Influence of hypergravity on fish inner ear otoliths: II. Incorporation of calcium and kinetotic behaviour.

PubMed

Beier, M; Anken, R H; Rahmann, H

2002-01-01

Larval siblings of cichlid fish (Oreochromis mossambicus) were subjected to hypergravity (hg; 3 g, 14 days) during development. Following the transfer to 1 g (i.e., stopping the centrifuge) they were separated into normally and kinetotically swimming individuals (the latter performed spinning movements). During hg, the animals were maintained in aquarium water containing alizarin-complexone (AC), a fluorescent calcium tracer. Densitometric measurements of AC uptake into inner ear otoliths (optical density of AC/micrometers2) revealed that the kinetotic individuals had incorporated significantly more AC/calcium than the normally behaving fish. Since the amount of otolithic calcium can be taken as an approximation for otolith weight, the present results indicate that the otoliths of kinetotically swimming samples were heavier than those of the normally behaving larvae, thus exhibiting a higher absolute weight asymmetry of the otoliths between the right vs. the left side of the body. This supports an earlier concept according to which otolith (or statolith) asymmetry is the cause for kinetoses such as human static space sickness. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Chromosome aberrations in human lymphocytes induced by 250 MeV protons: effects of dose, dose rate and shielding.

PubMed

George, K; Willingham, V; Wu, H; Gridley, D; Nelson, G; Cucinotta, F A

2002-01-01

Although the space radiation environment consists predominantly of energetic protons, astronauts inside a spacecraft are chronically exposed to both primary particles as well as secondary particles that are generated when the primary particles penetrate the spacecraft shielding. Secondary neutrons and secondary charged particles can have an LET value that is greater than the primary protons and, therefore, produce a higher relative biological effectiveness (RBE). Using the accelerator facility at Loma Linda University, we exposed human lymphocytes in vitro to 250 MeV protons with doses ranging from 0 to 60 cGy at three different dose rates: a low dose rate of 7.5 cGy/h, an intermediate dose rate of 30 cGy/h and a high dose rate of 70 cGy/min. The effect of 15 g/cm2 aluminum shielding on the induction of chromosome aberrations was investigated for each dose rate. After exposure, lymphocytes were incubated in growth medium containing phytohemagglutinin (PHA) and chromosome spreads were collected using a chemical-induced premature chromosome condensation (PCC) technique. Aberrations were analyzed using the fluorescence in situ hybridization (FISH) technique with three different colored chromosome-painting probes. The frequency of reciprocal and complex-type chromosome exchanges were compared in shielded and unshielded samples. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Chromosome aberrations in human lymphocytes induced by 250 MeV protons: effects of dose, dose rate and shielding

NASA Technical Reports Server (NTRS)

George, K.; Willingham, V.; Wu, H.; Gridley, D.; Nelson, G.; Cucinotta, F. A.

2002-01-01

Although the space radiation environment consists predominantly of energetic protons, astronauts inside a spacecraft are chronically exposed to both primary particles as well as secondary particles that are generated when the primary particles penetrate the spacecraft shielding. Secondary neutrons and secondary charged particles can have an LET value that is greater than the primary protons and, therefore, produce a higher relative biological effectiveness (RBE). Using the accelerator facility at Loma Linda University, we exposed human lymphocytes in vitro to 250 MeV protons with doses ranging from 0 to 60 cGy at three different dose rates: a low dose rate of 7.5 cGy/h, an intermediate dose rate of 30 cGy/h and a high dose rate of 70 cGy/min. The effect of 15 g/cm2 aluminum shielding on the induction of chromosome aberrations was investigated for each dose rate. After exposure, lymphocytes were incubated in growth medium containing phytohemagglutinin (PHA) and chromosome spreads were collected using a chemical-induced premature chromosome condensation (PCC) technique. Aberrations were analyzed using the fluorescence in situ hybridization (FISH) technique with three different colored chromosome-painting probes. The frequency of reciprocal and complex-type chromosome exchanges were compared in shielded and unshielded samples. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Reports and recommendations from COSPAR Planetary Exploration Committee (PEX) & International Lunar Exploration Working Group (ILEWG)

NASA Astrophysics Data System (ADS)

Ehrenfreund, Pascale; Foing, Bernard

2014-05-01

In response to the growing importance of space exploration, the objectives of the COSPAR Panel on Exploration (PEX) are to provide high quality, independent science input to support the development of a global space exploration program while working to safeguard the scientific assets of solar system bodies. PEX engages with COSPAR Commissions and Panels, science foundations, IAA, IAF, UN bodies, and IISL to support in particular national and international space exploration working groups and the new era of planetary exploration. COSPAR's input, as gathered by PEX, is intended to express the consensus view of the international scientific community and should ultimately provide a series of guidelines to support future space exploration activities and cooperative efforts, leading to outstanding scientific discoveries, opportunities for innovation, strategic partnerships, technology progression, and inspiration for people of all ages and cultures worldwide. We shall focus on the lunar exploration aspects, where the COSPAR PEX is building on previous COSPAR, ILEWG and community conferences. An updated COSPAR PEX report is published and available online (Ehrenfreund P. et al, COSPAR planetary exploration panel report, http://www.gwu.edu/~spi/assets/COSPAR_PEX2012.pdf). We celebrate 20 years after the 1st International Conference on Exploration and Utilisation of the Moon at Beatenberg in June 1994. The International Lunar Exploration Working Group (ILEWG) was established the year after in April 1995 at an EGS meeting in Hamburg, Germany. As established in its charter, this working group reports to COSPAR and is charged with developing an international strategy for the exploration of the Moon (http://sci.esa.int/ilewg/ ). It discusses coordination between missions, and a road map for future international lunar exploration and utilisation. It fosters information exchange or potential and real future lunar robotic and human missions, as well as for new scientific and exploration information about the Moon. We present the GLUC/ICEUM11 declaration (with emphasis on Science and exploration; Technologies and resources, Infrastructures and human aspects; Moon, Space, Society and Young Explorers) (http://sci.esa.int/iceum11). We give a report on ongoing relevant ILEWG community activities. We discuss how lunar missions SMART-1, Kaguya, Chang'E1&2, Chandrayaan-1, LCROSS, LRO, GRAIL, LADEE, Chang'E3 and upcoming missions contribute to lunar exploration objectives & roadmap.

Gravitational unloading effects on muscle fiber size, phenotype and myonuclear number

NASA Technical Reports Server (NTRS)

Ohira, Y.; Yoshinaga, T.; Nomura, T.; Kawano, F.; Ishihara, A.; Nonaka, I.; Roy, R. R.; Edgerton, V. R.

2002-01-01

The effects of gravitational unloading with or without intact neural activity and/or tension development on myosin heavy chain (MHC) composition, cross-sectional area (CSA), number of myonuclei, and myonuclear domain (cytoplasmic volume per myonucleus ratio) in single fibers of both slow and fast muscles of rat hindlimbs are reviewed briefly. The atrophic response to unloading is generally graded as follows: slow extensors > fast extensors > fast flexors. Reduction of CSA is usually greater in the most predominant fiber type of that muscle. The percentage of fibers expressing fast MHC isoforms increases in unloaded slow but not fast muscles. Myonuclear number per mm of fiber length and myonuclear domain is decreased in the fibers of the unloaded predominantly slow soleus muscle, but not in the predominantly fast plantaris. Decreases in myonuclear number and domain, however, are observed in plantaris fibers when tenotomy, denervation, or both are combined with hindlimb unloading. All of these results are consistent with the view that a major factor for fiber atrophy is an inhibition or reduction of loading of the hindlimbs. These data also indicate that predominantly slow muscles are more responsive to unloading than predominantly fast muscles. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Nuclear model calculations and their role in space radiation research

NASA Technical Reports Server (NTRS)

Townsend, L. W.; Cucinotta, F. A.; Heilbronn, L. H.

2002-01-01

Proper assessments of spacecraft shielding requirements and concomitant estimates of risk to spacecraft crews from energetic space radiation requires accurate, quantitative methods of characterizing the compositional changes in these radiation fields as they pass through thick absorbers. These quantitative methods are also needed for characterizing accelerator beams used in space radiobiology studies. Because of the impracticality/impossibility of measuring these altered radiation fields inside critical internal body organs of biological test specimens and humans, computational methods rather than direct measurements must be used. Since composition changes in the fields arise from nuclear interaction processes (elastic, inelastic and breakup), knowledge of the appropriate cross sections and spectra must be available. Experiments alone cannot provide the necessary cross section and secondary particle (neutron and charged particle) spectral data because of the large number of nuclear species and wide range of energies involved in space radiation research. Hence, nuclear models are needed. In this paper current methods of predicting total and absorption cross sections and secondary particle (neutrons and ions) yields and spectra for space radiation protection analyses are reviewed. Model shortcomings are discussed and future needs presented. c2002 COSPAR. Published by Elsevier Science Ltd. All right reserved.

Overview of the 2008 COSPAR Planetary Protection Policy Workshop

NASA Astrophysics Data System (ADS)

Rummel, John

In January 2008 the COSPAR Panel on Planetary Protection held a Policy Workshop in Montŕal, Canada to consider a number of recommendations that had been suggested at prior e Panel business meetings for updating and clarifying the COSPAR Planetary Protection Policy that had been adopted at the World Space Congress in 2002. One particular element of the Policy that was due for clarification was the definition of "Special Regions" on Mars, which was discussed by the Panel at a Special Regions Colloquium in Rome in September 2008, and which was recommended for updating by both the US National Research Council's Committee on Preventing the Forward Contamination of Mars and by a Special Regions Science Analysis Group organized by NASA under its Mars Exploration Program Analysis Group in 2006. In other business, the Workshop also discussed and adopted wording to reflect the planetary protection considerations associated with future human missions to Mars (subsequent to several NASA and ESA workshops defining those), and addressed the planetary protection categorizations of both Venus and the Earth's Moon. The Workshop also defined a plan to move forward on the categorization of Outer Planet Satellites (to be done in conjunction with SC's B and F), and revised certain portions of the wording of the 1983 version of the COSPAR policy statement, emphasized full participation by all national members in planetary protection decisions and the need to study the ethical considerations of space exploration, and provided for a traceable version of the policy to be assembled and maintained by the Panel. This talk will review the Montŕal Workshop, and use its themes to introduce the remaining speakers in the session. e

Implementing planetary protection requirements for sample return missions.

PubMed

Rummel, J D

2000-01-01

NASA is committed to exploring space while avoiding the biological contamination of other solar system bodies and protecting the Earth against potential harm from materials returned from space. NASA's planetary protection program evaluates missions (with external advice from the US National Research Council and others) and imposes particular constraints on individual missions to achieve these objectives. In 1997 the National Research Council's Space Studies Board published the report, Mars Sample Return: Issues and Recommendations, which reported advice to NASA on Mars sample return missions, complementing their 1992 report, The Biological Contamination of Mars Issues and Recommendations. Meanwhile, NASA has requested a new Space Studies Board study to address sample returns from bodies other than Mars. This study recognizes the variety of worlds that have been opened up to NASA and its partners by small, relatively inexpensive, missions of the Discovery class, as well as the reshaping of our ideas about life in the solar system that have been occasioned by the Galileo spacecraft's discovery that an ocean under the ice on Jupiter's moon Europa might, indeed, exist. This paper will report on NASA's planned implementation of planetary protection provisions based on these recent National Research Council recommendations, and will suggest measures for incorporation in the planetary protection policy of COSPAR. c2001 COSPAR Published by Elsevier Science Ltd. All rights reserved.

The features of radiation dose variations onboard ISS and Mir space station: comparative study.

PubMed

Tverskaya, L V; Panasyuk, M I; Reizman, S Ya; Sosnovets, E N; Teltsov, M V; Tsetlin, V V

2004-01-01

The dynamics of the ISS-measured radiation dose variations since August 2000 is studied. Use is made of the data obtained with the R-16 instrument, which consists of two ionization chambers behind different shielding thicknesses. The doses recorded during solar energetic particle (SEP) events are compared with the data obtained also by R-16 on Mir space station. The SEP events in the solar maximum of the current cycle make a much smaller contribution to the radiation dose compared with the October 1989 event recorded on Mir space station. In the latter event, the proton intensity was peaking during a strong magnetic storm. The storm-time effect of solar proton geomagnetic cutoff decreases on dose variations is estimated. The dose variations on Mir space stations due to formation of a new radiation belt of high-energy protons and electrons during a sudden commencement of March 24, 1991 storm are also studied. It was for the first time throughout the ISS and Mir dose measurement period that the counting rates recorded by both R-16 channels on ISS in 2001-2002 were nearly the same during some time intervals. This effect may arise from the decreases of relativistic electron fluxes in the outer radiation belt. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

An alternative approach to solar system exploration providing safety of human mission to Mars.

PubMed

Gitelson, J I; Bartsev, S I; Mezhevikin, V V; Okhonin, V A

2003-01-01

For systematic human Mars exploration, meeting crew safety requirements, it seems perspective to assemble into a spacecraft: an electrical rocket, a well-shielded long-term life support system, and a manipulator-robots operating in combined "presence effect" and "master-slave" mode. The electrical spacecraft would carry humans to the orbit of Mars, providing short distance (and low signal time delay) between operator and robot-manipulators, which are landed on the surface of the planet. Long-term hybrid biological and physical/chemical LSS could provide environment supporting human health and well being. Robot-manipulators operating in "presence effect" and "master-slave" mode exclude necessity of human landing on Martian surface decreasing the level of risk for crew. Since crewmen would not have direct contact with the Martian environment then the problem of mutual biological protection is essentially reduced. Lightweight robot-manipulators, without heavy life support systems and without the necessity of returning to the mother vessel, could be sent as scouts to different places on the planet surface, scanning the most interesting for exobiological research site. Some approximate estimations of electric spacecraft, long-term hybrid LSS, radiation protection and mission parameters are conducted and discussed. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Solar particle event organ doses and dose equivalents for interplanetary crews: variations due to body size

NASA Technical Reports Server (NTRS)

Zapp, E. N.; Townsend, L. W.; Cucinotta, F. A.

2002-01-01

Proper assessments of spacecraft shielding requirements and concomitant estimates of risk to critical body organs of spacecraft crews from energetic space radiation require accurate, quantitative methods of characterizing the compositional changes in these radiation fields as they pass through the spacecraft and overlying tissue. When estimating astronaut radiation organ doses and dose equivalents it is customary to use the Computerized Anatomical Man (CAM) model of human geometry to account for body self-shielding. Usually, the distribution for the 50th percentile man (175 cm height; 70 kg mass) is used. Most male members of the U.S. astronaut corps are taller and nearly all have heights that deviate from the 175 cm mean. In this work, estimates of critical organ doses and dose equivalents for interplanetary crews exposed to an event similar to the October 1989 solar particle event are presented for male body sizes that vary from the 5th to the 95th percentiles. Overall the results suggest that calculations of organ dose and dose equivalent may vary by as much as approximately 15% as body size is varied from the 5th to the 95th percentile in the population used to derive the CAM model data. c2002 Published by Elsevier Science Ltd on behalf of COSPAR.

Probability of cell hits in selected organs and tissues by high-LET particles at the ISS orbit

NASA Technical Reports Server (NTRS)

Yasuda, H.; Komiyama, T.; Fujitaka, K.; Badhwar, G. D. (Principal Investigator)

2002-01-01

The fluence of high-LET particles (HLP) with LET infinity H2O greater than 15 keV micrometers-1 in selected organs and tissues were measured with plastic nuclear track detectors using a life-size human phantom on the 9th Shuttle-Mir Mission (STS-91). The planar-track fluence of HLP during the 9.8-day mission ranged from 1.9 x 10(3) n cm-2 (bladder) to 5.1 x 10(3) n cm-2 (brain) by a factor of 2.7. Based on these data, a probability of HLP hits to a matured cell of each organ or tissue was roughly estimated for a 90-day ISS mission. In the calculation, all cells were assumed to be spheres with a geometric cross-sectional area of 500 micrometers2 and the cell-hit frequency from isotropic space radiation can be described by the Poisson-distribution function. As results, the probability of one or more than 1 hit to a single cell by HLP for 90 days ranged from 17% to 38%; that of two or more than 2 hits was estimated to be 1.3-8.2%. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Engineering concepts for inflatable Mars surface greenhouses

NASA Technical Reports Server (NTRS)

Hublitz, I.; Henninger, D. L.; Drake, B. G.; Eckart, P.

2004-01-01

A major challenge of designing a bioregenerative life support system for Mars is the reduction of the mass, volume, power, thermal and crew-time requirements. Structural mass of the greenhouse could be saved by operating the greenhouse at low atmospheric pressure. This paper investigates the feasibility of this concept. The method of equivalent system mass is used to compare greenhouses operated at high atmospheric pressure to greenhouses operated at low pressure for three different lighting methods: natural, artificial and hybrid lighting. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Engineering concepts for inflatable Mars surface greenhouses.

PubMed

Hublitz, I; Henninger, D L; Drake, B G; Eckart, P

2004-01-01

A major challenge of designing a bioregenerative life support system for Mars is the reduction of the mass, volume, power, thermal and crew-time requirements. Structural mass of the greenhouse could be saved by operating the greenhouse at low atmospheric pressure. This paper investigates the feasibility of this concept. The method of equivalent system mass is used to compare greenhouses operated at high atmospheric pressure to greenhouses operated at low pressure for three different lighting methods: natural, artificial and hybrid lighting. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

The Mini-Earth facility and present status of habitation experiment program.

PubMed

Nitta, Keiji

2005-01-01

The history of construction of the CEEF (the Mini-Earth), the configuration and scale of the CEEF are initially described. The effective usable areas in plant cultivation and animal holding and habitation modules and the accommodation equipment installed in each module are also explained. Mechanisms of the material circulation systems belonging to each module and subsystems in each material circulation system are introduced. Finally the results of pre-habitation experiments conducted until the year 2004 for clarifying the requirements in order to promote final closed habitation experiments are shown. c2005 Published by Elsevier Ltd on behalf of COSPAR.

Considerations of design for life support systems.

PubMed

Ashida, Akira

2003-01-01

During the design phase for construction of artificial ecosystems, the following considerations are important. (1) Influences on living things in the ecosystem, such as lifestyles and physiological functions caused by stresses due to environmental changes. The long stay in the artificial ecosystem has a possibility to lead to evolutional change in the living things. (2) The system operation method in trouble, which relates to maintainability. (3) The system metamorphosis according to new technologies. (4) Route minimization of material flow that leads to an optimum system layout. c2003 Published by Elsevier Science Ltd on behalf of COSPAR.

Private Observatories in South Africa

NASA Astrophysics Data System (ADS)

Rijsdijk, C.

2016-12-01

Descriptions of private observatories in South Africa, written by their owners. Positions, equipment descriptions and observing programmes are given. Included are: Klein Karoo Observatory (B. Monard), Cederberg Observatory (various), Centurion Planetary and Lunar Observatory (C. Foster), Le Marischel Observatory (L. Ferreira), Sterkastaaing Observatory (M. Streicher), Henley on Klip (B. Fraser), Archer Observatory (B. Dumas), Overbeek Observatory (A. Overbeek), Overberg Observatory (A. van Staden), St Cyprian's School Observatory, Fisherhaven Small Telescope Observatory (J. Retief), COSPAR 0433 (G. Roberts), COSPAR 0434 (I. Roberts), Weltevreden Karoo Observatory (D. Bullis), Winobs (M. Shafer)

Report from ILEWG and Cape Canaveral Lunar Declaration 2008

NASA Astrophysics Data System (ADS)

Foing, B. H.

2009-04-01

We shall report on the ILEWG charter, goals and activities, on ICEUM "lunar declarations" and follow-up activities, with focus on societal questions, and the Cape Canaveral Lunar Declaration 2008. ILEWG charter: ILEWG , the International Lunar Exploration Working Group is a public forum created in 1994, sponsored by the world's space agencies to support "international cooperation towards a world strategy for the exploration and utilization of the Moon - our natural satellite". The charter of ILEWG is: - To develop an international strategy for the exploration of the Moon - To establish a forum and mechanisms for the communication and coordination of activities - To implement international coordination and cooperation - In order to facilitate communication among all interested parties ILEWG agrees to establish an electronic communication network for exchange of science, technology and programmatic information related to lunar activities ILEWG meets regularly, at least, once a year, and leads the organization of an International Conference in order to discuss the state of lunar exploration. Formal reports are given at COSPAR meetings and to space agencies. ILEWG is sponsored by the world's space agencies and is intended to serve three relevant groups: - actual members of the ILEWG, ie delegates and repre-sentatives of the participating Space Agencies and organizations - allowing them to discuss and possibly harmonize their draft concepts and plans - team members of the relevant space projects - allowing them to coordinate their internal work according to the guidelines provided by the Charter of the ILEWG - members of the general public and of the Lunar Explorer's Society who are interested and wish to be informed on the progress of the Moon projects and possibly contribute their own ideas ILEWG activities and working groups: ILEWG task groups include science, technology, human aspects, socio-economics, young explorers and outreach, programmatics, roadmaps and synergies with Mars exploration. Users can obtain information on how to participate, as well as details on the latest news and events regarding lunar exploration, forthcoming meetings, relevant reports and documents of importance for the work of the ILEWG, summary descriptions of current lunar exploration projects (such as SMART-1, Chang'E1, Selene, Chandrayaan-1, LRO, LCROSS) funded by various space agencies, and basic data on the Moon itself. Activities of the related space agencies and organizations can also be found. ILEWG has been organising International Conferences on Exploration and Utilisation of the Moon (ICEUM) since 1994, whose proceedings are published. It has also sponsored a number of activities, workshops, tasks groups and publications in collabora-tions with other organisations: COSPAR, space agencies, IAA, IAF, EGU (see references below). In accor-dance with its charter, ILEWG reports to COSPAR, and a summary was given at Montreal COSPAR2008 on ILEWG activities conducted since the previous COSPAR2006 assembly in Beijing. The recent ILEWG International Conference on Exploration and Utilisation of the Moon, were held respectively in Udaipur, India (ICEUM6, 2004), in Toronto, Canada (ICEUM7, 2005), in Beijing (ICEUM8, 2006), Sorrento (ICEUM9, 2007) and Port Canaveral (ICEUM10/LEAG/SRR, 2008 in conjunction with the NASA Lunar Exploration Analysis Groups and Space Resources Roundtable annual meetings). We'll report on the Cape Canaveral Lunar Declaration and on follow-up activities, in particular in coordination with space agencies, COSPAR and IAF. References: [1] 1st International Lunar Workshop, Balsiger H. et al., Editors, European Space Agency, 1994. ESA-SP-1170. [2] 2nd International Lunar Workshop, Kyoto, H. Mizutani, editor, Japan Space Forum Publisher, 1997. [3] 3rd International Lunar Workshop, Moscow 1998, E. Galimov, editor. [4] ICEUM4, ESTEC, 2000, ESA SP-462, B.H. Foing & M. Perry, editors. [5] ICEUM5, Hawaii Nov 2003, Durst S.M. et al, Editors, Vol 108, 1-576 pp, Science and Technology Series, American Astronautical Society, 2004. [6] ICEUM6, Udaipur 2004, Bhandari N., Editor, Journal Earth System Science, India, 114, No6, Dec 2005, pp. 573-841. [7] ICEUM7, Toronto Sept 2005, sci.esa.int/ilewg. [8] ICEUM8, Beijing July 2006, Journal of Chinese Society of Astronautics, Vol. 28 Sup., 2007, Ji W., Editor. [9] ICEUM9, Sorrento, Italy, Foing B., Espinasse S., Kosters G., Editors. http://sci.esa.int/iceum9, Dec. 2007), [11] Ehrenfreund, P., Foing, B.H., Cellino, A. Editors, The Moon and Near Earth Objects, ASR Vol 37, 1, 2006. [12] Foing, B.H. et al editors, 'Astronomy and Space Science from the Moon', ASR 14, 6, 1994. [13] Foing, B.H. et al, editor, Lunar Exploration, Planetary and Space Science, Vol 50, 14-15, 2002. [14] Foing, B.H., Heather, D. editors, 'Lunar Exploration 2000', ASR Vol 30, Nr 8, 2002. [15] Hunt-ress, W. et al 'The next steps in exploring deep space - A cosmic study by the IAA', Acta Astronautica, Vol 58, Issues 6-7, 2006, p302-377. [16] Ip W.-H., Foing, B.H., Masson Ph.L., editors, The Moon and Mars, ASR Vol 23, 11, 1999.

Effects of air current speed on gas exchange in plant leaves and plant canopies.

PubMed

Kitaya, Y; Tsuruyama, J; Shibuya, T; Yoshida, M; Kiyota, M

2003-01-01

To obtain basic data on adequate air circulation to enhance plant growth in a closed plant culture system in a controlled ecological life support system (CELSS), an investigation was made of the effects of the air current speed ranging from 0.01 to 1.0 m s-1 on photosynthesis and transpiration in sweetpotato leaves and photosynthesis in tomato seedlings canopies. The gas exchange rates in leaves and canopies were determined by using a chamber method with an infrared gas analyzer. The net photosynthetic rate and the transpiration rate increased significantly as the air current speeds increased from 0.01 to 0.2 m s-1. The transpiration rate increased gradually at air current speeds ranging from 0.2 to 1.0 m s-1 while the net photosynthetic rate was almost constant at air current speeds ranging from 0.5 to 1.0 m s-1. The increase in the net photosynthetic and transpiration rates were strongly dependent on decreased boundary-layer resistances against gas diffusion. The net photosynthetic rate of the plant canopy was doubled by an increased air current speed from 0.1 to 1.0 m s-1 above the plant canopy. The results demonstrate the importance of air movement around plants for enhancing the gas exchange in the leaf, especially in plant canopies in the CELSS. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Issues of exploration: human health and wellbeing during a mission to Mars.

PubMed

White, R J; Bassingthwaighte, J B; Charles, J B; Kushmerick, M J; Newman, D J

2003-01-01

Today, the tools are in our hands to enable us to travel away from our home planet and become citizens of the solar system. Even now, we are seriously beginning to develop the robust infrastructure that will make the 21st century the Century of Space Travel. But this bold step must be taken with due concern for the health, safety and wellbeing of future space explorers. Our long experience with space biomedical research convinces us that, if we are to deal effectively with the medical and biomedical issues of exploration, then dramatic and bold steps are also necessary in this field. We can no longer treat the human body as if it were composed of muscles, bones, heart and brain acting independently. Instead, we must lead the effort to develop a fully integrated view of the body, with all parts connected and fully interacting in a realistic way. This paper will present the status of current (2000) plans by the National Space Biomedical Research Institute to initiate research in this area of integrative physiology and medicine. Specifically, three example projects are discussed as potential stepping stones towards the ultimate goal of producing a digital human. These projects relate to developing a functional model of the human musculoskeletal system and the heart. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Planetary protection and the search for life beneath the surface of Mars

NASA Technical Reports Server (NTRS)

Mancinelli, Rocco L.

2003-01-01

The search for traces of extinct and extant life on Mars will be extended to beneath the surface of the planet. Current data from Mars missions suggesting the presence of liquid water early in Mars' history and mathematical modeling of the fate of water on Mars imply that liquid water may exist deep beneath the surface of Mars. This leads to the hypothesis that life may exist deep beneath the Martian surface. One possible scenario to look for life on Mars involves a series of unmanned missions culminating with a manned mission drilling deep into the Martian subsurface (approximately 3Km), collecting samples, and conducting preliminary analyses to select samples for return to earth. This mission must address both forward and back contamination issues, and falls under planetary protection category V. Planetary protection issues to be addressed include provisions stating that the inevitable deposition of earth microbes by humans should be minimized and localized, and that earth microbes and organic material must not contaminate the Martian subsurface. This requires that the drilling equipment be sterilized prior to use. Further, the collection, containment and retrieval of the sample must be conducted such that the crew is protected and that any materials returning to earth are contained (i.e., physically and biologically isolated) and the chain of connection with Mars is broken. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Issues of exploration: human health and wellbeing during a mission to Mars

NASA Technical Reports Server (NTRS)

White, R. J.; Bassingthwaighte, J. B.; Charles, J. B.; Kushmerick, M. J.; Newman, D. J.

2003-01-01

Today, the tools are in our hands to enable us to travel away from our home planet and become citizens of the solar system. Even now, we are seriously beginning to develop the robust infrastructure that will make the 21st century the Century of Space Travel. But this bold step must be taken with due concern for the health, safety and wellbeing of future space explorers. Our long experience with space biomedical research convinces us that, if we are to deal effectively with the medical and biomedical issues of exploration, then dramatic and bold steps are also necessary in this field. We can no longer treat the human body as if it were composed of muscles, bones, heart and brain acting independently. Instead, we must lead the effort to develop a fully integrated view of the body, with all parts connected and fully interacting in a realistic way. This paper will present the status of current (2000) plans by the National Space Biomedical Research Institute to initiate research in this area of integrative physiology and medicine. Specifically, three example projects are discussed as potential stepping stones towards the ultimate goal of producing a digital human. These projects relate to developing a functional model of the human musculoskeletal system and the heart. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Planetary protection and the search for life beneath the surface of Mars.

PubMed

Mancinelli, Rocco L

2003-01-01

The search for traces of extinct and extant life on Mars will be extended to beneath the surface of the planet. Current data from Mars missions suggesting the presence of liquid water early in Mars' history and mathematical modeling of the fate of water on Mars imply that liquid water may exist deep beneath the surface of Mars. This leads to the hypothesis that life may exist deep beneath the Martian surface. One possible scenario to look for life on Mars involves a series of unmanned missions culminating with a manned mission drilling deep into the Martian subsurface (approximately 3Km), collecting samples, and conducting preliminary analyses to select samples for return to earth. This mission must address both forward and back contamination issues, and falls under planetary protection category V. Planetary protection issues to be addressed include provisions stating that the inevitable deposition of earth microbes by humans should be minimized and localized, and that earth microbes and organic material must not contaminate the Martian subsurface. This requires that the drilling equipment be sterilized prior to use. Further, the collection, containment and retrieval of the sample must be conducted such that the crew is protected and that any materials returning to earth are contained (i.e., physically and biologically isolated) and the chain of connection with Mars is broken. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Search for cosmogenic Ar-42 in meteorites

NASA Astrophysics Data System (ADS)

Cini Castagnoli, G.; Cane, D.; Taricco, C.; Bhandari, N.

2003-04-01

We have evidence for decreasing galactic cosmic ray (GCR) flux in the past 3 centuries by a factor about two [1]. The measurements of the activity of cosmogenic 44Ti (T1/2 = 59.2 y) produced by GCR in stony meteorites that fell during the last two centuries are in good agreement with the calculated values and validate the decreasing trend of GCR flux. The measurements were obtained by an hyperpure (372 cm3) Ge-NaI(Tl) spectrometer operating in the Monte dei Cappuccini laboratory in Torino[2]. To further improve upon statistical precision of 44Ti data and also to be able to measure the 42Ar (T1/2 = 33 y) which is produced in even smaller amounts by GCR in meteorites, we have set up in the same laboratory a larger (581 cm3) hyperpure Ge detector operating in coincidence with a 100 kg NaI(Tl) crystal assembly. This should enable us to confirm the above results about GCR variations. We wish to acknowledge our deep gratitude to professor Bonino, deceased on September 29, 2002, to whom the assemblage of the new equipment is due. [1] G. Bonino, G. Cini Castagnoli, D. Cane, C. Taricco and N. Bhandari,Proc. XXVII Intern. Cosmic Ray Conf. (Hamburg, 2001) 3769-3772. [2] Bonino G., Cini Castagnoli G., Cane D., Taricco C., Bhandari N, textit {34th COSPAR Sci. Ass. Houston 2002 (Adv. Space Res.)}, in press

Genesis of the NASA Space Radiation Laboratory.

PubMed

Schimmerling, Walter

2016-06-01

A personal recollection of events leading up to the construction and commissioning of NSRL, including reference to precursor facilities and the development of the NASA Space Radiation Program. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Tide-associated biological rhythms of some White Sea littoral invertebrates.

PubMed

Gusev, O A; Golubev, A I

2001-01-01

We report the results from two years of laboratory observations of the tide-associated rhythms of activity of White Sea intertidal invertebrates, Mya arenaria (Bivalvia) and Gammarus finmarchicus (Amphipoda). The tidal associated activity of these invertebrates could not be estimate as a clear circatidal clock. Gammarus activity could be phase shifted by a 0.5 h exposure to turbulent water twice a day for 2-3 days. Mya's rhythm could be changed by a single drainage of aquariums lasting about 15 min. This kind of timing system may be a relatively primitive evolution feature. c2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Collisional PIC Simulations of Particles in Magnetic Fields

NASA Astrophysics Data System (ADS)

Peter, William

2003-10-01

Because of the long range of Coloumb forces, collisions with distant particles in plasmas are more important than collisions with near neighbors. In addition, many problems in space physics and magnetic confinement include regions of weak magnetic field where the MHD approximation breaks down. A particle-in-cell code based on the quiet direct simulation Monte-Carlo method(B. J. Albright, W. Daughton, D. Lemons, D. Winske, and M. E. Jones, Physics of Plasmas) 9, 1898 (2002). is being developed to study collisional (e.g., ν ˜ Ω) particle motion in magnetic fields. Primary application is to energetic particle loss in the radiation belts(K. Papadopoulos, COSPAR Meeting, Houston, TX, Oct., 2002.) at a given energy and L-shell. Other applications include trapping in rotating field-reversed configurations(N. Rostoker and A. Qerushi, Physics of Plasmas) 9, 3057 (2002)., and electron behavior in magnetic traps(V. Gorgadze, T. Pasquini, J. S. Wurtele, and J. Fajans, Bull. Am. Phys. Soc.) 47, 127 (2002).. The use of the random time-step method(W. Peter, Bull. Am. Phys. Soc.) 47, 52 (2002). to decrease simulation times by 1-2 orders of magnitude is also being studied.

Biological quarantine on international waters: an initiative for onboard protocols

NASA Astrophysics Data System (ADS)

Takano, Yoshinori; Yano, Hajime; Funase, Ryu; Sekine, Yasuhito; Takai, Ken

2012-07-01

The research vessel Chikyu is expanding new frontiers in science, technology, and international collaboration through deep-sea expedition. The Chikyu (length: 210 m, gross tonnage: 56752 tons) has advanced and comprehensive scientific research facilities. One of the scientific purposes of the vessel is to investigate into unexplored biosphere (i.e., undescribed extremophiles) on the Earth. Therefore, "the onboard laboratory" provides us systematic microbiological protocols with a physical containment situation. In parallel, the onboard equipments provide sufficient space for fifty scientists and technical support staff. The helicopter deck also supports various logistics through transporting by a large scale helicopter (See, http://www.jamstec.go.jp/chikyu/eng/). Since the establishment of Panel on Planetary Protection (PPP) in Committee on Space Research (COSPAR), we have an international consensus about the development and promulgation of planetary protection knowledge, policy, and plans to prevent the harmful effects of biological contamination on the Earth (e.g., Rummel, 2002). However, the matter to select a candidate location of initial quarantine at BSL4 level is often problematic. To answer the key issue, we suggest that international waters can be a meaningful option with several advantages to conduct initial onboard-biological quarantine investigation. Hence, the research vessel Chikyu is promising for further PPP requirements (e.g., Enceladus sample return project: Tsou et al., 2012). Rummel, J., Seeking an international consensus in planetary protection: COSPAR's planetary protection panel. Advances in Space Research, 30, 1573-1575 (2002). Tsou, P. et al. LIFE: Life Investigation For Enceladus - A Sample Return Mission Concept in Search for Evidence of Life. Astrobiology, in press.

Monte Carlo transport model comparison with 1A GeV accelerated iron experiment: heavy-ion shielding evaluation of NASA space flight-crew foodstuff

NASA Technical Reports Server (NTRS)

Stephens, D. L. Jr; Townsend, L. W.; Miller, J.; Zeitlin, C.; Heilbronn, L.

2002-01-01

Deep-space manned flight as a reality depends on a viable solution to the radiation problem. Both acute and chronic radiation health threats are known to exist, with solar particle events as an example of the former and galactic cosmic rays (GCR) of the latter. In this experiment Iron ions of 1A GeV are used to simulate GCR and to determine the secondary radiation field created as the GCR-like particles interact with a thick target. A NASA prepared food pantry locker was subjected to the iron beam and the secondary fluence recorded. A modified version of the Monte Carlo heavy ion transport code developed by Zeitlin at LBNL is compared with experimental fluence. The foodstuff is modeled as mixed nuts as defined by the 71st edition of the Chemical Rubber Company (CRC) Handbook of Physics and Chemistry. The results indicate a good agreement between the experimental data and the model. The agreement between model and experiment is determined using a linear fit to ordered pairs of data. The intercept is forced to zero. The slope fit is 0.825 and the R2 value is 0.429 over the resolved fluence region. The removal of an outlier, Z=14, gives values of 0.888 and 0.705 for slope and R2 respectively. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Spaceflight hardware for conducting plant growth experiments in space: the early years 1960-2000

NASA Technical Reports Server (NTRS)

Porterfield, D. M.; Neichitailo, G. S.; Mashinski, A. L.; Musgrave, M. E.

2003-01-01

The best strategy for supporting long-duration space missions is believed to be bioregenerative life support systems (BLSS). An integral part of a BLSS is a chamber supporting the growth of higher plants that would provide food, water, and atmosphere regeneration for the human crew. Such a chamber will have to be a complete plant growth system, capable of providing lighting, water, and nutrients to plants in microgravity. Other capabilities include temperature, humidity, and atmospheric gas composition controls. Many spaceflight experiments to date have utilized incomplete growth systems (typically having a hydration system but lacking lighting) to study tropic and metabolic changes in germinating seedlings and young plants. American, European, and Russian scientists have also developed a number of small complete plant growth systems for use in spaceflight research. Currently we are entering a new era of experimentation and hardware development as a result of long-term spaceflight opportunities available on the International Space Station. This is already impacting development of plant growth hardware. To take full advantage of these new opportunities and construct innovative systems, we must understand the results of past spaceflight experiments and the basic capabilities of the diverse plant growth systems that were used to conduct these experiments. The objective of this paper is to describe the most influential pieces of plant growth hardware that have been used for the purpose of conducting scientific experiments during the first 40 years of research. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Early development of fern gametophytes in microgravity

NASA Technical Reports Server (NTRS)

Roux, Stanley J.; Chatterjee, Ani; Hillier, Sheila; Cannon, Tom

2003-01-01

Dormant spores of the fern Ceratopteris richardii were flown on Shuttle mission STS-93 to evaluate the effects of micro-g on their development and on their pattern of gene expression. Prior to flight the spores were sterilized and sown into one of two environments: (1) Microscope slides in a video-microscopy module; and (2) Petri dishes. All spores were then stored in darkness until use. Spore germination was initiated on orbit after exposure to light. For the spores on microscope slides, cell level changes were recorded through the clear spore coat of the spores by video microscopy. After their exposure to light, spores in petri dishes were frozen in orbit at four different time points during which on earth gravity fixes the polarity of their development. Spores were then stored frozen in Biological Research in Canister units until recovery on earth. The RNAs from these cells and from 1-g control cells were extracted and analyzed on earth after flight to assay changes in gene expression. Video microscopy results revealed that the germinated spores developed normally in microgravity, although the polarity of their development, which is guided by gravity on earth, was random in space. Differential Display-PCR analyses of RNA extracted from space-flown cells showed that there was about a 5% change in the pattern of gene expression between cells developing in micro-g compared to those developing on earth. c2002 Published by Elsevier Science Ltd on behalf of COSPAR.

Long-term changes in amphetamine-induced reinforcement and aversion in rats following exposure to 56Fe particle

NASA Technical Reports Server (NTRS)

Rabin, B. M.; Joseph, J. A.; Shukitt-Hale, B.

2003-01-01

Exposing rats to heavy particles produces alterations in the functioning of dopaminergic neurons and in the behaviors that depend upon the integrity of the dopaminergic system. Two of these dopamine-dependent behaviors include amphetamine-induced reinforcement, measure using the conditioned place preference procedure, and amphetamine-induced reinforcement, measured using the conditioned place preference procedure, and amphetamine-induced aversion, measured using the conditioned taste aversion. Previous research has shown that exposing rats to 1.0 Gy of 1GeV/n 56Fe particles produced a disruption of an amphetamine-induced taste aversion 3 days following exposure, but produced an apparent enhancement of the aversion 112 days following exposure. The present experiments were designed to provide a further evaluation of these results by examining taste aversion learning 154 days following exposure to 1.0 Gy 56Fe particles and to establish the convergent validity of the taste aversion results by looking at the effects of exposure on the establishment of an amphetamine-induced conditioned place preference 3, 7, and 16 weeks following irradiation. The taste aversion results failed to confirm the apparent enhancement of the amphetamine-induced CTA observed in the prior experiment. However, exposure to 56Fe particles prevented the acquisition of amphetamine-induced place preference at all three-time intervals. The results are interpreted as indicating that exposure to heavy particles can produce long-term changes in behavioral functioning. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Spaceflight hardware for conducting plant growth experiments in space: the early years 1960-2000.

PubMed

Porterfield, D M; Neichitailo, G S; Mashinski, A L; Musgrave, M E

2003-01-01

The best strategy for supporting long-duration space missions is believed to be bioregenerative life support systems (BLSS). An integral part of a BLSS is a chamber supporting the growth of higher plants that would provide food, water, and atmosphere regeneration for the human crew. Such a chamber will have to be a complete plant growth system, capable of providing lighting, water, and nutrients to plants in microgravity. Other capabilities include temperature, humidity, and atmospheric gas composition controls. Many spaceflight experiments to date have utilized incomplete growth systems (typically having a hydration system but lacking lighting) to study tropic and metabolic changes in germinating seedlings and young plants. American, European, and Russian scientists have also developed a number of small complete plant growth systems for use in spaceflight research. Currently we are entering a new era of experimentation and hardware development as a result of long-term spaceflight opportunities available on the International Space Station. This is already impacting development of plant growth hardware. To take full advantage of these new opportunities and construct innovative systems, we must understand the results of past spaceflight experiments and the basic capabilities of the diverse plant growth systems that were used to conduct these experiments. The objective of this paper is to describe the most influential pieces of plant growth hardware that have been used for the purpose of conducting scientific experiments during the first 40 years of research. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Monte Carlo transport model comparison with 1A GeV accelerated iron experiment: heavy-ion shielding evaluation of NASA space flight-crew foodstuff.

PubMed

Stephens, D L; Townsend, L W; Miller, J; Zeitlin, C; Heilbronn, L

2002-01-01

Deep-space manned flight as a reality depends on a viable solution to the radiation problem. Both acute and chronic radiation health threats are known to exist, with solar particle events as an example of the former and galactic cosmic rays (GCR) of the latter. In this experiment Iron ions of 1A GeV are used to simulate GCR and to determine the secondary radiation field created as the GCR-like particles interact with a thick target. A NASA prepared food pantry locker was subjected to the iron beam and the secondary fluence recorded. A modified version of the Monte Carlo heavy ion transport code developed by Zeitlin at LBNL is compared with experimental fluence. The foodstuff is modeled as mixed nuts as defined by the 71st edition of the Chemical Rubber Company (CRC) Handbook of Physics and Chemistry. The results indicate a good agreement between the experimental data and the model. The agreement between model and experiment is determined using a linear fit to ordered pairs of data. The intercept is forced to zero. The slope fit is 0.825 and the R2 value is 0.429 over the resolved fluence region. The removal of an outlier, Z=14, gives values of 0.888 and 0.705 for slope and R2 respectively. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Development and research program for a soil-based bioregenerative agriculture system to feed a four person crew at a Mars base.

PubMed

Silverstone, S; Nelson, M; Alling, A; Allen, J

2003-01-01

For humans to survive during long-term missions on the Martian surface, bioregenerative life support systems including food production will decrease requirements for launch of Earth supplies, and increase mission safety. It is proposed that the development of "modular biospheres"--closed system units that can be air-locked together and which contain soil-based bioregenerative agriculture, horticulture, with a wetland wastewater treatment system is an approach for Mars habitation scenarios. Based on previous work done in long-term life support at Biosphere 2 and other closed ecological systems, this consortium proposes a research and development program called Mars On Earth(TM) which will simulate a life support system designed for a four person crew. The structure will consist of 6 x 110 square meter modular agricultural units designed to produce a nutritionally adequate diet for 4 people, recycling all air, water and waste, while utilizing a soil created by the organic enrichment and modification of Mars simulant soils. Further research needs are discussed, such as determining optimal light levels for growth of the necessary range of crops, energy trade-offs for agriculture (e.g. light intensity vs. required area), capabilities of Martian soils and their need for enrichment and elimination of oxides, strategies for use of human waste products, and maintaining atmospheric balance between people, plants and soils. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Physiological characterization of gravitaxis in Euglena gracilis and Astasia longa studied on sounding rocket flights.

PubMed

Richter, P R; Lebert, M; Tahedl, H; Hader, D P

2001-01-01

Euglena gracilis is a photosynthetic, unicellular flagellate found in eutrophic freshwater habitats. The organisms control their vertical position in the water column using gravi- and phototaxis. Recent experiments demonstrated that negative gravitaxis cannot be explained by passive buoyancy but by an active physiological mechanism. During space experiments, the threshold of gravitaxis was determined to be between 0.08 and 0.12 x g. A strong correlation between the applied acceleration and the intracellular cAMP and Ca2+ was observed. The results support the hypothesis, that the cell body of Euglena, which is denser than the surrounding medium exerts a pressure onto the lower membrane and activates mechanosensitive Ca2+ channels. Changes in the membrane potential and the cAMP concentration are most likely subsequent elements in a signal transduction chain, which results in reorientation strokes of the flagellum. c 2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Report on the 2015 COSPAR Panel on Planetary Protection Colloquium

NASA Astrophysics Data System (ADS)

Hipkin, Victoria; Kminek, Gerhard

2016-07-01

In consultation with the COSPAR Scientific Commissions B (Space Studies of the Earth-Moon System, Planets, and Small Bodies of the Solar System) and F (Life Sciences as Related to Space), the COSPAR Panel on Planetary Protection organised a colloquium at the International Space Science Institute (ISSI) in Bern, Switzerland, in September 2015, to cover two pertinent topics: * Icy moon sample return planetary protection requirements * Mars Special Regions planetary protection requirements These two topics were addressed in two separate sessions. Participation from European, North American and Japanese scientists reflected broad expertise from the respective COSPAR Commissions, recent NASA MEPAG Science Analysis Group and National Academies of Sciences, Engineering, and Medicine/European Science Foundation Mars Special Regions Review Committee. The recommendations described in this report are based on discussions that took place during the course of the colloquium and reflect a consensus of the colloquium participants that participated in the two separate sessions. These recommendations are brought to the 2016 COSPAR Scientific Assembly for further input and discussion as part of the recognised process for updating COSPAR Planetary Protection Policy.

Pigment composition and concentrations within the plant (Ceratophyllum demersum L.) component of the STS-89 C.E.B.A.S. Mini-Module spaceflight experiment

NASA Technical Reports Server (NTRS)

Voeste, D.; Levine, L. H.; Levine, H. G.; Blum, V.; Wheeler, R. M. (Principal Investigator)

2003-01-01

The Closed Equilibrated Biological Aquatic System (C.E.B.A.S.) Mini-Module, a Space Shuttle middeck locker payload which supports a variety of aquatic inhabitants (fish, snails, plants and bacteria) in an enclosed 8.6 L chamber, was tested for its biological stability in microgravity. The aquatic plant, Ceratophyllum demersum L., was critical for the vitality and functioning of this artificial mini-ecosystem. Its photosynthetic pigment concentrations were of interest due to their light harvesting and protective functions. "Post-flight" chlorophyll and carotenoid concentrations within Ceratophyllum apical segments were directly related to the quantities of light received in the experiments, with microgravity exposure (STS-89) failing to account for any significant deviation from ground control studies. Published by Elsevier Science Ltd on behalf of COSPAR.

Consolidated Checklist for C4 40 CFR 263

EPA Pesticide Factsheets

No final rules affecting 40 CFR Part 263 were promulgated between June 30, 2002 and December 31, 2002, therefore, this Consolidated Checklist corresponds to 40 CFR Part 263 as published on July 1, 2002.

Consolidated Checklist for C3 40 CFR 262

EPA Pesticide Factsheets

No final rules affecting 40 CFR Part 262 were promulgated between June 30, 2002 and December 31, 2002, therefore, this Consolidated Checklist corresponds to 40 CFR Part 262 as published on July 1, 2002.

Pancreas of C57 black mice after long-term space flight (Bion-M1 Space Mission).

PubMed

Proshchina, A E; Krivova, Y S; Saveliev, S C

2015-11-01

In this study, we analysed the pancreases of C57BL/6N mice in order to estimate the effects of long-term space flights. Mice were flown aboard the Bion-M1 biosatellite, or remained on ground in the control experiment that replicated environmental and housing conditions in the spacecraft. Vivarium control group was used to account for housing effects. Each of the groups included mice designated for recovery studies. Mice pancreases were dissected for histological and immunohistochemical examinations. Using a morphometry and statistical analysis, a strong correlation between the mean islet size and the mean body weight was revealed in all groups. Therefore, we propose that hypokinesia and an increase in nutrition play an important role in alterations of the endocrine pancreas, both in space flight and terrestrial conditions. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Performance of the CELSS Antarctic Analog Project (CAAP) crop production system.

PubMed

Bubenheim, D L; Schlick, G; Wilson, D; Bates, M

2003-01-01

Regenerative life support systems potentially offer a level of self-sufficiency and a decrease in logistics and associated costs in support of space exploration and habitation missions. Current state-of-the-art in plant-based, regenerative life support requires resources in excess of allocation proposed for candidate mission scenarios. Feasibility thresholds have been identified for candidate exploration missions. The goal of this paper is to review recent advances in performance achieved in the CELSS Antarctic Analog Project (CAAP) in light of the likely resource constraints. A prototype CAAP crop production chamber has been constructed and operated at the Ames Research Center. The chamber includes a number of unique hardware and software components focused on attempts to increase production efficiency, increase energy efficiency, and control the flow of energy and mass through the system. Both single crop, batch production and continuous cultivation of mixed crops production studies have been completed. The crop productivity as well as engineering performance of the chamber are described. For each scenario, energy required and partitioned for lighting, cooling, pumping, fans, etc. is quantified. Crop production and the resulting lighting efficiency and energy conversion efficiencies are presented. In the mixed-crop scenario, with 27 different crops under cultivation, 17 m2 of crop area provided a mean of 515 g edible biomass per day (85% of the approximate 620 g required for one person). Enhanced engineering and crop production performance achieved with the CAAP chamber, compared with current state-of-the-art, places plant-based life support systems at the threshold of feasibility. c2002 Published by Elsevier Science Ltd on behalf of COSPAR.

Performance of the CELSS Antarctic Analog Project (CAAP) crop production system

NASA Technical Reports Server (NTRS)

Bubenheim, D. L.; Schlick, G.; Wilson, D.; Bates, M.

2003-01-01

Regenerative life support systems potentially offer a level of self-sufficiency and a decrease in logistics and associated costs in support of space exploration and habitation missions. Current state-of-the-art in plant-based, regenerative life support requires resources in excess of allocation proposed for candidate mission scenarios. Feasibility thresholds have been identified for candidate exploration missions. The goal of this paper is to review recent advances in performance achieved in the CELSS Antarctic Analog Project (CAAP) in light of the likely resource constraints. A prototype CAAP crop production chamber has been constructed and operated at the Ames Research Center. The chamber includes a number of unique hardware and software components focused on attempts to increase production efficiency, increase energy efficiency, and control the flow of energy and mass through the system. Both single crop, batch production and continuous cultivation of mixed crops production studies have been completed. The crop productivity as well as engineering performance of the chamber are described. For each scenario, energy required and partitioned for lighting, cooling, pumping, fans, etc. is quantified. Crop production and the resulting lighting efficiency and energy conversion efficiencies are presented. In the mixed-crop scenario, with 27 different crops under cultivation, 17 m2 of crop area provided a mean of 515 g edible biomass per day (85% of the approximate 620 g required for one person). Enhanced engineering and crop production performance achieved with the CAAP chamber, compared with current state-of-the-art, places plant-based life support systems at the threshold of feasibility. c2002 Published by Elsevier Science Ltd on behalf of COSPAR.

Survival of microorganisms in space protected by meteorite material: results of the experiment 'EXOBIOLOGIE' of the PERSEUS mission.

PubMed

Rettberg, P; Eschweiler, U; Strauch, K; Reitz, G; Horneck, G; Wanke, H; Brack, A; Barbier, B

2002-01-01

During the early evolution of life on Earth, before the formation of a protective ozone layer in the atmosphere, high intensities of solar UV radiation of short wavelengths could reach the surface of the Earth. Today the full spectrum of solar UV radiation is only experienced in space, where other important space parameters influence survival and genetic stability additionally, like vacuum, cosmic radiation, temperature extremes, microgravity. To reach a better understanding of the processes leading to the origin, evolution and distribution of life we have performed space experiments with microorganisms. The ability of resistant life forms like bacterial spores to survive high doses of extraterrestrial solar UV alone or in combination with other space parameters, e.g. vacuum, was investigated. Extraterrestrial solar UV was found to have a thousand times higher biological effectiveness than UV radiation filtered by stratospheric ozone concentrations found today on Earth. The protective effects of anorganic substances like artificial or real meteorites were determined on the MIR station. In the experiment EXOBIOLOGIE of the French PERSEUS mission (1999) it was found that very thin layers of anorganic material did not protect spores against the deleterious effects of energy-rich UV radiation in space to the expected amount, but that layers of UV radiation inactivated spores serve as a UV-shield by themselves, so that a hypothetical interplanetary transfer of life by the transport of microorganisms inside rocks through the solar system cannot be excluded, but requires the shielding of a substantial mass of anorganic substances. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

The International Reference Ionosphere 2012 - a model of international collaboration

NASA Astrophysics Data System (ADS)

Bilitza, Dieter; Altadill, David; Zhang, Yongliang; Mertens, Chris; Truhlik, Vladimir; Richards, Phil; McKinnell, Lee-Anne; Reinisch, Bodo

2014-02-01

The International Reference Ionosphere (IRI) project was established jointly by the Committee on Space Research (COSPAR) and the International Union of Radio Science (URSI) in the late sixties with the goal to develop an international standard for the specification of plasma parameters in the Earth's ionosphere. COSPAR needed such a specification for the evaluation of environmental effects on spacecraft and experiments in space, and URSI for radiowave propagation studies and applications. At the request of COSPAR and URSI, IRI was developed as a data-based model to avoid the uncertainty of theory-based models which are only as good as the evolving theoretical understanding. Being based on most of the available and reliable observations of the ionospheric plasma from the ground and from space, IRI describes monthly averages of electron density, electron temperature, ion temperature, ion composition, and several additional parameters in the altitude range from 60 km to 2000 km. A working group of about 50 international ionospheric experts is in charge of developing and improving the IRI model. Over time as new data became available and new modeling techniques emerged, steadily improved editions of the IRI model have been published. This paper gives a brief history of the IRI project and describes the latest version of the model, IRI-2012. It also briefly discusses efforts to develop a real-time IRI model. The IRI homepage is at http://IRImodel.org.

The carbon dioxide cycle

USGS Publications Warehouse

James, P.B.; Hansen, G.B.; Titus, T.N.

2005-01-01

The seasonal CO2 cycle on Mars refers to the exchange of carbon dioxide between dry ice in the seasonal polar caps and gaseous carbon dioxide in the atmosphere. This review focuses on breakthroughs in understanding the process involving seasonal carbon dioxide phase changes that have occurred as a result of observations by Mars Global Surveyor. ?? 2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

The minimal cost of life in space.

PubMed

Drysdale, A E; Rutkze, C J; Albright, L D; LaDue, R L

2004-01-01

The cost of keeping people alive in space is assessed from a theoretical viewpoint and using two actual designs for plant growth systems. While life support is theoretically not very demanding, our ability to implement life support is well below theoretical limits. A theoretical limit has been calculated from requirements and the state of the art for plant growth has been calculated using data from the BIO-Plex PDR and from the Cornell CEA prototype system. The very low efficiency of our current approaches results in a high mission impact, though we can still see how to get a significant reduction in cost of food when compared to supplying it from Earth. Seeing the distribution of costs should allow us to improve our current designs. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Applied superconductivity and superfluidity for the exploration of the Moon and Mars

NASA Technical Reports Server (NTRS)

Chui, Talso C P.; Hahn, Inseob; Penanen, Konstantin; Zhong, Fang; Strayer, Donald

2005-01-01

We discuss how superconductivity and superfluidity can be applied to solve the challenges in the exploration of the Moon and Mars. High sensitivity instruments using phenomena of superconductivity and superfluidity can potentially make significant contributions to the fields of navigation, automation, habitation, and resource location. Using the quantum nature of superconductivity, lightweight and very sensitive diagnostic tools can be made to monitor the health of astronauts. Moreover, the Moon and Mars offer a unique environment for scientific exploration. We also discuss how powerful superconducting instruments may enable scientists to seek answers to several profound questions about nature. These answers will not only deepen our appreciation of the universe, they may also open the door to paradigm-shifting technologies. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

The minimal cost of life in space

NASA Technical Reports Server (NTRS)

Drysdale, A. E.; Rutkze, C. J.; Albright, L. D.; LaDue, R. L.

2004-01-01

The cost of keeping people alive in space is assessed from a theoretical viewpoint and using two actual designs for plant growth systems. While life support is theoretically not very demanding, our ability to implement life support is well below theoretical limits. A theoretical limit has been calculated from requirements and the state of the art for plant growth has been calculated using data from the BIO-Plex PDR and from the Cornell CEA prototype system. The very low efficiency of our current approaches results in a high mission impact, though we can still see how to get a significant reduction in cost of food when compared to supplying it from Earth. Seeing the distribution of costs should allow us to improve our current designs. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Applied superconductivity and superfluidity for the exploration of the Moon and Mars.

PubMed

Chui, Talso C P; Hahn, Inseob; Penanen, Konstantin; Zhong, Fang; Strayer, Donald

2005-01-01

We discuss how superconductivity and superfluidity can be applied to solve the challenges in the exploration of the Moon and Mars. High sensitivity instruments using phenomena of superconductivity and superfluidity can potentially make significant contributions to the fields of navigation, automation, habitation, and resource location. Using the quantum nature of superconductivity, lightweight and very sensitive diagnostic tools can be made to monitor the health of astronauts. Moreover, the Moon and Mars offer a unique environment for scientific exploration. We also discuss how powerful superconducting instruments may enable scientists to seek answers to several profound questions about nature. These answers will not only deepen our appreciation of the universe, they may also open the door to paradigm-shifting technologies. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

COSPAR Workshop on Planetary Protection for Titan and Ganymede

NASA Astrophysics Data System (ADS)

Rummel, J. D.; Raulin, F.; Ehrenfreund, P.

2010-06-01

During the deliberations of the COSPAR Workshop on Planetary Protection for Outer Planet Satellites and Small Solar System Bodies (Rummel et al., 2009), held in Vienna in April 2009, a number of bodies in the outer Solar System were identified as being potentially in the "II+" category consistent with the COSPAR categorization scheme, referring to a body that is of interest to chemical evolution and the origin of life, but whose potential to support living organisms is undecided, including at least Titan, Ganymede, Triton, and the Pluto-Charon system (see Appendix C). Of these objects, Titan is the highest priority target for a near-term robotic flagship mission and Ganymede is also the subject of flagship mission interest. To address the concerns that were raised in Vienna about the categorization of Titan and Ganymede (as "II+") required another dedicated workshop to concentrate on those two bodies, a meeting was planned and held jointly by NASA, ESA, and COSPAR during the winter of 2009- 2010. This workshop included additional experts on Titan and Ganymede who were not able to participate in the Vienna meeting, and allowed the attendees to inspect detailed information about the most recent Cassini-Huygens results as well as the most current interpretation of the data available for both Titan and Ganymede. The goal of this workshop was to resolve the mission category for Titan and Ganymede and to develop a consensus on the II versus II+ dichotomy, taking into account both the conservative nature of planetary protection policy and the physical constraints on the Titan system and on Ganymede - the two largest moons in our solar system. This report summarizes the findings and recommendations from the workshop. The document will be distributed to the COSPAR Planetary Protection panel for consideration prior to the next General Assembly meeting in Bremen (Germany) during July 2010. Results from the Titan/Ganymede study will also be coordinated in a larger evaluation of outer planet icy satellites that has been requested from the US National Research Council.

COSPAR for Dummies: History

NASA Astrophysics Data System (ADS)

Viso, Michel

The committee for Space research was established by the International Council of Scientific Union during the year following the launch of Sputnik 1(October 4th, 1957) which opened the space Era. The committee was the main point of contact in the, then, bipolarized world between scientists from the eastern and western countries. This committee remained the main and sometimes the sole point of contact for the scientists from both parties. During this period, called “cold war” the exchanges were very difficult and language barrier was also a major obstacle in exchanges. Beyond its former, strong political significance, COSPAR aims at promoting the space research, the exchanges of results, information. It was often the starting point of actual scientific cooperation. Even COSPAR has a continuous activity, the focal point for most of the space scientists is the general assembly which was held every year from 1958 up to 1980, then once every other year. The governing body is composed of representatives of various institutions and scientific unions. With the present structure by commissions and sub-commissions, the general assembly are quite big events with numerous scientists working in parallel sessions. The number of oral presentations and poster is continuously increasing. COSPAR is the best and perhaps the unique place for space scientists to exchange and enlarge their vision of space science. While structured in specialized commissions individuals can build up their own interdisciplinary program. Beyond the commissions there are several groups of interests, cross disciplinary and not linked to a single scientific domain: these are the panels. Some are supposed to be transient; some are supposed to be indefinite. The panels can propose advices and recommendations which could be used by the space agencies or other institutions. The officers of the panels are appointed by the COSPAR Bureau. COSPAR is an international cooperative body for scientists. It is the ideal place for young scientist to extend their knowledge not only in their own field but also in other disciplines to prepare their own future and their future research. COSPAR is editing two scientific journals and a bulletin. Just use them!! You are scientists, you are interested in space sciences or science in space; COSPAR is good for you!

Consolidated Checklist for C8 Title 40 of the Code of Federal Regulations (CFR) Part 268

EPA Pesticide Factsheets

This Consolidated Checklist corresponds to the 40 CFR Part 268, published on July 1, 2002, and as amended by the following final rules: 67 FR 48393, July 24, 2002 (Revision Checklist 200); and 67 FR 62618, October 7, 2002 (Revision Checklist 201).

Overview of the Liulin type instruments for space radiation measurement and their scientific results.

PubMed

Dachev, T P; Semkova, J V; Tomov, B T; Matviichuk, Yu N; Dimitrov, P G; Koleva, R T; Malchev, St; Bankov, N G; Shurshakov, V A; Benghin, V V; Yarmanova, E N; Ivanova, O A; Häder, D-P; Lebert, M; Schuster, M T; Reitz, G; Horneck, G; Uchihori, Y; Kitamura, H; Ploc, O; Cubancak, J; Nikolaev, I

2015-01-01

Ionizing radiation is recognized to be one of the main health concerns for humans in the space radiation environment. Estimation of space radiation effects on health requires the accurate knowledge of the accumulated absorbed dose, which depends on the global space radiation distribution, solar cycle and local shielding generated by the 3D mass distribution of the space vehicle. This paper presents an overview of the spectrometer-dosimeters of the Liulin type, which were developed in the late 1980s and have been in use since then. Two major measurement systems have been developed by our team. The first one is based on one silicon detector and is known as a Liulin-type deposited energy spectrometer (DES) (Dachev et al., 2002, 2003), while the second one is a dosimetric telescope (DT) with two or three silicon detectors. The Liulin-type instruments were calibrated using a number of radioactive sources and particle accelerators. The main results of the calibrations are presented in the paper. In the last section of the paper some of the most significant scientific results obtained in space and on aircraft, balloon and rocket flights since 1989 are presented. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Plant growth during the Greenhouse II experiment on the Mir orbital station

NASA Technical Reports Server (NTRS)

Salisbury, F. B.; Campbell, W. F.; Carman, J. G.; Bingham, G. E.; Bubenheim, D. L.; Yendler, B.; Sytchev, V.; Levinskikh, M. A.; Ivanova, I.; Chernova, L.;

Analysis of the archaeal sub-seafloor community at Suiyo Seamount on the Izu-Bonin Arc.

PubMed

Hara, Kurt; Kakegawa, Takeshi; Yamashiro, Kan; Maruyama, Akihiko; Ishibashi, Jun-Ichiro; Marumo, Katsumi; Urabe, Tetsuro; Yamagishi, Akihiko

2005-01-01

A sub-surface archaeal community at the Suiyo Seamount in the Western Pacific Ocean was investigated by 16S rRNA gene sequence and whole-cell in situ hybridization analyses. In this study, we drilled and cased holes at the hydrothermal area of the seamount to minimize contamination of the hydrothermal fluid in the sub-seafloor by penetrating seawater. PCR clone analysis of the hydrothermal fluid samples collected from a cased hole indicated the presence of chemolithoautotrophic primary biomass producers of Archaeoglobales and the Methanococcales-related archaeal HTE1 group, both of which can utilize hydrogen as an electron donor. We discuss the implication of the microbial community on the early history of life and on the search for extraterrestrial life. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

Using explanatory crop models to develop simple tools for Advanced Life Support system studies

NASA Technical Reports Server (NTRS)

Cavazzoni, J.

2004-01-01

System-level analyses for Advanced Life Support require mathematical models for various processes, such as for biomass production and waste management, which would ideally be integrated into overall system models. Explanatory models (also referred to as mechanistic or process models) would provide the basis for a more robust system model, as these would be based on an understanding of specific processes. However, implementing such models at the system level may not always be practicable because of their complexity. For the area of biomass production, explanatory models were used to generate parameters and multivariable polynomial equations for basic models that are suitable for estimating the direction and magnitude of daily changes in canopy gas-exchange, harvest index, and production scheduling for both nominal and off-nominal growing conditions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Radiation-induced bystander effect and adaptive response in mammalian cells

NASA Technical Reports Server (NTRS)

Zhou, H.; Randers-Pehrson, G.; Waldren, C. A.; Hei, T. K.

2004-01-01

Two conflicting phenomena, bystander effect and adaptive response, are important in determining the biological responses at low doses of radiation and have the potential to impact the shape of the dose-response relationship. Using the Columbia University charged-particle microbeam and the highly sensitive AL cell mutagenic assay, we show here that non-irradiated cells acquire mutagenesis through direct contact with cells whose nuclei have been traversed with a single alpha particle each. Pretreatment of cells with a low dose of X-rays four hours before alpha particle irradiation significantly decreased this bystander mutagenic response. Results from the present study address some of the fundamental issues regarding both the actual target and radiation dose effect and can contribute to our current understanding in radiation risk assessment. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Report from ILEWG to the COSPAR Panel on Exploration

NASA Astrophysics Data System (ADS)

Foing, Bernard H.

The International Lunar Exploration Working Group (ILEWG) was established in April 1995 at a meeting in Hamburg, Germany. As established in its charter, this working group reports to COSPAR and is charged with developing an international strategy for the exploration of the Moon. It discusses coordination between missions, and a road map for future international lunar exploration and utilisation. It fosters information exchange or potential and real future lunar robotic and human missions, as well as for new scientific and exploration information about the Moon. ILEWG was used to feed forward results from lunar missions such as SMART1 to the next ones, and we look now to integrate lessons from all recent orbiters and landers, for the upcoming landers, sample return missions, and human activities. We give a report on ILEWG community activities, refer to COSPAR and ILEWG ICEUM and lunar conferences and declarations [1-18], and discuss the follow-up of GLUC/ICEUM11 declaration relevant to COSPAR PEX*. References: [1] 1st International Lunar Workshop, Balsiger H. et al., Editors, European Space Agency, 1994. ESA-SP-1170. [2] 2nd International Lunar Workshop, Kyoto, H. Mizutani, editor, Japan Space Forum Publisher, 1997. [3] 3rd International Lunar Workshop, Moscow 1998, E. Galimov, editor. [4] ICEUM4, ESTEC, 2000, ESA SP-462, B.H. Foing & M. Perry, editors. [5] ICEUM5, Hawaii Nov 2003, Durst S.M. et al, Editors, Vol 108, 1-576 pp, Science and Technology Series, American Astronautical Society, 2004. [6] ICEUM6, Udaipur 2004, Bhandari N., Editor, Journal Earth Sys-tem Science, India, 114, No6, Dec 2005, pp. 573-841. [7] ICEUM7, Toronto Sept 2005, sci.esa.int/ilewg. [8] ICEUM8, Beijing July 2006, Journal of Chinese Society of Astronautics, Vol. 28 Sup., 2007, Ji W., Editor. [9] ICEUM9, Sorrento, Italy, Foing B., Espinasse S., Kosters G., Editors. http://sci.esa.int/iceum9, Dec. 2007), [11] Ehrenfreund, P., Foing, B.H., Cellino, A. Editors, The Moon and Near Earth Objects, ASR Vol 37, 1, 2006. [12] Foing, B.H. et al editors, 'Astronomy and Space Science from the Moon', ASR 14, 6, 1994. [13] Ip W.-H., Foing, B.H., Masson Ph.L., editors, The Moon and Mars, ASR Vol 23, 11, 1999. [14] Foing, B.H. et al, editor, Lunar Exploration, Planetary and Space Science, Vol 50, 14-15, 2002. [15] Foing, B.H., Heather, D. editors, 'Lunar Exploration 2000', ASR Vol 30, Nr 8, 2002. [16] Huntress, W. et al 'The next steps in exploring deep space - A cosmic study by the IAA', Acta Astronautica, Vol 58, Issues 6-7, 2006, p302-377. [17] http://sci.esa.int/ilewg/43654-declaration-iceum10-leag-srr-florida-2008/ [18] Ehrenfreund P. et al (COSPAR planetary exploration panel report) 2012, ASR Vol 49, Nr 1, pp. 2-48. *Relevant extract from GLUC/ICEUM11 declaration: “467 International Lunar Explorers, registered delegates from 26 countries, assembled at GLUC Global Lunar Conference including the 11th ILEWG Conference on Exploration and Utilisation of the Moon (ICEUM11) in Beijing." "1. Science and exploration (related GLUC/ICEUM11 recommendations will be addressed at COSPAR B0.1 Lunar science and exploration session) 2. Technologies and resources - A number of robotic missions to the Moon are now undertaken independently by various nations, with a degree of exchange of information and co-ordination. That should increase towards real co-operation, still allowing areas of competition for keeping the process active, cost-effective and faster. - Lunar landers, pressurized lunar rover projects as presented from Europe, Asia and America are important steps that can create opportunities for international collaboration, within a coordinated village of robotic precursors and assistants to crew missions. - We have to think about development, modernization of existing navigation capabilities, and provision of lunar positioning, navigation and data relay assets to support future robotic and human exploration. New concepts and new methods for transportation have attracted much attention and are of great potential. 3. Infrastructures and human aspects - It is recommended to have technical sessions and activities dealing with different aspects of human adaptation to space environments, the modeling of sub-systems, microbial protection and use of inflatable technologies - While the Moon is the best and next logical step in human exploration, we should make best use of the space stations as stepping stones for exploration and human spaceflight beyond Low Earth Orbit. - Further research is needed on lunar dust aspects in regard to humans and interaction with habitats. We note high interest in CELSS for Moon and Mars bases, and recommend further research and development. - We recommend the development and use of terrestrial analogues research sites and facilities, for technology demonstrations, comparative geology and human performance research, and public engagement. We endorse the proposal of development of a site at La Reunion for international Moon-Mars analogue research. 4. Moon, Space, Society and Young Explorers - We consider that the current legal regime as set out in the Outer Space Treaty and the Moon agreement are satisfactory for current and future missions, but may require further clarification for future exploration. Issues of transparency and security will need to be addressed. - Great things are happening for Young Lunar Explorers, with inspiring missions and hands-on activities as coordinated by ILEWG. Lunar exploration is encouraging students of all ages to pursue higher education. - More possibilities for participatory engagement should be offered to the society for example via inter-disciplinary activities with the humanities. - We appreciate the work from COSPAR panel on Exploration PEX that should be shared further. - Continued cooperation should be enforced at all levels. The space community feels strongly that joining the forces of space faring nations to explore the Moon should be seriously implemented, with the views of expanding a Global Robotic Village and building in the long run a Manned International Lunar Base.” “We, the participants of the GLUC-ICEUM11 conference, commit to an enhanced global cooperation towards international lunar exploration for the benefit of humankind. Endorsed by the delegates of GLUC-ICEUM11”

Imaging Gravity Waves in Lower Stratospheric AMSU-A Radiances. Part 2: Validation Case Study

DTIC Science & Technology

2006-08-14

Ortland, 2003) and temperatures from the 1986 COSPAR International Reference Atmosphere (CIRA; Fleming et al., 1990): for algorithm details, see Eck ...Soc., 130, 1505–1530, 2004. Webster, S., Brown, A. R., Cameron , D. R., and Jones, C. P.: Im- provements to the representation of orography in the Met

From organic chemistry in small bodies of the solar system to low temperature chemistry in the universe. Preface.

PubMed

Levasseur-Regourd, A C; Raulin, F

1995-01-01

A COSPAR two days Symposium has been dedicated to "Prebiotic chemistry in Space" at the COSPAR Plenary Meeting, (Hamburg, Germany, July 1994). This Symposium was jointly organized by Commissions B (Space studies of the Earth-Moon system, planets and small bodies of the solar system) and F (Life sciences as related to space). Its goal was to review, from an interdisciplinary approach, our knowledge on organic and prebiotic chemistry in small bodies of the Solar System, and on low temperature chemistry and exobiology. The Symposium was sponsored by COSPAR and the IAU (session 1), ESA, NASA, and ISSOL (session 2).

Phototropism in Arabidopsis roots is mediated by two sensory systems.

PubMed

Kiss, J Z; Ruppel, N J; Hangarter, R P

2001-01-01

Phototropism has been well-characterized in stems and stem-like organs, but there have been relatively few studies of root phototropism. Our experiments suggest that there are two photosensory systems that elicit phototropic responses in roots of Arabidopsis thaliana: a previously identified blue-light photoreceptor system mediated by phototropin (=NPH1 protein) and a novel red-light-based mechanism. The phototropic responses in roots are much weaker than the graviresponse, which competes with and often masks the phototropic response. It was through the use of mutant plants with a weakened graviresponse that we were able to identify the activity of the red-light-dependent phototropic system. In addition, the red-light-based photoresponse in roots is even weaker compared to the blue-light response. Our results also suggest that phytochrome may be involved in mediating positive phototropism in roots. c 2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Simultaneous measurement of multiple radiation-induced protein expression profiles using the Luminex(TM) system

NASA Technical Reports Server (NTRS)

Desai, N.; Wu, H.; George, K.; Gonda, S. R.; Cucinotta, F. A.; Cucniotta, F. A. (Principal Investigator)

2004-01-01

Space flight results in the exposure of astronauts to a mixed field of radiation composed of energetic particles of varying energies, and biological indicators of space radiation exposure provides a better understanding of the associated long-term health risks. Current methods of biodosimetry have employed the use of cytogenetic analysis for biodosimetry, and more recently the advent of technological progression has led to advanced research in the use of genomic and proteomic expression profiling to simultaneously assess biomarkers of radiation exposure. We describe here the technical advantages of the Luminex(TM) 100 system relative to traditional methods and its potential as a tool to simultaneously profile multiple proteins induced by ionizing radiation. The development of such a bioassay would provide more relevant post-translational dynamics of stress response and will impart important implications in the advancement of space and other radiation contact monitoring. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Operation of magnetically assisted fluidized beds in microgravity and variable gravity: experiment and theory

NASA Technical Reports Server (NTRS)

Sornchamni, T.; Jovanovic, G. N.; Reed, B. P.; Atwater, J. E.; Akse, J. R.; Wheeler, R. R.

2004-01-01

The conversion of solid waste into useful resources in support of long duration manned missions in space presents serious technological challenges. Several technologies, including supercritical water oxidation, microwave powered combustion and fluidized bed incineration, have been tested for the conversion of solid waste. However, none of these technologies are compatible with microgravity or hypogravity operating conditions. In this paper, we present the gradient magnetically assisted fluidized bed (G-MAFB) as a promising operating platform for fluidized bed operations in the space environment. Our experimental and theoretical work has resulted in both the development of a theoretical model based on fundamental principles for the design of the G-MAFB, and also the practical implementation of the G-MAFB in the filtration and destruction of solid biomass waste particles from liquid streams. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Intracellular magnetophoresis of statoliths in Chara rhizoids and analysis of cytoplasm viscoelasticity.

PubMed

Kuznetsov, O A; Hasenstein, K H

2001-01-01

The statoliths in Chara rhizoids are denser and more diamagnetic than the cytoplasm, therefore they can be displaced inside a living cell by a sufficiently strong high gradient magnetic field (HGMF). An experimental setup for intracellular magnetophoresis of statoliths was developed. The movement of statoliths and rhizoid growth was measured by video microscopy either under the influence of gravity or a HGMF equivalent to about 2 g. The contribution of the cytoskeleton to statolith motility was assayed before and after depolymerizing microtubules with oryzalin and F-actin with latrunculin B. Application of latrunculin caused immediate cessation of growth, clumping of statoliths, and application of HGMF resulted in higher displacement of statoliths. Oryzalin had no effect on the behavior of statoliths. The data indicate that magnetophoresis is a useful tool to study the gravisensing system and rheology of the Chara rhizoid. c 2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Model implementation for dynamic computation of system cost for advanced life support

NASA Technical Reports Server (NTRS)

Levri, J. A.; Vaccari, D. A.

2004-01-01

Life support system designs for long-duration space missions have a multitude of requirements drivers, such as mission objectives, political considerations, cost, crew wellness, inherent mission attributes, as well as many other influences. Evaluation of requirements satisfaction can be difficult, particularly at an early stage of mission design. Because launch cost is a critical factor and relatively easy to quantify, it is a point of focus in early mission design. The method used to determine launch cost influences the accuracy of the estimate. This paper discusses the appropriateness of dynamic mission simulation in estimating the launch cost of a life support system. This paper also provides an abbreviated example of a dynamic simulation life support model and possible ways in which such a model might be utilized for design improvement. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

COSPAR report to United Nations 2004: satellite dynamics

NASA Technical Reports Server (NTRS)

Willis, Pascal

2004-01-01

The COSPAR Panel on Satellite Dynamics (PSD) is concerned with the determination of the position, velocity and orientation in space of artificial and natural satellites around the Earth or in the outer space. The following report highlighs representative activities of this panel and provides general information on related international aspects.

a New IAA Cosmic Study: Establishing a Radio Observatory on the Moon Farside

NASA Astrophysics Data System (ADS)

Heidmann, J.

2002-01-01

In 1998, the IAA decided to develop a new Cosmic Study following a suggestion by its President, M. Yarymovych, based on work I initiated in 1993. This project is jointly fully supported by G. Haerendel, Vice-President of the IAA and President of the COSPAR. After the Symposium " Protection of Part of a Celestial Body for the Scientific Benefit of Humankind: the Lunar Farside Crater SAHA Proposal", which I organized at the COSPAR 1998 Scientific Assembly, the IAA Space Science Committee endorsed also this study. I assembled a Committee including D. McNally, University of London Observatory, for Radio Protection, B. Reijnen, International Institute of Space Law, for Space Law, G. Genta, Politecnico di Torino, for Astronautics, J.-F. Lestrade, Paris-Meudon Observatory, for Radioastronomy, and C. Maccone, IAA SETI and Interstellar Space Exploration Committees, for Mission Management. We encourage contributions from workers in a wide range of interdisciplinary domains: space lawyers, space engineers, astronomers, policy-makers, economists, educationists, media analysts. I started to invite potential contributors from various sources such as programmes of recent conferences of IAF, IAA, IISL, COSPAR, IAU, NASA, ESA and other space agencies, together with news from journals such as Science, Nature, Space News. The basic philosophy is not to refrain from giving access to persons of different opinions, so that a balance can be presented, aiming at some synthetizing consensus. I shall be the Editor, submitting each paper to two referees and taking advice from the Committee in controversial cases.

Scientific ballooning. Proceedings. PSB Meeting of the COSPAR Panel on Technical Problems Related to Scientific Ballooning which was held during the Thirtieth COSPAR Scientific Assembly, Hamburg (Germany), 11 - 21 Jul 1994.

NASA Astrophysics Data System (ADS)

Riedler, W.; Torkar, K.

1996-05-01

This issue is grouped into sections on materials, design, performance and analysis of balloons, reviews of major national and international balloon programmes, novel instrumentation and systems for scientific ballooning, and selected recent scientific observations.

Planetary protection issues for sample return missions.

PubMed

DeVincenzi, D L; Klein, H P

1989-01-01

Sample return missions from a comet nucleus and the Mars surface are currently under study in the US, USSR, and by ESA. Guidance on Planetary Protection (PP) issues is needed by mission scientists and engineers for incorporation into various elements of mission design studies. Although COSPAR has promulgated international policy on PP for various classes of solar system exploration missions, the applicability of this policy to sample return missions, in particular, remains vague. In this paper, we propose a set of implementing procedures to maintain the scientific integrity of these samples. We also propose that these same procedures will automatically assure that COSPAR-derived PP guidelines are achieved. The recommendations discussed here are the first step toward development of official COSPAR implementation requirements for sample return missions.

A Model of Managerial Effectiveness in Information Security: From Grounded Theory to Empirical Test

DTIC Science & Technology

2005-09-13

to observe employee performance (George, 1996) and encourage policy adherence ( Ariss , 2002) have been studied. While the published academic...for excessive monitoring ( Ariss , 2002). Managers have a key role to play in designing monitoring and enforcement systems that are effective yet not... Ariss , S. S. (2002). Computer Monitoring: Benefits and Pitfalls Facing Management. Information & Management, 39(7), 553-558. Armstrong, C. P

The statistical model of origin and evolution planets of Solar system and planetary satellities

NASA Astrophysics Data System (ADS)

Krot, A.

There are the theories for exploring Solar system formation in accord Titius-Bode's low: electromagnetic theories (Birkeland (1912), Alfven (1942)), gravitational theories (Schmidt (1944), Woolfson (1964), Safronov (1969), Dole (1970)), nebular theories (Weizsaecker (1943), Kuiper (1949), Nakano (1970)) [1]-[3]. In spite of great number of work aimed to exploring formation of the Solar system, however, the mentioned theories were not able to explain all phenomena. In this connection the statistical theory for a cosmological body forming (so-called the spheroidal body model) has been proposed in [4]-[11]. Within the framework of this theory, bodies have fuzzy outlines and are represented by means of spheroidal forms. In the work [6], which is a continuation of the papers [4], [5], it has been investigated a slowly evolving in time process of a gravitational compression of a spheroidal body close to an unstable equilibrium state. In the papers [7],[8]the equation of motion of particles inside the weakly gravitating spheroidal body modeled by means of an ideal liquid has been obtained. Using Schwarzschild's and Kerr's metrics a consistency of the proposed statistical model with the general relativity has been shown in [12]. The proposed theory proceeds from the conception for forming a spheroidal body as a protoplanet from planetary nebula; it permits to derive the form of distribution functions for an immovable and rotating spheroidal body [4]-[6],[10]-[13] as well as their density masses (gravitational potentials and strengths) and also to find the distribution function of specific angular momentum of the rotating uniformly spheroidal body [13],[14]. Using the specific angular momentum distribution function this work considers a gas- dust protoplanetary cloud as a rotating and gravitating spheroidal body. Because the specific angular momenta are averaged during conglomeration process the specific angular momenta for a planets of Solar system is found. As a result a new low for Solar system planetary distances is derived (it generalizes the well-known Schmidt low). The new low gives a very good estimation of real planetary distances in Solar system (the relative error of estimation is 0%; absolute error of estimation is 0,5% besides its maximal value is equal to 5% for Earth and Pluto). This low has been applied also to estimation of Jupiter's satellities distances in this work. References: [1] M.M.Nieto, The Tutius-Bode low of planetary distances: its his-tory and theory. Pergamon: Oxford, New York et., 1972. [2] V.S. Safronov, Evolution of Protoplanetary cloud and the formation of the Earth and planets. 1969, Moscow, Nauka, (in Russian); NASA Tech. Transl. F-677, Washington, D.C. 1972. [3] A.V. Vityazev, G.V. Pechrnikova and V.S.Safronov, The Terrestrial planets: origin and early evolution. 1990. Moscow, Nauka (in Russian) [4] A.M.Krot, Achievement in Modern Radioelectronics (Special issue "Cosmic Radiophysics", Moscow), no.8, pp.66-81, 1996 (in Russian). [5] A.M.Krot, Proc. SPIE's 13th Annual Intern.Symp. "AeroSense", vol.3710, pp.1248-1259, Orlando, Florida, USA, April 5-9, 1999. [6] A.M.Krot, Proc. SPIE's 14th Annual Intern.Symp. "AeroSense", vol.4038, pp.1318-1329, Orlando, Florida, USA, April 24-28, 2000. [7] A.M.Krot, Proc. SPIE's 15th Annual Intern. Symposium "AeroSense", vol.4394, pp.1271-1282, Orlando, Florida, USA, April 16-20, 2001. [8] A.M.Krot, Proc. 53rd Intern. Astronautical Congress: The World Space Congress-2002, Houston, Texas, USA, October 10-19, 2002, Preprint IAC-02-J.P.01. - 11 p. [9] A.M.Krot, Proc. 34th Scientific Assembly of the Committee on Space Research (COSPAR)- The 2nd World Space Congress (WSC- 2002), October 10-19, 2002,Houston, Texas, USA. [10] A.M.Krot, Proc. of EGS- AGU-EUG Joint Assembly, Nice, France, April 6-11, 2003, Geophysical Research Abstracts, vol.5, EAE03-À-05568, 2003. [11] A.M. Krot, Proc. of 54 Intern. Astronautical Congress (IAC), September 29-October 3, 2003, Bremen, Germany, Preprint IAC-03-J.1.08. -11p. [12] A.M.Krot , Proc. of 35th COSPAR Scientific Assembly, Paris, France, July 18-25, 2004, Abstract-Nr. COSPAR 04-A-00162. [13] A.Krot, Proc. EGU- 2nd General Assembly, Vienna, Austria, April 24-29, 2005, Geophysical Research Abstracts, vol.7, EGU05-A-04550, 2005; SRef-ID: 1607-7962/gra/. [14] A.Krot Proc. EGU- General Assembly, Vienna, Austria, April 02- 07, 2006, Geophysical Research Abstracts, vol.8, EGU06-A-00216, 2006; SRef-ID: 1607-7962/gra/. 2

Air Force Cambridge Research Laboratories Report on Research, July 1972 - June 1974

DTIC Science & Technology

1975-05-01

Achievements of ALADDIN II DANDEKAR, B. S. 1973 Ann. Am. Geophys. Union Mtg., Wash., D. C. Determination of theAtomic Oxygen Concentration from the (16-20...Terrestrial Phys./I7th 1973 Ann. Am. Geophys. Union Mtg., Wash., D. C. Plenary Mtg. of COSPAR, Sao Paulo, Brazil (16-20 April 1973) (17June - I July 1974...Interplanetary Burlington, Mass.), HUFFMAN, R. E., and PAULSEN, Magnetic Field as Inferred from Polar Cap Observations D. E. 1973 Ann. Am. Geophys. Union

Farming in space: environmental and biophysical concerns.

PubMed

Monje, O; Stutte, G W; Goins, G D; Porterfield, D M; Bingham, G E

2003-01-01

The colonization of space will depend on our ability to routinely provide for the metabolic needs (oxygen, water, and food) of a crew with minimal re-supply from Earth. On Earth, these functions are facilitated by the cultivation of plant crops, thus it is important to develop plant-based food production systems to sustain the presence of mankind in space. Farming practices on earth have evolved for thousands of years to meet both the demands of an ever-increasing population and the availability of scarce resources, and now these practices must adapt to accommodate the effects of global warming. Similar challenges are expected when earth-based agricultural practices are adapted for space-based agriculture. A key variable in space is gravity; planets (e.g. Mars, 1/3 g) and moons (e.g. Earth's moon, 1/6 g) differ from spacecraft orbiting the Earth (e.g. Space stations) or orbital transfer vehicles that are subject to microgravity. The movement of heat, water vapor, CO2 and O2 between plant surfaces and their environment is also affected by gravity. In microgravity, these processes may also be affected by reduced mass transport and thicker boundary layers around plant organs caused by the absence of buoyancy dependent convective transport. Future space farmers will have to adapt their practices to accommodate microgravity, high and low extremes in ambient temperatures, reduced atmospheric pressures, atmospheres containing high volatile organic carbon contents, and elevated to super-elevated CO2 concentrations. Farming in space must also be carried out within power-, volume-, and mass-limited life support systems and must share resources with manned crews. Improved lighting and sensor technologies will have to be developed and tested for use in space. These developments should also help make crop production in terrestrial controlled environments (plant growth chambers and greenhouses) more efficient and, therefore, make these alternative agricultural systems more economically feasible food production systems. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Farming in space: environmental and biophysical concerns

NASA Technical Reports Server (NTRS)

Monje, O.; Stutte, G. W.; Goins, G. D.; Porterfield, D. M.; Bingham, G. E.

2003-01-01

The colonization of space will depend on our ability to routinely provide for the metabolic needs (oxygen, water, and food) of a crew with minimal re-supply from Earth. On Earth, these functions are facilitated by the cultivation of plant crops, thus it is important to develop plant-based food production systems to sustain the presence of mankind in space. Farming practices on earth have evolved for thousands of years to meet both the demands of an ever-increasing population and the availability of scarce resources, and now these practices must adapt to accommodate the effects of global warming. Similar challenges are expected when earth-based agricultural practices are adapted for space-based agriculture. A key variable in space is gravity; planets (e.g. Mars, 1/3 g) and moons (e.g. Earth's moon, 1/6 g) differ from spacecraft orbiting the Earth (e.g. Space stations) or orbital transfer vehicles that are subject to microgravity. The movement of heat, water vapor, CO2 and O2 between plant surfaces and their environment is also affected by gravity. In microgravity, these processes may also be affected by reduced mass transport and thicker boundary layers around plant organs caused by the absence of buoyancy dependent convective transport. Future space farmers will have to adapt their practices to accommodate microgravity, high and low extremes in ambient temperatures, reduced atmospheric pressures, atmospheres containing high volatile organic carbon contents, and elevated to super-elevated CO2 concentrations. Farming in space must also be carried out within power-, volume-, and mass-limited life support systems and must share resources with manned crews. Improved lighting and sensor technologies will have to be developed and tested for use in space. These developments should also help make crop production in terrestrial controlled environments (plant growth chambers and greenhouses) more efficient and, therefore, make these alternative agricultural systems more economically feasible food production systems. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Microinjection--a tool to study gravitropism.

PubMed

Scherp, P; Hasenstein, K H

2003-01-01

Despite extensive studies on plant gravitropism this phenomenon is still poorly understood. The separation of gravity sensing, signal transduction and response is a common concept but especially the mechanism of gravisensing remains unclear. This paper focuses on microinjection as powerful tool to investigate gravisensing in plants. We describe the microinjection of magnetic beads in rhizoids of the green alga Chara and related subsequent manipulation of the gravisensing system. After injection, an external magnet can control the movement of the magnetic beads. We demonstrate successful injection of magnetic beads into rhizoids and describe a multitude of experiments that can be carried out to investigate gravitropism in Chara rhizoids. In addition to examining mechanical properties, bead microinjection is also useful for probing the function of the cytoskeleton by coating beads with drugs that interfere with the cytoskeleton. The injection of fluorescently labeled beads or probes may reveal the involvement of the cytoskeleton during gravistimulation and response in living cells. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Overview of the Martian radiation environment experiment

NASA Technical Reports Server (NTRS)

Zeitlin, C.; Cleghorn, T.; Cucinotta, F.; Saganti, P.; Andersen, V.; Lee, K.; Pinsky, L.; Atwell, W.; Turner, R.; Badhwar, G.

2004-01-01

Space radiation presents a hazard to astronauts, particularly those journeying outside the protective influence of the geomagnetosphere. Crews on future missions to Mars will be exposed to the harsh radiation environment of deep space during the transit between Earth and Mars. Once on Mars, they will encounter radiation that is only slightly reduced, compared to free space, by the thin Martian atmosphere. NASA is obliged to minimize, where possible, the radiation exposures received by astronauts. Thus, as a precursor to eventual human exploration, it is necessary to measure the Martian radiation environment in detail. The MARIE experiment, aboard the 2001 Mars Odyssey spacecraft, is returning the first data that bear directly on this problem. Here we provide an overview of the experiment, including introductory material on space radiation and radiation dosimetry, a description of the detector, model predictions of the radiation environment at Mars, and preliminary dose-rate data obtained at Mars. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

DNA fragmentation induced by Fe ions in human cells: shielding influence on spatially correlated damage

NASA Technical Reports Server (NTRS)

Antonelli, F.; Belli, M.; Campa, A.; Chatterjee, A.; Dini, V.; Esposito, G.; Rydberg, B.; Simone, G.; Tabocchini, M. A.

2004-01-01

Outside the magnetic field of the Earth, high energy heavy ions constitute a relevant part of the biologically significant dose to astronauts during the very long travels through space. The typical pattern of energy deposition in the matter by heavy ions on the microscopic scale is believed to produce spatially correlated damage in the DNA which is critical for radiobiological effects. We have investigated the influence of a lucite shielding on the initial production of very small DNA fragments in human fibroblasts irradiated with 1 GeV/u iron (Fe) ions. We also used gamma rays as reference radiation. Our results show: (1) a lower effect per incident ion when the shielding is used; (2) an higher DNA Double Strand Breaks (DSB) induction by Fe ions than by gamma rays in the size range 1-23 kbp; (3) a non-random DNA DSB induction by Fe ions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Simulation experiments of the effect of space environment on bacteriophage and DNA thin films

NASA Technical Reports Server (NTRS)

Fekete, A.; Ronto, Gy; Hegedus, M.; Modos, K.; Berces, A.; Kovacs, G.; Lammer, H.; Panitz, C.

2004-01-01

The main goal of PUR experiment (phage and uracil response) is to examine and quantify the effect of specific space conditions on nucleic acid models. To achieve this an improved method was elaborated for the preparation of DNA and bacteriophage thin films. The homogeneity of the films was controlled by UV spectroscopy and microscopy. To provide experimental evidence for the hypothesis that interplanetary transfer of the genetic material is possible, phage T7 and isolated T7 DNA thin films have been exposed to selected space conditions: intense UVC radiation (lambda=254 nm) and high vacuum (10(-4) Pa). The effects of DNA hydration, conformation and packing on UV radiation damage were examined. Characteristic changes in the absorption spectrum, in the electrophoretic pattern of DNA and the decrease of the amount of PCR products have been detected indicating the photodamage of isolated and intraphage DNA. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Experimental concept for examination of biological effects of magnetic field concealed by gravity.

PubMed

Yamashita, M; Tomita-Yokotani, K; Hashimoto, H; Takai, M; Tsushima, M; Nakamura, T

2004-01-01

Space is not only a place to study biological effects of gravity, but also provides unique opportunities to examine other environmental factors, where the biological actions are masked by gravity on the ground. Even the earth's magnetic field is steadily acting on living systems, and is known to influence many biological processes. A systematic survey and assessment of its action are difficult to conduct in the presence of dominant factors, such as gravity. Investigation of responses of biological systems against the combined environment of zero-gravity and zero-magnetic field might establish the baseline for the analysis of biological effects of magnetic factors. We propose, in this paper, an experimental concept in this context, together with a practical approach of the experiments, both in orbit and on the ground, with a thin magnetic shielding film. Plant epicotyl growth was taken as an exemplar index to evaluate technical and scientific feasibility of the proposed system concept. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Microinjection--a tool to study gravitropism

NASA Technical Reports Server (NTRS)

Scherp, P.; Hasenstein, K. H.

2003-01-01

Despite extensive studies on plant gravitropism this phenomenon is still poorly understood. The separation of gravity sensing, signal transduction and response is a common concept but especially the mechanism of gravisensing remains unclear. This paper focuses on microinjection as powerful tool to investigate gravisensing in plants. We describe the microinjection of magnetic beads in rhizoids of the green alga Chara and related subsequent manipulation of the gravisensing system. After injection, an external magnet can control the movement of the magnetic beads. We demonstrate successful injection of magnetic beads into rhizoids and describe a multitude of experiments that can be carried out to investigate gravitropism in Chara rhizoids. In addition to examining mechanical properties, bead microinjection is also useful for probing the function of the cytoskeleton by coating beads with drugs that interfere with the cytoskeleton. The injection of fluorescently labeled beads or probes may reveal the involvement of the cytoskeleton during gravistimulation and response in living cells. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Detection of martian amino acids by chemical derivatization coupled to gas chromatography: in situ and laboratory analysis.

PubMed

Rodier, C; Vandenabeele-Trambouze, O; Sternberg, R; Coscia, D; Coll, P; Szopa, C; Raulin, F; Vidal-Madjar, C; Cabane, M; Israel, G; Grenier-Loustalot, M F; Dobrijevic, M; Despois, D

2001-01-01

If there is, or ever was, life in our solar system beyond the Earth, Mars is the most likely place to search for. Future space missions will have then to take into account the detection of prebiotic molecules or molecules of biological significance such as amino acids. Techniques of analysis used for returned samples have to be very sensitive and avoid any chemical or biological contamination whereas in situ techniques have to be automated, fast and low energy consuming. Several possible methods could be used for in situ amino acid analyses on Mars, but gas chromatography would likely be the most suitable. Returned samples could be analyzed by any method in routine laboratory use such as gas chromatography, already successfully performed for analyses of organic matter including amino acids from martian meteorites. The derivatization step, which volatilizes amino acids to perform both in situ and laboratory analysis by gas chromatography, is discussed here. c2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Population dynamics of transgenic strain Escherichia coli Z905/pPHL7 in freshwater and saline lake water microcosms with differing microbial community structures

NASA Technical Reports Server (NTRS)

Popova, L. Yu; Kargatova, T. V.; Ganusova, E. E.; Lobova, T. I.; Boyandin, A. N.; Mogilnaya, O. A.; Pechurkin, N. S.

2005-01-01

Populations of Escherichia coli Z905/pPHL7, a transgenic microorganism, were heterogenic in the expression of plasmid genes when adapting to the conditions of water microcosms of various mineralization levels and structure of microbial community. This TM has formed two subpopulations (ampicillin-resistant and ampicillin-sensitive) in every microcosm. Irrespective of mineralization level of a microcosm, when E. coli Z905/pPHL7 alone was introduced, the ampicillin-resistant subpopulation prevailed, while introduction of the TM together with indigenous bacteria led to the dominance of the ampicillin-sensitive subpopulation. A high level of lux gene expression maintained longer in the freshwater microcosms than in sterile saline lake water microcosms. A horizontal gene transfer has been revealed between the jointly introduced TM and Micrococcus sp. 9/pSH1 in microcosms with the Lake Shira sterile water. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

Planetary Protection Progress of Hayabusa2 and Its Piggyback PROCYON: Launch, Earth Swingby and Outbound Cruising Phases

NASA Astrophysics Data System (ADS)

Yano, Hajime; Yoshikawa, Makoto; Sarli, Bruno; Ozaki, Naoya; Funase, Ryu; Tsuda, Yuichi; Chujo, Toshihiro; Ariu, Kaito

2016-07-01

Hayabusa-2 is Japan's second asteroid sample return mission which was successfully launched into the planned Earth departure trajectory with the H-IIA rocket on December 3rd, 2014, together with a group of its interplanetary piggyback micro- spacecraft, including the PROCYON(Proximate Object Close flYby with Optical Navigation)spacecraft, the world's first 50 kg-class deep space micro-spacecraft developed by the University of Tokyo and the Japan Aerospace Exploration Agency. The Hayabusa-2 spacecraft will go to Rug, a C-type NEO, and attempt surface investigations with daughter rovers (MINERVA-II series and MASCOT), artificial impact cratering experiment (SCI) and both surface and sub-surface sampling (Sampler) in 2018-2019 and plans to return to the Earth in December 2020. The PROCYON mission objective was to demonstrate a micro-spacecraft bus technology for deep space exploration and proximity flyby to asteroids performing optical measurements. Both of the above missions were fully evaluated by the COSPAR Planetary Protection Panel at the dedicated COSPAR colloquium and scientific assembly in 2014 and the COSPAR PPP has endorsed the Category-2 for their outbound trajectories and the non-restricted Earth return for the inbound trajectory of Hayabusa-2. As a part of the fulfillments of the Category-2 classification, both spacecraft must be compliant with the COSPAR PPP requirements of non-impact probability to Mars since they would have enough energy to reach and beyond the orbit of Mars, due to the Earth swing-by and ion engine operations for their outbound cruising. As for the Hayabusa-2 spacecraft, it successfully performed its Earth gravity assist in December 2015, resulting on accurate orbit determination for the post-swing-by orbit to be ready to restart the ion engine operation. Thus the non-impact probability to Mars did not change from the estimate given by Chujo, et al. (2015). As for the PROCYON spacecraft after the completion of the bus system demonstration, it started deep space maneuver using the ion engines so that the spacecraft would be injected into an asteroid flyby trajectory via the Earth swing-by scheduled in December 2015. However, malfunction of the PROCYON high voltage system in the thruster occurred in March 2015, and the operation of the ion thruster stopped after 223 hours of successful continuous operation. Due to this anomaly, PROCYON gave up reaching its final destination (NEO "2000 DP107"); thus it now can be said that the spacecraft will never impact on Mars. In this paper, we summarize the mission status of the both projects in terms of the COSPAR PPP perspectives.

Superposed Epoch Analysis of Ring Current Geoeffectiveness Related to Solar Wind and Plasma Sheet Drivers

NASA Technical Reports Server (NTRS)

Liemohm, M. W.; Kozyra, J. U.; Thomsen, M. F.; Borovsky, J. E.; Gahurthakurta, Madulika (Technical Monitor)

2004-01-01

The goal of that proposal was to examine the relationship between solar wind drivers and ring current dynamics through data analysis and numerical simulations. The data analysis study was a statistical examination (via superposed epoch analyses) of a solar cycle's worth of storm data. Solar wind data, geophysical indices, and geosynchronous plasma data were collected for every time period with Dst< -50 nT from 1989 through 2002, and the storm list now exceeds 400 entries. This work was first conducted by a summer undergraduate student, Mr. John Vann (University of Kansas), with funding from the NSF Research Experience for Undergraduates program. It was then continued by a University of Michigan graduate student, Mr. Jichun Zhang. Mr. Zhang is now in his fourth year at U-M and is progressing very well toward a PhD in space science. His dissertation will be based on his data analysis and modeling efforts using this geomagnetic storm database. The results of the data analysis study have been the focus of several conference presentations, and the first manuscript has just been published. Two additional papers are presently being prepared, one on average (superposed) solar wind features for various storm subsets (e.g., intense storms at solar maximum), and another on geosynchronous plasma features for these same storm subsets. The latter result was highlighted by the TR&T program director in his presentation at the COSPAR meeting this summer.

Principal components analysis of Jupiter VIMS spectra

USGS Publications Warehouse

Bellucci, G.; Formisano, V.; D'Aversa, E.; Brown, R.H.; Baines, K.H.; Bibring, J.-P.; Buratti, B.J.; Capaccioni, F.; Cerroni, P.; Clark, R.N.; Coradini, A.; Cruikshank, D.P.; Drossart, P.; Jaumann, R.; Langevin, Y.; Matson, D.L.; McCord, T.B.; Mennella, V.; Nelson, R.M.; Nicholson, P.D.; Sicardy, B.; Sotin, Christophe; Chamberlain, M.C.; Hansen, G.; Hibbits, K.; Showalter, M.; Filacchione, G.

2004-01-01

During Cassini - Jupiter flyby occurred in December 2000, Visual-Infrared mapping spectrometer (VIMS) instrument took several image cubes of Jupiter at different phase angles and distances. We have analysed the spectral images acquired by the VIMS visual channel by means of a principal component analysis technique (PCA). The original data set consists of 96 spectral images in the 0.35-1.05 ??m wavelength range. The product of the analysis are new PC bands, which contain all the spectral variance of the original data. These new components have been used to produce a map of Jupiter made of seven coherent spectral classes. The map confirms previously published work done on the Great Red Spot by using NIMS data. Some other new findings, presently under investigation, are presented. ?? 2004 Published by Elsevier Ltd on behalf of COSPAR.

Protecting the Moon for research: ILEWG report

NASA Astrophysics Data System (ADS)

Foing, Bernard H.

We give a report on recommendations with emphasis on environment protection, and since last COSPAR from ILEWG International conferences Exploration and Utilisation of the Moon on held at Cape Canaveral in 2008 (ICEUM10), and in Beijing in May 2010 with IAF (GLUC -ICEUM11). We discuss the different rationale for Moon exploration, as debated at ILEWG. ILEWG Science task group has listed priorities for scientific investigations: clues on the formation and evolution of rocky planets, accretion and bombardment in the inner solar system, comparative planetology processes (tectonic, volcanic, impact cratering, volatile delivery), records astrobiology, survival of organics; past, present and future life; sciences from a biology lunar laboratory. We discuss how to preserve Moon research potential in these areas while operating with instruments, landers, rover during a cooperative robotic village, and during the transition form lunar human outpost to permanent sustainable human base. We discuss how Moon-Mars Exploration can inspire solutions to global Earth sustained development with the trade-off of In-Situ Utilisation of resources; Establishment of permanent robotic infrastructures, Environmental and planetary protection aspects and lessons for Mars; Life sciences laboratories, and support to human exploration. Co-authors: ILEWG Task Groups on Science, Technology and Human Lunar Bases ILEWG Reference documents: http://sci.esa.int/ilewg -10th ILEWG Conference on Exploration and Utilisation of the Moon, NASA Lunar Ex-ploration Analysis Group-PSace Resources Roundtable, Cape Canaveral October 2008, pro-gramme online at http://sci.esa.int/ilewg/ -9th ILEWG Conference on Exploration and Utilisation of the Moon, ICEUM9 Sorrento 2007, programme online at http://sci.esa.int/ilewg/ -8th ILEWG Conference on Exploration and Utilisation of the Moon, Beijing July 2006, programme online at http://sci.esa.int/ilewg/ -The Moon and Near Earth Objects (P. Ehrenfreund , B.H. Foing, A. Cellino Editors), Ad-vances in Space Research, Volume 37, Issue 1, pp 1-192, 2006 -7th ILEWG Conference on Exploration and Utilisation of the Moon, Toronto Sept 2005, Programme and Proceedings on line at www.ilewg.org, R. Richards et al Editors -6th ILEWG Conference on Exploration and Utilisation of the Moon, Udaipur Nov. 2004, Proceedings ( N. Bhandari Editor), Journal Earth System Science, India, 114, No6, Dec 2005, pp. 573-841 -5th ILEWG Conference on Exploration and Utilisation of the Moon, Hawaii Nov 2003, Pro-ceedings ILC2005/ICEUM5 (S.M. Durst et al Editors), Vol 108, 1-576 pp, Science and Tech-nology Series, American Astronautical Society, 2004 -'The next steps in exploring deep space -A cosmic study by the IAA', W. Huntress, D. Stetson, R. Farquhar, J. Zimmerman, B. Clark, W. O'Neil, R. Bourke and B. Foing, Acta Astronautica, Vol 58, Issues 6-7, March-April 2006, p302-377 -IAA/ESA workshop on "Next Steps in Exploring Deep Space", ESTEC 22-23 sept. 2003 (B.H. Foing W. Huntress, conveners) Lunar Exploration, Planetary and Space Science, Vol 50, issue 14-15, Dec 2002 (B.H. Foing al) -ESLAB36 symposium on "Earth-like Planets and Moons", 2002, ESA-SP514, pp. 1-356, (B.H.Foing B. Battrick, editors) -'Lunar Exploration 2000', (B.H. Foing, D. Heather, Editors), Adv. Space Research Vol 30, Nr 8, 2002 -'Earth-Moon Relationships', Proceedings of the Conference held in Padova, Italy at the Ac-cademia Galileiana di Scienze Lettere ed Arti, Nov. 2000, (C. Barbieri and F. Rampazzi, Editors), in Earth, Moon , Planets Vol. 85-86, Nos 1-3, pp 1-575, 2001 -4th International Conference on Exploration and Utilisation of the Moon, ESTEC, 2000, ESA SP-462 (B.H. Foing M. Perry, editors) -Investing in Space: The Challenge for Europe. Long-Term Space Policy Committee, Second Report, May 1999. ESA-SP-2000 -2nd International Lunar Workshop, held at Kyoto in October 1996, Proceedings, H. Mizutani, editor, Japan Space Forum Publisher, 1997 International Lunar Workshop, 1994 May 31-June 3, Beatenberg, Switzerland. Proceedings. Ed. Balsiger, H. et al. European Space Agency, 1994. ESA-SP-1170 -Astronomy and Space Science from the Moon', Proceedings of COSPAR/IAF session at World Congress, Washington, (B.H. Foing et al editors), Advances in Space Research, Volume 14, Issue 6, 1994 -Mission to the Moon, Europe's Priorities for Scientific Exploration and Utilisation of the Moon', R.M. Bonnet et al, European Space Agency, ESA SP-1150, June 1992

Hematopoietic responses under protracted exposures to low daily dose gamma irradiation.

PubMed

Seed, T M; Fritz, T E; Tolle, D V; Jackson, W E

2002-01-01

In attempting to evaluate the possible health consequences of chronic ionizing radiation exposure during extended space travel (e.g., Mars Mission), ground-based experimental studies of the clinical and pathological responses of canines under low daily doses of 60Co gamma irradiation (0.3-26.3 cGy d-1) have been examined. Specific reference was given to responses of the blood forming system. Results suggest that the daily dose rate of 7.5 cGy d-1 represents a threshold below which the hematopoietic system can retain either partial or full trilineal cell-producing capacity (erythropoiesis, myelopoiesis, and megakaryopoiesis) for extended periods of exposure (>1 yr). Trilineal capacity was fully retained for several years of exposure at the lowest dose-rate tested (0.3 cGy d-1) but was completely lost within several hundred days at the highest dose-rate (26.3 cGy d-1). Retention of hematopoietic capacity under chronic exposure has been demonstrated to be mediated by hematopoietic progenitors with acquired radioresistance and repair functions, altered cytogenetics, and cell-cycle characteristics. Radiological, biological, and temporal parameters responsible for these vital acquisitions by hematopoietic progenitors have been partially characterized. These parameters, along with threshold responses, are described and discussed in relation to potential health risks of the space traveler under chronic stress of low-dose irradiation. Published by Elsevier Science Ltd on behalf of COSPAR.

Life sciences and space research X. Proceedings of the open meeting of working group 5 of the fourteenth plenary meeting of COSPAR, Seattle, Washington, June 21--July 2, 1971

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vishniac, W.

1972-01-01

From 14th COSPAR meeting on life sciences and space research X; Seattle, Washington, USA (17 Jun 1971). Separate asbstracts were prepared for 7 of the 27 papers appearing in these proceedings. The other papers discuss topics in the following general areas: planetary quarantine; effects of weightlessness, effects of space on living matter; and preparations for the exploration of Mars. (ERB)

Life sciences and space research 24 (4): Planetary biology and origins of life; Topical Meeting of the COSPAR Interdisciplinary Scientific Commission F (Meeting F3) of the COSPAR Plenary Meeting, 29th, Washington, DC, Aug. 28-Sep. 5, 1992

NASA Technical Reports Server (NTRS)

Greenberg, J. M. (Editor); Oro, J. (Editor); Brack, A. (Editor); Devincenzi, D. L. (Editor); Banin, A. (Editor); Friedmann, E. I. (Editor); Rummel, J. D. (Editor); Raulin, F. (Editor); Mckay, C. P. (Editor); Baltscheffsky, H. (Editor)

1995-01-01

The proceedings include sessions on extraterrestrial organic chemistry and the origins of life; life on Mars: past, present and future; planetary protection of Mars missions; chemical evolution on Titan; origins and early evolution of biological (a) energy transduction and membranes (b) information and catalysis; and carbon chemistry and isotopic fractionations in astrophysical environments.

Soil and crop management experiments in the Laboratory Biosphere: an analogue system for the Mars on Earth(R) facility.

PubMed

Silverstone, S; Nelson, M; Alling, A; Allen, J P

2005-01-01

During the years 2002 and 2003, three closed system experiments were carried out in the "Laboratory Biosphere" facility located in Santa Fe, New Mexico. The program involved experimentation of "Hoyt" Soy Beans, (experiment #1) USU Apogee Wheat (experiment #2) and TU-82-155 sweet potato (experiment #3) using a 5.37 m2 soil planting bed which was 30 cm deep. The soil texture, 40% clay, 31% sand and 28% silt (a clay loam), was collected from an organic farm in New Mexico to avoid chemical residues. Soil management practices involved minimal tillage, mulching, returning crop residues to the soil after each experiment and increasing soil biota by introducing worms, soil bacteria and mycorrhizae fungi. High soil pH of the original soil appeared to be a factor affecting the first two experiments. Hence, between experiments #2 and #3, the top 15 cm of the soil was amended using a mix of peat moss, green sand, humates and pumice to improve soil texture, lower soil pH and increase nutrient availability. This resulted in lowering the initial pH of 8.0-6.7 at the start of experiment #3. At the end of the experiment, the pH was 7.6. Soil nitrogen and phosphorus has been adequate, but some chlorosis was evident in the first two experiments. Aphid infestation was the only crop pest problem during the three experiments and was handled using an introduction of Hyppodamia convergens. Experimentation showed there were environmental differences even in this 1200 cubic foot ecological system facility, such as temperature and humidity gradients because of ventilation and airflow patterns which resulted in consequent variations in plant growth and yield. Additional humidifiers were added to counteract low humidity and helped optimize conditions for the sweet potato experiment. The experience and information gained from these experiments are being applied to the future design of the Mars On Earth(R) facility (Silverstone et al., Development and research program for a soil-based bioregenerative agriculture system to feed a four person crew at a Mars base, Advances in Space Research 31(1) (2003) 69-75; Allen and Alling, The design approach for Mars On Earth(R), a biospheric closed system testing facility for long-term space habitation, American Institute of Aeronautics and Astronautics Inc., IAC-02-IAA.8.2.02, 2002). c2005 Published by Elsevier Ltd on behalf of COSPAR.

Report from International Lunar Exploration Working Group (ILEWG) to COSPAR

NASA Astrophysics Data System (ADS)

Foing, Bernard H.

We refer to COSPAR and ILEWG ICEUM and lunar conferences and declarations [1-18]. We discuss how lunar missions SMART-1, Kaguya, Chang'E1&2, Chandrayaan-1, LCROSS, LRO, GRAIL, LADEE, Chang'E3 and upcoming missions contribute to lunar exploration objectives & roadmap. We present the GLUC/ICEUM11 declaration and give a report on ongoing relevant ILEWG community activities, with focus on: “1. Science and exploration - World-wide access to raw and derived (geophysical units) data products using consistent formats and coordinate systems will maximize return on investment. We call to develop and implement plans for generation, validation, and release of these data products. Data should be made available for scientific analysis and supporting the development and planning of future missions - There are still Outstanding Questions: Structure and composition of crust, mantle, and core and implications for the origin and evolution of the Earth-Moon system; Timing, origin, and consequences of late heavy bombardment; Impact processes and regolith evolution; Nature and origin of volatile emplacement; Implications for resource utilization. These questions require international cooperation and sharing of results in order to be answered in a cost-effective manner - Ground truth information on the lunar far side is missing and needed to address many important scientific questions, e.g. with a sample return from South Pole-Aitken Basin - Knowledge of the interior is poor relative to the surface, and is needed to address a number of key questions, e.g. with International Lunar Network for seismometry and other geophysical measurements - Lunar missions will be driven by exploration, resource utilization, and science; we should consider minimum science payload for every mission, e.g., landers and rovers should carry instruments to determine surface composition and mineralogy - It is felt important to have a shared database about previous missions available for free, so as to provide inputs to future missions, including a gap analysis of needed measurements. Highly resolved global data sets are required. Autonomous landing and hazard avoidance will depend on the best topographic map of the Moon, achievable by combining shared data. - New topics such as life sciences, partial gravity processes on the Moon should be followed in relation to future exploration needs.” http://sci.esa.int/ilewg/ http://sci.esa.int/ilewg/47170-gluc-iceum11-beijing-2010lunar-declaration/ References: [1] 1st International Lunar Workshop, Balsiger H. et al., Editors, European Space Agency, 1994. ESA-SP-1170. [2] 2nd International Lunar Workshop, Kyoto, H. Mizutani, editor, Japan Space Forum Publisher, 1997. [3] 3rd International Lunar Workshop, Moscow 1998, E. Galimov, editor. [4] ICEUM4, ESTEC, 2000, ESA SP-462, B.H. Foing & M. Perry, editors. [5] ICEUM5, Hawaii Nov 2003, Durst S.M. et al, Editors, Vol 108, 1-576 pp, Science and Technology Series, American Astronautical Society, 2004. [6] ICEUM6, Udaipur 2004, Bhandari N., Editor, Journal Earth Sys-tem Science, India, 114, No6, Dec 2005, pp. 573-841. [7] ICEUM7, Toronto Sept 2005, sci.esa.int/ilewg. [8] ICEUM8, Beijing July 2006, Journal of Chinese Society of Astronautics, Vol. 28 Sup., 2007, Ji W., Editor. [9] ICEUM9, Sorrento, Italy, Foing B., Espinasse S., Kosters G., Editors. http://sci.esa.int/iceum9, Dec. 2007), [11] Ehrenfreund, P., Foing, B.H., Cellino, A. Editors, The Moon and Near Earth Objects, ASR Vol 37, 1, 2006. [12] Foing, B.H. et al editors, 'Astronomy and Space Science from the Moon', ASR 14, 6, 1994. [13] Ip W.-H., Foing, B.H., Masson Ph.L., editors, The Moon and Mars, ASR Vol 23, 11, 1999. [14] Foing, B.H. et al, editor, Lunar Exploration, Planetary and Space Science, Vol 50, 14-15, 2002. [15] Foing, B.H., Heather, D. editors, 'Lunar Exploration 2000', ASR Vol 30, Nr 8, 2002. [16] Huntress, W. et al 'The next steps in exploring deep space - A cosmic study by the IAA', Acta Astronautica, Vol 58, Issues 6-7, 2006, p302-377. [17] http://sci.esa.int/ilewg/43654-declaration-iceum10-leag-srr-florida-2008/ [18] Ehrenfreund P. et al (COSPAR planetary exploration panel report) 2012, ASR Vol 49, Nr 1, pp. 2-48.

Towards a Global Hub and a Network for Collaborative Advancing of Space Weather Predictive Capabilities.

NASA Astrophysics Data System (ADS)

Kuznetsova, M. M.; Heynderickz, D.; Grande, M.; Opgenoorth, H. J.

2017-12-01

The COSPAR/ILWS roadmap on space weather published in 2015 (Advances in Space Research, 2015: DOI: 10.1016/j.asr.2015.03.023) prioritizes steps to be taken to advance understanding of space environment phenomena and to improve space weather forecasting capabilities. General recommendations include development of a comprehensive space environment specification, assessment of the state of the field on a 5-yr basis, standardization of meta-data and product metrics. To facilitate progress towards roadmap goals there is a need for a global hub for collaborative space weather capabilities assessment and development that brings together research, engineering, operational, educational, and end-user communities. The COSPAR Panel on Space Weather is aiming to build upon past progress and to facilitate coordination of established and new international space weather research and development initiatives. Keys to the success include creating flexible, collaborative, inclusive environment and engaging motivated groups and individuals committed to active participation in international multi-disciplinary teams focused on topics addressing emerging needs and challenges in the rapidly growing field of space weather. Near term focus includes comprehensive assessment of the state of the field and establishing an internationally recognized process to quantify and track progress over time, development of a global network of distributed web-based resources and interconnected interactive services required for space weather research, analysis, forecasting and education.

Planetary Protection Technologies: Technical Challenges for Mars Exploration

NASA Technical Reports Server (NTRS)

Buxbaum, Karen L.

2005-01-01

The search for life in the solar system, using either in situ analysis or sample return, brings with it special technical challenges in the area of planetary protection. Planetary protection (PP) requires planetary explorers to preserve biological and organic conditions for future exploration and to protect the Earth from potential extraterrestrial contamination that could occur as a result of sample return to the Earth-Moon system. In view of the exploration plans before us, the NASA Solar System Exploration Program Roadmap published in May 2003 identified planetary protection as one of 13 technologies for "high priority technology investments." Recent discoveries at Mars and Jupiter, coupled with new policies, have made this planning for planetary protection technology particularly challenging and relevant.New missions to Mars have been formulated, which present significantly greater forward contamination potential. New policies, including the introduction by COSPAR of a Category IVc for planetary protection, have been adopted by COSPAR in response. Some missions may not be feasible without the introduction of new planetary protection technologies. Other missions may be technically possible but planetary protection requirements may be so costly to implement with current technology that they are not affordable. A strategic investment strategy will be needed to focus on technology investments designed to enable future missions and reduce the costs of future missions. This presentation will describe some of the potential technological pathways that may be most protective.

Material balance and diet in bioregenerative life support systems: connection with coefficient of closure.

PubMed

Manukovsky, N S; Kovalev, V S; Somova, L A; Gurevich, Yu L; Sadovsky, M G

2005-01-01

Bioregenerative life support systems (BLSS) with different coefficients of closure are considered. The 66.2% coefficient of closure achieved in "BIOS-3" facility experiments has been taken as a base value. The increase in coefficient of closure up to 72.6-93.0% is planned due to use of soil-like substrate (SLS) and concentrating of urine. Food values were estimated both in a base variant ("BIOS-3"), and with increases in the coefficient of closure. It is shown that food requirements will be more fully satisfied by internal crop production with an increase in the coefficient of closure of the BLSS. Changes of massflow rates on an 'input-output' and inside BLSS are considered. Equations of synthesis and degradation of organic substances in BLSS were examined using a stoichiometric model. The paper shows that at incomplete closure of BLSS containing SLS there is a problem of nitrogen balancing. To compensate for the removal of nitrogen from the system in urine and feces, it is necessary to introduce food and a nitrogen-containing additive. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

Phytochromes play a role in phototropism and gravitropism in Arabidopsis roots.

PubMed

Correll, Melanie J; Coveney, Katrina M; Raines, Steven V; Mullen, Jack L; Hangarter, Roger P; Kiss, John Z

2003-01-01

Phototropism as well as gravitropism plays a role in the oriented growth of roots in flowering plants. In blue or white light, roots exhibit negative phototropism, but red light induces positive phototropism in Arabidopsis roots. Phytochrome A (phyA) and phyB mediate the positive red-light-based photoresponse in roots since single mutants (and the double phyAB mutant) were severely impaired in this response. In blue-light-based negative phototropism, phyA and phyAB (but not phyB) were inhibited in the response relative to the WT. In root gravitropism, phyB and phyAB (but not phyA) were inhibited in the response compared to the WT. The differences observed in tropistic responses were not due to growth limitations since the growth rates among all the mutants tested were not significantly different from that of the WT. Thus, our study shows that the blue-light and red-light systems interact in roots and that phytochrome plays a key role in plant development by integrating multiple environmental stimuli. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Adaptive response studies may help choose astronauts for long-term space travel.

PubMed

Mortazavi, S M; Cameron, J R; Niroomand-rad, A

2003-01-01

Long-term manned exploratory missions are planned for the future. Exposure to high-energy neutrons, protons and high charge and energy particles during a deep space mission, needs protection against the detrimental effects of space radiation. It has been suggested that exposure to unpredictable extremely large solar particle events would kill the astronauts without massive shielding. To reduce this risk to astronauts and to minimize the need for shielding, astronauts with highest significant adaptive responses should be chosen. It has been demonstrated that some humans living in very high natural radiation areas have acquired high adaptive responses to external radiation. Therefore, we suggest that for a deep space mission the adaptive response of all potential crew members be measured and only those with high adaptive response be chosen. We also proclaim that chronic exposure to elevated levels of radiation can considerably decrease radiation susceptibility and better protect astronauts against the unpredictable exposure to sudden and dramatic increase in flux due to solar flares and coronal mass ejections. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

An improved Green's function for ion beam transport

NASA Technical Reports Server (NTRS)

Tweed, J.; Wilson, J. W.; Tripathi, R. K.

2004-01-01

Ion beam transport theory allows testing of material transmission properties in the laboratory environment generated by particle accelerators. This is a necessary step in materials development and evaluation for space use. The approximations used in solving the Boltzmann transport equation for the space setting are often not sufficient for laboratory work and those issues are the main emphasis of the present work. In consequence, an analytic solution of the linear Boltzmann equation is pursued in the form of a Green's function allowing flexibility in application to a broad range of boundary value problems. It has been established that simple solutions can be found for high charge and energy (HZE) ions by ignoring nuclear energy downshifts and dispersion. Such solutions were found to be supported by experimental evidence with HZE ion beams when multiple scattering was added. Lacking from the prior solutions were range and energy straggling and energy downshift with dispersion associated with nuclear events. Recently, we have found global solutions including these effects providing a broader class of HZE ion solutions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Magnetic levitation-based Martian and Lunar gravity simulator

NASA Technical Reports Server (NTRS)

Valles, J. M. Jr; Maris, H. J.; Seidel, G. M.; Tang, J.; Yao, W.

2005-01-01

Missions to Mars will subject living specimens to a range of low gravity environments. Deleterious biological effects of prolonged exposure to Martian gravity (0.38 g), Lunar gravity (0.17 g), and microgravity are expected, but the mechanisms involved and potential for remedies are unknown. We are proposing the development of a facility that provides a simulated Martian and Lunar gravity environment for experiments on biological systems in a well controlled laboratory setting. The magnetic adjustable gravity simulator will employ intense, inhomogeneous magnetic fields to exert magnetic body forces on a specimen that oppose the body force of gravity. By adjusting the magnetic field, it is possible to continuously adjust the total body force acting on a specimen. The simulator system considered consists of a superconducting solenoid with a room temperature bore sufficiently large to accommodate small whole organisms, cell cultures, and gravity sensitive bio-molecular solutions. It will have good optical access so that the organisms can be viewed in situ. This facility will be valuable for experimental observations and public demonstrations of systems in simulated reduced gravity. c2005 Published by Elsevier Ltd on behalf of COSPAR.

Phytochromes play a role in phototropism and gravitropism in Arabidopsis roots

NASA Technical Reports Server (NTRS)

Correll, Melanie J.; Coveney, Katrina M.; Raines, Steven V.; Mullen, Jack L.; Hangarter, Roger P.; Kiss, John Z.

2003-01-01

Phototropism as well as gravitropism plays a role in the oriented growth of roots in flowering plants. In blue or white light, roots exhibit negative phototropism, but red light induces positive phototropism in Arabidopsis roots. Phytochrome A (phyA) and phyB mediate the positive red-light-based photoresponse in roots since single mutants (and the double phyAB mutant) were severely impaired in this response. In blue-light-based negative phototropism, phyA and phyAB (but not phyB) were inhibited in the response relative to the WT. In root gravitropism, phyB and phyAB (but not phyA) were inhibited in the response compared to the WT. The differences observed in tropistic responses were not due to growth limitations since the growth rates among all the mutants tested were not significantly different from that of the WT. Thus, our study shows that the blue-light and red-light systems interact in roots and that phytochrome plays a key role in plant development by integrating multiple environmental stimuli. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Evaluating and optimizing horticultural regimes in space plant growth facilities

NASA Technical Reports Server (NTRS)

Berkovich, Y. A.; Chetirkin, P. V.; Wheeler, R. M.; Sager, J. C.

2004-01-01

In designing innovative space plant growth facilities (SPGF) for long duration space flight, various limitations must be addressed including onboard resources: volume, energy consumption, heat transfer and crew labor expenditure. The required accuracy in evaluating on board resources by using the equivalent mass methodology and applying it to the design of such facilities is not precise. This is due to the uncertainty of the structure and not completely understanding the properties of all associated hardware, including the technology in these systems. We present a simple criteria of optimization for horticultural regimes in SPGF: Qmax = max [M x (EBI)2/(V x E x T], where M is the crop harvest in terms of total dry biomass in the plant growth system; EBI is the edible biomass index (harvest index), V is volume occupied by the crop; E is the crop light energy supply during growth; T is the crop growth duration. The criterion reflects directly on the consumption of onboard resources for crop production. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Seed-to-seed growth of Arabidopsis thaliana on the International Space Station

NASA Technical Reports Server (NTRS)

Link, B. M.; Durst, S. J.; Zhou, W.; Stankovic, B.

2003-01-01

The assembly of the International Space Station (ISS) as a permanent experimental outpost has provided the opportunity for quality plant research in space. To take advantage of this orbital laboratory, engineers and scientists at the Wisconsin Center for Space Automation and Robotics (WCSAR), University of Wisconsin-Madison, developed a plant growth facility capable of supporting plant growth in the microgravity environment. Utilizing this Advanced Astroculture (ADVASC) plant growth facility, an experiment was conducted with the objective to grow Arabidopsis thaliana plants from seed-to-seed on the ISS. Dry Arabidopsis seeds were anchored in the root tray of the ADVASC growth chamber. These seeds were successfully germinated from May 10 until the end of June 2001. Arabidopsis plants grew and completed a full life cycle in microgravity. This experiment demonstrated that ADVASC is capable of providing environment conditions suitable for plant growth and development in microgravity. The normal progression through the life cycle, as well as the postflight morphometric analyses, demonstrate that Arabidopsis thaliana does not require the presence of gravity for growth and development. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Planetarium Inversum -- a space vision for Earth education.

PubMed

Lotsch, B

2003-01-01

In a planetarium, the visitor is sitting on Earth and looking into an imaginary space. The Planetarium Inversum is the opposite: visitors are sitting in a space station, looking down on Mother Earth. It is a scientifically-based information show with visitors involvement, its elements being partially virtual (Earth in space has to be projected with highest possible resolution) but also containing real structures, such as the visitors' Earth observatory with adjacent biological systems (plant cultures and other ecological life support components). Its main message concerns the limits and the vulnerability of our home planet, its uniqueness, beauty and above all, its irreplaceableness: Earth does not have an emergency exit. The Earth observatory is part of a ring shaped, rotating space station of the type designed by Wernher von Braun decades ago. Visitors are told that gravity is being substituted by centrifugal force. Both types of life support systems are being demonstrated--self regenerative life based ones and technical ones as a backup (solar electric splitting of water and chemical absorption of respiratory CO2). c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Magnetic levitation-based Martian and Lunar gravity simulator.

PubMed

Valles, J M; Maris, H J; Seidel, G M; Tang, J; Yao, W

2005-01-01

Missions to Mars will subject living specimens to a range of low gravity environments. Deleterious biological effects of prolonged exposure to Martian gravity (0.38 g), Lunar gravity (0.17 g), and microgravity are expected, but the mechanisms involved and potential for remedies are unknown. We are proposing the development of a facility that provides a simulated Martian and Lunar gravity environment for experiments on biological systems in a well controlled laboratory setting. The magnetic adjustable gravity simulator will employ intense, inhomogeneous magnetic fields to exert magnetic body forces on a specimen that oppose the body force of gravity. By adjusting the magnetic field, it is possible to continuously adjust the total body force acting on a specimen. The simulator system considered consists of a superconducting solenoid with a room temperature bore sufficiently large to accommodate small whole organisms, cell cultures, and gravity sensitive bio-molecular solutions. It will have good optical access so that the organisms can be viewed in situ. This facility will be valuable for experimental observations and public demonstrations of systems in simulated reduced gravity. c2005 Published by Elsevier Ltd on behalf of COSPAR.

Effects of temperature, CO2/O2 concentrations and light intensity on cellular multiplication of microalgae, Euglena gracilis

NASA Technical Reports Server (NTRS)

Kitaya, Y.; Azuma, H.; Kiyota, M.

2005-01-01

Microalgae culture is likely to play an important role in aquatic food production modules in bioregenerative systems for producing feeds for fish, converting CO2 to O2 and remedying water quality as well as aquatic higher plants. In the present study, the effects of culture conditions on the cellular multiplication of microalgae, Euglena gracilis, was investigated as a fundamental study to determine the optimum culture conditions for microalgae production in aquatic food production modules including both microalgae culture and fish culture systems. E. gracilis was cultured under conditions with five levels of temperatures (25-33 degrees C), three levels of CO2 concentrations (2-6%), five levels of O2 concentrations (10-30%), and six levels of photosynthetic photon flux (20-200 micromoles m-2 s-1). The number of Euglena cells in a certain volume of solution was monitored with a microscope under each environmental condition. The multiplication rate of the cells was highest at temperatures of 27-31 degrees C, CO2 concentration of 4%, O2 concentration of 20% and photosynthetic photon flux of about 100 micromoles m-2 s-1. The results demonstrate that E. gracilis could efficiently produce biomass and convert CO2 to O2 under relatively low light intensities in aquatic food production modules. c2005 Published by Elsevier Ltd on behalf of COSPAR.

Fragmentation studies of relativistic iron ions using plastic nuclear track detectors.

PubMed

Scampoli, P; Durante, M; Grossi, G; Manti, L; Pugliese, M; Gialanella, G

2005-01-01

We measured fluence and fragmentation of high-energy (1 or 5 A GeV) 56Fe ions accelerated at the Alternating Gradient Synchrotron or at the NASA Space Radiation Laboratory (Brookhaven National Laboratory, NY, USA) using solid-state CR-39 nuclear track detectors. Different targets (polyethylene, PMMA, C, Al, Pb) were used to produce a large spectrum of charged fragments. CR-39 plastics were exposed both in front and behind the shielding block (thickness ranging from 5 to 30 g/cm2) at a normal incidence and low fluence. The radiation dose deposited by surviving Fe ions and charged fragments was measured behind the shield using an ionization chamber. The distribution of the measured track size was exploited to distinguish the primary 56Fe ions tracks from the lighter fragments. Measurements of projectile's fluence in front of the shield were used to determine the dose per incident particle behind the block. Simultaneous measurements of primary 56Fe ion tracks in front and behind the shield were used to evaluate the fraction of surviving iron projectiles and the total charge-changing fragmentation cross-section. These physical measurements will be used to characterize the beam used in parallel biological experiments. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

76 FR 79057 - Appliance Labeling Rule

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-21

...) television labels (76 FR 1038 (Jan. 6, 2011)). The effective dates of these two final rules differ. The television label amendments, published on January 6, 2011, became effective on May 10, 2011 while the earlier... ANSI C78.20-2003 and C79.1-2002) and that uses not more than 40 watts or has a length of more than 10...

VizieR Online Data Catalog: RR Tel JHKL photometry 1975-2002 (Kotnik-Karuza+, 2006)

NASA Astrophysics Data System (ADS)

Kotnik-Karuza, D.; Friedjung, M.; Whitelock, P. A.; Marang, F.; Exter, K.; Keenan, F. P.; Pollacco, D. L.

2006-03-01

The file table1.dat contains a list of JHKL magnitudes monitored from the South African Astronomical Observatory (SAAO) from 1975 to 2002. The JHKL magnitudes are accurate to better than 0.03mag in JHK and 0.05mag at L. Some of the early data, which had been published in Feast et al. (1983MNRAS.202..951F), were subsequently slightly corrected to the SAAO system as defined by Carter (1990MNRAS.242....1C). (1 data file).

Contributing to COSPAR - Contibuting to Expanding the Knowledge Frontier of Space for the Benefit of Humankind

NASA Astrophysics Data System (ADS)

Lopez-Baeza, Ernesto

COSPAR's objectives are to promote -on an international level- scientific research in space, with emphasis on the exchange of results, information and opinions, and to provide a forum, open to all scientists, for the discussion of problems that may affect scientific space research (https://cosparhq.cnes.fr/about/origin-purpose-role). COSPAR played an extraordinary significant role in the past by facilitating the scientific exchange between East and West … and surely contributed to the present fluid and free-flowding situation. COSPAR’s challenge now is to get a similar result by providing opportunities to less developed countries to upgrade their resources to progress on all kinds of research using space means. This presentation shows the activity developed by the Climatology from Satellites Group of the University of Valencia, Spain, during the last 10 years, in different action areas of COSPAR, and in the framework of Commission A on Space Studies of the Earth's Surface, Meteorology and Climate, especially in Sub-Commission A3 on Land Processes and Morphology, as well as in the organisation of some Capacity Building Courses akin to Commission A’s terms of reference. The effort -if any- has always and so far been worthwhile. The Group has learnt a lot, it has notably incresed its capacity for networking, as well as its opportunities to accompany scientists from less developed countries in their scientific growing and development of resources (Give a man a fish and you feed him for a day. Teach a man to fish and you feed him for a lifetime -Chinese proverb … and root and foundation for Capacity Building).

Life Sciences and Space Research 25 (2) Radiation Biology: Topical Meeting of the COSPAR Interdisciplinary Scientific Commission F of the COSPAR 29th Plenary Meeting, Washington, DC, Aug. 28-Sep. 5, 1992

NASA Technical Reports Server (NTRS)

Horneck, G. (Editor); Buecher, H. (Editor); Cox, A. (Editor); Todd, P. (Editor); Yang, T. C. (Editor); Worgul, B. V. (Editor); Donlon, M. (Editor); Atwell, W. (Editor); Shea, M. A. (Editor); Smart, D. F. (Editor)

1994-01-01

Papers presented on long-term exposure to ionizing radiation, obtained from the Long Duration Exposure Facility, included radiation monitoring, radiation effects, and dosimetry. Mechanisms of biological systems, especially cells, under ionizing radiation and relative biological effectiveness were compared. The role of HZE particles as agents of mutation were reported from plant, animal, and in vitro models. Data on known and predicted effects of cosmic rays and other solar radiation on biological systems included differences related to Linear Energy Transfer and heavy ion particles.

Stem cell transplantation for treating Parkinson's disease: Literature analysis based on the Web of Science.

PubMed

Li, Runhui

2012-06-05

To identify global research trends of stem cell transplantation for treating Parkinson's disease using a bibliometric analysis of the Web of Science. We performed a bibliometric analysis of data retrievals for stem cell transplantation for treating Parkinson's disease from 2002 to 2011 using the Web of Science. (a) peer-reviewed articles on stem cell transplantation for treating Parkinson's disease which were published and indexed in the Web of Science; (b) type of articles: original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material and news items; (c) year of publication: 2002-2011. (a) articles that required manual searching or telephone access; (b) we excluded documents that were not published in the public domain; (c) we excluded a number of corrected papers from the total number of articles. (1) Type of literature; (2) annual publication output; (3) distribution according to journals; (4) distribution according to subject areas; (5) distribution according to country; (6) distribution according to institution; (7) comparison of countries that published the most papers on stem cell transplantation from different cell sources for treating Parkinson's disease; (8) comparison of institutions that published the most papers on stem cell transplantation from different cell sources for treating Parkinson's disease in the Web of Science from 2002 to 2011; (9) comparison of studies on stem cell transplantation from different cell sources for treating Parkinson's disease. In total, 1 062 studies on stem cell transplantation for treating Parkinson's disease appeared in the Web of Science from 2002 to 2011, almost one third of which were from American authors and institutes. The number of studies on stem cell transplantation for treating Parkinson's disease had gradually increased over the past 10 years. Papers on stem cell transplantation for treating Parkinson's disease appeared in journals such as Stem Cells and Experimental Neurology. Although the United States published more articles addressing neural stem cell and embryonic stem cell transplantation for treating Parkinson's disease, China ranked first for articles published on bone marrow mesenchymal stem cell transplantation for treating Parkinson's disease. From our analysis of the literature and research trends, we found that stem cell transplantation for treating Parkinson's disease may offer further benefits in regenerative medicine.

Impact-shocked rocks--insights into Archean and extraterrestrial microbial habitats (and sites for prebiotic chemistry?)

NASA Technical Reports Server (NTRS)

Cockell, C. S.

2004-01-01

Impact-shocked gneiss shocked to greater than 10 GPa in the Haughton impact structure in the Canadian High Arctic has an approximately 25-times greater pore surface area than unshocked rocks. These pore spaces provide microhabitats for a diversity of heterotrophic microorganisms and in the near-surface environment of the rocks, where light levels are sufficient, cyanobacteria. Shocked rocks provide a moisture retaining, UV protected microenvironment. During the Archean, when impact fluxes were more than two orders of magnitude higher than today, the shocked-rock habitat was one of the most common terrestrial habitats and might have provided a UV-shielded refugium for primitive life. These potential habitats are in high abundance on Mars where impact crater habitats could have existed over geologic time periods of billions of years, suggesting that impact-shocked rocks are important sites to search for biomolecules in extraterrestrial life detection strategies. In addition to being favourable sites for life, during the prebiotic period of planetary history impact-shocked rocks might have acted as a site for the concentration of reactants for prebiotic syntheses. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Genetic analysis of the gravitropic set-point angle in lateral roots of Arabidopsis

NASA Technical Reports Server (NTRS)

Mullen, J. L.; Hangarter, R. P.; Kiss, J. Z. (Principal Investigator)

2003-01-01

Research on gravity responses in plants has mostly focused on primary roots and shoots, which typically orient to a vertical orientation. However, the distribution of lateral organs and their characteristically non-vertical growth orientation are critical for the determination of plant form. For example, in Arabidopsis, when lateral roots emerge from the primary root, they grow at a nearly horizontal orientation. As they elongate, the roots slowly curve until they eventually reach a vertical orientation. The regulation of this lateral root orientation is an important component affecting overall root system architecture. We found that this change in orientation is not simply due to the onset of gravitropic competence, as non-vertical lateral roots are capable of both positive and negative gravitropism. Thus, the horizontal growth of new lateral roots appears to be determined by what is called the gravitropic set-point angle (GSA). This developmental control of the GSA of lateral roots in Arabidopsis provides a useful system for investigating the components involved in regulating gravitropic responses. Using this system, we have identified several Arabidopsis mutants that have altered lateral root orientations but maintain normal primary root orientation. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Impact-shocked rocks--insights into Archean and extraterrestrial microbial habitats (and sites for prebiotic chemistry?).

PubMed

Cockell, C S

2004-01-01

Impact-shocked gneiss shocked to greater than 10 GPa in the Haughton impact structure in the Canadian High Arctic has an approximately 25-times greater pore surface area than unshocked rocks. These pore spaces provide microhabitats for a diversity of heterotrophic microorganisms and in the near-surface environment of the rocks, where light levels are sufficient, cyanobacteria. Shocked rocks provide a moisture retaining, UV protected microenvironment. During the Archean, when impact fluxes were more than two orders of magnitude higher than today, the shocked-rock habitat was one of the most common terrestrial habitats and might have provided a UV-shielded refugium for primitive life. These potential habitats are in high abundance on Mars where impact crater habitats could have existed over geologic time periods of billions of years, suggesting that impact-shocked rocks are important sites to search for biomolecules in extraterrestrial life detection strategies. In addition to being favourable sites for life, during the prebiotic period of planetary history impact-shocked rocks might have acted as a site for the concentration of reactants for prebiotic syntheses. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

A Mobile Asteroid Surface Scout (MASCOT) for the Hayabusa 2 Mission to 1999 JU3: The Scientific Approach

NASA Astrophysics Data System (ADS)

Jaumann, Ralf; Bibring, Jean-Pierre; Glassmeier, Karl-Heinz; Grott, Matthias; Ho, Tra-Mie; Ulamec, Stephan; Schmitz, Nicole; Auster, Hans-Ulrich; Biele, Jens; Kuninaka, Hitoshi; Okada, Tatsuaki; Yoshikawa, Makoto; Watanabe, Sei-ichhiro; Fujimoto, Masaki; Spohn, Tilman

2013-04-01

Mascot, a Mobile Asteroid Surface Scout, will support JAXA's Hayabusa 2 mission to investigate the C-type asteroid 1999 JU3 (1). The German Aero-space Center (DLR) develops Mascot with contributions from CNES (France) (2). Main objective is to in-situ map the asteroid's geomorphology, the intimate structure, texture and composition of the regolith (dust, soil and rocks), and the thermal, mechanical, and magnetic properties of the surface in order to provide ground truth for the orbiter remote measurements, sup-port the selection of sampling sites, and provide context information for the returned samples. Mascot comprises a payload of four scientific instruments: camera, radiometer, magnetometer and hyperspectral microscope. C- and D-type asteroids hold clues to the origin of the solar system, the formation of planets, the origins of water and life on Earth, the protection of Earth from impacts, and resources for future human exploration. C- and D-types are dark and difficult to study from Earth, and have only been glimpsed by spacecraft. While results from recent missions (e.g., Hayabusa, NEAR (3, 4, 5)) have dramatically increased our understanding of asteroids, important questions remain. For example, characterizing the properties of asteroid reg-olith in-situ would deliver important ground truth for further understanding telescopic and orbital observations and samples of such asteroids. Mascot will descend and land on the asteroid and will change its position two times by hopping. This enables measurements during descent, at the landing and hopping positions #1-3, and during hopping. References: (1) Vilas, F., Astronomical J. 1101-1105, 2008; (2) Ulamec, S., et al., COSPAR, General Assembly, Mysore/India, 2012; (3) Special Issue, Science, Vol. 312 no. 5778, 2006; (4) Special Issue Science, Vol. 333 no. 6046, 2011; (5) Bell, L., Mitton, J-., Cambridge Univ. Press, 2002.

Aquatic food production modules in bioregenerative life support systems based on higher plants.

PubMed

Bluem, V; Paris, F

2001-01-01

Most bioregenerative life support systems (BLSS) are based on gravitropic higher plants which exhibit growth and seed generation disturbances in microgravity. Even when used for a lunar or martian base the reduced gravity may induce a decreased productivity in comparison to Earth. Therefore, the implementation of aquatic biomass production modules in higher plant and/or hybrid BLSS may compensate for this and offer, in addition, the possibility to produce animal protein for human nutrition. It was shown on the SLS-89 and SLS-90 space shuttle missions with the C.E.B.A.S.-MINI MODULE that the edible non gravitropic rootless higher aquatic plant Ceratophyllum demeresum exhibits an undisturbed high biomass production rate in space and that the teleost fish species, Xiphophorus helleri, adapts rapidly to space conditions without loss of its normal reproductive functions. Based on these findings a series of ground-based aquatic food production systems were developed which are disposed for utilization in space. These are plant production bioreactors for the species mentioned above and another suitable candidate, the lemnacean (duckweed) species, Wolffia arrhiza. Moreover, combined intensive aquaculture systems with a closed food loop between herbivorous fishes and aquatic and land plants are being developed which may be suitable for integration into a BLSS of higher complexity. Grant numbers: WS50WB9319-3, IVA1216-00588. c 2001. COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Displays in space.

PubMed

Colford, Nicholas

2002-04-01

This chapter describes the human and environmental factors that dictate the way that displays must be designed for, and used in space. A brief history of the evolution of such display systems covers developments from the Mercury rockets to the International Space Station. c2002 Published by Elsevier Science B.V.

Twenty years of space radiation physics at the BNL AGS and NASA Space Radiation Laboratory.

PubMed

Miller, J; Zeitlin, C

2016-06-01

Highly ionizing atomic nuclei HZE in the GCR will be a significant source of radiation exposure for humans on extended missions outside low Earth orbit. Accelerators such as the LBNL Bevalac and the BNL AGS, designed decades ago for fundamental nuclear and particle physics research, subsequently found use as sources of GCR-like particles for ground-based physics and biology research relevant to space flight. The NASA Space Radiation Laboratory at BNL was constructed specifically for space radiation research. Here we review some of the space-related physics results obtained over the first 20 years of NASA-sponsored research at Brookhaven. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

A Reference Model for Middle Atmosphere Ozone in 1992/1993: Differences from That of Keating et al (1996)

NASA Technical Reports Server (NTRS)

Wang, H. J.; Cunnold, D. M.

2002-01-01

Ozone distributions have been derived from recent satellite-based measurements by the Stratospheric Aerosol and Gas Experiment (SAGE), the Halogen Occultation Experiment (HALOE) and the Microwave Limb Sounder (MLS). An ozone distribution for the period April 1992 to March 1993 and covering pressures from 0.1 to 100 mb and from 80 deg N to 80 deg S is summarized. At pressures less than 1 mb, separate distributions are given for daytime and nighttime conditions. The resulting distributions extend to somewhat higher latitudes and lower altitudes than previous COSPAR reference atmosphere distributions for ozone. Differences versus the most recent COSPAR distribution by Keating et al are illustrated.

Use of acupuncture to treat cerebral infarction in the last 10 years: A Scopus-based literature analysis.

PubMed

Chen, Jiajun; Yao, Min; Zhao, Yunhua; Jin, Xiya; Li, Yuanbing; Huang, Lihong

2012-12-25

To identify global research trends in the use of acupuncture to treat cerebral infarction. We performed a bibliometric analysis of studies on the use of acupuncture to treat cerebral infarction published during 2002-2011, retrieved from Scopus, using the key words of acupuncture and cerebral infarction or ischemic stroke. peer-reviewed articles on the use of acupuncture to treat cerebral infarction indexed in Scopus and published between 2002 and 2011; types of publications were original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. articles that required manual searching or telephone access; documents that were not published in the public domain; and corrected papers. (a) Annual publication output; (b) language of publication; (c) type of publication; (d) key words of publication; (e) publication by research field; (f) publication by journal; (g) publication by country and institution; (h) publication by author; (i) most-cited papers between 2002 and 2006; and (j) most-cited papers between 2007 and 2011. A total of 160 publications on the use of acupuncture to treat cerebral infarction from 2002-2011 were retrieved from Scopus. The number of publications increased gradually over the 10-year study period; most were written in Chinese or English. Articles and reviews constituted the major types. The most frequent key word used was acupuncture. The most prolific journals in this area were Zhongguo Zhen Jiu and the Chinese Journal of Clinical Rehabilitation. Of the 160 publications retrieved, half came from Chinese authors and institutions. Tianjin University of Traditional Chinese Medicine was the most prolific research institute. Two papers were cited 30 times; they were published in 2002 and 2009, respectively. In the field of neuroscience, there is little literature on acupuncture for cerebral infarction. The most-cited papers were cited 30 times in the past 3 years. We believe that, with advances in the study of mechanisms in neurobiology, research on acupuncture will also advance and will become the concern of more scholars.

Social Network Analysis and Soldier Resilience

DTIC Science & Technology

2011-04-01

Mental Disorders (4th Edition ed.). (1994). Washington D.C.: American Psychological Association. A manual published by the APA which contains...Psychological Association ( APA ) Diagnostic Manual of Mental Disorders (DSM) (Yehuda, 2002). Definition In order to be diagnosed with PTSD, a person...Approved for public release; distribution is unlimited Note: The views

Human Exploration on the Moon, Mars and NEOs: PEX.2/ICEUM12B

NASA Astrophysics Data System (ADS)

Foing, Bernard H.

2016-07-01

The session COSPAR-16-PEX.2: "Human Exploration on the Moon, Mars and NEOs", co-sponsored by Commissions B, F will include solicited and contributed talks and poster/interactive presentations. It will also be part of the 12th International Conference on Exploration and Utilisation of the Moon ICEUM12B from the ILEWG ICEUM series started in 1994. It will address various themes and COSPAR communities: - Sciences (of, on, from) the Moon enabled by humans - Research from cislunar and libration points - From robotic villages to international lunar bases - Research from Mars & NEOs outposts - Humans to Phobos/Deimos, Mars and NEOS - Challenges and preparatory technologies, field research operations - Human and robotic partnerships and precursor missions - Resource utilisation, life support and sustainable exploration - Stakeholders for human exploration One half-day session will be dedicated to a workshop format and meetings/reports of task groups: Science, Technology, Agencies, Robotic village, Human bases, Society & Commerce, Outreach, Young Explorers. COSPAR has provided through Commissions, Panels and Working Groups (such as ILEWG, IMEWG) an international forum for supporting and promoting the robotic and human exploration of the Moon, Mars and NEOS. Proposed sponsors : ILEWG, ISECG, IKI, ESA, NASA, DLR, CNES, ASI, UKSA, JAXA, ISRO, SRON, CNSA, SSERVI, IAF, IAA, Lockheed Martin, Google Lunar X prize, UNOOSA

Microbial life in permafrost.

PubMed

Rivkina, E; Laurinavichius, K; McGrath, J; Tiedje, J; Shcherbakova, V; Gilichinsky, D

2004-01-01

Hydrogenotrophic and acetoclastic methanogenesis was measured at temperatures between 5 and -16.5 degrees C with H14CO3- and 14CH3CO2- as substrates in Siberian permafrost soils. The rate of methane formation was reduced approximately 2-fold over the temperature range from 5 to -1.8 degrees C. For the most active sample "a" temperature dependence of CH4, production at negative temperatures was approximately a 100-fold reduction for a range of -1.8 to -16.5 degrees C for both substrates. According to the Arrhenius equation, the activation energy of methane generation from bicarbonate and acetate for the temperature interval -5 to -16.5 degrees C was reduced by a factor of 3 and 1.5, respectively, in comparison with the temperatures above zero. In the experiments we tested the geological time series, showing the ability of microorganisms to carry out redox reactions after thousands to millions years of existence in permafrost. From the Climate Change point of view, it is important that the recovered organisms are quickly involved anew in present-day ecological processes after instances of permafrost thawing, and may be vital in nutrient recycling and in the production and consumption of greenhouse gases over a large portion of the Earth's surface. From an exobiological point of view, the terrestrial permafrost, inhabited by cold adapted microbes and protecting the cells against unfavorable conditions, can be considered as an extraterrestrial model. The methanogenic bacteria and their metabolic end-products found in the Earth's permafrost provide a range of analogues that could be used in the search for possible ecosystems and potential inhabitants on extraterrestrial cryogenic bodies free of oxygen. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Theory, Instrumentation and Applications of Magnetoelastic Resonance Sensors: A Review

PubMed Central

Grimes, Craig A.; Roy, Somnath C.; Rani, Sanju; Cai, Qingyun

2011-01-01

Thick-film magnetoelastic sensors vibrate mechanically in response to a time varying magnetic excitation field. The mechanical vibrations of the magnetostrictive magnetoelastic material launch, in turn, a magnetic field by which the sensor can be monitored. Magnetic field telemetry enables contact-less, remote-query operation that has enabled many practical uses of the sensor platform. This paper builds upon a review paper we published in Sensors in 2002 (Grimes, C.A.; et al. Sensors 2002, 2, 294–313), presenting a comprehensive review on the theory, operating principles, instrumentation and key applications of magnetoelastic sensing technology. PMID:22163768

The Excellent Inevitability of Online Courses

ERIC Educational Resources Information Center

Brooks, Margaret

2009-01-01

Online enrollments have grown much faster than overall higher-education enrollments over the past few years, according to a 2008 report, "Staying the Course: Online Education in the United States," published by the Sloan-C, a consortium that promotes online education. During the period 2002-7, enrollment in online courses grew 19.7 percent,…

A homozygous PMS2 founder mutation with an attenuated constitutional mismatch repair deficiency phenotype.

PubMed

Li, Lili; Hamel, Nancy; Baker, Kristi; McGuffin, Michael J; Couillard, Martin; Gologan, Adrian; Marcus, Victoria A; Chodirker, Bernard; Chudley, Albert; Stefanovici, Camelia; Durandy, Anne; Hegele, Robert A; Feng, Bing-Jian; Goldgar, David E; Zhu, Jun; De Rosa, Marina; Gruber, Stephen B; Wimmer, Katharina; Young, Barbara; Chong, George; Tischkowitz, Marc D; Foulkes, William D

2015-05-01

Inherited mutations in DNA mismatch repair genes predispose to different cancer syndromes depending on whether they are mono-allelic or bi-allelic. This supports a causal relationship between expression level in the germline and phenotype variation. As a model to study this relationship, our study aimed to define the pathogenic characteristics of a recurrent homozygous coding variant in PMS2 displaying an attenuated phenotype identified by clinical genetic testing in seven Inuit families from Northern Quebec. Pathogenic characteristics of the PMS2 mutation NM_000535.5:c.2002A>G were studied using genotype-phenotype correlation, single-molecule expression detection and single genome microsatellite instability analysis. This PMS2 mutation generates a de novo splice site that competes with the authentic site. In homozygotes, expression of the full-length protein is reduced to a level barely detectable by conventional diagnostics. Median age at primary cancer diagnosis is 22 years among 13 NM_000535.5:c.2002A>G homozygotes, versus 8 years in individuals carrying bi-allelic truncating mutations. Residual expression of full-length PMS2 transcript was detected in normal tissues from homozygotes with cancers in their 20s. Our genotype-phenotype study of c.2002A>G illustrates that an extremely low level of PMS2 expression likely delays cancer onset, a feature that could be exploited in cancer preventive intervention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Earth GRAM-99 and Trace Constituents

NASA Technical Reports Server (NTRS)

Justus, C. G.; Duvall, Aleta; Keller, Vernon W.

2004-01-01

Global Reference Atmospheric Model (GRAM-99) is an engineering-level model of Earth's atmosphere. It provides both mean values and perturbations for density, temperature, pressure, and winds, as well as monthly- and geographically-varying trace constituent concentrations. From 0-27 km, GRAM thermodynamics and winds are based on National Oceanic and Atmospheric Administration Global Upper Air Climatic Atlas (GUACA) climatology. Above 120 km, GRAM is based on the NASA Marshall Engineering Thermosphere (MET) model. In the intervening altitude region, GRAM is based on Middle Atmosphere Program (MAP) climatology that also forms the basis of the 1986 COSPAR International Reference Atmosphere (CIRA). Atmospheric composition is represented in GRAM by concentrations of both major and minor species. Above 120 km, MET provides concentration values for N2, O2, Ar, O, He, and H. Below 120 km, species represented also include H2O, O3, N2O, CO, CH4, and CO2. At COSPAR 2002 a comparison was made between GRAM constituents below 120 km and those provided by Naval Research Laboratory (NRL) climatology. No current need to update GRAM constituent climatology in that height range was identified. This report examines GRAM (MET) constituents between 100 and 1000 km altitudes. Discrepancies are noted between GRAM (MET) constituent number densities and mass density or molecular weight. Near 110 km altitude, there is up to about 25% discrepancy between MET number density and mass density (with mass density being valid and number densities requiring adjustment). Near 700 km altitude there is also up to about 25% discrepancy between MET number density and mean molecular weight (with molecular weight requiring adjustment). In neither case are MET mass density estimates invalidated. These discrepancies have been traced to MET subroutines SLV (which affects 90-170 km height range) and SLVH (which affects helium above 440 km altitude). With these discrepancies corrected, results are presented to illustrate GRAM (MET) constituent mole fractions in terms of height-latitude cross sections from 100 to 1000 km altitude, and latitude-longitude 'maps' at 450 km (approximate height of International Space Station). Plans are discussed for an update of MET (and GRAM) to correct these constituent inconsistencies and to incorporate several new thermospheric model features.

Structure of the Venusian atmosphere from surface up to 100 km

NASA Astrophysics Data System (ADS)

Zasova, L. V.; Moroz, V. I.; Linkin, V. M.; Khatuntsev, I. V.; Maiorov, B. S.

2006-07-01

The goal of this paper is to summarize the experimental data on the atmosphere of Venus obtained after 1985, when the VIRA (Venus International Reference Atmosphere) or COSPAR model was published. Among the most important results that have appeared since then are the following: measurements of the vertical temperature profile by the VEGA spacecraft with high precision and high altitude resolution; measurements made with balloons of the VEGA spacecraft; radio occultation measurements of Magellan, Venera-15, and Venera-16; and temperature profiles derived from the data of infrared spectrometry obtained by Venera-15. The new result as compared to VIRA is the creation of a model of the atmosphere in the altitude range 55 to 100 km dependent on local time. This model is presented in our paper in tabulated form.

From the desk of the Editor-in-Chief

NASA Astrophysics Data System (ADS)

2014-10-01

Launching a new journal is never an easy endeavor. With the publication of this issue of the Life Sciences in Space Research, our new Journal has gotten off to an excellent start with thirty scholarly articles published since its inception and a steady stream of submissions. At the 40th COSPAR assembly held at the picturesque campus of Moscow State University in early August, Elsevier sponsored an inaugural event to promote the launching of the journal, an event that was well attended if one were to use how fast the food platter disappeared as a yardstick. In addition, at the recent Radiation Research Society meeting in Las Vegas in the U.S., Elsevier had an exhibition booth (picture), which was visited by many of the NASA and ESA funded scientists attending the meeting.

Stem cell transplantation for treating Duchenne muscular dystrophy: A Web of Science-based literature analysis.

PubMed

Yang, Xiaofeng

2012-08-05

To identify global research trends in stem cell transplantation for treating Duchenne muscular dystrophy using a bibliometric analysis of Web of Science. We performed a bibliometric analysis of studies on stem cell transplantation for treating Duchenne muscular dystrophy from 2002 to 2011 retrieved from Web of Science. (a) peer-reviewed published articles on stem cell transplantation for treating Duchenne muscular dystrophy indexed in Web of Science; (b) original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items; and (c) publication between 2002 and 2011. (a) articles that required manual searching or telephone access; (b) documents that were not published in the public domain; and (c) corrected papers. (1) Annual publication output; (2) distribution according to subject areas; (3) distribution according to journals; (4) distribution according to country; (5) distribution according to institution; (6) distribution according to institution in China; (7) distribution according to institution that cooperated with Chinese institutions; (8) top-cited articles from 2002 to 2006; (9) top-cited articles from 2007 to 2011. A total of 318 publications on stem cell transplantation for treating Duchenne muscular dystrophy were retrieved from Web of Science from 2002 to 2011, of which almost half derived from American authors and institutes. The number of publications has gradually increased over the past 10 years. Most papers appeared in journals with a focus on gene and molecular research, such as Molecular Therapy, Neuromuscular Disorders, and PLoS One. The 10 most-cited papers from 2002 to 2006 were mostly about different kinds of stem cell transplantation for muscle regeneration, while the 10 most-cited papers from 2007 to 2011 were mostly about new techniques of stem cell transplantation for treating Duchenne muscular dystrophy. The publications on stem cell transplantation for treating Duchenne muscular dystrophy were relatively few. It also needs more research to confirm that stem cell therapy is a reliable treatment for Duchenne muscular dystrophy.

COSPAR Round Table on `How can GEO and COSPAR scientific community work together?'

NASA Astrophysics Data System (ADS)

Gobron, Nadine; Ollier, Gilles

The Group on Earth Observations is coordinating efforts to build a Global Earth Observation System of Systems, or GEOSS. GEO is a voluntary partnership of governments and inter-national organizations. It provides a framework within which these partners can develop new projects and coordinate their strategies and investments. The Science and Technology Commit-tee of GEO is working to strengthen this role by encouraging the wider scientific and technology community to participate as contributors to and benefactors of a sustained GEOSS. The proposed round table aims at discussing how are scientists and GEO currently working together, using specific examples and how do space agencies or data providers contribute to GEO? Round table participants are welcome to present their own vision on future actions to improve, if necessary, the relations between contributors and GEO. Meeting participants will also be offered the opportunity to intervene and ask questions to the panel. Moderators: • Dr. Nadine Gobron -EC-JRC -Chair of Commission A • Gilles Ollier -DG Research Participants: • Prof. José Achache -Director of GEO • Prof. Maurice Bonnet -President of COSPAR • Dr. Tamatsu Igarashi -JAXA EORC Manager • Dr. Stuart Minchin (CSIRO and member of GEO STC) TBC • Prof. Berrien Moore -Executive Director of Climate Central • Dr. Diane E. Wickland -NASA Headquarters • Dr. Stephen Briggs -ESA (TBC)

Planetary Protection and Mars Special Regions--A Suggestion for Updating the Definition.

PubMed

Rettberg, Petra; Anesio, Alexandre M; Baker, Victor R; Baross, John A; Cady, Sherry L; Detsis, Emmanouil; Foreman, Christine M; Hauber, Ernst; Ori, Gian Gabriele; Pearce, David A; Renno, Nilton O; Ruvkun, Gary; Sattler, Birgit; Saunders, Mark P; Smith, David H; Wagner, Dirk; Westall, Frances

2016-02-01

We highlight the role of COSPAR and the scientific community in defining and updating the framework of planetary protection. Specifically, we focus on Mars "Special Regions," areas where strict planetary protection measures have to be applied before a spacecraft can explore them, given the existence of environmental conditions that may be conducive to terrestrial microbial growth. We outline the history of the concept of Special Regions and inform on recent developments regarding the COSPAR policy, namely, the MEPAG SR-SAG2 review and the Academies and ESF joint committee report on Mars Special Regions. We present some new issues that necessitate the update of the current policy and provide suggestions for new definitions of Special Regions. We conclude with the current major scientific questions that remain unanswered regarding Mars Special Regions.

Effects of spaceflight on the immunoglobulin repertoire of unimmunized C57BL/6 mice.

PubMed

Ward, Claire; Rettig, Trisha A; Hlavacek, Savannah; Bye, Bailey A; Pecaut, Michael J; Chapes, Stephen K

2018-02-01

Spaceflight has been shown to suppress the adaptive immune response, altering the distribution and function of lymphocyte populations. B lymphocytes express highly specific and highly diversified receptors, known as immunoglobulins (Ig), that directly bind and neutralize pathogens. Ig diversity is achieved through the enzymatic splicing of gene segments within the genomic DNA of each B cell in a host. The collection of Ig specificities within a host, or Ig repertoire, has been increasingly characterized in both basic research and clinical settings using high-throughput sequencing technology (HTS). We utilized HTS to test the hypothesis that spaceflight affects the B-cell repertoire. To test this hypothesis, we characterized the impact of spaceflight on the unimmunized Ig repertoire of C57BL/6 mice that were flown aboard the International Space Station (ISS) during the Rodent Research One validation flight in comparison to ground controls. Individual gene segment usage was similar between ground control and flight animals, however, gene segment combinations and the junctions in which gene segments combine was varied among animals within and between treatment groups. We also found that spontaneous somatic mutations in the IgH and Igκ gene loci were not increased. These data suggest that space flight did not affect the B cell repertoire of mice flown and housed on the ISS over a short period of time. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Mimicking the effects of spaceflight on bone: Combined effects of disuse and chronic low-dose rate radiation exposure on bone mass in mice.

PubMed

Yu, Kanglun; Doherty, Alison H; Genik, Paula C; Gookin, Sara E; Roteliuk, Danielle M; Wojda, Samantha J; Jiang, Zhi-Sheng; McGee-Lawrence, Meghan E; Weil, Michael M; Donahue, Seth W

2017-11-01

During spaceflight, crewmembers are subjected to biomechanical and biological challenges including microgravity and radiation. In the skeleton, spaceflight leads to bone loss, increasing the risk of fracture. Studies utilizing hindlimb suspension (HLS) as a ground-based model of spaceflight often neglect the concomitant effects of radiation exposure, and even when radiation is accounted for, it is often delivered at a high-dose rate over a very short period of time, which does not faithfully mimic spaceflight conditions. This study was designed to investigate the skeletal effects of low-dose rate gamma irradiation (8.5 cGy gamma radiation per day for 20 days, amounting to a total dose of 1.7 Gy) when administered simultaneously to disuse from HLS. The goal was to determine whether continuous, low-dose rate radiation administered during disuse would exacerbate bone loss in a murine HLS model. Four groups of 16 week old female C57BL/6 mice were studied: weight bearing + no radiation (WB+NR), HLS + NR, WB + radiation exposure (WB+RAD), and HLS+RAD. Surprisingly, although HLS led to cortical and trabecular bone loss, concurrent radiation exposure did not exacerbate these effects. Our results raise the possibility that mechanical unloading has larger effects on the bone loss that occurs during spaceflight than low-dose rate radiation. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Oxygen requirement of germinating flax seeds.

PubMed

Kuznetsov, Oleg A; Hasenstein, K H

2003-01-01

Plant experiments in earth orbit are typically prepared on the ground and germinated in orbit to study gravity effects on the developing seedlings. Germination requires the breakdown of storage compounds, and this metabolism depends upon respiration, making oxygen one of the limiting factors in seed germination. In microgravity lack of run-off of excess water requires careful testing of water dispensation and oxygen availability. In preparation for a shuttle experiment (MICRO on STS-107) we studied germination and growth of flax (Linum usitatissimum L.) seedlings in the developed hardware (Magnetic Field Chamber, MFC). We tested between four to 32 seeds per chamber (air volume=14 mL) and after 36 h measured the root length. At 90 microliters O2 per seed (32 seeds/chamber), the germination decreased from 94 to 69%, and the root length was reduced by 20%, compared to 8 seeds per chamber. Based on the percent germination and root length obtained in controlled gas mixtures between 3.6 and 21.6% O2 we determined the lower limit of reliable germination to be 10 vol. % O2 at atmospheric pressure. Although the oxygen available in the MFC's can support the intended number of seeds, the data show that seed storage and microgravity-related limitations may reduce germination. c2003 Published by Elsevier Ltd on behalf of COSPAR.

A new Mars radiation environment model with visualization

NASA Technical Reports Server (NTRS)

De Angelis, G.; Clowdsley, M. S.; Singleterry, R. C.; Wilson, J. W.

2004-01-01

A new model for the radiation environment to be found on the planet Mars due to Galactic Cosmic Rays (OCR) has been developed at the NASA Langley Research Center. Solar modulated primary particles rescaled for Mars conditions are transported through the Martian atmosphere, with temporal properties modeled with variable timescales, down to the surface, with altitude and backscattering patterns taken into account. The Martian atmosphere has been modeled by using the Mars Global Reference Atmospheric Model--version 2001 (Mars-GRAM 2001). The altitude to compute the atmospheric thickness profile has been determined by using a model for the topography based on the data provided by the Mars Orbiter Laser Altimeter (MOLA) instrument on board the Mars Global Surveyor (MGS) spacecraft. The Mars surface composition has been modeled based on averages over the measurements obtained from orbiting spacecraft and at various landing sites, taking into account the possible volatile inventory (e.g., CO2 ice, H2O ice) along with its time variation throughout the Martian year. Particle transport has been performed with the HZETRN heavy ion code. The Mars Radiation Environment Model has been made available worldwide through the Space Ionizing Radiation Effects and Shielding Tools (SIREST) website, a project of NASA Langley Research Center. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Pre-biotic stage of life origin under non-photosynthetic conditions

NASA Technical Reports Server (NTRS)

Bartsev, S. I.; Mezhevikin, V. V.

2005-01-01

Spontaneous assembling of a simplest bacterial cell even if all necessary molecules are present in a solution seems to be extremely rare event and from the scientific standpoint has to be considered as impossible. Therefore, a predecessor of a living cell has to be very simple for providing its self-assembling and at the same time it should be able of progressive increase in complexity. Now phase-separated particles, first of all micelles, are put forward as possible predecessors of living cell. According to the offered working concept only phase-separated particles possessing autocatalytic properties can be considered as predecessors of living cells. The first stage of evolution of these phase-separated autocatalytic systems is the appearance of pre-biotic metabolism providing synthesis of amphiphiles for formation of capsules of these systems. This synthesis is maintained by the energy of a base reaction being a component of a planet-chemical cycle. Catalytic system providing functioning of pre-biotic metabolism is based on multivariate oligomeric autocatalyst, which reproduces itself from monomers, penetrating the particles from the outside. Since the autocatalyst realizes random polymerization then a collection of other oligomers possessing different catalytic functions is produced. In the paper the functioning of multivariate oligomeric autocatalyst in flow reactor is analyzed. c2005 Published by Elsevier Ltd on behalf of COSPAR.

The ALTEA/ALTEINO projects: studying functional effects of microgravity and cosmic radiation

NASA Technical Reports Server (NTRS)

Narici, L.; Belli, F.; Bidoli, V.; Casolino, M.; De Pascale, M. P.; Di Fino, L.; Furano, G.; Modena, I.; Morselli, A.; Picozza, P.;

Radiation analysis for manned missions to the Jupiter system

NASA Technical Reports Server (NTRS)

De Angelis, G.; Clowdsley, M. S.; Nealy, J. E.; Tripathi, R. K.; Wilson, J. W.

2004-01-01

An analysis for manned missions targeted to the Jovian system has been performed in the framework of the NASA RASC (Revolutionary Aerospace Systems Concepts) program on Human Exploration beyond Mars. The missions were targeted to the Jupiter satellite Callisto. The mission analysis has been divided into three main phases, namely the interplanetary cruise, the Jupiter orbital insertion, and the surface landing and exploration phases. The interplanetary phase is based on departure from the Earth-Moon L1 point. Interplanetary trajectories based on the use of different propulsion systems have been considered, with resulting overall cruise phase duration varying between two and five years. The Jupiter-approach and the orbital insertion trajectories are considered in detail, with the spacecraft crossing the Jupiter radiation belts and staying around the landing target. In the surface exploration phase the stay on the Callisto surface is considered. The satellite surface composition has been modeled based on the most recent results from the GALILEO spacecraft. In the transport computations the surface backscattering has been duly taken into account. Particle transport has been performed with the HZETRN heavy ion code for hadrons and with an in-house developed transport code for electrons and bremsstrahlung photons. The obtained doses have been compared to dose exposure limits. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Oxygen requirement of germinating flax seeds

NASA Technical Reports Server (NTRS)

Kuznetsov, Oleg A.; Hasenstein, K. H.; Hasentein, K. H. (Principal Investigator)

2003-01-01

Plant experiments in earth orbit are typically prepared on the ground and germinated in orbit to study gravity effects on the developing seedlings. Germination requires the breakdown of storage compounds, and this metabolism depends upon respiration, making oxygen one of the limiting factors in seed germination. In microgravity lack of run-off of excess water requires careful testing of water dispensation and oxygen availability. In preparation for a shuttle experiment (MICRO on STS-107) we studied germination and growth of flax (Linum usitatissimum L.) seedlings in the developed hardware (Magnetic Field Chamber, MFC). We tested between four to 32 seeds per chamber (air volume=14 mL) and after 36 h measured the root length. At 90 microliters O2 per seed (32 seeds/chamber), the germination decreased from 94 to 69%, and the root length was reduced by 20%, compared to 8 seeds per chamber. Based on the percent germination and root length obtained in controlled gas mixtures between 3.6 and 21.6% O2 we determined the lower limit of reliable germination to be 10 vol. % O2 at atmospheric pressure. Although the oxygen available in the MFC's can support the intended number of seeds, the data show that seed storage and microgravity-related limitations may reduce germination. c2003 Published by Elsevier Ltd on behalf of COSPAR.

Earth applications of closed ecological systems: relevance to the development of sustainability in our global biosphere.

PubMed

Nelson, M; Allen, J; Alling, A; Dempster, W F; Silverstone, S

2003-01-01

The parallels between the challenges facing bioregenerative life support in artificial closed ecological systems and those in our global biosphere are striking. At the scale of the current global technosphere and expanding human population, it is increasingly obvious that the biosphere can no longer safely buffer and absorb technogenic and anthropogenic pollutants. The loss of biodiversity, reliance on non-renewable natural resources, and conversion of once wild ecosystems for human use with attendant desertification/soil erosion, has led to a shift of consciousness and the widespread call for sustainability of human activities. For researchers working on bioregenerative life support in closed systems, the small volumes and faster cycling times than in the Earth's biosphere make it starkly clear that systems must be designed to ensure renewal of water and atmosphere, nutrient recycling, production of healthy food, and safe environmental methods of maintaining technical systems. The development of technical systems that can be fully integrated and supportive of living systems is a harbinger of new perspectives as well as technologies in the global environment. In addition, closed system bioregenerative life support offers opportunities for public education and consciousness changing of how to live with our global biosphere. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

The ALTEA/ALTEINO projects: studying functional effects of microgravity and cosmic radiation.

PubMed

Narici, L; Belli, F; Bidoli, V; Casolino, M; De Pascale, M P; Di Fino, L; Furano, G; Modena, I; Morselli, A; Picozza, P; Reali, E; Rinaldi, A; Ruggieri, D; Sparvoli, R; Zaconte, V; Sannita, W G; Carozzo, S; Licoccia, S; Romagnoli, P; Traversa, E; Cotronei, V; Vazquez, M; Miller, J; Salnitskii, V P; Shevchenko, O I; Petrov, V P; Trukhanov, K A; Galper, A; Khodarovich, A; Korotkov, M G; Popov, A; Vavilov, N; Avdeev, S; Boezio, M; Bonvicini, W; Vacchi, A; Zampa, N; Mazzenga, G; Ricci, M; Spillantini, P; Castellini, G; Vittori, R; Carlson, P; Fuglesang, C; Schardt, D

2004-01-01

The ALTEA project investigates the risks of functional brain damage induced by particle radiation in space. A modular facility (the ALTEA facility) is being implemented and will be operated in the International Space Station (ISS) to record electrophysiological and behavioral descriptors of brain function and to monitor their time dynamics and correlation with particles and space environment. The focus of the program will be on abnormal visual perceptions (often reported as "light flashes" by astronauts) and the impact on retinal and brain visual structures of particle in microgravity conditions. The facility will be made available to the international scientific community for human neurophysiological, electrophysiological and psychophysics experiments, studies on particle fluxes, and dosimetry. A precursor of ALTEA (the 'Alteino' project) helps set the experimental baseline for the ALTEA experiments, while providing novel information on the radiation environment onboard the ISS and on the brain electrophysiology of the astronauts during orbital flights. Alteino was flown to the ISS on the Soyuz TM34 as part of mission Marco Polo. Controlled ground experiments using mice and accelerator beams complete the experimental strategy of ALTEA. We present here the status of progress of the ALTEA project and preliminary results of the Alteino study on brain dynamics, particle fluxes and abnormal visual perceptions. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function

NASA Technical Reports Server (NTRS)

Rabin, B. M.; Joseph, J. A.; Shukitt-Hale, B.

2004-01-01

Exposure to heavy particles can affect the functioning of the central nervous system (CNS), particularly the dopaminergic system. In turn, the radiation-induced disruption of dopaminergic function affects a variety of behaviors that are dependent upon the integrity of this system, including motor behavior (upper body strength), amphetamine (dopamine)-mediated taste aversion learning, and operant conditioning (fixed-ratio bar pressing). Although the relationships between heavy particle irradiation and the effects of exposure depend, to some extent, upon the specific behavioral or neurochemical endpoint under consideration, a review of the available research leads to the hypothesis that the endpoints mediated by the CNS have certain characteristics in common. These include: (1) a threshold, below which there is no apparent effect; (2) the lack of a dose-response relationship, or an extremely steep dose-response curve, depending on the particular endpoint; and (3) the absence of recovery of function, such that the heavy particle-induced behavioral and neural changes are present when tested up to one year following exposure. The current report reviews the data relevant to the degree to which these characteristics are common to neurochemical and behavioral endpoints that are mediated by the effects of exposure to heavy particles on CNS activity. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Radiation analysis for manned missions to the Jupiter system.

PubMed

De Angelis, G; Clowdsley, M S; Nealy, J E; Tripathi, R K; Wilson, J W

2004-01-01

An analysis for manned missions targeted to the Jovian system has been performed in the framework of the NASA RASC (Revolutionary Aerospace Systems Concepts) program on Human Exploration beyond Mars. The missions were targeted to the Jupiter satellite Callisto. The mission analysis has been divided into three main phases, namely the interplanetary cruise, the Jupiter orbital insertion, and the surface landing and exploration phases. The interplanetary phase is based on departure from the Earth-Moon L1 point. Interplanetary trajectories based on the use of different propulsion systems have been considered, with resulting overall cruise phase duration varying between two and five years. The Jupiter-approach and the orbital insertion trajectories are considered in detail, with the spacecraft crossing the Jupiter radiation belts and staying around the landing target. In the surface exploration phase the stay on the Callisto surface is considered. The satellite surface composition has been modeled based on the most recent results from the GALILEO spacecraft. In the transport computations the surface backscattering has been duly taken into account. Particle transport has been performed with the HZETRN heavy ion code for hadrons and with an in-house developed transport code for electrons and bremsstrahlung photons. The obtained doses have been compared to dose exposure limits. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Globalization in Urology: A Bibliographical Analysis of Cross-Continent Publication between 2002 and 2012.

PubMed

Mani, Jens; Juengel, Eva; Bartsch, Georg; Filmann, Natalie; Ackermann, Hanns; Nelson, Karen; Haferkamp, Axel; Engl, Tobias; Blaheta, Roman A

2015-01-01

Asian scientists have now increasingly begun to contribute to globalization; yet it is not clear whether publishing in the field of urology is paralleled by elevated cross-continental scientific publishing. An exemplary bibliometric analysis of urologic journals from 3 different continents was conducted between 2002 and 2012. Based on the ISI Web of Knowledge Journal Citation Reports, 2 urologic journals with similar impact factors (IFs) in 2013 were selected from Europe ('British Journal of Urology International', 'World Journal of Urology'), Asia ('International Journal of Urology', 'Asian Journal of Andrology') and North America ('Urologic Oncology-Seminars and Original Investigations', 'Urology'). The home continent of the journal, the workplace continental affiliation of the last author, article type (clinical, experimental or review) as well as the IF were documented. Most authors published their manuscripts in journals from the same continent in which they worked. However, a significant increase in cross-continental publishing was apparent from 2002 to 2012. Asians publishing in North America increased from 17% in 2002 to 35% in 2012. Europeans also increased the number of articles they published in North American journals, while publications from North American authors were shifted towards both European and Asian journals. Experimental and clinical articles showed significant increases in cross-continental publishing, while review publishing showed no significant change. The average IF for authors from all 3 continents increased from 2002 to 2012 (p < 0.001). The largest increase in the IF was found for Asian authors (0.11 per year). Cross-continental publication significantly increased during the period from 2002 to 2012. The impact that the Asian authors have experienced was found to be gradually impacting the North American and European colleagues. © 2015 S. Karger AG, Basel.

Editorial

NASA Astrophysics Data System (ADS)

2003-06-01

In December 2002 we announced some changes to Journal of Physics B: Atomic, Molecular and Optical Physics: an extended scope to highlight the wide range of articles published in the journal and a new definition of Letters to the Editor. As always, comments and suggestions are welcome and should be sent to jphysb@iop.org. Extended scope of J. Phys. B J. Phys. B covers all aspects of atomic, molecular and optical physics. We publish articles on the study of atoms, ions, molecules, condensates or clusters, from their structure and interactions with particles, photons, fields and surfaces to all aspects of spectroscopy. Quantum optics, non-linear optics, laser physics, astrophysics, plasma physics, chemical physics, optical cooling and trapping and other investigations where the objects of study are the elementary atomic, ionic or molecular properties of processes are also included. With the introduction of the BEC Matters! portal and IOP Select, J. Phys. B, one of the major contributors, offers authors of articles in this research area wider visibility and more flexible publication with the opportunity to display multimedia attachments or web links to key groups and results. The recent papers listed below reflect the wide scope of J. Phys. B: Calculation of cross sections for very low-energy hydrogen-antihydrogen scattering using the Kohn variational method E A G Armour and C W Chamberlain J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 22 (28 November 2002) L489-L494 Imaging the electron transfer reaction of Ne2+ with Ar using position-sensitive coincidence spectroscopy Sarah M Harper, Wan-Ping Hu and Stephen D Price J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 21 (14 November 2002) 4409-4423 Ultraviolet-infrared wavelength scalings for strong field induced L-shell emissions from Kr and Xe clusters Alex B Borisov, Xiangyang Song, Fabrizio Frigeni, Yang Dai, Yevgeniya Koshman, W Andreas Schroeder, Jack Davis, Keith Boyer and Charles K Rhodes J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 21 (14 November 2002) L461-L467 A Bose-Einstein condensate in an optical lattice J Hecker Denschlag, J E Simsarian, H Häffner, C McKenzie, A Browaeys, D Cho, K Helmerson, S L Rolston and W D Phillips J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 14 (28 July 2002) 3095-3110 Locality of a class of entangled states I R Senitzky J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 14 (28 July 2002) 3029-3039 Solitons and vortices in ultracold fermionic gases Tomasz Karpiuk, Miroslaw Brewczyk and Kazimierz Rzazewski J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 14 (28 July 2002) L315-L321 Stable islands in chaotic atom-optics billiards, caused by curved trajectories M F Andersen, A Kaplan, N Friedman and N Davidson J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 9 (14 May 2002) 2183-2190 Emission probability and photon statistics of a coherently driven mazer Jin Xiong and Zhi-Ming Zhang J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 9 (14 May 2002) 2159-2172 The Li+-H2 system in a rigid-rotor approximation: potential energy surface and transport coefficients I Røeggen, H R Skullerud, T H Løvaas and D K Dysthe J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 7 (14 April 2002) 1707-1725 The stochastic Gross-Pitaevskii equation C W Gardiner, J R Anglin and T I A Fudge J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 6 (28 March 2002) 1555-1582 Oxygen ion impurity in the TEXTOR tokamak boundary plasma observed and analysed by Zeeman spectroscopy J D Hey, C C Chu, S Brezinsek, Ph Mertens and B Unterberg J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 6 (28 March 2002) 1525-1553 Electron-hexafluoropropene (C3F6) scattering at intermediate energies Czeslaw Szmytkowski, Pawel Mozejko and Stanislaw Kwitnewski J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 5 (14 March 2002) 1267-1274 High-resolution investigations of C2 and CN optical emissions in laser-induced plasmas during graphite ablation S Acquaviva and M L De Giorgi J. Phys. B: At. Mol. Opt. Phys. Vol 35, No 4 (28 February 2002) 795-806 New definition of a Letter to the Editor A Letter to the Editor should present new results, likely to stimulate further research and be of interest to the wider atomic, molecular and optical physics community. Above all the results should be sufficiently new and important to merit rapid publication as a Letter, which implies accelerated refereeing procedures. This should be made clear either in the body of the Letter, if appropriate, or with a supporting cover letter from the author on submission to the journal. Letters will have an upper limit of eight journal pages and, as an additional quality check, two referees instead of one will be used to review them. The Board will be asked to make a final publication decision in the event of two conflicting reports. With these measures in place it is hoped that the important new results will receive the exposure they deserve as a Letter. If you have any questions or comments on this or anything relating to J. Phys. B please contact Nicola Gulley, Publisher, J. Phys. B (E-mail: jphysb@iop.org).

Use of acupuncture to treat cerebral infarction in the last 10 years: A Scopus-based literature analysis☆

PubMed Central

Chen, Jiajun; Yao, Min; Zhao, Yunhua; Jin, Xiya; Li, Yuanbing; Huang, Lihong

2012-01-01

OBJECTIVE: To identify global research trends in the use of acupuncture to treat cerebral infarction. DATA RETRIEVAL: We performed a bibliometric analysis of studies on the use of acupuncture to treat cerebral infarction published during 2002–2011, retrieved from Scopus, using the key words of acupuncture and cerebral infarction or ischemic stroke. SELECTION CRITERIA: Inclusion criteria: peer-reviewed articles on the use of acupuncture to treat cerebral infarction indexed in Scopus and published between 2002 and 2011; types of publications were original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. Exclusion criteria: articles that required manual searching or telephone access; documents that were not published in the public domain; and corrected papers. MAIN OUTCOME MEASURES: (a) Annual publication output; (b) language of publication; (c) type of publication; (d) key words of publication; (e) publication by research field; (f) publication by journal; (g) publication by country and institution; (h) publication by author; (i) most-cited papers between 2002 and 2006; and (j) most-cited papers between 2007 and 2011. RESULTS: A total of 160 publications on the use of acupuncture to treat cerebral infarction from 2002–2011 were retrieved from Scopus. The number of publications increased gradually over the 10-year study period; most were written in Chinese or English. Articles and reviews constituted the major types. The most frequent key word used was acupuncture. The most prolific journals in this area were Zhongguo Zhen Jiu and the Chinese Journal of Clinical Rehabilitation. Of the 160 publications retrieved, half came from Chinese authors and institutions. Tianjin University of Traditional Chinese Medicine was the most prolific research institute. Two papers were cited 30 times; they were published in 2002 and 2009, respectively. CONCLUSION: In the field of neuroscience, there is little literature on acupuncture for cerebral infarction. The most-cited papers were cited 30 times in the past 3 years. We believe that, with advances in the study of mechanisms in neurobiology, research on acupuncture will also advance and will become the concern of more scholars. PMID:25317148

Educational Technology Research Journals: Computers & Education, 2002-2011

ERIC Educational Resources Information Center

Rackham, David D.; Hyatt, Frederick R.; Macfarlane, David C.; Nisse, Tony; Woodfield, Wendy; West, Richard E.

2013-01-01

In this study, the authors examined the journal "Computers & Education" to discover research trends in the articles published during 2002-2011. Research articles were analyzed to determine trends in the research methods and types of articles published, as well as the key topics published, top authors, and some of the most-cited…

Reflections on the Journal of Applied Psychology for 1997 to 2002.

PubMed

Murphy, Kevin R

2017-03-01

Major trends in articles published during my term as Editor (1997-2000) are reviewed, including the number of articles received (approximately 500-600 per year) and the types of articles published. More than half of the articles published during this period fell into six broad categories: job attitudes and affect (82 articles); individual differences and measurement (52 articles); forensic psychology (50 articles); diversity and discrimination (46 articles); research methods, design, and analysis (41 articles); and performance appraisal and performance management (41 articles). Notable articles and advances within each of these areas are described. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Mathematical modeling relevant to closed artificial ecosystems

USGS Publications Warehouse

DeAngelis, D.L.

2003-01-01

The mathematical modeling of ecosystems has contributed much to the understanding of the dynamics of such systems. Ecosystems can include not only the natural variety, but also artificial systems designed and controlled by humans. These can range from agricultural systems and activated sludge plants, down to mesocosms, microcosms, and aquaria, which may have practical or research applications. Some purposes may require the design of systems that are completely closed, as far as material cycling is concerned. In all cases, mathematical modeling can help not only to understand the dynamics of the system, but also to design methods of control to keep the system operating in desired ranges. This paper reviews mathematical modeling relevant to the simulation and control of closed or semi-closed artificial ecosystems designed for biological production and recycling in applications in space. Published by Elsevier Science Ltd on behalf of COSPAR.

Hibernation for space travel: Impact on radioprotection.

PubMed

Cerri, Matteo; Tinganelli, Walter; Negrini, Matteo; Helm, Alexander; Scifoni, Emanuele; Tommasino, Francesco; Sioli, Maximiliano; Zoccoli, Antonio; Durante, Marco

2016-11-01

Hibernation is a state of reduced metabolic activity used by some animals to survive in harsh environmental conditions. The idea of exploiting hibernation for space exploration has been proposed many years ago, but in recent years it is becoming more realistic, thanks to the introduction of specific methods to induce hibernation-like conditions (synthetic torpor) in non-hibernating animals. In addition to the expected advantages in long-term exploratory-class missions in terms of resource consumptions, aging, and psychology, hibernation may provide protection from cosmic radiation damage to the crew. Data from over half century ago in animal models suggest indeed that radiation effects are reduced during hibernation. We will review the mechanisms of increased radioprotection in hibernation, and discuss possible impact on human space exploration. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

CCR 20th Anniversary commentary: in search of cetuximab's first indication-combination therapy with irinotecan in colorectal cancer.

PubMed

Hicklin, Daniel J

2015-04-01

The research article by Prewett and colleagues, published in the May 1, 2002, issue of Clinical Cancer Research, provided important translational data that extended earlier preclinical and clinical studies with the human-murine chimeric anti-EGFR monoclonal antibody C225. Subsequent clinical trials with C225 led to the demonstration of its efficacy in combination with irinotecan and regulatory approval for the treatment of metastatic colorectal cancer. ©2015 American Association for Cancer Research.

In-Situ Biological Decontamination of an Ice Melting Probe

NASA Astrophysics Data System (ADS)

Digel, Ilya

A major concern in space and even many terrestrial missions is the forward contamination of the alien environment with microbes and biological molecules, transported on spacecraft from Earth. Furthermore, organisms and molecules can be brought to the sampling place from the surface. All this can lead to serious misinterpretations of the obtained data and more impor-tantly, could irreversibly alter the pristine nature of the extraterrestrial environments. These issues were addressed and are constantly updated in COSPAR planetary protection policy (20 October 2002; Amended 24 March 2005; 20 July 2008). The objective of our study was to investigate the efficacy of different in-situ decontamination protocols in the conditions of thermo-mechanical ice-melting. We evaluated survival rate of microorganisms on the melting probe as a function of both time and penetration depth. Special focus was made on deter-mination of the optimal concentration of chemical decontaminants (hydrogen peroxide and sodium hypochlorite) the peculiarities of their antimicrobial action at low temperatures (-80 to 0C) combined with constant dilution with melted ice and mechanical abrasion. Common, non-pathogenic microbial strains belonging to different morphological and metabolic groups (Pseudomonas, Micrococcus, Escherichia, Bacillus and others) were chosen as test objects for this study. The working part of the melting probe was first controllably contaminated by in-cubation in suspension of microbial cells. After appropriate sedimentation of microbial cells had been reached, the drilling-melting process was started using specially prepared sterile ice blocks. Every 2 minutes the samples were taken and analyzed. In the control tests, 1 mL of distilled water was injected into the penetration site at the onset of drilling. In the other tests, 1 mL of hydrogen peroxide (30Collected data suggest high efficacy of both used compounds in respect of all tested microbial groups. Typically, 99.9

VizieR Online Data Catalog: List of 1254 X-ray bursts (in't Zand+, 2017)

NASA Astrophysics Data System (ADS)

in't Zand, J. J. M.; Visser, M. E. B.; Galloway, D. K.; Chenevez, J.; Keek, L.; Kuulkers, E.; Sanchez-Fernandez, C.; Worpel, H.

2017-09-01

The list of thermonuclear X-ray bursts that RXTE detected was obtained from the Multi-INstrument Burst ARchive (MINBAR; Galloway et al. 2010, in COSPAR Meeting, Vol. 38, 38th COSPAR Scientific Assembly, 6). In addition to RXTE/PCA data, MINBAR contains the bursts detected with BeppoSAX/WFC (Jager et al., 1997A&AS..125..557J) and the still operational INTEGRAL/JEM-X (Lund et al., 2003A&A...411L.231L). The PCA list in MINBAR consists of 2288 bursts from 60 sources (i.e., this is slightly more than half the currently known burster population). Some sources only exhibited one burst in the PCA (e.g., KS 1741-293), while others had close to 400 (e.g., 4U 1636-536). (2 data files).

CORRIGENDUM: Editorial note

NASA Astrophysics Data System (ADS)

Rae, A. I. M.

2002-07-01

The first sentence of this comment should read as follows: It has been drawn to our attention that a comment published in our January issue [1] contains the statement that `the functions {1, sin2 α, cos 2α}...are clearly linearly independent...'. References [1]Figueroa-Navarro C 2002 A comment on Gluskin's note on J D Jackson's Classical Electrodynamics Eur. J. Phys. 23 L1-3

Chemical evolution of RNA under hydrothermal conditions and the role of thermal copolymers of amino acids for the prebiotic degradation and formation of RNA

NASA Technical Reports Server (NTRS)

Kawamura, K.; Nagahama, M.; Kuranoue, K.

2005-01-01

The roles of thermal copolymers of amino acids (TCAA) were studied for the prebiotic degradation of RNA. A weak catalytic ability of TCAA consisted of Glu, L-Ala, L-Val, L-Glu, L-Asp, and optionally L-His was detected for the cleavage of the ribose phosphodiester bond of a tetranucleotide (5'-dCrCdGdG) in aqueous solution at 80 degees C. The rate constants of the disappearance of 5'-dCrCdGdG were determined in aqueous solutions using different pH buffer and TCAA. The degradation rates were enhanced 1.3-3.0 times in the presence of TCAA at pH 7.5 and 8.0 at 80 degrees C, while the hydrolysis of oligoguanylate (oligo(G)) was accelerated about 1.6 times at pH 8.0. A weak inhibitory activity for the cleavage of oligo(G) was detected in the presence of 0.055 M TCAA-Std. On the other hand, our recent study on the influences of TCAA for the template-directed reaction of oligo(G) on a polycytidylic acid template showed that TCAA has an acceleration activity for the degradation of the activated nucleotide monomer and an acceleration activity for the formation of G5' ppG capped oligo(G). This series of studies suggest that efficient and selective catalytic or inhibitory activities for either the degradation or formation of RNA under hydrothermal conditions could have hardly emerged from the simple thermal condensation products of amino acids. A scenario is going to be deduced on the chemical evolution of enzymatic activities and RNA molecules concerning hydrothermal earth conditions. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

2002-2011

ERIC Educational Resources Information Center

Henrie, Curtis R.; Williams, Greg S.; West, Richard E.

2013-01-01

The authors analyzed all research articles published between 2002 and 2011 in the international journal "Instructional Science," with a goal to provide an understanding of the type of research being published in this journal, major contributing authors, and the most-cited publications of this time period. They examined research…

Space Weather - Current Capabilities, Future Requirements, and the Path to Improved Forecasting

NASA Astrophysics Data System (ADS)

Mann, Ian

2016-07-01

We present an overview of Space Weather activities and future opportunities including assessments of current status and capabilities, knowledge gaps, and future directions in relation to both observations and modeling. The review includes input from the scientific community including from SCOSTEP scientific discipline representatives (SDRs), COSPAR Main Scientific Organizers (MSOs), and SCOSTEP/VarSITI leaders. The presentation also draws on results from the recent activities related to the production of the COSPAR-ILWS Space Weather Roadmap "Understanding Space Weather to Shield Society" [Schrijver et al., Advances in Space Research 55, 2745 (2015) http://dx.doi.org/10.1016/j.asr.2015.03.023], from the activities related to the United Nations (UN) Committee on the Peaceful Uses of Outer Space (COPUOS) actions in relation to the Long-term Sustainability of Outer Space (LTS), and most recently from the newly formed and ongoing efforts of the UN COPUOS Expert Group on Space Weather.

Outstanding Science Trade Books for Students K-12: Books Published in 2002.

ERIC Educational Resources Information Center

Science and Children, 2003

2003-01-01

Provides a list of outstanding science trade books for elementary and secondary students published in 2002. Focuses on the areas of archaeology, anthropology, paleontology, biography, environment and ecology, life science, physical science, and science-related careers. Presents the selection criteria. (YDS)

Exploration of Icy Moons in the Outer Solar System: Updated Planetary Protection Requirements for Missions to Enceladus and Europa

NASA Astrophysics Data System (ADS)

Rummel, J. D.; Race, M. S.

2016-12-01

Enceladus and Europa are bodies with icy/watery environments and potential habitable conditions for life, making both of great interest in astrobiological studies of chemical evolution and /or origin of life. They are also of significant planetary protection concern for spacecraft missions because of the potential for harmful contamination during exploration. At a 2015 COSPAR colloquium in Bern Switzerland, international scientists identified an urgent need to establish planetary protection requirements for missions proposing to return samples to Earth from Saturn's moon Enceladus. Deliberations at the meeting resulted in recommended policy updates for both forward and back contamination requirements for missions to Europa and Enceladus, including missions sampling plumes originating from those bodies. These recently recommended COSPAR policy revisions and biological contamination requirements will be applied to future missions to Europa and Encealadus, particularly noticeable in those with plans for in situ life detection and sample return capabilities. Included in the COSPAR policy are requirementsto `break the chain of contact' with Europa or Enceladus, to keep pristine returned materials contained, and to complete required biohazard analyses, testing and/or sterilization upon return to Earth. Subsequent to the Bern meeting, additional discussions of Planetary Protection of Outer Solar System bodies (PPOSS) are underway in a 3-year study coordinated by the European Science Foundation and involving multiple international partners, including Japan, China and Russia, along with a US observer. This presentation will provide science and policy updates for those whose research or activities will involve icy moon missions and exploration.

From the desk of the Editor-in-Chief

NASA Astrophysics Data System (ADS)

Hei, Tom K.

2015-07-01

Life Sciences in Space Research had a prominent presence at the International Congress of Radiation Research (ICRR) meeting held in Kyoto, Japan from May 25th-29th, with seven of the eleven editors attending the meeting. A journal booth was also put up at the pre-ICRR satellite meeting on Space Radiation and Heavy Ions in Therapy (SRHITS) held a few days earlier in Osaka. Since the inception of LSSR last year, the editors and publisher have promoted the journal at a number of major conferences including COSPAR 2014 in Moscow, the annual meeting of the Radiation Research Society and the NASA Space Radiation Investigators Meeting. These efforts have increased awareness of the journal among investigators in space life sciences and related fields. The number of monthly downloads of articles from the journal website averages 2000, a respectable number for a brand new journal.

Radiation risk and human space exploration.

PubMed

Schimmerling, W; Cucinotta, F A; Wilson, J W

2003-01-01

Radiation protection is essential to enable humans to live and work safely in space. Predictions about the nature and magnitude of the risks posed by space radiation are subject to very large uncertainties. Prudent use of worst-case scenarios may impose unacceptable constraints on shielding mass for spacecraft or habitats, tours of duty of crews on Space Station, and on the radius and duration of sorties on planetary surfaces. The NASA Space Radiation Health Program has been devised to develop the knowledge required to accurately predict and to efficiently manage radiation risk. The knowledge will be acquired by means of a peer-reviewed, largely ground-based and investigator-initiated, basic science research program. The NASA Strategic Plan to accomplish these objectives in a manner consistent with the high priority assigned to the protection and health maintenance of crews will be presented. Published by Elsevier Science Ltd on behalf of COSPAR.

Deep space environments for human exploration

NASA Technical Reports Server (NTRS)

Wilson, J. W.; Clowdsley, M. S.; Cucinotta, F. A.; Tripathi, R. K.; Nealy, J. E.; De Angelis, G.

2004-01-01

Mission scenarios outside the Earth's protective magnetic shield are being studied. Included are high usage assets in the near-Earth environment for casual trips, for research, and for commercial/operational platforms, in which career exposures will be multi-mission determined over the astronaut's lifetime. The operational platforms will serve as launching points for deep space exploration missions, characterized by a single long-duration mission during the astronaut's career. The exploration beyond these operational platforms will include missions to planets, asteroids, and planetary satellites. The interplanetary environment is evaluated using convective diffusion theory. Local environments for each celestial body are modeled by using results from the most recent targeted spacecraft, and integrated into the design environments. Design scenarios are then evaluated for these missions. The underlying assumptions in arriving at the model environments and their impact on mission exposures within various shield materials will be discussed. Published by Elsevier Ltd on behalf of COSPAR.

Water extraction on Mars for an expanding human colony.

PubMed

Ralphs, M; Franz, B; Baker, T; Howe, S

2015-11-01

In-situ water extraction is necessary for an extended human presence on Mars. This study looks at the water requirements of an expanding human colony on Mars and the general systems needed to supply that water from the martian atmosphere and regolith. The proposed combination of systems in order to supply the necessary water includes a system similar to Honeybee Robotics' Mobile In-Situ Water Extractor (MISWE) that uses convection, a system similar to MISWE but that directs microwave energy down a borehole, a greenhouse or hothouse type system, and a system similar to the Mars Atmospheric Resource Recovery System (MARRS). It is demonstrated that a large water extraction system that can take advantage of large deposits of water ice at site specific locations is necessary to keep up with the demands of a growing colony. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Radiation risk and human space exploration

NASA Technical Reports Server (NTRS)

Schimmerling, W.; Cucinotta, F. A.; Wilson, J. W.

2003-01-01

Radiation protection is essential to enable humans to live and work safely in space. Predictions about the nature and magnitude of the risks posed by space radiation are subject to very large uncertainties. Prudent use of worst-case scenarios may impose unacceptable constraints on shielding mass for spacecraft or habitats, tours of duty of crews on Space Station, and on the radius and duration of sorties on planetary surfaces. The NASA Space Radiation Health Program has been devised to develop the knowledge required to accurately predict and to efficiently manage radiation risk. The knowledge will be acquired by means of a peer-reviewed, largely ground-based and investigator-initiated, basic science research program. The NASA Strategic Plan to accomplish these objectives in a manner consistent with the high priority assigned to the protection and health maintenance of crews will be presented. Published by Elsevier Science Ltd on behalf of COSPAR.

Biological filters and their use in potable water filtration systems in spaceflight conditions.

PubMed

Thornhill, Starla G; Kumar, Manish

2018-05-01

Providing drinking water to space missions such as the International Space Station (ISS) is a costly requirement for human habitation. To limit the costs of water transport, wastewater is collected and purified using a variety of physical and chemical means. To date, sand-based biofilters have been designed to function against gravity, and biofilms have been shown to form in microgravity conditions. Development of a universal silver-recycling biological filter system that is able to function in both microgravity and full gravity conditions would reduce the costs incurred in removing organic contaminants from wastewater by limiting the energy and chemical inputs required. This paper aims to propose the use of a sand-substrate biofilter to replace chemical means of water purification on manned spaceflights. Copyright © 2018 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Integrating public perspectives in sample return planning.

PubMed

Race, M S; MacGregor, D G

2000-01-01

Planning for extraterrestrial sample returns--whether from Mars or other solar system bodies--must be done in a way that integrates planetary protection concerns with the usual mission technical and scientific considerations. Understanding and addressing legitimate societal concerns about the possible risks of sample return will be a critical part of the public decision making process ahead. This paper presents the results of two studies, one with lay audiences, the other with expert microbiologists designed to gather information on attitudes and concerns about sample return risks and planetary protection. Focus group interviews with lay subjects, using generic information about Mars sample return and a preliminary environmental impact assessment, were designed to obtain an indication of how the factual content is perceived and understood by the public. A research survey of microbiologists gathered information on experts' views and attitudes about sample return, risk management approaches and space exploration risks. These findings, combined with earlier research results on risk perception, will be useful in identifying levels of concern and potential conflicts in understanding between experts and the public about sample return risks. The information will be helpful in guiding development of the environmental impact statement and also has applicability to proposals for sample return from other solar system bodies where scientific uncertainty about extraterrestrial life may persist at the time of mission planning. c2001 COSPAR Published by Elsevier Science Ltd. All rights reserved.

Detection of microlesions induced by heavy ions using liposomes filled with fluorescent dye

NASA Technical Reports Server (NTRS)

Koniarek, J. P.; Thomas, J. L.; Vazquez, M.

2004-01-01

In cells irradiation by heavy ions has been hypothesized to produce microlesions, regions of local damage. In cell membranes this damage is thought to manifest itself in the form of holes. The primary evidence for microlesions comes from morphological studies of cell membranes, but this evidence is still controversial, especially since holes also have been observed in membranes of normal, nonirradiated, cells. However, it is possible that damage not associated with histologically discernable disruptions may still occur. In order to resolve this issue, we developed a system for detecting microlesions based on liposomes filled with fluorescent dye. We hypothesized that if microlesions form in these liposomes as the result of irradiation, then the entrapped dye will leak out into the surrounding medium in a measurable way. Polypropylene vials containing suspensions of vesicles composed of either dipalmitoyl phosphatidylcholine, or a combination of egg phosphatidylcholine and cholesterol were irradiated at the Brookhaven National Laboratory using 56Fe ions at 1 GeV/amu. In several cases we obtained a significant loss of the entrapped dye above the background level. Our results suggest that holes may form in liposomes as the result of heavy ion irradiation, and that these holes are large enough to allow leakage of cell internal contents that are at least as large as a 1 nm diameter calcein molecule. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

The FLUKA code for space applications: recent developments

NASA Technical Reports Server (NTRS)

Andersen, V.; Ballarini, F.; Battistoni, G.; Campanella, M.; Carboni, M.; Cerutti, F.; Empl, A.; Fasso, A.; Ferrari, A.; Gadioli, E.;

The MELISSA pilot plant facility as as integration test-bed for advanced life support systems

NASA Technical Reports Server (NTRS)

Godia, F.; Albiol, J.; Perez, J.; Creus, N.; Cabello, F.; Montras, A.; Masot, A.; Lasseur, Ch

2004-01-01

The different advances in the Micro Ecological Life Support System Alternative project (MELISSA), fostered and coordinated by the European Space Agency, as well as in other associated technologies, are integrated and demonstrated in the MELISSA Pilot Plant laboratory. During the first period of operation, the definition of the different compartments at an individual basis has been achieved, and the complete facility is being re-designed to face a new period of integration of all these compartments. The final objective is to demonstrate the potentiality of biological systems such as MELISSA as life support systems. The facility will also serve as a test bed to study the robustness and stability of the continuous operation of a complex biological system. This includes testing of the associated instrumentation and control for a safe operation, characterization of the chemical and microbial safety of the system, as well as tracking the genetic stability of the microbial strains used. The new period is envisaged as a contribution to the further development of more complete biological life support systems for long-term manned missions, that should be better defined from the knowledge to be gained from this integration phase. This contribution summarizes the current status of the Pilot Plant and the planned steps for the new period. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Effects of heavy ions on visual function and electrophysiology of rodents: the ALTEA-MICE project

NASA Technical Reports Server (NTRS)

Sannita, W. G.; Acquaviva, M.; Ball, S. L.; Belli, F.; Bisti, S.; Bidoli, V.; Carozzo, S.; Casolino, M.; Cucinotta, F.; De Pascale, M. P.;

Gravisensing in single-celled systems: characean rhizoids and protonemata.

PubMed

Braun, M

2001-01-01

Gravitropically tip-growing cell types are attractive unicellular model systems for investigating the mechanisms and the regulation of gravitropism. Especially useful for studying the mechanisms of positive and negative gravitropic tip-growth are characean rhizoids and protonemata. They originate from the same cell type, show the same overall cell shape, cytoplasmic zonation, arrangement of actin and microtubule cytoskeleton, use statoliths for gravisensing, but show opposite gravitropism. In both cell types, actin microfilaments are complexly organized in the apical dome,where a dense spherical actin array is colocalized with spectrin-like epitopes and a unique endoplasmic reticulum aggregate, the structural center of the Spitzenkörper. The opposite gravitropic responses seem to be based on differences in the actin-organized anchorage of the Spitzenkörper and the actin-mediated transport of statoliths. In negatively gravitropic (upward bending) protonemata, the statoliths-induced drastic upward shift of the cell tip is preceded by a relocalization of dihydropyridine-binding calcium channels and of the apical calcium gradient to the upper flank (bending by bulging). Such relocalizations have not been observed in positively gravitropically responding (downward growing) rhizoids in which statoliths sedimentation is followed by differential flank growth (bending by bowing). This paper reviews the current knowledge and hypotheses on the mechanisms of the opposite gravitropic responses in characean rhizoids and protonemata. c 2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Legislation: Legislation and Regulations Affecting Libraries in 2002; Legislation and Regulations Affecting Publishing in 2002.

ERIC Educational Resources Information Center

Sheketoff, Emily; Costabile, Mary R.; Adler, Allan

2003-01-01

Reviews legislation and regulations affecting libraries and the publishing industry, including the Museum and Library Services Act; Office of Educational Research and Improvement (OERI); copyright; access to electronic government information; telecommunications and technology; electronic surveillance and privacy, including the USA Patriot Act;…

Randomized controlled drug trials on very elderly subjects: descriptive and methodological analysis of trials published between 1990 and 2002 and comparison with trials on adults.

PubMed

Le Quintrec, Jean-Laurent; Bussy, Caroline; Golmard, Jean-Louis; Hervé, Christian; Baulon, Alain; Piette, François

2005-03-01

Very elderly subjects (VES; aged 80 years or older) constitute a special population as they frequently present multiple diseases (polypathology). Results from trials on general adult populations therefore cannot be extrapolated to VES. We performed a census of randomized controlled trials (RCT) on VES published between 1990 and 2002, and carried out a descriptive and methodological analysis of these RCT/VES, comparing them with matched RCT on general adult populations (control RCT, RCT/C). We searched for RCT/VES in two international databases (EMBASE and MEDLINE) and then manually. RCT/C were matched to RCT/VES for disease area and year of publication. The methodological quality of each RCT was assessed with Chalmers' scale. We identified 84 RCT/VES, 63 of which were conclusive and 21, inconclusive. Subjects were institutionalized in 48 RCT, and community dwelling in 11 RCT (unspecified in 25 RCT). Efficacy was the main criterion in 75 RCT; tolerance in 9 RCT. Twenty-six RCT were published by geriatrics journals, and 58 by general medical journals. The RCT/VES covered most of the disease areas of geriatrics. The 84 RCT/VES had a mean methodological quality score of 0.578 +/- 0.157. The matched 84 RCT/C had a mean methodological quality score of 0.592 +/- 0.116 (p = .466). The methodological quality score of RCT/VES increased with the number of included subjects (p = .004) and the year of publication (p = .001). The methodological quality of RCT/VES is equivalent to that of RCT in general adult populations. Nevertheless, RCT/VES remain very scarce, and neglect certain diseases. RCT/VES and the inclusion of very elderly subjects in RCT on adults should be strongly encouraged.

A Revitalized USAF Culture of Innovation

DTIC Science & Technology

2013-11-01

Stephen B., “The United States Air Force and the culture of innovation 1945-1965” Air Force History and Museums Program Washington D.C. Published 2002...developing ideas that have potential. These ideas would be captured in a database similar to the Joint Lessons Learned Information System (JLISS...develop their solutions. A sabbatical program would address this need. While there is little history of sabbaticals in the military, and none

Recommendations on Coaching Strategies for Implementing Lean (Defense Acquisition Review Journal, August-November 2004)

DTIC Science & Technology

2004-01-01

Their answers are published in his book titled Lean Machines: Learning From the Leaders of The Next Industrial Revolution (Hermes, 2002; McCormack, 2002a...A. McCormack (Ed.), Lean machines—Learning from the leaders of the next industrial revolution (pp. 145–150). Annandale, VA: Publishers & Producers

Implementation of the hepatitis C guidelines in UK health care workers.

PubMed

Gibson, Kirstie; Kennedy, Ioana

2007-12-01

The UK Health Department circular HSC 2002/010 requires health care employers to test certain groups of health care workers (HCWs) for hepatitis C, without additional funding. Little is known about the consistency of implementation of such guidelines. This study audited the process, completeness and problems of implementation of circular HSC 2002/010 in acute and ambulance trusts in London and the Southeast of England. Telephone questionnaire survey of 51 National Health Service trusts between July and October 2005. The response rate was 92% (47/51). Eighty-five per cent (40/47) of the trusts reported partial or full implementation of the guidance. All compliant trusts reported testing HCWs entering exposure prone procedure specialities, although 40% (16/40) were testing more staff than specified in the guidance. Most trusts (85%) in this audit reported having implemented the guidance 3 years after publication and 90% claimed not to have needed additional funding. Implementation may be improved by greater clarity about which staff should be tested, frequency of testing and by raising HCWs awareness about hepatitis C infection and treatment. Newly published health clearance guidance addresses some of these points.

Publications - RDF 2002-1 | Alaska Division of Geological & Geophysical

Science.gov Websites

., Clautice, K.H., Flynn, R.L., Grady, J.C., Munly, W.C., and Johnson, M.R. Publication Date: Aug 2002 ., Flynn, R.L., Grady, J.C., Munly, W.C., and Johnson, M.R., 2002, Major-oxide, minor-oxide, trace-element

SETI from the moon: an invitation to COSPAR

NASA Astrophysics Data System (ADS)

Heidmann, J.

After presenting arguments for SETI (Search for ExtraTerrestrial Intelligence) work to be done well into the 21st century, and in view of the dramatic increase of blinding human-made radiofrequency interference, this author proposed that a well defined locale on the farside of the Moon - crater Saha - be preserved for the next 20-30 years not only for SETI but also for future high-sensitivity radioastronomy. The long-term programmatic issues were presented at the Lunar Exploration Symposium of the Jerusalem 1994 International Astronautical Federation Congress. The legal questions raised were delineated at the International Institute of Space Law (IISL) Colloquium of the same Jerusalem Congress. Numerous suggestions were given for an action strategy, in particular to present a proposal at a COSPAR venue. In the words of IISL Director A.A. Cocca: ``This reservation of a lunar zone for scientific activities, and its further utilization aiming at the common good of humanity, must be recognized, and constitutes a precedent.'' At the Hamburg 1995 European Geophysical Society XXth GA, we pointed out that this Saha project could offer interesting possibilities for a symbiosis with the `Science on the Moon Exobiology' teams. We also presented it at the Berlin 1996 European Space Agency/Deutsche Forschungsanstalt für Luft und Raumfahrt `International Moon Workshop' to geologists and to bioastrononomers at the Capri 1996 Bioastronomy International Astronomical Union Colloquium #161. At the 1995 IAF Congress in Oslo, the SETI Committee of the International Academy of Astronautics took action for the future benefit of humankind by setting-up a Sub-committee for `A SETI Lunar Study', chaired by the author. We hope that, in view of these initial endeavors, COSPAR may become interested in this Saha proposal and supports it.

Evaluation of the Efficacy of Communication-Based Treatments for Autism Spectrum Disorders: A Literature Review

ERIC Educational Resources Information Center

Brunner, Debra Lynn; Seung, HyeKyeung

2009-01-01

This literature review examines the present level of evidence in support of communication-based treatments for children with autism spectrum disorders. Reviews to date have reported on research published through 2002. The current article included 36 studies published between 2002 and 2007. Best available evidence is presented for seven treatment…

FY 2002 Scientific and Technical Reports, Articles, Papers, and Presentations

NASA Technical Reports Server (NTRS)

Fowler, B. A. (Compiler)

2003-01-01

This Technical Memorandum (TM) presents formal NASA technical reports, papers published in technical journals, and presentations by MSFC personnel in FY 2002. It also includes papers of MSFC contractors. The information in this TM may be of value to the scientific and engineering community in determining what information has been published and what is available.

Therapies for children with cerebral palsy: A Web of Science-based literature analysis.

PubMed

Mu, Yaping; Li, Na; Guan, Lijun; Wang, Chunnan; Shang, Shuyun; Wang, Yan

2012-11-25

To identify global research trends in three therapies for children with cerebral palsy. We performed a bibliometric analysis of studies on therapies for children with cerebral palsy from 2002 to 2011 retrieved from Web of Science. (a) peer-reviewed published articles on botulinum toxin, constraint-induced movement therapy, or acupuncture for children with cerebral palsy indexed in Web of Science; (b) original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items; and (c) publication between 2002 and 2011. (a) articles that required manual searching or telephone access; (b) documents that were not published in the public domain; and (c) a number of corrected papers from the total number of articles. (1) Number of publications on the three therapies; (2) annual publication output, distribution by journals, distribution by institution, and top-cited articles on botulinum toxin; (3) annual publication output, distribution by journal, distribution by institution, and top-cited articles on constraint-induced movement therapy; (4) annual publication, distribution by journal, distribution by institution, and top-cited articles on acupuncture. This analysis, based on Web of Science articles, identified several research trends in studies published over the past 10 years of three therapies for children with cerebral palsy. More articles on botulinum toxin for treating children with cerebral palsy were published than the articles regarding constraint-induced movement therapy or acupuncture. The numbers of publications increased over the 10-year study period. Most papers appeared in journals with a focus on neurology, such as Developmental Medicine and Child Neurology and Journal of Child Neurology. Research institutes publishing on botulinum toxin treatments for this population are mostly in the Netherlands, the United States of America, and Australia; those publishing on constraint-induced movement therapy are mostly in Australia and the United States of America; and those publishing on acupuncture are mostly in China, Sweden and the United States of America. Analysis of literature and research trends indicated that there was no one specific therapy to cure cerebral palsy. Further studies are still necessary.

Results from 15years of quality surveillance for a National Indigenous Point-of-Care Testing Program for diabetes.

PubMed

Shephard, Mark; Shephard, Anne; McAteer, Bridgit; Regnier, Tamika; Barancek, Kristina

2017-12-01

Diabetes is a major health problem for Australia's Aboriginal and Torres Strait Islander peoples. Point-of-care testing for haemoglobin A1c (HbA1c) has been the cornerstone of a long-standing program (QAAMS) to manage glycaemic control in Indigenous people with diabetes and recently, to diagnose diabetes. The QAAMS quality management framework includes monthly testing of quality control (QC) and external quality assurance (EQA) samples. Key performance indicators of quality include imprecision (coefficient of variation [CV%]) and percentage acceptable results. This paper reports on the past 15years of quality testing in QAAMS and examines the performance of HbA1c POC testing at the 6.5% cut-off recommended for diagnosis. The total number of HbA1c EQA results submitted from 2002 to 2016 was 29,093. The median imprecision for EQA testing by QAAMS device operators averaged 2.81% (SD 0.50; range 2.2 to 3.9%) from 2002 to 2016 and 2.44% (SD 0.22; range 2.2 to 2.9%) from 2009 to 2016. No significant difference was observed between the median imprecision achieved in QAAMS and by Australasian laboratories from 2002 to 2016 (p=0.05; two-tailed paired t-test) and from 2009 to 2016 (p=0.17; two-tailed paired t-test). For QC testing from 2009 to 2016, imprecision averaged 2.5% and 3.0% for the two levels of QC tested. Percentage acceptable results averaged 90% for QA testing from 2002 to 2016 and 96% for QC testing from 2009 to 2016. The DCA Vantage was able to measure a patient and an EQA sample with an HbA1c value close to 6.5% both accurately and precisely. HbA1c POC testing in QAAMS has remained analytically sound, matched the quality achieved by Australasian laboratories and met profession-derived analytical goals for 15years. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Sonya Hartnett's "Thursday's Child": Readings

ERIC Educational Resources Information Center

Armstrong, Judith; Rudd, David

2004-01-01

Sonya Hartnett's "Thursday's Child" was published in Australia by Penguin Books in 2000. Editions are available in the UK (Walker Books, 2002), the USA (Candlewick, 2002), as well as in Canada, Germany, Italy, Norway, and Denmark. In 2002, the book was awarded the "Guardian's" Children's Fiction Prize in the UK. Like Harper,…

Performance in hippocampus- and PFC-dependent cognitive domains are not concomitantly impaired in rats exposed to 20cGy of 1GeV/n (56)Fe particles.

PubMed

Britten, Richard A; Miller, Vania D; Hadley, Melissa M; Jewell, Jessica S; Macadat, Evangeline

2016-08-01

NASA is currently conducting ground based experiments to determine whether the radiation environment that astronauts will encounter on deep space missions will have an impact on their long-term health and their ability to complete the various tasks during the mission. Emerging data suggest that exposure of rodents to mission-relevant HZE radiation doses does result in the impairment of various neurocognitive processes. An essential part of mission planning is a probabilistic risk assessment process that takes into account the likely incidence and severity of a problem. To date few studies have reported the impact of space radiation in a format that is amenable to PRA, and those that have only reported data for a single cognitive process. This study has established the ability of individual male Wistar rats to conduct a hippocampus-dependent (spatial memory) task and a cortex-dependent (attentional set shifting task) 90 days after exposure to 20cGy 1GeV/n (56)Fe particles. Radiation-induced impairment of performance in one cognitive domain was not consistently associated with impaired performance in the other domain. Thus sole reliance upon a single measure of cognitive performance may substantially under-estimate the risk of cognitive impairment, and ultimately it may be necessary to establish the likelihood that mission-relevant HZE doses will impair performance in the three or four cognitive domains that NASA considers to be most critical for mission success, and build a PRA using the composite data from such studies. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Toward a global space exploration program: A stepping stone approach

NASA Astrophysics Data System (ADS)

Ehrenfreund, Pascale; McKay, Chris; Rummel, John D.; Foing, Bernard H.; Neal, Clive R.; Masson-Zwaan, Tanja; Ansdell, Megan; Peter, Nicolas; Zarnecki, John; Mackwell, Steve; Perino, Maria Antionetta; Billings, Linda; Mankins, John; Race, Margaret

2012-01-01

In response to the growing importance of space exploration in future planning, the Committee on Space Research (COSPAR) Panel on Exploration (PEX) was chartered to provide independent scientific advice to support the development of exploration programs and to safeguard the potential scientific assets of solar system objects. In this report, PEX elaborates a stepwise approach to achieve a new level of space cooperation that can help develop world-wide capabilities in space science and exploration and support a transition that will lead to a global space exploration program. The proposed stepping stones are intended to transcend cross-cultural barriers, leading to the development of technical interfaces and shared legal frameworks and fostering coordination and cooperation on a broad front. Input for this report was drawn from expertise provided by COSPAR Associates within the international community and via the contacts they maintain in various scientific entities. The report provides a summary and synthesis of science roadmaps and recommendations for planetary exploration produced by many national and international working groups, aiming to encourage and exploit synergies among similar programs. While science and technology represent the core and, often, the drivers for space exploration, several other disciplines and their stakeholders (Earth science, space law, and others) should be more robustly interlinked and involved than they have been to date. The report argues that a shared vision is crucial to this linkage, and to providing a direction that enables new countries and stakeholders to join and engage in the overall space exploration effort. Building a basic space technology capacity within a wider range of countries, ensuring new actors in space act responsibly, and increasing public awareness and engagement are concrete steps that can provide a broader interest in space exploration, worldwide, and build a solid basis for program sustainability. By engaging developing countries and emerging space nations in an international space exploration program, it will be possible to create a critical bottom-up support structure to support program continuity in the development and execution of future global space exploration frameworks. With a focus on stepping stones, COSPAR can support a global space exploration program that stimulates scientists in current and emerging spacefaring nations, and that will invite those in developing countries to participate—pursuing research aimed at answering outstanding questions about the origins and evolution of our solar system and life on Earth (and possibly elsewhere). COSPAR, in cooperation with national and international science foundations and space-related organizations, will advocate this stepping stone approach to enhance future cooperative space exploration efforts.

Nondestructive Evaluation (NDE) Technology Initiatives (NTIP). Delivery Order 0039: Statistical Comparison of Competing Material Models

DTIC Science & Technology

2003-01-01

adapted from Kass and Rafferty (1995) and Congdon (2001). Page 10 of 57 density adjusted for resin content, z, since resin contributes to the density...c.f.: Congdon , 2001). How to Download the WinBUGS Software Package BUGS was originally a statistical research project at the Medical Research...Likelihood Estimation,” July 2002, working paper to be published. 18) Congdon , Peter, Bayesian Statistical Modeling, Wiley, 2001 19) Cox, D. R. and

The giant planets and their satellites: Report on the Cospar Symposium, Ottawa, Canada, May 18-21, 1982

USGS Publications Warehouse

Kivelson, M.G.; Behannon, K.W.; Cravens, T.E.; de Pater, I.; Johnson, T.V.; Matson, D.L.; Masursky, H.; Southwood, D.J.; Vasyliunas, V.M.

1983-01-01

A Symposium on the Giant Planets and Their Satellites was presented in conjunction with the Twenty-fourth Plenary Meeting of the Committee on Space Research. This paper summarizes the talks presented and places the remaining papers of this volume in context. ?? 1983.

National transportation statistics 2002

DOT National Transportation Integrated Search

2002-12-01

Compiled and published by the Bureau of Transportation Statistics (BTS), U.S. : Department of Transportation, National Transportation Statistics 2002 presents : information on the U.S. transportation system1, including its physical components, : safe...

An active role of the amyloplasts and nuclei of root statocytes in graviperception

NASA Technical Reports Server (NTRS)

Kordyum, E.; Guikema, J.

2001-01-01

Three main phases are discerned in the gravitropic reaction: perception of a gravitational stimulus, its transduction, and fixation of the reaction resulting in bending of an organ. According to the starch-statolith hypothesis of Nemec and Haberlandt, amyloplasts in the structurally and functionally specialized graviperceptive cells (statocytes) sediment in the direction of a gravitational vector in the distal part of a cell while a nucleus is in the proximal one. If amyloplasts appear to act as gravity sensors, the receptors, which interact with sedimented amyloplasts, and next signaling are still unclear. An analysis of the structural-functional organization of cells in different root cap layers of such higher plants as pea, Arabidopsis thaliana, and Brassica rapa grown under 1 g, on the clinostats, and in microgravity, allows us to support the hypothesis that amyloplasts function as statoliths in statocytes, but they may not be only the passive statolithic mass. We propose that amyloplasts fulfill a more complex function by interacting with a receptor, which is a nucleus, in transduction of some signal to it. Gravity-induced statolith movement in certain order leads to a new functional connection between gravity susceptors--amyloplasts and a receptor--a nucleus receiving some signal presumedly of a mechanical or biochemical nature from the amyloplasts. During gravitropism, sugar signaling could induce expression of genes encoding auxin transport proteins in a nucleus giving the nucleus an intermediate role in signal trunsduction following perception. c 2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Evidence for electrotropism in some plant species.

PubMed

Gorgolewski, S; Rozej, B

2001-01-01

The ever-present global Atmospheric Electrical Field (AEF) is used by many plant species. There are many natural habitats with electrotropic plants and habitats with no AEF. The plants growing there are not electrotropic, like the plants growing under the canopies of the trees or the Arecibo radio telescope. Examples are given of different plants which belong to one or the other class, and the criteria how to distinguish them. In addition to natural habitat observations, laboratory experiments were run in search of the sensitivity of electrotropic effect to different electric field intensities. During a few years, it was established that in very strong fields (of the order of 1 MV/m) all plants respond immediately to the field. This type of reaction is due to the Coulomb forces, but electrotropism depends on electric field interaction with ions. The "reference field" (130 V/m) was always used with stronger fields in the several kV/m range which enhance plant growth rate and size similar to plant growth hormones. Surprising effects were also observed with reversed and horizontal field polarity. In conclusion electrotropic plants deprived of the electrical field do not develop as expected, as can be seen in Biosphere 2. This is an instructive example of what happens when we forget to provide the plants with this vital natural environmental factor. Electrical fields of different intensity, directions and configurations are cheap and easy to generate. c2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

CNS development under altered gravity: cerebellar glial and neuronal protein expression in rat neonates exposed to hypergravity

NASA Technical Reports Server (NTRS)

Nguon, K.; Li, G-H; Sajdel-Sulkowska, E. M.

2004-01-01

The future of space exploration depends on a solid understanding of the developmental process under microgravity, specifically in relation to the central nervous system (CNS). We have previously employed a hypergravity paradigm to assess the impact of altered gravity on the developing rat cerebellum. The present study addresses the molecular mechanisms involved in the cerebellar response to hypergravity. Specifically, the study focuses on the expression of selected glial and neuronal cerebellar proteins in rat neonates exposed to hypergravity (1.5 G) from embryonic day (E)11 to postnatal day (P)6 or P9 (the time of maximal cerebellar changes) comparing them against their expression in rat neonates developing under normal gravity. Proteins were analyzed by quantitative Western blots of cerebellar homogenates; RNA analysis was performed in the same samples using quantitative PCR. Densitometric analysis of Western blots suggested a reduction in glial (glial acidic protein, GFAP) and neuronal (neuronal cell adhesion molecule, NCAM-L1, synaptophysin) proteins, but the changes in individual cerebellar proteins in hypergravity-exposed neonates appeared both age- and gender-specific. RNA analysis suggested a reduction in GFAP and synaptophysin mRNAs on P6. These data suggest that exposure to hypergravity may interfere with the expression of selected cerebellar proteins. These changes in protein expression may be involved in mediating the effect of hypergravity on the developing rat cerebellum. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Creation of biological module for self-regulating ecological system by the way of polymerization of composite materials in free space.

PubMed

Kondyurin, A; Lauke, B; Kondyurina, I; Orba, E

2004-01-01

The large-size frame of space ship and space station can be created with the use of the technology of the polymerization of fiber-filled composites and a liquid reactionable matrix applied in free space or on the other space body when the space ship or space station will be used during a long period of time. For the polymerization of the station frame the fabric impregnated with a long-life polymer matrix (prepreg) is prepared in terrestrial conditions and, after folding, can be shipped in a compact container to orbit and kept folded on board the station. In due time the prepreg is carried out into free space and unfolded. Then a reaction of matrix polymerization starts. After reaction of polymerization the durable frame is ready for exploitation. After that, the frame can be filled out with air, the apparatus and life support systems. The technology can be used for creation of biological frame as element of self regulating ecological system, and for creation of technological frame which can be used for a production of new materials on Earth orbit in microgravity conditions and on other space bodies (Mars, Moon, asteroids) for unique high price mineral extraction. Based on such technology a future space base on Earth orbit with volume of 10(6) m3 and a crew of 100 astronauts is considered. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

[An analysis on papers published by the National Institute of Parasitic Diseases in 2002-2006].

PubMed

Zhang, Min-qi

2007-06-01

To partially evaluate the scientific and technological activities of the Institute of Parasitic Diseases, China CDC, through publication analysis. Information on the papers published in the last 5 years was collected since the renaming of the Institute in 2002. Number, category and being cited frequency of the publications were analyzed using the data of 2002 as baseline. 272 papers were published at 48 national and international periodicals during 2002-2006. The total number, the number of papers published at the core journals and at the SCI journals all increased in the year 2003-2006. Publications on research, review and report occupied 54.8%, 36.0% and 15.4% respectively, covered schistosomiasis, malaria, echinococcosis, filariasis, visceral leishmaniasis, food-borne and soil-transmitted parasitic infections, and newly emerging parasites with 44.5% and 15.4% on schistosomiasis and malaria respectively. 87.9%, 11.0% and 1.1% of the articles were published at the national, international and local journals respectively. The balance rate for the trends of papers submitted in 2002 was 6.5%, and 10.2%-15.4% in 2003-2006. 34 of the 272 papers were included in SCI journals. Retrieval through the web of knowledge revealed that 187 citations were found in the SCI papers with an average of 5.5; 6 papers were cited for more than 9 times each, occupying 27.3% of the overall citations, the highest being 84 citations. There was an unbalanced distribution of the publications among the departments of the Institute. The results indicate that the research direction and content are in line with the tasks of the Institute and with the scientific merits of disease control; the level of research is increasing and some of the publications exert certain impact at home and abroad.

A new relative referencing method for crop monitoring using chlorophyll fluorescence

NASA Technical Reports Server (NTRS)

Norikane, J.; Goto, E.; Kurata, K.; Takakura, T.

2003-01-01

The measurement of plant chlorophyll fluorescence has been used for many years as a method to monitor a plant's health status. These types of methods have been mostly relegated to the laboratory. The newly developed Relative Referencing Method allows for the measurement of chlorophyll fluorescence under artificial lighting conditions. The fluorescence signal can be determined by first taking a reference signal measurement, then a second measurement with an additional fluorescence excitation source. The first signal can then be subtracted from the second and the plant's chlorophyll fluorescence due to the second lighting source can be determined. With this simple approach, a photosynthesizing plant can be monitored to detect signs of water stress. Using this approach experiments on tomato plants have shown that it was possible to detect water stress, while the plants were continuously illuminated by fluorescent lamps. This method is a promising tool for the remote monitoring of crops grown in a CELSS-type application. Published by Elsevier Science Ltd on behalf of COSPAR.

Survey of current situation in radiation belt modeling

NASA Technical Reports Server (NTRS)

Fung, Shing F.

2004-01-01

The study of Earth's radiation belts is one of the oldest subjects in space physics. Despite the tremendous progress made in the last four decades, we still lack a complete understanding of the radiation belts in terms of their configurations, dynamics, and detailed physical accounts of their sources and sinks. The static nature of early empirical trapped radiation models, for examples, the NASA AP-8 and AE-8 models, renders those models inappropriate for predicting short-term radiation belt behaviors associated with geomagnetic storms and substorms. Due to incomplete data coverage, these models are also inaccurate at low altitudes (e.g., <1000 km) where many robotic and human space flights occur. The availability of radiation data from modern space missions and advancement in physical modeling and data management techniques have now allowed the development of new empirical and physical radiation belt models. In this paper, we will review the status of modern radiation belt modeling. Published by Elsevier Ltd on behalf of COSPAR.

The local time dependence of the anisotropic solar cosmic ray flux.

PubMed

Smart, D F; Shea, M A

2003-01-01

The distribution of the solar cosmic radiation flux over the earth is not uniform, but the result of complex phenomena involving the interplanetary magnetic field, the geomagnetic field and latitude and longitude of locations on the earth. The latitude effect relates to the geomagnetic shield; the longitude effect relates to local time. For anisotropic solar cosmic ray events the maximum particle flux is always along the interplanetary magnetic field direction, sometimes called the Archimedean spiral path from the sun to the earth. During anisotropic solar cosmic ray event, the locations on the earth viewing "sunward" into the interplanetary magnetic field direction will observe the largest flux (when adjustments are made for the magnetic latitude effect). To relate this phenomena to aircraft routes, for anisotropic solar cosmic ray events that occur during "normal quiescent" conditions, the maximum solar cosmic ray flux (and corresponding solar particle radiation dose) will be observed in the dawn quadrant, ideally at about 06 hours local time. Published by Elsevier Ltd on behalf of COSPAR.

Fitness to work of astronauts in conditions of action of the extreme emotional factors.

PubMed

Prisniakova, L M

2004-01-01

The theoretical model for the quantitative determination of influence of a level of emotional exertion on the success of human activity is presented. The learning curves of fixed words in the groups with a different level of the emotional exertion are analyzed. The obtained magnitudes of time constant T depending on a type of the emotional exertion are a quantitative measure of the emotional exertion. Time constants could also be of use for a prediction of the characteristic of fitness to work of an astronaut in conditions of extreme factors. The inverse of the sign of influencing on efficiency of activity of the man is detected. The paper offers a mathematical model of the relation between successful activity and motivations or the emotional exertion (Yerkes-Dodson law). Proposed models can serve by the theoretical basis of the quantitative characteristics of an estimation of activity of astronauts in conditions of the emotional factors at a phase of their selection. Published by Elsevier Ltd on behalf of COSPAR.

Internationalization of the American Journal of Roentgenology: 1980-2002.

PubMed

Chen, Michael Y; Jenkins, Charles B; Elster, Allen D

2003-10-01

The objective of this study was to analyze trends in the number of articles from international authors submitted to or published by the American Journal of Roentgenology (AJR) between 1980 and 2002. More than 5000 articles published by the AJR during three 3-year periods (1980-1982, 1990-1992, and 2000-2002) were categorized by country of residence of the corresponding author, type of article, subject matter and age of patients, organ system, and radiologic technique. Additionally, 6202 manuscripts submitted to the AJR (1991-1992 and 2001-2002) were used to calculate the acceptance rates for the two 2-year periods. The percentage of articles published by the AJR from international authors was 10% (158/1610) in 1980-1982, 25% (441/1788) in 1990-1992, and 37% (602/1624) in 2000-2002 (p < 0.0001). Japanese, South Korean, and German authors achieved the largest increases during the 22 years covered by our research, and Canada had the largest decrease. The increase in international articles at the AJR was accompanied by an absolute decrease in publications from authors in the United States. Nonetheless, during 2000-2002, the acceptance rate for major papers from authors in the United States was 45% and the acceptance rate for foreign authors was 31%. During 1990-1992, the acceptance rates for major papers were 33% and 27%, respectively. The contents of the AJR reflect a continually increasing number of international articles during the past two decades.

Astrobiological implications of dim light phototrophy in deep-sea red clays.

PubMed

Das, Anindita; Singh, Tanya; LokaBharathi, P A; Dhakephalkar, Prashant K; Mallik, Sweta; Kshirsagar, Pranav R; Khadge, N H; Nath, B Nagender; Bhattacharya, Satadru; Dagar, Aditya Kumar; Kaur, Prabhjot; Ray, Dwijesh; Shukla, Anil D; Fernandes, Christabelle E G; Fernandes, Sheryl O; Thomas, Tresa Remya A; S S, Mamatha; Mourya, Babu Shashikant; Meena, Ram Murti

2017-02-01

Red clays of Central Indian Basin (CIB) under influence of trace of Rodriguez Triple Junction exhibited chemoautotrophy, low temperature hydrothermal alterations and photoautotrophic potential. Seamount flank TVBC-08, hosting such signatures revealed dominance of aerobic anoxygenic phototroph Erythrobacter, with 93% of total 454 pyrosequencing tags. Subsequently, enrichments for both aerobic (Erythrobacter) and anaerobic anoxygenic phototrophs (green and purple sulphur bacteria) under red and white LED light illumination, with average irradiance 30.66Wm -2 , were attempted for three red-clay sediment cores. Successful enrichments were obtained after incubation for c.a. 120 days at 4°± 2°C and 25°± 2°C, representing ambient psychrophilic and low temperature hydrothermal alteration conditions respectively. During hydrothermal cooling, a microbial succession from anaerobic chemolithotrophy to oxygenic photoautotrophy through anaerobic/aerobic anoxygenic phototrophic microbes is indicated. Spectral absorbance patterns of the methanol extracted cell pellets showed peaks corresponding to metal sulphide precipitations, the Soret band of chlorosome absorbance by photosystem II and absence of peaks at Qy transition band. Dendritic nano-structures of metal sulphides are common in these sediments and are comparable with other sulphidic paleo-marine Martian analogues. Significant blue and redshifts have been observed for the experimental samples relative to the un-inoculated medium. These observations indicate the propensity of metal-sulphide deposits contributing to chemiluminiscence supporting the growth of phototrophs at least partially, in the otherwise dark abyss. The effects of other geothermal heat and light sources are also under further consideration. The potential of phototrophic microbial cells to exhibit Doppler shift in absorbance patterns is significant towards understanding planetary microbial habitability. Planetary desiccation could considerably influence Doppler effects and consequently spectral detection techniques exo-planetary microbial life. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Publications - NL 2002-1 | Alaska Division of Geological & Geophysical

Science.gov Websites

Visiting Alaska State Employees DGGS State of Alaska search Alaska Division of Geological & Geophysical 2002 Publisher: Alaska Division of Geological & Geophysical Surveys Ordering Info: Download below Reference DGGS Staff, and Werdon, M.B., 2002, Alaska GeoSurvey News - Geologic Investigations in the Salcha

Are Direct to Consumer Advertisements of Prescription Drugs Educational?: Comparing 1992 to 2002

ERIC Educational Resources Information Center

Curry, Timothy Jon; Jarosch, Jeff; Pacholok, Shelley

2005-01-01

We investigate the educational value of direct-to-consumer (DTC) prescription drug advertisements from 58 popular magazines published in 1992 and 2002. We find that the number of DTC prescription drug ads increased nine-fold from 1992 to 2002, while the advertisements for other health care products increased only slightly. We examine changes in…

Air and Space Expeditionary Force Crisis Action Leadership for Commanders

DTIC Science & Technology

2004-04-01

2002), 337. 2 Mark, Friedman, M.D., Everyday Crisis Management (Naperville, IL: First Decision Press, 2002), 5. 3 Stephen R. Covey, The 7 Habits of Highly Effective People (New...Berkley Publishing Group, 2002), 9. 12 Lt Col Bryan Gallagher, USAF, interviewed by author, February 2004. 13 Stephen R. Covey, The 7 Habits of Highly Effective People (New

More Analytical Tools for Fluids Management in Space

NASA Astrophysics Data System (ADS)

Weislogel, Mark

Continued advances during the 2000-2010 decade in the analysis of a class of capillary-driven flows relevant to materials processing and fluids management aboard spacecraft have been made. The class of flows addressed concern combined forced and spontaneous capillary flows in complex containers with interior edges. Such flows are commonplace in space-based fluid systems and arise from the particular container geometry and wetting properties of the system. Important applications for this work include low-g liquid fill and/or purge operations and passive fluid phase separation operations, where the container (i.e. fuel tank, water processer, etc.) geometry possesses interior edges, and where quantitative information of fluid location, transients, flow rates, and stability is critical. Examples include the storage and handling of liquid propellants and cryogens, water conditioning for life support, fluid phase-change thermal systems, materials processing in the liquid state, on-orbit biofluids processing, among others. For a growing number of important problems, closed-form expressions to transient three-dimensional flows are possible that, as design tools, replace difficult, time-consuming, and rarely performed numerical calculations. An overview of a selection of solutions in-hand is presented with example problems solved. NASA drop tower, low-g aircraft, and ISS flight ex-periment results are employed where practical to buttress the theoretical findings. The current review builds on a similar review presented at COSPAR, 2002, for the approximate decade 1990-2000.

Detection of surface temperature from LANDSAT-7/ETM+

NASA Astrophysics Data System (ADS)

Suga, Y.; Ogawa, H.; Ohno, K.; Yamada, K.

2003-12-01

Hiroshima Institute of Technology (HIT) in Japan has established a LANDSAT-7 Ground Station in cooperation with NASDA for receiving and processing the ETM+ data on March 15 th, 2000 in Japan. The authors performed a verification study on the surface temperature derived from thermal infrared band image data of LANDSAT 7/Enhanced Thematic Mapper Plus (ETM+) for the estimation of temperatures around Hiroshima city and bay area in the western part of Japan as a test site. As to the thermal infrared band, the approximate functions for converting the spectral radiance into the surface temperature are estimated by considering both typical surface temperatures measured by the simultaneous field survey with the satellite observation and the spectral radiance observed by ETM+ band 6 (10.40-12.50μm), and then the estimation of the surface temperature distribution around the test site was examined.In this study, the authors estimated the surface temperature distribution equivalent to the land cover categories around the test site for establishing a guideline of surface temperature detection by LANDSAT7/ETM+ data. As the result of comparison of the truth data and the estimated surface temperature, the correlation coefficients of the approximate function referred to the truth data are from 0.9821 to 0.9994, and the differences are observed from +0.7 to -1.5°C in summer, from +0.4 to -0.9 *C in autumn, from -1.6 to -3.4°C in winter and from +0.5 to -0.5C in spring season respectively. It is clearly found that the estimation of surface temperature based on the approximate functions for converting the spectral radiance into the surface temperature referred to the truth data is improved over the directly estimated surface temperature obtained from satellite data. Finally, the successive seasonal change of surface temperature distribution pattern of the test site is precisely detected with the temperature legend of 0 to 80'C derived from LANDSAT-7/ETM+ band 6 image data for the thermal environment monitoring. 2003 COSPAR. Published by Elsevier Ltd.

Impact of space research and technology on small countries

NASA Astrophysics Data System (ADS)

Serafimov, K. B.

Space research has generated and stimulated development in the following five ways: influence on other sciences; space technology transfer and spin-offs; rocket industry, direct use of space (communications, remote sensing, meteorology, navigation, etc.); growing interest towards education, science and creative work, increased prestige, etc. The necessity of small and developing countries to participate in space research has been recognized. Their role in international space cooperation has been pointed out. A number of problems have been presented for the small countries related to their adequate engagement in space research activities, as well as some considerations and conclusions in respect to their participation in space research, such as: creating their own `space specialization', optimal choice of participation in international projects and programmes, ensurance of financing, material and technical foundation and other possibilities; active participation in COPEOS, COSPAR, IAF and other space organizations. Some possible negative features in the space activities of small countries have been shown, and a brief review is given as an example of Bulgaria's participation in space research. Some possibilities of help to small and developing countries by COSPAR and IAF are analyzed.

Perfluoroalkyl Substances (PFASs) in Marine Mammals from the South China Sea and Their Temporal Changes 2002-2014: Concern for Alternatives of PFOS?

PubMed

Lam, James C W; Lyu, Jinling; Kwok, Karen Y; Lam, Paul K S

2016-07-05

Perfluorinated sulfonic acids (PFSAs) and perfluorinated carboxylic acids (PFCAs), as well as the replacement for the phase-out C8 PFSAs were determined in the liver samples of Indo-Pacific humpback dolphins (Sousa chinensis) and finless porpoises (Neophocaena phocaenoides) from the South China Sea between 2002 and 2014. Levels of total perfluoroalkyl substances (PFASs) in samples ranged from 136-15,300 and 30.5-2,720 ng/g dw for dolphin and porpoise, respectively. Significant increasing trends of several individual PFCAs and perfluorobutane sulfonate (PFBS) were found in cetacean samples from 2002 to 2014, whereas no significant temporal trends of ∑PFASs appeared over the sampling period. This pattern may be attributed to the increasing usage of PFCAs and C4-based PFSAs following the restriction/voluntary withdrawal of the production and use of perfluorooctane sulfonate (PFOS) related products. In addition, significantly increasing temporal shifting trends of PFOS to PFBS were observed in the dolphin liver samples. This pattern may be attributed to the substitution of PFOS by its alternative, PFBS. The highest levels of PFOS were observed in the liver samples of dolphin as compared with other marine mammal studies published since 2006, indicating high contamination of PFAS in the South China region. An assessment of relatively high concentrations of C8-based PFASs in the liver samples of cetaceans predicted that concentrations of PFOS would be expected to affect some proportion of the cetacean populations studied, based on the toxicity thresholds derived.

Update on HIPAA privacy: are you ready?

PubMed

Cole, Laura J; Fleisher, Lynn D

2003-01-01

The Health Insurance Portability and Accountability Act of 1996 (HIPAA) created new requirements for health care providers to protect the privacy and security of individually identifiable health information. Regulations to implement HIPAA's privacy provisions were published by the Department of Health and Human Services (HHS) in "final" form in December 2000 (the Privacy Rules). In March, 2002, HHS proposed modifications to the Privacy Rules, which were published on August 14, 2002. The modified final regulations differed from the 2000 regulations in a number of important respects. Most recently, on December 4, 2002, the Office of Civil Rights (OCR), which is charged with enforcement of HIPAA, published "Guidance Explaining Significant Aspects of the Privacy Rule." The Privacy Rules went into effect on April 14, 2003. This article provides a summary of the modified Privacy Rules, discusses some interesting aspects of OCR's "guidance," and highlights the requirements that are most likely to impact the practice of medical genetics.

Russian Stance in the Caucasus and the National Security Strategy of Georgia

DTIC Science & Technology

2005-06-01

12, 2005) 10 Marcel de Haas, “The Development of Russia’s Security Policy, 1992-2002,” in: Russian Military Reform 1992-2002, ed. Anne C. Aldis...positive tendencies in the world.14 12Marcel de Haas, “The Development of Russia’s Security Policy, 1992-2002,” in: Russian Military Reform 1992...Development of Russia’s Security Policy, 1992-2002,” in: Russian Military Reform 1992-2002, ed. Anne C. Aldis, Roger N. McDermott, 13- 18 (London, Portland

Goddard X-ray astronomy contributions to the IAU/COSPAR (1982)

NASA Technical Reports Server (NTRS)

Holt, S. S.; Petre, R.; Shafer, R. A.; Urry, C. M.; Mushotzky, R. F.

1982-01-01

The relation of X-ray flux to both the continuum flux in the optical and radio bands, and to the line emission properties of these objects were studied. The Einstein Observatory, because of increased sensitivity and improved angular resolution, increased substantially the number of known X-ray emitting active galactic nuclei. The Einstein imaging instruments detected morphology in AGN X-ray emission, in particular from jetlike structures in Cen-A, M87, and 3C273. The improved energy resolution and sensitivity of the spectrometers onboard the Observatory provide information on the geometry and ionization structure of the region responsible for the broad optical emission lines in a few AGN's. This information, combined with theoretical modeling and IUE and optical observations, allows the construction of a moderately detailed picture of the broad line region in these objects.

Planetary protection - assaying new methods

NASA Astrophysics Data System (ADS)

Nellen, J.; Rettberg, P.; Horneck, G.

Space age began in 1957 when the USSR launched the first satellite into earth orbit. In response to this new challenge the International Council for Science, formerly know as International Council of Scientific Unions (ICSU), established the Committee on Space Research (COSPAR) in 1958. The role of COSPAR was to channel the international scientific research in space and establish an international forum. Through COSPAR the scientific community agreed on the need for screening interplanetary probes for forward (contamination of foreign planets) and backward (contamination of earth by returned samples/probes) contamination. To prevent both forms of contamination a set of rules, as a guideline was established. Nowadays the standard implementation of the planetary protection rules is based on the experience gained during NASA's Viking project in 1975/76. Since then the evaluation-methods for microbial contamination of spacecrafts have been changed or updated just slowly. In this study the standard method of sample taking will be evaluated. New methods for examination of those samples, based on the identification of life on the molecular level, will be reviewed and checked for their feasibility as microbial detection systems. The methods will be examined for their qualitative (detection and verification of different organisms) and quantitative (detection limit and concentration verification) qualities. Amongst the methods analyzed will be i.e. real-time / PCR (poly-chain-reaction), using specific primer-sets for the amplification of highly conserved rRNA or DNA regions. Measurement of intrinsic fluorescence, i.e ATP using luciferin-luciferase reagents. The use of FAME (fatty acid methyl esters) and microchips for microbial identification purposes. The methods will be chosen to give a good overall coverage of different possible molecular markers and approaches. The most promising methods shall then be lab-tested and evaluated for their use under spacecraft assembly conditions. Since mars became one of the most sought-after planets in our solar system and will be visited by man-made probes quiet often in the near future, planetary protection is as important as never before.

Report of the December 2009 Titan Planetary Protection workshop

NASA Astrophysics Data System (ADS)

Raulin, Francois; Rummel, John; Kminek, Gerhard; Conley, Catharine; Ehrenfreund, Pascale

The status of planning for space missions to explore the outer solar system has identified the need to define the proper planetary protection categories and implementation guidelines for outer planet satellites. A COSPAR planetary protection workshop was held in Vienna in April 2009 on that subject, and a consensus was found regarding the planetary protection status of many of these objects. However, it was determined that for the planetary protection categorization of Titan further data and studies were required, to conclude whether there is only a remote (Cat. II) or significant (Cat. III) chance that contamination carried by a spacecraft could jeopardize future exploration. The main issue to be resolved is the uncertainty surrounding the communication between the surface and the potentially liquid water in the subsurface with regard to (feasible) processes and associated time frames. It was thus decided to have a planetary protection workshop fully dedicated to the case of Titan, both to focus greater expertise on the subject and to make use of additional Cassini-Huygens mission data. A two days Titan Planetary Protection workshop was thus organized at Caltech, on December 9 and 10, 2009. The meeting was sponsored by NASA and ESA, with the participation of the COSPAR Panel on Planetary Protection. It was attended by 25 participants. The goal of this workshop was to resolve the mission category for Titan (and Ganymede) and develop a consensus on the Category II (remote chance that contamination jeopardize future exploration) versus II+ /III (less remote or significant chance of contamination jeopardize future exploration) dichotomy, taking into account both the conservative nature of planetary protection policy and the physical constraints on the Titan and Ganymede systems. The outcome of this workshop will be presented and discussed during the PPP1 session of the COSPAR General Assembly meeting in Bremen. Note: all participants of the Titan PP workshop are associated to this presentation.

Bibliography on Biomass Feedstock Research: 1978-2002

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cushman, J.H.

2003-05-01

This report provides bibliographic citations for more than 1400 reports on biomass feedstock development published by Oak Ridge National Laboratory and its collaborators from 1978 through 2002. Oak Ridge National Laboratory is engaged in analysis of biomass resource supplies, research on the sustainability of feedstock resources, and research on feedstock engineering and infrastructure. From 1978 until 2002, Oak Ridge National Laboratory also provided technical leadership for the U.S. Department of Energy's Bioenergy Feedstock Development Program (BFDP), which supported research to identify and develop promising energy crops. This bibliography lists reports published by Oak Ridge National Laboratory and by its collaboratorsmore » in the BFDP, including graduate student theses and dissertations.« less

Free Open Access Meducation (FOAM): the rise of emergency medicine and critical care blogs and podcasts (2002-2013).

PubMed

Cadogan, Mike; Thoma, Brent; Chan, Teresa M; Lin, Michelle

2014-10-01

Disruptive technologies are revolutionising continuing professional development in emergency medicine and critical care (EMCC). Data on EMCC blogs and podcasts were gathered prospectively from 2002 through November 2013. During this time there was a rapid expansion of EMCC websites, from two blogs and one podcast in 2002 to 141 blogs and 42 podcasts in 2013. This paper illustrates the explosive growth of EMCC websites and provides a foundation that will anchor future research in this burgeoning field. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Cancer mortality in central Serbia.

PubMed

Markovic-Denic, Ljiljana; Cirkovic, Andia; Zivkovic, Snezana; Stanic, Danica; Skodric-Trifunovic, Vesna

2014-01-01

Cancer is the one of the leading cause of death worldwide. The aim of this study was to examine cancer mortality trends in the population of central Serbia in the period from 2002 to 2011. The descriptive epidemiological method was used. The mortality from all malignant tumors (code C00-C96 of the International Disease Classification) was registered. The source of mortality data was the published material of the Cancer Registry of Serbia. The source of population data was the census of 2002 and 2011 and the estimates for inter-census years. Non-standardized, age-adjusted and age-specific mortality rates were calculated. Age adjustment of mortality rates was performed by the direct method of standardization. Trend lines were estimated using linear regression. During 2002-2011, cancer caused about 20% of all deaths each year in central Serbia. More men (56.9%) than women (43.1%) died of cancer. The average mortality rate for men was 1.3 times higher compared to women. A significant trend of increase of the age-adjusted mortality rates was recorded both for males (p<0.001) and for females (p=0.02). Except gastric cancer, the age-adjusted mortality rates in men were significantly increased for lung cancer (p=0.02), colorectal cancer (p<0.05), prostate cancer (p=0.01) and pancreatic cancer (p=0.01). Age-adjusted mortality rates for breast cancer in females were remarkably increased (p=0.01), especially after 2007. In central Serbia during the period from 2002 to 2011, there was an increasing trend in mortality rates due to cancers in both sexes. Cancer mortality in males was 1.3-fold higher compared to females.

Comparative and International Education: A Bibliography (2002).

ERIC Educational Resources Information Center

Raby, Rosalind Latiner; Miller, Lisa, Comp.

2003-01-01

Cites 1,424 articles on comparative and international education in 319 journals published 2002. Categories: adult, rural, vocational, literacy, lifelong, and popular education; child, citizenship, human rights; comparative; curriculum, instruction, assessment; educational planning, development, and reform; gender; general; higher education;…

IDRA Newsletter, 2002.

ERIC Educational Resources Information Center

Robledo Montecel, Maria, Ed.; Goodman, Christie L., Ed.

2002-01-01

This document contains the 10 issues of the IDRA Newsletter published in 2002. The newsletter disseminates research findings, descriptions of successful programs and reforms, and other information related to equality of educational opportunity, focusing on Hispanic students, bilingual education, and Texas. Articles are: "Successful Bilingual…

Instrumentation for investigation of the depth-dose distribution by the Liulin-5 instrument of a human phantom on the Russian segment of ISS for estimation of the radiation risk during long term space flights

NASA Technical Reports Server (NTRS)

Semkova, J.; Koleva, R.; Todorova, G.; Kanchev, N.; Petrov, V.; Shurshakov, V.; Tchhernykh, I.; Kireeva, S.

2004-01-01

Described is the Liulin-5 experiment and instrumentation, developed for investigation of the space radiation doses depth distribution in a human phantom on the Russian Segment of the International Space Station (ISS). Liulin-5 experiment is a part of the international project MATROSHKA-R on ISS. The experiment MATROSHKA-R is aimed to study the depth dose distribution at the sites of critical organs of the human body, using models of human body-anthropomorphic and spherical tissue-equivalent phantoms. The aim of Liulin-5 experiment is long term (4-5 years) investigation of the radiation environment dynamics inside the spherical tissue-equivalent phantom, mounted in different places of the Russian Segment of ISS. Energy deposition spectra, linear energy transfer spectra, flux and dose rates for protons and the biologically-relevant heavy ion components of the galactic cosmic radiation will be measured simultaneously with near real time resolution at different depths of the phantom by a telescope of silicon detectors. Data obtained together with data from other active and passive dosimeters will be used to estimate the radiation risk to the crewmembers, verify the models of radiation environment in low Earth orbit, validate body transport model and correlate organ level dose to skin dose. Presented are the test results of the prototype unit. The spherical phantom will be flown on the ISS in 2004 year and Liulin-5 experiment is planned for 2005 year. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Long term stability of Oligo (dT) 25 magnetic beads for the expression analysis of Euglena gracilis for long term space projects.

PubMed

Becker, Ina; Strauch, Sebastian M; Hauslage, Jens; Lebert, Michael

2017-05-01

The unicellular freshwater flagellate Euglena gracilis has a highly developed sensory system. The cells use different stimuli such as light and gravity to orient themselves in the surrounding medium to find areas for optimal growth. Due to the ability to produce oxygen and consume carbon dioxide, Euglena is a suitable candidate for life support systems. Participation in a long-term space experiment would allow for the analysis of changes and adaptations to the new environment, and this could bring new insights into the mechanism of perception of gravity and the associated signal transduction chain. For a molecular analysis of transcription patterns, an automated system is necessary, capable of performing all steps from taking a sample, processing it and generating data. One of the developmental steps is to find long-term stable reagents and materials and test them for stability at higher-than-recommended temperature conditions during extended storage time. We investigated the usability of magnetic beads in an Euglena specific lysis buffer after addition of the RNA stabilizer Dithiothreitol over 360 days and the lysis buffer with the stabilizer alone over 455 days at the expected storage temperature of 19 °C. We can claim that the stability is not impaired at all after an incubation period of over one year. This might be an interesting result for researchers who have to work under non-standard lab conditions, as in biological or medicinal fieldwork. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Implementation of ALARA radiation protection on the ISS through polyethylene shielding augmentation of the Service Module Crew Quarters

NASA Technical Reports Server (NTRS)

Shavers, M. R.; Zapp, N.; Barber, R. E.; Wilson, J. W.; Qualls, G.; Toupes, L.; Ramsey, S.; Vinci, V.; Smith, G.; Cucinotta, F. A.

2004-01-01

With 5-7 month long duration missions at 51.6 degrees inclination in Low Earth Orbit, the ionizing radiation levels to which International Space Station (ISS) crewmembers are exposed will be the highest planned occupational exposures in the world. Even with the expectation that regulatory dose limits will not be exceeded during a single tour of duty aboard the ISS, the "as low as reasonably achievable" (ALARA) precept requires that radiological risks be minimized when possible through a dose optimization process. Judicious placement of efficient shielding materials in locations where crewmembers sleep, rest, or work is an important means for implementing ALARA for spaceflight. Polyethylene (CnHn) is a relatively inexpensive, stable, and, with a low atomic number, an effective shielding material that has been certified for use aboard the ISS. Several designs for placement of slabs or walls of polyethylene have been evaluated for radiation exposure reduction in the Crew Quarters (CQ) of the Zvezda (Star) Service Module. Optimization of shield designs relies on accurate characterization of the expected primary and secondary particle environment and modeling of the predicted radiobiological responses of critical organs and tissues. Results of the studies shown herein indicate that 20% or more reduction in equivalent dose to the CQ occupant is achievable. These results suggest that shielding design and risk analysis are necessary measures for reducing long-term radiological risks to ISS inhabitants and for meeting legal ALARA requirements. Verification of shield concepts requires results from specific designs to be compared with onboard dosimetry. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Combined exposure to protons and (56)Fe leads to overexpression of Il13 and reactivation of repetitive elements in the mouse lung.

PubMed

Nzabarushimana, Etienne; Prior, Sara; Miousse, Isabelle R; Pathak, Rupak; Allen, Antiño R; Latendresse, John; Olsen, Reid H J; Raber, Jacob; Hauer-Jensen, Martin; Nelson, Gregory A; Koturbash, Igor

2015-11-01

Interest in deep space exploration underlines the needs to investigate the effects of exposure to combined sources of space radiation. The lung is a target organ for radiation, and exposure to protons and heavy ions as radiation sources may lead to the development of degenerative disease and cancer. In this study, we evaluated the pro-fibrotic and epigenetic effects of exposure to protons (150 MeV/nucleon, 0.1 Gy) and heavy iron ions ((56)Fe, 600 MeV/nucleon, 0.5 Gy) alone or in combination (protons on Day 1 and (56)Fe on Day 2) in C57BL/6 male mice 4 weeks after irradiation. Exposure to (56)Fe, proton or in combination, did not result in histopathological changes in the murine lung. At the same time, combined exposure to protons and (56)Fe resulted in pronounced molecular alterations in comparison with either source of radiation alone. Specifically, we observed a substantial increase in the expression of cytokine Il13, loss of expression of DNA methyltransferase Dnmt1, and reactivation of LINE-1, SINE B1 retrotransposons, and major and minor satellites. Given the deleterious potential of the observed effects that may lead to development of chronic lung injury, pulmonary fibrosis, and cancer, future studies devoted to the investigation of the long-term effects of combined exposures to proton and heavy ions are clearly needed. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Growth in spaceflight hardware results in alterations to the transcriptome and proteome.

PubMed

Basu, Proma; Kruse, Colin P S; Luesse, Darron R; Wyatt, Sarah E

2017-11-01

The Biological Research in Canisters (BRIC) hardware has been used to house many biology experiments on both the Space Transport System (STS, commonly known as the space shuttle) and the International Space Station (ISS). However, microscopic examination of Arabidopsis seedlings by Johnson et al. (2015) indicated the hardware itself may affect cell morphology. The experiment herein was designed to assess the effects of the BRIC-Petri Dish Fixation Units (BRIC-PDFU) hardware on the transcriptome and proteome of Arabidopsis seedlings. To our knowledge, this is the first transcriptomic and proteomic comparison of Arabidopsis seedlings grown with and without hardware. Arabidopsis thaliana wild-type Columbia (Col-0) seeds were sterilized and bulk plated on forty-four 60 mm Petri plates, of which 22 were integrated into the BRIC-PDFU hardware and 22 were maintained in closed containers at Ohio University. Seedlings were grown for approximately 3 days, fixed with RNAlater ® and stored at -80 °C prior to RNA and protein extraction, with proteins separated into membrane and soluble fractions prior to analysis. The RNAseq analysis identified 1651 differentially expressed genes; MS/MS analysis identified 598 soluble and 589 membrane proteins differentially abundant both at p < .05. Fold enrichment analysis of gene ontology terms related to differentially expressed transcripts and proteins highlighted a variety of stress responses. Some of these genes and proteins have been previously identified in spaceflight experiments, indicating that these genes and proteins may be perturbed by both conditions. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Infrastructure for Planetary Sciences: Universal planetary database development project

NASA Astrophysics Data System (ADS)

Kasaba, Yasumasa; Capria, M. T.; Crichton, D.; Zender, J.; Beebe, R.

The International Planetary Data Alliance (IPDA), formally formed under COSPAR (Formal start: from the COSPAR 2008 at Montreal), is a joint international effort to enable global access and exchange of high quality planetary science data, and to establish archive stan-dards that make it easier to share the data across international boundaries. In 2008-2009, thanks to the many players from several agencies and institutions, we got fruitful results in 6 projects: (1) Inter-operable Planetary Data Access Protocol (PDAP) implementations [led by J. Salgado@ESA], (2) Small bodies interoperability [led by I. Shinohara@JAXA N. Hirata@U. Aizu], (3) PDAP assessment [led by Y. Yamamoto@JAXA], (4) Architecture and standards definition [led by D. Crichton@NASA], (5) Information model and data dictionary [led by S. Hughes@NASA], and (6) Venus Express Interoperability [led by N. Chanover@NMSU]. 'IPDA 2009-2010' is important, especially because the NASA/PDS system reformation is now reviewed as it develops for application at the international level. IPDA is the gate for the establishment of the future infrastructure. We are running 8 projects: (1) IPDA Assessment of PDS4 Data Standards [led by S. Hughes (NASA/JPL)], (2) IPDA Archive Guide [led by M.T. Capria (IASF/INAF) and D. Heather (ESA/PSA)], (3) IPDA Standards Identification [led by E. Rye (NASA/PDS) and G. Krishna (ISRO)], (4) Ancillary Data Standards [led by C. Acton (NASA/JPL)], (5) IPDA Registries Definition [led by D. Crichton (NASA/JPL)], (6) PDAP Specification [led by J. Salgado (ESA/PSA) and Y. Yamamoto (JAXA)], (7) In-teroperability Assessment [R. Beebe (NMSU) and D. Heather (ESA/PSA)], and (8) PDAP Geographic Information System (GIS) extension [N. Hirata (Univ. Aizu) and T. Hare (USGS: thare@usgs.gov)]. This paper presents our achievements and plans summarized in the IPDA 5th Steering Com-mittee meeting at DLR in July 2010. We are now just the gate for the establishment of the Infrastructure.

The Arizona Report, 1999-2002.

ERIC Educational Resources Information Center

Arizona Report, 2002

2002-01-01

This document contains the seven issues of "The Arizona Report" published in 1999-2002. A newsletter of the Mexican American Studies & Research Center (MASRC) at the University of Arizona, this publication reports on social, educational, health, and economic research on Mexican Americans and opportunities in higher education and…

North American Journal of Psychology, 2002.

ERIC Educational Resources Information Center

McCutcheon, Lynn E., Ed.

2002-01-01

"North American Journal of Psychology" publishes scientific papers of general interest to psychologists and other social scientists. Articles included in volume 4 issue 1 (March 2002) are: "An Interview with Kimmo Lehtonen: Music Therapy with Adolescents"; "The Relationship of Verbal-Nonverbal Incongruence to Communication Mismatches in Married…

COSPAR/PRBEM international working group activities report

NASA Astrophysics Data System (ADS)

Bourdarie, S.; Blake, B.; Cao, J. B.; Friedel, R.; Miyoshi, Y.; Panasyuk, M.; Underwood, C.

It is now clear to everybody that the current standard AE8 AP8 model for ionising particle specification in the radiation belts must be updated But such an objective is quite difficult to reach just as a reminder to develop AE8 AP8 model in the seventies was 10 persons full time for ten years It is clear that world-wide efforts must be combined because not any individual group has the human resource to perform these new models by themselves Under COSPAR umbrella an international group of expert well distributed around the world has been created to set up a common framework for everybody involved in this field Planned activities of the international group of experts are to - Define users needs - Provide guidelines for standard file format for ionising measurements - Set up guidelines to process in-situ data on a common basis - Decide in which form the new models will have to be - Centralise all progress done world-wide to advise the community - Try to organise world-wide activities as a project to ensure complementarities and more efficiencies between all efforts done Activities of this working group since its creation will be reported as well as future plans

United States, 2002 : 2002 Economic Census : Transportation : 2002 commodity flow survey

DOT National Transportation Integrated Search

2004-12-01

This report contains background information on the 2002 Commodity Flow Survey and then presents : detailed tabular results on shipment characteristics by mode of transportation, commodity, : distance shipped, and shipment weight. In Appendix A, key c...

Conventional Prompt Global Strike: Valuable Military Option or Threat to Global Stability?

DTIC Science & Technology

2005-09-01

The Strategic Rocket Forces, 1991-2002,” in Russian Military Reform : 1992- 2002, ed. Anne C. Aldis and Roger McDermott (Portland, OR: Frank Cass...Redefining the Threat and the War on Terrorism,” in Russian Military Reform 1992-2002, ed. Anne C. Aldis and Roger N. Mc Dermott (Portland, OR: Frank...

International Conference on Artificial Immune Systems (1st) ICARIS 2002, held on 9, 10, and 11 September 2002

DTIC Science & Technology

2002-03-07

Michalewicz, Eds., Evolutionary Computation 1: Basic Algorithms and Operators, Institute of Physics, Bristol (UK), 2000. [3] David A. Van Veldhuizen ...2000. [4] Carlos A. Coello Coello, David A. Van Veldhuizen , and Gary B. Lamont, Evolutionary Algorithms for Solving Multi-Objective Problems, Kluwer...Academic Publishers, 233 Spring St., New York, NY 10013, 2002. [5] David A. Van Veldhuizen , Multiobjective Evolution- ary Algorithms: Classifications

ATP-Binding Cassette Proteins: Towards a Computational View of Mechanism

NASA Astrophysics Data System (ADS)

Liao, Jielou

2004-03-01

Many large machine proteins can generate mechanical force and undergo large-scale conformational changes (LSCC) to perform varying biological tasks in living cells by utilizing ATP. Important examples include ATP-binding cassette (ABC) transporters. They are membrane proteins that couple ATP binding and hydrolysis to the translocation of substrates across membranes [1]. To interpret how the mechanical force generated by ATP binding and hydrolysis is propagated, a coarse-grained ATP-dependent harmonic network model (HNM) [2,3] is applied to the ABC protein, BtuCD. This protein machine transports vitamin B12 across membranes. The analysis shows that subunits of the protein move against each other in a concerted manner. The lowest-frequency modes of the BtuCD protein are found to link the functionally critical domains, and are suggested to be responsible for large-scale ATP-coupled conformational changes. [1] K. P. Locher, A. T. Lee and D. C. Rees. Science 296, 1091-1098 (2002). [2] Atilgan, A. R., S. R. Durell, R. L. Jernigan, M. C. Demirel, O. Keskin, and I. Bahar. Biophys. J. 80, 505-515(2002); M. M Tirion, Phys. Rev. Lett. 77, 1905-1908 (1996). [3] J. -L. Liao and D. N. Beratan, 2003, to be published.

2002 economic census : transportation : 2002 commodity flow survey : United States, 2002 : Hazardous materials

DOT National Transportation Integrated Search

2004-12-01

This report contains background information on the 2002 Commodity Flow Survey and then presents : detailed tabular results on shipment characteristics by mode of transportation, commodity, : distance shipped, and shipment weight. In Appendix A, key c...

A space radiation transport method development

NASA Technical Reports Server (NTRS)

Wilson, J. W.; Tripathi, R. K.; Qualls, G. D.; Cucinotta, F. A.; Prael, R. E.; Norbury, J. W.; Heinbockel, J. H.; Tweed, J.

2004-01-01

Improved spacecraft shield design requires early entry of radiation constraints into the design process to maximize performance and minimize costs. As a result, we have been investigating high-speed computational procedures to allow shield analysis from the preliminary design concepts to the final design. In particular, we will discuss the progress towards a full three-dimensional and computationally efficient deterministic code for which the current HZETRN evaluates the lowest-order asymptotic term. HZETRN is the first deterministic solution to the Boltzmann equation allowing field mapping within the International Space Station (ISS) in tens of minutes using standard finite element method (FEM) geometry common to engineering design practice enabling development of integrated multidisciplinary design optimization methods. A single ray trace in ISS FEM geometry requires 14 ms and severely limits application of Monte Carlo methods to such engineering models. A potential means of improving the Monte Carlo efficiency in coupling to spacecraft geometry is given in terms of re-configurable computing and could be utilized in the final design as verification of the deterministic method optimized design. Published by Elsevier Ltd on behalf of COSPAR.

Initial closed operation of the CELSS Test Facility Engineering Development Unit

NASA Technical Reports Server (NTRS)

Kliss, M.; Blackwell, C.; Zografos, A.; Drews, M.; MacElroy, R.; McKenna, R.; Heyenga, A. G.

2003-01-01

As part of the NASA Advanced Life Support Flight Program, a Controlled Ecological Life Support System (CELSS) Test Facility Engineering Development Unit has been constructed and is undergoing initial operational testing at NASA Ames Research Center. The Engineering Development Unit (EDU) is a tightly closed, stringently controlled, ground-based testbed which provides a broad range of environmental conditions under which a variety of CELSS higher plant crops can be grown. Although the EDU was developed primarily to provide near-term engineering data and a realistic determination of the subsystem and system requirements necessary for the fabrication of a comparable flight unit, the EDU has also provided a means to evaluate plant crop productivity and physiology under controlled conditions. This paper describes the initial closed operational testing of the EDU, with emphasis on the hardware performance capabilities. Measured performance data during a 28-day closed operation period are compared with the specified functional requirements, and an example of inferring crop growth parameters from the test data is presented. Plans for future science and technology testing are also discussed. Published by Elsevier Science Ltd on behalf of COSPAR.

Alterations in the heart rate and activity rhythms of three orbital astronauts on a space mission.

PubMed

Liu, Zhizhen; Wan, Yufeng; Zhang, Lin; Tian, Yu; Lv, Ke; Li, Yinghui; Wang, Chunhui; Chen, Xiaoping; Chen, Shanguang; Guo, Jinhu

2015-01-01

Environmental factors in space are dramatically different from those on Earth. The spaceflight environment has been known to influence human physiology and behavior on orbital missions. In this study, we investigated alterations in the diurnal rhythms of activity and heart rate of three Chinese astronauts on a space mission. An analysis of the heart rate data showed a significant decrease in heart rate amplitudes during flight in all three subjects. The heart rate amplitudes of all the three astronauts were significantly dampened during flight, and the minimum as well as the maximum value of heart rate increased after flight. A phase shift in heart rate was observed in one of the three astronauts after flight. These results demonstrate the influence of spaceflight on heart physiology and function. In addition, a significant decrease in body trunk activity and rhythmicity occurred during flight, demonstrating that the spaceflight environment disturbs motion adaptation and diurnal activity rhythms. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Fluorescent minerals--A potential source of UV protection and visible light for the growth of green algae and cyanobacteria in extreme cosmic environments.

PubMed

Omairi, Tareq; Wainwright, Milton

2015-07-01

We propose that green algae (Chlorella variabilis and Dunaliella tertiolecta) and cyanobacteria (Synechococcus elongatus and Nostoc commune) can grow inside fluorescent rock minerals which convert damaging UV light to visible light, thereby allowing these organisms to survive and thrive in UV-rich environments without (or with limited) visible light, which would otherwise be inimical to them. The four microorganisms were incubated inside fluorescent rocks composed of fluorite, calcite and pyrite. The resultant growth was then measured following exposure to UV radiation, with the use of optical density and measurement of chlorophyll concentration. Results show that the microorganisms were shielded from harmful UV in these semi-transparent rocks, while at the same time benefiting from the fact that the minerals converted UV to visible light; this have been shown by a statistically significant increase in their growth, which although lower than when the cells were incubated in sunlight, was significantly higher than in controls incubated in the dark. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Simulated sudden increase in geomagnetic activity and its effect on heart rate variability: Experimental verification of correlation studies.

PubMed

Caswell, Joseph M; Singh, Manraj; Persinger, Michael A

2016-08-01

Previous research investigating the potential influence of geomagnetic factors on human cardiovascular state has tended to converge upon similar inferences although the results remain relatively controversial. Furthermore, previous findings have remained essentially correlational without accompanying experimental verification. An exception to this was noted for human brain activity in a previous study employing experimental simulation of sudden geomagnetic impulses in order to assess correlational results that had demonstrated a relationship between geomagnetic perturbations and neuroelectrical parameters. The present study employed the same equipment in a similar procedure in order to validate previous findings of a geomagnetic-cardiovascular dynamic with electrocardiography and heart rate variability measures. Results indicated that potential magnetic field effects on frequency components of heart rate variability tended to overlap with previous correlational studies where low frequency power and the ratio between low and high frequency components of heart rate variability appeared affected. In the present study, a significant increase in these particular parameters was noted during geomagnetic simulation compared to baseline recordings. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Education Policy Analysis Archives, 2002: Numbers 26-50.

ERIC Educational Resources Information Center

Glass, Gene V., Ed.

This document consists of articles 26 through 50 published in the electronic journal "Education Policy Analysis Archives" for the year 2002: (26) "Home Schooling in the United States: Trends and Characteristics" (Kurt J. Bauman); (27) "Mentoring Narratives ON-LINE: Teaching the Principalship" (Alison I. Griffith and Svitlana Taraban); (28) "Elm…

Education Policy Analysis Archives, 2002: Numbers 1-25.

ERIC Educational Resources Information Center

Glass, Gene V., Ed.

2002-01-01

This document consists of articles 1 through 25 published in the electronic journal Education Policy Analysis Archives for the year 2002: (1) Testing and Diversity in Postsecondary Education: The Case of California (Daniel Koretz, Michael Russell, Chingwei David Shin, Cathy Horn, and Kelly Shasby); (2) State-Mandated Testing and Teachers Beliefs…

Practical Assessment, Research and Evaluation, 2002-2003.

ERIC Educational Resources Information Center

Rudner, Lawrence M., Ed.; Schaefer, William D., Ed.

2000-01-01

This document consists of the first 10 articles of volume 8 of the electronic journal "Practical Assessment, Research & Evaluation" published in 2002-2003: (1) "Using Electronic Surveys: Advice from Survey Professionals" (David M. Shannon, Todd E. Johnson, Shelby Searcy, and Alan Lott); (2) "Four Assumptions of Multiple Regression That Researchers…

Publication rate for funded studies from a major UK health research funder: a cohort study

PubMed Central

Turner, S; Wright, D; Maeso, R; Cook, A; Milne, R

2013-01-01

Objectives This study aimed to investigate what percentage of National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme-funded projects have published their final reports in the programme's journal HTA and to explore reasons for non-publication. Design Retrospective cohort study. Setting Failure to publish findings from research is a significant area of research waste. It has previously been suggested that potentially over 50% of studies funded are never published. Participants All NIHR HTA projects with a planned submission date for their final report for publication in the journal series on or before 9 December 2011 were included. Primary and secondary outcome measures The projects were classified according to the type of research, whether they had been published or not; if not yet published, whether they would be published in the future or not. The reasons for non-publication were investigated. Results 628 projects were included: 582 (92.7%) had published a monograph; 19 (3%) were expected to publish a monograph; 13 (2.1%) were discontinued studies and would not publish; 12 (1.9%) submitted a report which did not lead to a publication as a monograph; and two (0.3%) did not submit a report. Overall, 95.7% of HTA studies either have published or will publish a monograph: 94% for those commissioned in 2002 or before and 98% for those commissioned after 2002. Of the 27 projects for which there will be no report, the majority (21) were commissioned in 2002 or before. Reasons why projects failed to complete included failure to recruit; issues concerning the organisation where the research was taking place; drug licensing issues; staffing issues; and access to data. Conclusions The percentage of HTA projects for which a monograph is published is high. The advantages of funding organisations requiring publication in their own journal include avoidance of publication bias and research waste. PMID:23645914

Gravitaxis and graviperception in flagellates.

PubMed

Hader, D-P; Lebert, M; Richter, P; Ntefidou, M

2003-01-01

There is strong evidence that gravitactic orientation in flagellates and ciliates is mediated by an active physiological gravireceptor rather than by passive alignment of the cells in the water column. In flagellates the threshold for graviorientation was found to be at 0.12 x g on a slow rotating centrifuge during the IML-2 mission on the Shuttle Columbia and a subsequent parabolic rocket flight (TEXUS). During the IML-2 mission no adaptation to microgravity was observed over the duration of the space flight, while gravitaxis was lost in a terrestrial closed environmental system over the period of almost two years. Sedimenting statoliths are not likely to be involved in graviperception because of the small size of the cells and their rotation around the longitudinal axis during forward locomotion. Instead the whole cytoplasmic content of the cell, being heavier than the surrounding aqueous medium (1.05 g/ml), exerts a pressure on the lower membrane. This force activates stretch-sensitive calcium specific ion channels which can be inhibited by the addition of gadolinium which therefore abolishes gravitaxis. The channels seem to mainly allow calcium ions to pass since gravitaxis is blocked by the addition of the calcium ionophore A23187 and by vanadate which blocks the Ca-ATPase in the cytoplasmic membrane. Recently, a gene for a mechanosensitive channel, originally sequenced for Saccharomyces, was identified in Euglena by PCR. The increase in intracellular free calcium during reorientation can be visualized by the fluorophore Calcium Crimson using laser excitation and image intensification. This result was confirmed during recent parabolic flights. The gated calcium changes the membrane potential across the membrane which may be the trigger for the reorientation of the flagellum. cAMP plays a role as a secondary messenger. Photosynthetic flagellates are suitable candidates for life support systems since they absorb CO2 and produce oxygen. Preliminary experiments are discussed. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Preface: New challenges for planetary protection

NASA Astrophysics Data System (ADS)

Kminek, Gerhard

2016-05-01

Planetary protection as a discipline goes back to the advent of the space age and the formation of the Committee on Space Research (COSPAR). Planetary protection constraints are in place to ensure that scientific investigations related to the search for extraterrestrial life are not compromised and that the Earth is protected from the potential hazard posed by extraterrestrial matter carried by a spacecraft returning from an interplanetary mission.

Massey Award Given to Harvey Tananbaum

NASA Astrophysics Data System (ADS)

2010-06-01

Dr. Harvey Tananbaum, director of the Chandra X-ray Center, has been selected as the recipient of the 2010 Massey Award for his career accomplishments in high-energy astrophysics in space. The Massey Award is given by the Royal Society of London and the Committee of Space Research (COSPAR) in memory of Sir Harrie Massey, past Physical Secretary of the Society and member of the COSPAR Bureau. The prestigious award recognizes outstanding contributions to the development of space research in which a leadership role is of particular importance. Dr. Harvey Tananbaum began his career at American Science and Engineering and has been an astrophysicist at the Smithsonian Astrophysical Observatory since 1973. He was involved with pioneering X-ray astronomy missions including UHURU and the Einstein Observatory. Beginning in 1976, Dr. Tananbaum, along with Nobel Prize winner Dr. Riccardo Giacconi, led the team that proposed to NASA to study and design a large X-ray telescope. This project was launched 23 years later in 1999 as the Chandra X-ray Observatory, becoming NASA's flagship X-ray telescope. Dr. Tananbaum has served as the director of the Chandra X-ray Center since 1991. Dr. Tananbaum has received numerous awards from NASA as well as from other agencies and institutions, including the American Astronomical Society's Bruno Rossi Award in 2004 along with Chandra Project Scientist Martin Weisskopf. He is a fellow of the American Association for the Advancement of Science, and in 2005 was elected as a member of the United States National Academy of Science. The presentation of the Massey Award, along with the gold medal that accompanies it, will be made at the upcoming 2010 COSPAR meeting in Bremen, Germany in July. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program for NASA's Science Mission Directorate in Washington. The Smithsonian Astrophysical Observatory controls Chandra's science and flight operations from Cambridge, Mass. A complete list of previous award recipients may be found at: http://cosparhq.cnes.fr/Awards/awards.htm More information on Chandra can be found at: http://chandra.harvard.edu and http://chandra.nasa.gov

Water resources data, Arkansas, 2002

USGS Publications Warehouse

Brossett, T.H.; Evans, D.A.

2003-01-01

Water resources data for the 2002 water year for Arkansas consist of records of discharge and water quality (physical measurements and chemical concentrations) of streams, water quality of lakes, and groundwater levels and ground-water quality. Data from selected sites in Missouri and Oklahoma also are included. This report contains daily discharge records for 108 surface-water gaging stations and 87 peak-discharge partial-record stations, water-quality data for 65 surface-water stations and 5 wells, and water levels for 15 observation wells. Additional water data were collected at various sites, not part of the systematic data-collection program, and are published as miscellaneous measurements. Note: Historically, this report has been published as a paper report. Beginning with the 2002 water year report, these reports will be available from the World Wide Web at http://ar.water.usgs.gov.

Use of Subjective Global Assessment, Patient-Generated Subjective Global Assessment and Nutritional Risk Screening 2002 to evaluate the nutritional status of non-critically ill patients on parenteral nutrition.

PubMed

Badia-Tahull, M B; Cobo-Sacristán, S; Leiva-Badosa, E; Miquel-Zurita, M E; Méndez-Cabalerio, N; Jódar-Masanés, R; Llop-Talaverón, J

2014-02-01

To evaluate the nutritional status of non-critically ill digestive surgery patients at the moment of parenteral nutrition initiation using three different nutritional test tools and to study their correlation. To study the association between the tests and the clinical and laboratory parameters used in the follow-up of PN treatment. Prospective study over 4 months. Anthropometric and clinical variables were recorded. Results of Subjective Global Assessment; Patient-Generated Subjective Global Assessment; and Nutritional Risk Screening 2002 were compared applying kappa test. Relationship between the clinical and laboratory parameters with Subjective Global Assessment was studied by multinominal regression and with the other two tests by multiple linear regression models. Age and sex were included as adjustment variables. Malnutrition in 45 studied patients varied from 51% to 57%. Subjective Global Assessment correlated well with Patient-Generated Subjective Global Assessment and Nutritional Risk Screening 2002 (κ = 0531 p = 0.000). The test with the greatest correlation with the clinical and analytical variables was the Nutritional Risk Screening 2002. Worse nutritional state in this test was associated with worse results in albumin (B = -0.087; CI = -0.169/-0.005], prealbumin (B = -0.005; CI = [-0.011/-0.001]), C-reactive protein (B = 0.006;CI = [0.001/ 0.011]) and leukocytes (B = 0.134; CI = [0.031/0.237]) at the en of parenteral nutrition treatment. Half of the digestive surgery patients were at malnutritional risk at the moment of initiating parenteral nutrition. Nutritional Risk Screening 2002 was the test with best association with the parameters used in the clinical follow-up of parenteral nutrition treated patients. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Family Child Care Licensing Study, 2002.

ERIC Educational Resources Information Center

Children's Foundation, Washington, DC.

This report presents the findings of the 2002 national survey of state child care regulatory agencies to update and expand family child care regulatory information published in the 2001 study. Data on small family child care homes and group or large family child care homes are organized into the following 23 categories: (1) number of regulated…

Aerobic Capacities of Early College High School Students

ERIC Educational Resources Information Center

Loflin, Jerry W.

2014-01-01

The Early College High School Initiative (ECHSI) was introduced in 2002. Since 2002, limited data, especially student physical activity data, have been published pertaining to the ECHSI. The purpose of this study was to examine the aerobic capacities of early college students and compare them to state and national averages. Early college students…

Twentieth Century Moon: The Evolution of Lunar Science, 1955 - 2002

NASA Technical Reports Server (NTRS)

Templeton, T. C.; Kinney, A. L.

2008-01-01

Here we discuss thc bibliographic record of Lunar Science as published in refereed journals from 1955 to 2002. New tools in bibliometrics, i.e. the study of publications and citations, reveal the structure of this scientific field by measuring and visualizing connections between published papers. This approach is especially powerful when applied to a well defined field such as Lunar Science, which is strongly affected by policy and the actions resulting from policy, most obviously gathering samples from the Moon. This poster presents some results obtained by processing a dataset of lunar science bibliographic records through a bibliographic visualization program.

Effects of CO2 concentration and light intensity on photosynthesis of a rootless submerged plant, Ceratophyllum demersum L., used for aquatic food production in bioregenerative life support systems

NASA Technical Reports Server (NTRS)

Kitaya, Y.; Okayama, T.; Murakami, K.; Takeuchi, T.

2003-01-01

In addition to green microalgae, aquatic higher plants are likely to play an important role in aquatic food production modules in bioregenerative systems for producing feed for fish, converting CO2 to O2 and remedying water quality. In the present study, the effects of culture conditions on the net photosynthetic rate of a rootless submerged plant, Ceratophyllum demersum L., was investigated to determine the optimum culture conditions for maximal function of plants in food production modules including both aquatic plant culture and fish culture systems. The net photosynthetic rate in plants was determined by the increase in dissolved O2 concentrations in a closed vessel containing a plantlet and water. The water in the vessel was aerated sufficiently with a gas containing a known concentration of CO2 gas mixed with N2 gas before closing the vessel. The CO2 concentrations in the aerating gas ranged from 0.3 to 10 mmol mol-1. Photosynthetic photon flux density (PPFD) in the vessel ranged from 0 (dark) to 1.0 mmol m-2 s-1, which was controlled with a metal halide lamp. Temperature was kept at 28 degrees C. The net photosynthetic rate increased with increasing PPFD levels and was saturated at 0.2 and 0.5 mmol m-2 s-1 PPFD under CO2 levels of 1.0 and 3.0 mmol mol-1, respectively. The net photosynthetic rate increased with increasing CO2 levels from 0.3 to 3.0 mmol mol-1 showing the maximum value, 75 nmol O2 gDW-1 s-1, at 2-3 mmol mol-1 CO2 and gradually decreased with increasing CO2 levels from 3.0 to 10 mmol mol-1. The results demonstrate that C. demersum could be an efficient CO2 to O2 converter under a 2.0 mmol mol-1 CO2 level and relatively low PPFD levels in aquatic food production modules. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Bibliometric analysis of original molecular biology research in anaesthesia.

PubMed

Schreiber, K; Girard, T; Kindler, C H

2004-10-01

Molecular biology has expanded the horizons of anaesthesia during the last 20 years and has led to an increase of basic science articles that are published in the specialised anaesthetic journals or originate in anaesthetic institutions. We searched for and analysed the specific features, such as year of publication, publishing journal, and country of origin, of all such molecular biology articles stored in the MEDLINE database during the period 1986-2002. We identified 1265 original articles that used molecular biology techniques; 223 (18%) of these articles were published in anaesthetic journals and 1042 (82%) articles in 556 other biomedical journals. While in the late 1980s only a few molecular biology articles were published each year by anaesthetic institutions, worldwide this number reached approximately 200 basic science articles by the end of 2002. The USA clearly dominates the field of anaesthesia with respect to molecular biology research with 839 (66%) such articles.

Ozone reference models for the middle atmosphere

NASA Technical Reports Server (NTRS)

Keating, G. M.; Pitts, M. C.; Young, D. F.

1990-01-01

Data on monthly latitudinal variations in middle-atmosphere vertical ozone profiles are presented, based on extensive Nimbus-7, AE-2, and SME satellite measurements from the period 1978-1982. The coverage of the data sets, the characteristics of the sensors, and the analysis techniques applied are described, and the results are compiled in tables and graphs. These ozone data are intended to supplement the models of the 1986 COSPAR International Reference Atmosphere.

French space program: report to Cospar

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1975-01-01

Programs and results obtained are reviewed for all French laboratories working in areas of research related to space. Main topics include lunar specimen studies; spectroscopic planetology; space radiation; ionospheric and magnetospherics; aeronomy; meteorology, comprising the Meteosat program and the Eole experiment and earth resources investigations; geodesy; and geodynamics-research covering space biology and exobiology is also discussed. French satellites and sounding rockets are listed, as well as French experiments onboard foreign spacecraft. (GRA)

The COSPAR Capacity Building Initiative - past, present, future, and highlights

NASA Astrophysics Data System (ADS)

Gabriel, Carlos; Mendez, Mariano; D'Amicis, Raffaella; Santolik, Ondrej; Mathieu, Pierre-Philippe; Smith, Randall

At the time of the COSPAR General Assembly in Moscow, the 21st workshop of the Programme for Capacity Building will have taken place. We have started in 2001 with the aim of: i) increasing the knowledge and use of public archives of space data in developing countries, ii) providing highly-practical instruction in the use of these archives and the associated publicly-available software, and iii) fostering personal links between participants and the experienced scientists who lecture during the workshops and supervise the projects carried on by the students. Workshops in many space disciplines have been successfully held so far (X-ray, Gamma-ray and Space Optical and UV Astronomy, Magnetospheric Physics, Space Oceanography, Remote Sensing and Planetary Science) in thirteen countries (Argentina, Brazil, China, Egypt, India, Indonesia, Malaysia, Morocco, Romania, Russia, South Africa, Thailand and Uruguay). An associated Fellowship Programme is helping former participants of these workshops to build on skills gained at them. We will summarize the past and discuss the present and future of the Programme, including highlights like the most recent one: the identification of a transient magnetar (the 9th object of this class so far discovered) in the vicinity of a supernova by one of our students, during the CB workshop on high-energy Astrophysics in Xuyi, China, in September 2013.

Preface: The International Reference Ionosphere (IRI) at equatorial latitudes

NASA Astrophysics Data System (ADS)

Reinisch, Bodo; Bilitza, Dieter

2017-07-01

This issue of Advances in Space Research includes papers that report and discuss improvements of the International Reference Ionosphere (IRI). IRI is the international standard for the representation of the plasma in Earth's ionosphere and recognized as such by the Committee on Space Research (COSPAR), the International Union of Radio Science (URSI), the International Telecommunication Union (ITU), and the International Standardization Organization (ISO). As requested, particularly by COSPAR and URSI, IRI is an empirical model relying on most of the available and reliable ground and space observations of the ionosphere. As new data become available and as older data sources are fully exploited the IRI model undergoes improvement cycles to stay as close to the existing data record as possible. The latest episode of this process is documented in the papers included in this issue using data from the worldwide network of ionosondes, from a few of the incoherent scatter radars, from the Alouette and ISIS topside sounders, and from the Global Navigation Satellite Systems (GNSS). The focus of this issue is on the equatorial and low latitude region that is of special importance for ionospheric physics because it includes the largest densities and steep density gradients in the double hump latitudinal structure, the Equatorial Ionization Anomaly (EIA), which is characteristic for this region.

Extraterrestrial organic chemistry: from the interstellar medium to the origins of life. Part 2: complex organic chemistry in the environment of planets and satellites.

PubMed

Raulin, F; Kobayashi, K

2001-01-01

During COSPAR'00 in Warsaw, Poland, in the frame of Sub-Commission F.3 events (Planetary Biology and Origins of Life), part of COSPAR Commission F (Life Sciences as Related to Space), and Commission B events (Space Studies of the Earth-Moon System, Planets, and Small Bodies of the Solar System) a large joint symposium (F.3.4/B0.8) was held on extraterrestrial organic chemistry. Part 2 of this symposium was devoted to complex organic chemistry in the environment of planets and satellites. The aim of this event was to cover and review new data which have been recently obtained and to give new insights on data which are expected in the near future to increase our knowledge of the complex organic chemistry occurring in several planets and satellites of the Solar System, outside the earth, and their implications for exobiology and life in the universe. The event was composed of two main parts. The first part was mainly devoted to the inner planets and Europa and the search for signatures of life or organics in those environments. The second part was related to the study of the outer solar system.

Planetary protection program for Mars 94/96 mission.

PubMed

Rogovski, G; Bogomolov, V; Ivanov, M; Runavot, J; Debus, A; Victorov, A; Darbord, J C

1996-01-01

Mars surface in-situ exploration started in 1975 with the American VIKING mission. Two probes landed on the northern hemisphere and provided, for the first time, detailed information on the martian terrain, atmosphere and meteorology. The current goal is to undertake larger surface investigations and many projects are being planned by the major Space Agencies with this objective. Among these projects, the Mars 94/96 mission will make a major contributor toward generating significant information about the martian surface on a large scale. Since the beginning of the Solar System exploration, planets where life could exist have been subject to planetary protection requirements. Those requirements accord with the COSPAR Policy and have two main goals: the protection of the planetary environment from influence or contamination by terrestrial microorganisms, the protection of life science, and particularly of life detection experiments searching extra-terrestrial life, and not life carried by probes and spacecrafts. As the conditions for life and survival for terrestrial microorganisms in the Mars environment became known, COSPAR recommendations were updated. This paper will describe the decontamination requirements which will be applied for the MARS 94/96 mission, the techniques and the procedures which are and will be used to realize and control the decontamination of probes and spacecrafts.

Traffic crash statistics report, 2002

DOT National Transportation Integrated Search

2003-10-29

In 2002, Florida continued to see improvements in traffi c safety. Statewide, the number of : traffi c crashes reported and investigated was down 2.2 percent from 2001. Alcohol-related fatalities, : as a percent of total fatalities, decreased by 1.2 ...

Composition and physical properties of starch in microgravity-grown plants.

PubMed

Kuznetsov, O A; Brown, C S; Levine, H G; Piastuch, W C; Sanwo-Lewandowski, M M; Hasenstein, K H

2001-01-01

The effect of spaceflight on starch development in soybean (Glycine max L., BRIC-03) and potato (Solanum tuberosum, Astroculture-05) was compared with ground controls by biophysical and biochemical measurements. Starch grains from plants from both flights were on average 20-50% smaller in diameter than ground controls. The ratio delta X/delta rho (delta X --difference of magnetic susceptibilities, delta rho--difference of densities between starch and water) of starch grains was ca. 15% and 4% higher for space-grown soybean cotyledons and potato tubers, respectively, than in corresponding ground controls. Since the densities of particles were similar for all samples (1.36 to 1.38 g/cm3), the observed difference in delta X/delta rho was due to different magnetic susceptibilities and indicates modified composition of starch grains. In starch preparations from soybean cotyledons (BRIC-03) subjected to controlled enzymatic degradation with alpha-amylase for 24 hours, 77 +/- 6% of the starch from the flight cotyledons was degraded compared to 58 +/- 12% in ground controls. The amylose content in starch was also higher in space-grown tissues. The good correlation between the amylose content and delta X/delta rho suggests, that the magnetic susceptibility of starch grains is related to their amylose content. Since the seedlings from the BRIC-03 experiment showed elevated post-flight ethylene levels, material from another flight experiment (GENEX) which had normal levels of ethylene was examined and showed no difference to ground controls in size distribution, density, delta X/delta rho and amylose content. Therefore the role of ethylene appears to be more important for changes in starch metabolism than microgravity. c2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Simulations of an accelerator-based shielding experiment using the particle and heavy-ion transport code system PHITS.

PubMed

Sato, T; Sihver, L; Iwase, H; Nakashima, H; Niita, K

2005-01-01

In order to estimate the biological effects of HZE particles, an accurate knowledge of the physics of interaction of HZE particles is necessary. Since the heavy ion transport problem is a complex one, there is a need for both experimental and theoretical studies to develop accurate transport models. RIST and JAERI (Japan), GSI (Germany) and Chalmers (Sweden) are therefore currently developing and bench marking the General-Purpose Particle and Heavy-Ion Transport code System (PHITS), which is based on the NMTC and MCNP for nucleon/meson and neutron transport respectively, and the JAM hadron cascade model. PHITS uses JAERI Quantum Molecular Dynamics (JQMD) and the Generalized Evaporation Model (GEM) for calculations of fission and evaporation processes, a model developed at NASA Langley for calculation of total reaction cross sections, and the SPAR model for stopping power calculations. The future development of PHITS includes better parameterization in the JQMD model used for the nucleus-nucleus reactions, and improvement of the models used for calculating total reaction cross sections, and addition of routines for calculating elastic scattering of heavy ions, and inclusion of radioactivity and burn up processes. As a part of an extensive bench marking of PHITS, we have compared energy spectra of secondary neutrons created by reactions of HZE particles with different targets, with thicknesses ranging from <1 to 200 cm. We have also compared simulated and measured spatial, fluence and depth-dose distributions from different high energy heavy ion reactions. In this paper, we report simulations of an accelerator-based shielding experiment, in which a beam of 1 GeV/n Fe-ions has passed through thin slabs of polyethylene, Al, and Pb at an acceptance angle up to 4 degrees. c2005 Published by Elsevier Ltd on behalf of COSPAR.

Composition and physical properties of starch in microgravity-grown plants

NASA Technical Reports Server (NTRS)

Kuznetsov, O. A.; Brown, C. S.; Levine, H. G.; Piastuch, W. C.; Sanwo-Lewandowski, M. M.; Hasenstein, K. H.; Sager, J. C. (Principal Investigator)

2001-01-01

The effect of spaceflight on starch development in soybean (Glycine max L., BRIC-03) and potato (Solanum tuberosum, Astroculture-05) was compared with ground controls by biophysical and biochemical measurements. Starch grains from plants from both flights were on average 20-50% smaller in diameter than ground controls. The ratio delta X/delta rho (delta X --difference of magnetic susceptibilities, delta rho--difference of densities between starch and water) of starch grains was ca. 15% and 4% higher for space-grown soybean cotyledons and potato tubers, respectively, than in corresponding ground controls. Since the densities of particles were similar for all samples (1.36 to 1.38 g/cm3), the observed difference in delta X/delta rho was due to different magnetic susceptibilities and indicates modified composition of starch grains. In starch preparations from soybean cotyledons (BRIC-03) subjected to controlled enzymatic degradation with alpha-amylase for 24 hours, 77 +/- 6% of the starch from the flight cotyledons was degraded compared to 58 +/- 12% in ground controls. The amylose content in starch was also higher in space-grown tissues. The good correlation between the amylose content and delta X/delta rho suggests, that the magnetic susceptibility of starch grains is related to their amylose content. Since the seedlings from the BRIC-03 experiment showed elevated post-flight ethylene levels, material from another flight experiment (GENEX) which had normal levels of ethylene was examined and showed no difference to ground controls in size distribution, density, delta X/delta rho and amylose content. Therefore the role of ethylene appears to be more important for changes in starch metabolism than microgravity. c2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Materials trade study for lunar/gateway missions.

PubMed

Tripathi, R K; Wilson, J W; Cucinotta, F A; Anderson, B M; Simonsen, L C

2003-01-01

The National Aeronautics and Space Administration (NASA) administrator has identified protection from radiation hazards as one of the two biggest problems of the agency with respect to human deep space missions. The intensity and strength of cosmic radiation in deep space makes this a 'must solve' problem for space missions. The Moon and two Earth-Moon Lagrange points near Moon are being proposed as hubs for deep space missions. The focus of this study is to identify approaches to protecting astronauts and habitats from adverse effects from space radiation both for single missions and multiple missions for career astronauts to these destinations. As the great cost of added radiation shielding is a potential limiting factor in deep space missions, reduction of mass, without compromising safety, is of paramount importance. The choice of material and selection of the crew profile play major roles in design and mission operations. Material trade studies in shield design over multi-segmented missions involving multiple work and living areas in the transport and duty phase of space mission's to two Earth-Moon co-linear Lagrange points (L1) between Earth and the Moon and (L2) on back side of the moon as seen from Earth, and to the Moon have been studied. It is found that, for single missions, current state-of-the-art knowledge of material provides adequate shielding. On the other hand, the choice of shield material is absolutely critical for career astronauts and revolutionary materials need to be developed for these missions. This study also provides a guide to the effectiveness of multifunctional materials in preparation for more detailed geometry studies in progress. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Solar cosmic rays as a specific source of radiation risk during piloted space flight.

PubMed

Petrov, V M

2004-01-01

Solar cosmic rays present one of several radiation sources that are unique to space flight. Under ground conditions the exposure to individuals has a controlled form and radiation risk occurs as stochastic radiobiological effects. Existence of solar cosmic rays in space leads to a stochastic mode of radiation environment as a result of which any radiobiological consequences of exposure to solar cosmic rays during the flight will be probabilistic values. In this case, the hazard of deterministic effects should also be expressed in radiation risk values. The main deterministic effect under space conditions is radiation sickness. The best dosimetric functional for its analysis is the blood forming organs dose equivalent but not an effective dose. In addition, the repair processes in red bone marrow affect strongly on the manifestation of this pathology and they must be taken into account for radiation risk assessment. A method for taking into account the mentioned above peculiarities for the solar cosmic rays radiation risk assessment during the interplanetary flights is given in the report. It is shown that radiation risk of deterministic effects defined, as the death probability caused by radiation sickness due to acute solar cosmic rays exposure, can be comparable to risk of stochastic effects. Its value decreases strongly because of the fractional mode of exposure during the orbital movement of the spacecraft. On the contrary, during the interplanetary flight, radiation risk of deterministic effects increases significantly because of the residual component of the blood forming organs dose from previous solar proton events. The noted quality of radiation responses must be taken into account for estimating radiation hazard in space. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

Germination and elongation of flax in microgravity

NASA Technical Reports Server (NTRS)

Levine, Howard G.; Anderson, Ken; Boody, April; Cox, Dave; Kuznetsov, Oleg A.; Hasenstein, Karl H.

2003-01-01

This experiment was conducted as part of a risk mitigation payload aboard the Space Shuttle Atlantis on STS-101. The objectives were to test a newly developed water delivery system, and to determine the optimal combination of water volume and substrate for the imbibition and germination of flax (Linum usitatissimum) seeds in space. Two different combinations of germination paper were tested for their ability to absorb, distribute, and retain water in microgravity. A single layer of thick germination paper was compared with one layer of thin germination paper under a layer of thick paper. Paper strips were cut to fit snugly into seed cassettes, and seeds were glued to them with the micropyle ends pointing outward. Water was delivered in small increments that traveled through the paper via capillary action. Three water delivery volumes were tested, with the largest (480 microliters) outperforming the 400 microliters and 320 microliters volumes for percent germination (90.6%) and root growth (mean=4.1 mm) during the 34-hour spaceflight experiment. The ground control experiment yielded similar results, but with lower rates of germination (84.4%) and shorter root lengths (mean=2.8 mm). It is not clear if the roots emerged more quickly in microgravity and/or grew faster than the ground controls. The single layer of thick germination paper generally exhibited better overall growth than the two layered option. Significant seed position effects were observed in both the flight and ground control experiments. Overall, the design of the water delivery system, seed cassettes and the germination paper strip concept was validated as an effective method for promoting seed germination and root growth under microgravity conditions. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

MEP (Mars Environment Package): toward a package for studying environmental conditions at the surface of Mars from future lander/rover missions.

PubMed

Chassefière, E; Bertaux, J-L; Berthelier, J-J; Cabane, M; Ciarletti, V; Durry, G; Forget, F; Hamelin, M; Leblanc, F; Menvielle, M; Gerasimov, M; Korablev, O; Linkin, S; Managadze, G; Jambon, A; Manhès, G; Lognonné, Ph; Agrinier, P; Cartigny, P; Giardini, D; Pike, T; Kofman, W; Herique, A; Coll, P; Person, A; Costard, F; Sarda, Ph; Paillou, Ph; Chaussidon, M; Marty, B; Robert, F; Maurice, S; Blanc, M; d'Uston, C; Sabroux, J-Ch; Pineau, J-F; Rochette, P

2004-01-01

In view to prepare Mars human exploration, it is necessary to promote and lead, at the international level, a highly interdisciplinary program, involving specialists of geochemistry, geophysics, atmospheric science, space weather, and biology. The goal of this program will be to elaborate concepts of individual instruments, then of integrated instrumental packages, able to collect exhaustive data sets of environmental parameters from future landers and rovers of Mars, and to favour the conditions of their implementation. Such a program is one of the most urgent need for preparing human exploration, in order to develop mitigation strategies aimed at ensuring the safety of human explorers, and minimizing risk for surface operations. A few main areas of investigation may be listed: particle and radiation environment, chemical composition of atmosphere, meteorology, chemical composition of dust, surface and subsurface material, water in the subsurface, physical properties of the soil, search for an hypothesized microbial activity, characterization of radio-electric properties of the Martian ionosphere. Scientists at the origin of the present paper, already involved at a high degree of responsibility in several Mars missions, and actively preparing in situ instrumentation for future landed platforms (Netlander--now cancelled, MSL-09), express their readiness to participate in both ESA/AURORA and NASA programs of Mars human exploration. They think that the formation of a Mars Environment working group at ESA, in the course of the AURORA definition phase, could act positively in favour of the program, by increasing its scientific cross-section and making it still more focused on human exploration. c2004 Published by Elsevier Ltd on behalf of COSPAR.

Changes in vacuolation in the root apex cells of soybean seedlings in microgravity

NASA Technical Reports Server (NTRS)

Klymchuk, D. O.; Kordyum, E. L.; Vorobyova, T. V.; Chapman, D. K.; Brown, C. S.

2003-01-01

Changes in the vacuolation in root apex cells of soybean (Glycine max L. [Merr.]) seedlings grown in microgravity were investigated. Spaceflight and ground control seedlings were grown in the absence or presence of KMnO4 (to remove ethylene) for 6 days. After landing, in order to study of cell ultrastructure and subcellular free calcium ion distribution, seedling root apices were fixed in 2.5% (w/v) glutaraldehyde in 0.1 M cacodylate buffer and 2% (w/v) glutaraldehyde, 2.5% (w/v) formaldehyde, 2% (w/v) potassium antimonate K[Sb(OH)6] in 0.1 M K2HPO4 buffer with an osmolarity (calculated theoretically) of 0.45 and 1.26 osmol. The concentrations of ethylene in all spaceflight canisters were significantly higher than in the ground control canisters. Seedling growth was reduced in the spaceflight-exposed plants. Additionally, the spaceflight-exposed plants exhibited progressive vacuolation in the root apex cells, particularly in the columella cells, to a greater degree than the ground controls. Plasmolysis was observed in columella cells of spaceflight roots fixed in solutions with relatively high osmolarity (1.26 osmol). The appearance of plasmolysis permitted the evaluation of the water status of cells. The water potential of the spaceflight cells was higher than the surrounding fixative solution. A decrease in osmotic potential and/or an increase in turgor potential may have induced increases in cell water potential. However, the plasmolysed (i.e. non-turgid) cells implied that increases in water potential were accompanied with a decrease in osmotic potential. In such cells changes in vacuolation may have been involved to maintain turgor pressure or may have been a result of intensification of other vacuolar functions like digestion and storage. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

Growth and development in higher plants under simulated microgravity conditions on a 3-dimensional clinostat.

PubMed

Shimazu, T; Yuda, T; Miyamoto, K; Yamashita, M; Ueda, J

2001-01-01

Growth and development of etiolated pea (Pisum sativum L. cv. Alaska) and maize (Zea mays L. cv. Golden Cross Bantam) seedlings grown under simulated microgravity conditions were intensively studied using a 3-dimensional clinostat as a simulator of weightlessness. Epicotyls of etiolated pea seedlings grown on the clinostat were the most oriented toward the direction far from cotyledons. Mesocotyls of etiolated maize seedlings grew at random and coleoptiles curved slightly during clinostat rotation. Clinostat rotation promoted the emergence of the 3rd internodes in etiolated pea seedlings, while it significantly inhibited the growth of the 1st internodes. In maize seedlings, the growth of coleoptiles was little affected by clinostat rotation, but that of mesocotyls was suppressed, and therefore, the emergence of the leaf out of coleoptile was promoted. Clinostat rotation reduced the osmotic concentration in the 1st internodes of pea seedlings, although it has little effect on the 2nd and the 3rd internodes. Clinostat rotation also reduced the osmotic concentrations in both coleoptiles and mesocotyls of maize seedlings. Cell-wall extensibilities of the 1st and the 3rd internodes of pea seedlings grown on the clinostat were significantly lower and higher as compared with those on 1 g conditions, respectively. Cell-wall extensibility of mesocotyls in seedlings grown on the clinostat also decreased. Changes in cell wall properties seem to be well correlated to the growth of each organ in pea and maize seedlings. These results suggest that the growth and development of plants is controlled under gravity on earth, and that the growth responses of higher plants to microgravity conditions are regulated by both cell-wall mechanical properties and osmotic properties of stem cells. c 2001 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Advantages of using subsurface flow constructed wetlands for wastewater treatment in space applications: ground-based Mars Base prototype.

PubMed

Nelson, M; Alling, A; Dempster, W F; van Thillo, M; Allen, John

2003-01-01

Research and design of subsurface flow wetland wastewater treatment systems for a ground-based experimental prototype Mars Base facility has been carried out, using a subsurface flow approach. These systems have distinct advantages in planetary exploration scenarios: they are odorless, relatively low-labor and low-energy, assist in purification of water and recycling of atmospheric CO2, and will support some food crops. An area of 6-8 m2 may be sufficient for integration of wetland wastewater treatment with a prototype Mars Base supporting 4-5 people. Discharge water from the wetland system will be used as irrigation water for the agricultural crop area, thus ensuring complete recycling and utilization of nutrients. Since the primary requirements for wetland treatment systems are warm temperatures and lighting, such bioregenerative systems may be integrated into early Mars base habitats, since waste heat from the lights may be used for temperature maintenance in the human living environment. "Wastewater gardens (TM)" can be modified for space habitats to lower space and mass requirements. Many of its construction requirements can eventually be met with use of in-situ materials, such as gravel from the Mars surface. Because the technology requires little machinery and no chemicals, and relies more on natural ecological mechanisms (microbial and plant metabolism), maintenance requirements are minimized, and systems can be expected to have long operating lifetimes. Research needs include suitability of Martian soil and gravel for wetland systems, system sealing and liner options in a Mars Base, and wetland water quality efficiency under varying temperature and light regimes. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

The conceptual design of a hybrid life support system based on the evaluation and comparison of terrestrial testbeds.

PubMed

Czupalla, M; Horneck, G; Blome, H J

2005-01-01

This report summarizes a trade study of different options of a bioregenerative Life Support System (LSS) and a subsequent conceptual design of a hybrid LSS. The evaluation was based mainly on the terrestrial testbed projects MELISSA (ESA) and BIOS (Russia). In addition, some methods suggested by the Advanced Life Support Project (NASA) were considered. Computer models, including mass flows were established for each of the systems with the goal of closing system loops to the extent possible. In order to cope with the differences in the supported crew size and provided nutrition, all systems were scaled for supporting a crew of six for a 780 day Mars mission (180 days transport to Mars; 600 days surface period) as given in the NASA Design Reference Mission Scenario [Hoffman, S.J., Kaplan, D.L. Human exploration of Mars: the Reference Mission of the NASA Mars Exploratory Study, 1997]. All models were scaled to provide the same daily allowances, as of calories, to the crew. Equivalent System Mass (ESM) analysis was used to compare the investigated system models against each other. Following the comparison of the terrestrial systems, the system specific subsystem options for Food Supply, Solid Waste Processing, Water Management and Atmosphere Revitalization were evaluated in a separate trade study. The best subsystem technologies from the trade study were integrated into an overall design solution based on mass flow relationships. The optimized LSS is mainly a bioregenerative system, complemented by a few physico-chemical elements, with a total ESM of 18,088 kg, which is about 4 times higher than that of a pure physico-chemical LSS, as designed in an earlier study. c2005 COSPAR. Published by Elsevier Ltd. All rights reserved.

A Simple Model for the Orbital Debris Environment in GEO

NASA Astrophysics Data System (ADS)

Anilkumar, A. K.; Ananthasayanam, M. R.; Subba Rao, P. V.

The increase of space debris and its threat to commercial space activities in the Geosynchronous Earth Orbit (GEO) predictably cause concern regarding the environment over the long term. A variety of studies regarding space debris such as detection, modeling, protection and mitigation measures, is being pursued for the past couple of decades. Due to the absence of atmospheric drag to remove debris in GEO and the increasing number of utility satellites therein, the number of objects in GEO will continue to increase. The characterization of the GEO environment is critical for risk assessment and protection of future satellites and also to incorporate effective debris mitigation measures in the design and operations. The debris measurements in GEO have been limited to objects with size more than 60 cm. This paper provides an engineering model of the GEO environment by utilizing the philosophy and approach as laid out for the SIMPLE model proposed recently for LEO by the authors. The present study analyses the statistical characteristics of the GEO catalogued objects in order to arrive at a model for the GEO space debris environment. It is noted that the catalogued objects, as of now of around 800, by USSPACECOM across the years 1998 to 2004 have the same semi major axis mode (highest number density) around 35750 km above the earth. After removing the objects in the small bin around the mode, (35700, 35800) km containing around 40 percent (a value that is nearly constant across the years) of the objects, the number density of the other objects follow a single Laplace distribution with two parameters, namely location and scale. Across the years the location parameter of the above distribution does not significantly vary but the scale parameter shows a definite trend. These observations are successfully utilized in proposing a simple model for the GEO debris environment. References Ananthasayanam, M. R., Anil Kumar, A. K., and Subba Rao, P. V., ``A New Stochastic Impressionistic Low Earth (SIMPLE) Model of the Space Debris Scenario'', Conference Abstract COSPAR 02-A-01772, 2002. Ananthasayanam, M. R., Anilkumar, A. K., Subba Rao, P. V., and V. Adimurthy, ``Characterization of Eccentricity and Ballistic Coefficients of Space Debris in Altitude and Perigee Bins'', IAC-03-IAA5.p.04, Presented at the IAF Conference, Bremen, October 2003 and also to be published in the Proceedings of IAF Conference, Science and Technology Series, 2003.

Rural Roots: News, Information, and Commentary from the Rural School and Community Trust, 2002.

ERIC Educational Resources Information Center

Yaunches, Alison, Ed.; Loveland, Elaina, Ed.

2002-01-01

This document contains the six issues of "Rural Roots" published bimonthly in 2002. A newsletter of the Rural School and Community Trust, "Rural Roots" provides news, information, and commentary from the Rural Trust and highlights the wide variety of place-based education work happening in rural schools and communities across…

Washington’s forest resources: Forest Inventory and Analysis, 2002–2011

Treesearch

Justin Holgerson; Sharon Stanton; Karen Waddell; Marin Palmer; Olaf Kuegler; Glenn Christensen

2018-01-01

This report highlights key findings from data collected by the Forest Inventory and Analysis program across all forest land in the state of Washington from 2002 through 2011, updating previously published findings from data collected up to 2006. We summarize and interpret basic resource information such as forest area, composition, ownership, volume, biomass, and...

Curricular Changes in Higher Education in Mexico (2002-2012)

ERIC Educational Resources Information Center

Díaz-Barriga, Frida; Barrón, María Concepción

2014-01-01

Based on the analysis of 1241 documents published in Mexico (2002-2012) concerning curriculum studies, we find that the issue of innovation was addressed in 6 out of 10 research papers that focused on the higher education level (60.4%). It shows an increase in empirical research, quantitative and qualitative, that accounts for the process of…

Publishing for Pre-Tertiary Education in Ghana: The 2002 Textbook Policy in Retrospect

ERIC Educational Resources Information Center

Opoku-Amankwa, Kwasi; Brew-Hammond, Aba; Mahama, Anatu Kande

2015-01-01

This paper assesses the performance of the "National Textbook Development and Distribution Policy for Pre-Tertiary Education" of 2002. It examines the policy in theory and in practice by exploring the extent to which the liberalisation of the textbook trade has helped to improve on textbook procurement, production and distribution,…

News from International Clearinghouse on Children and Violence on the Screen (ICCVOS), 2002.

ERIC Educational Resources Information Center

von Feilitzen, Cecilia, Ed.

2002-01-01

This document is comprised of the two issues of the UNESCO International Clearinghouse on Children and Violence on the Screen's newsletter published in 2002, describing research findings concerning children and media violence, children's media use, and activities aimed at limiting gratuitous media violence. The first is a double issue that begins…

Empirical Reporting Practices in "Community College Journal of Research and Practice" and "Journal of Developmental Education" from 2002 to 2011: A Systematic Review

ERIC Educational Resources Information Center

Skidmore, Susan Troncoso; Zientek, Linda Reichwein; Combs, Julie P.; Fuller, Matthew B.; Hirai, Michiyo; Price, Debra P.; Moore, George W.

2014-01-01

The empirical reporting practices of developmental education and community college researchers who published in the "Community College Journal of Research and Practice" ("CCJRP") and the "Journal of Developmental Education" ("JDE") from 2002 to 2011 were investigated. Of the 1,165 articles available, 181…

37 CFR 253.10 - Cost of living adjustment.

Code of Federal Regulations, 2013 CFR

2013-07-01

... determined by the Consumer Price Index (all consumers, all items) during the period from the most recent Index published prior to December 1, 2002, to the most recent Index published prior to December 1, 2003... cost of living during the period from the most recent index published prior to the previous notice, to...

37 CFR 253.10 - Cost of living adjustment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... determined by the Consumer Price Index (all consumers, all items) during the period from the most recent Index published prior to December 1, 2002, to the most recent Index published prior to December 1, 2003... cost of living during the period from the most recent index published prior to the previous notice, to...

37 CFR 253.10 - Cost of living adjustment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... determined by the Consumer Price Index (all consumers, all items) during the period from the most recent Index published prior to December 1, 2002, to the most recent Index published prior to December 1, 2003... cost of living during the period from the most recent index published prior to the previous notice, to...

37 CFR 253.10 - Cost of living adjustment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... determined by the Consumer Price Index (all consumers, all items) during the period from the most recent Index published prior to December 1, 2002, to the most recent Index published prior to December 1, 2003... cost of living during the period from the most recent index published prior to the previous notice, to...

Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase from Shewanella oneidensis at 1.6 angstrom: Identification of Farnesyl pyrophosphate Trapped in a Hydrophobic Cavity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ni, Shuisong; Robinson, Howard; Marsing, Gregory C.

2004-11-01

1. Introduction Enzymes in the non-mevalonate pathway for isoprenoid synthesis have gained recent attention because of their potential value as targets for antibiotic drug development. 2C-methyl-D-erythritol-2,4 cyclophosphate (MECDP) synthase is the fifth enzyme in the seven enzyme non-mevalonate pathway for synthesis of isopentenyl diphosphate. Four groups have published structures of MECDP synthase at resolutions varying from 1.6Å to 2.8Å, either in the presence or absence of substrate from Escherichia coli (Richard et al., 2002; Kemp et al., 2002; Steinbacher et al., 2002) or from Thermus thermophilus (Kishida et al., 2003). Among these structures, the protein always exists as a homotrimermore » either with a crystallographic or a non-crystallographic three-fold symmetry axis and an active site formed in a cleft between adjacent monomers. While the overall shape of the proteins is highly similar among these structures, each of the four reported structures contain different combinations of metal ions in the active site including a Zn2+ ion only (Steinbacher et al., 2002), a Mn2+ ion only (Richard et al., 2002), Zn2+ and Mn2+ ions (Kemp et al., 2002) or two Mg2+ ions (Kishida et al., 2003). Furthermore, two of the structures are reported to contain a hydrophobic channel along the three-fold symmetry axis that is capped by a cluster of three arginine side chains (one from each monomer) at one end of the cavity and a cluster of three glutamic acid side chains (one from each monomer) at the other side of the cavity. In a 1.8Å resolution structure, Kemp et al. (2002) reported a sulfate ion coordinated to the arginine cap and solvent trapped in a hydrophobic cavity. In a lower 2.8Å resolution structure, Richard et al. (2002) concluded that geranyl diphosphate, GPP, was most likely trapped by the arginine cap and hydrophobic cavity (Richard et al., 2002), however, the low resolution of the data together with the presence of the crystallographic symmetry axis prohibited a definitive analysis of the identity and mode of binding of the bound molecule. Kishida et al. (2003) reported that no cavity existed in a 1.6Å structure of the SO3437 homolog from Thermus thermophilus, presumably due to tighter packing of the protein from the thermophilic organism. Steinbacher et al. (2002) make no description of a hydrophobic cavity in a lower resolution (2.5-3.2Å) of the Escherichia coli protein. Here, we report a high-resolution (1.6Å) structure of MECDP synthase from Shewanella oneidensis in the absence of substrate in the active site. We provide unambiguous data that confirms the presence of Zn2+ in one of the metal binding sites and observe what appears to be farnesyl diphosphate (FPP) bound in the hydrophobic cavity along the non-crystallographic three-fold symmetry axis of the homotrimer. The high-resolution structure clarifies the mode of binding of the pyrophosphate of FPP in the arginine cluster that caps the hydrophobic cavity.« less

10-year trend in quantity and quality of pediatric randomized controlled trials published in mainland China: 2002–2011

PubMed Central

2013-01-01

Background Quality assessment of pediatric randomized controlled trials (RCTs) in China is limited. The aim of this study was to evaluate the quantitative trends and quality indicators of RCTs published in mainland China over a recent 10-year period. Methods We individually searched all 17 available pediatric journals published in China from January 1, 2002 to December 30, 2011 to identify RCTs of drug treatment in participants under the age of 18 years. The quality was evaluated according to the Cochrane quality assessment protocol. Results Of 1287 journal issues containing 44398 articles, a total of 2.4% (1077/44398) articles were included in the analysis. The proportion of RCTs increased from 0.28% in 2002 to 0.32% in 2011. Individual sample sizes ranged from 10 to 905 participants (median 81 participants); 2.3% of the RCTs were multiple center trials; 63.9% evaluated Western medicine, 32.5% evaluated traditional Chinese medicine; 15% used an adequate method of random sequence generation; and 10.4% used a quasi-random method for randomization. Only 1% of the RCTs reported adequate allocation concealment and 0.6% reported the method of blinding. The follow-up period was from 7 days to 96 months, with a median of 7.5 months. There was incomplete outcome data reported in 8.3%, of which 4.5% (4/89) used intention-to-treat analysis. Only 0.4% of the included trials used adequate random sequence allocation, concealment and blinding. The articles published from 2007 to 2011 revealed an improvement in the randomization method compared with articles published from 2002 to 2006 (from 2.7% to 23.6%, p = 0.000). Conclusions In mainland China, the quantity of RCTs did not increase in the pediatric population, and the general quality was relatively poor. Quality improvements were suboptimal in the later 5 years. PMID:23914882

Occupational injury and illness recording and reporting requirements. Final rule.

PubMed

2001-10-12

The Occupational Safety and Health Administration (OSHA) is delaying the effective date of three provisions of the Occupational Injury and Illness Recording and Reporting Requirements rule published January 19, 2001 (66 FR 5916-6135) and is establishing interim criteria for recording cases of work-related hearing loss. The provisions being delayed are sections 1904.10 (a) and (b), which specify recording criteria for cases involving occupational hearing loss, section 1904.12, which defines "musculoskeletal disorder (MSD)" and requires employers to check the MSD column on the OSHA Log if an employee experiences a work-related musculoskeletal disorder, and section 1904.29(b)(7)(vi), which states that MSDs are not considered privacy concern cases. The effective date of these provisions is delayed from January 1, 2002 until January 1, 2003. OSHA will continue to evaluate sections 1904.10 and 1904.12 over the next year. OSHA is also adding a new paragraph(c) to section 1904.10, establishing criteria for recording cases of work-related hearing loss during calendar year 2002. Section 1904.10(c) codifies the enforcement policy in effect since 1991, under which employers must record work related shifts in hearing of an average of 25 dB or more at 2000, 3000 and 4000 hertz in either ear.

Introduction to an Updated Analysis of Planetary Protection: "Special Regions" on Mars

NASA Astrophysics Data System (ADS)

Beaty, D. W.; Rummel, J. D.; Viola, D.

2014-03-01

Since the beginning of human activity in space science and exploration, there has been an appreciation of the negative consequences of transferring life from one planet to another. Given the unknown consequences of contact between two life forms and the fundamental value of studying a new form life, thoughtfulness and caution are warranted. The "special regions" concept is a component of the International Council for Science's Committee on Space Research (COSPAR) Planetary Protection Policy, as it applies to Mars. These are regions "within which terrestrial organisms are likely to replicate" as well as "any region which is interpreted to have a high potential for the existence of extant martian life." Robotic missions planning to have direct contact with such special regions are given planetary protection categorization (IVc), with stringent cleanliness constraints on the portions of the mission contacting such regions. The current, quantitative definition of "special regions based on temperature and water activity limits was adopted by COSPAR in 2008 after a two-year process that included meetings of the Mars Exploration Planning and Analysis Group's (MEPAG) Special Regions Science Analysis Group (SR-SAG) and COSPAR's Panel on Planetary Protection. In this study, the MEPAG SR-SAG2 will review and update the technical information that underlie NASA's and COSPAR's definition of special regions on Mars, enabling interpretations of when and where they could occur in light of new discoveries since 2007. This will include updates of current understanding in (1) the known physical limits to life on Earth, including low temperature and low water activity, the biological capture/use of vapor-phase water, and survival over long time scales with short periods of growth; (2) observational data sets and new models from Mars that could be relevant to our understanding of the natural variations on Mars of water activity and temperature, including recurring slope lineae (RSL), gullies, the distribution of surface and subsurface ice, brine stability, and atmosphere-regolith interactions; and (3) mineral and amorphous material water content and its potential biological availability, including mineral deliquescence. This information will be used to reconsider the parameters used to define the term "special region," including the temperature and water activity thresholds, timescales for the existence of a special region (episodic or continuous), and the spatial scale used to apply "special" or "non-special" designations. Additionally, both text and map forms will be prepared, describing Mars environments that are judged to be "special" or for which there is a significant (but still unknown) probability that the threshold conditions for a special region would be exceeded within the assumed 500-year limit. A preliminary analysis of the kinds and amounts of water-related resources on Mars of potential interest to the eventual human exploration of Mars will also be performed, and the planetary protection implications of attempting to access/exploit them will be evaluated. Members of the community who have information on any of these topics are encouraged to contact one of the authors of this abstract.

78 FR 57175 - Notice of Lodging of Consent Decree Pursuant to the Clean Air Act

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-17

...'') for violations of Section 504 of the Clean Water Act, 33 U.S.C. 1364(a), and Section 44- 55-90(C)(2002 & Supp. 2011) of the South Carolina Safe Drinking Water Act (``SC SDWA''), S.C. Code Ann. Sec. 44-55-90 (C) (2002 & Supp. 2011), Section 309(b) and (d) of the Clean Water Act, 33 U.S.C. 1319(b) and (d...

Book Trade Research and Statistics. Prices of U.S. and Foreign Published Materials; Book Title Output and Average Prices: 2001 Final and 2002 Preliminary Figures; Book Sales Statistics, 2002: AAP Preliminary Estimates; U.S. Book Exports and Imports:2002; Number of Book Outlets in the United States and Canada; Review Media Statistics.

ERIC Educational Resources Information Center

Sullivan, Sharon G.; Grabois, Andrew; Greco, Albert N.

2003-01-01

Includes six reports related to book trade statistics, including prices of U.S. and foreign materials; book title output and average prices; book sales statistics; book exports and imports; book outlets in the U.S. and Canada; and numbers of books and other media reviewed by major reviewing publications. (LRW)

Estimates of the population prevalence of injection drug users among hispanic residents of large US metropolitan areas.

PubMed

Pouget, Enrique R; Friedman, Samuel R; Cleland, Charles M; Tempalski, Barbara; Cooper, Hannah L F

2012-06-01

Little information exists on the population prevalence or geographic distribution of injection drug users (IDUs) who are Hispanic in the USA. Here, we present yearly estimates of IDU population prevalence among Hispanic residents of the 96 most populated US metropolitan statistical areas (MSAs) for 1992-2002. First, yearly estimates of the proportion of IDUs who were Hispanic in each MSA were created by combining data on (1) IDUs receiving drug treatment services in Substance Abuse and Mental Health Services Administration (SAMHSA)'s Treatment Entry Data System, (2) IDUs being tested in the Centers for Disease Control and Prevention (CDC) HIV-Counseling and Testing System, and (3) incident AIDS diagnoses among IDUs, supplemented by (4) data on IDUs who were living with AIDS. Then, the resulting proportions were multiplied by published yearly estimates of the number of IDUs of all racial/ethnic groups in each MSA to produce Hispanic IDU population estimates. These were divided by Hispanic population data to produce population prevalence rates. Time trends were tested using mixed-effects regression models. Hispanic IDU prevalence declined significantly on average (1992 mean = 192, median = 133; 2002 mean = 144, median = 93; units are per 10,000 Hispanics aged 15-64). The highest prevalence rates across time tended to be in smaller northeastern MSAs. Comparing the last three study years to the first three, prevalence decreased in 82% of MSAs and increased in 18%. Comparisons with data on drug-related mortality and hepatitis C mortality supported the validity of the estimates. Generally, estimates of Hispanic IDU population prevalence were higher than published estimates for non-Hispanic White residents and lower than published estimates for non-Hispanic Black residents. Further analysis indicated that the proportion of IDUs that was Hispanic decreased in 52% and increased in 48% of MSAs between 2002 and 2007. The estimates resulting from this study can be used to investigate MSA-level social and economic factors that may have contributed to variations across MSAs and to help guide prevention program planning for Hispanic IDUs within MSAs. Future research should attempt to determine to what extent these trends are applicable to Hispanic national origin subgroups.

[Analysis of the citation of the articles published in National Journal of Andrology by SCI periodicals from 2002 to 2008].

PubMed

Huang, Hai

2009-03-01

Science Citation Index (SCI) is one of the world's most important and influential information retrieval systems. Today Web of Science covers over 9000 international and regional journals and book series in every field of natural sciences, social sciences, and arts and humanities. More and more Chinese periodicals have been cited by SCI. This paper briefly introduces the SCI database and its selection process and analyzes the citation of the articles published in National Journal of Andrology (NJA) by SCI journals from 2002 to 2008, aiming to provide some information for the internationalization of NJA.

Science Directorate Publications and Presentations, January 1 - December 31, 2002

NASA Technical Reports Server (NTRS)

Summers, F. G. (Compiler)

2003-01-01

This Technical Memorandum lists the significant publications and presentations of the Science Directorate during the period January 1-December 31, 2002. Entries in the main part of the document are categorized according to NASA Reports (arranged by report number), Open Literature, and Presentations (arranged alphabetically by title). Most of the articles listed under Open Literature have appeared in refereed professional journals, books, monographs, or conference proceedings. Although many published abstracts are eventually expanded into full papers for publication in scientific and technical journals, they are often sufficiently comprehensive to include the significant results of the research reported. Therefore, published abstracts are listed separately in a subsection under Open Literature.

Update on inflation of journal prices: Brandon/Hill list journals and the scientific, technical, and medical publishing market.

PubMed

Schlimgen, Joan B; Kronenfeld, Michael R

2004-07-01

The original study of journal prices, using the "Brandon/ Hill Selected List of Books and Journals for the Small Medical Library," was first published in 1980 and periodically updated. This research continues to measure price increases for these titles for the periods 1996 to 1999 and 1999 to 2002. The 111 journal titles that have appeared in each published list from 1967 to 2001 were included in the study. Institutional subscription price data were gathered for each journal for the years 1996, 1999, and 2002 and were compared to the Consumer Price Index (CPI) for the same years. The average journal price continues to rise significantly and is independent of the CPI. The study found that prices have jumped 51.9% from 1996 to 1999 and 32% from 1999 to 2002, which is consistent with nearly every recent journal price study. The unprecedented rise in journal prices negatively affects the purchasing power of medical libraries. This paper examines the economic and technological pressures on the science, technology, and medical journals market that contribute to high prices and identifies a number of initiatives in the biological and health sciences that utilize alternative models for disseminating scientific research.

Life sciences and space research 25 (1). Gravitational biology; Interdisciplinary Scientific Commission F of the COSPAR Plenary Meeting, 29th, Washington, DC, Aug. 28-Sep. 5, 1992

NASA Technical Reports Server (NTRS)

Cogoli, A. (Editor); Cogoli-Greuter, M. (Editor); Gruener, R. (Editor); Sievers, A. (Editor); Ubbels, G. A. (Editor); Halstead, T. W. (Editor); Ross, M. D. (Editor); Roux, S. J. (Editor); Oser, H. (Editor); Lujan, B. F. (Editor)

1994-01-01

The conference includes papers describing theories and models of cell biology in microgravity and weightlessness; experimental research on cellular responses to altered gravity in plants and animals, natural and simulated; graviresponses in plants; gravitational effects in developmental biology; mechanisms of gravisensing; effects on animals and humans; and educational programs in Space Life Sciences.

Space life sciences: search for signatures of life, and space flight environmental effects on the nervous system.

PubMed

2004-01-01

This volume contains selected papers of the Joint COSPAR-IAC event "Search for signatures of life in the solar system, terrestrial analogues and simulation experiments" held during the World Space Congress 2002 in Houston, Texas, USA. The first section of the volume reports on the rich variety of terrestrial microbial communities adapted to extreme environments, such as microbial life at very low temperatures in permafrost and ice layers, at high salt concentrations, as inhabitants of rocks and the microbial recolonization of impact-shocked rocks. These communities are suggested to serve as analogues for extraterrestrial habitats, which are also described in this section. The second section deals with the detection of biomarkers and signatures from extinct life on Earth, which might provide clues for detection of potential extraterrestrial biomarkers. This section is followed by reports of experiments in space and in the laboratory simulating space conditions, such as the prebiotic organic chemistry, the chemistry of dust particles to be detected during the Cassini mission to Saturn, as well as the photochemistry of biological systems exposed to space or planetary surface conditions. The second part of the issue contains papers from the session "The nervous system: space flight environmental factors effects--present results and new perspectives." The presentations in this session explored various aspects of the effects of exposure to protons and heavy particles on central nervous system function and on behavior. The second series of papers examines the effects of exposure to heavy particles and protons on neurochemistry and on behavior.

The Ability of Beginning University Chemistry Students to Use ICT (Information and Communication Technology) in Their Learning in 2002

ERIC Educational Resources Information Center

Lim, Kieran F.

2003-01-01

There is an assumption that high-school students are becoming more computer literate, but published studies of specific skill level are lacking. An anonymous multiple-choice survey self-assessed the ICT (information and communication technology) skills of first-year chemistry students at the beginning of 2002. The general level of ICT skill…

Work and Family Research in IO/OB: Content Analysis and Review of the Literature (1980-2002)

ERIC Educational Resources Information Center

Eby, Lillian T.; Casper, Wendy J.; Lockwood, Angie; Bordeaux, Chris; Brinley, Andi

2005-01-01

This monograph reviews 190 work-family studies published in IO/OB journals from 1980 to 2002. The results of a content analysis are presented which catalog these articles with respect to the study focus, nature and direction of the proposed effects, and predictor, criterion, and mediator variables examined. Then a narrative review of the articles…

Social Change and Dissent in Iran

DTIC Science & Technology

2003-05-01

on Opioid Agonist Maintenance Treatment (2002) Tehran, Iran, 25-27 June. UNODCCP (2002) Global illicit drug trends (yearly report). New York...Tabrizi, Assistant Professor of Sociology, Georgia State University: Iran: A Solution Rather Than A Problem : The Politics Of Reform Mr. Afshin Molavi...published numerous articles on the topics of Islam and science, post-modernity and Islamic movements, and globalization and human rights. Dr. Kaveh

75 FR 23565 - Food Stamp Program: Eligibility and Certification Provisions of the Farm Security and Rural...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-04

...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0...: Eligibility and Certification Provisions of the Farm Security and Rural Investment Act of 2002; Approval of...: Eligibility and Certification Provisions of the Farm Security and Rural Investment Act of 2002, was published...

Citation Structure: An Analysis of the Literature Cited in the "Journal of Leadership Education" from 2002 to 2006

ERIC Educational Resources Information Center

Edgar, Leslie D.; Cox, Casandra

2010-01-01

The "Journal of Leadership Education (JOLE)" has been a primary outlet of leadership education publishing and research dissemination since 2002. The purpose of this study was to assess the first five years of literature cited in "JOLE". The study used a quantitative content analysis design. Analyzed in the study were 45…

Revisiting Manzanar: A History of Japanese American Internment Camps as Presented in Selected Federal Government Documents, 1941-2002

ERIC Educational Resources Information Center

Parks, Kimberley Roberts

2004-01-01

Starting with a U.S. presidential proclamation regarding Japanese enemy aliens on December 7, 1941, through legislative and educational information in 2002, the federal government of the United States has published, in varied media, numerous documents concerning its 1942-1945 internment of persons of Japanese ancestry living on the West Coast.…

Automation and Robotics for Human Mars Exploration (AROMA)

NASA Technical Reports Server (NTRS)

Hofmann, Peter; von Richter, Andreas

2003-01-01

Automation and Robotics (A&R) systems are a key technology for Mars exploration. All over the world initiatives in this field aim at developing new A&R systems and technologies for planetary surface exploration. From December 2000 to February 2002 Kayser-Threde GmbH, Munich, Germany lead a study called AROMA (Automation and Robotics for Human Mars Exploration) under ESA contract in order to define a reference architecture of A&R elements in support of a human Mars exploration program. One of the goals of this effort is to initiate new developments and to maintain the competitiveness of European industry within this field. c2003 Published by Elsevier Science Ltd.

Automation and Robotics for Human Mars Exploration (AROMA).

PubMed

Hofmann, Peter; von Richter, Andreas

2003-01-01

Automation and Robotics (A&R) systems are a key technology for Mars exploration. All over the world initiatives in this field aim at developing new A&R systems and technologies for planetary surface exploration. From December 2000 to February 2002 Kayser-Threde GmbH, Munich, Germany lead a study called AROMA (Automation and Robotics for Human Mars Exploration) under ESA contract in order to define a reference architecture of A&R elements in support of a human Mars exploration program. One of the goals of this effort is to initiate new developments and to maintain the competitiveness of European industry within this field. c2003 Published by Elsevier Science Ltd.

Policy Failures in the Graveyard of Empires: How Policymakers Let the Soldiers Down in the British, the Soviet, and the American Wars in Afghanistan

DTIC Science & Technology

2011-05-19

Publishers Ltd, 2002), 248. 228 Ibid. 229 Hugh Chisholm, Encyclopedia Britannica (Eleventh Edition, Published 1910-11), Library of Fogg Museum of Art...Washington DC: National Defense University Press, 1986. Chisholm, Hugh. Encyclopedia Britannica (Eleventh Edition, Published 1910-11), Library of Fogg

Creatinine elevation associated with nitromethane exposure: a marker of potential methanol toxicity.

PubMed

Cook, Matthew D; Clark, Richard F

2007-10-01

Nitromethane, methanol, and oil are the common components of radio-controlled (R/C) vehicle fuels. Nitromethane can cause a false elevation of serum creatinine concentration as measured by the widely used Jaffe colorimetric method. We gathered data from our poison control system and from previously published case reports to see if a correlation exists between serum methanol concentrations and spuriously elevated serum creatinine concentrations after human exposures to R/C fuel. The California Poison Control System (CPCS) computerized database was queried for all cases of human exposure to R/C vehicle fuel reported between December 1, 2002 and December 1, 2004. Serum creatinine and methanol concentrations were recorded when available, as was the method used to determine serum creatinine. A MEDLINE search was used to obtain previously published cases of human nitromethane exposure associated with falsely elevated creatinine concentrations. During the 2-year period, serum creatinine concentrations were recorded in 7 of 26 R/C fuel exposures (all ingestions), and 6 of these were abnormal (range of 1.9-11.5 mg/dL). In this series, the higher the serum creatinine concentration measured by Jaffe method, the higher the serum methanol concentration. The MEDLINE search yielded data from six previously published case reports on this topic. The data from these case reports seem to follow the trend seen in our case series. These data suggest that a spuriously elevated serum creatinine (by Jaffe method) may have value as an early surrogate marker of methanol poisoning in those who ingest R/C fuel. Also, the degree to which the serum creatinine is elevated may indicate the severity of methanol poisoning.

A new dynamical atmospheric ionizing radiation (AIR) model for epidemiological studies

NASA Technical Reports Server (NTRS)

De Angelis, G.; Clem, J. M.; Goldhagen, P. E.; Wilson, J. W.

2003-01-01

A new Atmospheric Ionizing Radiation (AIR) model is currently being developed for use in radiation dose evaluation in epidemiological studies targeted to atmospheric flight personnel such as civilian airlines crewmembers. The model will allow computing values for biologically relevant parameters, e.g. dose equivalent and effective dose, for individual flights from 1945. Each flight is described by its actual three dimensional flight profile, i.e. geographic coordinates and altitudes varying with time. Solar modulated primary particles are filtered with a new analytical fully angular dependent geomagnetic cut off rigidity model, as a function of latitude, longitude, arrival direction, altitude and time. The particle transport results have been obtained with a technique based on the three-dimensional Monte Carlo transport code FLUKA, with a special procedure to deal with HZE particles. Particle fluxes are transformed into dose-related quantities and then integrated all along the flight path to obtain the overall flight dose. Preliminary validations of the particle transport technique using data from the AIR Project ER-2 flight campaign of measurements are encouraging. Future efforts will deal with modeling of the effects of the aircraft structure as well as inclusion of solar particle events. Published by Elsevier Ltd on behalf of COSPAR.

Review and analysis of over 40 years of space plant growth systems.

PubMed

Zabel, P; Bamsey, M; Schubert, D; Tajmar, M

2016-08-01

The cultivation of higher plants occupies an essential role within bio-regenerative life support systems. It contributes to all major functional aspects by closing the different loops in a habitat like food production, CO2 reduction, O2 production, waste recycling and water management. Fresh crops are also expected to have a positive impact on crew psychological health. Plant material was first launched into orbit on unmanned vehicles as early as the 1960s. Since then, more than a dozen different plant cultivation experiments have been flown on crewed vehicles beginning with the launch of Oasis 1, in 1971. Continuous subsystem improvements and increasing knowledge of plant response to the spaceflight environment has led to the design of Veggie and the Advanced Plant Habitat, the latest in the series of plant growth systems. The paper reviews the different designs and technological solutions implemented in higher plant flight experiments. Using these analyses a comprehensive comparison is compiled to illustrate the development trends of controlled environment agriculture technologies in bio-regenerative life support systems, enabling future human long-duration missions into the solar system. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Concepts and challenges in cancer risk prediction for the space radiation environment.

PubMed

Barcellos-Hoff, Mary Helen; Blakely, Eleanor A; Burma, Sandeep; Fornace, Albert J; Gerson, Stanton; Hlatky, Lynn; Kirsch, David G; Luderer, Ulrike; Shay, Jerry; Wang, Ya; Weil, Michael M

2015-07-01

Cancer is an important long-term risk for astronauts exposed to protons and high-energy charged particles during travel and residence on asteroids, the moon, and other planets. NASA's Biomedical Critical Path Roadmap defines the carcinogenic risks of radiation exposure as one of four type I risks. A type I risk represents a demonstrated, serious problem with no countermeasure concepts, and may be a potential "show-stopper" for long duration spaceflight. Estimating the carcinogenic risks for humans who will be exposed to heavy ions during deep space exploration has very large uncertainties at present. There are no human data that address risk from extended exposure to complex radiation fields. The overarching goal in this area to improve risk modeling is to provide biological insight and mechanistic analysis of radiation quality effects on carcinogenesis. Understanding mechanisms will provide routes to modeling and predicting risk and designing countermeasures. This white paper reviews broad issues related to experimental models and concepts in space radiation carcinogenesis as well as the current state of the field to place into context recent findings and concepts derived from the NASA Space Radiation Program. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Biodegradation pathway of an anionic surfactant (Igepon TC-42) during recycling waste water through plant hydroponics for advanced life support during long-duration space missions.

PubMed

Levine, L H; Kagie, H R; Garland, J L

2003-01-01

The degradation of an anionic surfactant (Igepon TC-42) was investigated as part of an integrated study of direct recycling of human hygiene water through hydroponic plant growth systems. Several chemical approaches were developed to characterize the degradation of Igepon and to measure the accumulation of intermediates such as fatty acids and methyl taurine. Igepon was rapidly degraded as indicated by the reduction of methylene blue active substances (MBAS) and component fatty acids. The Igepon degradation rate continued to increase over a period of several weeks following repeated daily exposure to 18 micrograms/l Igepon. The accumulation of free fatty acids and methyl taurine was also observed during decomposition of Igepon. The concentration of methyl taurine was below detection limit (0.2 nmol/ml) during the slow phase of Igepon degradation, and increased to 1-2 nmol/ml during the phase of rapid degradation. These findings support a degradation pathway involving initial hydrolysis of amide to release fatty acids and methyl taurine, and subsequent degradation of these intermediates. Published by Elsevier Science Ltd on behalf of COSPAR.

Vertical Crustal Motion Derived from Satellite Altimetry and Tide Gauges, and Comparisons with DORIS Measurements

NASA Technical Reports Server (NTRS)

Ray, R. D.; Beckley, B. D.; Lemoine, F. G.

2010-01-01

A somewhat unorthodox method for determining vertical crustal motion at a tide-gauge location is to difference the sea level time series with an equivalent time series determined from satellite altimetry, To the extent that both instruments measure an identical ocean signal, the difference will be dominated by vertical land motion at the gauge. We revisit this technique by analyzing sea level signals at 28 tide gauges that are colocated with DORIS geodetic stations. Comparisons of altimeter-gauge vertical rates with DORIS rates yield a median difference of 1.8 mm/yr and a weighted root-mean-square difference of2.7 mm/yr. The latter suggests that our uncertainty estimates, which are primarily based on an assumed AR(l) noise process in all time series, underestimates the true errors. Several sources of additional error are discussed, including possible scale errors in the terrestrial reference frame to which altimeter-gauge rates are mostly insensitive, One of our stations, Male, Maldives, which has been the subject of some uninformed arguments about sea-level rise, is found to have almost no vertical motion, and thus is vulnerable to rising sea levels. Published by Elsevier Ltd. on behalf of COSPAR.

Biodegradation pathway of an anionic surfactant (Igepon TC-42) during recycling waste water through plant hydroponics for advanced life support during long-duration space missions

NASA Technical Reports Server (NTRS)

Levine, L. H.; Kagie, H. R.; Garland, J. L.

2003-01-01

The degradation of an anionic surfactant (Igepon TC-42) was investigated as part of an integrated study of direct recycling of human hygiene water through hydroponic plant growth systems. Several chemical approaches were developed to characterize the degradation of Igepon and to measure the accumulation of intermediates such as fatty acids and methyl taurine. Igepon was rapidly degraded as indicated by the reduction of methylene blue active substances (MBAS) and component fatty acids. The Igepon degradation rate continued to increase over a period of several weeks following repeated daily exposure to 18 micrograms/l Igepon. The accumulation of free fatty acids and methyl taurine was also observed during decomposition of Igepon. The concentration of methyl taurine was below detection limit (0.2 nmol/ml) during the slow phase of Igepon degradation, and increased to 1-2 nmol/ml during the phase of rapid degradation. These findings support a degradation pathway involving initial hydrolysis of amide to release fatty acids and methyl taurine, and subsequent degradation of these intermediates. Published by Elsevier Science Ltd on behalf of COSPAR.

Studies toward birth and early mammalian development in space

NASA Astrophysics Data System (ADS)

Ronca, April E.

2003-10-01

Sustaining life beyond Earth on either space stations or other planets will require a clear understanding of how the space environment affects key phases of mammalian reproduction and development. Pregnancy, parturition (birth) and the early development of offspring are complex processes essential for successful reproduction and the proliferation of mammalian species. While no mammal has yet undergone birth within the space environment, studies spanning the gravity continuum from 0- to 2-g are revealing startling insights into how reproduction and development may proceed under gravitational conditions deviating from those typically experienced on Earth. In this report, I review studies of pregnant Norway rats and their offspring flown in microgravity (μg) onboard the NASA Space Shuttle throughout the period corresponding to mid- to late gestation, and analogous studies of pregnant rats exposed to hypergravity ( ht) onboard the NASA Ames Research Center 24-ft centrifuge. Studies of postnatal rats flown in space or exposed to centrifugation are reviewed. Although many important questions remain unanswered, the available data suggest that numerous aspects of pregnancy, birth and early mammalian development can proceed under altered gravity conditions. Published by Elsevier Ltd on behalf of COSPAR.

Lessons learned using different mouse models during space radiation-induced lung tumorigenesis experiments.

PubMed

Wang, Jian; Zhang, Xiangming; Wang, Ping; Wang, Xiang; Farris, Alton B; Wang, Ya

2016-06-01

Unlike terrestrial ionizing radiation, space radiation, especially galactic cosmic rays (GCR), contains high energy charged (HZE) particles with high linear energy transfer (LET). Due to a lack of epidemiologic data for high-LET radiation exposure, it is highly uncertain how high the carcinogenesis risk is for astronauts following exposure to space radiation during space missions. Therefore, using mouse models is necessary to evaluate the risk of space radiation-induced tumorigenesis; however, which mouse model is better for these studies remains uncertain. Since lung tumorigenesis is the leading cause of cancer death among both men and women, and low-LET radiation exposure increases human lung carcinogenesis, evaluating space radiation-induced lung tumorigenesis is critical to enable safe Mars missions. Here, by comparing lung tumorigenesis obtained from different mouse strains, as well as miR-21 in lung tissue/tumors and serum, we believe that wild type mice with a low spontaneous tumorigenesis background are ideal for evaluating the risk of space radiation-induced lung tumorigenesis, and circulating miR-21 from such mice model might be used as a biomarker for predicting the risk. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Space radiation protection: Destination Mars.

PubMed

Durante, Marco

2014-04-01

National space agencies are planning a human mission to Mars in the XXI century. Space radiation is generally acknowledged as a potential showstopper for this mission for two reasons: a) high uncertainty on the risk of radiation-induced morbidity, and b) lack of simple countermeasures to reduce the exposure. The need for radiation exposure mitigation tools in a mission to Mars is supported by the recent measurements of the radiation field on the Mars Science Laboratory. Shielding is the simplest physical countermeasure, but the current materials provide poor reduction of the dose deposited by high-energy cosmic rays. Accelerator-based tests of new materials can be used to assess additional protection in the spacecraft. Active shielding is very promising, but as yet not applicable in practical cases. Several studies are developing technologies based on superconducting magnetic fields in space. Reducing the transit time to Mars is arguably the best solution but novel nuclear thermal-electric propulsion systems also seem to be far from practical realization. It is likely that the first mission to Mars will employ a combination of these options to reduce radiation exposure. Copyright © 2014 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Microgels for long-term storage of vitamins for extended spaceflight.

PubMed

Schroeder, R

2018-02-01

Biocompatible materials that can encapsulate large amounts of nutrients while protecting them from degrading environmental influences are highly desired for extended manned spaceflight. In this study, alkaline-degradable microgels based on poly(N-vinylcaprolactam) (PVCL) were prepared and analysed with their regard to stabilise retinol which acts as a model vitamin (vitamin A 1 ). It was investigated whether the secondary crosslinking of the particles with a polyphenol can prevent the isomerisation of biologically active all-trans retinol to biologically inactive cis-trans retinol. Both loading with retinol and secondary crosslinking of the particles was performed at room temperature to prevent an early degradation of the vitamin. This study showed that PVCL microgels drastically improve the water solubility of hydrophobic retinol. Additionally, it is demonstrated that the highly crosslinked microgel particles in aqueous solution can be utilised to greatly retard the light- and temperature-induced isomerisation process of retinol by a factor of almost 100 compared to pure retinol stored in ethanol. The use of microgels offers various advantages over other drug delivery systems as they exhibit enhanced biocompatibility and superior aqueous solubility. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

77 FR 27849 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

...-5748; FMCSA-2001-11426; FMCSA-2002-11714; FMCSA- 2009-0011; FMCSA-2010-0050] Qualification of Drivers... Federal Docket Management System (FDMS) numbers: FMCSA-1999-5748; FMCSA-2001-11426; FMCSA-2002-11714...) Lawrence C. Moody (NJ) Stanley W. Nunn (TN) Bobby C. Spencer (TN) Kevin R. Stoner (PA) The exemptions are...

Enhanced production of lovastatin by Omphalotus olearius (DC.) Singer in solid state fermentation.

PubMed

Atlı, Burcu; Yamaç, Mustafa; Yıldız, Zeki; Isikhuemnen, Omoanghe S

2015-01-01

Although lovastatin production has been reported for different microorganism species, there is limited information about lovastatin production by basidiomycetes. The optimization of culture parameters that enhances lovastatin production by Omphalotus olearius OBCC 2002 was investigated, using statistically based experimental designs under solid state fermentation. The Plackett Burman design was used in the first step to test the relative importance of the variables affecting production of lovastatin. Amount and particle size of barley were identified as efficient variables. In the latter step, the interactive effects of selected efficient variables were studied with a full factorial design. A maximum lovastatin yield of 139.47mg/g substrate was achieved by the fermentation of 5g of barley, 1-2mm particle diam., at 28°C. This study showed that O. olearius OBCC 2002 has a high capacity for lovastatin production which could be enhanced by using solid state fermentation with novel and cost-effective substrates, such as barley. Copyright © 2013 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

El Programa de Fortalecimiento de Capacidades de COSPAR

NASA Astrophysics Data System (ADS)

Gabriel, C.

2016-08-01

The provision of scientific data archives and analysis tools by diverse institutions in the world represents a unique opportunity for the development of scientific activities. An example of this is the European Space Agency's space observatory XMM-Newton with its Science Operations Centre at the European Space Astronomy Centre near Madrid, Spain. It provides through its science archive and web pages, not only the raw and processed data from the mission, but also analysis tools, and full documentation greatly helping their dissemination and use. These data and tools, freely accesible to anyone in the world, are the practical elements around which COSPAR (COmmittee on SPAce Research) Capacity Building Workshops have been conceived and developed, and held for a decade and a half in developing countries. The Programme started with X-ray workshops, but in-between it has been broadened to the most diverse space science areas. The workshops help to develop science at the highest level in those countries, in a long and substainable way, with a minimal investment (computer plus a moderate Internet connection). In this paper we discuss the basis, concepts, and achievements of the Capacity Building Programme. Two instances of the Programme have already taken place in Argentina, one of them devoted to X-ray astronomy and another to Infrared Astronomy. Several others have been organised for the Latin American region (Brazil, Uruguay and Mexico) with a large participation of young investigators from Argentina.

Planetary Protection Constraints For Planetary Exploration and Exobiology

NASA Astrophysics Data System (ADS)

Debus, A.; Bonneville, R.; Viso, M.

According to the article IX of the OUTER SPACE TREATY (London / Washington January 27., 1967) and in the frame of extraterrestrial missions, it is required to preserve planets and Earth from contamination. For ethical, safety and scientific reasons, the space agencies have to comply with the Outer Space Treaty and to take into account the related planetary protection Cospar recommendations. Planetary protection takes also into account the protection of exobiological science, because the results of life detection experimentations could have impacts on planetary protection regulations. The validation of their results depends strongly of how the samples have been collected, stored and analyzed, and particularly of their biological and organic cleanliness. Any risk of contamination by organic materials, chemical coumpounds and by terrestrial microorganisms must be avoided. A large number of missions is presently scheduled, particularly on Mars, in order to search for life or traces of past life. In the frame of such missions, CNES is building a planetary protection organization in order handle and to take in charge all tasks linked to science and engineering concerned by planetary protection. Taking into account CNES past experience in planetary protection related to the Mars 96 mission, its planned participation in exobiological missions with NASA as well as its works and involvement in Cospar activities, this paper will present the main requirements in order to avoid celestial bodies biological contamination, focussing on Mars and including Earth, and to protect exobiological science.

Revision to Planetary Protection Policy for Mars Missions

NASA Technical Reports Server (NTRS)

DeVincenzi, D. L.; Stabekis, P.; Barengoltz, J.; Morrison, David (Technical Monitor)

1994-01-01

Under existing COSPAR policy adopted in 1984, missions to Mars (landers, probes, and some orbiters) are designated as Category IV missions. As such, the procedures for implementing planetary protection requirements could include trajectory biasing, cleanrooms, bioload reduction, sterilization of hardware, and bioshields, i. e. requirements could be similar to Viking. However, in 1992, a U. S. National Academy of Sciences study recommended that controls on forward contamination of Mars be tied to specific mission objectives. The report recommended that Mars landers with life detection instruments be subject to at least Viking-level sterilization procedures for bioload reduction, while spacecraft (including orbiters) without life detection instruments be subject to at least Viking-level pre sterilization procedures for bioload reduction but need not be sterilized. In light of this, it is proposed that the current policy's Category IV missions and their planetary protection requirements be divided into two subcategories as follows: Category IV A, for missions comprising landers and probes without life detection experiments and some orbiters, which will meet a specified bioburden limit for exposed surfaces; Category IV B, for landers and probes with life detection experiments, which will require complete system sterilization. For Category IV A missions, bioburden specifications will be proposed and implementing procedures discussed. A resolution will be proposed to modify the existing COSPAR policy to reflect these changes. Similar specifications, procedures, and resolution for Category IV B missions will be the subject of a later study.

Living systems in hypomagnetic conditions of Space

NASA Astrophysics Data System (ADS)

Trukhanov, Kirill; Gurieva, Tamara; Dadasheva, Olga; Spassky, Andrey; Lebedev, Viktor; Kruglov, Oleg

When working at a long-term lunar base, at stations in the near-moon space and during interplanetary missions cosmonauts will be continuously exposed to an entirely new environmental factor - hypomagnetic conditions (HMC). Interplanetary magnetic field and the field on the Lunar surface is three-five orders of magnitude below the usual geomagnetic field (GMF). It is well known that exposure to even a slightly decreased GMF adversely affect human and other living systems. Nervous, endocrine, cardiovascular systems and blood are considered to be the most sensitive to reduced GMF. There are some data in literature about the significant vulnerability of developing organism to the HMC. In this paper we present the results of further studies on the impact of the HMC on the embryogenesis of the Japanese quail (Coturnix coturnix japonica), including the works performed as the development of studies reported at the conferences COSPAR 37 and COSPAR 39. Duration of quail embryos exposure to different values of attenuation HMC (till thousandfold and more) came up to 18 days. It is shown that the prolonged exposure to the HMC heightens the adverse effects on embryogenesis. The background of alternating electromagnetic fields of the systems and equipment will exist at the habitable base or on the board of the spacecraft. The results of studies on the combined effects of HMC and weak alternating magnetic fields are also presented.

C (G)-Band & X (I) - Band Noncoherent Radar Transponder Performance Specification Standard

DTIC Science & Technology

2002-04-01

TRAINING RANGE NEVADA TEST SITE STANDARD 262-02 ELECTRONIC TRAJECTORY MEASUREMENTS GROUP C (G) – BAND & X (I) – BAND NONCOHERENT RADAR...Date 00 Apr 2002 Report Type N/A Dates Covered (from... to) - Title and Subtitle C (G)-Band & X (I) - Band Noncoherent Radar Transponder...Number of Pages 157 i STANDARD 262-02 C (G) – BAND & X (I) – BAND NONCOHERENT RADAR TRANSPONDER PERFORMANCE SPECIFICATION STANDARD APRIL 2002 Prepared by

Department Of Defense September 2002 Adult Poll Overview Report

DTIC Science & Technology

2003-04-01

American Poll C-17 20. Men of Honor 21. Pearl Harbor 22. Platoon 23. Rambo Series 24. Rules Of Engagement 25. Saving Private Ryan 26. Sum of...23. Rambo Series 24. Rules Of Engagement 25. Saving Private Ryan September 2002 Department of Defense Adult American Poll C-18 26. Sum of

11 CFR 9405.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... information for a use or purpose that furthers his/her commercial, trade, or profit interests, which can... Commission, established by the Help America Vote Act of 2002, 42 U.S.C. 15301 et seq. Commissioner means an... Help America Vote Act of 2002, 42 U.S.C. 15323. Direct costs means those expenditures which the...

11 CFR 9405.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... information for a use or purpose that furthers his/her commercial, trade, or profit interests, which can... Commission, established by the Help America Vote Act of 2002, 42 U.S.C. 15301 et seq. Commissioner means an... Help America Vote Act of 2002, 42 U.S.C. 15323. Direct costs means those expenditures which the...

11 CFR 9405.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... information for a use or purpose that furthers his/her commercial, trade, or profit interests, which can... Commission, established by the Help America Vote Act of 2002, 42 U.S.C. 15301 et seq. Commissioner means an... Help America Vote Act of 2002, 42 U.S.C. 15323. Direct costs means those expenditures which the...

11 CFR 9405.2 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... information for a use or purpose that furthers his/her commercial, trade, or profit interests, which can... Commission, established by the Help America Vote Act of 2002, 42 U.S.C. 15301 et seq. Commissioner means an... Help America Vote Act of 2002, 42 U.S.C. 15323. Direct costs means those expenditures which the...

Publication rates of abstracts presented at the Association of Chiropractic Colleges Educational Conference/Research Agenda Conference from 2002 to 2008

PubMed Central

Bakkum, Barclay W.; Chapman, Cynthia; Johnson, Claire

2014-01-01

Objective The purposes of this study were to investigate the overall publication rates of presentations at the Association of Chiropractic Colleges Educational Conference/Research Agenda Conference (ACC/RAC) meetings (2002–2008), differences in the publication rates of platform vs poster presentations, and the consistency of the meeting abstract compared to the full-length journal article. Methods Abstracts were obtained from proceedings published in the Journal of Chiropractic Education. Literature searches using PubMed and the Index to the Chiropractic Literature (ICL) were performed to locate peer-reviewed journal articles based upon those abstracts. Whether the article was based upon a poster or platform presentation, and the congruence of the information in the abstract and article were recorded. Results We identified 776 proceeding abstracts, 249 of which eventually were published between 2002 and 2012. The overall publication rate was 32.2%. A total of 42.7% of platform presentations eventually were published vs 20.3% of posters. Congruency showed that 43.2% had the same title as the meeting abstract, 59.7% had the same authorship, and 88.8% had the same methods. Conclusion Publication rates of abstracts from spine and orthopedic surgery national meetings range from 34% to 59%. The ACC/RAC meetings have similar publication rates. More platform than poster presentations reach full publication. The congruency of ACC/RAC abstracts to published articles is higher than national meetings in other fields. PMID:24295363

Update on inflation of journal prices: Brandon/Hill list journals and the scientific, technical, and medical publishing market*

PubMed Central

Schlimgen, Joan B.; Kronenfeld, Michael R.

2004-01-01

Objective: The original study of journal prices, using the “Brandon/ Hill Selected List of Books and Journals for the Small Medical Library,” was first published in 1980 and periodically updated. This research continues to measure price increases for these titles for the periods 1996 to 1999 and 1999 to 2002. Methodology: The 111 journal titles that have appeared in each published list from 1967 to 2001 were included in the study. Institutional subscription price data were gathered for each journal for the years 1996, 1999, and 2002 and were compared to the Consumer Price Index (CPI) for the same years. Results: The average journal price continues to rise significantly and is independent of the CPI. The study found that prices have jumped 51.9% from 1996 to 1999 and 32% from 1999 to 2002, which is consistent with nearly every recent journal price study. Conclusion: The unprecedented rise in journal prices negatively affects the purchasing power of medical libraries. This paper examines the economic and technological pressures on the science, technology, and medical journals market that contribute to high prices and identifies a number of initiatives in the biological and health sciences that utilize alternative models for disseminating scientific research. PMID:15243636

Research and trends in science education from 1998 to 2002: a content analysis of publication in selected journals

NASA Astrophysics Data System (ADS)

Tsai, Chin-Chung; Wen, Meichun Lydia

2005-01-01

This study conducted a series of content analyses of the articles published by International Journal of Science Education, Science Education, and Journal of Research in Science Teaching from 1998 to 2002. A total of 802 research papers were analyzed in terms of the authors' nationality, research types and topics. It was found that researchers in four major English-speaking countries, including the US, the UK, Australia, and Canada, contributed to a majority of the publications, but the researchers from other non-English countries may have, to a certain extent, gradually played a valuable role on the published work. This probably implies that science education research may have progressively become an important field recognized by the international academic community. This study also found that most of the published articles were categorized as empirical studies, while position, theoretical and review papers were rarely presented in the journals. Although the research topic of students' conceptions and conceptual change was the most frequently investigated one in these five years, a declining trend was observed when analyzed by year. Moreover, in 1998-2002, the research topics related to student learning contexts, and social, cultural and gender issues were also received relatively more attention among science educators.

Diversity Research in "Teaching of Psychology": Summary and Recommendations

ERIC Educational Resources Information Center

Ocampo, Carlota; Prieto, Loreto R.; Whittlesey, Valerie; Connor, Jane; Janco-Gidley, Julie; Mannix, Sally; Sare, Karen

2003-01-01

We reviewed the body of published research in the journal "Teaching of Psychology" ("ToP") concerning diversity issues (e.g., age, race/ethnicity, gender, national origin, sexual orientation, socioeconomic status). Between 1974 and 2002, approximately 7% of articles published in "ToP" substantively dealt with diversity issues, with gender issues…

Animation Sequence of Comet Wild2 Once More Demonstrates Shape Peculiarities of Small Celestial Bodies

NASA Astrophysics Data System (ADS)

Kochemasov, G. G.

The outstanding success of the Stardust mission having acquired in January 2004 images of Comet Wild2 allows us to compare them with images of some other small objects: satellites, asteroids, comets and confirm the earlier conclusion about prevailing shaping forces [1, 2]. The excellent images of the Comet Wild2 core (the best up to date among comets, Internet) show that it is not ``a ball of dirty ice and rock'' but rather a convexo-concave object resembling other small bodies. They all, independently of their nature, sizes, compositions, demonstrate oblong ``banana''-type style. This is a result of pressing in one side and bulging out another antipodean one (the fundamental wave action). Comet Wild2 (5.4 km long core) in this sense can be perfectly compared with asteroid Mathilde (60 km) and satellite Thebe (˜ 116 km). All three have deeply concave hemisphere opposed by clearly convex one. Bulging out friable material often induces deep fracturing of convex hemispheres. This is well visible in comet Borrelli (8 km long core) and especially pronounced in asteroids Eros (33 km) and Annefrank (`˜ 6 km). Deep ``saddle'' at the convex side of both makes their images rather similar. Another characteristic of small oblong bodies is a principal shape difference of two elongated ends: one is blunt, another sharp. Principally, it is the same process which makes the ``banana''-shape (wave1) but of a smaller scale (wave2). The blunt end is made by pressing in, the sharp end by bulging out. Obviously, an impact sculpturing cannot give similar complex forms in so different bodies. The main principal shaping is done by standing inertia-gravity waves arising in celestial bodies in response to their movement in elliptical orbits with periodically changing accelerations. The fundamental wave1 makes convexo-concave shape, the first overtone wave2 sharp-blunt ends. Larger celestial bodies: satellites, planets, stars react to these waves by universal tectonic dichotomy and sectoring [3]. The arctic-antarctic symptom (after Earth) is typical manifestation of sectoring with two antepodean sectors: one pressed in, another bulged out. References: [1] Kochemasov G.G. (1999) On convexo-concave shape of small celestial bodies // ``Asteroids, Comets, Meteors'' conference, Cornell Univ., U.S.A., July 1999, Abstract # 24. 22; [2] Kochemasov G.G. (2002) ``Dirty snowball'' -- now is too primitive for a scientific description of comets // 34th COSPAR Scientific Assembly at the World Space Congress 2002, 10-19 Oct. 2002, Houston, Texas, USA, (CD-ROM); [3] Kochemasov G.G. (1999) Theorems of wave planetary tectonics // Geophys. Res. Abstr., Vol. 1, # 3, 700.

International Project Management Committee: Overview and Activities

NASA Technical Reports Server (NTRS)

Hoffman, Edward

2010-01-01

This slide presentation discusses the purpose and composition of the International Project Management Committee (IMPC). The IMPC was established by members of 15 space agencies, companies and professional organizations. The goal of the committee is to establish a means to share experiences and best practices with space project/program management practitioners at the global level. The space agencies that are involved are: AEB, DLR, ESA, ISRO, JAXA, KARI, and NASA. The industrial and professional organizational members are Comau, COSPAR, PMI, and Thales Alenia Space.

Prebiotic chemistry in space; Proceedings of Symposia B1.4 and F3.3 of the COSPAR Scientific Assembly, 30th, Hamburg, Germany, July 11-21, 1994

NASA Technical Reports Server (NTRS)

1994-01-01

A two-part symposium was held concerning topics in Solar System chemistry. The first part covered the organic chemistry ofsmall bodies of the interplanetray medium. It produced papers on the evolution, spectral properties and composition of organic matter in comets, interplanetary dust and asteroids. The second part covered cryochemistry and exobiology in planetary atmospheres (gas giant planets and their satellites) and in various astronomical ices.

Proceedings of Workshop 15 of the COSPAR Meetings Held in Toulouse, France on 30 June-12 July 1986. Chapter 2. Reference Atmospheres and Thermospheric Mapping,

DTIC Science & Technology

1988-01-21

DISTRIBUTION/AVAILABILITY OF REPORT Approved for public release; 2b. DECLASSIFICATION /’DOWNGRADING SCHEDULE Distribution unlimited 4. PERFORMING ORGANIZATION ...REPORT NUMBER(S) 5. MONITORING ORGANIZATION REPORT NUMBER(S) AFGL-TR-88-0016 6a, NAME OF PERFORMING ORGANIZATION 6b. OFFICE SYMBOL 7a. NAME OF...MONITORING ORGANIZATION Air Force Geophysics (If applicable) Laboratory I oc. ADDRESS (City, State, and ZIP Code) 7b ADDRESS (City, Stare, and ZIP Code

Near-earth radiation environment including time variations and secondary radiation; Meetings F2.6 and F2.7, COSPAR Scientific Assembly, 30th, Hamburg, Germany, July 11-21, 1994

NASA Technical Reports Server (NTRS)

Shea, M. A. (Editor); Heinrich, W. (Editor); Badhwar, G. D. (Editor)

1996-01-01

Both man and technological equipment must survive the near-earth space radiation environment, which can, under specific conditions, be extremely severe. This conference produced 17 papers on the dynamic space radiation environment covering: galactic, solar and trapped particles; nuclear fragmentation; nuclear interactions and transport theory; solar proton events; radiation shielding; and heavy ion fluences. Several papers present results from the recent SAMPEX mission.

The Conventional Armed Forces in Europe Treaty and Its Contribution to Euro-Atlantic Security After 1990

DTIC Science & Technology

2005-06-01

37. 120 Ibid., 259. 121 Ibid., 258. 122 Ibid., 54. 123 Ibid., 55. 124 Anne C. Aldis and Roger N. McDermott, Russian Military Reform 1992-2002...61 BIBLIOGRAPHY Aldis, Anne C. and Roger N. McDermott. Russian Military Reform 1992-2002. London: Frank Cass, 2003. Altmann, Jürgen, Henny

5 CFR 430.401 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Law 107-296, the Homeland Security Act of 2002; November 25, 2002), which provides a higher aggregate... calendar year up to the rate for level I of the Executive Schedule under 5 U.S.C. 5307(a) and 5 CFR 530.203... Performance Appraisal Certification for Pay Purposes § 430.401 Purpose. (a) This subpart implements 5 U.S.C...

Antibiotic susceptibility in Streptococcus pneumoniae, Haemophilus influenzae and Streptococcus pyogenes in Pakistan: a review of results from the Survey of Antibiotic Resistance (SOAR) 2002-15.

PubMed

Zafar, A; Hasan, R; Nizamuddin, S; Mahmood, N; Mukhtar, S; Ali, F; Morrissey, I; Barker, K; Torumkuney, D

2016-05-01

To investigate changes in the antibiotic susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Streptococcus pyogenes from the Survey of Antibiotic Resistance (SOAR) in community-acquired respiratory tract infections (CA-RTIs) between 2002 and 2015 in Pakistan. This is a review based on previously published studies from 2002-03, 2004-06 and 2007-09 and also new data from 2014-15. Susceptibility was determined by Etest(®) or disc diffusion according to CLSI and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints. A total of 706 isolates from CA-RTIs comprising 381 S. pneumoniae, 230 H. influenzae and 95 S. pyogenes were collected between 2002 and 2015 and tested against a range of antibiotics. Antibiotic resistance in S. pneumoniae rose steeply from 2002 to 2009, with isolates non-susceptible to penicillin and macrolides increasing from 10% to 34.1% and from 13%-14% to 29.7%, respectively. Susceptibility to amoxicillin/clavulanic acid (and by inference amoxicillin) remained between 99.4% and 100% from 2002 to 2015. Over the years, the prevalence of susceptibility to cefuroxime was 98%-100% among S. pneumoniae. Resistance in S. pneumoniae to some older antibiotics between 2007 and 2009 was high (86.8% for trimethoprim/sulfamethoxazole and 57.2% for tetracycline). Between 2002 and 2015, ampicillin resistance (β-lactamase-positive strains) among H. influenzae has remained low (between 2.6% and 3.2%) and almost unchanged over the years (H. influenzae was not tested during 2004-06). For S. pyogenes isolates, macrolide resistance reached 22%; however, susceptibility to penicillin, amoxicillin/clavulanic acid and cefuroxime remained stable at 100%. In S. pneumoniae from Pakistan, there has been a clear reduction in susceptibility to key antibiotics since 2002, but not to amoxicillin/clavulanic acid (amoxicillin) or cefuroxime. However, susceptibility in H. influenzae has remained stable. Local antibiotic susceptibility/resistance data are essential to support informed prescribing for CA-RTIs and other infections. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Search at BaBar for D^0--\\overlineD^0 Mixing using Semileptonic Decays.

NASA Astrophysics Data System (ADS)

Flood, Kevin

2004-05-01

Based on a 87 fb-1 dataset acquired by the Babar experiment running on and near the Υ(4S) from 1999-2002, a new upper limit is set on the rate of D^0--\\overlineD^0 mixing using the decay modes D^*+ arrow π^+ D^0, D^0 arrow [K / K^*]eν (+c.c.). These modes offer unambiguous initial and final-state charm flavor tags, and allow the combined use of the D^0 lifetime and D^*+--D^0 mass difference (Δ M) in a global likelihood fit. The high-statistics sample of reconstructed unmixed semileptonic D^0 decays is used to model Δ M and the time-dependence of mixed events directly from the data. Neural networks are used both to select events and to fully reconstruct the D^0. The current world-best published limit on semileptonic charm mixing is 5x10-3 (90% C.L.) (E791).

Modeling of Anaerobic Digestion with a Focus on Estimation of Hydrolysis Constants at 35, 55, and 60 °C.

PubMed

Haghighatafshar, Salar; Ossiansson, Elin; Koch, Konrad; Kjerstadius, Hamse; Jansen, Jes la Cour; Davidsson, Åsa

2015-07-01

Hydrolysis constants of mixed sludge at 35, 55, and 60 °C were found to be 0.32, 0.44, and 0.50 1/d, respectively, in pilot-scale, semicontinuously operated anaerobic digesters. The hydrolysis constants and estimated chemical oxygen demand fractions in the feed were introduced to a mathematical model for anaerobic digestion published by Siegrist et al. (2002), which is similar to Anaerobic Digestion Model No. 1. First-order and Monod-type kinetics were tested for estimation of hydrolysis constants. The applied kinetics were found to affect the outcome of the regression study. Moreover, the free ammonia inhibition model was excluded for both propionate oxidation and acetate conversion, thanks to the apparent acclimatized biomass. No substantial accumulation of volatile fatty acids was observed in the reactors at 35, 55, and 60 °C, corresponding to free ammonia nitrogen concentrations of about 20, 110, and 130 g N/m³, respectively.

Birth, Bath, and Beyond: The Science and Safety of Water Immersion During Labor and Birth

PubMed Central

Harper, Barbara

2014-01-01

The 2014 objection to birth in water voiced by both the American Academy of Pediatrics and the American College of Obstetricians and Gynecologists (ACOG) in ACOG Bulletin #594 on immersion in water during labor and birth is nothing new. The Committee on Fetus and Newborn published the very same opinion in 2005, based on a case report that was published in 2002 in the journal Pediatrics. What has changed since 2002 is a growing body of evidence that reports on the safety and efficacy of labor and birth in water. This article reviews the retrospective literature on water birth and explains newborn physiology and the protective mechanisms that prevent babies from breathing during a birth in water. PMID:25364216

NREL: News - Advisor 2002-A Powerful Vehicle Simulation Tool Gets Better

Science.gov Websites

Advisor 2002-A Powerful Vehicle Simulation Tool Gets Better Golden, Colo., June 11, 2002 A powerful analysis is made possible by co-simulation links to Avant!'s Saber and Ansoft's SIMPLORER�. Transient air conditioning system analysis is possible by co-simulation with C&R Technologies' SINDA/FLUINT

Genetic recombination of the hepatitis C virus: clinical implications.

PubMed

Morel, V; Fournier, C; François, C; Brochot, E; Helle, F; Duverlie, G; Castelain, S

2011-02-01

Genetic recombination is a well-known feature of RNA viruses that plays a significant role in their evolution. Although recombination is well documented for Flaviviridae family viruses, the first natural recombinant strain of hepatitis C virus (HCV) was identified as recently as 2002. Since then, a few other natural inter-genotypic, intra-genotypic and intra-subtype recombinant HCV strains have been described. However, the frequency of recombination may have been underestimated because not all known HCV recombinants are screened for in routine practice. Furthermore, the choice of treatment regimen and its predictive outcome remain problematic as the therapeutic strategy for HCV infection is genotype dependent. HCV recombination also raises many questions concerning its mechanisms and effects on the epidemiological and physiopathological features of the virus. This review provides an update on recombinant HCV strains, the process that gives rise to recombinants and clinical implications of recombination. © 2010 Blackwell Publishing Ltd.

Review of Recent Research (2002-2008) on Applied Linguistics and Language Teaching with Specific Reference to L2 German (Part 1)

ERIC Educational Resources Information Center

Eckerth, Johannes; Schramm, Karen; Tschirner, Erwin

2009-01-01

This review of research on the learning, teaching, and assessment of L2 German published or completed between 2002 and 2008 may be particularly timely due to developments from within the profession as well as recent political changes which continue to have a strong bearing on the way L2 German is promoted, learned, taught and assessed. Far from…

Effects of air velocity on photosynthesis of plant canopies under elevated CO2 levels in a plant culture system.

PubMed

Kitaya, Y; Shibuya, T; Yoshida, M; Kiyota, M

2004-01-01

To obtain basic data for adequate air circulation for promoting plant growth in closed plant production modules in bioregenerative life support systems in space, effects of air velocities ranging from 0.1 to 0.8 m s-1 on photosynthesis in tomato seedlings canopies were investigated under atmospheric CO2 concentrations of 0.4 and 0.8 mmol mol-1. The canopy of tomato seedlings on a plug tray (0.4 x 0.4 m2) was set in a wind-tunnel-type chamber (0.6 x 0.4 x 0.3 m3) installed in a semi-closed-type assimilation chamber (0.9 x 0.5 x 0.4 m3). The net photosynthetic rate in the plant canopy was determined with the differences in CO2 concentrations between the inlet and outlet of the assimilation chamber multiplied by the volumetric air exchange rate of the chamber. Photosynthetic photon flux (PPF) on the plant canopy was kept at 0.25 mmol m-2 s-1, air temperature at 23 degrees C and relative humidity at 55%. The leaf area indices (LAIs) of the plant canopies were 0.6-2.5 and plant heights were 0.05-0.2 m. The net photosynthetic rate of the plant canopy increased with increasing air velocities inside plant canopies and saturated at 0.2 m s-1. The net photosynthetic rate at the air velocity of 0.4 m s-1 was 1.3 times that at 0.1 m s-1 under CO2 concentrations of 0.4 and 0.8 mmol mol-1. The net photosynthetic rate under CO2 concentrations of 0.8 mmol mol-1 was 1.2 times that under 0.4 mmol mol-1 at the air velocity ranging from 0.1 to 0.8 m s-1. The results confirmed the importance of controlling air movement for enhancing the canopy photosynthesis under an elevated CO2 level as well as under a normal CO2 level in the closed plant production modules. c2004 COSPAR. Published by Elsevier Ltd. All rights reserved.

In vivo and in vitro measurements of complex-type chromosomal exchanges induced by heavy ions.

PubMed

George, K; Durante, M; Wu, H; Willingham, V; Cucinotta, F A

2003-01-01

Heavy ions are more efficient in producing complex-type chromosome exchanges than sparsely ionizing radiation, and this can potentially be used as a biomarker of radiation quality. We measured the induction of complex-type chromosomal aberrations in human peripheral blood lymphocytes exposed in vitro to accelerated H-, He-, C-, Ar-, Fe- and Au-ions in the LET range of approximately 0.4-1400 keV/micrometers. Chromosomes were analyzed either at the first post-irradiation mitosis, or in interphase, following premature condensation by phosphatase inhibitors. Selected chromosomes were then visualized after FISH-painting. The dose-response curve for the induction of complex-type exchanges by heavy ions was linear in the dose-range 0.2-1.5 Gy, while gamma-rays did not produce a significant increase in the yield of complex rearrangements in this dose range. The yield of complex aberrations after 1 Gy of heavy ions increased up to an LET around 100 keV/micrometers, and then declined at higher LET values. When mitotic cells were analyzed, the frequency of complex rearrangements after 1 Gy was about 10 times higher for Ar- or Fe- ions (the most effective ions, with LET around 100 keV/micrometers) than for 250 MeV protons, and values were about 35 times higher in prematurely condensed chromosomes. These results suggest that complex rearrangements may be detected in astronauts' blood lymphocytes after long-term space flight, because crews are exposed to HZE particles from galactic cosmic radiation. However, in a cytogenetic study of ten astronauts after long-term missions on the Mir or International Space Station, we found a very low frequency of complex rearrangements, and a significant post-flight increase was detected in only one out of the ten crewmembers. It appears that the use of complex-type exchanges as biomarker of radiation quality in vivo after low-dose chronic exposure in mixed radiation fields is hampered by statistical uncertainties. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

Surface ocean carbon isotope anomalies on glacial terminations: An alternative view

NASA Astrophysics Data System (ADS)

Lund, D. C.; Cote, M.; Schmittner, A.

2016-12-01

Late Pleistocene glacial terminations are characterized by surface ocean carbon isotope minima on a global scale. During the last deglaciation (i.e. Termination 1), planktonic foraminiferal δ13C anomalies occurred in the Atlantic, Indian, Pacific, and Southern Oceans. Despite the apparently ubiquitous nature of δ13C anomalies on glacial terminations, their cause remains a matter of ongoing debate. The prevailing view is that isotopically light carbon from the abyss was upwelled in the Southern Ocean, resulting in outgassing of 13C-depleted carbon to the atmosphere and its advection to lower latitudes via mode and intermediate waters (Spero and Lea, 2002). Alternatively, carbon isotope minima may be driven by weakening of the biological pump related to circulation-driven changes in the oceanic preformed nutrient budget (Schmittner and Lund, 2015). Here we assess the deep upwelling and biological pump hypotheses using a new compilation of 70 globally-distributed planktonic δ13C records from the published literature. We find that 1) the mean deglacial δ13C anomaly is similar in all ocean basins, 2) the eastern tropical Pacific yields smaller mean δ13C anomalies than the western tropical Pacific, and 3) δ13C anomalies in the Southern Ocean decrease with increasing latitude. Our results are generally inconsistent with the deep upwelling hypothesis, which predicts that the δ13C signal should be largest in the Southern Ocean and upwelling regions. Instead, the spatial pattern in δ13C anomalies supports the biological pump hypothesis, which predicts that reduced export of light carbon from the euphotic zone triggers negative carbon isotope anomalies in the surface ocean and positive anomalies at intermediate depths. Upwelling of relatively 13C-enriched intermediate waters tends to moderate carbon isotope minima in upwelling regions. Our results suggest that the initial rise in atmospheric CO2 during Termination 1 was likely due to weakening of the biological pump associated with a reduction in the Atlantic Meridional Overturning Circulation, consistent with model results (Schmittner and Lund, 2015). Spero, H., and D. Lea (2002) Science 296, 522-525. Schmittner, A., and D. Lund (2015) Climate of the Past 11, 135-152.

Naming Institutionalized Racism in the Public Health Literature: A Systematic Literature Review.

PubMed

Hardeman, Rachel R; Murphy, Katy A; Karbeah, J'Mag; Kozhimannil, Katy Backes

Although a range of factors shapes health and well-being, institutionalized racism (societal allocation of privilege based on race) plays an important role in generating inequities by race. The goal of this analysis was to review the contemporary peer-reviewed public health literature from 2002-2015 to determine whether the concept of institutionalized racism was named (ie, explicitly mentioned) and whether it was a core concept in the article. We used a systematic literature review methodology to find articles from the top 50 highest-impact journals in each of 6 categories (249 journals in total) that most closely represented the public health field, were published during 2002-2015, were US focused, were indexed in PubMed/MEDLINE and/or Ovid/MEDLINE, and mentioned terms relating to institutionalized racism in their titles or abstracts. We analyzed the content of these articles for the use of related terms and concepts. We found only 25 articles that named institutionalized racism in the title or abstract among all articles published in the public health literature during 2002-2015 in the 50 highest-impact journals and 6 categories representing the public health field in the United States. Institutionalized racism was a core concept in 16 of the 25 articles. Although institutionalized racism is recognized as a fundamental cause of health inequities, it was not often explicitly named in the titles or abstracts of articles published in the public health literature during 2002-2015. Our results highlight the need to explicitly name institutionalized racism in articles in the public health literature and to make it a central concept in inequities research. More public health research on institutionalized racism could help efforts to overcome its substantial, longstanding effects on health and well-being.

Caldicellulosiruptor kronotskyensis sp. nov. and Caldicellulosiruptor hydrothermalis sp. nov., two extremely thermophilic, cellulolytic, anaerobic bacteria from Kamchatka thermal springs.

PubMed

Miroshnichenko, Margarita L; Kublanov, Ilya V; Kostrikina, Nadezhda A; Tourova, Tatyana P; Kolganova, Tatyana V; Birkeland, Nils-Kåre; Bonch-Osmolovskaya, Elizaveta A

2008-06-01

Five novel strains (2002(T), 2902, 2006, 108(T) and 117) of cellulose-degrading, anaerobic, thermophilic bacteria were isolated from terrestrial hot springs of Kamchatka (Far East, Russia). Strains 2002(T) and 108(T) were non-spore-forming bacteria with a Gram-positive type cell wall and peritrichous flagella. Optimum growth of strains 2002(T) and 108(T) occurred at pH 7.0 and at temperatures of 70 and 65 degrees C, respectively. The G+C contents of the DNA of strains 2002(T) and 108(T) were 35.1 and 36.4 mol%, respectively. Comparative 16S rRNA gene sequence analysis revealed that the isolates belonged to the genus Caldicellulosiruptor. However, DNA-DNA hybridization experiments indicated that the levels of relatedness between strains 2002(T) and 108(T) and those of recognized members of the genus Caldicellulosiruptor ranged between 32 and 54 %. Based on both phenotypic and genomic differences, strains 2002(T) and 108(T) are considered to represent two novel species of the genus Caldicellulosiruptor. The names proposed for these organisms are Caldicellulosiruptor kronotskyensis sp. nov. (type strain 2002(T)=DSM 18902(T)=VKM B-2412(T)) and Caldicellulosiruptor hydrothermalis sp. nov. (type strain 108(T)=DSM 18901(T)=VKM B-2411(T)).

Publishing in "SERJ": An Analysis of Papers from 2002-2009

ERIC Educational Resources Information Center

Zieffler, Andrew; Garfield, Joan; delMas, Robert C.; Le, Laura; Isaak, Rebekah; Bjornsdottir, Audbjorg; Park, Jiyoon

2011-01-01

"SERJ" has provided a high quality professional publication venue for researchers in statistics education for close to a decade. This paper presents a review of the articles published to explore what they suggest about the field of statistics education, the researchers, the questions addressed, and the growing knowledge base on teaching and…

Thermal infrared and optical photometry of Asteroidal Comet C/2002 CE10

NASA Astrophysics Data System (ADS)

Sekiguchi, Tomohiko; Miyasaka, Seidai; Dermawan, Budi; Mueller, Thomas; Takato, Naruhisa; Watanabe, Junichi; Boehnhardt, Hermann

2018-04-01

C/2002 CE10 is an object in a retrograde elliptical orbit with Tisserand parameter - 0.853 indicating a likely origin in the Oort Cloud. It appears to be a rather inactive comet since no coma and only a very weak tail was detected during the past perihelion passage. We present multi-color optical photometry, lightcurve and thermal mid-IR observations of the asteroidal comet. With the photometric analysis in BVRI, the surface color is found to be redder than asteroids, corresponding to cometary nuclei and TNOs/Centaurs. The time-resolved differential photometry supports a rotation period of 8.19 ± 0.05 h. The effective diameter and the geometric albedo are 17.9 ± 0.9 km and 0.03 ± 0.01, respectively, indicating a very dark reflectance of the surface. The dark and redder surface color of C/2002 CE10 may be attribute to devolatilized material by surface aging suffered from the irradiation by cosmic rays or from impact by dust particles in the Oort Cloud. Alternatively, C/2002 CE10 was formed of very dark refractory material originally like a rocky planetesimal. In both cases, this object lacks ices (on the surface at least). The dynamical and known physical characteristics of C/2002 CE10 are best compatible with those of the Damocloids population in the Solar System, that appear to be exhaust cometary nucleus in Halley-type orbits. The study of physical properties of rocky Oort cloud objects may give us a key for the formation of the Oort cloud and the solar system.

The bees of the genus Colletes Latreille 1802 of the European part of Russia, with keys to species (Hymenoptera: Apoidea: Colletidae).

PubMed

Kuhlmann, Michael; Proshchalykin, Maxim Yu

2014-10-24

For the European part of Russia 30 species of the bee genus Colletes are recorded. Colletes subnitens Noskiewicz 1936, C. wacki Kuhlmann 2002 and C. warnckei Kuhlmann 2002 were found in Russia for the first time and C. kozlovi Friese 1913 is newly recorded from the European part of Russia. For Colletes kozlovi, C. subnitens and C. wacki this is the first record for Europe. The female of C. subnitens Noskiewicz is here described for the first time. Illustrated keys to males and females of all species known from European part of Russia are provided.

Volume and methodological quality of randomized controlled trials in laparoscopic surgery: assessment over a 10-year period.

PubMed

Antoniou, Stavros A; Andreou, Alexandros; Antoniou, George A; Koch, Oliver O; Köhler, Gernot; Luketina, Ruzica-R; Bertsias, Antonios; Pointner, Rudolph; Granderath, Frank-Alexander

2015-11-01

Measures have been taken to improve methodological quality of randomized controlled trials (RCTs). This review systematically assessed the trends in volume and methodological quality of RCTs on minimally invasive surgery within a 10-year period. RCTs on minimally invasive surgery were searched in the 10 most cited general surgical journals and the 5 most cited journals of laparoscopic interest for the years 2002 and 2012. Bibliometric and methodological quality components were abstracted using the Scottish Intercollegiate Guidelines Network. The pooled number of RCTs from low-contribution regions demonstrated an increasing proportion of the total published RCTs, compensating for a concomitant decrease of the respective contributions from Europe and North America. International collaborations were more frequent in 2012. Acceptable or high quality RCTs accounted for 37.9% and 54.4% of RCTs published in 2002 and 2012, respectively. Components of external validity were poorly reported. Both the volume and the reporting quality of laparoscopic RCTs have increased from 2002 to 2012, but there seems to be ample room for improvement of methodological quality. Copyright © 2015 Elsevier Inc. All rights reserved.

Innovative financing instruments for global health 2002-15: a systematic analysis.

PubMed

Atun, Rifat; Silva, Sachin; Knaul, Felicia M

2017-07-01

Development assistance for health (DAH), the value of which peaked in 2013 and fell in 2015, is unlikely to rise substantially in the near future, increasing reliance on domestic and innovative financing sources to sustain health programmes in low-income and middle-income countries. We examined innovative financing instruments (IFIs)-financing schemes that generate and mobilise funds-to estimate the quantum of financing mobilised from 2002 to 2015. We identified ten IFIs, which mobilised US$8·9 billion (2·3% of overall DAH) in 2002-15. The funds generated by IFIs were channelled mostly through GAVI and the Global Fund, and used for programmes for new and underused vaccines, HIV/AIDS, malaria, tuberculosis, and maternal and child health. Vaccination programmes received the largest amount of funding ($2·6 billion), followed by HIV/AIDS ($1080·7 million) and malaria ($1028·9 million), with no discernible funding targeted to non-communicable diseases. Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. Published by Elsevier Ltd.. All rights reserved.

What are seasonal and meteorological factors are associated with the number of attendees at a sexual health service? An observational study between 2002-2012.

PubMed

Gamagedara, Nimal; Hocking, Jane S; Law, Mathew; Fehler, Glenda; Chen, Marcus Y; Bradshaw, Catriona S; Fairley, Christopher K

2014-12-01

Open access to sexual health services may be inefficient if there are substantial unpredictable fluctuations in presentations. Our aim was to determine whether the number of presentations over the last 11 years was associated with certain factors. This study involved all individuals presenting to Melbourne Sexual Health Centre (MSHC) from 2002 to 2012. The outcome measure was the number of presentations during a clinical session (half day). There were 270,070 presentations to the clinic among 86,717 individuals. The factors associated with the largest difference in mean presentations per session were morning or afternoon (60 vs 51 per session), days of the week (57-67 per session), months of the year (93-112 per day), year (77-131 per day), maximum temperatures of <15 °C vs. ≥30 °C (56-62 per morning session) and 5 working days after holiday periods (61 vs 54). A multiple linear regression model using these factors explained 64% of the variation in attendances per session. Peak attendance rates (>90th centile) were also strongly correlated with these same variables. Higher-risk heterosexuals (≤25 years of age) attended more commonly in the afternoons (37% of heterosexuals) than in the mornings (30%). No factor other than year of attendance substantially influenced the proportion of higher-risk men who have sex with men (MSM) (≥10 partners per year) who attended. A considerable proportion of the variability in presentations was explained by known factors that could predict client presentations to sexual health services and therefore allow optimal allocation of resources to match demand. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Aquatic modules for bioregenerative life support systems: developmental aspects based on the space flight results of the C.E.B.A.S. MIN-MODULE.

PubMed

Blum, V

2003-01-01

The Closed Equilibrated Biological Aquatic System (C.E.B.A.S.) is an artificial aquatic ecosystem which contains teleost fishes, water snails, ammonia oxidizing bacteria and edible non-gravitropic water plants. It serves as a model for aquatic food production modules which are not seriously affected by microgravity and other space conditions. Its space flight version, the so-called C.E.B.A.S. MINI-MODULE was already successfully tested in the STS-89 and STS-90 (NEUROLAB) missions. It will be flown a third time in space with the STS-107 mission in January 2003. All results obtained so far in space indicate that the basic concept of the system is more than suitable to drive forward its development. The C.E.B.A.S. MINI-MODULE is located within a middeck locker with limited space for additional components. These technical limitations allow only some modifications which lead to a maximum experiment time span of 120 days which is not long enough for scientifically essential multi-generation-experiments. The first necessary step is the development of "harvesting devices" for the different organisms. In the limited space of the plant bioreactor a high biomass production leads to self-shadowing effects which results in an uncontrolled degradation and increased oxygen consumption by microorganisms which will endanger the fishes and snails. It was shown already that the latter reproduce excellently in space and that the reproductive functions of the fish species are not affected. Although the parent-offspring-cannibalism of the ovoviviparous fish species (Xiphophorus helleri) serves as a regulating factor in population dynamics an uncontrolled snail reproduction will also induce an increased oxygen consumption per se and a high ammonia concentration in the water. If harvesting locks can be handled by astronauts in, e. g., 4-week intervals their construction is not very difficult and basic technical solutions are already developed. The second problem is the feeding of the animals. Although C.E.B.A.S.-based aquaculture modules are designed to be closed food loop systems (edible herbivorous fish species and edible water plants) which are already verified on Earth this will not be possible in space without devices in which the animals are fed from a food storage. This has to be done at least once daily which would waste too much crew time when done by astronauts. So, the development of a reliable automated food dispenser has highest priority. Also in this case basic technical solutions are already elaborated. The paper gives a comprehensive overview of the proposed further C.E.B.A.S.-based development of longer-term duration aquatic food production modules. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

On transient events in the upper atmosphere generated away of thunderstorm regions

NASA Astrophysics Data System (ADS)

Morozenko, V.; Garipov, G.; Khrenov, B.; Klimov, P.; Panasyuk, M.; Sharakin, S.; Zotov, M.

2011-12-01

Experimental data on transient events in UV and Red-IR ranges obtained in the MSU missions "Unversitetsky-Tatiana" (wavelengths 300-400 nm) and "Unversitetsky-Tatiana-2" (wavelengths 300-400 nm and 600-800 nm), published by Garipov et al, in 2010 at COSPAR session http://www.cospar2010.org, at TEPA conference http://www.aragats.am/Conferences/tepa2010 and in 2011 by Sadovnichy et al, Solar System Research, 45, #1, 3-29 (2011); Vedenkin et al, JETP, v. 140, issue 3(9), 1-11 (2011) demonstrated existence of transients at large distances (up to thousands km) away of cloud thunderstorm regions. Those "remote" transients are short (1-5 msec) and are less luminous than the transients above thunderstorm regions. The ratio of Red-IR to UV photon numbers in those transients indicates high altitude of their origin (~70 km). Important observation facts are also: 1. a change of the exponent in transient distribution on luminosity Q ("-1" for photon numbers Q=1020 -1023 to "-2" for Q>1023), 2. a change of global distribution of transient with their luminosity (transients with Q>1023 are concentrated in equatorial range above continents, while transients with low luminosity are distributed more uniformly), 3. a phenomenon of transient sequences in one satellite orbit which is close to geomagnetic meridian. In the present paper phenomenological features of transients are explained in assumption that the observed transients have to be divided in two classes: 1. transients related to local, lower in the atmosphere, lightning at distance not more than hundreds km from satellite detector field of view in the atmosphere and 2. transients generated by far away lightning. Local transients are luminous and presumably are events called "transient luminous events" (TLE). In distribution on luminosity those events have some threshold Q~1023 and their differential luminosity distribution is approximated by power law exponent "-2". Remote transients have to be considered separately. Their origin may be related to electromagnetic pulses (EMP) or waves (whistler, EMW) generated by lightning. The EMP-EMW is transmitted in the ionosphere- ground channel to large distances R with low absorption. The part of EMP-EMW "visible" in the detector aperture diminishes with distance as R-1 due to observation geometry. The EMP-EMW triggers the electric discharge in the upper atmosphere (lower ionosphere, ~70 km). Estimates of resulting transients luminosity and their correlation with geomagnetic field are in progress.

Duck Valley Habitat Enhancement and Protection, 2001-2002 Progress Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allen, Mattie H.; Sellman, Jake

The Duck Valley Indian Reservation's Habitat Enhancement project is an ongoing project designed to enhance and protect critical riparian areas, natural springs, the Owhyee River and its tributaries, and native fish spawning areas on the Reservation. The project commenced in 1997 and addresses the Northwest Power Planning Council's measures 10.8C.2, 10.8C.3, and 10.8C.5 of the 1994 Columbia River Basin Fish and Wildlife Program. The performance period covers dates from April 2001 through August 2002.

26 CFR 1.221-2 - Deduction for interest due and paid on qualified education loans before January 1, 2002.

Code of Federal Regulations, 2011 CFR

2011-04-01

... education loans before January 1, 2002. 1.221-2 Section 1.221-2 Internal Revenue INTERNAL REVENUE SERVICE... VII and VIII of the Public Health Service Act (42 U.S.C. 292., and 42 U.S.C. 296)) under applicable... performance of services in certain occupations or federal programs, and the borrower satisfies one of those...

NATO-Russian Relations: Status and Prospectives

DTIC Science & Technology

2004-12-01

commission to draft it until July 1994. 91 Anne C. Aldis and Roger N. McDermott, Russian Military Reform 1992... Russian Military Reform 1992-2002, p. 4. 42 Finally, the President signed the first National Security Concept of the Russian Federation on 17 December...INTENTIONALLY LEFT BLANK 73 LIST OF REFERENCES Aldis, Anne C. and McDermott, Roger N., Russian Military Reform 1992-2002, (Portland, OR: Conflict

Phylogenetic analysis of HIV-1 reverse transcriptase sequences from 382 patients recruited in JJ Hospital of Mumbai, India, between 2002 and 2008.

PubMed

Deshpande, Alaka; Jauvin, Valerie; Pinson, Patricia; Jeannot, Anne Cecile; Fleury, Herve J

2009-06-01

Analysis of reverse transcriptase (RT) sequences of 382 HIV-1 isolates from untreated and treated patients recruited in JJ Hospital (Mumbai, India) between 2002 and 2008 shows that subtype C is largely predominant (98%) and that non-C sequences cluster with A1, B, CRF01_AE, and CRF06_cpx.

Pallet industry relying more on recovered wood material

Treesearch

J. Bejune; R. Bush; Philip A. Araman; B. Hansen; D. Cumbo

2002-01-01

This article is a research report titled, Wood Use Trends in the Pallet and Container Industry: 1992 - 1999, that was published by the authors earlier this year. The research was conducted by Virginia Tech in collaboration with the U.S. Forest Service Southern Research Station. Part one, published in the September, 2002 issue of Pallet Enterprise, summarized the...

Advanced nutrient root-feeding system for conveyor-type cylindrical plant growth facilities for microgravity.

PubMed

Berkovich, Yu A; Krivobok, N M; Krivobok, A S; Smolyanina, S O

2016-02-01

A compact and reliable automatic method for plant nutrition supply is needed to monitor and control space-based plant production systems. The authors of this study have designed a nutrient root-feeding system that minimizes and regulates nutrient and water supply without loss of crop yields in a space greenhouse. The system involves an ion-exchange fibrous artificial soil (AS) BIONA-V3(TM) as the root-inhabited medium; a pack with slow-release fertilizer as the main source of nitrogen, phosphorus, and potassium; and a cartridge with granular mineral-rich ionite (GMRI) as a source of calcium, magnesium, sulfur, and iron. A controller equipped with an electrical conductivity meter controls the solution flow and concentration of the solution in the mixing tank at specified values. Experiments showed that the fibrous AS-stabilized pH of the substrate solution within the range of 6.0-6.6 is favorable to the majority of crops. The experimental data confirmed that this technique allowed solution preparation for crops in space greenhouses by means of pumping water through the cartridge and minimization of the AS stock onboard the space vehicle. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Developmental, nutritional and hormonal anomalies of weightlessness-grown wheat.

PubMed

Carman, J G; Hole, P; Salisbury, F B; Bingham, G E

2015-07-01

The behavior of water in weightlessness, as occurs in orbiting spacecraft, presents multiple challenges for plant growth. Soils remain saturated, impeding aeration, and leaf surfaces remain wet, impeding gas exchange. Herein we report developmental and biochemical anomalies of "Super Dwarf" wheat (Triticum aestivum L.) grown aboard Space Station Mir during the 1996-97 "Greenhouse 2" experiment. Leaves of Mir-grown wheat were hyperhydric, senesced precociously and accumulated aromatic and branched-chain amino acids typical of tissues experiencing oxidative stress. The highest levels of stress-specific amino acids occurred in precociously-senescing leaves. Our results suggest that the leaf ventilation system of the Svet Greenhouse failed to remove sufficient boundary layer water, thus leading to poor gas exchange and onset of oxidative stress. As oxidative stress in plants has been observed in recent space-flight experiments, we recommend that percentage water content in apoplast free-spaces of leaves be used to evaluate leaf ventilation effectiveness. Mir-grown plants also tillered excessively. Crowns and culms of these plants contained low levels of abscisic acid but high levels of cytokinins. High ethylene levels may have suppressed abscisic acid synthesis, thus permitting cytokinins to accumulate and tillering to occur. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Simulation of the GCR spectrum in the Mars curiosity rover's RAD detector using MCNP6.

PubMed

Ratliff, Hunter N; Smith, Michael B R; Heilbronn, Lawrence

2017-08-01

The paper presents results from MCNP6 simulations of galactic cosmic ray (GCR) propagation down through the Martian atmosphere to the surface and comparison with RAD measurements made there. This effort is part of a collaborative modeling workshop for space radiation hosted by Southwest Research Institute (SwRI). All modeling teams were tasked with simulating the galactic cosmic ray (GCR) spectrum through the Martian atmosphere and the Radiation Assessment Detector (RAD) on-board the Curiosity rover. The detector had two separate particle acceptance angles, 4π and 30 ° off zenith. All ions with Z = 1 through Z = 28 were tracked in both scenarios while some additional secondary particles were only tracked in the 4π cases. The MCNP6 4π absorbed dose rate was 307.3 ± 1.3 µGy/day while RAD measured 233 µGy/day. Using the ICRP-60 dose equivalent conversion factors built into MCNP6, the simulated 4π dose equivalent rate was found to be 473.1 ± 2.4 µSv/day while RAD reported 710 µSv/day. Copyright © 2017 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Measurements of the neutron spectrum in transit to Mars on the Mars Science Laboratory.

PubMed

Köhler, J; Ehresmann, B; Zeitlin, C; Wimmer-Schweingruber, R F; Hassler, D M; Reitz, G; Brinza, D E; Appel, J; Böttcher, S; Böhm, E; Burmeister, S; Guo, J; Lohf, H; Martin, C; Posner, A; Rafkin, S

2015-04-01

The Mars Science Laboratory spacecraft, containing the Curiosity rover, was launched to Mars on 26 November 2011. Although designed for measuring the radiation on the surface of Mars, the Radiation Assessment Detector (RAD) measured the radiation environment inside the spacecraft during most of the 253-day, 560-million-kilometer cruise to Mars. An important factor for determining the biological impact of the radiation environment inside the spacecraft is the specific contribution of neutrons with their high biological effectiveness. We apply an inversion method (based on a maximum-likelihood estimation) to calculate the neutron and gamma spectra from the RAD neutral particle measurements. The measured neutron spectrum (12-436 MeV) translates into a radiation dose rate of 3.8±1.2 μGy/day and a dose equivalent of 19±5 μSv/day. Extrapolating the measured spectrum (0.1-1000 MeV), we find that the total neutron-induced dose rate is 6±2 μGy/day and the dose equivalent rate is 30±10 μSv/day. For a 360 day round-trip from Earth to Mars with comparable shielding, this translates into a neutron induced dose equivalent of about 11±4 mSv. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Gene expression of rice seeds surviving 13- and 20-month exposure to space environment.

PubMed

Sugimoto, Manabu; Oono, Youko; Kawahara, Yoshihiro; Gusev, Oleg; Maekawa, Masahiko; Matsumoto, Takashi; Levinskikh, Margarita; Sychev, Vladimir; Novikova, Natalia; Grigoriev, Anatoly

2016-11-01

Rice seeds were exposed outside of the international space station to assess the risk of space environment exposure on gene expression associated with seed germination. The germination percentages of the space-stored and ground-stored seeds exposed for 13 months were 48 and 96% respectively. Those for 20 months were 7 and 76%, respectively. Germination was defined 3 days after imbibition, except for the space-stored seeds exposed for 20 months, which germinated 5 days after imbibition. Subsequent RNA-seq analyses of the dry seeds, germinated seeds, and roots and shoots of seedlings revealed that the mutation rates of mRNA sequences were not significantly different between space-stored and ground-stored samples exposed for 13 months and 20 months. In all, 4 and 16 transcripts of glycolysis-related genes were increased in the germinated seeds after 13-month and 20-month exposure, respectively. Also, 2 and 39 transcripts of long-lived mRNA required for germination were decreased more than 2-fold in the dry seeds after 13-month and 20-month exposure, respectively. These results suggest that damage to long-lived mRNA in seeds by a space environment delays and reduces germination. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

A urine-fuelled soil-based bioregenerative life support system for long-term and long-distance manned space missions.

PubMed

Maggi, Federico; Tang, Fiona H M; Pallud, Céline; Gu, Chuanhui

2018-05-01

A soil-based cropping unit fuelled with human urine for long-term manned space missions was investigated with the aim to analyze whether a closed-loop nutrient cycle from human liquid wastes was achievable. Its ecohydrology and biogeochemistry were analysed in microgravity with the use of an advanced computational tool. Urine from the crew was used to supply primary (N, P, and K) and secondary (S, Ca and Mg) nutrients to wheat and soybean plants in the controlled cropping unit. Breakdown of urine compounds into primary and secondary nutrients as well as byproduct gases, adsorbed, and uptake fractions were tracked over a period of 20 years. Results suggested that human urine could satisfy the demand of at least 3 to 4 out of 6 nutrients with an offset in pH and salinity tolerable by plants. It was therefore inferred that a urine-fuelled life support system can introduce a number of advantages including: (1) recycling of liquids wastes and production of food; (2) forgiveness of neglect as compared to engineered electro-mechanical systems that may fail under unexpected or unplanned conditions; and (3) reduction of supply and waste loads during space missions. Copyright © 2018 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

"Hot" Sodium on Mercury

NASA Astrophysics Data System (ADS)

Potter, A. E.; Morgan, T. H.

1997-07-01

In the course of mapping the sodium emission from Mercury, we found that the sodium exosphere appears to extend to considerable altitudes above the planet (Potter and Morgan, 1997). This suggests that some of the sodium is at a high temperature, but blurring of the data by atmospheric seeing makes it difficult to estimate a temperature from the altitude dependence of the emission. Another way to estimate temperature is to measure the broadening of the emission line caused by thermal motions. We attempted this approach earlier (Potter and Morgan, 1987), but the signal-to-noise in the spectrum was low, and the result was somewhat questionable. We have repeated the measurement,using a modern CCD detector, and obtained a spectrum with excellent signal-to- noise at a spectral resolution of about 600,000. The resulting line profile clearly shows a temperature in excess of a thousand degrees. We are initiating detailed analysis of the line profile, and expect that it will provide new insights into the processes that produce sodium in the exosphere of Mercury. Potter, A.E. and T.H. Morgan, 1987, Variation of sodium on Mercury with solar radiation pressure. Icarus 71, 472-477 Potter, A.E. and T.H. Morgan, 1997, Evidence for suprathermal sodium on Mercury. Presented 31st COSPAR meeting, July 14-21, 1996. To be published, Advances in Space Research.

Cognitive deficits induced by 56Fe radiation exposure

NASA Technical Reports Server (NTRS)

Shukitt-Hale, B.; Casadesus, G.; Cantuti-Castelvetri, I.; Rabin, B. M.; Joseph, J. A.

2003-01-01

Exposing rats to particles of high energy and charge (e.g., 56Fe) disrupts neuronal systems and the behaviors mediated by them; these adverse behavioral and neuronal effects are similar to those seen in aged animals. Because cognition declines with age, and our previous study showed that radiation disrupted Morris water maze spatial learning and memory performance, the present study used an 8-arm radial maze (RAM) to further test the cognitive behavioral consequences of radiation exposure. Control rats or rats exposed to whole-body irradiation with 1.0 Gy of 1 GeV/n high-energy 56Fe particles (delivered at the alternating gradient synchrotron at Brookhaven National Laboratory) were tested nine months following exposure. Radiation adversely affected RAM performance, and the changes seen parallel those of aging. Irradiated animals entered baited arms during the first 4 choices significantly less than did controls, produced their first error sooner, and also tended to make more errors as measured by re-entries into non-baited arms. These results show that irradiation with high-energy particles produces age-like decrements in cognitive behavior that may impair the ability of astronauts to perform critical tasks during long-term space travel beyond the magnetosphere. Published by Elsevier Science Ltd on behalf of COSPAR.

Water Science and Technology Board Annual Report 2001-2002

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

2002-10-01

This annual report marks the twentieth anniversary of the Water Science and Technology Board (WSTB) (1982-2002). The WSTB oversees studies of water issues. The principal products of studies are written reports. These reports cover a wide range of water resources issues of national concern. The following three recently issued reports illustrate the scope of the WSTB's studies: Envisioning the Agenda for Water Resources Research in the Twenty-first Century. The Missouri River Ecosystem: Exploring the Prospects for Recovery, and Assessing the TMDL Approach to Water Quality Management. The WSTB generally meets three times each year where discussions are held on ongoingmore » projects, strategic planning, and developing new initiatives. The meetings also foster communication within the water resources community. The annual report includes a discussion on current studies, completed studies 2001-2002, and future plans, as well as a listing of published reports (1983-2002).« less

International Intelligence Forum 2002

DTIC Science & Technology

2002-01-01

International Intelligence Forum 2002 PCN 46737 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection...Intelligence Forum 2002 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f...Std Z39-18 INTERNATIONAL INTELLIGENCE FORUM -3 The Joint Military Intelligence College created the International Intelligence Fellows Program

Comparison of base flows to selected streamflow statistics representative of 1930-2002 in West Virginia

USGS Publications Warehouse

Wiley, Jeffrey B.

2012-01-01

Base flows were compared with published streamflow statistics to assess climate variability and to determine the published statistics that can be substituted for annual and seasonal base flows of unregulated streams in West Virginia. The comparison study was done by the U.S. Geological Survey, in cooperation with the West Virginia Department of Environmental Protection, Division of Water and Waste Management. The seasons were defined as winter (January 1-March 31), spring (April 1-June 30), summer (July 1-September 30), and fall (October 1-December 31). Differences in mean annual base flows for five record sub-periods (1930-42, 1943-62, 1963-69, 1970-79, and 1980-2002) range from -14.9 to 14.6 percent when compared to the values for the period 1930-2002. Differences between mean seasonal base flows and values for the period 1930-2002 are less variable for winter and spring, -11.2 to 11.0 percent, than for summer and fall, -47.0 to 43.6 percent. Mean summer base flows (July-September) and mean monthly base flows for July, August, September, and October are approximately equal, within 7.4 percentage points of mean annual base flow. The mean of each of annual, spring, summer, fall, and winter base flows are approximately equal to the annual 50-percent (standard error of 10.3 percent), 45-percent (error of 14.6 percent), 75-percent (error of 11.8 percent), 55-percent (error of 11.2 percent), and 35-percent duration flows (error of 11.1 percent), respectively. The mean seasonal base flows for spring, summer, fall, and winter are approximately equal to the spring 50- to 55-percent (standard error of 6.8 percent), summer 45- to 50-percent (error of 6.7 percent), fall 45-percent (error of 15.2 percent), and winter 60-percent duration flows (error of 8.5 percent), respectively. Annual and seasonal base flows representative of the period 1930-2002 at unregulated streamflow-gaging stations and ungaged locations in West Virginia can be estimated using previously published values of statistics and procedures.

Arizona motor vehicle crash facts, 2002

DOT National Transportation Integrated Search

2003-01-01

This publication is a statistical review of the motor vehicle crashes in the State of Arizona for calendar year 2002. The : results are compiled from Arizona Traffic Accident Reports submitted to the Arizona Department of Transportation : by state, c...

National transportation statistics 2003

DOT National Transportation Integrated Search

2004-03-01

Compiled and published by the Bureau of Transportation Statistics (BTS), U.S. : Department of Transportation, National Transportation Statistics 2002 presents : information on the U.S. transportation system1, including its physical components, : safe...

Speckle Interferometry at the Blanco and Soar Telescopes in 2008 and 2009

DTIC Science & Technology

2010-02-01

telescopes has been intermittent, especially in the southern hemisphere (speckle data from the WIYN telescope were published by Horch et al. 1999, 2002...1977a, PASP, 89, 582 Holden, F. 1977b, PASP, 89, 588 Horch , E., Ninkov, Z., van Altena, W. F., Meyer, R. D., Girard, T. M., & Timothy, J. G. 1999...AJ, 117, 548 Horch , E. P., Robinson, S. E., Meyer, R. D., van Altena, W. F., Ninkov, Z., & Piterman, A. 2002, AJ, 123, 3442 Innes, R. T. A. 1905, Ann

Bibliography on the Distribution, Properties, and Uses of Zeolites from Sedimentary Deposits, 1998-2002

USGS Publications Warehouse

Sheppard, Richard A.

2003-01-01

This bibliography is an alphabetical listing by author of about 1,500 publications and formal releases, including patents and selected abstracts, from the world literature on the distribution, properties, and uses of zeolites from sedimentary deposits for the period 1998-2002. The bibliography is available on a 3.5-inch floppy diskette, which was prepared on a MacintoshTM computer using EndNoteTM software. Computer searches of the bibliography can be made by author, year, title, journal, publisher, and keywords.

Remote sensing for oceanography, hydrology and agriculture; Proceedings of Symposia A5, A3 and A9 of the COSPAR 29th Plenary Meeting, Washington, Aug. 28-Sept. 5, 1992

NASA Technical Reports Server (NTRS)

Gower, J. F. R. (Editor); Salomonson, V. V. (Editor); Engman, E. T. (Editor); Ormsby, J. P. (Editor); Gupta, R. K. (Editor)

1993-01-01

New results from satellite studies of the ocean and radar mapping of the earth are presented. Atttention is given to data from the ERS-1 satellite. Synthetic aperture radar mapping of land surface features and sea ice, radar backscatter measurements, and orbit altitude measurements are discussed. The use of remote sensing in hydrology, soil moisture determination, precipitation measurement, agricultural meteorology, and crop growth estimation is reviewed.

Controlled Ecological Life Support Systems: Natural and Artificial Ecosystems

NASA Technical Reports Server (NTRS)

Macelroy, Robert D. (Editor); Thompson, Brad G. (Editor); Tibbitts, Theodore W. (Editor); Volk, Tyler (Editor)

1989-01-01

The scientists supported by the NASA sponsored Controlled Ecological Life Support Systems (CELSS) program have played a major role in creating a Committee on Space Research (COSPAR) section devoted to the development of bioregenerative life support for use in space. The series of 22 papers were sponsored by Subcommission F.4. The papers deal with many of the diverse aspects of life support, and with outgrowth technologies that may have commercial applications in fields such as biotechnology and bioengineering. Papers from researchers in France, Canada, Japan and the USSR are also presented.

Intensive MHD-structures penetration in the middle atmosphere initiated in the ionospheric cusp under quiet geomagnetic conditions

NASA Technical Reports Server (NTRS)

Mateev, L. N.; Nenovski, P. I.; Vellinov, P. I.

1989-01-01

In connection with the recently detected quasiperiodical magnetic disturbances in the ionospheric cusp, the penetration of compressional surface magnetohydrodynamic (MHD) waves through the middle atmosphere is modelled numerically. For the COSPAR International Reference Atmosphere (CIRA) 72 model the respective energy density flux of the disturbances in the middle atmosphere is determined. On the basis of the developed model certain conclusions are reached about the height distribution of the structures (energy losses, currents, etc.) initiated by intensive magnetic cusp disturbances.

SAR Product Improvements and Enhancements - SARprises

DTIC Science & Technology

2013-09-30

paper on current fields at Orkney, Scotland, was accepted for publication in IEEE - TGARS and is currently in press (available on IEEE Xplore as Early...Sea surface velocity vector retrieval using dual-beam interferometry: First demonstration, IEEE TGARS, 43, 2494- 2502, 2005. [2] Chapron, B., F...Bight by airborne along-track interferometric SAR, Proc. IGARSS 2002, 1822-1824, IEEE , 2002. [4] Bjerklie, D.M., S.L. Dingman, C.J. Vorosmarty, C.H

ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - PHYSICAL REMOVAL OF MICROBIOLOGICAL & PARTICULATE CONTAMINANTS IN DRINKING WATER: US FILTER 3M10C MICROFILTRATION MEMBRANE SYSTEM AT CHULA VISTA, CALIFORNIA

EPA Science Inventory

Verification testing of the US Filter 3M10C membrane system was conducted over a 44-day test period at the Aqua 2000 Research Center in Chula Vista, California. The test period extended from July 24, 2002 to September 5, 2002. The source water was a blend of Colorado River and ...

Trends in market share of leading cigarette brands in the USA: national survey on drug use and health 2002-2013.

PubMed

Sharma, Anushree; Fix, Brian V; Delnevo, Cristine; Cummings, K Michael; O'Connor, Richard J

2016-01-29

The main objective of this study is to examine trends in market share for leading cigarette brands, both before (2002-2008) and after (2009-2013) Food and Drug Administration (FDA) regulation of tobacco products.Design Data come from the annual National Survey on Drug Use and Health from 2002 through 2013. Descriptive statistics, cross tabulations, and logistic regression were employed. Data were weighted to the US population and adjusted for cigarette consumption. Our analysis is restricted to 164,343 current cigarette smokers who were at least 12 years of age or older, had smoked at least one cigarette in the 30 days prior to the survey, and reported a usual cigarette brand at the time of the survey. Over 12 years, 14 brands comprised over 77% of the cigarette market. Marlboro consistently held over 38% of the market. Newport held the second highest market share, and increased from 7.2% in 2002 to 10.9% by 2013. Market share of Pall Mall grew by over 400% (1.7% in 2002 vs 8.9% in 2013), likely aided by the 2009 Federal excise tax increase. No clear associations of changes in market share with the implementation of FDA's regulatory authority over tobacco in 2009 were noted. Tracking market share trends offers clues about brand marketing changing preferences of consumers. Rapidly growing cigarette brands should be monitored to determine if specific marketing practices or design changes are drivers, as these could represent public health concerns. Monitoring trends in cigarette market share could inform regulatory decision-making efforts related to marketing and advertising. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Community Report and Recommendations from International Lunar Exploration Working Group (ILEWG)

NASA Astrophysics Data System (ADS)

Foing, Bernard H.

2016-07-01

The International Lunar Exploration Working Group (ILEWG) was established in April 1995 at a meeting in Hamburg, Germany. As established in its charter, this working group reports to COSPAR and is charged with developing an international strategy for the exploration of the Moon. It discusses coordination between missions, and a road map for future international lunar exploration and utilisation. It fosters information exchange or potential and real future lunar robotic and human missions, as well as for new scientific and exploration information about the Moon. We refer to COSPAR and ILEWG ICEUM and lunar conferences and declarations [1-18], present the GLUC/ICEUM11 declaration and give a report on ongoing relevant ILEWG community activities. ILEWG supported community forums, ILEWG EuroMoonMars field campaigns and technology validation activities, as well as Young Lunar Explorers events, and activities with broad stakeholders. We discuss how lunar missions SMART-1, Kaguya, Chang'E1&2, Chandrayaan-1, LCROSS, LRO, GRAIL, LADEE, Chang'E3 and upcoming missions contribute to lunar exploration objectives & roadmap towards the Moon Village. GLUC/ICEUM11 declaration: "467 International Lunar Explorers, registered delegates from 26 countries, assembled at GLUC Global Lunar Conference including the 11th ILEWG Conference on Exploration and Utilisation of the Moon (ICEUM11) in Beijing. The conference engaged scientists, engineers, enthusiast explorers, agencies and organisations in the discussion of recent results and activities and the review of plans for exploration. Space agencies representatives gave the latest reports on their current lunar activities and programmes. GLUC-ICEUM11 was a truly historical meeting that demonstrated the world-wide interest in lunar exploration, discovery, and science. More than 400 abstracts were accepted for oral and poster presentations in the technical sessions, organised in 32 sessions within 4 symposia: Science and Exploration; Technology and Resource Utilisation; Infrastructure and Human aspects; Moon, Space and Society. The latest technical achievements and results of recent missions (SMART-1, Kaguya, Chang'E1, Chandrayaan-1, LCROSS and LRO) were discussed at a plenary panel and technical sessions, with the Lunar Reconnaissance Orbiter (LRO) still in operation. Chang'E1 has generated many useful results for the community. Four plenary panel sessions were conducted: 1. What are the plans? 2. New mission results; 3. From space stations and robotic precursors to lunar bases; 4. Moon, Space, Society The participants summarised their findings, discussions and recommend o continue efforts by agencies and the community on previous ICEUM recommendations, and the continuation of the ILEWG forum, technical groups activities and pilot projects. 1. Science and exploration - World-wide access to raw and derived (geophysical units) data products using consistent formats and coordinate systems will maximize return on investment. We call to develop and implement plans for generation, validation, and release of these data products. Data should be made available for scientific analysis and supporting the development and planning of future missions - There are still Outstanding Questions: Structure and composition of crust, mantle, and core and implications for the origin and evolution of the Earth-Moon system; Timing, origin, and consequences of late heavy bombardment; Impact processes and regolith evolution; Nature and origin of volatile emplacement; Implications for resource utilization. These questions require international cooperation and sharing of results in order to be answered in a cost-effective manner - Ground truth information on the lunar far side is missing and needed to address many important scientific questions, e.g. with a sample return from South Pole- Aitken Basin - Knowledge of the interior is poor relative to the surface, and is needed to address a number of key questions, e.g. with International Lunar Network for seismometry and other geophysical measurements - Lunar missions will be driven by exploration, resource utilization, and science; we should consider minimum science payload for every mission, e.g., landers and rovers should carry instruments to determine surface composition and mineralogy - It is felt important to have a shared database about previous missions available for free, so as to provide inputs to future missions, including a gap analysis of needed measurements. Highly resolved global data sets are required. Autonomous landing and hazard avoidance will depend on the best topographic map of the Moon, achievable by combining shared data. - New topics such as life sciences, partial gravity processes on the Moon should be followed in relation to future exploration needs. 2. Technologies and resources - A number of robotic missions to the Moon are now undertaken independently by various nations, with a degree of exchange of information and coordination. That should increase towards real cooperation, still allowing areas of competition for keeping the process active, cost-effective and faster. - Lunar landers, pressurized lunar rover projects as presented from Europe, Asia and America are important steps that can create opportunities for international collaboration, within a coordinated village of robotic precursors and assistants to crew missions. - We have to think about development, modernization of existing navigation capabilities, and provision of lunar positioning, navigation and data relay assets to support future robotic and human exploration. New concepts and new methods for transportation have attracted much attention and are of great potential. 3. Infrastructures and human aspects - It is recommended to have technical sessions and activities dealing with different aspects of human adaptation to space environments, the modeling of sub-systems, microbial protection and use of inflatable technologies - While the Moon is the best and next logical step in human exploration, we should make best use of the space stations as stepping stones for exploration and human spaceflight beyond Low Earth Orbit. - Further research is needed on lunar dust aspects in regard to humans and interaction with habitats. We note high interest in CELSS for Moon and Mars bases, and recommend further research and development. - We recommend the development and use of terrestrial analogues research sites and facilities, for technology demonstrations, comparative geology and human performance research, and public engagement. We endorse the proposal of development of a site at La Reunion for international Moon-Mars analogue research. 4. Moon, Space, Society and Young Explorers - We consider that the current legal regime as set out in the Outer Space Treaty and the Moon agreement are satisfactory for current and future missions, but may require further clarification for future exploration. Issues of transparency and security will need to be addressed. - Great things are happening for Young Lunar Explorers, with inspiring missions and hands-on activities as coordinated by ILEWG. Lunar exploration is encouraging students of all ages to pursue higher education. - More possibilities for participatory engagement should be offered to the society for example via interdisciplinary activities with the humanities. - We appreciate the work from COSPAR panel on Exploration PEX that should be shared further. - Continued cooperation should be enforced at all levels. The space community feels strongly that joining the forces of space faring nations to explore the Moon should be seriously implemented, with the views of expanding a Global Robotic Village and building in the long run a Manned International Lunar Base. - We propose that a panel be formed through ILEWG with the help of IAF and Chinese Society of Astronautics in cooperation with space agencies, COSPAR and other stakeholders in order to initiate a permanent International Space Exploration Governance Forum We, the participants of the GLUC-ICEUM11 conference, commit to an enhanced global cooperation towards international lunar exploration for the benefit of humankind. Endorsed by the delegates of GLUC-ICEUM11" References: [1] 1st International Lunar Workshop, Balsiger H. et al., Editors, European Space Agency, 1994. ESA-SP-1170. [2] 2nd International Lunar Workshop, Kyoto, H. Mizutani, editor, Japan Space Forum Publisher, 1997. [3] 3rd International Lunar Workshop, Moscow 1998, E. Galimov, editor. [4] ICEUM4, ESTEC, 2000, ESA SP-462, B.H. Foing & M. Perry, editors. [5] ICEUM5, Hawaii Nov 2003, Durst S.M. et al, Editors, Vol 108, 1-576 pp, Science and Technology Series, American Astronautical Society, 2004. [6] ICEUM6, Udaipur 2004, Bhandari N., Editor, Journal Earth System Science, India, 114, No6, Dec 2005, pp. 573-841. [7] ICEUM7, Toronto Sept 2005, sci.esa.int/ilewg. [8] ICEUM8, Beijing July 2006, Journal of Chinese Society of Astronautics, Vol. 28 Sup., 2007, Ji W., Editor. [9] ICEUM9, Sorrento, Italy, Foing B., Espinasse S., Kosters G., Editors. http://sci.esa.int/iceum9, Dec. 2007), [11] Ehrenfreund, P., Foing, B.H., Cellino, A. Editors, The Moon and Near Earth Objects, ASR Vol 37, 1, 2006. [12] Foing, B.H. et al editors, 'Astronomy and Space Science from the Moon', ASR 14, 6, 1994. [13] Ip W.-H., Foing, B.H., Masson Ph.L., editors, The Moon and Mars, ASR Vol 23, 11, 1999. [14] Foing, B.H. et al, editor, Lunar Exploration, Planetary and Space Science, Vol 50, 14-15, 2002. [15] Foing, B.H., Heather, D. editors, 'Lunar Exploration 2000', ASR Vol 30, Nr 8, 2002. [16] Huntress, W. et al 'The next steps in exploring deep space - A cosmic study by the IAA', Acta Astronautica, Vol 58, Issues 6-7, 2006, p302-377. [17] http://sci.esa.int/ilewg/43654-declaration-iceum10-leag-srr-florida-2008/ [18] Ehrenfreund P. et al (COSPAR planetary exploration panel report) 2012, ASR Vol 49, Nr 1, pp. 2-48.

Effects of mass transfer between Martian satellites on surface geology

DTIC Science & Technology

2015-12-21

University Affiliated Research Center (UARC). Thanks to Bill Folkner (JPL/Caltech) for high-fidelity long-term Phobos/Deimos SPICE orbit propagations, and...created by JPL/Caltech to SPICE ephemeris information from NASA’s Navigation and Ancillary Information Facility (naif.jpl.nasa.gov) (Acton et al., 2002...References Acton, C. et al., 2002. Extending NASA’s SPICE ancillary information system to meet future mission needs. In: 2002 AIAA Space Operations

Homeland Security, A Primary Army Function

DTIC Science & Technology

2002-01-01

www.efilmqroup.com/nowhere.html>; Internet; accessed 27 January 2002 . ൕ Ibid., 1-4. 14 Gannon , John C., "The US Intelligence Community and Biological...Release. Distribution is Unlimited. USAWC CLASS OF 2002 U.S. ARMY WAR COLLEGE, CARLISLE BARRACKS, PA 17013-5050 20020502 072 USAWC STRATEGY RESEARCH PROJECT...Project DATE: 09 April 2002 PAGES:43 CLASSIFICATION: Unclassified This paper will explore new Army requirements based on the September 2001 Quadrennial

"Good Books": Is There a Future for Academic Writing within the Educational Publishing Industry?

ERIC Educational Resources Information Center

Nixon, Jon; Wellington, Jerry

2005-01-01

This paper draws on questionnaire responses received (via e-mail) during the period 2002-2003 from senior commissioning editors located within seven of the major UK publishing outlets. Drawing on the analytical framework of an earlier study by Nixon (1999), it focuses on the mediation of educational studies by market forces operating within and…

Fifteen Years of Publication: "Leadership and Policy in Schools" and Its Scholarly Contribution since Its Foundation

ERIC Educational Resources Information Center

Oplatka, Izhar

2017-01-01

The purpose of the current article is to reflect systematically on articles published in Leadership and Policy in Schools (LPS) since its foundation in 2002 to the present time (2016). Based on qualitative content analysis of the journal's articles, it was found that "LPS" has published articles about clear and demarcated areas of study,…

The Face of Society: Gender and Race in Introductory Sociology Books Revisited

ERIC Educational Resources Information Center

Clark, Roger; Nunes, Alex

2008-01-01

We have updated Ferree and Hall's (1990) study of the way gender and race are constructed through pictures in introductory sociology textbooks. Ferree and Hall looked at 33 textbooks published between 1982 and 1988. We replicated their study by examining 3,085 illustrations in a sample of 27 textbooks, most of which were published between 2002 and…

Growth of pea epicotyl in low magnetic field: implication for space research.

PubMed

Negishi, Y; Hashimoto, A; Tsushima, M; Dobrota, C; Yamashita, M; Nakamura, T

1999-01-01

A magnetic field is an inescapable environmental factor for plants on the earth. However, its impact on plant growth is not well understood. In order to survey how magnetic fields affect plant, Alaska pea seedlings were incubated under low magnetic field (LMF) and also in the normal geo-magnetic environment. Two-day-old etiolated seedlings were incubated in a magnetic shield box and in a control box. Sedimentation of amyloplasts was examined in the epicotyls of seedlings grown under these two conditions. The elongation of epicotyls was promoted by LMF. Elongation was most prominent in the middle part of the epicotyls. Cell elongation and increased osmotic pressure of cell sap were found in the epidermal cells exposed to LMF. When the gravitational environment was 1G, the epicotyls incubated under both LMF and normal geomagnetic field grew straight upward and amyloplasts sedimented similarly. However, under simulated microgravity (clinostat), epicotyl and cell elongation was promoted. Furthermore, the epicotyls bent and amyloplasts were dispersed in the cells in simulated microgravity. The dispersion of amyloplasts may relate to the posture control in epicotyl growth under simulated microgravity generated by 3D clinorotation, since it was not observed under LMF in 1G. Since enhanced elongation of cells was commonly seen both at LMF and in simulated microgravity, all elongation on the 3D-clinostat could result from pseudo-low magnetic field, as a by-product of clinorotation. (i.e., clinostat results could be based on randomization of magnetic field together with randomization of gravity vector.) Our results point to the possible use of space for studies in magnetic biology. With space experiments, the effects of dominant environmental factors, such as gravity on plants, could be neutralized or controlled for to reveal magnetic effects more clearly. c1999 COSPAR. Published by Elsevier Science Ltd.

The promotive effect of latrunculin B on maize root gravitropism is concentration dependent

NASA Technical Reports Server (NTRS)

Blancaflor, E. B.; Hou, G-C; Mohamalawari, D. R.

2003-01-01

The cytoskeleton has been proposed to be a key player in the gravitropic response of higher plants. A major approach to determine the role of the cytoskeleton in gravitropism has been to use inhibitors to disrupt the cytoskeleton and then to observe the effect that such disruption has on organ bending. Several investigators have reported that actin or microtubule inhibitors do not prevent root gravitropism, leading to the conclusion that the cytoskeleton is not involved in this process. However, there are recent reports showing that disruption of the actin cytoskeleton with the actin inhibitor, latrunculin B, promotes the gravitropic response of both roots and shoots. In roots, curvature is sustained during prolonged periods of clinorotation despite short periods of gravistimulation. These results indicate that an early gravity-induced signal continues to persist despite withdrawal of the constant gravity stimulus. To investigate further the mechanisms underlying the promotive effect of actin disruption on root gravitropism, we treated maize roots with varying concentrations of latrunculin B in order to determine the lowest concentration of latrunculin B that has an effect on root bending. After a 10-minute gravistimulus, treated roots were axially rotated on a one rpm clinostat and curvature was measured after 15 hours. Our results show that 100 nM latrunculin B induced the strongest promotive effect on the curvature of maize roots grown on a clinostat. Moreover, continuously gravistimulated roots treated with 100 nM latrunculin B exhibited stronger curvature responses while decapped roots treated with this concentration of latrunculin B did not bend during continuous gravistimulation. The stronger promotive effect of low concentrations of latrunculin B on the curvature of both clinorotated and continuously gravistimulated roots suggests that disruption of the finer, more dynamic component of the actin cytoskeleton could be the cause of the enhanced tropic responses of roots to gravity. c2003 COSPAR. Published by Elsevier Ltd. All rights reserved.

"Living off the land": resource efficiency of wetland wastewater treatment.

PubMed

Nelson, M; Odum, H T; Brown, M T; Alling, A

2001-01-01

Bioregenerative life support technologies for space application are advantageous if they can be constructed using locally available materials, and rely on renewable energy resources, lessening the need for launch and resupply of materials. These same characteristics are desirable in the global Earth environment because such technologies are more affordable by developing countries, and are more sustainable long-term since they utilize less non-renewable, imported resources. Subsurface flow wetlands (wastewater gardens(TM)) were developed and evaluated for wastewater recycling along the coast of Yucatan. Emergy evaluations, a measure of the environmental and human economic resource utilization, showed that compared to conventional sewage treatment, wetland wastewater treatment systems use far less imported and purchased materials. Wetland systems are also less energy-dependent, lessening dependence on electrical infrastructure, and require simpler maintenance since the system largely relies on the ecological action of microbes and plants for their efficacy. Detailed emergy evaluations showed that wetland systems use only about 15% the purchased emergy of conventional sewage systems, and that renewable resources contribute 60% of total emergy used (excluding the sewage itself) compared to less than 1% use of renewable resources in the high-tech systems. Applied on a larger scale for development in third world countries, wetland systems would require the electrical energy of conventional sewage treatment (package plants), and save of total capital and operating expenses over a 20-year timeframe. In addition, there are numerous secondary benefits from wetland systems including fiber/fodder/food from the wetland plants, creation of ecosystems of high biodiversity with animal habitat value, and aesthestic/landscape enhancement of the community. Wetland wastewater treatment is an exemplar of ecological engineering in that it creates an interface ecosystem to handle byproducts of the human economy, maximizing performance of the both the natural economy and natural ecosystems. Wetland systems accomplish this with far greater resource economy than other sewage treatment approaches, and thus offer benefits for both space and Earth applications. c 2001. COSPAR. Published by Elsevier Science Ltd. All rights reserved.

A priming dose of protons alters the early cardiac cellular and molecular response to (56)Fe irradiation.

PubMed

Ramadan, Samy S; Sridharan, Vijayalakshmi; Koturbash, Igor; Miousse, Isabelle R; Hauer-Jensen, Martin; Nelson, Gregory A; Boerma, Marjan

2016-02-01

Recent evidence suggests that the heart may be injured by ionizing radiation at lower doses than was previously thought. This raises concerns about the cardiovascular risks from exposure to radiation during space travel. Since space travel is associated with exposure to both protons from solar particle events and heavy ions from galactic cosmic rays, we here examined the effects of a "priming" dose of protons on the cardiac cellular and molecular response to a "challenge" dose of (56)Fe in a mouse model. Male C57BL/6 mice at 10 weeks of age were exposed to sham-irradiation, 0.1 Gy of protons (150 MeV), 0.5 Gy of (56)Fe (600 MeV/n), or 0.1 Gy of protons 24 hours prior to 0.5 Gy of (56)Fe. Hearts were obtained at 7 days post-irradiation and western-blots were used to determine protein markers of cardiac remodeling, inflammatory infiltration, and cell death. Exposure to (56)Fe caused an increase in expression of α-smooth muscle cell actin, collagen type III, the inflammatory cell markers mast cell tryptase, CD2 and CD68, the endothelial glycoprotein thrombomodulin, and cleaved caspase 3. Of all proteins investigated, protons at a dose of 0.1 Gy induced a small increase only in cleaved caspase 3 levels. On the other hand, exposure to protons 24 hours before (56)Fe prevented all of the responses to (56)Fe. This study shows that a low dose of protons may prime the heart to respond differently to a subsequent challenge dose of heavy ions. Further investigation is required to identify responses at additional time points, consequences for cardiac function, threshold dose levels, and mechanisms by which a proton priming dose may alter the response to heavy ions. Copyright © 2015 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

The biological component of the life support system for a Martian expedition.

PubMed

Sychev, V N; Levinskikh, M A; Shepelev, Ye Ya

2003-01-01

Ground-based experiments at RF SSC-IBMP RAS (State Science Center of Russian Federation--Institute of Biomedical Problems of Russian Academia of Science) were aimed at overall studies of a human-unicellular algae-mineralization LSS (life support system) model. The system was 15 m3 in volume. It contained 45 L of algal suspension with a dry substance density of 10-12 g per liter; water volume, including the algal suspension, was 59 L. More sophisticated model systems with partial substitution of unicellular algae with higher plates (crop area of 15 m2) were tested in three experiments from 1.5 to 2 months in duration. The experiments demonstrated that LSS employing the unicellular algae play not only a macrofunction (regeneration of atmosphere and water) but also carry some other functions (purification of atmosphere, formation of microbial cenosis etc.) providing an adequate human environment. It is also important that functional reliability of the algal regenerative subsystem is secured by a huge number of cells able, in the event of death of a part of population, to recover in the shortest possible time the size of population and, hence, functionality of the LSS autotrophic component. For a long period of time a Martian crew will be detached from Earth's biosphere and for this reason LSS of their vehicle must be highly reliable, robust and redundant. One of the approaches to LSS redundancy is installation of two systems with different but equally efficient regeneration technologies, i.e. physical-chemical and biological. At best, these two systems should operate in parallel sharing the function of regeneration of the human environment. In case of failure or a sharp deterioration in performance of one system the other will, by way of redundancy, increase its throughput to make up for the loss. This LSS design will enable simultaneous handling of a number of critical problems including adequate satisfaction of human environmental needs. c2003 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

The actual development of European Aviation Safety Requirements in Aviation Medicine: Prospects of Future EASA Requirements

PubMed Central

Siedenburg, J

2009-01-01

Common Rules for Aviation Safety had been developed under the aegis of the Joint Aviation Authorities in the 1990ies. In 2002 the Basic Regulation 1592/2002 was the founding document of a new entity, the European Aviation Safety Agency. Areas of activity were Certification and Maintenance of aircraft. On 18 March the new Basic Regulation 216/2008, repealing the original Basic Regulation was published and applicable from 08 April on. The included Essential Requirements extended the competencies of EASA inter alia to Pilot Licensing and Flight Operations. The future aeromedical requirements will be included as Annex II in another Implementing Regulation on Personnel Licensing. The detailed provisions will be published as guidance material. The proposals for these provisions have been published on 05 June 2008 as NPA 2008- 17c. After public consultation, processing of comments and final adoption the new proposals may be applicable form the second half of 2009 on. A transition period of four year will apply. Whereas the provisions are based on Joint Awiation Requirement - Flight Crew Licensing (JAR-FCL) 3, a new Light Aircraft Pilot Licence (LAPL) project and the details of the associated medical certification regarding general practitioners will be something new in aviation medicine. This paper consists of 6 sections. The introduction outlines the idea of international aviation safety. The second section describes the development of the Joint Aviation Authorities (JAA), the first step to common rules for aviation safety in Europe. The third section encompasses a major change as next step: the foundation of the European Aviation Safety Agency (EASA) and the development of its rules. In the following section provides an outline of the new medical requirements. Section five emphasizes the new concept of a Leisure Pilot Licence. The last section gives an outlook on ongoing rulemaking activities and the opportunities of the public to participate in them. PMID:19561781

The actual development of European aviation safety requirements in aviation medicine: prospects of future EASA requirements.

PubMed

Siedenburg, J

2009-04-01

Common Rules for Aviation Safety had been developed under the aegis of the Joint Aviation Authorities in the 1990s. In 2002 the Basic Regulation 1592/2002 was the founding document of a new entity, the European Aviation Safety Agency. Areas of activity were Certification and Maintenance of aircraft. On 18 March the new Basic Regulation 216/2008, repealing the original Basic Regulation was published and applicable from 08 April on. The included Essential Requirements extended the competencies of EASA inter alia to Pilot Licensing and Flight Operations. The future aeromedical requirements will be included as Annex II in another Implementing Regulation on Personnel Licensing. The detailed provisions will be published as guidance material. The proposals for these provisions have been published on 05 June 2008 as NPA 2008- 17c. After public consultation, processing of comments and final adoption the new proposals may be applicable form the second half of 2009 on. A transition period of four year will apply. Whereas the provisions are based on Joint Aviation Requirement-Flight Crew Licensing (JAR-FCL) 3, a new Light Aircraft Pilot Licence (LAPL) project and the details of the associated medical certification regarding general practitioners will be something new in aviation medicine. This paper consists of 6 sections. The introduction outlines the idea of international aviation safety. The second section describes the development of the Joint Aviation Authorities (JAA), the first step to common rules for aviation safety in Europe. The third section encompasses a major change as next step: the foundation of the European Aviation Safety Agency (EASA) and the development of its rules. In the following section provides an outline of the new medical requirements. Section five emphasizes the new concept of a Leisure Pilot Licence. The last section gives an outlook on ongoing rulemaking activities and the opportunities of the public to participate in them.

Pharmaceutical company sponsored disease management programs: an alternative for tax-exempt MCOs and hospitals.

PubMed

Jedrey, Christopher M; Chaurette, Katherine A; Winn, Lara Beth

2002-01-01

On April 25, 2002, the Internal Revenue Service finalized the proposed Corporate Sponsorship regulations. The changes made in the final regulations pertain to the proposed $79 ceiling on disregarded benefits, the 2 percent threshold for disregarded benefits, the scope of disregarded benefits, Web site hyperlinks, the inclusion of certain electronic publications in the definition of periodicals, the valuation date for substantial return benefits, and the scope of use or acknowledgement. The proposed regulations were discussed in the Winter 2002 issue of Managed Care Quarterly in an article titled the same as this one. This article is based on the final IRS regulations and therefore supersedes the original article published in the Winter 2002 issue.

Caspase-8 Deficiency Presenting as Late-Onset Multi-Organ Lymphocytic Infiltration with Granulomas in two Adult Siblings.

PubMed

Niemela, Julie; Kuehn, Hye Sun; Kelly, Corin; Zhang, Mingchang; Davies, Joie; Melendez, Jose; Dreiling, Jennifer; Kleiner, David; Calvo, Katherine; Oliveira, João B; Rosenzweig, Sergio D

2015-05-01

Caspase-8 deficiency (CED) was originally described in 2002 in two pediatric patients presenting with clinical manifestations resembling autoimmune lymphoproliferative syndrome (ALPS) accompanied by infections, and T, B and NK cell defects. Since then, no new CED patients were published. Here we report two adult siblings (Pt1 and Pt2) presenting in their late thirties with pulmonary hypertension leading to lung transplant (Pt1), and a complex neurological disease leading to multiple cranial nerves palsies (Pt2) as their main manifestations. A thorough clinical and immunological evaluation was performed at the Primary Immunodeficiency Clinic at NIH, followed by whole exome sequencing. The patients had multiorgan lymphocytic infiltration and granulomas, as well as clinical signs of immune deficiency/ immune dysregulation. Both siblings carried homozygous mutations in CASP8, c.1096C > T, p.248R > W. This was the same mutation described on the previously published CED patients, to whom these new patients were likely distantly related. We report two new CED patients presenting during adulthood with life-threatening end-organ lymphocyte infiltrates affecting the lungs, liver, spleen, bone marrow and central nervous system. This phenotype broadens the clinical spectrum of manifestations associated with this disease and warrants the search of CASP8 mutations in other cohorts of patients.

47 CFR 1.2002 - Applicants required to submit information.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Grants by Random Selection Implementation of the Anti-Drug Abuse Act of 1988 § 1.2002 Applicants required... benefits that includes FCC benefits pursuant to section 5301 of the Anti-Drug Abuse Act of 1988. 21 U.S.C...

47 CFR 1.2002 - Applicants required to submit information.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Grants by Random Selection Implementation of the Anti-Drug Abuse Act of 1988 § 1.2002 Applicants required... benefits that includes FCC benefits pursuant to section 5301 of the Anti-Drug Abuse Act of 1988. 21 U.S.C...

47 CFR 1.2002 - Applicants required to submit information.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Grants by Random Selection Implementation of the Anti-Drug Abuse Act of 1988 § 1.2002 Applicants required... benefits that includes FCC benefits pursuant to section 5301 of the Anti-Drug Abuse Act of 1988. 21 U.S.C...

Concepts & Procedures. [SITE 2002 Section].

ERIC Educational Resources Information Center

Sarner, Ronald, Ed.; Mullick, Rosemary J., Ed.; Bauder, Deborah Y., Ed.

This document contains the following full and short papers on concepts and procedures from the SITE (Society for Information Technology & Teacher Education) 2002 conference: "Exploring Minds Network" (Marino C. Alvarez and others); "Learning Communities: A Kaleidoscope of Ecological Designs" (Alain Breuleux and others);…

Outstanding Science Trade Books for Students K-12.

ERIC Educational Resources Information Center

Science Teacher, 2003

2003-01-01

Presents outstanding science trade books published in 2002 for students in grades K-12. Sections include Archaeology, Anthropology, and Paleontology; Biography; Environment and Ecology; Life Science; Physical Science; and Science-Related Careers. (KHR)

The increasing internationalization of mainstream posttraumatic stress disorder research: a bibliometric study.

PubMed

Figueira, Ivan; da Luz, Mariana; Braga, Raphael J; Cabizuca, Mariana; Coutinho, Evandro; Mendlowicz, Mauro V

2007-02-01

The aim of this study was to quantify changes in the national contributions to research related to posttraumatic stress disorder (PTSD) from 1983 through 2002. Using the Web of Science database (Thomson Scientific, Philadelphia, PA), we classified articles according to the year of publication and the country of the authors. The number of publishing countries increased from 7 between 1983 and 1987 to 39 between 1998 and 2002. Meanwhile, the U.S. output share declined from 87.6% in the first period to 62.4%. Although the number of countries publishing on PTSD has steadily increased, research is still dominated qualitatively and quantitatively by developed countries. These findings suggest a growing international acceptance of this diagnostic category. However, the immaturity of PTSD research is demonstrated by the concentration of publications in a few countries.

Nonablative laser resurfacing: state of the art 2002.

PubMed

Pozner, Jason N; Goldberg, David J

2002-09-01

The reader is presumed to have a basic understanding of the use of lasers in plastic surgery and laser physics. After reading this article, the participant should be able to: Physicians may earn 1 hour of Category 1 CME credit by successfully completing the examination on the basis of material covered in this article. The examination begins on page 435. Nonablative resurfacing, also referred to as subsurface or dermal remodeling, is a recently introduced technology for restoring damaged collagen without injuring or removing the overlying epidermis. To date there have been no published comparisons or reviews of these laser systems. The authors review the mechanisms of action of currently available nonablative laser technologies and published data on their performance. Literature concerning nonablative laser technology published between 2000 and 2002 was reviewed by use of Medline searches. Data on technical specifications were obtained from the manufacturers. Significant improvement in skin elasticity and photodamage with few or no complications was noted after treatment with most of the systems reviewed. However, the results were generally more subtle than those achieved with ablative lasers. Nonablative technology is currently at the forefront of skin rejuvenation. Data on long-term results must await several more years of accumulated clinical treatment. Improvement in skin quality, tone, and texture can be expected, but patients and physicians who expect nonablative laser treatment results to be similar to those achieved by ablative techniques may be disappointed. (Aesthetic Surg J 2002;22:427-434.).

Impact of using different blood donor subpopulations and models on the estimation of transfusion transmission residual risk of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus in Zimbabwe.

PubMed

Mapako, Tonderai; Janssen, Mart P; Mvere, David A; Emmanuel, Jean C; Rusakaniko, Simbarashe; Postma, Maarten J; van Hulst, Marinus

2016-06-01

Various models for estimating the residual risk (RR) of transmission of infections by blood transfusion have been published mainly based on data from high-income countries. However, to obtain the data required for such an assessment remains challenging for most developing settings. The National Blood Service Zimbabwe (NBSZ) adapted a published incidence-window period (IWP) model, which has less demanding data requirements. In this study we assess the impact of various definitions of blood donor subpopulations and models on RR estimates. We compared the outcomes of two published models and an adapted NBSZ model. The Schreiber IWP model (Model 1), an amended version (Model 2), and an adapted NBSZ model (Model 3) were applied. Variably the three models include prevalence, incidence, preseroconversion intervals, mean lifetime risk, and person-years at risk. Annual mean RR estimates and 95% confidence intervals for each of the three models for human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) were determined using NBSZ blood donor data from 2002 through 2011. The annual mean RR estimates for Models 1 through 3 were 1 in 6542, 5805, and 6418, respectively for HIV; 1 in 1978, 2027, and 1628 for HBV; and 1 in 9588, 15,126, and 7750, for HCV. The adapted NBSZ model provided comparable results to the published methods and these highlight the high occurrence of HBV in Zimbabwe. The adapted NBSZ model could be used as an alternative to estimate RRs when in settings where two repeat donations are not available. © 2016 AABB.

[Effects of eutrophication on distribution and population density of Corbicula fluminea and Bellamya sp. in Chaohu Lake].

PubMed

Deng, Daogui; Li, Hongyuan; Hu, Wanming; Zhou, Qiong; Guo, Longgen

2005-08-01

The investigation on the distribution an d population density of C. fluminea and Bellamya sp. in Chaohu Lake during September 2001 and September 2002 showed that in the west region of the lake where was seriously eutrophic, the density and biomass of C. fluminea were 5.1 ind. x m(-2) and 17.87 g x m(-2) in 2001, and 8.8 ind. x m(-2) and 47.29 g x m(-2) in 2002, while those of Bellamya sp. were 13.3 ind. x m(-2) and 45.45 g x m(-2) in 2001, and 3.8 ind. x m(-2) and 12.56 g x m(-2) in 2002, respectively. In the east region of the lake where was eutrophic, the density and biomass of C. fluminea were 23.8 ind. x m(-2) and 67.86 g x m(-2) in 2001, and 29.2 ind. x m(-2) and 96.18 g x m(-2) in 2002, while those of Bellamya sp. were 10.1 ind. x m(-2) and 32.00 g x m(-2) in 2001, and 9.4 ind. x m(-2) and 31.21 g x m(-2) in 2002, respectively. The density and biomass of C. fluminea and Bellamya sp. were declined with increasing eutrophication. In hypertrophic region, C. fluminea and Bellamya sp. were absent. The density and biomass of the two species were obviously higher in littoral than in pelagic region. The distribution type of C. fluminea was core-model, while that of Bellamya sp. was random. The correlation between the density and biomass of C. fluminea and Bellamya sp. and water depth was not significant (P > 0.05). The biomass of Bellamya sp. was negatively correlated with water TN (P < 0.01), NO3-N (P < 0.05), TP(P < 0.01) and PO4-P (P < 0.05), while that of C. fluminea only had a significantly negative correlation with PO4-P(P < 0.05). Compared with 1981, there was fewer C. fluminea in the lake nowadays. The effects of other environmental factors on the population distribution and growth of C. fluminea and Bellamya sp. were also discussed.

Julius Caesar and the Gallic Campaign: A Roadmap to the Use of the Instruments of Power

DTIC Science & Technology

2010-03-30

David R Godine Publishing Inc, 1980), 10-13, 17. 13 Kate Gilliver, Caesar’s Gallic Wars, (Oxford: Osprey Publishing, 2002), 74. 14 Plutarch , Fall of...information, see Goldsworthy, Caesar: A Life of a Colossus, 316. 88 Plutarch , 269. 89 Lord Kitchener was the British general credited with winning the...Serverin and Siedler; London: HarperCollins, 1995. Penrose, Jane, ed., Rome and Her Enemies. Oxford, UK: Osprey Publishing Ltd, 2008. Plutarch , Fall of

47 CFR 1.2002 - Applicants required to submit information.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Implementation of the Anti-Drug Abuse Act of 1988 § 1.2002 Applicants required to submit information. (a) In... benefits pursuant to section 5301 of the Anti-Drug Abuse Act of 1988. 21 U.S.C. 862. If a section 5301...

47 CFR 1.2002 - Applicants required to submit information.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Implementation of the Anti-Drug Abuse Act of 1988 § 1.2002 Applicants required to submit information. (a) In... benefits pursuant to section 5301 of the Anti-Drug Abuse Act of 1988. 21 U.S.C. 862. If a section 5301...

Ethical Considerations and Planetary Protection for Future Space Exploration - Starting with the Basics

NASA Astrophysics Data System (ADS)

Race, Margaret

2012-07-01

As COSPAR scientists deliberate what types of frameworks and policy approaches may be applicable to future activities by various sectors in space exploration, it also needs to consider the challenging question of what ethical values and foundations should be used in dealing with life, objects and activities in outer space. A 2010 COSPAR Workshop Report on Ethical Considerations for Planetary Protection in Space Exploration recommended that it is appropriate to maintain the existing PP policy aimed at scientific concerns even as we begin to explore various practical approaches to future contamination avoidance policies. It is also appropriate to examine in parallel the ethical considerations applicable to potential indigenous extraterrestrial life, non-living extraterrestrial features and environments, and planned uses and activities involving diverse life from Earth. Since numerous sectors have begun to propose activities raising varied ethical concerns (e.g., protection and management on the moon, strip mining, space synthetic biology, space code of conduct, and commercial space transport), it is timely to initiate serious international discussions about the appropriate ethical foundations and questions applicable to future space exploration. Plans are underway for convening interdisciplinary work groups to explore and deliberate on the values (e.g., intrinsic and instrumental) and ethical foundations that are appropriate for use in deliberations involving potential indigenous extraterrestrial life and the different classes of target objects and environments in our solar system. More than ever, information on bioethics, environmental ethics and geoethics will provide helpful guidance and foundational approaches of relevance to future policy deliberations that seek to go beyond science protection per se.

The International Reference Ionosphere Today and in the Future

NASA Technical Reports Server (NTRS)

Bilitza, Dieter; McKinnell, Lee-Ane; Reinisch, Bodo; Fuller-Rowell,Tim

2010-01-01

The international reference ionosphere (IRI) is the internationally recognized and recommended standard for the specification of plasma parameters in Earth's ionosphere. It describes monthly averages of electron density, electron temperature, ion temperature, ion composition, and several additional parameters in the altitude range from 60 to 1,500 km. A joint working group of the Committee on Space Research (COSPAR) and the International Union of Radio Science (URSI) is in charge of developing and improving the IRI model. As requested by COSPAR and URSI, IRI is an empirical model being based on most of the available and reliable data sources for the ionospheric plasma. The paper describes the latest version of the model and reviews efforts towards future improvements, including the development of new global models for the F2 peak density and height, and a new approach to describe the electron density in the topside and plasmasphere. Our emphasis will be on the electron density because it is the IRI parameter most relevant to geodetic techniques and studies. Annual IRI meetings are the main venue for the discussion of IRI activities, future improvements, and additions to the model. A new special IRI task force activity is focusing on the development of a real-time IRI (RT-IRI) by combining data assimilation techniques with the IRI model. A first RT-IRI task force meeting was held in 2009 in Colorado Springs. We will review the outcome of this meeting and the plans for the future. The IRI homepage is at http://www.IRI.gsfc.nasa.gov

Ethical considerations for planetary protection in space exploration: a workshop.

PubMed

Rummel, J D; Race, M S; Horneck, G

2012-11-01

With the recognition of an increasing potential for discovery of extraterrestrial life, a diverse set of researchers have noted a need to examine the foundational ethical principles that should frame our collective space activities as we explore outer space. A COSPAR Workshop on Ethical Considerations for Planetary Protection in Space Exploration was convened at Princeton University on June 8-10, 2010, to examine whether planetary protection measures and practices should be extended to protect planetary environments within an ethical framework that goes beyond "science protection" per se. The workshop had been in development prior to a 2006 NRC report on preventing the forward contamination of Mars, although it responded directly to one of the recommendations of that report and to several peer-reviewed papers as well. The workshop focused on the implications and responsibilities engendered when exploring outer space while avoiding harmful impacts on planetary bodies. Over 3 days, workshop participants developed a set of recommendations addressing the need for a revised policy framework to address "harmful contamination" beyond biological contamination, noting that it is important to maintain the current COSPAR planetary protection policy for scientific exploration and activities. The attendees agreed that there is need for further study of the ethical considerations used on Earth and the examination of management options and governmental mechanisms useful for establishing an environmental stewardship framework that incorporates both scientific input and enforcement. Scientists need to undertake public dialogue to communicate widely about these future policy deliberations and to ensure public involvement in decision making. A number of incremental steps have been taken since the workshop to implement some of these recommendations.

Prognostic value of two tumour staging classifications in patients with sinonasal mucosal melanoma.

PubMed

Houette, A; Gilain, L; Mulliez, A; Mom, T; Saroul, N

2016-11-01

Sinonasal mucosal melanoma is a rare disease associated with a very poor prognosis. The purpose of this study was to assess the prognostic value of the 2 staging systems published in the literature for these tumours: the American Joint Committee on Cancer (AJCC) Cancer Staging Manual for mucosal melanoma of the head and neck published in 2009 (7th edition) and the AJCC Cancer Staging Manual for cancers of the nasal cavity and paranasal sinuses published in 2002 (6th edition) and the prognostic value of tumour site, either limited to the nasal cavities or with paranasal sinus invasion. A retrospective study was conducted on 18 patients treated between August 1998 and June 2014. Each lesion was staged according to the AJCC Cancer Staging Manual 2002 and 2009 and the following data were collected: age, sex, tumour site, initial symptoms, treatment modalities, follow-up, recurrences and overall survival. Patient survival, from the date of discovery of the melanoma until death, was analysed by Kaplan-Meier survival curves and between-group comparison of survival was performed with a log rank test. The mean age at diagnosis was 72 years (range: 54-94) and the cohort comprised 11 women and 7 men. The median overall survival was 80 months, the 1-year overall survival was 82.6% and the 5-year overall survival was 54.5%. The AJCC 2002 staging system presented a statistically significant prognostic value (P=0.0476), while no statistically significant prognostic value was observed for the AJCC 2009 staging system (P=0.108). Paranasal sinus invasion was significantly associated with a poor prognosis (P=0.0039). This study demonstrates the superiority of the non-specific AJCC 2002 Cancer Staging Manual. Medical and surgical management must take paranasal sinus invasion into account, as it constitutes a major prognostic factor. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Fine-needle aspiration cytology: its origin, development, and present status with special reference to a developing country, India.

PubMed

Das, Dilip K

2003-06-01

Fine-needle aspiration cytology (FNAC) was performed on a large scale at Memorial Hospital, New York, during the 1930s, but during the ensuing years, it did not gain much encouragement in United States. The technique had a resurgence in Scandinavia during the 1950s and 1960s, where it flourished before spreading to other parts of the world. It had also a revival in the United States, which contributed enormously to this tool in each and every aspect. The status of FNA during 1966-2002 was assessed through review of MEDLINE search data on FNA and its correlation with World Bank website data on classification of countries. A total of 849 journals published 5,609 articles on FNA over a period of 37 years. Both the number of publishing journals and the number of published articles on FNA were low during the 1960s (3.5 +/- 0.58 and 4.0 +/- 0.82, respectively) and 1970s (20.3 +/- 14.72 and 25.0 +/- 20.54, respectively), but their number increased sharply from the 1980s onward (78.2 +/- 25.65 and 147.2 +/- 66.89, respectively, during the 1980s, 126.2 +/- 11.94 and 301.4 +/- 35.99, respectively, during the 1990s, and 113.3 +/- 36.46 and 287.3 +/- 85.93, respectively, during the 2000s). The difference between the decades of 1960s-2000s, with respect to the number of publishing journals and published articles, was highly significant (P < 0.0001). Only 90 (10.6%) of the journals were from the arena of pathology and its branches. The remaining journals belonged to various other disciplines of medicine; a small fraction were even from the veterinary sciences. Ten journals, including three in the field of cytopathology, published 2,448 (43.6%) of the total articles on FNA. During 1987-2002, 46 (29.7%) of the 155 developing nations published articles on FNA, whereas 28 (52.8%) of the developed (high-income economies) countries did so, the difference being highly significant (P = 0.0044). The total number of publications from high-income economies was 3,124 (195.3 per year), as opposed to 772 (48.3 per year) from the developing world. The number of articles published from the developing nations (16.8 +/- 52.21) was significantly lower as compared with that from the high-income economies (111.6 +/- 242.03) (P = 0.005). Except for infectious diseases, the high-income economies had a definite edge over the developing nations in the absolute number of publications from each and every site/organ. However, when the frequency of publications on various organs/sites was compared between the two groups, it was found that the number of articles from high-income economies was significantly higher with respect to breast diseases (P < 0.001) and pancreatic lesions (P = 0.0158), whereas the developing nations published more frequently on small round cell tumors (excluding exclusive reports on lymphoma) and infectious diseases (P < 0.001). In India, FNAC was first introduced during the early 1970s and spread to different parts through formal teaching under the postgraduate curriculum in pathology and by conducting workshops and continuing medical education program for pathologists, surgeons/physicians, and radiologists. FNAC is now practiced in all medical colleges, in big public sector hospitals, and even in private clinics and laboratories. The number of centers practicing FNAC increased sharply during 1980s, as evident from the response of 69 laboratories in various parts of India to a questionnaire. As of 1998, 55.9% of the laboratories performed >/=1,000 cases of FNA per year. In 46% of the centers, pathologists alone performed the FNAC, whereas in 51%, they performed it in collaboration with radiologists and surgeons. Disposable syringes and needles were used in all the centers, but syringe holders were used in only in 61% of centers. In 86% of laboratories, two or more routine stains were used, and one or more ancillary techniques on fine-needle aspirates were adopted in 72.5% centers. Of the 772 publications from the developing world during 1987-2002, India alone contributed to 374 (48.4%). During 1975-2002, 154 articles on FNA were published needles were used in all the centers, but syringe holders were used in only in 61% of centers. In 86% of laboratories, two or more routine stains were used, and one or more ancillary techniques on fine-needle aspirates were adopted in 72.5% centers. Of the 772 publications from the developing world during 1987-2002, India alone contributed to 374 (48.4%). During 1975-2002, 154 articles on FNA were published in 15 indexed Indian journals.

A Consensus at Last: American Civil War Texts and the Topics that Dominate the College Classroom

ERIC Educational Resources Information Center

Rogers, William B.; Martyn, Terese

2008-01-01

The number of books published on the American Civil War has been remarkable. According to the 2002 edition of "The Civil War Desk Reference" by the Library of Congress," at least 50,000 books and pamphlets on the Civil War have been published since the 1860's." Consequently, history instructors have to confront the difficult task of selecting a…

Meeting on the Physical Oceanography of Sea Straits (2nd). Held in Villefanche-sur-Mer, France on 15-19 April 2002

DTIC Science & Technology

2002-04-19

apply in the presence of mixing and dissipation. Some people prefer to think of control in terms of information transmission (wave propagation...2002, in preparation. Officer. C . B., Physical Oceanography of Estuaries. John Wiley and Sons, 1976. Pawlak, G. & Armi, L. Vortex dynamics in a...few decades. Hard thinking , new obser- 1964. vational techniques. and increasingly sophisticated models Gerdes. F, C . Garrett, and D. Farmer, On

UF Biomotor/Biosensor Nanotechnologies

DTIC Science & Technology

2007-09-25

compared to experimental data ( Bernheim -Groswasser et al. 2002; Wiesner et al. 2003). Plot from (Dickinson and Purich 2006). 44 Task 5 - Direct real-time...13. Bernheim -Groswasser A, Wiesner S, Golsteyn RM, Carlier ME, Sykes C. 2002. The dynamics of actin-based motility depend on surface parameters

Number and impact of published scholarly works by pharmacy practice faculty members at accredited US colleges and schools of pharmacy (2001-2003).

PubMed

Coleman, Craig I; Schlesselman, Lauren S; Lao, Eang; White, C Michael

2007-06-15

To evaluate the quantity and quality of published literature conducted by pharmacy practice faculty members in US colleges and schools of pharmacy for the years 2001-2003. The Web of Science bibliographic database was used to identify publication citations for the years 2001-2003, which were then evaluated in a number of different ways. Faculty members were identified using American Association of Colleges of Pharmacy rosters for the 2000-2001, 2001-2002, and 2002-2003 academic years. Two thousand three hundred seventy-four pharmacy practice faculty members generated 1,896 publications in Web of Science searchable journals. A small number of faculty members (2.1%) were responsible for a large proportion of publications (30.6%), and only 4.9% of faculty members published 2 or more publications in these journals per year. The average impact factor for the top 200 publications was 7.6. Pharmacy practice faculty members contributed substantially to the biomedical literature and their work has had an important impact. A substantial portion of this work has come from a small subset of faculty members.

Findings in 2002 from a help wanted index of job advertisements: is the job-market shortage of diagnostic radiologists easing?

PubMed

Saketkhoo, Daniel D; Sunshine, Jonathan H; Covey, Anne M; Forman, Howard P

2003-08-01

The goal of this study is to present the most recent data on the diagnostic radiology job market in the United States using a help wanted index of job advertisements. All diagnostic radiology positions advertised in the American Journal of Roentgenology and Radiology from January through December 2002 were coded by practice type, geographic location, and subspecialty. Data were compared with the previously published results from 1991 through 2001. From January through December 2002, 5117 positions were advertised for diagnostic radiologists, representing a 10.4% decrease from 2001. The 12-month rolling average of job advertisements peaked at 488 in February 2002 and dropped to 432 by December 2002, a level not seen since August 2000. In 2002, 42.7% of positions advertised were academic, representing a steady increase from 34.0% in 1999. When comparing the 4-year periods 1999-2002 and 1995-1998, a statistically significant proportional increase was found for positions advertised in the Midwest. Statistically significant relative increases were also observed for the subspecialties of abdominal radiology, mammography, neuroradiology, pediatric radiology, chest radiology, and nuclear medicine. Statistically significant relative decreases were seen in general and vascular and interventional positions. The absolute demand for diagnostic radiologists nationwide appears to have stabilized during 2002, albeit at a level much higher than in previous years, and may be decreasing. A split seems to have appeared in the market between academia and private practice. Current policy should be directed toward increasing the supply of diagnostic radiologists, especially academicians.

Use of nerve conduits for peripheral nerve injury repair: A Web of Science-based literature analysis.

PubMed

Nan, Jinniang; Hu, Xuguang; Li, Hongxiu; Zhang, Xiaonong; Piao, Renjing

2012-12-15

To identify global research trends in the use of nerve conduits for peripheral nerve injury repair. Numerous basic and clinical studies on nerve conduits for peripheral nerve injury repair were performed between 2002-2011. We performed a bibliometric analysis of the institutions, authors, and hot topics in the field, from the Web of Science, using the key words peripheral nerve and conduit or tube. peer-reviewed published articles on nerve conduits for peripheral nerve injury repair, indexed in the Web of Science; original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items. articles requiring manual searching or telephone access; documents not published in the public domain; and several corrected papers. (a) Annual publication output; (b) publication type; (c) publication by research field; (d) publication by journal; (e) publication by funding agency; (f) publication by author; (g) publication by country and institution; (h) publications by institution in China; (i) most-cited papers. A total of 793 publications on the use of nerve conduits for peripheral nerve injury repair were retrieved from the Web of Science between 2002-2011. The number of publications gradually increased over the 10-year study period. Articles constituted the main type of publication. The most prolific journals were Biomaterials, Microsurgery, and Journal of Biomedical Materials Research Part A. The National Natural Science Foundation of China supported 27 papers, more than any other funding agency. Of the 793 publications, almost half came from American and Chinese authors and institutions. Nerve conduits have been studied extensively for peripheral nerve regeneration; however, many problems remain in this field, which are difficult for researchers to reach a consensus.

49 CFR 192.809 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of individuals performing covered tasks by October 28, 2002. (c) Work performance history review may be used as a sole evaluation method for individuals who were performing a covered task prior to October 26, 1999. (d) After October 28, 2002, work performance history may not be used as a sole...

49 CFR 195.509 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... state agency. (b) Operators must complete the qualification of individuals performing covered tasks by October 28, 2002. (c) Work performance history review may be used as a sole evaluation method for individuals who were performing a covered task prior to October 26, 1999. (d) After October 28, 2002, work...

The Flight Control System of the Hovereye (Trademark) VTOL UAV

DTIC Science & Technology

2007-05-01

10 RTO-MP-AVT-146 UNCLASSIFIED/UNLIMITED UNCLASSIFIED/UNLIMITED Envelope protection -+ SISO linear Controllers α_dotc Cinematic decoupler ωc αest...T. Ward, “Reentry Vehicle Flight Controls Design Guidelines: Dynamic Inversion”, NASA/TP-2002–210771, March 2002 [14] Pollini, L., Innocenti, M

Reluctant Samurai? Partnering with Japan to Combat Terrorism

DTIC Science & Technology

2006-04-01

Strategy of the United States of America (Washington, D.C.: Government Printing Office, 2002), 7. 5 Saunders, 151. 6 Inazo Nitobe , Bushido: The Soul...Officer, March 2002, 38-41. Napoleoni, Loretta. Terror Incorporated. New York: Seven Stories Press, 2005. Nitobe , Inazo . Bushido: The Soul of Japan

Maintenance Trades Guidelines

ERIC Educational Resources Information Center

Weidner, Theodore J.

2008-01-01

In 2002, APPA published "Maintenance Staffing Guidelines for Educational Facilities," the first building maintenance trades staffing guideline designed to assist educational facilities professionals with their staffing needs. addresses how facilities professionals can determine the appropriate size and mix of their organization. Contents…

Qualitative research publication rates in top-ranked nursing journals: 2002-2011.

PubMed

Gagliardi, Anna R; Umoquit, Muriah; Webster, Fiona; Dobrow, Mark

2014-01-01

Journal publication is the traditional means of disseminating research. Few top-ranked general medical and health services and policy research journals publish qualitative research. This study examined qualitative research publication rates in top-ranked nursing journals with varying characteristics (general vs. specialty focus, number of issues per year) and compared publication rates with those previously reported for journals in related fields. A bibliometric approach was used to identify and quantify qualitative articles published in 10 top-ranked nursing journals from 2002 to 2011. The percentage of qualitative empirical studies varied within and across nursing journals with no apparent association with journal characteristics. Although variable, qualitative research appears more common in high-ranking nursing journals than in general medical and health services and policy research journals. Examining factors that contribute to inconsistent rates may identify strategies to optimize qualitative research reporting and publication.

Water Resources Data, Georgia, 2002--Volume 1: Continuous water-level, streamflow, water-quality data, and periodic water-quality data, Water Year 2002

USGS Publications Warehouse

Hickey, Andrew C.; Kerestes, John F.; McCallum, Brian E.

2002-01-01

Water resources data for the 2002 water year for Georgia consists of records of stage, discharge, and water quality of streams; and the stage and contents of lakes and reservoirs published in two volumes in a digital format on a CD-ROM. Volume one of this report contains water resources data for Georgia collected during water year 2002, including: discharge records of 154 gaging stations; stage for 165 gaging stations; precipitation for 105 gaging stations; information for 20 lakes and reservoirs; continuous water-quality records for 27 stations; the annual peak stage and annual peak discharge for 72 crest-stage partial-record stations; and miscellaneous streamflow measurements at 50 stations, and miscellaneous water-quality data recorded by the NAWQA program in Georgia. Volume two of this report contains water resources data for Georgia collected during calendar year 2002, including continuous water-level records of 155 ground-water wells and periodic records at 132 water-quality stations. These data represent that part of the National Water Data System collected by the U.S. Geological Survey and cooperating State and Federal agencies in Georgia.

Patterns and correlates of parental and formal sexual and reproductive health communication for adolescent women in the United States, 2002-2008.

PubMed

Stidham-Hall, Kelli; Moreau, Caroline; Trussell, James

2012-04-01

To investigate patterns and correlates of sexual and reproductive health (SRH) communication among adolescent women in the United States between 2002 and 2008. We used data with regard to adolescent women (aged 15-19 years) from the National Survey of Family Growth (between 2002 and 2006-2008, n = 2,326). Multivariate analyses focused on sociodemographic characteristics and SRH communication from parental and formal sources. Seventy-five percent of adolescent women had received parental communication on abstinence (60%), contraception (56%), sexually transmitted infections (53%), and condoms (29%); 9% received abstinence-only communication. Formal communication (92%) included abstinence (87%) and contraceptive (71%) information; 66% received both, whereas 21% received abstinence-only. Between 2002 and 2006-2008, parental (not formal) communication increased (7%, p < .001), including the abstinence communication (4%, p = .03). Age, sexual experience, education, mother's education, and poverty were positively associated with SRH communication. Between 2002 and 2008, receipt of parental SRH communication, especially abstinence, was increasingly common among United States adolescents. Strategies to promote comprehensive communication may improve adolescents' SRH outcomes. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

Effect of Bioaerosol on the Release of Iodine from Iodine Treated Filters

DTIC Science & Technology

2011-12-01

bacteriophage aerosols”, Journal of Applied Microbiology , 107, 1912–1923. (7) Prescott , L.M., Harley, J.P. and Klein, D.A. (2002). Microbiology . 5th Ed... Prescott et al., 2002; Golmohammadi et al., 1993). MS2 is hydrophilic and negatively charged (Valegård et al, 1990). 2.2. Experimental system Figure 1...and ultrafine virus aerosol particles. Journal of Applied Microbiology , 99, 1422-1434. (6) Lee, J.H., Wu, C.Y., Lee, C.N., Anwar, D., Wysocki, K.M

High Temperature Resistant Organic/Inorganic Hybrid Polymers: An Architectural Study

DTIC Science & Technology

2007-04-18

period. List the papers, including journal references: Iyer, P.; Beck , J. B.; Rowan, S.J., Weder C. Synthesis and Optical Properties of Metallo...publication and to a new grant being submitted in response to the ARO BAA W911NF-06-R-0005 "Basic Research Program in Chemical, Biological, Radiological...2002, 35, 3315. (e) Ishaque, M.; Agarwal, S.; Greiner, A. E-Polymers 2002, Art. No. 31. (15) Beck , B.J.; Kokil, A.; Ray, D.; Rowan, S.J.; Weder, C

Changes in body mass index and the prevalence of obesity during 1994-2008: repeated cross-sectional surveys and longitudinal analyses. The Tromsø Study.

PubMed

Jacobsen, Bjarne K; Aars, Nils Abel

2015-06-12

To determine the mean body mass index (BMI, kg/m(2)) and prevalence of low weight (BMI<20) and obesity (BMI ≥ 30) in 3 population-based surveys, and to describe the longitudinal changes during 1994-2008 in mean BMI, and the prevalence of low weight and obesity. A population study in Tromsø, Norway. A total of 29,688 different participants in 1 or more of 3 surveys (1994-1995, 2001-2002 and 2007-2008). Longitudinal analyses comprised 9845 participants aged 25-69 in 1994 who participated in the 1994-1995 and 2007-2008 surveys and 4202 men and women who participated in all 3 surveys. Mean age-specific and sex-specific BMI, prevalence of low weight and obesity, and changes in BMI and prevalence of low weight and obesity during 1994-2008, according to sex and birth cohort. The age-adjusted (ages 30-84) prevalence of obesity increased from 9.8% and 11.8% in men and women, respectively, in 1994-1995 to 20.9% and 18.5%, respectively, in 2007-2008. The increase in mean age-adjusted BMI was stronger from 1994-1995 to 2001-2002 than from 2001-2002 to 2007-2008. Longitudinal results confirmed that the change in BMI from 1994-1995 to 2001-2002 was larger (0.9 kg/m(2) (95% CI 0.8 to 1.0) in men and 1.3 kg/m(2) (95% CI 1.2 to 1.4) in women) than from 2001-2002 to 2007-2008 (0.2 kg/m(2) (95% CI 0.1 to 0.3) in men and women). The most recently born had the largest increase (p<0.001). The mean BMI and the prevalence of obesity are still increasing in Tromsø, and the increase is strongest in the youngest age groups. However, the increase in BMI was less marked in the last period (from 2001-2002 to 2007-2008) than in the first period (1994-1995 to 2001-2002). Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

The Earth's Middle Atmosphere: COSPAR Plenary Meeting, 29th, Washington, DC, 28 Aug.-5 Sep., 1992

NASA Technical Reports Server (NTRS)

Grosse, W. L. (Editor); Ghazi, A. (Editor); Geller, M. A. (Editor); Shepherd, G. G. (Editor)

1994-01-01

The conference presented the results from the Upper Atmosphere Research Satellite (UARS) in the areas of wind, temperature, composition, and energy input into the upper atmosphere. Also presented is the current status of validation of the UARS temperature and wind instruments measuring at and above the menopause. The two UARS instruments involved were the High Resolution Doppler Imager (HRDI) and the WIND Imaging Interferometer (WINDII). Papers are presented covering almost all aspects of middle atmospheric science, including dynamics, layering in the middle atmosphere, atmospheric composition, solar and geomagnetic effects, electrodynamics, and the ionosphere.

Launch summary for 1980

NASA Technical Reports Server (NTRS)

Vostreys, R. W.

1981-01-01

Sounding rockets, artificial Earth satellites, and space probes launched betweeen January 1 and December 31, 1980 are listed. Data tabulated for the rocket launchings show launching site, instruments carried, date of launch, agency rocket identification, sponsoring country, experiment discipline, peak altitude, and the experimenter or institution responsible. Tables for satellites and space probes show COSPAR designation, spacecraft name, country, launch date, epoch date, orbit type, apoapsis, periapsis and inclination period. The functions and responsibilities of the World Data Center and the areas of scientific interest at the seven subcenters are defined. An alphabetical listing of experimenters using the sounding rockets is also provided.

Middle Atmosphere Program. Handbook for MAP. Volume 31: Reference models of trace species for the COSPAR international reference atmosphere

NASA Technical Reports Server (NTRS)

Keating, G. M. (Editor)

1989-01-01

A set of preliminary reference atmosphere models of significant trace species which play important roles in controlling the chemistry, radiation budget, and circulation patterns of the atmosphere were produced. These models of trace species distributions are considered to be reference models rather than standard models; thus, it was not crucial that they be correct in an absolute sense. These reference models can serve as a means of comparison between individual observations, as a first guess in inversion algorithms, and as an approximate representation of observations for comparison to theoretical calculations.

Space life sciences: closed ecological systems: earth and space applications.

PubMed

2005-01-01

This issue contains peer-reviewed papers from a workshop on Closed Ecological Systems: Earth and Space Applications at the 35th COSPAR General Assembly in Paris, France, convened in July 2004. The contributions reflected the wide range of international work in the field, especially Europe, Russia, Japan, and the United States. The papers are arranged according to four main themes: 1) Methods of evaluation and theory of closed ecological systems; 2) Reports from recent experiments in closed ecological system facilities; 3) Bioregenerative technologies to advance degree of closure and cycling; and 4) Laboratory studies of small closed ecological systems.

From Science Reserves to Sustainable Multiple Uses beyond Earth orbit: Evaluating Issues on the Path towards Balanced Environmental Management on Planetary Bodies

NASA Astrophysics Data System (ADS)

Race, Margaret

Over the past five decades, our understanding of space beyond Earth orbit has been shaped by a succession of mainly robotic missions whose technologies have enabled scientists to answer diverse science questions about celestial bodies across the solar system. For all that time, exploration has been guided by planetary protection policies and principles promulgated by COSPAR and based on provisions in Article IX of the Outer Space Treaty of 1967. Over time, implementation of the various COSPAR planetary protection policies have sought to avoid harmful forward and backward contamination in order to ensure the integrity of science findings, guide activities on different celestial bodies, and appropriately protect Earth whenever extraterrestrial materials have been returned. The recent increased interest in extending both human missions and commercial activities beyond Earth orbit have prompted discussions in various quarters about the need for updating policies and guidelines to ensure responsible, balanced space exploration and use by all parties, regardless whether activities are undertaken by governmental or non-governmental entities. Already, numerous researchers and workgroups have suggested a range of different ways to manage activities on celestial environments (e.g, wilderness parks, exclusion zones, special regions, claims, national research bases, environmental impact assessments, etc.). While the suggestions are useful in thinking about how to manage future space activities, they are not based on any systematically applied or commonly accepted criteria (scientific or otherwise). In addition, they are borrowed from terrestrial approaches for environmental protection, which may or may not have direct applications to space environments. As noted in a recent COSPAR-PEX workshop (GWU 2012), there are no clear definitions of issues such as harmful contamination, the environment to be protected, or what are considered reasonable activity or impacts for particular locations—and over what time frames. Likewise, there are no guidelines for how to deal with the potential conflict between economic viability for commercial space activity and the need for reasonable planetary protection measures and standards. Before creating guidelines for particular locations or developing a international environmental regime for blending space exploration and use, it is advisable to have at least have a cursory overview of what lies ahead in the technical, scientific, commercial, environmental and policy realms. To develop such an overview, I undertook a preliminary analysis of the proposed activities, stakeholders, timeframes, and potential environmental impacts anticipated in coming years for robotic and human missions, particularly for the Moon and Mars. Hopefully, this type of information will be useful as the international community works towards updating policies and guidelines for responsible, balanced space exploration and use by all parties.

Strategy for the International Lunar Decade

NASA Astrophysics Data System (ADS)

Beldavs, V.; Dunlop, D.; Foing, B.

2015-10-01

LD is a global event and process for international collaboration in space initiated by the International Lunar Exploration Working Group (ILEWG), the National Space Society and the National Science Centre FOTONIKA-LV of the University of Latvia. ILD is planned for launch in 2017, the 60th anniversary of the International Geophysical Year that marked the dawn of the space age with the launch of Sputnik. ILD is envisioned as a decade long process of international collaboration with lunar exploration concurrent with development of policies, key enabling technologies and infrastructures on the Moon and in cislunar space leading towards an eventual goal of industrial development of the Moon and economic activity beyond Earth orbit[1]. This second International Lunar Decade will build on the foundations of the ILD first proposed in by the Planetary Society in 2006 at International Conference on Exploration and Utilisation of the Moon (ICEUM), was endorsed by ICEUM participants[3], and then by ILEWG, COSPAR and other organizations. Starting in 2007, the work plan included a series of recommendations for lunar exploration missions coordinated through the ILEWG agencies and COSPAR. Advances in technology such as CubeSats and 3D printing and fundamental changes in mind-set marked by initiatives such as the Google Lunar-X prize and asteroid mining ventures have made industrial development of the Moon a thinkable proposition. The ILD to be launched in 2017 is intended to set the stage for the Moon to become a wealth generating platform for human expansion into the solar system.ILD is being organized to engage existing organizations involved in space collaboration such as COSPAR, COPUOS, ISECG, technical and scientific organizations and others that address space policy, space law, space security, governance and related concerns. Additional organizations will be involved that deal with structures, ecosystems, financing, economic development and health and life support and related concerns. The Moon Treaty (1979) will be reviewed for its applicability to the development of the international regime that will be required to govern mining, industrial development and commercial activities on the Moon. ILD has already been a significant topic in several international conferences.Through this and many other conferences to follow the initial organizers expect that key organizations will see a role for their activities within the ILD process, endorse it and start to shape implementation plans. This report will focus on overall strategies for the ILD process to fully engage multiple countries and organizations building towards a shared vision through a diversity of scientific, technical and cultural perspectives. Public outreach and involvement of the public, particularly youth and schools will be an important component of the overall strategy. The activities of the International Lunar Decade Working Group can be followed at https://ildwg.wordpress.com .

The Group on Earth Observations (GEO) through 2025

NASA Astrophysics Data System (ADS)

Ryan, Barbara; Cripe, Douglas

Ministers from the Group on Earth Observations (GEO) Member governments, meeting in Geneva, Switzerland in January 2014, unanimously renewed the mandate of GEO through 2025. Through a Ministerial Declaration, they reconfirmed that GEO’s guiding principles of collaboration in leveraging national, regional and global investments and in developing and coordinating strategies to achieve full and open access to Earth observations data and information in order to support timely and knowledge-based decision-making - are catalysts for improving the quality of life of people around the world, advancing global sustainability, and preserving the planet and its biodiversity. GEO Ministers acknowledged and valued the contributions of GEO Member governments and invited all remaining Member States of the United Nations to consider joining GEO. The Ministers also encouraged all Members to strengthen national GEO arrangements, and - of particular interest to COSPAR - they highlighted the unique contributions of Participating Organizations. In this regard, ten more organizations saw their applications approved by Plenary and joined the ranks along with COSPAR to become a Participating Organization in GEO, bringing the current total to 77. Building on the efforts of a Post-2015 Working Group, in which COSPAR participated, Ministers provided additional guidance for GEO and the evolution of its Global Earth Observation System of System (GEOSS) through 2025. Five key areas of activities for the next decade include the following: 1.) Advocating for the value of Earth observations and the need to continue improving Earth observation worldwide; 2.) Urging the adoption and implementation of data sharing principles globally; 3.) Advancing the development of the GEOSS information system for the benefit of users; 4.) Developing a comprehensive interdisciplinary knowledge base defining and documenting observations needed for all disciplines and facilitate availability and accessibility of these observations to user communities; and 5.) Cultivating global initiatives tailored to meet specific user needs. The work in these five areas will build on the current GEOSS achievements and ensure that these achievements are both sustained and evolve in keeping pace with policy, technological and information changes at the global level. Certainly much has been accomplished in GEO’s first decade. Yet, more remains to be done. Many - possibly most - nations are facing challenges in operating and sustaining, not to mention expanding, their Earth observation networks. Broad, open data-sharing policies and practices are still not universally accepted and employed. And, communicating scientific results so that policy makers and the general public can understand the long term (as well as short term) impacts and implications remains challenging. GEO Members and Participating Organizations must continue to work aggressively to address each of these challenges if Earth system science is going to fully address the significant environmental issues facing the world today.

A gravitational potential finding for rotating cosmological body in the context of proto-planetary dynamics problem solving

NASA Astrophysics Data System (ADS)

Krot, Alexander M.

2008-09-01

The statistical theory for a cosmological body forming (so-called the spheroidal body model) has been proposed in [1]-[9]. Within the framework of this theory, bodies have fuzzy outlines and are represented by means of spheroidal forms [1],[2]. In the work [3], it has been investigated a slowly evolving in time process of a gravitational compression of a spheroidal body close to an unstable equilibrium state. In the papers [4],[5], the equation of motion of particles inside the weakly gravitating spheroidal body modeled by means of an ideal liquid has been obtained. Using Schwarzschild's and Kerr's metrics a consistency of the proposed statistical model with the general relativity has been shown in [6]. The proposed theory follows from the conception for forming a spheroidal body from protoplanetary nebula [7],[8]; it permits to derive the form of distribution functions for an immovable [1]-[5] and rotating spheroidal body [6]-[8] as well as their density masses and also the distribution function of specific angular momentum of the rotating uniformly spheroidal body [7],[8]. It is well-known there is not a statistical equilibrium in a gas-dust proto-planetary cloud because of long relaxation time for proto-planets formation in own gravitational field. This proto-planetary system behavior can be described by Jeans' equation in partial derivations relative to a distribution function [9]. The problem for finding a general solution of Jeans' equation is connected directly with an analytical expression for potential of gravitational field. Thus, the determination of gravitational potential is the main problem of statistical dynamics for proto-planetary system [9]. This work shows this task of proto-planetary dynamics can be solved on the basis of spheroidal bodies theory. The proposed theory permits to derive the form of gravitational potential for a rotating spheroidal body at a long distance from its center. Using the obtained analytical expression for potential of gravitational field, the gravitational strength (as well as angular momentum space function) in a remote zone of a slowly gravitational compressed rotating spheroidal body is obtained. As a result, a distribution function describing mechanical state of proto-planetary system can be found from the Jeans' equation. References: [1] Krot AM. The statistical model of gravitational interaction of particles. Uspekhi Sovremennoï Radioelektroniki (special issue "Cosmic Radiophysics", Moscow) 1996; 8: 66-81 (in Russian). [2] Krot AM. Use of the statistical model of gravity for analysis of nonhomogeneity in earth surface. Proc. SPIE's 13th Annual Intern. Symposium "AeroSense", Orlando, Florida, USA, April 5-9, 1999; 3710: 1248-1259. [3] Krot AM. Statistical description of gravitational field: a new approach. Proc. SPIE's 14th Annual Intern.Symposium "AeroSense", Orlando, Florida, USA, April 24-28, 2000; 4038: 1318-1329. [4] Krot AM. Gravidynamical equations for a weakly gravitating spheroidal body. Proc. SPIE's 15th Annual Intern. Symposium "AeroSense", Orlando, Florida, USA, April 16-20, 2001; 4394: 1271-1282. [5] Krot AM. Development of gravidynamical equations for a weakly gravitating body in the vicinity of absolute zero temperature. Proc. 53rd Intern. Astronautical Congress (IAC) - The 2nd World Space Congress-2002, Houston, Texas, USA, October 10-19, 2002; Preprint IAC-02-J.P.01: 1-11. [6] Krot AM. The statistical model of rotating and gravitating spheroidal body with the point of view of general relativity. Proc. 35th COSPAR Scientific Assembly, Paris, France, July 18-25, 2004; Abstract-Nr. COSPAR 04-A- 00162. [7] Krot A. The statistical approach to exploring formation of Solar system. Proc. European Geoscinces Union (EGU) General Assembly, Vienna, Austria, April 02-07, 2006; Geophysical Research Abstracts, vol. 8: EGU06-A- 00216, SRef-ID: 1607-7962/gra/. [8] Krot AM. The statistical model of original and evolution planets of Solar system and planetary satellities. Proc. European Planetary Science Congress, Berlin, Germany, September 18-22, 2006; Planetary Research Abstracts, ESPC2006-A-00014. [9] Krot A. On the principal difficulties and ways to their solution in the theory of gravitational condensation of infinitely distributed dust substance. Proc. XXIV IUGG General Assembly, Perugia, Italy, July 2-13, 2007; GS002 Symposium "Gravity Field", Abstract GS002-3598: 143-144.

Anthrax Vaccine as a Component of the Strategic National Stockpile: A Dilemma for Homeland Security

DTIC Science & Technology

2009-12-01

reviews . Finally, a gap analysis aids in explaining continued reliance on the old vaccine technology. To conclude... review of the writings on anthrax vaccine summarizes published sources and synthesizes a pattern, or shift, in the literature around the 1998 time...IOM, 2002, p. 208). A 2000 IOM report also determined, “there is a paucity of published peer- reviewed literature on the

Current rectification by self-assembled molecular quantum dots from first principles

NASA Astrophysics Data System (ADS)

Larade, Brian; Bratkovsky, Alexander

2003-03-01

We present results of first-principles calculations of the current rectification by self-assembled molecular quantum dots. Molecules of that kind should be synthesized with a central conjugated (narrow band-gap) part, and two peripheral saturated (wide band-gap) barrier groups of substantially different lengths L1 and L_2. The peripheral groups must end with chemical Â"anchorÂ" groups, enabling attachment of the molecule to the electrodes. In such molecules, if they are not longer than about 2-3 nm, the electron transport is likely to proceed by resonant tunneling through molecular orbitals (MO) centered on the conjugated part of the molecule (Â"quantum dotÂ") [1,2]. Generally, either LUMO (lowest unoccupied MO) or HOMO (highest occupied MO) will be most transparent to the tunneling electrons because of their different coupling to electrodes. We have studied (i) single benzene ring C6H6 [2] and (ii) naphthalene C10H8, separated from gold electrodes by alkane chains of different lengths with the use of the non-equilibrium Green's function method and self-consistent density-functional theory. The results show significant changes in electron density and potential distribution in the vicinity of molecule-electrode contact. In the case of a naphthalene quantum dot, separated from electrodes by asymmetric alkane groups (CH2)2 and (CH2)6, the I-V curve shows current rectification on the order of ˜ 10^2. [1] A.M. Bratkovsky and P.E. Kornilovitch, Phys. Rev. B (2002), to be published. [2] P. E. Kornilovitch, A.M. Bratkovsky, and R.S. Williams, Phys. Rev. B 66, 165436 (2002).

Countering Global Terrorism: Developing the Antiterrorist Capabilities of the Central Asian Militaries

DTIC Science & Technology

2004-02-01

Strategic Studies (London) and the co-editor of the book, Russian Military Reform 1992- 2002 (Frank Cass: London/Portland, 2003). v SUMMARY Political: U.S...in Anne C. Aldis and Roger N. McDermott, eds., Russian Military Reform 1992-2002, London/Portland, OR: Frank Cass, 2003, pp. 3-21. 55. The CRDF is...Challenge of “Small Wars” for the Russian Military,” in Aldis and McDermott, eds., Russian Military Reform 1992-2002, pp. 189-208. 86. Roger N

Simulated comparison of the pharmacodynamics of ciprofloxacin and levofloxacin against Pseudomonas aeruginosa using pharmacokinetic data from healthy volunteers and 2002 minimum inhibitory concentration data.

PubMed

Burgess, David S; Hall, Ronald G

2007-07-01

Until the 2002 approval of levofloxacin 750 mg QD, ciprofloxacin was the fluoroquinolone of choice against Pseudomonas aeruginosa infections. This study evaluated the AUC:MIC ratios for ciprofloxacin 400 mg BID and TID and levofloxacin 750 mg QD, all administered intravenously, against P. aeruginosa using a Monte Carlo simulation. Pharmacokinetic data for ciprofloxacin and levofloxacin and 2002 MIC distributions against P. aeruginosa were obtained from studies in healthy volunteers published in the peer-reviewed literature. Pharmacokinetic studies of each agent were identified by separate MEDLINE searches combining the MeSH heading pharmacokinetics with the generic name of the antimicrobial. Only human studies published in English between 1990 and 2001 were included. Included studies also had to meet 3 minimum criteria: evaluation of clinically relevant dosing regimens, use of rigorous study methods, and provision of mean (SD) values for the pharmacokinetic parameters of interest. When multiple studies met these criteria, a single study was selected for each antimicrobial regimen. Pharmacodynamic analysis was performed using a Monte Carlo simulation of 10,000 patients by integrating the pharmacokinetic parameters, their variability, and 2002 MIC distributions for each antimicrobial regimen. The probability of target attainment was determined for each regimen for an AUC:MIC ratio from 0 to 300. A > or =90% probability of target attainment was considered satisfactory. For ciprofloxacin 400 mg TID and levofloxacin 750 mg QD, the AUC:MIC ratio at the corresponding 2002 Clinical Laboratory Standards Institute break points of 1 and 2 microg/mL were 33 and 34, respectively. The probabilities of target attainment for a free AUC:MIC ratio >90 (equivalent to a total AUC:MIC ratio > or =125) were 47% for ciprofloxacin 400 mg BID, 54% for ciprofloxacin 400 mg TID, and 48% for levofloxacin 750 mg QD. When pharmacokinetic data from healthy volunteers and 2002 MIC data were used, none of the simulated fluoroquinolone regimens achieved a high likelihood of target attainment against P. aeruginosa.

24 CFR 2002.25 - Administrative review.

Code of Federal Regulations, 2010 CFR

2010-04-01

... INFORMATION TO THE PUBLIC § 2002.25 Administrative review. (a) Review is available only from a written denial... should clearly indicate that the subject is a Freedom of Information Act request for review. (c) Review... counsel for the Office of Inspector General. (d) The time of receipt for processing of a request for...

Changes in alcohol consumption: United States, 2001-2002 to 2012-2013.

PubMed

Dawson, Deborah A; Goldstein, Risë B; Saha, Tulshi D; Grant, Bridget F

2015-03-01

Documenting changes in alcohol consumption is critical for assessing future health service and alcohol treatment needs, evaluating efforts to modify drinking behavior and understanding the impact of shifting demographics and social norms. For the period since 2000, published data on drinking trends have been scarce and inconsistent. Using data from two large, nationally representative surveys of U.S. adults (2001-2002 and 2012-2013) that contained virtually identical questions on consumption, we assessed differences by period in the prevalence of drinking, volume of intake, frequency of drinking and prevalence of ≥monthly heavy episodic drinking (HED) and determined whether changes in consumption were consistent across beverage types and in population subgroups. Between 2001-2002 and 2012-2013, the prevalence of drinking increased, as did volume and frequency of drinking and prevalence of ≥monthly HED among drinkers. Increases were greater for women than men for all measures and smaller among the formerly married for consumption among drinkers. The increase in overall drinking prevalence was magnified among all race-ethnic minorities, whereas the increase in ≥monthly HED was magnified only among Blacks (all relative to Whites). Our findings are suggestive of a "wetter" drinking climate in 2012-2013 than in 2001-2002, indicating the need for continued and expanded efforts to prevent chronic and episodic heavy alcohol consumption. Given the across-the-board increases in alcohol consumption in recent years, policy efforts that address drinking at the population level are supported, even if specific drinking behaviors and subgroups of drinkers are additionally targeted for individualized approaches. Published by Elsevier Ireland Ltd.

Long-term changes in mollisol organic carbon and nitrogen.

PubMed

David, Mark B; McIsaac, Gregory F; Darmody, Robert G; Omonode, Rex A

2009-01-01

Conversions of Mollisols from prairie to cropland and subsequent changes in crop production practices in the Midwestern USA have resulted in changes in soil organic matter. Few studies have used archived samples, long-term resampling of soils to a depth of 1 m, and space for time studies to document these changes. We resampled soils by depth (0-100 cm) in fields at 19 locations in central Illinois on poorly drained Mollisols that were in corn (Zea mays L.) and soybean (Glycine max L. Merr.) rotations, were tile drained, and had no known history of manure application in recent decades. Three fields were paired with virgin prairie remnants, two had grass borders that were sampled, and 16 had been previously sampled in 1901 to 1904 or 1957 under various land uses (virgin prairie, cultivation, grass cover). The soils had large amounts of C and N in the profile, with mean values of 175 [corrected] Mg C ha(-1) and 16.1 Mg N ha(-1) for the 18 cultivated fields sampled in 2001 and 2002. We confirmed a large reduction in organic C and total N pools from conversion of prairies to annual cultivation and artificial drainage and documented no change in these organic matter pools of cultivated soils during the period of synthetic fertilizer use (1957--2002). Cultivated fields had soil C and N concentrations typically 30 to 50% less than virgin prairie soils. Smaller but significant declines in C and N concentrations were found when comparing 1900s cultivated fields to concentrations in 2002, after another 100 yr of cultivation, and in comparing 1957 grass covered fields that had been converted to annual cultivation before 2002. The reduction in organic matter after cultivation of prairies occurred mostly in the top 50 cm of soil, with evidence of translocation of C and N from these upper layers to the 50- to 100-cm depth, possibly enhanced by tile drainage. For these Mollisols, declines in organic matter were likely completed by the 1950s, with organic matter pools in a steady state under the production practices in place from the late 1950s through 2002.

A Sabin 3-Derived Poliovirus Recombinant Contained a Sequence Homologous with Indigenous Human Enterovirus Species C in the Viral Polymerase Coding Region†

PubMed Central

Arita, Minetaro; Zhu, Shuang-Li; Yoshida, Hiromu; Yoneyama, Tetsuo; Miyamura, Tatsuo; Shimizu, Hiroyuki

2005-01-01

Outbreaks of poliomyelitis caused by circulating vaccine-derived polioviruses (cVDPVs) have been reported in areas where indigenous wild polioviruses (PVs) were eliminated by vaccination. Most of these cVDPVs contained unidentified sequences in the nonstructural protein coding region which were considered to be derived from human enterovirus species C (HEV-C) by recombination. In this study, we report isolation of a Sabin 3-derived PV recombinant (Cambodia-02) from an acute flaccid paralysis (AFP) case in Cambodia in 2002. We attempted to identify the putative recombination counterpart of Cambodia-02 by sequence analysis of nonpolio enterovirus isolates from AFP cases in Cambodia from 1999 to 2003. Based on the previously estimated evolution rates of PVs, the recombination event resulting in Cambodia-02 was estimated to have occurred within 6 months after the administration of oral PV vaccine (99.3% nucleotide identity in VP1 region). The 2BC and the 3Dpol coding regions of Cambodia-02 were grouped into the genetic cluster of indigenous coxsackie A virus type 17 (CAV17) (the highest [87.1%] nucleotide identity) and the cluster of indigenous CAV13-CAV18 (the highest [94.9%] nucleotide identity) by the phylogenic analysis of the HEV-C isolates in 2002, respectively. CAV13-CAV18 and CAV17 were the dominant HEV-C serotypes in 2002 but not in 2001 and in 2003. We found a putative recombination between CAV13-CAV18 and CAV17 in the 3CDpro coding region of a CAV17 isolate. These results suggested that a part of the 3Dpol coding region of PV3(Cambodia-02) was derived from a HEV-C strain genetically related to indigenous CAV13-CAV18 strains in 2002 in Cambodia. PMID:16188967

Mediagraphy: Print and Nonprint Resources.

ERIC Educational Resources Information Center

Burdett, Anna E.

2003-01-01

Lists media-related journals, books, ERIC documents, journal articles, and nonprint resources published in 2001-2002. The annotated entries are classified under the following headings: artificial intelligence; computer assisted instruction; distance education; educational research; educational technology; information science and technology;…

The new ISO 6579-1: A real horizontal standard for detection of Salmonella, at last!

PubMed

Mooijman, Kirsten A

2018-05-01

Up to 2016, three international standard methods existed for the detection of Salmonella spp. in food, animal feed and samples from the primary production stage: ISO 6785:2001 for milk and milk products, ISO 6579:2002 for (other) food and animal feed and Annex D of ISO 6579:2007 for samples from the primary production stage. In 2009, an ISO/CEN working group started with the revision of ISO 6579:2002 with two main aims: combining the three aforementioned standards in one document and improving the information in ISO 6579:2002. Additionally it was decided to split ISO 6579 into three parts, where part 1 describes the detection, part 2 the enumeration by mini-MPN (published in 2012) and part 3 the serotyping of Salmonella (published in 2014). This paper describes the experiments and choices made for improving the part on detection of Salmonella (ISO 6579-1). The final voting stage on (draft) ISO 6579-1 was finished by the end of December 2016, with a positive outcome. Finally, a real horizontal standard became available for detection of Salmonella in food, animal feed, environmental samples in the area of food production and food handling and in samples from the primary production stage in 2017. Copyright © 2017 Elsevier Ltd. All rights reserved.

Bounding the risk of crew loss following orbital debris penetration of the International Space Station at assembly stages 1J and 1E.

PubMed

Evans, S; Lewis, H; Williamsen, J; Evans, H; Bohl, W

2004-01-01

Orbital debris impacts on the International Space Station occur frequently. To date, none of the impacting particles has been large enough to penetrate manned pressurized volumes. We used the Manned Spacecraft Crew Survivability code to evaluate the risk to crew of penetrations of pressurized modules at two assembly stages: after Flight 1J, when the pressurized elements of Kibo, the Japanese Experiment Module, are present, and after Flight 1E, when the European Columbus Module is present. Our code is a Monte-Carlo simulation of impacts on the Station that considers several potential event types that could lead to crew loss. Among the statistics tabulated by the program is the probability of death of one or more crew members in the event of a penetration, expressed as the risk factor, R. This risk factor is dependent on details of crew operations during both ordinary circumstances and decompression emergencies, as well as on details of internal module configurations. We conducted trade studies considering these procedure and configuration details to determine the bounds on R at the 1J and 1E stages in the assembly sequence. Here we compare the R-factor bounds, and procedures could that reduce R at these stages. Published by Elsevier Ltd on behalf of COSPAR.

Overview of atmospheric ionizing radiation (AIR) research: SST-present

NASA Technical Reports Server (NTRS)

Wilson, J. W.; Goldhagen, P.; Rafnsson, V.; Clem, J. M.; De Angelis, G.; Friedberg, W.

2003-01-01

The Supersonic Transport (SST) program, proposed in 1961, first raised concern for the exposure of pregnant occupants by solar energetic particles (SEP), and neutrons were suspected to have a main role in particle propagation deep into the atmosphere. An eight-year flight program confirmed the role of SEP as a significant hazard and of the neutrons as contributing over half of the galactic cosmic ray exposures, with the largest contribution from neutrons above 10 MeV. The FAA Advisory Committee on the Radiobiological Aspects of the SST provided operational requirements. The more recent lowering of ICRP-recommended exposure limits (1990) with the classification of aircrew as "radiation workers" renewed interest in GCR background exposures at commercial flight altitudes and stimulated epidemiological studies in Europe, Japan, Canada and the USA. The proposed development of a High Speed Civil Transport (HSCT) required validation of the role of high-energy neutrons, and this resulted in ER-2 flights at solar minimum (June 1997) and studies on effects of aircraft materials on interior exposures. Recent evaluation of health outcomes of DOE nuclear workers resulted in legislation for health compensation in year 2000 and recent European aircrew epidemiological studies of health outcomes bring renewed interest in aircraft radiation exposures. As improved radiation models become available, it is imperative that a corresponding epidemiological program of US aircrew be implemented. Published by Elsevier Ltd on behalf of COSPAR.

Bounding the risk of crew loss following orbital debris penetration of the International Space Station at assembly stages 1J and 1E

NASA Technical Reports Server (NTRS)

Evans, S.; Lewis, H.; Williamsen, J.; Evans, H.; Bohl, W.

2004-01-01

Orbital debris impacts on the International Space Station occur frequently. To date, none of the impacting particles has been large enough to penetrate manned pressurized volumes. We used the Manned Spacecraft Crew Survivability code to evaluate the risk to crew of penetrations of pressurized modules at two assembly stages: after Flight 1J, when the pressurized elements of Kibo, the Japanese Experiment Module, are present, and after Flight 1E, when the European Columbus Module is present. Our code is a Monte-Carlo simulation of impacts on the Station that considers several potential event types that could lead to crew loss. Among the statistics tabulated by the program is the probability of death of one or more crew members in the event of a penetration, expressed as the risk factor, R. This risk factor is dependent on details of crew operations during both ordinary circumstances and decompression emergencies, as well as on details of internal module configurations. We conducted trade studies considering these procedure and configuration details to determine the bounds on R at the 1J and 1E stages in the assembly sequence. Here we compare the R-factor bounds, and procedures could that reduce R at these stages. Published by Elsevier Ltd on behalf of COSPAR.

Investigation on contribution of neutron monitor data to estimation of aviation doses.

PubMed

Kákona, M; Ploc, O; Kyselová, D; Kubančák, J; Langer, R; Kudela, K

2016-11-01

Recently, many efforts have appeared to routinely measure radiation exposure (RE) of aircraft crew due to cosmic rays (CR). On the other hand real-time CR data measured with the ground based neutron monitors (NMs) are collected worldwide and available online. This is an opportunity for comparison of long-term observations of RE at altitudes of about 10km, where composition and energy spectra of secondary particles differ from those on the ground, with the data from NMs. Our contribution presents examples of such type of comparison. Analysis of the silicon spectrometer Liulin measurements aboard aircraft is presented over the period May-September 2005 and compared with data from a single NM at middle latitude. While extreme solar driven events observed by NMs have clearly shown an impact on dosimetric characteristics as measured on the airplanes, the transient short time effects in CR of smaller amplitude have been not studied extensively in relation to RE. For the period May-September 2005, when aircraft data become available and several Forbush decreases (FDs) are observed on the ground, a small improvement in the correlation between the dose measured and multiple linear regression fit based on two key parameters (altitude and geomagnetic cut-off rigidity), is obtained, if the CR intensity at a single NM is added into the scheme. Copyright © 2016 The Committee on Space Research (COSPAR). Published by Elsevier Ltd. All rights reserved.

Mapping of the Moon by Clementine

USGS Publications Warehouse

McEwen, A.S.; Robinson, M.S.

1997-01-01

The "faster, cheaper, better" Clementine spacecraft mission mapped the Moon from February 19 to May 3, 1994. Global coverage was acquired in 11 spectral bandpasses from 415 to 2792 nm and at resolutions of 80-330 m/pixel; a thermal-infrared camera sampled ???20% of the surface; a high-resolution camera sampled selected areas (especially the polar regions); and a lidar altimeter mapped the large-scale topography up to latitudes of ??75??. The spacecraft was in a polar, elliptical orbit, 400-450 km periselene altitude. Periselene latitude was -28.5?? for the first month of mapping, then moved to +28.5??. NASA is supporting the archiving, systematic processing, and analysis of the ???1.8 million lunar images and other datasets. A new global positional network has been constructed from 43,000 images and ???0.5 million match points; new digital maps will facilitate future lunar exploration. In-flight calibrations now enable photometry to a high level of precision for the uv-visible CCD camera. Early science results include: (1) global models of topography, gravity, and crustal thicknesses; (2) new information on the topography and structure of multiring impact basins; (3) evidence suggestive of water ice in large permanent shadows near the south pole; (4) global mapping of iron abundances; and (5) new constraints on the Phanerozoic cratering rate of the Earth. Many additional results are expected following completion of calibration and systematic processing efforts. ?? 1997 COSPAR. Published by Elsevier Science Ltd.

Overview of atmospheric ionizing radiation (AIR) research: SST-present.

PubMed

Wilson, J W; Goldhagen, P; Rafnsson, V; Clem, J M; De Angelis, G; Friedberg, W

2003-01-01

The Supersonic Transport (SST) program, proposed in 1961, first raised concern for the exposure of pregnant occupants by solar energetic particles (SEP), and neutrons were suspected to have a main role in particle propagation deep into the atmosphere. An eight-year flight program confirmed the role of SEP as a significant hazard and of the neutrons as contributing over half of the galactic cosmic ray exposures, with the largest contribution from neutrons above 10 MeV. The FAA Advisory Committee on the Radiobiological Aspects of the SST provided operational requirements. The more recent lowering of ICRP-recommended exposure limits (1990) with the classification of aircrew as "radiation workers" renewed interest in GCR background exposures at commercial flight altitudes and stimulated epidemiological studies in Europe, Japan, Canada and the USA. The proposed development of a High Speed Civil Transport (HSCT) required validation of the role of high-energy neutrons, and this resulted in ER-2 flights at solar minimum (June 1997) and studies on effects of aircraft materials on interior exposures. Recent evaluation of health outcomes of DOE nuclear workers resulted in legislation for health compensation in year 2000 and recent European aircrew epidemiological studies of health outcomes bring renewed interest in aircraft radiation exposures. As improved radiation models become available, it is imperative that a corresponding epidemiological program of US aircrew be implemented. Published by Elsevier Ltd on behalf of COSPAR.

The ISECG Science White Paper - A Scientific Perspective on the Global Exploration Roadmap

NASA Astrophysics Data System (ADS)

Bussey, David B.; Worms, Jean-Claude; Spiero, Francois; Schlutz, Juergen; Ehrenfreund, Pascale

2016-07-01

Future space exploration goals call for sending humans and robots beyond low Earth orbit and establishing sustained access to destinations such as the Moon, asteroids and Mars. Space agencies participating in the International Space Exploration Coordination Group (ISECG) are discussing an international approach for achieving these goals, documented in ISECG's Global Exploration Roadmap (GER). The GER reference scenario reflects a step-wise evolution of critical capabilities from ISS to missions in the lunar vicinity in preparation for the journey of humans to Mars. As an element of this continued road mapping effort, the ISECG agencies are therefore soliciting input and coordinated discussion with the scientific community to better articulate and promote the scientific opportunities of the proposed mission themes. An improved understanding of the scientific drivers and the requirements to address priority science questions associated with the exploration destinations (Moon, Near Earth Asteroids, Mars and its moons) as well as the preparatory activities in cis-lunar space is beneficial to optimize the partnership of robotic assets and human presence beyond low Earth orbit. The interaction has resulted in the development of a Science White Paper to: • Identify and highlight the scientific opportunities in early exploration missions as the GER reference architecture matures, • Communicate overarching science themes and their relevance in the GER destinations, • Ensure international science communities' perspectives inform the future evolution of mission concepts considered in the GER The paper aims to capture the opportunities offered by the missions in the GER for a broad range of scientific disciplines. These include planetary and space sciences, astrobiology, life sciences, physical sciences, astronomy and Earth science. The paper is structured around grand science themes that draw together and connect research in the various disciplines, and it will focus on opportunities created by the near-term mission themes in the GER centred around 1) extended duration crew missions to an exploration habitat in cis-lunar space, 2) crew mission(s) to an asteroid, and 3) crew missions to the lunar surface. The preparation of that Science White Paper has been coordinated and led by an external Science Advisory Group composed of scientists form a variety of nations. The first draft of this White Paper has been discussed on the occasion of a COSPAR-ISECG-ESF workshop organised in Paris on 10-11 February 2016. The recommendations developed at the workshop provide further input that is incorporated in the final version of the ISECG Science White Paper, expected to be published in the fall of 2016. The authors aim to present the rationale and contents of this White Paper on the occasion of the COSPAR Assembly.

Trends in annual sales and current use of cigarettes, cigars, roll-your-own tobacco, pipes, and smokeless tobacco among US adults, 2002-2012.

PubMed

Agaku, Israel T; Alpert, Hillel R

2016-07-01

Regulatory imbalances exist in the treatment of cigarettes and non-cigarette tobacco products in the USA. We assessed whether declines in cigarette consumption during 2002-2012 were offset by increased use of non-cigarette tobacco products-cigars, pipes, roll-your-own (RYO) and smokeless tobacco. Industry-reported taxable removals (actual sales) were converted into packs for cigarettes and cigarette pack equivalents (CPEs) for loose tobacco (RYO plus pipe tobacco) and moist snuff. Cigars were not converted to CPEs because of their heterogeneity in size/tobacco content. Per capita sales were calculated for the US adult population aged ≥18 years based on the US Census Bureau data. Self-reported data on current (past 30-day) tobacco use among US adults aged ≥18 years were from the National Survey on Drug Use and Health (NSDUH). Joinpoint and logistic regression were used to assess linear trends during 2002-2012. During 2002-2012, cigarette sales declined from 96.91 to 59.85 cigarette packs per capita; increases occurred for sale of cigars (30.51-57.42 cigars per capita), loose tobacco (2.50-5.63 CPEs per capita) and moist snuff (10.64-14.58 CPEs per capita; all p<0.05 for trend). Self-reported current cigarette smoking declined during 2002-2012 (27.4-23.6%); increases were noted for current RYO (2.6-3.6%) and smokeless tobacco use (3.5-3.7%; all p<0.05 for trend). The increase in non-cigarette tobacco consumption is a public health concern because all tobacco products are harmful. Eliminating imbalances in tax structure and regulations between cigarettes and non-cigarette tobacco products may help reduce aggregate tobacco consumption. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Carbon and Nitrogen Input Fluxes in Subducting Sediments at the Izu-Bonin and Central America Convergent Margins

NASA Astrophysics Data System (ADS)

Li, L.; Sadofsky, S. J.; Bebout, G. E.

2003-12-01

We are investigating the N and C contents and isotope ratios in subducting sediment sections in the two MARGINS Subduction Factory focus sites, the Izu-Bonin (IB) and Central America (CA) convergent margins (using samples obtained on DSDP/ODP Legs 125, 170, 185, and 205). The sediments from IB (Site 1149, and Leg 129) contain 5 to 661 ppm N with δ 15NAir values of +2.5 to +8.2 per mil (weighted average +4.6 per mil). Reduced-C concentrations range from 0.02 to 0.35% with δ 13CPDB values from -28.1 to -21.7 per mil. Calcite in carbonate-rich layers has δ 13C of +1.7 to +2.8 per mil and δ 18OVSMOW of +28.5 to +29.7 per mil. In comparison with IB, the CA sediment section (Site 1039) has far higher N content (663 to 2380 ppm N with δ 15N of +3.9 to +7.1 per mil; weighted average +5.6 per mil). Calcite in Site 1039 carbonate-rich layers hasδ 13C of +0.1 to +3.0 per mil and δ 18O of +29.9 to +32.1 per mil. At Site 1149, down-section decrease in N content, accompanied by decrease in δ 15N and C/N, is thought to reflect diagenesis, whereas at Site 1039, down-section decrease in N content (near 2000 ppm at surface, near 1000 ppm at 150 km) occurs without an obvious shift in δ 15N (reduced C data not yet available). Based on the C-N concentration data we've obtained, sediment C-N input fluxes are estimated at, for the IB margin, 2.5x106 g/km.year for N, 1.7x107 g/km.year for reduced C, and 9.2x108 g/km.year for oxidized C. For the CA margin, we estimate input fluxes of 8.9x106 g/km.year for N, and 1.3x109 g/km.year for oxidized C (work on reduced C is underway). Our input fluxes for C and N differ significantly from previously published input fluxes for the two margins based on estimated subducting sediment C-N concentrations, but errors are large. For the CA margin, the sediment-only N input flux of 9.8x109 g/year (for the entire 1100 km trench length), based on our results for Site 1039, can be compared with the arc volcanic output flux of 8.1x109 g/year of Fischer et al. (2002, Science; N input flux of 6.4x109 g/year estimated by those authors), indicating the incomplete return of subducted N to the surface in arcs. The magnitude of the N input flux in altered oceanic crust remains unknown (work on AOC N-δ 15N is underway) but should also be considered in such comparisons. All estimates of this type assume uniformity in the incoming sediment section along-strike in active trenches (known not to be the case). Shifts from δ 15N values measured for the two sediment sections to values near +7 per mil for the deeply subducted sediment component as suggested by studies of volcanic gases (e.g., Fischer et al., 2002; Hilton et al., 2002) could be accomplished by moderate loss of isotopically light N during metamorphic devolatilization across forearcs.

Production of Xylitol from D-Xylose by Overexpression of Xylose Reductase in Osmotolerant Yeast Candida glycerinogenes WL2002-5.

PubMed

Zhang, Cheng; Zong, Hong; Zhuge, Bin; Lu, Xinyao; Fang, Huiying; Zhuge, Jian

2015-07-01

Efficient bioconversion of D-xylose into various biochemicals is critical for the developing lignocelluloses application. In this study, we compared D-xylose utilization in Candida glycerinogenes WL2002-5 transformants expressing xylose reductase (XYL1) in D-xylose metabolism. C. glycerinogenes WL2002-5 expressing XYL1 from Schefferomyces stipitis can produce xylitol. Xylitol production by the recombinant strains was evaluated using a xylitol fermentation medium with glucose as a co-substrate. As glucose was found to be an insufficient co-substrate, various carbon sources were screened for efficient cofactor regeneration, and glycerol was found to be the best co-substrate. The effects of glycerol on the xylitol production rate by a xylose reductase gene (XYL1)-overexpressed mutant of C. glycerinogenes WL2002-5 were investigated. The XYL1-overexpressed mutant produced xylitol from D-xylose using glycerol as a co-substrate for cell growth and NAD (P) H regeneration: 100 g/L D-xylose was completely converted into xylitol when at least 20 g/L glycerol was used as a co-substrate. XYL1 overexpressed mutant grown on glycerol as co-substrate accumulated 2.1-fold increased xylitol concentration over those cells grown on glucose as co-substrate. XYL1 overexpressed mutant produced xylitol with a volumetric productivity of 0.83 g/L/h, and a xylitol yield of 98 % xylose. Recombinant yeast strains obtained in this study are promising candidates for xylitol production. This is the first report of XYL1 gene overexpression of C. glycerinogenes WL2002-5 for enhancing the efficiency of xylitol production.

Miscellaneous lunar tables from Babylon

NASA Astrophysics Data System (ADS)

Steele, J. M.

2006-03-01

In the process of searching through unpublished astronomical material in the cuneiform collection of the British Museum I have identified a number of new tabular astronomical texts of the kind published by O. Neugebauer in Astronomical Cuneiform Texts [1955] (hereafter:ACT). Several lunar tables were published in Steele [2002]. Here I publish another group of lunar ephemerides and related texts identified over the past five years, together with two tablets (BM 36961 and BM 37021) identified and described by A. Aaboe but never published, and two previously unpublished joins to ACT tablets (ACT No. 3a and ACT No. 4a) made by A. Sachs and A. Aaboe.

Comparison of the EIA, EETA and ETWA, received in the model GSM TIP, at the self-consistent approach and with use of the model MSIS-90

NASA Astrophysics Data System (ADS)

Klimenko, M. V.; Klimenko, V. V.; Bryukhanov, V. V.

On the basis of the Global Self-consistent model of the thermosphere ionosphere and protonosphere GSM TIP developed in WD IZMIRAN the calculations for the quiet geomagnetic conditions of the equinox in the minimum of solar activity are carried out In the calculations the new block of the computation of electric fields in the ionosphere briefly described in COSPAR2006-A-00108 was used Two variants of calculations are executed with the account only the dynamo field generated by the thermosphere winds - completely self-consistent and with use of the model MSIS-90 for the calculation of the composition and temperature of the neutral atmosphere The results of the calculations are compared among themselves The global distributions of the foF2 the latitude behavior of the N e and T e on the near-midnight meridian at two height levels 233 and 626 km the latitude-altitude sections on the near-midnight meridian of the T e and time developments on UT of zonal component of the thermosphere wind and ion temperature at height sim 300 km and foF2 and h m F2 for three longitudinal chains of stations - Brazil Pacific and Indian in a vicinity of geomagnetic equator COSPAR2006-A-00109 calculated in two variants are submitted It is shown that at the self-consistent approach the maxima of the crests of the equatorial ionization anomaly EIA in the foF2 are shifted concerning calculated with the MSIS aside later evening hours The equatorial electron temperature anomaly EETA is formed in both variants of calculations However at the

Phobos-Grunt Mission: Planetary Protection Issues and how to Solve Them (the Approaches Based on the Exobiological Experiments Results)

NASA Astrophysics Data System (ADS)

Novikova, Nataliya; Orlov, Oleg; Deshevaya, Elena; Sychev, Vladimir; Khamidullina, N.; Aleksashkin, Sergey; Martynov, Maxim

The launch of a Russian spaceship to Phobos is being planned in 2011 as a part of the project "Phobos-Soil". Major goals of the mission are: -Landing of the orbital vehicle (transport module) on the Phobos surface, collecting soil samples for delivery to Earth in a sealed inde-structible container; -Some experiments, including exobiological experiment aimed to evaluate viability of dormant organisms-representatives of a variety of taxonomic groups after extended interplanetary trip. According to COSPAR classification the orbital Mars spaceship flight is related to the category III and the mission of Phobos soil delivery to the Earth in a capsule on a descent vehicle is related to the category V to which any missions of return to the Earth are related. In order to supply Mars and Earth protection a number of actions is worked out: -The probability of space craft destruction and its falling down on the Mars surface is limited, and that is proved by the calculations; -The proposals to break the "chain of contact" with Earth of equipment used on the Phobos surface; -Preservation of tightness of the containers with Phobos soil and biological samples should be provided at all the stages of the mission up to the landing onto the Earth; -Phobos soil and biological samples delivery to specialized organiza-tion licensed to carry out works with highly dangerous microorganisms should be organized. So severe measures of the planet protection are based not only on the COSPAR demands, but also on the results of the Russian exobiological experiments, which proved that ability of survival in outer space was shown experimentally not only for spores of bacteria and microscopic fungi, but also for resting stages of higher organisms.

Ethical Considerations for Planetary Protection in Space Exploration: A Workshop

PubMed Central

Rummel, J.D.; Horneck, G.

2012-01-01

Abstract With the recognition of an increasing potential for discovery of extraterrestrial life, a diverse set of researchers have noted a need to examine the foundational ethical principles that should frame our collective space activities as we explore outer space. A COSPAR Workshop on Ethical Considerations for Planetary Protection in Space Exploration was convened at Princeton University on June 8–10, 2010, to examine whether planetary protection measures and practices should be extended to protect planetary environments within an ethical framework that goes beyond “science protection” per se. The workshop had been in development prior to a 2006 NRC report on preventing the forward contamination of Mars, although it responded directly to one of the recommendations of that report and to several peer-reviewed papers as well. The workshop focused on the implications and responsibilities engendered when exploring outer space while avoiding harmful impacts on planetary bodies. Over 3 days, workshop participants developed a set of recommendations addressing the need for a revised policy framework to address “harmful contamination” beyond biological contamination, noting that it is important to maintain the current COSPAR planetary protection policy for scientific exploration and activities. The attendees agreed that there is need for further study of the ethical considerations used on Earth and the examination of management options and governmental mechanisms useful for establishing an environmental stewardship framework that incorporates both scientific input and enforcement. Scientists need to undertake public dialogue to communicate widely about these future policy deliberations and to ensure public involvement in decision making. A number of incremental steps have been taken since the workshop to implement some of these recommendations. Key Words: Planetary protection—Extraterrestrial life—Life in extreme environments—Environment—Habitability. Astrobiology 12, 1017–1023. PMID:23095097

Four Fallacies and an Oversight: Searching for Martian Life

NASA Astrophysics Data System (ADS)

Rummel, J. D.; Conley, C. A.

2017-10-01

While it is anticipated that future human missions to Mars will increase the amount of biological and organic contamination that might be distributed on that planet, robotic missions continue to grow in capability and complexity, requiring precautions to be taken now to protect Mars, and particularly areas of Mars that might be Special Regions. Such precautionary cleanliness requirements for spacecraft have evolved over the course of the space age, as we have learned more about planetary environments, and are the subject of regular deliberations and decisions sponsored by the Committee on Space Research (COSPAR). COSPAR's planetary protection policy is maintained as an international consensus standard for spacecraft cleanliness that is recognized by the United Nations Committee on the Peaceful Uses of Outer Space. In response to the paper presented in this issue by Fairén et al. (2017), we examine both their concept of evidence for possible life on Mars and their logic in recommending that spacecraft cleanliness requirements be relaxed to access Special Regions "before it is too late." We find that there are shortcomings in their plans to look for evidence of life on Mars, that they do not support their contention that appropriate levels of spacecraft cleanliness are unaffordable, that there are major risks in assuming martian life could be identified by nucleic acid sequence comparison (especially if those sequences are obtained from a Special Region contaminated with Earth life), and that the authors do not justify their contention that exploration with dirty robots, now, is preferable to the possibility that later contamination will be spread by human exploration. We also note that the potential effects of contaminating resources and environments essential to future human occupants of Mars are both significant and not addressed by Fairén et al. (2017).

[Scientists in cartoons: humanizing science].

PubMed

Fioravanti, Carlos Henrique; Andrade, Rodrigo de Oliveira; Marques, Ivan da Costa

2016-01-01

Published daily from 1994 to 2002 in Correio Popular, a Campinas-based newspaper, Os cientistas (The scientists) comic strips produced by Brazilian researchers and journalists presented science critically and irreverently, exposing the insecurities and frustrations of scientists, as well as the conflicts between them and their communication difficulties with other groups, like journalists. This article shows the diversity of personalities, subjects, graphic styles, and potential meanings in a sample of comic strips published in the first four years.

Recommendations on the diagnosis, treatment and monitoring of late-onset hypogonadism in men - a suggested update.

PubMed

Lunenfeld, Bruno; Mskhalaya, George; Kalinchenko, Svetlana; Tishova, Yulia

2013-12-01

Recommendations on the diagnosis, treatment and monitoring of late-onset hypogonadism (LOH) in men were first published by ISSAM in 2002 In 2005, and, in 2008, updated recommendations were published in the International Journal of Andrology, the Journal of Andrology, the Aging Male and European Urology. Towards discussions at the next ISSAM/ESSAM meeting in Moscow, 29 November 2013, we suggest the following update.

Empirical Agility

DTIC Science & Technology

2014-06-01

in World War II. One of its most effective applications is recorded in a very interesting little book entitled Patton’s Air Force ( Spires , 2002...Publishing Company, Amsterdam. 1973. Spires , David N, Patton’s Air Force: Forging a Legendary Air-Ground Team. Smithsonian Institution Press, Washington

Towards a Framework for Understanding Innovation Implementation in the Air Force

DTIC Science & Technology

2003-03-25

177 (Feb 2002). Hall, G. E., R. C. Wallace and W. A. Dossett. A Developmental Conceptualization of the Adoption Process within Educational...3. DATES COVERED (From – To) Jun 2002 – Jan 2003 5a. CONTRACT NUMBER 5b. GRANT NUMBER 4. TITLE AND SUBTITLE TOWARDS A FRAMWORK FOR

77 FR 20281 - Designation of Product Categories for Federal Procurement

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-04

... Security and Rural Investment Act of 2002, as amended by the Food, Conservation, and Energy Act of 2008.... Information regarding the Federal biobased preferred procurement program (one part of the BioPreferred Program... of 2002 (FSRIA), as amended by the Food, Conservation, and Energy Act of 2008 (FCEA), 7 U.S.C. 8102...

On broadening the cognitive, motivational, and sociostructural scope of theorizing about gender development and functioning: comment on Martin, Ruble, and Szkrybalo (2002).

PubMed

Bandura, Albert; Bussey, Kay

2004-09-01

In their article on gender development, C. L. Martin, D. N. Ruble, and J. Szkrybalo (see record 2002-18663-003) contrasted their conception of gender development with that of social cognitive theory. The authors of this commentary correct misrepresentations of social cognitive theory and analyze the conceptual and empirical status of Martin et al.'s (2002) theory that gender stereotype matching is the main motivating force of gender development. Martin et al. (2002) based their claim for the causal primacy of gender self-categorization on construal of gender discrimination as rudimentary self-identity, equivocal empirical evidence, and dismissal of discordant evidence because of methodological deficiencies. The repeated finding that gendered preferences and behavior precede emergence of a sense of self is discordant with their theory. Different lines of evidence confirm that gender development and functioning are socially situated, richly contextualized, and conditionally manifested rather than governed mainly by an intrinsic drive to match stereotypic gender self-conception. ((c) 2004 APA, all rights reserved)

Brazilian Coffee Production as Function of Global Warming.

NASA Astrophysics Data System (ADS)

Avila, A. M. H. D.; Pinto, H. S.; Alfonsi, E. L., Sr.; Alfonsi, W. M. V.; Pereira, V. R.

2016-12-01

According to the Brazilian Government the actual area of coffee production in the country is close to 2.25 million hectares. The sector involves 290.000 of farmers with a production of 44 million of 60 Kg bags in 2015. The Arabica Coffee specie is cultivated in the country where the climate condition are characterized by a year mean temperatures between 18°C and 22°C. Temperatures higher than 33°C can cause abortion of flowers during the spring season and reduce the production while lower than 18°C can be affected by frost during winter when the minimum temperature can be lower than 2°C in the shelter. For a better quality of the final product the winter, between July and August, must be dry with rainfall lower than 50 mm/month. The Ministry of Agriculture defines those conditions for the Official Coffee Climatic Risk Zoning. In 2002, a partnership with the British Embassy and 2 Brazilian institutions, i. e. the State University of Campinas - UNICAMP and the Brazilian Agricultural Research Corporation - Embrapa, published the study "Global Warming and the New Geography of Agricultural Production in Brazil" (Pinto and Assad, 2002). This study was based on the PRECIS/Hadley Centre Regional Climate Model future projections. The crop simulations indicated a decrease in the grain production due to temperature rise. Later in 2012, a new study was developed in cooperation with the World Bank to evaluate the future of nine main commodities in Brazil under climate change, including the Arabica coffee. The worst scenario considering any mitigation and adaptation action indicated that the two most affected crops would be the soybean and coffee, with a reduction of 22% and 6.7 % in the yield respectively. Field surveys to evaluate the historical spatial dynamic and migration of Arabica coffee cultivated areas confirmed the results of the previous studies and indicated a recent increase in the search for cooler altitude areas to plant coffee. Also the field observations showed an increase in Robusta, a specie less susceptible to heat, in areas previously occupied with Arabica.

A decade of temporal trends in overweight/obesity in youth with type 1 diabetes after the Diabetes Control and Complications Trial.

PubMed

Baskaran, Charumathi; Volkening, Lisa K; Diaz, Monica; Laffel, Lori M

2015-06-01

Youth with type 1 diabetes (T1D) are at risk for weight gain due to the epidemic of childhood overweight/obesity and common use of intensive insulin therapy; the latter resulted in weight gain in the Diabetes Control and Complications Trial. To assess overweight/obesity prevalence and intensive insulin therapy use in youth with T1D over a decade and identify factors associated with weight status and glycemic control. We obtained cross-sectional data from four unique cohorts (1999, 2002, 2006, and 2009). Youth (N = 507, 49% male) were 8-16 yr old with T1D duration ≥6 months, A1c 6.0-12.0% (42-108 mmol/mol), and daily insulin dose ≥0.5 U/kg. Across cohorts, age, body mass index (BMI) percentile, and A1c ranged from 12.0 ± 2.2 to 12.8 ± 2.3 yr, 70 ± 22 to 72 ± 21, and 8.3 ± 1.0 (67 ± 11) to 8.5 ± 1.1% (69 ± 12 mmol/mol), respectively. Intensive insulin therapy use increased from 52 to 97% (p < 0.001) between 1999 and 2009. However, prevalence of overweight/obesity remained similar, 27% (1999), 36% (2002), 33% (2006), and 31% (2009) (p = 0.54), as did z-BMI. In multivariate analysis, higher A1c was related to higher insulin dose (p < 0.01), less frequent blood glucose monitoring (p < 0.001), and non-white race (p < 0.001); A1c was not related to z-BMI, intensive insulin therapy, or cohort. z-BMI was related to insulin dose (p < 0.005) but not intensive insulin therapy or cohort. Despite near-universal implementation of intensive insulin therapy, overweight/obesity prevalence in youth with T1D remained stable over a decade, similar to the general pediatric population. However, A1c remained suboptimal, underscoring the need to optimize T1D treatment to reduce future complication risk. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

[Not Available].

PubMed

Abril, Encarnación; Gómez-Conesa, Antonia; Gutiérrez-Santos, Manuel

2008-05-01

To assess the quality of physiotherapeutic care in patients treated for low back pain in a Primary Health Care physiotherapy unit, and to improve the quality of the care provided to these patients. The first assessment includes all patients treated in 2002 (n=83). Five criteria corresponding to the initial physiotherapeutic assessment were chosen: C1, pain; C2, disability; C3, mobility, muscle examination, and C5, palpation. In order to detect non-compliance, the Ishikawa Fishbone diagram was used. Corrective measures were established in November 2003: publication of an Oswestry questionnaire model for assessing disability and reflecting on the results obtained. The second assessment includes the period of time from 1st November 2003 to 6th April 2004 (n=32). In the initial assessment, compliances observed were: C1: 21.69%; C2: 0; C3: 69.87%; C4: 78.31%, and C5: 84.33%. After implementing corrective measures a significant improvement was observed in the compliance of C1, C2, and C3. In C4 there was an improvement, and in C5 there was a decrease in compliance, both of them without statistical significance. The carrying out of an improvement cycle has enabled non-compliances in the application of this protocol to be detected and corrected. The corrective measures implemented have led to a reduction of the variability in the records. It is advisable to ensure that compliance does not decrease in the areas that initially showed a high level of compliance. Copyright © 2008 Sociedad Española de Calidad Asistencial. Published by Elsevier Espana. All rights reserved.

10 Year Publication Trends in Dermatology in Mainland China

PubMed Central

Xin, Shujun; Mauro, Jacqueline A; Mauro, Theodora M; Elias, Peter M; Man, Mao-Qiang

2013-01-01

Background China has been experiencing huge changes in all aspects including dermatologic research since its reform in 1978. However, how the economic and intellectual development has influenced the publication trends in the field of dermatology, which could mirror the scientific development in other medical disciplines, is unknown. In the present study, we analyzed the publication trends from departments of dermatology in mainland China from 2002 to 2011. Materials and Methods All publication data were obtained from www.pubmed.com. Only papers published from dermatology departments of mainland China were used for analysis. Results The number of publications increased 10-fold over this 10 year period. A total 1,231 of articles were published in English in 251 journals between 2002 and 2011. A total of 129 journals published only one paper from dermatology departments of mainland China. Over 60% of articles were original research and 21.7% were case reports. Among these 251 journals, foremost was the Journal of Clinical Experimental Dermatology, which published 5.9% of all papers from mainland China. 2.7% papers were published in the Journal of Investigative Dermatology. The number of publications positively correlated with the changes in gross domestic product per capita during the study period. Conclusions These results suggest that the number of publications in the dermatology field has increased markedly in mainland China over the last 10 years. This dramatic increase in publications could be, at least partially, attributed to the significant improvement in economic conditions in mainland China. PMID:23968296

Ten-year publication trends in dermatology in mainland China.

PubMed

Xin, Shujun; Mauro, Jacqueline A; Mauro, Theodora M; Elias, Peter M; Man, Mao-Qiang

2014-10-01

China has been experiencing huge changes in all aspects, including dermatologic research, since its reform in 1978. However, it is not known how the economic and intellectual development has influenced the publication trends in the field of dermatology, which could mirror the scientific development in other medical disciplines. In the present study, we analyzed publication trends from dermatology departments in mainland China from 2002 to 2011. All publication data were obtained from www.pubmed.com. Only papers published from dermatology departments in mainland China were used for analysis. The number of publications increased 10-fold over this 10-year period. A total of 1231 articles were published in English in 251 journals between 2002 and 2011. A total of 129 journals published only one paper from dermatology departments in mainland China. Over 60% of articles were original research, and 21.7% were case reports. Among these 251 journals, foremost was the Journal of Clinical Experimental Dermatology, which published 5.9% of all papers from mainland China; 2.7% of papers were published in the Journal of Investigative Dermatology. The number of publications positively correlated with the changes in gross domestic product per capita during the study period. These results suggest that the number of publications in the dermatology field has increased markedly in mainland China over the last 10 years. This dramatic increase in publications could be attributed, at least partially, to the significant improvement in economic conditions in mainland China. © 2013 The International Society of Dermatology.

Non-Methane Hydrocarbon Measurements Aboard the NOAA Research Vessel Ronald H. Brown during the 2002 New England Air Quality Study (NEAQS 2002)

NASA Astrophysics Data System (ADS)

Goldan, P. D.; Kuster, W. C.; Williams, E.; Fehsenfeld, F. C.

2003-12-01

During the NEAQS 2002 study, in-situ NMHC measurements were made aboard the NOAA research vessel Ronald H. Brown by a two channel automated gas chromatograph using both flame ionization and mass-spectrometric detection techniques. Five minute average samples were cryogenically trapped each 1/2 hour and analyzed immediately for C2 through C10 alkanes, C2 through C5 alkenes, C6 through C9 aromatics, C2 through C8 aldehydes and ketones, C1 through C5 alcohols and a variety of compounds of biogenic origin including 6 monoterpenes, isoprene and its primary oxidation products methacrolein and methylvinyl ketone. The relative contributions of these classes of compounds to OH photochemistry has been determined for air masses ranging from those showing significant anthropogenic influence to clean marine air. For the most anthropogenically influenced air masses, alkenes were observed to play a dominant role whereas oxy-hydrocarbons, principally acetaldehyde, were observed to dominate under clean marine conditions. Both the NMHC measurements and back trajectory analyses indicated periods of significant influx into the New England coastal region of urban air masses showing elevated ozone levels from the Boston/Providence urban corridor. About as frequently, less photochemically mature air masses, depleted in ozone but laden with light reactive alkenes, were observed coming from the Portsmouth NH/Kittery ME coastal urban complex. Even in the presence of these anthropogenic plumes, biogenic hydrocarbons appear to dominate OH photochemistry in the New England region much of the time. Data demonstrating all of these conclusions will be shown.

Observations of Distant Clusters

NASA Technical Reports Server (NTRS)

Donahue, Megan

2004-01-01

The is the proceedings and papers supported by the LTSA grant: Homer, D. J.\\& Donahue, M. 2003, in "The Emergence of Cosmic Structure": 13'h Astrophysics Conference Proceedings, Vol. 666,3 1 1-3 14, (AIP). Baumgartner, W. H., Loewenstein, M., Horner, D. J., Mushotzky, R. F. 2003, HEAD- AAS, 35.3503. Homer, D. J. , Donahue, M., Voit G. M. 2003, HEAD-AAS, 35.1309. Nowak, M. A., Smith, B., Donahue, M., Stocke, J. 2003, HEAD-AAS, 35.1316. Scott, D., Borys, C., Chapman, S. C., Donahue, M., Fahlman, G. G., Halpem, M. Newbury, P. 2002, AAS, 128.01. Jones, L. R. et al. 2002, A new era in cosmology, ASP Conference Proceedings, Vol. 283, p. 223 Donahue, M., Daly, R. A., Homer, D. J. 2003, ApJ, 584, 643, Constraints on the Cluster Environments and Hotspot magnetic field strengths for radio sources 3280 and 3254. Donahue, M., et al. 2003, ApJ, 598, 190. The mass, baryonic fraction, and x-ray temperature of the luminous, high-redshift cluster of galaxies MS045 1.6-0305 Perlman, E. S. et al. 2002, ApJS, 140, 256. Smith, B. J., Nowak, M., Donahue, M., Stocke, J. 2003, AJ, 126, 1763. Chandra Observations of the Interacting NGC44 10 Group of Galaxies. Postman, M., Lauer, T. R., Oegerle, W., Donahue, M. 2002, ApJ, 579, 93. The KPNO/deep-range cluster survey I. The catalog and space density of intermediate-redshift clusters. Molnar, S. M., Hughes, J. P., Donahue, M., Joy, M. 2002, ApJ, 573, L91, Chandra Observations of Unresolved X-Ray Sources around Two Clusters of Galaxies. Donahue, M., Mack, J., 2002 NewAR, 46, 155, HST NIcmos and WFPC2 observations of molecular hydrogen and dust around cooling flows. Koekemoer, A. M. et al. 2002 NewAR, 46, 149, Interactions between the A2597 central radio source and dense gas host galaxy. Donahue, M. et al. 2002 ApJ, 569,689, Distant cluster hunting II.

Genome sequence of a microbial lipid producing fungus Cryptococcus albidus NT2002.

PubMed

Yong, Xiaoyu; Yan, Zhiying; Xu, Lin; Zhou, Jun; Wu, Xiayuan; Wu, Yuandong; Li, Yang; Chen, Zugeng; Zhou, Hua; Wei, Ping; Jia, Honghua

2016-04-10

Cryptococcus albidus NT2002, isolated from the soil in Xinjiang, China, appeared to have the ability to accumulate microbial lipid by utilizing various carbon sources. The predominant properties make it as a potential bio-platform for biodiesel production. Here, we report the complete genome sequence of C. albidus NT2002, which might provide a basis for further elucidation of the genetic background of this promising strain for developing metabolic engineering strategies to produce biodiesel in a green and sustainable manner. Copyright © 2016 Elsevier B.V. All rights reserved.

Number and Impact of Published Scholarly Works by Pharmacy Practice Faculty Members at Accredited US Colleges and Schools of Pharmacy (2001-2003)

PubMed Central

Coleman, Craig I.; Schlesselman, Lauren S.; Lao, Eang

2007-01-01

Objective To evaluate the quantity and quality of published literature conducted by pharmacy practice faculty members in US colleges and schools of pharmacy for the years 2001-2003. Methods The Web of Science bibliographic database was used to identify publication citations for the years 2001-2003, which were then evaluated in a number of different ways. Faculty members were identified using American Association of Colleges of Pharmacy rosters for the 2000-2001, 2001-2002, and 2002-2003 academic years. Results Two thousand three hundred seventy-four pharmacy practice faculty members generated 1,896 publications in Web of Science searchable journals. A small number of faculty members (2.1%) were responsible for a large proportion of publications (30.6%), and only 4.9% of faculty members published 2 or more publications in these journals per year. The average impact factor for the top 200 publications was 7.6. Conclusion Pharmacy practice faculty members contributed substantially to the biomedical literature and their work has had an important impact. A substantial portion of this work has come from a small subset of faculty members. PMID:17619644

Estimated anthropogenic nitrogen and phosphorus inputs to the land surface of the conterminous United States--1992, 1997, and 2002

USGS Publications Warehouse

Sprague, Lori A.; Gronberg, Jo Ann M.

2013-01-01

Anthropogenic inputs of nitrogen and phosphorus to each county in the conterminous United States and to the watersheds of 495 surface-water sites studied as part of the U.S. Geological Survey National Water-Quality Assessment Program were quantified for the years 1992, 1997, and 2002. Estimates of inputs of nitrogen and phosphorus from biological fixation by crops (for nitrogen only), human consumption, crop production for human consumption, animal production for human consumption, animal consumption, and crop production for animal consumption for each county are provided in a tabular dataset. These county-level estimates were allocated to the watersheds of the surface-water sites to estimate watershed-level inputs from the same sources; these estimates also are provided in a tabular dataset, together with calculated estimates of net import of food and net import of feed and previously published estimates of inputs from atmospheric deposition, fertilizer, and recoverable manure. The previously published inputs are provided for each watershed so that final estimates of total anthropogenic nutrient inputs could be calculated. Estimates of total anthropogenic inputs are presented together with previously published estimates of riverine loads of total nitrogen and total phosphorus for reference.

Medical and biomedical research productivity from Palestine, 2002 - 2011.

PubMed

Sweileh, Waleed M; Zyoud, Sa'ed H; Sawalha, Ansam F; Abu-Taha, Adham; Hussein, Ayman; Al-Jabi, Samah W

2013-02-02

Medical research productivity reflects the level of medical education and practice in a particular country. The objective of this study was to examine the quantity and quality of medical and biomedical research published from Palestine. Comprehensive review of the literature indexed by Scopus was conducted. Data from Jan 01, 2002 till December 31, 2011 was searched for authors affiliated with Palestine or Palestinian authority. Results were refined to limit the search to medical and biomedical subjects. The quality of publication was assessed using Journal Citation Report. The total number of publications was 2207. A total of 770 publications were in the medical and biomedical subject areas. The annual rate of publication was 0.077 articles per gross domestic product/capita. The 770 publications have an h-index of 32. One hundred and thirty eight (18%) articles were published in 46 journals that were not indexed in the web of knowledge. Twenty two (22/770; 2.9%) articles were published in journals with an IF > 10. The quantity and quality of research originating from Palestinian institutions is promising given the scarce resources of Palestine. However, more effort is needed to bridge the gap in medical research productivity and to promote better health in Palestine.

Temperature Management After Cardiac Arrest: An Advisory Statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation.

PubMed

Donnino, Michael W; Andersen, Lars W; Berg, Katherine M; Reynolds, Joshua C; Nolan, Jerry P; Morley, Peter T; Lang, Eddy; Cocchi, Michael N; Xanthos, Theodoros; Callaway, Clifton W; Soar, Jasmeet

2016-01-01

For more than a decade, mild induced hypothermia (32 °C-34 °C) has been standard of care for patients remaining comatose after resuscitation from out-of-hospital cardiac arrest with an initial shockable rhythm, and this has been extrapolated to survivors of cardiac arrest with initially nonshockable rhythms and to patients with in-hospital cardiac arrest. Two randomized trials published in 2002 reported a survival and neurological benefit with mild induced hypothermia. One recent randomized trial reported similar outcomes in patients treated with targeted temperature management at either 33 °C or 36 °C. In response to these new data, the International Liaison Committee on Resuscitation Advanced Life Support Task Force performed a systematic review to evaluate 3 key questions: (1) Should mild induced hypothermia (or some form of targeted temperature management) be used in comatose post-cardiac arrest patients? (2) If used, what is the ideal timing of the intervention? (3) If used, what is the ideal duration of the intervention? The task force used Grading of Recommendations Assessment, Development and Evaluation methodology to assess and summarize the evidence and to provide a consensus on science statement and treatment recommendations. The task force recommends targeted temperature management for adults with out-of-hospital cardiac arrest with an initial shockable rhythm at a constant temperature between 32 °C and 36 °C for at least 24 hours. Similar suggestions are made for out-of-hospital cardiac arrest with a nonshockable rhythm and in-hospital cardiac arrest. The task force recommends against prehospital cooling with rapid infusion of large volumes of cold intravenous fluid. Additional and specific recommendations are provided in the document. Copyright © 2015. Published by Elsevier Ireland Ltd.