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Sample records for british population fails

  1. Summary of the British Transplantation Society Guidelines for Management of the Failing Kidney Transplant.

    PubMed

    Andrews, Peter A

    2014-12-15

    The British Transplantation Society "Guideline for Transplantation Management of the Failing Kidney Transplant" was published in May 2014. This is the first national guideline in this field. In line with previous guidelines published by the British Transplantation Society, the guideline has used the GRADE system to rate the strength of evidence and recommendations.This article summarizes the Statements of Recommendation contained in the guideline, which provide a framework for the management of the failing kidney graft in the United Kingdom and may be of wide international interest. It is recommended that the full guideline document is consulted for details of the relevant references and evidence base. This may be accessed at: http://www.bts.org.uk/MBR/Clinical/Guidelines/Current/Member/Clinical/Current_Guidelines.aspx.

  2. Systemic Medication and Intraocular Pressure in a British Population

    PubMed Central

    Khawaja, Anthony P.; Chan, Michelle P.Y.; Broadway, David C.; Garway-Heath, David F.; Luben, Robert; Yip, Jennifer L.Y.; Hayat, Shabina; Wareham, Nicholas J.; Khaw, Kay-Tee; Foster, Paul J.

    2014-01-01

    Objective To determine the association between systemic medication use and intraocular pressure (IOP) in a population of older British men and women. Design Population-based, cross-sectional study. Participants We included 7093 participants from the European Prospective Investigation into Cancer–Norfolk Eye Study. Exclusion criteria were a history of glaucoma therapy (medical, laser, or surgical), IOP asymmetry between eyes of >5 mmHg, and missing data for any covariables. The mean age of participants was 68 years (range, 48–92) and 56% were women. Methods We measured IOP using the Ocular Response Analyzer. Three readings were taken per eye and the best signal value of the Goldmann-correlated IOP value considered. Participants were asked to bring all their medications and related documentation to the health examination, and these were recorded by the research nurse using an electronic case record form. The medication classes examined were angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, α-blockers, β-blockers, calcium channel blockers, diuretics, nitrates, statins, insulin, biguanides, sulfonylureas, aspirin, and other nonsteroidal anti-inflammatory drugs. We examined associations between medication use and IOP using multivariable linear regression models adjusted for age, sex, and body mass index. Models containing diabetic medication were further adjusted for glycosylated hemoglobin levels. Main Outcome Measures Mean IOP of the right and left eyes. Results Use of systemic β-blockers (−0.92 mmHg; 95% CI, −1.19, −0.65; P<0.001) and nitrates (−0.63 mmHg; 95% CI, −1.12, −0.14; P = 0.011) were independently associated with lower IOP. The observed associations between statin or aspirin use with IOP were no longer significant after adjustment for β-blocker use. Conclusions This is the first population-based study to demonstrate and quantify clinically significant differences in IOP among participants using systemic

  3. HIV testing, risk perception, and behaviour in the British population

    PubMed Central

    Clifton, Soazig; Nardone, Anthony; Field, Nigel; Mercer, Catherine H.; Tanton, Clare; Macdowall, Wendy; Johnson, Anne M.; Sonnenberg, Pam

    2016-01-01

    Objective: To examine the relationship between HIV risk behaviour, risk perception and testing in Britain. Design: A probability sample survey of the British population. Methods: We analyzed data on sexual behaviour, self-perceived HIV risk and HIV testing (excluding testing because of blood donation) from 13 751 sexually experienced men and women aged 16–74, interviewed between 2010 and 2012 using computer-assisted face-to-face and self-interviewing. Results: Altogether, 3.5% of men and 5.4% of women reported having an HIV test in the past year. Higher perceived risk of HIV was associated with sexual risk behaviours and with HIV testing. However, the majority of those rating themselves as ‘greatly’ or ‘quite a lot’ at risk of HIV (3.4% of men, 2.5% of women) had not tested in the past year. This was also found among the groups most affected by HIV: MSM and black Africans. Within these groups, the majority reporting sexual risk behaviours did not perceive themselves as at risk and had not tested for HIV. Overall, 29.6% of men and 39.9% of women who tested for HIV in the past year could be classified as low risk across a range of measures. Conclusion: Most people who perceive themselves as at risk of HIV have not recently tested, including among MSM and black Africans. Many people tested in Britain are at low risk, reflecting current policy that aims to normalize testing. Strategies to further improve uptake of testing are needed, particularly in those at greatest risk, to further reduce undiagnosed HIV infection at late diagnoses. PMID:26963528

  4. SunSmart? Skin Cancer Knowledge and Preventive Behaviour in a British Population Representative Sample

    ERIC Educational Resources Information Center

    Miles, A.; Waller, J.; Hiom, S.; Swanston, D.

    2005-01-01

    The incidence of skin cancer has risen rapidly in the UK over the last 20 years, prompting public health organizations to try and raise awareness of the dangers of sun exposure and the need to practice sun-safe behaviour. This study aimed to assess baseline levels of sun-safe knowledge and behaviour in a British population-representative sample,…

  5. The fine scale genetic structure of the British population

    PubMed Central

    Davison, Dan; Boumertit, Abdelhamid; Day, Tammy; Hutnik, Katarzyna; Royrvik, Ellen C; Cunliffe, Barry; Lawson, Daniel J; Falush, Daniel; Freeman, Colin; Pirinen, Matti; Myers, Simon; Robinson, Mark; Donnelly, Peter; Bodmer, Walter

    2015-01-01

    Summary Fine-scale genetic variation between human populations is interesting as a signature of historical demographic events and because of its potential for confounding disease studies. We use haplotype-based statistical methods to analyse genome-wide SNP data from a carefully chosen geographically diverse sample of 2,039 individuals from the United Kingdom (UK). This reveals a rich and detailed pattern of genetic differentiation with remarkable concordance between genetic clusters and geography. The regional genetic differentiation and differing patterns of shared ancestry with 6,209 individuals from across Europe carry clear signals of historical demographic events. We estimate the genetic contribution to SE England from Anglo-Saxon migrations to be under half, identify the regions not carrying genetic material from these migrations, suggest significant pre-Roman but post-Mesolithic movement into SE England from the Continent, and show that in non-Saxon parts of the UK there exist genetically differentiated subgroups rather than a general “Celtic” population. PMID:25788095

  6. Emerging Infectious Disease Leads to Rapid Population Declines of Common British Birds

    PubMed Central

    Toms, Mike P.; Peck, Kirsi M.; Kirkwood, James K.; Chantrey, Julian; Clatworthy, Innes R.; Evans, Andy D.; Hughes, Laura A.; Hutchinson, Oliver C.; John, Shinto K.; Pennycott, Tom W.; Perkins, Matthew W.; Rowley, Peter S.; Simpson, Vic R.; Tyler, Kevin M.; Cunningham, Andrew A.

    2010-01-01

    Emerging infectious diseases are increasingly cited as threats to wildlife, livestock and humans alike. They can threaten geographically isolated or critically endangered wildlife populations; however, relatively few studies have clearly demonstrated the extent to which emerging diseases can impact populations of common wildlife species. Here, we report the impact of an emerging protozoal disease on British populations of greenfinch Carduelis chloris and chaffinch Fringilla coelebs, two of the most common birds in Britain. Morphological and molecular analyses showed this to be due to Trichomonas gallinae. Trichomonosis emerged as a novel fatal disease of finches in Britain in 2005 and rapidly became epidemic within greenfinch, and to a lesser extent chaffinch, populations in 2006. By 2007, breeding populations of greenfinches and chaffinches in the geographic region of highest disease incidence had decreased by 35% and 21% respectively, representing mortality in excess of half a million birds. In contrast, declines were less pronounced or absent in these species in regions where the disease was found in intermediate or low incidence. Also, populations of dunnock Prunella modularis, which similarly feeds in gardens, but in which T. gallinae was rarely recorded, did not decline. This is the first trichomonosis epidemic reported in the scientific literature to negatively impact populations of free-ranging non-columbiform species, and such levels of mortality and decline due to an emerging infectious disease are unprecedented in British wild bird populations. This disease emergence event demonstrates the potential for a protozoan parasite to jump avian host taxonomic groups with dramatic effect over a short time period. PMID:20805869

  7. The prevalence of periodontal disease in a Romano-British population c. 200-400 AD

    PubMed Central

    Raitapuro-Murray, T.; Molleson, T. I.; Hughes, F. J.

    2014-01-01

    Objective The aim of this study was to investigate the prevalence of moderate to severe periodontitis in an ancient British cohort c. 200-400 AD. Design Observational study to assess periodontal and other oral disease parameters. Setting Natural History Museum, London. Subjects and methods 303 skulls from a Romano-British burial site in Poundbury, Dorset were examined for evidence of dental disease. Main outcome measures The primary outcome measure was presence of moderate to severe periodontitis. Secondary outcomes included: amount of horizontal bone loss; prevalence of ante-mortem tooth loss; and presence of other dental pathologies. Results The overall prevalence of moderate to severe periodontitis was just greater than 5%. The prevalence rate remained nearly constant between ages 20 to 60, after which it rose to around 10%. The number of affected teeth increased with age. Horizontal bone loss was generally minor. Caries was seen in around 50% of the cohort, and evidence of pulpal and apical pathology was seen in around 25%. Conclusions The prevalence of moderate to severe periodontitis was markedly decreased when compared to the prevalence in modern populations, underlining the potential importance of risk factors such as smoking and diabetes in determining susceptibility to progressive periodontitis in modern populations. PMID:25342357

  8. Replication of british rheumatoid arthritis susceptibility Loci in two unrelated chinese population groups.

    PubMed

    Li, Hua; Hu, Yonghe; Zhang, Tao; Liu, Yang; Wang, Yantang; Yang, Tai; Li, Minhui; Luo, Qiaoli; Cheng, Yu; Zou, Qiang

    2013-01-01

    Previous genome-wide association study by WTCCC identified many susceptibility loci of common autoimmune diseases in British, including rheumatoid arthritis (RA). Because of the genetic heterogeneity of RA, it is necessary to replicate these susceptibility loci in other populations. Here, three SNPs with strong RA association signal in the British were analyzed in Han Chinese, and two SNPs (rs6457617 and rs11761231) were genotyped in the test cohort firstly. The rs6457617 was significantly associated with RA in the test cohort. The individuals bearing the homozygous genotype CC had 0.39-fold risk than these bearing the wild-type genotype TT (P = 0.004, OR 0.39, [95% CI 0.21-0.74]). And the protective effect of allele C was confirmed in another validation cohort with 1514 samples (P genotye CC/TT = 5.9 ×  10(-10), OR 0.34, [95% CI 0.24-0.48]). The rs6457617 can be used as a tagSNP of HLA-DQA1∗03 which encoded MHC-II α chain. Since MHC restriction is important for primary T-cells in positive selection and negative selection stages, MHC protein polymorphisms may be implicated in shaping the T-cell repertoire, including the emergence of a T-cell clone involved in the inflammatory arthritis.

  9. Population genetics of the white-phased "Spirit" black bear of British Columbia.

    PubMed

    Hedrick, Philip W; Ritland, Kermit

    2012-02-01

    The Spirit (or Kermode) bear is a white-phased black bear found on the northwest coast of British Columbia, and is one of the most striking color polymorphisms found in mammals. A single nucleotide polymorphism at the melanocortin 1 receptor gene (mc1r) locus is the cause of this recessive w variant. Recently, evidence suggests that the white color provides a selective advantage during salmon hunting. Here we examine the effects of favorable selection, gene flow, genetic drift, and positive-assortative mating in an effort to understand the establishment and maintenance of this polymorphism and the observed heterozygote deficiency for mc1r but not for microsatellite loci. It appears that genetic drift was important in the establishment of the w allele and that the selective advantage was important to counteract immigration from populations without the w allele. Positive-assortative mating can result in a deficiency of heterozygotes but needs to be quite high to result in the large deficiency of heterozygotes observed, suggesting that other factors must also be contributing. Examination of population genetic factors, singly and jointly, provides insight into the establishment and maintenance of this unusual polymorphism.

  10. Birth weight from pregnancies dated by ultrasonography in a multicultural British population.

    PubMed

    Wilcox, M; Gardosi, J; Mongelli, M; Ray, C; Johnson, I

    1993-09-04

    A new set of standard curves of birth weight for singleton pregnancies with gestational age dated by ultrasonography was generated for the British population. The source of data was a computerized obstetric database of 41,718 pregnancies delivered between 168 and 300 days' gestation, taken from 3 large maternity units in East Midlands, the Nottingham University and City Hospitals, and Derby City Hospital. There were significant differences between the birthweights of 37,336 babies of mothers of English-European origin (3357 gm), 1008 babies of Afro-Caribbean origin (3173 gm), and 1547 babies of Indian subcontinent origin (3096 gm). There were also significant differences between ethnic groups for gestational length, parity, maternal height, weight, and smoking. These differences were greater than smoking was controlled. The effect of smoking was dose-related: at 40 weeks' gestation mean birthweights were 3580 gm for nonsmokers, 3416 gm for 1-9 cigarettes daily, 3374 gm for 10-19 cigarettes daily, and 3377 gm, for over 20 cigarettes daily. About 30% of the European and Afro-Caribbean women smoker, but almost none of the east Indians did. As had been seen elsewhere, ultrasound dating showed a lower gestational age than did menstrual dating (276 vs. 279 days), a discrepancy that is most likely to be clinically relevant in postdate gestations. While ultrasound dating is much more accurate, ethnic origin must be taken into account when assessing individuals.

  11. Occupations and lung cancer: a population-based case-control study in British Columbia.

    PubMed

    Yenugadhati, Nagarajkumar; Birkett, Nicholas J; Momoli, Franco; Krewski, Daniel

    2009-01-01

    An investigation based on a large population-based case-control study in British Columbia, Canada, was conducted to identify high-risk occupations for lung cancer by histological subtypes. Subjects were 14,755 male incident cancer cases for whom lifetime occupational histories and information on smoking and relevant covariates were collected. Occupational associations for 2998 lung cancer cases, including histological subtypes, were assessed by logistic regression using other cancer cases, excluding smoking-related cancers, as controls. An excess risk of lung cancer was found among workers in metal processing, bakers, and ship deck crew for all histological subtypes, and construction workers, chefs and cooks, and medical workers for specific histological subtypes. Occupational associations that are unique to histological subtypes of lung cancer were identified. Owing to a scarcity of literature in this area, future research needs to focus on confirming these histological associations, and identifying the risk from key exposures found within these occupations (e.g., medical radiation, electromagnetic fields, and cooking fumes).

  12. The use of denial in an ethnically diverse British cancer population: a cross-sectional study

    PubMed Central

    Roy, R; Symonds, R P; Kumar, D M; Ibrahim, K; Mitchell, A; Fallowfield, L

    2005-01-01

    A total of 82 Asian and 117 randomly selected white Caucasian patients at the Leicestershire Cancer Centre were assessed using measures of coping and adaption to cancer. On the Mental Adjustment to Cancer (MAC) scale, Asian patients were more fatalistic (P<0.0001) and had more significant hopeless/helpless scores (P=0.007). The two ethnic groups answered the three questions thought to assess denial differently. Caucasians were more likely not to dwell on their illness (73 vs 55.5%, P<0.0001) and agree with the statement ‘I have difficulty believing this is happening to me' (73 vs 60.5%, P<0.0001). However, Asian patients were more likely to agree with the statement ‘I don't really believe I have cancer' (48.2 vs 31.3%, P=0.019). Within both groups there was an association with denial and anxious preoccupation (P<0.001). On the Hospital Anxiety and Depression (HAD) scale, there was no difference in anxiety scores between either sexes or between the Asian and Caucasian groups. However, Asian patients were more depressed (P=0.001). Although denial was significantly related to the presence of both depression (P<0.0001) and anxiety (P=0.001) in the entire patient population, there were different predictors of denial in each subgroup. On multiple regression analysis depression was linked with denial in Caucasians, whereas Fighting Spirit (minus helplessness/hopelessness) was linked with denial in Asian patients. There are definite differences in coping styles in British cancer patients according to ethnicity. While significant numbers in both groups employ denial in some form, Caucasian patients appear to adapt to the psychological pressures of cancer more successfully than Asian patients at a particular point in time. Further work is required to elucidate longitudinal relationships between denial and adaption to cancer. PMID:15812548

  13. Population dynamics of the Cui-ui of Pyramid Lake, Nevada: a Potamodromous catostomid subject to failed reproduction

    USGS Publications Warehouse

    Scoppettone, Gayton G.; Rissler, Peter H.; Fabes, Mark C.; Shea, Sean P.

    2015-01-01

    Fishes of the Truckee River basin (California and Nevada) evolved in an aquatic system that has been episodically diminished by extended drought. For potamodromous species, such as the endangered Cui-ui endemic to Pyramid Lake, Nevada, prehistoric episodic severe drought presumably led to periods of failed reproduction due to restricted access to spawning habitat. The response of the Cui-ui population to more recent failed reproduction caused by anthropogenic activity was studied to learn how to manage this species through periods of spawning disruption. Adult Cui-ui survival averaged 91% and 89% for females and males, respectively, in drought years when spawning migrations were either precluded or few fish migrated because of no or low stream flow. In each of 2 years when stream access was precluded, the adult survival was nearly 100% suggesting that Cui-ui survival is extended in the absence of a spawning migration. Survival averaged 62% and 60% for females and males, respectively, in years of spawning migrations. Strong predominant year-classes developed in the year immediately following a period of failed reproduction, indicating the species’ capacity for population rebound. Year-class predominance persisted for 6–10 years and through years of low survival associated with migration years, and this predominance is probably due, in part, to a diverse age at maturity. Contemporary water diversions from the Truckee River provided the opportunity to study the response of the Cui-ui population to years of failed reproduction. A projected drier Truckee River basin associated with global climate change will test the Cui-ui’s adaptive capacity to endure periods of reproductive failure. This study is aimed at assisting Cui-ui managers in conserving the species in this highly regulated and changing system. The study also adds insight into the prehistoric population dynamics of a potamodromous species in the arid western United States subject to wide fluctuations in

  14. People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population.

    PubMed

    Winney, Bruce; Boumertit, Abdelhamid; Day, Tammy; Davison, Dan; Echeta, Chikodi; Evseeva, Irina; Hutnik, Katarzyna; Leslie, Stephen; Nicodemus, Kristin; Royrvik, Ellen C; Tonks, Susan; Yang, Xiaofeng; Cheshire, James; Longley, Paul; Mateos, Pablo; Groom, Alexandra; Relton, Caroline; Bishop, D Tim; Black, Kathryn; Northwood, Emma; Parkinson, Louise; Frayling, Timothy M; Steele, Anna; Sampson, Julian R; King, Turi; Dixon, Ron; Middleton, Derek; Jennings, Barbara; Bowden, Rory; Donnelly, Peter; Bodmer, Walter

    2012-02-01

    There is a great deal of interest in a fine-scale population structure in the UK, both as a signature of historical immigration events and because of the effect population structure may have on disease association studies. Although population structure appears to have a minor impact on the current generation of genome-wide association studies, it is likely to have a significant part in the next generation of studies designed to search for rare variants. A powerful way of detecting such structure is to control and document carefully the provenance of the samples involved. In this study, we describe the collection of a cohort of rural UK samples (The People of the British Isles), aimed at providing a well-characterised UK-control population that can be used as a resource by the research community, as well as providing a fine-scale genetic information on the British population. So far, some 4000 samples have been collected, the majority of which fit the criteria of coming from a rural area and having all four grandparents from approximately the same area. Analysis of the first 3865 samples that have been geocoded indicates that 75% have a mean distance between grandparental places of birth of 37.3 km, and that about 70% of grandparental places of birth can be classed as rural. Preliminary genotyping of 1057 samples demonstrates the value of these samples for investigating a fine-scale population structure within the UK, and shows how this can be enhanced by the use of surnames.

  15. People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population

    PubMed Central

    Winney, Bruce; Boumertit, Abdelhamid; Day, Tammy; Davison, Dan; Echeta, Chikodi; Evseeva, Irina; Hutnik, Katarzyna; Leslie, Stephen; Nicodemus, Kristin; Royrvik, Ellen C; Tonks, Susan; Yang, Xiaofeng; Cheshire, James; Longley, Paul; Mateos, Pablo; Groom, Alexandra; Relton, Caroline; Bishop, D Tim; Black, Kathryn; Northwood, Emma; Parkinson, Louise; Frayling, Timothy M; Steele, Anna; Sampson, Julian R; King, Turi; Dixon, Ron; Middleton, Derek; Jennings, Barbara; Bowden, Rory; Donnelly, Peter; Bodmer, Walter

    2012-01-01

    There is a great deal of interest in a fine-scale population structure in the UK, both as a signature of historical immigration events and because of the effect population structure may have on disease association studies. Although population structure appears to have a minor impact on the current generation of genome-wide association studies, it is likely to have a significant part in the next generation of studies designed to search for rare variants. A powerful way of detecting such structure is to control and document carefully the provenance of the samples involved. In this study, we describe the collection of a cohort of rural UK samples (The People of the British Isles), aimed at providing a well-characterised UK-control population that can be used as a resource by the research community, as well as providing a fine-scale genetic information on the British population. So far, some 4000 samples have been collected, the majority of which fit the criteria of coming from a rural area and having all four grandparents from approximately the same area. Analysis of the first 3865 samples that have been geocoded indicates that 75% have a mean distance between grandparental places of birth of 37.3 km, and that about 70% of grandparental places of birth can be classed as rural. Preliminary genotyping of 1057 samples demonstrates the value of these samples for investigating a fine-scale population structure within the UK, and shows how this can be enhanced by the use of surnames. PMID:21829225

  16. Temporal trends in ankyloglossia and frenotomy in British Columbia, Canada, 2004-2013: a population-based study

    PubMed Central

    Joseph, K.S.; Kinniburgh, Brooke; Metcalfe, Amy; Razaz, Neda; Sabr, Yasser; Lisonkova, Sarka

    2016-01-01

    Background: Routine surveillance of congenital anomalies has shown recent increases in ankyloglossia (tongue-tie) in British Columbia, Canada. We examined the temporal trends in ankyloglossia and its surgical treatment (frenotomy). Methods: We conducted a population-based cohort study involving all live births in British Columbia from Apr. 1, 2004, to Mar. 31, 2014, with data obtained from the province's Perinatal Data Registry. Spatiotemporal trends in ankyloglossia and frenotomy, and associations with maternal and infant characteristics, were quantified using logistic regression analysis. Results: There were 459 445 live births and 3022 cases of ankyloglossia between 2004 and 2013. The population incidence of ankyloglossia increased by 70% (rate ratio 1.70, 95% confidence interval [CI] 1.44-2.01), from 5.0 per 1000 live births in 2004 to 8.4 per 1000 in 2013. During the same period, the population rate of frenotomy increased by 89% (95% CI 52%-134%), from 2.8 per 1000 live births in 2004 to 5.3 per 1000 in 2013. The 2 regional health authorities with the lowest population rates of frenotomy (1.5 and 1.8 per 1000 live births) had the lowest rates of ankyloglossia and the lowest rates of frenotomy among cases with ankyloglossia, whereas the 2 regional health authorities with the highest population rates of frenotomy (5.2 and 5.3 per 1000 live births) had high rates of ankyloglossia and the highest rates of frenotomy among cases of ankyloglossia. Nulliparity, multiple birth, male infant sex, birth weight and year were independently associated with ankyloglossia. Interpretation: Large temporal increases and substantial spatial variations in ankyloglossia and frenotomy rates were observed that may indicate a diagnostic suspicion bias and increasing use of a potentially unnecessary surgical procedure among infants. PMID:27280112

  17. The association between population-based treatment guidelines and adjuvant therapy for node-negative breast cancer. British Columbia/Ontario Working Group.

    PubMed Central

    Sawka, C.; Olivotto, I.; Coldman, A.; Goel, V.; Holowaty, E.; Hislop, T. G.

    1997-01-01

    This study evaluated the impact of province-wide treatment guidelines on consistency of adjuvant therapy for node-negative breast cancer. A retrospective population-based cohort study was conducted in the Canadian provinces of British Columbia, which has province-wide guidelines, and Ontario, which does not. All eligible 1991 incident cases of node-negative breast cancer in British Columbia (n = 942) and a similar number of randomly selected 1991 incident cases in Ontario (n = 938) were reviewed. Consistency of adjuvant therapy received was evaluated by stratifying cases into discrete diagnostic groups using several grouping systems, and by then comparing the distribution of treatments received within each diagnostic group in the two provinces. Recursive partitioning was also performed. We observed that patterns of pathology reporting were consistent with awareness of the factors used in the British Columbia guidelines to define indications for adjuvant therapy. Consistency of care was greater in British Columbia than in Ontario by all diagnostic grouping systems and by recursive partitioning (P < 0.001), and the observed patterns in British Columbia corresponded to the British Columbia guidelines. We conclude that population-based treatment guidelines can play a role in promoting consistent patterns of adjuvant therapy for women with node-negative breast cancer. PMID:9166950

  18. Immunoglobulin (GM and KM) allotypes and relation to population history in native peoples of British Columbia: Haida and Bella Coola.

    PubMed

    Field, L L; Gofton, J P; Kinsella, T D

    1988-06-01

    Differences in the frequencies of GM haplotypes among native peoples of the Americas support the hypothesis that there were three distinct waves of migration from northeast Asia into the Americas: Paleo-Indian, Na-Dene, and Inuit (Eskimo)-Aleut (Salzano and Steinberg: Am. J. Hum. Genet. 17:273-279, 1965; Sukernik and Osipova: Hum. Genet. 61:148-153, 1982; Williams et al.:Am. J. Phys. Anthropol. 66:1-19, 1985; Szathmary: In R Kirk and E Szathmary (eds): Out of Asia: Peopling of the Americas and the Pacific. Canberra: The Journal of Pacific History, Canberra Australian National University, pp. 79-104, 1985). We studied GM allotypes in two linguistically unique populations of Canadian west coast native peoples, the Haida and the Bella Coola, and compared them to GM frequencies in populations that are supposed descendants of the three migrations, in order to investigate the possible genetic relationships of these British Columbia (BC) groups to other native populations. We also estimated the amount of European admixture from the frequency of the Caucasian haplotype, Gm3;5. Results showed that the frequencies in both BC populations of the three common native haplotypes (Gm1,17;21, Gm1,2,17;21, and Gm1,17;15,16), were intermediate between the frequencies in supposed descendants of Paleo-Indian and Na-Dene. These genetic findings are consistent with the controversial hypothesis of archeologist C. Borden (Science 203:963-971, 1979) that, following deglaciation about 13,000 years ago, British Columbia was repopulated by peoples from the north (?Na-Dene) and by culturally distinct peoples from the south (?Paleo-Indian). Caucasian admixture estimates suggested that the Haida and Bella Coola have also experienced moderate amounts (12-20%) of genetic input from European-originating peoples.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. Predicting tuberculosis risk in the foreign-born population of British Columbia, Canada: study protocol for a retrospective population-based cohort study

    PubMed Central

    Ronald, Lisa A; Campbell, Jonathon R; Balshaw, Robert F; Roth, David Z; Romanowski, Kamila; Marra, Fawziah; Cook, Victoria J; Johnston, James C

    2016-01-01

    Introduction Improved understanding of risk factors for developing active tuberculosis (TB) will better inform decisions about diagnostic testing and treatment for latent TB infection (LTBI) in migrant populations in low-incidence regions. We aim to examine TB risk factors among the foreign-born population in British Columbia (BC), Canada, and to create and validate a clinically relevant multivariate risk score to predict active TB. Methods and analysis This retrospective population-based cohort study will include all foreign-born individuals who acquired permanent resident status in Canada between 1 January 1985 and 31 December 2013 and acquired healthcare coverage in BC at any point during this period. Multiple administrative databases and disease registries will be linked, including a National Immigration Database, BC Provincial Health Insurance Registration, physician billings, hospitalisations, drugs dispensed from community pharmacies, vital statistics, HIV testing and notifications, cancer, chronic kidney disease and dialysis treatment, and all TB and LTBI testing and treatment data in BC. Extended proportional hazards regression will be used to estimate risk factors for TB and to create a prognostic TB risk score. Ethics and dissemination Ethical approval for this study has been obtained from the University of British Columbia Clinical Ethics Review Board. Once completed, study findings will be presented at conferences and published in peer-reviewed journals. An online TB risk score calculator will also be created. PMID:27888179

  20. The Extent and Distribution of Gambling-Related Harms and the Prevention Paradox in a British Population Survey

    PubMed Central

    Canale, Natale; Vieno, Alessio; Griffiths, Mark D.

    2016-01-01

    Objectives To examine whether the “prevention paradox” applies to British individuals in relation to gambling-related harm. Methods Data were derived from 7,756 individuals participating in the British Gambling Prevalence Survey 2010, a comprehensive interview-based survey conducted in Great Britain between November 2009 and May 2010. Gambling-related harm was assessed using an adapted version of the DSM-IV Pathological Gambling criteria. The previous year’s prevalence of problem gamblers was examined using the Problem Gambling Severity Index. Gambling involvement was measured by gambling frequency and gambling participation (gambling volume as expressed by time and money spent gambling). Results The prevalence rates for past-year gambling harms were dependence harm (16.4%), social harm (2.2%), and chasing losses (7.9%). Gambling-related harms were distributed across low- to moderate-risk gamblers (and not limited to just problem gamblers) and were reported by the majority of gamblers who were non-high time and spend regular gamblers than high time and spend regular gamblers. Conclusions The prevention paradox is a promising way of examining gambling-related harm. This suggests that prevention of gambling might need to consider the population approach to minimizing gambling harm. PMID:27156382

  1. Simulation model of Cryptomonas ovata population dynamics in southern Kootenay Lake, British Columbia

    USGS Publications Warehouse

    Cloern, James E.

    1978-01-01

    The model simulates well the timing and magnitude of all observed population changes and, more importantly, it gives insight into the important mechanisms which regulate population density of C. ovata in this natural system.

  2. Lizards fail to plastically adjust nesting behavior or thermal tolerance as needed to buffer populations from climate warming.

    PubMed

    Telemeco, Rory S; Fletcher, Brooke; Levy, Ofir; Riley, Angela; Rodriguez-Sanchez, Yesenia; Smith, Colton; Teague, Collin; Waters, Amanda; Angilletta, Michael J; Buckley, Lauren B

    2017-03-01

    Although observations suggest the potential for phenotypic plasticity to allow adaptive responses to climate change, few experiments have assessed that potential. Modeling suggests that Sceloporus tristichus lizards will need increased nest depth, shade cover, or embryonic thermal tolerance to avoid reproductive failure resulting from climate change. To test for such plasticity, we experimentally examined how maternal temperatures affect nesting behavior and embryonic thermal sensitivity. The temperature regime that females experienced while gravid did not affect nesting behavior, but warmer temperatures at the time of nesting reduced nest depth. Additionally, embryos from heat-stressed mothers displayed increased sensitivity to high-temperature exposure. Simulations suggest that critically low temperatures, rather than high temperatures, historically limit development of our study population. Thus, the plasticity needed to buffer this population has not been under selection. Plasticity will likely fail to compensate for ongoing climate change when such change results in novel stressors.

  3. A first integrative study of the identity and origins of the British Dwarf Pill Millipede populations, Trachysphaera cf. lobata (Diplopoda, Glomerida, Glomeridae)

    PubMed Central

    Wilbrandt, Jeanne; Lee, Paul; Read, Helen

    2015-01-01

    Abstract Three populations of the pill millipede genus Trachysphaera Heller 1858 are present in Great Britain, one on the Isle of Wight, one in South Wales and one in mid-Wales. To identify and characterize the British Trachysphaera populations, the intraspecific and interspecific variation of the populations in South Wales and on the Isle of Wight were studied and evaluated in a first integrative study of members of Trachysphaera, utilizing barcoding and SEM. DNA was extracted from 28 British Trachysphaera and 10 French T. lobata (Ribaut 1954) specimens, one each of French T. cf. drescoi (Conde and Demange 1961) and T. pyrenaica (Ribaut 1908), and one of Spanish T. cf. rousseti (Demange 1959); the barcoding fragment of the COI gene was amplified and their genetic intra- and interpopulation distances compared with one another using two Italian T. spp. and one Croatian T. schmidti Heller 1858 specimens as near outgroups. To compare the genetic distances with the morphological characters, 15 characters of a total of 13 British Trachysphaera, together with two specimens of T. pyrenaica, two T. cf. drescoi and one of T. cf. rousseti were imaged, using the same individuals utilized for DNA extraction. Albeit both British populations are genetically distant, they are closely related (1.9–2.5% p-distance) to French T. lobata, corroborating results of earlier studies. Between different Trachysphaera species, genetic distance was high (16.7–18.8%). The morphological study showed the non-reliability of key taxonomic characters in Trachysphaera, with genetically identical individuals exhibiting morphological variation, especially on the telopods. The only observed morphological characters constant within and different between species were the number of rows of sclerotized bacilli on the tergites, as well as the shape of the male and female anal shield. Both, barcoding and the morphological study identify the British Trachysphaera populations as T. lobata. PMID:26175612

  4. Disparities in Paediatric Injury Mortality between Aboriginal and Non-Aboriginal Populations in British Columbia, 2001–2009

    PubMed Central

    Amram, Ofer; Walker, Blake Byron; Schuurman, Nadine; Pike, Ian; Yanchar, Natalie

    2016-01-01

    Injury is the leading cause of death among children and youth in Canada. Significant disparities in injury mortality rates have been observed between Aboriginal and non-Aboriginal populations, but little is known about the age-, sex-, and mechanism-specific patterns of injury causing death. This study examines paediatric mortality in British Columbia from 2001 to 2009 using comprehensive vital statistics registry data. We highlight important disparities in Aboriginal and non-Aboriginal mortality rates, and use the Preventable Years of Life Lost (PrYLL) metric to identify differences between age groups and the mechanisms of injury causing death. A significantly greater age-adjusted mortality rate was observed among Aboriginal children (OR = 2.08, 95% CI: 1.41, 3.06), and significantly higher rates of death due to assault, suffocation, and fire were detected for specific age groups. Mapped results highlight regional disparities in PrYLL across the province, which may reflect higher Aboriginal populations in rural and remote areas. Crucially, these disparities underscore the need for community-specific injury prevention policies, particularly in regions with high PrYLL. PMID:27399748

  5. Sex differences in cadmium accumulation in a laboratory population of a wild British insectivore, Sorex araneux

    SciTech Connect

    Dodds-Smith, M.E.; Johnson, M.S.; Thompson, D.J.

    1986-01-01

    A series of feeding trials using laboratory reared common shrews Sorex araneus were undertaken to examine the accumulation of Cd in a known trace metal accumulator. A significant sex difference in Cd accumulation in the liver and kidney was identified. The results are discussed in relation to data on traditional laboratory animals and field studies on wild populations of small mammals. 9 references, 3 figures.

  6. Occupational, domestic and environmental mesothelioma risks in the British population: a case–control study

    PubMed Central

    Rake, C; Gilham, C; Hatch, J; Darnton, A; Hodgson, J; Peto, J

    2009-01-01

    We obtained lifetime occupational and residential histories by telephone interview with 622 mesothelioma patients (512 men, 110 women) and 1420 population controls. Odds ratios (ORs) were converted to lifetime risk (LR) estimates for Britons born in the 1940s. Male ORs (95% confidence interval (CI)) relative to low-risk occupations for >10 years of exposure before the age of 30 years were 50.0 (25.8–96.8) for carpenters (LR 1 in 17), 17.1 (10.3–28.3) for plumbers, electricians and painters, 7.0 (3.2–15.2) for other construction workers, 15.3 (9.0–26.2) for other recognised high-risk occupations and 5.2 (3.1–8.5) in other industries where asbestos may be encountered. The LR was similar in apparently unexposed men and women (∼1 in 1000), and this was approximately doubled in exposed workers' relatives (OR 2.0, 95% CI 1.3–3.2). No other environmental hazards were identified. In all, 14% of male and 62% of female cases were not attributable to occupational or domestic asbestos exposure. Approximately half of the male cases were construction workers, and only four had worked for more than 5 years in asbestos product manufacture. PMID:19259084

  7. Elective single-embryo transfer: persuasive communication strategies can affect choice in a young British population.

    PubMed

    van den Akker, O B A; Purewal, S

    2011-12-01

    This study tested the effectiveness of the framing effect and fear appeals to inform young people about the risks of multiple births and the option of selecting elective single-embryo transfer (eSET). A non-patient student sample (age (mean±SD) 23±5.5 years; n=321) were randomly allocated to one of seven groups: (1) framing effect: (1a) gain and (1b) loss frame; (2) fear appeal: (2a) high, (2b) medium and (2c) low fear; or (3) a control group: (3a) education and (3b) non-education. The primary outcome measure was the Attitudes towards Single Embryo Transfer questionnaire, before exposure to the messages (time 1) and immediately afterwards (time 2). Results revealed participants in the high fear, medium fear and gain condition demonstrated the most positive and significant differences (P<0.001 to P<0.05) in their knowledge, hypothetical intentions and modest changes in attitudes towards eSET than the low fear, loss frame and education and non-education messages. The results demonstrate that the use of complex persuasive communication techniques on a student population to promote immediate and hypothetical eSET preferences is more successful at promoting eSET than merely reporting educational content. Future research should investigate its application in a clinical population. A multiple pregnancy is a health risk to both infant and mother following IVF treatment. The aims of this study were to test the effectiveness of two persuasive communication techniques (the framing effect and fear appeals) to inform young people about the risks of multiple births and the hypothetical option of selecting elective single-embryo transfer (eSET) (i.e., only one embryo is transferred to the uterus using IVF treatment). A total of 321 non-patient student sample (mean age 23) were randomly allocated to read a message from one of seven groups: (1) framing effect: (1a) gain and (1b) loss frame; (2) fear appeal: (2a) high, (2b) medium and (2c) low fear; or (3) a control group

  8. British Nuclear Policymaking,

    DTIC Science & Technology

    1984-01-01

    devoted to capital spending.’ This has all Laken place although Britain’s economy has been seriously troubled by inflation, low productivity, and...American support was required to counterbalance Soviet influence in Western.Europe, Iran, Turkey, and Greece. Britain’s exhausted economy loomed as an...for a British deterrent. The simple truth is that when the Empire crumbled and the economy failed to recover, nuclear weapons became-and continue to

  9. Differences in heat-related mortality across four ecological regions with diverse urban, rural, and remote populations in British Columbia, Canada.

    PubMed

    Henderson, Sarah B; Wan, Victoria; Kosatsky, Tom

    2013-09-01

    Temperature-mortality analyses are challenging in rural and remote communities with small populations, but this information is needed for climate change and emergency planning. The geographic health areas of British Columbia, Canada were aggregated into four ecoregions delineated by microclimatic conditions. Time series models were used to estimate the effect of maximum apparent temperature on daily non-traumatic mortality. The population of the coldest ecoregion was most sensitive to hot weather, while the population of the hottest ecoregion was least sensitive. The effects were consistently strongest in decedents aged less than 75 years. A province-wide total of 815 deaths was attributed to hot weather over the 25-year study period, with 735 deaths in the most populous ecoregion. The framework described could be adapted to other climatically variable regions with urban, rural, and remote populations.

  10. Mealtime Energy Intake and Feeding Behaviour in Children Who Fail to Thrive: A Population-Based Case-Control Study

    ERIC Educational Resources Information Center

    Parkinson, Kathryn N.; Wright, Charlotte M.; Drewett, Robert F.

    2004-01-01

    Background: The essential link between energy needs and energy intake is feeding behaviour, yet few studies have directly observed feeding behaviour in children who have failed to thrive. A cohort of 961 term infants was screened to identify children with first year weight gain below the 5th centile in order to examine their feeding behaviour and…

  11. Prevalence of lower gastrointestinal symptoms and associated consultation behaviour in a British elderly population determined by face-to-face interview.

    PubMed Central

    Chaplin, A; Curless, R; Thomson, R; Barton, R

    2000-01-01

    BACKGROUND: The incidence of organic lower gastrointestinal disease increases with age. However, the prevalence of lower gastrointestinal symptoms in a British elderly population is unclear, with previous epidemiological studies focusing on younger populations. Furthermore, there is little information about consultation behaviour associated with lower gastrointestinal symptoms. AIM: To determine the prevalence of lower gastrointestinal symptoms reported by randomly selected, elderly community subjects. METHODS: An age- and sex-stratified random sample of patients aged 65 years and over was drawn from a general practice register (n = 842). Those who had not refused to participate in an initial postal survey were invited to participate in a semi-structured physician interview at their own home to assess lower gastrointestinal symptomatology (n = 745). Non-participation bias and service use of all subjects were assessed from practice records. RESULTS: Five hundred and ninety-six (71%) patients were interviewed. Fifty-seven per cent of all participants had at least one lower gastrointestinal symptom. Individual symptoms and symptom complexes were common, affecting up to 32% of subjects. Only 24% of subjects with lower gastrointestinal symptoms consulted their general practitioner (GP) with such symptoms in the previous year. As few as 31% of subjects with new onset of the significant symptoms of rectal bleeding, abdominal pain, and a change in bowel habit consulted their GP. CONCLUSION: Lower gastrointestinal symptoms are common in a British elderly population and an important reason for GP consultation. PMID:11127169

  12. British Columbia

    ERIC Educational Resources Information Center

    Walton, Gerald

    2006-01-01

    The province of British Columbia has a dubious history where support for lesbian, gay, bisexual, and transgendered (LGBT) issues in education is concerned. Most notable is the Surrey School Board's decision in 1997 to ban three picture books for children that depict families with two moms or two dads. The North Vancouver School Board has also…

  13. Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population.

    PubMed

    Way, Michael; McQuillin, Andrew; Saini, Jit; Ruparelia, Kush; Lydall, Gregory J; Guerrini, Irene; Ball, David; Smith, Iain; Quadri, Giorgia; Thomson, Allan D; Kasiakogia-Worlley, Katherine; Cherian, Raquin; Gunwardena, Priyanthi; Rao, Harish; Kottalgi, Girija; Patel, Shamir; Hillman, Audrey; Douglas, Ewen; Qureshi, Sherhzad Y; Reynolds, Gerry; Jauhar, Sameer; O'Kane, Aideen; Dedman, Alex; Sharp, Sally; Kandaswamy, Radhika; Dar, Karim; Curtis, David; Morgan, Marsha Y; Gurling, Hugh M D

    2015-05-01

    Certain single nucleotide polymorphisms (SNPs) in genes encoding alcohol dehydrogenase (ADH) enzymes confer a significant protective effect against alcohol dependence syndrome (ADS) in East Asian populations. Recently, attention has focused on the role of these SNPs in determining ADS risk in European populations. To further elucidate these associations, SNPs of interest in ADH1B, ADH1C and the ADH1B/1C intergenic region were genotyped in a British and Irish population (ADS cases n = 1076: controls n = 1027) to assess their relative contribution to ADS risk. A highly significant, protective association was observed between the minor allele of rs1229984 in ADH1B and ADS risk [allelic P = 8.4 × 10(-6) , odds ratio (OR) = 0.26, 95 percent confidence interval, 0.14, 0.49]. Significant associations were also observed between ADS risk and the ADH1B/1C intergenic variant, rs1789891 [allelic P = 7.2 × 10(-5) , OR = 1.4 (1.2, 1.6)] and three non-synonymous SNPs rs698, rs1693482 and rs283413 in ADH1C. However, these associations were not completely independent; thus, while the ADH1B rs1229984 minor allele association was independent of those of the intergenic variant rs1789891 and the three ADH1C variants, the three ADH1C variants were not individually independent. In conclusion, the rare ADH1B rs1229984 mutation provides significant protection against ADS in this British and Irish population; other variants in the ADH gene cluster also alter ADS risk, although the strong linkage disequilibrium between SNPs at this location precluded clear identification of the variant(s) driving the associations.

  14. Heterogeneity in Genetic Diversity among Non-Coding Loci Fails to Fit Neutral Coalescent Models of Population History

    PubMed Central

    Peters, Jeffrey L.; Roberts, Trina E.; Winker, Kevin; McCracken, Kevin G.

    2012-01-01

    Inferring aspects of the population histories of species using coalescent analyses of non-coding nuclear DNA has grown in popularity. These inferences, such as divergence, gene flow, and changes in population size, assume that genetic data reflect simple population histories and neutral evolutionary processes. However, violating model assumptions can result in a poor fit between empirical data and the models. We sampled 22 nuclear intron sequences from at least 19 different chromosomes (a genomic transect) to test for deviations from selective neutrality in the gadwall (Anas strepera), a Holarctic duck. Nucleotide diversity among these loci varied by nearly two orders of magnitude (from 0.0004 to 0.029), and this heterogeneity could not be explained by differences in substitution rates alone. Using two different coalescent methods to infer models of population history and then simulating neutral genetic diversity under these models, we found that the observed among-locus heterogeneity in nucleotide diversity was significantly higher than expected for these simple models. Defining more complex models of population history demonstrated that a pre-divergence bottleneck was also unlikely to explain this heterogeneity. However, both selection and interspecific hybridization could account for the heterogeneity observed among loci. Regardless of the cause of the deviation, our results illustrate that violating key assumptions of coalescent models can mislead inferences of population history. PMID:22384117

  15. Biology and Conservation of the Common Murre in California, Oregon, Washington, and British Columbia: Vol. 1, Natural History and Population Trends

    USGS Publications Warehouse

    Manuwal, David Allen; Carter, Harry R.; Zimmerman, Tara S.; Orthmeyer, Dennis L.

    2001-01-01

    EXECUTIVE SUMMARY Over the past 30 years, the common murre (Uria aalge californica) has been recognized as a prominent indicator of marine conservation issues in California, Oregon, Washington, and British Columbia, especially regarding oil pollution, certain fisheries, and human disturbance. To assist the effective management of the common murre and the marine environments in which they live, this summary of available information on the biology and regional status of the common murre has been sponsored by the U.S. Fish and Wildlife Service (Division of Migratory Bird Management). In Volume 1 (Chapter 1), the natural history of the common murre is summarized, drawing heavily on breeding studies from the South Farallon Islands, California, plus a host of detailed breeding studies from the North Atlantic Ocean. Population trends of the common murre are summarized in Volume 1 (Chapter 2), focusing on changes in whole-colony counts determined from aerial photographs between the late 1970s and 1995 in California, Oregon and Washington. Historical data and human impacts to murre colonies since the early nineteenth century are also summarized. Volume 2 will summarize population threats, conservation, and management. Information presented in Volume 1 has been obtained and recorded by a large number of researchers and natural historians over two centuries. From the 1960s to 1995, most work in California, Oregon, and Washington was sponsored by the U.S. Fish and Wildlife Service, Minerals Management Service, and California Department of Fish and Game. Important breeding biology studies were conducted at the South Farallon Islands (Farallon National Wildlife Refuge) by the Point Reyes Bird Observatory, in coordination with the U.S. Fish and Wildlife Service (San Francisco Bay National Wildlife Refuge). Colony surveys in California were conducted mainly by the U.S. Fish and Wildlife Service (San Francisco Bay National Wildlife Refuge), U.S. Geological Survey (Western

  16. Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population.

    PubMed

    Leng, Yue; Wainwright, Nick W J; Cappuccio, Francesco P; Surtees, Paul G; Hayat, Shabina; Luben, Robert; Brayne, Carol; Khaw, Kay-Tee

    2014-05-01

    Epidemiologic studies have reported conflicting results on the relationship between daytime napping and mortality risk, and there are few data on the potential association in the British population. We investigated the associations between daytime napping and all-cause or cause-specific mortality in the European Prospective Investigation Into Cancer-Norfolk study, a British population-based cohort study. Among the 16,374 men and women who answered questions on napping habits between 1998 and 2000, a total of 3,251 died during the 13-year follow-up. Daytime napping was associated with an increased risk of all-cause mortality (for napping less than 1 hour per day on average, hazard ratio = 1.14, 95% confidence interval: 1.02, 1.27; for napping 1 hour or longer per day on average, hazard ratio = 1.32, 95% confidence interval: 1.04, 1.68), independent of age, sex, social class, educational level, marital status, employment status, body mass index, physical activity level, smoking status, alcohol intake, depression, self-reported general health, use of hypnotic drugs or other medications, time spent in bed at night, and presence of preexisting health conditions. This association was more pronounced for death from respiratory diseases (for napping less than 1 hour, hazard ratio = 1.40, 95% confidence interval: 0.95, 2.05; for napping 1 hour or more, hazard ratio = 2.56, 95% confidence interval: 1.34, 4.86) and in individuals 65 years of age or younger. Excessive daytime napping might be a useful marker of underlying health risk, particularly of respiratory problems, especially among those 65 years of age or younger. Further research is required to clarify the nature of the observed association.

  17. Second primary neoplasms in survivors of Wilms' tumour--a population-based cohort study from the British Childhood Cancer Survivor Study.

    PubMed

    Taylor, Aliki J; Winter, David L; Pritchard-Jones, Kathy; Stiller, Charles A; Frobisher, Clare; Lancashire, Emma R; Reulen, Raoul C; Hawkins, Mike M

    2008-05-01

    A British population-based cohort study was carried out to determine the risk of second primary neoplasms in survivors of Wilms' tumour. The cohort was obtained from the British Childhood Cancer Survivor Study, a population-based cohort study of treatment toxicities in 18,044 individuals diagnosed with childhood cancer, at an age of less than 15 years, between 1940 and 1991 in Britain. There were 1,441 Wilms' tumour survivors in the cohort: 732 males (50.8%) and 709 females (49.2%). Total follow-up from 5-year survival was 27,841 person years, mean follow-up of 19.3 years per survivor. There were 81 second primary neoplasms, including 52 solid neoplasms, 3 acute myeloid leukaemias and 26 basal cell carcinomas. Thirty-five of the 39 solid neoplasms that developed in the thoracic, abdominal or pelvic region occurred within irradiated tissue. The standardised incidence ratio for all solid second primary neoplasms was 6.7 (95% CI: 5.0-8.8). Cumulative incidence for all solid second primary neoplasms by ages 30, 40 and 50 years was 2.3% (1.4-3.5%), 6.8% (4.6-9.5%) and 12.2% (7.3-18.4%). The overall risk of second primary neoplasms in survivors of Wilms' tumour treated between 1940 and 1991 was substantial, and solid second tumours tended to develop in the irradiated tissue. Continued follow-up of these survivors is important to monitor such late effects of treatment. It is also important to evaluate the risk of second primary neoplasms following more recent lower radiation dose treatment practices.

  18. Diversity, genetic structure and evidence of outcrossing in British populations of the rock fern Adiantum capillus-veneris using microsatellites.

    PubMed

    Pryor, K V; Young, J E; Rumsey, F J; Edwards, K J; Bruford, M W; Rogers, H J

    2001-08-01

    Microsatellites were isolated and a marker system was developed in the fern Adiantum capillus-veneris. Polymorphic markers were then used to study the genetic diversity and structure of populations within the UK and Ireland where this species grows at the northern edge of its range, requiring a specific rock habitat and limited to a few scattered populations. Three dinucleotide loci detected a high level of diversity (23 alleles and 28 multilocus genotypes) across the UK and Ireland, with nearly all variation partitioned among rather than within populations. Of 17 populations represented by multiple samples, all except four were monomorphic. Heterozygosity was detected in three populations, all within Glamorgan, Wales (UK), showing evidence of outcrossing. We make inferences on the factors determining the observed levels and patterns of genetic variation and the possible evolutionary history of the populations.

  19. Evolution of population genetic structure of the British roe deer by natural and anthropogenic processes (Capreolus capreolus).

    PubMed

    Baker, Karis H; Rus Hoelzel, A

    2012-01-01

    Human influence typically impacts on natural populations of conservation interest. These interactions are varied and sometimes complex, and may be negative and unintended or associated with conservation and management strategy. Understanding the details of how these interactions influence and are influenced by natural evolutionary processes is essential to the development of effective conservation strategies. In this study, we investigate a species in Britain that has experienced both negative impact through overhunting in historical times and management efforts through culls and translocations. At the same time, there are regional populations that have been less affected by human influence. We use mtDNA and nuclear microsatellite DNA markers to investigate patterns of connectivity and diversity and find multiple insular populations in Britain that probably evolved within the Holocene (when the habitat was free of ice). We identify three concurrent processes. First, surviving indigenous populations show highly provincial patterns of philopatry, maintaining and generating population structure on a small geographic scale. Second, founder populations into habitat extirpated of native populations have expanded, but remained largely insular. Third, introductions into established populations generate some admixture. We discuss the implications for the evolution of diversity of the integration of natural processes with anthropogenic influences on population size and distribution.

  20. Facilitators of and barriers to accessing clinical prevention services for the South Asian population in Surrey, British Columbia: a qualitative study

    PubMed Central

    Majid, Sanaa; Douglas, Rachel; Lee, Victoria; Stacy, Elizabeth; Garg, Arun K.; Ho, Kendall

    2016-01-01

    Background: British Columbia falls short in uptake of recommended clinical prevention services, with even lower rates among immigrant populations. This study explored facilitators of and barriers to uptake of clinical prevention services among people from South Asia, who represent 31% of the population in Surrey, British Columbia. Methods: We used a qualitative descriptive approach and employed vignettes in a focus group setting to elicit perspectives of South Asian people on accessing clinical prevention services. Participants aged 40 years or more were recruited between October 2014 and February 2015 from health care and community settings such as older-adult housing, day programs and health education events. Letters of introduction to the study were provided in English or Punjabi or both to all potential participants. We conducted qualitative content analysis of the results. Results: Sixty-two South Asian adults (36 women and 26 men) aged 40-87 years participated in 1 of 8 focus groups in health care or community settings. Facilitators of and barriers to accessing clinical prevention services were noted at the patient, primary care provider and health care system levels. Facilitators at the patient level included taking ownership over one's health, health literacy and respecting the provider's advice; barriers included fear of the diagnosis, death and/or procedures, perceived low risk of disease or utility of the intervention, and side effects of procedures. Provider factors centred on a trust-based patient-provider relationship, strong communication and adequate time during visits. Health care system factors included such facilitators as processes to routinely offer prevention services as part of other health care or social services, systems that encourage prevention-oriented family practice and services at low or no cost to the patient. Interpretation: Our findings validate previously identified facilitators of and barriers to accessing preventive care for

  1. Worker compensation injuries among the Aboriginal population of British Columbia, Canada: incidence, annual trends, and ecological analysis of risk markers, 1987–2010

    PubMed Central

    2014-01-01

    Background Aboriginal people in British Columbia (BC) have higher injury incidence than the general population, but information is scarce regarding variability among injury categories, time periods, and geographic, demographic and socio-economic groups. Our project helps fill these gaps. This report focuses on workplace injuries. Methods We used BC’s universal health care insurance plan as a population registry, linked to worker compensation and vital statistics databases. We identified Aboriginal people by insurance premium group and birth and death record notations. We identified residents of specific Aboriginal communities by postal code. We calculated crude incidence rate and Standardized Relative Risk (SRR) of worker compensation injury, adjusted for age, gender and Health Service Delivery Area (HSDA), relative to the total population of BC. We assessed annual trend by regressing SRR as a linear function of year. We tested hypothesized associations of geographic, socio-economic, and employment-related characteristics of Aboriginal communities with community SRR of injury by multivariable linear regression. Results During the period 1987–2010, the crude rate of worker compensation injury in BC was 146.6 per 10,000 person-years (95% confidence interval: 146.4 to 146.9 per 10,000). The Aboriginal rate was 115.6 per 10,000 (95% CI: 114.4 to 116.8 per 10,000) and SRR was 0.88 (95% CI: 0.87 to 0.89). Among those living on reserves SRR was 0.79 (95% CI: 0.78 to 0.80). HSDA SRRs were highly variable, within both total and Aboriginal populations. Aboriginal males under 35 and females under 40 years of age had lower SRRs, but older Aboriginal females had higher SRRs. SRRs are declining, but more slowly for the Aboriginal population. The Aboriginal population was initially at lower risk than the total population, but parity was reached in 2006. These community characteristics independently predicted injury risk: crowded housing, proportion of population who

  2. Trends and Determinants of Prescription Drug Use during Pregnancy and Postpartum in British Columbia, 2002–2011: A Population-Based Cohort Study

    PubMed Central

    Smolina, Kate; Hanley, Gillian E.; Mintzes, Barbara; Oberlander, Tim F.; Morgan, Steve

    2015-01-01

    Purpose To describe trends, patterns, and determinants of prescription drug use during pregnancy and postpartum. Methods This is a retrospective, population-based study of all women who gave birth between January 2002 and 31 December 2011 in British Columbia, Canada. Study population consisted of 225,973 women who had 322,219 pregnancies. We examined administrative datasets containing person-specific information on filled prescriptions, hospitalizations, and medical services. Main outcome measures were filled prescriptions during pregnancy and postpartum. We used logistic regressions to examine associations between prescription drug use and maternal characteristics. Results Approximately two thirds of women filled a prescription during pregnancy, increasing from 60% in 2002 to 66% in 2011. The proportion of pregnant women using medicines in all three trimesters of pregnancy increased from 20% in 2002 to 27% in 2011. Use of four or more different types of prescription drug during at least one trimester increased from 8.4% in 2002 to 11.7% in 2011. Higher BMI, smoking during pregnancy, age under 25, carrying multiples, and being diagnosed with a chronic condition all significantly increased the odds of prescription drug use during pregnancy. Conclusions The observed increase in the number of prescriptions and number of different drugs being dispensed suggests a trend in prescribing practices with potentially important implications for mothers, their neonates, and caregivers. Monitoring of prescribing practices and further research into the safety of most commonly prescribed medications is crucial in better understanding risks and benefits to the fetus and the mother. PMID:26011706

  3. Salivary Testosterone Levels and Health Status in Men and Women in the British General Population: Findings from the Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)

    PubMed Central

    Macdowall, W.; Copas, A. J.; Tanton, C.; Keevil, B. G.; Lee, D. M.; Mitchell, K. R.; Field, N.; Sonnenberg, P.; Bancroft, J.; Mercer, C. H.; Wallace, A. M.; Johnson, A. M.; Wellings, K.; Wu, F. C. W.

    2016-01-01

    Context: Salivary T (Sal-T) measurement by liquid chromatography–tandem mass spectroscopy resents the opportunity to examine health correlates of Sal-T in a large-scale population survey. Objective: This study sought to examine associations between Sal-T and health-related factors in men and women age 18–74 years. Design and Setting: Morning saliva samples were obtained from participants in a cross-sectional probability-sample survey of the general British population (Natsal-3). Self-reported health and lifestyle questions were administered as part of a wider sexual health interview. Participants: Study participants included 1599 men and 2123 women. Methods: Sal-T was measured using liquid chromatography–tandem mass spectroscopy. Linear regression was used to examine associations between health factors and mean Sal-T. Results: In men, mean Sal-T was associated with a range of health factors after age adjustment, and showed a strong independent negative association with body mass index (BMI) in multivariable analysis. Men reporting cardiovascular disease or currently taking medication for depression had lower age-adjusted Sal-T, although there was no association with cardiovascular disease after adjustment for BMI. The decline in Sal-T with increasing age remained after adjustment for health-related factors. In women, Sal-T declined with increasing age; however, there were no age-independent associations with health-related factors or specific heath conditions with the exception of higher Sal-T in smokers. Conclusions: Sal-T levels were associated, independently of age, with a range of self-reported health markers, particularly BMI, in men but not women. The findings support the view that there is an age-related decline in Sal-T in men and women, which cannot be explained by an increase in ill health. Our results demonstrate the potential of Sal-T as a convenient measure of tissue androgen exposure for population research. PMID:27552539

  4. 'We are faced everywhere with a growing population': demographic change and the British state, 1955-64.

    PubMed

    O' Hara, Glen

    2004-01-01

    The early 1960s was a period of relative expansion for the welfare state, and the return to the use of planning techniques in macroeconomic policy. This has hitherto been explained by reference to a number of general causes. These have included party political electoral necessity, the need to gain popular support for the cold war by spreading the benefits of liberal capitalism, the power of welfare professionals, the growing realization that the post-war welfare state was not working as well as previously thought, and generational changes in politics and the civil service. Whilst not denying the importance of all these factors, this essay seeks to make clear the importance of another vital element in this story: the implications for the welfare state and the managed economy of the rise in the birth rate, and the perceived' population explosion', of the late 1950s and early 1960s. Statistical estimates are presented here that show just how large the implied expansion of the welfare state, and just how serious the pressure of a growing dependent population, would have been had the population predictions of the early 1930s proved to be accurate.

  5. The Impact of Clinical, Demographic and Risk Factors on Rates of HIV Transmission: A Population-based Phylogenetic Analysis in British Columbia, Canada

    PubMed Central

    Poon, Art F. Y.; Joy, Jeffrey B.; Woods, Conan K.; Shurgold, Susan; Colley, Guillaume; Brumme, Chanson J.; Hogg, Robert S.; Montaner, Julio S. G.; Harrigan, P. Richard

    2015-01-01

    Background. The diversification of human immunodeficiency virus (HIV) is shaped by its transmission history. We therefore used a population based province wide HIV drug resistance database in British Columbia (BC), Canada, to evaluate the impact of clinical, demographic, and behavioral factors on rates of HIV transmission. Methods. We reconstructed molecular phylogenies from 27 296 anonymized bulk HIV pol sequences representing 7747 individuals in BC—about half the estimated HIV prevalence in BC. Infections were grouped into clusters based on phylogenetic distances, as a proxy for variation in transmission rates. Rates of cluster expansion were reconstructed from estimated dates of HIV seroconversion. Results. Our criteria grouped 4431 individuals into 744 clusters largely separated with respect to risk factors, including large established clusters predominated by injection drug users and more-recently emerging clusters comprising men who have sex with men. The mean log10 viral load of an individual's phylogenetic neighborhood (composed of 5 other individuals with shortest phylogenetic distances) increased their odds of appearing in a cluster by >2-fold per log10 viruses per milliliter. Conclusions. Hotspots of ongoing HIV transmission can be characterized in near real time by the secondary analysis of HIV resistance genotypes, providing an important potential resource for targeting public health initiatives for HIV prevention. PMID:25312037

  6. A population-based study of antipsychotic prescription trends in children and adolescents in British Columbia, from 1996 to 2011.

    PubMed

    Ronsley, Rebecca; Scott, David; Warburton, William P; Hamdi, Ramsay D; Louie, Dianna Clare; Davidson, Jana; Panagiotopoulos, Constadina

    2013-06-01

    Objectifs : Établir les taux de prévalence des prescriptions d’antipsychotiques (AP) à des enfants et des adolescents de 18 ans et moins en Colombie-Britannique (C.-B.) de 1996 à 2011 selon l’âge, le sexe, le type d’AP, et le diagnostic primaire; et identifier les prescripteurs d’AP prédominants pour les enfants par formation de spécialité. Méthodes : Les données administratives du ministère de la Santé de la C.-B. ont servi à décrire les prescriptions d’AP à des adolescents de 18 ans ou moins. Des comparaisons ont été effectuées au moyen de la prévalence de la population selon le sexe, le groupe d’âge, les AP, la 9e édition de la Classification internationale des maladies, le diagnostic, et la spécialité du prescripteur. Résultats : De 1996 à 2011, le taux global de prévalence des prescriptions d’AP (de la première et de la deuxième génération) a augmenté 3,8 fois (1,66 à 6,37 par 1000 de population); les prescriptions d’AP de deuxième génération (ADG) ont augmenté 18,1 fois (0,33 à 5,98 par 1000 de population). L’augmentation la plus élevée de toutes les prescriptions d’AP a touché les jeunes hommes de 13 à 18 ans (3,3 à 14,4 par 1000 de population; soit 4,4 fois plus), suivie par des augmentations semblables chez les garçons de 6 à 12 ans (2,3 à 8,6 par 1000 de population; soit 3,7 fois plus) et chez les filles de 13 à 18 ans (2,8 à 10,7 par 1000 de population; soit 3,8 fois plus). En général, les 3 diagnostics les plus communs associés à toutes les prescriptions d’AP étaient les troubles dépressifs (12,8 %), l’instabilité de l’enfance (11,7 %), et les troubles névrotiques (11,1 %); toutefois, une variation a été observée dans la formation de spécialité du prescripteur. Parmi toutes les nouvelles prescriptions d’AP en 2010-2011, 38,6 %, 34,3 %, et 15,6 % ont été fournies par des psychiatres, des médecins de famille, et des pédiatres, respectivement. Conclusions : Il y a

  7. NEO Personality Inventory-Revised Normative Data that Distinguish U.S. Air Force AC-130 Gunship Sensor Operators from Enlisted Airmen Who Fail Training and Peers in the General Population

    DTIC Science & Technology

    2011-08-01

    incumbents) differ from the civilian general population, (b) assess how key personality traits (e.g., neuroticism , extraversion, openness...Relative to the Normative Population Sample of Adults (NEO PI-R Domain Scores: N= Neuroticism , E=Extraversion, O=Openness, A=Agreeableness, C...e.g., neuroticism , extraversion, openness, agreeableness, conscientiousness) for incumbents differ from enlisted airmen who failed training, (c

  8. Characterization of treatment and outcomes in a population-based cohort of patients with chronic lymphocytic leukemia referred for cytogenetic testing in British Columbia, Canada.

    PubMed

    Huang, Steven J; Lee, Lauren J; Gerrie, Alina S; Gillan, Tanya L; Bruyere, Helene; Hrynchak, Monica; Smith, Adam C; Karsan, Aly; Ramadan, Khaled M; Jayasundara, Kavisha S; Toze, Cynthia L

    2017-04-01

    This study evaluates outcomes in chronic lymphocytic leukemia (CLL) based on first-line therapy in a large consecutive population-based cohort of 669 patients with fluorescence in-situ hybridization (FISH) data in British Columbia, Canada during the period when chemoimmunotherapy was standard first-line treatment. When analyzed as a time-dependent variable, patients who required treatment (n=336) had a 4.7 times higher hazard of death than patients who did not (95% confidence interval 2.8-7.9, P<0.001). The majority of patients received fludarabine-rituximab (FR) in front-line. On multivariate Cox regression analysis, fludarabine-based first-line therapy predicted longer time-to-next-treatment (TTNT) (HR 0.53, 95% confidence interval 0.33-0.87, P=0.012) but no difference in overall survival (OS) compared to alkylator-based therapy. Deletion 17p was an independent predictor of worse TTNT and OS. The most common second-line treatments were cyclophosphamide-vincristine-prednisone-rituximab and FR. There was no difference in OS between patients retreated in second-line with the same first-line regimen (n=33) versus different regimen (n=113). In conclusion, front-line treatment with fludarabine leads to a longer time until need for next treatment than alkylator-based therapy; however, fludarabine or alkylator therapy produces no difference in OS. This study provides a historical baseline for the comparison of novel agents with standard treatments in CLL on a population-level.

  9. High Levels of Heterogeneity in the HIV Cascade of Care across Different Population Subgroups in British Columbia, Canada

    PubMed Central

    Lourenço, Lillian; Colley, Guillaume; Nosyk, Bohdan; Shopin, Dmitry; Montaner, Julio S. G.; Lima, Viviane D.

    2014-01-01

    Background The HIV cascade of care (cascade) is a comprehensive tool which identifies attrition along the HIV care continuum. We executed analyses to explicate heterogeneity in the cascade across key strata, as well as identify predictors of attrition across stages of the cascade. Methods Using linked individual-level data for the population of HIV-positive individuals in BC, we considered the 2011 calendar year, including individuals diagnosed at least 6 months prior, and excluding individuals that died or were lost to follow-up before January 1st, 2011. We defined five stages in the cascade framework: HIV ‘diagnosed’, ‘linked’ to care, ‘retained’ in care, ‘on HAART’ and virologically ‘suppressed’. We stratified the cascade by sex, age, risk category, and regional health authority. Finally, multiple logistic regression models were built to predict attrition across each stage of the cascade, adjusting for stratification variables. Results We identified 7621 HIV diagnosed individuals during the study period; 80% were male and 5% were <30, 17% 30–39, 37% 40–49 and 40% were ≥50 years. Of these, 32% were MSM, 28% IDU, 8% MSM/IDU, 12% heterosexual, and 20% other. Overall, 85% of individuals ‘on HAART’ were ‘suppressed’; however, this proportion ranged from 60%–93% in our various stratifications. Most individuals, in all subgroups, were lost between the stages: ‘linked’ to ‘retained’ and ‘on HAART’ to ‘suppressed’. Subgroups with the highest attrition between these stages included females and individuals <30 years (regardless of transmission risk group). IDUs experienced the greatest attrition of all subgroups. Logistic regression results found extensive statistically significant heterogeneity in attrition across the cascade between subgroups and regional health authorities. Conclusions We found that extensive heterogeneity in attrition existed across subgroups and regional health authorities along the HIV cascade of

  10. Do women spend longer on wait lists for coronary bypass surgery? Analysis of a population-based registry in British Columbia, Canada

    PubMed Central

    Levy, Adrian R; Sobolev, Boris G; Kuramoto, Lisa; Hayden, Robert; MacLeod, Stuart M

    2007-01-01

    Background Studies have shown patients who are delayed for surgical cardiac revascularization are faced with increased risks of symptom deterioration and death. This could explain the observation that operative mortality among persons undergoing coronary artery bypass surgery (CABG) is higher among women than men. However, in jurisdictions that employ priority wait lists to manage access to elective cardiac surgery, there is little information on whether women wait longer than men for CABG. It is therefore difficult to ascertain whether higher operative mortality among women is due to biological differences or to delayed access to elective CABG. Methods Using records from a population-based registry, we compared the wait-list time between women and men in British Columbia (BC) between 1990 and 2000. We compared the number of weeks from registration to surgery for equal proportions of women and men, after adjusting for priority, comorbidity and age. Results In BC in the 1990s, 9,167 patients aged 40 years and over were registered on wait lists for CABG and spent a total of 136,071 person-weeks waiting. At the time of registration for CABG, women were more likely to have a comorbid condition than men. We found little evidence to suggest that women waited longer than men for CABG after registration, after adjusting for comorbidity and age, either overall or within three priority groups. Conclusion Our findings support the hypothesis that higher operative mortality during elective CABG operations observed among women is not due to longer delays for the procedure. PMID:17683535

  11. Best of British: British Information Online.

    ERIC Educational Resources Information Center

    Ojala, Marydee

    1988-01-01

    Discusses the importance of British databases and information services to U.S. business searchers and describes several British databases and services. Topics covered include database contents, available search strategies, access from the United States, language differences, and dating problems. A directory of contacts is provided. (six…

  12. British Sign Name Customs

    ERIC Educational Resources Information Center

    Day, Linda; Sutton-Spence, Rachel

    2010-01-01

    Research presented here describes the sign names and the customs of name allocation within the British Deaf community. While some aspects of British Sign Language sign names and British Deaf naming customs differ from those in most Western societies, there are many similarities. There are also similarities with other societies outside the more…

  13. Costs of health resource utilization among HIV-positive individuals in British Columbia, Canada: Results from a population-level study

    PubMed Central

    Nosyk, B; Lima, V; Colley, G; Yip, B; Hogg, RS; Montaner, JSG

    2015-01-01

    Background Through delayed HIV disease progression, Highly Active Antiretroviral Therapy (HAART) may reduce direct medical costs, thus at least partially offsetting therapy costs. Recent findings regarding the secondary preventive benefits of HAART necessitate careful consideration of funding allocations for HIV/AIDS care. Our objective is to estimate non-HAART direct medical costs at different levels of disease progression and over time in British Columbia, Canada. Methods We considered the population of individuals with HIV/AIDS within a set of linked disease registries and health administrative databases (N=11,836) from 1996–2010. Costs of hospitalization, physician billing, diagnostic testing and non-HAART medications were calculated in 2010$CDN. Effects of covariates on quarterly costs were assessed with a two-part model with logit for probability of nonzero costs and a generalized linear model (GLM). Net effects of CD4 strata on direct non-HAART medical costs were evaluated over time during the study period. Results Compared to person-quarters in which CD4>500mm3, costs were $185(95% confidence interval:132,239) greater for CD4:350–500mm3, $441(366,516) greater for CD4 200–350mm3 and $1173(1051,1294) greater when CD4<200mm3. Prior to HIV care initiation, individuals incurred costs $385(283,487) greater than in periods with CD4>500mm3. Hospitalization comprised the majority of the increment in costs amongst those with no measured CD4. Evaluated at CD4 state conditional means, those with CD4<200mm3 incurred quarterly costs of $5781(4716,6846), versus $1307(1154,1460) (p<0.001) for CD4≥500mm3 in 2010. Conclusion Non-HAART direct medical costs were substantially lower for individuals during periods of sustained virologic suppression and high CD4 count. HIV treatment and prevention evaluations require detailed health resource use data to inform funding allocation decisions. PMID:25404425

  14. Targeted case finding for hepatitis B using dry blood spot testing in the British-Chinese and South Asian populations of the North-East of England.

    PubMed

    McPherson, S; Valappil, M; Moses, S E; Eltringham, G; Miller, C; Baxter, K; Chan, A; Shafiq, K; Saeed, A; Qureshi, R; Hudson, M; Bassendine, M F

    2013-09-01

    Chronic infection with the hepatitis B virus (HBV) is a frequent cause of cirrhosis and liver cancer. Targeted HBV screening is recommended by the Centre for Disease Control (CDC) and Prevention for subjects born in countries with >2% HBV prevalence. However, there are no UK guidelines. Here, we applied the (CDC) recommendations to the British-Chinese and British-South Asian community of North-East (NE) England. British-Chinese and South Asian subjects were invited to attend for HBV education and screening sessions held in community centres. Hepatitis B surface antigen (HBsAg) and hepatitis B core total antibody (HBcAb) were tested with dry blood spot tests. South Asians were also tested for hepatitis C antibody (HCVAb). A total of 1126 subjects (606 Chinese and 520 South Asian) were screened. Sixty-two (5.5%) were HBsAg positive. Ten of these reported a previous diagnosis of HBV. The prevalence of HBsAg positivity was 4.6% when previously diagnosed individuals were excluded. The HBsAg prevalence was significantly higher in the Chinese subjects compared with South Asians (8.7% VS. 1.7% P < 0.001). In Chinese subjects, HBsAg positivity was highest in subjects born in Vietnam (17.4%), followed by China (11%), Hong Kong (7.8%) and the UK (6.7%). Subjects from Pakistan had the highest HBsAg and HCV Ab prevalence in the South Asians (3.1% and 1.8%, respectively). Ten percentage of HBsAg positive patients who had follow-up assessment had active disease requiring antiviral treatment. Undiagnosed HBV infection was above the 2% threshold for screening suggested by the CDC in the British-Chinese and Pakistani community of NE England, which provides evidence for a UK HBV-targeted screening programme.

  15. Assessing the impact of human activities on British Columbia's estuaries.

    PubMed

    Robb, Carolyn K

    2014-01-01

    The world's marine and coastal ecosystems are under threat and single-sector management efforts have failed to address those threats. Scientific consensus suggests that management should evolve to focus on ecosystems and their human, ecological, and physical components. Estuaries are recognized globally as one of the world's most productive and most threatened ecosystems and many estuarine areas in British Columbia (BC) have been lost or degraded. To help prioritize activities and areas for regional management efforts, spatial information on human activities that adversely affect BC's estuaries was compiled. Using statistical analyses, estuaries were assigned to groups facing related threats that could benefit from similar management. The results show that estuaries in the most populated marine ecosections have the highest biological importance but also the highest impacts and the lowest levels of protection. This research is timely, as it will inform ongoing marine planning, land acquisition, and stewardship efforts in BC.

  16. How Does a Failing School Stop Failing?

    ERIC Educational Resources Information Center

    Warren-Gross, Laura

    2009-01-01

    The author's school had just been labeled a failing school by No Child Left Behind when its new principal arrived in the fall of 2007. In this demoralizing climate, teachers can get frustrated and choose to give up, or they can rise to the challenge, create a plan for improvement, and plunge into uncharted waters. This article discusses how the…

  17. Identification of Occupational Cancer Risks in British Columbia, Canada: A Population-Based Case—Control Study of 1,155 Cases of Colon Cancer

    PubMed Central

    Fang, Raymond; Le, Nhu; Band, Pierre

    2011-01-01

    Objective Cancer has been recognized to have environmental origin, but occupational cancer risk studies have not been fully documented. The objective of this paper was to identify occupations and industries with elevated colon cancer risk based on lifetime occupational histories collected from 15,463 incident cancer cases. Method A group matched case-control design was used. All cases were diagnosed with histologically proven colon cancers, with cancer controls being all other cancer sites, excluding rectum, lung and unknown primary, diagnosed at the same period of time from the British Columbia Cancer Registry. Data analyses were done on all 597 Canadian standard occupation titles and 1,104 standard industry titles using conditional logistic regression for matched data sets and the likelihood ratio test. Results Excess colon cancer risks was observed in a number of occupations and industries, particularly those with low physical activity and those involving exposure to asbestos, wood dusts, engine exhaust and diesel engine emissions, and ammonia. Discussion The results of our study are in line with those from the literature and further suggest that exposure to wood dusts and to ammonia may carry an increased occupational risk of colon cancer. PMID:22073015

  18. British super-shuttle

    NASA Astrophysics Data System (ADS)

    1984-10-01

    British Aerospace, the nationalized aerospace manufacturer, confirmed that a space shuttle of new design is indeed being studied, and that a model of the craft will be displayed. The British television network ITN had announced that secret plans were being prepared for the construction of a reusable horizontal takeoff super-shuttle, which could breathe atmospheric oxygen to supply its propulsion system. Retracting a first denial according to which the project existed merely as scribbles on the back of an envelope, a British Aerospace spokesperson declared that it was in fact a very serious study. The super-shuttle, called HOTOL (horizontal takeoff and landing), would be placed in orbit as a platform for satellite launching. The spokesperson further indicated that with a certain resemblance to the Concorde, it would be pilotless, remote controlled, and would allow frequent operations at short time intervals.

  19. Cross Sectional Associations between Socio-Demographic Factors and Cognitive Performance in an Older British Population: The European Investigation of Cancer in Norfolk (EPIC-Norfolk) Study

    PubMed Central

    Hayat, Shabina A.; Luben, Robert; Dalzell, Nichola; Moore, Stephanie; Anuj, Serena; Matthews, Fiona E.; Wareham, Nick; Brayne, Carol; Khaw, Kay-Tee

    2016-01-01

    Background Cognition covers a range of abilities, such as memory, response time and language, with tests assessing either specific or generic aspects. However differences between measures may be observed within the same individuals. Objective To investigate the cross-sectional association of cognitive performance and socio-demographic factors using different assessment tools across a range of abilities in a British cohort study. Methods Participants of the European Prospective Investigation of Cancer (EPIC) in Norfolk Study, aged 48–92 years, underwent a cognitive assessment between 2006 and 2011 (piloted between 2004 and 2006) and were investigated over a different domains using a range of cognitive tests. Results Cognitive measures were available on 8584 men and women. Though age, sex, education and social class were all independently associated with cognitive performance in multivariable analysis, different associations were observed for different cognitive tests. Increasing age was associated with increased risk of a poor performance score in all of the tests, except for the National Adult Reading Test (NART), an assessment of crystallized intelligence. Compared to women, men were more likely to have had poor performance for verbal episodic memory, Odds Ratio, OR = 1.99 (95% Confidence Interval, 95% CI 1.72, 2.31), attention OR = 1.62, (95% CI 1.39, 1.88) and prospective memory OR = 1.46, (95% CI 1.29, 1.64); however, no sex difference was observed for global cognition, OR = 1.07 (95%CI 0.93, 1.24). The association with education was strongest for NART, and weakest for processing speed. Conclusion Age, sex, education and social class were all independently associated with performance on cognitive tests assessing a range of different domains. However, the magnitude of associations of these factors with different cognitive tests differed. The varying relationships seen across different tests may help explain discrepancies in results reported in the current

  20. The 1985 British Physics Olympiad.

    ERIC Educational Resources Information Center

    Isenberg, Cyril

    1985-01-01

    Presents questions and answers to the 1985 British Physics Olympiad (BPhO) Competition. Comments about the competition (the second year of British participation) and the winners who went to Yugoslavia (and placed second behind the USSR) are included. (JN)

  1. The reliability of British Sign Language and English versions of the Clinical Outcomes in Routine Evaluation--Outcome Measure with d/Deaf populations in the UK: an initial study.

    PubMed

    Rogers, Katherine; Evans, Chris; Campbell, Malcolm; Young, Alys; Lovell, Karina

    2014-05-01

    Previous research has argued that the mental well-being of d/Deaf people is poorer than that of hearing populations. However, there is a paucity of valid and reliable mental health instruments in sign language that have been normalised with d/Deaf populations. The aim of this study was to determine the reliability of the Clinical Outcomes in Routine Evaluation - Outcome Measure (CORE-OM) with d/Deaf populations. A British Sign Language (BSL) version was produced using a team approach to forward translation, and a back-translation check. The CORE-OM was incorporated into an online survey, to be completed in either BSL or English, as preferred by the participant. From December 2010 to March 2011, data were collected from 136 d/Deaf people. Cronbach's α was used to measure the internal consistency of items in the CORE-OM. Comparisons were made between versions, including comparisons with the non-clinical hearing population (not in receipt of mental health services) in a previous study. The reliability of the overall score, as well as the non-risk items in both the BSL and English versions, was satisfactory. The internal reliability of each domain in the BSL version was good (Cronbach's α > 0.70) and comparable to the English version in the hearing population. This was true for most domains of the CORE-OM in the English version completed by d/Deaf people, although the Functioning domain had a relatively low α of 0.79 and the Risk domain had an α of only 0.66 This raised the question whether it is advisable to use a mental health assessment with d/Deaf populations that has been standardised with hearing populations. Nevertheless, this study has shown that it is possible to collect data from d/Deaf populations in the UK via the web (both in BSL and English), and an online BSL version of the CORE-OM is recommended for use with Deaf populations in the community.

  2. Prevent and "British Values"

    ERIC Educational Resources Information Center

    Kenny, Alex; Ghale, Baljeet

    2015-01-01

    At the recent National Union of Teachers' conference the role of the Prevent strategy and the introduction of "British Values" in the Office for Standards in Education, Children's Services and Skills framework emerged as key issues for delegates. Two of the speeches made at the conference are presented here.

  3. British nuclear policymaking

    SciTech Connect

    Bowie, C.J.; Platt, A.

    1984-01-01

    This study analyzes the domestic political, economic, and bureaucratic factors that affect the nuclear policymaking process in Great Britain. Its major conclusion is that, although there have been changes in that process in recent years (notably the current involvement of a segment of the British public in the debate about the deployment of intermediate-range nuclear forces), future British nuclear policymaking will remain much what it has been in the past. Three ideas are central to understanding British thinking on the subject: (1) Britain's long-standing resolve to have her own national nuclear force is largely traceable to her desire to maintain first-rank standing among the nations of the world in spite of loss of empire. (2) Financial considerations have always been important--so much so that they have usually dominated issues of nuclear policy. (3) The executive branch of government dominates the nuclear policymaking process but does not always present a united front. The United States heavily influences British nuclear policy through having supplied Britain since the late 1950s with nuclear data and components of nuclear weapon systems such as Polaris and Trident. The relationship works both ways since the U.S. depends on Britain as a base for deployment of both conventional and nuclear systems.

  4. Chronocentrism and British criminology.

    PubMed

    Rock, Paul

    2005-09-01

    Criminologists display a largely unexamined propensity to ignore writings that are more than fifteen or so years old, with evident consequences for the public presentation and validation of expert knowledge. A citation study was combined with detailed observations from British criminologists to ascertain quite how that disavowal of the past was accomplished.

  5. Who Really Failed? Commentary

    ERIC Educational Resources Information Center

    Maiuri, Katherine M.; Leon, Raul A.

    2012-01-01

    Scott Jaschik's (2010) article "Who Really Failed?" details the experience of Dominique Homberger, a tenured faculty member at Louisiana State University (LSU) who was removed from teaching her introductory biology course citing student complaints in regards to "the extreme nature" of the grading policy. This removal has…

  6. Use of the Internet for Sexual Health Among Sexually Experienced Persons Aged 16 to 44 Years: Evidence from a Nationally Representative Survey of the British Population

    PubMed Central

    Estcourt, Claudia S; Johnson, Anne M; Sonnenberg, Pam; Wellings, Kaye; Mercer, Catherine H

    2016-01-01

    Background Those who go online regarding their sexual health are potential users of new Internet-based sexual health interventions. Understanding the size and characteristics of this population is important in informing intervention design and delivery. Objective We aimed to estimate the prevalence in Britain of recent use of the Internet for key sexual health reasons (for chlamydia testing, human immunodeficiency virus [HIV] testing, sexually transmitted infection [STI] treatment, condoms/contraceptives, and help/advice with one’s sex life) and to identify associated sociodemographic and behavioral factors. Methods Complex survey analysis of data from 8926 sexually experienced persons aged 16-44 years in a 2010-2012 probability survey of Britain’s resident population. Prevalence of recent (past year) use of Internet sources for key sexual health reasons was estimated. Factors associated with use of information/support websites were identified using logistic regression to calculate age-adjusted odds ratios (AORs). Results Recent Internet use for chlamydia/HIV testing or STI treatment (combined) was very low (men: 0.31%; women: 0.16%), whereas 2.35% of men and 0.51% of women reported obtaining condoms/contraceptives online. Additionally, 4.49% of men and 4.57% of women reported recent use of information/support websites for advice/help with their sex lives. Prevalence declined with age (men 16-24 years: 7.7%; 35-44 years: 1.84%, P<.001; women 16-24 years: 7.8%; 35-44 years: 1.84%, P<.001). Use of information/support websites was strongly associated with men’s higher socioeconomic status (managerial/professional vs semiroutine/routine: AOR 1.93, 95% CI 1.27-2.93, P<.001). Despite no overall association with area-level deprivation, those in densely populated urban areas were more likely to report use of information/support websites than those living in rural areas (men: AOR 3.38, 95% CI 1.68-6.77, P<.001; women: AOR 2.51, 95% CI 1.34-4.70, P<.001). No

  7. Does the Intent to Irradiate the Internal Mammary Nodes Impact Survival in Women With Breast Cancer? A Population-Based Analysis in British Columbia

    SciTech Connect

    Olson, Robert A.; Woods, Ryan; Speers, Caroline; Lau, Jeffrey; Lo, Andrea; Truong, Pauline T.; Tyldesley, Scott; Olivotto, Ivo A.; Weir, Lorna

    2012-05-01

    Purpose: To determine the value of the intent to include internal mammary nodes (IMNs) in the radiation therapy (RT) volume for patients receiving adjuvant locoregional (breast or chest wall plus axillary and supraclavicular fossa) RT for breast cancer. Methods and Materials: 2413 women with node-positive or T3/4N0 invasive breast cancer, treated with locoregional RT from 2001 to 2006, were identified in a prospectively maintained, population-based database. Intent to include IMNs in RT volume was determined through review of patient charts and RT plans. Distant relapse free survival (D-RFS), breast cancer-specific survival (BCSS), and overall survival (OS) were compared between the two groups. Prespecified pN1 subgroup analyses were performed. Results: The median follow-up time was 6.2 years. Forty-one percent of study participants received IMN RT. The 5-year D-RFS for IMN inclusion and exclusion groups were 82% vs. 82% (p = 0.82), BCSS was 87% vs. 87% (p = 0.81), and OS was 85% vs. 83% (p = 0.06). In the pN1 subgroup, D-RFS was 90% vs. 88% (p = 0.31), BCSS was 94% vs. 92% (p = 0.18), and OS was 91% vs. 88% (p = 0.01). After potential confounding variables were controlled for, women who received IMN RT did not have significantly different D-RFS (hazard ratio [HR] = 1.02 (95% confidence interval [CI], 0.84-1.24; p = 0.85), BCSS (HR = 0.98 (95% CI, 0.79-1.22; p = 0.88), or OS (HR = 0.95; 95% CI, 0.78-1.15; p = 0.57). In the pN1 subgroup, IMN RT was associated with trends for improved survival that were not statistically significant: D-RFS (HR = 0.87; 95% CI, 0.63-1.22; p = 0.42), BCSS (HR = 0.85; 95% CI, 0.57-1.25; p = 0.39), and OS (HR = 0.78; 95% CI, 0.56-1.09; p = 0.14). Conclusions: After a median follow-up time of 6.2 years, although intentional IMN RT was not associated with a significant improvement in survival, this population-based study suggests that IMN RT may contribute to improved outcomes in selected patients with N1 disease.

  8. Neonatal screening for hereditary fructose intolerance: frequency of the most common mutant aldolase B allele (A149P) in the British population.

    PubMed

    James, C L; Rellos, P; Ali, M; Heeley, A F; Cox, T M

    1996-10-01

    Hereditary fructose intolerance (HFI) causes severe and sometimes fatal metabolic disturbances in infants and children but responds to dietary treatment. To determine the practicability of screening newborn infants for HFI, we have investigated the frequency of the most common and widespread mutant allele of aldolase B, A149P, in the neonatal population. The polymerase chain reaction was used to amplify aldolase B exon 5 genomic sequences in DNA present in dried blood specimens preserved on Guthrie cards. The A149P mutation was identified by discriminatory hybridisation to allele specific oligonucleotides and confirmed independently by digestion with the restriction endonuclease BsaHI. Twenty-seven A149P heterozygotes were identified by the molecular analysis of aldolase B genes in blood samples obtained from a random cohort of 2050 subjects born in 1994 and 1995, 1.32 +/- 0.49% (95% confidence level). Although no A149P homozygotes were identified, the data allow the frequency of 1 in 23,000 homozygotes for this allele to be predicted. Our findings have implications for establishing an interventional mass screening programme to identify newborn infants with HFI in the UK.

  9. Pathogenic Potential, Genetic Diversity, and Population Structure of Escherichia coli Strains Isolated from a Forest-Dominated Watershed (Comox Lake) in British Columbia, Canada

    PubMed Central

    Mazumder, Asit

    2014-01-01

    Escherichia coli isolates (n = 658) obtained from drinking water intakes of Comox Lake (2011 to 2013) were screened for the following virulence genes (VGs): stx1 and stx2 (Shiga toxin-producing E. coli [STEC]), eae and the adherence factor (EAF) gene (enteropathogenic E. coli [EPEC]), heat-stable (ST) enterotoxin (variants STh and STp) and heat-labile enterotoxin (LT) genes (enterotoxigenic E. coli [ETEC]), and ipaH (enteroinvasive E. coli [EIEC]). The only genes detected were eae and stx2, which were carried by 37.69% (n = 248) of the isolates. Only eae was harbored by 26.74% (n = 176) of the isolates, representing potential atypical EPEC strains, while only stx2 was detected in 10.33% (n = 68) of the isolates, indicating potential STEC strains. Moreover, four isolates were positive for both the stx2 and eae genes, representing potential EHEC strains. The prevalence of VGs (eae or stx2) was significantly (P < 0.0001) higher in the fall season, and multiple genes (eae plus stx2) were detected only in fall. Repetitive element palindromic PCR (rep-PCR) fingerprint analysis of 658 E. coli isolates identified 335 unique fingerprints, with an overall Shannon diversity (H′) index of 3.653. Diversity varied among seasons over the years, with relatively higher diversity during fall. Multivariate analysis of variance (MANOVA) revealed that the majority of the fingerprints showed a tendency to cluster according to year, season, and month. Taken together, the results indicated that the diversity and population structure of E. coli fluctuate on a temporal scale, reflecting the presence of diverse host sources and their behavior over time in the watershed. Furthermore, the occurrence of potentially pathogenic E. coli strains in the drinking water intakes highlights the risk to human health associated with direct and indirect consumption of untreated surface water. PMID:25548059

  10. Pathogenic potential, genetic diversity, and population structure of Escherichia coli strains isolated from a forest-dominated watershed (Comox Lake) in British Columbia, Canada.

    PubMed

    Chandran, Abhirosh; Mazumder, Asit

    2015-03-01

    Escherichia coli isolates (n = 658) obtained from drinking water intakes of Comox Lake (2011 to 2013) were screened for the following virulence genes (VGs): stx1 and stx2 (Shiga toxin-producing E. coli [STEC]), eae and the adherence factor (EAF) gene (enteropathogenic E. coli [EPEC]), heat-stable (ST) enterotoxin (variants STh and STp) and heat-labile enterotoxin (LT) genes (enterotoxigenic E. coli [ETEC]), and ipaH (enteroinvasive E. coli [EIEC]). The only genes detected were eae and stx2, which were carried by 37.69% (n = 248) of the isolates. Only eae was harbored by 26.74% (n = 176) of the isolates, representing potential atypical EPEC strains, while only stx2 was detected in 10.33% (n = 68) of the isolates, indicating potential STEC strains. Moreover, four isolates were positive for both the stx2 and eae genes, representing potential EHEC strains. The prevalence of VGs (eae or stx2) was significantly (P < 0.0001) higher in the fall season, and multiple genes (eae plus stx2) were detected only in fall. Repetitive element palindromic PCR (rep-PCR) fingerprint analysis of 658 E. coli isolates identified 335 unique fingerprints, with an overall Shannon diversity (H') index of 3.653. Diversity varied among seasons over the years, with relatively higher diversity during fall. Multivariate analysis of variance (MANOVA) revealed that the majority of the fingerprints showed a tendency to cluster according to year, season, and month. Taken together, the results indicated that the diversity and population structure of E. coli fluctuate on a temporal scale, reflecting the presence of diverse host sources and their behavior over time in the watershed. Furthermore, the occurrence of potentially pathogenic E. coli strains in the drinking water intakes highlights the risk to human health associated with direct and indirect consumption of untreated surface water.

  11. Accidental Deaths Among British Columbia Indians

    PubMed Central

    Schmitt, N.; Hole, L. W.; Barclay, W. S.

    1966-01-01

    A statistical and epidemiological review of British Columbia native Indian and non-Indian mortality revealed that accidents were the leading cause of death among Indians but ranked only fourth among non-Indians. Comparison of accidental death rates by age and sex showed that, without exception, the rates among Indians were considerably higher than the corressponding rates for non-Indians. While the Indians represented some 2% of the total population of British Columbia, they accounted for over 10% of the total accident fatalities, 29% of drownings, and 21% of fatal burns. Socioeconomic, environmental and psychosocial factors and excessive drinking are considered the chief causes responsible for this rather unusual epidemiological phenomenon. This study revealed certain hazardous conditions which are specific to the Indian's present way of life. In the authors' opinion the recognition of these specific hazards is imperative for the planning of effective preventive campaigns. PMID:5902238

  12. Indians Repulse British With Rocket

    NASA Technical Reports Server (NTRS)

    2004-01-01

    During the early introduction of rockets to Europe, they were used only as weapons. Enemy troops in India repulsed the British with rockets. Later, in Britain, Sir William Congreve developed a rocket that could fire to about 9,000 feet. The British fired Congreve rockets against the United States in the War of 1812.

  13. When Fundoplication Fails

    PubMed Central

    Smith, C Daniel; McClusky, David A.; Rajad, Murad Abu; Lederman, Andrew B.; Hunter, John G.

    2005-01-01

    Objective: The largest series in the literature dealing with redo fundoplication was presented and published in 1999 and included 100 patients. Herein we update this initial series of 100, with 207 additional patients who have undergone redo fundoplication (n = 307). Summary Background Data: Increasing numbers of patients are failing esophagogastric fundoplication and requiring redo procedures. Data regarding the nature of these failures have been scant. Methods: Data on all patients undergoing foregut surgery are collected prospectively. Between 1991 and 2004, 307 patients underwent redo fundoplication for the management of anatomic complications or recurrent GERD. Statistical analysis was performed with multiple χ2 and Mann-Whitney U analyses, as well as ANOVA. Results: Between 1991 and 2004, 1892 patients underwent primary fundoplication for GERD (1734) or paraesophageal hernia (158). Of these, 54 required redo fundoplication (2.8%). The majority of failures (73%) were managed within 2 years of the initial operation (P = 0.0001). The mechanism of failure was transdiaphragmatic wrap herniation in 33 of 54 (61%). In the 231 patients who underwent fundoplication elsewhere, 109 had transdiaphragmatic herniation (47%, P = NS). In this group of 285 patients, 22 (8%) required another redo (P = NS). The majority of the procedures were initiated laparoscopically (240/307, 78%), with 20 converted (8%). Overall mortality was 0.3%. Conclusions: Failure of fundoplication is unusual in experienced hands. Most are managed within 2 years of the initial operation. Wrap herniation has now become the most common mechanism of failure requiring redo. Redo fundoplication was successful in 93% of patients, and most could be safely handled laparoscopically. PMID:15912035

  14. History of British Space Science

    NASA Astrophysics Data System (ADS)

    Massie, Harrie; Robins, M. O.

    2009-12-01

    1. The scientific background; 2. The technical background; 3. The initiation of the Skylark rocket programme; 4. Post IGY developments; 5. The Ariel programme; 6. The European Space Research Organisation; 7. Commonwealth co-operation in space research; 8. Smaller rockets for scientific purposes - Skua and Petrel; 9. Attitude controlled Skylark rockets; 10. The Trend Committee and the Science Research Council; 11. The transformation of ESRO into ESA; 12. The Space Science Committee for Europe; 13. Scientific studies by British space scientists I; 14. Scientific studies by British space scientists II; 15. The contribution from British space scientists to astronomy; 16. Concluding remarks; Appendices; Annexes.

  15. Nurse education in the British armed forces.

    PubMed

    Carter, Chris; Finnegan, Alan P

    2014-10-21

    Defence nurses form the largest registered specialty in the UK defence medical services. Once qualified, defence nurses maintain and develop their nursing and clinical skills in appropriate healthcare settings, and can be deployed in operational environments such as Afghanistan. Workforce planning and staffing establishment levels are defined to meet the needs of British armed forces, allies and, potentially, local populations. Since the workforce is geographically dispersed, deployed or undertaking non-clinical duties, there are constraints on nurses' attempts to maintain basic skills and access continuing professional development. This article explores the concept and the developing role of defence nurse lecturers in improving educational support for defence nurses.

  16. Oil and the British economy

    SciTech Connect

    Atkinson, F.; Hall, S.

    1983-01-01

    Despite the 1976 discovery of North Sea oil, the British economy has floundered in the early 1980s. To uncover the reasons behind this predicament, the authors examine the North Sea oil sector, show the impact of its recent development on the British economy, and analyze the automatic responses of an economy to the development of such a new sector, the ''Kay debate,'' and the experience of six other countries with oil and the manufacturing industry.

  17. Can Failing Schools Be Fixed?

    ERIC Educational Resources Information Center

    Brady, Ronald C.

    2003-01-01

    The No Child Left Behind Act of 2001 (NCLB) requires states and school districts to act aggressively to turn around failing schools. NCLB lists 31 different interventions of varying degrees of severity that are available to state and local policymakers when faced with schools whose students fail to make sufficient academic progress and sets forth…

  18. Comparison of British and French expatriate doctors’ characteristics and motivations

    PubMed Central

    Quantin, Catherine; Abbas, Rachid; Hagi, Mathieu; Breton, Gwenaelle Le; Romestaing, M; Carnet, Dider

    2012-01-01

    Objective The aim of this study was to analyse the migration of doctors between the UK and France, in an attempt to identify the reasons for these migrations. Design This was a cross-sectional study conducted using a self-completed questionnaire. Setting The questionnaire was sent to all British doctors practising in France and to all French doctors practising in the UK. Participants The doctors were identified, thanks to official data of the National Medical Councils. There were 244 French doctors practising in the UK and 86 British doctors practising in France. Outcome measures A questionnaire was specifically developed for the study to determine the reasons why doctors moved to the other country and their level of satisfaction with regard to their expatriation. Results A total of 98 French doctors (of 244) and 40 British doctors (of 86) returned the questionnaire. The motivations of the two studied populations were different: French doctors were attracted by the conditions offered by the National Health Service, whereas British doctors were more interested in opportunities for career advancement, moved to join a husband or wife or to benefit from favourable environmental conditions. Overall, the doctors who responded considered the expatriation a satisfactory experience. After expatriation, 84% of French doctors were satisfied with their new professional situation compared with only 58% of British doctors. Conclusions This study, which is the first of its kind and based on representative samples, has led to a clearer understanding of the migration of doctors between France and the UK. PMID:23192244

  19. Population.

    ERIC Educational Resources Information Center

    King, Pat; Landahl, John

    This pamphlet has been prepared in response to a new problem, a rapidly increasing population, and a new need, population education. It is designed to help teachers provide their students with some basic population concepts with stress placed on the elements of decision making. In the first section of the pamphlet, some of the basic concepts of…

  20. [Population].

    PubMed

    1979-01-01

    Data on the population of Venezuela between 1975 and 1977 are presented in descriptive tables and graphs. Information is included on the employed population according to category, sex, and type of economic activity, and by sex, age, and area on the employment rate and the total, the economically active, and the unemployed population.

  1. Instructor Training on British Railways

    ERIC Educational Resources Information Center

    Gibson, J. D.

    1970-01-01

    The value of instructor training was recognized by British Railways as early as 1950 with the setting up of a training center at Darlington. This article shows the results of this continuous training experience in the benefits to be obtained from re-appraisal techniques and practical work. (Author/EB)

  2. British Industrial Libraries Before 1939

    ERIC Educational Resources Information Center

    Marshall, Margaret R.

    1972-01-01

    British industrial firm libraries are traced from their beginnings till 1939, by which date they had spread to many branches of industry and had been recognized as an important part of the industrial and library worlds, thus establishing standard patterns of work. The origins and significance of Aslib are discussed. (27 references) (Author/NH)

  3. Integrated geoscientific exploration at Meager Creek British Columbia (1982)

    SciTech Connect

    Harvey, C.C.; Leach, T.M.; Macdonald, W.J.P.

    1983-09-01

    The application of an integrated geoscientific approach to the exploration stage of the Meager Creek geothermal project in British Columbia is discussed. The approach has provided a preliminary assessment of the resource potential of the area. The work has included geological reconnaissance, geophysics, and an extensive geochemical sampling program. The surveys have indicated that a geothermal resource exists on the south side of the Meager Complex an outflows down the Meager Valley. Geophysical surveys and drilling operations failed to identify evidence of an outflow from an active high-temperature geothermal system on the north side of the Meager complex.

  4. Making processing fail-safe

    SciTech Connect

    Freiburghouse, R.

    1982-05-01

    The author describes the Stratus/32 multiprocessor, a fault-tolerant system for commercial applications which supports on-line transaction processing, batch processing, word processing and interactive program development. It uses a combination of hardware and software that provides continuous processing of user programs during computer failure without checkpoint/restart programming at the user or system level. Central to the system's fail-safe operation are processing modules, each of which has redundant logic and communication paths, logic and CPU boards and main and disk memory. Twin components operate in parallel with each other; when one fails, its partner carries on.

  5. Immigrant Incorporation in American Cities: Contextual Determinants of Irish, German and British Intermarriage in 1880

    PubMed Central

    Logan, John R.; Shin, Hyoung-jin

    2013-01-01

    This study adds to a growing body of research on the contextual determinants of marriage choice and provides new information on ethnic intermarriage in the late 19th Century. Census microdata for 66 major cities in 1880 are used to estimate a multilevel model of assortative mating of Irish, German, and British immigrants. Results demonstrate that marital choices made by individuals are significantly affected by the local urban context where they live. In addition the very large disparity in endogamy between the British and other groups can mainly be attributed to the smaller size of the British population in these cities. PMID:24259757

  6. Population.

    ERIC Educational Resources Information Center

    International Planned Parenthood Federation, London (England).

    In an effort to help meet the growing interest and concern about the problems created by the rapid growth of population, The International Planned Parenthood Federation has prepared this booklet with the aim of assisting the study of the history and future trends of population growth and its impact on individual and family welfare, national,…

  7. Is journalism failing on climate?

    NASA Astrophysics Data System (ADS)

    Rahmstorf, Stefan

    2012-12-01

    How can we build a reliable and affordable energy supply based on renewables? How rapidly do we need to cut greenhouse gas emissions to keep climate change within manageable bounds? What does it take to maintain a stable common currency of different nations? These are just a few examples of questions that are critical for our future and that require an understanding of complex systems—the energy system, the climate system, the financial system. Finding sound answers to these questions requires sophisticated scientific analysis and expert knowledge; a lay person's intuition will clearly not suffice. Yet, decisions in a democracy are (and should be!) taken by politicians and the voting public who are not usually scientific experts. Hence the well-being of our societies—and even more so the living conditions of future generations, which are defined by the decisions we take today—depends on the wider public being well informed about the state of scientific knowledge and discourse. The media are the most important means by which lay people obtain their information about science. Good science journalism is therefore a decisive factor for the long-term success of modern society. Good science journalism clearly must be critical journalism, and it requires journalists who know what is what, who can put things into a perspective, and who are able to make well-informed judgements. After all, the role of science journalism is not simply to act as a 'translator' who conveys the findings of scientists in a language understandable to lay people. Rather, good science journalism will provide the public with a realistic impression of what is well established in science and what are current 'hot topics', uncertainties and controversies. It will also discuss the methods and social context of the scientific endeavour. There is ample evidence that in the area of climate science, journalism too often is failing to deliver this realistic picture to its audience, despite many good

  8. A Failed Counterinsurgency Strategy: The British Southern Campaign - 1780-1781 Are There Lessons for Today?

    DTIC Science & Technology

    2007-11-02

    Declaratory Act, Enacted 1766, which reasserted the right of Parliament to tax the colonies, the Townsend Act, Enacted 1768 , Partial Repeal 1770 with...the Tea Tax remaining and was a primary cause of the Boston Tea Party in December 1773, and finally the Coercive Acts, Enacted 1774 17 Cook, pg 75. 18

  9. US Intervention in Failed States: Bad Assumptions=Poor Outcomes

    DTIC Science & Technology

    2002-01-01

    NATIONAL DEFENSE UNIVERSITY NATIONAL WAR COLLEGE STRATEGIC LOGIC ESSAY US INTERVENTION IN FAILED STATES: BAD ASSUMPTIONS = POOR ...2002 2. REPORT TYPE 3. DATES COVERED 00-00-2002 to 00-00-2002 4. TITLE AND SUBTITLE US Intervention in Failed States: Bad Assumptions= Poor ...country remains in the grip of poverty , natural disasters, and stagnation. Rwanda Rwanda, another small African country, is populated principally

  10. The Past is a Foreign Country -- Understanding the British Approach to Counterinsurgency

    DTIC Science & Technology

    2013-05-23

    of operations in the Philippines and El Salvador . However the narrative of British success, achieved by a reliance on minimum force and obeisance...British with significant loss of life amongst the local population. A fine introduction to the subject can be found in Conrad Wood, The Moplah...required nation building, as it desired the design of a nation along certain fixed, pre-ordained lines (democracy, human rights and so on), rather

  11. Identification of metapopulation dynamics among Northern Goshawks of the Alexander Archipelago, Alaska, and Coastal British Columbia

    USGS Publications Warehouse

    Sonsthagen, Sarah A.; McClaren, Erica L.; Doyle, Frank I.; Titus, K.; Sage, George K.; Wilson, Robert E.; Gust, Judy R.; Talbot, Sandra L.

    2012-01-01

    Northern Goshawks occupying the Alexander Archipelago, Alaska, and coastal British Columbia nest primarily in old-growth and mature forest, which results in spatial heterogeneity in the distribution of individuals across the landscape. We used microsatellite and mitochondrial data to infer genetic structure, gene flow, and fluctuations in population demography through evolutionary time. Patterns in the genetic signatures were used to assess predictions associated with the three population models: panmixia, metapopulation, and isolated populations. Population genetic structure was observed along with asymmetry in gene flow estimates that changed directionality at different temporal scales, consistent with metapopulation model predictions. Therefore, Northern Goshawk assemblages located in the Alexander Archipelago and coastal British Columbia interact through a metapopulation framework, though they may not fit the classic model of a metapopulation. Long-term population sources (coastal mainland British Columbia) and sinks (Revillagigedo and Vancouver islands) were identified. However, there was no trend through evolutionary time in the directionality of dispersal among the remaining assemblages, suggestive of a rescue-effect dynamic. Admiralty, Douglas, and Chichagof island complex appears to be an evolutionarily recent source population in the Alexander Archipelago. In addition, Kupreanof island complex and Kispiox Forest District populations have high dispersal rates to populations in close geographic proximity and potentially serve as local source populations. Metapopulation dynamics occurring in the Alexander Archipelago and coastal British Columbia by Northern Goshawks highlight the importance of both occupied and unoccupied habitats to long-term population persistence of goshawks in this region.

  12. Segmented Coil Fails In Steps

    NASA Technical Reports Server (NTRS)

    Stedman, Ronald S.

    1990-01-01

    Electromagnetic coil degrades in steps when faults occur, continues to operate at reduced level instead of failing catastrophically. Made in segments connected in series and separated by electrically insulating barriers. Fault does not damage adjacent components or create hazard. Used to control valves in such critical applications as cooling systems of power generators and chemical process equipment, where flammable liquids or gases handled. Also adapts to electrical control of motors.

  13. CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines.

    PubMed

    Muraro, Manuele Giuseppe; Mele, Valentina; Däster, Silvio; Han, Junyi; Heberer, Michael; Cesare Spagnoli, Giulio; Iezzi, Giandomenica

    2012-08-01

    Increasing evidence that cancers originate from small populations of so-called cancer stem cells (CSCs), capable of surviving conventional chemotherapies and regenerating the original tumor, urges the development of novel CSC-targeted treatments. Screening of new anticancer compounds is conventionally conducted on established tumor cell lines, providing sufficient material for high-throughput studies. Whether tumor cell lines might comprise CSC populations resembling those of primary tumors, however, remains highly debated. We have analyzed the expression of defined phenotypic profiles, including CD133+, CD166+CD44+, and CD24+CD44+, reported as CSC-specific in human primary colorectal cancer (CRC), on a panel of 10 established CRC cell lines and evaluated their correlation with CSC properties. None of the putative CSC phenotypes consistently correlated with stem cell-like features, including spheroid formation ability, clonogenicity, aldehyde dehydrogenase-1 activity, and side population phenotype. Importantly, CRC cells expressing putative CSC markers did not exhibit increased survival when treated with chemotherapeutic drugs in vitro or display higher tumorigenicity in vivo. Thus, the expression of CD133 or the coexpression of CD166/CD44 or CD24/CD44 did not appear to reliably identify CSC populations in established CRC cell lines. Our findings question the suitability of cell lines for the screening of CSC-specific therapies and underline the urgency of developing novel platforms for anticancer drug discovery.

  14. Checklist of British and Irish Hymenoptera - Platygastroidea

    PubMed Central

    Buhl, Peter N.; Notton, David G.

    2016-01-01

    Abstract Background A revised checklist of the British and Irish Platygastroidea (Platygastridae) substantially updates the previous comprehensive checklist, dating from 1978. Distribution data (i.e. occurrence in England, Scotland, Wales, Ireland and the Isle of Man) is reported where known. New information A total of 381 British and Irish Platygastroidea represents a 47% increase on the number of British and Irish species reported in 1978. PMID:27279762

  15. Request Strategies in British English and Japanese.

    ERIC Educational Resources Information Center

    Fukushima, Saeko

    1996-01-01

    Tests request strategies used by speakers of Japanese and British English in two culturally neutral situations likely to trigger a request. Concludes that the degree of imposition goes on a par with the number of politeness strategies but that there are differences in the types of strategies used: the British use conventional forms and supportive…

  16. The Current Canon in British Romantics Studies.

    ERIC Educational Resources Information Center

    Linkin, Harriet Kramer

    1991-01-01

    Describes and reports on a survey of 164 U.S. universities to ascertain what is taught as the current canon of British Romantic literature. Asserts that the canon may now include Mary Shelley with the former standard six major male Romantic poets, indicating a significant emergence of a feminist perspective on British Romanticism in the classroom.…

  17. British Columbia Transfer TIPS. Second Edition Revised

    ERIC Educational Resources Information Center

    Finlay, Finola, Ed.; Karlinski, Jean, Ed.

    2005-01-01

    BCTransfer TIPS is a user friendly document outlining how transfer between British Columbia (BC) post-secondary institutions works. It includes tips, student quotes, scenarios, a personal plan and checklist. Information in this document can only be reproduced with permission from the British Columbia Council on Admissions and Transfer (BCCAT.)

  18. British Children's Books in the Twentieth Century.

    ERIC Educational Resources Information Center

    Eyre, Frank

    A revised and expanded version of an earlier study of modern British children's literature (1952), this latest edition begins with an introductory section on the historical development of children's literature and follows with chapters examining the main trends in British children's books from 1900 to the present day. Special attention is given to…

  19. The Contemporaneity of the British Survey.

    ERIC Educational Resources Information Center

    Dodson, Charles Brooks

    The seeming remoteness of material studied in a British literature survey course can be frustrating for the teacher. Students may find little relevance in the story of Beowulf or the descriptions of Gulliver's voyages. However, instructors can highlight the contemporaneity of British literary texts by drawing parallels to modern times. For…

  20. Providing a Background for British Literature.

    ERIC Educational Resources Information Center

    DeLuca, Diana Macintyre

    One consequence of teaching British literature far away from British shores is the loss of intimacy that comes from a shared culture. American teachers can help bring Britain into their classrooms by requesting audiovisual aids from the various museums and galleries in Britain that are willing to supply material. Among such sources are (1) Walton…

  1. Utilisation of British University Research Reactors.

    ERIC Educational Resources Information Center

    Duncton, P. J.; And Others

    British experience relating to the employment of university research reactors and subcritical assemblies in the education of nuclear scientists and technologists, in the training of reactor operators and for fundamental pure and applied research in this field is reviewed. The facilities available in a number of British universities and the uses…

  2. Indian Education Programs in British Columbia.

    ERIC Educational Resources Information Center

    Kelly, Reg

    The British North America Act of 1867, the founding constitution of Canada, provides that all matters pertaining to Indians and Indian lands are under Federal jurisdiction. Because of this, the province of British Columbia (BC) has not felt it could do much for native peoples and little attention has been paid to the extension of provincial…

  3. The Making of a Moral British Bangladeshi

    ERIC Educational Resources Information Center

    Zeitlyn, Benjamin

    2014-01-01

    This article traces changing notions of a moral upbringing among British Bangladesh families in London. It reviews ideas of the making of a moral person ("manush corano") in Bangladesh and contrasts those with contemporary practices and ideas about the good child in London. It argues that in London, British Bangladeshis have embraced a…

  4. British African Caribbean Women and Depression

    ERIC Educational Resources Information Center

    Adkison-Bradley, Carla; Maynard, Donna; Johnson, Phillip; Carter, Stephaney

    2009-01-01

    Depression is a common condition among women in the United Kingdom. However, little is known about the context of depression among British African Caribbean women. This article offers a preliminary discussion regarding issues and information pertaining to depression among British African Caribbean women. Characteristics and symptoms of depression…

  5. Integrated Curriculum Programs in British Columbia

    ERIC Educational Resources Information Center

    Johnston, Julie

    2011-01-01

    In this article, the author discusses British Columbia's integrated curriculum programs (ICPs). In this province of sea and mountains, outdoor adventures figure prominently in its ICPs--with a healthy dose of environmental and sustainability education mixed in. The author presents five examples from British Columbia's ICPs: (1) Earthquest Outdoor…

  6. Physical activity and dietary behaviour in a population-based sample of British 10-year old children: the SPEEDY study (Sport, Physical activity and Eating behaviour: Environmental Determinants in Young people)

    PubMed Central

    van Sluijs, Esther MF; Skidmore, Paula ML; Mwanza, Kim; Jones, Andrew P; Callaghan, Alison M; Ekelund, Ulf; Harrison, Flo; Harvey, Ian; Panter, Jenna; Wareham, Nicolas J; Cassidy, Aedin; Griffin, Simon J

    2008-01-01

    Background The SPEEDY study was set up to quantify levels of physical activity (PA) and dietary habits and the association with potential correlates in 9–10 year old British school children. We present here the analyses of the PA, dietary and anthropometry data. Methods In a cross-sectional study of 2064 children (926 boys, 1138 girls) in Norfolk, England, we collected anthropometry data at school using standardised procedures. Body mass index (BMI) was used to define obesity status. PA was assessed with the Actigraph accelerometer over 7 days. A cut-off of ≥ 2000 activity counts was used to define minutes of moderate-to-vigorous PA (MVPA). Dietary habits were assessed using the Health Behaviour in School Children food questionnaire. Weight status was defined using published international cut-offs (Cole, 2000). Differences between groups were assessed using independent t-tests for continuous data and chi-squared tests for categorical data. Results Valid PA data (>500 minutes per day on ≥ 3 days) was available for 1888 children. Mean (± SD) activity counts per minute among boys and girls were 716.5 ± 220.2 and 635.6 ± 210.6, respectively (p < 0.001). Boys spent an average of 84.1 ± 25.9 minutes in MVPA per day compared to 66.1 ± 20.8 among girls (p < 0.001), with an average of 69.1% of children accumulating 60 minutes each day. The proportion of children classified as overweight and obese was 15.0% and 4.1% for boys and 19.3% and 6.6% for girls, respectively (p = 0.001). Daily consumption of at least one portion of fruit and of vegetables was 56.8% and 49.9% respectively, with higher daily consumption in girls than boys and in children from higher socioeconomic backgrounds. Conclusion Results indicate that almost 70% of children meet national PA guidelines, indicating that a prevention of decline, rather than increasing physical activity levels, might be an appropriate intervention target. Promotion of daily fruit and vegetable intake in this age group is

  7. Risk of malaria in British residents returning from malarious areas.

    PubMed Central

    Phillips-Howard, P A; Radalowicz, A; Mitchell, J; Bradley, D J

    1990-01-01

    OBJECTIVES--To identify which British residents travelling abroad are at greatest risk of malaria infection, and to determine the efficacy of malaria chemoprophylaxis for preventing P falciparum infections in tropical Africa. DESIGN--Prospective cohort study (case-base linkage) with routine national surveillance systems. Denominators (base population) were obtained from monitoring a random sample of returning British travellers with the international passenger survey. Numerators (cases) were obtained from reports of malaria infections in British residents, through the Malaria Reference Laboratory network. SETTING--International passenger survey conducted at passport control of international airports in Britain. Malaria reports received nationally were collated centrally in London. SUBJECTS--2948 British residents (0.2%) returning to Britain in 1987 randomly selected and questioned and 1052 British residents with microscopically confirmed malaria infections in 1987, whose case reports were reviewed and on whom additional data were collected by postal survey. MAIN OUTCOME MEASURES--Annual incidence subdivided by categories of risk. Chemoprophylactic efficacy for east and west Africa by principal regimens and compliance. RESULTS--Annual rates of reported infection per 100,000 travellers to Oceania were 4100; to west and east Africa were 375 and 172 respectively; to Latin America, the Far East, and the Middle East were 12, 2, and 1 respectively. Immigrants visiting friends and relatives in Ghana and Nigeria were at greatest risk (1303 and 952 per 100,000 respectively) in west Africa. Business travellers to Kenya experienced the highest attack rates in east Africa (465 per 100,000). Age-sex specific attack rates varied by region. No prophylaxis was reported to have been used by 23% of British visitors to west Africa, 17% to east Africa, 46% to central or southern Africa, and 58% visiting south Asia. The efficacy of chloroquine plus proguanil against P falciparum

  8. Developments in British environmental law

    SciTech Connect

    Williams, D.G.T.

    1984-07-01

    Decisions on whether or not to build nuclear power plants are increasingly settled in the courts because of conflicting interests in the growth of electric power demand and environmental protection that has led to a breakdown in public order. Lawyers share the same sense of bewilderment as lay people over nuclear as well as noise, smoke, and other types of environmental questions. The author reviews British criminal and civil law to see how the courts have dealt with pollution issues in the past. Public inquiry over a proposed development has triggered many of Britain's major law and environment problems, the Windscale inquiry being a notable example. A reluctance to legislate is an underlying factor in the trend toward inquiry and litigation. 139 references.

  9. British surgical aid to Jordan

    PubMed Central

    Boyd, N. A.; Barry, N. A.; Davies, A. K.

    1971-01-01

    The surgical commitment of No. 2 Field Hospital, R.A.M.C., during its stay in Jordan is presented. The majority of patients that were admitted had sustained war wounds, many of which were infected due to the delay in treatment. The difficulties encountered in their subsequent management are discussed. Special reference is made to the use of ketamine (Ketalar) and mafenide acetate (Sulphamylon) in the treatment of those burns cases under our care. It is the first time for many years that a British field hospital has been employed in an active rôle. ImagesFig. 1Fig. 3Fig. 4Fig. 8Fig. 11Fig. 12Fig. 13Fig. 14Fig. 2Fig. 5Fig. 6Fig. 7Fig. 9Fig. 10 PMID:5114910

  10. Medical Refugees and the Modernisation of British Medicine, 1930–1960

    PubMed Central

    Weindling, Paul

    2015-01-01

    Summary This paper reappraises the position of medical refugees in Britain between the 1930s and 1950s. Advocates of reforming British medicine in terms of its knowledge base and social provision emerged as strongly supportive of the medical refugees. By way of contrast, an élite in the British Medical Association attempted to exercise a controlling regime through the Home Office Advisory Committee. The effects of these divisions are gauged by reconstructing the complete spectrum of refugees as a total population. Applying this methodology of population reconstruction provides a corrective to the notion of a cohesive ‘medical establishment’ exercising rigid and discriminatory controls. PMID:26166948

  11. Failed State: A New (Old) Definition

    DTIC Science & Technology

    2010-04-21

    term failed state is very ambiguous. Noam Chomsky controversially defines failed state in such a manner that the United States is a failed state. His...28. 2 Noam Chomsky , Failed States: The Abuse of Power and the Assault on Democracy (New York: Metropolitan Books, 2006), 2. 4 state are...Center for Systemic Peace. “Polity IV Project.” http://www.systemicpeace.org/ polity/polity4.htm (accessed March 18, 2010). Chomsky , Noam

  12. Why Classroom Token Economies Fail

    ERIC Educational Resources Information Center

    Drabman, Ronald S.; Tucker, Richard D.

    1974-01-01

    The reasons for clinical failures of classroom token economies are divided into three groups: (1) Problems associated with the token program itself, (2) Problems associated with the teacher, and (3) Problems associated with the specific population on which the classroom token economy is used. Each of these problem areas is discussed. (Author)

  13. Pathophysiology of the failing heart.

    PubMed

    McElroy, P A; Shroff, S G; Weber, K T

    1989-02-01

    Cardiac (or myocardial) failure of acute onset or of chronic duration is the result of a structural and/or biochemical remodeling of the myocardium. This, in turn, compromises the contractile performance of the myocardium. The hypertrophic growth of myocytes and the architectural transformation of ventricular chamber size and shape--while initially useful compensatory responses--do not prevent the inevitable appearance of pump failure where oxygen delivery to the metabolizing tissues becomes inadequate. Indeed, the severity of cardiac failure can be judged from the level of oxygen consumption that elicits this state of impaired oxygen supply and demand. A better understanding of the mechanical behavior of the ventricular chamber, including its elastic and resistive properties, together with recent advances in our ability to measure instantaneous ventricular pressure and volume, may prove useful in identifying pathologic features of hypertrophy and dilatation in individual patients. In grading the severity of failure and comparing groups of patients, a normalization of the mechanical parameters by differences in chamber size, shape, and mass is necessary. Symptomatic cardiac failure, based invariably on inadequate oxygen delivery and/or pulmonary congestion, is more commonly the result of ventricular systolic dysfunction. Abnormalities in diastolic function, including ventricular relaxation and filling, while less common and often associated with preserved systolic pump function, do occur. Finally, it must be recognized that the failing ventricle carries an additional hydraulic load that arises from the arterial circulation to which it is coupled.(ABSTRACT TRUNCATED AT 250 WORDS)

  14. Cancer mortality in the British rubber industry.

    PubMed Central

    Parkes, H G; Veys, C A; Waterhouse, J A; Peters, A

    1982-01-01

    Although it is over 30 years since an excess of bladder cancer was first identified in British rubber workers, the fear has persisted that this hazard could still be affecting men working in the industry today. Furthermore, suspicions have also arisen that other and hitherto unsuspected excesses of cancer might be occurring. For these reasons 33 815 men, who first started work in the industry between 1 January 1946 and 31 December 1960, have been followed up to 31 December 1975 to ascertain the number of deaths attributable to malignant disease and to compare these with the expected number calculated from the published mortality rates applicable to the male population of England and Wales and Scotland. The findings confirm the absence of any excess mortality from bladder cancer among men entering the industry after 1 January 1951 (the presumed bladder carcinogens were withdrawn from production processes in July 1949), but they confirm also a statistically significant excess of both lung and stomach cancer mortality. A small excess of oesophageal cancer was also observed in both the tyre and general rubber goods manufacturing sectors. American reports of an excess of leukaemia among rubber workers receive only limited support from the present study, where a small numerical excess of deaths from leukaemia is not statistically significant. A special feature of the study is the adoption of an analytical method that permits taking into account the long latent period of induction of occupational cancer. PMID:7093147

  15. British American Tobacco’s failure in Turkey

    PubMed Central

    Lawrence, S

    2009-01-01

    Background and objectives Transnational tobacco companies (TTCs) considered Turkey an important, potential investment market because of its high consumption rates and domestic commitment to tobacco. This paper outlines how British American Tobacco (BAT) attempted to establish a joint venture with the government monopoly TEKEL, while waiting for privatisation and a private tender. Methods Analysis of tobacco industry documents from the Guildford Depository and online tobacco document sources. Results BAT failed to establish a market share in Turkey until 2000 despite repeated attempts to form a joint venture with Turkey’s tobacco monopoly, TEKEL, once the market liberalised in the mid 1980s. Conclusions BAT’s failure in the Turkish market was due to a misguided investment strategy focused solely on acquiring TEKEL and is contrasted with Philip Morris success in Turkey despite both TTCs working within Turkey’s unstable and corrupt investing climate. PMID:18845622

  16. The perilous state of seagrass in the British Isles

    PubMed Central

    Jones, Benjamin L.; Unsworth, Richard K. F.

    2016-01-01

    Seagrass ecosystems face widespread threat from reduced water quality, coastal development and poor land use. In recent decades, their distribution has declined rapidly, and in the British Isles, this loss is thought to have been extensive. Given increasing knowledge of how these ecosystems support fisheries production, the understanding of their potential rapid loss, and the difficulty in restoring them, it is vital we develop an understanding of the risks they are under, so that management actions can be developed accordingly. Developing an understanding of their environmental status and condition is therefore critical to their long-term management. This study provided, to our knowledge, the first examination of the environmental health of seagrass meadows around the British Isles. This study used a bioindicator approach and involved collecting data on seagrass density and morphology alongside analysis of leaf biochemistry. Our study provides, to the best of our knowledge, the first strong quantitative evidence that seagrass meadows of the British Isles are mostly in poor condition in comparison with global averages, with tissue nitrogen levels 75% higher than global values. Such poor status places their long-term resilience in doubt. Elemental nutrient concentrations and morphological change suggest conditions of excess nitrogen and probable low light, placing many of the meadows sampled in a perilous state, although others, situated away from human populations were perceived to be healthy. Although some sites were of a high environmental health, all sites were considered at risk from anthropogenic impacts, particularly poor water quality and boating-based disturbances. The findings of this study provide a warning of the need to take action, with respect to water quality and disturbance, to prevent the further loss and degradation of these systems across the British Isles. PMID:26909188

  17. Checklist of British and Irish Hymenoptera - Proctotrupoidea

    PubMed Central

    2016-01-01

    Abstract Background A revised checklist of the British and Irish Heloridae and Proctotrupidae (Proctotrupoidea) substantially updates the previous comprehensive checklist, dating from 1978. Country level data (i.e. occurrence in England, Scotland, Wales, Ireland and the Isle of Man) is reported where known. New information A total of three Heloridae and 39 Proctotrupidae (including only certainly recorded species) represents a 27% increase in the British list since 1978. Most species are still poorly known and there has been a dearth of taxonomic and faunistic work on the British and Irish fauna. PMID:27226750

  18. Iron Age and Anglo-Saxon genomes from East England reveal British migration history.

    PubMed

    Schiffels, Stephan; Haak, Wolfgang; Paajanen, Pirita; Llamas, Bastien; Popescu, Elizabeth; Loe, Louise; Clarke, Rachel; Lyons, Alice; Mortimer, Richard; Sayer, Duncan; Tyler-Smith, Chris; Cooper, Alan; Durbin, Richard

    2016-01-19

    British population history has been shaped by a series of immigrations, including the early Anglo-Saxon migrations after 400 CE. It remains an open question how these events affected the genetic composition of the current British population. Here, we present whole-genome sequences from 10 individuals excavated close to Cambridge in the East of England, ranging from the late Iron Age to the middle Anglo-Saxon period. By analysing shared rare variants with hundreds of modern samples from Britain and Europe, we estimate that on average the contemporary East English population derives 38% of its ancestry from Anglo-Saxon migrations. We gain further insight with a new method, rarecoal, which infers population history and identifies fine-scale genetic ancestry from rare variants. Using rarecoal we find that the Anglo-Saxon samples are closely related to modern Dutch and Danish populations, while the Iron Age samples share ancestors with multiple Northern European populations including Britain.

  19. Iron Age and Anglo-Saxon genomes from East England reveal British migration history

    PubMed Central

    Schiffels, Stephan; Haak, Wolfgang; Paajanen, Pirita; Llamas, Bastien; Popescu, Elizabeth; Loe, Louise; Clarke, Rachel; Lyons, Alice; Mortimer, Richard; Sayer, Duncan; Tyler-Smith, Chris; Cooper, Alan; Durbin, Richard

    2016-01-01

    British population history has been shaped by a series of immigrations, including the early Anglo-Saxon migrations after 400 CE. It remains an open question how these events affected the genetic composition of the current British population. Here, we present whole-genome sequences from 10 individuals excavated close to Cambridge in the East of England, ranging from the late Iron Age to the middle Anglo-Saxon period. By analysing shared rare variants with hundreds of modern samples from Britain and Europe, we estimate that on average the contemporary East English population derives 38% of its ancestry from Anglo-Saxon migrations. We gain further insight with a new method, rarecoal, which infers population history and identifies fine-scale genetic ancestry from rare variants. Using rarecoal we find that the Anglo-Saxon samples are closely related to modern Dutch and Danish populations, while the Iron Age samples share ancestors with multiple Northern European populations including Britain. PMID:26783965

  20. West Nile virus in the British Virgin Islands.

    PubMed

    Anthony, S J; Garner, M M; Palminteri, L; Navarrete-Macias, I; Sanchez-Leon, M D; Briese, T; Daszak, P; Lipkin, W I

    2014-06-01

    West Nile virus (WNV) first emerged in the US in 1999 and has since spread across the Americas. Here, we report the continued expansion of WNV to the British Virgin Islands following its emergence in a flock of free-roaming flamingos. Histologic review of a single chick revealed lesions consistent with WNV infection, subsequently confirmed with PCR, immunohistochemistry and in situ hybridization. Full genome analysis revealed 99% sequence homology to strains circulating in the US over the past decade. This study highlights the need for rapid necropsy of wild bird carcasses to fully understand the impact of WNV on wild populations.

  1. Racial Discrimination in the British Labor Market.

    ERIC Educational Resources Information Center

    Firth, Michael

    1981-01-01

    Contains results of a study of racial discrimination in the British job market for accountants and financial executives. Results show that considerable discrimination remains several years after the adoption of the Race Relations Act of 1968. (CT)

  2. British and American attitudes toward credit cards.

    PubMed

    Yang, Bijou; James, Simon; Lester, David

    2006-04-01

    American university students owned more than twice as many credit cards as British university students. However, scores on a credit card attitude scale predicted the number of cards owned by respondents in both countries.

  3. Libraries in British Columbia: MedlinePlus

    MedlinePlus

    ... this page: https://medlineplus.gov/libraries/britishcolumbia.html Libraries in British Columbia To use the sharing features ... George University Hospital of Northern BC Northern Health Library Services / ILL Learning & Development Centre 1475 Edmonton Street ...

  4. Going coastal: Shared evolutionary history between coastal British Columbia and Southeast Alaska wolves (canis lupus)

    USGS Publications Warehouse

    Weckworth, B.V.; Dawson, N.G.; Talbot, S.L.; Flamme, M.J.; Cook, J.A.

    2011-01-01

    Background: Many coastal species occupying the temperate rainforests of the Pacific Northwest in North America comprise endemic populations genetically and ecologically distinct from interior continental conspecifics. Morphological variation previously identified among wolf populations resulted in recognition of multiple subspecies of wolves in the Pacific Northwest. Recently, separate genetic studies have identified diverged populations of wolves in coastal British Columbia and coastal Southeast Alaska, providing support for hypotheses of distinct coastal subspecies. These two regions are geographically and ecologically contiguous, however, there is no comprehensive analysis across all wolf populations in this coastal rainforest. Methodology/Principal Findings: By combining mitochondrial DNA datasets from throughout the Pacific Northwest, we examined the genetic relationship between coastal British Columbia and Southeast Alaska wolf populations and compared them with adjacent continental populations. Phylogenetic analysis indicates complete overlap in the genetic diversity of coastal British Columbia and Southeast Alaska wolves, but these populations are distinct from interior continental wolves. Analyses of molecular variation support the separation of all coastal wolves in a group divergent from continental populations, as predicted based on hypothesized subspecies designations. Two novel haplotypes also were uncovered in a newly assayed continental population of interior Alaska wolves. Conclusions/Significance: We found evidence that coastal wolves endemic to these temperate rainforests are diverged from neighbouring, interior continental wolves; a finding that necessitates new international strategies associated with the management of this species. ?? 2011 This is an open-access article.

  5. Certified mail fails to reach an Emergency Department population.

    PubMed

    Thompson, James R; Stephens, Sheila; Summers, Richard L

    2004-11-01

    The objective of this study was to determine if correspondence sent by regular mail would be delivered more often than correspondence sent by certified mail. Correspondence was prospectively randomized and mailed by United States Postal Service using either regular mail service or certified mail service. Mailings were analyzed based on patient demographic information, whether or not mail was returned, and the reason for the return. Certified mail was sent to 145 patients; 58 (40%) of the mailings were returned. Wrong addresses accounted for only 23 (16%) of these, whereas the addressee never claimed 35 (24%). Regular mail was sent to 126 patients, and 19 (15%) of the letters were returned. Wrong addresses accounted for 18 (14%) of these letters, and only 1 (1%) was refused for delivery. In conclusion, when compared with certified mail, regular mail is a more effective means of reaching patients with follow-up information after an Emergency Department visit.

  6. Failed supernovae explain the compact remnant mass function

    SciTech Connect

    Kochanek, C. S.

    2014-04-10

    One explanation for the absence of higher mass red supergiants (16.5 M {sub ☉} ≲ M ≲ 25 M {sub ☉}) as the progenitors of Type IIP supernovae (SNe) is that they die in failed SNe creating black holes. Simulations show that such failed SNe still eject their hydrogen envelopes in a weak transient, leaving a black hole with the mass of the star's helium core (5-8 M {sub ☉}). Here we show that this naturally explains the typical masses of observed black holes and the gap between neutron star and black hole masses without any fine-tuning of stellar mass loss, binary mass transfer, or the SN mechanism, beyond having it fail in a mass range where many progenitor models have density structures that make the explosions more likely to fail. There is no difficulty including this ∼20% population of failed SNe in any accounting of SN types over the progenitor mass function. And, other than patience, there is no observational barrier to either detecting these black hole formation events or limiting their rates to be well below this prediction.

  7. The Measurement and Evaluation of Social Attitudes in Two British Cohort Studies

    ERIC Educational Resources Information Center

    Cheng, Helen; Bynner, John; Wiggins, Richard; Schoon, Ingrid

    2012-01-01

    This paper presents an empirical evaluation of the internal consistency and validity of six attitudes scales assessing left-right beliefs, political cynicism, antiracism, libertarian-authoritarian views, and gender equality (two versions) in two large nationally representative samples of the British population born in 1958 and 1970. In the 1958…

  8. The Recruitment of International Students: The British Experience, 1979-1987 and the Way Forward.

    ERIC Educational Resources Information Center

    Belcher, John

    1987-01-01

    A discussion of recent British experiences and policy concerning the recruitment of foreign students looks at a 1979 policy decision about international student fees, institutional response, overseas marketing efforts, and the resulting foreign student population and its problems, and proposes directions for institutions, public agencies, and…

  9. State and Church in British Honduran Education, 1931-39: A British Colonial Perspective.

    ERIC Educational Resources Information Center

    Hitchen, Peter

    2000-01-01

    Offers an analysis of church and state influences on the development of education in British Honduras (now Belize). Focuses on the British neglect of education in the colony; the emergence of tensions between the church and state, exploring issues related to Roman Catholic and Protestant rivalry; and church-state issues. (CMK)

  10. Hollow Threats: Why Coercive Diplomacy Fails

    DTIC Science & Technology

    2015-06-01

    Most likely, Argentina invaded the Falkland Islands in an attempt to achieve that unity and overcome its affliction of domestic discord. The...benefit during British coercion of Argentina was this hoped-for internal unity. 26. George, “Coercive Diplomacy,” 77. 27. Barry R. Posen, “Military...recognized government has taken refuge in Eastern Libya.90 In December 2014, one of the larger militias, Fajr Libya, fought to control oil export

  11. Impact of changes in the IOC-MC asthma criteria: a British perspective

    PubMed Central

    Dickinson, J; Whyte, G; McConnell, A; Harries, M

    2005-01-01

    Background: Since 2001 the International Olympic Committee-Medical Commission (IOC-MC) has required athletes using inhaled ß2 agonists to provide clinical evidence of their asthmatic condition. The aim of this study was to compare the reported prevalence of asthma at the 2000 and 2004 Olympic Games in the Great British Olympic team (Team GB). Methods: Following local ethics committee approval, 271 athletes (165 men) from the 2004 Team GB volunteered and provided written informed consent. An athlete was confirmed asthmatic if he or she had a positive bronchoprovocation or bronchodilator test as defined by the IOC-MC. Pre-Olympic medical forms from the 2000 Team GB were also examined to establish the prevalence of asthma among the members of Team GB at the 2000 Olympic Games. Results: The prevalence of asthma in the two teams at the 2000 and 2004 Olympic Games was similar (21.2% and 20.7%, respectively). In the 2004 Olympic Games 13 of 62 athletes (21.0%) with a previous diagnosis of asthma tested negative. A further seven with no previous diagnosis of asthma tested positive. Conclusions: The prevalence of asthma within Team GB remained unchanged between 2000 and 2004. The IOC-MC requirement that asthmatic athletes must submit documented evidence of asthma has highlighted that 13 (21.0%) previously diagnosed as asthmatic failed to demonstrate evidence of asthma while seven athletes with no previous history or diagnosis of asthma tested positive. Screening for asthma within elite athletic populations using bronchoprovocation challenges appears warranted to assist athletes in preparing more effectively for major sporting events. PMID:16061702

  12. The Post-War British "Re-Education" Policy for German Universities and Its Application at the Universities of Göttingen and Cologne (1945-1947)

    ERIC Educational Resources Information Center

    Euros, Glesni

    2016-01-01

    The crux of British aims for Germany following the Second World War focused on "re-education" and democratisation. Well aware that the victors' policies following World War One had failed to prevent Germany from pursuing an expansionist path once again, the plan was to help Germany learn from her problematic past. These aims extended to…

  13. A Follow-Up Study of Career/Technical Students from the British Columbia Community Colleges and Institutes: Summary Report. Report No. 5-04-857.

    ERIC Educational Resources Information Center

    Dennison, John D.; And Others

    In Fall 1980, a follow-up survey was conducted of students who had graduated, withdrawn from or otherwise left career/technical programs at British Columbia's 14 community colleges and institute of technology. The study sought to determine: (1) why students undertook career/technical programs; (2) if and for what reasons students failed to…

  14. Revisiting Fisher: range size drives the correlation between variability and abundance of British bird eggs.

    PubMed

    Lapiedra, O; Price, T D

    2015-06-01

    We evaluate the correlation between intraspecific variation in egg size and population size in breeding British birds. Using information on abundance, range occupancy, migration status and phylogenetic relationships among species, we show that a wider geographical distribution rather than larger population size per se best predicts egg size variability. A similar result applies to wing length variability. Results from a phylogenetic path analysis suggest that geographical variation is the most parsimonious causal explanation for high intraspecific variation in common species.

  15. Cultural and age differences in beliefs about depression: British Bangladeshis vs. British Whites

    PubMed Central

    McClelland, Alastair; Khanam, Shopnara; Furnham, Adrian

    2013-01-01

    This study examines beliefs about depression as a function of ethnic background (British Bangladeshis vs. British Whites) and age. A total of 364 participants completed a 65-item questionnaire, containing general questions regarding depression and anti-depressive behaviour; the causes of depression, and treatments for depression. The hypotheses were broadly supported; there were significant interactions between ethnicity and age, which generally revealed an increasingly negative attitude towards depression with increasing age amongst British Bangladeshis. Older British Bangladeshis believed depression was an illness that brought a sense of shame and loss of dignity to the individual and his or her family, and they also favoured a lay referral system for sufferers. They also had more superstitious beliefs about depression than both younger British Bangladeshis and British Whites. A pattern of increasing negativity with increasing age was not evident amongst the British Whites, but older individuals in both groups tended to believe that depression was not helped by psychological intervention. The attitudes towards depression in the young was similar (and generally positive) in both ethnic groups. These findings highlight the necessity to provide more culturally sensitive and accessible services for migrant communities – particularly amongst older individuals. PMID:25076835

  16. Myocardial regeneration of the failing heart.

    PubMed

    Akhmedov, Alexander T; Marín-García, José

    2013-11-01

    Human heart failure (HF) is one of the leading causes of morbidity and mortality worldwide. Currently, heart transplantation and implantation of mechanical devices represent the only available treatments for advanced HF. Two alternative strategies have emerged to treat patients with HF. One approach relies on transplantation of exogenous stem cells (SCs) of non-cardiac or cardiac origin to induce cardiac regeneration and improve ventricular function. Another complementary strategy relies on stimulation of the endogenous regenerative capacity of uninjured cardiac progenitor cells to rebuild cardiac muscle and restore ventricular function. Various SC types and delivery strategies have been examined in the experimental and clinical settings; however, neither the ideal cell type nor the cell delivery method for cardiac cell therapy has yet emerged. Although the use of bone marrow (BM)-derived cells, most frequently exploited in clinical trials, appears to be safe, the results are controversial. Two recent randomized trials have failed to document any beneficial effects of intracardiac delivery of autologous BM mononuclear cells on cardiac function of patients with HF. The remarkable discovery that various populations of cardiac progenitor cells (CPCs) are present in the adult human heart and that it possesses limited regeneration capacity has opened a new era in cardiac repair. Importantly, unlike BM-derived SCs, autologous CPCs from myocardial biopsies cultured and subsequently delivered by coronary injection to patients have given positive results. Although these data are promising, a better understanding of how to control proliferation and differentiation of CPCs, to enhance their recruitment and survival, is required before CPCs become clinically applicable therapeutics.

  17. Checklist of British and Irish Hymenoptera - Ichneumonidae

    PubMed Central

    2016-01-01

    Abstract Background The checklist of British and Irish Ichneumonidae is revised, based in large part on the collections of the Natural History Museum, London and the National Museums of Scotland, Edinburgh. Distribution records are provided at the country level. New information Of the 2,447 species regarded as valid and certainly identified, 214 are here recorded for the first time from the British Isles. Neorhacodinae is considered to be a separate subfamily rather than a synonym of Tersilochinae. Echthrini is treated as a junior synonym of the tribe Cryptini, not Hemigastrini. Echthrus Gravenhorst and Helcostizus Förster are classified in Cryptini rather than, respectively, Hemigastrini and Phygadeuontini. PMID:27733812

  18. Checklist of British and Irish Hymenoptera - Braconidae

    PubMed Central

    Shaw, Mark R.; Godfray, H. Charles J.

    2016-01-01

    Abstract Background The checklist of British and Irish Braconidae is revised, based in large part on the collections of the National Museums of Scotland, Edinburgh, and the Natural History Museum, London. Distribution records are provided at the country level together with extensive synonymy and bibliography. New information Of the 1,338 species regarded as valid, presumed native and certainly identified, 83 are here recorded for the first time from the British Isles. One new synonym is established (Dyscritus suffolciensis Morley, 1933 = Syntretus splendidus (Marshall, 1887) syn. nov.) PMID:27226759

  19. US SNUPPS design modified for British use

    SciTech Connect

    Not Available

    1982-11-01

    Britain is making some modifications in the Westinghouse pressurized water reactor (PWR) generic design used in the US and complying with the Standardized Nuclear Utility Power Plant System (SNUPPS). Britain is also working closely with Bechtel personnel on construction and safety improvements. The safety changes will improve emergency-core-cooling-system reliability, reduce the number of welds, improve shutdown capability, provide an emergency ultimate heat sink, lower staff radiation exposure, use turbine-generator configurations that are standard in British power plants, adapt to the British grid frequencies, and strengthen secondary containment buildings. 1 figure. (DCK)

  20. Super-Earths as Failed Cores in Orbital Migration Traps

    NASA Astrophysics Data System (ADS)

    Hasegawa, Yasuhiro

    2016-11-01

    I explore whether close-in super-Earths were formed as rocky bodies that failed to grow fast enough to become the cores of gas giants before the natal protostellar disk dispersed. I model the failed cores’ inward orbital migration in the low-mass or type I regime to stopping points at distances where the tidal interaction with the protostellar disk applies zero net torque. The three kinds of migration traps considered are those due to the dead zone's outer edge, the ice line, and the transition from accretion to starlight as the disk's main heat source. As the disk disperses, the traps move toward final positions near or just outside 1 au. Planets at this location exceeding about 3 M ⊕ open a gap, decouple from their host traps, and migrate inward in the high-mass or type II regime to reach the vicinity of the star. I synthesize the population of planets that formed in this scenario, finding that a fraction of the observed super-Earths could have been failed cores. Most super-Earths that formed this way have more than 4 M ⊕, so their orbits when the disks dispersed were governed by type II migration. These planets have solid cores surrounded by gaseous envelopes. Their subsequent photoevaporative mass loss is most effective for masses originally below about 6 M ⊕. The failed core scenario suggests a division of the observed super-Earth mass-radius diagram into five zones according to the inferred formation history.

  1. British International Schools: The Deployment and Training of Teaching Assistants

    ERIC Educational Resources Information Center

    Tarry, Estelle

    2011-01-01

    This article reports on research carried out on behalf of the Council of British International Schools (COBIS) as to the role and deployment of British international school teaching assistants. Through questionnaires and a follow up open discussion with headteachers from British international schools it was found that, due to the differing…

  2. A Firsthand Look at the British Open School.

    ERIC Educational Resources Information Center

    Staley, Gerald J.

    The author of this informal critique of the British Open School spent the 1972-73 academic year as a teacher in London's Battersea School as part of an exchange program in which six British open school teachers exchanged places with six teachers from British Columbia, Canada. After a brief description of the daily and weekly program at Battersea…

  3. Prevalence of problematic mobile phone use in British adolescents.

    PubMed

    Lopez-Fernandez, Olatz; Honrubia-Serrano, Luisa; Freixa-Blanxart, Montserrat; Gibson, Will

    2014-02-01

    The problematic use of mobile phones among adolescents has not been widely studied. There are very few instruments for assessing potential technological addiction to mobile phones, or for categorizing different types of users or uses. The most widely used scale is the Mobile Phone Problem Use Scale (MPPUS), which is used to study adult populations, and has been applied in various forms in international contexts. The aims of this study were to adapt the Spanish version of this scale (MPPUSA) to British adolescents, and then to estimate the prevalence of possible problematic users. A questionnaire was administered to a sample of 1,529 secondary school pupils aged between 11 and 18 years, with 1,026 completed questionnaires being collected. The analysis showed that the factor and construct validity and reliability were comparable to those obtained in previous studies. The prevalence of problematic users among the students was 10%, and the typical problematic user tended to be an adolescent between 11 and 14 years old, studying in a public school, who considered themselves to be an expert user of this technology, who made extensive use of his/her mobile phone, and who attributed the same problem of use among their peers. These users presented notable scores in all the symptoms covered by the scale used to assess problematic use. In conclusion, the adaptation of the MPPUSA as a screening scale for British adolescents presents good sensitivity and specificity for detecting the main addictive symptoms proposed in this validated version.

  4. A decade of experience: Cryptococcus gattii in British Columbia.

    PubMed

    Bartlett, Karen H; Cheng, Po-Yan; Duncan, Colleen; Galanis, Eleni; Hoang, Linda; Kidd, Sarah; Lee, Min-Kuang; Lester, Sally; MacDougall, Laura; Mak, Sunny; Morshed, Muhammad; Taylor, Marsha; Kronstad, James

    2012-06-01

    It has been over a decade since Cryptococcus gattii was first recognized as the causative organism of an outbreak of cryptococcosis on Vancouver Island, British Columbia. A number of novel observations have been associated with the study of this emergent pathogen. A novel genotype of C. gattii, VGIIa was described as the major genotype associated with clinical disease. Minor genotypes, VGIIb and VGI, are also responsible for disease in British Columbians, in both human and animal populations. The clinical major genotype VGIIa and minor genotype VGIIb are identical to C. gattii isolated from the environment of Vancouver Island. There is more heterogeneity in VGI, and a clear association with the environment is not apparent. Between 1999 and 2010, there have been 281 cases of C. gattii cryptococcosis. Risk factors for infection are reported to be age greater than 50 years, history of smoking, corticosteroid use, HIV infection, and history of cancer or chronic lung disease. The major C. gattii genotype VGIIa is as virulent in mice as the model Cryptococcus, H99 C. neoformans, although the outbreak strain produces a less protective inflammatory response in C57BL/6 mice. The minor genotype VGIIb is significantly less virulent in mouse models. Cryptococcus gattii is found associated with native trees and soil on Vancouver Island. Transiently positive isolations have been made from air and water. An ecological niche for this organism is associated within a limited biogeoclimatic zone characterized by daily average winter temperatures above freezing.

  5. Draining the Swamp: The British Strategy of Population Control

    DTIC Science & Technology

    2006-01-01

    so, these tactics broke the Mau Mau. With independence, power passed peacefully to Jomo Kenyatta . While Kenyatta had been falsely impris- oned for... Kenyatta in 1954 instead of imprisoning him. 24. George C. Herring, America’s Longest War: The United States and Vietnam, 1950-1975 (3d ed.; New York

  6. British Library Conducts New Technology Research.

    ERIC Educational Resources Information Center

    Graddon, Pamela H. B.

    1982-01-01

    Discusses technological research efforts by the Research and Development Department of the British Library in the areas of videotex, videodisc, and teleconferencing, noting the videotex service known as Prestel and the department's network project, called BLEND (Birmingham and Loughborough Electronic Network Development). (EJS)

  7. A History of Modern British Adult Education.

    ERIC Educational Resources Information Center

    Fieldhouse, Roger

    The purpose of this book is: to set the historical development of British adult education in its wider policy and ideological context; to examine its various forms and formulations; and to identify what purpose or purposes it has served. The 16 chapters are as follows: "Historical and Political Context" (Roger Fieldhouse); "The…

  8. Drivers of Cousin Marriage among British Pakistanis

    PubMed Central

    Shaw, Alison

    2014-01-01

    Background/Aim Why has the apparently high rate of cousin marriage among Bradford Pakistanis been sustained, 50 years since Pakistani migration to Britain began? Methods A review of the anthropological literature on Pakistani migration and settlement, British Pakistani marriage patterns and the phenomenon of transnational marriage. Results British Pakistanis are diverse in regional origins and social class characteristics, with many Bradford Pakistanis originating from the Mirpur district and northern Punjab. British Pakistani marriages often involve a partner from Pakistan who joins a spouse in the UK. Transnational marriage of first cousins offers relatives in Pakistan opportunities for a ‘better’ life in the West and are important for British Pakistanis for economic, social, cultural and emotional reasons. These processes are also differentially influenced by region of origin and class characteristics in Pakistan as well as by education, employment and locality in Britain. The pattern observed in Bradford may not be applicable nationally. Conclusion Further research examining marital decisions over several generations in families differing by social class, region of origin in Pakistan and locality in Britain is necessary to contextualise the findings from Bradford. PMID:25060267

  9. British used Congreve Rockets to Attack Napoleon

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Sir William Congreve developed a rocket with a range of about 9,000 feet. The incendiary rocket used black powder, an iron case, and a 16-foot guide stick. In 1806, British used Congreve rockets to attack Napoleon's headquarters in France. In 1807, Congreve directed a rocket attack against Copenhagen.

  10. Reading Habits of British Secondary Students.

    ERIC Educational Resources Information Center

    Newkirk, Thomas

    Findings from a number of studies of the reading interests and habits of British secondary school students are reviewed, and the results of a new survey of the opinions of 55 teachers are briefly reported. The studies indicate that a number of "classic" texts are popular but that "subliterature" is also popular and becomes more…

  11. British School Chemistry Laboratories, 1830-1920.

    PubMed

    Brock, W H

    2017-04-05

    The essay examines the British secondary school as a chemical site in the nineteenth century up until the 1920s. It sketches how chemistry became part of the secondary school curriculum in the mid-nineteenth century, discusses how school laboratories were designed, and examines to what extent school laboratories provided opportunities for original research by schoolmasters.

  12. Considerations for Education Reform in British Columbia

    ERIC Educational Resources Information Center

    Santos, Ana

    2012-01-01

    Countries around the world refer to twenty-first century education as essential to maintaining personal and national economic advantage and draw on this discourse to advocate for and embark on educational reform. This paper examines issues around education reform, particularly in British Columbia. It argues that reformers should give careful…

  13. Did Senior British Officers Effectively Lead Change?

    DTIC Science & Technology

    2014-12-12

    additional information. To obtain greater fidelity and detail on the changes undergone by the British Army, a set of broader follow-up questions were set...were analyzed against the quantitative data findings as well as the Rainey and Fernandez model. These were used to gather detail and fidelity to...

  14. The British Council's Global Cataloguing Service.

    ERIC Educational Resources Information Center

    Magalhaes, Rodrigo; Nogueira, Madalena Sa

    1985-01-01

    The British Council Global Cataloging Service was initiated in 1980 to reduce duplication of cataloging same titles in council libraries abroad. Each of 56 council libraries participating in system receives list of new accessions and updated microfiche catalog. Portugal was one of the first six countries chosen to test the system. (EJS)

  15. British Columbia/Alberta Transfer System Protocol

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2007

    2007-01-01

    The purpose of this agreement is to provide assurance to students that they will receive transfer credit for courses or programs they have successfully completed where the content/outcomes are demonstrably equivalent to those offered at the institution to which they transfer. This protocol is undertaken by the British Columbia Council on…

  16. The British Novel: Conrad to the Present.

    ERIC Educational Resources Information Center

    Wiley, Paul L.

    Intended for advanced undergraduate and graduate students who desire a useful research tool, this bibliography cites the works of and about British novelists, beginning with Joseph Conrad and terminating in 1950. The listings are selective with proper emphasis given to less celebrated but distinctive writers. A preface explaining the numerous…

  17. British Columbia. Reference Series No. 25.

    ERIC Educational Resources Information Center

    Department of External Affairs, Ottawa (Ontario).

    This booklet, one of a series featuring the Canadian provinces, presents a brief overview of British Columbia and is suitable for teacher reference or student reading. A discussion of the province's history includes the early European explorers, Indian natives, and later fur traders and settlers. The building of the transcontinental railway, entry…

  18. First Employment of British Pharmacology Graduates

    ERIC Educational Resources Information Center

    Hollingsworth, Michael; Markham, Anthony

    2006-01-01

    A survey was conducted in UK Universities to identify the employment of pharmacology graduates (BSc, MSc and PhD) 6 months after graduation in 2003. The aim was to provide data for the British Pharmacological Society (BPS) so they could offer advice to interested bodies and to University staff for careers information. 85% of 52 Universities…

  19. Earnings Returns to the British Education Expansion

    ERIC Educational Resources Information Center

    Devereux, Paul J.; Fan, Wen

    2011-01-01

    We study the effects of the large expansion in British educational attainment that took place for cohorts born between 1970 and 1975. Using the Quarterly Labour Force Survey, we find that the expansion caused men to increase education by about a year on average and gain about 8% higher wages; women obtained a slightly greater increase in education…

  20. Deprivatizing Private Education: The British Columbia Experience.

    ERIC Educational Resources Information Center

    Barman, Jean

    1991-01-01

    The experience of British Columbia in deprivatizing private schools by requiring their registration and providing financial support is reviewed. It is argued that family choice and state control have grown dialectically. Government funding has created higher enrollments and new schools, but resultant public oversight ultimately constrains choice.…

  1. Martin Trow on British Higher Education

    ERIC Educational Resources Information Center

    Silver, Harold

    2009-01-01

    For almost half a century from the early 1960s Martin Trow was the most persistent American commentator on British higher education. He analysed the main reports from Robbins to Dearing, developed and applied a language for discussing common problems amongst different systems, and focused on the uncertain progress of the UK to mass higher…

  2. British Chinese Children: Agency and Action

    ERIC Educational Resources Information Center

    Clayton, Carmen Lau

    2013-01-01

    The assumption that Chinese young people are passive beings with little or no agency is a dominant theme within the academic literature. However PhD research findings demonstrate how British Chinese adolescents (aged 11-14) do exhibit varying degrees of agency in their lives. Here, agency is understood as individuals having the capacity to act, to…

  3. Home Data Banks Turn British On

    ERIC Educational Resources Information Center

    Science News, 1978

    1978-01-01

    Describes the operation and numerous capabilities of a British computerized data retrieval system named Prestel. It provides access, through the regular telephone network and a TV screen, to computer-based information supplied by many companies, agencies and commercial outlets. (GA)

  4. British Writers; Modules for Teacher Corps.

    ERIC Educational Resources Information Center

    Gilliard, Fred

    This booklet, containing eight instructional modules on works by major British writers, can be used either within a lower-level literature course for non-English majors or in a survey course for English majors. The first four modules focus on works from the early English period through the Elizabethan Age: "Beowulf,""Sir Gawain and the Green…

  5. Live from Westminster: Broadcasting the British Parliament.

    ERIC Educational Resources Information Center

    Scott, Peter Hardiman

    1978-01-01

    Describes live radio broadcasting from the chambers of the British Parliament. After 55 years of campaigning by broadcasters and Members of Parliament, and following experimental broadcasting by the BBC and Independent Local Radio, service was installed in April 1978. Initial experimentation, current procedures, and implications for television…

  6. The British Southern Campaign 1778-1781: The Impact of Strategic Level Assessments and Assumptions on British Decision Making

    DTIC Science & Technology

    2010-05-03

    Georgi ~ and the Carolinas against the British, driving Campbell (the British commander) out of the backcountry." 31 Few Georgians joined the British...64 Wilson, 30-35. 65 Ibid, 101-102. 66 Shy, 296. 67 Wilson, 63-64. 29 68 Smith, 98. 30 Bibliography Babits, Lawrence E. and Joshua Howard

  7. A serach for 'failed clusters' of galaxies

    NASA Technical Reports Server (NTRS)

    Tucker, W. H.; Tananbaum, H.; Remillard, R. A.

    1995-01-01

    We describe a search for a new type of object - large clouds of hot gas with no visible galaxies - which we call failed clusters of galaxies. We calculate the expected X-ray luminosity, temperature, and angular diameter of such objects as a function of total cloud mass and convert the results to expected X-ray fluxes from failed clusters at different redshifts. Using the Einstein Imaging Proportional Counter (IPC) database, we establish a strategy to search for candidate failed clusters. From this initial screening of 1435 IPC fields, 17 candidates are selected for more detailed analysis, which indicates that 10 of these are very probably extended X-ray sources. Optical follow-up on the 10 prime candidates finds eight clusters of galaxies (including six reproted for the first time in this paper), one stellar identification, and one without an obvious optical counterpart (the candidate with the weakest evidence for X-ray extent). Investigation of several candidates with less evidence for X-ray extent yields two additional new clusters of galaxies. A conservative comparison of our results with the Einstein Extended Medium Sensitivity Survey demonstrates that failed clusters are a relatively unimportant contributor to the mass density of the universe. Our inability to find failed clusters is consistent with the hierarchical clustering scenario for the formation of galaxies and clusters.

  8. Lunacy and the 'Islands in the British Seas'.

    PubMed

    Hirst, David

    2007-12-01

    In the mid-nineteenth century the Dependent Territories of Jersey, Guernsey and the Isle of Man all had small, relatively stable populations, many of whom did not speak English as their first language. The response of each to the public asylum movement was very different. Guernsey had an asylum by 1852, but Jersey and the Isle of Man opened permanent asylums only in 1868. This comparative study examines the interactions between British government agencies, the Home Office, Commissioners in Lunacy and Lieutenant Governors, and the autonomous insular legislatures. It discusses the reasons why Jersey and the Isle of Man were reluctant to establish publicly funded asylums, the alternatives considered, and the opportunities afforded to private madhouse proprietors by absent or lax supervisory frameworks.

  9. Diffuse neutrino flux from failed supernovae.

    PubMed

    Lunardini, Cecilia

    2009-06-12

    I study the diffuse flux of electron antineutrinos from stellar collapses with direct black hole formation (failed supernovae). This flux is more energetic than that from successful supernovae, and therefore it might contribute substantially to the total diffuse flux above realistic detection thresholds. The total flux might be considerably higher than previously thought, and approach the sensitivity of Super-Kamiokande. For more conservative values of the parameters, the flux from failed supernovae dominates for antineutrino energies above 30-45 MeV, with potential to give an observable spectral distortion at megaton detectors.

  10. Predisposing factors leading to depression in the British Army.

    PubMed

    Finnegan, Alan; Finnegan, Sara; McGee, Paula; Srinivasan, Mike; Simpson, Robin

    Few studies have explored the predisposing factors leading to depression within the British Army, and this qualitative investigation provides a novel approach to advance knowledge in this poorly researched area. Information was provided by army mental health (MH) clinicians, with results aligned to theoretical groupings under the headings of: occupational stressors; macho culture, stigma and bullying; unhappy young soldier; relationships and gender. These issues were influenced by peacetime and operational settings; the support offered by the Army Medical Services and unit command. The results indicate that Army personnel are exposed to multi-factorial stressors that are incremental/accumulative in nature. Soldiers can cope with extreme pressures, often in hostile environments, but often cannot cope with a failing relationship. Officers were worried about the occupational implications of reporting ill, and the negative impact on their career, and might seek support from private civilian agencies, which have potentially dangerous ramifications as they may still deploy. GPs refer female soldiers more frequently for a mental health assessment because women express their emotions more openly then men. Young disillusioned soldiers who want to leave the Army form the main group of personnel accessing mental health support, although often they are not clinically depressed.

  11. Failing to protect humanitarian workers: lessons from Britain and Voluntary Aid Detachments in the Second World War.

    PubMed

    Verma, Amol A

    2017-03-19

    This paper draws on official records of international and British organizations, newspaper reports, and volunteer memoirs to study the failure to protect humanitarian workers in the Second World War. The Second World War saw a significant expansion in the use of air warfare and flying missiles and these technological advances posed a grave threat to civilians and humanitarian workers. In this context, the International Committee of the Red Cross advocated unsuccessfully to restrict air warfare and create safe hospital zones. The British Government grappled with the tension between military and humanitarian objectives in setting its bombardment policy. Ultimately, humanitarian principles were neglected in pursuit of strategic aims, which endangered civilians and left humanitarian workers particularly vulnerable. British Voluntary Aid Detachment nurses experienced more than six-fold greater fatality rates than civil defence workers and the general population. The lessons from failures to protect humanitarian workers in the face of evolutions in warfare remain profoundly relevant.

  12. Rodenticides in British barn owls.

    PubMed

    Newton, I; Wyllie, I; Freestone, P

    1990-01-01

    effect on Barn Owl populations in Britain, further monitoring of residue levels and population trends in desirable.

  13. Truffle diversity (Tuber, Tuberaceae) in British Columbia.

    PubMed

    Berch, Shannon M; Bonito, Gregory

    2016-08-01

    To improve baseline data for the developing truffle industry in British Columbia, we compiled existing Tuber species sequences from published and unpublished studies and generated new ITS sequences for truffles belonging to Tuber collected in the province. In doing so, we obtained evidence that 13 species of Tuber occur in the province, including six introduced and seven native species, two of which are putative undescribed species. Of the native species, the Tuber anniae species complex is widely distributed in the province while Tuber beyerlei appears to be much more restricted in distribution. Four of the introduced species have commercial value (Tuber melanosporum, Tuber aestivum, Tuber brumale, and Tuber borchii) as do two of the native species (Tuber gibbosum and Tuber oregonense). Focused sampling on likely tree hosts, both hardwood and Pinaceae species, as well as in currently unexplored parts of the province seems likely to expand our knowledge of the diversity and distribution of Tuber species in British Columbia.

  14. Flood Hazard Management: British and International Perspectives

    NASA Astrophysics Data System (ADS)

    James, L. Douglas

    This proceedings of an international workshop at the Flood Hazard Research Centre (Queensway, Enfield, Middlesex, U.K.) begins by noting how past British research on flood problems concentrated on refining techniques to implement established policy. In contrast, research covered in North American and Australian publications involved normative issues on policy alternatives and administrative implementation. The workshop's participants included 16 widely recognized scientists, whose origins were about equally divided between Britain and overseas; from this group the workshop's organizers expertly drew ideas for refining British urban riverine flood hazard management and for cultivating links among researchers everywhere. Such intellectual exchange should be of keen interest to flood hazard program managers around the world, to students of comparative institutional performance, to those who make policy on protecting people from hazards, and to hydrologists and other geophysicists who must communicate descriptive information for bureaucratic, political, and public decision- making.

  15. Trace nutrients. Selenium in British food.

    PubMed

    Thorn, J; Robertson, J; Buss, D H; Bunton, N G

    1978-03-01

    1. The amount of selenium in nationally representative samples of prepared and cooked groups of foods, and in a variety of raw individual foods, was determined fluorimetrically. 2. The average British diet was calculated to provide approximately 60 microgram Se/d, of which half was derived from cereals and cereal products and another 40% from meat and fish. Milk, table fats, fruit and vegetables provided little or no Se. 3. Individual foods which were particularly rich in Se (greater than 0.2 mg/kg) included 'bread-making' and wholemeal flours, kidney, fatty fish, brazil nuts (Bertholletia excelsa) and several other varieties of nut. In contrast, breast milk and other foods for babies (except some cereal products) contained little Se. 4. The total intake, and the amounts of Se in major foods, were lower than in most other studies. This is probably the result of the comparatively low levels of this element in British soil.

  16. Health status and the development of health services in colonial state: the case of British Malaya.

    PubMed

    Leng, C H

    1982-01-01

    The health of a population and the development of health services in a country at a particular time in history are directly linked to the socioeconomic system. This paper discusses health and health services in Malay Peninsula during the time that it was a British colony. Economic production under British colonialism, which is basically a capitalist system, is organized primarily for the purpose of realizing profits. The health of the population is in direct conflict with and generally subordinated to this main objective. The pattern of health that emerges reflects this general framework. Moreover, health services under the colonialist system are developed primarily to serve the economic interests of the colonialists. Hence, the structure of health services is biased toward curative medicine and centered mainly in the urban areas.

  17. Sequence variation at the phenylalanine hydroxylase gene in the British Isles.

    PubMed Central

    Tyfield, L A; Stephenson, A; Cockburn, F; Harvie, A; Bidwell, J L; Wood, N A; Pilz, D T; Harper, P; Smith, I

    1997-01-01

    Using mutation and haplotype analysis, we have examined the phenylalanine hydroxylase gene in the phenylketonuria populations of four geographical areas of the British Isles: the west of Scotland, southern Wales, and southwestern and southeastern England. The enormous genetic diversity of this locus within the British Isles is demonstrated in the large number of different mutations characterized and in the variety of genetic backgrounds on which individual mutations are found. Allele frequencies of the more common mutations exhibited significant nonrandom distribution in a north/south differentiation. Differences between the west of Scotland and southwestern England may be related to different events in the recent and past histories of their respective populations. Similarities between southern Wales and southeastern England are likely to reflect the heterogeneity that is seen in and around two large capital cities. Finally, comparison with more recently colonized areas of the world corroborates the genealogical origin by range expansion of several mutations. PMID:9012412

  18. The Royal Navy and British Security Policy.

    DTIC Science & Technology

    1983-12-01

    SCHOOL December 1983 Author Approved by: Tesis Avisor s" econd R e r Chafrman, Department of National Security Affairs -- and Policy Sciences " Dean of...8217s based on the 14 VULCAN , VICTOR and VALIANT bombers. Although cooperation with the American SAC was envisioned from the begining, the force did...British strategic nuclear deterrent. This responsibility was once the domain of the Royal Air Force and its VULCAN , VICTOR, and VALIANT bombers, but after

  19. Checklist of British and Irish Hymenoptera - Cynipoidea

    PubMed Central

    Forshage, Mattias; Bowdrey, Jeremy; Spooner, Brian M.; van Veen, Frank

    2017-01-01

    Abstract Background The British and Irish checklist of Cynipoidea is revised, considerably updating the last complete checklist published in 1978. Disregarding uncertain identifications, 220 species are now known from Britain and Ireland, comprising 91 Cynipidae (including two established non-natives), 127 Figitidae and two Ibaliidae. New information One replacement name is proposed, Kleidotoma thomsoni Forshage, for the secondary homonym Kleidotoma tetratoma Thomson, 1861 (nec K. tetratoma (Hartig, 1841)). PMID:28325971

  20. Fail-safe bidirectional valve driver

    NASA Technical Reports Server (NTRS)

    Fujimoto, H.

    1974-01-01

    Cross-coupled diodes are added to commonly used bidirectional valve driver circuit to protect circuit and power supply. Circuit may be used in systems requiring fail-safe bidirectional valve operation, particularly in chemical- and petroleum-processing control systems and computer-controlled hydraulic or pneumatic systems.

  1. The Art of Saving a Failing School

    ERIC Educational Resources Information Center

    Stein, Les

    2012-01-01

    While the debate continues over whether to close failing schools or attempt fixing them, the author asserts that the solution most often lies in assigning strong leaders to them who will take definite and immediate action. Reviewing his own success turning around schools, he says creating a sense of urgency, unloading poor performing staff, and…

  2. Examination of a Failed Professional Learning Community

    ERIC Educational Resources Information Center

    Sims, Rachel L.; Penny, G. Richard

    2015-01-01

    Schools are using various forms of professional learning communities (PLCs) in order to increase student achievement and improve educational practices through enhanced communication and collaboration among teachers. This study examined a PLC that had too narrow a focus and failed therefore to affect student achievement. A critical shortcoming of…

  3. Where is the British national press?

    PubMed

    MacInnes, John; Rosie, Michael; Petersoo, Pille; Condor, Susan; Kennedy, James

    2007-06-01

    Although globalization has highlighted the danger of conflating state, society and nation, sociologists remain insufficiently alert to such banal nationalism. Newspapers offer a strong test case of the extent of diversity in the construction of state, national and social boundaries, since Billig and Anderson have argued they comprise a special case where their orientation to an audience simultaneously located in a state, society and nation allows them to reproduce a sense of national identity. However, despite the commonsense obviousness of the term, it proves remarkably difficult to define what the 'British national press' might comprise. Circulation density of titles varies substantially across different parts of the UK and editorial copy is altered to address diverse 'national' readerships. 'British' newspapers also circulate in other states, especially the Republic of Ireland. After reviewing how newspapers might be defined as 'national' and/or 'British', we conclude that both Anderson and Billig over-estimate the congruence, relevance and obviousness of state, society and national boundaries. If the conceptualization of such boundaries is problematic in the case of the press, it follows that it must be still more so for most other objects of sociological analysis, including that of 'society' itself.

  4. Sustainable development in British land use regulation

    SciTech Connect

    Basiago, A.D.

    1995-12-01

    Sustainable development is a new international theory of development founded on principles of futurity, environment, equity and participation. It is the legacy of twenty years of international environmental law that has established a doctrine of global trusteeship. Sustainable development has entered British land use regulation through the Maastricth Treaty; the EU`s Fifth Environmental Action Program; as well as the British government`s Planning Policy Guidance notes on land use principles, local plans, transport and historic preservation, and its white papers. The Earth Summit accord Agenda 21 is a blueprint on how to make development socially, economically and environmentally sustainable. Under its terms, Britain has prepared a national sustainable development strategy for the UN`s Commission on Sustainable Development. It features Local Agenda 21 strategies in which local authorities develop policies for sustainable development and establish partnerships with other sectors. In this paper, the Local Agenda 21 strategies of seven local authorities are evaluated according to the paradigm introduced in Agenda 21 and elaborated by Kahn that describes sustainable development as a dynamic system of integrated and interlinked economic, social and environmental sustainability. The author concludes that sustainable development in British land use regulation is guided by notions of economic development, social justice and environmental planning and not by the dynamic, integrated model of Agenda 21. 46 refs., 3 figs.

  5. Blast furnace injection developments in British Steel

    SciTech Connect

    Jukes, M.H.

    1996-12-31

    British Steel has four integrated steel works, i.e., Llanwern, Port Talbot, Scunthorpe, Teesside, with a total of ten blast furnaces, nine of which are currently operating. The furnaces range in size from the 14 meters (45 feet 11 inches) hearth diameter Redcar No. 1 furnace at Teesside (a single furnace works) to the 8.33 meters (27 feet 4 inches) hearth Queen Mary and Queen Bess furnaces at Schunthorpe, with a total of four furnaces at that works. All have injection systems installed, those at Scunthorpe being equipped with granular coal injection and all others currently working with oil injection. The driving force behind the development of blast furnace injection has been as a means for introducing reducing agents (British Steel now refers to coke plus hydrocarbon injectants as total reductants) into the process as a part substitute/supplement for top charged coke and the technology is still being developed and used for that purpose. By utilizing practical experience and observing the work of others, British Steel has been assessing blast furnace injection technology experimentally for purposes other than the introduction of reducing agents.

  6. Competition law and British natural gas regulation

    SciTech Connect

    Black, A.J.

    1992-01-01

    British Gas (BG) is a seriously successful monopolist which, since its 1986 privatisation, is acing increased regulation by the Office of Gas Supply (OFGAS). OFGAS is the first public body specifically created to regulate a European gas industry. It employs a rate-capping formula instead of the more labour intensive rate-of-retum method favoured in North America. Despite initial criticisms, OFGAS has surprised industry observers with efficacious results. This article succinctly discusses the process of natural gas industry privatisation in the United Kingdom (U.K.) and the development of a British type of [open quotes]open access.[close quotes] Contemporary British gas regulation is a distinct paradigm involving the privatisation of a vertically integrated pipeline system coupled with an altemative regulatory method. These regulatory results include lower prices for core customers and the promotion of third party direct sales within the U.K. Since Britain leads the European Community (E.C.) in common carriage provisions, the regulatory r6gime here provides a benchmark for the other Member States.

  7. Results of Trabectome Surgery Following Failed Glaucoma Tube Shunt Implantation

    PubMed Central

    Mosaed, Sameh; Chak, Garrick; Haider, Asghar; Lin, Ken Y.; Minckler, Don S.

    2015-01-01

    Abstract To evaluate the safety and efficacy of Trabectome after failed tube shunt surgery. Twenty patients with prior failed tube shunt surgery who underwent Trabectome alone were included. All patients had at least 3 months of follow-up. Outcomes measured included intraocular pressure (IOP), glaucoma medications, and secondary glaucoma surgeries. The success for Kaplan–Meier survival analysis is defined as IOP ≤21 mm Hg, IOP reduced by at least 20% from preoperative IOP, and no secondary glaucoma surgery. Mean preoperative IOP was 23.7 ± 6.4 mm Hg and mean number of glaucoma medications was 3.2 ± 1.5. At 12 months, IOP was reduced to 15.5 ± 3.2 mm Hg (P = 0.05) and number of medications was reduced to 2.4 ± 1.5 (P = 0.44). Survival rate at 12 months was 84% and 3 patients required additional glaucoma surgery with 15 patients reaching 12 months follow-up. Other than failure of IOP control and transient hypotony (IOP < 3 mm Hg) day 1 in 2 cases, there were no adverse events. Trabecular bypass procedures have traditionally been considered an approach appropriate for early-to-moderate glaucoma; however, our study indicates benefit in refractory glaucoma as well. Eyes that are prone to conjunctival scarring and hypertrophic wound healing, such as those who have failed tube shunt surgery, may benefit from procedures that avoid conjunctival incision such as Trabectome. This study indicates potential benefits in this patient population. Trabectome was safe and effective in reducing IOP at 1-year follow-up in patients with prior failed tube shunt surgery, but not effective in reducing medication reliance in these patients. PMID:26222842

  8. Analysis of failed nuclear plant components

    SciTech Connect

    Diercks, D.R.

    1992-07-01

    Argonne National Laboratory has conducted analyses of failed components from nuclear power generating stations since 1974. The considerations involved in working with and analyzing radioactive components are reviewed here, and the decontamination of these components is discussed. Analyses of four failed components from nuclear plants are then described to illustrate the kinds of failures seen in service. The failures discussed are (a) intergranular stress corrosion cracking of core spray injection piping in a boiling water reactor, (b) failure of canopy seal welds in adapter tube assemblies in the control rod drive head of a pressure water reactor, (c) thermal fatigue of a recirculation pump shaft in a boiling water reactor, and (d) failure of pump seal wear rings by nickel leaching in a boiling water reactor.

  9. Failed back surgery syndrome: current perspectives

    PubMed Central

    Baber, Zafeer; Erdek, Michael A

    2016-01-01

    The treatment of failed back surgery syndrome (FBSS) can be equally challenging to surgeons, pain specialists, and primary care providers alike. The onset of FBSS occurs when surgery fails to treat the patient’s lumbar spinal pain. Minimizing the likelihood of FBSS is dependent on determining a clear etiology of the patient’s pain, recognizing those who are at high risk, and exhausting conservative measures before deciding to go into a revision surgery. The workup of FBSS includes a thorough history and physical examination, diagnostic imaging, and procedures. After determining the cause of FBSS, a multidisciplinary approach is preferred. This includes pharmacologic management of pain, physical therapy, and behavioral modification and may include therapeutic procedures such as injections, radiofrequency ablation, lysis of adhesions, spinal cord stimulation, and even reoperations. PMID:27853391

  10. Checklist of British and Irish Hymenoptera - Chalcidoidea and Mymarommatoidea

    PubMed Central

    Dale-Skey, Natalie; Askew, Richard R.; Noyes, John S.; Livermore, Laurence

    2016-01-01

    Abstract Background A revised checklist of the British and Irish Chalcidoidea and Mymarommatoidea substantially updates the previous comprehensive checklist, dating from 1978. Country level data (i.e. occurrence in England, Scotland, Wales, Ireland and the Isle of Man) is reported where known. New information A total of 1754 British and Irish Chalcidoidea species represents a 22% increase on the number of British species known in 1978. PMID:27346954

  11. Occupational mortality in British commercial fishing, 1976–95

    PubMed Central

    Roberts, S

    2004-01-01

    Aims: To establish the causes and circumstances of all deaths occurring at work or related to work among fishermen in British commercial fishing between 1976 and 1995. Methods: A retrospective study, based on official mortality files, with a population of 440 355 fishermen-years at risk. Results: Of 616 deaths in British fishing, 454 (74%) were due to accidents at work, and 394 (87%) of these fishermen drowned. A total of 270 accidents were caused by casualties to vessels and 184 by personal accidents. There was no significant decline in the fatal accident rate, 103.1 per 100 000 fishermen-years, between 1976 and 1995. The fatal accident rate was 52.4 times higher (95% CI 42.9 to 63.8) than for all workers in Great Britain during the same period, and this relative risk increased through the 1980s up to 76.6 during 1991–95. Relative risks with the construction (12.3) and manufacturing (46.0) industries were higher than 5 and 20 respectively, during 1959–68. Trawlers foundering in adverse weather was the most frequent cause of mortality from casualties to vessels (115 deaths), and 82 of 145 personal accidents at sea arose during operations involving trawling nets. Conclusions: When compared with shore based industries, fishing remains at least as hazardous as before. Prevention should be aimed, most importantly, at the unnecessary operation of small vessels and trawling net manoeuvres in hazardous weather and sea conditions. Other measures should focus on preventing falls overboard, reducing fatigue, a more widespread use of personal flotation devices, and improvements in weather forecast evaluation. PMID:14691268

  12. Neurolysis for failed tarsal tunnel surgery.

    PubMed

    Yalcinkaya, Merter; Ozer, Utku Erdem; Yalcin, M Burak; Bagatur, A Erdem

    2014-01-01

    The purpose of the present study was to investigate the causes of failure after tarsal tunnel release and the operative findings in the secondary interventions and the outcomes. The data from 8 patients who had undergone revision surgery for failed tarsal tunnel release at least 12 months earlier were evaluated retrospectively. Only the patients with idiopathic tarsal tunnel syndrome were included, and all had unilateral symptoms. Neurophysiologic tests confirmed the clinical diagnosis of failed tarsal tunnel release in all patients. Magnetic resonance imaging revealed varicose veins within the tarsal tunnel in 1 patient (12.5%) and tenosynovitis in another (12.5%). Open tarsal tunnel release was performed in all patients, and the tibialis posterior nerve, medial and lateral plantar nerves (including the first branch of the lateral plantar nerve), and medial calcaneal nerve were released in their respective tunnels, and the septum between the tunnels was resected. The outcomes were assessed according to subjective patient satisfaction as excellent, good, fair, or poor. During revision surgery, insufficient release of the tarsal tunnel, especially distally, was observed in all the patients, and fibrosis of the tibialis posterior nerve was present in 1 (12.5%). The outcomes according to subjective patient satisfaction were excellent in 5 (62.5%), good in 2 (25%), and fair in 1 (12.5%). The fair outcome was obtained in the patient with fibrosis of the nerve. Insufficient release of the tarsal tunnel was the main cause of failed tarsal tunnel release. Releasing the 4 distinct tunnels and permitting immediate mobilization provided satisfactory results in patients with failed tarsal tunnel release.

  13. Pass-Fail: How Is It Working?

    ERIC Educational Resources Information Center

    Chase, Clinton I.; And Others

    This study investigates the pass/fail (P/F) grading system. A sample of 154 Indiana University students was interviewed. Half of the group, 77 students, had not taken any P/F courses. Of the remaining 77 students, 42% had taken only one P/F course and most of the rest from two to five courses. Results of the student interview questionnaire…

  14. Stellar Death by Weak or Failed Supernovae

    NASA Astrophysics Data System (ADS)

    Adams, Scott Michael

    Core collapse supernovae (SNe) - the violent deaths of massive stars - are among the most luminous events in the Universe and play an important role in galaxy evolution and the production and distribution of the heavy elements necessary for planet formation and life. Despite decades of effort it is still unclear how these SNe explode. While SNe have been identified with close to the maximum theoretically possible energies, the lower bounds on SN energies and luminosities are less well-constrained. There is also no requirement that the core collapse always results in a successful SN explosion. In fact, there are multiple lines of evidence that suggest that 10 - 30% of core collapses might result in failed SNe, forming a black hole without a dramatic external explosion. The primary focus of this dissertation is to explore the lower bounds of the possible explosion energies and luminosities of core-collapse SNe. I discuss three observational strategies to help understand how massive stars die. Due to the development of advanced facilities for the detection of neutrinos and gravitational waves, the next Galactic SN will offer an unprecedented opportunity to study the SN explosion mechanism. To aid preparations for this event, I model the distance, extinction, and magnitude probability distributions for a Galactic SN, its shock breakout radiation, and progenitor. I also analyze the archetypes of two types of SN "impostors" and show that they may be genuine SNe, but with energies lower than previously observed. I present results from an ambitious survey that has been monitoring a million massive stars for 7 years to search for failed SNe. I follow-up the first identified failed SN candidate and find that the massive stellar progenitor appears to have vanished leaving behind a faint, fading IR source that may be due to fallback accretion onto a newly formed black hole. Finally, I set new constraints on the fraction of core collapses that result in failed SNe.

  15. Social class and health: the puzzling counter-example of British South Asians.

    PubMed

    Williams, R; Wright, W; Hunt, K

    1998-11-01

    British South Asians (with ancestry from the Indian subcontinent) provided a puzzling exception to the British class gradient in mortality during the 1970s. On the assumption that class gradients in health are produced mainly by gradients in standard of living, this might be due to a break in the relation of class to standard of living (change in class structure), or by a break in the relation of standard of living to patterns of health behaviour and health risk (change in class lifestyles). Data on these characteristics are available from the West of Scotland Twenty-07 Study, where 159 South Asians aged 30-40 (mean age 35) were sampled alongside 319 of the general population in Glasgow. As regards changes in class structure, results indicate that the underclass thesis, which suggests that ethnic minorities are forced into less eligible jobs or into a separate labour market or into unemployment, resulting in a standard of living below that of the general population, still holds good for British South Asians in categories from social class III non-manual downwards. It does not hold good for owners of small businesses, where Sikhs and Hindus in particular have a standard of living equivalent to general population counterparts. However, prosperity is not predictable from levels of education in the subcontinent and from this and other signs it appears that a wholesale redistribution of class chances is occurring among British South Asians, disrupting inter-and intra-generational continuities in the relation between class and standard of living. There is little sign of change in class lifestyles, i.e. in the relation between standard of living and health behaviour or health risk. As yet, though, the new distribution of standard of living is affecting patterns of health behaviour and health risk more strongly than symptom experience or chronic illness, suggesting that a class gradient in health will re-emerge.

  16. White British; Dual Heritage; British Muslim: Young Britons' Conceptualisation of Identity and Citizenship

    ERIC Educational Resources Information Center

    Basit, Tehmina N.

    2009-01-01

    This paper examines young British people's conceptualisation of identity and citizenship. Data were gathered through a questionnaire survey from 442 young male and female citizens of majority and minority ethnic origins, aged 14-24 years and at different stages of education, employment and non-employment. This was followed up by in-depth…

  17. Noch Einmal:American English - British English (Once More: American English -- British English).

    ERIC Educational Resources Information Center

    Botts, M.

    1980-01-01

    Replies critically to the article by D. K. Stevenson and R. J. Brunt, "Living English: Seeing the Forest in Spite of the Trees -- On Differences between American English and British English," in this journal, issue 1979/2. A reply by Stevenson and Brunt continues the controversy. (IFS/WGA)

  18. Postpartum domperidone use in British Columbia: a retrospective cohort study

    PubMed Central

    Smolina, Kate; Morgan, Steven G.; Hanley, Gillian E.; Oberlander, Tim F.; Mintzes, Barbara

    2016-01-01

    Background: Domperidone is commonly used off-label to stimulate milk production in mothers who have low milk supply. The aim of this study was to describe trends, patterns and determinants of postpartum domperidone use. Methods: This is a retrospective, population-based study involving all women with a live birth between Jan. 1, 2002, and Dec. 31, 2011, in the province of British Columbia. We examined administrative data sets containing person-specific information on filled prescriptions and use of medical services, and we used logistic regression to examine associations between domperidone use and maternal characteristics. Results: The study population consisted of 225 532 women with 320 351 live births. The prevalence of postpartum domperidone use more than doubled between 2002 and 2011. In 2011, 1 in 3 women with a preterm birth and 1 in 5 women with a full-term birth were prescribed domperidone in the first 6 months postpartum. Women who were older, had a higher body mass index, had a chronic disease, were first-time mothers, delivered more than 1 baby (multiple pregnancy), had a preterm birth or had a cesarian delivery were more likely to fill a postpartum domperidone prescription. Interpretation: We found an increase in postpartum domperidone use over a 10-year period. More research is needed on maternal and infant health outcomes. PMID:27280111

  19. Computer Programming: Fail Fast to Learn Sooner

    NASA Astrophysics Data System (ADS)

    Brito, Miguel A.; de Sá-Soares, Filipe

    Computer programming is not only to know about the languages or the processes, it is essentially to know how to do it. This involves a constructivist approach in learning. For a newbie in computer programming it is hard to understand the difference between know-about disciplines and the know-how-to-do-it ones. This leads to failure because when they understand they aren't able to solve a programming problem it is usually too late to catch all the time meanwhile lost. Our solution is to get them to fail soon enough. This way they still have time to recover from an eventually bad start.

  20. Tropical skin diseases in British military personnel.

    PubMed

    Bailey, Mark S

    2013-09-01

    Skin complaints are common in travellers to foreign countries and are responsible for up to 25% of medical consultations by military personnel during deployments in the tropics. They also have relatively high rates of field hospital admission, medical evacuation and referral to UK Role 4 healthcare facilities. Non-infectious tropical skin diseases include sunburn, heat rash, arthropod bites, venomous bites, contact dermatitis and phytophotodermatitis. During tropical deployments skin infections that commonly occur in military personnel may become more frequent, severe and difficult to treat. Several systemic tropical infections have cutaneous features that can be useful in making early diagnoses. Tropical skin infections such as cutaneous larva migrans, cutaneous myiasis, cutaneous leishmaniasis and leprosy do occur in British troops and require specialist clinical management. This illustrated review focuses on the most significant tropical skin diseases that have occurred in British military personnel in recent years. Clinical management of these conditions on deployments would be improved and medical evacuations could be reduced if a military dermatology 'reach-back' service (including a telemedicine facility) was available.

  1. Are We There yet? Intercultural Encounters with British Studies

    ERIC Educational Resources Information Center

    Dasli, Maria

    2012-01-01

    This paper aims to contribute to the current debate on British Studies from the perspective of eight international students attending a British Studies module in part completion of a foundation/access programme in the UK. Drawing on three sets of in-depth student interviews and 15 classroom observations used to triangulate findings, the analysis…

  2. Problem Gambling Treatment within the British National Health Service

    ERIC Educational Resources Information Center

    Rigbye, Jane; Griffiths, Mark D.

    2011-01-01

    According to the latest British Gambling Prevalence Survey, there are approximately 300,000 adult problem gamblers in Great Britain. In January 2007, the "British Medical Association" published a report recommending that those experiencing gambling problems should receive treatment via the National Health Service (NHS). This study…

  3. The Limits of Movement Politics: The Case of British Feminism.

    ERIC Educational Resources Information Center

    Stetson, Dorothy M.

    Analysis of the British feminist movement from 1850 to 1975 reveals a constant struggle by feminists for equality in the face of legal and social restrictions and a corresponding lack of response by the British government to movement demands. The political organization of the feminist movement is described in four phases. During the first phase,…

  4. BCASP and the Evolution of School Psychology in British Columbia

    ERIC Educational Resources Information Center

    Agar, Douglas J.

    2016-01-01

    Since 1992, the British Columbia Association of School Psychologists (BCASP) has been the professional body for school psychologists in British Columbia. In the intervening 24 years, BCASP has been very successful in performing the dual roles of a certifying body and a professional development organization for school psychologists in British…

  5. 78 FR 72598 - Airworthiness Directives; British Aerospace Regional Aircraft Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; British Aerospace... directive (AD) for British Aerospace Regional Aircraft Jetstream Series 3101 and Jetstream Model 3201... after receipt. FOR FURTHER INFORMATION CONTACT: Taylor Martin, Aerospace Engineer, FAA, Small...

  6. The Misrepresentation of Religion in Modern British (Religious) Education

    ERIC Educational Resources Information Center

    Barnes, Philip

    2006-01-01

    The purpose of this paper is to articulate a new perspective on British multi-faith religious education that both complements and, in part, subsumes existing critiques. My argument, while controversial, is straightforward: it is that British religious education has misrepresented the nature of religion in efforts to commend itself as contributing…

  7. Unions between Foreign Language and Business: British Patterns.

    ERIC Educational Resources Information Center

    Scott, James Calvert

    Traditional British attitudes toward foreigners, which are now being challenged by current economic realities, and the increasing internationalization of British business, which magnifies the need for employees to communicate effectively with people from other countries and cultures, are discussed. A brief overview is provided that covers recent…

  8. Britishness as Racist Nativism: A Case of the Unnamed "Other"

    ERIC Educational Resources Information Center

    Smith, Heather Jane

    2016-01-01

    The construct of Britishness, as with nationalism elsewhere in the world, although amorphous and permeable over time, continues to be used by politicians and the media as a powerful exclusionary force. Moreover in England, fundamental British values (FBV), its most recent and official incarnation, now hold particular currency in education policy…

  9. Knowledge, Character and Professionalisation in Nineteenth-Century British Science

    ERIC Educational Resources Information Center

    Ellis, Heather

    2014-01-01

    Historians have frequently referred to the British Association for the Advancement of Science as an institution that had the professionalisation of British science as its chief aim. This article seeks to complicate this picture by asking what, if any, concept of "professionalisation" would have been understood by nineteenth-century…

  10. Teaching Psychology in American and British Universities: Some Personal Impressions.

    ERIC Educational Resources Information Center

    Remington, Bob; Green, Patrick

    1988-01-01

    British psychologists, who have taught in both the United States and Great Britain, compare the teaching of psychology in British and U.S. universities. Discussing similarities and differences in course structure, curriculum, teaching methods, and evaluation procedures, they suggest ways in which each system could benefit from some of the other's…

  11. British and Finnish Baseball: International Variations on an American Pastime

    ERIC Educational Resources Information Center

    Williams, Emyr W.; Romar, Jan-Erik; Hartman, Michael

    2010-01-01

    Both British and Finnish baseball are easy to introduce, as the specific skills involved in both sports are identical to those used in traditional baseball. If students have the skills to play traditional baseball, they have the skills to play British and Finnish baseball as well. After a brief overview of the unique rules and strategies of these…

  12. The Politics of Britishness: Multiculturalism, Schooling and Social Cohesion

    ERIC Educational Resources Information Center

    Keddie, Amanda

    2014-01-01

    This paper is set against a backdrop of contemporary concerns about Britishness. It explores the dominant view that unprecedented levels of cultural diversity within western contexts such as the UK are undermining social cohesion and are attributable to minority groups' failure to connect or assimilate with mainstream "British" (read…

  13. Soaps and Suspicious Activity: Dramatic Experiences in British Classrooms.

    ERIC Educational Resources Information Center

    Ferree, Angela M.

    2001-01-01

    Offers examples of dramatic experiences (student produced soap operas) in two classrooms in British comprehensive secondary schools. Concludes that students in other countries would find such experiences as meaningful and enjoyable as their British counterparts. Notes that the two teachers managed to be flexible, appropriating effective…

  14. Contagious ecthyma in mountain goat of coastal British Columbia.

    PubMed

    Hebert, D M; Samuel, W M; Smith, G W

    1977-04-01

    Contagious ecthyma has been reported previously from mountain goat (Oreamnos americanus) in one restricted area of eastern British Columbia. A second focus of infection is reported for mountain goat from western British Columbia. Diagnosis was based on appearance of lesions at necropsy, histopathology and demonstration of poxvirus with the electron microscope. The epizootiology of this infection in mountain goat is discussed briefly.

  15. Prospects for Adult Literacy Policy in British Columbia.

    ERIC Educational Resources Information Center

    Darville, Richard

    1989-01-01

    Intended to assist in the formulation of effective policies for adult literacy in British Columbia, this paper reviews the current discussion of adult literacy policy and programming across Canada. It also reviews existing policies in Canada and in British Columbia, in education ministries, and in other ministries with interests and activities…

  16. Academic Freedom, Autonomy and Accountability in British Universities.

    ERIC Educational Resources Information Center

    Berdahl, Robert

    1990-01-01

    This paper argues that, using Eric Ashby's writing on academic freedom and autonomy and Burton Clark's essay on different modes of coordination, the British government has unnecessarily terminated the University Grants Committee and, in its overreliance on market forces, is threatening the future academic integrity of British universities.…

  17. Shakespearean Intertexts and European Identities in Contemporary Black British Fiction

    ERIC Educational Resources Information Center

    Muñoz-Valdivieso, Sofía

    2012-01-01

    The article analyses the presence of William Shakespeare as intertext in three recent novels by black British writers which deploy the work of the Bard as they explore British and European identities. Caryl Phillips's "The Nature of Blood" recreates an Othello-like figure who in early Modern Venice struggles to come to terms with his…

  18. Mitochondrial protein hyperacetylation in the failing heart

    PubMed Central

    Horton, Julie L.; Martin, Ola J.; Lai, Ling; Richards, Alicia L.; Vega, Rick B.; Leone, Teresa C.; Pagliarini, David J.; Muoio, Deborah M.; Bedi, Kenneth C.; Coon, Joshua J.

    2016-01-01

    Myocardial fuel and energy metabolic derangements contribute to the pathogenesis of heart failure. Recent evidence implicates posttranslational mechanisms in the energy metabolic disturbances that contribute to the pathogenesis of heart failure. We hypothesized that accumulation of metabolite intermediates of fuel oxidation pathways drives posttranslational modifications of mitochondrial proteins during the development of heart failure. Myocardial acetylproteomics demonstrated extensive mitochondrial protein lysine hyperacetylation in the early stages of heart failure in well-defined mouse models and the in end-stage failing human heart. To determine the functional impact of increased mitochondrial protein acetylation, we focused on succinate dehydrogenase A (SDHA), a critical component of both the tricarboxylic acid (TCA) cycle and respiratory complex II. An acetyl-mimetic mutation targeting an SDHA lysine residue shown to be hyperacetylated in the failing human heart reduced catalytic function and reduced complex II–driven respiration. These results identify alterations in mitochondrial acetyl-CoA homeostasis as a potential driver of the development of energy metabolic derangements that contribute to heart failure. PMID:26998524

  19. The evaluation of the failed shoulder arthroplasty.

    PubMed

    Wiater, Brett P; Moravek, James E; Wiater, J Michael

    2014-05-01

    As the incidence of shoulder arthroplasty continues to rise, the orthopedic shoulder surgeon will be increasingly faced with the difficult problem of evaluating a failed shoulder arthroplasty. The patient is usually dissatisfied with the outcome of the previous arthroplasty as a result of pain, but may complain of poor function due to limited range of motion or instability. A thorough and systematic approach is necessary so that the most appropriate treatment pathway can be initiated. A comprehensive history and physical examination are the first steps in the evaluation. Diagnostic studies are numerous and include laboratory values, plain radiography, computed tomography, ultrasound imaging, joint aspiration, nuclear scans, and electromyography. Common causes of early pain after shoulder arthroplasty include technical issues related to the surgery, such as malposition or improper sizing of the prosthesis, periprosthetic infection, neurologic injury, and complex regional pain syndrome. Pain presenting after a symptom-free interval may be related to chronic periprosthetic infection, component wear and loosening, glenoid erosion, rotator cuff degeneration, and fracture. Poor range of motion may result from inadequate postoperative rehabilitation, implant-related factors, and heterotopic ossification. Instability is generally caused by rotator cuff deficiency and implant-related factors. Unfortunately, determining the cause of a failed shoulder arthroplasty can be difficult, and in many situations, the source of pain and disability is multifactorial.

  20. What do we do after an implant fails? A review of treatment alternatives for failed implants.

    PubMed

    Machtei, Eli E

    2013-01-01

    The problem of failed implants cannot be overlooked. The purpose of this paper is to explore treatment alternatives for failed implants and their strengths and shortcomings. A comprehensive literature search was performed using PubMed and a manual search. Only five studies were identified that explored treatment in sites where implants had failed. In all five studies, the treatment alternative tested was the placement of a new implant in the failed site. The overall survival rate for such implants ranged from 71% to 92.3%. Four other alternatives are also discussed in light of data derived from other studies on the survival of various treatment strategies. These include: a continuation of the original plan using the remaining implants, modification of treatment to a tooth-supported fixed partial denture (FPD) or to a hybrid tooth-implant? supported FPD, or modification to a removable prosthesis. The selection of an appropriate alternative for failed implants is complex and involves biologic, mechanical, and psychologic considerations along with financial aspects. This should be a team decision with the patient's opinion included.

  1. Migrant labour, racism and the British National Health Service.

    PubMed

    Kyriakides, Christopher; Virdee, Satnam

    2003-11-01

    This study explores the dynamics of racism, specifically its generation and reproduction as an ideology, and its role in affecting the reception and occupational location of migrant medical labour in Britain. It is argued that the treatment of 'overseas doctors' in Britain draws on a complex interplay between racism and nationalism underpinned by the historical construction of 'welfarism' as a moral legitimator of 'Britishness'. Through an exploration of internal and external immigration controls introduced with the aim of regulating migrant labour, we demonstrate how British social policy and elite discourses of 'race' combine to construct moral prescriptions of threat such that migrants and British-born 'non-whites' entering the British medical profession are forced to negotiate 'saviour/pariah' ascriptions indicative of discriminatory but contradictory processes specific to the operation of the British National Health Service as a normative institution.

  2. Status Review of the Marbled Murrelet (Brachyramphus marmoratus) in Alaska and British Columbia

    USGS Publications Warehouse

    Piatt, J.F.; Kuletz, K.J.; Burger, A.E.; Hatch, Shyla A.; Friesen, V.L.; Birt, T.P.; Arimitsu, M.L.; Drew, G.S.; Harding, A.M.A.; Bixler, K.S.

    2007-01-01

    The Marbled Murrelet (Brachyramphus marmoratus) is a small, diving seabird inhabiting inshore waters of the Northeastern Pacific Ocean. This species feeds on small, schooling fishes and zooplankton, and nests primarily on the moss-covered branches of large, old-growth conifers, and also, in some parts of its range, on the ground. We reviewed existing information on this species to evaluate its current status in the northern part of its range-Alaska (U.S.) and British Columbia (Canada). Within the southern part of its range (Washington, Oregon, and California, U.S.), the Marbled Murrelet was listed as a threatened species under the Endangered Species Act (ESA) in 1993, and the U.S. Fish and Wildlife Service (USFWS) needed information on the species throughout its range for ESA deliberations. We compiled published information on the conservation status, population biology, foraging ecology, population genetics, population status and trends, demography, marine and nesting habitat characteristics, threats, and ongoing conservation efforts for Marbled Murrelets in Alaska and British Columbia. We conducted a new genetic study using samples from a segment of the range that had not been included in previous studies (Washington, Oregon) and additional nuclear intron and microsatellite markers. We also analyzed available at-sea survey data from several locations for trend. To understand the reasonableness of the empirical trend data, we developed demographic models incorporating stochasticity to discern what population trends were possible by chance. The genetic studies substantially confirmed previous findings on population structure in the Marbled Murrelet. Our present work finds three populations: (1) one comprising birds in the central and western Aleutian Islands; (2) one comprising birds in central California; and (3) one comprising birds within the center of the range from the eastern Aleutians to northern California. Our knowledge of genetic structure within this

  3. A Solution to ``Too Big to Fail''

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-10-01

    Its a tricky business to reconcile simulations of our galaxys formation with our current observations of the Milky Way and its satellites. In a recent study, scientists have addressed one discrepancy between simulations and observations: the so-called to big to fail problem.From Missing Satellites to Too Big to FailThe favored model of the universe is the lambda-cold-dark-matter (CDM) cosmological model. This model does a great job of correctly predicting the large-scale structure of the universe, but there are still a few problems with it on smaller scales.Hubble image of UGC 5497, a dwarf galaxy associated with Messier 81. In the missing satellite problem, simulations of galaxy formation predict that there should be more such satellite galaxies than we observe. [ESA/NASA]The first is the missing satellites problem: CDM cosmology predicts that galaxies like the Milky Way should have significantly more satellite galaxies than we observe. A proposed solution to this problem is the argument that there may exist many more satellites than weve observed, but these dwarf galaxies have had their stars stripped from them during tidal interactions which prevents us from being able to see them.This solution creates a new problem, though: the too big to fail problem. This problem states that many of the satellites predicted by CDM cosmology are simply so massive that theres no way they couldnt have visible stars. Another way of looking at it: the observed satellites of the Milky Way are not massive enough to be consistent with predictions from CDM.Artists illustration of a supernova, a type of stellar feedback that can modify the dark-matter distribution of a satellite galaxy. [NASA/CXC/M. Weiss]Density Profiles and Tidal StirringLed by Mihai Tomozeiu (University of Zurich), a team of scientists has published a study in which they propose a solution to the too big to fail problem. By running detailed cosmological zoom simulations of our galaxys formation, Tomozeiu and

  4. The Special Relationship: The United States as the British Have Seen It. A Selective Reading List by British Writers.

    ERIC Educational Resources Information Center

    Wright, Esmond, Comp.

    The selective annotated bibliography is a reader's guide to aspects of the American past and present as seen by British writers since the 1940s. Approximately 250 entries provide a sampling of how British students of United States studies perceive the New World. Childrens books are omitted. Nine categories are organized alphabetically by author.…

  5. When continuous positive airway pressure (CPAP) fails

    PubMed Central

    Virk, Jagdeep S.

    2016-01-01

    Obstructive sleep apnoea (OSA) is increasingly prevalent, particularly in the context of the obesity epidemic, and is associated with a significant social, health and economic impact. The gold standard of treatment for moderate to severe OSA is continuous positive airway pressure (CPAP). However compliance rates can be low. Methodology to improve patient tolerance to CPAP alongside with alternative, non-surgical and surgical, management strategies are discussed. All patients that fail CPAP therapy would benefit from formal upper airway evaluation by the otolaryngologist to identify any obvious causes and consider site-specific surgical therapies. Patient selection is integral to ensuring successful outcomes. A multidisciplinary team is needed to manage these patients. PMID:27867577

  6. Terrestrial-passage theory: failing a test.

    PubMed

    Reed, Charles F; Krupinski, Elizabeth A

    2009-01-01

    Terrestrial-passage theory proposes that the 'moon' and 'sky' illusions occur because observers learn to expect an elevation-dependent transformation of visual angle. The transformation accompanies daily movement through ordinary environments of fixed-altitude objects. Celestial objects display the same visual angle at all elevations, and hence are necessarily non-conforming with the ordinary transformation. On hypothesis, observers should target angular sizes to appear greater at elevation than at horizon. However, in a sample of forty-eight observers there was no significant difference between the perceived angular size of a constellation of stars at horizon and that predicted for a specific elevation. Occurrence of the illusion was not restricted to those observers who expected angular expansion. These findings fail to support the terrestrial-passage theory of the illusion.

  7. Fail-over file transfer process

    NASA Technical Reports Server (NTRS)

    Semancik, Susan K. (Inventor); Conger, Annette M. (Inventor)

    2005-01-01

    The present invention provides a fail-over file transfer process to handle data file transfer when the transfer is unsuccessful in order to avoid unnecessary network congestion and enhance reliability in an automated data file transfer system. If a file cannot be delivered after attempting to send the file to a receiver up to a preset number of times, and the receiver has indicated the availability of other backup receiving locations, then the file delivery is automatically attempted to one of the backup receiving locations up to the preset number of times. Failure of the file transfer to one of the backup receiving locations results in a failure notification being sent to the receiver, and the receiver may retrieve the file from the location indicated in the failure notification when ready.

  8. Revision of Failed Artroscopic Bankart Repairs

    PubMed Central

    Muiño, José María Silberberg; Gimenez, Martín Alejandro; Salvucci, Mauro Gabriel Maroa; Ferro, Diego; Rullan, Ramón Muiña

    2017-01-01

    Objectives: To present our functional outcomes from patients treated arthroscopically for a failed Bankart repair, using suture anchors and capsulolabral tissue only. Methods: Series of 22 patients presented with a recurrence of instability after a previous stabilization surgery (3 Latarjet, Bankart 19). We treated them by a an all-arthroscopic procedure, avoiding bone grafts, when glenoid track was found to be enough to proceed. The failure was associated with trauma in 11 patients, a non-anatomic repair in 6 patients, capsular laxity in 4 patients and a non-union of the coracoid graft in 1 patient. Revision surgery included: Bankart repair with anchors in 17 cases, a posterior-inferior capsulo-labral plication in one case, and 5 remplissages. In 4 cases subscapularis augmentation was used because of poor capsular quality. Screw removal was necessary when treating the non-union case. Patients were followed-up by a minimum of 23 months (range 23-26), and evaluated by the UCLA Test, SS test and Rowe score. Results: Thirteen patients had an excellent result, 6 good, 2 satisfactory and one bad result, according to UCLA score. The mean Rowe score was 90.4, at final follow up. The Simple Shoulder Test went from an 8 preoperative to an 11 postoperative, mean scores. 19 of 22 patients returned to the same level of activity prior to the injury. Complications: recurrence in 2 cases, subluxation in 2 and one shoulder stiffness that required an arthrolysis. Conclusion: An arthroscopic revision surgery, after a failed Bankart repair, presents satisfactory results in selected patients. Arthroscopic vision allows a correct diagnosis of injuries as possible causes of failure and subsequent treatment.

  9. The quick and the dead: "managing" inpatient care in British Columbia hospitals, 1969-1995/96.

    PubMed Central

    McGrail, K M; Evans, R G; Barer, M L; Sheps, S B; Hertzman, C; Kazanjian, A

    2001-01-01

    OBJECTIVE: To examine changes in hospital use in British Columbia during a decade of capacity reductions. DATA SOURCES/STUDY SETTING: The data used are all separation records for British Columbia hospitals for the years 1969, 1978, 1985/86, 1993/94, and 1995/96. Separation records include acute care, rehabilitation, extended care, and surgical day care hospital encounters in British Columbia that were concluded during the years of interest. STUDY DESIGN: Analyses were based on per capita use of services for five-year age groups of the population to ages 90+; the emphasis was on looking at changes in the use of specific types of hospital services over the 26 years of study, with a particular focus on the most recent decade. DATA COLLECTION/EXTRACTION METHODS: Data were extracted from hospital separations files owned by the British Columbia Ministry of Health and housed at the Centre for Health Services and Policy Research. All separation records for the years of interest were included in the study. PRINCIPAL FINDINGS: Acute care use continued to fall over the last decade. The rate of decline increased during the last time period of study and affected seniors to the same degree as younger patients. At the same time, use of extended care decreased, compared to steady increases in earlier years. The result was that by 1995/96 nearly 40 percent of inpatient days were used by people who died in hospital, compared to 9 percent in 1969. These people, however, still represent a small proportion of separations. CONCLUSIONS: The "bed blocker" problem common to many hospital systems appears to have been largely alleviated in British Columbia over the decade 1985-95. The concurrent decrease in extended care use, however, makes it difficult to say where and how these people are now being cared for. Care for the dying has become a bigger issue for hospitals, but whether this is because of heroic interventions at the end of life is not clear. A "top-down," capacity

  10. -Graphy: The Remains of a British Discipline

    ERIC Educational Resources Information Center

    Chapman, Graham P.

    2007-01-01

    Within Britain, geography as a discipline has been criticized recently for failing either to add to or teach knowledge about the world at large. Instead it has concentrated first at university and then in schools on spatial social science, with examples drawn overwhelmingly from the white Western world. The recent history of geography is reviewed…

  11. Telemedicine in the British Antarctic survey.

    PubMed

    Grant, Iain C

    2004-12-01

    Medicine in the Antarctic is probably the most isolated situation in which a doctor can practise, differing in degree of severity even from that of the Arctic region. The increasing use of Telemedicine has helped to reduce this isolation and to improve access to secondary healthcare for those who live in the most remote bases in the world. The article describes the way in which Antarctic Telemedicine has evolved in the British Antarctic survey, outlining the use of low cost and low technology systems to improve the availability of emergency advice, both to the doctor and to isolated field parties, specialist consultation, medical education, and healthcare records. The Antarctic is a useful proving ground for technologies which may have applications in space and other extreme and isolated environments.

  12. Metaphyseal osteopathy in a British Shorthair cat.

    PubMed

    Adagra, Carl; Spielman, Derek; Adagra, Angela; Foster, Darren J

    2015-04-01

    Metaphyseal osteopathy, otherwise known as hypertrophic osteodystrophy, is a disease that causes pyrexia and lethargy accompanied by pain in the thoracic and pelvic limbs of rapidly growing large-breed dogs. While metaphyseal osteopathy has been descibed in association with slipped capital femoral epiphysis in cats, it has not previously been reported as a cause of limb pain and pyrexia in this species. A 7-month-old British Shorthair cat presented with a 1 month history of pyrexia, lethargy and pain in all limbs. Investigation included radiographs of the limbs and chest, abdominal ultrasound, serum biochemical analysis, haematology, bone biopsy, joint fluid aspiration and cytology. Findings were consistent with a diagnosis of metaphyseal osteopathy. The cat's clinical signs resolved following the administration of prednisolone. Symptoms recurred 1 month after the cessation of prednisolone therapy, but resolved when administration was resumed.

  13. GM2 gangliosidosis in British Jacob sheep.

    PubMed

    Wessels, M E; Holmes, J P; Jeffrey, M; Jackson, M; Mackintosh, A; Kolodny, E H; Zeng, B J; Wang, C B; Scholes, S F E

    2014-01-01

    GM2 gangliosidosis (Tay-Sachs disease) was diagnosed in 6- to 8-month-old pedigree Jacob lambs from two unrelated flocks presenting clinically with progressive neurological dysfunction of 10 day's to 8 week's duration. Clinical signs included hindlimb ataxia and weakness, recumbency and proprioceptive defects. Histopathological examination of the nervous system identified extensive neuronal cytoplasmic accumulation of material that stained with periodic acid--Schiff and Luxol fast blue. Electron microscopy identified membranous cytoplasmic bodies within the nervous system. Serum biochemistry detected a marked decrease in hexosaminidase A activity in the one lamb tested, when compared with the concentration in age matched controls and genetic analysis identified a mutation in the sheep hexa allele G444R consistent with Tay-Sachs disease in Jacob sheep in North America. The identification of Tay-Sachs disease in British Jacob sheep supports previous evidence that the mutation in North American Jacob sheep originated from imported UK stock.

  14. Homosexual parents in British custody appeals.

    PubMed

    Cameron, Paul

    2003-04-01

    6 British child custody appeal cases including a homosexual parent were compared with 6 randomly drawn appeal cases between heterosexual parents for parental and mental instability, partners' instability, residential instability, criminality, and lying, and having harmed the children and exposing children to harms. In 3 of the 6 cases the homosexual or his associates were recorded as engaging in criminality, in another 2 cases with lying. In one of the 6 homosexual cases the children were recorded as harmed. The 9 recorded harms or probable harms to children in cases involving a homosexual parent were attributed to the homosexual or her associates: children were recorded as harmed and exposed to the harm of neglect in one of the 6 comparison cases.

  15. Mercury, cadmium, and lead in British otters

    SciTech Connect

    Mason, C.F.; Last, N.I.; Macdonald, S.M.

    1986-12-01

    Otters (subfamily Lutrinae), at the top of the food chain and feeding largely on fish, are likely to be especially vulnerable to the effects of bioaccumulating pollutants, while their aquatic habitat is often a sink for such chemicals derived from agricultural, industrial and domestic sources. The European otter (Lutra lutra) has shown substantial declines through much of its range over the past 30 years, which have been attributed to pollution by organochlorines. There are few published data on metals in tissues of European otters and these refer only to mercury. The present paper reports on burdens of mercury, cadmium and lead in tissues of a sample of British otters collected between 1982 and 1984.

  16. Origin of British and Irish mammals: disparate post-glacial colonisation and species introductions

    NASA Astrophysics Data System (ADS)

    Montgomery, W. Ian; Provan, Jim; McCabe, A. Marshal; Yalden, Derek W.

    2014-08-01

    ecological divergence in Ireland in comparison to Britain and continental Europe, were also those which arrived in Ireland very early in the Holocene either with or without the assistance of people. Cold tolerant mammal species recolonized quickly after LGM but disappeared, potentially as a result of a short period of rapid warming. Other early arrivals were less cold tolerant and succumbed to the colder conditions during the Younger Dryas or shortly after the start of the Holocene (11.5 kya), or the area of suitable habitat was insufficient to sustain a viable population especially in larger species. Late Pleistocene mammals in Ireland were restricted to those able to colonize up to ca 15 kya, probably originating from adjacent areas of unglaciated Britain and land now below sea level, to the south and west (of Ireland). These few, early colonizers retain genetic diversity which dates from before the LGM. Late Pleistocene Ireland, therefore, had a much depleted complement of mammal species in comparison to Britain. Mammal species, colonising predominantly from southeast and east Europe occupied west Europe only as far as Britain between ca 15 and 8 kya, were excluded from Ireland by the Irish and Celtic Seas. Smaller species in particular failed to colonise Ireland. Britain being isolated as an island from ca. 8 kya has similar species richness and composition to adjacent lowland areas of northwest continental Europe and its mammals almost all show strongest genetic affinity to populations in neighbouring continental Europe with a few retaining genotypes associated with earlier, western lineages. The role of people in the deliberate introduction of mammal species and distinct genotypes is much more significant with regards to Ireland than Britain reflecting the larger species richness of the latter and its more enduring land link with continental Europe. The prime motivation of early people in moving mammals was likely to be resource driven but also potentially cultural; as

  17. Proteomic analysis of membrane microdomains derived from both failing and non-failing human hearts.

    PubMed

    Banfi, Cristina; Brioschi, Maura; Wait, Robin; Begum, Shajna; Gianazza, Elisabetta; Fratto, Pasquale; Polvani, Gianluca; Vitali, Ettore; Parolari, Alessandro; Mussoni, Luciana; Tremoli, Elena

    2006-03-01

    Eukaryotic cells plasma membranes are organized into microdomains of specialized function such as lipid rafts and caveolae, with a specific lipid composition highly enriched in cholesterol and glycosphingolipids. In addition to their role in regulating signal transduction, multiple functions have been proposed, such as anchorage of receptors, trafficking of cholesterol, and regulation of permeability. However, an extensive understanding of their protein composition in human heart, both in failing and non-failing conditions, is not yet available. Membrane microdomains were isolated from left ventricular tissue of both failing (n = 15) and non-failing (n = 15) human hearts. Protein composition and differential protein expression was explored by comparing series of 2-D maps and subsequent identification by LC-MS/MS analysis. Data indicated that heart membrane microdomains are enriched in chaperones, cytoskeletal-associated proteins, enzymes and protein involved in signal transduction pathway. In addition, differential protein expression profile revealed that 30 proteins were specifically up- or down-regulated in human heart failure membrane microdomains. This study resulted in the identification of human heart membrane microdomain protein composition, which was not previously available. Moreover, it allowed the identification of multiple proteins whose expression is altered in heart failure, thus opening new perspectives to determine which role they may play in this disease.

  18. Learning Factor Models of Students at Risk of Failing in the Early Stage of Tertiary Education

    ERIC Educational Resources Information Center

    Gray, Geraldine; McGuinness, Colm; Owende, Philip; Hofmann, Markus

    2016-01-01

    This paper reports on a study to predict students at risk of failing based on data available prior to commencement of first year. The study was conducted over three years, 2010 to 2012, on a student population from a range of academic disciplines, n=1,207. Data was gathered from both student enrollment data and an online, self-reporting,…

  19. Examination of the factor structure of the Schizotypal Personality Questionnaire among British and Trinidadian adults.

    PubMed

    Barron, David; Swami, Viren; Towell, Tony; Hutchinson, Gerard; Morgan, Kevin D

    2015-01-01

    Much debate in schizotypal research has centred on the factor structure of the Schizotypal Personality Questionnaire (SPQ), with research variously showing higher-order dimensionality consisting of two to seven dimensions. In addition, cross-cultural support for the stability of those factors remains limited. Here, we examined the factor structure of the SPQ among British and Trinidadian adults. Participants from a White British subsample (n = 351) resident in the UK and from an African Caribbean subsample (n = 284) resident in Trinidad completed the SPQ. The higher-order factor structure of the SPQ was analysed through confirmatory factor analysis, followed by multiple-group analysis for the model of best fit. Between-group differences for sex and ethnicity were investigated using multivariate analysis of variance in relation to the higher-order domains. The model of best-fit was the four-factor structure, which demonstrated measurement invariance across groups. Additionally, these data had an adequate fit for two alternative models: (a) 3-factor and (b) modified 4-factor model. The British subsample had significantly higher scores across all domains than the Trinidadian group, and men scored significantly higher on the disorganised domain than women. The four-factor structure received confirmatory support and, importantly, support for use with populations varying in ethnicity and culture.

  20. Mortality in an extended follow-up of British coal workers

    NASA Astrophysics Data System (ADS)

    MacCalman; L; Miller; G, B.

    2009-02-01

    The Pneumoconiosis Field Research (PFR) programme was established in the 1950s, to evaluate effects of coal mining exposures on the health and mortality of British coal workers. Surveys of working miners were carried out at 5-yearly intervals, initially in 24 collieries but later concentrating on 10, collecting detailed work histories and health information for each recruit. Here we report on cause-specific mortality in a cohort of almost 18,000 men from 10 British collieries, followed up for periods up to 47 years, yielding over 516,000 life-years of follow-up. External analyses compared cause-specific death rates in the cohort to those of the population of the regions in which the collieries were situated, using Standardised Mortality Ratios (SMRs). The causes investigated included lung cancer, stomach cancer, non-malignant respiratory disorders and cardiovascular disorders. SMRs showed evidence of an initial healthy worker effect diminishing over time. Several causes, including non-malignant respiratory disease and lung cancer, showed a significant deficit of mortality at the start of the study period with an excess in the latter part of the follow-up period. In these results, effects of working conditions are likely to be confounded with smoking habits. Overall, we believe our results may be generalised to the British coal industry since nationalisation.

  1. Retirement migration, the 'other' story: caring for frail elderly British citizens in Spain.

    PubMed

    Hall, Kelly; Hardill, Irene

    2016-03-01

    Recent years have seen a growth in research on retirement/lifestyle migration to Spain, however this has tended to focus on the reasons for moving, as well as the lifestyles adopted as part of a healthy and active retirement. However, ageing in Spain can bring challenges as a person's resources for independent living diminish. This paper draws on narrative interviews with vulnerable older British people in Spain, focusing on those who have encountered a severe decline in health, are frail and in need of care. It looks at the formal and informal networks and agencies that support these individuals, in particular the resources and strategies they employ to access care. Drawing on a framework of care provision developed by Glucksmann and Lyons, four broad modes of provision for old age care used by older British people in Spain are identified: state/public, family/community, voluntary/not-for-profit and market/for-profit. The paper argues that there are language, cultural, spatial and financial barriers when accessing care in Spain as an older British citizen. It is concluded that there are some frail, vulnerable people that may fall through a support gap, whereby they are no longer the responsibility of UK welfare services, yet not fully recognised in their new country of residence, and asks if more should be done to support this population.

  2. Supply and distribution of primary healthcare registered nurses in british columbia.

    PubMed

    Wong, Sabrina T; Watson, Diane E; Young, Ella; Mooney, Dawn

    2009-11-01

    WHAT DID WE DO?: This study uses an existing data source to (a) describe the population and geographic distribution of registered nurses (RNs) working in primary healthcare (PHC) in British Columbia, (b) compare this workforce to PHC physicians and (c) assess the distribution of PHC-RNs relative to population health status. WHAT DID WE LEARN?: Of the 27,570 practising RNs in British Columbia in 2000, there were 3,179 (12%) in the PHC workforce. This translates into 147 people per practising RN and 1,277 people per PHC-RN. In 2000, there were 990 people per PHC physician. PHC-RNs represented 43% of the combined PHC workforce of physicians and RNs. A large proportion (47%) of PHC-RNs worked in community health centres, whereas less than 2% worked in physicians' offices. Geographic distribution of PHC-RNs is similar to the distribution of PHC physicians and is not associated with population health status. WHAT ARE THE IMPLICATIONS?: There seem to be sufficient PHC-RNs to implement policy objectives in support of interdisciplinary PHC teams, but physicians and nurses will increasingly need to practice in the same location or have access to electronic information systems to support coordination, continuity and comprehensiveness of PHC. The PHC workforce could be better deployed to align with population health status.

  3. The emergence and spread of finch trichomonosis in the British Isles

    PubMed Central

    Lawson, Becki; Robinson, Robert A.; Colvile, Katie M.; Peck, Kirsi M.; Chantrey, Julian; Pennycott, Tom W.; Simpson, Victor R.; Toms, Mike P.; Cunningham, Andrew A.

    2012-01-01

    Finch trichomonosis, caused by the protozoal parasite Trichomonas gallinae, was first recognized as an emerging infectious disease of British passerines in 2005. The first year of seasonal epidemic mortality occurred in 2006 with significant declines of greenfinch Carduelis chloris and chaffinch Fringilla coelebs populations. Here, we demonstrate that large-scale mortality, principally of greenfinch, continued in subsequent years, 2007–2009, with a shifting geographical distribution across the British Isles over time. Consequent to the emergence of finch trichomonosis, the breeding greenfinch population in Great Britain has declined from ca 4.3 million to ca 2.8 million birds and the maximum mean number of greenfinches (a proxy for flock size) visiting gardens has declined by 50 per cent. The annual rate of decline of the breeding greenfinch population within England has exceeded 7 per cent since the initial epidemic. Although initially chaffinch populations were regionally diminished by the disease, this has not continued. Retrospective analyses of disease surveillance data showed a rapid, widespread emergence of finch trichomonosis across Great Britain in 2005 and we hypothesize that the disease emerged by T. gallinae jumping from columbiforms to passeriforms. Further investigation is required to determine the continuing impact of finch trichomonosis and to develop our understanding of how protozoal diseases jump host species. PMID:22966140

  4. 'They Shall See His Face': Blindness in British India, 1850-1950.

    PubMed

    Nair, Aparna

    2017-04-01

    This paper explores the social, medical, institutional and enumerative histories of blindness in British India from 1850 to 1950. It begins by tracing the contours and causes of blindness using census records, and then outlines how colonial physicians and observers ascribed both infectious aetiologies and social pathologies to blindness. Blindness was often interpreted as the inevitable consequence of South Asian ignorance, superstition and backwardness. This paper also explores the social worlds of the Blind, with a particular focus on the figure of the blind beggar. This paper further interrogates missionary discourse on 'Indian' blindness and outlines how blindness was a metaphor for the perceived civilisational inferiority and religious failings of South Asian peoples. This paper also describes the introduction of institutions for the Blind in addition to the introduction of Braille and Moon technologies.

  5. British participation in the first Solvay Councils on physics

    NASA Astrophysics Data System (ADS)

    Heilbron, J. L.

    2015-09-01

    Analysis of the makeup and contributions of the British contingents to the first two Solvay Councils can elucidate the character of British mathematical physics and its internal dynamics at a critical time in its development. The paper provides this analysis, outlines the process of selection of the participants, parses the meaning of "international" in the Solvay context, and offers an explanation of the differential attendance of the British at the two Councils. Most of those invited to the first refused whereas all but one of those invited to the second accepted. The unusual social and scientific views of Ernest Solvay help to explain this divergence.

  6. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Each lot of substandard pistachios may be reworked to meet aflatoxin or quality requirements. The... reporting. If a lot fails to meet the aflatoxin and/or the quality requirements of this part, a failed lot.... This form must be completed and submitted to the committee each time a lot fails either aflatoxin...

  7. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Each lot of substandard pistachios may be reworked to meet aflatoxin or quality requirements. The... reporting. If a lot fails to meet the aflatoxin and/or the quality requirements of this part, a failed lot.... This form must be completed and submitted to the committee each time a lot fails either aflatoxin...

  8. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Each lot of substandard pistachios may be reworked to meet aflatoxin or quality requirements. The... reporting. If a lot fails to meet the aflatoxin and/or the quality requirements of this part, a failed lot.... This form must be completed and submitted to the committee each time a lot fails either aflatoxin...

  9. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Failed lots/rework procedure. 983.52 Section 983.52..., ARIZONA, AND NEW MEXICO Regulations § 983.52 Failed lots/rework procedure. (a) Substandard pistachios... committee may establish, with the Secretary's approval, appropriate rework procedures. (b) Failed...

  10. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  11. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  12. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  13. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  14. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related...

  15. Rescuing failed oral implants via Wnt activation

    PubMed Central

    Yin, Xing; Li, Jingtao; Chen, Tao; Mouraret, Sylvain; Dhamdhere, Girija; Brunski, John B.; Zou, Shujuan; Helms, Jill A.

    2016-01-01

    Aim Implant osseointegration is not always guaranteed and once fibrous encapsulation occurs clinicians have few options other than implant removal. Our goal was to test whether a WNT protein therapeutic could rescue such failed implants. Material and Methods Titanium implants were placed in over-sized murine oral osteotomies. A lack of primary stability was verified by mechanical testing. Interfacial strains were estimated by finite element modelling and histology coupled with histomorphometry confirmed the lack of peri-implant bone. After fibrous encapsulation was established peri-implant injections of a liposomal formulation of WNT3A protein (L-WNT3A) or liposomal PBS (L-PBS) were then initiated. Quantitative assays were employed to analyse the effects of L-WNT3A treatment. Results Implants in gap-type interfaces exhibited high interfacial strains and no primary stability. After verification of implant failure, L-WNT3A or L-PBS injections were initiated. L-WNT3A induced a rapid, significant increase in Wnt responsiveness in the peri-implant environment, cell proliferation and osteogenic protein expression. The amount of peri-implant bone and bone in contact with the implant were significantly higher in L-WNT3A cases. Conclusions These data demonstrate L-WNT3A can induce peri-implant bone formation even in cases where fibrous encapsulation predominates. PMID:26718012

  16. Cognitive emotion regulation fails the stress test

    PubMed Central

    Raio, Candace M.; Orederu, Temidayo A.; Palazzolo, Laura; Shurick, Ashley A.; Phelps, Elizabeth A.

    2013-01-01

    Cognitive emotion regulation has been widely shown in the laboratory to be an effective way to alter the nature of emotional responses. Despite its success in experimental contexts, however, we often fail to use these strategies in everyday life where stress is pervasive. The successful execution of cognitive regulation relies on intact executive functioning and engagement of the prefrontal cortex, both of which are rapidly impaired by the deleterious effects of stress. Because it is specifically under stressful conditions that we may benefit most from such deliberate forms of emotion regulation, we tested the efficacy of cognitive regulation after stress exposure. Participants first underwent fear-conditioning, where they learned that one stimulus (CS+) predicted an aversive outcome but another predicted a neutral outcome (CS−). Cognitive regulation training directly followed where participants were taught to regulate fear responses to the aversive stimulus. The next day, participants underwent an acute stress induction or a control task before repeating the fear-conditioning task using these newly acquired regulation skills. Skin conductance served as an index of fear arousal, and salivary α-amylase and cortisol concentrations were assayed as neuroendocrine markers of stress response. Although groups showed no differences in fear arousal during initial fear learning, nonstressed participants demonstrated robust fear reduction following regulation training, whereas stressed participants showed no such reduction. Our results suggest that stress markedly impairs the cognitive regulation of emotion and highlights critical limitations of this technique to control affective responses under stress. PMID:23980142

  17. Capital disadvantage: America's failing capital investment system.

    PubMed

    Porter, M E

    1992-01-01

    The U.S. system of allocating investment capital is failing, putting American companies at a serious disadvantage and threatening the long-term growth of the nation's economy. The problem, says Michael Porter, goes beyond the usual formulation of the issue: accusations of "short-termism" by U.S. managers, ineffective corporate governance by directors, or a high cost of capital. The problem involves the external capital allocation system by which capital is provided to companies, as well as the system by which companies allocate capital internally. America's system is marked by fluid capital and a financial focus. Other countries--notably Japan and Germany--have systems with dedicated capital and a focus on corporate position. In global competition, where investment increasingly determines a company's capacity to upgrade and innovate, the U.S. system does not measure up. These conclusions come out of a two-year research project sponsored by the Harvard Business School and the Council on Competitiveness. Porter recommends five far-reaching reforms to make the U.S. system superior to Japan's and Germany's: 1. Improve the present macroeconomic environment. 2. Expand true ownership throughout the system so that directors, managers, employees, and even customers and suppliers hold positions as owners. 3. Align the goals of capital providers, corporations, directors, managers, employees, customers, suppliers, and society. 4. Improve the information used in decision making. 5. Foster more productive modes of interaction and influence among capital providers, corporations, and business units.

  18. Status Review of the Marbled Murrelet (Brachyramphus marmoratus) in Alaska and British Columbia

    DTIC Science & Technology

    2006-01-01

    Burger, University of Victoria, S.A. Hatch, U.S. Geological Survey, V.L. Friesen , Queen’s University, T.P. Birt, Queens University, M.L. Arimitsu, U.S...Kuletz, K.J., Burger, A.E., Hatch, S.A., Friesen , V.L., Birt, T.P. , Arimitsu, M.L., Drew, G.S., Harding, A.M.A., and K.S. Bixler, 2007, Status...British Columbia ........................................................189 Appendix E . Population Trends of the Marbled Murrelet Evident from At-Sea

  19. BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE MAKES BOTH MOLD HALVES INDIVIDUALLY WHICH ARE LATER ROTATED, ASSEMBLED, AND LOWERED TO POURING CONVEYORS BY ASSISTING MACHINES. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  20. SPECIES RICHNESS AND BIODIVERSITY CONSERVATION PRIORITIES IN BRITISH COLUMBIA

    EPA Science Inventory

    Patterns in the geographic distribution of seven species groups were used to identify important areas for conservation in British Columbia, Canada. Potential priority sites for conservation were determined using an integer programming algorithm that maximized the number of speci...

  1. FILLING MOLDS MADE ON THE BRITISH MOLDING MACHINE, AUTOMATIC COPE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FILLING MOLDS MADE ON THE BRITISH MOLDING MACHINE, AUTOMATIC COPE AND DRAG (BMM) FROM MOBILE LADLE. EMPTY BULL LADLE IN FOREGROUND. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  2. Beliefs about Overcoming Psychological Problems among British and Japanese Students.

    ERIC Educational Resources Information Center

    Furnham, Adrian; Ota, Hiromi; Tatsuro, Hosoe; Koyasu, Masuo

    2000-01-01

    Examines the cultural differences among Japanese students, British students, and Japanese students studying in Britain, concerning their beliefs on overcoming five psychological problems: depression, obesity, smoking cessation, agoraphobia, and lack of confidence. (CMK)

  3. Towards Diversification of Secondary Special Education in British Columbia

    ERIC Educational Resources Information Center

    Csapo, Marg

    1978-01-01

    Discussed is the trend in British Columbia, Canada, towards diversification of secondary special education programs, which in the past were restricted to occupational programs that became "dumping grounds" for all types of problem students. (DLS)

  4. A review of catastrophic drainage of moraine-dammed lakes in British Columbia

    NASA Astrophysics Data System (ADS)

    Clague, John J.; Evans, Stephen G.

    2000-12-01

    Moraine-dammed lakes are common in the high mountains of British Columbia. Most of these lakes formed when valley and cirque glaciers retreated from advanced positions achieved during the Little Ice Age. Many moraine dams in British Columbia are susceptible to failure because they are steep-sided, have relatively low width-to-height ratios, comprise loose, poorly sorted sediment, and may contain ice cores or interstitial ice. In addition, the lakes commonly are bordered by steep slopes that are prone to snow and ice avalanches and rockfalls. Moraine dams generally fail by overtopping and incision. The triggering event may be a heavy rainstorm, or an avalanche or rockfall that generates waves that overtop the dam. The dam can also be overtopped by an influx of water caused by sudden drainage of an upstream ice-dammed lake (jökulhlaup). Melting of moraine ice cores and piping are other possible failure mechanisms. Failures of moraine dams in British Columbia produce destructive floods orders of magnitude larger than normal streamflows. Most outburst floods are characterized by an exponential increase in discharge, followed by an abrupt drop to background levels when the water supply is exhausted. Peak discharges are controlled by dam characteristics, the volume of water in the reservoir, failure mechanisms, and downstream topography and sediment availability. For the same potential energy at the dam site, floods from moraine-dammed lakes have higher peak discharges than floods from glacier-dammed lakes. The floodwaters may mobilize large amounts of sediment as they travel down steep valleys, producing highly mobile debris flows. Such flows have larger discharges and greater destructive impact than the floods from which they form. Moraine dam failures in British Columbia and elsewhere are most frequent following extended periods of cool climate when large lateral and end moraines are built. A period of protracted warming is required to trap lakes behind moraines and

  5. Revision of failed humeral head resurfacing arthroplasty

    PubMed Central

    Streubel, Philipp N.; Simone, Juan P.; Cofield, Robert H.; Sperling, John W.

    2016-01-01

    Purpose: The purpose of this study is to assess the outcomes of a consecutive series of patients who underwent revision surgery after humeral head resurfacing (HHR). Our joint registry was queried for all patients who underwent revision arthroplasty for failed HHR at our institution from 2005 to 2010. Eleven consecutive patients (average age 54 years; range 38-69 years) that underwent revision of 11 resurfacing arthroplasties were identified. The primary indication for resurfacing had been osteoarthritis in six, glenoid dysplasia in two, a chondral lesion in two, and postinstability arthropathy in one patient. The indication for revision was pain in 10 and infection in one patient. Seven patients had undergone an average of 1.9 surgeries prior to resurfacing (range 1-3). Materials and Methods: All patients were revised to stemmed arthroplasties, including one hemiarthroplasty, two reverse, and eight anatomic total shoulder arthroplasties at a mean 33 months after primary resurfacing (range 10-131 months). A deltopectoral approach was used in seven patients; four patients required an anteromedial approach due to severe scarring. Subscapularis attenuation was found in four cases, two of which required reverse total shoulder arthroplasty. Bone grafting was required in one glenoid and three humeri. Results: At a mean follow-up of 3.5 years (range 1.6-6.9 years), modified Neer score was rated as satisfactory in five patients and unsatisfactory in six. Abduction and external rotation improved from 73° to 88° (P = 0.32) and from 23° to 32° (P = 0.28) respectively. Reoperation was required in two patients, including one hematoma and one revision for instability. Conclusion: Outcomes of revision of HHR arthroplasty in this cohort did not improve upon those reported for revision of stemmed humeral implants. A comparative study would be required to allow for definitive conclusions to be made. PMID:26980986

  6. British variable star associations, 1848-1908

    NASA Astrophysics Data System (ADS)

    Toone, J.

    2010-06-01

    The study of variable stars lagged some distance behind solar system, positional (double star) and deep sky research until the middle part of the 19th century. Then, following F. W. A. Argelander's pioneering work in the 1840s, there was a striking increase in variable star research, particularly in Europe. The transformation was to such an extent that in the second half of the 19th century there were three attempts at forming variable star associations within Great Britain. The first in 1863 was the ASOVS, which never got off the ground. The second in 1883 was the LAS VSS, which was successfully launched but had somewhat limited achievements. The third launched in 1890 was the BAA VSS which was eventually both a resounding and lasting success. This paper is an outline history of these three associations up to a position of one hundred years ago (1908). [A summary version of this paper was presented at the joint meeting of the American Association of Variable Star Observers (AAVSO) and British Astronomical Association Variable Star Section (BAA VSS) held at Cambridge, UK, on 2008 April 11.

  7. Utopianism in the British evolutionary synthesis.

    PubMed

    Esposito, Maurizio

    2011-03-01

    In this paper I propose a new interpretation of the British evolutionary synthesis. The synthetic work of J. B. S. Haldane, R. A. Fisher and J. S. Huxley was characterized by both an integration of Mendelism and Darwinism and the unification of different biological subdisciplines within a coherent framework. But it must also be seen as a bold and synthetic Darwinian program in which the biosciences served as a utopian blueprint for the progress of civilization. Describing the futuristic visions of these three scientists in their synthetic heydays, I show that, despite a number of important divergences, their biopolitical ideals could be biased toward a controlled and regimented utopian society. Their common ideals entailed a social order where liberal and democratic principles were partially or totally suspended in favor of bioscientific control and planning for the future. Finally, I will argue that the original redefinition of Darwinism that modern synthesizers proposed is a significant historical example of how Darwinism has been used and adapted in different contexts. The lesson I draw from this account is a venerable one: that, whenever we wish to define Darwinism, we need to recognize not only its scientific content and achievements but expose the other traditions and ideologies it may have supported.

  8. ASPIRE - the first British student rocket programme

    NASA Astrophysics Data System (ADS)

    Baker, Adam M.; Murray, J.; Osborne, R.; Macfarlane, J.

    ASPIRE is the first British programme aiming to create and develop a small scale, hybrid engine powered launch vehicle. The project is also unique because it is a wholly amateur effort, volunteer team members having little or no professional experience in launch vehicle design, manufacture and operations; and being a mix of students and young professionals. Participants have the opportunity to develop their experience in the engineering/scientific, operational and management areas which ASPIRE encompasses. This experience will then be validated through the launching of a series of test vehicles, culminating in a demonstration of the orbital insertion of a payload by the year 2000. ASPIRE aims to eventually return an independent orbital launch capability to Britain, for the first time since 1971. This paper outlines the technical details of the ASPIRE rockets, including: airframe design and manufacture, hybrid motor design and testing, avionics development, guidance and recovery techniques, range safety practise and marketing and fund-raising. It will also cover the organisation and ethos of the programme in general. A timeline for the ASPIRE programme will be detailed, from the original ASPIRE 1 construction and launch in 1991/1992, evolving through the current series of ASPIRE Development Vehicles (ADVs), to ASPIRE 2 and 3, where the hybrid motor and other engineering subsystems are to be integrated on an increasing scale. The proposed union of an ASPIRE 3 vehicle with an Australian AUSROC launcher to achieve the 2000 orbital goal will also be covered.

  9. Socialism and the British National Health Service.

    PubMed

    Powell, M

    1997-09-01

    This paper examines some of the key characteristics of a socialist health care system using the example of the British National Health Service (NHS). It has been claimed that the NHS has socialist principles, and represents an island of socialism in a capitalist sea. However, using historical analysis, this paper argues that while the NHS claims some socialist ends, they could never be fully achieved because of the lack of socialist means. The socialist mechanisms which were associated with earlier plans for a national health service such as salaried service, health centres, elected health authorities and divorcing private practice from the public service were discarded in negotiation. Moreover, even these would have achieved socialism merely in the sense of distributing health care, without any deeper transformation associated with doctor-patient relationships and prevention. In short, the NHS is more correctly seen as nationalised rather than socialised medicine, achieving the first three levels of a socialist health service identified here. It can be said to have socialist principles in the limited distributional sense and has some socialist means to achieve these. However, it lacks the stronger means to fully achieve its distributional goals, and is very distant from the third level of a radical transformation of health care.

  10. The Planetary Consciousness of British Travel Writers

    NASA Astrophysics Data System (ADS)

    Henry, H.

    2013-04-01

    Global travel, advanced in the early 20th century by trains, automobiles, and airplanes, transformed modernist thought and experience. Stephen Kern has commented that in the modern period “a series of sweeping changes in technology and culture created distinctive new modes of thinking about and experiencing of time and space. Technological innovations including the telephone, wireless telegraph, x-ray, cinema, bicycle, automobile, and airplane established the material foundation for this reorientation.” (1983, pp. 1-2). Emerging travel technologies not only hurled passengers through multiple time zones in a day but also brought to the fore a global awareness regarding Earth as a globe in space and one's position on it. As early as 1909, while traveling in Florence, Virginia Woolf had noted in her diary, “It is strange how one begins to hold a globe in one's head: I can travel from Florence to Fitzroy Square on solid land all the time” (1984, p. 399). This paper traces the ways modernist British travel writers challenged England's geographical and geopolitical imagination at the turn of the 20th century through their travel narratives.

  11. Gambian-British and Nigerian-British Children's and Families' Experiences of Migration "Back" to West Africa. Research Briefing No. 13

    ERIC Educational Resources Information Center

    Roberts-Holmes, Guy

    2013-01-01

    This research looks at the factors motivating Gambian-British and Nigerian-British parents to send their children "back" to West Africa and what this means for parents, children and families on both continents.

  12. Associations between socioeconomic, parental and home environment factors and fruit and vegetable consumption of children in grades five and six in British Columbia, Canada

    PubMed Central

    2014-01-01

    Background Regular fruit and vegetable (FV) consumption has been associated with reduced chronic disease risk. Evidence from adults shows a social gradient in FV consumption. Evidence from pre-adolescent children varies and there is little Canadian data. This study assessed the FV intake of school children in British Columbia (BC), Canada to determine whether socio-economic status (SES), parental and the home environment factors were related to FV consumption. Methods As part of the BC School Fruit and Vegetable Nutrition Program, 773 British Columbia fifth-and sixth-grade school children (Mean age 11.3 years; range 10.3-12.5) and their parents were surveyed to determine FV consumption and overall dietary intake. Students completed a web-based 24-hour dietary food recall, and a student measure of socio-economic status (The Family Affluence Scale). Parents completed a self-administered survey about their education, income, home environment and perceptions of their neighbourhood and children’s eating habits. Correlations and multiple regression analyses were used to examine the association between SES, parental and home environment factors and FV consumption. Results Approximately 85.8% of children in this study failed to meet minimum Canadian guidelines for FV intake (6 servings). Parent income and education were not significantly associated with child FV consumption but were associated with each other, child-reported family affluence, neighbourhood environment, access to FV, and eating at the table or in front of the television. Significant positive associations were found between FV consumption and child-reported family affluence, meal-time habits, neighbourhood environment and parent perceptions of the healthiness of their child’s diet; however, these correlations were weak (ranging from .089-.115). Multiple regression analysis showed that only child-reported family affluence significantly predicted FV consumption (std-β = 0.096 95% CI = 0.01 to 0

  13. Transforming family practice in British Columbia

    PubMed Central

    Cavers, William J.R.; Tregillus, Valerie H.F.; Micco, Angela; Hollander, Marcus J.

    2010-01-01

    ABSTRACT OBJECTIVE To describe a new approach to primary care reform developed in British Columbia (BC) under the leadership of the General Practice Services Committee (GPSC). COMPOSITION OF THE COMMITTEE The GPSC is a joint committee of the BC Ministry of Health Services, the BC Medical Association, and the Society of General Practitioners of BC. Representatives of BC’s health authorities also attend as guests. METHOD This paper is based on the 2008–2009 annual report of the GPSC. It summarizes the history and main activities of the GPSC. REPORT The GPSC is currently supporting a number of key activities to transform primary care in BC. These activities include the Full Service Family Practice Incentive Program, which provides incentive payments to promote enhanced primary care; the Practice Support Program, which provides family physicians and their medical office assistants with various practical evidence-based strategies and tools for managing practice enhancement; the Family Physicians for BC Program to develop family practices in areas of identified need; the Shared Care Committee, which supports and enables the determination of appropriate scopes of practice among GPs, specialists, and other health care professionals; the Divisions of Family Practice, which are designed to facilitate interactions among family doctors and between doctors and their respective health authorities; and the Community Healthcare and Resource Directory, a Web-based resource to help health care providers find appropriate mental health resources. CONCLUSION Early results indicate that the GPSC’s initiatives are enhancing the delivery of primary care services in BC. PMID:21156899

  14. Trace nutrients. 4. Iodine in British food.

    PubMed

    Wenlock, R W; Buss, D H; Moxon, R E; Bunton, N G

    1982-05-01

    1. The amounts of iodine in nationally representative samples of prepared and cooked groups of foods and in a wide variety of individual foods and food products were determined colorimetrically. The amounts of erythrosine, a red food colour containing 577 mg I/g were also determined in selected foods and diets by high-performance liquid chromatography. 2. The average British diet was calculated to provide 323 micrograms I/d but only 255 micrograms if two fruit samples containing large amounts of glacé cherries were discounted. Of the total, 92 micrograms was derived from liquid milk. Meat and meat products provided 36 micrograms and cereal products 31 micrograms, but fresh fruits and sugars, vegetables and beverages provided little I. Fish and fish products, though rich in I, contributed only 5% to the total intake. 3. Milk was the most variable as well as the most important individual source of I. Summer milk samples contained 70 micrograms/kg and winter milk 370 micrograms/kg on average. Milk products, including butter and cheese, and eggs were also rich in I. 4. Some processed foods contained erythrosine, particularly glacé cherries and some pink or red confectionery items, biscuits, cherry cake, canned strawberries and luncheon meat. However, none of these are major foods in the average household diet and erythrosine would therefore contribute little more than 10 micrograms I/d to most diets. 5. The average daily intake of I was lower than in similar similar studies in the USA, but was twice the provisional UK recommended intake. This study provides no evidence that I intakes in the UK could be too low or too high for health.U

  15. Interior's Climate Science Centers: Focus or Fail

    NASA Astrophysics Data System (ADS)

    Udall, B.

    2012-12-01

    After a whirlwind two years of impressive and critical infrastructure building, the Department of Interior's Climate Science Centers are now in a position to either succeed or fail. The CSCs have a number of difficult structural problems including too many constituencies relative to the available resources, an uneasy relationship among many of the constituencies including the DOI agencies themselves, a need to do science in a new, difficult and non-traditional way, and a short timeframe to produce useful products. The CSCs have built a broad and impressive network of scientists and stakeholders. These entities include science providers of the universities and the USGS, and decision makers from the states, tribes, DOI land managers and other federal agencies and NGOs. Rather than try to support all of these constituencies the CSCs would be better served by refocusing on a core mission of supporting DOI climate related decision making. The CSCs were designed to service the climate science needs of DOI agencies, many of which lost their scientific capabilities in the 1990s due to a well-intentioned but ultimately harmful re-organization at DOI involving the now defunct National Biological Survey. Many of these agencies would like to have their own scientists, have an uneasy relationship with the nominal DOI science provider, the USGS, and don't communicate effectively among themselves. The CSCs must not succumb to pursuing science in either the traditional mode of the USGS or in the traditional mode of the universities, or worse, both of them. These scientific partners will need to be flexible, learn how to collaborate and should expect to see fewer resources. Useful CSC processes and outputs should start with the recommendations of the 2009 NRC Report Informing Decisions in a Changing Climate: (1) begin with users' needs; (2) give priority to process over products; (3) link information producers and users; (4) build connections across disciplines and organizations

  16. Smoking and musculoskeletal disorders: findings from a British national survey

    PubMed Central

    Palmer, K; Syddall, H; Cooper, C; Coggon, D

    2003-01-01

    Objectives: To explore the relation between smoking habits and regional pain in the general population. Methods: A questionnaire was mailed to 21 201 adults, aged 16–64 years, selected at random from the registers of 34 British general practices, and to 993 members of the armed services, randomly selected from pay records. Questions were asked about pain in the low back, neck, and upper and lower limbs during the past 12 months; smoking habits; physical activities at work; headaches; and tiredness or stress. Associations were examined by logistic regression and expressed as prevalence ratios (PRs). Results: Questionnaires were completed by 12 907 (58%) subjects, including 6513 who had smoked at some time, among whom 3184 were current smokers. Smoking habits were related to age, social class, report of headaches, tiredness or stress, and manual activities at work. After adjustment for potential confounders, current and ex-smokers had higher risks than lifetime non-smokers for pain at all of the sites considered. This was especially so for pain reported as preventing normal activities (with PRs up to 1.6 in current v never smokers). Similar associations were found in both sexes, and when analysis was restricted to non-manual workers. Conclusions: There is an association between smoking and report of regional pain, which is apparent even in ex-smokers. This could arise from a pharmacological effect of tobacco smoke (for example, on neurological processing of sensory information or nutrition of peripheral tissues); another possibility is that people with a low threshold for reporting pain and disability are more likely to take up and continue smoking. PMID:12480666

  17. Temporal genetic variation of the red fox, Vulpes vulpes, across western Europe and the British Isles

    PubMed Central

    Edwards, Ceiridwen J.; Soulsbury, Carl D.; Statham, Mark J.; Ho, Simon Y.W.; Wall, Dave; Dolf, Gaudenz; Iossa, Graziella; Baker, Phillip J.; Harris, Stephen; Sacks, Benjamin N.; Bradley, Daniel G.

    2012-01-01

    Quaternary climatic fluctuations have had profound effects on the phylogeographic structure of many species. Classically, species were thought to have become isolated in peninsular refugia, but there is limited evidence that large, non-polar species survived outside traditional refugial areas. We examined the phylogeographic structure of the red fox (Vulpes vulpes), a species that shows high ecological adaptability in the western Palaearctic region. We compared mitochondrial DNA sequences (cytochrome b and control region) from 399 modern and 31 ancient individuals from across Europe. Our objective was to test whether red foxes colonised the British Isles from mainland Europe in the late Pleistocene, or whether there is evidence that they persisted in the region through the Last Glacial Maximum. We found red foxes to show a high degree of phylogeographic structuring across Europe and, consistent with palaeontological and ancient DNA evidence, confirmed via phylogenetic indicators that red foxes were persistent in areas outside peninsular refugia during the last ice age. Bayesian analyses and tests of neutrality indicated population expansion. We conclude that there is evidence that red foxes from the British Isles derived from central European populations that became isolated after the closure of the landbridge with Europe. PMID:24068852

  18. Temporal genetic variation of the red fox, Vulpes vulpes, across western Europe and the British Isles.

    PubMed

    Edwards, Ceiridwen J; Soulsbury, Carl D; Statham, Mark J; Ho, Simon Y W; Wall, Dave; Dolf, Gaudenz; Iossa, Graziella; Baker, Phillip J; Harris, Stephen; Sacks, Benjamin N; Bradley, Daniel G

    2012-12-04

    Quaternary climatic fluctuations have had profound effects on the phylogeographic structure of many species. Classically, species were thought to have become isolated in peninsular refugia, but there is limited evidence that large, non-polar species survived outside traditional refugial areas. We examined the phylogeographic structure of the red fox (Vulpes vulpes), a species that shows high ecological adaptability in the western Palaearctic region. We compared mitochondrial DNA sequences (cytochrome b and control region) from 399 modern and 31 ancient individuals from across Europe. Our objective was to test whether red foxes colonised the British Isles from mainland Europe in the late Pleistocene, or whether there is evidence that they persisted in the region through the Last Glacial Maximum. We found red foxes to show a high degree of phylogeographic structuring across Europe and, consistent with palaeontological and ancient DNA evidence, confirmed via phylogenetic indicators that red foxes were persistent in areas outside peninsular refugia during the last ice age. Bayesian analyses and tests of neutrality indicated population expansion. We conclude that there is evidence that red foxes from the British Isles derived from central European populations that became isolated after the closure of the landbridge with Europe.

  19. An examination of social capital and social disorganisation in neighbourhoods in the British household panel study.

    PubMed

    McCulloch, Andrew

    2003-04-01

    Recent developments in social science research suggest that social environmental factors may be important for explaining community variations in health. We investigate the structural sources of two mechanisms that produce community variations in health. Using survey data collected from a representative cross-section of British households we examine variations in neighbourhood social capital and neighbourhood social disorganisation across a sample of British neighbourhoods. Adjusting for respondent's attributes, we assess the effects of neighbourhood characteristics measured by the 1991 census in Britain. The results show that concentrated affluence, residential instability and ethnic heterogeneity predict social capital for women. Population density is the only neighbourhood characteristic to predict social capital for men. For both men and women concentrated disadvantage and population density are associated with social disorganisation. Residential instability is additionally associated with social disorganisation for women. For women it was found that neighbourhood characteristics interact with individual social class in accounting for variations in social capital, the effects of neighbourhood characteristics being larger for those in professional and managerial and skilled non-manual occupations. The results show that neighbourhood structural characteristics influence social organisation processes. This helps establish a link between the structural characteristics of neighbourhoods and individual health outcomes.

  20. Temporal genetic variation of the red fox, Vulpes vulpes, across western Europe and the British Isles

    NASA Astrophysics Data System (ADS)

    Edwards, Ceiridwen J.; Soulsbury, Carl D.; Statham, Mark J.; Ho, Simon Y. W.; Wall, Dave; Dolf, Gaudenz; Iossa, Graziella; Baker, Phillip J.; Harris, Stephen; Sacks, Benjamin N.; Bradley, Daniel G.

    2012-12-01

    Quaternary climatic fluctuations have had profound effects on the phylogeographic structure of many species. Classically, species were thought to have become isolated in peninsular refugia, but there is limited evidence that large, non-polar species survived outside traditional refugial areas. We examined the phylogeographic structure of the red fox (Vulpes vulpes), a species that shows high ecological adaptability in the western Palaearctic region. We compared mitochondrial DNA sequences (cytochrome b and control region) from 399 modern and 31 ancient individuals from across Europe. Our objective was to test whether red foxes colonised the British Isles from mainland Europe in the late Pleistocene, or whether there is evidence that they persisted in the region through the Last Glacial Maximum. We found red foxes to show a high degree of phylogeographic structuring across Europe and, consistent with palaeontological and ancient DNA evidence, confirmed via phylogenetic indicators that red foxes were persistent in areas outside peninsular refugia during the last ice age. Bayesian analyses and tests of neutrality indicated population expansion. We conclude that there is evidence that red foxes from the British Isles derived from central European populations that became isolated after the closure of the landbridge with Europe.

  1. British sociology and public intellectuals: consumer society and imperial decline.

    PubMed

    Turner, Bryan S

    2006-06-01

    The following is the lecture given for the BJS 2005 Public Sociology Debate given at the London School of Economics and Political Science on ll October 2005. This lecture on the character of British sociology provides a pretext for a more general inquiry into public intellectual life in postwar Britain. The argument put forward falls into several distinctive sections. First, British social science has depended heavily on the migration of intellectuals, especially Jewish intellectuals who were refugees from fascism. Second, intellectual innovation requires massive, disruptive, violent change. Third, British sociology did nevertheless give rise to a distinctive tradition of social criticism in which one can argue there were (typically home-grown) public intellectuals. The main theme of their social criticism was to consider the constraining and divisive impact of social class, race and gender on the enjoyment of expanding social citizenship. Fourth, postwar British sociology came to be dominated by the analysis of an affluent consumer society. Finally, the main failure of British sociology in this postwar period was the absence of any sustained, macro-sociological analysis of the historical decline of Britain as a world power in the twentieth century.

  2. The British Geological Survey's 'Slope Dynamics' Project

    NASA Astrophysics Data System (ADS)

    Hobbs, Peter; Foster, Claire; Pearson, Stephen; Jones, Lee; Pennington, Catherine; Jenkins, Gareth; Gibson, Andrew; Cooper, Anthony; Freeborough, Katherine

    2010-05-01

    The aim of the British Geological Survey (BGS)'s ‘Slope Dynamics' project is to provide observational data to slope stability modelling and zoning based on factors of safety obtained from a combination of geotechnical, geomorphological and oceanographic models. The project has been monitoring since 2001 the progress of terrestrial and coastal landslides within 'soft rock' formations in the UK. Recently, field observatories have been set up to allow a variety of methods, some traditional and others novel, to be applied to actively unstable natural slopes in order to achieve a thorough understanding of the substrata, the mass movement processes within them and their relationship to the environment and environmental change. Monitoring has been carried out at six or twelve monthly intervals at test sites on the east coast of England (Holderness and Norfolk) and at Hollin Hill in North Yorkshire. A key part of the project makes use of innovative terrestrial LiDAR methods to produce repeated accurate 3-D models of the ground surface, which then enable ‘change models' of landslide movements to be determined. This work was started in 2001 and is continuing. The BGS currently has two Riegl terrestrial laser scanners: the long-range LPM-i800HA and the very-long-range LPM-2K; the former being equipped with a digital camera. The multiple scans are positioned in the national grid co-ordinate system using high resolution dGPS. Together, these allow accurate observations to be made in remote and exposed locations without the need for potentially dangerous direct access to the steeper more unstable slopes. The coastal test sites, which have exhibited recession rates of between 2m and 9m per year, allow rapid changes to be monitored. Inland active landslides are less common but more suited to instrumentation and long-term monitoring. Results to date have revealed the relationships between landslide style and geology, and also the patterns and time scales of characteristic

  3. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Failed lots/rework procedure. 983.152 Section 983.152..., ARIZONA, AND NEW MEXICO Rules and Regulations § 983.152 Failed lots/rework procedure. (a) Inshell rework procedure for aflatoxin. If inshell rework is selected as a remedy to meet the aflatoxin regulations of...

  4. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Reconditioning failing quality peanuts. 996.50 Section... QUALITY AND HANDLING STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Quality and Handling Standards § 996.50 Reconditioning failing quality peanuts. (a) Lots of peanuts which have not...

  5. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Reconditioning failing quality peanuts. 996.50 Section... QUALITY AND HANDLING STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Quality and Handling Standards § 996.50 Reconditioning failing quality peanuts. (a) Lots of peanuts which have not...

  6. 75 FR 76321 - Source of Income From Qualified Fails Charges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BJ78 Source of Income From Qualified Fails Charges AGENCY... Internal Revenue Code. These regulations set forth the source of income attributable to qualified fails... Subjects in 26 CFR Part 1 Income taxes, Reporting and recordkeeping requirements. Proposed Amendment to...

  7. 75 FR 76262 - Source of Income From Qualified Fails Charges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BJ85 Source of Income From Qualified Fails Charges AGENCY... temporary regulations which set forth the source of income attributable to qualified fails charges. The.... source income of foreign persons that is not effectively connected with the conduct of a trade...

  8. 77 FR 9846 - Source of Income From Qualified Fails Charges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BJ78 Source of Income From Qualified Fails Charges AGENCY.... SUMMARY: This document contains final regulations that prescribe the source of income received on a... income from a qualified fails charge is generally determined by reference to the residence of...

  9. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Reconditioning failing quality peanuts. 996.50 Section... QUALITY AND HANDLING STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Quality and Handling Standards § 996.50 Reconditioning failing quality peanuts. (a) Lots of peanuts which have not...

  10. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Reconditioning failing quality peanuts. 996.50 Section... QUALITY AND HANDLING STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Quality and Handling Standards § 996.50 Reconditioning failing quality peanuts. (a) Lots of peanuts which have not...

  11. 7 CFR 996.50 - Reconditioning failing quality peanuts.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Reconditioning failing quality peanuts. 996.50 Section... QUALITY AND HANDLING STANDARDS FOR DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Quality and Handling Standards § 996.50 Reconditioning failing quality peanuts. (a) Lots of peanuts which have not...

  12. Erika's Stories: Literacy Solutions for a Failing Middle School Student

    ERIC Educational Resources Information Center

    Ma'ayan, Hadar Dubowsky

    2010-01-01

    Erika was a failing student at a large urban public middle school. She was poor, Hispanic, bilingual, and had repeated fourth grade. She scored low on her standardized tests and was failing several subject areas. In class, Erika was a student who sat silently with her head on her desk, and rarely turned in any of her assignments. She was a…

  13. British Gas/Lurgi Slagging Gasifier a springboard into synfuels

    SciTech Connect

    Sharman, R.B.; Lacey, J.A.; Scott, J.E.

    1981-01-01

    The most developed and widely used fixed bed pressure gasification systems are based on the Lurgi Gasification Process. The British Gas/Lurgi Slagging Gasifier results from the joing together of British Gas Corporation and Lurgi Company technology. The British Gas Slagging Gasification technology offers significant advantages over dry bottom Lurgi and other fixed bed gasification systems. The slagging gasifier has more advantages than disadvantages when compared with entrained flow gasifiers and these advantages are sufficient to give it an economic advnatage in most process situations. The processing of crude Slagging Gasifier gas and the multifarious uses of the resulting clean gas in the chemicals, power generation and fuel gas fields are described. The environmental impact of the process is also discussed and plans for commercialization are considered. 21 refs.

  14. US utilities show interest in British coalgas process

    SciTech Connect

    Smock, R.W.

    1981-04-01

    A British version of technology to produce coal gas by the slagging Lurgi process is considered the best method for commercialization in the US because of its successful operation as a demonstration sine 1974. The British Gas Corp. system guarantees gasification of up to 350 tons a day. A seven-year lead time is estimated for transferring and putting the technology on line. The Electric Power Research Institute is looking at two other processes besides the slagging Lurgi process, but the Administration's cancellation of synfuels subsidies jeopardizes some planned projects. Indications that the British process will be competitive without Federal assistance has attracted the interest of US investors. Performance data on the Lurgi process is summarized in three tables. (DCK)

  15. British Columbia: improving retention and recruitment in smaller communities.

    PubMed

    Healey-Ogden, Marion; Wejr, Patricia; Farrow, Catherine

    2012-03-01

    This pilot project involved the application, in Canada, of the innovative 80/20 staffing model to a hospital in a small rural setting. The model provides the voluntary participants with 20% of their salaried time off from direct patient care in order to pursue various types of professional development activities. The project, overseen by a steering committee, lasted from June 2009 to February 2010 and involved 14 nurses on the pediatric unit of Royal Inland Hospital in Kamloops, British Columbia. It entailed a collaborative partnership of the British Columbia Nurses' Union, Interior Health Authority, Thompson Rivers University and the British Columbia Ministry of Health, and aimed to demonstrate how professional development opportunities can improve recruitment and retention of nurses, quality of work life and quality of patient care.

  16. On the impartiality of early British clinical trials.

    PubMed

    Teira, David

    2013-09-01

    Did the impartiality of clinical trials play any role in their acceptance as regulatory standards for the safety and efficacy of drugs? According to the standard account of early British trials in the 1930s and 1940s, their impartiality was just rhetorical: the public demanded fair tests and statistical devices such as randomization created an appearance of neutrality. In fact, the design of the experiment was difficult to understand and the British authorities took advantage of it to promote their own particular interests. I claim that this account is based on a poorly defined concept of experimental fairness (derived from T. Porter's ideas). I present an alternative approach in which a test would be impartial if it incorporates warrants of non-manipulability. With this concept, I reconstruct the history of British trials showing that they were indeed fair and this fairness played a role in their acceptance as regulatory yardsticks.

  17. ["The demon that turned into worms": the translation of public health in the British Caribbean, 1914-1920].

    PubMed

    Palmer, Steven

    2006-01-01

    The earliest programs of the Rockefeller Foundation's International Health Commission - IHC were pilot projects for the treatment of hookworm disease in the British colonies of British Guiana and Trinidad. These pioneering ventures into international health have often been portrayed as governed by rigid biomedical principles. In contrast to this view, the article emphasizes the degree to which the exigencies of a public health project that sought to make biomedicine intelligible within the medical systems of subject populations combined with the knowledge of local IHC staff members of Indo-Caribbean descent to generate some fascinating experiments in ethno-medical translation. One term in particular "The Demon that Turned into Worms" is focused on to show how these efforts at medical translation may have legitimized and promoted medical pluralism.

  18. Morbidity associated with failed vaginal birth after cesarean section.

    PubMed

    Oboro, Victor; Adewunmi, Adeniyi; Ande, Anibaba; Olagbuji, Biodun; Ezeanochie, Michael; Oyeniran, Ayodeji

    2010-09-01

    We investigated morbidity and factors associated with failed vaginal birth after cesarean delivery (VBAC). In a retrospective cohort study maternal and neonatal outcomes of women who underwent VBAC in three Nigerian University Teaching Hospitals were reviewed. Univariate, followed by multivariate analyses, were conducted. VBAC was successful in 683 of 1,013 women (67.4%), whereas 330 (32.6%) had failed VBAC. Failed VBAC was associated with higher incidence of chorioamnionitis, postpartum hemorrhage, blood transfusion, uterine rupture, hysterectomy, and composite major neonatal morbidities. Younger age, lack of previous vaginal delivery, induction of labor and fetal weight >4,000 g were risk factors for failed VBAC. A majority of women who try VBAC achieve a vaginal delivery. Failed VBAC is associated with increased maternal and neonatal morbidity and is somewhat predictable.

  19. Simulating fail-stop in asynchronous distributed systems

    NASA Technical Reports Server (NTRS)

    Sabel, Laura; Marzullo, Keith

    1994-01-01

    The fail-stop failure model appears frequently in the distributed systems literature. However, in an asynchronous distributed system, the fail-stop model cannot be implemented. In particular, it is impossible to reliably detect crash failures in an asynchronous system. In this paper, we show that it is possible to specify and implement a failure model that is indistinguishable from the fail-stop model from the point of view of any process within an asynchronous system. We give necessary conditions for a failure model to be indistinguishable from the fail-stop model, and derive lower bounds on the amount of process replication needed to implement such a failure model. We present a simple one-round protocol for implementing one such failure model, which we call simulated fail-stop.

  20. A Failing Mission in Afghanistan: Salvation is Possible

    DTIC Science & Technology

    2010-05-13

    8217Iii,/ ( Date: -.v.,.,._,-’-""-+--=--"’-+= Oral Defense Committee Member: Dr. Bradford A. Wineman , Associate Professor of Military History...the process, he gave me a chance and guided my efforts to deliver a coherent document. I would also like to thank Dr. Bradford Wineman for his...surface over military contributions of partners 2007 Jan British royal Marines begin Operation Volcano , followed by Operation Achilles July U.S

  1. Military Interventions in Sierra Leone: Lessons from a Failed State

    DTIC Science & Technology

    2008-01-01

    British, French, Dutch, and Danish traders also landed in Africa. They became interested in the gold, cattle, salt, cloth, palm oil and rice of Sierra...colony was relatively peaceful. The economy thrived during the mid 20th century with large exports of diamonds, palm kernels , coffee, cocoa, and...gold, oil , iron ore, rutile, baux­ ite, and titanium. The economy consists of agriculture, exportation of raw materials and light local industry

  2. Childhood Cancer Incidence in British Indians & Whites in Leicester, 1996–2008

    PubMed Central

    Sayeed, Shameq; Barnes, Isobel; Cairns, Benjamin J.; Finlayson, Alexander; Ali, Raghib

    2013-01-01

    Background South Asians in England have an increased risk of childhood cancer but incidence by their individual ethnicities using self-assigned ethnicity is unknown. Our objective was to compare the incidence of childhood cancer in British Indians and Whites in Leicester, which has virtually complete, self-assigned, ethnicity data and the largest population of Indians in England. Methods We obtained data on all cancer registrations from 1996 to 2008 for Leicester with ethnicity obtained by linkage to the Hospital Episodes Statistics database. Age-standardised incidence rates were calculated for childhood cancers in Indians and Whites as well as rate ratios, adjusted for age. Results There were 33 cancers registered among Indian children and 39 among White children. The incidence rate for Indians was greater compared to Whites for all cancers combined (RR 1.82 (95% CI 1.14 to 2.89); p = 0.01), with some evidence of increased risk of leukaemia (RR 2.20 (0.95 to 5.07); p = 0.07), lymphoma (RR 3.96 (0.99 to 15.84); p = 0.04) and central nervous system tumours (RR 2.70 (1.00 to 7.26); p = 0.05). Rates were also higher in British Indian children compared to children in India. Conclusions British Indian children in Leicester had an increased risk of developing cancer compared to White children, largely due to a higher incidence of central nervous system and haematological malignancies. PMID:23613964

  3. Oral and pharyngeal cancer: knowledge and opinions of dentists in British Columbia and Nova Scotia.

    PubMed

    Clovis, Joanne B; Horowitz, Alice M; Poel, Dale H

    2002-01-01

    Oral and pharyngeal cancers are largely preventable and can be successfully treated when diagnosed at an early stage. Dentists in British Columbia and Nova Scotia were surveyed regarding their knowledge and opinions about oral and pharyngeal cancer. In February 1998 a pretested 41-item survey was mailed to a random sample of dentists in British Columbia and the population of dentists in Nova Scotia. A reminder postcard and one additional mailing were sent to nonrespondents. Of the 670 dentists supplying usable responses (response rate 55.2%) only 56.7% agreed that their knowledge of the subject was current. Most dentists correctly identified tobacco use (99.4%) and alcohol use (90.4%) as risk factors, but fewer correctly identified factors such as the use of spicy foods (57.0%) and poor oral hygiene (46.3%) as not being risk factors. Only 42.5% identified both erythroplakia and leukoplakia, in that order, as the conditions most likely associated with oral cancer. Indices of risk and diagnostic knowledge were constructed by summing the number of correct responses to items in each domain. On 16 risk factors the mean correct score was 9.2, and on 14 diagnostic procedures the mean correct score was 10.0. Only 38.5% of dentists had consistent levels of knowledge on both indices. Differences between the provinces were statistically significant (p < 0.01) for only 2 knowledge items. About three-quarters of all dentists (77.0%) were interested in taking continuing education courses. Dentists in British Columbia and Nova Scotia could benefit from undergraduate and continuing education courses to increase their knowledge of risk and diagnostic factors for oral cancer.

  4. Oral and pharyngeal cancer: practices and opinions of dentists in British Columbia and Nova Scotia.

    PubMed

    Clovis, Joanne B; Horowitz, Alice M; Poel, Dale H

    2002-01-01

    Oral and pharyngeal cancers are associated with high mortality rates, a situation usually attributed to late-stage diagnosis. Dentists in British Columbia and Nova Scotia were surveyed regarding their practices and opinions related to oral and pharyngeal cancer. In February 1998 a pretested, 41-item survey was mailed to a random sample of dentists in British Columbia (n = 817) and the population of dentists in Nova Scotia (N = 423). A reminder postcard and one additional mailing were sent to nonrespondents. Of the 670 dentists supplying usable responses (response rate 55.2%), only 56.7% agreed that their knowledge of the subject was current. Of 8 health history items, dentists assessed 5 on average, with most (88.0%) asking about the patients' current use of tobacco. A total of 72.7% of the responding dentists performed an oral cancer examination for all edentulous patients at every appointment, but 10.9% never did so. Similarly, 70.7% of the dentists always provided an oral cancer examination at the initial appointment for patients 40 years of age and older, but 9.8% never did so. Undergraduate training related to oral cancer examination was reported as good by only 52.2% of the dentists. About three-quarters of all dentists (77.0%) were interested in taking continuing education courses on this subject. Differences between the 2 provinces were not statistically significant (p > 0.01). Dentists in British Columbia and Nova Scotia could benefit from undergraduate and continuing education courses to increase their knowledge of health history assessment, examination for oral and pharyngeal cancers, and risk reduction strategies, such as counselling about tobacco cessation.

  5. Application of the British Food Standards Agency nutrient profiling system in a French food composition database.

    PubMed

    Julia, Chantal; Kesse-Guyot, Emmanuelle; Touvier, Mathilde; Méjean, Caroline; Fezeu, Léopold; Hercberg, Serge

    2014-11-28

    Nutrient profiling systems are powerful tools for public health initiatives, as they aim at categorising foods according to their nutritional quality. The British Food Standards Agency (FSA) nutrient profiling system (FSA score) has been validated in a British food database, but the application of the model in other contexts has not yet been evaluated. The objective of the present study was to assess the application of the British FSA score in a French food composition database. Foods from the French NutriNet-Santé study food composition table were categorised according to their FSA score using the Office of Communication (OfCom) cut-off value ('healthier' ≤ 4 for foods and ≤ 1 for beverages; 'less healthy' >4 for foods and >1 for beverages) and distribution cut-offs (quintiles for foods, quartiles for beverages). Foods were also categorised according to the food groups used for the French Programme National Nutrition Santé (PNNS) recommendations. Foods were weighted according to their relative consumption in a sample drawn from the NutriNet-Santé study (n 4225), representative of the French population. Classification of foods according to the OfCom cut-offs was consistent with food groups described in the PNNS: 97·8 % of fruit and vegetables, 90·4 % of cereals and potatoes and only 3·8 % of sugary snacks were considered as 'healthier'. Moreover, variability in the FSA score allowed for a discrimination between subcategories in the same food group, confirming the possibility of using the FSA score as a multiple category system, for example as a basis for front-of-pack nutrition labelling. Application of the FSA score in the French context would adequately complement current public health recommendations.

  6. Association of sleep quality and free time leisure activities in Japanese and British civil servants.

    PubMed

    Nasermoaddeli, Ali; Sekine, Michikazu; Kumari, Meena; Chandola, Tarani; Marmot, Michael; Kagamimori, Sadanobu

    2005-09-01

    Sleep disturbance as a pervasive health problem can directly affect the physical and psychological well-being of individuals. Factors that positively relate to sleep quality can therefore improve healthy functioning. We examined whether leisure time activities are associated with sleep quality in two culturally different samples of civil servants. In this cross-sectional study we evaluated 1,682 Japanese, in Toyama prefecture (T) city, and 6,914 British civil servants from the Whitehall II study undertaken in London. The Japanese version of Pittsburgh sleep quality index (PSQI-J) was used in T city and Jenkins' sleep problem scale was used in the Whitehall II study. Setting a validated cut-off point of 5.5 for the PSQI-J global score and the upper tertile point for the Jenkins' sleep problem scale, we conducted logistic regression analysis to assess the association between leisure time activities and sleep quality. In both populations, those who participated in voluntary activities in clubs or organizations were significantly less likely to have poor sleep quality with Odds ratios (OR) and 95% confidence intervals (95%CI) of 0.73 (95%CI; 0.56-0.97) and 0.85 (95%CI; 0.76-0.95) in Japanese and British civil servants, respectively. Similar findings were apparent for visiting friends and relatives (ORs 0.60 (95%CI; 0.46-0.80) and 0.71 (95%CI; 0.56-0.90) for Japanese and British subjects, respectively). Our findings suggest that engagement in social leisure activities is associated with better sleep quality and consequently better general well-being.

  7. Is Smoking Behavior Culturally Determined? Evidence from British Immigrants*

    PubMed Central

    Lillard, Dean R.

    2015-01-01

    We exploit migration patterns from the UK to Australia and the US to investigate whether a person's decision to smoke is determined by culture. For each country, we use retrospective data to describe individual smoking trajectories over the life-course. For the UK, we use these trajectories to measure culture by cohort and cohort-age, and more accurately relative to the extant literature. Our proxy predicts smoking participation of second-generation British immigrants but not that of non-British immigrants and natives. Researchers can apply our strategy to estimate culture effects on other outcomes when retrospective or longitudinal data are available. PMID:25620826

  8. British National Formulary: its birth, death, and rebirth.

    PubMed Central

    Wade, O L

    1993-01-01

    The British National Formulary is a direct descendant of the National War Formulary, in which the titles of the preparations were in Latin and the doses in minims and grains. The British National Formulary was born in 1948, did a good job for about 20 years, but sickened and died in 1976. It was reborn in 1981. Parturition was painful with a very hostile reception from the media and the drug industry, but it survived and has grown in stature. The 25th edition was published in February. Wish it well for the next 25 issues! Images p1052-a p1053-a PMID:8490505

  9. 75 FR 7405 - Airworthiness Directives; British Aerospace Regional Aircraft Model Jetstream Series 3101 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Directives; British Aerospace Regional Aircraft Model Jetstream Series 3101 and Jetstream Model 3201... available in the AD docket shortly after receipt. FOR FURTHER INFORMATION CONTACT: Taylor Martin, Aerospace... AD docket. Relevant Service Information BAE Systems has issued British Aerospace Jetstream...

  10. The Rising Tide of Estuary English: The Changing Nature of Oral British Business Communication.

    ERIC Educational Resources Information Center

    Scott, James Calvert

    1995-01-01

    Defines "Estuary English," a fast-growing accent of British English that is spreading across England. Discusses its usage in the British business community; its acceptability and future; and its implications for business communicators, teachers, and consultants. (SR)

  11. Rarity, life history and scaling of the dynamics in time and space of British birds.

    PubMed

    Saether, Bernt-Erik; Grøtan, Vidar; Engen, Steinar; Noble, David G; Freckleton, Robert P

    2011-01-01

    1. Many patterns in macroecology are closely related to the total abundance of a species in a region. Here we show that interspecific differences in the pattern of population fluctuations of British bird species can be predicted from knowledge of their overall abundance and some basic life-history characteristics. 2. We identify a rarity syndrome that arises through an increased stochastic influence on population fluctuations with decreasing population size, mainly resulting from an inverse density-dependent effect of demographic stochasticity. This syndrome involves an increase in the annual changes in population size with increasing rarity in the United Kingdom. 3. The relationship between the magnitude of temporal variation and local mean population size differs between species dependent on their life history, i.e. species with larger clutch size and lower survival tended to have larger annual changes in population size than low-reproducing long-lived species. 4. The probability of local disappearance from a study plot depended on the population size and was hence closely related to the overall abundance of the species in UK. For a given population size, this probability was also related to species-specific life-history characteristics, being higher in species with larger clutch sizes and smaller survival rates. 5. Rareness results in a spatial decoupling of the temporal variation in population size. 6. These patterns show that once a species has become rare, e.g. due to human activities, key population dynamical characteristics will change because of density-dependent stochastic effects, which in turn are dependent on species-specific life-history characteristics.

  12. Management of Failing Prosthetic Bypass Grafts with Metallic Stent Placement

    SciTech Connect

    Siskin, Gary P.; Stainken, Brian F.; Mandell, Valerie S.; Darling, R. Clement; Dowling, Kyran; Herr, Allen

    1999-09-15

    Purpose: To evaluate the role of metallic stents in treating stenoses involving prosthetic arterial bypass grafts. Methods: Patients undergoing stent placement within a failing prosthetic bypass graft, during a 41-month period, were reviewed for treatment outcome and complications. The indications for stent placement in 15 patients included severe claudication (n= 3), rest pain (n= 9), and minor or major tissue loss (n= 3). Lesions were at the proximal anastomosis (n= 6), the distal anastomosis (n= 3), or within the graft (n= 6). Results: Treatment with metallic stents was successful in all patients. There was one acute stent thrombosis, successfully treated with thrombolytic therapy. Follow-up data are available for a mean duration of 12.3 months. The mean duration of primary patency was 9.4 months with 6- and 12-month primary patency rates of 51.9% and 37.0%, respectively. The mean duration of secondary patency was 12.1 months with 6- and 12-month secondary patency rates of 80.0% and 72.7%, respectively. Two patients with discontinuous runoff and preexisting gangrene required a below-knee amputation. Six patients were revised surgically after stent placement (at a mean of 10.8 months). Three late deaths occurred during follow-up. Conclusion: Given the mortality risks of surgical revision and the reduced life expectancy of this patient population, metallic stent placement represents a viable, short-term treatment option for stenoses within or at the anastomoses of prosthetic grafts. Further evaluation is warranted to compare intragraft stent placement with surgical graft revision.

  13. Earthquake recurrence models fail when earthquakes fail to reset the stress field

    USGS Publications Warehouse

    Tormann, Thessa; Wiemer, Stefan; Hardebeck, Jeanne L.

    2012-01-01

    Parkfield's regularly occurring M6 mainshocks, about every 25 years, have over two decades stoked seismologists' hopes to successfully predict an earthquake of significant size. However, with the longest known inter-event time of 38 years, the latest M6 in the series (28 Sep 2004) did not conform to any of the applied forecast models, questioning once more the predictability of earthquakes in general. Our study investigates the spatial pattern of b-values along the Parkfield segment through the seismic cycle and documents a stably stressed structure. The forecasted rate of M6 earthquakes based on Parkfield's microseismicity b-values corresponds well to observed rates. We interpret the observed b-value stability in terms of the evolution of the stress field in that area: the M6 Parkfield earthquakes do not fully unload the stress on the fault, explaining why time recurrent models fail. We present the 1989 M6.9 Loma Prieta earthquake as counter example, which did release a significant portion of the stress along its fault segment and yields a substantial change in b-values.

  14. Governing the "New Administrative Frontier:" "Cohering" Rationalities and Educational Leadership in British Columbia

    ERIC Educational Resources Information Center

    Stack, Michelle; Mazawi, Andre Elias

    2009-01-01

    In 2005, the School Leadership Society, later renamed the British Columbia Educational Leadership Council (BCELC), was launched with the assistance of the British Columbia Ministry of Education to transform the goals and objectives of educational leadership and management in the Province of British Columbia (BC), Canada. In this paper the authors…

  15. The Evolution of Capitalism: A Comparison of British and American Literature

    ERIC Educational Resources Information Center

    Stanwick, Peter A.

    2016-01-01

    This paper discusses the evolution of capitalism in British and American literature. The impact of capitalism on the lives of individuals has been well represented in both American and British literature throughout the centuries. The paper will discuss how seminal British authors such as Thomas More, William Shakespeare, Charles Dickens and George…

  16. Ethnicity and British Colonialism; The Rationale for Racially-Based Schools

    ERIC Educational Resources Information Center

    Whitehead, Clive

    2005-01-01

    This paper examines the rationale for ethnic schooling in former British colonial territories in East Africa and Southeast Asia. Critics, especially of British rule in Malaya and Singapore, have traditionally claimed that ethnic schools were established as part of a British political strategy of "divide et impera". An examination the…

  17. 76 FR 28635 - Airworthiness Directives; British Aerospace Regional Aircraft Model HP.137 Jetstream Mk.1...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... bores for cracks. Do the inspections following British Aerospace Jetstream Series 3100 & 3200 Service... the MLG leg pivot beam fastener bores for cracks. Do the inspections following British Aerospace...-004-AD; Amendment 39-16699; AD 2011-11-01] RIN 2120-AA64 Airworthiness Directives; British...

  18. Understanding the Perceptions of the British Business Community Regarding Language-Related Matters.

    ERIC Educational Resources Information Center

    Scott, James Calvert

    As the British business community becomes increasingly internationalized, it should show more interest in language-related matters. After a review of the literature, this paper reports on a study of the 100 largest British industrial companies. The conclusions are as follows: (1) a wide variety of British employees are involved in international…

  19. Attitudes toward buying online as predictors of shopping online for British and American respondents.

    PubMed

    Yang, Bijou; Lester, David; James, Simon

    2007-04-01

    This study compared the attitudes toward online shopping of British and American individuals. Using a sample of 327 British and American university students, the British respondents were found to have less favorable attitudes toward online shopping. Attitudes toward online shopping were found to be significant predictors of making online purchases. The implications of these results were discussed and suggestions made for future research.

  20. Top-rated British business research: has the emperor got any clothes?

    PubMed

    Lilford, R J; Dobbie, F; Warren, R; Braunholtz, D; Boaden, R

    2003-08-01

    Business schools have great prestige and charge large amounts of money for their courses. But how good is the science on which they base their prescriptions for action? To find out we examined the published output from the only three British business schools with the highest (5*) research assessment ranking at the time the articles were published. We conclude that theory development and model construction are often elegant. However, the methods used to obtain primary empirical information to confirm or refute the theories or populate models are poor, at least from a positivist or pragmatic ontological perspective. Large scale comparative studies made up only a small proportion of research output from the business schools. Literature reviews were not systematic. The sampling frame and rationale for selection of cases for study are inadequately described. The methods of data collection were frequently not given in sufficient detail to enable the study to be replicated and the conclusions tended to go far beyond what the data by themselves could support. However, this does not have to be the case-there are excellent examples of research in social sciences. We conclude, therefore, that top-rated British business research is a scantily clad emperor.

  1. Risk factors for heat illness among British soldiers in the hot Collective Training Environment

    PubMed Central

    Moore, Alice C; Stacey, M J; Bailey, K G H; Bunn, R J; Woods, D R; Haworth, K J; Brett, S J; Folkes, S E F

    2016-01-01

    Background Heat illness is a preventable disorder in military populations. Measures that protect vulnerable individuals and contribute to effective Immediate Treatment may reduce the impact of heat illness, but depend upon adequate understanding and awareness among Commanders and their troops. Objective To assess risk factors for heat illness in British soldiers deployed to the hot Collective Training Environment (CTE) and to explore awareness of Immediate Treatment responses. Methods An anonymous questionnaire was distributed to British soldiers deployed in the hot CTEs of Kenya and Canada. Responses were analysed to determine the prevalence of individual (Intrinsic) and Command-practice (Extrinsic) risk factors for heat illness and the self-reported awareness of key Immediate Treatment priorities (recognition, first aid and casualty evacuation). Results The prevalence of Intrinsic risk factors was relatively low in comparison with Extrinsic risk factors. The majority of respondents were aware of key Immediate Treatment responses. The most frequently reported factors in each domain were increased risk by body composition scoring, inadequate time for heat acclimatisation and insufficient briefing about casualty evacuation. Conclusions Novel data on the distribution and scale of risk factors for heat illness are presented. A collective approach to risk reduction by the accumulation of ‘marginal gains’ is proposed for the UK military. This should focus on limiting Intrinsic risk factors before deployment, reducing Extrinsic factors during training and promoting timely Immediate Treatment responses within the hot CTE. PMID:26036822

  2. Hydrocarbon concentrations and patterns in free-ranging sea otters (Enhydra lutris) from British Columbia, Canada.

    PubMed

    Harris, Kate A; Nichol, Linda M; Ross, Peter S

    2011-10-01

    With oil pollution recognized as a major threat to British Columbia's recovering sea otter (Enhydra lutris) population, it is important to distinguish acute from chronic exposures to oil constituent groups in this marine mammal. Concentrations and patterns of alkanes and polycyclic aromatic hydrocarbons (PAHs) were determined in blood samples from 29 live-captured sea otters in two coastal areas of British Columbia, as well as in representative samples of their invertebrate prey. Hydrocarbon concentrations in sea otters were similar between areas and among age and sex classes, suggesting that metabolism dominates the fate of these compounds in sea otters. Biomagnification factors derived from PAH ratios in otter:prey supported this notion. Although some higher alkylated three- and four-ring PAHs appeared to biomagnify, the majority of PAHs did not. The apparent retention of alkyl PAHs was reflected in the composition of estimated sea otter body burdens, which provided an alternative way of evaluating hydrocarbon exposure. Alkyl PAHs made up 86 ± 9% of estimated body burdens (4,340 ± 2,950 µg), with no differences between males and females (p = 0.18). The importance of measuring both parent and alkyl PAHs is underscored by their divergent dynamics in sea otters, with ready depuration of parent PAHs (metabolized or excreted) by sea otters on the one hand and biomagnification of alkyl PAHs on the other.

  3. Does Sex Matter? Temporal and Spatial Patterns of Cougar-Human Conflict in British Columbia

    PubMed Central

    Teichman, Kristine J.; Cristescu, Bogdan; Nielsen, Scott E.

    2013-01-01

    Wildlife-human conflicts occur wherever large carnivores overlap human inhabited areas. Conflict mitigation can be facilitated by understanding long-term dynamics and examining sex-structured conflict patterns. Predicting areas with high probability of conflict helps focus management strategies in order to proactively decrease carnivore mortality. We investigated the importance of cougar (Puma concolor) habitat, human landscape characteristics and the combination of habitat and human features on the temporal and spatial patterns of cougar-human conflicts in British Columbia. Conflicts (n = 1,727; 1978–2007) involved similar numbers of male and female cougars with conflict rate decreasing over the past decade. Conflicts were concentrated within the southern part of the province with the most conflicts per unit area occurring on Vancouver Island. For both sexes, the most supported spatial models for the most recent (1998–2007) conflicts contained both human and habitat variables. Conflicts were more likely to occur close to roads, at intermediate elevations and far from the northern edge of the cougar distribution range in British Columbia. Male cougar conflicts were more likely to occur in areas of intermediate human density. Unlike cougar conflicts in other regions, cattle density was not a significant predictor of conflict location. With human populations expanding, conflicts are expected to increase. Conservation tools, such as the maps predicting conflict hotspots from this study, can help focus management efforts to decrease carnivore-human conflict. PMID:24040312

  4. Autumn monitoring of resident avifauna on Guana Island, British Virgin Islands

    USGS Publications Warehouse

    Boal, Clint W.; Wunderle, Joseph M.; Arendt, Wayne J.

    2013-01-01

    Although the Caribbean region is considered a biodiversity hotspot and a priority for ecological conservation efforts, little information exists on population trends of West Indian landbirds. We combined avian survey data collected from three studies spanning a 16-year period on a small island with a minimal human presence in the British Virgin Islands. Although abundances varied among surveys, the same species were detected with rare exceptions. Despite stability in species composition, the resident landbirds were variable in their individual detectabilities. Survey detections relatively mirrored net captures for some species, but are quite different for others. We suspect that this is likely due to differences in detectability due to species-specific behaviors mediated by environmental conditions, such as rainfall, during the month or months prior to our surveys. It is difficult to assess the influence of timing or amount of precipitation on bird detections rates among our surveys due to a lack of consistent collection of location-specific weather data in the British Virgin Islands. Our study suggests monitoring efforts conducted in concert with collection of site-specific climate data would facilitate improved interpretation of survey data and a better understanding of avian species response to climate mediated changes.

  5. Does sex matter? Temporal and spatial patterns of cougar-human conflict in British Columbia.

    PubMed

    Teichman, Kristine J; Cristescu, Bogdan; Nielsen, Scott E

    2013-01-01

    Wildlife-human conflicts occur wherever large carnivores overlap human inhabited areas. Conflict mitigation can be facilitated by understanding long-term dynamics and examining sex-structured conflict patterns. Predicting areas with high probability of conflict helps focus management strategies in order to proactively decrease carnivore mortality. We investigated the importance of cougar (Puma concolor) habitat, human landscape characteristics and the combination of habitat and human features on the temporal and spatial patterns of cougar-human conflicts in British Columbia. Conflicts (n = 1,727; 1978-2007) involved similar numbers of male and female cougars with conflict rate decreasing over the past decade. Conflicts were concentrated within the southern part of the province with the most conflicts per unit area occurring on Vancouver Island. For both sexes, the most supported spatial models for the most recent (1998-2007) conflicts contained both human and habitat variables. Conflicts were more likely to occur close to roads, at intermediate elevations and far from the northern edge of the cougar distribution range in British Columbia. Male cougar conflicts were more likely to occur in areas of intermediate human density. Unlike cougar conflicts in other regions, cattle density was not a significant predictor of conflict location. With human populations expanding, conflicts are expected to increase. Conservation tools, such as the maps predicting conflict hotspots from this study, can help focus management efforts to decrease carnivore-human conflict.

  6. Reliability of the Kinetics of British Army Foot Drill in Untrained Personnel.

    PubMed

    Rawcliffe, Alex J; Simpson, Richard J; Graham, Scott M; Psycharakis, Stelios G; Moir, Gavin L; Connaboy, Chris

    2017-02-01

    Rawcliffe, AJ, Simpson, RJ, Graham, SM, Psycharakis, SG, Moir, GL, and Connaboy, C. Reliability of the kinetics of British Army foot drill in untrained personnel. J Strength Cond Res 31(2): 435-444, 2017-The purpose of this study was to quantify the reliability of kinetic variables of British Army foot drill performance within untrained civilians and report the magnitude of vertical ground reaction force (vGRF) and vertical rate of force development (RFD) of foot drills. Fifteen recreational active males performed 3 testing sessions across a 1-week period, with each session separated by 24 hours. Within each testing session participants (mean ± SD; age 22.4 ± 1.7 years; height 177 ± 5.6 cm; weight 83 ± 8.7 kg) completed 10 trials of stand-at-attention (SaA), stand-at-ease (SaE), Halt, quick-march (QM) and a normal walking gait, with vGRF and vertical RFD measured on a force plate. Between-session and within-session reliability was calculated as systematic bias, coefficient of variation calculated from the typical error (CVte%), and intraclass correlation coefficient (ICC). Significant (p ≤ 0.05) between-session differences were found for the vGRF SaA and SaE, and vertical RFD SaA and SaE conditions. Significant (p ≤ 0.05) within-session differences were found for the vGRF SaA and SaE conditions. A mean vGRF CVte% ≤10% was observed across all foot drills. However, the mean vertical RFD CVte% observed was ≥10% (excluding SaE) across all foot drills. The ICC analyses indicated that the vGRF Halt, QM, SaA, and Walk condition achieved moderate to large levels of test-retest reliability, with only SaE failing to achieve an ICC value ≥0.75. The vertical RFD QM, SaE, and Walk condition achieved moderate levels of test-retest reliability, with Halt and SaA failing to achieve an ICC value ≥0.75. It was determined that a single familiarization session and using the mean of 8 trials of vGRF are required to achieve acceptable levels of reliability.

  7. Discriminant Analysis of a Spatially Extensive Landsliding Inventory for the Haida Gwaii, British Columbia, Canada

    NASA Astrophysics Data System (ADS)

    Sjogren, D.; Martin, Y. E.; Jagielko, L.

    2010-12-01

    Gimbarzevsky (1988) collected an exceptional landsliding inventory for the Haida Gwaii, British Columbia (formerly called the Queen Charlotte Islands). This data base includes more than 8 000 landsliding vectors, with an areal coverage of about 10 000 km2. Unfortunately, this landsliding inventory was never published in the referred literature, despite its regional significance. The data collection occurred prior to widespread use of GIS technologies in landsliding analysis, thus restricting the types of analyses that were undertaken at the time relative to what is possible today. Gimbarzevsky identified the landsliding events from 1:50 000 aerial photographs, and then transferred the landslide vectors to NTS map sheets. In this study, we digitized the landslide vectors from these original map sheets and connected each vector to a digital elevation model. Lengths of landslide vectors were then compared to results of Rood (1984), whose landsliding inventory for the Haida Gwaii relied on larger-scale aerial photographs (~ 1:13 000). A comparison of the two data bases shows that Rood’s inventory contains a more complete record of smaller landslides, whereas Gimbarzevsky’s inventory provides a much better statistical representation of less frequently occurring, medium to large landslide events. We then apply discriminant analysis to the Gimbarzevsky data base to assess which of a set of ten predictor variables, selected on the basis of mechanical theory, best predict failed vs. unfailed locations in the landscape (referred to as the grouping variable in discriminant analysis). Certain predictor variables may be cross-correlated, and any one particular variable may be related to several aspects of mechanical theory (for example, a particular variable may affect various components of shear stress and/or shear strength); it is important to recognize that the significance of particular groupings may reflect this information. Eight of the original variables were found

  8. Youth, Heroin, Crack: A Review of Recent British Trends

    ERIC Educational Resources Information Center

    Seddon, Toby

    2008-01-01

    Purpose: The purpose of this paper is to review the research evidence on recent British trends in the use of heroin and/or crack-cocaine by young people in order to appraise the scale and nature of the contemporary health problem they pose. Design/methodology/approach: The approach consists of a narrative review of the main current data sources on…

  9. Popular Music Pedagogy: Band Rehearsals at British Universities

    ERIC Educational Resources Information Center

    Pulman, Mark

    2014-01-01

    There has been little published pedagogical research on popular music group rehearsing. This study explores the perceptions of tutors and student pop/rock bands about the rehearsals in which they were involved as a part of their university music course. The participants were 10 tutors and 16 bands from eight British tertiary institutions. Analysis…

  10. Modernised Learning: An Emerging Lifelong Agenda by British Trade Unions?

    ERIC Educational Resources Information Center

    Forrester, Keith P.

    2001-01-01

    British trade unions' engagement in workplace learning is currently shaped by discourses of globalization and the learning society. Unions' workplace learning representatives appear more focused on uncritical acceptance of learning for employability and less on learning for active citizenship and workplace democracy. (Contains 21 references.) (SK)

  11. Rethinking Apprenticeship Training in the British Construction Industry

    ERIC Educational Resources Information Center

    Abdel-Wahab, Mohamed

    2012-01-01

    The British government continued intervention to support apprenticeship training across the economy has been notable in recent years. The construction industry is the only sector to retain a levy/grant scheme (that supports training including apprenticeships) since 1964, yet it still faces the problem of skills shortages. This article thus reviews…

  12. British Literature: Discipline Analysis. Women in the Curriculum Series.

    ERIC Educational Resources Information Center

    Wolfson, Susan

    This essay examines the ways in which British literature, as a discipline, has been influenced by feminist scholarship and research into the areas of gender and sexuality. It reports that feminist literary criticism took definitive shape in the late 1960s as part of the women's liberation movement, and that a central concern of this first…

  13. Comment: The People's Law School of British Columbia.

    ERIC Educational Resources Information Center

    Sprowls, David

    1980-01-01

    The People's Law School of British Columbia is a nonprofit organization informing laymen of their legal rights and responsibilities. The program features free evening courses cosponsored by community groups in 60 centers around the province. (Journal availability: Canada-United States Law Journal, 11075 East Blvd., Cleveland, OH 44106.) (MSE)

  14. Student Perceptions of Student Interaction in a British EFL Setting

    ERIC Educational Resources Information Center

    Kuo, I-Chun

    2011-01-01

    This article reports on an investigation into how learners in a British EFL setting perceive the classroom practice of student-student interaction and why it is perceived in these ways. Adopting qualitative non-experimental methods, I first explored issues leading to the concept of "usefulness" and identified factors that appeared to…

  15. The British Middle School at Age Thirty: An American Perspective.

    ERIC Educational Resources Information Center

    Hertzog, C. Jay

    A historical overview of the development of the British middle school system is presented in this paper, with a focus on the impact of the national curriculum established by the Education Reform Act of 1988. Based on field observation, information is presented on curriculum, the role of head teachers and faculty, parental involvement, and student…

  16. Language Choice and Communicative Intent in a British Black Community.

    ERIC Educational Resources Information Center

    Edwards, Viv

    Current patterns of Patois (introduced by West Indian Creoles) as used by young Jamaicans in England is presented. Forty-five British-born individuals, aged 16 to 23, whose parents were Jamaican immigrants, participated in a study structured to elicit a wide range of speech patterns. Subjects differed greatly in educational background and in…

  17. Motherhood, Choice and the British Media: A Time to Reflect

    ERIC Educational Resources Information Center

    Hadfield, L.; Rudoe, N.; Sanderson-Mann, J.

    2007-01-01

    In this paper we ask: How is motherhood being represented in the British media, especially in relation to choice, age and fertility? Do media discourses reflect a redefinition or transformation of "motherhood" in the twenty-first century, and what implications do they have for feminist research into maternal identity and motherhood? As…

  18. A Brief History of the Transfer System in British Columbia

    ERIC Educational Resources Information Center

    Gaber, Devron

    2005-01-01

    This document presents a brief history of important events in the development and maintenance of the post-secondary transfer system in British Columbia (BC) over the last six decades. Information is presented in point form and in chronological order. Several points related to the expansion of the post-secondary system are included, and hence the…

  19. Educational Developments in the British West Indies: A Historical Overview

    ERIC Educational Resources Information Center

    Coates, Chad O.

    2012-01-01

    Formal education within the English-speaking Caribbean Community (CARICOM) may be traced back to the establishment of Codrington grammar school in Barbados in 1743. After more than two centuries of British colonial rule the educational systems within CARICOM states continue to reflect the academic traditions of their former colonizer. Prior to…

  20. A Review of Special Education in British Columbia.

    ERIC Educational Resources Information Center

    Siegel, Linda; Ladyman, Stewart

    This report presents findings of a special team to review special education policy, its implementation, accountability, and program effectiveness in British Columbia. The team identified a set of issues to address including: inclusion/integration, parental involvement, assessment, Individual Education Plans, evaluation, transitions, employees who…

  1. The 1990 British Columbia Mathematics Assessment: Technical Report.

    ERIC Educational Resources Information Center

    Robitaille, David F., Ed.

    This book presents the results of the fourth British Columbia Mathematics Assessment conducted in the spring of 1990. Students in Grades 4, 7, and 10 (approximately 120,000) were asked to provide information about themselves, to express their opinions about school-related experiences, and to demonstrate their ability to do the mathematics…

  2. The Pricing of British Journals for the North American Market.

    ERIC Educational Resources Information Center

    Tuttle, Marcia

    1986-01-01

    Presents an informal report of seminar entitled "Learned Journals: The Problem of Pricing and Buying Round," held in London on March 22, 1985, in attempt to answer charges of discriminatory pricing. Price differential of British scholarly journals, costs, marketing, and role of subscription agent are discussed. Seven sources are given.…

  3. How Activity Systems Evolve: Making / Saving Salmon in British Columbia

    ERIC Educational Resources Information Center

    Lee, Yew-Jin; Roth, Wolff-Michael

    2008-01-01

    The purpose of this article is to describe the history of a state-sponsored salmon enhancement project in British Columbia and to explicate the development of the former using cultural historical activity theory. We make thematic the notion of inner contradictions, which express themselves outwardly as a function of both quantitative and…

  4. Strategic Management of Quality: An American and British Perspective.

    ERIC Educational Resources Information Center

    Weller, L. David; McElwee, Gerard

    1997-01-01

    Total Quality Management is being implemented in American and British schools to improve educational outcomes. The 14 points of Deming's quality model and Porter's models of competition and drivers of cost provide a systematic, structured template to promote educational excellence and meet the demands of social, political, and economic forces.…

  5. At the margin: continuing crisis in British environmental history?

    PubMed

    Luckin, Bill

    2004-09-01

    An understanding of historical relations between gender and nature, whether within the context of 'untouched wilderness' or the pulsating vibrancy of the industrial city, is central to collective self-knowledge in the world in which we all live. However, have British historians been less successful than their American counterparts in engaging with key aspects of the environmental past?

  6. The Discursive Framing of International Education Programs in British Columbia

    ERIC Educational Resources Information Center

    Cover, Dwayne

    2016-01-01

    This study examines how international education programs in British Columbia have been discursively framed by government and media sources. Over the past two decades, international education programs have expanded in number and scale in the province, a phenomenon that has been interpreted by some education researchers and media sources as…

  7. The British Columbia Literature 12 Curriculum and I: A Soliloquy

    ERIC Educational Resources Information Center

    Kouritzin, Sandra G.

    2004-01-01

    A critique of the prescribed Literature 12 curriculum for British Columbia teachers, this article is a life-history narrative juxtaposed against my own literary education, examining how my lived experiences were reflected and reinforced in the Literature 12 curriculum, and in the literary canons of both high school and university English teaching…

  8. Modern British Literature: Sources for Criticism. A Research Guide.

    ERIC Educational Resources Information Center

    Van Noate, Judith, Comp.

    This handout is a guide to library resources in the J. Murrey Atkins Library at the University of North Carolina-Charlotte, intended to help students find sources of criticism on Modern British Literature (long fiction, short fiction, poetry, and drama). The guide explains important reference sources in the Atkins library reference collection and…

  9. A Pragmatic Study of Exaggeration in British and American Novels

    ERIC Educational Resources Information Center

    Abbas, Qassim; Al-Tufaili, Dhayef

    2016-01-01

    The main concern of this study is to tackle exaggeration in British and American situations taken from "Mrs. Dalloway" and "The Great Gatsby" novels. From a pragmatic point of view, exaggeration in the field of literature has not been given enough attention. Accordingly, this study is an attempt to develop a model for the…

  10. The Linguistics of British Sign Language: An Introduction.

    ERIC Educational Resources Information Center

    Sutton-Spence, Rachel; Woll, Bencie

    This textbook provides support for learners of British Sign Language (BSL) and others interested in the structure and use of BSL, and assumes no previous knowledge of linguistics or sign language; technical terms and linguistic jargon are kept to a minimum. The text contains many examples from English, BSL, and other spoken and signed languages,…

  11. Emigration, Internationalization, and "Brain Drain": Propensities among British Academics.

    ERIC Educational Resources Information Center

    Schuster, Jack H.

    1994-01-01

    A survey of 2,017 British university faculty found that over 40% were seriously considering moving abroad, with a substantial majority favoring the United States. Other variables examined include academic field, research versus teaching orientation, academic rank, age, gender, political identification, former polytechnic versus university…

  12. Deaf People as British Sign Language Teachers: Experiences and Aspirations

    ERIC Educational Resources Information Center

    Atherton, Martin; Barnes, Lynne

    2012-01-01

    Little research has been undertaken into the profession of British Sign Language (BSL) teaching, despite a huge increase in the number of BSL classes offered over the past twenty years. Following the introduction of Qualified Teacher Learning and Skills standards in 2007, BSL teachers working in "further education" (FE) colleges were…

  13. Judging Risk: Key Determinants in British Domestic Violence Cases

    ERIC Educational Resources Information Center

    Robinson, Amanda L.; Howarth, Emma

    2012-01-01

    Data from the largest study to date of the working practices of British victim support workers (known as Independent Domestic Violence Advisors or IDVAs) are used to provide insight into how "risk judgments" are made in cases of domestic violence. Using data from more than 2,000 victims, this study found a convergence between actuarial…

  14. A British Intellectual Pioneers a New Model for College

    ERIC Educational Resources Information Center

    Labi, Aisha

    2013-01-01

    This article profiles A.C. Grayling, a British intellectual who pioneers a new model for college. In his role as founder of the New College of the Humanities, Britain's newest and most controversial institution of higher education, A.C. Grayling could have chosen among several titles. The senior academic officer at most English higher-education…

  15. Did Francis Drake bring Chilean potatoes to the British Isles

    Technology Transfer Automated Retrieval System (TEKTRAN)

    R.N Salaman, in 1937, speculated that the first potatoes cultivated in Great Britain and northern Europe were obtained by Francis Drake at Cartagena, Colombia and brought to the British Isles in the 1570-80’s. Presumably S. andigenum tubers would have been brought down the 500 miles from Bogotá to C...

  16. Discipline and the Discipline: Histories of the British Public Library.

    ERIC Educational Resources Information Center

    Peatling, G. K.

    2003-01-01

    Suggests that historians of British public libraries may be restricted in their ability to pose certain questions about their subject matter because of the structure of the institutions of library history. Discusses problem patrons; critiques of public libraries; and library access and social exclusion. (Contains 95 references.) (Author/LRW)

  17. John Dewey's Democracy and Education: A British Tribute

    ERIC Educational Resources Information Center

    Higgins, Steve, Ed.; Coffield, Frank, Ed.

    2016-01-01

    In 1916 John Dewey published "Democracy and Education: An introduction to the philosophy of education". In this book some of today's foremost historians, philosophers, psychologists, and sociologists of education mark the anniversary of Dewey's work by reviewing and reflecting, from a British perspective, on Dewey's contribution to our…

  18. Export Market Orientation Behavior of Universities: The British Scenario

    ERIC Educational Resources Information Center

    Asaad, Yousra; Melewar, T. C.; Cohen, Geraldine

    2015-01-01

    This study seeks to extend our knowledge of export market orientation (EMO) in the context of British universities with regard to recruitment of international students. Export marketing remains an area of limited focus in the marketization of higher education literature. The study predominantly follows a quantitative research design using survey…

  19. Labour Trends and Training Needs in British Columbia.

    ERIC Educational Resources Information Center

    Walker, Susan P.

    In an effort to meet the training needs of the British Columbia (BC) labor force, Open College (OC), in Burnaby, has focused future activities on market-driven, employer-centered training programs utilizing advanced technologies and traditional on-site instructional methods. Designed to ensure that these courses and programs reflect actual labor…

  20. The British Peace Movement in the 1980's.

    ERIC Educational Resources Information Center

    Reader, Mark

    The groups and personalities that comprise the British peace network are discussed and their activities are examined. The nuclear disarmament campaign is led by a combination of mass-based organizations, specialized interest groups, and individuals determined to end Britain's role as a nuclear weapons state and military base. Notable groups are…

  1. Olive Banks and the Collective Biography of British Feminism

    ERIC Educational Resources Information Center

    Weiner, Gaby

    2008-01-01

    This paper considers Olive Banks' work on charting the history and development of British feminism, and particularly her use of collective biography as a research and analytic tool. It is argued that while this has been seen as the least "fashionable" aspect of her work, it took forward C. Wright Mills' contention for one definition of…

  2. Learning to Be. A Perspective from British Columbia, Canada

    ERIC Educational Resources Information Center

    Halbert, Judy; Kaser, Linda

    2015-01-01

    This article describes how "learning to be", with a specific focus on social-emotional competencies, has become part of the educational mindset--and educational policy--in British Columbia, Canada. The development of a set of learning progressions for social responsibility, an emphasis on social emotional learning in the new curriculum…

  3. Soldier Education in the British Army, 1920-2007

    ERIC Educational Resources Information Center

    Beach, Jim

    2008-01-01

    This article surveys the history of compulsory education for soldiers' career advancement in the British army. It begins with an examination of the organizational context before analyzing the rationale, syllabus, teaching and assessment of soldier education. It concludes that for members of the army education organization their self-perception as…

  4. Cutaneous leishmaniasis in British troops following jungle training in Belize.

    PubMed

    Bailey, Mark S

    2011-09-01

    British military personnel account for 45% of cutaneous leishmaniasis (CL) cases seen in the UK and 103 cases from Belize were seen in 1998-2009. Systemic treatment of CL from Belize should not be considered essential in immunocompetent patients because mucosal leishmaniasis very rarely occurs.

  5. Mission Groups and the New Politics of British Higher Education

    ERIC Educational Resources Information Center

    Filippakou, Ourania; Tapper, Ted

    2015-01-01

    This article explores the emergence and impact of the mission groups in British higher education. The central argument is that given the development of a mass and diversified model of higher education it was inevitable that the higher education institutions would form pressure groups, while increased marketisation and growing inter-institutional…

  6. Teaching Culture during the Sixties: A British Perspective.

    ERIC Educational Resources Information Center

    Peters, Laurence

    In the 1960s many teachers in the British secondary schools began a major effort to redefine their attitude toward the mass media in the light of certain social and cultural pressures. Changes in students made it necessary to provide materials of a less formal academic kind and to introduce literature, music, and art that would relate more…

  7. Educating for Europe: The Knowledge and Understanding of British Children

    ERIC Educational Resources Information Center

    Holden, Cathie

    2004-01-01

    Teacher educators from eight European countries undertook a collaborative study into children's understanding of their own national and European identity, their understanding of the geography and cultures of Europe and finally their understanding of how countries are governed. The views of the British children are reported here, set alongside a…

  8. Educator Preparedness to Teach Health Education in British Columbia

    ERIC Educational Resources Information Center

    Vamos, Sandra; Zhou, Mingming

    2007-01-01

    Background: To date, few studies have been conducted to investigate the preparedness of health educators in Canadian school systems. Purpose: This study assessed practicing and pre-service teachers' self-perceptions of preparedness to teach health education in British Columbia K-12 classrooms. It also investigated factors related to their…

  9. Eight Teaching Modules for a Course on Major British Authors.

    ERIC Educational Resources Information Center

    Smith, Denzell

    Each of eight modules in this course guide focuses on a specific work of British literature from a particular historical period. Each module contains descriptions of rationale, objectives, instructional activities, postassessment, remediation procedures for that particular unit of study, and a list of titles for additional reading. Subjects of the…

  10. The British Library Initiatives for Access Seminar: Digital Imaging.

    ERIC Educational Resources Information Center

    Alexander, Michael

    1996-01-01

    Provides an overview of the British Library's Initiatives for Access program which uses digital imaging. Highlights include digitization of microfilm, the electronic "Beowulf", electronic photographic viewing system, computer software that uses neural networks and fuzzy matching to provide links to search terms, and international…

  11. Ethnic, Gender and Class Intersections in British Women's Leadership Experiences

    ERIC Educational Resources Information Center

    Showunmi, Victoria; Atewologun, Doyin; Bebbington, Diane

    2016-01-01

    A qualitative study was conducted to examine how gender and ethnicity influenced leadership experiences of a mixed ethnic sample of British women. An intersectional framework was used which took the viewpoint that socio-demographic identities should be considered simultaneously in order to challenge universalist, gender and ethnic neutral…

  12. A comparison of physical activity and sedentary behaviour in 9–11 year old British Pakistani and White British girls: a mixed methods study

    PubMed Central

    2014-01-01

    Background Previous studies suggest that British children of South Asian origin are less active and more sedentary than White British children. However, little is known about the behaviours underlying low activity levels, nor the familial contexts of active and sedentary behaviours in these groups. Our aim was to test hypotheses about differences between British Pakistani and White British girls using accelerometry and self-reports of key active and sedentary behaviours, and to obtain an understanding of factors affecting these behaviours using parental interviews. Methods Participants were 145 girls (70 White British and 75 British Pakistani) aged 9–11 years and parents of 19 of the girls. Accelerometry data were collected over 4 days and girls provided 24-hour physical activity interviews on 3 of these days. Multilevel linear regression models and generalised linear mixed models tested for ethnic differences in activity, sedentary time, and behaviours. Semi-structured interviews were conducted with parents. Results Compared to White British girls, British Pakistani girls accumulated 102 (95% CI 59, 145) fewer counts per minute and 14 minutes (95% CI 8, 20) less time in moderate to vigorous physical activity per day. British Pakistani girls spent more time (28 minutes per day, 95% CI 14, 42) sedentary. Fewer British Pakistani than White British girls reported participation in organised sports and exercise (OR 0.22 95% CI 0.08, 0.64) or in outdoor play (OR 0.42 95% CI 0.20, 0.91). Fewer British Pakistani girls travelled actively to school (OR 0.26 95% CI 0.10, 0.71). There was no significant difference in reported screen time (OR 0.88 95% CI 0.45, 1.73). Parental interviews suggested that structural constraints (e.g. busy family schedules) and parental concerns about safety were important influences on activity levels. Conclusions British Pakistani girls were less active than White British girls and were less likely to participate in key active behaviours

  13. Differences in obstetric care among nulliparous First Nations and non–First Nations women in British Columbia, Canada

    PubMed Central

    Riddell, Corinne A.; Hutcheon, Jennifer A.; Dahlgren, Leanne S.

    2016-01-01

    Background: Canada’s Aboriginal population faces significantly higher rates of stillbirth and neonatal and postnatal death than those seen in the general population. The objective of this study was to compare indicators of obstetric care quality and use of obstetric interventions between First Nations and non-First Nations mothers in British Columbia, Canada. Methods: We linked obstetrical medical records with the First Nations Client File for all nulliparous women who delivered single infants in British Columbia from 1999 to 2011. Using logistic regression models, we examined differences in the proportion of women who received services aligned with best practice guidelines, as well as the overall use of obstetric interventions among First Nations mothers compared with the general population, controlling for geographic barriers (distance to hospital) and other relevant confounders. Results: During the study period, 215 993 single births occurred in nulliparous women in British Columbia, 9152 of which were to members of our First Nations cohort. First Nations mothers were less likely to have early ultrasonography (adjusted risk difference = 10.2 fewer women per 100 deliveries [95% confidence interval {CI} −11.3 to −9.3]), to have at least 4 antenatal care visits (3.6 fewer women per 100 deliveries [95% CI −4.6 to −2.6]), and to undergo labour induction after prolonged (> 24 hours) prelabour rupture of membranes (−5.9 [95% CI −11.8 to 0.1]) or at post-dates gestation (−10.6 [95% CI −13.8 to −7.5]). Obstetric interventions including epidural, labour induction, instrumental delivery and cesarean delivery were used less often in First Nations mothers. Interpretation: We identified differences in the obstetric care received by First Nations mothers compared with the general population. Such differences warrant further investigation, given increases in perinatal mortality that are consistently shown and that may be a downstream consequence of

  14. In Situ Optimal Reshading of Arrays with Failed Elements

    DTIC Science & Technology

    2016-06-13

    unlimited 13. SUPPLEMENTARY NOTES NUWC2015 14. ABSTRACT An algorithm is presented which computes optimal weights for arbitrary linear arrays. The...application of this algorithm to in situ optimal reshading of arrays with failed elements is discussed. It is shown that optimal reshading can often...which computes optimal weights for arbitrary linear arrays. The application of this algorithm to in situ optimal reshading of arrays with failed

  15. Laser explantation of a failing endosseous dental implant.

    PubMed

    Smith, L P; Rose, T

    2010-06-01

    Explantation of failed dental implants has traditionally been performed by mechanical bone removal techniques. The advent of intraoral laser surgery has seen increasing numbers of applications in oral implantology. The technique demonstrates safe and efficient explantation of a failed dental implant using Er,Cr:YSGG laser. Laser assisted explantation of dental implants is a minimally invasive technique providing an alternative to conventional mechanical explantation techniques.

  16. Sir William Howe: A Study in Failed Strategic Leadership

    DTIC Science & Technology

    2013-03-01

    withdrawal, Washington increased the credibility of the American cause both at home and in the international community “for with the forcing of the...as to why a sea-borne move was ill advised. Howe’s answer to this being “I have sent my plan home and it has been approved.”52 The result of the...pillaging and rape . In New Jersey some of the worst misconduct of the war occurred as the British “indiscriminately terrorized the rebels, the

  17. Public health in interwar England and Wales: did it fail?

    PubMed

    Gorsky, Martin

    2008-01-01

    British historians initially saw the interwar period as a "golden age" for public health in local government, with unprecedented preventive and curative powers wielded by Medical Officers of Health (MOsH). In the 1980s Lewis and Webster challenged this reading, arguing that MOsH were overstretched, neglectful of their "watchdog" role and incapable of formulating a new philosophy of preventive medicine. The article first details this critique, then reappraises it in the light of recent demographic work. It then provides a case study of public health administration in South-West England. Its conclusion is that some elements of the Lewis/Webster case now deserve to be revised.

  18. Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft

    PubMed Central

    Desai, Nirmit; Patel, Sagar; Nwosu, Chinyere; Sung, Lok; Buscaglia, Jonathan M.; Nord, Edward P.; Wadhwa, Nand K.

    2013-01-01

    We present a case of a patient with a failed pancreaticoduodenal allograft with exocrine enteric-drainage who developed catastrophic gastrointestinal (GI) hemorrhage. Over the course of a week, she presented with recurrent GI bleeds of obscure etiology. Multiple esophago-gastro-duodenoscopic (EGD) and colonoscopic evaluations failed to reveal the source of the hemorrhage. A capsule endoscopy and a technetium-labeled red blood cells (RBC) imaging study were similarly unrevealing for source of bleeding. She subsequently developed hemorrhagic shock requiring emergent superior mesenteric arteriography. Run off images revealed an external iliac artery aneurysm with fistulization into the jejunum. Coiled embolization was attempted but abandoned because of hemodynamic instability. Deployment of a covered endovascular stent into the right external iliac artery over the fistula site resulted in immediate hemodynamic stabilization. A high index of suspicion for arterioenteric fistulae is needed for diagnosis of this uncommon but eminently treatable form of GI hemorrhage in this patient population. PMID:24455393

  19. Reduction in cervical intraepithelial neoplasia in young women in British Columbia after introduction of the HPV vaccine: An ecological analysis.

    PubMed

    Ogilvie, Gina S; Naus, Monika; Money, Deborah M; Dobson, Simon R; Miller, Dianne; Krajden, Mel; van Niekerk, Dirk J; Coldman, Andrew J

    2015-10-15

    We report on the rates of cervical intraepithelial neoplasia (CIN) in young women aged 15-22 years of age in British Columbia before and after the introduction of an HPV vaccine program. Rates of cervical intraepithelial neoplasia (CIN) 2+ for each age stratum (15-22) in the calendar years 2004-2012 for the province of British Columbia were obtained from the BC Cancer Agency's population-based cervical cancer program. Incidence rate ratios (IRR) of CIN2+ were described and compared before and after HPV vaccine program introduction in cohorts born in vaccine eligible years, and in non-vaccine eligible years using piece-wise Poisson regression analysis, and adjusted for age. Between 2004 and 2012, rates of CIN2 and CIN2+ in young women aged 15-22 years in the province of British Columbia have decreased overall. After the introduction of the HPV vaccine program, the age adjusted IRR for CIN2+ for young women aged 15-17 years decreased significantly from 0.91 (95% CI: 0.86-0.98 p < 0.01) to 0.36 (95% CI: 0.18-0.73 p < 0.01). During the same time period, no similar reduction was found in young women 18-22 years. After introduction of HPV vaccine program, IRR for CIN2+ in young women 15-17 was significantly reduced for CIN2+ (0.14; 95% CI: 0.04- 0.47; p < 0.01) and CIN2 (0.1; 95% CI: 0.02-0.54; p < 0.01). This ecological analysis shows a significant reduction in CIN2+ lesions in young women aged 15-17 years in British Columbia after the introduction of the HPV vaccine in young women despite vaccine uptake levels below 70%.

  20. Authoritarian parenting attitudes as a risk for conduct problems Results from a British national cohort study.

    PubMed

    Thompson, Anne; Hollis, Chris; Dagger, David Richards

    2003-04-01

    This study examines the associations, and possible causal relationship, between mothers' authoritarian attitudes to discipline and child behaviour using cross-sectional and prospective data from a large population sample surveyed in the 1970 British Cohort Study. Results show a clear linear relationship between the degree of maternal approval of authoritarian child-rearing attitudes and the rates of conduct problems at age 5 and age 10. This association is independent of the confounding effects of socio-economic status and maternal psychological distress. Maternal authoritarian attitudes independently predicted the development of conduct problems 5 years later at age 10. The results of this longitudinal study suggest that authoritarian parenting attitudes expressed by mothers may be of significance in the development of conduct problems.

  1. The ichneumon fly and the equilibration of British natural economies in the eighteenth century.

    PubMed

    Wille, Sheila

    2015-12-01

    The parasitic ichneumon fly, discovered by European natural philosophers in the seventeenth century, remained largely unstudied until it captured the attention of Enlightenment-era natural historians. Although this sudden surge of interest has been explained as an effort to understand the natural 'evil' of parasitism, the heyday of ichneumon studies was actually inspired by the political and agricultural context of late eighteenth-century Britain. British naturalists were captivated by this insect for reasons both philosophical and practical. In the providentially self-equilibrating qualities of 'natural' ichneumon economies, they saw solutions to political problems of famine, dearth, national wealth, governance and excess population, in addition to finding reassurance that Enlightened confidence in nature's inherent stability and fruitfulness was not unfounded.

  2. A Novel and Likely Inherited Lymphoproliferative Disease in British Shorthair Kittens.

    PubMed

    Aberdein, D; Munday, J S; Fairley, R A; Vernau, W; Thompson, K G

    2015-11-01

    An unusual lymphoproliferative disease was identified in multiple closely related British Shorthair (BSH) kittens, suggesting an inherited predisposition to disease. Affected kittens typically developed rapidly progressive and marked generalized lymphadenopathy, moderate splenomegaly, and regenerative and likely hemolytic anemia from 6 weeks of age. Microscopic findings were suggestive of multicentric T-cell lymphoma, but additional testing revealed a polyclonal population of CD3+/CD4-/CD8- "double negative" T cells (DNT cells). This is a novel disease presentation with similarities to the human disorder autoimmune lymphoproliferative syndrome (ALPS), a rare inherited disease causing lymphoproliferation and variable manifestations of autoimmunity. The human disease is most commonly due to the presence of Fas gene mutations causing defective lymphocyte apoptosis, and further investigations of both the mode of inheritance and genetic basis for disease in affected cats are currently in progress.

  3. Outbreak of cyclosporiasis in British Columbia associated with imported Thai basil.

    PubMed Central

    Hoang, L. M. N.; Fyfe, M.; Ong, C.; Harb, J.; Champagne, S.; Dixon, B.; Isaac-Renton, J.

    2005-01-01

    Sporadic outbreaks of cyclosporiasis, a common cause of protracted diarrhoea in underdeveloped countries, are often undetected and undiagnosed in industrial countries. In May 2001, an outbreak of Cyclospora cayetanensis gastroenteritis was identified in British Columbia, Canada, with 17 reported cases. We conducted a case-control study involving 12 out of the 17 reported and confirmed case patients. Eleven (92%) of the patients had consumed Thai basil, an essential ingredient in Vietnamese cuisine, compared to 3 out of 16 (19%) of the control patients (P = 0.003). Trace-back investigations implicated Thai basil imported via the United States as the vehicle for this outbreak. This is the first documented sporadic outbreak of cyclosporiasis linked to Thai basil in Canada, and the first outbreak of cyclosporiasis identified in an ethnic immigrant population. This outbreak provides the opportunity to increase our understanding of this emerging pathogen and improve on our prevention and control for future outbreaks. PMID:15724706

  4. Outbreak of cyclosporiasis in British Columbia associated with imported Thai basil.

    PubMed

    Hoang, L M N; Fyfe, M; Ong, C; Harb, J; Champagne, S; Dixon, B; Isaac-Renton, J

    2005-02-01

    Sporadic outbreaks of cyclosporiasis, a common cause of protracted diarrhoea in underdeveloped countries, are often undetected and undiagnosed in industrial countries. In May 2001, an outbreak of Cyclospora cayetanensis gastroenteritis was identified in British Columbia, Canada, with 17 reported cases. We conducted a case-control study involving 12 out of the 17 reported and confirmed case patients. Eleven (92%) of the patients had consumed Thai basil, an essential ingredient in Vietnamese cuisine, compared to 3 out of 16 (19%) of the control patients (P = 0.003). Trace-back investigations implicated Thai basil imported via the United States as the vehicle for this outbreak. This is the first documented sporadic outbreak of cyclosporiasis linked to Thai basil in Canada, and the first outbreak of cyclosporiasis identified in an ethnic immigrant population. This outbreak provides the opportunity to increase our understanding of this emerging pathogen and improve on our prevention and control for future outbreaks.

  5. Cryptococcus gattii dispersal mechanisms, British Columbia, Canada.

    PubMed

    Kidd, Sarah E; Bach, Paxton J; Hingston, Adrian O; Mak, Sunny; Chow, Yat; MacDougall, Laura; Kronstad, James W; Bartlett, Karen H

    2007-01-01

    Recent Cryptococcus gattii infections in humans and animals without travel history to Vancouver Island, as well as environmental isolations of the organism in other areas of the Pacific Northwest, led to an investigation of potential dispersal mechanisms. Longitudinal analysis of C. gattii presence in trees and soil showed patterns of permanent, intermittent, and transient colonization, reflecting C. gattii population dynamics once the pathogen is introduced to a new site. Systematic sampling showed C. gattii was associated with high-traffic locations. In addition, C. gattii was isolated from the wheel wells of vehicles on Vancouver Island and the mainland and on footwear, consistent with anthropogenic dispersal of the organism. Increased levels of airborne C. gattii were detected during forestry and municipal activities such as wood chipping, the byproducts of which are frequently used in park landscaping. C. gattii dispersal by these mechanisms may be a useful model for other emerging pathogens.

  6. Cryptococcus gattii Dispersal Mechanisms, British Columbia, Canada

    PubMed Central

    Kidd, Sarah E.; Bach, Paxton J.; Hingston, Adrian O.; Mak, Sunny; Chow, Yat; MacDougall, Laura; Kronstad, James W.

    2007-01-01

    Recent Cryptococcus gattii infections in humans and animals without travel history to Vancouver Island, as well as environmental isolations of the organism in other areas of the Pacific Northwest, led to an investigation of potential dispersal mechanisms. Longitudinal analysis of C. gattii presence in trees and soil showed patterns of permanent, intermittent, and transient colonization, reflecting C. gattii population dynamics once the pathogen is introduced to a new site. Systematic sampling showed C. gattii was associated with high-traffic locations. In addition, C. gattii was isolated from the wheel wells of vehicles on Vancouver Island and the mainland and on footwear, consistent with anthropogenic dispersal of the organism. Increased levels of airborne C. gattii were detected during forestry and municipal activities such as wood chipping, the byproducts of which are frequently used in park landscaping. C. gattii dispersal by these mechanisms may be a useful model for other emerging pathogens. PMID:17370515

  7. Assessing the breast cancer risk distribution for women undergoing screening in British Columbia.

    PubMed

    Weisstock, Christina R; Rajapakshe, Rasika; Bitgood, Christabelle; McAvoy, Steven; Gordon, Paula B; Coldman, Andrew J; Parker, Brent A; Wilson, Christine

    2013-10-01

    Breast cancer risk estimations are both informative and useful at the population level, with many screening programs relying on these assessments to allocate resources such as breast MRI. This cross-sectional multicenter study attempts to quantify the breast cancer risk distribution for women between the ages of 40 to 79 years undergoing screening mammography in British Columbia (BC), Canada. The proportion of women at high breast cancer risk was estimated by surveying women enrolled in the Screening Mammography Program of British Columbia (SMPBC) for known breast cancer risk factors. Each respondent's 10-year risk was computed with both the Tyrer-Cuzick and Gail risk assessment models. The resulting risk distributions were evaluated using the guidelines from the National Institute for Health and Care Excellence (United Kingdom). Of the 4,266 women surveyed, 3.5% of women between the ages of 40 to 79 years were found to have a high 10-year risk of developing breast cancer using the Tyrer-Cuzick model (1.1% using the Gail model). When extrapolated to the screening population, it was estimated that 19,414 women in the SMPBC are considered to be at high breast cancer risk. These women may benefit from additional MRI screening; preliminary analysis suggests that 4 to 5 additional MRI machines would be required to screen these high-risk women. However, the use of different models and guidelines will modify the number of women qualifying for additional screening interventions, thus impacting the MRI resources required. The results of this project can now be used to inform decision-making groups about resource allocation for breast cancer screening in BC.

  8. Validation of self-reported diagnosis of diabetes in the 1946 British birth cohort.

    PubMed

    Pastorino, Silvia; Richards, Marcus; Hardy, Rebecca; Abington, Jane; Wills, Andrew; Kuh, Diana; Pierce, Mary

    2015-10-01

    The aim of this study was to validate self-reported diabetes and age at diagnosis among a sample of the British population, using general practitioners (GPs) as the reference standard. Using data from the Medical Research Council National Survey of Health and Development (NSHD), self-reported diabetes was determined either in response to a direct question at five follow-ups between 1977 and 2010, or from other self-reported medical information. A validation questionnaire was sent to the GP for all participants who reported a diagnosis of diabetes and gave permission to contact their GP (172). The validity of self-reported diabetes was assessed by calculating the percentage of self-reported diabetes cases that were confirmed by their GP, i.e. the positive predictive value (PPV). The difference between self-reported and GP-confirmed age at diagnosis was analysed with a Bland-Altman plot. Completed questionnaires were obtained from 157 GPs (91.2%). Of these, 149 confirmed their patient self-reported diabetes diagnosis (PPV=94.9%). Results were similar when self-reported diabetes was assessed by responses to direct questions only (PPV=95.4%). The average difference between self-reported and GP-reported age at diagnosis was 0.6 years (95% CI 0.2-1.1). We conclude that among the British population questionnaires are a valid method to assess GP-diagnosed diabetes, as measured by responses to a direct question or by patient-reported medical information.

  9. Measurement of biogenic hydrocarbon emissions from vegetation in the Lower Fraser Valley, British Columbia

    NASA Astrophysics Data System (ADS)

    Drewitt, G. B.; Curren, K.; Steyn, D. G.; Gillespie, T. J.; Niki, H.

    Biogenic volatile organic compounds (VOCs) participate in many chemical reactions in the atmosphere and in some cases, adversely affect air quality through increased production of photochemical ozone near urban sources of nitrogen oxides. In order to implement an effective control strategy, the relative role of these biogenic hydrocarbon emissions in producing ground-level ozone must be known. During the summers of 1995 and 1996, a field study was undertaken to determine fluxes of biogenic VOCs from both natural and agricultural surfaces in the Lower Fraser Valley located in southwestern British Columbia. Emissions from agricultural surfaces were measured using a flux gradient approach while emissions from the dominant tree species in the region were measured with a branch enclosure system. Results show very little biogenic VOC production from many agricultural crops such as pasture, Potatoes or Blueberries. Cranberries showed very high emissions during the summer of 1994 but failed to show similar results during the summer of 1995. Emissions of isoprene and monoterpenes from native tree species such as Western Red Cedar, Douglas Fir and Coastal Hemlock were quite low. Cottonwood trees on the other hand had fairly low emissions of monoterpenes but extremely high emissions of isoprene. Measurements provided here will be useful for improving our database of hydrocarbon emissions rates from vegetation for future emission inventories and model testing.

  10. The British Abortion Act (1967) and the interests of the foetus.

    PubMed

    Mavroforou, A; Michalodimitrakis, E

    2006-03-01

    This article examines ethical issues on the rights and interests of the unborn foetus, an issue that remains highly contentious. Furthermore, it attempts to investigate how well the British legislation fits with the foetus and pregnant woman's rights and interests. "Pro-life" and "pro-choice" groups have provided extensive arguments for and against. One important theoretical issue rests on whether foetuses are human beings in the moral sense, in which all human beings have full and equal moral rights. What constitutes personhood is a matter of moral decision and is not one of scientific fact and thus it consists of all persons, rather than all genetically human entities. It is persons who invent moral rights and who are capable of respecting them. Legislators in Britain have sidestepped the ethical debate on abortion by opting for the pragmatic course of permitting abortion in a limited range of circumstances and thus the Abortion Act 1967 has failed to address the status of the foetus, or indeed the rights of any of the parties concerned. Thus, although the Act supports the interests of the foetus capable of free existence by lowering the foetal age to 24 weeks after which termination is not permissible, the legislators have accepted that the rights of the woman outweigh those of the foetus and if a woman's own life or health is in danger then even a late abortion is the best choice.

  11. Thermal analysis of the failed equipment storage vault system

    SciTech Connect

    Jerrell, J.; Lee, S.Y.; Shadday, A.

    1995-07-01

    A storage facility for failed glass melters is required for radioactive operation of the Defense Waste Processing Facility (DWPF). It is currently proposed that the failed melters be stored in the Failed Equipment Storage Vaults (FESV`s) in S area. The FESV`s are underground reinforced concrete structures constructed in pairs, with adjacent vaults sharing a common wall. A failed melter is to be placed in a steel Melter Storage Box (MSB), sealed, and lowered into the vault. A concrete lid is then placed over the top of the FESV. Two melters will be placed within the FESV/MSB system, separated by the common wall. There is no forced ventilation within the vault so that the melter is passively cooled. Temperature profiles in the Failed Equipment Storage Vault Structures have been generated using the FLOW3D software to model heat conduction and convection within the FESV/MSB system. Due to complexities in modeling radiation with FLOW3D, P/THERMAL software has been used to model radiation using the conduction/convection temperature results from FLOW3D. The final conjugate model includes heat transfer by conduction, convection, and radiation to predict steady-state temperatures. Also, the FLOW3D software has been validated as required by the technical task request.

  12. Hepatitis B Awareness and Knowledge in Asian Communities in British Columbia

    PubMed Central

    Yau, Alan Hoi Lun; Ford, Jo-Ann; Kwan, Peter Wing Cheung; Chan, Jessica; Choo, Queenie; Kwong, Willie; Huang, Alan; Yoshida, Eric

    2016-01-01

    Background. Our study examined hepatitis B virus (HBV) awareness and knowledge in Asian communities in British Columbia (BC). Methods. A statistical random sample representation of Chinese, Korean, Filipino, South Asian, and Southeast Asian populations in Greater Vancouver was surveyed by telephone. Multiple logistic regression analysis was performed to identify predictors of HBV knowledge. Results. General awareness of HBV was reported in 78.8% (798/1013). HBV awareness was the highest in Chinese (89%) and Filipino (88%) populations and the lowest in the South Asian (56%) population. “Reasonable” knowledge of HBV was elicited in 76.8% (778/1013). Higher HBV knowledge was associated with younger age (p = 0.014), higher education (p < 0.0001), Chinese ethnicity (p < 0.0001), and use of media (p = 0.01) and Internet (p = 0.024) for health information. Compared to the Chinese (OR = 1.0) population, “reasonable” knowledge of HBV was lower in Korean (OR = 0.3, 95% CI: 0.1–0.5), Filipino (OR = 0.3, 95% CI: 0.2–0.6), South Asian (OR = 0.3, 95% CI: 0.2–0.4), and Southeast Asian (OR = 0.3, 95% CI: 0.1–0.6) populations. 54.8% (555/1013) felt that HBV education was inadequate and 80.1% (811/1013) preferred HBV education in their native languages. Conclusion. Compared to the Chinese population, other Asian communities in BC have lower HBV awareness and knowledge. Public education should target older and less educated and Korean, Filipino, South Asian, and Southeast Asian populations in their native languages via media and Internet. PMID:27446839

  13. Hepatitis B Awareness and Knowledge in Asian Communities in British Columbia.

    PubMed

    Yau, Alan Hoi Lun; Ford, Jo-Ann; Kwan, Peter Wing Cheung; Chan, Jessica; Choo, Queenie; Lee, Tim K; Kwong, Willie; Huang, Alan; Yoshida, Eric

    2016-01-01

    Background. Our study examined hepatitis B virus (HBV) awareness and knowledge in Asian communities in British Columbia (BC). Methods. A statistical random sample representation of Chinese, Korean, Filipino, South Asian, and Southeast Asian populations in Greater Vancouver was surveyed by telephone. Multiple logistic regression analysis was performed to identify predictors of HBV knowledge. Results. General awareness of HBV was reported in 78.8% (798/1013). HBV awareness was the highest in Chinese (89%) and Filipino (88%) populations and the lowest in the South Asian (56%) population. "Reasonable" knowledge of HBV was elicited in 76.8% (778/1013). Higher HBV knowledge was associated with younger age (p = 0.014), higher education (p < 0.0001), Chinese ethnicity (p < 0.0001), and use of media (p = 0.01) and Internet (p = 0.024) for health information. Compared to the Chinese (OR = 1.0) population, "reasonable" knowledge of HBV was lower in Korean (OR = 0.3, 95% CI: 0.1-0.5), Filipino (OR = 0.3, 95% CI: 0.2-0.6), South Asian (OR = 0.3, 95% CI: 0.2-0.4), and Southeast Asian (OR = 0.3, 95% CI: 0.1-0.6) populations. 54.8% (555/1013) felt that HBV education was inadequate and 80.1% (811/1013) preferred HBV education in their native languages. Conclusion. Compared to the Chinese population, other Asian communities in BC have lower HBV awareness and knowledge. Public education should target older and less educated and Korean, Filipino, South Asian, and Southeast Asian populations in their native languages via media and Internet.

  14. The use of seat belts on British motorways.

    PubMed Central

    Wyatt, J P; Richardson, J M

    1994-01-01

    Evidence demonstrating the advantages of seat belts in improving safety of road travel is overwhelming and has resulted in government legislation. This study was performed to investigate compliance with this legislation by fast-moving traffic on British motorways, for which no previous data exists. Analysis of seat belt use by 2564 travellers in 1526 cars in October 1992 revealed the following rates of use: drivers 98%; front passengers 96%; rear seat passengers with available belts 53%. The overall low rate of rear seat restraint use was seen in all age groups except babies. When the study was repeated 8 months later, the rates of restraint amongst 3910 travellers in 1881 cars had not increased. In view of the continuing heavy death toll on British motorways and roads, there is an obvious need for measures to improve rear seat belt use. This would be most appropriately achieved by both enforcing and publicizing the current legislation. PMID:8182674

  15. Medicare financing and redistribution in british columbia, 1992 and 2002.

    PubMed

    McGrail, Kimberlyn

    2007-05-01

    Equity in healthcare in British Columbia is defined as the provision of services based on need rather than ability to pay and a separation of contributions to financing from the use of services. Physician and hospital services in Canada are financed mainly through general tax revenues, and there is a perception that this financing is progressive. This paper uses Gini coefficients, concentration indexes and Kakwani indexes of progressivity to assess the progressivity of medicare financing in British Columbia in 1992 and 2002. It also measures the overall redistributive effect of medicare services, considering both contributions to financing and use of hospital and physician services. The conclusion is that medicare does redistribute across income groups, but this redistribution is the result solely of the positive correlation between health status and income; financing is nearly proportionate across income groups, but use is higher among lower-income groups. Informed public debate requires a better understanding of these concepts of equity.

  16. West Nile virus range expansion into British Columbia.

    PubMed

    Roth, David; Henry, Bonnie; Mak, Sunny; Fraser, Mieke; Taylor, Marsha; Li, Min; Cooper, Ken; Furnell, Allen; Wong, Quantine; Morshed, Muhammad

    2010-08-01

    In 2009, an expansion of West Nile virus (WNV) into the Canadian province of British Columbia was detected. Two locally acquired cases of infection in humans and 3 cases of infection in horses were detected by ELISA and plaque-reduction neutralization tests. Ten positive mosquito pools were detected by reverse transcription PCR. Most WNV activity in British Columbia in 2009 occurred in the hot and dry southern Okanagan Valley. Virus establishment and amplification in this region was likely facilitated by above average nightly temperatures and a rapid accumulation of degree-days in late summer. Estimated exposure dates for humans and initial detection of WNV-positive mosquitoes occurred concurrently with a late summer increase in Culex tarsalis mosquitoes (which spread western equine encephalitis) in the southern Okanagan Valley. The conditions present during this range expansion suggest that temperature and Cx. tarsalis mosquito abundance may be limiting factors for WNV transmission in this portion of the Pacific Northwest.

  17. The use of seat belts on British motorways.

    PubMed

    Wyatt, J P; Richardson, J M

    1994-04-01

    Evidence demonstrating the advantages of seat belts in improving safety of road travel is overwhelming and has resulted in government legislation. This study was performed to investigate compliance with this legislation by fast-moving traffic on British motorways, for which no previous data exists. Analysis of seat belt use by 2564 travellers in 1526 cars in October 1992 revealed the following rates of use: drivers 98%; front passengers 96%; rear seat passengers with available belts 53%. The overall low rate of rear seat restraint use was seen in all age groups except babies. When the study was repeated 8 months later, the rates of restraint amongst 3910 travellers in 1881 cars had not increased. In view of the continuing heavy death toll on British motorways and roads, there is an obvious need for measures to improve rear seat belt use. This would be most appropriately achieved by both enforcing and publicizing the current legislation.

  18. The Hypersensitivity of Horses to Culicoides Bites in British Columbia

    PubMed Central

    Anderson, Gail S.; Belton, Peter; Kleider, Nicholas

    1988-01-01

    Culicoides hypersensitivity is a chronic, recurrent, seasonal dermatitis of horses that has a worldwide distribution, but has only recently been reported in Canada. It is characterized by intense pruritus resulting in lesions associated with self-induced trauma. A survey of veterinarians and horse-owners in British Columbia showed no differences in susceptibility due to the sex, color, breed, or height of the horses. The prevalence of the disease in the 209 horses surveyed was 26%. Horses sharing the same pasture could be unaffected. The disease was reported primarily from southwestern British Columbia; it occurred between April and October and usually affected the ventral midline, mane, and tail. Horses were generally less than nine years old when the clinical signs first appeared ([unk]=5.9 yr). Culicoides hypersensitivity was common in the lineage of several affected horses, possibly indicating a genetic susceptibility. Most cases were severe enough to require veterinary attention and some horses were euthanized. PMID:17423117

  19. Application of the British Gas/Lurgi slagging gasifier

    SciTech Connect

    Thompson, B.H.; Lacey, J.A.; Herbert, P.K.; Vierrath, H.E.

    1985-01-01

    British Gas Lurgi slagging gasification and its status of commercial availability are presented. Two important cases for the application of slagging gasification are discussed in some detail: integrated gasification combined cycle (IGCC) power generation, and production of hydrogen from petroleum coke. Cost figures are presented for power generation and hydrogen production. Special attention is given to both present and the more stringent environmental regulations expected in the future.

  20. Are you British or Muslim; Can You be Both?

    DTIC Science & Technology

    2009-05-21

    democracy, the English language, Shakespeare . But this does little to answer the question of a British identity. The Telegraph newspaper and YouGov.com set...Advanced Studies Press, 2002), 185. 52 William J. Clinton, ―Remarks to the University of California San Diego Commencement Ceremony in La Jolla...Alone, 90. 71 Renshon, 83. 72 William Pfaff, ―Why France Still Insists on Cultural Assimilation: Head Scarves,‖ International Herald Tribune

  1. Remote sensing education at the University of British Columbia

    NASA Technical Reports Server (NTRS)

    Murtha, P. A.

    1981-01-01

    The development, current status, and organization of the University of British Columbia's interdisciplinary graduate program in remote sensing are described. Specialized programs are tailored to meet student's needs and interest and can range from the theoretical development of technology (sensor development, modelling, and computer analysis) to specialized application of remote sensing in resource analysis such as the determination of vegetation damage, land classification, and land use. The courses and faculty members are listed.

  2. Arms Control and British and French Nuclear Forces.

    DTIC Science & Technology

    1987-12-01

    no doubt on the American nuclear guarantee. On the contrary, the British borrowed the French concept of a "second nuclear decision center " as...concept of alternate decision making centers as a rationale for independent deterrent capabilities argues that by having more than one alliance...debate has been rather unique in that it has centered on the question of retention or abdication of an independent dcterrent capability, rather than on

  3. Strategic Factors Influencing the British and American Empires

    DTIC Science & Technology

    2003-04-07

    for the advancement of civilization and a major contribution to world peace. It was the faith if many ardent free traders that people who traded...conviction that he was an instrument for the bringing of civilization to those who stood most direly in need.43 Thus, there emerged during the nineteenth...especially after the Indian Mutiny of 1856), an increasing British military presence was required, followed by the need for greater civil control by the

  4. Soviet Perspectives on British Security Policy: A Reader

    DTIC Science & Technology

    1986-10-01

    development and policies, on Britain’s role in the Euromissile -1- deployments of the first half of the 1980s , and on the costs and benefits to Britain of such...modernization in the late 1980s and early 1990s, with noteworthy treatments of nuclear force modernization, chemi- cal weapons, and Britain’s expanding...missiles in Western Europe—including on British territory; and in 1980 it declared its intention to acquire the latest strategic weapon system, the

  5. British media attacks on homeopathy: are they justified?

    PubMed

    Vithoulkas, George

    2008-04-01

    Homeopathy is being attacked by the British media. These attacks draw support from irresponsible and unjustified claims by certain teachers of homeopathy. Such claims include the use of 'dream' and 'imaginative' methods for provings. For prescribing some such teachers attempt to replace the laborious process of matching symptom picture and remedy with spurious theories based on 'signatures', sensations and other methods. Other irresponsible claims have also been made. These "new ideas" risk destroying the principles, theory, and practice of homeopathy.

  6. Strategic Dissonance: British Middle East Command in World War II

    DTIC Science & Technology

    2014-05-22

    Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas AY 2014-001 Approved for Public Release...tactical operations against the advice of the military commander, resulted in failure to win the most important campaign. The victorious campaigns...undertaken against the advice of the military commander, proved to have no strategic value, and may have ultimately cost the British forces far more than

  7. Extensional duplex in the Purcell Mountains of southeastern British Columbia

    SciTech Connect

    Root, K.G. )

    1990-05-01

    An extensional duplex consisting of fault-bounded blocks (horses) located between how-angle normal faults is exposed in Proterozoic strata in the Purcell Mountains of British Columbia, Canada. This is one of the first documented extensional duplexes, and it is geometrically and kinematically analogous to duplexes developed in contractional and strike-slip fault systems. The duplex formed within an extensional fault with a ramp and flat geometry when horses were sliced from the ramp and transported within the fault system.

  8. Arts and the Perceived Quality of Life in British Columbia

    ERIC Educational Resources Information Center

    Michalos, Alex C.; Kahlke, P. Maurine

    2010-01-01

    The aims of this investigation were (1) to measure the impact of arts-related activities on the perceived quality of life of a representative sample of British Columbians aged 18 years or more in the spring of 2007, and (2) to compare the findings of this study with those of a sample of 1,027 adults drawn from five B.C. communities (Comox Valley,…

  9. Understanding British Strategic Failure in America: 1780-1783

    DTIC Science & Technology

    2012-03-17

    New York, Charleston, and Savanna.53 Similarly, in late December, the Governor of New York, James Robertson , pleaded for reinforcements and the...See for example, William Seymour and W. F. N. Watson, The Price of Folly: British Blunders in the War of American Independence. (London: Brassey’s...29 52 Higginbotham, The War of American Independence, 370-374. 53 Black, War for America, 236. 54 Royal Governor of New York, James Robertson

  10. Challenges of Investigating Community Outbreaks of Cyclosporiasis, British Columbia, Canada

    PubMed Central

    Shah, Lena; Ellis, Andrea; Ong, Corinne; Shyng, Sion; LeBlanc, Linda

    2009-01-01

    Investigations of community outbreaks of cyclosporiasis are challenged by case-patients’ poor recall of exposure resulting from lags in detection and the stealthy nature of food vehicles. We combined multiple techniques, including early consultation with food regulators, traceback of suspected items, and grocery store loyalty card records, to identify a single vehicle for a cyclosporiasis outbreak in British Columbia, Canada, in 2007. PMID:19751593

  11. Failed MTR Fuel Element Detect in a Sipping Tests

    SciTech Connect

    Zeituni, C.A.; Terremoto, L.A.A.; da Silva, J.E.R.

    2004-10-06

    This work describes sipping tests performed on Material Testing Reactor (MTR) fuel elements of the IEA-R1 research reactor, in order to find out which one failed in the core during a routine operation. Radioactive iodine isotopes {sup 131}I and {sup 133}I, employed as failure monitors, were detected in samples corresponding to the failed fuel element. The specific activity of each sample, as well as the average leaking rate, were measured for {sup 137}Cs. The nuclear fuels U{sub 3}O{sub 8} - Al dispersion and U - Al alloy were compared concerning their measured average leaking rates of {sup 137}Cs.

  12. Perceptions of Quality and Approaches to Studying in Higher Education: A Comparative Study of Chinese and British Postgraduate Students at Six British Business Schools

    ERIC Educational Resources Information Center

    Sun, Haoda; Richardson, John T. E.

    2012-01-01

    Previous studies of "the Chinese learner" have confounded the effects of culture and context or have used heterogeneous samples of students. In this study, 134 British students and 207 students from mainland China following 1-year postgraduate programmes at six British business schools completed the Course Experience Questionnaire (CEQ)…

  13. Trust and British Gas partner in EPC scheme.

    PubMed

    Bevan, Patrick

    2015-02-01

    In late August last year the St George's Healthcare NHS Trust in south-west London signed what the Trust's Estates and Facilities team described as 'a historic partnership' with British Gas for a £12 m Energy Performance Contract energy reduction scheme--via which the energy company has guaranteed to deliver £1.1 m in annual savings over the next 15 years. The agreement will see British Gas replace four 35-year-old gas-powered steam boilers and an ageing CHP plant in the boiler house at the Trust's main acute facility, the StGeorge's Hospital in Tooting, and upgrade some of the associated infrastructure. British Gas will also maintain the new plant to ensure that the projected savings are achieved while the Trust owns the new assets. The Trust should gain financially--via lower energy costs and carbon emissions, while estates personnel will be better able to complete the many other estate maintenance issues that would otherwise be contracted out at one of London's biggest acute hospitals.

  14. Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus neoformans.

    PubMed

    Cheng, Po-Yan; Sham, Anita; Kronstad, James W

    2009-10-01

    The fungal pathogen Cryptococcus neoformans causes approximately one million cases of cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is responsible for a much smaller number of cases, but these often occur in immunocompetent people. In fact, C. gattii has emerged in the last decade as the frequent cause of cryptococcosis in otherwise healthy people in British Columbia. We analyzed the immune responses elicited by three C. gattii strains and one C. neoformans strain in mice as a first step toward understanding why C. gattii is able to cause disease in immunocompetent hosts. The C. gattii strains all induced a less protective inflammatory response in C57BL/6 mice by inhibiting or failing to provoke the migration of neutrophils to sites of infection. The C. gattii strains also failed to elicit the production of protective cytokines, such as tumor necrosis factor alpha, compared to the ability of the C. neoformans strain. Despite these differences, the strain representing the major outbreak genotype from British Columbia showed a virulence equivalent to that of the C. neoformans strain, while two other C. gattii strains had reduced virulence. Taken together, our results indicate that C. gattii strains thrive in immunocompetent hosts by evading or suppressing the protective immune responses that normally limit the progression of disease caused by C. neoformans.

  15. British Logistics Challenges in the American Revolution: How Logistics was a Critical Vulnerability in the British Effort to Ensure Victor

    DTIC Science & Technology

    2012-05-01

    cultural differences when planning operations. I greatly appreciate his patience as I learned how to interject my thoughts into classroom discussions. I...British were still sending out approximately four hundred ships laden with supplies for its military forces in America. Year in and year out, many supply...against 7 Philadelphia. "Howe’s voyage was a nightmare. It consumed thirty-two days, four times what had been anticipated, and twice as long as

  16. Attitudes towards people with intellectual disabilities: a comparison of young people from British South Asian and White British backgrounds.

    PubMed

    Sheridan, Joel; Scior, Katrina

    2013-04-01

    Research with South Asian families of individuals with intellectual disabilities (ID) suggests an increased fear of stigma and isolation from the community. Evidence on attitudes towards ID among the wider community is very limited and was the focus of the present study. Responses were collected from 737 college students aged 16-19 using the Community Living Attitudes Scale-ID version. Results indicated that British South Asians (n=355) were less in favour of the social inclusion of people with ID than White British young people (n=382). British South Asian adolescents were more likely to hold the view that people with ID should be sheltered and not empowered. It is proposed that future inclusion policies integrate ethnic minority views whose religious and cultural values do not always conform to the core values of social inclusion policies. It is also proposed that culturally specific school based interventions could be introduced with the aims of decreasing stigma and fostering attitudes in line with the aims of normalisation.

  17. Plasma Brightenings in a Failed Solar Filament Eruption

    NASA Astrophysics Data System (ADS)

    Li, Y.; Ding, M. D.

    2017-03-01

    Failed filament eruptions are solar eruptions that are not associated with coronal mass ejections. In a failed filament eruption, the filament materials usually show some ascending and falling motions as well as generating bright EUV emissions. Here we report a failed filament eruption (SOL2016-07-22) that occurred in a quiet-Sun region observed by the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory. In this event, the filament spreads out but gets confined by the surrounding magnetic field. When interacting with the ambient magnetic field, the filament material brightens up and flows along the magnetic field lines through the corona to the chromosphere. We find that some materials slide down along the lifting magnetic structure containing the filament and impact the chromosphere, and through kinetic energy dissipation, cause two ribbon-like brightenings in a wide temperature range. There is evidence suggesting that magnetic reconnection occurs between the filament magnetic structure and the surrounding magnetic fields where filament plasma is heated to coronal temperatures. In addition, thread-like brightenings show up on top of the erupting magnetic fields at low temperatures, which might be produced by an energy imbalance from a fast drop of radiative cooling due to plasma rarefaction. Thus, this single event of a failed filament eruption shows the existence of a variety of plasma brightenings that may be caused by completely different heating mechanisms.

  18. Understanding and Working with "Failed Communication" in Telecollaborative Exchanges

    ERIC Educational Resources Information Center

    O'Dowd, Robert; Ritter, Markus

    2006-01-01

    It is by now well established that telecollaborative exchanges frequently end in "failed communication" and do not automatically bring about successful negotiation of meaning between the learners. Instead, the intended pedagogic and linguistic aims of online interaction are repeatedly missed, and projects may end in low levels of participation,…

  19. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... procedure for aflatoxin. If inshell rework is selected as a remedy to meet the aflatoxin regulations of this... product shall be reported to the committee. The reworked lot shall be sampled and tested for aflatoxin as... the lot has been reworked and tested, it fails the aflatoxin test for a second time, the lot may...

  20. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... procedure for aflatoxin. If inshell rework is selected as a remedy to meet the aflatoxin regulations of this... product shall be reported to the committee. The reworked lot shall be sampled and tested for aflatoxin as... the lot has been reworked and tested, it fails the aflatoxin test for a second time, the lot may...

  1. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... procedure for aflatoxin. If inshell rework is selected as a remedy to meet the aflatoxin regulations of this... product shall be reported to the committee. The reworked lot shall be sampled and tested for aflatoxin as... the lot has been reworked and tested, it fails the aflatoxin test for a second time, the lot may...

  2. "It's All Human Error!": When a School Science Experiment Fails

    ERIC Educational Resources Information Center

    Viechnicki, Gail Brendel; Kuipers, Joel

    2006-01-01

    This paper traces the sophisticated negotiations to re-inscribe the authority of Nature when a school science experiment fails during the enactment of a highly rated science curriculum unit. Drawing on transcriptions from classroom videotapes, we identify and describe four primary patterns of interaction that characterize this process, arguing…

  3. Ballooning osteolysis in 71 failed total ankle arthroplasties

    PubMed Central

    Singh, Gurpal; Reichard, Theresa; Hameister, Rita; Awiszus, Friedemann; Schenk, Katja; Feuerstein, Bernd; Roessner, Albert; Lohmann, Christoph

    2016-01-01

    Background and purpose Aseptic loosening is a major cause of failure in total ankle arthroplasty (TAA). In contrast to other total joint replacements, large periarticular cysts (ballooning osteolysis) have frequently been observed in this context. We investigated periprosthetic tissue responses in failed TAA, and performed an element analysis of retrieved tissues in failed TAA. Patients and methods The study cohort consisted of 71 patients undergoing revision surgery for failed TAA, all with hydroxyapatite-coated implants. In addition, 5 patients undergoing primary TAA served as a control group. Radiologically, patients were classified into those with ballooning osteolysis and those without, according to defined criteria. Histomorphometric, immunohistochemical, and elemental analysis of tissues was performed. Von Kossa staining and digital microscopy was performed on all tissue samples. Results Patients without ballooning osteolysis showed a generally higher expression of lymphocytes, and CD3+, CD11c+, CD20+, and CD68+ cells in a perivascular distribution, compared to diffuse expression. The odds of having ballooning osteolysis was 300 times higher in patients with calcium content >0.5 mg/g in periprosthetic tissue than in patients with calcium content ≤0.5 mg/g (p < 0.001). Interpretation There have been very few studies investigating the pathomechanisms of failed TAA and the cause-effect nature of ballooning osteolysis in this context. Our data suggest that the hydroxyapatite coating of the implant may be a contributory factor. PMID:27196532

  4. Why Young People Fail To Get and Hold Jobs.

    ERIC Educational Resources Information Center

    New York State Dept. of Labor, Albany.

    This booklet provides advice to young people seeking their first jobs on how to avoid the pitfalls that have caused others to lose jobs or fail to be hired. Topics discussed in short, one-page sections include appearance, attitude and behavior, ignorance of labor market facts, misrepresentation, sensitivity about a physical defect, unrealistic…

  5. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be...

  6. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be...

  7. Management of adults with prior failed hypospadias surgery

    PubMed Central

    Craig, James R.; Wallis, Chad; Brant, William O.; Hotaling, James M.

    2014-01-01

    Hypospadias is one of the most prevalent anomalies of the male genitalia. Contemporary hypospadias repair is very successful, but patients that have the surgery fail often require multiple surgeries throughout their life. Complications from failed hypospadias repairs have a significant impact on patients both psychologically and physically. Failed hypospadias repair encompasses a spectrum of problems that include hypospadias recurrence with an ectopic meatus, urethral fistula, urethral stricture, and ventral penile curvature. Repairs of hypospadias complications can be challenging due to the poor quality of surrounding tissue from disruption of normal vasculature in the re-operative field associated with the underlying disorder. One of the most challenging issues is dealing with urethral strictures. There have been multiple methods described at repairs of these in both a single stage and multiple staged procedures. Particular attention has been directed towards applications of grafts due to worse outcomes with flaps. Buccal mucosa has emerged as the leading graft material in staged repairs. When counseling patients with failed hypospadias it is important to discuss the expected outcome as repairs directed towards a terminally positioned meatus with a straight phallus may require multiple surgeries due to post-operative complications as well as the necessity of proceeding in a staged approach. PMID:26816767

  8. When Consensus Decision-Making Fails: A Case Study.

    ERIC Educational Resources Information Center

    Savage, Grant T.

    Habermas's theory of dialogue was used to evaluate the process of decision making that occurred in a labor-management committee's meeting to discuss flextime. The study attempted to determine why, at that meeting, the committee's consensus process of decision making failed. W.R. Bion's theory of unconscious group motives was also used to…

  9. 7 CFR 983.152 - Failed lots/rework procedure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Failed lots/rework procedure. 983.152 Section 983.152 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN...

  10. 7 CFR 983.52 - Failed lots/rework procedure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Failed lots/rework procedure. 983.52 Section 983.52 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN...

  11. Solutions for Failing High Schools: Converging Visions and Promising Models.

    ERIC Educational Resources Information Center

    Legters, Nettie; Balfanz, Robert; McPartland, James

    Promising solutions to the failings of traditional comprehensive high schools were reviewed to identify basic principles and strategies for improving high schools nationwide. Selected research studies, policy documents, and promising high school programs were reviewed. The review revealed the following principles for helping high schools better…

  12. Failing Boys! Beyond Crisis, Moral Panic and Limiting Stereotypes

    ERIC Educational Resources Information Center

    Martino, Wayne

    2011-01-01

    For some time now, school boards, Ministries of Education, and the popular media have been expressing concerns about failing boys and how best to meet their needs, framing these concerns in terms of a crisis in which boys are the "new disadvantaged". This perspective does not provide an accurate representation of the problem and, in fact, detracts…

  13. Improving Charter School Accountability: The Challenge of Closing Failing Schools

    ERIC Educational Resources Information Center

    Osborne, David

    2012-01-01

    Today some 5,600 charter schools are in operation, with more than two million students. Some critics persist in a fruitless argument that these schools have failed, despite a mountain of evidence to the contrary. But regardless of your opinion about them, charter schools are here to stay. Those concerned about public education should quit debating…

  14. Depressed phosphatidic acid-induced contractile activity of failing cardiomyocytes.

    PubMed

    Tappia, Paramjit S; Maddaford, Thane G; Hurtado, Cecilia; Panagia, Vincenzo; Pierce, Grant N

    2003-01-10

    The effects of phosphatidic acid (PA), a known inotropic agent, on Ca(2+) transients and contractile activity of cardiomyocytes in congestive heart failure (CHF) due to myocardial infarction were examined. In control cells, PA induced a significant increase (25%) in active cell shortening and Ca(2+) transients. The phospholipase C (PLC) inhibitor, 2-nitro-4-carboxyphenyl N,N-diphenylcarbonate, blocked the positive inotropic action induced by PA, indicating that PA induces an increase in contractile activity and Ca(2+) transients through stimulation of PLC. Conversely, in failing cardiomyocytes there was a loss of PA-induced increase in active cell shortening and Ca(2+) transients. PA did not alter resting cell length. Both diastolic and systolic [Ca(2+)] were significantly elevated in the failing cardiomyocytes. In vitro assessment of the cardiac sarcolemmal (SL) PLC activity revealed that the impaired failing cardiomyocyte response to PA was associated with a diminished stimulation of SL PLC activity by PA. Our results identify an important defect in the PA-PLC signaling pathway in failing cardiomyocytes, which may have significant implications for the depressed contractile function during CHF.

  15. 78 FR 4349 - Records of Failed Insured Depository Institutions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... of the institution but also materials that have no relevance to its business, or which lack evidentiary value and would not ordinarily be considered ``records.'' In addition, advances in information... obtains from a failed insured depository institution, regardless of its significance or evidentiary...

  16. Majority-voted logic fail-sense circuit

    NASA Technical Reports Server (NTRS)

    Mclyman, W. T.

    1977-01-01

    Fail-sense circuit has majority-voted logic component which receives three error voltage signals that are sensed at single point by three error amplifiers. If transistor shorts, only one signal is required to operate; if transistor opens, two signals are required.

  17. Why the Merit Pay System Failed in the Federal Government.

    ERIC Educational Resources Information Center

    Silverman, Buddy Robert S.

    1983-01-01

    Discusses the implementation of the merit pay system in the federal government and the ten unsurmountable problems that caused it to fail; i.e., unintended statutory provisions, open-ended regulations, novice technical assistance, drifting implementation policies, administrative errors, complicated systems, inconsistent employee treatment,…

  18. Preventing Suicide: A Mission Too Big to Fail

    DTIC Science & Technology

    2013-03-01

    Soldier Fitness Program Evaluation, Report #3,” 23. 129 Ibid. 130 Kerry L . Knox and Robert M . Bossarte, “Suicide Prevention for Veterans and Active Duty...Preventing Suicide: A Mission Too Big to Fail by Ms. Gloria Duck Lieutenant Colonel Timothy Holman Ms. Jennifer Jessup ...Lieutenant Colonel Timothy Holman United States Army Ms. Jennifer Jessup Department of Veterans Affairs Civilian Colonel Keith

  19. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be...

  20. What is the optimal rate of failed extubation?

    PubMed Central

    2012-01-01

    Failed extubation (FE), defined as reintubation 48 or 72 hours after planned extubation, occurs in a significant percentage of patients and is associated with a substantial burden of morbidity and mortality. This commentary reviews the literature describing FE rates and the clinical consequences of FE and proposes an 'optimal' rate of FE as well as avenues for future research. PMID:22356725

  1. Public health in interwar England and Wales: did it fail?

    PubMed Central

    Gorsky, Martin

    2008-01-01

    British historians initially saw the interwar period as a «golden age» for public health in local government, with unprecedented preventive and curative powers wielded by Medical Officers of Health (MOsH). In the 1980s Lewis and Webster challenged this reading, arguing that MOsH were overstretched, neglectful of their «watchdog» role and incapable of formulating a new philosophy of preventive medicine. The article first details this critique, then reappraises it in the light of recent demographic work. It then provides a case study of public health administration in South-West England. Its conclusion is that some elements of the Lewis/Webster case now deserve to be revised. PMID:19230339

  2. Abandoned Ideology: How the Iranian Revolution Failed Islamic Economics and Embraced Populism

    DTIC Science & Technology

    2010-09-01

    Iranian revolution had an economic motivation. To the Islamist, it is not about the price of watermelons .14 The motivations that led to the rise of...man unconcerned with the price of watermelons was similarly unconcerned with the economic factors affecting the price of the watermelon in the first...about the price of watermelons .41 The motivations that led to the rise of Islamism in general also affected the growth of Islamic economics. As

  3. Failure in Campaign Design: The British Defeat at New Orleans December 1814 - January 1814

    DTIC Science & Technology

    2012-05-07

    have on unifying the isolated Louisiana Territory and the gulf coast region against any British efforts to control New Orleans and the Mississippi... region . The British realized that the American control of this area was not secure and wanted to capitalize on this weakness by mounting a campaign...States as the British promised an Indian Territory to be created west of the Appalachian Mountains. After the defeat of the Creeks by Jackson, the

  4. Traumatic work related mortality among seafarers employed in British merchant shipping, 1976–2002

    PubMed Central

    Roberts, S; Marlow, P

    2005-01-01

    Aims: To establish the causes and circumstances of all traumatic work related deaths among seafarers who were employed in British merchant shipping from 1976 to 2002, and to assess whether seafaring is still a hazardous occupation as well as a high risk occupation for suicide. Methods: A longitudinal study of occupational mortality, based on official mortality files, with a population of 1 136 427 seafarer-years at risk. Results: Of 835 traumatic work related deaths, 564 were caused by accidents, 55 by suicide, 17 by homicide, and 14 by drug or alcohol poisoning. The circumstances in which the other 185 deaths occurred, including 178 seafarers who disappeared at sea or were found drowned, were undetermined. The mortality rate for 530 fatal accidents that occurred at the workplace from 1976 to 2002, 46.6 per 100 000 seafarer-years, was 27.8 times higher than in the general workforce in Great Britain during the same time period. The fatal accident rate declined sharply since the 1970s, but the relative risk of a fatal accident was 16.0 in 1996–2002. There was no reduction in the suicide rate, which was comparable to that in most high risk occupations in Britain, from 1976 to 1995; but a decline since 1995. Conclusions: Although there was a large decline in the fatal accident rate in British shipping, compared to the general workforce, seafaring has remained a hazardous occupation. Further prevention should focus on improvements in safety awareness among seafarers and shipping companies, reductions in hazardous working practices, and improvements in care for seafarers at risk of suicide. PMID:15723882

  5. Modelling Future Coronary Heart Disease Mortality to 2030 in the British Isles

    PubMed Central

    Hughes, John; Kabir, Zubair; Bennett, Kathleen; Hotchkiss, Joel W.; Kee, Frank; Leyland, Alastair H.; Davies, Carolyn; Bandosz, Piotr; Guzman-Castillo, Maria; O’Flaherty, Martin; Capewell, Simon; Critchley, Julia

    2015-01-01

    Objective Despite rapid declines over the last two decades, coronary heart disease (CHD) mortality rates in the British Isles are still amongst the highest in Europe. This study uses a modelling approach to compare the potential impact of future risk factor scenarios relating to smoking and physical activity levels, dietary salt and saturated fat intakes on future CHD mortality in three countries: Northern Ireland (NI), Republic of Ireland (RoI) and Scotland. Methods CHD mortality models previously developed and validated in each country were extended to predict potential reductions in CHD mortality from 2010 (baseline year) to 2030. Risk factor trends data from recent surveys at baseline were used to model alternative future risk factor scenarios: Absolute decreases in (i) smoking prevalence and (ii) physical inactivity rates of up to 15% by 2030; relative decreases in (iii) dietary salt intake of up to 30% by 2030 and (iv) dietary saturated fat of up to 6% by 2030. Probabilistic sensitivity analyses were then conducted. Results Projected populations in 2030 were 1.3, 3.4 and 3.9 million in NI, RoI and Scotland respectively (adults aged 25–84). In 2030: assuming recent declining mortality trends continue: 15% absolute reductions in smoking could decrease CHD deaths by 5.8–7.2%. 15% absolute reductions in physical inactivity levels could decrease CHD deaths by 3.1–3.6%. Relative reductions in salt intake of 30% could decrease CHD deaths by 5.2–5.6% and a 6% reduction in saturated fat intake might decrease CHD deaths by some 7.8–9.0%. These projections remained stable under a wide range of sensitivity analyses. Conclusions Feasible reductions in four cardiovascular risk factors (already achieved elsewhere) could substantially reduce future coronary deaths. More aggressive polices are therefore needed in the British Isles to control tobacco, promote healthy food and increase physical activity. PMID:26422012

  6. Trends in AIDS incidence and AIDS-related mortality in British Columbia between 1981 and 2013

    PubMed Central

    Lima, Viviane D.; Lourenço, Lillian; Yip, Benita; Hogg, Robert S.; Phillips, Peter; Montaner, Julio S.G.

    2015-01-01

    Background Appropriate use of highly active antiretroviral therapy (HAART) can markedly decrease the risk of progression to acquired immunodeficiency syndrome (AIDS) and of premature mortality. We aimed to characterize the trends between 1981 and 2013 in AIDS-defining illnesses (ADIs) and in the number AIDS-related deaths in British Columbia (BC), Canada. Methods We included data of 3550 HIV-positive individuals, aged 19 years or older, from different administrative databases in BC. We estimated the relative risk of developing an ADI over time using a Negative Binomial model, and we investigated trends in the percentage of all deaths associated with AIDS using generalized additive models. Findings The number of ADIs has decreased dramatically to its lowest level in 2013. The peak of the AIDS epidemic in BC happened in 1994 with 696 ADIs being reported (rate 42 ADIs per 100 person-years). Since 1997, the number of ADIs decreased from 253 (rate 7 per 100 person-years) to 84 cases in 2013 (rate 1 per 100 person-years) (p-value equals to zero for the trend in the number of ADIs). We have also shown that out of 22 ADIs considered, only PCP maintained its prominent ranking (albeit with much reduced overall prevalence). Finally, we observed that over time very few deaths were related to AIDS-related causes, especially in the most recent years. Interpretation We showed that the number of new ADIs and AIDS-related mortality have been decreasing rapidly over time in BC. These results provide further evidence that integrated comprehensive free programs that facilitate testing, and deliver treatment and care to this population can be effective in markedly decreasing AIDS-related morbidity and mortality, thus suggesting that controlling and eventually ending AIDS is possible. Funding The British Columbia Ministry of Health, the US National Institutes of Health, the US National Institute on Drug Abuse, the Canadian Institutes of Health Research, and the Michael Institute for

  7. Assessing size and strength of the clavicle for its usefulness for sex estimation in a British medieval sample.

    PubMed

    Atterton, Thomas; De Groote, Isabelle; Eliopoulos, Constantine

    2016-10-01

    The construction of the biological profile from human skeletal remains is the foundation of anthropological examination. However, remains may be fragmentary and the elements usually employed, such as the pelvis and skull, are not available. The clavicle has been successfully used for sex estimation in samples from Iran and Greece. In the present study, the aim was to test the suitability of the measurements used in those previous studies on a British Medieval population. In addition, the project tested whether discrimination between sexes was due to size or clavicular strength. The sample consisted of 23 females and 25 males of pre-determined sex from two medieval collections: Poulton and Gloucester. Six measurements were taken using an osteometric board, sliding calipers and graduated tape. In addition, putty rings and bi-planar radiographs were made and robusticity measures calculated. The resulting variables were used in stepwise discriminant analyses. The linear measurements allowed correct sex classification in 89.6% of all individuals. This demonstrates the applicability of the clavicle for sex estimation in British populations. The most powerful discriminant factor was maximum clavicular length and the best combination of factors was maximum clavicular length and circumference. This result is similar to that obtained by other studies. To further investigate the extent of sexual dimorphism of the clavicle, the biomechanical properties of the polar second moment of area J and the ratio of maximum to minimum bending rigidity are included in the analysis. These were found to have little influence when entered into the discriminant function analysis.

  8. A Powerful Protector of the Japanese People: The History of the Japanese Hospital in Steveston, British Columbia, Canada,18961942.

    PubMed

    Vandenberg, Helen

    2017-01-01

    From 1896 to 1942, a Japanese hospital operated in the village of Steveston, British Columbia, Canada. For the first 4 years, Japanese Methodist missionaries utilized a small mission building as a makeshift hospital, until a larger institution was constructed by the local Japanese Fishermen's Association in 1900. The hospital operated until the Japanese internment, after the attack on Pearl Harbor during World War II. This study offers important commentary about the relationships between health, hospitals, and race in British Columbia during a period of increased immigration and economic upheaval. From the unique perspective of Japanese leaders, this study provides new insight about how Japanese populations negotiated hospital care, despite a context of severe racial discrimination. Japanese populations utilized Christianization, fishing expertise, and hospital work to garner more equitable access to opportunities and resources. This study demonstrates that in addition to providing medical treatment, training grounds for health-care workers, and safe refuge for the sick, hospitals played a significant role in confronting broader racialized inequities in Canada's past.

  9. Sex determination from the occipital condyle: discriminant function analysis in an eighteenth and nineteenth century British sample.

    PubMed

    Gapert, René; Black, Sue; Last, Jason

    2009-04-01

    Fragmentary human remains compromised by different types of inhumation, or physical insults such as explosions, fires, and mutilations may frustrate the use of traditional morphognostic sex determination methods. The basicranium is protected by a large soft tissue mass comprising muscle, tendon, and ligaments. As such, the occipital region may prove useful for sex identification in cases of significantly fragmented remains. The aims of this paper are to (1) evaluate sexual dimorphism in British cranial bases by manually recorded unilateral and bilateral condylar length and width as well as intercondylar measurements and (2) develop discriminant functions for sex determination for this cranial sample. The crania selected for this study are part of the 18th-19th century documented skeletal collection of St. Bride's Church, Fleet Street, London. Adult human skulls (n = 146; male75/female71) were measured to derive statistical functions. Results indicated that expression of sexual dimorphism in the occipital condylar region within the St. Bride's population is demonstrable but low. Crossvalidated classification accuracy ranged between 69.2 and 76.7%, and sex bias ranged from 0.3 to 9.7%. Therefore, the use of discriminant functions derived from occipital condyles, especially in British skeletal populations, should only be considered in cases of fragmented cranial bases when no other morphognostic or morphometric method can be utilized for sex determination.

  10. Causes and consequences of failed adaptation to biological invasions: the role of ecological constraints.

    PubMed

    Lau, Jennifer A; terHorst, Casey P

    2015-05-01

    Biological invasions are a major challenge to native communities and have the potential to exert strong selection on native populations. As a result, native taxa may adapt to the presence of invaders through increased competitive ability, increased antipredator defences or altered morphologies that may limit encounters with toxic prey. Yet, in some cases, species may fail to adapt to biological invasions. Many challenges to adaptation arise because biological invasions occur in complex species-rich communities in spatially and temporally variable environments. Here, we review these 'ecological' constraints on adaptation, focusing on the complications that arise from the need to simultaneously adapt to multiple biotic agents and from temporal and spatial variation in both selection and demography. Throughout, we illustrate cases where these constraints might be especially important in native populations faced with biological invasions. Our goal was to highlight additional complexities empiricists should consider when studying adaptation to biological invasions and to begin to identify conditions when adaptation may fail to be an effective response to invasion.

  11. Preliminary tsunami hazard assessment in British Columbia, Canada

    NASA Astrophysics Data System (ADS)

    Insua, T. L.; Grilli, A. R.; Grilli, S. T.; Shelby, M. R.; Wang, K.; Gao, D.; Cherniawsky, J. Y.; Harris, J. C.; Heesemann, M.; McLean, S.; Moran, K.

    2015-12-01

    Ocean Networks Canada (ONC), a not-for-profit initiative by the University of Victoria that operates several cabled ocean observatories, is developing a new generation of ocean observing systems (referred to as Smart Ocean Systems™), involving advanced undersea observation technologies, data networks and analytics. The ONC Tsunami project is a Smart Ocean Systems™ project that addresses the need for a near-field tsunami detection system for the coastal areas of British Columbia. Recent studies indicate that there is a 40-80% probability over the next 50 for a significant tsunami impacting the British Columbia (BC) coast with runups higher than 1.5 m. The NEPTUNE cabled ocean observatory, operated by ONC off of the west coast of British Columbia, could be used to detect near-field tsunami events with existing instrumentation, including seismometers and bottom pressure recorders. As part of this project, new tsunami simulations are underway for the BC coast. Tsunami propagation is being simulated with the FUNWAVE-TVD model, for a suite of new source models representing Cascadia megathrust rupture scenarios. Simulations are performed by one-way coupling in a series of nested model grids (from the source to the BC coast), whose bathymetry was developed based on digital elevation maps (DEMs) of the area, to estimate both tsunami arrival time and coastal runup/inundation for different locations. Besides inundation, maps of additional parameters such as maximum current are being developed, that will aid in tsunami hazard assessment and risk mitigation, as well as developing evacuation plans. We will present initial results of this work for the Port Alberni inlet, in particular Ucluelet, based on new source models developed using the best available data. We will also present a model validation using measurements of the 2011 transpacific Tohoku-oki tsunami recorded in coastal BC by several instruments from various US and Canadian agencies.

  12. Fail-safe designs for large capacity battery systems

    DOEpatents

    Kim, Gi-Heon; Smith, Kandler; Ireland, John; Pesaran, Ahmad A.; Neubauer, Jeremy

    2016-05-17

    Fail-safe systems and design methodologies for large capacity battery systems are disclosed. The disclosed systems and methodologies serve to locate a faulty cell in a large capacity battery, such as a cell having an internal short circuit, determine whether the fault is evolving, and electrically isolate the faulty cell from the rest of the battery, preventing further electrical energy from feeding into the fault.

  13. Paying for innovation. Failed strategies add to hospitals' reimbursement losses.

    PubMed

    Pallarito, K

    Hospitals across the country are struggling to balance revenue shortfalls and cost increases as the lid on government and private-payer payments closes tighter. They're also grappling with losses on failed physician and HMO investments, the expense of new medical technologies and larger-than-planned costs related to "millennium bug" cures. This is the second part of a two-part series on financial turmoil in healthcare.

  14. Reorganized PKA-AKAP associations in the failing human heart.

    PubMed

    Aye, Thin-Thin; Soni, Siddarth; van Veen, Toon A B; van der Heyden, Marcel A G; Cappadona, Salvatore; Varro, Andras; de Weger, Roel A; de Jonge, Nicolaas; Vos, Marc A; Heck, Albert J R; Scholten, Arjen

    2012-02-01

    Here we reveal that the characterization of large-scale re-arrangements of signaling scaffolds induced by heart failure can serve as a novel concept to identify more specific therapeutic targets. In the mammalian heart, the cAMP pathway, with the cAMP-dependent protein kinase (PKA) in a central role, acts directly downstream of adrenergic receptors to mediate cardiac contractility and rhythm. Heart failure, characterized by severe alterations in adrenergic stimulation is, amongst other interventions, often treated with β-blockers. Contrasting results, however, have shown both beneficial and detrimental effects of decreased cAMP levels in failing hearts. We hypothesize that the origin of this behavior lies in the complex spatiotemporal organization of the regulatory subunit of PKA (PKA-R), which associates tightly with various A-kinase anchoring proteins (AKAPs) to specifically localize PKA's activity. Using chemical proteomics directly applied to human patient and control heart tissue we demonstrate that the association profile of PKA-R with several AKAPs is severely altered in the failing heart, for instance effecting the interaction between PKA and the novel AKAP SPHKAP was 6-fold upregulated upon failing heart conditions. Also a significant increase in captured cGMP-dependent protein kinase (PKG) and phosphodiesterase 2 (PDE2) was observed. The observed altered profiles can already explain many aspects of the aberrant cAMP-response in the failing human heart, validating that this dataset may provide a resource for several novel, more specific, treatment options. This article is part of a Special Issue entitled "Local Signaling in Myocytes".

  15. Failing underperforming students: the role of grading in practice assessment.

    PubMed

    Heaslip, Vanessa; Scammell, Janet M E

    2012-03-01

    Nursing is essentially a practice discipline, informed by a theoretical base. It is crucial that students have a rigorous preparation in both theoretical and practical elements during their pre-registration programme. The aim of educationalists is to produce students fit for purpose and practice, but concerns have been raised internationally regarding students competence at the point of registration. There is evidence that some practice based assessors experience difficulties in failing incompetent students. Assessment of practice is often judged on a pass/fail rather than a graded basis in a number of health professional programmes. It could be argued that pass or fail provides limited feedback to students concerning exactly how well or poorly they have performed. This paper will explore these issues through focusing on selected findings from a service evaluation of a practice assessment tool incorporating grading of practice of pre-registration nursing students from one university in the United Kingdom (UK). Using convenience sampling, a questionnaire survey was completed by 107 adult, mental health and child health nursing students (51% response) and 112 mentors (practice-based assessors) (86% response) from all nursing fields. Amongst other issues, the evaluation identified that whilst mentors valued the opportunity to grade practice and perceived that the tool enabled them to be more discerning in the allocation of pass grades, some lacked confidence in failing students. The findings are discussed in the context of the wider debate around clinical competence in new nurse registrants and it is concluded that whilst assessing 'borderline' students will always be a testing experience, grading systems may help the assessor to be more discriminatory.

  16. Earthquake hazard mapping for lifeline engineering Coquitlam, British Columbia

    SciTech Connect

    Gohl, W.B.; Hawson, H.H.; Dou, H.; Nyberg, N.; Lee, R.; Wong, H.

    1995-12-31

    A series of maps plotted at a 1:15,000 scale were prepared to illustrate geotechnical aspects of seismic hazard for the 475 year return period earthquake event within the City of Coquitlam located in the Vancouver Lower Mainland of British Columbia. The maps were prepared to facilitate evaluation of lifeline damage potential within the City of Coquitlam (e.g. roads, sewers, water supply lines, oil/gas pipelines, power lines, compressor/pumping stations, water reservoirs, bridges, and rail lines) and to assist in evaluation of the impact of seismic ground shaking on new infrastructure.

  17. The Americanization of the British National Health Service.

    PubMed

    Mechanic, D

    1995-01-01

    The core reform of the British National Health Service (NHS) was the establishment of a quasi market with a split between purchasers and providers. Health authorities and general practitioner (GP) fundholders were to be discriminating purchasers seeking more efficient and responsive services. This market orientation was embedded in a larger context of managerial, allocational, public health, and primary care changes. This paper reviews the background and dynamics of these modifications and offers an early assessment. There is evidence that the reforms have unleashed much energy, activity, and thoughtfulness about future health care, but it remains unclear whether the gains justify the increased administrative and other transaction costs and potential threats to equal access.

  18. "Signs of the times": Medicine and nationhood in British India.

    PubMed

    Chakrabarti, Pratik

    2009-01-01

    Medical practice and research in colonial India historically had been an imperial preserve, dominated by the elite members of the Indian Medical Service. This was contested from the 1900s on by the emerging Indian nationalism. This essay studies debates about the establishment of a medical research institution and how actors imposed the political identities of nationalism on British colonial practices of medical science. At the same time, Indian nationalism was also drawing from other emerging ideas around health and social welfare. The Indian nationalists and doctors sought to build the identities of the new nation and its medicine around their own ideas of its geography, people, and welfare.

  19. Allelic melanism in American and British peppered moths.

    PubMed

    Grant, B S

    2004-01-01

    Parallel evolutionary changes in the incidence of melanism are well documented in widely geographically separated subspecies of the peppered moth (Biston betularia). The British melanic phenotype (f. carbonaria) and the American melanic phenotype (f. swettaria) are indistinguishable in appearance, and previous genetic analysis has established that both are inherited as autosomal dominants. This report demonstrates through hybridizations of the subspecies and Mendelian testcrosses of melanic progeny that carbonaria and swettaria are phenotypes produced by alleles (isoalleles) at a single locus. The possibility of close linkage at two loci remains, but the simpler one-locus model cannot be rejected in the absence of contrary evidence.

  20. “I'm Managing My Diabetes between Two Worlds”: Beliefs and Experiences of Diabetes Management in British South Asians on Holiday in the East—A Qualitative Study

    PubMed Central

    Patel, Neesha R.; Kennedy, Anne; Blickem, Christian; Reeves, David; Chew-Graham, Carolyn

    2016-01-01

    Background. Diabetes is disproportionately high among British South Asians compared to the general UK population. Whilst the migrant British South Asians group has received most attention on research related to diabetes management, little consideration has been given to impact of travel back to the East. This study aimed to explore the role of social networks and beliefs about diabetes in British South Asians, to better understand their management behaviours whilst holidaying in the East. Methods. Semistructured interviews were conducted in Greater Manchester. Forty-four participants were recruited using random and purposive sampling techniques. Interviews were analysed thematically using a constant comparison approach. Results. Migrant British South Asians expressed a strong preference to be in a hot climate; they felt they had a healthier lifestyle in the East and often altered or abandoned their diabetes medication. Information acquisition on diabetes and availability of social networks in the East was valued. Conclusion. Social networks in the East are a valued source of information and support for diabetes. The lack of adherence to medication whilst abroad suggests that some migrant British South Asians have a poor understanding of diabetes. Future research needs to explore whether patients are seeking professional advice on diabetes management prior to their extended holiday. PMID:26697499

  1. Rescue of failed filtering blebs with ab interno trephination.

    PubMed

    Shihadeh, Wisam A; Ritch, Robert; Liebmann, Jeffrey M

    2006-06-01

    We evaluated the effectiveness of ab interno automated trephination as a technique for rescuing failed mature filtering blebs. A retrospective chart review of 40 failed blebs of 38 patients who had a posttrephination follow-up period of at least 3 months was done. With success defined as intraocular pressure (IOP) <21 mm Hg and at least a 20% reduction from baseline on the same or fewer number of pretrephination medications, 30/40 eyes (75%) fit these criteria over the entire course of follow-up. Among all 40 eyes, there was a significant reduction of IOP from pretrephination to 3 months (P<.001). The percentage of patients requiring 2 or more medications declined from 90% pretrephination to 21% at 3 months (P<.0001), and was stable thereafter. Some patients were able to eliminate all medications. Patients who did not meet the criteria of success regained successful IOP control with other modalities of management. Complications were few. We believe that ab interno trephination is an excellent option for rescuing selected failed filtering blebs.

  2. Population fluctuation in phytophagous insects

    SciTech Connect

    Redfearn, A.; Pimm, S.L. )

    1994-06-01

    We examined how community interactions affect year-to-year population variability in three groups of phytophagous insects: British aphids and moths, and Canadian moths. We first examined how the number of host plant species on which a given phytophagous insect species feeds affects its population variability. Specialist insect species showed a weak tendency to be more variable than generalist species. We then examined how the number of species of parasitoids from which a given phytophagous insects species suffers affects its population variability. Species that are host to few parasitoid species showed a weak tendency to be more variable than species with many parsitoid species. These relationships also depend on other aspects of the life histories of the phytophagous insect species.

  3. Long-term trends in the longevity of scientific elites: evidence from the British and the Russian academies of science.

    PubMed

    Andreev, Evgeny M; Jdanov, Dmitri; Shkolnikov, Vladimir M; Leon, David A

    2011-11-01

    National science academies represent intellectual elites and vanguard groups in the achievement of longevity. We estimated life expectancy (LE) at age 50 of members of the British Royal Society (RS) for the years 1670-2007 and of members of the Russian Academy of Sciences (RAS) for the years 1750-2006. The longevity of academicians was higher than that of their corresponding national populations, with the gap widening from the 1950s. Since the 1980s, LE in the RS has been higher than the maximum LE among all high-income countries. In each period, LE in the RS was greater than in the RAS, although since the 1950s it has risen in parallel in the two academies. This steep increase shared by academicians in Britain and Russia suggests that general populations have the potential for a substantial increase in survival to high ages.

  4. Does amblyopia affect educational, health, and social outcomes? Findings from 1958 British birth cohort

    PubMed Central

    Rahi, J S; Cumberland, P M; Peckham, C S

    2006-01-01

    Objective To determine any association of amblyopia with diverse educational, health, and social outcomes in order to inform current debate about population screening for this condition. Design, setting, and participants Comparison of 8432 people with normal vision in each eye with 429 (4.8%) people with amblyopia (childhood unilateral reduced acuity when tested with correction and unaccounted for by eye disease) from the 1958 British birth cohort, with respect to subsequent health and social functioning. Results No functionally or clinically significant differences existed between people with and without amblyopia in educational outcomes, behavioural difficulties or social maladjustment, participation in social activities, unintended injuries (school, workplace, or road traffic accidents as driver), general or mental health and mortality, paid employment, or occupation based social class trajectories. Conclusions It may be difficult to distinguish, at population level, between the lives of people with amblyopia and those without, in terms of several important outcomes. A pressing need exists for further concerted research on what it means to have amblyopia and, specifically, how this varies with severity and how it changes with treatment, so that screening programmes can best serve those who have the most to gain from early identification. PMID:16520328

  5. Prevalence of masturbation and associated factors in a British national probability survey.

    PubMed

    Gerressu, Makeda; Mercer, Catherine H; Graham, Cynthia A; Wellings, Kaye; Johnson, Anne M

    2008-04-01

    A stratified probability sample survey of the British general population, aged 16 to 44 years, was conducted from 1999 to 2001 (N = 11,161) using face-to-face interviewing and computer-assisted self-interviewing. We used these data to estimate the population prevalence of masturbation, and to identify sociodemographic, sexual behavioral, and attitudinal factors associated with reporting this behavior. Seventy-three percent of men and 36.8% of women reported masturbating in the 4 weeks prior to interview (95% confidence interval 71.5%-74.4% and 35.4%-38.2%, respectively). A number of sociodemographic and behavioral factors were associated with reporting masturbation. Among both men and women, reporting masturbation increased with higher levels of education and social class and was more common among those reporting sexual function problems. For women, masturbation was more likely among those who reported more frequent vaginal sex in the last four weeks, a greater repertoire of sexual activity (such as reporting oral and anal sex), and more sexual partners in the last year. In contrast, the prevalence of masturbation was lower among men reporting more frequent vaginal sex. Both men and women reporting same-sex partner(s) were significantly more likely to report masturbation. Masturbation is a common sexual practice with significant variations in reporting between men and women.

  6. Blast furnace coal injection at Scunthorpe Works, British Steel plc

    SciTech Connect

    Matheau-Raven, D.

    1996-12-31

    Granulator coal injection has been practiced since 1982 at Scunthorpe Works, British Steel plc. The Works is world famous for its four Queens of Ironmaking, named Victoria, Anne, Bess and Mary. These four blast furnaces are capable of producing 4.1 million tonnes of hot metal per annum. The coal injection system was a joint development venture between British Steel and a local based company call Clyde Pneumatic Conveyors. After 14 years of operation and regulator use, Scunthorpe`s coal injection rates have risen to become among the highest in the world. Total coal injected stands at around 4 million tonnes and coal injection rates of greater than 200 kg/thm have been achieved. The furnace operation has remained smooth throughout and there have been no measurable detrimental effects upon the blast furnace performance. In fact quite the opposite with several benefits. This paper briefly describes the furnaces and the coal injection equipment. Operating results for a full twelve months are given and discussed as are aspects of the blast furnace operating practice enabling these injection rates to be achieved. In financial terms savings totaling around 14 million pounds sterling per annum have been realized through the use of blast furnace coal injection.

  7. The Role of Capital Productivity in British Airways' Financial Recovery

    NASA Technical Reports Server (NTRS)

    Morrell, Peter

    1999-01-01

    British Airways (BA) was privatised in 1987, but its financial recovery occurred a number of years earlier. This recovery was sustained throughout the early 1990s economic recession, a period when few major airlines were operating profitably. This paper examines the role of productivity developments at British Airways from the early 1980s through 1996. The emphasis is on capital productivity and investment, but changes in capital intensity and labour productivity are also evaluated. Various measures are considered for both capital and labour productivity: outputs are measured in available tonne-kms (ATKS) and revenue tonne-kms (RTKs), with the former preferred over the latter two measures, after adjustment for work performed by BA for others. Capital inputs are measured in equivalent lease costs adjusted to constant prices with a different treatment of flight and ground equipment or assets. Labour inputs are derived from total payroll costs deflated by a UK wage price index. The airline made considerable capital investments over the period and at the same time went through two major processes of labour restructuring. This resulted in a gradual increase in capital intensity, relative high labour productivity growth, but poor capital productivity performance. However, capital investment played an important role in the airline's sustained labour and total factor productivity over the whole period.

  8. The Role of Capital Productivity in British Airways' Financial Recovery

    NASA Technical Reports Server (NTRS)

    Morrell, Peter

    1999-01-01

    British Airways (BA) was privatized in 1987, but its financial recovery occurred a number of years earlier, This recovery was sustained throughout the early 1990s economic recession, a period when few major airlines were operating profitably. This paper examines the role of productivity developments at British Airways from the early 1980s through 1996. The emphasis is on capital productivity and investment, but changes in capital intensity and labour productivity are also evaluated. Various measures are considered for both capital and labour productivity: outputs are measured in available tonne-kms (ATKs) and revenue tonne-kms (RTKs), with the former preferred over the latter two measures, after adjustment for work performed by BA for others. Capital inputs are measured in equivalent lease costs adjusted to constant prices with a different treatment of flight and ground equipment or assets. Labour inputs are derived from total payroll costs deflated by a UK wage price index. The airline made considerable capital investments over the period and at the same time went through two major processes of labour restructuring. This resulted in a gradual increase in capital intensity, relative high labour productivity growth, but poor capital productivity performance, However, capital investment played an important role in the airline's sustained labour and total factor productivity over the whole period.

  9. Providers' perceptions of Aboriginal palliative care in British Columbia's rural interior.

    PubMed

    Castleden, Heather; Crooks, Valorie A; Hanlon, Neil; Schuurman, Nadine

    2010-09-01

    Aboriginal Canadians experience a disproportionate burden of ill-health and have endured a history of racism in accessing and using health care. Meanwhile, this population is rapidly growing, resulting in an urgent need to facilitate better quality of living and dying in many ways, including through enhancing (cultural) access to palliative care. In this article, we report the findings from a qualitative case study undertaken in rural British Columbia, Canada through exploring the perceptions of Aboriginal palliative care in a region identified as lacking in formal palliative care services and having only a limited Aboriginal population. Using interview data collected from 31 formal and informal palliative care providers (May-September 2008), we thematically explore not only the existing challenges and contradictions associated with the prioritisation and provision of Aboriginal palliative care in the region in terms of (in)visibility but also identify the elements necessary to enhance such care in the future. The implications for service providers in rural regions are such that consideration of the presence of small, and not always 'visible', populations is necessary; while rural care providers are known for their resilience and resourcefulness, increased opportunities for meaningful two-way knowledge exchange with peers and consultation with experts cannot be overlooked. Doing so will serve to enhance culturally accessible palliative care in the region in general and for Aboriginal peoples specifically. This analysis thus contributes to a substantial gap in the palliative care literature concerning service providers' perceptions surrounding Aboriginal palliative care as well as Aboriginal peoples' experiences with receiving such care. Given the growing Aboriginal population and continued health inequities, this study serves to not only increase awareness but also create better living and dying conditions in small but incremental ways.

  10. 40 CFR 205.171-8 - Passing or failing under SEA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Passing or failing under SEA. 205.171... Passing or failing under SEA. (a) A failing exhaust system is one which, when installed on any motorcycle... standard in § 205.166. (b) The number of failing vehicles in a sample determines whether the sample...

  11. 40 CFR 1068.420 - How do I know when my engine family fails an SEA?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... fails an SEA? 1068.420 Section 1068.420 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Auditing § 1068.420 How do I know when my engine family fails an SEA? (a) A failed engine or piece of... pollutants or a fail decision for one pollutant. (c) You reach a pass decision for the SEA requirements...

  12. Benjamin Franklin's Pictorial Representations of the British Colonies in America: A Study in Rhetorical Iconology.

    ERIC Educational Resources Information Center

    Olson, Lester C.

    1987-01-01

    Investigates the underlying reasons for the fundamental shift in Benjamin Franklin's portrayals of the British colonies in America. Explores the hypothesis that "Magna Britannia" was both a deliberative work directed toward the British Parliament and an apologetic work directed toward conservatives in the colonial public. Also discusses…

  13. How British-Chinese Parents Support Their Children: A View from the Regions

    ERIC Educational Resources Information Center

    Gates, Peter; Guo, Xumei

    2014-01-01

    Although the high level of achievement experienced by British-Chinese pupils in schools is well documented, the Chinese community in the UK is a relatively under-researched ethnic group. There is only patchy information on ways in which British-Chinese parents and children engage with education. It is often presumed the success of Chinese pupils…

  14. Associate Degrees Awarded in British Columbia, 1993-94 to 2005-06

    ERIC Educational Resources Information Center

    Karlinski, Jean

    2007-01-01

    The Associate Degree is a two year academic credential available with an Arts or Science focus. The British Columbia Council on Admissions and Transfer (BCCAT) initiated development of this provincial credential at the request of British Columbia's (BC's) public post-secondary institutions. In March 2003, BCCAT prepared a report detailing the…

  15. Transfer in British Columbia: What Does the Research Tell Us? Research Results

    ERIC Educational Resources Information Center

    Cowin, Bob

    2004-01-01

    Findings from the British Columbia Council on Admissions and Transfer (BCCAT) sponsored research describing the British Columbia (BC) transfer system over the past decade are summarized. The overall assessment is that the transfer system has performed well: many students have transferred, they have done so with relative ease, and they have…

  16. 75 FR 59170 - Airworthiness Directives; British Aerospace Regional Aircraft Models Jetstream Series 3101 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; British Aerospace... available in the AD docket shortly after receipt. FOR FURTHER INFORMATION CONTACT: Taylor Martin, Aerospace... British Aerospace Jetstream Series 3100 & 3200 Service Bulletin 05-JA090143, dated April 30, 2009;...

  17. Perceptions of Being International: Differences between British Adolescents Living Abroad and Those at Home

    ERIC Educational Resources Information Center

    Lam, Hon; Selmer, Jan

    2004-01-01

    British adolescents living in Hong Kong and British adolescents living in the United Kingdom formed the two samples of adolescents who completed Hayden, Rancic and Thompson's (2000) 32-item instrument. Instead of following the original authors' approach to the analysis of the instrument, a more comprehensive technique was adopted. The data were…

  18. Green Consciousness or Dollar Diplomacy? The British Response to the Threat of Ozone Depletion.

    ERIC Educational Resources Information Center

    Maxwell, James H.; Weiner, Sanford L.

    1993-01-01

    Discusses the British role in the regulation of believed ozone-depleting substances such as chlorofluorocarbons. Recounts the history of the British policies during the emergence of the issue from 1974-80; a period of tactical resistance from 1980-87; and a change in policy from 1987-90. (66 references) (MDH)

  19. Using Web-Based Technologies and Tools in Future Choreographers' Training: British Experience

    ERIC Educational Resources Information Center

    Bidyuk, Dmytro

    2016-01-01

    In the paper the problem of using effective web-based technologies and tools in teaching choreography in British higher education institutions has been discussed. Researches on the usage of web-based technologies and tools for practical dance courses in choreographers' professional training at British higher education institutions by such British…

  20. British Chemists Abroad, 1887-1971: The Dynamics of Chemists' Careers

    ERIC Educational Resources Information Center

    Roberts, Gerrylynn K.; Simmons, Anna E.

    2009-01-01

    This paper investigates the extent of overseas migration by British chemists over the period 1887-1971. Notwithstanding the "brain drain" alarms of the 1960s, overseas employment was characteristic of some 19% of British chemists' careers throughout our period, though its nature changed considerably. Our study examines the overseas…

  1. Consensus management in the British National Health Service: implications for the United States?

    PubMed

    Schulz, R; Harrison, S

    1984-01-01

    Most operational services within the reorganized British National Health Service are managed by local teams: medical specialist, general practitioner, nurse, administrator, and finance officer. Decision by consensus has worked well to integrate services in a complex and fiscally constrained system. As larger and more formal systems of health care emerge in the United States, the British experience may be relevant.

  2. A Common Language: British and American English, Conversations Between Albert H. Marckwardt and Randolph Quirk.

    ERIC Educational Resources Information Center

    Marckwardt, Albert H.; Quirk, Randolph

    This transcription of radio conversations on the English language between Albert H. Marckwardt and Randolph Quirk, jointly produced by The British Broadcasting Corporation and The Voice of America, indicates that American and British English have never been so different as people have imagined and that the dominant tendency has been toward…

  3. Linguistically-Relevant Diachronic Study of Cultural Values in Early British Advertising Discourse

    ERIC Educational Resources Information Center

    Kochetova, Larisa A.

    2016-01-01

    Drawing on linguistic data retrieved from early advertisements published in British newspapers between 1788 and 1900, the study seeks to map out a set of values and account for linguistic means used to codify them in the diachronic perspective. For the purposes of the study, the corpus of advertisements from random issues of British newspapers…

  4. The "Heart" of the European "Body Politic". British and German Perspectives on Europe's Central "Organ"

    ERIC Educational Resources Information Center

    Musolff, Andreas

    2004-01-01

    On the basis of a corpus of British and German press coverage of European Union (EU) politics over the 1990s, the paper analyses uses of the geopolitical HEART metaphor. Over the course of the 1990s, successive British governments promised to work "at" the "heart of Europe". However, no one ever claimed that Britain was…

  5. Britishness, Belonging and the Ideology of Conflict: Lessons from the "Polis"

    ERIC Educational Resources Information Center

    Edyvane, Derek

    2011-01-01

    A central aspiration of the "Britishness" agenda in UK politics is to promote community through the teaching of British values in schools. The agenda's justification depends in part on the suppositions that harmony arising from agreement on certain values is a necessary condition of social health and that conflict arising from pluralism…

  6. Beneficial effects of SR33805 in failing myocardium

    PubMed Central

    Ait Mou, Younss; Toth, Attila; Cassan, Cécile; Czuriga, Daniel; de Tombe, Pieter P.; Papp, Zoltan; Lacampagne, Alain; Cazorla, Olivier

    2011-01-01

    Aims SR33805, a potent Ca2+ channel blocker, increases cardiac myofilament Ca2+ sensitivity in healthy rat cardiomyocytes. Therefore, the aim of the present study was to evaluate the effects of SR33805 on contractile properties in ischaemic failing hearts after myocardial infarction (MI) in vivo and in vitro at the cellular level. Methods and results The effect of SR33805 (10 µM) was tested on the excitation–contraction coupling of cardiomyocytes isolated from rat with end-stage heart failure. Cell shortening and Ca2+ transients were measured in intact cardiomyocytes, while contractile properties were determined in Triton X-100 permeabilized myocytes. Acute treatment with SR33805 restored the MI-altered cell shortening without affecting the Ca2+ transient amplitude, suggesting an increase of myofilament Ca2+ sensitivity in MI myocytes. Indeed, a SR33805-induced sensitization of myofilament activation was found to be associated with a slight increase in myosin light chain-2 phosphorylation and a more significant decrease on troponin I (TnI) phosphorylation. Decreased TnI phosphorylation was related to inhibition of protein kinase A activity by SR33805. Finally, administration of a single intra-peritoneal bolus of SR33805 (20 mg/kg) improved end-systolic strain and fractional shortening of MI hearts. Conclusion The present study indicates that treatment with SR33805 improved contractility of ischaemic failing hearts after MI in the rat by selectively modulating the phosphorylation status of sarcomeric regulatory proteins, which then sensitized the myofilaments to Ca2+. Our results gave a proof of concept that manipulation of the Ca2+ sensitivity of sarcomeric regulatory proteins can be used to improve contractility of a failing heart. PMID:21467075

  7. Failed magmatic eruptions: Late-stage cessation of magma ascent

    USGS Publications Warehouse

    Moran, S.C.; Newhall, C.; Roman, D.C.

    2011-01-01

    When a volcano becomes restless, a primary question is whether the unrest will lead to an eruption. Here we recognize four possible outcomes of a magmatic intrusion: "deep intrusion", "shallow intrusion", "sluggish/viscous magmatic eruption", and "rapid, often explosive magmatic eruption". We define "failed eruptions" as instances in which magma reaches but does not pass the "shallow intrusion" stage, i. e., when magma gets close to, but does not reach, the surface. Competing factors act to promote or hinder the eventual eruption of a magma intrusion. Fresh intrusion from depth, high magma gas content, rapid ascent rates that leave little time for enroute degassing, opening of pathways, and sudden decompression near the surface all act to promote eruption, whereas decreased magma supply from depth, slow ascent, significant enroute degassing and associated increases in viscosity, and impingement on structural barriers all act to hinder eruption. All of these factors interact in complex ways with variable results, but often cause magma to stall at some depth before reaching the surface. Although certain precursory phenomena, such as rapidly escalating seismic swarms or rates of degassing or deformation, are good indicators that an eruption is likely, such phenomena have also been observed in association with intrusions that have ultimately failed to erupt. A perpetual difficulty with quantifying the probability of eruption is a lack of data, particularly on instances of failed eruptions. This difficulty is being addressed in part through the WOVOdat database. Papers in this volume will be an additional resource for scientists grappling with the issue of whether or not an episode of unrest will lead to a magmatic eruption.

  8. US bituminous coal test program in the British Gas/Lurgi (BGL) gasifier. Final report

    SciTech Connect

    de Souza, M.D.; Tart, K.R.; Eales, D.F.; Turna, O.

    1991-12-01

    The BGL moving-bed, slagging-gasification process is an extension of the commercially proven Lurgi dry-ash, moving-bed gasification process. British Gas and Lurgi have demonstrated the process over an 11-year period at the 350 and 500 t/d scale at British Gas` Westfield Development Center, Scotland, with a wide variety of US and British coals. British Gas also installed a gas purification and HICOM methanation plant at Westfield to treat approximately 190,000 sft{sup 3}/h of purified syngas. Objectives are: To demonstrate the suitability of US bituminous coals as feed-stocks in the BGL gasification process; to provide performance data for use in designing commercial-scale BGL-based gasification-combined-cycle (GCC) power plants; and to evaluate the performance of the British Gas HICOM process for methanation of US coal-derived syngas.

  9. US bituminous coal test program in the British Gas/Lurgi (BGL) gasifier

    SciTech Connect

    de Souza, M.D.; Tart, K.R.; Eales, D.F. ); Turna, O. )

    1991-12-01

    The BGL moving-bed, slagging-gasification process is an extension of the commercially proven Lurgi dry-ash, moving-bed gasification process. British Gas and Lurgi have demonstrated the process over an 11-year period at the 350 and 500 t/d scale at British Gas' Westfield Development Center, Scotland, with a wide variety of US and British coals. British Gas also installed a gas purification and HICOM methanation plant at Westfield to treat approximately 190,000 sft{sup 3}/h of purified syngas. Objectives are: To demonstrate the suitability of US bituminous coals as feed-stocks in the BGL gasification process; to provide performance data for use in designing commercial-scale BGL-based gasification-combined-cycle (GCC) power plants; and to evaluate the performance of the British Gas HICOM process for methanation of US coal-derived syngas.

  10. Fired worker fails to meet ADA's 'regarded as' test.

    PubMed

    1998-08-07

    [Name removed], a waiter at a Long Island [name removed], claimed that he was fired based on the misconception that because he was gay, he was HIV-positive. [Name removed] sued under the Federal Rehabilitation Act and the Americans with Disabilities Act, because there is not a law in NY that protects people from discrimination based on sexual orientation. The court rejected his claim by saying that he failed to provide a factual basis for his allegations. The employers stated that they fired [name removed] for using profanity toward a coworker, while on the job.

  11. Sjögren Syndrome: Why Do Clinical Trials Fail?

    PubMed

    Fox, Robert I; Fox, Carla M

    2016-08-01

    Sjögren syndrome (SS) comprises glandular and extraglandular manifestations. Double-blind prospective trials of traditional disease-modifying antirheumatic drugs and biologics have failed because they have not improved benign symptoms, the major cause of lowered quality of life. Rituximab has proven effective in SS patients with associated mixed cryoglobulinemia, parotid gland swelling, lymphocytic interstitial pneumonitis, thrombocytopenia, and other manifestations. There were few of these SS patients in the trials required for FDA approval. Most patients had benign symptoms and did not show benefit, leading to failure of the study. This article examines the reasons for these failures and proposes future directions.

  12. Fail-safe storage rack for irradiated fuel rod assemblies

    DOEpatents

    Lewis, Donald R.

    1993-01-01

    A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  13. Fail-safe storage rack for irradiated fuel rod assemblies

    DOEpatents

    Lewis, D.R.

    1993-03-23

    A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  14. Surgical management of vestibular schwannomas after failed radiation treatment.

    PubMed

    Nonaka, Yoichi; Fukushima, Takanori; Watanabe, Kentaro; Friedman, Allan H; Cunningham, Calhoun D; Zomorodi, Ali R

    2016-04-01

    Increasing numbers of patients with vestibular schwannoma (VS) have been treated with focused-beam stereotactic radiation treatment (SRT) including Gamma knife, CyberKnife, X-knife, Novalis, or proton beam therapy. The purpose of this study was to document the incidence of tumor regrowth or symptoms that worsened or first developed following SRT and to discuss surgical strategies for patients who have failed SRT for VS. A consecutive series of 39 patients with SRT failed VS were surgically treated. Clinical symptoms, tumor regrowth at follow-up, intraoperative findings, and surgical outcome were evaluated. There were 15 males and 24 females with a mean age of 51.8 years. Thirty-six patients (92.3%) demonstrated steady tumor growth after SRT. Two (5.1%) patients with slight increase of the mass underwent surgical resection because of development of unbearable facial pain. Symptoms that worsened or newly developed following SRT in this series were deafness (41%), dizziness (35.9%), facial numbness (25.6%), tinnitus (20.5%), facial nerve palsy (7.7%), and facial pain (7.7%). Intraoperative findings demonstrated fibrous changes of the tumor mass, cyst formation, and brownish-yellow or purple discoloration of the tumor capsule. Severe adhesions between the tumor capsule and cranial nerves, vessels, and the brainstem were observed in 69.2%. Additionally, the facial nerve was more fragile and irritable in all cases. Gross total resection (GTR) was achieved in 33.3% of patients, near-total resection (NTR) in 35.9%, and subtotal resection (STR) in 30.8% of patients. New facial nerve palsy was seen in seven patients (19.4%) postoperatively. Our findings suggest that patients with VS who fail SRT with either tumor progression or worsening of clinical symptoms will have an increased rate of adhesions to the neurovascular structures and may have radiation-influenced neuromalacia. Salvage surgery of radiation-failed tumors is more difficult and will have a higher risk of

  15. Improved Quick Disconnect (QD) Interface Through Fail Safe Parts Identification

    NASA Technical Reports Server (NTRS)

    Blanch-Payne, Evelyn

    2001-01-01

    An extensive review of existing Quick Disconnects (QDs) mating and demating operations was performed to determine which shuttle part interface identifications and procedures contribute to human factor errors. The research methods used consisted of interviews with engineers and technicians, examination of incident reports, critiques of video and audio tapes of QD operations, and attendance of a Hyper QD operational course. The data strongly suggests that there are inherit human factor errors involved in QD operations. To promote fail-safe operations, QD interface problem areas and recommendations were outlined and reviewed. It is suggested that dialogue, investigations and recommendations continue.

  16. Analysis of failed ramps during the RHIC FY09 run

    SciTech Connect

    Minty, M.

    2014-08-15

    The Relativistic Heavy Ion Collider (RHIC) is a versatile accelerator that supports operation with polarized protons of up to 250 GeV and ions with up to 100 GeV/nucleon. During any running period, various operating scenarios with different particle species, beam energies or accelerator optics are commissioned. In this report the beam commissioning periods for establishing full energy beams (ramp development periods) from the FY09 run are summarized and, for the purpose of motivating further developments, we analyze the reasons for all failed ramps.

  17. Fail-safe storage rack for fuel rod assemblies

    SciTech Connect

    Lewis, D.R.

    1991-12-31

    This report discusses a fail-safe storage rack which is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  18. Re-evaluation of the metabolism of carbocisteine in a British white population.

    PubMed

    Gregory, W L; James, O F; Turner, I; Meese, C O; Idle, J R

    1993-10-01

    It has been claimed that the amino acid derivative carbocisteine is predominantly metabolized by sulfoxidation and that this pathway exhibits a genetic polymorphism. Moreover, those subjects with a 'poor metabolizer' phenotype have been thought to have a genetic predisposition to developing certain diseases. We have confirmed the observations of others that this marker drug does not undergo significant S-oxidation. Furthermore, a novel urinary metabolite, S-(carboxymethylthio)-L-cysteine (CMTC) has recently been identified. To determine if a genetic polymorphism for this biotransformation pathway exists, metabolic ratios (% urinary excretion carbocisteine/% urinary excretion CMTC) for 120 healthy volunteers were assessed using high-performance thin-layer chromatography. Urinary excretion of the parent drug ranged from 6% of the dose administered to 56% (mean +/- SD, 23.4 +/- 0.8%). No cysteinyl sulfoxide metabolites were identified in the urine samples. The amount excreted as CMTC exhibited a 12-fold variation but only accounted for mean of 4.4% (1-12%) of the dose given. Two individuals initially had high metabolic ratios (> 30), however, on rechallenge both their MRs were less than 5. Therefore, carbocisteine is not an appropriate probe drug for sulfoxidation. The formation of the novel metabolite CMTC appears to exhibit polymorphism, although the considerable intra-subject variation for its formation does not allow assignment of a phenotype.

  19. Population screening for diabetes mellitus. Professional Advisory Committee of the British Diabetic Association.

    PubMed

    Paterson, K R

    1993-10-01

    The role and value of screening for diabetes mellitus is still unclear. If asymptomatic subjects are to be screened, then a fasting plasma glucose > 6.6 mmol l-1 or a venous plasma glucose 2 h after a 75 g oral glucose load > 8.0 mmol l-1 or the presence of any glucose in a urine sample passed 2 h after a main meal should be regarded as a positive result. A fasting plasma glucose in the range 5.5-6.6 mmol l-1 is an equivocal result which should lead to retesting in 6-12 months if there is any risk factor for diabetes (obesity, family history of diabetes, Asian/African racial origin). Other screening tests or combinations of tests are not recommended. Screening should be restricted to subjects between 40 and 75 years and should be undertaken only every 5 years (3 years if a risk factor for diabetes is present), ideally in parallel with other health screening test; subjects with a positive result should have further investigations as necessary to reach a diagnosis in line with WHO criteria.

  20. 77 FR 45869 - Endangered and Threatened Wildlife and Plants; Listing the British Columbia Distinct Population...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... habitat. Logging of old-growth forest, where the bird nests and forages, was the primary threat identified... expressed concern for long-term viability of the bird under the existing management plan for the Tongass... perches. They take a variety of medium-sized birds and mammals, depending largely on local...