Semantic Expression and Execution of B2B Contracts on Multimedia Content

NASA Astrophysics Data System (ADS)

Rodríguez-Doncel, Víctor; Delgado, Jaime

Business to business commerce of audiovisual material can be governed by electronic contracts, in the same way as digital licenses govern business to consumer transactions. The digital licenses for end users have been expressed either in proprietary formats or in standard Rights Expression Languages and they can be seen as the electronic replacement of distribution contracts and end user licenses. However, these languages fail to replace the rest of the contracts agreed along the complete Intellectual Property value chain. To represent their corresponding electronic counterpart licenses, a schema based on the standard eContracts and the Media Value Chain Ontology is presented here. It has been conceived to deal with a broader set of parties, to handle typical clauses found in the audiovisual market contracts, and to govern every transaction performed on IP objects.

Improving Access to Precipitation Data for GIS Users: Designing for Ease of Use

NASA Technical Reports Server (NTRS)

Stocker, Erich F.; Kelley, Owen A.

2007-01-01

The Global Precipitation Measurement Mission (GPM) is a NASA/JAXA led international mission to configure a constellation of space-based radiometers to monitor precipitation over the globe. The GPM goal of making global 3-hour precipitation products available in near real-time will make such global products more useful to a broader community of modelers and Geographic Information Systems (GIS) users than is currently the case with remote sensed precipitation products. Based on the existing interest to make Tropical Rainfall Measuring Mission (TRMM) data available to a growing community of GIS users as well as what will certainly be an expanded community during the GPM era, it is clear that data systems must make a greater effort to provide data in formats easily used by GIS. We describe precipitation GIS products being developed for TRMM data. These products will serve as prototypes for production efforts during the GPM era. We describe efforts to convert TRMM precipitation data to GeoTIFF, Shapefile, and ASCII grid. Clearly, our goal is to format GPM data so that it can be easily used within GIS applications. We desire feedback on these efforts and any additions or direction changes that should be undertaken by the data system.

High-resolution 3D imaging of polymerized photonic crystals by lab-based x-ray nanotomography with 50-nm resolution

NASA Astrophysics Data System (ADS)

Yin, Leilei; Chen, Ying-Chieh; Gelb, Jeff; Stevenson, Darren M.; Braun, Paul A.

2010-09-01

High resolution x-ray computed tomography is a powerful non-destructive 3-D imaging method. It can offer superior resolution on objects that are opaque or low contrast for optical microscopy. Synchrotron based x-ray computed tomography systems have been available for scientific research, but remain difficult to access for broader users. This work introduces a lab-based high-resolution x-ray nanotomography system with 50nm resolution in absorption and Zernike phase contrast modes. Using this system, we have demonstrated high quality 3-D images of polymerized photonic crystals which have been analyzed for band gap structures. The isotropic volumetric data shows excellent consistency with other characterization results.

Electronic health record "super-users" and "under-users" in ambulatory care practices.

PubMed

Rumball-Smith, Juliet; Shekelle, Paul; Damberg, Cheryl L

2018-01-01

This study explored variation in the extent of use of electronic health record (EHR)-based health information technology (IT) functionalities across US ambulatory care practices. Use of health IT functionalities in ambulatory care is important for delivering high-quality care, including that provided in coordination with multiple practitioners. We used data from the 2014 Healthcare Information and Management Systems Society Analytics survey. The responses of 30,123 ambulatory practices with an operational EHR were analyzed to examine the extent of use of EHR-based health IT functionalities for each practice. We created a novel framework for classifying ambulatory care practices employing 7 domains of health IT functionality. Drawing from the survey responses, we created a composite "use" variable indicating the extent of health IT functionality use across these domains. "Super-user" practices were defined as having near-full employment of the 7 domains of health IT functionalities and "under-users" as those with minimal or no use of health IT functionalities. We used multivariable logistic regression to investigate how the odds of super-use and under-use varied by practice size, type, urban or rural location, and geographic region. Seventy-three percent of practices were not using EHR technologies to their full capability, and nearly 40% were classified as under-users. Under-user practices were more likely to be of smaller size, situated in the West, and located outside a metropolitan area. To achieve the broader benefits of the EHR and health IT, health systems and policy makers need to identify and address barriers to full use of health IT functionalities.

Towards Agile Ontology Maintenance

NASA Astrophysics Data System (ADS)

Luczak-Rösch, Markus

Ontologies are an appropriate means to represent knowledge on the Web. Research on ontology engineering reached practices for an integrative lifecycle support. However, a broader success of ontologies in Web-based information systems remains unreached while the more lightweight semantic approaches are rather successful. We assume, paired with the emerging trend of services and microservices on the Web, new dynamic scenarios gain momentum in which a shared knowledge base is made available to several dynamically changing services with disparate requirements. Our work envisions a step towards such a dynamic scenario in which an ontology adapts to the requirements of the accessing services and applications as well as the user's needs in an agile way and reduces the experts' involvement in ontology maintenance processes.

Drug addicts seeking treatment after the Iranian Revolution: a clinic-based study.

PubMed

Dalvand, S; Agahi, C; Spencer, C

1984-09-01

A sample survey of 200 addicts attending the Rehabilitation Centre at Shiraz was conducted after the 1979 Iranian Revolution had disrupted both drug supply and addict treatment programmes. The study showed that clinics were, after the revolution, seeing a broader social range of addicts than before; and that action by the authorities was bringing many recently-addicted individuals to clinics. Heroin use predominated among those who were urban residents, whilst villagers were more likely to be opium users. The survey also sought the addicts' perceptions of the reasons for their initiation and addiction.

Interaction design challenges and solutions for ALMA operations monitoring and control

NASA Astrophysics Data System (ADS)

Pietriga, Emmanuel; Cubaud, Pierre; Schwarz, Joseph; Primet, Romain; Schilling, Marcus; Barkats, Denis; Barrios, Emilio; Vila Vilaro, Baltasar

2012-09-01

The ALMA radio-telescope, currently under construction in northern Chile, is a very advanced instrument that presents numerous challenges. From a software perspective, one critical issue is the design of graphical user interfaces for operations monitoring and control that scale to the complexity of the system and to the massive amounts of data users are faced with. Early experience operating the telescope with only a few antennas has shown that conventional user interface technologies are not adequate in this context. They consume too much screen real-estate, require many unnecessary interactions to access relevant information, and fail to provide operators and astronomers with a clear mental map of the instrument. They increase extraneous cognitive load, impeding tasks that call for quick diagnosis and action. To address this challenge, the ALMA software division adopted a user-centered design approach. For the last two years, astronomers, operators, software engineers and human-computer interaction researchers have been involved in participatory design workshops, with the aim of designing better user interfaces based on state-of-the-art visualization techniques. This paper describes the process that led to the development of those interface components and to a proposal for the science and operations console setup: brainstorming sessions, rapid prototyping, joint implementation work involving software engineers and human-computer interaction researchers, feedback collection from a broader range of users, further iterations and testing.

Adherence and Persistence Among Statin Users Aged 65 Years and Over: A Systematic Review and Meta-analysis.

PubMed

Ofori-Asenso, Richard; Jakhu, Avtar; Zomer, Ella; Curtis, Andrea J; Korhonen, Maarit Jaana; Nelson, Mark; Gambhir, Manoj; Tonkin, Andrew; Liew, Danny; Zoungas, Sophia

2018-05-09

Older people (aged ≥ 65 years) have distinctive challenges with medication adherence. However, adherence and persistence patterns among older statin users have not been comprehensively reviewed. As part of a broader systematic review, we searched Medline, Embase, PsycINFO, CINAHL, Database of Abstracts of Reviews of Effects, CENTRAL, and the National Health Service Economic Evaluation Database through December 2016 for English articles reporting adherence and/or persistence among older statin users. Data were analyzed via descriptive methods and meta-analysis using random-effect modeling. Data from more than 3 million older statin users in 82 studies conducted in over 40 countries were analyzed. At 1-year follow-up, 59.7% (primary prevention 47.9%; secondary prevention 62.3%) of users were adherent (medication possession ratio [MPR] or proportion of days covered [PDC] ≥ 80%). For both primary and secondary prevention subjects, 1-year adherence was worse among individuals aged more than 75 years than those aged 65-75 years. At 3 and ≥10 years, 55.3% and 28.4% of users were adherent, respectively. The proportion of users persistent at 1-year was 76.7% (primary prevention 76.0%; secondary prevention 82.6%). Additionally, 68.1% and 61.2% of users were persistent at 2 and 4 years, respectively. Among new statin users, 48.2% were nonadherent and 23.9% discontinued within the first year. The proportion of statin users who were adherent based on self-report was 85.5%. There is poor short and long term adherence and persistence among older statin users. Strategies to improve adherence and reduce discontinuation are needed if the intended cardiovascular benefits of statin treatment are to be realized.

Leveraging Social Links for Trust and Privacy in Networks

NASA Astrophysics Data System (ADS)

Cutillo, Leucio Antonio; Molva, Refik; Strufe, Thorsten

Existing on-line social networks (OSN) such as Facebook suffer from several weaknesses regarding privacy and security due to their inherent handling of personal data. As pointed out in [4], a preliminary analysis of existing OSNs shows that they are subject to a number of vulnerabilities, ranging from cloning legitimate users to sybil attacks through privacy violations. Starting from these OSN vulnerabilities as the first step of a broader research activity, we came up with a new approach that is very promising in re-visiting security and privacy problems in distributed systems and networks. We suggest a solution that both aims at avoiding any centralized control and leverages on the real life trust between users, that is part of the social network application itself. An anonymization technique based on multi-hop routing among trusted nodes guarantees privacy in data access and, generally speaking, in all the OSN operations.

User-oriented evaluation of mechanical single-channel axial pipettes.

PubMed

Sormunen, Erja; Nevala, Nina

2013-09-01

Hand tools should be designed so that they are comfortable to use, fit the hand and are user-oriented. Six different manual, single-channel axial pipettes were evaluated for such objective outcomes as muscular activity, wrist postures and efficiency, as well as for subjective outcomes concerning self-assessed features of pipette usability and musculoskeletal strain. Ten experienced laboratory employees volunteered for the study. The results showed that light and short pipettes with better tool comfort resulted in reduced muscular activity and perceived musculoskeletal strain when they were compared with a long and heavy pipette. There were no differences in the efficiency between the different pipettes. Combining both the objective and subjective measures enabled a broader evaluation of product usability. The results of this study can be used both in product development and as information on which to base the purchase of new pipettes for laboratory work. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

ChimericSeq: An open-source, user-friendly interface for analyzing NGS data to identify and characterize viral-host chimeric sequences.

PubMed

Shieh, Fwu-Shan; Jongeneel, Patrick; Steffen, Jamin D; Lin, Selena; Jain, Surbhi; Song, Wei; Su, Ying-Hsiu

2017-01-01

Identification of viral integration sites has been important in understanding the pathogenesis and progression of diseases associated with particular viral infections. The advent of next-generation sequencing (NGS) has enabled researchers to understand the impact that viral integration has on the host, such as tumorigenesis. Current computational methods to analyze NGS data of virus-host junction sites have been limited in terms of their accessibility to a broad user base. In this study, we developed a software application (named ChimericSeq), that is the first program of its kind to offer a graphical user interface, compatibility with both Windows and Mac operating systems, and optimized for effectively identifying and annotating virus-host chimeric reads within NGS data. In addition, ChimericSeq's pipeline implements custom filtering to remove artifacts and detect reads with quantitative analytical reporting to provide functional significance to discovered integration sites. The improved accessibility of ChimericSeq through a GUI interface in both Windows and Mac has potential to expand NGS analytical support to a broader spectrum of the scientific community.

ChimericSeq: An open-source, user-friendly interface for analyzing NGS data to identify and characterize viral-host chimeric sequences

PubMed Central

Shieh, Fwu-Shan; Jongeneel, Patrick; Steffen, Jamin D.; Lin, Selena; Jain, Surbhi; Song, Wei

2017-01-01

Identification of viral integration sites has been important in understanding the pathogenesis and progression of diseases associated with particular viral infections. The advent of next-generation sequencing (NGS) has enabled researchers to understand the impact that viral integration has on the host, such as tumorigenesis. Current computational methods to analyze NGS data of virus-host junction sites have been limited in terms of their accessibility to a broad user base. In this study, we developed a software application (named ChimericSeq), that is the first program of its kind to offer a graphical user interface, compatibility with both Windows and Mac operating systems, and optimized for effectively identifying and annotating virus-host chimeric reads within NGS data. In addition, ChimericSeq’s pipeline implements custom filtering to remove artifacts and detect reads with quantitative analytical reporting to provide functional significance to discovered integration sites. The improved accessibility of ChimericSeq through a GUI interface in both Windows and Mac has potential to expand NGS analytical support to a broader spectrum of the scientific community. PMID:28829778

Reaching users at local scales: insights into the value of forest inventory information for education and outreach and the potential for an effective partnership between FIA, cooperative extension, and state and national conservation education partners

Treesearch

Rachel Riemann

2015-01-01

Forest information is desired for broader applications than we typically serve. Among those underserved users are the education and outreach communities. These groups are actively trying to engage and teach both youth and adults in areas such as GIS/spatial analysis, natural resource education, general math/science, invasive species, climate change, water quality, and...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alstone, Peter; Jacobson, Arne; Mills, Evan

Efforts to promote rechargeable electric lighting as a replacement for fuel-based light sources in developing countries are typically predicated on the notion that lighting service levels can be maintained or improved while reducing the costs and environmental impacts of existing practices. However, the extremely low incomes of those who depend on fuel-based lighting create a need to balance the hypothetically possible or desirable levels of light with those that are sufficient and affordable. In a pilot study of four night vendors in Kenya, we document a field technique we developed to simultaneously measure the effectiveness of lighting service provided bymore » a lighting system and conduct a survey of lighting service demand by end-users. We took gridded illuminance measurements across each vendor's working and selling area, with users indicating the sufficiency of light at each point. User light sources included a mix of kerosene-fueled hurricane lanterns, pressure lamps, and LED lanterns.We observed illuminance levels ranging from just above zero to 150 lux. The LED systems markedly improved the lighting service levels over those provided by kerosene-fueled hurricane lanterns. Users reported that the minimum acceptable threshold was about 2 lux. The results also indicated that the LED lamps in use by the subjects did not always provide sufficient illumination over the desired retail areas. Our sample size is much too small, however, to reach any conclusions about requirements in the broader population. Given the small number of subjects and very specific type of user, our results should be regarded as indicative rather than conclusive. We recommend replicating the method at larger scales and across a variety of user types and contexts. Policymakers should revisit the subject of recommended illuminance levels regularly as LED technology advances and the price/service balance point evolves.« less

“We’re Supposed to Be Asleep?” Vigilance, Paranoia, and the Alert Methamphetamine User

PubMed Central

McKenna, Stacey A.

2015-01-01

The stimulant “benefits” of amphetamine and its derivative, methamphetamine, have endured since the drugs first became popular nearly a century ago. The concepts of increasing energy for functional purposes related to work and productivity have been well studied. However, the broader idea of increased alertness, and what this means in the lives of users, has not yet been sufficiently examined. This article draws from ongoing research with active methamphetamine users to explore the perceived benefits, drawbacks, and meanings of remaining alert—awake and vigilant—while most of the world sleeps. The experiences of several users are situated in the contexts of sociostructural and mental health issues that shape cycles of use and meanings of addiction. PMID:26366049

Transitioning Earth Remote Sensing Data to Benefit Society: A Paradigm for a Center of Excellence

NASA Technical Reports Server (NTRS)

Jedlovec, Gary; Bjorgo, Einar; Burn, Anthony

2015-01-01

Over the past decade there has been a substantial increase in the number of Earth remote sensing satellites launched for research and operational usage and numerous others planned by the international community. These satellites have been used to varying degrees by their supporting agencies for weather and environmental monitoring, climate studies, disaster monitoring and response, and other humanitarian activities. While there are success stories on useful applications of remote sensing data, the broader use of these satellite assets by other organizations and entities has been limited for a number of reasons including lack of data services, data dissemination issues, and a general failure to engage the broader end user community with useful data access and knowledge of how to use the data and products. This paper describes some of these current limitations on the broader use of Earth remote sensing data by the international community and describes the concept of a general "Center of Excellence" to facilitate the development, transition, and utilization of these Earth remote sensing observations by the broader international community.

Effects of user fee exemptions on the provision and use of maternal health services: a review of literature.

PubMed

Hatt, Laurel E; Makinen, Marty; Madhavan, Supriya; Conlon, Claudia M

2013-12-01

User fee removal has been put forward as an approach to increasing priority health service utilization, reducing impoverishment, and ultimately reducing maternal and neonatal mortality. However, user fees are a source of facility revenue in many low-income countries, often used for purchasing drugs and supplies and paying incentives to health workers. This paper reviews evidence on the effects of user fee exemptions on maternal health service utilization, service provision, and outcomes, including both supply-side and demand-side effects. We reviewed 19 peer-reviewed research articles addressing user fee exemptions and maternal health services or outcomes published since 1990. Studies were identified through a USAID-commissioned call for evidence, key word search, and screening process. Teams of reviewers assigned criteria-based quality scores to each paper and prepared structured narrative reviews. The grade of the evidence was found to be relatively weak, mainly from short-term, non-controlled studies. The introduction of user fee exemptions appears to have resulted in increased rates of facility-based deliveries and caesarean sections in some contexts. Impacts on maternal and neonatal mortality have not been conclusively demonstrated; exemptions for delivery care may contribute to modest reductions in institutional maternal mortality but the evidence is very weak. User fee exemptions were found to have negative, neutral, or inconclusive effects on availability of inputs, provider motivation, and quality of services. The extent to which user fee revenue lost by facilities is replaced can directly affect service provision and may have unintended consequences for provider motivation. Few studies have looked at the equity effects of fee removal, despite clear evidence that fees disproportionately burden the poor. This review highlights potential and documented benefits (increased use of maternity services) as well as risks (decreased provider motivation and quality) of user fee exemption policies for maternal health services. Governments should link user fee exemption policies with the replacement of lost revenue for facilities as well as broader health system improvements, including facility upgrades, ensured supply of needed inputs, and improved human resources for health. Removing user fees may increase uptake but will not reduce mortality proportionally if the quality of facility-based care is poor. More rigorous evaluations of both demand- and supply-side effects of mature fee exemption programmes are needed.

US Topo: Topographic Maps for the Nation

USGS Publications Warehouse

Hytes, Patricia L.

2009-01-01

US Topo is the next generation of topographic maps from the U.S. Geological Survey (USGS). Arranged in the familiar 7.5-minute quadrangle format, digital US Topo maps are designed to look and feel (and perform) like the traditional paper topographic maps for which the USGS is so well known. In contrast to paper-based maps, US Topo maps provide modern technical advantages that support faster, wider public distribution and enable basic, on-screen geographic analysis for all users. US Topo maps are available free on the Web. Each map quadrangle is constructed in GeoPDF? format from key layers of geographic data (orthoimagery, roads, geographic names, topographic contours, and hydrographic features) found in The National Map. US Topo quadrangles can be printed from personal computers or plotters as complete, full-sized, maps or in customized sections, in a user-desired specific format. Paper copies of the maps can also be purchased from the USGS Store. Download links and a users guide are featured on the US Topo Web site. US Topo users can turn geographic data layers on and off as needed; they can zoom in and out to highlight specific features or see a broader area. File size for each digital 7.5-minute quadrangle, about 15-20 megabytes, is suitable for most users. Associated electronic tools for geographic analysis are available free for download.

Interactive Schematic Integration Within the Propellant System Modeling Environment

NASA Technical Reports Server (NTRS)

Coote, David; Ryan, Harry; Burton, Kenneth; McKinney, Lee; Woodman, Don

2012-01-01

Task requirements for rocket propulsion test preparations of the test stand facilities drive the need to model the test facility propellant systems prior to constructing physical modifications. The Propellant System Modeling Environment (PSME) is an initiative designed to enable increased efficiency and expanded capabilities to a broader base of NASA engineers in the use of modeling and simulation (M&S) technologies for rocket propulsion test and launch mission requirements. PSME will enable a wider scope of users to utilize M&S of propulsion test and launch facilities for predictive and post-analysis functionality by offering a clean, easy-to-use, high-performance application environment.

Engaging the broader community in biodiversity research: the concept of the COMBER pilot project for divers in ViBRANT

PubMed Central

Arvanitidis, Christos; Faulwetter, Sarah; Chatzigeorgiou, Georgios; Penev, Lyubomir; Bánki, Olaf; Dailianis, Thanos; Pafilis, Evangelos; Kouratoras, Michail; Chatzinikolaou, Eva; Fanini, Lucia; Vasileiadou, Aikaterini; Pavloudi, Christina; Vavilis, Panagiotis; Koulouri, Panayota; Dounas, Costas

2011-01-01

Abstract This paper discusses the design and implementation of a citizen science pilot project, COMBER (Citizens’ Network for the Observation of Marine BiodivERsity, http://www.comber.hcmr.gr), which has been initiated under the ViBRANT EU e-infrastructure. It is designed and implemented for divers and snorkelers who are interested in participating in marine biodiversity citizen science projects. It shows the necessity of engaging the broader community in the marine biodiversity monitoring and research projects, networks and initiatives. It analyses the stakeholders, the industry and the relevant markets involved in diving activities and their potential to sustain these activities. The principles, including data policy and rewards for the participating divers through their own data, upon which this project is based are thoroughly discussed. The results of the users analysis and lessons learned so far are presented. Future plans include promotion, links with citizen science web developments, data publishing tools, and development of new scientific hypotheses to be tested by the data collected so far. PMID:22207815

Harnessing complexity: taking advantage of context and relationships in dissemination of school-based interventions.

PubMed

Butler, Helen; Bowes, Glenn; Drew, Sarah; Glover, Sara; Godfrey, Celia; Patton, George; Trafford, Lea; Bond, Lyndal

2010-03-01

Schools and school systems are increasingly asked to use evidence-based strategies to promote the health and well-being of students. The dissemination of school-based health promotion research, however, offers particular challenges to conventional approaches to dissemination. Schools and education systems are multifaceted organizations that sit within constantly shifting broader contexts. This article argues that health promotion dissemination needs to be rethought for school communities as complex systems and that this requires understanding and harnessing the dynamic ecology of the sociopolitical context. In developing this argument, the authors draw on their experience of the dissemination process of a multilevel school-based intervention in a complex educational context. Building on this experience, they argue for the need to move beyond conventional dissemination strategies to a focus on active partnerships between developers and users of school-based intervention research and offer a conceptual tool for planning dissemination.

Understanding USGS user needs and Earth observing data use for decision making

NASA Astrophysics Data System (ADS)

Wu, Z.

2016-12-01

US Geological Survey (USGS) initiated the Requirements, Capabilities and Analysis for Earth Observations (RCA-EO) project in the Land Remote Sensing (LRS) program, collaborating with the National Oceanic and Atmospheric Administration (NOAA) to jointly develop the supporting information infrastructure - The Earth Observation Requirements Evaluation Systems (EORES). RCA-EO enables us to collect information on current data products and projects across the USGS and evaluate the impacts of Earth observation data from all sources, including spaceborne, airborne, and ground-based platforms. EORES allows users to query, filter, and analyze usage and impacts of Earth observation data at different organizational level within the bureau. We engaged over 500 subject matter experts and evaluated more than 1000 different Earth observing data sources and products. RCA-EO provides a comprehensive way to evaluate impacts of Earth observing data on USGS mission areas and programs through the survey of 345 key USGS products and services. We paid special attention to user feedback about Earth observing data to inform decision making on improving user satisfaction. We believe the approach and philosophy of RCA-EO can be applied in much broader scope to derive comprehensive knowledge of Earth observing systems impacts and usage and inform data products development and remote sensing technology innovation.

Relationships between Emotional States and Emoticons in Mobile Phone Email Communication in Japan

ERIC Educational Resources Information Center

Kato, Shogo; Kato, Yuuki; Scott, Douglass

2009-01-01

Three related studies conducted on the role of emotional transfer in email messages were studied in order to better understand Japanese college students' online communications and their broader participation in online communications. The first study investigated users' initiatives in preventing emotional misunderstandings when sending email.…

Emerging Standards for Medical Logic

PubMed Central

Clayton, Paul D.; Hripcsak, George; Pryor, T. Allan

1990-01-01

Sharing medical logic has traditionally occurred in the form of lectures, conversations, books and journals. As knowledge based computer systems have demonstrated their utility in the health care arena, individuals have pondered the best way to transfer knowledge in a computer based representation (1). A simple representation which allows the knowledge to be shared can be constructed when the knowledge base is modular. Within this representation, units have been named Medical Logic Modules (MLM's) and a syntax has emerged which would allow multiple users to create, criticize, and share those types of medical logic which can be represented in this format. In this paper we talk about why standards exist and why they emerge in some areas and not in others. The appropriateness of using the proposed standards for medical logic modules is then examined against this broader context.

A validation study regarding a generative approach in choosing appropriate colors for impaired users.

PubMed

Troiano, Luigi; Birtolo, Cosimo; Armenise, Roberto

2016-01-01

In many circumstances, concepts, ideas and emotions are mainly conveyed by colors. Color vision disorders can heavily limit the user experience in accessing Information Society. Therefore, color vision impairments should be taken into account in order to make information and services accessible to a broader audience. The task is not easy for designers that generally are not affected by any color vision disorder. In any case, the design of accessible user interfaces should not lead to to boring color schemes. The selection of appealing and harmonic color combinations should be preserved. In past research we investigated a generative approach led by evolutionary computing in supporting interface designers to make colors accessible to impaired users. This approach has also been followed by other authors. The contribution of this paper is to provide an experimental validation to the claim that this approach is actually beneficial to designers and users.

Hydrological models as web services: Experiences from the Environmental Virtual Observatory project

NASA Astrophysics Data System (ADS)

Buytaert, W.; Vitolo, C.; Reaney, S. M.; Beven, K.

2012-12-01

Data availability in environmental sciences is expanding at a rapid pace. From the constant stream of high-resolution satellite images to the local efforts of citizen scientists, there is an increasing need to process the growing stream of heterogeneous data and turn it into useful information for decision-making. Environmental models, ranging from simple rainfall - runoff relations to complex climate models, can be very useful tools to process data, identify patterns, and help predict the potential impact of management scenarios. Recent technological innovations in networking, computing and standardization may bring a new generation of interactive models plugged into virtual environments closer to the end-user. They are the driver of major funding initiatives such as the UK's Virtual Observatory program, and the U.S. National Science Foundation's Earth Cube. In this study we explore how hydrological models, being an important subset of environmental models, have to be adapted in order to function within a broader environment of web-services and user interactions. Historically, hydrological models have been developed for very different purposes. Typically they have a rigid model structure, requiring a very specific set of input data and parameters. As such, the process of implementing a model for a specific catchment requires careful collection and preparation of the input data, extensive calibration and subsequent validation. This procedure seems incompatible with a web-environment, where data availability is highly variable, heterogeneous and constantly changing in time, and where the requirements of end-users may be not necessarily align with the original intention of the model developer. We present prototypes of models that are web-enabled using the web standards of the Open Geospatial Consortium, and implemented in online decision-support systems. We identify issues related to (1) optimal use of available data; (2) the need for flexible and adaptive structures; (3) quantification and communication of uncertainties. Lastly, we present some road maps to address these issues and discuss them in the broader context of web-based data processing and "big data" science.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tracy, Jenny; Jacobson, Arne; Mills, Evan

Flashlights that use LED technology have quickly emerged as the dominant source of portable lighting in Kenya. While flashlights do not normally provide a substitute for kerosene and other highly inefficient fuels, they are an important early manifestation of LED lighting in the developing world that can serve as a platform - or deterrent - to the diffusion of the technology into the broader off-grid lighting market. The lead acid batteries embedded in flashlights also represent an important source of hazardous waste, and flashlight durability is thus an important determinant of the rate of waste disposal. Low-cost LED flashlights withmore » prices from $1 to $4 are now widely available in shops and markets throughout Kenya. The increased penetration of LED technology in the flashlight market is significant, as over half of all Kenyan households report owning a flashlight (Kamfor, 2002). While this shift from conventional incandescent technology to modern LEDs may appear to be a promising development, end users that our research team interviewed expressed a number of complaints about the quality and performance of these new flashlights. This raises concerns about the interests of low-income flashlight users, and it may also indicate the onset of a broader market spoiling effect for off-grid lighting products based on LED technology (Mills and Jacobson, 2008; Lighting Africa, 2007). The quality of low-cost LED flashlights can contribute to market spoiling because these products appear to represent the first contact that most Kenyans have with LED technology. In this report, our team uses interviews with 46 end users of flashlights to collect information about their experiences, perceptions, and preferences. We focus especially on highlighting common complaints from respondents about the flashlights that they have used, as well as on noting the features that they indicated were important when evaluating the quality of a flashlight. In previous laboratory tests, researchers from our team found a wide range of quality and performance among battery powered LED lights (Granderson, et al. 2008).« less

[A Terahertz Spectral Database Based on Browser/Server Technique].

PubMed

Zhang, Zhuo-yong; Song, Yue

2015-09-01

With the solution of key scientific and technical problems and development of instrumentation, the application of terahertz technology in various fields has been paid more and more attention. Owing to the unique characteristic advantages, terahertz technology has been showing a broad future in the fields of fast, non-damaging detections, as well as many other fields. Terahertz technology combined with other complementary methods can be used to cope with many difficult practical problems which could not be solved before. One of the critical points for further development of practical terahertz detection methods depends on a good and reliable terahertz spectral database. We developed a BS (browser/server) -based terahertz spectral database recently. We designed the main structure and main functions to fulfill practical requirements. The terahertz spectral database now includes more than 240 items, and the spectral information was collected based on three sources: (1) collection and citation from some other abroad terahertz spectral databases; (2) collected from published literatures; and (3) spectral data measured in our laboratory. The present paper introduced the basic structure and fundament functions of the terahertz spectral database developed in our laboratory. One of the key functions of this THz database is calculation of optical parameters. Some optical parameters including absorption coefficient, refractive index, etc. can be calculated based on the input THz time domain spectra. The other main functions and searching methods of the browser/server-based terahertz spectral database have been discussed. The database search system can provide users convenient functions including user registration, inquiry, displaying spectral figures and molecular structures, spectral matching, etc. The THz database system provides an on-line searching function for registered users. Registered users can compare the input THz spectrum with the spectra of database, according to the obtained correlation coefficient one can perform the searching task very fast and conveniently. Our terahertz spectral database can be accessed at http://www.teralibrary.com. The proposed terahertz spectral database is based on spectral information so far, and will be improved in the future. We hope this terahertz spectral database can provide users powerful, convenient, and high efficient functions, and could promote the broader applications of terahertz technology.

Environmental Impacts of the Use of Ecosystem Services: Case Study of Birdwatching

NASA Astrophysics Data System (ADS)

Kronenberg, Jakub

2014-09-01

The main reason for promoting the concept of ecosystem services lies in its potential to contribute to environmental conservation. Highlighting the benefits derived from ecosystems fosters an understanding of humans' dependence on nature, as users of ecosystem services. However, the act of using ecosystem services may not be environmentally neutral. As with the use of products and services generated within an economy, the use of ecosystem services may lead to unintended environmental consequences throughout the `ecosystem services supply chain.' This article puts forward a framework for analyzing environmental impacts related to the use of ecosystem services, indicating five categories of impact: (1) direct impacts (directly limiting the service's future availability); and four categories of indirect impacts, i.e., on broader ecosystem structures and processes, which can ultimately also affect the initial service: (2) impacts related to managing ecosystems to maximize the delivery of selected services (affecting ecosystems' capacity to provide other services); (3) impacts associated with accessing ecosystems to use their services (affecting other ecosystem components); (4) additional consumption of products, infrastructure or services required to use a selected ecosystem service, and their life-cycle environmental impacts; and (5) broader impacts on the society as a whole (environmental awareness of ecosystem service users and other stakeholders). To test the usefulness of this framework, the article uses the case study of birdwatching, which demonstrates all of the above categories of impacts. The article justifies the need for a broader consideration of environmental impacts related to the use of ecosystem services.

Architectural Principles and Experimentation of Distributed High Performance Virtual Clusters

ERIC Educational Resources Information Center

Younge, Andrew J.

2016-01-01

With the advent of virtualization and Infrastructure-as-a-Service (IaaS), the broader scientific computing community is considering the use of clouds for their scientific computing needs. This is due to the relative scalability, ease of use, advanced user environment customization abilities, and the many novel computing paradigms available for…

Big Earth Data Initiative: Metadata Improvement: Case Studies

NASA Technical Reports Server (NTRS)

Kozimor, John; Habermann, Ted; Farley, John

2016-01-01

Big Earth Data Initiative (BEDI) The Big Earth Data Initiative (BEDI) invests in standardizing and optimizing the collection, management and delivery of U.S. Government's civil Earth observation data to improve discovery, access use, and understanding of Earth observations by the broader user community. Complete and consistent standard metadata helps address all three goals.

Streaming Media Seminar--Effective Development and Distribution of Streaming Multimedia in Education

ERIC Educational Resources Information Center

Mainhart, Robert; Gerraughty, James; Anderson, Kristine M.

2004-01-01

Concisely defined, "streaming media" is moving video and/or audio transmitted over the Internet for immediate viewing/listening by an end user. However, at Saint Francis University's Center of Excellence for Remote and Medically Under-Served Areas (CERMUSA), streaming media is approached from a broader perspective. The working definition includes…

User Guidelines and Best Practices for CASL VUQ Analysis Using Dakota.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, Brian M.; Coleman, Kayla; Hooper, Russell

2016-11-01

Sandia's Dakota software (available at http://dakota.sandia.gov) supports science and engineering transformation through advanced exploration of simulations. Specifically it manages and analyzes ensembles of simulations to provide broader and deeper perspective for analysts and decision makers. This enables them to enhance understanding of risk, improve products, and assess simulation credibility.

University Governance: Governing Bodies as Providers and Users of Annual Reports

ERIC Educational Resources Information Center

Dixon, Keith; Coy, David

2007-01-01

Where members of governing bodies of universities stand in relation to their institution's annual reports is discussed in the broader context of trends in university governance. Data were collected from members of the governing councils of New Zealand's eight universities using questionnaire surveys in 1993 and 2001. During this interval, a marked…

The Information Literacy Imperative in Higher Education

ERIC Educational Resources Information Center

Wiebe, Todd J.

2016-01-01

This article describes information literacy as a liberal art that draws on a repertoire of critical inquiry skills. At the philosophical level, librarians believe that information literacy is a fundamental part of students' broader skill set that will help them be effective and responsible users and creators of information, both in college and…

Use of nonintrusive sensor-based information and communication technology for real-world evidence for clinical trials in dementia.

PubMed

Teipel, Stefan; König, Alexandra; Hoey, Jesse; Kaye, Jeff; Krüger, Frank; Robillard, Julie M; Kirste, Thomas; Babiloni, Claudio

2018-06-21

Cognitive function is an important end point of treatments in dementia clinical trials. Measuring cognitive function by standardized tests, however, is biased toward highly constrained environments (such as hospitals) in selected samples. Patient-powered real-world evidence using information and communication technology devices, including environmental and wearable sensors, may help to overcome these limitations. This position paper describes current and novel information and communication technology devices and algorithms to monitor behavior and function in people with prodromal and manifest stages of dementia continuously, and discusses clinical, technological, ethical, regulatory, and user-centered requirements for collecting real-world evidence in future randomized controlled trials. Challenges of data safety, quality, and privacy and regulatory requirements need to be addressed by future smart sensor technologies. When these requirements are satisfied, these technologies will provide access to truly user relevant outcomes and broader cohorts of participants than currently sampled in clinical trials. Copyright © 2018. Published by Elsevier Inc.

Bringing Web 2.0 to bioinformatics.

PubMed

Zhang, Zhang; Cheung, Kei-Hoi; Townsend, Jeffrey P

2009-01-01

Enabling deft data integration from numerous, voluminous and heterogeneous data sources is a major bioinformatic challenge. Several approaches have been proposed to address this challenge, including data warehousing and federated databasing. Yet despite the rise of these approaches, integration of data from multiple sources remains problematic and toilsome. These two approaches follow a user-to-computer communication model for data exchange, and do not facilitate a broader concept of data sharing or collaboration among users. In this report, we discuss the potential of Web 2.0 technologies to transcend this model and enhance bioinformatics research. We propose a Web 2.0-based Scientific Social Community (SSC) model for the implementation of these technologies. By establishing a social, collective and collaborative platform for data creation, sharing and integration, we promote a web services-based pipeline featuring web services for computer-to-computer data exchange as users add value. This pipeline aims to simplify data integration and creation, to realize automatic analysis, and to facilitate reuse and sharing of data. SSC can foster collaboration and harness collective intelligence to create and discover new knowledge. In addition to its research potential, we also describe its potential role as an e-learning platform in education. We discuss lessons from information technology, predict the next generation of Web (Web 3.0), and describe its potential impact on the future of bioinformatics studies.

BioLayout(Java): versatile network visualisation of structural and functional relationships.

PubMed

Goldovsky, Leon; Cases, Ildefonso; Enright, Anton J; Ouzounis, Christos A

2005-01-01

Visualisation of biological networks is becoming a common task for the analysis of high-throughput data. These networks correspond to a wide variety of biological relationships, such as sequence similarity, metabolic pathways, gene regulatory cascades and protein interactions. We present a general approach for the representation and analysis of networks of variable type, size and complexity. The application is based on the original BioLayout program (C-language implementation of the Fruchterman-Rheingold layout algorithm), entirely re-written in Java to guarantee portability across platforms. BioLayout(Java) provides broader functionality, various analysis techniques, extensions for better visualisation and a new user interface. Examples of analysis of biological networks using BioLayout(Java) are presented.

User Guidelines and Best Practices for CASL VUQ Analysis Using Dakota.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, Brian M.; Coleman, Kayla; Hooper, Russell

2016-11-01

Sandia's Dakota software (available at http://dakota.sandia.gov) supports science and engineering transformation through advanced exploration of simulations. Specifically, it manages and analyzes ensembles of simulations to provide broader and deeper perspective for analysts and decision makers. This enables them to enhance understanding of risk, improve products, and assess simulation credibility. This manual offers Consortium for Advanced Simulation of Light Water Reactors (LWRs) (CASL) partners a guide to conducting Dakota-based VUQ studies for CASL problems. It motivates various classes of Dakota methods and includes examples of their use on representative application problems. On reading, a CASL analyst should understand why and howmore » to apply Dakota to a simulation problem.« less

Visualization in simulation tools: requirements and a tool specification to support the teaching of dynamic biological processes.

PubMed

Jørgensen, Katarina M; Haddow, Pauline C

2011-08-01

Simulation tools are playing an increasingly important role behind advances in the field of systems biology. However, the current generation of biological science students has either little or no experience with such tools. As such, this educational glitch is limiting both the potential use of such tools as well as the potential for tighter cooperation between the designers and users. Although some simulation tool producers encourage their use in teaching, little attempt has hitherto been made to analyze and discuss their suitability as an educational tool for noncomputing science students. In general, today's simulation tools assume that the user has a stronger mathematical and computing background than that which is found in most biological science curricula, thus making the introduction of such tools a considerable pedagogical challenge. This paper provides an evaluation of the pedagogical attributes of existing simulation tools for cell signal transduction based on Cognitive Load theory. Further, design recommendations for an improved educational simulation tool are provided. The study is based on simulation tools for cell signal transduction. However, the discussions are relevant to a broader biological simulation tool set.

Young People's Political Participation in the 2011 Parliamentary Elections

ERIC Educational Resources Information Center

Loginova, K.

2014-01-01

Characteristics political behavior among Russian youth can be seen as part of a broader trend toward the erosion of the classical divisions in Russian society. Research shows division between those who support and those who condemn the authorities, and between those who are active users of the Internet and who take part in discussions, and those…

Characterisation of User-Defined Health Status in Older Adults with Intellectual Disabilities

ERIC Educational Resources Information Center

Starr, J. M.; Marsden, L.

2008-01-01

Background: Older adults with Intellectual Disabilities (ID) have an excess disease burden that standard health assessments are designed to detect. Older adults with ID have a broader concept of health with dimensions of well being in addition to absence of disease in line with the World Health Organization's health definition. We sought to…

A TCP/IP framework for ethernet-based measurement, control and experiment data distribution

NASA Astrophysics Data System (ADS)

Ocaya, R. O.; Minny, J.

2010-11-01

A complete modular but scalable TCP/IP based scientific instrument control and data distribution system has been designed and realized. The system features an IEEE 802.3 compliant 10 Mbps Medium Access Controller (MAC) and Physical Layer Device that is suitable for the full-duplex monitoring and control of various physically widespread measurement transducers in the presence of a local network infrastructure. The cumbersomeness of exchanging and synchronizing data between the various transducer units using physical storage media led to the choice of TCP/IP as a logical alternative. The system and methods developed are scalable for broader usage over the Internet. The system comprises a PIC18f2620 and ENC28j60 based hardware and a software component written in C, Java/Javascript and Visual Basic.NET programming languages for event-level monitoring and browser user-interfaces respectively. The system exchanges data with the host network through IPv4 packets requested and received on a HTTP page. It also responds to ICMP echo, UDP and ARP requests through a user selectable integrated DHCP and static IPv4 address allocation scheme. The round-trip time, throughput and polling frequency are estimated and reported. A typical application to temperature monitoring and logging is also presented.

Stigma, Social Structure, and the Biomedical Framework: Exploring the Stigma Experiences of Inpatient Service Users in Two Belgian Psychiatric Hospitals.

PubMed

Sercu, Charlotte; Bracke, Piet

2017-07-01

The study discusses the stigma experiences of service users in mental health care, within the debate on the role of the biomedical framework for mental health care and power relations in society. Interview data of inpatient users ( n = 42) and care providers ( n = 43) from two Belgian psychiatric hospitals were analyzed using a constructivist grounded theory approach: Findings offer insight into how stigma experiences are affected by social structure. Stigma seemed to be related to the relation between care providers and service users their social position. The concept "mental health literacy" is used to frame this finding. In paying attention to the specific cultural and normative context, which influences the relationship between mental health literacy and stigma, it is further possible to cast some light on the meaning of the biomedical model for the construction and maintenance of power relations in mental health care and broader society.

Bringing a Realistic Global Climate Modeling Experience to a Broader Audience

NASA Astrophysics Data System (ADS)

Sohl, L. E.; Chandler, M. A.; Zhou, J.

2010-12-01

EdGCM, the Educational Global Climate Model, was developed with the goal of helping students learn about climate change and climate modeling by giving them the ability to run a genuine NASA global climate model (GCM) on a desktop computer. Since EdGCM was first publicly released in January 2005, tens of thousands of users on seven continents have downloaded the software. EdGCM has been utilized by climate science educators from middle school through graduate school levels, and on occasion even by researchers who otherwise do not have ready access to climate model at national labs in the U.S. and elsewhere. The EdGCM software is designed to walk users through the same process a climate scientist would use in designing and running simulations, and analyzing and visualizing GCM output. Although the current interface design gives users a clear view of some of the complexities involved in using a climate model, it can be daunting for users whose main focus is on climate science rather than modeling per se. As part of the work funded by NASA’s Global Climate Change Education (GCCE) program, we will begin modifications to the user interface that will improve the accessibility of EdGCM to a wider array of users, especially at the middle school and high school levels, by: 1) Developing an automated approach (a “wizard”) to simplify the user experience in setting up new climate simulations; 2) Produce a catalog of “rediscovery experiments” that allow users to reproduce published climate model results, and in some cases compare model projections to real world data; and 3) Enhance distance learning and online learning opportunities through the development of a web-based interface. The prototypes for these modifications will then be presented to educators belonging to an EdGCM Users Group for feedback, so that we can further refine the EdGCM software, and thus deliver the tools and materials educators want and need across a wider range of learning environments.

gPKPDSim: a SimBiology®-based GUI application for PKPD modeling in drug development.

PubMed

Hosseini, Iraj; Gajjala, Anita; Bumbaca Yadav, Daniela; Sukumaran, Siddharth; Ramanujan, Saroja; Paxson, Ricardo; Gadkar, Kapil

2018-04-01

Modeling and simulation (M&S) is increasingly used in drug development to characterize pharmacokinetic-pharmacodynamic (PKPD) relationships and support various efforts such as target feasibility assessment, molecule selection, human PK projection, and preclinical and clinical dose and schedule determination. While model development typically require mathematical modeling expertise, model exploration and simulations could in many cases be performed by scientists in various disciplines to support the design, analysis and interpretation of experimental studies. To this end, we have developed a versatile graphical user interface (GUI) application to enable easy use of any model constructed in SimBiology ® to execute various common PKPD analyses. The MATLAB ® -based GUI application, called gPKPDSim, has a single screen interface and provides functionalities including simulation, data fitting (parameter estimation), population simulation (exploring the impact of parameter variability on the outputs of interest), and non-compartmental PK analysis. Further, gPKPDSim is a user-friendly tool with capabilities including interactive visualization, exporting of results and generation of presentation-ready figures. gPKPDSim was designed primarily for use in preclinical and translational drug development, although broader applications exist. gPKPDSim is a MATLAB ® -based open-source application and is publicly available to download from MATLAB ® Central™. We illustrate the use and features of gPKPDSim using multiple PKPD models to demonstrate the wide applications of this tool in pharmaceutical sciences. Overall, gPKPDSim provides an integrated, multi-purpose user-friendly GUI application to enable efficient use of PKPD models by scientists from various disciplines, regardless of their modeling expertise.

User Preferences for Content, Features, and Style for an App to Reduce Harmful Drinking in Young Adults: Analysis of User Feedback in App Stores and Focus Group Interviews

PubMed Central

Khadjesari, Zarnie; Fincham-Campbell, Stephanie; Deluca, Paolo; Watson, Rod; Drummond, Colin

2016-01-01

Background Electronic screening and brief intervention (eSBI) is effective in reducing weekly alcohol consumption when delivered by a computer. Mobile phone apps demonstrate promise in delivering eSBI; however, few have been designed with an evidence-based and user-informed approach. Objective This study aims to explore from a user perspective, preferences for content, appearance, and operational features to inform the design of a mobile phone app for reducing quantity and frequency of drinking in young adults engaged in harmful drinking (18-30 year olds). Methods Phase 1 included a review of user reviews of available mobile phone apps that support a reduction in alcohol consumption. Apps were identified on iTunes and Google Play and were categorized into alcohol reduction support, entertainment, blood alcohol content measurement (BAC), or other. eSBI apps with ≥18 user reviews were subject to a content analysis, which coded praise, criticism, and recommendations for app content, functionality, and esthetics. Phase 2 included four focus groups with young adults drinking at harmful levels and residing in South London to explore their views on existing eSBI apps and preferences for future content, functionality, and appearance. Detailed thematic analysis of the data was undertaken. Results In Phase 1, of the 1584 apps extracted, 201 were categorized as alcohol reduction, 154 as BAC calculators, 509 as entertainment, and 720 as other. We classified 32 apps as eSBI apps. Four apps had ≥18 user reviews: Change for Life Drinks Tracker, Drinksmeter, Drinkaware, and Alcohol Units Calculator. The highest proportion of content praises were for information and feedback provided in the apps (12/27, 44%), followed by praise for the monitoring features (5/27, 19%). Many (8/12, 67%) criticisms were for the drinking diary; all of these were related to difficulty entering drinks. Over half (18/32, 56%) of functionality criticisms were descriptions of software bugs, and over half of those (10/18, 56%) were for app crashing or freezing. Drinksmeter and Alcohol Units Calculator were the most highly praised apps overall (23/57 and 22/57; 39% of praise overall). In Phase 2, two main themes were identified. The meaningfulness theme reflected how young adults thought apps needed to be tailored to the interests and values of their age group, particularly emphasizing content and feedback around broader health and well-being factors such as exercise, diet, and image. The community theme suggested that young adults want to be able to engage with other app users, both in groups of friends and with online users for motivation and support. Conclusions Targeted and relevant information and feedback, in addition to easy-to-use monitoring tools, were found to be important features of a mobile phone app to support a reduction in drinking. Future app development should consider tailoring all app aspects to the needs of young adults, considering broader well-being monitoring tools and online community functions. PMID:27220371

User Preferences for Content, Features, and Style for an App to Reduce Harmful Drinking in Young Adults: Analysis of User Feedback in App Stores and Focus Group Interviews.

PubMed

Milward, Joanna; Khadjesari, Zarnie; Fincham-Campbell, Stephanie; Deluca, Paolo; Watson, Rod; Drummond, Colin

2016-05-24

Electronic screening and brief intervention (eSBI) is effective in reducing weekly alcohol consumption when delivered by a computer. Mobile phone apps demonstrate promise in delivering eSBI; however, few have been designed with an evidence-based and user-informed approach. This study aims to explore from a user perspective, preferences for content, appearance, and operational features to inform the design of a mobile phone app for reducing quantity and frequency of drinking in young adults engaged in harmful drinking (18-30 year olds). Phase 1 included a review of user reviews of available mobile phone apps that support a reduction in alcohol consumption. Apps were identified on iTunes and Google Play and were categorized into alcohol reduction support, entertainment, blood alcohol content measurement (BAC), or other. eSBI apps with ≥18 user reviews were subject to a content analysis, which coded praise, criticism, and recommendations for app content, functionality, and esthetics. Phase 2 included four focus groups with young adults drinking at harmful levels and residing in South London to explore their views on existing eSBI apps and preferences for future content, functionality, and appearance. Detailed thematic analysis of the data was undertaken. In Phase 1, of the 1584 apps extracted, 201 were categorized as alcohol reduction, 154 as BAC calculators, 509 as entertainment, and 720 as other. We classified 32 apps as eSBI apps. Four apps had ≥18 user reviews: Change for Life Drinks Tracker, Drinksmeter, Drinkaware, and Alcohol Units Calculator. The highest proportion of content praises were for information and feedback provided in the apps (12/27, 44%), followed by praise for the monitoring features (5/27, 19%). Many (8/12, 67%) criticisms were for the drinking diary; all of these were related to difficulty entering drinks. Over half (18/32, 56%) of functionality criticisms were descriptions of software bugs, and over half of those (10/18, 56%) were for app crashing or freezing. Drinksmeter and Alcohol Units Calculator were the most highly praised apps overall (23/57 and 22/57; 39% of praise overall). In Phase 2, two main themes were identified. The meaningfulness theme reflected how young adults thought apps needed to be tailored to the interests and values of their age group, particularly emphasizing content and feedback around broader health and well-being factors such as exercise, diet, and image. The community theme suggested that young adults want to be able to engage with other app users, both in groups of friends and with online users for motivation and support. Targeted and relevant information and feedback, in addition to easy-to-use monitoring tools, were found to be important features of a mobile phone app to support a reduction in drinking. Future app development should consider tailoring all app aspects to the needs of young adults, considering broader well-being monitoring tools and online community functions.

Automotive HMI design and participatory user involvement: review and perspectives.

PubMed

François, Mathilde; Osiurak, François; Fort, Alexandra; Crave, Philippe; Navarro, Jordan

2017-04-01

Automotive human-machine interface (HMI) design is facing new challenges due to the technological advances of the last decades. The design process has to be adapted in order to address human factors and road safety challenges. It is now widely accepted that user involvement in the HMI design process is valuable. However, the current form of user involvement in industry remains at the stages of concept assessment and usability tests. Moreover, the literature in other fields (e.g. information systems) promotes a broader user involvement with participatory design (i.e. the user is fully involved in the development process). This article reviews the established benefits of participatory design and reveals perspectives for automotive HMI quality improvement in a cognitive ergonomic framework. Practitioner Summary: Automotive HMI quality determines, in part, drivers' ability to perform primary driving tasks while using in-vehicle devices. User involvement in the design process is a key point to contribute to HMI quality. This article reports the potential benefits of a broad involvement from drivers to meet automotive HMI design challenges.

What we call what we do affects how we do it: a new nomenclature for simulation research in medical education.

PubMed

Haji, Faizal A; Hoppe, Daniel J; Morin, Marie-Paule; Giannoulakis, Konstantine; Koh, Jansen; Rojas, David; Cheung, Jeffrey J H

2014-05-01

Rapid technological advances and concern for patient safety have increased the focus on simulation as a pedagogical tool for educating health care providers. To date, simulation research scholarship has focused on two areas; evaluating instructional designs of simulation programs, and the integration of simulation into a broader educational context. However, these two categories of research currently exist under a single label-Simulation-Based Medical Education. In this paper we argue that introducing a more refined nomenclature within which to frame simulation research is necessary for researchers, to appropriately design research studies and describe their findings, and for end-point users (such as program directors and educators), to more appropriately understand and utilize this evidence.

Health: IT leader or laggard? A comparative assessment of IT maturity.

PubMed

England, Ian; Stewart, Don

2003-01-01

The health industry has acquired a reputation as lagging in the use of IT. This reputation is usually based upon the relatively narrow measure of comparative IT expenditure, often examined as a proportion of total revenue. This study has been undertaken to assess health's use of IT using a broader frame of reference. The health industry was compared to the banking industry, on the basis that the banking industry is widely perceived as a leading IT user. The research confirmed that in these two 'knowledge' industries, health is slower to adopt IT with an apparent lower maturity level. This was the case across a range of best practice management, procedural and cultural topics as well as in the level of resources applied to IT.

Intelligent viewing control for robotic and automation systems

NASA Astrophysics Data System (ADS)

Schenker, Paul S.; Peters, Stephen F.; Paljug, Eric D.; Kim, Won S.

1994-10-01

We present a new system for supervisory automated control of multiple remote cameras. Our primary purpose in developing this system has been to provide capability for knowledge- based, `hands-off' viewing during execution of teleoperation/telerobotic tasks. The reported technology has broader applicability to remote surveillance, telescience observation, automated manufacturing workcells, etc. We refer to this new capability as `Intelligent Viewing Control (IVC),' distinguishing it from a simple programmed camera motion control. In the IVC system, camera viewing assignment, sequencing, positioning, panning, and parameter adjustment (zoom, focus, aperture, etc.) are invoked and interactively executed by real-time by a knowledge-based controller, drawing on a priori known task models and constraints, including operator preferences. This multi-camera control is integrated with a real-time, high-fidelity 3D graphics simulation, which is correctly calibrated in perspective to the actual cameras and their platform kinematics (translation/pan-tilt). Such merged graphics- with-video design allows the system user to preview and modify the planned (`choreographed') viewing sequences. Further, during actual task execution, the system operator has available both the resulting optimized video sequence, as well as supplementary graphics views from arbitrary perspectives. IVC, including operator-interactive designation of robot task actions, is presented to the user as a well-integrated video-graphic single screen user interface allowing easy access to all relevant telerobot communication/command/control resources. We describe and show pictorial results of a preliminary IVC system implementation for telerobotic servicing of a satellite.

Snapchat elicits more jealousy than Facebook: a comparison of Snapchat and Facebook use.

PubMed

Utz, Sonja; Muscanell, Nicole; Khalid, Cameran

2015-03-01

Recent news in the media has suggested that younger people are using popular social media such as Facebook less and are quickly adopting newer media, such as the self-destructing app Snapchat. Snapchat is unique in that it erases messages several seconds after they have been sent, affording its users a higher level of privacy. Yet, little research exists on Snapchat use in general, let alone its broader psychological implications. This article offers a preliminary comparison of Snapchat and Facebook use and psychological effects on romantic jealousy. General motives for using Snapchat and Facebook are examined, as well as the nature of the content that Snapchat users most frequently share. Further, because of the differences in privacy and persistence of information, potential psychological effects in the domain of romantic jealousy are also examined, which has been widely studied on Facebook in the last few years. Findings show that the main difference in motives were that Snapchat was used more for flirting and finding new love interests, whereas Facebook was still the main social networking site used for keeping in touch with friends. Further, when presenting users with a series of potentially jealousy provoking scenarios, Snapchat elicited higher levels of jealousy than did Facebook. These findings are explained based on an affordance approach.

Cultural carrying capacity: Organ donation advocacy, discursive framing, and social media engagement.

PubMed

Bail, Christopher A

2016-09-01

Social media sites such as Facebook have become a powerful tool for public health outreach because they enable advocacy organizations to influence the rapidly increasing number of people who frequent these forums. Yet the very open-ness of social media sites creates fierce competition for public attention. The vast majority of social media messages provoke little or no reaction because of the sheer volume of information that confronts the typical social media user each day. In this article, I present a theory of the "cultural carrying capacity" of social media messaging campaigns. I argue that advocacy organizations inspire more endorsements, comments, and shares by social media users if they diversify the discursive content of their messages. Yet too much diversification creates large, disconnected audiences that lack the sense of shared purpose necessary to sustain an online movement. To evaluate this theory, I created a Facebook application that collects social media posts produced by forty-two organ donation advocacy organizations over 1.5 years, as well as supplemental information about the organization, its audience, and the broader social context in which they interact. Time series models provide strong evidence for my theory net of demographic characteristics of social media users, the resources and tactics of each organization, and broader external factors. I conclude by discussing the implications of these findings for public health, cultural sociology, and the nascent field of computational social science. Copyright © 2016 Elsevier Ltd. All rights reserved.

Ontology-based vector space model and fuzzy query expansion to retrieve knowledge on medical computational problem solutions.

PubMed

Bratsas, Charalampos; Koutkias, Vassilis; Kaimakamis, Evangelos; Bamidis, Panagiotis; Maglaveras, Nicos

2007-01-01

Medical Computational Problem (MCP) solving is related to medical problems and their computerized algorithmic solutions. In this paper, an extension of an ontology-based model to fuzzy logic is presented, as a means to enhance the information retrieval (IR) procedure in semantic management of MCPs. We present herein the methodology followed for the fuzzy expansion of the ontology model, the fuzzy query expansion procedure, as well as an appropriate ontology-based Vector Space Model (VSM) that was constructed for efficient mapping of user-defined MCP search criteria and MCP acquired knowledge. The relevant fuzzy thesaurus is constructed by calculating the simultaneous occurrences of terms and the term-to-term similarities derived from the ontology that utilizes UMLS (Unified Medical Language System) concepts by using Concept Unique Identifiers (CUI), synonyms, semantic types, and broader-narrower relationships for fuzzy query expansion. The current approach constitutes a sophisticated advance for effective, semantics-based MCP-related IR.

Funding sources for Canadian biorepositories: the role of user fees and strategies to help fill the gap.

PubMed

Barnes, Rebecca O; Schacter, Brent; Kodeeswaran, Sugy; Watson, Peter H

2014-10-01

Biorepositories, the coordinating hubs for the collection and annotation of biospecimens, are under increasing financial pressure and are challenged to remain sustainable. To gain a better understanding of the current funding situation for Canadian biorepositories and the relative contributions they receive from different funding sources, the Canadian Tumour Repository Network (CTRNet) conducted two surveys. The first survey targeted CTRNet's six main nodes to ascertain the relative funding sources and levels of user fees. The second survey was targeted to a broader range of biorepositories (n=45) to ascertain business practices in application of user fees. The results show that >70% of Canadian biorepositories apply user fees and that the majority apply differential fees to different user groups (academic vs. industry, local vs. international). However, user fees typically comprise only 6% of overall operational budgets. We conclude that while strategies to drive up user fee levels need to be implemented, it is essential for the many stakeholders in the biomedical health research sector to consider this issue in order to ensure the ongoing availability of research biospecimens and data that are standardized, high-quality, and that are therefore capable of meeting research needs.

Characterizing Social Interaction in Tobacco-Oriented Social Networks: An Empirical Analysis.

PubMed

Liang, Yunji; Zheng, Xiaolong; Zeng, Daniel Dajun; Zhou, Xingshe; Leischow, Scott James; Chung, Wingyan

2015-06-19

Social media is becoming a new battlefield for tobacco "wars". Evaluating the current situation is very crucial for the advocacy of tobacco control in the age of social media. To reveal the impact of tobacco-related user-generated content, this paper characterizes user interaction and social influence utilizing social network analysis and information theoretic approaches. Our empirical studies demonstrate that the exploding pro-tobacco content has long-lasting effects with more active users and broader influence, and reveal the shortage of social media resources in global tobacco control. It is found that the user interaction in the pro-tobacco group is more active, and user-generated content for tobacco promotion is more successful in obtaining user attention. Furthermore, we construct three tobacco-related social networks and investigate the topological patterns of these tobacco-related social networks. We find that the size of the pro-tobacco network overwhelms the others, which suggests a huge number of users are exposed to the pro-tobacco content. These results indicate that the gap between tobacco promotion and tobacco control is widening and tobacco control may be losing ground to tobacco promotion in social media.

Characterizing Social Interaction in Tobacco-Oriented Social Networks: An Empirical Analysis

PubMed Central

Liang, Yunji; Zheng, Xiaolong; Zeng, Daniel Dajun; Zhou, Xingshe; Leischow, Scott James; Chung, Wingyan

2015-01-01

Social media is becoming a new battlefield for tobacco “wars”. Evaluating the current situation is very crucial for the advocacy of tobacco control in the age of social media. To reveal the impact of tobacco-related user-generated content, this paper characterizes user interaction and social influence utilizing social network analysis and information theoretic approaches. Our empirical studies demonstrate that the exploding pro-tobacco content has long-lasting effects with more active users and broader influence, and reveal the shortage of social media resources in global tobacco control. It is found that the user interaction in the pro-tobacco group is more active, and user-generated content for tobacco promotion is more successful in obtaining user attention. Furthermore, we construct three tobacco-related social networks and investigate the topological patterns of these tobacco-related social networks. We find that the size of the pro-tobacco network overwhelms the others, which suggests a huge number of users are exposed to the pro-tobacco content. These results indicate that the gap between tobacco promotion and tobacco control is widening and tobacco control may be losing ground to tobacco promotion in social media. PMID:26091553

Sexual and gender minority's social media user characteristics: Examining preferred health information.

PubMed

Park, Hyojung; Rodgers, Shelly; McElroy, Jane A; Everett, Kevin

2018-01-01

The authors examined the influence of social media involvement on health issues in sexual and gender minorities (SGMs). Demographic and technological characteristics of social media users and nonusers were identified, and the influence of social media involvement on these factors was assessed for its potential to influence health information needs and preferences. A survey of 2,274 SGM individuals revealed that age, sexual orientation, number of Internet access points, and use of smartphones predicted levels of social media involvement. Results suggest that a broader range of traditional and nontraditional communication channels is needed to meet a diversity of health information needs in SGMs.

Service user governors in mental health foundation trusts: accountability or business as usual?

PubMed

MacDonald, Dee; Barnes, Marian; Crawford, Mike; Omeni, Edward; Wilson, Aaron; Rose, Diana

2015-12-01

National Health Foundation Trusts present opportunities for individual mental health service users to be active in the governance of trusts. This is one of a range of mechanisms for patient and public involvement and one which promotes an individual rather than collective approach to involvement. Within the context of a broader study of the impact of service user involvement in mental health services, the objective of this article was to explore the experience of service user governors in foundation trusts and their capacity to hold boards to account. The Council of Governors in three foundation trusts were observed for a year. Focus groups with service user governors were undertaken in each trust. Service users had different expectations and understandings of the role and approached it in different ways. Key themes that emerged concerned: the role of a governor, conduct and content of meetings, agenda setting, relationships and representation. The experiences of mental health service user governors need to be understood within the complex environment of patient and public involvement in general and of mental health service user involvement in particular. The dislocation of the service user governor role from other forms of service user activity and involvement result in confusion about how notions of holding a trust to account and representation of other service users can be addressed within a boundaried institutional environment. © 2014 John Wiley & Sons Ltd.

Sharing Research Models: Using Software Engineering Practices for Facilitation

PubMed Central

Bryant, Stephanie P.; Solano, Eric; Cantor, Susanna; Cooley, Philip C.; Wagener, Diane K.

2011-01-01

Increasingly, researchers are turning to computational models to understand the interplay of important variables on systems’ behaviors. Although researchers may develop models that meet the needs of their investigation, application limitations—such as nonintuitive user interface features and data input specifications—may limit the sharing of these tools with other research groups. By removing these barriers, other research groups that perform related work can leverage these work products to expedite their own investigations. The use of software engineering practices can enable managed application production and shared research artifacts among multiple research groups by promoting consistent models, reducing redundant effort, encouraging rigorous peer review, and facilitating research collaborations that are supported by a common toolset. This report discusses three established software engineering practices— the iterative software development process, object-oriented methodology, and Unified Modeling Language—and the applicability of these practices to computational model development. Our efforts to modify the MIDAS TranStat application to make it more user-friendly are presented as an example of how computational models that are based on research and developed using software engineering practices can benefit a broader audience of researchers. PMID:21687780

The development of an EDSS: Lessons learned and implications for DSS research

USGS Publications Warehouse

El-Gayar, O.; Deokar, A.; Michels, L.; Fosnight, G.

2011-01-01

The Solar and Wind Energy Resource Assessment (SWERA) project is focused on providing renewable energy (RE) planning resources to the public. Examples include wind, solar, and hydro assessments. SWERA DSS consists of three major components. First, SWERA 'Product Archive' provides for a discovery DSS upon which users can find and access renewable energy data and supporting models. Second, the 'Renewable Resource EXplorer' (RREX) component serves as a web-based, GIS analysis tool for viewing RE resource data available through the SWERA Product Archive. Third, the SWERA web service provides computational access to the data available in the SWERA spatial database through a location based query, and is also utilized in the RREX component. We provide a discussion of various design decisions used in the construction of this EDSS, followed by project experiences and implications for EDSS and broader DSS research. ?? 2011 IEEE.

Commentary: Eight Ways to Prevent Cancer: a framework for effective prevention messages for the public

PubMed Central

Dart, Hank; Wolin, Kathleen Y.; Colditz, Graham A.

2013-01-01

Research over the past 40 years has convincingly shown that lifestyle factors play a huge role in cancer incidence and mortality. The public, though, can often discount the preventability of cancer. That health information on the Internet is a vast and often scientifically suspect commodity makes promoting important and sound cancer prevention messages to the pubic even more difficult. To help address these issues and improve the public’s knowledge of, and attitudes toward, cancer prevention, there need to be concerted efforts to create evidence-based, user-friendly information about behaviors that could greatly reduce overall cancer risk. Toward this end, we condensed the current scientific evidence on the topic into eight key behaviors. While not an end in themselves, “8 Ways to Stay Healthy and Prevent Cancer” forms an evidence-based and targeted framework that supports broader cancer prevention efforts. PMID:22367724

Designing for emotion (among other things)

PubMed Central

Gaver, William

2009-01-01

Using computational approaches to emotion in design appears problematic for a range of technical, cultural and aesthetic reasons. After introducing some of the reasons as to why I am sceptical of such approaches, I describe a prototype we built that tried to address some of these problems, using sensor-based inferencing to comment upon domestic ‘well-being’ in ways that encouraged users to take authority over the emotional judgements offered by the system. Unfortunately, over two iterations we concluded that the prototype we built was a failure. I discuss the possible reasons for this and conclude that many of the problems we found are relevant more generally for designs based on computational approaches to emotion. As an alternative, I advocate a broader view of interaction design in which open-ended designs serve as resources for individual appropriation, and suggest that emotional experiences become one of several outcomes of engaging with them. PMID:19884154

Innovation Funds for Higher Education: A Users' Guide for World Bank Funded Projects. Education Working Paper Series. Number 1

ERIC Educational Resources Information Center

Saint, William

2005-01-01

The Education Working Paper Series is produced by the Education Unit at the World Bank (HDNED). It provides an avenue for World Bank staff to publish and disseminate preliminary education findings to encourage discussion and exchange ideas within the World Bank and among the broader development community. This Guide seeks to help those who design…

User-centered design in clinical handover: exploring post-implementation outcomes for clinicians.

PubMed

Wong, Ming Chao; Cummings, Elizabeth; Turner, Paul

2013-01-01

This paper examines the outcomes for clinicians from their involvement in the development of an electronic clinical hand-over tool developed using principles of user-centered design. Conventional e-health post-implementation evaluations tend to emphasize technology-related (mostly positive) outcomes. More recently, unintended (mostly negative) consequences arising from the implementation of e-health technologies have also been reported. There remains limited focus on the post-implementation outcomes for users, particularly those directly involved in e-health design processes. This paper presents detailed analysis and insights into the outcomes experienced post-implementation by a cohort of junior clinicians involved in developing an electronic clinical handover tool in Tasmania, Australia. The qualitative methods used included observations, semi-structured interviews and analysis of clinical handover notes. Significantly, a number of unanticipated flow-on effects were identified that mitigated some of the challenges arising during the design and implementation of the tool. The paper concludes by highlighting the importance of identifying post-implementation user outcomes beyond conventional system adoption and use and also points to the need for more comprehensive evaluative frameworks to encapsulate these broader socio-technical user outcomes.

Integrating pro-environmental behavior with transportation network modeling: User and system level strategies, implementation, and evaluation

NASA Astrophysics Data System (ADS)

Aziz, H. M. Abdul

Personal transport is a leading contributor to fossil fuel consumption and greenhouse (GHG) emissions in the U.S. The U.S. Energy Information Administration (EIA) reports that light-duty vehicles (LDV) are responsible for 61% of all transportation related energy consumption in 2012, which is equivalent to 8.4 million barrels of oil (fossil fuel) per day. The carbon content in fossil fuels is the primary source of GHG emissions that links to the challenge associated with climate change. Evidently, it is high time to develop actionable and innovative strategies to reduce fuel consumption and GHG emissions from the road transportation networks. This dissertation integrates the broader goal of minimizing energy and emissions into the transportation planning process using novel systems modeling approaches. This research aims to find, investigate, and evaluate strategies that minimize carbon-based fuel consumption and emissions for a transportation network. We propose user and system level strategies that can influence travel decisions and can reinforce pro-environmental attitudes of road users. Further, we develop strategies that system operators can implement to optimize traffic operations with emissions minimization goal. To complete the framework we develop an integrated traffic-emissions (EPA-MOVES) simulation framework that can assess the effectiveness of the strategies with computational efficiency and reasonable accuracy. The dissertation begins with exploring the trade-off between emissions and travel time in context of daily travel decisions and its heterogeneous nature. Data are collected from a web-based survey and the trade-off values indicating the average additional travel minutes a person is willing to consider for reducing a lb. of GHG emissions are estimated from random parameter models. Results indicate that different trade-off values for male and female groups. Further, participants from high-income households are found to have higher trade-off values compared with other groups. Next, we propose personal mobility carbon allowance (PMCA) scheme to reduce emissions from personal travel. PMCA is a market-based scheme that allocates carbon credits to users at no cost based on the emissions reduction goal of the system. Users can spend carbon credits for travel and a market place exists where users can buy or sell credits. This dissertation addresses two primary dimensions: the change in travel behavior of the users and the impact at network level in terms of travel time and emissions when PMCA is implemented. To understand this process, a real-time experimental game tool is developed where players are asked to make travel decisions within the carbon budget set by PMCA and they are allowed to trade carbon credits in a market modeled as a double auction game. Random parameter models are estimated to examine the impact of PMCA on short-term travel decisions. Further, to assess the impact at system level, a multi-class dynamic user equilibrium model is formulated that captures the travel behavior under PMCA scheme. The equivalent variational inequality problem is solved using projection method. Results indicate that PMCA scheme is able to reduce GHG emissions from transportation networks. Individuals with high value of travel time (VOTT) are less sensitive to PMCA scheme in context of work trips. High and medium income users are more likely to have non-work trips with lower carbon cost (higher travel time) to save carbon credits for work trips. Next, we focus on the strategies from the perspectives of system operators in transportation networks. Learning based signal control schemes are developed that can reduce emissions from signalized urban networks. The algorithms are implemented and tested in VISSIM micro simulator. Finally, an integrated emissions-traffic simulator framework is outlined that can be used to evaluate the effectiveness of the strategies. The integrated framework uses MOVES2010b as the emissions simulator. To estimate the emissions efficiently we propose a hierarchical clustering technique with dynamic time warping similarity measures (HC-DTW) to find the link driving schedules for MOVES2010b. Test results using the data from a five-intersection corridor show that HC-DTW technique can significantly reduce emissions estimation time without compromising the accuracy. The benefits are found to be most significant when the level of congestion variation is high. In addition to finding novel strategies for reducing emissions from transportation networks, this dissertation has broader impacts on behavior based energy policy design and transportation network modeling research. The trade-off values can be a useful indicator to identify which policies are most effective to reinforce pro-environmental travel choices. For instance, the model can estimate the distribution of trade-off between emissions and travel time, and provide insights on the effectiveness of policies for New York City if we are able to collect data to construct a representative sample. The probability of route choice decisions vary across population groups and trip contexts. The probability as a function of travel and demographic attributes can be used as behavior rules for agents in an agent-based traffic simulation. Finally, the dynamic user equilibrium based network model provides a general framework for energy policies such carbon tax, tradable permit, and emissions credits system.

Virtual reality and robotics for stroke rehabilitation: where do we go from here?

PubMed

Wade, Eric; Winstein, Carolee J

2011-01-01

Promoting functional recovery after stroke requires collaborative and innovative approaches to neurorehabilitation research. Task-oriented training (TOT) approaches that include challenging, adaptable, and meaningful activities have led to successful outcomes in several large-scale multisite definitive trials. This, along with recent technological advances of virtual reality and robotics, provides a fertile environment for furthering clinical research in neurorehabilitation. Both virtual reality and robotics make use of multimodal sensory interfaces to affect human behavior. In the therapeutic setting, these systems can be used to quantitatively monitor, manipulate, and augment the users' interaction with their environment, with the goal of promoting functional recovery. This article describes recent advances in virtual reality and robotics and the synergy with best clinical practice. Additionally, we describe the promise shown for automated assessments and in-home activity-based interventions. Finally, we propose a broader approach to ensuring that technology-based assessment and intervention complement evidence-based practice and maintain a patient-centered perspective.

Data Recipes: Toward Creating How-To Knowledge Base for Earth Science Data

NASA Technical Reports Server (NTRS)

Shen, Suhung; Lynnes, Chris; Acker, James G.; Beaty, Tammy

2015-01-01

Both the diversity and volume of Earth science data from satellites and numerical models are growing dramatically, due to an increasing population of measured physical parameters, and also an increasing variety of spatial and temporal resolutions for many data products. To further complicate matters, Earth science data delivered to data archive centers are commonly found in different formats and structures. NASA data centers, managed by the Earth Observing System Data and Information System (EOSDIS), have developed a rich and diverse set of data services and tools with features intended to simplify finding, downloading, and working with these data. Although most data services and tools have user guides, many users still experience difficulties with accessing or reading data due to varying levels of familiarity with data services, tools, and or formats. The data recipe project at Goddard Earth Science Data and Information Services Center (GES DISC) was initiated in late 2012 for enhancing user support. A data recipe is a How-To online explanatory document, with step-by-step instructions and examples of accessing and working with real data (http:disc.sci.gsfc.nasa.govrecipes). The current suite of recipes has been found to be very helpful, especially to first-time-users of particular data services, tools, or data products. Online traffic to the data recipe pages is significant, even though the data recipe topics are still limited. An Earth Science Data System Working Group (ESDSWG) for data recipes was established in the spring of 2014, aimed to initiate an EOSDIS-wide campaign for leveraging the distributed knowledge within EOSDIS and its user communities regarding their respective services and tools. The ESDSWG data recipe group is working on an inventory and analysis of existing data recipes and tutorials, and will provide guidelines and recommendation for writing and grouping data recipes, and for cross linking recipes to data products. This presentation gives an overview of the data recipe activites at GES DISC and ESDSWG. We are seeking requirements and input from a broader data user community to establish a strong knowledge base for Earth science data research and application implementations.

An Information Architect's View of Earth Observations for Disaster Risk Management

NASA Astrophysics Data System (ADS)

Moe, K.; Evans, J. D.; Cappelaere, P. G.; Frye, S. W.; Mandl, D.; Dobbs, K. E.

2014-12-01

Satellite observations play a significant role in supporting disaster response and risk management, however data complexity is a barrier to broader use especially by the public. In December 2013 the Committee on Earth Observation Satellites Working Group on Information Systems and Services documented a high-level reference model for the use of Earth observation satellites and associated products to support disaster risk management within the Global Earth Observation System of Systems context. The enterprise architecture identified the important role of user access to all key functions supporting situational awareness and decision-making. This paper focuses on the need to develop actionable information products from these Earth observations to simplify the discovery, access and use of tailored products. To this end, our team has developed an Open GeoSocial API proof-of-concept for GEOSS. We envision public access to mobile apps available on smart phones using common browsers where users can set up a profile and specify a region of interest for monitoring events such as floods and landslides. Information about susceptibility and weather forecasts about flood risks can be accessed. Users can generate geo-located information and photos of local events, and these can be shared on social media. The information architecture can address usability challenges to transform sensor data into actionable information, based on the terminology of the emergency management community responsible for informing the public. This paper describes the approach to collecting relevant material from the disasters and risk management community to address the end user needs for information. The resulting information architecture addresses the structural design of the shared information in the disasters and risk management enterprise. Key challenges are organizing and labeling information to support both online user communities and machine-to-machine processing for automated product generation.

Altered visual perception in long-term ecstasy (MDMA) users.

PubMed

White, Claire; Brown, John; Edwards, Mark

2013-09-01

The present study investigated the long-term consequences of ecstasy use on visual processes thought to reflect serotonergic functions in the occipital lobe. Evidence indicates that the main psychoactive ingredient in ecstasy (methylendioxymethamphetamine) causes long-term changes to the serotonin system in human users. Previous research has found that amphetamine-abstinent ecstasy users have disrupted visual processing in the occipital lobe which relies on serotonin, with researchers concluding that ecstasy broadens orientation tuning bandwidths. However, other processes may have accounted for these results. The aim of the present research was to determine if amphetamine-abstinent ecstasy users have changes in occipital lobe functioning, as revealed by two studies: a masking study that directly measured the width of orientation tuning bandwidths and a contour integration task that measured the strength of long-range connections in the visual cortex of drug users compared to controls. Participants were compared on the width of orientation tuning bandwidths (26 controls, 12 ecstasy users, 10 ecstasy + amphetamine users) and the strength of long-range connections (38 controls, 15 ecstasy user, 12 ecstasy + amphetamine users) in the occipital lobe. Amphetamine-abstinent ecstasy users had significantly broader orientation tuning bandwidths than controls and significantly lower contour detection thresholds (CDTs), indicating worse performance on the task, than both controls and ecstasy + amphetamine users. These results extend on previous research, which is consistent with the proposal that ecstasy may damage the serotonin system, resulting in behavioral changes on tests of visual perception processes which are thought to reflect serotonergic functions in the occipital lobe.

Using SPSS syntax: a beginner's guide Jacqueline Collier Using SPSS syntax: a beginner's guide Sage Pages: 216 £24.99 9781412922180 1412922186 [Formula: see text].

PubMed

2011-01-21

As someone who is comfortable with analysing data in SAS using coding language, it is perplexing that I run from the use of syntax in SPSS. But, my apprehension has subsided with the Collier's guide. Syntax command can automate processes, increase reproducibility and give the user broader access to features otherwise unavailable in SPSS.

Mobile capture of remote points of interest using line of sight modelling

NASA Astrophysics Data System (ADS)

Meek, Sam; Priestnall, Gary; Sharples, Mike; Goulding, James

2013-03-01

Recording points of interest using GPS whilst working in the field is an established technique in geographical fieldwork, where the user's current position is used as the spatial reference to be captured; this is known as geo-tagging. We outline the development and evaluation of a smartphone application called Zapp that enables geo-tagging of any distant point on the visible landscape. The ability of users to log or retrieve information relating to what they can see, rather than where they are standing, allows them to record observations of points in the broader landscape scene, or to access descriptions of landscape features from any viewpoint. The application uses the compass orientation and tilt of the phone to provide data for a line of sight algorithm that intersects with a Digital Surface Model stored on the mobile device. We describe the development process and design decisions for Zapp present the results of a controlled study of the accuracy of the application, and report on the use of Zapp for a student field exercise. The studies indicate the feasibility of the approach, but also how the appropriate use of such techniques will be constrained by current levels of precision in mobile sensor technology. The broader implications for interactive query of the distant landscape and for remote data logging are discussed.

Development and Application of Ontologies in Support of Earth and Space Science Education

NASA Astrophysics Data System (ADS)

Fox, S. P.; Manduca, C. A.; Iverson, E.

2007-12-01

Through its work in supporting improved science education the Science Education Resource Center (SERC) has developed and applied a set of Earth and Space Science vocabularies. These controlled vocabularies play a central role in supporting user exploration of our educational materials. The set of over 50 vocabularies run the gamut from small vocabularies with a narrowly targeted use, to broader vocabularies that span multiple disciplines and are applied across multiple projects and collections. Typical specialized vocabularies cover disciplinary themes such as tectonic setting (with terms such as mid-ocean ridge, passive margin, and craton) as well as interdisciplinary work such as geology and human health (with terms such as radionuclides and airborne transport processes). To support project-specific customization of vocabularies while retaining the benefits of cross-project reuse our systems allow for dynamic mapping of terms among multiple vocabularies based on semantic equivalencies. The end result is a weaving of related vocabularies into an ontological network that is exposed as specific vocabularies that employ the natural language of the collections and communities that use them. Our process for vocabulary development is community driven and reflects our experiences in aligning terminology with disciplinary-specific expectations. These experiences include rectifying language differences across disciplines in building a Geoscience Quantitative Skills vocabulary through work with both the Mathematics and Geoscience communities, as well as the iterative development of a vocabulary spanning Earth and Space science through the aggregation of smaller vocabularies, each developed by scientists for use within their own discipline. The vocabularies are exposed as key navigational features in over 100 faceted search interfaces within the web sites of a dozen Earth and Space Science Education projects. Within these faceted search interfaces the terms in the vocabularies act as guideposts and browsing links for the users. Only terms relevant to the current collection, or search return, are exposed to the users giving them an immediate sense of the scope and focus of the collection. In using vocabularies to drive these sorts of discovery processes it is critical that vocabularies not only have clear semantics so they can be applied consistently, but also have appropriate evocative meaning for the users of the search interface. It is this immediate evocative meaning, rather than the precisely defined semantics that will end up driving user search behavior and in the end determine the efficacy of the vocabulary as an applied tool. We will outline our experiences in developing and applying these vocabularies within the context of geoscience education and explore how the broader themes that emerge can inform the development and use of ontologies throughout Earth and space science.

Emotional Feedback and the Viral Spread of Social Media Messages About Autism Spectrum Disorders

PubMed Central

2016-01-01

Objective. To determine whether exchanges of emotional language between health advocacy organizations and social media users predict the spread of posts about autism spectrum disorders (ASDs). Methods. I created a Facebook application that tracked views of ASD advocacy organizations' posts between July 19, 2011, and December 18, 2012. I evaluated the association between exchanges of emotional language and viral views of posts, controlling for additional characteristics of posts, the organizations that produced them, the social media users who viewed them, and the broader social environment. Results. Exchanges of emotional language between advocacy organizations and social media users are strongly associated with viral views of posts. Conclusions. Social media outreach may be more successful if organizations invite emotional dialogue instead of simply conveying information about ASDs. Yet exchanges of angry language may contribute to the viral spread of misinformation, such as the rumor that vaccines cause ASDs. PMID:27196641

Emotional Feedback and the Viral Spread of Social Media Messages About Autism Spectrum Disorders.

PubMed

Bail, Christopher A

2016-07-01

To determine whether exchanges of emotional language between health advocacy organizations and social media users predict the spread of posts about autism spectrum disorders (ASDs). I created a Facebook application that tracked views of ASD advocacy organizations' posts between July 19, 2011, and December 18, 2012. I evaluated the association between exchanges of emotional language and viral views of posts, controlling for additional characteristics of posts, the organizations that produced them, the social media users who viewed them, and the broader social environment. Exchanges of emotional language between advocacy organizations and social media users are strongly associated with viral views of posts. Social media outreach may be more successful if organizations invite emotional dialogue instead of simply conveying information about ASDs. Yet exchanges of angry language may contribute to the viral spread of misinformation, such as the rumor that vaccines cause ASDs.

Protected Repository for the Defense of Infrastructure Against Cyber Threats (PREDICT) Dataset Development and Hosting

DTIC Science & Technology

2018-04-01

Creation, curation and hosting of datasets for cybersecurity researchers; • Serving as a “host of convenience” for datasets from PREDICT and IMPACT non...assumptions and preferences, as cybersecurity investigators and proxies for the broader current and potential user communities. No attempt was made to...understand what would have been of use, i.e., cybersecurity researcher needs were known more anecdotally than systematically.[1] We believe that

An Examination of Hispanic and General Population Perceptions of Organizational Environments

DTIC Science & Technology

1985-08-01

integrations concerning the relationship of cultural differences and social behavior (Technical Report No. 2), a method for the measurement of the...23 to the psychological. Dr. Jeffrey Schneider, then with ONR, asked a panel of five Navy users of social science findings to review these 41 findings...Hispanic culture be placed into a broader framework of cultural differences in social behavior? 6. What are the implications of our findings for the Navy

USGS QA Plan: Certification of digital airborne mapping products

USGS Publications Warehouse

Christopherson, J.

2007-01-01

To facilitate acceptance of new digital technologies in aerial imaging and mapping, the US Geological Survey (USGS) and its partners have launched a Quality Assurance (QA) Plan for Digital Aerial Imagery. This should provide a foundation for the quality of digital aerial imagery and products. It introduces broader considerations regarding processes employed by aerial flyers in collecting, processing and delivering data, and provides training and information for US producers and users alike.

Computer aided manual validation of mass spectrometry-based proteomic data.

PubMed

Curran, Timothy G; Bryson, Bryan D; Reigelhaupt, Michael; Johnson, Hannah; White, Forest M

2013-06-15

Advances in mass spectrometry-based proteomic technologies have increased the speed of analysis and the depth provided by a single analysis. Computational tools to evaluate the accuracy of peptide identifications from these high-throughput analyses have not kept pace with technological advances; currently the most common quality evaluation methods are based on statistical analysis of the likelihood of false positive identifications in large-scale data sets. While helpful, these calculations do not consider the accuracy of each identification, thus creating a precarious situation for biologists relying on the data to inform experimental design. Manual validation is the gold standard approach to confirm accuracy of database identifications, but is extremely time-intensive. To palliate the increasing time required to manually validate large proteomic datasets, we provide computer aided manual validation software (CAMV) to expedite the process. Relevant spectra are collected, catalogued, and pre-labeled, allowing users to efficiently judge the quality of each identification and summarize applicable quantitative information. CAMV significantly reduces the burden associated with manual validation and will hopefully encourage broader adoption of manual validation in mass spectrometry-based proteomics. Copyright © 2013 Elsevier Inc. All rights reserved.

Combining natural language processing and network analysis to examine how advocacy organizations stimulate conversation on social media.

PubMed

Bail, Christopher Andrew

2016-10-18

Social media sites are rapidly becoming one of the most important forums for public deliberation about advocacy issues. However, social scientists have not explained why some advocacy organizations produce social media messages that inspire far-ranging conversation among social media users, whereas the vast majority of them receive little or no attention. I argue that advocacy organizations are more likely to inspire comments from new social media audiences if they create "cultural bridges," or produce messages that combine conversational themes within an advocacy field that are seldom discussed together. I use natural language processing, network analysis, and a social media application to analyze how cultural bridges shaped public discourse about autism spectrum disorders on Facebook over the course of 1.5 years, controlling for various characteristics of advocacy organizations, their social media audiences, and the broader social context in which they interact. I show that organizations that create substantial cultural bridges provoke 2.52 times more comments about their messages from new social media users than those that do not, controlling for these factors. This study thus offers a theory of cultural messaging and public deliberation and computational techniques for text analysis and application-based survey research.

Active Exploration of Large 3D Model Repositories.

PubMed

Gao, Lin; Cao, Yan-Pei; Lai, Yu-Kun; Huang, Hao-Zhi; Kobbelt, Leif; Hu, Shi-Min

2015-12-01

With broader availability of large-scale 3D model repositories, the need for efficient and effective exploration becomes more and more urgent. Existing model retrieval techniques do not scale well with the size of the database since often a large number of very similar objects are returned for a query, and the possibilities to refine the search are quite limited. We propose an interactive approach where the user feeds an active learning procedure by labeling either entire models or parts of them as "like" or "dislike" such that the system can automatically update an active set of recommended models. To provide an intuitive user interface, candidate models are presented based on their estimated relevance for the current query. From the methodological point of view, our main contribution is to exploit not only the similarity between a query and the database models but also the similarities among the database models themselves. We achieve this by an offline pre-processing stage, where global and local shape descriptors are computed for each model and a sparse distance metric is derived that can be evaluated efficiently even for very large databases. We demonstrate the effectiveness of our method by interactively exploring a repository containing over 100 K models.

Towards high-throughput automated targeted femtosecond laser-based transfection of adherent cells

NASA Astrophysics Data System (ADS)

Antkowiak, Maciej; Torres-Mapa, Maria Leilani; Gunn-Moore, Frank; Dholakia, Kishan

2011-03-01

Femtosecond laser induced cell membrane poration has proven to be an attractive alternative to the classical methods of drug and gene delivery. It is a selective, sterile, non-contact technique that offers a highly localized operation, low toxicity and consistent performance. However, its broader application still requires the development of robust, high-throughput and user-friendly systems. We present a system capable of unassisted enhanced targeted optoinjection and phototransfection of adherent mammalian cells with a femtosecond laser. We demonstrate the advantages of a dynamic diffractive optical element, namely a spatial light modulator (SLM) for precise three dimensional positioning of the beam. It enables the implementation of a "point-and-shoot" system in which using the software interface a user simply points at the cell and a predefined sequence of precisely positioned doses can be applied. We show that irradiation in three axial positions alleviates the problem of exact beam positioning on the cell membrane and doubles the number of viably optoinjected cells when compared with a single dose. The presented system enables untargeted raster scan irradiation which provides transfection of adherent cells at the throughput of 1 cell per second.

The role of anthropometry in designing for sustainability.

PubMed

Nadadur, Gopal; Parkinson, Matthew B

2013-01-01

An understanding of human factors and ergonomics facilitates the design of artefacts, tasks and environments that fulfil their users' physical and cognitive requirements. Research in these fields furthers the goal of efficiently accommodating the desired percentage of user populations through enhanced awareness and modelling of human variability. Design for sustainability (DfS) allows for these concepts to be leveraged in the broader context of designing to minimise negative impacts on the environment. This paper focuses on anthropometry and proposes three ways in which its consideration is relevant to DfS: reducing raw material consumption, increasing usage lifetimes and ethical human resource considerations. This is demonstrated through the application of anthropometry synthesis, virtual fitting, and sizing and adjustability allocation methods in the design of an industrial workstation seat for use in five distinct global populations. This work highlights the importance of and opportunities for using ergonomic design principles in DfS efforts. This research demonstrates the relevance of some anthropometry-based ergonomics concepts to the field of design for sustainability. A global design case study leverages human variability considerations in furthering three sustainable design goals: reducing raw material consumption, increasing usage lifetimes and incorporating ethical human resource considerations in design.

Anti-human immunodeficiency virus-1 antibody titers in injection drug users compared to sexually infected individuals.

PubMed

Bongertz, Vera; Ouverney, Elaine Priscilla; Teixeira, Sylvia L M; Silva-de-Jesus, Carlos; Hacker, Mariana A; Morgado, Mariza G; Bastos, Francisco I

2003-03-01

Sera from infected injection drug users (IDU) have shown to have antibodies against synthetic human immunodeficiency virus-1 (HIV-1) envelope peptides more frequently. In this study, reactivity of 48 IDU plasma were compared to 60 plasmas obtained from sexually infected individuals (S). The overall reactivity of plasma from IDU compared to S was higher, and the reactivity titers were much higher for IDU plasma than S. IDU plasma also showed a broader antibody response. The higher reactivity titers were observed mainly for the gp41 immunodominant epitope and V3 peptides corresponding to the consensus sequences of HIV-1 subtypes/variants prevalent in Brazil (B, F, C) indicating the specificity in the higher immune response of IDU.

Detection of triazole deicing additives in soil samples from airports with low, mid, and large volume aircraft deicing activities.

PubMed

McNeill, K S; Cancilla, D A

2009-03-01

Soil samples from three USA airports representing low, mid, and large volume users of aircraft deicing fluids (ADAFs) were analyzed by LC/MS/MS for the presence of triazoles, a class of corrosion inhibitors historically used in ADAFs. Triazoles, specifically the 4-methyl-1H-benzotriazole and the 5-methyl-1H-benzotriazole, were detected in a majority of samples and ranged from 2.35 to 424.19 microg/kg. Previous studies have focused primarily on ground and surface water impacts of larger volume ADAF users. The detection of triazoles in soils at low volume ADAF use airports suggests that deicing activities may have a broader environmental impact than previously considered.

Expanding the Use of Time-Based Metering: Multi-Center Traffic Management Advisor

NASA Technical Reports Server (NTRS)

Landry, Steven J.; Farley, Todd; Hoang, Ty

2005-01-01

Time-based metering is an efficient air traffic management alternative to the more common practice of distance-based metering (or "miles-in-trail spacing"). Despite having demonstrated significant operational benefit to airspace users and service providers, time-based metering is used in the United States for arrivals to just nine airports and is not used at all for non-arrival traffic flows. The Multi-Center Traffic Management Advisor promises to bring time-based metering into the mainstream of air traffic management techniques. Not constrained to operate solely on arrival traffic, Multi-Center Traffic Management Advisor is flexible enough to work in highly congested or heavily partitioned airspace for any and all traffic flows in a region. This broader and more general application of time-based metering is expected to bring the operational benefits of time-based metering to a much wider pool of beneficiaries than is possible with existing technology. It also promises to facilitate more collaborative traffic management on a regional basis. This paper focuses on the operational concept of the Multi-Center Traffic Management Advisor, touching also on its system architecture, field test results, and prospects for near-term deployment to the United States National Airspace System.

Editorial: Journal article reporting standards.

PubMed

Kazak, Anne E

2018-01-01

In this editorial, the author notes that this issue of American Psychologist features a pair of important articles related to newly updated standards for reporting research in psychology in scientific journals, covering both quantitative (Appelbaum et al., 2018) and qualitative (Levitt et al., 2018) research. The increasing breadth and complexity of research, and the importance of communicating it effectively, requires user-friendly resources that can be applied widely to scientific studies. These two articles are intended to serve that purpose, and to encourage thoroughness and accuracy in research reporting, for psychologists and other scientists in broader academic communities. The articles, known as the Journal Article Reporting Standards (JARS) reports, are based on the work of a task force appointed by the American Psychological Association (APA) Publications and Communications Board in 2015. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Milliarcsecond Astronomy with the CHARA Array

NASA Astrophysics Data System (ADS)

Schaefer, Gail; ten Brummelaar, Theo; Gies, Douglas; Jones, Jeremy; Farrington, Christopher

2018-01-01

The Center for High Angular Resolution Astronomy offers 50 nights per year of open access time at the CHARA Array. The Array consists of six telescopes linked together as an interferometer, providing sub-milliarcsecond resolution in the optical and near-infrared. The Array enables a variety of scientific studies, including measuring stellar angular diameters, imaging stellar shapes and surface features, mapping the orbits of close binary companions, and resolving circumstellar environments. The open access time is part of an NSF/MSIP funded program to open the CHARA Array to the broader astronomical community. As part of the program, we will build a searchable database for the CHARA data archive and run a series of one-day community workshops at different locations across the country to expand the user base for stellar interferometry and encourage new scientific investigations with the CHARA Array.

Risky cannabis use is associated with alexithymia, frontal lobe dysfunction, and impulsivity in young adult cannabis users.

PubMed

Lyvers, Michael; Jamieson, Reuben; Thorberg, Fred Arne

2013-01-01

Risky or problematic alcohol use by young adults has been found to be associated with factors such as alexithymia, frontal lobe dysfunction, reward sensitivity, and impulsivity. One interpretation is that these factors reflect inherent traits that predispose to risky substance use in general, a notion examined in the present study. Alexithymia, everyday frontal lobe functioning, sensitivity to reward and punishment, and impulsivity were examined in 138 young adult cannabis users who were divided into Low Risk (n = 99) and Risky (n = 39) users according to their Cannabis Use Disorder Identification Test (CUDIT) scores. Risky cannabis use was significantly positively associated with alexithymia, multiple signs of frontal lobe dysfunction in everyday life, and impulsivity. A broader pattern of dysfunction was indicated for risky cannabis use than for risky alcohol use in this sample. Findings are interpreted as likely reflecting not only inherent traits that predispose to risky substance use in general, but also perhaps residual effects of recent heavy cannabis use in the Risky user group. Longitudinal research is needed to disentangle these competing possibilities.

User-Centered Design of a Tablet Waiting Room Tool for Complex Patients to Prioritize Discussion Topics for Primary Care Visits.

PubMed

Lyles, Courtney R; Altschuler, Andrea; Chawla, Neetu; Kowalski, Christine; McQuillan, Deanna; Bayliss, Elizabeth; Heisler, Michele; Grant, Richard W

2016-09-14

Complex patients with multiple chronic conditions often face significant challenges communicating and coordinating with their primary care physicians. These challenges are exacerbated by the limited time allotted to primary care visits. Our aim was to employ a user-centered design process to create a tablet tool for use by patients for visit discussion prioritization. We employed user-centered design methods to create a tablet-based waiting room tool that enables complex patients to identify and set discussion topic priorities for their primary care visit. In an iterative design process, we completed one-on-one interviews with 40 patients and their 17 primary care providers, followed by three design sessions with a 12-patient group. We audiorecorded and transcribed all discussions and categorized major themes. In addition, we met with 15 key health communication, education, and technology leaders within our health system to further review the design and plan for broader implementation of the tool. In this paper, we present the significant changes made to the tablet tool at each phase of this design work. Patient feedback emphasized the need to make the tablet tool accessible for patients who lacked technical proficiency and to reduce the quantity and complexity of text presentation. Both patients and their providers identified specific content choices based on their personal experiences (eg, the ability to raise private or sensitive concerns) and recommended targeting new patients. Stakeholder groups provided essential input on the need to augment text with video and to create different versions of the videos to match sex and race/ethnicity of the actors with patients. User-centered design in collaboration with patients, providers, and key health stakeholders led to marked evolution in the initial content, layout, and target audience for a tablet waiting room tool intended to assist complex patients with setting visit discussion priorities.

384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids.

PubMed

Hsiao, Amy Y; Tung, Yi-Chung; Qu, Xianggui; Patel, Lalit R; Pienta, Kenneth J; Takayama, Shuichi

2012-05-01

We previously reported the development of a simple, user-friendly, and versatile 384 hanging drop array plate for 3D spheroid culture and the importance of utilizing 3D cellular models in anti-cancer drug sensitivity testing. The 384 hanging drop array plate allows for high-throughput capabilities and offers significant improvements over existing 3D spheroid culture methods. To allow for practical 3D cell-based high-throughput screening and enable broader use of the plate, we characterize the robustness of the 384 hanging drop array plate in terms of assay performance and demonstrate the versatility of the plate. We find that the 384 hanging drop array plate performance is robust in fluorescence- and colorimetric-based assays through Z-factor calculations. Finally, we demonstrate different plate capabilities and applications, including: spheroid transfer and retrieval for Janus spheroid formation, sequential addition of cells for concentric layer patterning of different cell types, and culture of a wide variety of cell types. Copyright © 2011 Wiley Periodicals, Inc.

384 Hanging Drop Arrays Give Excellent Z-factors and Allow Versatile Formation of Co-culture Spheroids

PubMed Central

Hsiao, Amy Y.; Tung, Yi-Chung; Qu, Xianggui; Patel, Lalit R.; Pienta, Kenneth J.; Takayama, Shuichi

2012-01-01

We previously reported the development of a simple, user-friendly, and versatile 384 hanging drop array plate for 3D spheroid culture and the importance of utilizing 3D cellular models in anti-cancer drug sensitivity testing. The 384 hanging drop array plate allows for high-throughput capabilities and offers significant improvements over existing 3D spheroid culture methods. To allow for practical 3D cell-based high-throughput screening and enable broader use of the plate, we characterize the robustness of the 384 hanging drop array plate in terms of assay performance and demonstrate the versatility of the plate. We find that the 384 hanging drop array plate performance is robust in fluorescence- and colorimetric-based assays through z-factor calculations. Finally, we demonstrate different plate capabilities and applications, including: spheroid transfer and retrieval for Janus spheroid formation, sequential addition of cells for concentric layer patterning of different cell types, and culture of a wide variety of cell types. PMID:22161651

Models and Simulations as a Service: Exploring the Use of Galaxy for Delivering Computational Models

PubMed Central

Walker, Mark A.; Madduri, Ravi; Rodriguez, Alex; Greenstein, Joseph L.; Winslow, Raimond L.

2016-01-01

We describe the ways in which Galaxy, a web-based reproducible research platform, can be used for web-based sharing of complex computational models. Galaxy allows users to seamlessly customize and run simulations on cloud computing resources, a concept we refer to as Models and Simulations as a Service (MaSS). To illustrate this application of Galaxy, we have developed a tool suite for simulating a high spatial-resolution model of the cardiac Ca2+ spark that requires supercomputing resources for execution. We also present tools for simulating models encoded in the SBML and CellML model description languages, thus demonstrating how Galaxy’s reproducible research features can be leveraged by existing technologies. Finally, we demonstrate how the Galaxy workflow editor can be used to compose integrative models from constituent submodules. This work represents an important novel approach, to our knowledge, to making computational simulations more accessible to the broader scientific community. PMID:26958881

QuakeSim 2.0

NASA Technical Reports Server (NTRS)

Donnellan, Andrea; Parker, Jay W.; Lyzenga, Gregory A.; Granat, Robert A.; Norton, Charles D.; Rundle, John B.; Pierce, Marlon E.; Fox, Geoffrey C.; McLeod, Dennis; Ludwig, Lisa Grant

2012-01-01

QuakeSim 2.0 improves understanding of earthquake processes by providing modeling tools and integrating model applications and various heterogeneous data sources within a Web services environment. QuakeSim is a multisource, synergistic, data-intensive environment for modeling the behavior of earthquake faults individually, and as part of complex interacting systems. Remotely sensed geodetic data products may be explored, compared with faults and landscape features, mined by pattern analysis applications, and integrated with models and pattern analysis applications in a rich Web-based and visualization environment. Integration of heterogeneous data products with pattern informatics tools enables efficient development of models. Federated database components and visualization tools allow rapid exploration of large datasets, while pattern informatics enables identification of subtle, but important, features in large data sets. QuakeSim is valuable for earthquake investigations and modeling in its current state, and also serves as a prototype and nucleus for broader systems under development. The framework provides access to physics-based simulation tools that model the earthquake cycle and related crustal deformation. Spaceborne GPS and Inter ferometric Synthetic Aperture (InSAR) data provide information on near-term crustal deformation, while paleoseismic geologic data provide longerterm information on earthquake fault processes. These data sources are integrated into QuakeSim's QuakeTables database system, and are accessible by users or various model applications. UAVSAR repeat pass interferometry data products are added to the QuakeTables database, and are available through a browseable map interface or Representational State Transfer (REST) interfaces. Model applications can retrieve data from Quake Tables, or from third-party GPS velocity data services; alternatively, users can manually input parameters into the models. Pattern analysis of GPS and seismicity data has proved useful for mid-term forecasting of earthquakes, and for detecting subtle changes in crustal deformation. The GPS time series analysis has also proved useful as a data-quality tool, enabling the discovery of station anomalies and data processing and distribution errors. Improved visualization tools enable more efficient data exploration and understanding. Tools provide flexibility to science users for exploring data in new ways through download links, but also facilitate standard, intuitive, and routine uses for science users and end users such as emergency responders.

Commercial Research and Development: Power to Explore, Opportunities from Discovery

NASA Technical Reports Server (NTRS)

Casas, Joseph C.; Nall, Mark; Powers, C. Blake; Henderson, Robin N. (Technical Monitor)

2002-01-01

The technical and economic goals of commercial use of space are laudable, and are addressed as a high priority by almost every national space program and most major aerospace companies the world over. Yet, the focus of most organizational agendas and discussions tends to focus on one or two very narrow enabling aspects of this potentially large technological and economic opportunity. While government sponsored commercial launch activities and private space platforms are an integral part of efforts to leverage the commercial use of space, these activities are possibly one of the smallest parts of creating, a viable and sustainable market for the commercial use of space. Most of the current programs usually do not appropriately address some of the critical issues of the current, already interested, potential space user communities. Current programs place the focus of the majority of the user requirements on the vehicle payload weight and mass performance considerations as the primary payload economical factor in providing a commercial market with a stimulating price for gaining access to the space environment. The larger user challenges of transformation from Earth-based research and development approaches to space environment approaches are not addressed early enough in programs to impact the new business considerations of potential users. Currently, space-based research and development user activities require a large user investment in time, in development of new areas of support expertise, in development of new systems, in risk of schedule to completion, and in long term capital positioning. The larger opportunities for stimulating a strong market driven interest in commercial use of space that could result from the development of vehicle payload "leap ahead technologies" for users are being missed, and there is a real risk of limiting the potentially broader market base to support a more technologically advanced and economically lucrative outcome. A major driving force for strengthening the commercial space activities is not only the technological advances in launch vehicle, or newer satellites, but the myriad of enabling payloads technologies that could, as a goal, result in an almost transparent facilitation to regular CD a, -n access to space and microgravity environments by the future users from the existing Earth-based research and development organizations market segments. Rather than focusing only on developing high lift performance launch vehicles and then developing payloads to fit them, the real focus from a business model perspective should to be on the customer payloads requirements, and on designing launch vehicles and platforms systems for a space transportation and facility infrastructure to support all aspects of the business model for the user market. To harness the full potential of space commercialization, new efforts need to be made to comprehensively examine all the critical business model areas for commercial research, development, and manufacturing in space so as to identify specific products and efforts; to determine how such operations must be both similar to and different from current Earth-based activities; to evaluate the enabling technological devices, processes and efforts so that like efforts can be addressed in a synergistic fashion for maximum user cost effectiveness; to delineate the services that are both needed and can be provided by such activities; and to use this information to drive design and development of space commercialization efforts and policy.

Connecting proteins with drug-like compounds: Open source drug discovery workflows with BindingDB and KNIME

PubMed Central

Berthold, Michael R.; Hedrick, Michael P.; Gilson, Michael K.

2015-01-01

Today’s large, public databases of protein–small molecule interaction data are creating important new opportunities for data mining and integration. At the same time, new graphical user interface-based workflow tools offer facile alternatives to custom scripting for informatics and data analysis. Here, we illustrate how the large protein-ligand database BindingDB may be incorporated into KNIME workflows as a step toward the integration of pharmacological data with broader biomolecular analyses. Thus, we describe a collection of KNIME workflows that access BindingDB data via RESTful webservices and, for more intensive queries, via a local distillation of the full BindingDB dataset. We focus in particular on the KNIME implementation of knowledge-based tools to generate informed hypotheses regarding protein targets of bioactive compounds, based on notions of chemical similarity. A number of variants of this basic approach are tested for seven existing drugs with relatively ill-defined therapeutic targets, leading to replication of some previously confirmed results and discovery of new, high-quality hits. Implications for future development are discussed. Database URL: www.bindingdb.org PMID:26384374

How could health information exchange better meet the needs of care practitioners?

PubMed

Kierkegaard, P; Kaushal, R; Vest, J R

2014-01-01

Health information exchange (HIE) has the potential to improve the quality of healthcare by enabling providers with better access to patient information from multiple sources at the point of care. However, HIE efforts have historically been difficult to establish in the US and the failure rates of organizations created to foster HIE have been high. We sought to better understand how RHIO-based HIE systems were used in practice and the challenges care practitioners face using them. The objective of our study were to so investigate how HIE can better meet the needs of care practitioners. We performed a multiple-case study using qualitative methods in three communities in New York State. We conducted interviews onsite and by telephone with HIE users and non-users and observed the workflows of healthcare professionals at multiple healthcare organizations participating in a local HIE effort in New York State. The empirical data analysis suggests that challenges still remain in increasing provider usage, optimizing HIE implementations and connecting HIE systems across geographic regions. Important determinants of system usage and perceived value includes users experienced level of available information and the fit of use for physician workflows. Challenges still remain in increasing provider adoption, optimizing HIE implementations, and demonstrating value. The inability to find information reduced usage of HIE. Healthcare organizations, HIE facilitating organizations, and states can help support HIE adoption by ensuring patient information is accessible to providers through increasing patient consents, fostering broader participation, and by ensuring systems are usable.

Becoming a medical marijuana user.

PubMed

Lankenau, Stephen E; Kioumarsi, Avat; Reed, Megan; McNeeley, Miles; Iverson, Ellen; Wong, Carolyn F

2018-02-01

Since marijuana became legal for medical use in California in 1996, reasons for medical use among medical marijuana patients (MMP) have become increasingly well described in qualitative studies. However, few studies have detailed how the use of marijuana for medical purposes fits into the broader career trajectories of either becoming a marijuana user or becoming a MMP, including the social influences on medical use. Young adult MMP (N=40) aged 18 to 26 years old were recruited in Los Angeles, CA in 2014-15 and administered a semi-structured interview that included questions focusing on marijuana use practices before and after becoming MMP. MMP were categorized into three trajectory groups: primarily medical users (n=30); primarily non-medical users (n=3); and medical users who transitioned to non-medical users (n=7). Most medical users discovered medicinal effects from marijuana in the context of non-medical use as adolescents prior to becoming MMP. Becoming a mature MMP followed interactions with dispensary staff or further self-exploration of medical uses and often involved a social process that helped confirm the legitimacy of medical use and identity as a medical user. In some cases, MMP transitioned back to non-medical users as health conditions improved or remained primarily non-medical users even after becoming MMP for reasons unrelated to health, e.g., protection against arrest. Becoming a medical marijuana user was an important career trajectory that was influenced by early discoveries of effective medicinal use, interaction with proponents of medical use at dispensaries, experiences with new kinds of medical use, and the demands of particular health condition requiring more or less treatment with marijuana. Copyright © 2017 Elsevier B.V. All rights reserved.

VA OpenNotes: exploring the experiences of early patient adopters with access to clinical notes.

PubMed

Nazi, Kim M; Turvey, Carolyn L; Klein, Dawn M; Hogan, Timothy P; Woods, Susan S

2015-03-01

To explore the experience of early patient adopters who accessed their clinical notes online using the Blue Button feature of the My HealtheVet portal. A web-based survey of VA patient portal users from June 22 to September 15, 2013. 33.5% of respondents knew that clinical notes could be viewed, and nearly one in four (23.5%) said that they had viewed their notes at least once. The majority of VA Notes users agreed that accessing their notes will help them to do a better job of taking medications as prescribed (80.1%) and be better prepared for clinic visits (88.6%). Nine out of 10 users agreed that use of visit notes will help them understand their conditions better (91.8%), and better remember the plan for their care (91.9%). In contrast, 87% disagreed that VA Notes will make them worry more, and 88.4% disagreed that access to VA Notes will be more confusing than helpful. Users who had either contacted their provider or healthcare team (11.9%) or planned to (13.5%) primarily wanted to learn more about a health issue, medication, or test results (53.7%). Initial assessment of the patient experience within the first 9 months of availability provides evidence that patients both value and benefit from online access to clinical notes. These findings are congruent with OpenNotes study findings on a broader scale. Additional outreach and education is needed to enhance patient awareness. Healthcare professionals should author notes keeping in mind the opportunity patient access presents for enhanced communication. © The Author 2014. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

A modified operational sequence methodology for zoo exhibit design and renovation: conceptualizing animals, staff, and visitors as interdependent coworkers.

PubMed

Kelling, Nicholas J; Gaalema, Diann E; Kelling, Angela S

2014-01-01

Human factors analyses have been used to improve efficiency and safety in various work environments. Although generally limited to humans, the universality of these analyses allows for their formal application to a much broader domain. This paper outlines a model for the use of human factors to enhance zoo exhibits and optimize spaces for all user groups; zoo animals, zoo visitors, and zoo staff members. Zoo exhibits are multi-faceted and each user group has a distinct set of requirements that can clash or complement each other. Careful analysis and a reframing of the three groups as interdependent coworkers can enhance safety, efficiency, and experience for all user groups. This paper details a general creation and specific examples of the use of the modified human factors tools of function allocation, operational sequence diagram and needs assessment. These tools allow for adaptability and ease of understanding in the design or renovation of exhibits. © 2014 Wiley Periodicals, Inc.

Changing drug users' risk environments: peer health advocates as multi-level community change agents.

PubMed

Weeks, Margaret R; Convey, Mark; Dickson-Gomez, Julia; Li, Jianghong; Radda, Kim; Martinez, Maria; Robles, Eduardo

2009-06-01

Peer delivered, social oriented HIV prevention intervention designs are increasingly popular for addressing broader contexts of health risk beyond a focus on individual factors. Such interventions have the potential to affect multiple social levels of risk and change, including at the individual, network, and community levels, and reflect social ecological principles of interaction across social levels over time. The iterative and feedback dynamic generated by this multi-level effect increases the likelihood for sustained health improvement initiated by those trained to deliver the peer intervention. The Risk Avoidance Partnership (RAP), conducted with heroin and cocaine/crack users in Hartford, Connecticut, exemplified this intervention design and illustrated the multi-level effect on drug users' risk and harm reduction at the individual level, the social network level, and the larger community level. Implications of the RAP program for designing effective prevention programs and for analyzing long-term change to reduce HIV transmission among high-risk groups are discussed from this ecological and multi-level intervention perspective.

DNA Sequencing Technologies within the Chemical and Biological Defense Enterprise: How to Position the Department of Defense to Maximize the Use of These Emerging Technologies - JUPITR

DTIC Science & Technology

2015-07-01

sharing, the Pathosphere.org open-system architecture is now deployed and available on the Amazon cloud . The site has over 100 users from...SUPPLEMENTARY NOTES 14. ABSTRACT: To generate accurate and actionable disease data that can be integrated into the broader Department of Defense...PREFACE The work described in this report was authorized under the Joint United States Forces Korea Portal and Integrated Threat Recognition

Using a Theory of Change to Guide Grant Monitoring and Grantmaking.

PubMed

Glasgow, LaShawn; Adams, Elizabeth; Joshi, Sandhya; Curry, Laurel; Schmitt, Carol L; Rogers, Todd; Willett, Jeffrey; Van Hersh, Deanna

Charitable foundations play a significant role in advancing public health, funding billions of dollars in health grants each year. Evaluation is an important accountability tool for foundations and helps ensure that philanthropic investments contribute to the broader public health evidence base. While commitment to evaluation has increased among foundations over the past few decades, effective use of evaluation findings remains challenging. To facilitate use of evaluation findings among philanthropic organizations, evaluators can incorporate the foundation's theory of change-an illustration of the presumed causal pathways between a program's activities and its intended outcomes-into user-friendly products that summarize evaluation findings and recommendations. Using examples from the evaluation of the Kansas Health Foundation's Healthy Living Focus Area, we present a mapping technique that can be applied to assess and graphically depict alignment between program theory and program reality, refine the theory of change, and inform grantmaking.

Temporal abstraction-based clinical phenotyping with Eureka!

PubMed

Post, Andrew R; Kurc, Tahsin; Willard, Richie; Rathod, Himanshu; Mansour, Michel; Pai, Akshatha Kalsanka; Torian, William M; Agravat, Sanjay; Sturm, Suzanne; Saltz, Joel H

2013-01-01

Temporal abstraction, a method for specifying and detecting temporal patterns in clinical databases, is very expressive and performs well, but it is difficult for clinical investigators and data analysts to understand. Such patterns are critical in phenotyping patients using their medical records in research and quality improvement. We have previously developed the Analytic Information Warehouse (AIW), which computes such phenotypes using temporal abstraction but requires software engineers to use. We have extended the AIW's web user interface, Eureka! Clinical Analytics, to support specifying phenotypes using an alternative model that we developed with clinical stakeholders. The software converts phenotypes from this model to that of temporal abstraction prior to data processing. The model can represent all phenotypes in a quality improvement project and a growing set of phenotypes in a multi-site research study. Phenotyping that is accessible to investigators and IT personnel may enable its broader adoption.

Forecasting the Economic Impact of Future Space Station Operations

NASA Technical Reports Server (NTRS)

Summer, R. A.; Smolensky, S. M.; Muir, A. H.

1967-01-01

Recent manned and unmanned Earth-orbital operations have suggested great promise of improved knowledge and of substantial economic and associated benefits to be derived from services offered by a space station. Proposed application areas include agriculture, forestry, hydrology, public health, oceanography, natural disaster warning, and search/rescue operations. The need for reliable estimates of economic and related Earth-oriented benefits to be realized from Earth-orbital operations is discussed and recent work in this area is reviewed. Emphasis is given to those services based on remote sensing. Requirements for a uniform, comprehensive and flexible methodology are discussed. A brief review of the suggested methodology is presented. This methodology will be exercised through five case studies which were chosen from a gross inventory of almost 400 user candidates. The relationship of case study results to benefits in broader application areas is discussed, Some management implications of possible future program implementation are included.

Wide-field depth-sectioning fluorescence microscopy using projector-generated patterned illumination

NASA Astrophysics Data System (ADS)

Delica, Serafin; Mar Blanca, Carlo

2007-10-01

We present a simple and cost-effective wide-field, depth-sectioning, fluorescence microscope utilizing a commercial multimedia projector to generate excitation patterns on the sample. Highly resolved optical sections of fluorescent pollen grains at 1.9 μm axial resolution are constructed using the structured illumination technique. This requires grid excitation patterns to be scanned across the sample, which is straightforwardly implemented by creating slideshows of gratings at different phases, projecting them onto the sample, and synchronizing camera acquisition with slide transition. In addition to rapid dynamic pattern generation, the projector provides high illumination power and spectral excitation selectivity. We exploit these properties by imaging mouse neural cells in cultures multistained with Alexa 488 and Cy3. The spectral and structural neural information is effectively resolved in three dimensions. The flexibility and commercial availability of this light source is envisioned to open multidimensional imaging to a broader user base.

User guidelines and best practices for CASL VUQ analysis using Dakota.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, Brian M.; Swiler, Laura Painton; Hooper, Russell

2014-03-01

Sandia's Dakota software (available at http://dakota.sandia.gov) supports science and engineering transformation through advanced exploration of simulations. Specifically it manages and analyzes ensembles of simulations to provide broader and deeper perspective for analysts and decision makers. This enables them to enhance understanding of risk, improve products, and assess simulation credibility. This manual offers Consortium for Advanced Simulation of Light Water Reactors (LWRs) (CASL) partners a guide to conducting Dakota-based VUQ studies for CASL problems. It motivates various classes of Dakota methods and includes examples of their use on representative application problems. On reading, a CASL analyst should understand why and howmore » to apply Dakota to a simulation problem. This SAND report constitutes the product of CASL milestone L3:VUQ.V&V.P8.01 and is also being released as a CASL unlimited release report with number CASL-U-2014-0038-000.« less

Turning the Ship: The Transformation of DESY, 1993-2009

NASA Astrophysics Data System (ADS)

Heinze, Thomas; Hallonsten, Olof; Heinecke, Steffi

2017-12-01

This article chronicles the most recent history of the Deutsches Elektronen-Synchrotron (DESY) located in Hamburg, Germany, with particular emphasis on how this national laboratory founded for accelerator-based particle physics shifted its research program toward multi-disciplinary photon science. Synchrotron radiation became DESY's central experimental research program through a series of changes in its organizational, scientific, and infrastructural setup and the science policy context. Furthermore, the turn toward photon science is part of a broader transformation in the late twentieth century in which nuclear and particle physics, once the dominating fields in national and international science budgets, gave way to increasing investment in the materials sciences and life sciences. Synchrotron radiation research took a lead position on the experimental side of these growing fields and became a new form of big science, generously funded by governments and with user communities expanding across both academia and industry.

A user-friendly phytoremediation database: creating the searchable database, the users, and the broader implications.

PubMed

Famulari, Stevie; Witz, Kyla

2015-01-01

Designers, students, teachers, gardeners, farmers, landscape architects, architects, engineers, homeowners, and others have uses for the practice of phytoremediation. This research looks at the creation of a phytoremediation database which is designed for ease of use for a non-scientific user, as well as for students in an educational setting ( http://www.steviefamulari.net/phytoremediation ). During 2012, Environmental Artist & Professor of Landscape Architecture Stevie Famulari, with assistance from Kyla Witz, a landscape architecture student, created an online searchable database designed for high public accessibility. The database is a record of research of plant species that aid in the uptake of contaminants, including metals, organic materials, biodiesels & oils, and radionuclides. The database consists of multiple interconnected indexes categorized into common and scientific plant name, contaminant name, and contaminant type. It includes photographs, hardiness zones, specific plant qualities, full citations to the original research, and other relevant information intended to aid those designing with phytoremediation search for potential plants which may be used to address their site's need. The objective of the terminology section is to remove uncertainty for more inexperienced users, and to clarify terms for a more user-friendly experience. Implications of the work, including education and ease of browsing, as well as use of the database in teaching, are discussed.

US Topo: topographic maps for the nation

USGS Publications Warehouse

Carswell, William J.

2013-01-01

US Topo is the next generation of topographic maps from the U.S. Geological Survey (USGS). Arranged in the familiar 7.5-minute quadrangle format, digital US Topo maps are designed to look and feel (and perform) like the traditional paper topographic maps for which the USGS is so well known. In contrast to paper-based maps, US Topo maps provide modern technical advantages that support faster, wider public distribution and enable basic, on-screen geographic analysis for all users. The US Topo quadrangle map has been redesigned so that map elements are visually distinguishable with the imagery turned on and off, while keeping the file size as small as possible. The US Topo map redesign includes improvements to various display factors, including symbol definitions (color, line thickness, line symbology, area fills), layer order, and annotation fonts. New features for 2013 include the following: a raster shaded relief layer, military boundaries, cemeteries and post offices, and a US Topo cartographic symbols legend as an attachment. US Topo quadrangle maps are available free on the Web. Each map quadrangle is constructed in GeoPDF® format using key layers of geographic data (orthoimagery, roads, geographic names, topographic contours, and hydrographic features) from The National Map databases. US Topo quadrangle maps can be printed from personal computers or plotters as complete, full-sized, maps or in customized sections, in a user-desired specific format. Paper copies of the maps can also be purchased from the USGS Store. Download links and a users guide are featured on the US Topo Web site. US Topo users can turn geographic data layers on and off as needed; they can zoom in and out to highlight specific features or see a broader area. File size for each digital 7.5-minute quadrangle, about 30 megabytes. Associated electronic tools for geographic analysis are available free for download. The US Topo provides the Nation with a topographic product that users can quickly incorporate into decisionmaking, operational or recreational activities.

Adoptive immunotherapy for cancer.

PubMed

Ruella, Marco; Kalos, Michael

2014-01-01

Recent clinical success has underscored the potential for immunotherapy based on the adoptive cell transfer (ACT) of engineered T lymphocytes to mediate dramatic, potent, and durable clinical responses. This success has led to the broader evaluation of engineered T-lymphocyte-based adoptive cell therapy to treat a broad range of malignancies. In this review, we summarize concepts, successes, and challenges for the broader development of this promising field, focusing principally on lessons gleaned from immunological principles and clinical thought. We present ACT in the context of integrating T-cell and tumor biology and the broader systemic immune response. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Necessary but not Sufficient - Closing the Gap Between Data Access and Use by a Broad User Community

NASA Astrophysics Data System (ADS)

Benedict, K. K.; Pennington, D. D.

2012-12-01

Earth science cyberinfrastructure developers like the team at the University of New Mexico Earth Data Analysis Center (EDAC) and University of Texas at El Paso Cyber-ShARE Center of Excellence work closely with researchers to document and transfer their research products (data and related materials) into systems that will allow for long-term access and reuse, both in the research domain within which they were generated but also for potential use outside that domain. While we have generally treated this problem as a technical one in which we develop robust systems that can reliably deliver interoperable data and visualization services to a wide variety of client applications and platforms we have not yet achieved the potential of ubiquitous use of our science data holdings outside of the community that developed them. A number of barriers must be overcome to realize the broader potential of these data: Discoverability - data must be discoverable through the tools and interfaces that are used by the broader community in addition to the specialized archives with which the source communities interact Understanding - data must be documented in ways that allow other potential users to understand the content, context, and potential use of data products Usability - data must be available in a variety of formats and packages that are easily integrated into the systems and processes that are already in use by the prospective end users Transferability - the rights and obligations of potential users must be clearly defined for data products (i.e. licensing terms) Planning - data management must be planned for from the beginning so that all of the above can be accomplished This paper presents some of the activities that EDAC and Cyber-ShARE have undertaken (in partnership with collaborators at KU, DataONE, New Mexico Department of Health, Pacific Northwest National Laboratory, and the New Mexico EPSCoR Program) in working to overcome these barriers to increased use of scientific data products in education and across research domains. EDAC focuses primarily on discoverability, usability, and transformability using current best practices while Cyber-ShARE's efforts are directed primarily toward emerging Semantic Web approaches for planning, discoverability, and understanding.

Knights, knaves, pawns and queens: attitudes to behaviour in postwar Britain

PubMed Central

Welshman, John

2007-01-01

The choice agenda is currently one of the most prominent in public policy. One of its main architects, Julian Le Grand, has used the metaphors of knights, knaves, pawns and queens to characterise changing attitudes to questions of motivation and behaviour among public servants and service users. He has said, for example, that, in the immediate postwar period, public servants were perceived as public‐spirited altruists (or knights), whereas service users were seen as passive (or pawns). It was only in the mid‐1980s that public servants came to be seen as essentially self‐interested (knaves) and service users came to be regarded as consumers (queens). However, this highly influential model has undergone remarkably little critical scrutiny to date. This article explores the debate over transmitted deprivation in the 1970s to provide a historically grounded piece of analysis to explore the accuracy and utility of these metaphors. It challenges Le Grand's arguments in three respects. Firstly, a concern with behaviour and agency went much broader than social security fraud. Secondly, the metaphor of pawns is inadequate for characterising attitudes towards the poor and service users. Finally, Le Grand's periodisation of the postwar era also has serious flaws. PMID:17234865

Using Social Media, Online Social Networks, and Internet Search as Platforms for Public Health Interventions: A Pilot Study.

PubMed

Huesch, Marco D; Galstyan, Aram; Ong, Michael K; Doctor, Jason N

2016-06-01

To pilot public health interventions at women potentially interested in maternity care via campaigns on social media (Twitter), social networks (Facebook), and online search engines (Google Search). Primary data from Twitter, Facebook, and Google Search on users of these platforms in Los Angeles between March and July 2014. Observational study measuring the responses of targeted users of Twitter, Facebook, and Google Search exposed to our sponsored messages soliciting them to start an engagement process by clicking through to a study website containing information on maternity care quality information for the Los Angeles market. Campaigns reached a little more than 140,000 consumers each day across the three platforms, with a little more than 400 engagements each day. Facebook and Google search had broader reach, better engagement rates, and lower costs than Twitter. Costs to reach 1,000 targeted users were approximately in the same range as less well-targeted radio and TV advertisements, while initial engagements-a user clicking through an advertisement-cost less than $1 each. Our results suggest that commercially available online advertising platforms in wide use by other industries could play a role in targeted public health interventions. © Health Research and Educational Trust.

Combining natural language processing and network analysis to examine how advocacy organizations stimulate conversation on social media

PubMed Central

Bail, Christopher Andrew

2016-01-01

Social media sites are rapidly becoming one of the most important forums for public deliberation about advocacy issues. However, social scientists have not explained why some advocacy organizations produce social media messages that inspire far-ranging conversation among social media users, whereas the vast majority of them receive little or no attention. I argue that advocacy organizations are more likely to inspire comments from new social media audiences if they create “cultural bridges,” or produce messages that combine conversational themes within an advocacy field that are seldom discussed together. I use natural language processing, network analysis, and a social media application to analyze how cultural bridges shaped public discourse about autism spectrum disorders on Facebook over the course of 1.5 years, controlling for various characteristics of advocacy organizations, their social media audiences, and the broader social context in which they interact. I show that organizations that create substantial cultural bridges provoke 2.52 times more comments about their messages from new social media users than those that do not, controlling for these factors. This study thus offers a theory of cultural messaging and public deliberation and computational techniques for text analysis and application-based survey research. PMID:27694580

Evaluating international development investments based on ecosystem services impact

NASA Astrophysics Data System (ADS)

Fremier, A. K.; Brauman, K. A.; Mulligan, M.; Chaplin-Kramer, R.; Gordon, L.; Luedeling, E.; Jones, S. K.; DeClerck, F.

2016-12-01

Engineered water-control structures to supply water for agriculture are frequently funded by international development to an effort to improve human wellbeing. Dams, reservoirs, and other forms of water control frequently have negative impacts on other water users; however, their sustainability in the face of climate change and evolving watershed processes have been called into question. Increasingly, planning for and evaluation of investments in water control require integration of these larger scale impacts and dependencies. Ecosystem service approaches can use local to regional scale knowledge to integrate a broader scope of project impacts by quantifying trade-offs in multiple services across proposed development interventions and future scenarios (economic, climate, demographic). Here, we illustrate the role an ecosystem service approach can play in investment decision making to evaluate the impact of small reservoirs on human wellbeing in the Upper Volta Basin of West Africa. Our project has four components: (1) design of a spatially explicit regional-level social-ecological characterization; (2) construction of future scenario analyses for rainfed and irrigated production system interventions; (3) co-design and co-development of benefit sharing mechanisms at the reservoir catchment level and enhancing institutional capacity to implement these mechanisms through training, professional development and targeting tools; and (4) intervention decision analysis to identify benefits, costs and risks associated with decision options. We illustrate how this approach highlights different outcomes than standard cost-benefit analysis focused narrowly on the single project. Anticipated outcomes are development of ecosystem services-based methods for more equitably and sustainably evaluating development interventions and identifying management approaches to water-impoundment structures that promote a range of ecosystem services to provide food security to a broader population.

Enhancing the Value of Sensor-based Observations by Capturing the Knowledge of How An Observation Came to Be

NASA Astrophysics Data System (ADS)

Fredericks, J.; Rueda-Velasquez, C. A.

2016-12-01

As we move from keeping data on our disks to sharing it with the world, often in real-time, we are obligated to also tell an unknown user about how our observations were made. Data that are shared must not only have ownership metadata, unit descriptions and content formatting information. The provider must also share information that is needed to assess the data as it relates to potential re-use. A user must be able to assess the limitations and capabilities of the sensor, as it is configured, to understand its value. For example, when an instrument is configured, it typically affects the data accuracy and operational limits of the sensor. An operator may sacrifice data accuracy to achieve a broader operational range and visa versa. If you are looking at newly discovered data, it is important to be able to find all of the information that relates to assessing the data quality for your particular application. Traditionally, metadata are captured by data managers who usually do not know how the data are collected. By the time data are distributed, this knowledge is often gone, buried within notebooks or hidden in documents that are not machine-harvestable and often not human-readable. In a recently funded NSF EarthCube Integrative Activity called X-DOMES (Cross-Domain Observational Metadata in EnviroSensing), mechanisms are underway to enable the capture of sensor and deployment metadata by sensor manufacturers and field operators. The support has enabled the development of a community ontology repository (COR) within the Earth Science Information Partnership (ESIP) community, fostering easy creation of resolvable terms for the broader community. This tool enables non-experts to easily develop W3C standards-based content, promoting the implementation of Semantic Web technologies for enhanced discovery of content and interoperability in workflows. The X-DOMES project is also developing a SensorML Viewer/Editor to provide an easy interface for sensor manufacturers and field operators to fully-describe sensor capabilities and configuration/deployment content - automatically generating it in machine-harvestable encodings that can be referenced by data managers and/or associated with the data through web-services, such as the OGC SWE Sensor Observation Service.

Standard development at the Human Variome Project.

PubMed

Smith, Timothy D; Vihinen, Mauno

2015-01-01

The Human Variome Project (HVP) is a world organization working towards facilitating the collection, curation, interpretation and free and open sharing of genetic variation information. A key component of HVP activities is the development of standards and guidelines. HVP Standards are systems, procedures and technologies that the HVP Consortium has determined must be used by HVP-affiliated data sharing infrastructure and should be used by the broader community. HVP guidelines are considered to be beneficial for HVP affiliated data sharing infrastructure and the broader community to adopt. The HVP also maintains a process for assessing systems, processes and tools that implement HVP Standards and Guidelines. Recommended System Status is an accreditation process designed to encourage the adoption of HVP Standards and Guidelines. Here, we describe the HVP standards development process and discuss the accepted standards, guidelines and recommended systems as well as those under acceptance. Certain HVP Standards and Guidelines are already widely adopted by the community and there are committed users for the others. © The Author(s) 2015. Published by Oxford University Press.

Standard development at the Human Variome Project

PubMed Central

Smith, Timothy D.; Vihinen, Mauno

2015-01-01

The Human Variome Project (HVP) is a world organization working towards facilitating the collection, curation, interpretation and free and open sharing of genetic variation information. A key component of HVP activities is the development of standards and guidelines. HVP Standards are systems, procedures and technologies that the HVP Consortium has determined must be used by HVP-affiliated data sharing infrastructure and should be used by the broader community. HVP guidelines are considered to be beneficial for HVP affiliated data sharing infrastructure and the broader community to adopt. The HVP also maintains a process for assessing systems, processes and tools that implement HVP Standards and Guidelines. Recommended System Status is an accreditation process designed to encourage the adoption of HVP Standards and Guidelines. Here, we describe the HVP standards development process and discuss the accepted standards, guidelines and recommended systems as well as those under acceptance. Certain HVP Standards and Guidelines are already widely adopted by the community and there are committed users for the others. PMID:25818894

Knowledge Translation: Moving Proteomics Science to Innovation in Society.

PubMed

Holmes, Christina; McDonald, Fiona; Jones, Mavis; Graham, Janice

2016-06-01

Proteomics is one of the pivotal next-generation biotechnologies in the current "postgenomics" era. Little is known about the ways in which innovative proteomics science is navigating the complex socio-political space between laboratory and society. It cannot be assumed that the trajectory between proteomics laboratory and society is linear and unidirectional. Concerned about public accountability and hopes for knowledge-based innovations, funding agencies and citizens increasingly expect that emerging science and technologies, such as proteomics, are effectively translated and disseminated as innovation in society. Here, we describe translation strategies promoted in the knowledge translation (KT) and science communication literatures and examine the use of these strategies within the field of proteomics. Drawing on data generated from qualitative interviews with proteomics scientists and ethnographic observation of international proteomics conferences over a 5-year period, we found that proteomics science incorporates a variety of KT strategies to reach knowledge users outside the field. To attain the full benefit of KT, however, proteomics scientists must challenge their own normative assumptions and approaches to innovation dissemination-beyond the current paradigm relying primarily on publication for one's scientific peers within one's field-and embrace the value of broader (interdisciplinary) KT strategies in promoting the uptake of their research. Notably, the Human Proteome Organization (HUPO) is paying increasing attention to a broader range of KT strategies, including targeted dissemination, integrated KT, and public outreach. We suggest that increasing the variety of KT strategies employed by proteomics scientists is timely and would serve well the omics system sciences community.

National Ignition Facility Laser System Performance

DOE PAGES

Spaeth, Mary L.; Manes, Kenneth R.; Bowers, M.; ...

2017-03-23

The National Ignition Facility (NIF) laser is the culmination of more than 40 years of work at Lawrence Livermore National Laboratory dedicated to the delivery of laser systems capable of driving experiments for the study of high-energy-density physics. Although NIF was designed to support a number of missions, it was clear from the beginning that its biggest challenge was to meet the requirements for pursuit of inertial confinement fusion. Meeting the Project Completion Criteria for NIF in 2009 and for the National Ignition Campaign (NIC) in 2012 included meeting the NIF Functional Requirements and Primary Criteria that were established formore » the project in 1994. Finally, during NIC and as NIF transitioned to a user facility, its goals were expanded to include requirements defined by the broader user community as well as by laser system designers and operators.« less

Information and communication technologies for approaching smokers: a descriptive study in primary healthcare.

PubMed

Puigdomènech, Elisa; Trujillo-Gómez, Jose-Manuel; Martín-Cantera, Carlos; Díaz-Gete, Laura; Manzano-Montero, Mónica; Sánchez-Fondevila, Jessica; Gonzalez-Fernandez, Yolanda; Garcia-Rueda, Beatriz; Briones-Carrió, Elena-Mercedes; Clemente-Jiménez, Ma-Lourdes; Castaño, Carmen; Birulés-Muntané, Joan

2015-02-13

Common interventions for smoking cessation are based on medical advice and pharmacological aid. Information and communication technologies may be helpful as interventions by themselves or as complementary tools to quit smoking. The objective of the study was to determine the use of information and communication technologies (ICTs) in the smoking population attended in primary care, and describe the major factors associated with its use. Descriptive observational study in 84 health centres in Cataluña, Aragon and Salamanca. We included by simple random sampling 1725 primary healthcare smokers (any amount of tobacco) aged 18-85. Through personal interview professionals collected Socio-demographic data and variables related with tobacco consumption and ICTs use were collected through face to face interviews Factors associated with the use of ICTs were analyzed by logistic regression. Users of at least one ICT were predominantly male, young (18-45 years), from most favoured social classes and of higher education. Compared with non-ICTs users, users declared lower consumption of tobacco, younger onset age, and lower nicotine dependence. The percentages of use of email, text messages and web pages were 65.3%, 74.0% and 71.5%, respectively. Factors associated with the use of ICTs were age, social class, educational level and nicotine dependence level. The factor most closely associated with the use of all three ICTs was age; mainly individuals aged 18-24. The use of ICTs to quit smoking is promising, with the technology of mobile phones having a broader potential. Younger and more educated subjects are good targets for ICTs interventions on smoking cessation.

Making Your Tools Useful to a Broader Audience

NASA Astrophysics Data System (ADS)

Lyness, M. D.; Broten, M. J.

2006-12-01

With the increasing growth of Web Services and SOAP the ability to connect and reuse computational and also visualization tools from all over the world via Web Interfaces that can be easily displayed in any current browser has provided the means to construct an ideal online research environment. The age-old question of usability is a major determining factor whether a particular tool would find great success in its community. An interface that can be understood purely by a user's intuition is desirable and more closely obtainable than ever before. Through the use of increasingly sophisticated web-oriented technologies including JavaScript, AJAX, and the DOM, web interfaces are able to harness the advantages of the Internet along with the functional capabilities of native applications such as menus, partial page changes, background processing, and visual effects to name a few. Also, with computers becoming a normal part of the educational process companies, such as Google and Microsoft, give us a synthetic intuition as a foundation for new designs. Understanding the way earth science researchers know how to use computers will allow the VLab portal (http://vlab.msi.umn.edu) and other projects to create interfaces that will get used. To provide detailed communication with the users of VLab's computational tools, projects like the Porky Portlet (http://www.gorerle.com/vlab-wiki/index.php?title=Porky_Portlet) spawned to empower users with a fully- detailed, interactive visual representation of progressing workflows. With the well-thought design of such tools and interfaces, researchers around the world will become accustomed to new highly engaging, visual web- based research environments.

How could Health Information Exchange Better Meet the Needs of Care Practitioners?

PubMed Central

Kaushal, R.; Vest, J.R.

2014-01-01

Summary Background Health information exchange (HIE) has the potential to improve the quality of healthcare by enabling providers with better access to patient information from multiple sources at the point of care. However, HIE efforts have historically been difficult to establish in the US and the failure rates of organizations created to foster HIE have been high. Objectives We sought to better understand how RHIO-based HIE systems were used in practice and the challenges care practitioners face using them. The objective of our study were to so investigate how HIE can better meet the needs of care practitioners. Methods We performed a multiple-case study using qualitative methods in three communities in New York State. We conducted interviews onsite and by telephone with HIE users and non-users and observed the workflows of healthcare professionals at multiple healthcare organizations participating in a local HIE effort in New York State. Results The empirical data analysis suggests that challenges still remain in increasing provider usage, optimizing HIE implementations and connecting HIE systems across geographic regions. Important determinants of system usage and perceived value includes users experienced level of available information and the fit of use for physician workflows. Conclusions Challenges still remain in increasing provider adoption, optimizing HIE implementations, and demonstrating value. The inability to find information reduced usage of HIE. Healthcare organizations, HIE facilitating organizations, and states can help support HIE adoption by ensuring patient information is accessible to providers through increasing patient consents, fostering broader participation, and by ensuring systems are usable. PMID:25589903

Sustaining Broader Impacts through Researcher-Teacher Collaboration (A Model Based on Award Abstract #1334935: Collaborative Research: Investigating the Ecological Importance of Iron Storage in Diatoms.)

NASA Astrophysics Data System (ADS)

Sutton, M.; Marchetti, A.

2016-02-01

Broader impacts have become a vital component of scientific research projects. A variety of outreach avenues are available to assist scientists in reaching larger audiences, however, the translation of cutting-edge scientific content and concepts can be challenging. Collaborating with educators is a viable option to assist researchers in fulfilling NSF's broader impact requirements. A broader impacts model based on collaborations between a teacher and 28 researchers from 14 institutions will demonstrate successful science outreach and engagement through interactions between teachers, researchers, students, and general audiences. Communication styles (i.e., blogs, social media) and outreach data incorporated by researchers and the teacher will be shared to illustrate the magnitude of the broader impacts achieved with this partnership. Inquiry-based investigations and activities developed to translate the science into the classroom will also be demonstrated, including the use of real scientific data collected during the research cruise. "Finding Microbe Needles in a Haystack of Oceans" provides an understanding of how remote sensing technology is used to locate specific ocean environments (e.g. High Nutrient Low Chlorophyll - HNLC) that support diverse microbial food webs. A board game ("Diatom Adventures©") designed to explore the physiology of microbial organisms and microscopic food webs will also be demonstrated. The tentative nature of science requires a constant vigil to stay abreast of the latest hypotheses and discoveries. Researcher/Teacher collaborations allow each professional to focus on his/her strengths while meeting broader impact requirements. These partnerships encourage lifelong learning as educators observe and work with scientists first-hand and then follow appropriate scope, sequence, and pedagogy to assist various audiences in understanding the innovative technologies being used to explore new scientific frontiers.

Social media and health information sharing among Australian Indigenous people.

PubMed

Hefler, Marita; Kerrigan, Vicki; Henryks, Joanna; Freeman, Becky; Thomas, David P

2018-04-17

Despite the enormous potential of social media for health promotion, there is an inadequate evidence base for how they can be used effectively to influence behaviour. In Australia, research suggests social media use is higher among Aboriginal and Torres Strait Islander people than the general Australian population; however, health promoters need a better understanding of who uses technologies, how and why. This qualitative study investigates what types of health content are being shared among Aboriginal and Torres Strait people through social media networks, as well as how people engage with, and are influenced by, health-related information in their offline life. We present six social media user typologies together with an overview of health content that generated significant interaction. Content ranged from typical health-related issues such as mental health, diet, alcohol, smoking and exercise, through to a range of broader social determinants of health. Social media-based health promotion approaches that build on the social capital generated by supportive online environments may be more likely to generate greater traction than confronting and emotion-inducing approaches used in mass media campaigns for some health topics.

Promoting scientific collaboration and research through integrated social networking capabilities within the OpenTopography Portal

NASA Astrophysics Data System (ADS)

Nandigam, V.; Crosby, C. J.; Baru, C.

2009-04-01

LiDAR (Light Distance And Ranging) topography data offer earth scientists the opportunity to study the earth's surface at very high resolutions. As a result, the popularity of these data is growing dramatically. However, the management, distribution, and analysis of community LiDAR data sets is a challenge due to their massive size (multi-billion point, mutli-terabyte). We have also found that many earth science users of these data sets lack the computing resources and expertise required to process these data. We have developed the OpenTopography Portal to democratize access to these large and computationally challenging data sets. The OpenTopography Portal uses cyberinfrastructure technology developed by the GEON project to provide access to LiDAR data in a variety of formats. LiDAR data products available range from simple Google Earth visualizations of LiDAR-derived hillshades to 1 km2 tiles of standard digital elevation model (DEM) products as well as LiDAR point cloud data and user generated custom-DEMs. We have found that the wide spectrum of LiDAR users have variable scientific applications, computing resources and technical experience and thus require a data system with multiple distribution mechanisms and platforms to serve a broader range of user communities. Because the volume of LiDAR topography data available is rapidly expanding, and data analysis techniques are evolving, there is a need for the user community to be able to communicate and interact to share knowledge and experiences. To address this need, the OpenTopography Portal enables social networking capabilities through a variety of collaboration tools, web 2.0 technologies and customized usage pattern tracking. Fundamentally, these tools offer users the ability to communicate, to access and share documents, participate in discussions, and to keep up to date on upcoming events and emerging technologies. The OpenTopography portal achieves the social networking capabilities by integrating various software technologies and platforms. These include the Expression Engine Content Management System (CMS) that comes with pre-packaged collaboration tools like blogs and wikis, the Gridsphere portal framework that contains the primary GEON LiDAR System portlet with user job monitoring capabilities and a java web based discussion forum (Jforums) application all seamlessly integrated under one portal. The OpenTopography Portal also provides integrated authentication mechanism between the various CMS collaboration tools and the core gridsphere based portlets. The integration of these various technologies allows for enhanced user interaction capabilities within the portal. By integrating popular collaboration tools like discussion forums and blogs we can promote conversation and openness among users. The ability to ask question and share expertise in forum discussions allows users to easily find information and interact with users facing similar challenges. The OpenTopography Blog enables our domain experts to post ideas, news items, commentary, and other resources in order to foster discussion and information sharing. The content management capabilities of the portal allow for easy updates to information in the form of publications, documents, and news articles. Access to the most current information fosters better decision-making. As has become the standard for web 2.0 technologies, the OpenTopography Portal is fully RSS enabled to allow users of the portal to keep track of news items, forum discussions, blog updates, and system outages. We are currently exploring how the information captured by user and job monitoring components of the Gridsphere based GEON LiDAR System can be harnessed to provide a recommender system that will help users to identify appropriate processing parameters and to locate related documents and data. By seamlessly integrating the various platforms and technologies under one single portal, we can take advantage of popular online collaboration tools that are either stand alone or software platform restricted. The availability of these collaboration tools along with the data will foster more community interaction and increase the strength and vibrancy of the LiDAR topography user community.

Users of the main smartphone operating systems (iOS, Android) differ only little in personality

PubMed Central

Stieger, Stefan; Reips, Ulf-Dietrich

2017-01-01

The increasingly widespread use of mobile phone applications (apps) as research tools and cost-effective means of vast data collection raises new methodological challenges. In recent years, it has become a common practice for scientists to design apps that run only on a single operating system, thereby excluding large numbers of users who use a different operating system. However, empirical evidence investigating any selection biases that might result thereof is scarce. Henceforth, we conducted two studies drawing from a large multi-national (Study 1; N = 1,081) and a German-speaking sample (Study 2; N = 2,438). As such Study 1 compared iOS and Android users across an array of key personality traits (i.e., well-being, self-esteem, willingness to take risks, optimism, pessimism, Dark Triad, and the Big Five). Focusing on Big Five personality traits in a broader scope, in addition to smartphone users, Study 2 also examined users of the main computer operating systems (i.e., Mac OS, Windows). In both studies, very few significant differences were found, all of which were of small or even tiny effect size mostly disappearing after sociodemographics had been controlled for. Taken together, minor differences in personality seem to exist, but they are of small to negligible effect size (ranging from OR = 0.919 to 1.344 (Study 1), ηp2 = .005 to .036 (Study 2), respectively) and may reflect differences in sociodemographic composition, rather than operating system of smartphone users. PMID:28467473

Users of the main smartphone operating systems (iOS, Android) differ only little in personality.

PubMed

Götz, Friedrich M; Stieger, Stefan; Reips, Ulf-Dietrich

2017-01-01

The increasingly widespread use of mobile phone applications (apps) as research tools and cost-effective means of vast data collection raises new methodological challenges. In recent years, it has become a common practice for scientists to design apps that run only on a single operating system, thereby excluding large numbers of users who use a different operating system. However, empirical evidence investigating any selection biases that might result thereof is scarce. Henceforth, we conducted two studies drawing from a large multi-national (Study 1; N = 1,081) and a German-speaking sample (Study 2; N = 2,438). As such Study 1 compared iOS and Android users across an array of key personality traits (i.e., well-being, self-esteem, willingness to take risks, optimism, pessimism, Dark Triad, and the Big Five). Focusing on Big Five personality traits in a broader scope, in addition to smartphone users, Study 2 also examined users of the main computer operating systems (i.e., Mac OS, Windows). In both studies, very few significant differences were found, all of which were of small or even tiny effect size mostly disappearing after sociodemographics had been controlled for. Taken together, minor differences in personality seem to exist, but they are of small to negligible effect size (ranging from OR = 0.919 to 1.344 (Study 1), ηp2 = .005 to .036 (Study 2), respectively) and may reflect differences in sociodemographic composition, rather than operating system of smartphone users.

Impacts of a Temporary Urban Pop-Up Park on Physical Activity and Other Individual- and Community-Level Outcomes.

PubMed

Salvo, Deborah; Banda, Jorge A; Sheats, Jylana L; Winter, Sandra J; Lopes Dos Santos, Daniela; King, Abby C

2017-08-01

Physical inactivity is a known risk factor for obesity and a number of chronic diseases. Modifying the physical features of neighborhoods to provide residents with equitable and convenient access to spaces for physical activity (PA) is a promising strategy for promoting PA. Public urban recreation spaces (e.g., parks) play an important role in promoting PA and are potentially an important neighborhood element for optimizing social capital and liveability in cities. Most studies examining the effects of park availability and use on PA have focused on traditional, permanent parks. The aims of this study were to (1) document patterns of park use and park-based PA at a temporary urban pop-up park implemented in the downtown business district of Los Altos, California during July-August 2013 and May-June 2014, (2) identify factors associated with park-based PA in 2014, and (3) examine the effects of the 2014 pop-up park on additional outcomes of potential benefit for park users and the Los Altos community at large. Park use remained high during most hours of the day in 2013 and 2014. Although the park attracted a multigenerational group of users, children and adolescents were most likely to engage in walking or more vigorous PA at the park. Park presence was significantly associated with potentially beneficial changes in time-allocation patterns among users, including a reduction in screen-time and an increase in overall park-time and time spent outdoors. Park implementation resulted in notable use among people who would otherwise not be spending time at a park (85% of surveyed users would not be spending time at any other park if the pop-up park was not there-2014 data analysis). Our results (significantly higher odds of spending time in downtown Los Altos due to park presence) suggest that urban pop-up parks may also have broader community benefits, such as attracting people to visit downtown business districts. Pending larger, confirmatory studies, our results suggest that temporary urban pop-up parks may contribute to solving the limited access to public physical activity recreation spaces many urban residents face.

Excessive internet use in European adolescents: what determines differences in severity?

PubMed

Blinka, Lukas; Škařupová, Kateřina; Ševčíková, Anna; Wölfling, Klaus; Müller, Kai W; Dreier, Michael

2015-02-01

This study investigated the differences between non-excessive, moderately excessive, and highly excessive internet use among adolescents. These differences were explored in terms of personal characteristics, psychological difficulties, environmental factors, and manner of internet use. A representative sample was investigated, consisting of 18,709 adolescents aged 11-16 and their parents, from 25 European countries. Excessive internet use was measured using a five item scale covering following factors: salience, conflict, tolerance, withdrawal symptoms, and relapse and reinstatement. The main data analysis utilised multinomial and binary logistic regression models. The vast majority of respondents reported no signs of excessive internet use. Moderately excessive users (4.4%) reported higher emotional and behavioural difficulties, but also more sophisticated digital skills and a broader range of online activities. The highly excessive users (1.4%) differed from the non-excessive and moderately excessive users in their preference for online games and in having more difficulties with self-control. Adolescents who struggle with attention and self-control and who are inclined toward online gaming may be especially vulnerable to the otherwise uncommon phenomenon of excessive internet use.

Land use and environmental assessment in the central Atlantic region

NASA Technical Reports Server (NTRS)

Alexander, R. H.; Fitzpatrick, K.; Lins, H. F., Jr.; Mcginty, H. K., III

1975-01-01

Data from high altitude aircraft, LANDSAT and Skylab were used in a comprehensive regional survey of land use and its associated environmental impact in the Central Atlantic Regional Ecological Test Site (CARETS). Each sensor system has advantages that were demonstrated by producing experimental land use maps and other data products, applying them to typical problems encountered in regional planning and environmental impact assessment, and presenting the results to prospective users for evaluation. An archival collection of imagery, maps, data summaries, and technical reports was assembled, constituting an environmental profile of the central Atlantic region. The investigation was organized into four closely-related modules, a land use information module, an environmental impact module, a user interaction and evaluation module, and a geographic information systems module. Results revealed a heterogeneous user community with diverse information needs, tending, however, definitely toward the higher-resolution sensor data and the larger-scale land use maps and related information products. Among project recommendations are greater efforts toward improving compatibility of federal, state, and local land use information programs, and greater efforts toward a broader exchange of imagery, computer tapes, and land use information derived therefrom.

Assessing Family Planning Service Quality And User Experiences In Social Franchising Programme - Case Studies From Two Rural Districts In Pakistan.

PubMed

Azmat, Syed Khurram; Ali, Moazzam; Hameed, Waqas; Awan, Muhammad Ali

2018-01-01

Studies have documented the impact of quality family planning services on improved contraceptive uptake and continuation, however, relatively little is known about their quality of service provision especially in the context of social franchising. This study examined the quality of clinical services and user experiences among two models in franchised service providers in rural Pakistan. This facility-based assessment was carried out during May-June 2015 at the 20 randomly selected social franchise providers from Chakwal and Faisalabad. In our case, a franchise health facility was a private clinic (mostly) run by a single provider, supported by an assistant. Within the selected health facilities, a total 39 user-provider interactions were observed and same users were interviewed separately. Most of the health facilities were in the private sector. Comparatively, service providers at Greenstar Social Marketing/Population Services International (GSM/PSI) model franchised facilities had higher number of rooms and staff employed, with more providers' ownership. Quality of service indices showed high scores for both Marie Stopes Society (MSS) and GSM/PSI franchised providers. MSS franchised providers demonstrated comparative edge in terms of clinical governance, better method mix and they were more user-focused, while PSI providers offered broader range of non-FP services. Quality of counselling services were similar among both models. Service providers performed well on all indicators of interpersonal care however overall low scores were noted in technical care. For both models, service providers attained an average score of 6.7 (out of the maximum value of 8) on waste disposal mechanism, supplies 12.5 (out of the maximum value of 15), user-centred facility 2.7 (out of the maximum value of 4), and clinical governance 6.5 (out of the maximum value of 11) and respecting clients' privacy. The exit interviews yielded high user satisfaction in both service models. The findings seem suggesting that the MSS and GSM/PSI service providers were maintaining high quality standards in provision of family planning information, services, and commodities but overall there was not much difference between the two models in terms of quality and satisfaction. The results demonstrate that service quality and client satisfaction are an important determinant of use of clinical contraceptive methods in Pakistan.

Online Video-Based Training in the Use of Hydrologic Models: A Case Example Using SWAT

NASA Astrophysics Data System (ADS)

Frankenberger, J.

2009-12-01

Hydrologic models are increasingly important tools in public decision-making. For example, watershed models are used to develop Total Maximum Daily Load (TMDL) plans, quantify pollutant loads, and estimate the effects of watershed restoration efforts funded by the public. One widely-used tool is the Soil and Water Assessment Tool (SWAT), which has been applied by state and federal agencies, consultants, and university researchers to assess sources of nonpoint source pollution and the effects of potential solutions, and used in testimony in at least one lawsuit. The SWAT model has the capability to evaluate the relative effects of different management scenarios on water quality, sediment, and agricultural chemical yield at the watershed scale. As with all models, the model user and the decisions that s/he makes in the modeling process are important determinants of model performance. The SWAT model has an open structure, leaving most decisions up to the model user, which was especially appropriate when the model was primarily used in research by highly-experienced modelers. However, as the model has become more widely applied in planning and assessment, by people who may have limited hydrology background and modeling knowledge, the possibility that users may be using the model inconsistently or even incorrectly becomes a concern. Consistent training can lead to a minimum standard of knowledge that model users are expected to have, and therefore to higher use of best practices in modeling efforts. In addition, widespread availability of training can lead to better decisions about when and where using the model is appropriate, and what level of data needs to be available for confidence in predictions. Currently, most training in model use takes place in occasional face-to-face workshops, courses offered at a few universities, and a short tutorial available in the manual. Many new users simply acquire the model and learn from the manual, other users, trial and error, and posing questions to the web-based group. Although excellent model documentation is available (http://www.brc.tamus.edu/swat/), the extent to which users conduct careful study to ensure that their understanding goes beyond the superficial level is unknown. Online video-on-demand technology provides a way for users to learn consistent content while saving travel resources, and allows for training to fit into people’s schedule. Online videos were created to teach the basics of setting up the model, acquiring input data, parameterizing, calibrating and evaluating model results, and analyzing outputs, as well as model science, uncertainty, and appropriate use. Feedback was sought from the SWAT modeling community to determine typical backgrounds of model users and how the video training fits into the available means of learning SWAT. Evaluation is being undertaken to assess results. The processes used in developing and evaluating the online SWAT training could be applied to other computer models for which use among broader groups of people is increasing or has the potential to grow.

Crossing the river: Developing a strategy to support understanding of uncertainty within probabilistic climate projections.

NASA Astrophysics Data System (ADS)

Walton, P.; Lamb, R.

2010-09-01

The UK Climate Impacts Programme (UKCIP) was established by government in 1997 to support the UK's engagement with becoming better adapted to a changing climate. As the lead organisation in the UK on climate change adaptation, UKCIP oversaw the development of the UK Climate Projections (UKCP09) which were launched in June 2009 providing, for the first time, probabilistic climate projections for the UK. As with previous generations of UKCIP climate scenarios, they were freely accessible and intended for a whole spectrum of users, from technical experts to a lay audience. . Prior to the launch of UKCP09 it was acknowledged that users would need support in understanding key concepts, such as the uncertainty inherent in the projections, to be able to use them appropriately. The user support strategy was therefore developed. It is founded on robust pedagogical principles and draws on the latest thinking on public understanding of science (PUS) that places the user at the centre of the communication process. The adopted approach first identifies profiles of the key users of the climate projections and the ways in which they would use and access the data. Based on these profiles it is possible to identify a range of mechanisms that allow the user to engage with understanding the projections in different ways and situations including lectures, workshops and online learning. Within this blended strategy an exercise was developed specifically to support users' understanding of the concept of uncertainty within the probabilistic climate projections. The ‘Crossing the River' exercise encourages the participants to actively consider the nature of information they are using, and how it could be applied in a specific decision. Reflection and discussion are key elements in supporting the users' understanding of the concept and allowing them to apply the principles in the exercise to their own context. Their reflection is facilitated through a range of mechanisms that provide social and personal spaces and is guided by the communicator. The exercise has been used successfully with a broad range of users (from government officers to environmental managers) in groups ranging from small community events to large corporate conferences. Feedback has shown that the majority of people who completed the exercise had a better understanding of the concept of uncertainty within the probabilistic climate projections as a result. We are now working to create an online version that can be freely accessed by users along with other resources that develop understanding of other key concepts associated with UKCP09 and the broader climate change adaptation agenda. This paper evaluates the development and application of the user support strategy and provides a practical illustration of how it can be used within a face-to-face group setting and also as an online resource.

dictyExpress: a web-based platform for sequence data management and analytics in Dictyostelium and beyond.

PubMed

Stajdohar, Miha; Rosengarten, Rafael D; Kokosar, Janez; Jeran, Luka; Blenkus, Domen; Shaulsky, Gad; Zupan, Blaz

2017-06-02

Dictyostelium discoideum, a soil-dwelling social amoeba, is a model for the study of numerous biological processes. Research in the field has benefited mightily from the adoption of next-generation sequencing for genomics and transcriptomics. Dictyostelium biologists now face the widespread challenges of analyzing and exploring high dimensional data sets to generate hypotheses and discovering novel insights. We present dictyExpress (2.0), a web application designed for exploratory analysis of gene expression data, as well as data from related experiments such as Chromatin Immunoprecipitation sequencing (ChIP-Seq). The application features visualization modules that include time course expression profiles, clustering, gene ontology enrichment analysis, differential expression analysis and comparison of experiments. All visualizations are interactive and interconnected, such that the selection of genes in one module propagates instantly to visualizations in other modules. dictyExpress currently stores the data from over 800 Dictyostelium experiments and is embedded within a general-purpose software framework for management of next-generation sequencing data. dictyExpress allows users to explore their data in a broader context by reciprocal linking with dictyBase-a repository of Dictyostelium genomic data. In addition, we introduce a companion application called GenBoard, an intuitive graphic user interface for data management and bioinformatics analysis. dictyExpress and GenBoard enable broad adoption of next generation sequencing based inquiries by the Dictyostelium research community. Labs without the means to undertake deep sequencing projects can mine the data available to the public. The entire information flow, from raw sequence data to hypothesis testing, can be accomplished in an efficient workspace. The software framework is generalizable and represents a useful approach for any research community. To encourage more wide usage, the backend is open-source, available for extension and further development by bioinformaticians and data scientists.

Using Noninvasive Wearable Computers to Recognize Human Emotions from Physiological Signals

NASA Astrophysics Data System (ADS)

Lisetti, Christine Lætitia; Nasoz, Fatma

2004-12-01

We discuss the strong relationship between affect and cognition and the importance of emotions in multimodal human computer interaction (HCI) and user modeling. We introduce the overall paradigm for our multimodal system that aims at recognizing its users' emotions and at responding to them accordingly depending upon the current context or application. We then describe the design of the emotion elicitation experiment we conducted by collecting, via wearable computers, physiological signals from the autonomic nervous system (galvanic skin response, heart rate, temperature) and mapping them to certain emotions (sadness, anger, fear, surprise, frustration, and amusement). We show the results of three different supervised learning algorithms that categorize these collected signals in terms of emotions, and generalize their learning to recognize emotions from new collections of signals. We finally discuss possible broader impact and potential applications of emotion recognition for multimodal intelligent systems.

Use of the Go-for-Green nutrition labeling system in military dining facilities is associated with lower fat intake.

PubMed

Arsenault, Joanne E; Singleton, Michelle C; Funderburk, LesLee K

2014-07-01

Point-of-purchase nutrition labeling is a potential tool to help consumers choose healthier foods. The objectives of our study were to survey soldiers on their use of the Go-for-Green nutrition labeling system in dining facilities and compare characteristics of users and nonusers. The study population consisted of 299 US Army active duty soldiers at two US Army installations. The frequency of use of food labels and characteristics were calculated and differences in characteristics of label users and nonusers were compared using χ(2) and regression analyses. Forty-seven percent of soldiers reported using nutrition labels to make food choices always or sometimes. Users were more likely to be following a special diet (P=0.04) and to take a multivitamin or protein supplement (P<0.001) than nonusers. Users consumed a mean of 32% of energy from fat vs 36% for nonusers (P<0.0001) after adjusting for reported use of special diets. Use of the Go-for-Green nutrition labeling system is encouraging and should be further investigated to determine whether the program is actually influencing dietary choices in broader military settings. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

Developing inclusive partnerships: user-defined outcomes, networking and knowledge--a case study.

PubMed

Beresford, Peter; Branfield, Fran

2006-09-01

Two major developments have been associated with the reorientation of United Kingdom health and social care policy and provision in recent years, placing a new emphasis on: quality and 'outcome' measures; and service user (and public and patient) involvement. These issues have become central to health and social care, representing expressions of the shift in political and ideological interest in public policy. However, these two strands of development have tended to be treated as discrete discourses and have developed separately in policy. Nevertheless, it can hardly be assumed that what policy makers, service planners, providers and purchasers would value and prioritise as good quality would necessarily coincide with what service users would want. Developing effective partnership working needs to go beyond considerations of organisations and professional groupings, and fully involve service users as one of the key stakeholders. This paper describes the findings of three projects undertaken by Shaping Our Lives. These studies confirmed that service-user concepts of outcomes and quality may differ significantly from those currently employed; moreover, service users are able to offer a complex and sophisticated model of what outcome measures might look like if they were centrally involved in their definition and application. Nevertheless, service users currently have little impact in defining and influencing quality outcomes. The projects also highlight the importance of networking and knowledge sharing for service users and user organisations in their ability to influence policy definitions of quality, and a number of the barriers and obstacles which undermine this process. The paper concludes with two proposals which, considered together, offer the basis for taking forward effective and inclusive partnerships and developing measures for quality consistent with the rights and preferences of service users themselves. They are an essential complement to broader efforts and strategies to develop effective partnerships in health and social care.

Activity Monitors as Support for Older Persons' Physical Activity in Daily Life: Qualitative Study of the Users' Experiences.

PubMed

Ehn, Maria; Eriksson, Lennie Carlén; Åkerberg, Nina; Johansson, Ann-Christin

2018-02-01

Falls are a major threat to the health and independence of seniors. Regular physical activity (PA) can prevent 40% of all fall injuries. The challenge is to motivate and support seniors to be physically active. Persuasive systems can constitute valuable support for persons aiming at establishing and maintaining healthy habits. However, these systems need to support effective behavior change techniques (BCTs) for increasing older adults' PA and meet the senior users' requirements and preferences. Therefore, involving users as codesigners of new systems can be fruitful. Prestudies of the user's experience with similar solutions can facilitate future user-centered design of novel persuasive systems. The aim of this study was to investigate how seniors experience using activity monitors (AMs) as support for PA in daily life. The addressed research questions are as follows: (1) What are the overall experiences of senior persons, of different age and balance function, in using wearable AMs in daily life?; (2) Which aspects did the users perceive relevant to make the measurements as meaningful and useful in the long-term perspective?; and (3) What needs and requirements did the users perceive as more relevant for the activity monitors to be useful in a long-term perspective? This qualitative interview study included 8 community-dwelling older adults (median age: 83 years). The participants' experiences in using two commercial AMs together with tablet-based apps for 9 days were investigated. Activity diaries during the usage and interviews after the usage were exploited to gather user experience. Comments in diaries were summarized, and interviews were analyzed by inductive content analysis. The users (n=8) perceived that, by using the AMs, their awareness of own PA had increased. However, the AMs' impact on the users' motivation for PA and activity behavior varied between participants. The diaries showed that self-estimated physical effort varied between participants and varied for each individual over time. Additionally, participants reported different types of accomplished activities; talking walks was most frequently reported. To be meaningful, measurements need to provide the user with a reliable receipt of whether his or her current activity behavior is sufficient for reaching an activity goal. Moreover, praise when reaching a goal was described as motivating feedback. To be useful, the devices must be easy to handle. In this study, the users perceived wearables as easy to handle, whereas tablets were perceived difficult to maneuver. Users reported in the diaries that the devices had been functional 78% (58/74) of the total test days. Activity monitors can be valuable for supporting seniors' PA. However, the potential of the solutions for a broader group of seniors can significantly be increased. Areas of improvement include reliability, usability, and content supporting effective BCTs with respect to increasing older adults' PA. ©Maria Ehn, Lennie Carlén Eriksson, Nina Åkerberg, Ann-Christin Johansson. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 01.02.2018.

Hidden costs: the direct and indirect impact of user fees on access to malaria treatment and primary care in Mali.

PubMed

Johnson, Ari; Goss, Adeline; Beckerman, Jessica; Castro, Arachu

2012-11-01

About 20 years after initial calls for the introduction of user fees in health systems in sub-Saharan Africa, a growing coalition is advocating for their removal. Several African countries have abolished user fees for health care for some or all of their citizens. However, fee-for-service health care delivery remains a primary health care funding model in many countries in sub-Saharan Africa. Although the impact of user fees on utilization of health services and household finances has been studied extensively, further research is needed to characterize the multi-faceted health and social problems associated with charging user fees. This ethnographic study aims to identify consequences of user fees on gender inequality, food insecurity, and household decision-making for a group of women living in poverty. Ethnographic life history interviews were conducted with 24 women in Yirimadjo, Mali in 2007. Purposive sampling selected participants across a broad socio-economic spectrum. Semi-structured interviews addressed participants' past medical history, socio-economic status, social and family history, and access to health care. Interview transcripts were coded using the guiding analytical framework of structural violence. Interviews revealed that user fees for health care not only decreased utilization of health services, but also resulted in delayed presentation for care, incomplete or inadequate care, compromised food security and household financial security, and reduced agency for women in health care decision making. The effects of user fees were amplified by conditions of poverty, as well as gender and health inequality; user fees in turn reinforced the inequalities created by those very conditions. The qualitative data reveal multi-faceted health and socioeconomic effects of user fees, and illustrate that user fees for health care may impact quality of care, health outcomes, food insecurity, and gender inequality, in addition to impacting health care utilization and household finances. As many countries consider user fee abolition policies, these findings indicate the need to create a broader evaluation framework-one that can measure the health and socioeconomic impacts of user fee polices and of their removal. Copyright © 2012 Elsevier Ltd. All rights reserved.

Using a Smartphone App and Coaching Group Sessions to Promote Residents' Reflection in the Workplace.

PubMed

Könings, Karen D; van Berlo, Jean; Koopmans, Richard; Hoogland, Henk; Spanjers, Ingrid A E; ten Haaf, Jeroen A; van der Vleuten, Cees P M; van Merriënboer, Jeroen J G

2016-03-01

Reflecting on workplace-based experiences is necessary for professional development. However, residents need support to raise their awareness of valuable moments for learning and to thoughtfully analyze those learning moments afterwards. From October to December 2012, the authors held a multidisciplinary six-week postgraduate training module focused on general competencies. Residents were randomly assigned to one of four conditions with varying degrees of reflection support; they were offered (1) a smartphone app, (2) coaching group sessions, (3) a combination of both, or (4) neither type of support. The app allowed participants to capture in real time learning moments as a text note, audio recording, picture, or video. Coaching sessions held every two weeks aimed to deepen participants' reflection on captured learning moments. Questionnaire responses and reflection data were compared between conditions to assess the effects of the app and coaching sessions on intensity and frequency of reflection. Sixty-four residents participated. App users reflected more often, captured more learning moments, and reported greater learning progress than nonapp users. Participants who attended coaching sessions were more alert to learning moments and pursued more follow-up learning activities to improve on the general competencies. Those who received both types of support were most alert to these learning moments. A simple mobile app for capturing learning moments shows promise as a tool to support workplace-based learning, especially when combined with coaching sessions. Future research should evaluate these tools on a broader scale and in conjunction with residents' and students' personal digital portfolios.

An Overview of the Challenges with and Proposed Solutions for the Ingest and Distribution Processes For Airborne Data Management

NASA Astrophysics Data System (ADS)

Northup, E. A.; Beach, A. L., III; Early, A. B.; Kusterer, J.; Quam, B.; Wang, D.; Chen, G.

2015-12-01

The current data management practices for NASA airborne field projects have successfully served science team data needs over the past 30 years to achieve project science objectives, however, users have discovered a number of issues in terms of data reporting and format. The ICARTT format, a NASA standard since 2010, is currently the most popular among the airborne measurement community. Although easy for humans to use, the format standard is not sufficiently rigorous to be machine-readable, and there lacks a standard variable naming convention among the many airborne measurement variables. This makes data use and management tedious and resource intensive, and also create problems in Distributed Active Archive Center (DAAC) data ingest procedures and distribution. Further, most DAACs use metadata models that concentrate on satellite data observations, making them less prepared to deal with airborne data. There also exists a substantial amount of airborne data distributed by websites designed for science team use that are less friendly to users unfamiliar with operations of airborne field studies. A number of efforts are underway to help overcome the issues with airborne data discovery and distribution. The ICARTT Refresh Earth Science Data Systems Working Group (ESDSWG) was established to enable a platform for atmospheric science data providers, users, and data managers to collaborate on developing new criteria for the file format in an effort to enhance airborne data usability. In addition, the NASA Langley Research Center Atmospheric Science Data Center (ASDC) has developed the Toolsets for Airborne Data (TAD) to provide web-based tools and centralized access to airborne in situ measurements of atmospheric composition. This presentation will discuss the aforementioned challenges and attempted solutions in an effort to demonstrate how airborne data management can be improved to streamline data ingest and discoverability to a broader user community.

Parsimonious data: How a single Facebook like predicts voting behavior in multiparty systems.

PubMed

Kristensen, Jakob Bæk; Albrechtsen, Thomas; Dahl-Nielsen, Emil; Jensen, Michael; Skovrind, Magnus; Bornakke, Tobias

2017-01-01

This study shows how liking politicians' public Facebook posts can be used as an accurate measure for predicting present-day voter intention in a multiparty system. We highlight that a few, but selective digital traces produce prediction accuracies that are on par or even greater than most current approaches based upon bigger and broader datasets. Combining the online and offline, we connect a subsample of surveyed respondents to their public Facebook activity and apply machine learning classifiers to explore the link between their political liking behaviour and actual voting intention. Through this work, we show that even a single selective Facebook like can reveal as much about political voter intention as hundreds of heterogeneous likes. Further, by including the entire political like history of the respondents, our model reaches prediction accuracies above previous multiparty studies (60-70%). The main contribution of this paper is to show how public like-activity on Facebook allows political profiling of individual users in a multiparty system with accuracies above previous studies. Beside increased accuracies, the paper shows how such parsimonious measures allows us to generalize our findings to the entire population of a country and even across national borders, to other political multiparty systems. The approach in this study relies on data that are publicly available, and the simple setup we propose can with some limitations, be generalized to millions of users in other multiparty systems.

Tools in Support of Planning for Weather and Climate Extremes

NASA Astrophysics Data System (ADS)

Done, J.; Bruyere, C. L.; Hauser, R.; Holland, G. J.; Tye, M. R.

2016-12-01

A major limitation to planning for weather and climate extremes is the lack of maintained and readily available tools that can provide robust and well-communicated predictions and advice on their impacts. The National Center for Atmospheric Research is facilitating a collaborative international program to develop and support such tools within its Capacity Center for Climate and Weather Extremes aimed at improving community resilience planning and reducing weather and climate impacts. A Global Risk, Resilience and Impacts Toolbox is in development and will provide: A portable web-based interface to process work requests from a variety of users and locations; A sophisticated framework that enables specialized community tools to access a comprehensive database (public and private) of geo-located hazard, vulnerability, exposure, and loss data; A community development toolkit that enables and encourages community tool developments geared towards specific user man­agement and planning needs, and A comprehensive community sup­port facilitated by NCAR utilizing tutorials and a help desk. A number of applications are in development, built off the latest climate science, and in collaboration with private industry and local and state governments. Example applications will be described, including a hurricane damage tool in collaboration with the reinsurance sector, and a weather management tool for the construction industry. These examples will serve as starting points to discuss the broader potential of the toolbox.

Forensic hash for multimedia information

NASA Astrophysics Data System (ADS)

Lu, Wenjun; Varna, Avinash L.; Wu, Min

2010-01-01

Digital multimedia such as images and videos are prevalent on today's internet and cause significant social impact, which can be evidenced by the proliferation of social networking sites with user generated contents. Due to the ease of generating and modifying images and videos, it is critical to establish trustworthiness for online multimedia information. In this paper, we propose novel approaches to perform multimedia forensics using compact side information to reconstruct the processing history of a document. We refer to this as FASHION, standing for Forensic hASH for informatION assurance. Based on the Radon transform and scale space theory, the proposed forensic hash is compact and can effectively estimate the parameters of geometric transforms and detect local tampering that an image may have undergone. Forensic hash is designed to answer a broader range of questions regarding the processing history of multimedia data than the simple binary decision from traditional robust image hashing, and also offers more efficient and accurate forensic analysis than multimedia forensic techniques that do not use any side information.

WFIRST: Data/Instrument Simulation Support at IPAC

NASA Astrophysics Data System (ADS)

Laine, Seppo; Akeson, Rachel; Armus, Lee; Bennett, Lee; Colbert, James; Helou, George; Kirkpatrick, J. Davy; Meshkat, Tiffany; Paladini, Roberta; Ramirez, Solange; Wang, Yun; Xie, Joan; Yan, Lin

2018-01-01

As part of WFIRST Science Center preparations, the IPAC Science Operations Center (ISOC) maintains a repository of 1) WFIRST data and instrument simulations, 2) tools to facilitate scientific performance and feasibility studies using the WFIRST, and 3) parameters summarizing the current design and predicted performance of the WFIRST telescope and instruments. The simulation repository provides access for the science community to simulation code, tools, and resulting analyses. Examples of simulation code with ISOC-built web-based interfaces include EXOSIMS (for estimating exoplanet yields in CGI surveys) and the Galaxy Survey Exposure Time Calculator. In the future the repository will provide an interface for users to run custom simulations of a wide range of coronagraph instrument (CGI) observations and sophisticated tools for designing microlensing experiments. We encourage those who are generating simulations or writing tools for exoplanet observations with WFIRST to contact the ISOC team so we can work with you to bring these to the attention of the broader astronomical community as we prepare for the exciting science that will be enabled by WFIRST.

Advanced Virus Detection Technologies Interest Group (AVDTIG): Efforts on High Throughput Sequencing (HTS) for Virus Detection.

PubMed

Khan, Arifa S; Vacante, Dominick A; Cassart, Jean-Pol; Ng, Siemon H S; Lambert, Christophe; Charlebois, Robert L; King, Kathryn E

Several nucleic-acid based technologies have recently emerged with capabilities for broad virus detection. One of these, high throughput sequencing, has the potential for novel virus detection because this method does not depend upon prior viral sequence knowledge. However, the use of high throughput sequencing for testing biologicals poses greater challenges as compared to other newly introduced tests due to its technical complexities and big data bioinformatics. Thus, the Advanced Virus Detection Technologies Users Group was formed as a joint effort by regulatory and industry scientists to facilitate discussions and provide a forum for sharing data and experiences using advanced new virus detection technologies, with a focus on high throughput sequencing technologies. The group was initiated as a task force that was coordinated by the Parenteral Drug Association and subsequently became the Advanced Virus Detection Technologies Interest Group to continue efforts for using new technologies for detection of adventitious viruses with broader participation, including international government agencies, academia, and technology service providers. © PDA, Inc. 2016.

R classes and methods for SNP array data.

PubMed

Scharpf, Robert B; Ruczinski, Ingo

2010-01-01

The Bioconductor project is an "open source and open development software project for the analysis and comprehension of genomic data" (1), primarily based on the R programming language. Infrastructure packages, such as Biobase, are maintained by Bioconductor core developers and serve several key roles to the broader community of Bioconductor software developers and users. In particular, Biobase introduces an S4 class, the eSet, for high-dimensional assay data. Encapsulating the assay data as well as meta-data on the samples, features, and experiment in the eSet class definition ensures propagation of the relevant sample and feature meta-data throughout an analysis. Extending the eSet class promotes code reuse through inheritance as well as interoperability with other R packages and is less error-prone. Recently proposed class definitions for high-throughput SNP arrays extend the eSet class. This chapter highlights the advantages of adopting and extending Biobase class definitions through a working example of one implementation of classes for the analysis of high-throughput SNP arrays.

Evidence of Neurotoxicity of Ecstasy: Sustained Effects on Electroencephalographic Activity in Polydrug Users

PubMed Central

Adamaszek, Michael; Khaw, Alexander V.; Buck, Ulrike; Andresen, Burghard; Thomasius, Rainer

2010-01-01

Objective According to previous EEG reports of indicative disturbances in Alpha and Beta activities, a systematic search for distinct EEG abnormalities in a broader population of Ecstasy users may especially corroborate the presumed specific neurotoxicity of Ecstasy in humans. Methods 105 poly-drug consumers with former Ecstasy use and 41 persons with comparable drug history without Ecstasy use, and 11 drug naives were investigated for EEG features. Conventional EEG derivations of 19 electrodes according to the 10-20-system were conducted. Besides standard EEG bands, quantitative EEG analyses of 1-Hz-subdivided power ranges of Alpha, Theta and Beta bands have been considered. Results Ecstasy users with medium and high cumulative Ecstasy doses revealed an increase in Theta and lower Alpha activities, significant increases in Beta activities, and a reduction of background activity. Ecstasy users with low cumulative Ecstasy doses showed a significant Alpha activity at 11 Hz. Interestingly, the spectral power of low frequencies in medium and high Ecstasy users was already significantly increased in the early phase of EEG recording. Statistical analyses suggested the main effect of Ecstasy to EEG results. Conclusions Our data from a major sample of Ecstasy users support previous data revealing alterations of EEG frequency spectrum due rather to neurotoxic effects of Ecstasy on serotonergic systems in more detail. Accordingly, our data may be in line with the observation of attentional and memory impairments in Ecstasy users with moderate to high misuse. Despite the methodological problem of polydrug use also in our approach, our EEG results may be indicative of the neuropathophysiological background of the reported memory and attentional deficits in Ecstasy abusers. Overall, our findings may suggest the usefulness of EEG in diagnostic approaches in assessing neurotoxic sequela of this common drug abuse. PMID:21124854

The CPEX Data Portal: Bringing Together Different Types of Data for Different Types of Users

NASA Astrophysics Data System (ADS)

Knosp, B.; Li, P.; Vu, Q. A.; Hristova-Veleva, S. M.; Turk, J.; Lambrigtsen, B.

2017-12-01

The NASA Convective Processes Experiment (CPEX) aircraft field campaign took place in the summer of 2017 in the North Atlantic / Caribbean Ocean region. During this campaign, the NASA DC-8 aircraft carried several instruments that took measurements with the goal of collecting data to help answer questions about convective storm initiation, organization, growth, and dissipation. To help researchers answer science questions about convective storms, the CPEX Data Portal (https://cpexportal.jpl.nasa.gov) was created to bring together relevant satellite and model data, along with aircraft data observed during the campaign. The CPEX Data Portal was designed for two major functions: 1) assist with mission planning by providing a near real-time snapshot of what was going on in the broader North Atlantic domain and 2) bring together different types of data after the aircraft flights had finished to allow researchers to dive deeper into the data. Both functions necessitated collecting a host of disparate data from different instrument types that inherently have differences in resolution, spatial and temporal domain, and quality. Additionally, users of this data portal had varying levels of experience with the different data types (e.g. some used aircraft data before, but not with satellite data). Users were also at different points in their careers - both students and seasoned researchers participated in the campaign and brought different understandings of the physical processes depicted in the portal's visualizations. The CPEX Data Portal team used the existing JPL Tropical Cyclone Information System's near real-time data portal software package to launch a campaign-specific portal to host data during and after the CPEX campaign. This web-based portal includes the ability to visualize pre-generated images of physical quantities from satellites, models, and aircraft instruments, and brings them together in a common virtual globe for given spatial and temporal criteria. Users can also utilize on-line analysis tools to further interrogate the data. In this talk, we will describe how the CPEX Data Portal was able to curate campaign-relevant data, display different types of data in different ways, and make the data digestible and informative for different types of Earth science data user communities.

Development of a web-based intervention for the indicated prevention of depression.

PubMed

Kelders, Saskia M; Pots, Wendy T M; Oskam, Maarten Jan; Bohlmeijer, Ernst T; van Gemert-Pijnen, Julia E W C

2013-02-20

To reduce the large public health burden of the high prevalence of depression, preventive interventions targeted at people at risk are essential and can be cost-effective. Web-based interventions are able to provide this care, but there is no agreement on how to best develop these applications and often the technology is seen as a given. This seems to be one of the main reasons that web-based interventions do not reach their full potential. The current study describes the development of a web-based intervention for the indicated prevention of depression, employing the CeHRes (Center for eHealth Research and Disease Management) roadmap. The goals are to create a user-friendly application which fits the values of the stakeholders and to evaluate the process of development. The employed methods are a literature scan and discussion in the contextual inquiry; interviews, rapid prototyping and a requirement session in the value specification stage; and user-based usability evaluation, expert-based usability inspection and a requirement session in the design stage. The contextual inquiry indicated that there is a need for easily accessible interventions for the indicated prevention of depression and web-based interventions are seen as potentially meeting this need. The value specification stage yielded expected needs of potential participants, comments on the usefulness of the proposed features and comments on two proposed designs of the web-based intervention. The design stage yielded valuable comments on the system, content and service of the web-based intervention. Overall, we found that by developing the technology, we successfully (re)designed the system, content and service of the web-based intervention to match the values of stakeholders. This study has shown the importance of a structured development process of a web-based intervention for the indicated prevention of depression because: (1) it allows the development team to clarify the needs that have to be met for the intervention to be of use to the target audience; and (2) it yields feedback on the design of the application that is broader than color and buttons, but encompasses comments on the quality of the service that the application offers.

Development of a web-based intervention for the indicated prevention of depression

PubMed Central

2013-01-01

Background To reduce the large public health burden of the high prevalence of depression, preventive interventions targeted at people at risk are essential and can be cost-effective. Web-based interventions are able to provide this care, but there is no agreement on how to best develop these applications and often the technology is seen as a given. This seems to be one of the main reasons that web-based interventions do not reach their full potential. The current study describes the development of a web-based intervention for the indicated prevention of depression, employing the CeHRes (Center for eHealth Research and Disease Management) roadmap. The goals are to create a user-friendly application which fits the values of the stakeholders and to evaluate the process of development. Methods The employed methods are a literature scan and discussion in the contextual inquiry; interviews, rapid prototyping and a requirement session in the value specification stage; and user-based usability evaluation, expert-based usability inspection and a requirement session in the design stage. Results The contextual inquiry indicated that there is a need for easily accessible interventions for the indicated prevention of depression and web-based interventions are seen as potentially meeting this need. The value specification stage yielded expected needs of potential participants, comments on the usefulness of the proposed features and comments on two proposed designs of the web-based intervention. The design stage yielded valuable comments on the system, content and service of the web-based intervention. Conclusions Overall, we found that by developing the technology, we successfully (re)designed the system, content and service of the web-based intervention to match the values of stakeholders. This study has shown the importance of a structured development process of a web-based intervention for the indicated prevention of depression because: (1) it allows the development team to clarify the needs that have to be met for the intervention to be of use to the target audience; and (2) it yields feedback on the design of the application that is broader than color and buttons, but encompasses comments on the quality of the service that the application offers. PMID:23425322

Do I Really Sound Like That? Communicating Earthquake Science Following Significant Earthquakes at the NEIC

NASA Astrophysics Data System (ADS)

Hayes, G. P.; Earle, P. S.; Benz, H.; Wald, D. J.; Yeck, W. L.

2017-12-01

The U.S. Geological Survey's National Earthquake Information Center (NEIC) responds to about 160 magnitude 6.0 and larger earthquakes every year and is regularly inundated with information requests following earthquakes that cause significant impact. These requests often start within minutes after the shaking occurs and come from a wide user base including the general public, media, emergency managers, and government officials. Over the past several years, the NEIC's earthquake response has evolved its communications strategy to meet the changing needs of users and the evolving media landscape. The NEIC produces a cascade of products starting with basic hypocentral parameters and culminating with estimates of fatalities and economic loss. We speed the delivery of content by prepositioning and automatically generating products such as, aftershock plots, regional tectonic summaries, maps of historical seismicity, and event summary posters. Our goal is to have information immediately available so we can quickly address the response needs of a particular event or sequence. This information is distributed to hundreds of thousands of users through social media, email alerts, programmatic data feeds, and webpages. Many of our products are included in event summary posters that can be downloaded and printed for local display. After significant earthquakes, keeping up with direct inquiries and interview requests from TV, radio, and print reports is always challenging. The NEIC works with the USGS Office of Communications and the USGS Science Information Services to organize and respond to these requests. Written executive summaries reports are produced and distributed to USGS personnel and collaborators throughout the country. These reports are updated during the response to keep our message consistent and information up to date. This presentation will focus on communications during NEIC's rapid earthquake response but will also touch on the broader USGS traditional and social media presence.

Reuse of Software Assets for the NASA Earth Science Decadal Survey Missions

NASA Technical Reports Server (NTRS)

Mattmann, Chris A.; Downs, Robert R.; Marshall, James J.; Most, Neal F.; Samadi, Shahin

2010-01-01

Software assets from existing Earth science missions can be reused for the new decadal survey missions that are being planned by NASA in response to the 2007 Earth Science National Research Council (NRC) Study. The new missions will require the development of software to curate, process, and disseminate the data to science users of interest and to the broader NASA mission community. In this paper, we discuss new tools and a blossoming community that are being developed by the Earth Science Data System (ESDS) Software Reuse Working Group (SRWG) to improve capabilities for reusing NASA software assets.

Open Source and Design Thinking at NASA: A Vision for Future Software

NASA Technical Reports Server (NTRS)

Trimble, Jay

2017-01-01

NASA Mission Control Software for the Visualization of data has historically been closed, accessible only to small groups of flight controllers, often bound to a specific mission discipline such as flight dynamics, health and status or mission planning. Open Mission Control Technologies (MCT) provides new capability for NASA mission controllers and, by being fully open source, opens up NASA software for the visualization of mission data to broader communities inside and outside of NASA. Open MCT is the product of a design thinking process within NASA, using participatory design and design sprints to build a product that serves users.

Program management model study

NASA Technical Reports Server (NTRS)

Connelly, J. J.; Russell, J. E.; Seline, J. R.; Sumner, N. R., Jr.

1972-01-01

Two models, a system performance model and a program assessment model, have been developed to assist NASA management in the evaluation of development alternatives for the Earth Observations Program. Two computer models were developed and demonstrated on the Goddard Space Flight Center Computer Facility. Procedures have been outlined to guide the user of the models through specific evaluation processes, and the preparation of inputs describing earth observation needs and earth observation technology. These models are intended to assist NASA in increasing the effectiveness of the overall Earth Observation Program by providing a broader view of system and program development alternatives.

Towards the creation of a European Network of Earth Observation Networks within GEO. The ConnectinGEO project.

NASA Astrophysics Data System (ADS)

Masó, Joan; Serral, Ivette; Menard, Lionel; Wald, Lucien; Nativi, Stefano; Plag, Hans-Peter; Jules-Plag, Shelley; Nüst, Daniel; Jirka, Simon; Pearlman, Jay; De Maziere, Martine

2015-04-01

ConnectinGEO (Coordinating an Observation Network of Networks EnCompassing saTellite and IN-situ to fill the Gaps in European Observations" is a new H2020 Coordination and Support Action with the primary goal of linking existing Earth Observation networks with science and technology (S&T) communities, the industry sector, the Group on Earth Observations (GEO), and Copernicus. ConnectinGEO aims to facilitate a broader and more accessible knowledge base to support the needs of GEO, its Societal Benefit Areas (SBAs) and the users of the Global Earth Observing System of Systems (GEOSS). A broad range of subjects from climate, natural resources and raw materials, to the emerging UN Sustainable Development Goals (SDGs) will be addressed. The project will generate a prioritized list of critical gaps within available observation data and models to translate observations into practice-relevant knowledge, based on stakeholder consultation and systematic analysis. Ultimately, it will increase coherency of European observation networks, increase the use of Earth observations for assessments and forecasts and inform the planning for future observation systems. ConnectinGEO will initiate a European Network of Earth Observation Networks (ENEON) that will encompass space-based, airborne and in-situ observations networks. ENEON will be composed by project partners representing thematic observation networks along with the GEOSS Science and Technology Stakeholder Network, GEO Communities of Practices, Copernicus services, Sentinel missions and in-situ support data representatives, representatives of the space-based, airborne and in-situ observations European networks (e.g. EPOS, EMSO and GROOM, etc), representatives of the industry sector and European and national funding agencies, in particular those participating in the future ERA-PlaNET. At the beginning, the ENEON will be created and managed by the project. Then the management will be transferred to the network itself to ensure its future continuity. ConnectinGEO's main goal in ENEON is to mature a consultation complemented by a systematic analysis of available data and metadata, which will draw for the first time a coherent picture of the variety of used data interfaces, policies and indicators. This way, the project will stimulate a harmonized and coherent coverage of the European EO networks, reemphasizing the political strategic targets, create opportunities for SMEs to develop products based on the current networks, and open avenue for industry to participate in investments addressing the identified high-priority gaps. The project starts in February 2015 and will last two years. We will present the five threads of the project for gap analysis in the Earth observation networks: global requirements and goals, international research programs, consultation process, systematic analysis of existing data platforsm and industry challenges. The presentation will provide both an overview of the network concepts and approaches and discuss participation of the broader scientific community of data providers and users.

A Broader and Bolder Approach Uses Education to Break the Cycle of Poverty

ERIC Educational Resources Information Center

Noguera, Pedro A.

2011-01-01

In Newark, N.J. the Broader, Bolder Approach (BBA) reform plan is developing a comprehensive school reform strategy. Operating in seven schools in Newark's Central Ward, BBA has introduced school-based interventions that are responsive to the issues and challenges. Through these interventions, social services, and a concerted effort to increase…

Possibilities of the Positive Following Violence and Trauma: Informing the Coming Decade of Research

ERIC Educational Resources Information Center

Ai, Amy L.; Park, Crystal L.

2005-01-01

The effects of trauma and violence may be better understood by taking a broader perspective that includes resilience and recovery as well as damage and symptomatology. Based on this broader view, this article describes three interrelated, cutting-edge trends in mental health research: (a) the positive psychology movement, (b) the recognition of…

There's More to Ethics than Justice and Harm: Teaching a Broader Understanding of Journalism Ethics

ERIC Educational Resources Information Center

Knowlton, Steven; McKinley, J. Christopher

2016-01-01

Most applied ethics training in journalism in the West follows Enlightenment-era, reason-based ethical principles: Justice is intrinsically better than injustice (Kant), and the best choice is achieving the best outcome for all concerned (Mill). Recent scholarship in ethics suggests that ethics is much broader than this. This article examines a…

Desire to Be Underweight: Exploratory Study on a Weight Loss App Community and User Perceptions of the Impact on Disordered Eating Behaviors

PubMed Central

Reddy, Madhu C; Booth, Kayla M; Kvasny, Lynette; Blair, Johnna L; Li, Victor; Poole, Erika S

2017-01-01

Background Mobile health (mHealth) apps for weight loss (weight loss apps) can be useful diet and exercise tools for individuals in need of losing weight. Most studies view weight loss app users as these types of individuals, but not all users have the same needs. In fact, users with disordered eating behaviors who desire to be underweight are also utilizing weight loss apps; however, few studies give a sense of the prevalence of these users in weight loss app communities and their perceptions of weight loss apps in relation to disordered eating behaviors. Objective The aim of this study was to provide an analysis of users’ body mass indices (BMIs) in a weight loss app community and examples of how users with underweight BMI goals perceive the impact of the app on disordered eating behaviors. Methods We focused on two aspects of a weight loss app (DropPounds): profile data and forum posts, and we moved from a broader picture of the community to a narrower focus on users’ perceptions. We analyzed profile data to better understand the goal BMIs of all users, highlighting the prevalence of users with underweight BMI goals. Then we explored how users with a desire to be underweight discussed the weight loss app’s impact on disordered eating behaviors. Results We found three main results: (1) no user (regardless of start BMI) starts with a weight gain goal, and most users want to lose weight; (2) 6.78% (1261/18,601) of the community want to be underweight, and most identify as female; (3) users with underweight BMI goals tend to view the app as positive, especially for reducing bingeing; however, some acknowledge its role in exacerbating disordered eating behaviors. Conclusions These findings are important for our understanding of the different types of users who utilize weight loss apps, the perceptions of weight loss apps related to disordered eating, and how weight loss apps may impact users with a desire to be underweight. Whereas these users had underweight goals, they often view the app as helpful in reducing disordered eating behaviors, which led to additional questions. Therefore, future research is needed. PMID:29025694

YTPdb: a wiki database of yeast membrane transporters.

PubMed

Brohée, Sylvain; Barriot, Roland; Moreau, Yves; André, Bruno

2010-10-01

Membrane transporters constitute one of the largest functional categories of proteins in all organisms. In the yeast Saccharomyces cerevisiae, this represents about 300 proteins ( approximately 5% of the proteome). We here present the Yeast Transport Protein database (YTPdb), a user-friendly collaborative resource dedicated to the precise classification and annotation of yeast transporters. YTPdb exploits an evolution of the MediaWiki web engine used for popular collaborative databases like Wikipedia, allowing every registered user to edit the data in a user-friendly manner. Proteins in YTPdb are classified on the basis of functional criteria such as subcellular location or their substrate compounds. These classifications are hierarchical, allowing queries to be performed at various levels, from highly specific (e.g. ammonium as a substrate or the vacuole as a location) to broader (e.g. cation as a substrate or inner membranes as location). Other resources accessible for each transporter via YTPdb include post-translational modifications, K(m) values, a permanently updated bibliography, and a hierarchical classification into families. The YTPdb concept can be extrapolated to other organisms and could even be applied for other functional categories of proteins. YTPdb is accessible at http://homes.esat.kuleuven.be/ytpdb/. Copyright © 2010 Elsevier B.V. All rights reserved.

WholeCellSimDB: a hybrid relational/HDF database for whole-cell model predictions

PubMed Central

Karr, Jonathan R.; Phillips, Nolan C.; Covert, Markus W.

2014-01-01

Mechanistic ‘whole-cell’ models are needed to develop a complete understanding of cell physiology. However, extracting biological insights from whole-cell models requires running and analyzing large numbers of simulations. We developed WholeCellSimDB, a database for organizing whole-cell simulations. WholeCellSimDB was designed to enable researchers to search simulation metadata to identify simulations for further analysis, and quickly slice and aggregate simulation results data. In addition, WholeCellSimDB enables users to share simulations with the broader research community. The database uses a hybrid relational/hierarchical data format architecture to efficiently store and retrieve both simulation setup metadata and results data. WholeCellSimDB provides a graphical Web-based interface to search, browse, plot and export simulations; a JavaScript Object Notation (JSON) Web service to retrieve data for Web-based visualizations; a command-line interface to deposit simulations; and a Python API to retrieve data for advanced analysis. Overall, we believe WholeCellSimDB will help researchers use whole-cell models to advance basic biological science and bioengineering. Database URL: http://www.wholecellsimdb.org Source code repository URL: http://github.com/CovertLab/WholeCellSimDB PMID:25231498

Reconstruction of vessel structures from serial whole slide sections of murine liver samples

NASA Astrophysics Data System (ADS)

Schwier, Michael; Hahn, Horst K.; Dahmen, Uta; Dirsch, Olaf

2013-03-01

Image-based analysis of the vascular structures of murine liver samples is an important tool for scientists to understand liver physiology and morphology. Typical assessment methods are MicroCT, which allows for acquiring images of the whole organ while lacking resolution for fine details, and confocal laser scanning microscopy, which allows detailed insights into fine structures while lacking the broader context. Imaging of histological serial whole slide sections is a recent technology able to fill this gap, since it provides a fine resolution up to the cellular level, but on a whole organ scale. However, whole slide imaging is a modality providing only 2D images. Therefore the challenge is to use stacks of serial sections from which to reconstruct the 3D vessel structures. In this paper we present a semi-automatic procedure to achieve this goal. We employ an automatic method that detects vessel structures based on continuity and shape characteristics. Furthermore it supports the user to perform manual corrections where required. With our methods we were able to successfully extract and reconstruct vessel structures from a stack of 100 and a stack of 397 serial sections of a mouse liver lobe, thus proving the potential of our approach.

Characterizing Uncertainty and Variability in PBPK Models ...

EPA Pesticide Factsheets

Mode-of-action based risk and safety assessments can rely upon tissue dosimetry estimates in animals and humans obtained from physiologically-based pharmacokinetic (PBPK) modeling. However, risk assessment also increasingly requires characterization of uncertainty and variability; such characterization for PBPK model predictions represents a continuing challenge to both modelers and users. Current practices show significant progress in specifying deterministic biological models and the non-deterministic (often statistical) models, estimating their parameters using diverse data sets from multiple sources, and using them to make predictions and characterize uncertainty and variability. The International Workshop on Uncertainty and Variability in PBPK Models, held Oct 31-Nov 2, 2006, sought to identify the state-of-the-science in this area and recommend priorities for research and changes in practice and implementation. For the short term, these include: (1) multidisciplinary teams to integrate deterministic and non-deterministic/statistical models; (2) broader use of sensitivity analyses, including for structural and global (rather than local) parameter changes; and (3) enhanced transparency and reproducibility through more complete documentation of the model structure(s) and parameter values, the results of sensitivity and other analyses, and supporting, discrepant, or excluded data. Longer-term needs include: (1) theoretic and practical methodological impro

SBMLmod: a Python-based web application and web service for efficient data integration and model simulation.

PubMed

Schäuble, Sascha; Stavrum, Anne-Kristin; Bockwoldt, Mathias; Puntervoll, Pål; Heiland, Ines

2017-06-24

Systems Biology Markup Language (SBML) is the standard model representation and description language in systems biology. Enriching and analysing systems biology models by integrating the multitude of available data, increases the predictive power of these models. This may be a daunting task, which commonly requires bioinformatic competence and scripting. We present SBMLmod, a Python-based web application and service, that automates integration of high throughput data into SBML models. Subsequent steady state analysis is readily accessible via the web service COPASIWS. We illustrate the utility of SBMLmod by integrating gene expression data from different healthy tissues as well as from a cancer dataset into a previously published model of mammalian tryptophan metabolism. SBMLmod is a user-friendly platform for model modification and simulation. The web application is available at http://sbmlmod.uit.no , whereas the WSDL definition file for the web service is accessible via http://sbmlmod.uit.no/SBMLmod.wsdl . Furthermore, the entire package can be downloaded from https://github.com/MolecularBioinformatics/sbml-mod-ws . We envision that SBMLmod will make automated model modification and simulation available to a broader research community.

The national suicide prevention strategy for England: the reality of a national strategy for the nursing profession.

PubMed

Anderson, M; Jenkins, R

2006-12-01

Suicide is recognized as a global phenomenon and many countries now have national suicide prevention strategies. International guidance on suicide prevention and accepted epidemiological and treatment-based research underpins healthcare policy relating to suicide reduction. There has been an established comprehensive strategy in England since 2002. However, the rate of suicide continues to be a concern and nurses hold a key role in the implementation of national, regional and local policy into practice. The aim of this paper is to consider the current implications of the national suicide prevention strategy in England for nursing. This discussion paper draws upon both empirical evidence-based literature, governmental guidance and policy-related documentation. The national suicide prevention strategy for England currently continues to have a multifaceted impact on the nursing profession. This ranges from clinical practice issues such as risk assessment through to broader public health responsibilities. If nurses and allied health professionals are to be effective in their role within suicide prevention, they will need to be supported in building awareness of the wider context of the national policy. In particular, this will mean working effectively and collaboratively with the voluntary sector, service users and other non-medical agencies.

Training at the Gym, Training for Life: Creating Better Versions of the Self Through Exercise

PubMed Central

Doğan, Ceren

2015-01-01

The present study draws on Scott’s (2011) notion of the Re-Inventive Institution and explores how gym members make sense and give meaning to their exercise regime. Overall, it is argued that for many participants gym exercise is more than physical training; it is also training for life. Based on a thematic analysis of 32 semi-structured interviews it is argued that gym workout is a means to create better versions of the self on mainly three levels. First, gym participants perceive themselves to be efficient and productive in general. Second, gym training is believed to increase the control they have over their lives. Third, gym members associate their gym workout with amplified emotional resilience, believing that fitness workout makes them not only fitter in a physical sense but also fitter and better equipped in a psychological sense. Surprisingly, a small group of regular gym users displayed more critical sentiments and distanced themselves from the images and values the gym stands for. The results of this study can be linked to broader political discourses on health and fitness that make use of corporate managerial vocabularies and are based on ideals of rationalization and efficiency. PMID:27247669

Shared decision making for psychiatric medication management: beyond the micro-social.

PubMed

Morant, Nicola; Kaminskiy, Emma; Ramon, Shulamit

2016-10-01

Mental health care has lagged behind other health-care domains in developing and applying shared decision making (SDM) for treatment decisions. This is despite compatibilities with ideals of modern mental health care such as self-management and recovery-oriented practice, and growing policy-level interest. Psychiatric medication is a mainstay of mental health treatment, but there are known problems with prescribing practices, and service users report feeling uninvolved in medication decisions and concerned about adverse effects. SDM has potential to produce better tailoring of psychiatric medication to individuals' needs. This conceptual review argues that several aspects of mental health care that differ from other health-care contexts (e.g. forms of coercion, questions about service users' insight and disempowerment) may impact on processes and possibilities for SDM. It is therefore problematic to uncritically import models of SDM developed in other health-care contexts. We argue that decision making for psychiatric medication is better understood in a broader way that moves beyond the micro-social focus of a medical consultation. Contextualizing specific medication-related consultations within longer term relationships, and broader service systems enables recognition of the multiple processes, actors and agendas that shape how psychiatric medication is prescribed, managed and used, and which may facilitate or impede SDM. A broad conceptualization of decision making for psychiatric medication that moves beyond the micro-social can account for why SDM in this domain remains a rarity. It has both conceptual and practical utility for evaluating research evidence, identifying future research priorities and highlighting fruitful ways of developing and implementing SDM in mental health care. © 2015 The Authors Health Expectations Published by John Wiley & Sons Ltd.

J-Earth: An Essential Resource for Terrestrial Remote Sensing and Data Analysis

NASA Astrophysics Data System (ADS)

Dunn, S.; Rupp, J.; Cheeseman, S.; Christensen, P. R.; Prashad, L. C.; Dickenshied, S.; Anwar, S.; Noss, D.; Murray, K.

2011-12-01

There is a need for a software tool that has the ability to display and analyze various types of earth science and social data through a simple, user-friendly interface. The J-Earth software tool has been designed to be easily accessible for download and intuitive use, regardless of the technical background of the user base. This tool does not require courses or text books to learn to use, yet is powerful enough to allow a more general community of users to perform complex data analysis. Professions that will benefit from this tool range from geologists, geographers, and climatologists to sociologists, economists, and ecologists as well as policy makers. J-Earth was developed by the Arizona State University Mars Space Flight Facility as part of the JMARS (Java Mission-planning and Analysis for Remote Sensing) suite of open-source tools. The program is a Geographic Information Systems (GIS) application used for viewing and processing satellite and airborne remote sensing data. While the functionality of JMARS has historically focused on the research needs of the planetary science community, J-Earth has been designed for a much broader Earth-based user audience. NASA instrument products accessible within J-Earth include data from ASTER, GOES, Landsat, MODIS, and TIMS. While J-Earth contains exceptionally comprehensive and high resolution satellite-derived data and imagery, this tool also includes many socioeconomic data products from projects lead by international organizations and universities. Datasets used in J-Earth take the form of grids, rasters, remote sensor "stamps", maps, and shapefiles. Some highly demanded global datasets available within J-Earth include five levels of administrative/political boundaries, climate data for current conditions as well as models for future climates, population counts and densities, land cover/land use, and poverty indicators. While this application does share the same powerful functionality of JMARS, J-Earth's apperance is enhanced for much easier data analysis. J-Earth utilizes a layering system to view data from different sources which can then be exported, scaled, colored and superimposed for quick comparisons. Users may now perform spatial analysis over several diverse datasets with respect to a defined geographic area or the entire globe. In addition, several newly acquired global datasets contain a temporal dimension which when accessed through J-Earth, make this a unique and powerful tool for spatial analysis over time. The functionality and ease of use set J-Earth apart from all other terrestrial GIS software packages and enable endless social, political, and scientific possibilities

Understanding and valuing the broader health system benefits of Uganda's national Human Resources for Health Information System investment.

PubMed

Driessen, Julia; Settle, Dykki; Potenziani, David; Tulenko, Kate; Kabocho, Twaha; Wadembere, Ismail

2015-08-31

To address the need for timely and comprehensive human resources for health (HRH) information, governments and organizations have been actively investing in electronic health information interventions, including in low-resource settings. The economics of human resources information systems (HRISs) in low-resource settings are not well understood, however, and warrant investigation and validation. This case study describes Uganda's Human Resources for Health Information System (HRHIS), implemented with support from the US Agency for International Development, and documents perceptions of its impact on the health labour market against the backdrop of the costs of implementation. Through interviews with end users and implementers in six different settings, we document pre-implementation data challenges and consider how the HRHIS has been perceived to affect human resources decision-making and the healthcare employment environment. This multisite case study documented a range of perceived benefits of Uganda's HRHIS through interviews with end users that sought to capture the baseline (or pre-implementation) state of affairs, the perceived impact of the HRHIS and the monetary value associated with each benefit. In general, the system appears to be strengthening both demand for health workers (through improved awareness of staffing patterns) and supply (by improving licensing, recruitment and competency of the health workforce). This heightened ability to identify high-value employees makes the health sector more competitive for high-quality workers, and this elevation of the health workforce also has broader implications for health system performance and population health. Overall, it is clear that HRHIS end users in Uganda perceived the system to have significantly improved day-to-day operations as well as longer term institutional mandates. A more efficient and responsive approach to HRH allows the health sector to recruit the best candidates, train employees in needed skills and deploy trained personnel to facilities where there is real demand. This cascade of benefits can extend the impact and rewards of working in the health sector, which elevates the health system as a whole.

School-based diagnosis and treatment of malaria by teachers using rapid diagnostic tests and artemisinin-based combination therapy: experiences and perceptions of users and implementers of the Learner Treatment Kit, southern Malawi.

PubMed

Mphwatiwa, Treza; Witek-McManus, Stefan; Mtali, Austin; Okello, George; Nguluwe, Paul; Chatsika, Hard; Roschnik, Natalie; Halliday, Katherine E; Brooker, Simon J; Mathanga, Don P

2017-08-07

Training teachers to diagnose uncomplicated malaria using malaria rapid diagnostic tests and treat with artemisinin-based combination therapy has the potential to improve the access of primary school children (6-14 years) to prompt and efficient treatment for malaria, but little is known about the acceptability of such an intervention. This qualitative study explored experiences and perceptions of users and implementers of a programme of school-based malaria case management via a first-aid kit-the Learner Treatment Kit (LTK)-implemented as part of a cluster-randomized controlled trial in Zomba district, Malawi. From 29 primary schools where teachers were trained to test and treat school children for malaria using the LTK, six schools were purposively selected on the basis of relative intervention usage (low, medium or high); school size and geographical location. In total eight focus group discussions were held with school children, parents and guardians, and teachers; and 20 in-depth interviews were conducted with key stakeholders at the school, district and national levels. Interviews were recorded, transcribed, and analysed using a thematic analysis approach. The LTK was widely perceived by respondents to be a worthwhile intervention, with the opinion that trained teachers were trusted providers of malaria testing and treatment to school children. Benefits of the programme included a perception of improved access to malaria treatment for school children; decreased school absenteeism; and that the programme supported broader national health and education policies. Potential barriers to successful implementation expressed included increased teacher workloads, a feeling of inadequate supervision from health workers, lack of incentives and concerns for the sustainability of the programme regarding the supply of drugs and commodities. Training teachers to test for and treat uncomplicated malaria in schools was well received by both users and implementers alike, and was perceived by the majority of stakeholders to be a valuable programme. Factors raised as critical to the success of such a programme included ensuring an effective supervisory system, a reliable supply chain, and the training of greater numbers of teachers per school to manage high consultation numbers, especially during the peak malaria transmission season.

Imagining value, imagining users: academic technology transfer for health innovation.

PubMed

Miller, Fiona Alice; Sanders, Carrie B; Lehoux, Pascale

2009-04-01

Governments have invested heavily in the clinical and economic promise of health innovation and express increasing concern with the efficacy and efficiency of the health innovation system. In considering strategies for 'better' health innovation, policy makers and researchers have taken a particular interest in the work of universities and related public research organizations: How do these organizations identify and transfer promising innovations to market, and do these efforts make best use of public sector investments? We conducted an ethnographic study of technology transfer offices (TTOs) in Ontario and British Columbia, Canada, to consider the place of health and health system imperatives in judgments of value in early-stage health innovation. Our analysis suggests that the valuation process is poorly specified as a set of task-specific judgments. Instead, we argue that technology transfer professionals are active participants in the construction of the innovation and assign value by 'imagining' the end product in its 'context of use'. Oriented as they are to the commercialization of health technology, TTOs understand users primarily as market players. The immediate users of TTOs' efforts are commercial partners (i.e., licensees, investors) who are capable of translating current discoveries into future commodities. The ultimate end users - patients, clinicians, health systems - are the future consumers of the products to be sold. Attention to these proximate and more distal users in the valuation process is a complex and constitutive feature of the work of health technology transfer. At the same time, judgements about individual technologies are made in relation to a broader imperative through which TTOs seek to imagine and construct sustainable innovation systems. Judgments of value are rendered sensible in relation to the logic of valuation for systems of innovation that, in turn, configure users of health innovation in systemic ways.

[Optimising the rehabilitation discharge report of the German statutory pension insurance: the recipients' and users' perspectives].

PubMed

Ahnert, J; Ladwig, J; Holderied, A; Brüggemann, S; Vogel, H

2014-06-01

Given the significance of documentation and information transfer in the health-care system as well as new technological options, there is a need for continuously modifying and enhancing the pension insurance's rehabilitation discharge report while taking into account the benefits and expenses associated with it. Among the regular discharge report recipients/users are general practitioners, medical specialists, socio-medical consultants of the German pension insurance and other health-care providers and funding agencies (e. g., statutory health insurance, federal labour agency), external socio-medical consultants, judges in charge of social legislation issues, pension insurance administrators, and rehabilitation quality assurance officials. In the context of a broader project on the optimisation of the pension insurance's rehabilitation discharge report, the specific needs and interests of its recipients/users as well as suggestions concerning the improvement of structure and content of the discharge report were assessed. Discharge report recipients/users were asked via questionnaire to indicate how frequently they use certain information from the report for their work. They were also asked to state objections/areas of concern and sugges­tions for improvement. 400 recipients/users filled in the questionnaire. More than half of the respondents considered the discharge report too long. Sugges­tions for shortening the report centred on avoiding redundancies and including standardised response items instead of free text passages. User groups differed with regard to the content that should be subject to reductions. The non-representative sample notwithstanding, the survey's results have rendered important starting points for optimising the statutory pension insurance's discharge report. © Georg Thieme Verlag KG Stuttgart · New York.

A Scientist's Guide to Achieving Broader Impacts through K-12 STEM Collaboration.

PubMed

Komoroske, Lisa M; Hameed, Sarah O; Szoboszlai, Amber I; Newsom, Amanda J; Williams, Susan L

2015-03-01

The National Science Foundation and other funding agencies are increasingly requiring broader impacts in grant applications to encourage US scientists to contribute to science education and society. Concurrently, national science education standards are using more inquiry-based learning (IBL) to increase students' capacity for abstract, conceptual thinking applicable to real-world problems. Scientists are particularly well suited to engage in broader impacts via science inquiry outreach, because scientific research is inherently an inquiry-based process. We provide a practical guide to help scientists overcome obstacles that inhibit their engagement in K-12 IBL outreach and to attain the accrued benefits. Strategies to overcome these challenges include scaling outreach projects to the time available, building collaborations in which scientists' research overlaps with curriculum, employing backward planning to target specific learning objectives, encouraging scientists to share their passion, as well as their expertise with students, and transforming institutional incentives to support scientists engaging in educational outreach.

EARTH SYSTEM ATLAS: A Platform for Access to Peer-Reviewed Information about process and change in the Earth System

NASA Astrophysics Data System (ADS)

Sahagian, D.; Prentice, C.

2004-12-01

A great deal of time, effort and resources have been expended on global change research to date, but dissemination and visualization of the key pertinent data sets has been problematical. Toward that end, we are constructing an Earth System Atlas which will serve as a single compendium describing the state of the art in our understanding of the Earth system and how it has responded to and is likely to respond to natural and anthropogenic perturbations. The Atlas is an interactive web-based system of data bases and data manipulation tools and so is much more than a collection of pre-made maps posted on the web. It represents a tool for assembling, manipulating, and displaying specific data as selected and customized by the user. Maps are created "on the fly" according to user-specified instructions. The information contained in the Atlas represents the growing body of data assembled by the broader Earth system research community, and can be displayed in the form of maps and time series of the various relevant parameters that drive and are driven by changes in the Earth system at various time scales. The Atlas is designed to display the information assembled by the global change research community in the form of maps and time series of all the relevant parameters that drive or are driven by changes in the Earth System at various time scales. This will serve to provide existing data to the community, but also will help to highlight data gaps that may hinder our understanding of critical components of the Earth system. This new approach to handling Earth system data is unique in several ways. First and foremost, data must be peer-reviewed. Further, it is designed to draw on the expertise and products of extensive international research networks rather than on a limited number of projects or institutions. It provides explanatory explanations targeted to the user's needs, and the display of maps and time series can be customize by the user. In general, the Atlas is designed provide the research community with a new opportunity for data observation and manipulation, enabling new scientific discoveries in the coming years. An initial prototype of the Atlas has been developed and can be manipulated in real time.

Modeling Interdependent and Periodic Real-World Action Sequences

PubMed Central

Kurashima, Takeshi; Althoff, Tim; Leskovec, Jure

2018-01-01

Mobile health applications, including those that track activities such as exercise, sleep, and diet, are becoming widely used. Accurately predicting human actions in the real world is essential for targeted recommendations that could improve our health and for personalization of these applications. However, making such predictions is extremely difficult due to the complexities of human behavior, which consists of a large number of potential actions that vary over time, depend on each other, and are periodic. Previous work has not jointly modeled these dynamics and has largely focused on item consumption patterns instead of broader types of behaviors such as eating, commuting or exercising. In this work, we develop a novel statistical model, called TIPAS, for Time-varying, Interdependent, and Periodic Action Sequences. Our approach is based on personalized, multivariate temporal point processes that model time-varying action propensities through a mixture of Gaussian intensities. Our model captures short-term and long-term periodic interdependencies between actions through Hawkes process-based self-excitations. We evaluate our approach on two activity logging datasets comprising 12 million real-world actions (e.g., eating, sleep, and exercise) taken by 20 thousand users over 17 months. We demonstrate that our approach allows us to make successful predictions of future user actions and their timing. Specifically, TIPAS improves predictions of actions, and their timing, over existing methods across multiple datasets by up to 156%, and up to 37%, respectively. Performance improvements are particularly large for relatively rare and periodic actions such as walking and biking, improving over baselines by up to 256%. This demonstrates that explicit modeling of dependencies and periodicities in real-world behavior enables successful predictions of future actions, with implications for modeling human behavior, app personalization, and targeting of health interventions. PMID:29780977

Interacting forms of expertise in security governance: the example of CCTV surveillance at Geneva International Airport.

PubMed

Klauser, Francisco

2009-06-01

The paper investigates the multiple public-private exchanges and cooperation involved in the installation and development of CCTV surveillance at Geneva International Airport. Emphasis is placed on the interacting forms of authority and expertise of five parties: the user(s), owner and supplier of the camera system, as well as the technical managers of the airport and the Swiss regulatory bodies in airport security. While placing the issues of airport surveillance in the particular context of a specific range of projects and transformations relating to the developments of CCTV at Geneva Airport, the paper not only provides important insights into the micro-politics of surveillance at Geneva Airport, but aims to re-institute these as part of a broader 'problematic': the mediating role of expertise and the growing functional fragmentation of authority in contemporary security governance. On this basis, the paper also exemplifies the growing mutual interdependences between security and business interests in the ever growing 'surveillant assemblage' in contemporary security governance.

A content analysis of Camel Snus advertisements in print media.

PubMed

Timberlake, David S; Pechmann, Cornelia; Tran, Sarah Y; Au, Vanessa

2011-06-01

Researchers have questioned whether the R.J. Reynolds Tobacco Company is marketing Camel Snus as a product for nontobacco users, smokeless-tobacco users, or cigarette smokers. The objective of this study was to examine advertisements of Camel Snus in print media to determine the most likely audience of intent. A content analysis was conducted among Camel Snus advertisements printed in newspaper and consumer magazines between July 2007 and August 2010. The advertisements (n = 83 distinct; N = 458 total) were identified from a comprehensive search of a proprietary database maintained by TNS Media Intelligence. Results indicated that all advertisements, published between July 2007 and September 2009, were intended to promote a tobacco product for cigarette smokers. A shift in marketing strategy occurred from October 2009 to the present time with publication of the "Break Free" magazine advertisements, characterized by an ambiguous message that could conceivably appeal to any group, including nontobacco users (e.g., adolescents), smokeless-tobacco users, and/or cigarette smokers. However, an examination of the consumer magazines advertising Camel Snus indicated a demographically diverse readership in terms of gender, age, and education, suggesting that the advertisements are less likely to be intended for smokeless-tobacco users. These findings validate other reports and editorials, suggesting that Camel Snus was being marketed as a product for smokers at the time of the product's national debut. The recent shift to the "Break Free" marketing campaign may reflect an attempt to enhance the image of the Camel brand in order to attract a broader spectrum of consumers.

Assessing user preferences for e-readers and tablets.

PubMed

Le Ber, Jeanne M; Lombardo, Nancy T; Honisett, Amy; Jones, Peter Stevens; Weber, Alice

2013-01-01

Librarians purchased 12 e-readers and six tablets to provide patrons the opportunity to experiment with the latest mobile technologies. After several train-the-trainer sessions, librarians shared device information with the broader health sciences community. Devices were cataloged and made available for a two-week checkout. A limited number of books and applications (apps) were preloaded for all the devices, and patrons were allowed to download their own content. Each tablet has Google Books, iBooks, Kindle, and Nook apps available to allow choice in reading e-books. Upon return, patrons were asked to complete a ten-question survey to determine preferences for device use.

High rate information systems - Architectural trends in support of the interdisciplinary investigator

NASA Technical Reports Server (NTRS)

Handley, Thomas H., Jr.; Preheim, Larry E.

1990-01-01

Data systems requirements in the Earth Observing System (EOS) Space Station Freedom (SSF) eras indicate increasing data volume, increased discipline interplay, higher complexity and broader data integration and interpretation. A response to the needs of the interdisciplinary investigator is proposed, considering the increasing complexity and rising costs of scientific investigation. The EOS Data Information System, conceived to be a widely distributed system with reliable communication links between central processing and the science user community, is described. Details are provided on information architecture, system models, intelligent data management of large complex databases, and standards for archiving ancillary data, using a research library, a laboratory and collaboration services.

Circadian course of the P300 ERP in patients with amyotrophic lateral sclerosis - implications for brain-computer interfaces (BCI).

PubMed

Erlbeck, Helena; Mochty, Ursula; Kübler, Andrea; Real, Ruben G L

2017-01-07

Accidents or neurodegenerative diseases like amyotrophic lateral sclerosis (ALS) can lead to progressing, extensive, and complete paralysis leaving patients aware but unable to communicate (locked-in state). Brain-computer interfaces (BCI) based on electroencephalography represent an important approach to establish communication with these patients. The most common BCI for communication rely on the P300, a positive deflection arising in response to rare events. To foster broader application of BCIs for restoring lost function, also for end-users with impaired vision, we explored whether there were specific time windows during the day in which a P300 driven BCI should be preferably applied. The present study investigated the influence of time of the day and modality (visual vs. auditory) on P300 amplitude and latency. A sample of 14 patients (end-users) with ALS and 14 healthy age matched volunteers participated in the study and P300 event-related potentials (ERP) were recorded at four different times (10, 12 am, 2, & 4 pm) during the day. Results indicated no differences in P300 amplitudes or latencies between groups (ALS patients v. healthy participants) or time of measurement. In the auditory condition, latencies were shorter and amplitudes smaller as compared to the visual condition. Our findings suggest applicability of EEG/BCI sessions in patients with ALS throughout normal waking hours. Future studies using actual BCI systems are needed to generalize these findings with regard to BCI effectiveness/efficiency and other times of day.

Parsimonious data: How a single Facebook like predicts voting behavior in multiparty systems

PubMed Central

Albrechtsen, Thomas; Dahl-Nielsen, Emil; Jensen, Michael; Skovrind, Magnus

2017-01-01

This study shows how liking politicians’ public Facebook posts can be used as an accurate measure for predicting present-day voter intention in a multiparty system. We highlight that a few, but selective digital traces produce prediction accuracies that are on par or even greater than most current approaches based upon bigger and broader datasets. Combining the online and offline, we connect a subsample of surveyed respondents to their public Facebook activity and apply machine learning classifiers to explore the link between their political liking behaviour and actual voting intention. Through this work, we show that even a single selective Facebook like can reveal as much about political voter intention as hundreds of heterogeneous likes. Further, by including the entire political like history of the respondents, our model reaches prediction accuracies above previous multiparty studies (60–70%). The main contribution of this paper is to show how public like-activity on Facebook allows political profiling of individual users in a multiparty system with accuracies above previous studies. Beside increased accuracies, the paper shows how such parsimonious measures allows us to generalize our findings to the entire population of a country and even across national borders, to other political multiparty systems. The approach in this study relies on data that are publicly available, and the simple setup we propose can with some limitations, be generalized to millions of users in other multiparty systems. PMID:28931023

Development of regional climate scenarios in the Netherlands - involvement of users

NASA Astrophysics Data System (ADS)

Bessembinder, Janette; Overbeek, Bernadet

2013-04-01

Climate scenarios are consistent and plausible pictures of possible future climates. They are intended for use in studies exploring the impacts of climate change, and to formulate possible adaptation strategies. To ensure that the developed climate scenarios are relevant to the intended users, interaction with the users is needed. As part of the research programmes "Climate changes Spatial Planning" and "Knowledge for Climate" several projects on climate services, tailoring of climate information and communication were conducted. Some of the important lessons learned about user interaction are: *) To be able to deliver relevant climate information in the right format, proper knowledge is required on who will be using the climate information and data, how it will be used and why they use it; *) Users' requirements can be very diverse and requirements may change over time. Therefore, sustained (personal) contact with users is required; *) Organising meetings with climate researchers and users of climate information together, and working together in projects results in mutual understanding on the requirements of users and the limitations to deliver certain types of climate information, which facilitates the communication and results in more widely accepted products; *) Information and communication should be adapted to the type of users (e.g. impact researchers or policy makers) and to the type of problem (unstructured problems require much more contact with the users). In 2001 KNMI developed climate scenarios for the National Commission on Water management in the 21st century (WB21 scenarios). In 2006 these were replaced by a the KNMI'06 scenarios, intended for a broader group of users. The above lessons are now taken into account during the development of the next generation of climate scenarios for the Netherlands, expected at the end of 2013, after the publication of the IPCC WG1 report: *) users' requirements are taken into account explicitly in the whole process of the development of the climate scenarios; *) users are involved already in the early phases of the development of new scenarios, among others in the following way: **) workshops on users' requirements to check whether they have changed and to get more information; **) feedback group of users to get more detailed feedback on the modes of communication; **) newsletter with information on the progress and procedures to be followed and separate workshops for researchers and policy makers with different levels of detail; **) projects together with impact researchers: tailoring of data and in order to be able to present impact information consistent with the climate scenarios much earlier. During the presentation more detailed information will be given on the interaction with users.

Mobile Phone Assessment in Egocentric Networks: A Pilot Study on Gay Men and Their Peers

PubMed Central

Comulada, W. Scott

2015-01-01

Mobile phone-based data collection encompasses the richness of social network research. Both individual-level and network-level measures can be recorded. For example, health-related behaviors can be reported via mobile assessment. Social interactions can be assessed by phone-log data. Yet the potential of mobile phone data collection has largely been untapped. This is especially true of egocentric studies in public health settings where mobile phones can enhance both data collection and intervention delivery, e.g. mobile users can video chat with counselors. This is due in part to privacy issues and other barriers that are more difficult to address outside of academic settings where most mobile research to date has taken place. In this article, we aim to inform a broader discussion on mobile research. In particular, benefits and challenges to mobile phone-based data collection are highlighted through our mobile phone-based pilot study that was conducted on egocentric networks of 12 gay men (n = 44 total participants). HIV-transmission and general health behaviors were reported through a mobile phone-based daily assessment that was administered through study participants’ own mobile phones. Phone log information was collected from gay men with Android phones. Benefits and challenges to mobile implementation are discussed, along with the application of multi-level models to the type of longitudinal egocentric data that we collected. PMID:25844003

Mobile Phone Assessment in Egocentric Networks: A Pilot Study on Gay Men and Their Peers.

PubMed

Comulada, W Scott

2014-12-01

Mobile phone-based data collection encompasses the richness of social network research. Both individual-level and network-level measures can be recorded. For example, health-related behaviors can be reported via mobile assessment. Social interactions can be assessed by phone-log data. Yet the potential of mobile phone data collection has largely been untapped. This is especially true of egocentric studies in public health settings where mobile phones can enhance both data collection and intervention delivery, e.g. mobile users can video chat with counselors. This is due in part to privacy issues and other barriers that are more difficult to address outside of academic settings where most mobile research to date has taken place. In this article, we aim to inform a broader discussion on mobile research. In particular, benefits and challenges to mobile phone-based data collection are highlighted through our mobile phone-based pilot study that was conducted on egocentric networks of 12 gay men (n = 44 total participants). HIV-transmission and general health behaviors were reported through a mobile phone-based daily assessment that was administered through study participants' own mobile phones. Phone log information was collected from gay men with Android phones. Benefits and challenges to mobile implementation are discussed, along with the application of multi-level models to the type of longitudinal egocentric data that we collected.

Shifting Practices Toward Recovery-Oriented Care Through an E-Recovery Portal in Community Mental Health Care: A Mixed-Methods Exploratory Study.

PubMed

Gammon, Deede; Strand, Monica; Eng, Lillian Sofie; Børøsund, Elin; Varsi, Cecilie; Ruland, Cornelia

2017-05-02

Mental health care is shifting from a primary focus on symptom reduction toward personal recovery-oriented care, especially for persons with long-term mental health care needs. Web-based portals may facilitate this shift, but little is known about how such tools are used or the role they may play in personal recovery. The aim was to illustrate uses and experiences with the secure e-recovery portal "ReConnect" as an adjunct to ongoing community mental health care and explore its potential role in shifting practices toward recovery. ReConnect was introduced into two Norwegian mental health care communities and used for 6 months. The aim was to support personal recovery and collaboration between service users and health care providers. Among inclusion criteria for participation were long-term care needs and at least one provider willing to interact with service users through ReConnect. The portal was designed to support ongoing collaboration as each service user-provider dyad/team found appropriate and consisted of (1) a toolbox of resources for articulating and working with recovery processes, such as status/goals/activities relative to life domains (eg, employment, social network, health), medications, network map, and exercises (eg, sleep hygiene, mindfulness); (2) messaging with providers who had partial access to toolbox content; and (3) a peer support forum. Quantitative data (ie, system log, questionnaires) were analyzed using descriptive statistics. Qualitative data (eg, focus groups, forum postings) are presented relative to four recovery-oriented practice domains: personally defined recovery, promoting citizenship, working relationships, and organizational commitment. Fifty-six participants (29 service users and 27 providers) made up 29 service user-provider dyads. Service users reported having 11 different mental health diagnoses, with a median 2 (range 1-7) diagnoses each. The 27 providers represented nine different professional backgrounds. The forum was the most frequently used module with 1870 visits and 542 postings. Service users' control over toolbox resources (eg, defining and working toward personal goals), coupled with peer support, activated service users in their personal recovery processes and in community engagement. Some providers (30%, 8/27) did not interact with service users through ReConnect. Dyads that used the portal resources did so in highly diverse ways, and participants reported needing more than 6 months to discover and adapt optimal uses relative to their individual and collaborative needs. Regardless of providers' portal use, service users' control over toolbox resources, coupled with peer support, offered an empowering common frame of reference that represented a shift toward recovery-oriented practices within communities. Although service users' autonomous use of the portal can eventually influence providers in the direction of recovery practices, a fundamental shift is unlikely without broader organizational commitments aligned with recovery principles (eg, quantified goals for service user involvement in care plans). ©Deede Gammon, Monica Strand, Lillian Sofie Eng, Elin Børøsund, Cecilie Varsi, Cornelia Ruland. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 02.05.2017.

Data Discovery of Big and Diverse Climate Change Datasets - Options, Practices and Challenges

NASA Astrophysics Data System (ADS)

Palanisamy, G.; Boden, T.; McCord, R. A.; Frame, M. T.

2013-12-01

Developing data search tools is a very common, but often confusing, task for most of the data intensive scientific projects. These search interfaces need to be continually improved to handle the ever increasing diversity and volume of data collections. There are many aspects which determine the type of search tool a project needs to provide to their user community. These include: number of datasets, amount and consistency of discovery metadata, ancillary information such as availability of quality information and provenance, and availability of similar datasets from other distributed sources. Environmental Data Science and Systems (EDSS) group within the Environmental Science Division at the Oak Ridge National Laboratory has a long history of successfully managing diverse and big observational datasets for various scientific programs via various data centers such as DOE's Atmospheric Radiation Measurement Program (ARM), DOE's Carbon Dioxide Information and Analysis Center (CDIAC), USGS's Core Science Analytics and Synthesis (CSAS) metadata Clearinghouse and NASA's Distributed Active Archive Center (ORNL DAAC). This talk will showcase some of the recent developments for improving the data discovery within these centers The DOE ARM program recently developed a data discovery tool which allows users to search and discover over 4000 observational datasets. These datasets are key to the research efforts related to global climate change. The ARM discovery tool features many new functions such as filtered and faceted search logic, multi-pass data selection, filtering data based on data quality, graphical views of data quality and availability, direct access to data quality reports, and data plots. The ARM Archive also provides discovery metadata to other broader metadata clearinghouses such as ESGF, IASOA, and GOS. In addition to the new interface, ARM is also currently working on providing DOI metadata records to publishers such as Thomson Reuters and Elsevier. The ARM program also provides a standards based online metadata editor (OME) for PIs to submit their data to the ARM Data Archive. USGS CSAS metadata Clearinghouse aggregates metadata records from several USGS projects and other partner organizations. The Clearinghouse allows users to search and discover over 100,000 biological and ecological datasets from a single web portal. The Clearinghouse also enabled some new data discovery functions such as enhanced geo-spatial searches based on land and ocean classifications, metadata completeness rankings, data linkage via digital object identifiers (DOIs), and semantically enhanced keyword searches. The Clearinghouse also currently working on enabling a dashboard which allows the data providers to look at various statistics such as number their records accessed via the Clearinghouse, most popular keywords, metadata quality report and DOI creation service. The Clearinghouse also publishes metadata records to broader portals such as NSF DataONE and Data.gov. The author will also present how these capabilities are currently reused by the recent and upcoming data centers such as DOE's NGEE-Arctic project. References: [1] Devarakonda, R., Palanisamy, G., Wilson, B. E., & Green, J. M. (2010). Mercury: reusable metadata management, data discovery and access system. Earth Science Informatics, 3(1-2), 87-94. [2]Devarakonda, R., Shrestha, B., Palanisamy, G., Hook, L., Killeffer, T., Krassovski, M., ... & Frame, M. (2014, October). OME: Tool for generating and managing metadata to handle BigData. In BigData Conference (pp. 8-10).

Section 3: Quality and Value-Based Requirements

NASA Astrophysics Data System (ADS)

Mylopoulos, John

Traditionally, research and practice in software engineering has focused its attention on specific software qualities, such as functionality and performance. According to this perspective, a system is deemed to be of good quality if it delivers all required functionality (“fitness-for-purpose”) and its performance is above required thresholds. Increasingly, primarily in research but also in practice, other qualities are attracting attention. To facilitate evolution, maintainability and adaptability are gaining popularity. Usability, universal accessibility, innovativeness, and enjoyability are being studied as novel types of non-functional requirements that we do not know how to define, let alone accommodate, but which we realize are critical under some contingencies. The growing importance of the business context in the design of software-intensive systems has also thrust economic value, legal compliance, and potential social and ethical implications into the forefront of requirements topics. A focus on the broader user environment and experience, as well as the organizational and societal implications of system use, thus has become more central to the requirements discourse. This section includes three contributions to this broad and increasingly important topic.

[The interaction in clinical nursing education: reflections on care of the person with hypertension].

PubMed

Araújo-Girão, Ana L; Martins de Oliveira, Glória Y; Gomes, Emiliana B; Parente-Arruda, Lidyane; Aires de Freitas, Consuelo H

2015-01-01

To identify the knowledge and attitudes about self-care in health among users who received clinical nursing education for hypertension based on the level of knowledge and attitudes of the hypertensive patient through interactive care interventions with patients and relatives in the therapeutic context, with the goal of developing health education. This study represents action research with a qualitative approach on hypertensive patients hospitalized for stroke. Hypertension as a risk factor is most strongly associated with the development of this health problem. Participants were interviewed about their knowledge about the illness before and after the realization of individualized health education activities on the basis of the theory of symbolic interactionism. It was found that the respondents, after participating in the educational process, demonstrated a broader knowledge of hypertension, which motivated them to seek changes in habits that could improve their quality of life. Through the use of symbolic interactionism, health education proved to be a strategy for empowerment and autonomy of the hypertensive subject with respect to their treatment and can be integrated into nursing care.

Implementation science for the prevention and treatment of HIV/AIDS.

PubMed

Schackman, Bruce R

2010-12-01

Implementation science is the scientific study of methods to promote the integration of research findings and evidence-based interventions into health care policy and practice and hence to improve the quality and effectiveness of health services and care. Implementation science is distinguished from monitoring and evaluation by its emphasis on the use of the scientific method. The origins of implementation science include operations research, industrial engineering, and management science. Today, implementation science encompasses a broader range of methods and skills including decision science and operations research, health systems research, health outcomes research, health and behavioral economics, epidemiology, statistics, organization and management science, finance, policy analysis, anthropology, sociology, and ethics. Examples of implementation science research are presented for HIV prevention (prevention of mother-to-child transmission of HIV, male circumcision) and HIV and drug use (syringe distribution, treating drug users with antiretroviral therapy and opioid substitution therapy). For implementation science to become an established field in HIV/AIDS research, there needs to be better coordination between funders of research and funders of program delivery and greater consensus on scientific research approaches and standards of evidence.

[SYSTEMATIZATION, ORDER AND SECURITY AS A RESULT OF THE NURSE ASSESSMENT IN PAEDIATRIC EMERGENCY: A METAMORPHOSIS PROCESS].

PubMed

García-Hernández, M-Noelia; Fraga-Hernández, Ma Elena; Mahtani-Chugani, Vinita

2014-12-01

To determine from the health care professionals perspective the impact on clinical practice of incorporating an assessment tool for primary care paediatric emergency. Qualitative study based on the collection of written documents. Twenty-four wide and detailed documents were collected. Thematic analysis was used. Participants were 9 nurses and 7 paediatricians, all with experience in the Paediatric Emergency Department. The results are grouped into three areas: perception of previous situation; benefits perceived; difficulties of the change process related to the triage instrument. The benefits perceived include the achievement of the objectives related to triage as well as collateral benefits for the organization and distribution of structural resources, adequacy of human resources, self-assessment and professional recognition, improvement of team communication and users service perception. The difficulties identified are related to the feasibility of using this instrument when patient flow is high and to the need of specialized training. All participants perceived more benefits than disadvantages, and both nurses and paediatricians experienced the process as a positive experience. The introduction of the assessment tool had a broader impact than expected.

Broader color gamut of color-modulating optical coating display based on indium tin oxide and phase change materials.

PubMed

Ni, Zhigang; Mou, Shenghong; Zhou, Tong; Cheng, Zhiyuan

2018-05-01

A color-modulating optical coating display based on phase change materials (PCM) and indium tin oxide (ITO) is fabricated and analyzed. We demonstrate that altering the thickness of top-ITO in this PCM-based display device can effectively change color. The significant role of the top-ITO layer in the thin-film interference in this multilayer system is confirmed by experiment as well as simulation. The ternary-color modulation of devices with only 5 nano thin layer of phase change material is achieved. Furthermore, simulation work demonstrates that a stirringly broader color gamut can be obtained by introducing the control of the top-ITO thickness.

Understanding self-harm and suicide websites: a qualitative interview study of young adult website users.

PubMed

Baker, Darren; Fortune, Sarah

2008-01-01

Self-harm and suicide websites have been heavily criticized both in the literature and the wider media, despite the fact that very little is known about them. To date, no study has interviewed users of these sites about them. This qualitative study aims to explore the accounts of young adults who engage in self-harming and suicidal behaviors and use websites dedicated to these issues, in order to develop a broader understanding of these websites and to identify potential implications for future research. In-depth interviews were conducted via e-mail with 10 participants, who were recruited directly from self-harm and suicide websites. Using discourse analysis, we identified three main ways in which participants wrote about the sites. They constructed them as sources of empathy and understanding, as communities, and as a way of coping with social and psychological distress. These discourses gave users access to important, socially valued identities, such as being understood, belonging to a community and coping with their problems. If health professionals and researchers hope to understand people who use self-harm and suicide websites, and engage them in their services, they must take a more balanced view and not focus solely on the possible risks associated with using such sites.

Diamond Light Source: status and perspectives.

PubMed

Materlik, Gerhard; Rayment, Trevor; Stuart, David I

2015-03-06

Diamond Light Source, a third-generation synchrotron radiation (SR) facility in the UK, celebrated its 10th anniversary in 2012. A private limited company was set up in April 2002 to plan, construct and operate the new user-oriented SR facility, called in brief Diamond. It succeeded the Synchrotron Radiation Source in Daresbury, a second-generation synchrotron that opened in 1980 as the world's first dedicated X-ray-providing facility, closing finally in 2008, by which time Diamond's accelerators and first beamlines were operating and user experiments were under way. This theme issue of Philosophical Transactions of the Royal Society A gives some examples of the rich diversity of research done in the initial five years, with some glimpses of activity up to 2014. Speakers at the 10 year anniversary symposium were drawn from a small number of major thematic areas and each theme was elaborated by a few speakers whose contributions were placed into a broader context by a leading member of the UK academic community in the role of rapporteur. This introduction gives a summary of the design choices and strategic planning of Diamond as a coherent user facility, a snapshot of its present status and some consideration of future perspectives. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

With whom do you feel most intimate?: Exploring the quality of Facebook friendships in relation to similarities and interaction behaviors.

PubMed

Wee, Jieun; Lee, Joonhwan

2017-01-01

It is widely accepted that people tend to associate more and feel closer to those who share similar attributes with themselves. Most of the research on the phenomenon has been carried out in face-to-face contexts. However, it is necessary to study the phenomenon in computer-mediated contexts as well. Exploring Facebook is important in that friendships within the network indicate a broader spectrum of friends, ranging from complete strangers to confiding relations. Also, since diverse communication methods are available on Facebook, which method a user adopts to interact with a "friend" could influence the quality of the relationship, i.e. intimacy. Thus, current research aims to test whether people in computer-mediated contexts do perceive more intimacy toward friends who share similar traits, and further, aims to examine which interaction methods influence the closeness of relationship by collecting activity data of users on Facebook. Results from current study show traits related to intimacy in the online context of Facebook. Moreover, in addition to the interaction type itself, direction of the interaction influenced how intimate users feel towards their friends. Overall findings suggest that further investigation on the dynamics of online communication methods used in developing and maintaining relationships is necessary.

With whom do you feel most intimate?: Exploring the quality of Facebook friendships in relation to similarities and interaction behaviors

PubMed Central

Wee, Jieun; Lee, Joonhwan

2017-01-01

It is widely accepted that people tend to associate more and feel closer to those who share similar attributes with themselves. Most of the research on the phenomenon has been carried out in face-to-face contexts. However, it is necessary to study the phenomenon in computer-mediated contexts as well. Exploring Facebook is important in that friendships within the network indicate a broader spectrum of friends, ranging from complete strangers to confiding relations. Also, since diverse communication methods are available on Facebook, which method a user adopts to interact with a “friend” could influence the quality of the relationship, i.e. intimacy. Thus, current research aims to test whether people in computer-mediated contexts do perceive more intimacy toward friends who share similar traits, and further, aims to examine which interaction methods influence the closeness of relationship by collecting activity data of users on Facebook. Results from current study show traits related to intimacy in the online context of Facebook. Moreover, in addition to the interaction type itself, direction of the interaction influenced how intimate users feel towards their friends. Overall findings suggest that further investigation on the dynamics of online communication methods used in developing and maintaining relationships is necessary. PMID:28453526

The use of engineering design scenarios to assess student knowledge of global, societal, economic, and environmental contexts

NASA Astrophysics Data System (ADS)

McKenna, Ann F.; Hynes, Morgan M.; Johnson, Amy M.; Carberry, Adam R.

2016-07-01

Product archaeology as an educational approach asks engineering students to consider and explore the broader societal and global impacts of a product's manufacturing, distribution, use, and disposal on people, economics, and the environment. This study examined the impact of product archaeology in a project-based engineering design course on student attitudes and perceptions about engineering and abilities to extend and refine knowledge about broader contexts. Two design scenarios were created: one related to dental hygiene and one related to vaccination delivery. Design scenarios were used to (1) assess knowledge of broader contexts, and (2) test variability of student responses across different contextual situations. Results from pre- to post-surveying revealed improved student perceptions of knowledge of broader contexts. Significant differences were observed between the two design scenarios. The findings support the assumption that different design scenarios elicit consideration of different contexts and design scenarios can be constructed to target specific contextual considerations.

The cost of virtual wins: An examination of gambling-related risks in youth who spend money on social casino games

PubMed Central

King, Daniel L.; Russell, Alex; Gainsbury, Sally; Delfabbro, Paul H.; Hing, Nerilee

2016-01-01

Background and aims Social casino games (SCGs) are not technically considered a form of gambling but they do enable players to spend money in a game that is gambling themed or structurally approximate to gambling. It has been theorized that SCGs could be a gateway to gambling activities or otherwise normalize the experience of gambling for young people, particularly when money becomes involved. The aim of this study was to investigate whether adolescents’ financial expenditure in SCGs was associated with broader gambling activity, including level of participation, expenditure, and problem gambling symptoms. Methods An online survey was administered to 555 adolescents, including 130 SCG players (78 non-paying and 52 paying users). Results Paying SCG users tended to be employed males who play more frequently and engage in more SCG activities, who report more symptoms of problem gambling and higher psychological distress than non-paying SCG users. Paying SCG users reported more frequent engagement and spending in monetary gambling activities, and two-thirds of SCG payers recalled that their SCG use had preceded involvement in financial gambling. Discussion and conclusions Spending in simulated gambling activities by adolescents may be a risk factor for problem gambling. Although SCGs may currently defy classification as a form of gambling, these activities will likely continue to be scrutinized by regulators for the use of dubious or exploitative payment features offered in a gambling-themed format that is available to persons of all ages. PMID:27648743

The cost of virtual wins: An examination of gambling-related risks in youth who spend money on social casino games.

PubMed

King, Daniel L; Russell, Alex; Gainsbury, Sally; Delfabbro, Paul H; Hing, Nerilee

2016-09-01

Background and aims Social casino games (SCGs) are not technically considered a form of gambling but they do enable players to spend money in a game that is gambling themed or structurally approximate to gambling. It has been theorized that SCGs could be a gateway to gambling activities or otherwise normalize the experience of gambling for young people, particularly when money becomes involved. The aim of this study was to investigate whether adolescents' financial expenditure in SCGs was associated with broader gambling activity, including level of participation, expenditure, and problem gambling symptoms. Methods An online survey was administered to 555 adolescents, including 130 SCG players (78 non-paying and 52 paying users). Results Paying SCG users tended to be employed males who play more frequently and engage in more SCG activities, who report more symptoms of problem gambling and higher psychological distress than non-paying SCG users. Paying SCG users reported more frequent engagement and spending in monetary gambling activities, and two-thirds of SCG payers recalled that their SCG use had preceded involvement in financial gambling. Discussion and conclusions Spending in simulated gambling activities by adolescents may be a risk factor for problem gambling. Although SCGs may currently defy classification as a form of gambling, these activities will likely continue to be scrutinized by regulators for the use of dubious or exploitative payment features offered in a gambling-themed format that is available to persons of all ages.

ISED: Constructing a high-resolution elevation road dataset from massive, low-quality in-situ observations derived from geosocial fitness tracking data.

PubMed

McKenzie, Grant; Janowicz, Krzysztof

2017-01-01

Gaining access to inexpensive, high-resolution, up-to-date, three-dimensional road network data is a top priority beyond research, as such data would fuel applications in industry, governments, and the broader public alike. Road network data are openly available via user-generated content such as OpenStreetMap (OSM) but lack the resolution required for many tasks, e.g., emergency management. More importantly, however, few publicly available data offer information on elevation and slope. For most parts of the world, up-to-date digital elevation products with a resolution of less than 10 meters are a distant dream and, if available, those datasets have to be matched to the road network through an error-prone process. In this paper we present a radically different approach by deriving road network elevation data from massive amounts of in-situ observations extracted from user-contributed data from an online social fitness tracking application. While each individual observation may be of low-quality in terms of resolution and accuracy, taken together they form an accurate, high-resolution, up-to-date, three-dimensional road network that excels where other technologies such as LiDAR fail, e.g., in case of overpasses, overhangs, and so forth. In fact, the 1m spatial resolution dataset created in this research based on 350 million individual 3D location fixes has an RMSE of approximately 3.11m compared to a LiDAR-based ground-truth and can be used to enhance existing road network datasets where individual elevation fixes differ by up to 60m. In contrast, using interpolated data from the National Elevation Dataset (NED) results in 4.75m RMSE compared to the base line. We utilize Linked Data technologies to integrate the proposed high-resolution dataset with OpenStreetMap road geometries without requiring any changes to the OSM data model.

Mapping actions to improve access to medicines for mental disorders in low and middle income countries.

PubMed

Barbui, C; Dua, T; Kolappa, K; Saraceno, B; Saxena, S

2017-10-01

In recent years a number of intergovernmental initiatives have been activated in order to enhance the capacity of countries to improve access to essential medicines, particularly for mental disorders. In May 2013 the 66th World Health Assembly adopted the World Health Organization (WHO) Comprehensive Mental Health Action Plan 2013-2020, which builds upon the work of WHO's Mental Health Gap Action Programme. Within this programme, evidence-based guidelines for mental disorders were developed, including recommendations on appropriate use of medicines. Subsequently, the 67th World Health Assembly adopted a resolution on access to essential medicines, which urged Member States to improve national policies for the selection of essential medicines and to promote their availability, affordability and appropriate use. Following the precedent set by these important initiatives, this article presents eleven actions for improving access and appropriate use of psychotropic medicines. A 4 × 4 framework mapping actions as a function of the four components of access - selection, availability, affordability and appropriate use - and across four different health care levels, three of which belong to the supply side and one to the demand side, was developed. The actions are: developing a medicine selection process; promoting information and education activities for staff and end-users; developing a medicine regulation process; implementing a reliable supply system; implementing a reliable quality-control system; developing a community-based system of mental health care and promoting help-seeking behaviours; developing international agreements on medicine affordability; developing pricing policies and a sustainable financing system; developing or adopting evidence-based guidelines; monitoring the use of psychotropic medicines; promoting training initiatives for staff and end-users on critical appraisal of scientific evidence and appropriate use of psychotropic medicines. Activating these actions offers an unique opportunity to address the broader issue of increasing access to treatments and care for mental disorders, as current lack of attention to mental disorders is a central barrier across all domains of the 4 × 4 access framework.

The Salmonella In Silico Typing Resource (SISTR): An Open Web-Accessible Tool for Rapidly Typing and Subtyping Draft Salmonella Genome Assemblies.

PubMed

Yoshida, Catherine E; Kruczkiewicz, Peter; Laing, Chad R; Lingohr, Erika J; Gannon, Victor P J; Nash, John H E; Taboada, Eduardo N

2016-01-01

For nearly 100 years serotyping has been the gold standard for the identification of Salmonella serovars. Despite the increasing adoption of DNA-based subtyping approaches, serotype information remains a cornerstone in food safety and public health activities aimed at reducing the burden of salmonellosis. At the same time, recent advances in whole-genome sequencing (WGS) promise to revolutionize our ability to perform advanced pathogen characterization in support of improved source attribution and outbreak analysis. We present the Salmonella In Silico Typing Resource (SISTR), a bioinformatics platform for rapidly performing simultaneous in silico analyses for several leading subtyping methods on draft Salmonella genome assemblies. In addition to performing serovar prediction by genoserotyping, this resource integrates sequence-based typing analyses for: Multi-Locus Sequence Typing (MLST), ribosomal MLST (rMLST), and core genome MLST (cgMLST). We show how phylogenetic context from cgMLST analysis can supplement the genoserotyping analysis and increase the accuracy of in silico serovar prediction to over 94.6% on a dataset comprised of 4,188 finished genomes and WGS draft assemblies. In addition to allowing analysis of user-uploaded whole-genome assemblies, the SISTR platform incorporates a database comprising over 4,000 publicly available genomes, allowing users to place their isolates in a broader phylogenetic and epidemiological context. The resource incorporates several metadata driven visualizations to examine the phylogenetic, geospatial and temporal distribution of genome-sequenced isolates. As sequencing of Salmonella isolates at public health laboratories around the world becomes increasingly common, rapid in silico analysis of minimally processed draft genome assemblies provides a powerful approach for molecular epidemiology in support of public health investigations. Moreover, this type of integrated analysis using multiple sequence-based methods of sub-typing allows for continuity with historical serotyping data as we transition towards the increasing adoption of genomic analyses in epidemiology. The SISTR platform is freely available on the web at https://lfz.corefacility.ca/sistr-app/.

The Zooniverse

NASA Astrophysics Data System (ADS)

Borne, K. D.; Fortson, L.; Gay, P.; Lintott, C.; Raddick, M. J.; Wallin, J.

2009-12-01

The remarkable success of Galaxy Zoo as a citizen science project for galaxy classification within a terascale astronomy data collection has led to the development of a broader collaboration, known as the Zooniverse. Activities will include astronomy, lunar science, solar science, and digital humanities. Some features of our program include development of a unified framework for citizen science projects, development of a common set of user-based research tools, engagement of the machine learning community to apply machine learning algorithms on the rich training data provided by citizen scientists, and extension across multiple research disciplines. The Zooniverse collaboration is just getting started, but already we are implementing a scientifically deep follow-on to Galaxy Zoo. This project, tentatively named Galaxy Merger Zoo, will engage users in running numerical simulations, whose input parameter space is voluminous and therefore demands a clever solution, such as allowing the citizen scientists to select their own sets of parameters, which then trigger new simulations of colliding galaxies. The user interface design has many of the engaging features that retain users, including rapid feedback, visually appealing graphics, and the sense of playing a competitive game for the benefit of science. We will discuss these topics. In addition, we will also describe applications of Citizen Science that are being considered for the petascale science project LSST (Large Synoptic Survey Telescope). LSST will produce a scientific data system that consists of a massive image archive (nearly 100 petabytes) and a similarly massive scientific parameter database (20-40 petabytes). Applications of Citizen Science for such an enormous data collection will enable greater scientific return in at least two ways. First, citizen scientists work with real data and perform authentic research tasks of value to the advancement of the science, providing "human computation" capabilities and resources to review, annotate, and explore aspects of the data that are too overwhelming for the science team. Second, citizen scientists' inputs (in the form of rich training data and class labels) can be used to improve the classifiers that the project team uses to classify and prioritize new events detected in the petascale data stream. This talk will review these topics and provide an update on the Zooniverse project.

Shifting Practices Toward Recovery-Oriented Care Through an E-Recovery Portal in Community Mental Health Care: A Mixed-Methods Exploratory Study

PubMed Central

Strand, Monica; Eng, Lillian Sofie; Børøsund, Elin; Varsi, Cecilie; Ruland, Cornelia

2017-01-01

Background Mental health care is shifting from a primary focus on symptom reduction toward personal recovery-oriented care, especially for persons with long-term mental health care needs. Web-based portals may facilitate this shift, but little is known about how such tools are used or the role they may play in personal recovery. Objective The aim was to illustrate uses and experiences with the secure e-recovery portal “ReConnect” as an adjunct to ongoing community mental health care and explore its potential role in shifting practices toward recovery. Methods ReConnect was introduced into two Norwegian mental health care communities and used for 6 months. The aim was to support personal recovery and collaboration between service users and health care providers. Among inclusion criteria for participation were long-term care needs and at least one provider willing to interact with service users through ReConnect. The portal was designed to support ongoing collaboration as each service user-provider dyad/team found appropriate and consisted of (1) a toolbox of resources for articulating and working with recovery processes, such as status/goals/activities relative to life domains (eg, employment, social network, health), medications, network map, and exercises (eg, sleep hygiene, mindfulness); (2) messaging with providers who had partial access to toolbox content; and (3) a peer support forum. Quantitative data (ie, system log, questionnaires) were analyzed using descriptive statistics. Qualitative data (eg, focus groups, forum postings) are presented relative to four recovery-oriented practice domains: personally defined recovery, promoting citizenship, working relationships, and organizational commitment. Results Fifty-six participants (29 service users and 27 providers) made up 29 service user-provider dyads. Service users reported having 11 different mental health diagnoses, with a median 2 (range 1-7) diagnoses each. The 27 providers represented nine different professional backgrounds. The forum was the most frequently used module with 1870 visits and 542 postings. Service users’ control over toolbox resources (eg, defining and working toward personal goals), coupled with peer support, activated service users in their personal recovery processes and in community engagement. Some providers (30%, 8/27) did not interact with service users through ReConnect. Dyads that used the portal resources did so in highly diverse ways, and participants reported needing more than 6 months to discover and adapt optimal uses relative to their individual and collaborative needs. Conclusions Regardless of providers’ portal use, service users’ control over toolbox resources, coupled with peer support, offered an empowering common frame of reference that represented a shift toward recovery-oriented practices within communities. Although service users’ autonomous use of the portal can eventually influence providers in the direction of recovery practices, a fundamental shift is unlikely without broader organizational commitments aligned with recovery principles (eg, quantified goals for service user involvement in care plans). PMID:28465277

Activity Monitors as Support for Older Persons’ Physical Activity in Daily Life: Qualitative Study of the Users’ Experiences

PubMed Central

Eriksson, Lennie Carlén; Åkerberg, Nina; Johansson, Ann-Christin

2018-01-01

Background Falls are a major threat to the health and independence of seniors. Regular physical activity (PA) can prevent 40% of all fall injuries. The challenge is to motivate and support seniors to be physically active. Persuasive systems can constitute valuable support for persons aiming at establishing and maintaining healthy habits. However, these systems need to support effective behavior change techniques (BCTs) for increasing older adults’ PA and meet the senior users’ requirements and preferences. Therefore, involving users as codesigners of new systems can be fruitful. Prestudies of the user’s experience with similar solutions can facilitate future user-centered design of novel persuasive systems. Objective The aim of this study was to investigate how seniors experience using activity monitors (AMs) as support for PA in daily life. The addressed research questions are as follows: (1) What are the overall experiences of senior persons, of different age and balance function, in using wearable AMs in daily life?; (2) Which aspects did the users perceive relevant to make the measurements as meaningful and useful in the long-term perspective?; and (3) What needs and requirements did the users perceive as more relevant for the activity monitors to be useful in a long-term perspective? Methods This qualitative interview study included 8 community-dwelling older adults (median age: 83 years). The participants’ experiences in using two commercial AMs together with tablet-based apps for 9 days were investigated. Activity diaries during the usage and interviews after the usage were exploited to gather user experience. Comments in diaries were summarized, and interviews were analyzed by inductive content analysis. Results The users (n=8) perceived that, by using the AMs, their awareness of own PA had increased. However, the AMs’ impact on the users’ motivation for PA and activity behavior varied between participants. The diaries showed that self-estimated physical effort varied between participants and varied for each individual over time. Additionally, participants reported different types of accomplished activities; talking walks was most frequently reported. To be meaningful, measurements need to provide the user with a reliable receipt of whether his or her current activity behavior is sufficient for reaching an activity goal. Moreover, praise when reaching a goal was described as motivating feedback. To be useful, the devices must be easy to handle. In this study, the users perceived wearables as easy to handle, whereas tablets were perceived difficult to maneuver. Users reported in the diaries that the devices had been functional 78% (58/74) of the total test days. Conclusions Activity monitors can be valuable for supporting seniors’ PA. However, the potential of the solutions for a broader group of seniors can significantly be increased. Areas of improvement include reliability, usability, and content supporting effective BCTs with respect to increasing older adults’ PA. PMID:29391342

A Scientist's Guide to Achieving Broader Impacts through K–12 STEM Collaboration

PubMed Central

Komoroske, Lisa M.; Hameed, Sarah O.; Szoboszlai, Amber I.; Newsom, Amanda J.; Williams, Susan L.

2015-01-01

The National Science Foundation and other funding agencies are increasingly requiring broader impacts in grant applications to encourage US scientists to contribute to science education and society. Concurrently, national science education standards are using more inquiry-based learning (IBL) to increase students’ capacity for abstract, conceptual thinking applicable to real-world problems. Scientists are particularly well suited to engage in broader impacts via science inquiry outreach, because scientific research is inherently an inquiry-based process. We provide a practical guide to help scientists overcome obstacles that inhibit their engagement in K–12 IBL outreach and to attain the accrued benefits. Strategies to overcome these challenges include scaling outreach projects to the time available, building collaborations in which scientists’ research overlaps with curriculum, employing backward planning to target specific learning objectives, encouraging scientists to share their passion, as well as their expertise with students, and transforming institutional incentives to support scientists engaging in educational outreach. PMID:26955078

The Advanced Test Reactor National Scientific User Facility Advancing Nuclear Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

T. R. Allen; J. B. Benson; J. A. Foster

2009-05-01

To help ensure the long-term viability of nuclear energy through a robust and sustained research and development effort, the U.S. Department of Energy (DOE) designated the Advanced Test Reactor and associated post-irradiation examination facilities a National Scientific User Facility (ATR NSUF), allowing broader access to nuclear energy researchers. The mission of the ATR NSUF is to provide access to world-class nuclear research facilities, thereby facilitating the advancement of nuclear science and technology. The ATR NSUF seeks to create an engaged academic and industrial user community that routinely conducts reactor-based research. Cost free access to the ATR and PIE facilities ismore » granted based on technical merit to U.S. university-led experiment teams conducting non-proprietary research. Proposals are selected via independent technical peer review and relevance to DOE mission. Extensive publication of research results is expected as a condition for access. During FY 2008, the first full year of ATR NSUF operation, five university-led experiments were awarded access to the ATR and associated post-irradiation examination facilities. The ATR NSUF has awarded four new experiments in early FY 2009, and anticipates awarding additional experiments in the fall of 2009 as the results of the second 2009 proposal call. As the ATR NSUF program mature over the next two years, the capability to perform irradiation research of increasing complexity will become available. These capabilities include instrumented irradiation experiments and post-irradiation examinations on materials previously irradiated in U.S. reactor material test programs. The ATR critical facility will also be made available to researchers. An important component of the ATR NSUF an education program focused on the reactor-based tools available for resolving nuclear science and technology issues. The ATR NSUF provides education programs including a summer short course, internships, faculty-student team projects and faculty/staff exchanges. In June of 2008, the first week-long ATR NSUF Summer Session was attended by 68 students, university faculty and industry representatives. The Summer Session featured presentations by 19 technical experts from across the country and covered topics including irradiation damage mechanisms, degradation of reactor materials, LWR and gas reactor fuels, and non-destructive evaluation. High impact research results from leveraging the entire research infrastructure, including universities, industry, small business, and the national laboratories. To increase overall research capability, ATR NSUF seeks to form strategic partnerships with university facilities that add significant nuclear research capability to the ATR NSUF and are accessible to all ATR NSUF users. Current partner facilities include the MIT Reactor, the University of Michigan Irradiated Materials Testing Laboratory, the University of Wisconsin Characterization Laboratory, and the University of Nevada, Las Vegas transmission Electron Microscope User Facility. Needs for irradiation of material specimens at tightly controlled temperatures are being met by dedication of a large in-pile pressurized water loop facility for use by ATR NSUF users. Several environmental mechanical testing systems are under construction to determine crack growth rates and fracture toughness on irradiated test systems.« less

Unified User Interface to Support Effective and Intuitive Data Discovery, Dissemination, and Analysis at NASA GES DISC

NASA Technical Reports Server (NTRS)

Petrenko, M.; Hegde, M.; Bryant, K.; Johnson, J. E.; Ritrivi, A.; Shen, S.; Volmer, B.; Pham, L. B.

2015-01-01

Goddard Earth Sciences Data and Information Services Center (GES DISC) has been providing access to scientific data sets since 1990s. Beginning as one of the first Earth Observing System Data and Information System (EOSDIS) archive centers, GES DISC has evolved to offer a wide range of science-enabling services. With a growing understanding of needs and goals of its science users, GES DISC continues to improve and expand on its broad set of data discovery and access tools, sub-setting services, and visualization tools. Nonetheless, the multitude of the available tools, a partial overlap of functionality, and independent and uncoupled interfaces employed by these tools often leave the end users confused as of what tools or services are the most appropriate for a task at hand. As a result, some the services remain underutilized or largely unknown to the users, significantly reducing the availability of the data and leading to a great loss of scientific productivity. In order to improve the accessibility of GES DISC tools and services, we have designed and implemented UUI, the Unified User Interface. UUI seeks to provide a simple, unified, and intuitive one-stop shop experience for the key services available at GES DISC, including sub-setting (Simple Subset Wizard), granule file search (Mirador), plotting (Giovanni), and other services. In this poster, we will discuss the main lessons, obstacles, and insights encountered while designing the UUI experience. We will also present the architecture and technology behind UUI, including NodeJS, Angular, and Mongo DB, as well as speculate on the future of the tool at GES DISC as well as in a broader context of the Space Science Informatics.

Advantages of a Unified Earth and Space Science Approach for Geoscience Education: Perspectives from the National Center for Atmospheric Research

NASA Astrophysics Data System (ADS)

Johnson, R. M.; Barnes, T.; Bergman, J.; Carbone, L.; Eastburn, T.; Foster, S.; Gardiner, L.; Genyuk, J.; Henderson, S.; Lagrave, M.; Munoz, R.; Russell, R.; Araujo-Pradere, E.; Metcalfe, T.; Mastie, D.; Pennington, P.

2005-05-01

The intellectual divisions common among scientists involved in research in specific disciplines are frequently not shared by the broader community of learners. For example, in K-12 education, the Earth sciences and the space sciences have generally been taught in an integrated approach, until opportunities for more advanced courses become available at the higher grade levels in some fortunate school districts. When scientists involved in EPO activities retain a perspective limited to their particular science mission, rather than stepping back to a broader perspective that places the research in a larger context, they risk limiting the usefulness of these activities to a broad cross-section of learners that seek to learn in a contextual framework. The re-integration of Earth and space sciences within NASA's Science Mission Directorate provides an opportunity to more systematically take advantage of the fact that Earth is one of many examples of possible planetary evolution scenarios presented in our solar system and beyond. This development should encourage integration of research across the SMD into a broader context that encourages the development of higher learning skills and a systems thinking approach. At the National Center for Atmospheric Research, the interdisciplinary nature of the research problems we address requires an approach that integrates Earth and space science, and we parallel this in our education and outreach activities, ranging from our exhibits on climate change to our professional development workshops and online courses to our websites and curriculum development efforts. The Windows to the Universe project (http://www.windows.ucar.edu), initiated at the University of Michigan with support from NASA in 1995 and now developed and maintained at the University Corporation for Atmospheric Research, has maintained this integrated approach from its inception with great success - leading to over 6 million users of our English and Spanish language content, curriculum activities, and interactives from around the world in 2004. An exciting new web-based development interface utilizing templates and an image database allows scientists from around the world to collaborate with the Windows to the Universe team, becoming remote developers on the website. This approach has proven to work effectively for scientists eager to efficiently get their science research results out to the public, taking advantage of their specialized expertise and yet not requiring them to become specialists in informal or formal K-12 education.

Water use benefit index as a tool for community-based monitoring of water related trends in the Great Barrier Reef region

NASA Astrophysics Data System (ADS)

Smajgl, A.; Larson, S.; Hug, B.; De Freitas, D. M.

2010-12-01

SummaryThis paper presents a tool for documenting and monitoring water use benefits in the Great Barrier Reef catchments that allows temporal and spatial comparison along the region. Water, water use benefits and water allocations are currently receiving much attention from Australian policy makers and conservation practitioners. Because of the inherent complexity and variability in water quality, it is essential that scientific information is presented in a meaningful way to policy makers, managers and ultimately, to the general public who have to live with the consequences of the decisions. We developed an inexpensively populated and easily understandable water use benefit index as a tool for community-based monitoring of water related trends in the Great Barrier Reef region. The index is developed based on a comparative list of selected water-related indices integrating attributes across physico-chemical, economic, social, and ecological domains currently used in the assessment of water quality, water quantity and water use benefits in Australia. Our findings indicate that the proposed index allows the identification of water performance indicators by temporal and spatial comparisons. Benefits for decision makers and conservation practitioners include a flexible way of prioritization towards the domain with highest concern. The broader community benefits from a comprehensive and user-friendly tool, communicating changes in water quality trends more effectively.

WholeCellSimDB: a hybrid relational/HDF database for whole-cell model predictions.

PubMed

Karr, Jonathan R; Phillips, Nolan C; Covert, Markus W

2014-01-01

Mechanistic 'whole-cell' models are needed to develop a complete understanding of cell physiology. However, extracting biological insights from whole-cell models requires running and analyzing large numbers of simulations. We developed WholeCellSimDB, a database for organizing whole-cell simulations. WholeCellSimDB was designed to enable researchers to search simulation metadata to identify simulations for further analysis, and quickly slice and aggregate simulation results data. In addition, WholeCellSimDB enables users to share simulations with the broader research community. The database uses a hybrid relational/hierarchical data format architecture to efficiently store and retrieve both simulation setup metadata and results data. WholeCellSimDB provides a graphical Web-based interface to search, browse, plot and export simulations; a JavaScript Object Notation (JSON) Web service to retrieve data for Web-based visualizations; a command-line interface to deposit simulations; and a Python API to retrieve data for advanced analysis. Overall, we believe WholeCellSimDB will help researchers use whole-cell models to advance basic biological science and bioengineering. http://www.wholecellsimdb.org SOURCE CODE REPOSITORY: URL: http://github.com/CovertLab/WholeCellSimDB. © The Author(s) 2014. Published by Oxford University Press.

Ancillary Data Services of NASA's Planetary Data System

NASA Technical Reports Server (NTRS)

Acton, C.

1994-01-01

JPL's Navigation and Ancillary Information Facility (NAIF) has primary responsibility for design and implementation of the SPICE ancillary information system, supporting a wide range of space science mission design, observation planning and data analysis functions/activities. NAIF also serves as the geometry and ancillary data node of the Planetary Data System (PDS). As part of the PDS, NAIF archives SPICE and other ancillary data produced by flight projects. NAIF then distributes these data, and associated data access software and high-level tools, to researchers funded by NASA's Office of Space Science. Support for a broader user community is also offered to the extent resources permit. This paper describes the SPICE system and customer support offered by NAIF.

Play It, Learn It, Make It Last: Developing an Online Game to Create Self-Sufficient Library Information Users.

PubMed

Boyce, Lindsay M

2016-01-01

Library orientation at an academic health sciences library consisted of a five-minute overview within new student orientation. Past experience indicated this brief presentation was insufficient for students to learn about library resources. In 2014, an effort was made to supplement orientation by developing an online game aimed at enabling students to become self-sufficient through hands-on learning. A gaming model was chosen with expectations that competition and rewards would motivate students. Although the pilots suffered from low participation rates, the experience merits further research into the potential of a broader model of online library instruction in the health sciences environment.

Emissions Scenario Portal for Visualization of Low Carbon Pathways

NASA Astrophysics Data System (ADS)

Friedrich, J.; Hennig, R. J.; Mountford, H.; Altamirano, J. C.; Ge, M.; Fransen, T.

2016-12-01

This proposal for a presentation is centered around a new project which is developed collaboratively by the World Resources Institute (WRI), Google Inc., and Deep Decarbonization Pathways Project (DDPP). The project aims to develop an online, open portal, the Emissions Scenario Portal (ESP),to enable users to easily visualize a range of future greenhouse gas emission pathways linked to different scenarios of economic and energy developments, drawing from a variety of modeling tools. It is targeted to users who are not modelling experts, but instead policy analysts or advisors, investment analysts, and similar who draw on modelled scenarios to inform their work, and who can benefit from better access to, and transparency around, the wide range of emerging scenarios on ambitious climate action. The ESP will provide information from scenarios in a visually appealing and easy-to-understand manner that enable these users to recognize the opportunities to reduce GHG emissions, the implications of the different scenarios, and the underlying assumptions. To facilitate the application of the portal and tools in policy dialogues, a series of country-specific and potentially sector-specific workshops with key decision-makers and analysts, supported by relevant analysis, will be organized by the key partners and also in broader collaboration with others who might wish to convene relevant groups around the information. This project will provide opportunities for modelers to increase their outreach and visibility in the public space and to directly interact with key audiences of emissions scenarios, such as policy analysts and advisors. The information displayed on the portal will cover a wide range of indicators, sectors and important scenario characteristics such as macroeconomic information, emission factors and policy as well as technology assumptions in order to facilitate comparison. These indicators have been selected based on existing standards (such as the IIASA AR5 database, the Greenhouse Gas Protocol and accounting literature) and stakeholder consultations. Examples for use cases include: technical advisers for governments NGO/Civil Society advocates Investors and bankers Modelers and academics Business sustainability officers

Clinical user experiences of observation and response charts: focus group findings of using a new format chart incorporating a track and trigger system.

PubMed

Elliott, Doug; Allen, Emily; Perry, Lin; Fry, Margaret; Duffield, Christine; Gallagher, Robyn; Iedema, Rick; McKinley, Sharon; Roche, Michael

2015-01-01

Optimising clinical responses to deteriorating patients is an international indicator of acute healthcare quality. Observation charts incorporating track and trigger systems are an initiative to improve early identification and response to clinical deterioration. A suite of track and trigger 'Observation and Response Charts' were designed in Australia and initially tested in simulated environments. This paper reports initial clinical user experiences and views following implementation of these charts in adult general medical-surgical wards. Across eight trial sites, 44 focus groups were conducted with 218 clinical ward staff, mostly nurses, who received training and had used the charts in routine clinical practice for the preceding 2-6 weeks. Transcripts of audio recordings were analysed for emergent themes using an inductive approach. In this exploration of initial user experiences, key emergent themes were: tensions between vital sign 'ranges versus precision' to support decision making; using a standardised 'generalist chart in a range of specialist practice' areas; issues of 'clinical credibility', 'professional autonomy' and 'influences of doctors' when communicating abnormal signs; and 'permission and autonomy' when escalating care according to the protocol. Across themes, participants presented a range of positive, negative or mixed views. Benefits were identified despite charts not always being used up to their optimal design function. Participants reported tensions between chart objectives and clinical practices, revealing mismatches between design characteristics and human staff experiences. Overall, an initial view of 'increased activity/uncertain benefit' was uncovered. Findings particularly reinforced the significant influences of organisational work-based cultures, disciplinary boundaries and interdisciplinary communication on implementation of this new practice chart. Optimal use of all chart design characteristics will be possible when these broader cultural issues are addressed. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Teaching Hyporheic and Groundwater Flow Concepts Using an Interactive Computer Simulation

NASA Astrophysics Data System (ADS)

Stonedahl, S. H.; Stonedahl, F.

2016-12-01

We built an educational flow simulator with an interactive web-based interface that allows students to investigate the effects of arbitrary head functions on water flowing through various configurations of permeable/impermeable sediments. The domain consists of a 24 by 48 rectangular grid of sediments with no-flow bottom and side boundaries and a constant head surface water-groundwater (SWGW) interface boundary. The SWGW interface head function can be drawn freehand with the mouse or specified to be a step function, a sine curve, or a zig-zag function, where the amplitude and wavenumber parameters of the head functions are chosen by the user. The subsurface domain may be modified by drawing no-flow (impermeable) barriers in the sediment, changing any number of the 1152 grid cells into no flow cells. The program iteratively solves the Laplace equation to calculate head values at each grid cell within the sediment. Users can then start water particles along the SWGW interface and track their paths through the system to visualize the head-induced flow. Sediment cells can be color coded by head values or water speed. Exploring these systems with the simulator allows users to improve their understanding of the relationship between head and velocity as well as how the position of no-flow barriers impacts water flow in saturated sediments. These learning objectives are amenable to our target audience of undergraduate students, but younger (middle/high school) students may also be able to absorb key concepts by playing with the simulation. The structure of the simulation itself highlights the broader idea of simulation of natural processes through the discretization of continuous environments. The simulation was developed using the NetLogo platform and runs embedded in a webpage: http://susa.stonedahl.com/swgwsimulator. The simulation source code is available and can readily be modified by other educators (or students) to create additional features and options.

NAP: The Network Analysis Profiler, a web tool for easier topological analysis and comparison of medium-scale biological networks.

PubMed

Theodosiou, Theodosios; Efstathiou, Georgios; Papanikolaou, Nikolas; Kyrpides, Nikos C; Bagos, Pantelis G; Iliopoulos, Ioannis; Pavlopoulos, Georgios A

2017-07-14

Nowadays, due to the technological advances of high-throughput techniques, Systems Biology has seen a tremendous growth of data generation. With network analysis, looking at biological systems at a higher level in order to better understand a system, its topology and the relationships between its components is of a great importance. Gene expression, signal transduction, protein/chemical interactions, biomedical literature co-occurrences, are few of the examples captured in biological network representations where nodes represent certain bioentities and edges represent the connections between them. Today, many tools for network visualization and analysis are available. Nevertheless, most of them are standalone applications that often (i) burden users with computing and calculation time depending on the network's size and (ii) focus on handling, editing and exploring a network interactively. While such functionality is of great importance, limited efforts have been made towards the comparison of the topological analysis of multiple networks. Network Analysis Provider (NAP) is a comprehensive web tool to automate network profiling and intra/inter-network topology comparison. It is designed to bridge the gap between network analysis, statistics, graph theory and partially visualization in a user-friendly way. It is freely available and aims to become a very appealing tool for the broader community. It hosts a great plethora of topological analysis methods such as node and edge rankings. Few of its powerful characteristics are: its ability to enable easy profile comparisons across multiple networks, find their intersection and provide users with simplified, high quality plots of any of the offered topological characteristics against any other within the same network. It is written in R and Shiny, it is based on the igraph library and it is able to handle medium-scale weighted/unweighted, directed/undirected and bipartite graphs. NAP is available at http://bioinformatics.med.uoc.gr/NAP .

The impact and societal benefits of using earth observation for ground water policies in the agricultural sector

NASA Astrophysics Data System (ADS)

Pearlman, Francoise; Bernknopf, Richard; Pearlman, Jay; Rigby, Michael

2017-04-01

Assessment of the impact and societal benefit of Earth Observation (EO) is a multidisciplinary task that involves the social, economic and environmental knowledge to formulate indicators and methods. The value of information (VOI) of EO is based on case studies that document the value in use of the information in a specific decision. A case study is an empirical inquiry investigating a phenomenon. It emphasizes detailed contextual analysis of a limited number of events or conditions and their relationships. Quantitative estimates of the benefits and costs of the geospatial information derived from EO data document and demonstrate its economic value. A case study was completed to examine some of the technical perspectives of adapting and coupling satellite imagery and in situ water quality measurements to forecast changes in groundwater quality in the agricultural sector in Iowa. The analysis was conducted to identify the ability of EO to assist in improving agricultural land management and regulation of balancing production and groundwater contamination. The Iowa case study described the application of Landsat data in a land adaptation strategy to maintain agricultural production and groundwater water quality. Results demonstrated that Landsat information facilitates spatiotemporal analysis of the impact of nitrates (fertilizer application) on groundwater resources and that crop production could be retained while groundwater quality is maintained. To transition to the operational use of the geospatial information, the Landsat data should be applied in a use case where Interaction of various stakeholders within a decision process are addressed. The objective is to design implementation experiments of a system from the user's and contributor's perspective, and to communicate system behavior in their terms. A use case requires communication of system requirements, how the system operates and may be used, the roles that all participants play and what value the user will receive from the system. The use case must be broader than simply a technical demonstration of capability and involves scientific experts, farmers and their representatives, and the Government. Decisions will ultimately need to take into account some level of uncertainty in the scientific "measurement". The data also have statistical variability which affects the confidence in the value of information. These issues are concerns when implementing remote sensing technology and must be examined from an end user perspective and their impact discussed and understood. The study team held meetings with subject experts from Iowa State University and the Iowa Farm Bureau to explore the next steps in developing the use case. A meeting between the study team and the Iowa Farm Bureau centered on the need for efficient regulation of land use and regulation of agrochemical application in the Midwest. This presentation will describe the results of the case study and the ongoing investigation into directions into the broader application of the use case and the application of economic indicators that have applications across fields of interest.

Beyond NIMBYism: understanding community antipathy toward needle distribution services.

PubMed

Davidson, Peter J; Howe, Mary

2014-05-01

In late 2007 the Homeless Youth Alliance (HYA), a small non-profit serving homeless youth in the Haight-Ashbury neighbourhood of San Francisco, USA, attempted to move its needle exchange service from a site on the Haight street commercial strip to a community centre approximately 150m away. The reaction of the housed community in the area was vocal and organized, and attracted considerable regional media attention. Ultimately, the plan to move the service had to be cancelled. The authors were, respectively, board chair and executive director of HYA at the time, and collected extensive field notes and media records as events unfolded. In this paper, we re-examine these events through literatures on contested spaces and on 'Not In My Backyard' (NIMBY) resistance to social services. We found that opposition to the service relocation had little to do with opposition to needle exchange itself, but rather was symptomatic of broader contestation over the identity and character of the neighbourhood. On the one hand, the neighbourhood had experienced skyrocketing housing prices over the past 40 years, making home ownership almost exclusively the province of the wealthy. On the other, the neighbourhood retains historic connections to the 1968 'Summer of Love', and the main commercial strip forms the centre of an active injecting drug use scene. As a consequence, many home owners who felt they had made considerable sacrifices to afford to live in the area expressed a sense of being "under siege" from drug users, and also believed that the City government pursues a deliberate policy of "keeping the Haight weird" by supporting ongoing service provision to drug users in the area. Housed residents responded to this situation in a variety of ways. One response was to engage in what we term 'defensive place making', in which a small part of a broader neighbourhood is reimagined as "a different neighbourhood". HYA's attempt to move from its current location to this 'different neighbourhood' was thus perceived as an "invasion" which threatened to break down a tentatively established separate identity. We conclude with a discussion of the relevance of these events for understanding and mitigating community opposition to services for drug users elsewhere. Copyright © 2013 Elsevier B.V. All rights reserved.

Beyond NIMBYism: Understanding community antipathy toward needle distribution services

PubMed Central

Davidson, Peter J.; Howe, Mary

2014-01-01

In late 2007 the Homeless Youth Alliance (HYA), a small non-profit serving homeless youth in the Haight-Ashbury neighbourhood of San Francisco, USA, attempted to move its needle exchange service from a site on the Haight street commercial strip to a community centre approximately 150 m away. The reaction of the housed community in the area was vocal and organized, and attracted considerable regional media attention. Ultimately, the plan to move the service had to be cancelled. The authors were, respectively, board chair and executive director of HYA at the time, and collected extensive field notes and media records as events unfolded. In this paper, we re-examine these events through literatures on contested spaces and on ‘Not In My Backyard’ (NIMBY) resistance to social services. We found that opposition to the service relocation had little to do with opposition to needle exchange itself, but rather was symptomatic of broader contestation over the identity and character of the neighbourhood. On the one hand, the neighbourhood had experienced skyrocketing housing prices over the past 40 years, making home ownership almost exclusively the province of the wealthy. On the other, the neighbourhood retains historic connections to the 1968 ‘Summer of Love’, and the main commercial strip forms the centre of an active injecting drug use scene. As a consequence, many home owners who felt they had made considerable sacrifices to afford to live in the area expressed a sense of being “under siege” from drug users, and also believed that the City government pursues a deliberate policy of “keeping the Haight weird” by supporting ongoing service provision to drug users in the area. Housed residents responded to this situation in a variety of ways. One response was to engage in what we term ‘defensive place making’, in which a small part of a broader neighbourhood is reimagined as “a different neighbourhood”. HYA’s attempt to move from its current location to this ‘different neighbourhood’ was thus perceived as an “invasion” which threatened to break down a tentatively established separate identity. We conclude with a discussion of the relevance of these events for understanding and mitigating community opposition to services for drug users elsewhere. PMID:24309432

The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study.

PubMed

Altmaier, Elisabeth; Menni, Cristina; Heier, Margit; Meisinger, Christa; Thorand, Barbara; Quell, Jan; Kobl, Michael; Römisch-Margl, Werner; Valdes, Ana M; Mangino, Massimo; Waldenberger, Melanie; Strauch, Konstantin; Illig, Thomas; Adamski, Jerzy; Spector, Tim; Gieger, Christian; Suhre, Karsten; Kastenmüller, Gabi

2016-01-01

Angiotensin-I-converting enzyme (ACE) inhibitors are an important class of antihypertensives whose action on the human organism is still not fully understood. Although it is known that ACE especially cleaves COOH-terminal dipeptides from active polypeptides, the whole range of substrates and products is still unknown. When analyzing the action of ACE inhibitors, effects of genetic variation on metabolism need to be considered since genetic variance in the ACE gene locus was found to be associated with ACE-concentration in blood as well as with changes in the metabolic profiles of a general population. To investigate the interactions between genetic variance at the ACE-locus and the influence of ACE-therapy on the metabolic status we analyzed 517 metabolites in 1,361 participants from the KORA F4 study. We replicated our results in 1,964 individuals from TwinsUK. We observed differences in the concentration of five dipeptides and three ratios of di- and oligopeptides between ACE inhibitor users and non-users that were genotype dependent. Such changes in the concentration affected major homozygotes, and to a lesser extent heterozygotes, while minor homozygotes showed no or only small changes in the metabolite status. Two of these resulting dipeptides, namely aspartylphenylalanine and phenylalanylserine, showed significant associations with blood pressure which qualifies them-and perhaps also the other dipeptides-as readouts of ACE-activity. Since so far ACE activity measurement is substrate specific due to the usage of only one oligopeptide, taking several dipeptides as potential products of ACE into account may provide a broader picture of the ACE activity.

Social context, diversity and risk among women who inject drugs in Vietnam: descriptive findings from a cross-sectional survey.

PubMed

Khuat, Oanh T H; Morrow, Martha; Nguyen, Trang N N; Armstrong, Gregory

2015-10-16

Women who inject drugs (WWID) are neglected globally in research and programming yet may be likelier than males to practise sexual and injecting risks and be infected with HIV and more stigmatised but seek fewer services. Little is known about characteristics, practices and nexus between drugs and sex work of WWID in Vietnam, where unsafe injecting has driven HIV transmission, and commercial sex and inconsistent condom use are prevalent. This was the first quantitative investigation of Vietnamese WWID recruited as injecting drug users. This article summarises descriptive findings. A cross-sectional survey was conducted among WWID in Hanoi (n = 203) and Ho Chi Minh City (HCMC) (n = 200) recruited using respondent-driven sampling. Characteristics varied within and between sites. Twenty-two percent in Hanoi and 47.5 % in HCMC had never sold sex. Almost all commenced with smoking heroin, some as children. Most injected frequently, usually alone, although 8 % (Hanoi) and 18 % (HCMC) shared equipment in the previous month. Some had sex--and sold it--as children; most had multiple partners. Condom use was high with clients but very low with intimate partners, often injecting drug users. HIV knowledge was uneven, and large minorities were not tested recently (or ever) for HIV. Nearly all perceived intense gender-related stigma, especially for drug use. This ground-breaking study challenges assumptions about characteristics and risks based on anecdotal evidence and studies among men. Most WWID were vulnerable to sexual HIV transmission from intimate partners. Interventions should incorporate broader sociocultural context to protect this highly stigmatised population.

Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Potter, Jennifer; Cappers, Peter

The Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs research describe a variety of DR opportunities and the various bulk power system services they can provide. The bulk power system services are mapped to a generalized taxonomy of DR “service types”, which allows us to discuss DR opportunities and bulk power system services in fewer yet broader categories that share similar technological requirements which mainly drive DR enablement costs. The research presents a framework for the costs to automate DR and provides descriptions of the various elements that drive enablement costs. The report introduces the various DRmore » enabling technologies and end-uses, identifies the various services that each can provide to the grid and provides the cost assessment for each enabling technology. In addition to a report, this research includes a Demand Response Advanced Controls Database and User Manual. They are intended to provide users with the data that underlies this research and instructions for how to use that database more effectively and efficiently.« less

Improving data discoverability, accessibility, and interoperability with the Esri ArcGIS Platform at the NASA Atmospheric Science Data Center (ASDC).

NASA Astrophysics Data System (ADS)

Tisdale, M.

2017-12-01

NASA's Atmospheric Science Data Center (ASDC) is operationally using the Esri ArcGIS Platform to improve data discoverability, accessibility and interoperability to meet the diversifying user requirements from government, private, public and academic communities. The ASDC is actively working to provide their mission essential datasets as ArcGIS Image Services, Open Geospatial Consortium (OGC) Web Mapping Services (WMS), and OGC Web Coverage Services (WCS) while leveraging the ArcGIS multidimensional mosaic dataset structure. Science teams at ASDC are utilizing these services through the development of applications using the Web AppBuilder for ArcGIS and the ArcGIS API for Javascript. These services provide greater exposure of ASDC data holdings to the GIS community and allow for broader sharing and distribution to various end users. These capabilities provide interactive visualization tools and improved geospatial analytical tools for a mission critical understanding in the areas of the earth's radiation budget, clouds, aerosols, and tropospheric chemistry. The presentation will cover how the ASDC is developing geospatial web services and applications to improve data discoverability, accessibility, and interoperability.

User Experience Evaluation Methods in Product Development (UXEM'09)

NASA Astrophysics Data System (ADS)

Roto, Virpi; Väänänen-Vainio-Mattila, Kaisa; Law, Effie; Vermeeren, Arnold

High quality user experience (UX) has become a central competitive factor of product development in mature consumer markets [1]. Although the term UX originated from industry and is a widely used term also in academia, the tools for managing UX in product development are still inadequate. A prerequisite for designing delightful UX in an industrial setting is to understand both the requirements tied to the pragmatic level of functionality and interaction and the requirements pertaining to the hedonic level of personal human needs, which motivate product use [2]. Understanding these requirements helps managers set UX targets for product development. The next phase in a good user-centered design process is to iteratively design and evaluate prototypes [3]. Evaluation is critical for systematically improving UX. In many approaches to UX, evaluation basically needs to be postponed until the product is fully or at least almost fully functional. However, in an industrial setting, it is very expensive to find the UX failures only at this phase of product development. Thus, product development managers and developers have a strong need to conduct UX evaluation as early as possible, well before all the parts affecting the holistic experience are available. Different types of products require evaluation on different granularity and maturity levels of a prototype. For example, due to its multi-user characteristic, a community service or an enterprise resource planning system requires a broader scope of UX evaluation than a microwave oven or a word processor that is meant for a single user at a time. Before systematic UX evaluation can be taken into practice, practical, lightweight UX evaluation methods suitable for different types of products and different phases of product readiness are needed. A considerable amount of UX research is still about the conceptual frameworks and models for user experience [4]. Besides, applying existing usability evaluation methods (UEMs) without adaptation to evaluate UX may lead to some scoping issues. Consequently, there is a strong need to put UX evaluation from research into practice.

Dose effect of patient-care team communication via secure portal messaging on glucose and blood pressure control.

PubMed

Price-Haywood, Eboni G; Luo, Qingyang; Monlezun, Dominique

2018-02-09

Organizational strategies for implementing eHealth tools influence patient and provider use of portal technology. This study examines whether the intensity of bidirectional secure portal messaging is associated with improved clinical outcomes. This is a retrospective cohort analysis of 101 019 patients with diabetes or hypertension (11 138 active portal users) who received primary care within the Ochsner Health System between 2012 and 2014. Propensity score-adjusted multivariable fixed effects regression panel analysis was used to examine associations between intensity of "medical advice" portal messaging and glucose/blood pressure control. Most portal users rarely used medical advice messaging. A higher proportion of patients who were age 50 years and older, female, white non-Hispanic, and with co-morbid diabetes and hypertension had higher frequency and intensity of medical advice messaging. Study findings revealed a dose-response effect of the intensity of messaging on glucose control, whereby, compared to nonportal users, each level of messaging among portal users was associated with greater decreases in HbA1c (β estimate [95% CI]: none -0.28 (-0.34 to -0.22); low -0.28 (-0.32 to -0.24); medium -0.41 (-0.52 to -0.31); high -0.43 (-0.60 to -0.27), all P ≤ .001). There was no observed effect on blood pressure. The digital divide exists not only between portal users and nonusers but also among portal users. Research exploring the relationship between intensity of bidirectional secure messaging and health outcomes for a broader scope of chronic conditions is needed. Future implementation research must also elucidate best practices that enhance not only the use of portals by patients and providers, but how they use portals. © The Author(s) 2018. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Considerations that will determine if competency-based assessment is a sustainable innovation.

PubMed

Dauphinee, W Dale; Boulet, John R; Norcini, John J

2018-05-18

Educational assessment for the health professions has seen a major attempt to introduce competency based frameworks. As high level policy developments, the changes were intended to improve outcomes by supporting learning and skills development. However, we argue that previous experiences with major innovations in assessment offer an important road map for developing and refining assessment innovations, including careful piloting and analyses of their measurement qualities and impacts. Based on the literature, numerous assessment workshops, personal interactions with potential users, and our 40 years of experience in implementing assessment change, we lament the lack of a coordinated approach to clarify and improve measurement qualities and functionality of competency based assessment (CBA). To address this worrisome situation, we offer two roadmaps to guide CBA's further development. Initially, reframe and address CBA as a measurement development opportunity. Secondly, using a roadmap adapted from the management literature on sustainable innovation, the medical assessment community needs to initiate an integrated plan to implement CBA as a sustainable innovation within existing educational programs and self-regulatory enterprises. Further examples of down-stream opportunities to refocus CBA at the implementation level within faculties and within the regulatory framework of the profession are offered. In closing, we challenge the broader assessment community in medicine to step forward and own the challenge and opportunities to reframe CBA as an innovation to improve the quality of the clinical educational experience. The goal is to optimize assessment in health education and ultimately improve the public's health.

SNPnexus: assessing the functional relevance of genetic variation to facilitate the promise of precision medicine.

PubMed

Dayem Ullah, Abu Z; Oscanoa, Jorge; Wang, Jun; Nagano, Ai; Lemoine, Nicholas R; Chelala, Claude

2018-05-11

Broader functional annotation of genetic variation is a valuable means for prioritising phenotypically-important variants in further disease studies and large-scale genotyping projects. We developed SNPnexus to meet this need by assessing the potential significance of known and novel SNPs on the major transcriptome, proteome, regulatory and structural variation models. Since its previous release in 2012, we have made significant improvements to the annotation categories and updated the query and data viewing systems. The most notable changes include broader functional annotation of noncoding variants and expanding annotations to the most recent human genome assembly GRCh38/hg38. SNPnexus has now integrated rich resources from ENCODE and Roadmap Epigenomics Consortium to map and annotate the noncoding variants onto different classes of regulatory regions and noncoding RNAs as well as providing their predicted functional impact from eight popular non-coding variant scoring algorithms and computational methods. A novel functionality offered now is the support for neo-epitope predictions from leading tools to facilitate its use in immunotherapeutic applications. These updates to SNPnexus are in preparation for its future expansion towards a fully comprehensive computational workflow for disease-associated variant prioritization from sequencing data, placing its users at the forefront of translational research. SNPnexus is freely available at http://www.snp-nexus.org.

Proposed Array-based Deep Space Network for NASA

NASA Technical Reports Server (NTRS)

Bagri, Durgadas S.; Statman, Joseph I.; Gatti, Mark S.

2007-01-01

The current assets of the Deep Space Network (DSN) of the National Aeronautics and Space Administration (NASA), especially the 70-m antennas, are aging and becoming less reliable. Furthermore, they are expensive to operate and difficult to upgrade for operation at Ka-band (321 GHz). Replacing them with comparable monolithic large antennas would be expensive. On the other hand, implementation of similar high-sensitivity assets can be achieved economically using an array-based architecture, where sensitivity is measured by G/T, the ratio of antenna gain to system temperature. An array-based architecture would also provide flexibility in operations and allow for easy addition of more G/T whenever required. Therefore, an array-based plan of the next-generation DSN for NASA has been proposed. The DSN array would provide more flexible downlink capability compared to the current DSN for robust telemetry, tracking and command services to the space missions of NASA and its international partners in a cost effective way. Instead of using the array as an element of the DSN and relying on the existing concept of operation, we explore a broader departure in establishing a more modern concept of operations to reduce the operations costs. This paper presents the array-based architecture for the next generation DSN. It includes system block diagram, operations philosophy, user's view of operations, operations management, and logistics like maintenance philosophy and anomaly analysis and reporting. To develop the various required technologies and understand the logistics of building the array-based lowcost system, a breadboard array of three antennas has been built. This paper briefly describes the breadboard array system and its performance.

Can broader diffusion of value-based insurance design increase benefits from US health care without increasing costs? Evidence from a computer simulation model.

PubMed

Braithwaite, R Scott; Omokaro, Cynthia; Justice, Amy C; Nucifora, Kimberly; Roberts, Mark S

2010-02-16

Evidence suggests that cost sharing (i.e.,copayments and deductibles) decreases health expenditures but also reduces essential care. Value-based insurance design (VBID) has been proposed to encourage essential care while controlling health expenditures. Our objective was to estimate the impact of broader diffusion of VBID on US health care benefits and costs. We used a published computer simulation of costs and life expectancy gains from US health care to estimate the impact of broader diffusion of VBID. Two scenarios were analyzed: (1) applying VBID solely to pharmacy benefits and (2) applying VBID to both pharmacy benefits and other health care services (e.g., devices). We assumed that cost sharing would be eliminated for high-value services (<$100,000 per life-year), would remain unchanged for intermediate- or unknown-value services ($100,000-$300,000 per life-year or unknown), and would be increased for low-value services (>$300,000 per life-year). All costs are provided in 2003 US dollars. Our simulation estimated that approximately 60% of health expenditures in the US are spent on low-value services, 20% are spent on intermediate-value services, and 20% are spent on high-value services. Correspondingly, the vast majority (80%) of health expenditures would have cost sharing that is impacted by VBID. With prevailing patterns of cost sharing, health care conferred 4.70 life-years at a per-capita annual expenditure of US$5,688. Broader diffusion of VBID to pharmaceuticals increased the benefit conferred by health care by 0.03 to 0.05 additional life-years, without increasing costs and without increasing out-of-pocket payments. Broader diffusion of VBID to other health care services could increase the benefit conferred by health care by 0.24 to 0.44 additional life-years, also without increasing costs and without increasing overall out-of-pocket payments. Among those without health insurance, using cost saving from VBID to subsidize insurance coverage would increase the benefit conferred by health care by 1.21 life-years, a 31% increase. Broader diffusion of VBID may amplify benefits from US health care without increasing health expenditures.

CET exSim: mineral exploration experience via simulation

NASA Astrophysics Data System (ADS)

Wong, Jason C.; Holden, Eun-Jung; Kovesi, Peter; McCuaig, T. Campbell; Hronsky, Jon

2013-08-01

Undercover mineral exploration is a challenging task as it requires understanding of subsurface geology by relying heavily on remotely sensed (i.e. geophysical) data. Cost-effective exploration is essential in order to increase the chance of success using finite budgets. This requires effective decision-making in both the process of selecting the optimum data collection methods and in the process of achieving accuracy during subsequent interpretation. Traditionally, developing the skills, behaviour and practices of exploration decision-making requires many years of experience through working on exploration projects under various geological settings, commodities and levels of available resources. This implies long periods of sub-optimal exploration decision-making, before the necessary experience has been successfully obtained. To address this critical industry issue, our ongoing research focuses on the development of the unique and novel e-learning environment, exSim, which simulates exploration scenarios where users can test their strategies and learn the consequences of their choices. This simulator provides an engaging platform for self-learning and experimentation in exploration decision strategies, providing a means to build experience more effectively. The exSim environment also provides a unique platform on which numerous scenarios and situations (e.g. deposit styles) can be simulated, potentially allowing the user to become virtually familiarised with a broader scope of exploration practices. Harnessing the power of computer simulation, visualisation and an intuitive graphical user interface, the simulator provides a way to assess the user's exploration decisions and subsequent interpretations. In this paper, we present the prototype functionalities in exSim including: simulation of geophysical surveys, follow-up drill testing and interpretation assistive tools.

ESIP Information Quality Cluster (IQC)

NASA Technical Reports Server (NTRS)

Ramapriyan, H. K.; Peng, Ge; Moroni, David F.

2016-01-01

The Information Quality Cluster (IQC) within the Federation of Earth Science Information Partners (ESIP) was initially formed in 2011 and has evolved significantly over time. The current objectives of the IQC are to: 1. Actively evaluate community data quality best practices and standards; 2. Improve capture, description, discovery, and usability of information about data quality in Earth science data products; 3. Ensure producers of data products are aware of standards and best practices for conveying data quality, and data providers distributors intermediaries establish, improve and evolve mechanisms to assist users in discovering and understanding data quality information; and 4. Consistently provide guidance to data managers and stewards on how best to implement data quality standards and best practices to ensure and improve maturity of their data products. The activities of the IQC include: 1. Identification of additional needs for consistently capturing, describing, and conveying quality information through use case studies with broad and diverse applications; 2. Establishing and providing community-wide guidance on roles and responsibilities of key players and stakeholders including users and management; 3. Prototyping of conveying quality information to users in a more consistent, transparent, and digestible manner; 4. Establishing a baseline of standards and best practices for data quality; 5. Evaluating recommendations from NASA's DQWG in a broader context and proposing possible implementations; and 6. Engaging data providers, data managers, and data user communities as resources to improve our standards and best practices. Following the principles of openness of the ESIP Federation, IQC invites all individuals interested in improving capture, description, discovery, and usability of information about data quality in Earth science data products to participate in its activities.

New Web Services for Broader Access to National Deep Submergence Facility Data Resources Through the Interdisciplinary Earth Data Alliance

NASA Astrophysics Data System (ADS)

Ferrini, V. L.; Grange, B.; Morton, J. J.; Soule, S. A.; Carbotte, S. M.; Lehnert, K.

2016-12-01

The National Deep Submergence Facility (NDSF) operates the Human Occupied Vehicle (HOV) Alvin, the Remotely Operated Vehicle (ROV) Jason, and the Autonomous Underwater Vehicle (AUV) Sentry. These vehicles are deployed throughout the global oceans to acquire sensor data and physical samples for a variety of interdisciplinary science programs. As part of the EarthCube Integrative Activity Alliance Testbed Project (ATP), new web services were developed to improve access to existing online NDSF data and metadata resources. These services make use of tools and infrastructure developed by the Interdisciplinary Earth Data Alliance (IEDA) and enable programmatic access to metadata and data resources as well as the development of new service-driven user interfaces. The Alvin Frame Grabber and Jason Virtual Van enable the exploration of frame-grabbed images derived from video cameras on NDSF dives. Metadata available for each image includes time and vehicle position, data from environmental sensors, and scientist-generated annotations, and data are organized and accessible by cruise and/or dive. A new FrameGrabber web service and service-driven user interface were deployed to offer integrated access to these data resources through a single API and allows users to search across content curated in both systems. In addition, a new NDSF Dive Metadata web service and service-driven user interface was deployed to provide consolidated access to basic information about each NDSF dive (e.g. vehicle name, dive ID, location, etc), which is important for linking distributed data resources curated in different data systems.

Systematic review of studies evaluating the broader economic impact of vaccination in low and middle income countries.

PubMed

Deogaonkar, Rohan; Hutubessy, Raymond; van der Putten, Inge; Evers, Silvia; Jit, Mark

2012-10-16

Most health economic evaluations of childhood vaccination only capture the health and short-term economic benefits. Measuring broader, long-term effects of vaccination on productivity and externalities could provide a more complete picture of the value of vaccines. MEDLINE, EconLit and NHS-EED databases were searched for articles published between January 1990 and July 2011, which captured broader economic benefits of vaccines in low and middle income countries. Studies were included if they captured at least one of the following categories on broader economic impact: outcome-related productivity gains, behaviour-related productivity gains, ecological externalities, equity gains, financial sustainability gains or macroeconomic benefits. Twenty-six relevant studies were found, including observational studies, economic models and contingent valuation studies. Of the identified broader impacts, outcome-related productivity gains and ecological externalities were most commonly accounted for. No studies captured behaviour-related productivity gains or macroeconomic effects. There was some evidence to show that vaccinated children 8-14 years of age benefit from increased cognitive ability. Productivity loss due to morbidity and mortality was generally measured using the human capital approach. When included, herd immunity effects were functions of coverage rates or based on reduction in disease outcomes. External effects of vaccines were observed in terms of equitable health outcomes and contribution towards synergistic and financially sustainable healthcare programs. Despite substantial variation in the methods of measurement and outcomes used, the inclusion of broader economic impact was found to improve the attractiveness of vaccination. Further research is needed on how different tools and techniques can be used in combination to capture the broader impact of vaccination in a way that is consistent with other health economic evaluations. In addition, more country level evidence is needed from low and middle income countries to justify future investments in vaccines and immunization programs. Finally, the proposed broader economic impact framework may contribute towards better communication of the economic arguments surrounding vaccine uptake, leading to investments in immunization by stakeholders outside of the traditional health care sector such as ministries of finance and national treasuries.

Systematic review of studies evaluating the broader economic impact of vaccination in low and middle income countries

PubMed Central

2012-01-01

Background Most health economic evaluations of childhood vaccination only capture the health and short-term economic benefits. Measuring broader, long-term effects of vaccination on productivity and externalities could provide a more complete picture of the value of vaccines. Method MEDLINE, EconLit and NHS-EED databases were searched for articles published between January 1990 and July 2011, which captured broader economic benefits of vaccines in low and middle income countries. Studies were included if they captured at least one of the following categories on broader economic impact: outcome-related productivity gains, behaviour-related productivity gains, ecological externalities, equity gains, financial sustainability gains or macroeconomic benefits. Results Twenty-six relevant studies were found, including observational studies, economic models and contingent valuation studies. Of the identified broader impacts, outcome-related productivity gains and ecological externalities were most commonly accounted for. No studies captured behaviour-related productivity gains or macroeconomic effects. There was some evidence to show that vaccinated children 8–14 years of age benefit from increased cognitive ability. Productivity loss due to morbidity and mortality was generally measured using the human capital approach. When included, herd immunity effects were functions of coverage rates or based on reduction in disease outcomes. External effects of vaccines were observed in terms of equitable health outcomes and contribution towards synergistic and financially sustainable healthcare programs. Conclusion Despite substantial variation in the methods of measurement and outcomes used, the inclusion of broader economic impact was found to improve the attractiveness of vaccination. Further research is needed on how different tools and techniques can be used in combination to capture the broader impact of vaccination in a way that is consistent with other health economic evaluations. In addition, more country level evidence is needed from low and middle income countries to justify future investments in vaccines and immunization programs. Finally, the proposed broader economic impact framework may contribute towards better communication of the economic arguments surrounding vaccine uptake, leading to investments in immunization by stakeholders outside of the traditional health care sector such as ministries of finance and national treasuries. PMID:23072714

Outreach, Diversity, and Education Supported by NSF Facilities LacCore and the Continental Scientific Drilling Coordination Office (CSDCO), University of Minnesota

NASA Astrophysics Data System (ADS)

Myrbo, A.

2015-12-01

Climatic and environmental change are a powerful hook to engage students and the public with geoscience. Recent lake sediments often feature visual and compositional evidence of anthropogenic changes, which can pique curiosity and serve as a gateway for interest in more remote past changes. Cores provide an integrative, place-based geoscience education/outreach platform: lake dynamics incorporate principles of chemistry, physics, and biology; lake basin formation and sedimentary signals trace back to numerous geoscience subdisciplines. Lakes reflect local changes, and so are inherently place-based and relevant to both rural and urban populations. The esthetics of lakes in the landscape and sediments under the microscope spark the artistic sensibilities of those who do not consider themselves scientists: lakes are readymade for STEAM education. LacCore has exploited the magic of lake sediment cores in its 15 years as an NSF Facility, and now expands to additional environments as the NSF Continental Scientific Drilling Coordination Office. Part of scaling up is the formalization of major support for the Broader Impacts (BI) activities of Facility users. LacCore/CSDCO now musters its collaborative experiences in site REUs and other undergrad research projects, in-depth training of students, teachers, and faculty, a long list of informal education experiences, and common-good software development, to provide assistance to researchers seeking meaningful broader impacts and educators seeking extra- or co-curricular field and laboratory research experiences for their students. Outreach, diversity, and education support includes dissemination of best practices, as well as coordination, administration, and basic capacity for such activities in collaboration with project PIs and students, through no-cost support, or collaborative proposals or supplements from NSF where necessary for project scale. Community-driven research and broadening participation are central to the vision. In the same way that LacCore/CSDCO nurtures drilling and coring project concepts through to fruition, it can foster the BI activities critical to project success in 21st century geoscience, where the challenges are profound, the answers are depressing, and real impacts may occur on the scale of only a few individuals.

Joint optimization of regional water-power systems

NASA Astrophysics Data System (ADS)

Pereira-Cardenal, Silvio J.; Mo, Birger; Gjelsvik, Anders; Riegels, Niels D.; Arnbjerg-Nielsen, Karsten; Bauer-Gottwein, Peter

2016-06-01

Energy and water resources systems are tightly coupled; energy is needed to deliver water and water is needed to extract or produce energy. Growing pressure on these resources has raised concerns about their long-term management and highlights the need to develop integrated solutions. A method for joint optimization of water and electric power systems was developed in order to identify methodologies to assess the broader interactions between water and energy systems. The proposed method is to include water users and power producers into an economic optimization problem that minimizes the cost of power production and maximizes the benefits of water allocation, subject to constraints from the power and hydrological systems. The method was tested on the Iberian Peninsula using simplified models of the seven major river basins and the power market. The optimization problem was successfully solved using stochastic dual dynamic programming. The results showed that current water allocation to hydropower producers in basins with high irrigation productivity, and to irrigation users in basins with high hydropower productivity was sub-optimal. Optimal allocation was achieved by managing reservoirs in very distinct ways, according to the local inflow, storage capacity, hydropower productivity, and irrigation demand and productivity. This highlights the importance of appropriately representing the water users' spatial distribution and marginal benefits and costs when allocating water resources optimally. The method can handle further spatial disaggregation and can be extended to include other aspects of the water-energy nexus.

NASA's Land, Atmosphere Near real-time Capability for EOS (LANCE): Changing patterns in the use of NRT satellite imagery

NASA Astrophysics Data System (ADS)

Davies, D.; Michael, K.; Schmaltz, J. E.; Harrison, S.; Ding, F.; Durbin, P. B.; Boller, R. A.; Cechini, M. F.; Rinsland, P. L.; Ye, G.; Mauoka, E.

2015-12-01

NASA's Land, Atmosphere Near real-time Capability for EOS (Earth Observing System) (LANCE) provides data and imagery approximately 3 hours from satellite observation, to monitor natural events globally and to meet the needs of the near real-time (NRT) applications community. This article describes LANCE, and how the use of NRT data and imagery has evolved. Since 2010 there has been a four-fold increase in both the volume of data and the number of files downloaded. Over the last year there has been a marked shift in the way in which users are accessing NRT imagery; users are gravitating towards Worldview and the Global Imagery Browse Services (GIBS) and away from MODIS Rapid Response, in part due to the increased exposure through social media. In turn this is leading to a broader range of users viewing NASA NRT imagery. This article also describes new, and planned, product enhancements to LANCE. Over the last year, LANCE has expanded to support NRT products from the Advanced Microwave Scanning Radiometer 2 (AMSR2), and the Multi-angle Imaging SpectroRadiometer (MISR). LANCE elements are also planning to ingest and process NRT data from the Visible Infrared Imager Radiometer Suite (VIIRS), and the advanced Ozone Mapping and Profiler Suite (OMPS) instruments onboard the Suomi National Polar-orbiting Partnership (S-NPP) satellite in the near future.

Alternatives to seclusion and restraint in psychiatry and in long-term care facilities for the elderly: perspectives of service users and family members.

PubMed

Gagnon, Marie-Pierre; Desmartis, Marie; Dipankui, Mylène Tantchou; Gagnon, Johanne; St-Pierre, Michèle

2013-01-01

There is growing interest in involving patients in decisions regarding healthcare technologies. This research project was conducted in collaboration with decision makers and health technology assessment agents in order to involve healthcare service users (and their loved ones) in the assessment of alternatives to seclusion and restraint in short-term psychiatric wards and long-term care facilities for the elderly. This paper explores the viewpoints and suggestions of service users and service users' families about alternatives to restraint and seclusion, as well as conditions under which they could be used among adults in short-term psychiatric care and residents in long-term care facilities. Using a semi-structured guide, we held eight focus groups: five with mental health service users and three with family members of elderly people in long-term care facilities. Focus group discussions were digitally recorded and transcribed verbatim, and we performed content analysis using NVivo 8 software. In both care environments, participants emphasized the importance of communicating with service users, as well as assessing their needs and their particular situation, for reducing the use of restraint and seclusion. A better welcome and accompaniment of people admitted for short-term psychiatric care emerged also as key approaches to reduce the use of restraint and seclusion. Long-term care facilities could also reduce the need for restraint and seclusion by creating a stimulating home environment and individualized occupational therapy programs. Participants in both groups suggested that caregivers other than healthcare staff could be more involved, especially peer-support workers in the case of psychiatric care and volunteers in the case of long-term care facilities. Participants suggested that changes were needed at a broader and more systemic level than simply replacing current measures of restraint and seclusion with alternative techniques. They favored an approach focused more on the person than on the techniques: they suggested that listening to and communicating with the service user could reduce the use of restraint and seclusion in both healthcare environments.

Estimating vapor pressures of pure liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haraburda, S.S.

1996-03-01

Calculating the vapor pressures for pure liquid chemicals is a key step in designing equipment for separation of liquid mixtures. Here is a useful way to develop an equation for predicting vapor pressures over a range of temperatures. The technique uses known vapor pressure points for different temperatures. Although a vapor-pressure equation is being showcased in this article, the basic method has much broader applicability -- in fact, users can apply it to develop equations for any temperature-dependent model. The method can be easily adapted for use in software programs for mathematics evaluation, minimizing the need for any programming. Themore » model used is the Antoine equation, which typically provides a good correlation with experimental or measured data.« less

Time code dissemination experiment via the SIRIO-1 VHF transponder

NASA Technical Reports Server (NTRS)

Detoma, E.; Gobbo, G.; Leschiutta, S.; Pettiti, V.

1982-01-01

An experiment to evaluate the possibility of disseminating a time code via the SIRIO-1 satellite, by using the onboard VHF repeater is described. The precision in the synchronization of remote clocks was expected to be of the order of 0.1 to 1 ms. The RF carrier was in the VHF band, so that low cost receivers could be used and then a broader class of users could be served. An already existing repeater, even if not designed specifically for communications could be utilized; the operation of this repeater was not intended to affect any other function of the spacecraft (both the SHF repeater and the VHF telemetry link were active during the time code dissemination via the VHF transponder).

Designing and developing suppository formulations for anti-HIV drug delivery.

PubMed

Ham, Anthony S; Buckheit, Robert W

2017-08-01

Despite a long history of use for rectal and vaginal drug delivery, the current worldwide market for suppositories is limited primarily due to a lack of user acceptability. Therefore, virtually no rational pharmaceutical development of antiviral suppositories has been performed. However, suppositories offer several advantages over other antiviral dosage forms. Current suppository designs have integrated active pharmaceutical ingredients into existing formulation designs without optimization. As such, emerging suppository development has been focused on improving upon the existing classical design to enhance drug delivery and is poised to open suppository drug delivery to a broader range of drugs, including antiretroviral products. Thus, with continuing research into rational suppository design and development, there is significant potential for antiretroviral suppository drug delivery.

An Inter-Personal Information Sharing Model Based on Personalized Recommendations

NASA Astrophysics Data System (ADS)

Kamei, Koji; Funakoshi, Kaname; Akahani, Jun-Ichi; Satoh, Tetsuji

In this paper, we propose an inter-personal information sharing model among individuals based on personalized recommendations. In the proposed model, we define an information resource as shared between people when both of them consider it important --- not merely when they both possess it. In other words, the model defines the importance of information resources based on personalized recommendations from identifiable acquaintances. The proposed method is based on a collaborative filtering system that focuses on evaluations from identifiable acquaintances. It utilizes both user evaluations for documents and their contents. In other words, each user profile is represented as a matrix of credibility to the other users' evaluations on each domain of interests. We extended the content-based collaborative filtering method to distinguish other users to whom the documents should be recommended. We also applied a concept-based vector space model to represent the domain of interests instead of the previous method which represented them by a term-based vector space model. We introduce a personalized concept-base compiled from each user's information repository to improve the information retrieval in the user's environment. Furthermore, the concept-spaces change from user to user since they reflect the personalities of the users. Because of different concept-spaces, the similarity between a document and a user's interest varies for each user. As a result, a user receives recommendations from other users who have different view points, achieving inter-personal information sharing based on personalized recommendations. This paper also describes an experimental simulation of our information sharing model. In our laboratory, five participants accumulated a personal repository of e-mails and web pages from which they built their own concept-base. Then we estimated the user profiles according to personalized concept-bases and sets of documents which others evaluated. We simulated inter-personal recommendation based on the user profiles and evaluated the performance of the recommendation method by comparing the recommended documents to the result of the content-based collaborative filtering.

Evidence-Based Medicine in the Education of Psychiatrists

ERIC Educational Resources Information Center

Srihari, Vinod

2008-01-01

Objective: Evidence-based medicine has an important place in the teaching and practice of psychiatry. Attempts to teach evidence-based medicine skills can be weakened by conceptual confusions feeding a false polarization between traditional clinical skills and evidence-based medicine. Methods: The author develops a broader conception of clinical…

Prognocean Plus: the Science-Oriented Sea Level Prediction System as a Tool for Public Stakeholders

NASA Astrophysics Data System (ADS)

Świerczyńska, M. G.; Miziński, B.; Niedzielski, T.

2015-12-01

The novel real-time system for sea level prediction, known as Prognocean Plus, has been developed as a new generation service available through the Polish supercomputing grid infrastructure. The researchers can access the service at https://prognocean.plgrid.pl/. Although the system is science-oriented, we wish to discuss herein its potentials to enhance ocean management studies carried out routinely by public stakeholders. The system produces the short- and medium-term predictions of global altimetric gridded Sea Level Anomaly (SLA) time series, updated daily. The spatial resolution of the SLA forecasts is 1/4° x 1/4°, while the temporal resolution of prognoses is equal to 1 day. The system computes the predictions of time-variable ocean topography using five data-based models, which are not computationally demanding, enabling us to compare their skillfulness in respect to physically-based approaches commonly used by different sea level prediction systems. However, the aim of the system is not only to compute the predictions for science purposes, but primarily to build a user-oriented platform that serves the prognoses and their statistics to a broader community. Thus, we deliver the SLA forecasts as a rapid service available online. In order to provide potential users with the access to science results the Web Map Service (WMS) for Prognocean Plus is designed. We regularly publish the forecasts, both in the interactive graphical WMS service, available from the browser, as well as through the Web Coverage Service (WCS) standard. The Prognocean Plus system, as an early-response system, may be interesting for public stakeholders. It may be used for marine navigation as well as for climate risk management (delineate areas vulnerable to local sea level rise), marine management (advise offered for offshore activities) and coastal management (early warnings against coastal floodings).

Invasive brain-machine interfaces: a survey of paralyzed patients' attitudes, knowledge and methods of information retrieval.

PubMed

Lahr, Jacob; Schwartz, Christina; Heimbach, Bernhard; Aertsen, Ad; Rickert, Jörn; Ball, Tonio

2015-08-01

Brain-machine interfaces (BMI) are an emerging therapeutic option that can allow paralyzed patients to gain control over assistive technology devices (ATDs). BMI approaches can be broadly classified into invasive (based on intracranially implanted electrodes) and noninvasive (based on skin electrodes or extracorporeal sensors). Invasive BMIs have a favorable signal-to-noise ratio, and thus allow for the extraction of more information than noninvasive BMIs, but they are also associated with the risks related to neurosurgical device implantation. Current noninvasive BMI approaches are typically concerned, among other issues, with long setup times and/or intensive training. Recent studies have investigated the attitudes of paralyzed patients eligible for BMIs, particularly patients affected by amyotrophic lateral sclerosis (ALS). These studies indicate that paralyzed patients are indeed interested in BMIs. Little is known, however, about the degree of knowledge among paralyzed patients concerning BMI approaches or about how patients retrieve information on ATDs. Furthermore, it is not yet clear if paralyzed patients would accept intracranial implantation of BMI electrodes with the premise of decoding improvements, and what the attitudes of a broader range of patients with diseases such as stroke or spinal cord injury are towards this new kind of treatment. Using a questionnaire, we surveyed 131 paralyzed patients for their opinions on invasive BMIs and their attitude toward invasive BMI treatment options. The majority of the patients knew about and had a positive attitude toward invasive BMI approaches. The group of ALS patients was especially open to the concept of BMIs. The acceptance of invasive BMI technology depended on the improvements expected from the technology. Furthermore, the survey revealed that for paralyzed patients, the Internet is an important source of information on ATDs. Websites tailored to prospective BMI users should be further developed to provide reliable information to patients, and also to help to link prospective BMI users with researchers involved in the development of BMI technology.

Invasive brain-machine interfaces: a survey of paralyzed patients’ attitudes, knowledge and methods of information retrieval

NASA Astrophysics Data System (ADS)

Lahr, Jacob; Schwartz, Christina; Heimbach, Bernhard; Aertsen, Ad; Rickert, Jörn; Ball, Tonio

2015-08-01

Objective. Brain-machine interfaces (BMI) are an emerging therapeutic option that can allow paralyzed patients to gain control over assistive technology devices (ATDs). BMI approaches can be broadly classified into invasive (based on intracranially implanted electrodes) and noninvasive (based on skin electrodes or extracorporeal sensors). Invasive BMIs have a favorable signal-to-noise ratio, and thus allow for the extraction of more information than noninvasive BMIs, but they are also associated with the risks related to neurosurgical device implantation. Current noninvasive BMI approaches are typically concerned, among other issues, with long setup times and/or intensive training. Recent studies have investigated the attitudes of paralyzed patients eligible for BMIs, particularly patients affected by amyotrophic lateral sclerosis (ALS). These studies indicate that paralyzed patients are indeed interested in BMIs. Little is known, however, about the degree of knowledge among paralyzed patients concerning BMI approaches or about how patients retrieve information on ATDs. Furthermore, it is not yet clear if paralyzed patients would accept intracranial implantation of BMI electrodes with the premise of decoding improvements, and what the attitudes of a broader range of patients with diseases such as stroke or spinal cord injury are towards this new kind of treatment. Approach. Using a questionnaire, we surveyed 131 paralyzed patients for their opinions on invasive BMIs and their attitude toward invasive BMI treatment options. Main results. The majority of the patients knew about and had a positive attitude toward invasive BMI approaches. The group of ALS patients was especially open to the concept of BMIs. The acceptance of invasive BMI technology depended on the improvements expected from the technology. Furthermore, the survey revealed that for paralyzed patients, the Internet is an important source of information on ATDs. Significance. Websites tailored to prospective BMI users should be further developed to provide reliable information to patients, and also to help to link prospective BMI users with researchers involved in the development of BMI technology.

SMPBS: Web server for computing biomolecular electrostatics using finite element solvers of size modified Poisson-Boltzmann equation.

PubMed

Xie, Yang; Ying, Jinyong; Xie, Dexuan

2017-03-30

SMPBS (Size Modified Poisson-Boltzmann Solvers) is a web server for computing biomolecular electrostatics using finite element solvers of the size modified Poisson-Boltzmann equation (SMPBE). SMPBE not only reflects ionic size effects but also includes the classic Poisson-Boltzmann equation (PBE) as a special case. Thus, its web server is expected to have a broader range of applications than a PBE web server. SMPBS is designed with a dynamic, mobile-friendly user interface, and features easily accessible help text, asynchronous data submission, and an interactive, hardware-accelerated molecular visualization viewer based on the 3Dmol.js library. In particular, the viewer allows computed electrostatics to be directly mapped onto an irregular triangular mesh of a molecular surface. Due to this functionality and the fast SMPBE finite element solvers, the web server is very efficient in the calculation and visualization of electrostatics. In addition, SMPBE is reconstructed using a new objective electrostatic free energy, clearly showing that the electrostatics and ionic concentrations predicted by SMPBE are optimal in the sense of minimizing the objective electrostatic free energy. SMPBS is available at the URL: smpbs.math.uwm.edu © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Knowledge engineering for PACES, the particle accelerator control expert system

NASA Astrophysics Data System (ADS)

Lind, P. C.; Poehlman, W. F. S.; Stark, J. W.; Cousins, T.

1992-04-01

The KN-3000 used at Defense Research Establishment Ottawa is a Van de Graaff particle accelerator employed primarily to produce monoenergetic neutrons for calibrating radiation detectors. To provide training and assistance for new operators, it was decided to develop an expert system for accelerator operation. Knowledge engineering aspects of the expert system are reviewed. Two important issues are involved: the need to encapsulate expert knowledge into the system in a form that facilitates automatic accelerator operation and to partition the system so that time-consuming inferencing is minimized in favor of faster, more algorithmic control. It is seen that accelerator control will require fast, narrowminded decision making for rapid fine tuning, but slower and broader reasoning for machine startup, shutdown, fault diagnosis, and correction. It is also important to render the knowledge base in a form conducive to operator training. A promising form of the expert system involves a hybrid system in which high level reasoning is performed on the host machine that interacts with the user, while an embedded controller employs neural networks for fast but limited adjustment of accelerator performance. This partitioning of duty facilitates a hierarchical chain of command yielding an effective mixture of speed and reasoning ability.

Chemical Transformation System: Cloud Based ...

EPA Pesticide Factsheets

Integrated Environmental Modeling (IEM) systems that account for the fate/transport of organics frequently require physicochemical properties as well as transformation products. A myriad of chemical property databases exist but these can be difficult to access and often do not contain the proprietary chemicals that environmental regulators must consider. We are building the Chemical Transformation System (CTS) to facilitate model parameterization and analysis. CTS integrates a number of physicochemical property calculators into the system including EPI Suite, SPARC, TEST and ChemAxon. The calculators are heterogeneous in their scientific methodologies, technology implementations and deployment stacks. CTS also includes a chemical transformation processing engine that has been loaded with reaction libraries for human biotransformation, abiotic reduction and abiotic hydrolysis. CTS implements a common interface for the disparate calculators accepting molecular identifiers (SMILES, IUPAC, CAS#, user-drawn molecule) before submission for processing. To make the system as accessible as possible and provide a consistent programmatic interface, we wrapped the calculators in a standardized RESTful Application Programming Interface (API) which makes it capable of servicing a much broader spectrum of clients without constraints to interoperability such as operating system or programming language. CTS is hosted in a shared cloud environment, the Quantitative Environmental

Interactive web visualization tools to the results interpretation of a seismic risk study aimed at the emergency levels definition

NASA Astrophysics Data System (ADS)

Rivas-Medina, A.; Gutierrez, V.; Gaspar-Escribano, J. M.; Benito, B.

2009-04-01

Results of a seismic risk assessment study are often applied and interpreted by users unspecialised on the topic or lacking a scientific background. In this context, the availability of tools that help translating essentially scientific contents to broader audiences (such as decision makers or civil defence officials) as well as representing and managing results in a user-friendly fashion, are on indubitable value. On of such tools is the visualization tool VISOR-RISNA, a web tool developed within the RISNA project (financed by the Emergency Agency of Navarre, Spain) for regional seismic risk assessment of Navarre and the subsequent development of emergency plans. The RISNA study included seismic hazard evaluation, geotechnical characterization of soils, incorporation of site effects to expected ground motions, vulnerability distribution assessment and estimation of expected damage distributions for a 10% probability of exceedance in 50 years. The main goal of RISNA was the identification of higher risk area where focusing detailed, local-scale risk studies in the future and the corresponding urban emergency plans. A geographic information system was used to combine different information layers, generate tables of results and represent maps with partial and final results. The visualization tool VISOR-RISNA is intended to facilitate the interpretation and representation of the collection of results, with the ultimate purpose of defining actuation plans. A number of criteria for defining actuation priorities are proposed in this work. They are based on combinations of risk parameters resulting from the risk study (such as expected ground motion and damage and exposed population), as determined by risk assessment specialists. Although the values that these parameters take are a result of the risk study, their distribution in several classes depends on the intervals defined by decision takers or civil defense officials. These criteria provide a ranking of municipalities according to the expected actuation level and eventually, to alert levels. In this regard, the visualization tool constitutes an intuitive and useful tool that the end-user of the risk study may use to optimize and guide its application on emergency planning. The use of this type of tools can be adapted to other scenarios with different boundary conditions (seismicity level, vulnerability distribution) and user profiles (policy makers, stakeholders, students, general public) maintaining the same final goal: to improve the adaptation of the results of a scientific-technical work to the needs of other users with different backgrounds.

Assessing land degradation and acknowledging adaptive policy options to face with changes: an integrated approach applied to a semiarid agropastoral system

NASA Astrophysics Data System (ADS)

Tarrasón, D.; Ravera, F.; Reed, M.; Dougill, A.

2009-04-01

The complexity of assessing land degradation on semiarid systems deals with challenges that have rarely been addressed. Land degradation is a human-induced and permanent reduction of key ecosystem functions and services at different temporal and spatial scale. Initial attempts to assess land degradation at a broader scale were based on expert opinion, however the empirical bases to sustain these estimations are weak and the ecological data are still scarce. In addition, such approaches are essentially subjective and they reflect the objectives and assumptions of those making the assessment, who are rarely land users themselves. Currently, the concept of "land degradation" is debated, and in the last years have emerged a growing number of efforts to develop land degradation participatory assessment methods that could capture a more complex understanding of human-environment interactions. This study proposes an interdisciplinary and hybrid methodology, combining local and scientific knowledge, to assess land degradation in mixed farming systems. Specifically, i) it describes and analyses the mixed farming system and it explores how historically political, social and institutional local factors have interacted with ecological process, ii) it identifies key ecosystem processes and services needed to support the agropastoral systems that are perceived to be under threat from land degradation; iii) it assesses the status and trends of these key ecosystem services; and iv) it identifies and evaluates potential management alternatives to prevent land degradation and cope with changes (e.g. climate change). We show how to achieve, through a co-construction of hybrid knowledge between scientific and farmers, a more accurate and reliable appraisal of land degradation, since farmer's perception is contextualized, dynamic and complex and involves simultaneously multiple temporal and spatial scales and multiple dimensions of analysis that could help the scientific exploration. The study reveals that the ecosystem services' exploration with local actors is a good method to reveal the multiple and sometimes conflictive local strategies and interests at stake. Ecosystem services assessment has also been used as an entry to discuss with local land users about adaptive management strategies to improve soil functions involved in the maintenance of the provision and regulation processes and land productivity that support local livelihoods face to changes. The integrated methodological framework adopted has a positive impact to empower local users, enlarging the access to adequate information and channels of communication between experts/local users, and improving their capacity to use the co-constructed hybrid knowledge. We argue that engaging the relevant and interested actors in the process is key to understand margin of flexibility for dialogue between local users, scientific and policy makers and it is a base for ownership of local actors in decision making processes that facilitates effective soil-land governance. Finally, we discuss how wide institutional changes at different levels are needed to support agro-environmental policies for communities, small and medium farmers and to undertake new adaptive management strategies to cope with uncertainties of future changes.

Exploring Agricultural Livelihood Transitions with an Agent-Based Virtual Laboratory: Global Forces to Local Decision-Making

PubMed Central

Magliocca, Nicholas R.; Brown, Daniel G.; Ellis, Erle C.

2013-01-01

Rural populations are undergoing rapid changes in both their livelihoods and land uses, with associated impacts on ecosystems, global biogeochemistry, and climate change. A primary challenge is, thus, to explain these shifts in terms of the actors and processes operating within a variety of land systems in order to understand how land users might respond locally to future changes in broader-scale environmental and economic conditions. Using ‘induced intensification’ theory as a benchmark, we develop a generalized agent-based model to investigate mechanistic explanations of relationships between agricultural intensity and population density, environmental suitability, and market influence. Land-use and livelihood decisions modeled from basic micro-economic theories generated spatial and temporal patterns of agricultural intensification consistent with predictions of induced intensification theory. Further, agent actions in response to conditions beyond those described by induced intensification theory were explored, revealing that interactions among environmental constraints, population pressure, and market influence may produce transitions to multiple livelihood regimes of varying market integration. The result is new hypotheses that could modify and enrich understanding of the classic relationship between agricultural intensity and population density. The strength of this agent-based model and the experimental results is the generalized form of the decision-making processes underlying land-use and livelihood transitions, creating the prospect of a virtual laboratory for systematically generating hypotheses of how agent decisions and interactions relate to observed land-use and livelihood patterns across diverse land systems. PMID:24039892

Obstetrics in a Time of Violence: Mexican Midwives Critique Routine Hospital Practices.

PubMed

Zacher Dixon, Lydia

2015-12-01

Mexican midwives have long taken part in a broader Latin American trend to promote "humanized birth" as an alternative to medicalized interventions in hospital obstetrics. As midwives begin to regain authority in reproductive health and work within hospital units, they come to see the issue not as one of mere medicalization but of violence and violation. Based on ethnographic fieldwork with midwives from across Mexico during a time of widespread social violence, my research examines an emergent critique of hospital birth as a site of what is being called violencia obstétrica (obstetric violence). In this critique, women are discussed as victims of explicit abuse by hospital staff and by the broader health care infrastructures. By reframing obstetric practices as violent-as opposed to medicalized-these midwives seek to situate their concerns about women's health care in Mexico within broader regional discussions about violence, gender, and inequality. © 2015 by the American Anthropological Association.

Based on user interest level of modeling scenarios and browse content

NASA Astrophysics Data System (ADS)

Zhao, Yang

2017-08-01

User interest modeling is the core of personalized service, taking into account the impact of situational information on user preferences, the user behavior days of financial information. This paper proposes a method of user interest modeling based on scenario information, which is obtained by calculating the similarity of the situation. The user's current scene of the approximate scenario set; on the "user - interest items - scenarios" three-dimensional model using the situation pre-filtering method of dimension reduction processing. View the content of the user interested in the theme, the analysis of the page content to get each topic of interest keywords, based on the level of vector space model user interest. The experimental results show that the user interest model based on the scenario information is within 9% of the user's interest prediction, which is effective.

The Windows to the Universe Project: Using the Internet to Support K-12 Science Education

NASA Astrophysics Data System (ADS)

Gardiner, L.; Johnson, R.; Bergman, J.; Russell, R.; Genyuk, J.; La Grave, M.

2003-12-01

The World Wide Web can be a powerful tool for reaching the public as well as students and teachers around the world, supporting both formal and informal science education. The Windows to the Universe Project, initiated in 1995, provides a case study of approaches for the use of the web to support earth and space science education and literacy efforts. Through the use of innovative approaches such as easy to use design, multi-level content, and science concepts presented in a broader background context that includes connections to culture and the humanities, Windows to the Universe is an accessible format for individuals of various ages and learning styles. A large global audience regularly uses the web site to learn about earth and space science as well as related humanities content such as myths from around the world. User surveys show that the site has over 4 millions users per year, 65 percent of which are K-12 teachers and students. Approximately 46 percent of users access the site once per week or more. Recently, we have had the opportunity to expand our efforts while we continue to update existing content based on new scientific findings and events. Earth science content on Windows to the Universe is currently growing with a new geology section and development efforts are underway to expand our space weather content with a new curriculum. Educational games allow users to learn about space in a playful context, and an online journaling tool further integrates literacy into the learning experience. In addition, we are currently translating the entire Windows to the Universe web site into Spanish. We have included educators in the project as co-designers from its inception, and by aggressively utilizing and providing professional development opportunities for teachers, the web site is now used in thousands of classrooms around the world. In the past year we have continued to support K-12 educators by adding to our suite of classroom activities and leading professional development workshops and short courses. Core funding for the project is provided from the NASA Office of Space Science Information Technology Research Program, the NASA Earth Science Enterprise Education Program, and the National Science Foundation.

Precipitation links (PrecipLinks) - a prototype directory for precipitation information

NASA Technical Reports Server (NTRS)

Velanthapillia, Balendran; Stocker, Erich Franz

2006-01-01

This poster describes a web directory of research oriented precipitation links. In this era of sophisticated search engines and web agents, it might seem counterproductive to establish such a directory of links. However, entering precipitation into a search engine like google will yield over one million hits. To further exacerbate this situation many of the returned links are dead, duplicates of other links, incomplete, or only marginally related to research precipitation or even the broader precipitation area. Sometimes connecting the linked URL causes the browser to lose context and not be able to get back to the original page. Even using more sophisticated search engines query parameters or agents while reducing the overall return doesn't eliminate all of the other issues listed. As part of the development of the measurement-based Precipitation Processing System (PPS) that will support Tropical Rainfall Measuring Mission (TRMM) version 7 reprocessing and the Global Precipitation Measurement (GPM) mission a precipitation links (PrecipLinks) facility is being developed. PrecipLinks is intended to share locations of other sites that contain information or data pertaining to precipitation research. Potential contributors can log-on to the PrecipLinks website and register their site for inclusion in the directory. The price for inclusion is the requirement to place a link back to PrecipLinks on the webpage that is registered. This ensures that users will be able to easily get back to PrecipLinks regardless of any context issues that browsers might have. Perhaps more importantly users while visiting one site that they know can be referred to a location that has many others sites with which they might not be familiar. PrecipLinks is designed to have a very flat structure. This poster summarizes these categories (information, data, services) and the reasons for their selection. Providers may register multiple pages to which they wish to direct users. However, each page may be attached to only one of these categories. Each page to which they refer users will also have a return link to PrecipLinks. The poster describes the operation of the system both the automated and the human processes. It also provides images for the various steps in the registration and use.

JAMSTEC E-library of Deep-sea Images (J-EDI) Realizes a Virtual Journey to the Earth's Unexplored Deep Ocean

NASA Astrophysics Data System (ADS)

Sasaki, T.; Azuma, S.; Matsuda, S.; Nagayama, A.; Ogido, M.; Saito, H.; Hanafusa, Y.

2016-12-01

The Japan Agency for Marine-Earth Science and Technology (JAMSTEC) archives a large amount of deep-sea research videos and photos obtained by JAMSTEC's research submersibles and vehicles with cameras. The web site "JAMSTEC E-library of Deep-sea Images : J-EDI" (http://www.godac.jamstec.go.jp/jedi/e/) has made videos and photos available to the public via the Internet since 2011. Users can search for target videos and photos by keywords, easy-to-understand icons, and dive information at J-EDI because operating staffs classify videos and photos as to contents, e.g. living organism and geological environment, and add comments to them.Dive survey data including videos and photos are not only valiant academically but also helpful for education and outreach activities. With the aim of the improvement of visibility for broader communities, we added new functions of 3-dimensional display synchronized various dive survey data with videos in this year.New Functions Users can search for dive survey data by 3D maps with plotted dive points using the WebGL virtual map engine "Cesium". By selecting a dive point, users can watch deep-sea videos and photos and associated environmental data, e.g. water temperature, salinity, rock and biological sample photos, obtained by the dive survey. Users can browse a dive track visualized in 3D virtual spaces using the WebGL JavaScript library. By synchronizing this virtual dive track with videos, users can watch deep-sea videos recorded at a point on a dive track. Users can play an animation which a submersible-shaped polygon automatically traces a 3D virtual dive track and displays of dive survey data are synchronized with tracing a dive track. Users can directly refer to additional information of other JAMSTEC data sites such as marine biodiversity database, marine biological sample database, rock sample database, and cruise and dive information database, on each page which a 3D virtual dive track is displayed. A 3D visualization of a dive track makes users experience a virtual dive survey. In addition, by synchronizing a virtual dive track with videos, it is easy to understand living organisms and geological environments of a dive point. Therefore, these functions will visually support understanding of deep-sea environments in lectures and educational activities.

Exemplar-Based Image and Video Stylization Using Fully Convolutional Semantic Features.

PubMed

Zhu, Feida; Yan, Zhicheng; Bu, Jiajun; Yu, Yizhou

2017-05-10

Color and tone stylization in images and videos strives to enhance unique themes with artistic color and tone adjustments. It has a broad range of applications from professional image postprocessing to photo sharing over social networks. Mainstream photo enhancement softwares, such as Adobe Lightroom and Instagram, provide users with predefined styles, which are often hand-crafted through a trial-and-error process. Such photo adjustment tools lack a semantic understanding of image contents and the resulting global color transform limits the range of artistic styles it can represent. On the other hand, stylistic enhancement needs to apply distinct adjustments to various semantic regions. Such an ability enables a broader range of visual styles. In this paper, we first propose a novel deep learning architecture for exemplar-based image stylization, which learns local enhancement styles from image pairs. Our deep learning architecture consists of fully convolutional networks (FCNs) for automatic semantics-aware feature extraction and fully connected neural layers for adjustment prediction. Image stylization can be efficiently accomplished with a single forward pass through our deep network. To extend our deep network from image stylization to video stylization, we exploit temporal superpixels (TSPs) to facilitate the transfer of artistic styles from image exemplars to videos. Experiments on a number of datasets for image stylization as well as a diverse set of video clips demonstrate the effectiveness of our deep learning architecture.

Job optimization in ATLAS TAG-based distributed analysis

NASA Astrophysics Data System (ADS)

Mambelli, M.; Cranshaw, J.; Gardner, R.; Maeno, T.; Malon, D.; Novak, M.

2010-04-01

The ATLAS experiment is projected to collect over one billion events/year during the first few years of operation. The efficient selection of events for various physics analyses across all appropriate samples presents a significant technical challenge. ATLAS computing infrastructure leverages the Grid to tackle the analysis across large samples by organizing data into a hierarchical structure and exploiting distributed computing to churn through the computations. This includes events at different stages of processing: RAW, ESD (Event Summary Data), AOD (Analysis Object Data), DPD (Derived Physics Data). Event Level Metadata Tags (TAGs) contain information about each event stored using multiple technologies accessible by POOL and various web services. This allows users to apply selection cuts on quantities of interest across the entire sample to compile a subset of events that are appropriate for their analysis. This paper describes new methods for organizing jobs using the TAGs criteria to analyze ATLAS data. It further compares different access patterns to the event data and explores ways to partition the workload for event selection and analysis. Here analysis is defined as a broader set of event processing tasks including event selection and reduction operations ("skimming", "slimming" and "thinning") as well as DPD making. Specifically it compares analysis with direct access to the events (AOD and ESD data) to access mediated by different TAG-based event selections. We then compare different ways of splitting the processing to maximize performance.

Driving color management into the office

NASA Astrophysics Data System (ADS)

Newman, Todd

2007-01-01

In much the same way that the automobile industry develops new technologies in racing cars and then brings them to a broader market for commercial and consumer vehicles, CIE Division 8 is trying to spread color management from the graphic arts market into the broader office and home markets. In both areas, the professional environment is characterized by highly motivated, highly trained practitioners who see their activity as an end in itself and have access to expensive technology, state of the art measurement and calibration equipment, and an environment that, if not as sedate as a research laboratory, is controlled and well-understood. In contrast, the broader market features users who have relatively little training at the imaging tasks and see them as a means to an end, which is where their real attention is focused. These users have mass-market equipment and little or no equipment for measurement and calibration. They use their tools (cars or imaging equipment) in a variety of environments under highly unpredictable conditions. The challenge to the automobile and imaging engineering communities is to design practical solutions to work in these real world environments that are less demanding in terms of strict performance, but more demanding in terms of flexibility and robustness. In the graphic arts, we have standards that tell us how to perform comparisons between printed images (hardcopy) and images displayed on a screen (softcopy). The users are told to use sequential binocular comparisons using memory matching, where they first adapt completely to one viewing condition, study one image, and then adapt to the other viewing condition and compare the second image against their memory of the first. This provides a nicely controlled environment where the observer's state of adaptation is easy to calculate. Unfortunately, in the office and home markets, users insist on comparing the softcopy and hardcopy side by side, and rapidly switching their gaze between the two images. In such a situation, it is much harder to say what the observer's adaptation is. There are two phenomena involved. First is mixed chromatic adaptation, where the white point to which the observer is adapted is a mixture of the white points of the display and the hardcopy. Related to this is what is known as incomplete chromatic adaptation, where the media white point does not appear perfectly white to the observer. The report from TC8-04 provides equations that extend CIECAM02 to account for mixed and incomplete chromatic adaptation. Those who work in the graphic arts know that if you want to make critical color judgments, you need a controlled lighting environment. Most color management systems are designed around a white point of D50, even for displays. This white point is the default setting for most spectrophotometers, for example. In the office environment, the situation is much less clear. There are many different lamps used in office lighting with many different white points. There have been no broad, multi-national studies of office lighting conditions, so we cannot say what typical office lighting is like, or even if there are any conditions that could be called "typical." TC8-10 is designing such a study. We intend to look at the spectral power distributions and illumination levels found in areas of offices where people tend to look at images. Once we have gathered this data, we will analyze it to see if any trends can be found. There may be similarities within geographic regions, job categories, or seasonal variations that would be useful to know. CIE Division 8 members hope that by applying the research results from our technical committees, color engineers will be able to help their customers get pleasing results in the uncalibrated, unmeasured, unpredictable environment that is the office workplace.

OpenTrials: towards a collaborative open database of all available information on all clinical trials.

PubMed

Goldacre, Ben; Gray, Jonathan

2016-04-08

OpenTrials is a collaborative and open database for all available structured data and documents on all clinical trials, threaded together by individual trial. With a versatile and expandable data schema, it is initially designed to host and match the following documents and data for each trial: registry entries; links, abstracts, or texts of academic journal papers; portions of regulatory documents describing individual trials; structured data on methods and results extracted by systematic reviewers or other researchers; clinical study reports; and additional documents such as blank consent forms, blank case report forms, and protocols. The intention is to create an open, freely re-usable index of all such information and to increase discoverability, facilitate research, identify inconsistent data, enable audits on the availability and completeness of this information, support advocacy for better data and drive up standards around open data in evidence-based medicine. The project has phase I funding. This will allow us to create a practical data schema and populate the database initially through web-scraping, basic record linkage techniques, crowd-sourced curation around selected drug areas, and import of existing sources of structured and documents. It will also allow us to create user-friendly web interfaces onto the data and conduct user engagement workshops to optimise the database and interface designs. Where other projects have set out to manually and perfectly curate a narrow range of information on a smaller number of trials, we aim to use a broader range of techniques and attempt to match a very large quantity of information on all trials. We are currently seeking feedback and additional sources of structured data.

The Internet As a Large-Scale Complex System

NASA Astrophysics Data System (ADS)

Park, Kihong; Willinger, Walter

2005-06-01

The Internet may be viewed as a "complex system" with diverse features and many components that can give rise to unexpected emergent phenomena, revealing much about its own engineering. This book brings together chapter contributions from a workshop held at the Santa Fe Institute in March 2001. This volume captures a snapshot of some features of the Internet that may be fruitfully approached using a complex systems perspective, meaning using interdisciplinary tools and methods to tackle the subject area. The Internet penetrates the socioeconomic fabric of everyday life; a broader and deeper grasp of the Internet may be needed to meet the challenges facing the future. The resulting empirical data have already proven to be invaluable for gaining novel insights into the network's spatio-temporal dynamics, and can be expected to become even more important when tryin to explain the Internet's complex and emergent behavior in terms of elementary networking-based mechanisms. The discoveries of fractal or self-similar network traffic traces, power-law behavior in network topology and World Wide Web connectivity are instances of unsuspected, emergent system traits. Another important factor at the heart of fair, efficient, and stable sharing of network resources is user behavior. Network systems, when habited by selfish or greedy users, take on the traits of a noncooperative multi-party game, and their stability and efficiency are integral to understanding the overall system and its dynamics. Lastly, fault-tolerance and robustness of large-scale network systems can exhibit spatial and temporal correlations whose effective analysis and management may benefit from rescaling techniques applied in certain physical and biological systems. The present book will bring together several of the leading workers involved in the analysis of complex systems with the future development of the Internet.

"The Florence Experience": A multimedia and multisensory guidebook for cultural towns inspired by Universal Design approach.

PubMed

Lauría, Antonio

2016-02-15

In order to plan a trip, tourists with disabilities need to gather and analyse a broad range of information concerning the features of the places and services with which they are going to interact. For these people, guidebooks may represent an important source of information for gaining prior knowledge about the various critical situations they may experience as tourists. Generally, disabled people find tourist information on dedicated communication tools; guidebooks for the disabled often provide information for wheelchair users only. The aim of the research project was to develop a mainstream guidebook with supplementary tourist information both for people with impaired vision and for people with reduced mobility. The communication project behind "The Florence Experience" guidebook is inspired by both the Universal Design approach and the Performance Design approach. This article describes a case study and provides suggestions for planning in similar situations. It is also part of a broader research project relating to the communication about urban spaces accessibility. The main outcome of the research project is a multimedia and multisensory bilingual guidebook (in Italian and English) that provides information in four separate coordinated forms: a paper-based guidebook, web pages, MP3 audio files, and portable tactile maps. Creating a guidebook for all is a tough challenge that requires a highly articulated vision and the cooperation of different fields of knowledge and skills. Despite the limits described in the paper, "The Florence Experience" guidebook is, in our opinion, a considerable step forward with respect to the majority of available guidebooks both because it is a unique information tool for disabled and non-disabled people and because, unlike the majority of the guidebooks for disabled people, it does not only consider the needs of wheelchair users.

Building the Community Online Resource for Statistical Seismicity Analysis (CORSSA)

NASA Astrophysics Data System (ADS)

Michael, A. J.; Wiemer, S.; Zechar, J. D.; Hardebeck, J. L.; Naylor, M.; Zhuang, J.; Steacy, S.; Corssa Executive Committee

2010-12-01

Statistical seismology is critical to the understanding of seismicity, the testing of proposed earthquake prediction and forecasting methods, and the assessment of seismic hazard. Unfortunately, despite its importance to seismology - especially to those aspects with great impact on public policy - statistical seismology is mostly ignored in the education of seismologists, and there is no central repository for the existing open-source software tools. To remedy these deficiencies, and with the broader goal to enhance the quality of statistical seismology research, we have begun building the Community Online Resource for Statistical Seismicity Analysis (CORSSA). CORSSA is a web-based educational platform that is authoritative, up-to-date, prominent, and user-friendly. We anticipate that the users of CORSSA will range from beginning graduate students to experienced researchers. More than 20 scientists from around the world met for a week in Zurich in May 2010 to kick-start the creation of CORSSA: the format and initial table of contents were defined; a governing structure was organized; and workshop participants began drafting articles. CORSSA materials are organized with respect to six themes, each containing between four and eight articles. The CORSSA web page, www.corssa.org, officially unveiled on September 6, 2010, debuts with an initial set of approximately 10 to 15 articles available online for viewing and commenting with additional articles to be added over the coming months. Each article will be peer-reviewed and will present a balanced discussion, including illustrative examples and code snippets. Topics in the initial set of articles will include: introductions to both CORSSA and statistical seismology, basic statistical tests and their role in seismology; understanding seismicity catalogs and their problems; basic techniques for modeling seismicity; and methods for testing earthquake predictability hypotheses. A special article will compare and review available statistical seismology software packages.

Beliefs, decision-making, and dialogue about complementary and alternative medicine (CAM) within families using CAM: a qualitative study.

PubMed

Nichol, James; Thompson, Elizabeth A; Shaw, Alison

2011-02-01

The rise in complementary and alternative medicine (CAM) use is well documented. Surveys provide varying estimates of the prevalence of CAM use. Qualitative research has explored individuals' decision-making regarding CAM. This study aimed to examine the family as a context for beliefs, decision-making, and dialogue about CAM. Families were recruited via the Avon Longitudinal Study of Parents and Children. A subsample of CAM users was targeted using purposeful sampling. Focus groups and interviews were conducted with 15 families and the data were analyzed thematically. Family understandings and beliefs about CAM: CAM was understood as treatments provided outside mainstream care, offering a more "natural" and "holistic" approach, tailored to individual needs and overlapping with wider healthy lifestyle practices. Hierarchies of acceptability of CAM: Physical and "mainstream" therapies were widely supported, with "fringe" therapies producing the most polarized views. There was a belief particularly among fathers and young people that certain therapies rely on "placebo" effects and their value was contested. Types of CAM users within families: Family members were predominantly "pragmatic" CAM users, with "committed" users (all mothers) characterized by deeper philosophical commitment to CAM and skepticism toward conventional medicine. Family dynamics of CAM decision-making: Mothers tended to "champion" CAM within families, while not determining family CAM use. Fathers largely positioned themselves as lacking expertise or skeptical of CAM. Young people were beginning to articulate independent and more critical views of CAM, some directly challenging their mother's perspective. However, all families shared openness to CAM as part of broader beliefs in proactive healthy lifestyles. Family focus groups and interviews allow a window on beliefs, decision-making, and dialogue about CAM within families, illuminating the CAM "champion" role held by mothers, and young people's developing autonomy regarding health beliefs and decision-making.

Effects of transit bus interior configuration on performance of wheeled mobility users during simulated boarding and disembarking.

PubMed

D'Souza, Clive; Paquet, Victor; Lenker, James A; Steinfeld, Edward

2017-07-01

The emergence of low-floor bus designs and related regulatory standards in the U.S. have resulted in substantial improvements in public transit accessibility. However, passengers using wheeled mobility devices still experience safety concerns and inefficiencies in boarding, disembarking, and interior circulation on low-floor buses. This study investigates effects of low-floor bus interior configuration and passenger crowding on boarding and disembarking efficiency and safety. Users of manual wheelchairs (n = 18), powered wheelchairs (n = 21) and electric scooters (n = 9) simulated boarding and disembarking in three interior layout configurations at low and high passenger crowding conditions on a full-scale laboratory mock-up of a low-floor bus. Dependent measures comprised task times and critical incidents during access ramp use, fare payment, and movement to and from the doorway and wheeled mobility securement area. Individual times for unassisted boarding ranged from 15.2 to 245.3 s and for disembarking ranged from 9.1 to 164.6 s across layout and passenger crowding conditions. Nonparametric analysis of variance showed significant differences and interactions across vehicle design conditions, passenger load and mobility device type on user performance. The configuration having electronic on-board fare payment, rear-bus entrance doorways and adjacent device securement areas demonstrated greatest efficiency and safety. High passenger load adversely impacted efficiency and frequency of critical incidents during on-board circulation across all three layouts. Findings have broader implications for improving transit system efficiency and quality of service across the spectrum of transit users. Copyright © 2017 Elsevier Ltd. All rights reserved.

Exploiting Aura OMI Level 2 Data with High Resolution Visualization

NASA Astrophysics Data System (ADS)

Wei, J. C.; Yang, W.; Johnson, J. E.; Zhao, P.; Gerasimov, I. V.; Pham, L.; Vicente, G. A.; Shen, S.

2014-12-01

Satellite data products are important for a wide variety of applications that can bring far-reaching benefits to the science community and the broader society. These benefits can best be achieved if the satellite data are well utilized and interpreted, such as model inputs from satellite, or extreme event (such as volcano eruption, dust storm, …etc) interpretation from satellite. Unfortunately, this is not always the case, despite the abundance and relative maturity of numerous satellite data products provided by NASA and other organizations. One way to help users better understand the satellite data is to provide data along with 'Images', including accurate pixel-level (Level 2) information, pixel coverage area delineation, and science team recommended quality screening for individual geophysical parameters. Goddard Earth Sciences Data and Information Services Center (GES DISC) always strives to best support (i.e., Software-as-a-service, SaaS) the user-community for NASA Earth Science Data. In this case, we will present a new visualization tool that helps users exploiting Aura Ozone Monitoring Instrument (OMI) Level 2 data. This new visualization service utilizes Open Geospatial Consortium (OGC) standard-compliant Web Mapping Service (WMS) and Web Coverage Service (WCS) calls in the backend infrastructure. The functionality of the service allows users to select data sources (e.g., multiple parameters under the same measurement, like NO2 and SO2 from OMI Level 2 or same parameter with different methods of aggregation, like NO2 in OMNO2G and OMNO2D products), defining area-of-interest and temporal extents, zooming, panning, overlaying, sliding, and data subsetting and reformatting. The interface will also be able to connect to other OGC WMS and WCS servers, which will greatly enhance its expandability to integrate additional outside data/map sources (such as Global Imagery Browse Services (GIBS)).

Can Broader Diffusion of Value-Based Insurance Design Increase Benefits from US Health Care without Increasing Costs? Evidence from a Computer Simulation Model

PubMed Central

Scott Braithwaite, R.; Omokaro, Cynthia; Justice, Amy C.; Nucifora, Kimberly; Roberts, Mark S.

2010-01-01

Background Evidence suggests that cost sharing (i.e.,copayments and deductibles) decreases health expenditures but also reduces essential care. Value-based insurance design (VBID) has been proposed to encourage essential care while controlling health expenditures. Our objective was to estimate the impact of broader diffusion of VBID on US health care benefits and costs. Methods and Findings We used a published computer simulation of costs and life expectancy gains from US health care to estimate the impact of broader diffusion of VBID. Two scenarios were analyzed: (1) applying VBID solely to pharmacy benefits and (2) applying VBID to both pharmacy benefits and other health care services (e.g., devices). We assumed that cost sharing would be eliminated for high-value services (<$100,000 per life-year), would remain unchanged for intermediate- or unknown-value services ($100,000–$300,000 per life-year or unknown), and would be increased for low-value services (>$300,000 per life-year). All costs are provided in 2003 US dollars. Our simulation estimated that approximately 60% of health expenditures in the US are spent on low-value services, 20% are spent on intermediate-value services, and 20% are spent on high-value services. Correspondingly, the vast majority (80%) of health expenditures would have cost sharing that is impacted by VBID. With prevailing patterns of cost sharing, health care conferred 4.70 life-years at a per-capita annual expenditure of US$5,688. Broader diffusion of VBID to pharmaceuticals increased the benefit conferred by health care by 0.03 to 0.05 additional life-years, without increasing costs and without increasing out-of-pocket payments. Broader diffusion of VBID to other health care services could increase the benefit conferred by health care by 0.24 to 0.44 additional life-years, also without increasing costs and without increasing overall out-of-pocket payments. Among those without health insurance, using cost saving from VBID to subsidize insurance coverage would increase the benefit conferred by health care by 1.21 life-years, a 31% increase. Conclusion Broader diffusion of VBID may amplify benefits from US health care without increasing health expenditures. Please see later in the article for the Editors' Summary PMID:20169114

Identifying online user reputation in terms of user preference

NASA Astrophysics Data System (ADS)

Dai, Lu; Guo, Qiang; Liu, Xiao-Lu; Liu, Jian-Guo; Zhang, Yi-Cheng

2018-03-01

Identifying online user reputation is significant for online social systems. In this paper, taking into account the preference physics of online user collective behaviors, we present an improved group-based rating method for ranking online user reputation based on the user preference (PGR). All the ratings given by each specific user are mapped to the same rating criteria. By grouping users according to their mapped ratings, the online user reputation is calculated based on the corresponding group sizes. Results for MovieLens and Netflix data sets show that the AUC values of the PGR method can reach 0.9842 (0.9493) and 0.9995 (0.9987) for malicious (random) spammers, respectively, outperforming the results generated by the traditional group-based method, which indicates that the online preference plays an important role for measuring user reputation.

The characteristics and experience of community food program users in arctic Canada: a case study from Iqaluit, Nunavut

PubMed Central

2012-01-01

Background Community food programs (CFPs), including soup kitchens and food banks, are a recent development in larger settlements in the Canadian Arctic. Our understanding of utilization of these programs is limited as food systems research has not studied the marginalised and transient populations using CFPs, constraining service planning for some of the most vulnerable community members. This paper reports on a baseline study conducted with users of CFPs in Iqaluit, Nunavut, to identify and characterize utilization and document their food security experience. Methods Open ended interviews and a fixed-choice survey on a census (n = 94) were conducted with of users of the food bank, soup kitchen, and friendship centre over a 1 month period, along with key informant interviews. Results Users of CFPs are more likely to be Inuit, be unemployed, and have not completed high school compared to the general Iqaluit population, while also reporting high dependence on social assistance, low household income, and an absence of hunters in the household. The majority report using CFPs for over a year and on a regular basis. Conclusions The inability of users to obtain sufficient food must be understood in the context of socio-economic transformations that have affected Inuit society over the last half century as former semi-nomadic hunting groups were resettled into permanent settlements. The resulting livelihood changes profoundly affected how food is produced, processed, distributed, and consumed, and the socio-cultural relationships surrounding such activities. Consequences have included the rising importance of material resources for food access, the weakening of social safety mechanisms through which more vulnerable community members would have traditionally been supported, and acculturative stress. Addressing these broader challenges is essential for food policy, yet CFPs also have an essential role in providing for those who would otherwise have limited food access. PMID:22720722

ISCE: A Modular, Reusable Library for Scalable SAR/InSAR Processing

NASA Astrophysics Data System (ADS)

Agram, P. S.; Lavalle, M.; Gurrola, E. M.; Sacco, G. F.; Rosen, P. A.

2016-12-01

Traditional community SAR/InSAR processing software tools have primarily focused on differential interferometry and Solid Earth applications. The InSAR Scientific Computing Environment (ISCE) was specifically designed to support the Earth Sciences user community as well as large scale operational processing tasks, thanks to its two-layered (Python+C/Fortran) architecture and modular framework. ISCE is freely distributed as a source tarball, allowing advanced users to modify and extend it for their research purposes and developing exploratory applications, while providing a relatively simple user interface for novice users to perform routine data analysis efficiently. Modular design of the ISCE library also enables easier development of applications to address the needs of Ecosystems, Cryosphere and Disaster Response communities in addition to the traditional Solid Earth applications. In this talk, we would like to emphasize the broader purview of the ISCE library and some of its unique features that sets it apart from other freely available community software like GMTSAR and DORIS, including: Support for multiple geometry regimes - Native Doppler (ALOS-1) as well Zero Doppler (ESA missions) systems. Support for data acquired by airborne platforms - e.g, JPL's UAVSAR and AirMOSS, DLR's F-SAR. Radiometric Terrain Correction - Auxiliary output layers from the geometry modules include projection angles, incidence angles, shadow-layover masks. Dense pixel offsets - Parallelized amplitude cross correlation for cryosphere / ionospheric correction applications. Rubber sheeting - Pixel-by-pixel offsets fields for resampling slave imagery for geometric co-registration/ ionospheric corrections. Preliminary Tandem-X processing support - Bistatic geometry modules. Extensibility to support other non-Solid Earth missions - Modules can be directly adopted for use with other SAR missions, e.g., SWOT. Preliminary support for multi-dimensional data products- multi-polarization, multi-frequency, multi-temporal, multi-baseline stacks via the PLANT and GIAnT toolboxes. Rapid prototyping - Geometry manipulation functionality at the python level allows users to prototype and test processing modules at the interpreter level before optimal implementation in C/C++/Fortran.

Spatial Knowledge Infrastructures - Creating Value for Policy Makers and Benefits the Community

NASA Astrophysics Data System (ADS)

Arnold, L. M.

2016-12-01

The spatial data infrastructure is arguably one of the most significant advancements in the spatial sector. It's been a game changer for governments, providing for the coordination and sharing of spatial data across organisations and the provision of accessible information to the broader community of users. Today however, end-users such as policy-makers require far more from these spatial data infrastructures. They want more than just data; they want the knowledge that can be extracted from data and they don't want to have to download, manipulate and process data in order to get the knowledge they seek. It's time for the spatial sector to reduce its focus on data in spatial data infrastructures and take a more proactive step in emphasising and delivering the knowledge value. Nowadays, decision-makers want to be able to query at will the data to meet their immediate need for knowledge. This is a new value proposal for the decision-making consumer and will require a shift in thinking. This paper presents a model for a Spatial Knowledge Infrastructure and underpinning methods that will realise a new real-time approach to delivering knowledge. The methods embrace the new capabilities afforded through the sematic web, domain and process ontologies and natural query language processing. Semantic Web technologies today have the potential to transform the spatial industry into more than just a distribution channel for data. The Semantic Web RDF (Resource Description Framework) enables meaning to be drawn from data automatically. While pushing data out to end-users will remain a central role for data producers, the power of the semantic web is that end-users have the ability to marshal a broad range of spatial resources via a query to extract knowledge from available data. This can be done without actually having to configure systems specifically for the end-user. All data producers need do is make data accessible in RDF and the spatial analytics does the rest.

The characteristics and experience of community food program users in arctic Canada: a case study from Iqaluit, Nunavut.

PubMed

Ford, James; Lardeau, Marie-Pierre; Vanderbilt, Will

2012-06-21

Community food programs (CFPs), including soup kitchens and food banks, are a recent development in larger settlements in the Canadian Arctic. Our understanding of utilization of these programs is limited as food systems research has not studied the marginalised and transient populations using CFPs, constraining service planning for some of the most vulnerable community members. This paper reports on a baseline study conducted with users of CFPs in Iqaluit, Nunavut, to identify and characterize utilization and document their food security experience. Open ended interviews and a fixed-choice survey on a census (n = 94) were conducted with of users of the food bank, soup kitchen, and friendship centre over a 1 month period, along with key informant interviews. Users of CFPs are more likely to be Inuit, be unemployed, and have not completed high school compared to the general Iqaluit population, while also reporting high dependence on social assistance, low household income, and an absence of hunters in the household. The majority report using CFPs for over a year and on a regular basis. The inability of users to obtain sufficient food must be understood in the context of socio-economic transformations that have affected Inuit society over the last half century as former semi-nomadic hunting groups were resettled into permanent settlements. The resulting livelihood changes profoundly affected how food is produced, processed, distributed, and consumed, and the socio-cultural relationships surrounding such activities. Consequences have included the rising importance of material resources for food access, the weakening of social safety mechanisms through which more vulnerable community members would have traditionally been supported, and acculturative stress. Addressing these broader challenges is essential for food policy, yet CFPs also have an essential role in providing for those who would otherwise have limited food access.

The Land Use and Land Cover Dichotomy: A Comparison of Two Land Classification Systems in Support of Urban Earth Science Applications

NASA Technical Reports Server (NTRS)

McAllister, William K.

2003-01-01

One is likely to read the terms 'land use' and 'land cover' in the same sentence, yet these concepts have different origins and different applications. Land cover is typically analyzed by earth scientists working with remotely sensed images. Land use is typically studied by urban planners who must prescribe solutions that could prevent future problems. This apparent dichotomy has led to different classification systems for land-based data. The works of earth scientists and urban planning practitioners are beginning to come together in the field of spatial analysis and in their common use of new spatial analysis technology. In this context, the technology can stimulate a common 'language' that allows a broader sharing of ideas. The increasing amount of land use and land cover change challenges the various efforts to classify in ways that are efficient, effective, and agreeable to all groups of users. If land cover and land uses can be identified by remote methods using aerial photography and satellites, then these ways are more efficient than field surveys of the same area. New technology, such as high-resolution satellite sensors, and new methods, such as more refined algorithms for image interpretation, are providing refined data to better identify the actual cover and apparent use of land, thus effectiveness is improved. However, the closer together and the more vertical the land uses are, the more difficult the task of identification is, and the greater is the need to supplement remotely sensed data with field study (in situ). Thus, a number of land classification methods were developed in order to organize the greatly expanding volume of data on land characteristics in ways useful to different groups. This paper distinguishes two land based classification systems, one developed primarily for remotely sensed data, and the other, a more comprehensive system requiring in situ collection methods. The intent is to look at how the two systems developed and how they can work together so that land based information can be shared among different users and compared over time.

Usability engineering for augmented reality: employing user-based studies to inform design.

PubMed

Gabbard, Joseph L; Swan, J Edward

2008-01-01

A major challenge, and thus opportunity, in the field of human-computer interaction and specifically usability engineering is designing effective user interfaces for emerging technologies that have no established design guidelines or interaction metaphors or introduce completely new ways for users to perceive and interact with technology and the world around them. Clearly, augmented reality is one such emerging technology. We propose a usability engineering approach that employs user-based studies to inform design, by iteratively inserting a series of user-based studies into a traditional usability engineering lifecycle to better inform initial user interface designs. We present an exemplar user-based study conducted to gain insight into how users perceive text in outdoor augmented reality settings and to derive implications for design in outdoor augmented reality. We also describe lessons learned from our experiences conducting user-based studies as part of the design process.

Evaluating user reputation in online rating systems via an iterative group-based ranking method

NASA Astrophysics Data System (ADS)

Gao, Jian; Zhou, Tao

2017-05-01

Reputation is a valuable asset in online social lives and it has drawn increased attention. Due to the existence of noisy ratings and spamming attacks, how to evaluate user reputation in online rating systems is especially significant. However, most of the previous ranking-based methods either follow a debatable assumption or have unsatisfied robustness. In this paper, we propose an iterative group-based ranking method by introducing an iterative reputation-allocation process into the original group-based ranking method. More specifically, the reputation of users is calculated based on the weighted sizes of the user rating groups after grouping all users by their rating similarities, and the high reputation users' ratings have larger weights in dominating the corresponding user rating groups. The reputation of users and the user rating group sizes are iteratively updated until they become stable. Results on two real data sets with artificial spammers suggest that the proposed method has better performance than the state-of-the-art methods and its robustness is considerably improved comparing with the original group-based ranking method. Our work highlights the positive role of considering users' grouping behaviors towards a better online user reputation evaluation.

Digital imaging of root traits (DIRT): a high-throughput computing and collaboration platform for field-based root phenomics.

PubMed

Das, Abhiram; Schneider, Hannah; Burridge, James; Ascanio, Ana Karine Martinez; Wojciechowski, Tobias; Topp, Christopher N; Lynch, Jonathan P; Weitz, Joshua S; Bucksch, Alexander

2015-01-01

Plant root systems are key drivers of plant function and yield. They are also under-explored targets to meet global food and energy demands. Many new technologies have been developed to characterize crop root system architecture (CRSA). These technologies have the potential to accelerate the progress in understanding the genetic control and environmental response of CRSA. Putting this potential into practice requires new methods and algorithms to analyze CRSA in digital images. Most prior approaches have solely focused on the estimation of root traits from images, yet no integrated platform exists that allows easy and intuitive access to trait extraction and analysis methods from images combined with storage solutions linked to metadata. Automated high-throughput phenotyping methods are increasingly used in laboratory-based efforts to link plant genotype with phenotype, whereas similar field-based studies remain predominantly manual low-throughput. Here, we present an open-source phenomics platform "DIRT", as a means to integrate scalable supercomputing architectures into field experiments and analysis pipelines. DIRT is an online platform that enables researchers to store images of plant roots, measure dicot and monocot root traits under field conditions, and share data and results within collaborative teams and the broader community. The DIRT platform seamlessly connects end-users with large-scale compute "commons" enabling the estimation and analysis of root phenotypes from field experiments of unprecedented size. DIRT is an automated high-throughput computing and collaboration platform for field based crop root phenomics. The platform is accessible at http://www.dirt.iplantcollaborative.org/ and hosted on the iPlant cyber-infrastructure using high-throughput grid computing resources of the Texas Advanced Computing Center (TACC). DIRT is a high volume central depository and high-throughput RSA trait computation platform for plant scientists working on crop roots. It enables scientists to store, manage and share crop root images with metadata and compute RSA traits from thousands of images in parallel. It makes high-throughput RSA trait computation available to the community with just a few button clicks. As such it enables plant scientists to spend more time on science rather than on technology. All stored and computed data is easily accessible to the public and broader scientific community. We hope that easy data accessibility will attract new tool developers and spur creative data usage that may even be applied to other fields of science.

Nektar++: An open-source spectral/ hp element framework

NASA Astrophysics Data System (ADS)

Cantwell, C. D.; Moxey, D.; Comerford, A.; Bolis, A.; Rocco, G.; Mengaldo, G.; De Grazia, D.; Yakovlev, S.; Lombard, J.-E.; Ekelschot, D.; Jordi, B.; Xu, H.; Mohamied, Y.; Eskilsson, C.; Nelson, B.; Vos, P.; Biotto, C.; Kirby, R. M.; Sherwin, S. J.

2015-07-01

Nektar++ is an open-source software framework designed to support the development of high-performance scalable solvers for partial differential equations using the spectral/ hp element method. High-order methods are gaining prominence in several engineering and biomedical applications due to their improved accuracy over low-order techniques at reduced computational cost for a given number of degrees of freedom. However, their proliferation is often limited by their complexity, which makes these methods challenging to implement and use. Nektar++ is an initiative to overcome this limitation by encapsulating the mathematical complexities of the underlying method within an efficient C++ framework, making the techniques more accessible to the broader scientific and industrial communities. The software supports a variety of discretisation techniques and implementation strategies, supporting methods research as well as application-focused computation, and the multi-layered structure of the framework allows the user to embrace as much or as little of the complexity as they need. The libraries capture the mathematical constructs of spectral/ hp element methods, while the associated collection of pre-written PDE solvers provides out-of-the-box application-level functionality and a template for users who wish to develop solutions for addressing questions in their own scientific domains.

Sustaining a Community Computing Infrastructure for Online Teacher Professional Development: A Case Study of Designing Tapped In

NASA Astrophysics Data System (ADS)

Farooq, Umer; Schank, Patricia; Harris, Alexandra; Fusco, Judith; Schlager, Mark

Community computing has recently grown to become a major research area in human-computer interaction. One of the objectives of community computing is to support computer-supported cooperative work among distributed collaborators working toward shared professional goals in online communities of practice. A core issue in designing and developing community computing infrastructures — the underlying sociotechnical layer that supports communitarian activities — is sustainability. Many community computing initiatives fail because the underlying infrastructure does not meet end user requirements; the community is unable to maintain a critical mass of users consistently over time; it generates insufficient social capital to support significant contributions by members of the community; or, as typically happens with funded initiatives, financial and human capital resource become unavailable to further maintain the infrastructure. On the basis of more than 9 years of design experience with Tapped In-an online community of practice for education professionals — we present a case study that discusses four design interventions that have sustained the Tapped In infrastructure and its community to date. These interventions represent broader design strategies for developing online environments for professional communities of practice.

Matching the needs of a nation: The strategic roles of indicators for decisionmaking

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peterson, P.J.

Indicators are important tools for communicating and making accessible scientific and technical information to policymakers and the general public. They therefore play an important role in transforming information into action. Worldwide, many initiatives are underway to construct indicators for a variety of purposes, including those for reporting on sustainable development. This paper briefly describes the attempts made so far, but stresses that the users of the indicators should play a greater role in indicator construction. In developing countries, a substantial lack of data has meant that specific policy formulation may develop without adequate technical input. In developed countries also, datamore » gaps may hinder policy formulation, implementation, and evaluation. However, the development of indicators as tools to assist in the management of hazardous wastes and toxic chemicals is still in the early stages of formulation. A more imaginative program of indicators and indices is required, where targets are well defined and the users clearly identified to assist in decision making, especially at the local and national levels. A broader range of pressure indicators, beyond hazardous wastes, is proposed to integrate toxic chemicals, emissions, and environmental and human health impacts. 39 refs., 3 figs.« less

Examining Tensions That Affect the Evaluation of Technology in Health Care: Considerations for System Decision Makers From the Perspective of Industry and Evaluators

PubMed Central

Shaw, James; Wallace, Ross; Bhattacharyya, Onil; Bhatia, R Sacha; Jamieson, Trevor

2017-01-01

Virtual technologies have the potential to mitigate a range of challenges for health care systems. Despite the widespread use of mobile devices in everyday life, they currently have a limited role in health service delivery and clinical care. Efforts to integrate the fast-paced consumer technology market with health care delivery exposes tensions among patients, providers, vendors, evaluators, and system decision makers. This paper explores the key tensions between the high bar for evidence prior to market approval that guides health care regulatory decisions and the “fail fast” reality of the technology industry. We examine three core tensions: balancing user needs versus system needs, rigor versus responsiveness, and the role of pre- versus postmarket evidence generation. We use these to elaborate on the structure and appropriateness of evaluation mechanisms for virtual care solutions. Virtual technologies provide a foundation for personalized, patient-centered medicine on the user side, coupled with a broader understanding of impact on the system side. However, mechanisms for stakeholder discussion are needed to clarify the nature of the health technology marketplace and the drivers of evaluation priorities. PMID:29222075

Geospatial-enabled Data Exploration and Computation through Data Infrastructure Building Blocks

NASA Astrophysics Data System (ADS)

Song, C. X.; Biehl, L. L.; Merwade, V.; Villoria, N.

2015-12-01

Geospatial data are present everywhere today with the proliferation of location-aware computing devices and sensors. This is especially true in the scientific community where large amounts of data are driving research and education activities in many domains. Collaboration over geospatial data, for example, in modeling, data analysis and visualization, must still overcome the barriers of specialized software and expertise among other challenges. The GABBs project aims at enabling broader access to geospatial data exploration and computation by developing spatial data infrastructure building blocks that leverage capabilities of end-to-end application service and virtualized computing framework in HUBzero. Funded by NSF Data Infrastructure Building Blocks (DIBBS) initiative, GABBs provides a geospatial data architecture that integrates spatial data management, mapping and visualization and will make it available as open source. The outcome of the project will enable users to rapidly create tools and share geospatial data and tools on the web for interactive exploration of data without requiring significant software development skills, GIS expertise or IT administrative privileges. This presentation will describe the development of geospatial data infrastructure building blocks and the scientific use cases that help drive the software development, as well as seek feedback from the user communities.

24 CFR 990.255 - Overview.

Code of Federal Regulations, 2010 CFR

2010-04-01

... HOUSING OPERATING FUND PROGRAM Asset Management § 990.255 Overview. (a) PHAs shall manage their properties according to an asset management model, consistent with the management norms in the broader multi-family management industry. PHAs shall also implement project-based management, project-based budgeting, and project...

24 CFR 990.255 - Overview.

Code of Federal Regulations, 2011 CFR

2011-04-01

... HOUSING OPERATING FUND PROGRAM Asset Management § 990.255 Overview. (a) PHAs shall manage their properties according to an asset management model, consistent with the management norms in the broader multi-family management industry. PHAs shall also implement project-based management, project-based budgeting, and project...

Crowd science user contribution patterns and their implications

PubMed Central

Sauermann, Henry; Franzoni, Chiara

2015-01-01

Scientific research performed with the involvement of the broader public (the crowd) attracts increasing attention from scientists and policy makers. A key premise is that project organizers may be able to draw on underused human resources to advance research at relatively low cost. Despite a growing number of examples, systematic research on the effort contributions volunteers are willing to make to crowd science projects is lacking. Analyzing data on seven different projects, we quantify the financial value volunteers can bring by comparing their unpaid contributions with counterfactual costs in traditional or online labor markets. The volume of total contributions is substantial, although some projects are much more successful in attracting effort than others. Moreover, contributions received by projects are very uneven across time—a tendency toward declining activity is interrupted by spikes typically resulting from outreach efforts or media attention. Analyzing user-level data, we find that most contributors participate only once and with little effort, leaving a relatively small share of users who return responsible for most of the work. Although top contributor status is earned primarily through higher levels of effort, top contributors also tend to work faster. This speed advantage develops over multiple sessions, suggesting that it reflects learning rather than inherent differences in skills. Our findings inform recent discussions about potential benefits from crowd science, suggest that involving the crowd may be more effective for some kinds of projects than others, provide guidance for project managers, and raise important questions for future research. PMID:25561529

Heads in the Cloud: A Primer on Neuroimaging Applications of High Performance Computing.

PubMed

Shatil, Anwar S; Younas, Sohail; Pourreza, Hossein; Figley, Chase R

2015-01-01

With larger data sets and more sophisticated analyses, it is becoming increasingly common for neuroimaging researchers to push (or exceed) the limitations of standalone computer workstations. Nonetheless, although high-performance computing platforms such as clusters, grids and clouds are already in routine use by a small handful of neuroimaging researchers to increase their storage and/or computational power, the adoption of such resources by the broader neuroimaging community remains relatively uncommon. Therefore, the goal of the current manuscript is to: 1) inform prospective users about the similarities and differences between computing clusters, grids and clouds; 2) highlight their main advantages; 3) discuss when it may (and may not) be advisable to use them; 4) review some of their potential problems and barriers to access; and finally 5) give a few practical suggestions for how interested new users can start analyzing their neuroimaging data using cloud resources. Although the aim of cloud computing is to hide most of the complexity of the infrastructure management from end-users, we recognize that this can still be an intimidating area for cognitive neuroscientists, psychologists, neurologists, radiologists, and other neuroimaging researchers lacking a strong computational background. Therefore, with this in mind, we have aimed to provide a basic introduction to cloud computing in general (including some of the basic terminology, computer architectures, infrastructure and service models, etc.), a practical overview of the benefits and drawbacks, and a specific focus on how cloud resources can be used for various neuroimaging applications.

Exploring NASA OMI Level 2 Data With Visualization

NASA Technical Reports Server (NTRS)

Wei, Jennifer; Yang, Wenli; Johnson, James; Zhao, Peisheng; Gerasimov, Irina; Pham, Long; Vicente, Gilberto

2014-01-01

Satellite data products are important for a wide variety of applications that can bring far-reaching benefits to the science community and the broader society. These benefits can best be achieved if the satellite data are well utilized and interpreted, such as model inputs from satellite, or extreme events (such as volcano eruptions, dust storms,... etc.). Unfortunately, this is not always the case, despite the abundance and relative maturity of numerous satellite data products provided by NASA and other organizations. Such obstacles may be avoided by allowing users to visualize satellite data as "images", with accurate pixel-level (Level-2) information, including pixel coverage area delineation and science team recommended quality screening for individual geophysical parameters. We present a prototype service from the Goddard Earth Sciences Data and Information Services Center (GES DISC) supporting Aura OMI Level-2 Data with GIS-like capabilities. Functionality includes selecting data sources (e.g., multiple parameters under the same scene, like NO2 and SO2, or the same parameter with different aggregation methods, like NO2 in OMNO2G and OMNO2D products), user-defined area-of-interest and temporal extents, zooming, panning, overlaying, sliding, and data subsetting, reformatting, and reprojection. The system will allow any user-defined portal interface (front-end) to connect to our backend server with OGC standard-compliant Web Mapping Service (WMS) and Web Coverage Service (WCS) calls. This back-end service should greatly enhance its expandability to integrate additional outside data/map sources.

Exploring NASA OMI Level 2 Data With Visualization

NASA Technical Reports Server (NTRS)

Wei, Jennifer C.; Yang, Wenli; Johnson, James; Zhao, Peisheng; Gerasimov, Irina; Pham, Long; Vincente, Gilbert

2014-01-01

Satellite data products are important for a wide variety of applications that can bring far-reaching benefits to the science community and the broader society. These benefits can best be achieved if the satellite data are well utilized and interpreted, such as model inputs from satellite, or extreme events (such as volcano eruptions, dust storms, etc.).Unfortunately, this is not always the case, despite the abundance and relative maturity of numerous satellite data products provided by NASA and other organizations. Such obstacles may be avoided by allowing users to visualize satellite data as images, with accurate pixel-level (Level-2) information, including pixel coverage area delineation and science team recommended quality screening for individual geophysical parameters. We present a prototype service from the Goddard Earth Sciences Data and Information Services Center (GES DISC) supporting Aura OMI Level-2 Data with GIS-like capabilities. Functionality includes selecting data sources (e.g., multiple parameters under the same scene, like NO2 and SO2, or the same parameter with different aggregation methods, like NO2 in OMNO2G and OMNO2D products), user-defined area-of-interest and temporal extents, zooming, panning, overlaying, sliding, and data subsetting, reformatting, and reprojection. The system will allow any user-defined portal interface (front-end) to connect to our backend server with OGC standard-compliant Web Mapping Service (WMS) and Web Coverage Service (WCS) calls. This back-end service should greatly enhance its expandability to integrate additional outside data-map sources.

Acupuncture, chiropractic and osteopathy use in Australia: a national population survey

PubMed Central

Xue, Charlie CL; Zhang, Anthony L; Lin, Vivian; Myers, Ray; Polus, Barbara; Story, David F

2008-01-01

Background There have been no published national studies on the use in Australia of the manipulative therapies, acupuncture, chiropractic or osteopathy, or on matters including the purposes for which these therapies are used, treatment outcomes and the socio-demographic characteristics of users. Methods This study on the three manipulative therapies was a component of a broader investigation on the use of complementary and alternative therapies. For this we conducted a cross-sectional, population survey on a representative sample of 1,067 adults from the six states and two territories of Australia in 2005 by computer-assisted telephone interviews. The sample was recruited by random digit dialling. Results Over a 12-month period, approximately one in four adult Australians used either acupuncture (9.2%), chiropractic (16.1%) or osteopathy (4.6%) at least once. It is estimated that, adult Australians made 32.3 million visits to acupuncturists, chiropractors and osteopaths, incurring personal expenditure estimated to be A$1.58 billion in total. The most common conditions treated were back pain and related problems and over 90% of the users of each therapy considered their treatment to be very or somewhat helpful. Adverse events are reported. Nearly one fifth of users were referred to manipulative therapy practitioners by medical practitioners. Conclusion There is substantial use of manipulative therapies by adult Australians, especially for back-related problems. Treatments incur considerable personal expenditure. In general, patient experience is positive. Referral by medical practitioners is a major determinant of use of these manipulative therapies. PMID:18377663

Crowd science user contribution patterns and their implications

NASA Astrophysics Data System (ADS)

Sauermann, Henry; Franzoni, Chiara

2015-01-01

Scientific research performed with the involvement of the broader public (the crowd) attracts increasing attention from scientists and policy makers. A key premise is that project organizers may be able to draw on underused human resources to advance research at relatively low cost. Despite a growing number of examples, systematic research on the effort contributions volunteers are willing to make to crowd science projects is lacking. Analyzing data on seven different projects, we quantify the financial value volunteers can bring by comparing their unpaid contributions with counterfactual costs in traditional or online labor markets. The volume of total contributions is substantial, although some projects are much more successful in attracting effort than others. Moreover, contributions received by projects are very uneven across time-a tendency toward declining activity is interrupted by spikes typically resulting from outreach efforts or media attention. Analyzing user-level data, we find that most contributors participate only once and with little effort, leaving a relatively small share of users who return responsible for most of the work. Although top contributor status is earned primarily through higher levels of effort, top contributors also tend to work faster. This speed advantage develops over multiple sessions, suggesting that it reflects learning rather than inherent differences in skills. Our findings inform recent discussions about potential benefits from crowd science, suggest that involving the crowd may be more effective for some kinds of projects than others, provide guidance for project managers, and raise important questions for future research.

Crowd science user contribution patterns and their implications.

PubMed

Sauermann, Henry; Franzoni, Chiara

2015-01-20

Scientific research performed with the involvement of the broader public (the crowd) attracts increasing attention from scientists and policy makers. A key premise is that project organizers may be able to draw on underused human resources to advance research at relatively low cost. Despite a growing number of examples, systematic research on the effort contributions volunteers are willing to make to crowd science projects is lacking. Analyzing data on seven different projects, we quantify the financial value volunteers can bring by comparing their unpaid contributions with counterfactual costs in traditional or online labor markets. The volume of total contributions is substantial, although some projects are much more successful in attracting effort than others. Moreover, contributions received by projects are very uneven across time--a tendency toward declining activity is interrupted by spikes typically resulting from outreach efforts or media attention. Analyzing user-level data, we find that most contributors participate only once and with little effort, leaving a relatively small share of users who return responsible for most of the work. Although top contributor status is earned primarily through higher levels of effort, top contributors also tend to work faster. This speed advantage develops over multiple sessions, suggesting that it reflects learning rather than inherent differences in skills. Our findings inform recent discussions about potential benefits from crowd science, suggest that involving the crowd may be more effective for some kinds of projects than others, provide guidance for project managers, and raise important questions for future research.

Heads in the Cloud: A Primer on Neuroimaging Applications of High Performance Computing

PubMed Central

Shatil, Anwar S.; Younas, Sohail; Pourreza, Hossein; Figley, Chase R.

2015-01-01

With larger data sets and more sophisticated analyses, it is becoming increasingly common for neuroimaging researchers to push (or exceed) the limitations of standalone computer workstations. Nonetheless, although high-performance computing platforms such as clusters, grids and clouds are already in routine use by a small handful of neuroimaging researchers to increase their storage and/or computational power, the adoption of such resources by the broader neuroimaging community remains relatively uncommon. Therefore, the goal of the current manuscript is to: 1) inform prospective users about the similarities and differences between computing clusters, grids and clouds; 2) highlight their main advantages; 3) discuss when it may (and may not) be advisable to use them; 4) review some of their potential problems and barriers to access; and finally 5) give a few practical suggestions for how interested new users can start analyzing their neuroimaging data using cloud resources. Although the aim of cloud computing is to hide most of the complexity of the infrastructure management from end-users, we recognize that this can still be an intimidating area for cognitive neuroscientists, psychologists, neurologists, radiologists, and other neuroimaging researchers lacking a strong computational background. Therefore, with this in mind, we have aimed to provide a basic introduction to cloud computing in general (including some of the basic terminology, computer architectures, infrastructure and service models, etc.), a practical overview of the benefits and drawbacks, and a specific focus on how cloud resources can be used for various neuroimaging applications. PMID:27279746

Future View: Web Navigation based on Learning User's Browsing Strategy

NASA Astrophysics Data System (ADS)

Nagino, Norikatsu; Yamada, Seiji

In this paper, we propose a Future View system that assists user's usual Web browsing. The Future View will prefetch Web pages based on user's browsing strategies and present them to a user in order to assist Web browsing. To learn user's browsing strategy, the Future View uses two types of learning classifier systems: a content-based classifier system for contents change patterns and an action-based classifier system for user's action patterns. The results of learning is applied to crawling by Web robots, and the gathered Web pages are presented to a user through a Web browser interface. We experimentally show effectiveness of navigation using the Future View.

Promzea: a pipeline for discovery of co-regulatory motifs in maize and other plant species and its application to the anthocyanin and phlobaphene biosynthetic pathways and the Maize Development Atlas.

PubMed

Liseron-Monfils, Christophe; Lewis, Tim; Ashlock, Daniel; McNicholas, Paul D; Fauteux, François; Strömvik, Martina; Raizada, Manish N

2013-03-15

The discovery of genetic networks and cis-acting DNA motifs underlying their regulation is a major objective of transcriptome studies. The recent release of the maize genome (Zea mays L.) has facilitated in silico searches for regulatory motifs. Several algorithms exist to predict cis-acting elements, but none have been adapted for maize. A benchmark data set was used to evaluate the accuracy of three motif discovery programs: BioProspector, Weeder and MEME. Analysis showed that each motif discovery tool had limited accuracy and appeared to retrieve a distinct set of motifs. Therefore, using the benchmark, statistical filters were optimized to reduce the false discovery ratio, and then remaining motifs from all programs were combined to improve motif prediction. These principles were integrated into a user-friendly pipeline for motif discovery in maize called Promzea, available at http://www.promzea.org and on the Discovery Environment of the iPlant Collaborative website. Promzea was subsequently expanded to include rice and Arabidopsis. Within Promzea, a user enters cDNA sequences or gene IDs; corresponding upstream sequences are retrieved from the maize genome. Predicted motifs are filtered, combined and ranked. Promzea searches the chosen plant genome for genes containing each candidate motif, providing the user with the gene list and corresponding gene annotations. Promzea was validated in silico using a benchmark data set: the Promzea pipeline showed a 22% increase in nucleotide sensitivity compared to the best standalone program tool, Weeder, with equivalent nucleotide specificity. Promzea was also validated by its ability to retrieve the experimentally defined binding sites of transcription factors that regulate the maize anthocyanin and phlobaphene biosynthetic pathways. Promzea predicted additional promoter motifs, and genome-wide motif searches by Promzea identified 127 non-anthocyanin/phlobaphene genes that each contained all five predicted promoter motifs in their promoters, perhaps uncovering a broader co-regulated gene network. Promzea was also tested against tissue-specific microarray data from maize. An online tool customized for promoter motif discovery in plants has been generated called Promzea. Promzea was validated in silico by its ability to retrieve benchmark motifs and experimentally defined motifs and was tested using tissue-specific microarray data. Promzea predicted broader networks of gene regulation associated with the historic anthocyanin and phlobaphene biosynthetic pathways. Promzea is a new bioinformatics tool for understanding transcriptional gene regulation in maize and has been expanded to include rice and Arabidopsis.

AUI&GIV: Recommendation with Asymmetric User Influence and Global Importance Value.

PubMed

Zhao, Zhi-Lin; Wang, Chang-Dong; Lai, Jian-Huang

2016-01-01

The user-based collaborative filtering (CF) algorithm is one of the most popular approaches for making recommendation. Despite its success, the traditional user-based CF algorithm suffers one serious problem that it only measures the influence between two users based on their symmetric similarities calculated by their consumption histories. It means that, for a pair of users, the influences on each other are the same, which however may not be true. Intuitively, an expert may have an impact on a novice user but a novice user may not affect an expert at all. Besides, each user may possess a global importance factor that affects his/her influence to the remaining users. To this end, in this paper, we propose an asymmetric user influence model to measure the directed influence between two users and adopt the PageRank algorithm to calculate the global importance value of each user. And then the directed influence values and the global importance values are integrated to deduce the final influence values between two users. Finally, we use the final influence values to improve the performance of the traditional user-based CF algorithm. Extensive experiments have been conducted, the results of which have confirmed that both the asymmetric user influence model and global importance value play key roles in improving recommendation accuracy, and hence the proposed method significantly outperforms the existing recommendation algorithms, in particular the user-based CF algorithm on the datasets of high rating density.

AUI&GIV: Recommendation with Asymmetric User Influence and Global Importance Value

PubMed Central

Zhao, Zhi-Lin; Wang, Chang-Dong; Lai, Jian-Huang

2016-01-01

The user-based collaborative filtering (CF) algorithm is one of the most popular approaches for making recommendation. Despite its success, the traditional user-based CF algorithm suffers one serious problem that it only measures the influence between two users based on their symmetric similarities calculated by their consumption histories. It means that, for a pair of users, the influences on each other are the same, which however may not be true. Intuitively, an expert may have an impact on a novice user but a novice user may not affect an expert at all. Besides, each user may possess a global importance factor that affects his/her influence to the remaining users. To this end, in this paper, we propose an asymmetric user influence model to measure the directed influence between two users and adopt the PageRank algorithm to calculate the global importance value of each user. And then the directed influence values and the global importance values are integrated to deduce the final influence values between two users. Finally, we use the final influence values to improve the performance of the traditional user-based CF algorithm. Extensive experiments have been conducted, the results of which have confirmed that both the asymmetric user influence model and global importance value play key roles in improving recommendation accuracy, and hence the proposed method significantly outperforms the existing recommendation algorithms, in particular the user-based CF algorithm on the datasets of high rating density. PMID:26828803

A nudge too far? A nudge at all? On paying people to be healthy.

PubMed

Oliver, Adam

2012-01-01

Paying people to engage in healthy behaviours, such as adhering to medications, quitting smoking and losing weight, has been linked to the nudge agenda. However, "user financial incentives" (UFI) can only be classified as nudges if they meet a strict set of requirements. Perhaps more importantly, UFI have thus far showed some promise only for "single shot" behaviour change, such as that associated with many acts of medical adherence, and have been generally unfruitful in effecting the sustained behaviour change that is necessary to influence broader lifestyle decisions, such as those associated with smoking and weight. Possibly more importantly still, the legitimacy of government-sponsored interventions intended to influence directly broad lifestyle behaviours, providing that those behaviours are not unduly harming others, ought to be scrutinized

Assistive Technology for an Inclusive Society for People with Intellectual Disability.

PubMed

Owuor, John; Larkan, Fiona

2017-01-01

People with intellectual disability (ID), are some of the most stigmatized and marginalized social groups. Ongoing global initiatives such as the United Nations Convention on the Rights of Persons with Disabilities (UNCPD) and Strategic Development Goals (SDGs) aim to accelerate their inclusion into the society. In many high-income countries, deinstitutionalization of care for people with ID forms part of the broader social inclusion agenda for people with ID into the society. Access to appropriate assistive technology (AT) can mediate the ongoing normalization/inclusion efforts for people with ID. AT can enable users with ID to access societal processes such as education, employment, socialization or independent living. Effective use of AT can also enhance the formation and/or maintenance of interpersonal relationships by people with ID, thus promote their social support.

A situational analysis of HIV/AIDS-related discrimination in Hanoi, Vietnam.

PubMed

Khoat, D V; Hong, L D; An, C Q; Ngu, D; Reidpath, D D

2005-07-01

The laws in Vietnam provide a framework within which one may judge the nature and type of health care-related discrimination to which people living with HIV (PLWHA) are subject. Despite the existence of stringent legislation protecting the rights of PLWHA, this study found that, in practice, PLWHA experienced significant structural discrimination in their daily lives. The discrimination experienced by PLWHA was exacerbated by the fact that, historically, HIV is associated with high-risk, marginalized groups such as drug users and sex workers. In the health care sector, discriminatory practices (for instance, refusal to treat), differential treatment and non-confidentiality were frequent. For the development of successful prevention and treatment strategies, a mutually desirable and equitable balance must be achieved between individual rights and needs and individual obligations to the broader society.

Emerging issues and current trends in assistive technology use 2007-2010: practising, assisting and enabling learning for all.

PubMed

Abbott, Chris; Brown, David; Evett, Lindsay; Standen, Penny

2014-11-01

Following an earlier review in 2007, a further review of the academic literature relating to the uses of assistive technology (AT) by children and young people was completed, covering the period 2007-2011. As in the earlier review, a tripartite taxonomy: technology uses to train or practise, technology uses to assist learning and technology uses to enable learning, was used in order to structure the findings. The key markers for research in this field and during these three years were user involvement, AT on mobile mainstream devices, the visibility of AT, technology for interaction and collaboration, new and developing interfaces and inclusive design principles. The paper concludes by locating these developments within the broader framework of the Digital Divide.

tsiR: An R package for time-series Susceptible-Infected-Recovered models of epidemics.

PubMed

Becker, Alexander D; Grenfell, Bryan T

2017-01-01

tsiR is an open source software package implemented in the R programming language designed to analyze infectious disease time-series data. The software extends a well-studied and widely-applied algorithm, the time-series Susceptible-Infected-Recovered (TSIR) model, to infer parameters from incidence data, such as contact seasonality, and to forward simulate the underlying mechanistic model. The tsiR package aggregates a number of different fitting features previously described in the literature in a user-friendly way, providing support for their broader adoption in infectious disease research. Also included in tsiR are a number of diagnostic tools to assess the fit of the TSIR model. This package should be useful for researchers analyzing incidence data for fully-immunizing infectious diseases.

Metabolomics and Epidemiology Working Group

Cancer.gov

The Metabolomics and Epidemiology (MetEpi) Working Group promotes metabolomics analyses in population-based studies, as well as advancement in the field of metabolomics for broader biomedical and public health research.

Graphical User Interfaces and Library Systems: End-User Reactions.

ERIC Educational Resources Information Center

Zorn, Margaret; Marshall, Lucy

1995-01-01

Describes a study by Parke-Davis Pharmaceutical Research Library to determine user satisfaction with the graphical user interface-based (GUI) Dynix Marquis compared with the text-based Dynix Classic Online Public Access Catalog (OPAC). Results show that the GUI-based OPAC was preferred by endusers over the text-based OPAC. (eight references) (DGM)

Presenting Bionic: Broader Impacts and Outreach Network for Institutional Collaboration

NASA Astrophysics Data System (ADS)

Storm, K.

2014-12-01

Broader Impact plans are required of all NSF proposals. In 2011 the National Science Board, which oversees NSF, reconfirmed NSF's commitment to Broader Impacts in its task force report on the merit review system. At many institutions there are professionals that focus their work on supporting the Broader Impact work of researchers. This session will share the Broader Impacts and Outreach Network for Institutional Collaboration (BIONIC) plan to create a professional network of individuals and offices committed to planning and carrying out effective Broader Impact programming. BIONIC is an NSF Research Coordination Network that is recommended for funding through the Biology Directorate. In this session we will share the goals of BIONIC, and the progress to date in reaching those goals (of which one aspect is the curating of effective Broader Impact initiatives).

Demographic-Based Content Analysis of Web-Based Health-Related Social Media.

PubMed

Sadah, Shouq A; Shahbazi, Moloud; Wiley, Matthew T; Hristidis, Vagelis

2016-06-13

An increasing number of patients from diverse demographic groups share and search for health-related information on Web-based social media. However, little is known about the content of the posted information with respect to the users' demographics. The aims of this study were to analyze the content of Web-based health-related social media based on users' demographics to identify which health topics are discussed in which social media by which demographic groups and to help guide educational and research activities. We analyze 3 different types of health-related social media: (1) general Web-based social networks Twitter and Google+; (2) drug review websites; and (3) health Web forums, with a total of about 6 million users and 20 million posts. We analyzed the content of these posts based on the demographic group of their authors, in terms of sentiment and emotion, top distinctive terms, and top medical concepts. The results of this study are: (1) Pregnancy is the dominant topic for female users in drug review websites and health Web forums, whereas for male users, it is cardiac problems, HIV, and back pain, but this is not the case for Twitter; (2) younger users (0-17 years) mainly talk about attention-deficit hyperactivity disorder (ADHD) and depression-related drugs, users aged 35-44 years discuss about multiple sclerosis (MS) drugs, and middle-aged users (45-64 years) talk about alcohol and smoking; (3) users from the Northeast United States talk about physical disorders, whereas users from the West United States talk about mental disorders and addictive behaviors; (4) Users with higher writing level express less anger in their posts. We studied the popular topics and the sentiment based on users' demographics in Web-based health-related social media. Our results provide valuable information, which can help create targeted and effective educational campaigns and guide experts to reach the right users on Web-based social chatter.

Place-Based Design: An Instructional Design Theory for Supporting Community-Based Inquiry and Design Projects

ERIC Educational Resources Information Center

Mathews, James M.

2013-01-01

Place-based education has been forwarded as a pedagogical approach that has the potential to contextualize learning, increase student engagement, and strengthen the relationship between schools and the broader community. Despite this promise, however, many teachers struggle to develop learning experiences that incorporate the key components of…

Community Involvement: A Case Study of the Education Resource Center.

ERIC Educational Resources Information Center

Wilson, Stephen; And Others

The Education Resource Center (ERC) is a community-based teachers' resource center located in Chicago (Illinois). Its conceptual base is broader than that of a typical teachers center as ERC represents a community-based social movement with a wider orientation than teacher training. ERC's policy board reflects community organizations and the…

Evidence-Based Practice: A Framework for Making Effective Decisions

ERIC Educational Resources Information Center

Spencer, Trina D.; Detrich, Ronnie; Slocum, Timothy A.

2012-01-01

The research to practice gap in education has been a long-standing concern. The enactment of No Child Left Behind brought increased emphasis on the value of using scientifically based instructional practices to improve educational outcomes. It also brought education into the broader evidence-based practice movement that started in medicine and has…

Bundling occupational safety with harm reduction information as a feasible method for improving police receptiveness to syringe access programs: evidence from three U.S. cities

PubMed Central

Davis, Corey S; Beletsky, Leo

2009-01-01

Introduction In light of overwhelming evidence that access to sterile injection equipment reduces incidence of injection-attributable bloodborne disease without encouraging drug use, many localities have authorized sterile syringe access programs (SAPs), including syringe exchange and pharmacy-based initiatives. Even where such interventions are clearly legal, many law enforcement officers are unaware of the public health benefits and legal status of these programs and may continue to treat the possession of injection equipment as illegal and program participation as a marker of illegal behavior. Law enforcement practice can impede SAP utilization and may increase the risk of needlestick injury (NSI) among law enforcement personnel. Many SAPs conduct little or no outreach to law enforcement, in part because they perceive law enforcement actors as unreceptive to health-promotion programs targeting drug users. Case description We report on a brief training intervention for law enforcement personnel designed to increase officer knowledge of and positive attitudes towards SAPs by bundling content that addresses officer concerns about infectious disease and occupational safety with information about the legality and public health benefits of these programs. Pilot trainings using this bundled curriculum were conducted with approximately 600 officers in three US cities. Discussion and evaluation Law enforcement officers were generally receptive to receiving information about SAPs through the bundled curriculum. The trainings led to better communication and collaboration between SAP and law enforcement personnel, providing a valuable platform for better harmonization of law enforcement and public health activities targeting injection drug users. Conclusion The experience in these three cities suggests that a harm reduction training curriculum that bundles strategies for increasing officer occupational safety with information about the legality and public health benefits of SAPs can be well received by law enforcement personnel and can lead to better communication and collaboration between law enforcement and harm reduction actors. Further study is indicated to assess whether such a bundled curriculum is effective in changing officer attitudes and beliefs and reducing health risks to officers and injection drug users, as well as broader benefits to the community at large. PMID:19602236

The research on user behavior evaluation method for network state

NASA Astrophysics Data System (ADS)

Zhang, Chengyuan; Xu, Haishui

2017-08-01

Based on the correlation between user behavior and network running state, this paper proposes a method of user behavior evaluation based on network state. Based on the analysis and evaluation methods in other fields of study, we introduce the theory and tools of data mining. Based on the network status information provided by the trusted network view, the user behavior data and the network state data are analysed. Finally, we construct the user behavior evaluation index and weight, and on this basis, we can accurately quantify the influence degree of the specific behavior of different users on the change of network running state, so as to provide the basis for user behavior control decision.

24 CFR 58.15 - Tiering.

Code of Federal Regulations, 2012 CFR

2012-04-01

... the issues addressed in the broader review. The broader review should identify and evaluate those... consideration. The broader review should also establish the policy, standard or process to be followed in the site specific review. The Finding of No Significant Impact (FONSI) with respect to the broader...

24 CFR 58.15 - Tiering.

Code of Federal Regulations, 2011 CFR

2011-04-01

... the issues addressed in the broader review. The broader review should identify and evaluate those... consideration. The broader review should also establish the policy, standard or process to be followed in the site specific review. The Finding of No Significant Impact (FONSI) with respect to the broader...

24 CFR 58.15 - Tiering.

Code of Federal Regulations, 2014 CFR

2014-04-01

... the issues addressed in the broader review. The broader review should identify and evaluate those... consideration. The broader review should also establish the policy, standard or process to be followed in the site specific review. The Finding of No Significant Impact (FONSI) with respect to the broader...

24 CFR 58.15 - Tiering.

Code of Federal Regulations, 2013 CFR

2013-04-01

... the issues addressed in the broader review. The broader review should identify and evaluate those... consideration. The broader review should also establish the policy, standard or process to be followed in the site specific review. The Finding of No Significant Impact (FONSI) with respect to the broader...

24 CFR 58.15 - Tiering.

Code of Federal Regulations, 2010 CFR

2010-04-01

... the issues addressed in the broader review. The broader review should identify and evaluate those... consideration. The broader review should also establish the policy, standard or process to be followed in the site specific review. The Finding of No Significant Impact (FONSI) with respect to the broader...

Enabling User to User Interactions in Web Lectures with History-Aware User Awareness

ERIC Educational Resources Information Center

Ketterl, Markus; Mertens, Robert; Wiesen, Christoph; Vornberger, Oliver

2011-01-01

Purpose: The purpose of this paper is to present a user interface for web lectures for engaging with other users while working with video based learning content. The application allows its users to ask questions about the content and to get answers from those users that currently online are more familiar with it. The filtering is based on the…

ConformRank: A conformity-based rank for finding top-k influential users

NASA Astrophysics Data System (ADS)

Wang, Qiyao; Jin, Yuehui; Cheng, Shiduan; Yang, Tan

2017-05-01

Finding influential users is a hot topic in social networks. For example, advertisers identify influential users to make a successful campaign. Retweeters forward messages from original users, who originally publish messages. This action is referred to as retweeting. Retweeting behaviors generate influence. Original users have influence on retweeters. Whether retweeters keep the same sentiment as original users is taken into consideration in this study. Influence is calculated based on conformity from emotional perspective after retweeting. A conformity-based algorithm, called ConformRank, is proposed to find top-k influential users, who make the most users keep the same sentiment after retweeting messages. Emotional conformity is introduced to denote how users conform to original users from the emotional perspective. Conforming weights are introduced to denote how two users keep the same sentiment after retweeting messages. Emotional conformity is applied for users and conforming weights are used for relations. Experiments were conducted on Sina Weibo. Experimental results show that users have larger influence when they publish positive messages.

A user credit assessment model based on clustering ensemble for broadband network new media service supervision

NASA Astrophysics Data System (ADS)

Liu, Fang; Cao, San-xing; Lu, Rui

2012-04-01

This paper proposes a user credit assessment model based on clustering ensemble aiming to solve the problem that users illegally spread pirated and pornographic media contents within the user self-service oriented broadband network new media platforms. Its idea is to do the new media user credit assessment by establishing indices system based on user credit behaviors, and the illegal users could be found according to the credit assessment results, thus to curb the bad videos and audios transmitted on the network. The user credit assessment model based on clustering ensemble proposed by this paper which integrates the advantages that swarm intelligence clustering is suitable for user credit behavior analysis and K-means clustering could eliminate the scattered users existed in the result of swarm intelligence clustering, thus to realize all the users' credit classification automatically. The model's effective verification experiments are accomplished which are based on standard credit application dataset in UCI machine learning repository, and the statistical results of a comparative experiment with a single model of swarm intelligence clustering indicates this clustering ensemble model has a stronger creditworthiness distinguishing ability, especially in the aspect of predicting to find user clusters with the best credit and worst credit, which will facilitate the operators to take incentive measures or punitive measures accurately. Besides, compared with the experimental results of Logistic regression based model under the same conditions, this clustering ensemble model is robustness and has better prediction accuracy.

Long Duration Exposure Facility Mini-Data Base User`s Guide: Macintosh version. (Diskette)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bohnhoff-Hlavacek, G.; Pippin, H.G.; Dursch, H.W.

1995-04-01

One of the objectives of the LDEF Special Investigation Group (SIG) was to develop a LDEF data base that identifies the experiment objectives and hardware flown, summarizes results and conclusions, and provides a system analysis overview, including spacecraft design guidelines and space environmental effects. Compiling the information into an easily accessible data base format, and making it available to the space community was a major task accomplished by the System and Materials SIG effort beginning in 1981. Included in this document is a short user`s manual for the LDEF Mini-Data Bases. The user`s manual contains pertinent examples from the datamore » base on specifically how to access and work with the LDEF information. Accompanying this document are the mini-data bases on disk.« less

Inquiry and Industry Inspired Laboratories: The Impact on Students' Perceptions of Skill Development and Engagements

ERIC Educational Resources Information Center

George-Williams, Stephen R.; Soo, Jue T.; Ziebell, Angela L.; Thompson, Christopher D.; Overton, Tina L.

2018-01-01

Many examples exist in the chemical education literature of individual experiments, whole courses or even entire year levels that have been completely renewed under the tenets of context-based, inquiry-based or problem-based learning. The benefits of these changes are well documented and include higher student engagement, broader skill development…

On Educational Advocacy and Cultural Work: Situating Community-Based Youth Work[ers] in Broader Educational Discourse

ERIC Educational Resources Information Center

Baldridge, Biana J.

2018-01-01

Background/Context: The current educational market nestled in neoliberal and market-based reform efforts has shifted the nature of public education. Community-based educational spaces are also shaped within this context. As such, given the political and educational climate youth workers are situated in, their role as advocates, cultural workers,…

Challenge-Based Instruction: The VaNTH Biomechanics Learning Modules

ERIC Educational Resources Information Center

Barr, Ronald E.; Pandy, Marcus G.; Petrosino, Anthony J.; Roselli, Robert J.; Brophy, Sean; Freeman, Robert A.

2007-01-01

This paper presents the methodology and results of teaching an entire engineering course using challenge-based instruction. The challenges consisted of eight biomechanics multimedia learning modules developed by the authors as part of a broader NSF educational coalition. The biomechanics modules were presented in an undergraduate mechanical…

An "Heretical" Method for Teaching Foreign Languages.

ERIC Educational Resources Information Center

Bar-Lev, Zev

This article presents an output-printed, lexically-based communicative teaching method. Specially designed to impart spontaneous speaking abilities for special students, it is a possible solution to broader problems of foreign language teaching. It is based on the assumption that acquisition-sequence is crucial to successful classroom study, but…

Understanding Motivation for Study: Human Capital or Human Capability?

ERIC Educational Resources Information Center

Fredman, Nick

2014-01-01

Much research into the reasons students undertake tertiary study is at least implicitly based on rational choice theory: students calculate costs in order to maximize direct individual gain. The policy emphasis on pathways has somewhat broader bases including social inclusion as well as economic productivity, but narrowly focuses on institutional…

The impact of fuels on aircraft technology through the year 2000

NASA Technical Reports Server (NTRS)

Grobman, J.; Reck, G. M.

1980-01-01

In the future, it may be necessary to use jet fuels with a broader range of properties in order to insure a more flexible and reliable supply and to minimize energy consumption and processing costs at the refinery. This paper describes research being conducted to (1) determine the potential range of properties for future jet fuels, (2) establish a data base of fuel property effects on propulsion system components, (3) evolve and evaluate advanced component technology that would permit the use of broader property fuels and (4) identify technical and economic trade-offs within the overall fuel production-air transportation system associated with variations in fuel properties.

Leaf-GP: an open and automated software application for measuring growth phenotypes for arabidopsis and wheat.

PubMed

Zhou, Ji; Applegate, Christopher; Alonso, Albor Dobon; Reynolds, Daniel; Orford, Simon; Mackiewicz, Michal; Griffiths, Simon; Penfield, Steven; Pullen, Nick

2017-01-01

Plants demonstrate dynamic growth phenotypes that are determined by genetic and environmental factors. Phenotypic analysis of growth features over time is a key approach to understand how plants interact with environmental change as well as respond to different treatments. Although the importance of measuring dynamic growth traits is widely recognised, available open software tools are limited in terms of batch image processing, multiple traits analyses, software usability and cross-referencing results between experiments, making automated phenotypic analysis problematic. Here, we present Leaf-GP (Growth Phenotypes), an easy-to-use and open software application that can be executed on different computing platforms. To facilitate diverse scientific communities, we provide three software versions, including a graphic user interface (GUI) for personal computer (PC) users, a command-line interface for high-performance computer (HPC) users, and a well-commented interactive Jupyter Notebook (also known as the iPython Notebook) for computational biologists and computer scientists. The software is capable of extracting multiple growth traits automatically from large image datasets. We have utilised it in Arabidopsis thaliana and wheat ( Triticum aestivum ) growth studies at the Norwich Research Park (NRP, UK). By quantifying a number of growth phenotypes over time, we have identified diverse plant growth patterns between different genotypes under several experimental conditions. As Leaf-GP has been evaluated with noisy image series acquired by different imaging devices (e.g. smartphones and digital cameras) and still produced reliable biological outputs, we therefore believe that our automated analysis workflow and customised computer vision based feature extraction software implementation can facilitate a broader plant research community for their growth and development studies. Furthermore, because we implemented Leaf-GP based on open Python-based computer vision, image analysis and machine learning libraries, we believe that our software not only can contribute to biological research, but also demonstrates how to utilise existing open numeric and scientific libraries (e.g. Scikit-image, OpenCV, SciPy and Scikit-learn) to build sound plant phenomics analytic solutions, in a efficient and effective way. Leaf-GP is a sophisticated software application that provides three approaches to quantify growth phenotypes from large image series. We demonstrate its usefulness and high accuracy based on two biological applications: (1) the quantification of growth traits for Arabidopsis genotypes under two temperature conditions; and (2) measuring wheat growth in the glasshouse over time. The software is easy-to-use and cross-platform, which can be executed on Mac OS, Windows and HPC, with open Python-based scientific libraries preinstalled. Our work presents the advancement of how to integrate computer vision, image analysis, machine learning and software engineering in plant phenomics software implementation. To serve the plant research community, our modulated source code, detailed comments, executables (.exe for Windows; .app for Mac), and experimental results are freely available at https://github.com/Crop-Phenomics-Group/Leaf-GP/releases.

Long Duration Exposure Facility mini-data base user`s guide: IBM-compatible PC computer version. (Diskette)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bohnhoff-Hlavacek, G.; Pippin, G.; Dursch, H.

1995-04-01

One of the objectives of the LDEF Special Investigation Group (SIG) was to develop a LDEF data base that identifies the experiment objectives and hardware flown, summarizes results and conclusions, and provides a system analysis overview which would include spacecraft design guidelines and space environmental effects. Compiling this information into an easily accessible data base format and making it available to the space community was a major task accomplished by the System and Materials SIG effort beginning in 1991. Included in this document is a short user`s manual for the LDEF Mini-Data Bases. The user`s manual contains pertinent examples frommore » the data base on specifically how to access and work with the LDEF information. Accompanying this document are the mini-data bases on disk.« less

Consumer willingness to invest money and time for benefits of lifestyle behaviour change: an application of the contingent valuation method.

PubMed

Alayli-Goebbels, Adrienne F G; van Exel, Job; Ament, André J H A; de Vries, Nanne K; Bot, Sandra D M; Severens, Johan L

2015-12-01

To use contingent valuation (CV) to derive individual consumer values for both health and broader benefits of a public-health intervention directed at lifestyle behaviour change (LBC) and to examine the feasibility and validity of the method. Participants of a lifestyle intervention trial (n = 515) were invited to complete an online CV survey. Respondents (n = 312) expressed willingness to invest money and time for changes in life expectancy, health-related quality of life (HRQOL) and broader quality of life aspects. Internal validity was tested for by exploring associations between explanatory variables (i.e. income, paid work, experience and risk factors for cardiovascular diseases) and willingness to invest, and by examining ordering effects and respondents' sensitivity to the scope of the benefits. The majority of respondents (94.3%) attached value to benefits of LBC, and 87.4% were willing to invest both money and time. Respondents were willing to invest more for improvements in HRQOL (€42/month; 3 h/week) and broader quality of life aspects (€40/month; 2.6 h/week) than for improvements in life expectancy (€24/month; 2 h/week). Protest answers were limited (3%) and findings regarding internal validity were mixed. The importance of broader quality of life outcomes to consumers suggests that these outcomes are relevant to be considered in the decision making. Our research showed that CV is a feasible method to value both health and broader outcomes of LBC, but generalizability to other areas of public health still needs to be examined. Mixed evidence regarding internal validity pleads for caution to use CV as only the base for decision making. © 2014 John Wiley & Sons Ltd.

Supporting dynamic change detection: using the right tool for the task.

PubMed

Vallières, Benoît R; Hodgetts, Helen M; Vachon, François; Tremblay, Sébastien

2016-01-01

Detecting task-relevant changes in a visual scene is necessary for successfully monitoring and managing dynamic command and control situations. Change blindness-the failure to notice visual changes-is an important source of human error. Change History EXplicit (CHEX) is a tool developed to aid change detection and maintain situation awareness; and in the current study we test the generality of its ability to facilitate the detection of changes when this subtask is embedded within a broader dynamic decision-making task. A multitasking air-warfare simulation required participants to perform radar-based subtasks, for which change detection was a necessary aspect of the higher-order goal of protecting one's own ship. In this task, however, CHEX rendered the operator even more vulnerable to attentional failures in change detection and increased perceived workload. Such support was only effective when participants performed a change detection task without concurrent subtasks. Results are interpreted in terms of the NSEEV model of attention behavior (Steelman, McCarley, & Wickens, Hum. Factors 53:142-153, 2011; J. Exp. Psychol. Appl. 19:403-419, 2013), and suggest that decision aids for use in multitasking contexts must be designed to fit within the available workload capacity of the user so that they may truly augment cognition.

Portals, blogs and co.: the role of the Internet as a medium of science communication.

PubMed

Minol, Klaus; Spelsberg, Gerd; Schulte, Elisabeth; Morris, Nicholas

2007-09-01

While the use of the Internet for the exchange of scientific data was characterised by exclusivity during its pioneer era, the active employment of the medium today, by a broad social spectrum of users in the exchange of information, for dialogue and in the accumulation of knowledge, displays an almost unbounded inclusion. Blo and online encyclopaedias based on the 'Wikipedia' model have contributed to the formation of a marketplace in which the free expression of opinions and the relaying of information occur. Counted among the ideas which have been popularised in the wake of this phenomenon, "lay journalism" and the "wisdom of the masses" are seen to be integral to the new 'web 2.0'. Consequently, the ever-increasing information disseminated in the web has been diluted in quality and authenticity, resulting in the presentation of new challenges to online science journalism. In reference to the public debate surrounding green gene technology, the communications platform bioSicherheit.de, which receives more than one million visitors per year, will be examined as an example of an agent that retrieves and mobilises information on biological safety research and that successfully has established itself as an intermediary between the scientific community and the broader public.

Looking at Earth observation impacts with fresh eyes: a Landsat example

NASA Astrophysics Data System (ADS)

Wu, Zhuoting; Snyder, Greg; Quirk, Bruce; Stensaas, Greg; Vadnais, Carolyn; Babcock, Michael; Dale, Erin; Doucette, Peter

2016-05-01

The U. S. Geological Survey (USGS) initiated the Requirements, Capabilities and Analysis for Earth Observations (RCA-EO) activity in the Land Remote Sensing (LRS) program to provide a structured approach to collect, store, maintain, and analyze user requirements and Earth observing system capabilities information. RCA-EO enables the collection of information on current key Earth observation products, services, and projects, and to evaluate them at different organizational levels within an agency, in terms of how reliant they are on Earth observation data from all sources, including spaceborne, airborne, and ground-based platforms. Within the USGS, RCA-EO has engaged over 500 subject matter experts in this assessment, and evaluated the impacts of more than 1000 different Earth observing data sources on 345 key USGS products and services. This paper summarizes Landsat impacts at various levels of the organizational structure of the USGS and highlights the feedback of the subject matter experts regarding Landsat data and Landsat-derived products. This feedback is expected to inform future Landsat mission decision making. The RCA-EO approach can be applied in a much broader scope to derive comprehensive knowledge of Earth observing system usage and impacts, to inform product and service development and remote sensing technology innovation beyond the USGS.

Demographic-Based Content Analysis of Web-Based Health-Related Social Media

PubMed Central

Shahbazi, Moloud; Wiley, Matthew T; Hristidis, Vagelis

2016-01-01

Background An increasing number of patients from diverse demographic groups share and search for health-related information on Web-based social media. However, little is known about the content of the posted information with respect to the users’ demographics. Objective The aims of this study were to analyze the content of Web-based health-related social media based on users’ demographics to identify which health topics are discussed in which social media by which demographic groups and to help guide educational and research activities. Methods We analyze 3 different types of health-related social media: (1) general Web-based social networks Twitter and Google+; (2) drug review websites; and (3) health Web forums, with a total of about 6 million users and 20 million posts. We analyzed the content of these posts based on the demographic group of their authors, in terms of sentiment and emotion, top distinctive terms, and top medical concepts. Results The results of this study are: (1) Pregnancy is the dominant topic for female users in drug review websites and health Web forums, whereas for male users, it is cardiac problems, HIV, and back pain, but this is not the case for Twitter; (2) younger users (0-17 years) mainly talk about attention-deficit hyperactivity disorder (ADHD) and depression-related drugs, users aged 35-44 years discuss about multiple sclerosis (MS) drugs, and middle-aged users (45-64 years) talk about alcohol and smoking; (3) users from the Northeast United States talk about physical disorders, whereas users from the West United States talk about mental disorders and addictive behaviors; (4) Users with higher writing level express less anger in their posts. Conclusion We studied the popular topics and the sentiment based on users' demographics in Web-based health-related social media. Our results provide valuable information, which can help create targeted and effective educational campaigns and guide experts to reach the right users on Web-based social chatter. PMID:27296242

Cracking induction in health libraries: is there a right way?

PubMed

Forgham-Healey, Nicola

2017-06-01

In most instances, inductions are the first time that users will be introduced to health library services. The time available in which to deliver library orientation sessions within a broader, Trust induction programme is often limited, and this can present challenges for health librarians. Inductions are a great marketing tool, and it is important that induction sessions make the right impact. Within a brief window of opportunity, the health librarian must impart key information to the inductees whilst ensuring the session is relevant and memorable. In this article, guest writer Nicola Healey, Library Manager of North Somerset Healthcare Library, discusses the range of approaches she and her colleagues have explored in delivering library inductions, explaining what worked, what did not and what areas still remain for development. H. S. © 2017 Health Libraries Group.

Overview of the Microgravity Science Glovebox (MSG)

NASA Technical Reports Server (NTRS)

Wright, Mary Etta

1999-01-01

MSG is a third generation glovebox for Microgravity Science investigations: SpaceLab Glovebox (GBX); Middeck/MIR Gloveboxes (M/MGBX); and GBX and M/MGBX developed by Bradford Engineering (NL). Previous flights have demonstrated utility of glovebox facilities: Contained environment enables broader range of science experiments; Affords better control of video and photographic imaging (a prime data source); Provides better environmental control than cabin atmosphere; and Useful for contingency operations. MSG developed in response to demands for increased work volume, increased capabilities and additional resources. MSG is multi-user facility to support a wide range of small science and technology investigations: Fluid physics; Combustion science; Material science; Biotechnology (cell culturing and protein crystal growth); Space processing; Fundamental physics; and Technology demonstrations. Topics included in this viewgraph are: MSG capabilities; MSG hardware items; MSG, GSE, and OSE items; MSG development approach; and Science utilization.

Preparing synthetic biology for the world

PubMed Central

Moe-Behrens, Gerd H. G.; Davis, Rene; Haynes, Karmella A.

2013-01-01

Synthetic Biology promises low-cost, exponentially scalable products and global health solutions in the form of self-replicating organisms, or “living devices.” As these promises are realized, proof-of-concept systems will gradually migrate from tightly regulated laboratory or industrial environments into private spaces as, for instance, probiotic health products, food, and even do-it-yourself bioengineered systems. What additional steps, if any, should be taken before releasing engineered self-replicating organisms into a broader user space? In this review, we explain how studies of genetically modified organisms lay groundwork for the future landscape of biosafety. Early in the design process, biological engineers are anticipating potential hazards and developing innovative tools to mitigate risk. Here, we survey lessons learned, ongoing efforts to engineer intrinsic biocontainment, and how different stakeholders in synthetic biology can act to accomplish best practices for biosafety. PMID:23355834

Putting Prevention in Their Pockets: Developing Mobile Phone-Based HIV Interventions for Black Men Who Have Sex with Men

PubMed Central

Pike, Emily C.; Fowler, Beth; LeGrand, Sara; Parsons, Jeffrey T.; Bull, Sheana S.; Wilson, Patrick A.; Wohl, David A.; Hightow-Weidman, Lisa B.

2013-01-01

Abstract Young black men who have sex with men (MSM) bear a disproportionate burden of HIV. Rapid expansion of mobile technologies, including smartphone applications (apps), provides a unique opportunity for outreach and tailored health messaging. We collected electronic daily journals and conducted surveys and focus groups with 22 black MSM (age 18–30) at three sites in North Carolina to inform the development of a mobile phone-based intervention. Qualitative data was analyzed thematically using NVivo. Half of the sample earned under $11,000 annually. All participants owned smartphones and had unlimited texting and many had unlimited data plans. Phones were integral to participants' lives and were a primary means of Internet access. Communication was primarily through text messaging and Internet (on-line chatting, social networking sites) rather than calls. Apps were used daily for entertainment, information, productivity, and social networking. Half of participants used their phones to find sex partners; over half used phones to find health information. For an HIV-related app, participants requested user-friendly content about test site locators, sexually transmitted diseases, symptom evaluation, drug and alcohol risk, safe sex, sexuality and relationships, gay-friendly health providers, and connection to other gay/HIV-positive men. For young black MSM in this qualitative study, mobile technologies were a widely used, acceptable means for HIV intervention. Future research is needed to measure patterns and preferences of mobile technology use among broader samples. PMID:23565925

ESIP's Emerging Provenance and Context Content Standard Use Cases: Developing Examples and Models for Data Stewardship

NASA Astrophysics Data System (ADS)

Ramdeen, S.; Hills, D. J.

2013-12-01

Earth science data collections range from individual researchers' private collections to large-scale data warehouses, from computer-generated data to field or lab based observations. These collections require stewardship. Fundamentally, stewardship ensures long term preservation and the provision of access to the user community. In particular, stewardship includes capturing appropriate metadata and documentation--and thus the context of the data's creation and any changes they underwent over time --to enable data reuse. But scientists and science data managers must translate these ideas into practice. How does one balance the needs of current and (projected) future stakeholders? In 2011, the Data Stewardship Committee (DSC) of the Federation of Earth Science Information Partners (ESIP) began developing the Provenance and Context Content Standard (PCCS). As an emerging standard, PCCS provides a framework for 'what' must be captured or preserved as opposed to describing only 'how' it should be done. Originally based on the experiences of NASA and NOAA researchers within ESIP, the standard currently provides data managers with content items aligned to eight key categories. While the categories and content items are based on data life cycles of remote sensing missions, they can be generalized to cover a broader set of activities, for example, preservation of physical objects. These categories will include the information needed to ensure the long-term understandability and usability of earth science data products. In addition to the PCCS, the DSC is developing a series of use cases based on the perspectives of the data archiver, data user, and the data consumer that will connect theory and practice. These cases will act as specifications for developing PCCS-based systems. They will also provide for examination of the categories and content items covered in the PCCS to determine if any additions are needed to cover the various use cases, and also provide rationale and indicate priorities for preservation. Though the use cases currently focus on two areas, 'creating' a data set and 'using' a data set, the use cases will eventually cover the full data lifecycle. Currently developing a template to be used in future use case creation, the DSC is also preparing and testing more use case scenarios. This presentation will introduce the ESIP use cases based on the PCCS. It will at once expand stakeholder participation and show the application of these materials beyond the ESIP community in which they were developed. More information about the ESIP use case activities can be found on the DSC wiki - http://wiki.esipfed.org/index.php/Preservation_Use_Case_Activity.

A method of designing smartphone interface based on the extended user's mental model

NASA Astrophysics Data System (ADS)

Zhao, Wei; Li, Fengmin; Bian, Jiali; Pan, Juchen; Song, Song

2017-01-01

The user's mental model is the core guiding theory of product design, especially practical products. The essence of practical product is a tool which is used by users to meet their needs. Then, the most important feature of a tool is usability. The design method based on the user's mental model provides a series of practical and feasible theoretical guidance for improving the usability of the product according to the user's awareness of things. In this paper, we propose a method of designing smartphone interface based on the extended user's mental model according to further research on user groups. This approach achieves personalized customization of smartphone application interface and enhance application using efficiency.

A workflow learning model to improve geovisual analytics utility

PubMed Central

Roth, Robert E; MacEachren, Alan M; McCabe, Craig A

2011-01-01

Introduction This paper describes the design and implementation of the G-EX Portal Learn Module, a web-based, geocollaborative application for organizing and distributing digital learning artifacts. G-EX falls into the broader context of geovisual analytics, a new research area with the goal of supporting visually-mediated reasoning about large, multivariate, spatiotemporal information. Because this information is unprecedented in amount and complexity, GIScientists are tasked with the development of new tools and techniques to make sense of it. Our research addresses the challenge of implementing these geovisual analytics tools and techniques in a useful manner. Objectives The objective of this paper is to develop and implement a method for improving the utility of geovisual analytics software. The success of software is measured by its usability (i.e., how easy the software is to use?) and utility (i.e., how useful the software is). The usability and utility of software can be improved by refining the software, increasing user knowledge about the software, or both. It is difficult to achieve transparent usability (i.e., software that is immediately usable without training) of geovisual analytics software because of the inherent complexity of the included tools and techniques. In these situations, improving user knowledge about the software through the provision of learning artifacts is as important, if not more so, than iterative refinement of the software itself. Therefore, our approach to improving utility is focused on educating the user. Methodology The research reported here was completed in two steps. First, we developed a model for learning about geovisual analytics software. Many existing digital learning models assist only with use of the software to complete a specific task and provide limited assistance with its actual application. To move beyond task-oriented learning about software use, we propose a process-oriented approach to learning based on the concept of scientific workflows. Second, we implemented an interface in the G-EX Portal Learn Module to demonstrate the workflow learning model. The workflow interface allows users to drag learning artifacts uploaded to the G-EX Portal onto a central whiteboard and then annotate the workflow using text and drawing tools. Once completed, users can visit the assembled workflow to get an idea of the kind, number, and scale of analysis steps, view individual learning artifacts associated with each node in the workflow, and ask questions about the overall workflow or individual learning artifacts through the associated forums. An example learning workflow in the domain of epidemiology is provided to demonstrate the effectiveness of the approach. Results/Conclusions In the context of geovisual analytics, GIScientists are not only responsible for developing software to facilitate visually-mediated reasoning about large and complex spatiotemporal information, but also for ensuring that this software works. The workflow learning model discussed in this paper and demonstrated in the G-EX Portal Learn Module is one approach to improving the utility of geovisual analytics software. While development of the G-EX Portal Learn Module is ongoing, we expect to release the G-EX Portal Learn Module by Summer 2009. PMID:21983545

A workflow learning model to improve geovisual analytics utility.

PubMed

Roth, Robert E; Maceachren, Alan M; McCabe, Craig A

2009-01-01

INTRODUCTION: This paper describes the design and implementation of the G-EX Portal Learn Module, a web-based, geocollaborative application for organizing and distributing digital learning artifacts. G-EX falls into the broader context of geovisual analytics, a new research area with the goal of supporting visually-mediated reasoning about large, multivariate, spatiotemporal information. Because this information is unprecedented in amount and complexity, GIScientists are tasked with the development of new tools and techniques to make sense of it. Our research addresses the challenge of implementing these geovisual analytics tools and techniques in a useful manner. OBJECTIVES: The objective of this paper is to develop and implement a method for improving the utility of geovisual analytics software. The success of software is measured by its usability (i.e., how easy the software is to use?) and utility (i.e., how useful the software is). The usability and utility of software can be improved by refining the software, increasing user knowledge about the software, or both. It is difficult to achieve transparent usability (i.e., software that is immediately usable without training) of geovisual analytics software because of the inherent complexity of the included tools and techniques. In these situations, improving user knowledge about the software through the provision of learning artifacts is as important, if not more so, than iterative refinement of the software itself. Therefore, our approach to improving utility is focused on educating the user. METHODOLOGY: The research reported here was completed in two steps. First, we developed a model for learning about geovisual analytics software. Many existing digital learning models assist only with use of the software to complete a specific task and provide limited assistance with its actual application. To move beyond task-oriented learning about software use, we propose a process-oriented approach to learning based on the concept of scientific workflows. Second, we implemented an interface in the G-EX Portal Learn Module to demonstrate the workflow learning model. The workflow interface allows users to drag learning artifacts uploaded to the G-EX Portal onto a central whiteboard and then annotate the workflow using text and drawing tools. Once completed, users can visit the assembled workflow to get an idea of the kind, number, and scale of analysis steps, view individual learning artifacts associated with each node in the workflow, and ask questions about the overall workflow or individual learning artifacts through the associated forums. An example learning workflow in the domain of epidemiology is provided to demonstrate the effectiveness of the approach. RESULTS/CONCLUSIONS: In the context of geovisual analytics, GIScientists are not only responsible for developing software to facilitate visually-mediated reasoning about large and complex spatiotemporal information, but also for ensuring that this software works. The workflow learning model discussed in this paper and demonstrated in the G-EX Portal Learn Module is one approach to improving the utility of geovisual analytics software. While development of the G-EX Portal Learn Module is ongoing, we expect to release the G-EX Portal Learn Module by Summer 2009.

Reinventing the International Space Station Payload Integration Processes and Capabilities

NASA Technical Reports Server (NTRS)

Jones, Rod; Price, Carmen; Copeland, Scott; Geiger, Wade; Geiger, Wade; Rice, Amanda; Lauchner, Adam

2011-01-01

The fundamental ISS payload integration philosophy, processes and capabilities were established in the context of how NASA science programs were conducted and executed in the early 1990 s. Today, with the designation of the United States (US) portion of ISS as a National Lab, the ISS payload customer base is growing to include other government agencies, private and commercial research. The fields of research are becoming more diverse expanding from the NASA centric physical, materials and human research sciences to test beds for exploration and technology demonstration, biology and biotechnology, and as an Earth and Space science platform. This new customer base has a broader more diverse set of expectations and requirements for payload design, verification, integration, test, training, and operations. One size fits all processes are not responsive to this broader customer base. To maintain an organization s effectiveness it must listen to its customers, understand their needs, learn from its mistakes, and foster an environment of continual process improvement. The ISS Payloads office is evolving to meet these new customer expectations.

(Un)organizing equal collaboration between users and professionals: on management of patient education in Norway.

PubMed

Stokken, Roar

2013-03-01

This is an article about how patient education is managed in Norway, but it also addresses a matter of broader relevance that of how an organization imbued with a request for rational choices is able to take on board a contradictory ideology. In Norway, patient education under the auspice of hospitals is to be conducted as an equal collaboration between users and professionals, posing challenges to the ethos of rationally justified choices within the hospital sector. This calls for an exploration of how the organization copes with the contradictory demands. A theoretical approach on the basis of theories from Scandinavian institutional theory and science and technology studies, informed by documents, interviews and experiences from national, regional and local levels in Norway. The field of patient education is divided into three decoupled domains: one at management level, one at the practical level, and in the middle a domain that acts as an interface between management and practice. This interface mediates the relationship between ideas and practice, without making overt the fact that ideas might not be possible to put into practice and that practice might not reflect ideas. The decoupling of practice and management allows patient education as equal collaboration between users and professionals to thrive as an idea, not subjugated by practical challenges. Thus, it can exist as a guiding star that both management and practitioners can attune to, but this situation might now be threatened by the demand for quality assurance in the field. © 2011 Blackwell Publishing Ltd.

(Un)organizing equal collaboration between users and professionals: on management of patient education in Norway

PubMed Central

Stokken, Roar

2011-01-01

Abstract Background  This is an article about how patient education is managed in Norway, but it also addresses a matter of broader relevance that of how an organization imbued with a request for rational choices is able to take on board a contradictory ideology. In Norway, patient education under the auspice of hospitals is to be conducted as an equal collaboration between users and professionals, posing challenges to the ethos of rationally justified choices within the hospital sector. This calls for an exploration of how the organization copes with the contradictory demands. Methods  A theoretical approach on the basis of theories from Scandinavian institutional theory and science and technology studies, informed by documents, interviews and experiences from national, regional and local levels in Norway. Discussion  The field of patient education is divided into three decoupled domains: one at management level, one at the practical level, and in the middle a domain that acts as an interface between management and practice. This interface mediates the relationship between ideas and practice, without making overt the fact that ideas might not be possible to put into practice and that practice might not reflect ideas. Conclusions  The decoupling of practice and management allows patient education as equal collaboration between users and professionals to thrive as an idea, not subjugated by practical challenges. Thus, it can exist as a guiding star that both management and practitioners can attune to, but this situation might now be threatened by the demand for quality assurance in the field. PMID:21624027

The Future of ECHO: Evaluating Open Source Possibilities

NASA Astrophysics Data System (ADS)

Pilone, D.; Gilman, J.; Baynes, K.; Mitchell, A. E.

2012-12-01

NASA's Earth Observing System ClearingHOuse (ECHO) is a format agnostic metadata repository supporting over 3000 collections and 100M science granules. ECHO exposes FTP and RESTful Data Ingest APIs in addition to both SOAP and RESTful search and order capabilities. Built on top of ECHO is a human facing search and order web application named Reverb. ECHO processes hundreds of orders, tens of thousands of searches, and 1-2M ingest actions each week. As ECHO's holdings, metadata format support, and visibility have increased, the ECHO team has received requests by non-NASA entities for copies of ECHO that can be run locally against their data holdings. ESDIS and the ECHO Team have begun investigations into various deployment and Open Sourcing models that can balance the real constraints faced by the ECHO project with the benefits of providing ECHO capabilities to a broader set of users and providers. This talk will discuss several release and Open Source models being investigated by the ECHO team along with the impacts those models are expected to have on the project. We discuss: - Addressing complex deployment or setup issues for potential users - Models of vetting code contributions - Balancing external (public) user requests versus our primary partners - Preparing project code for public release, including navigating licensing issues related to leveraged libraries - Dealing with non-free project dependencies such as commercial databases - Dealing with sensitive aspects of project code such as database passwords, authentication approaches, security through obscurity, etc. - Ongoing support for the released code including increased testing demands, bug fixes, security fixes, and new features.

Privacy-Preserving Authentication of Users with Smart Cards Using One-Time Credentials

NASA Astrophysics Data System (ADS)

Park, Jun-Cheol

User privacy preservation is critical to prevent many sophisticated attacks that are based on the user's server access patterns and ID-related information. We propose a password-based user authentication scheme that provides strong privacy protection using one-time credentials. It eliminates the possibility of tracing a user's authentication history and hides the user's ID and password even from servers. In addition, it is resistant against user impersonation even if both a server's verification database and a user's smart card storage are disclosed. We also provide a revocation scheme for a user to promptly invalidate the user's credentials on a server when the user's smart card is compromised. The schemes use lightweight operations only such as computing hashes and bitwise XORs.

Active Involvement of End Users When Developing Web-Based Mental Health Interventions.

PubMed

de Beurs, Derek; van Bruinessen, Inge; Noordman, Janneke; Friele, Roland; van Dulmen, Sandra

2017-01-01

Although many web-based mental health interventions are being released, the actual uptake by end users is limited. The marginal level of engagement of end users when developing these interventions is recognized as an important cause for uptake problems. In this paper, we offer our perceptive on how to improve user engagement. By doing so, we aim to stimulate a discourse on user involvement within the field of online mental health interventions. We shortly describe three different methods (the expert-driven method, intervention mapping, and scrum) that were currently used to develop web-based health interventions. We will focus to what extent the end user was involved in the developmental phase, and what the additional challenges were. In the final paragraph, lessons learned are summarized, and recommendations provided. Every method seems to have its trade-off: if end users are highly involved, availability of end users and means become problematic. If end users are less actively involved, the product may be less appropriate for the end user. Other challenges to consider are the funding of the more active role of technological companies, and the time it takes to process the results of shorter development cycles. Thinking about user-centered design and carefully planning, the involvement of end users should become standard in the field of web-based (mental) health. When deciding on the level of user involvement, one should balance the need for input from users with the availability of resources such as time and funding.

The promise and peril of intensive-site-based ecological research: insights from the Hubbard Brook ecosystem study

Treesearch

Timothy J. Fahey; Pamela H. Templer; Bruce T. Anderson; John J. Battles; John L. Campbell; Charles T. Driscoll; Anthony R. Fusco; Mark B. Green; Karim-Aly S. Kassam; Nicholas L. Rodenhouse; Lindsey Rustad; Paul G. Schaberg; Matthew A. Vadeboncoeur

2015-01-01

Ecological research is increasingly concentrated at particular locations or sites. This trend reflects a variety of advantages of intensive, site-based research, but also raises important questions about the nature of such spatially delimited research: how well does site based research represent broader areas, and does it constrain scientific discovery? We provide an...

The Validation of a Classroom Observation Instrument Based on the Construct of Teacher Adaptive Practice

ERIC Educational Resources Information Center

Loughland, Tony; Vlies, Penny

2016-01-01

Teacher adaptability is a key disposition for teachers that has been linked to outcomes of interests to schools. The aim of this study was to examine how the broader disposition of teacher adaptability might be observable as classroom-based adaptive practices using an argument-based approach to validation. The findings from the initial phase of…

Research-Based Knowledge: Researchers' Contribution to Evidence-Based Practice and Policy Making in Career Guidance

ERIC Educational Resources Information Center

Haug, Erik Hagaseth; Plant, Peter

2016-01-01

To present evidence for the outcomes of career guidance is increasingly seen as pivotal for a further professionalization of policy making and service provision. This paper puts an emphasis on researchers' contribution to evidence-based practice and policy making in career guidance. We argue for a broader and more pluralistic research strategy to…

Multidimensional display controller for displaying to a user an aspect of a multidimensional space visible from a base viewing location along a desired viewing orientation

DOEpatents

Davidson, George S.; Anderson, Thomas G.

2001-01-01

A display controller allows a user to control a base viewing location, a base viewing orientation, and a relative viewing orientation. The base viewing orientation and relative viewing orientation are combined to determine a desired viewing orientation. An aspect of a multidimensional space visible from the base viewing location along the desired viewing orientation is displayed to the user. The user can change the base viewing location, base viewing orientation, and relative viewing orientation by changing the location or other properties of input objects.

Library of Advanced Materials for Engineering (LAME) 4.44.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scherzinger, William M.; Lester, Brian T.

Accurate and efficient constitutive modeling remains a cornerstone issues for solid mechanics analysis. Over the years, the LAME advanced material model library has grown to address this challenge by implementing models capable of describing material systems spanning soft polymers to s ti ff ceramics including both isotropic and anisotropic responses. Inelastic behaviors including (visco) plasticity, damage, and fracture have all incorporated for use in various analyses. This multitude of options and flexibility, however, comes at the cost of many capabilities, features, and responses and the ensuing complexity in the resulting implementation. Therefore, to enhance confidence and enable the utilization ofmore » the LAME library in application, this effort seeks to document and verify the various models in the LAME library. Specifically, the broader strategy, organization, and interface of the library itself is first presented. The physical theory, numerical implementation, and user guide for a large set of models is then discussed. Importantly, a number of verification tests are performed with each model to not only have confidence in the model itself but also highlight some important response characteristics and features that may be of interest to end-users. Finally, in looking ahead to the future, approaches to add material models to this library and further expand the capabilities are presented.« less

Library of Advanced Materials for Engineering (LAME) 4.48.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scherzinger, William M.; Lester, Brian T.

Accurate and efficient constitutive modeling remains a cornerstone issues for solid mechanics analysis. Over the years, the LAME advanced material model library has grown to address this challenge by implement- ing models capable of describing material systems spanning soft polymers to stiff ceramics including both isotropic and anisotropic responses. Inelastic behaviors including (visco)plasticity, damage, and fracture have all incorporated for use in various analyses. This multitude of options and flexibility, however, comes at the cost of many capabilities, features, and responses and the ensuing complexity in the resulting imple- mentation. Therefore, to enhance confidence and enable the utilization of themore » LAME library in application, this effort seeks to document and verify the various models in the LAME library. Specifically, the broader strategy, organization, and interface of the library itself is first presented. The physical theory, numerical implementation, and user guide for a large set of models is then discussed. Importantly, a number of verifi- cation tests are performed with each model to not only have confidence in the model itself but also highlight some important response characteristics and features that may be of interest to end-users. Finally, in looking ahead to the future, approaches to add material models to this library and further expand the capabilities are presented.« less

Nuclear fuel performance: Trends, remedies and challenges

NASA Astrophysics Data System (ADS)

Rusch, C. A.

2008-12-01

It is unacceptable to have nuclear power plants unavailable or power restricted due to fuel reliability issues. 'Fuel reliability' has a much broader definition than just maintaining mechanical integrity and being leaker free - fuel must fully meet the specifications, impose no adverse impacts on plant operation and safety, and maintain quantifiable margins within design and operational envelopes. The fuel performance trends over the last decade are discussed and the significant contributors to reduced reliability experienced with commercial PWR and BWR designs are identified and discussed including grid-to-rod fretting and debris fretting in PWR designs and accelerated corrosion, debris fretting and pellet-cladding interaction in BWR designs. In many of these cases, the impacts have included not only fuel failures but also plant operating restrictions, forced shutdowns, and/or enhanced licensing authority oversight. Design and operational remedies are noted. The more demanding operating regimes and the constant quest to improve fuel performance require enhancements to current designs and/or new design features. Fuel users must continue to and enhance interaction with fuel suppliers in such areas as oversight of supplier design functions, lead test assembly irradiation programs and quality assurance oversight and surveillance. With the implementation of new designs and/or features, such fuel user initiatives can help to minimize the potential for performance problems.

An online database for IHN virus in Pacific Salmonid fish: MEAP-IHNV

USGS Publications Warehouse

Kurath, Gael

2012-01-01

The MEAP-IHNV database provides access to detailed data for anyone interested in IHNV molecular epidemiology, such as fish health professionals, fish culture facility managers, and academic researchers. The flexible search capabilities enable the user to generate various output formats, including tables and maps, which should assist users in developing and testing hypotheses about how IHNV moves across landscapes and changes over time. The MEAP-IHNV database is available online at http://gis.nacse.org/ihnv/ (fig. 1). The database contains records that provide background information and genetic sequencing data for more than 1,000 individual field isolates of the fish virus Infectious hematopoietic necrosis virus (IHNV), and is updated approximately annually. It focuses on IHNV isolates collected throughout western North America from 1966 to the present. The database also includes a small number of IHNV isolates from Eastern Russia. By engaging the expertise of the broader community of colleagues interested in IHNV, our goal is to enhance the overall understanding of IHNV epidemiology, including defining sources of disease outbreaks and viral emergence events, identifying virus traffic patterns and potential reservoirs, and understanding how human management of salmonid fish culture affects disease. Ultimately, this knowledge can be used to develop new strategies to reduce the effect of IHN disease in cultured and wild fish.

Examining Tensions That Affect the Evaluation of Technology in Health Care: Considerations for System Decision Makers From the Perspective of Industry and Evaluators.

PubMed

Desveaux, Laura; Shaw, James; Wallace, Ross; Bhattacharyya, Onil; Bhatia, R Sacha; Jamieson, Trevor

2017-12-08

Virtual technologies have the potential to mitigate a range of challenges for health care systems. Despite the widespread use of mobile devices in everyday life, they currently have a limited role in health service delivery and clinical care. Efforts to integrate the fast-paced consumer technology market with health care delivery exposes tensions among patients, providers, vendors, evaluators, and system decision makers. This paper explores the key tensions between the high bar for evidence prior to market approval that guides health care regulatory decisions and the "fail fast" reality of the technology industry. We examine three core tensions: balancing user needs versus system needs, rigor versus responsiveness, and the role of pre- versus postmarket evidence generation. We use these to elaborate on the structure and appropriateness of evaluation mechanisms for virtual care solutions. Virtual technologies provide a foundation for personalized, patient-centered medicine on the user side, coupled with a broader understanding of impact on the system side. However, mechanisms for stakeholder discussion are needed to clarify the nature of the health technology marketplace and the drivers of evaluation priorities. ©Laura Desveaux, James Shaw, Ross Wallace, Onil Bhattacharyya, R Sacha Bhatia, Trevor Jamieson. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 08.12.2017.

FADTTSter: accelerating hypothesis testing with functional analysis of diffusion tensor tract statistics

NASA Astrophysics Data System (ADS)

Noel, Jean; Prieto, Juan C.; Styner, Martin

2017-03-01

Functional Analysis of Diffusion Tensor Tract Statistics (FADTTS) is a toolbox for analysis of white matter (WM) fiber tracts. It allows associating diffusion properties along major WM bundles with a set of covariates of interest, such as age, diagnostic status and gender, and the structure of the variability of these WM tract properties. However, to use this toolbox, a user must have an intermediate knowledge in scripting languages (MATLAB). FADTTSter was created to overcome this issue and make the statistical analysis accessible to any non-technical researcher. FADTTSter is actively being used by researchers at the University of North Carolina. FADTTSter guides non-technical users through a series of steps including quality control of subjects and fibers in order to setup the necessary parameters to run FADTTS. Additionally, FADTTSter implements interactive charts for FADTTS' outputs. This interactive chart enhances the researcher experience and facilitates the analysis of the results. FADTTSter's motivation is to improve usability and provide a new analysis tool to the community that complements FADTTS. Ultimately, by enabling FADTTS to a broader audience, FADTTSter seeks to accelerate hypothesis testing in neuroimaging studies involving heterogeneous clinical data and diffusion tensor imaging. This work is submitted to the Biomedical Applications in Molecular, Structural, and Functional Imaging conference. The source code of this application is available in NITRC.

Centralized Research Recruitment—Evolving a Local Clinical Research Recruitment Web Application to Better Meet User Needs

PubMed Central

Dwyer‐White, Molly; Doshi, Aalap; Hill, Mary; Pienta, Kenneth J.

2011-01-01

Abstract  Recruiting volunteers into clinical research remains a significant challenge for many clinical research study teams, thus the Michigan Institute for Clinical and Health Research (MICHR) at the University of Michigan developed UMClinicalStudies (http://www.UMClinicalStudies.org)—a Web application that links the community to a single gateway for clinical research. UMClinicalStudies (formerly named “Engage”) is an integral piece of MICHR’s efforts to increase clinical research participation in order to advance medical discoveries. Despite the initial success of the application, barriers to research participation remain, including the applications accessibility for potential research volunteers and study team members. In response, new initiatives were instigated to identify user needs, in order to broaden the ability to simultaneously assist researchers in recruitment activities, while also aiding potential volunteers in the exploration of and participation in clinical research opportunities. To do this, improvements to the interface and functionality were identified and implemented for both the public and the research audiences through extensive system analysis, and through the application of human computer interactivity processes, resulting in significant improvements in usability and ultimately research volunteerism, indicating that utilizing such technology is pivotal in reaching broader audiences for clinical trial participation. Clin Trans Sci 2011; Volume 4: 363–368 PMID:22029810

Argonne Leadership Computing Facility 2011 annual report : Shaping future supercomputing.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Papka, M.; Messina, P.; Coffey, R.

The ALCF's Early Science Program aims to prepare key applications for the architecture and scale of Mira and to solidify libraries and infrastructure that will pave the way for other future production applications. Two billion core-hours have been allocated to 16 Early Science projects on Mira. The projects, in addition to promising delivery of exciting new science, are all based on state-of-the-art, petascale, parallel applications. The project teams, in collaboration with ALCF staff and IBM, have undertaken intensive efforts to adapt their software to take advantage of Mira's Blue Gene/Q architecture, which, in a number of ways, is a precursormore » to future high-performance-computing architecture. The Argonne Leadership Computing Facility (ALCF) enables transformative science that solves some of the most difficult challenges in biology, chemistry, energy, climate, materials, physics, and other scientific realms. Users partnering with ALCF staff have reached research milestones previously unattainable, due to the ALCF's world-class supercomputing resources and expertise in computation science. In 2011, the ALCF's commitment to providing outstanding science and leadership-class resources was honored with several prestigious awards. Research on multiscale brain blood flow simulations was named a Gordon Bell Prize finalist. Intrepid, the ALCF's BG/P system, ranked No. 1 on the Graph 500 list for the second consecutive year. The next-generation BG/Q prototype again topped the Green500 list. Skilled experts at the ALCF enable researchers to conduct breakthrough science on the Blue Gene system in key ways. The Catalyst Team matches project PIs with experienced computational scientists to maximize and accelerate research in their specific scientific domains. The Performance Engineering Team facilitates the effective use of applications on the Blue Gene system by assessing and improving the algorithms used by applications and the techniques used to implement those algorithms. The Data Analytics and Visualization Team lends expertise in tools and methods for high-performance, post-processing of large datasets, interactive data exploration, batch visualization, and production visualization. The Operations Team ensures that system hardware and software work reliably and optimally; system tools are matched to the unique system architectures and scale of ALCF resources; the entire system software stack works smoothly together; and I/O performance issues, bug fixes, and requests for system software are addressed. The User Services and Outreach Team offers frontline services and support to existing and potential ALCF users. The team also provides marketing and outreach to users, DOE, and the broader community.« less

Federating Metadata Catalogs

NASA Astrophysics Data System (ADS)

Baru, C.; Lin, K.

2009-04-01

The Geosciences Network project (www.geongrid.org) has been developing cyberinfrastructure for data sharing in the Earth Science community based on a service-oriented architecture. The project defines a standard "software stack", which includes a standardized set of software modules and corresponding service interfaces. The system employs Grid certificates for distributed user authentication. The GEON Portal provides online access to these services via a set of portlets. This service-oriented approach has enabled the GEON network to easily expand to new sites and deploy the same infrastructure in new projects. To facilitate interoperation with other distributed geoinformatics environments, service standards are being defined and implemented for catalog services and federated search across distributed catalogs. The need arises because there may be multiple metadata catalogs in a distributed system, for example, for each institution, agency, geographic region, and/or country. Ideally, a geoinformatics user should be able to search across all such catalogs by making a single search request. In this paper, we describe our implementation for such a search capability across federated metadata catalogs in the GEON service-oriented architecture. The GEON catalog can be searched using spatial, temporal, and other metadata-based search criteria. The search can be invoked as a Web service and, thus, can be imbedded in any software application. The need for federated catalogs in GEON arises because, (i) GEON collaborators at the University of Hyderabad, India have deployed their own catalog, as part of the iGEON-India effort, to register information about local resources for broader access across the network, (ii) GEON collaborators in the GEO Grid (Global Earth Observations Grid) project at AIST, Japan have implemented a catalog for their ASTER data products, and (iii) we have recently deployed a search service to access all data products from the EarthScope project in the US (http://es-portal.geongrid.org), which are distributed across data archives at IRIS in Seattle, Washington, UNAVCO in Boulder, Colorado, and at the ICDP archives in GFZ, Potsdam, Germany. This service implements a "virtual" catalog--the actual/"physical" catalogs and data are stored at each of the remote locations. A federated search across all these catalogs would enable GEON users to discover data across all of these environments with a single search request. Our objective is to implement this search service via the OGC Catalog Services for the Web (CS-W) standard by providing appropriate CSW "wrappers" for each metadata catalog, as necessary. This paper will discuss technical issues in designing and deploying such a multi-catalog search service in GEON and describe an initial prototype of the federated search capability.

User-Friendly Data-Sharing Practices for Fostering Collaboration within a Research Network: Roles of a Vanguard Center for a Community-Based Study

PubMed Central

Lee, Jae Eun; Sung, Jung Hye; Barnett, M. Edwina; Norris, Keith

2015-01-01

Although various attempts have been made to build collaborative cultures for data sharing, their effectiveness is still questionable. The Jackson Heart Study (JHS) Vanguard Center (JHSVC) at the NIH-funded Research Centers in Minority Institutions (RCMI) Translational Research Network (RTRN) Data Coordinating Center (DCC) may be a new concept in that the data are being shared with a research network where a plethora of scientists/researchers are working together to achieve their common goal. This study describes the current practices to share the JHS data through the mechanism of JHSVC. The JHS is the largest single-site cohort study to prospectively investigate the determinants of cardiovascular disease among African-Americans. It has adopted a formal screened access method through a formalized JHSVC mechanism, in which only a qualified scientist(s) can access the data. The role of the DCC was to help RTRN researchers explore hypothesis-driven ideas to enhance the output and impact of JHS data through customized services, such as feasibility tests, data querying, manuscript proposal development and data analyses for publication. DCC has implemented these various programs to facilitate data utility. A total of 300 investigators attended workshops and/or received training booklets. DCC provided two online and five onsite workshops and developed/distributed more than 250 copies of the booklet to help potential data users understand the structure of and access to the data. Information on data use was also provided through the RTRN website. The DCC efforts led to the production of five active manuscript proposals, seven completed publications, 11 presentations and four NIH grant proposals. These outcomes resulted from activities during the first four years; over the last couple of years, there were few new requests. Our study suggested that DCC-customized services enhanced the accessibility of JHS data and their utility by RTRN researchers and helped to achieve the principal goal of JHSVC of scientific productivity. In order to achieve long-term success, the following, but not limited to these, should be addressed in the current data sharing practices: preparation of new promotional strategies in response to changes in technology and users’ needs, collaboration with the Network statisticians, harmonization of the JHS data with the other local-based heart datasets to meet the needs of the potential users from the broader geographical areas, adoption of the RTRN comprehensive data-sharing policy to broaden the variety of research topics and implementation of an ongoing monitoring program to evaluate its success. PMID:26703645

Status of High Power Technology for Educational Satellites.

ERIC Educational Resources Information Center

Kuhns, Perry W.

The increasing desire to answer the educational needs of all segments of the population will necessitate a broader based communications system such as one based on satellites. The new system will require additional terminals, more interconnections, and more frequencies than are presently in use. To accomplish these goals, we need to use higher…

Developing Online Learning Resources: Big Data, Social Networks, and Cloud Computing to Support Pervasive Knowledge

ERIC Educational Resources Information Center

Anshari, Muhammad; Alas, Yabit; Guan, Lim Sei

2016-01-01

Utilizing online learning resources (OLR) from multi channels in learning activities promise extended benefits from traditional based learning-centred to a collaborative based learning-centred that emphasises pervasive learning anywhere and anytime. While compiling big data, cloud computing, and semantic web into OLR offer a broader spectrum of…

New Comparative Measures of Income, Material Deprivation, and Well-Being

ERIC Educational Resources Information Center

Smeeding, Timothy M.

2009-01-01

Most societies, rich and poor, seek to measure progress in reducing poverty and need, as indicated by material deprivation or social exclusion. The yardsticks used to assess progress and policy impact mainly include income-based poverty, but broader measures of poverty based on consumption, wealth, and material deprivation are also now coming into…

Cognitive Process as a Basis for Intelligent Retrieval Systems Design.

ERIC Educational Resources Information Center

Chen, Hsinchun; Dhar, Vasant

1991-01-01

Two studies of the cognitive processes involved in online document-based information retrieval were conducted. These studies led to the development of five computational models of online document retrieval which were incorporated into the design of an "intelligent" document-based retrieval system. Both the system and the broader implications of…

State Initiatives on Industry-Based Skill Standards and Credentials.

ERIC Educational Resources Information Center

Ganzglass, Evelyn; Simon, Martin

A study examined state initiatives for industry-based skill standards and credentials. Officials in 19 states were interviewed, case studies of programs in 3 states (Georgia, Pennsylvania, and Texas) were conducted, and focus group discussions were held with 25 individuals. State skill standards were generally found to be tied to broader efforts…

School-Based Management: The Changing Locus of Control in American Public Education.

ERIC Educational Resources Information Center

Drury, Darrel; Levin, Douglas

School-based management is a reinvention and countermovement to a broader historical trend to centralize and standardize American education. The present study represents one component of the Organisation for Economic Cooperation and Development's project to investigate how schools in 12 member nations can most effectively respond to recent…

Mobile Health Physical Activity Intervention Preferences in Cancer Survivors: A Qualitative Study

PubMed Central

Robertson, Michael C; Tsai, Edward; Lyons, Elizabeth J; Srinivasan, Sanjana; Swartz, Maria C; Baum, Miranda L

2017-01-01

Background Cancer survivors are at an elevated risk for several negative health outcomes, but physical activity (PA) can decrease those risks. Unfortunately, adherence to PA recommendations among survivors is low. Fitness mobile apps have been shown to facilitate the adoption of PA in the general population, but there are limited apps specifically designed for cancer survivors. This population has unique needs and barriers to PA, and most existing PA apps do not address these issues. Moreover, incorporating user preferences has been identified as an important priority for technology-based PA interventions, but at present there is limited literature that serves to establish these preferences in cancer survivors. This is especially problematic given the high cost of app development and because the majority of downloaded apps fail to engage users over the long term. Objective The aim of this study was to take a qualitative approach to provide practical insight regarding this population’s preferences for the features and messages of an app to increase PA. Methods A total of 35 cancer survivors each attended 2 focus groups; a moderator presented slide shows on potential app features and messages and asked open-ended questions to elicit participant preferences. All sessions were audio recorded and transcribed verbatim. Three reviewers independently conducted thematic content analysis on all transcripts, then organized and consolidated findings to identify salient themes. Results Participants (mean age 63.7, SD 10.8, years) were mostly female (24/35, 69%) and mostly white (25/35, 71%). Participants generally had access to technology and were receptive to engaging with an app to increase PA. Themes identified included preferences for (1) a casual, concise, and positive tone, (2) tools for personal goal attainment, (3) a prescription for PA, and (4) an experience that is tailored to the user. Participants reported wanting extensive background data collection with low data entry burden and to have a trustworthy source translate their personal data into individualized PA recommendations. They expressed a desire for app functions that could facilitate goal achievement and articulated a preference for a more private social experience. Finally, results indicated that PA goals might be best established in the context of personally held priorities and values. Conclusions Many of the desired features identified are compatible with both empirically supported methods of behavior change and the relative strengths of an app as a delivery vehicle for behavioral intervention. Participating cancer survivors’ preferences contrasted with many current standard practices for mobile app development, including value-based rather than numeric goals, private socialization in small groups rather than sharing with broader social networks, and interpretation of PA data rather than merely providing numerical data. Taken together, these insights may help increase the acceptability of theory-based mHealth PA interventions in cancer survivors. PMID:28119278

SoRS: Social recommendation using global rating reputation and local rating similarity

NASA Astrophysics Data System (ADS)

Qian, Fulan; Zhao, Shu; Tang, Jie; Zhang, Yanping

2016-11-01

Recommendation is an important and also challenging problem in online social networks. It needs to consider not only users' personalized interests, but also social relations between users. Indeed, in practice, users are often inclined to accept recommendations from friends or opinion leaders (users with high reputations). In this paper, we present a novel recommendation framework, social recommendation using global rating reputation and local rating similarity, which combine user reputation and social similarity based on ratings. User reputation can be obtained by iteratively calculating the correlation of historical ratings of user and intrinsic qualities of items. We view the user reputation as the user's global influence and the similarity based on rating of social relation as the user's local influence, introduce it in the basic social recommender model. Thus users with high reputation have a strong influence on the others, and on the other hand, the effect of a user with low reputation has been weakened. The recommendation accuracy of proposed framework can be improved by effectively removing nature noise because of less rigorous user ratings and strengthening the effect of user influence with high reputation. We also improve the similarity based on ratings by avoiding the high similarity with the less common ratings between friends. We evaluate our approach on three datasets including Movielens, Epinions and Douban. Empirical results demonstrate that proposed framework achieves significant improvements on recommendation accuracy. User reputation and local similarity which are both based on ratings have a lot of helpful in improvement of prediction accuracy. The reputation also can help to improve the recommendation precision with the small training sets.

47 CFR 64.613 - Numbering directory for internet-based TRS users.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Numbering directory for internet-based TRS... for internet-based TRS users. (a) TRS Numbering Directory. (1) The TRS Numbering Directory shall contain records mapping the NANP telephone number of each Registered Internet-based TRS User to a unique...

Role-Based And Adaptive User Interface Designs In A Teledermatology Consult System: A Way To Secure And A Way To Enhance

PubMed Central

Lin, Yi-Jung; Speedie, Stuart

2003-01-01

User interface design is one of the most important parts of developing applications. Nowadays, a quality user interface must not only accommodate interaction between machines and users, but also needs to recognize the differences and provide functionalities for users from role-to-role or even individual-to-individual. With the web-based application of our Teledermatology consult system, the development environment provides us highly useful opportunities to create dynamic user interfaces, which lets us to gain greater access control and has the potential to increase efficiency of the system. We will describe the two models of user interfaces in our system: Role-based and Adaptive. PMID:14728419

Hospital-Based Acute Care After Total Hip and Knee Arthroplasty: Implications for Quality Measurement.

PubMed

Trimba, Roman; Laughlin, Richard T; Krishnamurthy, Anil; Ross, Joseph S; Fox, Justin P

2016-03-01

Although hospital readmissions are being adopted as a quality measure after total hip or knee arthroplasty, they may fail accurately capture the patient's postdischarge experience. We studied 272,853 discharges from 517 hospitals to determine hospital emergency department (ED) visit and readmission rates. The hospital-level, 30-day, risk-standardized ED visit (median = 5.6% [2.4%-13.7%]) and hospital readmission (5.0% [2.6%-9.2%]) rates were similar and varied widely. A hospital's risk-standardized ED visit rate did not correlate with its readmission rate (r = -0.03, P = .50). If ED visits were included in a broader "readmission" measure, 246 (47.6%) hospitals would change perceived performance groups. Including ED visits in a broader, hospital-based, acute care measure may be warranted to better describe postdischarge health care utilization. Copyright © 2016 Elsevier Inc. All rights reserved.

Components for Maintaining and Publishing Earth Science Vocabularies

NASA Astrophysics Data System (ADS)

Cox, S. J. D.; Yu, J.

2014-12-01

Shared vocabularies are an important aid to geoscience data interoperability. Many organizations maintain useful vocabularies, with Geologic Surveys having a particularly long history of vocabulary and lexicon development. However, the mode of publication is heterogeneous, ranging from PDFs and HTML web pages, spreadsheets and CSV, through various user-interfaces and APIs. Update and maintenance ranges from tightly-governed and externally opaque, through various community processes, all the way to crowd-sourcing ('folksonomies'). A general expectation, however, is for greater harmonization and vocabulary re-use. In order to be successful this requires (a) standardized content formalization and APIs (b) transparent content maintenance and versioning. We have been trialling a combination of software dealing with registration, search and linking. SKOS is designed for formalizing multi-lingual, hierarchical vocabularies, and has been widely adopted in earth and environmental sciences. SKOS is an RDF vocabulary, for which SPARQL is the standard low-level API. However, for interoperability between SKOS vocabulary sources, a SKOS-based API (i.e. based on the SKOS predicates prefLabel, broader, narrower, etc) is required. We have developed SISSvoc for this purpose, and used it to deploy a number of vocabularies on behalf of the IUGS, ICS, NERC, OGC, the Australian Government, and CSIRO projects. SISSvoc Search provides simple search UI on top of one or more SISSvoc sources. Content maintenance is composed of many elements, including content-formalization, definition-update, and mappings to related vocabularies. Typically there is a degree of expert judgement required. In order to provide confidence in users, two requirements are paramount: (i) once published, a URI that denotes a vocabulary item must remain dereferenceable; (ii) the history and status of the content denoted by a URI must be available. These requirements match the standard 'registration' paradigm which is implemented in the Linked Data Registry, which is currently used by WMO and the UK Environment Agency for publication of vocabularies. Together, these components provide a powerful and flexible system for providing earth science vocabularies for the community, consistent with semantic web and linked-data principles.

Plant Distribution Data Show Broader Climatic Limits than Expert-Based Climatic Tolerance Estimates

PubMed Central

Curtis, Caroline A.; Bradley, Bethany A.

2016-01-01

Background Although increasingly sophisticated environmental measures are being applied to species distributions models, the focus remains on using climatic data to provide estimates of habitat suitability. Climatic tolerance estimates based on expert knowledge are available for a wide range of plants via the USDA PLANTS database. We aim to test how climatic tolerance inferred from plant distribution records relates to tolerance estimated by experts. Further, we use this information to identify circumstances when species distributions are more likely to approximate climatic tolerance. Methods We compiled expert knowledge estimates of minimum and maximum precipitation and minimum temperature tolerance for over 1800 conservation plant species from the ‘plant characteristics’ information in the USDA PLANTS database. We derived climatic tolerance from distribution data downloaded from the Global Biodiversity and Information Facility (GBIF) and corresponding climate from WorldClim. We compared expert-derived climatic tolerance to empirical estimates to find the difference between their inferred climate niches (ΔCN), and tested whether ΔCN was influenced by growth form or range size. Results Climate niches calculated from distribution data were significantly broader than expert-based tolerance estimates (Mann-Whitney p values << 0.001). The average plant could tolerate 24 mm lower minimum precipitation, 14 mm higher maximum precipitation, and 7° C lower minimum temperatures based on distribution data relative to expert-based tolerance estimates. Species with larger ranges had greater ΔCN for minimum precipitation and minimum temperature. For maximum precipitation and minimum temperature, forbs and grasses tended to have larger ΔCN while grasses and trees had larger ΔCN for minimum precipitation. Conclusion Our results show that distribution data are consistently broader than USDA PLANTS experts’ knowledge and likely provide more robust estimates of climatic tolerance, especially for widespread forbs and grasses. These findings suggest that widely available expert-based climatic tolerance estimates underrepresent species’ fundamental niche and likely fail to capture the realized niche. PMID:27870859

Serving women who use drugs in Delhi, India: challenges and achievements.

PubMed

Sarin, Enisha; Selhore, Elizabeth

2008-04-01

Sharan and Sahara, two NGOs working in Delhi, India, in the field of drug use and HIV/AIDS, present some key challenges as well as lessons learned in working with women who use drugs. Although there is no official estimate of the number of women drug users in Delhi, outreach reports indicate a hidden population of women users in the slums and streets of Delhi. A rapid situation assessment (RSA) conducted in 2000 by Sharan found urban poor women using drugs in Delhi with multiple issues related to their health, livelihoods, and relationships that put them at risk of severe health problems including HIV. The findings of the RSA led to intensified and focused intervention for women users by Sahara and Sharan. This is a discussion on a gender specific intervention ongoing in Delhi by delineating the particular achievements and challenges faced in working with women who use drugs. The article also looks at broader challenges that are outside the scope of this particular intervention but which nevertheless affect the well being of women who use drugs. Out of the 3700 women who have been rehabilitated in Sahara, 40% have found employment, while another 10% have been reintegrated into their families. There is however, an overdependence on its services that impedes their successful transition to mainstream life. One of the biggest limitations in the design of drug treatment interventions in Delhi is that there is a lack of diverse treatment options for women users. Only indoor detoxification and rehabilitation facilities are available for women; even these not offering a quality of care commensurate with the needs of the women. Lack of mental health care in drug treatment centres is felt to be a huge gap in services. Finally, NGOs like Sharan and Sahara are obliged to take up the entire continuum of care services which limits their ability to provide optimal care and services to women who use drugs. Lack of funds and lack of understanding among funding agencies about issues of women users are additional limitations in service provision. A multi-sectoral response is a viable response to the multi-dimensional problem of women drug use.

Building a Generic Virtual Research Environment Framework for Multiple Earth and Space Science Domains and a Diversity of Users.

NASA Astrophysics Data System (ADS)

Wyborn, L. A.; Fraser, R.; Evans, B. J. K.; Friedrich, C.; Klump, J. F.; Lescinsky, D. T.

2017-12-01

Virtual Research Environments (VREs) are now part of academic infrastructures. Online research workflows can be orchestrated whereby data can be accessed from multiple external repositories with processing taking place on public or private clouds, and centralised supercomputers using a mixture of user codes, and well-used community software and libraries. VREs enable distributed members of research teams to actively work together to share data, models, tools, software, workflows, best practices, infrastructures, etc. These environments and their components are increasingly able to support the needs of undergraduate teaching. External to the research sector, they can also be reused by citizen scientists, and be repurposed for industry users to help accelerate the diffusion and hence enable the translation of research innovations. The Virtual Geophysics Laboratory (VGL) in Australia was started in 2012, built using a collaboration between CSIRO, the National Computational Infrastructure (NCI) and Geoscience Australia, with support funding from the Australian Government Department of Education. VGL comprises three main modules that provide an interface to enable users to first select their required data; to choose a tool to process that data; and then access compute infrastructure for execution. VGL was initially built to enable a specific set of researchers in government agencies access to specific data sets and a limited number of tools. Over the years it has evolved into a multi-purpose Earth science platform with access to an increased variety of data (e.g., Natural Hazards, Geochemistry), a broader range of software packages, and an increasing diversity of compute infrastructures. This expansion has been possible because of the approach to loosely couple data, tools and compute resources via interfaces that are built on international standards and accessed as network-enabled services wherever possible. Built originally for researchers that were not fussy about general usability, increasing emphasis on User Interfaces (UIs) and stability will lead to increased uptake in the education and industry sectors. Simultaneously, improvements are being added to facilitate access to data and tools by experienced researchers who want direct access to both data and flexible workflows.

Net-Centric Warfare 2.0: Cloud Computing and the New Age of War

DTIC Science & Technology

2009-02-01

Ellyssa Kroski, author of The Hive Mind: Folksonomies and User-based Tagging, writes: “With the advent of social software and Web 2.0, we usher in a new... Folksonomies and User-Based Tagging, (2007), http://infotangle.blogsome. com/2005/12/07/the-hive-mind- folksonomies -and-user-based-tagging/. 45 Office...www.govexec.com/dailyfed/1007/101007cdam1.htm (accessed February 4, 2009). Kroski, Ellyssa. "The Hive Mind: Folksonomies and User-Based Tagging

Personalized recommendation via unbalance full-connectivity inference

NASA Astrophysics Data System (ADS)

Ma, Wenping; Ren, Chen; Wu, Yue; Wang, Shanfeng; Feng, Xiang

2017-10-01

Recommender systems play an important role to help us to find useful information. They are widely used by most e-commerce web sites to push the potential items to individual user according to purchase history. Network-based recommendation algorithms are popular and effective in recommendation, which use two types of elements to represent users and items respectively. In this paper, based on consistence-based inference (CBI) algorithm, we propose a novel network-based algorithm, in which users and items are recognized with no difference. The proposed algorithm also uses information diffusion to find the relationship between users and items. Different from traditional network-based recommendation algorithms, information diffusion initializes from users and items, respectively. Experiments show that the proposed algorithm is effective compared with traditional network-based recommendation algorithms.

Mileage-based user fees : defining a path toward implementation phase 2, an assessment of technology issues : final report

DOT National Transportation Integrated Search

2009-10-01

This report reviews technology options for a mileage-based user fee system in the state of Texas. The report was : compiled based on input from a diverse range of sources, including a literature review of existing mileage-based : user fee technical w...

Catalog Federation and Interoperability for Geoinformatics

NASA Astrophysics Data System (ADS)

Memon, A.; Lin, K.; Baru, C.

2008-12-01

With the increasing proliferation of online resources in the geosciences, including data, tools, and software services, there is also a proliferation of catalogs containing metadata that describe these resources. To realize the vision articulated in the NSF Workshop on Building a National Geoinformatics System, March 2007-where a user can sit at a terminal and easily search, discover, integrate and use distributed geoscience resources-it will be essential that a search request be able to traverse these multiple metadata catalogs. In this paper, we describe our effort at prototyping catalog interoperability across multiple metadata catalogs. An example of a metadata catalog is the one employed in the GEON Project (www.geongrid.org). The central GEON catalog can be searched using spatial, temporal, and other metadata-based search criteria. The search can be invoked as a Web service and, therefore, can be imbedded in any software application. There has been a requirement from some of the GEON collaborators (for example, at the University of Hyderabad, India and the Navajo Technical College, New Mexico) to deploy their own catalogs, to store information about their resources locally, while they publish some of this information for broader access and use. Thus, a search must now be able to span multiple, independent GEON catalogs. Next, some of our collaborators-e.g. GEO Grid (Global Earth Observations Grid) in Japan-are implementing the Catalog Services for the Web (CS-W) standard for their catalog, thereby requiring the search to span across catalogs implemented using the CS-W standard as well. Finally, we have recently deployed a search service to access all EarthScope data products, which are distributed across organizations in Seattle, WA (IRIS), Boulder, CO (UNAVCO), and Potsdam, Germany (ICDP/GFZ). This service essentially implements a virtual catalog (the actual catalogs and data are stored at the remote locations). So, there is the need to incorporate such 3rd party searches within a broader search function, such as GEONsearch in the GEON Portal. We will discuss technical issues involved in designing and deploying such a multi-catalog search service in GEON.

Interface Prostheses With Classifier-Feedback-Based User Training.

PubMed

Fang, Yinfeng; Zhou, Dalin; Li, Kairu; Liu, Honghai

2017-11-01

It is evident that user training significantly affects performance of pattern-recognition-based myoelectric prosthetic device control. Despite plausible classification accuracy on offline datasets, online accuracy usually suffers from the changes in physiological conditions and electrode displacement. The user ability in generating consistent electromyographic (EMG) patterns can be enhanced via proper user training strategies in order to improve online performance. This study proposes a clustering-feedback strategy that provides real-time feedback to users by means of a visualized online EMG signal input as well as the centroids of the training samples, whose dimensionality is reduced to minimal number by dimension reduction. Clustering feedback provides a criterion that guides users to adjust motion gestures and muscle contraction forces intentionally. The experiment results have demonstrated that hand motion recognition accuracy increases steadily along the progress of the clustering-feedback-based user training, while conventional classifier-feedback methods, i.e., label feedback, hardly achieve any improvement. The result concludes that the use of proper classifier feedback can accelerate the process of user training, and implies prosperous future for the amputees with limited or no experience in pattern-recognition-based prosthetic device manipulation.It is evident that user training significantly affects performance of pattern-recognition-based myoelectric prosthetic device control. Despite plausible classification accuracy on offline datasets, online accuracy usually suffers from the changes in physiological conditions and electrode displacement. The user ability in generating consistent electromyographic (EMG) patterns can be enhanced via proper user training strategies in order to improve online performance. This study proposes a clustering-feedback strategy that provides real-time feedback to users by means of a visualized online EMG signal input as well as the centroids of the training samples, whose dimensionality is reduced to minimal number by dimension reduction. Clustering feedback provides a criterion that guides users to adjust motion gestures and muscle contraction forces intentionally. The experiment results have demonstrated that hand motion recognition accuracy increases steadily along the progress of the clustering-feedback-based user training, while conventional classifier-feedback methods, i.e., label feedback, hardly achieve any improvement. The result concludes that the use of proper classifier feedback can accelerate the process of user training, and implies prosperous future for the amputees with limited or no experience in pattern-recognition-based prosthetic device manipulation.

Direct facility funding as a response to user fee reduction: implementation and perceived impact among Kenyan health centres and dispensaries

PubMed Central

Opwora, Antony; Kabare, Margaret; Molyneux, Sassy; Goodman, Catherine

2010-01-01

There is increasing pressure for reduction of user fees, but this can have adverse effects by decreasing facility-level funds. To address this, direct facility funding (DFF) was piloted in Coast Province, Kenya, with health facility committees (HFCs) responsible for managing the funds. We evaluated the implementation and perceived impact 2.5 years after DFF introduction. Quantitative data collection at 30 public health centres and dispensaries included a structured interview with the in-charge, record reviews and exit interviews. In addition, in-depth interviews were conducted with the in-charge and HFC members at 12 facilities, and with district staff and other stakeholders. DFF procedures were well established: HFCs met regularly and accounting procedures were broadly followed. DFF made an important contribution to facility cash income, accounting for 47% in health centres and 62% in dispensaries. The main items of expenditure were wages for support staff (32%), travel (21%), and construction and maintenance (18%). DFF was perceived to have a highly positive impact through funding support staff such as cleaners and patient attendants, outreach activities, renovations, patient referrals and increasing HFC activity. This was perceived to have improved health worker motivation, utilization and quality of care. A number of problems were identified. HFC training was reportedly inadequate, and no DFF documentation was available at facility level, leading to confusion. Charging user fees above those specified in the national policy remained common, and understanding of DFF among the broader community was very limited. Finally, relationships between HFCs and health workers were sometimes characterized by mistrust and resentment. Relatively small increases in funding may significantly affect facility performance when the funds are managed at the periphery. Kenya plans to scale up DFF nationwide. Our findings indicate this is warranted, but should include improved training and documentation, greater emphasis on community engagement, and insistence on user fee adherence. PMID:20211967

Direct facility funding as a response to user fee reduction: implementation and perceived impact among Kenyan health centres and dispensaries.

PubMed

Opwora, Antony; Kabare, Margaret; Molyneux, Sassy; Goodman, Catherine

2010-09-01

There is increasing pressure for reduction of user fees, but this can have adverse effects by decreasing facility-level funds. To address this, direct facility funding (DFF) was piloted in Coast Province, Kenya, with health facility committees (HFCs) responsible for managing the funds. We evaluated the implementation and perceived impact 2.5 years after DFF introduction. Quantitative data collection at 30 public health centres and dispensaries included a structured interview with the in-charge, record reviews and exit interviews. In addition, in-depth interviews were conducted with the in-charge and HFC members at 12 facilities, and with district staff and other stakeholders. DFF procedures were well established: HFCs met regularly and accounting procedures were broadly followed. DFF made an important contribution to facility cash income, accounting for 47% in health centres and 62% in dispensaries. The main items of expenditure were wages for support staff (32%), travel (21%), and construction and maintenance (18%). DFF was perceived to have a highly positive impact through funding support staff such as cleaners and patient attendants, outreach activities, renovations, patient referrals and increasing HFC activity. This was perceived to have improved health worker motivation, utilization and quality of care. A number of problems were identified. HFC training was reportedly inadequate, and no DFF documentation was available at facility level, leading to confusion. Charging user fees above those specified in the national policy remained common, and understanding of DFF among the broader community was very limited. Finally, relationships between HFCs and health workers were sometimes characterized by mistrust and resentment. Relatively small increases in funding may significantly affect facility performance when the funds are managed at the periphery. Kenya plans to scale up DFF nationwide. Our findings indicate this is warranted, but should include improved training and documentation, greater emphasis on community engagement, and insistence on user fee adherence.

An Ontology-Based Tourism Recommender System Based on Spreading Activation Model

NASA Astrophysics Data System (ADS)

Bahramian, Z.; Abbaspour, R. Ali

2015-12-01

A tourist has time and budget limitations; hence, he needs to select points of interest (POIs) optimally. Since the available information about POIs is overloading, it is difficult for a tourist to select the most appreciate ones considering preferences. In this paper, a new travel recommender system is proposed to overcome information overload problem. A recommender system (RS) evaluates the overwhelming number of POIs and provides personalized recommendations to users based on their preferences. A content-based recommendation system is proposed, which uses the information about the user's preferences and POIs and calculates a degree of similarity between them. It selects POIs, which have highest similarity with the user's preferences. The proposed content-based recommender system is enhanced using the ontological information about tourism domain to represent both the user profile and the recommendable POIs. The proposed ontology-based recommendation process is performed in three steps including: ontology-based content analyzer, ontology-based profile learner, and ontology-based filtering component. User's feedback adapts the user's preferences using Spreading Activation (SA) strategy. It shows the proposed recommender system is effective and improves the overall performance of the traditional content-based recommender systems.

A study on user authentication methodology using numeric password and fingerprint biometric information.

PubMed

Ju, Seung-hwan; Seo, Hee-suk; Han, Sung-hyu; Ryou, Jae-cheol; Kwak, Jin

2013-01-01

The prevalence of computers and the development of the Internet made us able to easily access information. As people are concerned about user information security, the interest of the user authentication method is growing. The most common computer authentication method is the use of alphanumerical usernames and passwords. The password authentication systems currently used are easy, but only if you know the password, as the user authentication is vulnerable. User authentication using fingerprints, only the user with the information that is specific to the authentication security is strong. But there are disadvantage such as the user cannot change the authentication key. In this study, we proposed authentication methodology that combines numeric-based password and biometric-based fingerprint authentication system. Use the information in the user's fingerprint, authentication keys to obtain security. Also, using numeric-based password can to easily change the password; the authentication keys were designed to provide flexibility.

A Study on User Authentication Methodology Using Numeric Password and Fingerprint Biometric Information

PubMed Central

Ju, Seung-hwan; Seo, Hee-suk; Han, Sung-hyu; Ryou, Jae-cheol

2013-01-01

The prevalence of computers and the development of the Internet made us able to easily access information. As people are concerned about user information security, the interest of the user authentication method is growing. The most common computer authentication method is the use of alphanumerical usernames and passwords. The password authentication systems currently used are easy, but only if you know the password, as the user authentication is vulnerable. User authentication using fingerprints, only the user with the information that is specific to the authentication security is strong. But there are disadvantage such as the user cannot change the authentication key. In this study, we proposed authentication methodology that combines numeric-based password and biometric-based fingerprint authentication system. Use the information in the user's fingerprint, authentication keys to obtain security. Also, using numeric-based password can to easily change the password; the authentication keys were designed to provide flexibility. PMID:24151601

Generating Personalized Web Search Using Semantic Context

PubMed Central

Xu, Zheng; Chen, Hai-Yan; Yu, Jie

2015-01-01

The “one size fits the all” criticism of search engines is that when queries are submitted, the same results are returned to different users. In order to solve this problem, personalized search is proposed, since it can provide different search results based upon the preferences of users. However, existing methods concentrate more on the long-term and independent user profile, and thus reduce the effectiveness of personalized search. In this paper, the method captures the user context to provide accurate preferences of users for effectively personalized search. First, the short-term query context is generated to identify related concepts of the query. Second, the user context is generated based on the click through data of users. Finally, a forgetting factor is introduced to merge the independent user context in a user session, which maintains the evolution of user preferences. Experimental results fully confirm that our approach can successfully represent user context according to individual user information needs. PMID:26000335

Comparing Text-based and Graphic User Interfaces for Novice and Expert Users

PubMed Central

Chen, Jung-Wei; Zhang, Jiajie

2007-01-01

Graphic User Interface (GUI) is commonly considered to be superior to Text-based User Interface (TUI). This study compares GUI and TUI in an electronic dental record system. Several usability analysis techniques compared the relative effectiveness of a GUI and a TUI. Expert users and novice users were evaluated in time required and steps needed to complete the task. A within-subject design was used to evaluate if the experience with either interface will affect task performance. The results show that the GUI interface was not better than the TUI for expert users. GUI interface was better for novice users. For novice users there was a learning transfer effect from TUI to GUI. This means a user interface is user-friendly or not depending on the mapping between the user interface and tasks. GUI by itself may or may not be better than TUI. PMID:18693811

Comparing Text-based and Graphic User Interfaces for novice and expert users.

PubMed

Chen, Jung-Wei; Zhang, Jiajie

2007-10-11

Graphic User Interface (GUI) is commonly considered to be superior to Text-based User Interface (TUI). This study compares GUI and TUI in an electronic dental record system. Several usability analysis techniques compared the relative effectiveness of a GUI and a TUI. Expert users and novice users were evaluated in time required and steps needed to complete the task. A within-subject design was used to evaluate if the experience with either interface will affect task performance. The results show that the GUI interface was not better than the TUI for expert users. GUI interface was better for novice users. For novice users there was a learning transfer effect from TUI to GUI. This means a user interface is user-friendly or not depending on the mapping between the user interface and tasks. GUI by itself may or may not be better than TUI.

The Computational Ecologist’s Toolbox

EPA Science Inventory

Computational ecology, nestled in the broader field of data science, is an interdisciplinary field that attempts to improve our understanding of complex ecological systems through the use of modern computational methods. Computational ecology is based on a union of competence in...

Toward broadband vibration energy harvesting via mechanical motion-rectification induced inertia nonlinearity

NASA Astrophysics Data System (ADS)

Liu, Mingyi; Tai, Wei-Che; Zuo, Lei

2018-07-01

Broad frequency bandwidth is a desired feature for most energy harvesting systems. Rotational electromagnetic generators are widely used in energy harvesting systems and the generator rotor is considered as an inerter. While a lot of research striving for increasing frequency bandwidth, we found out that the inerter makes the bandwidth narrow. To solve this problem, this paper proposes using inertia nonlinearity which is realized by mechanical motion rectification (MMR). The influence of the MMR on energy harvesting performance in inerter-based systems was numerically and experimentally investigated with harmonic excitations of constant displacement amplitude. Simulation is done by transforming the mechanical system to an analogous electrical system. The simulation results show that the bandwidth of the MMR based system is broader than that of the counterpart without MMR. System parameter was identified by parameter fitting and experiment was conducted to verify the numerical simulation. Moreover, in the MMR based system, the force transmitted from the harvester to the base was decreased compared to the counterpart without MMR. For excitations with constant force amplitude, MMR based energy harvesting systems also have much broader frequency bandwidth compared to the counterpart without MMR.

Review for carrageenan-based pharmaceutical biomaterials: favourable physical features versus adverse biological effects.

PubMed

Liu, Jingjing; Zhan, Xiudan; Wan, Jianbo; Wang, Yitao; Wang, Chunming

2015-05-05

Carrageenan (CRG) is a family of natural polysaccharides derived from seaweeds and has widely been used as food additives. In the past decade, owing to its attractive physicochemical properties, CRG has been developed into versatile biomaterials vehicles for drug delivery. Nevertheless, studies also emerged to reveal its adverse effects on the biological system. In this review, we critically appraise the latest literature (two thirds since 2008) on the development of CRG-based pharmaceutical vehicles and the perspective of using CRG for broader biomedical applications. We focus on how current strategies exploit the unique gelling mechanisms, strong water absorption and abundant functional groups of the three major CRG varieties. Notably, CRG-based matrices are demonstrated to increase drug loading and drug solubility, enabling release of orally administrated drugs in zero-order or in a significantly prolonged period. Other amazing features, such as pH-sensitivity and adhesive property, of CRG-based formulations are also introduced. Finally, we discuss the adverse influence of CRG on the human body and then suggest some future directions for the development of CRG-based biomaterials for broader applications in biomedicine. Copyright © 2015 Elsevier Ltd. All rights reserved.

Knowledge information management toolkit and method

DOEpatents

Hempstead, Antoinette R.; Brown, Kenneth L.

2006-08-15

A system is provided for managing user entry and/or modification of knowledge information into a knowledge base file having an integrator support component and a data source access support component. The system includes processing circuitry, memory, a user interface, and a knowledge base toolkit. The memory communicates with the processing circuitry and is configured to store at least one knowledge base. The user interface communicates with the processing circuitry and is configured for user entry and/or modification of knowledge pieces within a knowledge base. The knowledge base toolkit is configured for converting knowledge in at least one knowledge base from a first knowledge base form into a second knowledge base form. A method is also provided.

Identifying online user reputation of user-object bipartite networks

NASA Astrophysics Data System (ADS)

Liu, Xiao-Lu; Liu, Jian-Guo; Yang, Kai; Guo, Qiang; Han, Jing-Ti

2017-02-01

Identifying online user reputation based on the rating information of the user-object bipartite networks is important for understanding online user collective behaviors. Based on the Bayesian analysis, we present a parameter-free algorithm for ranking online user reputation, where the user reputation is calculated based on the probability that their ratings are consistent with the main part of all user opinions. The experimental results show that the AUC values of the presented algorithm could reach 0.8929 and 0.8483 for the MovieLens and Netflix data sets, respectively, which is better than the results generated by the CR and IARR methods. Furthermore, the experimental results for different user groups indicate that the presented algorithm outperforms the iterative ranking methods in both ranking accuracy and computation complexity. Moreover, the results for the synthetic networks show that the computation complexity of the presented algorithm is a linear function of the network size, which suggests that the presented algorithm is very effective and efficient for the large scale dynamic online systems.

E-book recommender system design and implementation based on data mining

NASA Astrophysics Data System (ADS)

Wang, Zongjiang

2011-12-01

In the knowledge explosion, rapid development of information age, how quickly the user or users interested in useful information for feedback to the user problem to be solved in this article. This paper based on data mining, association rules to the model and classification model a combination of electronic books on the recommendation of the user's neighboring users interested in e-books to target users. Introduced the e-book recommendation and the key technologies, system implementation algorithms, and implementation process, was proved through experiments that this system can help users quickly find the required e-books.

A Context-Aware Mobile User Behavior-Based Neighbor Finding Approach for Preference Profile Construction †

PubMed Central

Gao, Qian; Fu, Deqian; Dong, Xiangjun

2016-01-01

In this paper, a new approach is adopted to update the user preference profile by seeking users with similar interests based on the context obtainable for a mobile network instead of from desktop networks. The trust degree between mobile users is calculated by analyzing their behavior based on the context, and then the approximate neighbors are chosen by combining the similarity of the mobile user preference and the trust degree. The approach first considers the communication behaviors between mobile users, the mobile network services they use as well as the corresponding context information. Then a similarity degree of the preference between users is calculated with the evaluation score of a certain mobile web service provided by a mobile user. Finally, based on the time attenuation function, the users with similar preference are found, through which we can dynamically update the target user’s preference profile. Experiments are then conducted to test the effect of the context on the credibility among mobile users, the effect of time decay factors and trust degree thresholds. Simulation shows that the proposed approach outperforms two other methods in terms of Recall Ratio, Precision Ratio and Mean Absolute Error, because neither of them consider the context mobile information. PMID:26805852

Multi-agents and learning: Implications for Webusage mining.

PubMed

Lotfy, Hewayda M S; Khamis, Soheir M S; Aboghazalah, Maie M

2016-03-01

Characterization of user activities is an important issue in the design and maintenance of websites. Server weblog files have abundant information about the user's current interests. This information can be mined and analyzed therefore the administrators may be able to guide the users in their browsing activity so they may obtain relevant information in a shorter span of time to obtain user satisfaction. Web-based technology facilitates the creation of personally meaningful and socially useful knowledge through supportive interactions, communication and collaboration among educators, learners and information. This paper suggests a new methodology based on learning techniques for a Web-based Multiagent-based application to discover the hidden patterns in the user's visited links. It presents a new approach that involves unsupervised, reinforcement learning, and cooperation between agents. It is utilized to discover patterns that represent the user's profiles in a sample website into specific categories of materials using significance percentages. These profiles are used to make recommendations of interesting links and categories to the user. The experimental results of the approach showed successful user pattern recognition, and cooperative learning among agents to obtain user profiles. It indicates that combining different learning algorithms is capable of improving user satisfaction indicated by the percentage of precision, recall, the progressive category weight and F 1-measure.

GhostWriter-2.0: Product Reviews with Case-Based Support

NASA Astrophysics Data System (ADS)

Bridge, Derek; Healy, Paul

A lot of user-generated content on the Web takes the form of records of personal experiences. Case-Based Reasoning offers a way of helping one user to reuse another's experiences from the Web. In this paper, we present GhostWriter-2.0, a Case-Based Reasoning system that supports a user who is writing a product review. GhostWriter-2.0 makes suggestions to the user, in the form of short phrases that are mined from other reviews. The purpose of the suggestions is to prompt the user to write a more comprehensive and helpful review than she might otherwise have done. We explain how GhostWriter-2.0's case base is populated with relevant and helpful reviews from Amazon. We show how it extracts and scores phrases in these reviews to decide which to suggest to the user.We report a trial with real users, in which users made greater use of GhostWriter-2.0's suggested phrases than they did of phrases suggested by a system that used a more random form of selection.

7TMRmine: a Web server for hierarchical mining of 7TMR proteins

PubMed Central

Lu, Guoqing; Wang, Zhifang; Jones, Alan M; Moriyama, Etsuko N

2009-01-01

Background Seven-transmembrane region-containing receptors (7TMRs) play central roles in eukaryotic signal transduction. Due to their biomedical importance, thorough mining of 7TMRs from diverse genomes has been an active target of bioinformatics and pharmacogenomics research. The need for new and accurate 7TMR/GPCR prediction tools is paramount with the accelerated rate of acquisition of diverse sequence information. Currently available and often used protein classification methods (e.g., profile hidden Markov Models) are highly accurate for identifying their membership information among already known 7TMR subfamilies. However, these alignment-based methods are less effective for identifying remote similarities, e.g., identifying proteins from highly divergent or possibly new 7TMR families. In this regard, more sensitive (e.g., alignment-free) methods are needed to complement the existing protein classification methods. A better strategy would be to combine different classifiers, from more specific to more sensitive methods, to identify a broader spectrum of 7TMR protein candidates. Description We developed a Web server, 7TMRmine, by integrating alignment-free and alignment-based classifiers specifically trained to identify candidate 7TMR proteins as well as transmembrane (TM) prediction methods. This new tool enables researchers to easily assess the distribution of GPCR functionality in diverse genomes or individual newly-discovered proteins. 7TMRmine is easily customized and facilitates exploratory analysis of diverse genomes. Users can integrate various alignment-based, alignment-free, and TM-prediction methods in any combination and in any hierarchical order. Sixteen classifiers (including two TM-prediction methods) are available on the 7TMRmine Web server. Not only can the 7TMRmine tool be used for 7TMR mining, but also for general TM-protein analysis. Users can submit protein sequences for analysis, or explore pre-analyzed results for multiple genomes. The server currently includes prediction results and the summary statistics for 68 genomes. Conclusion 7TMRmine facilitates the discovery of 7TMR proteins. By combining prediction results from different classifiers in a multi-level filtering process, prioritized sets of 7TMR candidates can be obtained for further investigation. 7TMRmine can be also used as a general TM-protein classifier. Comparisons of TM and 7TMR protein distributions among 68 genomes revealed interesting differences in evolution of these protein families among major eukaryotic phyla. PMID:19538753

Technology-Based Innovations to Foster Personalized Healthy Lifestyles and Well-Being: A Targeted Review.

PubMed

Spanakis, Emmanouil G; Santana, Silvina; Tsiknakis, Manolis; Marias, Kostas; Sakkalis, Vangelis; Teixeira, António; Janssen, Joris H; de Jong, Henri; Tziraki, Chariklia

2016-06-24

New community-based arrangements and novel technologies can empower individuals to be active participants in their health maintenance, enabling people to control and self-regulate their health and wellness and make better health- and lifestyle-related decisions. Mobile sensing technology and health systems responsive to individual profiles combined with cloud computing can expand innovation for new types of interoperable services that are consumer-oriented and community-based. This could fuel a paradigm shift in the way health care can be, or should be, provided and received, while lessening the burden on exhausted health and social care systems. Our goal is to identify and discuss the main scientific and engineering challenges that need to be successfully addressed in delivering state-of-the-art, ubiquitous eHealth and mHealth services, including citizen-centered wellness management services, and reposition their role and potential within a broader context of diverse sociotechnical drivers, agents, and stakeholders. We review the state-of-the-art relevant to the development and implementation of eHealth and mHealth services in critical domains. We identify and discuss scientific, engineering, and implementation-related challenges that need to be overcome to move research, development, and the market forward. Several important advances have been identified in the fields of systems for personalized health monitoring, such as smartphone platforms and intelligent ubiquitous services. Sensors embedded in smartphones and clothes are making the unobtrusive recognition of physical activity, behavior, and lifestyle possible, and thus the deployment of platforms for health assistance and citizen empowerment. Similarly, significant advances are observed in the domain of infrastructure supporting services. Still, many technical problems remain to be solved, combined with no less challenging issues related to security, privacy, trust, and organizational dynamics. Delivering innovative ubiquitous eHealth and mHealth services, including citizen-centered wellness and lifestyle management services, goes well beyond the development of technical solutions. For the large-scale information and communication technology-supported adoption of healthier lifestyles to take place, crucial innovations are needed in the process of making and deploying usable empowering end-user services that are trusted and user-acceptable. Such innovations require multidomain, multilevel, transdisciplinary work, grounded in theory but driven by citizens' and health care professionals' needs, expectations, and capabilities and matched by business ability to bring innovation to the market.

Technology-Based Innovations to Foster Personalized Healthy Lifestyles and Well-Being: A Targeted Review

PubMed Central

Santana, Silvina; Tsiknakis, Manolis; Marias, Kostas; Sakkalis, Vangelis; Teixeira, António; Janssen, Joris H; de Jong, Henri; Tziraki, Chariklia

2016-01-01

Background New community-based arrangements and novel technologies can empower individuals to be active participants in their health maintenance, enabling people to control and self-regulate their health and wellness and make better health- and lifestyle-related decisions. Mobile sensing technology and health systems responsive to individual profiles combined with cloud computing can expand innovation for new types of interoperable services that are consumer-oriented and community-based. This could fuel a paradigm shift in the way health care can be, or should be, provided and received, while lessening the burden on exhausted health and social care systems. Objective Our goal is to identify and discuss the main scientific and engineering challenges that need to be successfully addressed in delivering state-of-the-art, ubiquitous eHealth and mHealth services, including citizen-centered wellness management services, and reposition their role and potential within a broader context of diverse sociotechnical drivers, agents, and stakeholders. Methods We review the state-of-the-art relevant to the development and implementation of eHealth and mHealth services in critical domains. We identify and discuss scientific, engineering, and implementation-related challenges that need to be overcome to move research, development, and the market forward. Results Several important advances have been identified in the fields of systems for personalized health monitoring, such as smartphone platforms and intelligent ubiquitous services. Sensors embedded in smartphones and clothes are making the unobtrusive recognition of physical activity, behavior, and lifestyle possible, and thus the deployment of platforms for health assistance and citizen empowerment. Similarly, significant advances are observed in the domain of infrastructure supporting services. Still, many technical problems remain to be solved, combined with no less challenging issues related to security, privacy, trust, and organizational dynamics. Conclusions Delivering innovative ubiquitous eHealth and mHealth services, including citizen-centered wellness and lifestyle management services, goes well beyond the development of technical solutions. For the large-scale information and communication technology-supported adoption of healthier lifestyles to take place, crucial innovations are needed in the process of making and deploying usable empowering end-user services that are trusted and user-acceptable. Such innovations require multidomain, multilevel, transdisciplinary work, grounded in theory but driven by citizens’ and health care professionals’ needs, expectations, and capabilities and matched by business ability to bring innovation to the market. PMID:27342137

The Influence of the Knowledge Base on the Development of Mnemonic Strategies.

ERIC Educational Resources Information Center

Ornstein, Peter A.; Naus, Mary J.

A dominant theme in cognitive psychology is that prior knowledge in long-term memory has a strong influence on an individual's cognitive processing. Citing numerous memory studies with children, knowledge base effects are presented as part of a broader picture of memory development. Using the sort/recall procedure (asking subjects to group sets of…

Introduction to the Danish Vocational Education and Training System.

ERIC Educational Resources Information Center

Ministry of Education, Copenhagen (Denmark).

Vocational education and training is a concept that covers a sandwich-type course in which school-based education alternates with firm-based training. Broader courses in Denmark include simultaneous work at companies and school training. The advantage to this system is that students do not waste time training for an occupation that they may not…

Using Analytics to Transform a Problem-Based Case Library: An Educational Design Research Approach

ERIC Educational Resources Information Center

Schmidt, Matthew; Tawfik, Andrew A.

2018-01-01

This article describes the iterative design, development, and evaluation of a case-based learning environment focusing on an ill-structured sales management problem. We discuss our processes and situate them within the broader framework of educational design research. The learning environment evolved over the course of three design phases. A…

ELM-ART--An Interactive and Intelligent Web-Based Electronic Textbook

ERIC Educational Resources Information Center

Weber, Gerhard; Brusilovsky, Peter

2016-01-01

This paper present provides a broader view on ELM-ART, one of the first Web-based Intelligent Educational systems that offered a creative combination of two different paradigms--Intelligent Tutoring and Adaptive Hypermedia technologies. The unique dual nature of ELM-ART contributed to its long life and research impact and was a result of…

Next-Generation CBE: Designing Competency-Based Education for Underprepared College Learners

ERIC Educational Resources Information Center

Girardi, Amy; Crew, Rachel

2016-01-01

Competency-based education (CBE) is widely viewed as an innovative alternative to traditional higher education, yet most programs serve only a narrow slice of the postsecondary population. Few are intended for adults who need to boost basic skills in order to succeed in college coursework. However, if designed with the needs of a broader range of…

Using Response Ratios for Meta-Analyzing Single-Case Designs with Behavioral Outcomes

ERIC Educational Resources Information Center

Pustejovsky, James E.

2018-01-01

Methods for meta-analyzing single-case designs (SCDs) are needed to inform evidence-based practice in clinical and school settings and to draw broader and more defensible generalizations in areas where SCDs comprise a large part of the research base. The most widely used outcomes in single-case research are measures of behavior collected using…

Intelligent Context-Aware and Adaptive Interface for Mobile LBS

PubMed Central

Liu, Yanhong

2015-01-01

Context-aware user interface plays an important role in many human-computer Interaction tasks of location based services. Although spatial models for context-aware systems have been studied extensively, how to locate specific spatial information for users is still not well resolved, which is important in the mobile environment where location based services users are impeded by device limitations. Better context-aware human-computer interaction models of mobile location based services are needed not just to predict performance outcomes, such as whether people will be able to find the information needed to complete a human-computer interaction task, but to understand human processes that interact in spatial query, which will in turn inform the detailed design of better user interfaces in mobile location based services. In this study, a context-aware adaptive model for mobile location based services interface is proposed, which contains three major sections: purpose, adjustment, and adaptation. Based on this model we try to describe the process of user operation and interface adaptation clearly through the dynamic interaction between users and the interface. Then we show how the model applies users' demands in a complicated environment and suggested the feasibility by the experimental results. PMID:26457077

The NCAR Research Data Archive's Hybrid Approach for Data Discovery and Access

NASA Astrophysics Data System (ADS)

Schuster, D.; Worley, S. J.

2013-12-01

The NCAR Research Data Archive (RDA http://rda.ucar.edu) maintains a variety of data discovery and access capabilities for it's 600+ dataset collections to support the varying needs of a diverse user community. In-house developed and standards-based community tools offer services to more than 10,000 users annually. By number of users the largest group is external and access the RDA through web based protocols; the internal NCAR HPC users are fewer in number, but typically access more data volume. This paper will detail the data discovery and access services maintained by the RDA to support both user groups, and show metrics that illustrate how the community is using the services. The distributed search capability enabled by standards-based community tools, such as Geoportal and an OAI-PMH access point that serves multiple metadata standards, provide pathways for external users to initially discover RDA holdings. From here, in-house developed web interfaces leverage primary discovery level metadata databases that support keyword and faceted searches. Internal NCAR HPC users, or those familiar with the RDA, may go directly to the dataset collection of interest and refine their search based on rich file collection metadata. Multiple levels of metadata have proven to be invaluable for discovery within terabyte-sized archives composed of many atmospheric or oceanic levels, hundreds of parameters, and often numerous grid and time resolutions. Once users find the data they want, their access needs may vary as well. A THREDDS data server running on targeted dataset collections enables remote file access through OPENDAP and other web based protocols primarily for external users. In-house developed tools give all users the capability to submit data subset extraction and format conversion requests through scalable, HPC based delayed mode batch processing. Users can monitor their RDA-based data processing progress and receive instructions on how to access the data when it is ready. External users are provided with RDA server generated scripts to download the resulting request output. Similarly they can download native dataset collection files or partial files using Wget or cURL based scripts supplied by the RDA server. Internal users can access the resulting request output or native dataset collection files directly from centralized file systems.

Civil commitment law, mental health services, and US homicide rates.

PubMed

Segal, Steven P

2012-09-01

The study considers whether involuntary civil comment (ICC) statute provisions are associated with homicide rates. Do statutes based solely upon dangerousness criteria versus broader ICC-criteria-i.e. "need for treatment," "protection of health and safety," and family protection-have differential associations related to their goal of reducing the frequency of homicide? State-level data were obtained from online data bases and key-informant surveys. Ordinary-least-squares and Poisson regression were used to evaluate the association between statute characteristics, mental health system characteristics, and 2004 Homicide Rates after controlling for firearm-control-law restrictiveness and social-economic-demographic-geographic-and-political indicators historically related to homicide rate variation. Poisson and OLS models, respectively, were significant: likelihood ratio χ(2) = 108.47, df = 10; p < 0.000 and Adj. R (2) = 0.72; df = 10, 25; F = 10.21; p < 0.000. Poisson results indicate that social-economic-demographic-geographic-and-political-indicators had the strongest association with state homicide rates (p < 0.000). Lower rates were associated with: broader ICC-criteria (p ≤ 0.01), fewer inpatient-bed access problems (p ≤ 0.03), and better mental health system ratings (p ≤ 0.04). OLS results indicate that social-economic-demographic-geographic-and-political indicators accounted for 25% of homicide rate variation. Broader ICC-criteria were associated with 1.42 less homicides per 100,000. Less access to psychiatric inpatient-beds and more poorly rated mental health systems were associated with increases in the homicide rates of 1.08 and 0.26 per 100,000, respectively. While social-economic-demographic-geographic-and-political indicators show the strongest association with homicide rate variation, the results show the importance and potentially preventive utility of broader ICC criteria, increased psychiatric inpatient-bed access, and better performing mental health systems as factors contributing to homicide rate variation.

Enabling Accessibility Through Model-Based User Interface Development.

PubMed

Ziegler, Daniel; Peissner, Matthias

2017-01-01

Adaptive user interfaces (AUIs) can increase the accessibility of interactive systems. They provide personalized display and interaction modes to fit individual user needs. Most AUI approaches rely on model-based development, which is considered relatively demanding. This paper explores strategies to make model-based development more attractive for mainstream developers.

Usage Analysis of a Shared Care Planning System

PubMed Central

Warren, Jim; Gu, Yulong; Humphrey, Gayl

2012-01-01

We examined the content of electronically mediated communications in a trial of shared care planning (SCP) for long-term condition management. Software supports SCP by sharing patient records and care plans among members of the multidisciplinary care team (with patient access). Our analysis focuses on a three-month period with 73 enrolled patients, 149 provider-assigned tasks, 64 clinical notes and 48 care plans with 162 plan elements. Results show that content of notes entries is often related to task assignment and that nurses are the most active users. Directions for refinement of the SCP technology are indicated, including better integration of notes, tasks and care team notifications, as well as the central role of nurses for design use cases. Broader issues are raised about workforce roles and responsibilities for SCP, integrating patient-provider and provider-provider communications, and the centrality of care plans as the key entity in mediation of the care team. PMID:23304370

High-performance scientific computing in the cloud

NASA Astrophysics Data System (ADS)

Jorissen, Kevin; Vila, Fernando; Rehr, John

2011-03-01

Cloud computing has the potential to open up high-performance computational science to a much broader class of researchers, owing to its ability to provide on-demand, virtualized computational resources. However, before such approaches can become commonplace, user-friendly tools must be developed that hide the unfamiliar cloud environment and streamline the management of cloud resources for many scientific applications. We have recently shown that high-performance cloud computing is feasible for parallelized x-ray spectroscopy calculations. We now present benchmark results for a wider selection of scientific applications focusing on electronic structure and spectroscopic simulation software in condensed matter physics. These applications are driven by an improved portable interface that can manage virtual clusters and run various applications in the cloud. We also describe a next generation of cluster tools, aimed at improved performance and a more robust cluster deployment. Supported by NSF grant OCI-1048052.

Packaging and distributing ecological data from multisite studies

NASA Technical Reports Server (NTRS)

Olson, R. J.; Voorhees, L. D.; Field, J. M.; Gentry, M. J.

1996-01-01

Studies of global change and other regional issues depend on ecological data collected at multiple study areas or sites. An information system model is proposed for compiling diverse data from dispersed sources so that the data are consistent, complete, and readily available. The model includes investigators who collect and analyze field measurements, science teams that synthesize data, a project information system that collates data, a data archive center that distributes data to secondary users, and a master data directory that provides broader searching opportunities. Special attention to format consistency is required, such as units of measure, spatial coordinates, dates, and notation for missing values. Often data may need to be enhanced by estimating missing values, aggregating to common temporal units, or adding other related data such as climatic and soils data. Full documentation, an efficient data distribution mechanism, and an equitable way to acknowledge the original source of data are also required.

Secure Enclaves: An Isolation-centric Approach for Creating Secure High Performance Computing Environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aderholdt, Ferrol; Caldwell, Blake A.; Hicks, Susan Elaine

High performance computing environments are often used for a wide variety of workloads ranging from simulation, data transformation and analysis, and complex workflows to name just a few. These systems may process data at various security levels but in so doing are often enclaved at the highest security posture. This approach places significant restrictions on the users of the system even when processing data at a lower security level and exposes data at higher levels of confidentiality to a much broader population than otherwise necessary. The traditional approach of isolation, while effective in establishing security enclaves poses significant challenges formore » the use of shared infrastructure in HPC environments. This report details current state-of-the-art in virtualization, reconfigurable network enclaving via Software Defined Networking (SDN), and storage architectures and bridging techniques for creating secure enclaves in HPC environments.« less

Toward a Sustained, Multi-disciplinary Socioeconomic Community

NASA Astrophysics Data System (ADS)

Pearlman, J.; Pearlman, F.

2014-12-01

Over the last several years the availability of geospatial data has evolved from a scarce and expensive resource, primarily provided by governmental organizations to an abundant resource, often sourced at no or minimum charge by a much broader community including citizen scientists. In an upcoming workshop (October 28/29, 2014), the consequences of the changing technology, data, and policy landscape will be examined thus evaluating the emerging new data-driven paradigms, and advancing the state-of-the-art methodologies to measure the resulting socioeconomic impacts. Providers and users of geospatial data span a broad range of multi-disciplinary areas include policy makers and analysts, financial analysts, economists, geospatial practitioners and other experts from government, academia and the private sector. This presentation will focus on the emerging plan for a sustained, multi-disciplinary community to identify and pursue exemplary use cases for further research and applications. Considerations will include the necessary outreach enablers for such a project.

The Nuclear Energy Advanced Modeling and Simulation Enabling Computational Technologies FY09 Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diachin, L F; Garaizar, F X; Henson, V E

2009-10-12

In this document we report on the status of the Nuclear Energy Advanced Modeling and Simulation (NEAMS) Enabling Computational Technologies (ECT) effort. In particular, we provide the context for ECT In the broader NEAMS program and describe the three pillars of the ECT effort, namely, (1) tools and libraries, (2) software quality assurance, and (3) computational facility (computers, storage, etc) needs. We report on our FY09 deliverables to determine the needs of the integrated performance and safety codes (IPSCs) in these three areas and lay out the general plan for software quality assurance to meet the requirements of DOE andmore » the DOE Advanced Fuel Cycle Initiative (AFCI). We conclude with a brief description of our interactions with the Idaho National Laboratory computer center to determine what is needed to expand their role as a NEAMS user facility.« less

Feminist ethics must inform practice: interventions with perinatal substance users.

PubMed

Marcellus, Lenora

2004-09-01

Substance use during pregnancy is a major health and social issue in countries around the world. Even though many health professional associations recommend a voluntary health promotion approach to treatment, some professionals and legislators have pursued mandatory treatment, or protective intervention. A feminist ethic perspective of treatment invites us to consider a broader notion of autonomy, which includes the contexts in which women live, the difficulty they often have in accessing treatment services, and their endurance of systematic oppression related to ethnicity, socioeconomics, and politics. A punitive approach to treatment is not associated with improved outcomes for the fetus; in fact, the fetus may be at greater risk as women are fearful of accessing health services. Treatment is best pursued on a common ground basis within an embodied model of maternal-fetal relationship that will help support women and at the same time help ensure fetal health.

Will housing tenure drive unequal outcomes for Consumer-Directed Care recipients?

PubMed

Cornell, Victoria

2018-06-01

Initiatives to promote consumer choice are increasingly a feature of Australian welfare policies and programs. Consumer Directed Care (CDC) for older people and the National Disability Insurance Scheme for people younger than 65 years with a disability are two examples of this move towards consumer choice in policy and program development. The ability for service users to benefit from these programs is premised on the fact that their housing is stable and suitable. Yet, there is evidence that this is not the case, and many older people and people with disabilities experience significant housing challenges and stress. This article focuses on CDC and its implications for one particular group under housing stress - low-income older renters. Might they be at risk of limited access to home care services, and what are the broader local neighbourhood implications of this policy? © 2018 AJA Inc.

Next Generation Space Interconnect Standard (NGSIS): a modular open standards approach for high performance interconnects for space

NASA Astrophysics Data System (ADS)

Collier, Charles Patrick

2017-04-01

The Next Generation Space Interconnect Standard (NGSIS) effort is a Government-Industry collaboration effort to define a set of standards for interconnects between space system components with the goal of cost effectively removing bandwidth as a constraint for future space systems. The NGSIS team has selected the ANSI/VITA 65 OpenVPXTM standard family for the physical baseline. The RapidIO protocol has been selected as the basis for the digital data transport. The NGSIS standards are developed to provide sufficient flexibility to enable users to implement a variety of system configurations, while meeting goals for interoperability and robustness for space. The NGSIS approach and effort represents a radical departure from past approaches to achieve a Modular Open System Architecture (MOSA) for space systems and serves as an exemplar for the civil, commercial, and military Space communities as well as a broader high reliability terrestrial market.

Just a preference: racialised language in the sex-seeking profiles of gay and bisexual men.

PubMed

Callander, Denton; Holt, Martin; Newman, Christy E

2012-10-01

Racialised language is a salient and contested aspect of contemporary sexual cultures, particularly in the online domain. This paper explores the ways in which gay men in Australia employ race-related language when using online sex/dating websites. Using inductive content analysis, descriptive categories were developed to identify recurrent patterns in the racialised language employed by website users. A coding framework was then constructed to identify the 'subject' (self, other or concept) of each piece of race-related content, its 'purpose' (marketing, negative or positive discrimination, commentary) and the 'position' adopted (defensive, normalised or critical). Descriptive and comparative analyses revealed differences in the ways in which members of racial groups employed racialised language online. These differences are reviewed in relation to broader discourses on Whiteness and race in Australia, as well as recent community-produced anti-racism campaigns.

Competing Logics and Healthcare

PubMed Central

Saks, Mike

2018-01-01

This paper offers a short commentary on the editorial by Mannion and Exworthy. The paper highlights the positive insights offered by their analysis into the tensions between the competing institutional logics of standardization and customization in healthcare, in part manifested in the conflict between managers and professionals, and endorses the plea of the authors for further research in this field. However, the editorial is criticized for its lack of a strong societal reference point, the comparative absence of focus on hybridization, and its failure to highlight structural factors impinging on the opposing logics in a broader neo-institutional framework. With reference to the Procrustean metaphor, it is argued that greater stress should be placed on the healthcare user in future health policy. Finally, the case of complementary and alternative medicine is set out which – while not explicitly mentioned in the editorial – most effectively concretizes the tensions at the heart of this analysis of healthcare. PMID:29626406

FORWARD: DESERTIFICATION IN THE MEDITERRANEAN REGION: A SECURITY ISSUE

EPA Science Inventory

The Workshop focused on two basic concepts: security and desertification and their linkages. Since the end of the Cold War, traditional security concepts based on national sovereignty and territorial security have increasingly been brought under review. Currently, a broader defin...

A Broader View of Immunotherapies | Center for Cancer Research

Cancer.gov

Fresh out of graduate school at Wayne State University in Michigan in 1985, Bernard Fox, Ph.D., landed a coveted fellowship with Steven Rosenberg, M.D., just as the first patients were being treated with cell-based immunotherapies at NCI.

A new species of Agaricus section Minores from China

PubMed Central

Mao-Qiang, He; Rui-Lin, Zhao

2015-01-01

Agaricus gemloides sp. nov. is characterised by its reddish brown fibrillose squamose on the pileus, relatively slender basidiome and broader basidiospores. In this article, it is introduced based on its distinguished morphological features and molecular phylogenetic position. PMID:26807303

Beam Design and User Scheduling for Nonorthogonal Multiple Access With Multiple Antennas Based on Pareto Optimality

NASA Astrophysics Data System (ADS)

Seo, Junyeong; Sung, Youngchul

2018-06-01

In this paper, an efficient transmit beam design and user scheduling method is proposed for multi-user (MU) multiple-input single-output (MISO) non-orthogonal multiple access (NOMA) downlink, based on Pareto-optimality. The proposed beam design and user scheduling method groups simultaneously-served users into multiple clusters with practical two users in each cluster, and then applies spatical zeroforcing (ZF) across clusters to control inter-cluster interference (ICI) and Pareto-optimal beam design with successive interference cancellation (SIC) to two users in each cluster to remove interference to strong users and leverage signal-to-interference-plus-noise ratios (SINRs) of interference-experiencing weak users. The proposed method has flexibility to control the rates of strong and weak users and numerical results show that the proposed method yields good performance.

Presenting quantitative information about decision outcomes: a risk communication primer for patient decision aid developers.

PubMed

Trevena, Lyndal J; Zikmund-Fisher, Brian J; Edwards, Adrian; Gaissmaier, Wolfgang; Galesic, Mirta; Han, Paul K J; King, John; Lawson, Margaret L; Linder, Suzanne K; Lipkus, Isaac; Ozanne, Elissa; Peters, Ellen; Timmermans, Danielle; Woloshin, Steven

2013-01-01

Making evidence-based decisions often requires comparison of two or more options. Research-based evidence may exist which quantifies how likely the outcomes are for each option. Understanding these numeric estimates improves patients' risk perception and leads to better informed decision making. This paper summarises current "best practices" in communication of evidence-based numeric outcomes for developers of patient decision aids (PtDAs) and other health communication tools. An expert consensus group of fourteen researchers from North America, Europe, and Australasia identified eleven main issues in risk communication. Two experts for each issue wrote a "state of the art" summary of best evidence, drawing on the PtDA, health, psychological, and broader scientific literature. In addition, commonly used terms were defined and a set of guiding principles and key messages derived from the results. The eleven key components of risk communication were: 1) Presenting the chance an event will occur; 2) Presenting changes in numeric outcomes; 3) Outcome estimates for test and screening decisions; 4) Numeric estimates in context and with evaluative labels; 5) Conveying uncertainty; 6) Visual formats; 7) Tailoring estimates; 8) Formats for understanding outcomes over time; 9) Narrative methods for conveying the chance of an event; 10) Important skills for understanding numerical estimates; and 11) Interactive web-based formats. Guiding principles from the evidence summaries advise that risk communication formats should reflect the task required of the user, should always define a relevant reference class (i.e., denominator) over time, should aim to use a consistent format throughout documents, should avoid "1 in x" formats and variable denominators, consider the magnitude of numbers used and the possibility of format bias, and should take into account the numeracy and graph literacy of the audience. A substantial and rapidly expanding evidence base exists for risk communication. Developers of tools to facilitate evidence-based decision making should apply these principles to improve the quality of risk communication in practice.

Presenting quantitative information about decision outcomes: a risk communication primer for patient decision aid developers

PubMed Central

2013-01-01

Background Making evidence-based decisions often requires comparison of two or more options. Research-based evidence may exist which quantifies how likely the outcomes are for each option. Understanding these numeric estimates improves patients’ risk perception and leads to better informed decision making. This paper summarises current “best practices” in communication of evidence-based numeric outcomes for developers of patient decision aids (PtDAs) and other health communication tools. Method An expert consensus group of fourteen researchers from North America, Europe, and Australasia identified eleven main issues in risk communication. Two experts for each issue wrote a “state of the art” summary of best evidence, drawing on the PtDA, health, psychological, and broader scientific literature. In addition, commonly used terms were defined and a set of guiding principles and key messages derived from the results. Results The eleven key components of risk communication were: 1) Presenting the chance an event will occur; 2) Presenting changes in numeric outcomes; 3) Outcome estimates for test and screening decisions; 4) Numeric estimates in context and with evaluative labels; 5) Conveying uncertainty; 6) Visual formats; 7) Tailoring estimates; 8) Formats for understanding outcomes over time; 9) Narrative methods for conveying the chance of an event; 10) Important skills for understanding numerical estimates; and 11) Interactive web-based formats. Guiding principles from the evidence summaries advise that risk communication formats should reflect the task required of the user, should always define a relevant reference class (i.e., denominator) over time, should aim to use a consistent format throughout documents, should avoid “1 in x” formats and variable denominators, consider the magnitude of numbers used and the possibility of format bias, and should take into account the numeracy and graph literacy of the audience. Conclusion A substantial and rapidly expanding evidence base exists for risk communication. Developers of tools to facilitate evidence-based decision making should apply these principles to improve the quality of risk communication in practice. PMID:24625237

Course Ontology-Based User's Knowledge Requirement Acquisition from Behaviors within E-Learning Systems

ERIC Educational Resources Information Center

Zeng, Qingtian; Zhao, Zhongying; Liang, Yongquan

2009-01-01

User's knowledge requirement acquisition and analysis are very important for a personalized or user-adaptive learning system. Two approaches to capture user's knowledge requirement about course content within an e-learning system are proposed and implemented in this paper. The first approach is based on the historical data accumulated by an…

Toward a Theory of User-Based Relevance: A Call for a New Paradigm of Inquiry.

ERIC Educational Resources Information Center

Park, Taemin Kim

1994-01-01

Discusses the need to develop the concept of user-based relevance for the benefit of users and for the meaningful development of future research in information retrieval. Characteristics of users' criteria of relevance are examined; and research methodology models are considered, including naturalistic inquiry versus scientific, or rationalistic,…

Confidentiality Protection of User Data and Adaptive Resource Allocation for Managing Multiple Workflow Performance in Service-Based Systems

ERIC Educational Resources Information Center

An, Ho

2012-01-01

In this dissertation, two interrelated problems of service-based systems (SBS) are addressed: protecting users' data confidentiality from service providers, and managing performance of multiple workflows in SBS. Current SBSs pose serious limitations to protecting users' data confidentiality. Since users' sensitive data is sent in…

A Case Study in User Support for Managing OpenSim Based Multi User Learning Environments

ERIC Educational Resources Information Center

Perera, Indika; Miller, Alan; Allison, Colin

2017-01-01

Immersive 3D Multi User Learning Environments (MULE) have shown sufficient success to warrant their consideration as a mainstream educational paradigm. These are based on 3D Multi User Virtual Environment platforms (MUVE), and although they have been used for various innovative educational projects their complex permission systems and large…

The Usability Evaluation of Fakih Method Based on Technology for Students with Hearing Difficulties: The User's Retrospective

ERIC Educational Resources Information Center

Sabdan, Muhammad Sayuti Bin; Alias, Norlidah; Jomhari, Nazean; Jamaludin, Khairul Azhar; DeWitt, Dorothy

2014-01-01

The study is aimed at evaluating the FAKIH method based on technology in teaching al-Quran, based on the user's retrospective. The participants of this study were five students selected based on hearing difficulties. The study employed the user evaluation framework. Teacher's journals were used to determine the frequency and percentage of…

Preferred reporting items for studies mapping onto preference-based outcome measures: The MAPS statement.

PubMed

Petrou, Stavros; Rivero-Arias, Oliver; Dakin, Helen; Longworth, Louise; Oppe, Mark; Froud, Robert; Gray, Alastair

2015-01-01

'Mapping' onto generic preference-based outcome measures is increasingly being used as a means of generating health utilities for use within health economic evaluations. Despite publication of technical guides for the conduct of mapping research, guidance for the reporting of mapping studies is currently lacking. The MAPS (MApping onto Preference-based measures reporting Standards) statement is a new checklist, which aims to promote complete and transparent reporting of mapping studies. The primary audiences for the MAPS statement are researchers reporting mapping studies, the funders of the research, and peer reviewers and editors involved in assessing mapping studies for publication. A de novo list of 29 candidate reporting items and accompanying explanations was created by a working group comprised of six health economists and one Delphi methodologist. Following a two-round, modified Delphi survey with representatives from academia, consultancy, health technology assessment agencies and the biomedical journal editorial community, a final set of 23 items deemed essential for transparent reporting, and accompanying explanations, was developed. The items are contained in a user friendly 23 item checklist. They are presented numerically and categorised within six sections, namely: (i) title and abstract; (ii) introduction; (iii) methods; (iv) results; (v) discussion; and (vi) other. The MAPS statement is best applied in conjunction with the accompanying MAPS explanation and elaboration document. It is anticipated that the MAPS statement will improve the clarity, transparency and completeness of reporting of mapping studies. To facilitate dissemination and uptake, the MAPS statement is being co-published by seven health economics and quality of life journals, and broader endorsement is encouraged. The MAPS working group plans to assess the need for an update of the reporting checklist in five years' time.

Preferred Reporting Items for Studies Mapping onto Preference-Based Outcome Measures: The MAPS Statement.

PubMed

Petrou, Stavros; Rivero-Arias, Oliver; Dakin, Helen; Longworth, Louise; Oppe, Mark; Froud, Robert; Gray, Alastair

2015-10-01

'Mapping' onto generic preference-based outcome measures is increasingly being used as a means of generating health utilities for use within health economic evaluations. Despite the publication of technical guides for the conduct of mapping research, guidance for the reporting of mapping studies is currently lacking. The MAPS (MApping onto Preference-based measures reporting Standards) statement is a new checklist, which aims to promote complete and transparent reporting of mapping studies. The primary audiences for the MAPS statement are researchers reporting mapping studies, the funders of the research, and peer reviewers and editors involved in assessing mapping studies for publication. A de novo list of 29 candidate reporting items and accompanying explanations was created by a working group comprising six health economists and one Delphi methodologist. Following a two-round modified Delphi survey with representatives from academia, consultancy, health technology assessment agencies and the biomedical journal editorial community, a final set of 23 items deemed essential for transparent reporting, and accompanying explanations, was developed. The items are contained in a user-friendly 23-item checklist. They are presented numerically and categorised within six sections, namely: (1) title and abstract; (2) introduction; (3) methods; (4) results; (5) discussion; and (6) other. The MAPS statement is best applied in conjunction with the accompanying MAPS explanation and elaboration document. It is anticipated that the MAPS statement will improve the clarity, transparency and completeness of reporting of mapping studies. To facilitate dissemination and uptake, the MAPS statement is being co-published by seven health economics and quality-of-life journals, and broader endorsement is encouraged. The MAPS working group plans to assess the need for an update of the reporting checklist in 5 years' time.

Medical imaging informatics based solutions for human performance analytics

NASA Astrophysics Data System (ADS)

Verma, Sneha; McNitt-Gray, Jill; Liu, Brent J.

2018-03-01

For human performance analysis, extensive experimental trials are often conducted to identify the underlying cause or long-term consequences of certain pathologies and to improve motor functions by examining the movement patterns of affected individuals. Data collected for human performance analysis includes high-speed video, surveys, spreadsheets, force data recordings from instrumented surfaces etc. These datasets are recorded from various standalone sources and therefore captured in different folder structures as well as in varying formats depending on the hardware configurations. Therefore, data integration and synchronization present a huge challenge while handling these multimedia datasets specifically for large datasets. Another challenge faced by researchers is querying large quantity of unstructured data and to design feedbacks/reporting tools for users who need to use datasets at various levels. In the past, database server storage solutions have been introduced to securely store these datasets. However, to automate the process of uploading raw files, various file manipulation steps are required. In the current workflow, this file manipulation and structuring is done manually and is not feasible for large amounts of data. However, by attaching metadata files and data dictionaries with these raw datasets, they can provide information and structure needed for automated server upload. We introduce one such system for metadata creation for unstructured multimedia data based on the DICOM data model design. We will discuss design and implementation of this system and evaluate this system with data set collected for movement analysis study. The broader aim of this paper is to present a solutions space achievable based on medical imaging informatics design and methods for improvement in workflow for human performance analysis in a biomechanics research lab.

A revisitation of TRIX for trophic status assessment in the light of the European Water Framework Directive: application to Italian coastal waters.

PubMed

Pettine, Maurizio; Casentini, Barbara; Fazi, Stefano; Giovanardi, Franco; Pagnotta, Romano

2007-09-01

The trophic status classification of coastal waters at the European scale requires the availability of harmonised indicators and procedures. The composite trophic status index (TRIX) provides useful metrics for the assessment of the trophic status of coastal waters. It was originally developed for Italian coastal waters and then applied in many European seas (Adriatic, Tyrrhenian, Baltic, Black and Northern seas). The TRIX index does not fulfil the classification procedure suggested by the WFD for two reasons: (a) it is based on an absolute trophic scale without any normalization to type-specific reference conditions; (b) it makes an ex ante aggregation of biological (Chl-a) and physico-chemical (oxygen, nutrients) quality elements, instead of an ex post integration of separate evaluations of biological and subsequent chemical quality elements. A revisitation of the TRIX index in the light of the European Water Framework Directive (WFD, 2000/60/EC) and new TRIX derived tools are presented in this paper. A number of Italian coastal sites were grouped into different types based on a thorough analysis of their hydro-morphological conditions, and type-specific reference sites were selected. Unscaled TRIX values (UNTRIX) for reference and impacted sites have been calculated and two alternative UNTRIX-based classification procedures are discussed. The proposed procedures, to be validated on a broader scale, provide users with simple tools that give an integrated view of nutrient enrichment and its effects on algal biomass (Chl-a) and on oxygen levels. This trophic evaluation along with phytoplankton indicator species and algal blooms contribute to the comprehensive assessment of phytoplankton, one of the biological quality elements in coastal waters.

Pilot-testing an adverse drug event reporting form prior to its implementation in an electronic health record.

PubMed

Chruscicki, Adam; Badke, Katherin; Peddie, David; Small, Serena; Balka, Ellen; Hohl, Corinne M

2016-01-01

Adverse drug events (ADEs), harmful unintended consequences of medication use, are a leading cause of hospital admissions, yet are rarely documented in a structured format between care providers. We describe pilot-testing structured ADE documentation fields prior to integration into an electronic medical record (EMR). We completed a qualitative study at two Canadian hospitals. Using data derived from a systematic review of the literature, we developed screen mock-ups for an ADE reporting platform, iteratively revised in participatory workshops with diverse end-user groups. We designed a paper-based form reflecting the data elements contained in the mock-ups. We distributed them to a convenience sample of clinical pharmacists, and completed ethnographic workplace observations while the forms were used. We reviewed completed forms, collected feedback from pharmacists using semi-structured interviews, and coded the data in NVivo for themes related to the ADE form. We completed 25 h of clinical observations, and 24 ADEs were documented. Pharmacists perceived the form as simple and clear, with sufficient detail to capture ADEs. They identified fields for omission, and others requiring more detail. Pharmacists encountered barriers to documenting ADEs including uncertainty about what constituted a reportable ADE, inability to complete patient follow-up, the need for inter-professional communication to rule out alternative diagnoses, and concern about creating a permanent record. Paper-based pilot-testing allowed planning for important modifications in an ADE documentation form prior to implementation in an EMR. While paper-based piloting is rarely reported prior to EMR implementations, it can inform design and enhance functionality. Piloting with other groups of care providers and in different healthcare settings will likely lead to further revisions prior to broader implementations.

Science Partnerships Enabling Rapid Response: Designing a Strategy for Improving Scientific Collaboration during Crisis Response

NASA Astrophysics Data System (ADS)

Mease, L.; Gibbs, T.; Adiseshan, T.

2014-12-01

The 2010 Deepwater Horizon disaster required unprecedented engagement and collaboration with scientists from multiple disciplines across government, academia, and industry. Although this spurred the rapid advancement of valuable new scientific knowledge and tools, it also exposed weaknesses in the system of information dissemination and exchange among the scientists from those three sectors. Limited government communication with the broader scientific community complicated the rapid mobilization of the scientific community to assist with spill response, evaluation of impact, and public perceptions of the crisis. The lessons and new laws produced from prior spills such as Exxon Valdez were helpful, but ultimately did not lead to the actions necessary to prepare a suitable infrastructure that would support collaboration with non-governmental scientists. As oil demand pushes drilling into increasingly extreme environments, addressing the challenge of effective, science-based disaster response is an imperative. Our study employs a user-centered design process to 1) understand the obstacles to and opportunity spaces for effective scientific collaboration during environmental crises such as large oil spills, 2) identify possible tools and strategies to enable rapid information exchange between government responders and non-governmental scientists from multiple relevant disciplines, and 3) build a network of key influencers to secure sufficient buy-in for scaled implementation of appropriate tools and strategies. Our methods include user ethnography, complex system mapping, individual and system behavioral analysis, and large-scale system design to identify and prototype a solution to this crisis collaboration challenge. In this talk, we will present out insights gleaned from existing analogs of successful scientific collaboration during crises and our initial findings from the 60 targeted interviews we conducted that highlight key collaboration challenges that government agencies, academic research institutions, and industry scientists face during oil spill crises. We will also present a synthesis of leverage points in the system that may amplify the impact of an improved collaboration strategy among scientific stakeholders.

The development of a framework for high-quality, sustainable and accessible rural private therapy under the Australian National Disability Insurance Scheme.

PubMed

Dew, Angela; Barton, Rebecca; Ragen, Jo; Bulkeley, Kim; Iljadica, Alexandra; Chedid, Rebecca; Brentnall, Jennie; Bundy, Anita; Lincoln, Michelle; Gallego, Gisselle; Veitch, Craig

2016-12-01

The Australian National Disability Insurance Scheme (NDIS) will provide people with individual funding with which to purchase services such as therapy from private providers. This study developed a framework to support rural private therapists to meet the anticipated increase in demand. The study consisted of three stages utilizing focus groups, interviews and an online expert panel. Participants included private therapists delivering services in rural New South Wales (n = 28), disability service users (n = 9) and key representatives from a range of relevant consumer and service organizations (n = 16). We conducted a thematic analysis of focus groups and interview data and developed a draft framework which was subsequently refined based on feedback from stakeholders. The framework highlights the need for a 'rural-proofed' policy context in which service users, therapists and communities engage collaboratively in a therapy pathway. This collaborative engagement is supported by enablers, including networks, resources and processes which are influenced by the drivers of time, cost, opportunity and motivation. The framework identifies factors that will facilitate delivery of high-quality, sustainable, individualized private therapy services for people with a disability in rural Australia under the NDIS and emphasizes the need to reconceptualize the nature of private therapy service delivery. Implications for Rehabilitation Rural private therapists need upskilling to work with individuals with disability who have individual funding such as that provided by the Australian National Disability Insurance Scheme. Therapists working in rural communities need to consider alternative ways of delivering therapy to individuals with disability beyond the traditional one-on-one therapy models. Rural private therapists need support to work collaboratively with individuals with disability and the local community. Rural private therapists should harness locally available and broader networks, resources and processes to meet the needs and goals of individuals with disability.

Barriers and facilitators to recruitment in mental health services: care coordinators' expectations and experience of referring to a psychosis research trial.

PubMed

Bucci, Sandra; Butcher, Isabelle; Hartley, Samantha; Neil, Sandra T; Mulligan, John; Haddock, Gillian

2015-09-01

High-quality research trials are necessary to provide evidence for the effective management of mental health difficulties, but successful recruitment can be challenging. This qualitative study examines the perceived barriers and facilitators to referring mental health service users to research trials. Seven care coordinators (n = 7) who facilitated the recruitment of participants to a cognitive behaviour therapy - informed psychosis intervention trial were interviewed. Demographic information was collected by questionnaire and a semi-structured guide was used to explore barriers and facilitators to referring to a partially randomized participant preference trial. Qualitative data were thematically analysed. Four key themes, each with a number of sub-themes, were identified: (1) engage the care coordinator in the recruitment process, (2) barriers to referring to research studies, (3) facilitators to referring to research studies; (4) organisational constraints impact on implementing research outcomes into routine clinical practice. Understanding the barriers and facilitators to recruitment in mental health research could improve recruitment strategies. Our findings highlight the need for researchers' to closely consider their recruitment strategies as service users are not always given the choice to participate in research. Several key recommendations are made based on these findings in order to maximize successful recruitment to research studies. Overall, we recommend that researchers' adopt a flexible, tailor-made approach for each clinical team to ensure a collaborative relationship is developed between research staff and clinicians. A qualitative approach to understanding recruitment challenges provides a useful opportunity to explore the barriers and facilitators to recruiting participants to research studies. These findings have practical implications that highlight the need for a collaborative partnership between researchers and clinical services. Understanding the challenges and issues related to recruitment can help researchers consider strategies to overcome recruitment issues. More research with a larger sample, across a broader population and in different mental health services is required. © 2014 The British Psychological Society.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gougar, Hans

This document outlines the development of a high fidelity, best estimate nuclear power plant severe transient simulation capability that will complement or enhance the integral system codes historically used for licensing and analysis of severe accidents. As with other tools in the Risk Informed Safety Margin Characterization (RISMC) Toolkit, the ultimate user of Enhanced Severe Transient Analysis and Prevention (ESTAP) capability is the plant decision-maker; the deliverable to that customer is a modern, simulation-based safety analysis capability, applicable to a much broader class of safety issues than is traditional Light Water Reactor (LWR) licensing analysis. Currently, the RISMC pathway’s majormore » emphasis is placed on developing RELAP-7, a next-generation safety analysis code, and on showing how to use RELAP-7 to analyze margin from a modern point of view: that is, by characterizing margin in terms of the probabilistic spectra of the “loads” applied to systems, structures, and components (SSCs), and the “capacity” of those SSCs to resist those loads without failing. The first objective of the ESTAP task, and the focus of one task of this effort, is to augment RELAP-7 analyses with user-selected multi-dimensional, multi-phase models of specific plant components to simulate complex phenomena that may lead to, or exacerbate, severe transients and core damage. Such phenomena include: coolant crossflow between PWR assemblies during a severe reactivity transient, stratified single or two-phase coolant flow in primary coolant piping, inhomogeneous mixing of emergency coolant water or boric acid with hot primary coolant, and water hammer. These are well-documented phenomena associated with plant transients but that are generally not captured in system codes. They are, however, generally limited to specific components, structures, and operating conditions. The second ESTAP task is to similarly augment a severe (post-core damage) accident integral analyses code with high fidelity simulations that would allow investigation of multi-dimensional, multi-phase containment phenomena that are only treated approximately in established codes.« less

A Mobile Food Record For Integrated Dietary Assessment*

PubMed Central

Ahmad, Ziad; Kerr, Deborah A.; Bosch, Marc; Boushey, Carol J.; Delp, Edward J.; Khanna, Nitin; Zhu, Fengqing

2017-01-01

This paper presents an integrated dietary assessment system based on food image analysis that uses mobile devices or smartphones. We describe two components of our integrated system: a mobile application and an image-based food nutrient database that is connected to the mobile application. An easy-to-use mobile application user interface is described that was designed based on user preferences as well as the requirements of the image analysis methods. The user interface is validated by user feedback collected from several studies. Food nutrient and image databases are also described which facilitates image-based dietary assessment and enable dietitians and other healthcare professionals to monitor patients dietary intake in real-time. The system has been tested and validated in several user studies involving more than 500 users who took more than 60,000 food images under controlled and community-dwelling conditions. PMID:28691119

Systems Engineering Model and Training Application for Desktop Environment

NASA Technical Reports Server (NTRS)

May, Jeffrey T.

2010-01-01

Provide a graphical user interface based simulator for desktop training, operations and procedure development and system reference. This simulator allows for engineers to train and further understand the dynamics of their system from their local desktops. It allows the users to train and evaluate their system at a pace and skill level based on the user's competency and from a perspective based on the user's need. The simulator will not require any special resources to execute and should generally be available for use. The interface is based on a concept of presenting the model of the system in ways that best suits the user's application or training needs. The three levels of views are Component View, the System View (overall system), and the Console View (monitor). These views are portals into a single model, so changing the model from one view or from a model manager Graphical User Interface will be reflected on all other views.

Cognitive radio based optimal channel sensing and resources allocation

NASA Astrophysics Data System (ADS)

Vijayasarveswari, V.; Khatun, S.; Fakir, M. M.; Nayeem, M. N.; Kamarudin, L. M.; Jakaria, A.

2017-03-01

Cognitive radio (CR) is the latest type of wireless technoloy that is proposed to mitigate spectrum saturation problem. İn cognitve radio, secondary user will use primary user's spectrum during primary user's absence without interupting primary user's transmission. This paper focuses on practical cognitive radio network development process using Android based smart phone for the data transmission. Energy detector based sensing method was proposed and used here because it doesnot require primary user's information. Bluetooth and Wi-fi are the two available types of spectrum that was sensed for CR detection. Simulation showed cognitive radio network can be developed using Android based smart phones. So, a complete application was developed using Java based Android Eclipse program. Finally, the application was uploaded and run on Android based smart phone to form and verify CR network for channel sensing and resource allocation. The observed efficiency of the application was around 81%.

Scheduling Algorithms for Maximizing Throughput with Zero-Forcing Beamforming in a MIMO Wireless System

NASA Astrophysics Data System (ADS)

Foronda, Augusto; Ohta, Chikara; Tamaki, Hisashi

Dirty paper coding (DPC) is a strategy to achieve the region capacity of multiple input multiple output (MIMO) downlink channels and a DPC scheduler is throughput optimal if users are selected according to their queue states and current rates. However, DPC is difficult to implement in practical systems. One solution, zero-forcing beamforming (ZFBF) strategy has been proposed to achieve the same asymptotic sum rate capacity as that of DPC with an exhaustive search over the entire user set. Some suboptimal user group selection schedulers with reduced complexity based on ZFBF strategy (ZFBF-SUS) and proportional fair (PF) scheduling algorithm (PF-ZFBF) have also been proposed to enhance the throughput and fairness among the users, respectively. However, they are not throughput optimal, fairness and throughput decrease if each user queue length is different due to different users channel quality. Therefore, we propose two different scheduling algorithms: a throughput optimal scheduling algorithm (ZFBF-TO) and a reduced complexity scheduling algorithm (ZFBF-RC). Both are based on ZFBF strategy and, at every time slot, the scheduling algorithms have to select some users based on user channel quality, user queue length and orthogonality among users. Moreover, the proposed algorithms have to produce the rate allocation and power allocation for the selected users based on a modified water filling method. We analyze the schedulers complexity and numerical results show that ZFBF-RC provides throughput and fairness improvements compared to the ZFBF-SUS and PF-ZFBF scheduling algorithms.

Gold-reflector-based semiconductor saturable absorber mirror for femtosecond mode-locked Cr4+:YAG lasers

NASA Astrophysics Data System (ADS)

Zhang, Z.; Nakagawa, T.; Torizuka, K.; Sugaya, T.; Kobayashi, K.

We developed a gold reflector based semiconductor saturable absorber mirror that has a sufficiently high reflectivity and a broad bandwidth and has been used to initiate the mode locking in a Cr4+:YAG laser. The laser achieved a similar efficiency to the lasers with Bragg-reflector-based semiconductor saturable absorber mirrors, but delivered a much broader spectrum and a shorter pulse.

Unsupervised user similarity mining in GSM sensor networks.

PubMed

Shad, Shafqat Ali; Chen, Enhong

2013-01-01

Mobility data has attracted the researchers for the past few years because of its rich context and spatiotemporal nature, where this information can be used for potential applications like early warning system, route prediction, traffic management, advertisement, social networking, and community finding. All the mentioned applications are based on mobility profile building and user trend analysis, where mobility profile building is done through significant places extraction, user's actual movement prediction, and context awareness. However, significant places extraction and user's actual movement prediction for mobility profile building are a trivial task. In this paper, we present the user similarity mining-based methodology through user mobility profile building by using the semantic tagging information provided by user and basic GSM network architecture properties based on unsupervised clustering approach. As the mobility information is in low-level raw form, our proposed methodology successfully converts it to a high-level meaningful information by using the cell-Id location information rather than previously used location capturing methods like GPS, Infrared, and Wifi for profile mining and user similarity mining.

Better Broader Impacts through National Science Foundation Centers

NASA Astrophysics Data System (ADS)

Campbell, K. M.

2010-12-01

National Science Foundation Science and Technology Centers (STCs) play a leading role in developing and evaluating “Better Broader Impacts”; best practices for recruiting a broad spectrum of American students into STEM fields and for educating these future professionals, as well as their families, teachers and the general public. With staff devoted full time to Broader Impacts activities, over the ten year life of a Center, STCs are able to address both a broad range of audiences and a broad range of topics. Along with other NSF funded centers, such as Centers for Ocean Sciences Education Excellence, Engineering Research Centers and Materials Research Science and Engineering Centers, STCs develop both models and materials that individual researchers can adopt, as well as, in some cases, direct opportunities for individual researchers to offer their disciplinary research expertise to existing center Broader Impacts Programs. The National Center for Earth-surface Dynamics is an STC headquartered at the University of Minnesota. NCED’s disciplinary research spans the physical, biological and engineering issues associated with developing an integrative, quantitative and predictive understanding of rivers and river basins. Funded in 2002, we have had the opportunity to partner with individuals and institutions ranging from formal to informal education and from science museums to Tribal and women’s colleges. We have developed simple table top physical models, complete museum exhibitions, 3D paper maps and interactive computer based visualizations, all of which have helped us communicate with this wide variety of learners. Many of these materials themselves or plans to construct them are available online; in many cases they have also been formally evaluated. We have also listened to the formal and informal educators with whom we partner, from whom we have learned a great deal about how to design Broader Impacts activities and programs. Using NCED as a case study, this session showcases NCED’s materials, approaches and lessons learned. We will also introduce the work of our sister STCs, whose disciplines span the STEM fields.

User participation is a family matter: A multiple case study of the experiences of older, hospitalised people and their relatives.

PubMed

Nyborg, Ingrid; Danbolt, Lars J; Kirkevold, Marit

2017-12-01

The purpose of this multiple case study was to compare and contrast older people's and their relatives' experiences of participation in decision-making processes regarding the planning of everyday life after discharge from hospital. Internationally, patient involvement in health services is established to benefit patient health and to improve quality of the services. The literature shows that at hospital discharge, older people would benefit from better communication and more active participation of relatives in the discharge planning. Little research has been carried out on the experiences of patients and relatives as a family in this context, and even less has investigated their participation. This study used a qualitative design with a comparative multicase approach. Participants were recruited from two hospitals in Norway using a purposive sampling strategy. Semi-structured interviews were conducted with five patients and with six of their relatives. Three patterns of experiences were identified: contradicting experiences; consistent experiences of nonpreferred participation; similar, but separate experiences of user participation. User participation in the planning of everyday life following discharge appeared to be random and limited for both patients and their relatives, and conflicting for the families as a whole. The decision-making processes seemed to be limited to the hospital context and did not include the broader context of everyday life following discharge. The results underscore the importance of taking a family perspective when caring for older people. Family meetings might be a useful tool to ensure systematic assessment and integration of the perspectives of both older people and their family in the planning of follow-up care. © 2017 The Authors. Journal of Clinical Nursing Published by John Wiley & Sons Ltd.

An Assessment of the Need for Standard Variable Names for Airborne Field Campaigns

NASA Astrophysics Data System (ADS)

Beach, A. L., III; Chen, G.; Northup, E. A.; Kusterer, J.; Quam, B. M.

2017-12-01

The NASA Earth Venture Program has led to a dramatic increase in airborne observations, requiring updated data management practices with clearly defined data standards and protocols for metadata. An airborne field campaign can involve multiple aircraft and a variety of instruments. It is quite common to have different instruments/techniques measure the same parameter on one or more aircraft platforms. This creates a need to allow instrument Principal Investigators (PIs) to name their variables in a way that would distinguish them across various data sets. A lack of standardization of variables names presents a challenge for data search tools in enabling discovery of similar data across airborne studies, aircraft platforms, and instruments. This was also identified by data users as one of the top issues in data use. One effective approach for mitigating this problem is to enforce variable name standardization, which can effectively map the unique PI variable names to fixed standard names. In order to ensure consistency amongst the standard names, it will be necessary to choose them from a controlled list. However, no such list currently exists despite a number of previous efforts to establish a sufficient list of atmospheric variable names. The Atmospheric Composition Variable Standard Name Working Group was established under the auspices of NASA's Earth Science Data Systems Working Group (ESDSWG) to solicit research community feedback to create a list of standard names that are acceptable to data providers and data users This presentation will discuss the challenges and recommendations of standard variable names in an effort to demonstrate how airborne metadata curation/management can be improved to streamline data ingest, improve interoperability, and discoverability to a broader user community.

Fostering successful scientific software communities

NASA Astrophysics Data System (ADS)

Bangerth, W.; Heister, T.; Hwang, L.; Kellogg, L. H.

2016-12-01

Developing sustainable open source software packages for the sciences appears at first to be primarily a technical challenge: How can one create stable and robust algorithms, appropriate software designs, sufficient documentation, quality assurance strategies such as continuous integration and test suites, or backward compatibility approaches that yield high-quality software usable not only by the authors, but also the broader community of scientists? However, our experience from almost two decades of leading the development of the deal.II software library (http://www.dealii.org, a widely-used finite element package) and the ASPECT code (http://aspect.dealii.org, used to simulate convection in the Earth's mantle) has taught us that technical aspects are not the most difficult ones in scientific open source software. Rather, it is the social challenge of building and maintaining a community of users and developers interested in answering questions on user forums, contributing code, and jointly finding solutions to common technical and non-technical challenges. These problems are posed in an environment where project leaders typically have no resources to reward the majority of contributors, where very few people are specifically paid for the work they do on the project, and with frequent turnover of contributors as project members rotate into and out of jobs. In particular, much software work is done by graduate students who may become fluent enough in a software only a year or two before they leave academia. We will discuss strategies we have found do and do not work in maintaining and growing communities around the scientific software projects we lead. Specifically, we will discuss the management style necessary to keep contributors engaged, ways to give credit where credit is due, and structuring documentation to decrease reliance on forums and thereby allow user communities to grow without straining those who answer questions.

A Generalized Framework for Non-Stationary Extreme Value Analysis

NASA Astrophysics Data System (ADS)

Ragno, E.; Cheng, L.; Sadegh, M.; AghaKouchak, A.

2017-12-01

Empirical trends in climate variables including precipitation, temperature, snow-water equivalent at regional to continental scales are evidence of changes in climate over time. The evolving climate conditions and human activity-related factors such as urbanization and population growth can exert further changes in weather and climate extremes. As a result, the scientific community faces an increasing demand for updated appraisal of the time-varying climate extremes. The purpose of this study is to offer a robust and flexible statistical tool for non-stationary extreme value analysis which can better characterize the severity and likelihood of extreme climatic variables. This is critical to ensure a more resilient environment in a changing climate. Following the positive feedback on the first version of Non-Stationary Extreme Value Analysis (NEVA) Toolbox by Cheng at al. 2014, we present an improved version, i.e. NEVA2.0. The upgraded version herein builds upon a newly-developed hybrid evolution Markov Chain Monte Carlo (MCMC) approach for numerical parameters estimation and uncertainty assessment. This addition leads to a more robust uncertainty estimates of return levels, return periods, and risks of climatic extremes under both stationary and non-stationary assumptions. Moreover, NEVA2.0 is flexible in incorporating any user-specified covariate other than the default time-covariate (e.g., CO2 emissions, large scale climatic oscillation patterns). The new feature will allow users to examine non-stationarity of extremes induced by physical conditions that underlie the extreme events (e.g. antecedent soil moisture deficit, large-scale climatic teleconnections, urbanization). In addition, the new version offers an option to generate stationary and/or non-stationary rainfall Intensity - Duration - Frequency (IDF) curves that are widely used for risk assessment and infrastructure design. Finally, a Graphical User Interface (GUI) of the package is provided, making NEVA accessible to a broader audience.

AOIPS data base management systems support for GARP data sets

NASA Technical Reports Server (NTRS)

Gary, J. P.

1977-01-01

A data base management system is identified, developed to provide flexible access to data sets produced by GARP during its data systems tests. The content and coverage of the data base are defined and a computer-aided, interactive information storage and retrieval system, implemented to facilitate access to user specified data subsets, is described. The computer programs developed to provide the capability were implemented on the highly interactive, minicomputer-based AOIPS and are referred to as the data retrieval system (DRS). Implemented as a user interactive but menu guided system, the DRS permits users to inventory the data tape library and create duplicate or subset data sets based on a user selected window defined by time and latitude/longitude boundaries. The DRS permits users to select, display, or produce formatted hard copy of individual data items contained within the data records.

User interface and patient involvement.

PubMed

Andreassen, Hege Kristin; Lundvoll Nilsen, Line

2013-01-01

Increased patient involvement is a goal in contemporary health care, and of importance to the development of patient oriented ICT. In this paper we discuss how the design of patient-user interfaces can affect patient involvement. Our discussion is based on 12 semi-structured interviews with patient users of a web-based solution for patient--doctor communication piloted in Norway. We argue ICT solutions offering a choice of user interfaces on the patient side are preferable to ensure individual accommodation and a high degree of patient involvement. When introducing web-based tools for patient--health professional communication a free-text option should be provided to the patient users.

Policy and programmatic considerations for introducing a longer-acting injectable contraceptive: perspectives of stakeholders from Kenya and Rwanda

PubMed Central

McKenna, Kevin; Arcara, Jennet; Rademacher, Kate H; Mackenzie, Caroline; Ngabo, Fidele; Munyambanza, Emmanuel; Wesson, Jennifer; Tolley, Elizabeth E

2014-01-01

ABSTRACT Background: More than 40 million women use injectable contraceptives to prevent pregnancy, and most current or previous injectable users report being satisfied with the method. However, while women may find injectables acceptable, they may not always find them accessible due to stock-outs and difficulties with returning to the clinic for reinjections. FHI 360 is spearheading efforts to develop a longer-acting injectable (LAI) contraceptive that could provide at least 6 months of protection against pregnancy. This article addresses systems-level considerations for the introduction of a new LAI. Methods: We conducted qualitative case studies in Kenya and Rwanda—two countries that have high levels of injectable use but with different service delivery contexts. Between June and September 2012, we conducted in-depth interviews with 27 service providers and 19 policy makers and program implementers focusing on 4 themes: systems-level barriers and facilitators to delivering LAI services; process for introducing an LAI; LAI distribution approaches; and potential LAI characteristics. We also obtained electronic feedback from 28 international family planning opinion leaders. Results: Respondents indicated strong interest in an LAI and thought it would appeal to existing injectable users as well as new family planning clients, both for spacing and for limiting births. Providers appreciated the potential for a lighter workload due to fewer follow-up visits, but they were concerned that fewer visits would also decrease their ability to help women manage side effects. The providers also appreciated the 1-month grace period for follow-up LAI injections; some seemed unaware of the latest international guidance that had increased the grace period from 2 weeks to 4 weeks for the currently available 3-month injectable. The majority of policy makers and program implementers were supportive of letting community health workers provide the method, but many nurses and midwives in Kenya had reservations about the approach. At the policy level, respondents indicated that obtaining regulatory approvals before introducing the new method could be costly and time-consuming. Manufacturing and procurement decisions could also affect cost and availability. Conclusions: Successful introduction of a potential longer-acting injectable may be enhanced by considering broader systemic issues, including managing cost to the health system and users, expanding access through community-based distribution, and training providers on the latest service delivery guidelines. PMID:25611479

GeoMapApp as a platform for visualizing marine data from Polar Regions

NASA Astrophysics Data System (ADS)

Nitsche, F. O.; Ryan, W. B.; Carbotte, S. M.; Ferrini, V.; Goodwillie, A. M.; O'hara, S. H.; Weissel, R.; McLain, K.; Chinhong, C.; Arko, R. A.; Chan, S.; Morton, J. J.; Pomeroy, D.

2012-12-01

To maximize the investment in expensive fieldwork the resulting data should be re-used as much as possible. In addition, unnecessary duplication of data collection effort should be avoided. This becomes even more important if access to field areas is as difficult and expensive as it is in Polar Regions. Making existing data discoverable in an easy to use platform is key to improve re-use and avoid duplication. A common obstacle is that use of existing data is often limited to specialists who know of the data existence and also have the right tools to view and analyze these data. GeoMapApp is a free, interactive, map based tool that allows users to discover, visualize, and analyze a large number of data sets. In addition to a global view, it provides polar map projections for displaying data in Arctic and Antarctic areas. Data that have currently been added to the system include Arctic swath bathymetry data collected from the USCG icebreaker Healy. These data are collected almost continuously including from cruises where bathymetry is not the main objective and for which existence of the acquired data may not be well known. In contrast, existence of seismic data from the Antarctic continental margin is well known in the seismic community. They are archived at and can be accessed through the Antarctic Seismic Data Library System (SDLS). Incorporating these data into GeoMapApp makes an even broader community aware of these data and the custom interface, which includes capabilities to visualize and explore these data, allows users without specific software or knowledge of the underlying data format to access the data. In addition to investigating these datasets, GeoMapApp provides links to the actual data sources to allow specialists the opportunity to re-use the original data. Important identification of data sources and data references are achieved on different levels. For access to the actual Antarctic seismic data GeoMapApp links to the SDLS site, where users have to register before downloading the data and where they are informed about data owners. For the swath bathymetry data GeoMapApp links to an IEDA/MGDS web page for each cruise containing detailed information about investigators and surveys.

Commentary: the value of PrEP for people who inject drugs.

PubMed

Coleman, Rosalind L; McLean, Susie

2016-01-01

The offer of pre-exposure prophylaxis (PrEP) is recommended as an additional option for HIV prevention for people at substantial risk of HIV infection as part of combination HIV prevention approaches. Implementing this depends on integrating PrEP in public health programmes that address risky practices with evidence-based interventions, and that operate in an enabling legal and policy environment for the delivery of health services to those at higher risk of HIV infection. What does this recommendation mean in terms of the diverse range of HIV prevention needs of key populations, some of whom are so discriminated against that they exist essentially outside formal systems such as national public health services, and for whom a substantial risk of HIV is part of a larger adverse and hostile situation? We discuss this question with reference to people who inject drugs, informed by concerns and comments that emerged from a series of consultations. HIV prevention is part of a spectrum of injecting drug users' priorities, and their access and uptake of HIV prevention services is contingent on their wider "risk environment." The need to address structural barriers to services and human rights violations, and to improve access to comprehensive harm reduction programmes are of prime importance and would have higher value than a mono-focus on HIV prevention. Where existing harm reduction activities are inadequate, fragile or dependent on external donors, shifts in funding priorities, including, for example, towards PrEP, could threaten investment in the broader programmes. For these reasons, it cannot be assumed that PrEP promotion will always be supported by people who inject drugs.The sexual partners of people who inject drugs, non-opioid users who also inject and for whom there is no established substitution treatment, as well as drug users who are unable to negotiate safe sex may value PrEP. As for all key populations, the involvement of people who inject drugs in shaping services for their consumption is vital and too often ignored. For people who inject drugs and who experience discrimination, violence or harassment, implementation of PrEP should be guided by understanding and engaging with their interconnected range of needs, risk practices, priorities and options. The differentiated needs of sub-populations that inject a range of drugs, and their sexual partners, require further exploration.

Interpreting megalithic tomb orientation and siting within broader cultural contexts

NASA Astrophysics Data System (ADS)

Prendergast, Frank

2016-02-01

This paper assesses the measured axial orientations and siting of Irish passage tombs. The distribution of monuments with passages/entrances directed at related tombs/cairns is shown. Where this phenomenon occurs, the targeted structure is invariably located at a higher elevation on the skyline and this could suggest a symbolic and hierarchical relationship in their relative siting in the landscape. Additional analysis of astronomical declinations at a national scale has identified tombs with an axial alignment towards the rising and setting positions of the Sun at the winter and summer solstices. A criteria-based framework is developed which potentially allows for these types of data to be more meaningfully considered and culturally interpreted within broader archaeological and social anthropological contexts.

Dynamic Distribution and Layouting of Model-Based User Interfaces in Smart Environments

NASA Astrophysics Data System (ADS)

Roscher, Dirk; Lehmann, Grzegorz; Schwartze, Veit; Blumendorf, Marco; Albayrak, Sahin

The developments in computer technology in the last decade change the ways of computer utilization. The emerging smart environments make it possible to build ubiquitous applications that assist users during their everyday life, at any time, in any context. But the variety of contexts-of-use (user, platform and environment) makes the development of such ubiquitous applications for smart environments and especially its user interfaces a challenging and time-consuming task. We propose a model-based approach, which allows adapting the user interface at runtime to numerous (also unknown) contexts-of-use. Based on a user interface modelling language, defining the fundamentals and constraints of the user interface, a runtime architecture exploits the description to adapt the user interface to the current context-of-use. The architecture provides automatic distribution and layout algorithms for adapting the applications also to contexts unforeseen at design time. Designers do not specify predefined adaptations for each specific situation, but adaptation constraints and guidelines. Furthermore, users are provided with a meta user interface to influence the adaptations according to their needs. A smart home energy management system serves as running example to illustrate the approach.

Reclaiming Our "Toughest" Youth

ERIC Educational Resources Information Center

Gharabaghi, Kiaras

2008-01-01

Some so-called "evidence-based" interventions are narrow methods which are justified by some quantitative research. This limited focus ignores broader qualitative studies showing that interpersonal relationships wield more impact than technique. Even a cursory review of youth-serving organizations demonstrates that the overwhelming majority of…

A Randomized Trial Comparing Classical Participatory Design to VandAID, an Interactive CrowdSourcing Platform to Facilitate User-centered Design.

PubMed

Dufendach, Kevin R; Koch, Sabine; Unertl, Kim M; Lehmann, Christoph U

2017-10-26

Early involvement of stakeholders in the design of medical software is particularly important due to the need to incorporate complex knowledge and actions associated with clinical work. Standard user-centered design methods include focus groups and participatory design sessions with individual stakeholders, which generally limit user involvement to a small number of individuals due to the significant time investments from designers and end users. The goal of this project was to reduce the effort for end users to participate in co-design of a software user interface by developing an interactive web-based crowdsourcing platform. In a randomized trial, we compared a new web-based crowdsourcing platform to standard participatory design sessions. We developed an interactive, modular platform that allows responsive remote customization and design feedback on a visual user interface based on user preferences. The responsive canvas is a dynamic HTML template that responds in real time to user preference selections. Upon completion, the design team can view the user's interface creations through an administrator portal and download the structured selections through a REDCap interface. We have created a software platform that allows users to customize a user interface and see the results of that customization in real time, receiving immediate feedback on the impact of their design choices. Neonatal clinicians used the new platform to successfully design and customize a neonatal handoff tool. They received no specific instruction and yet were able to use the software easily and reported high usability. VandAID, a new web-based crowdsourcing platform, can involve multiple users in user-centered design simultaneously and provides means of obtaining design feedback remotely. The software can provide design feedback at any stage in the design process, but it will be of greatest utility for specifying user requirements and evaluating iterative designs with multiple options.

Shilling attack detection for recommender systems based on credibility of group users and rating time series.

PubMed

Zhou, Wei; Wen, Junhao; Qu, Qiang; Zeng, Jun; Cheng, Tian

2018-01-01

Recommender systems are vulnerable to shilling attacks. Forged user-generated content data, such as user ratings and reviews, are used by attackers to manipulate recommendation rankings. Shilling attack detection in recommender systems is of great significance to maintain the fairness and sustainability of recommender systems. The current studies have problems in terms of the poor universality of algorithms, difficulty in selection of user profile attributes, and lack of an optimization mechanism. In this paper, a shilling behaviour detection structure based on abnormal group user findings and rating time series analysis is proposed. This paper adds to the current understanding in the field by studying the credibility evaluation model in-depth based on the rating prediction model to derive proximity-based predictions. A method for detecting suspicious ratings based on suspicious time windows and target item analysis is proposed. Suspicious rating time segments are determined by constructing a time series, and data streams of the rating items are examined and suspicious rating segments are checked. To analyse features of shilling attacks by a group user's credibility, an abnormal group user discovery method based on time series and time window is proposed. Standard testing datasets are used to verify the effect of the proposed method.

Transforming War Fighting through the Use of Service Based Architecture (SBA) Technology

DTIC Science & Technology

2006-05-04

near-real-time video & telemetry to users on network using standard web-based protocols – Provides web-based access to archived video files MTI...Target Tracks Service Capabilities – Disseminates near-real-time MTI and Target Tracks to users on network based on consumer specified geographic...filter IBS SIGINT Service Capabilities – Disseminates near-real-time IBS SIGINT data to users on network based on consumer specified geographic filter

Enhancing collaborative filtering by user interest expansion via personalized ranking.

PubMed

Liu, Qi; Chen, Enhong; Xiong, Hui; Ding, Chris H Q; Chen, Jian

2012-02-01

Recommender systems suggest a few items from many possible choices to the users by understanding their past behaviors. In these systems, the user behaviors are influenced by the hidden interests of the users. Learning to leverage the information about user interests is often critical for making better recommendations. However, existing collaborative-filtering-based recommender systems are usually focused on exploiting the information about the user's interaction with the systems; the information about latent user interests is largely underexplored. To that end, inspired by the topic models, in this paper, we propose a novel collaborative-filtering-based recommender system by user interest expansion via personalized ranking, named iExpand. The goal is to build an item-oriented model-based collaborative-filtering framework. The iExpand method introduces a three-layer, user-interests-item, representation scheme, which leads to more accurate ranking recommendation results with less computation cost and helps the understanding of the interactions among users, items, and user interests. Moreover, iExpand strategically deals with many issues that exist in traditional collaborative-filtering approaches, such as the overspecialization problem and the cold-start problem. Finally, we evaluate iExpand on three benchmark data sets, and experimental results show that iExpand can lead to better ranking performance than state-of-the-art methods with a significant margin.

Through a Freirean Lens: Professional Learning, Faith-Based Schooling and Liberatory Education

ERIC Educational Resources Information Center

Scott, John Trevitt; Armstrong, Ann Cheryl

2014-01-01

This paper draws on a broader qualitative study of professional learning in schools of the Peoples of the Book (Christians, Jews and Muslims) in post-colonial Australia, addressing the role that the growing number of Australian faith-based schools play in shaping a just and inclusive Australian society. By reviewing material in the public domain,…

How clustering dynamics influence lumber utilization patterns in the Amish-based furniture industry in Ohio

Treesearch

Matthew S. Bumgardner; Gary W. Graham; P. Charles Goebel; Robert L. Romig

2011-01-01

Preliminary studies have suggested that the Amish-based furniture and related products manufacturing cluster located in and around Holmes County, Ohio, uses sizeable quantities of hardwood lumber. The number of firms within the cluster has grown even as the broader domestic furniture manufacturing sector has contracted. The present study was undertaken in 2008 (spring/...

Challenges facing gap-based silviculture and possible solutions for mesic northern forests in North America

Treesearch

Christel C. Kern; Julia I. Burton; Patricia Raymond; Anthony W. D' Amato; William S. Keeton; Alex Royo; Michael B. Walters; Christopher R. Webster; John L. Willis

2017-01-01

Gap-based silvicultural systems were developed under the assumption that richness, and diversity of tree species and other biota positively respond to variation in size of harvest-created canopy gaps. However, varying gap size alone often does not meet diversity objectives and broader goals to address contemporary forest conditions. Recent research highlights the need...

The Development and Evaluation of a Parent Training Manual for Home Instruction.

ERIC Educational Resources Information Center

Yaman, Nancy; Hanson, Ralph A.

The development of a simple and effective means of training parents and other non-professionals in the use of a home-based instructional program is the concern of this paper. The home-based program is the SWRL Parent-Assisted Learning Program (PAL). PAL was created as an adjunct to a broader communication skills program, First Year Communication…

An Informal Review of Certain Contemporary Religious Uses of Television: A Report on a Sabbatical Study Project.

ERIC Educational Resources Information Center

Chambers, Curtis A.

This informal study of the religious uses of television, based on direct on-site discussions with religious television producers, was undertaken in order to provide a broader base of understanding of current developments in the field, and to assess the viability of a television broadcast ministry for the United Methodist Church. Discussions with…

The Role of Mechanized Services in the Provision of Information with Special Reference to the University Environment.

ERIC Educational Resources Information Center

Heim, Kathleen M.

The use, history, and role of machine-readable data base technology is discussed. First the development of data base technology is traced from its beginnings as a special resource for science and technology to its broader use in universities, with descriptions of some specific services. Next the current status of mechanized information services in…

School Health Connection Goes Electronic: Developing a Health Information Management System for New Orleans' School-Based Health Centers. Program Results Report

ERIC Educational Resources Information Center

Rastorfer, Darl

2011-01-01

From February 2008 through April 2011, School Health Connection, a program of the Louisiana Public Health Institute, developed an electronic health information management system for newly established school-based health centers in Greater New Orleans. School Health Connection was established as part of a broader effort to restore community health…

Impact of Active Teaching Methods Implemented on Therapeutic Chemistry Module: Performance and Impressions of First-Year Pharmacy Students

ERIC Educational Resources Information Center

Derfoufi, Sanae; Benmoussa, Adnane; El Harti, Jaouad; Ramli, Youssef; Taoufik, Jamal; Chaouir, Souad

2015-01-01

This study investigates the positive impact of the Case Method implemented during a 4- hours tutorial in "therapeutic chemistry module." We view the Case Method as one particular approach within the broader spectrum of problem based or inquiry based learning approaches. Sixty students were included in data analysis. A pre-test and…

Design of a Golf Swing Injury Detection and Evaluation open service platform with Ontology-oriented clustering case-based reasoning mechanism.

PubMed

Ku, Hao-Hsiang

2015-01-01

Nowadays, people can easily use a smartphone to get wanted information and requested services. Hence, this study designs and proposes a Golf Swing Injury Detection and Evaluation open service platform with Ontology-oritened clustering case-based reasoning mechanism, which is called GoSIDE, based on Arduino and Open Service Gateway initative (OSGi). GoSIDE is a three-tier architecture, which is composed of Mobile Users, Application Servers and a Cloud-based Digital Convergence Server. A mobile user is with a smartphone and Kinect sensors to detect the user's Golf swing actions and to interact with iDTV. An application server is with Intelligent Golf Swing Posture Analysis Model (iGoSPAM) to check a user's Golf swing actions and to alter this user when he is with error actions. Cloud-based Digital Convergence Server is with Ontology-oriented Clustering Case-based Reasoning (CBR) for Quality of Experiences (OCC4QoE), which is designed to provide QoE services by QoE-based Ontology strategies, rules and events for this user. Furthermore, GoSIDE will automatically trigger OCC4QoE and deliver popular rules for a new user. Experiment results illustrate that GoSIDE can provide appropriate detections for Golfers. Finally, GoSIDE can be a reference model for researchers and engineers.

The Electronic Patient Reported Outcome Tool: Testing Usability and Feasibility of a Mobile App and Portal to Support Care for Patients With Complex Chronic Disease and Disability in Primary Care Settings

PubMed Central

Gill, Ashlinder; Khan, Anum Irfan; Hans, Parminder Kaur; Kuluski, Kerry; Cott, Cheryl

2016-01-01

Background People experiencing complex chronic disease and disability (CCDD) face some of the greatest challenges of any patient population. Primary care providers find it difficult to manage multiple discordant conditions and symptoms and often complex social challenges experienced by these patients. The electronic Patient Reported Outcome (ePRO) tool is designed to overcome some of these challenges by supporting goal-oriented primary care delivery. Using the tool, patients and providers collaboratively develop health care goals on a portal linked to a mobile device to help patients and providers track progress between visits. Objectives This study tested the usability and feasibility of adopting the ePRO tool into a single interdisciplinary primary health care practice in Toronto, Canada. The Fit between Individuals, Fask, and Technology (FITT) framework was used to guide our assessment and explore whether the ePRO tool is: (1) feasible for adoption in interdisciplinary primary health care practices and (2) usable from both the patient and provider perspectives. This usability pilot is part of a broader user-centered design development strategy. Methods A 4-week pilot study was conducted in which patients and providers used the ePRO tool to develop health-related goals, which patients then monitored using a mobile device. Patients and providers collaboratively set goals using the system during an initial visit and had at least 1 follow-up visit at the end of the pilot to discuss progress. Focus groups and interviews were conducted with patients and providers to capture usability and feasibility measures. Data from the ePRO system were extracted to provide information regarding tool usage. Results Six providers and 11 patients participated in the study; 3 patients dropped out mainly owing to health issues. The remaining 8 patients completed 210 monitoring protocols, equal to over 1300 questions, with patients often answering questions daily. Providers and patients accessed the portal on an average of 10 and 1.5 times, respectively. Users found the system easy to use, some patients reporting that the tool helped in their ability to self-manage, catalyzed a sense of responsibility over their care, and improved patient-centered care delivery. Some providers found that the tool helped focus conversations on goal setting. However, the tool did not fit well with provider workflows, monitoring questions were not adequately tailored to individual patient needs, and daily reporting became tedious and time-consuming for patients. Conclusions Although our study suggests relatively low usability and feasibility of the ePRO tool, we are encouraged by the early impact on patient outcomes and generally positive responses from both user groups regarding the potential of the tool to improve care for patients with CCDD. As is consistent with our user-centered design development approach, we have modified the tool based on user feedback, and are now testing the redeveloped tool through an exploratory trial. PMID:27256035

Enabling User Preferences Through Data Exchange

DOT National Transportation Integrated Search

1997-08-01

This paper describes a process, via user- air traffic management (ATM) data : exchange, for enabling user preferences in an ATM-based system. User : preferences may be defined in terms of a four-dimensional (4D) user-preferred : trajectory, or a seri...

47 CFR 64.613 - Numbering directory for Internet-based TRS users.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the user's Internet Protocol (IP) address. For each record associated with an IP Relay user, the URI... a VRS user's geographically appropriate NANP telephone number, the URI shall contain the IP address of the user's device. For each record associated with an IP Relay user's geographically appropriate...