Mentoring in Schools: An Impact Study of Big Brothers Big Sisters School-Based Mentoring
ERIC Educational Resources Information Center
Herrera, Carla; Grossman, Jean Baldwin; Kauh, Tina J.; McMaken, Jennifer
2011-01-01
This random assignment impact study of Big Brothers Big Sisters School-Based Mentoring involved 1,139 9- to 16-year-old students in 10 cities nationwide. Youth were randomly assigned to either a treatment group (receiving mentoring) or a control group (receiving no mentoring) and were followed for 1.5 school years. At the end of the first school…
ERIC Educational Resources Information Center
Bridgeland, John M.; Moore, Laura A.
2010-01-01
American children represent a great untapped potential in our country. For many young people, choices are limited and the goal of a productive adulthood is a remote one. This report paints a picture of who these children are, shares their insights and reflections about the barriers they face, and offers ways forward for Big Brothers Big Sisters as…
ERIC Educational Resources Information Center
Herrera, Carla; Kauh, Tina J.; Cooney, Siobhan M.; Grossman, Jean Baldwin; McMaken, Jennifer
2008-01-01
High schools have recently become a popular source of mentors for school-based mentoring (SBM) programs. The high school Bigs program of Big Brothers Big Sisters of America, for example, currently involves close to 50,000 high-school-aged mentors across the country. While the use of these young mentors has several potential advantages, their age…
ERIC Educational Resources Information Center
Jucovy, Linda; Herrera, Carla
2009-01-01
This issue of "Public/Private Ventures (P/PV) In Brief" is based on "High School Students as Mentors," a report that examined the efficacy of high school mentors using data from P/PV's large-scale random assignment impact study of Big Brothers Big Sisters school-based mentoring programs. The brief presents an overview of the findings, which…
Moodie, Marjory L; Fisher, Jane
2009-01-30
The Big Brothers Big Sisters (BBBS) program matches vulnerable young people with a trained, supervised adult volunteer as mentor. The young people are typically seriously disadvantaged, with multiple psychosocial problems. Threshold analysis was undertaken to determine whether investment in the program was a worthwhile use of limited public funds. The potential cost savings were based on US estimates of life-time costs associated with high-risk youth who drop out-of-school and become adult criminals. The intervention was modelled for children aged 10-14 years residing in Melbourne in 2004. If the program serviced 2,208 of the most vulnerable young people, it would cost AUD 39.5 M. Assuming 50% were high-risk, the associated costs of their adult criminality would be AUD 3.3 billion. To break even, the program would need to avert high-risk behaviours in only 1.3% (14/1,104) of participants. This indicative evaluation suggests that the BBBS program represents excellent 'value for money'.
Paternity testing in case of brother-sister incest.
Macan, Marijana; Uvodić, Petra; Botica, Vladimir
2003-06-01
We performed a paternity test in a case of incest between brother and sister. DNA from blood samples of the alleged parents and their two children was obtained with Chelex DNA extraction method and quantified with Applied Biosystems QuantiBlot quantitation kit. Polymerase chain reaction (PCR) amplification of DNA samples was performed with AmpFlSTR SGM Plus PCR amplification kit and GenePrint PowerPlex PCR amplification kit. The amplified products were separated and detected by using the Perkin Elmer's ABI PRISM trade mark 310 Genetic Analyser. DNA and data analysis of 17 loci and Amelogenin confirmed the suspicion of brother-sister incest. Since both children had inherited all of the obligate alleles from the alleged father, we could confirm with certainty of 99.999999% that the oldest brother in the family was the biological father of both children. Calculated data showed that even in a case of brother-sister incest, paternity could be proved by the analysis of Amelogenin and 17 DNA loci.
Having a Brother or Sister with Down Syndrome: Perspectives from Siblings
Skotko, Brian G.; Levine, Susan P.; Goldstein, Richard
2012-01-01
This study asks brothers and sisters about their feelings and perceptions toward their sibling with Down syndrome. We analyzed valid and reliable surveys from 822 brothers and sisters whose families were on the mailing lists of six non-profit Down syndrome organizations around the country. More than 96% of brothers/sisters that responded to the survey indicated that they had affection toward their sibling with Down syndrome; and 94% of older siblings expressed feelings of pride. Less than 10% felt embarrassed, and less than 5% expressed a desire to trade their sibling in for another brother or sister without Down syndrome. Among older siblings, 88% felt that they were better people because of their siblings with Down syndrome, and more than 90% plan to remain involved in their sibling’s lives as they become adults. The vast majority of brothers and sisters describe their relationship with their sibling with Down syndrome as positive and enriching. PMID:21910244
20 CFR 410.215 - Duration of entitlement; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Duration of entitlement; parent, brother, or...; Duration of Entitlement; Filing of Claims and Evidence § 410.215 Duration of entitlement; parent, brother, or sister. (a) parent, brother, or sister is entitled to benefits beginning with the month all the...
20 CFR 725.222 - Conditions of entitlement; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Conditions of entitlement; parent, brother... Benefits) § 725.222 Conditions of entitlement; parent, brother, or sister. (a) An individual is eligible for benefits as a surviving parent, brother or sister if all of the following requirements are met: (1...
20 CFR 725.223 - Duration of entitlement; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Duration of entitlement; parent, brother, or... Benefits) § 725.223 Duration of entitlement; parent, brother, or sister. (a) A parent, sister, or brother....222 are met. (b) The last month for which such parent is entitled to benefits is the month in which...
20 CFR 725.225 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of dependency; parent, brother, or sister. 725.225 Section 725.225 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION... Benefits) § 725.225 Determination of dependency; parent, brother, or sister. An individual who is the miner...
20 CFR 725.225 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Determination of dependency; parent, brother, or sister. 725.225 Section 725.225 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS... Benefits) § 725.225 Determination of dependency; parent, brother, or sister. An individual who is the miner...
20 CFR 725.225 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Determination of dependency; parent, brother, or sister. 725.225 Section 725.225 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS... Benefits) § 725.225 Determination of dependency; parent, brother, or sister. An individual who is the miner...
20 CFR 725.225 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Determination of dependency; parent, brother, or sister. 725.225 Section 725.225 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS... Benefits) § 725.225 Determination of dependency; parent, brother, or sister. An individual who is the miner...
20 CFR 725.225 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Determination of dependency; parent, brother, or sister. 725.225 Section 725.225 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS... Benefits) § 725.225 Determination of dependency; parent, brother, or sister. An individual who is the miner...
20 CFR 725.224 - Determination of relationship; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of relationship; parent... Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner was...
Brother-sister incest: data from anonymous computer-assisted self interviews.
Stroebel, Sandra S; O'Keefe, Stephen L; Beard, Keith W; Kuo, Shih-Ya; Swindell, Samuel; Stroupe, Walter
2013-01-01
Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self interview. Forty were classified as victims of brother-sister incest, 19 were classified as victims of father-daughter incest, and 232 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The other 1,230 served as controls. The victims of brother-sister incest had significantly more problematic outcomes than controls on many measures (e.g., more likely than the controls to endorse feeling like damaged goods, thinking that they had suffered psychological injury, and having undergone psychological treatment for childhood sexual abuse). However, victims of brother-sister incest also had significantly less problematic outcomes than victims of father-daughter incest on some measures (e.g., significantly less likely than the father-daughter incest victims to endorse feeling like damaged goods, thinking that they had suffered psychological injury, and having undergone psychological treatment for childhood sexual abuse).
When Your Brother or Sister Has Cancer
Help when a brother or sister has cancer. Learn how families cope and find support when a sibling has cancer. Tips to help you talk with your friends, deal with stress, and take care of your mind and body are also shared.
20 CFR 410.214 - Conditions of entitlement; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Conditions of entitlement; parent, brother...; Duration of Entitlement; Filing of Claims and Evidence § 410.214 Conditions of entitlement; parent, brother, or sister. An individual is entitled to benefits if: (a) Such individual: (1) Is the parent, brother...
ERIC Educational Resources Information Center
Smieja, Linda L.; And Others
This annotated bibliography provides a comprehensive review of literature focusing on brothers and sisters of children with emotional disorders. Some material addressing brothers and sisters of children who have physical, mental, or developmental disabilities is also included. The bibliography lists approximately 80 references covering a 10-year…
Freud on Brothers and Sisters: A Neglected Topic
ERIC Educational Resources Information Center
Sherwin-White, Susan
2007-01-01
This paper explores Freud's developing thought on brothers and sisters, and their importance in his psychoanalytical writings and clinical work. Freud's work on sibling psychology has been seriously undervalued. This paper aims to give due recognition to Freud's work in this area. (Contains 1 note.)
20 CFR 410.380 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Determination of dependency; parent, brother... MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and Dependency § 410.380 Determination of dependency; parent, brother, or sister. An individual who is the miner's...
20 CFR 410.380 - Determination of dependency; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Determination of dependency; parent, brother... MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and Dependency § 410.380 Determination of dependency; parent, brother, or sister. An individual who is the miner's...
Lövgren, Malin; Jalmsell, Li; Eilegård Wallin, Alexandra; Steineck, Gunnar; Kreicbergs, Ulrika
2016-04-01
The aim of this study was to examine siblings' experiences of their brother's or sister's cancer death and if these experiences influenced levels of anxiety 2-9 years later. This nationwide survey was conducted in Sweden in 2009. All siblings who had a brother/sister who was diagnosed with cancer before the age of 17 years and who died before the age of 25 years during 2000-2007 were invited. Of those, 174 siblings participated (participation rate: 73%). Mixed data from the survey about the siblings' experiences of death were included as well as data from the Hospital Anxiety and Depression Scale. To examine the experiences, descriptive statistics and content analysis were used. Mann-Whitney U-test was conducted to investigate if the experiences influenced anxiety 2-9 years later. The siblings reported poor knowledge and experienced a lack of communication about their brother's/sister's death, for example, about the time frame, bodily changes near death, and about their own experiences. Siblings who reported that no one talked with them about what to expect when their brother/sister was going to die reported higher levels of anxiety 2-9 years after the loss. Seventy percent reported that they witnessed their brother/sister suffering in the last hours in life. Many of those who were not present during the illness period and at the time of death expressed regret. It is important to prepare siblings for their brother's/sister's illness and death as it may decrease anxiety and regrets later on. Copyright © 2015 John Wiley & Sons, Ltd.
Living with a Brother Who Has an Autism Spectrum Disorder: A Sister's Perspective
ERIC Educational Resources Information Center
Connell, Zara O.; Halloran, Maeve O.; Doody, Owen
2016-01-01
People with Autism Spectrum Disorder (ASD) are born into families and influence family functioning both positively and negatively. One of the most enduring relationships a person with ASD will have is their relationship with a brother or sister. Services for people with ASD should provide effective support to families, which include brothers,…
Adult Sibling Relationships with Brothers and Sisters with Severe Disabilities
ERIC Educational Resources Information Center
Rossetti, Zach; Hall, Sarah
2015-01-01
The purpose of this qualitative study was to examine perceptions of adult sibling relationships with a brother or sister with severe disabilities and the contexts affecting the relationships. Adult siblings without disabilities (N = 79) from 19 to 72 years of age completed an online survey with four open-ended questions about their relationship…
Brothers and Sisters of Adults with Mental Retardation: Gendered Nature of the Sibling Relationship.
ERIC Educational Resources Information Center
Orsmond, Gael I.; Seltzer, Marsha Mailick
2000-01-01
Differences and similarities between 245 brothers and sisters of adults with mental retardation in the sibling relationship were examined. Sisters scored higher in the caregiving, companionship, and positive affect aspects of the sibling relationship. Sibling involvement increased over time, but was dependent upon changes in maternal health.…
20 CFR 410.340 - Determination of relationship; parent, brother, or sister.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Determination of relationship; parent, brother, or sister. 410.340 Section 410.340 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and...
Brother-Sister Incest: Data from Anonymous Computer-Assisted Self Interviews
ERIC Educational Resources Information Center
Stroebel, Sandra S.; O'Keefe, Stephen L.; Beard, Keith W.; Kuo, Shih-Ya; Swindell, Samuel; Stroupe, Walter
2013-01-01
Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self interview. Forty were classified as victims of brother-sister incest, 19 were classified as victims of father-daughter incest, and 232 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The…
"Brothers and Sisters": A Novel Way to Teach Human Resources Management.
ERIC Educational Resources Information Center
Bumpus, Minnette
2000-01-01
The novel "Brothers and Sisters" by Bebe Moore Campbell was used in a management course to explore human resource management issues, concepts, and theories. The course included prereading and postreading surveys, lecture, book review, and examination. Most of the students (92%) felt the novel was an appropriate way to meet course…
García-Parra, Esmeralda; Ochoa-Díaz-López, Héctor; García-Miranda, Rosario; Moreno-Altamirano, Laura; Morales, Helda; Estrada-Lugo, Erin Ingrid Jane; Solís-Hernández, Roberto
2015-06-01
Mexico, in recent decades, has developed several programs to eradicate the problem of infant malnutrition <5 years, primarily among those living in rural and indigenous areas. However, there is insufficient evidence on these programs’ impact on child health and nutrition. To describe the nutritional changes of two generations of brothers and sisters living in rural communities of Chiapas and who are Oportunidades beneficiaries. Cross-sectional study. It was determined: underweight, stunting, wasting and overweight plus obesity. Older brothers and sisters were evaluated in 2002-2003, for 2010-2011 younger brothers and sisters were evaluated, both groups were <5 years of age at the time of data collection. Malnutrition, in its three types is a problem. 43.4% of brothers and sisters evaluated in 2010-2011 showed stunting, underweight prevalence declined from 18% to 13.2%, wasting (low weight for height) increased from 8.1% to 10.4%. Overweight and obesity increased significantly by 12 percentage points among brothers and sisters, from 24.8% in 2002-2003 to 36.8% in 2010-2011. Malnutrition among male children is lower than their brothers and sisters from the 2002-2003 generation (stunting p=<0.05), overweight and obesity was 10.9 percentage points higher than their brothers and sisters (26.4% to 37.3%). Children beneficiaries from Opportunities have not yet overcome chronic malnutrition problems. This study shows that there is not a clear impact in improving the nutritional status of the study population. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
Who is the Effective Volunteer: Characteristics of Successful Big Brothers.
ERIC Educational Resources Information Center
Thorelli, Irene M.; Appel, Victor H.
The demographic characteristics of the typical volunteer, taken from the personnel files of 208 current and previous volunteers of a Big Brothers agency, indicate the following profile. The modal Big Brother is usually Anglo-American, is a young adult aged 18 to 25, is a student or a full-time employed person, has some college education, lives in…
Yilmaz, Bulent; Vellanki, Priyathama; Ata, Baris; Yildiz, Bulent Okan
2018-02-01
To provide an evidence-based assessment of metabolic syndrome, hypertension, and hyperlipidemia in first-degree relatives of women with polycystic ovary syndrome (PCOS). Systematic review and meta-analysis. Not applicable. Mothers, fathers, sisters, and brothers of women with and without PCOS. An electronic-based search with the use of PubMed from 1960 to June 2015 and cross-checked references of relevant articles. Metabolic syndrome, hypertension and dyslipidemia, and surrogate markers, including systolic blood pressure (BP), diastolic BP, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. Fourteen of 3,346 studies were included in the meta-analysis. Prevalence of the following was significantly increased in relatives of women with PCOS: metabolic syndrome (risk ratio [RR] 1.78 [95% confidence interval 1.37, 2.30] in mothers, 1.43 [1.12, 1.81] in fathers, and 1.50 [1.12, 2.00] in sisters), hypertension (RR 1.93 [1.58, 2.35] in fathers, 2.92 [1.92, 4.45] in sisters), and dyslipidemia (RR 3.86 [2.54, 5.85] in brothers and 1.29 [1.11, 1.50] in fathers). Moreover, systolic BP (mothers, sisters, and brothers), total cholesterol (mothers and sisters), low-density lipoprotein cholesterol (sisters), and triglycerides (mothers and sisters) were significantly higher in first-degree relatives of PCOS probands than in controls. Our results show evidence of clustering for metabolic syndrome, hypertension, and dyslipidemia in mothers, fathers, sisters, and brothers of women with PCOS. PROSPERO 2016 CRD42016048557. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Osuchowska-Kościjańska, Anna; Charzyńska, Katarzyna; Chadzyńska, Małgorzata; Drozdzyńska, Anna; Kasperek-Zimowska, Beata; Bednarek, Agata; Sawicka, Maryla
2014-01-01
The aim of the present study was to investigate sense of coherence in healthy siblings of persons suffering from schizophrenia as well as their ways of coping in the relationship with ill brother or sister. 40 healthy brothers and sisters of persons with ICD- 10 diagnosis of F20 to F29 participated in the present study. Orientation to Life Scale (SOC- 29) was used to assess sense of coherence and Ways of Coping with Stress questionnaire (SRSS) was used to examine stress coping strategies. Mean global score of siblings of persons with schizophrenia was 111 points. Subjects used coping strategies focused on problem significantly more often than those focused on emotions. Therapeutic work with healthy siblings should focus on strengthening sense of personal competence, development of personal resources and different ways of coping with stress, investigation of emotions that healthy siblings experience in the relationship with ill brother or sister as well as supporting the process of accepting changes in the relationship with the ill sibling.
McHale, S M; Sloan, J; Simeonsson, R J
1986-12-01
The subjects were 90 children between 6 and 15 years of age, 30 with autistic, 30 with mentally retarded, and 30 with nonhandicapped brothers or sisters. The children were questioned about their sibling relationships in an open-ended interview, and, in the case of children with handicapped siblings, they also responded to questions about particular problems they faced in regard to their brothers or sisters. In addition, mothers filled out a behavior rating scale in which they described the positive and negative aspects of their children's behavior toward the sibling. In general, children and mothers rated the sibling relationships positively. Group comparisons indicated that children with autistic and mentally retarded siblings did not differ on any self-report measures. Children with nonhandicapped siblings reported that their family relations were slightly more cohesive but otherwise did not differ in terms of their self-reports from children with handicapped siblings. Mothers of nonhandicapped children, however, rated the sibling relationships more negatively than did mothers of handicapped children. Further analyses revealed that status variables (age, gender, family size) were not as highly correlated with the quality of sibling relationships with handicapped children as were specific problem areas (e.g., perceptions of parental favoritism, coping ability, concerns about the handicapped child's future).
Code of Federal Regulations, 2010 CFR
2010-04-01
... RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.40 When determinations of relationship are made for parent, grandchild... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When determinations of relationship are made...
ERIC Educational Resources Information Center
Kennedy, Denise E.; Kramer, Laurie
2008-01-01
We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With Sisters and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER…
ERIC Educational Resources Information Center
Madan-Swain, Avi; And Others
1993-01-01
Examined coping and family adaptation in siblings (n=32) of cancer patients, their ill brothers and sisters (n=19), and control group of nonclinical children (n=10) with healthy siblings. Gender and age of sibling, birth order, and number of siblings were examined. Found better adaptation in larger families and decreased family involvement among…
Birth order and ratio of brothers to sisters in Spanish transsexuals.
Gómez-Gil, Esther; Esteva, Isabel; Carrasco, Rocío; Almaraz, M Cruz; Pasaro, Eduardo; Salamero, Manel; Guillamon, Antonio
2011-06-01
Three Western studies have shown that male-to-female (MF) homosexual transsexuals tend to be born later than their siblings and to come from sibships with more brothers than sisters. The objective of this study was to determine whether these variables would be replicated in 530 MF and female-to-male (FM) Spanish transsexuals according to sexual orientation. The results showed that MF homosexual transsexuals had significantly more older brothers than the non-homosexual MF group. Compared with the expected rates in the general population, birth order was significantly higher in both MF (Slater's Index = 0.59; Fraternal Index = 0.61; Sororal Index = 0.58) and FM homosexual transsexuals (Slater's Index = 0.65; Fraternal Index = 0.68; Sororal Index = 0.67), and sibling sex ratio was significantly higher than expected in homosexual MF (sex ratio = 0.55) but not in homosexual FM transsexuals. No significant differences were found in the non-homosexual subgroups. The replication of the later birth order and sibling sex-ratio effect in MF homosexual transsexuals corroborates previous findings in a variety of groups from different cultures and may suggest a common mechanism underlying the etiology of transsexualism.
Shivers, Carolyn M; Dykens, Elisabeth M
2017-01-01
Siblings of brothers or sisters with intellectual and developmental disabilities (IDD) are important but understudied family members. As many previous studies have relied on parent report of sibling outcomes, the use of sibling self-report is an important addition to the research. This study assessed the feelings of adolescent siblings toward their brothers or sisters with and without IDD, as well as broader aspects of sibling empathy. Data were collected via a national, online survey from 97 parent-sibling pairs. Siblings of individuals with IDD reported higher levels of anxiety toward the target child than did siblings of typically developing individuals. Sibling feelings toward the target child were related to both parental and target child factors, but only among families of individuals with IDD.
Prolegomenon to the Study of "Brother" as a Male Family Role.
ERIC Educational Resources Information Center
Arkin, William
1979-01-01
Directs the reader to sibling gender relationships. Patterns of intimacy in brother-brother and brother-sister relationships are identified. Masculine gender role patterns were expressed more frequently than classic sibling rivalry. Sisters, not mothers, were discovered to be the primary socializing agent for some of men's intimate relationships…
Factor, Rhonda J; Rothblum, Esther D
2017-01-01
A U.S. national sample of 295 transgender adults (trans women, trans men, and genderqueer individuals) and their cisgender siblings completed the Bem Sex-Role Inventory about their siblings as well as themselves, which enabled a comparison between self-perceptions and sibling's perceptions of personality characteristics. Self-reported personality characteristics scored as feminine of trans women were not statistically different from those of their cisgender sisters, but they were significantly higher than self-reported femininity scores of trans men, genderqueer individuals, and cisgender brothers. Self-reported personality characteristics scored as masculine of trans men did not differ significantly from those of their cisgender brothers, but they were higher than those of trans women. Trans men and cisgender brothers were viewed by their siblings in a more sex-typed way than they rated themselves, whereas trans women and cisgender sisters were rated by their siblings in a less sex-typed way than they viewed themselves.
Changes in Siblings Over Time After the Death of a Brother or Sister From Cancer.
Akard, Terrah Foster; Skeens, Micah A; Fortney, Christine A; Dietrich, Mary S; Gilmer, Mary Jo; Vannatta, Kathryn; Barrera, Maru; Davies, Betty; Wray, Sarah; Gerhardt, Cynthia A
2018-02-27
Limited research has examined the impact of a child's death from cancer on siblings. Even less is known about how these siblings change over time. This study compared changes in siblings 1 (T1) and 2 (T2) years after the death of a brother or sister from cancer based on bereaved parent and sibling interviews. Participants across 3 institutions represented 27 families and included bereaved mothers (n = 21), fathers (n = 15), and siblings (n = 26) ranging from 8 to 17 years old. Participants completed semistructured interviews. Content analysis identified emerging themes and included frequency counts of participant responses. McNemar tests examined differences in the frequency of responses between T1 and T2 data. Participants reported similar types of changes in bereaved siblings at both time points, including changes in sibling relationships, life perspectives, their personal lives, and school performance. A new theme of "openness" emerged at T2. Frequencies of responses differed according to mother, father, or sibling informant. Overall, participants less frequently reported changes at T2 versus T1. Compared with findings in the first year, participants reported greater sibling maturity at follow-up. Overall changes in bereaved siblings continued over 2 years with less frequency over time, with the exception of increases in maturity and openness. Providers can educate parents regarding the impact of death of a brother or sister over time. Nurses can foster open communication in surviving grieving siblings and parents as potential protective factors in families going through their grief.
ERIC Educational Resources Information Center
Shivers, Carolyn M.; Dykens, Elisabeth M.
2017-01-01
Siblings of brothers or sisters with intellectual and developmental disabilities (IDD) are important but understudied family members. As many previous studies have relied on parent report of sibling outcomes, the use of sibling self-report is an important addition to the research. This study assessed the feelings of adolescent siblings toward…
Cyr, Mireille; Wright, John; McDuff, Pierre; Perron, Alain
2002-09-01
Three groups of girls who were sexually abused (by either brothers, fathers, or stepfathers) were compared. The purpose was to identify the differing characteristics of the abuse, the family environments, and the psychosocial distress of these children. Seventy-two girls aged between 5 and 16 were assigned to one of the three groups. Subjects were matched between groups on the basis of their actual age. Children completed measures of traumatic stress; their mothers completed the Child Behavior Checklist-Parent Report Form (CBCL) and other self-report questionnaires on family characteristics. Workers in child protective services completed information regarding the nature and severity of the abuse. Results suggested few differences in the characteristics of sexual abuse between the three groups. However, penetration was much more frequent in the sibling incest group (70.8%) than in the stepfather incest (27.3%) or father incest (34.8%) groups. Ninety percent of the victims of fathers and brothers manifested clinically-significant distress on at least one measure, whereas 63.6% of stepfather victims did. Compared with father and stepfather perpetrators, brothers were raised in families with more children and more alcohol abuse. The authors conclude that the characteristics of brother-sister incest and its associated psychosocial distress did not differ from the characteristics of father-daughter incest These findings suggest that theoretical models and clinical practices should be adjusted accordingly and that sibling incest should not necessarily be construed as less severe or harmful than father-daughter incest.
Benderix, Ylva; Sivberg, Bengt
2007-10-01
The aim of this study was to describe the present and past experiences of 14 siblings from five families in terms of having a brother or sister with autism and mental retardation. Personal interviews were conducted with the siblings before their brothers or sisters were moved to a newly opened group home. Qualitative content analysis was used for the analysis of the transcribed texts. The analysis resulted in seven content categories: precocious responsibility, feeling sorry, exposed to frightening behavior, empathetic feelings, hoping that a group home will be a relief, physical violence made siblings feel unsafe and anxious, and relations with friends were affected negatively. The conclusion is that these siblings' experiences revealed stressful life conditions. Counseling for the family and for siblings is recommended to help them deal with their feelings and problems. For the siblings in these five families, a group home was a relevant alternative as a temporary or permanent placement for the child with autism and mental retardation.
Incestuous Sisters: Mate Preference for Brothers over Unrelated Males in Drosophila melanogaster
Loyau, Adeline; Cornuau, Jérémie H.; Clobert, Jean; Danchin, Étienne
2012-01-01
The literature is full of examples of inbreeding avoidance, while recent mathematical models predict that inbreeding tolerance or even inbreeding preference should be expected under several realistic conditions like e.g. polygyny. We investigated male and female mate preferences with respect to relatedness in the fruit fly D. melanogaster. Experiments offered the choice between a first order relative (full-sibling or parent) and an unrelated individual with the same age and mating history. We found that females significantly preferred mating with their brothers, thus supporting inbreeding preference. Moreover, females did not avoid mating with their fathers, and males did not avoid mating with their sisters, thus supporting inbreeding tolerance. Our experiments therefore add empirical evidence for inbreeding preference, which strengthens the prediction that inbreeding tolerance and preference can evolve under specific circumstances through the positive effects on inclusive fitness. PMID:23251487
Incestuous sisters: mate preference for brothers over unrelated males in Drosophila melanogaster.
Loyau, Adeline; Cornuau, Jérémie H; Clobert, Jean; Danchin, Etienne
2012-01-01
The literature is full of examples of inbreeding avoidance, while recent mathematical models predict that inbreeding tolerance or even inbreeding preference should be expected under several realistic conditions like e.g. polygyny. We investigated male and female mate preferences with respect to relatedness in the fruit fly D. melanogaster. Experiments offered the choice between a first order relative (full-sibling or parent) and an unrelated individual with the same age and mating history. We found that females significantly preferred mating with their brothers, thus supporting inbreeding preference. Moreover, females did not avoid mating with their fathers, and males did not avoid mating with their sisters, thus supporting inbreeding tolerance. Our experiments therefore add empirical evidence for inbreeding preference, which strengthens the prediction that inbreeding tolerance and preference can evolve under specific circumstances through the positive effects on inclusive fitness.
Learning English through Social Interaction: The Case of "Big Brother 2006," Finland
ERIC Educational Resources Information Center
Kaanta, Leila; Jauni, Heidi; Leppanen, Sirpa; Peuronen, Saija; Paakkinen, Terhi
2013-01-01
In line with recent Conversation Analytic work on language learning as situated practice, this article investigates how interactants can create language learning opportunities for themselves and others in and through social interaction. The study shows how the participants of "Big Brother Finland," a reality TV show, whose main…
Psychological health in siblings who lost a brother or sister to cancer 2 to 9 years earlier.
Eilegård, Alexandra; Steineck, Gunnar; Nyberg, Tommy; Kreicbergs, Ulrika
2013-03-01
The objective of this study was to assess long-term psychological distress in siblings who lost a brother or sister to cancer 2 to 9 years earlier, as compared with a control group of non-bereaved siblings from the general population. During 2009, we conducted a nationwide follow-up study in Sweden by using an anonymous study-specific questionnaire. Siblings who had lost a brother or sister to cancer between the years 2000 and 2007 and also a control group of non-bereaved siblings from the general population were invited to participate. The Hospital Anxiety and Depression Scale (HADS) was used to measure psychological distress, and to test for differences in the ordinal outcome responses between the groups, we used Wilcoxon-Mann-Whitney rank-sum test. Among the bereaved siblings, 174/240 (73%) participated and 219/293 (75%) among the non-bereaved. Self-assessed low self-esteem (p = 0.002), difficulties falling asleep (p = 0.005), and low level of personal maturity (p = 0.007) at follow-up were more prevalent among bereaved siblings. However, anxiety (p = 0.298) and depression (p = 0.946), according to HADS, were similar. Bereaved siblings are at increased risk of low self-esteem, low level of personal maturity and difficulties falling asleep as compared with non-bereaved peers. Yet, the bereaved were not more likely to report anxiety or depression. Copyright © 2012 John Wiley & Sons, Ltd.
Sister-sister incest: data from an anonymous computerized survey.
Stroebel, Sandra S; O'Keefe, Stephen L; Griffee, Karen; Kuo, Shih-Ya; Beard, Keith W; Kommor, Martin J
2013-01-01
Retrospective data were entered anonymously by 1,521 adult women using a computer-assisted self-interview. Thirty-one participants were victims of sister-sister incest, 40 were victims of brother-sister incest, 19 were victims of father-daughter incest, 8 were victims of sexual abuse by an adult female (including one mother), and 232 were victims of sexual abuse by an adult male other than their father before reaching 18 years of age. The rest (1,203) served as controls. The victims of sister-sister incest had significantly more problematic outcomes than controls on many measures as adults. Victims of sister-sister incest were more depressed and more likely than controls to be distant from the perpetrator-sister and to have traded sex for money, experienced an unplanned pregnancy, engaged in four different types of masturbation, and engaged in 13 different same-sex behaviors. Our findings were consistent with other reports of early eroticization and persistent hypereroticization of incest victims.
Challenging stereotypes? The older woman in the TV series Brothers & Sisters.
Oró-Piqueras, Maricel
2014-12-01
The TV series, Brothers & Sisters, broadcast from 2006 to 2011 by ABC (USA) and a year later by Channel 4 (UK) with quite high audience rates, starts when the patriarchal figure, William Walker, dies of a heart attack and two female figures around their sixties come center stage: his wife, Nora Walker, and his long-term lover, Holly Harper. Once the patriarchal figure disappears, the female characters regain visibility by entering the labor market and starting relationships with other men. In that sense, both protagonists experience aging as a time in which they are increasingly freed from social and family constraints. However, their roles as nurturers keep on bringing them back to the domestic space in which they are safe from being involved in uncomfortable and unsuitable situations. Drawing on previous studies on the representation of the older woman in fictional media, this article intends to discern to what extent stereotypes related to the older woman are challenged through the two main protagonists of a contemporary TV series. Copyright © 2014 Elsevier Inc. All rights reserved.
The Role of Gender in Youth Mentoring Relationship Formation and Duration
ERIC Educational Resources Information Center
Rhodes, Jean; Lowe, Sarah R.; Litchfield, Leon; Walsh-Samp, Kathy
2008-01-01
The role of gender in shaping the course and quality of adult-youth mentoring relationships was examined. The study drew on data from a large, random assignment evaluation of Big Brothers Big Sisters of America (BBSA) programs [Grossman, J. B., & Tierney, J. P. (1998). Does mentoring work? An impact study of the Big Brothers Big Sisters program.…
Empowerment, Participation, and Democracy? -- The Hong Kong Big Sisters' Guidance Programme.
ERIC Educational Resources Information Center
Bottery, Mike; Siu, Shun-Mei
1996-01-01
Asserts that the Big Sisters Programme in Hong Kong provides a good example of a scheme that transcends personal and school issues and facilitates a more participative and democratic view of society. Characterizes the program as a benign form of a "hidden curriculum" and recommends establishing it in secondary schools. (MJP)
School-Based Mentoring: Big Brothers Big Sisters
ERIC Educational Resources Information Center
Henry, Leon
2009-01-01
Students attacking other students. Students attacking teachers, support staff, and even community members. Disrespectful and threatening language, overwhelmed or inattentive parents, and an administrative system that often appears unable to bring back order in the classroom. These are stories have become an everyday part of teaching in urban…
Cowpox virus infection in two brothers with possible human to human transmission.
Tamulyte, G; Lauraitis, J; Ganceviciene, R; Grigaitiene, J; Zouboulis, C C
2018-05-31
Two brothers from countryside were admitted to our centre with history of necrotic ulcers. Both of them were treated with oral and intravenous antibiotics, but treatment was ineffective. A 12-year-old boy had lesions on his head lasting for 4 weeks. Skin lesions started 1 week after he played with rats and neighbour's domestic calves, sheep and goats. Before the eruption occurred, the patient had subfebrile temperature and flu-like symptoms. Less severe eruption and symptoms were reported by his mother and 3-year-old sister. The 16-year-old boy had necrotic ulcers on the face. He had febrile temperature one week after his brother developed the eruption. The patient had close contact with his brother and sister but denied any contact with domestic or wild animals. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.
ERIC Educational Resources Information Center
Cyr, Mireille; Wright, John; McDuff, Pierre; Perron, Alain
2002-01-01
A study compared 72 girls (ages 5-16) sexually abused by brothers, fathers, or stepfathers. Results suggested few differences in characteristics of sexual abuse. However, penetration was much more frequent in the sibling incest group. More victims of fathers and brothers manifested clinically significant distress (90%), than stepfather victims…
Blanchard, Ray
2004-09-21
Meta-analysis of aggregate data from 14 samples representing 10,143 male subjects shows that homosexuality in human males is predicted by higher numbers of older brothers, but not by higher numbers of older sisters, younger brothers, or younger sisters. The relation between number of older brothers and sexual orientation holds only for males. This phenomenon has therefore been called the fraternal birth order effect. Research on birth order, birth weight, and sexual orientation suggests that the developmental pathway to homosexuality initiated by older brothers operates during prenatal life. Calculations assuming a causal relation between older brothers and sexual orientation have estimated the proportion of homosexual men who owe their sexual orientation to fraternal birth order at 15% in one study and 29% in another. The maternal immune hypothesis proposes that the fraternal birth order effect reflects the progressive immunization of some mothers to male-specific antigens by each succeeding male fetus and the increasing effects of such immunization on sexual differentiation of the brain in each succeeding male fetus. There are at least three possible mechanisms by which the mother's immune response could influence the fetus: the transfer of anti-male antibodies across the placenta from the maternal into the fetal compartment, the transfer of maternal cytokines across the placenta, and maternal immune reactions affecting the placenta itself. This hypothesis is consistent with recent studies showing that the quantity of fetal cells that enter the maternal circulation is greater than previously thought, and that the number of male-specific proteins encoded by Y-chromosome genes is greater than previously thought.
Familial Churg-Strauss Syndrome in a Sister and Brother.
Alyasin, Soheyla; Khoshkhui, Maryam; Amin, Reza
2015-06-01
Churg-Strauss syndrome (CSS) is a granulomatous small vessel vasculitis. It is characterized by asthma, allergic granulomatosis and vasculitis. This syndrome is rare in children. A 5 years old boy was admitted with cough, fever and dyspnea for 2 weeks. On the basis of laboratory data (peripheral eosinophilia), associated with skin biopsy, and history of CSS in his sister, this disease was eventually diagnosed. The patient had good response to corticosteroid. In every asthmatic patient with prolonged fever, eosinophilia and multisystemic involvment, CSS should be considered.
ERIC Educational Resources Information Center
Black, Susan
1999-01-01
Mentoring programs cannot always obliterate deficiencies in adult/child relationships or better student achievement. Two successful programs are the Big Brother/Big Sister program and the Office of Juvenile Justice's Juvenile Mentoring Program. (JUMP). Social support, not social control, is essential. Sidebars contain program tips and selected…
Nolbris, Margaretha Jenholt; Nilsson, Stefan
Siblings of a child with a life-threatening disease, such as cancer, have a right to measures that promote their health and welfare. Siblings may find it hard to understand what is happening to the sick child with cancer and why he or she reacts as he or she does. The aim of the study was to explore sibling supporters' thoughts about the experiences they had in providing support for siblings with a brother or a sister with a life-threatening disease such as cancer. All the 12 sibling supporters currently working in Sweden participated in a qualitative, descriptive study from which 5 categories emerged, showing that the sibling supporters supported siblings from diagnosis until possible death. They enabled siblings who were in the same situation to meet each other and arranged activities suited to their ages, as well as offering an encouraging environment. To help the siblings, the sibling supporters found it necessary to interact with both the parents and the ward staff. The sibling supporters felt that their support was important and necessary in helping siblings promote their own health both when the sick child was alive and also after his or her death. The experience of the sibling supporters was that they listened to the siblings' stories and met them when they were in their crisis. The study confirms that sibling supporters should be a part of the health care team that treat and support the family when a child has cancer.
ERIC Educational Resources Information Center
Gaddis, S. Michael
2012-01-01
After 25 years of intense scrutiny, social capital remains an important yet highly debated concept in social science research. This research uses data from youth and mentors in several chapters of Big Brothers/Big Sisters to assess the importance of different mentoring relationship characteristics in creating positive outcomes among youths. The…
High School Teen Mentoring Handbook
ERIC Educational Resources Information Center
Alberta Advanced Education and Technology, 2009
2009-01-01
Big Brothers Big Sisters Edmonton & Area, in partnership with Alberta Advanced Education and Technology, are providing the High School Teen Mentoring Program, a school-based mentoring program where mentor-mentee matches meet for one hour per week to engage in relationship-building activities at an elementary school. This initiative aims to…
ERIC Educational Resources Information Center
Bayer, Amanda; Grossman, Jean Baldwin; DuBois, David L.
2013-01-01
Previous research suggests that school-based mentoring programs like those offered by Big Brothers Big Sisters of America (BBBSA) yield small but statistically significant improvements in the academic performance of mentored students and in their beliefs in their own scholastic efficacy. The present study uses data from a randomized control trial…
ERIC Educational Resources Information Center
Chan, Christian S.; Rhodes, Jean E.; Howard, Waylon J.; Lowe, Sarah R.; Schwartz, Sarah E. O.; Herrera, Carla
2013-01-01
This study explores the pathways through which school-based mentoring relationships are associated with improvements in elementary and high school students' socio-emotional, academic, and behavioral outcomes. Participants in the study (N = 526) were part of a national evaluation of the Big Brothers Big Sisters school-based mentoring programs, all…
ERIC Educational Resources Information Center
Wheeler, Marc E.; Keller, Thomas E.; DuBois, David L.
2010-01-01
Between 2007 and 2009, reports were released on the results of three separate large-scale random assignment studies of the effectiveness of school-based mentoring programs for youth. The studies evaluated programs implemented by Big Brothers Big Sisters of America (BBBSA) affiliates (Herrera et al., 2007), Communities In Schools of San Antonio,…
ERIC Educational Resources Information Center
Brady, Bernadine; O'Regan, Connie
2009-01-01
The youth mentoring program Big Brothers Big Sisters is one of the first social interventions involving youth in Ireland to be evaluated using a randomized controlled trial methodology. This article sets out the design process undertaken, describing how the research team came to adopt a concurrent embedded mixed methods design as a means of…
ERIC Educational Resources Information Center
Spangenberg, Cynthia Pont
Results of a study involving 20 hard of hearing school aged students indicated that Ss in two experimental conditions (language stimulation by Big Brothers or Big Sisters and special training in oral and written language skills with a hearing specialist) increased in the complexity of their oral language more than control Ss did. (CL)
ERIC Educational Resources Information Center
Trammel, Ming
This research compendium summarizes and reviews the evaluations of 13 out-of-school time programs with positive outcomes for young people. The programs are (1) 4-H; (2) 21st Century Community Learning Centers; (3) The After-School Corporation; (4) Beacons; (5) BELL After School Instructional Curriculum; (6) Big Brothers Big Sisters of America; (7)…
Testicular cancer in two brothers of a quadruplet: a case report and a review of literature.
Ulytė, Agnė; Ulys, Albertas; Sužiedėlis, Kęstutis; Patašius, Aušvydas; Smailytė, Giedrė
2017-01-01
Introduction. Testicular cancer and a multiple birth are both rare events, and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister). Case description. Both patients were diagnosed at 21 years of age and died within two years from the diagnosis despite treatment. The third symptomless brother did not have testicular pathology. We also review the risk factors associated with testicular cancer, and the proposed hypotheses how a multiple birth results in an increased risk. The most consistent risk factors for testicular cancer are cryptorchidism, prior history of testicular cancer, and a positive familial history. According to different studies, the risk of testicular cancer in twins is higher from 22% to 30%, compared to the general population. Conclusions. To our knowledge, we have presented the first case of testicular teratoblastoma in brothers of a quadruplet.
Eliminating the Lost Time Interval of Law Enforcement to Active Shooter Events in Schools
2015-09-01
Bureau of Justice Assistance BJS Bureau of Justice Statistics BPD Blacksburg Police Department CPR cardiopulmonary resuscitation CSP...Big Brother and Big Sisters,11 and the Strengthening Families program.12 The Bureau of Justice Statistics (BJS) released the Indicators of School...result in school transfers or discipline were found to increase delinquency , dropout rate, and increased violence.44 Profiling students in an attempt
Big brothers and little sisters? Sex selection and birth order.
Salmon, Catherine
2007-09-01
Should you be allowed to choose the sex of your child? Even before the advent of modern reproductive technologies, people have expressed interest in producing a child of a specific sex, trying everything from herbal treatments to sexual positions that have been claimed to produce a male or female child. Modern technologies such as flow cytometry make this a realistic possibility but what might the consequences be? In India and China, a preference for male offspring has led (via abortion) to a significant sex-ratio imbalance in those populations. Do other countries express strong preferences for male or female offspring? This article will address the possible birth order implications. Will we live in a world of first-born boys and second-born girls?
ERIC Educational Resources Information Center
Forbes, Eric
1987-01-01
The younger brother of a hyperactive, severely learning-disabled 21-year-old recounts his feelings regarding lack of parental attention, jealousy toward his older brother, embarrassment, and finally empathy for his older brother. (CB)
32 CFR 1642.3 - Basis for classification in Class 3-A.
Code of Federal Regulations, 2014 CFR
2014-07-01
... because his child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon him for support; or (3) Whose deferment is advisable because his wife and child(ren), parent(s), grandparent(s..., child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon the registrant for...
32 CFR 1642.3 - Basis for classification in Class 3-A.
Code of Federal Regulations, 2010 CFR
2010-07-01
... because his child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon him for support; or (3) Whose deferment is advisable because his wife and child(ren), parent(s), grandparent(s..., child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon the registrant for...
32 CFR 1642.3 - Basis for classification in Class 3-A.
Code of Federal Regulations, 2013 CFR
2013-07-01
... because his child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon him for support; or (3) Whose deferment is advisable because his wife and child(ren), parent(s), grandparent(s..., child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon the registrant for...
32 CFR 1642.3 - Basis for classification in Class 3-A.
Code of Federal Regulations, 2012 CFR
2012-07-01
... because his child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon him for support; or (3) Whose deferment is advisable because his wife and child(ren), parent(s), grandparent(s..., child(ren), parent(s), grandparent(s), brother(s), or sister(s) is dependent upon the registrant for...
Sen. Toomey, Pat [R-PA
2014-12-11
Senate - 12/11/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:
ERIC Educational Resources Information Center
Tozer, Rosemary; Atkin, Karl; Wenham, Aniela
2014-01-01
Adult siblings of people with autism and a learning disability have hitherto been largely overlooked by research, policy and practice in the UK. As part of a qualitative study focussing on adult siblings, we met twelve people with autism plus severe learning disability with their brother or sister. Individually tailored resources were used to make…
Siblings of individuals with autism or Down syndrome: effects on adult lives.
Orsmond, G I; Seltzer, M M
2007-09-01
In this study, we examine instrumental and affective involvement in the sibling relationship for adults who have a brother or sister with an autism spectrum disorder (ASD) or Down syndrome (DS). We ask three research questions: (1) How do adult siblings of individuals with ASD differ from siblings of individuals with DS in their assessment of the quality of the sibling relationship and their experience of growing up with a brother or sister with a disability? (2) Are there gender effects on the sibling relationship and sibling experience in these two groups? (3) Which factors are predictive of variation in the sibling relationship for siblings of adults with ASD or DS? Data from 154 siblings who participated in two linked longitudinal studies were used. Seventy-seven siblings with a brother or sister with ASD were matched by age and gender to 77 siblings with a brother or sister with DS. The siblings in each group were between 21 and 56 years of age and over half were sisters. Siblings completed questionnaires on instrumental and affective involvement with their brother or sister with ASD or DS, the impact of growing up with a brother or sister with a disability on their lives, and their coping skills and feelings of pessimism. Compared with the siblings of adults with DS, siblings of adults with ASD had less contact with their brother or sister, reported lower levels of positive affect in the relationship, felt more pessimistic about their brother or sister's future, and were more likely to report that their relationships with their parents had been affected. For siblings of adults with ASD, a closer sibling relationship was observed when the sibling had lower educational levels, lived closer to the brother or sister with ASD, used more problem-focused coping strategies, and when his or her brother or sister with ASD had higher levels of functional independence. In contrast, for siblings of adults with DS, a closer sibling relationship was observed when the
7 CFR 6.23 - Eligibility to apply for a license.
Code of Federal Regulations, 2010 CFR
2010-01-01
... applicant if: (i) The applicant is the spouse, brother, sister, parent, child or grandchild of such other applicant; (ii) The applicant is the spouse, brother, sister, parent, child or grandchild of an individual..., brother, sister, parent, child or grandchild of an individual who owns or controls such other applicant...
50 CFR 622.18 - South Atlantic snapper-grouper limited access.
Code of Federal Regulations, 2011 CFR
2011-10-01
...: husband, wife, son, daughter, brother, sister, mother, or father; or (B) From an individual to a...: husband, wife, son, daughter, brother, sister, mother, or father. The application for transfer of a permit..., daughter, brother, sister, mother, or father. (iii) Except as provided in paragraphs (b)(1)(i) and (ii) of...
50 CFR 622.18 - South Atlantic snapper-grouper limited access.
Code of Federal Regulations, 2010 CFR
2010-10-01
...: husband, wife, son, daughter, brother, sister, mother, or father; or (B) From an individual to a...: husband, wife, son, daughter, brother, sister, mother, or father. The application for transfer of a permit..., daughter, brother, sister, mother, or father. (iii) Except as provided in paragraphs (b)(1)(i) and (ii) of...
Code of Federal Regulations, 2012 CFR
2012-07-01
...; followed by children, parents, brothers and sisters, etc. When the next of kin as defined by the laws of decedent's domicile consists of a number of persons as children, parents, brothers and sisters, etc..., consists of a number of persons such as children, parents, brothers and sisters, etc., permission to...
A brother and sister with breast cancer, BRCA2 mutations and bilateral supernumerary nipples
Coad, Ryan
2017-01-01
We describe a 54-year-old man with breast cancer and a BRCA2 mutation who was also found to have bilateral supernumerary nipples. His sister, also with a BRCA2 mutation, was diagnosed with breast cancer in her late forties; she also had bilateral supernumerary nipples. We address the significance of breast cancer arising in breast tissue underlying supernumerary nipples; the known association between supernumerary nipples and genitourinary malignancies/malformations and the possible link between BRCA2 and supernumerary nipple development. We believe that this is the first described case of the latter. We then outline an approach to further management for supernumerary nipple cases. PMID:28361071
26 CFR 1.2-2 - Definitions and special rules.
Code of Federal Regulations, 2011 CFR
2011-04-01
... mother, or an ancestor of either; (c) His stepfather or stepmother; (d) A son or a daughter of his brother or sister; (e) A brother or sister of his father or mother; or (f) His son-in-law, daughter-in-law, father-in-law, mother-in-law, brother- in-law, or sister-in-law; if such person has a gross income of...
26 CFR 1.2-2 - Definitions and special rules.
Code of Federal Regulations, 2010 CFR
2010-04-01
... mother, or an ancestor of either; (c) His stepfather or stepmother; (d) A son or a daughter of his brother or sister; (e) A brother or sister of his father or mother; or (f) His son-in-law, daughter-in-law, father-in-law, mother-in-law, brother- in-law, or sister-in-law; if such person has a gross income of...
Hodapp, R M; Urbano, R C
2007-12-01
As adults with Down syndrome live increasingly longer lives, their adult siblings will most likely assume caregiving responsibilities. Yet little is known about either the sibling relationship or the general functioning of these adult siblings. Using a national, web-based survey, this study compared adult siblings of individuals with Down syndrome to siblings of individuals with autism in terms of a potential 'Down syndrome advantage' and changes across age of the brother/sister with disabilities. Two groups were examined, siblings of persons with Down syndrome (n = 284) and with autism (n = 176). The Adult Sibling Questionnaire measured the number and length of contacts between siblings and their brothers/sisters with disabilities; the warmth, closeness and positiveness of the sibling relationship; and the sibling's overall levels of perceived health, depression and rewards of being a sibling. Compared with siblings of brothers/sisters with autism, siblings of brothers/sisters with Down syndrome showed closer, warmer sibling relationships, along with slightly better health, lower levels of depressive symptoms and more contacts. Across age groups of the brother/sister with disabilities, both groups showed lessened contacts, with less close sibling relationships occurring when brothers/sisters with disabilities were aged 30-44 years and 45 years and older (in Down syndrome) and 45 years and older (in autism). Within both groups, closer sibling relationships were associated with more frequent and lengthy contacts, brothers/sisters with disabilities who were better at maintaining friendships and had lower levels of behavioural/emotional problems, and siblings who felt themselves more rewarded by being a sibling to a brother/sister with disabilities. In line with earlier work on families of children with disabilities, this study shows an advantage for siblings of adults with Down syndrome, in terms of both sibling relationships and of slightly better health and
Paternity and inheritance of wealth
NASA Astrophysics Data System (ADS)
Hartung, John
1981-06-01
One of the oldest conjectures in anthropology is that men transfer wealth to their sister's son when the biological paternity of their `own' children is in doubt1-12. Because maternity is certain, a man is necessarily related to his sister's son and his brother (see Fig. 1). It is argued here that relatedness to male heirs can be assured by passing wealth to sister's sons or down a line of brothers, whether the prevailing kinship system reckons those brothers matrilineally or patrilineally. It is also argued that when several transfers of wealth are considered, a man's likelihood of being cuckolded need not be unrealistically high13 for his successive matrilineal heirs to be more related to him than his successive patrilineal heirs (see Fig. 2). Cross-cultural data on sister's son/brother inheritance14 and frequency of extramarital sex for females15 support the hypothesis that men tend to transmit wealth to their sister's son and/or brother when the probability that their putative children are their genetic children is relatively low.
Birth order in girls with gender identity disorder.
Zucker, K J; Lightbody, S; Pecore, K; Bradley, S J; Blanchard, R
1998-03-01
This study examined the birth order of girls with gender identity disorder (N = 22). Each proband was matched to 3-7 clinical control girls for age at assessment and number of siblings (the mode number of controls per proband was 7) (total N = 147). The number of older brothers, older sisters, younger brothers, and younger sisters was recorded. Slater's birth order index showed that the probands were significantly more likely to be early born than were the controls. A modified Slater's index also compared the birth order of the probands and the controls only to their brothers (when they had one or more) and only to their sisters (when they had one or more). Compared to the controls, the probands were born early compared to their sisters, but not to their brothers. These findings are the inverse of two previous studies of boys with gender identity disorder, who were later born relative to clinical control boys, an effect that appeared to be accounted for primarily by being born later relative to older brothers, but not to older sisters.
20 CFR 725.309 - Additional claims; effect of a prior denial of benefits.
Code of Federal Regulations, 2013 CFR
2013-04-01
... (child), and 725.222 (parent, brother, or sister)) has changed since the date upon which the order..., child, parent, brother, or sister shall be denied unless the applicable conditions of entitlement in...
20 CFR 725.309 - Additional claims; effect of a prior denial of benefits.
Code of Federal Regulations, 2011 CFR
2011-04-01
... (child), and 725.222 (parent, brother, or sister)) has changed since the date upon which the order..., child, parent, brother, or sister shall be denied unless the applicable conditions of entitlement in...
20 CFR 725.309 - Additional claims; effect of a prior denial of benefits.
Code of Federal Regulations, 2012 CFR
2012-04-01
... (child), and 725.222 (parent, brother, or sister)) has changed since the date upon which the order..., child, parent, brother, or sister shall be denied unless the applicable conditions of entitlement in...
20 CFR 725.309 - Additional claims; effect of a prior denial of benefits.
Code of Federal Regulations, 2010 CFR
2010-04-01
... (child), and 725.222 (parent, brother, or sister)) has changed since the date upon which the order..., child, parent, brother, or sister shall be denied unless the applicable conditions of entitlement in...
Code of Federal Regulations, 2010 CFR
2010-04-01
... family” means wife, husband, son, daughter, mother, father, brother, brother-in-law, sister, sister-in-law, son-in-law, daughter-in-law, mother-in-law, father-in-law, aunt, uncle, niece, nephew, stepparent...
Code of Federal Regulations, 2011 CFR
2011-04-01
... family” means wife, husband, son, daughter, mother, father, brother, brother-in-law, sister, sister-in-law, son-in-law, daughter-in-law, mother-in-law, father-in-law, aunt, uncle, niece, nephew, stepparent...
5 CFR 3201.106 - Employment of family members outside the Corporation.
Code of Federal Regulations, 2011 CFR
2011-01-01
... matter if the employer of the employee's spouse, child, parent, brother, sister, or a member of the... employment of the employee's spouse, child, parent, brother, sister, or a member of the employee's household...
5 CFR 3201.106 - Employment of family members outside the Corporation.
Code of Federal Regulations, 2012 CFR
2012-01-01
... matter if the employer of the employee's spouse, child, parent, brother, sister, or a member of the... employment of the employee's spouse, child, parent, brother, sister, or a member of the employee's household...
5 CFR 3201.106 - Employment of family members outside the Corporation.
Code of Federal Regulations, 2014 CFR
2014-01-01
... matter if the employer of the employee's spouse, child, parent, brother, sister, or a member of the... employment of the employee's spouse, child, parent, brother, sister, or a member of the employee's household...
5 CFR 3201.106 - Employment of family members outside the Corporation.
Code of Federal Regulations, 2013 CFR
2013-01-01
... matter if the employer of the employee's spouse, child, parent, brother, sister, or a member of the... employment of the employee's spouse, child, parent, brother, sister, or a member of the employee's household...
2013-01-14
Saturn small moons Atlas, Prometheus, and Epimetheus keep each other company in this image from NASA Cassini spacecraft of the planet night side. It seems fitting that they should do so since in Greek mythology, their namesakes were brothers.
10 CFR 1060.501 - Definitions.
Code of Federal Regulations, 2010 CFR
2010-01-01
..., by blood, marriage, or operation of law, as father, mother, son, daughter, brother, sister, uncle..., father-in-law, mother-in-law, son-in-law, daughter-in-law, brother-in-law, sister-in-law, stepfather...
10 CFR 1060.501 - Definitions.
Code of Federal Regulations, 2011 CFR
2011-01-01
..., by blood, marriage, or operation of law, as father, mother, son, daughter, brother, sister, uncle..., father-in-law, mother-in-law, son-in-law, daughter-in-law, brother-in-law, sister-in-law, stepfather...
32 CFR 1630.30 - Class 3-A: Registrant deferred because of hardship to dependents.
Code of Federal Regulations, 2011 CFR
2011-07-01
... upon him for support; or (2) Whose deferment is advisable because his child(ren), parent(s... advisable because his wife and his child(ren), parent(s), grandparent(s), brother(s), or sister(s) are...
32 CFR 1630.30 - Class 3-A: Registrant deferred because of hardship to dependents.
Code of Federal Regulations, 2012 CFR
2012-07-01
... upon him for support; or (2) Whose deferment is advisable because his child(ren), parent(s... advisable because his wife and his child(ren), parent(s), grandparent(s), brother(s), or sister(s) are...
32 CFR 1630.30 - Class 3-A: Registrant deferred because of hardship to dependents.
Code of Federal Regulations, 2014 CFR
2014-07-01
... upon him for support; or (2) Whose deferment is advisable because his child(ren), parent(s... advisable because his wife and his child(ren), parent(s), grandparent(s), brother(s), or sister(s) are...
32 CFR 1630.30 - Class 3-A: Registrant deferred because of hardship to dependents.
Code of Federal Regulations, 2013 CFR
2013-07-01
... upon him for support; or (2) Whose deferment is advisable because his child(ren), parent(s... advisable because his wife and his child(ren), parent(s), grandparent(s), brother(s), or sister(s) are...
32 CFR 1630.30 - Class 3-A: Registrant deferred because of hardship to dependents.
Code of Federal Regulations, 2010 CFR
2010-07-01
... upon him for support; or (2) Whose deferment is advisable because his child(ren), parent(s... advisable because his wife and his child(ren), parent(s), grandparent(s), brother(s), or sister(s) are...
Code of Federal Regulations, 2011 CFR
2011-07-01
...; followed by children, parents, brothers and sisters, etc. When the next of kin as defined by the laws of decedent's domicile consists of a number of persons as children, parents, brothers and sisters, etc...
20 CFR 725.309 - Additional claims; effect of prior denial of benefits.
Code of Federal Regulations, 2014 CFR
2014-04-01
... (see §§ 725.202(d) (miner), 725.212 (spouse), 725.218 (child), and 725.222 (parent, brother, or sister..., child, parent, brother, or sister must be denied unless the applicable conditions of entitlement in such...
The Sister Study will investigate the role of genetic, environmental, and lifestyle factors on the risk of breast cancer and other diseases in sisters of women with breast cancer. This research study will enroll 50,000 women who live in the United States and who are the cancer-fr...
Sisters and Brothers, Brothers and Sisters in the Family Affected by Traumatic Brain Injury.
ERIC Educational Resources Information Center
Pieper, Betty
This report is based on a qualitative research study which utilized a nominal group process to identify major life stressors for parents of children with traumatic brain injuries (TBI). It focuses first on effects of TBI on siblings and then on effective interventions. The first section uses quotes from participating parents to identify their…
12 CFR 225.41 - Transactions requiring prior notice.
Code of Federal Regulations, 2010 CFR
2010-01-01
... holding company whether or not pursuant to an express agreement. (3) Immediate family includes a person's father, mother, stepfather, stepmother, brother, sister, stepbrother, stepsister, son, daughter, stepson, stepdaughter, grandparent, grandson, granddaughter, father-in-law, mother-in-law, brother-in-law, sister-in-law...
Coyne, Sarah M; Jensen, Alexander C; Smith, Nathan J; Erickson, Daniel H
2016-02-01
Video games can be played in many different contexts. This study examined associations between coplaying video games between siblings and levels of affection and conflict in the relationship. Participants were 508 adolescents (M age = 16.31 years of age, SD = 1.08) who completed questionnaires on video game use and sibling relationships. Participants were recruited from a large Northwestern city and a moderate city in the Mountain West of the United States. Video games played between siblings were coded by an independent sample to assess levels of physical aggression and prosocial behavior in each game. Playing video games with a sibling was associated with higher levels of sibling affection for both boys and girls, but higher levels of conflict for boys only. Playing a violent video game with a brother was associated with lower levels of conflict in the sibling relationship, whereas playing a prosocial video game was not related to any sibling outcome. The value of video games in sibling relationships will be discussed, with a focus on the type of game and the sex of the adolescent. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.
Sibling rivalry and the gender gap: evidence from child health outcomes in Ghana.
Garg, A; Morduch, J
1998-01-01
"When capital and labor markets are imperfect, choice sets narrow, and parents must choose how to ration available funds and time between their children. One consequence is that children become rivals for household resources. In economies with pro-male bias, such rivalries can yield gains to having relatively more sisters than brothers. Using a rich household survey from Ghana [the 1988-1989 Ghana Living Standards Survey], we find that on average if children had all sisters (and no brothers) they would do roughly 25-40% better on measured health indicators than if they had all brothers (and no sisters)." excerpt
Novel insertion in exon 5 of the TCOF1 gene in twin sisters with Treacher Collins syndrome.
Marszałek-Kruk, Bożena Anna; Wójcicki, Piotr; Smigiel, Robert; Trzeciak, Wiesław H
2012-08-01
Treacher Collins syndrome (TCS) is associated with an abnormal differentiation of the first and second pharyngeal arches during fetal development. This causes mostly craniofacial deformities, which require numerous corrective surgeries. TCS is an autosomal dominant disorder and it occurs in the general population at a frequency of 1 in 50,000 live births. The syndrome is caused by mutations in the TCOF1 gene, which encodes the serine/alanine-rich protein named Treacle. Over 120 mutations of the TCOF1 gene responsible for TCS have been described. About 70% of recognized mutations are deletions, which lead to a frame shift, formation of a termination codon, and shortening of the protein product of the gene. Herewith, a new heterozygotic insertion, c.484_668ins185bp, was described in two monozygotic twin sisters suffering from TCS. This mutation was absent in their father, brother, and uncle, indicating a de novo origin. The insertion causes a shift in the reading frame and premature termination of translation at 167 aa. The novel insertion is the longest ever found in the TCOF1 gene and the only one found among monozygotic twin sisters.
38 CFR 1.10 - Eligibility for and disposition of the United States flag for burial purposes.
Code of Federal Regulations, 2010 CFR
2010-07-01
... separation from such service under conditions other than dishonorable, on or after April 25, 1951. (Authority... issued a flag on application signed by guardian). (iii) Parents, including adoptive, stepparents, and foster parents. (iv) Brothers or sisters, including brothers or sisters of the halfblood. (v) Uncles or...
Lövgren, Malin; Sveen, Josefin; Nyberg, Tommy; Eilegård Wallin, Alexandra; Prigerson, Holly G; Steineck, Gunnar; Kreicbergs, Ulrika
2018-02-01
A majority of cancer-bereaved siblings report long-term unresolved grief, thus it is important to identify factors that may contribute to resolving their grief. To identify modifiable or avoidable family and care-related factors associated with unresolved grief among siblings two to nine years post loss. This is a nationwide Swedish postal survey. Study-specific questions and the standardized instrument Hospital Anxiety and Depression Scale. Primary outcome was unresolved grief, and family and care-related factors were used as predictors. Cancer-bereaved sibling (N = 174) who lost a brother/sister to childhood cancer during 2000-2007 in Sweden (participation rate 73%). Seventy-three were males and 101 females. The age of the siblings at time of loss was 12-25 years and at the time of the survey between 19 and 33 years. Several predictors for unresolved grief were identified: siblings' perception that it was not a peaceful death [odds ratio (OR): 9.86, 95% confidence interval (CI): 2.39-40.65], limited information given to siblings the last month of life (OR: 5.96, 95% CI: 1.87-13.68), information about the impending death communicated the day before it occurred (OR: 2.73, 95% CI: 1.02-7.33), siblings' avoidance of the doctors (OR: 3.22, 95% CI: 0.75-13.76), and lack of communication with family (OR: 2.86, 95% CI: 1.01-8.04) and people outside the family about death (OR: 5.07, 95% CI: 1.64-15.70). Depressive symptoms (OR: 1.27, 95% CI: 1.12-1.45) and time since loss (two to four years: OR: 10.36, 95% CI: 2.87-37.48 and five to seven years: OR: 8.36, 95% CI: 2.36-29.57) also predicted unresolved grief. Together, these predictors explained 54% of the variance of unresolved grief. Siblings' perception that it was not a peaceful death and poor communication with family, friends, and healthcare increased the risk for unresolved grief among the siblings.
Brothers & Sisters Talk with PACER.
ERIC Educational Resources Information Center
Binkard, Betty; And Others
This booklet presents excerpts from interviews with siblings (ages 10-28) of persons with a range of handicaps, including Down Syndrome, cerebral palsy, learning disabilities, deafness, autism, seizure disorder, genetic disorders, and mental retardation. It is arranged in order from the youngest person interviewed and continues through…
Nature vs. nurture: two brothers with schizophrenia.
Keltner, N L; James, C A; Darling, R J; Findley, L S; Oliver, K
2001-01-01
The nature vs. nurture argument as it pertains to two brothers. To explore the synergistic effects of heritability and environment in the cases of two brothers with schizophrenia. Review of the literature and the authors' clinical experience. The nature vs. nurture dichotomy may not be as relevant as looking at the interaction between these two forces.
Code of Federal Regulations, 2010 CFR
2010-07-01
... preference among such persons. Usually the spouse is first entitled, except in some situations of separation; followed by children, parents, brothers and sisters, etc. When the next of kin as defined by the laws of decedent's domicile consists of a number of persons as children, parents, brothers and sisters, etc...
Blanchard, Ray
2014-07-01
The term "fraternal birth order effect" denotes a statistical relation most commonly expressed in one of two ways: Older brothers increase the odds of homosexuality in later born males or, alternatively, homosexual men tend to have more older brothers than do heterosexual men. The demonstrability of this effect depends partly on the adequate matching of the homosexual and heterosexual study groups with respect to mean family size. If the homosexual group has too many siblings, relative to the heterosexual group, the homosexual group will tend to show the expected excess of older brothers but may also show an excess of other sibling-types (most likely older sisters); if the homosexual group has too few siblings, it will tend not to show a difference in number of older brothers but instead may show a deficiency of other sibling-types (most likely younger brothers and younger sisters). In the first part of this article, these consequences are illustrated with deliberately mismatched groups selected from archived data sets. In the second part, two slightly different methods for transforming raw sibling data are presented. These are intended to produce family-size-corrected variables for each of the four original sibling parameters (older brothers, older sisters, younger brothers, and younger sisters). Both versions are shown to render the fraternal birth order effect observable in the deliberately mismatched groups. In the third part of the article, fraternal birth order studies published in the last 5 years were surveyed for failures to find a statistically significant excess of older brothers for the homosexual group. Two such studies were found in the nine examined. In both cases, the collective findings for older sisters, younger brothers, and younger sisters suggested that the mean family size of the homosexual groups was smaller than that of the heterosexual comparison groups. Furthermore, the individual findings for the four classes of siblings resembled those
20 CFR 410.200 - Types of benefits; general.
Code of Federal Regulations, 2010 CFR
2010-04-01
... entitlement to benefits for a miner, a widow, child, parent, brother, or sister; describe the events which... dependency requirements applicable to claimants for benefits as a widow, child, parent, brother, or sister... to pneumoconiosis; or (2) To the widow or child of a miner who was entitled to benefits at the time...
20 CFR 410.200 - Types of benefits; general.
Code of Federal Regulations, 2011 CFR
2011-04-01
... entitlement to benefits for a miner, a widow, child, parent, brother, or sister; describe the events which... dependency requirements applicable to claimants for benefits as a widow, child, parent, brother, or sister... to pneumoconiosis; or (2) To the widow or child of a miner who was entitled to benefits at the time...
Birth order and fluctuating asymmetry: a first look.
Lalumière, M L; Harris, G T; Rice, M E
1999-01-01
We investigated the hypothesis that maternal immunoreactivity to male-specific features of the foetus can increase developmental instability. We predicted that the participants' number of older brothers would be positively related to the fluctuating asymmetry of ten bilateral morphological traits. The participants were 40 adult male psychiatric patients and 31 adult male hospital employees. Consistent with the hypothesis, the participants' number of older brothers--but not number of older sisters, younger brothers or younger sisters--was positively associated with fluctuating asymmetry. The patients had significantly larger fluctuating asymmetry scores and tended to have more older brothers than the employees, but the positive relationship between the number of older brothers and fluctuating asymmetry was observed in both groups. PMID:10643079
ERIC Educational Resources Information Center
Orsmond, Gael I.; Seltzer, Marsha Mailick
2009-01-01
The purpose of this study was to test a diathesis-stress model of well-being for siblings who have a brother or sister with an autism spectrum disorder (ASD). Data were collected from 57 adolescents and their mothers. Sisters reported higher levels of depressive and anxiety symptoms than brothers. Having a family history of ASDs was associated…
Extreme right-handedness, older brothers, and sexual orientation in men.
Bogaert, Anthony F
2007-01-01
Two of the most consistent correlates of sexual orientation in men are handedness and fraternal birth order (i.e., number of older brothers). In the present study, the relationship among handedness, older brothers, and sexual orientation was studied in 4 samples of heterosexual and gay or bisexual men (N = 944). Unlike previous studies, which have only observed an increased rate of non-right-handedness in gay or bisexual men relative to heterosexual men, an elevated rate of extreme right-handedness was found in gay or bisexual men relative to heterosexual men. The results also demonstrated that older brothers moderate the relationship between handedness and sexual orientation. Specifically, older brothers increase the odds of being gay or bisexual in moderate right-handers only; in both non-right-handers and extreme right-handers, older brothers do not affect (or decrease) the odds of being gay or bisexual. The results have implications for an early neurodevelopmental origin to sexual orientation in men. (c) 2007 APA, all rights reserved.
VanderLaan, Doug P; Vasey, Paul L
2011-06-01
In Western cultures, male androphiles tend to have greater numbers of older brothers than male gynephiles (i.e., the fraternal birth order effect). In the non-Western nation of Independent Samoa, androphilic males (known locally as fa'afafine) have been shown to have greater numbers of older brothers, older sisters, and younger brothers (Vasey & VanderLaan, 2007). It is unclear, however, whether the observed older brother effect, in the context of the additional sibling category effects, represented a genuine fraternal birth order effect or was simply associated with elevated maternal fecundity. To differentiate between these two possibilities, this study employed a larger, independent replication sample of fa'afafine and gynephilic males from Independent Samoa. Fa'afafine had greater numbers of older brothers and sisters. The replication sample and the sample from Vasey and VanderLaan were then combined, facilitating a comparison that showed the older brother effect was significantly greater in magnitude than the older sister effect. These results suggest that fraternal birth order and maternal fecundity effects both exist in Samoa. The existence of these effects cross-culturally is discussed in the context of biological theories for the development of male androphilia.
Authentic Expression of Edmund Rice Christian Brother Education
ERIC Educational Resources Information Center
Vercruysse, Raymond J.
2007-01-01
In 1802, Edmund Rice directed the laying of the foundation stone for Mount Sion Monastery and School. After several previous attempts of instructing poor boys in Waterford, this was to be the first permanent home for the Congregation of Christian Brothers. Rice's dream of founding a religious community of brothers was becoming a reality with a…
East, P L; Shi, C R
1997-04-01
On the basis of social modeling theory and a sibling interaction hypothesis, it was hypothesized that specific relationship qualities between a pregnant or parenting teen and her younger sister would be associated with permissive younger sister outcomes, such as permissive childbearing attitudes and permissive sexual behavior. Results indicated that negative relationship qualities, such as rivalry, competition, and conflict, were more closely related to younger sisters engaging in problem delinquent-like behavior and sexual behavior than were positive relationship qualities, such as warmth and closeness. Additionally, a shared friendship network with the older sister was found to be associated with extensive younger sister problem behavior and sexual behavior. Three potential explanatory processes are discussed.
20 CFR 410.231 - Time limits for filing claims.
Code of Federal Regulations, 2011 CFR
2011-04-01
... of the widow, child, parent, brother, or sister of a miner must be filed by December 31, 1973, or... claim for benefits by or on behalf of the widow, child, parent, brother, or sister of a miner must be... claim by or on behalf of a surviving child of a miner or of such widow, must be filed within 6 months...
20 CFR 410.231 - Time limits for filing claims.
Code of Federal Regulations, 2010 CFR
2010-04-01
... of the widow, child, parent, brother, or sister of a miner must be filed by December 31, 1973, or... claim for benefits by or on behalf of the widow, child, parent, brother, or sister of a miner must be... claim by or on behalf of a surviving child of a miner or of such widow, must be filed within 6 months...
[The sibling status effects and the personality scales of the MMPI].
Hama, H; Mine, H; Mine, H; Matsuyama, Y
1987-06-01
The purpose of this study is to find out if the personalities of siblings are similar or different. Subjects used were Doshisha University students and members of their families, provided those families had only two children. Altogether 29 pairs of boys and their younger brothers, 47 pairs of boys and their younger sisters, 44 pairs of girls and their younger brothers, and 51 pairs of girls and their younger sisters were given the MMPI individually. Sibling status effects were found in many of the MMPI scores according to the type of sibling dyads and birth order, especially for the sibling dyad of elder brother and younger sister. Personality relationships between the first and second child showed that there were significant correlations in many MMPI scales: L, K, Pd, Pa, Pt, Sc, Si, Conflict resolution, Manifest anxiety, Repression-Sensitization, and Hostility. Among the four types of sibling dyad, the pairs of girls and their younger brothers showed the highest correlation in their personality.
The Mayo brothers: an American surgical legacy.
Toledo-Pereyra, Luis H
2010-10-01
Few in the history of surgery and just as few in the history of medicine can reach the level of clinical visibility as achieved by the Mayo brothers. The brothers changed the face of medicine while they were alive, and their fame and influence continued to grow after their death in 1939. The Mayo American surgical legacy had incredible proportions. The brothers systematically modified the field as few others had done before. They were great surgical innovators who took the surgical techniques of others and added a touch of their own to make the surgical procedure better and more secure. The Mayos were the stars regionally, nationally, and around the world. They attracted attention from their generation and occupied center stage long after. To speak of the Mayos is to speak of the quintessential American values of professionalism, respect, commitment, and caring for their fellow human beings. Their creation, the Mayo Clinic, surpassed the wildest hopes and predictions that anyone could have had regarding their best dreams.
75 FR 46864 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-04
...-0225; Directorate Identifier 2009-NM-203-AD] RIN 2120-AA64 Airworthiness Directives; Short Brothers PLC... this proposed AD, contact Short Brothers PLC, Airworthiness, P.O. Box 241, Airport Road, Belfast, BT3... Brothers PLC: Docket No. FAA-2010-0225; Directorate Identifier 2009-NM-203-AD. Comments Due Date (a) We...
Canturk, Kemal Murat; Emre, Ramazan; Gurkan, Cemal; Komur, Ilhami; Muslumanoglu, Omer; Dogan, Muhammed
2016-07-01
Here, we report an incest paternity case involving three biological brothers as alleged fathers (AFs), their biological sister and her child that was investigated using the Investigator ESSplex Plus, AmpFLSTR Identifiler Plus/Investigator IDplex Plus and PowerPlex 16 kits. Initial duo paternity investigations using 15-loci autosomal short tandem repeat (STR) analyses failed to exclude any of the AFs. Despite the fact that one of the brothers, AF1, had a mismatch with the child at a single locus (D2S1338), the possibility of a single-step mutation could not be ruled out. When the number of autosomal STR loci analysed was increased to 22 without the inclusion of the mother, AF2 and AF3 still could not be excluded, since both of them again had no mismatches with the child. A breakthrough was possible only upon inclusion of the mother so that trio paternity investigations were carried out. This time AF1 and AF2 could be excluded at two loci (D2S1338 and D1S1656) and six loci (vWa, D1S1656, D12S391, FGA, PENTA E and PENTA D), respectively, and AF3 was then the only brother who could not be excluded from paternity. Subsequent statistical analyses suggested that AF3 could be the biological father of the child with a combined paternity index >100 billion and a probability of paternity >99.99999999%. These findings consolidate the fact that complex paternity cases such as those involving incest could benefit more from the inclusion of the mother than simply increasing the number of STR loci analysed. © The Author(s) 2015.
Birth order and avuncular tendencies in Samoan men and fa'afafine.
Vanderlaan, Doug P; Vasey, Paul L
2013-04-01
Androphilia refers to sexual attraction and arousal to males whereas gynephilia refers to sexual attraction and arousal to females. In Samoa, transgendered androphilic males are known locally as fa'afafine. Previous research has shown that, compared to Samoan gynephilic men, fa'afafine report greater willingness to invest time and money toward nieces and nephews (i.e., greater avuncular tendencies) and also have greater numbers of older brothers and older sisters. The present study examined whether the Samoan male sexual orientation difference in avuncular tendencies could be accounted for by these parallel differences in numbers of older brothers and older sisters. The sample included 204 fa'afafine and 272 Samoan gynephilic men from our Samoan data archive for whom we had concurrent information on (1) a measure of willingness to invest time and money in nieces and nephews (i.e., avuncular tendencies) and (2) numbers of older and younger biological brothers and sisters. Among fa'afafine, but not Samoan gynephilic men, number of older brothers and number of older sisters were both significantly positively associated with avuncular tendencies. When controlling for number of older brothers, the magnitude of the male sexual orientation difference in avuncular tendencies was lowered, but remained statistically significant. In contrast, when controlling for number of older sisters, the male sexual orientation difference in avuncular tendencies ceased to exist. Discussion detailed how these findings help hone in on the proximate basis of elevated avuncular tendencies among fa'afafine. In addition, discussion focused on how particular evolutionary and cultural factors might relate to the avuncularity of fa'afafine.
76 FR 1985 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-12
... Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes AGENCY: Federal Aviation Administration (FAA..., June 16, 2006) and adding the following new AD: 2010-24-06 Short Brothers PLC: Amendment 39-16525..., Amendment 39-14644. Applicability (c) This AD applies to all Short Brothers PLC Model SD3-60 SHERPA, SD3...
75 FR 12154 - Airworthiness Directives; Short Brothers PLC Model SD3 Airplanes
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
...-0225; Directorate Identifier 2009-NM-203-AD] RIN 2120-AA64 Airworthiness Directives; Short Brothers PLC... Brothers PLC, Airworthiness, P.O. Box 241, Airport Road, Belfast, BT3 9DZ Northern Ireland; telephone +44(0... 34801, June 16, 2006) and adding the following new AD: Short Brothers PLC: Docket No. FAA-2010-0225...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-23
... Entertainment, Inc., Warner Brothers Theatrical Enterprises, Including Workers of the Following Operating..., Burbank, CA; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In... Labor issued a Certification of Eligibility to Apply for Worker Adjustment Assistance on September 24...
THREE SISTERS WILDERNESS, OREGON.
MacLeod, Norman S.; Causey, J. Douglas
1984-01-01
A mineral survey of the Three Sisters Wilderness, Oregon indicated little promise for the occcurrence of metallic mineral resources. Block pumice suitable for commercial uses occurs at an undeveloped claim at Rock Mesa in the wilderness, but numerous other sources occur outside the wilderness closer to markets. A broad area centered around South Sister volcano is among the most favorable targets for geothermal resources in the Oregon Cascade Range, based on the very young age and large volume of silicic volcanic rocks that occur in this area. Deep exploration holes could be drilled in areas outside the wilderness south of South Sister to provide data on the subsurface thermal and hydrologic regimes in the southern part of the area most likely to contain geothermal resources.
Biological versus nonbiological older brothers and men's sexual orientation.
Bogaert, Anthony F
2006-07-11
The most consistent biodemographic correlate of sexual orientation in men is the number of older brothers (fraternal birth order). The mechanism underlying this effect remains unknown. In this article, I provide a direct test pitting prenatal against postnatal (e.g., social/rearing) mechanisms. Four samples of homosexual and heterosexual men (total n = 944), including one sample of men raised in nonbiological and blended families (e.g., raised with half- or step-siblings or as adoptees) were studied. Only biological older brothers, and not any other sibling characteristic, including nonbiological older brothers, predicted men's sexual orientation, regardless of the amount of time reared with these siblings. These results strongly suggest a prenatal origin to the fraternal birth-order effect.
Currie, Janet
2013-04-01
Discussions of "big data" in medicine often revolve around gene sequencing and biosamples. It is perhaps less recognized that administrative data in the form of vital records, hospital discharge abstracts, insurance claims, and other routinely collected data also offer the potential for using information from hundreds of thousands, if not millions, of people to answer important questions. However, the increasing ease with which such data may be used and reused has increased concerns about privacy and informed consent. Addressing these concerns without creating insurmountable barriers to the use of such data for research is essential if we are to avoid a "missed opportunity" in pediatrics research.
Mixed pineal mature teratoma and germinoma in two brothers of the fraternal triplets.
Grahovac, Gordan; Alden, Tord; Nitin, Wadhwani
2017-05-01
Intracranial teratomas are rare germ cell neoplasms that contain tissues derived from all three germ cell layers and most commonly occurring during childhood. This is the first report of pineal region mixed mature teratoma and germinoma in two fraternal brothers of fraternal triplets. We report the case of a mixed mature teratoma and germinoma of the pineal region in two brothers of fraternal triplets. Older brother was initially diagnosed at the age of 11 years with the pure teratoma of the pineal region but the review of the pathology 3 years after initial surgery revealed the mixed mature teratoma with 5% germinomatous component. The younger brother was diagnosed at the age of 13 years with the mixed mature teratoma with 10% germinomatous component tumor of the pineal region. Younger brother has been treated with adjuvant chemo-radiotherapy and older brother was treated without adjuvant therapy. Both brothers had no recurrence. Pineal mature teratomas have a good prognosis, in contrast to their immature or mixed counterparts. A rigorous histological examination of the tumor samples is mandatory, in order to not omit a mixed contingent within the tumor.
Wall-Wieler, Elizabeth; Roos, Leslie L; Nickel, Nathan C
2016-05-25
Risk factors for teenage pregnancy are linked to many factors, including a family history of teenage pregnancy. This research examines whether a mother's teenage childbearing or an older sister's teenage pregnancy more strongly predicts teenage pregnancy. This study used linkable administrative databases housed at the Manitoba Centre for Health Policy (MCHP). The original cohort consisted of 17,115 women born in Manitoba between April 1, 1979 and March 31, 1994, who stayed in the province until at least their 20(th) birthday, had at least one older sister, and had no missing values on key variables. Propensity score matching (1:2) was used to create balanced cohorts for two conditional logistic regression models; one examining the impact of an older sister's teenage pregnancy and the other analyzing the effect of the mother's teenage childbearing. The adjusted odds of becoming pregnant between ages 14 and 19 for teens with at least one older sister having a teenage pregnancy were 3.38 (99 % CI 2.77-4.13) times higher than for women whose older sister(s) did not have a teenage pregnancy. Teenage daughters of mothers who had their first child before age 20 had 1.57 (99 % CI 1.30-1.89) times higher odds of pregnancy than those whose mothers had their first child after age 19. Educational achievement was adjusted for in a sub-population examining the odds of pregnancy between ages 16 and 19. After this adjustment, the odds of teenage pregnancy for teens with at least one older sister who had a teenage pregnancy were reduced to 2.48 (99 % CI 2.01-3.06) and the odds of pregnancy for teen daughters of teenage mothers were reduced to 1.39 (99 % CI 1.15-1.68). Although both were significant, the relationship between an older sister's teenage pregnancy and a younger sister's teenage pregnancy is much stronger than that between a mother's teenage childbearing and a younger daughter's teenage pregnancy. This study contributes to understanding of the broader topic "who is
Sister R. Leadership: Doing the Seemingly Impossible
ERIC Educational Resources Information Center
Sena, Rachel; Schoorman, Dilys; Bogotch, Ira
2013-01-01
Sister R., the first author, is a Dominican Sister of Peace. Until recently, Sister R. had been the director of the Maya Ministry Family Literacy Program, working with the Maya Community in Lake Worth, Palm Beach County, Florida. She described her work with these indigenous, preliterate, hardworking peoples as "a university of the poor"…
2010-12-01
education , time at sea, and field exercises/alerts. 10. In the past 12 months, how many nights have you been away from your permanent duty station...nmlkj nmlkj b. A friend? nmlkj nmlkj nmlkj c. A family member (e.g., parent , brother/sister)? nmlkj nmlkj nmlkj d. A chaplain...nmlkj nmlkj b. A friend? nmlkj nmlkj nmlkj c. A family member (e.g., parent , brother/sister)? nmlkj nmlkj nmlkj d. A chaplain
A Brief Analysis of Sister Carrie's Character
ERIC Educational Resources Information Center
Yu, Hanying
2010-01-01
Carrie is always dreaming while the rocking chair is rocking again and again, this is the deep impression on us after we read "Sister Carrie" which is the first novel of Theodore Dreiser. In this novel the protagonist Sister Carrie is a controversial person. This paper tries to analyze the character of Sister Carrie in order to find out…
Sibling sex ratio and birth order in early-onset gender dysphoric adolescents.
Schagen, Sebastian E E; Delemarre-van de Waal, Henriette A; Blanchard, Ray; Cohen-Kettenis, Peggy T
2012-06-01
Several sibship-related variables have been studied extensively in sexual orientation research, especially in men. Sibling sex ratio refers to the ratio of brothers to sisters in the aggregate sibships of a group of probands. Birth order refers to the probands' position (e.g., first-born, middle-born, last-born) within their sibships. Fraternal birth order refers to their position among male siblings only. Such research was extended in this study to a large group of early-onset gender dysphoric adolescents. The probands comprised 94 male-to-female and 95 female-to-male gender dysphoric adolescents. The overwhelming majority of these were homosexual or probably prehomosexual. The control group consisted of 875 boys and 914 girls from the TRAILS study. The sibling sex ratio of the gender dysphoric boys was very high (241 brothers per 100 sisters) compared with the expected ratio (106:100). The excess of brothers was more extreme among the probands' older siblings (300:100) than among their younger siblings (195:100). Between-groups comparisons showed that the gender dysphoric boys had significantly more older brothers, and significantly fewer older sisters and younger sisters, than did the control boys. In contrast, the only notable finding for the female groups was that the gender dysphoric girls had significantly fewer total siblings than did the control girls. The results for the male probands were consistent with prior speculations that a high fraternal birth order (i.e., an excess of older brothers) is found in all homosexual male groups, but an elevated sibling sex ratio (usually caused by an additional, smaller excess of younger brothers) is characteristic of gender dysphoric homosexual males. The mechanisms underlying these phenomena remain unknown.
20 CFR 641.841 - What policies govern nepotism?
Code of Federal Regulations, 2011 CFR
2011-04-01
... followed. (c) For purposes of this section, “immediate family” means wife, husband, son, daughter, mother, father, brother, sister, son-in-law, daughter-in-law, mother- in-law, father-in-law, brother-in-law...
Somatomedin C deficiency in Asian sisters.
McGraw, M E; Price, D A; Hill, D J
1986-12-01
Two sisters of Asian origin showed typical clinical and biochemical features of primary somatomedin C (SM-C) deficiency (Laron dwarfism). Abnormalities of SM-C binding proteins were observed, one sister lacking the high molecular weight (150 Kd) protein.
Hall, Sarah A; Rossetti, Zach
2018-05-01
Siblings of people with intellectual and developmental disabilities (IDD) often assume key roles to support their brothers and sisters. For people with more significant support needs, siblings may undertake additional roles and responsibilities throughout their lives. The purpose of the present study was to identify and describe the roles of adult siblings who have a brother or sister with severe IDD. Seventy-nine adult siblings from 19 to 72 years of age completed an online survey with open-ended questions about the roles they play in their relationships with their brother or sister. Thematic analysis resulted in identification of several roles including caregiver, friend (social partner), advocate, legal representative, sibling (teacher/role model), leisure planner and informal service coordinator. Siblings assume key roles in the lives of people with IDD and need support from family and professionals to perform these roles. © 2017 John Wiley & Sons Ltd.
Somatomedin C deficiency in Asian sisters.
McGraw, M E; Price, D A; Hill, D J
1986-01-01
Two sisters of Asian origin showed typical clinical and biochemical features of primary somatomedin C (SM-C) deficiency (Laron dwarfism). Abnormalities of SM-C binding proteins were observed, one sister lacking the high molecular weight (150 Kd) protein. Images Figure PMID:2434036
Eruptive history of South Sister, Oregon Cascades
Fierstein, J.; Hildreth, W.; Calvert, A.T.
2011-01-01
South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt-andesite-dacite cone built between 48 and 14ka, and South Sister is a basalt-free edifice that alternated rhyolitic and intermediate modes from 50ka to 2ka (largely contemporaneous with Middle Sister). Detailed mapping, 330 chemical analyses, and 42 radioisotopic ages show that the oldest exposed South Sister lavas were initially rhyolitic ~50ka. By ~37ka, rhyolitic lava flows and domes (72-74% SiO2) began alternating with radially emplaced dacite (63-68% SiO2) and andesite (59-63% SiO2) lava flows. Construction of a broad cone of silicic andesite-dacite (61-64% SiO2) culminated ~30ka in a dominantly explosive sequence that began with crater-forming andesitic eruptions that left fragmental deposits at least 200m thick. This was followed at ~27ka by growth of a steeply dipping summit cone of agglutinate-dominated andesite (56-60.5% SiO2) and formation of a summit crater ~800m wide. This crater was soon filled and overtopped by a thick dacite lava flow and then by >150m of dacitic pyroclastic ejecta. Small-volume dacite lavas (63-67% SiO2) locally cap the pyroclastic pile. A final sheet of mafic agglutinate (54-56% SiO2) - the most mafic product of South Sister - erupted from and drapes the small (300-m-wide) present-day summit crater, ending a summit-building sequence that lasted until ~22ka. A 20kyr-long-hiatus was broken by rhyolite eruptions that produced (1) the Rock Mesa coulee, tephra, and satellite domelets (73.5% SiO2) and (2) the Devils Chain of ~20 domes and short coulees (72.3-72.8% SiO2) from N-S vent alignments on South Sister's flanks. The compositional reversal from mafic summit agglutinate to recent rhyolites epitomizes the frequently changing compositional modes of the
Eruptive history of South Sister, Oregon Cascades
NASA Astrophysics Data System (ADS)
Fierstein, Judy; Hildreth, Wes; Calvert, Andrew T.
2011-10-01
South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20 km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt-andesite-dacite cone built between 48 and 14 ka, and South Sister is a basalt-free edifice that alternated rhyolitic and intermediate modes from 50 ka to 2 ka (largely contemporaneous with Middle Sister). Detailed mapping, 330 chemical analyses, and 42 radioisotopic ages show that the oldest exposed South Sister lavas were initially rhyolitic ~ 50 ka. By ~ 37 ka, rhyolitic lava flows and domes (72-74% SiO 2) began alternating with radially emplaced dacite (63-68% SiO 2) and andesite (59-63% SiO 2) lava flows. Construction of a broad cone of silicic andesite-dacite (61-64% SiO 2) culminated ~ 30 ka in a dominantly explosive sequence that began with crater-forming andesitic eruptions that left fragmental deposits at least 200 m thick. This was followed at ~ 27 ka by growth of a steeply dipping summit cone of agglutinate-dominated andesite (56-60.5% SiO 2) and formation of a summit crater ~ 800 m wide. This crater was soon filled and overtopped by a thick dacite lava flow and then by > 150 m of dacitic pyroclastic ejecta. Small-volume dacite lavas (63-67% SiO 2) locally cap the pyroclastic pile. A final sheet of mafic agglutinate (54-56% SiO 2) - the most mafic product of South Sister - erupted from and drapes the small (300-m-wide) present-day summit crater, ending a summit-building sequence that lasted until ~ 22 ka. A 20 kyr-long-hiatus was broken by rhyolite eruptions that produced (1) the Rock Mesa coulee, tephra, and satellite domelets (73.5% SiO 2) and (2) the Devils Chain of ~ 20 domes and short coulees (72.3-72.8% SiO 2) from N-S vent alignments on South Sister's flanks. The compositional reversal from mafic summit agglutinate to recent rhyolites epitomizes the frequently
Drs. Smith Brothers: dental surgeons of Calcutta.
Sanjeev, Kumar
2014-01-01
During the British raj, India attracted dental practitioners from all over the world who set up practices in the Presidency towns of Calcutta, Bombay, Madras and Bangalore. Lured by the abundant opportunity to make good money, these mercenary but courageous dentists counted Viceroys, Indian royalty and political leaders amongst their clients. Some, like the famous American Smith Brothers of Calcutta, were sought after even by the rulers of neighboring countries. Dr. Mark Smith's hazardous visit to the Amir of Afghanistan made worldwide headlines more than 100 years ago for the fabulous fee he was paid for the dental treatment. This paper briefly describes the exploits and experiences of the Smith brothers while in India.
Biswas, Sadaruddin; Koziel, Slawomir; Chakraborty, Raja; Bose, Kaushik
2013-08-01
Menarche, the first menstruation, is one of the most important events in a woman's reproductive life. The timing of menarche varies across populations and depends upon social interaction and family environment. It is also associated with several biological as well as social factors. The objective of this study was to explore the relationship between sibling composition and age at menarche (AAM) and to assess the association between the pattern of room sharing with family members of different sexes and menarcheal occurrence among rural Bengalee girls from West Bengal, India. The total sample comprised 577 Bengalee girls, 6-17 years of age, from various schools and madrasas in two blocks of the Nadia District of West Bengal State in India. The effects of room sharing on the occurrence of menarche, and of sibling composition on the menarcheal age, were assessed by analyses of covariance. The room-sharing pattern had a significant effect on menarcheal status (yes÷no): a significantly higher percentage of girls who shared a room with the mother and÷or sisters were postmenarcheal compared with those who shared a room with male family members. AAM did not differ significantly between girls having brothers or sisters. However, sibling order had a significant impact on AAM. Girls who had a younger sibling only (brother or sister) had a higher mean AAM, and girls who had both younger brothers and younger sisters had significantly higher mean AAM, than did the girls who had no younger sibling (singletons or having only elder siblings). There was no difference in AAM between the girls who had younger sister(s) and those who had younger brother(s). These differences were also independent of body mass index. In conclusion, the room sharing characteristics and the sibling sex composition, particularly their order, had significant effect on menarche in adolescent rural Bengalee girls. Copyright © 2013 Wayne State University Press, Detroit, Michigan 48201-1309.
ERIC Educational Resources Information Center
Obama, Barack
2014-01-01
In a White House address, the president announced an initiative to reclaim young boys and men of color. The "My Brother's Keeper" initiative partners with businesses, foundations, and nonprofits to address disparities in education, justice, and employment. President Obama was introduced by Christian, one of a group of students from…
Scott Brothers Windows and Doors Information Sheet
Scott Brothers Windows and Doors (the Company) is located in Bridgeville, Pennsylvania. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Pittsburgh, Pennsylvania.
Acral peeling skin syndrome: a case of two brothers.
Wakade, Oojwala; Adams, Beth; Shwayder, Tor
2009-01-01
We report two brothers of Middle Eastern descent with consanguineous parents who present with numerous fragile, flaccid blisters on the hands and feet. In addition to spontaneous peeling, they can manually peel skin from acral areas without pain. The symptoms worsen with warm temperatures, excessive water exposure, and perspiration. Two biopsies from flaccid blisters on the feet were taken from the older brother, which revealed cleavage at the level of the stratum corneum. A diagnosis of acral peeling skin syndrome was made.
The Lay Sister in Educational History and Memory.
ERIC Educational Resources Information Center
Jack, Christine Trimingham
2000-01-01
Focuses on the construction of lay sisters in a religious order and school setting using a poststructuralist orientation. Explains that in the study documents were examined and interviews were conducted with ex-students, choir nuns, and a lay sister at a small Catholic girls-preparatory boarding school. Explores the narrative of one lay sister.…
Perez-Brena, Norma J; Wheeler, Lorey A; Updegraff, Kimberly A; Schaefer, David R
2015-07-01
This study examined the role of sibling and friend characteristics in Mexican-American youth's gender-typed characteristics (i.e., attitudes, interests, and leisure activities) in early versus middle adolescence using a sibling design. Mexican-American 7th graders (M = 12.51 years; SD = .58) and their older siblings (M = 15.48 years; SD = 1.57) from 246 families participated in home interviews and a series of seven nightly phone calls. Results revealed that younger/early adolescent siblings reported more traditional gender role attitudes than their older/middle adolescent siblings and older brothers were more traditional in their attitudes than older sisters. When comparing siblings' gender-typed interests and leisure activities, boys reported more masculine orientations than girls and girls reported more feminine orientations than boys. Older brothers' gender-typed characteristics were associated with the amount of time spent with and gender characteristics of their friendship group, but for younger brothers, sibling characteristics were associated with their gender-typed characteristics. In contrast, both sibling and friendship characteristics were significantly associated with older and younger sisters' gender-typed characteristics. The discussion addressed the different correlates of older and younger sisters' and brothers' gender-typed characteristics.
Zucker, Kenneth J; Blanchard, Ray; Kim, Tae-Suk; Pae, Chi-Un; Lee, Chul
2007-10-01
Two biodemographic variables - birth order and sibling sex ratio - have been examined in several Western samples of homosexual transsexual men. The results have consistently shown that homosexual transsexuals have a later birth order and come from sibships with an excess of brothers to sisters; the excess of brothers has been largely driven by the number of older brothers and hence has been termed the fraternal birth order effect. In the present study the birth order and sibling sex ratio were examined in an Asian sample of 43 homosexual transsexual men and 49 heterosexual control men from South Korea. Although the transsexual men had a significantly late birth order, so did the control men. Unlike Western samples, the Korean transsexuals had a significant excess of sisters, not brothers, as did the control men, and this was largely accounted for by older sisters. It is concluded that a male-preference stopping rule governing parental reproductive behavior had a strong impact on these two biodemographic variables. Future studies that examine birth order and sibling sex ratio in non-Western samples of transsexuals need to be vigilant for the influential role of stopping rules, including the one identified in the present study.
Rate of Family Violence Among Patients With Schizophrenia in Japan.
Kageyama, Masako; Yokoyama, Keiko; Nagata, Satoko; Kita, Sachiko; Nakamura, Yukako; Kobayashi, Sayaka; Solomon, Phyllis
2015-09-01
Family violence is a serious concern in the era of deinstitutionalization in Japan. Consequently, we aimed to clarify the rate of family violence among patients with schizophrenia, and differences by sex and relationship to the patient. We asked households belonging to a family group association to complete a self-administered mail survey. Of 350 households that responded, data for 302 were analyzed. The rate of violence toward any family member was 60.9% over the lifetime and 27.2% in the past year. Order of lifetime rates for family members from highest to lowest was 51.0% for mothers, 47.0% for fathers, 30.7% for younger sisters, 23.8% for spouses, 19.5% for younger brothers, 18.2% for older sisters, 17.1% for older brothers, and none for children. Younger sisters were more likely to be victims compared to other siblings. Fathers and older brothers were likely to be victims when patients were male. © 2015 APJPH.
Incest, gamete donation by siblings and the importance of the genetic link.
Pennings, G
2002-01-01
Recently, several requests have emerged in which women wished to be impregnated with donor eggs fertilized with spermatozoa of their brother. An important argument advanced against such applications is that it is a kind of incest. Four definitions of incest are reviewed in this article to evaluate the acceptability of these demands. The first three (sexual intercourse, reproduction with gametes of first-degree relatives and symbolic incest) do not apply to the cases. However, when the sister and her brother intend to raise the child as social mother and father, these requests should be considered as "intentional incest". If the brother only functions as an uncle, the request of the woman resembles the currently accepted practice of oocyte donation from sister to sister. In that case, the wish to receive gametes from a first-degree relative is motivated by the wish to establish as far as possible a genetic link with the child.
Association among number, order and type of siblings and adolescent mental health at age 12.
Liu, Jufen; Sekine, Michikazu; Tatsuse, Takashi; Fujimura, Yuko; Hamanishi, Shimako; Zheng, Xiaoying
2015-10-01
Although the sibling relationship is a unique one, the effects of the number and type of siblings on mental health among adolescents have not been reported. Japanese children (total, 9276; boys, 4654; girls, 4622), all 12 years old, and from the Japanese Toyama Birth Cohort Study, were followed up until 2002. Subject self-reported mental health was obtained from the Japanese version of the Dartmouth Primary Care Co-operative Project (COOP) charts. The associations between number and type of siblings and self-reported mental health were examined. There was a significant difference in mental health between different sibling pairs, with brother pairs and brother/sister pairs having a positive effect on adolescent mental health, compared with those in sister pairs. Girls with brothers had better self-reported mental health than those without. The adjusted OR of good mental health was 1.44 (95%CI:1.00-2.08) for those with an older brother and 1.67 (95%CI: 1.17-2.38) for those with a younger brother compared with those without. Boys with a younger sister had a higher OR of good self-reported health than those without (OR, 1.62; 95%CI: 1.08-2.43). Children with siblings had better mental health status than those without, which has practical implications for Asian countries and worldwide considering the declining fertility. © 2015 Japan Pediatric Society.
Sexually Antagonistic Zygotic Drive: A New Form of Genetic Conflict between the Sex Chromosomes
Friberg, Urban; Rice, William R.
2015-01-01
Sisters and brothers are completely unrelated with respect to the sex chromosomes they inherit from their heterogametic parent. This has the potential to result in a previously unappreciated form of genetic conflict between the sex chromosomes, called sexually antagonistic zygotic drive (SA-ZD). SA-ZD can arise whenever brothers and sisters compete over limited resources or there is brother–sister mating coupled with inbreeding depression. Although theory predicts that SA-ZD should be common and influence important evolutionary processes, there is little empirical evidence for its existence. Here we discuss the current understanding of SA-ZD, why it would be expected to elude empirical detection when present, and how it relates to other forms of genetic conflict. PMID:25573714
Mortality and health-related habits in 900 Finnish former elite athletes and their brothers.
Kontro, Titta Katariina; Sarna, Seppo; Kaprio, Jaakko; Kujala, Urho M
2018-01-01
There is conflicting evidence on the associations between participation in vigorous sports, health habits, familial factors and subsequent mortality. We investigated all-cause mortality and health-related behaviour among former elite athletes and their brothers. The mortality of Finnish male former elite athletes, who had represented Finland between 1920 and 1965 (n=900) and their age-matched brothers (n=900), was followed from the time when athlete started an elite athlete career until 31 December 2015. The age-adjusted HRs were calculated by a paired Cox proportional hazards model. In 2001, surviving participants (n=199 athletes and n=199 age-matched brothers) reported their self-rated health (SRH), physical activity, alcohol consumption and smoking habits in the questionnaire. During the total follow-up period, 1296 deaths (72% of the cohort) occurred. The age-adjusted HRs for all-cause mortality in former athletes was 0.75 (95% CI 0.65 to 0.87, P<0.001) compared with their age-matched brothers. Median age at death was 79.9 years for endurance, 75.9 years for mixed sports and 72.2 years for power sports athletes, and 77.5, 73.7 and 72.2 years for their age-matched brothers, respectively. In 2001, compared with their brothers, former athletes smoked less (P<0.001), were more physically active (P<0.05) and rated their health more often as very good (P<0.05). Former elite athletes are more physically active, smoke less, have better self-rated health and live longer than their brothers. Genetic differences between athletes and brothers, aerobic training for endurance elite sports and a healthier lifestyle may all contribute to reduced mortality. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Crocodile Talk: Attributions of Incestuously Abused and Nonabused Sisters.
ERIC Educational Resources Information Center
Monahan, Kathleen
1997-01-01
This qualitative study analyzed the retrospective attributions of adult sisters (five abused sister dyads, and five abused and nonabused sister dyads) who grew up in incestuous families. It examined the attributions of subjects regarding the general sibling group; victim selection and nonselection; and attributions regarding jealousy, protection,…
Raj, Anita; McDougal, Lotus P; Silverman, Jay G
2015-01-01
This study examines the effects of number and sex of siblings on malnutrition of boys and girls under-5 in South Asia. Cross-sectional analyses were conducted on Demographic and Health Surveys data on children under-5 in Bangladesh (N = 7,861), India (N = 46,655) and Nepal (N = 2,475). Data were pooled across countries, and multinomial logistic regression was used to assess the relationship between number and sex of siblings and malnutrition outcomes (wasting, stunting, underweight; based on anthropometric data), adjusting for country and key social and maternal-child health indicators in sex stratified analyses. Number of brothers increased the odds for severe wasting [1 vs. 0 brothers adjusted odds ratio (AOR) = 1.31, 95 % CI = 1.11, 1.55; 2 vs. 0 brothers AOR = 1.36, 95 % CI = 1.07, 1.73] for girls but not boys. Having more male siblings and more female siblings increased the odds of stunting for boys and girls, but effect of 3+ sisters on severe stunting was significantly stronger for girls than boys (girls- 3+ vs. 0 sisters AOR = 2.25, 95 % CI = 1.88, 2.70; boys- 3+ vs. 0 sisters AOR = 1.37, 95 % CI = 1.13, 1.67). For underweight, three or more sisters increased the odds for severe underweight for girls (AOR = 1.27, 95 % CI = 1.04, 1.57) but not boys. Having brothers heightens girl risk for acute malnutrition (wasting), where having multiple sisters increases girl risk for chronic malnutrition (stunting/underweight). Boy malnutrition is less affected by siblings. Findings suggest that issues of son preference/daughter aversion may affect child malnutrition in South Asia.
Wright Brothers National Memorial : acoustical monitoring 2011
DOT National Transportation Integrated Search
2014-11-01
During the winter of 2011(September - November) baseline acoustical data were collected at Wright Brothers National Memorial (WRBR) at two sites deployed for approximately 30 days each. The baseline data collected during these periods will help park ...
Developing skills in clinical leadership for ward sisters.
Fenton, Katherine; Phillips, Natasha
The Francis report has called for a strengthening of the ward sister's role. It recommends that sisters should operate in a supervisory capacity and should not be office bound. Effective ward leadership has been recognised as being vital to high-quality patient care and experience, resource management and interprofessional working. However, there is evidence that ward sisters are ill equipped to lead effectively and lack confidence in their ability to do so. University College London Hospitals Foundation Trust has recognised that the job has become almost impossible in increasingly large and complex organisations. Ward sisters spend less than 40% of their time on clinical leadership and the trust is undertaking a number of initiatives to support them in this role.
Volcano hazards in the Three Sisters region, Oregon
Scott, William E.; Iverson, R.M.; Schilling, S.P.; Fisher, B.J.
2001-01-01
Three Sisters is one of three potentially active volcanic centers that lie close to rapidly growing communities and resort areas in Central Oregon. Two types of volcanoes exist in the Three Sisters region and each poses distinct hazards to people and property. South Sister, Middle Sister, and Broken Top, major composite volcanoes clustered near the center of the region, have erupted repeatedly over tens of thousands of years and may erupt explosively in the future. In contrast, mafic volcanoes, which range from small cinder cones to large shield volcanoes like North Sister and Belknap Crater, are typically short-lived (weeks to centuries) and erupt less explosively than do composite volcanoes. Hundreds of mafic volcanoes scattered through the Three Sisters region are part of a much longer zone along the High Cascades of Oregon in which birth of new mafic volcanoes is possible. This report describes the types of hazardous events that can occur in the Three Sisters region and the accompanying volcano-hazard-zonation map outlines areas that could be at risk from such events. Hazardous events include landslides from the steep flanks of large volcanoes and floods, which need not be triggered by eruptions, as well as eruption-triggered events such as fallout of tephra (volcanic ash) and lava flows. A proximal hazard zone roughly 20 kilometers (12 miles) in diameter surrounding the Three Sisters and Broken Top could be affected within minutes of the onset of an eruption or large landslide. Distal hazard zones that follow river valleys downstream from the Three Sisters and Broken Top could be inundated by lahars (rapid flows of water-laden rock and mud) generated either by melting of snow and ice during eruptions or by large landslides. Slow-moving lava flows could issue from new mafic volcanoes almost anywhere within the region. Fallout of tephra from eruption clouds can affect areas hundreds of kilometers (miles) downwind, so eruptions at volcanoes elsewhere in the
John Bell (1763-1820): brother artist and anatomist.
Gardner-Thorpe, Christopher
2013-01-01
John Bell, brother-surgeon of Charles Bell, was, like Charles, an outstanding surgeon and a good artist. John was one of the few who illustrated his work with their own drawings in the days before audiovisual aids were available and without the benefit of reliable drawing aids, photography and computer-aided design. Charles, on the other hand, was the better artist and illustrated much of the normal anatomy of the nervous system. Each brother undertook extensive surgery of men who had been wounded in war; John Bell left us his engravings from the textbooks, more numerous perhaps than Charles, but Charles left us a series of oil paintings and watercolours in addition to the illustrations in his textbooks. © 2013 Elsevier B.V. All rights reserved.
Family and sexual orientation: the family-demographic correlates of homosexuality in men and women.
Francis, Andrew M
2008-01-01
Using a nationally representative sample of young adults, I identify the family-demographic correlates of sexual orientation in men and women. Hence, I test the maternal immune hypothesis, which posits that the only biodemographic correlate of male homosexuality is the number of older brothers, and there are no biodemographic correlates of female homosexuality. For men, I find that having one older brother does not raise the likelihood of homosexuality. Although having multiple older brothers has a positive coefficient, it is not significant. Moreover, having any older sisters lowers the likelihood of homosexual or bisexual identity. For women, I find that having an older brother or having any sisters decreases the likelihood of homosexuality. Family structure, ethnicity, and education are also significantly correlated with male and female sexual orientation. Therefore, the maternal immune hypothesis cannot explain the entire pattern of family-demographic correlates. The findings are consistent with either biological or social theories of sexual orientation.
Bram Stoker's brother, the brain surgeon.
Stiles, Anne
2013-01-01
This essay examines the life and work of Sir William Thornley Stoker, 1st Baronet (1845-1912), the eldest brother of Bram Stoker (1847-1912), the author of Dracula (1897). Sir William or "Thornley," as he was commonly known, was one of Ireland's leading physicians. He performed some of the first brain surgeries in Ireland using Sir David Ferrier's maps of the cerebral cortex. From 1879 into the twentieth century, Thornley served as inspector for Ireland under the 1876 Cruelty to Animals Act. In this role, Thornley was responsible for granting licenses to researchers who performed experiments on live animals. Due to his reservations about animal experimentation, Thornley eventually became an advocate for the antivivisection cause, testifying at the second Royal Commission on Vivisection (1906-1912). Thornley also influenced Irish literature, albeit indirectly. Bram Stoker's composition notes for Dracula show that he consulted his older brother about the medical scenes in his novel. Thornley's knowledge of cerebral localization and his animal rights advocacy both surface in Dracula. © 2013 Elsevier Inc. All rights reserved.
Build Your Own Wright Brothers' Glider
ERIC Educational Resources Information Center
Schimmel, Gordon; Hand, Jon; Ellis, Art
2003-01-01
A little more than one hundred years ago, Wilbur and Orville Wright began building models of airfoils and testing them in wind tunnels in their search for an efficient wing. Models continue to be used today by aerospace engineers to prove concepts and launch dreams. To celebrate the centennial of the Wright brothers' historic flight, the authors…
Gliding Experiments of the Wright Brothers: The Wrights and Flight Research 1899-1908
NASA Technical Reports Server (NTRS)
Bowers, Al; Cole, Jennifer Hansen; Martin, Cam
2008-01-01
This viewgraph presentation reviews the Wright Brothers's flight research during the 10 years between 1899 and 1908. The Wright Brothers began their research in flight with gliders. The presentation shows pictures, replicas and characteristics of the gliders that the Wright Brothers used. This presentation is not just a history lesson. In the end it investigates "What Does Flight Research Accomplish?" Flight research can serve many uses, such as Separates the Real from the Imagined, Uncovers the Unexpected and the Overlooked, Forces the Realistic Integration of the Pilot, Forces the Development of Reliable Prediction and Test Processes, Requires Every Problem to Be Addressed, Promotes Technology Transfer, and Builds a Core Technical Team,
Blattner, Ariane C; Chaurasia, Soumya; McKee, Bruce D; Lehner, Christian F
2016-04-01
Spatially controlled release of sister chromatid cohesion during progression through the meiotic divisions is of paramount importance for error-free chromosome segregation during meiosis. Cohesion is mediated by the cohesin protein complex and cleavage of one of its subunits by the endoprotease separase removes cohesin first from chromosome arms during exit from meiosis I and later from the pericentromeric region during exit from meiosis II. At the onset of the meiotic divisions, cohesin has also been proposed to be present within the centromeric region for the unification of sister centromeres into a single functional entity, allowing bipolar orientation of paired homologs within the meiosis I spindle. Separase-mediated removal of centromeric cohesin during exit from meiosis I might explain sister centromere individualization which is essential for subsequent biorientation of sister centromeres during meiosis II. To characterize a potential involvement of separase in sister centromere individualization before meiosis II, we have studied meiosis in Drosophila melanogaster males where homologs are not paired in the canonical manner. Meiosis does not include meiotic recombination and synaptonemal complex formation in these males. Instead, an alternative homolog conjunction system keeps homologous chromosomes in pairs. Using independent strategies for spermatocyte-specific depletion of separase complex subunits in combination with time-lapse imaging, we demonstrate that separase is required for the inactivation of this alternative conjunction at anaphase I onset. Mutations that abolish alternative homolog conjunction therefore result in random segregation of univalents during meiosis I also after separase depletion. Interestingly, these univalents become bioriented during meiosis II, suggesting that sister centromere individualization before meiosis II does not require separase.
Splitting the chromosome: cutting the ties that bind sister chromatids.
Nasmyth, K; Peters, J M; Uhlmann, F
2000-05-26
In eukaryotic cells, sister DNA molecules remain physically connected from their production at S phase until their separation during anaphase. This cohesion is essential for the separation of sister chromatids to opposite poles of the cell at mitosis. It also permits chromosome segregation to take place long after duplication has been completed. Recent work has identified a multisubunit complex called cohesin that is essential for connecting sisters. Proteolytic cleavage of one of cohesin's subunits may trigger sister separation at the onset of anaphase.
Blattner, Ariane C.; McKee, Bruce D.; Lehner, Christian F.
2016-01-01
Spatially controlled release of sister chromatid cohesion during progression through the meiotic divisions is of paramount importance for error-free chromosome segregation during meiosis. Cohesion is mediated by the cohesin protein complex and cleavage of one of its subunits by the endoprotease separase removes cohesin first from chromosome arms during exit from meiosis I and later from the pericentromeric region during exit from meiosis II. At the onset of the meiotic divisions, cohesin has also been proposed to be present within the centromeric region for the unification of sister centromeres into a single functional entity, allowing bipolar orientation of paired homologs within the meiosis I spindle. Separase-mediated removal of centromeric cohesin during exit from meiosis I might explain sister centromere individualization which is essential for subsequent biorientation of sister centromeres during meiosis II. To characterize a potential involvement of separase in sister centromere individualization before meiosis II, we have studied meiosis in Drosophila melanogaster males where homologs are not paired in the canonical manner. Meiosis does not include meiotic recombination and synaptonemal complex formation in these males. Instead, an alternative homolog conjunction system keeps homologous chromosomes in pairs. Using independent strategies for spermatocyte-specific depletion of separase complex subunits in combination with time-lapse imaging, we demonstrate that separase is required for the inactivation of this alternative conjunction at anaphase I onset. Mutations that abolish alternative homolog conjunction therefore result in random segregation of univalents during meiosis I also after separase depletion. Interestingly, these univalents become bioriented during meiosis II, suggesting that sister centromere individualization before meiosis II does not require separase. PMID:27120695
Blanchard, Ray
2018-01-01
The fraternal birth order effect is the tendency for older brothers to increase the odds of homosexuality in later-born males. This study compared the strength of the effect in subjects from small versus large families and in homosexual subjects with masculine versus feminine gender identities. Meta-analyses were conducted on 30 homosexual and 30 heterosexual groups from 26 studies, totaling 7140 homosexual and 12,837 heterosexual males. The magnitude of the fraternal birth order effect was measured with a novel variable, the Older Brothers Odds Ratio, computed as (homosexuals' older brothers ÷ homosexuals' other siblings) ÷ (heterosexuals' older brothers ÷ heterosexuals' other siblings), where other siblings = older sisters + younger brothers + younger sisters. An Older Brothers Odds Ratio of 1.00 represents no effect of sexual orientation; values over 1.00 are positive evidence for the fraternal birth order effect. Evidence for the reliability of the effect was consistent. The Older Brothers Odds Ratio was significantly >1.00 in 20 instances, >1.00 although not significantly in nine instances, and nonsignificantly <1.00 in 1 instance. The pooled Older Brothers Odds Ratio for all samples was 1.47, p < .00001. Subgroups analyses showed that the magnitude of the effect was significantly greater in the 12 feminine or transgender homosexual groups than in the other 18 homosexual groups. There was no evidence that the magnitude of the effect differs according to family size.
little sister: An Afro-Temporal Solo-Play.
De Berry, Misty
2017-07-03
little sister: An Afro-Temporal Solo-Play is at once a memory-scape and a mytho-biography set to poetry, movement, and mixed media. A performance poem spanning from the Antebellum South to present-moment Chicago, it tells the story of a nomadic spirit named little-she who shape-shifts through the memories and imaginings of her sister, the narrator. Through the characters little-she and the narrator, the solo-performance explores embodied ways to rupture and relieve the impact of macro forms of violence in the micro realm of the everyday. To this end, little sister witnesses and disrupts the legacy of violence in the lives of queer Black women through a trans-temporal navigation of everyday encounters within familial, small groups and intimate partner spaces.
NASA Astrophysics Data System (ADS)
Bartlett, D. F.
2005-05-01
Simulations of the formation of the Oort cloud from the Kuiper Belt typically are presented as an animated scatter diagram. Here the orbit of each object appears as a point of perihelion distance q and semi-major axis a. (eg. Levison, Morbidelli, & Dones 2004). These plots show a conspicuous void, bounded by the inequalities: q < a, q > 50 AU, and a < 5000-10000 AU. Brown (2005) calls this void the ``Bermuda Triangle". The only present occupant is Sedna (q=76 AU, a=501 AU). Brown, Trujillo, & Rabinowitz , the discovers of Sedna, have challenged others to explain how Sedna got inside the triangle and to predict where similar objects might be found. Sedna could not have simply formed in its current orbit by the accumulation of smaller objects (Stern 2005). Several authors have suggested that a passing star scattered Sedna into the triangle shortly after the birth of the solar system. Here I offer an alternative which uses the very strong galactic tidal forces of the Sinusoidal potential (Bartlett 2001, 2004). In this potential, the numerator of Newton's law is replaced by GM cos(ko r) where ko = 2 π / lambdao and the 'wavelength' λ o is 425 pc. The 20 radial oscillations between the sun and the center of the Galaxy give tidal forces that are 120 times as big as generally expected. I will show how this tidal force, acting over the lifetime of the solar system, could move the perihelion of Sedna from about 40 to 76 AU. Sedna's sisters are likely to have still larger q & a and to have perihelia in two specific quadrants of the ecliptic plane.
Sister chromatid segregation in meiosis II
Wassmann, Katja
2013-01-01
Meiotic divisions (meiosis I and II) are specialized cell divisions to generate haploid gametes. The first meiotic division with the separation of chromosomes is named reductional division. The second division, which takes place immediately after meiosis I without intervening S-phase, is equational, with the separation of sister chromatids, similar to mitosis. This meiotic segregation pattern requires the two-step removal of the cohesin complex holding sister chromatids together: cohesin is removed from chromosome arms that have been subjected to homologous recombination in meiosis I and from the centromere region in meiosis II. Cohesin in the centromere region is protected from removal in meiosis I, but this protection has to be removed—deprotected”—for sister chromatid segregation in meiosis II. Whereas the mechanisms of cohesin protection are quite well understood, the mechanisms of deprotection have been largely unknown until recently. In this review I summarize our current knowledge on cohesin deprotection. PMID:23574717
Eriksen, Willy; Sundet, Jon M; Tambs, Kristian
2013-05-01
We examined the relationship between the parents' education levels and the adult intelligence of their children in a population-based, nationwide sample of Norwegian half-brothers with different fathers (2,016 pairs of half-brothers). In a family where the mother has two children with different men, the firstborn child usually lives with the younger child's father during a period of their childhood. This makes it possible to study the non-genetic effects of paternal education on children's development. Results showed that the education level of the younger half-brother's father was positively associated with the intelligence score of the older half-brother. The education level of the older half-brother's father was not associated with the intelligence score of the younger half-brother. Firstborn men whose half-brothers' fathers had high levels of education had intelligence scores that were 33% (95% confidence interval: 18-47%) of a standard deviation higher than those of firstborn men whose half-brothers' fathers had low levels of education, after adjustment for the biological fathers' education levels, mothers' education levels, and other background factors. These findings are compatible with the hypothesis that a child's family environment exerts an effect on the cognitive abilities of the child that lasts into adulthood. © 2012 The British Psychological Society.
Teletext--Prestel's Big Brother.
ERIC Educational Resources Information Center
Hughes, Geoffrey
Prestel, Oracle, and Ceefax are telephone based video text systems currently in use in Great Britain. Rather than being considered as competitors, they should be viewed as complementary media with separate functions based on their differences. All use home television sets to receive information in print, and all broadcast on spare TV lines in the…
Nolan, M
1994-11-01
Young children who are about to attend the birth of a sibling must be thoroughly prepared for the sights and sounds of labour. It is helpful if the child can get to know the midwife who will be with his mother during her labour. A young child needs a support person during the labour who can answer his questions and go with him if he wishes to leave the birthing room. A child who has seen his sibling being born may be very protective of her. Being present at a birth may help children to come to terms with their own sexuality later in life. There is no evidence of short or long-term psychological damage to children who have witnessed the birth of a sibling. Women who choose to have their children present during their labour have generally thought out their reasons very carefully beforehand.
ERIC Educational Resources Information Center
Heinen, Edward
1983-01-01
Cites the recent United States State Department's labeling of recent Canadian films--one on nuclear war and two on acid rain--as political propaganda as a sign of the need to review the nature of propaganda. Suggests that teaching students to intelligently evaluate propaganda is preferable to submitting to government dictum. (MM)
Sibling composition during childhood and adult blood pressure among native Amazonians in Bolivia.
Zeng, Wu; Undurraga, Eduardo A; Nyberg, Colleen; Eisenberg, Dan T A; Parida, Sabita; Zycherman, Ariela; Magvanjav, Oyunbileg; Reyes-García, Victoria; Tanner, Susan; Godoy, Ricardo
2013-07-01
Sibling configuration, including birth order, or the number, age, and sex of siblings is associated with parental resource allocation between children and is thus associated with a person's well-being. Little is known about the association between specific types of siblings and adult health outcomes. Here we test several hypotheses about sibling composition (number of older brothers, older sisters, younger sisters, younger brothers) and adult blood pressure in a foraging-farming society of native Amazonians in Bolivia (Tsimane'). We collected data in 2007 from 374 adults (16-60years of age) from 196 households in 13 villages. Household random-effects multiple regressions were run using systolic (SBP) or diastolic blood pressure (DBP) as outcomes; covariates included the four sibling categories and control variables (e.g., sex, age, education, body mass index [BMI]). Mean SBP and DBP were 114 (SD=14) and 66 (SD=11)mmHg. The prevalence of hypertension was 5.08%. Having an additional younger brother bore a small (3.3-5.9%) positive association with both SBP and DBP, with the effect weakening as people aged. Having an additional younger sister was associated with a small (3.8%) increase in SBP among women, with the magnitude shrinking as people aged. In a large family, the number of younger brothers may exert an impact on an individual's blood pressure. Copyright © 2012 Elsevier B.V. All rights reserved.
Gliding Experiments of the Wright Brothers: The Wrights and Flight Research 1899-1908
NASA Technical Reports Server (NTRS)
Bowers, Albion H.; Hansen, Jennifer; Martin, Cam
2007-01-01
Viewgraphs showing glider experiments of the Wright Brothers from 1899-1908 are presented. The slides review the experiments that the Wright Brothers conducted prior to their first powered flight in 1903 to developing the first practical aircraft in 1905. Many pictures of the gliders and other devices are used to illustrate the gradual development and experimentation that preceeded the first powered flight.
76 FR 79019 - Wright Brothers Day, 2011
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-20
... Brothers Day, 2011 Memorandum of December 15, 2011--Determinations Under Section 1106(a) of the Omnibus... Day, 2011 By the President of the United States of America A Proclamation On a blustery December... developing the basic controls for pitch, roll, and yaw that, to this day, guide our jetliners to every corner...
78 FR 76969 - Wright Brothers Day, 2013
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-19
... champion STEM education in their communities. As we remember the Wright brothers, let us not forget another... results. That is why my Administration is dedicated to improving education in the vital fields of science... underrepresented groups, and through Race to the Top, we are raising standards and making STEM education a priority...
46 CFR 169.307 - Plans for sister vessels.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Plans for sister vessels. 169.307 Section 169.307 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Construction and Arrangement Plans § 169.307 Plans for sister vessels. Plans are not required for any vessel...
46 CFR 169.307 - Plans for sister vessels.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 7 2011-10-01 2011-10-01 false Plans for sister vessels. 169.307 Section 169.307 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Construction and Arrangement Plans § 169.307 Plans for sister vessels. Plans are not required for any vessel...
Building International Relations for Children through Sister Schools.
ERIC Educational Resources Information Center
Pryor, Carolyn B.
1992-01-01
Inspired by Sister Cities International and the NASSP's school-to-school exchange program, "sister school" pairings have proved to be workable educational programs with long-range impact on participants. Some post-cold war efforts include U.S.-USSR High School Academic Partnerships, Project Harmony, and Center for U.S.-USSR Initiatives.…
The Effect of Siblings' Education on School-Entry in the Ethiopian Highlands
ERIC Educational Resources Information Center
Lindskog, Annika
2013-01-01
The effects of sisters' and brothers' education on the annual school entry probability of boys and girls in rural Amhara are estimated, using within-household variation. There are negative effects of younger siblings' school attendance on girls' school entry, and positive effects of older brothers' literacy only when they have left school. This is…
The Sister Study Cohort: Baseline Methods and Participant Characteristics
Hodgson, M. Elizabeth; Deming-Halverson, Sandra L.; Juras, Paula S.; D’Aloisio, Aimee A.; Suarez, Lourdes M.; Kleeberger, Cynthia A.; Shore, David L.; DeRoo, Lisa A.; Taylor, Jack A.; Weinberg, Clarice R.
2017-01-01
Background: The Sister Study was designed to address gaps in the study of environment and breast cancer by taking advantage of more frequent breast cancer diagnoses among women with a sister history of breast cancer and the presumed enrichment of shared environmental and genetic exposures. Objective: The Sister Study sought a large cohort of women never diagnosed with breast cancer but who had a sister (full or half) diagnosed with breast cancer. Methods: A multifaceted national effort employed novel strategies to recruit a diverse cohort, and collected biological and environmental samples and extensive data on potential breast cancer risk factors. Results: The Sister Study enrolled 50,884 U.S. and Puerto Rican women 35–74y of age (median 56 y). Although the majority were non-Hispanic white, well educated, and economically well off, substantial numbers of harder-to-recruit women also enrolled (race/ethnicity other than non-Hispanic white: 16%; no college degree: 35%; household income <$50,000: 26%). Although all had a biologic sister with breast cancer, 16.5% had average or lower risk of breast cancer according to the Breast Cancer Risk Assessment Tool (Gail score). Most were postmenopausal (66%), parous with a first full-term pregnancy <30y of age (79%), never-smokers (56%) with body mass indexes (BMIs) of <29.9 kg/m2 (70%). Few (5%) reported any cancer prior to enrollment. Conclusions: The Sister Study is a unique cohort designed to efficiently study environmental and genetic risk factors for breast cancer. Extensive exposure data over the life-course and baseline specimens provide important opportunities for studying breast cancer and other health outcomes in women. Collaborations are welcome. https://doi.org/10.1289/EHP1923 PMID:29373861
[Two Dutch sisters in analysis with Freud].
Stroeken, Harry
2010-01-01
The author provides persuasive or at least plausible data for the identity of two patients recorded by Freud in his working season of 1910/11. They were two sisters, living in The Hague/Leiden, who came from a rich banker's family, the van der Lindens. Whereas the treatment does not seem to have led to any decisive improvement for the older of the two, it may have encouraged the younger sister to seek divorce.
ERIC Educational Resources Information Center
Bates, Richard; And Others
Four papers on an ethnographic study of Christian Brothers College (CBC) in Australia, a Catholic college, are presented. In "Christian Brothers College: A View from Overseas," Louis M. Smith discusses research methods, the religious ethos, faculty heterogeneity, diversity in classroom organization, the organizational context of the…
A Unique Case of Allogeneic Fat Grafting Between Brothers
Kim, Samuel; Edelson, Richard L.; Sumpio, Brandon; Kwei, Stephanie
2016-01-01
Summary: We present a case of a 65-year-old man with cutaneous T-cell lymphoma treated with radiation therapy and an allogeneic hematopoietic stem cell transplant from his human leukocyte antigen-matched brother. Engraftment was successful, but the patient went on to develop painful, radiation-induced ulcers. The ulcers were fat-allografted using liposuctioned fat from his brother because of the patient’s unique chimeric state. Postprocedure follow-up revealed epithelialization of the ulcer sites and significant improvement in neuropathic pain. Our unique case study supports the use of fat grafting for its restorative purposes and for its ability to alleviate chronic neuropathic pain. Additionally, it appears that our case provides a basis of a general approach to the treatment of radiation-induced ulcers in chimeric patients with lymphoid malignancies. PMID:27757347
Yamada, S; Yoshimoto, K; Sano, T; Takada, K; Itakura, M; Usui, M; Teramoto, A
1997-01-01
Two of three brothers (the second and third brothers) and their uncle (their mother's brother) presented acrogigantism without multiple endocrine neoplasia type 1 (MEN 1). An invasive macroadenoma was found in the second brother, and it was histologically confirmed as a sparsely granulated GH cell adenoma. Two distinct microadenomas were found in the third brother, and these were histologically diagnosed as a mixed GH cell and PRL cell adenoma and a sparsely granulated GH cell adenoma, respectively. The loss of heterozygosity (LOH) was analyzed in two adenomas (GH cell adenoma from the second brother and a mixed GH cell and PRL cell adenoma from the third brother) by determining microsatellite polymorphisms of DNAs from tumors and patients' leukocytes. The LOH was found on the chromosome 11q13, whereas LOH was not detected on 1p31-36, 2p, 3p, 4, 5, 6p, 7, 8, 9p21-22, 12p, and 19q13 in both pituitary adenomas examined. The haplotype analysis showed that the same haplotype on 11q13 was found in their mother and the unaffected first brother as well as in the affected uncle and two brothers. The deleted alleles on chromosome 11q13 in the tumors of two affected brothers were, however, restricted to those transmitted from their unaffected father. These data suggest that inactivation of the MEN 1 gene or other tumor suppressor genes on chromosome 11q13 plays an important role for the development of our familial acrogigantism without MEN 1.
NASA Astrophysics Data System (ADS)
Barlow, Nadine G.
1995-09-01
If you think Venus is a hellhole now, be thankful you weren't there 500 million years ago. Those were the days, many planetary scientists believe, of apocalypse on our sister world: Volcanoes wracked the land, while greenhouse gases broiled the air. Is this the Earth's fate, too?
Band of Brothers - Warrior Ethos, Unit Effectiveness and the Role of Initial Entry Training
2004-03-19
happy few, we band of brothers; for he today that sheds his blood with me shall be my brother. William Shakespeare Initial Entry Training (IET) in the...the U.S. Army.”52 Unable to strike at the Army, who they felt had forgotten them, the men struck at the inhabitants of Mai Lai 4, a hamlet in the Quang
Brotherly Love? The Manipulation of Body Boundaries
ERIC Educational Resources Information Center
Beck, Benjamin
2011-01-01
This article is about a street-wise boy who is unaware that his younger brother has been using clever manipulation to get him into trouble. Nicholas is a 12-year-old boy whose father was recently given a life sentence for murder. Nicholas is in a boxing league and uses his fighting skills on the streets. Angel is Nicholas' nine-year-old brother…
Rapp, Marion; Spiegler, Juliane; Härtel, Christoph; Gillessen-Kaesbach, Gabrielle; Kaiser, Martin M
2013-01-01
Congenital insensitivity to pain with anhidrosis is an autosomal recessive disorder caused by mutations in the neurotrophic tyrosine receptor kinase 1 (NTRK1) gene, which encodes the receptor for nerve growth factor. We report the clinical and radiological pitfalls in the diagnosis and treatment of two brothers, aged 5 and 8 years, with congenital insensitivity to pain with anhidrosis, the older brother having a proven NTRK1 mutation. In the neonatal period, both presented with recurrent episodes of fever of unknown origin, but their clinical problems changed later. In addition to severe mental retardation and self-harming behaviour, the older brother developed recurrent nonbacterial destructive infections of both the calcaneus and later the talus. No immunodeficiency was found. The younger brother had three complex fractures with a long history of healing problems: overwhelming production of callus, osteomyelitis and movement restrictions. He has less mental retardation than his older brother and shows no self-mutilation.
Replication-Dependent Sister Chromatid Recombination in Rad1 Mutants of Saccharomyces Cerevisiae
Kadyk, L. C.; Hartwell, L. H.
1993-01-01
Homolog recombination and unequal sister chromatid recombination were monitored in rad1-1/rad1-1 diploid yeast cells deficient for excision repair, and in control cells, RAD1/rad1-1, after exposure to UV irradiation. In a rad1-1/rad1-1 diploid, UV irradiation stimulated much more sister chromatid recombination relative to homolog recombination when cells were irradiated in the G(1) or the G(2) phases of the cell cycle than was observed in RAD1/rad1-1 cells. Since sister chromatids are not present during G(1), this result suggested that unexcised lesions can stimulate sister chromatid recombination events during or subsequent to DNA replication. The results of mating rescue experiments suggest that unexcised UV dimers do not stimulate sister chromatid recombination during the G(2) phase, but only when they are present during DNA replication. We propose that there are two types of sister chromatid recombination in yeast. In the first type, unexcised UV dimers and other bulky lesions induce sister chromatid recombination during DNA replication as a mechanism to bypass lesions obstructing the passage of DNA polymerase, and this type is analogous to the type of sister chromatid exchange commonly observed cytologically in mammalian cells. In the second type, strand scissions created by X-irradiation or the excision of damaged bases create recombinogenic sites that result in sister chromatid recombination directly in G(2). Further support for the existence of two types of sister chromatid recombination is the fact that events induced in rad1-1/rad1-1 were due almost entirely to gene conversion, whereas those in RAD1/rad1-1 cells were due to a mixture of gene conversion and reciprocal recombination. PMID:8454200
Sibship size and self-reported inhalant allergy among adult women. ALSPAC Study Team.
Strachan, D P; Harkins, L S; Golding, J
1997-02-01
An association of allergic sensitization with small families and low birth order has been described and attributed to a protective effect of early infection. The influence of like-sex and unlike-sex siblings has not been investigated, although the severity of viral infections may be greater if acquired from unlike-sex siblings. To investigate the association of self-reported inhalant allergy with family composition. Reports of allergy to grass, dust or cats by 11042 pregnant women recruited to a longitudinal study of pregnancy and childhood in Avon, UK, were analysed in relation to respondent's age, maternal age and sibship composition (older and younger brothers and sisters) by multiple logistic regression. The prevalence of self-reported inhalant allergy decreased with increasing numbers of brothers (test for trend: P < 0.0001), but was unrelated to the number of sisters. The unadjusted prevalences for subjects with none, one, two and three or more brothers were 26%, 23%, 20% and 17%, respectively. The corresponding prevalences for numbers of sisters were 23%, 24%, 22% and 23%. After adjustment for total sibship size, offspring of older mothers were more likely to report allergy (test for trend: P < 0.001), but there was no association with position in the sibship. Although it is not possible to determine whether brothers specifically, or unlike-sex siblings in general, are inversely associated with inhalant allergy, these findings are consistent with the hypothesis that patterns of sibling interaction within young families influence the risk of future aeroallergen sensitization.
Two sisters resembling Gorlin-Chaudhry-Moss syndrome.
Aravena, Teresa; Passalacqua, Cristóbal; Pizarro, Oscar; Aracena, Mariana
2011-10-01
The Gorlin-Chaudhry-Moss syndrome (GCMS), was describe initially by Gorlin et al. [Gorlin et al. (1960)] in two sisters with craniosynostosis, hypertrichosis, hypoplastic labia majora, dental defects, eye anomalies, patent ductus arteriosus, and normal intelligence. Two other sporadic instances have been documented. Here, we report on two sisters with a condition with some similarities to GCMS as well as some differences, which could represent either previously unreported variability in GCMS, or it may represent a novel disorder. Copyright © 2011 Wiley-Liss, Inc.
Sister kinetochores are mechanically fused during meiosis I in yeast.
Sarangapani, Krishna K; Duro, Eris; Deng, Yi; Alves, Flavia de Lima; Ye, Qiaozhen; Opoku, Kwaku N; Ceto, Steven; Rappsilber, Juri; Corbett, Kevin D; Biggins, Sue; Marston, Adèle L; Asbury, Charles L
2014-10-10
Production of healthy gametes requires a reductional meiosis I division in which replicated sister chromatids comigrate, rather than separate as in mitosis or meiosis II. Fusion of sister kinetochores during meiosis I may underlie sister chromatid comigration in diverse organisms, but direct evidence for such fusion has been lacking. We used laser trapping and quantitative fluorescence microscopy to study native kinetochore particles isolated from yeast. Meiosis I kinetochores formed stronger attachments and carried more microtubule-binding elements than kinetochores isolated from cells in mitosis or meiosis II. The meiosis I-specific monopolin complex was both necessary and sufficient to drive these modifications. Thus, kinetochore fusion directs sister chromatid comigration, a conserved feature of meiosis that is fundamental to Mendelian inheritance. Copyright © 2014, American Association for the Advancement of Science.
Priests, Brothers, and the Religion and Stress Questionnaire.
ERIC Educational Resources Information Center
Rayburn, Carole A.; And Others
Clergymen have been facing new challenges and stresses resulting from greater numbers of women entering seminaries and positions of religious leadership. In this study, 54 Roman Catholic priests and 50 brothers were given the specially devised Religion and Stress Questionnaire to explore their sensitivity towards some of the gender issues…
Laryngologist Leon Zamenhof--brother of Dr. Esperanto.
Wincewicz, Andrzej; Sulkowska, Mariola; Musiatowicz, Marcin; Sulkowski, Stanislaw
2009-06-01
To reconstruct the biography of the Polish otorhinolaryngologist Leon Zamenhof (1875-1934), a brother of Ludwik Zamenhof, who is famous for invention of the international language Esperanto. Biographical information was collected from pre-World War II resources. Zamenhof developed several important new forms of treatment to help the hearing impaired. Zamenhof was especially interested in the education of deaf children and the therapy necessary to facilitate their integration into society. His significant achievements were a phonetic method of therapy for the hearing impaired and an automatic device for ear insufflation that was considered indispensable in the management of pyorrhea. In addition, Zamenhof initiated various forms of social support among physicians within the medical community of Warsaw, Poland; made health care available to children with hearing impairments; and organized a Jewish school for deaf children. Zamenhof tried to change public attitudes toward deafness, working to promote the integration of the deaf into wider society. He also translated Polish literature into Esperanto. With similar aims to his brother Ludwik, Leon Zamenhof strived to enhance and broaden communication among people who could not hear and to persuade people to change their attitudes about deafness.
Bandak, M; Jørgensen, N; Juul, A; Lauritsen, J; Kier, M G G; Mortensen, M S; Oturai, P S; Mortensen, J; Hojman, P; Helge, J W; Daugaard, G
2017-07-01
Testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to healthy controls. However, because of the fetal etiology of testicular cancer, familial unrelated healthy men might not be an optimal control group. The objective of this study was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39-50) vs. 46 (40-53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7-19). Serum levels of luteinizing hormone and follicle-stimulating hormone were elevated (p ≤ 0.001), while total testosterone, free testosterone, inhibin B and anti-Müllerian hormone were lower (p ≤ 0.001) in testicular cancer survivors than in their biological brothers. The prevalence of metabolic syndrome was similar and apart from HDL-cholesterol, which was lower in testicular cancer survivors (p = 0.01); there were no differences in the individual components of the metabolic syndrome between testicular cancer survivors and their brothers. In conclusion, gonadal function was impaired in testicular cancer survivors, while we did not detect any difference in the prevalence of metabolic syndrome between testicular cancer survivors and their biological brothers. © 2017 American
Sister Mary Emil Penet, I.H.M.: Founder of the Sister Formation Conference
ERIC Educational Resources Information Center
Glisky, Joan
2006-01-01
Mary Emil Penet, I.H.M., (1916-2001) used her talents and charisma to shape the first national organization of American women religious, the Sister Formation Conference (SFC; 1954-1964), facilitating the integrated intellectual, spiritual, psychological, and professional development of vowed women religious. In the decade preceding Vatican II, her…
Digital Data for Volcano Hazards of the Three Sisters Region, Oregon
Schilling, S.P.; Doelger, S.; Scott, W.E.; Iverson, R.M.
2008-01-01
Three Sisters is one of three active volcanic centers that lie close to rapidly growing communities and resort areas in Central Oregon. The major composite volcanoes of this area are clustered near the center of the region and include South Sister, Middle Sister, and Broken Top. Additionally, hundreds of mafic volcanoes are scattered throughout the Three Sisters area. These range from small cinder cones to large shield volcanoes like North Sister and Belknap Crater. Hazardous events include landslides from the steep flanks of large volcanoes and floods, which need not be triggered by eruptions, as well as eruption-triggered events such as fallout of tephra (volcanic ash) and lava flows. A proximal hazard zone roughly 20 kilometers (12 miles) in diameter surrounding the Three Sisters and Broken Top could be affected within minutes of the onset of an eruption or large landslide. Distal hazard zones that follow river valleys downstream from the Three Sisters and Broken Top could be inundated by lahars (rapid flows of water-laden rock and mud) generated either by melting of snow and ice during eruptions or by large landslides. Slow-moving lava flows could issue from new mafic volcanoes almost anywhere within the region. Fallout of tephra from eruption clouds can affect areas hundreds of kilometers (miles) downwind, so eruptions at volcanoes elsewhere in the Cascade Range also contribute to volcano hazards in Central Oregon. Scientists at the Cascades Volcano Observatory created a geographic information system (GIS) data set which depicts proximal and distal lahar hazard zones as well as a regional lava flow hazard zone for Three Sisters (USGS Open-File Report 99-437, Scott and others, 1999). The various distal lahar zones were constructed from LaharZ software using 20, 100, and 500 million cubic meter input flow volumes. Additionally, scientists used the depositional history of past events in the Three Sisters Region as well as experience and judgment derived from the
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-02
... Landfill Fire Superfund Site; Ashland, Boyd County, KY; Notice of Settlement AGENCY: Environmental... Brothers Landfill Fire Superfund Site located in Ashland, Boyd County, Kentucky for publication. DATES: The..., identified by Docket ID No. EPA-RO4- SFUND-2010- 0447 or Site name Cooksey Brothers Landfill Superfund Site...
Neuropsychological profiles of three sisters homozygous for the fragile X premutation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mazzocco, M.M.M.; Holden, J.J.A.
1996-08-09
Fragile X syndrome (fraX) is associated with an amplification of a CGG repeat within the fraX mental retardation (FMR-1) gene. We describe an exceptional family in which 3 adult sisters are homozygous for the FMR-1 premutation. Each sister inherited 2 premutation alleles (ca. 80 CGG repeats) from their biologically unrelated parents. The 3 sisters were administered measures of executive function, visual spatial, memory, and verbal skills. Deficiencies in the first 2 of these domains have been reported among females with the full mutation. The sisters` performances were compared with available normative data and with published group means for females affectedmore » by fraX. These women did not appear to have verbal or memory difficulties. None of the women demonstrated a global executive function deficit, and none had global deficits in spatial ability. The profiles of these sisters are consistent with reports that the fragile X premutation does not affect cognitive performance. 31 refs., 1 fig., 4 tabs.« less
Female-patterned alopecia in teenage brothers with unusual histologic features.
Carlson, J Andrew; Malysz, Jozef; Schwartz, Joseph
2006-11-01
Patterned hair loss, follicular miniaturization, and increased telogen hair counts characterize androgenic alopecia (AGA). Follicular inflammation in AGA has been associated with treatment resistance and progressive hair loss. Brothers, 15 and 18 years old, presented with frontal and mid-scalp hair loss with an intact frontal hairline noted over a 1-year period. The elder reported past use of androgenic steroids. Laboratory assessment for metabolic and hormonal abnormalities was unrevealing, and hair pull test was negative. Scalp biopsies revealed decreased terminal hairs, marked diameter variation of anagen hairs, decreased terminal to vellus hair ratios (3.7:1/3.4:1, older/younger), and increased telogen counts (23%/21%). Infrabulbar and peri-isthmic (follicular bulge region) lymphocytic infiltrates were present. Hair loss has progressed, unabated by daily topical 0.5% clobetasol (for 6 months), daily 5% minoxidil (1 year), and latter, daily oral finasteride (2 years - older brother only). Based on patterned hair loss and miniaturized hairs, these brothers have AGA. The female pattern of hair loss (diffuse hair loss affecting the central scalp with preservation of frontal hair line) coupled with follicular isthmic lymphocytic inflammation represents an unusual presentation, possibly a treatment resistant, inflammatory variant of AGA. The differential diagnosis includes exogenous androgen-mediated hair loss, cicatricial pattern hair loss, or the superimposition of alopecia areata.
Splitting the chromosome: cutting the ties that bind sister chromatids.
Nasmyth, K; Peters, J M; Uhlmann, F
2001-01-01
In eukaryotic cells, replicated DNA molecules remain physically connected from their synthesis in S phase until they are separated during anaphase. This phenomenon, called sister chromatid cohesion, is essential for the temporal separation of DNA replication and mitosis and for the equal separation of the duplicated genome. Recent work has identified a number of chromosomal proteins required for cohesion. In this review we discuss how these proteins may connect sister chromatids and how they are removed from chromosomes to allow sister chromatid separation at the onset of anaphase.
Sibling Relationships: Parent-Child Agreement and Contributions of Siblings With and Without ASD.
Braconnier, Megan L; Coffman, Marika C; Kelso, Nicole; Wolf, Julie M
2018-05-01
Research on the experiences of siblings of individuals with ASD and the quality of their sibling relationships has yielded mixed results. The present study examined the significance of parent- versus child-report of both positive and negative behaviors exhibited by siblings and their brothers and sisters with ASD within sibling dyads. Findings indicated that siblings were more positive in their assessment of the sibling relationship than were their parents. Siblings exhibited more positive behaviors within the sibling relationship than did their brothers and sisters with ASD, and were recipients of aggression. These findings are consistent with prior research suggesting that siblings tend to take on a caretaking role, and point to important targets for intervention.
Seltzer, Marsha Mailick
2010-01-01
The purpose of this study was to test a diathesis-stress model of well-being for siblings who have a brother or sister with an autism spectrum disorder (ASD). Data were collected from 57 adolescents and their mothers. Sisters reported higher levels of depressive and anxiety symptoms than brothers. Having a family history of ASDs was associated with depressive, but not anxiety, symptoms. A high level of maternal depression was also associated with more depressive and anxiety symptoms. A diathesis-stress model was partially supported, primarily through the findings that sibling sub-threshold autism characteristics were associated with depressive and anxiety symptoms in siblings, but only in the presence of a high number of stressful life events. PMID:19291379
Life Events, Genetic Susceptibility, and Smoking among Adolescents
Pampel, Fred C.; Boardman, Jason D.; Daw, Jonathan; Stallings, Michael C.; Smolen, Andrew; Haberstick, Brett; Widaman, Keith F.; Neppl, Tricia K.; Conger, Rand D.
2015-01-01
Although stressful life events during adolescence are associated with the adoption of unhealthy behaviors such as smoking, both social circumstances and physical traits can moderate the relationship. This study builds on the stress paradigm and gene-environment approach to social behavior by examining how a polymorphism in the serotonin transporter gene 5-HTTLPR moderates the effect of life events on adolescent smoking. Tests of interaction hypotheses use data from the Family Transitions Project, a longitudinal study of 7th graders followed for 5 years. A sibling-pair design with separate models for the gender composition of pairs (brothers, sisters, or brother/sister) controls for unmeasured family background. The results show that negative life events are significantly and positively associated with smoking. Among brother pairs but not other pairs, the results provide evidence of gene-environment interaction by showing that life events more strongly influence smoking behavior for those with more copies of the 5-HTTLPR S allele. PMID:26463545
Generativity in Elderly Oblate Sisters of Providence.
Black, Helen K; Hannum, Susan M; Rubinstein, Robert L; de Medeiros, Kate
2016-06-01
We explored how generativity and well-being merged in a group of childless older women: African and Hispanic Roman Catholic Religious Sisters, linking two minority identity characteristics. We qualitatively interviewed 8 Oblate Sisters of Providence (OSP), by providing a framework for examining the range of the women's generativity-cultural spheres in which generativity is rooted and outlets for generativity. Early negative experiences, such as fleeing despotism in Haiti and Cuba and racism within the Catholic Church, occurred alongside positive experiences-families who stressed education, and Caucasian Religious who taught children of color. This became a foundation for the Sister's generative commitment. Findings highlight that research gains from a phenomenological understanding of how religious faith promotes generative cognitions and emotions. Findings also reveal that the experiences of a subculture in society-African-American elderly women religious-add to theories and definitions of generativity. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
"Our Boys": The Christian Brothers and the Formation of Youth in the "New Ireland"1914-1944
ERIC Educational Resources Information Center
Keogh, Daire
2015-01-01
This essay investigates the development of the boys' magazine, "Our Boys," and how this became a powerful auxiliary to the Christian Brothers' work in schools. It championed the values that the Christian Brothers had propagated since their foundation in 1802. Often characterised as Celtic and Romantic, it was neither, but aimed at…
GNE Myopathy in Turkish Sisters with a Novel Homozygous Mutation
Diniz, Gulden; Secil, Yaprak; Ceylaner, Serdar; Tokucoglu, Figen; Türe, Sabiha; Celebisoy, Mehmet; İncesu, Tülay Kurt; Akhan, Galip
2016-01-01
Background. Hereditary inclusion body myopathy is caused by biallelic defects in the GNE gene located on chromosome 9p13. It generally affects adults older than 20 years of age. Methods and Results. In this study, we present two Turkish sisters with progressive myopathy and describe a novel mutation in the GNE gene. Both sisters had slightly higher levels of creatine kinase (CK) and muscle weakness. The older sister presented at 38 years of age with an inability to climb steps, weakness, and a steppage gait. Her younger sister was 36 years old and had similar symptoms. The first symptoms of the disorder were seen when the sisters were 30 and 34 years old, respectively. The muscle biopsy showed primary myopathic features and presence of rimmed vacuoles. DNA analysis demonstrated the presence of previously unknown homozygous mutations [c.2152 G>A (p.A718T)] in the GNE genes. Conclusion. Based on our literature survey, we believe that ours is the first confirmed case of primary GNE myopathy with a novel missense mutation in Turkey. These patients illustrate that the muscle biopsy is still an important method for the differential diagnosis of vacuolar myopathies in that the detection of inclusions is required for the definitive diagnosis. PMID:27298745
20 CFR 725.101 - Definition and use of terms.
Code of Federal Regulations, 2012 CFR
2012-04-01
... any surviving spouse, divorced spouse, child, parent, brother or sister, who is entitled to benefits...) Person means an individual, partnership, association, corporation, firm, subsidiary or parent of a...
The determination of the tribe of family members in Luhak Limopuluh Koto, West Sumatera Indonesia
NASA Astrophysics Data System (ADS)
Bahri, S.; Abbas, A.; Bakar, N. N.
2018-01-01
In this paper, some mathematical models that state the tribe of the family members in Nagari Luhak Limopuluh Koto West Sumatera, Indonesia were built. The models were constructed by using the marriage rule and the ethnic data of Minangkabau community which embrace the matrilineal system. The marriage rule prohibits the same inter-tribal marriage while the matrilineal system causes the mother, child, and sibling tribes to be equal. Therefore, the matrices formed by marriage rule, mother-son tribal relation, someone-his/her sibling tribal relation, and the transpose of the matrices, are used in matrix multiplication to obtain the tribal models. The models are consecutively A, AC’, (AC’)B, ((AC’)B)W’, ((AC’)B)C, ((AC’)B)W, ((AC’)W’ for Denai, Denai’s mother, the sister of Denai’s mother, the brother of Denai’s mother, the husband of Denai’s mother’s sister, the son of Denai’s mother’s sister, the wife of Denai’s mother’s brother, and the Denai’s father models.
Correlation of WAIS IQ in 10 Pairs of Brothers.
ERIC Educational Resources Information Center
Matarazzo, Joseph D.; And Others
1978-01-01
Pairs of brothers were individually examined with Wechsler Adult Intelligence Scale some 10 months apart by an experienced clinical psychologist unaware of the consanguineous relationship. Correlation of .42 for Full Scale IQ is consistent with median correlation reported by Erlenmeyer-Kimling and Jarvik in their 1963 literature review.…
Code of Federal Regulations, 2013 CFR
2013-01-01
... marriage, or within the same household, such as a spouse, parent, child, brother, sister, aunt, uncle..., liability, property damage, flood or mudslide, worker's compensation, fidelity bond, malpractice, or any...
Code of Federal Regulations, 2014 CFR
2014-01-01
... marriage, or within the same household, such as a spouse, parent, child, brother, sister, aunt, uncle..., liability, property damage, flood or mudslide, worker's compensation, fidelity bond, malpractice, or any...
Code of Federal Regulations, 2011 CFR
2011-01-01
... marriage, or within the same household, such as a spouse, parent, child, brother, sister, aunt, uncle..., liability, property damage, flood or mudslide, worker's compensation, fidelity bond, malpractice, or any...
13 CFR 127.102 - What are the definitions of the terms used in this part?
Code of Federal Regulations, 2011 CFR
2011-01-01
... EDWOSBs. Immediate family member means father, mother, husband, wife, son, daughter, brother, sister, grandfather, grandmother, grandson, granddaughter, father-in-law, mother-in-law, son-in-law, and daughter-in...
20 CFR 725.101 - Definition and use of terms.
Code of Federal Regulations, 2013 CFR
2013-04-01
... any surviving spouse, divorced spouse, child, parent, brother or sister, who is entitled to benefits..., partnership, association, corporation, firm, subsidiary or parent of a corporation, or other organization or...
Burden of Common Complex Disease Variants in the Exomes of Two Healthy Centenarian Brothers.
Tindale, Lauren C; Zeng, Andy; Bretherick, Karla L; Leach, Stephen; Thiessen, Nina; Brooks-Wilson, Angela R
2015-01-01
It is not understood whether long-term good health is promoted by the absence of disease risk variants, the presence of protective variants, or both. We characterized the exomes of two exceptionally healthy centenarian brothers aged 106 and 109 years who had never been diagnosed with cancer, cardiovascular disease, diabetes, Alzheimer's disease, or major pulmonary disease. The aim of this study was to gain insight into whether exceptional health and longevity are a result of carrying fewer disease-associated variants than typical individuals. We compared the number of disease-associated alleles, and the proportion of alleles predicted to be functionally damaging, between the centenarian brothers and published population data. Mitochondrial sequence reads were extracted from the exome data in order to analyze mitochondrial variants. The brothers carry a similar number of common disease-associated variants and predicted damaging variants compared to reference groups. They did not carry any high-penetrance clinically actionable variants. They carry mitochondrial haplogroup T, and one brother has a single heteroplasmic variant. Although our small sample size does not allow for definitive conclusions, a healthy aging and longevity phenotype is not necessarily due to a decreased burden of common disease-associated variants. Instead, it may be rare 'positive' variants that play a role in this desirable phenotype. © 2015 S. Karger AG, Basel.
Mechanics of Sister Chromatids studied with a Polymer Model
NASA Astrophysics Data System (ADS)
Zhang, Yang; Isbaner, Sebastian; Heermann, Dieter
2013-10-01
Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells. Cohesion is mediated by binding proteins and only resolved after mitotic chromosome condensation is completed. However, the amount of attachement points required to maintain sister chromatid cohesion while still allowing proper chromosome condensation is not known yet. Additionally the impact of cohesion on the mechanical properties of chromosomes also poses an interesting problem. In this work we study the conformational and mechanical properties of sister chromatids by means of computer simulations. We model both protein-mediated cohesion between sister chromatids and chromosome condensation with a dynamic binding mechanisms. We show in a phase diagram that only specific link concentrations lead to connected and fully condensed chromatids that do not intermingle with each other nor separate due to entropic forces. Furthermore we show that dynamic bonding between chromatids decrease the Young's modulus compared to non-bonded chromatids.
Geologic map of Three Sisters volcanic cluster, Cascade Range, Oregon
Hildreth, Wes; Fierstein, Judy; Calvert, Andrew T.
2012-01-01
The cluster of glaciated stratovolcanoes called the Three Sisters—South Sister, Middle Sister, and North Sister—forms a spectacular 20-km-long reach along the crest of the Cascade Range in Oregon. The three eponymous stratocones, though contiguous and conventionally lumped sororally, could hardly display less family resemblance. North Sister (10,085 ft), a monotonously mafic edifice at least as old as 120 ka, is a glacially ravaged stratocone that consists of hundreds of thin rubbly lava flows and intercalated falls that dip radially and steeply; remnants of two thick lava flows cap its summit. Middle Sister (10,047 ft), an andesite-basalt-dacite cone built between 48 and 14 ka, is capped by a thick stack of radially dipping, dark-gray, thin mafic lava flows; asymmetrically glaciated, its nearly intact west flank contrasts sharply with its steep east face. Snow and ice-filled South Sister is a bimodal rhyolitic-intermediate edifice that was constructed between 50 ka and 2 ka; its crater (rim at 10,358 ft) was created between 30 and 22 ka, during the most recent of several explosive summit eruptions; the thin oxidized agglutinate that mantles its current crater rim protects a 150-m-thick pyroclastic sequence that helped fill a much larger crater. For each of the three, the eruptive volume is likely to have been in the range of 15 to 25 km³, but such estimates are fairly uncertain, owing to glacial erosion. The map area consists exclusively of Quaternary volcanic rocks and derivative surficial deposits. Although most of the area has been modified by glaciation, the volcanoes are young enough that the landforms remain largely constructional. Furthermore, twelve of the 145 eruptive units on the map are postglacial, younger than the deglaciation that was underway by about 17 ka. The most recent eruptions were of rhyolite near South Sister, about 2,000 years ago, and of mafic magma near McKenzie Pass, about 1,500 years ago. As observed by trailblazing volcanologist
Taylor, Julie Lounds; Shivers, Carolyn M.
2013-01-01
This study examined aspects of the sibling relationship that predicted altruistic behaviors in siblings of individuals with mild intellectual deficits at three time points in adulthood: in their mid 30s, early 50s, and mid 60s. We identified 393 such siblings from the Wisconsin Longitudinal Study, a prospective longitudinal study that followed participants from ages 18 to 64. Being an only sibling, being older than the brother or sister with mild intellectual deficits, as well as having more contact with and feeling closer to the brother or sister predicted more altruistic behavior in adulthood for female siblings, but not for males. Earlier measures of contact and closeness between siblings were better indicators of altruistic behaviors than concurrent measures. PMID:21740255
Otsuka, Hiroki; Sasai, Hideo; Abdelkreem, Elsayed; Kawamoto, Norio; Kawamoto, Minako; Kamiya, Toshiya; Tanimoto, Yasuo; Kikuchi, Atsuo; Kure, Shigeo; Numakura, Chikahiko; Hayasaka, Kiyoshi; Fukao, Toshiyuki
2016-12-01
Citrin deficiency, an inherited defect of the liver-type mitochondrial aspartate/glutamate carrier isoform (citrin), may cause impairment of glycolysis because of an increase in the cytosolic NADH/NAD + ratio. We report a Japanese boy whose main complaint was recurrent hypoglycemic episodes. He was suspected as having citrin deficiency because of his peculiar preference for protein- and fat-rich food. His young sister also had a similar food preference. Both siblings were diagnosed with citrin deficiency by genetic analysis. The brother and sister underwent an oral glucose tolerance test (OGTT) at 10 and 7 yr of age, respectively. Blood glucose, ammonia, lactic acid, pyruvic acid, and insulin levels were monitored before starting the test, and then every 30 min. During this test, they maintained blood glucose levels until 180 min. At 210 min, they experienced vomiting, feeling ill, and decreased blood glucose levels (2.9 and 2.8 mmol/l in the brother and sister, respectively). The sister and brother recovered uneventfully by intravenous glucose injection. In a second OGTT, 4 months after medium-chain triglyceride (MCT) oil supplementation, they had no major symptoms and normal glucose levels were maintained, even after 240 min. Additionally, after MCT oil therapy, their food preference slightly changed as they started eating more carbohydrates. Our OGTT data suggest excess carbohydrate intake has adverse consequences in patients with citrin deficiency, including hypoglycemia after a few hours. MCT oil therapy may be effective in preventing such hypoglycemia and improving metabolic derangement, even during the so-called apparently healthy period.
High Functioning Autism and Childhood Disintegrative Disorder in Half Brothers.
ERIC Educational Resources Information Center
Zwaigenbaum, L.; Szatmari, P.; Mahoney, W.; Bryson, S.; Bartolucci, G.; MacLean, J.
2000-01-01
This case report describes the presence of autism and Childhood Disintegrative Disorder (CDD) cosegregating within a sibship of half-brothers with the same mother. The report suggests that the rarity of the two conditions suggests a shared transmissible mechanism. (Contains references.) (Author/DB)
Sister Circles as a Culturally Relevant Intervention for Anxious African American Women
Neal-Barnett, Angela; Stadulis, Robert; Murray, Marsheena; Payne, Margaret Ralston; Thomas, Anisha; Salley, Bernadette B.
2011-01-01
Research on anxiety treatment with African American women reveals a need to develop interventions that address factors relevant to their lives. Such factors include feelings of isolation, multiple roles undertaken by Black women, and faith. A recurrent theme across treatment studies is the importance of having support from other Black women. Sister circles are support groups that build upon existing friendships, fictive kin networks, and the sense of community found among African Americans females. Sister circles appear to offer many of the components Black women desire in an anxiety intervention. In this article, we explore sister circles as an intervention for anxious African American women. Culturally-infused aspects from our sister circle work with middle-class African American women are presented. Further research is needed. PMID:22081747
Women in-between' (Strathern, 1995): the ambiguous position of the sister tutor, 1918-1960.
Brooks, Jane
2007-02-01
The purpose of this article is to explore the ambiguous position of sister tutors, within the nursing and hospital hierarchy between 1918 and 1960. The function of the sister tutor was to train the probationers (student nurses). However, I will argue that the students' education was to come second to the service needs of the hospital, the authority of the matron and desire of the medical profession to maintain control over the nursing curriculum and nursing practice. Therefore sister tutors were caught 'in-between' several opposing forces which together militated against the individual sister tutor's work and the ability of the nursing profession to recruit adequate numbers of senior nurses into the classroom. The recruitment issue was further hampered by the widespread knowledge that much of the sister tutor's work was not student education at all, but organising lectures by medical staff and marking students' notes. In order to gauge the 'official' attitudes to the sister tutors and also the experiences of those who either worked as sister tutors or were taught by them, I used both archival and oral evidence in the research for this article. Pseudonyms have been used throughout for the oral history respondents.
The Seven Sisters Pose for Spitzer
2007-04-16
The Seven Sisters, also known as the Pleiades star cluster, seem to float on a bed of feathers in a new infrared image from NASA Spitzer Space Telescope. Clouds of dust sweep around the stars, swaddling them in a cushiony veil.
Pereira, Sara; Todd Katzmarzyk, Peter; Gomes, Thayse Natacha; Souza, Michele; Chaves, Raquel Nichele; dos Santos, Fernanda Karina; Santos, Daniel; Hedeker, Donald; Maia, José
2017-01-01
This study investigates biological, behavioural and sociodemographic correlates of intra-pair similarities, and estimates sibling resemblance in health-related physical fitness (PF). The sample comprises 1101 biological siblings (525 females) aged 9–20 years. PF components and markers were: morphological [waist circumference (WC) and %body fat (%BF)], muscular [handgrip strength (GS) and standing long jump (SLJ)], motor [50-yard dash (50YD) and shuttle run (SR)], and cardiorespiratory (1-mile run). Biological maturation was assessed; physical activity (PA), TV viewing and socioeconomic status (SES) information was obtained. On average, older and more mature subjects are better performers in all PF components; PA was negatively associated with SR, while SES was negatively associated with SLJ and SR. A pattern was observed in the intraclass correlations (ρ) wherein same sex siblings demonstrate greater resemblance for most PF components (sister-sister: 0.35≤ ρ≤0.55; brother-brother: (0.25≤ρ≤0.60) than brother-sister pairs (BS) (0≤ρ≤0.15), except for %BF (ρBB>ρSS>ρBS), and the 1-mile run (ρSS>ρBS>ρBB). In conclusion, behavioural and sociodemographic correlates play different roles in siblings PF expression. Further, a significant familial PF resemblance was observed with different trends in different sibling types, probably due to variations in shared genetic factors and sociodemographic conditions. PMID:28187195
Cut2 proteolysis required for sister-chromatid seperation in fission yeast.
Funabiki, H; Yamano, H; Kumada, K; Nagao, K; Hunt, T; Yanagida, M
1996-05-30
Although mitotic cyclins are well-known substrates for ubiquitin-mediated proteolysis at the metaphase-anaphase transition, their degradation is not essential for separation of sister chromatids; several lines of evidence suggest that proteolysis of other protein(s) is required, however. Here we report the anaphase-specific proteolysis of the Schizosaccharomyces pombe Cut2 protein, which is essential for sister-chromatid separation. Cut2 is located in the nucleus, where it is concentrated along the short metaphase spindle. The rapid degradation of Cut2 at anaphase requires its amino-terminal region and the activity of Cut9 (ref. 14), a component of the 20S cyclosome/anaphase-promoting complex (APC), which is necessary for cyclin destruction. Expression of non-degradable Cut2 blocks sister-chromatid separation but not cell-cycle progression. This defect can be overcome by grafting the N terminus of cyclin B onto the truncated Cut2, demonstrating that the regulated proteolysis of Cut2 is essential for sister-chromatid separation.
[Florence Nightingale and charity sisters: revisiting the history].
Padilha, Maria Itayra Coelho de Souza; Mancia, Joel Rolim
2005-01-01
This study presents an historical analysis on the links between the nursing practice and the influence received from various religious orders/associations along the times, especially from Saint Vincent Paul's charity sisters. The professional nursing which was pioneered by Florence Nightingale in the XlXth century, was directly influenced by the teachings of love and fraternity. In addition, other contributions from the religious orders/associations were the concepts of altruism, valorization of an adequate environment for the care of patients, and the division of work in nursing. The study shows the influence of Charity Sisters on Florence Nightingale.
38 CFR 36.4352 - Authority to close loans on the automatic basis.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (e.g., spouse, parent, grandparent, child, brother, sister, aunt, uncle or in-law) has a financial... indicate that it will not seek to influence the lender to give their loans more favorable underwriting...
38 CFR 36.4352 - Authority to close loans on the automatic basis.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (e.g., spouse, parent, grandparent, child, brother, sister, aunt, uncle or in-law) has a financial... indicate that it will not seek to influence the lender to give their loans more favorable underwriting...
38 CFR 36.4352 - Authority to close loans on the automatic basis.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (e.g., spouse, parent, grandparent, child, brother, sister, aunt, uncle or in-law) has a financial... indicate that it will not seek to influence the lender to give their loans more favorable underwriting...
Varicella (Chickenpox) Vaccine
ProQuad® (as a combination product containing Measles Vaccine, Mumps Vaccine, Rubella Vaccine, Varicella Vaccine) ... Has a parent, brother, or sister with a history of immune system problems. Is taking salicylates (such ...
Siblings of Oedipus: Brothers and Sisters of Incest Victims.
ERIC Educational Resources Information Center
de Young, Mary
1981-01-01
Investigates the roles and problems of siblings of incest victims, describes the dynamics of the incestuous family, and identifies some behavior problems of children whose siblings were incest victims. Data from two siblings' lives are presented to illustrate points. (Author/DB)
Babbitt's Brothers & Sisters: Raising Ethical Issues in Business Literature.
ERIC Educational Resources Information Center
Halpern, Jeanne W.
A college-level course in business literature is an ideal place to raise and discuss ethical issues. To be successful, a teacher of this course must engage student interest, help the students articulate and understand their own ethical attitudes, clarify the stance and artistry of the author, and refine student responses to ethical questions. When…
... is an autoimmune disease, meaning the body's immune (defense) system attacks and destroys the cells in the ... Age: It often develops in childhood. Family health history: Having a parent or brother or sister with ...
20 CFR 222.41 - Determination of relationship and support for parent.
Code of Federal Regulations, 2013 CFR
2013-04-01
... RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.41... adoptive parent before the employee became 16 years old (the marriage must be valid under the law of the...
20 CFR 222.41 - Determination of relationship and support for parent.
Code of Federal Regulations, 2014 CFR
2014-04-01
... RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.41... adoptive parent before the employee became 16 years old (the marriage must be valid under the law of the...
20 CFR 222.41 - Determination of relationship and support for parent.
Code of Federal Regulations, 2012 CFR
2012-04-01
... RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.41... adoptive parent before the employee became 16 years old (the marriage must be valid under the law of the...
29 CFR 15.200 - What is a claim under the MPCECA and who may file such a claim?
Code of Federal Regulations, 2013 CFR
2013-07-01
... claim under the MPCECA for damage or loss is allowable only if the property involved was being used..., children, parent, brother or sister or the authorized agent or legal representative of such person or...
29 CFR 15.200 - What is a claim under the MPCECA and who may file such a claim?
Code of Federal Regulations, 2014 CFR
2014-07-01
... claim under the MPCECA for damage or loss is allowable only if the property involved was being used..., children, parent, brother or sister or the authorized agent or legal representative of such person or...
32 CFR 553.17 - Persons ineligible for burial in an Army national cemetery.
Code of Federal Regulations, 2010 CFR
2010-07-01
... burial in an Army national cemetery. (a) A father, mother, brother, sister, and in-law is not eligible... for burial in Arlington National Cemetery unless the Service-connected family member has been or will...
Code of Federal Regulations, 2014 CFR
2014-07-01
... the state where the autopsy will be performed, consists of a number of persons such as children, parents, brothers and sisters, etc., permission to perform an autopsy may be accepted when granted by the...
On PMWs and two-stroke engines.
Bell, W.; Yassi, A.; Cole, D. C.
1998-01-01
On Saturday, August 24, 1996, a 40-year-old man from Edmonton was riding a personal motorized watercraft (PMW, a Seadoo or Jet Ski type of machine) on Shuswap Lake, in south-central British Columbia. He was approximately 200 m offshore. The man motioned to his sister, who was riding another PMW, to follow him across the lake. She did so, but as the turned her head to check for other boat traffic, her brother suddenly slowed down and her machine rode right up on his back, crushing him against his handlebars. His sister, a nurse, held her brother's head above water until help arrived but, 48 minutes after the moment of impact, he was pronounced dead at the Shuswap Lake General Hospital. He had suffered a ruptured aorta. PMID:9789655
Craine, Jessica L.; Tanaka, Teri A.; Nishina, Adrienne; Conger, Katherine J.
2009-01-01
The present study examined delinquency concordance and the moderating effects of younger sibling perceptions of older sibling popularity in a sample of 587 adolescent sibling pairs. Using a social learning framework, and taking dyad composition into account, perceptions of popularity were hypothesized to strengthen siblings’ concordance for delinquency. Older sibling delinquency significantly predicted younger sibling delinquency. Older sibling popularity was not important in predicting boys’ delinquency. However, perceptions of older sibling popularity directly predicted reduced delinquency for girls with older sisters. A significant interaction effect was found for girls with older brothers. Older brother delinquency predicted girls’ delinquency for girls who perceived their older brother to be relatively popular. There was no delinquency concordance for girls who perceived their older brothers to be less popular. PMID:20305731
Naseer, Muhammad Imran; Sogaty, Sameera; Rasool, Mahmood; Chaudhary, Adeel G; Abutalib, Yousif Ahmed; Walker, Susan; Marshall, Christian R; Merico, Daniele; Carter, Melissa T; Scherer, Stephen W; Al-Qahtani, Mohammad H; Zarrei, Mehdi
2016-11-01
We describe two brothers from a consanguineous family of Egyptian ancestry, presenting with microcephaly, apparent global developmental delay, seizures, spasticity, congenital blindness, and multiple cutaneous capillary malformations. Through exome sequencing, we uncovered a homozygous missense variant in STAMBP (p.K303R) in the two siblings, inherited from heterozygous carrier parents. Mutations in STAMBP are known to cause microcephaly-capillary malformation syndrome (MIC-CAP) and the phenotype in this family is consistent with this diagnosis. We compared the findings in the present brothers with those of earlier reported patients. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-07
...: The proposed Three Sisters Irrigation District Hydroelectric Project would be located on the north pipe of the Three Sisters Irrigation District's Main Canal Pipeline in Deschutes County, Oregon. The... of Project: The Three Sisters Irrigation District Hydroelectric Project would consist of: (1) An...
Code of Federal Regulations, 2010 CFR
2010-04-01
... the donor's family include only his brothers and sisters (whether by whole or half blood), spouse... which a prohibited transaction occurred, or in a prior taxable year, unless the donor or a member of his...
Code of Federal Regulations, 2012 CFR
2012-04-01
... in Example (5) except that, in addition, on November 1, 1970, D donates 2 percent of the outstanding... brothers and sisters (whether by the whole or half blood), his spouse, his ancestors, and his lineal...
Code of Federal Regulations, 2013 CFR
2013-04-01
... in Example (5) except that, in addition, on November 1, 1970, D donates 2 percent of the outstanding... brothers and sisters (whether by the whole or half blood), his spouse, his ancestors, and his lineal...
Code of Federal Regulations, 2011 CFR
2011-04-01
... in Example (5) except that, in addition, on November 1, 1970, D donates 2 percent of the outstanding... brothers and sisters (whether by the whole or half blood), his spouse, his ancestors, and his lineal...
Brotherly Advice: Letters from Hugo to Paul Ehrenfest in his Final Years
NASA Astrophysics Data System (ADS)
Halpern, Paul
2006-03-01
At the start of the 1930s, theoretician Paul Ehrenfest spent much of his time traveling through America and Europe while engaged in a steady stream of lectures. This traveling phase coincided with a frantic and intense period of negative self-examination, financial difficulty, and various other personal concerns that would ultimately lead to his 1933 suicide. Throughout these final years, he kept up a steady correspondence with his brother Hugo, a physician based in Saint Louis. Ten years older than Paul, Hugo freely doled out frank psychological advice about subjects ranging from the proper treatment of children to the dangers of self-pity. Through a look at some of the letters exchanged between the two brothers, this talk will examine the role Hugo played during the dark final years of Paul Ehrenfest's life.
Gene-culture translation in the avoidance of sibling incest
Lumsden, Charles J.; Wilson, Edward O.
1980-01-01
A preliminary analysis is made of the relation between the epigenetic rules of brother-sister incest avoidance, which operate during individual development, and the frequency of occurrence of this form of incest among cultures. PMID:16592898
... if your father or a brother was diagnosed with heart disease before 55 years of age, or if your mother or a sister was diagnosed with heart disease before 65 years of age. Preeclampsia (pre-e- ...
... if your father or a brother was diagnosed with heart disease before 55 years of age, or if your mother or a sister was diagnosed with heart disease before 65 years of age. Preeclampsia (pre-e- ...
42 CFR 51c.304 - Governing board.
Code of Federal Regulations, 2012 CFR
2012-10-01
... of demographic factors, such as race, ethnicity, sex. (2) No more than one-half of the remaining... employee of the center, or spouse or child, parent, brother or sister by blood or marriage of such an...
42 CFR 51c.304 - Governing board.
Code of Federal Regulations, 2011 CFR
2011-10-01
... of demographic factors, such as race, ethnicity, sex. (2) No more than one-half of the remaining... employee of the center, or spouse or child, parent, brother or sister by blood or marriage of such an...
42 CFR 51c.304 - Governing board.
Code of Federal Regulations, 2013 CFR
2013-10-01
... of demographic factors, such as race, ethnicity, sex. (2) No more than one-half of the remaining... employee of the center, or spouse or child, parent, brother or sister by blood or marriage of such an...
42 CFR 51c.304 - Governing board.
Code of Federal Regulations, 2014 CFR
2014-10-01
... of demographic factors, such as race, ethnicity, sex. (2) No more than one-half of the remaining... employee of the center, or spouse or child, parent, brother or sister by blood or marriage of such an...
Sisters Unbound Is Required for Meiotic Centromeric Cohesion in Drosophila melanogaster
Krishnan, Badri; Thomas, Sharon E.; Yan, Rihui; Yamada, Hirotsugu; Zhulin, Igor B.; McKee, Bruce D.
2014-01-01
Regular meiotic chromosome segregation requires sister centromeres to mono-orient (orient to the same pole) during the first meiotic division (meiosis I) when homologous chromosomes segregate, and to bi-orient (orient to opposite poles) during the second meiotic division (meiosis II) when sister chromatids segregate. Both orientation patterns require cohesion between sister centromeres, which is established during meiotic DNA replication and persists until anaphase of meiosis II. Meiotic cohesion is mediated by a conserved four-protein complex called cohesin that includes two structural maintenance of chromosomes (SMC) subunits (SMC1 and SMC3) and two non-SMC subunits. In Drosophila melanogaster, however, the meiotic cohesion apparatus has not been fully characterized and the non-SMC subunits have not been identified. We have identified a novel Drosophila gene called sisters unbound (sunn), which is required for stable sister chromatid cohesion throughout meiosis. sunn mutations disrupt centromere cohesion during prophase I and cause high frequencies of non-disjunction (NDJ) at both meiotic divisions in both sexes. SUNN co-localizes at centromeres with the cohesion proteins SMC1 and SOLO in both sexes and is necessary for the recruitment of both proteins to centromeres. Although SUNN lacks sequence homology to cohesins, bioinformatic analysis indicates that SUNN may be a structural homolog of the non-SMC cohesin subunit stromalin (SA), suggesting that SUNN may serve as a meiosis-specific cohesin subunit. In conclusion, our data show that SUNN is an essential meiosis-specific Drosophila cohesion protein. PMID:25194162
Mentoring Program Enhancements Supporting Effective Mentoring of Children of Incarcerated Parents.
Stump, Kathryn N; Kupersmidt, Janis B; Stelter, Rebecca L; Rhodes, Jean E
2018-04-26
Children of incarcerated parents (COIP) are at risk for a range of negative outcomes; however, participating in a mentoring relationship can be a promising intervention for these youth. This study examined the impact of mentoring and mentoring program enhancements on COIP. Secondary data analyses were conducted on an archival database consisting of 70,729 matches from 216 Big Brothers Big Sisters (BBBS) local agencies to establish the differential effects of mentoring on COIP. A subset of 45 BBBS agencies, representing 25,252 matches, participated in a telephone interview about program enhancements for better serving COIP. Results revealed that enhanced program practices, including having specific program goals, providing specialized mentor training, and receiving additional funding resulted in better outcomes for COIP matches. Specifically, specialized mentor training and receiving additional funding for serving matches containing COIP were associated with longer and stronger matches. Having specific goals for serving COIP was associated with higher educational expectations in COIP. Results are discussed in terms of benefits of a relationship-based intervention for addressing the needs of COIP and suggestions for program improvements when mentoring programs are serving this unique population of youth. © Society for Community Research and Action 2018.
Sibling Communication in "Star Trek: The Next Generation": Conflicts between Brothers.
ERIC Educational Resources Information Center
Fuss-Reineck, Marilyn
"Star Trek: The Next Generation" depicts sibling relationships between Data and Lore (android), Worf and Kurn (Klingon) and Jean-Luc and Robert (human) that illustrate conflictual communication and suggest teaching applications. The most disturbing empirical communication research on conflict between brothers reports that male sibling…
47 CFR 97.509 - Administering VE requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 97.509 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO... comply with their instructions. (d) No VE may administer an examination to his or her spouse, children, grandchildren, stepchildren, parents, grandparents, stepparents, brothers, sisters, stepbrothers, stepsisters...
Rodríguez, E M; Parra, M T; Rufas, J S; Suja, J A
2001-12-01
In somatic cells colchicine promotes the arrest of cell division at prometaphase, and chromosomes show a sequential loss of sister chromatid arm and centromere cohesion. In this study we used colchicine to analyse possible changes in chromosome structure and sister chromatid cohesion in prometaphase I-arrested bivalents of the katydid Pycnogaster cucullata. After silver staining we observed that in colchicine-arrested prometaphase I bivalents, and in contrast to what was found in control bivalents, sister kinetochores appeared individualised and sister chromatid axes were completely separated all along their length. However, this change in chromosome structure occurred without loss of sister chromatid arm cohesion. We also employed the MPM-2 monoclonal antibody against mitotic phosphoproteins on control and colchicine-treated spermatocytes. In control metaphase I bivalents this antibody labelled the tightly associated sister kinetochores and the interchromatid domain. By contrast, in colchicine-treated prometaphase I bivalents individualised sister kinetochores appeared labelled, but the interchromatid domain did not show labelling. These results support the notion that MPM-2 phosphoproteins, probably DNA topoisomerase IIalpha, located in the interchromatid domain act as "chromosomal staples" associating sister chromatid axes in metaphase I bivalents. The disappearance of these chromosomal staples would induce a change in chromosome structure, as reflected by the separation of sister kinetochores and sister axes, but without a concomitant loss of sister chromatid cohesion.
NASA Technical Reports Server (NTRS)
Benson, T.; Galica, C.; McCredie, P.; Storm, R.
2003-01-01
This guide was produced by the NASA Glenn Research Center Office of Educational Programs in Cleveland, OH, and the NASA Aerospace Educational Coordinating Committee. It includes activity modules for students, including the history of the Wright Brothers and their family in Dayton, Ohio and flight experimentation in Kitty Hawk, North Carolina. Student activities such as building models of the Wright Brothers glider and writing press releases of the initial flight are included.
Extreme intrafamilial variability of Saudi brothers with primary hyperoxaluria type 1.
Alfadhel, Majid; Alhasan, Khalid A; Alotaibi, Mohammed; Al Fakeeh, Khalid
2012-01-01
Primary hyperoxaluria type 1 (PH1) is characterized by progressive renal insufficiency culminating in end-stage renal disease, and a wide range of clinical features related to systemic oxalosis in different organs. It is caused by autosomal recessive deficiency of alanine:glyoxylate aminotransferase due to a defect in AGXT gene. Two brothers (one 6 months old; the other 2 years old) presented with acute renal failure and urinary tract infection respectively. PH1 was confirmed by high urinary oxalate level, demonstration of oxalate crystals in bone biopsy, and pathogenic homozygous known AGXT gene mutation. Despite the same genetic background, same sex, and shared environment, the outcome of the two siblings differs widely. While one of them died earlier with end-stage renal disease and multiorgan failure caused by systemic oxalosis, the older brother is pyridoxine responsive with normal development and renal function. Clinicians should be aware of extreme intrafamilial variability of PH1 and international registries are needed to characterize the genotype-phenotype correlation in such disorder.
Valeri, A; Briollais, L; Azzouzi, R; Fournier, G; Mangin, P; Berthon, P; Cussenot, O; Demenais, F
2003-03-01
Four segregation analyses concerning prostate cancer (CaP), three conducted in the United States and one in Northern Europe, have shown evidence for a dominant major gene but with different parameter estimates. A recent segregation analysis of Australian pedigrees has found a better fit of a two-locus model than single-locus models. This model included a dominantly inherited increased risk that was greater at younger ages and a recessively inherited or X-linked increased risk that was greater at older ages. Recent linkage analyses have led to the detection of at least 8 CaP predisposing genes, suggesting a complex inheritance and genetic heterogeneity. To assess the nature of familial aggregation of prostate cancer in France, segregation analysis was conducted in 691 families ascertained through 691 CaP patients, recruited from three French hospitals and unselected with respect to age at diagnosis, clinical stage or family history. This mode of family inclusion, without any particular selection of the probands, is unique, as probands from all previous analyses were selected according to various criteria. Segregation analysis was carried out using the logistic hazard regressive model, as incorporated in the REGRESS program, which can accommodate a major gene effect, residual familial dependences of any origin (genetic and/or environmental), and covariates, while including survival analysis concepts. Segregation analysis showed evidence for the segregation of an autosomal dominant gene (allele frequency of 0.03%) with an additional brother-brother dependence. The estimated cumulative risks of prostate cancer by age 85 years, among subjects with the at-risk genotype, were 86% in the fathers' generation and 99% in the probands' generation. This study supports the model of Mendelian transmission of a rare autosomal dominant gene with high penetrance, and demonstrates that additional genetic and/or common sibling environmental factors are involved to account for the
Big Opportunities and Big Concerns of Big Data in Education
ERIC Educational Resources Information Center
Wang, Yinying
2016-01-01
Against the backdrop of the ever-increasing influx of big data, this article examines the opportunities and concerns over big data in education. Specifically, this article first introduces big data, followed by delineating the potential opportunities of using big data in education in two areas: learning analytics and educational policy. Then, the…
Birth order and sibling sex ratio of children and adolescents referred to a gender identity service.
Vanderlaan, Doug P; Blanchard, Ray; Wood, Hayley; Zucker, Kenneth J
2014-01-01
In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect). In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768). Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females.
Pereira, Sara; Katzmarzyk, Peter T; Gomes, Thayse Natacha; Souza, Michele; Chaves, Raquel N; Santos, Fernanda K Dos; Santos, Daniel; Hedeker, Donald; Maia, José A R
2017-06-01
Somatotype is a complex trait influenced by different genetic and environmental factors as well as by other covariates whose effects are still unclear. To (1) estimate siblings' resemblance in their general somatotype; (2) identify sib-pair (brother-brother (BB), sister-sister (SS), brother-sister (BS)) similarities in individual somatotype components; (3) examine the degree to which between and within variances differ among sib-ships; and (4) investigate the effects of physical activity (PA) and family socioeconomic status (SES) on these relationships. The sample comprises 1058 Portuguese siblings (538 females) aged 9-20 years. Somatotype was calculated using the Health-Carter method, while PA and SES information was obtained by questionnaire. Multi-level modelling was done in SuperMix software. Older subjects showed the lowest values for endomorphy and mesomorphy, but the highest values for ectomorphy; and more physically active subjects showed the highest values for mesomorphy. In general, the familiality of somatotype was moderate (ρ = 0.35). Same-sex siblings had the strongest resemblance (endomorphy: ρ SS > ρ BB > ρ BS ; mesomorphy: ρ BB = ρ SS > ρ BS ; ectomorphy: ρ BB > ρ SS > ρ BS ). For the ectomorphy and mesomorphy components, BS pairs showed the highest between sib-ship variance, but the lowest within sib-ship variance; while for endomorphy BS showed the lowest between and within sib-ship variances. These results highlight the significant familial effects on somatotype and the complexity of the role of familial resemblance in explaining variance in somatotypes.
Impact of social support on bereaved siblings' anxiety: a nationwide follow-up.
Eilertsen, Mary-Elizabeth Bradley; Eilegård, Alexandra; Steineck, Gunnar; Nyberg, Tommy; Kreicbergs, Ulrika
2013-01-01
To assess adolescent and young adult siblings' perception of social support prior to and following the loss of their brother or sister to cancer, 2 to 9 years earlier, and their anxiety at follow-up. In 2009, 174 (73%) bereaved siblings (12-25 years) participated in a nationwide, long-term follow-up study in Sweden using an anonymous study-specific questionnaire. The Hospital Anxiety and Depression Scale was used to measure self-assessed anxiety. Siblings had a higher risk of anxiety if they perceived their need for social support was unsatisfied during their brother or sisters' last month before death, relative risk (RR) = 3.6 (95% confidence interval [CI] = 1.8-7.3); time after death, RR = 2.9 (95% CI = 1.5-5.6); and at follow-up, RR = 3.8 (95% CI = 2.0-7.2). Furthermore, a higher risk for anxiety was shown for siblings if they did not perceive that their parents and neighbors cared for them after their brother or sisters' death, RR = 2.7 (95% CI = 1.3-5.5), RR = 5.4 (95% CI = 1.3-21.9), respectively. Bereaved siblings had a greater probability to report self-assessed anxiety if they perceived that their need for social support was not satisfied prior to and following death. Information from both nurses and other health care professionals to families about the impact of social support may contribute to lessen the siblings' risk of anxiety.
Yeast cohesin complex embraces 2 micron plasmid sisters in a tri-linked catenane complex
Ghosh, Santanu K.; Huang, Chu-Chun; Hajra, Sujata; Jayaram, Makkuni
2010-01-01
Sister chromatid cohesion, crucial for faithful segregation of replicated chromosomes in eukaryotes, is mediated by the multi-subunit protein complex cohesin. The Saccharomyces cerevisiae plasmid 2 micron circle mimics chromosomes in assembling cohesin at its partitioning locus. The plasmid is a multi-copy selfish DNA element that resides in the nucleus and propagates itself stably, presumably with assistance from cohesin. In metaphase cell lysates, or fractions enriched for their cohesed state by sedimentation, plasmid molecules are trapped topologically by the protein ring formed by cohesin. They can be released from cohesin’s embrace either by linearizing the DNA or by cleaving a cohesin subunit. Assays using two distinctly tagged cohesin molecules argue against the hand-cuff (an associated pair of monomeric cohesin rings) or the bracelet (a dimeric cohesin ring) model as responsible for establishing plasmid cohesion. Our cumulative results most easily fit a model in which a single monomeric cohesin ring, rather than a series of such rings, conjoins a pair of sister plasmids. These features of plasmid cohesion account for its sister-to-sister mode of segregation by cohesin disassembly during anaphase. The mechanistic similarities of cohesion between mini-chromosome sisters and 2 micron plasmid sisters suggest a potential kinship between the plasmid partitioning locus and centromeres. PMID:19920123
42 CFR 56.304 - Governing board.
Code of Federal Regulations, 2014 CFR
2014-10-01
... individuals being or to be served in terms of demographic factors, such as race, ethnicity, and sex. (2) No... child, parent, brother or sister by blood of marriage of such an employee. The project director may be a...
42 CFR 56.304 - Governing board.
Code of Federal Regulations, 2012 CFR
2012-10-01
... individuals being or to be served in terms of demographic factors, such as race, ethnicity, and sex. (2) No... child, parent, brother or sister by blood of marriage of such an employee. The project director may be a...
42 CFR 56.304 - Governing board.
Code of Federal Regulations, 2013 CFR
2013-10-01
... individuals being or to be served in terms of demographic factors, such as race, ethnicity, and sex. (2) No... child, parent, brother or sister by blood of marriage of such an employee. The project director may be a...
42 CFR 56.304 - Governing board.
Code of Federal Regulations, 2011 CFR
2011-10-01
... individuals being or to be served in terms of demographic factors, such as race, ethnicity, and sex. (2) No... child, parent, brother or sister by blood of marriage of such an employee. The project director may be a...
32 CFR 1642.1 - Purpose; definitions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 18th anniversary of the registrant's date of birth and is now supported in good faith by the registrant. (4) The term brother or sister shall include a person having one or both parents in common with the...
32 CFR 1642.1 - Purpose; definitions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 18th anniversary of the registrant's date of birth and is now supported in good faith by the registrant. (4) The term brother or sister shall include a person having one or both parents in common with the...
Schuntermann, Peter
2007-01-01
Parents raising a child with significant developmental challenges are profoundly aware of the often sustained impact of that child's special needs upon their other children. Supported by recent research on siblings of developmentally challenged children, clinicians are advocating family-based interventions that take into account the needs of siblings. This article reviews the experience of siblings who live with brothers or sisters diagnosed with pervasive developmental disorder or mental retardation. Contributions from research on typical siblings are drawn upon when appropriate. Six domains of the sibling experience are identified. These domains explore relational shifts within sibling relationships and through the expectable differential parental treatment of each child. Shifts considered in this review include the interrelationships with the extended family, peers, and friendships, all of which contribute to shaping the meaning that siblings give to living with developmentally challenged brothers or sisters across time.
El-Tawil, A M; Nightingale, P; Cox, M A
2013-03-01
The credibility of the "Hygiene hypothesis" in patients with inflammatory bowel disease has been assessed. This survey is aimed at finding an answer for the question: "Does living in crowded or overcrowded houses protect against the development of inflammatory bowel disease?" Asian immigrants to the United Kingdom who attended inflammatory bowel diseases' clinics during the period of the study and who fulfilled Leonard-Jones criteria were asked to complete a questionnaire. The participants were asked to respond to questions on age, sex, their birth rank, diagnosis, & number of brothers, sisters, sons and daughters. 60% of the participants had four or more brothers and sisters. Forty per cent of the participants grew in crowded houses (occupied the fourth birth rank). Our presented data do not support any role of the number of house inhabitants in the development of inflammatory bowel disease.
Bozkurt, Ali; Bozkurt, Ozlem Hekim; Sonmez, Ipek
2015-07-01
Western studies have consistently found that androphilic (sexually attracted to men) male-to-female transsexuals have a later birth order and a relative excess of brothers compared with appropriate control participants. However, non-Western studies on birth order and sibling sex ratio in androphilic males (transsexual or non-transsexual) are rare. The objective of the study was to test the hypothesis that androphilic male-to-female transsexuals have a late birth order and a relative excess of brothers in a non-Western culture with a higher fertility rate. The participants were 60 androphilic male-to-female transsexuals and 61 male heterosexual controls. The transsexual participants had significantly more older brothers than the control participants, but the groups did not differ in their numbers of older sisters, younger brothers, or younger sisters. The foregoing pattern is usually referred to as the "fraternal birth order effect." Slater's and Berglin's Indexes both showed that the mean birth order of the control participants was very close to that expected from a random sample drawn from a demographically stable population whereas the mean birth order of the transsexual participants was later. A measure of sibship composition, brothers/all siblings, showed that the transsexual group had a higher proportion of male siblings compared with the control group. In conclusion, the present study found that Turkish androphilic male-to-female transsexuals show the same high fraternal birth order that has been found in comparable androphilic samples in Western Europe, North America, and the South Pacific, which suggests a common underlying biological causal mechanism.
NASA Astrophysics Data System (ADS)
Keith, Manuel; Haase, Karsten M.; Klemd, Reiner; Smith, Daniel J.; Schwarz-Schampera, Ulrich; Bach, Wolfgang
2018-05-01
Most magmatic-hydrothermal Cu deposits are genetically linked to arc magmas. However, most continental or oceanic arc magmas are barren, and hence new methods have to be developed to distinguish between barren and mineralised arc systems. Source composition, melting conditions, the timing of S saturation and an initial chalcophile element-enrichment represent important parameters that control the potential of a subduction setting to host an economically valuable deposit. Brothers volcano in the Kermadec island arc is one of the best-studied examples of arc-related submarine magmatic-hydrothermal activity. This study, for the first time, compares the chemical and mineralogical composition of the Brothers seafloor massive sulphides and the associated dacitic to rhyolitic lavas that host the hydrothermal system. Incompatible trace element ratios, such as La/Sm and Ce/Pb, indicate that the basaltic melts from L'Esperance volcano may represent a parental analogue to the more evolved Brothers lavas. Copper-rich magmatic sulphides (Cu > 2 wt%) identified in fresh volcanic glass and phenocryst phases, such as clinopyroxene, plagioclase and Fe-Ti oxide suggest that the surrounding lavas that host the Brothers hydrothermal system represent a potential Cu source for the sulphide ores at the seafloor. Thermodynamic calculations reveal that the Brothers melts reached volatile saturation during their evolution. Melt inclusion data and the occurrence of sulphides along vesicle margins indicate that an exsolving volatile phase extracted Cu from the silicate melt and probably contributed it to the overlying hydrothermal system. Hence, the formation of the Cu-rich seafloor massive sulphides (up to 35.6 wt%) is probably due to the contribution of Cu from a bimodal source including wall rock leaching and magmatic degassing, in a mineralisation style that is hybrid between Cyprus-type volcanic-hosted massive sulphide and subaerial epithermal-porphyry deposits.
[Jealousy between siblings in early childhood. Nursing assessment based on a case study].
Puig-Plana, María Pilar
2010-01-01
Childhood jealousy, when a little brother or sister is born, has always been a subject treated within the family environment. Parent's attitude in their interaction with their offspring may increase the response of the jealous child. The emotional expressions of the jealous child may lead to behaviour changes, that may occasionally put the physical integrity of the newborn at risk, since it is the most vulnerable in the family group. In view of the above mentioned, a case of a three-year-old child living with his parents and his nine-month-old sister, is presented. The child shows characteristic behaviour changes of jealousy, such as, rebelliousness, aggressiveness and hyperactivity. The brother's psychomotor discomfort leads to a proneness to accidents for the baby girl and the obvious parental concern. For these reasons nursing intervention in the family group was proposed, based on the theoretical Virginia Henderson Needs Model. The actions will come from the older brother and parents. The aim of the nursing intervention is to lead the behaviour changes in order to re-establish a safe and healthy family environment. Copyright 2009 Elsevier España, S.L. All rights reserved.
7 CFR 3555.8 - Conflict of interest.
Code of Federal Regulations, 2014 CFR
2014-01-01
... following: (1) Immediate family members, including parents and children, whether related by blood or marriage; (2) Close relatives, including grandmother, grandfather, aunt, uncle, sister, brother, niece, nephew, granddaughter, grandson, or first cousin, whether related by blood or marriage; (3) Any household...
Code of Federal Regulations, 2010 CFR
2010-01-01
... person whose management functions relate exclusively to the business of retail merchandising or... Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MANAGEMENT OFFICIAL... immediate family. “Immediate family” means spouse, mother, father, child, grandchild, sister, brother, or...
2018-01-01
Sister kinetochores are connected to the same spindle pole during meiosis I and to opposite poles during meiosis II. The molecular mechanisms controlling the distinct behavior of sister kinetochores during the two meiotic divisions are poorly understood. To study kinetochore behavior during meiosis, we have optimized time lapse imaging with Drosophila spermatocytes, enabling kinetochore tracking with high temporal and spatial resolution through both meiotic divisions. The correct bipolar orientation of chromosomes within the spindle proceeds rapidly during both divisions. Stable bi-orientation of the last chromosome is achieved within ten minutes after the onset of kinetochore-microtubule interactions. Our analyses of mnm and tef mutants, where univalents instead of bivalents are present during meiosis I, indicate that the high efficiency of normal bi-orientation depends on pronounced stabilization of kinetochore attachments to spindle microtubules by the mechanical tension generated by spindle forces upon bi-orientation. Except for occasional brief separation episodes, sister kinetochores are so closely associated that they cannot be resolved individually by light microscopy during meiosis I, interkinesis and at the start of meiosis II. Permanent evident separation of sister kinetochores during M II depends on spindle forces resulting from bi-orientation. In mnm and tef mutants, sister kinetochore separation can be observed already during meiosis I in bi-oriented univalents. Interestingly, however, this sister kinetochore separation is delayed until the metaphase to anaphase transition and depends on the Fzy/Cdc20 activator of the anaphase-promoting complex/cyclosome. We propose that univalent bi-orientation in mnm and tef mutants exposes a release of sister kinetochore conjunction that occurs also during normal meiosis I in preparation for bi-orientation of dyads during meiosis II. PMID:29734336
Effect of chloramphenicol on sister chromatid exchange in bovine fibroblasts.
Arruga, M V; Catalan, J; Moreno, C
1992-03-01
The genotoxic potential of different chloramphenicol concentrations (5, 20, 40 and 60 micrograms ml-1) was investigated in bovine fibroblast primary lines by sister chromatid exchange assay. Chloramphenicol acted for long enough to ensure similar effects to persistent storage in the kidney. In this experiment 10 micrograms ml-1 of 5-bromodeoxyuridine was added for 60 hours for all doses of chloramphenicol and to the control. When the tissue culture cells were exposed to increasing doses, increased numbers of sister chromatid exchanges developed. Differences were significantly different to the control.
Cochlear Implants Keep Twin Sisters Learning, Discovering Together
... University. Photo: Johns Hopkins University Keep Twin Sisters Learning, Discovering Together Mia and Isabelle Jeppsen, 10, share ... her mother, gratefully, "There's the obvious benefit of learning to read, write and communicate with facility and ...
Generativity in Elderly Oblate Sisters of Providence
Black, Helen K.; Hannum, Susan M.; Rubinstein, Robert L.; de Medeiros, Kate
2016-01-01
Purpose of the Study: We explored how generativity and well-being merged in a group of childless older women: African and Hispanic Roman Catholic Religious Sisters, linking two minority identity characteristics. Design and Methods: We qualitatively interviewed 8 Oblate Sisters of Providence (OSP), by providing a framework for examining the range of the women’s generativity—cultural spheres in which generativity is rooted and outlets for generativity. Results: Early negative experiences, such as fleeing despotism in Haiti and Cuba and racism within the Catholic Church, occurred alongside positive experiences—families who stressed education, and Caucasian Religious who taught children of color. This became a foundation for the Sister’s generative commitment. Implications: Findings highlight that research gains from a phenomenological understanding of how religious faith promotes generative cognitions and emotions. Findings also reveal that the experiences of a subculture in society—African-American elderly women religious—add to theories and definitions of generativity. PMID:25352535
Extreme intrafamilial variability of Saudi brothers with primary hyperoxaluria type 1
Alfadhel, Majid; Alhasan, Khalid A; Alotaibi, Mohammed; Al Fakeeh, Khalid
2012-01-01
Background Primary hyperoxaluria type 1 (PH1) is characterized by progressive renal insufficiency culminating in end-stage renal disease, and a wide range of clinical features related to systemic oxalosis in different organs. It is caused by autosomal recessive deficiency of alanine:glyoxylate aminotransferase due to a defect in AGXT gene. Case report Two brothers (one 6 months old; the other 2 years old) presented with acute renal failure and urinary tract infection respectively. PH1 was confirmed by high urinary oxalate level, demonstration of oxalate crystals in bone biopsy, and pathogenic homozygous known AGXT gene mutation. Despite the same genetic background, same sex, and shared environment, the outcome of the two siblings differs widely. While one of them died earlier with end-stage renal disease and multiorgan failure caused by systemic oxalosis, the older brother is pyridoxine responsive with normal development and renal function. Conclusion Clinicians should be aware of extreme intrafamilial variability of PH1 and international registries are needed to characterize the genotype-phenotype correlation in such disorder. PMID:22956877
Two brothers with heart defects and limb shortening: case reports and review.
Reardon, W; Hurst, J; Farag, T I; Hall, C; Baraitser, M
1990-01-01
Two male Arab sibs are reported with congenital heart disease and skeletal malformations. Other published case reports sharing some features in common with these brothers are considered. However, clinical and radiological features in these boys are distinct enough to represent a new cardioskeletal syndrome. Images PMID:2074559
Ghulam Ali v. Ghulam Sarwar Naqvi (Mst.) [15 May 1989].
1989-01-01
In Pakistan, the respondent sought to claim under Islamic law her share of property left by her father to her and her 3 brothers. The brothers opposed her suit on the grounds that she had relinquished her claim because they had expended sums of money on her maintenance, her 2 marriages, and a murder case in which she was involved. The court upheld her claim, ruling that relinquishment of the kind argued by the brothers was against public policy and morality as well as Islamic law, which calls for brothers to protect the rights of their sisters. The court concluded its decision by urging that women be better informed of their rights, particularly those women living in rural areas, and that Islamic law, which protects women, be cleansed of alien customs and laws denigrating the status of women.
Circuits of Spectacle: The Miller Brothers' 101 Ranch Real Wild West
ERIC Educational Resources Information Center
Fields, Alison
2012-01-01
The Miller Brothers' 101 Ranch Real Wild West show ran from 1906 to 1931, outlasting the famous Buffalo Bill's Wild West show by more than a decade. From its beginnings in Oklahoma Territory, the Real Wild West show traveled national and international circuits and built a broad roster of performers, including more than 150 American Indians. During…
How-to-Do-It: Demonstrating Sister Chromatid Exchanges.
ERIC Educational Resources Information Center
Dye, Frank J.
1988-01-01
Outlines procedures for demonstrating and preparing a permanent slide of sister chromatid exchanges and recombination events between the two chromatids of a single chromosome. Provides the name of an additional resource for making preparations of exchanges. (RT)
Sisters at Work: Career and Community Changes.
ERIC Educational Resources Information Center
Briody, Elizabeth K.; Sullivan, Teresa A.
1988-01-01
The authors examine occupational differentiation of U.S. Catholic nuns before and since the Second Vatican Council. Data were collected from interviews with 30 sisters representing 11 congregations. The analysis relates the diversification of their careers to changes in ideology and life-style and to the changing demographic and financial status…
Birth Order and Sibling Sex Ratio of Children and Adolescents Referred to a Gender Identity Service
VanderLaan, Doug P.; Blanchard, Ray; Wood, Hayley; Zucker, Kenneth J.
2014-01-01
In adult male samples, homosexuality is associated with a preponderance of older brothers (i.e., the fraternal birth order effect). In several studies comparing gender dysphoric youth, who are likely to be homosexual in adulthood, to clinical or non-clinical control groups, the findings have been consistent with the fraternal birth order effect in males; however, less is known about unique sibship characteristics of gender dysphoric females. The current study investigated birth order and sibling sex ratio in a large sample of children and adolescents referred to the same Gender Identity Service (N = 768). Probands were classified as heterosexual males, homosexual males, or homosexual females based on clinical diagnostic information. Groups differed significantly in age and sibship size, and homosexual females were significantly more likely to be only children. Subsequent analyses controlled for age and for sibship size. Compared to heterosexual males, homosexual males had a significant preponderance of older brothers and homosexual females had a significant preponderance of older sisters. Similarly, the older sibling sex ratio of homosexual males showed a significant excess of brothers whereas that of homosexual females showed a significant excess of sisters. Like previous studies of gender dysphoric youth and adults, these findings were consistent with the fraternal birth order effect. In addition, the greater frequency of only children and elevated numbers of older sisters among the homosexual female group adds to a small literature on sibship characteristics of potential relevance to the development of gender identity and sexual orientation in females. PMID:24651045
The Sisters of Mercy in the Crimean War: Lessons for Catholic health care
Paradis, Mary Raphael; Hart, Edith Mary; O’Brien, Mary Judith
2017-01-01
In 1856, an appeal went out to nurses in both England and Ireland, and especially to religious nurses, to care for the troops fighting in the Crimean War. The Sisters of Mercy, founded in 1831 by Venerable Catherine McAuley, answered that call. This article describes the enormous challenges the Sisters faced in that mission, which was a test of their nursing skills, flexibility, organizational ability, and their spirit of mercy. The challenges they faced professionally and as religious Sisters, the manner in which they faced those challenges, and their spiritual lives as religious women shaped their ability to give comprehensive care. Some applications are made to the challenges which religious communities and organizations working in health care face in our country at this time. Summary: This article describes the challenges faced by a group of Sisters of Mercy from England and Ireland who volunteered to serve as nurses in the Crimean War from 1856 to 1858. Applications are made to challenges which are faced by religious communities and organizations in the current secular healthcare environment. PMID:28392597
The Sisters of Mercy in the Crimean War: Lessons for Catholic health care.
Paradis, Mary Raphael; Hart, Edith Mary; O'Brien, Mary Judith
2017-02-01
In 1856, an appeal went out to nurses in both England and Ireland, and especially to religious nurses, to care for the troops fighting in the Crimean War. The Sisters of Mercy, founded in 1831 by Venerable Catherine McAuley, answered that call. This article describes the enormous challenges the Sisters faced in that mission, which was a test of their nursing skills, flexibility, organizational ability, and their spirit of mercy. The challenges they faced professionally and as religious Sisters, the manner in which they faced those challenges, and their spiritual lives as religious women shaped their ability to give comprehensive care. Some applications are made to the challenges which religious communities and organizations working in health care face in our country at this time. Summary: This article describes the challenges faced by a group of Sisters of Mercy from England and Ireland who volunteered to serve as nurses in the Crimean War from 1856 to 1858. Applications are made to challenges which are faced by religious communities and organizations in the current secular healthcare environment.
Blanchard, Ray; Lippa, Richard A
2007-04-01
This study investigated the relations among sexual orientation, fraternal birth order (number of older brothers), and hand-preference. The participants were 87,798 men and 71,981 women who took part in a Web-based research project sponsored by the British Broadcasting Corporation (BBC). The results yielded some evidence confirming prior findings that non-right-handedness is associated with homosexuality in men and women, that older brothers increase the odds of homosexuality in men, and that the effect of older brothers on sexual orientation is limited to right-handed men. The evidence was weaker than in previous studies, however, probably because the usual relations among the variables of interest were partially obscured by the effects of other factors. Thus, the homosexual men and women had higher rates of non-right-handedness than their heterosexual counterparts, but the strongest handedness finding for both sexes was a marked tendency for participants who described themselves as ambidextrous also to describe themselves as bisexual. The birth order data were strongly affected by a tendency for the male participants to report an excess of older sisters, and the female participants to report an excess of older brothers. Statistical analyses confirmed that this was an artifact of the parental stopping rule, "Continue having children until you have offspring of both sexes." In subsequent analyses, participants were divided into those who did and did not have younger siblings, on the grounds that the data of the former would be less contaminated by the stopping rule. In the former subsample, the right-handed homo/bisexual males showed the typical high ratio of older brothers to older sisters, whereas the non-right-handed homo/bisexual males did not.
Westergaard, T; Olsen, J H; Frisch, M; Kroman, N; Nielsen, J W; Melbye, M
1996-05-29
There are several reports of familial testicular cancer in the literature but few systematic attempts have been made to estimate the risk of testicular cancer in first-degree relatives of patients with this neoplasm, and the risk remains to be fully assessed in population-based studies. By means of data from the Danish Cancer Registry, we identified all testicular cancer patients (index cases) born and diagnosed during 1950-1993 in Denmark. Their fathers were identified from national registries, as were the brothers of a subcohort of these patients. Familial cancer occurrence was determined through linkage with the cancer registry and compared with the cancer incidence in the general male population in Denmark. The ratio of observed to expected cancers generated the measure used for the relative risk. Fathers of 2,113 index cases with testicular cancer experienced an almost 2-fold risk of developing testicular cancer themselves (RR = 1.96; 95% CI: 1.01-3.43). Overall, the fathers had a decreased relative cancer risk (RR = 0.84; 95% CI: 0.74-0.95) with a significantly decreased risk of cancers of the lung and digestive organs. Brothers of a subcohort of 702 index cases showed a markedly increased risk of testicular cancer (RR = 12.3; 95% CI: 3.3-3 1.5). In conclusion, we documented a significantly increased familial risk of testicular cancer which was relatively more pronounced between brothers than between fathers and sons. These findings support the possible involvement of a genetic component in the aetiology of testicular cancer, but also leave room for a hypothesized influence of in-utero exposures, such as specific maternal hormone levels, that might be shared by brothers.
Sister M. Madeleva Wolff, C.S.C.
ERIC Educational Resources Information Center
Petit, M. Loretta
2006-01-01
Sister M. Madeleva Wolff, C.S.C., teacher, essayist, poet, and college administrator, through her creative ability and innovative practices made possible major contributions to Catholic education in her lifetime. Without her strong personality and boundless energy, many of her dreams for an ideal college curriculum would not have come to fruition.…
Brown and polar bear Y chromosomes reveal extensive male-biased gene flow within brother lineages.
Bidon, Tobias; Janke, Axel; Fain, Steven R; Eiken, Hans Geir; Hagen, Snorre B; Saarma, Urmas; Hallström, Björn M; Lecomte, Nicolas; Hailer, Frank
2014-06-01
Brown and polar bears have become prominent examples in phylogeography, but previous phylogeographic studies relied largely on maternally inherited mitochondrial DNA (mtDNA) or were geographically restricted. The male-specific Y chromosome, a natural counterpart to mtDNA, has remained underexplored. Although this paternally inherited chromosome is indispensable for comprehensive analyses of phylogeographic patterns, technical difficulties and low variability have hampered its application in most mammals. We developed 13 novel Y-chromosomal sequence and microsatellite markers from the polar bear genome and screened these in a broad geographic sample of 130 brown and polar bears. We also analyzed a 390-kb-long Y-chromosomal scaffold using sequencing data from published male ursine genomes. Y chromosome evidence support the emerging understanding that brown and polar bears started to diverge no later than the Middle Pleistocene. Contrary to mtDNA patterns, we found 1) brown and polar bears to be reciprocally monophyletic sister (or rather brother) lineages, without signals of introgression, 2) male-biased gene flow across continents and on phylogeographic time scales, and 3) male dispersal that links the Alaskan ABC islands population to mainland brown bears. Due to female philopatry, mtDNA provides a highly structured estimate of population differentiation, while male-biased gene flow is a homogenizing force for nuclear genetic variation. Our findings highlight the importance of analyzing both maternally and paternally inherited loci for a comprehensive view of phylogeographic history, and that mtDNA-based phylogeographic studies of many mammals should be reevaluated. Recent advances in sequencing technology render the analysis of Y-chromosomal variation feasible, even in nonmodel organisms. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e
Peces, Ramón; Afonso, Sara; Peces, Carlos; Nevado, Julián; Selgas, Rafael
2017-08-31
Familial Mediterranean fever is an autosomal recessive disease characterized by recurrent episodes of fever and polyserositis and by the onset of reactive amyloid-associated amyloidosis. Amyloidosis due to familial Mediterranean fever can lead to end-stage renal disease, culminating in kidney transplantation for some patients. In this study, we report the clinical outcome of two brothers with familial Mediterranean fever who were the inadvertent donor and recipient, respectively, of a kidney. Subsequently, they were diagnosed with renal amyloidosis secondary to familial Mediterranean fever and were successfully treated with anakinra and colchicine. Two brothers with familial Mediterranean fever and renal amyloidosis were the inadvertent donor and recipient, respectively, of a kidney. The recipient had presented recurrent acute febrile episodes of familial Mediterranean fever, developed nephrotic syndrome secondary to amyloidosis and needed bilateral nephrectomy and chronic dialysis. His elder brother, in apparent good health, donated his left kidney to his brother. Immediately after the kidney transplantation, both the donor and recipient presented massive proteinuria, impaired renal function and elevated serum amyloid A levels. Biopsies of the brothers' kidneys showed amyloidosis. Genetic studies thereafter revealed a homozygous variant for the MEFV gene (NM_000243.2.c.2082G > A; p.M694I) in both brothers. At this point, both the donor and recipient were treated with colchicine and anakinra, resulting in improved renal function, decreased proteinuria, undetectable serum amyloid A levels and stable renal function at 62 months of follow-up and no major adverse effects. In familial Mediterranean fever, analyses of the MEFV gene should be performed in potential live kidney donors from a direct family member (either between siblings or between parents and children). In addition, genetic studies are required when consanguinity is suspected between members involved in
Perrault's syndrome in two sisters.
Bösze, P; Skripeczky, K; Gaál, M; Tóth, A; László, J
1983-10-01
We report on two sisters with Perrault's syndrome, i.e., autosomal recessive ovarian dysgenesis associated with sensorineural deafness. They were deaf-mute and of normal height with a few minor somatic anomalies. Both had streak gonads and an apparently normal female 46,XX chromosome constitution. The parents were apparently not consanguineous. The mother had normal hearing. Other relatives were not available for study. Epilepsy, which occurred in three relatives including one of the index patients, may have been inherited coincidentally from the mother's family.
Sibling Incest: A Hong Kong Experience.
ERIC Educational Resources Information Center
Tsun, O. K. Angela
1999-01-01
Presents a case study of a Hong Kong Chinese adult survivor of brother-sister incest. Discusses her symptoms, feelings toward incest, parental response at disclosures, and implications for practice. Also discusses Chinese cultural influences that affect the family and lead to secrecy and shame. (CR)
Learning Emotional Understanding and Emotion Regulation through Sibling Interaction
ERIC Educational Resources Information Center
Kramer, Laurie
2014-01-01
Research Findings: Young children's relationships with their sisters and brothers offer unique and important opportunities for learning about emotions and developing emotional understanding. Through a critical analysis, this article examines sibling interaction in 3 different but normative contexts (conflict/conflict management, play, and…
20 CFR 222.44 - Other relationship determinations for lump-sum payments.
Code of Federal Regulations, 2010 CFR
2010-04-01
... THE RAILROAD RETIREMENT ACT FAMILY RELATIONSHIPS Relationship as Parent, Grandchild, Brother or Sister § 222.44 Other relationship determinations for lump-sum payments. Other claimants will be considered to... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Other relationship determinations for lump...
Code of Federal Regulations, 2011 CFR
2011-01-01
... election, by the Board of Governors of the Federal Reserve System. (l) Immediate family member of a natural person means the spouse, father, mother, brother, sister, son or daughter of that natural person. (m..., association, foundation, joint venture, pool, syndicate, sole proprietorship, unincorporated organization, or...
Code of Federal Regulations, 2010 CFR
2010-01-01
... election, by the Board of Governors of the Federal Reserve System. (l) Immediate family member of a natural person means the spouse, father, mother, brother, sister, son or daughter of that natural person. (m..., association, foundation, joint venture, pool, syndicate, sole proprietorship, unincorporated organization, or...
Ectodermal dysplasia with blindness in sibs on the island of Rodrigues.
Wallis, C E; Beighton, P
1992-01-01
A brother and sister from the island of Rodrigues had mental retardation, blindness owing to severe ocular malformations, short stature, dysmorphic facial features, hypotrichosis, and dental abnormalities. It is likely that they have a hitherto unrecognised autosomal recessive ectodermal dysplasia syndrome. Images PMID:1583659
20 CFR 416.1231 - Burial spaces and certain funds set aside for burial expenses.
Code of Federal Regulations, 2010 CFR
2010-04-01
... children and step-children; an individual's brothers, sisters, parents, adoptive parents, and the spouses... are set aside for the burial arrangements of the eligible child's ineligible parent or parent's spouse... separation; i.e., a circumstance beyond an individual's control which makes conversion/separation impossible...
Siblings of the Handicapped: Maladjustment and Its Prevention.
ERIC Educational Resources Information Center
Hannah, Mary Elizabeth; Midlarsky, Elizabeth
1987-01-01
The mental health consequences of having a handicapped brother or sister and factors that may be related to psychological adjustment are discussed. Also explored are the use of parental consultation, behavior modification, and discussion groups as potential intervention strategies with siblings of the handicapped. (Author)
28 CFR 570.42 - Non-medical escorted trips.
Code of Federal Regulations, 2010 CFR
2010-07-01
... member of an inmate's immediate family. For purposes of this rule, immediate family refers to mother, father, brother, sister, spouse, children, step-parents, and foster parents. (2) Non-emergency, non... persons (e.g., attending physician, hospital staff, funeral home staff, family members, U.S. Probation...
Dhawale, Ashesh K.; Hagiwara, Akari; Bhalla, Upinder S.; Murthy, Venkatesh N.; Albeanu, Dinu F.
2011-01-01
Sensory inputs frequently converge on the brain in a spatially organized manner, often with overlapping inputs to multiple target neurons. Whether the responses of target neurons with common inputs become decorrelated depends on the contribution of local circuit interactions. We addressed this issue in the olfactory system using newly generated transgenic mice expressing channelrhodopsin-2 in all olfactory sensory neurons. By selectively stimulating individual glomeruli with light, we identified mitral/tufted (M/T) cells that receive common input (sister cells). Sister M/T cells had highly correlated responses to odors as measured by average spike rates, but their spike timing in relation to respiration was differentially altered. In contrast, non-sister M/T cells correlated poorly on both these measures. We suggest that sister M/T cells carry two different channels of information: average activity representing shared glomerular input, and phase-specific information that refines odor representations and is substantially independent for sister M/T cells. PMID:20953197
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
Kajtez, Janko; Solomatina, Anastasia; Novak, Maja; Polak, Bruno; Vukušić, Kruno; Rüdiger, Jonas; Cojoc, Gheorghe; Milas, Ana; Šumanovac Šestak, Ivana; Risteski, Patrik; Tavano, Federica; Klemm, Anna H.; Roscioli, Emanuele; Welburn, Julie; Cimini, Daniela; Glunčić, Matko; Pavin, Nenad; Tolić, Iva M.
2016-01-01
During metaphase, forces on kinetochores are exerted by k-fibres, bundles of microtubules that end at the kinetochore. Interestingly, non-kinetochore microtubules have been observed between sister kinetochores, but their function is unknown. Here we show by laser-cutting of a k-fibre in HeLa and PtK1 cells that a bundle of non-kinetochore microtubules, which we term ‘bridging fibre', bridges sister k-fibres and balances the interkinetochore tension. We found PRC1 and EB3 in the bridging fibre, suggesting that it consists of antiparallel dynamic microtubules. By using a theoretical model that includes a bridging fibre, we show that the forces at the pole and at the kinetochore depend on the bridging fibre thickness. Moreover, our theory and experiments show larger relaxation of the interkinetochore distance for cuts closer to kinetochores. We conclude that the bridging fibre, by linking sister k-fibres, withstands the tension between sister kinetochores and enables the spindle to obtain a curved shape. PMID:26728792
Coloured sweat in two brothers: First report of familial chromhidrosis.
Gaffney, Daniel C; Cooper, Hywel L
2016-02-01
The uncommon diagnosis of chromhidrosis is most frequently made in young adults. This sweat gland disease, although benign, may impact significantly on the patient's quality of life. We describe the first report of familial chromhidrosis of pseudo-eccrine type (pseudochromhidrosis) occurring in two brothers aged 9 and 12 years. The classification and causality of chromhidrosis is described and approaches to assessment and management are outlined. © 2015 The Australasian College of Dermatologists.
Sister chromatid exchanges induced by inhaled anesthetics
DOE Office of Scientific and Technical Information (OSTI.GOV)
White,A.E.; Takehisa, S.; Eger II, E.I.
1970-05-01
There is sufficient evidence that anesthetics may cause cancer to justify a test of their carcinogenic potential. Baden et al., using the Ames test, a rapid and inexpensive genetic indicator of carcinogenicity, have shown that among currently used anesthetics fluorxene alone caused bacterial mutations. The authors used the sister chromatid exchange (SCE) technique, another rapid assay of mutagenic-carcinogenic potential. The frequency of sister chromatid exchanges in Chinese hamster ovary cells increases when the cell cultures are exposed to mutagen-carcinogens, particulary in the presence of a metabolic activating system. With this test system a one-hour exposure to 1 MAC nitrous oxide,more » diethyl ether, trichloroethylene, halothane, enflurane, isoflurane, methoxyflurane, or chloroform did not increase SCE values. Divinyl ether, fluroxene and ethyl vinyl ether increased SCE values in the same circumstances. Results of this study of mammalian cells suggest that no currently used anesthetic is a mutagen-carcinogen. The results also suggest that anesthetics containing a vinyl moiety may be mutagen-carcinogens.« less
East, Patricia L; Khoo, Siek Toon
2005-12-01
This 3-wave, 5-year longitudinal study tested the contributions of family contextual factors and sibling relationship qualities to younger siblings' substance use, sexual risk behaviors, pregnancy, and sexually transmitted disease. More than 220 non-White families participated (67% Latino and 33% African American), all of which involved a younger sibling (133 girls and 89 boys; mean age = 13.6 years at Time 1) and an older sister (mean age = 17 years at Time 1). Results from structural equation latent growth curve modeling indicated that qualities of the sibling relationship (high older sister power, low warmth/closeness, and low conflict) mediated effects from several family risks (mothers' single parenting, older sisters' teen parenting, and family's receipt of aid) to younger sibling outcomes. Model results were generally stronger for sister-sister pairs than for sister-brother pairs. Findings add to theoretical models that emphasize the role of family and parenting processes in shaping sibling relationships, which, in turn, influence adolescent outcomes. Copyright 2006 APA, all rights reserved).
Djernæs, Marie; Klass, Klaus-Dieter; Eggleton, Paul
2015-03-01
Termites (Isoptera) offer an alternative model for the development of eusociality which is not dependent on a high degree of relatedness as found between sisters in hymenopterans (bees, wasps, ants). Recent phylogenetic studies have established that termites belong within the cockroaches as sister to the subsocial Cryptocercidae. Cryptocercidae shares several important traits with termites, thus we need to understand the phylogenetic position of Cryptocercidae+Isoptera to determine how these traits evolved. However, placement of Cryptocercidae+Isoptera is still uncertain. We used both molecular (12S, 16S, COII, 18S, 28S, H3) and morphological characters to reconstruct the phylogeny of Dictyoptera. We included all previously suggested sister groups of Cryptocercidae+Isoptera as well as taxa which might represent additional major cockroach lineages. We used Bayes factors to test different sister groups for Cryptocercidae+Isoptera and assessed character support for the consensus tree based on morphological characters and COII amino acid data. We used the molecular data and fossil calibration to estimate divergence times. We found the most likely sister groups of Cryptocercidae+Isoptera to be Tryonicidae, Anaplecta or Tryonicidae+Anaplecta. Anaplecta has never previously been suggested as sister group or even close to Cryptocercidae+Isoptera, but was formerly placed in Blaberoidea as sister to the remaining taxa. Topological tests firmly supported our new placement of Anaplecta. We discuss the morphological characters (e.g. retractable genitalic hook) that have contributed to the previous placement of Anaplecta in Blaberoidea as well as the factors that might have contributed to a parallel development of genitalic features in Anaplecta and Blaberoidea. Cryptocercidae+Isoptera is placed in a clade with Tryonicidae, Anaplecta and possibly Lamproblattidae. Based on this, we suggest that wood-feeding, and the resultant need to conserve nitrogen, may have been an important
Yin, Shen; Ai, Jun-Shu; Shi, Li-Hong; Wei, Liang; Yuan, Ju; Ouyang, Ying-Chun; Hou, Yi; Chen, Da-Yuan; Schatten, Heide; Sun, Qing-Yuan
2008-01-01
Background Homologous chromosomes separate in meiosis I and sister chromatids separate in meiosis II, generating haploid gametes. To address the question why sister chromatids do not separate in meiosis I, we explored the roles of Shogoshin1 (Sgo1) in chromosome separation during oocyte meiosis. Methodology/Principal Findings Sgo1 function was evaluated by exogenous overexpression to enhance its roles and RNAi to suppress its roles during two meioses of mouse oocytes. Immunocytochemistry and chromosome spread were used to evaluate phenotypes. The exogenous Sgo1 overexpression kept homologous chromosomes and sister chromatids not to separate in meiosis I and meiosis II, respectively, while the Sgo1 RNAi promoted premature separation of sister chromatids. Conclusions Our results reveal that prevention of premature separation of sister chromatids in meiosis I requires the retention of centromeric Sgo1, while normal separation of sister chromatids in meiosis II requires loss of centromeric Sgo1. PMID:18949044
How Big Are "Martin's Big Words"? Thinking Big about the Future.
ERIC Educational Resources Information Center
Gardner, Traci
"Martin's Big Words: The Life of Dr. Martin Luther King, Jr." tells of King's childhood determination to use "big words" through biographical information and quotations. In this lesson, students in grades 3 to 5 explore information on Dr. King to think about his "big" words, then they write about their own…
Mentoring Relationships and the Mental Health of Aboriginal Youth in Canada.
DeWit, David J; Wells, Samantha; Elton-Marshall, Tara; George, Julie
2017-04-01
We compared the mentoring experiences and mental health and behavioral outcomes associated with program-supported mentoring for 125 Aboriginal (AB) and 734 non-Aboriginal (non-AB) youth ages 6-17 participating in a national survey of Big Brothers Big Sisters community mentoring relationships. Parents or guardians reported on youth mental health and other outcomes at baseline (before youth were paired to a mentor) and at 18 months follow-up. We found that AB youth were significantly less likely than non-AB youth to be in a long-term continuous mentoring relationship. However, AB youth were more likely than non-AB youth to be in a long-term relationship ending in dissolution. AB youth were also more likely than non-AB youth to have been mentored by a female adult. AB youth were significantly more likely than non-AB youth to report a high quality mentoring relationship, regular weekly contact with their mentor, and monthly mentoring activities. Structural equation model results revealed that, relative to non-mentored AB youth, AB youth with mentors experienced significantly fewer emotional problems and symptoms of social anxiety. These relationships were not found for non-AB youth. Our findings suggest that mentoring programs may be an effective intervention for improving the health and well-being of AB youth.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-24
... DEPARTMENT OF STATE [Public Notice 7855] Culturally Significant Objects Imported for Exhibition; Determinations: ``Quay Brothers: On Deciphering the Pharmacist's Prescription for Lip-Reading Puppets'' AGENCY...: On Deciphering the Pharmacist's Prescription for Lip-Reading Puppets'' imported from abroad for...
ERIC Educational Resources Information Center
Burke, Meghan M.; Taylor, Julie Lounds; Urbano, Richard; Hodapp, Robert M.
2012-01-01
With the growing life expectancy for individuals with intellectual and developmental disabilities, siblings will increasingly assume responsibility for the care of their brother or sister with intellectual and developmental disabilities. Using a 163-item survey completed by 757 siblings, the authors identified factors related to future caregiving…
ERIC Educational Resources Information Center
Bank, Stephen P.; Kahn, Michael D.
The relationships among brothers and sisters are infinitely varied, but whatever their characteristics, these bonds last throughout life. This book examines the sibling relationship as a distinctive emotional, passionate, painful, and solacing power. Chapter 1, "Unraveling the Sibling Bond," addresses research on siblings and development of the…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-03
... partners of Federal employees, and, where applicable, to the children of same- sex domestic partners of... include ``Domestic partner'' and children, dependent parents, and dependent brothers and sisters of the... respective departments and agencies to determine what authority they have to extend such benefits to same-sex...
76 FR 20215 - National Volunteer Week, 2011
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-12
... America A Proclamation America's story has been marked by the service of volunteers. Generations of... youth and caring for older Americans to supporting our veterans and military families and rebuilding... that we are our brother's keeper and our sister's keeper. Today, as many Americans face hardship, we...
78 FR 22526 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-16
...); (4) United States Social Security Number (SSN), (if any), United States Immigration and Naturalization Service (INS) Identification or similar number(s), (if any), and any equivalent social security or...) spouse; (c) children; (d) brothers; (e) sisters; (f) others; (9) team name; (10) place of insertion; (11...
The younger siblings of teenage mothers: a follow-up of their pregnancy risk.
East, P L; Jacobson, L J
2001-03-01
This study followed 243 younger brothers and younger sisters of parenting teens and nonparenting teens across a 1.5-year period. The average age of siblings was 13.6 years at Time 1 and 15 years at Time 2. Relative to other youths, the sisters of parenting teens exhibited a sharp increase in drug and alcohol use and partying behavior across time and had the highest pregnancy rate at Time 2 (15%). The siblings of parenting teens spent 10 hr a week caring for their sisters' children, and, for girls, many hours of child care was associated with negative outcomes including permissive sexual behavior. Findings suggest that the younger sisters of parenting teens are at very high risk of early pregnancy and that this risk becomes increasingly pronounced across time.
Kin recognition and adjustment of reproductive effort in zebra finches.
Arct, Aneta; Rutkowska, Joanna; Martyka, Rafal; Drobniak, Szymon M; Cichon, Mariusz
2010-12-23
The differential allocation theory predicts that females should invest more in offspring produced with attractive partners, and a number of studies support this prediction in birds. Females have been shown to increase reproductive investment when mated to males showing elaborated sexual traits. However, mate attractiveness might also depend on the interaction between male and female genotypes. Accordingly, females should invest more in offspring sired by individuals that are genetically dissimilar or carry superior alleles. Here, we show in zebra finches (Taeniopygia guttata) that pairs of unfamiliar genetic brothers and sisters are less likely to reproduce in comparison with randomly mated pairs. Among the brother-sister pairs, those that attempted to breed laid smaller clutches and of lower total clutch mass. Our results provide the first experimental evidence that females adjust their reproductive effort in response to the genetic similarity of their partners. Importantly, these results imply a female ability to assess relatedness of a social mate without prior association.
Intralocus sexual conflict over human height
Stulp, Gert; Kuijper, Bram; Buunk, Abraham P.; Pollet, Thomas V.; Verhulst, Simon
2012-01-01
Intralocus sexual conflict (IASC) occurs when a trait under selection in one sex constrains the other sex from achieving its sex-specific fitness optimum. Selection pressures on body size often differ between the sexes across many species, including humans: among men individuals of average height enjoy the highest reproductive success, while shorter women have the highest reproductive success. Given its high heritability, IASC over human height is likely. Using data from sibling pairs from the Wisconsin Longitudinal Study, we present evidence for IASC over height: in shorter sibling pairs (relatively) more reproductive success (number of children) was obtained through the sister than through the brother of the sibling pair. By contrast, in average height sibling pairs most reproductive success was obtained through the brother relative to the sister. In conclusion, we show that IASC over a heritable, sexually dimorphic physical trait (human height) affects Darwinian fitness in a contemporary human population. PMID:22875819
Comparison of assessment of personality disorder by patients and informants.
Modestin, J; Puhan, A
2000-01-01
The present study evaluated the pathology of personality disorder in a group of 8 nonpatient volunteers and 32 psychiatric in- and outpatients, most of them suffering from substance abuse disorder. The patient self-reports were compared with the reports by 2 informants for each proband. All probands and informants completed the Structured Interview for DSM-III-R Axis II Personality Questionnaire. Patient self-reports and informant reports yielded the same number of diagnoses. The diagnostic agreement between the three sets of data was generally poor; however, the concordance was slightly better between both groups of informants than between patients and informants: Median kappa were 0.13 for patients versus parents, 0.14 for patients versus brothers/sisters and 0.29 for parents versus brothers/sisters. Patient and informant evaluations represent two different assessment approaches of the personality, and a complete agreement is not to be expected. Copyright 2000 S. Karger AG, Basel.
ERIC Educational Resources Information Center
Graves, Scott L., Jr.; Aston, Candice
2018-01-01
The purpose of this study is to evaluate the effects of a social emotional learning curriculum, "Brothers of Ujima," for children at risk for being referred for placement in emotional and behavioral support classrooms. The "Brothers of Ujima" is a strength-based culturally relevant intervention for African American boys aged…
Marriage Institutions and Sibling Competition: Evidence from South Asia*
Vogl, Tom S
2013-08-01
Using data from South Asia, this article examines how arranged marriage cultivates rivalry among sisters. During marriage search, parents with multiple daughters reduce the reservation quality for an older daughter's groom, rushing her marriage to allow sufficient time to marry off her younger sisters. Relative to younger brothers, younger sisters increase a girl's marriage risk; relative to younger singleton sisters, younger twin sisters have the same effect. These effects intensify in marriage markets with lower sex ratios or greater parental involvement in marriage arrangements. In contrast, older sisters delay a girl's marriage. Because girls leave school when they marry and face limited earning opportunities when they reach adulthood, the number of sisters has well-being consequences over the life cycle. Younger sisters cause earlier school-leaving, lower literacy, a match to a husband with less education and a less skilled occupation, and (marginally) lower adult economic status. Data from a broader set of countries indicate that these cross-sister pressures on marriage age are common throughout the developing world, although the schooling costs vary by setting. JEL Codes: J1, I25, O15.
Marriage Institutions and Sibling Competition: Evidence from South Asia*
Vogl, Tom S.
2013-01-01
Using data from South Asia, this article examines how arranged marriage cultivates rivalry among sisters. During marriage search, parents with multiple daughters reduce the reservation quality for an older daughter’s groom, rushing her marriage to allow sufficient time to marry off her younger sisters. Relative to younger brothers, younger sisters increase a girl’s marriage risk; relative to younger singleton sisters, younger twin sisters have the same effect. These effects intensify in marriage markets with lower sex ratios or greater parental involvement in marriage arrangements. In contrast, older sisters delay a girl’s marriage. Because girls leave school when they marry and face limited earning opportunities when they reach adulthood, the number of sisters has well-being consequences over the life cycle. Younger sisters cause earlier school-leaving, lower literacy, a match to a husband with less education and a less skilled occupation, and (marginally) lower adult economic status. Data from a broader set of countries indicate that these cross-sister pressures on marriage age are common throughout the developing world, although the schooling costs vary by setting. JEL Codes: J1, I25, O15. PMID:23966752
Blood Brothers: Albert and Allen Hughes in the Belly of the Hollywood Beast.
ERIC Educational Resources Information Center
Gates, Henry Louis, Jr.
1994-01-01
Recounts an interview with the Hughes brothers, who are twin black men who produced the film "Menace 2 Society," which is a film about urban delinquency and crime among black adolescents. Their comments include thoughts on racism, media stereotyping, being black in America, and their experiences with Hollywood. (GLR)
EarthLabs Meet Sister Corita Kent
NASA Astrophysics Data System (ADS)
Quartini, E.; Ellins, K. K.; Cavitte, M. G.; Thirumalai, K.; Ledley, T. S.; Haddad, N.; Lynds, S. E.
2013-12-01
The EarthLabs project provides a framework to enhance high school students' climate literacy and awareness of climate change. The project provides climate science curriculum and teacher professional development, followed by research on students' learning as teachers implement EarthLabs climate modules in the classroom. The professional development targets high school teachers whose professional growth is structured around exposure to current climate science research, data observation collection and analysis. During summer workshops in Texas and Mississippi, teachers work through the laboratories, experiments, and hand-on activities developed for their students. In summer 2013, three graduate students from the University of Texas at Austin Institute for Geophysics with expertise in climate science participated in two weeklong workshops. The graduate students partnered with exemplary teacher leaders to provide scientific content and lead the EarthLabs learning activities. As an experiment, we integrated a visit to the Blanton Museum and an associated activity in order to motivate participants to think creatively, as well as analytically, about science. This exercise was inspired by the work and educational philosophy of Sister Corita Kent. During the visit to the Blanton Museum, we steered participants towards specific works of art pre-selected to emphasize aspects of the climate of Texas and to draw participants' attention to ways in which artists convey different concepts. For example, artists use of color, lines, and symbols conjure emotional responses to imagery in the viewer. The second part of the exercise asked participants to choose a climate message and to convey this through a collage. We encouraged participants to combine their experience at the museum with examples of Sister Corita Kent's artwork. We gave them simple guidelines for the project based on techniques and teaching of Sister Corita Kent. Evaluation results reveal that participants enjoyed the
Big Data, Big Problems: A Healthcare Perspective.
Househ, Mowafa S; Aldosari, Bakheet; Alanazi, Abdullah; Kushniruk, Andre W; Borycki, Elizabeth M
2017-01-01
Much has been written on the benefits of big data for healthcare such as improving patient outcomes, public health surveillance, and healthcare policy decisions. Over the past five years, Big Data, and the data sciences field in general, has been hyped as the "Holy Grail" for the healthcare industry promising a more efficient healthcare system with the promise of improved healthcare outcomes. However, more recently, healthcare researchers are exposing the potential and harmful effects Big Data can have on patient care associating it with increased medical costs, patient mortality, and misguided decision making by clinicians and healthcare policy makers. In this paper, we review the current Big Data trends with a specific focus on the inadvertent negative impacts that Big Data could have on healthcare, in general, and specifically, as it relates to patient and clinical care. Our study results show that although Big Data is built up to be as a the "Holy Grail" for healthcare, small data techniques using traditional statistical methods are, in many cases, more accurate and can lead to more improved healthcare outcomes than Big Data methods. In sum, Big Data for healthcare may cause more problems for the healthcare industry than solutions, and in short, when it comes to the use of data in healthcare, "size isn't everything."
Broad phylogenomic sampling and the sister lineage of land plants.
Timme, Ruth E; Bachvaroff, Tsvetan R; Delwiche, Charles F
2012-01-01
The tremendous diversity of land plants all descended from a single charophyte green alga that colonized the land somewhere between 430 and 470 million years ago. Six orders of charophyte green algae, in addition to embryophytes, comprise the Streptophyta s.l. Previous studies have focused on reconstructing the phylogeny of organisms tied to this key colonization event, but wildly conflicting results have sparked a contentious debate over which lineage gave rise to land plants. The dominant view has been that 'stoneworts,' or Charales, are the sister lineage, but an alternative hypothesis supports the Zygnematales (often referred to as "pond scum") as the sister lineage. In this paper, we provide a well-supported, 160-nuclear-gene phylogenomic analysis supporting the Zygnematales as the closest living relative to land plants. Our study makes two key contributions to the field: 1) the use of an unbiased method to collect a large set of orthologs from deeply diverging species and 2) the use of these data in determining the sister lineage to land plants. We anticipate this updated phylogeny not only will hugely impact lesson plans in introductory biology courses, but also will provide a solid phylogenetic tree for future green-lineage research, whether it be related to plants or green algae.
Sibling Socialization: The Effects of Stressful Life Events and Experiences
ERIC Educational Resources Information Center
Conger, Katherine J.; Stocker, Clare; McGuire, Shirley
2009-01-01
Stressful life events and experiences may disrupt the typical day-to-day interactions between sisters and brothers that provide the foundation of sibling socialization. This chapter examines four experiences that may affect patterns of sibling interaction: parental marital conflict, parental divorce and remarriage, foster care placement, and a…
29 CFR 15.21 - Filing of claims.
Code of Federal Regulations, 2011 CFR
2011-07-01
... filed by a survivor in the following order of preference: spouse, children, parent, brother or sister or... responsible for substantiating ownership or possession, the facts surrounding the loss or damage, and the... which the damage or loss occurred. This statement shall also include: (i) A description of the type...
29 CFR 15.21 - Filing of claims.
Code of Federal Regulations, 2010 CFR
2010-07-01
... filed by a survivor in the following order of preference: spouse, children, parent, brother or sister or... responsible for substantiating ownership or possession, the facts surrounding the loss or damage, and the... which the damage or loss occurred. This statement shall also include: (i) A description of the type...
Benefits of Including Siblings in the Treatment of Autism Spectrum Disorders
ERIC Educational Resources Information Center
Ferraioli, Suzannah J.; Hansford, Amy; Harris, Sandra L.
2012-01-01
Having a brother or sister with an autism spectrum disorder (ASD) can significantly impact the life of a typically developing sibling. These relationships are generally characterized by less frequent and nurturing interactions than are evident in sibling constellations with neurotypical children or children with other developmental disabilities.…
Preventive Therapy with Siblings of a Dying Child.
ERIC Educational Resources Information Center
Feinberg, Daniel
A case study of psychiatric intervention for two sisters whose brother is dying of leukemia is presented. The therapeutic technique attempted to deal with the threatened loss by a forthright approach to the reality situation, encouraging "immunizing" discussions, allowance for catharsis without severe regression, emphasis on reality orientation,…
Attentional Control and Asymmetric Associative Priming
ERIC Educational Resources Information Center
Hutchison, Keith A.; Heap, Shelly J.; Neely, James H.; Thomas, Matthew A.
2014-01-01
Participants completed a battery of 3 attentional control (AC) tasks (OSPAN, antisaccade, and Stroop, as in Hutchison, 2007) and performed a lexical decision task with symmetrically associated (e.g., "sister-brother") and asymmetrically related primes and targets presented in both the forward (e.g., "atom-bomb") and backward…
Support for Teens When a Family Member has Cancer
When a parent, brother, or sister has been diagnosed with cancer, family members need extra support. Information to help teens learn how to cope, talk with family members, manage stress, and get support from counselors when a loved one has been diagnosed with, or is being treated for, cancer.
Disrupted lives: siblings of disturbed adolescents.
Deal, S N; MacLean, W E
1995-04-01
The impact of disturbed adolescents on siblings' psychological adjustment and sibling relationships was examined. Compared to siblings of nondisturbed adolescents, siblings of previously hospitalized adolescents reported more psychological distress, poorer social relationships, a more negative view of their older brothers and sisters, and less identification with their older siblings.
... will help a kid stay healthy and feel good. What Is Insulin? The most common diabetes medicine is insulin, which you can get through shots or an insulin pump . Insulin is a hormone that helps ... also might be a good idea for older brothers and sisters, babysitters, teachers, ...
The Forgotten Children--Siblings of the Handicapped: A Family Systems Perspective.
ERIC Educational Resources Information Center
Hanold, Eleanor Johnson
This study examined dynamics of families with handicapped children by focusing on the emotional, intellectual, and behavioral manner in which the undiagnosed siblings experience the diagnosis and existence of a brother's or sister's handicap within the context of their families. Subjects were 8 socioeconomically middle class families consisting of…
Relationship of Order and Number of Siblings to Perceived Parental Attitudes in Childhood.
ERIC Educational Resources Information Center
Kitamura, Toshinori; Sugawara, Masumi; Shima, Satoru; Toda, Mari A.
1998-01-01
Explores the relationship between numbers and sexes of siblings and perceived rearing practices. Uses the Parental Bonding Instrument to rate responses of 1,145 pregnant Japanese women. Determines participants with more older sisters felt their parents were less caring; participants with more brothers, specifically younger, saw their parents as…
Gliding Experiments of the Wright Brothers: The Wrights and Flight Research 1899-1908
NASA Technical Reports Server (NTRS)
Bowers, Al; Cole, Jennifer Hansen; Martin, Cam
2007-01-01
This viewgraph presentation reviews the experiments that the Wright Brothers conducted prior to their first powered flight in 1903 to developing the first practical aircraft in 1905. Many pictures of the gliders and other devices are used to illustrate the gradual development and experimentation that preceeded the first powered flight.
Laporte, Lise; Paris, Joel; Guttman, Herta; Russell, Jennifer
2011-08-01
The aim of this study was to document and compare adverse childhood experiences, and personality profiles in women with borderline personality disorder (BPD) and their sisters, and to determine how these factors impact current psychopathology. Fifty-six patients with BPD and their sisters were compared on measures assessing psychopathology, personality traits, and childhood adversities. Most sisters showed little evidence of psychopathology. Both groups reported dysfunctional parent-child relationships and a high prevalence of childhood trauma. Subjects with BPD reported experiencing more emotional abuse and intrafamilial sexual abuse, but more similarities than differences between probands and sisters were found. In multilevel analyses, personality traits of affective instability and impulsivity predicted DIB-R scores and SCL-90-R scores, above and beyond trauma. There were few relationships between childhood adversities and other measures of psychopathology. Sensitivity to adverse experiences, as reflected in the development of psychopathology, appears to be influenced by personality trait profiles.
Enterobius vermicularis infection and its risk factors among pre-school children in Taipei, Taiwan.
Chen, Kuang-Yao; Yen, Chuan-Min; Hwang, Kao-Pin; Wang, Lian-Chen
2017-06-29
The prevalence of pinworm infection is extremely low in Taipei, Taiwan. This population study was designed to determine the current status and the associated risk factors of this infection among pre-school children. Perianal swab specimens were obtained from the parents or guardians using a two-consecutive-day adhesive cellophane perianal swab kit. Information of family background, personal hygiene, and household sanitary conditions were collected by asking the parents or guardians to complete a questionnaire. Of 44,163 children, 0.21% was found to infect with pinworm. The positive rate was highest in Datong (0.59%) and Nangang (0.58%) Districts and lowest in Neihu District (0.02%). There was no significant difference in the rates by gender (boys 0.24% and girls 0.19%) or school (kindergartens 0.25% and nurseries 0.17%). Significantly higher positive rates were found in children having parent with lower educational level and elder brother(s)/sister(s). Children taking bath by themselves and those sleeping in bed with matting had significantly higher positive rates. Five significant independent predictors of pinworm infection were determined by multivariate analysis: having elder brother(s), having elder sister(s), infrequent washing hands after using toilet facilities, bathing without the help of family members, and sleeping on bed with matting. The prevalence of pinworm infection in the pre-school children of Taipei is extremely low and decreasing. Good hand washing habit should be an important preventive measure. Transmission of this infection in pre-school children may occur in the family through their school-age siblings. Copyright © 2017. Published by Elsevier B.V.
Edvardson, Simon; Korman, Stanley H; Livne, Amir; Shaag, Avraham; Saada, Ann; Nalbandian, Ruppen; Allouche-Arnon, Hyla; Gomori, J Moshe; Katz-Brull, Rachel
2010-01-01
Creatine and creatine phosphate provide storage and transmission of phosphate-bound energy in muscle and brain. Of the three inborn errors of creatine metabolism causing brain creatine depletion, l-arginine:glycine amidinotransferase (AGAT) deficiency has been described in only two families. We describe clinical and biochemical features, magnetic resonance spectroscopy (MRS) findings and response to creatine supplementation in two siblings with a novel mutation in the AGAT-encoding GATM gene. The sister and brother were evaluated at age 12 and 18years, respectively, because of mild mental retardation, muscle weakness and low weight. Extensive work-up had previously yielded negative results. Electron microscopy of the muscle revealed tubular aggregates and the activity of respiratory chain complexes was decreased in the muscle. Urine organic acid concentrations normalized to urine creatinine concentration were all increased, suggesting a creatine metabolism disorder. Brain MRS was remarkable for absence of creatine. Urine guanidinoacetate levels by tandem mass spectrometry were low, suggesting AGAT deficiency. GATM sequencing revealed a homozygous single nucleotide insertion 1111_1112insA, producing a frame-shift at Met-371 and premature termination at codon 376. Eleven months after commencing treatment with oral creatine monohydrate 100mg/kg/day, repeat MRI/MRS showed significantly increased brain creatine in the sister and a slight increase in the older brother. The parents' impression of improved strength and stamina was substantiated by increased post-treatment versus pre-treatment scores in the Vineland Adaptive Behavior Scale, straight-arm raising and timed up-and-go tests. Similarly, there was an apparent improvement in cognitive function, with significantly increased IQ-scores in the sister and marginal improvement in the brother. Copyright © 2010 Elsevier Inc. All rights reserved.
Patterson, P; McDonald, F E J; Butow, P; White, K J; Costa, D S J; Millar, B; Bell, M L; Wakefield, C E; Cohn, R J
2014-03-01
The current study sought to establish the psychometric properties of the revised Sibling Cancer Needs Instrument (SCNI) when completed by young people who have a brother or sister with cancer. The participants were 106 young people aged between 12 and 24 who had a living brother or sister diagnosed with any type or stage of cancer in the last 5 years. They were recruited from multiple settings. The initial step in determining the dimensional structure of the questionnaire was exploratory factor analysis and further assessment followed using Rasch analysis. Construct validity and test-retest reliability (n = 17) were also assessed. The final SCNI has 45 items and seven domains: information; practical assistance; "time out" and recreation; feelings; support (friends and other young people); understanding from my family; and sibling relationship. There was a reasonable spread of responses across the scale for every item. Rasch analysis results suggested that overall, respondents used the scale consistently. Support for construct validity was provided by the correlations between psychological distress and the SCNI domains. The internal consistency was good to excellent; Cronbach's alphas ranged from 0.78 to 0.94. The test-retest reliability of the overall measure is 0.88. The SCNI is the first measure of psychosocial unmet needs which has been developed for young people who have a brother or sister with cancer. The sound psychometric properties allow the instrument to be used with confidence. The measure will provide a substantial clinical benefit in highlighting the unmet needs of this population to assist with the prioritisation of targeted supportive care services and evaluating the impact of interventions targeted at siblings.
Kong, Hyejung Grace; Kim, Ock-Joo
2015-04-01
This study is about the Sisters of Charity of St. Joseph in New Orleans' Charity Hospital during the years between 1834 and 1860. The Sisters of Charity of St. Joseph was founded in 1809 by Saint Elizabeth Ann Bailey Seton (first native-born North American canonized in 1975) in Emmitsburg, Maryland. Seton's Sisters of Charity was the first community for religious women to be established in the United States and was later incorporated with the French Daughters of Charity of St. Vincent de Paul in 1850. A call to work in New Orleans' Charity Hospital in the 1830s meant a significant achievement for the Sisters of Charity, since it was the second oldest continuously operating public hospitals in the United States until 2005, bearing the same name over the decades. In 1834, Sister Regina Smith and other sisters were officially called to Charity Hospital, in order to supersede the existing "nurses, attendants, and servants," and take a complete charge of the internal management of Charity Hospital. The existing scholarship on the history of hospitals and Catholic nursing has not integrated the concrete stories of the Sisters of Charity into the broader histories of institutionalized medicine, gender, and religion. Along with a variety of primary sources, this study primarily relies on the Charity Hospital History Folder stored at the Daughters of Charity West Center Province Archives. Located in the "Queen city of the South," Charity Hospital was the center of the southern medical profession and the world's fair of people and diseases. Charity Hospital provided the sisters with a unique situation that religion and medicine became intertwined. The Sisters, as nurses, constructed a new atmosphere of caring for patients and even their families inside and outside the hospital, and built their own separate space within the hospital walls. As hospital managers, the Sisters of Charity were put in complete charge of the hospital, which was never seen in other hospitals. By
Zobor, Ditta; Balousha, Ghassan; Baumann, Britta; Wissinger, Bernd
2014-01-01
Retinitis pigmentosa (RP) is a heterogenous group of inherited retinal degenerations caused by mutations in at least 45 genes. Recently, the FAM161A gene was identified as the causative gene for RP28, an autosomal recessive form of RP. We performed a clinical and molecular genetic study of a consanguineous Palestinian family with two three siblings affected with retinitis pigmentosa. DNA samples were collected from the index patient, his father, his affected sister, and two non-affected brothers. DNA sample from the index was subjected to high resolution genome-wide SNP array. Assuming identity-by-descent in this consanguineous family we applied homozygosity mapping to identify disease causing genes. The index patient reported night blindness since the age of 20 years, followed by moderate disease progression with decrease of peripheral vision, the development of photophobia and later on reduced central vision. At the age of 40 his visual acuity was counting fingers (CF) for both eyes, color discrimination was not possible and his visual fields were severely constricted. Funduscopic examination revealed a typical appearance of advanced RP with optic disc pallor, narrowed retinal vessels, bone-spicule like pigmentary changes in the mid-periphery and atrophic changes in the macula. His younger affected brother (37 years) was reported with overall milder symptoms, while the youngest sister (21 years) reported problems only with night vision. Applying high-density SNP arrays we identified several homozygous genomic regions one of which included the recently identified FAM161A gene mutated in RP28-linked autosomal recessive RP. Sequencing analysis revealed the presence of a novel homozygous nonsense mutation, c.1003C>T/p.R335X in the index patient and the affected sister. We identified an RP28-linked RP family in the Palestinian population caused by a novel nonsense mutation in FAM161A. RP in this family shows a typical disease onset with moderate to rapid progression
Zobor, Ditta; Balousha, Ghassan; Baumann, Britta
2014-01-01
Purpose: Retinitis pigmentosa (RP) is a heterogenous group of inherited retinal degenerations caused by mutations in at least 45 genes. Recently, the FAM161A gene was identified as the causative gene for RP28, an autosomal recessive form of RP. Methods: We performed a clinical and molecular genetic study of a consanguineous Palestinian family with two three siblings affected with retinitis pigmentosa. DNA samples were collected from the index patient, his father, his affected sister, and two non-affected brothers. DNA sample from the index was subjected to high resolution genome-wide SNP array. Assuming identity-by-descent in this consanguineous family we applied homozygosity mapping to identify disease causing genes. Results: The index patient reported night blindness since the age of 20 years, followed by moderate disease progression with decrease of peripheral vision, the development of photophobia and later on reduced central vision. At the age of 40 his visual acuity was counting fingers (CF) for both eyes, color discrimination was not possible and his visual fields were severely constricted. Funduscopic examination revealed a typical appearance of advanced RP with optic disc pallor, narrowed retinal vessels, bone-spicule like pigmentary changes in the mid-periphery and atrophic changes in the macula. His younger affected brother (37 years) was reported with overall milder symptoms, while the youngest sister (21 years) reported problems only with night vision. Applying high-density SNP arrays we identified several homozygous genomic regions one of which included the recently identified FAM161A gene mutated in RP28-linked autosomal recessive RP. Sequencing analysis revealed the presence of a novel homozygous nonsense mutation, c.1003C>T/p.R335X in the index patient and the affected sister. Conclusion: We identified an RP28-linked RP family in the Palestinian population caused by a novel nonsense mutation in FAM161A. RP in this family shows a typical disease
Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes
Pongsavee, Malinee
2009-01-01
Background Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. Methods The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune cell proliferation (lymphocyte proliferation) and sister chromatid exchange in human chromosomes. The MTT assay and Sister Chromatid Exchange (SCE) technic were used in this experiment with the borax concentrations of 0.1, 0.15, 0.2, 0.3 and 0.6 mg/ml. Results It showed that the immune cell proliferation (lymphocyte proliferation) was decreased when the concentrations of borax increased. The borax concentration of 0.6 mg/ml had the most effectiveness to the lymphocyte proliferation and had the highest cytotoxicity index (CI). The borax concentrations of 0.15, 0.2, 0.3 and 0.6 mg/ml significantly induced sister chromatid exchange in human chromosomes (P < 0.05). Conclusion Borax had effects on immune cell proliferation (lymphocyte proliferation) and induced sister chromatid exchange in human chromosomes. Toxicity of borax may lead to cellular toxicity and genetic defect in human. PMID:19878537
Sister Mary Joseph's nodule as the first presenting sign of primary fallopian tube adenocarcinoma.
Kirshtein, Boris; Meirovitz, Mihai; Okon, Elimelech; Piura, Benjamin
2006-01-01
Umbilical metastasis (Sister Mary Joseph's nodule) is often the first sign of intraabdominal and/or pelvic carcinoma. We describe the fourth case reported in the literature of Sister Mary Joseph's nodule originating from fallopian tube carcinoma. In a 54-year-old woman, Sister Mary Joseph's nodule was unexpectedly detected during umbilical hernia repair. Subsequent laparoscopy revealed a 2-cm friable tumor located at the fimbriated end of right fallopian tube and 1-cm peritoneal implant in the pouch of Douglas. Laparoscopic bilateral adnexectomy and resection of the peritoneal implant were performed. Because frozen section examination revealed fallopian tube carcinoma, the procedure was continued with laparotomy including total abdominal hysterectomy, omentectomy, and pelvic lymph node sampling. Final diagnosis was stage IIIB fallopian tube carcinoma. The patient received postoperative adjuvant chemotherapy with single-agent carboplatin and has remained alive and with no evidence of disease. It is concluded that in cases of Sister Mary Joseph's nodule, laparoscopy can be a useful tool in the search of the primary tumor in the abdomen and/or pelvis. Laparoscopy can provide crucial information with respect to the location, size, and feasibility of optimal surgical resection of the intraabdominal and/or pelvic tumors.
Code of Federal Regulations, 2010 CFR
2010-01-01
...; (c) Parents; (d) Brothers and sisters, and spouses thereof; and (e) Any individual related by blood.... Leave donor means an employee whose voluntary written request for transfer of annual leave to the annual... from the annual leave accounts of one or more leave donors. Medical emergency means a medical condition...
8 CFR 207.7 - Derivatives of refugees.
Code of Federal Regulations, 2014 CFR
2014-01-01
... least 2 years; (3) A stepchild, if the marriage that created this relationship took place after the... marriage ceremony, and the marriage was not consummated (section 101(a)(35) of the Act); (5) A husband or... marriage for the purpose of evading immigration laws; and (6) A parent, sister, brother, grandparent...
8 CFR 207.7 - Derivatives of refugees.
Code of Federal Regulations, 2012 CFR
2012-01-01
... least 2 years; (3) A stepchild, if the marriage that created this relationship took place after the... marriage ceremony, and the marriage was not consummated (section 101(a)(35) of the Act); (5) A husband or... marriage for the purpose of evading immigration laws; and (6) A parent, sister, brother, grandparent...
8 CFR 207.7 - Derivatives of refugees.
Code of Federal Regulations, 2013 CFR
2013-01-01
... least 2 years; (3) A stepchild, if the marriage that created this relationship took place after the... marriage ceremony, and the marriage was not consummated (section 101(a)(35) of the Act); (5) A husband or... marriage for the purpose of evading immigration laws; and (6) A parent, sister, brother, grandparent...
ERIC Educational Resources Information Center
Schreiber, Meyer S., Ed.
Eleven papers from a June, 1984, seminar on siblings of mentally retarded and developmentally disabled persons are presented. The following papers are included: "An Adult Sibling Network: A Sharing of Experiences" (B. Cohen); "Siblings as Change Agents for Their Brothers and Sisters: Opportunity or Problem?" (G. Wolpert); "Adult Siblings: The…
11 CFR 100.93 - Travel by aircraft or other means of transportation.
Code of Federal Regulations, 2013 CFR
2013-01-01
... traveled or within seven (7) calendar days thereof. The payment rate must be determined by the time the... member” of a candidate is the father, mother, son, daughter, brother, sister, husband, wife, father-in... (d), not this section. (3) For the purposes of this section: (i) Campaign traveler means (A) Any...
ERIC Educational Resources Information Center
Sullivan, Christian Patrick
2011-01-01
With declining numbers of priests and religious sisters and brothers, principals and other Catholic school leaders need assistance in maintaining the Catholic identity and mission-related activities of their schools. One answer to the shortages of ordained priests has been employing lay campus ministers to help students in developing their faith…
11 CFR 100.93 - Travel by aircraft or other means of transportation.
Code of Federal Regulations, 2012 CFR
2012-01-01
... traveled or within seven (7) calendar days thereof. The payment rate must be determined by the time the... member” of a candidate is the father, mother, son, daughter, brother, sister, husband, wife, father-in... (d), not this section. (3) For the purposes of this section: (i) Campaign traveler means (A) Any...
Intergenerational Solidarity and Support between Adult Siblings
ERIC Educational Resources Information Center
Voorpostel, Marieke; Blieszner, Rosemary
2008-01-01
Using a Dutch national sample containing 1,259 triads (two siblings, one parent), we examined whether practical support and emotional support between siblings are enhanced by intergenerational solidarity and how this differs for brothers and sisters. Sibling support was affected by sibling dyad characteristics and by the relationship with the…
My Children Are Always Fighting. Working with Parents.
ERIC Educational Resources Information Center
Allen, Patsy
1994-01-01
Discusses techniques that teachers and parents can use to help young children cope with the birth of a new sibling and reduce fighting amongst siblings. Young children need to understand what is taking place, what is expected of them, and how they should interact with their brother or sister. (MDM)
Foundations for Emotional Intervention with Siblings of the Mentally Disabled
ERIC Educational Resources Information Center
Iriarte, Concha; Ibarrola-Garcia, Sara
2010-01-01
Introduction: It is very important to attend to the emotional experience of disabled persons' siblings. Instead of ignoring, minimizing or exaggerating their psychosocial needs, this article promotes thoughtful consideration of the wide range of emotional aspects--both positive and negative--that arise from having a disabled brother or sister.…
20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.
Code of Federal Regulations, 2010 CFR
2010-04-01
... (2) The surviving spouse or surviving divorced spouse or, where neither exists, the child of a... spouse, child, or parent, of a miner, where the deceased miner; (i) Was receiving benefits under section... entitlement to benefits applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and...
20 CFR 410.216 - “Good cause” for delayed filing of proof of support.
Code of Federal Regulations, 2010 CFR
2010-04-01
... support. 410.216 Section 410.216 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE... of support. (a) What constitutes “good cause.” Good cause may be found for failure to file proof of support within the 2-year period where the parent, brother, or sister establishes to the satisfaction of...
ERIC Educational Resources Information Center
Barnett, R. A.; Hunter, M.
2012-01-01
This study examined the adjustment of siblings of children with mental health problems. The participants had brothers or sisters receiving treatment at a Child and Adolescent Mental Health Service within the Hunter New England Health Service, New South Wales, Australia. Seventy-five siblings completed questionnaires on their self-concept, quality…
Helping as Coping by Siblings of the Disabled.
ERIC Educational Resources Information Center
Midlarsky, Elizabeth; Hannah, Mary Elizabeth
Research has shown that siblings can experience either negative or positive mental health outcomes as a result of having a brother or sister with disabilities. When maladjustment occurs, it is frequently attributed to the stress of excessive helping. This research-based paper proposes that siblings of children with disabilities, perceiving…
20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.
Code of Federal Regulations, 2011 CFR
2011-04-01
... spouse, child, or parent, of a miner, where the deceased miner; (i) Was receiving benefits under section... entitlement to benefits applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and... (2) The surviving spouse or surviving divorced spouse or, where neither exists, the child of a...
20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.
Code of Federal Regulations, 2012 CFR
2012-04-01
... spouse, child, or parent, of a miner, where the deceased miner; (i) Was receiving benefits under section... entitlement to benefits applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and... (2) The surviving spouse or surviving divorced spouse or, where neither exists, the child of a...
20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.
Code of Federal Regulations, 2013 CFR
2013-04-01
... spouse, child, or parent, of a miner, where the deceased miner; (i) Was receiving benefits under section... entitlement to benefits applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and... (2) The surviving spouse or surviving divorced spouse or, where neither exists, the child of a...
Code of Federal Regulations, 2013 CFR
2013-07-01
... the state where the autopsy will be performed, consists of a number of persons such as children, parents, brothers and sisters, etc., permission to perform an autopsy may be accepted when granted by the... the state where the autopsy will be performed, consists of a number of persons such as children...
Two Brothers, Two Cities: Music Education in Boston and Cincinnati from 1830-1844
ERIC Educational Resources Information Center
Lenzo, Terri Brown; Resta, Craig
2011-01-01
The birth of American music education is often attributed solely to Lowell Mason in Boston. His younger brother Timothy, however, was also active at the same time in Cincinnati. This study traces the roots of music education in both cities, but highlights the rarely cited accomplishments of Timothy Mason and his colleagues. Using historical…
The Irish Christian Brothers and the National Board of Education: Challenging the Myths
ERIC Educational Resources Information Center
McLaughlin, Denis
2008-01-01
For close to 170 years the general consensus from historians has been that Edmund Rice, who founded the Irish Christian Brothers in 1802, was an unenthusiastic applicant to the National Board of Education in Ireland in 1832 and later withdrew his schools because he believed his education was incompatible with the philosophy underpinning the…
Letters from a suicide: Van Gogh and his sister.
Lester, David
2010-04-01
An analysis of trends over a 3-yr. period in the letters of Vincent Van Gogh to his sister as the time of his suicide approached identified 8 trends, including an increase in words concerned with anxiety and words concerned with the past.
14. UPPER THREE SISTERS FALLS, LOOKING NORTHWEST Photocopy of photograph, ...
14. UPPER THREE SISTERS FALLS, LOOKING NORTHWEST Photocopy of photograph, 1930s National Park Service, National Capital Region files - Dumbarton Oaks Park, Thirty-second & R Streets Northwest, Washington, District of Columbia, DC
The Racial Integration of the Seven Sister Colleges.
ERIC Educational Resources Information Center
Perkins, Linda M.
1998-01-01
Although the number of African-American women who attended the elite Seven Sisters colleges prior to 1900 was small, these women were highly influential. Early integration is discussed for: (1) Wellesley College; (2) Radcliffe College; (3) Smith College; (4) Mount Holyoke College; (5) Bryn Mawr College; (6) Vassar College; and (7) Barnard College.…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kondoh, T.; Hayashi, K.; Matsumoto, T.
1995-10-09
We report two sisters in a family representing manifestations of Wiskott-Aldrich syndrome (WAS), an X-linked immunodeficiency disorder. An elder sister had suffered from recurrent infections, small thrombocytopenic petechiae, purpura, and eczema for 7 years. The younger sister had the same manifestations as the elder sister`s for a 2-year period, and died of intracranial bleeding at age 2 years. All the laboratory data of the two patients were compatible with WAS, although they were females. Sialophorin analysis with the selective radioactive labeling method of this protein revealed that in the elder sister a 115-KD band that should be specific for sialophorinmore » was reduced in quantity, and instead an additional 135-KD fragment was present as a main band. Polymerase chain reaction (PCR) analysis of the sialophorin gene and single-strand conformation polymorphism (SSCP) analysis of the PCR product demonstrated that there were no detectable size-change nor electrophoretic mobility change in the DNA from both patients. The results indicated that their sialophorin gene structure might be normal. Studies on the mother-daughter transmission of X chromosome using a pERT84-MaeIII polymorphic marker mapped at Xp21 and HPRT gene polymorphism at Xq26 suggested that each sister had inherited a different X chromosome from the mother. Two explanations are plausible for the occurrence of the WAS in our patients: the WAS in the patients is attributable to an autosomal gene mutation which may regulate the sialophorin gene expression through the WAS gene, or, alternatively, the condition in this family is an autosomal recessive disorder separated etiologically from the X-linked WAS. 17 refs., 6 figs., 1 tab.« less
A Thousand Lights [and] A Thousand Lights: Teacher and Parent Guide. Brothers Series.
ERIC Educational Resources Information Center
Benton, Hope
This book for children (ages 8 to 14) and the accompanying teacher/parent guide present the story of two brothers, one of whom has a severe hearing impairment, who climb up Mt. Fuji in Japan. Information on the disability is presented subtly and incidentally to encourage the reader to relate more personally and foster a deeper level of acceptance…
Brothers in Excellence: An Empowerment Model for the Career Development of African American Boys
ERIC Educational Resources Information Center
Grimmett, Marc A.
2010-01-01
The author describes Brothers in Excellence (BE), a conceptual model for understanding African American boys and helping them to be successful. BE addresses 3 domains of development proposed to be essential to the success of all African American boys: identity development, social development, and career development. (Contains 1 figure.)
ERIC Educational Resources Information Center
North Carolina Office of the State Auditor, Raleigh.
This report of the Office of the State Auditor in North Carolina details audit findings regarding allegations of misuse of Smart Start funds by Save Our Brothers, Inc. and the Liberty Chapel United Church of Christ. Save Our Brothers, Inc., a nonprofit agency, received two contracts totaling $46,327 from the Chatham County Partnership for Children…
Jarvie, Jennifer L; Johnson, Caitlin E; Wang, Yun; Wan, Yun; Aslam, Farhan; Athanasopoulos, Leonidas V; Pollin, Irene; Foody, JoAnne M
2011-01-01
There are substantial variations in cardiovascular disease (CVD) risk and outcomes among women. We sought to determine geographic variation in risk factor prevalence in a contemporary sample of U.S. women. Using 2008-2009 Sister to Sister (STS) free heart screening data from 17 U.S. cities, we compared rates of obesity (body mass index [BMI] ≥30 kg/m(2)), hypertension (HTN ≥140/90 mm Hg), low high-density lipoprotein cholesterol (HDL-C <40 mg/dL), and hyperglycemia (≥126 mg/dL) with national rates. In 18,892 women (mean age 49.8 ± 14.3 years, 37% black, 32% white, 14% Hispanic), compared to overall STS rates, significantly higher rates were observed for obesity in Baltimore (42.4%), Atlanta (40.0%), Dallas (37.9%), and Jacksonville (36.0%); for HTN in Atlanta (43.9%), Baltimore (42.5%), and New York (39.1%); for hyperglycemia in Jacksonville (20.3%), Philadelphia (18.1%), and Tampa (17.8%); and for HDL-C <40 mg/dL in Phoenix (37.4%), Dallas (26.5%), and Jacksonville (18.1%). Compared to national American Heart Association (AHA) 2010 update rates, most STS cities had higher rates of hyperglycemia and low HDL-C. In a large, community-based sample of women nationwide, this comprehensive analysis shows remarkable geographic variation in risk factors, which provides opportunities to improve and reduce a woman's CVD risk. Further investigation is required to understand the reasons behind such variation, which will provide insight toward tailoring preventive interventions to narrow gaps in CVD risk reduction in women.
Koehly, Laura M; Peters, June A; Kuhn, Natalia; Hoskins, Lindsey; Letocha, Anne; Kenen, Regina; Loud, Jennifer; Greene, Mark H
2008-08-01
We investigated the association between psychological distress and indices of social integration and communal coping among sisters from hereditary breast and ovarian cancer (HBOC) families. Sixty-five sisters from 31 HBOC families completed the Brief Symptom Inventory-18 and the Colored Eco-Genetic Relationship Map, which identified members of participants' social support networks. Hierarchical linear models were used for all analyses to account for the clustering of sisters within families. Intra-family correlation coefficients suggested that sisters shared perceptions of breast cancer risk and worry, but not ovarian cancer risk and worry. Further, sisters demonstrated shared levels of anxiety and somatization, but not depressive symptoms. Communal coping indices quantifying shared support resources were negatively related to anxiety and somatization. The number of persons with whom cancer risk information was shared exhibited a positive trend with somatization. Social integration, as measured by the size of participants' emotional support network, was negatively associated with anxiety. Lower depression scores were observed among participants with more persons playing multiple support roles and fewer persons providing tangible assistance. Understanding how support relationships impact well-being among persons adjusting to HBOC risk, and the particular role of family in that process, will facilitate developing appropriate management approaches to help cancer-prone families adjust to their cancer risk.
The Effect of Stresses and Challenges on ’A’ School Students’ Performance and Commitment.
1982-01-01
ethnic background, birth order , and size of home town. b. Personality measures were assessed using 14 scales from Gough and Heilbrun’s (1965) 300-item...sisters do yott have _ brother sL-ters 11. hat. is your birth order ? (firsc born, the third born, etc.) 12. Please circle the ausber which best
Code of Federal Regulations, 2010 CFR
2010-07-01
... employee suffering the loss or damage, or in the event of his or her death, by the surviving spouse, children, father or mother or both, or brothers or sisters or both. Claims of survivors shall be settled... loss or damage occurred and the circumstances surrounding such loss or damage, together with the...
Code of Federal Regulations, 2012 CFR
2012-07-01
... employee suffering the loss or damage, or in the event of his or her death, by the surviving spouse, children, father or mother or both, or brothers or sisters or both. Claims of survivors shall be settled... loss or damage occurred and the circumstances surrounding such loss or damage, together with the...
Code of Federal Regulations, 2013 CFR
2013-07-01
... employee suffering the loss or damage, or in the event of his or her death, by the surviving spouse, children, father or mother or both, or brothers or sisters or both. Claims of survivors shall be settled... loss or damage occurred and the circumstances surrounding such loss or damage, together with the...
Code of Federal Regulations, 2014 CFR
2014-07-01
... employee suffering the loss or damage, or in the event of his or her death, by the surviving spouse, children, father or mother or both, or brothers or sisters or both. Claims of survivors shall be settled... loss or damage occurred and the circumstances surrounding such loss or damage, together with the...
Code of Federal Regulations, 2011 CFR
2011-07-01
... employee suffering the loss or damage, or in the event of his or her death, by the surviving spouse, children, father or mother or both, or brothers or sisters or both. Claims of survivors shall be settled... loss or damage occurred and the circumstances surrounding such loss or damage, together with the...
Public, Private, and Home School Children's Views of Forgiveness and Retribution in "Cinderella."
ERIC Educational Resources Information Center
Knafle, June D.; Wescott, Alice Legenza
Fifth Graders (N=626) from public, Catholic, Christian, and home schools reacted to values of forgiveness versus retribution in the two main versions of "Cinderella" by choosing which ending they preferred for themselves, for a 4-year old sister, and for a 4-year old brother. Girls preferred the forgiveness ending for themselves…
Sibling Relationships: Parent-Child Agreement and Contributions of Siblings with and without ASD
ERIC Educational Resources Information Center
Braconnier, Megan L.; Coffman, Marika C.; Kelso, Nicole; Wolf, Julie M.
2018-01-01
Research on the experiences of siblings of individuals with ASD and the quality of their sibling relationships has yielded mixed results. The present study examined the significance of parent- versus child-report of both positive and negative behaviors exhibited by siblings and their brothers and sisters with ASD within sibling dyads. Findings…
ERIC Educational Resources Information Center
Tozer, Rosemary; Atkin, Karl
2015-01-01
Background: The potential of adult siblings to offer long-term support to a brother or sister with autism is rarely realized. To understand this, our study explores the expectations of social care among adult siblings. Method: Using qualitative interviews, we spoke to 21 adult siblings about their family relationships and engagement with service…
ERIC Educational Resources Information Center
Giallo, R.; Gavidia-Payne, S.
2006-01-01
Background: Siblings adjust to having a brother or sister with a disability in diverse ways. This study investigated a range of child, parent and family factors as predictors of sibling adjustment outcomes. Methods: Forty-nine siblings (aged 7-16 years) and parents provided information about (1) sibling daily hassles and uplifts; (2) sibling…
ERIC Educational Resources Information Center
Bitsika, Vicki; Sharpley, Christopher F.; Mailli, Rebecca
2015-01-01
The influence of gender, age, Psychological resilience and family interaction factors upon generalised anxiety disorder (GAD) and major depressive disorder (MDD) was investigated in 75 non-autism spectrum disorder (NASD) siblings who had a brother or sister with an autism spectrum disorder (ASD). GAD and MDD were much more prevalent than in…
Ambivalence in Adult Sibling Relationships.
ERIC Educational Resources Information Center
Bedford, Victoria H.
1989-01-01
Examined gender and developmental differences in awareness of underlying feelings about subjects' age-near, same-sex sibling in 60 child-rearing and empty nest subjects. Found that women seemed to be more aware of their underlying feelings toward sisters than were men toward brothers, but valence of feelings was life phase-specific. (TE)
32 CFR 1642.1 - Purpose; definitions.
Code of Federal Regulations, 2013 CFR
2013-07-01
... this part. (1) The term dependent shall apply to the wife, child, parent, grandparent, brother or sister of a registrant. (2) The term child includes an unborn child, a stepchild, a foster child or a legally adopted child, who is legitimate or illegitimate, but shall not include any person 18 years of age...
32 CFR 1642.1 - Purpose; definitions.
Code of Federal Regulations, 2012 CFR
2012-07-01
... this part. (1) The term dependent shall apply to the wife, child, parent, grandparent, brother or sister of a registrant. (2) The term child includes an unborn child, a stepchild, a foster child or a legally adopted child, who is legitimate or illegitimate, but shall not include any person 18 years of age...
32 CFR 1642.1 - Purpose; definitions.
Code of Federal Regulations, 2014 CFR
2014-07-01
... this part. (1) The term dependent shall apply to the wife, child, parent, grandparent, brother or sister of a registrant. (2) The term child includes an unborn child, a stepchild, a foster child or a legally adopted child, who is legitimate or illegitimate, but shall not include any person 18 years of age...
Degortes, Daniela; Zanetti, Tatiana; Tenconi, Elena; Santonastaso, Paolo; Favaro, Angela
2014-07-01
Although there is evidence that childhood perfectionistic traits predate the onset of eating disorders, few studies to date have examined the prevalence and clinical correlates of these traits in patients with anorexia nervosa (AN) and their unaffected sisters. The aim of this work was to study the prevalence of childhood obsessive-compulsive traits in patients with lifetime AN, their unaffected sisters and healthy women. A total of 116 AN patients, 32 healthy sisters and 119 controls were assessed by the EATATE Interview to assess traits such as perfectionism, inflexibility, rule-bound traits, drive for order and symmetry, and excessive doubt and cautiousness. Both self-report and maternal reports were collected. AN patients reported more childhood obsessive-compulsive traits than their healthy sisters and controls. In contrast, no differences between healthy controls and unaffected sisters emerged. In patients with AN, a dose-response relationship was found between the number of childhood obsessive-compulsive traits and psychopathology, including body image distortion, thus indicating that these traits are an important feature to be considered in assessing and treating eating disorders. Copyright © 2014 John Wiley & Sons, Ltd and Eating Disorders Association.
CNGA3 mutations in two United Arab Emirates families with achromatopsia.
Ahuja, Yachna; Kohl, Susanne; Traboulsi, Elias I
2008-07-10
ACHROMATOPSIA RESULTS FROM MUTATIONS IN ONE OF THREE GENES: cyclic nucleotide-gated channel, alpha-3 (CNGA3); cyclic nucleotide-gated channel, beta-3 (CNGB3); and guanine nucleotide-binding protein, alpha-transducing activity polypeptide 2 (GNAT2). We report the responsible mutations in two United Arab Emirates families who have this autosomal recessive disease. Clinical examinations were performed in seven patients from three nuclear families. Molecular genetic testing for common CNGA3 and CNGB3 mutations was undertaken using standard protocols. All patients were extremely light sensitive and had reduced visual acuity and no color perception. Fundus examinations did not show any visible abnormalities. After further pedigree analysis, two of the families were found to be linked through the paternal line. Two mutations in CNGA3 were identified: Arg283Trp and Gly397Val. Family A, the larger pedigree, had one branch in which two sisters and one brother were homozygous for the Gly397Val mutation and another branch in which a brother and sister were compound heterozygous for both aforenamed mutations. Family B, however, only had two brothers who were homozygous for the Arg283Trp mutation. Achromatopsia in these two United Arab Emirates families results from two different mutations in CNGA3. Two branches of the same pedigree had individuals with both homozygous and compound heterozygous disease, demonstrating a complex molecular pathology in this large family.
8. STREAMSIDE PATH NEAR MIDDLE OF THREE SISTERS FALLS, LOOKING ...
8. STREAM-SIDE PATH NEAR MIDDLE OF THREE SISTERS FALLS, LOOKING WEST Photocopy of photograph, 1930s National Park Service, National Capital Region files - Dumbarton Oaks Park, Thirty-second & R Streets Northwest, Washington, District of Columbia, DC
Sibling Relationships and Adjustment of Children with Disabled Brothers and Sisters.
ERIC Educational Resources Information Center
McHale, Susan M.; Gamble, Wendy C.
1987-01-01
Examination of children with disabled siblings reveals that nondisabled children may treat their siblings more kindly and spend more time caring for them than do children with nondisabled siblings. Their experiences may produce more worries and anxieties; however, they also may develop more tolerance and humanitarian concerns. (Author/BJV)
20 CFR 410.340 - Determination of relationship; parent, brother, or sister.
Code of Federal Regulations, 2011 CFR
2011-04-01
... COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Relationship and... domiciled (see § 410.392) at the time of his death would find, under the law they would apply in determining...
20 CFR 410.214 - Conditions of entitlement; parent, brother, or sister.
Code of Federal Regulations, 2011 CFR
2011-04-01
... MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Requirements for Entitlement... years after the miner's death, whichever is later, or it is shown to the satisfaction of the... chapter), at the time of the miner's death. (c) In addition to the requirements set forth in paragraphs (a...
When Your Brother or Sister Has Cancer: A Guide for Teens
... can be given as pills, through an injection (shot), or through an intravenous (IV) line. It is ... research study that tests how well new medical approaches work in people. These studies test new methods ...
ERIC Educational Resources Information Center
Cibes, Margaret; Greenwood, James
2016-01-01
Media Clips appears in every issue of Mathematics Teacher, offering readers contemporary, authentic applications of quantitative reasoning based on print or electronic media. This issue features "How Big is Too Big?" (Margaret Cibes and James Greenwood) in which students are asked to analyze the data and tables provided and answer a…
Clinical Design Sciences: A View from Sister Design Efforts.
ERIC Educational Resources Information Center
Zaritsky, Raul; Kelly, Anthony E.; Flowers, Woodie; Rogers, Everett; O'Neill, Patrick
2003-01-01
Asserts that the social sciences are clinical-like endeavors, and the way that "sister" fields discover and validate their results may inform research practice in education. Describes three fields of design that confront similar societal demands for improvement (engineering product design, research on the diffusion of innovations, and…
My Brother as "Problem": Neoliberal Governmentality and Interventions for Black Young Men and Boys
ERIC Educational Resources Information Center
Dumas, Michael J.
2016-01-01
In this article, the author argues that the Obama Administration's My Brother's Keeper (MBK) initiative serves as an exemplar of neoliberal governmentality, in which Black young men and boys are constructed as essentially damaged, as problems in need of a technocratic public--private solution. More than simply an ideological imposition from above…
Big Brother Is Not Watching You Act
Rep. Grayson, Alan [D-FL-9
2014-01-15
House - 03/20/2014 Referred to the Subcommittee on Crime, Terrorism, Homeland Security, and Investigations. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Costes, V; Medioni, D; Durand, L; Sarran, N; Marguerite, G; Baldet, P
1997-03-01
We report a case of congenital cervical rhabdoid tumor with association of a medulloblastoma in a brother. The immunohistochemical features of this tumor are compatible with a neuroectodermal differentiation (MIC 2+, Leu 7+). Extrarenal rhabdoid tumors share a common morphology but do not represent a single entity with only one histogenesis. Most of them are now considered to be of neuroectodermal origin. In our case, the association with a medulloblastoma in a brother seems to confirm this concept.
Koehly, Laura M.; Peters, June A.; Kuhn, Natalia; Hoskins, Lindsey; Letocha, Anne; Kenen, Regina; Loud, Jennifer; Greene, Mark H.
2011-01-01
Objective We investigated the association between psychological distress and indices of social integration and communal coping among sisters from hereditary breast and ovarian cancer (HBOC) families. Sample and methods Sixty-five sisters from 31 HBOC families completed the Brief Symptom Inventory-18 and the Colored Eco-Genetic Relationship Map, which identified members of participants’ social support networks. Hierarchical linear models were used for all analyses to account for the clustering of sisters within families. Results Intra-family correlation coefficients suggested that sisters shared perceptions of breast cancer risk and worry, but not ovarian cancer risk and worry. Further, sisters demonstrated shared levels of anxiety and somatization, but not depressive symptoms. Communal coping indices quantifying shared support resources were negatively related to anxiety and somatization. The number of persons with whom cancer risk information was shared exhibited a positive trend with somatization. Social integration, as measured by the size of participants’ emotional support network, was negatively associated with anxiety. Lower depression scores were observed among participants with more persons playing multiple support roles and fewer persons providing tangible assistance. Conclusion Understanding how support relationships impact well-being among persons adjusting to HBOC risk, and the particular role of family in that process, will facilitate developing appropriate management approaches to help cancer-prone families adjust to their cancer risk. Published in 2008 by John Wiley & Sons Ltd. PMID:18688790
Yildirim, Ali; Ozer, Erdal; Bozkurt, Hasan; Ozsoy, Sait; Enginyurt, Ozgur; Evcuman, Durmus; Yilmaz, Riza; Kuyucu, Yunus Emre
2014-04-26
Incest is defined as any sexual activity between close blood relatives including step relatives and family members who are forbidden by law to marry. It is a problem that can be seen in all the social classes in developed and undeveloped societies. The World Health Organization classifies this problem as a silent health emergency. Father-daughter incest is reported to be the most common incest type followed by the other types like brother-sister, sister-sister and mother-son incest. Subjects for this study were recruited from a sample of incest cases referred to Forensic Medicine Department of Gaziosmanpasa University Medical Faculty Hospital between 2008 and 2012. Data involved social and demographic characteristics and clinical features of victims, perpetrators and the families. The ethical committee of the faculty of medicine approved the study. The study sample consisted of 43 incest cases (36 females and 7 males) with an age rage 4-40 years. Two third of the victims were under 18 years old. All perpetrators were males. Father - daughter incest (34.9%) was found to be most common incest type followed by brother - sister incest (14%). 75% of the perpetrators were family members and relatives with consanguinity while 25% of them were not consanguineous but faithful and intimate relatives to victims. Increasing awareness about incest and its damaging effects is so important and clinicians should keep in mind sexual abuse or incest when examining the risky population. Multidisciplinary approach is necessary for determining short term or long term results and preventing the negative consequences of incest.
NASA Astrophysics Data System (ADS)
Playter, R.; Buehler, M.; Raibert, M.
2006-05-01
BigDog's goal is to be the world's most advanced quadruped robot for outdoor applications. BigDog is aimed at the mission of a mechanical mule - a category with few competitors to date: power autonomous quadrupeds capable of carrying significant payloads, operating outdoors, with static and dynamic mobility, and fully integrated sensing. BigDog is about 1 m tall, 1 m long and 0.3 m wide, and weighs about 90 kg. BigDog has demonstrated walking and trotting gaits, as well as standing up and sitting down. Since its creation in the fall of 2004, BigDog has logged tens of hours of walking, climbing and running time. It has walked up and down 25 & 35 degree inclines and trotted at speeds up to 1.8 m/s. BigDog has walked at 0.7 m/s over loose rock beds and carried over 50 kg of payload. We are currently working to expand BigDog's rough terrain mobility through the creation of robust locomotion strategies and terrain sensing capabilities.
Yilmaz, Murat; Bukan, Neslihan; Ersoy, Reyhan; Karakoç, Ayhan; Yetkin, Ilhan; Ayvaz, Göksun; Cakir, Nuri; Arslan, Metin
2005-09-01
The aim of the present study was to evaluate insulin resistance (IR), glucose tolerance status and cardiovascular risk factors in first degree relatives of patients with polycystic ovary syndrome (PCOS). A total of 120 family members [Mothers(PCOS) (n = 40), Fathers(PCOS) (n = 38), Sisters(PCOS) (n = 25) and Brothers(PCOS) (n = 17)] of 55 patients with PCOS and 75 unrelated healthy control subjects without a family history of diabetes or PCOS (four age- and weight-matched subgroups, i.e. Control(Mothers), Control(Fathers), Control(Sisters) and Control(Brothers)) were studied. IR was assessed by homeostatic model assessment (HOMA IR), log HOMA, insulin sensivity index (ISI), the quantitative insulin sensitivity check index (QUICKI) and area under the curve for insulin during the oral glucose tolerance test (AUCI, AUCG) in with normal glucose tolerance (NGT) subjects and controls. Serum adiponectin, resistin, homocysteine and lipid levels were measured. The prevalence of any degree of glucose intolerance was 40% in Mothers(PCOS) and 52% in Fathers(PCOS). In total, six (15%) glucose tolerance disorders were identified in the Control(Mothers) and Control(Fathers) in first degree relatives of control subjects. The first degree relatives of PCOS patients had significantly higher serum fasting insulin, HOMA-IR, Log HOMA and AUCI levels in all subgroups than the control subjects. The control subjects had significantly elevated QUCKI, ISI levels and serum adiponectin levels compared to the first degree relatives of PCOS subjects in all subgroups. The serum Hcy and resistin levels increased significantly in both Fathers(PCOS) and Mothers(PCOS) groups but not Brothers(PCOS) and Sister(PCOS). The results of the present study support the finding that the first degree relatives of PCOS patients carry an increased risk of cardiovascular disease, as do PCOS patients.
7. STREAMSIDE PATH BETWEEN THREE BRIDGE FALLS AND THREE SISTERS ...
7. STREAM-SIDE PATH BETWEEN THREE BRIDGE FALLS AND THREE SISTERS FALLS, LOOKING WEST Photocopy of photograph, 1930s National Park Service, National Capital Region files - Dumbarton Oaks Park, Thirty-second & R Streets Northwest, Washington, District of Columbia, DC
Code of Federal Regulations, 2010 CFR
2010-01-01
..., brother, sister, aunt, uncle, grandparent, grandchild, niece, or nephew. In-house expenses. In-house... office). Rural and rural area. (1) For fiscal year 1999, the terms “rural” and “rural area” mean a city.... (2) For later fiscal years, the terms “rural” and “rural area” mean a city, town, or unincorporated...
Long-Term Follow-up Study of Children Developmentally Retarded by Early Environmental Deprivation.
ERIC Educational Resources Information Center
Fujinaga, Tamotsu; And Others
This paper reports on a 14-year follow-up study of two developmentally retarded Japanese children, a brother and sister, who had been kept shut up in a small shack before being rescued (at ages 5 and 6 respectively). Following birth they consistently suffered malnutrition, maternal deprivation, social isolation from adults, language deprivation,…
Siblings of Individuals with Autism or Down Syndrome: Effects on Adult Lives
ERIC Educational Resources Information Center
Orsmond, Gael. I.; Seltzer, M. M.
2007-01-01
Background: In this study, we examine instrumental and affective involvement in the sibling relationship for adults who have a brother or sister with an autism spectrum disorder (ASD) or Down syndrome (DS). We ask three research questions: (1) How do adult siblings of individuals with ASD differ from siblings of individuals with DS in their…
Coping by Siblings of the Handicapped: The Role of Altruistic Helping.
ERIC Educational Resources Information Center
Midlarsky, Elizabeth; Hannah, Mary Elizabeth
The paper examines the possible role of siblings of handicapped children in helping or caretaking. A review of the literature is performed as a basis for proposing that there are circumstances in which intrinsically motivated, or altruistic, helping may be a more adaptive approach to coping with a handicapped brother or sister than other…
The Vocation of the Catholic Educator. The NCEA Catholic Educational Leadership Monograph Series.
ERIC Educational Resources Information Center
Jacobs, Richard M.
The decline in the number of Catholic sisters, brothers, and priests serving as teachers and administrators in Catholic schools has been accompanied by an increase in the number of men and women educators from the laity. This handbook presents guidelines for preparing the laity to teach and administer effectively in Catholic schools. Specifically,…
An Analysis of Tactical Military Airlift
1997-09-01
an officer; Ashley Donoho and Walinda Enoch, my brother and sister; and Shane Dies, my best friend, who taught me to play guitar - a hobby that has...1969: 29). The book Hell in a Very Small Place, a classic history of Dienbienphu by Bernard B. Fall, made many people in the United States skeptical
An illness in the family: Dr. Maude Abbott and her sister, Alice Abbott.
Brookes, Barbara
2011-01-01
This paper explores Maude Abbott's internationally significant career in medicine and her parallel commitment to caring for her sister, Alice Abbott. An examination of Abbott's life reveals the difficulties faced by an ambitious Canadian woman in medicine from the 1890s to the 1920s; difficulties compounded by caring for a sister with a mental illness. The Abbott archive suggests that it was far more difficult for a woman doctor to make the kind of sharp distinction between public and private life that might be expected of professional men.
Chinese herbal medicine, sibship, and blood lead in children.
Cheng, T J; Wong, R H; Lin, Y P; Hwang, Y H; Horng, J J; Wang, J D
1998-08-01
Risk factors for increased blood lead concentration (BPb) has been investigated. However, the effect of sibship and Chinese herbal medicine on BPb has not been systematically studied. In this study BPb data from voluntary testing was used to determine if Chinese herbal medicine and sibship were associated with BPb. 319 children aged 1-7 were tested for BPb. Meanwhile, parents were interviewed to obtain information including consumption of Chinese herbal medicine, living environment, lifestyle, and sibship of the children tested. The mean (SD) BPb of 319 preschool children was 4.4 (2.4) micrograms/dl. The consumption of Ba-baw-san (a Chinese herbal medicine) was significantly associated with increased BPb in children (p = 0.038). Further multivariate regression analysis of BPb in 50 pairs of siblings showed the factors of being brothers explained 75% of variation for BPb, and being sisters and brother-sister explained 51% and 41% of variation respectively. Chinese herbal medicine and children's play patterns within the family expressed in different types of sibship are the main determinants of low concentrations of BPb in preschool children of Taiwan.
Sin, Jacqueline; Moone, Nicki; Harris, Paul; Scully, Elizabeth; Wellman, Nigel
2012-02-01
Despite recent focus on developing family-inclusive services to meet the needs of young people with first-episode psychosis, the needs of their siblings are often overlooked. This study explored the experiences and needs of siblings of young adults with first-episode psychosis receiving support from two Early Intervention in Psychosis Services in South-East England. Thirty-one siblings aged 11-35 years, were given a semi-structured interview to gather their perspectives and accounts of their lived experiences. The resultant rich qualitative data was analysed using responsive-reader and framework methods. Six themes were identified: siblings' roles and involvement; emotions; impact on relationships; coping patterns; resilience; and siblings' service needs. All participants had been greatly affected by the onset of the psychosis in their brother or sister. Most siblings did not identify themselves as carers, although most played a significant part in their brother's or sister's life. Participants wanted dynamic, robust and accessible services, especially information and peer support to meet their needs. © 2011 Blackwell Publishing Asia Pty Ltd.
Rosser, Neil; Kozak, Krzysztof M; Phillimore, Albert B; Mallet, James
2015-06-30
Sympatric speciation is today generally viewed as plausible, and some well-supported examples exist, but its relative contribution to biodiversity remains to be established. We here quantify geographic overlap of sister species of heliconiine butterflies, and use age-range correlations and spatial simulations of the geography of speciation to infer the frequency of sympatric speciation. We also test whether shifts in mimetic wing colour pattern, host plant use and climate niche play a role in speciation, and whether such shifts are associated with sympatry. Approximately a third of all heliconiine sister species pairs exhibit near complete range overlap, and analyses of the observed patterns of range overlap suggest that sympatric speciation contributes 32%-95% of speciation events. Müllerian mimicry colour patterns and host plant choice are highly labile traits that seem to be associated with speciation, but we find no association between shifts in these traits and range overlap. In contrast, climatic niches of sister species are more conserved. Unlike birds and mammals, sister species of heliconiines are often sympatric and our inferences using the most recent comparative methods suggest that sympatric speciation is common. However, if sister species spread rapidly into sympatry (e.g. due to their similar climatic niches), then assumptions underlying our methods would be violated. Furthermore, although we find some evidence for the role of ecology in speciation, ecological shifts did not show the associations with range overlap expected under sympatric speciation. We delimit species of heliconiines in three different ways, based on "strict and " "relaxed" biological species concepts (BSC), as well as on a surrogate for the widely-used "diagnostic" version of the phylogenetic species concept (PSC). We show that one reason why more sympatric speciation is inferred in heliconiines than in birds may be due to a different culture of species delimitation in the two
Blanchard, Ray
2007-12-01
Frisch and Hviid (2006) recently reported a study of variables that predicted heterosexual and homosexual marriage in a national cohort of Danish men and women. They found no evidence that older brothers increase the probability that a man will legally marry another man. They concluded that their data raise questions about the universality of the widely confirmed finding that older brothers increase the probability that a man will be sexually oriented towards other men (the fraternal birth order effect). In the present article, Frisch and Hviid's data were reanalyzed using one of the procedures that have been used in prior studies of fraternal birth order. The results showed that the sex ratio of older brothers to older sisters was significantly higher than the expected value of 106 in all four of their study groups (heterosexually married men, homosexually married men, heterosexually married women, and homosexually married women). In contrast, the sex ratio of younger brothers to younger sisters approximated 106 in all four groups. According to this analysis, the only group whose data resembled data from previous studies was the homosexually married males. The writer concluded that one cannot interpret findings about the correlates of heterosexual and homosexual marriage as if they were findings about the correlates of heterosexual and homosexual orientation, and that this is underscored by comparing the markedly different older-sibling sex ratios obtained from heterosexually married persons (in the Danish study) and those obtained from heterosexually oriented persons (in previous studies). It is unclear what implications, if any, Frisch and Hviid's findings have for the study of sexual orientation in general.
Nursing Needs Big Data and Big Data Needs Nursing.
Brennan, Patricia Flatley; Bakken, Suzanne
2015-09-01
Contemporary big data initiatives in health care will benefit from greater integration with nursing science and nursing practice; in turn, nursing science and nursing practice has much to gain from the data science initiatives. Big data arises secondary to scholarly inquiry (e.g., -omics) and everyday observations like cardiac flow sensors or Twitter feeds. Data science methods that are emerging ensure that these data be leveraged to improve patient care. Big data encompasses data that exceed human comprehension, that exist at a volume unmanageable by standard computer systems, that arrive at a velocity not under the control of the investigator and possess a level of imprecision not found in traditional inquiry. Data science methods are emerging to manage and gain insights from big data. The primary methods included investigation of emerging federal big data initiatives, and exploration of exemplars from nursing informatics research to benchmark where nursing is already poised to participate in the big data revolution. We provide observations and reflections on experiences in the emerging big data initiatives. Existing approaches to large data set analysis provide a necessary but not sufficient foundation for nursing to participate in the big data revolution. Nursing's Social Policy Statement guides a principled, ethical perspective on big data and data science. There are implications for basic and advanced practice clinical nurses in practice, for the nurse scientist who collaborates with data scientists, and for the nurse data scientist. Big data and data science has the potential to provide greater richness in understanding patient phenomena and in tailoring interventional strategies that are personalized to the patient. © 2015 Sigma Theta Tau International.
Creatine Transporter Deficiency in Two Brothers with Autism Spectrum Disorder.
Aydin, Halil Ibrahim
2018-01-15
Creatine transporter deficiency (CTD) is a treatable, X-linked, inborn error of metabolism. Two brothers with autism spectrum disorder were diagnosed with CTD at the ages of 17 and 12 years. Both were found to have a previously reported hemizygous p.408delF (c.1216_1218delTTC) deletion mutation. Both patients were given creatine monohydrate, L-arginine, L-glycine and S-adenosylmethionine, which partially improved the behavioral problems. Serum creatinine levels, creatine peak at brain MR spectroscopy or creatine/creatinine ratio in urine should be evaluated to identify CTD in children with autistic behavior and language disorders.
Negative pressure pulmonary oedema: a rare case report of two brothers.
Jaafarpour, Molouk; Khajavikhan, Javaher; Khani, Ali
2013-10-01
Negative Pressure Pulmonary O/Edema (NPPE) is potentially life-threatening and it is a general anaesthesia side effect. We are mentioning a rare case report of two brothers who were referred to our hospital for elective surgeries (varicocele and septoplasty) in a 3 years period. Both of them were athletes and their coagulation factors were disturbed after surgeries. Pulmonary oedema was healed after treating it by reintubation, mechanical ventilation by Positive End-Expiratory Pressure (PEEP), diuretics, morphine, Fresh Frozen Plasma (FFP) and liquid bounding.
Negative Pressure Pulmonary Oedema: A Rare Case Report of Two Brothers
Jaafarpour, Molouk; Khajavikhan, Javaher; Khani, Ali
2013-01-01
Negative Pressure Pulmonary O/Edema (NPPE) is potentially life-threatening and it is a general anaesthesia side effect. We are mentioning a rare case report of two brothers who were referred to our hospital for elective surgeries (varicocele and septoplasty) in a 3 years period. Both of them were athletes and their coagulation factors were disturbed after surgeries. Pulmonary oedema was healed after treating it by reintubation, mechanical ventilation by Positive End-Expiratory Pressure (PEEP), diuretics, morphine, Fresh Frozen Plasma (FFP) and liquid bounding. PMID:24298513
Stelter, Rebecca L; Kupersmidt, Janis B; Stump, Kathryn N
2018-04-15
Implementation of research- and safety-based program practices enhance the longevity of mentoring relationships, in general; however, little is known about how mentoring programs might support the relationships of mentees in foster care. Benchmark program practices and Standards in the Elements of Effective Practice for Mentoring, 3rd Edition (MENTOR, 2009) were assessed in the current study as predictors of match longevity. Secondary data analyses were conducted on a national agency information management database from 216 Big Brothers Big Sisters agencies serving 641 youth in foster care and 70,067 youth not in care from across the United States (Mean = 11.59 years old at the beginning of their matches) in one-to-one, community-based (55.06%) and school- or site-based (44.94%) matches. Mentees in foster care had shorter matches and matches that were more likely to close prematurely than mentees who were not in foster care. Agency leaders from 32 programs completed a web-based survey describing their policies and practices. The sum total numbers of Benchmark program practices and Standards were associated with match length for 208 mentees in foster care; however, neither predicted premature match closure. Results are discussed in terms of how mentoring programs and their staff can support the mentoring relationships of high-risk youth in foster care. © Society for Community Research and Action 2018.
Chan, Christian S.; Rhodes, Jean E.; Howard, Waylon J.; Lowe, Sarah R.; Schwartz, Sarah E.O.; Herrera, Carla
2013-01-01
This study explores the pathways through which school-based mentoring relationships are associated with improvements in elementary and high school students’ socio-emotional, academic, and behavioral outcomes. Participants in the study (N=526) were part of a national evaluation of the Big Brothers Big Sisters school-based mentoring programs, all of whom had been randomly assigned to receive mentoring at their schools over the course of one academic year. Students were assessed at the beginning and end of the school year. The results of structural equation modeling showed that mentoring relationship quality, as measured by the Youth-Centered Relationship scale and the Youth’s Emotional Engagement scale, was significantly associated with positive changes in youths’ relationships with parents and teachers, as measured by subscales of the Inventory of Parent and Peer Attachment, the Teacher Relationship Quality scale, and the Hemingway Measure of Adolescent Connectedness. Higher quality relationships with parents and teachers, in turn, were significantly associated with better youth outcomes, including self-esteem, academic attitudes, prosocial behaviors, and misconduct. The effect sizes of the associations ranged from 0.12 to 0.52. Mediation analysis found that mentoring relationship quality was indirectly associated with some of the outcomes through its association with improved parent and teacher relationships. Implications of the findings for theory and research are discussed. PMID:23375177
Relationship of order and number of siblings to perceived parental attitudes in childhood.
Kitamura, T; Sugawara, M; Shima, S; Toda, M A
1998-06-01
Despite the increasingly recognized link between perceived parenting behavior and the onset of psychopathology in adults, studies of the possible determinants of perceptions of parenting behavior are rare. In a sample of 1,145 pregnant Japanese women, correlations were examined between the numbers and sexes of siblings and perceived rearing practices, as rated by the Parental Bonding Instrument (PBI; Parker, Tupling, & Brown, 1979). The participants with more elder sisters viewed their parents' attitudes as less caring, whereas those with more brothers, particularly younger brothers, viewed their parents' attitudes as less overprotective. However, the proportion of the variance of all the PBI scores explained by different types of siblings was very small.
Code of Federal Regulations, 2010 CFR
2010-04-01
... transaction occurred, then a deduction by the donor with respect to the gift or contribution shall not be disallowed under section 503(b) unless the donor (or any member of his family if the donor is an individual... defined in section 267(c)(4) and includes brothers and sisters, whether by whole or half blood, spouse...
The Birth and Development of Sociometry: The Work and Legacy of Jacob Moreno (1889-1974)
ERIC Educational Resources Information Center
Marineau, Rene F.
2007-01-01
This article profiles Jacob Levy Moreno, the founder of this journal. He was born in 1889 in Romania, but moved to Vienna with his parents when he was four years of age. By all accounts, Moreno as a child was brilliant, spontaneous, creative and, presaging his later successes, was fascinated by relationships, first with his brothers and sisters,…
ERIC Educational Resources Information Center
Gopman, Beth Alswanger
2009-01-01
Although study and research focus on the needs of children with mental and physical disabilities, this pilot study focuses on the siblings of children with a special need (SCSN), those brothers and sisters who face unique stresses in their own lives. The study explores the world of the nondisabled siblings, identifies some of the problems they…
Developing Support for Siblings of Young People with Disabilities
ERIC Educational Resources Information Center
Conway, Sally; Meyer, Donald
2008-01-01
In the USA and UK, at least one in ten children and young people have special health, developmental and mental health concerns. Most of these people have typically developing brothers and sisters. As the people who, over the course of their lifetimes together, will be most involved with their siblings with special needs, it is important that…
Sibling Voices: The Self-Reported Mental Health of Siblings of Children with a Disability
ERIC Educational Resources Information Center
Giallo, Rebecca; Gavidia-Payne, Susana; Minett, Belinda; Kapoor, Aparna
2012-01-01
Background: There is increasing interest in the experiences and well-being of siblings growing up with a brother or sister with a disability in Australia. However, research to date has primarily obtained parent reports of sibling adjustment and mental health. Therefore, the aim of the current study was threefold: (1) to report on the mental health…
ERIC Educational Resources Information Center
Brimner, Larry Dane
This book incorporates many photographs portraying the life of a migrant family in a camp near San Diego, California. Houses in the camp are built of salvaged plywood with plastic sheets as roofs. Twelve-year-old Juan and his two younger brothers sleep on an old mattress atop a plywood platform. Juan's mother, stepfather, and younger sister sleep…
20 CFR 725.201 - Who is entitled to benefits; contents of this subpart.
Code of Federal Regulations, 2014 CFR
2014-04-01
... parent, of a miner, who meet the conditions of entitlement set forth in § 725.222; or (5) The child of a... applicable to a miner, or a surviving spouse, child, parent, brother, or sister, and the events which...; or, (3) Where neither exists, the child of a deceased miner who meets the conditions of entitlement...
Saccharomyces cerevisiae CTF18 and CTF4 Are Required for Sister Chromatid Cohesion
Hanna, Joseph S.; Kroll, Evgueny S.; Lundblad, Victoria; Spencer, Forrest A.
2001-01-01
CTF4 and CTF18 are required for high-fidelity chromosome segregation. Both exhibit genetic and physical ties to replication fork constituents. We find that absence of either CTF4 or CTF18 causes sister chromatid cohesion failure and leads to a preanaphase accumulation of cells that depends on the spindle assembly checkpoint. The physical and genetic interactions between CTF4, CTF18, and core components of replication fork complexes observed in this study and others suggest that both gene products act in association with the replication fork to facilitate sister chromatid cohesion. We find that Ctf18p, an RFC1-like protein, directly interacts with Rfc2p, Rfc3p, Rfc4p, and Rfc5p. However, Ctf18p is not a component of biochemically purified proliferating cell nuclear antigen loading RF-C, suggesting the presence of a discrete complex containing Ctf18p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p. Recent identification and characterization of the budding yeast polymerase κ, encoded by TRF4, strongly supports a hypothesis that the DNA replication machinery is required for proper sister chromatid cohesion. Analogous to the polymerase switching role of the bacterial and human RF-C complexes, we propose that budding yeast RF-CCTF18 may be involved in a polymerase switch event that facilities sister chromatid cohesion. The requirement for CTF4 and CTF18 in robust cohesion identifies novel roles for replication accessory proteins in this process. PMID:11287619
The Wright Brothers and the Future of Bio-Inspired Flight: 1899 through to the Future
NASA Technical Reports Server (NTRS)
Bowers, Albion
2007-01-01
This viewgraph presentation reviews the experiments that the Wright Brothers conducted prior to their first powered flight in 1903 to developing the first practical aircraft in 1905. Many pictures of the gliders and other devices are used to illustrate the gradual development and experimentation that proceeded the first powered flight.
NASA Astrophysics Data System (ADS)
Bourdon, Estelle
2005-12-01
The phylogenetic affinities of the extinct pseudo-toothed birds have remained controversial. Some authors noted that they resemble both pelicans and allies (Pelecaniformes) and tube-nosed birds (Procellariiformes), but assigned them to a distinct taxon, the Odontopterygiformes. In most recent studies, the pseudo-toothed birds are referred to the family Pelagornithidae inside the Pelecaniformes. Here, I perform a cladistic analysis with five taxa of the pseudo-toothed birds including two undescribed new species from the Early Tertiary of Morocco. The present hypothesis strongly supports a sister group relationship of pseudo-toothed birds (Odontopterygiformes) and waterfowls (Anseriformes). The Odontoanserae (Odontopterygiformes plus Anseriformes) are the sister group of Neoaves. The placement of the landfowls (Galliformes) as the sister taxon of all other neognathous birds does not support the consensus view that the Galloanserae (Galliformes plus Anseriformes) are monophyletic.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-15
... Genetic and Environmental Risk Factors for Breast Cancer SUMMARY: In compliance with the requirement of... Sister Study: A Prospective Study of the Genetic and Environmental Risk Factors for Breast Cancer. Type... the development of breast cancer in a high-risk cohort of sisters of women who have had breast cancer...
Chitayat, D; Moore, L; Del Bigio, M R; MacGregor, D; Ben-Zeev, B; Hodgkinson, K; Deck, J; Stothers, T; Ritchie, S; Toi, A
1994-10-01
Brothers are reported with an apparently new constellation of manifestations including Dandy-Walker complex (DWC), migrational brain disorder, macrocephaly, and facial anomalies. The first brother presented at birth, the second was detected prenatally with DWC and the pregnancy terminated. Fetal brain histopathology showed DWC associated with brainstem dysgenesis. Inheritance is likely autosomal or X-linked recessive. An extensive review of the differential diagnosis of DWC is provided.
Infant welfare, philanthropy and entrepreneurship in Glasgow: Sister Laura's Infant Food Company.
Weaver, L T
2008-06-01
Laura Smith was sister-in-charge of the Children's Dispensary in Glasgow from 1897 to 1922. In 1911 she established Sister Laura's Infant Food Company to market a special milk formula of her own invention.The directors of the Dispensary were not amused. As the 'outdoor' department of the Royal Hospital for Sick Children (Yorkhill), the Dispensary was at the forefront of efforts to combat child ill health and malnutrition. This paper considers Laura Smith's initiative within the context of the health and care of infants of the time - high infant mortality, public and professional concerns for infant welfare, technological advances in food science, changing recommendations and practices of infant feeding and ambiguous relations between medicine and commerce.
The Younger Siblings of Teenage Mothers: A Follow-Up of Their Pregnancy Risk
East, Patricia L.; Jacobson, Leanne J.
2013-01-01
This study followed 243 younger brothers and younger sisters of parenting teens and nonparenting teens across a 1.5-year period. The average age of siblings was 13.6 years at Time 1 and 15 years at Time 2. Relative to other youths, the sisters of parenting teens exhibited a sharp increase in drug and alcohol use and partying behavior across time and had the highest pregnancy rate at Time 2 (15%). The siblings of parenting teens spent 10 hr a week caring for their sisters’ children, and, for girls, many hours of child care was associated with negative outcomes including permissive sexual behavior. Findings suggest that the younger sisters of parenting teens are at very high risk of early pregnancy and that this risk becomes increasingly pronounced across time. PMID:11269393
X-linked mental retardation syndrome: Three brothers with the Brooks-Wisniewski-Brown syndrome
DOE Office of Scientific and Technical Information (OSTI.GOV)
Morava, E.; Storcz, J.; Kosztolanyi, G.
1996-07-12
We report on 3 brothers with growth and mental retardation, bifrontal narrowness, short palpebral fissures, deeply set eyes with entropion, wide bulbous nose, small mouth, myopia, and spastic diplegia. The patients were born to normal and non-consanguineous parents. The similarity of our cases with those recently reported by Brooks et al. supports their suggestion that these patients are representative of a distinct entity. 8 refs., 3 figs., 1 tab.
Latt, S A; Stetten, G; Juergens, L A; Buchanan, G R; Gerald, P S
1975-10-01
Sister chromatid exchanges, which may reflect chromosome repair in response to certain types of DNA damage, provide a means of investigating the increased chromosome fragility characteristic of Fanconi's anemia. By a recently developed technique using 33258 Hoechst and 5-bromodeoxyuridine, it was observed that the baseline frequency of sister chromatid exchanges in phytohemagglutinin-stimulated lymphocytes from four males with Fanconi's anemia differed little from that of normal lymphocytes. However, addition of the bifunctional alkylating agent mitomycin C (0.01 or 0.03 mug/ml) to the Fanconi's anemia cells during culture induces less than half of the increase in exchanges found in identically treated normal lymphocytes. This reduced increment in exchanges in accompanied by a partial suppression of mitosis and a marked increase in chromatid breaks and rearrangements. Many of these events occur at sites of incomplete chromatid interchange. The increase in sister chromatid exchanges induced in Fanconi's anemia lymphocytes by the monofunctional alkylating agent ethylmethane sulfonate (0.25 mg/ml) was slightly less than that in normal cells. Lymphocytes from two sets of parents of the patients with Fanconi's anemia exhibited a normal response to alkylating agents, while dermal fibroblasts from two different patients with Fanconi's anemia reacted to mitomycin C with an increase in chromatid breaks, but a nearly normal increment of sister chromatid exchanges. The results suggest that chromosomal breaks and rearrangements in Fanconi's anemia lymphocytes may result from a defect in a form of repair of DNA damage.
In pursuit of sisterhood: adult siblings as a resource for combined individual and family therapy.
Kahn, M D; Bank, S
1981-03-01
Therapists traditionally view brothers and sisters as rivalrous and self-seeking. Under carefully arranged conditions, however, siblings can learn to cooperate with each other to resolve important conflicts in family relationships. This case documents a dramatic change in the relationship between a 29-year-old woman and her father, the outcome of a three-step therapeutic intervention in which sibling dynamics were selectively used by the psychotherapist. As part of her individual therapy, the therapist first aroused the woman's discontent with her status as the neglected "baby of the family." Next, a series of meetings were held with the woman and her three sisters that permitted resolution of their previous anger and misunderstandings, thus helping them to become a more cohesive group of sisters. The third step brought the sisters, now as allies both of the identified patient and of the therapist, into a constructive confrontation with the parents. This resulted in lasting personal change for the identified patient and improved relationships throughout the entire family.
Sister acts: coordinating DNA replication and cohesion establishment
Sherwood, Rebecca; Takahashi, Tatsuro S.; Jallepalli, Prasad V.
2010-01-01
The ring-shaped cohesin complex links sister chromatids and plays crucial roles in homologous recombination and mitotic chromosome segregation. In cycling cells, cohesin's ability to generate cohesive linkages is restricted to S phase and depends on loading and establishment factors that are intimately connected to DNA replication. Here we review how cohesin is regulated by the replication machinery, as well as recent evidence that cohesin itself influences how chromosomes are replicated. PMID:21159813
The Role of Digital Literacy Practices on Refugee Resettlement: The Case of Three Karen Brothers
ERIC Educational Resources Information Center
Gilhooly, Daniel; Lee, Eunbae
2014-01-01
This study explores the social and cultural uses of digital literacies by adolescent immigrants to cope with their new lives in the United States. This case study focuses on three adolescent ethnic Karen brothers. Two years of participant observations in their home and Karen community, accompanied by formal and informal interviews, served as the…
Isolated familial somatotropinomas: clinical features and analysis of the MEN1 gene.
De Menis, Ernesto; Prezant, Toni R
2002-01-01
Isolated familial somatotropinomas (IFS) rarely occurs in the absence of multiple endocrine neoplasia type I (MEN1) or the Carney complex. In the present study we report two Italian siblings affected by GH-secreting adenomas. There was no history of parental consanguinity. The sister presented at 18 years of age with secondary amenorrhea and acromegalic features and one of her two brothers presented with gigantism at the same age. Endocrinological investigations confirmed GH hypersecretion in both cases. Although a pituitary microadenoma was detected in both patients, transsphenoidal surgery was not successful. The sister received conventional radiotherapy and acromegaly is now considered controlled; the brother is being treated with octreotide LAR 30 mg monthly and the disease is considered clinically active. Patients, their parents and the unaffected brother underwent extensive evaluation, and no features of MEN1 or Carney complex were found. Analysis of polymorphic microsatellite markers from chromosome 11q13 (D11S599, D11S4945, D11S4939, D11S4938 and D11S987) showed that the acromegalic siblings had inherited different maternal chromosomes and shared the paternal chromosome. No pathogenic MEN1 sequence changes were detected by sequencing or dideoxy fingerprinting of the coding sequence (exons 2-10) and exon/intron junctions. Although mutations in the promoter, introns or untranslated regions of the MEN1 gene cannot be excluded, germline mutations within the coding region of this gene do not appear responsible for IFS in this family.
Yildirim, Ali; Ozer, Erdal; Bozkurt, Hasan; Ozsoy, Sait; Enginyurt, Ozgur; Evcuman, Durmus; Yilmaz, Riza; Kuyucu, Yunus Emre
2014-01-01
Background Incest is defined as any sexual activity between close blood relatives including step relatives and family members who are forbidden by law to marry. It is a problem that can be seen in all the social classes in developed and undeveloped societies. The World Health Organization classifies this problem as a silent health emergency. Father-daughter incest is reported to be the most common incest type followed by the other types like brother-sister, sister-sister and mother-son incest. Material/Methods Subjects for this study were recruited from a sample of incest cases referred to Forensic Medicine Department of Gaziosmanpasa University Medical Faculty Hospital between 2008 and 2012. Data involved social and demographic characteristics and clinical features of victims, perpetrators and the families. The ethical committee of the faculty of medicine approved the study. Results The study sample consisted of 43 incest cases (36 females and 7 males) with an age rage 4–40 years. Two third of the victims were under 18 years old. All perpetrators were males. Father – daughter incest (34.9%) was found to be most common incest type followed by brother – sister incest (14%). 75% of the perpetrators were family members and relatives with consanguinity while 25% of them were not consanguineous but faithful and intimate relatives to victims. Conclusions Increasing awareness about incest and its damaging effects is so important and clinicians should keep in mind sexual abuse or incest when examining the risky population. Multidisciplinary approach is necessary for determining short term or long term results and preventing the negative consequences of incest. PMID:24770724
BigBWA: approaching the Burrows-Wheeler aligner to Big Data technologies.
Abuín, José M; Pichel, Juan C; Pena, Tomás F; Amigo, Jorge
2015-12-15
BigBWA is a new tool that uses the Big Data technology Hadoop to boost the performance of the Burrows-Wheeler aligner (BWA). Important reductions in the execution times were observed when using this tool. In addition, BigBWA is fault tolerant and it does not require any modification of the original BWA source code. BigBWA is available at the project GitHub repository: https://github.com/citiususc/BigBWA. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
"Breaking up is hard to do": the formation and resolution of sister chromatid intertwines.
Baxter, Jonathan
2015-02-13
The absolute necessity to resolve every intertwine between the two strands of the DNA double helix provides a massive challenge to the cellular processes that duplicate and segregate chromosomes. Although the overwhelming majority of intertwines between the parental DNA strands are resolved during DNA replication, there are numerous chromosomal contexts where some intertwining is maintained into mitosis. These mitotic sister chromatid intertwines (SCIs) can be found as; short regions of unreplicated DNA, fully replicated and intertwined sister chromatids--commonly referred to as DNA catenation--and as sister chromatid linkages generated by homologous recombination-associated processes. Several overlapping mechanisms, including intra-chromosomal compaction, topoisomerase action and Holliday junction resolvases, ensure that all SCIs are removed before they can prevent normal chromosome segregation. Here, I discuss why some DNA intertwines persist into mitosis and review our current knowledge of the SCI resolution mechanisms that are employed in both prokaryotes and eukaryotes, including how deregulating SCI formation during DNA replication or disrupting the resolution processes may contribute to aneuploidy in cancer. Copyright © 2014 Elsevier Ltd. All rights reserved.
Jelenkovic, Aline; Silventoinen, Karri; Tynelius, Per; Helle, Samuli; Rasmussen, Finn
2014-08-01
In many mammal species with sexual dimorphism producing sons is energetically more demanding to the mother than producing daughters. Although some studies in humans have suggested that offspring born after a brother have a smaller birth weight and adult height when compared with those born after a sister, little is known about this intergenerational cost of producing sons. We aimed to study whether the sex of preceding sibling is associated with anthropometrics of the subsequent child at birth and in young adulthood. This population-based study was carried out on two data sets derived from the Swedish registers. Information on birth weight and length was obtained for 752,723 children of both sexes. Adult weight, height and muscle strength were available for 506,326 men. Multiple linear regression analyses showed that boys and girls born after a brother were, respectively, 18 and 9 g lighter and 0.08 and 0.03 cm (P < 0.001) shorter at birth than those born after a sister. Adjustment for gestational age decreased the magnitude of the associations [10 g and 0.04 cm (P < 0.001) in men and nonsignificant estimates in women], suggesting that part of the lower mean birth weight and length of individuals born after a brother was due to a shorter gestation. In young adulthood, men with a preceding brother showed 0.16 kg more in weight, 0.3% higher body mass index (P < 0.001) and a trend towards reduced height and muscle strength. Our results suggest that even though the sex of the previous child is associated with the anthropometrics of the subsequent child, the effect sizes are very small questioning whether this mechanism has adaptive value in contemporary humans. © 2014 Wiley Periodicals, Inc.
I'll Never Forget Mr. White: A Teacher's Legacy
ERIC Educational Resources Information Center
Waddell, Andy
2012-01-01
A man died last summer. At 78, he was neither old enough nor young enough for his passing to make news. His obituary was two paragraphs long. The "San Jose Mercury News" simply stated that Edward A. White was survived by "his brother Mike, his sister Mary and his many loving nieces and nephews." "As a passionate High School English Teacher" the…
Theoretical Dimensions of Small Unit Resilience
2010-12-01
ending process and everyday and every experience offers a new education. Keep learning and keep moving forward. To my brother and sister Soldiers...strategies and coping mechanisms. 13 Unit Leadership and Coping Willingness to Seek Care Reducing Barriers to Care Family and Marital Support...identifies the following 10 combat skills: Buddies (Cohesion) Accountability Targeted Aggression 14 15 Tactical Awareness Lethally Armed Emotional
2015-03-01
selected by matching on sex , race, and approximate physical appearance. Thus, there were two honest non-cheaters and two lying cheaters, all of whom...immediate family member (brother, sister, mom , dad), peer/friend, teacher/caregiver, senior in rank (but no command relationship), and other. Relationship...Please tell us about yourself (circle the correct answer or fill in the blank): Sex : Male Female Age
The State of the World's Children, 2013: Children with Disabilities
ERIC Educational Resources Information Center
UNICEF, 2013
2013-01-01
Reports such as this typically begin with a statistic designed to highlight a problem. The girls and boys to whom this edition of "The State of the World's Children" is dedicated are not problems. Rather, each is a sister, brother or friend who has a favourite dish, song or game; a daughter or son with dreams and the desire to fulfil…
Haimi, Motti; Gershoni-Baruch, Ruth
2005-10-15
We describe a brother and sister with retinitis pigmentosa (RP), growth failure, long eyelashes, and sparse hair. They were born to young healthy consanguineous parents and presented at birth with IUGR. Evolving pigmentary retinopathy was diagnosed at the age of 5 years. A similar condition (Oliver-McFarlane) syndrome was reported previously. Our two sibs confirm the existence of this autosomal recessive syndrome.
Mroske, Cameron; Rasmussen, Kristen; Shinde, Deepali N; Huether, Robert; Powis, Zoe; Lu, Hsiao-Mei; Baxter, Ruth M; McPherson, Elizabeth; Tang, Sha
2015-11-05
In humans, Mammalian Target of Rapamycin (MTOR) encodes a 300 kDa serine/ threonine protein kinase that is ubiquitously expressed, particularly at high levels in brain. MTOR functions as an integrator of multiple cellular processes, and in so doing either directly or indirectly regulates the phosphorylation of at least 800 proteins. While somatic MTOR mutations have been recognized in tumors for many years, and more recently in hemimegalencephaly, germline MTOR mutations have rarely been described. We report the successful application of family-trio Diagnostic Exome Sequencing (DES) to identify the underlying molecular etiology in two brothers with multiple neurological and developmental lesions, and for whom previous testing was non-diagnostic. The affected brothers, who were 6 and 23 years of age at the time of DES, presented symptoms including but not limited to mild Autism Spectrum Disorder (ASD), megalencephaly, gross motor skill delay, cryptorchidism and bilateral iris coloboma. Importantly, we determined that each affected brother harbored the MTOR missense alteration p.E1799K (c.5395G>A). This exact variant has been previously identified in multiple independent human somatic cancer samples and has been shown to result in increased MTOR activation. Further, recent independent reports describe two unrelated families in whom p.E1799K co-segregated with megalencephaly and intellectual disability (ID); in both cases, p.E1799K was shown to have originated due to germline mosaicism. In the case of the family reported herein, the absence of p.E1799K in genomic DNA extracted from the blood of either parent suggests that this alteration most likely arose due to gonadal mosaicism. Further, the p.E1799K variant exerts its effect by a gain-of-function (GOF), autosomal dominant mechanism. Herein, we describe the use of DES to uncover an activating MTOR missense alteration of gonadal mosaic origin that is likely to be the causative mutation in two brothers who present
ERIC Educational Resources Information Center
Olneck, Michael R.; Bills, David B.
1979-01-01
Birth order effects in brothers were found to derive from difference in family size. Effects for family size were found even with socioeconomic background controlled. Nor were family size effects explained by parental ability. The importance of unmeasured preferences or economic resources that vary across families was suggested. (Author/RD)
ERIC Educational Resources Information Center
Sanacore, Joseph
2017-01-01
Barack Obama's "My Brother's Keeper" is designed to narrow persistent gaps that boys and young men of color confront often and to help all young people achieve their potential in college and career. An important part of this initiative is comprehensive mentoring that supports students in schools and in communities. Because…
ERIC Educational Resources Information Center
Pompeo, Michelle N.
2009-01-01
This study is a retrospective look at adult female siblings' perspectives of their childhoods and present identities based on having a brother with a disability. This paper focuses on siblings' experiences within educational and public domains, and how such experiences have shaped their personalities and career choices. Qualitative findings were…
Bartter syndrome in two sisters with a novel mutation of the CLCNKB gene, one with deafness.
Robitaille, Pierre; Merouani, Aicha; He, Ning; Pei, York
2011-09-01
This article describes two sisters with type III Bartter syndrome (BS) due to a novel missense variant of the CLCNKB gene. The phenotypic expression of the disease was very different in these two siblings. In one sister, the disease followed a very severe course, especially in the neonatal period and as a toddler. Both the classic symptoms and the biochemical features of the syndrome were striking. In addition, she presented with sensorineural deafness, a complication yet unreported in this subtype of BS In contrast, the least affected sister was symptom free and the biochemical features of the disease although present remained discrete throughout the prolonged follow-up. It is suggested that such a difference in the phenotypic expression of the disease is possibly secondary to the modifier effect of a gene and/or results from environmental factor(s).
Accuracy and reliability of self-reported weight and height in the Sister Study
Lin, Cynthia J; DeRoo, Lisa A; Jacobs, Sara R; Sandler, Dale P
2012-01-01
Objective To assess accuracy and reliability of self-reported weight and height and identify factors associated with reporting accuracy. Design Analysis of self-reported and measured weight and height from participants in the Sister Study (2003–2009), a nationwide cohort of 50,884 women aged 35–74 in the United States with a sister with breast cancer. Setting Weight and height were reported via computer-assisted telephone interview (CATI) and self-administered questionnaires, and measured by examiners. Subjects Early enrollees in the Sister Study. There were 18,639 women available for the accuracy analyses and 13,316 for the reliability analyses. Results Using weighted kappa statistics, comparisons were made between CATI responses and examiner measures to assess accuracy and CATI and questionnaire responses to assess reliability. Polytomous logistic regression evaluated factors associated with over- or under-reporting. Compared to measured values, agreement was 96% for reported height (±1 inch; weighted kappa 0.84) and 67% for weight (±3 pounds; weighted kappa 0.92). Obese women [body mass index (BMI) ≥30 kg/m2)] were more likely than normal weight women to under-report weight by ≥5% and underweight women (BMI <18.5 kg/m2) were more likely to over-report. Among normal and overweight women (18.5 kgm2≤ BMI <30 kgm2), weight cycling and lifetime weight difference ≥50 pounds were associated with over-reporting. Conclusions U.S. women in the Sister Study were reasonably reliable and accurate in reporting weight and height. Women with normal-range BMI reported most accurately. Overweight and obese women and those with weight fluctuations were less accurate, but even among obese women, few under-reported their weight by >10%. PMID:22152926
Sibship Size and Gendered Resource Dilution in Different Societal Contexts
Kalmijn, Matthijs
2016-01-01
Resource dilution theory hypothesizes that children’s educational attainment suffers from being raised with many siblings, as the parental resources have to be shared with more children. Based on economic and cultural theories, we hypothesize that resource dilution is gendered: especially a larger number of brothers is harmful to a person’s educational attainment. Using the Survey of Health, Ageing and Retirement in Europe, covering 18 European countries, we show that the number of brothers is more negatively related with the odds of obtaining a college degree than the number of sisters. This holds particularly for women. However, this pattern is weaker in countries that are known to have a more gender-egalitarian climate. PMID:27560371
Rodriguez, Fátima; Naderi, Sahar; Wang, Yun; Johnson, Caitlin E; Foody, JoAnne M
2013-04-01
Hispanics are the fastest growing segment of the U.S. population and have a higher prevalence of cardiometabolic risk factors as compared with non-Hispanic whites. Further data suggests that Hispanics have undiagnosed complications of metabolic syndrome, namely diabetes mellitus, at an earlier age. We sought to better understand the epidemiology of metabolic syndrome in Hispanic women using data from a large, community-based health screening program. Using data from the Sister to Sister: The Women's Heart Health Foundation community health fairs from 2008 to 2009 held in 17 U.S. cities, we sought to characterize how cardiometabolic risk profiles vary across age for women by race and ethnicity. Metabolic syndrome was defined using the updated National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guidelines, which included three or more of the following: Waist circumference ≥35 inches, triglycerides ≥150 mg/dL, high-density lipoprotein (HDL) <50 mg/dL, systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥85 mmHg, or a fasting glucose ≥100 mg/dL. A total of 6843 community women were included in the analyses. Metabolic syndrome had a prevalence of 35%. The risk-adjusted odds ratio for metabolic syndrome in Hispanic women versus white women was 1.7 (95% confidence interval, 1.4, 2.0). Dyslipidemia was the strongest predictor of metabolic syndrome among Hispanic women. This disparity appeared most pronounced for younger women. Additional predictors of metabolic syndrome included black race, increasing age, and smoking. In a large, nationally representative sample of women, we found that metabolic syndrome was highly prevalent among young Hispanic women. Efforts specifically targeted to identifying these high-risk women are necessary to prevent the cardiovascular morbidity and mortality associated with metabolic syndrome.
Benchmarking Big Data Systems and the BigData Top100 List.
Baru, Chaitanya; Bhandarkar, Milind; Nambiar, Raghunath; Poess, Meikel; Rabl, Tilmann
2013-03-01
"Big data" has become a major force of innovation across enterprises of all sizes. New platforms with increasingly more features for managing big datasets are being announced almost on a weekly basis. Yet, there is currently a lack of any means of comparability among such platforms. While the performance of traditional database systems is well understood and measured by long-established institutions such as the Transaction Processing Performance Council (TCP), there is neither a clear definition of the performance of big data systems nor a generally agreed upon metric for comparing these systems. In this article, we describe a community-based effort for defining a big data benchmark. Over the past year, a Big Data Benchmarking Community has become established in order to fill this void. The effort focuses on defining an end-to-end application-layer benchmark for measuring the performance of big data applications, with the ability to easily adapt the benchmark specification to evolving challenges in the big data space. This article describes the efforts that have been undertaken thus far toward the definition of a BigData Top100 List. While highlighting the major technical as well as organizational challenges, through this article, we also solicit community input into this process.
EVIDENCE FOR THE CHROMOSOMAL REPLICONS AS UNITS OF SISTER CHROMATID EXCHANGES
Current hypotheses of sister chromatid exchange (SCE) formation postulate that sites of SCE induction are associated with active replicons or replicon clusters. We have applied the FCC-SCD technique to in vivo studies of mouse bone marrow cells that have been treated with cycloph...
Big data, big knowledge: big data for personalized healthcare.
Viceconti, Marco; Hunter, Peter; Hose, Rod
2015-07-01
The idea that the purely phenomenological knowledge that we can extract by analyzing large amounts of data can be useful in healthcare seems to contradict the desire of VPH researchers to build detailed mechanistic models for individual patients. But in practice no model is ever entirely phenomenological or entirely mechanistic. We propose in this position paper that big data analytics can be successfully combined with VPH technologies to produce robust and effective in silico medicine solutions. In order to do this, big data technologies must be further developed to cope with some specific requirements that emerge from this application. Such requirements are: working with sensitive data; analytics of complex and heterogeneous data spaces, including nontextual information; distributed data management under security and performance constraints; specialized analytics to integrate bioinformatics and systems biology information with clinical observations at tissue, organ and organisms scales; and specialized analytics to define the "physiological envelope" during the daily life of each patient. These domain-specific requirements suggest a need for targeted funding, in which big data technologies for in silico medicine becomes the research priority.
Narcolepsy with Cataplexy Mimicry: The Strange Case of Two Sisters
Pizza, Fabio; Vandi, Stefano; Poli, Francesca; Moghadam, Keivan Kaveh; Franceschini, Christian; Bellucci, Claudia; Cipolli, Carlo; Ingravallo, Francesca; Natalini, Giuliana; Mignot, Emmanuel; Plazzi, Giuseppe
2013-01-01
We report on two sisters, 17 and 12 years of age, with clinical features suggesting narcolepsy with cataplexy (NC): daytime sleepiness, spontaneous and emotionally triggered sudden falls to the ground, and overweight/obesity. MSLT showed borderline sleep latency, with 1 and 0 sleep onset REM periods. HLA typing disclosed the DQB1*0602 allele. Video-polygraphy of the spells ruled out NC diagnosis by demonstrating their easy elicitation by suggestion, with wake EEG, electromyo-graphic persistence of muscle tone, and stable presence of tendon reflexes (i.e., pseudo-cataplexy), together with normal cerebrospinal hypocretin-1 levels. Our cases emphasize the need of a clear depiction of cataplexy pattern at the different ages, the usefulness of examining ictal neurophysiology, and collecting all available disease markers in ambiguous cases. Citation: Pizza F; Vandi S; Poli F; Moghadam KK; Fran-ceschini C; Bellucci C; Cipolli C; Ingravallo F; Natalini G; Mignot E; Plazzi G. Narcolepsy with cataplexy mimicry: the strange case of two sisters. J Clin Sleep Med 2013;9(6):611-612. PMID:23772196
Flow behavior in the Wright Brothers Facility
NASA Technical Reports Server (NTRS)
Genn, S.
1984-01-01
It has become increasingly apparent that a reexamination of the flow characteristics in the low speed Wright Brothers Facility (WBF) is of some importance in view of recent improvements in the precision of the data acquisition system. In particular, the existence of local regions of separation, if any, in back portions of the circuit, and possible related unsteadiness, are of interest. Observations from that initial experiment did indicate some unsteady air flow problems in the cross leg, and thereafter the test region (Section A) was calibrated quantitatively. The intent was to learn something about the effect of upstream intermittent behavior flow on the test section flow, as well as to provide an extensive calibration as a standard for the effects induced by future alteration of the tunnel. Distributions of total pressure coefficients were measured first at one cross-section plane of the test section, namely the model station. Data were obtained for several tunnel speeds. The reduced data yielded an unexpected distribution involving larger pressures along the inside wall.
Choudoir, Mallory J; Buckley, Daniel H
2018-06-07
The latitudinal diversity gradient is a pattern of biogeography observed broadly in plants and animals but largely undocumented in terrestrial microbial systems. Although patterns of microbial biogeography across broad taxonomic scales have been described in a range of contexts, the mechanisms that generate biogeographic patterns between closely related taxa remain incompletely characterized. Adaptive processes are a major driver of microbial biogeography, but there is less understanding of how microbial biogeography and diversification are shaped by dispersal limitation and drift. We recently described a latitudinal diversity gradient of species richness and intraspecific genetic diversity in Streptomyces by using a geographically explicit culture collection. Within this geographically explicit culture collection, we have identified Streptomyces sister-taxa whose geographic distribution is delimited by latitude. These sister-taxa differ in geographic distribution, genomic diversity, and ecological traits despite having nearly identical SSU rRNA gene sequences. Comparative genomic analysis reveals genomic differentiation of these sister-taxa consistent with restricted gene flow across latitude. Furthermore, we show phylogenetic conservatism of thermal traits between the sister-taxa suggesting that thermal trait adaptation limits dispersal and gene flow across climate regimes as defined by latitude. Such phylogenetic conservatism of thermal traits is commonly associated with latitudinal diversity gradients for plants and animals. These data provide further support for the hypothesis that the Streptomyces latitudinal diversity gradient was formed as a result of historical demographic processes defined by dispersal limitation and driven by paleoclimate dynamics.
ERIC Educational Resources Information Center
Tebb, Kathleen P.
This study evaluated Sister Friend, a mentoring program in Yolo County, California, serving low-income adolescent mothers and their infants. The primary objective was to determine if participating in the Sister Friend program improved the adolescent mother's parenting class attendance, the home environment, parenting behavior, and child…