeak power, and 45 mills per kWh for offpeak power. The report concludes that a 100-MW wind field at Medicine Bow has economic and financial feasibility. The Bureau's construction of the Medicine Bow wind field could demonstrate to the industry the feasibility of wind energy.

  8. Christmas bow tragedies.

    PubMed

    Buntain, W L; Benton, J W; Gutierrez, J F

    1979-11-01

    Two cases of fatal accidents involving plastic buttons from Christmas bows are described. Although accidents are the commonest cause of death in children less than 3 years old, governmental mechanisms, properly enforced, can be instrumental in preventing such catastrophies.

  9. Differential Binding Models for Direct and Reverse Isothermal Titration Calorimetry.

    PubMed

    Herrera, Isaac; Winnik, Mitchell A

    2016-03-10

    Isothermal titration calorimetry (ITC) is a technique to measure the stoichiometry and thermodynamics from binding experiments. Identifying an appropriate mathematical model to evaluate titration curves of receptors with multiple sites is challenging, particularly when the stoichiometry or binding mechanism is not available. In a recent theoretical study, we presented a differential binding model (DBM) to study calorimetry titrations independently of the interaction among the binding sites (Herrera, I.; Winnik, M. A. J. Phys. Chem. B 2013, 117, 8659-8672). Here, we build upon our DBM and show its practical application to evaluate calorimetry titrations of receptors with multiple sites independently of the titration direction. Specifically, we present a set of ordinary differential equations (ODEs) with the general form d[S]/dV that can be integrated numerically to calculate the equilibrium concentrations of free and bound species S at every injection step and, subsequently, to evaluate the volume-normalized heat signal (δQ(V) = δq/dV) of direct and reverse calorimetry titrations. Additionally, we identify factors that influence the shape of the titration curve and can be used to optimize the initial concentrations of titrant and analyte. We demonstrate the flexibility of our updated DBM by applying these differentials and a global regression analysis to direct and reverse calorimetric titrations of gadolinium ions with multidentate ligands of increasing denticity, namely, diglycolic acid (DGA), citric acid (CIT), and nitrilotriacetic acid (NTA), and use statistical tests to validate the stoichiometries for the metal-ligand pairs studied.

  10. 43. Bow thruster room. Bow thruster engine not used for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. Bow thruster room. Bow thruster engine not used for powering hydraulics to boom as in some other tenders in same class. - U.S. Coast Guard Cutter BRAMBLE, Waterfront at Lincoln Avenue, Port Huron, St. Clair County, MI

  11. The Retarding Force on a Fan-Cart Reversing Direction

    NASA Astrophysics Data System (ADS)

    Aurora, Tarlok S.; Brunner, Bernard J.

    2012-03-01

    In introductory physics, students learn that an object tossed upward has a constant downward acceleration while going up, at the highest point and while falling down. To demonstrate this concept, a self-propelled fan cart system is used on a frictionless track. A quick push is given to the fan cart and it is allowed to move away on a track under the opposing action of thrust produced by the fan. The cart moves away from the starting point, stops at some distance away and then reverses its motion. Students frequently predict the acceleration of the cart to be constant during the round trip motion. When an experiment was performed, it was found that the cart acceleration was not constant during the round trip. After ruling out any equipment problem, the cart motion was analyzed using Newton's laws with the inclusion of retarding forces. Results showed that the total retarding force was more significant than previously assumed, and it reversed direction during motion. This analysis seems to offer a reasonable explanation for the discrepancy between prediction and observation. In addition, students learned that the discrepancy was due to a real physical effect, and not an artifact of the equipment. This analysis offers a problem solving opportunity in introductory physics laboratory.

  12. The retarding force on a fan-cart reversing direction

    NASA Astrophysics Data System (ADS)

    Aurora, Tarlok S.; Brunner, Bernard J.

    2011-01-01

    In introductory physics, students learn that an object tossed upward has a constant downward acceleration while going up, at the highest point and while falling down. To demonstrate this concept, a self-propelled fan cart system is used on a frictionless track. A quick push is given to the fan cart and it is allowed to move away on a track under the opposing action of thrust produced by the fan. The cart moves away from the starting point, stops at some distance away and then reverses its motion. Students frequently predict the acceleration of the cart to be constant during the round trip motion. When an experiment was performed, it was found that the cart acceleration was not constant during the round trip. After ruling out any equipment problem, the cart motion was analysed using Newton's laws with the inclusion of retarding forces. Results showed that the total retarding force was more significant than previously assumed, and it reversed direction during motion. This analysis seems to offer a reasonable explanation for the discrepancy between prediction and observation. In addition, students learned that the discrepancy was due to a real physical effect, and not an artefact of the equipment. This analysis offers a problem solving opportunity in the introductory physics laboratory.

  13. Testing bow shock models

    NASA Astrophysics Data System (ADS)

    Alrefay, Thamer; Meziane, Karim; Hamza, A. M.

    2016-07-01

    Space plasmas studies of bow shock dynamics, given the fundamental transport role and impact natural transition boundaries, have continued to attract much interest. With the overwhelming availability of data collected by various space science missions, several empirical models have been put forward to account for the location of the Earth's bow shock. Various solar wind and IMF measured parameters are used to constrain the proposed models published in the literature. For each of these empirical models, the bow shock nose velocity, at the standoff distance, is computed; each of these velocities is then compared with the observed shock speed as determined from a multipoint measurement provided by the Cluster quartet. The present study reveals to what extent the model parameters used are significant and determinant, and suggests that some empirical models are more accurate than others are.

  14. Neptune inbound bow shock

    NASA Technical Reports Server (NTRS)

    Szabo, Adam; Lepping, Ronald P.

    1995-01-01

    Voyager 2 crossed the inbound or upstream Neptunian bow shock at 1430 spacecraft event time on August 24 in 1989 (Belcher et al., 1989). The plasma and magnetic field measurements allow us to study the solar wind interaction with the outermost gas giant. To fully utilize all of the spacecraft observations, an improved nonlinear least squares, 'Rankine-Hugoniot' magnetohydrodynamic shock-fitting technique has been developed (Szabo, 1994). This technique is applied to the Neptunian data set. We find that the upstream bow shock normal points nearly exactly toward the Sun consistent with any reasonable large-scale model of the bow shock for a near subsolar crossing. The shock was moving outward with a speed of 14 +/- 12 km/s. The shock can be characterized as a low beta, high Mach number, strong quasi-perpendicular shock. Finally, the shock microstructure features are resolved and found to scale well with theoretical expectations.

  15. Sequencing by hybridization by cooperating direct and reverse spectra.

    PubMed

    Heath, Samuel A; Preparata, Franco P; Young, Joel

    2003-01-01

    DNA sequencing by hybridization, potentially a powerful alternative to standard wet lab techniques, has received renewed interest after a novel probing scheme has been recently proposed whose performance for the first time asymptotically meets the information theory bound. After settlement of the question of asymptotic performance, there remains the issue of algorithmic fine tunings aimed at improving the performance "constants," with substantial practical implications. In this paper, we show that a probing scheme based on the joint use of direct and reverse spectra (tandem spectra) for a given gapped probing pattern achieves a performance improvement per unit of microarray area of about 5/4 and does not appear to be susceptible to further improvement by increasing the number of cooperating spectra. In other words, tandem-spectrum reconstruction is the best known technique for sequencing by hybridization.

  16. Multi-spacecraft analysis of the ion ramp of interplanetary shocks and bow shock

    NASA Astrophysics Data System (ADS)

    Goncharov, Oleksandr; Koval, Andriy; Zastenker, Georgy; Nemecek, Zdenek; Safrankova, Jana; Prech, Lubomir

    2016-07-01

    Collisionless shocks play a significant role in the solar wind interaction with the Earth. Fast forward shocks driven by coronal mass ejections or by interaction of fast and slow solar wind streams can be encountered in the interplanetary space, whereas the bow shock is a standing fast reverse shock formed by interaction of the supersonic solar wind with the Earth magnetic field. Both types of shocks are responsible for a transformation of a part of the energy of the directed solar wind motion to plasma heating and to acceleration of reflected particles to high energies. These processes are closely related to shock front structure. The paper compares the structure of low-Mach number fast forward interplanetary shocks registered by Wind and ACE with observations of bow shock crossings observed by Cluster, THEMIS, and Spektr-R spacecraft. An application of the high-time resolution data allows us to distinguish formation mechanisms of both types of shocks.

  17. Martian bow shock - PHOBOS observations

    NASA Astrophysics Data System (ADS)

    Schwingenschuh, K.; Riedler, W.; Lichtenegger, H.; Yeroshenko, Ye.; Sauer, K.; Luhmann, J. G.; Ong, M.; Russell, C. T.

    1990-05-01

    Data obtained with the Magma magnetometer on the subsolar passes of the Phobos spacecraft during its 3 elliptic orbits reveals a turbulent bow shock with a strong foot consistent with the reflection of solar wind protons. The bow shock lies at a subsolar distance of 1.47 + or - .03 R(M). The circular orbit phase of the mission reveals a bow shock with a highly varying location. The median terminator crossing lies at 2.72 Mars radii. The location of the bow shock in the terminator plane is sensitive to neither the EUV flux nor to planetary longitude.

  18. Martian bow shock: Phobos observations

    SciTech Connect

    Schwingenschuh, K.; Riedler, W.; Lichtenegger, H. ); Yeroshenko, Ye. ); Sauer, K. ); Luhmann, J.G.; Ong, M.; Russell, C.T. )

    1990-05-01

    Data obtained with the MAGMA magnetometer on the subsolar passes of the Phobos spacecraft during its 3 elliptic orbits reveals a turbulent bow shock with a strong foot consistent with the reflection of solar wind protons. The bow shock lies at a subsolar distance of 1.47 {plus minus} .03 R{sub M}. The circular orbit phase of the mission reveals a bow shock with a highly varying location. The median terminator crossing lies at 2.72 Mars radii. The location of the bow shock in the terminator plane is sensitive to neither the EUV flux nor to planetary longitude.

  19. Suprathermal ions observed upstream of the Venus bow shock

    NASA Technical Reports Server (NTRS)

    Moore, K. R.; Mccomas, D. J.; Russell, C. T.; Mihalov, J. D.

    1989-01-01

    Suprathermal ions with arrival directions quite distinct from those of the solar wind have been detected upstream of the Venus bow shock. The possibility that these events could be caused by instrumental or spacecraft effects or that they could be either solar wind disturbances, planetary pickup ions, or suprethermal ions upstream of the Venus bow shock is examined. It is concluded that they are consistent with upstream suprathermal ions associated with the bow shock that are observed downstream from the points of intersection of their extrapolated trajectories with the shock.

  20. Coordination of bowing and fingering in violin playing.

    PubMed

    Baader, Andreas P; Kazennikov, Oleg; Wiesendanger, Mario

    2005-05-01

    Playing string instruments implies motor skills including asymmetrical interlimb coordination. How special is musical skill as compared to other bimanually coordinated, non-musical skillful performances? We succeeded for the first time to measure quantitatively bimanual coordination in violinists playing repeatedly a simple tone sequence. A motion analysis system was used to record finger and bow trajectories for assessing the temporal structure of finger-press, finger-lift (left hand), and bow stroke reversals (right arm). The main results were: (1) fingering consisted of serial and parallel (anticipatory) mechanisms; (2) synchronization between finger and bow actions varied from -12 ms to 60 ms, but these 'errors' were not perceived. The results suggest that (1) bow-finger synchronization varied by about 50 ms from perfect simultaneity, but without impairing auditory perception; (2) the temporal structure depends on a number of combinatorial mechanisms of bowing and fingering. These basic mechanisms were observed in all players, including all amateurs. The successful biomechanical measures of fingering and bowing open a vast practical field of assessing motor skills. Thus, objective assessment of larger groups of string players with varying musical proficiency, or of professional string players developing movement disorders, may be helpful in music education. PMID:15820650

  1. Coordination of bowing and fingering in violin playing.

    PubMed

    Baader, Andreas P; Kazennikov, Oleg; Wiesendanger, Mario

    2005-05-01

    Playing string instruments implies motor skills including asymmetrical interlimb coordination. How special is musical skill as compared to other bimanually coordinated, non-musical skillful performances? We succeeded for the first time to measure quantitatively bimanual coordination in violinists playing repeatedly a simple tone sequence. A motion analysis system was used to record finger and bow trajectories for assessing the temporal structure of finger-press, finger-lift (left hand), and bow stroke reversals (right arm). The main results were: (1) fingering consisted of serial and parallel (anticipatory) mechanisms; (2) synchronization between finger and bow actions varied from -12 ms to 60 ms, but these 'errors' were not perceived. The results suggest that (1) bow-finger synchronization varied by about 50 ms from perfect simultaneity, but without impairing auditory perception; (2) the temporal structure depends on a number of combinatorial mechanisms of bowing and fingering. These basic mechanisms were observed in all players, including all amateurs. The successful biomechanical measures of fingering and bowing open a vast practical field of assessing motor skills. Thus, objective assessment of larger groups of string players with varying musical proficiency, or of professional string players developing movement disorders, may be helpful in music education.

  2. Direct observation of DNA overwinding by reverse gyrase

    PubMed Central

    Ogawa, Taisaku; Yogo, Katsunori; Furuike, Shou; Sutoh, Kazuo; Kikuchi, Akihiko; Kinosita, Kazuhiko

    2015-01-01

    Reverse gyrase, found in hyperthermophiles, is the only enzyme known to overwind (introduce positive supercoils into) DNA. The ATP-dependent activity, detected at >70 °C, has so far been studied solely by gel electrophoresis; thus, the reaction dynamics remain obscure. Here, we image the overwinding reaction at 71 °C under a microscope, using DNA containing consecutive 30 mismatched base pairs that serve as a well-defined substrate site. A single reverse gyrase molecule processively winds the DNA for >100 turns. Bound enzyme shows moderate temperature dependence, retaining significant activity down to 50 °C. The unloaded reaction rate at 71 °C exceeds five turns per second, which is >102-fold higher than hitherto indicated but lower than the measured ATPase rate of 20 s−1, indicating loose coupling. The overwinding reaction sharply slows down as the torsional stress accumulates in DNA and ceases at stress of mere ∼5 pN⋅nm, where one more turn would cost only sixfold the thermal energy. The enzyme would thus keep DNA in a slightly overwound state to protect, but not overprotect, the genome of hyperthermophiles against thermal melting. Overwinding activity is also highly sensitive to DNA tension, with an effective interaction length exceeding the size of reverse gyrase, implying requirement for slack DNA. All results point to the mechanism where strand passage relying on thermal motions, as in topoisomerase IA, is actively but loosely biased toward overwinding. PMID:26023188

  3. AOTV bow shock location

    NASA Technical Reports Server (NTRS)

    Desautel, D.

    1985-01-01

    Hypersonic bow-shock location and geometry are of central importance to the aerodynamics and aerothermodynamics of aeroassisted orbital transfer vehicles (AOTVs), but they are difficult to predict for a given vehicle configuration. This paper reports experimental measurements of shock standoff distance for the 70 deg cone AOTV configuration in shock-tunnel-test flows at Mach numbers of 3.8 to 7.9 and for angles of attack from 0 deg to 20 deg. The controlling parameter for hypersonic bow-shock standoff distance (for a given forebody shape) is the mean normal-shock density ratio. Values for this parameter in the tests reported are in the same range as those of the drag-brake AOTV perigee regime. Results for standoff distance are compared with those previously reported in the literature for this AOTV configuration. It is concluded that the AOTV shock standoff distance for the conical configuration, based on frustrum (base) radius, is equivalent to that of a sphere with a radius about 35 percent greater than that of the cone; the distance is, therefore, much less than reported in previous studies. Some reasons for the discrepancies between the present and previous are advanced. The smaller standoff distance determined here implies there will be less radiative heat transfer than was previously expected.

  4. The earth's foreshock, bow shock, and magnetosheath

    SciTech Connect

    Onsager, T.G.; Thomsen, M.F. )

    1991-01-01

    Studies directly pertaining to the earth's foreshock, bow shock, and magnetosheath are reviewed, and some comparisons are made with data on other planets. Topics considered in detail include the electron foreshock, the ion foreshock, the quasi-parallel shock, the quasi-perpendicular shock, and the magnetosheath. Information discussed spans a broad range of disciplines, from large-scale macroscopic plasma phenomena to small-scale microphysical interactions. 184 refs.

  5. Analysis of the Giacobini-Zinner bow wave

    SciTech Connect

    Smith, E.J.; Slavin, J.A.; Bame, S.J.; Thomsen, M.F.; Cowley, S.W.H.; Richardson, I.G.; Hovestadt, D.; Ipavich, F.M.; Ogilvie, K.W.; Coplan, M.A.

    1986-01-01

    The cometary bow wave of P/Giacobini-Zinner has been analyzed using the complete set of ICE field and particle observations to determine if it is a shock. Changes in the magnetic field and plasma flow velocities from upstream to downstream have been analyzed to determine the direction of the normal and the propagation velocity of the bow wave. The velocity has then been compared with the fast magnetosonic wave speed upstream to derive the Mach number and establish whether it is ''supersonic'', i.e., a shock, or ''subsonic,'' i.e., a large amplitude wave. The various measurements have also been compared with values derived from a Rankine-Hugoniot analysis. The results indicate that, inbound, the bow wave is a shock with M = 1.5. Outbound, a subsonic mach number is obtained, however, arguments are presented that the bow wave is also likely to be a shock at this location. 11 refs., 4 figs., 2 tabs.

  6. A comparative review of bow shocks and magnetopauses

    NASA Technical Reports Server (NTRS)

    Lepping, R. P.

    1984-01-01

    Bow shock and magnetopauses formation is discussed. Plasma and magnetic field environments of all the planets from Mercury to Saturn were measured. It was found that all the planets have bow shocks and almost all have a magnetopause. Venus is the only planet with no measurable intrinsic magnetic field and the solar wind interacts directly with Venus' ionosphere. The bow shock characteristics depend on the changing solar wind conditions. The shape of a magnetopause or any obstacle to flow depends on the three dimensional pressure profile that it presents to the solar wind. Jupiter is unusual because of the considerable amount of plasma which is contained in its magnetosphere. Magnetopause boundaries in ecliptic plane projection are modelled by segments of ellipses, matched to straight lines for the magnetotool boundaries or parabolas. Specific properties of known planetary bow shocks and magnetopauses are reviewed.

  7. Enhancing complex network controllability by minimum link direction reversal

    NASA Astrophysics Data System (ADS)

    Hou, Lvlin; Lao, Songyang; Small, Michael; Xiao, Yandong

    2015-07-01

    Controllability of complex networks has recently become one of the most popular research fields, but the importance of link direction for controllability has not been systematically considered. We propose a method to enhance controllability of a directed network by changing the direction of a small fraction of links while keeping the total number of links unchanged. The main idea of the method is to find candidate links based on the matching path. Extensive numerical simulation on many modeled networks demonstrates that this method is effective. Furthermore, we find that the nodes linked to candidate links have a distinct character, which provide us with a strategy to improve the controllability based on the local structure. Since the whole topology of many real networks is not visible and we only get some local structure information, this strategy is potentially more practical compared to those that demand complete topology information.

  8. Reversing bone loss by directing mesenchymal stem cells to bone.

    PubMed

    Yao, Wei; Guan, Min; Jia, Junjing; Dai, Weiwei; Lay, Yu-An E; Amugongo, Sarah; Liu, Ruiwu; Olivos, David; Saunders, Mary; Lam, Kit S; Nolta, Jan; Olvera, Diana; Ritchie, Robert O; Lane, Nancy E

    2013-09-01

    Bone regeneration by systemic transplantation of mesenchymal stem cells (MSCs) is problematic due to the inability to control the MSCs' commitment, growth, and differentiation into functional osteoblasts on the bone surface. Our research group has developed a method to direct the MSCs to the bone surface by conjugating a synthetic peptidomimetic ligand (LLP2A) that has high affinity for activated α4β1 integrin on the MSC surface, with a bisphosphonates (alendronate) that has high affinity for bone (LLP2A-Ale), to direct the transplanted MSCs to bone. Our in vitro experiments demonstrated that mobilization of LLP2A-Ale to hydroxyapatite accelerated MSC migration that was associated with an increase in the phosphorylation of Akt kinase and osteoblastogenesis. LLP2A-Ale increased the homing of the transplanted MSCs to bone as well as the osteoblast surface, significantly increased the rate of bone formation and restored both trabecular and cortical bone loss induced by estrogen deficiency or advanced age in mice. These results support LLP2A-Ale as a novel therapeutic option to direct the transplanted MSCs to bone for the treatment of established bone loss related to hormone deficiency and aging.

  9. Propagation direction reversal of ionization zones in the transition between high and low current magnetron sputtering

    SciTech Connect

    School of Materials Science and Engineering, State Key Lab for Materials Processing and Die & Mold Technology, Huazhong University of Science and Technology, Wuhan 430074, China; Department of Physics, University of California Berkeley, Berkeley, California 94720, USA; Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, California 94720, USA; Yang, Yuchen; Liu, Jason; Liu, Lin; Anders, André

    2014-12-11

    Past research has revealed the propagation of dense, asymmetric ionization zones in both high and low current magnetron discharges. Here we report about the direction reversal of ionization zone propagation as observed with fast cameras. At high currents, zones move in the E B direction with velocities of 103 to 104 m/s. However at lower currents, ionization zones are observed to move in the opposite, the -E B direction, with velocities ~;; 103 m/s. It is proposed that the direction reversal is associated with the local balance of ionization and supply of neutrals in the ionization zone.

  10. Recognising faces: effects of lighting direction, inversion, and brightness reversal.

    PubMed

    Johnston, A; Hill, H; Carman, N

    1992-01-01

    When information about three-dimensional shape obtained from shading and shadows is ambiguous, the visual system favours an interpretation of surface geometry which is consistent with illumination from above. If pictures of top-lit faces are rotated the resulting stimulus is both figurally inverted and illuminated from below. In this study the question of whether the effects of figural inversion and lighting orientation on face recognition are independent or interactive is addressed. Although there was a clear inversion effect for faces illuminated from the front and above, the inversion effect was found to be reduced or eliminated for faces illuminated from below. A strong inversion effect for photographic negatives was also found but in this case the effect was not dependent on the direction of illumination. These findings are interpreted as evidence to suggest that lighting faces from below disrupts the formation of surface-based representations of facial shape. PMID:1437456

  11. Recognising faces: effects of lighting direction, inversion, and brightness reversal.

    PubMed

    Johnston, Alan; Hill, Harold; Carman, Nicole

    2013-01-01

    When information about three-dimensional shape obtained from shading and shadows is ambiguous, the visual system favours an interpretation of surface geometry which is consistent with illumination from above. If pictures of top-lit faces are rotated the resulting stimulus is both figurally inverted and illuminated from below. In this study the question of whether the effects of figural inversion and lighting orientation on face recognition are independent or interactive is addressed. Although there was a clear inversion effect for faces illuminated from the front and above, the inversion effect was found to be reduced or eliminated for faces illuminated from below. A strong inversion effect for photographic negatives was also found but in this case the effect was not dependent on the direction of illumination. These findings are interpreted as evidence to suggest that lighting faces from below disrupts the formation of surface-based representations of facial shape. PMID:24601034

  12. Direct Hydrogenation Magnesium Boride to Magnesium Borohydride: Demonstration of >11 Weight Percent Reversible Hydrogen Storage

    SciTech Connect

    Severa, Godwin; Ronnebro, Ewa; Jensen, Craig M.

    2010-11-16

    We here for the first time demonstrate direct hydrogenation of magnesium boride, MgB2, to magnesium borohydride, Mg(BH4)2 at 900 bar H2-pressures and 400°C. Upon 14.8wt% hydrogen release, the end-decomposition product of Mg(BH4)2 is MgB2, thus, this is a unique reversible path here obtaining >11wt% H2 which implies promise for a fully reversible hydrogen storage material.

  13. Reversals in Direct Numerical Simulations of the Geodynamo: a Statistical Analysis

    NASA Astrophysics Data System (ADS)

    Meduri, D.; Wicht, J.; Schmitt, D.

    2013-12-01

    original Exponential fit of stable polarity intervals to a Gamma distribution. Statistical analyses of geomagnetic polarity epochs might be biased in the same way by reversal durations. The current development of mean-field dynamo models, based on helicity profiles directly retrieved from 3D geodynamo simulations, can play the key role of discriminating among different physical processes that produce the observed distribution profile of polarity intervals.

  14. Rare Etiology of Bow Hunter’s Syndrome and Systematic Review of Literature

    PubMed Central

    Rastogi, Vaibhav; Rawls, Ashley; Moore, Omar; Victorica, Benjamin; Khan, Sheema; Saravanapavan, Pradeepan; Midivelli, Sunitha; Raviraj, Prathap; Khanna, Anna; Bidari, Sharathchandra; Hedna, Vishnumurthy S

    2015-01-01

    BACKGROUND Bow Hunter’s Syndrome is a mechanical occlusion of the vertebral artery which leads to a reduction in blood flow in posterior cerebral circulation resulting in transient reversible symptomatic vertebrobasilar insufficiency. CASE DESCRIPTION We present a case of Bow Hunter’s syndrome in a 53-year-old male that occurred after the patient underwent surgical correction of a proximal left subclavian artery aneurysm. Shortly after the surgery, the patient began to complain of transient visual changes, presyncopal spells, and dizziness upon turning his head to the left. A transcranial doppler ultrasound confirmed the diagnosis of Bow Hunter’s syndrome. SYSTEMIC REVIEW We analyzed the data on 153 patients with Bow Hunter’s syndrome from the literature. An osteophyte was the most common cause of vertebral artery occlusion, and left vertebral artery was more commonly involved in patients with Bow Hunter’s syndrome. Dynamic angiography was the definitive imaging modality to confirm the diagnosis, and surgery was most successful in alleviating symptoms. CONCLUSION We believe that this is the first case of iatrogenic Bow Hunter’s syndrome after surgical intervention for an aneurysm repair, and the largest review of literature of Bow Hunter’s syndrome. Dynamic angiography is the gold standard for the diagnosis of Bow Hunter’s syndrome. Surgery should be considered as the primary treatment approach in these patients, especially those who have bony compression as the etiology. PMID:26301025

  15. Reversals.

    ERIC Educational Resources Information Center

    National Center on Educational Media and Materials for the Handicapped, Columbus, OH.

    Selected from the National Instructional Materials Information System (NIMIS)--a computer based on-line interactive retrieval system on special education materials--the bibliography covers nine materials for remediating reversals in handicapped students at the early childhood and elementary levels. Entries are presented in order of NIMIS accession…

  16. The heliosphere's interstellar interaction: no bow shock.

    PubMed

    McComas, D J; Alexashov, D; Bzowski, M; Fahr, H; Heerikhuisen, J; Izmodenov, V; Lee, M A; Möbius, E; Pogorelov, N; Schwadron, N A; Zank, G P

    2012-06-01

    As the Sun moves through the local interstellar medium, its supersonic, ionized solar wind carves out a cavity called the heliosphere. Recent observations from the Interstellar Boundary Explorer (IBEX) spacecraft show that the relative motion of the Sun with respect to the interstellar medium is slower and in a somewhat different direction than previously thought. Here, we provide combined consensus values for this velocity vector and show that they have important implications for the global interstellar interaction. In particular, the velocity is almost certainly slower than the fast magnetosonic speed, with no bow shock forming ahead of the heliosphere, as was widely expected in the past. PMID:22582011

  17. Mechanisms of Amplified Arteriogenesis in Collateral Artery Segments Exposed to Flow Direction Reversal

    PubMed Central

    Heuslein, Joshua L.; Meisner, Joshua K.; Li, Xuanyue; Song, Ji; Vincentelli, Helena; Leiphart, Ryan J.; Ames, Elizabeth G.; Price, Richard J.

    2015-01-01

    Objective Collateral arteriogenesis, the growth of existing arterial vessels to a larger diameter, is a fundamental adaptive response that is often critical for the perfusion and survival of tissues downstream of chronic arterial occlusion(s). Shear stress regulates arteriogenesis; however, the arteriogenic significance of flow direction reversal, occurring in numerous collateral artery segments after femoral artery ligation (FAL), is unknown. Our objective was to determine if flow direction reversal in collateral artery segments differentially regulates endothelial cell signaling and arteriogenesis. Approach and Results Collateral segments experiencing flow reversal after FAL in C57BL/6 mice exhibit increased pericollateral macrophage recruitment, amplified arteriogenesis (30% diameter and 2.8-fold conductance increases), and remarkably permanent (12 weeks post-FAL) remodeling. Genome-wide transcriptional analyses on HUVECs exposed to flow reversal conditions mimicking those occurring in-vivo yielded 10-fold more significantly regulated transcripts, as well as enhanced activation of upstream regulators (NFκB, VEGF, FGF2, TGFβ) and arteriogenic canonical pathways (PKA, PDE, MAPK). Augmented expression of key pro-arteriogenic molecules (KLF2, ICAM-1, eNOS) was also verified by qRT-PCR, leading us to test whether ICAM-1 and/or eNOS regulate amplified arteriogenesis in flow-reversed collateral segments in-vivo. Interestingly, enhanced pericollateral macrophage recruitment and amplified arteriogenesis was attenuated in flow-reversed collateral segments after FAL in ICAM-1−/− mice; however, eNOS−/− mice showed no such differences. Conclusions Flow reversal leads to a broad amplification of pro-arteriogenic endothelial signaling and a sustained ICAM-1-dependent augmentation of arteriogenesis. Further investigation of the endothelial mechanotransduction pathways activated by flow reversal may lead to more effective and durable therapeutic options for arterial

  18. Some aspects of vocal fold bowing.

    PubMed

    Tanaka, S; Hirano, M; Chijiwa, K

    1994-05-01

    Bowing of the vocal fold frequently occurs in patients with vocal fold paralysis (VFP), those with sulcus vocalis, and those who have had laser surgery. Additionally, there are vocal folds that present bowing with no noticeable organic lesion. For the purpose of investigating the causes and mechanisms of vocal fold bowing, consecutive fiberscopic videorecordings of 127 patients with VFP, 33 with sulcus vocalis, 33 with laser surgery, and 33 with dysphonia having no clinically noticeable organic lesion were reviewed. Sixty-nine percent of the paralyzed vocal folds had bowing, and the occurrence of bowing was significantly related to the activity of the thyroarytenoid muscle as measured by electromyography. The cricothyroid activity had no significant relationship to vocal fold bowing. All vocal folds with sulcus presented with bowing. Thirty-five percent of the vocal folds that had had laser surgery had bowing. The extent of tissue removal was closely related to the occurrence of bowing. Twelve cases with no organic lesion had vocal fold bowing. Of these 12 patients, 8 were male and 9 were older than 60 years. Some aging process in the mucosa was presumed to be the cause of the bowing in this age group of patients without clinically noticeable organic lesions. Causes of vocal fold bowing in the younger group of patients without organic lesions were not determined in this study.

  19. Some aspects of vocal fold bowing.

    PubMed

    Tanaka, S; Hirano, M; Chijiwa, K

    1994-05-01

    Bowing of the vocal fold frequently occurs in patients with vocal fold paralysis (VFP), those with sulcus vocalis, and those who have had laser surgery. Additionally, there are vocal folds that present bowing with no noticeable organic lesion. For the purpose of investigating the causes and mechanisms of vocal fold bowing, consecutive fiberscopic videorecordings of 127 patients with VFP, 33 with sulcus vocalis, 33 with laser surgery, and 33 with dysphonia having no clinically noticeable organic lesion were reviewed. Sixty-nine percent of the paralyzed vocal folds had bowing, and the occurrence of bowing was significantly related to the activity of the thyroarytenoid muscle as measured by electromyography. The cricothyroid activity had no significant relationship to vocal fold bowing. All vocal folds with sulcus presented with bowing. Thirty-five percent of the vocal folds that had had laser surgery had bowing. The extent of tissue removal was closely related to the occurrence of bowing. Twelve cases with no organic lesion had vocal fold bowing. Of these 12 patients, 8 were male and 9 were older than 60 years. Some aging process in the mucosa was presumed to be the cause of the bowing in this age group of patients without clinically noticeable organic lesions. Causes of vocal fold bowing in the younger group of patients without organic lesions were not determined in this study. PMID:8179251

  20. Nonlinear Interaction of the Solar Wind with Earth's Bow Shock

    NASA Astrophysics Data System (ADS)

    Parks, George; Yang, Zhongwei; Liu, Ying; Lee, Ensang; Lin, Naiguo; Fu, Suiyan; Cao, Jinbin; Canu, Patrick; Dandouras, Iannis; Reme, Henri; Goldstein, Melvyn

    2014-05-01

    The bow shock is the best-known collisionless shocks in nature. We have known from early on that the solar wind (SW) interaction with the bow shock produces gyrating and reflected particles. Some of these particles travel back into the upstream region, perturb the oncoming SW, and excite a host of nonlinear structures including hot flow anomalies, foreshock cavities and density holes. We have examined these nonlinear structures using data from 2003 when the four Cluster satellites were in a string-of-pearl configuration. We find that the nonlinear structures are evolving as they are convected with the solar wind toward Earth producing many shock-like features similar to those at the bow shock. Full 1D PIC simulation has reproduced many of the features, but the simulation requirements are different from observations. For example, the simulation shows that directly transmitted SW occurs only when the Mach number is small (sub-critical shocks). However, observations show that SW particles can penetrate the bow shock even in super-critical perpendicular shocks. This talk will discuss the new observations and simulation results with emphasis on understanding the SW dissipation mechanisms across the bow shock.

  1. Reversing the direction in a light-driven rotary molecular motor

    NASA Astrophysics Data System (ADS)

    Ruangsupapichat, Nopporn; Pollard, Michael M.; Harutyunyan, Syuzanna R.; Feringa, Ben L.

    2011-01-01

    Biological rotary motors can alter their mechanical function by changing the direction of rotary motion. Achieving a similar reversal of direction of rotation in artificial molecular motors presents a fundamental stereochemical challenge: how to change from clockwise to anticlockwise motion without compromising the autonomous unidirectional rotary behaviour of the system. A new molecular motor with multilevel control of rotary motion is reported here, in which the direction of light-powered rotation can be reversed by base-catalysed epimerization. The key steps are deprotonation and reprotonation of the photochemically generated less-stable isomers during the 360° unidirectional rotary cycle, with complete inversion of the configuration at the stereogenic centre. The ability to change directionality is an essential step towards mechanical molecular systems with adaptive functional behaviour.

  2. Comparison between direct and reverse electroporation of cells in situ: a simulation study.

    PubMed

    Towhidi, Leila; Khodadadi, Delaram; Maimari, Nataly; Pedrigi, Ryan M; Ip, Henry; Kis, Zoltan; Kwak, Brenda R; Petrova, Tatiana W; Delorenzi, Mauro; Krams, Rob

    2016-03-01

    The discovery of the human genome has unveiled new fields of genomics, transcriptomics, and proteomics, which has produced paradigm shifts on how to study disease mechanisms, wherein a current central focus is the understanding of how gene signatures and gene networks interact within cells. These gene function studies require manipulating genes either through activation or inhibition, which can be achieved by temporarily permeabilizing the cell membrane through transfection to delivercDNAorRNAi. An efficient transfection technique is electroporation, which applies an optimized electric pulse to permeabilize the cells of interest. When the molecules are applied on top of seeded cells, it is called "direct" transfection and when the nucleic acids are printed on the substrate and the cells are seeded on top of them, it is termed "reverse" transfection. Direct transfection has been successfully applied in previous studies, whereas reverse transfection has recently gained more attention in the context of high-throughput experiments. Despite the emerging importance, studies comparing the efficiency of the two methods are lacking. In this study, a model for electroporation of cells in situ is developed to address this deficiency. The results indicate that reverse transfection is less efficient than direct transfection. However, the model also predicts that by increasing the concentration of deliverable molecules by a factor of 2 or increasing the applied voltage by 20%, reverse transfection can be approximately as efficient as direct transfection.

  3. Foreshock ions observed behind the Martian bow shock

    NASA Astrophysics Data System (ADS)

    Frahm, R. A.; Yamauchi, M.; Winningham, J. D.; Lundin, R.; Sharber, J. R.; Nilsson, H.; Coates, A. J.

    2016-08-01

    The Mars Express Analyzer of Space Plasmas and Energetic Atoms experiment contains ion and electron instruments for conducting plasma measurements. On January 23, 2012, during in-bound travel of Mars Express in the southern hemisphere of Mars from its dawn side toward periapsis at dusk, the plasma instruments measured foreshock-like ion beams extending from outside the bow shock and into the magnetosphere, continuing to a distance of about a proton gyroradius from the bow shock. These ion beams were mostly protons, were observed to have energies greater than solar wind protons, and were not gyrating, in agreement with reflections of the solar wind proton beam. Furthermore, in the foreshock region the ion energy gradually decreased toward the magnetosheath, in agreement with an acceleration by outward-directed electric field in the bowshock. The observations also suggest that this electric field exists even inside the magnetosheath within the distance of a proton gyroradius from the bow shock.

  4. The player and the bowed string: coordination of bowing parameters in violin and viola performance.

    PubMed

    Schoonderwaldt, E

    2009-11-01

    An experiment was conducted with four violin and viola players, measuring their bowing performance using an optical motion capture system and sensors on the bow. The measurements allowed for a detailed analysis of the use and coordination of the main bowing parameters bow velocity, bow force, and bow-bridge distance. An analysis of bowing strategies in detache playing of notes of three durations (0.2, 2, and 4 s) at three dynamic levels (pp, mf, and f) on all four strings is presented, focusing on the "steady" part of the notes. The results revealed clear trends in the coordinated variations of the bowing parameters depending on the constraints of the task, reflecting a common behavior as well as individual strategies. Furthermore, there were clear indications that the players adapted the bowing parameters to the physical properties of the string and the instrument, respecting the limits of the playable control parameter space. PMID:19894847

  5. The player and the bowed string: coordination of bowing parameters in violin and viola performance.

    PubMed

    Schoonderwaldt, E

    2009-11-01

    An experiment was conducted with four violin and viola players, measuring their bowing performance using an optical motion capture system and sensors on the bow. The measurements allowed for a detailed analysis of the use and coordination of the main bowing parameters bow velocity, bow force, and bow-bridge distance. An analysis of bowing strategies in detache playing of notes of three durations (0.2, 2, and 4 s) at three dynamic levels (pp, mf, and f) on all four strings is presented, focusing on the "steady" part of the notes. The results revealed clear trends in the coordinated variations of the bowing parameters depending on the constraints of the task, reflecting a common behavior as well as individual strategies. Furthermore, there were clear indications that the players adapted the bowing parameters to the physical properties of the string and the instrument, respecting the limits of the playable control parameter space.

  6. Universality of 2-State 3-Symbol Reversible Logic Elements — A Direct Simulation Method of a Rotary Element

    NASA Astrophysics Data System (ADS)

    Ogiro, Tsuyoshi; Alhazov, Artiom; Tanizawa, Tsuyoshi; Morita, Kenichi

    A reversible logic element is a primitive from which reversible computing systems can be constructed. A rotary element is a typical 2-state 4-symbol reversible element with logical universality, and we can construct reversible Turing machines from it very simply. There are also many other reversible element with 1-bit memory. So far, it is known that all the 14 kinds of non-degenerate 2-state 3-symbol reversible elements can simulate a Fredkin gate, and hence they are universal. In this paper, we show that all these 14 elements can "directly" simulate a rotary element in a simple and systematic way.

  7. Effects of bowing on perception of attractiveness.

    PubMed

    Osugi, Takayuki; Kawahara, Jun I

    2015-07-01

    Bowing is a greeting behavior. The present study examined the modulation effect of bowing on perception of attractiveness. In each trial, a portrait digitized from university yearbooks was presented on a computer screen. The portrait was mildly tilted toward participants to simulate a greeting bow (25-degree angle). Participants evaluated the subjective attractiveness of the face using a visual analog scale (0-100). The mean attractiveness judgment of the bowing portrait was significantly higher relative to that of the bending-backward or standing-still control conditions (Experiment 1). Additional control experiments revealed that alternative accounts relying on apparent spatial proximity and physical characteristics could not solely explain the effect of bowing (Experiment 2) and indicated that the effect was specific to objects perceived as faces (Experiment 3). Furthermore, observers' in-return bowing behavior did not reduce the bowing effect (Experiment 4), and bowing motion increased the ratings of subjective politeness and submissiveness (Experiment 5). Finally, tilting the 3D faces elicited the same effect from observers as did tilting the still photos (Experiment 6). These results suggest that a tilting motion of portraits (or images of face-like objects) mimicking bowing enhances perceived attractiveness, at least as measured in a culture familiar with greeting by bowing. PMID:25813741

  8. Direct Observation of Reversible Magnesium Ion Intercalation into a Spinel Oxide Host

    SciTech Connect

    Kim, Chunjoong; Phillips, Patrick J.; Key, Baris; Yi, Tanghong; Nordlund, Dennis; Yu, Young-Sang; Bayliss, Ryan D.; Han, Sang-Don; He, Meinan; Zhang, Zhengcheng; Burrell, Anthony K.; Klie, Robert F.; Cabana, Jordi

    2015-04-17

    Direct evidence of Mg2+ intercalation into a spinel-type Mn2O4 is provided. By com­bining tools with different sensitivities, from atomic-resolution X-ray spectro­scopy to bulk X-ray diffraction, it is demonstrated that Mg2+ reversibly occupies the tetrahedral sites of the spinel structure through the reduction of Mn when the electrochemical reaction is performed.

  9. Microtubule polarity and the direction of pigment transport reverse simultaneously in surgically severed melanophore arms.

    PubMed

    McNiven, M A; Wang, M; Porter, K R

    1984-07-01

    The transport of pigment through the long cytoplasmic extensions (arms) of teleost melanophores is a microtubule-dependent event. We have severed the arms from melanophores to test whether microtubules isolated from the centrosome maintain their original polarity and disposition. In addition, we have tested whether arms containing microtubules of mixed polarities alter the direction of pigment transport. We find that microtubules within severed arms eventually change their polarity and reorganize from the arm center as if to form a new minicell. Concomitant with this change is a reversal in the direction of pigment transport.

  10. [The effects on upper first molars by the face-bow construction. Consideration of utilizing the strain gauge method and the computer method of structural analysis].

    PubMed

    Nakamura, R

    1989-04-01

    The present study was undertaken for the purpose of detecting the influence on upper first molars by the dynamic behavior originated in face-bow construction. Tests were made at occipital pull and cervical pull face-bows utilizing strain gauge method and the computer method of structural analysis. As for the occipital pull face-bow, a short outer-bow 35 mm frontward of a tube was bent 30 degrees upward and be pulled in that direction. As for the cervical pull face-bow, a medium outer-bow flash to tube, parallel to the inner-bow was pulled from 20 degrees downward. These two types of face-bows were divided into 4 types, those with loops at the back end (WL) and to those without loops (NL). In the strain gauge method, the force and moment to tubes was measured and compared with the values obtained from theoretical analysis. And in the structural analysis, the data of deflection was compared with each other. Those results indicated that 1. face-bow shows a different force to the molars and a different phase of deflection, according to the difference of it's force concentrative section. 2. the larger the deflection, the larger the deviation of forces on molars from theoretical values. 3. the way of setting loops against the direction of pull alters the phase of deflection of face-bow and the force on molars. 4. existance of loops at inner-bow affects as follows: (1) Reduction of moment of each type of face-bow. (2) Reduction of vertical force at occipital pull face-bow and it's increase at cervical pull face-bow. (3) Resistance for deflection of face-bows in the case of tractive force for closing loops.

  11. Direct-reversible binding of small molecules to G protein βγ subunits

    PubMed Central

    Seneviratne, AMPB; Burroughs, Michael; Giralt, Ernest; Smrcka, Alan V.

    2011-01-01

    Heterotrimeric guanine nucleotide-binding proteins (G proteins) composed of three subunits α, β, γ mediate activation of multiple intracellular signaling cascades initiated by G protein-coupled receptors (GPCRs). Previously our laboratory identified small molecules that bind to Gβγ and interfere with or enhance binding of select effectors with Gβγ. To understand the molecular mechanisms of selectivity and assess binding of compounds to Gβγ, we used biophysical and biochemical approaches to directly monitor small molecule binding to Gβγ. Surface plasmon resonance (SPR) analysis indicated that multiple compounds bound directly to Gβγ with affinities in the high nanomolar to low micromolar range but with surprisingly slow on and off rate kinetics. While the koff was slow for most of the compounds in physiological buffers, they could be removed from Gβγ with mild chaotropic salts or mildly dissociating collision energy in a mass-spectrometer indicating that compound-Gβγ interactions were non-covalent. Finally, at concentrations used to observe maximal biological effects the stoichiometry of binding was 1:1. The results from this study show that small molecule modulation of Gβγ-effector interactions is by specific direct non-covalent and reversible binding of small molecules to Gβγ. This is highly relevant to development of Gβγ targeting as a therapeutic approach since reversible, direct binding is a prerequisite for drug development and important for specificity. PMID:21621014

  12. Search for systemic mass loss in Algols with bow shocks

    NASA Astrophysics Data System (ADS)

    Mayer, A.; Deschamps, R.; Jorissen, A.

    2016-03-01

    Aims: Various studies indicate that interacting binary stars of Algol type evolve non-conservatively. However, direct detections of systemic mass loss in Algols have been scarce so far. We study the systemic mass loss in Algols by looking for the presence of infrared excesses originating from the thermal emission of dust grains, which is linked to the presence of a stellar wind. Methods: In contrast to previous studies, we make use of the fact that stellar and interstellar material is piled up at the edge of the astrosphere where the stellar wind interacts with the interstellar medium. We analyse WISE W3 12 μm and WISE W4 22 μm data of Algol-type binary Be and B[e] stars and the properties of their bow shocks. From the stand-off distance of the bow shock we are able to determine the mass-loss rate of the binary system. Results: Although the velocities of the stars with respect to the interstellar medium are quite low, we find bow shocks present in two systems, namely π Aqr, and ϕ Per; a third system, CX Dra, shows a more irregular circumstellar environment morphology which might somehow be related to systemic mass loss. The properties of the two bow shocks point to mass-loss rates and wind velocities typical of single B stars, which do not support an enhanced systemic mass loss.

  13. Reversal of the bicycle drawing direction in Parkinson's disease by AC pulsed electromagnetic fields.

    PubMed

    Sandyk, R

    1998-09-01

    The Draw-a-Bicycle Test is employed in neuropsychological testing of cognitive skills since the bicycle design is widely known and also because of its complex structure. The Draw-a-Bicycle Test has been administered routinely to patients with Parkinson's disease (PD) and other neurodegenerative disorders to evaluate the effect of transcranial applications of AC pulsed electromagnetic fields (EMFs) in the picotesla flux density on visuoconstructional skills. A seminal observation is reported in 5 medicated PD patients who demonstrated reversal of spontaneous drawing direction of the bicycle after they received a series of transcranial treatments with AC pulsed EMFs. In 3 patients reversal of the bicycle drawing direction was observed shortly after the administration of pulsed EMFs while in 2 patients these changes were observed within a time lag ranging from several weeks to months. All patients also demonstrated a dramatic clinical response to the administration of EMFs. These findings are intriguing because changes in drawing direction do not occur spontaneously in normal individuals as a result of relateralization of cognitive functions. This report suggests that administration of AC pulsed EMFs may induce in some PD patients changes in hemispheric dominance during processing of a visuoconstructional task and that these changes may be predictive of a particularly favourable response to AC pulsed EMFs therapy.

  14. On the peculiar shapes of some pulsar bow-shock nebulae

    NASA Astrophysics Data System (ADS)

    Bandiera, Rino

    Pulsar bow-shock nebulae are pulsar-wind nebulae formed by the direct interaction of pulsar relativistic winds with the interstellar medium. The bow-shock morphology, well outlined in Hα for some objects, is an effect of the supersonic pulsar motion with respect to the ambient medium. However, in a considerable fraction of cases (e.g. the nebulae associated to PSR B2224+65, PSR B0740-28, PSR J2124-3358) clear deviations from the classical bow shock shape are observed. Such deviations are usually interpreted as due to ambient density gradients and/or to pulsar-wind anisotropies. Here I present a different interpretation, aiming at explaining deviations from the standard morphology as signs of the peculiar physical conditions present in these objects. Using dimensional arguments, I show that, unlike normal pulsar-wind nebulae, in pulsar bow-shock nebulae the mean free path of the highest-energy particles may be comparable with the bow-shock head. I then investigate whether this may affect the shape of the bow-shock; for instance, whether a conical bow shock (like that observed in the "Guitar", the nebula associated to PSR B2224+65) does really imply an ambient density gradient. Finally, I discuss some other possible signatures of these high-energy, long mean-free-path particles.

  15. The violin bow: taper, camber and flexibility.

    PubMed

    Gough, Colin

    2011-12-01

    An analytic, small-deflection, simplified model of the modern violin bow is introduced to describe the bending profiles and related strengths of an initially straight, uniform cross-section, stick as a function of bow hair tension. A number of illustrative bending profiles (cambers) of the bow are considered, which demonstrate the strong dependence of the flexibility of the bow on longitudinal forces across the ends of the bent stick. Such forces are shown to be comparable in strength to critical buckling loads causing excessive sideways buckling unless the stick is very straight. Non-linear, large deformation, finite element computations extend the analysis to bow hair tensions comparable with and above the critical buckling strength of the straight stick. The geometric model assumes an expression for the taper of Tourte bows introduced by Vuillaume, which is re-examined and generalized to describe violin, viola and cello bows. A comparison is made with recently published measurements of the taper and bending profiles of a particularly fine bow by Kittel. PMID:22225065

  16. Measurements and efficient simulations of bowed bars

    PubMed

    Essl; Cook

    2000-07-01

    Bowing bar percussion instruments is an increasing part of the repertoire of modern composition and performance. Yet the system has not been studied systematically. In this paper experimental measurements of bars of bar percussion instruments bowed by a double bass bow and by a bowing machine are presented. They examine the relationships between performance parameters and perceptional parameters which are relevant for musical performance. In addition, a new efficient simulation method using a time-domain approach has been developed and the measured results are compared to the simulation. Most measurement results are in good qualitative agreement with the known results of the bowed string. The spectrum of the bowed bar is observed to be harmonic, independent of the harmonicity or inharmonicity of the eigenfrequencies of the bar. Important distinctions from the known results of the bowed string are the weakness or independence of bowing force and velocity on the fundamental frequency and the spectral content of the produced sound. Simulations show qualitative agreement with the measurements.

  17. The violin bow: taper, camber and flexibility.

    PubMed

    Gough, Colin

    2011-12-01

    An analytic, small-deflection, simplified model of the modern violin bow is introduced to describe the bending profiles and related strengths of an initially straight, uniform cross-section, stick as a function of bow hair tension. A number of illustrative bending profiles (cambers) of the bow are considered, which demonstrate the strong dependence of the flexibility of the bow on longitudinal forces across the ends of the bent stick. Such forces are shown to be comparable in strength to critical buckling loads causing excessive sideways buckling unless the stick is very straight. Non-linear, large deformation, finite element computations extend the analysis to bow hair tensions comparable with and above the critical buckling strength of the straight stick. The geometric model assumes an expression for the taper of Tourte bows introduced by Vuillaume, which is re-examined and generalized to describe violin, viola and cello bows. A comparison is made with recently published measurements of the taper and bending profiles of a particularly fine bow by Kittel.

  18. Direct real-space observation of nearly stochastic behavior in magnetization reversal process on a nanoscale

    SciTech Connect

    Im, M.-Y.; Kim, D.-H.; Lee, K.-D.; Fischer, P.; Shin, S.-C.

    2007-06-01

    We report a non-deterministic nature in the magnetization reversal of nanograins of CoCrPt alloy film. Magnetization reversal process of CoCrPt alloy film is investigated using high resolution soft X-ray microscopy which provides real space images with a spatial resolution of 15 nm. Domain nucleation sites mostly appear stochastically distributed within repeated hysteretic cycles, where the correlation increases as the strength of the applied magnetic field increases in the descending and ascending branches of the major hysteresis loop. In addition, domain configuration is mostly asymmetric with inversion of an applied magnetic field in the hysteretic cycle. Nanomagnetic simulation considering thermal fluctuations of the magnetic moments of the grains explains the nearly stochastic nature of the domain nucleation behavior observed in CoCrPt alloy film. With the bit size in high-density magnetic recording media approaching nanometer length scale, one of the fundamental and crucial issues is whether the domain nucleation during magnetization reversal process exhibits a deterministic behavior. Repeatability of local domain nucleation and deterministic switching behavior are basic and essential factors for achieving high performance in high-density magnetic recording [1-3]. Most experimental studies on this issue reported so far have been mainly performed by indirect probes through macroscopic hysteresis loop and Barkhausen pattern measurements, which provide the ensemble-average magnetization. Thus, they are inadequate to gain insight into the domain-nucleation behavior on a nanometer length scale during the magnetization reversal process [4-6]. Very recently, coherent X-ray speckle metrology, where the speckle pattern observed in reciprocal space acts as a fingerprint of the domain configurations, was adopted to investigate stochastic behavior in the magnetization reversal of a Co/Pt multilayer film [7,8]. However, no direct observation on the stochastic behavior of

  19. Multispacecraft observations of energetic ions upstream and downstream of the bow shock

    NASA Technical Reports Server (NTRS)

    Scholer, M.; Moebius, E.; Kistler, L. M.; Klecker, B.; Ipavich, F. M.

    1989-01-01

    Simultaneous measurements of energetic protons and alpha particles were obtained inside and outside of the magnetopause and upstream and downstream of the bow shock. In the magnetosheath, no gradient or streaming is found in the upstream direction. The present results are consistent with first-order Fermi acceleration at the bow shock and subsequent downstream convection, and exclude the possibility of a magnetospheric source for these particles.

  20. Direction reversal of fluctuation-induced biased Brownian motion on distorted ratchets.

    PubMed

    Yan, B; Miura, R M; Chen, Y D

    2001-05-21

    The biased movement of Brownian particles on a fluctuating two-state periodic potential made of identical distorted ratchets is studied. The purpose is to investigate how the direction of the particle movement is related to the asymmetry of the potential. In general, distorting one of the two linear arms of a regular symmetric ratchet (with equal arm lengths) can create a driving force for the Brownian particle to execute biased movement. The direction of the induced biased movement depends on the type of the distortion. It has been found that if one linear arm is kinked into two linear sub-arms, the direction of the movement can be either positive or negative depending on the frequency of the fluctuation and the location and the degree of the kink. In contrast, if one arm of the symmetric ratchet is replaced by a continuous nonlinear sinusoidal function, the movement is always unidirectional. Thus, for the latter case to generate the direction reversal phenomenon, the ratchets have to have an additional asymmetry. We also have found that two potentials with different distorted ratchets can generate identical fluxes if the distortions are polar symmetric about the mid-point of the arm(s) of the basic linear two-arm ratchet. The results are useful for designing experimental apparatuses for the separation of protein particles based on their sizes and charges and the viscosity of the medium.

  1. Oxygen foreshock of Mars and its implication on ion acceleration in the bow shock

    NASA Astrophysics Data System (ADS)

    Yamauchi, Masatoshi; Lundin, Rickard; Frahm, Rudy; Sauvaud, Jean-Andre; Holmstrom, Mats; Barabash, Stas

    2016-04-01

    Ion acceleration inside the bow shock is one of the poorly understood phenomena that has been observed for more than 30 years as the foreshock phenomena. While the Fermi-acceleration mechanism explains the diffuse component of foreshock ions, we still do not know the detailed mechanism that produces the discrete intense ions flowing along the local magnetic field direction (with and without gyration). One of the reasons for such difficulty is that majority of the bow shock study was performed for the Earth's case where Oxygen ions cannot be used to understand the acceleration mechanisms. The planetary oxygen ions that reach the Earth's bow shock have already been significantly accelerated, and are not adequate for such a study. In this sense the Martian bow shock is an ideal place to study the acceleration mechanisms leading to foreshock ions, although the nature of the bow shock is slightly different between the Earth and Mars (Yamauchi et al., 2011). On 21 September 2008, the Mars Express (MEX) Ion Mass Analyser (IMA) detected foreshock-like discrete distributions of oxygen ions at around 1 keV in the solar wind attached to the bow shock. This was the first time that a substantial amount of planetary oxygen was observed upstream of the bow shock. The oxygen energy increased from low energy (< 300 keV) inside the magnetosheath (or it should be called an extended bow shock) to nearly 2 keV at more than 2000 km from the bow shock. Foreshock-like protons are also observed but at a shifted location from the oxygen by about 1000 km, at a slightly higher energy, and flowing in a slightly different direction than the oxygen ions. Both protons and oxygen ions are flowing anti-sunward at different angles with respect to the solar wind direction. The observation is consistent with an electric potential barrier at the bow shock that simultaneously accelerates the planetary oxygen ions outward (to form the foreshock oxygen ions) and reflects a portion of the solar wind (to

  2. Direct current electric field assembly of colloidal crystals displaying reversible structural color.

    PubMed

    Shah, Aayush A; Ganesan, Mahesh; Jocz, Jennifer; Solomon, Michael J

    2014-08-26

    We report the application of low-voltage direct current (dc) electric fields to self-assemble close-packed colloidal crystals in nonaqueous solvents from colloidal spheres that vary in size from as large as 1.2 μm to as small as 0.1 μm. The assemblies are created rapidly (∼2 min) from an initially low volume fraction colloidal particle suspension using a simple capacitor-like electric field device that applies a steady dc electric voltage. Confocal microscopy is used to observe the ordering that is produced by the assembly method. This spatial evidence for ordering is consistent with the 6-fold diffraction patterns identified by light scattering. Red, green, and blue structural color is observed for the ordered assemblies of colloids with diameters of 0.50, 0.40, and 0.29 μm, respectively, consistent with spectroscopic measurements of reflectance. The diffraction and spectrophotometry results were found to be consistent with the theoretical Bragg's scattering expected for closed-packed crystals. By switching the dc electric field from on to off, we demonstrate reversibility of the structural color response on times scales ∼60 s. The dc electric field assembly method therefore represents a simple method to produce reversible structural color in colloidal soft matter.

  3. Direct measurement of depletion and hydrodynamic forces in solutions of a reversible supramolecular polymer.

    PubMed

    Knoben, W; Besseling, N A M; Stuart, M A Cohen

    2007-05-22

    In this paper, the investigation of surface forces in semidilute solutions of a nonadsorbing hydrogen-bonded reversible supramolecular polymer is described. Colloidal probe atomic force microscopy was used for direct measurement of depletion forces. Hydrodynamic drag on the AFM cantilever with the colloidal probe was measured both far away from and close to the planar substrate surface. The results indicate that the presence of the depletion layer causes slip at the surfaces with a large apparent slip length. Our analysis explains how the presence of slip enables the measurement of (relatively weak) depletion forces in solutions with a high viscosity by significantly reducing the hydrodynamic forces. The range and magnitude of the measured depletion forces are qualitatively in agreement with previous experiments and theoretical predictions. Due to the relatively large experimental error, no quantitative conclusions can be drawn. Depletion-induced phase separation of suspensions of stearylated silica particles was also observed. Phase separation becomes more pronounced with increasing polymer concentration.

  4. Bow-shaped toroidal field coils

    SciTech Connect

    Bonanos, P.

    1981-05-01

    Design features of Bow-Shaped Toroidal Field Coils are described and compared with circular and D shaped coils. The results indicate that bow coils can produce higher field strengths, store more energy and be made demountable. The design offers the potential for the production of ultrahigh toroidal fields. Included are representative coil shapes and their engineering properties, a suggested structural design and an analysis of a specific case.

  5. [Testing the reliability of face bow registration].

    PubMed

    Angyal, J; Keszthelyi, G

    1993-09-01

    The reliability of the Quick ear face-bow to transfer an arbitrary hinge axis to a Quick articulator was clinically compared with a Dentatus face-bow. 40 measurements were carried out on 8 patients with both instruments and were compared. The statistical analysis of the data indicated no difference between these facebow recordings. Furthermore both showed good reproducibility. This suggests that the same clinical results can be reached by these instruments.

  6. Extended red objects and stellar-wind bow shocks in the Carina Nebula

    NASA Astrophysics Data System (ADS)

    Sexton, Remington O.; Povich, Matthew S.; Smith, Nathan; Babler, Brian L.; Meade, Marilyn R.; Rudolph, Alexander L.

    2015-01-01

    We report the results of infrared photometry on 39 extended red objects (EROs) in the Carina Nebula, observed with the Spitzer Space Telescope. Most EROs are identified by bright, extended 8.0 μm emission, which ranges from 10 arcsec to 40 arcsec in size, but our sample also includes four EROs identified by extended 24 μm emission. Of particular interest are nine EROs associated with late O- or early B-type stars and characterized by arc-shaped morphology, suggesting dusty, stellar-wind bow shocks. These objects are preferentially oriented towards the central regions of the Carina Nebula, suggesting that these bow shocks are generally produced by the interactions of OB winds with the bulk expansion of the H II region rather than high proper motion. We identify preferred regions of mid-infrared colour space occupied by our bow shock candidates, which also contain bow shock candidates in M17 and RCW 49 but are well separated from polycyclic aromatic hydrocarbon emission or circumstellar discs. Colour cuts identify an additional 12 marginally resolved bow shock candidates, 10 of which are also associated with known late O or early B stars. H II region expansion velocities derived from bow shock candidate standoff distances are ˜10 km s-1, assuming typical H II region gas densities, comparable to expansion velocities derived from bow shocks in M17 and RCW 49. One candidate bow shock provides direct evidence of physical interaction between the massive stellar winds originating in the Trumpler 15 and Trumpler 14 clusters, supporting the conclusion that both clusters are at similar heliocentric distances.

  7. Reverse transcriptase directs viral evolution in a deep ocean methane seep

    NASA Astrophysics Data System (ADS)

    Paul, B. G.; Bagby, S. C.

    2013-12-01

    Deep ocean methane seeps are sites of intense microbial activity, with complex communities fueled by aerobic and anaerobic methanotrophy. Methane consumption in these communities has a substantial impact on the global carbon cycle, yet little is known about their evolutionary history or their likely evolutionary trajectories in a warming ocean. As in other marine systems, viral predation and virally mediated horizontal gene transfer are expected to be major drivers of evolutionary change in these communities; however, the host cells' resistance to cultivation has impeded direct study of the viral population. We conducted a metagenomic study of viruses in the anoxic sediments of a deep methane seep in the Santa Monica Basin in the Southern California Bight. We retrieved 1660 partial viral genomes, tentatively assigning 1232 to bacterial hosts and 428 to archaea. One abundant viral genome, likely hosted by Clostridia species present in the sediment, was found to encode a diversity-generating retroelement (DGR), a module for reverse transcriptase-mediated directed mutagenesis of a distal tail fiber protein. While DGRs have previously been described in the viruses of human pathogens, where diversification of viral tail fibers permits infection of a range of host cell types, to our knowledge this is the first description of such an element in a marine virus. By providing a mechanism for massively broadening potential host range, the presence of DGRs in these systems may have a major impact on the prevalence of virally mediated horizontal gene transfer, and even on the phylogenetic distances across which genes are moved.

  8. Planetary Embryo Bow Shocks as a Mechanism for Chondrule Formation

    NASA Astrophysics Data System (ADS)

    Mann, Christopher R.; Boley, Aaron C.; Morris, Melissa A.

    2016-02-01

    We use radiation hydrodynamics with direct particle integration to explore the feasibility of chondrule formation in planetary embryo bow shocks. The calculations presented here are used to explore the consequences of a Mars-size planetary embryo traveling on a moderately excited orbit through the dusty, early environment of the solar system. The embryo’s eccentric orbit produces a range of supersonic relative velocities between the embryo and the circularly orbiting gas and dust, prompting the formation of bow shocks. Temporary atmospheres around these embryos, which can be created via volatile outgassing and gas capture from the surrounding nebula, can non-trivially affect thermal profiles of solids entering the shock. We explore the thermal environment of solids that traverse the bow shock at different impact radii, the effects that planetoid atmospheres have on shock morphologies, and the stripping efficiency of planetoidal atmospheres in the presence of high relative winds. Simulations are run using adiabatic and radiative conditions, with multiple treatments for the local opacities. Shock speeds of 5, 6, and 7 km s-1 are explored. We find that a high-mass atmosphere and inefficient radiative conditions can produce peak temperatures and cooling rates that are consistent with the constraints set by chondrule furnace studies. For most conditions, the derived cooling rates are potentially too high to be consistent with chondrule formation.

  9. Planetary Embryo Bow Shocks as a Mechanism for Chondrule Formation

    NASA Astrophysics Data System (ADS)

    Mann, Christopher; Boley, Aaron C.; Morris, Melissa A.

    2015-01-01

    We investigate the plausibility of a planetary embryo bow shock as a mechanism for chondrule formation in the early solar system. A Mars-size planetary embryo traveling on a moderately excited orbit through the dusty early environment of the solar system will experience supersonic velocities relative to the circularly orbiting gas and dust. The resulting bow shock can thermally process solids that pass through it, with a wide range of possible conditions depending on impact radius. Volatile outgassing by the embryo along with some gas capture from the surrounding nebula can produce temporary atmospheres. We use radiation hydrodynamics simulations with direct particle integration to model the consequences of solids that encounter a bow shock produced by a 3000 km embryo with relative speeds to the gas of 5, 6, and 7 km/s. The embryos are envisaged to be surrounded by low- and high-mass atmospheres (0.75 and 6.25 Martian-mass atmospheres, respectively), and we explore different opacities for the gas. We find that a high-mass atmosphere and low dust opacity can produce peak temperatures and cooling rates that are most consistent with constraints set by chondrule furnace studies for plausible shock speeds.

  10. Characterising the Canine Oral Microbiome by Direct Sequencing of Reverse-Transcribed rRNA Molecules.

    PubMed

    McDonald, James E; Larsen, Niels; Pennington, Andrea; Connolly, John; Wallis, Corrin; Rooks, David J; Hall, Neil; McCarthy, Alan J; Allison, Heather E

    2016-01-01

    PCR amplification and sequencing of phylogenetic markers, primarily Small Sub-Unit ribosomal RNA (SSU rRNA) genes, has been the paradigm for defining the taxonomic composition of microbiomes. However, 'universal' SSU rRNA gene PCR primer sets are likely to miss much of the diversity therein. We sequenced a library comprising purified and reverse-transcribed SSU rRNA (RT-SSU rRNA) molecules from the canine oral microbiome and compared it to a general bacterial 16S rRNA gene PCR amplicon library generated from the same biological sample. In addition, we have developed BIONmeta, a novel, open-source, computer package for the processing and taxonomic classification of the randomly fragmented RT-SSU rRNA reads produced. Direct RT-SSU rRNA sequencing revealed that 16S rRNA molecules belonging to the bacterial phyla Actinobacteria, Bacteroidetes, Firmicutes, Proteobacteria and Spirochaetes, were most abundant in the canine oral microbiome (92.5% of total bacterial SSU rRNA). The direct rRNA sequencing approach detected greater taxonomic diversity (1 additional phylum, 2 classes, 1 order, 10 families and 61 genera) when compared with general bacterial 16S rRNA amplicons from the same sample, simultaneously provided SSU rRNA gene inventories of Bacteria, Archaea and Eukarya, and detected significant numbers of sequences not recognised by 'universal' primer sets. Proteobacteria and Spirochaetes were found to be under-represented by PCR-based analysis of the microbiome, and this was due to primer mismatches and taxon-specific variations in amplification efficiency, validated by qPCR analysis of 16S rRNA amplicons from a mock community. This demonstrated the veracity of direct RT-SSU rRNA sequencing for molecular microbial ecology. PMID:27276347

  11. Characterising the Canine Oral Microbiome by Direct Sequencing of Reverse-Transcribed rRNA Molecules

    PubMed Central

    McDonald, James E.; Larsen, Niels; Pennington, Andrea; Connolly, John; Wallis, Corrin; Rooks, David J.; Hall, Neil; McCarthy, Alan J.; Allison, Heather E.

    2016-01-01

    PCR amplification and sequencing of phylogenetic markers, primarily Small Sub-Unit ribosomal RNA (SSU rRNA) genes, has been the paradigm for defining the taxonomic composition of microbiomes. However, ‘universal’ SSU rRNA gene PCR primer sets are likely to miss much of the diversity therein. We sequenced a library comprising purified and reverse-transcribed SSU rRNA (RT-SSU rRNA) molecules from the canine oral microbiome and compared it to a general bacterial 16S rRNA gene PCR amplicon library generated from the same biological sample. In addition, we have developed BIONmeta, a novel, open-source, computer package for the processing and taxonomic classification of the randomly fragmented RT-SSU rRNA reads produced. Direct RT-SSU rRNA sequencing revealed that 16S rRNA molecules belonging to the bacterial phyla Actinobacteria, Bacteroidetes, Firmicutes, Proteobacteria and Spirochaetes, were most abundant in the canine oral microbiome (92.5% of total bacterial SSU rRNA). The direct rRNA sequencing approach detected greater taxonomic diversity (1 additional phylum, 2 classes, 1 order, 10 families and 61 genera) when compared with general bacterial 16S rRNA amplicons from the same sample, simultaneously provided SSU rRNA gene inventories of Bacteria, Archaea and Eukarya, and detected significant numbers of sequences not recognised by ‘universal’ primer sets. Proteobacteria and Spirochaetes were found to be under-represented by PCR-based analysis of the microbiome, and this was due to primer mismatches and taxon-specific variations in amplification efficiency, validated by qPCR analysis of 16S rRNA amplicons from a mock community. This demonstrated the veracity of direct RT-SSU rRNA sequencing for molecular microbial ecology. PMID:27276347

  12. Direct measurement of depletion and hydrodynamic forces in solutions of a reversible supramolecular polymer.

    PubMed

    Knoben, W; Besseling, N A M; Stuart, M A Cohen

    2007-05-22

    In this paper, the investigation of surface forces in semidilute solutions of a nonadsorbing hydrogen-bonded reversible supramolecular polymer is described. Colloidal probe atomic force microscopy was used for direct measurement of depletion forces. Hydrodynamic drag on the AFM cantilever with the colloidal probe was measured both far away from and close to the planar substrate surface. The results indicate that the presence of the depletion layer causes slip at the surfaces with a large apparent slip length. Our analysis explains how the presence of slip enables the measurement of (relatively weak) depletion forces in solutions with a high viscosity by significantly reducing the hydrodynamic forces. The range and magnitude of the measured depletion forces are qualitatively in agreement with previous experiments and theoretical predictions. Due to the relatively large experimental error, no quantitative conclusions can be drawn. Depletion-induced phase separation of suspensions of stearylated silica particles was also observed. Phase separation becomes more pronounced with increasing polymer concentration. PMID:17439251

  13. Neural correlates of spontaneous direction reversals in ambiguous apparent visual motion.

    PubMed

    Sterzer, Philipp; Russ, Michael O; Preibisch, Christine; Kleinschmidt, Andreas

    2002-04-01

    Looking at bistable visual stimuli, the observer experiences striking transitions between two competing percepts while the physical stimulus remains the same. Using functional imaging techniques, it is therefore possible to isolate neural correlates of perceptual changes that are independent of the low-level aspects of the stimulus. Previous experiments have demonstrated distributed activations in human extrastriate visual cortex related to switches between competing percepts. Here we asked where extrastriate responses still occur with a bistable stimulus that minimizes the cognitive difference between the two percepts. We used the "spinning wheel illusion," a bistable apparent motion stimulus of which both possible percepts correspond to the same object, share the same center, and are perceived as identically patterned stimuli moving at the same speed and changing only in direction. Using functional magnetic resonance imaging, we analyzed the spatial distribution of event-related activations occurring during spontaneous reversals of perceived direction of motion. In accordance with earlier neuroimaging findings for bistable percepts, we observed event-related activations in several frontal and parietal areas, including the superior parietal cortex bilaterally, the right inferior parietal cortex, and the premotor and inferior frontal cortex of both hemispheres. Furthermore, we found bilateral activations in the occipitotemporal junction (hMT+/V5) and in the lateral occipital sulcus ("KO") posterior to hMT+/V5, but not in areas of the "ventral stream" of cortical visual processing. Our data suggest that, while a frontoparietal network subserves more general aspects in bistable visual perception, the activations in functionally specialized extrastriate visual cortex are highly category- or attribute-specific.

  14. Upstream particle events close to the bow shock and 200 earth radii upstream - ISEE-1 and ISEE-3 observations

    NASA Technical Reports Server (NTRS)

    Scholer, M.; Hovestadt, D.; Klecker, B.; Ipavich, F. M.; Gloeckler, G.

    1980-01-01

    Two energetic particle events (28 keV - 145 keV) upstream of the earth's bow shock have been investigated with two identical experiments of the Max-Planck-Institut/University of Maryland on ISEE-1 and ISEE-3. Close to the bow shock the particle distribution is more or less isotropic and indicates strong scattering of these particles in the upstream wave field. At ISEE-3 the particles move essentially scatter-free from the general bow shock direction. The temporal evolution of the particle bursts is discussed in terms of the interplanetary magnetic field topology and the scattering conditions.

  15. Comparison of accelerated ion populations observed upstream of the bow shocks at Venus and Mars

    NASA Astrophysics Data System (ADS)

    Yamauchi, M.; Futaana, Y.; Fedorov, A.; Frahm, R. A.; Winningham, J. D.; Dubinin, E.; Lundin, R.; Barabash, S.; Holmström, M.; Mazelle, C.; Sauvaud, J.-A.; Zhang, T. L.; Baumjohann, W.; Coates, A. J.; Fraenz, M.

    2011-03-01

    Foreshock ions are compared between Venus and Mars at energies of 0.6~20 keV using the same ion instrument, the Ion Mass Analyser, on board both Venus Express and Mars Express. Venus Express often observes accelerated protons (2~6 times the solar wind energy) that travel away from the Venus bow shock when the spacecraft location is magnetically connected to the bow shock. The observed ions have a large field-aligned velocity compared to the perpendicular velocity in the solar wind frame, and are similar to the field-aligned beams and intermediate gyrating component of the foreshock ions in the terrestrial upstream region. Mars Express does not observe similar foreshock ions as does Venus Express, indicating that the Martian foreshock does not possess the intermediate gyrating component in the upstream region on the dayside of the planet. Instead, two types of gyrating protons in the solar wind frame are observed very close to the Martian quasi-perpendicular bow shock within a proton gyroradius distance. The first type is observed only within the region which is about 400 km from the bow shock and flows tailward nearly along the bow shock with a similar velocity as the solar wind. The second type is observed up to about 700 km from the bow shock and has a bundled structure in the energy domain. A traversal on 12 July 2005, in which the energy-bunching came from bundling in the magnetic field direction, is further examined. The observed velocities of the latter population are consistent with multiple specular reflections of the solar wind at the bow shock, and the ions after the second reflection have a field-aligned velocity larger than that of the de Hoffman-Teller velocity frame, i.e., their guiding center has moved toward interplanetary space out from the bow shock. To account for the observed peculiarity of the Martian upstream region, finite gyroradius effects of the solar wind protons compared to the radius of the bow shock curvature and effects of cold ion

  16. Solar cycle variations in the neutral exosphere inferred from the location of the Venus bow shock

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Chou, E.; Luhmann, J. G.; Brace, L. H.

    1990-01-01

    Solar UV and EUV varies significantly during the solar cycle. Pioneer Venus can measure this variation both directly and indirectly. A direct measure of the EUV is obtained from the photoelectron current of the Langmuir probe when the spacecraft is in the solar wind. The indirect measure is by monitoring the location of the Venus bow shock. The UV and EUV both heat the upper atmosphere and ionize it. When solar activity is high, the upper atmosphere should be ionized more rapidly. This effect adds a greater number of planetary ions to the magnetosheath plasma as it flows by Venus. It is this increase in mass flow that causes the Venus bow shock to move away from its solar minimum location. Pioneer Venus has now monitored the location of the bow shock for an entire solar cycle. The bow shock location is well correlated with the variation in EUV flux as measured by the Langmuir probe. The bow shock is farther from Venus than expected from the sunspot number or 10.7 cm solar radio flux, indicating that solar UV radiation may be even stronger at the present time than would be predicted from the relationships determined during the previous solar cycle.

  17. Multispacecraft observations of energetic ions upstream and downstream of the bow shock

    SciTech Connect

    Scholer, M.; Mobius, E.; Kistler, L. M.; Klecker, B.; Ipavich, F. M.

    1989-06-01

    We present simultaneous measurements of energetic protons and alpha particles inside and outside of the magnetopause, immediately upstream, and downstream as well as further upstream of the bow shock. A comparison between the intensity at the bow shock and further upstream results in an e-folding distance at 30 keV of /similar to/6.2 R/sub E/. After transformation of the angular distribution into the solar wind frame a diffusion coefficeint of kappa/sub /parallel///similar to/3 R/sub E/ is obtained from the anisotropy and the intensity gradient. Immediately downstream of the bow shock the anisotropy in the shock frame is directed toward the magnetopause. After transformation into the plasma rest frame the distribution is isotropic. The intensity in the magnetosheath just outside the magnetopause is smaller than the intensity behind the bow shock. Thus, in the magnetosheath there is no gradient or streaming in the upstream direction. The spectra, intensities, and relative abundances in the magnetosheath and inside the magnetosphere are totally different. These observations are consistent with first order Fermi acceleration at the bow shock and subsequent downstream convection, and exclude a magnetospheric source for these particles. /copyright/ American Geophysical Union 1989

  18. The return of the bow shock

    SciTech Connect

    Scherer, K.; Fichtner, H. E-mail: hf@tp4.rub.de

    2014-02-10

    Recently, whether a bow shock ahead of the heliospheric stagnation region exists or not has been a topic of discussion. This was triggered by measurements indicating that the Alfvén speed and the speed of fast magnetosonic waves are higher than the flow speed of the local interstellar medium (LISM) relative to the heliosphere and resulted in the conclusion that either a bow wave or a slow magnetosonic shock might exist. We demonstrate here that including the He{sup +} component of the LISM yields both an Alfvén and fast magnetosonic wave speed lower than the LISM flow speed. Consequently, the scenario of a bow shock in front of the heliosphere, as modeled in numerous simulations of the interaction of the solar wind with the LISM, remains valid.

  19. An analytic treatment of the structure of the bow shock and magnetosheath

    NASA Technical Reports Server (NTRS)

    Zhuang, H. C.; Russell, C. T.

    1981-01-01

    A theoretical examination of the jump conditions of the bow shock is used to investigate the influence of the solar wind magnetic fields on the structure of the parameters behind the bow shock. Through the assumption that the average values of the parameters along the radial direction in the magnetosheath are equal to their values just behind the bow shock, the influence of the direction of the solar wind magnetic fields on the average structure of the magnetosheath is determined. From this assumption, a zero-order formula for the thickness of the magnetosheath is deduced which satisfies the boundary conditions and conservation laws of mass and momentum flux. The theoretical estimate of the thickness is compared with satellite observations to check the assumption and select the optimum value of the polytropic exponent of the plasma gas.

  20. Energetic interplanetary nucleon flux anisotropies - The effect of earth's bow shock and magnetosheath on sunward flow

    NASA Technical Reports Server (NTRS)

    Christon, S. P.

    1982-01-01

    Attention is given to the combined, average effects of the bow shock and magnetosheath on the diffusive flow of interplanetary nuclei. The observations presented show that differences between 'connected' and 'unconnected' data subsets are apparent from the beginning of the analysis. Through an investigation of the mean unconnected diffusive anisotropy (those fluxes least affected by the earth's bow shock and magnetosheath) it is confirmed that the cross-field transport of MeV energy nuclei in interplanetary space is statistically significant and in the direction expected from the large-scale particle flux gradients. The direction of particle flow relative to the IMF is then used to show that nucleon flow characteristics on connected IMF differ from those on unconnected IMF. A scenario for producing this difference is then presented. It is concluded that the inclusion of the bow shock connected information biases measurements of the flux anisotropies of MeV energy H.

  1. The Enzyme-Mediated Direct Reversal of a Dithymine Photoproduct in Germinating Endospores

    PubMed Central

    Yang, Linlin; Li, Lei

    2013-01-01

    Spore photoproduct lyase (SPL) repairs a special thymine dimer, 5-thyminyl-5,6-dihydrothymine, which is commonly called spore photoproduct, or SP, in germinating endospores. SP is the exclusive DNA photo-damaging product found in endospores; its generation and swift repair by SPL are responsible for the spores’ extremely high UV resistance. Early in vivo studies suggested that SPL utilizes a direct reversal strategy to repair SP in the absence of light. Recently, it has been established that SPL belongs to the radical S-adenosylmethionine (SAM) superfamily. The enzymes in this superfamily utilize a tri-cysteine CXXXCXXC motif to bind a [4Fe-4S] cluster. The cluster provides an electron to the S-adenosylmethionine (SAM) to reductively cleave its C5′-S bond, generating a reactive 5′-deoxyadenosyl (5′-dA) radical. This 5′-dA radical abstracts the proR hydrogen atom from the C6 carbon of SP to initiate the repair process; the resulting SP radical subsequently fragments to generate a putative thymine methyl radical, which accepts a back-donated H atom to yield the repaired TpT. The H atom donor is suggested to be a conserved cysteine141 in B. subtilis SPL; the resulting thiyl radical likely interacts with a neighboring tyrosine99 before oxidizing the 5′-dA to 5′-dA radical and, subsequently, regenerating SAM. These findings suggest SPL to be the first enzyme in the large radical SAM superfamily (>44,000 members) to utilize a radical transfer pathway for catalysis; its study should shed light on the mechanistic understanding of the SAM regeneration process in other members of the superfamily. PMID:23799365

  2. Large amplitude MHD waves upstream of the Jovian bow shock

    NASA Technical Reports Server (NTRS)

    Goldstein, M. L.; Smith, C. W.; Matthaeus, W. H.

    1983-01-01

    Observations of large amplitude magnetohydrodynamics (MHD) waves upstream of Jupiter's bow shock are analyzed. The waves are found to be right circularly polarized in the solar wind frame which suggests that they are propagating in the fast magnetosonic mode. A complete spectral and minimum variance eigenvalue analysis of the data was performed. The power spectrum of the magnetic fluctuations contains several peaks. The fluctuations at 2.3 mHz have a direction of minimum variance along the direction of the average magnetic field. The direction of minimum variance of these fluctuations lies at approximately 40 deg. to the magnetic field and is parallel to the radial direction. We argue that these fluctuations are waves excited by protons reflected off the Jovian bow shock. The inferred speed of the reflected protons is about two times the solar wind speed in the plasma rest frame. A linear instability analysis is presented which suggests an explanation for many of the observed features of the observations.

  3. 1. View looking south on Montana Street. The Silver Bow ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View looking south on Montana Street. The Silver Bow County Courthouse (1910-1912) is on the left. - Butte Historic District, Bounded by Copper, Arizona, Mercury & Continental Streets, Butte, Silver Bow County, MT

  4. 2. VIEW NORTH OF BOW OF JFK IN DRYDOCK NO. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW NORTH OF BOW OF JFK IN DRYDOCK NO. 5; NOTE BOW ANCHOR AT TOP CENTER. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Dry Dock No. 5, League Island, Philadelphia, Philadelphia County, PA

  5. Structuration in the Interface of Direct and Reversed Micelles of Sucrose Esters, Studied by Fluorescent Techniques

    PubMed Central

    Sandoval, Catalina; Ortega, Anakenna; Sanchez, Susana A.; Morales, Javier; Gunther, German

    2015-01-01

    Background Reactors found in nature can be described as micro-heterogeneous systems, where media involved in each micro-environment can behave in a markedly different way compared with the properties of the bulk solution. The presence of water molecules in micro-organized assemblies is of paramount importance for many chemical processes, ranging from biology to environmental science. Self-organized molecular assembled systems are frequently used to study dynamics of water molecules because are the simplest models mimicking biological membranes. The hydrogen bonds between sucrose and water molecules are described to be stronger (or more extensive) than the ones between water molecules themselves. In this work, we studied the capability of sucrose moiety, attached to alkyl chains of different length, as a surface blocking agent at the water-interface and we compared its properties with those of polyethylenglycol, a well-known agent used for this purposes. Published studies in this topic mainly refer to the micellization process and the stability of mixed surfactant systems using glycosides. We are interested in the effect induced by the presence of sucrose monoesters at the interface (direct and reverse micelles) and at the palisade (mixtures with Triton X-100). We believe that the different functional group (ester), the position of alkyl chain (6-O) and the huge capability of sucrose to interact with water will dramatically change the water structuration at the interface and at the palisade, generating new possibilities for technological applications of these systems. Results Our time resolved and steady state fluorescence experiments in pure SEs micelles show that sucrose moieties are able to interact with a high number of water molecules promoting water structuration and increased viscosity. These results also indicate that the barrier formed by sucrose moieties on the surface of pure micelles is more effective than the polyoxyethylene palisade of Triton X-100

  6. Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase-Cas1 fusion protein.

    PubMed

    Silas, Sukrit; Mohr, Georg; Sidote, David J; Markham, Laura M; Sanchez-Amat, Antonio; Bhaya, Devaki; Lambowitz, Alan M; Fire, Andrew Z

    2016-02-26

    CRISPR systems mediate adaptive immunity in diverse prokaryotes. CRISPR-associated Cas1 and Cas2 proteins have been shown to enable adaptation to new threats in type I and II CRISPR systems by the acquisition of short segments of DNA (spacers) from invasive elements. In several type III CRISPR systems, Cas1 is naturally fused to a reverse transcriptase (RT). In the marine bacterium Marinomonas mediterranea (MMB-1), we showed that a RT-Cas1 fusion protein enables the acquisition of RNA spacers in vivo in a RT-dependent manner. In vitro, the MMB-1 RT-Cas1 and Cas2 proteins catalyze the ligation of RNA segments into the CRISPR array, which is followed by reverse transcription. These observations outline a host-mediated mechanism for reverse information flow from RNA to DNA. PMID:26917774

  7. Direct integration of MEMS, dielectric pumping and cell manipulation with reversibly bonded gecko adhesive microfluidics

    NASA Astrophysics Data System (ADS)

    Warnat, S.; King, H.; Wasay, A.; Sameoto, D.; Hubbard, T.

    2016-09-01

    We present an approach to form a microfluidic environment on top of MEMS dies using reversibly bonded microfluidics. The reversible polymeric microfluidics moulds bond to the MEMS die using a gecko-inspired gasket architecture. In this study the formed microchannels are demonstrated in conjunction with a MEMS mechanical single cell testing environment for BioMEMS applications. A reversible microfluidics placement technique with an x-y and rotational accuracy of  ±2 µm and 1° respectively on a MEMS die was developed. No leaks were observed during pneumatic pumping of common cell media (PBS, sorbitol, water, seawater) through the fluidic channels. Thermal chevron actuators were successful operated inside this fluidic environment and a performance deviation of ~15% was measured compared to an open MEMS configuration. Latex micro-spheres were pumped using traveling wave di-electrophoresis and compared to an open (no-microfluidics) configuration with velocities of 24 µm s‑1 and 20 µm s‑1.

  8. Direct CRISPR spacer acquisition from RNA by a natural reverse-transcriptase-Cas1 fusion protein

    PubMed Central

    Sidote, David J.; Markham, Laura M.; Sanchez-Amat, Antonio; Bhaya, Devaki; Lambowitz, Alan M.; Fire, Andrew Z.

    2016-01-01

    CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat) systems mediate adaptive immunity in diverse prokaryotes. CRISPR-associated Cas1 and Cas2 proteins have been shown to enable adaptation to new threats in Type I and II CRISPR systems by the acquisition of short segments of DNA (“spacers”) from invasive elements. In several Type III CRISPR systems, Cas1 is naturally fused to a reverse transcriptase (RT). In the marine bacterium Marinomonas mediterranea (MMB-1), we show that an RT-Cas1 fusion enables the acquisition of RNA spacers in vivo in an RT-dependent manner. In vitro, the MMB-1 RT-Cas1 and Cas2 proteins catalyze ligation of RNA segments into the CRISPR array, followed by reverse transcription. These observations outline a host-mediated mechanism for reverse information flow from RNA to DNA. PMID:26917774

  9. Direct integration of MEMS, dielectric pumping and cell manipulation with reversibly bonded gecko adhesive microfluidics

    NASA Astrophysics Data System (ADS)

    Warnat, S.; King, H.; Wasay, A.; Sameoto, D.; Hubbard, T.

    2016-09-01

    We present an approach to form a microfluidic environment on top of MEMS dies using reversibly bonded microfluidics. The reversible polymeric microfluidics moulds bond to the MEMS die using a gecko-inspired gasket architecture. In this study the formed microchannels are demonstrated in conjunction with a MEMS mechanical single cell testing environment for BioMEMS applications. A reversible microfluidics placement technique with an x-y and rotational accuracy of  ±2 µm and 1° respectively on a MEMS die was developed. No leaks were observed during pneumatic pumping of common cell media (PBS, sorbitol, water, seawater) through the fluidic channels. Thermal chevron actuators were successful operated inside this fluidic environment and a performance deviation of ~15% was measured compared to an open MEMS configuration. Latex micro-spheres were pumped using traveling wave di-electrophoresis and compared to an open (no-microfluidics) configuration with velocities of 24 µm s-1 and 20 µm s-1.

  10. How the bow shock does it

    NASA Astrophysics Data System (ADS)

    Omidi, N.

    1995-07-01

    Between the world of living organisms and inanimate objects exists a zone inhabited by animate, but nonliving, physical entities. These fascinating, and often nonlinear systems exhibit characteristics which in many ways mimic that of simple biological organisms. They seem to have an instinctive desire to accomplish certain tasks, and devise many creative strategies to achieve their goal. The bow shock, the topic of this paper, is one of the inhabitants of this zone and it forms due to solar wind interaction with the Earth's magnetic field. As one would expect, its goal is to decelerate and divert the supersonic solar wind flow around the magnetosphere. But unlike the usual shock waves, it has to accomplish the task without the use of collisions; quite a challenge indeed. A bigger challenge, however, has been for us to use space age technology and supercomputers to find out how the bow shock does it! We have made much progress; many of the pixels are in place but the picture is not complete. What we have found is a truly fascinating and complex story which is a testament to the creativeness of the bow shock. Depending on the upstream Mach number (ratio of the solar wind speed to the sound speed) and location on the paraboloid surface of the shock, a different strategy for dissipation of the flow energy into heat is utilized. In some regimes, the transition from upstream to downstream takes place on short ( ˜100 km) length scales, while in others, the shock transition is masked with an extended region of electromagnetic waves and turbulence. As part of the dissipation process, electrons and ions are reflected off the shock. The interaction between the solar wind and the reflected particles forms the foreshock, a region extending many Earth radii upstream of the shock. The foreshock is populated by a variety of electrostatic and electromagnetic waves, making it a great natural laboratory for studies of nonlinear wave-particle interactions. Among these are the fast

  11. Observations of low-energy electrons upstream of the earth's bow shock

    NASA Technical Reports Server (NTRS)

    Reasoner, D. L.

    1974-01-01

    Observations of electron fluxes with a lunar-based electron spectrometer when the moon was upstream of the earth have shown that a subset of observed fluxes are strongly controlled by the interplanetary magnetic field direction. The fluxes occur only when the IMF lines connect back to the earth's bow shock. Observed densities and temperatures were in the ranges 2-4 x 0,001/cu cm and 1.7-2.8 x 1,000,000 K. It is shown that these electrons can account for increases in effective solar wind electron temperatures on bow-shock connected field lines which have been observed previously by other investigators. It is further shown that if a model of the bow shock with an electrostatic potential barrier is assumed, the potential can be estimated to be 500 volts.

  12. Effects of the bow on social organization in Western North America.

    PubMed

    Bettinger, Robert L

    2013-01-01

    The bow more than doubled, likely tripled, the success of individuals bent on killing animal or human targets (Box ). The advent of this revolutionary technology generated different responses in western North America depending on subsistence and sociopolitical organization at the time of its arrival, roughly 2300 - 1300 B.P. Its effect was substantial in California and the Great Basin, particularly on group size, which in many places diminished as a consequence of the bow's reliability. The counter-intuitive result was to increase within group-relatedness enough to encourage intensification of plant resources, previously considered too costly. The bow rose to greatest direct economic importance with the arrival of the horse, and was put to most effective use by former Great Basin groups who maintained the family band system that had developed around intensive Great Basin plant procurement, adapting the same organization to a lifestyle centered on the equestrian pursuit of buffalo and warfare.

  13. Effects of the bow on social organization in Western North America.

    PubMed

    Bettinger, Robert L

    2013-01-01

    The bow more than doubled, likely tripled, the success of individuals bent on killing animal or human targets (Box ). The advent of this revolutionary technology generated different responses in western North America depending on subsistence and sociopolitical organization at the time of its arrival, roughly 2300 - 1300 B.P. Its effect was substantial in California and the Great Basin, particularly on group size, which in many places diminished as a consequence of the bow's reliability. The counter-intuitive result was to increase within group-relatedness enough to encourage intensification of plant resources, previously considered too costly. The bow rose to greatest direct economic importance with the arrival of the horse, and was put to most effective use by former Great Basin groups who maintained the family band system that had developed around intensive Great Basin plant procurement, adapting the same organization to a lifestyle centered on the equestrian pursuit of buffalo and warfare. PMID:23776048

  14. Conditions for acceleration of energetic ions greater than 30 keV associated with the earth's bow shock

    NASA Technical Reports Server (NTRS)

    Scholer, M.; Hovestadt, D.; Ipavich, F. M.; Gloeckler, G.

    1980-01-01

    A statistical analysis of particles (greater than 30 keV/charge) upstream of the earth's bow shock is conducted and shows that the rate of occurrence of upstream particle events is relative to the angle between the magnetic field and the shock normal at the shock intersection point as well as relative to the angle between the magnetic field and the radial direction (i.e., the sun-earth line). In addition, the occurrence rate of upstream particle events relative to the bow shock connection time of a field line convected with the solar wind is presented for a model bow shock. A linear dependence of the diffusion coefficient on energy per charge is apparent with the value of the mean free path of a 30-keV proton found to be about 4 earth radii, and the free escape boundary to be at about 30 earth radii in front of the bow shock.

  15. A Theoretical Exploration of the Differences between Prompt and Bow Shock Initiation of Explosives by Shaped Charge Jets

    NASA Astrophysics Data System (ADS)

    Mellor, Christopher; James, Hugh; Goff, Michael

    2011-06-01

    The use of the CREST reactive burn model in conjunction with results from the open literature demonstrates the differences between prompt and bow shock initiation, even when the diameter of the shaped charge jet is much larger than the failure diameter of the explosive. The burn model shows the need for the bow shock to build in strength before reaching an amplitude where significant reaction is triggered, and hence explains the observed very long runs to detonation required by this mechanism. While the compression of the explosive between the bow shock and the jet provides much greater pressures than those seen in the bow shock, the relative thermodynamic inefficiency of the compression process means that this region contributes little to the direct generation of reaction.

  16. Influence of Additive and Multiplicative Structure and Direction of Comparison on the Reversal Error

    ERIC Educational Resources Information Center

    González-Calero, José Antonio; Arnau, David; Laserna-Belenguer, Belén

    2015-01-01

    An empirical study has been carried out to evaluate the potential of word order matching and static comparison as explanatory models of reversal error. Data was collected from 214 undergraduate students who translated a set of additive and multiplicative comparisons expressed in Spanish into algebraic language. In these multiplicative comparisons…

  17. Properties of bow-shock sources at the Galactic center

    NASA Astrophysics Data System (ADS)

    Sanchez-Bermudez, J.; Schödel, R.; Alberdi, A.; Muzić, K.; Hummel, C. A.; Pott, J.-U.

    2014-07-01

    Context. There exists an enigmatic population of massive stars around the Galactic center (GC) that were formed some Myr ago. A fraction of these stars has been found to orbit the supermassive black hole, Sgr A*, in a projected clockwise disk-like structure, which suggests that they were formed in a formerly existing dense disk around Sgr A*. Aims: We focus on a subgroup of objects, the extended, near-infrared (NIR) bright sources IRS 1W, IRS 5, IRS 10W, and IRS 21, that have been suggested to be young, massive stars that form bow shocks through their interaction with the interstellar medium (ISM). Their nature has impeded accurate determinations of their orbital parameters. We aim at establishing their nature and kinematics to test whether they form part of the clockwise disk. Methods: We performed NIR multiwavelength imaging with NACO/VLT using direct adaptive optics (AO) and AO-assisted sparse aperture masking (SAM). We introduce a new method for self-calibration of the SAM point spread function in dense stellar fields. The emission mechanism, morphology, and kinematics of the targets were examined via 3D models, combined with existing models of the gas flow in the central parsec. Results: We confirm previous findings that IRS 21, IRS 1W, and IRS 5 are bow-shocks created by the interaction between mass-losing stars and the interstellar gas. The nature of IRS 10W remains unclear. Our modeling shows that the bow-shock emission is caused by thermal emission, while the scattering of stellar light does not play a significant role. IRS 1W shows a morphology that is consistent with a bow shock produced by an anisotropic stellar wind or by locally inhomogeneous ISM density. Our best-fit models provide estimates of the local proper motion of the ISM in the Northern Arm that agree with previously published models that were based on radio interferometry and NIR spectroscopy. Assuming that all of the sources are gravitationally tied to Sagittarius A*, their orbital planes

  18. Power aspects of processes in the bow shock region

    NASA Astrophysics Data System (ADS)

    Sedykh, Pavel

    Bow shock is a powerful transformer of the solar wind kinetic energy into the gas dynamic and electromagnetic energy. The solar wind energy also feeds the ion acceleration process, the generation of waves in the region of bow shock, and the energy necessary to build up the foreshock. A jump of the magnetic field tangential component at front crossing means that the front carries an electric current. The solar wind kinetic energy partly transforms to gas kinetic and electromagnetic energy during its passage through the bow shock front. The transition layer (magnetosheath) can use part of this energy for accelerating of plasma, but can conversely spend part its kinetic energy on the electric power generation, which afterwards may be used by the magnetosphere. Thereby, transition layer can be both consumer (sink) and generator (source) of electric power depending upon special conditions. The direction of the current behind the bow shock front depends on the sign of the IMF B _{z}-component. It is this electric current which sets convection of plasma in motion. The process of current penetration into the magnetosphere is two-step. First, a polarization field is formed that penetrates layer-by-layer into the magnetosphere. More exactly, a pulse corresponding to this field penetrates into the plasma. Then, if the system is inhomogeneous, the flow may redistribute the pressure so that gradients appearing in the plasma induce an electric current. In power terms, this electric current is required to maintain convection in the inhomogeneous system. Any change in the external current through the magnetosphere causes a convection restructuring within a time on the order of travel time of the magnetosonic wave from the magnetopause to the center of the system, because the restructuring wave comes from both flanks. Using the expressions obtained in this paper for normal components of the electric current, the flow of matter brought into the magnetosphere can be estimated. A

  19. A BOW SHOCK NEAR A YOUNG STAR

    NASA Technical Reports Server (NTRS)

    2002-01-01

    NASA's Hubble Space Telescope continues to reveal various stunning and intricate treasures that reside within the nearby, intense star-forming region known as the Great Nebula in Orion. One such jewel is the bow shock around the very young star, LL Ori, featured in this Hubble Heritage image. Named for the crescent-shaped wave made by a ship as it moves through water, a bow shock can be created in space when two streams of gas collide. LL Ori emits a vigorous solar wind, a stream of charged particles moving rapidly outward from the star. Our own Sun has a less energetic version of this wind that is responsible for auroral displays on the Earth. The material in the fast wind from LL Ori collides with slow-moving gas evaporating away from the center of the Orion Nebula, which is located to the lower right in this Heritage image. The surface where the two winds collide is the crescent-shaped bow shock seen in the image. Unlike a water wave made by a ship, this interstellar bow shock is a three-dimensional structure. The filamentary emission has a very distinct boundary on the side facing away from LL Ori, but is diffuse on the side closest to the star, a characteristic common to many bow shocks. A second, fainter bow shock can be seen around a star near the upper right-hand corner of the Heritage image. Astronomers have identified numerous shock fronts in this complex star-forming region and are using this data to understand the many complex phenomena associated with the birth of stars. This image was taken in February 1995 as part of the Hubble Orion Nebula mosaic. A close visitor in our Milky Way galaxy, the nebula is only 1,500 light-years from Earth. The filters used in this color composite represent oxygen, nitrogen, and hydrogen emissions. Image Credit: NASA and the Hubble Heritage Team (STScI/AURA) Acknowledgment: C. R. O'Dell (Vanderbilt University)

  20. Horizontal-plane arm movements with direction reversals performed by normal individuals and individuals with down syndrome.

    PubMed

    Almeida, G L; Corcos, D M; Hasan, Z

    2000-10-01

    We examined the systematic variation in shoulder and elbow torque, as well as movement kinematics, for horizontal-plane arm movements with direction reversals performed by normal individuals and individuals with Down syndrome. Eight neurologically normal individuals and eight individuals with Down syndrome performed horizontal, planar reversal movements to four different target locations. The four locations of the targets were chosen such that there is a systematic increase in elbow interaction torque for each of the four different target locations. This systematic increase in interaction torque has previously been shown to lead to progressively larger movement reversal errors, and trajectories that do not show a sharp reversal of direction, for movements to and from the target in patients who have proprioceptive abnormalities. We computed joint torques at the elbow and shoulder and found a high correlation between elbow and shoulder torque for the neurologically normal subjects. The ratio of joint torques varied systematically with target location. These findings extend previously reported findings of a linear synergy between shoulder and elbow joints for a variety of point-to-point movements. There was also a correlation between elbow and shoulder torque in individuals with Down syndrome, but the magnitude of the correlation was less. The ratio of joint torques changed systematically with target direction in individuals with Down syndrome but was slightly different from the ratio observed for neurologically normal individuals. The difference in the ratio was caused by the generation of proportionately more elbow torque than shoulder torque. The fingertip path of individuals with Down syndrome showed a sharp reversal in moving toward and then away from the target. In this respect, they were similar to neurologically normal individuals but dissimilar to individuals with proprioceptive deficits. Finally, we observed that individuals with Down syndrome spend

  1. Energetic Electrons as Evidence for a Bow Shock at Ceres

    NASA Astrophysics Data System (ADS)

    Villarreal, Michaela; Russell, Christopher; Prettyman, Thomas; Yamashita, Naoyuki; Jia, Ying Dong; Chi, Peter; Joy, Steven

    2016-04-01

    In late June 2016 when Dawn was in its Survey orbit around Ceres, the +Z Phoswich scintillator aboard GRaND (Gamma Ray and Neutron Detector) recorded a solar energetic particle event superimposed with distinctive spikes in its counts. The spikes appeared as Dawn crossed into the southern hemisphere on the dayside of the planet and reappeared twice at the same location on consecutive orbits after the solar event had ceased. The spike pattern was absent from the measurements of the Bismuth Germanate (BGO) scintillator. This suggests the radiation responsible for the bursts in the exterior phoswich scintillator and any of their by-products were fully absorbed by materials surrounding the BGO. The source particles causing the enhancements were likely swift electrons that penetrated directly into the phoswich or associated bremsstrahlung produced in surrounding materials. The phoswich detection threshold for electrons is 20 keV and energy deposition during spike events cut off at about 100 keV, providing an energy range for the electrons if the spikes are produced by bremsstrahlung. Electrons in planetary environments are known to reach such high energies via fast-Fermi acceleration at a bow shock. We investigate if the fast-Fermi acceleration process, which would imply a temporary bow shock at Ceres, can explain the energies and fluxes of the spikes detected by GRaND's +Z Phoswich scintillator.

  2. Bow shock and magnetosheath waves at Mercury

    NASA Technical Reports Server (NTRS)

    Fairfield, D. H.; Behannon, K. W.

    1975-01-01

    Mariner 10 measurements at the Mercury bow shock provide examples where the magnetic field is approximately parallel or perpendicular to the bow shock normal. Upstream of a broad irregular parallel shock, left hand circularly polarized waves are observed which cut off very sharply at approximately 4 Hz. Upstream of a perpendicular shock, right hand circularly polarized waves are observed which persist up to the Nyquist frequency of 12 Ha. Determination of the wave propagation vector as a function of frequency helps conclusively identify the waves as whistler mode waves propagating from the shock. The magnetosheath downstream of the parallel shock is disturbed more than that downstream of the perpendicular shock particularly below 1 Hz. In the latter case regular left hand polarized waves observed slightly above the proton gyrofrequency are identified as ion cyclotron waves with wavelength approximately 300 km which are Doppler shifted up to their observed frequency.

  3. Bow shock formation in a complex plasma.

    PubMed

    Saitou, Y; Nakamura, Y; Kamimura, T; Ishihara, O

    2012-02-10

    A bow shock is observed in a two-dimensional supersonic flow of charged microparticles in a complex plasma. A thin conducting needle is used to make a potential barrier as an obstacle for the particle flow in the complex plasma. The flow is generated and the flow velocity is controlled by changing a tilt angle of the device under the gravitational force. A void, microparticle-free region, is formed around the potential barrier surrounding the obstacle. The flow is bent around the leading edge of the void and forms an arcuate structure when the flow is supersonic. The structure is characterized by the bow shock as confirmed by a polytropic hydrodynamic theory as well as numerical simulation. PMID:22401079

  4. Direct observation of the recovery of an antiferroelectric phase during polarization reversal of an induced ferroelectric phase

    NASA Astrophysics Data System (ADS)

    Guo, Hanzheng; Tan, Xiaoli

    2015-04-01

    Electric fields are generally known to favor the ferroelectric polar state over the antiferroelectric nonpolar state for their Coulomb interactions with dipoles in the crystal. In this paper, we directly image an electric-field-assisted ferroelectric-to-antiferroelectric phase transition during polarization reversal of the ferroelectric phase in polycrystalline P b0.99{N b0.02[(Zr0.57Sn0.43) 0.92T i0.08] 0.98}O3 . With the electric-field in situ transmission electron microscopy technique, such an unlikely phenomenon is verified to occur by both domain morphology change and electron-diffraction analysis. The slower kinetics of the phase transition, compared with ferroelectric polarization reversal, is suggested to contribute to this unusual behavior.

  5. Radiological assessment of the femoral bowing in Japanese population

    PubMed Central

    Abdelaal, Ahmed Hamed Kassem; Yamamoto, Norio; Hayashi, Katsuhiro; Takeuchi, Akihiko; Morsy, Ahmad Fawaz; Miwa, Shinji; Kajino, Yoshitomo; Rubio, Donnel A.; Tsuchiya, Hiroyuki

    2016-01-01

    Introduction: Differences in the magnitude of bowing between races are well-known characteristics of the femur. Asian races have an increased magnitude of femoral bowing but most of the orthopedic implants designed for the femur do not match this exaggerated bowing. We calculated the sagittal and coronal femoral bowing in the Japanese population at different levels of the femur and addressed its surgical significance. Material and methods: We calculated the sagittal and coronal bowing of 132 Japanese femora using CT scan of the femur. A mathematical calculation of the radius of curvature at proximal, middle, and distal regions of the femur was used to determine the degree of femoral bowing. Results: Mean sagittal bowing of the femur was 581, 188, and 161 mm for the proximal, middle, and distal thirds of the femur and mean lateral bowing was 528, 5092, and 876 mm, respectively. Mean sagittal and coronal bowing for the whole femur was 175 and 2640 mm, respectively. No correlation was found between age, gender, length of femur, and the degree of bowing. Conclusion: Our study reveals that femoral bowing in the Japanese population is 175 mm in the sagittal plane and 2640 mm in the coronal plane; these values are greater than the femoral bowing in other ethnic groups studied in the literature. This may result in varying degrees of mismatch between the western-manufactured femoral intramedullary implants and the Japanese femur. We recommend that orthopedic surgeons to accurately perform preoperative evaluation of the femoral bowing to avoid potential malalignment, rotation, and abnormal stresses between the femur and implant. PMID:27163091

  6. A survey for Hα pulsar bow shocks

    SciTech Connect

    Brownsberger, Sasha; Romani, Roger W. E-mail: sashab@stanford.edu

    2014-04-01

    We report on a survey for Hα bow shock emission around nearby γ-detected energetic pulsars. This survey adds three Balmer-dominated neutron star bow shocks to the six previously confirmed examples. In addition to the shock around Fermi pulsar PSR J1741–2054, we now report Hα structures around two additional γ-ray pulsars, PSR J2030+4415 and PSR J1509–5850. These are the first known examples of Hα nebulae with pre-ionization halos. With new measurements, we show that a simple analytic model can account for the angular size and flux of the bow shocks' apices. The latter, in particular, provides a new pulsar probe and indicates large moments of inertia and smaller distances than previously assumed in several cases. In particular, we show that the re-measured PSR J0437–4715 shock flux implies I = (1.7 ± 0.2) × 10{sup 45}/(f {sub HI}sin i) g cm{sup 2}. We also derive a distance d ≈ 0.72 kpc for the γ-ray only pulsar PSR J2030+4415 and revised distances for PSRs J1959+2048 (1.4 kpc) and J2555+6535 (∼1 kpc), smaller than the conventional DM-estimated values. Finally, we report upper limits for 94 additional LAT pulsars. An estimate of the survey sensitivity indicates that for a warm neutral medium filling factor φ{sub WNM} ∼ 0.3 there should be a total of approximately nine Hα bow shocks in our LAT-targeted survey; given that seven such objects are now known, a much larger φ{sub WNM} seems problematic.

  7. Sulfur-tolerant redox-reversible anode material for direct hydrocarbon solid oxide fuel cells.

    PubMed

    Yang, Chenghao; Yang, Zhibin; Jin, Chao; Xiao, Guoliang; Chen, Fanglin; Han, Minfang

    2012-03-15

    A novel composite anode material consisting of K(2) NiF(4) -type structured Pr(0.8) Sr(1.2) (Co,Fe)(0.8) Nb(0.2) O(4+δ) (K-PSCFN) matrix with homogenously dispersed nano-sized Co-Fe alloy (CFA) has been obtained by annealing perovskite Pr(0.4) Sr(0.6) Co(0.2) Fe(0.7) Nb(0.1) O(3-δ) (P-PSCFN) in H(2) at 900 °C. The K-PSCFN-CFA composite anode is redox-reversible and has demonstrated similar catalytic activity to Ni-based cermet anode, excellent sulfur tolerance, remarkable coking resistance and robust redox cyclability.

  8. Direct enantioselective separation of bevantolol by high-performance liquid chromatography on normal and reverse cellulose chiral stationary phases.

    PubMed

    Aboul-Enein, H Y; Serignese, V

    1994-01-01

    A direct, isocratic and simple chromatographic method is described for the enantiomeric separation of bevantolol (BEV) using normal and reverse cellulose tris (3,5-dimethylphenylcarbamate) chiral stationary phases (CSPs) known as Chiralcel OD and Chiralcel OD-R, respectively. The effect of various alcohols present in the mobile phase on the separation factor (a) and resolution factor (Rs) has been studied. The method has been used to determine and identify the BEV enantiomers in human urine after oral administration of racemic BEV. The chiral recognition mechanism(s) between the analyte and these chiral stationary phases is proposed.

  9. Direct imaging of the magnetic polarity and reversal mechanism in individual Fe(3-x)O4 nanoparticles.

    PubMed

    Moya, Carlos; Iglesias-Freire, Óscar; Pérez, Nicolás; Batlle, Xavier; Labarta, Amilcar; Asenjo, Agustina

    2015-05-01

    This work reports on the experimental characterization of the magnetic domain configurations in cubic, isolated Fe3-xO4 nanoparticles with a lateral size of 25-30 nm. The magnetic polarity at remanence of single domain ferrimagnetic Fe3-xO4 nanoparticles deposited onto a carbon-silicon wafer is observed by magnetic force microscopy. The orientations of these domains provide a direct observation of the magneto-crystalline easy axes in each individual nanoparticle. Furthermore, the change in the domain orientation with an external magnetic field gives evidence of particle magnetization reversal mediated by a coherent rotation process that is also theoretically predicted by micromagnetic calculations.

  10. Direct in situ nitridation of nanostructured metal oxide deposited semiconductor interfaces: tuning the response of reversibly interacting sensor sites.

    PubMed

    Laminack, William I; Gole, James L

    2014-08-25

    Metal-oxide nanostructure-decorated extrinsic semiconductor interfaces modified through in situ nitridation greatly expand the range of sensor interface response. Select metal-oxide sites, deposited to an n-type nanopore-coated microporous interface, direct a dominant electron-transduction process for reversible chemical sensing, which minimizes chemical-bond formation. The oxides are modified to decrease their Lewis acidity through a weak interaction to form metal oxynitride sites. Conductometric and X-ray photoelectron spectroscopy measurements demonstrate that in situ treatment changes the reversible interaction with the analytes NH3 and NO. The sensor range is extended, which creates a distinct new family of responses determined by the Lewis acidity/basicity of a given analyte relative to that of the nanostructures chosen to decorate the interface. The analyte response, broadened in a substantial and predictable way by nitridation, is explained by the recently developing inverse hard/soft acid/base model (IHSAB) of reversible electron transduction. PMID:24862834

  11. Population genetic structure and direct observations reveal sex-reversed patterns of dispersal in a cooperative bird

    PubMed Central

    Harrison, Xavier A; York, Jennifer E; Young, Andrew J

    2014-01-01

    Sex-biased dispersal is pervasive and has diverse evolutionary implications, but the fundamental drivers of dispersal sex biases remain unresolved. This is due in part to limited diversity within taxonomic groups in the direction of dispersal sex biases, which leaves hypothesis testing critically dependent upon identifying rare reversals of taxonomic norms. Here, we use a combination of observational and genetic data to demonstrate a rare reversal of the avian sex bias in dispersal in the cooperatively breeding white-browed sparrow weaver (Plocepasser mahali). Direct observations revealed that (i) natal philopatry was rare, with both sexes typically dispersing locally to breed, and (ii), unusually for birds, males bred at significantly greater distances from their natal group than females. Population genetic analyses confirmed these patterns, as (i) corrected Assignment index (AIc), FST tests and isolation-by-distance metrics were all indicative of longer dispersal distances among males than females, and (ii) spatial autocorrelation analysis indicated stronger within-group genetic structure among females than males. Examining the spatial scale of extra-group mating highlighted that the resulting ‘sperm dispersal’ could have acted in concert with individual dispersal to generate these genetic patterns, but gamete dispersal alone cannot account entirely for the sex differences in genetic structure observed. That leading hypotheses for the evolution of dispersal sex biases cannot readily account for these sex-reversed patterns of dispersal in white-browed sparrow weavers highlights the continued need for attention to alternative explanations for this enigmatic phenomenon. We highlight the potential importance of sex differences in the distances over which dispersal opportunities can be detected. PMID:25346189

  12. Contaminants of emerging concern in reverse osmosis brine concentrate from indirect/direct water reuse applications.

    PubMed

    Romeyn, Travis R; Harijanto, Wesley; Sandoval, Sofia; Delagah, Saied; Sharbatmaleki, Mohamadali

    2016-01-01

    Water shortage is becoming more common due to droughts and global population increases resulting in the increasing popularity of water reuse to create new water sources. Reverse osmosis (RO) membrane systems are popular in these applications since they can produce drinking water quality effluent. Unfortunately, RO systems have the drawback of generating concentrate streams that contain contaminants rejected by the membrane including chemicals of emerging concern (CECs). CECs are chemicals such as hormones, steroids, pesticides, pharmaceuticals, and personal care products that are used for their intended purpose and then released into wastewater. CECs are believed to be detrimental to aquatic wildlife health and pose an unknown human health risk. This research gathered the existing knowledge on CEC presence in concentrate, available proven concentrate treatment methods, their CEC removal abilities, and current CEC regulations. It was found that 127 CECs have been measured in RO concentrate with 100 being detected at least once. The most potent treatment process available is UV/H2O2 as it offers the highest removal rates for the widest range of chemicals. The less expensive process of ozone/biologically activated carbon offers slightly lower removal abilities. This comprehensive report will provide the groundwork for better understanding, regulating and treating concentrate stream CECs.

  13. Contaminants of emerging concern in reverse osmosis brine concentrate from indirect/direct water reuse applications.

    PubMed

    Romeyn, Travis R; Harijanto, Wesley; Sandoval, Sofia; Delagah, Saied; Sharbatmaleki, Mohamadali

    2016-01-01

    Water shortage is becoming more common due to droughts and global population increases resulting in the increasing popularity of water reuse to create new water sources. Reverse osmosis (RO) membrane systems are popular in these applications since they can produce drinking water quality effluent. Unfortunately, RO systems have the drawback of generating concentrate streams that contain contaminants rejected by the membrane including chemicals of emerging concern (CECs). CECs are chemicals such as hormones, steroids, pesticides, pharmaceuticals, and personal care products that are used for their intended purpose and then released into wastewater. CECs are believed to be detrimental to aquatic wildlife health and pose an unknown human health risk. This research gathered the existing knowledge on CEC presence in concentrate, available proven concentrate treatment methods, their CEC removal abilities, and current CEC regulations. It was found that 127 CECs have been measured in RO concentrate with 100 being detected at least once. The most potent treatment process available is UV/H2O2 as it offers the highest removal rates for the widest range of chemicals. The less expensive process of ozone/biologically activated carbon offers slightly lower removal abilities. This comprehensive report will provide the groundwork for better understanding, regulating and treating concentrate stream CECs. PMID:26819378

  14. Observed Foreshock Ions which are Actually Behind the Martian Bow Shock

    NASA Astrophysics Data System (ADS)

    Frahm, Rudy A.; Yamauchi, Masatoshi; Winningham, J. David; Lundin, Rickard; Sharber, James R.; Nilsson, Hans; Coates, Andrew J.; Mukherjee, Joey

    2016-04-01

    The Mars Express (MEx) Analyzer of Space Plasmas and Energetic Atoms (ASPERA-3) experiment contains ion and electron instruments for conducting plasma measurements. On January 23, 2012, during in-bound travel of MEx in the southern hemisphere of Mars traveling from its dawn side toward periapsis at dusk, the plasma instruments measured foreshock-like ion beams extending from outside the bow shock and into the magnetosphere, continuing to a distance of about a proton gyroradius from the bow shock. These ion beams were mostly protons, were observed to have energies greater than solar wind protons, and were not gyrating, in agreement with reflections of the solar wind proton beam. Furthermore, in the foreshock region, the ion energy gradually decreased toward the magnetosheath, in agreement with an acceleration by an outward-directed electric field in the bow shock. The observations also suggest that this electric field exists even inside the magnetosheath, within the distance of a proton gyroradius from the bow shock.

  15. CPR methodology with new steady-state criterion and more accurate statistical treatment of channel bow

    SciTech Connect

    Baumgartner, S.; Bieli, R.; Bergmann, U. C.

    2012-07-01

    An overview is given of existing CPR design criteria and the methods used in BWR reload analysis to evaluate the impact of channel bow on CPR margins. Potential weaknesses in today's methodologies are discussed. Westinghouse in collaboration with KKL and Axpo - operator and owner of the Leibstadt NPP - has developed an optimized CPR methodology based on a new criterion to protect against dryout during normal operation and with a more rigorous treatment of channel bow. The new steady-state criterion is expressed in terms of an upper limit of 0.01 for the dryout failure probability per year. This is considered a meaningful and appropriate criterion that can be directly related to the probabilistic criteria set-up for the analyses of Anticipated Operation Occurrences (AOOs) and accidents. In the Monte Carlo approach a statistical modeling of channel bow and an accurate evaluation of CPR response functions allow the associated CPR penalties to be included directly in the plant SLMCPR and OLMCPR in a best-estimate manner. In this way, the treatment of channel bow is equivalent to all other uncertainties affecting CPR. Emphasis is put on quantifying the statistical distribution of channel bow throughout the core using measurement data. The optimized CPR methodology has been implemented in the Westinghouse Monte Carlo code, McSLAP. The methodology improves the quality of dryout safety assessments by supplying more valuable information and better control of conservatisms in establishing operational limits for CPR. The methodology is demonstrated with application examples from the introduction at KKL. (authors)

  16. Curvature and bow of bulk GaN substrates

    NASA Astrophysics Data System (ADS)

    Foronda, Humberto M.; Romanov, Alexey E.; Young, Erin C.; Roberston, Christian A.; Beltz, Glenn E.; Speck, James S.

    2016-07-01

    We investigate the bow of free standing (0001) oriented hydride vapor phase epitaxy grown GaN substrates and demonstrate that their curvature is consistent with a compressive to tensile stress gradient (bottom to top) present in the substrates. The origin of the stress gradient and the curvature is attributed to the correlated inclination of edge threading dislocation (TD) lines away from the [0001] direction. A model is proposed and a relation is derived for bulk GaN substrate curvature dependence on the inclination angle and the density of TDs. The model is used to analyze the curvature for commercially available GaN substrates as determined by high resolution x-ray diffraction. The results show a close correlation between the experimentally determined parameters and those predicted from theoretical model.

  17. On the shape and motion of the Earth's bow shock

    NASA Astrophysics Data System (ADS)

    Meziane, K.; Alrefay, T. Y.; Hamza, A. M.

    2014-04-01

    Multipoint-measurements by the magnetic field Cluster-FGM (Flux Gate Magnetometer) are used to determine the local shock normal, and in turn allow the study of shock location shape and the velocity of the Earth's bow shock. The shock crossings cover orbits in which the spacecraft separation is of the order of ~600 km or less. A data selection of 133 bow shock crossings, ranging from quasi-steady perpendicular to moderately noisy oblique geometries, have been analyzed using a standard timing analysis. Prior to applying the timing technique, the magnetic field fluctuations, when present, are suppressed using low band-pass filtering. The present study contributes to similar studies conducted in the past and available in the literature through the inclusion of a larger data set. The shock standoff distance is determined conjointly with a paraboloid model and the results from a timing analysis. A statistical study reveals a standoff distance well in agreement with the standard gas dynamics model prediction for high Mach number MA. We have also found that for about half the crossings, the timing shock normals agree, within 11°, with a conic-based shock model. Our results strongly indicate that the motion of the shock is predominantly along the Sun-Earth direction; a departure from this direction is not related to the shock-crossing location. Shock velocities below ~80 km/s satisfactorily follow a nearly Gaussian distribution with zero mean and a standard deviation of ~42 km/s. Finally, we show that high speed motions are correlated with sharp increases in the solar wind upstream ram pressure, and are consistent with gas dynamics model predictions.

  18. Evolution of Bow-Tie Architectures in Biology

    PubMed Central

    Friedlander, Tamar; Mayo, Avraham E.; Tlusty, Tsvi; Alon, Uri

    2015-01-01

    Bow-tie or hourglass structure is a common architectural feature found in many biological systems. A bow-tie in a multi-layered structure occurs when intermediate layers have much fewer components than the input and output layers. Examples include metabolism where a handful of building blocks mediate between multiple input nutrients and multiple output biomass components, and signaling networks where information from numerous receptor types passes through a small set of signaling pathways to regulate multiple output genes. Little is known, however, about how bow-tie architectures evolve. Here, we address the evolution of bow-tie architectures using simulations of multi-layered systems evolving to fulfill a given input-output goal. We find that bow-ties spontaneously evolve when the information in the evolutionary goal can be compressed. Mathematically speaking, bow-ties evolve when the rank of the input-output matrix describing the evolutionary goal is deficient. The maximal compression possible (the rank of the goal) determines the size of the narrowest part of the network—that is the bow-tie. A further requirement is that a process is active to reduce the number of links in the network, such as product-rule mutations, otherwise a non-bow-tie solution is found in the evolutionary simulations. This offers a mechanism to understand a common architectural principle of biological systems, and a way to quantitate the effective rank of the goals under which they evolved. PMID:25798588

  19. 46 CFR 154.355 - Bow and stern loading piping.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Arrangements § 154.355 Bow and stern loading piping. (a) Bow and stern loading piping must: (1) Meet § 154.310; (2) Be installed in an area away from the accommodation, service, or control space on type IG hulls; (3) Be clearly marked; (4) Be segregated from the cargo piping by a removable spool piece in...

  20. Mach 5 bow shock control by a nanosecond pulse surface dielectric barrier discharge

    SciTech Connect

    Nishihara, M.; Takashima, K.; Rich, J. W.; Adamovich, I. V.

    2011-06-15

    Bow shock perturbations in a Mach 5 air flow, produced by low-temperature, nanosecond pulse, and surface dielectric barrier discharge (DBD), are detected by phase-locked schlieren imaging. A diffuse nanosecond pulse discharge is generated in a DBD plasma actuator on a surface of a cylinder model placed in air flow in a small scale blow-down supersonic wind tunnel. Discharge energy coupled to the actuator is 7.3-7.8 mJ/pulse. Plasma temperature inferred from nitrogen emission spectra is a few tens of degrees higher than flow stagnation temperature, T = 340 {+-} 30 K. Phase-locked Schlieren images are used to detect compression waves generated by individual nanosecond discharge pulses near the actuator surface. The compression wave propagates upstream toward the baseline bow shock standing in front of the cylinder model. Interaction of the compression wave and the bow shock causes its displacement in the upstream direction, increasing shock stand-off distance by up to 25%. The compression wave speed behind the bow shock and the perturbed bow shock velocity are inferred from the Schlieren images. The effect of compression waves generated by nanosecond discharge pulses on shock stand-off distance is demonstrated in a single-pulse regime (at pulse repetition rates of a few hundred Hz) and in a quasi-continuous mode (using a two-pulse sequence at a pulse repetition rate of 100 kHz). The results demonstrate feasibility of hypersonic flow control by low-temperature, repetitive nanosecond pulse discharges.

  1. [Posterior iris bowing after accommodation--elucidation of the etiology of pigment dispersion syndrome].

    PubMed

    Ueda, J; Sawaguchi, S; Watanabe, J; Shirakashi, M; Abe, H

    1997-02-01

    Recent advancements in imaging the anterior segment structures using the ultrasound biomicro scope (UBM) have proven the involvement of posterior iris bowing due to reverse pupillary block as the cause of pigment dispersion syndrome. In this report, we examined whether the posterior iris bowing occurs even in normal eyes following accommodation, and whether the degree of iris concavity tends to be greater in myopic eyes than in emmetropic eyes. The subjects were normal eyes with sufficient accommodation power, i.e. 5 myopic eyes with less than-5 diopter reflection, 5 emmetropic eyes within +/- 1 dioptor reflection, respectively. We obtained UBM images of the iris at 4 portions before and after accommodation, and measured the degree of posterior iris bowing. We found that almost all data shift posteriorly after accommodation, and that the iris concavity is more distinct in myopic eyes than in emmetropic eyes both before and after accommodation (before: p = 0.0004, after: p < 0.0001). From these results, we confirmed that iris concavity after accommodation occurs in normal eyes but not enough for iridozonular contact, and that pigment dispersion syndrome results from augmented iris concavity owing to pre-existing factors such as iris flexibility, myopia, and sufficient accommodation power. PMID:9124102

  2. The Influence of the Martian Bow Shock on Heavy Planetary Ions

    NASA Astrophysics Data System (ADS)

    Johnson, B. C.; Liemohn, M. W.; Stenberg, G.; Nilsson, H.; Ramstad, R.; Fraenz, M.

    2014-12-01

    Due to the extent of Mars' exosphere and the large gyroradii of some heavy planetary ions, it is expected that some atmospheric ions will encounter the bow shock. However, the effect that the bow shock has on these heavy ions is relatively unstudied. Mars Express (MEX) ion data is examined to determine whether significant differences exist in the velocity space distributions of energetic planetary ions inside and outside of the shock. To allow for determination of the solar wind motional electric field (Esw) using Mars Global Surveyor (MGS) magnetometer data, the study is focused on the time interval from early 2004 to late 2006 when MEX and MGS overlapped. For each 192 second measurement, an average velocity is assigned to heavy ions at high energies (> 2 keV). The possibility that there is turbulence in the magnetosheath altering the paths of heavy pickup ions will be tested by comparing flight directions relative to the direction of Esw in the magnetosheath to flight directions relative to the Esw direction upstream of the bow shock.

  3. Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis.

    PubMed

    Zeng, Qi-Kai; Du, Hong-Li; Wang, Jing-Fang; Wei, Dong-Qing; Wang, Xiao-Ning; Li, Yi-Xue; Lin, Ying

    2009-07-01

    A major problem when xylose is used for ethanol production is the intercellular redox imbalance arising from different coenzyme specificities of xylose reductase (XR) and xylitol dehydrogenase. The residue Lys21 in XR from Pichia stipitis was subjected to site-directed mutagenesis to alter its coenzyme specificity. The N272D mutant exhibited improved catalytic efficiency when NADH was the coenzyme. Both K21A and K21A/N272D preferred NADH to NADPH, their catalytic efficiencies for NADPH were almost zero. The catalytic efficiency of K21A/N272D for NADH was almost 9-fold and 2-fold that of K21A and the wild-type enzyme, respectively. Complete reversal of coenzyme specificity toward NADH and improved catalytic efficiency were achieved.

  4. Study of the relation between Pc 3 micropulsations and magnetosheath fluctuations and of the multisatellite, multimeasurement investigation of the earth's bow shock

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The structure and direction of bow shock waves and the occurence of Pc 3, 4 micropulsations were investigated. An observational description is given of a quasi-parallel structure in a plasma parameter regime. The use of approximation to estimate the thickness of thin, nearly perpendicular bow shocks at supralaminar Mach numbers is discussed. The pattern of energies of backstreaming protons in the foreshock are predicted.

  5. Controlled metal-semiconductor sintering/alloying by one-directional reverse illumination

    DOEpatents

    Sopori, Bhushan L.

    1993-01-01

    Metal strips deposited on a top surface of a semiconductor substrate are sintered at one temperature simultaneously with alloying a metal layer on the bottom surface at a second, higher temperature. This simultaneous sintering of metal strips and alloying a metal layer on opposite surfaces of the substrate at different temperatures is accomplished by directing infrared radiation through the top surface to the interface of the bottom surface with the metal layer where the radiation is absorbed to create a primary hot zone with a temperature high enough to melt and alloy the metal layer with the bottom surface of the substrate. Secondary heat effects, including heat conducted through the substrate from the primary hot zone and heat created by infrared radiation reflected from the metal layer to the metal strips, as well as heat created from some primary absorption by the metal strips, combine to create secondary hot zones at the interfaces of the metal strips with the top surface of the substrate. These secondary hot zones are not as hot as the primary hot zone, but they are hot enough to sinter the metal strips to the substrate.

  6. Direct observation of solid-state reversed transformation from crystals to quasicrystals in a Mg alloy

    PubMed Central

    Liu, Jian-Fang; Yang, Zhi-Qing; Ye, Heng-Qiang

    2015-01-01

    Phase transformation of quasicrystals is of interest in various fields of science and technology. Interestingly, we directly observed unexpected solid-state epitaxial nucleation and growth of Zn 6 Mg 3 Y icosahedral quasicrystals in a Mg alloy at about 573 K which is about 300 K below the melting point of Zn 6 Mg 3 Y, in contrast to formation of quasicrystals through solidification that was usually found in many alloys. Maximizing local packing density of atoms associated with segregation of Y and Zn in Mg adjacent to Mg/Zn 3 MgY interfaces triggered atomic rearrangement in Mg to form icosahedra coupled epitaxially with surface distorted icosahedra of Zn 3 MgY, which plays a critical role in the nucleation of icosahedral clusters. A local Zn:Mg:Y ratio close to 6:3:1, corresponding to a valence electron concentration of about 2.15, should have been reached to trigger the formation of quasicrystals at Mg/Zn 3 MgY interfaces. The solid-state icosahedral ordering in crystals opens a new window for growing quasicrystals and understanding their atomic origin mechanisms. Epitaxial growth of quasicrystals onto crystals can modify the surface/interface structures and properties of crystalline materials. PMID:26066096

  7. Direct observation of solid-state reversed transformation from crystals to quasicrystals in a Mg alloy.

    PubMed

    Liu, Jian-Fang; Yang, Zhi-Qing; Ye, Heng-Qiang

    2015-06-12

    Phase transformation of quasicrystals is of interest in various fields of science and technology. Interestingly, we directly observed unexpected solid-state epitaxial nucleation and growth of Zn6Mg3Y icosahedral quasicrystals in a Mg alloy at about 573 K which is about 300 K below the melting point of Zn6Mg3Y, in contrast to formation of quasicrystals through solidification that was usually found in many alloys. Maximizing local packing density of atoms associated with segregation of Y and Zn in Mg adjacent to Mg/Zn3MgY interfaces triggered atomic rearrangement in Mg to form icosahedra coupled epitaxially with surface distorted icosahedra of Zn3MgY, which plays a critical role in the nucleation of icosahedral clusters. A local Zn:Mg:Y ratio close to 6:3:1, corresponding to a valence electron concentration of about 2.15, should have been reached to trigger the formation of quasicrystals at Mg/Zn3MgY interfaces. The solid-state icosahedral ordering in crystals opens a new window for growing quasicrystals and understanding their atomic origin mechanisms. Epitaxial growth of quasicrystals onto crystals can modify the surface/interface structures and properties of crystalline materials.

  8. A biodifferential system of face-bow mechanics.

    PubMed

    Dougherty, H L; Beazley, W W

    1976-11-01

    A review of the literature, both scientific and commercial, did not demonstrate the separation of the inner and outer bows into a biodifferential interchangeable system. The prime design idea, to separate the inner and outer bows, increased versatility and yielded a multiple appliance with a greater range of use and safety. The joint couple systems could be adapted to fulfill the criteria cited in the literature during preliminary treatment (deciduous dentition), partial treatment, full-banded treatment, and retention. The biodifferential design was compatible with most mechanical orthodontic appliances and systems currently used. The three joint designs presented and the three inner bow lock devices fulfilled the parameters expected from the normal use of the present face-bow in necessary strength, stability, and use. Further, the use of a joint couple between the inner and outer bows expanded the versatility of the face-bow into a biodifferential system and allowed for an easily manageable and orderly change of forces, vectors, sizes, and shapes requiring little chair time and minimum instruction to the patient. The inner bow could be used as an intraoral appliance for bumpers, shields, and oral screens. These easily made, preformed, interlocking parts could be marked or color coded as to type and size and keyed, grooved, and designed to prevent inverted interlocking of parts. The inner bow could be tied in, as an aid in patient cooperation, or the inner and outer bows could be pinned or ligated together to prevent separation. One of the most important factors of the biodifferential system is protection of the patient from severe trauma to the eyes, face, and mouth due to misuse or accident, as has occurred in the one-piece face-bow. The biodifferential system fulfills the five criteria of the investigation: (1) a system of interchangeable, interlocking joint parts, (2) safety and dependability, (3) easy changes in force, vectors, and moments, (4) enhanced

  9. 3D hybrid simulations of the interaction of a magnetic cloud with a bow shock

    NASA Astrophysics Data System (ADS)

    Turc, L.; Fontaine, D.; Savoini, P.; Modolo, R.

    2015-08-01

    In this paper, we investigate the interaction of a magnetic cloud (MC) with a planetary bow shock using hybrid simulations. It is the first time to our knowledge that this interaction is studied using kinetic simulations which include self-consistently both the ion foreshock and the shock wave dynamics. We show that when the shock is in a quasi-perpendicular configuration, the MC's magnetic structure in the magnetosheath remains similar to that in the solar wind, whereas it is strongly altered downstream of a quasi-parallel shock. The latter can result in a reversal of the magnetic field north-south component in some parts of the magnetosheath. We also investigate how the MC affects in turn the outer parts of the planetary environment, i.e., from the foreshock to the magnetopause. We find the following: (i) The decrease of the Alfvén Mach number at the MC's arrival causes an attenuation of the foreshock region because of the weakening of the bow shock. (ii) The foreshock moves along the bow shock's surface, following the rotation of the MC's magnetic field. (iii) Owing to the low plasma beta, asymmetric flows arise inside the magnetosheath, due to the magnetic tension force which accelerates the particles in some parts of the magnetosheath and slows them down in others. (iv) The quasi-parallel region forms a depression in the shock's surface. Other deformations of the magnetopause and the bow shock are also highlighted. All these effects can contribute to significantly modify the solar wind/magnetosphere coupling during MC events.

  10. Nucleotide-Dependent Shape Changes in the Reverse Direction Motor, Myosin VI

    PubMed Central

    Song, Chun Feng; Sader, Kasim; White, Howard; Kendrick-Jones, John; Trinick, John

    2010-01-01

    We have studied the shape of myosin VI, the actin minus-end directed motor, by negative stain and metal shadow electron microscopy. Single particle processing was used to make two-dimensional averages of the stain images, which greatly increases the clarity and allows detailed comparisons with crystal structures. A total of 169,964 particle images were obtained from two different constructs in six different states (four nucleotide states and with and without Ca2+). The shape of truncated apo myosin VI was very similar to the apo crystal structure, with the lever arm bent strongly backward and around the motor domain. In the full-length molecule, the C-terminal part of the tail has an additional bend taking it back across the motor domain, which may reflect a regulated state. Addition of ATP, ADP, or ATP-γS resulted in a large change, straightening the molecule from the bent shape and swinging the lever by ∼140°. Although these nucleotides would not be expected to produce the pre-powerstroke state, myosin VI in their presence was most similar to the truncated crystal structure with bound ADP-VO4, which is thought to show the pre-powerstroke shape. The nucleotide data were therefore substantially different from expectation based on crystal structures. The full-length molecule was almost completely monomeric; only ∼1% were dimers, joined through the ends of the tail. Addition of calcium ions appeared to result in release of the second calmodulin light chain. In negatively stained molecules there was little indication of extended α-helical structure in the tail, but molecules viewed by metal shadowing had a tail ∼3× longer, 29 vs. 9 nm, part of which is likely to be a single α-helix. PMID:21081082

  11. Observation of Motion of Bowed Strings and Resonant Strings in Violin Performances

    NASA Astrophysics Data System (ADS)

    Matsutani, Akihiro

    2013-10-01

    The motion of a bowed string and a resonant string of a violin were simultaneously observed for the first time. The results of the direct observation of string motion in double stops and harmonics are also presented. The importance of the resonance was experimentally demonstrated from these observations. It is suggested that players should take account of the resonance and ideal Helmholtz motion in violin performances.

  12. A computational exploration of the differences between prompt and bow shock initiation of explosives by shaped charge jets

    NASA Astrophysics Data System (ADS)

    Mellor, Christopher; James, Hugh R.; Goff, Michael J.

    2012-03-01

    The use of the CREST reactive burn model in conjunction with results from the open literature demonstrates the differences between prompt and bow shock initiation where the diameter of the shaped charge jet is much larger than the failure diameter of the explosive. The type of cover plate protecting the explosive can play an important role in determining the bow shock structure. For most scenarios of interest the burn model shows the need for the bow shock to build in strength before reaching an amplitude where significant reaction is triggered, and hence explains the observed very long runs to detonation that are often required by this mechanism. While the compression of the explosive between the bow shock and the jet provides much greater pressures than those seen in the bow shock, the relative thermodynamic inefficiency of the compression process means that this region contributes little to the direct generation of reaction. In contrast prompt shocks exhibit complete explosive burn at an early stage and the occasional long run distance is due to delays in this reaction achieving a diverging detonation.

  13. Offset semi-parabolic nanoantenna made of a photonic crystal parabolic mirror and a plasmonic bow-tie antenna.

    PubMed

    Hattori, Haroldo T

    2014-10-10

    In a parabolic mirror, light coming parallel to the antenna passes through its focal point. In this work, a waveguide feeds a semi-parabolic photonic crystal mirror and the emerging beam feeds a bow-tie antenna placed at the mirror's focal point-it is shown that the antenna system can not only feed a bow-tie antenna (producing a localized moderately high electric field) but also produces a directional radiation beam. The semi-parabolic mirror is also modified to reduce reflection back to the feeding waveguide.

  14. Direct observation of λ-DNA molecule reversal movement within microfluidic channels under electric field with single molecule imaging technique

    NASA Astrophysics Data System (ADS)

    Fengyun, Yang; Kaige, Wang; Dan, Sun; Wei, Zhao; Hai-qing, Wang; Xin, He; Gui-ren, Wang; Jin-tao, Bai

    2016-07-01

    The electrodynamic characteristics of single DNA molecules moving within micro-/nano-fluidic channels are important in the design of biomedical chips and bimolecular sensors. In this study, the dynamic properties of λ-DNA molecules transferring along the microchannels driven by the external electrickinetic force were systemically investigated with the single molecule fluorescence imaging technique. The experimental results indicated that the velocity of DNA molecules was strictly dependent on the value of the applied electric field and the diameter of the channel. The larger the external electric field, the larger the velocity, and the more significant deformation of DNA molecules. More meaningfully, it was found that the moving directions of DNA molecules had two completely different directions: (i) along the direction of the external electric field, when the electric field intensity was smaller than a certain threshold value; (ii) opposite to the direction of the external electric field, when the electric field intensity was greater than the threshold electric field intensity. The reversal movement of DNA molecules was mainly determined by the competition between the electrophoresis force and the influence of electro-osmosis flow. These new findings will theoretically guide the practical application of fluidic channel sensors and lab-on-chips for precisely manipulating single DNA molecules. Project supported by the National Natural Science Foundation of China (Grant No. 61378083), the International Cooperation Foundation of the National Science and Technology Major Project of the Ministry of Science and Technology of China (Grant No. 2011DFA12220), the Major Research Plan of National Natural Science Foundation of China (Grant No. 91123030), and the Natural Science Foundation of Shaanxi Province of China (Grant Nos. 2010JS110 and 2013SZS03-Z01).

  15. Direct observation of λ-DNA molecule reversal movement within microfluidic channels under electric field with single molecule imaging technique

    NASA Astrophysics Data System (ADS)

    Fengyun, Yang; Kaige, Wang; Dan, Sun; Wei, Zhao; Hai-qing, Wang; Xin, He; Gui-ren, Wang; Jin-tao, Bai

    2016-07-01

    The electrodynamic characteristics of single DNA molecules moving within micro-/nano-fluidic channels are important in the design of biomedical chips and bimolecular sensors. In this study, the dynamic properties of λ-DNA molecules transferring along the microchannels driven by the external electrickinetic force were systemically investigated with the single molecule fluorescence imaging technique. The experimental results indicated that the velocity of DNA molecules was strictly dependent on the value of the applied electric field and the diameter of the channel. The larger the external electric field, the larger the velocity, and the more significant deformation of DNA molecules. More meaningfully, it was found that the moving directions of DNA molecules had two completely different directions: (i) along the direction of the external electric field, when the electric field intensity was smaller than a certain threshold value; (ii) opposite to the direction of the external electric field, when the electric field intensity was greater than the threshold electric field intensity. The reversal movement of DNA molecules was mainly determined by the competition between the electrophoresis force and the influence of electro-osmosis flow. These new findings will theoretically guide the practical application of fluidic channel sensors and lab-on-chips for precisely manipulating single DNA molecules. Project supported by the National Natural Science Foundation of China (Grant No. 61378083), the International Cooperation Foundation of the National Science and Technology Major Project of the Ministry of Science and Technology of China (Grant No. 2011DFA12220), the Major Research Plan of National Natural Science Foundation of China (Grant No. 91123030), and the Natural Science Foundation of Shaanxi Province of China (Grant Nos. 2010JS110 and 2013SZS03-Z01).

  16. Face bow and articulator for planning orthognathic surgery: 1 face bow.

    PubMed

    Walker, Fraser; Ayoub, Ashraf F; Moos, Khursheed F; Barbenel, Joseph

    2008-10-01

    Orthognathic surgery that involves movement of the maxilla relative to the skull is usually planned using casts mounted on an articulator. Accurate positioning of the maxilla relative to the skull is essential for reliable planning, but current methods of mounting casts on articulators are inaccurate and unreliable. We propose that the casts should be mounted using the relation between the horizontal plane and the resting head position to define the position of the skull. A photographic study of 10 subjects confirmed the reproducibility of the head position and its relation to the horizontal plane. A face bow incorporating a circular spirit level was used to transfer the relation between the horizontal and the maxillary dentition to a semiadjustable articulator. The angle between the horizontal and maxillary occlusal planes was measured from six lateral cephalograms and compared with those of casts mounted on a semiadjustable articulator using a face bow with either an orbital pointer or a spirit level. The face bow with a spirit level produced considerably more accurate results.

  17. Optimization of bow shape for a non ballast water ship

    NASA Astrophysics Data System (ADS)

    Van He, Ngo; Ikeda, Yoshiho

    2013-09-01

    In this research, a commercial CFD code "Fluent" was applied to optimization of bulbous bow shape for a non ballast water ships (NBS). The ship was developed at the Laboratory of the authors in Osaka Prefecture University, Japan. At first, accuracy of the CFD code was validated by comparing the CFD results with experimental results at towing tank of Osaka Prefecture University. In the optimizing process, the resistances acting on ships in calm water and in regular head waves were defined as the object function. Following features of bulbous bow shapes were considered as design parameters: volume of bulbous bow, height of its volume center, angle of bow bottom, and length of bulbous bow. When referring to the computed results given by the CFD like resistance, pressure and wave pattern made by ships in calm water and in waves, an optimal bow shape for ships was discovered by comparing the results in the series of bow shapes. In the computation on waves, the ship is in fully captured condition because shorter waves, λ/ L pp <0.6, are assumed.

  18. Suprathermal Electrons at Saturn's Bow Shock

    NASA Astrophysics Data System (ADS)

    Masters, A.; Sulaiman, A. H.; Sergis, N.; Stawarz, L.; Fujimoto, M.; Coates, A. J.; Dougherty, M. K.

    2016-07-01

    The leading explanation for the origin of galactic cosmic rays is particle acceleration at the shocks surrounding young supernova remnants (SNRs), although crucial aspects of the acceleration process are unclear. The similar collisionless plasma shocks frequently encountered by spacecraft in the solar wind are generally far weaker (lower Mach number) than these SNR shocks. However, the Cassini spacecraft has shown that the shock standing in the solar wind sunward of Saturn (Saturn's bow shock) can occasionally reach this high-Mach number astrophysical regime. In this regime Cassini has provided the first in situ evidence for electron acceleration under quasi-parallel upstream magnetic conditions. Here we present the full picture of suprathermal electrons at Saturn's bow shock revealed by Cassini. The downstream thermal electron distribution is resolved in all data taken by the low-energy electron detector (CAPS-ELS, <28 keV) during shock crossings, but the higher energy channels were at (or close to) background. The high-energy electron detector (MIMI-LEMMS, >18 keV) measured a suprathermal electron signature at 31 of 508 crossings, where typically only the lowest energy channels (<100 keV) were above background. We show that these results are consistent with the theory in which the “injection” of thermal electrons into an acceleration process involves interaction with whistler waves at the shock front, and becomes possible for all upstream magnetic field orientations at high Mach numbers like those of the strong shocks around young SNRs. A future dedicated study will analyze the rare crossings with evidence for relativistic electrons (up to ˜1 MeV).

  19. The bow and arrow in northern North America.

    PubMed

    Maschner, Herbert; Mason, Owen K

    2013-01-01

    There were at least four waves of bow and arrow use in northern North America. These occurred at 12000, 4500, 2400, and after about 1300 years ago. But to understand the role of the bow and arrow in the north, one must begin in the eighteenth century, when the Russians first arrived in the Aleutian Islands. At that time, the Aleut were using both the atlatl and dart and the bow and arrow (Fig. ). This is significant for two particular and important reasons. First, there are few historic cases in which both technologies were used concurrently; second, the bow and arrow in the Aleutian Islands were used almost exclusively in warfare. The atlatl was a critical technology because the bow and arrow are useless for hunting sea mammals. One cannot launch an arrow from a kayak because it is too unstable and requires that both hands remain on a paddle. To use an atlatl, it is necessary only to stabilize the kayak with a paddle on one side and launch the atlatl dart with the opposite hand. The Aleut on the Alaska Peninsula did indeed use the bow and arrow to hunt caribou there. However, in the 1,400 km of the Aleutian Islands, there are no terrestrial mammals except humans and the bow was reserved almost exclusively for conflicts among them. The most significant event in the history of the bow and arrow is not its early introduction, but rather the Asian War Complex 1300 years ago, when the recurve and backed bows first entered the region, altering regional and hemispheric political dynamics forever. [Figure: see text].

  20. Reverse Kirner's deformity: case report.

    PubMed

    Lau, Yeong J; Tonkin, Michael A

    2009-03-01

    Kirner's deformity is a rare congenital deformity, usually of the little finger, with volar and radial bowing of the distal phalanx. The etiology of this deformity is unclear. We describe a case of a 9-year-old girl with radiographic changes classic for Kirner's deformity but with the curvature and nail changes in the dorsal direction.

  1. Structural changes in cuticles on violin bow hair caused by wear.

    PubMed

    Yamamoto, Tomoko; Sugiyama, Shigeru

    2010-01-01

    A bow with horse tail hair is used to play the violin. New and worn-out bow hairs were observed by atomic force microscopy. The cuticles of the new bow hair were already damaged by bleach and delipidation, however the worn-out bow hairs were much more damaged and broken off by force, which relates to wearing out. PMID:20139598

  2. Structural changes in cuticles on violin bow hair caused by wear.

    PubMed

    Yamamoto, Tomoko; Sugiyama, Shigeru

    2010-01-01

    A bow with horse tail hair is used to play the violin. New and worn-out bow hairs were observed by atomic force microscopy. The cuticles of the new bow hair were already damaged by bleach and delipidation, however the worn-out bow hairs were much more damaged and broken off by force, which relates to wearing out.

  3. Ion distributions in the Earth's foreshock upstream from the bow shock

    NASA Technical Reports Server (NTRS)

    Fuselier, S. A.

    1995-01-01

    A variety of suprathermal and energetic ion distributions are found upstream from shocks. Some distributions, such as field-aligned beams, are generated directly at the shock either through reflection processes or through leakage from the hotter downstream region. Other distributions, such as intermediate distributions, evolve from these parent distributions through wave-particle interactions. This paper reviews our current understanding of the creation and evolution of suprathermal distributions at shocks. Examples of suprathermal ion distributions are taken from observations at the Earth's bow shock. Particular emphasis is placed on the creation of field-aligned beams and specularly reflected ion distributions and on the evolution of these distributions in the Earth's ion foreshock. However, the results from this heavily studied region are applicable to interplanetary shocks, bow shocks at other planets, and comets.

  4. On a remarkable similarity between the propagation of whistlers and the bow wave of a ship

    NASA Astrophysics Data System (ADS)

    Gurnett, Donald A.

    It is well known that lightning-generated whistlers propagate along the Earth's magnetic field lines within a cone that at low frequencies makes an angle of 19°28‧ with respect to the local magnetic field. This angle turns out to be exactly the same as the half-angle of the bow wave of a ship in deep water. Both problems are complicated by the fact that the wave propagation is dispersive. In this paper we show that these two seemingly unrelated problems can be understood using the same basic approach, which is to analyze the direction of the group velocity as a function of the wave normal angle. This approach may have applications to other problems of geophysical interest, such as the bow wave generated by the interaction of a large object with a moving plasma.

  5. Interplanetary magnetic field control of the Mars bow shock - Evidence for Venuslike interaction

    NASA Technical Reports Server (NTRS)

    Zhang, T. L.; Schwingenschuh, K.; Lichtenegger, H.; Riedler, W.; Russell, C. T.

    1991-01-01

    The Mars bow shock location and shape have been determined by examining the Phobos spacecraft magnetometer data. Observations show that the position of the terminator bow shock varies with interplanetary magnetic field orientation in the same way as at Venus. The shock is farthest from Mars in the direction of the interplanetary electric field, consistent with the idea that mass loading plays an important role in the solar wind interaction with Mars. The shock cross section at the terminator plane is asymmetric and is controlled by the interplanetary magnetic field. The shock is farther from Mars during solar maximum. Thus the solar wind interaction with Mars appears to be Venuslike, with a magnetic moment too small to affect significantly the solar wind interaction.

  6. MAVEN observations of gyrotropic electron distributions upstream of Mars bow shock

    NASA Astrophysics Data System (ADS)

    Meziane, Karim; McFadden, James; Hamza, A. M.; Mazelle, Christian; Jakosky, Bruce; Mitchell, David; Halekas, Jasper; Espley, Jared; Connerney, J. E. D.

    2016-07-01

    Recent observations upstream from the Martian bow shock by the MAVEN Solar Wind Electron Analyzer (SWEA) experiment are presented. Flux enhancements of electrons with energies 70-400 eV are always observed when MAVEN spacecraft is magnetically connected to the shock. A detailed examination of the pitch angle distribution shows that the enhanced fluxes are associated with electrons moving away from Mars. In the full 3-D angular distribution, the electrons appear in an 'annulus' centered along the IMF direction. Moreover, the gyrotropic character is observed over a large range of shock geometry from quasi-parallel to quasi-perpendicular. These signatures in the electron distribution function strongly suggest that the reflection off the shock is the main mechanism for the production of Martian foreshock electrons. A quantitative analysis of electron distributions is carried out in order to probe the characteristics of the Martian bow shock.

  7. Interplanetary magnetic field control of the Mars bow shock: Evidence for Venuslike interaction

    SciTech Connect

    Zhang, T.L.; Schwingenschuh, K.; Lichtenegger, H.; Riedler, W. ); Russell, C.T.; Luhmann, J.G. )

    1991-07-01

    The Mars bow shock location and shape have been determined by examining the PHOBOS spacecraft magnetometer data. Observations show that the position of the terminator bow shock varies with interplanetary magnetic field orientation in the same way as at Venus. The shock is farthest from Mars in the direction of the interplanetary electric field, consistent with the idea that mass loading plays an important role in the solar wind interaction with Mars. The authors also find that the shock cross section at the terminator plane is asymmetric and is controlled by the interplanetary magnetic field as expected from the asymmetric propagation velocity of the fast magnetosonic wave. Comparing with earlier mission data, they show that the Mars shock location varies with solar activity. The shock is farther from Mars during solar maximum. Thus the solar wind interaction with Mars appears to be Venuslike, with a magnetic moment too small to affect significantly the solar wind interaction.

  8. The propagation and growth of whistler mode waves generated by electron beams in earth's bow shock

    NASA Technical Reports Server (NTRS)

    Tokar, R. L.; Gurnett, D. A.

    1985-01-01

    In this study, the propagation and growth of whistler mode waves generated by electron beams within earth's bow shock is investigated using a planar model for the bow shock and a model electron distribution function. Within the shock, the model electron distribution function possesses a field-aligned T greater than T beam that is directed toward the magnetosheath. Waves with frequencies between about 1 and 100 Hz with a wide range of wave normal angles are generated by the beam via Landau and anomalous cyclotron resonances. However, because the growth rate is small and because the wave packets traverse the shock quickly, these waves do not attain large amplitudes. Waves with frequencies between about 30 and 150 Hz with a wide range of wave normal angles are generated by the beam via the normal cyclotron resonance. The ray paths for most of these waves are directed toward the solar wind although some wave packets, due to plasma convection travel transverse to the shock normal. These wave packets grow to large amplitudes because they spend a long time in the growth region. The results suggest that whistler mode noise within the shock should increase in amplitude with increasing upstream theta sub Bn. The study provides an explanation for the origin of much of the whistler mode turbulence observed at the bow shock.

  9. High-Energy-Density, Laboratory-Astrophysics Studies of Jets and Bow Shocks

    SciTech Connect

    Foster, J M; Wilde, B H; Rosen, P A; Perry, T S; Khokhlov, A M; Coker, R F; Frank, A; Keiter, P A; Blue, B E; Drake, R P; Knauer, J P; Williams, R R

    2005-01-24

    Large-scale directional outflows of supersonic plasma, also known as ''jets'', are ubiquitous phenomena in astrophysics [1]. The interaction of such jets with surrounding matter often results in spectacular bow shocks, and intense radiation from radio to gamma-ray wavelengths. The traditional approach to understanding such phenomena is through theoretical analysis and numerical simulations. However, such numerical simulations have limited resolution, often assume axial symmetry, do not include all relevant physical processes, and fail to scale correctly in Reynolds number and perhaps other key dimensionless parameters. Additionally, they are frequently not tested by comparison with laboratory experiments. Recent advances in high-energy-density physics using large inertial-confinement-fusion devices now allow controlled laboratory experiments on macroscopic volumes of plasma of direct relevance relevant to astrophysics [2]. In this Letter we report the first results of experiments designed to study the evolution of supersonic plasma jets and the bow shocks they drive into a surrounding medium. Our experiments reveal both regular and highly complex flow patterns in the bow shock, thus opening a new window--complementary to computer simulations--into understanding the nature of three-dimensional astrophysical jets.

  10. Laser vibrometry measurements of vibration and sound fields of a bowed violin

    NASA Astrophysics Data System (ADS)

    Gren, Per; Tatar, Kourosh; Granström, Jan; Molin, N.-E.; Jansson, Erik V.

    2006-04-01

    Laser vibrometry measurements on a bowed violin are performed. A rotating disc apparatus, acting as a violin bow, is developed. It produces a continuous, long, repeatable, multi-frequency sound from the instrument that imitates the real bow-string interaction for a 'very long bow'. What mainly differs is that the back and forward motion of the real bow is replaced by the rotating motion with constant velocity of the disc and constant bowing force (bowing pressure). This procedure is repeatable. It is long lasting and allows laser vibrometry techniques to be used, which measure forced vibrations by bowing at all excited frequencies simultaneously. A chain of interacting parts of the played violin is studied: the string, the bridge and the plates as well as the emitted sound field. A description of the mechanics and the sound production of the bowed violin is given, i.e. the production chain from the bowed string to the produced tone.

  11. Low-energy particles at the bow shock, magnetopause, and outer magnetosphere of Saturn

    SciTech Connect

    Maclennan, C.G.; Lanzerotti, L.J.; Krimigis, S.M.; Lepping, R.P.

    1983-11-01

    Low-energy electron (>22 keV) and protons (> or approx. =30 keV) measured by the Low-Energy Charged Particle Experiment (LECP) during the encounters of the two Voyager spacecraft with Saturn are described. The characteristics of the dayside bow shock, magnetopause, and outer magnetosphere are emphasized. Only one crossing of the Saturian bow shock was observed inbound during the Voyager 1 encounter, whereas five crossings of the bow shock were identified during the Voyager 2 approach to the planet. During several of these bow shock crossings, low energy protons were observed to be streaming from the direction of the dawnside of the magnetosphere. In the magnetosheath the protons were observed to be oriented primarily with pitch angles of approx.90/sup 0/. Prior to the inbound magnetopause crossings (as defined by the magnetometer experiment on Voyager), the low-energy protons and electrons were observed to increase in intensity. Further, during Voyager 2 encounter, an increase in the proton and electron fluxes accompanied a change in orientation of the magnetosheath magnetioc field from one with a vertical component opposite to the planetary field to one with a vertical component in the direction of the planetary field. Examination of the flux distributions of the protons suggests that the magnetopuase was moving inward with a lower limit speed of approx.10 km/s during the Voyager 2 approach to the planet. The observed average subsolar magnetopause position at the time of Voyager 2 encounter was 18.5 R/sub S/, whereas during the Voyager 1 encounter it was considerably more extended, at 23.5 R/sub S/.

  12. A dynamic study of the effect on the maxillofacial complex of the face bow: analysis by a three-dimensional finite element method.

    PubMed

    Jinushi, H; Suzuki, T; Naruse, T; Isshiki, Y

    1997-02-01

    In order to investigate the effects of a face bow on the maxillofacial complex, we applied an analysis by a finite element method. To create a skull model, we measured an adult skull sample, and constructed a left lateral model without a mandible with 11 bones of 11 types, 30 sutures, and 3 synchondroses. The numbers of elements and nodes in the model were 1,207 and 1,539, respectively. The numbers of elements in the face bows used were 16 for the short type and 22 for the long one, respectively. Both of them were directly connected to the first molar tooth. To establish the constraining conditions, a symmetrical condition at the center of the model was chosen, and the basal part of the occipital bone was completely fixed. Each 1 kg loading was applied in three directions: 30 degrees post-superior, 0 degree posterior, and 30 degrees post-inferior. The results from this face bow loading experiment showed that the direction of displacement and the stress distribution were significantly different among the kinds of the face bows and the loading directions. For the short type face bow, simple compression appeared due to the post-superior loading and bending deformation due to the posterior and post-inferior ones. For the long type face bow, some bending deformations appeared, including anterior-elongation and posterior compression due to the post-superior loading. Post-inferior bending due to posterior loading and post-inferior bending and inferior displacement due to the post-inferior loading also appeared. Thus it is feasible to dynamically control the maxillofacial complex form by changing the type of the face bow and the direction of the loading traction.

  13. VIEW SOUTH FROM WITHING THE FORWARD (BOW) SECTION Rosie ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW SOUTH FROM WITHING THE FORWARD (BOW) SECTION - Rosie the Riveter National Historical Park, Rosie the Riveter Memorial, Off Regatta at Melville Square in Marina Park, Richmond, Contra Costa County, CA

  14. VIEW EAST SHOWING THE WEST SIDE OF THE FORWARD (BOW) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW EAST SHOWING THE WEST SIDE OF THE FORWARD (BOW) SECTION - Rosie the Riveter National Historical Park, Rosie the Riveter Memorial, Off Regatta at Melville Square in Marina Park, Richmond, Contra Costa County, CA

  15. VIEW SOUTH SHOWING THE STRUCTURE REPRESENTING THE FORWARD (BOW) SECTION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW SOUTH SHOWING THE STRUCTURE REPRESENTING THE FORWARD (BOW) SECTION OF A LIBERTY SHIP - Rosie the Riveter National Historical Park, Rosie the Riveter Memorial, Off Regatta at Melville Square in Marina Park, Richmond, Contra Costa County, CA

  16. 15. PORT SIDE OF FLYBRIDGE WING, LOOKING TOWARDS BOW AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. PORT SIDE OF FLYBRIDGE WING, LOOKING TOWARDS BOW AT SHIP'S CONTROLS AND IN BACKGROUND IS COMPASS. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  17. 18. DECK ABOVE PILOT HOUSE, LOOKING TOWARDS BOW, SHOWING DETAIL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. DECK ABOVE PILOT HOUSE, LOOKING TOWARDS BOW, SHOWING DETAIL, OF MAST. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  18. 17. DECK ABOVE CO'S STATEROOM, LOOKING TOWARDS BOW AT DECK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. DECK ABOVE CO'S STATEROOM, LOOKING TOWARDS BOW AT DECK ABOVE PILOT HOUSE. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  19. Electron velocity distributions near the earth's bow shock

    NASA Technical Reports Server (NTRS)

    Feldman, W. C.; Anderson, R. C.; Bame, S. J.; Gary, S. P.; Gosling, J. T.; Mccomas, D. J.; Thomsen, M. F.; Paschmann, G.; Hoppe, M. M.

    1983-01-01

    New information is presented on the general characteristics of electron distribution functions upstream, within, and downstream of the earth's bow shock, thereby providing new insights into the instabilities in collisionless shocks. The results presented are from a survey of electron velocity distributions measured near the earth's bow shock between October 1977 and December 1978 using the Los Alamos/Garching plasma instrumentation aboard ISEE 2. A wide variety of distribution shapes is found within the different plasma regions in close proximity to the bow shock. It is found that these shapes can be classified into general types that are characteristic of three different plasma regions, namely the upstream region or electron foreshock, the shock proper where most of the heating occurs, and the downstream region or the magnetosheath. Evidence is provided that field-aligned, rather than cross-field, instabilities are the major source of electron dissipation in the earth's bow shock.

  20. 3. CAP; CONICAL CAP HAS BOWED RAFTERS MORTISED INTO A ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. CAP; CONICAL CAP HAS BOWED RAFTERS MORTISED INTO A BOSS; ALSO SEEN ARE THE BRAKE WHEEL, WINDSHAFT AND TOP BEARING OF THE UPRIGHT SHAFT - Hayground Windmill, Windmill Lane, East Hampton, Suffolk County, NY

  1. Geology and sediment accumulation rates at Carrie Bow Cay, Belize

    USGS Publications Warehouse

    Shinn, Eugene A.; Hudson, J. Harold; Halley, Robert B.; Lidz, Barbara H.; Robbin, Daniel M.; Macintyre, Ian G.; Ruetzler, Klaus; Macintyre, Ian G.

    1982-01-01

    Two other rotary cores were drilled landward of the reef crest. One was drilled on the reef flat to a depth of 8.8 m, and the other was drilled on the southwest tip of Carrie Bow Cay to a depth of 17.7 m. Both cores encountered essentially uncemented carbonate reef sands with some coral rubble. Of the four rotary cores, only the Carrie Bow Cay core encountered Pleistocene bedrock. Radiocarbon dating of a large head of Siderastrea siderea, growing on bedrock from the Carrie Bow Cay core at a depth of 15.04 m below sea level, gave an age of 6960±110 years. The leached calcitic coralline bedrock, at a depth of 15.7 m below sea level in the Carrie Bow Cay core, contained root marks, and iron staining indicative of subaerial exposure.

  2. 3. VIEW NORTHEAST OF PORT BOW OF JFK IN DRYDOCK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW NORTHEAST OF PORT BOW OF JFK IN DRYDOCK NO. 5; PAINTERS WORKING APPLYING ANTI-FOULING PAINT BELOW WATER LINE. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Dry Dock No. 5, League Island, Philadelphia, Philadelphia County, PA

  3. 3. VIEW, LOOKING EAST, SHOWING BOW END OF VESSEL 37, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW, LOOKING EAST, SHOWING BOW END OF VESSEL 37, STERN OF VESSEL 38 WITH COLLAPSING LIVING QUARTERS TO RIGHT Susan Kardas, photographer, November 1984 - Shooters Island, Ships Graveyard, Vessel No. 37, Newark Bay, Staten Island (subdivision), Richmond County, NY

  4. 4. View of bow from port side, forward, vessel is ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. View of bow from port side, forward, vessel is on marine railway. Hooper Strait Lighthouse beyond. - Two-Sail Bateau E. C. COLLIER, Chesapeake Bay Maritime Museum, Mills Street, Saint Michaels, Talbot County, MD

  5. 19. DETAIL VIEW OF SKIFF BOW WITH OAK STEM AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. DETAIL VIEW OF SKIFF BOW WITH OAK STEM AND FRAMES PLANKED IN CEDAR USING COPPER CLINCH NAILS. TRANSOM OF SECOND SKIFF CAN BE SEEN BACKGROUND. - Lowell's Boat Shop, 459 Main Street, Amesbury, Essex County, MA

  6. 6. VIEW OF BOW OF VESSEL FROM STARBOARD SIDE, SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF BOW OF VESSEL FROM STARBOARD SIDE, SHOWING DOCKING CREW PREPARING TO REMOVE FOREFOOT FROM VESSEL'S STEM IN ORDER TO DRAW VESSEL OFF LIFT DOCK - Bugeye "Louise Travers", Intersection of Routes 2 & 4, Solomons, Calvert County, MD

  7. 15. Detail, northeast facade, operator's bow window and tower, showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Detail, northeast facade, operator's bow window and tower, showing knee braces carried on stone ancons used to support eaves, view to northwest, 90mm lens. - Southern Pacific Depot, 559 El Camino Real, San Carlos, San Mateo County, CA

  8. Ultra-high resolution steady-state micro-thermometry using a bipolar direct current reversal technique

    NASA Astrophysics Data System (ADS)

    Wu, Jason Yingzhi; Wu, Wei; Pettes, Michael Thompson

    2016-09-01

    The suspended micro-thermometry measurement technique is one of the most prominent methods for probing the in-plane thermal conductance of low dimensional materials, where a suspended microdevice containing two built-in platinum resistors that serve as both heater and thermometer is used to measure the temperature and heat flow across a sample. The presence of temperature fluctuations in the sample chamber and background thermal conductance through the device, residual gases, and radiation are dominant sources of error when the sample thermal conductance is comparable to or smaller than the background thermal conductance, on the order of 300 pW/K at room temperature. In this work, we present a high resolution thermal conductance measurement scheme in which a bipolar direct current reversal technique is adopted to replace the lock-in technique. We have demonstrated temperature resolution of 1.0-2.6 mK and thermal conductance resolution of 1.7-26 pW/K over a temperature range of 30-375 K. The background thermal conductance of the suspended microdevice is determined accurately by our method and allows for straightforward isolation of this parasitic signal. This simple and high-throughput measurement technique yields an order of magnitude improvement in resolution over similarly configured lock-in amplifier techniques, allowing for more accurate investigation of fundamental phonon transport mechanisms in individual nanomaterials.

  9. Simultaneous direct identification of genital microorganisms in voided urine using multiplex PCR-based reverse line blot assays.

    PubMed

    McKechnie, Michelle L; Kong, Fanrong; Gilbert, Gwendolyn L

    2013-01-01

    Our aim was to develop and evaluate sensitive methods that would allow simultaneous direct identification of multiple potential pathogens in clinical specimens for diagnosis and epidemiological studies, using a multiplex PCR-based reverse line blot assay. We have previously developed assays suitable for detection of bacterial respiratory and systemic pathogens. In this chapter we describe, in detail, a method developed to identify 14 genital microorganisms, for use in epidemiological studies of genital infection or colonization, using first voided urine specimens. The 14 urogenital pathogens or putative pathogens studied were Trichomonas vaginalis, Streptococcus pneumoniae, Neisseria gonorrhoeae, N. meningitidis, Chlamydia trachomatis, Ureaplasma parvum, U. urealyticum, Mycoplasma hominis, M. genitalium, Gardnerella vaginalis, Haemophilus influenzae, herpes simplex virus 1 and 2, and adenovirus. Two species-specific primer pairs and probes were designed for each target. The method was validated using a reference strain or a well-characterized clinical isolate of each target organism. In a clinical study among men attending sexual health clinics in Sydney, we used the assay to compare rates of detection of the 14 organisms in men with urethritis with those in asymptomatic controls and found the method to be sensitive, specific, convenient, and relatively inexpensive.

  10. Contribution of direct actions of the oxime HI-6 in reversing soman-induced muscle weakness in the rat diaphragm.

    PubMed

    Adler, M; Maxwell, D M; Filbert, M G; Deshpande, S S

    1994-01-01

    The actions of the bispyridinium oxime HI-6 ([[[(4-aminocarbonyl)pyridino]-methoxy]methyl]-2- [(hydroxyimino)methyl]-pyridinium dichloride) were investigated in vitro on rat phrenic nerve-hemidiaphragm preparations. Isometric twitch and tetanic tensions were elicited at 37 degrees C with supramaximal nerve stimulation at frequencies of 20 and 50 Hz. To approximate normal respiration patterns, trials consisting of 30 successive 0.55 s trains were alternated with 1.25 s rest periods. Under control conditions, the above stimulation pattern generated tensions that were well maintained at both frequencies. In contrast, a marked depression of muscle tension was observed in diaphragms removed from rats administered 339 micrograms/kg soman (3 LD50) and tested in vitro. Addition of HI-6, 4 h after soman exposure, led to a nearly complete recovery of muscle tension at 20 Hz. At 50 Hz, muscle tensions still declined especially when trains were elicited at 1.25 and 3 s intervals. The recovery by HI-6 observed in this study appears to be mediated by mechanisms unrelated to acetylcholinesterase reactivation since no increase of enzymatic activity was detected and the effect was reversed by a brief washout in oxime-free physiological solution. The results suggest that the direct action of HI-6 may play a role in restoring soman-induced diaphragmatic failure but this effect would be significant primarily under low use conditions. PMID:8157086

  11. Simultaneous direct identification of genital microorganisms in voided urine using multiplex PCR-based reverse line blot assays.

    PubMed

    McKechnie, Michelle L; Kong, Fanrong; Gilbert, Gwendolyn L

    2013-01-01

    Our aim was to develop and evaluate sensitive methods that would allow simultaneous direct identification of multiple potential pathogens in clinical specimens for diagnosis and epidemiological studies, using a multiplex PCR-based reverse line blot assay. We have previously developed assays suitable for detection of bacterial respiratory and systemic pathogens. In this chapter we describe, in detail, a method developed to identify 14 genital microorganisms, for use in epidemiological studies of genital infection or colonization, using first voided urine specimens. The 14 urogenital pathogens or putative pathogens studied were Trichomonas vaginalis, Streptococcus pneumoniae, Neisseria gonorrhoeae, N. meningitidis, Chlamydia trachomatis, Ureaplasma parvum, U. urealyticum, Mycoplasma hominis, M. genitalium, Gardnerella vaginalis, Haemophilus influenzae, herpes simplex virus 1 and 2, and adenovirus. Two species-specific primer pairs and probes were designed for each target. The method was validated using a reference strain or a well-characterized clinical isolate of each target organism. In a clinical study among men attending sexual health clinics in Sydney, we used the assay to compare rates of detection of the 14 organisms in men with urethritis with those in asymptomatic controls and found the method to be sensitive, specific, convenient, and relatively inexpensive. PMID:23104293

  12. A new technique to characterize CT scanner bow-tie filter attenuation and applications in human cadaver dosimetry simulations

    SciTech Connect

    Li, Xinhua; Shi, Jim Q.; Zhang, Da; Singh, Sarabjeet; Padole, Atul; Otrakji, Alexi; Kalra, Mannudeep K.; Liu, Bob; Xu, X. George

    2015-11-15

    Purpose: To present a noninvasive technique for directly measuring the CT bow-tie filter attenuation with a linear array x-ray detector. Methods: A scintillator based x-ray detector of 384 pixels, 307 mm active length, and fast data acquisition (model X-Scan 0.8c4-307, Detection Technology, FI-91100 Ii, Finland) was used to simultaneously detect radiation levels across a scan field-of-view. The sampling time was as short as 0.24 ms. To measure the body bow-tie attenuation on a GE Lightspeed Pro 16 CT scanner, the x-ray tube was parked at the 12 o’clock position, and the detector was centered in the scan field at the isocenter height. Two radiation exposures were made with and without the bow-tie in the beam path. Each readout signal was corrected for the detector background offset and signal-level related nonlinear gain, and the ratio of the two exposures gave the bow-tie attenuation. The results were used in the GEANT4 based simulations of the point doses measured using six thimble chambers placed in a human cadaver with abdomen/pelvis CT scans at 100 or 120 kV, helical pitch at 1.375, constant or variable tube current, and distinct x-ray tube starting angles. Results: Absolute attenuation was measured with the body bow-tie scanned at 80–140 kV. For 24 doses measured in six organs of the cadaver, the median or maximum difference between the simulation results and the measurements on the CT scanner was 8.9% or 25.9%, respectively. Conclusions: The described method allows fast and accurate bow-tie filter characterization.

  13. 76. The Silver Bow County Courthouse, 19101912, at West Granite ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    76. The Silver Bow County Courthouse, 1910-1912, at West Granite and Montana Streets, was designed by Link and Haire. The building has a dressed sandstone foundation, brick walls, and sandstone trim, parapet and columns. It was used as a barracks for the State militia when the city was placed under martial law following the dynamiting of the Old Miners' Union Hall in September, 1914. - Butte Historic District, Bounded by Copper, Arizona, Mercury & Continental Streets, Butte, Silver Bow County, MT

  14. Thermo-plastic analysis of a bowed sodium pump shaft

    SciTech Connect

    Weiner, E.O.

    1989-03-01

    A hollow sodium pump shaft was found to have a residual bow sufficient to cause unacceptable vibrations. Investigations suggested that the bow was caused by a sodium overfill event while the pump was shut down and the shaft was not turning. A rising sodium level with natural convection effects could result in local heating of the shaft. Even though the shaft may be essentially free, a local one-sided thermal loading may cause thermal stresses and plastic stains sufficient to give a residual bow when the thermal load is removed. A series of elastic-plastic analyses were carried out to assess the likelihood of the proposed mechanism's causing the residual bow. A special purpose computer program modelled the shaft as a Bernoulli beam. Isotropic hardening was evaluated by successive approximation. For each case studied, a loading sequence was followed by an assumed elastic unloading step, and the thermal loading zone was assumed small compared to the shaft length. These simplifying assumptions allowed parameterization of several variables--yield stress, thermal loading magnitude, extent of the heated zone around the shaft circumference, temperature distribution around the circumference, and shaft unrestrained/restrained conditions. Although the magnitude of the residual bow is not centered with the solution using mean parameters of this study, it is possible that a one-sided combination of parameter values did exist and that such a condition caused the bow under the proposed mechanism. 4 refs., 12 figs.

  15. Understanding the Impact of Reverse Transfer Students on Community Colleges. New Directions for Community Colleges, Number 106.

    ERIC Educational Resources Information Center

    Townsend, Barbara K., Ed.

    1999-01-01

    This issue describes an enrollment pattern emerging in higher education--students who are matriculated at, or have graduated from, a four-year college who then transfer to a two-year school, a process labeled "reverse transfer." The following articles are included: (1) "What Do We Know about Reverse Transfer Students?" (Barbara K. Townsend and…

  16. 75 FR 40820 - City of Broken Bow, Oklahoma; Project No. 12470-001-Oklahoma Broken Bow Re-Regulation Dam...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... Managing Properties Included in or Eligible for Inclusion in the National Register of Historic Places July... included in, or eligible for inclusion in, the National Register of Historic Places at the Broken Bow...

  17. Magnetosheath filamentary structures formed by ion acceleration at the quasi-parallel bow shock

    NASA Astrophysics Data System (ADS)

    Omidi, N.; Sibeck, D.; Gutynska, O.; Trattner, K. J.

    2014-04-01

    Results from 2.5-D electromagnetic hybrid simulations show the formation of field-aligned, filamentary plasma structures in the magnetosheath. They begin at the quasi-parallel bow shock and extend far into the magnetosheath. These structures exhibit anticorrelated, spatial oscillations in plasma density and ion temperature. Closer to the bow shock, magnetic field variations associated with density and temperature oscillations may also be present. Magnetosheath filamentary structures (MFS) form primarily in the quasi-parallel sheath; however, they may extend to the quasi-perpendicular magnetosheath. They occur over a wide range of solar wind Alfvénic Mach numbers and interplanetary magnetic field directions. At lower Mach numbers with lower levels of magnetosheath turbulence, MFS remain highly coherent over large distances. At higher Mach numbers, magnetosheath turbulence decreases the level of coherence. Magnetosheath filamentary structures result from localized ion acceleration at the quasi-parallel bow shock and the injection of energetic ions into the magnetosheath. The localized nature of ion acceleration is tied to the generation of fast magnetosonic waves at and upstream of the quasi-parallel shock. The increased pressure in flux tubes containing the shock accelerated ions results in the depletion of the thermal plasma in these flux tubes and the enhancement of density in flux tubes void of energetic ions. This results in the observed anticorrelation between ion temperature and plasma density.

  18. Magnetosheath Filamentary Structures Formed by Ion Acceleration at the Quasi-Parallel Bow Shock

    NASA Technical Reports Server (NTRS)

    Omidi, N.; Sibeck, D.; Gutynska, O.; Trattner, K. J.

    2014-01-01

    Results from 2.5-D electromagnetic hybrid simulations show the formation of field-aligned, filamentary plasma structures in the magnetosheath. They begin at the quasi-parallel bow shock and extend far into the magnetosheath. These structures exhibit anticorrelated, spatial oscillations in plasma density and ion temperature. Closer to the bow shock, magnetic field variations associated with density and temperature oscillations may also be present. Magnetosheath filamentary structures (MFS) form primarily in the quasi-parallel sheath; however, they may extend to the quasi-perpendicular magnetosheath. They occur over a wide range of solar wind Alfvénic Mach numbers and interplanetary magnetic field directions. At lower Mach numbers with lower levels of magnetosheath turbulence, MFS remain highly coherent over large distances. At higher Mach numbers, magnetosheath turbulence decreases the level of coherence. Magnetosheath filamentary structures result from localized ion acceleration at the quasi-parallel bow shock and the injection of energetic ions into the magnetosheath. The localized nature of ion acceleration is tied to the generation of fast magnetosonic waves at and upstream of the quasi-parallel shock. The increased pressure in flux tubes containing the shock accelerated ions results in the depletion of the thermal plasma in these flux tubes and the enhancement of density in flux tubes void of energetic ions. This results in the observed anticorrelation between ion temperature and plasma density.

  19. Modeling of Earth's bow shock: Applications

    NASA Astrophysics Data System (ADS)

    Chapman, J. F.; Cairns, Iver H.

    2004-11-01

    Shock-crossing data obtained from spacecraft are used to test the shock location models derived by [2003]. Three sets of data are considered: (1) ISEE 1 for 24-25 September 1987, (2) Wind, Geotail, IMP 8, and Interball for the intervals 26-27 April and 10-13 May 1999, and (3) IMP 8, Geotail, Magion-4, and Cluster during the period 1973-2003 from the bow shock database (available at http://nssdc.gsfc.nasa.gov/ftphelper/bowshock.html). Derived from MHD simulations, the two shock models are for angles θIMF = 45° and 90° between the upstream magnetic field BIMF and solar wind velocity vsw. These models have azimuthal asymmetries, and they depend explicitly on the upstream Mach number MA and ram pressure Pram. We also test 's [1995] rotationally symmetric shock model. The new models perform better on average than the rotationally symmetric model, providing some evidence and support for the shock's shape being strongly dependent upon MA and θIMF. We also compare our analyses here with model/spacecraft comparisons performed by [2003a] and discuss the importance of filtering on the model predictions.

  20. Field-aligned ion beams upstream of the earth's bow shock Evidence for a magnetosheath source

    NASA Technical Reports Server (NTRS)

    Thomsen, M. F.; Gosling, J. T.; Bame, S. J.; Feldman, W. C.; Paschmann, G.; Sckopke, N.

    1983-01-01

    High time resolution ISEE-1 and -2 observations of upstream field-aligned ion beams at several crossings of the earth's bow shock indicate that some beams are due to high energy magnetosheath particles leaking through the shock into the upstream region. The distribution immediately downstream of these oblique shocks consists of a 'core' of directly transmitted, slightly heated ions, plus a crescent-shaped, high-velocity distribution, centered roughly on the magnetic field in the direction toward the upstream region, with a fairly well defined low velocity cutoff.

  1. Measurement of bow tie profiles in CT scanners using a real-time dosimeter

    SciTech Connect

    Whiting, Bruce R.; Evans, Joshua D.; Williamson, Jeffrey F.; Dohatcu, Andreea C.; Politte, David G.

    2014-10-15

    Purpose: Several areas of computed tomography (CT) research require knowledge about the intensity profile of the x-ray fan beam that is introduced by a bow tie filter. This information is considered proprietary by CT manufacturers, so noninvasive measurement methods are required. One method using real-time dosimeters has been proposed in the literature. A commercially available dosimeter was used to apply that method, and analysis techniques were developed to extract fan beam profiles from measurements. Methods: A real-time ion chamber was placed near the periphery of an empty CT gantry and the dose rate versus time waveform was recorded as the x-ray source rotated about the isocenter. In contrast to previously proposed analysis methods that assumed a pointlike detector, the finite-size ion chamber received varying amounts of coverage by the collimated x-ray beam during rotation, precluding a simple relationship between the source intensity as a function of fan beam angle and measured intensity. A two-parameter model for measurement intensity was developed that included both effective collimation width and source-to-detector distance, which then was iteratively solved to minimize the error between duplicate measurements at corresponding fan beam angles, allowing determination of the fan beam profile from measured dose-rate waveforms. Measurements were performed on five different scanner systems while varying parameters such as collimation, kVp, and bow tie filters. On one system, direct measurements of the bow tie profile were collected for comparison with the real-time dosimeter technique. Results: The data analysis method for a finite-size detector was found to produce a fan beam profile estimate with a relative error between duplicate measurement intensities of <5%. It was robust over a wide range of collimation widths (e.g., 1–40 mm), producing fan beam profiles that agreed with a relative error of 1%–5%. Comparison with a direct measurement technique on

  2. Large scale motions of Neptune's bow shock: Evidence for control of the shock position by the rotation phase of Neptune's magnetic field

    NASA Technical Reports Server (NTRS)

    Cairns, Iver H.; Smith, Charles W.; Kurth, William S.; Gurnett, Donald A.; Moses, Stewart L.

    1991-01-01

    The Voyager 2 spacecraft observed high levels of Langmuir waves before the inbound crossing of Neptune's bow shock, thereby signifying magnetic connection of the bow shock. The Langmuir waves occurred in multiple bursts throughout two distinct periods separated by an 85 minute absence of wave activity. The times of onsets, peaks, and disappearances of the waves were used together with the magnetic field directions and spacecraft position, to perform a 'remote-sensing' analysis of the shape and location of Neptune's bow shock prior to the inbound bow shock crossing. The bow shock is assumed to have a parabolidal shape with a nose location and flaring parameter determined independently for each wave event. The remote-sensing analysis give a shock position consistent with the time of the inbound shock crossing. The flaring parameter of the shock remains approximately constant throughout each period of wave activity but differs by a factor of 10 between the two periods. The absence of waves between two periods of wave activity coincides with a large rotation of the magnetic field and a large increase in the solar wind ram pressure' both these effects lead to magnetic disconnection of the spacecraft from shock. The planetwards motion of the shock's nose from 38.5 R(sub N) to 34.5 R(sub N) during the second time period occurred while the solar wind ram pressure remained constant to within 15 percent. This second period of planetwards motion of the shock is therefore strong evidence for Neptune's bow shock moving in response to the rotation of Neptune's oblique, tilted magnetic dipole. Normalizing the ram pressure, the remotely-sensed shock moves sunwards during the first wave period and planetwards in the second wave period. The maximum standoff distance occurs while the dipole axis is close to being perpendicular to the Sun-Neptune direction. The remote-sensing analysis provides strong evidence that the location of Neptune's bow shock is controlled by Neptune's rotation

  3. Glial fibrillary acidic protein promoters direct adenovirus early 1A gene and human telomerase reverse transcriptase promoters direct sodium iodide symporter expression for malignant glioma radioiodine therapy.

    PubMed

    Li, Wei; Tan, Jian; Wang, Peng; Li, Ning; Li, Chengxia

    2015-01-01

    Malignant glioma can be treated with radioiodine following transfection with human sodium iodide symporter (hNIS) gene. Ad-Tp-E1A-Gp-NIS is engineered with human telomerase reverse transcriptase (hTERT) and glial fibrillary acidic protein (GFAP) promoters to express early region 1A (E1A) and hNIS genes, which may be useful in targeted gene therapy. The Ad-Tp-E1A-Gp-NIS was constructed and purified using the E1A and hNIS genes regulated by the hTERT and GFAP promoters, respectively. Glioma cells were infected by Ad-Tp-E1A-Gp-NIS. Selective replication ability of Ad-Tp-E1A-Gp-NIS was then evaluated by plaque forming assay, transgene expression by Western blot, (125)I-iodide uptake and efflux, clonogenicity following (131)I-iodide treatment in the tumor cells, and radioiodine therapy using nude mouse model. The Ad-Tp-E1A-Gp-NIS could selectively replicate; the hNIS gene was successfully expressed under the GFAP promoter. Western blot analyses using E1A- and hNIS-specific antibodies revealed two bands of approximately 40 and 70 kDa. In addition, the cells showed about 93.4 and 107.1 times higher (125)I uptake in U251 and U87 cells than in the control cells, respectively. Clonogenic assay indicated that >90% of cells transfected with Ad-Tp-E1A-Gp-NIS were killed. The Ad-Tp-E1A-Gp-NIS-transfected and 2 mCi (131)I-injected U87 xenograft nude mice survived the longest among the three groups. Ad-Tp-E1A-Gp-NIS has a good ability of selective replication and strong antitumor selectivity. An effective therapy of (131)I was achieved activity in malignant glioma cells after induction of tumor-specific iodide uptake activity by GFAP promoter-directed hNIS gene expression in vitro and in vivo.

  4. On the origin of the energetic ion events measured upstream the Earth's bow shock by STEREO, Cluster and Geotail

    NASA Astrophysics Data System (ADS)

    Kronberg, Elena; Bucik, Radoslav; Haaland, Stein E.; Klecker, Berndt; Keika, Kunihiro; Desai, Mihir; Daly, Patrick; Yamauchi, M.; Gomez-Herrero, Raul; Lui, Anthony

    The observations of upstream events up to distance of 3800 RE from Earth's bow shock were reported during the declining phase of the solar cycle in 2007. These upstream events mainly occurred after corotating interaction region (CIR) passed the Earth's magnetosphere. We study the relation between the upstream events observed from about 70 to 1750 RE away from the Earth and observations in the vicinity of the terrestrial bow shock (up to 30 RE). For this purpose, simultaneous measurements of energetic ions from STEREO-A, STEREO-B (far upstream region), and from Cluster and Geotail (near the bow shock) are used. In almost all cases the energetic ions far upstream are associated with the upstream events near the bow shock. The latter often coincide with sunward directed electron bursts, increased AE index (¿200 nT), intermittent sunward ion flows and the presence of the O+ ions, all of which imply a magnetospheric origin. We investigate possible mechanisms of CIR -magnetosphere interactions triggering acceleration and / or release of energetic particles.

  5. Lateralization of horizontal semicircular canal canalolithiasis and cupulopathy using bow and lean test and head-roll test.

    PubMed

    Kim, Chang-Hee; Kim, Yong Gyu; Shin, Jung Eun; Yang, Young Soo; Im, Donghyuk

    2016-10-01

    Accurate lateralization is important to improve treatment outcomes in horizontal semicircular canal (HSCC) benign paroxysmal positional vertigo (BPPV). To determine the involved side in HSCC-BPPV, the intensity of nystagmus has been compared in a head-roll test (HRT) and the direction of nystagmus was evaluated in a bow and lean test (BLT). The aim of this study is to compare the results of a BLT with those of a HRT for lateralization of HSCC-canalolithiasis and cupulopathy (heavy cupula and light cupula), and evaluate treatment outcomes in patients with HSCC-canalolithiasis. We conducted retrospective case reviews in 66 patients with HSCC-canalolithiasis and 63 patients with HSCC-cupulopathy. The affected side was identified as the direction of bowing nystagmus on BLT in 55 % (36 of 66) of patients with canalolithiasis, which was concordant with the HRT result in 67 % (24 of 36) of cases (concordant group). Lateralization was determined by comparison of nystagmus intensity during HRT in 30 patients who did not show bowing or leaning nystagmus. The remission rate after the first treatment was 71 % (17 of 24) in the concordant group and 45 % (5 of 11) in the discordant group. Both bowing and leaning nystagmus were observed in all patients with cupulopathy, and the side of the null plane was identified as the affected side. In conclusion, bowing and/or leaning nystagmus were observed in only 55 % of patients with HSCC-canalolithiasis, and the first treatment based on the result of BLT alone was effective in only 45 % of the patients in whom the BLT and HRT were discordant, which may suggest that the usefulness of BLT in lateralizing the HSCC-canalolithiasis may be limited. PMID:26758464

  6. Lateralization of horizontal semicircular canal canalolithiasis and cupulopathy using bow and lean test and head-roll test.

    PubMed

    Kim, Chang-Hee; Kim, Yong Gyu; Shin, Jung Eun; Yang, Young Soo; Im, Donghyuk

    2016-10-01

    Accurate lateralization is important to improve treatment outcomes in horizontal semicircular canal (HSCC) benign paroxysmal positional vertigo (BPPV). To determine the involved side in HSCC-BPPV, the intensity of nystagmus has been compared in a head-roll test (HRT) and the direction of nystagmus was evaluated in a bow and lean test (BLT). The aim of this study is to compare the results of a BLT with those of a HRT for lateralization of HSCC-canalolithiasis and cupulopathy (heavy cupula and light cupula), and evaluate treatment outcomes in patients with HSCC-canalolithiasis. We conducted retrospective case reviews in 66 patients with HSCC-canalolithiasis and 63 patients with HSCC-cupulopathy. The affected side was identified as the direction of bowing nystagmus on BLT in 55 % (36 of 66) of patients with canalolithiasis, which was concordant with the HRT result in 67 % (24 of 36) of cases (concordant group). Lateralization was determined by comparison of nystagmus intensity during HRT in 30 patients who did not show bowing or leaning nystagmus. The remission rate after the first treatment was 71 % (17 of 24) in the concordant group and 45 % (5 of 11) in the discordant group. Both bowing and leaning nystagmus were observed in all patients with cupulopathy, and the side of the null plane was identified as the affected side. In conclusion, bowing and/or leaning nystagmus were observed in only 55 % of patients with HSCC-canalolithiasis, and the first treatment based on the result of BLT alone was effective in only 45 % of the patients in whom the BLT and HRT were discordant, which may suggest that the usefulness of BLT in lateralizing the HSCC-canalolithiasis may be limited.

  7. Numerical simulations of Mach stem formation via intersecting bow shocks

    NASA Astrophysics Data System (ADS)

    Hansen, E. C.; Frank, A.; Hartigan, P.; Yirak, K.

    2015-12-01

    Hubble Space Telescope observations show bright knots of Hα emission within outflowing young stellar jets. Velocity variations in the flow create secondary bow shocks that may intersect and lead to enhanced emission. When the bow shocks intersect at or above a certain critical angle, a planar shock called a Mach stem is formed. These shocks could produce brighter Hα emission since the incoming flow to the Mach stem is parallel to the shock normal. In this paper we report first results of a study using 2-D numerical simulations designed to explore Mach stem formation at the intersection of bow shocks formed by hypersonic "bullets" or "clumps". Our 2-D simulations show how the bow shock shapes and intersection angles change as the adiabatic index γ changes. We show that the formation or lack of a Mach stem in our simulations is consistent with the steady-state Mach stem formation theory. Our ultimate goal, which is part of an ongoing research effort, is to characterize the physical and observational consequences of bow shock intersections including the formation of Mach stems.

  8. Venus bow shocks at unusually large distances from the planet

    NASA Technical Reports Server (NTRS)

    Steinolfson, R. S.; Cable, S.

    1993-01-01

    Recent analysis of data from the Pioneer Venus Orbiter (PVO) has shown that the bow shock often travels to unusually large distances from the planet when the solar wind magnetosonic Mach number is near unity. We suggest that distant bow shocks can be explained as an integral part of the response of the global solar wind/Venus interaction to the anomalous local solar wind conditions that existed during the time of these observations. The lower-than-normal plasma beta and magnetosonic Mach number are in a parameter regime for which the usual fast-mode bow shock close to the planet may not provide the necessary compression and deflection of the solar wind. Using MHD simulations we show that, for these conditions, the usual fast shock is replaced by a bow shock consisting of an intermediate shock near the Sun-Venus line and a fast shock at large distances from the Sun-Venus line. This composite bow shock propagates upstream away from the planet at a low speed and appears to be approaching a new equilibrium stand-off location at a large distance from the planet.

  9. The existence and nature of the interstellar bow shock

    SciTech Connect

    Ben-Jaffel, Lotfi; Strumik, M.; Ratkiewicz, R.; Grygorczuk, J.

    2013-12-20

    We report a new diagnosis of two different states of the local interstellar medium (LISM) near our solar system by using a sensitivity study constrained by several distinct and complementary observations of the LISM, solar wind, and inner heliosphere. Assuming the Interstellar Boundary Explorer (IBEX) He flow parameters for the LISM, we obtain a strength of ∼2.7 ± 0.2 μG and a direction pointing away from galactic coordinates (28, 52) ± 3° for the interstellar magnetic field as a result of fitting Voyager 1 and Voyager 2 in situ plasma measurements and IBEX energetic neutral atoms ribbon. When using Ulysses parameters for the LISM He flow, we recently reported the same direction but with a strength of 2.2 ± 0.1 μG. First, we notice that with Ulysses He flow, our solution is in the expected hydrogen deflection plane (HDP). In contrast, for the IBEX He flow, the solution is ∼20° away from the corresponding HDP plane. Second, the long-term monitoring of the interplanetary H I flow speed shows a value of ∼26 km s{sup –1} measured upwind from the Doppler shift in the strong Lyα sky background emission line. All elements of the diagnosis seem therefore to support Ulysses He flow parameters for the interstellar state. In that frame, we argue that reliable discrimination between superfast, subfast, or superslow states of the interstellar flow should be based on most existing in situ and remote observations used together with global modeling of the heliosphere. For commonly accepted LISM ionization rates, we show that a fast interstellar bow shock should be standing off upstream of the heliopause.

  10. The Existence and Nature of the Interstellar Bow Shock

    NASA Astrophysics Data System (ADS)

    Ben-Jaffel, Lotfi; Strumik, M.; Ratkiewicz, R.; Grygorczuk, J.

    2013-12-01

    We report a new diagnosis of two different states of the local interstellar medium (LISM) near our solar system by using a sensitivity study constrained by several distinct and complementary observations of the LISM, solar wind, and inner heliosphere. Assuming the Interstellar Boundary Explorer (IBEX) He flow parameters for the LISM, we obtain a strength of ~2.7 ± 0.2 μG and a direction pointing away from galactic coordinates (28, 52) ± 3° for the interstellar magnetic field as a result of fitting Voyager 1 and Voyager 2 in situ plasma measurements and IBEX energetic neutral atoms ribbon. When using Ulysses parameters for the LISM He flow, we recently reported the same direction but with a strength of 2.2 ± 0.1 μG. First, we notice that with Ulysses He flow, our solution is in the expected hydrogen deflection plane (HDP). In contrast, for the IBEX He flow, the solution is ~20° away from the corresponding HDP plane. Second, the long-term monitoring of the interplanetary H I flow speed shows a value of ~26 km s-1 measured upwind from the Doppler shift in the strong Lyα sky background emission line. All elements of the diagnosis seem therefore to support Ulysses He flow parameters for the interstellar state. In that frame, we argue that reliable discrimination between superfast, subfast, or superslow states of the interstellar flow should be based on most existing in situ and remote observations used together with global modeling of the heliosphere. For commonly accepted LISM ionization rates, we show that a fast interstellar bow shock should be standing off upstream of the heliopause.

  11. Bow and Oblique Shock Formation in Soap Film

    NASA Astrophysics Data System (ADS)

    Kim, Ildoo; Mandre, Shreyas; Sane, Aakash

    2015-11-01

    In recent years, soap films have been exploited primarily to approximate two-dimensional flows while their three-dimensional character is relatively unattended. An example of the three-dimensional character of the flow in a soap film is the observed Marangoni shock wave when the flow speed exceeds the wave speed. In this study, we investigated the formation of bow and oblique shocks in soap films generated by wedges with different deflection angles. When the wedge deflection angle is small and the film flows fast, oblique shocks are observed. When the oblique shock cannot exists, bow shock is formed upstream the wedge. We characterized the oblique shock angle as a function of the wedge deflection angle and the flow speed, and we also present the criteria for transition between bow and oblique Marangoni shocks in soap films.

  12. Electrostatic waves in the bow shock at Uranus

    NASA Technical Reports Server (NTRS)

    Moses, S. L.; Coroniti, F. V.; Kennel, C. F.; Bagenal, F.; Lepping, R. P.

    1989-01-01

    Electrostatic emissions measured by the Voyager 2 plasma wave detector (PWS) during the inbound crossing of the Uranian bow shock are shown to differ in some aspects from the waves measured during bow shock crossings at Jupiter and Saturn. The wave amplitudes in the foot of the bow shock at Uranus are in general much lower than those detected at the other outer planets due to the unusually enhanced solar wind ion temperature during the crossing. This reduces the effectiveness of wave-particle interactions in heating the incoming electrons. Strong wave emissions are observed in the shock ramp that possibly arise from currents producing a Buneman mode instability. Plasma instrument (PLS) and magnetometer (MAG) measurements reveal a complicated shock structure reminiscent of computer simulations of high-Mach number shocks when the effects of anomalous resistivity are reduced, and are consistent with high ion temperatures restricting the growth of electrostatic waves.

  13. Bow and stern waves triggered by the Moon's shadow boat

    NASA Astrophysics Data System (ADS)

    Liu, J. Y.; Sun, Y. Y.; Kakinami, Y.; Chen, C. H.; Lin, C. H.; Tsai, H. F.

    2011-09-01

    It has been predicted that the Moon's shadow, the cooling region, sweeping over the Earth's atmosphere with a supersonic speed could trigger bow waves since 1970. The longest total solar eclipse within next hundred years occurring on 22 July 2009 sweeps over the Eastern Asia region during the noontime period. An analysis of the Hilbert-Huang transform (HHT) is applied to study ionospheric TEC (total electron content) derived from ground-based GPS receivers in Taiwan and Japan. We not only find the feature of the predicted bow wave but also the stern wave on the equator side of the eclipse path, as well as the stern wake right behind the Moon's shadow boat. The bow and stern waves are formed by acoustic gravity waves of periods about 3 and/or 5 minutes traveling equatorward with a phase speed of about 100 m/s in the ionosphere.

  14. Omohyoid muscle transposition for the treatment of bowed vocal fold.

    PubMed

    Kojima, H; Hirano, S; Shoji, K; Omori, K; Honjo, I

    1996-07-01

    Imperfect glottal closure is usually the most important factor causing dysphonia in patients with bowing of the vocal folds. We have performed laryngeal framework surgery, which allows the medialization of the vocal folds from the outside without creating any scar tissue on them. Over the past 6 years, however, we encountered three cases with marked bowing of the vocal folds that could not be cured by laryngeal framework surgery alone. We used an open laryngeal procedure in these cases, even though such procedures had been considered contraindicated in the treatment of hoarseness. After performing a laryngofissure, we made a small pocket beneath the vocal fold mucosa at the anterior commissure. The superiorly based omohyoid muscle flap was then transposed into the mucosal pocket and sutured to the vocal process. This procedure should be considered an option in treating highly bowed vocal folds. PMID:8678430

  15. Electrostatic waves in the bow shock at Uranus

    SciTech Connect

    Moses, S.L.; Coroniti, F.V.; Kennel, C.F.; Scarf, F.L. ); Bagenal, F. ); Lepping, R.P. ); Quest, K.B. ); Kurth, W.S. )

    1989-10-01

    Electrostatic emissions measured by the Voyager 2 plasma wave detector (PWS) during the inbound crossing of the Uranian bow shock are shown to differ in some aspects from the waves measured during bow shock crossings at Jupiter and Saturn. The wave amplitudes in the foot of the bow shock at Uranus are in general much lower than those detected at the other out planets due to the unusually enhanced solar wind ion temperature during the crossing. This reduces the effectiveness of wave-particle interactions in heating the incoming electrons. Strong wave emissions are observed in the shock ramp that possibly arise from currents producing a Buneman mode instability. Plasma instrument (PLS) and magnetometer (MAG) measurements reveal a complicated shock structure reminiscent of computer simulations of high-Mach number shocks when the effects of anomalous resistivity are reduced, and are consistent with high ion temperatures restricting the growth of electrostatic waves.

  16. EVAPORATION OF ICY PLANETESIMALS DUE TO BOW SHOCKS

    SciTech Connect

    Tanaka, Kyoko K.; Yamamoto, Tetsuo; Tanaka, Hidekazu; Miura, Hitoshi; Nagasawa, Makiko; Nakamoto, Taishi

    2013-02-20

    We present the novel concept of evaporation of planetesimals as a result of bow shocks associated with planetesimals orbiting with supersonic velocities relative to the gas in a protoplanetary disk. We evaluate the evaporation rates of the planetesimals based on a simple model describing planetesimal heating and evaporation by the bow shock. We find that icy planetesimals with radius {approx}>100 km evaporate efficiently even outside the snow line in the stage of planetary oligarchic growth, where strong bow shocks are produced by gravitational perturbations from protoplanets. The obtained results suggest that the formation of gas giant planets is suppressed owing to insufficient accretion of icy planetesimals onto the protoplanet within the {approx}<5 AU disk region.

  17. Maskless direct laser writing with visible light: Breaking through the optical resolving limit with cooperative manipulations of nonlinear reverse saturation absorption and thermal diffusion

    SciTech Connect

    Wei, Jingsong; Wang, Rui

    2014-03-28

    In this work, the resolving limit of maskless direct laser writing is overcome by cooperative manipulation from nonlinear reverse saturation absorption and thermal diffusion, where the nonlinear reverse saturation absorption can induce the formation of below diffraction-limited energy absorption spot, and the thermal diffusion manipulation can make the heat quantity at the central region of energy absorption spot propagate along the thin film thickness direction. The temperature at the central region of energy absorption spot transiently reaches up to melting point and realizes nanolithography. The sample “glass substrate/AgInSbTe” is prepared, where AgInSbTe is taken as nonlinear reverse saturation absorption thin film. The below diffraction-limited energy absorption spot is simulated theoretically and verified experimentally by near-field spot scanning method. The “glass substrate/Al/AgInSbTe” sample is prepared, where the Al is used as thermal conductive layer to manipulate the thermal diffusion channel because the thermal diffusivity coefficient of Al is much larger than that of AgInSbTe. The direct laser writing is conducted by a setup with a laser wavelength of 650 nm and a converging lens of NA=0.85, the lithographic marks with a size of about 100 nm are obtained, and the size is only about 1/10 the incident focused spot. The experimental results indicate that the cooperative manipulation from nonlinear reverse saturation absorption and thermal diffusion is a good method to realize nanolithography in maskless direct laser writing with visible light.

  18. Total wrist arthrodesis using bowed crossed K-wires.

    PubMed

    Minami, A; Kato, H; Iwasaki, N

    1999-08-01

    A method of total wrist arthrodesis using a combination of autogenous iliac crest bone graft and "bowed" crossed Kirschner wires is described. The method of bowing the K-wires results in a compressive force on the iliac bone graft. This technique resulted in bony union of 22 wrists in 20 patients. The mean time to union was 12 weeks (range, 8-14 weeks). There were no major postoperative complications. The advantages of this technique are its simplicity, versatility, and reliability which mean that special internal fixation devices are not needed. PMID:10473146

  19. High-temperature Processing of Solids through Solar Nebular Bow Shocks: 3D Radiation Hydrodynamics Simulations with Particles

    NASA Astrophysics Data System (ADS)

    Boley, A. C.; Morris, M. A.; Desch, S. J.

    2013-10-01

    A fundamental, unsolved problem in solar system formation is explaining the melting and crystallization of chondrules found in chondritic meteorites. Theoretical models of chondrule melting in nebular shocks have been shown to be consistent with many aspects of thermal histories inferred for chondrules from laboratory experiments; but, the mechanism driving these shocks is unknown. Planetesimals and planetary embryos on eccentric orbits can produce bow shocks as they move supersonically through the disk gas, and are one possible source of chondrule-melting shocks. We investigate chondrule formation in bow shocks around planetoids through three-dimensional radiation hydrodynamics simulations. A new radiation transport algorithm that combines elements of flux-limited diffusion and Monte Carlo methods is used to capture the complexity of radiative transport around bow shocks. An equation of state that includes the rotational, vibrational, and dissociation modes of H2 is also used. Solids are followed directly in the simulations and their thermal histories are recorded. Adiabatic expansion creates rapid cooling of the gas, and tail shocks behind the embryo can cause secondary heating events. Radiative transport is efficient, and bow shocks around planetoids can have luminosities ~few× 10-8 L ⊙. While barred and radial chondrule textures could be produced in the radiative shocks explored here, porphyritic chondrules may only be possible in the adiabatic limit. We present a series of predicted cooling curves that merit investigation in laboratory experiments to determine whether the solids produced by bow shocks are represented in the meteoritic record by chondrules or other solids.

  20. HIGH-TEMPERATURE PROCESSING OF SOLIDS THROUGH SOLAR NEBULAR BOW SHOCKS: 3D RADIATION HYDRODYNAMICS SIMULATIONS WITH PARTICLES

    SciTech Connect

    Boley, A. C.; Morris, M. A.; Desch, S. J.

    2013-10-20

    A fundamental, unsolved problem in solar system formation is explaining the melting and crystallization of chondrules found in chondritic meteorites. Theoretical models of chondrule melting in nebular shocks have been shown to be consistent with many aspects of thermal histories inferred for chondrules from laboratory experiments; but, the mechanism driving these shocks is unknown. Planetesimals and planetary embryos on eccentric orbits can produce bow shocks as they move supersonically through the disk gas, and are one possible source of chondrule-melting shocks. We investigate chondrule formation in bow shocks around planetoids through three-dimensional radiation hydrodynamics simulations. A new radiation transport algorithm that combines elements of flux-limited diffusion and Monte Carlo methods is used to capture the complexity of radiative transport around bow shocks. An equation of state that includes the rotational, vibrational, and dissociation modes of H{sub 2} is also used. Solids are followed directly in the simulations and their thermal histories are recorded. Adiabatic expansion creates rapid cooling of the gas, and tail shocks behind the embryo can cause secondary heating events. Radiative transport is efficient, and bow shocks around planetoids can have luminosities ∼few× 10{sup –8} L{sub ☉}. While barred and radial chondrule textures could be produced in the radiative shocks explored here, porphyritic chondrules may only be possible in the adiabatic limit. We present a series of predicted cooling curves that merit investigation in laboratory experiments to determine whether the solids produced by bow shocks are represented in the meteoritic record by chondrules or other solids.

  1. DNA-directed DNA polymerase and strand displacement activity of the reverse transcriptase encoded by the R2 retrotransposon.

    PubMed

    Kurzynska-Kokorniak, Anna; Jamburuthugoda, Varuni K; Bibillo, Arkadiusz; Eickbush, Thomas H

    2007-11-23

    R2 elements are non-long terminal repeat (non-LTR) retrotransposons with a single open reading-frame encoding reverse transcriptase, DNA endonuclease and nucleic acid-binding domains. The elements are specialized for insertion into the 28 S rRNA genes of many animal phyla. The R2-encoded activities initiate retrotransposition by sequence-specific cleavage of the 28 S gene target site and the utilization of the released DNA 3' end to prime reverse transcription (target primed reverse transcription). The activity of the R2 polymerase on RNA templates has been shown to differ from retroviral reverse transcriptases (RTs) in a number of properties. We demonstrate that the R2-RT is capable of efficiently utilizing single-stranded DNA (ssDNA) as a template. The processivity of the enzyme on ssDNA templates is higher than its processivity on RNA templates. This finding suggests that R2-RT is also capable of synthesizing the second DNA strand during retrotransposition. However, R2-RT lacks the RNAse H activity that is typically used by retroviral and LTR-retrotransposon RTs to remove the RNA strand before the first DNA strand is used as template. Remarkably, R2-RT can displace RNA strands that are annealed to ssDNA templates with essentially no loss of processivity. Such strand displacement activity is highly unusual for a DNA polymerase. Thus the single R2 protein contains all the activities needed to make a double-stranded DNA product from an RNA transcript. Finally, during these studies we found an unexpected property of the highly sequence-specific R2 endonuclease domain. The endonuclease can non-specifically cleave ssDNA at a junction with double-stranded DNA. This activity suggests that second-strand cleavage of the target site may not be sequence specific, but rather is specified by a single-stranded region generated when the first DNA strand is used to prime reverse transcription.

  2. Multipoint observations and simulation of the effects of Earth's bow shock on magnetic clouds' structure and geoeffectiveness

    NASA Astrophysics Data System (ADS)

    Fontaine, Dominique; Turc, Lucile; Savoini, Philippe

    2015-04-01

    Magnetic clouds represent a sub-class of coronal mass ejection (CME) capable to trigger very strong storms in the terrestrial environment. Their magnetic structure can be described as a flux rope and statistical studies show a dependence of their geoeffectiveness on the orientation of this flux rope relative to the terrestrial magnetic field. However, this primary dependence does not fully explain by itself the storm triggering and strength. Other effects as the cloud's sheath or events on its leading or trailing edges have been discussed. We investigate here the role of the bow shock that magnetic clouds cross before interacting with the magnetosphere. From observations in the solar wind upstream of the bow shock (ACE) and downstream (CLUSTER), we show that the bow show may strongly modify the cloud's magnetic structure and even cause the reversal of the IMF Bz component: this is crucial for the development of geomagnetic activity inside the magnetosphere. We show that this modification is related to the shock configuration (quasi-parallel, quasi-perpendicular) and we derive the upstream conditions leading to strong downstream distortions. In addition, we run hybrid simulations to analyze the different plasma behaviours in both configurations. In particular we discuss the results concerning the distribution of dynamical, thermal and magnetic pressures and the associated forces.

  3. Statistical analysis of diffuse ion events upstream of the Earth's bow shock

    NASA Technical Reports Server (NTRS)

    Trattner, K. J.; Mobius, E.; Scholer, M.; Klecker, B.; Hilchenbach, M.; Luehr, H.

    1994-01-01

    A statistical study of diffuse energetic ion events and their related waves upstream of the Earth's bow shock was performed using data from the Active Magnetospheric Particle Tracer Explorers/Ion Release Module (AMPTE/IRM) satellite over two 5-month periods in 1984 and 1985. The data set was used to test the assumption in the self-consistent model of the upstream wave and particle populations by Lee (1982) that the particle acceleration through hydromagnetic waves and the wave generation are directly coupled. The comparison between the observed wave power and the wave power predicted on the observed energetic particle energy density and solar wind parameters results in a high correlation coefficient of about 0.89. The intensity of diffuse ions falls off approximately exponentially with the distance upstream from the bow shock parallel to the magnetic field with e-folding distances which vary from approximately 3.3 R(sub E) to approximately 11.7 R(sub E) over the energy range from 10 keV/e to 67.3 keV/e for both protons and alpha particles. After normalizing the upstream particle densities to zero bow shock distance by using these exponential variations, a good correlation (0.7) of the density of the diffuse ions with the solar wind density was found. This supports the suggestion that the solar wind is the source of the diffuse ions. Furthermore, the spectral slope of the diffuse ions correlates well with the solar wind velocity component in the direction of the interplanetary magnetic field (0.68 and 0.66 for protons and alpha particles) which concurs with the notion that the solar wind plays an important role in the acceleration of the upstream particles.

  4. Direct detection of viable bacteria, molds, and yeasts by reverse transcriptase PCR in contaminated milk samples after heat treatment.

    PubMed

    Vaitilingom, M; Gendre, F; Brignon, P

    1998-03-01

    A fast, sensitive, and target contaminant-modulable method was developed to detect viable bacteria, molds, and yeasts after heat treatment. By reverse transcriptase PCR with elongation factor gene (EF-Tu or EF-1 alpha)-specific primers, the detection level was 10 cells ml of milk-1. The simplicity and rapidity (4 h) of the procedure suggests that this method may be easily transposable to other foods and other contaminants. PMID:9501455

  5. Direct Detection of Viable Bacteria, Molds, and Yeasts by Reverse Transcriptase PCR in Contaminated Milk Samples after Heat Treatment

    PubMed Central

    Vaitilingom, Marc; Gendre, Francois; Brignon, Pierre

    1998-01-01

    A fast, sensitive, and target contaminant-modulable method was developed to detect viable bacteria, molds, and yeasts after heat treatment. By reverse transcriptase PCR with elongation factor gene (EF-Tu or EF-1α)-specific primers, the detection level was 10 cells ml of milk−1. The simplicity and rapidity (4 h) of the procedure suggests that this method may be easily transposable to other foods and other contaminants. PMID:9501455

  6. Directly observed reversible shape changes and hemoglobin stratification during centrifugation of human and Amphiuma red blood cells.

    PubMed

    Hoffman, Joseph F; Inoué, Shinya

    2006-02-21

    This paper describes changes that occur in human and Amphiuma red blood cells observed during centrifugation with a special microscope. Dilute suspensions of cells were layered, in a centrifuge chamber, above an osmotically matched dense solution, containing Nycodenz, Ficoll, or Percoll (Pharmacia) that formed a density gradient that allowed the cells to slowly settle to an equilibrium position. Biconcave human red blood cells moved downward at low forces with minimum wobble. The cells oriented vertically when the force field was increased and Hb sedimented as the lower part of each cell became bulged and assumed a "bag-like" shape. The upper centripetal portion of the cell became thinner and remained biconcave. These changes occurred rapidly and were completely reversible upon lowering the centrifugal force. Bag-shaped cells, upon touching red cells in rouleau, immediately reverted to biconcave disks as they flipped onto a stack. Amphiuma red cells displayed a different type of reversible stratification and deformation at high force fields. Here the cells became stretched, with the nucleus now moving centrifugally, the Hb moving centripetally, and the bottom of the cells becoming thinner and clear. Nevertheless, the distribution of the marginal bands at the cells' rim was unchanged. We conclude that centrifugation, per se, while changing a red cell's shape and the distribution of its intracellular constituents, does so in a completely reversible manner. Centrifugation of red cells harboring altered or missing structural elements could provide information on shape determinants that are still unexplained. PMID:16477016

  7. 41. BOW SPACES (YN OFFICES, AYN OFFICES & DECK SHOP, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. BOW SPACES (YN OFFICES, AYN OFFICES & DECK SHOP, LAUNDRY & BOS'N STORES), WITH HATCH TO PAINT LOCKER AT LEFT. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  8. 20. DECK ABOVE CREW'S BERTHING, LOOKING TOWARDS THE BOW, SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. DECK ABOVE CREW'S BERTHING, LOOKING TOWARDS THE BOW, SHOWING BOAT WINCH IN FOREGROUND, BEHIND IT IS THE FIDLY AND TO EITHER SIDE OF THE FIDLY IS A RHI (RIGID HULL INFLATABLE). - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  9. Threequarter view of port bow of White Holly (WLM 543) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Three-quarter view of port bow of White Holly (WLM 543) on left, White Sage (WLM 544) on right. Note differences between the two. - U.S. Coast Guard Cutter WHITE HOLLY, U.S. Coast Guard 8th District Base, 4640 Urquhart Street, New Orleans, Orleans Parish, LA

  10. Application of Bow-tie methodology to improve patient safety.

    PubMed

    Abdi, Zhaleh; Ravaghi, Hamid; Abbasi, Mohsen; Delgoshaei, Bahram; Esfandiari, Somayeh

    2016-05-01

    Purpose - The purpose of this paper is to apply Bow-tie methodology, a proactive risk assessment technique based on systemic approach, for prospective analysis of the risks threatening patient safety in intensive care unit (ICU). Design/methodology/approach - Bow-tie methodology was used to manage clinical risks threatening patient safety by a multidisciplinary team in the ICU. The Bow-tie analysis was conducted on incidents related to high-alert medications, ventilator associated pneumonia, catheter-related blood stream infection, urinary tract infection, and unwanted extubation. Findings - In total, 48 potential adverse events were analysed. The causal factors were identified and classified into relevant categories. The number and effectiveness of existing preventive and protective barriers were examined for each potential adverse event. The adverse events were evaluated according to the risk criteria and a set of interventions were proposed with the aim of improving the existing barriers or implementing new barriers. A number of recommendations were implemented in the ICU, while considering their feasibility. Originality/value - The application of Bow-tie methodology led to practical recommendations to eliminate or control the hazards identified. It also contributed to better understanding of hazard prevention and protection required for safe operations in clinical settings. PMID:27142951

  11. The Failure of Speech in "The Ox-Bow Incident"

    ERIC Educational Resources Information Center

    Houghton, Donald E.

    1970-01-01

    In The Ox-Bow Incident," author Walter Van Tilburg Clark dramatizes the truth that speakers who whould urge men to think before acting need at least as much courage as those who would act first and think later." (Author/RD)

  12. 126. AERIAL FORWARD VIEW OF ENCLOSED HURRICANE BOW WITH FLIGHT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    126. AERIAL FORWARD VIEW OF ENCLOSED HURRICANE BOW WITH FLIGHT DECK GUN MOUNTS REMOVED AND ANGLED FLIGHT DECK. 1 OCTOBER 1956. (NATIONAL ARCHIVES NO. 80-G-1001445) - U.S.S. HORNET, Puget Sound Naval Shipyard, Sinclair Inlet, Bremerton, Kitsap County, WA

  13. Significance of torsion modes in bowed-string dynamics

    NASA Astrophysics Data System (ADS)

    Inacio, Octavio; Antunes, Jose; Henrique, Luis

    2002-11-01

    Several aspects of bowed-string dynamics are still inadequately clarified. The importance of torsion modes on the motion regimes is one such issue. Experiments involving torsion are difficult and most of the results available pertain to numerical simulations. The authors' approach differs from previous efforts in two main aspects: (1) the development of a computational method distinct from the wave-propagation approach pioneered by McIntyre, Schumacher, and Woodhouse and (2) an extensive and systematic analysis of the coupling between torsion and transverse motions is performed. The numerical simulations are based on a modal representation of the unconstrained string and a computational approach for friction that enables accurate representations of the stick-slip forces and of the string dynamics, in both time and space. Many relevant aspects of the bowed-string can be readily implemented, including string inharmonic behavior, finite bow-width, and torsion effects. Concerning the later aspect, a realistic range of the torsional to transverse wave-speed ratio is investigated, for several values of the bow velocity and normal force. Results suggest that torsion modes can effect both transient durations and steady state regimes, in particular when the above-mentioned ratio is <4. Gut strings should then be particularly prone to torsion effects.

  14. Application of Bow-tie methodology to improve patient safety.

    PubMed

    Abdi, Zhaleh; Ravaghi, Hamid; Abbasi, Mohsen; Delgoshaei, Bahram; Esfandiari, Somayeh

    2016-05-01

    Purpose - The purpose of this paper is to apply Bow-tie methodology, a proactive risk assessment technique based on systemic approach, for prospective analysis of the risks threatening patient safety in intensive care unit (ICU). Design/methodology/approach - Bow-tie methodology was used to manage clinical risks threatening patient safety by a multidisciplinary team in the ICU. The Bow-tie analysis was conducted on incidents related to high-alert medications, ventilator associated pneumonia, catheter-related blood stream infection, urinary tract infection, and unwanted extubation. Findings - In total, 48 potential adverse events were analysed. The causal factors were identified and classified into relevant categories. The number and effectiveness of existing preventive and protective barriers were examined for each potential adverse event. The adverse events were evaluated according to the risk criteria and a set of interventions were proposed with the aim of improving the existing barriers or implementing new barriers. A number of recommendations were implemented in the ICU, while considering their feasibility. Originality/value - The application of Bow-tie methodology led to practical recommendations to eliminate or control the hazards identified. It also contributed to better understanding of hazard prevention and protection required for safe operations in clinical settings.

  15. 18. FROM DECK ABOVE CO'S STATEROOM, LOOKING TOWARDS BOW, AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. FROM DECK ABOVE CO'S STATEROOM, LOOKING TOWARDS BOW, AT DECK ABOVE PILOT HOUSE AND BEYOND IS MAST. - U.S. Coast Guard Cutter WHITE LUPINE, U.S. Coast Guard Station Rockland, east end of Tillson Avenue, Rockland, Knox County, ME

  16. 20. FROM DECK ABOVE CREW'S BERTHING, LOOKING TOWARDS THE BOW, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. FROM DECK ABOVE CREW'S BERTHING, LOOKING TOWARDS THE BOW, SHOWING WINCH FIDLY, STACK, AND UPPER DECKS. TO EITHER SIDE OF THE FIDLY IS A RHI (RIGID HULL INFLATABLE) AND CRANES. - U.S. Coast Guard Cutter WHITE LUPINE, U.S. Coast Guard Station Rockland, east end of Tillson Avenue, Rockland, Knox County, ME

  17. 41. AUGUST 9, 1948 BOW STARBOARD VIEW. TAKEN SOON AFTER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. AUGUST 9, 1948 BOW STARBOARD VIEW. TAKEN SOON AFTER COMMISSIONING INTO U.S. COAST GUARD. NOTE ORIGINAL CRANE AND HOISTING MECHANISM AND TWO ADDITIONAL PILES (SPUDS) THAT DROPPED INTO THE MUD BOTTOM TO STEADY THE VESSEL WHILE WORKING. - U.S. Coast Guard Cutter WHITE PINE, U.S. Coast Guard 8th District Base, South Broad Street, Mobile, Mobile County, AL

  18. Detail of bow showing new frames and planking on starboard ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of bow showing new frames and planking on starboard side. Note oak trunnels used to fasten the planks to the frames. Frames are oak; planking is yellow pine. - Schooner ERNESTINA, New Bedford Whaling National Historical Park State Pier, New Bedford, Bristol County, MA

  19. 4. DETAIL VIEW, LOOKING SOUTH, ACROSS HULL NEAR BOW END, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. DETAIL VIEW, LOOKING SOUTH, ACROSS HULL NEAR BOW END, TOP OF FORWARD STARBOARD CARGO HATCH IN FOREGROUND, OPENING FOR PORT HATCH BEYOND Edward Larrabee, photographer, November 1984 - Shooters Island, Ships Graveyard, Vessel No. 54, Newark Bay, Staten Island (subdivision), Richmond County, NY

  20. The activated face-bow: simple, safe, extraoral traction.

    PubMed

    Magni, F

    1979-02-01

    A simple and safe extraoral traction model is described. This consists of a face-bow with activated outer arms and a neck strap or headgear without any elastic force, such as rubber bands, elastic ribbons, coil springs, etc. The appliance cannot be withdrawn from the mouth by acident; therefore, the patient is protected from possible injuries.

  1. 30. View of main deck at bow (looking aft from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. View of main deck at bow (looking aft from samson post, upper deck removed), showing anchor windlass (left foreground), head (right foregound), and forward deckhouse; weather canopy overhead not an original or permanent feature - Schooner WAWONA, 1018 Valley Street, Seattle, King County, WA

  2. A Study of Uranus' Bow Shock Motions Using Langmuir Waves

    NASA Technical Reports Server (NTRS)

    Xue, S.; Cairns, I. H.; Smith, C. W.; Gurnett, D. A.

    1996-01-01

    During the Voyager 2 flyby of Uranus, strong electron plasma oscillations (Langmuir waves) were detected by the plasma wave instrument in the 1.78-kHz channel on January 23-24, 1986, prior to the inbound bow shock crossing. Langmuir waves are excited by energetic electrons streaming away from the bow shock. The goal of this work is to estimate the location and motion of Uranus' bow shock using Langmuir wave data, together with the spacecraft positions and the measured interplanetary magnetic field. The following three remote sensing analyses were performed: the basic remote sensing method, the lag time method, and the trace-back method. Because the interplanetary magnetic field was highly variable, the first analysis encountered difficulties in obtaining a realistic estimation of Uranus' bow shock motion. In the lag time method developed here, time lags due to the solar wind's finite convection speed are taken into account when calculating the shock's standoff distance. In the new trace-back method, limits on the standoff distance are obtained as a function of time by reconstructing electron paths. Most of the results produced by the latter two analyses are consistent with predictions based on the standard theoretical model and the measured solar wind plasma parameters. Differences between our calculations and the theoretical model are discussed.

  3. 23. VIEW FROM STARBOARD BOW OF ALABAMA AS 'ALABAMIAN.' Uncopyrighted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. VIEW FROM STARBOARD BOW OF ALABAMA AS 'ALABAMIAN.' Uncopyrighted 3-1/2'x5-5/8' postcard; image taken on station in Gulf of Mexico, c. 1930? - Pilot Schooner "Alabama", Moored in harbor at Vineyard Haven, Vineyard Haven, Dukes County, MA

  4. 36. VIEW OF VESSEL IN DRYDOCK FROM OFF PORT BOW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. VIEW OF VESSEL IN DRYDOCK FROM OFF PORT BOW Note by Robert S. Douglas written on back of original print: 'ALABAMA taken in drydock in Mobile 1966 all 10 photos this size.' Original 5'x5' photograph taken by Robert S. Douglas, 1966 - Pilot Schooner "Alabama", Moored in harbor at Vineyard Haven, Vineyard Haven, Dukes County, MA

  5. 25. VIEW OF ALABAMA (ALABAMIAN) FROM OFF PORT BOW; VESSEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. VIEW OF ALABAMA (ALABAMIAN) FROM OFF PORT BOW; VESSEL AT ANCHOR ON STATION IN GULF OF MEXICO WITH MOTOR BOAT TIED AT STERN Original 4-3/4'x6-3/4' photograph taken c. 1930? - Pilot Schooner "Alabama", Moored in harbor at Vineyard Haven, Vineyard Haven, Dukes County, MA

  6. 16. Detail, northeast facade, operator's bow window and tower; note ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Detail, northeast facade, operator's bow window and tower; note condition of slates on tower skirt roof, missing section of gutter at left side of skirt roof, missing window panes; note also knee braces carried on masonry ancons; view to southwest, 90mm lens. - Southern Pacific Depot, 559 El Camino Real, San Carlos, San Mateo County, CA

  7. Compositional bowing of band energies and their deformation potentials in strained InGaAs ternary alloys: A first-principles study

    SciTech Connect

    Khomyakov, Petr A.; Luisier, Mathieu; Schenk, Andreas

    2015-08-10

    Using first-principles calculations, we show that the conduction and valence band energies and their deformation potentials exhibit a non-negligible compositional bowing in strained ternary semiconductor alloys such as InGaAs. The electronic structure of these compounds has been calculated within the framework of local density approximation and hybrid functional approach for large cubic supercells and special quasi-random structures, which represent two kinds of model structures for random alloys. We find that the predicted bowing effect for the band energy deformation potentials is rather insensitive to the choice of the functional and alloy structural model. The direction of bowing is determined by In cations that give a stronger contribution to the formation of the In{sub x}Ga{sub 1−x}As valence band states with x ≳ 0.5, compared to Ga cations.

  8. Double tibial osteotomy for bow leg patients: A case series

    PubMed Central

    Nazem, Khalilollah; Fouladi, Arash; Chinigarzadeh, Mozhdeh

    2013-01-01

    Background: High tibia osteotomy (HTO) is a common surgical operation for correction of genu varum deformity. In some patients, there are concurrent tibia vara and genu varum (bow leg). This study aimed to consider the possibility of better correction of bow leg deformity after double level tibial osteotomy (DLTO). Materials and Methods: A case series of 10 patients of genu varum in addition to tibia vara (bow leg) deformity who were referred to orthopedic ward of an academic hospital of Isfahan- Iran during 2009–2011 were included in the study. The mean age was 17.3 ± 3.1 years and all of them underwent DLTO. The results of treatment have been assessed based on clinical and radiological parameters before and after surgery. Results: The mean pre- and post operative values for Tibia-Femoral Angle, Medial Proximal of Tibia Angle (MPTA), and Lateral Distal of Tibia Angle (LDTA) were 18.13 ± 3.05° vs. 3.93 ± 0.66°, 79.13 ± 3.4° vs. 89.7 ± 1.8° and 96.40 ± 1.8° vs. 88.73 ± 3.0° respectively (P < 0.05). Improvement of all radiological parameters was meaningful. Seventy three percent of patients had normal mechanical axis of limb after surgery. The remaining cases had varus deformity in distal femur that was corrected by valgus supracondylar osteotomy in an additional operation. Limited range of motion (ROM) near knee and ankle was not observed. Conclusion: DLTO correct bow leg deformity in the point of alignment of limb and paralleling of knee and ankle joint more effectively. This method can be used in metabolic and congenital bow leg which deformities are present in throughout of the lower limb. We described this technique for the first time. PMID:24523802

  9. Static model of a violin bow: influence of camber and hair tension on mechanical behavior.

    PubMed

    Ablitzer, Frédéric; Dalmont, Jean-Pierre; Dauchez, Nicolas

    2012-01-01

    Experienced bow makers empirically know the influence of wood, tapering, and camber on the playing and tonal qualities of a bow. However, the way each parameter affects the bow mechanical behavior is not clearly established. An in-plane finite element model is developed to highlight the link between the adjustable design parameters and the mechanical behavior of a bow. This model takes into account geometric nonlinearity as well as compliance of the hair. Its validity is discussed from measurements on a bow. Results from simulations are compared to experimental results from previous studies. The consequences of adjusting hair tension and camber are then investigated. PMID:22280700

  10. Static model of a violin bow: influence of camber and hair tension on mechanical behavior.

    PubMed

    Ablitzer, Frédéric; Dalmont, Jean-Pierre; Dauchez, Nicolas

    2012-01-01

    Experienced bow makers empirically know the influence of wood, tapering, and camber on the playing and tonal qualities of a bow. However, the way each parameter affects the bow mechanical behavior is not clearly established. An in-plane finite element model is developed to highlight the link between the adjustable design parameters and the mechanical behavior of a bow. This model takes into account geometric nonlinearity as well as compliance of the hair. Its validity is discussed from measurements on a bow. Results from simulations are compared to experimental results from previous studies. The consequences of adjusting hair tension and camber are then investigated.

  11. Particle acceleration during interactions between transient ion foreshock phenomena and Earth's bow shock

    NASA Astrophysics Data System (ADS)

    Turner, Drew; Angelopoulos, Vassilis; Wilson, Lynn; Hietala, Heli; Omidi, Nick; Masters, Adam

    2014-05-01

    Foreshocks are regions upstream of supercritical astrophysical shock waves that are in communication with the shock via suprathermal charged particles that have been energized and reflected by the shock and are counter-streaming into the incident plasma. These regions form upstream of the quasi-parallel region of the shock, in which the angle between the magnetic field in the incident plasma and the shock normal direction is less than ~40 deg. The relative drift between the reflected suprathermal particles and the incident bulk flow is a source of free energy, which is capable of producing a variety of kinetic plasma instabilities and enhanced wave activity. Simulations and observations of Earth's and other planetary foreshocks have shown that large-scale transient phenomena can also develop due to nonlinear processes and interactions between foreshock particles and discontinuities in the incident solar wind. Several of these transient ion foreshock phenomena (TIFP), such as short large-amplitude magnetic structures (SLAMS), hot flow anomalies (HFAs), and foreshock bubbles (FBs), can result in the development of nonlinear wave activity and additional shocks upstream of the main bow shock. We present in situ observations, made by NASA's THEMIS mission, of ion and electron distributions from within and without SLAMS, HFAs, and FBs, examining the particle heating and acceleration taking place within those TIFP. The observations are compared to theoretical expectations for shock-drift acceleration, Fermi acceleration, and energy diffusion via wave-particle interactions. Our preliminary results show that SLAMS, HFAs, and FBs can be ideal particle accelerators. Finally, we develop an understanding for the upper energy limits for ion and electron acceleration in each of these TIFP at Earth's bow shock and use this to investigate how TIFP may accelerate particles at other astrophysical shocks, such as planetary and astrospherical bow shocks, shocks in stellar winds, and

  12. GYROSURFING ACCELERATION OF IONS IN FRONT OF EARTH's QUASI-PARALLEL BOW SHOCK

    SciTech Connect

    Kis, Arpad; Lemperger, Istvan; Wesztergom, Viktor; Agapitov, Oleksiy; Krasnoselskikh, Vladimir; Dandouras, Iannis E-mail: Kis.Arpad@csfk.mta.hu

    2013-07-01

    It is well known that shocks in space plasmas can accelerate particles to high energies. However, many details of the shock acceleration mechanism are still unknown. A critical element of shock acceleration is the injection problem; i.e., the presence of the so called seed particle population that is needed for the acceleration to work efficiently. In our case study, we present for the first time observational evidence of gyroresonant surfing acceleration in front of Earth's quasi-parallel bow shock resulting in the appearance of the long-suspected seed particle population. For our analysis, we use simultaneous multi-spacecraft measurements provided by the Cluster spacecraft ion (CIS), magnetic (FGM), and electric field and wave instrument (EFW) during a time period of large inter-spacecraft separation distance. The spacecraft were moving toward the bow shock and were situated in the foreshock region. The results show that the gyroresonance surfing acceleration takes place as a consequence of interaction between circularly polarized monochromatic (or quasi-monochromatic) transversal electromagnetic plasma waves and short large amplitude magnetic structures (SLAMSs). The magnetic mirror force of the SLAMS provides the resonant conditions for the ions trapped by the waves and results in the acceleration of ions. Since wave packets with circular polarization and different kinds of magnetic structures are very commonly observed in front of Earth's quasi-parallel bow shock, the gyroresonant surfing acceleration proves to be an important particle injection mechanism. We also show that seed ions are accelerated directly from the solar wind ion population.

  13. O+ ion beams reflected below the Martian bow shock: MAVEN observations

    NASA Astrophysics Data System (ADS)

    Masunaga, K.; Seki, K.; Brain, D. A.; Fang, X.; Dong, Y.; Jakosky, B. M.; McFadden, J. P.; Halekas, J. S.; Connerney, J. E. P.

    2016-04-01

    We investigate a generation mechanism of O+ ion beams observed above the Martian bow shock by analyzing ion velocity distribution functions (VDFs) measured by the Suprathermal and Thermal Ion Composition instrument on the Mars Atmosphere and Volatile Evolution (MAVEN) spacecraft. In the solar wind near Mars, MAVEN often observes energetic O+ ion beams (~10 keV or higher). Accompanied with the O+ ion beam events, we sometimes observe characteristic ion VDFs in the magnetosheath: a partial ring distribution. The partial ring distribution corresponds to pickup ions with a finite initial velocity (i.e., not newborn pickup ions), and its phase space density is much smaller than that of local pickup O+ ions of the magnetosheath. Thus, the partial ring distribution is most likely produced by the reflection of pickup O+ ions precipitating from the upstream solar wind below the bow shock. After being injected into the magnetosheath from the solar wind, the precipitating O+ ions are subject to the significantly enhanced magnetic field in this region and start to gyrate around the guiding center of the plasma frame in the magnetosheath. Consequently, a part of precipitating O+ ions are reflected back to the solar wind, generating O+ beams in the solar wind. The beams direct quasi-sunward near the subsolar region but have large angle with respect to the sunward direction at high solar zenith angles (>50°). The reflected O+ beams are accelerated by the convection electric field of the solar wind and may escape Mars.

  14. 75 FR 33802 - City of Broken Bow, OK; Broken Bow Re-Regulation Dam; Hydropower Project; Notice of Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... in or Eligible for Inclusion in the National Register of Historic Places June 8, 2010. Rule 2010 of... eligible for inclusion in, the National Register of Historic Places at the Broken Bow Re-Regulation Dam... list for the above-captioned proceeding may request inclusion on the restricted service list, or...

  15. Sequential Polarity-Reversing Circuit

    NASA Technical Reports Server (NTRS)

    Labaw, Clayton C.

    1994-01-01

    Proposed circuit reverses polarity of electric power supplied to bidirectional dc motor, reversible electro-mechanical actuator, or other device operating in direction depending on polarity. Circuit reverses polarity each time power turned on, without need for additional polarity-reversing or direction signals and circuitry to process them.

  16. Investigating the function of play bows in adult pet dogs (Canis lupus familiaris).

    PubMed

    Byosiere, Sarah-Elizabeth; Espinosa, Julia; Smuts, Barbara

    2016-04-01

    Play bows are a common, highly stereotyped canine behavior widely considered to be a 'play signal,' but only one study has researched their function. Bekoff (1995) found that play bows function as behavioral modifiers to help clarify playful intent before or after easily misinterpretable behaviors, such as bite-shakes. To further examine the function of play bows, the current study analyzed five types of behaviors displayed by the bower and the partner immediately before and after a play bow during dyadic play. We found that play bows most often occurred after a brief pause in play. Synchronous behaviors by the bower and the partner, or vulnerable/escape behaviors by the bower (such as running away) and complementary offensive behaviors by the partner (such as chasing) occurred most often after the play bow. These results indicate that during adult dog dyadic play, play bows function to reinitiate play after a pause rather than to mediate offensive or ambiguous actions. PMID:26923096

  17. Deceleration of the solar wind upstream from the earth's bow shock and the origin of diffuse upstream ions

    NASA Technical Reports Server (NTRS)

    Bame, S. J.; Asbridge, J. R.; Feldman, W. C.; Gosling, J. T.; Paschmann, G.; Skopke, N.

    1980-01-01

    Observations with the Los Alamos Scientific Laboratory/Max-Planck-Institut crossed-fan solar wind ion experiment on ISEE I reveal that the solar wind is decelerated and deflected away from the direction of the earth's bow shock as it enters that portion of the upstream region populated by diffuse bow shock ions and long-period (10-60 s) waves. Typically, the average directed velocity vector changes by 7-10 km/s as it enters the wave region. At times, average speed changes as large as 25-40 km/s are observed. Superposed upon these changes in average flow speed are large amplitude (+ or - 15) fluctuations in flow speed associated with the waves themselves. The observations suggest that the solar wind deceleration is the result of momentum transfer from reflected bow shock ions to the wind via the long-period waves as the reflected ion beams go unstable. The broad angular distributions of the diffuse ions thus appear to be produced as a consequence of the disruption of reflected ion beams.

  18. Analytic MHD Theory for Earth's Bow Shock at Low Mach Numbers

    NASA Technical Reports Server (NTRS)

    Grabbe, Crockett L.; Cairns, Iver H.

    1995-01-01

    A previous MHD theory for the density jump at the Earth's bow shock, which assumed the Alfven M(A) and sonic M(s) Mach numbers are both much greater than 1, is reanalyzed and generalized. It is shown that the MHD jump equation can be analytically solved much more directly using perturbation theory, with the ordering determined by M(A) and M(s), and that the first-order perturbation solution is identical to the solution found in the earlier theory. The second-order perturbation solution is calculated, whereas the earlier approach cannot be used to obtain it. The second-order terms generally are important over most of the range of M(A) and M(s) in the solar wind when the angle theta between the normal to the bow shock and magnetic field is not close to 0 deg or 180 deg (the solutions are symmetric about 90 deg). This new perturbation solution is generally accurate under most solar wind conditions at 1 AU, with the exception of low Mach numbers when theta is close to 90 deg. In this exceptional case the new solution does not improve on the first-order solutions obtained earlier, and the predicted density ratio can vary by 10-20% from the exact numerical MHD solutions. For theta approx. = 90 deg another perturbation solution is derived that predicts the density ratio much more accurately. This second solution is typically accurate for quasi-perpendicular conditions. Taken together, these two analytical solutions are generally accurate for the Earth's bow shock, except in the rare circumstance that M(A) is less than or = 2. MHD and gasdynamic simulations have produced empirical models in which the shock's standoff distance a(s) is linearly related to the density jump ratio X at the subsolar point. Using an empirical relationship between a(s) and X obtained from MHD simulations, a(s) values predicted using the MHD solutions for X are compared with the predictions of phenomenological models commonly used for modeling observational data, and with the predictions of a

  19. Validation and scopolamine-reversal of latent learning in the water maze utilizing a revised direct platform placement procedure.

    PubMed

    Malin, David H; Schaar, Krystal L; Izygon, Jonathan J; Nghiem, Duyen M; Jabitta, Sikirat Y; Henceroth, Mallori M; Chang, Yu-Hsuan; Daggett, Jenny M; Ward, Christopher P

    2015-08-01

    The Morris water maze is routinely used to explore neurobiological mechanisms of working memory. Humans can often acquire working memory relevant to performing a task by mere sensory observation, without having to actually perform the task followed by reinforcement. This can be modeled in the water maze through direct placement of a rat on the escape platform so that it can observe the location, and then assessing the subject's performance in swimming back to the platform. However, direct placement procedures have hardly been studied for two decades, reflecting a controversy about whether direct placement resulted in sufficiently rapid and direct swims back to the platform. In the present study, utilizing revised training methods, a more comprehensive measure of trajectory directness, a more rigorous sham-trained control procedure and an optimal placement-test interval, rats swam almost directly back to the platform in under 4s, significantly more quickly and directly than sham-trained subjects. Muscarinic cholinergic mechanisms, which are inactivated by scopolamine, are essential to memory for standard learning paradigms in the water maze. This experiment determined whether this would also be true for latent learning. ANOVA revealed significant negative effects of scopolamine on both speed and accuracy of trajectory, as well as significant positive effects of direct placement training vs. sham-training. In a probe trial, placement-trained animals without scopolamine spent significantly more time and path length in the target quadrant than trained rats with scopolamine and sham-trained rats without scopolamine. Scopolamine impairments are likely due to effects on memory, since the same dose had little effect on performance with a visible platform. The revised direct placement model offers a means of further comparing the neural mechanisms of latent learning with those of standard instrumental learning.

  20. Validation and scopolamine-reversal of latent learning in the water maze utilizing a revised direct platform placement procedure.

    PubMed

    Malin, David H; Schaar, Krystal L; Izygon, Jonathan J; Nghiem, Duyen M; Jabitta, Sikirat Y; Henceroth, Mallori M; Chang, Yu-Hsuan; Daggett, Jenny M; Ward, Christopher P

    2015-08-01

    The Morris water maze is routinely used to explore neurobiological mechanisms of working memory. Humans can often acquire working memory relevant to performing a task by mere sensory observation, without having to actually perform the task followed by reinforcement. This can be modeled in the water maze through direct placement of a rat on the escape platform so that it can observe the location, and then assessing the subject's performance in swimming back to the platform. However, direct placement procedures have hardly been studied for two decades, reflecting a controversy about whether direct placement resulted in sufficiently rapid and direct swims back to the platform. In the present study, utilizing revised training methods, a more comprehensive measure of trajectory directness, a more rigorous sham-trained control procedure and an optimal placement-test interval, rats swam almost directly back to the platform in under 4s, significantly more quickly and directly than sham-trained subjects. Muscarinic cholinergic mechanisms, which are inactivated by scopolamine, are essential to memory for standard learning paradigms in the water maze. This experiment determined whether this would also be true for latent learning. ANOVA revealed significant negative effects of scopolamine on both speed and accuracy of trajectory, as well as significant positive effects of direct placement training vs. sham-training. In a probe trial, placement-trained animals without scopolamine spent significantly more time and path length in the target quadrant than trained rats with scopolamine and sham-trained rats without scopolamine. Scopolamine impairments are likely due to effects on memory, since the same dose had little effect on performance with a visible platform. The revised direct placement model offers a means of further comparing the neural mechanisms of latent learning with those of standard instrumental learning. PMID:26033423

  1. Attitudes, personal evaluations, cognitive evaluation and interpersonal attraction: on the direct, indirect and reverse-causal effects.

    PubMed

    Singh, Ramadhar; Ho, Li Jen; Tan, Hui Lynn; Bell, Paul A

    2007-03-01

    The authors hypothesized that (1) attraction toward a stranger based on attitudinal similarity is automatic, but cognitive evaluation of the stranger's quality before the measurement of attraction can make attraction nonautomatic or controlled; (2) personal evaluations from the stranger activate automatic attraction and cognitive evaluation; (3) controlled attraction from attitudes and automatic attraction and cognitive evaluation from personal evaluations engender reverse-causal effects (i.e. they mediate each other); and (4) attraction and cognitive evaluation are distinct constructs. Attitudinal similarity between the participant and the stranger or personal evaluations of the former by the latter were varied in Experiment 1 (N=96), and were crossed with each other in Experiment 2 (N=240). Orders of response measurement were either cognitive evaluation followed by attraction or attraction followed by cognitive evaluation. Results confirmed the hypotheses. Implications of the findings are discussed. PMID:17355717

  2. Attitudes, personal evaluations, cognitive evaluation and interpersonal attraction: on the direct, indirect and reverse-causal effects.

    PubMed

    Singh, Ramadhar; Ho, Li Jen; Tan, Hui Lynn; Bell, Paul A

    2007-03-01

    The authors hypothesized that (1) attraction toward a stranger based on attitudinal similarity is automatic, but cognitive evaluation of the stranger's quality before the measurement of attraction can make attraction nonautomatic or controlled; (2) personal evaluations from the stranger activate automatic attraction and cognitive evaluation; (3) controlled attraction from attitudes and automatic attraction and cognitive evaluation from personal evaluations engender reverse-causal effects (i.e. they mediate each other); and (4) attraction and cognitive evaluation are distinct constructs. Attitudinal similarity between the participant and the stranger or personal evaluations of the former by the latter were varied in Experiment 1 (N=96), and were crossed with each other in Experiment 2 (N=240). Orders of response measurement were either cognitive evaluation followed by attraction or attraction followed by cognitive evaluation. Results confirmed the hypotheses. Implications of the findings are discussed.

  3. Micro-fabrication by laser radiation forces: a direct route to reversible free-standing three-dimensional structures.

    PubMed

    Athanasekos, Loukas; Vasileiadis, Miltiadis; Mantzaridis, Christos; Karoutsos, Vagelis C; Koutselas, Ioannis; Pispas, Stergios; Vainos, Nikolaos A

    2012-10-22

    The origins and first demonstration of structurally stable solids formed by use of radiation forces are presented. By experimentally proving that radiation forces can indeed produce stable solid material forms, a novel method enabling two- and three-dimensional (2d and 3d) microfabrication is introduced: An optical, non-contact single-step physical operation, reversible with respect to materials nature, based on the sole use of radiation forces. The present innovation is elucidated by the formation of polyisoprene and polybutadiene micro-solids, as well as plasmonic and fluorescent hybrids, respectively comprising Au nanoparticles and CdS quantum dots, together with novel concepts of polymeric fiber-drawing by radiation forces. PMID:23187237

  4. Utilization of the heat of catalytic combustion of low-calorie gaseous fuel mixtures by reversing the direction of their input

    SciTech Connect

    Boreskov, G.K.; Ivanov, A.G.; Matros, Y.S.

    1986-05-01

    In the recovery and processing of various industrial raw materials, gas-air mixtures are formed which contain small quantities of carbon monoxide, methane, and other combustible substances. This paper proposes and discusses a method of obtaining high-level heat from these low concentration gases. A nonsteady-state method is proposed in which the reaction mixture is fed at low temperature into a reactor and onto an initially warmed-up stationary catalyst bed; the direction of the feed is periodically reversed. This process forms a slowly migrating front of an exothermic chemical reaction in the bed.

  5. First simultaneous measurements of waves generated at the bow shock in the solar wind, the magnetosphere and on the ground

    NASA Astrophysics Data System (ADS)

    Clausen, L. B. N.; Yeoman, T. K.; Fear, R. C.; Behlke, R.; Lucek, E. A.; Engebretson, M. J.

    2009-01-01

    On 5 September 2002 the Geotail satellite observed the cone angle of the Interplanetary Magnetic Field (IMF) change to values below 30° during a 56 min interval between 18:14 and 19:10 UT. This triggered the generation of upstream waves at the bow shock, 13 RE downstream of the position of Geotail. Upstream generated waves were subsequently observed by Geotail between 18:30 and 18:48 UT, during times the IMF cone angle dropped below values of 10°. At 18:24 UT all four Cluster satellites simultaneously observed a sudden increase in wave power in all three magnetic field components, independent of their position in the dayside magnetosphere. We show that the 10 min delay between the change in IMF direction as observed by Geotail and the increase in wave power observed by Cluster is consistent with the propagation of the IMF change from the Geotail position to the bow shock and the propagation of the generated waves through the bow shock, magnetosheath and magnetosphere towards the position of the Cluster satellites. We go on to show that the wave power recorded by the Cluster satellites in the component containing the poloidal and compressional pulsations was broadband and unstructured; the power in the component containing toroidal oscillations was structured and shows the existence of multi-harmonic Alfvénic continuum waves on field lines. Model predictions of these frequencies fit well with the observations. An increase in wave power associated with the change in IMF direction was also registered by ground based magnetometers which were magnetically conjunct with the Cluster satellites during the event. To the best of our knowledge we present the first simultaneous observations of waves created by backstreaming ions at the bow shock in the solar wind, the dayside magnetosphere and on the ground.

  6. The cometary H II regions of DR 21: Bow shocks or champagne flows or both?

    NASA Astrophysics Data System (ADS)

    Immer, K.; Cyganowski, C.; Reid, M. J.; Menten, K. M.

    2014-03-01

    We present deep Very Large Array H66α radio recombination line (RRL) observations of the two cometary H II regions in DR 21. With these sensitive data, we test the "hybrid" bow shock/champagne flow model previously proposed for the DR 21 H II regions. The ionized gas down the tail of the southern H II region is redshifted by up to ~30 km s-1 with respect to the ambient molecular gas, as expected in the hybrid scenario. The RRL velocity structure, however, reveals the presence of two velocity components in both the northern and southern H II regions. This suggests that the ionized gas is flowing along cone-like shells, swept-up by stellar winds. The observed velocity structure of the well-resolved southern H II region is most consistent with a picture that combines a stellar wind with stellar motion (as in bow shock models) along a density gradient (as in champagne flow models). The direction of the implied density gradient is consistent with that suggested by maps of dust continuum and molecular line emission in the DR 21 region. The image cubes are only available as a FITS file at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/563/A39Table 2, Fig. 4, and Appendices A and B are available in electronic form at http://www.aanda.org

  7. Cometary compact H II regions are stellar-wind bow shocks

    NASA Technical Reports Server (NTRS)

    Van Buren, Dave; Mac Low, Mordecai-Mark; Wood, Douglas O. S.; Churchwell, ED

    1990-01-01

    Comet-shaped H II regions, like G34.3 + 0.2, are easily explained as bow shocks created by wind-blowing massive stars moving supersonically through molecular clouds. The required velocities of the stars through dense clumps are less than about 10 km/s, comparable to the velocity dispersion of stars in OB associations. An analytic model of bow shocks matches the gross characteristics seen in the radio continuum and the velocity structure inferred from hydrogen recombination and molecular line observations. The champagne flow model cannot account for these structures. VLBI observations of masers associated with the shells of cometary compact H II regions should reveal tailward proper motions predominantly parallel to the shell, rather than perpendicular. It is predicted that over a decade baseline, high signal-to-noise VLA observations of this class of objects will show headward pattern motion in the direction of the symmetry axis, but not expansion. Finally, shock-generated and coronal infrared lines are also predicted.

  8. Technical Note: Measurement of bow tie profiles in CT scanners using radiochromic film

    SciTech Connect

    Whiting, Bruce R.; Dohatcu, Andreea C.; Evans, Joshua D.; Williamson, Jeffrey F.; Politte, David G.

    2015-06-15

    Purpose: To provide a noninvasive technique to measure the intensity profile of the fan beam in a computed tomography (CT) scanner that is cost effective and easily implemented without the need to access proprietary scanner information or service modes. Methods: The fabrication of an inexpensive aperture is described, which is used to expose radiochromic film in a rotating CT gantry. A series of exposures is made, each of which is digitized on a personal computer document scanner, and the resulting data set is analyzed to produce a self-consistent calibration of relative radiation exposure. The bow tie profiles were analyzed to determine the precision of the process and were compared to two other measurement techniques, direct measurements from CT gantry detectors and a dynamic dosimeter. Results: The radiochromic film method presented here can measure radiation exposures with a precision of ∼6% root-mean-square relative error. The intensity profiles have a maximum 25% root-mean-square relative error compared with existing techniques. Conclusions: The proposed radiochromic film method for measuring bow tie profiles is an inexpensive (∼$100 USD + film costs), noninvasive method to measure the fan beam intensity profile in CT scanners.

  9. Origin of the Large Bandgap Bowing in Highly Mismatched Semiconductor Alloys

    NASA Technical Reports Server (NTRS)

    Wu, J.; Walukiewicz, W.; Yu, K. M.; Ager, J. W., III; Haller, E. E.; Miotkowski, I.; Ramdas, A. K.; Su, Ching-Hua; Sou, I. K.; Perera, R.; Curreri, Peter A. (Technical Monitor)

    2002-01-01

    We use a combination of optical and soft x-ray fluorescence techniques to investigate the composition dependence of the band edge energies in ZnSe(1-x)Te(x) and ZnS(1-x)Te(x) alloys. The results reveal entirely different origins of the large bandgap bowing for alloys with small and large Te content. On the Te-rich side, the reduction of the bandgap is well explained by the band anticrossing interaction between the Se or S localized states and the ZnTe conduction band states. On the Se or S-rich side, an interaction between the localized Te states and the degenerate GAMMA valence bands of ZnSe or ZnS is responsible for the bandgap reduction and the rapid increase of the spin-orbit splitting with increasing Te concentration. Results of soft x-ray fluorescence experiments provide direct evidence for the valence band anticrossing interaction. The bandgap bowing over the entire composition range is accounted for by a linear interpolation between the conduction band anticrossing and valence band anticrossing models.

  10. The excitation conditions of magnetospheric convection by the electric current generated in the bow shock

    NASA Astrophysics Data System (ADS)

    Sedykh, P. A.; Ponomarev, E. A.

    The solar wind undergoes the greatest change of its parameters during the passage through the bow shock front Its density in this case increases by the factor of four and gas and magnetic pressure increase more than by an order of magnitude In this paper we re-examine the consequences of the fact of electric current generation at the bow shock front that we considered at an earlier date and the dependence of the direction of this current on the sign of IMF Bz-component The first consequence is the closure of the aforementioned current through the magnetosphere It was found that this process is a two-stage one Initially the electric field penetrates and establishes in the medium a new convective regime After that depending on the degree of flow inhomogeneity a plasma density distribution can be established which corresponds to the electric current equal to the external current The new steady state to which the new convection velocity field and the new plasma pressure field correspond is established within the time of the order of the transit time taken by the magnetosonic wave to propagate through the entire system Also a linkage between the power dissipated inside the magnetosphere and the parameters of plasma convection existing therein is shown

  11. Energy band bowing parameter in MgZnO alloys

    SciTech Connect

    Wang, Xu; Saito, Katsuhiko; Tanaka, Tooru; Nishio, Mitsuhiro; Guo, Qixin; Nagaoka, Takashi; Arita, Makoto

    2015-07-13

    We report on bandgap bowing parameters for wurtzite and cubic MgZnO alloys from a study of high quality and single phase films in all Mg content range. The Mg contents in the MgZnO films were accurately determined using the energy dispersive spectrometer and X-ray photoelectron spectroscopy (XPS). The measurement of bandgap energies by examining the onset of inelastic energy loss in core-level atomic spectra from XPS is proved to be valid for determining the bandgap of MgZnO films. The dependence of the energy bandgap on Mg content is found to deviate downwards from linearity. Fitting of the bandgap data resulted in two bowing parameters of 2.01 ± 0.04 eV and 1.48 ± 0.11 eV corresponding to wurtzite and cubic MgZnO films, respectively.

  12. Face bow and articulator for planning orthognathic surgery: 2 articulator.

    PubMed

    Walker, Fraser; Ayoub, Ashraf F; Moos, Khursheed F; Barbenel, Joseph

    2008-10-01

    Patients who require orthognathic surgery may have asymmetry of the position of the temporomandibular joints relative to the maxilla, which is impossible to reproduce on the current semiadjustable articulators used for surgical planning. We describe a highly-adjustable spirit level orthognathic face bow that allows records to be made of patients with asymmetrical maxillae. The orthognathic articulator also allows the position of the condylar components of the articulator to be adjusted in three dimensions. The use of the new face bow and articulator made it possible to mount the dental casts of asymmetrical faces to reproduce their clinical appearance. The devices were evaluated by comparing the measurements of anatomical variables obtained from cephalometric radiographs with equivalent values obtained from the orthognathic articulator and casts mounted on the articulator. Although the measurements showed significant intersubject variability, the angle between the horizontal and maxillary occlusal plane, occlusal cant angle, and intercondylar widths, were not significantly different.

  13. MESSENGER Observations of Mercury's Bow Shock and Magnetopause

    NASA Technical Reports Server (NTRS)

    Slavin, James A.; Boardsen, S. A.; Sarantos, M.; Acuna, M. H.; Anderson, B. J.; Baker, D. N.; Benna, M.; Gloeckler, G.; Gold, R. E.; Ho, G. C.; Korth, H.; Krimigis, S. M.; Livi, S. A.; McNutt, R. L., Jr.; Raines, J. M.; Schriver, D.; Solomon, S. C.; Travnicek, P.; Zurbuchen, T. H.

    2008-01-01

    MESSENGER'S 14 January 2008 encounter with Mercury will provide the first new observations of the solar wind interaction with this planet since the Mariner 10 flybys that took place over 30 years ago. The closest approach distance for this first MESSENGER flyby is targeted for an altitude of 200 km as compared with the 707 km and 327 km attained by Mariner 10 on 29 March 1974 and 16 March 1975, respectively. The locations of the bow shock and magnetopause boundaries observed by MESSENGER will be examined and compared against those found in the earlier Mariner 10 measurements and the predictions of theoretical models and numerical simulations. The structure of the magnetopause will be investigated for the presence of flux transfer events or other evidence of magnetic reconnection as will the more general implications of these new MESSENGER bow shock and magnetopause observations for the global solar wind interaction with Mercury.

  14. Magnetohydrodynamic and gasdynamic theories for planetary bow waves

    NASA Technical Reports Server (NTRS)

    Spreiter, J. R.; Stahara, S. S.

    1983-01-01

    A bow wave was previously observed in the solar wind upstream of each of the first six planets. The observed properties of these bow waves and the associated plasma flows are outlined, and those features identified that can be described by a continuum magnetohydrodynamic flow theory. An account of the fundamental concepts and current status of the magnetohydrodynamic and gas dynamic theories for solar wind flow past planetary bodies is provided. This includes a critical examination of: (1) the fundamental assumptions of the theories; (2) the various simplifying approximations introduced to obtain tractable mathematical problems; (3) the limitations they impose on the results; and (4) the relationship between the results of the simpler gas dynamic-frozen field theory and the more accurate but less completely worked out magnetohydrodynamic theory. Representative results of the various theories are presented and compared.

  15. Directional reversals enable Myxococcus xanthus cells to produce collective one-dimensional streams during fruiting-body formation

    PubMed Central

    Thutupalli, Shashi; Sun, Mingzhai; Bunyak, Filiz; Palaniappan, Kannappan; Shaevitz, Joshua W.

    2015-01-01

    The formation of a collectively moving group benefits individuals within a population in a variety of ways. The surface-dwelling bacterium Myxococcus xanthus forms dynamic collective groups both to feed on prey and to aggregate during times of starvation. The latter behaviour, termed fruiting-body formation, involves a complex, coordinated series of density changes that ultimately lead to three-dimensional aggregates comprising hundreds of thousands of cells and spores. How a loose, two-dimensional sheet of motile cells produces a fixed aggregate has remained a mystery as current models of aggregation are either inconsistent with experimental data or ultimately predict unstable structures that do not remain fixed in space. Here, we use high-resolution microscopy and computer vision software to spatio-temporally track the motion of thousands of individuals during the initial stages of fruiting-body formation. We find that cells undergo a phase transition from exploratory flocking, in which unstable cell groups move rapidly and coherently over long distances, to a reversal-mediated localization into one-dimensional growing streams that are inherently stable in space. These observations identify a new phase of active collective behaviour and answer a long-standing open question in Myxococcus development by describing how motile cell groups can remain statistically fixed in a spatial location. PMID:26246416

  16. Collision-induced photon echo at the transition 0{r_reversible}1 in ytterbium vapor: Direct proof of depolarizing collision anisotropy

    SciTech Connect

    Rubtsova, N. N.; Gol'dort, V. G.; Ishchenko, V. N.; Khvorostov, E. B.; Kochubei, S. A.; Reshetov, V. A.; Yevseyev, I. V.

    2011-09-15

    A collision-induced photon echo arising at the transition 0{r_reversible}1 of ytterbium in the presence of heavy atomic buffer is investigated. Collision-induced echo signal appears in the case of mutually orthogonal linear polarizations of exciting pulses and it is absent without buffer. Collision-induced echo power grows with buffer pressure up to the maximum value and decays exponentially at further buffer pressure growth. Collision-induced echo power is essentially less than that of the ordinary echo generated by pulses with parallel polarizations in the same mixture, and its polarization is linear with the polarization vector directed along that of the first exciting pulse. All the properties of collision-induced photon echo are explained on the basis of collision relaxation dependence on the direction of active atom velocity.

  17. Optimization of UV-LED curable printing material for applications in direct writing systems: Inkjet, reverse offset, and micro dispensing GPD

    NASA Astrophysics Data System (ADS)

    Varela, Ada Judith Ortega

    The quality of a product fabricated by direct writing methods will depend greatly on the properties of the printing material and its compatibility with the printing process. Although multiple advances in developing printing inks and pastes with novel properties are being made, the potential those can bring to electronics is hindered by their stability and performance during the printing process. In this study a UV-LED curable acrylic material was used to test the optimization of inks and pastes for three of the most common direct writing systems: Piezo-type Inkjet, Reverse Offset Roll to Plate, and Micro Deposition. The viscosity of the photosensitive acrylic matrix was controlled by either the addition of diluents or electronically functional reinforcement material. The contact angle of the optimized solutions on 16 different Polyester, Polyimide, and Paper films was observed. Solutions with larger contact angles showed better line definition for the Inkjet and the Micro Dispense systems. In addition to the contact angle differential, the rheological properties showed to be a determinant factor for the feasibility of a solution to undergo the reverse offset printing process. The UV curable acrylic demonstrated electrical conductivity when 2% (wt.) MWCNT were ultrasonically mixed in the matrix and then cured with a 385nm wavelength for 3 seconds. Only the micro deposition system was capable of printing the acrylic-MWCNT paste and the relationship between the contact angle, pattern accuracy, substrate selection, and electrical conductivity, was determined.

  18. Bow-corridor local integrated resource plan: Draft plan

    SciTech Connect

    Not Available

    1990-01-01

    This plan presents the Government of Alberta's resource management policy for public lands and resources within the Bow Corridor. Resource potentials and opportunities for development are identified to assist in the economic progress of the province. The plan includes identification of its purpose and scope and the context in which it is presented; and resource management objectives and guidelines for ecological and aesthetic resources, fisheries, forests, historical resources, minerals, range land, settlement, tourism/recreation, water and watersheds and wildlife.

  19. Bow shocks and magnetotails of Venus and Mars - A comparison

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Ong, M.; Luhmann, J. G.; Schwingenschuh, K.; Riedler, W.; Eroshenko, E.

    1992-01-01

    Observations of the bow shock location and the structure of the magnetotail of Mars by the Phobos spacecraft and of Venus by the Pioneer Venus Orbiter reveal the solar wind interactions with these two planets to be quite similar. The subsolar bow shocks of both Venus and Mars lie at 1.47 planetary radii while at the terminator they are at 2.40 and 2.65 planetary radii, respectively. Both bow shocks have oval cross sections when viewed from the sun whose major axes are controlled by the orientation of the interplanetary magnetic field. The tail lobes of both planets are similarly controlled by the IMF orientation. The strength of the solar/antisolar component of the magnetic field is 17 nT at Venus and 14 nT at Mars. The component perpendicular to the tail axis is about 1/2 the corresponding IMF component at Venus and 2 times this component at Mars. However, when these measurements are compared in terms of the distance down the tail at which each were taken, the data from the two planets are quite consistent. Hence both Venus and Mars have principally induced magnetospheres and magnetotails which stand off the solar wind flow.

  20. High-frequency electrostatic waves near earth's bow shock

    NASA Technical Reports Server (NTRS)

    Onsager, T. G.; Holzworth, R. H.; Koons, H. C.; Bauer, O. H.; Gurnett, D. A.

    1989-01-01

    Electrostatic wave measurements from the Active Magnetospheric Particle Tracer Explorer Ion Release Module have been used to investigate the wave modes and their possible generation mechanisms in the earth's bow shock and magnetosheath. It is demonstrated that electrostatic waves are present in the bow shock and magnetosheath with frequencies above the maximum frequency for Doppler-shifted ion acoustic waves, yet below the plasma frequency. Waves in this frequency range are tentatively identified as electron beam mode waves. Data from 45 bow shock crossings are then used to investigate possible correlations between the electrostatic wave properties and the near-shock plasma parameters. The most significant relationships found are anticorrelations with Alfven Mach number and electron beta. Mechanisms which might produce electron beams in the shock and magnetosheath are discussed in terms of the correlation study results. These mechanisms include acceleration by the cross-shock electric field and by lower hybrid frequency waves. A magnetosheath 'time of flight' mechanism, in analogy to the electron foreshock region, is introduced as another possible beam generation mechanism.

  1. Polarization of circumstellar bow shocks due to electron scattering

    NASA Astrophysics Data System (ADS)

    Shrestha, Manisha; Hoffman, J. L.; Neilson, H.; Ignace, R.

    2014-01-01

    Circumstellar material (CSM) provides a link between interacting supernovae and their massive progenitor stars. This CSM arises from stellar winds, outflows, or eruptions from a massive star before it explodes and can be detected around stars or supernovae with polarimetric observations. We use a Monte Carlo based radiative transfer code (SLIP) to investigate the polarization created by different models for the CSM surrounding a central source such as supernovae or massive stars. We vary parameters such as the shape, optical depth, temperature, and brightness of the CSM and compare the simulated flux and polarization behavior with observational data. We present results from new simulations that assume a bow shock shape for the CSM. Bow shocks are commonly observed around massive stars; this shape forms when a star moving more quickly than the speed of sound in the local interstellar medium emits a stellar wind that drives a shock wave into the ISM. Since a bow shock projects an aspherical shape onto the sky, light from the central source that scatters in the shock region becomes polarized. We present electron-scattering polarization maps for this geometry and discuss the behavior of observed polarization with viewing angle in the unresolved case.

  2. Global hybrid simulations: foreshock and bow shock morphology

    NASA Astrophysics Data System (ADS)

    Blanco-Cano, Xochitl; Omidi, Nojan; Russell, Christopher

    The solar wind interaction with earth's magnetosphere is mediated by the formation of a bow shock. Ahead of this shock a foreshock forms. Global hybrid simulations have proven to be very useful to study these complex regions, where kinetic effects play a major role in dissipation process and largely affect the large scale dynamics of the foreshock-bow shock-magnetosheath system. In this work we use global hybrid simulations to study solar wind coupling with the magnetosphere for oblique (45° ) and radial IMF geometries. We find that the foreshock morphology changes drastically from one case to the other. We study ULF waves' properties, evolution, and their impact on the quasi-parallel shock. We also investigate differences in suprathermal ion distributions under the two geometries and relate this to wave origin. We find that under the radial geometry the foreshock is permeated also by density cavities that are not clear for the oblique interaction. We discuss the properties of these cavities and their impact on the quasi-parallel bow shock. We also relate simulation cavities to observations in earth's foreshock.

  3. Bow hunter's syndrome secondary to bilateral dynamic vertebral artery compression.

    PubMed

    Healy, Andrew T; Lee, Bryan S; Walsh, Kevin; Bain, Mark D; Krishnaney, Ajit A

    2015-01-01

    Bow hunter's syndrome is a condition in which vertebrobasilar insufficiency is resultant from head rotation, clinically manifested by presyncopal sensation, syncope, dizziness, and nausea. It is usually diagnosed clinically, with supporting vascular imaging demonstrating an occluded or at the very least compromised unilateral vertebral artery, while the dominant vertebral artery remains patent in the neutral position. Dynamic imaging is utilized to confirm the rotational compression of the dominant vertebral artery. We present the rare case of a patient with typical Bow hunter's symptoms, bilaterally patent vertebral arteries on neutral imaging, and bilateral compromise with head rotation. Our patient underwent posterior decompression of the culprit atlanto-axial transverse foramen and subaxial cervical fusion, with resolution of his symptoms. Our patient exemplifies the possibility of bilateral dynamic vertebral artery occlusion. We show that Bow hunter's syndrome cannot be ruled out in the setting of bilaterally patent vertebral arteries on neutral imaging and that severe cervical spondylosis should impart further clinical suspicion of this unusual phenomenon. PMID:25070633

  4. Method for measuring violin sound radiation based on bowed glissandi and its application to sound synthesis.

    PubMed

    Perez Carrillo, Alfonso; Bonada, Jordi; Patynen, Jukka; Valimaki, Vesa

    2011-08-01

    This work presents a method for measuring and computing violin-body directional frequency responses, which are used for violin sound synthesis. The approach is based on a frame-weighted deconvolution of excitation and response signals. The excitation, consisting of bowed glissandi, is measured with piezoelectric transducers built into the bridge. Radiation responses are recorded in an anechoic chamber with multiple microphones placed at different angles around the violin. The proposed deconvolution algorithm computes impulse responses that, when convolved with any source signal (captured with the same transducer), produce a highly realistic violin sound very similar to that of a microphone recording. The use of motion sensors allows for tracking violin movements. Combining this information with the directional responses and using a dynamic convolution algorithm, helps to improve the listening experience by incorporating the violinist motion effect in stereo. PMID:21877814

  5. Method for measuring violin sound radiation based on bowed glissandi and its application to sound synthesis.

    PubMed

    Perez Carrillo, Alfonso; Bonada, Jordi; Patynen, Jukka; Valimaki, Vesa

    2011-08-01

    This work presents a method for measuring and computing violin-body directional frequency responses, which are used for violin sound synthesis. The approach is based on a frame-weighted deconvolution of excitation and response signals. The excitation, consisting of bowed glissandi, is measured with piezoelectric transducers built into the bridge. Radiation responses are recorded in an anechoic chamber with multiple microphones placed at different angles around the violin. The proposed deconvolution algorithm computes impulse responses that, when convolved with any source signal (captured with the same transducer), produce a highly realistic violin sound very similar to that of a microphone recording. The use of motion sensors allows for tracking violin movements. Combining this information with the directional responses and using a dynamic convolution algorithm, helps to improve the listening experience by incorporating the violinist motion effect in stereo.

  6. Quantitative analysis of RNA cleavage during RNA-directed DNA synthesis by human immunodeficiency and avian myeloblastosis virus reverse transcriptases.

    PubMed Central

    DeStefano, J J; Mallaber, L M; Fay, P J; Bambara, R A

    1994-01-01

    We have determined the extent of RNA cleavage carried out during DNA synthesis by either human immunodeficiency virus (HIV) or avian myeloblastosis virus (AMV) reverse transcriptases (RTs). Conditions were chosen that allowed the analysis of the cleavage and synthesis performed by the RT during one binding event on a given template-primer. The maximum quantity of ribonuclease H (RNase H) sensitive template RNA left after synthesis by the RTs was determined by treatment with Escherichia coli RNase H. RNA cleavage products that were expected to be too short to remain hybridized, less than 13 nucleotides in length, were quantitated. Results showed that HIV- and AMV-RT degraded about 80% and less than 20%, respectively, of the potentially degradable RNA to these short products. Survival of longer, hybridized RNA was not a result of synthesis by a population of RTs that had selectively lost RNase H activity. Using an assay that evaluated the proportion of primers extended versus RNA templates cleaved during primer-extension by the RTs, we determined that essentially each molecule of HIV- and AMV-RT with polymerase also has RNase H activity. The results indicate that although both HIV- and AMV-RTs cleave the RNA template during synthesis, the number of cleavages per nucleotide addition with HIV-RT is much greater. They also suggest that some hybridized RNA segments remain right after the passage of the RT making the first DNA strand. In vivo, these segments would have to be cleaved or displaced in later reactions before second strand DNA synthesis could be completed. Images PMID:7524028

  7. Investigation on Ring/Split-Ring Loaded Bow-Tie Antenna for Compactness and Notched-Band

    NASA Astrophysics Data System (ADS)

    Peng, Lin; Xie, Ji-yang; Jiang, Xing; Li, Si-min

    2016-03-01

    In this paper, a Bow-tie antenna with size reduction, impedance matching and radiation pattern improvement characteristics is designed with an encircling ring. Moreover, further size reduction is achieved by utilizing two symmetric split rings with more frequency tuning flexibility. Research found the ring loaded Bow-tie antenna (RLBA) shows better performance than the referenced Bow-tie antenna (RBA), and the mechanisms of performance improvements are also investigated and found to be the loading ring acts as two symmetric dipoles in the direction of the antenna's polarization. Then, using two symmetric split rings on the opposite side of the substrate as replacement of the encircling ring will prolong the length of the dipoles, and achieves further size reduction. The antenna is denoted as dual split ring loaded Bow-tie antenna (DSRBA). The low cutoff frequencies of RBA, RLBA and DSRBA with identical antenna size are 2.65 GHz, 2.27 GHz and 2.06 GHz, respectively. Then, the corresponding diameters of the antennas are 0.353 λc, 0.303 λc, and 0.275 λc, where λc are their corresponding wavelength of the lower cutoff frequencies. Furthermore, a notched-band is generated as a byproduct of the split rings, and it is owing to the new resonance of the overlap areas of the split rings. The notch can be used to alleviate interference of WiMAX band by carefully choosing the split rings' size. Radiation patterns of RLBA and DSRBA are also improved as current distributions of the high frequencies are trained in order by the ring/split-rings. Measurements are performed to verify the designs.

  8. New Observations of Solar Wind Interaction with Earth's Bow Shock

    NASA Astrophysics Data System (ADS)

    Parks, George; Lee, Ensang; Yang, Zhongwei; Liu, Ying; Fu, Suiyan; Dandouras, Iannis; Reme, Henri; Canu, Patrick; Goldstein, Melvyn

    2016-04-01

    The mass, charge and energy dependence of the SW interaction with the bow shock was studied from early days of HEOS-1 and ISEE (Formisano et al, 1970; Peterson et al., 1979). These observations have shown that while thermalization of H+ occurs across the boundary, sometimes the SW He++ ions are found with unchanged energy spectra downstream of the shock inside the magnetosheath and that both SW H+ and He++ beams could be found in the downstream magnetosheath with the same bulk velocities. These studies however used He++ data accumulated over 30 minutes and since the SW dynamics include much faster time variations the results are likely affected by spatial and temporal variations. Moreover, it was not known at that time that the plasma in the neighborhood of the bow shock often include the reflected, gyrating and particles leaking out of the magnetosheath (Skopke et al., 1982; Thomsen et al., 1985) and since these particles occupy different parts of the velocity space, they can significantly affect the SW velocity and temperature computed from first and second velocity moments. To alleviate these problems, a microprocessor-controlled SW plasma experiment was designed and flown on Cluster that selects only particles near the peak energy of the SW distribution, thereby minimizing contamination from the other particles (Rème et al., 2001). We have studied ~110 shock crossings upstream and downstream of the quasi-perpendicular and quasi-parallel bow shock regions and find that in 44 cases the SW beams crossed the shock retaining much of their upstream features. On average the temperature of upstream SW H+ ions was ~4 eV and in the magnetosheath ~4.2 eV, indicating there was little or no heating of the SW going across the bow. The He++ ions have temperatures typically 4 times that of H+ ions in the SW a value consistent with equipartition of energy. Unlike H+ ions, He++ ions very often do not slow down going across the shock. These observations indicate that the SW

  9. Similarities and Differences between the Termination Foreshock/ Bow Shock and Planetary Bow Shocks

    NASA Astrophysics Data System (ADS)

    Krimigis, S. M.; Decker, R. B.; Roelof, E. C.; Hill, M. E.

    2006-05-01

    It is now evident that Voyager 1 (V1) entered the termination foreshock (TFS) at ~~85 AU in mid-2002, exited this region in early 2003 and re-entered in the late 2003-early 2004 time frame, before finally crossing the termination shock (TS) at ~~94 AU on December 16, 2004. The TFS region is characterized by large intensities of tangentially outward-moving beams of energetic ions E > 40 keV, and generally isotropic electron intensity increases E > 350 keV (Krimigis et al, 2003; Decker et al, 2005). Elevated magnetic field intensities were observed throughout these periods (Burlaga et al, 2003, 2005) and comparison with particle pressures showed this region to be a high-beta plasma (Krimigis et al, 2004, 2005). Proximity of the TS was also evident from occasional electron plasma oscillations seen as early as 91 AU (Gurnett and Kurth, 2005). In this paper we examine the extent to which the TFS and TS exhibit properties seen in planetary bow shocks using data from Voyager?s flyby of the outer planets and Cassini data in the vicinity of Saturn. Magnetic field distributions in these high-beta regions appear to be Gaussian. A possible source for the TSF particles is the supertherma1 population residing in the heliosheath, similar to upstream ions observed leaking from planetary magnetospheres. Krimigis, S.M. et al, Nature, 426, pg 45-48, 2003. Decker, R. B. et al, Science, 309, 2020- 2024, 2005. Burlaga et al, Geophys. Res. Lett., 30, NO. 20, 2072, doi:10.1029/2003GL018291, 2003. Burlaga, L. F, et al, Science, 309, 2027-2029, 2005 Krimigis S. M., et al, V. Florinski, N. V. Pogorelov, and G. P. Zank (eds) CP719, American Institute of Physics, 0-7354-0199-3/04, 133-138, 2004. Krimigis, S. M., et al, Proceedings of the Solar Wind 11 / SOHO 16 Conference,12-17 June 2005, Whistler, Canada, , B. Fleck & T.H. Zurbuchen (eds), (ESA SP-592, September 2005) Gurnett, D. A., and W. S. Kurth, Science, 309, 2025- 2027, 2005

  10. Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airflow obstruction.

    PubMed Central

    Melchor, R; Biddiscombe, M F; Mak, V H; Short, M D; Spiro, S G

    1993-01-01

    BACKGROUND--Earlier studies of aerosol deposition in the lungs have relied on indirect labelling of Teflon spheres of a similar size distribution to the drug in question and have assumed similar aerodynamic properties. Using a modification of a new technique for directly labelling salbutamol, the deposition of salbutamol within the lungs of normal subjects and patients with asthma has been studied with the use of a metered dose inhaler (MDI) alone, an MDI with a spacer device, and a dry powder inhaler (DPI). METHOD--Salbutamol was directly labelled with technetium-99m and placed in an MDI or DPI. Ten normal subjects and 19 patients with asthma inhaled 200 micrograms of salbutamol by means of the MDI alone, the MDI with a spacer device attached, and by DPI on separate days. Deposition was assessed by a dual headed gamma camera after inhalation of the drug. RESULTS--The total mean (SD) percentage deposition of the drug in the normal subjects was 21.6% (8.9%) with the MDI alone, 20.9% (7.8%) with the MDI with spacer, and 12.4% (3.5%) with the DPI. For the patients, the mean percentage deposition was 18.2% (7.8%) with the MDI alone, 19.0% (8.9%) with the MDI and spacer, and 11.4% (5.0%) with the DPI. Bronchodilatation achieved by the patients was similar with all three techniques. Mean peripheral lung deposition was significantly greater with a spacer device than when the MDI was used alone in both normal subjects (49.4% (6.1%) v 44.1% (9.9%)) and patients (38.6% (11.1%) v 30.4% (9.4%)). CONCLUSIONS--The deposition of directly labelled salbutamol from an MDI is greater than previously estimated by indirect labelling techniques. The deposition of labelled salbutamol from a DPI, however, is little different from that measured by indirect techniques. PMID:8322237

  11. Dependence of sound characteristics on the bowing position in a violin

    NASA Astrophysics Data System (ADS)

    Roh, YuJi; Kim, Young H.

    2014-12-01

    A quantitative analysis of violin sounds produced for different bowing positions over the full length of a violin string has been carried out. An automated bowing machine was employed in order to keep the bowing parameters constant. A 3-dimensional profile of the frequency spectrum was introduced in order to characterize the violin's sound. We found that the fundamental frequency did not change for different bowing positions, whereas the frequencies of the higher harmonics were different. Bowing the string at 30 mm from the bridge produced musical sounds. The middle of the string was confirmed to be a dead zone, as reported in previous works. In addition, the quarter position was also found to be a dead zone. Bowing the string 90 mm from the bridge dominantly produces a fundamental frequency of 864 Hz and its harmonics.

  12. Quantum Operation Time Reversal

    SciTech Connect

    Crooks, Gavin E.

    2008-03-25

    The dynamics of an open quantum system can be described by a quantum operation: A linear, complete positive map of operators. Here, I exhibit a compact expression for the time reversal of a quantum operation, which is closely analogous to the time reversal of a classical Markov transition matrix. Since open quantum dynamics are stochastic, and not, in general, deterministic, the time reversal is not, in general, an inversion of the dynamics. Rather, the system relaxes toward equilibrium in both the forward and reverse time directions. The probability of a quantum trajectory and the conjugate, time reversed trajectory are related by the heat exchanged with the environment.

  13. Congenital anterolateral bowing of the tibia with ipsilateral polydactyly of the great toe.

    PubMed

    Kitoh, H; Nogami, H; Hattori, T

    1997-12-31

    We report on two cases of congenital unilateral anterolateral bowing and focal defect of the tibia associated with ipsilateral polydactyly of the great toe. Computed tomographic examination showed an unusual partial cleft of the tibia at the site of bowing. A long follow-up of one patient showed spontaneous resolution of the bowing without progression to pseudoarthrosis. These anomalies should be considered as a new entity related to the tibial developmental field. PMID:9415465

  14. Direct experimental evidence for the reversal of carrier type upon hydrogen intercalation in epitaxial graphene/SiC(0001)

    SciTech Connect

    Rajput, S. Li, Y. Y.; Li, L.

    2014-01-27

    Raman spectroscopy and scanning tunneling microscopy/spectroscopy measurements are performed to determine the atomic structure and electronic properties of H-intercalated graphene/SiC(0001) obtained by annealing the as-grown epitaxial graphene in hydrogen atmosphere. While the as-grown graphene is found to be n-type with the Dirac point (E{sub D}) at 450 and 350 meV below Fermi level for the 1st and 2nd layer, the H-intercalated graphene is p-type with E{sub D} at 320 and 200 meV above. In addition, ripples are observed in the now quasi-free standing graphene decoupled from the SiC substrate. This causes fluctuations in the Dirac point that directly follow the undulations of the ripples, resulting in electron and hole puddles in the H-intercalated graphene/SiC(0001)

  15. Asymmetries in the location of the Venus and Mars bow shock

    NASA Technical Reports Server (NTRS)

    Zhang, T.-L.; Schwingenschuh, K.; Russell, C. T.; Luhmann, J. G.

    1991-01-01

    An examination of observations of the position of the terminator bow shock at Venus and Mars shows that the terminator bow shock varies with the angle between the local bow shock normal and the upstream magnetic field. The part of the shock on the quasi-parallel side is closer to the planet than the part on the quasi-perpendicular side, a result which had been suggested by an earlier computer simulation by Thomas and Winske (1990). This bow shock asymmetry is observed to be larger at Mars than at Venus.

  16. Asymmetries in the location of the Venus and Mars bow shock

    NASA Astrophysics Data System (ADS)

    Zhang, T.-L.; Schwingenschuh, K.; Russell, C. T.; Luhmann, J. G.

    1991-02-01

    An examination of observations of the position of the terminator bow shock at Venus and Mars shows that the terminator bow shock varies with the angle between the local bow shock normal and the upstream magnetic field. The part of the shock on the quasi-parallel side is closer to the planet than the part on the quasi-perpendicular side, a result which had been suggested by an earlier computer simulation by Thomas and Winske (1990). This bow shock asymmetry is observed to be larger at Mars than at Venus.

  17. [Subjective impressions of bowing actions and their appropriateness in specific social contexts].

    PubMed

    Shibata, Hiroshi; Takahashi, Junichi; Gyoba, Jiro

    2015-02-01

    The current study used video clips of bowing actions depicted by three-dimensional computer graphics. The bend angle (15 degrees and 45 degrees) and duration of the bent posture (0-4.5 seconds) were varied. In the first experiment, the participants rated their subjective impressions of the bowing actions. The bowing actions that were made at a 45 degrees angle and held for more than 1 second were rated as courteous. Bowing motions held for shorter durations were rated as smooth. In the second experiment, the participants evaluated whether a bowing action was appropriate for a specific social context. The participants judged 15 degrees-angle bowing of no/ very short duration appropriate for greeting, 45 degrees-angle bowing of no / short duration appropriate for gratitude, and 45 degrees-angle bowing for about 2 seconds appropriate for an apology. The results of these two experiments are discussed in terms of how angle and duration influence the impressions and evaluations of the appropriateness of a bowing acion.

  18. Interaction between an interplanetary magnetic cloud and the Earth's magnetosphere: Motions of the bow shock

    NASA Astrophysics Data System (ADS)

    Wu, D. J.; Chao, J. K.; Lepping, R. P.

    2000-06-01

    An interplanetary magnetic cloud (IMC) is an important solar-terrestrial connection event. It is an ideal object for the study of solar-terrestrial relations and space weather because the Earth's space environment can be affected considerably during an IMC passage. An IMC was observed to pass the Earth during October 18-20, 1995. Wind recorded its interplanetary characteristics at ~175RE upstream of the Earth's bow shock, and ~45 min later, Geotail, being near the nominal location of the dawn bow shock, detected IMC-related multiple bow shock crossings. Using simultaneous measurements from Wind and Geotail, we analyzed, with a semiempirical bow shock model with two parameters, the bow shock motion caused by the interaction of the IMC with the magnetosphere during the passage. We also compared the bow shock motion predicted by the model, and hence the predicted Geotail bow shock crossings, with Geotail observations of the actual crossings. The results showed that the observed multiple bow shock crossings, which were obviously due to temporal variations of the upstream solar wind, can be well explained by the model-predicted bow shock motion.

  19. Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

    PubMed Central

    Hiraga, Shin-ichiro; Alvino, Gina M.; Chang, FuJung; Lian, Hui-yong; Sridhar, Akila; Kubota, Takashi; Brewer, Bonita J.; Weinreich, Michael; Raghuraman, M.K.; Donaldson, Anne D.

    2014-01-01

    Initiation of eukaryotic DNA replication requires phosphorylation of the MCM complex by Dbf4-dependent kinase (DDK), composed of Cdc7 kinase and its activator, Dbf4. We report here that budding yeast Rif1 (Rap1-interacting factor 1) controls DNA replication genome-wide and describe how Rif1 opposes DDK function by directing Protein Phosphatase 1 (PP1)-mediated dephosphorylation of the MCM complex. Deleting RIF1 partially compensates for the limited DDK activity in a cdc7-1 mutant strain by allowing increased, premature phosphorylation of Mcm4. PP1 interaction motifs within the Rif1 N-terminal domain are critical for its repressive effect on replication. We confirm that Rif1 interacts with PP1 and that PP1 prevents premature Mcm4 phosphorylation. Remarkably, our results suggest that replication repression by Rif1 is itself also DDK-regulated through phosphorylation near the PP1-interacting motifs. Based on our findings, we propose that Rif1 is a novel PP1 substrate targeting subunit that counteracts DDK-mediated phosphorylation during replication. Fission yeast and mammalian Rif1 proteins have also been implicated in regulating DNA replication. Since PP1 interaction sites are evolutionarily conserved within the Rif1 sequence, it is likely that replication control by Rif1 through PP1 is a conserved mechanism. PMID:24532715

  20. Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex.

    PubMed

    Hiraga, Shin-Ichiro; Alvino, Gina M; Chang, Fujung; Lian, Hui-Yong; Sridhar, Akila; Kubota, Takashi; Brewer, Bonita J; Weinreich, Michael; Raghuraman, M K; Donaldson, Anne D

    2014-02-15

    Initiation of eukaryotic DNA replication requires phosphorylation of the MCM complex by Dbf4-dependent kinase (DDK), composed of Cdc7 kinase and its activator, Dbf4. We report here that budding yeast Rif1 (Rap1-interacting factor 1) controls DNA replication genome-wide and describe how Rif1 opposes DDK function by directing Protein Phosphatase 1 (PP1)-mediated dephosphorylation of the MCM complex. Deleting RIF1 partially compensates for the limited DDK activity in a cdc7-1 mutant strain by allowing increased, premature phosphorylation of Mcm4. PP1 interaction motifs within the Rif1 N-terminal domain are critical for its repressive effect on replication. We confirm that Rif1 interacts with PP1 and that PP1 prevents premature Mcm4 phosphorylation. Remarkably, our results suggest that replication repression by Rif1 is itself also DDK-regulated through phosphorylation near the PP1-interacting motifs. Based on our findings, we propose that Rif1 is a novel PP1 substrate targeting subunit that counteracts DDK-mediated phosphorylation during replication. Fission yeast and mammalian Rif1 proteins have also been implicated in regulating DNA replication. Since PP1 interaction sites are evolutionarily conserved within the Rif1 sequence, it is likely that replication control by Rif1 through PP1 is a conserved mechanism.

  1. Comparison of Automated Quantitative Reverse Transcription-PCR and Direct Fluorescent-Antibody Detection for Routine Rabies Diagnosis in the United States

    PubMed Central

    Dupuis, Michelle; Brunt, Scott; Appler, Kim; Rudd, Robert

    2015-01-01

    Rabies virus found worldwide and prevalent throughout the United States continues to be a public health concern. Direct-fluorescent antibody (DFA) detection remains the gold standard for rabies virus diagnostics. Assessing the utility of a high-throughput molecular platform such as the QIAsymphony SP/AS, in conjunction with quantitative reverse transcription-PCR (qRT-PCR), to augment or potentially replace the DFA test, was the focus of this project. Here we describe a triplex qRT-PCR assay, including assembly and evaluation for sensitivity, specificity, and ability to detect variants. Additionally, we compared the qRT-PCR assay to the gold standard direct fluorescent-antibody test. More than 1,000 specimens submitted for routine rabies diagnosis were tested to directly compare the two methods. All results were in agreement between the two methods, with one additional specimen detected by qRT-PCR below the limits of the DFA sensitivity. With the proper continued validation for variant detection, molecular methods have a place in routine rabies diagnostics within the United States. PMID:26179300

  2. EGCG reverses human neutrophil elastase-induced migration in A549 cells by directly binding to HNE and by regulating α1-AT

    PubMed Central

    Xiaokaiti, Yilixiati; Wu, Haoming; Chen, Ya; Yang, Haopeng; Duan, Jianhui; Li, Xin; Pan, Yan; Tie, Lu; Zhang, Liangren; Li, Xuejun

    2015-01-01

    Lung carcinogenesis is a complex process that occurs in unregulated inflammatory environment. EGCG has been extensively investigated as a multi-targeting anti-tumor and anti-inflammatory compound. In this study, we demonstrated a novel mechanism by which EGCG reverses the neutrophil elastase-induced migration of A549 cells. We found that neutrophil elastase directly triggered human adenocarcinoma A549 cell migration and that EGCG suppressed the elevation of tumor cell migration induced by neutrophil elastase. We observed that EGCG directly binds to neutrophil elastase and inhibits its enzymatic activity based on the CDOCKER algorithm, MD stimulation by GROMACS, SPR assay and elastase enzymatic activity assay. As the natural inhibitor of neutrophil elastase, α1-antitrypsin is synthesized in tumor cells. We further demonstrated that the expression of α1-antitrypsin was up-regulated after EGCG treatment in neutrophil elastase-treated A549 cells. We preliminarily discovered that the EGCG-mediated induction of α1-antitrypsin expression might be correlated with the regulatory effect of EGCG on the PI3K/Akt pathway. Overall, our results suggest that EGCG ameliorates the neutrophil elastase-induced migration of A549 cells. The mechanism underlying this effect may include two processes: EGCG directly binds to neutrophil elastase and inhibits its enzymatic activity; EGCG enhances the expression of α1-antitrypsin by regulating the PI3K/AKT pathway. PMID:26177797

  3. EGCG reverses human neutrophil elastase-induced migration in A549 cells by directly binding to HNE and by regulating α1-AT

    NASA Astrophysics Data System (ADS)

    Xiaokaiti, Yilixiati; Wu, Haoming; Chen, Ya; Yang, Haopeng; Duan, Jianhui; Li, Xin; Pan, Yan; Tie, Lu; Zhang, Liangren; Li, Xuejun

    2015-07-01

    Lung carcinogenesis is a complex process that occurs in unregulated inflammatory environment. EGCG has been extensively investigated as a multi-targeting anti-tumor and anti-inflammatory compound. In this study, we demonstrated a novel mechanism by which EGCG reverses the neutrophil elastase-induced migration of A549 cells. We found that neutrophil elastase directly triggered human adenocarcinoma A549 cell migration and that EGCG suppressed the elevation of tumor cell migration induced by neutrophil elastase. We observed that EGCG directly binds to neutrophil elastase and inhibits its enzymatic activity based on the CDOCKER algorithm, MD stimulation by GROMACS, SPR assay and elastase enzymatic activity assay. As the natural inhibitor of neutrophil elastase, α1-antitrypsin is synthesized in tumor cells. We further demonstrated that the expression of α1-antitrypsin was up-regulated after EGCG treatment in neutrophil elastase-treated A549 cells. We preliminarily discovered that the EGCG-mediated induction of α1-antitrypsin expression might be correlated with the regulatory effect of EGCG on the PI3K/Akt pathway. Overall, our results suggest that EGCG ameliorates the neutrophil elastase-induced migration of A549 cells. The mechanism underlying this effect may include two processes: EGCG directly binds to neutrophil elastase and inhibits its enzymatic activity; EGCG enhances the expression of α1-antitrypsin by regulating the PI3K/AKT pathway.

  4. MiR-424-5p reversed epithelial-mesenchymal transition of anchorage-independent HCC cells by directly targeting ICAT and suppressed HCC progression

    PubMed Central

    Zhang, Ying; Li, Tao; Guo, Pengbo; Kang, Jia; Wei, Qing; Jia, Xiaoqing; Zhao, Wei; Huai, Wanwan; Qiu, Yumin; Sun, Lei; Han, Lihui

    2014-01-01

    Resistance to anoikis and Epithelial-mesenchymal transition (EMT) are two processes critically involved in cancer metastasis. In this study, we demonstrated that after anchorage deprival, hepatocellular carcinoma (HCC) cells not only resisted anoikis, but also exhibited EMT process. Microarray expression profiling revealed that expression of miR-424-5p was significantly decreased in anoikis-resistant HCC cells. Ectopic overexpression of miR-424-5p was sufficient to reverse resistance to anoikis, block EMT process and inhibit malignant behaviors of HCC cells. Target analysis showed that a potent β-catenin inhibitor, ICAT/CTNNBIP1 was a direct target of miR-424-5p. Further study demonstrated that miR-424-5p reversed resistance to anoikis and EMT of HCCs by directly targeting ICAT and further maintaining the E-cadherin/β-catanin complex on the cellular membrance. In vivo study further demonstrated that miR-424-5p significantly inhibited the tumorigenicity of HCC cells in nude mice. Clinical investigation demonstrated that miR-424-5p was significantly downregulated in HCC tissues compared with that of the non-cancerous liver tissues, and this decreased expression of miR-424-5p was significantly correlated with higher pathological grades and more advanced TNM stages. Therefore, aberrant expression of miR-424-5p is critically involved in resistance to anoikis and EMT during the metastatic process of HCC, and its downregulation significantly contributes to liver cancer progression. PMID:25175916

  5. Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein.

    PubMed

    Kimura, Shoko; Suzuki, Tateki; Chen, Meirong; Kato, Koji; Yu, Jian; Nakamura, Akiyoshi; Tanaka, Isao; Yao, Min

    2016-03-01

    Thg1-like protein (TLP) catalyzes the addition of a nucleotide to the 5'-end of truncated transfer RNA (tRNA) species in a Watson-Crick template-dependent manner. The reaction proceeds in two steps: the activation of the 5'-end by adenosine 5'-triphosphate (ATP)/guanosine 5'-triphosphate (GTP), followed by nucleotide addition. Structural analyses of the TLP and its reaction intermediates have revealed the atomic detail of the template-dependent elongation reaction in the 3'-5' direction. The enzyme creates two substrate binding sites for the first- and second-step reactions in the vicinity of one reaction center consisting of two Mg(2+) ions, and the two reactions are executed at the same reaction center in a stepwise fashion. When the incoming nucleotide is bound to the second binding site with Watson-Crick hydrogen bonds, the 3'-OH of the incoming nucleotide and the 5'-triphosphate of the tRNA are moved to the reaction center where the first reaction has occurred. That the 3'-5' elongation enzyme performs this elaborate two-step reaction in one catalytic center suggests that these two reactions have been inseparable throughout the process of protein evolution. Although TLP and Thg1 have similar tetrameric organization, the tRNA binding mode of TLP is different from that of Thg1, a tRNA(His)-specific G-1 addition enzyme. Each tRNA(His) binds to three of the four Thg1 tetramer subunits, whereas in TLP, tRNA only binds to a dimer interface and the elongation reaction is terminated by measuring the accepter stem length through the flexible β-hairpin. Furthermore, mutational analyses show that tRNA(His) is bound to TLP in a similar manner as Thg1, thus indicating that TLP has a dual binding mode.

  6. Template-dependent nucleotide addition in the reverse (3′-5′) direction by Thg1-like protein

    PubMed Central

    Kimura, Shoko; Suzuki, Tateki; Chen, Meirong; Kato, Koji; Yu, Jian; Nakamura, Akiyoshi; Tanaka, Isao; Yao, Min

    2016-01-01

    Thg1-like protein (TLP) catalyzes the addition of a nucleotide to the 5′-end of truncated transfer RNA (tRNA) species in a Watson-Crick template–dependent manner. The reaction proceeds in two steps: the activation of the 5′-end by adenosine 5′-triphosphate (ATP)/guanosine 5′-triphosphate (GTP), followed by nucleotide addition. Structural analyses of the TLP and its reaction intermediates have revealed the atomic detail of the template-dependent elongation reaction in the 3′-5′ direction. The enzyme creates two substrate binding sites for the first- and second-step reactions in the vicinity of one reaction center consisting of two Mg2+ ions, and the two reactions are executed at the same reaction center in a stepwise fashion. When the incoming nucleotide is bound to the second binding site with Watson-Crick hydrogen bonds, the 3′-OH of the incoming nucleotide and the 5′-triphosphate of the tRNA are moved to the reaction center where the first reaction has occurred. That the 3′-5′ elongation enzyme performs this elaborate two-step reaction in one catalytic center suggests that these two reactions have been inseparable throughout the process of protein evolution. Although TLP and Thg1 have similar tetrameric organization, the tRNA binding mode of TLP is different from that of Thg1, a tRNAHis-specific G−1 addition enzyme. Each tRNAHis binds to three of the four Thg1 tetramer subunits, whereas in TLP, tRNA only binds to a dimer interface and the elongation reaction is terminated by measuring the accepter stem length through the flexible β-hairpin. Furthermore, mutational analyses show that tRNAHis is bound to TLP in a similar manner as Thg1, thus indicating that TLP has a dual binding mode. PMID:27051866

  7. Pseudomorphic GeSn/Ge(001) quantum wells: Examining indirect band gap bowing

    SciTech Connect

    Tonkikh, Alexander A.; Eisenschmidt, Christian; Schmidt, Georg; Talalaev, Vadim G.; Zakharov, Nikolay D.; Werner, Peter; Schilling, Joerg

    2013-07-15

    A study of the bandgap character of compressively strained GeSn{sub 0.060-0.091}/Ge(001) quantum wells grown by molecular beam epitaxy is reported. The built-in strain in GeSn wells leads to an increased separation between L and {Gamma} conduction band minima. The prevalent indirect interband transitions in GeSn were probed by photoluminescence spectroscopy. As a result we could simulate the L-valley bowing parameter in GeSn alloys, b{sub L} = 0.80 {+-} 0.06 eV at 10 K. From this we conclude that even compressively strained GeSn/Ge(001) alloys could become direct band gap semiconductors at the Sn-fraction higher than 17.0 at. %.

  8. The Geomagnetic Field During a Reversal

    NASA Technical Reports Server (NTRS)

    Heirtzler, James R.

    2003-01-01

    By modifying the IGRF it is possible to learn what may happen to the geomagnetic field during a geomagnetic reversal. If the entire IGRF reverses then the declination and inclination only reverse when the field strength is zero. If only the dipole component of the IGRF reverses a large geomagnetic field remains when the dipole component is zero and he direction of the field at the end of the reversal is not exactly reversed from the directions at the beginning of the reversal.

  9. An unusual case of pediatric bow hunter's stroke

    PubMed Central

    Anene-Maidoh, Tony I.; Vega, Rafael A.; Fautheree, Gregory L.; Reavey-Cantwell, John F.

    2013-01-01

    Background: Bow Hunter's syndrome/stroke is defined as symptomatic, vertebrobasilar insufficiency provoked by physiologic head rotation. It is a diagnostically challenging cause of posterior circulation stroke in children. While there have been prior reports of this rare disorder, we describe an exceptional case of pediatric Bow Hunter's stroke resulting from a near complete occlusion the right vertebral artery (VA) secondary to an anomalous spur emanating from the right occipital condyle. Surgical and endovascular options and approaches are also detailed herein. Case Description: A 16-year-old male presented with multiple posterior circulation ischemic strokes. A dynamic computerized tomography angiogram performed with the patient's head in a rotated position revealed a near complete occlusion of the V3 segment of the right VA from a bone spur arising from his occipital condyle. The spur caused a focal dissection of the distal right VA with associated thrombus. He was initially managed with a cervical collar, antiplatelet therapy with aspirin 81 mg and anticoagulation with coumadin (INR goal 2-3) for 3 months. Despite the management plan, he had a subsequent thromboembolic event and a right VA sacrifice with coil embolization was then performed. At the 3-month follow-up, the patient was doing well with no reports of any subsequent strokes. Conclusion: We report the first reported pediatric case of Bow Hunter's stroke due to dynamic right VA occlusion from an occipital condylar bone spur. The vascular compression from this spur led to a right VA dissection and thrombus formation and ultimately caused multiple posterior circulation thromboembolic strokes. Endovascular treatment options including vessel sacrifice should be considered in cases that have failed maximal medical management. PMID:24340230

  10. Electric field measurements at subcritical, oblique bow shock crossings

    NASA Technical Reports Server (NTRS)

    Wygant, J. R.; Bensadoun, M.; Mozer, F. S.

    1987-01-01

    ISEE-1 electric field measurements at three oblique, subcritical dispersive bow shock crossings are presented. The potential drops across the shock due to the large spatial scale normal component of the electric field were found to vary between 340 and 520 V. The measurements provide the first observations in a space plasma of the oscillations in the normal component of the electric field connected with the whistler precursor phase standing at a collisionless shock. Intense, rapidly varying electric fields with peak amplitudes ranging up to 100 mV/m were observed at the magnetic ramp of the shock in the high time resolution data.

  11. Binary index for assessing local bow shock obliquity.

    NASA Technical Reports Server (NTRS)

    Greenstadt, E. W.

    1972-01-01

    The earth's collisionless plasma bow shock has, overall, a nonuniform structure whose magnetic profile is simultaneously that of a monotonic or laminar perpendicular shock and of a multigradient oblique shock, depending on the local orientation of the interplanetary field to the nominal shock surface. A 'pulsation index' Ip has been devised from empirical results to provide a simple convenient means of assessing the probable local character of the shock's structure; Ip = 0 or 1, according to whether local field geometry favors perpendicular or oblique structure, respectively, at a chosen point of observation on the nominal shock surface.

  12. Radial head dislocation with acute plastic bowing of the ulna.

    PubMed

    Sai, Shigaku; Fujii, Katsuyuki; Chino, Hiroyuki; Inoue, Junichi

    2005-01-01

    Five radial head dislocations with acute plastic bowing of the ulna in patients aged 6-12 years were reviewed. Closed reduction was successful in two, and open reduction was required in three patients in whom treatment was started more than 2 weeks after injury. In one child who presented 2 months after injury, realignment by osteotomy of the ulna as well as open reduction of the radial head was necessary. Follow-up evaluations at 6-24 months revealed good clinical outcomes in all patients. Awareness of this type of radial head dislocation is important to avoid delays in diagnosis and treatment. PMID:15666132

  13. Detection of Magnaporthe oryzae chrysovirus 1 in Japan and establishment of a rapid, sensitive and direct diagnostic method based on reverse transcription loop-mediated isothermal amplification.

    PubMed

    Komatsu, Ken; Urayama, Syun-Ichi; Katoh, Yu; Fuji, Shin-Ichi; Hase, Shu; Fukuhara, Toshiyuki; Arie, Tsutomu; Teraoka, Tohru; Moriyama, Hiromitsu

    2016-02-01

    Magnaporthe oryzae chrysovirus 1 (MoCV1) is a mycovirus with a dsRNA genome that infects the rice blast fungus Magnaporthe oryzae and impairs its growth. To date, MoCV1 has only been found in Vietnamese isolates of M. oryzae, and the distribution of this virus in M. oryzae isolates from other parts of the world remains unknown. In this study, using a one-step reverse transcription PCR (RT-PCR) assay, we detected a MoCV1-related virus in M. oryzae in Japan (named MoCV1-AK) whose sequence shares considerable similarity with that of the MoCV1 Vietnamese isolate. To establish a system for a comprehensive survey of MoCV1 infection in the field, we developed a reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for direct detection of the virus. The sensitivity of the RT-LAMP assay was at least as high as that of the one-step RT-PCR assay. In addition, we detected MoCV1-AK in M. oryzae-infected oatmeal agar plates and lesions on rice leaves using the RT-LAMP assay without dsRNA extraction, by simple sampling with a toothpick. Preliminary screening of MoCV1 in Japanese M. oryzae isolates indicated that MoCV1 is currently distributed in rice fields in Japan. Our results provide a first example of the application of RT-LAMP for the detection of mycoviruses, which will accelerate surveys for mycovirus infection. PMID:26547578

  14. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments.

    PubMed

    Haupt, Lois J; Kazmi, Faraz; Ogilvie, Brian W; Buckley, David B; Smith, Brian D; Leatherman, Sarah; Paris, Brandy; Parkinson, Oliver; Parkinson, Andrew

    2015-11-01

    In the present study, we conducted a retrospective analysis of 343 in vitro experiments to ascertain whether observed (experimentally determined) values of Ki for reversible cytochrome P450 (P450) inhibition could be reliably predicted by dividing the corresponding IC₅₀ values by two, based on the relationship (for competitive inhibition) in which Ki = IC₅₀/2 when [S] (substrate concentration) = Km (Michaelis-Menten constant). Values of Ki and IC₅₀ were determined under the following conditions: 1) the concentration of P450 marker substrate, [S], was equal to Km (for IC₅₀ determinations) and spanned Km (for Ki determinations); 2) the substrate incubation time was short (5 minutes) to minimize metabolism-dependent inhibition and inhibitor depletion; and 3) the concentration of human liver microsomes was low (0.1 mg/ml or less) to maximize the unbound fraction of inhibitor. Under these conditions, predicted Ki values, based on IC₅₀/2, correlated strongly with experimentally observed Ki determinations [r = 0.940; average fold error (AFE) = 1.10]. Of the 343 predicted Ki values, 316 (92%) were within a factor of 2 of the experimentally determined Ki values, and only one value fell outside a 3-fold range. In the case of noncompetitive inhibitors, Ki values predicted from IC₅₀/2 values were overestimated by a factor of nearly 2 (AFE = 1.85; n = 13), which is to be expected because, for noncompetitive inhibition, Ki = IC₅₀ (not IC₅₀/2). The results suggest that, under appropriate experimental conditions with the substrate concentration equal to Km, values of Ki for direct, reversible inhibition can be reliably estimated from values of IC₅₀/2. PMID:26354951

  15. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments.

    PubMed

    Haupt, Lois J; Kazmi, Faraz; Ogilvie, Brian W; Buckley, David B; Smith, Brian D; Leatherman, Sarah; Paris, Brandy; Parkinson, Oliver; Parkinson, Andrew

    2015-11-01

    In the present study, we conducted a retrospective analysis of 343 in vitro experiments to ascertain whether observed (experimentally determined) values of Ki for reversible cytochrome P450 (P450) inhibition could be reliably predicted by dividing the corresponding IC₅₀ values by two, based on the relationship (for competitive inhibition) in which Ki = IC₅₀/2 when [S] (substrate concentration) = Km (Michaelis-Menten constant). Values of Ki and IC₅₀ were determined under the following conditions: 1) the concentration of P450 marker substrate, [S], was equal to Km (for IC₅₀ determinations) and spanned Km (for Ki determinations); 2) the substrate incubation time was short (5 minutes) to minimize metabolism-dependent inhibition and inhibitor depletion; and 3) the concentration of human liver microsomes was low (0.1 mg/ml or less) to maximize the unbound fraction of inhibitor. Under these conditions, predicted Ki values, based on IC₅₀/2, correlated strongly with experimentally observed Ki determinations [r = 0.940; average fold error (AFE) = 1.10]. Of the 343 predicted Ki values, 316 (92%) were within a factor of 2 of the experimentally determined Ki values, and only one value fell outside a 3-fold range. In the case of noncompetitive inhibitors, Ki values predicted from IC₅₀/2 values were overestimated by a factor of nearly 2 (AFE = 1.85; n = 13), which is to be expected because, for noncompetitive inhibition, Ki = IC₅₀ (not IC₅₀/2). The results suggest that, under appropriate experimental conditions with the substrate concentration equal to Km, values of Ki for direct, reversible inhibition can be reliably estimated from values of IC₅₀/2.

  16. DOUBLE BOW SHOCKS AROUND YOUNG, RUNAWAY RED SUPERGIANTS: APPLICATION TO BETELGEUSE

    SciTech Connect

    Mackey, Jonathan; Mohamed, Shazrene; Neilson, Hilding R.; Langer, Norbert; Meyer, Dominique M.-A.

    2012-05-20

    A significant fraction of massive stars are moving supersonically through the interstellar medium (ISM), either due to disruption of a binary system or ejection from their parent star cluster. The interaction of their wind with the ISM produces a bow shock. In late evolutionary stages these stars may undergo rapid transitions from red to blue and vice versa on the Hertzsprung-Russell diagram, with accompanying rapid changes to their stellar winds and bow shocks. Recent three-dimensional simulations of the bow shock produced by the nearby runaway red supergiant (RSG) Betelgeuse, under the assumption of a constant wind, indicate that the bow shock is very young (<30, 000 years old), hence Betelgeuse may have only recently become an RSG. To test this possibility, we have calculated stellar evolution models for single stars which match the observed properties of Betelgeuse in the RSG phase. The resulting evolving stellar wind is incorporated into two-dimensional hydrodynamic simulations in which we model a runaway blue supergiant (BSG) as it undergoes the transition to an RSG near the end of its life. We find that the collapsing BSG wind bubble induces a bow shock-shaped inner shell around the RSG wind that resembles Betelgeuse's bow shock, and has a similar mass. Surrounding this is the larger-scale retreating bow shock generated by the now defunct BSG wind's interaction with the ISM. We suggest that this outer shell could explain the bar feature located (at least in projection) just in front of Betelgeuse's bow shock.

  17. 77 FR 19661 - City of Broken Bow, OK; Notice of Technical Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission City of Broken Bow, OK; Notice of Technical Conference March 21, 2012. Take.... Forest Service's Hochatown Office, Route 4, Broken Bow, OK 74728. All local, state, and federal...

  18. The nonspecificity of the antral bowing sign in maxillary sinus pathology.

    PubMed

    Som, P M; Shugar, J M; Cohen, B A; Biller, H F

    1981-06-01

    Although bowing of the posterior antral wall occurs most commonly with juvenile angiofibroma, it can occur with any slow growing noninvasive lesion involving the retromaxillary region. Cases of schwannomas, a lymphoepithelioma, and a fibrous histiocytoma are presented as examples of the nonspecificity of the antral bowing sign.

  19. Transonic flow past a wedge profile with detached bow wave

    NASA Technical Reports Server (NTRS)

    Vincenti, Walter G; Wagoner, Cleo B

    1952-01-01

    A theoretical study has been made of the aerodynamic characteristics at zero angle of attack of a thin, doubly symmetrical double-wedge profile in the range of supersonic flight speed in which the bow wave is detached. The analysis utilizes the equations of the transonic small-disturbance theory and involves no assumptions beyond those implicit in this theory. The mixed flow about the front half of the profile is calculated by relaxation solution of boundary conditions along the shock polar and sonic line. The purely subsonic flow about the rear of the profile is found by means of the method of characteristics specialized to the transonic small-disturbance theory. Complete calculations were made for four values of the transonic similarity parameter. These were found sufficient to bridge the gap between the previous results of Guderley and Yoshihara at a Mach number of 1 and the results which are readily obtained when the bow wave is attached and the flow is completely supersonic.

  20. Quasilinear simulations of interplanetary shocks and Earth's bow shock

    NASA Astrophysics Data System (ADS)

    Afanasiev, Alexandr; Battarbee, Markus; Ganse, Urs; Vainio, Rami; Palmroth, Minna; Pfau-Kempf, Yann; Hoilijoki, Sanni; von Alfthan, Sebastian

    2016-04-01

    We have developed a new self-consistent Monte Carlo simulation model for particle acceleration in shocks. The model includes a prescribed large-scale magnetic field and plasma density, temperature and velocity profiles and a self-consistently computed incompressible ULF foreshock under the quasilinear approximation. Unlike previous analytical treatments, our model is time dependent and takes full account of the anisotropic particle distributions and scattering in the wave-particle interaction process. We apply the model to the problem of particle acceleration at traveling interplanetary (IP) shocks and Earth's bow shock and compare the results with hybrid-Vlasov simulations and spacecraft observations. A qualitative agreement in terms of spectral shape of the magnetic fluctuations and the polarization of the unstable mode is found between the models and the observations. We will quantify the differences of the models and explore the region of validity of the quasilinear approach in terms of shock parameters. We will also compare the modeled IP shocks and the bow shock, identifying the similarities and differences in the spectrum of accelerated particles and waves in these scenarios. The work has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 637324 (HESPERIA). The Academy of Finland is thanked for financial support. We acknowledge the computational resources provided by CSC - IT Centre for Science Ltd., Espoo.

  1. Cluster Close Separation at the Bow Shock Campaign: Initial Results.

    NASA Astrophysics Data System (ADS)

    Balikhin, M. A.; Sagdeev, R.; Walker, S. N.; Malkov, M.; Krasnoselskikh, V.; Khotyaintsev, Y. V.; Fazakerley, A. N.; Doss, N.

    2015-12-01

    The Cluster close separation at the terrestrial bow shock campaign was aimed at probing the terrestrial bow shock front using multi-scale spacecraft separations. The closest separation (< 10 km) was achieved between Cluster 3 and Cluster 4. The separation of two other spacecraft from this pair was in the range 100-1000 km. The data from this Cluster campaign have been used to study the fine structure of the magnetic ramp. It is shown that the magnetic field perturbations observed within the ramp along the shock normal possess spatial scales a few times shorter than the ramp region itself, and are accompanied by variations in the electric field with magnitudes of a few tens mV/m. Using dual spacecraft measurements enables us to show that in the plane of the shock front the characteristic width of these structures corresponds to electron scales. Comparison of the magnetic field profile obtained from Cluster 3 and 4 indicates possibility that the initial stage of the front reformation is observed. However alternative explanations ( kinetic instabilities, corrugation instability) are also discussed.

  2. Lunar Surface Potential Increases during Terrestrial Bow Shock Traversals

    NASA Technical Reports Server (NTRS)

    Collier, Michael R.; Stubbs, Timothy J.; Hills, H. Kent; Halekas, Jasper; Farrell, William M.; Delory, Greg T.; Espley, Jared; Freeman, John W.; Vondrak, Richard R.; Kasper, Justin

    2009-01-01

    Since the Apollo era the electric potential of the Moon has been a subject of interest and debate. Deployed by three Apollo missions, Apollo 12, Apollo 14 and Apollo 15, the Suprathermal Ion Detector Experiment (SIDE) determined the sunlit lunar surface potential to be about +10 Volts using the energy spectra of lunar ionospheric thermal ions accelerated toward the Moon. We present an analysis of Apollo 14 SIDE "resonance" events that indicate the lunar surface potential increases when the Moon traverses the dawn bow shock. By analyzing Wind spacecraft crossings of the terrestrial bow shock at approximately this location and employing current balancing models of the lunar surface, we suggest causes for the increasing potential. Determining the origin of this phenomenon will improve our ability to predict the lunar surface potential in support of human exploration as well as provide models for the behavior of other airless bodies when they traverse similar features such as interplanetary shocks, both of which are goals of the NASA Lunar Science Institute's Dynamic Response of the Environment At the Moon (DREAM) team.

  3. HELIOSPHERIC STRUCTURE: THE BOW WAVE AND THE HYDROGEN WALL

    SciTech Connect

    Zank, G. P.; Heerikhuisen, J.; Pogorelov, N. V.; Zirnstein, E.; Wood, B. E.; McComas, D. J.

    2013-01-20

    Recent IBEX observations indicate that the local interstellar medium (LISM) flow speed is less than previously thought (23.2 km s{sup -1} rather than 26 km s{sup -1}). Reasonable LISM plasma parameters indicate that the LISM flow may be either marginally super-fast magnetosonic or sub-fast magnetosonic. This raises two challenging questions: (1) Can a LISM model that is barely super-fast or sub-fast magnetosonic account for Ly{alpha} observations that rely critically on the additional absorption provided by the hydrogen wall (H-wall)? and (2) If the LISM flow is weakly super-fast magnetosonic, does the transition assume the form of a traditional shock or does neutral hydrogen (H) mediate shock dissipation and hence structure through charge exchange? Both questions are addressed using three three-dimensional self-consistently coupled magnetohydrodynamic plasma-kinetic H models with different LISM magnetic field strengths (2, 3, and 4 {mu}G) as well as plasma and neutral H number densities. The 2 and 3 {mu}G models are fast magnetosonic far upwind of the heliopause whereas the 4 {mu}G model is fully subsonic. The 2 {mu}G model admits a broad ({approx}50-75 AU) bow-shock-like structure. The 3 {mu}G model has a smooth super-fast-sub-fast magnetosonic transition that resembles a very broad, {approx}200 AU thick, bow wave. A theoretical analysis shows that the transition from a super-fast to a sub-fast magnetosonic downstream state is due to the charge exchange of fast neutral H and hot neutral H created in the supersonic solar wind and hot inner heliosheath, respectively. For both the 2 {mu}G and the 3 {mu}G models, the super-fast magnetosonic LISM flow passes through a critical point located where the fast magnetosonic Mach number M = 1 and Q{sub e} = {gamma}/({gamma} - 1)UQ{sub m} , where Q{sub e} and Q{sub m} are the plasma energy and momentum source terms due to charge exchange, U is the LISM flow speed, and {gamma} is the plasma adiabatic index. Because the Mach

  4. Bow Shock Leads the Way for a Speeding Hot Jupiter

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2015-09-01

    As hot Jupiters whip around their host stars, their speeds can exceed the speed of sound in the surrounding material, theoretically causing a shock to form ahead of them. Now, a study has reported the detection of such a shock ahead of transiting exoplanet HD 189733b, providing a potential indicator of the remarkably strong magnetic field of the planet.Rushing PlanetsDue to their proximity to their hosts, hot Jupiters move very quickly through the stellar wind and corona surrounding the star. When this motion is supersonic, the material ahead of the planet can be compressed by a bow shock and for a transiting hot Jupiter, this shock will cross the face of the host star in advance of the planets transit.In a recent study, a team of researchers by Wilson Cauley of Wesleyan University report evidence of just such a pre-transit. The teams target is exoplanet HD 189733b, one of the closest hot Jupiters to our solar system. When the authors examined high-resolution transmission spectra of this system, they found that prior to the optical transit of the planet, there was a large dip in the transmission of the first three hydrogen Balmer lines. This could well be the absorption of an optically-thick bow shock as it moves past the face of the star.Tremendous MagnetismOperating under this assumption, the authors create a model of the absorption expected from a hot Jupiter transiting with a bow shock ahead of it. Using this model, they show that a shock leading the planet at a distance of 12.75 times the planets radius reproduces the key features of the transmission spectrum.This stand-off distance is surprisingly large. Assuming that the location of the bow shock is set by the point where the planets magnetospheric pressure balances the pressure of the stellar wind or corona that it passes through, the planetary magnetic field would have to be at least 28 Gauss. This is seven times the strength of Jupiters magnetic field!Understanding the magnetic fields of exoplanets is

  5. Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study.

    PubMed

    Fiorini, Ada; Sultana, Rukhsana; Förster, Sarah; Perluigi, Marzia; Cenini, Giovanna; Cini, Chiara; Cai, Jian; Klein, Jon B; Farr, Susan A; Niehoff, Michael L; Morley, John E; Kumar, Vijaya B; Allan Butterfield, D

    2013-12-01

    Amyloid β-peptide (Aβ) plays a central role in the pathophysiology of Alzheimer's disease (AD) through the induction of oxidative stress. This peptide is produced by proteolytic cleavage of amyloid precursor protein (APP) by the action of β- and γ-secretases. Previous studies demonstrated that reduction of Aβ, using an antisense oligonucleotide (AO) directed against the Aβ region of APP, reduced oxidative stress-mediated damage and prevented or reverted cognitive deficits in senescence-accelerated prone mice (SAMP8), a useful animal model for investigating the events related to Aβ pathology and possibly to the early phase of AD. In the current study, aged SAMP8 were treated by AO directed against PS-1, a component of the γ-secretase complex, and tested for learning and memory in T-maze foot shock avoidance and novel object recognition. Brain tissue was collected to identify the decrease of oxidative stress and to evaluate the proteins that are differently expressed and oxidized after the reduction in free radical levels induced by Aβ. We used both expression proteomics and redox proteomics approaches. In brain of AO-treated mice a decrease of oxidative stress markers was found, and the proteins identified by proteomics as expressed differently or nitrated are involved in processes known to be impaired in AD. Our results suggest that the treatment with AO directed against PS-1 in old SAMP8 mice reverses learning and memory deficits and reduces Aβ-mediated oxidative stress with restoration to the normal condition and identifies possible pharmacological targets to combat this devastating dementing disease.

  6. Comparison of picked-up protons and water group ions upstream of comet Halley's bow shock

    SciTech Connect

    Neugebauer, M. ); Coates, A.J. ); Neubauer, F.M. )

    1990-11-01

    Data are presented on the properties of picked-up cometary protons and water group (WG) ions observed upstream of the bow shock of comet Halley by the ion mass spectrometer and Johnstone plasma analyzer experiments on the Giotto spacecraft. The number of WG ions exceeded the number of cometary protons at cometocentric distances r < 1.3 {times} 10{sup 6} km, while the WG mass density exceeded the proton mass density when r < 6 {times} 10{sup 6} km. The small scale variations of proton and WG densities were well correlated, which argues against the expanding halo model which has been used to explain the quasi-periodicity of energetic particles observed by VEGA and Giotto. Two parameters are used to describe the pitch angle distributions of the picked-up ions: a 10% width, which is the full angular width at 10% of the maximum of the pitch angle distribution, and a mean width. The cometocentric distance profiles of both parameters exhibited a great deal of scatter, and both parameters showed a steeper average radial gradient for WG ions than for protons. The 10% widths of WG ions were consistent with less than 10:1 anisotropies for r < 2.5 {times} 10{sup 6} km, but the proton anisotropy did not drop below 10:1 until the spacecraft entered the foreshock region at r = 1.4 {times} 10{sup 6} km. After subtraction of the variation in field direction, the mean width of the proton pitch angle distribution was nearly independent of distance everywhere outside the shock. The WG mean width, on the other hand, increased with increasing WG density and with increasing angle {alpha} between the interplanetary field and the solar wind velocity vector. No increase in shell radii, due to either adiabatic compression or first-order Fermi acceleration, could be discerned for either ion species until the spacecraft was very close to the bow shock.

  7. A cephalometric evaluation of high-pull molar headgear and face-bow neck strap therapy.

    PubMed

    Brown, P

    1978-12-01

    The effects of two different extraoral appliances were evaluated over a 1-year period. Of the thirty-seven cases selected for study, twenty were treated with a face-bow neck strap and seventeen were treated with a high-pull molar headgear. Patients ranged in age from 10.10 to 16.6 years and averaged 13.4 years. The appliances exerted less than 600 Gm. of force per side and were worn for 12 to 16 hours per day. All cases were fully banded, and extraction and nonextraction treatment were included. An analysis of pretreatment data revealed a high degree of selection. Patients selected for high-pull treatment generally exhibited larger anterior face heights, steeper mandibular plane angles, and a greater amount of tooth eruption of the upper first molars than the patients selected for neck strap therapy. A control group of ten untreated subjects was matched to each treatment group to permit assessment of the impact of treatment on growth. Relative to normal growth, treatment with face-bow neck strap traction tended to direct the maxilla and mandible downward and backward. The palatal plane was lowered anteriorly and point A was retracted. The maxillary molars were extruded, and concomitantly an increase in anterior face height and mandibular plane angle was observed. On the other hand, the high-pull molar headgear traction resulted only in increased mandibular molar eruption. However, there was also a nonsignificant tendency for point A to be held back and for lower anterior face height to increase. The comparison of the two treatment samples revealed that the functional occlusal plane was tipped down at the back as the maxillary molars were more extruded in the neck strap sample. In the high-pull sample, the functional occlusal plane was unchanged and the mandibular molars were more extruded than they were in the neck strap group.

  8. Simulation of the oscillation regimes of bowed bars: a non-linear modal approach

    NASA Astrophysics Data System (ADS)

    Inácio, Octávio; Henrique, Luís.; Antunes, José

    2003-06-01

    It is still a challenge to properly simulate the complex stick-slip behavior of multi-degree-of-freedom systems. In the present paper we investigate the self-excited non-linear responses of bowed bars, using a time-domain modal approach, coupled with an explicit model for the frictional forces, which is able to emulate stick-slip behavior. This computational approach can provide very detailed simulations and is well suited to deal with systems presenting a dispersive behavior. The effects of the bar supporting fixture are included in the model, as well as a velocity-dependent friction coefficient. We present the results of numerical simulations, for representative ranges of the bowing velocity and normal force. Computations have been performed for constant-section aluminum bars, as well as for real vibraphone bars, which display a central undercutting, intended to help tuning the first modes. Our results show limiting values for the normal force FN and bowing velocity ẏbow for which the "musical" self-sustained solutions exist. Beyond this "playability space", double period and even chaotic regimes were found for specific ranges of the input parameters FN and ẏbow. As also displayed by bowed strings, the vibration amplitudes of bowed bars also increase with the bow velocity. However, in contrast to string instruments, bowed bars "slip" during most of the motion cycle. Another important difference is that, in bowed bars, the self-excited motions are dominated by the system's first mode. Our numerical results are qualitatively supported by preliminary experimental results.

  9. Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection.

    PubMed

    Li, Yongtao; Whitaker, Joshua S; McCarty, Christina L

    2012-07-01

    A large volume direct aqueous injection method was developed for the analysis of iodinated haloacetic acids in drinking water by using reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry in the negative ion mode. Both the external and internal standard calibration methods were studied for the analysis of monoiodoacetic acid, chloroiodoacetic acid, bromoiodoacetic acid, and diiodoacetic acid in drinking water. The use of a divert valve technique for the mobile phase solvent delay, along with isotopically labeled analogs used as internal standards, effectively reduced and compensated for the ionization suppression typically caused by coexisting common inorganic anions. Under the optimized method conditions, the mean absolute and relative recoveries resulting from the replicate fortified deionized water and chlorinated drinking water analyses were 83-107% with a relative standard deviation of 0.7-11.7% and 84-111% with a relative standard deviation of 0.8-12.1%, respectively. The method detection limits resulting from the external and internal standard calibrations, based on seven fortified deionized water replicates, were 0.7-2.3 ng/L and 0.5-1.9 ng/L, respectively.

  10. STEREO and Wind Observations of Intense Cyclotron Harmonic Waves at the Earth's Bow Shock and Inside the Magnetosheath

    NASA Technical Reports Server (NTRS)

    Breneman, A. W.; Cattell, C.

    2013-01-01

    We present the first observations of electron cyclotron harmonic waves at the Earth's bow shock from STEREO and Wind burst waveform captures. These waves are observed at magnetic field gradients at a variety of shock geometries ranging from quasi-parallel to nearly perpendicular along with whistler mode waves, ion acoustic waves, and electrostatic solitary waves. Large amplitude cyclotron harmonic waveforms are also observed in the magnetosheath in association with magnetic field gradients convected past the bow shock. Amplitudes of the cyclotron harmonic waves range from a few tens to more than 500 millivolts/meter peak-peak. A comparison between the short (15 meters) and long (100 meters) Wind spin plane antennas shows a similar response at low harmonics and a stronger response on the short antenna at higher harmonics. This indicates that wavelengths are not significantly larger than 100 meters, consistent with the electron cyclotron radius. Waveforms are broadband and polarizations are distinctively comma-shaped with significant power both perpendicular and parallel to the magnetic field. Harmonics tend to be more prominent in the perpendicular directions. These observations indicate that the waves consist of a combination of perpendicular Bernstein waves and field-aligned waves without harmonics. A likely source is the electron cyclotron drift instability which is a coupling between Bernstein and ion acoustic waves. These waves are the most common type of high-frequency wave seen by STEREO during bow shock crossings and magnetosheath traversals and our observations suggest that they are an important component of the high-frequency turbulent spectrum in these regions.

  11. CHONDRULE FORMATION IN BOW SHOCKS AROUND ECCENTRIC PLANETARY EMBRYOS

    SciTech Connect

    Morris, Melissa A.; Desch, Steven J.; Athanassiadou, Themis; Boley, Aaron C.

    2012-06-10

    Recent isotopic studies of Martian meteorites by Dauphas and Pourmand have established that large ({approx}3000 km radius) planetary embryos existed in the solar nebula at the same time that chondrules-millimeter-sized igneous inclusions found in meteorites-were forming. We model the formation of chondrules by passage through bow shocks around such a planetary embryo on an eccentric orbit. We numerically model the hydrodynamics of the flow and find that such large bodies retain an atmosphere with Kelvin-Helmholtz instabilities allowing mixing of this atmosphere with the gas and particles flowing past the embryo. We calculate the trajectories of chondrules flowing past the body and find that they are not accreted by the protoplanet, but may instead flow through volatiles outgassed from the planet's magma ocean. In contrast, chondrules are accreted onto smaller planetesimals. We calculate the thermal histories of chondrules passing through the bow shock. We find that peak temperatures and cooling rates are consistent with the formation of the dominant, porphyritic texture of most chondrules, assuming a modest enhancement above the likely solar nebula average value of chondrule densities (by a factor of 10), attributable to settling of chondrule precursors to the midplane of the disk or turbulent concentration. We calculate the rate at which a planetary embryo's eccentricity is damped and conclude that a single planetary embryo scattered into an eccentric orbit can, over {approx}10{sup 5} years, produce {approx}10{sup 24} g of chondrules. In principle, a small number (1-10) of eccentric planetary embryos can melt the observed mass of chondrules in a manner consistent with all known constraints.

  12. Global Hybrid Simulations: Applications to Bow Shock and Dayside Magnetosphere

    NASA Astrophysics Data System (ADS)

    Omidi, Nojan; Sibeck, David; Phan, Tai; Eastwood, Jonathan

    With the advent of global hybrid (kinetic ions, fluid electrons) simulations it has become possible to examine magnetospheric processes and their interconnections on ion time and spatial scales. This capability combined with multi-spacecraft missions such as Cluster and THEMIS provide an unprecedented opportunity to perform detailed, quantitative comparisons between theory and observations to examine basic paradigms and build new ones. To illustrate this capability, this presentation focuses on a number of topics related to the bow shock and dayside magnetosphere. One topic concerns the formation of the ion foreshock boundary predicted by global hybrid simulations and their relationship to the observed phenomenon of foreshock cavities. Interaction of solar wind discontinuities with the bow shock lead to a variety of phenomena such as hot flow anomalies (HFAs) or initiation of magnetic reconnection in the magnetosheath. We show examples of both processes in hybrid simulations and comparisons with spacecraft observations. In regards to HFAs, recent THEMIS measurements provide detailed information on their magnetosheath signatures. Understanding of these signatures and impacts on the magnetosphere/ionosphere system remains an important topic of investigation. Magnetic reconnection in the magnetosheath provides an opportunity to examine this important process in relative isolation and symmetric plasma conditions. Here, we address the impact of discontinuity thickness and magnetic shear on the nature of the resulting reconnection and the implications for time dependency and geometry (anti-parallel vs component) of reconnection at the magnetopause. The final topic of the presentation is the formation of flux transfer events (FTEs) at the magnetopause and their subsequent motion and interaction with the cusps. This interaction involves secondary magnetic reconnection and acceleration of plasma into the cusp. As we illustrate, this process may account for the formation of

  13. Chondrule Formation in Bow Shocks around Eccentric Planetary Embryos

    NASA Astrophysics Data System (ADS)

    Morris, Melissa A.; Boley, Aaron C.; Desch, Steven J.; Athanassiadou, Themis

    2012-06-01

    Recent isotopic studies of Martian meteorites by Dauphas & Pourmand have established that large (~3000 km radius) planetary embryos existed in the solar nebula at the same time that chondrules—millimeter-sized igneous inclusions found in meteorites—were forming. We model the formation of chondrules by passage through bow shocks around such a planetary embryo on an eccentric orbit. We numerically model the hydrodynamics of the flow and find that such large bodies retain an atmosphere with Kelvin-Helmholtz instabilities allowing mixing of this atmosphere with the gas and particles flowing past the embryo. We calculate the trajectories of chondrules flowing past the body and find that they are not accreted by the protoplanet, but may instead flow through volatiles outgassed from the planet's magma ocean. In contrast, chondrules are accreted onto smaller planetesimals. We calculate the thermal histories of chondrules passing through the bow shock. We find that peak temperatures and cooling rates are consistent with the formation of the dominant, porphyritic texture of most chondrules, assuming a modest enhancement above the likely solar nebula average value of chondrule densities (by a factor of 10), attributable to settling of chondrule precursors to the midplane of the disk or turbulent concentration. We calculate the rate at which a planetary embryo's eccentricity is damped and conclude that a single planetary embryo scattered into an eccentric orbit can, over ~105 years, produce ~1024 g of chondrules. In principle, a small number (1-10) of eccentric planetary embryos can melt the observed mass of chondrules in a manner consistent with all known constraints.

  14. Violin Pedagogy and the Physics of the Bowed String

    NASA Astrophysics Data System (ADS)

    McLeod, Alexander Rhodes

    The paper describes the mechanics of violin tone production using non-specialist language, in order to present a scientific understanding of tone production accessible to a broad readership. As well as offering an objective understanding of tone production, this model provides a powerful tool for analyzing the technique of string playing. The interaction between the bow and the string is quite complex. Literature reviewed for this study reveals that scientific investigations have provided important insights into the mechanics of string playing, offering explanations for factors which both contribute to and limit the range of tone colours and dynamics that stringed instruments can produce. Also examined in the literature review are significant works of twentieth century violin pedagogy exploring tone production on the violin, based on the practical experience of generations of teachers and performers. Hermann von Helmholtz described the stick-slip cycle which drives the string in 1863, which replaced earlier ideas about the vibration of violin strings. Later, scientists such as John Schelleng and Lothar Cremer were able to demonstrate how the mechanics of the bow-string interaction can create different tone colours. Recent research by Anders Askenfelt, Knut Guettler, and Erwin Schoonderwaldt have continued to refine earlier research in this area. The writings of Lucien Capet, Leopold Auer, Carl Flesch, Paul Rolland, Kato Havas, Ivan Galamian, and Simon Fischer are examined and analyzed. Each author describes a different approach to tone production on the violin, representing a different understanding of the underlying mechanism. Analyzing these writings within the context of a scientific understanding of tone production makes it possible to compare these approaches more consistently, and to synthesize different concepts drawn from the diverse sources evaluated.

  15. Modeling of the wafer bow in GaN-on-Si epiwafers employing GaN/AlN multilayer buffer structures

    NASA Astrophysics Data System (ADS)

    Miyoshi, Makoto; Watanabe, Arata; Egawa, Takashi

    2016-10-01

    We built a calculation model for the wafer bow in GaN-on-Si epiwafers employing GaN/AlN multilayer (ML) buffer structures by extending Stoney’s equation. The calculated bow and the derived strain in the epilayers were almost consistent with experimental results. The calculation quantitatively revealed that the ML buffers introduced an in-plane compressive stress in the epitaxial structures. Also, relationships between the epiwafer bow and the stress in the respective layers became clear to a certain extent. For instance, when considering the case where periodic structures with 20 nm thick GaN/5 nm thick AlN pairs were grown as ML buffers on 4-in.-diameter and 525 μm thick Si (111) substrates at a growth temperature (T g) of 1125 °C, the stress in the MLs was derived to be 2.18 GPa in the in-plane compressive direction in the GaN layers and 5.89 GPa in the in-plane tensile direction in the AlN layers at T g. Although magnitude of the in-plane stress in the GaN layers is obviously smaller than that in the AlN layers, the restoring force generated in the GaN layers becomes larger than that in the AlN layers, because the force is in proportion to the layer thickness rather than to just the stress. As a consequence, the generated stress in the MLs was considered to produce enough force to suppress the epiwafer bow. The calculation also demonstrated that GaN epilayers on GaN/AlN MLs were strained in the in-plane compressive direction at T g and almost strain-free at room temperature.

  16. Acute plastic bowing of the forearm in adults: a report of two cases.

    PubMed

    Tada, K; Ikeda, K; Tsubouchi, H; Tomita, K

    2008-08-01

    We report 2 adult cases where the diagnosis of acute plastic bowing of the forearm was either delayed or missed. In a 21-year-old man, ulnar bowing was missed and fixation was not performed because the patient had no limitation to his range of movement or pain. In a 24-year-old woman, the presentation of bowing in both the ulna and radius was delayed and corrective osteotomy was necessary for restoration of full range of movement. Prompt diagnosis enables manual reposition for easy restoration of full range of movement. PMID:18725680

  17. A review of orthodontic face-bow injuries and safety equipment.

    PubMed

    Samuels, R H

    1996-09-01

    Reports of soft tissue injuries from orthodontic face-bows have continued to appear in the dental and medical publications since the American Association of Orthodontists reported problems in 1975. In 1994 the results of a preliminary survey of face-bow injuries of the orthodontic societies and dental schools in Europe recorded nine serious injuries. The results of a recent face-bow injury survey of orthodontic practitioners in the United Kingdom and Eire recorded 33. The relative effectiveness of current extraoral traction safety products is discussed in relation to the cause of these continuing injuries.

  18. Lysine directed cross-linking of viral DNA-RNA:DNA hybrid substrate to the isolated RNase H domain of HIV-1 reverse transcriptase.

    PubMed

    Guaitiao, Juan P; Zúñiga, Roberto A; Roth, Monica J; Leon, Oscar

    2004-02-10

    An isolated ribonuclease H domain of HIV-1 reverse transcriptase is capable of specifically removing the tRNA primer within an oligonucleotide mimic. The determinants for substrate specificity are located in a region within the terminal octanucleotide of the acceptor stem of the tRNA. Recognition of the substrate by HIV-1 RNase H was analyzed by the introduction of a cross-linking reagent directed toward lysines on the thymine residue complementary to the scissile bond, facing the major groove of the DNA-RNA:DNA substrate. Cross-linking of the modified substrate to RNase H required the presence of Mn(2+). The Mn(2+) titration of cross-linking paralleled the Mn(2+) requirement for activity. Modified substrate quenched with glycine prior to binding of substrate was efficiently cleaved, whereas the RNA within the cross-linked product was intact. Tryptic digestion of the isolated RNase H-nucleic acid covalent complex revealed a main cross-linked peptide whose N-terminal peptide sequence is VVTLTDTTNQ, indicating that the cross-linked lysine corresponds to Lys476. Cross-linking to K476 was confirmed by analysis of K476C RNase H. Mutation of K476C disrupted the chemical cross-linking while maintaining activity. On the basis of the size of the cross-linker arm, the results indicate that K476 is in closer proximity to the tRNA mimic substrate within the isolated RNase H domain than observed for the RNase H-resistant polypurine tract (PPT) substrate within the HIV-1 RT.

  19. Characterization of Newcastle disease virus isolates by reverse transcription PCR coupled to direct nucleotide sequencing and development of sequence database for pathotype prediction and molecular epidemiological analysis.

    PubMed Central

    Seal, B S; King, D J; Bennett, J D

    1995-01-01

    Degenerate oligonucleotide primers were synthesized to amplify nucleotide sequences from portions of the fusion protein and matrix protein genes of Newcastle disease virus (NDV) genomic RNA that could be used diagnostically. These primers were used in a single-tube reverse transcription PCR of NDV genomic RNA coupled to direct nucleotide sequencing of the amplified product to characterize more than 30 NDV isolates. In agreement with previous reports, differences in the fusion protein cleavage sequence that correlated genotypically with virulence among various NDV pathotypes were detected. By using sequences generated from the matrix protein gene coding for the nuclear localization signal, lentogenic viruses were again grouped phylogenetically separate from other pathotypes. These techniques were applied to compare neurotropic velogenic viruses isolated from an outbreak of Newcastle disease in cormorants and turkeys. Cormorant NDV isolates and an NDV isolate from an infected turkey flock in North Dakota had the fusion protein cleavage sequence 109SRGRRQKRFVG119. The R-for-G substitution at position 110 may be unique for the cormorant-type isolates. Although the amino acid sequences from the fusion protein cleavage site were identical, nucleotide sequence data correlate the outbreak in turkeys to a cormorant virus isolate from Minnesota and not to a cormorant virus isolate from Michigan. On the basis of sequence information, the cormorant isolates are virulent viruses related to isolates of psittacine origin, possibly genotypically distinct from other velogenic NDV isolates. These techniques can be used reliably for Newcastle disease epidemiology and for prediction of pathotypes of NDV isolates without traditional live-bird inoculations. PMID:8567895

  20. Fiber-Based Measurement of Bow-Shock Spectra for Reentry Flight Testing

    NASA Technical Reports Server (NTRS)

    Schott, Timothy D.; Herring, Gregory C.; Munk, Michelle M.; Grinstead, Jay H.; Prabbu, Dinesh K.

    2010-01-01

    We demonstrated a fiber-based approach for obtaining optical spectra of a glowing bow shock in a high-enthalpy air flow. The work was performed in a ground test with the NASA Ames Aerodynamic Heating Facility (AHF) that is used for atmospheric reentry simulation. The method uses a commercial fiber optic that is embedded in the nose of an ablating bluntbody model and provides a line-of-sight view in the streamwise direction - directly upstream into the hot post-shock gas flow. Both phenolic impregnated carbon ablator (PICA) and phenolic carbon (PhenCarb 28) materials were used as thermal protection systems. Results show that the fibers survive the intense heat and operate sufficiently well during the first several seconds of a typical AHF run (20 MJ/kg). This approach allowed the acquisition of optical spectra, enabling a Boltzmann-based electronic excitation temperature measurement from Cu atom impurities (averaged over a line-of-sight through the gas cap, with a 0.04 sec integration time).

  1. Energetic ions upstream of the earth's bow shock during an energetic storm particle event

    NASA Technical Reports Server (NTRS)

    Scholer, M.; Ipavich, F. M.

    1983-01-01

    Simultaneous observations of low-energy protons and alpha particles from ISEE 3 far upstream and from ISEE 1 close to the earth's bow shock during the passage of an interplanetary shock wave with its associated energetic storm particles are presented. Intensities, spectra, and anisotropies of the energetic storm particles are modified due to the interaction of these particles with the earth's bow shock. An intensity spike observed at ISEE 1 during the passage of the interplanetary shock is interpreted as being due to postacceleration of energetic storm particles at the bow shock by the first-order Fermi mechanism. The spikes observed at ISEE 1 after the passage of the interplanetary shock are most probably due to reflection of the energetic storm particles at the bow shock.

  2. Solar wind flow about the terrestrial planets. I - Modeling bow shock position and shape

    NASA Astrophysics Data System (ADS)

    Slavin, J. A.; Holzer, R. E.

    1981-12-01

    A three-parameter method for modeling the position and shape of planetary bow waves was chosen to model the near portion of the Venus, earth and Mars bow shocks, and its results were compared with those of models using one to six free variables. It was found that the relative effective shapes of the near Martian, Cytherean, and terrestrial bow shocks are ellipsoidal, paraboloidal, and hyperboloidal, respectively, in response to the increasing bluntness of the obstacles that the planets present to the solar wind. No significant deviations from axial symmetry were found when the near bow waves of the earth and Venus were mapped into the aberrated terminator plane, in agreement with gas dynamic theory predictions neglecting the effects of the IMF because of their minuteness.

  3. 3/4 VIEW OF STARBOARD SIDE AND BOW AFTER LIFTING FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3/4 VIEW OF STARBOARD SIDE AND BOW AFTER LIFTING FROM WATER. RAILS AND CARRIAGE ON LIFT PLATFORM CAN BE SEEN UNDER SHIP. - U.S. Coast Guard Cutter TANEY, Pier 5, Pratt Street, Baltimore, Independent City, MD

  4. Acute plastic bowing of the radius with a distal radioulnar joint injury: a case report.

    PubMed

    Uehara, Masashi; Yamazaki, Hiroshi; Kato, Hiroyuki

    2010-01-01

    Acute plastic bowing is an incomplete fracture with a deformation that shows no obvious macroscopic fracture line or cortical discontinuity. Although cases of acute plastic bowing of the ulna with a dislocation of the radial head have been previously reported, we present here a rare case of acute plastic bowing of the radius with a distal radioulnar joint injury in a 16-year-old boy. Internal fixation of the detached fragment to the ulnar styloid and repair of the triangular fibrocartilagenous complex resulted in the disappearance of wrist pain. In cases of distal radioulnar joint injuries in children or adolescents, radiographs of the entire forearm should be taken to evaluate the existence of radial bowing. PMID:21089197

  5. A case of neurilemmoma in the infratemporal fossa showing the antral bowing sign.

    PubMed

    Shinohara, Y; Uchida, A; Hiromatsu, T; Hida, K; Kikuta, T

    1993-11-01

    A case is reported of a neurilemmoma which arose in the right infratemporal fossa of a 23-year-old male. A benign tumour was suspected when bowing of the posterior maxillary antral wall was observed on CT. PMID:8181651

  6. Christmas bow pins: a potential inhaled foreign body made safer by industrial modifications.

    PubMed

    Siegel, L G; Mendenhall, H V; Liston, S L

    1981-01-01

    The 3M Company (Minnesota Mining and Manufacturing Company) has produced about three billion plastic Christmas bow pins over 20 years. When it was reported that inhalation of these pins had resulted in two deaths, the company sought otolaryngologic consultation to suggest design modifications which would decrease the risk of aspiration asphyxia. The circular base of the bow pin was modified into the form of a cross so that it would not completely obstruct the airway. Barium was added to render the bow pin radiopaque. When the unmodified bow pin was inserted into the larynx of ten cats, six died. The modified pin caused no deaths in nine cats. We regard this as an example of responsible cooperation between industry and medicine.

  7. Coupling of newborn ions to the solar wind by electromagnetic instabilities and their interaction with the bow shock

    NASA Technical Reports Server (NTRS)

    Winske, D.; Wu, C. S.; Li, Y. Y.; Mou, Z. Z.; Guo, S. Y.

    1985-01-01

    The process by which the solar wind assimilates newly ionized atoms is important for understanding the presence of planetary or interstellar helium in the solar wind, the dynamics of the Active Magnetospheric Particle Tracer Explorers (AMPTE) lithium releases in front of the earth's bow shock, and the formation of cometary tails. In this paper is examined how newborn ions can be coupled to the solar wind in the direction parallel to the magnetic field by means of electromagnetic instabilities driven by the distribution of newborn ions. The linear properties of three instabilities are analyzed and compared with numerical solutions of the linear dispersion equation, while their nonlinear behavior is followed by means of computer simulation to obtain the characteristic time for the pickup process. With a primary emphasis on the AMPTE lithiuim releases, various degrees of realism are introduced into the calculations to model the upstream conditions and the intersection of the lithium with the bow shock. It is shown that a time-dependent shock model is needed to correctly reproduce the amount of lithium which is transmitted through the shock and that the resulting lithium ion distribution is still likely to be subject to the same type of instabilities in the magnetosheath. Applications of these results to comets, in particular the artificial comet expected to be generated by the AMPTE barium release in the magnetosheath, is also briefly discussed.

  8. Coupling of Newborn ions to the solar wind by electromagnetic instabilities and their interaction with the bow shcok

    SciTech Connect

    Winske, D.; Wu, C.S.; Li, Y.Y.; Mou, Z.Z.; Guo, S.Y.

    1985-03-01

    The process by which the solar wind assimilates newly ionized atoms is important for understanding the presence of planetary or interstellar helium in the solar wind, the dynamics of the Active Magnetospheric Particle Tracer Explorers (AMPTE) lithium releases in front of the earth's bow shock, and the formation of cometary tails. In this paper we examine how newborn ions can be coupled to the solar wind in the direction parallel to the magnetic field by means of electromagnetic instabilities driven by the distribution of newborn ions. The linear properties of three instabilities are analyzed and compared with numerical solutions of the linear dispersion equation, while their nonlinear behavior is followed by means of computer simulation to obtain the characteristic time for the pickup process. With a primary emphasis on the AMPTE lithium releases, various degrees of realism are introduced into the calculations to model the upstream conditions and the intersection of the lithium with the bow shcok. It is shown that a time-dependent shock model is needed to correctly reproduce the amount of lithium which is transmitted through the shock and that the resulting lithium ion distribution is still likely to be subject to the same type of instabilities in the magnetosheath. Application of these results to comets, in particular the artificial comet expected to be generated by the AMPTE barium release in the magnetosheath, is also briefly discussed.

  9. Coupling of newborn ions to the solar wind by electromagnetic instabilities and their interaction with the bow shock

    NASA Astrophysics Data System (ADS)

    Winske, D.; Wu, C. S.; Li, Y. Y.; Mou, Z. Z.; Guo, S. Y.

    1985-03-01

    The process by which the solar wind assimilates newly ionized atoms is important for understanding the presence of planetary or interstellar helium in the solar wind, the dynamics of the Active Magnetospheric Particle Tracer Explorers (AMPTE) lithium releases in front of the earth's bow shock, and the formation of cometary tails. In this paper is examined how newborn ions can be coupled to the solar wind in the direction parallel to the magnetic field by means of electromagnetic instabilities driven by the distribution of newborn ions. The linear properties of three instabilities are analyzed and compared with numerical solutions of the linear dispersion equation, while their nonlinear behavior is followed by means of computer simulation to obtain the characteristic time for the pickup process. With a primary emphasis on the AMPTE lithiuim releases, various degrees of realism are introduced into the calculations to model the upstream conditions and the intersection of the lithium with the bow shock. It is shown that a time-dependent shock model is needed to correctly reproduce the amount of lithium which is transmitted through the shock and that the resulting lithium ion distribution is still likely to be subject to the same type of instabilities in the magnetosheath. Applications of these results to comets, in particular the artificial comet expected to be generated by the AMPTE barium release in the magnetosheath, is also briefly discussed.

  10. RADIO SYNCHROTRON EMISSION FROM A BOW SHOCK AROUND THE GAS CLOUD G2 HEADING TOWARD THE GALACTIC CENTER

    SciTech Connect

    Narayan, Ramesh; Sironi, Lorenzo; Oezel, Feryal

    2012-10-01

    A dense ionized cloud of gas has been recently discovered to be moving directly toward the supermassive black hole, Sgr A*, at the Galactic center. In 2013 June, at the pericenter of its highly eccentric orbit, the cloud will be approximately 3100 Schwarzschild radii from the black hole and will move supersonically through the ambient hot gas with a velocity of v{sub p} Almost-Equal-To 5400 km s{sup -1}. A bow shock is likely to form in front of the cloud and could accelerate electrons to relativistic energies. We estimate via particle-in-cell simulations the energy distribution of the accelerated electrons and show that the non-thermal synchrotron emission from these electrons might exceed the quiescent radio emission from Sgr A* by a factor of several. The enhanced radio emission should be detectable at GHz and higher frequencies around the time of pericentric passage and in the following months. The bow shock emission is expected to be displaced from the quiescent radio emission of Sgr A* by {approx}33 mas. Interferometric observations could resolve potential changes in the radio image of Sgr A* at wavelengths {approx}< 6 cm.

  11. The solar cycle dependence of the location and shape of the Venus bow shock

    NASA Technical Reports Server (NTRS)

    Zhang, T.-L.; Luhmann, J. G.; Russell, C. T.

    1990-01-01

    The Venus terminator bow shock position is monitored and it is shown that the shock radius increases as the solar cycle approaches a new maximum. It is also shown that the subsolar bow shock changes with the solar cycle, and that these positions are correlated with each other and with solar activity. It is hypothesized that, at solar minimum, the magnetic barrier is weak, and that some absorption of solar wind is to be expected.

  12. On the observability of bow shocks of Galactic runaway OB stars

    NASA Astrophysics Data System (ADS)

    Meyer, D. M.-A.; van Marle, A.-J.; Kuiper, R.; Kley, W.

    2016-06-01

    Massive stars that have been ejected from their parent cluster and supersonically sailing away through the interstellar medium (ISM) are classified as exiled. They generate circumstellar bow-shock nebulae that can be observed. We present two-dimensional, axisymmetric hydrodynamical simulations of a representative sample of stellar wind bow shocks from Galactic OB stars in an ambient medium of densities ranging from nISM = 0.01 up to 10.0 cm- 3. Independently of their location in the Galaxy, we confirm that the infrared is the most appropriated waveband to search for bow shocks from massive stars. Their spectral energy distribution is the convenient tool to analyse them since their emission does not depend on the temporary effects which could affect unstable, thin-shelled bow shocks. Our numerical models of Galactic bow shocks generated by high-mass ( ≈ 40 M⊙) runaway stars yield H α fluxes which could be observed by facilities such as the SuperCOSMOS H-Alpha Survey. The brightest bow-shock nebulae are produced in the denser regions of the ISM. We predict that bow shocks in the field observed at H α by means of Rayleigh-sensitive facilities are formed around stars of initial mass larger than about 20 M⊙. Our models of bow shocks from OB stars have the emission maximum in the wavelength range 3 ≤ λ ≤ 50 μm which can be up to several orders of magnitude brighter than the runaway stars themselves, particularly for stars of initial mass larger than 20 M⊙.

  13. The Intriguing Giant Bow Shocks near HH 131

    NASA Astrophysics Data System (ADS)

    Wang, Min; Noumaru, Junichi; Wang, Hongchi; Yang, Ji; Chen, Jiansheng

    2005-12-01

    Using the High Dispersion Spectrograph (HDS) at the Subaru Telescope, echelle spectra of two giant arcs, i.e., nebulosities Cw and L associated with HH 131 in Orion are presented. Typical emission lines of Herbig-Haro (HH) objects have been detected toward nebulosity Cw with the broadband filter KV 408. With the low-dispersion spectrograph at the National Astronomical Observatories (NAO) 2.16 m telescope, spectra of nebulosities C, L, and K are obtained, which also show strong [S II] λ6717/λ6731, Hα, and [N II] λ6583 emission lines. Position-velocity distributions of Cw and L are analyzed from the long-slit spectra observed with the HDS Hα narrowband filter. The fastest radial velocity of Cw is Vr~-18.0 km s-1. When the flow at L goes to the south, it slows down. The fastest radial velocity of L has been observed at -45.0 km s-1, and the slowest value is about -18.3 km s-1 the radial velocity gradient is about 200 km s-1 pc-1. The similarity of the fastest radial velocity of Cw to the slowest value of L and their positional connection indicate that they are physically associated. There is a tendency for the entire flow to become less excited and less ionized when going further to the south (i.e., from nebulosities K to L and C), where the most extended (and presumably evolved) objects are seen. The electron densities of all the observed nebulosities are low (ne~102 cm-3). Double-peaked kinematic signatures have been found in Cw from its [N II] λ6583 profiles, while the observed Hα profiles of Cw are almost symmetric. Bow shock models appear to agree with the observed position-velocity diagrams of the [N II] spectra better than Hα spectra, and a bow shock with its wing, apex, and postshock has been possibly revealed near Cw from the [N II] emission. With the suggestion that these arcs are HH shocks possibly ejected out of the Orion A molecular cloud by an uncertain source, their spectra show low to intermediate excitation from their diagnostic line ratios

  14. MESSENGER observations of Mercury's bow shock and magnetopause

    NASA Astrophysics Data System (ADS)

    Slavin, J. A.; Acuña, M. H.; Anderson, B. J.; Benna, M.; Gloeckler, G.; Krimigis, S. M.; Raines, J. M.; Schriver, D.; Trávníček, P.; Zurbuchen, T. H.

    2008-09-01

    Abstract The MESSENGER spacecraft made the first of three flybys of Mercury on January 14, 2008 (1). New observations of solar wind interaction with Mercury were made with MESSENGER's Magnetometer (MAG) (2,3) and Energetic Particle and Plasma Spectrometer (EPPS) - composed of the Energetic Particle Spectrometer (EPS) and Fast Imaging Plasma Spectrometer (FIPS) (3,4). These MESSENGER observations show that Mercury's magnetosphere has a large-scale structure that is distinctly Earth-like, but it is immersed in a comet-like cloud of planetary ions [5]. Fig. 1 provides a schematic view of the coupled solar wind - magnetosphere - neutral atmosphere - solid planet system at Mercury. Here we present new models of bow shock and magnetopause shape and location that incorporate both the MESSENGER and earlier Mariner 10 measurements of these boundaries. A fast magnetosonic Mach number for the solar wind at Mercury's distance from the Sun of ~ 3 is derived from the shape of the bow shock. This value is consistent with earlier observations at these distances from the Sun by the Helios mission. The shape of Mercury's magnetopause and the thickness of the magnetosheath are found to be similar to that of the Earth, suggesting that the solar wind interaction is dominated by its dipolar magnetic field. MESSENGER measurements near the magnetopause do, however, indicate that internal plasma pressure does contribute to the pressure balance across this boundary. MAG and FIPS measurements are used to estimate the ratio of plasma thermal pressure to magnetic pressure at the dusk flank of the plasma sheet and dawn terminator regions, under the assumption that pressure is balanced across the inbound and outbound magnetopause crossings. To investigate the possible origins of the plasma ions in these regions, we utilize a combination of FIPS measurements and the results of 3-D hybrid [6] and magnetohydrodynamic simulations of the solar wind interaction with Mercury for the upstream conditions

  15. PIC EM Relativistic code is used to simulate the Earth bow shock

    NASA Astrophysics Data System (ADS)

    Baraka, S. M.; Ben-Jaffel, L.

    2011-12-01

    The Earth bow shock is created by the supersonic solar wind flowing onto the geomagnetic field. The front of this shock is curved, standing around the Earth from the dayside. The bow shock is of great interest in space plasma investigation as it contains important physics ranging from kinetic to global scales. Interaction of the supersonic solar wind with Earth magnetosphere (magnetopause) creates fast mode magnetosonic waves that travel back upstream, combine and steepen to form the bow shock wave. The distance to the bow shock is then the sum of the magnetopause distance and the magnetosheath thickness. [Merka and Szabo and references therein] It has been established been well established that the bow shock (and the magnetopause) scales with the solar wind ram pressure Psw[Binsack and Vasyliunas, 1968; Formisano, 1979] . We are trying though to simulate the position of the bow shock by using a modified Tristan PIC EM Relativistic Code. By doing so, we will help the science community to use our model to better understand the shock physics in our geospace.

  16. Asymmetric Outer Bow Length and Cervical Headgear Force System: 3D Analysis Using Finite Element Method

    PubMed Central

    Geramy, Allahyar; Hassanpour, Mehdi; Emadian Razavi, Elham sadat

    2015-01-01

    Objectives: This study sought to assess distal and lateral forces and moments of asymmetric headgears by variable outer bow lengths. Materials and Methods: Four 3D finite element method (FEM) models of a cervical headgear attached to the maxillary first molars were designed in SolidWorks 2010 software and transferred to ANSYS Workbench ver. 11 software. Models contained the first molars, their periodontal ligament (PDL), cancellous and cortical bones, a mesiodistal slice of the maxillae and the headgear. Models were the same except for the outer bow length in headgears. The headgear was symmetric in model 1. In models 2 to 4, the headgears were asymmetric in length with differences of 5mm, 10mm and 15mm, respectively. A 2.5 N force in horizontal plane was applied and the loading manner of each side of the outer bow was calculated trigonometrically using data from a volunteer. Results: The 15mm difference in outer bow length caused the greatest difference in lateral (=0.21 N) and distal (= 1.008 N) forces and also generated moments (5.044 N.mm). Conclusion: As the difference in outer bow length became greater, asymmetric effects increased. Greater distal force in the longer arm side was associated with greater lateral force towards the shorter arm side and more net yawing moment. Clinical Relevance: A difference range of 1mm to 15 mm of length in cervical headgear can be considered as a safe length of outer bow shortening in clinical use. PMID:26622275

  17. Global Explicit Particle-in-cell Simulations of the Nonstationary Bow Shock and Magnetosphere

    NASA Astrophysics Data System (ADS)

    Yang, Zhongwei; Huang, Can; Liu, Ying D.; Parks, George K.; Wang, Rui; Lu, Quanming; Hu, Huidong

    2016-07-01

    We carry out two-dimensional global particle-in-cell simulations of the interaction between the solar wind and a dipole field to study the formation of the bow shock and magnetosphere. A self-reforming bow shock ahead of a dipole field is presented by using relatively high temporal-spatial resolutions. We find that (1) the bow shock and the magnetosphere are formed and reach a quasi-stable state after several ion cyclotron periods, and (2) under the B z southward solar wind condition, the bow shock undergoes a self-reformation for low β i and high M A . Simultaneously, a magnetic reconnection in the magnetotail is found. For high β i and low M A , the shock becomes quasi-stationary, and the magnetotail reconnection disappears. In addition, (3) the magnetopause deflects the magnetosheath plasmas. The sheath particles injected at the quasi-perpendicular region of the bow shock can be convected downstream of an oblique shock region. A fraction of these sheath particles can leak out from the magnetosheath at the wings of the bow shock. Hence, the downstream situation is more complicated than that for a planar shock produced in local simulations.

  18. Primary bowing tremor: a task-specific movement disorder of string instrumentalists.

    PubMed

    Lederman, Richard J

    2012-12-01

    Fear of a tremulous or unsteady bow is widespread among string instrumentalists. Faulty technique and performance anxiety have generally been blamed. The cases of 4 high-level violinists and 1 violist, 3 women and 2 men, with uncontrollable bow tremor are presented. Age at onset was from 16 to 75 years, and symptom duration 8 months to 20 years at the time of neurological evaluation. The degree of tremor varied with type of bow stroke and even the portion of the bow contacting the string. Only 1 patient had a slight postural tremor of the opposite limb. In 3 of 5 the tremor was task-specific; the other 2 had mild and nontroubling tremor with other activities. The tremor appeared to worsen over time but then seemed to stabilize. The characteristics of this tremor appear to be distinguishable from the features of both essential tremor and focal dystonia; comparison is made with representative string players afflicted by these other disorders. Analogy of this tremor is made with primary writing tremor, a well-defined task-specific movement disorder also sharing at least some features with both essential tremor and writers' cramp, a focal dystonia. Hence, it was decided to call this primary bowing tremor. Clinical features, family history, diagnostic studies, and responsiveness to treatment of primary writing tremor are discussed to emphasize the similarity to primary bowing tremor. This appears to represent a previously unreported form of task-specific movement disorder of string instrumentalists.

  19. Direct method for determination of Sudan I in FD&C Yellow No. 6 and D&C Orange No. 4 by reversed-phase liquid chromatography.

    PubMed

    Petigara, Bhakti R; Scher, Alan L

    2007-01-01

    A reversed-phase liquid chromatographic method was developed to determine parts-per-million and higher levels of Sudan 1, 1-(phenylazo)-2-naphthalenol, in the disulfo monoazo color additive FD&C Yellow No. 6 and in a related monosulfo monoazo color additive, D&C Orange No. 4. Sudan I, the corresponding unsulfonated monoazo dye, is a known impurity in these color additives. The color additives are dissolved in water and methanol, and the filtered solutions are directly chromatographed, without extraction or concentration, by using gradient elution at 0.25 mL/min. Calibrations from peak areas at 485 nm were linear. At a 99% confidence level, the limits of determination were 0.008 microg Sudan I/mL (0.4 ppm) in FD&C Yellow No. 6 and 0.011 microg Sudan I/mL (0.00011%) in D&C Orange No. 4. The confidence intervals were 0.202 +/- 0.002 microg Sudan I/mL (10.1 +/- 0.1 ppm) near the specification level for Sudan I in FD&C Yellow No. 6 and 20.0 +/- 0.2 microg Sudan I/mL (0.200 +/- 0.002%) near the highest concentration of Sudan I found in D&C Orange No. 4. A survey was conducted to determine Sudan I in 28 samples of FD&C Yellow No. 6 from 17 international manufacturers over 3 years, and in a pharmacology-tested sample. These samples were found to contain undetected levels (16 samples), 0.5-9.7 ppm Sudan I (0.01-0.194 microg Sudan I/mL in analyzed solutions; 11 samples including the pharmacology sample), and > or =10 ppm Sudan I (> or = 0.2 microg Sudan I/mL; 2 samples). Analyses of 21 samples of D&C Orange No. 4 from 8 international manufacturers over 4 years found Sudan I at undetected levels (8 samples), 0.0005 to < 0.005% Sudan I (0.05 to < 0.5 microg Sudan I/mL in analyzed solutions; 3 samples, including a pharmacology batch), 0.005 to <0.05% Sudan I (0.5 to <5 microg Sudan I/mL; 9 samples), and 0.18% Sudan I (18 microg Sudan I/mL; 1 sample).

  20. Whistler waves associated with the Uranian bow shock - Outbound observations

    NASA Technical Reports Server (NTRS)

    Smith, Charles W.; Wong, Hung K.; Goldstein, Melvyn L.

    1991-01-01

    High-resolution magnetic field measurements from the first outbound crossing of the Uranian bowshock by the Voyager 2 spacecraft between January 27 and 30, 1986, are examined. Evidence is found of enhanced whistler wave activity in the vicinity of three shock crossings but little or no evidence of such activity elsewhere. Two wave events display two separate and simultaneous wave enhancements each. From an investigation of these events using high-resolution field data, it is concluded that they are analogous to those whistler waves upstream of the earth's bow shock that are driven by beams of electrons. An instability analysis is presented to show that a single electron beam with reasonable parameters can penetrate both of the upstream and downstream of a shock crossing. This event displays only one relatively broad spectral enhancement in the same frequency regime and is left-hand polarized in the spacecraft frame. It is argued that this event is the result of a gyrating proton distribution associated with the oblique shock.

  1. Whistler wave bursts upstream of the Uranian bow shock

    NASA Technical Reports Server (NTRS)

    Smith, Charles W.; Goldstein, Melvyn L.; Wong, Hung K.

    1989-01-01

    Observations of magnetic field wave bursts upstream of the Uranian bow shock are reported which were recorded prior to the inbound shock crossing. Three wave types are identified. One exhibits a broad spectral enhancement from a few millihertz to about 50 mHz and is seen from 17 to 10 hr prior to the inbound shock crossing. It is argued that these waves are whistler waves that have propagated upstream from the shock. A second wave type has a spacecraft frame frequency between 20 and 40 mHz, is seen only within or immediately upstream of the shock pedestal, is right-hand polarized in the spacecraft frame, and has a typical burst duration of 90 s. The third wave type has a spacecraft frame frequency of about 0.15 Hz, is seen exclusively within the shock pedestal, is left-hand polarized in the spacecraft frame, and has a burst duration lasting up to 4 min. It is argued that the low-frequency bursts are whistler waves with phase speed comparable to, but in excess of, the solar wind speed.

  2. Magnetohydrodynamic and gasdynamic theories for planetary bow waves

    NASA Technical Reports Server (NTRS)

    Spreiter, J. R.; Stahara, S. S.

    1984-01-01

    The observed properties of bow waves and the associated plasma flows are outlined, along with those features identified that can be described by a continuum magnetohydrodynamic flow theory as opposed to a more detailed multicomponent particle and field plasma theory. The primary objectives are to provide an account of the fundamental concepts and current status of the magnetohydrodynamic and gas dynamic theories for solar wind flow past planetary bodies. This includes a critical examination of: (1) the fundamental assumptions of the theories; (2) the various simplifying approximations introduced to obtain tractable mathematical problems; (3) the limitations they impose on the results; and (4) the relationship between the results of the simpler gas dynamic-frozen field theory and the more accurate but less completely worked out magnetohydrodynamic theory. Representative results of the various theories are presented and compared. A number of deficiencies, ambiguities, and suggestions for improvements are discussed, and several significant extensions of the theory required to provide comparable results for all planets, their satellites, and comets are noted.

  3. Multi-Spacecraft Investigation of Terrestrial Bow Shock: Cluster Observations

    NASA Astrophysics Data System (ADS)

    Kruparova, O.; Krupar, V.; Santolik, O.; Soucek, J.; Safrankova, J.; Nemecek, Z.; Nemec, F.; Maksimovic, M.

    2015-12-01

    Due to the interaction of the solar wind with the Earth's magnetosphere, a permanent collisionless bow shock (BS) is formed in front of the nose of the magnetopause. We investigate a large number of BS crossings observed by the Cluster spacecraft between years 2001 and 2015. The FGM instruments provide us with magnetic field measurements sampled at 22 Hz, which is sufficient for a precise identification of BS crossings. We compare observed BS locations with distances predicted by gas dynamical models based on upstream plasma parameters in the solar wind. We achieve a very good agreement in a case of a paraboloid with the Earth fixed in a focus point. We use a simple timing method for the estimation of a BS normal and velocity along this normal. We found that the deviations of calculated BS normals from the paraboloid shape are within 20 degrees. We compare calculated BS velocities with several upstream parameters. We also investigate BS ramp thickness which is comparable to the Larmor radius in the case of quasi-perpendicular BS crossings.

  4. Progressive deformation of slaty cleavage in the Broken Bow uplift, Oklahoma

    SciTech Connect

    Yang, Qingming; Nielsen, K.C. )

    1992-01-01

    The oldest rocks of the Ouachita Mountains are exposed in the Broken Bow uplift of OK. These low grade metasedimentary rocks reveal a polyphase deformational history in which folded cleavages are recorded. On a microscopic scale, zones of pressure solution residuals (PSR) consisting of mica, iron oxides, and other insoluble opaque materials are aligned parallel to the cleavage traces. Evaluation of the PSR has revealed two distinct morphologies: one high frequency spacing of narrow PSR and one low frequency spacing of broader PSR. Age relationships are difficult to establish; however, the low frequency spacing may be younger based on a few cross cutting relations. The slaty cleavage is folded and is rotated from regional northerly dip to a local southerly dip. These synforms are coaxial with the first generation folds and commonly are truncated by reverse faults on the south dipping limbs. Flattening on these south dipping limbs is apparent in the recumbent buckles; slip on favorable oriented PSR; and the development of local subhorizontal rough cleavage in the sandstones and siltstones as well as pencil structures in the finer grained rocks. Using the SEM, weakly developed fabrics can be seen in these fragments: the original bedding, slaty cleavage (1--3[mu]m PSR), and a third fabric oriented 15--20[degree] to the slaty cleavage. This flattening fabric appears to modify the slaty cleavage by reorienting the micaceous minerals in the PSR and locally truncating and reorienting the PSR. As a result, field observations of cleavage orientation reveal an upper limit to the southerly dipping slaty cleavage of 50--60[degree]. Subsequently, the slaty cleavage is poorly developed, but has a more gentle dip approaching that of the rough cleavage.

  5. The Interaction of Solar wind Discontinuities with the Earth's Bow Shock

    NASA Technical Reports Server (NTRS)

    Sibeck, David G.

    2000-01-01

    Funding from NASA Grant No. NAG54679 was received in three installments. The first year's installment amounted to only one month of salary support and was used to prepare survey plots. The second year's installment allowed us to complete two research papers concerning the interaction of solar wind discontinuities with the Earth's bow shock. In the first (published) paper, we reported that the discontinuities launch slow mode waves into the magnetosheath and the slow mode waves always propagate antisunward through the flank magnetosheath. Because the sunward/antisunward sense of the magnetosheath magnetic field reverses across local noon, so does the (north/south or east/west) sense of the velocity fluctuations associated with the waves. Wind, Geotail, and IMP-8 observations were used for this study. In the second study, we used Wind and Interball-1 observations to demonstrate that pressure pulses in the magnetosheath occur in pairs and that they bound pressure cavities and/or brief intervals of outward magnetopause motion. This paper is now in press. Funding from the third year's installment has been used to investigate the two aspects of the foreshock. Two manuscripts are now in preparation for submission to the Journal of Geophysical Research. The first reports that waves within the foreshock account for many instances of poor correlations between two solar wind monitors. Remaining cases of poor correlation occur during intervals of nearly constant IMF orientations and magnetic field strengths. While the former category pose a significant difficulty for space weather forecasts, the latter do not. The second study surveys IMP-8 observations of the foreshock. We find that diamagnetic cavities are common, particularly during periods of high solar wind velocity and low solar wind density. Plasma densities, temperatures, and magnetic field strengths fall during intervals of enhanced energetic particle fluxes. The cavities are bounded by regions of decelerated solar

  6. Reversible dementias

    PubMed Central

    Tripathi, Manjari; Vibha, Deepti

    2009-01-01

    In recent years, more attention has been given to the early diagnostic evaluation of patients with dementia which is essential to identify patients with cognitive symptoms who may have treatable conditions. Guidelines suggest that all patients presenting with dementia or cognitive symptoms should be evaluated with a range of laboratory tests, and with structural brain imaging with computed tomography (CT) or magnetic resonance imaging (MRI). While many of the disorders reported as ‘reversible dementias’ are conditions that may well be associated with cognitive or behavioral symptoms, these symptoms are not always sufficiently severe to fulfill the clinical criteria for dementia. Thus, while the etiology of a condition may be treatable it should not be assumed that the associated dementia is fully reversible. Potentially reversible dementias should be identified and treatment considered, even if the symptoms are not sufficiently severe to meet the clinical criteria for dementia, and even if partial or full reversal of the cognitive symptoms cannot be guaranteed. In the literature, the most frequently observed potentially reversible conditions identified in patients with cognitive impairment or dementia are depression, adverse effects of drugs, drug or alcohol abuse, space-occupying lesions, normal pressure hydrocephalus, and metabolic conditions land endocrinal conditions like hypothyroidism and nutritional conditions like vitamin B-12 deficiency. Depression is by far the most common of the potentially reversible conditions. The review, hence addresses the common causes of reversible dementia and the studies published so far. PMID:21416018

  7. Particle injection and acceleration at earth's bow shock - Comparison of upstream and downstream events

    NASA Technical Reports Server (NTRS)

    Ellison, Donald C.; Moebius, Eberhard; Paschmann, Goetz

    1990-01-01

    The injection and acceleration of thermal solar wind ions at the quasi-parallel earth's bow shock during radial interplanetary magnetic field conditions is investigated. Active Magnetospheric Particle Tracer Explorers/Ion Release Module satellite observations of complete proton spectra, and of heavy ion spectra above 10 keV/Q, made on September 12, 1984 near the nose of the shock, are presented and compared to the predictions of a Monte Carlo shock simulation which includes diffusive shock acceleration. It is found that the spectral observations are in good agreement with the predictions of the simulation when it is assumed that all accelerated ions originate in the solar wind and are injected into the acceleration mechanism by thermal leakage from the downstream plasma. The efficiency, which is determined directly from the downstream observations, is high, with at least 15 percent of the solar wind energy flux going into accelerated particles. The comparisons allow constraints to be placed on the rigidity dependence of the scattering mean free path and suggest that the upstream solar wind must be slowed substantially by backstreaming accelerated ions prior to undergoing a sharp transition in the viscous subshock.

  8. Inversion of absorption anisotropy and bowing of crystal field splitting in wurtzite MgZnO

    NASA Astrophysics Data System (ADS)

    Neumann, M. D.; Esser, N.; Chauveau, J.-M.; Goldhahn, R.; Feneberg, M.

    2016-05-01

    The anisotropic optical properties of wurtzite MgxZn1-xO thin films (0 ≤x ≤0.45 ) grown on m-plane ZnO substrates by plasma assisted molecular beam epitaxy are studied using spectroscopic ellipsometry at room temperature. The data analysis provides the dielectric functions for electric field polarizations perpendicular and parallel to the optical axis. The splitting between the absorption edges of the two polarization directions decreases between x = 0 and x = 0.24, while an inverted absorption anisotropy is found at higher Mg content, indicating a sign change of the crystal field splitting Δcr as for the spin orbit parameter. The characteristic energies such as exciton binding energies and band gaps are determined from the analysis of the imaginary parts of the dielectric functions. In particular, these data reveal a bowing parameter of b =-283 meV for describing the compositional dependence of the crystal field splitting and indicate Δcr=-327 meV for wurtzite MgO. The inverted valence band ordering of ZnO ( Γ7-Γ9-Γ7 ) is found to be preserved with increasing Mg content, while the optical selection rules interchange.

  9. Theory of 2 omega(sub pe) radiation induced by the bow shock

    NASA Technical Reports Server (NTRS)

    Yoon, Peter H.; Wu, C. S.; Vinas, A. F.-; Reiner, M. J.; Fainberg, J.; Stone, R. G.

    1994-01-01

    A new radiation emission mechanism is proposed to explain electomagnetic radiation observed at twice the electron plasma frequency, 2 omega(sub pe), in the upstream region of the Earth's bow shock. This radiation had its origin at the electron foreshock boundary where energetic electron beams and intense narrow-band Langmiur waves are observed. The proposed emission mechanism results from the interaction of the electron beam and Langmuir waves that are backscattered off thermal ions. This interaction is described by a nonlinear dispersion equation which incorporates an effect owing to electron trajectory modulation by the backscattered Langmuir waves. Subsequent analysis of the dispersion equation reveals two important consequences. First, a long-wavelength electrostatic quasi-mode with frequency at 2 omega(sub pe) is excited, and second, the quasi-mode and the electomagnetic mode are nonlinearly coupled. The implication is that, when the excited 2 omega(sub pe) quasi-mode propagates in an inhomgeneous medium with slightly decreasing density, the quasi-mode can be converted directly into an electromagnetic mode. Hense the electomagnetic radiation at twice the plasma frequency is generated. Numerical solutions of the dispersion equation with the choice of parameters that describe physical characteristics of the electron foreshock are presented, which illustrates the viability of the new mechanism.

  10. Propagation characteristics of young hot flow anomalies near the bow shock: Cluster observations

    NASA Astrophysics Data System (ADS)

    Xiao, T.; Zhang, H.; Shi, Q. Q.; Zong, Q.-G.; Fu, S. Y.; Tian, A. M.; Sun, W. J.; Wang, S.; Parks, G. K.; Yao, S. T.; Rème, H.; Dandouras, I.

    2015-06-01

    Based on Cluster observations, the propagation velocities and normal directions of hot flow anomaly (HFA) boundaries upstream the Earth's bow shock are calculated. Twenty-one young HFAs, which have clear leading and trailing boundaries, were selected, and multispacecraft timing method considering errors was employed for the investigation. According to the difference in the propagation velocity of the leading and trailing edges, we categorized these events into three groups, namely, contracting, expanding, and stable events. The contraction speed is a few tens of kilometers per second for the contracting HFAs, and the expansion speed is tens to more than hundred kilometers per second for expanding events. For the stable events, the leading and trailing edges propagate at almost the same speed within the error range. We have further investigated what causes them to contract, expand, or stay stable by carefully calculating the thermal pressure of the young HFAs which have two distinct ion populations (solar wind beam and reflected flow). It is found that the extreme value of the sum of the magnetic and thermal pressure inside the HFAs compared with that of the nearest point outside of the leading edges is higher for expanding events and lower for contracting events, and there is no significant difference for the stable events, and the total pressure (sum of thermal, magnetic, and dynamic pressure) variation has a significant effect on the evolution for most (70%) of the HFAs, which implies that the pressure plays an important role in the evolution of young HFAs.

  11. Control of initial bow of sapphire substrates for III-nitride epitaxy by internally focused laser processing

    NASA Astrophysics Data System (ADS)

    Aida, Hideo; Aota, Natsuko; Takeda, Hidetoshi; Koyama, Koji

    2012-12-01

    Processing by a laser beam focused within the substrate is used to control the initial bowing of sapphire substrates for III-nitride epitaxy. The process modifies the sapphire crystallinity at and near the focal area from single crystal to an amorphous phase. As volume expansion occurs inside the sapphire, strain is generated and, consequently, changes in the bowing. By controlling the focal depth and process pitch, we demonstrate a ˜250 μm pre-bowed sapphire substrate while only ±15 μm of bowing control is possible with a regular wafering process. We also demonstrate epitaxial growth of III-nitride on the pre-bowed sapphire substrates by metal organic chemical vapor deposition (MOCVD), which suggests an enlargement for the process window for III-nitride epitaxy on sapphire substrate. It is also shown that the pre-bowing by laser treatment functions to improve the crystal quality of grown III-nitride films.

  12. Reversible Sterilization

    ERIC Educational Resources Information Center

    Largey, Gale

    1977-01-01

    Notes that difficult questions arise concerning the use of sterilization for alleged eugenic and euthenic purposes. Thus, how reversible sterilization will be used with relation to the poor, mentally ill, mentally retarded, criminals, and minors, is questioned. (Author/AM)

  13. Reversible Cardiomyopathies

    PubMed Central

    Patel, Harsh; Madanieh, Raef; Kosmas, Constantine E; Vatti, Satya K; Vittorio, Timothy J

    2015-01-01

    Cardiomyopathies (CMs) have many etiological factors that can result in severe structural and functional dysregulation. Fortunately, there are several potentially reversible CMs that are known to improve when the root etiological factor is addressed. In this article, we discuss several of these reversible CMs, including tachycardia-induced, peripartum, inflammatory, hyperthyroidism, Takotsubo, and chronic illness–induced CMs. Our discussion also includes a review on their respective pathophysiology, as well as possible management solutions. PMID:26052233

  14. Yield stress reversibility and the operation of Frank-Read sources in L1{sub 2} alloys in the anomalous regime for (111) slip

    SciTech Connect

    Ezz, S.S.; Hirsch, P.B.

    1995-08-01

    The yield stress {tau}{sub y} at small strains ({approx} 0.01%) is strain rate independent, and has the same anomalous temperature dependence as that of the 0.2% strain. {tau}{sub y} is considered to be the stress at which Frank-Read sources operate in a virgin crystal. For successful operation, {tau}{sub y} must exceed the stress {tau}{sub s}, at which screws propagate dynamically through the crystal and the source dislocation must pass rapidly through the unstable Frank-Read configuration. This can be achieved by the bowing edge dislocation overcoming local obstacles before reaching that configuration. Loops elongated along the screw direction are expected to be formed in the microstrain region. Under certain conditions such loops are unstable on unloading, thereby generating long edge dislocations which can operate successfully as sources at low but not at high temperatures, explaining the reversibility phenomenon.

  15. The upper Bow Island (Blackleaf) Formation of southwestern Alberta: Geological aspects and exploration approaches

    SciTech Connect

    Putnam, P.E.; Christensen, S.L. )

    1991-06-01

    The upper parts of the Bow Island Formation (Albian) of southwestern Alberta are significant gas reservoirs. The main westernmost reservoir zone is part of a complex package of interbedded lenticular sandstones, mudstones, and localized chert pebble conglomerates. The depositional setting for these sediments comprised a wave-dominated shoreline with conglomerates found proximal to drowned river mouths. The coarse nature of the upper Bow Island is related to tectonic movements associated with Crowsnest (Vaughn) volcanism. Conglomerates form the most impressive Bow Island reservoirs because of their thickness (up to 25 m) and petrophysical properties (17% porosity, 24 d permeability). Diagenesis dominantly comprises compaction features within grain-supported conglomerates. Increasing quartz content is related to decreasing grain size and is associated with porosity occlusion by quartz overgrowths. Bow Island reservoirs in southwestern Alberta are cool (under 50C) and significantly underpressured (0.2 psi). The high permeabilities and low pressures at depths of 1,000 to 1,500 m suggest the potential for formation damage is high, and many wells in the region were targeted for deeper, high-pressure zones. In spite of the low pressures, however, many Bow Island wells are capable of excellent gas deliveries with individual well recoveries of up to 10 bcf. All significant Bow Island porosity in the deepest, undisturbed parts of southwestern Alberta is gas saturated with updip aquifers flanking the gas. Seismic definition of the thickest Bow Island targets is feasible but has been hampered, in part, by difficult surface conditions and a prior emphasis on deeper targets.

  16. A bow-shaped thermal structure traveling upstream of the zonal wind flow of Venus atmosphere

    NASA Astrophysics Data System (ADS)

    Taguchi, Makoto; Fukuhara, Tetsuya; Imamura, Takeshi; Kouyama, Toru; Nakamura, Masato; Sato, Takao M.; Ueno, Munetaka; Suzuki, Makoto; Iwagami, Naomoto; Sato, Mitsuteru; Hashimoto, George L.; Takagi, Seiko; Akatsuki Science Team

    2016-10-01

    The Longwave Infrared Camera (LIR) onboard the Japanese Venus orbiter Akatsuki acquires a snap shot of Venus in the middle infrared region, and provides a brightness temperature distribution at the cloud-top altitudes of about 65 km. Hundreds of images taken by LIR have been transferred to the ground since the successful Venus orbit insertion of Akatsuki on Dec. 7, 2015. Here we report that a bow shaped thermal structure extending from the northern high latitudes to the southern high latitudes was found in the brightness temperature map on Dec. 7, 2015, and that it lasted for four days at least surprisingly at almost same geographical position. The bow shape structure looks symmetrical with the equator, and consists of a high temperature region in east or upstream of the background strong westward wind or the super rotation of the Venus atmosphere followed by a low temperature region in west with an amplitude of 5 K. It appeared close to the evening terminator in the dayside, and seems not to have stayed in the same local time rather to have co-rotated with the slowly rotating ground where the western part of Aphrodite Continent was below the center of the bow shape. Meridionally aligned dark filaments similar to the bow shape structure in shape but in much smaller scale were also identified in the brightness temperature map on Dec. 7, and they propagated upstream of the zonal wind as well. The bow shape structure disappeared when LIR observed the same local time and longitude in the earliest opportunity on Jan. 16, 2016. Similar events, though their amplitudes were less than 1 K, were found on Apr. 15 and 26, 2016, but they appeared in different local times and longitudes. A simulation of a gravity wave generated in the lower atmosphere and propagating upward reproduces the observed bow shape structure. The bow shape structure could be a signature of transferring momentum from the ground to the upper atmosphere.

  17. Possible generation mechanisms of low-frequency waves /less than about 50 Hz/ with application to the bow shock plasma

    NASA Technical Reports Server (NTRS)

    Dangelo, N.

    1979-01-01

    Generation mechanisms of waves observed at the earth's bow shock or in its vicinity within the frequency range extending up to about 50 Hz are reviewed. Observations and theories regarding waves in the solar wind upstream of the bow shock (both low-frequency 0.01-0.05 Hz and high-frequency 0.5-4 Hz waves), waves in the bow shock itself and magnetosheath waves arising from processes of generation or amplification in the bow shock are considered. Hydromagnetic, ion-acoustic and whistler type waves are discussed.

  18. A bow shock in front of Ganymede's magnetosphere

    NASA Astrophysics Data System (ADS)

    Jia, X.; Walker, R. J.; Kivelson, M. G.

    Ganymede orbits around Jupiter at nearly 15 Jovian radii close to the equatorial plane of Jupiter Galileo observations indicate that Jupiter s corotational plasma typically is subsonic and subalfv e nic at this distance Therefore a bow shock does not need form in front of Ganymede s magnetosphere We have reexamined Galileo s six encounters with Ganymede and found that during the G8 pass there is a magnetic field magnitude increase sim 10 about two minutes before the first magnetopause crossing associated with a sudden broadband enhancement of the wave power in the Plasma Wave Subsystem PWS data Ganymede was located in the dawn to morning sector of Jupiter s magnetosphere and very close to the center of the Jovian plasma sheet On this pass the plasma density was relatively high compared with the other passes and the corotational flow speed is faster in this sector Krupp et al 2001 Since the total thermal pressure in Jupiter s plasma sheet mostly comes from energetic particles we use the Energetic Particle Detector EPD data to calculate the energetic particle pressure Furthermore we used the radio emission frequency to infer an upper limit of the electron number density By combining these data together we can calculate the possible range of magnetosonic Mach numbers of the background flow Our calculation indicates that the magnetosonic Mach number M ms is between 0 60 and 1 27 This implies that the jump in the magnetic field strength and the sudden enhancement of wave powers are most possibly the signatures of a

  19. REINTERPRETATION OF SLOWDOWN OF SOLAR WIND MEAN VELOCITY IN NONLINEAR STRUCTURES OBSERVED UPSTREAM OF EARTH'S BOW SHOCK

    SciTech Connect

    Parks, G. K.; Lin, N.; Lee, E.; Hong, J.; Fu, S. Y.; McCarthy, M.; Cao, J. B.; Liu, Y.; Shi, J. K.; Goldstein, M. L.; Canu, P.; Dandouras, I.; Reme, H.

    2013-07-10

    Two of the many features associated with nonlinear upstream structures are (1) the solar wind (SW) mean flow slows down and deviates substantially and (2) the temperature of the plasma increases in the structure. In this Letter, we show that the SW beam can be present throughout the entire upstream event maintaining a nearly constant beam velocity and temperature. The decrease of the velocity is due to the appearance of new particles moving in the opposite direction that act against the SW beam and reduce the mean velocity as computed via moments. The new population, which occupies a larger velocity space, also contributes to the second moment, increasing the temperature. The new particles include the reflected SW beam at the bow shock and another population of lower energies, accelerated nearby at the shock or at the boundary of the nonlinear structures.

  20. Acceleration of solar wind ions to 1 MeV by electromagnetic structures upstream of the Earth's bow shock

    NASA Astrophysics Data System (ADS)

    Stasiewicz, K.; Markidis, S.; Eliasson, B.; Strumik, M.; Yamauchi, M.

    2013-05-01

    We present measurements from the ESA/NASA Cluster mission that show in situ acceleration of ions to energies of 1 MeV outside the bow shock. The observed heating can be associated with the presence of electromagnetic structures with strong spatial gradients of the electric field that lead to ion gyro-phase breaking and to the onset of chaos in ion trajectories. It results in rapid, stochastic acceleration of ions in the direction perpendicular to the ambient magnetic field. The electric potential of the structures can be compared to a field of moguls on a ski slope, capable of accelerating and ejecting the fast running skiers out of piste. This mechanism may represent the universal mechanism for perpendicular acceleration and heating of ions in the magnetosphere, the solar corona and in astrophysical plasmas. This is also a basic mechanism that can limit steepening of nonlinear electromagnetic structures at shocks and foreshocks in collisionless plasmas.

  1. Direct Analysis of Reversed-Phase HPTLC Separated Tryptic Protein Digests using a Liquid Microjunction Surface Sampling Probe/ESI-MS System

    SciTech Connect

    Emory, Joshua F; Walworth, Matthew J; Van Berkel, Gary J; Schulz, Michael; Minarik, susanne

    2010-01-01

    The sampling, ionization and detection of tryptic peptides separated in one-dimension on reversed phase HPTLC plates was performed using liquid microjunction surface sampling probe electrospray ionization mass spectrometry. Tryptic digests of five proteins (cytochrome c., myoglobin, beta-casein, lysozyme, and bovine serum albumin) were spotted on reversed phase HPTLC RP-8 F254s and HPTLC RP-18 F254s plates. The plates were then developed using 70/30 methanol/water with 0.1 M ammonium acetate. A dual purpose extraction/electrospray solution containing 70/30/0.1 water/methanol/formic acid was infused through the sampling probe during analysis of the developed lanes. Both full scan mass spectra and data dependent tandem mass spectra were acquired for each development lane to detect and verify the peptide distributions. Data dependent tandem mass spectra provided both protein identification and sequence coverage information. Highest sequence coverages were achieved for cytochrome c. and myoglobin (62.5% and 58.3%, respectively) on reversed phase RP-8 plates. While the tryptic peptides were separated enough for identification, the peptide bands did show some overlap with most peptides located in the lower half of the development lane. Proteins whose peptides were more separated gave higher sequence coverage. Larger proteins such as beta-casein and BSA which were spotted in lower relative amounts gave much lower sequence coverage than the smaller proteins.

  2. BOW SHOCK FRAGMENTATION DRIVEN BY A THERMAL INSTABILITY IN LABORATORY ASTROPHYSICS EXPERIMENTS

    SciTech Connect

    Suzuki-Vidal, F.; Lebedev, S. V.; Pickworth, L. A.; Swadling, G. F.; Skidmore, J.; Hall, G. N.; Bennett, M.; Bland, S. N.; Burdiak, G.; De Grouchy, P.; Music, J.; Suttle, L.; Ciardi, A.; Rodriguez, R.; Gil, J. M.; Espinosa, G.; Hartigan, P.; Hansen, E.; Frank, A.

    2015-12-20

    The role of radiative cooling during the evolution of a bow shock was studied in laboratory-astrophysics experiments that are scalable to bow shocks present in jets from young stellar objects. The laboratory bow shock is formed during the collision of two counterstreaming, supersonic plasma jets produced by an opposing pair of radial foil Z-pinches driven by the current pulse from the MAGPIE pulsed-power generator. The jets have different flow velocities in the laboratory frame, and the experiments are driven over many times the characteristic cooling timescale. The initially smooth bow shock rapidly develops small-scale nonuniformities over temporal and spatial scales that are consistent with a thermal instability triggered by strong radiative cooling in the shock. The growth of these perturbations eventually results in a global fragmentation of the bow shock front. The formation of a thermal instability is supported by analysis of the plasma cooling function calculated for the experimental conditions with the radiative packages ABAKO/RAPCAL.

  3. Bow Shock Fragmentation Driven by a Thermal Instability in Laboratory Astrophysics Experiments

    NASA Astrophysics Data System (ADS)

    Suzuki-Vidal, F.; Lebedev, S. V.; Ciardi, A.; Pickworth, L. A.; Rodriguez, R.; Gil, J. M.; Espinosa, G.; Hartigan, P.; Swadling, G. F.; Skidmore, J.; Hall, G. N.; Bennett, M.; Bland, S. N.; Burdiak, G.; de Grouchy, P.; Music, J.; Suttle, L.; Hansen, E.; Frank, A.

    2015-12-01

    The role of radiative cooling during the evolution of a bow shock was studied in laboratory-astrophysics experiments that are scalable to bow shocks present in jets from young stellar objects. The laboratory bow shock is formed during the collision of two counterstreaming, supersonic plasma jets produced by an opposing pair of radial foil Z-pinches driven by the current pulse from the MAGPIE pulsed-power generator. The jets have different flow velocities in the laboratory frame, and the experiments are driven over many times the characteristic cooling timescale. The initially smooth bow shock rapidly develops small-scale nonuniformities over temporal and spatial scales that are consistent with a thermal instability triggered by strong radiative cooling in the shock. The growth of these perturbations eventually results in a global fragmentation of the bow shock front. The formation of a thermal instability is supported by analysis of the plasma cooling function calculated for the experimental conditions with the radiative packages ABAKO/RAPCAL.

  4. Bow shock nebulae of hot massive stars in a magnetized medium

    NASA Astrophysics Data System (ADS)

    Meyer, D. M.-A.; Mignone, A.; Kuiper, R.; Raga, A.; Kley, W.

    2016-10-01

    A significant fraction of OB-type, main-sequence massive stars are classified as runaway and move supersonically through the interstellar medium (ISM). Their strong stellar winds interact with their surroundings where the typical strength of the local ISM magnetic field is about 3.5-7 μ G, which can result in the formation of bow shock nebulae. We investigate the effects of such magnetic fields, aligned with the motion of the flow, on the formation and emission properties of these circumstellar structures. Our axisymmetric, magneto-hydrodynamical simulations with optically-thin radiative cooling, heating and anisotropic thermal conduction show that the presence of the background ISM magnetic field affects the projected optical emission our bow shocks at Hα and [OIII] λ 5007 which become fainter by about 1-2 orders of magnitude, respectively. Radiative transfer calculations against dust opacity indicate that the magnetic field slightly diminishes their projected infrared emission and that our bow shocks emit brightly at 60 μ m. This may explain why the bow shocks generated by ionizing runaway massive stars are often difficult to identify. Finally, we discuss our results in the context of the bow shock of ζ Ophiuchi and we support the interpretation of its imperfect morphology as an evidence of the presence of an ISM magnetic field not aligned with the motion of its driving star.

  5. The dynamics of Bow-shock Pulsar Wind Nebula: Reconstruction of multi-bubbles

    NASA Astrophysics Data System (ADS)

    Yoon, Doosoo; Heinz, Sebastian

    2014-08-01

    Bow-shock pulsar wind nebulae (PWNe) exhibit a characteristic cometary shape due to the supersonic motion of the pulsar interacting with the interstellar medium (ISM). One of the spectacular bow-shock is the Guitar Nebula, which is produced by the fast pulsar PSR B2224+65 (vpsr > 1000 km s-1 ), and consists of a bright head, a faint neck, a two larger bubbles. We present that the peculiar mophology arises from variations in the interstellar medium density. We perform 3-D hydrodynamic simulation to understand the evolution of the pulsar as its moves through the density discontinuity. We found that when the pulsar encounters the low-density medium, the pressure balance at the head of the bow shock begins to collapse, producing the second bubble. The expansion rate of the bubble is related to the properties of both the pulsar and the ambient medium. Assuming that the pulsar’s properties, including spin-down energy, are constant, we conclude that the ambient density around the second bubble should be 4.46 times larger than around the first bubble in the Guitar body. We further found that when the pulsar encounters the inclined density dicontinuity, it can produce the asymmetric shape of the bow shock observed in a subset of bow-shock PWNe including J2124-3358.

  6. Kinematic features of a bow echo in southern China observed with doppler radar

    NASA Astrophysics Data System (ADS)

    Peng, Xindong; Zhang, Renhe; Wang, Hongyan

    2013-11-01

    A bow echo is a type of mesoscale convective phenomenon that often induces extreme weather and appears with strong reflectivity on radar images. A strong bow echo that developed from a supercell was observed over Foshan City in southern China on 17 April 2011. The intense gusty winds and showers caused huge losses of property and severely affected human lives. This paper presents an analysis of this strong meso- β-scale convective system based on Doppler radar observations. The isolated bow echo exhibited a horizontal scale of about 80 km in terms of reflectivity above 40 dB Z, and a life span of 8 hours. The system originated from the merging of a couple of weakly organized cells in a shear line, and developed into an arch shape as it moved through the shear zone. Sufficient surface moisture supply ensured the convective instability and development of the bow echo. The low-altitude winds retrieved from single Doppler radar observations showed an obvious rear-inflow jet along the notch area. Different from the conventional definition, no bookend anticyclone was observed throughout the life cycle. Very strong slantwise updrafts and downdrafts were recognizable from the retrieved winds, even though the spatial scale of the bow echo was small. Strong winds and induced damage on the surface are considered to have been caused by the mid-level rear-inflow jet and intense convective downdrafts.

  7. Bow-tie antennas on a dielectric half-space - Theory and experiment

    NASA Technical Reports Server (NTRS)

    Compton, Richard C.; Mcphedran, Ross C.; Popovic, Zorana; Rebeiz, Gabriel M.; Tong, Peter P.

    1987-01-01

    A new formulation is discussed for the rigous calculation of the radiation pattern of a bow-tie antenna of finite length and infinitesimal thickness, placed on a lossless dielectric substrate. The analysis is based on a representation of the current density on the metal surface of the antenna as a sum of an imposed (quasistatic) term and a set of current modes with unknown amplitudes. Free-space fields that are expressed in terms of continuous spectra of symmetrized plane waves are matched to the current modes using the method of moments. The resulting set of equations are solved for the unknown current amplitudes. The calculations show that for increasing bow length the antenna impedance spirals rapidly to a value predicted by transmission line theory. The theory also shows that the E-plane pattern of a two-wavelength, 60-deg bow-tie antenna is dominated by low-loss current modes propagating at the dielectric wavenumber. As the bow tie narrows, the loss of the modes increases, and the dominant wavenumber tends to the quasi-static value. Pattern measurements made at 94 GHz are shown to agree well with theoretical predictions. Measurements for a long-wire antenna, a linear array of bow-tie elements, and a log-periodic antenna are also presented.

  8. Face-bow transfer in prosthodontics: a systematic review of the literature.

    PubMed

    Farias-Neto, A; Dias, A H M; de Miranda, B F S; de Oliveira, A R

    2013-09-01

    An extensive search for randomised controlled clinical trials was accomplished to compare dental prostheses and occlusal splints constructed with or without face-bow transfer, and question whether face-bow transfer may present better clinical results than simpler approaches. Studies were identified by searching electronic databases (PubMed/MEDLINE, Latin American and Caribbean Literature on the Health Science, and Brazilian Bibliography of Dentistry). The keywords 'dental articulator', 'semi-adjustable articulator', 'face-bow', 'jaw relation record' and 'occlusal splint therapy' were used. The minimum inclusion requirements were (i) randomised controlled trials with patients of any age, (ii) comparison between dental prostheses or occlusal splints constructed with or without face-bow transfer and (iii) assessment of clinician's time, number of occlusal contacts, patient satisfaction or masticatory function. The search resulted in the identification of 8779 articles. Subsequently, 8763 articles were excluded on the basis of title and abstract. By the end of the search phase, eight randomised controlled trials were considered eligible. Current scientific evidence suggests that face-bow transfer is not imperative to achieve better clinical results in prosthodontics. Randomised clinical trials suggest that simpler approaches for the construction of complete dentures and occlusal splints may present acceptable results, while no clinical study has investigated its use in fixed and removable partial dentures.

  9. An experimental evaluation of effects and side effects of asymmetric face-bows in the light of in vivo measurements of initial tooth movements.

    PubMed

    Yoshida, N; Jost-Brinkmann, P G; Miethke, R R; König, M; Yamada, Y

    1998-05-01

    By using a magnetic sensing system, the translational and rotational molar movements under the application of various asymmetric face-bows were measured two-dimensionally in human subjects to evaluate their primary effects and side effects. The asymmetric face-bow designs tested were three types of power arm face-bows, swivel offset face-bow, and internal hinge face-bow. Although all face-bow designs were considered to be effective in achieving asymmetric distalizations of the molars, they generated lateral displacements that may lead to an undesirable crossbite. The swivel offset face-bow may produce unexpected results and its fabrication is complicated. The internal hinge face-bow is remarkably effective for asymmetric molar distalizations. Unfortunately, it causes a strong crossbite tendency on the molar to be more distalized. Therefore the use of the power arm face-bow is thought to be relatively recommendable because it showed an acceptable asymmetric effect and is easily fabricated from a commercially available face-bow. It is concluded that all asymmetric face-bows generate lateral forces as side effects as long as the force delivery system with a combination of an asymmetric face-bow and a neck strap or head cap is applied. The current study suggests a method whereby the side effect of asymmetric face-bows can be eliminated.

  10. Studies with Cluster upstream and downstream of the bow shock: An experimenter's perspective

    NASA Technical Reports Server (NTRS)

    Moebius, E.

    1995-01-01

    Some open questions in the physics of bow shock formation, the evolution of the particle distributions from solar wind into the magnetosheath, and the acceleration of ions at the moment of the shock are summarized. A layout of the current situation is presented in view of recent theoretical developments and the new diagnostic tools provided by the Cluster mission. The transition of ions across the quasi-perpendicular bow shock and their downstream thermalization are discussed. The processes and spatial scales are found to be species dependent and are discussed for H(+), He(2+), and He(+). The theory of particle acceleration at quasi-parallel shocks are reviewed. It is shown how Cluster can study the time variable structures of the shock as predicted by hybrid simulation. It is emphasized that high time resolution measurement with simultaneous species separation is necessary for the study of the ion acceleration. Suggestions for the spacecraft separations at the bow shock are suggested.

  11. Transport of Solar Wind H+ and He++ Ions across Earth’s Bow Shock

    NASA Astrophysics Data System (ADS)

    Parks, G. K.; Lee, E.; Fu, S. Y.; Kim, H. E.; Ma, Y. Q.; Yang, Z. W.; Liu, Y.; Lin, N.; Hong, J.; Canu, P.; Dandouras, I.; Rème, H.; Goldstein, M. L.

    2016-07-01

    We have investigated the dependence of mass, energy, and charge of solar wind (SW) transport across Earth’s bow shock. An examination of 111 crossings during quiet SW in both quasi-perpendicular and quasi-parallel shock regions shows that 64 crossings had various degrees of heating and thermalization of SW. We found 22 crossings where the SW speed was <400 km s‑1. The shock potential of a typical supercritical quasi-perpendicular shock estimated from deceleration of the SW and cutoff energy of electron flat top distribution is ˜50 Volts. We find that the temperatures of H+ and He++ beams that penetrate the shock can sometimes be nearly the same in the upstream and downstream regions, indicating little or no heating had occurred crossing the bow shock. None of the models predict that the SW can cross the bow shock without heating. Our observations are important constraints for new models of collisionless shocks.

  12. Near-field radiation of bow-tie antennas and apertures at optical frequencies.

    PubMed

    Sendur, K; Challener, W

    2003-06-01

    We investigate the ability of the bow-tie slot antenna to generate intense optical spots below the diffraction limit. A commercially available finite-difference time-domain electromagnetic modelling software is used in the numerical simulations. The finite-difference time-domain software is first compared to analytical results at optical frequencies to verify its accuracy. We then present numerical simulations for various geometries involving apertures on thin films and the bow-tie antenna. The transmission efficiency and optical spot size of the bow-tie antenna are compared with those of rectangular and circular apertures on thin metal films. We also investigate the effects of material composition, frequency, and antenna geometry on the near-field radiation pattern using numerical simulations. PMID:12787099

  13. A numerical study on bow shocks around the lightning return stroke channel

    SciTech Connect

    Chen, Qiang Chen, Bin Yi, Yun; Chen, P. F.; Mao, Yunfei; Xiong, Run

    2015-03-15

    Bow shock structures are important to various hydrodynamics and magnetohydrodynamics (MHD) phenomena in geophysics and astrophysics. The formation and propagation of bow shocks around the lightning return stroke channel are investigated based on the self-similar motion theory and simulated with a two-dimensional Eulerian finite volume resistive radiation MHD code. In this framework, as verification of theoretical models, the evolving structures of many quantities, such as the plasma density, temperature, pressure, shock velocity, and magnetic field, can be obtained, which present all the characteristics of bow shocks in the lightning return stroke processes. The evolution characteristics and the configuration of the curved return stroke channels, e.g., the non-ideal effects and the scaling laws, are discussed in detail. The results may have applications for some observed features of the return stroke channels and other phenomena in the lightning discharge plasmas.

  14. Transport of Solar Wind H+ and He++ Ions across Earth’s Bow Shock

    NASA Astrophysics Data System (ADS)

    Parks, G. K.; Lee, E.; Fu, S. Y.; Kim, H. E.; Ma, Y. Q.; Yang, Z. W.; Liu, Y.; Lin, N.; Hong, J.; Canu, P.; Dandouras, I.; Rème, H.; Goldstein, M. L.

    2016-07-01

    We have investigated the dependence of mass, energy, and charge of solar wind (SW) transport across Earth’s bow shock. An examination of 111 crossings during quiet SW in both quasi-perpendicular and quasi-parallel shock regions shows that 64 crossings had various degrees of heating and thermalization of SW. We found 22 crossings where the SW speed was <400 km s-1. The shock potential of a typical supercritical quasi-perpendicular shock estimated from deceleration of the SW and cutoff energy of electron flat top distribution is ˜50 Volts. We find that the temperatures of H+ and He++ beams that penetrate the shock can sometimes be nearly the same in the upstream and downstream regions, indicating little or no heating had occurred crossing the bow shock. None of the models predict that the SW can cross the bow shock without heating. Our observations are important constraints for new models of collisionless shocks.

  15. Induced anticlinic ordering and nanophase segregation of bow-shaped molecules in a smectic solvent.

    PubMed

    Maiti, Prabal K; Lansac, Yves; Glaser, Matthew A; Clark, Noel A

    2002-02-11

    Recent experiments indicate that doping low concentrations of bent-core molecules into calamitic smectic solvents can induce anticlinic and biaxial smectic phases. We have carried out Monte Carlo simulations of mixtures of rodlike molecules (hard spherocylinders with length/breadth ratio L(rod)/D = 5) and bow-shaped molecules (hard spherocylinder dimers with length/breadth ratio L(ban)/D = 5 or 2.5 and opening angle psi). We find that a low concentration ( 3%) of L(ban)/D = 5 dimers induces anticlinic ( SmC(A)) ordering in an untilted smectic ( SmA) phase for 100 < or = psi < 150. For L(ban)/D = 2.5, no tilted phases are induced. However, with decreasing psi we observe a sharp transition from intralamellar nanophase segregation (bow-shaped molecules segregated within smectic layers) to interlamellar nanophase segregation (bow-shaped molecules concentrated between smectic layers) near psi = 130.

  16. Numerical Simulation of the SVS 13 Microjet and Bow Shock Bubble

    NASA Astrophysics Data System (ADS)

    Gardner, Carl L.; Jones, Jeremiah R.; Hodapp, Klaus W.

    2016-10-01

    Numerical simulations of the SVS 13 microjet and bow shock bubble are performed using the WENO method that reproduces the main features and dynamics of data from the Keck Telescope/OSIRIS velocity-resolved integral field spectrograph: an expanding, cooler bow shock bubble, with the bubble center moving at approximately 50 km s‑1 with a radial expansion velocity of 11 km s‑1, surrounding the fast, hotter jet, which is propagating at 156 km s‑1. Contact and bow shock waves are visible in the simulations both from the initial short jet pulse that creates the nearly spherical bow shock bubble and from the fast microjet, while a terminal Mach disk shock is visible near the tip of the continuous microjet, which reduces the velocity of the jet gas down to the flow velocity of the contact discontinuity at the leading edge of the jet. At 21.1 years after the launch of the initial bubble pulse, the jet has caught up with and penetrated almost all the way across the bow shock bubble of the slower initial pulse. At times later than about 22 years, the jet has penetrated through the bubble and thereafter begins to subsume its spherical form. Emission maps from the simulations of the jet—traced by the emission of the shock-excited 1.644 μm [Fe ii] line—and the bow shock bubble—traced in the lower excitation 2.122 μm H2 1–0 S(1) line—projected onto the plane of the sky are presented, and are in good agreement with the Keck observations.

  17. 76 FR 9320 - Foreign-Trade Zone 274-Butte-Silver Bow, MT; Application for Manufacturing Authority REC Silicon...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 274--Butte-Silver Bow, MT; Application for Manufacturing... Foreign-Trade Zones Board (the Board) by the City and County of Butte-Silver Bow, grantee of FTZ...

  18. 77 FR 16028 - Broken Bow Wind, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Broken Bow Wind, LLC; Supplemental Notice That Initial Market- Based Rate...-referenced proceeding of Broken Bow Wind, LLC's application for market-based rate authority, with...

  19. Voyager energetic particle observations at interplanetary shocks and upstream of planetary bow shocks - 1977-1990

    NASA Technical Reports Server (NTRS)

    Krimigis, S. M.

    1992-01-01

    The Voyager 1 and 2 vehicles include instrumentation that makes comprehensive electron and ion measurements in several energy channels with good energy, temporal, and compositional resolution. Data gathered from 1977 to 1988, including observations downstream and upstream of four planetary bow shocks (earth, Saturn, Uranus, Jupiter) and numerous interplanetary shocks to about 30 AU, are analyzed in the context of the Fermi and shock drift acceleration models. Overall results indicate that electrons and ions observed upstream of planetary bow shocks have their source inside the parent magnetosphere, with first order Fermi acceleration playing a secondary role at best.

  20. Asymptotic Steady-state Solution to a Bow Shock with an Infinite Mach Number

    NASA Astrophysics Data System (ADS)

    Yalinewich, Almog; Sari, Re'em

    2016-08-01

    The problem of a cold gas flowing past a stationary obstacle is considered. We study the bow shock that forms around the obstacle and show that at large distances from the obstacle the shock front forms a parabolic solid of revolution. The profiles of the hydrodynamic variables in the interior of the shock are obtained by solution of the hydrodynamic equations in parabolic coordinates. The results are verified with a hydrodynamic simulation. The drag force on the obstacle is also calculated. Finally, we use these results to model the bow shock around an isolated neutron star.

  1. THEMIS Observations of Unusual Bow Shock Motion, Attending a Transient Magnetospheric Event

    NASA Technical Reports Server (NTRS)

    Korotova, Galina; Sibeck, David; Omidi, N.; Angelopoulos, V.

    2013-01-01

    We present a multipoint case study of solar wind and magnetospheric observations during a transient magnetospheric compression at 2319 UT on October 15, 2008. We use high-time resolution magnetic field and plasma data from the THEMIS and GOES-11/12 spacecraft to show that this transient event corresponded to an abrupt rotation in the IMF orientation, a change in the location of the foreshock, and transient outward bow shock motion. We employ results from a global hybrid code model to reconcile the observations indicating transient inward magnetopause motion with the outward bow shock motion.

  2. One-way calcium spill-over during signal transduction in Paramecium cells: from the cell cortex into cilia, but not in the reverse direction.

    PubMed

    Husser, Marc R; Hardt, Martin; Blanchard, Marie-Pierre; Hentschel, Joachim; Klauke, Norbert; Plattner, Helmut

    2004-11-01

    We asked to what extent Ca(2+) signals in two different domains of Paramecium cells remain separated during different stimulations. Wild-type (7S) and pawn cells (strain d4-500r, without ciliary voltage-dependent Ca(2+)-channels) were stimulated for trichocyst exocytosis within 80 ms by quenched-flow preparation and analysed by energy-dispersive X-ray microanalysis (EDX), paralleled by fast confocal fluorochrome analysis. We also analysed depolarisation-dependent calcium signalling during ciliary beat rerversal, also by EDX, after 80-ms stimulation in the quenched-flow mode. EDX and fluorochrome analysis enable to register total and free intracellular calcium concentrations, [Ca] and [Ca(2+)], respectively. After exocytosis stimulation we find by both methods that the calcium signal sweeps into the basis of cilia, not only in 7S but also in pawn cells which then also perform ciliary reversal. After depolarisation we see an increase of [Ca] along cilia selectively in 7S, but not in pawn cells. Opposite to exocytosis stimulation, during depolarisation no calcium spill-over into the nearby cytosol and no exocytosis occurs. In sum, we conclude that cilia must contain a very potent Ca(2+) buffering system and that ciliary reversal induction, much more than exocytosis stimulation, involves strict microdomain regulation of Ca(2+) signals.

  3. Fine-tuning of catalytic tin nanoparticles by the reverse micelle method for direct deposition of silicon nanowires by a plasma-enhanced chemical vapour technique.

    PubMed

    Poinern, Gérrard E J; Ng, Yan-Jing; Fawcett, Derek

    2010-12-15

    The reverse micelle method was used for the reduction of a tin (Sn) salt solution to produce metallic Sn nanoparticles ranging from 85 nm to 140 nm in diameter. The reverse micellar system used in this process was hexane-butanol-cetyl trimethylammonium bromide (CTAB). The diameters of the Sn nanoparticles were proportional to the concentration of the aqueous Sn salt solution. Thus, the size of the Sn nanoparticles can easily be controlled, enabling a simple, reproducible mechanism for the growth of silicon nanowires (SiNWs) using plasma-enhanced chemical vapour deposition (PECVD). Both the Sn nanoparticles and silicon nanowires were characterised using field-emission scanning electron microscopy (FE-SEM). Further characterisations of the SiNW's were made using transmission electron microscopy (TEM), atomic force microscopy (AFM) and Raman spectroscopy. In addition, dynamic light scattering (DLS) was used to investigate particle size distributions. This procedure demonstrates an economical route for manufacturing reproducible silicon nanowires using fine-tuned Sn nanoparticles for possible solar cell applications.

  4. A flash spectrum of Cl I, C I, N I, and Ni II absorption in 31 Cygni: A direct observation of the reversing layer

    NASA Technical Reports Server (NTRS)

    Ahmad, Imad A.

    1987-01-01

    In the process of surveying IUE observations of the zeta Aurigae binary system 31 Cygni for evidence of a shock, the presence of narrow low temperature lines Cl I, C I, N I, and Ni II has been discovered. These lines cannot be due to the local interstellar medium, since they appear only in one of the 16 high resolution, short wavelength observations made of this system. The phase of their appearance is theta = 0.017, approximately two months after egress of the blue dwarf component from eclipse behind the cool supergiant. Such lines might be produced by the shining of the hot dwarf companion's continuum through the edge of the supergiant's reversing layer or through a condensation in the supergiant atmosphere. If the former is the case, then the height of the reversing layer may be estimated from this observation. The radial velocities and equivalent widths of ten of these lines have been measured and the former is found to be -8.2 +/- 0.5 km/sec, precisely equal to the radial velocity of the system center of mass. This places a strict upper limit on the rotational velocity of the supergiant: V sub rot less than 2 km/s to better than 3 sigma.

  5. Towards an MHD Theory for the Standoff Distance of Earth's Bow Shock

    NASA Technical Reports Server (NTRS)

    Carins, Iver H.; Grabbe, Crockett L.

    1994-01-01

    A magnetohydrodynamic (MHD) theory is developed for the standoff distance a(s) of the bow shock and the thickness Delta(ms) of the magnetosheath, using the empirical Spreiter et al. relation Delta(ms) = kX and the MHD density ratio X across the shock. The theory includes as special cases the well-known gasdynamic theory and associated phenomenological MHD-like models for Delta(ms) and As. In general, however, MHD effects produce major differences from previous models, especially at low Alfev (Ma) and Sonic (Ms) Mach numbers. The magnetic field orientation Ma, Ms and the ratio of specific heats gamma are all important variables of the theory. In contrast, the fast mode Mach number need play no direct role. Three principle conclusions are reached. First the gasdynamic and phenomenological models miss important dependences of field orientation and Ms generally provide poor approximations to the MHD results. Second, changes in field orientation and Ms are predicted to cause factor of approximately 4 changes in Delta(ms) at low Ma. These effects should be important when predicting the shock's location or calculating gramma from observations. Third, using Spreiter et al.'s value for k in the MHD theory leads to maxima a(s) values at low Ma and nominal Ms that are much smaller than observations and MHD simulations require. Resolving this problem requires either the modified Spreiter-like relation and larger k found in recent MHD simulations and/or a breakdown in the Spreiter-like relation at very low Ma.

  6. Vasectomy reversal.

    PubMed

    Belker, A M

    1987-02-01

    A vasovasostomy may be performed on an outpatient basis with local anesthesia, but also may be performed on an outpatient basis with epidural or general anesthesia. Local anesthesia is preferred by most of my patients, the majority of whom choose this technique. With proper preoperative and intraoperative sedation, patients sleep lightly through most of the procedure. Because of the length of time often required for bilateral microsurgical vasoepididymostomy, epidural or general anesthesia and overnight hospitalization are usually necessary. Factors influencing the preoperative choice for vasovasostomy or vasoepididymostomy in patients undergoing vasectomy reversal are considered. The preoperative planned choice of vasovasostomy or vasoepididymostomy for patients having vasectomy reversal described herein does not have the support of all urologists who regularly perform these procedures. My present approach has evolved as the data reported in Tables 1 and 2 have become available, but it may change as new information is evaluated. However, it offers a logical method for planning choices of anesthesia and inpatient or outpatient status for patients undergoing vasectomy reversal procedures. PMID:3811050

  7. Vasectomy reversal.

    PubMed

    Belker, A M

    1987-02-01

    A vasovasostomy may be performed on an outpatient basis with local anesthesia, but also may be performed on an outpatient basis with epidural or general anesthesia. Local anesthesia is preferred by most of my patients, the majority of whom choose this technique. With proper preoperative and intraoperative sedation, patients sleep lightly through most of the procedure. Because of the length of time often required for bilateral microsurgical vasoepididymostomy, epidural or general anesthesia and overnight hospitalization are usually necessary. Factors influencing the preoperative choice for vasovasostomy or vasoepididymostomy in patients undergoing vasectomy reversal are considered. The preoperative planned choice of vasovasostomy or vasoepididymostomy for patients having vasectomy reversal described herein does not have the support of all urologists who regularly perform these procedures. My present approach has evolved as the data reported in Tables 1 and 2 have become available, but it may change as new information is evaluated. However, it offers a logical method for planning choices of anesthesia and inpatient or outpatient status for patients undergoing vasectomy reversal procedures.

  8. Directed, strong, and reversible immobilization of proteins tagged with a β-trefoil lectin domain: a simple method to immobilize biomolecules on plain agarose matrixes.

    PubMed

    López-Gallego, Fernando; Acebrón, Ivan; Mancheño, Jose Miguel; Raja, Sebastian; Lillo, M Pilar; Guisán Seijas, Jose Manuel

    2012-03-21

    A highly stable lipase from Geobacillus thermocatenolatus (BTL2) and the enhanced green fluorescent protein from Aquorea victoria (EGFP) were recombinantly produced N-terminally tagged to the lectin domain of the hemolytic pore-forming toxin LSLa from the mushroom Laetiporus sulphureus . Such a domain (LSL(150)), recently described as a novel fusion tag, is based on a β-trefoil scaffold with two operative binding sites for galactose or galactose-containing derivatives. The fusion proteins herein analyzed have enabled us to characterize the binding mode of LSL(150) to polymeric and solid substrates such as agarose beads. The lectin-fusion proteins are able to be quantitatively bound to both cross-linked and non-cross-linked agarose matrixes in a very rapid manner, resulting in a surprisingly dynamic protein distribution inside the porous beads that evolves from heterogeneous to homogeneous along the postimmobilization time. Such dynamic distribution can be related to the reversible nature of the LSL(150)-agarose interaction. Furthermore, this latter interaction is temperature dependent since it is 4-fold stronger when the immobilization takes place at 25 °C than when it does at 4 °C. The strongest lectin-agarose interaction is also quite stable under a survey of different conditions such as high temperatures (up to 60 °C) or high organic solvent concentrations (up to 60% of acetonitrile). Notably, the use of cross-linked agarose would endow the system with more robustness due to its better mechanical properties compared to the noncross-linked one. The stability of the LSL(150)-agarose interaction would prevent protein leaching during the operation process unless high pH media are used. In summary, we believe that the LSL(150) lectin domain exhibits interesting structural features as an immobilization domain that makes it suitable to reversibly immobilize industrially relevant enzymes in very simple carriers as agarose.

  9. Defining the Polar Field Reversal

    NASA Technical Reports Server (NTRS)

    Upton, Lisa; Hathaway, David H.

    2013-01-01

    The polar fields on the Sun are directly related to solar cycle variability. Recently there has been interest in studying an important characteristic of the polar fields: the timing of the polar field reversals. However this characteristic has been poorly defined, mostly due to the limitations of early observations. In the past, the reversals have been calculated by averaging the flux above some latitude (i.e. 55deg or 75deg). Alternatively, the reversal could be defined by the time in which the previous polarity is completely canceled and replaced by the new polarity at 90de, precisely at the pole. We will use a surface flux transport model to illustrate the differences in the timing of the polar field reversal based on each of these definitions and propose standardization in the definition of the polar field reversal. The ability to predict the timing of the polar field reversal using a surface flux transport model will also be discussed.

  10. Reverse shift mechanism for automotive manual transmission

    SciTech Connect

    Inui, M.; Ogawa, S.

    1987-03-03

    A reverse shift mechanism is described for an automotive manual transmission of a type having a reverse idler gear which is movable to selectively complete a reverse gear train, the reverse shift mechanism comprising: a reverse shift arm having a portion disposed adjacent the reverse idler gear and pivotally carried with respect to a transmission casing so that the portion rocks along a direction of axis of the reverse idler gear in response to shifting operation. The portion of the reverse shift arm is provided with a blind hole which is open at a first end toward the reverse idler gear and is closed at a second end away from the reverse idler gear; and a shift arm shoe carried by the portion of the reverse shift arm adjacent the reverse idler gear for pushing the reverse idler gear. The shift arm shoe has an end adapted to engage with a circumferential groove formed in the reverse idler gear and an opposing end shaped to fit in the blind hole of the reverse shift arm; whereby the shift arm shoe is prevented from coming off during assembly by virtue of a vacuum effect created by air confined in the blind hole by fitting engagement between the opposing end and the blind hole, and is held in place after assembly by being clamped between the groove of the reverse idler gear and the blind hole of the reverse shift arm.

  11. Venusian ion populations and bow shock as seen by the ASPERA-4 ion instrument on Venus Express

    NASA Astrophysics Data System (ADS)

    Grande, M.; Whittaker, I.; Guymer, G.; Barabash, S.

    2008-09-01

    Introduction We examine ion populations at Venus. Previous models use magnetic crossing points to derive the bow shock position. The current work uses data from the ASPERA-4 (Analyser of Space Plasmas and Energetic Atoms) [1] instrument to measure ion populations and derive a bow shock position at Venus. Instrumentation The ASPERA-4 instrument flies onboard Venus Express (VEX) and is comprised of five different detectors (Barabash et al 2006 [1]). A neutral particle detector and analyser, an electron spectrometer and the Ion Mass Analyser (IMA) (ref). This paper uses the IMA instrument for all its data and an explanation of the specifications is required. The instrument is a top hat electrostatic analyser; it runs through voltages to scan look angles and also acceptance energies. In one look direction it scans through 96 different energy values before changing to the next. A full scan of all look directions and energies takes 192 seconds. Data Collection All data is weighed dependant upon its probability of the spacecraft measuring at a particular point and when fitted produces a value of 1.24 RV, somewhat closer distance for the sub solar point than previous authors - see figure 1. We separate the data according to slow or fast solar wind and not the similarities and differences in the results derived. The inbound and outbound bow shock crossings were taken by inspection of 106 orbits between November 2006 and February 2007. Any orbits where the crossing point was not clear or with data missing were ignored. The occupational probability is found from orbital mechanics. By setting up a grid and deriving the amount of time it takes to cross each square the probability as a whole can then be determined. Ion distribution plots Two dimensional maps of the ions are produced and the bow shock model overplotted to verify its accuracy, as shown in figure 3. The test of the bow shock is to place it upon real data and examine the fit. To do this ion distribution plots are

  12. Prototype adaptive bow-tie filter based on spatial exposure time modulation

    NASA Astrophysics Data System (ADS)

    Badal, Andreu

    2016-03-01

    In recent years, there has been an increased interest in the development of dynamic bow-tie filters that are able to provide patient-specific x-ray beam shaping. We introduce the first physical prototype of a new adaptive bow-tie filter design based on the concept of "spatial exposure time modulation." While most existing bow-tie filters operate by attenuating the radiation beam differently in different locations using partially attenuating objects, the presented filter shapes the radiation field using two movable completely radio-opaque collimators. The aperture and speed of the collimators is modulated in synchrony with the x-ray exposure to selectively block the radiation emitted to different parts of the object. This mode of operation does not allow the reproduction of every possible attenuation profile, but it can reproduce the profile of any object with an attenuation profile monotonically decreasing from the center to the periphery, such as an object with an elliptical cross section. Therefore, the new adaptive filter provides the same advantages as the currently existing static bow-tie filters, which are typically designed to work for a pre-determined cylindrical object at a fixed distance from the source, and provides the additional capability to adapt its performance at image acquisition time to better compensate for the actual diameter and location of the imaged object. A detailed description of the prototype filter, the implemented control methods, and a preliminary experimental validation of its performance are presented.

  13. Sociopolitical effects of bow and arrow technology in prehistoric coastal California.

    PubMed

    Kennett, Douglas J; Lambert, Patricia M; Johnson, John R; Culleton, Brendan J

    2013-01-01

    Bow and arrow technology spread across California between ∼AD 250 and 1200, first appearing in the intermountain deserts of the Great Basin and later spreading to the coast. We critically evaluate the available data for the initial spread in bow and arrow technology and examine its societal effects on the well-studied Northern Channel Islands off the coast of Southern California. The introduction of this technology to these islands between AD 650 and 900 appears to predate the appearance of hereditary inequality between AD 900 and 1300. We conclude, based on the available data, that this technology did not immediately trigger intergroup warfare. We argue that the introduction of the bow and arrow contributed to sociopolitical instabilities that were on the rise within the context of increasing population levels and unstable climatic conditions, which stimulated intergroup conflict and favored the development of hereditary inequality. Population aggregation and economic intensification did occur with the introduction of the bow and arrow. This observation is consistent with the hypothesis that social coercion via intra-group "law enforcement" contributed to changes in societal scale that ultimately resulted in larger groups that were favored in inter-group conflict. We argue that the interplay between intra-group "law enforcement" and inter-group warfare were both essential for the ultimate emergence of social inequality between AD 900 and 1300.

  14. Further evidence for a dynamically generated secondary bow in 13C+12C rainbow scattering

    NASA Astrophysics Data System (ADS)

    Ohkubo, S.; Hirabayashi, Y.; Ogloblin, A. A.

    2015-11-01

    The existence of a secondary bow is confirmed for 13C+12C nuclear rainbow scattering in addition to the 16O+12C system. This is found by studying the experimental angular distribution of 13C+12C scattering at the incident 13C energy EL=250 MeV with an extended double-folding (EDF) model that describes all the diagonal and off-diagonal coupling potentials derived from the microscopic wave functions for 12C using a density-dependent nucleon-nucleon force. The Airy minimum at θ ≈70°, which is not reproduced by a conventional folding potential, is revealed to be a secondary bow generated dynamically by a coupling to the excited state 2+ (4.44 MeV) of 12C. The essential importance of the quadruple Y 2 term (reorientation term) of potential of the excited state 2+ of 12C for the emergence of a secondary bow is found. The mechanism of the secondary bow is intuitively explained by showing how the trajectories are refracted dynamically into the classically forbidden angular region beyond the rainbow angle of the primary rainbow.

  15. Fuzzy Bayesian Network-Bow-Tie Analysis of Gas Leakage during Biomass Gasification

    PubMed Central

    Yan, Fang; Xu, Kaili; Yao, Xiwen; Li, Yang

    2016-01-01

    Biomass gasification technology has been rapidly developed recently. But fire and poisoning accidents caused by gas leakage restrict the development and promotion of biomass gasification. Therefore, probabilistic safety assessment (PSA) is necessary for biomass gasification system. Subsequently, Bayesian network-bow-tie (BN-bow-tie) analysis was proposed by mapping bow-tie analysis into Bayesian network (BN). Causes of gas leakage and the accidents triggered by gas leakage can be obtained by bow-tie analysis, and BN was used to confirm the critical nodes of accidents by introducing corresponding three importance measures. Meanwhile, certain occurrence probability of failure was needed in PSA. In view of the insufficient failure data of biomass gasification, the occurrence probability of failure which cannot be obtained from standard reliability data sources was confirmed by fuzzy methods based on expert judgment. An improved approach considered expert weighting to aggregate fuzzy numbers included triangular and trapezoidal numbers was proposed, and the occurrence probability of failure was obtained. Finally, safety measures were indicated based on the obtained critical nodes. The theoretical occurrence probabilities in one year of gas leakage and the accidents caused by it were reduced to 1/10.3 of the original values by these safety measures. PMID:27463975

  16. Wake Characteristics of the MOD-2 Wind Turbine at Medicine Bow, Wyoming

    SciTech Connect

    Jacobs, E. W.; Kelley, N. D.; McKenna, H. E.; Birkenheuer, N. B.

    1984-11-01

    The present paper summarizes results obtained from profile measurements of the MOD-2 wind turbine wake at Medicine Bow, Wyoming. Vertical profiles of wind speed, potential temperature, and turbulence at 3 and 7 rotor diameters downstream of the turbine, taken under near neutral or slightly stable atmospheric conditions, are presented.

  17. 76 FR 65717 - City of Broken Bow, OK; Notice of Availability of Final Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... Commission's (Commission or FERC) regulations, 18 CFR part 380 (Order No. 486, 52 FR 47897), the Office of... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission City of Broken Bow, OK; Notice of Availability of Final...

  18. 75 FR 33290 - City of Broken Bow, OK; Notice of Availability of Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... Regulatory Commission's (Commission) regulations, 18 CFR part 380 (Order No. 486, 52 FR 47897), the Office of... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission City of Broken Bow, OK; Notice of Availability of Environmental...

  19. Investigation of plasma density bulge in front of Venus bow shock. Final technical report

    SciTech Connect

    Not Available

    1990-01-01

    Significant ion and electron flux enhancements immediately upstream of the Venus bow shock were observed by the Electron Temperature Probe on the Pioneer Venus Orbiter. Mass loading of the solar wind by oxygen ions accounts for only about 10 percent of the observed effect.

  20. Plane parallel and bow-shock models of Herbig-Haro Objects

    SciTech Connect

    Raga, A.C.

    1986-01-01

    A model for a bow shock formed around a bullet (which moves supersonically with respect to the surrounding medium) is developed, and is then used to predict position velocity diagrams (i.e., long-slit spectra) and two-dimensional intensity contour maps for several emission lines. In practice, the thesis is divided into two parts: (1) a calculation of stationary, plane-parallel shock-wave models, in which a full treatment of a pre-shock region is included. The emission line spectra of both the pre- and the post-shock regions are predicted. (2) The development of a bow shock model (for a gas with an important radiative energy loss), from which the spatially resolved line spectrum is predicted. A qualitative comparison of the predictions from the blow shock models with recent observations of Herbig-Haro objects HH 1 and HH 32 shows that, at least for these two objects, a good agreement between the observations and the theory of a radiating bow shock is obtained. This seems to indicate that the emission line spectra of these two Herbig-Haro objects are formed (at least to a large extent) in the recombination region behind a bow shock.

  1. Turbulence at quasi-parallel and quasi-perpendicular bow shocks

    NASA Astrophysics Data System (ADS)

    Pitna, Alexander; Zastenker, Georgy; Nemecek, Zdenek; Safrankova, Jana

    2016-07-01

    A solar wind is a highly turbulent medium carrying various modes of magnetohydrodynamic and kinetic instabilities. During its supersonic expansion, it meets obstacles like planetary magnetospheres and bow shocks are formed. Depending on the orientation of the ambient magnetic field with respect to the local shock normal, either quasi-parallel or quasi-perpendicular shocks can be formed. Particles reflected at the ramp of the quasi-parallel shock are streaming far upstream along the magnetic field lines, giving rise to all sorts of instabilities like SLAMS and ULF waves. In the case of the quasi-perpendicular bow shock, the reflected particles influence only a narrow upstream region of the order of the proton gyroradius but the downstream plasma becomes highly turbulent regardless of the shock type. We analyze the high cadence (31 ms) data from the BMSW instrument onboard the Spektr-R spacecraft and compare the frequency spectra of observed turbulence in MHD and kinetic ranges in upstream and downstream regions of the supercritical quasi-parallel and quasi-perpendicular bow shocks. We found that the change in the fluctuation level (from upstream to downstream) as well as the spectral indices differ substantially in the MHD and kinetic ranges for both types of bow shock.

  2. 10. VIEW TOWARD PORT BOW IN THE FOC'S'LE OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. VIEW TOWARD PORT BOW IN THE FOC'S'LE OF THE EVELINA M. GOULART. OBJECT IN THE FOREGROUND IS A FOLDING MESS TABLE LOCATED BETWEEN THE TIERS OF BUNKS. - Auxiliary Fishing Schooner "Evelina M. Goulart", Essex Shipbuilding Museum, 66 Main Street, Essex, Essex County, MA

  3. Fuzzy Bayesian Network-Bow-Tie Analysis of Gas Leakage during Biomass Gasification.

    PubMed

    Yan, Fang; Xu, Kaili; Yao, Xiwen; Li, Yang

    2016-01-01

    Biomass gasification technology has been rapidly developed recently. But fire and poisoning accidents caused by gas leakage restrict the development and promotion of biomass gasification. Therefore, probabilistic safety assessment (PSA) is necessary for biomass gasification system. Subsequently, Bayesian network-bow-tie (BN-bow-tie) analysis was proposed by mapping bow-tie analysis into Bayesian network (BN). Causes of gas leakage and the accidents triggered by gas leakage can be obtained by bow-tie analysis, and BN was used to confirm the critical nodes of accidents by introducing corresponding three importance measures. Meanwhile, certain occurrence probability of failure was needed in PSA. In view of the insufficient failure data of biomass gasification, the occurrence probability of failure which cannot be obtained from standard reliability data sources was confirmed by fuzzy methods based on expert judgment. An improved approach considered expert weighting to aggregate fuzzy numbers included triangular and trapezoidal numbers was proposed, and the occurrence probability of failure was obtained. Finally, safety measures were indicated based on the obtained critical nodes. The theoretical occurrence probabilities in one year of gas leakage and the accidents caused by it were reduced to 1/10.3 of the original values by these safety measures.

  4. Fuzzy Bayesian Network-Bow-Tie Analysis of Gas Leakage during Biomass Gasification.

    PubMed

    Yan, Fang; Xu, Kaili; Yao, Xiwen; Li, Yang

    2016-01-01

    Biomass gasification technology has been rapidly developed recently. But fire and poisoning accidents caused by gas leakage restrict the development and promotion of biomass gasification. Therefore, probabilistic safety assessment (PSA) is necessary for biomass gasification system. Subsequently, Bayesian network-bow-tie (BN-bow-tie) analysis was proposed by mapping bow-tie analysis into Bayesian network (BN). Causes of gas leakage and the accidents triggered by gas leakage can be obtained by bow-tie analysis, and BN was used to confirm the critical nodes of accidents by introducing corresponding three importance measures. Meanwhile, certain occurrence probability of failure was needed in PSA. In view of the insufficient failure data of biomass gasification, the occurrence probability of failure which cannot be obtained from standard reliability data sources was confirmed by fuzzy methods based on expert judgment. An improved approach considered expert weighting to aggregate fuzzy numbers included triangular and trapezoidal numbers was proposed, and the occurrence probability of failure was obtained. Finally, safety measures were indicated based on the obtained critical nodes. The theoretical occurrence probabilities in one year of gas leakage and the accidents caused by it were reduced to 1/10.3 of the original values by these safety measures. PMID:27463975

  5. Bowing in the Right Direction: Hiland Mountain Correctional Center Women's String Orchestra Programme

    ERIC Educational Resources Information Center

    Warfield, Duane

    2010-01-01

    The Hiland Mountain Correctional Center, a 400-bed facility for multi-level adult female offenders in Eagle River, Alaska, offers a unique educational programme to its prisoners: an orchestra. Founded in 2003, by volunteer Pati Crofut, orchestra membership grew from eight to 22 female offenders between 2003 and 2009. Crofut has devoted her time…

  6. Learning strategy refinement reverses early sensory cortical map expansion but not behavior: Support for a theory of directed cortical substrates of learning and memory.

    PubMed

    Elias, Gabriel A; Bieszczad, Kasia M; Weinberger, Norman M

    2015-12-01

    Primary sensory cortical fields develop highly specific associative representational plasticity, notably enlarged area of representation of reinforced signal stimuli within their topographic maps. However, overtraining subjects after they have solved an instrumental task can reduce or eliminate the expansion while the successful behavior remains. As the development of this plasticity depends on the learning strategy used to solve a task, we asked whether the loss of expansion is due to the strategy used during overtraining. Adult male rats were trained in a three-tone auditory discrimination task to bar-press to the CS+ for water reward and refrain from doing so during the CS- tones and silent intertrial intervals; errors were punished by a flashing light and time-out penalty. Groups acquired this task to a criterion within seven training sessions by relying on a strategy that was "bar-press from tone-onset-to-error signal" ("TOTE"). Three groups then received different levels of overtraining: Group ST, none; Group RT, one week; Group OT, three weeks. Post-training mapping of their primary auditory fields (A1) showed that Groups ST and RT had developed significantly expanded representational areas, specifically restricted to the frequency band of the CS+ tone. In contrast, the A1 of Group OT was no different from naïve controls. Analysis of learning strategy revealed this group had shifted strategy to a refinement of TOTE in which they self-terminated bar-presses before making an error ("iTOTE"). Across all animals, the greater the use of iTOTE, the smaller was the representation of the CS+ in A1. Thus, the loss of cortical expansion is attributable to a shift or refinement in strategy. This reversal of expansion was considered in light of a novel theoretical framework (CONCERTO) highlighting four basic principles of brain function that resolve anomalous findings and explaining why even a minor change in strategy would involve concomitant shifts of involved brain

  7. Reverse micelles directed synthesis of TiO{sub 2}-CeO{sub 2} mixed oxides and investigation of their crystal structure and morphology

    SciTech Connect

    Matejova, Lenka; Vales, Vaclav; Fajgar, Radek; Matej, Zdenek; Holy, Vaclav; Solcova, Olga

    2013-02-15

    The synthesis of TiO{sub 2}-CeO{sub 2} mixed oxides based on the sol-gel process controlled within reverse micelles of non-ionic surfactant Triton X-114 in cyclohexane is reported. The crystallization, phase composition, trends in nanoparticles growth and porous structure properties are studied as a function of Ti:Ce molar composition and annealing temperature by in-situ X-ray diffraction, Raman spectroscopy and physisorption. The brannerite-type CeTi{sub 2}O{sub 6} crystallizes as a single crystalline phase at Ti:Ce molar composition of 70:30 and in the mixture with cubic CeO{sub 2} and anatase TiO{sub 2} for composition 50:50. At Ti:Ce molar ratios 90:10 and 30:70 the mixtures of TiO{sub 2} anatase, rutile and cubic CeO{sub 2} appear. In these mixtures TiO{sub 2} rutile is formed at higher temperatures than conventionally. Additionally, the amount of a present amorphous phase in individual mixtures was estimated from diffraction data. The porous structure morphology depends both on molar composition and annealing temperature. This is correlated with the presence of carbon impurities of different character. - Graphical abstract: The phase composition of Ti90--Ce10 and Ti50--Ce50 oxide mixtures as a function of annealing temperature. The amount of the amorphous phase was estimated and attributed to TiO{sub 2}. Highlights: Black-Right-Pointing-Pointer Ti/Ce oxides were prepared using reverse micelles of Triton X-114. Black-Right-Pointing-Pointer Crystallization of TiO{sub 2}, CeO{sub 2} or CeTi{sub 2}O{sub 6} depends on Ti:Ce molar ratio. Black-Right-Pointing-Pointer Amorphous phase attributed to TiO{sub 2} was identified. Black-Right-Pointing-Pointer Metal oxides surface area is influenced by the character of present carbon impurities.

  8. Learning strategy refinement reverses early sensory cortical map expansion but not behavior: Support for a theory of directed cortical substrates of learning and memory.

    PubMed

    Elias, Gabriel A; Bieszczad, Kasia M; Weinberger, Norman M

    2015-12-01

    Primary sensory cortical fields develop highly specific associative representational plasticity, notably enlarged area of representation of reinforced signal stimuli within their topographic maps. However, overtraining subjects after they have solved an instrumental task can reduce or eliminate the expansion while the successful behavior remains. As the development of this plasticity depends on the learning strategy used to solve a task, we asked whether the loss of expansion is due to the strategy used during overtraining. Adult male rats were trained in a three-tone auditory discrimination task to bar-press to the CS+ for water reward and refrain from doing so during the CS- tones and silent intertrial intervals; errors were punished by a flashing light and time-out penalty. Groups acquired this task to a criterion within seven training sessions by relying on a strategy that was "bar-press from tone-onset-to-error signal" ("TOTE"). Three groups then received different levels of overtraining: Group ST, none; Group RT, one week; Group OT, three weeks. Post-training mapping of their primary auditory fields (A1) showed that Groups ST and RT had developed significantly expanded representational areas, specifically restricted to the frequency band of the CS+ tone. In contrast, the A1 of Group OT was no different from naïve controls. Analysis of learning strategy revealed this group had shifted strategy to a refinement of TOTE in which they self-terminated bar-presses before making an error ("iTOTE"). Across all animals, the greater the use of iTOTE, the smaller was the representation of the CS+ in A1. Thus, the loss of cortical expansion is attributable to a shift or refinement in strategy. This reversal of expansion was considered in light of a novel theoretical framework (CONCERTO) highlighting four basic principles of brain function that resolve anomalous findings and explaining why even a minor change in strategy would involve concomitant shifts of involved brain

  9. Reverse micelles directed synthesis of TiO2-CeO2 mixed oxides and investigation of their crystal structure and morphology

    NASA Astrophysics Data System (ADS)

    Matějová, Lenka; Valeš, Václav; Fajgar, Radek; Matěj, Zdeněk; Holý, Václav; Šolcová, Olga

    2013-02-01

    The synthesis of TiO2-CeO2 mixed oxides based on the sol-gel process controlled within reverse micelles of non-ionic surfactant Triton X-114 in cyclohexane is reported. The crystallization, phase composition, trends in nanoparticles growth and porous structure properties are studied as a function of Ti:Ce molar composition and annealing temperature by in-situ X-ray diffraction, Raman spectroscopy and physisorption. The brannerite-type CeTi2O6 crystallizes as a single crystalline phase at Ti:Ce molar composition of 70:30 and in the mixture with cubic CeO2 and anatase TiO2 for composition 50:50. At Ti:Ce molar ratios 90:10 and 30:70 the mixtures of TiO2 anatase, rutile and cubic CeO2 appear. In these mixtures TiO2 rutile is formed at higher temperatures than conventionally. Additionally, the amount of a present amorphous phase in individual mixtures was estimated from diffraction data. The porous structure morphology depends both on molar composition and annealing temperature. This is correlated with the presence of carbon impurities of different character.

  10. X-RAY EMISSION LINE PROFILES FROM WIND CLUMP BOW SHOCKS IN MASSIVE STARS

    SciTech Connect

    Ignace, R.; Waldron, W. L.; Cassinelli, J. P.; Burke, A. E. E-mail: wwaldron@satx.rr.com E-mail: burke.alexander@gmail.com

    2012-05-01

    The consequences of structured flows continue to be a pressing topic in relating spectral data to physical processes occurring in massive star winds. In a preceding paper, our group reported on hydrodynamic simulations of hypersonic flow past a rigid spherical clump to explore the structure of bow shocks that can form around wind clumps. Here we report on profiles of emission lines that arise from such bow shock morphologies. To compute emission line profiles, we adopt a two-component flow structure of wind and clumps using two 'beta' velocity laws. While individual bow shocks tend to generate double-horned emission line profiles, a group of bow shocks can lead to line profiles with a range of shapes with blueshifted peak emission that depends on the degree of X-ray photoabsorption by the interclump wind medium, the number of clump structures in the flow, and the radial distribution of the clumps. Using the two beta law prescription, the theoretical emission measure and temperature distribution throughout the wind can be derived. The emission measure tends to be power law, and the temperature distribution is broad in terms of wind velocity. Although restricted to the case of adiabatic cooling, our models highlight the influence of bow shock effects for hot plasma temperature and emission measure distributions in stellar winds and their impact on X-ray line profile shapes. Previous models have focused on geometrical considerations of the clumps and their distribution in the wind. Our results represent the first time that the temperature distribution of wind clump structures are explicitly and self-consistently accounted for in modeling X-ray line profile shapes for massive stars.

  11. Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency.

    PubMed

    Bates, John T; Keefer, Christopher J; Utley, Thomas J; Correia, Bruno E; Schief, William R; Crowe, James E

    2013-04-01

    The role of affinity in determining neutralizing potency of mAbs directed against viruses is not well understood. We investigated the kinetic, structural, and functional advantage conferred by individual naturally occurring somatic mutations in the Ab H chain V region of Fab19, a well-described neutralizing human mAb directed to respiratory syncytial virus. Comparison of the affinity-matured Ab Fab19 with recombinant Fab19 Abs that were variants containing reverted amino acids from the inferred unmutated ancestor sequence revealed the molecular basis for affinity maturation of this Ab. Enhanced binding was achieved through mutations in the third H chain CDR (HCDR3) that conferred a markedly faster on-rate and a desirable increase in antiviral neutralizing activity. In contrast, most somatic mutations in the HCDR1 and HCDR2 regions did not significantly enhance Ag binding or antiviral activity. We observed a direct relationship between the measured association rate (Kon) for F protein and antiviral activity. Modeling studies of the structure of the Ag-Ab complex suggested the HCDR3 loop interacts with the antigenic site A surface loop of the respiratory syncytial virus F protein, previously shown to contain the epitope for this Ab by experimentation. These studies define a direct relationship of affinity and neutralizing activity for a viral glycoprotein-specific human mAb.

  12. Surface directed reversible imidazole ligation to nickel(ii) octaethylporphyrin at the solution/solid interface: a single molecule level study.

    PubMed

    Nandi, Goutam; Chilukuri, Bhaskar; Hipps, K W; Mazur, Ursula

    2016-07-27

    Scanning tunneling microscopy (STM) is used to study for the first time the reversible binding of imidazole (Im) and nickel(ii) octaethylporphyrin (NiOEP) supported on highly oriented pyrolytic graphite (HOPG) at the phenyloctane/NiOEP/HOPG interface at 25 °C. The ligation of Im to the NiOEP receptor while not observed in fluid solution is readily realized at the solution/HOPG interface. The coordination process scales with increasing Im concentration and can be effectively modeled by the Langmuir isotherm. At room temperature it is determined that the standard free energy of adsorption is ΔGc = -15.8 kJ mol(-1) and the standard enthalpy of adsorption is estimated to be ΔHc ≈ -80 kJ mol(-1). The reactivity of imidazole toward NiOEP adsorbed on HOPG is attributed to charge donation from the graphite stabilizing the Im-Ni bond. This charge transfer pathway is supported by molecular and periodic modeling calculations which indicate that the Im ligand behaves as a π-acceptor. DFT calculations also show that the nickel ion in the Im-NiOEP/HOPG complex is in a singlet ground state. This is surprising since both our calculations and previous experimental studies find a triplet ground state for the five and six coordinated Im-nickel(ii) porphyrins in the gas-phase or in solution. Both the experimental and the theoretical findings provide information that is useful for better understanding of chemical sensing/recognition and catalytic processes that utilize metal-organic complexes adsorbed on surfaces where the reactivity of the metal is moderated by the substrate.

  13. Búsqueda de "bow shocks" estelares: primera versión del catálogo E-BOSS

    NASA Astrophysics Data System (ADS)

    Peri, C. S.; Benaglia, P.; Brookes, D. P.; Stevens, I. R.; Isequilla, N.

    Stellar bow shocks produced by early-type runaway stars have being stud- ied in small numbers. We developed a systematic search using the newest infrared data available. We studied one group of stars with already detected bow shocks to improve and analyse new infrared data, and also another group of OB runaway stars. We produce a catalogue of 28 bow shock can- didates, calculate some observable parameters and obtain statistics related to spectral types, velocities and mass loss rate, among others. We expect to obtain new results with, for example, the inclusion of more spectral types, and with upcoming infrared data. FULL TEXT IN SPANISH

  14. THE ROLE OF PICKUP IONS ON THE STRUCTURE OF THE VENUSIAN BOW SHOCK AND ITS IMPLICATIONS FOR THE TERMINATION SHOCK

    SciTech Connect

    Lu Quanming; Shan Lican; Zhang Tielong; Wu Mingyu; Wang Shui; Zank, Gary P.; Yang Zhongwei; Du Aimin

    2013-08-20

    The recent crossing of the termination shock by Voyager 2 has demonstrated the important role of pickup ions (PUIs) in the physics of collisionless shocks. The Venus Express (VEX) spacecraft orbits Venus in a 24 hr elliptical orbit that crosses the bow shock twice a day. VEX provides a unique opportunity to investigate the role of PUIs on the structure of collisionless shocks more generally. Using VEX observations, we find that the strength of the Venusian bow shock is weaker when solar activity is strong. We demonstrate that this surprising anti-correlation is due to PUIs mediating the Venusian bow shock.

  15. Reversal bending fatigue testing

    SciTech Connect

    Wang, Jy-An John; Wang, Hong; Tan, Ting

    2014-10-21

    Embodiments for apparatuses for testing reversal bending fatigue in an elongated beam are disclosed. Embodiments are configured to be coupled to first and second end portions of the beam and to apply a bending moment to the beam and create a pure bending condition in an intermediate portion of the beam. Embodiments are further configured to cyclically alternate the direction of the bending moment applied to the beam such that the intermediate portion of the beam cyclically bends in opposite directions in a pure bending condition.

  16. Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors

    SciTech Connect

    Su, Hua-Poo; Yan, Youwei; Prasad, G. Sridhar; Smith, Robert F.; Daniels, Christopher L.; Abeywickrema, Pravien D.; Reid, John C.; Loughran, H. Marie; Kornienko, Maria; Sharma, Sujata; Grobler, Jay A.; Xu, Bei; Sardana, Vinod; Allison, Timothy J.; Williams, Peter D.; Darke, Paul L.; Hazuda, Daria J.; Munshi, Sanjeev

    2010-09-02

    HIV/AIDS continues to be a menace to public health. Several drugs currently on the market have successfully improved the ability to manage the viral burden in infected patients. However, new drugs are needed to combat the rapid emergence of mutated forms of the virus that are resistant to existing therapies. Currently, approved drugs target three of the four major enzyme activities encoded by the virus that are critical to the HIV life cycle. Although a number of inhibitors of HIV RNase H activity have been reported, few inhibit by directly engaging the RNase H active site. Here, we describe structures of naphthyridinone-containing inhibitors bound to the RNase H active site. This class of compounds binds to the active site via two metal ions that are coordinated by catalytic site residues, D443, E478, D498, and D549. The directionality of the naphthyridinone pharmacophore is restricted by the ordering of D549 and H539 in the RNase H domain. In addition, one of the naphthyridinone-based compounds was found to bind at a second site close to the polymerase active site and non-nucleoside/nucleotide inhibitor sites in a metal-independent manner. Further characterization, using fluorescence-based thermal denaturation and a crystal structure of the isolated RNase H domain reveals that this compound can also bind the RNase H site and retains the metal-dependent binding mode of this class of molecules. These structures provide a means for structurally guided design of novel RNase H inhibitors.

  17. Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.

    PubMed

    Su, Hua-Poo; Yan, Youwei; Prasad, G Sridhar; Smith, Robert F; Daniels, Christopher L; Abeywickrema, Pravien D; Reid, John C; Loughran, H Marie; Kornienko, Maria; Sharma, Sujata; Grobler, Jay A; Xu, Bei; Sardana, Vinod; Allison, Timothy J; Williams, Peter D; Darke, Paul L; Hazuda, Daria J; Munshi, Sanjeev

    2010-08-01

    HIV/AIDS continues to be a menace to public health. Several drugs currently on the market have successfully improved the ability to manage the viral burden in infected patients. However, new drugs are needed to combat the rapid emergence of mutated forms of the virus that are resistant to existing therapies. Currently, approved drugs target three of the four major enzyme activities encoded by the virus that are critical to the HIV life cycle. Although a number of inhibitors of HIV RNase H activity have been reported, few inhibit by directly engaging the RNase H active site. Here, we describe structures of naphthyridinone-containing inhibitors bound to the RNase H active site. This class of compounds binds to the active site via two metal ions that are coordinated by catalytic site residues, D443, E478, D498, and D549. The directionality of the naphthyridinone pharmacophore is restricted by the ordering of D549 and H539 in the RNase H domain. In addition, one of the naphthyridinone-based compounds was found to bind at a second site close to the polymerase active site and non-nucleoside/nucleotide inhibitor sites in a metal-independent manner. Further characterization, using fluorescence-based thermal denaturation and a crystal structure of the isolated RNase H domain reveals that this compound can also bind the RNase H site and retains the metal-dependent binding mode of this class of molecules. These structures provide a means for structurally guided design of novel RNase H inhibitors.

  18. The Cost of Unintended Pregnancies in Canada: Estimating Direct Cost, Role of Imperfect Adherence, and the Potential Impact of Increased Use of Long-Acting Reversible Contraceptives.

    PubMed

    Black, Amanda Y; Guilbert, Edith; Hassan, Fareen; Chatziheofilou, Ismini; Lowin, Julia; Jeddi, Mark; Filonenko, Anna; Trussell, James

    2015-12-01

    Objectif : Les grossesses non planifiées (GNP) sont associées à un fardeau financier considérable; au Canada, l’ampleur de ce fardeau demeure inconnue. Cette étude avait pour objectif de quantifier les coûts directs des GNP au Canada, la proportion des coûts liés aux GNP attribuables à une observance imparfaite du schéma posologique contraceptif et les économies potentielles associées à un accroissement de l’utilisation de modes de contraception réversible à action prolongée (CRAP). Méthodes : Un modèle de coût a été conçu pour estimer le nombre annuel de GNP et leurs coûts directs chez les femmes âgées de 18 à 44 ans. Les taux de GNP associés à l’observance ont été estimés au moyen des taux d’échec de la contraception en utilisation parfaite et en utilisation typique. Les modifications du nombre annuel de GNP et les effets sur le fardeau financier ont été projetés dans le cadre de trois scénarios prévoyant un accroissement du recours aux modes de CRAP. Des analyses simples de la variance en matière de sensibilité ont été menées pour évaluer les effets de variables clés sur les scénarios prévoyant un accroissement du recours aux modes de CRAP. Résultats : On compte plus de 180 700 GNP chaque année au Canada. Les coûts directs qui leur sont associés sont de plus de 320 millions de dollars. Cinquante-huit pour cent (58 %) des GNP se sont manifestées chez des femmes de 20 à 29 ans, ce qui représente un coût annuel de 175 millions de dollars; 82 % de ce coût (143 millions de dollars) étaient attribuables à la non-observance du schéma posologique contraceptif. L’accroissement du recours aux modes de CRAP a généré des économies de plus de 34 millions de dollars dans le cadre des trois scénarios de transition envisagés; les économies les plus importantes (35 millions de dollars) ont été constatées dans le cadre du scénario prévoyant que 10 % des utilisatrices de contraceptifs

  19. Determination of the shape and orientation of nonlinear magnetic structures measured by Cluster spacecraft in the vicinity of the bow shock

    NASA Astrophysics Data System (ADS)

    Grzesiak, Marcin; Przepiórka, Dorota; Strumik, Marek; Stasiewicz, Krzysztof

    2016-03-01

    We present a new method of determination of the size and the orientation of nonlinear electromagnetic structures observed in space plasmas. The method is based on the analysis of covariance matrix of gradients of fields estimated from multipoint spacecraft measurements. It does not make use of Taylor hypothesis and gives fully three-dimensional estimates without assuming any symmetries of the structures. The method has been tested first on synthetic data and then applied to four-point Cluster spacecraft measurements to determine geometrical properties of nonlinear electromagnetic structures observed in the vicinity of the bow shock. These structures comprise ULF waves that steepen to form shocklets (short large-amplitude magnetic structures) in the foreshock region and large-amplitude mirror mode structures observed in the magnetosheath downstream of the bow shock. In the case of foreshock ULF waves we find the three-axis structure sizes of 1000, 3000, and 7000 km oriented to the ambient field at angles of 75, 30, and 60°, respectively. For the mirror modes our results give sizes of 150, 300, and 700 km oriented at angles close to the perpendicular direction for the shortest and middle scales and parallel orientation for the longest scale. The estimated geometry and properties of analyzed nonlinear structures follow, in general, those obtained previously.

  20. Direct saponification preparation and analysis of free and conjugated phytosterols in sugarcane (Saccharum officinarum L.) by reversed-phase high-performance liquid chromatography.

    PubMed

    Feng, Simin; Liu, Songbai; Luo, Zisheng; Tang, Kaichen

    2015-08-15

    A simple method based on direct saponification followed by RP-HPLC analysis was developed for quantification of free and conjugated sterols in sugarcane. Acid hydrolysis prior to alkaline saponification was used to determined acylated steryl glycoside and steryl glycoside in sugarcane. The applicability and generality of this method were improved with intensive investigation. Compared to traditional solvent extraction method, this method was more time saving and appropriate for characterization of sterol fractions in sugarcane. This method was successfully applied for determination of free and conjugated sterols in different sugarcane samples. The results exhibited that stigmasterol (varied from 883.3 ± 23.5 to 1823.9 ± 24.5 μg/g dry weigh) and β-sitosterol (varied from 117.6 ± 19.9 to 801.4 ± 33.5 μg/g dry weight) were major phytosterols in the sugarcane sample, and their glycosylated forms accounted for almost 87.0% of stigmasterol and 87.5% of β-sitosterol in sugarcane, respectively. In addition, among other parts of sugarcane, tips contained the greatest amount of phytosterols.

  1. Solar and interplanetary control of the location of the Venus bow shock

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Chou, E.; Luhmann, J. G.; Gazis, P.; Brace, L. H.; Hoegy, W. R.

    1988-01-01

    The Venus bow shock location has been measured at nearly 2000 shock crossings, and its dependence on solar EUV, solar wind conditions, and the interplanetary magnetic field determined. The shock position at the terminator varies from about 2.14 Venus radii at solar minimum to 2.40 Venus radii at solar maximum. The location of the shock varies little with solar wind dynamic pressure but strongly with solar wind Mach number. The shock is farthest from Venus on the side of the planet in which newly created ions gyrate away from the ionosphere. When the interplanetary magnetic field is perpendicular to the flow, the cross section of the shock is quite elliptical. This effect appears to be due to the anisotropic propagation of the fast magnetosonic wave. When the interplanetary magnetic field is aligned with the flow, the bow shock cross section is circular and only weakly sensitive to changing EUV flux.

  2. Half-bow sliding knot: modified suture technique for scleral fixation using the corneoscleral pocket.

    PubMed

    Chee, Soon-Phaik

    2011-09-01

    A modified suture technique for precise knot placement in the Hoffman corneoscleral pocket technique of scleral fixation is described. Both loops of the polypropylene suture passing from the intraocular device through the sclera and conjunctiva are retrieved from the pocket. A loop of suture is pulled through 3 suture throws made using the second suture loop, forming a half bow. Centration of the intraocular lens (IOL)-capsular bag is checked. If the suture tension is too tight, the surgeon can easily undo the knot of the half-bow knot by pulling it free and can then retie the sliding knot. When the IOL-capsular bag is centered, the suture loop is cut and the free end removed. The second suture end is retrieved from the pocket, and knot tying is completed without further adjustment to the tension. Posterior pressure on the intraocular device centers it and settles the knot within the sclera at the fixation point.

  3. Nonthermal ions and associated magnetic field behavior at a quasi-parallel earth's bow shock

    NASA Technical Reports Server (NTRS)

    Wilkinson, W. P.; Pardaens, A. K.; Schwartz, S. J.; Burgess, D.; Luehr, H.; Kessel, R. L.; Dunlop, M.; Farrugia, C. J.

    1993-01-01

    Attention is given to ion and magnetic field measurements at the earth's bow shock from the AMPTE-UKS and -IRM spacecraft, which were examined in high time resolution during a 45-min interval when the field remained closely aligned with the model bow shock normal. Dense ion beams were detected almost exclusively in the midst of short-duration periods of turbulent magnetic field wave activity. Many examples of propagation at large elevation angles relative to the ecliptic plane, which is inconsistent with reflection in the standard model shock configuration, were discovered. The associated waves are elliptically polarized and are preferentially left-handed in the observer's frame of reference, but are less confined to the maximum variance plane than other previously studied foreshock waves. The association of the wave activity with the ion beams suggests that the former may be triggered by an ion-driven instability, and possible candidates are discussed.

  4. The location of the subsolar bow shock of Venus - Implications for the obstacle shape

    NASA Technical Reports Server (NTRS)

    Russell, C. T.; Luhmann, J. G.; Phillips, J. L.

    1985-01-01

    The rise in periapsis altitude with time has allowed the Pioneer Venus spacecraft to begin probing the subsolar Venus bow shock. This has allowed the altitude of the subsolar bow shock to be determined by in situ observations for the first time. The observed altitude of 2280 km at the nose together with the previously determined terminator altitude can be used to infer the shape of the obstacle using the gasdynamic model of the solar wind interaction with Venus. When this shape is compared to the measured locations of the Venus ionopause (defined as the point where the magnetosheath magnetic field pressure and ionospheric thermal pressures are equal), it is found that the observed ionopause position is too low to qualify as the obstacle. It is inferred that a layer of the mass loaded plasma in the magnetosheath forms the magnetic barrier.

  5. ULF waves upstream of the Venus bow shock - Properties of one-hertz waves

    NASA Technical Reports Server (NTRS)

    Orlowski, D. S.; Russell, C. T.

    1991-01-01

    Pioneer Venus Orbiter data are used here to study the properties of a class of ULF upstream waves with relatively high observed frequencies. These waves show significant similarity to 'one-Hz' waves identified at earth in the ISEE 1 and 2 observations and the whistler waves identified earlier by IMP 6 observations. The waves appear almost immediately after the spacecraft crosses the magnetic field tangent line to the bow shock surface into the region of connected field lines. The wave amplitude decreases with distance from the shock measured along the magnetic field line. Group velocities calculated using the cold plasma dispersion relation indicate that the waves have sufficient upstream velocities to propagate form the shock into the solar wind. The totality of observations seem best explained by a source of right-handed whistler mode waves at the bow shock.

  6. Comparing vertical dimension changes with and without a face-bow transfer.

    PubMed

    Castle, A L; Anthony, T H

    1998-01-01

    The purpose of this investigation was to identify any difference of vertical dimension change that could be attributed to not using a face-bow transfer. Both demonstrations resulted in occlusal changes in vertical dimension. In comparing the demonstrations, where a hinge axis transfer was not taken, a greater amount of change was recorded over that observer in the demonstration where the hinge axis transfer was made. More dedicated research is clearly warranted to establish how much of the change was due to normal technical error. The time spent taking a face-bow transfer (hinge axis) may represent a small portion of the time required to accomplish adjustments on a denture where no transfer was performed. This information will allow the clinician to decide on the time they are willing to dedicate to occlusal corrections at the chair.

  7. Bimanual coordination of bowing and fingering in violinists--effects of position changes and string changes.

    PubMed

    Kazennikov, Oleg; Wiesendanger, Mario

    2009-07-01

    Music performance is based on demanding motor control with much practice from young age onward. We have chosen to investigate basic bimanual movements played by violin amateurs and professionals. We posed the question whether position and string changes, two frequent mechanisms, may influence the time interval bowing (right)-fingering (left) coordination. The objective was to measure bimanual coordination, i.e., with or without position changes and string changes. The tendency was that the bimanual coordination was statistically only slightly increased or even unchanged but not perceptible. We conclude that the coordination index is limited up to 100 ms intervals, without any erroneous perception. Although the mentioned position changes and string changes are movements with their timing, they are executed in parallel rather than in series with the bow-fingering coordination.

  8. Comparison of plasma wave measurements in the bow shocks at Earth, Jupiter, Saturn, Uranus and Neptune

    NASA Technical Reports Server (NTRS)

    Moses, S. L.; Coroniti, F. V.; Kennel, C. F.; Kurth, W. S.; Gurnett, D. A.

    1990-01-01

    Plasma wave measurements from the Voyager 2 crossing of Neptune's bow shock are presented and compared with measurements from the bow shocks of Earth, Jupiter, Saturn, and Uranus. The wave amplitudes above 0.01fp, when normalized to the solar wind ion thermal energy density at each planet, are significantly higher at the outer planets than at Earth. Despite the differences in amplitude, the shock spectra of all the planets can be fitted to curves of similar form in this frequency range. The total normalized electric field energy densities exhibit an exponential dependence on ion thermal Mach number, Magnetosheath wave energies are comparable at all of the planets when normalized to the downstream plasma pressure.

  9. Upstream energetic ions and electrons - Bow shock-associated or magnetospheric origin

    NASA Technical Reports Server (NTRS)

    Scholer, M.; Hovestadt, D.; Ipavich, F. M.; Gloeckler, G.

    1981-01-01

    An analysis is made of 35 proton bursts observed with the Max-Planck-Institut/University of Maryland sensor system on ISEE 3 far upstream of the earth's bow shock. These upstream bursts are found to fall into two distinctive groups. The first is accompanied by energetic electrons (more than about 75 keV), and the proton spectrum extends up to energies greater than about 300 keV and higher and bends over toward lower energies (less than about 30 keV). The second group, which is unaccompanied by energetic electron bursts, exhibits spectra which can be represented extremely well by exponentials in energy with a mean e-folding energy of approximately 15 keV. The first group is thought to be of a magnetospheric origin, and the second to be bow-shock associated.

  10. Coordination of degrees of freedom and stabilization of task variables in a complex motor skill: expertise-related differences in cello bowing.

    PubMed

    Verrel, Julius; Pologe, Steven; Manselle, Wayne; Lindenberger, Ulman; Woollacott, Marjorie

    2013-02-01

    Stringed instrument bowing is a complex sensorimotor skill, involving fine regulation of bow orientation and motion relative to the string. In this study, we characterize this skill in terms of stabilization of specific bow parameters as well as the underlying use and coordination of the degrees of freedom (DOF) of the right bowing arm. Age-matched samples of 10 advanced cellists and 10 cello novices took part in the study. Kinematic bow movement data were analyzed with respect to task variables suggested by the cello teaching literature: position and orientation of the bow relative to the string, bow velocity, and timing. Joint motion of the bowing arm was analyzed in terms of movement amplitude and inter-joint coordination (principal component analysis). As expected, novices showed poorer control of bowing parameters. In addition, novices differed markedly from advanced players in the use and coordination of the DOF of the bowing arm, with the elbow and wrist showing less overall movement and a reduced proportion of variance explained by the first principal component (PC1). In contrast, larger amounts of shoulder variance were explained by PC1 in novices compared to experts. Our findings support Bernstein's theory of graded skill acquisition, according to which early stages of motor skill learning are characterized by a "freezing" of movement DOF, while later learning stages exploit the DOF, possibly following a proximal-to-distal sequence, for improved task performance. PMID:23109087

  11. The solar cycle dependence of the location and shape of the Venus bow shock

    SciTech Connect

    Zhang, T.L.; Luhmann, J.G.; Russell, C.T. )

    1990-09-01

    From initial Pioneer Venus observations during the maximum of solar cycle 21 it was evident that the position of the Venus bow shock varies with solar activity. The bow shock radius in the terminator plane changed from 2.4 R{sub v} to 2.1 R{sub v} as solar activity went from maximum to minimum and, as activity has increased in cycle 22, it has increased again. The recent studies of the subsolar region show that the altitude of the nose of the bow shock varies from 1,600 km at solar minimum to 2,200 km at intermediate solar activity in concert with the terminator altitude so that the shape remains constant and only the size varies during the solar cycle. Using a gas dynamic model and the observed bow shock location, the authors infer the variation in the size of the effective obstacle during the solar cycle. At solar maximum, the effective obstacle is larger than the ionopause as if a magnetic barrier exists in the inner magnetosheath. This magnetic barrier acts as the effective obstacle deflecting the magnetosheath plasma about 500 km above the surface of Venus. However, at solar minimum the effective obstacle is well below the subsolar ionopause, and some absorption of the solar wind plasma by the Venus neutral atmosphere is suggested by these observations. The dependence of the solar cycle variation of the shock position on the orientation of the interplanetary magnetic field reinforces the idea that planetary ion pickup is important in the interaction of the solar wind with Venus.

  12. [A drill-bow in Horace, Odes 3.6.7].

    PubMed

    Moog, Ferdinand Peter

    2004-01-01

    With the short poem Odes 3.26 Horaces says--ostensibly--farewell to the subject of love. A symbol of his retreat is the order given to his followers: they ought to lay in the Temple of Venus the three objects which he has used in his night escapades struggling for the girls' love: lucida funalia (torches), vectis (jemmies), and arcus. The last words has been puzzling the scholars for centuries. Many took offence at the transmitted text and offered conjectures of their own. Some, however, defended arcus using different arguemtns, for instance that arcus refers to bows and arrows as weapons of the lascivious night-reveller. Also the author of this article retains arcus in the text. The context and grammatical construction let assume that also this noun denotes a tool of a burglar, preferably a drill driven by a fiddle-bow. Such instruments were use by carpenters, joiners, and surgeons. Apart from this, gigantic drill-bows were known among military machines. These were frequently applied in sieges. Horace might have seen descriptions and drawings of them in military handbooks which he presumably read in order to prepare himself for his short and rather inglorious career as an officer in the army of Caesar's murderers. For Romans without military experience who suddenly obtained a high rank at war this was a typical way of making good their shortcomings. The parallel between the siege of a town and the attack upon the beloved girl's house must be regarded as a poetic exaggeration; the reader should be amused by an impracticable idea. Furthermore, a possible connection between Horace's poem and the Heracles of Euripides is pointed out here for the first time. In Heracles 942-6 the hero, driven insane by Lyssa's work, asks for his bow, his arrows and siege instruments to take Mycenae, the fortress of his tormentor Eurystheus. In fact he brakes into his own bedroom and kills his spouse and his son.

  13. Optical Hydrogen Absorption Consistent with a Bow Shock Leading the Hot Jupiter HD 189733b

    NASA Astrophysics Data System (ADS)

    Cauley, Paul Wilson; Redfield, Seth; Jensen, Adam

    2015-08-01

    Bow shocks are ubiquitous astrophysical phenomena resulting from the supersonic passage of an object through a gas. Recently, pre-transit absorption in UV metal transitions of the hot Jupiter exoplanets HD 189733b and WASP12-b have been interpreted as being caused by material compressed in a planetary bow shock. Here we present a robust detection of a time-resolved pre-transit, as well as in-transit, absorption signature around the hot Jupiter exoplanet HD 189733b using high spectral resolution observations of several hydrogen Balmer lines. The line shape of the pre-transit feature and the shape of the time series absorption provide the strongest constraints on the morphology and physical characteristics of extended structures around an exoplanet. The in-transit measurements confirm the exospheric Hα detection of Jensen et al. (2012) although the absorption depth measured here is ~50% lower. The pre-transit absorption feature occurs 125 minutes before the predicted optical transit, a projected linear distance to the stellar disk of 7.2 Rp. The absorption strength observed in the Balmer lines indicates an optically thick, but physically small, geometry. We model this signal as the early ingress of a planetary bow shock. If the bow shock is mediated by a planetary magnetosphere, the large standoff distance derived from the model suggests a large planetary magnetic field strength. Better knowledge of exoplanet magnetic field strengths is crucial to understanding the role these fields play in star-planet interactions and protecting planets in the habitable zone from dangerous stellar flares.

  14. Serendipitous discovery of an infrared bow shock near PSR J1549–4848 with Spitzer

    SciTech Connect

    Wang, Zhongxiang; Kaplan, David L.; Slane, Patrick; Morrell, Nidia; Kaspi, Victoria M.

    2013-06-01

    We report on the discovery of an infrared cometary nebula around PSR J1549–4848 in our Spitzer survey of a few middle-aged radio pulsars. Following the discovery, multi-wavelength imaging and spectroscopic observations of the nebula were carried out. We detected the nebula in Spitzer Infrared Array Camera 8.0, Multiband Imaging Photometer for Spitzer 24 and 70 μm imaging, and in Spitzer IRS 7.5-14.4 μm spectroscopic observations, and also in the Wide-field Infrared Survey Explorer all-sky survey at 12 and 22 μm. These data were analyzed in detail, and we find that the nebula can be described with a standard bow shock shape, and that its spectrum contains polycyclic aromatic hydrocarbon and H{sub 2} emission features. However, it is not certain which object drives the nebula. We analyze the field stars and conclude that none of them can be the associated object because stars with a strong wind or mass ejection that usually produce bow shocks are much brighter than the field stars. The pulsar is approximately 15'' away from the region in which the associated object is expected to be located. In order to resolve the discrepancy, we suggest that a highly collimated wind could be emitted from the pulsar and produce the bow shock. X-ray imaging to detect the interaction of the wind with the ambient medium- and high-spatial resolution radio imaging to determine the proper motion of the pulsar should be carried out, which will help verify the association of the pulsar with the bow shock nebula.

  15. Variation of the ratio of specific heats across a detached bow shock

    NASA Technical Reports Server (NTRS)

    Chao, J. K.; Wiskerchen, M. J.

    1974-01-01

    Equations are derived which allow the ratio of specific heats behind the earth's bow shock to be evaluated if several pre-shock parameters (the specific-heat ratio, the Alfvenic Mach number, the sonic Mach number, and the angle between the shock normal at the stagnation point and the magnetic field) and the density jump across the shock are known. Numerical examples show that the dependence of the post-shock ratio on the pre-shock ratio is weak.

  16. FORMATION OF COSMIC CRYSTALS IN HIGHLY SUPERSATURATED SILICATE VAPOR PRODUCED BY PLANETESIMAL BOW SHOCKS

    SciTech Connect

    Miura, H.; Yamada, J.; Tsukamoto, K.; Nozawa, J.; Tanaka, K. K.; Yamamoto, T.; Nakamoto, T.

    2010-08-10

    Several lines of evidence suggest that fine silicate crystals observed in primitive meteorite and interplanetary dust particles (IDPs) nucleated in a supersaturated silicate vapor followed by crystalline growth. We investigated evaporation of {mu}m-sized silicate particles heated by a bow shock produced by a planetesimal orbiting in the gas in the early solar nebula and condensation of crystalline silicate from the vapor thus produced. Our numerical simulation of shock-wave heating showed that these {mu}m-sized particles evaporate almost completely when the bow shock is strong enough to cause melting of chondrule precursor dust particles. We found that the silicate vapor cools very rapidly with expansion into the ambient unshocked nebular region; for instance, the cooling rate is estimated to be as high as 2000 K s{sup -1} for a vapor heated by a bow shock associated with a planetesimal of radius 1 km. The rapid cooling of the vapor leads to nonequilibrium gas-phase condensation of dust at temperatures much lower than those expected from the equilibrium condensation. It was found that the condensation temperatures are lower by a few hundred K or more than the equilibrium temperatures. This explains the results of the recent experimental studies of condensation from a silicate vapor that condensation in such large supercooling reproduces morphologies similar to those of silicate crystals found in meteorites. Our results strongly suggest that the planetesimal bow shock is one of the plausible sites for formation of not only chondrules but also other cosmic crystals in the early solar system.

  17. Bilateral and Symmetrical Anteromedial Bowing of the Lower Limbs in a Patient with Neurofibromatosis Type-I

    PubMed Central

    Klaushofer, Klaus; Grill, Franz; Ganger, Rudolf

    2015-01-01

    An 8-year-old girl was referred to our department because of generalized bowing of long bones (radii, ulnae, and femora) and significant bilateral and symmetrical posteromedial bowing of the tibiae and fibulae. The femora were laterally bowed whereas the tibiae and fibulae showed posteromedial bowing between the middle and distal thirds of the tibia with posterior cortical thickening effectively causing the development of bilateral congenital anterolateral bowing of the tibiae and fibulae. We referred to closing-wedge osteotomy of the left tibia along with fibular osteotomy in order to realign the deformity. Due to the delayed appearance of skin stigmata in her early life, the diagnosis of neurofibromatosis was ruled out. At the age of 9 years, café-au-lait spots and axillary freckling were apparent. Genetic tests confirmed von Recklinghausen disease (neurofibromatosis type-I (NF1)) (gene has been localised to 17q22). Interestingly, bilateral and symmetrical anteromedial bowing of the tibiae and fibulae has not been described in patients with NF-I. PMID:25815222

  18. Interstellar Weather Vanes: GLIMPSE Mid-Infrared Stellar Wind Bow Shocks in M17 and RCW 49

    NASA Astrophysics Data System (ADS)

    Povich, Matthew S.; Benjamin, Robert A.; Whitney, Barbara A.; Babler, Brian L.; Indebetouw, Rémy; Meade, Marilyn R.; Churchwell, Ed

    2008-12-01

    We report the discovery of six infrared stellar wind bow shocks in the Galactic massive star formation regions M17 and RCW 49 from Spitzer GLIMPSE (Galactic Legacy Infrared Mid-Plane Survey Extraordinaire) images. The Infrared Array Camera (IRAC) on the Spitzer Space Telescope clearly resolves the arc-shaped emission produced by the bow shocks. We combine Two Micron All-Sky Survey (2MASS), Spitzer, MSX, and IRAS observations to obtain the spectral energy distributions (SEDs) of the bow shocks and their individual driving stars. We use the stellar SEDs to estimate the spectral types of the three newly identified O stars in RCW 49 and one previously undiscovered O star in M17. One of the bow shocks in RCW 49 reveals the presence of a large-scale flow of gas escaping the H II region at a few 102 km s-1. Radiation transfer modeling of the steep rise in the SED of this bow shock toward longer mid-infrared wavelengths indicates that the emission is coming principally from dust heated by the star driving the shock. The other five bow shocks occur where the stellar winds of O stars sweep up dust in the expanding H II regions.

  19. On the generation of magnetosheath high-speed jets by bow shock ripples

    PubMed Central

    Hietala, H; Plaschke, F

    2013-01-01

    [1]The terrestrial magnetosheath is embedded with coherent high-speed jets of about 1RE in scale, predominantly during quasi-radial interplanetary magnetic field (IMF). When these high dynamic pressure (Pdyn) jets hit the magnetopause, they cause large indentations and further magnetospheric effects. The source of these jets has remained controversial. One of the proposed mechanisms is based on ripples of the quasi-parallel bow shock. In this paper, we combine for the first time, 4 years of subsolar magnetosheath observations from the Time History of Events and Macroscale Interactions during Substorms mission and corresponding NASA/OMNI solar wind conditions with model calculations of a rippled bow shock. Concentrating on the magnetosheath close to the shock during intervals when the angle between the IMF and the Sun-Earth line was small, we find that (1) 97% of the observed jets can be produced by local ripples of the shock under the observed upstream conditions; (2) the coherent jets form a significant fraction of the high Pdyn tail of the magnetosheath flow distribution; (3) the magnetosheath Pdyn distribution matches the flow from a bow shock with ripples that have a dominant amplitude to wavelength ratio of about 9% (∼0.1RE/1RE) and are present ∼12% of the time at any given location. PMID:26167426

  20. Characterization of Saturn's bow shock: Magnetic field observations of quasi-perpendicular shocks

    NASA Astrophysics Data System (ADS)

    Sulaiman, A. H.; Masters, A.; Dougherty, M. K.

    2016-05-01

    Collisionless shocks vary drastically from terrestrial to astrophysical regimes resulting in radically different characteristics. This poses two complexities. First, separating the influences of these parameters on physical mechanisms such as energy dissipation. Second, correlating observations of shock waves over a wide range of each parameter, enough to span across different regimes. Investigating the latter has been restricted since the majority of studies on shocks at exotic regimes (such as supernova remnants) have been achieved either remotely or via simulations, but rarely by means of in situ observations. Here we present the parameter space of MA bow shock crossings from 2004 to 2014 as observed by the Cassini spacecraft. We find that Saturn's bow shock exhibits characteristics akin to both terrestrial and astrophysical regimes (MA of order 100), which is principally controlled by the upstream magnetic field strength. Moreover, we determined the θBn of each crossing to show that Saturn's (dayside) bow shock is predominantly quasi-perpendicular by virtue of the Parker spiral at 10 AU. Our results suggest a strong dependence on MA in controlling the onset of physical mechanisms in collisionless shocks, particularly nontime stationarity and variability. We anticipate that our comprehensive assessment will yield deeper insight into high MA collisionless shocks and provide a broader scope for understanding the structures and mechanisms of collisionless shocks.

  1. Anomalous flow deflection at planetary bow shocks in the low Alfven Mach number regime

    NASA Astrophysics Data System (ADS)

    Nishino, Masaki N.; Fujimoto, Masaki; Tai, Phan-Duc; Mukai, Toshifumi; Saito, Yoshifumi; Kuznetsova, Masha M.; Rastaetter, Lutz

    A planetary magnetosphere is an obstacle to the super-sonic solar wind and the bow shock is formed in the front-side of it. In ordinary hydro-dynamics, the flow decelerated at the shock is diverted around the obstacle symmetrically about the planet-Sun line, which is indeed observed in the magnetosheath most of the time. Here we show a case under a very low density solar wind in which duskward flow was observed in the dawnside magnetosheath of the Earth's magnetosphere. A Rankine-Hugoniot test across the bow shock shows that the magnetic effect is crucial for this "wrong flow" to appear. A full three-dimensional Magneto- Hydro-Dynamics (MHD) simulation of the situation in this previously unexplored parameter regime is also performed. It is illustrated that in addition to the "wrong flow" feature, various peculiar characteristics appear in the global picture of the MHD flow interaction with the obstacle. The magnetic effect at the bow shock should become more conspicuously around the Mercury's magnetosphere, because stronger interplanetary magnetic field and slower solar wind around the Mercury let the Alfven Mach number low. Resultant strong deformation of the magnetosphere induced by the "wrong flow" will cause more complex interaction between the solar wind and the Mercury.

  2. Spatial distribution of Langmuir waves observed upstream of Saturn's bow shock by Cassini

    NASA Astrophysics Data System (ADS)

    Píša, D.; Santolík, O.; Hospodarsky, G. B.; Kurth, W. S.; Gurnett, D. A.; Souček, J.

    2016-08-01

    We present the spatial distribution and spectral properties of Langmuir waves observed upstream of Saturn's bow shock by the Cassini spacecraft. The entire 10 kHz wideband data set obtained between June 2004 and December 2014 has been analyzed using an automated procedure. Almost 106 waveform snapshots with intense narrowband emissions in the frequency range of 1-10 kHz were detected. A typical wave spectrum exhibits a single intense peak (62% of all selected waveforms). However, spectra with a superposition of two (25%) or more (13%) intense peaks are also observed. Using magnetic field observations and a model of the bow shock, plasma wave activity across Saturn's foreshock has been mapped. The plasma wave occurrence increases steeply behind the tangent magnetic field line, i.e., the sunward foreshock boundary, and rises with increasing distance from the tangential line into the downstream region. The single peak spectra are observed across the entire foreshock, while more complicated spectra are more likely measured deeper inside the foreshock and closer to the bow shock. We confirm that the most intense waves occur close to the tangent point and decrease both deeper in the foreshock and along the tangential line.

  3. Reconstructing the Guitar: Blowing Bubbles with a Pulsar Bow Shock Backflow

    NASA Astrophysics Data System (ADS)

    van Kerkwijk, Marten H.; Ingle, Ashleigh

    2008-08-01

    The Guitar Nebula is an Hα nebula produced by the interaction of the relativistic wind of a very fast pulsar, PSR B2224+65, with the interstellar medium. It consists of a ram-pressure confined bow shock near its head and a series of semicircular bubbles further behind, the two largest of which form the body of the Guitar. We present a scenario in which this peculiar morphology is due to instabilities in the backflow from the pulsar bow shock. From simulations, these backflows appear similar to jets and their kinetic energy is a large fraction of the total energy in the pulsar's relativistic wind. We suggest that, like jets, these flows become unstable some distance downstream, leading to rapid dissipation of the kinetic energy into heat, and the formation of an expanding bubble. We show that in this scenario the sizes, velocities, and surface brightnesses of the bubbles depend mostly on observables, and that they match roughly what is seen for the Guitar. Similar instabilities may account for features seen in other bow shocks.

  4. Vocal fold bowing in elderly male monozygotic twins: a case study.

    PubMed

    Tanner, Kristine; Sauder, Cara; Thibeault, Susan L; Dromey, Christopher; Smith, Marshall E

    2010-07-01

    This case study examined case histories, diagnostic features, and treatment response in two 79-year-old male monozygotic (identical) twins with vocal fold bowing, exploring both genetic and environmental factors. DNA concordance was examined via cheek swab. Case histories, videostroboscopy, auditory- and visual-perceptual assessment, electromyography, acoustic measures, and Voice Handicap ratings were undertaken. Both twins underwent surgical intervention and subsequent voice therapy. Monozygosity was confirmed for DNA polymorphisms, with 10 of 10 concordance for STR DNA markers. For both twins, auditory- and visual-perceptual assessments indicated severe bowing, hoarseness, and breathiness, although Twin 1 was judged to be extremely severe. Differences in reference to root-mean-square amplitudes were observed for thyroarytenoid and lateral cricoarytenoid muscles, with smaller relative amplitudes observed for the Twin 1 versus Twin 2. No consistent voice improvement was observed after surgical intervention(s), despite improved mid-membranous vocal fold closure. Marked reductions in Voice Handicap Index total scores were observed after behavioral voice therapy, coinciding with increased mid-membranous and posterior laryngeal (interarytenoid) glottal closure. No substantive differences in acoustic measures were observed. Vocal fold bowing was more severe for Twin 1 versus Twin 2 despite identical heritability factors. Overall voice improvement with treatment was greater for Twin 2 than Twin 1. Environmental factors might partially account for the differences observed between the twins, including variability in their responsiveness to behavioral voice therapy. Voice therapy was useful in improving mid-membranous and posterior laryngeal closure, although dysphonia remained severe in both cases.

  5. The Bow City structure, southern Alberta, Canada: The deep roots of a complex impact structure?

    NASA Astrophysics Data System (ADS)

    Glombick, Paul; Schmitt, Douglas R.; Xie, Wei; Bown, Todd; Hathway, Ben; Banks, Christopher

    2014-05-01

    Geological and geophysical evidence is presented for a newly discovered, probable remnant complex impact structure. The structure, located near Bow City, southern Alberta, has no obvious morphological expression at surface. The geometry of the structure in the shallow subsurface, mapped using downhole geophysical well logs, is a semicircular structural depression approximately 8 km in diameter with a semicircular uplifted central region. Detailed subsurface mapping revealed evidence of localized duplication of stratigraphic section in the central uplift area and omission of strata within the surrounding annular region. Field mapping of outcrop confirmed an inlier of older rocks present within the center of the structure. Evidence of deformation along the eastern margin of the central uplift includes thrust faulting, folding, and steeply dipping bedding. Normal faults were mapped along the northern margin of the annular region. Isopach maps reveal that structural thickening and thinning were accommodated primarily within the Belly River Group. Evidence from legacy 2-D seismic data is consistent with the subsurface mapping and reveals additional insight into the geometry of the structure, including a series of listric normal faults in the annular region and complex faulting within the central uplift. The absence of any ejecta blanket, breccia, suevite, or melt sheet (based on available data) is consistent with the Bow City structure being the remnant of a deeply eroded, complex impact structure. Accordingly, the Bow City structure may provide rare access and insight into zones of deformation remaining beneath an excavated transient crater in stratified siliciclastic target rocks.

  6. Electron distributions upstream of the Comet Halley bow shock - Evidence for adiabatic heating

    NASA Technical Reports Server (NTRS)

    Larson, D. E.; Anderson, K. A.; Lin, R. P.; Carlson, C. W.; Reme, H.; Glassmeier, K. H.; Neubauer, F. M.

    1992-01-01

    Three-dimensional plasma electron (22 eV to 30 keV) observations upstream of Comet Halley bow shock, obtained by the RPA-1 COPERNIC (Reme Plasma Analyzer - Complete Positive Ion, Electron and Ram Negative Ion Measurements near Comet Halley) experiment on the Giotto spacecraft are reported. Besides electron distributions typical of the undisturbed solar wind and backstreaming electrons observed when the magnetic field line intersects the cometary bow shock, a new type of distribution, characterized by enhanced low energy (less than 100 eV) flux which peaks at 90-deg pitch angles is found. These are most prominent when the spacecraft is on field lines which pass close to but are not connected to the bow shock. The 90-deg pitch angle electrons appear to have been adiabatically heated by the increase in the magnetic field strength resulting from the compression of the upstream solar wind plasma by the cometary mass loading. A model calculation of this effect which agrees qualitatively with the observed 90-deg flux enhancements is presented.

  7. On the generation of magnetosheath high speed jets by bow shock ripples (Invited)

    NASA Astrophysics Data System (ADS)

    Hietala, H.; Plaschke, F.

    2013-12-01

    The terrestrial magnetosheath is embedded with coherent high speed jets of about 1 RE in scale, predominantly during quasi-radial interplanetary magnetic field (IMF). When these high dynamic pressure (Pdyn) jets hit the magnetopause, they cause large indentations and further magnetospheric effects. The source of these jets has remained controversial. One of the proposed mechanisms is based on ripples of the quasi-parallel bow shock. In this paper, we combine for the first time four years of subsolar magnetosheath observations from the THEMIS mission and corresponding NASA/OMNI solar wind conditions with model calculations of a rippled bow shock. Concentrating on the magnetosheath close to the shock during low IMF cone-angles, we find that (1) 97% of the observed jets can be produced by local ripples of the shock under the observed upstream conditions; (2) the coherent jets form a significant fraction of the high Pdyn tail of the magnetosheath flow distribution; (3) the magnetosheath Pdyn distribution matches the flow from a bow shock with ripples that have a dominant amplitude to wavelength ratio of about 9% (~ 0.1 RE/1 RE) and are present ~12% of the time at any given location.

  8. Bow-shock instability induced by Helmholtz resonator-like feedback in slipstream

    NASA Astrophysics Data System (ADS)

    Ohnishi, Naofumi; Sato, Yosuke; Kikuchi, Yuta; Ohtani, Kiyonobu; Yasue, Kanako

    2015-06-01

    Bow-shock instability has been experimentally observed in a low-γ flow. To clarify its mechanism, a parametric study was conducted with three-dimensional numerical simulations for specific heat ratio γ and Mach number M. A critical boundary of the instability was found in the γ-M parametric space. The bow shock tends to be unstable with low γ and high M, and the experimental demonstration was designed based on this result. The experiments were conducted with the ballistic range of the single-stage powder gun mode using HFC-134a of γ = 1.12 at Mach 9.6. Because the deformation of the shock front was observed in a shadowgraph image, the numerical prediction was validated to some extent. The theoretical estimation of vortex formation in a curved shock wave indicates that the generated vorticity is proportional to the density ratio across the shock front and that the critical density ratio can be predicted as ˜10. A strong slipstream from the surface edge generates noticeable acoustic waves because it can be deviated by the upstream flow. The acoustic waves emitted by synchronizing the vortex formation can propagate upstream and may trigger bow-shock instability. This effect should be emphasized in terms of unstable shock formation around an edged flat body.

  9. Source and Acceleration of Energetic He(+) Ions at the Earth's Bow Shock

    NASA Astrophysics Data System (ADS)

    Wang, Kemei

    1998-12-01

    This thesis have presented the first detailed study of the sources and the acceleration of energetic He+ ions in front of the Earth's bow shock, using data from AMPTE/IRM and AMPTE/CCE. the bow shock was an almost perfect perpendicular shock, we compared the results of a simulation to the observed event. The model provides a good quantitative description of the phase space distribution of the gyrating ions. A large portion (approximately 63%) of the incident pickup ions are reflected and gain energy in the interaction. It is also consistent with their spatial distribution in front of the shock. It is shown that a significant fraction of the upstream ions undergo more than one reflection at the bow shock, and gain substantial energy in this interaction. distributions of H+,/ He2+,/ He+ and O+ ions upstream of the shock, as well as a comparison of the observed spectra upstream of the shock and m the magnetosphere with results from the calculations, we concluded that He+ is locally accelerated. The subsequent modeling of the injection and diffusive acceleration at the shock presented evidence that pickup ions can be injected and accelerated more efficiently than solar wind plasma. pickup ions and anomalous cosmic rays.

  10. The solar wind interaction with Venus - Pioneer Venus observations of bow shock location and structure

    NASA Astrophysics Data System (ADS)

    Slavin, J. A.; Elphic, R. C.; Russell, C. T.; Scarf, F. L.; Wolfe, J. H.; Mihalov, J. D.; Intriligator, D. S.; Brace, L. H.; Taylor, H. A.; Daniell, R. E.

    1980-12-01

    Pioneer Venus observations are used in carrying out a study of the location and structure of the Venus bow shock. The trace of the shock in the solar wind aberrated terminator plane is almost circular at an altitude of 1.38 Venus radii independent of interplanetary magnetic field orientation with an extrapolated subsolar height of 0.38 Venus radii. Gas dynamic relations and scaling of the terrestrial analogue are used in determining the effective impenetrable obstacle altitude from the mean shock surface with the conclusion that it lies beneath the observed height of the ionopause. The short-term variability in shock position is similar to that found at the earth; over the long-term bow shock, altitude varies by up to approximately 35% in phase with the solar cycle for reasons other than changing solar wind Mach number. In contrast to ionopause position, which is shown to be well determined by external pressure measurements, it is found that bow shock altitude is only weakly dependent on ionopause height and solar wind dynamic pressure.

  11. Reverse pupillary block associated with pigment dispersion syndrome after in-the-bag intraocular lens implantation.

    PubMed

    Itagaki, Hideo; Kunikata, Toshio; Hiratsuka, Kentaro; Saito, Junichiro; Oshika, Tetsuro

    2013-12-01

    A 61-year-old man with high myopia who had received a systemic α1A-adrenoceptor antagonist had phacoemulsification and in-the-bag intraocular lens implantation in the right eye. One day postoperatively, marked pigment dispersion in the anterior chamber, posterior bowing of the iris, and iridodonesis were noted associated with a subsequent elevation in intraocular pressure (IOP). Pharmacological pupil dilation was effective in reducing pigment dispersion and IOP, and laser peripheral iridotomy was performed to alleviate posterior bowing of the iris. We hypothesize that dynamic changes in the aqueous humor flow by cataract surgery and latent flaccidity of the iris due to the systemic α1A-adrenoceptor antagonist caused reverse pupillary block. High myopia may be another risk factor for this complication. PMID:24140374

  12. THE BALMER-DOMINATED BOW SHOCK AND WIND NEBULA STRUCTURE OF {gamma}-RAY PULSAR PSR J1741-2054

    SciTech Connect

    Romani, Roger W.; Shaw, Michael S.; Camilo, Fernando; Cotter, Garret; Sivakoff, Gregory R. E-mail: msshaw@stanford.ed

    2010-12-01

    We have detected an H{alpha} bow shock nebula around PSR J1741-2054, a pulsar discovered through its GeV {gamma}-ray pulsations. The pulsar is only {approx}1.''5 behind the leading edge of the shock. Optical spectroscopy shows that the nebula is non-radiative, dominated by Balmer emission. The H{alpha} images and spectra suggest that the pulsar wind momentum is equatorially concentrated and implies a pulsar space velocity {approx}150 km s{sup -1}, directed 15{sup 0} {+-} 10{sup 0} out of the plane of the sky. The complex H{alpha} profile indicates that different portions of the post-shock flow dominate line emission as gas moves along the nebula and provide an opportunity to study the structure of this unusual slow non-radiative shock under a variety of conditions. CXO ACIS observations reveal an X-ray pulsar wind nebula within this nebula, with a compact {approx}2.''5 equatorial structure and a trail extending several arcminutes behind. Together these data support a close ({<=}0.5 kpc) distance, a spin geometry viewed edge-on, and highly efficient {gamma}-ray production for this unusual, energetic pulsar.

  13. Taking a bow in the theater of things.

    PubMed

    Wintroub, Michael

    2010-12-01

    Beginning with the meaning and use of the word "performance," this essay analyzes some of the ambiguities and tensions performance has historically engendered. These tensions were both social and epistemic and can be sketched out with relation to either the corrupting influences of performance as dissimulation and masquerade or its didactic possibilities as exemplary of morality, virtue, and truth. Following these tensions across the history of antitheatrical literature into early modern natural philosophy, the essay attempts to show some of the ways that natural philosophy was used to perform--regulate, discipline, and direct--its audience(s), while simultaneously being itself performed-through interlocking practices enacted by sites, objects, and humans--as demonstrative of the legitimacy of its social and epistemic authority. PMID:21409986

  14. Effect of an isotropic outflow from the Galactic Centre on the bow-shock evolution along the orbit

    NASA Astrophysics Data System (ADS)

    Zajaček, M.; Eckart, A.; Karas, V.; Kunneriath, D.; Shahzamanian, B.; Sabha, N.; Mužić, K.; Valencia-S., M.

    2016-01-01

    Motivated by the observations of several infrared-excess bow-shock sources and proplyd-like objects near the Galactic Centre, we analyse the effect of a potential outflow from the centre on bow-shock properties. We show that due to the non-negligible isotropic central outflow the bow-shock evolution along the orbit becomes asymmetric between the pre-peribothron and post-peribothron phases. This is demonstrated by the calculation of the bow-shock size evolution, the velocity along the shocked layer, the surface density of the bow shock, and by emission-measure maps close to the peribothron passage. Within the ambient velocity range of ≲2000 km s-1 the asymmetry is profound and the changes are considerable for different outflow velocities. As a case study we perform model calculations for the Dusty S-cluster Object (DSO/G2) as a potential young stellar object that is currently being monitored and has passed the pericentre at ˜2000 Schwarzschild radii from the supermassive black hole (Sgr A*) in 2014. We show that the velocity field of the shocked layer can contribute to the observed increasing line width of the DSO source up to the peribothron. Subsequently, supposing that the line emission originates in the bow shock, a decrease of the line width is expected. Furthermore, the decline of the bow-shock emission measure in the post-peribothron phase could help to reveal the emission of the putative star. The dominant contribution of circumstellar matter (either inflow or outflow) is consistent with the observed stable luminosity and compactness of the DSO/G2 source during its pericentre passage.

  15. Process of forming compounds using reverse micelle or reverse microemulsion systems

    DOEpatents

    Linehan, John C.; Fulton, John L.; Bean, Roger M.

    1998-01-01

    The present invention is directed to a process for producing a nanometer-sized metal compound. The process comprises forming a reverse micelle or reverse microemulsion system comprising a polar fluid in a non-polar or low-polarity fluid. A first reactant comprising a multi-component, water-soluble metal compound is introduced into the polar fluid in a non-polar or low-polarity fluid. This first reactant can be introduced into the reverse micelle or reverse microemulsion system during formation thereof or subsequent to the formation of the reverse micelle or microemulsion system. The water-soluble metal compound is then reacted in the reverse micelle or reverse microemulsion system to form the nanometer-sized metal compound. The nanometer-sized metal compound is then precipitated from the reverse micelle or reverse microemulsion system.

  16. Time-reversed, flow-reversed ballistics simulations

    SciTech Connect

    Zernow, L.; Chapyak, E. J.; Scheffler, D. R.

    2001-01-01

    Two-dimensional simulations of planar sheet jet formation are studied to examine the hydrodynamic issues involved when simulations are carried out in the inverse direction, that is, with reversed time and flow. Both a realistic copper equation of state and a shockless equation of state were used. These studies are an initial step in evaluating this technique as a ballistics design tool.

  17. Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression

    PubMed Central

    Watari, Hidemichi; Hanley, Sharon J.B.; Yamada, Takahiro; Hosaka, Masayoshi; Kudo, Masataka; Yue, Junming; Sakuragi, Noriaki

    2016-01-01

    Overexpression of IQGAP1 and microRNA (miRNA) dysregulation are frequent in human tumors, but little is known about the role of IQGAP1 and its relationship to miRNA in endometrial carcinogenesis. We demonstrate that IQGAP1 activates the epithelial–mesenchymal transition (EMT) program and that miR-124 directly represses IQGAP1 expression in endometrial cancer (EC) cells. The overexpression of IQGAP1 stimulates EMT features and enhances migration, invasion and proliferation of EC cells, whereas knocking down IQGAP1 expression reverses EMT and inhibits these malignant properties. Using miRNA microarray profiling, we identified 29 miRNAs (let-7b, let-7f, miR-10b, miR-15b, miR-23a, miR-24, miR-25, miR-27a, miR-29b, miR-30a-5p, miR-34a, miR-124, miR-127, miR-130b, miR-148a, miR-155, miR-191*, miR-194, miR-224, miR-362, miR-409-3p, miR-422b, miR-424, miR-453, miR-497, miR-518d, miR-518f*, miR-526a and miR-656) that are significantly down-regulated in an in vitro-selected highly invasive derivative cell line (HEC-50-HI) relative to the parental HEC-50 cells. We further identified miR-124 as a direct regulator of IQGAP1 in EC cells. Enforced expression of miR-124 suppresses EC cell invasion and proliferation. The expression of IQGAP1 mRNA was significantly elevated in EC tissues, while the expression of miR-124 was decreased. The downregulation of miR-124 correlates with a poor survival outcome for patients with EC. Treating EC cells with the demethylating agent 5-aza-2′-deoxycytidine increased miR-124 expression and down-regulated IQGAP1 levels. Our data suggest that IQGAP1 promotes EMT, migration and invasion of EC cells. MiR-124, a novel tumor suppressor miRNA that is epigenetically silenced in EC, can reverse EMT and the invasive properties, by attenuating the expression of the IQGAP1 oncogene. PMID:26934121

  18. Observational test of shock drift and Fermi acceleration on a seed particle population upstream of earth's bow shock

    NASA Technical Reports Server (NTRS)

    Anagnostopoulos, G. C.; Sarris, E. T.; Krimigis, S. M.

    1988-01-01

    The efficiency of proposed shock acceleration mechanisms as they operate at the bow shock in the presence of a seed energetic particle population was examined using data from simultaneous observations of energetic solar-origin protons, carried out by the IMP 7 and 8 spacecraft in the vicinity of the quasi-parallel (dawn) and quasi-perpendicular (dusk) regions of the earth's bow shock, respectively. The results of observations (which include acceleration effects in the intensities of the energetic protons with energies as high as 4 MeV observed at the vicinity of the dusk bow shock, but no evidence for any particle acceleration at the energy equal to or above 50 keV at the dawn side of the bow shock) indicate that the acceleration of a seed particle population occurs only at the quasi-perpendicular bow shock through shock drift acceleration and that the major source of observed upstream ion populations is the leakage of magnetospheric ions of energies not less than 50 keV, rather than in situ acceleration.

  19. Vocal Fold Bowing in Elderly Male Monozygotic Twins: A Case Study

    PubMed Central

    Tanner, Kristine; Sauder, Cara; Thibeault, Susan L.; Dromey, Christopher; Smith, Marshall E.

    2009-01-01

    Objectives This study examined case histories, diagnostic features, and treatment response in two 79-year-old male monozygotic (identical) twins with vocal fold bowing, exploring both genetic and environmental factors. Study Design Case study. Methods DNA concordance was examined via cheek swab. Case histories, videostroboscopy, auditory- and visual-perceptual assessment, electromyography, acoustic measures, and Voice Handicap ratings were undertaken. Both twins underwent surgical intervention and subsequent voice therapy. Results Monozygosity was confirmed for DNA polymorphisms, with 10 of 10 concordance for STR DNA markers. For both twins, auditory and visual-perceptual assessments indicated severe bowing, hoarseness and breathiness, although Twin 1 was judged to be extremely severe. Differences in RMS amplitudes were observed for TA and LCA muscles, with smaller relative amplitudes observed for the Twin 1 versus Twin 2. No consistent voice improvement was observed following surgical intervention(s), despite improved mid-membranous vocal fold closure. Marked reductions in Voice Handicap Index total scores were observed following behavioral voice therapy, coinciding with increased mid-membranous and posterior laryngeal (interarytenoid) glottal closure. No substantive differences in acoustic measures were observed. Conclusions Vocal fold bowing was more severe for Twin 1 versus Twin 2 despite identical heritability factors. Overall voice improvement with treatment was greater for Twin 2 than Twin 1. Environmental factors might partially account for the differences observed between the twins, including variability in their responsiveness to behavioral voice therapy. Voice therapy was useful in improving mid-membranous and posterior laryngeal closure, although dysphonia remained severe in both cases. PMID:19664899

  20. Astrophysically relevant radiatively cooled hypersonic bow shocks in nested wire arrays

    NASA Astrophysics Data System (ADS)

    Ampleford, David

    2009-11-01

    We have performed laboratory experiments which introduce obstructions into hypersonic plasma flows to study the formation of shocks. Astrophysical observations have demonstrated many examples of equivalent radiatively cooled bow shocks, for example the head of protostellar jets or supernova remnants passing through the interstellar medium or between discrete clumps in jets. Wire array z-pinches allow us to study quasi-planar radiatively cooled flows in the laboratory. The early stage of a wire array z-pinch implosion consists of a steady flow of the wire material towards the axis. Given a high rate of radiative cooling, these flows reach high sonic- Mach numbers, typically up to 5. The 2D nature of this configuration allows the insertion of obstacles into the flow, such as a concentric ``inner'' wire array, as has previously been studied for ICF research. Here we study the application of such a nested array to laboratory astrophysics where the inner wires act as obstructions perpendicular to the flow, and induce bow shocks. By varying the wire array material (W/Al), the significance of radiative cooling on these shocks can be controlled, and is shown to change the shock opening angle. As multiple obstructions are present, the experiments show the interaction of multiple bow shocks. It is also possible to introduce a magnetic field around the static object, increasing the opening angle of the shocks. Further experiments can be designed to control the flow density, magnetic field structure and obstruction locations. In collaboration with: S.V. Lebedev, M.E. Cuneo, C.A. Jennings, S.N. Bland, J.P. Chittenden, A. Ciardi, G.N. Hall, S.C. Bott, M. Sherlock, A. Frank, E. Blackman

  1. Comparison of picked-up protons and water group ions upstream of Comet Halley's bow shock

    NASA Technical Reports Server (NTRS)

    Neugebauer, M.; Coates, A. J.; Neubauer, F. M.

    1990-01-01

    The similarities and differences between the picked-up cometary protons and water-group (WG) ions upstream of the bow shock of Comet Halley are examined using measurements obtained by the ion mass spectrometer and plasma analyzer experiments on board Giotto. It was found that the dependencies of the pitch angle and the energy diffusion rates of the cometary protons and WG ions on the ion densities and on the angle alpha between the interplanetary field and the solar wind velocity vector were very different. This finding could not be explained in terms of presently available theories and models.

  2. Heavy Solar Wind Ion Dynamics at and Downstream from the Bow Shock

    NASA Technical Reports Server (NTRS)

    Dougherty, Virginia M.

    1997-01-01

    This is a contract under the NASA Supporting Research and Technology Program for the analysis and interpretation of the scientific data from the Plasma Composition Experiment on the International Sun Earth Explorer 1 (ISEE-1) spacecraft and the Fast Plasma Experiment on the ISEE-1 and -2 spacecraft. These combined data sets will be used in a comprehensive study of the heavy solar wind ion dynamics at and downstream from the Earth's bow shock. The report summarizes activities during the above period and outlines expected activities during the forthcoming quarter.

  3. Analysis of the spectral energy distribution from a runaway star bow shock

    NASA Astrophysics Data System (ADS)

    Peri, C. S.; Araudo, A. T.; Benaglia, P.; Romero, G. E.; Martí, J.

    2011-10-01

    The bow shock produced by the high-mass runaway star BD +43° 3654 (Comerón & Pasquali 2007) has been detected as a non-thermal radio source (S_ν ∝ ν^{-α}, <α>=0.5) and it is the first one of that type ever observed (Benaglia et al. 2010). The non-thermal detection provides evidence of the presence of a magnetic field and relativistic electrons. This population of relativistic particles can produce high-energy (HE) emission.

  4. Planetary Evaporation and the Dynamics of Planet Wind/Stellar Wind Bow Shocks

    NASA Astrophysics Data System (ADS)

    Frank, A.; Lui, B.; Carroll-Nellenback, J.; Quillen, A. C.; Blackman, E. G.; Kasting, J.; Dobbs-Dixon, I.

    2016-01-01

    We present initial results of a new campaign of simulations focusing on the interaction of planetary winds with stellar environments using Adaptive Mesh Refinement methods. We have confirmed the results of Stone & Proga (2009) that an azimuthal flow structure is created in the planetary wind due to day/night temperatures differences. We show that a backflow towards the planet will occur with a strength that depends on the escape parameter. When a stellar outflow is included, we see unstable bow waves forming through the outflow's interaction with the planetary wind.

  5. Coherence of coactivation and acceleration in task-specific primary bowing tremor.

    PubMed

    Lee, André; Tominaga, Kenta; Furuya, Shinichi; Miyazaki, Fumio; Altenmüller, Eckart

    2014-07-01

    Coherences between coactivation of wrist antagonist muscles and movement fluctuation were assessed in four violinists with a task-specific tremor and four age-matched healthy violinists using electromyography and accelerometer. We found coherence between individual muscular activation and tremor only in patients at a frequency range of 3-8 Hz. The finding corroborates the notion that primary bowing tremor emerges mainly due to central neurogenic contributions via motor-unit synchronization. Furthermore, the coherence between the muscular coactivation and tremor suggests a relation of the tremor to dystonia.

  6. Near-Field Enhanced UV Resonance Raman Spectroscopy Using Aluminum Bow-tie Nano-antenna

    SciTech Connect

    Li, Ling; Lim, Shuang Fang; Puretzky, Alexander A; Riehn, Robert; Hallen, Hans

    2012-01-01

    An aluminum bow-tie nano-antenna is combined with the resonance Raman eect in the deep ultraviolet to dramatically increase the sensitivity of Raman spectra to a small volume of material, such as benzene used here. We further demonstrate gradient-eld Raman peaks for several strong IR modes. We achieve a gain of 105 in signal intensity from the near eld enhancement due to the surface plasmon resonance in the aluminum nanostructure. The on-line resonance enhancement contributes another factor of several thousands, limited by the laser line width. Thus, an overall gain of hundreds of million is achieved.

  7. Broadband millimeter-wave GaAs transmitters and receivers using planar bow-tie antennas

    NASA Technical Reports Server (NTRS)

    Konishi, Y.; Kamegawa, M.; Case, M.; Yu, R.; Rodwell, M. J. W.; York, R. A.; Rutledge, D. B.

    1992-01-01

    We report broadband monolithic transmitters and receivers IC's for mm-wave electromagnetic measurements. The IC's use nonlinear transmission lines (NLTL) and sampling circuits as picosecond pulse generators and detectors. The pulses are radiated and received by planar monolithic bow-tie antennas, collimated with silicon substrate lenses and off-axis parabolic reflectors. Through Fourier transformation of the received pulse, 30-250 GHz free space gain-frequency measurements are demonstrated with an accuracy approximately = 0.17 dB, RMS.

  8. Plasma wave system measurements of the Martian bow shock from the Phobos 2 spacecraft

    SciTech Connect

    Trotignon, J.G. ); Grard, R. ); Savin, S. )

    1991-07-01

    The high-resolution data of the electric field observations performed by the plasma wave system (PWS) during some of the Martian bow shock intersections by Phobos 2 were analyzed. Plasma and wave detectors are very useful instruments for locating the shock transition region and studying structures in the upstream region, such as the foot or the electron foreshock. The electron plasma oscillations that develop in the latter give access to the plasma density of the solar wind. Shock surface models derived from the PWS data are compared to those obtained by other authors, and attention is paid to similarities and differences between the electric field measurements obtained for Mars, Venus, and Earth

  9. Direct quantification of mRNA and miRNA from cell lysates using reverse transcription real time PCR: a multidimensional analysis of the performance of reagents and workflows.

    PubMed

    Ho, Yoon Khei; Xu, Wen Ting; Too, Heng Phon

    2013-01-01

    Substantial efforts have been devoted to in vitro testing of candidate chemotherapeutics by profiling transcriptional changes across the collection of NCI-60 cell-lines. A work-flow with reagents that enable the direct quantification of RNA of different molecular sizes simultaneously in the same sample without laborious total RNA isolation will invariably increase the throughput and accuracy of the study. MicroRNAs (miRNAs) are known to regulate most cellular functions, acting post-transcriptionally by repressing numerous eukaryotic mRNAs. Recent findings on the remarkable stability of miRNA prompted us to investigate the feasibility of quantifying the expression levels of both mRNA and miRNA directly from cell lysates (cell-to-Ct). Multidimensional analyses of the expressions of mRNA and miRNA across seven NCI-60 cell lines and multiple reagents were conducted to assess the performances of these reagents and workflows for cell-to-Ct measurements using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Quantification of RNA species using lysates prepared from an in-house and one of the commercial reagents demonstrated comparable performance to those prepared by the more laborious and conventional method of using guanidinium-phenol-chloroform. Additionally, miRNA was found to be highly stable in the cell lysates when incubated at room temperature for prolonged period of time and subjected to multiple freeze-thaw cycles. In summary, this study demonstrated significant differences in pre-analytical performance of a variety of commercially available reagents and described a cost-effective reagent useful for rapid, scalable, and high-throughput workflow for the detection of mRNA and miRNA from the same biological sample.

  10. Dynamics and timing of reversals

    NASA Astrophysics Data System (ADS)

    Valet, J.-P.; Fournier, A.

    2012-04-01

    Information provided by records of geomagnetic reversals from lava sequences is constrained by irregular volcanic activity. We show that, despite different resolution, the ten most detailed volcanic records match surprisingly well and display the same dynamical characteristics after tuning to a common eruption rate. We thus infer that the reversal process has remained unchanged over the past 180Ma with the same time constants and duration. The reversing field is characterized by 3 successive episodes, a precursory event, a 180° polarity switch and a rebound. The first and third phases depict a large amplitude directional change which, by comparison with the archeological record, is estimated to last between 2 and 2.5 kyr. The transit between the two polarities does not exceed 1ka and is thus too fast for being properly recorded by most sediments. Similar results are obtained after reducing the directional clusters that are present at different periods in each record. These features and time constants are compatible with models that do not require any mantle control on reversals processes, which is also supported by the absence of preferred longitude of the pole. Lastly, based on the chronology of the successive reversal phases, the eruption rates are found to be at least twice larger for hot spots (<1flow/100yr) than for large flood basaltic provinces.

  11. [Development Of 25-Year Imp 8 Bow Shock Crossing "List, Ingestion Of This List To Cdaweb, & Enhancement"

    NASA Technical Reports Server (NTRS)

    Merka, J.; Szabo, A.; Narock, T. W.; King, J. H.; Paularena, K. I.; Richardson, J. D.

    2003-01-01

    The MIT portion of this project was to use the plasma data from IMP 8 to identify bow shock crossings for construction of a bow shock data base. In collaboration with Goddard, we determined which shock parameters would be included in the catalog and developed a set of flags for characterizing the data. IMP 8 data from 1973-2001 were surveyed for bow shock crossings; the crossings apparent in the plasma data were compared to a list of crossing chosen in the magnetometer data by Goddard. Differences were reconciled to produce a single list. The data were then provided to the NSSDC for archiving. All the work ascribed to MIT in the proposal was completed.

  12. Characteristics of spectra from the Martian bow shock and comparison with Venus, Earth, AMPTE, Jupiter, and Saturn

    SciTech Connect

    Moses, S.L. TRW Space and Technology Group, Redondo Beach, CA ); Kennel, C.F.; Strangeway, R.J. ); Grard, R.; Nairn, C. )

    1991-07-01

    The authors present plasma wave spectra from crossings of the Martian bow shock by the Phobos 2 spacecraft and compare them with spectra from bow shocks at other planets and the AMPTE lithium release. They find that the shock spectra of the inner planets are very similar in shape, and their wave energy densities, when normalized to the upstream electron thermal energy density, are comparable. However, the Martian shock spectrum most resembles the spectrum from AMPTE, which may indicate either the presence of pickup particles or processes involving ions with gyroradii that are large compared with the size of the interaction region. The normalized wave amplitudes at Mars are midway between the high normalized amplitudes found at Jupiter and Saturn and the lower, normalized amplitudes at Earth. This is consistent with a trend that has recently been shown to occur out to Neptune's bow shock.

  13. Comparison of theory with atomic oxygen 130.4 nm radiation data from the Bow Shock ultraviolet 2 rocket flight

    NASA Technical Reports Server (NTRS)

    Levin, Deborah A.; Candler, Graham V.; Collins, Robert J.; Howlett, Carl L.; Espy, Patrick; Whiting, Ellis; Park, Chul

    1993-01-01

    Comparison is made between the results obtained from a state-of-the-art flow and radiative model and bow shock vacuum ultraviolet (VUV) data obtained the recent Bow Shock 2 Flight Experiment. An extensive data set was obtained from onboard rocket measurements at a reentry speed of 5 km/sec between the altitudes of approximately 65-85 km. A description of the NO photoionization cell used, the data, and the interpretation of the data will be presented. The primary purpose of the analyses is to assess the utility of the data and to propose a radiation model appropriate to the flight conditions of Bow Shock 2. Theoretical predictions based on flow modeling discussed in earlier work and a new radiation model are compared with data.

  14. Multicentre randomised double bind crossover trial on contamination of conventional ties and bow ties in routine obstetric and gynaecological practice.

    PubMed Central

    Biljan, M M; Hart, C A; Sunderland, D; Manasse, P R; Kingsland, C R

    1993-01-01

    OBJECTIVE--To assess level of contamination of neckwear worn by gynaecologists and obstetricians during routine working week. DESIGN--Multicentre randomised double blind crossover trial. Participants wore the same conventional ties for three days in one week and bow ties for the same period in second week. SETTING--Two teaching and three district general hospitals in the midlands, Wales, and north England. SUBJECTS--15 registrars and senior registrars. INTERVENTIONS--A swab soaked in sterile saline was taken from specific area on ties at end of first and third working days and sent in transport medium for culture on chocolatised blood and MacConkey agar for 48 hours. MAIN OUTCOME MEASURES--Level of bacteriological growth assessed semiquantitatively (0 for no contamination; for heavy contamination) after swabs had been cultured. At end of study the participants completed a questionnaire to assess their attitude toward wearing different types of necktie. RESULTS--12 doctors (80%) completed the study. Although bow ties were significantly less contaminated at end of first working day (z = -2.354, p = 0.019), this difference was not maintained; there was no difference in level of contamination on third day. Level of contamination did not increase between first and third day of wearing the same garment. One of the 10 doctors who returned the questionnaire found the bow tie very uncomfortable. All participants would consider wearing a bow tie if it proved to be less contaminated than a conventional tie. CONCLUSIONS--Although a significant difference in contamination was established between conventional and bow ties on first day of study, this difference was not confirmed on third day and there is unlikely to be any real association between tie type and bacterial contamination. Because of its negative image and difficulty to tie, the bow tie will probably remain a minority fashion. Images p1583-a PMID:8292945

  15. Reversible logic gates on Physarum Polycephalum

    SciTech Connect

    Schumann, Andrew

    2015-03-10

    In this paper, we consider possibilities how to implement asynchronous sequential logic gates and quantum-style reversible logic gates on Physarum polycephalum motions. We show that in asynchronous sequential logic gates we can erase information because of uncertainty in the direction of plasmodium propagation. Therefore quantum-style reversible logic gates are more preferable for designing logic circuits on Physarum polycephalum.

  16. Stagnation point reverse flow combustor

    NASA Technical Reports Server (NTRS)

    Zinn, Ben T. (Inventor); Neumeier, Yedidia (Inventor); Seitzman, Jerry M. (Inventor); Jagoda, Jechiel (Inventor); Weksler, Yoav (Inventor)

    2008-01-01

    A method for combusting a combustible fuel includes providing a vessel having an opening near a proximate end and a closed distal end defining a combustion chamber. A combustible reactants mixture is presented into the combustion chamber. The combustible reactants mixture is ignited creating a flame and combustion products. The closed end of the combustion chamber is utilized for directing combustion products toward the opening of the combustion chamber creating a reverse flow of combustion products within the combustion chamber. The reverse flow of combustion products is intermixed with combustible reactants mixture to maintain the flame.

  17. Recent H-alpha Results on Pulsar B2224+65's Bow-Shock Nebula, the "Guitar"

    NASA Astrophysics Data System (ADS)

    Dolch, Timothy; Chatterjee, Shami; Clemens, Dan P.; Cordes, James M.; Cashmen, Lauren R.; Taylor, Brian W.

    2016-09-01

    We used the 4 m Discovery Channel Telescope (DCT) at Lowell observatory in 2014 to observe the Guitar Nebula, an Hα bow-shock nebula around the high-velocity radio pulsar B2224+65. Since the nebula's discovery in 1992, the structure of the bow-shock has undergone significant dynamical changes. We have observed the limb structure, targeting the “body” and “neck” of the guitar. Comparing the DCT observations to 1995 observations with the Palomar 200-inch Hale telescope, we found changes in both spatial structure and surface brightness in the tip, head, and body of the nebula.

  18. High-order harmonics from bow wave caustics driven by a high-intensity laser

    SciTech Connect

    Pirozhkov, A.S.; Kando, M.; Esirkepov, T.Zh.; and others

    2012-07-11

    We propose a new mechanism of high-order harmonic generation during an interaction of a high-intensity laser pulse with underdense plasma. A tightly focused laser pulse creates a cavity in plasma pushing electrons aside and exciting the wake wave and the bow wave. At the joint of the cavity wall and the bow wave boundary, an annular spike of electron density is formed. This spike surrounds the cavity and moves together with the laser pulse. Collective motion of electrons in the spike driven by the laser field generates high-order harmonics. A strong localization of the electron spike, its robustness to oscillations imposed by the laser field and, consequently, its ability to produce high-order harmonics is explained by catastrophe theory. The proposed mechanism explains the experimental observations of high-order harmonics with the 9 TW J-KAREN laser (JAEA, Japan) and the 120 TW Astra Gemini laser (CLF RAL, UK) [A. S. Pirozhkov, et al., arXiv:1004.4514 (2010); A. S. Pirozhkov et al, AIP Proceedings, this volume]. The theory is corroborated by high-resolution two-and three-dimensional particle-in-cell simulations.

  19. COSTEP/SOHO observations of energetic electrons far upstream of the Earth's bow-shock

    NASA Astrophysics Data System (ADS)

    Klassen, A.; Gómez-Herrero, R.; Böhm, E.; Müller-Mellin, R.; Heber, B.; Wimmer-Schweingruber, R.

    2008-05-01

    We have analyzed 124 electron bursts at energies above 0.25 MeV observed with the EPHIN/COSTEP instrument onboard the SOHO spacecraft far upstream of the Earth's bow-shock at the libration point L1 from 1996 through 2005. Most of the bursts were observed during low solar activity (in 1996-1997 and in 2005) and all 124 bursts were not associated with solar particle events. It is shown that some upstream events are detected at energies above 0.7 MeV. We find that the event occurrence number shows a distinct seasonal variation with maxima around equinoxes and minima near solstices. This together with a close correspondence between the event occurrence number with maxima in solar wind speed (Vsw), geomagnetic activity index (Ap) and in the southward interplanetary magnetic field (IMF) component (Bz) indicates that the observed events can be explained in terms of leakage of magnetospheric particles during enhanced geoactivity rather than by acceleration at the Earth's bow-shock.

  20. Wave and ion evolution downstream of quasi-perpendicular bow shocks

    NASA Technical Reports Server (NTRS)

    Mckean, M. E.; Omidi, N.; Krauss-Varban, D.

    1995-01-01

    Distribution functions of ions heated in quasi-perpendicular bow shocks have a large perpendicular temperature anisotropy that provides free energy for the growth of Alfven ion cyclotron (AIC) waves and mirror waves. Both types of waves have been observed in the Earth's magnetosheath downstream of quasi-perpendicular shocks. We use a two-dimensional hybrid simulations to give a self-consistent description of the evolution of the wave spectra downstream of quasi-perpendicular shocks. Both mirror and AIC waves are identified in the simulated magnetosheath. They are generated at or near the shock front and convected away from it by the sheath plasma. Near the shock, the waves have a broad spectrum, but downstream of the shock, shorter-wavelength modes are heavily damped and only longer-wavelength modes persist. The characteristics of these surviving modes can be predicted with reasonable accuracy by linear kinetic theory appropriate for downstream conditions. We also follow the evolution of the ion distribution function. The shocked ions that provide the free energy for wave growth have a two-component distribution function. The halo is initially gyrophase-bunched and extremely anisotropic. Within a relatively short distance downstream of the shock (of the order of 10 ion inertial lengths), wave-particle interactions remove these features from the halo and reduce the anisotropy of the distribution to near-threshold levels for the mirror and AIC instabilities. A similar evolution has been observed for ions at the Earth's bow shock.