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Sample records for brazoria county tx

  1. Influence of Changing Hydrology on Pedogenic Calcite Precipitation in Vertisols, Dance Bayou, Brazoria County, Tx: Implications for Estimating Paleoatmospheric PCO2

    NASA Astrophysics Data System (ADS)

    Mintz, J. S.; Driese, S. G.; Ludvigson, G. A.; Breecker, D. O.

    2010-12-01

    Pedogenic (soil formed) calcites preserved in the sedimentary record enable estimation of paleoatmospheric pCO2 using the calcite paleobarometer. A fundamental assumption for applying this paleobarometer is that the calcite precipitated while the soil was in communication with the atmosphere so that atmospheric CO2 concentrations had a direct influence on the calcite δ13C value. Here we address the timing of calcite precipitation in relation to the soil saturation state and atmosphere connectivity in a modern Vertisol (smectitic, clay-rich soil, seasonally saturated) in Brazoria County, Texas. Luminescent phases of calcite growth have more negative δ13C values (avg. δ13C = -11.1 ‰ PDB) than the non-luminescent phases (avg. δ13C = -2.8 ‰ PDB). The luminescent phase formed during the water-saturated portion of the year limiting the soil connectivity with the atmosphere, minimizing the incorporation of atmospheric CO2 and negating its use for pCO2 estimations. The non-luminescent phase formed during the well-drained portion of the year when atmospheric CO2 mixed with soil-respired CO2 and is therefore useful for pCO2 estimation. From these results we present a model to independently test the saturation state of a paleosol at the time of pedogenic carbonate precipitation. Finally we calculate soil respiration rates that are an order of magnitude lower than those that are typically assumed in the paleobarometer equation. Many of the pCO2 estimates through the Phanerozoic are based on carbonate in paleo-Vertisols and may therefore be overestimated or potentially invalid. A) Comparisons of typical morphotype isotope values with interpreted soil conditions at the time of calcite precipitation. B) Model of carbonate precipitation of non-luminescent calcite nodules (dark circles) in the well-drained portion of the season (top) and luminescent calcite nodules (light circles) in the saturated portion of the season (bottom), in a Vertisol at Dance Bayou, Brazoria Co

  2. DRAFT LANDSAT DATA MOSAIC: MONTGOMERY COUNTY, TEXAS; HARRIS COUNTY, TEXAS; FORT BEND COUNTY, TEXAS; BRAZORIA COUNTY, TEXAS; GALVESTON COUNTY, TEXAS

    EPA Science Inventory

    This is a draft Landsat Data Mosaic, which contains remote sensing information for Montgomery County, Texas Harris County, Texas Fort Bend County, Texas Brazoria County, Texas Galveston County, and Texas Imagery dates on the following dates: October 6, 1999 and September 29, 200...

  3. Pleasant Bayou area, Brazoria County, Texas, brine injection experience

    SciTech Connect

    Knutson, C.F.; Bebout, D.G.; Bachman, A.L.

    1981-01-01

    Geothermal brine disposal is one of the facets relating to the geopressured-geothermal energy problem. Subsurface brine disposal is a viable option and a good deal of information is available on brine disposal in the general Gulf Coast area. The specific information presented was developed in a DOE study of salt water disposal experience in Louisiana and Texas (Knutson and Boardman, 1977), an EPA study of large volume brine injection in Brazoria County, Texas (Knutson, 1980) and industrial brine injection experience, especially in Tertiary clastic sediments.

  4. Feldspar diagenesis in the Frio Formation, Brazoria County, Texas Gulf Coast

    SciTech Connect

    Land, L.S.; Milliken, K.L.

    1981-07-01

    Tremendous quantities of detrital feldspar have been dissolved or albitized below about 14000 ft (4267 m) in the Frio Formation (Oligocene), Chocolate Bayou Field, Brazoria County, Texas. Some sandstones no longer contain any unmodified detrital feldspar grains. Material transfer involved in these reactions is immense, affecting at least 15% of the rock volume. Thus, albitization has important implications for several other diagenetic processes that involve feldspars or their components. These processes include formation of secondary porosity, precipitation of quartz and carbonate cements, and the evolution of Na-Ca-Cl formation water.

  5. Records of wells, drillers' logs, water-level measurements, and chemical analyses of ground water in Brazoria, Fort Bend, and Waller counties, Texas, 1985-89

    USGS Publications Warehouse

    Locke, Glenn L.

    1991-01-01

    Data for water wells and ground water in Brazoria, Fort Bend, and Waller Counties were collected during 1985-89 by the U.S. Geological Survey. This report presents a compilation of records for 32 wells in Brazoria County, 19 wells in Fort Bend County, and 16 wells in Waller County. Drillers' logs for 65 wells, water levels for 85 wells, chemical analyses of water for 9 wells, and water levels and chemical analyses of water from previously inventoried wells also are presented in this report.

  6. 77 FR 6620 - Texas Disaster #TX-00385

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... ADMINISTRATION Texas Disaster TX-00385 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 01/30/2012... adversely affected by the disaster: Primary Counties: Harris. Contiguous Counties: Texas: Brazoria,...

  7. Environmental assessment of the brine pipeline replacement for the Strategic Petroleum Reserve Bryan Mound Facility in Brazoria County, Texas

    SciTech Connect

    Not Available

    1993-09-01

    The Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0804, for the proposed replacement of a deteriorated brine disposal pipeline from the Strategic Petroleum Reserve (SPR) Bryan Mound storage facility in Brazoria County, Texas, into the Gulf of Mexico. In addition, the ocean discharge outfall would be moved shoreward by locating the brine diffuser at the end of the pipeline 3.5 miles offshore at a minimum depth of 30 feet. The action would occur in a floodplain and wetlands; therefore, a floodplain/wetlands assessment has been prepared in conjunction with this EA. Based on the analyses in the EA, DOE has determined that the proposed action is not a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 USC. 4321, et seg.). Therefore, the preparation of an Environmental Impact Statement (EIS) is not required, and the Department is issuing this Finding of No Significant Impact (FONSI). This FONSI also includes a Floodplain Statement of Findings in accordance with 10 CFR Part 1022.

  8. 75 FR 45557 - Prevailing Rate Systems; Definition of Tulsa County, OK, and Angelina County, TX, to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... Counties, TX. Santa Clara, CA On March 9, 2009, we published a final rule (74 FR 9951) that abolished the... County, OK, and Angelina County, TX, to Nonappropriated Fund Federal Wage System Wage Areas AGENCY... area of application to the Oklahoma, OK, nonappropriated fund (NAF) Federal Wage System (FWS) wage...

  9. 76 FR 4818 - Drawbridge Operation Regulation; Old Brazos River, Freeport, Brazoria County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... process of cutting the steel truss members off of the swing span, while keeping the span balanced on the... balancing process for the swing span will prevent it from being able to open for emergencies. Per 33 CFR 117... operation of the Union Pacific Railroad Swing Span Bridge across the Old Brazos River, mile 4.4, at...

  10. 76 FR 76298 - Drawbridge Operation Regulation; Old Brazos River, Freeport, Brazoria County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... docket USCG-2011-1053 and are available online by going to http://www.regulations.gov , inserting USCG-2011-1053 in the ``Keyword'' box and then clicking ``Search''. They are also available for...

  11. 76 FR 28060 - Regional Habitat Conservation Plan, Hays County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... of the RHCP and to evaluate alternatives, along with the draft RHCP (74 FR 56655). We included public... Fish and Wildlife Service Regional Habitat Conservation Plan, Hays County, TX AGENCY: Fish and Wildlife... statement, final Hays County regional habitat conservation plan, and draft record of decision. SUMMARY:...

  12. 75 FR 18941 - Environmental Impact Statement: Bexar County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ...), Texas Department of Transportation (TxDOT) and Alamo Regional Mobility Authority (Alamo RMA) issued a... proposed improvements to Loop 1604 in San Antonio, Texas, within Bexar County limits to enhance mobility... Antonio- Bexar County Metropolitan Planning Organization Mobility 2035 Plan (December 2009) and...

  13. Cultural resources survey and assessment of the proposed Department of Energy Freeport to Texas City pipeline, Brazoria and Galveston Counties, Texas. Final report

    SciTech Connect

    Castille, G.J.; Whelan, J.P. Jr.

    1986-01-01

    An intensive survey and testing program of selected segments of a proposed Department of Energy pipeline were conducted by Coastal Environments, Inc., Baton Rouge, Louisiana, during December 1985 and January 1986. The proposed pipeline runs from Texas City, Galveston County to Bryan Mound, Brazoria County. The pedestrian survey was preceded by historical records survey to locate possible historic sites within the DOE righ-of-way. Four prehistoric sites within the ROW (41BO159, 160, 161, 162) and one outside the ROW (41BO163) were located. All are Rangia cuneata middens. The survey results are discussed with particular reference to the environmental settings of the sites and the effectiveness of the survey procedure. Two of the sites located within the ROW were subjected to additional testing. The results of the backhoe testing program are included in the site descriptions, and the scientific value of the sites are presented. 52 refs., 20 figs., 10 tabs.

  14. 75 FR 63533 - Environmental Impact Statement: Cameron County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement: Cameron County, TX AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Rescind Notice of Intent (NOI) to prepare an EIS. SUMMARY: FHWA is...

  15. 75 FR 67806 - Environmental Impact Statement; Nueces County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-03

    ... Federal Highway Administration Environmental Impact Statement; Nueces County, TX AGENCY: Federal Highway... this notice to advise the public that the NOI to prepare an environmental impact statement (EIS) for... were defined as the limits of potential impacts from the proposed action. The study limits were...

  16. Strategic petroleum reserve seaway complex distribution enhancements, Brazoria, Galveston and Harris Counties, Texas. Revised environmental assessment

    SciTech Connect

    Not Available

    1986-02-01

    The Strategic Petroleum Reserve (SPR) of the US Department of Energy (DOE) proposes to construct and operate a 40-inch diameter, 46-mile long buried crude oil pipeline from existing facilities of the SPR Seaway Complex located near Freeport, Texas, to an existing commercial crude oil terminal near Texas City, Texas. In May 1984, DOE issued an Environmental Assessment ((EA); DOE/EA-0252) and a Finding of No Significant Impact for this action. The May 1985 EA addressed the construction and operation of a DOE-owned buried crude oil pipeline from Bryan Mound to the ARCO Terminal located in Texas City, Galveston County, Texas. The EA assessed three alternative alignments for outing the pipeline from Bryan Mound past Freeport to a common point near Stratton Ridge. From Stratton Ridge to Texas City, one route segment was considered. All three alternative alignments around Freeport were subsequently determined to be unsuitable for safe construction of a large-diameter buried pipeline, primarily because of crowded pipeline corridors and restricted pipeline rights-of-way (ROW). Therefore, the SPR identified and is herein considering a fourth alternative route segment from Bryan Mound through the City of Freeport, across the Old Brazos River and Dow Barge Canal, and northward to Stratton Ridge. The route is about 11 miles long, and is in or adjacent to existing utility and pipeline right-of-way for about 70% of its length. Crude oil throughput capacity for all cases is 1.10 million barrels per day. This revised EA addresses environmental impacts of construction and operation of the pipeline along the fourth subalternative route segment, as compared to impacts from the three previously considered alternative route segments. 11 refs., 3 figs., 1 tab.

  17. 75 FR 31463 - Comal County Regional Habitat Conservation Plan, Comal County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... Federal Register on October 16, 2008 (73 FR 61433). A public scoping meeting was held on December 4, 2008... Fish and Wildlife Service Comal County Regional Habitat Conservation Plan, Comal County, TX AGENCY... statement, draft habitat conservation plan, and permit application; announcement of a public...

  18. 77 FR 40406 - Cancellation of Supplemental Environmental Impact Statement (SEIS); Travis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... County, TX AGENCY: Federal Highway Administration, DOT. ACTION: Cancellation of Notice of Intent to... (TxDOT) are issuing this notice to advise the public that the Notice of Intent (NOI) to prepare a.... SUPPLEMENTARY INFORMATION: On August 15, 2008, TxDOT, in cooperation with the FHWA, announced its intent...

  19. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  20. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  1. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  2. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX... REGULATIONS EXEMPTIONS, COMMERCIAL ZONES, AND TERMINAL AREAS Commercial Zones § 372.237 Cameron, Hidalgo, Starr, and Willacy Counties, TX. (a) Transportation within a zone comprised of Cameron, Hidalgo,...

  3. Hydrologic, water-quality, and sediment-quality data for the Christmas Bay system, Brazoria County, Texas, February 1999-March 2000

    USGS Publications Warehouse

    East, Jeffery W.

    2002-01-01

    The Christmas Bay system is a group of three small secondary bays (Christmas, Bastrop, and Drum Bays) at the southwestern end of the Galveston Bay estuarine system in Brazoria County, Texas. During February 1999-March 2000, hydrologic, water-quality, and sediment-quality data were collected from each of the three bays to establish baseline conditions. Gage-height fluctuations closely matched open-water tidal fluctuations. Rainfall during February 1999-February 2000 was about 20 percent below the annual average. Specific conductance, pH, water temperature, and dissolved oxygen monitored at 30-minute intervals in Christmas Bay for 13 months showed seasonal variations typical of monitoring stations on the Texas Gulf Coast. Prevailing winds were from the southeast. Monthly water-quality sampling for 13 months showed that in each of the three bays concentrations of major ions were small, and most nutrient concentrations were at or less than minimum reporting levels; indicator bacteria counts were consistently higher in samples collected from Drum Bay. Several trace elements (sampled twice) were detected in small concentrations. The only organochlorine pesticides (sampled once) that were greater than minimum reporting levels were atrazine, deethylatrazine, metolachlor, and simazine. During February 29-March 29, 2000, three semipermeable membrane devices were deployed at the Christmas Bay monitoring station. Seven of 77 semivolatile organic compounds analyzed in the lipids from the devices were detected in minute amounts. Analyses of surficial bed sediment sampled once in each of the three bays yielded detections of a number of semivolatile organic compounds; all concentrations were less than 10 micrograms per liter and much less than the respective benchmark concentration for those compounds that have had a benchmark concentration established for the protection of aquatic life.

  4. 78 FR 1935 - Union Pacific Railroad Company-Abandonment and Discontinuance Exemption-in Cameron County, TX...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-09

    ... Cameron County, TX; Brownsville and Matamoras Bridge Company--Abandonment Exemption--in Cameron County, TX... distance of 7.98 miles in Cameron County, Tex. (collectively, the Line). The Line traverses United States...'s Brownsville Subdivision will be transferred to Cameron County, Tex., and/or the City...

  5. 75 FR 70945 - Caddo National Wildlife Refuge, Harrison County, TX; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    .... Ecoregional Issues Potential impacts of climate change Habitat Issues Bottomland Hardwood habitat maintenance... County, TX, and encompasses approximately 7,500 acres of Piney Woods, mature Baldcyprus Forests, and... bayous twist through forests teeming with a great diversity of aquatic and terrestrial plant...

  6. 49 CFR 372.237 - Cameron, Hidalgo, Starr, and Willacy Counties, TX.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Cameron, Hidalgo, Starr, and Willacy Counties, TX. 372.237 Section 372.237 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS EXEMPTIONS, COMMERCIAL ZONES,...

  7. 76 FR 61135 - Environmental Impact Statement: El Paso County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ...FHWA is issuing this notice to advise the public that the NOI to prepare an environmental impact statement (EIS) for proposed improvements to Loop 375 Border Highway West, in El Paso County, Texas, is being...

  8. Simulation-optimization approach to assess groundwater availability in Refugio County, TX

    NASA Astrophysics Data System (ADS)

    Uddameri, V.; Kuchanur, M.

    2007-01-01

    Sustainable management of groundwater resources is critical for viable development of semi-arid regions. Refugio County, TX, is predominantly a rural community that is in close proximity to two large urban areas of Corpus Christi and San Antonio. Large-scale water supply projects are being planned to export surplus water available in Refugio County to nearby growing cities. Being a coastal county with several sensitive bays and estuaries, these projects have caused concerns with regard to decreases in freshwater inflows to coastal bodies and raised the possibility of saltwater intrusion. A simulation model characterizing groundwater flow in the shallower unconfined and the deeper semi-confined formations of the Gulf coast aquifer was calibrated and evaluated. The model results were used in conjunction with a mathematical programming scheme to estimate maximum available groundwater in the county. Stakeholder concerns were incorporated as constraints, which included prevention of saltwater intrusion in the aquifer, limiting the amount of allowable drawdown in shallow aquifers, as well as maintaining current flow gradients especially near baseflow-dependent streams and rivers. For the conditions assumed in this study, the model results indicate that roughly 4.93 × 107 m3 of water can be extracted in a typical year. The management model was noted to be very sensitive to the imposed saltwater intrusion constraint.

  9. Groundwater withdrawals 1976, 1990, and 2000--10 and land-surface-elevation changes 2000--10 in Harris, Galveston, Fort Bend, Montgomery, and Brazoria Counties, Texas

    USGS Publications Warehouse

    Kasmarek, Mark C.; Johnson, Michaela R.

    2013-01-01

    Measured land-surface-elevation changes from December 31, 2000, to December 31, 2010, ranged from an elevation increase of 0.06 feet (ft), or an average increase in elevation of 0.006 ft per year, at the Seabrook borehole extensometer located near Seabrook, Tex., to an elevation decrease of 1.28 ft, or an average decrease in elevation of 0.128 ft per year, at a PAM station north of Jersey Village, Tex. (PAM 07). Measured land-surface-elevation changes from December 31, 2005, to December 31, 2010, ranged from an elevation increase of 0.07 ft, or an average increase in elevation of 0.014 ft per year, at PAM 09 in far northeastern Harris County to an elevation decrease of 0.51 ft, or an average decrease in elevation of 0.102 ft per year, at PAM 07.

  10. 76 FR 9640 - Prevailing Rate Systems: Santa Clara, CA, Tulsa County, OK, and Angelina County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... INFORMATION: On August 3, 2010, the U.S. Office of Personnel Management (OPM) issued a proposed rule (75 FR..., ``Santa Clara,'' which was abolished as a NAF FWS wage area by a final rule (74 FR 9951) published on... MANAGEMENT 5 CFR Part 532 RIN 3206-AM22 Prevailing Rate Systems: Santa Clara, CA, Tulsa County, OK,...

  11. The relationship between seismicity and wastewater injection in Johnson County, TX

    NASA Astrophysics Data System (ADS)

    Lee, S. S.; Walter, J. I.; Frohlich, C.; DeShon, H. R.

    2015-12-01

    In light of recent research that suggests some high-rate wastewater injection wells from commercial oil and gas operations are casually linked to recent earthquakes in North Texas and Oklahoma, we apply a waveform cross-correlation technique to continuous waveform data from 38 seismic stations across Texas and Oklahoma using templates from 96 cataloged events from 2010-2015. We focus on an area near Venus TX, 40 km south of the Dallas-Fort Worth metropolitan area in Johnson County where a M4.0 earthquake was reported by the USGS on 7 May 2015. The epicenter was within several km of 4 high rate wells with max injection rates ranging between 684,000-833,000 barrels/month. Templates were chosen from the USGS and locally derived Venus aftershock sequence, events in the ANSS catalog with a minimum magnitude of 2 between 2009-2015, and previously located earthquakes recorded by USArray stations between 2009-2011. In Johnson County, there are 27 wastewater injection wells, each with a reported maximum injection rate of 104,000 barrels/month and greater. We detected 494 events within Johnson and adjacent counties, with approximately 36% of the detections occurring within 10 km of the Venus earthquake, spanning March 2010 to June 2015. Most of the seismicity occurs adjacent to higher rate injection wells, suggesting a link between monthly injection rate and earthquake occurrence. Template matching allows us to detect earthquakes otherwise too small to be picked up by routine earthquake identification methods and informs our research concerning the presence and spatial distribution of possibly induced, small magnitude earthquakes. We plan to apply this technique to detect seismicity that may have occurred prior to the start of wastewater injection or felt earthquakes.

  12. 75 FR 8994 - Certification of the Attorney General; Williamson County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... necessary to enforce the guarantees of the Fourteenth and Fifteenth Amendments of the Constitution of the United States in Williamson County, Texas. This county is included within the scope of the determinations...). Dated: February 23, 2010. Eric H. Holder Jr., Attorney General of the......

  13. 76 FR 16294 - Drawbridge Operation Regulation; Buffalo Bayou, Mile 4.3, Houston, Harris County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-23

    ..., Houston, Harris County, Texas. The bridge was replaced with a fixed bridge in 1991 and the operating...-mail Mr. Jim Wetherington, Bridge Specialist, Coast Guard; telephone 504-671-2128, e-mail james.r... CFR 117.955(b), was removed and replaced with a fixed span bridge in 1991. The bridge operator...

  14. 75 FR 74073 - Laguna Atascosa National Wildlife Refuge, Cameron and Willacy Counties, TX; Final Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... Register July 19, 2004 (69 FR 43010). Laguna Atascosa NWR is located in Cameron and Willacy Counties, Texas...; Final Comprehensive Conservation Plan and Finding of No Significant Impact for Environmental Assessment... and Wildlife Service (Service), announce the availability of our final comprehensive conservation...

  15. 75 FR 54420 - Cancellation of Supplemental Environmental Impact Statement (SEIS); Travis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ... Statement (SEIS) would be prepared for the proposed SH 71 roadway between Riverside Drive and SH 130 in... for proposed improvements to State Highway (SH) 71 from Riverside Drive to SH 130, in Travis County... to 40 CFR 1508.22 and 43 TAC Sec. 2.5(e)(2) for proposed improvement of SH 71 from Riverside Drive...

  16. Comparative palynology of clastics and lignites from the Manning Formation, Jackson Group, Upper Eocene, Grimes County, TX

    SciTech Connect

    Gennett, J.A.

    1996-09-01

    The 3500 lignite seam at the Gibbons Creek Mine in Grimes County, TX was sampled for pollen and spores at 10 cm intervals. The majority of samples are dominated (to 60%) by Momipites from the Juglandaceae (walnut family), as is typical of Jackson Group sediments. Other palynomorph taxa vary systematically, with a peak of pollen of the freshwater tree Nyssa (blackgum) and associated Rboipites angustus (to 17%) occurring at the base. Higher in the seam, increase (to 55%) of Cupuliferoipollenites (a chestnut-like grain) and Cyrillaceae-pollenites? ventosus (to 7%) percentages may indicate a higher salinity environment. A Chrysophyllum (satin leaf) peak (to 25%) near the top of the seam suggests relatively shallow fresh-water conditions. Core samples from an interval above the lignites represent a transgressive-regressive cycle in inner shelf clastics. These samples were taken at 40 cm or greater intervals and reveal the regional pollen flora. Although minor changes occur, palynomorph spectra are for the most part homogenous. The dominant grain is again Momipites coryloides, but in general percentages are lower (to 35%). Cupuliferoipollenites (to 17%), Chrysophyllum (to 5%), and Rhoipites angustus (to 3%) are not less important, but do not peak as they do in the lignite spectra. Palm leaf megafossils; in one sample suggest a clastic wetland; in this sample palm pollen (mostly Arecipites, representing the modern saw palmetto) reaches 73%. Another sample contains high (26%) percentages of the fern spore Lygodiumsporites adriennis. High percentages of these two taxa do not occur in the lignite samples.

  17. 77 FR 19521 - Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-02

    ... (OPM) issued a proposed rule (76 FR 70365) to redefine Burleson and Lampasas Counties, TX, from the... 3206-AM50 Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund... of the Austin, TX, and Waco, TX, appropriated fund Federal Wage System (FWS) wage areas. The...

  18. Upper Strawn (Desmoinesian) carbonate and clastic depositional environments, SE King County, TX

    SciTech Connect

    Boring, T.H. )

    1990-05-01

    The Pennsylvanian upper Strawn Group of southeast King County, Texas, provides a unique setting to study interactions between coeval carbonate and clastic deposition during the Desmoinesian. One of the most perplexing problems is the relationship of massive Pennsylvanian platform carbonates to shallow-water marine and deltaic sediments. Within the study area carbonate facies were deposited along the northern edge of the Knox-Baylor trough on the Spur platform, and terrigenous clastics were carried toward the Midland basin through the Knox-Baylor trough. Based on the analysis of subsurface cores, five carbonate lithofacies and four clastic lithofacies were recognized in southeast King County, Texas. The distribution and geometry of these lithofacies are related to variations in the rate of subsidence in the Knox-Baylor trough, Pennsylvanian tectonics, deltaic progradation, avulsion and compaction. The platform carbonates within the northern region record environments within the carbonate platform complex, including middle platform, outer platform, algal mound, and platform margin. The quartzarenitic sandstones within the southern region occur in a variety of complex depositional geometries, including distributary bar fingers, lobate deltas, and offshore bars. The upper Strawn Group provides an attractive area for exploration geology. Both carbonates and clastics provide excellent reservoirs from a depth of approximately 5,000 to 6,000 ft. Total production since the early 1940s, within the area is over 100,000,000 bbl of oil. Multiple pay zones within a 600-ft interval also provide an added incentive for exploration. Areas within and around the Knox-Baylor trough deserve additional study due to these relatively shallow, unexplored, multiple pay zones.

  19. 76 FR 70365 - Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... Austin, TX and Waco, TX, Appropriated Fund Federal Wage System Wage Areas AGENCY: U.S. Office of... Management is issuing a proposed rule that would redefine the geographic boundaries of the Austin, TX, and... Burleson and Lampasas Counties, TX, from the Austin wage area to the Waco wage area. These changes...

  20. Brazoria County Re-Leveling Pleasant Bayou Geopressured Well Site

    SciTech Connect

    1984-07-01

    The purpose is to conduct first order leveling surveys as part of an ongoing environmental monitoring program for geopressured-geothermal test wells. The scope is to Conduct First Order, Class I, leveling to monitor subsidence of previously installed and leveled bench marks, established by the National Geodetic Survey (NGS) and Vernon F. Meyer and Associates, Inc., in the area of the Pleasant Bayou geopressured test well. All leveling surveys to conform to NGS standards and specifications.

  1. Public health assessment for Longhorn Army Ammunition Plant, Karnack, Harrison County, Texas, Region 6, CERCLIS number TX6213820529. Final report

    SciTech Connect

    1999-07-09

    Longhorn Army Ammunition Plant (Longhorn) is an 8,493 acre government-owned former industrial facility approximately 14 miles northeast of Marshall, Harrison County, Texas. Longhorn has been intermittently in operation since 1942 when it was established to produce the explosive 2,4,6-trinitrotoluene (TNT). Pyrotechnic ammunition also was produced at Longhorn and Morton Thiokol Corporation produced a plastic explosive at the facility until August 1997. According to document record for the hazardous ranking system, releases of 1,3-dinitrobenzene, 1,3,5-trinitrobenzene, arsenic, barium, chromium, and lead occurred. The Agency for Toxic Substances and Disease Registry (ATSDR) reviewed available environmental information for the site and evaluated several potential exposure situations. These exposure situations include potential contact with site contaminants in surface water, sediment, surface soil, wasteline material, and groundwater. Although site-related contaminants have been found in these various environmental media, currently the contaminants are not accessible, on or off the site, at levels that would pose a public health threat. Based on available information, the authors have concluded that overall, the Longhorne Army Ammunition Plant poses on apparent public health hazard. In the future, the conclusion category for this site could change if additional data were to indicate that contaminants from the site were migrating towards the public water supply wells near the site.

  2. 77 FR 24756 - Texas Disaster #TX-00387

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... ADMINISTRATION Texas Disaster TX-00387 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 04/17/2012... adversely affected by the disaster: Primary Counties: Dallas, Kaufman, Tarrant. Contiguous Counties:...

  3. 78 FR 33464 - Texas Disaster #TX-00405

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ... ADMINISTRATION Texas Disaster TX-00405 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 05/29/2013... adversely affected by the disaster: Primary Counties: Ellis, Hood, Johnson. Contiguous Counties:...

  4. 75 FR 62437 - Texas Disaster #TX-00364

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ... ADMINISTRATION Texas Disaster TX-00364 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 09/29/2010... determined to be adversely affected by the disaster: Primary Counties: Nueces, Contiguous Counties:...

  5. 76 FR 28841 - Texas Disaster # TX-00376

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... ADMINISTRATION Disaster Declaration 12564 and 12565 Texas Disaster TX-00376 AGENCY: U.S. Small Business... State of Texas dated 05/09/2011. Incident: Wichita County Complex Wildfires. Incident Period: 04/15/2011.... Contiguous Counties: Texas: Archer, Baylor, Clay, Wilbarger, Oklahoma: Cotton, Tillman. The Interest...

  6. 75 FR 1421 - Texas Disaster # TX-00354

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-11

    ... ADMINISTRATION Texas Disaster TX-00354 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 01/04/2010... the disaster: Primary Counties: Angelina. Contiguous Counties: Texas: Cherokee, Houston,...

  7. 76 FR 40765 - Texas Disaster #TX-00378

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... ADMINISTRATION Texas Disaster TX-00378 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 07/05/2011... adversely affected by the disaster: Primary Counties: Grimes. Contiguous Counties: Texas: Brazos,...

  8. 76 FR 24555 - Texas Disaster #TX-00375

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... ADMINISTRATION Texas Disaster TX-00375 AGENCY: Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas. Dated 04/26/2011. Incident... adversely affected by the disaster: Primary Counties: Jeff Davis. Contiguous Counties: Texas,...

  9. 78 FR 27468 - Texas Disaster # TX-00401

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... ADMINISTRATION Texas Disaster TX-00401 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated May 2, 2013... adversely affected by the disaster: Primary Counties: Mclennan. Contiguous Counties: Texas: Bell;...

  10. 78 FR 72140 - Texas Disaster # TX-00417

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-02

    ... ADMINISTRATION Texas Disaster TX-00417 AGENCY: U.S. Small Business Administration ACTION: Notice SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 11/22/2013... adversely affected by the disaster: Primary Counties: Caldwell, Hays, Travis. Contiguous Counties:...

  11. Shallow groundwater monitoring at the SACROC oilfield, Scurry County, TX: good news for geologic storage of CO2 despite a complex hydrogeologic and geochemical setting (Invited)

    NASA Astrophysics Data System (ADS)

    Smyth, R. C.; Romanak, K.; Yang, C.; Hovorka, S.

    2009-12-01

    The SACROC water study is the first comprehensive research project with application to geologic storage (GS) of CO2 that focuses on collection and interpretation of field measurements of groundwater (water level and water chemistry data). CO2 has been injected for enhanced oil recovery at the SACROC oilfield in Scurry County, TX since 1972. Hence, we have a perfect natural laboratory and an analog for monitoring future commercial CO2 sequestration sites. Kinder Morgan currently operates the SACROC oilfield where over 150 million metric tons (MMT) of CO2 has been injected for EOR at ~2 km depth; over 75 MMT of the CO2 has been produced and re-injected. CO2 is assumed to be trapped in the deep subsurface at SACROC. The goals of monitoring shallow groundwater over CO2 injection sites are to (1) confirm that CO2 has remained in the deep subsurface and (2) assess impacts to water quality if CO2 were to migrate upward along conduit flow paths (e.g. leaking well bores). We collected groundwater and stratigraphic data within an ~3,000 km2 area centered on SACROC to establish regional variability prior to assessing potential impacts to groundwater from CO2 injection. Groundwater data include results from five sampling trips between June 2006 and November 2008, and a compilation of historical data from the Texas Water Development Board database, dating back to 1936. Sources of complexity that contribute to data interpretation challenges include: (1) regional historic oilfield activity, (2) multiple freshwater-bearing strata in the regional Dockum aquifer, (3) sampled wells screened in shallowest (30 m), deepest (150 m), or across both water-bearing zones, (4) variable discharge rate of sampled wells (<5 to >250 gpm), (5) groundwater flow divide that bisects SACROC, (6) variable aquifer recharge mechanisms, (7) temporal variability in groundwater levels and chemistry, (8) cation exchange, (9) presence of biogenically-produced CO2 in aquifer, and (10) incongruent dissolution

  12. 75 FR 52016 - Notice of Inventory Completion: Texas Parks and Wildlife Department, Austin, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ... National Park Service Notice of Inventory Completion: Texas Parks and Wildlife Department, Austin, TX... Department, Austin, TX. The human remains and associated funerary objects were removed from El Paso County... Road, Austin, TX 78744, telephone (512) 389-4876, before September 23, 2010. Repatriation of the...

  13. 75 FR 48384 - Texas Disaster #TX-00361

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... ADMINISTRATION Texas Disaster TX-00361 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of Texas (FEMA-1931-DR... Counties (Economic Injury Loans Only): Texas: Brooks, Crockett, Dimmit Duval, Edwards, Kenedy, Kinney...

  14. Superfund Record of Decision (EPA Region 6): Petro-Chemical (Turtle Bayou), Liberty County, TX. (Second remedial action), September 1991. Final report

    SciTech Connect

    Not Available

    1991-09-06

    The 500-acre Petro-Chemical (Turtle Bayou) site is in Liberty County, Texas. Current land use in the area is divided among cropland, pasture, range, forest, and small rural communities. Since 1971, numerous undocumented disposal activities occurred onsite involving primarily petrochemical wastes. The ROD for OU2 focuses on three areas of contamination at the site affecting soil and ground water contamination, known as the main waste area, the east disposal area, and the Bayou disposal area. The primary contaminants of concern affecting the soil and ground water are VOCs including benzene and xylenes; other organics including PAHs; and metals including lead. The selected remedial action for the site includes treating 302,800 cubic yards of contaminated soil onsite using in-situ vapor extraction to remove VOCs, controlling vertical air infiltration using an engineered soil and synthetic liner cap; consolidating lead-contaminated soil in the Main Waste Area, followed by capping.

  15. Geothermal energy impact in Brazoria County. Final report, 15 July 1978-November 30, 1979

    SciTech Connect

    Horine, B.

    1980-06-01

    All activities performed by Alvin Community College and the University of Texas at Austin in association with the development of Geopressured-Geothermal energy are contained in this report. A discussion of the progress of the Test Well is also contained herein. Public seminars and workshops were presented to the local community. A summer institute in energy was also presented to local public school teachers. A compaign to publicize the development of the new energy resource was also waged. An overall evaluation of the project is also attached.

  16. Environmental assessment: Strategic Petroleum Reserve Seaway Complex distribution enhancements, Brazoria, Galveston, and Harris Counties, Texas

    SciTech Connect

    Not Available

    1984-12-01

    The Strategic Petroleum Reserve (SPR) of the US Department of Energy proposes to construct and operate a 42-inch buried crude oil pipeline, between 48 and 53 miles long, to transport crude oil from existing facilities of the SPR Seaway Complex located near Freeport, Texas, to an existing commercial crude oil terminal near Texas City, Texas. Three subalternative pipeline segments are under consideration for the origin of the route at the SPR Bryan Mound storage site located near Freeport, Texas. Crude oil throughput for all cases is 1,315,000 bpd. The environmental impacts of the proposed action are related to pipeline construction and operation. Potential impacts from pipeline construction are primarily concerned with prime farmland and wetlands. The use of ''double ditching'' techniques to restore original soil profile will minimize impacts to prime farmlands, and impacts on wetlands. Compliance with US Army Corps of Engineers permit conditions (which specify restoration of land to original contours, disposal of spoil in upland areas, and revegetation of riparian areas) will mitigate impacts on wetlands. Water use during pipeline testing in accordance with permit conditions is not expected to be significant. Potential impacts from pipeline operation are primarily concerned with accidental releases of crude oil to the environment. As a worst-case, 0.01 spill events would occur during one six-month drawdown, and the volume of oil spilled would be about 18,000 bbl for the pipeline. Because the pipeline will be buried, the occurrence of a major pipeline break releasing large quantities of crude oil is unlikely. Testing and inspection of buried pipeline, and the development of an oil spill contingency plan will reduce the seriousness of an oil spill. Impacts on floodplains are also expected to be minor. 20 refs., 4 figs., 2 tabs.

  17. Pleasant Bayou geopressured/geothermal testing project, Brazoria County, Texas. Final report

    SciTech Connect

    Ortego, P.K.

    1985-07-01

    Phase II-B production testing of the Pleasant Bayou No. 2 well began September 22, 1982. The test plan was designed to evaluate the capabilities of the geopressured-geothermal reservoir during an extended flow period. Tests were conducted to determine reservoir areal extent; aquifer fluid properties; fluid property change with production; information on reservoir production drive mechanism; long-term scale and corrosion control methods; and disposal well operations. Operatinal aspects of geopressured-geothermal production were also evaluated. The test was discontinued prematurely in May 1983 because of a production tubing failure. Most of the production tubing was recovered from the well and cause of the failure was determined. Plans for recompletion of the well were prepared. However, the well was not recompleted because of funding constraints and/or program rescheduling. In March 1984, the Department of Energy, Nevada Operations Office (DOE/NV) directed that the site be placed in a standby-secured condition. In August 1984, the site was secured. Routine site maintenance and security was provided during the secured period.

  18. 76 FR 9639 - Prevailing Rate Systems; Redefinition of the Shreveport, LA; Texarkana, TX; Milwaukee, WI; and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    .... Office of Personnel Management (OPM) issued a proposed rule (75 FR 58339) to redefine Upshur County, TX... Forest Jackson Juneau Langlade Lincoln Marathon Marinette Menominee Oneida Pepin Portage Price...

  19. Impact of Large-scale Circulation Patterns on Surface Ozone Variability in Houston-Galveston-Brazoria

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Jia, B.; Xie, Y.

    2015-12-01

    The Bermuda High (BH) is a key driver of large-scale circulation patterns for Southeastern Texas and other Gulf coast states in summer, with the expected influence on surface ozone through its modulation of marine air inflow with lower ozone background from the Gulf of Mexico. We develop a statistical relationship through multiple linear regression (MLR) to quantify the impact of the BH variations on surface ozone variability during the ozone season in the Houston-Galveston-Brazoria (HGB) area, a major ozone nonattainment region on the Gulf Coast. We find that the variability in BH location, represented by a longitude index of the BH west edge (BH-Lon) in the MLR, explains 50-60% of the year-to-year variability in monthly mean ozone over HGB for Jun and July during 1998-2013, and the corresponding figure for Aug and Sep is 20%. Additional 30%-40% of the ozone variability for Aug and Sep can be explained by the variability in BH strength, represented by two BH intensity indices (BHI) in the MLR, but its contribution is only 5% for June and not significant for July. Including a maximum Through stepwise regression based on Akaike Information Criterion (AIC), the MLR model captures 58~72% of monthly ozone variability during Jun-Sep with a cross-validation R2 of 0.5. This observation-derived statistical relationship will be valuable to constrain model simulations of ozone variability attributable to large-scale circulation patterns.

  20. 60-day waste compatibility safety issue and final results for 244-TX DCRT, grab samples TX-95-1, TX-95-2, and TX-95-3

    SciTech Connect

    Esch, R.A.

    1996-01-01

    Three grab samples (TX-95-1, TX-95-2, and TX-95-3) were taken from tank 241- TX-244 riser 8 on November 7, 1995 and received by the 222-S Laboratory on that same day. Samples TX-95-1 and TX-95-2 were designated as supernate liquids, and sample TX-95-3 was designated as a supernate/sludge. These samples were analyzed to support the waste compatibility safety program. Accuracy and precision criteria were met for all analyses. No notifications were required based on sample results. This document provides the analysis to support the waste compatibility safety program.

  1. 33 CFR 80.840 - Sabine Pass, TX to Galveston, TX.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sabine Pass, TX to Galveston, TX... INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Eighth District § 80.840 Sabine Pass, TX to Galveston, TX. (a) A line drawn from the Sabine Pass East Jetty Light to the seaward end of the Sabine Pass...

  2. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Brazos River, TX to the Rio Grande, TX. 80.850 Section 80.850 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... to the Rio Grande, TX. (a) Except as otherwise described in this section lines drawn continuing...

  3. 33 CFR 80.850 - Brazos River, TX to the Rio Grande, TX.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Brazos River, TX to the Rio Grande, TX. 80.850 Section 80.850 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... to the Rio Grande, TX. (a) Except as otherwise described in this section lines drawn continuing...

  4. 76 FR 53019 - Texas Disaster #TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... ADMINISTRATION Texas Disaster TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Notice SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance Only for the..., Fort Worth, TX 76155. FOR FURTHER INFORMATION CONTACT: A Escobar, Office of Disaster Assistance,...

  5. TX-100 manufacturing final project report.

    SciTech Connect

    Ashwill, Thomas D.; Berry, Derek S.

    2007-11-01

    This report details the work completed under the TX-100 blade manufacturing portion of the Carbon-Hybrid Blade Developments: Standard and Twist-Coupled Prototype project. The TX-100 blade is a 9 meter prototype blade designed with bend-twist coupling to augment the mitigation of peak loads during normal turbine operation. This structural coupling was achieved by locating off axis carbon fiber in the outboard portion of the blade skins. The report will present the tooling selection, blade production, blade instrumentation, blade shipping and adapter plate design and fabrication. The baseline blade used for this project was the ERS-100 (Revision D) wind turbine blade. The molds used for the production of the TX-100 were originally built for the production of the CX-100 blade. The same high pressure and low pressure skin molds were used to manufacture the TX-100 skins. In order to compensate for the difference in skin thickness between the CX-100 and the TX-100, however, a new TX-100 shear web plug and mold were required. Both the blade assembly fixture and the root stud insertion fixture used for the CX-100 blades could be utilized for the TX-100 blades. A production run of seven TX-100 prototype blades was undertaken at TPI Composites during the month of October, 2004. Of those seven blades, four were instrumented with strain gauges before final assembly. After production at the TPI Composites facility in Rhode Island, the blades were shipped to various test sites: two blades to the National Wind Technology Center at the National Renewable Energy Laboratory in Boulder, Colorado, two blades to Sandia National Laboratory in Albuquerque, New Mexico and three blades to the United States Department of Agriculture turbine field test facility in Bushland, Texas. An adapter plate was designed to allow the TX-100 blades to be installed on existing Micon 65/13M turbines at the USDA site. The conclusion of this program is the kick-off of the TX-100 blade testing at the three

  6. 77 FR 61471 - Environmental Impact Statement: Travis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-09

    ... 290 at Circle Drive and along SH 71 at Silvermine Drive. The project is listed in the Capital Area... lanes. In addition, environmental stewardship and sustainability strategies will be developed to address... social equity, economic development, and a satisfying quality of life, plus local goals consistent...

  7. 76 FR 36613 - Environmental Impact Statement; Nueces County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... is listed in the Corpus Christi Metropolitan Planning Organization's Metropolitan Transportation Plan... on input from Federal, state, and local agencies, as well as private organizations and concerned... appropriate Federal, state, and local agencies, and to private organizations and citizens who have...

  8. 76 FR 52563 - Special Local Regulations; Sabine River, Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ...) entitled Special Local Regulations; Sabine River, Orange, TX in the Federal Register (76 FR 103). We... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Sabine River, Orange, TX... Events; Sabine River, Orange, TX. (a) Definitions. As used in this section ``Participant Vessel''...

  9. 76 FR 65775 - Environmental Impact Statement: Harris County, Texas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... Federal Highway Administration Environmental Impact Statement: Harris County, Texas AGENCY: Federal... and 43 TAC Sec. 2.5(e)(2), the FHWA and the Texas Department of Transportation (TxDOT) are issuing... proposed North Houston Highway Improvement Project, in Harris County, Texas. The proposed project and...

  10. 78 FR 36631 - Texas Disaster #TX-00408

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00408 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This... Deadline Date: 03/12/2014. ADDRESSES: Submit completed loan applications to: U.S. Small...

  11. 78 FR 48764 - Texas Disaster # TX-00413

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00413 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This... applications to: U.S. Small Business Administration, Processing and Disbursement Center, 14925 Kingsport...

  12. 76 FR 35260 - Texas Disaster # TX-00375

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ... ADMINISTRATION Texas Disaster TX-00375 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Administrative declaration of a disaster for the State of TEXAS dated 04/26... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409...

  13. 78 FR 39822 - Texas Disaster #TX-00409

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... ADMINISTRATION Texas Disaster TX-00409 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 06/25/2013... CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409 3rd Street...

  14. 75 FR 70763 - Texas Disaster #TX-00363

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-18

    ... ADMINISTRATION Texas Disaster TX-00363 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 11/09/2010... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409...

  15. 76 FR 60959 - Texas Disaster # TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-30

    ... ADMINISTRATION Texas Disaster TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for Public Assistance Only for the... 76155. FOR FURTHER INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small...

  16. 75 FR 48384 - Texas Disaster #TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Texas Disaster TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This... State of TEXAS (FEMA-1931- DR), dated 08/03/2010. Incident: Hurricane Alex. Incident Period:...

  17. 76 FR 15358 - Texas Disaster #TX-00371

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... ADMINISTRATION Texas Disaster TX-00371 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Texas dated 03/14/2011. Incident: Texas Panhandle Wildfires. Incident Period: 02/27/2011 through 02/28/2011. Effective Date:...

  18. 76 FR 58329 - Texas Disaster #TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... ADMINISTRATION [Disaster Declaration 12815 and 12816 Texas Disaster TX-00381 AGENCY: U.S. Small Business... the State of Texas (FEMA-4029-DR), dated 09/09/2011. Incident: Wildfires. Incident Period: 08/30/2011... Loans Only): Texas: Caldwell, Fayette, Lee, Travis, Williamson. The Interest Rates are: ] Percent...

  19. Big Bend National Park, TX, USA, Mexico

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The Sierra del Carmen of Mexico, across the Rio Grande River from Big Bend National Park, TX, (28.5N, 104.0W) is centered in this photo. The Rio Grande River bisects the scene; Mexico to the east, USA to the west. The thousand ft. Boquillas limestone cliff on the Mexican side of the river changes colors from white to pink to lavender at sunset. This severely eroded sedimentary landscape was once an ancient seabed later overlaid with volcanic activity.

  20. 78 FR 37793 - In the Matter of: Jose Arturo Ramon-Herrada, Inmate Number #90903-279, CI Willacy County...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... most recent being that of August 15, 2012 (77 FR 49699 (August 16, 2012)), has continued the... Willacy County, Correctional Institution, 1800 Industrial Drive, Raymonville, TX 78580 Order Denying... Institution, 1800 Industrial Drive, Raymonville, TX 78580, and when acting for or on behalf of...

  1. Final report for the geothermal well site restoration and plug and abandonment of wells: DOE Pleasant Bayou test site, Brazoria County, Texas

    SciTech Connect

    Rinehart, Ben N.; Seigel, Ben H.

    1994-03-13

    For a variety of reasons, thousands of oil and gas wells have been abandoned in the Gulf Coast Region of the United States. Many of these wells penetrated geopressured zones whose resource potential for power generation was undervalued or ignored. The U.S. Department of Energy (DOE) Geopressured-Geothermal Research Program was chartered to improve geothermal technology to the point where electricity could be commercially produced from a substantial number of geopressured resource sites. This research program focused on relatively narrow technical issues that are unique to geopressured resources such as the ability to predict reservoir production capacity based on preliminary flow tests. Three well sites were selected for the research program. These are the Willis Hulin and Gladys McCall sites in Louisiana, and the Pleasant Bayou site in Texas. The final phase of this research project consists of plug and abandonment (P&A) of the wells and site restoration.

  2. Hanford Single Shell Tank Leak Causes and Locations - 241-TX Farm

    SciTech Connect

    Girardot, C. L.; Harlow, D> G.

    2014-07-22

    This document identifies 241-TX Tank Farm (TX Farm) leak causes and locations for the 100 series leaking tanks (241-TX-107 and 241-TX-114) identified in RPP-RPT-50870, Rev. 0, Hanford 241-TX Farm Leak Inventory Assessment Report. This document satisfies the TX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  3. 78 FR 67296 - Establishment of Class D Airspace; Mesquite, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... Meacham Blvd., Fort Worth, TX 76137; telephone 817-321- 7716. SUPPLEMENTARY INFORMATION: History On August... establish Class D airspace for Mesquite Metro Airport, Mesquite, TX (78 FR 48842) Docket No. FAA-2012- 0580...) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February...

  4. 78 FR 48298 - Amendment of Class E Airspace; Commerce, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Commerce, TX AGENCY: Federal... Commerce, TX, area, creating additional controlled airspace at Commerce Municipal Airport (78 FR 33019... U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec....

  5. 75 FR 8491 - Security Zones; Brazos River, Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ...; Brazos River, Freeport, TX in the Federal Register (74 FR 61305). We received no comments on the proposed... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zones; Brazos River, Freeport, TX AGENCY: Coast Guard, DHS. ACTION: Final rule. SUMMARY: The Coast Guard has established four permanent security...

  6. Registration of sorghum germplasm Tx3408 and Tx3409 with tolerance to sugarcane aphid [Melanaphis saccari (Zehntner)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The sorghum (Sorghum bicolor L. Moench) germplasm lines Tx3408 and Tx3409 were developed and released from Texas A&M AgriLife Research and the USDA-ARS in 2015. Both of these lines were developed from intentional crosses using the pedigree method of plant breeding. The breeding crosses for these l...

  7. 76 FR 5120 - Television Broadcasting Services; El Paso, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... From the Federal Register Online via the Government Publishing Office ] FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications... 73 Television, Television broadcasting. For the reasons discussed in the preamble, the...

  8. Antibacterial Activity of Ti₃C₂Tx MXene.

    PubMed

    Rasool, Kashif; Helal, Mohamed; Ali, Adnan; Ren, Chang E; Gogotsi, Yury; Mahmoud, Khaled A

    2016-03-22

    MXenes are a family of atomically thin, two-dimensional (2D) transition metal carbides and carbonitrides with many attractive properties. Two-dimensional Ti3C2Tx (MXene) has been recently explored for applications in water desalination/purification membranes. A major success indicator for any water treatment membrane is the resistance to biofouling. To validate this and to understand better the health and environmental impacts of the new 2D carbides, we investigated the antibacterial properties of single- and few-layer Ti3C2Tx MXene flakes in colloidal solution. The antibacterial properties of Ti3C2Tx were tested against Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis) by using bacterial growth curves based on optical densities (OD) and colonies growth on agar nutritive plates. Ti3C2Tx shows a higher antibacterial efficiency toward both Gram-negative E. coli and Gram-positive B. subtilis compared with graphene oxide (GO), which has been widely reported as an antibacterial agent. Concentration dependent antibacterial activity was observed and more than 98% bacterial cell viability loss was found at 200 μg/mL Ti3C2Tx for both bacterial cells within 4 h of exposure, as confirmed by colony forming unit (CFU) and regrowth curve. Antibacterial mechanism investigation by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) coupled with lactate dehydrogenase (LDH) release assay indicated the damage to the cell membrane, which resulted in release of cytoplasmic materials from the bacterial cells. Reactive oxygen species (ROS) dependent and independent stress induction by Ti3C2Tx was investigated in two separate abiotic assays. MXenes are expected to be resistant to biofouling and offer bactericidal properties.

  9. 77 FR 32900 - Radio Broadcasting Services; Llano, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Llano, TX AGENCY: Federal Communications Commission... Congressional Review Act, see U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting...: PART 73--RADIO BROADCAST SERVICES 0 1. The authority citation for part 73 continues to read as...

  10. 77 FR 58800 - Radio Broadcasting Services; Knox City, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Knox City, TX AGENCY: Federal Communications....415 and 1.420. ] List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications... preamble, the Federal Communications Commission proposes to amend 47 CFR part 73 as follows: PART...

  11. 76 FR 36384 - Radio Broadcasting Services; Brackettville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ... Making proposed the deletion of vacant Channel 234A at Brackettville. See 75 FR 4037, published January... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Brackettville, TX AGENCY: Federal Communications..., see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting....

  12. 78 FR 21337 - Radio Broadcasting Services; Matagorda, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Matagorda, TX AGENCY: Federal Communications....415 and 1.420. List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications... preamble, the Federal Communications Commission proposes to amend 47 CFR Part 73 as follows: PART...

  13. 77 FR 25112 - Radio Broadcasting Services; Centerville and Midway, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Centerville and Midway, TX AGENCY: Federal... filing procedures for comments, see 47 CFR 1.415 and 1.420. List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications Commission. Nazifa Sawez, Assistant Chief, Audio...

  14. 78 FR 4078 - Radio Broadcasting Services; Hebbronville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Hebbronville, TX AGENCY: Federal Communications... Review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Radio, Radio broadcasting...: PART 73--RADIO BROADCAST SERVICES 0 1. The authority citation for part 73 continues to read as...

  15. Spectroscopic Classification of ASASSN-15tx as a CV

    NASA Astrophysics Data System (ADS)

    Bersier, D.; Copperwheat, C.

    2015-12-01

    We report a spectroscopic observation of ASASSN-15tx (ATel #8400) obtained with the 2m robotic Liverpool Telescope (+SPRAT low-resolution spectrograph) on 2015 Dec 11.9078 UT. The spectrum, covering the 400-800 nm range, is blue and nearly featureless.

  16. Service with Style: Corinne Hill--Denton Public Library, TX

    ERIC Educational Resources Information Center

    Library Journal, 2004

    2004-01-01

    Although a librarian for only eight years, Corinne Hill is already known in Dallas and Denton, TX, for turning dull, little-used branches into vibrant community centers. A stylish woman with a zest for shopping, Hill loves developing new collections and showing them off. She sees no reason why a library should not be as attractive as any good…

  17. 76 FR 58556 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-21

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2... completed loan applications to: U.S. Small Business Administration, Processing and Disbursement...

  18. 75 FR 65227 - Revocation of Class E Airspace; Franklin, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... rulemaking to remove Class E airspace for Franklin, TX (75 FR 36586) Docket No. FAA-2010-0603. Interested... read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not...

  19. 75 FR 13668 - Amendment of Class E Airspace; Georgetown, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71... Airport, Georgetown, TX (74 ] FR 67142) Docket No. FAA-2009-0934. Interested parties were invited to... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44...

  20. 75 FR 18776 - Regulated Navigation Area; Galveston Channel, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ..., 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA11 Regulated Navigation Area; Galveston Channel, TX AGENCY... a regulated navigation area across the entire width of the Galveston Channel in the vicinity...

  1. 78 FR 41839 - Establishment of Class E Airspace; Presidio, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The... the Presidio, TX, area, creating controlled airspace at Presidio Lely International Airport (78 FR... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3)...

  2. 78 FR 61179 - Establishment of Class E Airspace; Comanche, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Comanche, TX...

  3. 78 FR 18801 - Establishment of Class E Airspace; Beeville, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp... Airport, Beeville, TX (77 FR 71365) Docket No. FAA- 2012-0821. Interested parties were invited to... 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...

  4. 75 FR 13669 - Amendment of Class E Airspace; Dumas, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ..., Dumas, TX (74 FR 68747) Docket No. FAA-2009-1151. Interested parties were invited to participate in this... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565,...

  5. 76 FR 44280 - Television Broadcasting Services; El Paso, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ... COMMISSION 47 CFR Part 73 Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications... 12, 2009 digital transition deadline, after which the Video Division granted KVIA-TV Special... channel substitution will serve the public interest by significantly improving the public's digital...

  6. 75 FR 19907 - Television Broadcasting Services; Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... COMMISSION 47 CFR Part 73 Television Broadcasting Services; Beaumont, TX AGENCY: Federal Communications... Broadcasting of Texas, the licensee of KFDM(TV), channel 21, Beaumont, Texas, requesting the substitution of... broadcasting. 0 For the reasons discussed in the preamble, the Federal Communications Commission amends 47...

  7. 75 FR 9859 - Television Broadcasting Services; Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... COMMISSION 47 CFR Part 73 Television Broadcasting Services; Beaumont, TX AGENCY: Federal Communications... Freedom Broadcasting of Texas (``Freedom Broadcasting''), the licensee of KFDM(TV), channel 21, Beaumont, Texas. Freedom Broadcasting requests ] the substitution of channel 25 for channel 21 at Beaumont....

  8. 75 FR 11000 - Security Zone; Freeport LNG Basin, Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... Federal Register (33 FR 19926). We received no comments on the proposed rule. Background and Purpose... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zone; Freeport LNG Basin, Freeport, TX AGENCY... in the Freeport LNG Basin. This security zone is needed to protect vessels, waterfront...

  9. 76 FR 19276 - Television Broadcasting Services; El Paso, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications... U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television. Federal...

  10. 76 FR 28946 - Television Broadcasting Services; El Paso, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications... CFR 1.415 and 1.420. List of Subjects in 47 CFR Part 73 Television Federal Communications...

  11. 76 FR 62131 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1... only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08... organizations in the State of TEXAS, dated 09/21/2011, is hereby amended to include the following areas...

  12. 76 FR 79750 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 4... Only for the State of Texas (FEMA- 1999-DR), dated 08/15/2011. Incident: Wildfires. Incident Period: 04... Non-Profit organizations in the State of Texas, dated 08/15/2011, is hereby amended to include...

  13. 75 FR 57997 - Texas Disaster Number TX-00361

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... ADMINISTRATION Texas Disaster Number TX-00361 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 08/03/2010 is hereby amended to include the...

  14. 76 FR 59766 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  15. 76 FR 70528 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 5... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011 . Incident: Wildfires. Incident Period... Non-Profit organizations in the State of Texas, dated 09/21/2011, is hereby amended to include...

  16. 76 FR 77298 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 8. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... major disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to extend...

  17. 76 FR 61775 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... ADMINISTRATION [Disaster Declaration 12815 and 12816 Texas Disaster Number TX-00381 AGENCY: U.S. Small Business... disaster for the State of Texas (FEMA-4029-DR), dated 09/09/2011. Incident: Wildfires. Incident Period: 08... INFORMATION: The notice of the Presidential disaster declaration for the State of Texas, dated 09/09/2011...

  18. 75 FR 52789 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3... Only for the State of TEXAS (FEMA- 1931-DR), dated 08/03/2010. Incident: Hurricane Alex. Incident... Private Non-Profit organizations in the State of Texas, dated 08/03/2010, is hereby amended to include...

  19. 76 FR 54521 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1... Only for the State of Texas (FEMA- 1999-DR), dated 08/15/2011. Incident: Wildfires. Incident Period: 04... Non-Profit organizations in the State of TEXAS, dated 08/15/2011, is hereby amended to include...

  20. 76 FR 64420 - TEXAS Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... ADMINISTRATION TEXAS Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 6. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of TEXAS... disaster declaration for the State of TEXAS, dated 09/09/2011 is hereby amended to include the...

  1. 76 FR 63699 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08... organizations in the State of Texas, dated 09/21/2011, is hereby amended to include the following areas...

  2. 76 FR 68804 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 4... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. >Incident Period... organizations in the State of Texas, dated 09/21/2011, is hereby amended to include the following areas...

  3. 75 FR 55618 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 4... Only for the State of Texas (FEMA- 1931-DR), dated 08/03/2010. Incident: Hurricane Alex. Incident... Non-Profit organizations in the State of Texas, dated 08/03/2010, is hereby amended to include...

  4. 76 FR 79751 - Texas Disaster Number TX-00380

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... ADMINISTRATION Texas Disaster Number TX-00380 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3... Only for the State of Texas (FEMA- 1999-DR), dated 08/15/2011. Incident: Wildfires. Incident Period: 04... Non-Profit organizations in the State of Texas, dated 08/15/2011, is hereby amended to...

  5. 77 FR 1546 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 9. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... major disaster ] declaration for the State of Texas, dated 09/09/2011 is hereby amended to establish...

  6. 76 FR 67244 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-31

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 7. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... major disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to extend...

  7. 75 FR 52788 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2... Only for the State of Texas (FEMA- 1931-DR), dated 08/03/2010. Incident: Hurricane Alex. Incident... Private Non-Profit organizations in the State of TEXAS, dated 08/03/2010, is hereby amended to...

  8. 76 FR 59480 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-26

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  9. 76 FR 66109 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 3... Only for the State of Texas (FEMA--4029--DR), dated 09/21/2011. Incident: Wildfires. Incident Period... organizations in the State of Texas, dated 09/21/2011, is hereby amended to include the following areas...

  10. 77 FR 1547 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 6... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. Incident Period: 08... Non-Profit organizations in the State of Texas, dated 09/21/2011, is hereby amended to establish...

  11. 75 FR 51293 - Texas Disaster Number TX-00362

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-19

    ... ADMINISTRATION Texas Disaster Number TX-00362 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1... Only for the State of Texas (FEMA- 1931-DR), dated 08/03/2010 . Incident: Hurricane Alex. Incident... Non-Profit organizations in the State of TEXAS, dated 08/03/2010, is hereby amended to include...

  12. 76 FR 62130 - Texas Disaster Number TX-00381

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-06

    ... ADMINISTRATION Texas Disaster Number TX-00381 AGENCY: U.S. Small Business Administration. ACTION: Amendment 5. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... disaster declaration for the State of Texas, dated 09/09/2011 is hereby amended to include the...

  13. 77 FR 7228 - Texas Disaster Number TX-00382

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... ADMINISTRATION Texas Disaster Number TX-00382 AGENCY: U.S. Small Business Administration. ACTION: Amendment 7... Only for the State of Texas (FEMA- 4029-DR), dated 09/21/2011. Incident: Wildfires. ] Incident Period... Non-Profit organizations in the State of TEXAS, dated 09/21/2011, is hereby amended to include...

  14. 75 FR 52789 - Texas Disaster Number TX-00361

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... ADMINISTRATION Texas Disaster Number TX-00361 AGENCY: U.S. Small Business Administration. ACTION: Amendment 1. SUMMARY: This is an amendment of the Presidential declaration of a major disaster for the State of Texas... the President's major disaster declaration for the State of TEXAS, dated 08/03/2010 is hereby...

  15. 75 FR 31677 - Amendment of Class E Airspace; Austin, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ..., TX area, reconfiguring controlled airspace at Austin Executive Airport (75 FR 15360) Docket No. FAA... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2....

  16. 75 FR 8489 - Security Zone; Freeport Channel Entrance, Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... Security Zone; Freeport Channel Entrance, Freeport, TX in the Federal Register (33 FR 19923). We received... rule as it was proposed in the notice of proposed rulemaking (33 FR 19923). Regulatory Analyses We... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA87 Security Zone; Freeport Channel Entrance, Freeport,...

  17. 75 FR 8483 - Amendment of Class E Airspace; Llano, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... Airport, Llano, TX (74 FR 52702) Docket No. FAA-2009-0858. Interested parties were invited to participate... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and...

  18. 75 FR 41119 - Special Local Regulations; Sabine River, Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ..., 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Sabine River, Orange, TX... River, Orange, Texas. This Special Local Regulation is intended to restrict vessels from portions of...

  19. 76 FR 30890 - Special Local Regulations; Sabine River, Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting. But you may... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations; Sabine River, Orange, TX... River, Orange, Texas on September 24-25, 2011. This Special Local Regulation is intended to...

  20. 75 FR 55968 - Special Local Regulations, Sabine River; Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... (NPRM) entitled Special Local Regulations; Sabine River, Orange, TX in the Federal Register (75 FR 41119... published in 75 FR 41119. Regulatory Analyses We developed this rule after considering numerous statutes and... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulations, Sabine River; Orange,...

  1. MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity.

    PubMed

    Rosso, Jean-Pierre; Schwarz, Jürgen R; Diaz-Bustamante, Marcelo; Céard, Brigitte; Gutiérrez, José M; Kneussel, Matthias; Pongs, Olaf; Bosmans, Frank; Bougis, Pierre E

    2015-02-24

    GABAA receptors shape synaptic transmission by modulating Cl(-) conductance across the cell membrane. Remarkably, animal toxins that specifically target GABAA receptors have not been identified. Here, we report the discovery of micrurotoxin1 (MmTX1) and MmTX2, two toxins present in Costa Rican coral snake venom that tightly bind to GABAA receptors at subnanomolar concentrations. Studies with recombinant and synthetic toxin variants on hippocampal neurons and cells expressing common receptor compositions suggest that MmTX1 and MmTX2 allosterically increase GABAA receptor susceptibility to agonist, thereby potentiating receptor opening as well as desensitization, possibly by interacting with the α(+)/β(-) interface. Moreover, hippocampal neuron excitability measurements reveal toxin-induced transitory network inhibition, followed by an increase in spontaneous activity. In concert, toxin injections into mouse brain result in reduced basal activity between intense seizures. Altogether, we characterized two animal toxins that enhance GABAA receptor sensitivity to agonist, thereby establishing a previously unidentified class of tools to study this receptor family.

  2. MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity

    PubMed Central

    Rosso, Jean-Pierre; Schwarz, Jürgen R.; Diaz-Bustamante, Marcelo; Céard, Brigitte; Gutiérrez, José M.; Kneussel, Matthias; Pongs, Olaf; Bosmans, Frank; Bougis, Pierre E.

    2015-01-01

    GABAA receptors shape synaptic transmission by modulating Cl− conductance across the cell membrane. Remarkably, animal toxins that specifically target GABAA receptors have not been identified. Here, we report the discovery of micrurotoxin1 (MmTX1) and MmTX2, two toxins present in Costa Rican coral snake venom that tightly bind to GABAA receptors at subnanomolar concentrations. Studies with recombinant and synthetic toxin variants on hippocampal neurons and cells expressing common receptor compositions suggest that MmTX1 and MmTX2 allosterically increase GABAA receptor susceptibility to agonist, thereby potentiating receptor opening as well as desensitization, possibly by interacting with the α+/β− interface. Moreover, hippocampal neuron excitability measurements reveal toxin-induced transitory network inhibition, followed by an increase in spontaneous activity. In concert, toxin injections into mouse brain result in reduced basal activity between intense seizures. Altogether, we characterized two animal toxins that enhance GABAA receptor sensitivity to agonist, thereby establishing a previously unidentified class of tools to study this receptor family. PMID:25675485

  3. The symbiotic star TX CVn has entered an active state

    NASA Astrophysics Data System (ADS)

    Munari, U.; Castellani, F.; Valisa, P.; Dallaporta, S.; Cherini, G.; Vagnozzi, A.; Righetti, G. L.; Belligoli, R.

    2014-01-01

    After the last active phase that begun in 2003, the symbiotic star TX CVn has now entered a new active phase. In 2003, TX CVn rose to B=10.5 and there it remained until the end of 2007 (Skopal 2007, AN 328, 909), when we started monitoring the variable with various ANS Collaboration telescopes in BVRI bands. Our observations show that the star has spent the following 6 years on a steady decline at a rate of 0.084 mag per year in the B band, that took it from B=10.55 on December 2007 to B=11.02 on September 2013, when the star begun a rapid brightening, reaching B=10.65 by early December 2013.

  4. Tank 241-TX-302C grab samples 302C-TX-97-1A through 302C-TX-97-3B analytical results for the final report

    SciTech Connect

    Esch, R.A.

    1998-03-12

    This document is the final report for tank 241-TX-302C grab samples. Six grabs samples (302C-TX-97-1A, 302C-TX-97-1B, 302C-TX-97-2A, 302C-TX-97-2B, 302C-TX-97-3A, and 302C-TX-97-3B) were collected from the catch tank level gauge riser on December 19, 1997. The ``A`` and ``B`` portions from each sample location were composited and analyses were performed on the composites in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1997) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Rev. 1: Fowler, 1995; Rev. 2: Mulkey and Miller, 1997). The analytical results are presented in Table 1. No notification limits were exceeded. Appearance and Sample Handling Attachment 1 is provided as a cross-reference for relating the tank farm customer identification numbers with the 222-S Laboratory sample numbers and the portion of sample analyzed. Table 2 provides the appearance information.

  5. 77 FR 74170 - Foreign-Trade Zone 84-Houston, TX; Notification of Proposed Production Activity; Mitsubishi...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ...; Mitsubishi Caterpillar Forklift America Inc.; (Forklift Trucks); Houston, TX The Port of Houston Authority... Caterpillar Forklift America Inc. (MCFA), located in Houston, Texas. The notification conforming to...

  6. 60-day waste compatibility safety issues and final results for TX-244 grab samples

    SciTech Connect

    Nuzum, J.L., Fluor Daniel Hanford

    1997-02-05

    Three grab samples (244-TX-96-1, 244-TX-96-2, and 244-TX-96-3) were taken from Riser 8 of Tank 241-TX-244 on October 18, 1996, and received by 222-S Laboratory on October 18, 1996. These samples were analyzed in accordance with Compatibility Grab Sampling and Analysis Plan (TSAP) and Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) in support ofthe Waste Compatibility Program. Notifications were made in accordance with TSAP for pH and OH- analyses. Upon further review, the pH notification was deemed unnecessary, as the notification limit did not apply to this tank.

  7. Variability of ultraviolet emission in the carbon star TX Piscium

    NASA Technical Reports Server (NTRS)

    Johnson, Hollis R.; Baumert, John H.; Querci, Francois; Querci, Monique

    1986-01-01

    Multiple low-resolution IUE observations of the cool carbon star TX Psc (N0; C6, 2) permit an analysis of the variations in strength of the strongest emission lines - the Mg II line at 2800 A, the C II line at 2330 A, and certain Fe II lines. The integrated flux of the Mg II line varied by at least a factor of eight, while that of the C II line varies by at least a factor of five. The variations in Fe II may be considerably larger. The lines appear to vary together. The continuous flux in the best observed range from 2800 to 3200 A does not vary noticeably.

  8. Staubli TX-90XL robot qualification at the LLIHE.

    SciTech Connect

    Covert, Timothy Todd

    2010-10-01

    The Light Initiated High Explosive (LIHE) Facility uses a robotic arm to spray explosive material onto test items for impulse tests. In 2007, the decision was made to replace the existing PUMA 760 robot with the Staubli TX-90XL. A qualification plan was developed and implemented to verify the safe operating conditions and failure modes of the new system. The robot satisfied the safety requirements established in the qualification plan. A performance issue described in this report remains unresolved at the time of this publication. The final readiness review concluded the qualification of this robot at the LIHE facility.

  9. 76 FR 77245 - Attwater Prairie Chicken National Wildlife Refuge, Austin and Colorado Counties, TX...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... process through a notice in the Federal Register (73 FR 65871; November 5, 2008). The Attwater Prairie... conservation plan and environmental assessment (EA) in the Federal Register on November 5, 2008 (73 FR 65871... opportunities for wildlife observation and photography, and environmental education and interpretation. We...

  10. 77 FR 47660 - Attwater Prairie Chicken National Wildlife Refuge, Austin and Colorado Counties, TX; Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... started this process through a notice in the Federal Register (73 FR 65871; November 5, 2008). We released... in the Federal Register (76 FR 77245; December 12, 2011). The Attwater Prairie Chicken NWR, which... for hunting, fishing, wildlife observation and photography, and environmental education...

  11. 77 FR 65011 - Buffalo Lake National Wildlife Refuge, Randall County, TX; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-24

    ... 23, 2012. We will announce upcoming public meetings in local news media. ADDRESSES: You may submit... this process through a notice in the Federal Register (63 FR 33693; June 19, 1998). The Buffalo Lake..., including opportunities for wildlife observation and photography, and environmental education...

  12. 77 FR 64541 - Trinity River National Wildlife Refuge, Liberty County, TX; Final Comprehensive Conservation Plan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... process for Trinity River NWR. We started this process through a notice in the Federal Register (72 FR... comments in a notice of availability in the Federal Register (77 FR 18853-18856; March 28, 2012). The..., including opportunities for hunting, fishing, wildlife observation and photography, and...

  13. 77 FR 18853 - Trinity River National Wildlife Refuge, Liberty County, TX; Comprehensive Conservation Plan and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... will announce upcoming public meetings in local news media. ADDRESSES: You may submit comments or... this process through a notice in the Federal Register (72 FR 45059; August 10, 2007). The Trinity River... opportunities available to the public, including opportunities for wildlife observation and photography,...

  14. 75 FR 6872 - Aransas National Wildlife Refuge Complex, Aransas, Calhoun, and Refugio Counties, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-12

    ... upcoming public meetings in local news media. ADDRESSES: You may submit comments or requests for copies or... notice in the Federal Register (67 FR 55862, August 30, 2002). Aransas NWRC is located in Aransas..., Aransas NWRC contains critical habitat for the whooping crane (43 FR 20938, May 15, 1978). Background...

  15. 76 FR 5196 - Aransas National Wildlife Refuge Complex, Aransas, Calhoun, and Refugio Counties, TX; Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... opportunities for hunting, fishing, wildlife observation and photography, and environmental education and... current levels. Visitor facilities and interpretive and environmental education programs would be improved...-dependent recreation activities, such as hunting, fishing, wildlife observation, photography,...

  16. 77 FR 40901 - Notice of Inventory Completion: Gregg County Historical Museum, Longview, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... from Burial 6 include an occipital cranial bone fragment of one adult of unknown sex. The human remains... human medial cuneiform and other bone fragments of one individual of unknown age and sex. The human... include 16 long bone fragments of one individual of unknown age and sex. The human remains from Burial...

  17. 77 FR 40897 - Notice of Intent to Repatriate Cultural Items: Gregg County Historical Museum, Longview, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... ceramic vessels, 8 arrow points (of the Perdiz style), 3 ceramic pipe sherds, and 1 glass bead. The Henry... funerary objects are 19 ceramic vessels and 1 blue glass bead. The Lot 5 collection dates to A.D. 1450-1680... unassociated funerary objects are 1 lot of approximately 8,267 glass beads, 250 ceramic vessels, and 24...

  18. Observations of HCN associated with TX Cam and IK Tau

    NASA Astrophysics Data System (ADS)

    Marvel, K. B.

    1999-12-01

    I present observations of HCN associated with the oxygen-rich stars TX Cam and IK Tau. These observations were obtained with the Owens Valley Radio Observatory millimeter array telescope, funded in part by the National Science Foundation. The distribution of HCN near these evolved stars is generally spherical in nature although mildly asymmetric. The emission is optically thick and therefore quantitative interpretation is difficult. It is clear from the images that the HCN is centrally peaked in every channel and clearly does not exist in a shell-like distribution. The overall diameter of the emission is about 750 AU for IK Tau and 940 AU for TX Cam, assuming distances of 260 pc (Loup et al. 1993) and 280 pc (Knapp et al. 1998) respectively. How oxygen-rich stars can exhibit emission from carbon-based molecules has long challenged chemical models for these sources. Charnley et al. (1995) proposed a chemical model, which also predicted the presence of C2H and CH3OH in detectable quantities. Charnley et al. (1997) subsequently used the NRAO 12-m to show that these molecules do not exist in detectable quantities near these stars. I confirm this result using interferometric observations, which are more sensitive to compact distributions of gas.

  19. Modal testing of the TX-100 wind turbine blade.

    SciTech Connect

    Reese, Sarah; Griffith, Daniel Todd; Casias, Miguel; Simmermacher, Todd William; Smith, Gregory A.

    2006-05-01

    This test report covers the SNL modal test results for two nominally identical TX-100 wind turbine blades. The TX-100 blade design is unique in that it features a passive braking, force-shedding mechanism where bending and torsion are coupled to produce desirable aerodynamic characteristics. A specific aim of this test is to characterize the coupling between bending and torsional dynamics. The results of the modal tests and the subsequent analysis characterize the natural frequencies, damping, and mode shapes of the individual blades. The results of this report are expected to be used for model validation--the frequencies and mode shapes from the experimental analysis can be compared with those of a finite-element analysis. Damping values are included in the results of these tests to potentially improve the fidelity of numerical simulations, although numerical finite element models typically have no means of predicting structural damping characteristics. Thereafter, an additional objective of the test is achieved in evaluating the test to test and unit variation in the modal parameters of the two blades.

  20. 78 FR 33019 - Proposed Amendment of Class E Airspace; Commerce, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; Commerce, TX AGENCY... action proposes to amend Class E airspace at Commerce, TX. Additional controlled airspace is necessary to... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR,...

  1. 78 FR 55214 - Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-10

    ... SECURITY Coast Guard 33 CFR Part 100 Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast.... Coast Guard Marine Safety Unit Port Arthur, TX; telephone 409-719-5086, email...

  2. 77 FR 47519 - Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... SECURITY Coast Guard 33 CFR Part 100 Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of regulation. SUMMARY: The Coast..., call or email Mr. Scott Whalen. U.S. Coast Guard Marine Safety Unit Port Arthur, TX; telephone...

  3. 78 FR 31839 - Establishment of Class E Airspace; Beeville-Chase Field, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-28

    ... page 18801, column 2, line 14, the title as published in the Federal Register of March 28, 2013 (78 FR 18801) FR Doc. 2013-06913, is corrected to read `` . . . Beeville-Chase Field, TX''; and on page 18802... Industrial Airport, Beeville, TX (78 FR 18801, March 28, 2013). Subsequent to publication, the FAA found...

  4. 75 FR 39149 - Establishment of Low Altitude Area Navigation Route (T-284); Houston, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... Federal Register a final rule to establish RNAV route T-284 for the Houston, TX, terminal area (75 FR... Federal Aviation Administration 14 CFR Part 71 RIN 2120-AA66 Establishment of Low Altitude Area Navigation... area navigation (RNAV) route T-284 for the Houston, TX, terminal area, is being withdrawn. As a...

  5. Registration of perennial Sorghum bicolor x S. propinquum line 'PSH12TX09'

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A novel sorghum x Sorghum propinquum recombinant inbred line, named PSSH12TX09, was identified that successfully overwintered across plant hardiness zones 8a, 8b, and 9a between 2013 and 2015. Overwintering perenniality of PSSH12TX09 exceeded 90% at all locations across both evaluation years, with ...

  6. 78 FR 28801 - Foreign-Trade Zone 117-Orange, TX, Authorization of Production Activity, Signal International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ... notice in the Federal Register inviting public comment (78 FR 4383, 1-22-2013). The FTZ Board has... Foreign-Trade Zones Board Foreign-Trade Zone 117--Orange, TX, Authorization of Production Activity, Signal International Texas GP, LLC (Shipbuilding), Orange, TX On January 10, 2013, the Foreign Trade Zone of...

  7. CX-100 and TX-100 blade field tests.

    SciTech Connect

    Holman, Adam (USDA-Agriculture Research Service, Bushland, TX); Jones, Perry L.; Zayas, Jose R.

    2005-12-01

    In support of the DOE Low Wind Speed Turbine (LWST) program two of the three Micon 65/13M wind turbines at the USDA Agricultural Research Service (ARS) center in Bushland, Texas will be used to test two sets of experimental blades, the CX-100 and TX-100. The blade aerodynamic and structural characterization, meteorological inflow and wind turbine structural response will be monitored with an array of 75 instruments: 33 to characterize the blades, 15 to characterize the inflow, and 27 to characterize the time-varying state of the turbine. For both tests, data will be sampled at a rate of 30 Hz using the ATLAS II (Accurate GPS Time-Linked Data Acquisition System) data acquisition system. The system features a time-synchronized continuous data stream and telemetered data from the turbine rotor. This paper documents the instruments and infrastructure that have been developed to monitor these blades, turbines and inflow.

  8. Chemical Contamination of the Lower Rio Grande near Laredo, TX

    NASA Astrophysics Data System (ADS)

    Flores, B.; Ren, J.; Krishnamurthy, S.; Belzer, W.

    2006-12-01

    The Rio Grande River stretches over 2000 miles from the southern Rocky Mountains in Colorado to the tip of Texas where the Rio Grande meets the Gulf of Mexico. It is the natural boundary between U.S. and Mexico from El Paso, TX, to Brownsville, TX. The communities along the border heavily rely upon the Rio Grande as a primary source of water for consumption, agricultural uses, supporting wildlife and recreation. For many years the Rio Grande has been polluted with municipal, industrial, agricultural and farming contaminants from both sides of the border. This pollution has led to the extinction or reduction of certain wildlife species as well as affecting the health of the residences along the border. Even though great strides have been made in monitoring the Rio Grande, there has been a lack of intense monitoring data collection for pollutants such as pesticides. Three sampling sites including Manadas Creek, the Rio Grande River at International Bridge I, and USGS monitoring site 08459200 off of Highway 83 were chosen. The water quality parameters focused include temperature, pH, conductivity, dissolve oxygen (DO), salinity, total dissolved solids, nutrients, metals and pesticides. Preliminary results have shown elevated concentration of total phosphorus and ortho-phosphorus in the Manadas Creek site. Organochlorinated pesticides such as heptachlor and 4, 4 DDE were detected at various concentrations at all sites and endrin aldehyde was found at Manadas Creek site. This research has provided more information on the current chemical contamination level of the Rio Grande in the Laredo area.

  9. 33 CFR 165.809 - Security Zones; Port of Port Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zones; Port of Port Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi Inner Harbor, Corpus Christi, TX. 165... Lavaca-Point Comfort, Point Comfort, TX and Port of Corpus Christi Inner Harbor, Corpus Christi, TX....

  10. Tank characterization report for single-shell tank 241-TX-107

    SciTech Connect

    Sasaki, L.M., Westinghouse Hanford

    1996-07-10

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-TX-107. This report supports the requirements of Tri-party Agreement Milestone M-44-09.

  11. Kinetics of Crystal Violet Fading in the Presence of TX-100, DTAB and SDS.

    PubMed

    Samiey, Babak; Ashoori, Fatemeh

    2011-06-01

    The rate constant of alkaline fading of crystal violet (CV+) was measured in the presence of non ionic (TX-100), cationic (DTAB) and anionic (SDS) surfactants. This reaction was studied at 283-303 K. The rate of reaction showed remarkable dependence on the electrical charge of the used surfactants. It was observed that the reaction rate constant increased in the presence of TX-100 and DTAB and decreased in the presence of SDS. Binding constants of CV+ with TX-100 and DTAB and the related thermodynamic parameters were obtained by classical (or stoichiometric) model. The results show that binding of CV+ to TX-100 is endothermic and binding of CV+ to DTAB and SDS is exothermic in the used concentration range of surfactants.

  12. Fate of the Biological Control Agent Pseudomonas aureofaciens TX-1 after Application to Turfgrass†

    PubMed Central

    Sigler, William V.; Nakatsu, Cindy H.; Reicher, Zachary J.; Turco, Ronald F.

    2001-01-01

    The fate and impact of Pseudomonas aureofaciens TX-1 following application as a biocontrol agent for fungi in turfgrass were studied. The organism was applied with a modified irrigation system by using a preparation containing 1 × 106 P. aureofaciens TX-1 CFU ml−1 about 100 times between May and August. We examined the impact of this repeated introduction of P. aureofaciens TX-1 (which is known to produce the antimicrobial compound phenazine-1-carboxylic acid) on the indigenous microbial community of the turfgrass system and on establishment of introduced bacteria in the soil system. A PCR primer-DNA hybridization probe combination was developed to accurately monitor the fate of P. aureofaciens TX-1 following application in irrigation water. To assess the impact of frequent P. aureofaciens TX-1 applications on the indigenous bacterial community, turfgrass canopy, thatch, and rhizosphere samples were obtained during the growing season from control and treated plots and subjected to DNA extraction procedures and denaturing gradient gel electrophoresis (DGGE). PCR amplification and hybridization of extracted DNA with the P. aureofaciens TX-1-specific primer-probe combination revealed that P. aureofaciens TX-1 not only became established in the rhizosphere and thatch but also was capable of overwintering. Separation of PCR-amplified partial 16S rRNA genes by DGGE showed that the repeated application of P. aureofaciens TX-1 in irrigation water resulted in transient displacement of a leaf surface bacterial community member. There was no obvious alteration of any dominant members of the thatch and rhizosphere microbial communities. PMID:11472930

  13. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2011-10-01 2011-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  14. 46 CFR 7.105 - Marquesas Keys, FL to Rio Grande, TX.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the seaward limits of the territorial sea (as defined in 33 CFR 2.22(a)(1)) to Rio Grande, Texas at... 46 Shipping 1 2010-10-01 2010-10-01 false Marquesas Keys, FL to Rio Grande, TX. 7.105 Section 7... LINES Gulf Coast § 7.105 Marquesas Keys, FL to Rio Grande, TX. A line drawn from Marquesas Keys,...

  15. Characterization of in vitro oxidative and conjugative metabolic pathways for brevetoxin (PbTx-2).

    PubMed

    Radwan, Faisal F Y; Ramsdell, John S

    2006-01-01

    Brevetoxins are potent marine toxins produced by the dinoflagellate Karenia brevis, the causative organism of Florida red tides. An in vitro metabolism of PbTx-2 was performed using purified cDNA-expressed rat liver cytochrome P-450 (CYP) enzymes and freshly isolated rat hepatocytes. The metabolic activities of six CYP enzymes, CYP1A2, CYP2A2, CYP2C11, CYP2D1, CYP2E1, and CYP3A1, were examined by incubation with PbTx-2 for up to 4 h in the presence of a NADPH-generating system. Further identification of the metabolites produced by CYP1A2 and CYP3A1 was preformed using high performance liquid chromatography-mass spectrometry (LC/MS). Both CYP1A2 and CYP3A1 metabolized PbTx-2 to PbTx-3 (MH+: m/z 897), PbTx-9 (MH+: m/z 899), and a newly recorded diol brevetoxin-2 metabolite (MH+: m/z 929). CYP3A1 also produced a considerably higher amount of BTX-B5 (MH+: m/z 911). Subsequent incubation of PbTx-2 with rat hepatocytes produced additional phase 1 metabolites of MH+: m/z 911, 913, 915, 917, and 931, indicating a CYP-catalyzed epoxidation at H-ring (C27,C28-double bond) and a subsequent A-ring hydrolysis of PbTx-2 metabolic products. A conjugation metabolism was identified by the production of a glutathione-brevetoxin conjugate (MH+: m/z 1222) and a cysteine-brevetoxin conjugate (MH+: m/z 1018). Structures of the new metabolites are postulated, and a likely CYP-catalyzed metabolism pathway of PbTx-2 metabolism are discussed. PMID:16221966

  16. 77 FR 66068 - Amendment of Class E Airspace; Breckenridge, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-01

    ..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation..., creating additional controlled airspace at Stephens County Airport (77 FR 50648) Docket No. FAA-2012-0653... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3)...

  17. 78 FR 48294 - Amendment of Class E Airspace; Mason, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... additional controlled airspace at Mason County Airport (78 FR 31429) Docket No. FAA-2012-1141. Interested... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does.... 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in...

  18. Synthesis and electrochemical performance of Ti3C2Tx with hydrothermal process

    NASA Astrophysics Data System (ADS)

    Wang, Libo; Zhang, Heng; Wang, Bo; Shen, Changjie; Zhang, Chuanxiang; Hu, Qianku; Zhou, Aiguo; Liu, Baozhong

    2016-09-01

    In this study, a simple hydrothermal method has been developed to prepare Ti3C2Tx from Ti3AlC2 as a high-performance electrode material for supercapacitors. This method is environmentally friendly and has a low level of danger. The morphology and structure of the Ti3C2Tx can be controlled by hydrothermal reaction time, temperature and NH4F amounts. The prepared Ti3C2Tx was characterized by X-ray diffraction, field emission scanning electron microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy and Brunauer-Emmet-Teller. The results show that the prepared Ti3C2Tx is terminated by O, OH, and F groups. The electrochemical properties of the Ti3C2Tx sample exhibit specific capacitance up to 141 Fcm-3 in 3 M KOH aqueous electrolyte, and even after 1000 cycles, no significant degradation of the volumetric capacitance was observed. These results indicate that the Ti3C2Tx material prepared by this hydrothermal method can be used in high performance supercapacitors.

  19. Synthesis and electrochemical performance of Ti3C2Tx with hydrothermal process

    NASA Astrophysics Data System (ADS)

    Wang, Libo; Zhang, Heng; Wang, Bo; Shen, Changjie; Zhang, Chuanxiang; Hu, Qianku; Zhou, Aiguo; Liu, Baozhong

    2016-08-01

    In this study, a simple hydrothermal method has been developed to prepare Ti3C2Tx from Ti3AlC2 as a high-performance electrode material for supercapacitors. This method is environmentally friendly and has a low level of danger. The morphology and structure of the Ti3C2Tx can be controlled by hydrothermal reaction time, temperature and NH4F amounts. The prepared Ti3C2Tx was characterized by X-ray diffraction, field emission scanning electron microscopy, Raman spectroscopy, X-ray photoelectron spectroscopy and Brunauer-Emmet-Teller. The results show that the prepared Ti3C2Tx is terminated by O, OH, and F groups. The electrochemical properties of the Ti3C2Tx sample exhibit specific capacitance up to 141 Fcm-3 in 3 M KOH aqueous electrolyte, and even after 1000 cycles, no significant degradation of the volumetric capacitance was observed. These results indicate that the Ti3C2Tx material prepared by this hydrothermal method can be used in high performance supercapacitors. [Figure not available: see fulltext.

  20. Backwater Flooding in San Marcos, TX from the Blanco River

    NASA Technical Reports Server (NTRS)

    Earl, Richard; Gaenzle, Kyle G.; Hollier, Andi B.

    2016-01-01

    Large sections of San Marcos, TX were flooded in Oct. 1998, May 2015, and Oct. 2015. Much of the flooding in Oct. 1998 and Oct. 2015 was produced by overbank flooding of San Marcos River and its tributaries by spills from upstream dams. The May 2015 flooding was almost entirely produced by backwater flooding from the Blanco River whose confluence is approximately 2.2 miles southeast of downtown. We use the stage height of the Blanco River to generate maps of the areas of San Marcos that are lower than the flood peaks and compare those results with data for the observed extent of flooding in San Marcos. Our preliminary results suggest that the flooding occurred at locations more than 20 feet lower than the maximum stage height of the Blanco River at San Marcos gage (08171350). This suggest that the datum for either gage 08171350 or 08170500 (San Marcos River at San Marcos) or both are incorrect. There are plans for the U.S. Army Corps of Engineers to construct a Blanco River bypass that will divert Blanco River floodwaters approximately 2 miles farther downstream, but the $60 million price makes its implementation problematic.

  1. 77 FR 47816 - Foreign-Trade Zone 12-McAllen, TX Application for Subzone TST NA TRIM, LLC Hidalgo, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 12--McAllen, TX Application for Subzone TST NA TRIM, LLC... TST NA TRIM, LLC, located in Hidalgo, Texas. The application was submitted pursuant to the...

  2. Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom

    PubMed Central

    Lisboa, Antonio; Melaré, Rodolfo; Franco, Junia R. B.; Bis, Carolina V.; Gracia, Marta; Ponce-Soto, Luis A.; Marangoni, Sérgio; Rodrigues-Simioni, Léa; da Cruz-Höfling, Maria Alice

    2016-01-01

    Neuromuscular preparations exposed to B. marajoensis venom show increases in the frequency of miniature end-plate potentials and twitch tension facilitation followed by presynaptic neuromuscular paralysis, without evidences of muscle damage. Considering that presynaptic toxins interfere into the machinery involved in neurotransmitter release (synaptophysin, synaptobrevin, and SNAP25 proteins), the main objective of this communication is to analyze, by immunofluorescence and western blotting, the expression of the synaptic proteins, synaptophysin, synaptobrevin, and SNAP25 and by myography, light, and transmission electron microscopy the pathology of motor nerve terminals and skeletal muscle fibres of chick biventer cervicis preparations (CBC) exposed in vitro to BmjeTX-I and BmjeTX-II toxins from B. marajoensis venom. CBC incubated with toxins showed irreversible twitch tension blockade and unaffected KCl- and ACh-evoked contractures, and the positive colabelling of acetylcholine receptors confirmed that their action was primarily at the motor nerve terminal. Hypercontraction and loose myofilaments and synaptic vesicle depletion and motor nerve damage indicated that the toxins displayed both myotoxic and neurotoxic effect. The blockade resulted from interference on synaptophysin, synaptobrevin, and SNAP25 proteins leading to the conclusion that BmjeTX-I and BmjeTX-II affected neurotransmitter release machinery by preventing the docking of synaptic vesicles to the axolemma of the nerve terminal.

  3. Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom

    PubMed Central

    Lisboa, Antonio; Melaré, Rodolfo; Franco, Junia R. B.; Bis, Carolina V.; Gracia, Marta; Ponce-Soto, Luis A.; Marangoni, Sérgio; Rodrigues-Simioni, Léa; da Cruz-Höfling, Maria Alice

    2016-01-01

    Neuromuscular preparations exposed to B. marajoensis venom show increases in the frequency of miniature end-plate potentials and twitch tension facilitation followed by presynaptic neuromuscular paralysis, without evidences of muscle damage. Considering that presynaptic toxins interfere into the machinery involved in neurotransmitter release (synaptophysin, synaptobrevin, and SNAP25 proteins), the main objective of this communication is to analyze, by immunofluorescence and western blotting, the expression of the synaptic proteins, synaptophysin, synaptobrevin, and SNAP25 and by myography, light, and transmission electron microscopy the pathology of motor nerve terminals and skeletal muscle fibres of chick biventer cervicis preparations (CBC) exposed in vitro to BmjeTX-I and BmjeTX-II toxins from B. marajoensis venom. CBC incubated with toxins showed irreversible twitch tension blockade and unaffected KCl- and ACh-evoked contractures, and the positive colabelling of acetylcholine receptors confirmed that their action was primarily at the motor nerve terminal. Hypercontraction and loose myofilaments and synaptic vesicle depletion and motor nerve damage indicated that the toxins displayed both myotoxic and neurotoxic effect. The blockade resulted from interference on synaptophysin, synaptobrevin, and SNAP25 proteins leading to the conclusion that BmjeTX-I and BmjeTX-II affected neurotransmitter release machinery by preventing the docking of synaptic vesicles to the axolemma of the nerve terminal. PMID:27635261

  4. Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom.

    PubMed

    Lisboa, Antonio; Melaré, Rodolfo; Franco, Junia R B; Bis, Carolina V; Gracia, Marta; Ponce-Soto, Luis A; Marangoni, Sérgio; Rodrigues-Simioni, Léa; da Cruz-Höfling, Maria Alice; Rocha, Thalita

    2016-01-01

    Neuromuscular preparations exposed to B. marajoensis venom show increases in the frequency of miniature end-plate potentials and twitch tension facilitation followed by presynaptic neuromuscular paralysis, without evidences of muscle damage. Considering that presynaptic toxins interfere into the machinery involved in neurotransmitter release (synaptophysin, synaptobrevin, and SNAP25 proteins), the main objective of this communication is to analyze, by immunofluorescence and western blotting, the expression of the synaptic proteins, synaptophysin, synaptobrevin, and SNAP25 and by myography, light, and transmission electron microscopy the pathology of motor nerve terminals and skeletal muscle fibres of chick biventer cervicis preparations (CBC) exposed in vitro to BmjeTX-I and BmjeTX-II toxins from B. marajoensis venom. CBC incubated with toxins showed irreversible twitch tension blockade and unaffected KCl- and ACh-evoked contractures, and the positive colabelling of acetylcholine receptors confirmed that their action was primarily at the motor nerve terminal. Hypercontraction and loose myofilaments and synaptic vesicle depletion and motor nerve damage indicated that the toxins displayed both myotoxic and neurotoxic effect. The blockade resulted from interference on synaptophysin, synaptobrevin, and SNAP25 proteins leading to the conclusion that BmjeTX-I and BmjeTX-II affected neurotransmitter release machinery by preventing the docking of synaptic vesicles to the axolemma of the nerve terminal. PMID:27635261

  5. Aerospace medicine at Brooks AFB, TX: hail and farewell.

    PubMed

    Nunneley, Sarah A; Webb, James T

    2011-05-01

    With the impending termination of USAF operations at Brooks Air Force Base (AFB) in San Antonio, TX, it is time to consider its historic role in Aerospace Medicine. The base was established in 1917 as a flight training center for the U.S. Army Air Service and in 1926 became home to its School of Aviation Medicine. The school moved to San Antonio's Randolph Field in 1931, but in 1959 it returned to Brooks where it occupied new facilities to support its role as a national center for U.S. Air Force aerospace medicine, including teaching, clinical medicine, and research. The mission was then expanded to encompass support of U.S. military and civilian space programs. With the abrupt termination of the military space program in 1969, research at Brooks focused on clinical aviation medicine and support of advanced military aircraft while continuing close cooperation with NASA in support of orbital spaceflight and the journey to the Moon. Reorganization in the 1990s assigned all research functions at Brooks to the Human Systems Division and its successors, leaving to USAFSAM the missions related to clinical work and teaching. In 2002 the USAF and the city of San Antonio implemented shared operation of Brooks as a "City-Base" in the hope of deflecting threatened closure. Nevertheless, under continuing pressure to consolidate military facilities in the United States, the 2005 Base Closure and Realignment Commission ordered Brooks closed by 2011, with its aerospace medicine functions relocated to new facilities at Wright-Patterson AFB in Dayton, OH.

  6. RCRA Assessment Plan for Single-Shell Tank Waste Management Area TX-TY

    SciTech Connect

    Horton, Duane G.

    2007-03-26

    WMA TX-TY contains underground, single-shell tanks that were used to store liquid waste that contained chemicals and radionuclides. Most of the liquid has been removed, and the remaining waste is regulated under the RCRA as modi¬fied in 40 CFR Part 265, Subpart F and Washington State’s Hazardous Waste Management Act . WMA TX-TY was placed in assessment monitoring in 1993 because of elevated specific conductance. A groundwater quality assessment plan was written in 1993 describing the monitoring activities to be used in deciding whether WMA TX-TY had affected groundwater. That plan was updated in 2001 for continued RCRA groundwater quality assessment as required by 40 CFR 265.93 (d)(7). This document further updates the assessment plan for WMA TX-TY by including (1) information obtained from ten new wells installed at the WMA after 1999 and (2) information from routine quarterly groundwater monitoring during the last five years. Also, this plan describes activities for continuing the groundwater assessment at WMA TX TY.

  7. Capacitance of Ti3C2Tx MXene in ionic liquid electrolyte

    NASA Astrophysics Data System (ADS)

    Lin, Zifeng; Barbara, Daffos; Taberna, Pierre-Louis; Van Aken, Katherine L.; Anasori, Babak; Gogotsi, Yury; Simon, Patrice

    2016-09-01

    Ti3C2Tx MXene, a two-dimensional (2D) early transition metal carbide, has shown an extremely high volumetric capacitance in aqueous electrolytes, but in a narrow voltage window (less than 1.23 V). The utilization of MXene materials in ionic liquid electrolytes with a large voltage window has never been addressed. Here, we report the preparation of the Ti3C2Tx MXene ionogel film by vacuum filtration for use as supercapacitor electrodes operating in 1-Ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMI-TFSI) neat ionic liquid electrolyte. Due to the disordered structure of the Ti3C2Tx hydrogel film and a stable spacing after vacuum drying, achieved through ionic liquid electrolyte immersion of the Ti3C2Tx hydrogel film, the Ti3C2Tx surface became accessible to EMI+ and TFSI- ions. A capacitance of 70 F g-1 together with a large voltage window of 3 V was obtained at a scan rate of 20 mV s-1 in neat EMI-TFSI electrolyte. The electrochemical signature indicates a capacitive behavior even at a high scan rate (500 mV s-1) and a high power performance. This work opens up the possibilities of using MXene materials with various ionic liquid electrolytes.

  8. LyeTx I, a potent antimicrobial peptide from the venom of the spider Lycosa erythrognatha.

    PubMed

    Santos, D M; Verly, R M; Piló-Veloso, D; de Maria, M; de Carvalho, M A R; Cisalpino, P S; Soares, B M; Diniz, C G; Farias, L M; Moreira, D F F; Frézard, F; Bemquerer, M P; Pimenta, A M C; de Lima, M E

    2010-06-01

    LyeTx I, an antimicrobial peptide isolated from the venom of Lycosa erythrognatha, known as wolf spider, has been synthesised and its structural profile studied by using the CD and NMR techniques. LyeTx I has shown to be active against bacteria (Escherichia coli and Staphylococcus aureus) and fungi (Candida krusei and Cryptococcus neoformans) and able to alter the permeabilisation of L: -alpha-phosphatidylcholine-liposomes (POPC) in a dose-dependent manner. In POPC containing cholesterol or ergosterol, permeabilisation has either decreased about five times or remained unchanged, respectively. These results, along with the observed low haemolytic activity, indicated that antimicrobial membranes, rather than vertebrate membranes seem to be the preferential targets. However, the complexity of biological membranes compared to liposomes must be taken in account. Besides, other membrane components, such as proteins and even specific lipids, cannot be discarded to be important to the preferential action of the LyeTx I to the tested microorganisms. The secondary structure of LyeTx I shows a small random-coil region at the N-terminus followed by an alpha-helix that reached the amidated C-terminus, which might favour the peptide-membrane interaction. The high activity against bacteria together with the moderate activity against fungi and the low haemolytic activity have indicated LyeTx I as a good prototype for developing new antibiotic peptides.

  9. Hanford Tank Farms Vadose Zone, Addendum to the TX Tank Farm Report

    SciTech Connect

    Spatz, R.

    2000-08-01

    This addendum to the TX Tank Farm Report (GJO-97-13-TAR, GJO-HAN-11) published in September 1997 incorporates the results of high-rate and repeat logging activities along with shape factor analysis of the logging data. A high-rate logging system was developed and deployed in the TX Tank Farm to measure cesium-137 concentration levels in high gamma flux zones where the spectral gamma logging system was unable to collect usable data because of high dead times and detector saturation. This report presents additional data and revised visualizations of subsurface contaminant distribution in the TX Tank Farm at the DOE Hanford Site in the state of Washington.

  10. Inhibitory effect of the recombinant Phoneutria nigriventer Tx1 toxin on voltage-gated sodium channels.

    PubMed

    Silva, Anita O; Peigneur, Steve; Diniz, Marcelo R V; Tytgat, Jan; Beirão, Paulo S L

    2012-12-01

    Phoneutria nigriventer toxin Tx1 (PnTx1, also referred to in the literature as Tx1) exerts inhibitory effect on neuronal (Na(V)1.2) sodium channels in a way dependent on the holding potential, and competes with μ-conotoxins but not with tetrodotoxin for their binding sites. In the present study we investigated the electrophysiological properties of the recombinant toxin (rPnTx1), which has the complete amino acid sequence of the natural toxin with 3 additional residues: AM on the N-terminal and G on the C-terminal. At the concentration of 1.5 μM, the recombinant toxin inhibits Na(+) currents of dorsal root ganglia neurons (38.4 ± 6.1% inhibition at -80 mV holding potential) and tetrodotoxin-resistant Na(+) currents (26.2 ± 4.9% at the same holding potential). At -50 mV holding potential the inhibition of the total current reached 71.3 ± 2.3% with 1.5 μM rPnTx1. The selectivity of rPnTx1 was investigated on ten different isoforms of voltage-gated sodium channels expressed in Xenopus oocytes. The order of potency for rPnTx1 was: rNa(V)1.2 > rNa(V)1.7 ≈ rNa(V)1.4 ≥ rNa(V)1.3 > mNa(V)1.6 ≥ hNa(V)1.8. No effect was seen on hNa(V)1.5 and on the arthropods isoforms (DmNa(V)1, BGNa(V)1.1a and VdNa(V)1). The IC(50) for Na(V)1.2 was 33.7 ± 2.9 nM with a maximum inhibition of 83.3 ± 1.9%. The toxin did not alter the voltage-dependence of channel gating and was effective on Na(V)1.2 channels devoid of inactivation. It was ineffective on neuronal calcium channels. We conclude that rPnTx1 has a promising selectivity, and that it may be a valuable model to achieve pharmacological activities of interest for the treatment of channelopathies and neuropathic pain. PMID:22968173

  11. Tank 241-TX-118 vapor sampling and analysis tank characterization report

    SciTech Connect

    Huckaby, J.L.

    1995-05-31

    Tank 241-TX-118 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in {open_quotes}Program Plan for the Resolution of Tank Vapor Issues.{close_quotes} Tank 241-TX-118 was vapor sampled in accordance with {open_quotes}Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.{close_quotes}

  12. Tank 241-TX-105 vapor sampling and analysis tank characterization report

    SciTech Connect

    Huckaby, J.L.

    1995-05-31

    Tank 241-TX-105 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in {open_quotes}Program Plan for the Resolution of Tank Vapor Issues.{close_quotes} Tank 241-TX-105 was vapor sampled in accordance with {open_quotes}Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.{close_quotes}

  13. A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities.

    PubMed

    Kuhn-Nentwig, Lucia; Fedorova, Irina M; Lüscher, Benjamin P; Kopp, Lukas S; Trachsel, Christian; Schaller, Johann; Vu, Xuan Lan; Seebeck, Thomas; Streitberger, Kathrin; Nentwig, Wolfgang; Sigel, Erwin; Magazanik, Lev G

    2012-07-20

    CsTx-1, the main neurotoxic acting peptide in the venom of the spider Cupiennius salei, is composed of 74 amino acid residues, exhibits an inhibitory cysteine knot motif, and is further characterized by its highly cationic charged C terminus. Venom gland cDNA library analysis predicted a prepropeptide structure for CsTx-1 precursor. In the presence of trifluoroethanol, CsTx-1 and the long C-terminal part alone (CT1-long; Gly-45-Lys-74) exhibit an α-helical structure, as determined by CD measurements. CsTx-1 and CT1-long are insecticidal toward Drosophila flies and destroys Escherichia coli SBS 363 cells. CsTx-1 causes a stable and irreversible depolarization of insect larvae muscle cells and frog neuromuscular preparations, which seem to be receptor-independent. Furthermore, this membranolytic activity could be measured for Xenopus oocytes, in which CsTx-1 and CT1-long increase ion permeability non-specifically. These results support our assumption that the membranolytic activities of CsTx-1 are caused by its C-terminal tail, CT1-long. Together, CsTx-1 exhibits two different functions; as a neurotoxin it inhibits L-type Ca(2+) channels, and as a membranolytic peptide it destroys a variety of prokaryotic and eukaryotic cell membranes. Such a dualism is discussed as an important new mechanism for the evolution of spider venomous peptides.

  14. rBmαTX14 Increases the Life Span and Promotes the Locomotion of Caenorhabditis Elegans.

    PubMed

    Chen, Lan; Zhang, Ju; Xu, Jie; Wan, Lu; Teng, Kaixuan; Xiang, Jin; Zhang, Rui; Huang, Zebo; Liu, Yongmei; Li, Wenhua; Liu, Xin

    2016-01-01

    The scorpion has been extensively used in various pharmacological profiles or as food supplies. The exploration of scorpion venom has been reported due to the presence of recombinant peptides. rBmαTX14 is an α-neurotoxin extracted from the venom gland of the East Asian scorpion Buthus martensii Karsch and can affect ion channel conductance. Here, we investigated the functions of rBmαTX14 using the Caenorhabditis elegans model. Using western blot analysis, rBmαTX14 was shown to be expressed both in the cytoplasm and inclusion bodies in the E.coli Rosetta (DE3) strain. Circular dichroism spectroscopy analysis demonstrated that purified rBmαTX14 retained its biological structures. Next, feeding nematodes with E.coli Rosetta (DE3) expressing rBmαTX14 caused extension of the life span and promoted the locomotion of the nematodes. In addition, we identified several genes that play various roles in the life span and locomotion of C. elegans through microarray analysis and quantitative real-time PCR. Furthermore, if the amino acid site H15 of rBmαTX14 was mutated, rBmαTX14 no longer promoted the C. elegans life span. In conclusion, the results not only demonstrated the functions and mechanism of rBmαTX14 in C. elegans, but also provided the new sight in the utility of recombinant peptides from scorpion venom. PMID:27611314

  15. 78 FR 9907 - TGP Development Company, LLC; TGP Flying Cloud Holdings, LLC; WEC TX Company, LLC v. Arizona...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission TGP Development Company, LLC; TGP Flying Cloud Holdings, LLC; WEC TX Company... Development Company, LLC, TGP Flying Cloud Holdings, LLC, and WEC TX Company, LLC (collectively,...

  16. rBmαTX14 Increases the Life Span and Promotes the Locomotion of Caenorhabditis Elegans

    PubMed Central

    Xu, Jie; Wan, Lu; Teng, Kaixuan; Xiang, Jin; Zhang, Rui; Huang, Zebo; Liu, Yongmei; Li, Wenhua; Liu, Xin

    2016-01-01

    The scorpion has been extensively used in various pharmacological profiles or as food supplies. The exploration of scorpion venom has been reported due to the presence of recombinant peptides. rBmαTX14 is an α-neurotoxin extracted from the venom gland of the East Asian scorpion Buthus martensii Karsch and can affect ion channel conductance. Here, we investigated the functions of rBmαTX14 using the Caenorhabditis elegans model. Using western blot analysis, rBmαTX14 was shown to be expressed both in the cytoplasm and inclusion bodies in the E.coli Rosetta (DE3) strain. Circular dichroism spectroscopy analysis demonstrated that purified rBmαTX14 retained its biological structures. Next, feeding nematodes with E.coli Rosetta (DE3) expressing rBmαTX14 caused extension of the life span and promoted the locomotion of the nematodes. In addition, we identified several genes that play various roles in the life span and locomotion of C. elegans through microarray analysis and quantitative real-time PCR. Furthermore, if the amino acid site H15 of rBmαTX14 was mutated, rBmαTX14 no longer promoted the C. elegans life span. In conclusion, the results not only demonstrated the functions and mechanism of rBmαTX14 in C. elegans, but also provided the new sight in the utility of recombinant peptides from scorpion venom. PMID:27611314

  17. 33 CFR 165.819 - Security Zone; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Sabine-Neches Waterway, TX. (a) Location. (1) The following LNG facility mooring basins are designated as fixed security zones whenever LNG carriers are moored within them: (i) Golden Pass LNG, Sabine TX: All...°45′50″ N, 093°55′17″ W. (ii) Sabine Pass LNG, Cameron Parish, LA: All mooring basin waters north of...

  18. 33 CFR 165.819 - Security Zone; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Sabine-Neches Waterway, TX. (a) Location. (1) The following LNG facility mooring basins are designated as fixed security zones whenever LNG carriers are moored within them: (i) Golden Pass LNG, Sabine TX: All...°45′50″ N, 093°55′17″ W. (ii) Sabine Pass LNG, Cameron Parish, LA: All mooring basin waters north of...

  19. 78 FR 33015 - Proposed Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco, TSTC-Waco Airport, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to amend Class...

  20. Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins.

    PubMed

    Pimentel, Cyril; M'Barek, Sarrah; Visan, Violetta; Grissmer, Stephan; Sampieri, François; Sabatier, Jean-Marc; Darbon, Hervé; Fajloun, Ziad

    2008-01-01

    Agitoxin 2 (AgTx2) is a 38-residue scorpion toxin, cross-linked by three disulfide bridges, which acts on voltage-gated K(+) (Kv) channels. Maurotoxin (MTX) is a 34-residue scorpion toxin with an uncommon four-disulfide bridge reticulation, acting on both Ca(2+)-activated and Kv channels. A 39-mer chimeric peptide, named AgTx2-MTX, was designed from the sequence of the two toxins and chemically synthesized. It encompasses residues 1-5 of AgTx2, followed by the complete sequence of MTX. As established by enzyme cleavage, the new AgTx2-MTX molecule displays half-cystine pairings of the type C1-C5, C2-C6, C3-C7, and C4-C8, which is different from that of MTX. The 3D structure of AgTx2-MTX solved by (1)H-NMR, revealed both alpha-helical and beta-sheet structures, consistent with a common alpha/beta scaffold of scorpion toxins. Pharmacological assays of AgTx2-MTX revealed that this new molecule is more potent than both original toxins in blocking rat Kv1.2 channel. Docking simulations, performed with the 3D structure of AgTx2-MTX, confirmed this result and demonstrated the participation of the N-terminal domain of AgTx2 in its increased affinity for Kv1.2 through additional molecular contacts. Altogether, the data indicated that replacement of the N-terminal domain of MTX by the one of AgTx2 in the AgTx2-MTX chimera results in a reorganization of the disulfide bridge arrangement and an increase of affinity to the Kv1.2 channel.

  1. Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins

    PubMed Central

    Pimentel, Cyril; M'Barek, Sarrah; Visan, Violetta; Grissmer, Stephan; Sampieri, François; Sabatier, Jean-Marc; Darbon, Hervé; Fajloun, Ziad

    2008-01-01

    Agitoxin 2 (AgTx2) is a 38-residue scorpion toxin, cross-linked by three disulfide bridges, which acts on voltage-gated K+ (Kv) channels. Maurotoxin (MTX) is a 34-residue scorpion toxin with an uncommon four-disulfide bridge reticulation, acting on both Ca2+-activated and Kv channels. A 39-mer chimeric peptide, named AgTx2-MTX, was designed from the sequence of the two toxins and chemically synthesized. It encompasses residues 1–5 of AgTx2, followed by the complete sequence of MTX. As established by enzyme cleavage, the new AgTx2-MTX molecule displays half-cystine pairings of the type C1–C5, C2–C6, C3–C7, and C4–C8, which is different from that of MTX. The 3D structure of AgTx2-MTX solved by 1H-NMR, revealed both α-helical and β-sheet structures, consistent with a common α/β scaffold of scorpion toxins. Pharmacological assays of AgTx2-MTX revealed that this new molecule is more potent than both original toxins in blocking rat Kv1.2 channel. Docking simulations, performed with the 3D structure of AgTx2-MTX, confirmed this result and demonstrated the participation of the N-terminal domain of AgTx2 in its increased affinity for Kv1.2 through additional molecular contacts. Altogether, the data indicated that replacement of the N-terminal domain of MTX by the one of AgTx2 in the AgTx2-MTX chimera results in a reorganization of the disulfide bridge arrangement and an increase of affinity to the Kv1.2 channel. PMID:18042681

  2. Daytime HONO vertical gradients during SHARP 2009 in Houston, TX

    NASA Astrophysics Data System (ADS)

    Wong, K. W.; Tsai, C.; Lefer, B.; Haman, C.; Grossberg, N.; Brune, W. H.; Ren, X.; Luke, W.; Stutz, J.

    2012-01-01

    Nitrous Acid (HONO) plays an important role in tropospheric chemistry as a precursor of the hydroxyl radical (OH), the most important oxidizing agent in the atmosphere. Nevertheless, the formation mechanisms of HONO are still not completely understood. Recent field observations found unexpectedly high daytime HONO concentrations in both urban and rural areas, which point to unrecognized, most likely photolytically enhanced HONO sources. Several gas-phase, aerosol, and ground surface chemistry mechanisms have been proposed to explain elevated daytime HONO, but atmospheric evidence to favor one over the others is still weak. New information on whether HONO formation occurs in the gas-phase, on aerosol, or at the ground may be derived from observations of the vertical distribution of HONO and its precursor nitrogen dioxide, NO2, as well as from its dependence on solar irradiance or actinic flux. Here we present field observations of HONO, NO2 and other trace gases in three altitude intervals (30-70 m, 70-130 m and 130-300 m) using UCLA's long path DOAS instrument, as well as in situ measurements of OH, NO, photolysis frequencies and solar irradiance, made in Houston, TX, during the Study of Houston Atmospheric Radical Precursor (SHARP) experiment from 20 April to 30 May 2009. The observed HONO mixing ratios were often ten times larger than the expected photostationary state with OH and NO. Larger HONO mixing ratios observed near the ground than aloft imply, but do not clearly prove, that the daytime source of HONO was located at or near the ground. Using a pseudo steady-state (PSS) approach, we calculated the missing daytime HONO formation rates, Punknown, on four sunny days. The NO2-normalized Punknown, Pnorm, showed a clear symmetrical diurnal variation with a maximum around noontime, which was well correlated with actinic flux (NO2 photolysis frequency) and solar irradiance. This behavior, which was found on all clear days in Houston, is a strong indication of a

  3. 76 FR 49285 - Amendment of Class D Airspace; Corpus Christi, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... Cabaniss NOLF, Corpus Christi, TX (76 FR 31821, Docket No. FAA-2010-1171). Subsequent to publication, an... published in the Federal Register June 2, 2010 (76 FR 31821), (FR Doc. 2011-13559), are corrected as follows... the geographic coordinates in the regulatory text of a final rule that was published in the...

  4. 76 FR 31821 - Amendment of Class D Airspace; Corpus Christi, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... Executive Order 12866; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR...), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The... amends Class D airspace within the Corpus Christi, TX, area by updating the geographic coordinates...

  5. 78 FR 74008 - Amendment of Class E Airspace; Del Rio, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ... Del Rio, TX, area, creating additional controlled airspace at Laughlin AFB (78 FR 52716) Docket No... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. ] Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  6. 76 FR 15857 - Radio Broadcasting Services; Early and Lake Brownwood, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Early and Lake Brownwood, TX AGENCY: Federal... the Congressional Review Act, see U.S.C. 801(a)(1)(A). List Of Subjects in 47 CFR Part 73 Radio, Radio... CFR part 73 as follows: PART 73--RADIO BROADCAST SERVICES 0 1. The authority citation for Part...

  7. 77 FR 66743 - Radio Broadcasting Services; Crowell, Knox City, Quanah, and Rule, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ... MM Docket No. 00-148 are considered final. See Quanah, Texas, et al, 76 FR 42573, published July 19... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Crowell, Knox City, Quanah, and Rule, TX AGENCY... in 47 CFR Part 73 Radio, Radio broadcasting. Federal Communications Commission. Nazifa...

  8. 77 FR 60103 - Approval of Subzone Status; TST NA TRIM, LLC; Hidalgo, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ... (77 FR 47816, 08/10/2012). The FTZ staff examiner reviewed the application and determined that it... Foreign-Trade Zones Board Approval of Subzone Status; TST NA TRIM, LLC; Hidalgo, TX On August 3, 2012, the... limit of FTZ 12, on behalf of TST NA TRIM, LLC, in Hidalgo, Texas. The application was processed...

  9. Ti3C2Tx Filler Effect on the Proton Conduction Property of Polymer Electrolyte Membrane.

    PubMed

    Liu, Yahua; Zhang, Jiakui; Zhang, Xiang; Li, Yifan; Wang, Jingtao

    2016-08-10

    Conductive polymer electrolyte membranes are increasingly attractive for a wide range of applications in hydrogen-relevant devices, for instance hydrogen fuel cells. In this study, two-dimensional Ti3C2Tx, a typical representative of the recently developed MXene family, is synthesized and employed as a universal filler for its features of large specific surface area, high aspect ratio, and sufficient terminated -OH groups. The Ti3C2Tx is incorporated into polymer matrix to explore its function on membrane microstructure and proton conduction property. Both phase-separated (acidic Nafion and sulfonated poly(ether ether ketone)) and non-phase-separated (basic chitosan) polymers are utilized as membrane matrixes. The microstructures, physicochemical properties, and proton conduction properties of the membranes are extensively investigated. It is demonstrated that Ti3C2Tx generates significant promotion effect on proton conduction of the composite membrane by facilitating both vehicle-type and Grotthuss-type proton transfer, yielding several times increased proton conductivity for every polymer-based composite membrane under various conditions, and the composite membrane achieves elevated hydrogen fuel cell performance. The stable Ti3C2Tx also reinforces the thermal and mechanical stabilities of these composite membranes. Since the MXene family includes more than 70 members, this exploration is expected to open up new perspectives for expanding their applications, especially as membrane modifiers and proton conductors. PMID:27430190

  10. 76 FR 53352 - Proposed Amendment of Class E Airspace; Alice, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... continues to read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... instrument approach procedures at Old Hoppe Place Airport, Agua Dulce, TX, has made this action necessary...

  11. 76 FR 5303 - Proposed Amendment of Class E Airspace; Carrizo Springs, Glass Ranch Airport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The..., Glass Ranch Airport, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of...

  12. 76 FR 318 - Designation for the Columbus, OH; Dallas, TX; and Decatur, IN Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ...)). SUPPLEMENTARY INFORMATION: In the May 25, 2010, Federal Register (75 FR 29310), GIPSA requested applications for... Grain Inspection, Packers and Stockyards Administration Designation for the Columbus, OH; Dallas, TX; and Decatur, IN Areas AGENCY: Grain Inspection, Packers and Stockyards Administration, USDA....

  13. 75 FR 6319 - Proposed Amendment of Low Altitude Area Navigation Route T-254; Houston, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ...) Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... continues to read as follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3... altitude Area Navigation (RNAV) route T-254 in the Houston, TX, terminal area by eliminating the...

  14. 78 FR 26799 - Waterway Suitability Assessment for Expansion of Liquefied Gas Terminals; Beaumont, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... the January 17, 2008, issue of the Federal Register (73 FR 3316). Public meeting: We do not now plan... SECURITY Coast Guard Waterway Suitability Assessment for Expansion of Liquefied Gas Terminals; Beaumont, TX... construction to expand or modify marine terminal operations in an existing facility handling Liquefied...

  15. 75 FR 81442 - Revocation of Class E Airspace; Lone Star, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... rulemaking to remove Class E airspace for Lone Star, TX. (75 FR 64972) Docket No. FAA-2010-0772. Interested...) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26..., 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  16. 33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Regulated Navigation Area; Galveston Channel, TX. 165.827 Section 165.827 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED...

  17. 33 CFR 165.827 - Regulated Navigation Area; Galveston Channel, TX.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Regulated Navigation Area; Galveston Channel, TX. 165.827 Section 165.827 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION AREAS AND LIMITED...

  18. Ti3C2Tx Filler Effect on the Proton Conduction Property of Polymer Electrolyte Membrane.

    PubMed

    Liu, Yahua; Zhang, Jiakui; Zhang, Xiang; Li, Yifan; Wang, Jingtao

    2016-08-10

    Conductive polymer electrolyte membranes are increasingly attractive for a wide range of applications in hydrogen-relevant devices, for instance hydrogen fuel cells. In this study, two-dimensional Ti3C2Tx, a typical representative of the recently developed MXene family, is synthesized and employed as a universal filler for its features of large specific surface area, high aspect ratio, and sufficient terminated -OH groups. The Ti3C2Tx is incorporated into polymer matrix to explore its function on membrane microstructure and proton conduction property. Both phase-separated (acidic Nafion and sulfonated poly(ether ether ketone)) and non-phase-separated (basic chitosan) polymers are utilized as membrane matrixes. The microstructures, physicochemical properties, and proton conduction properties of the membranes are extensively investigated. It is demonstrated that Ti3C2Tx generates significant promotion effect on proton conduction of the composite membrane by facilitating both vehicle-type and Grotthuss-type proton transfer, yielding several times increased proton conductivity for every polymer-based composite membrane under various conditions, and the composite membrane achieves elevated hydrogen fuel cell performance. The stable Ti3C2Tx also reinforces the thermal and mechanical stabilities of these composite membranes. Since the MXene family includes more than 70 members, this exploration is expected to open up new perspectives for expanding their applications, especially as membrane modifiers and proton conductors.

  19. 78 FR 54795 - Proposed Amendment of Class D Airspace; Dallas, Addison Airport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-06

    ... to air traffic flows in the Dallas-Fort Worth metropolitan area has made it necessary to lower the... 71 by amending Class D airspace at Addison Airport, Dallas, TX. Adjustments to air traffic flows in... accessed through the FAA's Web page at...

  20. 75 FR 66013 - Proposed Amendment of Class E Airspace; Horseshoe Bay, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Bay Resort non-directional beacon (NDB) at Horseshoe Bay Resort Airport, Horseshoe Bay, TX, has...

  1. 78 FR 19097 - Establishment of Class E Airspace; Round Mountain, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... the West Ranch Airport, Round Mountain, TX (77 FR 71367) Docket No. FAA-2012-0771. Interested parties... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  2. 77 FR 71367 - Proposed Establishment of Class E Airspace; Round Mountain, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February.... 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 2. The... Mountain, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

  3. 76 FR 14052 - Notice of Inventory Completion: Sabine River Authority of Texas, Quitman, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... Texas, Denton, TX, for forensic evaluation. The human remains and non-human bone fragments, which are... 6, 2006. No known individual was identified. The 20 associated funerary objects are non-human bone fragments. Dr. Harrell Gill-King, Anthropologist, University of North Texas, performed an examination of...

  4. 76 FR 13083 - Amendment to VOR Federal Airway V-358; TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... Federal Register amending thirteen Federal airways in the vicinity of Dallas/ Fort Worth, TX (65 FR 61087... (66 FR 50101). The realignment around P-49 was necessary to assist the United States Secret Service in... in the Federal Register amending the V-358 airway description (74 FR 54896). That rule renamed...

  5. 76 FR 30396 - Deloitte Financial Advisory Services LLP, Real Estate Consulting, Houston, TX; Amended...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Deloitte Financial Advisory Services LLP, Real Estate Consulting, Houston, TX; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of the Trade Act...

  6. 75 FR 17851 - Amendment of Class E Airspace; Dallas-Fort Worth, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ... proposed rulemaking to amend Class E airspace for the Dallas- Fort Worth, TX area (74 FR 57617) Docket No... Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of... follows: Authority: 49 U.S.C. 106(g), 40103, 40113, 40120; E. O. 10854, 24 FR 9565, 3 CFR, 1959-1963...

  7. Encounters with Wisdom: A Case Study of Community Worker Reflection Circles in San Antonio, TX

    ERIC Educational Resources Information Center

    Arispe, Don D.

    2013-01-01

    This case study focuses upon the transformational experiences of 28 social service and pastoral workers engaged in a Reflection Circle Process (RCP) in San Antonio, TX. The RCP involves the writing of a holistic journal entry, known as a process note, coupled with an in-depth exploration of the note with the help of a group of trusted peers, known…

  8. Preliminary tank characterization report for single-shell tank 241-TX-116: best-basis inventory

    SciTech Connect

    Place, D.E.

    1997-06-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-116 was performed, and a bost-basis inventory was established. This work follows the methodology that was established by the standard inventory task.

  9. Preliminary tank characterization report for single-shell tank 241-TX-117: best-basis inventory

    SciTech Connect

    Place, D.E.

    1997-06-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-117 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task.

  10. 78 FR 48293 - Amendment of Class D and Class E Airspace; San Marcos, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... new Area Navigation (RNAV) Standard Instrument Approach Procedures at San Marcos Municipal Airport and... incorporation by reference action under 1 CFR Part 51, subject to the annual revision of FAA Order 7400.9 and... airspace for the San Marcos, TX, area, creating additional controlled airspace at San Marcos...

  11. 75 FR 12726 - Expansion/Reorganization of Foreign-Trade Zone 149; Port Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... comment has been given in the Federal Register (73 FR 78289, 12/22/2008 and 74 FR 42050, 8/20/2009) and... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion/Reorganization of Foreign-Trade Zone 149; Port Freeport, TX...

  12. 75 FR 15992 - Revision of Prohibited Area P-49; Crawford, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... that while the security requirements for establishing P-49 Crawford, TX (66 FR 16391) remain valid... ``significant rule'' under Department of Transportation (DOT) Regulatory Policies and Procedures (44 FR 11034...), 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 73.89 0 2. Sec....

  13. Fatty acids and TxA2 generation, in the absence of platelet-COX-1 activity

    PubMed Central

    DeFilippis, A.P.; Rai, S.N.; Cambon, A.; Miles, R.J.; Jaffe, A.S.; Moser, A.B.; Jones, R.O.; Bolli, R.; Schulman, S.P.

    2015-01-01

    Background and aims Omega-3 fatty acids suppress Thromboxane A2 (TxA2) generation via mechanisms independent to that of aspirin therapy. We sought to evaluate whether baseline omega-3 fatty acid levels influence arachidonic acid proven platelet-cyclooxygenase-1 (COX-1) independent TxA2 generation (TxA2 generation despite adequate aspirin use). Methods and results Subjects with acute myocardial infarction, stable CVD or at high risk for CVD, on adequate aspirin therapy were included in this study. Adequate aspirin action was defined as complete inhibition of platelet-COX-1 activity as assessed by <10% change in light transmission aggregometry to ≥1 mmol/L arachidonic acid. TxA2 production was measured via liquid chromatography–tandem mass spectrometry for the stable TxA2 metabolite 11-dehydro-thromboxane B2 (UTxB2) in urine. The relationship between baseline fatty acids, demographics and UTxB2 were evaluated. Baseline omega-3 fatty acid levels were not associated with UTxB2 concentration. However, smoking was associated with UTxB2 in this study. Conclusion Baseline omega-3 fatty acid levels do not influence TxA2 generation inpatients with or at high risk for CVD receiving adequate aspirin therapy. The association of smoking and TxA2 generation, in the absence of platelet COX-1 activity, among aspirin treated patients warrants further study. PMID:24370448

  14. Calcium-dependent contractile response of arterial smooth muscle to a jellyfish toxin (pCrTX: Carybdea rastonii).

    PubMed Central

    Azuma, H.; Ishikawa, M.; Nakajima, T.; Satoh, A.; Sekizaki, S.

    1986-01-01

    The purpose of the present experiments was to investigate the pharmacological mechanisms of the vasoconstriction caused by the toxin (pCrTX) which had been partially purified from the tentacles of the jellyfish Carybdea rastonii ('Andonkurage'). pCrTX (0.1 to 10 micrograms ml-1) produced a tonic contraction of rabbit aortic strips, which was nearly abolished in Ca2+-free medium and was significantly reduced by verapamil or diltiazem. pCrTX stimulated 45Ca2+-influx and this effect was markedly attenuated by verapamil. pCrTX-induced vasoconstriction was significantly attenuated by phentolamine, 6-hydroxydopamine (6-OHDA) and in low Na+-medium, but not by bretylium, guanethidine, reserpinization or tetrodotoxin (TTX). pCrTX continuously and significantly increased the 3H-efflux from [3H]-noradrenaline preloaded aortic strips and this effect was completely inhibited by pretreatment with 6-OHDA and in Ca2+-free medium, but not by phentolamine, bretylium, guanethidine or TTX. A single exposure to pCrTX for 30 min greatly reduced the contractile responses to tyramine, nicotine and transmural electrical stimulation, but not those to noradrenaline or KC1. In addition, incorporation of [3H]-noradrenaline was reduced. Pretreatments with chlorphenylamine or indomethacin failed to modify the contractile response to pCrTX. These results suggest that the pCrTX-induced vasoconstriction is caused by a presynaptic action, releasing noradrenaline from the intramural adrenergic nerve terminals, and by a postsynaptic action, which consists at least in part of stimulation of the transmembrane calcium influx. Both pre- and postsynaptic actions depend on the external calcium concentration. The data further suggest that pCrTX damages the noradrenaline uptake and/or storage mechanisms without damaging postsynaptic contractile systems. PMID:2874856

  15. 77 FR 22558 - Foreign-Trade Zone 155-Calhoun and Victoria Counties, TX; Application for Reorganization Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... authority to reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170- 1173, 01/12/09 (correction 74 FR 3987, 01/22/09); 75 FR 71069-71070, 11/22/10). The ASF is an option... FR 44510, 11/3/88), and expanded on June 18, 2008 (Board Order 1565, 73 FR 36038-36039, 6/25/08)....

  16. 75 FR 61706 - Reorganization of Foreign-Trade Zone 113 Under Alternative Site Framework; Ellis County, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... inviting public comment was given in the Federal Register (75 FR 3705, 01/22/10; 75 FR 17125, 04/05/10)...

  17. 77 FR 69789 - Foreign-Trade Zone 171-Liberty County, TX; Application for Reorganization/Expansion Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... January 4, 1991 (Board Order 501, 56 FR 1166, 1/1/91), and expanded on August 9, 1999 (Board Order 1049, 64 FR 46181, 8/24/99), on April 15, 2002 (Board Order 1225, 67 FR 20087, 4/24/02), and on July 22, 2004 (Board Order 1343, 69 FR 45673- 45674, 7/30/04). The current zone includes the following...

  18. Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two major myotoxins, BthTX-I and BthTX-II, by the aqueous extract of Tabernaemontana catharinensis A. DC. (Apocynaceae).

    PubMed

    Veronese, E L G; Esmeraldino, L E; Trombone, A P F; Santana, A E; Bechara, G H; Kettelhut, I; Cintra, A C O; Giglio, J R; Sampaio, S V

    2005-01-01

    Partial neutralization of the myotoxic effect of Bothrops jararacussu venom (BV) and two of its myotoxins [bothropstoxin-I (BthTX-I), catalytically inactive, and II (BthTX-II), showing low PLA2 activity], by the lyophilized aqueous extract of Tabernaemontana catharinensis (AE), was studied in rat isolated soleus muscle preparations (in vitro) and through i.m. injection in the gastrocnemius muscle (in vivo) by determination of creatine kinase (CK) activity and histopathological analysis. Incubation of soleus muscle for 1 h with BV or toxins (20 microg/ml) plus AE (400 microg/ml) added immediately after BV, BthTX-I or BthTX-II reduced CK levels by 53%, 37% and 56%, respectively. The myonecrotic effects of BV (20 microg/ml) upon soleus muscle was reduced 24%, 35% and 36% when AE (400 microg/ml) was added 1 h after BV and CK was evaluated 30 min, 1 and 2 h later, respectively. For BthTX-I these values were 46%, 48% and 47%, while for BthTX-II no inhibitory effect was detected. Histological analysis of soleus muscle after incubation with AE (400 microg/ml, 1 h) did not reveal any change in muscle fibers, but severe necrosis induced by BV or toxins (20 microg/ml) was clearly in evidence, and decreased significantly when soleus muscle was protected by AE. This protection was also observed when AE was administered 1 h after BV or BthTX-I, but not after BthTX-II. AE did not inhibit the catalytic PLA2 activity of BthTX-II or BV and did not change the PAGE pattern of BV, BthTX-I or BthTX-II. In vivo assays were performed in 100-g rats and maximal CK release was attained at a dose of 100 microg of BV, 3 h after injection. AE was not effective when injected 20 s after BV or toxins. However, injecting BV or toxins (100 microg), which were pre-incubated with AE (2 mg) caused an inhibition of 57%, 59% and 51%, respectively, with zero time pre-incubation, but was less effective with 1 h pre-incubation. This plant represents a potential source of promising myotoxin inhibitors.

  19. 77 FR 65360 - Foreign-Trade Zone 168-Dallas/Ft. Worth, TX; Notification of Proposed Production Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-26

    ... Production Activity, Richemont North America, Inc. dba Cartier (Eyewear Assembly/Kitting), Grand Prairie, TX...), located in Grand Prairie, Texas. The notification conforming to the requirements of the regulations of...

  20. 78 FR 4125 - Foreign-Trade Zone 265-Conroe, TX; Authorization of Production Activity; Bauer Manufacturing, Inc...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... notice in the Federal Register inviting public comment (77 FR 58354, 9-20-2012). The FTZ Board has... Manufacturing, Inc. (Pile Drivers and Boring Machinery), Conroe, TX On September 12, 2012, the City of...

  1. The cytotoxic mechanism of karlotoxin 2 (KmTx 2) from Karlodinium veneficum (Dinophyceae)

    PubMed Central

    Deeds, Jonathan R.; Hoesch, Robert E.; Place, Allen R.; Kao, Joseph P.Y.

    2015-01-01

    This study demonstrates that the polyketide toxin karlotoxin 2 (KmTx 2) produced by Karlodinium veneficum, a dinoflagellate associated with fish kills in temperate estuaries worldwide, alters vertebrate cell membrane permeability. Microfluorimetric and electrophysiological measurements were used to determine that vertebrate cellular toxicity occurs through non-selective permeabilization of plasma membranes, leading to osmotic cell lysis. Previous studies showed that KmTx 2 is lethal to fish at naturally-occurring concentrations measured during fish kills, while sub-lethal doses severely damage gill epithelia. This study provides a mechanistic explanation for the association between K. veneficum blooms and fish kills that has long been observed in temperate estuaries worldwide. PMID:25546005

  2. Disposal of hazardous materials from TxDOT activities. Final report, September 1992-August 1994

    SciTech Connect

    Stallard, M.; Corapcioglu, M.Y.; Beavers, T.; Beck, B.; Mehevec, A.

    1994-11-01

    The process of purchasing, storing, handling and disposal of hazardous waste is demanding. The Texas Department of Transportation deals with many such compounds every day in performing its duty of maintaining over 70,000 miles of Texas roadway. With the new demands being placed on all users of hazardous materials by the new EPA guidelines, procedures must be enacted to ensure TxDOT`s compliance with these ever-changing regulations. The placement of full-time safety and hazardous materials coordinators in each district office will help to ensure that employees follow reporting procedures and use disposal guidelines. The report will discuss these actions and others that might help TxDOT in this task.

  3. PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina

    PubMed Central

    Binda, Nancy Scardua; Porto Petruceli Carayon, Charles; Agostini, Rafael Mourão; do Nascimento Pinheiro, Ana Cristina; Nascimento Cordeiro, Marta; Romano Silva, Marco Aurélio; Figueira Silva, Juliana; Rita Pereira, Elizete Maria; da Silva Junior, Claudio Antonio; de Castro Junior, Célio José; Sena Guimarães, Andre Luiz; Gomez, Marcus Vinicius

    2016-01-01

    The in vivo neuroprotective effect of PhTx3-4, a spider toxin N-P/Q calcium channel blocker, was studied in a rat model of NMDA-induced injury of the retina. NMDA (N-Methyl-d-Aspartate)-induced retinal injury in rats reduced the b-wave amplitude by 62% ± 3.6%, indicating the severity of the insult. PhTx3-4 treatment increased the amplitude of the b-wave, which was almost equivalent to the control retinas that were not submitted to injury. The PhTx3-4 functional protection of the retinas recorded on the ERG also was observed in the neuroprotection of retinal cells. NMDA-induced injury reduced live cells in the retina layers and the highest reduction, 84%, was in the ganglion cell layer. Notably, PhTx3-4 treatment caused a remarkable reduction of dead cells in the retina layers, and the highest neuroprotective effect was in the ganglion cells layer. NMDA-induced cytotoxicity of the retina increased the release of glutamate, reactive oxygen species (ROS) production and oxidative stress. PhTx3-4 treatment reduced glutamate release, ROS production and oxidative stress measured by malondialdehyde. Thus, we presented for the first time evidence of in vivo neuroprotection from NMDA-induced retinal injury by PhTx3-4 (-ctenitoxin-Pn3a), a spider toxin that blocks N-P/Q calcium channels. PMID:26978403

  4. Optimal Cleavage and Oxidative Folding of α-Conotoxin TxIB as a Therapeutic Candidate Peptide

    PubMed Central

    Wu, Xiaosa; Wu, Yong; Zhu, Furong; Yang, Qiuyuan; Wu, Qianqian; Zhangsun, Dongting; Luo, Sulan

    2013-01-01

    Alpha6beta2 nicotinic acetylcholine receptors (nAChRs) are potential therapeutic targets for the treatment of several neuropsychiatric diseases, including addiction and Parkinson’s disease. Alpha-conotoxin (α-CTx) TxIB is a uniquely selective ligand, which blocks α6/α3β2β3 nAChRs only, but does not block the other subtypes. Therefore, α-CTx TxIB is a valuable therapeutic candidate peptide. Synthesizing enough α-CTx TxIB with high yield production is required for conducting wide-range testing of its potential medicinal applications. The current study optimized the cleavage of synthesized α-CTx TxIB resin-bounded peptide and folding of the cleaved linear peptide. Key parameters influencing cleavage and oxidative folding of α-CTx TxIB were examined, such as buffer, redox agents, pH, salt, co-solvent and temperature. Twelve conditions were used for cleavage optimization. Fifty-four kinds of one-step oxidative solution were used to assess their effects on each α-CTx TxIB isomers’ yield. The result indicated that co-solvent choices were particularly important. Completely oxidative folding of globular isomer was achieved when the NH4HCO3 or Tris-HCl folding buffer at 4 °C contained 40% of co-solvent DMSO, and GSH:GSSG (2:1) or GSH only with pH 8~8.7. PMID:24048271

  5. Recombinant conotoxin, TxVIA, produced in yeast has insecticidal activity.

    PubMed

    Bruce, C; Fitches, E C; Chougule, N; Bell, H A; Gatehouse, J A

    2011-07-01

    Conotoxins are a diverse collection of more than 50,000 peptides produced by predatory marine snails of the genus Conus in order to immobilize their prey. Many conotoxins modulate the activity of ion channels, and show high specificity to their targets; as a result, some have valuable pharmaceutical applications. However, obtaining active peptide is difficult and to date has only been achieved though natural collection, chemical synthesis, or the use of prokaryotic expression systems, which often have the disadvantage of requiring subsequent steps to correctly fold the peptide. This paper reports the production of a conotoxin, TxVIA from Conus textile, as a biologically active recombinant protein, using the yeast Pichia pastoris as expression host. The presence of the pro-peptide was found to be necessary for the expression of biologically active conotoxin. We also show that TxVIA is not, as previously reported, mollusc-specific, but also shows insecticidal activity when injected into lepidopteran (cabbage moth) and dipteran (house fly) larvae. In contrast, recombinant TxVIA was not found to be molluscicidal to the grey field slug Deroceras reticulatum. PMID:21640131

  6. Enhanced soil washing of phenanthrene by mixed solutions of TX100 and SDBS.

    PubMed

    Yang, Kun; Zhu, Lizhong; Xing, Baoshan

    2006-07-01

    Increased desorption of hydrophobic organic compounds (HOCs) from soils and sediments is a key to the remediation of contaminated soils and groundwater. In this study, phenanthrene desorption from a contaminated soil by mixed solutions of a nonionic surfactant(octylphenol polyethoxylate, TX100) and an anionic surfactant (sodium dodecylbenzenesulfonate, SDBS) was investigated. Phenanthrene desorption depended on not only aqueous surfactant concentrations and phenanthrene solubility enhancement but also the soil-sorbed surfactant amount and the corresponding sorption capacity of sorbed surfactants. The added surfactant critical desorption concentrations (CDCs) for phenanthrene from soil depended on both sorbed concentrations of surfactants and their critical micelle concentrations (CMCs). Phenanthrene desorption by mixed solutions was more efficient than individual surfactants due to the low sorption loss of mixed surfactants to soil. Among the tested surfactant systems, mixed TX100 and SDBS with a 1:9 mass ratio exhibited the highest phenanthrene desorption. Mixed micelle formation, showing negative deviation of CMCs from the ones predicted by the ideal mixing theory, was primarily responsible for the significant reduction of soil-sorbed amounts of TX100 and SDBS in their mixed systems. Therefore, mixed anionic-nonionic surfactants had great potential in the area of enhanced soil and groundwater remediation.

  7. Effects of deletion and insertion of amino acids on the activity of HelaTx1, a scorpion toxin on potassium channels.

    PubMed

    Peigneur, Steve; Esaki, Nao; Yamaguchi, Yoko; Tytgat, Jan; Sato, Kazuki

    2016-03-01

    Four analogs of HelaTx1, a 25-mer peptide from scorpion venom, were synthesized by deleting its C-terminal hexapeptide fragment and N-terminal Ser residue and by inserting an amino acid in the middle part of the molecule. CD spectrum of HelaTx1(1-19) was almost superimposable to that of native HelaTx1. Functional characterization showed that HelaTx1(1-19) retained its inhibitory activity on Kv1.1 channel although 3 times less potent than HelaTx1, indicating that C-terminal part of HelaTx1 was not essential for its conformation and activity. Further deletion of N-terminal Ser residue and insertion of Ala in the middle part of the molecule affected the CD spectra and resulted in the decrease of activity.

  8. County Staff or Area Staff?

    ERIC Educational Resources Information Center

    McIntyre, William J.

    1970-01-01

    McIntryre explores the questions of county-based extention and increased specialization in Indiana. He compares the multi-county with individual county systems using variables including clientele's reactions to the two systems. (NL)

  9. Vapor space characterization of waste Tank 241-TX-118 (in situ): Results from samples collected on 9/7/94

    SciTech Connect

    Thomas, B.L.; Clauss, T.W.; Ligotke, M.W.; Pool, K.H.; McVeety, B.D.; Olsen, K.B.; Fruchter, J.S.; Goheen, S.C.

    1995-10-01

    This report describes inorganic and organic analyses results from in situ samples obtained from the headspace of the Hanford waste storage Tank 241-TX-118 (referred to as Tank TX-118). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH{sub 3}), nitrogen dioxide (NO{sub 2}), nitric oxide (NO), hydrogen cyanide (CHN), and water (H{sub 2}O). Sampling for sulfur oxides (SO{sub x}) was not requested. In addition, quantitative results were obtained for the 39 TO-14 compounds plus an additional 13 analytes. Hexane, normally included in the additional analytes, was removed because a calibration standard was not available during analysis of Tank TX-118 SUMMA{trademark} canisters. Of these, 12 were observed above the 5-ppbv reporting cutoff. Fourteen tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv and are reported with concentrations that are semiquantitative estimates based on internal-standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 86% of the total organic components in Tank TX-118. Permanent gas analysis was not conducted on the tank-headspace samples. Tank TX-118 is on both the Ferrocyanide and Organic Watch List.

  10. Functional expression of a recombinant toxin - rPnTx2-6 - active in erectile function in rat.

    PubMed

    Torres, F S; Silva, C N; Lanza, L F; Santos, Agenor V; Pimenta, A M C; De Lima, M E; Diniz, M R V

    2010-12-15

    In the current study, the putative cDNA for PnTx2-6 toxin of the Phoneutria nigriventer spider venom was cloned and expressed as tioredoxin fusion protein in the cytoplasm of Escherichia coli. The fusion protein was purified from the bacterial extracts by combination of immobilized Ni-ion affinity and gel filtration chromatographies. Then, it was cleaved by enterokinase and the generated recombinant PnTx2-6 (rPnTx2-6) was further purified by reverse-phase HPLC. Likewise the native toxin purified from the spider venom, rPnTx2-6 potentiates the erectile function when injected in rats. This result indicates that the production of functional recombinant PnTx2-6 might be an alternative to provide this basic and valuable tool for study, as well as for further understanding such complex physiological system, including its correlation with the central nervous system and local tissue factors. PMID:20417652

  11. Catching the fish - Constraining stellar parameters for TX Piscium using spectro-interferometric observations

    NASA Astrophysics Data System (ADS)

    Klotz, D.; Paladini, C.; Hron, J.; Aringer, B.; Sacuto, S.; Marigo, P.; Verhoelst, T.

    2013-02-01

    Context. Stellar parameter determination is a challenging task when dealing with galactic giant stars. The combination of different investigation techniques has proven to be a promising approach. Aims: We analyse archive spectra obtained with the Short Wavelength Spectrometer (SWS) onboard ISO, and new interferometric observations from the Very Large Telescope MID-infrared Interferometric instrument (VLTI/MIDI) of a very well studied carbon-rich giant: TX Psc. The aim of this work is to determine stellar parameters using spectroscopy and interferometry. Methods: The observations are used to constrain the model atmosphere, and eventually the stellar evolutionary model in the region where the tracks map the beginning of the carbon star sequence. Two different approaches are used to determine stellar parameters: (i) the "classic" interferometric approach where the effective temperature is fixed by using the angular diameter in the N-band (from interferometry) and the apparent bolometric magnitude; (ii) parameters are obtained by fitting a grid of state-of-the-art hydrostatic models to spectroscopic and interferometric observations. Results: We find good agreement between the parameters of the two methods. The effective temperature and luminosity clearly place TX Psc in the carbon-rich AGB star domain in the H-R-diagram. Current evolutionary tracks suggest that TX Psc became a C-star just recently, which means that the star is still in a "quiet" phase compared to the subsequent strong-wind regime. This agrees with the C/O ratio being only slightly greater than one. Based on observations made with ESO telescopes at Paranal Observatory under program IDs 74.D-0601, 60.A-9224, 77.C-0440, 60.A-9006, 78.D-0112, 84.D-0805.

  12. Tank 241-TX-104, cores 230 and 231 analytical results for the final report

    SciTech Connect

    Diaz, L.A.

    1998-07-07

    This document is the analytical laboratory report for tank 241-TX-104 push mode core segments collected between February 18, 1998 and February 23, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-104 Push Mode Core Sampling and Analysis Plan (TSAP) (McCain, 1997), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al., 1995) and the Safety Screening Data Quality Objective (DQO) (Dukelow, et.al., 1995). The analytical results are included in the data summary table. None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Alpha Activity (AT) exceeded notification limits as stated in the TSAP. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report. Appearance and Sample Handling Attachment 1 is a cross reference to relate the tank farm identification numbers to the 222-S Laboratory LabCore/LIMS sample numbers. The subsamples generated in the laboratory for analyses are identified in these diagrams with their sources shown. Core 230: Three push mode core segments were removed from tank 241-TX-104 riser 9A on February 18, 1998. Segments were received by the 222-S Laboratory on February 19, 1998. Two segments were expected for this core. However, due to poor sample recovery, an additional segment was taken and identified as 2A. Core 231: Four push mode core segments were removed from tank 241-TX-104 riser 13A between February 19, 1998 and February 23, 1998. Segments were received by the 222-S Laboratory on February 24, 1998. Two segments were expected for this core. However, due to poor sample recovery, additional segments were taken and identified as 2A and 2B. The TSAP states the core samples should be transported to the laboratory within three

  13. Evidence for large superhumps in TX Col and V4742 Sgr

    NASA Astrophysics Data System (ADS)

    Retter, Alon; Liu, Alexander; Bos, Marc

    Since the discovery of the largest positive superhump period in TV Col (6.4 h), we have started a program to search for superhumps in cataclysmic variables (CVs) with large orbital periods. In this work, we summarize preliminary results of our observations of TX Col and V4742 Sgr. TX Col is an intermediate polar with a 5.7-h orbital period. V4742 Sgr is a recent (2002) nova with no known periods. CCD unfiltered continuous photometry of these two objects was carried out during 56 nights (350 hours) in 2002-2003. The time series analysis reveals the presence of several periods in both power spectra. In TX Col, in addition to the orbital period of 5.7 h, we found peaks at 7.1 h and 5.0 h. These are interpreted as positive and negative superhumps correspondingly, although the effects of the quasi-periodic oscillations at ~2 h (which may cause spurious signals) were not taken into consideration. In the light curve of V4742 Sgr two long periods are detected - 6.1 and 5.4 h as well as a short-term period at 1.6 h. This result suggests that V4742 Sgr is an intermediate polar candidate and a permanent superhump system with a large orbital period (5.4 h) and a superhump period excess of 13%. If these results are confirmed, TX Col and V4742 Sgr join TV Col to form a group of intermediate polars with extremely large superhump periods. There seems to be now growing evidence that superhumps can occur in intermediate polars with long orbital periods, which is very likely inconsistent with the theoretical prediction that superhumps can only occur in systems with mass ratios below 0.33. Alternatively, if the mass ratio in these systems is nevertheless below the theoretical limit, they should harbour undermassive secondaries and very massive white dwarfs, near the Chandrasekhar limit, which would make them excellent candidates for progenitors of supernovae type Ia.

  14. Effects of Tityus serrulatus scorpion venom and its toxin TsTX-V on neurotransmitter uptake in vitro.

    PubMed

    Cecchini, Alessandra L; Vasconcelos, Flávio; Amara, Susan G; Giglio, José Roberto; Arantes, Eliane Candiani

    2006-12-01

    Scorpion neurotoxins targeting the Na(v) channel can be classified into two classes: alpha- and beta-neurotoxins and are reported as highly active in mammalian brain. In this work, we evaluate the effects of Tityus serrulatus venom (Ts venom) and its alpha-neurotoxin TsTX-V on gamma-aminobutyric acid (GABA), dopamine (DA) and glutamate (Glu) uptake in isolated rat brain synaptosomes. TsTX-V was isolated from Ts venom by ion exchange chromatography followed by reverse-phase (C18) high-performance liquid chromatography. Neither Ts venom nor TsTX-V was able to affect (3)H-Glu uptake. On the other hand, Ts venom (0.13 microg/mg) significantly inhibited both (3)H-GABA and (3)H-DA uptake ( approximately 50%). TsTX-V showed IC(50) values of 9.37 microM and 22.2 microM for the inhibition of (3)H-GABA and (3)H-DA uptake, respectively. These effects were abolished by pre-treatment with tetrodotoxin (TTX, 1 microM), indicating the involvement of voltage-gated Na(+) channels in this process. In the absence of Ca(2+), and at low Ts venom concentrations, the reduction of (3)H-GABA uptake was not as marked as in the presence of Ca(2+). TsTX-V did not reduce (3)H-GABA uptake in COS-7 cells expressing the GABA transporters GAT-1 and GAT-3, suggesting that this toxin indirectly reduces the transport. The reduced (3)H-GABA uptake by synaptosomes might be due to rapid cell depolarization as revealed by confocal microscopy of C6 glioma cells. Thus, TsTX-V causes a reduction of (3)H-GABA and (3)H-DA uptake in a Ca(2+)-dependent manner, not directly affecting GABA transporters, but, in consequence of depolarization, involving voltage-gated Na(+) channels.

  15. The type B brevetoxin (PbTx-3) adversely affects development, cardiovascular function, and survival in Medaka (Oryzias latipes) embryos.

    PubMed Central

    Colman, Jamie R; Ramsdell, John S

    2003-01-01

    Brevetoxins are produced by the red tide dinoflagellate Karenia brevis. The toxins are lipophilic polyether toxins that elicit a myriad of effects depending on the route of exposure and the target organism. Brevetoxins are therefore broadly toxic to marine and estuarine animals. By mimicking the maternal route of exposure to the oocytes in finfish, we characterized the adverse effects of the type B brevetoxin brevetoxin-3 (PbTx-3) on embryonic fish development and survival. The Japanese rice fish, medaka (Oryzias latipes), was used as the experimental model in which individual eggs were exposed via microinjection to various known concentrations of PbTx-3 dissolved in an oil vehicle. Embryos injected with doses exceeding 1.0 ng/egg displayed tachycardia, hyperkinetic twitches in the form of sustained convulsions, spinal curvature, clumping of the erythrocytes, and decreased hatching success. Furthermore, fish dosed with toxin were often unable to hatch in the classic tail-first fashion and emerged head first, which resulted in partial hatches and death. We determined that the LD(50) (dose that is lethal to 50% of the fish) for an injected dose of PbTx-3 is 4.0 ng/egg. The results of this study complement previous studies of the developmental toxicity of the type A brevetoxin brevetoxin-1 (PbTx-1), by illustrating in vivo the differing affinities of the two congeners for cardiac sodium channels. Consequently, we observed differing cardiovascular responses in the embryos, wherein embryos exposed to PbTx-3 exhibited persistent tachycardia, whereas embryos exposed to PbTx-1 displayed bradycardia, the onset of which was delayed. PMID:14644667

  16. Tank 241-TX-118, core 236 analytical results for the final report

    SciTech Connect

    ESCH, R.A.

    1998-11-19

    This document is the analytical laboratory report for tank 241-TX-118 push mode core segments collected between April 1, 1998 and April 13, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-118 Push Mode Core sampling and Analysis Plan (TSAP) (Benar, 1997), the Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al, 1995) and the Historical Model Evaluation Data Requirements (Historical DQO) (Sipson, et al., 1995). The analytical results are included in the data summary table (Table 1). None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Organic Carbon (TOC) exceeded notification limits as stated in the TSAP (Benar, 1997). One sample exceeded the Total Alpha Activity (AT) analysis notification limit of 38.4{micro}Ci/g (based on a bulk density of 1.6), core 236 segment 1 lower half solids (S98T001524). Appropriate notifications were made. Plutonium 239/240 analysis was requested as a secondary analysis. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report.

  17. Texture enhanced optimization-based image reconstruction (TxE-OBIR) from sparse projection views

    NASA Astrophysics Data System (ADS)

    Xie, Huiqiao; Niu, Tianye; Yang, Yi; Ren, Yi; Tang, Xiangyang

    2016-03-01

    The optimization-based image reconstruction (OBIR) has been proposed and investigated in recent years to reduce radiation dose in X-ray computed tomography (CT) through acquiring sparse projection views. However, the OBIR usually generates images with a quite different noise texture compared to the clinical widely used reconstruction method (i.e. filtered back-projection - FBP). This may make the radiologists/physicians less confident while they are making clinical decisions. Recognizing the fact that the X-ray photon noise statistics is relatively uniform across the detector cells, which is enabled by beam forming devices (e.g. bowtie filters), we propose and evaluate a novel and practical texture enhancement method in this work. In the texture enhanced optimization-based image reconstruction (TxEOBIR), we first reconstruct a texture image with the FBP algorithm from a full set of synthesized projection views of noise. Then, the TxE-OBIR image is generated by adding the texture image into the OBIR reconstruction. As qualitatively confirmed by visual inspection and quantitatively by noise power spectrum (NPS) evaluation, the proposed method can produce images with textures that are visually identical to those of the gold standard FBP images.

  18. Tank characterization report for single-shell tank 241-TX-104

    SciTech Connect

    FIELD, J.G.

    1999-05-12

    A major function of the Tank Waste Remediation System (TWRS) is to characterize waste in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis and other available information about a tank are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-TX-104. The objectives of this report are (1) to use characterization data in response to technical issues associated with tank 241-TX-104 waste, and (2) to provide a standard characterization of this waste in terms of a best-basis inventory estimate. Section 2.0 summarizes the response to technical issues, Section 3.0 shows the best-basis inventory estimate, Section 4.0 makes recommendations about the safety status of the tank and additional sampling needs. The appendices contain supporting data and information. This report supports the requirements of the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1997), Milestone M-44-15c, change request M-44-97-03 to ''issue characterization deliverables consistent with the Waste Information Requirements Document developed for FY 1999'' (Adams et al. 1998).

  19. PhTX-II a Basic Myotoxic Phospholipase A2 from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry

    PubMed Central

    Huancahuire-Vega, Salomón; Ponce-Soto, Luis Alberto; Marangoni, Sergio

    2014-01-01

    A monomeric basic PLA2 (PhTX-II) of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA2 enzyme class and displays conserved domains as the catalytic network, Ca2+-binding loop and the hydrophobic channel of access to the catalytic site, reflected in the high catalytic activity displayed by the enzyme. Moreover, PhTX-II PLA2 showed an allosteric behavior and its enzymatic activity was dependent on Ca2+. Examination of PhTX-II PLA2 by CD spectroscopy indicated a high content of alpha-helical structures, similar to the known structure of secreted phospholipase IIA group suggesting a similar folding. PhTX-II PLA2 causes neuromuscular blockade in avian neuromuscular preparations with a significant direct action on skeletal muscle function, as well as, induced local edema and myotoxicity, in mice. The treatment of PhTX-II by BPB resulted in complete loss of their catalytic activity that was accompanied by loss of their edematogenic effect. On the other hand, enzymatic activity of PhTX-II contributes to this neuromuscular blockade and local myotoxicity is dependent not only on enzymatic activity. These results show that PhTX-II is a myotoxic Asp49 PLA2 that contributes with toxic actions caused by P. hyoprora venom. PMID:25365526

  20. Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A2 from Bothrops pirajai venom

    PubMed Central

    2012-01-01

    Background Harpalycin 2 (HP-2) is an isoflavone isolated from the leaves of Harpalyce brasiliana Benth., a snakeroot found in northeast region of Brazil and used in folk medicine to treat snakebite. Its leaves are said to be anti-inflammatory. Secretory phospholipases A2 are important toxins found in snake venom and are structurally related to those found in inflammatory conditions in mammals, as in arthritis and atherosclerosis, and for this reason can be valuable tools for searching new anti-phospholipase A2 drugs. Methods HP-2 and piratoxin-III (PrTX-III) were purified through chromatographic techniques. The effect of HP-2 in the enzymatic activity of PrTX-III was carried out using 4-nitro-3-octanoyloxy-benzoic acid as the substrate. PrTX-III induced platelet aggregation was inhibited by HP-2 when compared to aristolochic acid and p-bromophenacyl bromide (p-BPB). In an attempt to elucidate how HP-2 interacts with PrTX-III, mass spectrometry, circular dichroism and intrinsic fluorescence analysis were performed. Docking scores of the ligands (HP-2, aristolochic acid and p-BPB) using PrTX-III as target were also calculated. Results HP-2 inhibited the enzymatic activity of PrTX-III (IC50 11.34 ± 0.28 μg/mL) although it did not form a stable chemical complex in the active site, since mass spectrometry measurements showed no difference between native (13,837.34 Da) and HP-2 treated PrTX-III (13,856.12 Da). A structural analysis of PrTX-III after treatment with HP-2 showed a decrease in dimerization and a slight protein unfolding. In the platelet aggregation assay, HP-2 previously incubated with PrTX-III inhibited the aggregation when compared with untreated protein. PrTX-III chemical treated with aristolochic acid and p-BPB, two standard PLA2 inhibitors, showed low inhibitory effects when compared with the HP-2 treatment. Docking scores corroborated these results, showing higher affinity of HP-2 for the PrTX-III target (PDB code: 1GMZ) than aristolochic

  1. 77 FR 72968 - Revisions to the California State Implementation Plan, for Imperial County, Placer County and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... County and Ventura County Air Pollution Control Districts AGENCY: Environmental Protection Agency (EPA... Imperial County Air Pollution Control District (ICAPCD), Placer County Air Pollution Control District (PCAPCD) and Ventura County Air Pollution Control District (PCAPCD) portions of the California...

  2. 33 CFR 165.T08-0240 - Safety Zone; Kemah Boardwalk Summer Season Fireworks, Galveston Bay, Kemah, TX.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Summer Season Fireworks, Galveston Bay, Kemah, TX. 165.T08-0240 Section 165.T08-0240 Navigation and... Areas Eighth Coast Guard District § 165.T08-0240 Safety Zone; Kemah Boardwalk Summer Season Fireworks...' radius around a fireworks barge located at approximate Latitude 29°32′57″ N, Longitude 095°00′31″ W....

  3. RCRA Assessment Plan for Single-Shell Tank Waste Management Area TX-TY at the Hanford Site

    SciTech Connect

    Hodges, Floyd N.; Chou, Charissa J.

    2001-02-23

    A groundwater quality assessment plan was prepared to investigate the rate and extent of aquifer contamination beneath Waste Management Area TX-TY on the Hanford Site in Washington State. This plan is an update of a draft plan issued in February 1999, which guided work performed in fiscal year 2000.

  4. 78 FR 45909 - Designation for the Amarillo, TX; Cairo, IL; Baton Rouge, LA; Raleigh, NC; and Belmond, IA Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ...)). SUPPLEMENTARY INFORMATION: In the December 28, 2012 Federal Register (77 FR 76453), GIPSA requested applications... Grain Inspection, Packers and Stockyards Administration Designation for the Amarillo, TX; Cairo, IL; Baton Rouge, LA; Raleigh, NC; and Belmond, IA Areas AGENCY: Grain Inspection, Packers and...

  5. 76 FR 33333 - Use of Small Area Fair Market Rents for Project Base Vouchers in the Dallas TX Metropolitan Area

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... URBAN DEVELOPMENT Use of Small Area Fair Market Rents for Project Base Vouchers in the Dallas TX...-8339. SUPPLEMENTARY INFORMATION: I. Background On August 4, 2010 (75 FR 46958), HUD published for... FR 27808) Federal Register notice. Specifically, HUD noted that the methodology for calculating...

  6. 78 FR 11816 - Foreign-Trade Zone 168-Dallas/Ft. Worth, TX, Authorization of Production Activity, Richemont...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ... Federal Register inviting public comment (77 FR 65360, 10/26/2012). The FTZ Board has determined that no... Activity, Richemont North America, Inc. dba Cartier (Eyewear Assembly/Kitting), Grand Prairie, TX On... North America, Inc. dba Cartier, within FTZ 168--Site 4, in Grand Prairie, Texas. ] The notification...

  7. 78 FR 73109 - Radio Broadcasting Services; Benjamin and Cisco, TX; De Beque, CO; Port Lions, AK; Rule and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-05

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Benjamin and Cisco, TX; De Beque, CO; Port Lions, AK... at De Beque, Colorado; Channel 237C3 at Benjamin, Texas; Channel 261C3 at Cisco, Texas; Channel 288C2..., Channel 237C3; by removing Cisco, Channel 261C3; by removing Channel 288C2 at Rule; and by...

  8. 76 FR 1519 - Security Zones; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... and Sabine-Neches Waterway, TX in the Federal Register (75 FR 29695). We received one comment on the... recommendation from that one comment and requesting further comments (75 FR 65232). No public meeting was... preamble, the Coast Guard adopts the interim rule amending 33 CFR part 165 that was published at 75...

  9. 75 FR 65232 - Security Zones; Sabine Bank Channel, Sabine Pass Channel and Sabine-Neches Waterway, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... public dockets in the January 17, 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do...-Neches Waterway, TX'' in the Federal Register (75 FR 29695). We received one comment on the proposed rule... facility located in Cameron Parish, LA. DATES: This interim rule is effective in the CFR on October...

  10. 75 FR 39662 - Foreign-Trade Subzone 116A-Port Arthur, TX; Expansion of Manufacturing Authority; Motiva...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... Foreign-Trade Zones Board Foreign-Trade Subzone 116A--Port Arthur, TX; Expansion of Manufacturing..., requesting an expansion of the scope of manufacturing authority approved within Subzone 116A, on behalf of... petrochemical feedstocks (Board Order 668, 59 FR 61, 12-3-1994, as amended by Board Order 740, 60 FR...

  11. Dielectric spectroscopy study on ionic liquid microemulsion composed of water, TX-100, and BmimPF6

    NASA Astrophysics Data System (ADS)

    Chen, Zhen; Nozaki, Ryusuke

    2012-06-01

    We report here a broadband dielectric spectroscopy study on an ionic liquid microemulsion (ILM) composed of water, Triton X-100 (TX-100), and 1-butyl-3-methylimidazolium hexafluorophosphate (bmimPF6). It is found that the phase behavior of this ILM can be easily identified by its dielectric response. The dielectric behavior of the ILM in the GHz range is consistent with that of TX-100/water mixtures with comparable water-to-TX-100 weight ratio. It consists of the relaxations due to ethylene oxide (EO) unit relaxation, hydration water dynamics, and/or free water dynamics. The water content dependence of the EO unit relaxation suggests that this relaxation involves dynamics of hydration water molecules. In the IL-in-water microemulsion phase, it is found that bmimPF6 molecules are preferentially dissolved in water when their concentration in water is lower than the solubility. An additional dielectric relaxation that is absent in the TX-100/water mixtures is observed in the frequency range of 107-108 Hz for this ILM. This low-frequency relaxation is found closely related to the bmimPF6 molecule and could be attributed to the hopping of its cations/anions between the anionic/cationic sites.

  12. Dielectric spectroscopy study on ionic liquid microemulsion composed of water, TX-100, and BmimPF6.

    PubMed

    Chen, Zhen; Nozaki, Ryusuke

    2012-06-28

    We report here a broadband dielectric spectroscopy study on an ionic liquid microemulsion (ILM) composed of water, Triton X-100 (TX-100), and 1-butyl-3-methylimidazolium hexafluorophosphate (bmimPF(6)). It is found that the phase behavior of this ILM can be easily identified by its dielectric response. The dielectric behavior of the ILM in the GHz range is consistent with that of TX-100∕water mixtures with comparable water-to-TX-100 weight ratio. It consists of the relaxations due to ethylene oxide (EO) unit relaxation, hydration water dynamics, and∕or free water dynamics. The water content dependence of the EO unit relaxation suggests that this relaxation involves dynamics of hydration water molecules. In the IL-in-water microemulsion phase, it is found that bmimPF(6) molecules are preferentially dissolved in water when their concentration in water is lower than the solubility. An additional dielectric relaxation that is absent in the TX-100∕water mixtures is observed in the frequency range of 10(7)-10(8) Hz for this ILM. This low-frequency relaxation is found closely related to the bmimPF(6) molecule and could be attributed to the hopping of its cations∕anions between the anionic∕cationic sites. PMID:22755585

  13. Neutron diffraction analysis of Nd3Fe29 - xTx (T=Ti, Cr, Mn)

    NASA Astrophysics Data System (ADS)

    Yelon, W. B.; Hu, Z.

    1996-02-01

    Rietveld analysis of neutron-diffraction data from Nd3Fe29-xTx (T=Ti, Cr, and Mn) has been used to determine the location of the substitutional atoms and the magnetic moments. Reanalysis of the T=Ti data confirms that the space group A2/m is a better choice than P21/c, which had previously been used to describe the structure. The Ti atom locations and concentrations remain unaffected in the two space groups, but for the other substituents the refined concentrations are well behaved in A2/m, whereas in P21/c the refinements were unstable due to the symmetry relations between certain substituted sites. The site occupancies are analyzed in terms of steric and environment effects. A possible explanation for the high Curie temperature of the Cr compound is proposed.

  14. Preliminary tank characterization report for single-shell tank 241-TX-108: best-basis inventory

    SciTech Connect

    Jo, J.

    1997-08-26

    This document is a preliminary Tank Characterization Report (TCR). It only contains the current best-basis inventory (Appendix D) for single-shell tank 241-TX-108. No TCR has been previously issued for this tank, and current core sample analyses are not available. The best-basis inventory, therefore, is based on an engineering assessment of waste type, process flowsheet data, and/or other available information. The Standard Inventories of Chemicals and Radionuclides in Hanford Site Tank Wastes describes standard methodology used to derive the tank-by-tank best-basis inventories. This preliminary TCR will be updated using this same methodology when additional data on tank contents become available.

  15. Snohomish County Biodiesel Project

    SciTech Connect

    Chang, Terrill; Carveth, Deanna

    2010-02-01

    Snohomish County in western Washington State began converting its vehicle fleet to use a blend of biodiesel and petroleum diesel in 2005. As prices for biodiesel rose due to increased demand for this cleaner-burning fuel, Snohomish County looked to its farmers to grow this fuel locally. Suitable seed crops that can be crushed to extract oil for use as biodiesel feedstock include canola, mustard, and camelina. The residue, or mash, has high value as an animal feed. County farmers began with 52 acres of canola and mustard crops in 2006, increasing to 250 acres and 356 tons in 2008. In 2009, this number decreased to about 150 acres and 300 tons due to increased price for mustard seed.

  16. Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A{sub 2} with low catalytic activity from Bothrops jararacussu venom

    SciTech Connect

    Corrêa, L. C.; Marchi-Salvador, D. P.; Cintra, A. C. O.; Soares, A. M.

    2006-08-01

    A myotoxic Asp49-PLA{sub 2} with low catalytic activity from B. jararacussu (BthTX-II) was crystallized in the monoclinic crystal system; a complete X-ray diffraction data set was collected and a molecular-replacement solution was obtained. The oligomeric structure of BthTX-II resembles those of the Asp49-PLA{sub 2} PrTX-III and all bothropic Lys49-PLA{sub 2}s. For the first time, a complete X-ray diffraction data set has been collected from a myotoxic Asp49-phospholipase A{sub 2} (Asp49-PLA{sub 2}) with low catalytic activity (BthTX-II from Bothrops jararacussu venom) and a molecular-replacement solution has been obtained with a dimer in the asymmetric unit. The quaternary structure of BthTX-II resembles the myotoxin Asp49-PLA{sub 2} PrTX-III (piratoxin III from B. pirajai venom) and all non-catalytic and myotoxic dimeric Lys49-PLA{sub 2}s. In contrast, the oligomeric structure of BthTX-II is different from the highly catalytic and non-myotoxic BthA-I (acidic PLA{sub 2} from B. jararacussu). Thus, comparison between these structures should add insight into the catalytic and myotoxic activities of bothropic PLA{sub 2}s.

  17. The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1{alpha} targeted gene expression

    SciTech Connect

    Miyake, Kotaro; Nishioka, Masanori; Imura, Satoru; Batmunkh, Erdenebulgan; Uto, Yoshihiro; Nagasawa, Hideko; Hori, Hitoshi; Shimada, Mitsuo

    2012-08-01

    Tumor hypoxia has been considered to be a potential therapeutic target, because hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. In the present study, we investigated the antitumor effect of a novel hypoxic cytotoxin, 3-[2-hydroxyethyl(methyl)amino]-2-quinoxalinecarbonitrile 1,4-dioxide (TX-2098) in inhibiting the expression of hypoxia inducible factor-1{alpha} (HIF-1{alpha}), and consequently vascular endothelial cell growth factor (VEGF) expression in pancreatic cancer. The antitumor effects of TX-2098 under hypoxia were tested against various human pancreatic cancer cell lines using WST-8 assay. VEGF protein induced pancreatic cancer was determined on cell-free supernatant by ELISA. Moreover, nude mice bearing subcutaneously (s.c.) or orthotopically implanted human SUIT-2 were treated with TX-2098. Tumor volume, survival and expression of HIF-1 and associated molecules were evaluated in treatment versus control groups. In vitro, TX-2098 inhibited the proliferation of various pancreatic cancer cell lines. In s.c model, tumors from nude mice injected with pancreatic cancer cells and treated with TX-2098 showed significant reductions in volume (P < 0.01 versus control). Quantitative real-time reverse transcription-PCR analysis revealed that TX-2098 significantly inhibited mRNA expression of the HIF-1 associated molecules, VEGF, glucose transporter 1 and Aldolase A (P < 0.01 versus control). These treatments also prolong the survival in orthotopic models. These results suggest that the effect of TX-2098 in pancreatic cancer might be correlated with the expression of VEGF and HIF-1 targeted molecules. -- Highlights: Black-Right-Pointing-Pointer We designed and synthesized novel hypoxic cytoxin, TX-2098. Black-Right-Pointing-Pointer TX-2098 inhibited the proliferation of human pancreatic cancer cells than TPZ. Black-Right-Pointing-Pointer TX-2098 reduced VEGF protein level than TPZ. Black-Right-Pointing-Pointer TX-2098

  18. Effects of Tityus serrulatus scorpion venom and its toxin TsTX-V on neurotransmitter uptake in vitro

    SciTech Connect

    Cecchini, Alessandra L.; Vasconcelos, Flavio; Giglio, Jose Roberto; Arantes, Eliane Candiani . E-mail: ecabraga@fcfrp.usp.br

    2006-12-01

    Scorpion neurotoxins targeting the Na{sub v} channel can be classified into two classes: {alpha}- and {beta}-neurotoxins and are reported as highly active in mammalian brain. In this work, we evaluate the effects of Tityus serrulatus venom (Ts venom) and its {alpha}-neurotoxin TsTX-V on {gamma}-aminobutyric acid (GABA), dopamine (DA) and glutamate (Glu) uptake in isolated rat brain synaptosomes. TsTX-V was isolated from Ts venom by ion exchange chromatography followed by reverse-phase (C18) high-performance liquid chromatography. Neither Ts venom nor TsTX-V was able to affect {sup 3}H-Glu uptake. On the other hand, Ts venom (0.13 {mu}g/mg) significantly inhibited both {sup 3}H-GABA and {sup 3}H-DA uptake ({approx} 50%). TsTX-V showed IC{sub 5} values of 9.37 {mu}M and 22.2 {mu}M for the inhibition of {sup 3}H-GABA and {sup 3}H-DA uptake, respectively. These effects were abolished by pre-treatment with tetrodotoxin (TTX, 1 {mu}M), indicating the involvement of voltage-gated Na{sup +} channels in this process. In the absence of Ca{sup 2+}, and at low Ts venom concentrations, the reduction of {sup 3}H-GABA uptake was not as marked as in the presence of Ca{sup 2+}. TsTX-V did not reduce {sup 3}H-GABA uptake in COS-7 cells expressing the GABA transporters GAT-1 and GAT-3, suggesting that this toxin indirectly reduces the transport. The reduced {sup 3}H-GABA uptake by synaptosomes might be due to rapid cell depolarization as revealed by confocal microscopy of C6 glioma cells. Thus, TsTX-V causes a reduction of {sup 3}H-GABA and {sup 3}H-DA uptake in a Ca{sup 2+}-dependent manner, not directly affecting GABA transporters, but, in consequence of depolarization, involving voltage-gated Na{sup +} channels.

  19. Borehole Data Package for 1998 Wells Installed at Single-Shell Tank Waste Management Area TX-TY

    SciTech Connect

    DG Horton; FN Hodges

    1999-03-23

    Four new Resource Conservation and Recovery Act (RCRA) groundwater monitoring wells were installed at the single-shell tank farm Waste Management Area (WMA) TX-TY during August through November of 1998 in fi,dfillment of Tri-Party Agreement (Eoology 1996) milestone M-24-38. The wells are 299-W1O-26, 299-W14-13, 299-W14-14, and 299-W15-40. Well 299-W1O-26 is located outside the east fence of the TY tank farm and replaces downgradient well299-W1O-18; well 299-W14-13 is located along the east fence near the northeast corner of the TX tank f- and replaces downgradient well 299-W14-12; well 299-W14-14 is located outside the east fence in the south ha.lfof the TX tank fiirm and is anew downgradient well; and well 299-W15-40 is located on the west side of the TX tank farm and is anew upgradient well. The locations of all wells in the monitoring network are shown on Figure 1. The groundwater monitoring plan for WMA TX-TY (Caggiano and Goodwin 1991) describes the hydrogeology of the 200 West Area and WMA TX-TY. An Interim Change Notice to the groundwater monitoring plan provides justification for the new wells. The new wells were constructed to the speciii- cations and requirements described in Washington Administrative Code (WAC) 173-160 and WAC 173-303. This document compiles &fiormation on the drilling and construction, well development pump instal- latio~ groundwater sampling, and sediment testing applicable to wells 299-W1O-26, 299-W14-13, 299-W14-14, and 299-W15-40. Appendix A contains the geologist's log, the Well Construction Sum- mary Repo~ and Well Summary Sheet (as-built diagram); Appendix B contains results of laboratory analyses of particle size distribution, p~ conductivity, calcium carbonate conten~ major cation and anion concentrations from 1:1 water: sediment extracts, and moisture conten~ Appendix C contains geophysical logs; and Appendix D contains the analytical results from groundwater samples obtained during well construction. Aqutier tests (slug tests

  20. 77 FR 48960 - Foreign-Trade Zone 12-McAllen, TX Notification of Proposed Export Production Activity TST NA Trim...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... Activity TST NA Trim, LLC (Fabric/Leather Lamination and Cutting) Hidalgo, TX The McAllen Foreign Trade... coated) polyester knit, polyester warp knit (pile), polyester and nylon warp knit, and leather (duty...

  1. TxDOT Goes Beyond Compliance by Purchasing 100% AFVs. EPAct Fleet Information and Regulations, State& Alternative Fuel Provider Program Success Story

    SciTech Connect

    Not Available

    2002-01-01

    Fact sheet features the challenges the Texas Department of Transportation (TxDOT) faced and overcame in complying to a Texas legislation that calls for the acquisition of only alternative fuel vehicles.

  2. The complex environment of the bright carbon star TX Piscium as probed by spectro-astrometry

    NASA Astrophysics Data System (ADS)

    Hron, J.; Uttenthaler, S.; Aringer, B.; Klotz, D.; Lebzelter, T.; Paladini, C.; Wiedemann, G.

    2015-12-01

    Context. Stars on the asymptotic giant branch (AGB) show broad evidence of inhomogeneous atmospheres and circumstellar envelopes. These have been studied by a variety of methods on various angular scales. In this paper we explore the envelope of the well-studied carbon star TX Psc by the technique of spectro-astrometry. Aims: We explore the potential of this method for detecting asymmetries around AGB stars. Methods: We obtained CRIRES observations of several CO Δv = 1 lines near 4.6 μm and HCN lines near 3 μm in 2010 and 2013. These were then searched for spectro-astrometric signatures. For the interpretation of the results, we used simple simulated observations. Results: Several lines show significant photocentre shifts with a clear dependence on position angle. In all cases, tilde-shaped signatures are found where the positive and negative shifts (at PA 0°) are associated with blue and weaker red components of the lines. The shifts can be modelled with a bright blob 70 mas to 210 mas south of the star with a flux of several percent of the photospheric flux. We estimate a lower limit of the blob temperature of 1000 K. The blob may be related to a mass ejection as found for AGB stars or red supergiants. We also consider the scenario of a companion object. Conclusions: Although there is clear spectro-astrometric evidence of a rather prominent structure near TX Psc, it does not seem to relate to the other evidence of asymmetries, so no definite explanation can be given. Our data thus underline the very complex structure of the environment of this star, but further observations that sample the angular scales out to a few hundred milli-arcseconds are needed to get a clearer picture. Based on observations made with ESO telescopes at La Silla Paranal Observatory under programme IDs 386.D-0091 and 091.D-0094.Appendix A is available in electronic form at http://www.aanda.org

  3. Emissions of Fine Particulate Matter From Motor Vehicles: A Tunnel study in Houston, TX

    NASA Astrophysics Data System (ADS)

    Kulkarni, P.; Chellam, S.; Fraser, M. P.

    2004-05-01

    The objective of this research is to identify individual organic compounds and trace metals emitted as PM2.5 from motor vehicles that can serve as tracers in order to quantify the relative contributions of diesel and gasoline engines to PM2.5 emissions in the Houston, TX area. We report results from a systematic analysis of PM2.5 emitted from vehicles in a highway tunnel in Houston, TX, viz. Washburn tunnel. PM2.5 emissions were speciated in terms of individual organic compounds including 14 n-alkanes, 12 polycyclic aromatic hydrocarbons (PAHs), and 9 petroleum biomarkers using Gas Chromatography-Mass Spectrometry as well as 16 metals using Inductively Coupled-Plasma Mass Spectrometry (ICP-MS). PM2.5 samples were digested using a technique developed by us that eliminates direct handling of hydrofluoric acid. HF was first generated in situ at high temperature and pressure in closed Teflon liners by heating a mixture of NaF, HNO3, and sample and then complexing any remaining HF using H3BO3. We have recently reported that this method is capable of completely extracting trace elements from airborne particulate matter prior to analysis using ICP-MS. Potential tracers were first identified using an exploratory multivariate dimensionality reduction technique called Principal Component Analysis (PCA). PCA results were also physically interpreted by calculating emission indices. Among the possible marker compounds identified by PCA for use in separating diesel and gasoline fine particulate matter, emission indices of 5 n-alkanes, (n-heneicosane, n-docosane, n-tricosane, n-tetracosane, and n-pentacosane), and 2 PAHs, (fluoranthene and pyrene) were strongly and positively correlated with the amount of carbon emanating from diesel vehicles. This suggests that these compounds can be used as molecular markers for diesel engine emissions. PCA of trace metal concentrations showed that Zn, Cu, and Ba can be attributed to direct vehicle emissions. However, emission index

  4. Evaluation of integrated respiratory gating systems on a Novalis Tx system.

    PubMed

    Chang, Zheng; Liu, Tonghai; Cai, Jing; Chen, Qing; Wang, Zhiheng; Yin, Fang-Fang

    2011-04-04

    The purpose of this study was to investigate the accuracy of motion tracking and radiation delivery control of integrated gating systems on a Novalis Tx system. The study was performed on a Novalis Tx system, which is equipped with Varian Real-time Position Management (RPM) system, and BrainLAB ExacTrac gating systems. In this study, the two systems were assessed on accuracy of both motion tracking and radiation delivery control. To evaluate motion tracking, two artificial motion profiles and five patients' respiratory profiles were used. The motion trajectories acquired by the two gating systems were compared against the references. To assess radiation delivery control, time delays were measured using a single-exposure method. More specifically, radiation is delivered with a 4 mm diameter cone within the phase range of 10%-45% for the BrainLAB ExacTrac system, and within the phase range of 0%-25% for the Varian RPM system during expiration, each for three times. Radiochromic films were used to record the radiation exposures and to calculate the time delays. In the work, the discrepancies were quantified using the parameters of mean and standard deviation (SD). Pearson's product-moment correlational analysis was used to test correlation of the data, which is quantified using a parameter of r. The trajectory profiles acquired by the gating systems show good agreement with those reference profiles. A quantitative analysis shows that the average mean discrepancies between BrainLAB ExacTrac system and known references are 1.5 mm and 1.9 mm for artificial and patient profiles, with the maximum motion amplitude of 28.0 mm. As for the Varian RPM system, the corresponding average mean discrepancies are 1.1 mm and 1.7 mm for artificial and patient profiles. With the proposed single-exposure method, the time delays are found to be 0.20 ± 0.03 seconds and 0.09 ± 0.01 seconds for BrainLAB ExacTrac and Varian RPM systems, respectively. The results indicate the systems can

  5. Rapidly characterizing the fast dynamics of RNA genetic circuitry with cell-free transcription-translation (TX-TL) systems.

    PubMed

    Takahashi, Melissa K; Chappell, James; Hayes, Clarmyra A; Sun, Zachary Z; Kim, Jongmin; Singhal, Vipul; Spring, Kevin J; Al-Khabouri, Shaima; Fall, Christopher P; Noireaux, Vincent; Murray, Richard M; Lucks, Julius B

    2015-05-15

    RNA regulators are emerging as powerful tools to engineer synthetic genetic networks or rewire existing ones. A potential strength of RNA networks is that they may be able to propagate signals on time scales that are set by the fast degradation rates of RNAs. However, a current bottleneck to verifying this potential is the slow design-build-test cycle of evaluating these networks in vivo. Here, we adapt an Escherichia coli-based cell-free transcription-translation (TX-TL) system for rapidly prototyping RNA networks. We used this system to measure the response time of an RNA transcription cascade to be approximately five minutes per step of the cascade. We also show that this response time can be adjusted with temperature and regulator threshold tuning. Finally, we use TX-TL to prototype a new RNA network, an RNA single input module, and show that this network temporally stages the expression of two genes in vivo.

  6. Photoinduced electron and energy transfer from coumarin 153 to perylenetetracarboxylic diimide in bmimPF6/TX-100/water microemulsions.

    PubMed

    Wu, Haixia; Wang, Haixia; Xue, Lin; Li, Xiyou

    2011-01-15

    A perylenetetracarboxylic diimide (PDI) compound with an attached hydrophilic polyoxyethylene group at the imide nitrogen position was designed and synthesized. Photoinduced electron and energy transfer between coumarin 153 (C-153) and PDI in a ternary microemulsion with an ionic liquid (bmimPF(6)/TX-100/H(2)O) were investigated by steady state electronic absorption and fluorescence spectroscopy. The results revealed that both PDI and C-153 resided at the interface between the surfactant TX-100 and the ionic liquid bmimPF(6) in the ternary microemulsions. The absorption spectra suggested no interactions between C-153 and PDI in the ground states, but the fluorescence spectra revealed the presence of an efficient electron transfer and a less efficient energy transfer from C-153 to PDI. Moreover, the electron transfer was much more efficient in microemulsions than that in homogeneous conventional organic solvents due to the unique micro-environment of the microemulsion. PMID:20965513

  7. PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a.

    PubMed

    McCarthy, Claudia A; Rash, Lachlan D; Chassagnon, Irène R; King, Glenn F; Widdop, Robert E

    2015-12-01

    Acid-sensing ion channel 1a (ASIC1a) is the primary acid sensor in mammalian brain and plays a major role in neuronal injury following cerebral ischemia. Evidence that inhibition of ASIC1a might be neuroprotective following stroke was previously obtained using "PcTx1 venom" from the tarantula Psalmopeous cambridgei. We show here that the ASIC1a-selective blocker PcTx1 is present at only 0.4% abundance in this venom, leading to uncertainty as to whether the observed neuroprotective effects were due to PcTx1 blockade of ASIC1a or inhibition of other ion channels and receptors by the hundreds of peptides and small molecules present in the venom. We therefore examined whether pure PcTx1 is neuroprotective in a conscious model of stroke via direct inhibition of ASIC1a. A focal reperfusion model of stroke was induced in conscious spontaneously hypertensive rats (SHR) by administering endothelin-1 to the middle cerebral artery via a surgically implanted cannula. Two hours later, SHR were treated with a single intracerebroventricular (i.c.v.) dose of PcTx1 (1 ng/kg), an ASIC1a-inactive mutant of PcTx1 (1 ng/kg), or saline, and ledged beam and neurological tests were used to assess the severity of symptomatic changes. PcTx1 markedly reduced cortical and striatal infarct volumes measured 72 h post-stroke, which correlated with improvements in neurological score, motor function and preservation of neuronal architecture. In contrast, the inactive PcTx1 analogue had no effect on stroke outcome. This is the first demonstration that selective pharmacological inhibition of ASIC1a is neuroprotective in conscious SHRs, thus validating inhibition of ASIC1a as a potential treatment for stroke. PMID:26320544

  8. The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a

    PubMed Central

    Salinas, Miguel; Rash, Lachlan D; Baron, Anne; Lambeau, Gérard; Escoubas, Pierre; Lazdunski, Michel

    2006-01-01

    Acid-sensing ion channels (ASICs) are excitatory neuronal cation channels, involved in physiopathological processes related to extracellular pH fluctuation such as nociception, ischaemia, perception of sour taste and synaptic transmission. The spider peptide toxin psalmotoxin 1 (PcTx1) has previously been shown to inhibit specifically the proton-gated cation channel ASIC1a. To identify the binding site of PcTx1, we produced an iodinated form of the toxin (125I-PcTx1YN) and developed a set of binding and electrophysiological experiments on several chimeras of ASIC1a and the PcTx1-insensitive channels ASIC1b and ASIC2a. We show that 125I-PcTx1YN binds specifically to ASIC1a at a single site, with an IC50 of 128 pm, distinct from the amiloride blocking site. Results obtained from chimeras indicate that PcTx1 does not bind to ASIC1a transmembrane domains (M1 and M2), involved in formation of the ion pore, but binds principally on both cysteine-rich domains I and II (CRDI and CRDII) of the extracellular loop. The post-M1 and pre-M2 regions, although not involved in the binding site, are crucial for the ability of PcTx1 to inhibit ASIC1a current. The linker domain between CRDI and CRDII is important for their correct spatial positioning to form the PcTx1 binding site. These results will be useful for the future identification or design of new molecules acting on ASICs. PMID:16284080

  9. VdTX-1, a reversible nicotinic receptor antagonist isolated from venom of the spider Vitalius dubius (Theraphosidae).

    PubMed

    Rocha-E-Silva, Thomaz A A; Rostelato-Ferreira, Sandro; Leite, Gildo B; da Silva, Pedro Ismael; Hyslop, Stephen; Rodrigues-Simioni, Léa

    2013-08-01

    Theraphosid spider venoms can block neurotransmission in vertebrate nerve-muscle preparations in vitro, but few of the components involved have been characterized. In this work, we describe the neuromuscular activity of venom from the Brazilian theraphosid Vitalius dubius and report the purification and pharmacological characterization of VdTX-1, a 728 Da toxin that blocks nicotinic receptors. Neuromuscular activity was assayed in chick biventer cervicis preparations and muscle responses to exogenous ACh and KCl were determined before and after incubation with venom or toxin. Changes in membrane resting potential were studied in mouse diaphragm muscle. The toxin was purified by a combination of filtration through Amicon® filters, cation exchange HPLC and RP-HPLC; toxin purity and mass were confirmed by mass spectrometry. Venom caused progressive neuromuscular blockade and muscle contracture; the blockade but not the contracture was reversible by washing. Venom attenuated contractures to exogenous ACh and KCl. Filtration yielded low (LM, <5 kDa) and high (HM, >5 kDa) fractions, with the latter reproducing the contracture seen in venom but with a slight and progressive twitch blockade. The LM fraction caused reversible blockade and attenuated contractures to ACh, but had no effect on contractures to KCl. VdTX-1 (728 Da) purified from the LM fraction was photosensitive and reduced the E(max) to ACh in biventer cervicis muscle without affecting the EC₅₀; VdTX-1 also abolished carbachol-induced depolarizations. V. dubius venom contains at least two components that affect vertebrate neurotransmission. One component, VdTX-1, blocks nicotinic receptors non-competitively to produce reversible blockade without muscle contracture.

  10. Reduced subcommissural organ glycoprotein immunoreactivity precedes aqueduct closure and ventricular dilatation in H-Tx rat hydrocephalus.

    PubMed

    Somera, K C; Jones, H C

    2004-03-01

    The H-Tx rat has fetal-onset hydrocephalus associated with closure of the cerebral aqueduct and a reduction in the secretory cells of the subcommissural organ (SCO), a circumventricular organ situated in the dorsal wall of the cerebral aqueduct. The objective of this study was to determine the role of the SCO in hydrocephalus pathogenesis. Serial brain sections through aqueduct regions containing the SCO from H-Tx rats, together with non-hydrocephalic Fischer F344 rats, were studied at E16, before hydrocephalus onset, at E17, the beginning of onset, and at P0 when the hydrocephalus was overt. Tissues were immunostained by AFRU, an antibody against the SCO glycoprotein, and for the intermediate filament nestin. The area of SCO cells with AFRU immunostaining and the severity of lateral ventricle dilatation were quantified by image analysis. At E16 all fetuses had distinct SCO ependymal cells, open aqueducts and normal lateral ventricles. The H-Tx fetuses fell into two groups with large areas and small areas of AFRU immunoreactivity, all with a full complement of SCO cells. By E17, fetuses with small areas of immunoreactivity had reduced numbers of tall SCO secretory cells, and most had aqueducts closed posteriorly and dilated ventricles. Three additional fetuses with small areas of immunoreactivity had narrow but patent aqueducts and normal ventricles, and another had an open aqueduct and dilated ventricles. At P0, pups previously identified as hydrocephalic had small areas of AFRU immunoreactivity, an aqueduct that was closed anteriorly but open posteriorly, ventricular dilatation, and an absence of SCO secretory cells. The aqueduct even when closed was lined by typical ependymal cells throughout. Decreased nestin immunostaining accompanied the SCO changes. It is concluded that reduced SCO glycoprotein immunoreactivity precedes both aqueduct closure and expansion of the lateral ventricles in the H-Tx rat.

  11. Vapor space characterization of waste tank 241-TX-118: Results from samples collected on 12/16/94

    SciTech Connect

    Lucke, R.B.; Ligotke, M.W.; McVeety, B.D.

    1995-10-01

    This report describes inorganic and organic analyses results from samples obtained from the headspace of the Hanford waste storage Tank 241-TX-118 (referred to as Tank TX-118). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH{sub 3}), nitrogen dioxide (NO{sub 2}), nitric oxide (NO), and water (H{sub 2}O). Sampling for hydrogen cyanide (HCN) and sulfur oxides (SO{sub x}) was not requested. In addition, quantitative results were obtained for the 39 TO-14 compounds plus an additional 14 analytes. Of these, 3 were observed above the 5-ppbv reporting cutoff. Twenty three organic tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv, and are reported with concentrations that are semiquantitative estimates based on internal-standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 84% of the total organic components in Tank TX-118. Two permanent gases, carbon dioxide (CO{sub 2}) and nitrous oxide (N{sub 2}O), were also detected.

  12. Structural studies of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/ p-xylene ionic liquid microemulsions.

    PubMed

    Gao, Yan'an; Zhang, Jin; Xu, Hongyan; Zhao, Xueyan; Zheng, Liqiang; Li, Xinwei; Yu, Li

    2006-07-17

    The ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate (bmimBF4) forms nonaqueous microemulsions with p-xylene, with the aid of the nonionic surfactant TX-100. The phase behavior of the ternary system is investigated, and three microregions of the microemulsions-ionic liquid-in-oil (IL/O), bicontinuous, and oil-in-ionic liquid (O/IL)-are identified by conductivity measurements, according to percolation theory. On the basis of a phase diagram, a series of IL/O microemulsions are chosen and characterized by dynamic light scattering (DLS). The size of aggregates increases on increasing the amount of added polar component (bmimBF(4)), which is a similar phenomenon to that observed for typical water-in-oil (W/O) microemulsions, suggesting the formation of IL/O microemulsions. The microstructural characteristics of the microemulsions are investigated by FTIR and 1H NMR spectroscopy. The results indicate that the interaction between the electronegative oxygen atoms of the oxyethylene (OE) units in TX-100 and the electropositive imidazolium ring may be the driving force for the solubilization of bmimBF4 into the core of the TX-100 aggregates. In addition, the micropolarity of the microemulsions is investigated by using methyl orange (MO) as a UV/Vis spectroscopic probe. A relatively constant polarity of the microemulsion droplets is obtained in the IL microemulsion. Finally, a plausible structure for the IL/O microemulsion is presented. PMID:16789041

  13. Mono County update

    SciTech Connect

    Lyster, D.L.

    1987-06-01

    On February 9, 1988, the Mono County Board of Supervisors voted to approve Bonneville Pacific Corporation's Mammoth Chance Geothermal Project. The project is an air-cooled, binary, geothermal power plant, 10 megawatts, net. The Mono County Board of Supervisors issued a project use-permit with vigorous and stringent conditions. Specific emphasis was placed on the establishment of a monitoring program designed to detect the effects of geothermal development on the springs at the Hot Creek Fish Hatchery and Hot Creek Gorge. On October 5, 1987, the Mono County Planning Commission granted a use-permit to Mammoth Pacific for its Mammoth Pacific II Project, a binary, air-cooled, geothermal power plant, 10 megawatts, net. The issuance of the use-permit instigated an appeal by the Sierra Club. That appeal was heard on February 22, 1988, At the end of the testimony, the Board of Supervisors voted to uphold the appeal of the Sierra Club, thereby denying the project by a vote of 3 to 2. The main areas of concern voiced by the majority of the Board included potential hydrologic impacts to Hot Creek Gorge and Hot Creek Fish Hatchery, visual impacts, and impacts to mule deer migration and survival. One of the options now available to Mammoth Pacific is to request that the project be denied without prejudice. This would allow Mammoth Pacific to return to the Board immediately with additional material regarding its concerns.

  14. Reservoir fracture mapping using microearthquakes: Austin chalk, Giddings field, TX and 76 field, Clinton Co., KY

    SciTech Connect

    Phillips, W.S.; Rutledge, J.T.; Fairbanks, T.D.

    1996-12-31

    Patterns of microearthquakes detected downhole defined fracture orientation and extent in the Austin chalk, Giddings field, TX and the 76 field, Clinton Co., KY. We collected over 480 and 770 microearthquakes during hydraulic stimulation at two sites in the Austin chalk, and over 3200 during primary production in Clinton Co. Data were of high enough quality that 20%, 31% and 53% of the events could be located, respectively. Reflected waves constrained microearthquakes to the stimulated depths at the base of the Austin chalk. In plan view, microearthquakes defined elongate fracture zones extending from the stimulation wells parallel to the regional fracture trend. However, widths of the stimulated zones differed by a factor of live between the two Austin chalk sites, indicating a large difference in the population of ancillary fractures. Post-stimulation production was much higher from the wider zone. At Clinton Co., microearthquakes defined low-angle, reverse-fault fracture zones above and below a producing zone. Associations with depleted production intervals indicated the mapped fractures had been previously drained. Drilling showed that the fractures currently contain brine. The seismic behavior was consistent with poroelastic models that predicted slight increases in compressive stress above and below the drained volume.

  15. Reservoir fracture mapping using microearthquakes: Austin chalk, Giddings field, TX and 76 field, Clinton Co., KY

    SciTech Connect

    Phillips, W.S.; Rutledge, J.T.; Gardner, T.L.; Fairbanks, T.D.; Miller, M.E.; Schuessler, B.K.

    1996-11-01

    Patterns of microearthquakes detected downhole defined fracture orientation and extent in the Austin chalk, Giddings field, TX and the 76 field, Clinton Co., KY. We collected over 480 and 770 microearthquakes during hydraulic stimulation at two sites in the Austin chalk, and over 3200 during primary production in Clinton Co. Data were of high enough quality that 20%, 31% and 53% of the events could be located, respectively. Reflected waves constrained microearthquakes to the stimulated depths at the base of the Austin chalk. In plan view, microearthquakes defined elongate fracture zones extending from the stimulation wells parallel to the regional fracture trend. However, widths of the stimulated zones differed by a factor of five between the two Austin chalk sites, indicating a large difference in the population of ancillary fractures. Post-stimulation production was much higher from the wider zone. At Clinton Co., microearthquakes defined low-angle, reverse-fault fracture zones above and below a producing zone. Associations with depleted production intervals indicated the mapped fractures had been previously drained. Drilling showed that the fractures currently contain brine. The seismic behavior was consistent with poroelastic models that predicted slight increases in compressive stress above and below the drained volume.

  16. Impacts of Hurricane Ike on the beaches of the Bolivar Peninsula, TX, USA

    NASA Astrophysics Data System (ADS)

    Sherman, Douglas J.; Hales, Billy U.; Potts, Michael K.; Ellis, Jean T.; Liu, Hongxing; Houser, Chris

    2013-10-01

    Hurricane Ike caused substantial beach erosion along the coast of the Bolivar Peninsula, TX. Much of the erosion was caused by the offshore (ebb) flow of the ca. 5 m storm surge that formed spatially discrete scour features. Using aerial photography and repeat LiDAR data, we identify five types of scour features and describe the alongshore distribution in four flow environments. Type 1 scours are relatively small and compact features associated mainly with flow off a wide, vegetated (grasses, shrubs, trees) surface across a wide beach. Type 2 scours are large and branching forms associated mainly with flow that was channeled by streets or gaps between structures. Type 3 scours are large and blocky features associated with flow off a marsh surface, across a highway, which removed almost all beach sands from the surface. Type 4 scours are elongated, shore perpendicular channels associated with the same flow characteristics as Type 3 scours. Type 5 scours are elongated, shore-perpendicular features, sometimes branching, associated with flow through gaps in a destroyed shore protection structure. Repeat imagery indicates that many of the features persisted for at least seven months. Recent aerial photography indicates that aspects of some features remained evident more than three years after Ike's landfall.

  17. Radical Budget and Ozone Production in Houston, TX during SHARP 2009

    NASA Astrophysics Data System (ADS)

    Ren, X.; van Duin, D.; Cazorla, M.; Chen, S.; Brune, W. H.; Flynn, J. H.; Lefer, B. L.; Dibb, J. E.; Wong, K.; Tsai, C.; Stutz, J.

    2010-12-01

    The chemistry of atmospheric radicals, especially the hydroxyl radical (OH) and hydroperoxyl radical (HO2), together called HOx, is deeply involved in the formation of the secondary pollutants ozone and fine particles. Radical precursors such as nitrous acid (HONO) and formaldehyde (HCHO) significantly affects HOx budget in urban environments like Houston. These chemical processes connect surface emissions, both human and natural, to local and regional pollution, and climate change. Using the data collected during the Study of Houston Atmospheric Radical Precursors (SHARP) in Houston, TX in spring 2009, we test our understanding of photochemistry through the analysis of the radical budget and ozone production. A numerical box model was used to simulate the oxidation processes and observed OH and HO2 during this study. Using the model results, we calculate the radical budget and analyze the sensitivity of ozone production to nitrogen oxides (NOx) and volatile organic compounds (VOCs). The radical budget shows that the photolysis of HONO and the photolysis of HCHO were significant HOx sources in this urban environment. We also compare the observed OH reactivity and ozone production rate to the model calculations. In general, ozone production rate was VOC limited in the morning and NOx limited in the afternoon. This relationship results from the ratio of VOCs to NOx in Houston. Results from this study provide additional support for regulatory actions to reduce reactive VOCs in Houston in order to reduce ozone and other secondary pollutants.

  18. Nanoscale elastic changes in 2D Ti3C2Tx (MXene) pseudocapacitive electrodes

    DOE PAGES

    Come, Jeremy; Xie, Yu; Naguib, Michael; Jesse, Stephen; Kalinin, Sergei V.; Gogotsi, Yury; Kent, Paul R. C.; Balke, Nina

    2016-02-01

    Designing sustainable electrodes for next generation energy storage devices relies on the understanding of their fundamental properties at the nanoscale, including the comprehension of ions insertion into the electrode and their interactions with the active material. One consequence of ion storage is the change in the electrode volume resulting in mechanical strain and stress that can strongly affect the cycle life. Therefore, it is important to understand the changes of dimensions and mechanical properties occurring during electrochemical reactions. While the characterization of mechanical properties via macroscopic measurements is well documented, in-situ characterization of their evolution has never been achieved atmore » the nanoscale. Two dimensional (2D) carbides, known as MXenes, are promising materials for supercapacitors and various kinds of batteries, and understating the coupling between their mechanical and electrochemical properties is therefore necessary. Here we report on in-situ imaging, combined with density functional theory of the elastic changes, of a 2D titanium carbide (Ti3C2Tx) electrode in direction normal to the basal plane during cation intercalation. The results show a strong correlation between the Li+ ions content and the elastic modulus, whereas little effects of K+ ions are observed. Moreover, this strategy enables identifying the preferential intercalation pathways within a single particle.« less

  19. Vertical spin Hall magnetoresistance in T a1 -xP tx/YIG bilayers

    NASA Astrophysics Data System (ADS)

    Han, J. H.; Shi, G. Y.; Zhou, X. J.; Yang, Q. H.; Rao, Y. H.; Li, G.; Zhang, H. W.; Pan, F.; Song, C.

    2016-10-01

    The spin Hall effect and the magnetic proximity effect are two main sources of the magnetoresistance (MR) effects in heavy metal/ferromagnet bilayers, where they play isolated roles but are usually contaminated by each other. In T a1-xP tx/YIG (=Y3F e5O12) bilayers consisting of Ta and Pt nanograins, these effects are intrinsically coupled to generate new MR with 360° direction sensitivity to the magnetic field and proportionality to the out-of-plane magnetization of YIG. Due to the opposite spin Hall angle of Ta and Pt, vertical spin accumulation is generated via the spin Hall effect at the transverse boundaries between Ta and Pt grains. The spin-dependent scattering by the proximity-induced Pt magnetization finally leads to the MR, which is named as vertical spin Hall MR taking the role of spin Hall angle into account. Besides fundamental insight to spin transport physics, our work provides an approach to detecting perpendicular magnetization in a variety of magnets.

  20. 77 FR 73005 - Revisions to the California State Implementation Plan, Imperial County, Placer County, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... County, and Ventura County Air Pollution Control Districts AGENCY: Environmental Protection Agency (EPA... Pollution Control District (ICAPCD), Placer County Air Pollution Control District (PCAPCD) and Ventura County Air Pollution Control District (PCAPCD) portions of the California State Implementation Plan...

  1. Hydrology of Lake County, Florida

    USGS Publications Warehouse

    Knochenmus, Darwin D.; Hughes, G.H.

    1976-01-01

    Lake County includes a 1,150 square-mile area consisting of ridges, uplands, and valleys in central-peninsular Florida. About 32 percent of the county is covered by lakes, swamps, and marshes. Water requirements in 1970 averaged about 54 million gallons per day. About 85 percent of the water was obtained from wells; about 15 percent from lakes. The Floridan aquifer supplies almost all the ground water used in Lake County. Annual recharge to the Floridan aquifer averages about 7 inches over the county; runoff average 8.5 inches. The quality of ground and surface water in Lake County is in general good enough for most uses; however, the poor quality of Floridan-aquifer water in the St. John River Valley probably results from the upward movement of saline water along a fault zone. Surface water in Lake County is usually less mineralized than ground water but is more turbid and colored. (Woodard-USGS)

  2. Isolation and characterization of SsmTx-I, a Specific Kv2.1 blocker from the venom of the centipede Scolopendra Subspinipes Mutilans L. Koch.

    PubMed

    Chen, Minzhi; Li, Jing; Zhang, Fan; Liu, Zhonghua

    2014-03-01

    Scolopendra subspinipes mutilans, also known as Chinese red-headed centipede, is a venomous centipede from East Asia and Australasia. Venom from this animal has not been researched as thoroughly as venom from snakes, snails, scorpions, and spiders. In this study, we isolated and characterized SsmTx-I, a novel neurotoxin from the venom of S. subspinipes mutilans. SsmTx-I contains 36 residues with four cysteines forming two disulfide bonds. It had low sequence similarity (<10%) with other identified peptide toxins. By whole-cell recording, SsmTx-I significantly blocked voltage-gated K⁺ channels in dorsal root ganglion neurons with an IC₅₀ value of 200 nM, but it had no effect on voltage-gated Na⁺ channels. Among the nine K⁺ channel subtypes expressed in human embryonic kidney 293 cells, SsmTx-I selectively blocked the Kv2.1 current with an IC₅₀ value of 41.7 nM, but it had little effect on currents mediated by other K⁺ channel subtypes. Blockage of Kv2.1 by SsmTx-I was not associated with significant alteration of steady-state activation, suggesting that SsmTx-I might act as a simple inhibitor or channel blocker rather than a gating modifier. Our study reported a specific Kv2.1-blocker from centipede venom and provided a basis for future investigations of SsmTx-I, for example on structure-function relationships, mechanism of action, and pharmacological potential.

  3. Increased cavernosal relaxation by Phoneutria nigriventer toxin, PnTx2-6, via activation at NO/cGMP signaling

    PubMed Central

    Nunes, K.P.; Wynne, B.M.; Cordeiro, M.N.; Borges, M.H.; Richardson, M; Leite, R.; DeLima, M.E.; Webb, R. C

    2011-01-01

    Erectile dysfunction mechanisms in diabetic patients are multifactorial and often lead to resistance to current therapy. Animal toxins have been used as pharmacological tools to study penile erection. Human accidents involving the venom of Phoneutria nigriventer spider are characterized by priapism. We hypothesize that PnTx2-6 potentiates cavernosal relaxation in diabetic mice by increasing cGMP. This effect is nNOS dependent. Cavernosal strips were contracted with phenylephrine (10−5 M) and relaxed by electrical field stimulation (EFS, 20V, 1–32 Hz) in the presence or absence of PnTx2-6 (10−8 M).Cavernosal strips from nNOS and eNOS knocaut (KO) mice, besides nNOS inhibitor (10−5M), were used to evaluate the role of this enzyme in the potentiation effect evoked by PnTx2-6. Tissue cGMP levels were determined after stimulation with PnTx2-6 in presence or absence of L-NAME (10−4M) and ω-conotoxin GVIA (10−6M), an N-type calcium channel inhibitor. Results showed PnTx2-6 enhanced cavernosal relaxation in diabetic mice (65%) and eNOS KO mice, but not in nNOS KO mice. The toxin effect in the cavernosal relaxation was abolished by nNOS inhibitor. cGMP levels are increased by PnTx2-6, however L-NAME abolished this enhancement as well as ω-conotoxin GVIA. We conclude PnTx2-6 facilitates penile relaxation in diabetic mice through a mechanism dependent on nNOS, probably via increasing NO/cGMP production. PMID:21975567

  4. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease

    PubMed Central

    Medici, Valentina; Shibata, Noreene M; Kharbanda, Kusum K; Islam, Mohammad S; Keen, Carl L; Kim, Kyoungmi; Tillman, Brittany; French, Samuel W; Halsted, Charles H; LaSalle, Janine M

    2014-01-01

    Maternal diet can affect fetal gene expression through epigenetic mechanisms. Wilson disease (WD), which is caused by autosomal recessive mutations in ATP7B encoding a biliary copper transporter, is characterized by excessive hepatic copper accumulation, but variability in disease severity. We tested the hypothesis that gestational supply of dietary methyl groups modifies fetal DNA methylation and expression of genes involved in methionine and lipid metabolism that are impaired prior to hepatic steatosis in the toxic milk (tx-j) mouse model of WD. Female C3H control and tx-j mice were fed control (choline 8 mmol/Kg of diet) or choline-supplemented (choline 36 mmol/Kg of diet) diets for 2 weeks throughout mating and pregnancy to gestation day 17. A second group of C3H females, half of which were used to cross foster tx-j pups, received the same diet treatments that extended during lactation to 21 d postpartum. Compared with C3H, fetal tx-j livers had significantly lower copper concentrations and significantly lower transcript levels of Cyclin D1 and genes related to methionine and lipid metabolism. Maternal choline supplementation prevented the transcriptional deficits in fetal tx-j liver for multiple genes related to cell growth and metabolism. Global DNA methylation was increased by 17% in tx-j fetal livers after maternal choline treatment (P < 0.05). Maternal dietary choline rescued the lower body weight of 21 d tx-j mice. Our results suggest that WD pathogenesis is modified by maternal in utero factors, including dietary choline. PMID:24220304

  5. Isolation and characterization of SsmTx-I, a Specific Kv2.1 blocker from the venom of the centipede Scolopendra Subspinipes Mutilans L. Koch.

    PubMed

    Chen, Minzhi; Li, Jing; Zhang, Fan; Liu, Zhonghua

    2014-03-01

    Scolopendra subspinipes mutilans, also known as Chinese red-headed centipede, is a venomous centipede from East Asia and Australasia. Venom from this animal has not been researched as thoroughly as venom from snakes, snails, scorpions, and spiders. In this study, we isolated and characterized SsmTx-I, a novel neurotoxin from the venom of S. subspinipes mutilans. SsmTx-I contains 36 residues with four cysteines forming two disulfide bonds. It had low sequence similarity (<10%) with other identified peptide toxins. By whole-cell recording, SsmTx-I significantly blocked voltage-gated K⁺ channels in dorsal root ganglion neurons with an IC₅₀ value of 200 nM, but it had no effect on voltage-gated Na⁺ channels. Among the nine K⁺ channel subtypes expressed in human embryonic kidney 293 cells, SsmTx-I selectively blocked the Kv2.1 current with an IC₅₀ value of 41.7 nM, but it had little effect on currents mediated by other K⁺ channel subtypes. Blockage of Kv2.1 by SsmTx-I was not associated with significant alteration of steady-state activation, suggesting that SsmTx-I might act as a simple inhibitor or channel blocker rather than a gating modifier. Our study reported a specific Kv2.1-blocker from centipede venom and provided a basis for future investigations of SsmTx-I, for example on structure-function relationships, mechanism of action, and pharmacological potential. PMID:24464516

  6. Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: solution structure of the potassium channel inhibitor HsTX1.

    PubMed Central

    Savarin, P.; Romi-Lebrun, R.; Zinn-Justin, S.; Lebrun, B.; Nakajima, T.; Gilquin, B.; Menez, A.

    1999-01-01

    We have determined the three-dimensional structure of the potassium channel inhibitor HsTX1, using nuclear magnetic resonance and molecular modeling. This protein belongs to the scorpion short toxin family, which essentially contains potassium channel blockers of 29 to 39 amino acids and three disulfide bridges. It is highly active on voltage-gated Kv1.3 potassium channels. Furthermore, it has the particularity to possess a fourth disulfide bridge. We show that HsTX1 has a fold similar to that of the three-disulfide-bridged toxins and conserves the hydrophobic core found in the scorpion short toxins. Thus, the fourth bridge has no influence on the global conformation of HsTX1. Most residues spatially analogous to those interacting with voltage-gated potassium channels in the three-disulfide-bridged toxins are conserved in HsTX1. Thus, we propose that Tyr21, Lys23, Met25, and Asn26 are involved in the biological activity of HsTX1. As an additional positively charged residue is always spatially close to the aromatic residue in toxins blocking the voltage-gated potassium channels, and as previous mutagenesis experiments have shown the critical role played by the C-terminus in HsTX1, we suggest that Arg33 is also important for the activity of the four disulfide-bridged toxin. Docking calculations confirm that, if Lys23 and Met25 interact with the GYGDMH motif of Kv1.3, Arg33 can contact Asp386 and, thus, play the role of the additional positively charged residue of the toxin functional site. This original configuration of the binding site of HsTX1 for Kv1.3, if confirmed experimentally, offers new structural possibilities for the construction of a molecule blocking the voltage-gated potassium channels. PMID:10631983

  7. Modeling regional salinization of the Ogallala aquifer, Southern High Plains, TX, USA

    USGS Publications Warehouse

    Mehta, S.; Fryar, A.E.; Brady, R.M.; Morin, R.H.

    2000-01-01

    Two extensive plumes (combined area > 1000 km2) have been delineated within the Ogallala aquifer in the Southern High Plains, TX, USA. Salinity varies within the plumes spatially and increases with depth; Cl ranges from 50 to >500 mg 1-1. Variable-density flow modeling using SUTRA has identified three broad regions of upward cross-formational flow from the underlying evaporite units. The upward discharge within the modeled plume area is in the range of 10-4-10-5 m3 day-1, and the TDS concentrations are typically >3000 mg 1-1. Regions of increased salinity, identified within the Whitehorse Group (evaporite unit) underlying the Ogallala aquifer, are controlled by the structure and thickness variations relative to the recharge areas. Distinct flow paths, on the order of tens of km to >100 km in length, and varying flow velocities indicate that the salinization of the Ogallala aquifer has been a slow, ongoing process and may represent circulation of waters recharged during Pleistocene or earlier times. On-going pumping has had negligible impact on the salinity distribution in the Ogallala aquifer, although simulations indicate that the velocity distribution in the underlying units may have been affected to depths of 150 m after 30 years of pumping. Because the distribution of saline ground water in this region of the Ogallala aquifer is heterogeneous, careful areal and vertical characterization is warranted prior to any well-field development. (C) 2000 Elsevier Science B.V.Two extensive plumes (combined area >1000 km2) have been delineated within the Ogallala aquifer in the Southern High Plains, TX, USA. Salinity varies within the plumes spatially and increases with depth; Cl ranges from 50 to >500 mg l-1. Variable-density flow modeling using SUTRA has identified three broad regions of upward cross-formational flow from the underlying evaporite units. The upward discharge within the modeled plume area is in the range of 10-4-10-5 m3 day-1, and the TDS concentrations

  8. Occupational exposure to benzene at the ExxonMobil refinery in Baytown, TX (1978-2006).

    PubMed

    Gaffney, Shannon H; Panko, Julie M; Unice, Ken M; Burns, Amanda M; Kreider, Marisa L; Gelatt, Richard H; Booher, Lindsay E; Paustenbach, Dennis J

    2011-01-01

    Although occupational benzene exposure of refinery workers has been studied for decades, no extensive analysis of historical industrial hygiene data has been performed focusing on airborne concentrations at specific refineries and tasks. This study characterizes benzene exposures at the ExxonMobil Baytown, TX, refinery from 1978 to 2006 to understand the variability in workers' exposures over time and during different job tasks. Exposures were grouped by operational status, job title, and tasks. More than 9000 industrial hygiene air samples were evaluated; approximately 4000 non-task (> 3 h) and 1000 task-related (< 3 h) personal samples were considered. Each sample was assigned to one of 27 job titles, 29 work areas, and 16 task bins (when applicable). Process technicians were sampled most frequently, resulting in the following mean benzene concentrations by area: hydrofiner (n=245, mean=1.3 p.p.m.), oil movements (n=286, mean=0.23 p.p.m.), reformer (n=575, mean=0.10 p.p.m.), tank farm (n=9, mean=0.65 p.p.m.), waste treatment (n=446, mean=0.13 p.p.m.), and other areas (n=460, mean=0.062 p.p.m.). The most frequently sampled task was sample collection (n=218, mean=0.40 p.p.m.). Job title and area did not significantly impact task-related exposures. Airborne concentrations were significantly lower after 1990 than before 1990. Results of this task-focused study may be useful when analyzing benzene exposures at other refineries.

  9. Linear B-cell epitopes in BthTX-1, BthTX-II and BthA-1, phospholipase A₂'s from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom.

    PubMed

    De-Simone, Salvatore G; Napoleão-Pego, Paloma; Teixeira-Pinto, Luiz A L; Santos, Jonathas D L; De-Simone, Thatiane S; Melgarejo, Anibal R; Aguiar, Aniesse S; Marchi-Salvador, Daniela P

    2013-09-01

    The benefits from treatment with antivenom sera are indubitable. However, the mechanism for toxin neutralization has not been completely elucidated. A mixture of anti-bothropic and anti-crotalic horse antivenom has been reported to be more effective in neutralizing the effects of Bothrops jararacussu snake venom than anti-bothropic antivenom alone. This study determined which regions in the three PLA₂s from B. jararacussu snake venom are bound by antibodies in tetravalent anti-bothropic and monovalent anti-crotalic commercial horse antivenom. Mapping experiments of BthTX-I, BthTX-II and BthA-I using two small libraries of 69 peptides each revealed six major IgG-binding epitopes that were recognized by both anti-bothropic and anti-crotalic horse antivenom. Two epitopes in BthTX-I were only recognized by the anti-bothropic horse antivenom, while anti-crotalic horse antivenom recognized four unique epitopes across the three PLA₂s. Our studies suggest that the harmful activities of the PLA₂s present in the venom of B. jararacussu are neutralized by the combinatorial treatment with both antivenom sera through their complementary binding sites, which provides a wide coverage on the PLA₂s. This is the first peptide microarray of PLA₂s from B. jararacussu snake venom to survey the performance of commercial horse antiophidic antivenom. Regions recognized by the protective antivenom sera are prime candidates for improved venom cocktails or a chimeric protein encoding the multiple epitopes to immunize animals as well as for designing future synthetic vaccines. PMID:23792452

  10. Equity and County College Financing.

    ERIC Educational Resources Information Center

    New Jersey State Commission on Financing Postsecondary Education, Trenton.

    An analysis by the Commission on Financial Postsecondary Education of the system by which New Jersey supports county colleges revealed disparities and inequities among the New Jersey counties in wealth and effort per full-time equivalent student, and current state financing practices that aggravate this problem. In response, alternative state…

  11. Frederick County Community Perception Survey.

    ERIC Educational Resources Information Center

    Frederick Community Coll., MD.

    In 1997, Frederick Community College (FCC) in Maryland conducted a telephone survey of a random sample of 466 Frederick County residents to identify their perceptions of the college. In particular, the survey examined Frederick County residents' image of FCC, level of awareness of services and programs offered by FCC, and the types of services…

  12. Topics for Lehigh County Seniors.

    ERIC Educational Resources Information Center

    Lehigh County Community Coll., Schnecksville, PA.

    Lehigh County Community College (Pennsylvania) and the Lehigh County Senior Citizens' Center collaborated on a project to assess the learning needs of the senior center's 1,600 members. A needs assessment completed by 68 center members and interviews of an additional 38 center members established that senior citizens preferred short-term workshops…

  13. Data Package for Calendar Year 2002 RCRA Groundwater Monitoring Wells at Single-Shell Tank Waste Management Area TX-TY

    SciTech Connect

    Horton, Duane G.

    2003-04-15

    Two new RCRA groundwater monitoring wells were installed at the single-shell tank farm at Waste Management Area TX-TY in October and November 2002. This document provides the information on drilling and construction of these wells. Two new Resource Conservation and Recovery Act (RCRA) groundwater monitoring wells were installed at the single-shell tank farm Waste Management Area (WMA) TX-TY in October and November 2002 in fulfillment of Tri-Party Agreement (Ecology et al. 1998) Milestone M-24-00N. The well names are 299-W14-19 and 299-W15-44; the corresponding well numbers are C3957 and C3956, respectively. Well 299-W14-19 is located east of the central part of the TX Tank Farm and is a downgradient well filling a gap in the monitoring network between wells 299-W14-14 and 299-W14-6. Well 299-W15-44 is located at the southwest corner of the TX Tank Farm in an area where groundwater flow has been artificially altered toward the southwest by the 200-ZP-1 Operable Unit pump-and-treat system. The well is in the cone of depression of the 200-ZP-1 extraction wells and is downgradient of WMA TX-TY. The locations of all wells in the WMA TX-TY monitoring network are shown on Figure 1. The original assessment monitoring plan for WMA TX-TY was issued in 1993 (Caggiano and Chou 1993). That plan was updated for the continued assessment at WMA TX-TY in 2001 (Hodges and Chou 2001). The updated plan provides justification for the new wells. The new wells were constructed to the specifications and requirements described in Washington Administrative Code (WAC) 173-160 and WAC 173-303, the updated assessment plan for WMA TX-TY (Hodges and Chou 2001), and the description of work for well drilling and construction. This document compiles information on the drilling and construction, geophysical logging, and sediment and groundwater sampling applicable to the installation of wells 299-W14-19 and 299-W15-44. The information on drilling and construction, well development, and pump

  14. Characterization of a Novel Alpha-Conotoxin TxID from Conus textile that Potently Blocks rat Alpha3beta4 Nicotinic Acetylcholine Receptors

    PubMed Central

    Luo, Sulan; Zhangsun, Dongting; Zhu, Xiaopeng; Wu, Yong; Hu, Yuanyan; Christensen, Sean; Harvey, Peta J.; Akcan, Muharrem; Craik, David J.; McIntosh, J. Michael

    2014-01-01

    The α3β4 nAChRs are implicated in pain sensation in the PNS and addiction to nicotine in the CNS. We identified an α-4/6-conotoxin (CTx) TxID from Conus textile. The new toxin consists of 15 amino acid residues with two disulfide bonds. TxID was synthesized using solid phase methods and the synthetic peptide was functionally tested on nAChRs heterologously expressed in Xenopus laevis oocytes. TxID blocked rat α3β4 nAChRs with a 12.5 nM IC50, which places it amongst the most potent α3β4 nAChR antagonists. TxID also blocked the closely related α6/α3β4 with a 94 nM IC50 but showed little activity on other nAChR subtypes. NMR analysis showed that two major structural isomers exist in solution, one of which adopts a regular α-CTx fold but with different surface charge distribution to other 4/6 family members. α-CTx TxID is a novel tool with which to probe the structure and function of α3β4 nAChRs. PMID:24200193

  15. Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1.

    PubMed

    Murray, Justin K; Biswas, Kaustav; Holder, J Ryan; Zou, Anruo; Ligutti, Joseph; Liu, Dong; Poppe, Leszek; Andrews, Kristin L; Lin, Fen-Fen; Meng, Shi-Yuan; Moyer, Bryan D; McDonough, Stefan I; Miranda, Les P

    2015-11-01

    Many efforts are underway to develop selective inhibitors of the voltage-gated sodium channel NaV1.7 as new analgesics. Thus far, however, in vitro selectivity has proved difficult for small molecules, and peptides generally lack appropriate pharmacokinetic properties. We previously identified the NaV1.7 inhibitory peptide GpTx-1 from tarantula venom and optimized its potency and selectivity via structure-guided analoging. To further understand GpTx-1 binding to NaV1.7, we have mapped the binding site to transmembrane segments 1-4 of the second pseudosubunit internal repeat (commonly referred to as Site 4) using NaV1.5/NaV1.7 chimeric protein constructs. We also report that select GpTx-1 amino acid residues apparently not contacting NaV1.7 can be derivatized with a hydrophilic polymer without adversely affecting peptide potency. Homodimerization of GpTx-1 with a bifunctional polyethylene glycol (PEG) linker resulted in a compound with increased potency and a significantly reduced off-rate, demonstrating the ability to modulate the function and properties of GpTx-1 by linking to additional molecules. PMID:26112439

  16. Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel.

    PubMed Central

    Bernard, C.; Legros, C.; Ferrat, G.; Bischoff, U.; Marquardt, A.; Pongs, O.; Darbon, H.

    2000-01-01

    HpTX2 is a toxin from the venom of Heteropoda venatoria spider that has been demonstrated to bind on Kv4.2 potassium channel. We have determined the solution structure of recombinant HpTX2 by use of conventional two-dimensional NMR techniques followed by distance-geometry and molecular dynamics. The calculated structure belongs to the Inhibitory Cystin Knot structural family that consists in a compact disulfide-bonded core, from which four loops emerge. A poorly defined two-stranded antiparallel beta-sheet (residues 20-23 and 25-28) is detected. Analysis of the electrostatic charge anisotropy allows us to propose a functional map of HpTX2 different from the one described for kappa-conotoxin PVIIA, but strongly related to the one of charybdotoxin. The orientation of the dipole moment of HpTX2 emerges through K27 which could therefore be the critical lysine residue. Close to this lysine are a second basic residue, R23, an aromatic cluster (F7, W25, W30) and an hydrophobic side chain (L24). The high density in aromatic side chains of the putative functional surface as well as the lack of an asparagine is proposed to be the structural basis of the specificity of HpTX2 toward Kv4.2 channel. PMID:11152117

  17. Hydrology of Polk County, Florida

    USGS Publications Warehouse

    Spechler, Rick M.; Kroening, Sharon E.

    2007-01-01

    Local water managers usually rely on information produced at the State and regional scale to make water-resource management decisions. Current assessments of hydrologic and water-quality conditions in Polk County, Florida, commonly end at the boundaries of two water management districts (South Florida Water Management District and the Southwest Florida Water Management District), which makes it difficult for managers to determine conditions throughout the county. The last comprehensive water-resources assessment of Polk County was published almost 40 years ago. To address the need for current countywide information, the U.S. Geological Survey began a 3?-year study in 2002 to update information about hydrologic and water-quality conditions in Polk County and identify changes that have occurred. Ground-water use in Polk County has decreased substantially since 1965. In 1965, total ground-water withdrawals in the county were about 350 million gallons per day. In 2002, withdrawals totaled about 285 million gallons per day, of which nearly 95 percent was from the Floridan aquifer system. Water-conservation practices mainly related to the phosphate-mining industry as well as the decrease in the number of mines in operation in Polk County have reduced total water use by about 65 million gallons per day since 1965. Polk County is underlain by three principal hydrogeologic units. The uppermost water-bearing unit is the surficial aquifer system, which is unconfined and composed primarily of clastic deposits. The surficial aquifer system is underlain by the intermediate confining unit, which grades into the intermediate aquifer system and consists of up to two water-bearing zones composed of interbedded clastic and carbonate rocks. The lowermost hydrogeologic unit is the Floridan aquifer system. The Floridan aquifer system, a thick sequence of permeable limestone and dolostone, consists of the Upper Floridan aquifer, a middle semiconfining unit, a middle confining unit, and

  18. 75 FR 36348 - Opportunity for Designation in the Amarillo, TX; Cairo, IL; and State of North Carolina Areas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Carolina) official agencies will end on September 30, 2010. In the March 31, 2010, Federal Register (71 FR... Donley County; the southern Donley and Armstrong County lines west to Prairie Dog Town Fork of the Red River; Prairie Dog Town Fork of the Red River northwest to State Route 217; State Route 217 west to...

  19. Modeling erosion and sediment control practices in RUSLE 2.0: A management approach for natural gas well sites in Denton County, TX, USA

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sediment yields from natural gas well sites can be substantial and warrant consideration of appropriate erosion and sediment control Best Management Practices(BMPs). Version 2 of the Revised Universal Soil Loss Equation (RUSLE 2.0) was used to predict sediment yields and evaluate the efficiency of ...

  20. 76 FR 68188 - Valero Refining-Texas, L.P. v. Port of Corpus Christi Authority of Nueces County, TX; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... are excessive and not reasonably related to the value of services rendered to Complainant.'' Further..., affidavits, depositions, or other documents or that the nature of the matter in issue is such that an...

  1. A Large-N Mixed Sensor Active + Passive Seismic Array near Sweetwater, TX

    NASA Astrophysics Data System (ADS)

    Barklage, M.; Hollis, D.; Gridley, J. M.; Woodward, R.; Spriggs, N.

    2014-12-01

    A collaborative high-density seismic survey using broadband and short period seismic sensors was conducted March 7 - April 30, 2014 near Sweetwater, TX. The objective of the survey was to use a combination of controlled source shot slices and passive seismic recordings recorded by multiple types of sensors with different bandwidths and sensitivities to image the subsurface. The broadband component of the survey consisted of 25 continuously recording seismic stations comprised of 20 Trillium Compact Posthole sensors from Nanometrics and 5 Polar Trillium 120PHQs from the IRIS/PASSCAL Instrument Center (PIC). The broadband stations also utilized 25 Centaur digitizers from Nanometrics as well as 25 polar quick deploy enclosures from the PIC. The broadband array was designed to maximize horizontal traveling seismic energy for surface wave analysis over the primary target area with sufficient offset for imaging objectives at depth. The short period component of the survey consisted of 2639 receiver locations using Zland nodes from NodalSeismic. The nodes are further divided into 3 sub-arrays: 1) outlier array 2) active source array 3) backbone array. The outlier array consisted of 25 continuously recording nodes distributed around the edge of the survey at a distance of ~5 km from the survey boundary, and provided valuable constraints to passive data analysis techniques at the edge of the survey boundary. The active source patch consisted of densely spaced nodes that were designed to record signals from a Vibroseis source truck for active source reflection processing and imaging. The backbone array consisted of 292 nodes that covered the entirety of the survey area to maximize the value of the passive data analysis. By utilizing continuous recording and smartly designed arrays for measuring local and regional earthquakes we can incorporate velocity information derived from passive data analysis into the active source processing workflow to produce a superior subsurface

  2. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  3. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  4. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  5. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  6. 32 CFR 1602.10 - County.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false County. 1602.10 Section 1602.10 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.10 County. The word county includes, where applicable, counties, independent cities, and similar...

  7. CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles.

    PubMed

    Almeida, J R; Lancellotti, M; Soares, A M; Calderon, L A; Ramírez, D; González, W; Marangoni, S; Da Silva, S L

    2016-09-15

    Snake venoms are rich and intriguing sources of biologically-active molecules that act on target cells, modulating a diversity of physiological functions and presenting promising pharmacological applications. Lys49 phospholipase A2 is one of the multifunctional proteins present in these complex secretions and, although catalytically inactive, has a variety of biological activities, including cytotoxic, antibacterial, inflammatory, antifungal activities. Herein, a Lys49 phospholipase A2, denominated CoaTx-II from Crotalus oreganus abyssus, was purified and structurally and pharmacologically characterized. CoaTx-II was isolated with a high degree of purity by a combination of two chromatographic steps; molecular exclusion and reversed-phase high performance liquid chromatography. This toxin is dimeric with a mass of 13868.2 Da (monomeric form), as determined by mass spectrometry. CoaTx-II is rich in Arg and Lys residues and displays high identity with other Lys49 PLA2 homologues, which have high isoelectric points. The structural model of dimeric CoaTx-II shows that the toxin is non-covalently stabilized. Despite its enzymatic inactivity, in vivo CoaTx-II caused local muscular damage, characterized by increased plasma creatine kinase and confirmed by histological alterations, in addition to an inflammatory activity, as demonstrated by mice paw edema induction and pro-inflammatory cytokine IL-6 elevation. CoaTx-II also presents antibacterial activity against gram negative (Pseudomonas aeruginosa 31NM, Escherichia coli ATCC 25922) and positive (Staphyloccocus aureus BEC9393 and Rib1) bacteria. Therefore, data show that this newly purified toxin plays a central role in mediating the degenerative events associated with envenomation, in addition to demonstrating antibacterial properties, with potential for use in the development of strategies for antivenom therapy and combating antibiotic-resistant bacteria. PMID:27530662

  8. CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles.

    PubMed

    Almeida, J R; Lancellotti, M; Soares, A M; Calderon, L A; Ramírez, D; González, W; Marangoni, S; Da Silva, S L

    2016-09-15

    Snake venoms are rich and intriguing sources of biologically-active molecules that act on target cells, modulating a diversity of physiological functions and presenting promising pharmacological applications. Lys49 phospholipase A2 is one of the multifunctional proteins present in these complex secretions and, although catalytically inactive, has a variety of biological activities, including cytotoxic, antibacterial, inflammatory, antifungal activities. Herein, a Lys49 phospholipase A2, denominated CoaTx-II from Crotalus oreganus abyssus, was purified and structurally and pharmacologically characterized. CoaTx-II was isolated with a high degree of purity by a combination of two chromatographic steps; molecular exclusion and reversed-phase high performance liquid chromatography. This toxin is dimeric with a mass of 13868.2 Da (monomeric form), as determined by mass spectrometry. CoaTx-II is rich in Arg and Lys residues and displays high identity with other Lys49 PLA2 homologues, which have high isoelectric points. The structural model of dimeric CoaTx-II shows that the toxin is non-covalently stabilized. Despite its enzymatic inactivity, in vivo CoaTx-II caused local muscular damage, characterized by increased plasma creatine kinase and confirmed by histological alterations, in addition to an inflammatory activity, as demonstrated by mice paw edema induction and pro-inflammatory cytokine IL-6 elevation. CoaTx-II also presents antibacterial activity against gram negative (Pseudomonas aeruginosa 31NM, Escherichia coli ATCC 25922) and positive (Staphyloccocus aureus BEC9393 and Rib1) bacteria. Therefore, data show that this newly purified toxin plays a central role in mediating the degenerative events associated with envenomation, in addition to demonstrating antibacterial properties, with potential for use in the development of strategies for antivenom therapy and combating antibiotic-resistant bacteria.

  9. Search for dust shells in W Ser binaries and similar object: RX Cassiopeiae and TX Ursae Majoris

    NASA Astrophysics Data System (ADS)

    Taranova, O. G.; Shenavrin, V. I.

    1997-11-01

    The results of UBVRJHKLM photometry for a strongly interacting W Ser binary (RX Cas) and an Algol-type system (TX UMa) are analyzed. The spectral classification of the stellar components of the binaries is made, and the sources of excess emission at wavelengths lambda 3.5 and 5 m are analyzed. The weak excess at lambda 5 microns are analyzed. The weak excess at lambda 5 microns in TX UMa is shown to be associated with the emission of an ionized shell with a volume emission measure ~ 2.7 x 10^57 cm^-3. The excess at lambda 3.5 and 5 microns in RX Cas is attributable to the emission of an optically thin circumstellar dust shell with a grain temperature ~ 600-700 K. The luminosity is ~ 3 x 10^33 erg s^-1, the radius of the dust shell is ~ 4.6 x 10^14 cm, the optical depth at lambda 1.25 microns is ~10^-3, and the mass is ~10^23 g.

  10. Growth of Pseudomonas sp. TX1 on a wide range of octylphenol polyethoxylate concentrations and the formation of dicarboxylated metabolites.

    PubMed

    Lin, Yi-Wen; Guo, Gia-Luen; Hsieh, Hsiao-Cheng; Huang, Shir-Ly

    2010-04-01

    Pseudomonas sp. TX1, is able to use octylphenol polyethoxylates (OPEO(n), or Triton X-100; average n = 9.5) as a sole carbon source. It can grow on 0.05-20% of OPEO(n) with a specific growth rate of 0.34-0.44 h(-1). High-performance liquid chromatography-mass spectrometer analysis of OPEO(n) degraded metabolites revealed that strain TX1 was able to shorten the ethoxylate chain and produce octylphenol (OP). Furthermore, formation of the short carboxylate metabolites, such as carboxyoctylphenol polyethoxylates (COPEO(n), n = 2, 3) and carboxyoctylphenol polyethoxycarboxylates (COPEC(n), n = 2, 3) began at the log stage, while octylphenol polyethoxycarboxylates (OPEC(n), n = 1-3) was formed at the stationary phase. All the short-ethoxylated metabolites, OPEO(n), OPEC(n), COPEO(n), and COPEC(n), accumulated when the cells were in the stationary phase. This study is the first to demonstrate the formation of COPEO(n) and COPEC(n) from OPEO(n) by an aerobic bacterium. PMID:20044249

  11. SURFACE GEOPHYSICAL EXPLORATION OF TX-TY TANK FARMS AT THE HANFORD SITE RESULTS OF BACKGROUND CHARACTERIZATION WITH GROUND PENETRATING RADAR

    SciTech Connect

    MYERS DA; CUBBAGE R; BRAUCHLA R; O'BRIEN G

    2008-07-24

    Ground penetrating radar surveys of the TX and TY tank farms were performed to identify existing infrastructure in the near surface environment. These surveys were designed to provide background information supporting Surface-to-Surface and Well-to-Well resistivity surveys of Waste Management Area TX-TY. The objective of the preliminary investigation was to collect background characterization information with GPR to understand the spatial distribution of metallic objects that could potentially interfere with the results from high resolution resistivity{trademark} surveys. The results of the background characterization confirm the existence of documented infrastructure, as well as highlight locations of possible additional undocumented subsurface metallic objects.

  12. Energy Improvements in Barnstable County

    SciTech Connect

    2003-09-01

    A fact sheet that describes Barnstable County, Massachusetts, effort to improve energy efficiency through a public appliance trade-in program, installation of compact fluorescent light bulbs in public buildings, and public energy education.

  13. Geothermal development plan: Yuma county

    SciTech Connect

    White, D.H.

    1981-01-01

    One hot spring and 33 wells drilled in the county discharge water at temperatures sufficient for direct-use geothermal applications such as process heat and space heating and cooling. Currently, one industry within the county has been identified which may be able to use geothermal energy for its process heat requirements. Also, a computer simulation model was used to predict geothermal energy on line as a function of time under both private and city-owned utility development of the resource.

  14. Geothermal Development Plan: Pima County

    SciTech Connect

    White, D.H.

    1981-01-01

    Pima County is located entirely within the Basin and Range physiographic province in which geothermal resources are known to occur. Continued growth as indicated by such factors as population growth, employment and income will require large amounts of energy. It is believed that geothermal energy could provide some of the energy that will be needed. Potential users of geothermal energy within the county are identified.

  15. Dispersion Modeling of Inert Particulate Matter in the El Paso, TX- Cd. Juarez, MX Region

    NASA Astrophysics Data System (ADS)

    Pearson, R.; Fitzgerald, R.

    2005-05-01

    The El Paso, TX-Cd. Juarez, MX region is subject to the emission of inert particulate matter (PM) into the atmosphere, from a variety of sources. The impact of these emissions has been studied extensively in for regulatory compliance in the area of health effects, air quality and visibility. Little work has been done to study the fate and transport of the particulate matter within the region. The Environmental Physics Group at The University of Texas at El Paso has recently applied the SARMAP Air Quality Model (SAQM) to model the dispersion of inert particulate matter in the region. The meteorological data for the SAQM was created with the Penn State/NCAR meteorological modeling system, version 5 (MM5). The SAQM was used to simulate three common occurrences for large particulate emission and concentration. The first was times of heavy traffic volume at the international bridges which cause large numbers of cars to sit, with engines running, for extended periods of time. The second was moderate to high wind events that cause large amounts of coarse particulate matter to become entrained in the atmosphere and transported into and around the region. The third is a temperature inversion which traps the particulate matter at the surface during morning rush hour. The initial conditions for particulate matter, for the two cases involving mobile emissions, were derived from the 1999 version 3 national emissions inventory (NEI) mobile, on-road data from the EPA. Output from the MM5 was used to as the meteorological driver for the SAQM. The MM5 was initialized with data from the NCAR reanalysis project. Meteorological data collected in the region bye the Texas Commission on Environmental Quality (TCEQ) and the EPA was used for Four Dimensional Data Assimilation. The MM5 was nudged with gridded, surface and observational data. Statistical analysis was done on the MM5 for the variables, wind speed, wind direction, temperature and mixing ratio. The statistics performed included

  16. A Detailed Process Based Evaluation of Photochemical Air Quality Model Simulations of Houston, TX

    NASA Astrophysics Data System (ADS)

    Vizuete, W.; Kioumourtzoglou, M.; Jeffries, H.

    2006-12-01

    This work will present a process based evaluation of several modeling attempts of the Houston, TX non- attainment area. These modeling attempts include efforts by the Texas state agency, private consultants, and several Universities, resulting in multiple simulations of the same modeling episode and domain. These simulations were performed with the Comprehensive Air quality Model with extensions (CAMx) under a variety of meteorological and emission inputs. Through an initial comparison of model and ambient data the model underpredicts ozone concentrations in nearly every modeling attempt. This observation held true even when a large artificial imputation of ozone precursors, specifically ethylene and propylene, were added to some modeling simulations. An examination of the level of agreement between model predictions and observations of ozone concentrations, however, is not a sufficient method to understand the reasons for this inaccuracy. This is especially true in a non-linear feedback system such as ozone formation where the same ozone prediction can be reached through the combination of various physical and chemical processess. A more meaningful method of model analysis that focuses on theses processes lead to the development of the pyPA (Process Analysis in python) tool. This tool provides a framework for an in-depth analysis of modeling data by quantifying radical budgets, source and fate of ozone precursors, and the physical processes that effect each species. The pyPA tool was used to analyze each simulation scenario of the Houston airshed allowing for a process based intercomparison. An analysis of the radical budget revealed a deficient source of organically derived free radicals (HO2 and OH.) in the modeling system. Atmospheric reactivity and consequently ozone formation was limited by lack of radical sources; regardless of the levels of ethylene or propylene introduced into the system. NOx overpredictions by a factor of two further depleted the limited

  17. Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice.

    PubMed

    Tanaka, Ken-Ichiro; Sekino, Shota; Ikegami, Megumi; Ikeda, Hiroko; Kamei, Junzo

    2015-01-01

    The present study investigated the effects of intrathecal administration of ProTx-II (tarantula venom peptide) and A803467 (5-[4-chloro-phenyl]-furan-2-carboxylic acid [3,5-dimethoxy-phenyl]-amide), selective Nav1.7 and Nav1.8 antagonists, respectively, on thermal hyperalgesia in a painful diabetic neuropathy model of mice. Intrathecal administration of ProTx-II at doses from 0.04 to 4 ng to diabetic mice dose-dependently and significantly increased the tail-flick latency. Intrathecal administration of A803467 at doses from 10 to 100 ng to diabetic mice also dose-dependently and significantly increased the tail-flick latency. However, intrathecal administration of either ProTx-II (4 ng) or A803467 (100 ng) had no effect on the tail-flick latency in nondiabetic mice. The expression of either the Nav1.7 or Nav1.8 sodium channel protein in the dorsal root ganglion in diabetic mice was not different from that in nondiabetic mice. The present results suggest that ProTx-II and A803467, highly selective blockers of Nav1.7 and Nav1.8 sodium channels, respectively, in the spinal cord, can have antihyperalgesic effects in diabetic mice. PMID:27186141

  18. Antihyperalgesic effects of ProTx-II, a Nav1.7 antagonist, and A803467, a Nav1.8 antagonist, in diabetic mice

    PubMed Central

    Tanaka, Ken-ichiro; Sekino, Shota; Ikegami, Megumi; Ikeda, Hiroko; Kamei, Junzo

    2015-01-01

    The present study investigated the effects of intrathecal administration of ProTx-II (tarantula venom peptide) and A803467 (5-[4-chloro-phenyl]-furan-2-carboxylic acid [3,5-dimethoxy-phenyl]-amide), selective Nav1.7 and Nav1.8 antagonists, respectively, on thermal hyperalgesia in a painful diabetic neuropathy model of mice. Intrathecal administration of ProTx-II at doses from 0.04 to 4 ng to diabetic mice dose-dependently and significantly increased the tail-flick latency. Intrathecal administration of A803467 at doses from 10 to 100 ng to diabetic mice also dose-dependently and significantly increased the tail-flick latency. However, intrathecal administration of either ProTx-II (4 ng) or A803467 (100 ng) had no effect on the tail-flick latency in nondiabetic mice. The expression of either the Nav1.7 or Nav1.8 sodium channel protein in the dorsal root ganglion in diabetic mice was not different from that in nondiabetic mice. The present results suggest that ProTx-II and A803467, highly selective blockers of Nav1.7 and Nav1.8 sodium channels, respectively, in the spinal cord, can have antihyperalgesic effects in diabetic mice. PMID:27186141

  19. Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA.

    PubMed

    Rivera-Torres, Iván O; Jin, Tony B; Cadene, Martine; Chait, Brian T; Poget, Sébastien F

    2016-01-01

    Due to their central role in essential physiological processes, potassium channels are common targets for animal toxins. These toxins in turn are of great value as tools for studying channel function and as lead compounds for drug development. Here, we used a direct toxin pull-down assay with immobilised KcsA potassium channel to isolate a novel KcsA-binding toxin (called Tx7335) from eastern green mamba snake (Dendroaspis angusticeps) venom. Sequencing of the toxin by Edman degradation and mass spectrometry revealed a 63 amino acid residue peptide with 4 disulphide bonds that belongs to the three-finger toxin family, but with a unique modification of its disulphide-bridge scaffold. The toxin induces a dose-dependent increase in both open probabilities and mean open times on KcsA in artificial bilayers. Thus, it unexpectedly behaves as a channel activator rather than an inhibitor. A charybdotoxin-sensitive mutant of KcsA exhibits similar susceptibility to Tx7335 as wild-type, indicating that the binding site for Tx7335 is distinct from that of canonical pore-blocker toxins. Based on the extracellular location of the toxin binding site (far away from the intracellular pH gate), we propose that Tx7335 increases potassium flow through KcsA by allosterically reducing inactivation of the channel.

  20. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Webb Consolidated Independent School District in Bruni, TX - Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the arsenic removal treatment technology demonstration project at the Webb Consolidated Independent School District (Webb CISD) in Bruni, TX. The main objective of the project was to evaluate the effect...

  1. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Alvin, TX, Six-Month Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the first six months of the EPA arsenic removal technology demonstration project at the Oak Manor Municipal Utility District (MUD) facility at Alvin, TX. The main objective of the project is to evaluate...

  2. ARSENIC REMOVAL FROM DRINKING WATER BY ADSORPTIVE MEDIA U.S. EPA DEMONSTRATION PROJECT AT BRUNI, TX, SIX-MONTH EVALUATION REPORT

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the first six months of the arsenic removal treatment technology demonstration project at the Webb Consolidated Independent School District (Webb CISD) site at Bruni, TX. The main objective of the projec...

  3. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Wellman, TX, Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the arsenic removal treatment technology demonstration project in the City of Wellman, TX. The main objective of the project was to evaluate the effectiveness of AdEdge Technologies’ AD-33 media in remo...

  4. Arsenic Removal from Drinking Water by Adsorptive Media. U.S. EPA Demonstration Project at Oak Manor Municipal Utility District at Alvin, TX. Final Performance Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained for the EPA arsenic removal technology demonstration project at the Oak Manor Municipal Utility District (MUD) facility in Alvin, TX. The objectives of the project were to evaluate 1) the effectiveness of a ...

  5. Arsenic Removal from Drinking Water by Adsorptive Media U.S. EPA Demonstration Project at Wellman, TX, Six-Month Evaluation Report

    EPA Science Inventory

    This report documents the activities performed and the results obtained from the first six months of the arsenic removal treatment technology demonstration project in the City of Wellman, TX. The main objective of the project was to evaluate the effectiveness of AdEdge Technolog...

  6. Registration of high-oleic peanut germplasm line ARSOK-S1 (TX996784) with enhanced resistance to Sclerotinia blight and pod rot

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The high oleic Spanish peanut (Arachis hypogaea L. subsp. fastigiata var. vulgaris) germplasm line ARSOK-S1 was developed cooperatively between the USDA Agricultural Research Service, Texas AgriLife Research, and Oklahoma State University, and was released in 2013. ARSOK-S1 (tested early as TX99678...

  7. Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA

    PubMed Central

    Rivera-Torres, Iván O.; Jin, Tony B.; Cadene, Martine; Chait, Brian T.; Poget, Sébastien F.

    2016-01-01

    Due to their central role in essential physiological processes, potassium channels are common targets for animal toxins. These toxins in turn are of great value as tools for studying channel function and as lead compounds for drug development. Here, we used a direct toxin pull-down assay with immobilised KcsA potassium channel to isolate a novel KcsA-binding toxin (called Tx7335) from eastern green mamba snake (Dendroaspis angusticeps) venom. Sequencing of the toxin by Edman degradation and mass spectrometry revealed a 63 amino acid residue peptide with 4 disulphide bonds that belongs to the three-finger toxin family, but with a unique modification of its disulphide-bridge scaffold. The toxin induces a dose-dependent increase in both open probabilities and mean open times on KcsA in artificial bilayers. Thus, it unexpectedly behaves as a channel activator rather than an inhibitor. A charybdotoxin-sensitive mutant of KcsA exhibits similar susceptibility to Tx7335 as wild-type, indicating that the binding site for Tx7335 is distinct from that of canonical pore-blocker toxins. Based on the extracellular location of the toxin binding site (far away from the intracellular pH gate), we propose that Tx7335 increases potassium flow through KcsA by allosterically reducing inactivation of the channel. PMID:27044983

  8. Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA.

    PubMed

    Rivera-Torres, Iván O; Jin, Tony B; Cadene, Martine; Chait, Brian T; Poget, Sébastien F

    2016-01-01

    Due to their central role in essential physiological processes, potassium channels are common targets for animal toxins. These toxins in turn are of great value as tools for studying channel function and as lead compounds for drug development. Here, we used a direct toxin pull-down assay with immobilised KcsA potassium channel to isolate a novel KcsA-binding toxin (called Tx7335) from eastern green mamba snake (Dendroaspis angusticeps) venom. Sequencing of the toxin by Edman degradation and mass spectrometry revealed a 63 amino acid residue peptide with 4 disulphide bonds that belongs to the three-finger toxin family, but with a unique modification of its disulphide-bridge scaffold. The toxin induces a dose-dependent increase in both open probabilities and mean open times on KcsA in artificial bilayers. Thus, it unexpectedly behaves as a channel activator rather than an inhibitor. A charybdotoxin-sensitive mutant of KcsA exhibits similar susceptibility to Tx7335 as wild-type, indicating that the binding site for Tx7335 is distinct from that of canonical pore-blocker toxins. Based on the extracellular location of the toxin binding site (far away from the intracellular pH gate), we propose that Tx7335 increases potassium flow through KcsA by allosterically reducing inactivation of the channel. PMID:27044983

  9. 75 FR 43564 - TA-W-71,483, Continental Airlines, Inc., Reservations Division, Houston, TX; TA-W-71,483A...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... Register on May 20, 2010 (75 FR 28301). Workers of Continental Airlines, Inc., Reservations Division are... Employment and Training Administration TA-W-71,483, Continental Airlines, Inc., Reservations Division, Houston, TX; TA-W-71,483A, Continental Airlines, Inc., Reservations Division, Tampa, FL;...

  10. Somerset County Flood Information System

    USGS Publications Warehouse

    Hoppe, Heidi L.

    2007-01-01

    The timely warning of a flood is crucial to the protection of lives and property. One has only to recall the floods of August 2, 1973, September 16 and 17, 1999, and April 16, 2007, in Somerset County, New Jersey, in which lives were lost and major property damage occurred, to realize how costly, especially in terms of human life, an unexpected flood can be. Accurate forecasts and warnings cannot be made, however, without detailed information about precipitation and streamflow in the drainage basin. Since the mid 1960's, the National Weather Service (NWS) has been able to forecast flooding on larger streams in Somerset County, such as the Raritan and Millstone Rivers. Flooding on smaller streams in urban areas was more difficult to predict. In response to this problem the NWS, in cooperation with the Green Brook Flood Control Commission, installed a precipitation gage in North Plainfield, and two flash-flood alarms, one on Green Brook at Seeley Mills and one on Stony Brook at Watchung, in the early 1970's. In 1978, New Jersey's first countywide flood-warning system was installed by the U.S. Geological Survey (USGS) in Somerset County. This system consisted of a network of eight stage and discharge gages equipped with precipitation gages linked by telephone telemetry and eight auxiliary precipitation gages. The gages were installed throughout the county to collect precipitation and runoff data that could be used to improve flood-monitoring capabilities and flood-frequency estimates. Recognizing the need for more detailed hydrologic information for Somerset County, the USGS, in cooperation with Somerset County, designed and installed the Somerset County Flood Information System (SCFIS) in 1990. This system is part of a statewide network of stream gages, precipitation gages, weather stations, and tide gages that collect data in real time. The data provided by the SCFIS improve the flood forecasting ability of the NWS and aid Somerset County and municipal agencies in

  11. Geothermal development plan: Yuma County

    SciTech Connect

    White, D.H.; Goldstone, L.A.

    1982-08-01

    The Yuma County Area Development Plan evaluated the county-wide market potential for utilizing geothermal energy. The study identified four potential geothermal resource areas with temperatures less than 90/sup 0/C (194/sup 0/F), and in addition, two areas are inferred to contain geothermal resources with intermediate (90/sup 0/C to 150/sup 0/C, 194/sup 0/F to 300/sup 0/F) temperature potential. The resource areas are isolated, although one resource area is located near Yuma, Arizona. One resource site is inferred to contain a hot dry rock resource. Anticipated population growth in the county is expected to be 2 percent per year over the next 40 years. The primary employment sector is agriculture, though some light industry is located in the county. Water supplies are found to be adequate to support future growth without advese affect on agriculture. Six firms were found in Yuma County which may be able to utilize geothermal energy for process heat needs. In addition, several agricultural processors were found, concentrated in citrus processing and livestock raising. Geothermal energy utilization projections suggest that by the year 2000, geothermal energy may economically provide the energy equivalent of 53,000 barrels of oil per year to the industrial sector if developed privately. Geothermal utilization projections increase to 132,000 barrels of oil per year by 2000 if a municipal utility developed the resource.

  12. Alternating magnetic anisotropy of Li2(Li1–xTx)N (T = Mn, Fe, Co, and Ni)

    DOE PAGES

    Jesche, A.; Ke, L.; Jacobs, J. L.; Harmon, B.; Houk, R. S.; Canfield, P. C.

    2015-05-11

    Substantial amounts of the transition metals Mn, Fe, Co, and Ni can be substituted for Li in single crystalline Li2(Li1–xTx)N. Isothermal and temperature-dependent magnetization measurements reveal local magnetic moments with magnitudes significantly exceeding the spin-only value. The additional contributions stem from unquenched orbital moments that lead to rare-earth-like behavior of the magnetic properties. Accordingly, extremely large magnetic anisotropies have been found. Most notably, the magnetic anisotropy alternates as easy plane→easy axis→easy plane→easy axis when progressing from T = Mn → Fe → Co → Ni. This behavior can be understood based on a perturbation approach in an analytical, single-ion model.more » As a result, the calculated magnetic anisotropies show surprisingly good agreement with the experiment and capture the basic features observed for the different transition metals.« less

  13. Interaction of gums (guar, carboxymethylhydroxypropyl guar, diutan, and xanthan) with surfactants (DTAB, CTAB, and TX-100) in aqueous medium.

    PubMed

    Mukherjee, Indrajyoti; Sarkar, Diptabhas; Moulik, Satya P

    2010-12-01

    The interaction of surfactants dodecyltrimethylammonium bromide (DTAB), cetyltrimethylammonium bromide (CTAB), and p-tert-octylphenoxypolyoxyethylene (9.5) ether (TX-100) with guar (Gr), carboxymethylhydroxypropyl guar (CMHPG), diutan (Dn), and xanthan (Xn) gums has been studied employing conductometry, tensiometry, microcalorimetry, viscometry, and atomic force microscopy (AFM) techniques. Both weak and strong interactions were observed. CTAB interacted stronger than DTAB with the gums. The surfactant-gum interaction process was enhanced by the presence of borate ions in the solution; the borate ion itself also manifested interaction with the surfactants comparable with that of water-soluble polymers polyvinyl alcohol, polyoxyethylene, and so forth. Viscometric results supported configurational changes of the gum molecules by interaction with surfactants. The geometry of the pure gums and their CTAB interacted products in the dried states was ascertained from AFM measurements; spherical and prolate shapes were observed for pure gums, and distorted states were observed for their surfactant complexed species. Detailed topological features of these entities were ascertained.

  14. 2004 Initial Assessments for the T and TX TY Tank Farm Field Investigation Report (FIR): Numerical Simulations

    SciTech Connect

    Zhang, Z. F.; Freedman, Vicky L.; Waichler, Scott R.

    2004-09-24

    In support of CH2M HILL Hanford Group, Inc.’s (CHG) preparation of a Field Investigative Report (FIR) for the Hanford Site Single-Shell Tank Waste Management Area (WMA) T and TX-TY, a suite of numerical simulations of flow and solute transport was executed using the STOMP code to predict the performance of surface barriers for reducing long-term risks from potential groundwater contamination at the T and TX-TY WMA. The scope and parametric data for these simulations were defined by a modeling data package provided by CHG. This report documents the simulation involving 2-D cross sections through the T Tank and the TX-TY Tank Farm. Eight cases were carried out for the cross sections to simulate the effects of interim barrier, water line leak, inventory distribution, and surface recharge on water flow and the transport of long-lived radionuclides (i.e., technecium-99 and uranium) and chemicals (i.e., nitrate and chromium For simulations with barriers, it is assumed that an interim barrier is in place by the year 2010. It was also assumed that, for all simulations, as part of tank farm closure, a closure barrier was in place by the year 2040. The modeling considers the estimated inventories of contaminants within the vadose zone and calculates the associated risk. It assumes that no tanks will leak in the future. Initial conditions for contaminant concentration are provided as part of inventory estimates for uranium, technetium-99, nitrate, and chromium. For moisture flow modeling, Neumann boundary conditions are prescribed at the surface with the flux equal to the recharge rate estimate. For transport modeling, a zero flux boundary is prescribed at the surface for uranium, technetium-99, nitrate, and chromium. The western and eastern boundaries are assigned no-flux boundaries for both flow and transport. The water table boundary is prescribed by water table elevations and the unconfined aquifer hydraulic gradient. No-flux boundaries are used for the lower boundary

  15. Results of Phase I groundwater quality assessment for single-shell tank waste management areas T and TX-TY at the Hanford Site

    SciTech Connect

    Hodges, F.N.

    1998-01-01

    Pacific Northwest National Laboratory (PNNL) conducted a Phase I, Resource Conservation and Recovery Act of 1976 (RCRA) groundwater quality assessment for the Richland Field Office of the U.S. Department of Energy (DOE-RL) under the requirements of the Federal Facility Compliance Agreement. The purpose of the investigation was to determine if the Single-Shell Tank Waste Management Areas (WMAs) T and TX-TY have impacted groundwater quality. Waste Management Areas T and TX-TY, located in the northern part of the 200 West Area of the Hanford Site, contain the 241-T, 241-TX, and 241-TY tank farms and ancillary waste systems. These two units are regulated under RCRA interim-status regulations (under 40 CFR 265.93) and were placed in assessment groundwater monitoring because of elevated specific conductance in downgradient wells. Anomalous concentrations of technetium-99, chromium, nitrate, iodine-129, and cobalt-60 also were observed in some downgradient wells. Phase I assessment, allowed under 40 CFR 265, provides the owner-operator of a facility with the opportunity to show that the observed contamination has a source other than the regulated unit. For this Phase I assessment, PNNL evaluated available information on groundwater chemistry and past waste management practices in the vicinity of WMAs T and TX-TY. Background contaminant concentrations in the vicinity of WMAs T and TX-TY are the result of several overlapping contaminant plumes resulting from past-practice waste disposal operations. This background has been used as baseline for determining potential WMA impacts on groundwater.

  16. The effect of water on the microstructure of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/benzene ionic liquid microemulsions.

    PubMed

    Gao, Yan'an; Li, Na; Zheng, Liqiang; Zhao, Xueyan; Zhang, Jin; Cao, Quan; Zhao, Mingwei; Li, Zhen; Zhang, Gaoyong

    2007-01-01

    The ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]) forms nonaqueous microemulsions with benzene with the aid of nonionic surfactant TX-100. The phase diagram of the ternary system was prepared, and the microstructures of the microemulsion were recognized. On the basis of the phase diagram, a series of ionic liquid-in-oil (IL/O) microemulsions were chosen and characterized by dynamic light scattering (DLS), which shows a similar swelling behavior to typical water-in-oil (W/O) microemulsions. The existence of IL pools in the IL/O microemulsion was confirmed by UV/Vis spectroscopic analysis with CoCl2 and methylene blue (MB) as the absorption probes. A constant polarity of the IL pool is observed, even if small amounts of water are added to the microemulsion, thus suggesting that the water molecules are solubilized in the polar outer shell of the microemulsion, as confirmed by FTIR spectra. 1H NMR spectroscopic analysis shows that these water molecules interact with the electronegative oxygen atoms of the oxyethylene (OE) units of TX-100 through hydrogen-bonding interactions, and the electronegative oxygen atoms of the water molecules attract the electropositive imidazolium rings of [bmim][BF4]. Hence, the water molecules are like a glue that stick the IL and OE units more tightly together and thus make the microemulsion system more stable. Considering the unique solubilization behavior of added water molecules, the IL/O microemulsion system may be used as a medium to prepare porous or hollow nanomaterials by hydrolysis reactions. PMID:17177215

  17. Role of solubilized water in the reverse ionic liquid microemulsion of 1-butyl-3-methylimidazolium tetrafluoroborate/TX-100/benzene.

    PubMed

    Gao, Yan'an; Li, Na; Zheng, Liqiang; Bai, Xiangtao; Yu, Li; Zhao, Xueyan; Zhang, Jin; Zhao, Mingwei; Li, Zhen

    2007-03-15

    The ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate (bmimBF4) can form nonaqueous microemulsions with benzene by the aid of nonionic surfactant TX-100. The effect of water on ionic liquid-in-oil (IL/O) microemulsions was studied, and it was shown that the addition of small amount of water to the IL microemulsion contributed to the stability of microemulsion and thus increased the amount of solubilized bmimBF4 in the microemulsion. The conductivity measurements also showed that the attractive interactions between IL microdroplets were weakened, that is, the IL/O microemulsion becomes more stable in the present of some water. Fourier transform IR was carried out to analyze the states of the added water, and the result showed that these water molecules mainly behaved as bound water and trapped water, indicating that the water molecules are located in the palisade layers of the IL/O microemulsion. Furthermore, 1H NMR and 19F NMR spectra suggested that the added water molecules built the hydrogen binding network of imidazolium cations and H2O, BF4- anion and H2O, and at the same time the electronegative oxygen atoms of the oxyethylene units of TX-100 and water in the palisade layers, which made the palisade layers more firm and thus increased the stability of the microemulsion. The study can help in further understanding the formation mechanism of microemulsions. In addition, the characteristic solubilization behavior of the added water can provide an aqueous interface film for hydrolysis reactions and therefore may be used as an ideal medium to prepare porous or hollow nanomaterials. PMID:17305388

  18. Expression of p13MTCP1 is restricted to mature T-cell proliferations with t(X;14) translocations.

    PubMed

    Madani, A; Choukroun, V; Soulier, J; Cacheux, V; Claisse, J F; Valensi, F; Daliphard, S; Cazin, B; Levy, V; Leblond, V; Daniel, M T; Sigaux, F; Stern, M H

    1996-03-01

    T-cell prolymphocytic leukemia (T-PLL), a rare form of mature T-cell leukemias, and ataxia telangiectasia clonal proliferation, a related condition occurring in patients suffering from ataxia telangiectasia, have been associated to translocations involving the 14q32.1 or Xq28 regions, where are located the TCL1 and MTCP1 putative oncogenes, respectively. The MTCP1 gene is involved in the t(X;14)(q28;q11) translocation associated with these T-cell proliferations. Alternative splicing generates type A and B transcripts that potentially encode two entirely distinct proteins; type A transcripts code for a small mitochondrial protein, p8MTCP1, and type B transcripts, containing an additional open reading frame, may code for 107 amino-acid protein, p13MTCP1. The recently cloned TCL1 gene, also involved in translocations and inversions associated with T-cell proliferations, codes for a 14-kD protein that displays significant homology with p13MTCP1. We have generated rabbit antisera against this putative p13MTCP1 protein and screened for expression of p13MTCP1 normal lymphoid tissues and 33 cases of immature and mature lymphoid T-cell proliferations using a sensitive Western blot assay. We also investigated the MTCP1 locus configuration by Southern blot analysis. The p13MTCP1 protein was detected in the three T-cell proliferations with MTCP1 rearrangements because of t(X;14) translocations, but neither in normal resting and activated lymphocytes nor in the other T-cell leukemias. Our data support the hypothesis that p13MTCP1 and p14TCL1 form a new protein family that plays a key role in the pathogenesis of T-PLL and related conditions.

  19. Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.

    PubMed

    Henriques, Sónia Troeira; Deplazes, Evelyne; Lawrence, Nicole; Cheneval, Olivier; Chaousis, Stephanie; Inserra, Marco; Thongyoo, Panumart; King, Glenn F; Mark, Alan E; Vetter, Irina; Craik, David J; Schroeder, Christina I

    2016-08-12

    ProTx-II is a disulfide-rich peptide toxin from tarantula venom able to inhibit the human voltage-gated sodium channel 1.7 (hNaV1.7), a channel reported to be involved in nociception, and thus it might have potential as a pain therapeutic. ProTx-II acts by binding to the membrane-embedded voltage sensor domain of hNaV1.7, but the precise peptide channel-binding site and the importance of membrane binding on the inhibitory activity of ProTx-II remain unknown. In this study, we examined the structure and membrane-binding properties of ProTx-II and several analogues using NMR spectroscopy, surface plasmon resonance, fluorescence spectroscopy, and molecular dynamics simulations. Our results show a direct correlation between ProTx-II membrane binding affinity and its potency as an hNaV1.7 channel inhibitor. The data support a model whereby a hydrophobic patch on the ProTx-II surface anchors the molecule at the cell surface in a position that optimizes interaction of the peptide with the binding site on the voltage sensor domain. This is the first study to demonstrate that binding of ProTx-II to the lipid membrane is directly linked to its potency as an hNaV1.7 channel inhibitor. PMID:27311819

  20. Geothermal development plan: Maricopa county

    SciTech Connect

    White, D.H.

    1981-01-01

    Maricopa county is the area of Arizona receiving top priority since it contains over half of the state's population. The county is located entirely within the Basin and Range physiographic region in which geothermal resources are known to occur. Several approaches were taken to match potential users to geothermal resources. One approach involved matching some of the largest facilities in the county to nearby geothermal resources. Other approaches involved identifying industrial processes whose heat requirements are less than the average assessed geothermal reservoir temperature of 110/sup 0/C (230/sup 0/F). Since many of the industries are located on or near geothermal resources, geothermal energy potentially could be adapted to many industrial processes.

  1. Archuleta County CO Lineaments

    DOE Data Explorer

    Zehner, Richard E.

    2012-01-01

    Citation Information: Originator: Earth Science &Observation Center (ESOC), CIRES, University of Colorado at Boulder Originator: Geothermal Development Associates, Reno, Nevada Publication Date: 2012 Title: Archuleta Lineaments Edition: First Publication Information: Publication Place: Reno Nevada Publisher: Geothermal Development Associates, Reno, Nevada Description: This layer traces apparent topographic and air-photo lineaments in the area around Pagosa springs in Archuleta County, Colorado. It was made in order to identify possible fault and fracture systems that might be conduits for geothermal fluids. Geothermal fluids commonly utilize fault and fractures in competent rocks as conduits for fluid flow. Geothermal exploration involves finding areas of high near-surface temperature gradients, along with a suitable “plumbing system” that can provide the necessary permeability. Geothermal power plants can sometimes be built where temperature and flow rates are high. To do this, georeferenced topographic maps and aerial photographs were utilized in an existing GIS, using ESRI ArcMap 10.0 software. The USA_Topo_Maps and World_Imagery map layers were chosen from the GIS Server at server.arcgisonline.com, using a UTM Zone 13 NAD27 projection. This line shapefile was then constructed over that which appeared to be through-going structural lineaments in both the aerial photographs and topographic layers, taking care to avoid manmade features such as roads, fence lines, and right-of-ways. These lineaments may be displaced somewhat from their actual location, due to such factors as shadow effects with low sun angles in the aerial photographs. Note: This shape file was constructed as an aid to geothermal exploration in preparation for a site visit for field checking. We make no claims as to the existence of the lineaments, their location, orientation, and nature. Spatial Domain: Extent: Top: 4132831.990103 m Left: 311979.997741 m Right: 331678.289280 m Bottom: 4116067

  2. 76 FR 13172 - Placer County Water Agency

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-10

    ... Energy Regulatory Commission Placer County Water Agency Notice of Application Tendered for Filing with... Filed: February 23, 2011 d. Applicant: Placer County Water Agency e. Name of Project: Middle Fork... Manager, Placer County Water Agency, 144 Ferguson Road, Auburn, CA 95603; Telephone: (530) 823-4490....

  3. Community Analysis for the Pitkin County Library.

    ERIC Educational Resources Information Center

    Kirwin, Florence M.

    This document analyzes the social and demographic characteristics of Pitkin County, Colorado (population 12,000) and the Pitkin County Library located in Aspen (24,000 volumes). The report contains statistics gathered from the 1978 Mid-Term U.S. Bureau Census of Pitkin County, as well as other statistics from local, state, and federal sources; the…

  4. Community Types and Mortality in Georgia Counties

    ERIC Educational Resources Information Center

    Young, Frank W.

    2012-01-01

    Using an "ecological regional analysis" methodology for defining types of communities and their associated mortality rates, this study of Georgia's 159 counties finds that the suburban and town centered counties have low mortality while the city-centered type predicts low mortality for the whites. The military-centered counties do not predict. The…

  5. The surficial aquifer in Pinellas County, Florida

    USGS Publications Warehouse

    Causseaux, K.W.

    1985-01-01

    The surficial aquifer in Pinellas County, Florida, contains potable water throughout most of the county and is a potential source of water to augment the public supply that is presently imported from adjacent counties. The county accounts for 38 percent of the public supply consumption of ground water in the 11-county area of west-central Florida and 68 percent of this water is imported from two adjacent counties. The surficial aquifer has a saturated thickness of more than 30 feet throughout most of the county. Specific capacity per foot of screen for wells is less than 0.1 gallon per minute per foot of drawdown in some parts of the county, but yield is sufficient in most of the county for many small uses with shallow-well pumps. Minimum potential yield varies from 5 gallons per minute in the northern part of the county to more than 30 gallons per minute in the south. Concentrations of iron are high enough in parts of the county to cause staining. Chloride concentrations are less than 100 milligrams per liter in most of the county and do not pose a problem for many uses. (USGS)

  6. Trouble Brewing in Orange County. Policy Brief

    ERIC Educational Resources Information Center

    Buck, Stuart

    2010-01-01

    Orange County will soon face enormous budgetary pressures from the growing deficits in public pensions, both at a state and local level. In this policy brief, the author estimates that Orange County faces a total $41.2 billion liability for retiree benefits that are underfunded--including $9.4 billion for the county pension system and an estimated…

  7. Fresno County Mock Trial Competition.

    ERIC Educational Resources Information Center

    Fresno City Unified School District, CA.

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: The Fresno County Office of Education and the Fresno Unified School District hosted the Mock Trial Competition. The state competition is sponsored by the Constitutional Rights Foundation, with cosponsorship from the California State Bar Association and the California Young Lawyer's Association. This…

  8. Composting in Prince William County

    SciTech Connect

    Lyons, K.

    1995-10-01

    Hidden in a small industrial corner of Prince Williams County, in Northern Virginia, a composting facility, after its first flourishing year in business, has found itself part of a symbiotic triangle. Along with a landfill and a waste-to-energy (WTE) plant, the composting facility is one of three programs that make up a joint public-private venture and form a interjurisdictional solid waste/refuse exchange agreement. Faced with the prospects of having to close a landfill at the end of the year, a mandate on yard waste collection that was increasing collection tonnage, and no room for further landfill development, Fairfax County, with approximately 900,000 residents, needed help. In a turn-around situation, Prince William County--with approximately 240,000 residents, a low budget, and much space available for development--responded. Together the counties created a solid waste exchange. The basis for the program is a unity between the local governments on some solid waste issues and a composting facility. Composting, specifically yard waste composting, has been among the fastest-growing aspects of waste management. In 1990, the nation was composting 2% of its solid waste. By the end of 1995, according to the US EPA, between 4% and 7% of solid waste will be recovered through composting. The number of yard waste composting facilities operating has increased from 651 in 1988 to more than 3,000 in 1994.

  9. Somerset County Employer Needs Assessment.

    ERIC Educational Resources Information Center

    Rephann, Terance J.

    Allegany Community College in Cumberland, Maryland, conducted an employer assessment survey of Somerset County businesses during the winter of 1995 in order to provide evaluation data for planning and curriculum development for the secondary and postsecondary educational institutions. The survey was mailed to 760 establishments, with a 29 percent…

  10. Kinship Care in Walton County.

    ERIC Educational Resources Information Center

    Charon, Sara L.; Nackerud, Larry

    1996-01-01

    The quality of life of maltreated children placed with relatives was examined through interviews with nine families in Walton County (Georgia) who had taken in related children. Over half of the children had experienced some improvement in home life, school performance, and their physical and mental status. Kinship care families indicated needs…

  11. Southern Nevada Library Services; Serving Lincoln County, Nye County, Esmeralda County through the Clark County Library District: An Evaluation.

    ERIC Educational Resources Information Center

    Dalton, Phyllis I.

    An anecdotal review covers the first year of increased library service in Nye, Lincoln, and Esmeralda Counties, Nevada, under the Southern Nevada Library Services project funded by the Library Services and Construction Act. Using information from questionnaires and site visits, the extent of library services in each community in the area is…

  12. Truancy in Yolo County, California.

    ERIC Educational Resources Information Center

    Sommer, Barbara; Tyburczy, Jason

    The problem of truancy in the elementary and junior high schools of California's Yolo County was investigated during the 1980-81 academic year by means of questionnaires completed by 16 school principals and interviews with 30 people representing schools, school district offices, law enforcement agencies, the Department of Social Services, and the…

  13. Geothermal development plan: Pima County

    NASA Astrophysics Data System (ADS)

    White, D. H.; Goldstone, L. A.

    1982-08-01

    The Pima County Area Development evaluated the county-wide market potential for utilizing geothermal energy. Four potential geothermal resource areas with temperatures less than 1000 C (2120 F) were identified. In addition, one area is identified as having a temperature of 1470 F (2970 F). Geothermal resources are found to occur in Tecson where average population growth rates of two to three percent per year are expected over the next 40 years. Rapid growth in the manufacturing sector and the existence of major copper mines provide opportunities for the direct utilization of geothermal energy. However, available water supplies are identified as a major constraing to projected growth. A regional energy analysis, future predictions for energy consumption, and energy prices are given. Potential geothermal users in Pima County are identified and projections of maximum economic geothermal utilization are given. One hundred fifteen firms in 32 industrial classes have some potential for geothermal use are identified. In addition, 26 agribusiness firms were found in the county.

  14. Hydrogeology of Wood County, Wisconsin

    USGS Publications Warehouse

    Batten, W.G.

    1989-01-01

    The average rate of ground·water pumpage in Wood County in 1985 was 9.7 million gallons per day. Of this rate, about 6 million gallons per day is pumped from municipal-supply wells in seven communities.An additional 1.08 million gallons per day is pumped for agricultural irrigation.

  15. Measles in rural Ohio county.

    PubMed

    Orenstein, W A; Irvin, J; Jennings, M R; Giandelia, J; Halpin, T J; Marks, J S; Conrad, J L

    1980-06-01

    Between December 23, 1975, and March 31, 1976, 169 cases of measles were reported from Defiance County, Ohio, a small rural county in the northwest corner of the State. The outbreak spread from a single junior high school basketball player to eventually involve 19 of the 28 county schools. Among the affected schools, measles attack rates varied from 0.3-7.2% with a mean of 2.0%. A likely source of illness was determined for 160 of the 169 cases (95%). Intraschool transmission was most common, accounting for 97 of the 169 cases (57%) followed by sibling contact for 23 cases (14%). The pattern of measles spread was complex and would have been difficult to predict in advance even if surveillance systems reported each case the day it occurred. A control program held between February 2 and February 20, 1976, vaccinated 5145 of the 11,114 (46.3%) county schoolchildren. Forty-four cases of measles occurred 4 or more days following school clinics, 22 (50%) in children who requested measles vaccine at school clinics, 17 of whom were actually vaccinated. Most of the other cases occurred in students whose parents thought their children to be protected. Measles is a disease which spreads rapidly in a complex pattern over wide geographic areas. A control program vaccinating a large proportion of the children without definitive history of adequate vaccination or disease was apprently effective in curtailing the outbreak.

  16. Differential effects of the recombinant toxin PnTx4(5-5) from the spider Phoneutria nigriventer on mammalian and insect sodium channels.

    PubMed

    Paiva, Ana L B; Matavel, Alessandra; Peigneur, Steve; Cordeiro, Marta N; Tytgat, Jan; Diniz, Marcelo R V; de Lima, Maria Elena

    2016-02-01

    The toxin PnTx4(5-5) from the spider Phoneutria nigriventer is extremely toxic/lethal to insects but has no macroscopic behavioral effects observed in mice after intracerebral injection. Nevertheless, it was demonstrated that it inhibits the N-methyl-d-aspartate (NMDA) - subtype of glutamate receptors of cultured rat hippocampal neurons. PnTx4(5-5) has 63% identity to PnTx4(6-1), another insecticidal toxin from P. nigriventer, which can slow down the sodium current inactivation in insect central nervous system, but has no effect on Nav1.2 and Nav1.4 rat sodium channels. Here, we have cloned and heterologous expressed the toxin PnTx4(5-5) in Escherichia coli. The recombinant toxin rPnTx4(5-5) was tested on the sodium channel NavBg from the cockroach Blatella germanica and on mammalian sodium channels Nav1.2-1.6, all expressed in Xenopus leavis oocytes. We showed that the toxin has different affinity and mode of action on insect and mammalian sodium channels. The most remarkable effect was on NavBg, where rPnTx4(5-5) strongly slowed down channel inactivation (EC50 = 212.5 nM), and at 1 μM caused an increase on current peak amplitude of 105.2 ± 3.1%. Interestingly, the toxin also inhibited sodium current on all the mammalian channels tested, with the higher current inhibition on Nav1.3 (38.43 ± 8.04%, IC50 = 1.5 μM). Analysis of activation curves on Nav1.3 and Nav1.5 showed that the toxin shifts channel activation to more depolarized potentials, which can explain the sodium current inhibition. Furthermore, the toxin also slightly slowed down sodium inactivation on Nav1.3 and Nav1.6 channels. As far as we know, this is the first araneomorph toxin described which can shift the sodium channel activation to more depolarized potentials and also slows down channel inactivation.

  17. Hydrogeology of Webb County, Texas

    USGS Publications Warehouse

    Lambert, Rebecca B.

    2004-01-01

    Introduction: Webb County, in semiarid South Texas on the U.S.-Mexico border, is a region confronted by increasing stresses on natural resources. Laredo (fig. 1), the largest city in Webb County (population 193,000 in 2000), was one of the 10 fastest-growing metropolitan areas in the country during 1990-2000 (Perry and Mackun, 2001). Commercial and industrial activities have expanded throughout the region to support the maquiladora industry (manufacturing plants in Mexico) along the border and other growth as a result of the passage of the North American Free Trade Agreement. The Rio Grande currently (2002) is the primary source of public water supply for Laredo and other cities along the border in Webb County (fig. 1). Other cities, such as Bruni and Mirando City in the southeastern part of the county, rely on ground-water supplies to meet municipal demands. Increased water demand associated with development and population growth in the region has increased the need for the City of Laredo and Webb County to evaluate alternative water sources to meet future demand. Possible options include (1) supplementing the surface-water supply with ground water, and (2) applying artificial storage and recovery (ASR) technology to recharge local aquifers. These options raise issues regarding the hydraulic capability of the aquifers to store economically substantial quantities of water, current or potential uses of the resource, and possible effects on the quality of water resulting from mixing ground water with alternative source waters. To address some of these issues, the U.S. Geological Survey (USGS), in cooperation with the City of Laredo, began a study in 1996 to assess the ground-water resources of Webb County. A hydrogeologic study was conducted to review and analyze available information on the hydrogeologic units (aquifers and confining units) in Webb County, to locate available wells in the region with water-level and water-quality information from the aquifers, and

  18. Chester County ground-water atlas, Chester County, Pennsylvania

    USGS Publications Warehouse

    Ludlow, Russell A.; Loper, Connie A.

    2004-01-01

    Chester County encompasses 760 square miles in southeastern Pennsylvania. Groundwater- quality studies have been conducted in the county over several decades to address specific hydrologic issues. This report compiles and describes water-quality data collected during studies conducted mostly after 1990 and summarizes the data in a county-wide perspective. In this report, water-quality constituents are described in regard to what they are, why the constituents are important, and where constituent concentrations vary relative to geology or land use. Water-quality constituents are grouped into logical units to aid presentation: water-quality constituents measured in the field (pH, alkalinity, specific conductance, and dissolved oxygen), common ions, metals, radionuclides, bacteria, nutrients, pesticides, and volatile organic compounds.Waterquality constituents measured in the field, common ions (except chloride), metals, and radionuclides are discussed relative to geology. Bacteria, nutrients, pesticides, and volatile organic compounds are discussed relative to land use. If the U.S. Environmental Protection Agency (USEPA) or Chester County Health Department has drinkingwater standards for a constituent, the standards are included. Tables and maps are included to assist Chester County residents in understanding the water-quality constituents and their distribution in the county. Ground water in Chester County generally is of good quality and is mostly acidic except in the carbonate rocks and serpentinite, where it is neutral to strongly basic. Calcium carbonate and magnesium carbonate are major constituents of these rocks. Both compounds have high solubility, and, as such, both are major contributors to elevated pH, alkalinity, specific conductance, and the common ions. Elevated pH and alkalinity in carbonate rocks and serpentinite can indicate a potential for scaling in water heaters and household plumbing. Low pH and low alkalinity in the schist, quartzite, and

  19. Linear DNA for rapid prototyping of synthetic biological circuits in an Escherichia coli based TX-TL cell-free system.

    PubMed

    Sun, Zachary Z; Yeung, Enoch; Hayes, Clarmyra A; Noireaux, Vincent; Murray, Richard M

    2014-06-20

    Accelerating the pace of synthetic biology experiments requires new approaches for rapid prototyping of circuits from individual DNA regulatory elements. However, current testing standards require days to weeks due to cloning and in vivo transformation. In this work, we first characterized methods to protect linear DNA strands from exonuclease degradation in an Escherichia coli based transcription-translation cell-free system (TX-TL), as well as mechanisms of degradation. This enabled the use of linear DNA PCR products in TX-TL. We then compared expression levels and binding dynamics of different promoters on linear DNA and plasmid DNA. We also demonstrated assembly technology to rapidly build circuits entirely in vitro from separate parts. Using this strategy, we prototyped a four component genetic switch in under 8 h entirely in vitro. Rapid in vitro assembly has future applications for prototyping multiple component circuits if combined with predictive computational models.

  20. Headspace vapor characterization of Hanford Waste Tank 241-TX-111: Results from samples collected on October 12, 1995. Tank Vapor Characterization Project

    SciTech Connect

    Pool, K.H.; Clauss, T.W.; Evans, J.C.

    1996-06-01

    This report describes the results of vapor samples taken from the headspace of waste storage tank 241-TX-111 (Tank TX-111) at the Hanford Site in Washington State. Pacific Northwest National Laboratory (PNNL) contracted with Westinghouse Hanford Company (WHC) to provide sampling devices and analyze samples for inorganic and organic analytes collected from the tank headspace and ambient air near the tank. The analytical work was performed by the PNNL Vapor Analytical Laboratory (VAL) by the Tank Vapor Characterization Project. Work performed was based on a sample and analysis plan (SAP) prepared by WHC. The SAP provided job-specific instructions for samples, analyses, and reporting. The SAP for this sample job was {open_quotes}Vapor Sampling and Analysis Plan{close_quotes}, and the sample job was designated S5069. Samples were collected by WHC on October 12, 1995, using the Vapor Sampling System (VSS), a truck-based sampling method using a heated probe inserted into the tank headspace.

  1. Vapor space characterization of waste tank 241-TX-105: Results from samples collected on December 20, 1994. Waste Tank Vapor Project

    SciTech Connect

    Klinger, G.S.; Ligotke, M.W.; Lucke, R.B.

    1995-06-01

    This document presents the details of the inorganic and organic analysis that was performed on samples from the headspace of Hanford waste tank 241-TX-105. The results described were obtained to support the safety and toxicological evaluations. A summary of the results for the inorganic and organic analytes is included, as well as, a detailed description of the results which appears in the text.

  2. Borehole Data Package for Calendar Year 2000-2001 RCRA Wells at Single-Shell Tank Waste Management Area TX-TY

    SciTech Connect

    Horton, Duane G.; Hodges, Floyd N.

    2001-08-15

    This document compiles information on the drilling and construction, well development, pump installation, and sediment and groundwater sampling applicable to the installation of five new RCRA wells in calendar year 2000 - 2001 at WMA TX-TY. Appendix A contains the Well Summary Sheets (as-built diagrams), the Well Construction Summary Reports, and the geologist's logs; Appendix B contains physical properties data; and Appendix C contains the borehole geophysical logs.

  3. t(X;14)(p11.4;q32.33) is recurrent in marginal zone lymphoma and up-regulates GPR34

    PubMed Central

    Baens, Mathijs; Finalet Ferreiro, Julio; Tousseyn, Thomas; Urbankova, Helena; Michaux, Lucienne; de Leval, Laurence; Dierickx, Daan; Wolter, Pascal; Sagaert, Xavier; Vandenberghe, Peter; De Wolf-Peeters, Christiane; Wlodarska, Iwona

    2012-01-01

    Genetic events underlying pathogenesis of nodal and extranodal marginal zone lymphoma are not completely understood. We report here a novel t(X;14)(p11.4;q32.33) identified in 4 lymphoma cases: 2 with a mucosa-associated lymphoid tissue lymphoma, one with a nodal marginal zone lymphoma and one with gastric diffuse large B-cell lymphoma. In all cases, lymphoma evolved from a previous auto-immune disorder. Fluorescence in situ hybridization and molecular studies showed that t(X;14), which is mediated by immunoglobulin heavy chain locus, targets the GPR34 gene at Xp11.4. Upregulation of GPR34 mRNA and aberrant expression of GPR34 protein has been demonstrated in 3 presented cases by quantitative real-time polymerase chain reaction and immunohistochemistry, respectively. GPR34 belongs to the largest family of cell surface molecules involved in signal transmission that play important roles in many physiological and pathological processes, including tumorigenesis. Although functional consequences of t(X;14) have not been identified, our studies suggest that up-regulated GPR34 activate neither nuclear factor-κB nor ELK-related tyrosine kinase. PMID:22058210

  4. t(X;14)(p11.4;q32.33) is recurrent in marginal zone lymphoma and up-regulates GPR34.

    PubMed

    Baens, Mathijs; Finalet Ferreiro, Julio; Tousseyn, Thomas; Urbankova, Helena; Michaux, Lucienne; de Leval, Laurence; Dierickx, Daan; Wolter, Pascal; Sagaert, Xavier; Vandenberghe, Peter; De Wolf-Peeters, Christiane; Wlodarska, Iwona

    2012-02-01

    Genetic events underlying pathogenesis of nodal and extranodal marginal zone lymphoma are not completely understood. We report here a novel t(X;14)(p11.4;q32.33) identified in 4 lymphoma cases: 2 with a mucosa-associated lymphoid tissue lymphoma, one with a nodal marginal zone lymphoma and one with gastric diffuse large B-cell lymphoma. In all cases, lymphoma evolved from a previous auto-immune disorder. Fluorescence in situ hybridization and molecular studies showed that t(X;14), which is mediated by immunoglobulin heavy chain locus, targets the GPR34 gene at Xp11.4. Upregulation of GPR34 mRNA and aberrant expression of GPR34 protein has been demonstrated in 3 presented cases by quantitative real-time polymerase chain reaction and immunohistochemistry, respectively. GPR34 belongs to the largest family of cell surface molecules involved in signal transmission that play important roles in many physiological and pathological processes, including tumorigenesis. Although functional consequences of t(X;14) have not been identified, our studies suggest that up-regulated GPR34 activate neither nuclear factor-κB nor ELK-related tyrosine kinase. PMID:22058210

  5. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.

    PubMed

    Murray, Justin K; Ligutti, Joseph; Liu, Dong; Zou, Anruo; Poppe, Leszek; Li, Hongyan; Andrews, Kristin L; Moyer, Bryan D; McDonough, Stefan I; Favreau, Philippe; Stöcklin, Reto; Miranda, Les P

    2015-03-12

    NaV1.7 is a voltage-gated sodium ion channel implicated by human genetic evidence as a therapeutic target for the treatment of pain. Screening fractionated venom from the tarantula Grammostola porteri led to the identification of a 34-residue peptide, termed GpTx-1, with potent activity on NaV1.7 (IC50 = 10 nM) and promising selectivity against key NaV subtypes (20× and 1000× over NaV1.4 and NaV1.5, respectively). NMR structural analysis of the chemically synthesized three disulfide peptide was consistent with an inhibitory cystine knot motif. Alanine scanning of GpTx-1 revealed that residues Trp(29), Lys(31), and Phe(34) near the C-terminus are critical for potent NaV1.7 antagonist activity. Substitution of Ala for Phe at position 5 conferred 300-fold selectivity against NaV1.4. A structure-guided campaign afforded additive improvements in potency and NaV subtype selectivity, culminating in the design of [Ala5,Phe6,Leu26,Arg28]GpTx-1 with a NaV1.7 IC50 value of 1.6 nM and >1000× selectivity against NaV1.4 and NaV1.5.

  6. Intermediate valence to heavy fermion through a quantum phase transition in Yb3(Rh 1 -xTx )4Ge13 (T =Co ,Ir ) single crystals

    NASA Astrophysics Data System (ADS)

    Rai, Binod K.; Oswald, Iain W. H.; Chan, Julia Y.; Morosan, E.

    2016-01-01

    Single crystals of Yb3(Rh 1 -xTx )4Ge13 (T =Co ,Ir ) have been grown using the self-flux method. Powder x-ray diffraction data on these compounds are consistent with the cubic structure with space group P m 3 ¯n . Intermediate-valence behavior is observed in Yb3(Rh 1 -xTx )4Ge13 upon T = Co doping, while T = Ir doping drives the system into a heavy-fermion state. Antiferromagnetic order is observed in the Ir-doped samples Yb3(Rh 1 -xTx )4Ge13 for 0.5

  7. Intermediate valence to heavy fermion through a quantum phase transition in Yb3(Rh1-xTx)4Ge13 (T = Co, Ir) single crystals

    NASA Astrophysics Data System (ADS)

    Rai, Binod; Morosan, Emilia

    Single crystals of Yb3(Rh1-x Tx)4Ge13 (T = Co, Ir) have been grown using the self-flux method. Powder X-ray diffraction data on these compounds are consistent with the cubic structure with space group Pm 3 n . Intermediate valence behavior is observed in Yb3(Rh1-x Tx)4Ge13 upon T = Co doping, while T = Ir doping drives the system into a heavy fermion state. Antiferromagnetic order is observed in the Ir-doped samples Yb3(Rh1-x Tx)4Ge13 for 0.5 < x <= 1 with TN = 0.96 K for Yb3Ir4Ge13. With decreasing x, the magnetic order is suppressed towards a quantum critical point around xc = 0.5, accompanied by non-Fermi liquid behavior evidenced by logarithmic divergence of the specific heat and linear temperature dependence of the resistivity. The Fermi liquid behavior is recovered with the application of large magnetic fields. Gordon and Betty Moore Foundation EPiQS initiative through Grant GBMF4417 and Welch Foundation.

  8. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.

    PubMed

    Murray, Justin K; Ligutti, Joseph; Liu, Dong; Zou, Anruo; Poppe, Leszek; Li, Hongyan; Andrews, Kristin L; Moyer, Bryan D; McDonough, Stefan I; Favreau, Philippe; Stöcklin, Reto; Miranda, Les P

    2015-03-12

    NaV1.7 is a voltage-gated sodium ion channel implicated by human genetic evidence as a therapeutic target for the treatment of pain. Screening fractionated venom from the tarantula Grammostola porteri led to the identification of a 34-residue peptide, termed GpTx-1, with potent activity on NaV1.7 (IC50 = 10 nM) and promising selectivity against key NaV subtypes (20× and 1000× over NaV1.4 and NaV1.5, respectively). NMR structural analysis of the chemically synthesized three disulfide peptide was consistent with an inhibitory cystine knot motif. Alanine scanning of GpTx-1 revealed that residues Trp(29), Lys(31), and Phe(34) near the C-terminus are critical for potent NaV1.7 antagonist activity. Substitution of Ala for Phe at position 5 conferred 300-fold selectivity against NaV1.4. A structure-guided campaign afforded additive improvements in potency and NaV subtype selectivity, culminating in the design of [Ala5,Phe6,Leu26,Arg28]GpTx-1 with a NaV1.7 IC50 value of 1.6 nM and >1000× selectivity against NaV1.4 and NaV1.5. PMID:25658507

  9. Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels

    PubMed Central

    Escoubas, Pierre; Bernard, Cédric; Lambeau, Gérard; Lazdunski, Michel; Darbon, Hervé

    2003-01-01

    Acid-sensing ion channels (ASICs) are thought to be important ion channels, particularly for the perception of pain. Some of them may also contribute to synaptic plasticity, learning, and memory. Psalmotoxin 1 (PcTx1), the first potent and specific blocker of the ASIC1a proton-sensing channel, has been successfully expressed in the Drosophila melanogaster S2 cell recombinant expression system used here for the first time to produce a spider toxin. The recombinant toxin was identical in all respects to the native peptide, and its three-dimensional structure in solution was determined by means of 1H 2D NMR spectroscopy. Surface characteristics of PcTx1 provide insights on key structural elements involved in the binding of PcTx1 to ASIC1a channels. They appear to be localized in the β-sheet and the β-turn linking the strands, as indicated by electrostatic anisotropy calculations, surface charge distribution, and the presence of residues known to be implicated in channel recognition by other inhibitor cystine knot (ICK) toxins. PMID:12824480

  10. Microemulsions with surfactant TX100, cyclohexane, and an ionic liquid investigated by conductance, DLS, FTIR measurements, and study of solvent and rotational relaxation within this microemulsion.

    PubMed

    Pramanik, Rajib; Sarkar, Souravi; Ghatak, Chiranjib; Rao, Vishal Govind; Setua, Palash; Sarkar, Nilmoni

    2010-06-10

    Room-temperature ionic liquids (RTILs), N,N,N-trimethyl-N-propyl ammonium bis(trifluoromethanesulfonyl) imide ([N(3111)][Tf(2)N]), were substituted for polar water and formed nonaqueous microemulsions with cyclohexane by the aid of nonionic surfactant TX-100. The phase behavior of the ternary system was investigated, and microregions of [N(3111)][Tf(2)N]-in-cyclohexane (IL/O), bicontinuous, and cyclohexane-in-[N(3111)][Tf(2)N] (O/IL) were identified by traditional electrical conductivity measurements. Dynamic light scattering (DLS) revealed the formation of the IL microemulsions. The FTIR study of O-H stretching band of TX100 also supports this finding. The dynamics of solvent and rotational relaxation have been investigated in [N(3111)][Tf(2)N]/TX100/cyclohexane microemulsions using steady-state and time-resolved fluorescence spectroscopy as a tool and coumarin 480 (C-480) as a fluorescence probe. The size of the microemulsions increases with gradual addition of [N(3111)][Tf(2)N], which revealed from DLS measurement. This leads to the faster collective motions of cation and anions of [N(3111)][Tf(2)N], which contributes to faster solvent relaxation in microemulsions. PMID:20469906

  11. Impacts of Near-term Climate Change on Surface Water - Groundwater Availability in the Nueces River basin, TX

    NASA Astrophysics Data System (ADS)

    Sinha, T.; Kumar, M.

    2014-12-01

    In arid and semi-arid regions, sustainability of surface water and groundwater resources is highly uncertain in the face of climate change as well as under competing demands due to urbanization, population growth and water needs to support ecosystem services. Most studies on climate change impact assessment focus on either surface water or groundwater resources alone. In this study, we utilize a fully coupled surface water and groundwater model, Penn-State Integrated Hydrologic Model (PIHM), and recent climate change projections from Climate Models Inter-comparison Project-5 (CMIP5) to evaluate impacts of near-term climate change on water availability in the Nueces River basin, TX. After performing calibration and validation of PIHM over multiple sites, hindcast simulations will be performed over the 1981-2010 period using data from multiple General Circulation Models (GCMs) obtained from the CMIP5 Project. The results will be compared to the observed data to understand added utility of hindcasts in improving the estimation of surface water and groundwater resources. Finally, we will assess the impacts of climate change on both surface water and groundwater resources over the next 20-30 years, which is a relevant time period for water management decisions.

  12. Spread of vaccinia virus through shaving during military training, Joint Base San Antonio-Lackland, TX, June 2014.

    PubMed

    Webber, Bryant J; Montgomery, Jay R; Markelz, Ana E; Allen, Kahtonna C; Hunninghake, John C; Ritchie, Simon A; Pawlak, Mary T; Johnston, Lindsay A; Oliver, Tiffany A; Winterton, Brad S

    2014-08-01

    Although naturally occurring smallpox virus was officially declared eradicated in 1980, concern for biological warfare prompted the U.S. Government in 2002 to recommend smallpox vaccination for select individuals. Vaccinia, the smallpox vaccine virus, is administered into the skin, typically on the upper arm, where the virus remains viable and infectious until the scab falls off and the epidermis is fully intact - typically 2-4 weeks. Adverse events following smallpox vaccination may occur in the vaccinee, in individuals who have contact with the vaccinee (i.e., secondary transmission), or in individuals who have contact with the vaccinee's contact (i.e., tertiary transmission). In June 2014 at Joint Base San Antonio-Lackland, TX, two cases of inadvertent inoculation of vaccinia and one case of a non-viral reaction following vaccination occurred in the security forces training squadron. This includes the first reported case of shaving as the likely source of autoinoculation after contact transmission. This paper describes the diagnosis and treatment of these cases, the outbreak investigation, and steps taken to prevent future transmission.

  13. An investigation of several aspects of LANDSAT-5 data quality. [Palmer County, Shelby, mt; White sands, NM; Great Salt Lake, UT; San Matted Bridge and Sacramento, California

    NASA Technical Reports Server (NTRS)

    Wrigley, R. C. (Principal Investigator)

    1984-01-01

    Band-to-band registration, geodetic registration, interdector noise, and the modulation transfer function (MTE) are discussed for the Palmer County; TX scene. Band combinations for several LANDSAT 4 and LANDSAT 5 scenes; the geodetic registration test for the Sacramento, CA area; periodic noise components in TM band 5; and grey level measurements by detector for Great Salt Lake (UT) dark water forescans and backscans are considered. Results of MTF analyses of the San Mateo Bridge and of TM high resolution and aerial Daedalus scanner imagery are consistent and appear to be repeatable. An oil-on-sand target was constructed on the White Sands Missile Range in New Mexico. The two-image analysis procedure used is summarized.

  14. 7 CFR 7.11 - County committee members.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the county executive director, other employee of the county committee, or the county agricultural extension agent for the county. If the county agricultural extension agent is not selected as secretary to... Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF AGRICULTURAL STABILIZATION...

  15. 7 CFR 7.11 - County committee members.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the county executive director, other employee of the county committee, or the county agricultural extension agent for the county. If the county agricultural extension agent is not selected as secretary to... Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF AGRICULTURAL STABILIZATION...

  16. 7 CFR 7.11 - County committee members.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the county executive director, other employee of the county committee, or the county agricultural extension agent for the county. If the county agricultural extension agent is not selected as secretary to... Agriculture Office of the Secretary of Agriculture SELECTION AND FUNCTIONS OF AGRICULTURAL STABILIZATION...

  17. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 1 2012-01-01 2012-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  18. 7 CFR 7.25 - County executive director duties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 1 2011-01-01 2011-01-01 false County executive director duties. 7.25 Section 7.25... CONSERVATION STATE, COUNTY AND COMMUNITY COMMITTEES § 7.25 County executive director duties. (a) The county executive director shall execute the policies established by the county committee and be responsible for...

  19. 40 CFR 52.2285 - Control of evaporative losses from the filling of gasoline storage vessels in the Houston and San...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2285 Control of evaporative losses from the filling... containers and delivery vessels. (b) This section is applicable to the following counties in Texas: Harris... Bexar, Brazoria, Galveston, and Harris Counties which is subject to Texas Air Control Board Regulation...

  20. 40 CFR 52.2285 - Control of evaporative losses from the filling of gasoline storage vessels in the Houston and San...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2285 Control of evaporative losses from the filling... containers and delivery vessels. (b) This section is applicable to the following counties in Texas: Harris... Bexar, Brazoria, Galveston, and Harris Counties which is subject to Texas Air Control Board Regulation...

  1. 78 FR 10249 - Environmental Impact Statement: Will and Kankakee Counties, IL and Lake County, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... TRANSPORTATION Federal Highway Administration Environmental Impact Statement: Will and Kankakee Counties, IL and Lake County, IN AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Intent. SUMMARY... Federal Domestic Assistance Program Number 20.205, Highway Research, Planning and Construction....

  2. Water resources of Lehigh County, Pennsylvania

    USGS Publications Warehouse

    Wood, Charles R.; Flippo, Herbert N.; Lescinsky, Joseph B.; Barker, James L.

    1972-01-01

    Lehigh County occupies an area of 347 square miles in southeastern Pennsylvania. The northern part of Lehigh County is underlain by the Martinsburg Formation, which consists chiefly of shale and slate. The central part of the county, where most of the population centers are located and much of the urbanization is occurring, is underlain by alternating beds of limestone and dolomite. From oldest to youngest, these carbonate rocks are the Leithsville Formation, the Allentown Formation, the Beekmantown Group, and the Jacksonburg Formation. The southern part of the county is underlain chiefly by the shales, sandstones, and conglomerates of the Brunswick Formation and by metamorphic and igneous rocks.

  3. Waste source reduction county government case study

    SciTech Connect

    1990-12-31

    Itasca County is located in north-central Minnesota, has a population of 42,000 and is known for its forests and scenic waterways. With Beltrami County, it contains the upper watershed of the Mississippi River. Its major industries are timber and tourism. Itasca County government made a commitment to source reduce its waste as much as possible. Secondarily, what they could not reduce they committed themselves to recycle. The project demonstrates functional reduction in practice. It shows that reduction is a realistic goal for county governments and that reduction can be measured on a waste stream by waste stream basis.

  4. Digital computer processing of LANDSAT data for North Alabama. [Linestone County, Madison County, Jackson County, Marshall County, and DeKalb County

    NASA Technical Reports Server (NTRS)

    Bond, A. D.; Atkinson, R. J.; Lybanon, M.; Ramapriyan, H. K.

    1977-01-01

    Computer processing procedures and programs applied to Multispectral Scanner data from LANDSAT are described. The output product produced is a level 1 land use map in conformance with a Universal Transverse Mercator projection. The region studied was a five-county area in north Alabama.

  5. 75 FR 26709 - Clarke County Water Supply Project, Clarke County, IA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... Natural Resources Conservation Service Clarke County Water Supply Project, Clarke County, IA AGENCY... Water Supply Project, Clarke County, Iowa. ] FOR FURTHER INFORMATION CONTACT: Richard Sims, State... comments by NRCS information related to water supply demand requirements for permitting by the State...

  6. 78 FR 29202 - Environmental Impact Statement: Grand Forks County, North Dakota and Polk County, Minnesota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... Federal Highway Administration Environmental Impact Statement: Grand Forks County, North Dakota and Polk... prepared for a proposed highway project in Grand Forks County, North Dakota and Polk County, Minnesota. FOR... Sorlie Bridge over the Red River between Grand Forks, North Dakota and East Grand Forks,...

  7. 75 FR 42815 - Fulton County, LLC-Abandonment Exemption-in Fulton County, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ... Surface Transportation Board Fulton County, LLC--Abandonment Exemption--in Fulton County, IN Fulton County, LLC (FC), filed a verified notice of exemption under 49 CFR 1152 subpart F--Exempt Abandonments to... exemption, any employee adversely affected by the abandonment shall be protected under Oregon Short...

  8. The Economic Impact of Schenectady County Community College on Schenectady County, 1981-82.

    ERIC Educational Resources Information Center

    Chestnut, Erma Ruth

    This report on the economic impact of Schenectady County Community College (SCCC) uses a modification of the Caffrey and Isaacs model to assess SCCC-related local business volume, SCCC costs and benefits to the Schenectady County government, and the likely impact on the county if SCCC did not exist. Part I provides background to the study,…

  9. 75 FR 25308 - Environmental Impact Statement: Winnebago County, IL and Rock County, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Highway Administration Environmental Impact Statement: Winnebago County, IL and Rock County, WI... Beloit, Rock County, Wisconsin to the interchange of Rockton Road and I-90 southeast of South...

  10. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  11. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  12. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  13. 33 CFR 100.905 - Door County Triathlon; Door County, WI.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Door County Triathlon; Door County, WI. 100.905 Section 100.905 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.905 Door County...

  14. 75 FR 54419 - Environmental Impact Statement: Yellowstone County, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ... Federal Highway Administration Environmental Impact Statement: Yellowstone County, MT AGENCY: Federal... highway project in Yellowstone County, Montana. FOR FURTHER INFORMATION CONTACT: Brian Hasselbach, Right... (I-90) and Old Highway 312 in or near the city of Billings, Yellowstone County, Montana....

  15. EXTERIOR VIEW LOOKING WEST ALONG JEFFERSON COUNTY 71 WITH RAILROAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EXTERIOR VIEW LOOKING WEST ALONG JEFFERSON COUNTY 71 WITH RAILROAD BRIDGE (RIGHT), SADDLEBAG COTTAGE (LEFT) AND COAL TRUCK. - Linn Crossing Trestle Bridge, Spanning County Road 71, Linn Crossing, Jefferson County, AL

  16. 111. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND, JUNE 1933. - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  17. 113. "EXISTING MAJOR HIGHWAYS". FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    113. "EXISTING MAJOR HIGHWAYS". FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND. JUNE 1933 - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  18. 112. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    112. 'PROPOSED CIRCULATION SYSTEM.' FROM FAIRFIELD COUNTY PLANNING ASSOCIATION, FAIRFIELD: THE FIRST PLANNED COUNTY IN NEW ENGLAND. JUNE 1933. - Merritt Parkway, Beginning in Greenwich & running 38 miles to Stratford, Greenwich, Fairfield County, CT

  19. Impact of Sea Level Rise on the Attenuation of Hurricane Storm Surge by Wetlands in Corpus Christi, TX

    NASA Astrophysics Data System (ADS)

    Ferreira, C.; Irish, J. L.; Olivera, F.

    2011-12-01

    Celso Ferreira1, Jennifer L. Irish2, Francisco Olivera3 1 Graduate Research Assistant, Department of Civil Engineering, Texas A&M University, College Station, TX 77843, email: celsoferreira@tamu.edu. 2 Associate Professor, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA 24061, email: jirish@vt.edu 3 Associate Professor, Department of Civil Engineering, Texas A&M University, College Station, TX 77843, email: folivera@civil.tamu.edu. Texas has historically faced severe hurricanes with Ike being the most recent major storm example. It is believed that coastal wetlands might reduce the impact of the storm surge on coastal areas, acting as a natural protection against hurricane flooding, especially for small hurricanes and tropical storms. Considering the expected rise in the mean sea level, wetland composition and spatial distribution are also expected to change as the environmental conditions change along the coast. We analyzed a range of Intergovernmental Panel on Climate Change (IPCC) projections for sea level rise (SLR) to simulate wetland alterations and evaluate their impact on hurricane storm surge. The analyses was conducted for Corpus Christi Bay using a pre-validated, physically based, hydrodynamic model (ADCIRC) and a wind and pressure field model (PBL) representing the physical properties of historical hurricane Bret. The calculations were performed using an unstructured numerical grid with 3.3 million nodes covering part of the Atlantic Ocean and the entire Gulf of Mexico (resolution from 2000 km to 50 meters at the coast). Wetlands are represented in the numerical model through their influence on the frictional resistance proprieties and bathymetric changes. To characterize the wetland types and their spatial distribution along the coast, we used six different land use databases from the National Land Cover Dataset (NLCD) (1992, 2001), the National Wetlands Inventory (NWI) (1993) and the Coastal Change Analysis Program (C

  20. Focalyx Dx, Bx, Tx et Apps: A novel contemporary fusion paradigm for the management of prostate cancer.

    PubMed

    Bianco, F J; Martínez-Salamanca, J I

    2016-07-01

    FocalyxTM conceived as a response to emerging evidence data across numerous cancer lesions that questions current standard treatment approaches that too often lead to detrimental quality of life yet delivering limited survival benefit, especially in-lieu of advances in imaging technology applicable to cancer patients. The Focalyx paradigm aims to control cancer with improvement in quality of life. We initially devised 5 milestones: 1- Consistently optimize Prostate MRI imaging using the novel published protocols adopted as guidelines by societies such as the European Society of Urology and Radiology; 2- Evaluate fusion platform software solutions that existed; 3- Determine best fusión platform for Focalyx on practicality, precision, and workflow premises; 4- Evaluate commercially available FDA approved ablative technologies to implement our treatment vision; 5- Design a treatment option that can be performed in the office setting under local anesthesia, which would not impact negatively QOL outcomes of Prostate Cancer patients and seamless constant nonintrusive practical patient-physician interaction by the Focalyx app that facilitates follow up and provides early warning signals shall any change in the disease dynamics emerge. Prostate cancer was identified as the pilot disease for Focalyx to deliver a "GPS" like solution for the prostate gland that destroys identifiable disease without adverse effects such as: cancer anxiety, urinary incontinence, loss of erections and ejaculation. Since September of 2013, over 300 men have been accrued in NCT02381990- clintrials.gov evaluating the feasibility of our solutions for imaging (FocalyxDx), Biopsy (FocalyxBx) and Treatment (FocalyxTx). In this review we detail the tools available to achieve the Focalyx paradigm for men with Prostate Cancer. PMID:27416639

  1. Integrating Infrastructure-Relevant Climate Projections into City Planning: Learning from Boulder CO, Austin TX and Washington DC

    NASA Astrophysics Data System (ADS)

    Stoner, A. M. K.; Hayhoe, K.

    2015-12-01

    Over the coming century, climate change has the potential to impact infrastructure in many different ways, particularly in population-dense areas that depend on transportation and built environments. Many of these impacts may occur via changes in the frequency and magnitude of extremes: high and low temperature, heat waves, precipitation, coastal flooding, and storm events. Having a better idea of how the climate might change locally, both within the near future as well as toward the end of the century, can give city planners and engineers guidance when designing new structures and when repairing and fortifying existing components of buildings, bridges, highways, sewers, ports, etc. However, the type of event and the amount of damages that may be incurred are often highly specific to a given location. Over the last 10 years, we have worked with a broad range of cities, states, non-profit organizations, and federal agencies to integrate climate projections into ongoing resiliency, sustainability, and management processes. Drawing on that experience, we describe the broad steps in assimilating climate information into existing decision-making frameworks relevant to most applications, as well as highlighting many of the unique aspects of these analyses using examples from our most recent work with three very different cities - Austin TX, Boulder CO and Washington DC. From initial conversations with local experts to identify relevant thresholds to final integration of projected changes into the planning processes of these cities, these case studies highlight the utility of including future climate projections into infrastructure planning, the challenges to doing so, and the over-arching importance of communication and interaction between infrastructure experts, engineers, and scientists.

  2. Impacts of cool cities on air quality: A preliminary modeling assessment for Nashville TN, Dallas TX and Atlanta GA

    SciTech Connect

    Taha, Haider

    1998-06-15

    Previous atmospheric modeling efforts that concentrated on the Los Angeles Basin suggested beneficial and significant air quality impacts from cool cities strategies. This paper discusses an extension of similar modeling efforts to three regions, Atlanta GA, Dallas - Ft. Worth TX, and Nashville TN, that experience smog and air quality problems. According to the older ozone air quality standard (120 ppb), these regions were classified as serious, moderate, and marginal, respectively, but may be out of compliance with respect to the newer, 80-ppb/8-hours standard. Results from this exploratory modeling work suggest a range of possible impacts on meteorological and air quality conditions. For example, peak ozone concentrations during each region's respective episode could be decreased by 1-6 ppb (conservative and optimistic scenarios, respectively) in Nashville, 5-15 ppb in Dallas - Fort Worth, and 5-12 ppb in Atlanta following implementation of cool cities. The reductions are generally smaller than those obtained from simulating the Los Angeles Basin but are still significant. In all regions, the simulations suggest, the net, domain-wide effects of cool cities are reductions in ozone mass and improvements in air quality. In Atlanta, Nashville, and Dallas, urban areas benefiting from reduced smog reach up to 8460, 7350, and 12870 km{sup 2} in area, respectively. Results presented in this paper should be taken as exploratory and preliminary. These will most likely change during a more comprehensive modeling study to be started soon with the support of the US Environmental Protection Agency. The main purpose of the present project was to obtain the initial data (emission inventories) for these regions, simulate meteorological conditions, and perform preliminary sensitivity analysis. In the future, additional regions will be simulated to assess the potential of cool cities in improving urban air quality.

  3. Lanthanum and lanthanides in atmospheric fine particles and their apportionment to refinery and petrochemical operations in Houston, TX

    NASA Astrophysics Data System (ADS)

    Kulkarni, Pranav; Chellam, Shankararaman; Fraser, Matthew P.

    A study was conducted in Houston, TX focusing on rare earth elements (REEs) in atmospheric fine particles and their sources. PM 2.5 samples were collected from an ambient air quality monitoring site (HRM3) located in the proximity of a large number of oil refineries and petrochemical industries to estimate the potential contributions of emissions from fluidized-bed catalytic cracking operations to ambient fine particulate matter. The elemental composition of ambient PM 2.5, several commercially available zeolite catalysts, and local soil was measured after microwave assisted acid digestion using inductively coupled plasma—mass spectrometry. Source identification and apportionment was performed by principal component factor analysis (PCFA) in combination with multiple linear regression. REE relative abundance sequence, ratios of La to light REEs (Ce, Pr, Nd, and Sm), and enrichment factor analysis indicated that refining and petrochemical cat cracking operations were predominantly responsible for REE enrichment in ambient fine particles. PCFA yielded five physically meaningful PM 2.5 sources: cat cracking operations, a source predominantly comprised of crustal material, industrial high temperature operations, oil combustion, and sea spray. These five sources accounted for 82% of the total mass of atmospheric fine particles (less carbon and sulfate). Factor analysis confirmed that emissions from cat cracking operations primarily contributed to REE enrichment in PM 2.5 even though they comprised only 2.0% of the apportioned mass. Results from this study demonstrate the need to characterize catalysts employed in the vicinity of the sampling stations to accurately determine local sources of atmospheric REEs.

  4. Resolving the structure of Ti3C2Tx MXenes through multilevel structural modeling of the atomic pair distribution function

    DOE PAGES

    Wesolowski, David J.; Wang, Hsiu -Wen; Page, Katharine L.; Naguib, Michael; Gogotsi, Yury

    2015-12-08

    MXenes are a recently discovered family of two-dimensional (2D) early transition metal carbides and carbonitrides, which have already shown many attractive properties and a great promise in energy storage and many other applications. However, a complex surface chemistry and small coherence length has been an obstacle in some applications of MXenes, also limiting accuracy of predictions of their properties. In this study, we describe and benchmark a novel way of modeling layered materials with real interfaces (diverse surface functional groups and stacking order between the adjacent monolayers) against experimental data. The structures of three kinds of Ti3C2Tx MXenes (T standsmore » for surface terminating species, including O, OH, and F) produced under different synthesis conditions were resolved for the first time using atomic pair distribution function obtained by high-quality neutron total scattering. The true nature of the material can be easily captured with the sensitivity of neutron scattering to the surface species of interest and the detailed third-generation structure model we present. The modeling approach leads to new understanding of MXene structural properties and can replace the currently used idealized models in predictions of a variety of physical, chemical and functional properties of Ti3C2-based MXenes. Furthermore, the developed models can be employed to guide the design of new MXene materials with selected surface termination and controlled contact angle, catalytic, optical, electrochemical and other properties. We suggest that the multi-level structural modeling should form the basis for a generalized methodology on modeling diffraction and pair distribution function data for 2D and layered materials.« less

  5. Focalyx Dx, Bx, Tx et Apps: A novel contemporary fusion paradigm for the management of prostate cancer.

    PubMed

    Bianco, F J; Martínez-Salamanca, J I

    2016-07-01

    FocalyxTM conceived as a response to emerging evidence data across numerous cancer lesions that questions current standard treatment approaches that too often lead to detrimental quality of life yet delivering limited survival benefit, especially in-lieu of advances in imaging technology applicable to cancer patients. The Focalyx paradigm aims to control cancer with improvement in quality of life. We initially devised 5 milestones: 1- Consistently optimize Prostate MRI imaging using the novel published protocols adopted as guidelines by societies such as the European Society of Urology and Radiology; 2- Evaluate fusion platform software solutions that existed; 3- Determine best fusión platform for Focalyx on practicality, precision, and workflow premises; 4- Evaluate commercially available FDA approved ablative technologies to implement our treatment vision; 5- Design a treatment option that can be performed in the office setting under local anesthesia, which would not impact negatively QOL outcomes of Prostate Cancer patients and seamless constant nonintrusive practical patient-physician interaction by the Focalyx app that facilitates follow up and provides early warning signals shall any change in the disease dynamics emerge. Prostate cancer was identified as the pilot disease for Focalyx to deliver a "GPS" like solution for the prostate gland that destroys identifiable disease without adverse effects such as: cancer anxiety, urinary incontinence, loss of erections and ejaculation. Since September of 2013, over 300 men have been accrued in NCT02381990- clintrials.gov evaluating the feasibility of our solutions for imaging (FocalyxDx), Biopsy (FocalyxBx) and Treatment (FocalyxTx). In this review we detail the tools available to achieve the Focalyx paradigm for men with Prostate Cancer.

  6. Landsliding in Allegheny County, Pennsylvania

    USGS Publications Warehouse

    Briggs, Reginald Peter; Pomeroy, John S.; Davies, William E.

    1975-01-01

    Man should proceed with caution if modifications such as loading, excavation, or changes of the water regime are contemplated for slopes in Allegheny County, especially those slopes described on the map as highly sensitive to disturbance by man. Features indicative of unstable slope conditions include: cracks in buildings, yard walls, and pools; doors and windows that jam; fences and other linear features bowed out of line; tilted trees and utility poles; cracks and steplike ground features; hummocky ground; and water seeps. Geologic factors related to the landsliding process include rock types, layering, fracturing, and attitude; nature of soil cover; permeability of rocks and soils; and steepness of slope.

  7. Geothermal development plan: Pinal county

    SciTech Connect

    White, D.H.

    1981-01-01

    Wells drilled in the county provide evidence of geothermal energy sufficient for process heat and space heating and cooling applications. Annual energy consumption was estimated for industries whose process heat requirements are less than 105/sup 0/C (221/sup 0/F). This information was then used to model the introduction of geothermal energy into the process heat market. Also, agriculture and agribusiness industries were identified. Many of these are located on or near a geothermal resource and might be able to utilize geothermal energy in their operations.

  8. Water resources of Sweetwater County, Wyoming

    USGS Publications Warehouse

    Mason, Jon P.; Miller, Kirk A.

    2004-01-01

    Sweetwater County is located in the southwestern part of Wyoming and is the largest county in the State. A study to quantify the availability and describe the chemical quality of surface-water and ground-water resources in Sweetwater County was conducted by the U.S. Geological Survey in cooperation with the Wyoming State Engineers Office. Most of the county has an arid climate. For this reason a large amount of the flow in perennial streams within the county is derived from outside the county. Likewise, much of the ground-water recharge to aquifers within the county is from flows into the county, and occurs slowly. Surface-water data were not collected as part of the study. Evaluations of streamflow and stream-water quality were limited to analyses of historical data and descriptions of previous investigations. Forty-six new ground-water-quality samples were collected as part of the study and the results from an additional 782 historical ground-water-quality samples were reviewed. Available hydrogeologic characteristics for various aquifers throughout the county also are described. Flow characteristics of streams in Sweetwater County vary substantially depending on regional and local basin characteristics and anthropogenic factors. Because precipitation amounts in the county are small, most streams in the county are ephemeral, flowing only as a result of regional or local rainfall or snowmelt runoff. Flows in perennial streams in the county generally are a result of snowmelt runoff in the mountainous headwater areas to the north, west, and south of the county. Flow characteristics of most perennial streams are altered substantially by diversions and regulation. Water-quality characteristics of selected streams in and near Sweetwater County during water years 1974 through 1983 were variable. Concentrations of dissolved constituents, suspended sediment, and bacteria generally were smallest at sites on the Green River because of resistant geologic units, increased

  9. 76 FR 28415 - Fresno County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Robbin Ekman, Fresno County Resource Advisory Committee Coordinator, c/ o Sierra National Forest, High... FURTHER INFORMATION CONTACT: Robbin Ekman, Fresno County Resource ] Advisory Committee Coordinator,...

  10. 76 FR 44302 - Fresno County Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-25

    ... Robbin Ekman, Fresno County Resource Advisory Committee Coordinator, c/ o Sierra National Forest, High... FURTHER INFORMATION CONTACT: Robbin Ekman, Fresno County Resource Advisory Committee Coordinator,...

  11. Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, Addison Branch), spanning Lemon Fair River above Richville Pond, west of East Shoreham Road, Shoreham, Addison County, VT

  12. Educational and Demographic Profile: Mendocino County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Mendocino County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  13. Geothermal development issues: Recommendations to Deschutes County

    SciTech Connect

    Gebhard, C.

    1982-07-01

    This report discusses processes and issues related to geothermal development. It is intended to inform planners and interested individuals in Deschutes County about geothermal energy, and advise County officials as to steps that can be taken in anticipation of resource development. (ACR)

  14. Latinos and Education in Ventura County.

    ERIC Educational Resources Information Center

    Segura, Denise A.

    This paper provides an overview of demographic and educational attainment data on Latinos in Ventura County, California, and describes an ongoing initiative to increase Latino college attendance through improved K-12 preparation and family involvement. In both its urban and rural areas, Ventura County harbors large Latino populations who are…

  15. Educational and Demographic Profile: Lake County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Lake County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  16. Commodity Flow Study - Clark County, Nevada, USA

    SciTech Connect

    Conway, S.Ph.D.; Navis, I.

    2008-07-01

    The United States Department of Energy has designated Clark County, Nevada as an 'Affected Unit of Local Government' due to the potential for impacts by activities associated with the Yucca Mountain High Level Nuclear Waste Repository project. Urban Transit, LLC has led a project team of transportation including experts from the University of Nevada Las Vegas Transportation Research Center to conduct a hazardous materials community flow study along Clark County's rail and truck corridors. In addition, a critical infrastructure analysis has also been carried out in order to assess the potential impacts of transportation within Clark County of high level nuclear waste and spent nuclear fuel to a proposed repository 90 miles away in an adjacent county on the critical infrastructure in Clark County. These studies were designed to obtain information relating to the transportation, identification and routing of hazardous materials through Clark County. Coordinating with the United States Department of Energy, the U.S. Department of Agriculture, the U. S. Federal Highway Administration, the Nevada Department of Transportation, and various other stakeholders, these studies and future research will examine the risk factors along the entire transportation corridor within Clark County and provide a context for understanding the additional vulnerability associated with shipping spent fuel through Clark County. (authors)

  17. Educational and Demographic Profile: San Benito County.

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Benito County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  18. Public Library Service for San Benito County.

    ERIC Educational Resources Information Center

    McGovern, Gail

    A sparsely populated, agricultural area, San Benito County (California) provides library services in conjunction with the Hollister city library and in cooperation with the San Juan Bautista city library. Financing comes from the county general fund. There are no written goals or policy statements and no professionally trained librarians. As…

  19. Groundwater management and protection Madison County, Alabama

    SciTech Connect

    French, J.H.; Strunk, J.W.

    1990-07-01

    Groundwater is extremely important to Madison County as it provides nearly three quarters of the county's drinking water. In recent years, Madison County has increasingly recognized the need to protect its groundwater resource. A supply of usable groundwater is one element of a high quality environment, which can help spur economic development and provide for the needs of a growing population. Without planning protection and understanding of possible consequences, however, economic development and population pressures can cause a gradual degradation of groundwater. In April 1987, the Tennessee Valley Authority (TVA) convened a local groundwater steering group in Madison County. At the first meeting the ground agreed upon these goals: (1) to seek incorporate groundwater protection into the planning and development process for Madison County, (2) to support efforts by Madison County to obtain authority to adopt zoning ordinances and subdivision regulations, and (3) to develop a groundwater management plan for the county. This report provides essential information needed in developing a plan and is based on the following assumptions: the citizens of Madison County value the environment in which they live and wish to protect it from pollution; continued economic development is necessary for a healthy local economy; and a healthy economy can be sustained and nurtured, without degradation of the groundwater resource, through countywide planning, education, and participation.

  20. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  1. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  2. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  3. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  4. 24 CFR 570.307 - Urban counties.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... activities, specifically urban renewal and publicly assisted housing. In determining whether a county has the... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Urban counties. 570.307 Section 570.307 Housing and Urban Development Regulations Relating to Housing and Urban Development...

  5. A Rural County's Response to Homelessness.

    ERIC Educational Resources Information Center

    Loughran, Elizabeth Lee; White, Priscilla

    This paper describes the response of one locality, a rural county in Western Massachusetts, to the reality of rural homelessness. Jessie's House, in Hampshire County, Massachusetts, is a short-term emergency shelter providing meals, housing, and advocacy to homeless families and individuals. The shelter has a staff of three full-time residents and…

  6. Analysis of County School Districts in Arkansas.

    ERIC Educational Resources Information Center

    Budd, Karol B.; Charlton, J.L.

    The 1948, Arkansas School District Reorganization Act was passed in an effort to reduce the 1589 small school districts to a smaller number. Those districts not consolidated would form county districts. As of the 1967-68 school year, 26 of these county districts remained. The purpose of this study was to provide information drawing attention to…

  7. Socioeconomic Heterogeneity of Mining-Dependent Counties.

    ERIC Educational Resources Information Center

    Nord, Mark; Luloff, A. E.

    1993-01-01

    Although the socioeconomic well-being of all U.S. mining-dependent counties was slightly above the national average in 1990, disaggregation reveals substantial effects of region and mining subsector. In particular, southern and Great Lakes coal-mining counties had significantly lower high school graduation rates and higher poverty and unemployment…

  8. A Profile of Anson County, North Carolina.

    ERIC Educational Resources Information Center

    Farr, M. Gaston; And Others

    Since 1950 Anson County, North Carolina, has had major contributions to economic development, a source of great concern to residents of the almost entirely rural area. The increased capacity of the Blewitt Falls Dam power output and the county-wide water filtration system (one of only a few in the United States today) are attractive to industry.…

  9. [A Profile of Kershaw County, South Carolina].

    ERIC Educational Resources Information Center

    Lilley, Stephen C.; McLean, Edward L.

    Careful long-range planning and slow, deliberate growth have benefitted Kershaw County's 500,000 pleasantly varied acres near the state capitol. The county, famous for its equestrian activity, boasts prestige stables, riding clubs, and trails. In addition there are lakes and numerous parks. Leaders want to maintain this aesthetic appeal while…

  10. A Profile of Hardee County, Florida.

    ERIC Educational Resources Information Center

    Beaulieu, Lionel J.; Anderson, Deborah S.

    In 1977 leaders of Hardee County, Florida, listed relationships and attitudes of residents, rural atmosphere, environmental conditions, and economic potential among the county's strong points, and public service and facility improvements, developing economic potential, recreational and entertainment development, and planning and zoning as its most…

  11. Educational and Demographic Profile: Yolo County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for Yolo County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced communication…

  12. The Farm Crisis and Decatur County.

    ERIC Educational Resources Information Center

    Flora, Jan L.; And Others

    This case study assesses the impact of the farm sector on the economy and social organization of Decatur County (Kansas), a county which has historically depended on agriculture for its livelihood. Data were obtained from analysis of time series statistical indicators for the period between 1966 and 1984, questionnaire responses of local…

  13. Educational and Demographic Profile: San Joaquin County

    ERIC Educational Resources Information Center

    California Postsecondary Education Commission, 2004

    2004-01-01

    This profile uniquely presents a variety of educational and socioeconomic information for San Joaquin County, nearby counties, and the state. The profile highlights the relationship between various factors that affect the economic well-being of individuals and communities. This presentation of information provides a framework for enhanced…

  14. Geothermal development plan: Yuma County

    NASA Astrophysics Data System (ADS)

    White, D. H.; Goldstone, L. A.

    1982-08-01

    The potential for utilizing geothermal energy was evaluated. Four potential geothermal resource areas with temperatures less than 900C (1940F) were identified, and in addition, two areas are inferred to contain geothermal resources with intermediate temperature potential. The resource areas are isolated. One resource site contains a hot dry rock resource. Anticipated population growth in the county is expected to be 2% per year over the next 40 years. The primary employment sector is agriculture, though some light industry is located in the county. Water supplies are found to be adequate to support future growth without adverse affect on agriculture. In addition, several agricultural processors were found, concentrated in citrus processing and livestock raising. It is suggested that by the year 2000, geothermal energy may economically provide the energy equivalent of 53,000 barrels of oil per year to the industrial sector if developed privately. Geothermal utilization projections increase to 132,000 barrels of oil per year by 2000 if a municipal utility developed the resource.

  15. Family planning in Nangong County.

    PubMed

    Sun, X

    1980-04-01

    Family planning has been practiced in Nangong county, China, since 1971; as a result the population growth rate has dropped from 16.7/1000 to 3.6/1000 in 1979; 98% of women of childbearing age use contraception, and most couples have only 1 child. Before 1971 most couples had 4-5 children; per capita grain rations had to be reduced because of the increase in population, and more grain had to be supplied by the state. 1 child families are now rewarded with an annual monetary bonus, extra grain allocations for the child, free tuition in schools, and preference in job placement and medical treatment. Parents who have more than 2 children are penalized by the withdrawal of 10% of their monthly earnings. The idea of "1 couple 1 child" is a radical change from China's traditional culture, which viewed children especially sons, as an insurance against old age insecurity. Marriage at a later age is also encouraged; in Nangong county none of the men of marriageable age married before 25, and none of the women before 23. As a result of promoting family planning Nangong country has ceased to need grain subsidies from the state, and in recent years has had a 10,000 ton surplus to sell.

  16. Family planning in Nangong County.

    PubMed

    Sun, X

    1980-04-01

    Family planning has been practiced in Nangong county, China, since 1971; as a result the population growth rate has dropped from 16.7/1000 to 3.6/1000 in 1979; 98% of women of childbearing age use contraception, and most couples have only 1 child. Before 1971 most couples had 4-5 children; per capita grain rations had to be reduced because of the increase in population, and more grain had to be supplied by the state. 1 child families are now rewarded with an annual monetary bonus, extra grain allocations for the child, free tuition in schools, and preference in job placement and medical treatment. Parents who have more than 2 children are penalized by the withdrawal of 10% of their monthly earnings. The idea of "1 couple 1 child" is a radical change from China's traditional culture, which viewed children especially sons, as an insurance against old age insecurity. Marriage at a later age is also encouraged; in Nangong county none of the men of marriageable age married before 25, and none of the women before 23. As a result of promoting family planning Nangong country has ceased to need grain subsidies from the state, and in recent years has had a 10,000 ton surplus to sell. PMID:12264032

  17. Imperial County geothermal development annual meeting: summary

    SciTech Connect

    Not Available

    1983-01-01

    All phases of current geothermal development in Imperial County are discussed and future plans for development are reviewed. Topics covered include: Heber status update, Heber binary project, direct geothermal use for high-fructose corn sweetener production, update on county planning activities, Brawley and Salton Sea facility status, status of Imperial County projects, status of South Brawley Prospect 1983, Niland geothermal energy program, recent and pending changes in federal procedures/organizations, plant indicators of geothermal fluid on East Mesa, state lands activities in Imperial County, environmental interests in Imperial County, offshore exploration, strategic metals in geothermal fluids rebuilding of East Mesa Power Plant, direct use geothermal potential for Calipatria industrial Park, the Audubon Society case, status report of the Cerro Prieto geothermal field, East Brawley Prospect, and precision gravity survey at Heber and Cerro Prieto geothermal fields. (MHR)

  18. Water resources of Duval County, Florida

    USGS Publications Warehouse

    Phelps, G.G.

    1994-01-01

    The report describes the hydrology and water resources of Duval County, the development of its water supplies, and water use within the county. Also included are descriptions of various natural features of the county (such as topography and geology), an explanation of the hydrologic cycle, and an interpretation of the relationship between them. Ground-water and surface-water resources and principal water-quality features within the county are also discussed. The report is intended to provide the general public with an overview of the water resources Of Duval County, and to increase public awareness of water issues. Information is presented in nontechnical language to enable the general reader to understand facts about water as a part of nature, and the problems associated with its development and use.

  19. Environmental assessment: Deaf Smith County site, Texas

    SciTech Connect

    Not Available

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified a location in Deaf Smith County, Texas, as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Deaf Smith County site and the eight other potentially sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. The Deaf Smith County site is in the Permian Basin, which is one of five distinct geohydrologic settings considered for the first repository. On the basis of the evaluations reported in this EA, the DOE has found that the Deaf Smith County site is not disqualified under the guidelines. On the basis of these findings, the DOE is nominating the Deaf Smith County site as one of the five sites suitable for characterization. 591 refs., 147 figs., 173 tabs.

  20. Feasibility of using Geant4 Monte Carlo simulation for IMRT dose calculations for the Novalis Tx with a HD-120 multi-leaf collimator

    NASA Astrophysics Data System (ADS)

    Jung, Hyunuk; Shin, Jungsuk; Chung, Kwangzoo; Han, Youngyih; Kim, Jinsung; Choi, Doo Ho

    2015-05-01

    The aim of this study was to develop an independent dose verification system by using a Monte Carlo (MC) calculation method for intensity modulated radiation therapy (IMRT) conducted by using a Varian Novalis Tx (Varian Medical Systems, Palo Alto, CA, USA) equipped with a highdefinition multi-leaf collimator (HD-120 MLC). The Geant4 framework was used to implement a dose calculation system that accurately predicted the delivered dose. For this purpose, the Novalis Tx Linac head was modeled according to the specifications acquired from the manufacturer. Subsequently, MC simulations were performed by varying the mean energy, energy spread, and electron spot radius to determine optimum values of irradiation with 6-MV X-ray beams by using the Novalis Tx system. Computed percentage depth dose curves (PDDs) and lateral profiles were compared to the measurements obtained by using an ionization chamber (CC13). To validate the IMRT simulation by using the MC model we developed, we calculated a simple IMRT field and compared the result with the EBT3 film measurements in a water-equivalent solid phantom. Clinical cases, such as prostate cancer treatment plans, were then selected, and MC simulations were performed. The accuracy of the simulation was assessed against the EBT3 film measurements by using a gamma-index criterion. The optimal MC model parameters to specify the beam characteristics were a 6.8-MeV mean energy, a 0.5-MeV energy spread, and a 3-mm electron radius. The accuracy of these parameters was determined by comparison of MC simulations with measurements. The PDDs and the lateral profiles of the MC simulation deviated from the measurements by 1% and 2%, respectively, on average. The computed simple MLC fields agreed with the EBT3 measurements with a 95% passing rate with 3%/3-mm gamma-index criterion. Additionally, in applying our model to clinical IMRT plans, we found that the MC calculations and the EBT3 measurements agreed well with a passing rate of greater

  1. Fayette County Better Buildings Initiative

    SciTech Connect

    Capella, Arthur

    2015-03-04

    The Fayette County Better Buildings Initiative represented a comprehensive and collaborative approach to promoting and implementing energy efficiency improvements. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. The ultimate goal of Fayette County’s Better Buildings Initiative was to implement a total of 1,067 residential energy efficiency retrofits with a minimum 15% estimated energy efficiency savings per unit. Program partners included: United States Department of Energy, Allegheny Power, and Private Industry Council of Westmoreland-Fayette, Fayette County Redevelopment Authority, and various local partners. The program was open to any Fayette County residents who own their home and meet the prequalifying conditions. The level of assistance offered depended upon household income and commitment to undergo a BPI – Certified Audit and implement energy efficiency measures, which aimed to result in at least a 15% reduction in energy usage. The initiative was designed to focus on implementing energy efficiency improvements in residential units, while simultaneously supporting general marketing of the benefits of implementing energy efficiency measures. Additionally, the program had components that involved recruitment and training for employment of persons in the energy sector (green jobs), as well as marketing and implementation of a commercial or community facilities component. The residential component of Fayette County’s Better Buildings Initiative involved a comprehensive approach, providing assistance to low- moderate- and market-rate homeowners. The initiative will also coordinate activities with local utility providers to further incentivize energy efficiency improvements among qualifying homeowners. The commercial component of Fayette County’s Better Building Initiative involved grants

  2. SU-E-J-48: Imaging Origin-Radiation Isocenter Coincidence for Linac-Based SRS with Novalis Tx

    SciTech Connect

    Geraghty, C; Workie, D; Hasson, B

    2015-06-15

    Purpose To implement and evaluate an image-based Winston-Lutz (WL) test to measure the displacement between ExacTrac imaging origin and radiation isocenter on a Novalis Tx system using RIT V6.2 software analysis tools. Displacement between imaging and radiation isocenters was tracked over time. The method was applied for cone-based and MLC-based WL tests. Methods The Brainlab Winston-Lutz phantom was aligned to room lasers. The ExacTrac imaging system was then used to detect the Winston- Lutz phantom and obtain the displacement between the center of the phantom and the imaging origin. EPID images of the phantom were obtained at various gantry and couch angles and analyzed with RIT calculating the phantom center to radiation isocenter displacement. The RIT and Exactrac displacements were combined to calculate the displacement between imaging origin and radiation isocenter. Results were tracked over time. Results Mean displacements between ExacTrac origin and radiation isocenter were: VRT: −0.1mm ± 0.3mm, LNG: 0.5mm ± 0.2mm, LAT: 0.2mm ± 0.2mm (vector magnitude of 0.7 ± 0.2mm). Radiation isocenter was characterized by the mean of the standard deviations of the WL phantom displacements: σVRT: 0.2mm, σLNG: 0.4mm, σLAT: 0.6mm. The linac couch base was serviced to reduce couch walkout. This reduced σLAT to 0.2mm. These measurements established a new baseline of radiation isocenter-imaging origin coincidence. Conclusion The image-based WL test has ensured submillimeter localization accuracy using the ExacTrac imaging system. Standard deviations of ExacTrac-radiation isocenter displacements indicate that average agreement within 0.3mm is possible in each axis. This WL test is a departure from the tradiational WL in that imaging origin/radiation isocenter agreement is the end goal not lasers/radiation isocenter.

  3. Nolley v. County of Erie.

    PubMed

    1991-10-31

    The U.S. District Court, Western District of New York, held that the Erie County Holding Center (ECHC) had violated an HIV-positive inmate's privacy rights under the U.S. Constitution and the New York Public Health Law by placing red stickers on the inmate's paperwork and belongings, and by segregating her from the general inmate population. The court reasoned that, pursuant to the federal Centers for Disease Control's recommendation that corrections staff take HIV precautions with all inmates, the ECHC's treatment constituted an unjustifiable isolation based solely on her HIV status. The court also held that the ECHC further violated the inmate's constitutional rights by denying her access to the law library and to religious services. Although the court found the inmate's incarceration conditions "deplorable," the conditions did not constitute "cruel and unusual punishment." The court also found no federal Rehabilitation Act violation because the ECHC did not receive federal financial assistance.

  4. Hydrologic conditions: Dade County, Florida

    USGS Publications Warehouse

    Kohout, Francis Anthony; Klein, Howard; Sherwood, C.B.; Leach, Stanley D.

    1964-01-01

    Thin layers of dense limestone of low permeability that occur near the top of the Biscayne aquifer in the vicinity of the north end of Levee 30 in Dade County, Florida are of hydrologic importance because they retard the downward infiltration of ponded water in Conservation Area No. 3. This retarding effect frequently results in high head differentials across the levee. Tests made in a small area adjacent to Levee 30 indicate that the coefficient of transmissibility of the aquifer is 3,600,000 gpd (gallons per day) per foot, and the coefficient of vertical permeability of the dense limestones is 13 gpd per square foot. If ground-water flow beneath the levee is laminar, the total inflow to the Levee 30 Canal from Conservation Area No. 3 will be about 350 mgd (million gallons per day), or 540 cfs (cubic feet per second), per mile length of levee when the head difference across the levee is 10 feet.

  5. Costilla County Biodiesel Pilot Project

    SciTech Connect

    Doon, Ben; Quintana, Dan

    2011-08-25

    The Costilla County Biodiesel Pilot Project has demonstrated the compatibility of biodiesel technology and economics on a local scale. The project has been committed to making homegrown biodiesel a viable form of community economic development. The project has benefited by reducing risks by building the facility gradually and avoiding large initial outlays of money for facilities and technologies. A primary advantage of this type of community-scale biodiesel production is that it allows for a relatively independent, local solution to fuel production. Successfully using locally sourced feedstocks and putting the fuel into local use emphasizes the feasibility of different business models under the biodiesel tent and that there is more than just a one size fits all template for successful biodiesel production.

  6. Computer Technology in Rural Schools: The Case of Mendocino County.

    ERIC Educational Resources Information Center

    Hoachlander, E. Gareth

    The county education office of Mendocino County, California, serving nine school districts and 11,800 elementary and secondary students, began planning for computers in 1979-1980, purchased two central computers, and by 1983 had one computer or terminal for every 40 students in the county. The county was characterized by its very enthusiastic…

  7. Evaluation of the Union County Alternative to Suspension Program

    ERIC Educational Resources Information Center

    Dunlap, Joyce Ann

    2010-01-01

    The schools in Union County have undergone a tremendous amount of growth in the past decade. The growth in the county has led to an increase in discipline problems. In order to provide suspended students a second chance, Union County Public Schools implemented an alternative to suspension program, the Union County Alternative to Suspension Program…

  8. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  9. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  10. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  11. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  12. 7 CFR 760.902 - Eligible counties and disaster periods.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Eligible counties and disaster periods. 760.902... § 760.902 Eligible counties and disaster periods. Counties are eligible for agricultural assistance..., 2005, and before February 28, 2007. Eligible counties, disaster events, and disaster periods are...

  13. 7 CFR 1230.634 - FSA county office report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CONSUMER INFORMATION Procedures for the Conduct of Referendum Referendum § 1230.634 FSA county office report. The FSA county office will notify the FSA State office of the results of the referendum. Each FSA county office will transmit the results of the referendum in its county to the FSA State office....

  14. 7 CFR 1230.634 - FSA county office report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CONSUMER INFORMATION Procedures for the Conduct of Referendum Referendum § 1230.634 FSA county office report. The FSA county office will notify the FSA State office of the results of the referendum. Each FSA county office will transmit the results of the referendum in its county to the FSA State office....

  15. 1918 Influenza: A Winnebago County, Wisconsin Perspective

    PubMed Central

    Shors, Teri; McFadden, Susan H.

    2009-01-01

    The population of Winnebago County in 1918 was approximately 62,000 residents. It consisted of towns supporting diverse manufacturers surrounded by farming country. For this study, records were revisited, and 1918 to 1920 influenza survivors were interviewed. A pharmacological investigation encompassing the various influenza treatments used in Wisconsin from 1918 to 1920 was documented. In 1918, over 180 individuals perished from influenza, and over 2000 cases were reported in Winnebago County, Wisconsin. Influenza returned in 1920, which some researchers refer to as the “fourth wave,” claiming nearly 50 lives in Winnebago County, Wisconsin. This study also documents the 1920 influenza wave. PMID:19889943

  16. Drainage basins in Duval County, Florida

    USGS Publications Warehouse

    Stone, Roy B.; Largen, Joseph B.

    1983-01-01

    The drainage basins and subbasins in Duval County, Florida, are delineated on this atlas map. The county 's 840 square-mile area is drained by three major river systems; the St. Johns, 668 square miles; Nassau, 113 square miles; and St. Marys, 59 square miles. The remainder of the county is drained by a network of small streams that flow into either the Intracoastal Waterway or directly into the Atlantic Ocean. The sub-basins range in size from less than one square mile to more than 50 square miles. (USGS)

  17. Tri-county pilot study. [Texas

    NASA Technical Reports Server (NTRS)

    Reeves, C. A. (Principal Investigator); Austin, T. W.; Kerber, A. G.

    1976-01-01

    The author has identified the following significant results. An area inventory was performed for three southeast Texas counties (Montgomery, Walker, and San Jacinto) totaling 0.65 million hectares. The inventory was performed using a two level hierarchy. Level 1 was divided into forestland, rangeland, and other land. Forestland was separated into Level 2 categories: pine, hardwood, and mixed; rangeland was not separated further. Results consisted of area statistics for each county and for the entire study site for pine, hardwood, mixed, rangeland, and other land. Color coded county classification maps were produced for the May data set, and procedures were developed and tested.

  18. County/private partnership expedites recycling

    SciTech Connect

    Not Available

    1994-03-01

    This article describes how Broward County, Florida and Browning-Ferris Industries (Houston, Texas) implemented a highly accelerated recycling project that had a county-wide recycling system fully operational in 180 days. The program is a strong step toward speeding compliance with Florida's mandated 30 percent recycling goal. The 1.2 million citizens in Broward County began recycling materials in dual curbside bins October 1, 1993. Previously, the participating communities all acted autonomously. Minimal volumes of newspaper, aluminum, clear glass, and some plastic were collected by curbsort vehicles and processed at small local recycling centers.

  19. Lea County 001, an H5 chondrite, and Lea County 002, an ungrouped type 3 chondrite

    SciTech Connect

    Zolensky, M.E.; Score, R.; Clayton, R.N.; Mayeda, T.K.; Schutt, J.W. Lockheed Engineering and Sciences Co., Houston, TX Chicago Univ., IL )

    1989-12-01

    A search of active deflation basins near Jal, Lea County, New Mexico resulted in the discovery of two meteorites, Lea County 001 and 002. Lea County 001 has mean olivine and low-Ca pyroxene compositions of Fa(19) and Fs(17), respectively. These and all other mineralogical and petrological data collected indicate a classification of H5 for this stone. Lea County 002 has mean olivine and low-Ca pyroxene compositions of Fa(2) and Fs(4), and is unequilibrated. Although it is mineralogically most similar to Kakangari and chondritic clasts within Cumberland Falls, the high modal amount of forsterite makes Lea County a unique type 3 chondrite. Oxygen isotope data for Lea County 002 fall on an 0-16-mixing line through those of the enstatite meteorites and IAB irons, a feature shared by Kakangari. 28 refs.

  20. Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1

    PubMed Central

    Joeres, Niko; Augustinowski, Katrin; Neuhof, Andreas; Assmann, Marc; Gründer, Stefan

    2016-01-01

    Acid Sensing Ion Channels (ASICs) detect extracellular proton signals and are involved in synaptic transmission and pain sensation. ASIC subunits assemble into homo- and heteromeric channels composed of three subunits. Single molecule imaging revealed that heteromers composed of ASIC1a and ASIC2a, which are widely expressed in the central nervous system, have a flexible 2:1/1:2 stoichiometry. It was hitherto not possible, however, to functionally differentiate these two heteromers. To have a homogenous population of ASIC1a/2a heteromers with either 2:1 or 1:2 stoichiometry, we covalently linked subunits in the desired configuration and characterized their functional properties in Xenopus oocytes. We show that the two heteromers have slightly different proton affinity, with an additional ASIC1a subunit increasing apparent affinity. Moreover, we found that zinc, which potentiates ASIC2a-containing ASICs but not homomeric ASIC1a, potentiates both heteromers. Finally, we show that PcTx1, which binds at subunit-subunit interfaces of homomeric ASIC1a, inhibits both heteromers suggesting that ASIC2a can also contribute to a PcTx1 binding site. Using this functional fingerprint, we show that rat cortical neurons predominantly express the ASIC1a/2a heteromer with a 2:1 stoichiometry. Collectively, our results reveal the contribution of individual subunits to the functional properties of ASIC1a/2a heteromers. PMID:27277303

  1. Characterization of Vadose Zone Sediments Below the TX Tank Farm: Boreholes C3830, C3831, C3832 and RCRA Borehole 299-W10-27

    SciTech Connect

    Serne, R. Jeffrey; Bjornstad, Bruce N.; Horton, Duane G.; Lanigan, David C.; Lindenmeier, Clark W.; Lindberg, Michael J.; Clayton, Ray E.; Legore, Virginia L.; Orr, Robert D.; Kutnyakov, Igor V.; Baum, Steven R.; Geiszler, Keith N.; Valenta, Michelle M.; Vickerman, Tanya S.

    2008-09-11

    This report was revised in September 2008 to remove acid-extractable sodium data from Tables 4.8, 4.28,4.43, and 4.59. The sodium data was removed due to potential contamination introduced during the acid extraction process. The rest of the text remains unchanged from the original report issued in April 2004. The overall goal of the Tank Farm Vadose Zone Project, led by CH2M HILL Hanford Group, Inc., is to define risks from past and future single-shell tank farm activities at Hanford. To meet this goal, CH2M HILL Hanford Group, Inc. tasked scientists from Pacific Northwest National Laboratory to perform detailed analyses on vadose zone sediments from within Waste Management Area (WMA) T-TX-TY. This report is the first of two reports written to present the results of these analyses. Specifically, this report contains all the geologic, geochemical, and selected physical characterization data collected on vadose zone sediment recovered from boreholes C3830, C3831, and C3832 in the TX Tank Farm, and from borehole 299-W-10-27 installed northeast of the TY Tank Farm.

  2. Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1.

    PubMed

    Joeres, Niko; Augustinowski, Katrin; Neuhof, Andreas; Assmann, Marc; Gründer, Stefan

    2016-01-01

    Acid Sensing Ion Channels (ASICs) detect extracellular proton signals and are involved in synaptic transmission and pain sensation. ASIC subunits assemble into homo- and heteromeric channels composed of three subunits. Single molecule imaging revealed that heteromers composed of ASIC1a and ASIC2a, which are widely expressed in the central nervous system, have a flexible 2:1/1:2 stoichiometry. It was hitherto not possible, however, to functionally differentiate these two heteromers. To have a homogenous population of ASIC1a/2a heteromers with either 2:1 or 1:2 stoichiometry, we covalently linked subunits in the desired configuration and characterized their functional properties in Xenopus oocytes. We show that the two heteromers have slightly different proton affinity, with an additional ASIC1a subunit increasing apparent affinity. Moreover, we found that zinc, which potentiates ASIC2a-containing ASICs but not homomeric ASIC1a, potentiates both heteromers. Finally, we show that PcTx1, which binds at subunit-subunit interfaces of homomeric ASIC1a, inhibits both heteromers suggesting that ASIC2a can also contribute to a PcTx1 binding site. Using this functional fingerprint, we show that rat cortical neurons predominantly express the ASIC1a/2a heteromer with a 2:1 stoichiometry. Collectively, our results reveal the contribution of individual subunits to the functional properties of ASIC1a/2a heteromers. PMID:27277303

  3. Characteristics of the Las Vegas/Clark County visitor economy

    SciTech Connect

    1988-06-01

    The purpose of this report is to present the results of a review of the Clark County visitor economy and the Clark County visitor. The review, undertaken in support of NWPO`s two objectives mentioned above, addressed a number of topics including performance of the Clark County visitor economy as a generator of employment, earnings and tax base; importance of the Clark County visitor economy to the Nevada economy as a whole; elements of the Clark County visitor economy outside the Las Vegas strip and downtown areas; current trends in the Clark County visitor industry; and indirect economic effects of Clark County casino/hotel purchases.

  4. 78 FR 60686 - Establishment of the Big Valley District-Lake County and Kelsey Bench-Lake County Viticultural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... on April 5, 2013 (78 FR 20544), proposing to establish the Big Valley District-Lake County and Kelsey... District-Lake County and Kelsey Bench-Lake County Viticultural Areas and Modification of the Red Hills Lake... approximately 11,000-acre ``Big Valley District-Lake County'' viticultural area and the approximately...

  5. 76 FR 30152 - East Calloway County Middle School Mercury Spill Site, Murray, Calloway County, KY; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... AGENCY East Calloway County Middle School Mercury Spill Site, Murray, Calloway County, KY; Notice of... response costs concerning the East Calloway County Middle School Mercury Spill Site located in Murray... Site name East Calloway County ] Middle School Mercury Spill Site by one of the following methods:...

  6. 75 FR 49016 - County of Greenville, S.C.-Acquisition Exemption-Greenville County Economic Development Corporation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Greenville County Economic Development Corporation (GCEDC) approximately 11.8 miles of rail line between... accordance with the National Trails System Act, 16 U.S.C. 1247(d). See Greenville County Economic Development... Surface Transportation Board County of Greenville, S.C.--Acquisition Exemption--Greenville County...

  7. 69. MISSISSIPPI, LOWNDES CO. COLUMBUS MAP OF LOWNDES COUNTY, 1931 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    69. MISSISSIPPI, LOWNDES CO. COLUMBUS MAP OF LOWNDES COUNTY, 1931 ROAD MAP OF LOWNDES COUNTY, MISSISSIPPI, 1931 by C.L. Wood, the county engineer. Updated through the mid-1930s to show new federal aid-state roads. Compares modern system with older county system. Original scale: 1 in. to 1 mi. Property of Helen (Mrs. Sam L.) Crawford, Hamilton, Ms. Sarcone Photography, Columbus, Ms., Sep 1978. - Bridges of the Upper Tombigbee River Valley, Columbus, Lowndes County, MS

  8. Multipurpose Centers in a Rural County.

    ERIC Educational Resources Information Center

    Norris, Jean

    1978-01-01

    Describes services, programs, and funding for the various senior centers in Frankin County, New York, which has a predominately rural, low-income population. Services include bus transportation, nutrition programs, health and financial assistance, and social events. (MF)

  9. Model county ordinance for wind projects

    SciTech Connect

    Bain, D.A.

    1997-12-31

    Permitting is a crucial step in the development cycle of a wind project and permits affect the timing, cost, location, feasibility, layout, and impacts of wind projects. Counties often have the lead responsibility for permitting yet few have appropriate siting regulations for wind projects. A model ordinance allows a county to quickly adopt appropriate permitting procedures. The model county wind ordinance developed for use by northwest states is generally applicable across the country and counties seeking to adopt siting or zoning regulations for wind will find it a good starting place. The model includes permitting procedures for wind measurement devices and two types of wind systems. Both discretionary and nondiscretionary standards apply to wind systems and a conditional use permit would be issued. The standards, criteria, conditions for approval, and process procedures are defined for each. Adaptation examples for the four northwest states are provided along with a model Wind Resource Overlay Zone.

  10. Surface-water availability, Tuscaloosa County, Alabama

    USGS Publications Warehouse

    Knight, Alfred L.; Davis, Marvin E.

    1975-01-01

    The average annual runoff, about 1,270 mgd (million gallons per day), originating in Tuscaloosa County is equivalent to 20 inches or 0.95 mgd per square mile. The Black Warrior and Sipsey Rivers, the largest streams in the county, have average flows of 5,230 mgd and 580 mgd, respectively, where they leave the county, and median annual 7-day low flows in excess of 150 mgd and 35 mgd, respectively. North River, Big Sandy Creek, and Hurricane Creek have average flows in excess of 100 mgd and median annual 7-day low flows in excess of 2 mgd. Surface water generally contains less than 100 mg/l (milligrams per liter) dissolved solids, less than 10 mg/l chloride, and is soft to moderately hard. Streams having the higher hardness and the higher dissolved-solids content are in eastern Tuscaloosa County.

  11. Charging Up in King County, Washington

    ScienceCinema

    Constantine, Dow; Oliver, LeAnn; Inslee, Jay; Sahandy, Sheida; Posthuma, Ron; Morrison, David

    2016-07-12

    King County, Washington is spearheading a regional effort to develop a network of electric vehicle charging stations. It is also improving its vehicle fleet and made significant improvements to a low-income senior housing development.

  12. Environmental assessment: Deaf Smith County site, Texas

    SciTech Connect

    Not Available

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified a location in Deaf Smith County, Texas, as one of the nine potentially acceptable sites for mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Deaf Smith County site and eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. The Deaf Smith County site is in the Permian Basin, which is one of five distinct geohydrologic settings considered for the first repository. On the basis of the evaluations reported in this EA, the DOE has found that the Deaf Smith County site is not disqualified under the guidelines.

  13. Charging Up in King County, Washington

    SciTech Connect

    Constantine, Dow; Oliver, LeAnn; Inslee, Jay; Sahandy, Sheida; Posthuma, Ron; Morrison, David

    2011-01-01

    King County, Washington is spearheading a regional effort to develop a network of electric vehicle charging stations. It is also improving its vehicle fleet and made significant improvements to a low-income senior housing development.

  14. A Seniors' Program for Beaver County

    ERIC Educational Resources Information Center

    Taylor, Donald F.

    1973-01-01

    Programs for seniors are needed, according to the assistant director of continuing education at the Community College of Beaver County (Pennsylvania); the question revolves around who will pay. (Editor)

  15. 7 CFR 718.8 - Administrative county.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING QUOTAS, ACREAGE ALLOTMENTS, AND PRODUCTION ADJUSTMENT PROVISIONS APPLICABLE TO MULTIPLE PROGRAMS... located in the county where the principal dwelling is situated, or where the major portion of the farm...

  16. Environmental assessment, Deaf Smith County site, Texas

    SciTech Connect

    Not Available

    1986-05-01

    The Nuclear Waste Policy Act of 1982 (42 USC sections 10101-10226) requires the environmental assessment of a proposed site to include a statement of the basis for nominating a site as suitable for characterization. Volume 2 provides a detailed statement evaluating the site suitability of the Deaf Smith County Site under DOE siting guidelines, as well as a comparison of the Deaf Smith County Site to the other sites under consideration. The evaluation of the Deaf Smith County Site is based on the impacts associated with the reference repository design, but the evaluation will not change if based on the Mission Plan repository concept. The second part of this document compares the Deaf Smith County Site to Davis Canyon, Hanford, Richton Dome and Yucca Mountain. This comparison is required under DOE guidelines and is not intended to directly support subsequent recommendation of three sites for characterization as candidate sites. 259 refs., 29 figs., 66 refs. (MHB)

  17. Hydrogeology of Cibola County, New Mexico

    USGS Publications Warehouse

    Baldwin, J.A.; Rankin, D.R.

    1995-01-01

    The hydrogeology of Cibola County, New Mexico, was evaluated to determine the occurrence, availability, and quality of ground-water resources. Rocks of Precambrian through Quaternary age are present in Cibola County. Most rocks are sedimentary in origin except for Precambrian igneous and metamorphic rocks exposed in the Zuni Uplift and Tertiary and Quaternary basalts in northern and central parts of the county. The most productive aquifers in the county include (youngest to oldest) Quaternary deposits, sandstones in the Mesaverde Group, the Dakota-Zuni-Bluff aquifer, the Westwater Canyon aquifer, the Todilto- Entrada aquifer, sandstone beds in the Chinle Formation, and the San Andres-Glorieta aquifer. Unconsolidated sand, silt, and gravel form a mantle ranging from a few inches to 150 to 200 feet over much of the bedrock in Cibola County. Well yields range from 5 to 1,110 gallons per minute. Dissolved-solids concentrations of ground water range from 200 to more than 5,200 milligrams per liter. Calcium, magnesium, bicarbonate, and sulfate are the predominant ions in ground water in alluvial material. The Mesaverde Group mainly occurs in three areas of the county. Well yields range from less than 1 to 12 gallons per minute. The predominant ions in water from wells in the Mesaverde Group are calcium, sodium, and bicarbonate. The transition from calcium-predominant to sodium-predominant water in the southwestern part of the county likely is a result of ion exchange. Wells completed in the Dakota-Zuni-Bluff aquifer yield from 1 to 30 gallons per minute. Dissolved-solids concentrations range from 220 to 2,000 milligrams per liter in water from 34 wells in the western part of the county. Predominant ions in the ground water include calcium, sodium, sulfate, and bicarbonate. Calcium predominates in areas where the aquifer is exposed at the surface or is overlain with alluvium. Sandstones in the Chinle Formation yield from 10 to 300 gallons per minute to wells in the Grants

  18. SOLAR PANELS ON HUDSON COUNTY FACILITIES

    SciTech Connect

    BARRY, KEVIN

    2014-06-06

    This project involved the installation of an 83 kW grid-connected photovoltaic system tied into the energy management system of Hudson County's new 60,000 square foot Emergency Operations and Command Center and staff offices. Other renewable energy features of the building include a 15 kW wind turbine, geothermal heating and cooling, natural daylighting, natural ventilation, gray water plumbing system and a green roof. The County intends to seek Silver LEED certification for the facility.

  19. The Water Cycle in Volusia County

    USGS Publications Warehouse

    German, Edward R.

    2009-01-01

    Earth's water is always in motion. The water cycle, also known as the hydrologic cycle, describes the continuous movement of water on, above, and below the Earth's surface. This fact sheet provides information about how much water moves into and out of Volusia County, and where it is stored. It also illustrates the seasonal variation in water quantity and movement using data from some of the hydrologic data collection sites in or near Volusia County, Florida.

  20. DOE/EPRI hybrid power system

    SciTech Connect

    Stiger, S.G.; Taylor, K.J.; Hughes, E.E.

    1988-01-01

    One of the primary objectives of the DOE Geopressured Geothermal Program is to improve methods for optimum energy extraction from geopressured reservoirs. Hybrid power systems which take advantage of the chemical and thermal energy content of geopressured fluids could improve conversion efficiency by 15 to 20% over the same amount of fuel and geothermal fluid processed separately. In a joint DOE/EPRI effort, equipment from the Direct Contact heat Exchange test facility at East Mesa is being modified for use in a unique geopressured hybrid power plant located at the Pleasant Bayou wellsite in Brazoria County, TX. Natural gas separated at the wellhead will fuel a gas turbine, and exhaust heat from the engine will be used with the geothermal brine to vaporize isobutane in a binary power cycle. The hybrid power system is designed for 10,000 bbl/day brine flow, with estimated power production of 980 kW (net). In addition to evaluating the enhanced performance resulting from the combined power generation cycles, operation of the hybrid unit will provide a demonstration of fuel flexibility in an individual plant. This approach would allow a resource developer to reduce costs and risks by optimizing production for various economic climates and would improve the mix in a utility's generating system. 5 refs., 2 figs.