Pilot Fullerton reviews FDF and TAGS printout on forward flight deck

NASA Technical Reports Server (NTRS)

1982-01-01

Pilot Fullerton, wearing communications kit assembly (ASSY) mini headset (HDST), reviews flight data file (FDF) checklist and text and graphics system (TAGS) printout (ticker tape) while in pilots ejection seat (S2). Pilot Station control panels F4, F7, F8, O3, window shade, and portable oxygen system (POS) assy appear in view.

Pilot Fullerton examines SE-81-8 Insect Flight Motion Study

NASA Image and Video Library

1982-03-30

STS003-23-178 (22-30 March 1982) --- Astronaut C. Gordon Fullerton, STS-3 pilot, examines Student Experiment 81-8 (SE-81-8) Insect Flight Motion Study taped to the airlock on aft middeck. Todd Nelson, a high school senior from Minnesota, won a national contest to fly his experiment on this particular flight. Moths, flies, and bees were studied in the near weightless environment. Photo credit: NASA

Pilot Fullerton points Hasselblad camera out forward flight deck window W6

NASA Technical Reports Server (NTRS)

1982-01-01

Pilot Fullerton, wearing communications kit assembly (ASSY) mini headset (HDST), points Hasselblad camera out forward flight deck pilots station window W6. Forward flight deck control panels F4, F8, and R1, flight mirror assy, Volume R5 Kit, and pilots ejection seat (S2) headrest appear in view.

An Analysis of the Requirements and Potential Opportunities for the Future Education of Law Enforcement Intelligence Analysts

DTIC Science & Technology

2008-03-01

thinking as a specialized course. None of these schools requires a foreign language. Only Cal State Fullerton and Sacrament State requires students to...research methods. None of the schools require a foreign language. AMU offers critical thinking as an elective from its General Program for students ...analysts should learn more about the religion. Question Six: Instruction in which of these types of philosophies (Western, Eastern, Middle Eastern, or

Pilot Fullerton reviews FDF and TAGS printout on forward flight deck

NASA Image and Video Library

1982-03-30

STS003-23-180 (22-30 March 1982) --- Astronaut Gordon Fullerton, STS-3 pilot, wearing communications kit assembly (ASSY) mini-headset (HDST), reviews flight data file (FDF) checklist and text and graphics system (TAGS) printout (ticker tape) while in pilots ejection seat (S2). Pilot station control panels F4, F7, F8, O3, window shade, and portable oxygen system (POS) assy appear in view. Photo credit: NASA

Pilot Fullerton in ejection escape suit (EES) on aft flight deck

NASA Image and Video Library

1982-03-30

STS003-31-290 (30 March 1982) --- Astronaut Gordon Fullerton, STS-3 pilot, wearing communications kit assembly (ASSY) mini-headset (HDST) and ejection escape suit (EES), holds flexible hose attached to his EES vent hose fitting and second hose for commander's EES while behind pilots ejection seat (S2) seat back on the aft flight deck. Forward flight deck control panels are visible in the background. Photo credit: NASA

Gordon Fullerton in PCA (MD-11) Simulator

NASA Technical Reports Server (NTRS)

1998-01-01

NASA research pilot Gordon Fullerton 'flying' in the MD-11 simulator during the Propulsion Controlled Aircraft (PCA) project. This investigation grew out of the crash of a DC-10 airliner on July 19, 1989, following an explosion in the rear engine which caused the loss of all manual flight controls. The flight crew attempted to control the airliner using only the thrust from the two remaining engines. Although the DC-10 crashed during the landing attempt, 184 of the 296 passengers and crew aboard survived. The PCA effort at the Dryden Flight Research Center grew out of the crash, and attempted to develop a means to successfully land an aircraft using only engine thrust. After more than five years of work, on August 29, 1995, Gordon Fullerton made the first PCA touchdown aboard an MD-11 airliner (a later version of the DC-10). The concept was further refined over the years that followed this first landing. Simulators were essential ingredients of the PCA development process. The feasibility of the concept was first tested with an F-15 simulator, then the results of actual flight tests in an F-15 were incorporated back into the simulator. Additional simulations were run on the Boeing 720 airliner simulator used in the Controlled Impact Demonstration project. After the MD-11 test landings, Boeing 747 and 757 simulators tested a wide range of possible situations. Simulations even helped develop a method of landing an airliner if it lost its complete hydraulic system as well as a wing engine, by transferring fuel to shift the center of gravity toward the working engine. The most extreme procedure was undertaken in a 747 simulator. The aircraft simulated the loss of the hydraulic system at 35,000 feet and rolled upside down. Then, the PCA mode was engaged, the airliner righted itself, leveled its wings, and made an approach nearly identical to that of a normal auto landing.

Developmental evolution of flowering plant pollen tube cell walls: callose synthase (CalS) gene expression patterns

PubMed Central

2011-01-01

Background A number of innovations underlie the origin of rapid reproductive cycles in angiosperms. A critical early step involved the modification of an ancestrally short and slow-growing pollen tube for faster and longer distance transport of sperm to egg. Associated with this shift are the predominantly callose (1,3-β-glucan) walls and septae (callose plugs) of angiosperm pollen tubes. Callose synthesis is mediated by callose synthase (CalS). Of 12 CalS gene family members in Arabidopsis, only one (CalS5) has been directly linked to pollen tube callose. CalS5 orthologues are present in several monocot and eudicot genomes, but little is known about the evolutionary origin of CalS5 or what its ancestral function may have been. Results We investigated expression of CalS in pollen and pollen tubes of selected non-flowering seed plants (gymnosperms) and angiosperms within lineages that diverged below the monocot/eudicot node. First, we determined the nearly full length coding sequence of a CalS5 orthologue from Cabomba caroliniana (CcCalS5) (Nymphaeales). Semi-quantitative RT-PCR demonstrated low CcCalS5 expression within several vegetative tissues, but strong expression in mature pollen. CalS transcripts were detected in pollen tubes of several species within Nymphaeales and Austrobaileyales, and comparative analyses with a phylogenetically diverse group of sequenced genomes indicated homology to CalS5. We also report in silico evidence of a putative CalS5 orthologue from Amborella. Among gymnosperms, CalS5 transcripts were recovered from germinating pollen of Gnetum and Ginkgo, but a novel CalS paralog was instead amplified from germinating pollen of Pinus taeda. Conclusion The finding that CalS5 is the predominant callose synthase in pollen tubes of both early-diverging and model system angiosperms is an indicator of the homology of their novel callosic pollen tube walls and callose plugs. The data suggest that CalS5 had transient expression and pollen

Cal-Bridge and CAMPARE: Engaging Underrepresented Students in Physics and Astronomy

NASA Astrophysics Data System (ADS)

Rudolph, Alexander L.; Cal-Bridge and CAMPARE Teams

2018-01-01

We describe two programs, Cal-Bridge and CAMPARE, with the common mission of increasing participation of groups traditionally underrepresented in astronomy, through summer research opportunities, in the case of CAMPARE, scholarships in the case of Cal-Bridge, and significant mentoring in both programs, creating a national impact on their numbers successfully pursuing a PhD in the field.In 8 years, the CAMPARE program has sent 112 students, >80% from underrepresented groups, to conduct summer research at one of 14 major research institutions throughout the country. Of the CAMPARE scholars who have graduated with a Bachelor’s degree, almost two-thirds (65%) have completed or are pursuing graduate education in physics, astronomy, or a related field, at institutions including UCLA, UC Riverside, UC Irvine, UC Santa Barbara, USC, Stanford, Univ. of Arizona, Univ. of Washington, Univ. of Rochester, Michigan State Univ., Georgia Tech, Georgia State Univ., Kent State, Indiana Univ., Univ. of Oregon, Syracuse Univ., Montana State Univ., and the Fisk-Vanderbilt Master’s-to-PhD program.Now entering its fourth year, the Cal-Bridge program is a CSU-UC Bridge program comprised of >140 physics and astronomy faculty from 9 University of California (UC), 15 California State University (CSU), and 30 California Community College (CCC) campuses throughout California. In the first four years, 34 Cal-Bridge Scholars have been selected, including 22 Hispanic, 3 African-American and 13 women students, 10 of whom are from URM groups. Thirty (30) of the 34 Cal-Bridge Scholars are first generation college students. In the last two years, 11 of 13 Cal-Bridge Scholars have begun PhD programs in physics or astronomy at top PhD programs nationally. Three (3) of these 11 scholars have won NSF Graduate Research Fellowships; one more received an Honorable Mention. The next cohort applies this fall.Cal-Bridge provides much deeper mentoring and professional development experiences over the last

Cal-Bridge and CAMPARE: Engaging Underrepresented Students in Physics and Astronomy

NASA Astrophysics Data System (ADS)

Rudolph, Alexander L.; Smecker-Hane, Tammy A.; Cal-Bridge Team; CAMPARE Team

2018-06-01

We describe two programs, Cal-Bridge and CAMPARE, with the common mission of increasing participation of groups traditionally underrepresented in astronomy, through summer research opportunities, in the case of CAMPARE, scholarships in the case of Cal-Bridge, and significant mentoring in both programs, creating a national impact on their numbers successfully pursuing a PhD in the field. In 9 years, the CAMPARE program has sent 150 students, >80% from underrepresented groups, to conduct summer research at one of 14 major research institutions throughout the country. Of the CAMPARE scholars who have graduated with a Bachelor’s degree, almost two-thirds (65%) have completed or are pursuing graduate education in physics, astronomy, or a related field, at institutions including UCLA, UC Riverside, UC Irvine, UC Santa Barbara, USC, Stanford, Univ. of Arizona, Univ. of Washington, Univ. of Rochester, Michigan State Univ., Georgia Tech, Georgia State Univ., Kent State, Indiana Univ., Univ. of Oregon, Syracuse Univ., Montana State Univ., and the Fisk- Vanderbilt Master’s-to-PhD program. Now in its fourth year, the Cal-Bridge program is a CSU-UC Bridge program comprised of physics and astronomy faculty from 9 University of California (UC), 15 California State University (CSU), and more than 30 California Community College (CCC) campuses throughout California. In the first four years, 34 Cal-Bridge Scholars have been selected, including 22 Hispanic, 3 African-American and 13 women students, 10 of whom are from URM groups. Thirty (30) of the 34 Cal-Bridge Scholars are first generation college students. In the last three years, 17 of 21 Cal-Bridge Scholars have begun or been accepted PhD programs in physics or astronomy at top PhD programs nationally. Three (3) of these scholars have won NSF Graduate Research Fellowships; one more received an Honorable Mention. Once selected, Cal-Bridge Scholars benefit from substantial financial support, intensive, joint mentoring by CSU

Retired NASA research pilot and former astronaut Gordon Fullerton was greeted by scores of NASA Dryden staff who bid him farewell after his final NASA flight.

NASA Image and Video Library

2007-12-21

Long-time NASA Dryden research pilot and former astronaut C. Gordon Fullerton capped an almost 50-year flying career, including more than 38 years with NASA, with a final flight in a NASA F/A-18 on Dec. 21, 2007. Fullerton and Dryden research pilot Jim Smolka flew a 90-minute pilot proficiency formation aerobatics flight with another Dryden F/A-18 and a Dryden T-38 before concluding with two low-level formation flyovers of Dryden before landing. Fullerton was honored with a water-cannon spray arch provided by two fire trucks from the Edwards Air Force Base fire department as he taxied the F/A-18 up to the Dryden ramp, and was then greeted by his wife Marie and several hundred Dryden staff after his final flight. Fullerton began his flying career with the U.S. Air Force in 1958 after earning bachelor's and master's degrees in mechanical engineering from the California Institute of Technology. Initially trained as a fighter pilot, he later transitioned to multi-engine bombers and became a bomber operations test pilot after attending the Air Force Aerospace Research Pilot School at Edwards Air Force Base, Calif. He then was assigned to the flight crew for the planned Air Force Manned Orbital Laboratory in 1966. Upon cancellation of that program, the Air Force assigned Fullerton to NASA's astronaut corps in 1969. He served on the support crews for the Apollo 14, 15, 16 and 17 lunar missions, and was later assigned to one of the two flight crews that piloted the space shuttle prototype Enterprise during the Approach and Landing Test program at Dryden. He then logged some 382 hours in space when he flew on two early space shuttle missions, STS-3 on Columbia in 1982 and STS-51F on Challenger in 1985. He joined the flight crew branch at NASA Dryden after leaving the astronaut corps in 1986. During his 21 years at Dryden, Fullerton was project pilot on a number of high-profile research efforts, including the Propulsion Controlled Aircraft, the high-speed landing tests of

Impact of managed MediCal on California family practice programs.

PubMed

Zweifler, J A

2001-05-01

An important source of patients for California's family practice program is MediCal. During the past 5 years, MediCal has established a variety of capitated managed care plans. To assess the impact of California's managed MediCal program on the state's 38 family practice training programs. A cross-sectional, retrospective descriptive survey. A 3-page, 11-question survey was developed by family practice residency directors and staff from the California Academy of Family Physicians, San Francisco. The 38 family practice programs in existence in California in September 1997 were stratified by type of managed MediCal in their county and by type of sponsoring institution--university, county, community based, staff-model health maintenance organization, or managed care system. Of the 38 family practice programs, 27 responded; 19 of 27 programs participated in managed MediCal. The total number of family health center patients, and the percentage of MediCal patients (48%-60%) at family practice programs was similar when stratified by programs with and without managed MediCal and by type of sponsorship. Most programs reported that they were able to compete effectively, although most also reported increased administrative, nursing, and front office costs. Managed MediCal patients were directly assigned to residents in only 3 of 19 programs. The introduction of managed MediCal has not adversely affected the number of patients cared for in California's family practice programs. Continued vigilance regarding California family practice programs' involvement in managed MediCal, including collection of accurate data on the number of MediCal patients and the financial and educational implications for California's family practice programs, is warranted.

CAMPARE and Cal-Bridge: Two Institutional Networks Increasing Diversity in Astronomy

NASA Astrophysics Data System (ADS)

Rudolph, Alexander L.; Smecker-Hane, Tammy A.

2017-01-01

We describe two programs, CAMPARE and Cal-Bridge, with the common mission of increasing participation of groups traditionally underrepresented in astronomy, through summer research opportunities, in the case of CAMPARE, scholarships in the case of Cal-Bridge, and significant mentoring in both programs, creating a national impact on their numbers successfully pursuing a PhD in the field.In 7 years, the CAMPARE program has sent 80 students, >80% from underrepresented groups, to conduct summer research at one of 14 major research institutions throughout the country. The graduation rate among CAMPARE scholars is 98%, and of the CAMPARE scholars who have graduated with a Bachelor’s degree, more than 60% have completed or are pursuing graduate education in astronomy or a related field, at institutions including UCLA, UC Riverside, UC Irvine, UC Santa Barbara, USC, Stanford, Univ. of Arizona, Univ. of Washington, and the Fisk-Vanderbilt Master’s-to-PhD program.Now entering its third year, the Cal-Bridge program is a CSU-UC Bridge program comprised of over 75 physics and astronomy faculty from 5 University of California (UC), 9 California State University (CSU), and 14 California Community College (CCC) campuses in Southern California. In the first three years, 22 Cal-Bridge Scholars have been selected, including 11 Hispanic, 3 African-American and 8 female students, 5 of whom are from URM groups. Nineteen (19) of the 22 Cal-Bridge Scholars are first-generation college students. The entire first cohort of 4 Cal-Bridge scholars was accepted to one or more PhD programs in astronomy or physics, including UC Irvine, UC Santa Cruz, UC Davis, Michigan State, and Georgia State Universities. The second cohort of 8 Cal-Bridge scholars is applying to graduate schools this fall.Cal-Bridge provides much deeper mentoring and professional development experiences over the last two years of undergraduate and first year of graduate school to students from this diverse network of higher

Changes of ns-soot mixing states and shapes in an urban area during CalNex

NASA Astrophysics Data System (ADS)

Adachi, Kouji; Buseck, Peter R.

2013-05-01

Aerosol particles from megacities influence the regional and global climate as well as the health of their occupants. We used transmission electron microscopes (TEMs) to study aerosol particles collected from the Los Angeles area during the 2010 CalNex campaign. We detected major amounts of ns-soot, defined as consisting of carbon nanospheres, sulfate, sea salt, and organic aerosol (OA) and lesser amounts of brochosome particles from leaf hoppers. Ns-soot-particle shapes, mixing states, and abundances varied significantly with sampling times and days. Within plumes having high CO2 concentrations, much ns-soot was compacted and contained a relatively large number of carbon nanospheres. Ns-soot particles from both CalNex samples and Mexico City, the latter collected in 2006, had a wide range of shapes when mixed with other aerosol particles, but neither sets showed spherical ns-soot nor the core-shell configuration that is commonly used in optical calculations. Our TEM observations and light-absorption calculations of modeled particles indicate that, in contrast to ns-soot particles that are embedded within other materials or have the hypothesized core-shell configurations, those attached to other aerosol particles hardly enhance their light absorption. We conclude that the ways in which ns-soot mixes with other particles explain the observations of smaller light amplification by ns-soot coatings than model calculations during the CalNex campaign and presumably in other areas.

Fixed Combination Aerosol Foam Calcipotriene 0.005% (Cal) Plus Betamethasone Dipropionate 0.064% (BD) is More Efficacious than Cal or BD Aerosol Foam Alone for Psoriasis Vulgaris

PubMed Central

Tyring, Stephen; Bukhalo, Michael; Alonso-Llamazares, Javier; Olesen, Martin; Lowson, David; Yamauchi, Paul

2016-01-01

Objective: To evaluate the efficacy of fixed combination aerosol foam calcipotriene 0.005% (Cal) plus betamethasone dipropionate 0.064% (BD). Design: Patients were randomized (100:101:101) to receive Cal/BD foam, Cal foam, or BD foam once daily for four weeks. Setting: Twenty-eight United States centers. Participants: 302 patients (≥18 years) with Psoriasis vulgaris (plaque Psoriasis; ≥mild disease severity by physicians global assessment). Measurements: Treatment success of the body (“clear”/”almost clear” from baseline moderate/severe disease; “clear” from baseline mild disease). Involved scalp treatment success was an additional endpoint. Results: Most patients (76%) had moderate Psoriasis of the body (66% for scalp). At Week 4, 45 percent of Cal/BD foam patients achieved treatment success, significantly more than Cal foam (14.9%; OR 4.34 [95%CI 2.16,8.72] P<0.001) or BD foam (30.7%; 1.81 [1.00,3.26] P=0.047). Fifty-three percent of Cal/BD foam patients achieved treatment success of the scalp, significantly greater than Cal foam (35.6%; 1.91 [1.09,3.35] P=0.021), but not BD foam (47.5%; 1.24 [0.71,2.16] P=0.45). Mean modified Psoriasis area and severity index (population baseline 7.6) improved in all groups, with statistically significant differences in Week 4 Cal/BD foam score (2.37) versus Cal foam (4.39; mean difference -2.03 [-2.63][-1.43] P<0.001) and BD foam (3.37; -1.19 [-1.80][-0.59] P<0.001). Four (Cal/BD), 10 (Cal), and 8 (BD) adverse drug reactions were reported. Conclusion: Cal/BD foam was significantly more effective than Cal foam and BD foam in providing treatment success at Week 4 and effective on involved scalp. Trial registration: NCT01536938. PMID:27313822

A water-cannon salute from two Air Force fire trucks heralds NASA research pilot Gordon Fullerton's final mission as his NASA F/A-18 taxis beneath the spray.

NASA Image and Video Library

2007-12-21

Long-time NASA Dryden research pilot and former astronaut C. Gordon Fullerton capped an almost 50-year flying career, including more than 38 years with NASA, with a final flight in a NASA F/A-18 on Dec. 21, 2007. Fullerton and Dryden research pilot Jim Smolka flew a 90-minute pilot proficiency formation aerobatics flight with another Dryden F/A-18 and a Dryden T-38 before concluding with two low-level formation flyovers of Dryden before landing. Fullerton was honored with a water-cannon spray arch provided by two fire trucks from the Edwards Air Force Base fire department as he taxied the F/A-18 up to the Dryden ramp, and was then greeted by his wife Marie and several hundred Dryden staff after his final flight. Fullerton began his flying career with the U.S. Air Force in 1958 after earning bachelor's and master's degrees in mechanical engineering from the California Institute of Technology. Initially trained as a fighter pilot, he later transitioned to multi-engine bombers and became a bomber operations test pilot after attending the Air Force Aerospace Research Pilot School at Edwards Air Force Base, Calif. He then was assigned to the flight crew for the planned Air Force Manned Orbital Laboratory in 1966. Upon cancellation of that program, the Air Force assigned Fullerton to NASA's astronaut corps in 1969. He served on the support crews for the Apollo 14, 15, 16 and 17 lunar missions, and was later assigned to one of the two flight crews that piloted the space shuttle prototype Enterprise during the Approach and Landing Test program at Dryden. He then logged some 382 hours in space when he flew on two early space shuttle missions, STS-3 on Columbia in 1982 and STS-51F on Challenger in 1985. He joined the flight crew branch at NASA Dryden after leaving the astronaut corps in 1986. During his 21 years at Dryden, Fullerton was project pilot on a number of high-profile research efforts, including the Propulsion Controlled Aircraft, the high-speed landing tests of

Pilot Fullerton dons anti-g and ejection escape suit (EES) on middeck

NASA Image and Video Library

1982-03-31

S82-28922 (30 March 1982) --- Astronaut C. Gordon Fullerton, STS-3 pilot, floats upside down in the zero-gravity environment of the middeck area of the Earth-orbiting space shuttle Columbia as he dons a modified USAF high altitude pressure garment. The brownish ejection/escape suit is used by the astronauts at launch and entry. Most of the remainder of their mission time, they are attired in a blue constant-wear garment. Astronaut Jack R. Lousma, crew commander, took this picture with a 35mm camera. The crew spent eight full days in the reusable spacecraft, a shuttle record. Photo credit: NASA

Cal-Adapt: California's Climate Data Resource and Interactive Toolkit

NASA Astrophysics Data System (ADS)

Thomas, N.; Mukhtyar, S.; Wilhelm, S.; Galey, B.; Lehmer, E.

2016-12-01

Cal-Adapt is a web-based application that provides an interactive toolkit and information clearinghouse to help agencies, communities, local planners, resource managers, and the public understand climate change risks and impacts at the local level. The website offers interactive, visually compelling, and useful data visualization tools that show how climate change might affect California using downscaled continental climate data. Cal-Adapt is supporting California's Fourth Climate Change Assessment through providing access to the wealth of modeled and observed data and adaption-related information produced by California's scientific community. The site has been developed by UC Berkeley's Geospatial Innovation Facility (GIF) in collaboration with the California Energy Commission's (CEC) Research Program. The Cal-Adapt website allows decision makers, scientists and residents of California to turn research results and climate projections into effective adaptation decisions and policies. Since its release to the public in June 2011, Cal-Adapt has been visited by more than 94,000 unique visitors from over 180 countries, all 50 U.S. states, and 689 California localities. We will present several key visualizations that have been employed by Cal-Adapt's users to support their efforts to understand local impacts of climate change, indicate the breadth of data available, and delineate specific use cases. Recently, CEC and GIF have been developing and releasing Cal-Adapt 2.0, which includes updates and enhancements that are increasing its ease of use, information value, visualization tools, and data accessibility. We showcase how Cal-Adapt is evolving in response to feedback from a variety of sources to present finer-resolution downscaled data, and offer an open API that allows other organization to access Cal-Adapt climate data and build domain specific visualization and planning tools. Through a combination of locally relevant information, visualization tools, and access to

Solar CalPoly

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stannard, Sandra

The target budget of INhouse was about $650,000 for all materials and student expenses of the Solar Decathlon competition. In order to reach our goal, Cal Poly students and faculty worked with the College of Architecture and Environmental Design’s External Relations office to actively fundraise for INhouse. Students connected with Cal Poly alumni through phone calls, postal mail, email, and live presentations to reach as many alumni in the state of California as possible. Before construction begun, students and faculty met on a weekly basis to determine what brands of materials for the home to use and who would bemore » responsible for reaching out to the company to seek a donation. Our College of Architecture and Environmental Design’s administration was essential in helping us fundraise. For some time, the college was hoping to depend on about half of our fundraising expenses to be covered through the sale of INhouse. However, plans to sell the home fell through during the design development phase; the college turned to the sale of a different asset in to help us meet our goal. If we were to do this project again, completing the design concept and securing a future location of our home sooner would have enhanced our fundraising activities.« less

More than 200 Dryden staff formed two long lines on the Dryden ramp to greet retired research pilot Gordon Fullerton after his final flight in a NASA F/A-18.

NASA Image and Video Library

2007-12-21

Long-time NASA Dryden research pilot and former astronaut C. Gordon Fullerton capped an almost 50-year flying career, including more than 38 years with NASA, with a final flight in a NASA F/A-18 on Dec. 21, 2007. Fullerton and Dryden research pilot Jim Smolka flew a 90-minute pilot proficiency formation aerobatics flight with another Dryden F/A-18 and a Dryden T-38 before concluding with two low-level formation flyovers of Dryden before landing. Fullerton was honored with a water-cannon spray arch provided by two fire trucks from the Edwards Air Force Base fire department as he taxied the F/A-18 up to the Dryden ramp, and was then greeted by his wife Marie and several hundred Dryden staff after his final flight. Fullerton began his flying career with the U.S. Air Force in 1958 after earning bachelor's and master's degrees in mechanical engineering from the California Institute of Technology. Initially trained as a fighter pilot, he later transitioned to multi-engine bombers and became a bomber operations test pilot after attending the Air Force Aerospace Research Pilot School at Edwards Air Force Base, Calif. He then was assigned to the flight crew for the planned Air Force Manned Orbital Laboratory in 1966. Upon cancellation of that program, the Air Force assigned Fullerton to NASA's astronaut corps in 1969. He served on the support crews for the Apollo 14, 15, 16 and 17 lunar missions, and was later assigned to one of the two flight crews that piloted the space shuttle prototype Enterprise during the Approach and Landing Test program at Dryden. He then logged some 382 hours in space when he flew on two early space shuttle missions, STS-3 on Columbia in 1982 and STS-51F on Challenger in 1985. He joined the flight crew branch at NASA Dryden after leaving the astronaut corps in 1986. During his 21 years at Dryden, Fullerton was project pilot on a number of high-profile research efforts, including the Propulsion Controlled Aircraft, the high-speed landing tests of

NASA Dryden research pilot Gordon Fullerton flies his final mission in NASA F/A-18B #852 in formation with NASA F/A-18A #850 on Dec. 21, 2007.

NASA Image and Video Library

2007-12-21

Long-time NASA Dryden research pilot and former astronaut C. Gordon Fullerton capped an almost 50-year flying career, including more than 38 years with NASA, with a final flight in a NASA F/A-18 on Dec. 21, 2007. Fullerton and Dryden research pilot Jim Smolka flew a 90-minute pilot proficiency formation aerobatics flight with another Dryden F/A-18 and a Dryden T-38 before concluding with two low-level formation flyovers of Dryden before landing. Fullerton was honored with a water-cannon spray arch provided by two fire trucks from the Edwards Air Force Base fire department as he taxied the F/A-18 up to the Dryden ramp, and was then greeted by his wife Marie and several hundred Dryden staff after his final flight. Fullerton began his flying career with the U.S. Air Force in 1958 after earning bachelor's and master's degrees in mechanical engineering from the California Institute of Technology. Initially trained as a fighter pilot, he later transitioned to multi-engine bombers and became a bomber operations test pilot after attending the Air Force Aerospace Research Pilot School at Edwards Air Force Base, Calif. He then was assigned to the flight crew for the planned Air Force Manned Orbital Laboratory in 1966. Upon cancellation of that program, the Air Force assigned Fullerton to NASA's astronaut corps in 1969. He served on the support crews for the Apollo 14, 15, 16 and 17 lunar missions, and was later assigned to one of the two flight crews that piloted the space shuttle prototype Enterprise during the Approach and Landing Test program at Dryden. He then logged some 382 hours in space when he flew on two early space shuttle missions, STS-3 on Columbia in 1982 and STS-51F on Challenger in 1985. He joined the flight crew branch at NASA Dryden after leaving the astronaut corps in 1986. During his 21 years at Dryden, Fullerton was project pilot on a number of high-profile research efforts, including the Propulsion Controlled Aircraft, the high-speed landing tests of sp

Measurements of Gases and Aerosols during 2010Cal-Mex

NASA Astrophysics Data System (ADS)

Zheng, J.; Zhang, R.; Molina, L.

2012-04-01

The major goal of the collaborative Cal-Mex 2010 research project is to assess the sources and processing of emissions along the California-Mexico border region and their effects on regional air quality and climate in order to provide scientific information to decision makers of both nations when addressing these two inter-related issues. During the Cal-Mex 2010 field study, the TAMU teams have collected extensive data sets from Tijuana/San Diego border, including volatile organic compounds (VOCs), gaseous sulfuric acid (H2SO4) and a suite set of physical and chemical parameters of aerosols. This comprehensive data set requires additional effort to process and analyze the measurements of gases and aerosols during Cal-Mex 2010. In this talk, preliminary data analysis of gases and aerosols will be presented, including VOCs and particle mixing states, morphology, and effective densities.

CalNex Observational Data

EPA Pesticide Factsheets

Observations made during the 2010 CalNex measurement campaign. This dataset is associated with the following publication:Woody , M., K. Baker , P. Hayes, J. Jimenez, B. Koo, and H. Pye. Understanding sources of organic aerosol during CalNex-2010 using the CMAQ-VBS. Atmospheric Chemistry and Physics. Copernicus Publications, Katlenburg-Lindau, GERMANY, 16: 4081-4100, (2016).

ZeroCal: Automatic MAC Protocol Calibration

NASA Astrophysics Data System (ADS)

Meier, Andreas; Woehrle, Matthias; Zimmerling, Marco; Thiele, Lothar

Sensor network MAC protocols are typically configured for an intended deployment scenario once and for all at compile time. This approach, however, leads to suboptimal performance if the network conditions deviate from the expectations. We present ZeroCal, a distributed algorithm that allows nodes to dynamically adapt to variations in traffic volume. Using ZeroCal, each node autonomously configures its MAC protocol at runtime, thereby trying to reduce the maximum energy consumption among all nodes. While the algorithm is readily usable for any asynchronous low-power listening or low-power probing protocol, we validate and demonstrate the effectiveness of ZeroCal on X-MAC. Extensive testbed experiments and simulations indicate that ZeroCal quickly adapts to traffic variations. We further show that ZeroCal extends network lifetime by 50% compared to an optimal configuration with identical and static MAC parameters at all nodes.

CAMPARE and Cal-Bridge: Two Institutional Networks Increasing Diversity in Astronomy

NASA Astrophysics Data System (ADS)

Rudolph, Alexander L.; Impey, Chris David; Smecker-Hane, Tammy A.

2016-01-01

We describe two programs, CAMPARE and Cal-Bridge, with the common mission of increasing participation of groups traditionally underrepresented in astronomy, through summer research opportunities, in the case of CAMPARE, scholarships in the case of Cal-Bridge, and significant mentoring in both programs, leading to an increase in their numbers successfully pursuing a PhD in the field.In 6 years, the CAMPARE program has sent 62 students, >85% from underrepresented groups, to conduct summer research at one of twelve major research institutions in California, Arizona, and Wyoming. The graduation rate among CAMPARE scholars is 97%, and of the 37 CAMPARE scholars who have graduated with a Bachelor's degree, almost 60% (21) have completed or are pursuing graduate education in astronomy or a related field, at institutions including UCLA, USC, UC Riverside, Stanford, Univ. of Rochester, Georgia Tech, Kent State, Indiana Univ., Univ. of Oregon, Syracuse, and the Fisk-Vanderbilt Master's-to-PhD program. The Cal-Bridge program is a CSU-UC Bridge program comprised of faculty form 5 University of California (UC), 8 California State University (CSU), and 8 California Community College (CCC) campuses in Southern California. Cal-Bridge provides much deeper mentoring and professional development experiences over the last two years of undergraduate and first year of graduate school to students from this diverse network of higher education institutions. Cal-Bridge Scholars benefit from financial support, intensive, joint mentoring by CSU and UC faculty, professional development workshops, and exposure to research opportunities at the participating UC campuses.

Fond Memories of Cal Council

ERIC Educational Resources Information Center

Minnis, Douglas L.

2015-01-01

This article describes the author's personal involvement in the California Council for the Education of Teachers (Cal Council), beginning in 1960 and spanning four decades, which involved associations with key people in California teacher education and credentialing. The Cal Council was organized for leaders in teacher education from the…

PAS-cal: a Generic Recombinant Peptide Calibration Standard for Mass Spectrometry

NASA Astrophysics Data System (ADS)

Breibeck, Joscha; Serafin, Adam; Reichert, Andreas; Maier, Stefan; Küster, Bernhard; Skerra, Arne

2014-08-01

We describe the design, preparation, and mass-spectrometric characterization of a new recombinant peptide calibration standard with uniform biophysical and ionization characteristics for mass spectrometry. "PAS-cal" is an artificial polypeptide concatamer of peptide cassettes with varying lengths, each composed of the three small, chemically stable amino acids Pro, Ala, and Ser, which are interspersed by Arg residues to allow site-specific cleavage with trypsin. PAS-cal is expressed at high yields in Escherichia coli as a Small Ubiquitin-like MOdifier (SUMO) fusion protein, which is easily purified and allows isolation of the PAS-cal moiety after SUMO protease cleavage. Upon subsequent in situ treatment with trypsin, the PAS-cal polypeptide yields a set of four defined homogeneous peptides in the range from 2 to 8 kDa with equal mass spacing. ESI-MS analysis revealed a conveniently interpretable raw spectrum, which after deconvolution resulted in a very simple pattern of four peaks with similar ionization signals. MALDI-MS analysis of a PAS-cal peptide mixture comprising both the intact polypeptide and its tryptic fragments revealed not only the four standard peptides but also the singly and doubly charged states of the intact concatamer as well as di- and trimeric adduct ion species between the peptides, thus augmenting the observable m/z range. The advantageous properties of PAS-cal are most likely a result of the strongly hydrophilic and conformationally disordered PEG-like properties of the PAS sequences. Therefore, PAS-cal offers an inexpensive and versatile recombinant peptide calibration standard for mass spectrometry in protein/peptide bioanalytics and proteomics research, the composition of which may be further adapted to fit individual needs.

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Science.gov Websites

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A CAL-Based Undergraduate Genetics Course.

ERIC Educational Resources Information Center

Garbutt, K.; And Others

1979-01-01

Describes a second-year undergraduate practical course in quantitative genetics and biometrics, based upon computer-assisted learning (CAL); and discusses the educational benefits of the course, some problems encountered, and some implications of the extensive use of CAL. (Author/CMV)

Final Report Feasibility Study for the California Wave Energy Test Center (CalWavesm)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blakeslee, Samuel Norman; Toman, William I.; Williams, Richard B.

The California Wave Energy Test Center (CalWave) Feasibility Study project was funded over multiple phases by the Department of Energy to perform an interdisciplinary feasibility assessment to analyze the engineering, permitting, and stakeholder requirements to establish an open water, fully energetic, grid connected, wave energy test center off the coast of California for the purposes of advancing U.S. wave energy research, development, and testing capabilities. Work under this grant included wave energy resource characterization, grid impact and interconnection requirements, port infrastructure and maritime industry capability/suitability to accommodate the industry at research, demonstration and commercial scale, and macro and micro sitingmore » considerations. CalWave Phase I performed a macro-siting and down-selection process focusing on two potential test sites in California: Humboldt Bay and Vandenberg Air Force Base. This work resulted in the Vandenberg Air Force Base site being chosen as the most favorable site based on a peer reviewed criteria matrix. CalWave Phase II focused on four siting location alternatives along the Vandenberg Air Force Base coastline and culminated with a final siting down-selection. Key outcomes from this work include completion of preliminary engineering and systems integration work, a robust turnkey cost estimate, shoreside and subsea hazards assessment, storm wave analysis, lessons learned reports from several maritime disciplines, test center benchmarking as compared to existing international test sites, analysis of existing applicable environmental literature, the completion of a preliminary regulatory, permitting and licensing roadmap, robust interaction and engagement with state and federal regulatory agency personnel and local stakeholders, and the population of a Draft Federal Energy Regulatory Commission (FERC) Preliminary Application Document (PAD). Analysis of existing offshore oil and gas infrastructure was also

The PlusCal Algorithm Language

NASA Astrophysics Data System (ADS)

Lamport, Leslie

Algorithms are different from programs and should not be described with programming languages. The only simple alternative to programming languages has been pseudo-code. PlusCal is an algorithm language that can be used right now to replace pseudo-code, for both sequential and concurrent algorithms. It is based on the TLA + specification language, and a PlusCal algorithm is automatically translated to a TLA + specification that can be checked with the TLC model checker and reasoned about formally.

The Long Run Impacts of Merit Aid: Evidence from California's Cal Grant. CEPA Working Paper No. 16-13

ERIC Educational Resources Information Center

Bettinger, Eric; Gurantz, Oded; Kawano, Laura; Sacerdote, Bruce

2016-01-01

We examine the impacts of being awarded a Cal Grant, among the most generous state merit aid programs. We exploit variation in eligibility rules using GPA and family income cutoffs that are ex ante unknown to applicants. Cal Grant eligibility increases degree completion by 2 to 5 percentage points in our reduced form estimates. Cal Grant also…

The Efficiency of Delone Coverings of the Canonical Tilings cal T}(*(A_4)) -> T^*(A4) and cal T}(*(D_6)) -> T^*(D6)

NASA Astrophysics Data System (ADS)

Papadopolos, Zorka; Kasner, Gerald

This chapter is devoted to the coverings of the two quasiperiodic canonical tilings cal T}(*(A_4)) -> T^*(A4) and cal T}(*(D_6)) equiv {cal T}(*(2F)) -> T^*(D6) T^*(2F), obtained by projection from the root lattices A4 and D6, respectively. In the first major part of this chapter, in Sect. 5.2, we shall introduce a Delone covering cal C}(s_{{cal) T}(*(A_4)}) -> C^sT^*(A4) of the 2-dimensional decagonal tiling cal T}(*(A_4)) -> T^*(A4). In the second major part of this chapter, Sect. 5.3, we summarize the results related to the Delone covering of the icosahedral tiling cal T}(*(D_6)) -> T^*(D6), cal C}_{{cal T}(*(D_6)}) -> CT^*(D6) and determine the zero-, single-, and double- deckings and the resulting thickness of the covering. In the conclusions section, we give some suggestions as to how the definition of the Delone covering might be changed in order to reach some real (full) covering of the icosahedral tiling cal T}(*(D_6)) -> T^*(D6). In Section 5.2 the definition of the Delone covering is also changed in order to avoid an unnecessary large thickness of the covering.

RoboCal: An automated nondestructive assay system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Staley, H.C.; Hollen, R.M.; Bonner, C.A.

1990-01-01

The manager of a facility handling special nuclear material (SNM) is caught in a squeeze between increased state and federal regulations and tighter funding. RoboCal uses a robot to manipulate canisters containing SNM to lower worker radiation exposure and to provide increased utilization of expensive assay equipment. In addition, it helps with accountability and material tracking. It consists of a hierarchical network of more than a dozen computers and provides a single point of contact for the user to accomplish multiple assays.

CalWater 2015 — Atmospheric Rivers and Aerosol Impacts on Precipitation

NASA Astrophysics Data System (ADS)

Spackman, J. R.; Ralph, F. M.; Prather, K. A.; Cayan, D.; DeMott, P. J.; Dettinger, M. D.; Doyle, J. D.; Fairall, C. W.; Leung, L. R.; Rosenfeld, D.; Rutledge, S. A.; Waliser, D. E.; White, A. B.

2015-12-01

The CalWater 2015 field experiment was conducted between January and March and consisted of more than fifty science flights, a major research cruise, and continuous ground-based observations coordinated to study phenomena driving the incidence of extreme precipitation events and the variability of water supply along the West Coast of the United States. CalWater 2015 examined key processes linked to (1) atmospheric rivers (ARs) in delivering much of the precipitation associated with major winter storms, and (2) aerosols, originating from local sources as well as from remote continents, within and between storms and their modulating effects on precipitation on the U.S. West Coast. As part of a large interagency field effort including NOAA, DOE, NASA, NSF, and the Naval Research Laboratory, four research aircraft from three government agencies were deployed in coordination with the oceangoing NOAA Ronald H. Brown and were equipped with meteorological and chemical observing systems in near-shore regions of California and the eastern Pacific. At the same time, ground-based measurements from NOAA's HydroMeteorological Testbed (HMT) network on the U.S. West Coast and a major NSF-supported observing site for aerosols and microphysics at Bodega Bay, California provided continuous near surface-level meteorological and chemical observations, respectively, during CalWater 2015. The DOE-sponsored ARM Cloud Aerosol and Precipitation Experiment (ACAPEX) was executed in close coordination with NOAA and NASA facilities and deployed airborne and ship-based observing systems. This presentation summarizes the objectives, implementation strategy, data acquisitions, and some preliminary results from CalWater 2015 addressing science gaps associated with (1) the evolution and structure of ARs including cloud and precipitation processes and air-sea interaction, and (2) aerosol interaction with ARs and the impact on precipitation, including locally-generated aerosol effects on orographic

CubiCal: Suite for fast radio interferometric calibration

NASA Astrophysics Data System (ADS)

Kenyon, J. S.; Smirnov, O. M.; Grobler, T. L.; Perkins, S. J.

2018-05-01

CubiCal implements several accelerated gain solvers which exploit complex optimization for fast radio interferometric gain calibration. The code can be used for both direction-independent and direction-dependent self-calibration. CubiCal is implemented in Python and Cython, and multiprocessing is fully supported.

Research Pilot C. Gordon Fullerton in Cockpit of TU-144LL SST Flying Laboratory

NASA Technical Reports Server (NTRS)

1998-01-01

NASA Research pilot C. Gordon Fullerton sits in cockpit of TU-144LL SST Flying Laboratory. Fullerton was one of two NASA pilots who flew the aircraft as part of a joint high speed research program. NASA teamed with American and Russian aerospace industries for an extended period in a joint international research program featuring the Russian-built Tu-144LL supersonic aircraft. The object of the program was to develop technologies for a proposed future second-generation supersonic airliner to be developed in the 21st Century. The aircraft's initial flight phase began in June 1996 and concluded in February 1998 after 19 research flights. A shorter follow-on program involving seven flights began in September 1998 and concluded in April 1999. All flights were conducted in Russia from Tupolev's facility at the Zhukovsky Air Development Center near Moscow. The centerpiece of the research program was the Tu 144LL, a first-generation Russian supersonic jetliner that was modified by its developer/builder, Tupolev ANTK (aviatsionnyy nauchno-tekhnicheskiy kompleks-roughly, aviation technical complex), into a flying laboratory for supersonic research. Using the Tu-144LL to conduct flight research experiments, researchers compared full-scale supersonic aircraft flight data with results from models in wind tunnels, computer-aided techniques, and other flight tests. The experiments provided unique aerodynamic, structures, acoustics, and operating environment data on supersonic passenger aircraft. Data collected from the research program was being used to develop the technology base for a proposed future American-built supersonic jetliner. Although actual development of such an advanced supersonic transport (SST) is currently on hold, commercial aviation experts estimate that a market for up to 500 such aircraft could develop by the third decade of the 21st Century. The Tu-144LL used in the NASA-sponsored research program was a 'D' model with different engines than were used in

Engineering Students' Use of Computer Assisted Learning (CAL)

ERIC Educational Resources Information Center

Huczynski, Andrzej; Johnston, Scott Paul

2005-01-01

This study examines the use of Computer Assisted Learning (CAL) by undergraduate engineering students studying a business and management course. Discussing both the relationship between management and engineering and CAL applied to engineering education, this study is based on a survey of 82 undergraduates and adopts a quantitative research…

26-Hours at Cal Poly: A Recruitment Strategy Targeting Underrepresented Groups.

ERIC Educational Resources Information Center

Flores, Bob; Kellogg, Bill

The Agriculture Education Department at California Polytechnic State University conducted a program to recruit Black and Hispanic students for the school's agriculture programs during spring 1988 and twice since then. High school sophomores and juniors in Los Angeles were invited to Cal Poly for a 26-hour program of workshops designed to include a…

Chronological reconstruction of eolianites and transversal mobile dunes of northwest coast of Ceará State - Brazil, in the last 3000 cal yrs BP

NASA Astrophysics Data System (ADS)

Castro, João Wagner Alencar; Malta, Julia Varella; Miguel, Lucas Lavo Antonio Jimo; Cabral, Caique Lima; Passemilio, Alvaro Balmant

2017-10-01

Dunefields are very common in the northern coastal zone of northeast Brazil. They have the potential to yield important information about paleoclimate, paleo-winds and regional winds and their response to sea-level fluctuations during the Holocene. We reconstructed the coastal dunes geochronological evolution of northwest Ceará State - Brazil, in the last 3000 cal yrs BP, using detailed analyses of lithostratigraphy, microfossil (foraminifera), wind regime, dune monitoring and 8 radiocarbon dates. The chronology was based on 14C dating in eolianites and monitoring transversal mobile dunes movement processes. Radiocarbon date results indicated that the dunes corresponding to eolianites revealed ages between 2760-2480 and 980-750 cal yrs BP, suggesting that the vast transversal mobile dunefields were formed after this period in similar condition to the current sea-level. We considered that the material transportation by the prevailing east winds towards the transversal dunes is estimated in the order of 11.0 m/year, thus the current aeolian system is less than 1000 yrs BP.

Final Report Feasibility Study for the California Wave Energy Test Center (CalWavesm) - Volume #2 - Appendices #16-17

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dooher, Brendan; Toman, William I.; Davy, Doug M.

The California Wave Energy Test Center (CalWave) Feasibility Study project was funded over multiple phases by the Department of Energy to perform an interdisciplinary feasibility assessment to analyze the engineering, permitting, and stakeholder requirements to establish an open water, fully energetic, grid connected, wave energy test center off the coast of California for the purposes of advancing U.S. wave energy research, development, and testing capabilities. Work under this grant included wave energy resource characterization, grid impact and interconnection requirements, port infrastructure and maritime industry capability/suitability to accommodate the industry at research, demonstration and commercial scale, and macro and micro sitingmore » considerations. CalWave Phase I performed a macro-siting and down-selection process focusing on two potential test sites in California: Humboldt Bay and Vandenberg Air Force Base. This work resulted in the Vandenberg Air Force Base site being chosen as the most favorable site based on a peer reviewed criteria matrix. CalWave Phase II focused on four siting location alternatives along the Vandenberg Air Force Base coastline and culminated with a final siting down-selection. Key outcomes from this work include completion of preliminary engineering and systems integration work, a robust turnkey cost estimate, shoreside and subsea hazards assessment, storm wave analysis, lessons learned reports from several maritime disciplines, test center benchmarking as compared to existing international test sites, analysis of existing applicable environmental literature, the completion of a preliminary regulatory, permitting and licensing roadmap, robust interaction and engagement with state and federal regulatory agency personnel and local stakeholders, and the population of a Draft Federal Energy Regulatory Commission (FERC) Preliminary Application Document (PAD). Analysis of existing offshore oil and gas infrastructure was also

The Return of Two-Class Medicine—III Effects of Medi-Cal Reform

PubMed Central

Waitzkin, Howard

1985-01-01

California's drastic Medi-Cal reforms have created great difficulties in health care for the poor. Patients' clinical problems seldom are apparent in descriptions of changes in public insurance programs. Rapidly escalating costs of Medi-Cal led to irresistible pressures for reform, especially from the business community. The new Medi-Cal regulations provide for prospective contracts with hospitals for inpatient services, the transfer of “Medically Indigent Adults” to the responsibility of county governments and various other straightforward funding cutbacks. Confusion, disruption of services and adverse health outcomes have accompanied the Medi-Cal reforms. PMID:3892917

USS Cal Builders, Inc. Information Sheet

EPA Pesticide Factsheets

USS Cal Builders, Inc. (the Company) is located in Stanton, California. The settlement involves renovation activities conducted at property constructed prior to 1978, located in San Francisco, California.

Hospital Selective Contracting without Consumer Choice: What Can We Learn from Medi-Cal?

ERIC Educational Resources Information Center

Bamezai, Anil; Melnick, Glenn A.; Mann, Joyce M.; Zwanziger, Jack

2003-01-01

In the selective contracting era, consumer choice has generally been absent in most state Medicaid programs, including California's (called Medi-Cal). In a setting where beneficiary exit is not a threat, a large payer may have both the incentives and the ability to exercise undue market power, potentially exposing an already vulnerable population…

OSD CALS Architecture Master Plan Study. Concept Paper. Security. Volume 38

DOT National Transportation Integrated Search

1989-07-01

Developing and executing a well-thought-out security policy is critical to the success of CALS. Without appropriate security measures, the integration of technology, organizations, functions, and data envisioned as Phase II CALS can not occur. Theref...

CALS Infrastructure Analysis. Draft. Volume 21

DOT National Transportation Integrated Search

1990-03-01

This executive overview to the DoD CALS Infrastructure Analysis Report summarizes the Components' current effort to modernize the DoD technical data infrastructure. This infrastructure includes all existing and planned capabilities to acquire, manage...

Views of a Cal/OSHA Inspector.

PubMed

Oudiz, Jack

2009-01-01

Retiring CAL/OSHA Industrial Hygienist and Senior Safety Engineer Jack Oudiz offers his thoughts in the nature of a voluntary "exit interview" on his years working for the agency and its performance in its mission.

An Interaction of Screen Colour and Lesson Task in CAL

ERIC Educational Resources Information Center

Clariana, Roy B.

2004-01-01

Colour is a common feature in computer-aided learning (CAL), though the instructional effects of screen colour are not well understood. This investigation considers the effects of different CAL study tasks with feedback on posttest performance and on posttest memory of the lesson colour scheme. Graduate students (n=68) completed a computer-based…

Estimated contributions of primary and secondary organic aerosol from fossil fuel combustion during the CalNex and Cal-Mex campaigns

NASA Astrophysics Data System (ADS)

Guzman-Morales, J.; Frossard, A. A.; Corrigan, A. L.; Russell, L. M.; Liu, S.; Takahama, S.; Taylor, J. W.; Allan, J.; Coe, H.; Zhao, Y.; Goldstein, A. H.

2014-05-01

Observations during CalNex and Cal-Mex field campaigns at Bakersfield, Pasadena, Tijuana, and on board the R/V Atlantis show a substantial contribution of fossil fuel emissions to the ambient particle organic mass (OM). At least two fossil fuel combustion (FFC) factors with a range of contributions of oxidized organic functional groups were identified at each site and accounted for 60-88% of the total OM. Additional marine, vegetative detritus, and biomass burning or biogenic sources contribute up to 40% of the OM. Comparison of the FTIR spectra of four different unburned fossil fuels (gasoline, diesel, motor oil, and ship diesel) with PMF factors from ambient samples shows absorbance peaks from the fuels are retained in organic aerosols, with the spectra of all of the FFC factors containing at least three of the four characteristic alkane peaks observed in fuel standards at 2954, 2923, 2869 and 2855 cm-1. Based on this spectral similarity, we estimate the primary OM from FFC sources for each site to be 16-20%, with secondary FFC OM accounting for an additional 42-62%. Two other methods for estimating primary OM that use carbon monoxide (CO) and elemental carbon (EC) as tracers of primary organic mass were investigated, but both approaches were problematic for the CalNex and Cal-Mex urban sites because they were influenced by multiple emission sources that had site-specific and variable initial ratios to OM. For example, using the ΔPOM/ΔCO ratio of 0.0094 μg ppb V-1 proposed by other studies produces unrealistically high estimates of primary FFC OM of 55-100%.

OSD CALS Architecture Master Plan Study. Concept Paper. Configuration Management. Volume 28

DOT National Transportation Integrated Search

1989-10-01

The mission of CALS is to enhance operational readiness of DoD weapon systems through application of information technology to the management of technical information. CALS will automate the current paper-intensive processes involved in weapon system...

David Georgi's Cal Council Presidency

ERIC Educational Resources Information Center

Georgi, David

2015-01-01

When the author was asked to write a mini-memoir about his time as Cal Council president, his first thought was "Now, when exactly was that?" He says that pretty much summarizes the quality of his memory these days. The author's first contact with the California Council on the Education of Teachers was back in the 1970s when the…

78 FR 1264 - CalAmp Wireless Networks Corporation, Waseca, MN; Notice of Negative Determination Regarding...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,646] CalAmp Wireless Networks...; CalAmp Wireless Networks Corporation, Waseca, Minnesota; expires on December 2, 2013). Conclusion Due to the eligibility of workers and former workers of CalAmp Wireless Networks Corporation, Waseca...

Data Management Standards in Computer-aided Acquisition and Logistic Support (CALS)

NASA Technical Reports Server (NTRS)

Jefferson, David K.

1990-01-01

Viewgraphs and discussion on data management standards in computer-aided acquisition and logistic support (CALS) are presented. CALS is intended to reduce cost, increase quality, and improve timeliness of weapon system acquisition and support by greatly improving the flow of technical information. The phase 2 standards, industrial environment, are discussed. The information resource dictionary system (IRDS) is described.

The Cal-Bridge Program: Supporting Diverse Graduate Students in Astrophysics

NASA Astrophysics Data System (ADS)

Smecker-Hane, Tammy A.; Rudolph, Alexander L.; Abazajian, Kevork; Povich, Matthew S.

2018-06-01

The mission of the Cal-Bridge program is to increase the number of underrepresented minority and women students completing a bachelor’s degree and entering a PhD program in astronomy, physics, or closely-related fields. To do so, we have built a network of faculty at diverse higher education institutions, including University of California (UC) campuses, California State Universities (CSUs), and community colleges dedicated to this goal. Students selected for our program are known as Cal-Bridge Scholars, and we give them a wide variety of support: (1) financial scholarships in their junior/senior years at CSU and their first year of graduate school at a UC, (2) intensive mentoring by a pair of CSU and UC faculty members, (3) tutoring, (4) professional development workshops, (5) exposure to research opportunities at various universities, and (6) membership in a growing cohort of like-minded students. In this poster, we report on our work in designing an effective mentoring program and developing tools like our mentoring and graduate application handbooks, and we discuss our tutoring program and the professional development workshops we have designed, and we report on their effectiveness. Funding for this program is provided by NSF-SSTEM Grant #1356133.

Navy/Marine Corps Manager’s Desktop Guide for CALS Implementation. 2nd Edition

DTIC Science & Technology

1993-06-30

significant process and productivity that CALS initiatives are providing within the Navy infrastructure. CALS programs are on-line and working in today’s Navy...era of declining budgets, CALS is most important in enhancing logistic support productivity to maintain operations and improve readiness. Our...is to be accomplished through the general adoption of a set of procedures and staridards for the production , access, management, maintenance, and

The Cal-Bridge Program: Increasing the Gender and Ethnic Diversity of Astrophysics Students in Southern California

NASA Astrophysics Data System (ADS)

Smecker-Hane, Tammy A.; Rudolph, Alexander L.

2016-06-01

The mission of the Cal-Bridge program is to increase the number of underrepresented minority and women students completing a bachelor’s degree and entering a PhD program in astronomy, physics, or closely-related fields. The program has created a network of faculty at diverse higher education institutions, including 5 University of California (UC) campuses, 9 California State Universities (CSUs), and 10 community colleges in southern California, dedicated to this goal. Students selected for the program are know as “Cal-Bridge Scholars” and they are given a wide variety of support: (1) scholarships in their junior/senior years at CSU and their first year of graduate school at a UC, (2) intensive mentoring by a pair of CSU and UC faculty members, (3) tutoring, when needed, (4) professional development workshops, (5) exposure to research opportunities at various universities, and (6) membership in a growing cohort of like-minded students. We report on the structure of our program, lessons learned with our current 12 Cal-Bridge scholars, and the results of our first two years of operation. Funding for this program is provided by NSF-SSTEM Grant #1356133.

Computer-aided acquisition and logistics support (CALS): Concept of Operations for Depot Maintenance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bourgeois, N.C.; Greer, D.K.

1993-04-01

This CALS Concept of Operations for Depot Maintenance provides the foundation strategy and the near term tactical plan for CALS implementation in the depot maintenance environment. The user requirements enumerated and the overarching architecture outlined serve as the primary framework for implementation planning. The seamless integration of depot maintenance business processes and supporting information systems with the emerging global CALS environment will be critical to the efficient realization of depot user's information requirements, and as, such will be a fundamental theme in depot implementations.

Paleoenvironmental and Paleoclimate Changes Since 21,000 Cal Years BP in the Northeastern part of Brazil Inferred From Sediment Records in Lagoa do Caco (Maranhao State, Brazil)

NASA Astrophysics Data System (ADS)

Sifeddine, A.; Meyers, P. A.; Gustavo, A.; Spadano Albuquerque, A. L.; Turcq, B.; Campbello Cordeiro, R.; Abrao, J. J.

2004-12-01

Two cores from Caco Lake, Maranhao State (North Brazil) record different histories of sediment accumulation on the margin and center of the lake that reflect changes in lake level. Seismic profiles, mineralogy and organic geochemical studies, backed by radiocarbon dating, reveal variable climatic and environmental conditions over the last 21 Cal Kyr BP. During the Last Glacial Maximum, regional climate was predominantly dry but was interrupted by short humid phases as reflected by a succession of very thin layers of sand and organic matter. The late glacial climate was relatively wet and included two rapid lake-level increases accompanied by forest expansion. The two wet phases were separated by a phase where the lake level remained stable and the forest changes were marked by the development of cool "Podocarpus" forest. These humid climate periods differed significantly from present warm tropical conditions.. The Holocene period is characterized by progressive increase of lake level, which reaches his maximum at around 7,000 Cal years BP. The period between 4,000 Cal years BP and the present shows high variability in lake level. Comparing with other South American and African records, we conclude that Late Glacial humid conditions were controlled by intensification of the ITCZ or shifts of its position, resulting in southeasterly trade wind variations and in interconnection between northern South America and the Atlantic tropical ocean-atmosphere system. The climatic variability during the Holocene is probably the result of sub-Milankovitch solar cycles and regional responses to these global forcings that are related to Atlantic and Pacific variability and their interconnections.

The X-ray eclipse of the LMC binary CAL 87

NASA Technical Reports Server (NTRS)

Schmidtke, P. C.; Mcgrath, T. K.; Cowley, A. P.; Frattare, L. M.

1993-01-01

ROSAT-PSPC observations of the LMC eclipsing binary CAL 87 show a short-duration, shallow X-ray eclipse which coincides in phase with the primary optical minimum. Characteristics of the eclipse suggest the X-ray emitting region is only partially occulted. Similarities with the eclipse of the accretion-disk corona in X 1822-37 are discussed. However, no temperature variation through eclipse is found for CAL 87. A revised orbital period, combining published data and recent optical photometry, is given.

CALS Baseline Architecture Analysis of Weapons System. Technical Information: Army, Draft. Volume 8

DOT National Transportation Integrated Search

1989-09-01

This effort was performed to provide a common framework for analysis and planning of CALS initiatives across the military services, leading eventually to the development of a common DoD-wide architecture for CALS. This study addresses Army technical ...

CalQuo: automated, simultaneous single-cell and population-level quantification of global intracellular Ca2+ responses.

PubMed

Fritzsche, Marco; Fernandes, Ricardo A; Colin-York, Huw; Santos, Ana M; Lee, Steven F; Lagerholm, B Christoffer; Davis, Simon J; Eggeling, Christian

2015-11-13

Detecting intracellular calcium signaling with fluorescent calcium indicator dyes is often coupled with microscopy techniques to follow the activation state of non-excitable cells, including lymphocytes. However, the analysis of global intracellular calcium responses both at the single-cell level and in large ensembles simultaneously has yet to be automated. Here, we present a new software package, CalQuo (Calcium Quantification), which allows the automated analysis and simultaneous monitoring of global fluorescent calcium reporter-based signaling responses in up to 1000 single cells per experiment, at temporal resolutions of sub-seconds to seconds. CalQuo quantifies the number and fraction of responding cells, the temporal dependence of calcium signaling and provides global and individual calcium-reporter fluorescence intensity profiles. We demonstrate the utility of the new method by comparing the calcium-based signaling responses of genetically manipulated human lymphocytic cell lines.

CubiCal - Fast radio interferometric calibration suite exploiting complex optimisation

NASA Astrophysics Data System (ADS)

Kenyon, J. S.; Smirnov, O. M.; Grobler, T. L.; Perkins, S. J.

2018-05-01

It has recently been shown that radio interferometric gain calibration can be expressed succinctly in the language of complex optimisation. In addition to providing an elegant framework for further development, it exposes properties of the calibration problem which can be exploited to accelerate traditional non-linear least squares solvers such as Gauss-Newton and Levenberg-Marquardt. We extend existing derivations to chains of Jones terms: products of several gains which model different aberrant effects. In doing so, we find that the useful properties found in the single term case still hold. We also develop several specialised solvers which deal with complex gains parameterised by real values. The newly developed solvers have been implemented in a Python package called CubiCal, which uses a combination of Cython, multiprocessing and shared memory to leverage the power of modern hardware. We apply CubiCal to both simulated and real data, and perform both direction-independent and direction-dependent self-calibration. Finally, we present the results of some rudimentary profiling to show that CubiCal is competitive with respect to existing calibration tools such as MeqTrees.

TheraCal LC: From Biochemical and Bioactive Properties to Clinical Applications

PubMed Central

Rabi, Tarek

2018-01-01

Background Direct pulp capping is a popular treatment modality among dentists. TheraCal LC is a calcium silicate-based material that is designed as a direct/indirect pulp capping material. The material might be very attractive for clinicians because of its ease of handling. Unlike other calcium silicate-based materials, TheraCal LC is resin-based and does not require any conditioning of the dentine surface. The material can be bonded with different types of adhesives directly after application. There has been considerable research performed on this material since its launching; however, there are no review articles that collates information and data obtained from these studies. This review discusses the various characteristics of the material with the aim of establishing a better understanding for its clinical use. Methods A search was conducted using search engines (PubMed and Cochrane databases) in addition to reference mining of the articles that was used to locate other papers. The process of searching for the relevant studies was performed using the keywords pulp protection, pulp capping, TheraCal, and calcium silicates. Only articles in English published in peer-reviewed journals were included in the review. Conclusion This review underlines the fact that further in vitro and in vivo studies are required before TheraCal LC can be used as a direct pulp capping material. PMID:29785184

Navy CALS Vision. Draft 2.0. Volume 25

DOT National Transportation Integrated Search

1990-10-01

Computer-aided Acquisition and Logistic Support (CALS) is a joint initiative between industry and the Department of Defense (DoD) that is targeted at: (1) Improving designs for weapon systems; (2) Reducing both acquisition and logistic support costs ...

Medi-Cal Hospital Contracting—Did It Achieve Its Legislative Objectives?

PubMed Central

Brown, E. Richard; Price, Walter T.; Cousineau, Michael R.

1985-01-01

The 1982 Medi-Cal reforms and reductions established selective contracting with hospitals for inpatient care of Medi-Cal beneficiaries. The legislation established a special negotiator and criteria to be used in selecting contract hospitals. We report the findings of a study that analyzed the characteristics of contract and noncontract hospitals in Los Angeles County to assess how well these criteria were reflected in the outcome of the contracting process. We examine issues of beneficiary access to general inpatient care and to specialized services, the efficiency of contract hospitals compared with noncontract ones and quality-related issues. PMID:3898595

CTN summary of DSREDS, EDCARS, EDMICS CALS readiness testing. [Computer-aided Acquisition and Logistic Support (CALS) CALS Test Network (CTN), Digital Storage Retrieval Eng. Data System (DSREDS), Eng. Data Computer Assisted Retrieval System (EDCARS), Eng. Data Management Information and Control System (EDMICS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitschkowetz, N.; Vickers, D.L.

This report provides a summary of the Computer-aided Acquisition and Logistic Support (CALS) Test Network (CTN) Laboratory Acceptance Test (LAT) and User Application Test (UAT) activities undertaken to evaluate the CALS capabilities being implemented as part of the Department of Defense (DOD) engineering repositories. Although the individual testing activities provided detailed reports for each repository, a synthesis of the results, conclusions, and recommendations is offered to provide a more concise presentation of the issues and the strategies, as viewed from the CTN perspective.

A Simple Acronym for Doing Calculus: CAL

ERIC Educational Resources Information Center

Hathaway, Richard J.

2008-01-01

An acronym is presented that provides students a potentially useful, unifying view of the major topics covered in an elementary calculus sequence. The acronym (CAL) is based on viewing the calculus procedure for solving a calculus problem P* in three steps: (1) recognizing that the problem cannot be solved using simple (non-calculus) techniques;…

Evaluation of CalMHSA Student Mental Health Online Resources

PubMed Central

Sontag-Padilla, Lisa; Kase, Courtney Ann; Woodbridge, Michelle W.; Stein, Bradley D.

2016-01-01

Abstract Analysis of visitors to CalMHSA-funded student mental health websites shows that visitors at educational institutions comprised the largest audience segment and promotional campaigns likely increased traffic. PMID:28083438

Spatial Databases for CalVO Volcanoes: Current Status and Future Directions

NASA Astrophysics Data System (ADS)

Ramsey, D. W.

2013-12-01

The U.S. Geological Survey (USGS) California Volcano Observatory (CalVO) aims to advance scientific understanding of volcanic processes and to lessen harmful impacts of volcanic activity in California and Nevada. Within CalVO's area of responsibility, ten volcanoes or volcanic centers have been identified by a national volcanic threat assessment in support of developing the U.S. National Volcano Early Warning System (NVEWS) as posing moderate, high, or very high threats to surrounding communities based on their recent eruptive histories and their proximity to vulnerable people, property, and infrastructure. To better understand the extent of potential hazards at these and other volcanoes and volcanic centers, the USGS Volcano Science Center (VSC) is continually compiling spatial databases of volcano information, including: geologic mapping, hazards assessment maps, locations of geochemical and geochronological samples, and the distribution of volcanic vents. This digital mapping effort has been ongoing for over 15 years and early databases are being converted to match recent datasets compiled with new data models designed for use in: 1) generating hazard zones, 2) evaluating risk to population and infrastructure, 3) numerical hazard modeling, and 4) display and query on the CalVO as well as other VSC and USGS websites. In these capacities, spatial databases of CalVO volcanoes and their derivative map products provide an integrated and readily accessible framework of VSC hazards science to colleagues, emergency managers, and the general public.

M2 .50-cal. Multishot Capabilities at the US Army Research Laboratory

DTIC Science & Technology

2015-09-01

a platform was designed to simulate the 2-round burst of the M2 .50-caliber Browning machine gun (BMG). The 2-round-burst cyclic rate was achieved...ARL-TN-0694 ● SEP 2015 US Army Research Laboratory M2 .50-cal. Multishot Capabilities at the US Army Research Laboratory by...longer needed. Do not return it to the originator. ARL-TN-0694 ● SEP 2015 US Army Research Laboratory M2 .50-cal. Multishot

CAMPARE and Cal-Bridge: Two Institutional Networks Increasing Diversity in Astronomy

NASA Astrophysics Data System (ADS)

Rudolph, Alexander L.; Impey, Chris David; Phillips, Cynthia B.; Povich, Matthew S.; Prather, Edward E.; Smecker-Hane, Tammy A.

2015-01-01

We describe two programs, CAMPARE and Cal-Bridge, with the common mission of increasing participation of groups traditionally underrepresented in astronomy, particularly underrepresented minorities and women, through summer research opportunities, in the case of CAMPARE, scholarships in the case of Cal-Bridge, and significant mentoring in both programs, leading to an increase in their numbers successfully pursuing a PhD in the field.CAMPARE is an innovative REU-like summer research program, currently in its sixth year, comprising a network of comprehensive universities and community colleges in Southern California and Arizona (most of which are minority serving institutions), and ten major research institutions (University of Arizona Steward Observatory, the SETI Institute, JPL, Caltech, and the five Southern California UC campuses, UCLA, UCI, UCSD, UCR, and UCSB).In its first five summers, CAMPARE sent a total of 49 students from 10 different CSU and community college campuses to 5 research sites of the program. Of these 49 participants, 25 are women and 24 are men; 22 are Hispanic, 4 are African American, and 1 is Native American, including 6 female Hispanic and 2 female African-American participants. Twenty-one (21) CAMPARE participants have graduated from college, and more than half (11) have attended or are attending a graduate program, including 8 enrolled in PhD or Master's-to-PhD programs. Over twenty CAMPARE students have presented at the AAS and other national meetings.The Cal-Bridge program is a diverse network of higher education institutions in Southern California, including 5 UC campuses, 8 CSU campuses, and 7 community colleges dedicated to the goal of increasing the number of underrepresented minority and female students attending graduate school in astronomy or related fields. We have recently selected our inaugural group of five 2014 Cal-Bridge Scholars, including four women (two Hispanic and one part Native American), and one Hispanic man

CAMPARE and Cal-Bridge: Two Institutional Networks Increasing Diversity in Astronomy

NASA Astrophysics Data System (ADS)

Rudolph, Alexander L.; Impey, Chris David; Phillips, Cynthia B.; Povich, Matthew S.; Prather, Edward E.; Smecker-Hane, Tammy A.

2015-01-01

We describe two programs, CAMPARE and Cal-Bridge, with the common mission of increasing participation of groups traditionally underrepresented in astronomy, particularly underrepresented minorities and women, through summer research opportunities, in the case of CAMPARE, scholarships in the case of Cal-Bridge, and significant mentoring in both programs, leading to an increase in their numbers successfully pursuing a PhD in the field.CAMPARE is an innovative REU-like summer research program, currently in its sixth year, comprising a network of comprehensive universities and community colleges in Southern California and Arizona (most of which are minority serving institutions), and ten major research institutions (University of Arizona Steward Observatory, the SETI Institute, JPL, Caltech, and the five Southern California UC campuses, UCLA, UCI, UCSD, UCR, and UCSB).In its first five summers, CAMPARE sent a total of 49 students from 10 different CSU and community college campuses to 5 research sites of the program. Of these 49 participants, 25 are women and 24 are men; 22 are Hispanic, 4 are African American, and 1 is Native American, including 6 female Hispanic and 2 female African-American participants. Twenty-one (21) CAMPARE participants have graduated from college, and more than half (11) have attended or are attending a graduate program, including 8 enrolled in PhD or Master's-to-PhD programs. Over twenty CAMPARE students have presented at the AAS and other national meetings.The Cal-Bridge program is a diverse network of higher education institutions in Southern California, including 5 UC campuses, 8 CSU campuses, and 7 community colleges dedicated to the goal of increasing the number of underrepresented minority and female students attending graduate school in astronomy or related fields. We have recently selected our inaugural group of five 2014 Cal-Bridge Scholars, including four women (two Hispanic and one part Native American), and one Hispanic man

Paleoseismic investigations at the Cal thrust fault, Mendoza, Argentina

NASA Astrophysics Data System (ADS)

Salomon, Eric; Schmidt, Silke; Hetzel, Ralf; Mingorance, Francisco

2010-05-01

Along the active mountain front of the Andean Precordillera between 30°S and 34°S in western Argentina several earthquakes occurred in recent times, including a 7.0 Ms event in 1861 which destroyed the city of Mendoza and killed two thirds of its population. The 1861 event and two other earthquakes (Ms = 5.7 in 1929 and Ms = 5.6 in 1967) were generated on the Cal thrust fault, which extends over a distance of 31 km north-south and runs straight through the center of Mendoza. In the city, which has now more than 1 million inhabitants, the fault forms a 3-m-high fault scarp. Although the Cal thrust fault poses a serious seismic hazard, the paleoseismologic history of this fault and its long-term slip rate remains largely unknown (Mingorance, 2006). We present the first results of an ongoing paleoseismologic study of the Cal thrust at a site located 5 km north of Mendoza. Here, the fault offsets Late Holocene alluvial fan sediments by 2.5 m vertically and exhibits a well developed fault scarp. A 15-m-long and 2-3-m-deep trench across the scarp reveals three east-vergent folds that we interpret to have formed during three earthquakes. Successive retrodeformation of the two youngest folds suggests that the most recent event (presumably the 1861 earthquake) caused ~1.1 m of vertical offset and ~1.8 m of horizontal shortening. For the penultimate event we obtain a vertical offset of ~0.7 m and a horizontal shortening of ~1.9 m. A vertical displacement of ~0.7 m observed on a steeply west-dipping fault may be associated with an older event. The cumulative vertical offset of 2.5 m for the three inferred events is in excellent agreement with the height of the scarp. Based on the retrodeformation of the trench deposits the fault plane dips ~25° to the west. In the deepest part of the trench evidence for even older seismic events is preserved beneath an angular unconformity that was formed during a period of erosion and pre-dates the present-day scarp. Dating of samples to

CalTOX (registered trademark), A multimedia total exposure model spreadsheet user's guide. Version 4.0(Beta)

DOE Office of Scientific and Technical Information (OSTI.GOV)

McKone, T.E.; Enoch, K.G.

2002-08-01

CalTOX has been developed as a set of spreadsheet models and spreadsheet data sets to assist in assessing human exposures from continuous releases to multiple environmental media, i.e. air, soil, and water. It has also been used for waste classification and for setting soil clean-up levels at uncontrolled hazardous wastes sites. The modeling components of CalTOX include a multimedia transport and transformation model, multi-pathway exposure scenario models, and add-ins to quantify and evaluate uncertainty and variability. All parameter values used as inputs to CalTOX are distributions, described in terms of mean values and a coefficient of variation, rather than asmore » point estimates or plausible upper values such as most other models employ. This probabilistic approach allows both sensitivity and uncertainty analyses to be directly incorporated into the model operation. This manual provides CalTOX users with a brief overview of the CalTOX spreadsheet model and provides instructions for using the spreadsheet to make deterministic and probabilistic calculations of source-dose-risk relationships.« less

Delayed deglaciation or extreme Arctic conditions 21-16 cal. kyr at southeastern Laurentide Ice Sheet margin?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peteet, D. M.; Beh, M.; Orr, C.

The conventionally accepted ages of the Last Glacial Maximum (LGM) retreat of the southeastern Laurentide Ice Sheet (LIS) are 26–21 cal. kyr (derived from bulk-sediment radiocarbon ages) and 28–23 cal. kyr (varve estimates). By utilizing accelerator mass spectrometry (AMS) 14C dating of earliest macrofossils in 13 lake/bog inorganic clays, we find that vegetation first appeared on the landscape at 16–15 cal. kyr, suggesting ice had not retreated until that time. The gap between previous age estimates and ours is significant and has large implications for our understanding of ocean-atmosphere linkages. Older ages imply extreme Arctic conditions for 9–5 cal kyr;more » a landscape with no ice, yet no deposition in lakes. Also, our new AMS chronology of LIS retreat is consistent with marine evidence of deglaciation from the N. Atlantic, showing significant freshwater input and sea level rise only after 19 cal kyr with a cold meltwater lid, perhaps delaying ice melt.« less

Delayed deglaciation or extreme Arctic conditions 21-16 cal. kyr at southeastern Laurentide Ice Sheet margin?

DOE PAGES

Peteet, D. M.; Beh, M.; Orr, C.; ...

2012-06-15

The conventionally accepted ages of the Last Glacial Maximum (LGM) retreat of the southeastern Laurentide Ice Sheet (LIS) are 26–21 cal. kyr (derived from bulk-sediment radiocarbon ages) and 28–23 cal. kyr (varve estimates). By utilizing accelerator mass spectrometry (AMS) 14C dating of earliest macrofossils in 13 lake/bog inorganic clays, we find that vegetation first appeared on the landscape at 16–15 cal. kyr, suggesting ice had not retreated until that time. The gap between previous age estimates and ours is significant and has large implications for our understanding of ocean-atmosphere linkages. Older ages imply extreme Arctic conditions for 9–5 cal kyr;more » a landscape with no ice, yet no deposition in lakes. Also, our new AMS chronology of LIS retreat is consistent with marine evidence of deglaciation from the N. Atlantic, showing significant freshwater input and sea level rise only after 19 cal kyr with a cold meltwater lid, perhaps delaying ice melt.« less

Hot deformation behaviors and processing maps of B{sub 4}C/Al6061 neutron absorber composites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yu-Li

In this study, the hot deformation behaviors of 30 wt.% B{sub 4}C/Al6061 neutron absorber composites (NACs) have been investigated by conducting isothermal compression tests at temperatures ranging from 653 K to 803 K and strain rates from 0.01 to 10 s{sup −1}. It was found that, during hot compression, the B{sub 4}C/Al6061 NACs exhibited a steady flow characteristic which can be expressed by the Zener-Hollomon parameter as a hyperbolic-sine function of flow stress. High average activation energy (185.62 kJ/mol) of B{sub 4}C/Al6061 NACs is noted in current study owing to the high content of B{sub 4}C particle. The optimum hotmore » working conditions for B{sub 4}C/Al6061 NACs are found to be 760–803 K/0.01–0.05 s{sup −1} based on processing map and microstructure evolution. Typical material instabilities are thought to be attributed to void formation, adiabatic shear bands (ASB), particle debonding, and matrix cracking. Finally, the effect of the plastic deformation zones (PDZs) on the microstructure evolution in this 30 wt.% B{sub 4}C/Al6061 composite is found to be very important. - Highlights: •The hot deformation behavior of the 30 wt.% B{sub 4}C/Al6061 NACs was first analyzed. •The 3D efficiency map and the instability map are developed. •The optimum hot working conditions were identified and validated by SEM and TEM. •The hot deformation schematic diagram of 30 wt.% B{sub 4}C/Al6061 NACs is developed.« less

The challenge of estimating the SWOT signal and error spectra over the Ocean and its applications to CalVal and state estimation problems

NASA Astrophysics Data System (ADS)

Ubelmann, C.; Gerald, D.

2016-12-01

The SWOT data validation will be a first challenge after launch, as the nature of the measurement, in particular the two-dimensionality at short spatial scales, is new in altimetry. If the comparison with independent observations may be locally possible, a validation of the full signal and error spectrum will be challenging. However, some recent analyses in simulations have shown the possibility to separate the geophysical signals from the spatially coherent instrumental errors in the spectral space, through cross-spectral analysis. These results suggest that rapidly after launch, the instrument error canl be spectrally separated providing some validations and insights on the Ocean energy spectrum, as well as optimal calibrations. Beyond CalVal, such spectral computations will be also essential for producing high-level Ocean estimates (two and three dimensional Ocean state reconstructions).

78 FR 1252 - CalAmp Wireless Networks Corporation (CWNC), Satellite Products Division, Including On-Site...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

... Select Staffing, Oxnard, CA; CalAmp Wireless Networks Corporation (CWNC), Including On- Site Leased... Division, including on-site leased workers from Select Staffing, Oxnard, California (TA-W-80,399). The...-site leased workers from Select Staffing, Oxnard, California (TA-W-80,399) and CalAmp Wireless Networks...

Resistance of human plasmacytoid dendritic CAL-1 cells to infection with lymphocytic choriomeningitis virus (LCMV) is caused by restricted virus cell entry, which is overcome by contact of CAL-1 cells with LCMV-infected cells.

PubMed

Iwasaki, Masaharu; Sharma, Siddhartha M; Marro, Brett S; de la Torre, Juan C

2017-11-01

Plasmacytoid dendritic cells (pDCs), a main source of type I interferon in response to viral infection, are an early cell target during lymphocytic choriomeningitis virus (LCMV) infection, which has been associated with the LCMV's ability to establish chronic infections. Human blood-derived pDCs have been reported to be refractory to ex vivo LCMV infection. In the present study we show that human pDC CAL-1 cells are refractory to infection with cell-free LCMV, but highly susceptible to infection with recombinant LCMVs carrying the surface glycoprotein of VSV, indicating that LCMV infection of CAL-1 cells is restricted at the cell entry step. Co-culture of uninfected CAL-1 cells with LCMV-infected HEK293 cells enabled LCMV to infect CAL-1 cells. This cell-to-cell spread required direct cell-cell contact and did not involve exosome pathway. Our findings indicate the presence of a novel entry pathway utilized by LCMV to infect pDC. Copyright © 2017. Published by Elsevier Inc.

Cal Council: A Story of Continuity and Change

ERIC Educational Resources Information Center

Brunetti, Gerald J.

2015-01-01

Gerald Brunetti served as President of the California Council on the Education of Teachers (Cal Council or CCET) from 1992 to 1994. This article describes the author's involvement with the CCET beginning in 1979, and covers the details of accomplishments throughout his presidency, such as the development of "CCNews," mail balloting, and…

CALS Database Usage and Analysis Tool Study

DTIC Science & Technology

1991-09-01

inference aggregation and cardinality aggregation as two distinct aspects of the aggregation problem. The paper develops the concept of a semantic...aggregation, cardinality aggregation I " CALS Database Usage Analysis Tool Study * Bibliography * Page 7 i NIDX - An Expert System for Real-Time...1989 IEEE Symposium on Research in Security and Privacy, Oakland, CA, May 1989. [21 Baur, D.S.; Eichelman, F.R. 1I; Herrera , R.M.; Irgon, A.E

CalWater 2 - Precipitation, Aerosols, and Pacific Atmospheric Rivers Experiment

NASA Astrophysics Data System (ADS)

Spackman, Ryan; Ralph, Marty; Prather, Kim; Cayan, Dan; DeMott, Paul; Dettinger, Mike; Fairall, Chris; Leung, Ruby; Rosenfeld, Daniel; Rutledge, Steven; Waliser, Duane; White, Allen

2014-05-01

Emerging research has identified two phenomena that play key roles in the variability of the water supply and the incidence of extreme precipitation events along the West Coast of the United States. These phenomena include the role of (1) atmospheric rivers (ARs) in delivering much of the precipitation associated with major storms along the U.S. West Coast, and (2) aerosols—from local sources as well as those transported from remote continents—and their modulating effects on western U.S. precipitation. A better understanding of these processes is needed to reduce uncertainties in weather predictions and climate projections of extreme precipitation and its effects, including the provision of beneficial water supply. This presentation summarizes science gaps associated with (1) the evolution and structure of ARs including cloud and precipitation processes and air-sea interaction, and (2) aerosol interaction with ARs and the impact on precipitation, including locally-generated aerosol effects on orographic precipitation along the U.S. West Coast. Observations are proposed for multiple winter seasons as part of a 5-year broad interagency vision referred to as CalWater 2 to address these science gaps (http://esrl.noaa.gov/psd/calwater). In the near term, a science investigation is being planned including a targeted set of aircraft and ship-based measurements and associated evaluation of data in near-shore regions of California and in the eastern Pacific for an intensive observing period between January 2015 and March 2015. DOE's Atmospheric Radiation Measurement (ARM) program and NOAA are coordinating on deployment of airborne and ship-borne facilities for this period in a DOE-sponsored study called ACAPEX (ARM Cloud Aerosol and Precipitation Experiment) to complement CalWater 2. The motivation for this major study is based on findings that have emerged in the last few years from airborne and ground-based studies including CalWater and NOAA's HydroMeterology Testbed

78 FR 62614 - CalWind Resources, Inc. v. California Independent System Operator Corporation; Notice of Complaint

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL14-4-000] CalWind Resources, Inc. v. California Independent System Operator Corporation; Notice of Complaint Take notice that... 385.206 (2013), CalWind Resources, Inc. (Complainant) filed a formal complaint against California...

Cal/Val activities for DubaiSat-2 performance assessment

NASA Astrophysics Data System (ADS)

Bushahab, A.; Al-Mansoori, S.; Al-Suwaidi, K.; Al Matroushi, Hessa; Al-Tunaiji, E.; Al Shamsi, Meera

2014-10-01

Emirates Institution for Advanced Science and Technology (EIAST) was established by the Dubai Government in 2006. After three years of working together with Satrec Initiative (South Korea), EIAST was able to launch DubaiSat-1 on the 29th of July 2009. Building on the success of DubaiSat-1 and the roll out of the knowledge transfer program, UAE engineers were involved in almost 70% of the total build and design of DubaiSat-2. Targeting the commercial market, DubaiSat-2 was launched on the 21st of November 2013 for capturing 1-meter resolution images. The 1st Cal/Val phase was the most critical phase in the satellite life-time, where most of the initial measurements took place. This phase extended over the period of 25/11/2013 till 12/12/2013. Moreover, this phase included most of the relative calibration tasks, color balancing and band matching. 2nd Cal/Val phase included most of the debugging and the pointing accuracy calibration tests. This phase extended over the period of 11/02/2014 till 09/03/2014. This phase emphasized on the calibration of the pointing accuracy. The 3rd Cal/Val phase included fine tuning for the Gyro system to further increase the stability of the satellite and thus improve the pointing accuracy. Moreover, new techniques were implemented to the Pan-Sharpening and to the MTF compensation procedures to enhance the final product. This phase extended over the period of 04/05/2014 till 21/05/2014.

Sediment record of environmental change at Lake Lop Nur (Xinjiang, NW China) from 13.0 to 5.6 cal ka BP

NASA Astrophysics Data System (ADS)

Wang, Jingzhong; Jia, Hongjuan

2017-09-01

Lake Lop Nur is located in the eastern part of the Tarim Basin in Xinjiang, northwestern China. A 220-cm-long sediment core was collected from the center of the ear-shaped depression forming the basin and dated with AMS14C. Grain size, total organic matter (TOC), total nitrogen (TN), and TOC/TN (C/N) analyses were used to reconstruct climatic conditions from 13.0 to 5.6 cal ka BP. The results showed five main climatic stages. Zone I (13.0-11.3 cal ka BP) was a wet-dry environment, whereas Zone II (11.3-8.9 cal ka BP) consisted of a primarily wet environment. Zone III (8.9-7.7 cal ka BP) was subdivided into Zone IIIa (8.9-8.2 cal ka BP) that indicated lake constriction and dry climate, and Zone IIIb (8.2-7.7 cal ka BP) in which the proxies indicated wet conditions. In Zone IV (7.7-6.6 cal ka BP), the climate presented a bit wet conditions. In Zone V (6.6-5.6 cal ka BP), abundant glauberite is present in the sediment and silt dominates the lithology; these results indicate the lake shrank and the overall climate was dry. Abrupt environmental events were also identified, including six dry events at 11.0, 10.5, 9.3, 8.6, 8.2, and 7.6 cal ka BP and one flood event from 7.8 to 7.7 cal ka BP in the Early-Middle Holocene.

Dryden Test Pilots 1990 - Smolka, Fullerton, Schneider, Dana, Ishmael, Smith, and McMurtry

NASA Technical Reports Server (NTRS)

1990-01-01

It was a windy afternoon on Rogers Dry Lake as the research pilots of the National Aeronautics and Space Administration's Ames-Dryden Flight Research Facility gathered for a photo shoot. It was a special day too, the 30th anniversary of the first F-104 flight by research pilot Bill Dana. To celebrate, a fly over of Building 4800, in formation, was made with Bill in a Lockheed F-104 (826), Gordon Fullerton in a Northrop T-38, and Jim Smolka in a McDonnell Douglas F/A-18 (841) on March 23, 1990. The F-18 (841), standing on the NASA ramp is a backdrop for the photo of (Left to Right) James W. (Smoke) Smolka, C. Gordon Fullerton, Edward T. (Ed) Schneider, William H. (Bill) Dana, Stephen D. (Steve) Ishmael, Rogers E. Smith, and Thomas C. (Tom) McMurtry. Smolka joined NASA Ames-Dryden Flight Research Facility in September 1985. He has been the project pilot on the F-15 Advanced Control Technology for Integrated Vehicles (ACTIVE) research and F-15 Aeronautical Research Aircraft programs. He has also flown as a pilot on the NASA B-52 launch aircraft, as a co-project pilot on the F-16XL Supersonic Laminar Flow Control aircraft and the F-18 High Angle-of-Attack Research Vehicle (HARV) aircraft. Other aircraft he has flown in research programs are the F-16, F-111, F-104 and the T-38 as support. Fullerton, joined NASA's Ames-Dryden Flight Research Facility in November 1986. He was project pilot on the NASA/Convair 990 aircraft to test space shuttle landing gear components, project pilot on the F-18 Systems Research Aircraft, and project pilot on the B-52 launch aircraft, where he was involved in six air launches of the commercially developed Pegasus space launch vehicle. Other assignments include a variety of flight research and support activities in multi-engine and high performance aircraft such as, F-15, F-111, F-14, X-29, MD-11 and DC-8. Schneider arrived at the NASA Ames-Dryden Flight Research Facility on July 5, 1982, as a Navy Liaison Officer, becoming a NASA research

Monitoring Outcomes for Los Angeles County's Pre- and Post-CalWORKS Leavers: How Are They Faring?

ERIC Educational Resources Information Center

Verma, Nandita; Hendra, Richard

The characteristics, earnings, employment experiences, and material well-being of California welfare recipients after leaving welfare were examined by comparing the postwelfare experiences of groups who exited welfare before and after institution of California's welfare reform program CalWORKs. The first group (pre-CalWORKs group) exited welfare…

CAL--ERDA program manual. [Building Design Language; LOADS, SYSTEMS, PLANT, ECONOMICS, REPORT, EXECUTIVE, CAL-ERDA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunn, B. D.; Diamond, S. C.; Bennett, G. A.

1977-10-01

A set of computer programs, called Cal-ERDA, is described that is capable of rapid and detailed analysis of energy consumption in buildings. A new user-oriented input language, named the Building Design Language (BDL), has been written to allow simplified manipulation of the many variables used to describe a building and its operation. This manual provides the user with information necessary to understand in detail the Cal-ERDA set of computer programs. The new computer programs described include: an EXECUTIVE Processor to create computer system control commands; a BDL Processor to analyze input instructions, execute computer system control commands, perform assignments andmore » data retrieval, and control the operation of the LOADS, SYSTEMS, PLANT, ECONOMICS, and REPORT programs; a LOADS analysis program that calculates peak (design) zone and hourly loads and the effect of the ambient weather conditions, the internal occupancy, lighting, and equipment within the building, as well as variations in the size, location, orientation, construction, walls, roofs, floors, fenestrations, attachments (awnings, balconies), and shape of a building; a Heating, Ventilating, and Air-Conditioning (HVAC) SYSTEMS analysis program capable of modeling the operation of HVAC components including fans, coils, economizers, humidifiers, etc.; 16 standard configurations and operated according to various temperature and humidity control schedules. A plant equipment program models the operation of boilers, chillers, electrical generation equipment (diesel or turbines), heat storage apparatus (chilled or heated water), and solar heating and/or cooling systems. An ECONOMIC analysis program calculates life-cycle costs. A REPORT program produces tables of user-selected variables and arranges them according to user-specified formats. A set of WEATHER ANALYSIS programs manipulates, summarizes and plots weather data. Libraries of weather data, schedule data, and building data were prepared.« less

Overview Of Cal-Mex 2010: US-Mexico Collaborative Project On Air Quality And Climate Change In The California-Mexico Border Region

NASA Astrophysics Data System (ADS)

Molina, L. T.; Cal-Mex Science Team

2010-12-01

The composition of the atmosphere over the US-Mexico border region is affected by cross-border transport of emissions in both directions. Air quality issues in the California-Mexico (Cal-Mex) border are associated with air masses originating in the portion of the border region adjacent to California, which includes two of the sister city pairs (Tijuana-San Diego and Mexicali-Calexico) that have the most severe air pollution problems, posing a serious health threat to their inhabitants as well as affecting ecosystem viability and regional climate for large downwind distances. During May-June 2010, an intensive field study was undertaken by US-Mexico collaborative teams to characterize the major sources of primary and secondary particulate matter and precursor gases in the California-Mexico (Cal-Mex) border region, their transport and transformation, and the impact of these emissions on regional air quality and climate. The ground-based measurements included a central fixed site located in Tijuana that housed state-of-the-science instruments to measure gases, aerosols, radiation and meteorological parameters; a mobile eddy covariance laboratory that measured surface-atmosphere exchange fluxes of carbon dioxide, nitrogen oxides, and particle number; several mobile units for criteria pollutants and meteorological parameters; and measurements of fine particles and trace gases at the border crossing areas. Preliminary results from the field study will be presented. Cal-Mex Science Team includes: Molina Center for Energy and the Environment, Texas A & M University, Scripps Institution of Oceanography/University of California at San Diego, Virginia Tech, San Diego State University, National University of Mexico, National Institute of Ecology/Mexican Ministry of the Environment, University of the State of Morelos, LT Consulting Group, University of Baja California (Mexicali, Tijuana, Ensenada, Valle de Las Palmas campuses), Secretary of the Environment of Baja California

Vibrio parahaemolyticus CalR down regulates the thermostable direct hemolysin (TDH) gene transcription and thereby inhibits hemolytic activity.

PubMed

Zhang, Yiquan; Zhang, Ying; Gao, He; Zhang, Lingyu; Yin, Zhe; Huang, Xinxiang; Zhou, Dongsheng; Yang, Huiying; Yang, Wenhui; Wang, Li

2017-05-20

TDH, encoded by tdh gene, is a major virulent determinant of V. parahaemolyticus that controls various biological activities, such as hemolytic activity, cytotoxicity, and enterotoxicity. The hemolytic activity on Wagatsuma agar ascribed to TDH is called Kanagawa phenomenon (KP). All KP positive strains contain tdh1 and tdh2 genes, but tdh2 is predominantly responsible for KP. CalR is a regulatory protein that was originally identified as a repressor of swarming motility and T3SS1 gene expression in V. parahaemolyticus. In the present study, the regulation of tdh2 by CalR was investigated using a set of experiments including qRT-PCR, primer extension, LacZ fusion, hemolytic phenotype, EMSA, and DNase I footprinting assays. The results showed that His-CalR protected a single region from 224bp to 318bp upstream of tdh2 against DNase I digestion, and a transcriptional start site located at 42bp upstream of tdh2 was detected and its transcribed activity was inhibited by CalR. Moreover, the KP test results showed that the hemolytic activity of V. parahaemolyticus is also under negative control of CalR. The data demonstrated that CalR is a repressor of the tdh2 transcription and thereby inhibits the hemolytic activity of V. parahaemolyticus. Copyright © 2017. Published by Elsevier B.V.

NATAL-74; Towards a Common Programming Language for CAL.

ERIC Educational Resources Information Center

Brahan, J. W.; Colpitts, B. A.

NATAL-74 is a programing language designed for Canadian computer aided learning (CAL) programs. The language has two fundamental elements: the UNIT provides the interface between the student and the subject matter, and the PROCEDURE element embodies teaching strategy. Desirable features of several programing languages have been adapted to cope…

Impact of CALS on Electronic Publishing Systems and Users.

ERIC Educational Resources Information Center

Beazley, William G.

1990-01-01

The U.S. Department of Defense has begun using its buying power to enforce standards on the vendors and contractors of automatic data processing hardware and software. An example of this, the Computer-Aided Acquisition and Logistic Support (CALS) program, is described, and how it will affect electronic publishing systems is discussed. (five…

Wave Energy Prize - 1/50th Testing - CalWave

DOE Data Explorer

Wesley Scharmen

2016-01-15

This submission of data includes all the 1/50th scale testing data completed on the Wave Energy Prize for the CalWave team, and includes: 1/50th test data (raw & processed) 1/50th test data video and pictures 1/50th Test plans and testing documents SSTF_Submission (summarized results)

CalWater 2 - Precipitation, Aerosols, and Pacific Atmospheric Rivers Experiment

NASA Astrophysics Data System (ADS)

Spackman, J. R.; Ralph, F. M.; Prather, K. A.; Cayan, D. R.; DeMott, P. J.; Dettinger, M. D.; Fairall, C. W.; Leung, L. R.; Rosenfeld, D.; Rutledge, S. A.; Waliser, D. E.; White, A. B.

2014-12-01

Emerging research has identified two phenomena that play key roles in the variability of the water supply and the incidence of extreme precipitation events along the West Coast of the United States. These phenomena include the role of (1) atmospheric rivers (ARs) in delivering much of the precipitation associated with major storms along the U.S. West Coast, and (2) aerosols—from local sources as well as those transported from remote continents—and their modulating effects on western U.S. precipitation. A better understanding of these processes is needed to reduce uncertainties in weather predictions and climate projections of extreme precipitation and its effects, including the provision of beneficial water supply. This presentation summarizes the science objectives and strategies to address gaps associated with (1) the evolution and structure of ARs including cloud and precipitation processes and air-sea interaction, and (2) aerosol interaction with ARs and the impact on precipitation, including locally-generated aerosol effects on orographic precipitation along the U.S. West Coast. Observations are proposed for multiple winter seasons as part of a 5-year broad interagency vision referred to as CalWater 2 to address these science gaps (http://esrl.noaa.gov/psd/calwater). In January-February 2015, a field campaign has been planned consisting of a targeted set of aircraft and ship-based measurements and associated evaluation of data in near-shore regions of California and in the eastern Pacific. In close coordination with NOAA, DOE's Atmospheric Radiation Measurement (ARM) program is also contributing air and shipborne facilities for ACAPEX (ARM Cloud Aerosol and Precipitation Experiment), a DOE-sponsored study complementing CalWater 2. Ground-based measurements from NOAA's HydroMeteorological Testbed (HMT) network in California and aerosol chemical instrumentation at Bodega Bay, California have been designed to add important near surface-level context for the

A Comparison of CAL with a Conventional Method of Delivery of Cell Biology to Undergraduate Nursing Students Using an Experimental Design.

ERIC Educational Resources Information Center

Wharrad, Heather J.; Kent, Christine; Allcock, Nick; Wood, Barry

2001-01-01

In study 1, 12 nursing students attended slide lectures on cell biology; 13 used interactive computer-assisted learning (CAL). Study 2 surveyed 38 students who used CAL to study immunology. Students preferred CAL and felt confident in their grasp of the material, even without the presence of lecturers to answer questions. (Contains 16 references.)…

Retooling CalEnviroScreen: Cumulative Pollution Burden and Race-Based Environmental Health Vulnerabilities in California.

PubMed

Liévanos, Raoul S

2018-04-16

The California Community Environmental Health Screening Tool (CalEnviroScreen) advances research and policy pertaining to environmental health vulnerability. However, CalEnviroScreen departs from its historical foundations and comparable screening tools by no longer considering racial status as an indicator of environmental health vulnerability and predictor of cumulative pollution burden. This study used conceptual frameworks and analytical techniques from environmental health and inequality literature to address the limitations of CalEnviroScreen, especially its inattention to race-based environmental health vulnerabilities. It developed an adjusted measure of cumulative pollution burden from the CalEnviroScreen 2.0 data that facilitates multivariate analyses of the effect of neighborhood racial composition on cumulative pollution burden, net of other indicators of population vulnerability, traffic density, industrial zoning, and local and regional clustering of pollution burden. Principal component analyses produced three new measures of population vulnerability, including Latina/o cumulative disadvantage that represents the spatial concentration of Latinas/os, economic disadvantage, limited English-speaking ability, and health vulnerability. Spatial error regression analyses demonstrated that concentrations of Latinas/os, followed by Latina/o cumulative disadvantage, are the strongest demographic determinants of adjusted cumulative pollution burden. Findings have implications for research and policy pertaining to cumulative impacts and race-based environmental health vulnerabilities within and beyond California.

Retooling CalEnviroScreen: Cumulative Pollution Burden and Race-Based Environmental Health Vulnerabilities in California

PubMed Central

2018-01-01

The California Community Environmental Health Screening Tool (CalEnviroScreen) advances research and policy pertaining to environmental health vulnerability. However, CalEnviroScreen departs from its historical foundations and comparable screening tools by no longer considering racial status as an indicator of environmental health vulnerability and predictor of cumulative pollution burden. This study used conceptual frameworks and analytical techniques from environmental health and inequality literature to address the limitations of CalEnviroScreen, especially its inattention to race-based environmental health vulnerabilities. It developed an adjusted measure of cumulative pollution burden from the CalEnviroScreen 2.0 data that facilitates multivariate analyses of the effect of neighborhood racial composition on cumulative pollution burden, net of other indicators of population vulnerability, traffic density, industrial zoning, and local and regional clustering of pollution burden. Principal component analyses produced three new measures of population vulnerability, including Latina/o cumulative disadvantage that represents the spatial concentration of Latinas/os, economic disadvantage, limited English-speaking ability, and health vulnerability. Spatial error regression analyses demonstrated that concentrations of Latinas/os, followed by Latina/o cumulative disadvantage, are the strongest demographic determinants of adjusted cumulative pollution burden. Findings have implications for research and policy pertaining to cumulative impacts and race-based environmental health vulnerabilities within and beyond California. PMID:29659481

The Kunming CalFit study: modeling dietary behavioral patterns using smartphone data.

PubMed

Seto, Edmund; Hua, Jenna; Wu, Lemuel; Bestick, Aaron; Shia, Victor; Eom, Sue; Han, Jay; Wang, May; Li, Yan

2014-01-01

Human behavioral interventions aimed at improving health can benefit from objective wearable sensor data and mathematical models. Smartphone-based sensing is particularly practical for monitoring behavioral patterns because smartphones are fairly common, are carried by individuals throughout their daily lives, offer a variety of sensing modalities, and can facilitate various forms of user feedback for intervention studies. We describe our findings from a smartphone-based study, in which an Android-based application we developed called CalFit was used to collect information related to young adults' dietary behaviors. In addition to monitoring dietary patterns, we were interested in understanding contextual factors related to when and where an individual eats, as well as how their dietary intake relates to physical activity (which creates energy demand) and psychosocial stress. 12 participants were asked to use CalFit to record videos of their meals over two 1-week periods, which were translated into nutrient intake by trained dietitians. During this same period, triaxial accelerometry was used to assess each subject's energy expenditure, and GPS was used to record time-location patterns. Ecological momentary assessment was also used to prompt subjects to respond to questions on their phone about their psychological state. The GPS data were processed through a web service we developed called Foodscoremap that is based on the Google Places API to characterize food environments that subjects were exposed to, which may explain and influence dietary patterns. Furthermore, we describe a modeling framework that incorporates all of these information to dynamically infer behavioral patterns that may be used for future intervention studies.

Plans: 3'/50 Cal. Gun Platform, Boat Deck House Top & ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Plans: 3'/50 Cal. Gun Platform, Boat Deck House Top & Fidley Top, Boat Deck, Radar Platform Lower, Pilot House Top, Navigation Bridge, Upper Bridge Deck, Poop Deck, Cargo Deck, Motor Boat Platform, Bridge Deck, Forecastle Deck, Upper Deck - Taluga, Suisun Bay Reserve Fleet, Benicia, Solano County, CA

Investigating Atmospheric Rivers using GPS TPW during CalWater 2015

NASA Astrophysics Data System (ADS)

Almanza, V.; Foster, J. H.; Businger, S.

2015-12-01

Ship-based Global Positioning System (GPS) receivers have been successful in obtaining millimeter accuracy total precipitable water (TPW). We apply this technique with a field experiment using a GPS meteorology system installed on board the R/V Ronald Brown during the CalWater 2015 project. The goal of CalWater is to monitor atmospheric river (AR) events over the Eastern Pacific Ocean and improve forecasting of the extreme precipitation events they can produce. During the 30-day cruise, TPW derived from radiosonde balloons released from the Ron Brown are used to verify the accuracy of shipboard GPS TPW. The results suggest that ship-based GPS TPW offers a cost-effective approach for acquiring accurate real-time meteorological observations of TPW in AR's over remote oceans, as well as near the coastlines where satellites algorithms have limited accuracy. The results have implications for augmenting operational observing networks to improve weather prediction and nowcasting of ARs, thereby supporting hazard response and mitigation efforts associated with coastal flooding events.

CalR is required for the expression of T6SS2 and the adhesion of Vibrio parahaemolyticus to HeLa cells.

PubMed

Zhang, Lingyu; Osei-Adjei, George; Zhang, Ying; Gao, He; Yang, Wenhui; Zhou, Dongsheng; Huang, Xinxiang; Yang, Huiying; Zhang, Yiquan

2017-08-01

Vibrio parahaemolyticus expresses one major virulence determinant T6SS2, which is constituted into three putative operons, i.e., VPA1027-1024, VPA1043-1028, and VPA1044-1046. CalR, a LysR-type transcriptional regulator, was originally identified as a repressor of the swarming motility and T3SS1 gene expression. As shown in this study, CalR binds to the promoter-proximal region of each of the three operons to activate their transcription, and moreover, CalR activates the adhesion of V. parahaemolyticus to HeLa cells. In addition, competitive EMSAs demonstrated that CalR acts as an antagonist of H-NS in V. parahaemolyticus. Collectively, these studies confirmed a new physiological role for CalR in V. parahaemolyticus.

OSD CALS Architecture Master Plan Study. Concept Paper. Indexing. Volume 30

DOT National Transportation Integrated Search

1989-06-01

An index identifies and reference information which is exchanged between multiple users and systems. The increased automation that will take place as CALS evolves will dictate an increased use of indexes for the successful exchange of information. Th...

Computer Augmented Lectures (CAL): A New Teaching Technique for Chemistry.

ERIC Educational Resources Information Center

Masten, F. A.; And Others

A new technique described as computer augmented lectures (CAL) is being used at the University of Texas at Austin. It involves the integration of on-line, interactive, time sharing computer terminals and theater size video projectors for large screen display. This paper covers the basic concept, pedagogical techniques, experiments conducted,…

Cal Poly Space Project G-279

NASA Technical Reports Server (NTRS)

Farley, David R.

1987-01-01

The Cal Poly Space Project is an effort on the part of several highly motivated students to deploy a space canister which will examine the effects of microgravity on electroplating and immiscible metals. The experiments will be controlled and monitored by a specialized triple redundancy system developed to defer the possible electronic errors due to uncontrollable factors such as photons from the Sun. With the finalization of the payload design and the near completion of the data control system, the integration phase of the project is anticipated to be completed and the project ready for launching by early 1987. It is hoped that the experiments will lead to new insights in space research and also prove profitable to industry.

A new Late Weichselian and Holocene marine chronology for the western Svalbard slope 30,000-0 cal years BP

NASA Astrophysics Data System (ADS)

Jessen, Simon P.; Rasmussen, Tine L.; Nielsen, Tove; Solheim, Anders

2010-05-01

Data have been compiled from eleven sediment cores from 76° to 80°N on the western Svalbard slope. The cores are from water depths between 630 and 1880 m and show clear similarities in lithology and magnetic susceptibility. All cores penetrated into mass transported sediments from glacigenic debris flow events and turbidity flow events. The mass transport probably occurred when the ice reached the shelf edge. The deposits date between 24,080 ± 150 and 23,550 ± 185 calibrated (cal) years BP. The records also include laminated, fine grained sediments interpreted as deposits from sediment-laden meltwater plumes dated between 14,780 ± 220 and 14,300 ± 260 cal years BP. In Holocene sediments a diatom-rich fine grained layer dates 10,100 ± 150 to 9840 ± 200 cal years BP. The eleven cores have been stacked into one record with absolute age control from 35 AMS 14C dates. Together with oxygen isotope stratigraphy and contents of ice rafted detritus the stacked record provides a useful chronology tool for cores on the western Svalbard slope. Our study improves the age control of earlier well documented glacial events and shows that the maximum glacial state and the onset of the deglaciation both occurred 2500-3000 years earlier than previously reconstructed for the western Svalbard margin. The results indicate that during the last 30,000 years advance and retreat of the Svalbard-Barents Sea Ice Sheet was closely linked to the flow of Atlantic Water and Polar Water over the margin.

76 FR 70520 - Rovac Corp., RS Group of Companies, Inc., Rymer Foods, Inc. Stratus Services Group, Inc., Sun Cal...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

...., Rymer Foods, Inc. Stratus Services Group, Inc., Sun Cal Energy, Inc., Sun Motor International, Inc... current and accurate information concerning the securities of Sun Cal Energy, Inc. because it has not... Sun Motor International, Inc. because it has not filed any periodic reports since the period ended...

Health Promotion Interventions for Low-Income Californians Through Medi-Cal Managed Care Plans, 2012

PubMed Central

Kohatsu, Neal D.; Paciotti, Brian M.; Byrne, Jennifer V.; Kizer, Kenneth W.

2015-01-01

Introduction Prevention is the most cost-effective approach to promote population health, yet little is known about the delivery of health promotion interventions in the nation’s largest Medicaid program, Medi-Cal. The purpose of this study was to inventory health promotion interventions delivered through Medi-Cal Managed Care Plans; identify attributes of the interventions that plans judged to have the greatest impact on their members; and determine the extent to which the plans refer members to community assistance programs and sponsor health-promoting community activities. Methods The lead health educator from each managed care plan was asked to complete a 190-item online survey in January 2013; 20 of 21 managed care plans responded. Survey data on the health promotion interventions with the greatest impact were grouped according to intervention attributes and measures of effectiveness; quantitative data were analyzed using descriptive statistics. Results Health promotion interventions judged to have the greatest impact on Medi-Cal members were delivered in various ways; educational materials, one-on-one education, and group classes were delivered most frequently. Behavior change, knowledge gain, and improved disease management were cited most often as measures of effectiveness. Across all interventions, median educational hours were limited (2.4 h), and median Medi-Cal member participation was low (265 members per intervention). Most interventions with greatest impact (120 of 137 [88%]) focused on tertiary prevention. There were mixed results in referring members to community assistance programs and investing in community activities. Conclusion Managed care plans have many opportunities to more effectively deliver health promotion interventions. Establishing measurable, evidence-based, consensus standards for such programs could facilitate improved delivery of these services. PMID:26564012

Creating an open access cal/val repository via the LACO-Wiki online validation platform

NASA Astrophysics Data System (ADS)

Perger, Christoph; See, Linda; Dresel, Christopher; Weichselbaum, Juergen; Fritz, Steffen

2017-04-01

to simplify the workflows as much as possible so that the tool can be used both professionally and in an educational or non-expert context. By using the tool for validation, the user agrees to share their validation samples and therefore contribute to an open access cal/val repository. Interest in the use of LACO-Wiki for validation of national land cover or related products has already been expressed, e.g. by national stakeholders under the umbrella of the European Environment Agency (EEA), and for global products by GOFC/GOLD and the Group on Earth Observation (GEO). Thus, LACO-Wiki has the potential to become the focal point around which an international land cover validation community could be built, and could significantly advance the state-of-the-art in land cover cal/val, particularly given recent developments in opening up of the Landsat archive and the open availability of Sentinel imagery. The platform will also offer open access to crowdsourced in-situ data, for example, from the recently developed LACO-Wiki mobile smartphone app, which can be used to collect additional validation information in the field, as well as to validation data collected via its partner platform, Geo-Wiki, where an already established community of citizen scientists collect land cover and land use data for different research applications.

Playback Station #2 for Cal Net and 5-day-recorder tapes

USGS Publications Warehouse

Eaton, Jerry P.

1978-01-01

A second system (Playback Station #2) has been set up to play back Cal Net 1" tapes and 5-day-recorder 1/2" tapes. As with the first playback system (Playback Station #1) the tapes are played back on a Bell and Howell VR3700B tape deck and the records are written out on a 16-channel direct-writing Siemens "0scillomink." Separate reproduce heads, tape guides, and tape tension sensor rollers are required for playing back 111 tapes and 1/2" tapes, but changing these tape deck components is a simple task that requires only a few minutes. The discriminators, patch panels, selector switches, filters, time code translators, and signal conditioning circuits for the time code translators and for the tape-speed-compensation signal are all mounted in an equipment rack that stands beside the playback tape deck. Changing playback speeds (15/16 ips or 3 3/4 ips) or changing from Cal Net tapes to 5-day-recorder tapes requires only flipping a few switches and/or changing a few patch cables on the patch panel (in addition to changing the reproduce heads, etc., to change from 1" tape to 1/2" tape). For the Cal Net tapes, the system provides for playback of 9 data channels (680 Hz thru 3060 Hz plus 400 Hz) and 3 time signals (IRIG-E, IRIG-C, and WWVB) at both 15/16 ips (x1 speed) and 3 3/4 ips (x4 speed). Available modes of compensation (using either a 4688 Hz reference or a 3125 Hz reference) are subtractive, capstan, capstan plus subtractive, or no compensation.

Searching for evidence of curricular effect on the teaching and learning of mathematics: some insights from the LieCal project

NASA Astrophysics Data System (ADS)

Cai, Jinfa

2014-12-01

Drawing on evidence from the Longitudinal Investigation of the Effect of Curriculum on Algebra Learning (LieCal) Project, issues related to mathematics curriculum reform and student learning are discussed. The LieCal Project was designed to longitudinally investigate the impact of a reform mathematics curriculum called the Connected Mathematics Project (CMP) in the USA on teachers' teaching and students' learning. Using a three-level conceptualization of curriculum (intended, implemented, and attained), a variety of evidence from the LieCal Project is presented to show the impact of mathematics curriculum reform on teachers' teaching and students' learning. This paper synthesizes findings from the two longitudinal studies spanning 7 years of the LieCal Project both to show the kind of impact curriculum has on teachers' teaching and students' learning and to suggest powerful but feasible ways researchers can investigate curriculum effect on both teaching and learning.

17. 'BIRDSEYEVIEW, PRESIDIO OF MONTEREY, CAL., JAN. 1938.' No signature, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. 'BIRDSEYEVIEW, PRESIDIO OF MONTEREY, CAL., JAN. 1938.' No signature, photographer probably Anton C. Heidrick. This panoramic view looks west over Soldier Field from the upper floor or roof of the gymnasium. Original cool toned silver gelatin print measures 85.1 cm by 22.4 cm, flush mounted on mat board. - Presidio of Monterey, Soldier Field, Monterey, Monterey County, CA

FlowCal: A user-friendly, open source software tool for automatically converting flow cytometry data from arbitrary to calibrated units

PubMed Central

Castillo-Hair, Sebastian M.; Sexton, John T.; Landry, Brian P.; Olson, Evan J.; Igoshin, Oleg A.; Tabor, Jeffrey J.

2017-01-01

Flow cytometry is widely used to measure gene expression and other molecular biological processes with single cell resolution via fluorescent probes. Flow cytometers output data in arbitrary units (a.u.) that vary with the probe, instrument, and settings. Arbitrary units can be converted to the calibrated unit molecules of equivalent fluorophore (MEF) using commercially available calibration particles. However, there is no convenient, non-proprietary tool available to perform this calibration. Consequently, most researchers report data in a.u., limiting interpretation. Here, we report a software tool named FlowCal to overcome current limitations. FlowCal can be run using an intuitive Microsoft Excel interface, or customizable Python scripts. The software accepts Flow Cytometry Standard (FCS) files as inputs and is compatible with different calibration particles, fluorescent probes, and cell types. Additionally, FlowCal automatically gates data, calculates common statistics, and produces publication quality plots. We validate FlowCal by calibrating a.u. measurements of E. coli expressing superfolder GFP (sfGFP) collected at 10 different detector sensitivity (gain) settings to a single MEF value. Additionally, we reduce day-to-day variability in replicate E. coli sfGFP expression measurements due to instrument drift by 33%, and calibrate S. cerevisiae mVenus expression data to MEF units. Finally, we demonstrate a simple method for using FlowCal to calibrate fluorescence units across different cytometers. FlowCal should ease the quantitative analysis of flow cytometry data within and across laboratories and facilitate the adoption of standard fluorescence units in synthetic biology and beyond. PMID:27110723

Pharmacy-enforced outpatient drug treatment protocols: a case study of Medi-Cal restrictions for cefaclor.

PubMed

McCombs, J S; Nichol, M B

1993-02-01

To evaluate whether a pharmacy-enforced treatment protocol successfully limited the use of a high-cost medication to high-risk patients. A case study cost-effectiveness analysis was conducted to evaluate a treatment protocol for cefaclor. Episodes of care were defined, healthcare expenditures for all services were aggregated, and demographic data were retrieved from a five percent random sample of California Medicaid (Medi-Cal) recipients. Data were available for episodes occurring before cefaclor was made available under Medi-Cal. Medi-Cal added cefaclor to its formulary, limiting its use to patients over 50 years of age with lower respiratory tract infections (LRTIs). The unit of analysis was an episode of outpatient antibiotic treatment. Confirmed LRTI episodes and unconfirmed LRTI cefaclor episodes were analyzed, including multiple episodes of treatment for individual patients. A total of 7855 non-cefaclor LRTI episodes and 2556 cefaclor episodes were analyzed. The primary outcome measures were healthcare expenditures three months after the initiation of antibiotic therapy, differentiated by type of service. Physicians directed cefaclor toward higher-risk patients over age 50 years, even in unconfirmed LRTI episodes. Cefaclor use was estimated to reduce posttreatment costs by $388 per patient (p < 0.001), primarily because of reduced hospital expenditures of $366 (p < 0.001). Pharmacy-enforced outpatient drug treatment protocols may be a viable alternative to restrictive formularies and prior authorization. In the case of cefaclor, the Medi-Cal treatment protocol appeared to allow high-risk patients better access to a high-cost medication while reducing total posttreatment costs.

Determination of chemical properties in 'calçot' (Allium cepa L.) by near infrared spectroscopy and multivariate calibration.

PubMed

Sans, Silvia; Ferré, Joan; Boqué, Ricard; Sabaté, José; Casals, Joan; Simó, Joan

2018-10-01

'Calçots', the immature floral stems of second-year onion resprouts, are an economically important traditional crop in Catalonia (Spain). Classical approaches to evaluating the chemical properties of 'calçots' are time consuming and expensive; near-infrared spectroscopy (NIRS) may be faster and cheaper. We used NIRS to develop partial least square (PLS) models to predict dry matter, soluble solid content, titratable acidity, and ash content in cooked 'calçots'. To guarantee the robustness of the models, calibration samples were grown and analyzed in a first season (2014-15) and validation samples in a second season (2015-16). NIRS on puree spectra estimated dry matter and soluble solid content with excellent accuracy (R 2 pred  = 0.953, 0.985 and RPD = 4.571, 8.068, respectively). However, good estimation of titratable acidity and ash content required using ground dried puree spectra (R 2 pred  = 0.852, 0.820 and RPD = 2.590, 1.987, respectively). NIRS can be a helpful tool for 'calçots' breeding and quality control. Copyright © 2018 Elsevier Ltd. All rights reserved.

Fast simulation of electromagnetic and hadronic showers in SpaCal calorimeter at the H1 experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raičević, Nataša, E-mail: raicevic@mail.desy.de; Glazov, Alexandre

2016-03-25

The fast simulation of showers induced by electrons (positrons) in the H1 lead/scintillating-fiber calorimeter, SpaCal, based on shower library technique has been presented previously. In this paper we show the results on linearity and uniformity of the reconstructed electron/positron cluster energy in electromagnetic section of Spacal for the simulations based on shower library and GFLASH shower parametrisation. The shapes of the clusters originating from photon and hadron candidates in SpaCal are analysed and experimental distributions compared with the two simulations.

Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction

PubMed Central

Lozano, María Luisa; Cook, Aaron; Bastida, José María; Paul, David S.; Iruin, Gemma; Cid, Ana Rosa; Adan-Pedroso, Rosa; Ramón González-Porras, José; Hernández-Rivas, Jesús María; Fletcher, Sarah J.; Johnson, Ben; Morgan, Neil; Ferrer-Marin, Francisca; Vicente, Vicente; Sondek, John; Watson, Steve P.; Bergmeier, Wolfgang

2016-01-01

In addition to mutations in ITG2B or ITGB3 genes that cause defective αIIbβ3 expression and/or function in Glanzmann’s thrombasthenia patients, platelet dysfunction can be a result of genetic variability in proteins that mediate inside-out activation of αIIbβ3. The RASGRP2 gene is strongly expressed in platelets and neutrophils, where its encoded protein CalDAG-GEFI facilitates the activation of Rap1 and subsequent activation of integrins. We used next-generation sequencing (NGS) and whole-exome sequencing (WES) to identify 2 novel function-disrupting mutations in RASGRP2 that account for bleeding diathesis and platelet dysfunction in 2 unrelated families. By using a panel of 71 genes, we identified a homozygous change (c.1142C>T) in exon 10 of RASGRP2 in a 9-year-old child of Chinese origin (family 1). This variant led to a p.Ser381Phe substitution in the CDC25 catalytic domain of CalDAG-GEFI. In 2 Spanish siblings from family 2, WES identified a nonsense homozygous variation (c.337C>T) (p.Arg113X) in exon 5 of RASGRP2. CalDAG-GEFI expression was markedly reduced in platelets from all patients, and by using a novel in vitro assay, we found that the nucleotide exchange activity was dramatically reduced in CalDAG-GEFI p.Ser381Phe. Platelets from homozygous patients exhibited agonist-specific defects in αIIbβ3 integrin activation and aggregation. In contrast, α- and δ-granule secretion, platelet spreading, and clot retraction were not markedly affected. Integrin activation in the patients’ neutrophils was also impaired. These patients are the first cases of a CalDAG-GEFI deficiency due to homozygous RASGRP2 mutations that are linked to defects in both leukocyte and platelet integrin activation. PMID:27235135

Cal Tech's Program in Meteorology: 1933-1948.

NASA Astrophysics Data System (ADS)

Lewis, J. M.

1994-01-01

The California Institute of Technology (Cal Tech) established a course of study in meteorology in 1933. It was intimately tied to the upsurge of activity in commercial and military aviation that occurred in the period between the world wars. The tragic crash of the airship U.S.S. Akron provided the stimulus for including meteorology as a subprogram in the aeronautics department at Cal Tech. Thoodore von K´rm´n, head of the department and director of the school's Guggenheim Aeronautics Laboratory, masterminded the design of the program and geared it toward the solution of practical problems using the principles of dynamic meteorology. One of his doctoral students, Irving Krick, was groomed to develop the program.Robert Millikan, head of the institute, fostered an approach to science that encouraged the faculty to consuit and work with industry. In this environment, Krick established links with aviation, motion picture studios, and public utilities that would set the stage for the research thrust in meteorology. The program was primarily designed for training at the master' degree level, and a significant number of the graduates became entrepreneurs in meteorology. Based on letters of reminiscence and oral histories from some of these consulting meteorologists, it has been concluded that the Millikan/von K´rm´n philosophy of science played an important part in directing the meteorologists into the private sector.Following World War II, Lee DuBridge replaced Millikan as head of the institute. DuBridge's efforts were directed toward making the small elite school scientifically competitive in the changed conditions of a postwar world. In this climate, the merging of private business with academic work fell into disfavor. Without champions such as Millikan and von K´rm´n,the meteorology program was unable to survive.

The EuroSprite2005 Observational Campaign: an example of training and outreach opportunities for CAL young scientists

NASA Astrophysics Data System (ADS)

Chanrion, O.; Crosby, N. B.; Arnone, E.; Boberg, F.; van der Velde, O.; Odzimek, A.; Mika, Á.; Enell, C.-F.; Berg, P.; Ignaccolo, M.; Steiner, R. J.; Laursen, S.; Neubert, T.

2007-07-01

The four year "Coupling of Atmospheric Layers (CAL)" EU FP5 Research Training Network project studied unanswered questions related to transient luminous events (sprites, jets and elves) in the upper atmosphere. Consisting of ten scientific work-packages CAL also included intensive training and outreach programmes for the young scientists hired. Educational activities were based on the following elements: national PhD programmes, activities at CAL and other meetings, a dedicated summer school, and two European sprite observational campaigns. The young scientists were strongly involved in the latter and, as an example, the "EuroSprite2005" observational campaign is presented in detail. Some of the young scientists participated in the instrument set-up, others in the campaign logistics, some coordinated the observations, and others gathered the results to build a catalogue. During the four-month duration of this campaign, all of them took turns in operating the system and making their own night observations. The ongoing campaign activities were constantly advertised and communicated via an Internet blog. In summary the campaign required all the CAL young scientists to embark on experimental work, to develop their organisational skills, and to enhance their ability to communicate their activities. The campaign was a unique opportunity to train and strengthen skills that will be an asset to their future careers and, overall, was most successful.

Views of STS-3 crew during departure activites at Ellington with family

NASA Technical Reports Server (NTRS)

1982-01-01

Views of STS-3 crew, Astronauts Jack R. Lousma, left, and C. Gordon Fullerton prior to their departure in T-38 aircraft from Ellington Air Force Base for the launch of STS-3 (28700); Some of the family members of astronaut crew are greeted by a crowd of spectators on hand for Lousma and Fullerton's departure. Matthew Lousma is standing at the microphone in center of the frame, flanked by Mrs. Gratia Kay Lousma (left) and Mrs. Maria Fullerton. Left to right in front are Mary Lousma, Andrew Fullerton and Molly Fullerton (28701-2); Astronaut Lousma walks away from microphone after greeting news media representatives and public prior to departure for Kennedy (28703); Astronaut Lousma talking to Fullerton, left, and Astronuat Brewster H. Shaw, center before boarding T-38's to leave for KSC (28704); Lousma, left, and Fullerton pause at Ellington prior to their departure in T-38 aircraft for KSC (28705); Lousma, right, and Fullerton greet crowd on hand at Ellington for their departure to KSC

Chemical and Physical Properties of Hi-Cal-2

NASA Technical Reports Server (NTRS)

Spakowski, A. E.; Allen, Harrison, Jr.; Caves, Robert M.

1955-01-01

As part of the Navy Project Zip to consider various boron-containing materials as possible high-energy fuels, the chemical and physical properties of Hi-Cal-2 prepared by the Callery Chemical Company were evaluated at the NACA Lewis laboratory. Elemental chemical analysis, heat of combustion, vapor pressure and decomposition, freezing point, density, self ignition temperature, flash point, and blow-out velocity were determined for the fuel. Although the precision of measurement of these properties was not equal to that obtained for hydrocarbons, this special release research memorandum was prepared to make the data available as soon as possible.

Calcium diacylglycerol guanine nucleotide exchange factor I (CalDAG-GEFI) gene mutations in a thrombopathic Simmental calf.

PubMed

Boudreaux, M K; Schmutz, S M; French, P S

2007-11-01

Simmental thrombopathia is an inherited platelet disorder that closely resembles the platelet disorders described in Basset Hounds and Eskimo Spitz dogs. Recently, two different mutations in the gene encoding calcium diacylglycerol guanine nucleotide exchange factor I (CalDAG-GEFI) were described to be associated with the Basset Hound and Spitz thrombopathia disorders, and a third distinct mutation was identified in CalDAG-GEFI in thrombopathic Landseers of European Continental Type. The gene encoding CalDAG-GEFI was sequenced using DNA obtained from normal cattle and from a thrombopathic calf studied in Canada. The affected calf was found to have a nucleotide change (c.701 T>C), which would result in the substitution of a proline for a leucine within structurally conserved region two (SCR2) of the catalytic domain of the protein. This change is likely responsible for the thrombopathic phenotype observed in Simmental cattle and underscores the critical nature of this signal transduction protein in platelets.

The TileCal Online Energy Estimation for the Next LHC Operation Period

NASA Astrophysics Data System (ADS)

Sotto-Maior Peralva, B.; ATLAS Collaboration

2015-05-01

The ATLAS Tile Calorimeter (TileCal) is the detector used in the reconstruction of hadrons, jets and missing transverse energy from the proton-proton collisions at the Large Hadron Collider (LHC). It covers the central part of the ATLAS detector (|η| < 1.6). The energy deposited by the particles is read out by approximately 5,000 cells, with double readout channels. The signal provided by the readout electronics for each channel is digitized at 40 MHz and its amplitude is estimated by an optimal filtering algorithm, which expects a single signal with a well-defined shape. However, the LHC luminosity is expected to increase leading to pile-up that deforms the signal of interest. Due to limited resources, the current hardware setup, which is based on Digital Signal Processors (DSP), does not allow the implementation of sophisticated energy estimation methods that deal with the pile-up. Therefore, the technique to be employed for online energy estimation in TileCal for next LHC operation period must be based on fast filters such as the Optimal Filter (OF) and the Matched Filter (MF). Both the OF and MF methods envisage the use of the background second order statistics in its design, more precisely the covariance matrix. However, the identity matrix has been used to describe this quantity. Although this approximation can be valid for low luminosity LHC, it leads to biased estimators under pile- up conditions. Since most of the TileCal cell present low occupancy, the pile-up, which is often modeled by a non-Gaussian distribution, can be seen as outlier events. Consequently, the classical covariance matrix estimation does not describe correctly the second order statistics of the background for the majority of the events, as this approach is very sensitive to outliers. As a result, the OF (or MF) coefficients are miscalculated leading to a larger variance and biased energy estimator. This work evaluates the usage of a robust covariance estimator, namely the Minimum

Development and evaluation of a stand-alone web-based CAL program. A case study.

PubMed

Perryer, G; Walmsley, A D; Barclay, C W; Shaw, L; Smith, A J

2000-08-01

The use of web browser technology allows the construction of computer-aided learning programs which will have a familiar interface to dentists. This paper reports on the evaluation of a web-based CAL program which covered the topic of tooth wear with an emphasis on the rôle of erosion in its aetiology. Evaluation of the software was made by 50 dentists contacted by an electronic mailing list. They completed a questionnaire which evaluated aspects of the functionality of the program educational objectives. The average age of the dentists was 39 years (range 24-70) and 82% were male. The average time of use was 1 h 10 min (range 15 min to 3 h). A significant change in their knowledge of tooth wear before and after using the program was recorded. Both the use of patient cases and leaflets scored highly with other aspects such as treatment planning and patient advice receiving high marks. All dentists commented that they had gained greater knowledge with particular reference to treatment and advice of tooth wear problems. 34 dentists (68%) found the web interface easy to use. Negative comments were mainly attributed to the quality of the pictures (4/50) which were corrected in the final release version. Respondents were asked to compare the program to other educational media on the same subject. 80% rated this CAL program as better than video, and 14% claimed it was as good as video. 84% rated it better than books, and 14% said it was as good as books. 98% preferred it to audio tapes and 86% preferred it to journals. The average amount that they would pay for a CAL package such as "tooth wear" would be 42 ECU. It is concluded that web browser software is a suitable medium for the use of a CAL program and this is reflected in its ease of use by dentists.

SiPM-based azimuthal position sensor in ANITA-IV Hi-Cal Antarctic balloon experiment

NASA Astrophysics Data System (ADS)

Novikov, A.; Besson, D.; Chernysheva, I.; Dmitrenko, V.; Grachev, V.; Petrenko, D.; Prohira, S.; Shustov, A.; Ulin, S.; Uteshev, Z.; Vlasik, K.

2017-01-01

Hi-Cal (High-Altitude Calibration) is a balloon-borne experiment that will be launched in December, 2016 in Antarctica following ANITA-IV (Antarctic Impulsive Transient Antenna) and will generate a broad-band pulse over the frequency range expected from radiation induced by a cosmic ray shower. Here, we describe a device based on an array of silicon photomultipliers (SiPMs) for determination of the azimuthal position of Hi-Cal. The angular resolution of the device is about 3 degrees. Since at the float altitude of ˜38 km the pressure will be ˜0.5 mbar and temperature ˜ - 20 °C, the equipment has been tested in a chamber over a range of corresponding pressures (0.5 ÷ 1000) mbar and temperatures (-40 ÷ +50) °C.

The Adaptation Study of the Questionnaires of the Attitude towards CALL (A-CALL), the Attitude towards CAL (A-CAL), the Attitude towards Foreign Language Learning (A-FLL) to Turkish Language

ERIC Educational Resources Information Center

Erdem, Cahit; Saykili, Abdullah; Kocyigit, Mehmet

2018-01-01

This study primarily aims to adapt the Foreign Language Learning (FLL), Computer assisted Learning (CAL) and Computer assisted Language Learning (CALL) scales developed by Vandewaetere and Desmet into Turkish context. The instrument consists of three scales which are "the attitude towards CALL questionnaire" ("A-CALL")…

A Lactose-Binding Lectin from the Marine Sponge Cinachyrella Apion (Cal) Induces Cell Death in Human Cervical Adenocarcinoma Cells

PubMed Central

Rabelo, Luciana; Monteiro, Norberto; Serquiz, Raphael; Santos, Paula; Oliveira, Ruth; Oliveira, Adeliana; Rocha, Hugo; Morais, Ana Heloneida; Uchoa, Adriana; Santos, Elizeu

2012-01-01

Cancer represents a set of more than 100 diseases, including malignant tumors from different locations. Strategies inducing differentiation have had limited success in the treatment of established cancers. Marine sponges are a biological reservoir of bioactive molecules, especially lectins. Several animal and plant lectins were purified with antitumor activity, mitogenic, anti-inflammatory and antiviral, but there are few reports in the literature describing the mechanism of action of lectins purified from marine sponges to induce apoptosis in human tumor cells. In this work, a lectin purified from the marine sponge Cinachyrella apion (CaL) was evaluated with respect to its hemolytic, cytotoxic and antiproliferative properties, besides the ability to induce cell death in tumor cells. The antiproliferative activity of CaL was tested against HeLa, PC3 and 3T3 cell lines, with highest growth inhibition for HeLa, reducing cell growth at a dose dependent manner (0.5–10 µg/mL). Hemolytic activity and toxicity against peripheral blood cells were tested using the concentration of IC50 (10 µg/mL) for both trials and twice the IC50 for analysis in flow cytometry, indicating that CaL is not toxic to these cells. To assess the mechanism of cell death caused by CaL in HeLa cells, we performed flow cytometry and western blotting. Results showed that lectin probably induces cell death by apoptosis activation by pro-apoptotic protein Bax, promoting mitochondrial membrane permeabilization, cell cycle arrest in S phase and acting as both dependent and/or independent of caspases pathway. These results indicate the potential of CaL in studies of medicine for treating cancer. PMID:22690140

Climate forcing due to the 8200 cal yr BP event observed at Early Neolithic sites in the eastern Mediterranean

NASA Astrophysics Data System (ADS)

Weninger, Bernhard; Alram-Stern, Eva; Bauer, Eva; Clare, Lee; Danzeglocke, Uwe; Jöris, Olaf; Kubatzki, Claudia; Rollefson, Gary; Todorova, Henrieta; van Andel, Tjeerd

2006-11-01

We explore the hypothesis that the abrupt drainage of Laurentide lakes and associated rapid switch of the North Atlantic thermohaline circulation 8200 yr ago had a catastrophic influence on Neolithic civilisation in large parts of southeastern Europe, Anatolia, Cyprus, and the Near East. The event at 8200 cal yr BP is observed in a large number of high-resolution climate proxies in the Northern Hemisphere, and in many cases corresponds to markedly cold and arid conditions. We identify the relevant archaeological levels of major Neolithic settlements in Central Anatolia, Cyprus, Greece and Bulgaria, and examine published stratigraphic, architectural, cultural and geoarchaeological studies for these sites. The specific archaeological events and processes we observe at a number of these sites during the study interval 8400-8000 cal yr BP lead us to refine some previously established Neolithisation models. The introduction of farming to South-East Europe occurs in all study regions (Thrace, Macedonia, Thessaly, Bulgaria) near 8200 cal yr BP. We observe major disruptions of Neolithic cultures in the Levant, North Syria, South-East Anatolia, Central Anatolia and Cyprus, at the same time. We conclude that the 8200 cal yr BP aridity event triggered the spread of early farmers, by different routes, out of West Asia and the Near East into Greece and Bulgaria.

MOCR activity during Day 6 of STS-3 mission

NASA Technical Reports Server (NTRS)

1982-01-01

Andrew A. Fullerton, the six-year-old son of STS-3 pilot C. Gordon Fullerton, watches a television monitor in the mission control center's viewing room (28802); Mrs. Marie J. Fullerton in the mission control center's viewing room. Other members of the STS-3 pilot's family are seated on each side of Mrs. Fullerton. His sister, Jeanne Dockham, is at left foreground; son Andrew A., at right foreground. Mr. and Mrs. E. G. Buettner, Mrs. Fullerton's parents, are seated at center, and beyond them is Mrs. Charles R. Fullerton, the astronaut's mother (28803); Mary Ann Austin seated at the remote manipulator sytem (RMS) console in the mission operations control room (MOCR) shares the scene with a representation of a 1/15-scale model of the Canadian-built remote manipulator system arm (28804).

CalFitter: a web server for analysis of protein thermal denaturation data.

PubMed

Mazurenko, Stanislav; Stourac, Jan; Kunka, Antonin; Nedeljkovic, Sava; Bednar, David; Prokop, Zbynek; Damborsky, Jiri

2018-05-14

Despite significant advances in the understanding of protein structure-function relationships, revealing protein folding pathways still poses a challenge due to a limited number of relevant experimental tools. Widely-used experimental techniques, such as calorimetry or spectroscopy, critically depend on a proper data analysis. Currently, there are only separate data analysis tools available for each type of experiment with a limited model selection. To address this problem, we have developed the CalFitter web server to be a unified platform for comprehensive data fitting and analysis of protein thermal denaturation data. The server allows simultaneous global data fitting using any combination of input data types and offers 12 protein unfolding pathway models for selection, including irreversible transitions often missing from other tools. The data fitting produces optimal parameter values, their confidence intervals, and statistical information to define unfolding pathways. The server provides an interactive and easy-to-use interface that allows users to directly analyse input datasets and simulate modelled output based on the model parameters. CalFitter web server is available free at https://loschmidt.chemi.muni.cz/calfitter/.

Sedimentary Evidence for a Rapid Sea Level Rise at 7,600 cal yr BP from North-Central Cuba

NASA Astrophysics Data System (ADS)

Peros, M. C.; Agosta G'meiner, A. M.; Collins, S.

2016-12-01

A lack of high-resolution relative sea level (RSL) proxy data has meant that the pattern of early Holocene RSL change in the Caribbean is poorly understood. A RSL curve published by Toscano and Macintyre (2003) using inter-tidal mangrove peats and submerged corals suggests RSL underwent a relatively fast and `smooth' curvilinear increase during the Holocene. However, others, such as Blanchon and Shaw (1995), suggest that RSL increased rapidly at around 7600 cal yr BP, in response to the final stages of the melting of the Laurentide Ice Sheet (melt water pulse 1C or catastrophic rise event 3). We investigated this question using multi-proxy data from a flooded sinkhole (Cenote Jennifer) on the north coast of central Cuba. Cenote Jennifer is located 7 m above mean sea level and 2 km from the Bahamas Channel and appears to have a high degree of connectivity with the ocean through a network of underground caverns. The water depth is 13 m and the bottommost 5 m is anoxic. A sediment core collected from Cenote Jennifer was studied using loss-on-ignition, pollen analysis, high-resolution XRF core-scanning, and grain size analysis. An age-depth model was generated for the core by AMS dating. The results show that the bottommost stratigraphic unit ( 9000 to 7600 cal yr BP) is a fine-grained carbonate-rich mud (i.e., marl). This unit abruptly transitions into finely laminated organic-rich sediment from 7600 cal yr BP to the present. The pollen analysis shows that the sinkhole supported a cattail (Typha) community until 7600 cal yr BP, indicating low water levels ( 1 m). At 7600 cal yr BP, the cattail community disappeared and the vegetation of the surrounding bedrock became dominated by a thorny coastal scrubland. In addition, a 3 cm thick fining-upward siliciclastic unit is present immediately above the marl-organic contact, suggesting: 1) a marine sediment source given the limestone-dominated nature of the region, and 2) the presence of a short-duration, high

Progress toward studies of bubble-geometry Bose-Einstein condensates in microgravity with a ground-based prototype of NASA CAL

NASA Astrophysics Data System (ADS)

Lundblad, Nathan; Jarvis, Thomas; Paseltiner, Daniel; Lannert, Courtney

2016-05-01

We have proposed using NASA's Cold Atom Laboratory (CAL, launching to the International Space Station in 2017) to generate bubble-geometry Bose-Einstein condensates through radiofrequency dressing of an atom-chip magnetic trap. This geometry has not been truly realized terrestrially due to the perturbing influence of gravity, making it an ideal candidate for microgravity investigation aboard CAL. We report progress in the construction of a functional prototype of the orbital BEC apparatus: a compact atom-chip machine loaded by a 2D+MOT source, conventional 3D MOT, quadrupole trap, and transfer coil. We also present preliminary modeling of the dressed trap uniformity, which will crucially inform the geometric closure of the BEC shell surface as atom number, bubble radius, and bubble aspect ratio are varied. Finally, we discuss plans for experimental sequences to be run aboard CAL guided by intuition from ground-based prototype operation. JPL 1502172.

Funnel Beaker weather (6200-4900 cal BP) - reconstructed from the palaeolimnological record of synchronously deposited varves in northern Germany

NASA Astrophysics Data System (ADS)

Dreibrodt, Stefan; Zahrer, Jürgen; Brauer, Achim

2013-04-01

Depositional patterns of synchronously deposited varves of Lake Belauer See and Lake Poggensee (northern Germany) were studied on thin sections under the microscope comparatively. Events and trends that occurred synchronously in the lake systems were detected and interpret as limnologic responses to supra-regional extrinsic (climate) drivers. The different thresholds of the compared lake systems implied by different lake size were utilized to infer about weather conditions. For Lake Belauer See microfacies types of sub-recent varves were proved to reflect responses of certain meteorological conditions (e.g. severity of winters). A short weather anomaly at around 5950 cal BP was detected. Cold summers of about 40 successive years (probably with sudden frost events) lead to breaks of the thermal summer stratification and the associated carbonate precipitation. Instead renewed blooms of planctic diatoms occurred. The subsequent interval of the Funnel Beaker Culture seems to have experienced a period with favorable wea¬ther conditions, with warm summers and not extra-ordinary severe winters. Between ca. 5400 and 5340 cal BP an interval with pronounced warm winters is indicated. The favorable weather conditions termina¬ted abruptly at around 5275 cal BP when the weather (in particular summers) became colder. The comparison of the sediment sequences also provides evidence for the asynchronic onset of anthropogenic activity in the catchment areas of the lakes. A significant increase of minerogenic matter (quartz grains) indication soil erosion in the lake catchment started at ca. 3850 cal BC in Lake Poggensee, and at ca. 3500 cal BC in Lake Belau. Cycles of minerogenic input have been detected with duration of 20-25 years. Whether these cycles could represent slash and burn cycles has to be studied further.

Organic Aerosol Composition and Sources in Pasadena, California during the 2010 CalNex Campaign

EPA Science Inventory

Organic aerosols (OA) in Pasadena are characterized using multiple measurements from the California Research at the Nexus of Air Quality and Climate Change (CalNex) campaign. Five OA components are identified using positive matrix factorization including hydrocarbon-like OA (HOA) ...

Caloric Value of Some Forest Fuels of the Southern United States

Treesearch

Walter A. Hough

1969-01-01

The caloric value of a variety of southern forest fuels was determined in an oxygen bomb calorimeter. High heat values ranged between about 3,600 and 5,200 cal./g. for fuels as sampled and between 4,500 and 5,600 cal./g. for fuels on an ash-free basis. Additional tests of forest fuels from the Southern, Eastern, and North Central United States showed a...

RUGs and "Medi-Cal" systems for classifying nursing home patients.

PubMed

Grimaldi, P L

1985-12-01

Medicare and most state Medicaid programs currently use indirect case-mix measures to determine reimbursement for nursing home care. In the future, however, they probably will incorporate more direct case-mix measures into their payment systems. Care must be exercised in designing a case-based prospective payment system to ensure that its financial incentives motivate providers to expedite recovery, prevent deterioration, and admit heavy-care patients. For example, although use of a services-rendered approach helps guarantee that care will be provided when needed, it also offers providers an incentive to furnish a service regardless of whether it is in the patient's best interest. Consideration must be given to the frequency with which patients are reassessed. The implications of the timing of reassessments for quality of care also must be studied. Ideally, quality would be measured on an outcome basis--that is, payment would depend on whether targeted goals for individual patients are reached--rather than on structural or process measures alone. Two recent classification systems--Resource Utilization Groups and Medi-Cal groups--may serve as models for case-based prospective payment systems. Each method classifies patients into distinct, meaningful categories based on activities of daily living and services received.

Influence of Monsoon variations on ecosystem changes on the Central Tibetan Plateau during the last 24 ka cal BP (Invited)

NASA Astrophysics Data System (ADS)

Kasper, T.; Haberzettl, T.; Zhu, L.; Maeusbacher, R.

2013-12-01

Lakes as archives of climate and environmental change are well known and well investigated all over the world, also in high mountain areas such as the Tibetan Plateau (TP) which is one of the most important key players in global climate circulation. Lake sediment records in this area, which were subject to lots of paleoenvironmental investigations, are mostly focused on the Holocene, often showing discontinuities due to desiccation or are located at the margin of the TP, such as Lake Qinghai. Here we present the first continuous lake sediment record from the southern central TP from Lake Nam Co, comprising ~24 ka cal BP, i.e., the LGM, the post-Glacial and the entire Holocene. The record reveals environmental changes with varying intensities. Extraordinary high sediment accumulation rates (SAR = 1.3 mm a-1) and quite large quantities of minerogenic input associated with the absence of ostracods during the LGM point to a small lake within a cold and dry environment. Around 19 ka cal BP reduced SAR (~0.3 mm a-1) and the occurrence of ostracods refer to a rising lake level in a moister environment. During the post-Glacial (~16 ka cal BP) changes in the geochemical composition of the sediments and a shift in the pollen composition suggests a change in summer precipitation and wind direction associated with a stronger Indian Ocean Summer Monsoon (IOSM). Major variations in the geochemical parameters between ~12.6 and ~11.6 ka cal BP may reflect the Younger Dryas climate oscillation of the Northern Hemisphere with cool and arid environmental conditions. The most striking hydrological variation within this record occurs at ~9.5 ka cal BP in the early Holocene. A rise in TOC points to enhanced bio-productivity within the lake and the catchment as well as to hampered decomposition of organic matter at the lake floor. Pollen composition refers to alpine meadow vegetation assemblages during this time. This may reflect moist and warm conditions probably associated with a

Scaffolding and Integrated Assessment in Computer Assisted Learning (CAL) for Children with Learning Disabilities

ERIC Educational Resources Information Center

Beale, Ivan L.

2005-01-01

Computer assisted learning (CAL) can involve a computerised intelligent learning environment, defined as an environment capable of automatically, dynamically and continuously adapting to the learning context. One aspect of this adaptive capability involves automatic adjustment of instructional procedures in response to each learner's performance,…

User-Friendly Interface Developed for a Web-Based Service for SpaceCAL Emulations

NASA Technical Reports Server (NTRS)

Liszka, Kathy J.; Holtz, Allen P.

2004-01-01

A team at the NASA Glenn Research Center is developing a Space Communications Architecture Laboratory (SpaceCAL) for protocol development activities for coordinated satellite missions. SpaceCAL will provide a multiuser, distributed system to emulate space-based Internet architectures, backbone networks, formation clusters, and constellations. As part of a new effort in 2003, building blocks are being defined for an open distributed system to make the satellite emulation test bed accessible through an Internet connection. The first step in creating a Web-based service to control the emulation remotely is providing a user-friendly interface for encoding the data into a well-formed and complete Extensible Markup Language (XML) document. XML provides coding that allows data to be transferred between dissimilar systems. Scenario specifications include control parameters, network routes, interface bandwidths, delay, and bit error rate. Specifications for all satellite, instruments, and ground stations in a given scenario are also included in the XML document. For the SpaceCAL emulation, the XML document can be created using XForms, a Webbased forms language for data collection. Contrary to older forms technology, the interactive user interface makes the science prevalent, not the data representation. Required versus optional input fields, default values, automatic calculations, data validation, and reuse will help researchers quickly and accurately define missions. XForms can apply any XML schema defined for the test mission to validate data before forwarding it to the emulation facility. New instrument definitions, facilities, and mission types can be added to the existing schema. The first prototype user interface incorporates components for interactive input and form processing. Internet address, data rate, and the location of the facility are implemented with basic form controls with default values provided for convenience and efficiency using basic XForms operations

A modern documented Italian identified skeletal collection of 2127 skeletons: the CAL Milano Cemetery Skeletal Collection.

PubMed

Cattaneo, Cristina; Mazzarelli, Debora; Cappella, Annalisa; Castoldi, Elisa; Mattia, Mirko; Poppa, Pasquale; De Angelis, Danilo; Vitello, Antonio; Biehler-Gomez, Lucie

2018-06-01

The CAL Milano Cemetery Skeletal Collection is a modern and continuously growing identified osteological collection of 2127 skeletons under study in the Laboratorio di Antropologia e Odontologia Forense (LABANOF) in the Department of Biomedical Sciences for Health of the University of Milan (Italy), and part of the Collezione Antropologica LABANOF (CAL). The collection presents individuals of both sexes and of all age groups with a high representation of the elderly and an interesting sample of infants. Each individual is associated with a documentation that includes sex, age-at-death, dates of birth and death, and a death certificate that specifies the exact cause of death and the chain of events that led to it (related pathological conditions or traumatic events). It was also possible to recover for several individuals the autopsy reports and antemortem photographs. This documented osteological collection is of crucial interest in physical and forensic anthropology: it provides unique teaching opportunities and more importantly considerable research possibilities to test and develop sex and age estimation methods, investigate key subjects of forensic relevance and discuss pathological markers, among others. The aim of this paper is to introduce the CAL Milano Cemetery Skeletal Collection as a new identified skeletal collection and present its research and teaching potential. Copyright © 2018 Elsevier B.V. All rights reserved.

Assessing change in diet and biological affinity between the 4th and 3rd millennia cal BCE in the Portuguese Estremadura: a preliminary dental comparison of Feteira II and Bolores.

PubMed

Horwath, B C; Waterman, A J; Lillios, K T; Irish, J D

2014-04-01

Although the social and political changes accompanying the transition from the Neolithic through Copper Age, between the 4th and 3rd millennia cal BCE, in southwestern Iberia are reasonably well understood, much less is known about whether population movements and dietary changes accompanied these transformations. To address this question, human dental remains from the Middle through Late Neolithic site of Feteira II (3600-2900 cal BCE) and the Late Neolithic site of Bolores (2800-2600 cal BCE) in the Portuguese Estremadura were used to examine diet (microwear) and affinity (dental non-metrics). Microwear features were not found to be significantly different between Feteira II and Bolores, suggesting that the emergence of social complexity during this period did not result in large-scale changes in subsistence practices during the period of use at these sites. Using the Arizona State University Dental Anthropology System and supporting statistics, no significant difference between the samples from Feteira II and Bolores was observed, suggesting that no population replacement occurred between the Middle Neolithic and Late Neolithic/Copper Age. However, at Bolores there is some indication that there may have been demographic exchanges between southern Iberian and North African populations during the Late Neolithic/Copper Age. Copyright © 2013 Elsevier GmbH. All rights reserved.

Cal MediConnect Enrollment: Why Are Dual-Eligible Consumers in Los Angeles County Opting Out?

PubMed

McBride, Kate; Reynoso, Ana; Alunan, Tiffany; Gutierrez, Brenda; Bacong, Adrien; Moon, Marge; Bacigalupo, Anastasia; Benjamin, A E; Wallace, Steven P.; Kietzman, Kathryn G

2017-09-01

Los Angeles County has the state’s lowest rate of consumer enrollment in Cal MediConnect, a program that is responsible for the delivery and coordination of medical, behavioral health, and long-term services and support benefits for individuals who are dually eligible for Medicare and Medi-Cal. This policy brief examines the factors that influence consumer decisions and may contribute to low enrollment rates. Influential factors include consumer knowledge of health care options, perception of choice, and disruption of existing care. Differences in decision making by age, complexity of health care needs, race/ethnicity, immigration status, and primary language are also noted. Policy recommendations include engaging consumers in the planning and dissemination of information about their health care options, optimizing consumer choice and implementing the least disruptive pathway to enrollment, and recognizing and responding to the great diversity of dual-eligible consumers in Los Angeles County.

Wave Energy Prize - 1/20th Testing - CalWave Power Technologies

DOE Data Explorer

Scharmen, Wesley

2016-09-09

Data from the 1/20th scale testing data completed on the Wave Energy Prize for the CalWave Power Technologies team, including the 1/20th scale test plan, raw test data, video, photos, and data analysis results. The top level objective of the 1/20th scale device testing is to obtain the necessary measurements required for determining Average Climate Capture Width per Characteristic Capital Expenditure (ACE) and the Hydrodynamic Performance Quality (HPQ), key metrics for determining the Wave Energy Prize (WEP) winners.

Can TAD and CalTAD predict cut-out after extra-medullary fixation with new generation devices of proximal femoral fractures? A retrospective study.

PubMed

Caruso, Gaetano; Andreotti, Mattia; Pari, Carlotta; Soldati, Francesco; Gildone, Alessandro; Lorusso, Vincenzo; Massari, Leo

2017-01-01

Intramedullary and extramedullary strategies of pertrochanteric fracture fixation are still controversial, but new percutaneous devices may give advantages regarding operative time, blood loss and rate of cardiovascular complications. We retrospectively analyze our cases regarding Anteversa ® plate (Intrauma, Turin, Italy) fixation of pertrochanteric femoral fractures, focusing on the correlation between two radiographical parameters (tip-apex distance "TAD" and calcar referenced tip-apex distance "CalTAD") and the occurrence of cut-out. The purpose of this study was to determine if these predicting factors of cut-out are reliable in the treatment of proximal femoral fractures with the Anteversa plate. A series of 77 patients with 53 31-A1 fracture types and 24-A2 fractures completed a 12-month-follow-up. Clinical outcomes were evaluated according to Parker-Palmer Mobility Score at the final follow-up. TAD and CalTAD were considered to determine their correlation with cut-out events. The mean Parker-Palmer Score was 6.94 in A1 group and 7.41 in A2 group ( p  = 0.47). Mean value of TAD index was 29.58, 29.81 in the A1 group and 29.08 in the A2 group, and mean value of CalTAD index was 30.87, 31.03 in the A1 group and 30.50 in the A2 group. We observed 3 cases of implant cut-out. We shared our sample in two groups, one group with TAD and CalTAD indices lower than 25 mm and another group higher than 25 mm to evaluate how the Palmer Parker score changed and no statistical differences were found between the two groups. Taking into consideration that good clinical results were obtained for TAD and CalTAD values superior to 25 mm, the prognostic value of 25 mm of TAD and CalTAD indices might not be appropriate to this new percutaneous plate.

NO2 fluxes from Tijuana using a mobile mini-DOAS during Cal-Mex 2010

NASA Astrophysics Data System (ADS)

Rivera, Claudia; Barrera, Hugo; Grutter, Michel; Zavala, Miguel; Galle, Bo; Bei, Naifang; Li, Guohui; Molina, Luisa T.

2013-05-01

NO2 fluxes were measured using a mobile mini-DOAS during Cal-Mex 2010 field study, between May 15 and June 30, 2010, from the urban area of Tijuana, Baja California as well as the Rosarito power plant. The average calculated NO2 fluxes were 328 ± 184 (269 ± 201) g s-1, and 23.4 ± 4.9 (12.9 ± 11.9) g s-1 for Tijuana urban area and Rosarito power plant, respectively, using model based wind fields and onsite measurements (in parenthesis). Wind speed and wind direction data needed to estimate the fluxes were both modeled and obtained from radiosondes launched regularly during the field campaign, whereas the mixing layer height throughout the entire field campaign was measured using a ceilometer. Large variations in the NO2 fluxes from both the Tijuana urban area and Rosarito power plant were observed during Cal-Mex 2010; however, the variability was less when model based wind fields were used. Qualitative comparisons of modeled and measured plumes from the Tijuana urban area and Rosarito power plant showed good agreement.

A Discussion on Personnel Exposure to Posttest Byproducts from a 50-cal. Light Gas Gun

NASA Technical Reports Server (NTRS)

Henderson, Don; Rodriquez, Karen

2007-01-01

In January of 2002, employees working in the Hypervelocity Test Facility (HTF) at White Sands Test Facility (WSTF) began to notice common physical complaints. These included loss of smell, loss of taste, skin irritation, a burning sensation of the mucus membranes, and redness and chapping of the lips. These conditions extended to home during the weekends and throughout holiday breaks as well. Concerns about air contaminants were raised with regard to the operation of the .50-cal. two-stage light gas gun (2SLGG). Employees suspected that these conditions might be caused by air contaminants from small leaks at the gun pump tube joint at the breech, and exhaust gas entrainment into the WAC systems. The WSTF Industrial Hygienist (IH) was notified and samples were collected using the MIRAN infrared spectrometer (real time) air sampler on 08 January 2002 at the SO-cal. gun. The results from this screening test suggested the need for more detailed investigations with analytical sampling and analysis.

Anthocyanins from black rice (Oryza sativa L.) demonstrate antimetastatic properties by reducing MMPs and NF-κB expressions in human oral cancer CAL 27 cells.

PubMed

Fan, Ming-Jen; Wang, I-Chen; Hsiao, Yung-Ting; Lin, Hui-Yi; Tang, Nou-Ying; Hung, Tzu-Chieh; Quan, Christine; Lien, Jin-Cherng; Chung, Jing-Gung

2015-01-01

Aside from the commonly known white rice lines, colored varieties also exist. These varieties have historically been used in Chinese medicine. Anthocyanins, a large group of natural polyphenols existing in a variety of daily fruits and vegetables, have been widely recognized as cancer chemopreventive agents. The primary objective of cancer treatment strategies has traditionally focused on preventing the occurrence of metastasis. In this research the antimetastatic mechanism of anthocyanins on the invasion/migration of human oral CAL 27 cells was performed using a transwell to quantify the migratory potential of CAL 27 cells and the results show that anthocyanins can inhibit the in vitro migration and invasion of CAL 27 cancer cells. In addition, the gelatin zymography assay indicated that anthocyanins inhibited the activity of matrix metalloproteinases-2 (MMP-2). Western blotting assay also demonstrated that anthocyanins inhibited the associated protein expression of migration/invasion of CAL 27 cell. Immunofluorescence staining proved that anthocyanins inhibited nuclear factor kappa B p65 (NF-κB p65) expressions. These results demonstrated that anthocyanins from a species of black rice (selected purple glutinous indica rice cultivated at Asia University) could suppress CAL 27 cell metastasis by reduction of MMP-2, MMP-9, and NF-κB p65 expression through the suppression of PI3K/Akt pathway and inhibition of NF-κB levels.

CalPro: a spreadsheet program for the management of California mixed-conifer stands.

Treesearch

Jingjing Liang; Joseph Buongiorno; Robert A. Monserud

2004-01-01

CalPro is an add-in program developed to work with Microsoft Excel to simulate the growth and management of uneven-aged mixed-conifer stands in California. Its built-in growth model was calibrated from 177 uneven-aged plots on industry and other private lands. Stands are described by the number of trees per acre in each of nineteen 2-inch diameter classes in...

Dietary shift after 3600 cal yr BP and its influencing factors in northwestern China: Evidence from stable isotopes

NASA Astrophysics Data System (ADS)

Ma, Minmin; Dong, Guanghui; Jia, Xin; Wang, Hui; Cui, Yifu; Chen, Fahu

2016-08-01

Human diets rely on natural resource availability and can reflect social and cultural values. When environments, societies, and cultures change, diets may also shift. This study traced the extent of dietary change and the factors influencing such change. Through stable carbon and nitrogen isotopic analysis of late Neolithic and early Bronze Age human and animal bone collagen, we found that significant shifts in human diets were closely associated with intercontinental cultural exchanges in Eurasia and climate change in northwestern China. The isotopic evidence indicated that human diets mainly consisted of C4 foodstuffs (presumably millet and/or animals fed with C4 foods) around 4000 calibrated years before the present (cal yr BP), corresponding to the flourishing of millet agriculture in the context of the optimal climate conditions of the mid-Holocene. Subsequently, more C3 foods (probably wheat, barley, and animals fed with C3 foods) were added to human diets post-3600 cal yr BP when the climate became cooler and drier. Such dietary variation is also consistent with the increasing intensity of long-distance exchange after 4000 cal yr BP. While many factors can lead to human dietary shifts (e.g. climate change, population growth, cultural factors, and human migration), climate may have been a key factor in Gansu and Qinghai.

Dietary shift after 3600 cal yr BP and its influencing factors in northwestern China: Evidence from stable isotopes

NASA Astrophysics Data System (ADS)

Ma, Minmin; Dong, Guanghui; Jia, Xin; Wang, Hui; Cui, Yifu; Chen, Fahu

2017-04-01

:Human diets rely on natural resource availability and can reflect social and cultural values. When environments, societies, and cultures change, diets may also shift. This study traced the extent of dietary change and the factors influencing such change. Through stable carbon and nitrogen isotopic analysis of late Neolithic and early Bronze Age human and animal bone collagen, we found that significant shifts in human diets were closely associated with intercontinental cultural exchanges in Eurasia and climate change in northwestern China. The isotopic evidence indicated that human diets mainly consisted of C4 foodstuffs (presumably millet and/or animals fed with C4 foods) around 4000 calibrated years before the present (cal yr BP), corresponding to the flourishing of millet agriculture in the context of the optimal climate conditions of the mid-Holocene. Subsequently, more C3 foods (probably wheat, barley, and animals fed with C3 foods) were added to human diets post-3600 cal yr BP when the climate became cooler and drier. Such dietary variation is also consistent with the increasing intensity of long-distance exchange after 4000 cal yr BP. While many factors can lead to human dietary shifts (e.g. climate change, population growth, cultural factors, and human migration), climate may have been a key factor in Gansu and Qinghai.

Radiometric Calibration of Earth Science Imagers Using HyCalCam on the Deep Space Gateway Platform

NASA Astrophysics Data System (ADS)

Butler, J. J.; Thome, K. J.

2018-02-01

HyCalCam, an SI-traceable imaging spectrometer on the Deep Space Gateway, acquires images of the Moon and Earth to characterize the lunar surface and terrestrial scenes for use as absolute calibration targets for on-orbit LEO and GEO sensors.

Aerodynamic design of the Cal Poly Da Vinci Human-Powered Helicopter

NASA Technical Reports Server (NTRS)

Larwood, Scott; Saiki, Neal

1990-01-01

This paper will discuss the methodology used in designing the rotor and drive propellers for the third generation Cal Poly Da Vinci Human-Powered Helicopter. The rotor was designed using a lifting surface, uniform inflow hover analysis code and the propeller was designed using a minimum induced-loss method. Construction, geometry, and operating considerations are discussed as they impact the designs. Optimization of the design performance is also explained. The propellers were tested in a wind tunnel and results are compared with theoretical data. Successful flight tests of the Da Vinci III are discussed.

A modern documented Italian identified skeletal collection of 2127 skeletons: The CAL Milano Cemetery Skeletal Collection.

PubMed

Cattaneo, Cristina; Mazzarelli, Debora; Cappella, Annalisa; Castoldi, Elisa; Mattia, Mirko; Poppa, Pasquale; De Angelis, Danilo; Vitello, Antonio; Biehler-Gomez, Lucie

2018-04-24

The CAL Milano Cemetery Skeletal Collection is a modern and continuously growing identified osteological collection of 2127 skeletons under study in the Laboratorio di Antropologia e Odontologia Forense (LABANOF) in the Department of Biomedical Sciences for Health of the University of Milan (Italy), and part of the Collezione Antropologica LABANOF (CAL). The collection presents individuals of both sexes and of all age groups with a high representation of elderly and an interesting sample of infants. Each individual is associated with a documentation that includes sex, age-at-death, dates of birth and death, and a death certificate that specifies the exact cause of death and the chain of events that led to it (related pathological conditions or traumatic events). It was also possible to recover for several individuals the autopsy reports and antemortem photographs. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

State Fiscal Year 1997-2000 State Transportation Improvement Program (STIP) Cleveland/Akron/Lorain Moderate Ozone Nonattainment Area Air Quality Conformity Documentation

DOT National Transportation Integrated Search

1996-06-01

This document, which is a portion of the Ohio 1997-2000 State Transportation Improvement Program (STIP), describes the conformity determination for the former eight county Cleveland/Akron/Lorain (CAL) Moderate Ozone Nonattainment Area, which includes...

The late Holocene dry period: multiproxy evidence for an extended drought between 2800 and 1850 cal yr BP across the central Great Basin, USA

USGS Publications Warehouse

Mensing, Scott A.; Sharpe, Saxon E.; Tunno, Irene; Sada, Don W.; Thomas, Jim M.; Starratt, Scott W.; Smith, Jeremy

2013-01-01

Evidence of a multi-centennial scale dry period between ∼2800 and 1850 cal yr BP is documented by pollen, mollusks, diatoms, and sediment in spring sediments from Stonehouse Meadow in Spring Valley, eastern central Nevada, U.S. We refer to this period as the Late Holocene Dry Period. Based on sediment recovered, Stonehouse Meadow was either absent or severely restricted in size at ∼8000 cal yr BP. Beginning ∼7500 cal yr BP, the meadow became established and persisted to ∼3000 cal yr BP when it began to dry. Comparison of the timing of this late Holocene drought record to multiple records extending from the eastern Sierra Nevada across the central Great Basin to the Great Salt Lake support the interpretation that this dry period was regional. The beginning and ending dates vary among sites, but all sites record multiple centuries of dry climate between 2500 and 1900 cal yr BP. This duration makes it the longest persistent dry period within the late Holocene. In contrast, sites in the northern Great Basin record either no clear evidence of drought, or have wetter than average climate during this period, suggesting that the northern boundary between wet and dry climates may have been between about 40° and 42° N latitude. This dry in the southwest and wet in the northwest precipitation pattern across the Great Basin is supported by large-scale spatial climate pattern hypotheses involving ENSO, PDO, AMO, and the position of the Aleutian Low and North Pacific High, particularly during winter.

Followup Study of Transfer Students from C.O.S. to California State University, Fresno, & California Poly-Technic State University, San Luis Obispo, Fall 1984.

ERIC Educational Resources Information Center

Webb, Elaine

A study was conducted at College of the Sequoias (COS) to assess the academic success of students transferring to California State University, Fresno (Fresno State), and California Poly-Technic State University, San Luis Obispo (Cal-Poly). The study focused on the number of units completed at COS, grade point average (GPA) at COS, COS units…

Comparison of the Fullerton Advanced Balance Scale, Mini-BESTest, and Berg Balance Scale to Predict Falls in Parkinson Disease.

PubMed

Schlenstedt, Christian; Brombacher, Stephanie; Hartwigsen, Gesa; Weisser, Burkhard; Möller, Bettina; Deuschl, Günther

2016-04-01

The correct identification of patients with Parkinson disease (PD) at risk for falling is important to initiate appropriate treatment early. This study compared the Fullerton Advanced Balance (FAB) scale with the Mini-Balance Evaluation Systems Test (Mini-BESTest) and Berg Balance Scale (BBS) to identify individuals with PD at risk for falls and to analyze which of the items of the scales best predict future falls. This was a prospective study to assess predictive criterion-related validity. The study was conducted at a university hospital in an urban community. Eighty-five patients with idiopathic PD (Hoehn and Yahr stages: 1-4) participated in the study. Measures were number of falls (assessed prospectively over 6 months), FAB scale, Mini-BESTest, BBS, and Unified Parkinson's Disease Rating Scale. The FAB scale, Mini-BESTest, and BBS showed similar accuracy to predict future falls, with values for area under the curve (AUC) of the receiver operating characteristic (ROC) curve of 0.68, 0.65, and 0.69, respectively. A model combining the items "tandem stance," "rise to toes," "one-leg stance," "compensatory stepping backward," "turning," and "placing alternate foot on stool" had an AUC of 0.84 of the ROC curve. There was a dropout rate of 19/85 participants. The FAB scale, Mini-BESTest, and BBS provide moderate capacity to predict "fallers" (people with one or more falls) from "nonfallers." Only some items of the 3 scales contribute to the detection of future falls. Clinicians should particularly focus on the item "tandem stance" along with the items "one-leg stance," "rise to toes," "compensatory stepping backward," "turning 360°," and "placing foot on stool" when analyzing postural control deficits related to fall risk. Future research should analyze whether balance training including the aforementioned items is effective in reducing fall risk. © 2016 American Physical Therapy Association.

The immunomodulatory activities of pullulan and its derivatives in human pDC-like CAL-1 cell line.

PubMed

Wang, Fang; Qiao, Linan; Chen, Liwei; Zhang, Cong; Wang, Yan; Wang, Yinsong; Liu, Yuanyuan; Zhang, Ning

2016-05-01

In this study, acidic and alkaline pullulan derivates were synthesized and their immunomodulatory activities compared to pullulan were investigated in human pDC-like CAL-1 cell line. Pullulan was reacted respectively with succinic anhydride and N-(-2-aminoethyl)-1,3-propanediamine/N,N-carbonyl diimidazole to form acidic pullulan monosuccinate (SUPL) and alkaline pullulan-g-N-(-2-aminoethyl)-1,3-propanediamine (AMPL). In CAL-1 cells, pullulan, SUPL and AMPL up-regulated the mRNA expressions of type I interferons (IFN), including IFN-α and IFN-β1, and some other proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-23 (IL-23), and also significantly enhanced the protein expressions of IFN-α and TNF-α. The activation of nuclear factor kappa B (NF-κB) and the nuclear translocations of interferon regulation factors (IRFs), including IRF-3 and IRF-5, exhibited pivotal roles in the immune responses induced by pullulan, SUPL and AMPL. By comparison, pullulan and SUPL displayed weak effects on the activation of CAL-1 cells, but AMPL showed remarkably enhanced immunomodulatory activities, which were comparable to that induced by R848, an agonist for Toll-like receptor (TLR) 7/8. Our results suggested that AMPL, as an alkaline pullulan derivative, could be used as a potent immunomodulatory agent in the food and pharmacological fields. Copyright © 2016 Elsevier B.V. All rights reserved.

Information Technology and Disabilities, 1996.

ERIC Educational Resources Information Center

McNulty, Tom, Ed.

1996-01-01

This document consists of all issues/pages of the electronic journal "Information Technology and Disabilities" published during 1996, i.e., a total of 13 ITD articles: (1) "New CSUF (California State University at Fullerton) Braille Transcription Center Promotes Access to Postsecondary Instructional Materials for the California State University…

In Vitro Effect of the Synthetic cal14.1a Conotoxin, Derived from Conus californicus, on the Human Parasite Toxoplasma gondii

PubMed Central

De León-Nava, Marco A.; Romero-Núñez, Eunice; Luna-Nophal, Angélica; Bernáldez-Sarabia, Johanna; Sánchez-Campos, Liliana N.; Licea-Navarro, Alexei F.; Morales-Montor, Jorge; Muñiz-Hernández, Saé

2016-01-01

Toxins that are secreted by cone snails are small peptides that are used to treat several diseases. However, their effects on parasites with human and veterinary significance are unknown. Toxoplasma gondii is an opportunistic parasite that affects approximately 30% of the world’s population and can be lethal in immunologically compromised individuals. The conventional treatment for this parasitic infection has remained the same since the 1950s, and its efficacy is limited to the acute phase of infection. These findings have necessitated the search for new drugs that specifically target T. gondii. We examined the effects of the synthetic toxin cal14.1a (s-cal14.1a) from C. californicus on the tachyzoite form of T. gondii. Our results indicate that, at micromolar concentrations, s-cal14.1a lowers viability and inhibits host cell invasion (by 50% and 61%, respectively) on exposure to extracellular parasites. Further, intracellular replication decreased significantly while viability of the host cell was unaffected. Our study is the first report on the antiparasitic activity of a synthetic toxin of C. californicus. PMID:27070627

In Vitro Effect of the Synthetic cal14.1a Conotoxin, Derived from Conus californicus, on the Human Parasite Toxoplasma gondii.

PubMed

De León-Nava, Marco A; Romero-Núñez, Eunice; Luna-Nophal, Angélica; Bernáldez-Sarabia, Johanna; Sánchez-Campos, Liliana N; Licea-Navarro, Alexei F; Morales-Montor, Jorge; Muñiz-Hernández, Saé

2016-04-08

Toxins that are secreted by cone snails are small peptides that are used to treat several diseases. However, their effects on parasites with human and veterinary significance are unknown. Toxoplasma gondii is an opportunistic parasite that affects approximately 30% of the world's population and can be lethal in immunologically compromised individuals. The conventional treatment for this parasitic infection has remained the same since the 1950s, and its efficacy is limited to the acute phase of infection. These findings have necessitated the search for new drugs that specifically target T. gondii. We examined the effects of the synthetic toxin cal14.1a (s-cal14.1a) from C. californicus on the tachyzoite form of T. gondii. Our results indicate that, at micromolar concentrations, s-cal14.1a lowers viability and inhibits host cell invasion (by 50% and 61%, respectively) on exposure to extracellular parasites. Further, intracellular replication decreased significantly while viability of the host cell was unaffected. Our study is the first report on the antiparasitic activity of a synthetic toxin of C. californicus.

Modeling of Trans-boundary Transport of Air Pollutants in the California-Mexico Border Region during Cal-Mex 2010

NASA Astrophysics Data System (ADS)

Bei, N.; Zavala, M. A.; Lei, W.; Li, G.; Molina, L. T.

2010-12-01

The US and Mexico share a common air basin along the ~200 km border between California and Baja California. The economical activities in this region are heavily influenced by the international trade and commerce between Mexico and the US that mainly occurs through the borders of the sister cities of San Diego-Tijuana and Calexico-Mexicali. The diversity and differences in the characteristics of emissions sources of air pollutants in the California-Mexico border region make this an important area for the study of the chemistry and trans-boundary transport of air pollutants. During May-June of 2010, the Cal-Mex 2010 field campaign included a series of measurements aimed at characterizing the emissions from major sources in the California-Mexico border region and assessing the possible impacts of these emissions on local and regional air quality. In this work we will present the results of the use of the Comprehensive Air quality model with extensions (CAMx) in a modeling domain that includes the sister cities of San Diego-Tijuana and Calexico-Mexicali for studying events of trans-boundary transport of air pollutants during Cal-Mex 2010. The measurements obtained during the Cal-Mex 2010 field campaign are used in the evaluation of the model performance and in the design of air quality improvement policies in the California-Mexico border region.

Meteorological overview and plume transport patterns during Cal-Mex 2010

NASA Astrophysics Data System (ADS)

Bei, Naifang; Li, Guohui; Zavala, Miguel; Barrera, Hugo; Torres, Ricardo; Grutter, Michel; Gutiérrez, Wilfredo; García, Manuel; Ruiz-Suarez, Luis Gerardo; Ortinez, Abraham; Guitierrez, Yaneth; Alvarado, Carlos; Flores, Israel; Molina, Luisa T.

2013-05-01

Cal-Mex 2010 Field Study is a US-Mexico collaborative project to investigate cross-border transport of emissions in the California-Mexico border region, which took place from May 15 to June 30, 2010. The current study presents an overview of the meteorological conditions and plume transport patterns during Cal-Mex 2010 based on the analysis of surface and vertical measurements (radiosonde, ceilometers and tethered balloon) conducted in Tijuana, Mexico and the modeling output using a trajectory model (FLEXPRT-WRF) and a regional model (WRF). The WRF model has been applied for providing the meteorological daily forecasts that are verified using the available observations. Both synoptic-scale and urban-scale forecasts (including wind, temperature, and humidity) agree reasonably well with the NCEP-FNL reanalysis data and the measurements; however, the WRF model frequently underestimates surface temperature and planetary boundary layer (PBL) height during nighttime compared to measurements. Based on the WRF-FLEXPART simulations with particles released in Tijuana in the morning, four representative plume transport patterns are identified as “plume-southeast”, “plume-southwest”, “plume-east” and “plume-north”, indicating the downwind direction of the plume; this will be useful for linking meteorological conditions with observed changes in trace gases and particular matter (PM). Most of the days during May and June are classified as plume-east and plume-southeast days, showing that the plumes in Tijuana are mostly carried to the southeast and east of Tijuana within the boundary layer during daytime. The plume transport directions are generally consistent with the prevailing wind directions on 850 hPa. The low level (below 800 m) wind, temperature, and moisture characteristics are different for each plume transport category according to the measurements from the tethered balloon. Future studies (such as using data assimilation and ensemble forecasts) will be

Rapid settlement of Majuro Atoll, central Pacific, following its emergence at 2000 years CalBP

NASA Astrophysics Data System (ADS)

Kayanne, Hajime; Yasukochi, Toru; Yamaguchi, Toru; Yamano, Hiroya; Yoneda, Minoru

2011-10-01

Atoll islands are areas of low, flat land, and the sustainability of habitable land in such environments is sensitive to even slight changes in sea level. The projected rise in sea level during this century may lead to the submergence of atoll islands and the widespread loss of habitable land. However, the actual time sequence of past sea level change, island emergence events, and human settlement of newly emerged islands remain poorly constrained. The results of geomorphological and archaeological surveys, combined with calibrated radiocarbon age dates, at Majuro Atoll, Marshall Islands, central Pacific, reveal that the emergence of the island, triggered by a fall in sea level, was quickly followed by human settlement. The elevation of the central body of the island exceeded high water level at 2000 years CalBP, and the complete formation of the island occurred within an interval of 100 years. The island was colonized by people shortly after emergence, at 2000 years CalBP, prior to the establishment of dense vegetation, and has been continuously settled since that time.

Architectural Guidelines for Multimedia and Hypermedia Data Interchange: Computer Aided Acquisition and Logistics Support/Concurrent Engineering (CALS/ CE) and Electronic Commerce/Electronic Data Interchange (EC/EDI)

DTIC Science & Technology

1991-09-01

other networks . 69 For example, E-mail can be sent to an SNA network through a Softswitch gateway, but at a very slow rate. As discussed in Chapter III...10 6. Communication Protocols ..................... 10 D. NEW INFRASTRUCTURES ....................... 11 1. CALS Test Network (CTN...11 2. Industrial Networks ......................... 12 3. FTS-2000 and ISDN ........................ 12 4. CALS Operational Resource

Interactive Computerized Video Orientation.

ERIC Educational Resources Information Center

Briesacker, Jeanie

In response to California State Assembly Bill (AB) 3, which requires the state's community colleges to implement orientations and other specified matriculation services, Fullerton College (FC) developed two orientation videos in 1989 for native speakers of English and English-as-a-Second Language (ESL) students. The videos were used by counselors…

Multi-wavelength properties of two supersoft X-ray sources CAL83 and RXJ0513.9-6951

NASA Astrophysics Data System (ADS)

Rajoelimanana, A.; Meintjes, P.; Charles, P.

2017-10-01

Supersoft X-ray sources (SSS) are highly luminous (˜10^{38} erg s^{-1}), yet low temperature 10^{6} K sources, interpreted as a white dwarf (WD) accreting matter at a very high rate from its (heavy) companion, leading to Eddington-limited, steady hydrogen burning on the WD surface at T˜15-80 eV. A large fraction of this energy irradiates the surface of the disc, which gives rise to a reprocessed flux much larger than the intrinsic disc luminosity, accounting for the large optical and UV fluxes detected in SSS. We present the multi-wavelength properties of two prototypical LMC SSS, CAL83 and RXJ0513.9-6951, with particular emphasis on the anti-correlation between their X-ray and optical behaviour. Our SALT spectra show variable high excitation OVI emission as a function of optical brightness state, and which we link to the cyclic changes in the temperature and size of the WD, and hence the mass accretion rate.

An overview of the CalNex 2010 field mission: research to extend the understanding of climate and air quality issues in California (Invited)

NASA Astrophysics Data System (ADS)

Ryerson, T. B.

2009-12-01

CalNex is a major field study planned for May and June of 2010. The study, led by NOAA and the California Air Resources Board, coordinates many interagency partners with independent but complementary capabilities and goals. Observations from surface-, aircraft-, ship-, and space-based sensors, along with Lagrangian and Eulerian modeling studies, will be used to extend previous studies and contribute new data and understanding to issues relevant to climate change and air quality in California. This overview will present the integrated approach that will be taken in CalNex, utilizing long-term surface observations, instrumented tall towers, several major intensive ground sites, a network of daily ozonesonde launches, a radar profiling network, multiple instrumented research aircraft, a research vessel, and retrievals from several satellites. The primary CalNex science questions and experimental strategies to address them will be presented, with illustrations and data examples taken from recent field projects in California to provide context for the upcoming study.

The NASA Soil Moisture Active Passive (SMAP) Mission - Algorithm and Cal/Val Activities and Synergies with SMOS and Other L-Band Missions

NASA Technical Reports Server (NTRS)

Njoku, Eni; Entekhabi, Dara; O'Neill, Peggy; Jackson, Tom; Kellogg, Kent; Entin, Jared

2011-01-01

NASA's Soil Moisture Active Passive (SMAP) mission, planned for launch in late 2014, has as its key measurement objective the frequent, global mapping of near-surface soil moisture and its freeze-thaw state. SMAP soil moisture and freeze/thaw measurements at 10 km and 3 km resolutions respectively, would enable significantly improved estimates of water, energy and carbon transfers between the land and atmosphere. Soil moisture control of these fluxes is a key factor in the performance of atmospheric models used for weather forecasts and climate projections Soil moisture measurements are also of great importance in assessing floods and for monitoring drought. In addition, observations of soil moisture and freeze/thaw timing over the boreal latitudes can help reduce uncertainties in quantifying the global carbon balance. The SMAP measurement concept utilizes an L-band radar and radiometer sharing a rotating 6-meter mesh reflector antenna. The SMAP radiometer and radar flight hardware and ground processing designs are incorporating approaches to identify and mitigate potential terrestrial radio frequency interference (RFI). The radar and radiometer instruments are planned to operate in a 680 km polar orbit, viewing the surface at a constant 40-degree incidence angle with a 1000-km swath width, providing 3-day global coverage. Data from the instruments would yield global maps of soil moisture and freeze/thaw state to be provided at 10 km and 3 km resolutions respectively, every two to three days. Plans are to provide also a radiometer-only soil moisture product at 40-km spatial resolution. This product and the underlying brightness temperatures have characteristics similar to those provided by the Soil Moisture and Ocean Salinity (SMOS) mission. As a result, there are unique opportunities for common data product development and continuity between the two missions. SMAP also has commonalities with other satellite missions having L-band radiometer and/or radar sensors

Graphics Standards in the Computer-Aided Acquisition and Logistic Support (CALS) Program Fiscal Year 1989 Volume 2: MIL-D-28003 Revisions, CGM registration

DTIC Science & Technology

1990-05-01

Naming in CALS U Based on the above rationale and trade studies, including a basic set of trademarked names in the CALS AP should be considered I during a...names for font lists. Based on the various trade studies in this report, including the one on font substitution below the following naming technique...COPYRIGHT SIGN 2/10 -FEMININE ORDINAL INDICATOR I 2/11 LEFT ANGLE QUOTATION MARK 2/12 NOr SIGN 2/13 SOFT HYPHEN 2/14 REGISTERED TRADE MARK SIGN m 2/15

Centromere proteins CENP-C and CAL1 functionally interact in meiosis for centromere clustering, pairing, and chromosome segregation.

PubMed

Unhavaithaya, Yingdee; Orr-Weaver, Terry L

2013-12-03

Meiotic chromosome segregation involves pairing and segregation of homologous chromosomes in the first division and segregation of sister chromatids in the second division. Although it is known that the centromere and kinetochore are responsible for chromosome movement in meiosis as in mitosis, potential specialized meiotic functions are being uncovered. Centromere pairing early in meiosis I, even between nonhomologous chromosomes, and clustering of centromeres can promote proper homolog associations in meiosis I in yeast, plants, and Drosophila. It was not known, however, whether centromere proteins are required for this clustering. We exploited Drosophila mutants for the centromere proteins centromere protein-C (CENP-C) and chromosome alignment 1 (CAL1) to demonstrate that a functional centromere is needed for centromere clustering and pairing. The cenp-C and cal1 mutations result in C-terminal truncations, removing the domains through which these two proteins interact. The mutants show striking genetic interactions, failing to complement as double heterozygotes, resulting in disrupted centromere clustering and meiotic nondisjunction. The cluster of meiotic centromeres localizes to the nucleolus, and this association requires centromere function. In Drosophila, synaptonemal complex (SC) formation can initiate from the centromere, and the SC is retained at the centromere after it disassembles from the chromosome arms. Although functional CENP-C and CAL1 are dispensable for assembly of the SC, they are required for subsequent retention of the SC at the centromere. These results show that integral centromere proteins are required for nuclear position and intercentromere associations in meiosis.

E-Commerce May Help Colleges Cut Costs and Paperwork.

ERIC Educational Resources Information Center

Olsen, Florence

2000-01-01

Describes the increasing trend of incorporating electronic commerce methods to purchasing systems at colleges and universities. Provides examples from the University of Pennsylvania, Harvard University (Massachusetts), California State University at Fullerton, and the University of California at Los Angeles. (DB)

Characterization of emissions sources in the California-Mexico Border Region during Cal-Mex 2010

NASA Astrophysics Data System (ADS)

Zavala, M. A.; Lei, W.; Li, G.; Bei, N.; Barrera, H.; Tejeda, D.; Molina, L. T.; Cal-Mex 2010 Emissions Team

2010-12-01

The California-Mexico border region provides an opportunity to evaluate the characteristics of the emission processes in rapidly expanding urban areas where intensive international trade and commerce activities occur. Intense anthropogenic activities, biomass burning, as well as biological and geological sources significantly contribute to high concentration levels of particulate matter (PM), polycyclic aromatic hydrocarbons (PAHs), nitrogen oxides (NOx), volatile organic compounds (VOCs), air toxics, and ozone observed in the California-US Baja California-Mexico border region. The continued efforts by Mexico and US for improving and updating the emissions inventories in the sister cities of San Diego-Tijuana and Calexico-Mexicali has helped to understand the emission processes in the border region. In addition, the recent Cal-Mex 2010 field campaign included a series of measurements aimed at characterizing the emissions from major sources in the California-Mexico border region. In this work we will present our analyzes of the data obtained during Cal-Mex 2010 for the characterization of the emission sources and their use for the evaluation of the recent emissions inventories for the Mexican cities of Tijuana and Mexicali. The developed emissions inventories will be implemented in concurrent air quality modeling efforts for understanding the physical and chemical transformations of air pollutants in the California-Mexico border region and their impacts.

Impact of climate variability on terrestrial environment in Western Europe between 45 and 9 kyr cal. BP: vegetation dynamics recorded by the Bergsee Lake (Black Forest, Germany).

NASA Astrophysics Data System (ADS)

Duprat-Oualid, Fanny; Begeot, Carole; Rius, Damien; Millet, Laurent; Magny, Michel

2016-04-01

Between 9 and 45 kyr cal. BP, two great transitions lead the global climate system to evolve from the Last-Glacial period (115-14.7 kyr cal. BP), to two successive warmer periods, the Late-Glacial Interstadial (14.7-11.7 kyr cal. BP) and the Holocene (11.7-0 kyr cal. BP). δ18O variations recorded in Greenland ice cores (GRIP & NGRIP) revealed high frequency climate variability within the Last Glacial. These reference isotopic records highlighted a succession of centennial-to-millennial warm/cold events, the so-called Greenland Interstadials (GI) and Greenland Stadials (GS). The number continental records about the period 14.7-0 kyr cal. BP is substantial. This allowed to understand the vegetation dynamics in response to climate changes this period at the North-Atlantic scale. However, sequences covering the glacial period (beyond 20 kyr cal.BP) remain rare, because of hiatuses mostly due to local glaciers. Therefore, sedimentary continuous records of vegetation dynamics are still needed to better understand climate changes during the Last Glacial in Western Europe (Heiri et al. 2014). Here we present a new high-resolution pollen record from Lake Bergsee (47°34'20''N, 7°56'11''E, 382 m a.s.l). This lake is located south of Black Forest and north of the Alps, beyond the zone of glaciers maximal extension. Therefore it could have recorded the whole last climatic cycle, i.e. 120-0 kyr cal. BP. In 2013, a 29 m long core was extracted from the Bergsee. According to the depth-age model based on 14C AMS dating and the Laacher See Tephra (LST), the record spans continuously at least the last 45 kyrs. The first series of pollen analysis, focused on the 45-9 kyr cal. BP time window, allows us to reconstruct a precise, faithful and continuous vegetation history at the centennial scale. This high temporal resolution enabled to assess the response of vegetation to secular climate events (e.g. GI-4 = 200 yrs). First, our results show that vegetation responded to climate

TREAT Neutronics Analysis and Design Support, Part II: Multi-SERTTA-CAL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bess, John D.; Woolstenhulme, Nicolas E.; Hill, Connie M.

2016-08-01

Experiment vehicle design is necessary in preparation for Transient Reactor Test (TREAT) facility restart and the resumption of transient testing to support Accident Tolerant Fuel (ATF) characterization and other future fuels testing requirements. Currently the most mature vehicle design is the Multi-SERTTA (Static Environments Rodlet Transient Test Apparatuses), which can accommodate up to four concurrent rodlet-sized specimens under separate environmental conditions. Robust test vehicle design requires neutronics analyses to support design development, optimization of the power coupling factor (PCF) to efficiently maximize energy generation in the test fuel rodlets, and experiment safety analyses. In integral aspect of prior TREAT transientmore » testing was the incorporation of calibration experiments to experimentally evaluate and validate test conditions in preparation of the actual fuel testing. The calibration experiment package established the test parameter conditions to support fine-tuning of the computational models to deliver the required energy deposition to the fuel samples. The calibration vehicle was designed to be as near neutronically equivalent to the experiment vehicle as possible to minimize errors between the calibration and final tests. The Multi-SERTTA-CAL vehicle was designed to serve as the calibration vehicle supporting Multi-SERTTA experimentation. Models of the Multi-SERTTA-CAL vehicle containing typical PWR-fuel rodlets were prepared and neutronics calculations were performed using MCNP6.1 with ENDF/B-VII.1 nuclear data libraries; these results were then compared against those performed for Multi-SERTTA to determine the similarity and possible design modification necessary prior to construction of these experiment vehicles. The estimated reactivity insertion worth into the TREAT core is very similar between the two vehicle designs, with the primary physical difference being a hollow Inconel tube running down the length of the

Direct pulp capping in primary molars using a resin-modified Portland cement-based material (TheraCal) compared to MTA with 12-month follow-up: a randomised clinical trial.

PubMed

Erfanparast, L; Iranparvar, P; Vafaei, A

2018-05-16

This study was to compare the success of resin-modified Portland cement-based material (TheraCal) with MTA in direct pulp capping (DPC) of primary molars. Symmetrical bilateral primary molars (92) from 46 healthy subjects aged 5-7 years were included in this split-mouth randomised clinical trial. DPC for small non-contaminated pulp exposures using either TheraCal or MTA were randomly performed in symmetrical molars. Thereafter, teeth were restored with amalgam. Clinical and radiographic evaluations were performed at 6 and 12 month follow-ups. Data were analysed using Chi square test at a significance level of 0.05. At the final follow-up session 74 teeth were available. After 12 months, the overall success rates for MTA and TheraCal were 94.5 and 91.8%, respectively. The difference between outcomes of the two groups was not statistically significant (P > 0.05). Within the limitations of the current study, radiographic and clinical findings revealed that TheraCal exhibited a comparable outcome to MTA in DPC of primary molars after 12 months.

The 2010 California Research at the Nexus of Air Quality and Climate Change (CalNex) field study

NASA Astrophysics Data System (ADS)

Ryerson, T. B.; Andrews, A. E.; Angevine, W. M.; Bates, T. S.; Brock, C. A.; Cairns, B.; Cohen, R. C.; Cooper, O. R.; de Gouw, J. A.; Fehsenfeld, F. C.; Ferrare, R. A.; Fischer, M. L.; Flagan, R. C.; Goldstein, A. H.; Hair, J. W.; Hardesty, R. M.; Hostetler, C. A.; Jimenez, J. L.; Langford, A. O.; McCauley, E.; McKeen, S. A.; Molina, L. T.; Nenes, A.; Oltmans, S. J.; Parrish, D. D.; Pederson, J. R.; Pierce, R. B.; Prather, K.; Quinn, P. K.; Seinfeld, J. H.; Senff, C. J.; Sorooshian, A.; Stutz, J.; Surratt, J. D.; Trainer, M.; Volkamer, R.; Williams, E. J.; Wofsy, S. C.

2013-06-01

The California Research at the Nexus of Air Quality and Climate Change (CalNex) field study was conducted throughout California in May, June, and July of 2010. The study was organized to address issues simultaneously relevant to atmospheric pollution and climate change, including (1) emission inventory assessment, (2) atmospheric transport and dispersion, (3) atmospheric chemical processing, and (4) cloud-aerosol interactions and aerosol radiative effects. Measurements from networks of ground sites, a research ship, tall towers, balloon-borne ozonesondes, multiple aircraft, and satellites provided in situ and remotely sensed data on trace pollutant and greenhouse gas concentrations, aerosol chemical composition and microphysical properties, cloud microphysics, and meteorological parameters. This overview report provides operational information for the variety of sites, platforms, and measurements, their joint deployment strategy, and summarizes findings that have resulted from the collaborative analyses of the CalNex field study. Climate-relevant findings from CalNex include that leakage from natural gas infrastructure may account for the excess of observed methane over emission estimates in Los Angeles. Air-quality relevant findings include the following: mobile fleet VOC significantly declines, and NOx emissions continue to have an impact on ozone in the Los Angeles basin; the relative contributions of diesel and gasoline emission to secondary organic aerosol are not fully understood; and nighttime NO3 chemistry contributes significantly to secondary organic aerosol mass in the San Joaquin Valley. Findings simultaneously relevant to climate and air quality include the following: marine vessel emissions changes due to fuel sulfur and speed controls result in a net warming effect but have substantial positive impacts on local air quality.

Partners in Success for Young Adolescents: The Cal Ripken, Sr. Foundation and National Middle School Association

ERIC Educational Resources Information Center

Chan, Janice

2007-01-01

Middle school students are at a critical point in their lives. One way or another they are learning the decision-making and coping skills that they will use as adults. To be successful they need guidance from caring teachers, parents, coaches, and other significant adults who are positive role models. For Cal Ripken, Jr. and his brother Bill, it…

The short form of the recombinant CAL-A-type lipase UM03410 from the smut fungus Ustilago maydis exhibits an inherent trans-fatty acid selectivity.

PubMed

Brundiek, Henrike; Saß, Stefan; Evitt, Andrew; Kourist, Robert; Bornscheuer, Uwe T

2012-04-01

The Ustilago maydis lipase UM03410 belongs to the mostly unexplored Candida antarctica lipase (CAL-A) subfamily. The two lipases with [corrected] the highest identity are a lipase from Sporisorium reilianum and the prototypic CAL-A. In contrast to the other CAL-A-type lipases, this hypothetical U. maydis lipase is annotated to possess a prolonged N-terminus of unknown function. Here, we show for the first time the recombinant expression of two versions of lipase UM03410: the full-length form (lipUMf) and an Nterminally truncated form (lipUMs). For comparison to the prototype, the expression of recombinant CAL-A in E. coli was investigated. Although both forms of lipase UM03410 could be expressed functionally in E. coli, the N-terminally truncated form (lipUMs) demonstrated significantly higher activities towards p-nitrophenyl esters. The functional expression of the N-terminally truncated lipase was further optimized by the appropriate choice of the E. coli strain, lowering the cultivation temperature to 20 °C and enrichment of the cultivation medium with glucose. Primary characteristics of the recombinant lipase are its pH optimum in the range of 6.5-7.0 and its temperature optimum at 55 °C. As is typical for lipases, lipUM03410 shows preference for long chain fatty acid esters with myristic acid ester (C14:0 ester) being the most preferred one.More importantly, lipUMs exhibits an inherent preference for C18:1Δ9 trans and C18:1Δ11 trans-fatty acid esters similar to CAL-A. Therefore, the short form of this U. maydis lipase is the only other currently known lipase with a distinct trans-fatty acid selectivity.

Chronostratigraphy in karst records from the Epipaleolithic to the Mid/Early Neolithic (c. 13.0-6.0 cal ka BP) in the Catalan Coastal Ranges of NE Iberia: environmental changes, sedimentary processes and human activity

NASA Astrophysics Data System (ADS)

Bergadà, M. Mercè; Cervelló, Josep M.; Edo, Manel; Cebrià, Artur; Oms, F. Xavier; Martínez, Pablo; Antolín, Ferran; Morales, Juan Ignacio; Pedro, Mireia

2018-03-01

The stratigraphic, sedimentary and palaeoenvironmental features reflected in cavities in the Catalan Coastal Ranges of NE Iberia (Can Sadurní and Guineu caves) characterize the periods of pronounced climatic and human complexity that occurred c. 13.0-6.0 cal ka BP. This includes the stages of the Younger Dryas and Mid/Early Holocene, the latter being one of the periods of so-called Rapid Climatic Changes (RCCs). These caves, like others in Mediterranean contexts, are the result of an old duct originating in the saturated zone of the karst system and open to the outside; recording a succession of different detrital and anthropic episodes of the Epipaleolithic, Mesolithic and Neolithic communities. From this study it can be seen that paleoclimatic events do not always present clear signals in the karst records, especially c. 12.7-7.4 cal ka BP, corresponding to the Epipaleolithic and Mesolithic. It is characterized by a stratigraphic discontinuity in which there are phases with predominantly detrital sedimentation alternating with hiatus intervals. Detrital sedimentation formed by fine material colluvium with gravitational movements or solifluction processes in fresh and humid conditions. It appears in the following chronological intervals: 12.7-12.2 cal ka BP, 11.5/11.1-10.7/10.4 cal ka BP and 8.2-8.0 cal ka BP (less humid). Hiatus phases are represented in the rest of the sequence up to c. 7.4 cal ka BP. From the sedimentary point of view these stages of hiatus are indicative of phases of stability or lack of episodes with seasonal contrasts; a fact that would cause interruptions to detrital deposition in the interior of the caves. In contrast, in the period c. 7.4 to 6.0 cal ka BP, attributed to the Middle and Early Neolithic, there is a certain stratigraphic continuity. From the sedimentary point of view it is distinguished by a variability of processes that responds to accumulative episodes of short duration characteristic of morphogenesis of the slopes in an

Energy, Sustainability, Collaboration: Learning it, Teaching it, and Living it -- At Cal Poly, in Guatemala, and at Home

NASA Astrophysics Data System (ADS)

Schwartz, Pete

2012-11-01

Three questions have become important to me: *``What is the future of our energy dilemma, and how can I participate toward a solution?'' Since 2007, I have been teaching ``Energy, Society, and the Environment'' at Cal Poly as well as developing and analyzing renewable energy technologies. In the process I have learned as much as my students. This interest was initially sparked by making ``sustainable'' changes to my home and lifestyle, and has since fueled constant domestic experimentation. *The above question extends to ``Environmental Justice'', which is essentially a question of ``who benefits and who suffers as a result of our societal choices?'' For the past three years, I've developed and directed a collaborative (Guatemalan/Cal Poly) appropriate technology field school. Students from both countries learn together during the two-month summer program in a small mountain village in Guatemala (www.guateca.com). *``What happens to learning efficacy when students become friends?'' For the past three years, I've been actively engaged with a group of Cal Poly instructors in a quest to create community in the learning environment (www.sustainslo.org). Additionally, I've begun to teach all my classes ``inside out'', consistent with the advice of Physics Nobel Prize Laureate Carl Weiman (Science, 13 May 2011, VOL 332 862 -- 864). Students learn the material at home by reading or watching videos available on the web. This opens up class time for guided discussion, experimentation, and calculations. The Guateca field school provides an extreme example of this principle, as all the students do become friends. with very interesting results.

Lateglacial vegetation dynamics in the eastern Baltic region between 14,500 and 11,400 cal yr BP: A complete record since the Bølling (GI-1e) to the Holocene

NASA Astrophysics Data System (ADS)

Veski, Siim; Amon, Leeli; Heinsalu, Atko; Reitalu, Triin; Saarse, Leili; Stivrins, Normunds; Vassiljev, Jüri

2012-04-01

This paper discusses a complete record of vegetation history since the Bølling (GI-1e) warming (14,500 cal yr BP) up to the Holocene in Latvia. To date, this is the only complete record of such age in the eastern Baltic area and the northernmost area for which Bølling records are present. Combining pollen evidence, pollen accumulation rates (PAR) and plant macrofossil data, we assess the local and regional vegetation development, and we attempt to separate the true Lateglacial vegetation signal by removing the obviously redeposited thermophilous pollen; however, we remove not only their signal, we discuss the possibilities of separating the redeposition signal of the so-called "local Lateglacial trees", pine and birch, by looking at their corrosion and degradation. The results show that the Bølling warming in the eastern Baltic area was a treeless tundra community consisting of the shrubs Betula nana, Dryas octopetala and Salix polaris. The Older Dryas cold spell is clearly recognised as a decline in the total concentration of plant macrofossils and PARs at between 14,200 and 13,500 cal yr BP. At 13,460 cal yr BP, the B. nana macrofossils disappear, and tree birch (Betula sect. Albae) appears, marking the start of tree birch forest. The presence of pine forest is confirmed by a variety of macrofossils, including bark, wood, needles and seeds, since 13,400 cal yr BP, at the same time at which pine stomata are found. The first identified pine stomata finds are associated with a Pinus PAR over 3000 grains cm-2 yr-1 and pine macrofossil finds with a Pinus PAR over 4000 grains cm-2 yr-1. During the warmest period of the GI-1a (Allerød) at 13,000-12,700 cal yr BP, a pine forest with deciduous trees (birch -Betula pendula and aspen -Populus tremula) developed in the study area. The Younger Dryas (GS-1) cooling strongly affected the floral composition in eastern Latvia. The PAR of the tree taxa declined abruptly from a maximum value at 12,700 to below 1000 grains cm-2

Teachers' Perceptions on the Use of ICT in a CAL Environment to Enhance the Conception of Science Concepts

ERIC Educational Resources Information Center

George, Frikkie; Ogunniyi, M.

2016-01-01

Instructional methodologies increasingly require teachers' efficacy and implementation of computer-assisted learning (CAL) practices in general and particularly in the science classroom. The South African National Education Department's e-Education[1] policy also encourages the use of computers and computer software in implementing outcome-based…

A 27cal ka biomarker-based record of ecosystem changes from lacustrine sediments of the Chihuahua Desert of Mexico

NASA Astrophysics Data System (ADS)

Chávez-Lara, C. M.; Holtvoeth, J.; Roy, P. D.; Pancost, R. D.

2018-07-01

Hydroclimate variation of the northwest Mexico during the late Pleistocene and Holocene is an active area of debate, with uncertainty in the nature and sources of precipitation. Previous research has inferred the influences of winter storms, summer monsoonal rain and autumn tropical cyclones. The impacts on regional and local ecosystems, however, are not well constrained. Here, we investigate the response of lacustrine and terrestrial habitats of the Santiaguillo Basin in the Chihuahua Desert (Mexico) to hydrological changes occurring since the late last glacial. Biomarkers from the sediments reflect variable input of organic matter (OM) from algal and bacterial biomass, aquatic microfauna and surrounding vegetation, revealing distinct stages of ecosystem adaption over the last 27 cal ka. Based on previously published and new data, we show that a perennial productive lake was present during the late glacial and it persisted until 17.5 cal ka BP. Coinciding with Heinrich event 1, OM supply from deteriorating wetland soils may have been caused by early dry conditions. Further phases of increasing aridity and a shrinking water body drove changing OM quality and biomarker composition during the early and mid-Holocene. A pronounced shift in biomarker distributions at 4 cal ka BP suggests that the supply of plant litter from resinous trees and grasses increased, likely reflecting the establishment of modern vegetation. Our results illustrate the potential of biomarker applications in the area, adding to the evidence of hydroclimate variability and enabling reconstructions of local ecosystem dynamics.

Teaching from the Web: Constructing a Library Learning Environment Where Connections Can Be Made.

ERIC Educational Resources Information Center

Cox, Suellen; Housewright, Elizabeth

2001-01-01

Describes a course developed by librarians at California State University, Fullerton as an introduction to information technology for freshmen students. Topics include collaboration and feedback from team teaching; formal assessment and student evaluation;, and the increasing use of Web-based resources and technology. (Author/LRW)

Black Carbon Emissions from In-use Ships: Results from CalNex 2010

NASA Astrophysics Data System (ADS)

Buffaloe, Gina Marise

Black carbon (BC) mass emission factors (EFBC; g-BC (kg-fuel)--1) from a variety of ocean going vessels have been determined from measurements of BC and CO2 concentrations in ship plumes intercepted by the R/V Atlantis during the 2010 California Nexus (CalNex) campaign. The ships encountered were all operating within 24 nautical miles of the California coast and were utilizing relatively low sulphur fuels. Black carbon concentrations within the plumes, from which EFBC values are determined, were measured using four independent instruments: a photoacoustic spectrometer and a particle soot absorption photometer, which measure light absorption, and a single particle soot photometer and soot particle aerosol mass spectrometer, which measure the mass concentration of refractory BC directly. The measured EFBC have been divided into vessel type categories and engine type categories, from which averages have been determined. The geometric average EFBC, determined from over 71 vessels and 135 plumes encountered, was 0.31 g-BC (kg-fuel)--1. The most frequent engine type encountered was the slow speed diesel (SSD), and the most frequent SSD vessel type was the cargo ship sub-category. Average and median EF BC values from these two categories are compared to previous observations from the Texas Air Quality Study (TexAQS) in 2006, in which the ships encountered were predominately operating high sulphur fuels. There is some indication that the EFBC values for SSD vessels during CalNex were lower than during TexAQS, although ship-to-ship variability in these data sets makes it difficult to draw firm conclusions about the influence of fuel quality on EFBC.

Late Holocene vegetation and fire dynamics from a savanna-forest ecotone in Roraima state, northern Brazilian Amazon

NASA Astrophysics Data System (ADS)

da Silva Meneses, Maria Ecilene Nunes; da Costa, Marcondes Lima; Behling, Hermann

2013-03-01

Two sediment cores from Mauritia flexuosa palm swamps have been studied by pollen and charcoal analysis. The cores Fazenda Cigana (FC) and Terra Indígena Aningal (TIA) were taken from a savanna-forest ecotone area in the Roraima State, northern Brazilian Amazon. Based on 5 radiocarbon dates, these records allow the reconstruction of the vegetation fire and climate dynamics during the past 1550 years. At the FC site was recorded a higher proportion of forest cover, suggesting local wetter climatic conditions favorable for forest expansion, especially by gallery forests, between 1550 and 1400 cal yr BP. Stands of M. flexuosa started to establish on the site indicating sufficient soil moisture. From 1400 to 1050 cal yr BP, forest cover retreated while savanna, and the Mauritia palm swamp expanded considerably. The FC site was marked by savanna and Mauritia cover with a slight increase of forest between ca. 1050 and 900 cal yr BP. From 900 to 300 cal yr BP the savanna and palm swamp taxa became dominant and the forest area decreased. At the TIA site the savanna cover was dominant between 1200 and 1000 cal yr BP. From 1000 to 700 forest expanded while savanna and Mauritia palm swamp reduced. Between 700 and 300 cal yr BP savanna and Mauritia palm swamp increased and forest area decreased. The high amount of charred particles found in the sediments, indicate fires with a marked increase between 1400 to 1000 cal yr BP (FC site) and 700 to 300 cal yr BP (TIA site), and probably caused the retreat of forest cover during these two time intervals. The relatively lower fire activity after 300 cal yr BP until present-day favored the increase of forested area at both TIA and FC sites. The arrival of the European settler and the subsequent introduction of cattle, is suggested as the main reason for the decrease of fire in the study region. The results point the fire caused by indigenous people as the principal controlling factor for forest and savanna dynamics during the past

CalA, a Cyanobacterial AbrB Protein, Interacts with the Upstream Region of hypC and Acts as a Repressor of Its Transcription in the Cyanobacterium Nostoc sp. Strain PCC 7120▿ †

PubMed Central

Agervald, Åsa; Zhang, Xiaohui; Stensjö, Karin; Devine, Ellenor; Lindblad, Peter

2010-01-01

The filamentous, heterocystous, nitrogen-fixing cyanobacterium Nostoc sp. strain PCC 7120 may contain, depending on growth conditions, up to two hydrogenases directly involved in hydrogen metabolism. HypC is one out of at least seven auxiliary gene products required for synthesis of a functional hydrogenase, specifically involved in the maturation of the large subunit. In this study we present a protein, CalA (Alr0946 in the genome), belonging to the transcription regulator family AbrB, which in protein-DNA assays was found to interact with the upstream region of hypC. Transcriptional investigations showed that calA is cotranscribed with the downstream gene alr0947, which encodes a putative protease from the abortive infection superfamily, Abi. CalA was shown to interact specifically not only with the upstream region of hypC but also with its own upstream region, acting as a repressor on hypC. The bidirectional hydrogenase activity was significantly downregulated when CalA was overexpressed, demonstrating a correlation with the transcription factor, either direct or indirect. In silico studies showed that homologues to both CalA and Alr0947 are highly conserved proteins within cyanobacteria with very similar physical organizations of the corresponding structural genes. Possible functions of the cotranscribed downstream protein Alr0947 are presented. In addition, we present a three-dimensional (3D) model of the DNA binding domain of CalA and putative DNA binding mechanisms are discussed. PMID:20023111

Multistep food plant processing at Grotta Paglicci (Southern Italy) around 32,600 cal B.P.

PubMed Central

Mariotti Lippi, Marta; Foggi, Bruno; Aranguren, Biancamaria; Ronchitelli, Annamaria; Revedin, Anna

2015-01-01

Residue analyses on a grinding tool recovered at Grotta Paglicci sublayer 23A [32,614 ± 429 calibrated (cal) B.P.], Southern Italy, have demonstrated that early modern humans collected and processed various plants. The recording of starch grains attributable to Avena (oat) caryopses expands our information about the food plants used for producing flour in Europe during the Paleolithic and about the origins of a food tradition persisting up to the present in the Mediterranean basin. The quantitative distribution of the starch grains on the surface of the grinding stone furnished information about the tool handling, confirming its use as a pestle-grinder, as suggested by the wear-trace analysis. The particular state of preservation of the starch grains suggests the use of a thermal treatment before grinding, possibly to accelerate drying of the plants, making the following process easier and faster. The study clearly indicates that the exploitation of plant resources was very important for hunter–gatherer populations, to the point that the Early Gravettian inhabitants of Paglicci were able to process food plants and already possessed a wealth of knowledge that was to become widespread after the dawn of agriculture. PMID:26351674

Multistep food plant processing at Grotta Paglicci (Southern Italy) around 32,600 cal B.P.

PubMed

Mariotti Lippi, Marta; Foggi, Bruno; Aranguren, Biancamaria; Ronchitelli, Annamaria; Revedin, Anna

2015-09-29

Residue analyses on a grinding tool recovered at Grotta Paglicci sublayer 23A [32,614 ± 429 calibrated (cal) B.P.], Southern Italy, have demonstrated that early modern humans collected and processed various plants. The recording of starch grains attributable to Avena (oat) caryopses expands our information about the food plants used for producing flour in Europe during the Paleolithic and about the origins of a food tradition persisting up to the present in the Mediterranean basin. The quantitative distribution of the starch grains on the surface of the grinding stone furnished information about the tool handling, confirming its use as a pestle-grinder, as suggested by the wear-trace analysis. The particular state of preservation of the starch grains suggests the use of a thermal treatment before grinding, possibly to accelerate drying of the plants, making the following process easier and faster. The study clearly indicates that the exploitation of plant resources was very important for hunter-gatherer populations, to the point that the Early Gravettian inhabitants of Paglicci were able to process food plants and already possessed a wealth of knowledge that was to become widespread after the dawn of agriculture.

Web-Enabled Systems for Student Access.

ERIC Educational Resources Information Center

Harris, Chad S.; Herring, Tom

1999-01-01

California State University, Fullerton is developing a suite of server-based, Web-enabled applications that distribute the functionality of its student information system software to external customers without modifying the mainframe applications or databases. The cost-effective, secure, and rapidly deployable business solution involves using the…

Quien Soy? Finding My Place in History: Personalizing Learning through Faculty/Librarian Collaboration

ERIC Educational Resources Information Center

Hein, Nancy Porras; Miller, Barbara A.

2004-01-01

Using an authentic assessment approach, two California State University, Fullerton, faculty members developed instructional strategies in support of an assignment that requires students to situate their families within a historical framework. We describe our efforts to provide students with the research skills to successfully complete the…

Country Information Available in Government Documents.

ERIC Educational Resources Information Center

Richey, Debora J., Comp.

This annotated bibliography lists federal and international documents at the library of California State University at Fullerton which provide information on foreign countries. Documents are organized under the following subject headings: (1) general information; (2) aging; (3) agriculture/food supply and consumption; (4) children; (5) civil…

The Intersectionality of Gender and Race--Programs to Support Men of Color in Education

ERIC Educational Resources Information Center

Person, Dawn; Dawson, Robert; García, Yvonne; Jones, Andrew

2017-01-01

This chapter reports on three research studies conducted by the Center for Research on Educational Access and Leadership (C-REAL) at California State University, Fullerton (CSUF) that are designed to help higher education institutions enhance their practices in serving men of color, namely Black and Latino men.

Arboviral disease--United States, 1994.

PubMed

1995-09-08

Arboviruses are mosquitoborne and tickborne agents that persist in nature in complex cycles involving birds and mammals, including humans. Characteristics of arboviral infection include fever, headache, encephalitis, and sometimes death. In 1994, health departments in 20 states reported 100 presumptive or confirmed human cases of arboviral disease to CDC. Of these, 76 were California (CAL) serogroup encephalitis; 20, St. Louis encephalitis (SLE); two, western equine encephalomyelitis (WEE); one, eastern equine encephalomyelitis (EEE); and one, Powassan encephalitis (POW). This report summarizes information about arboviral disease in the United States during 1994.

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27).

PubMed

Celińska-Janowicz, Katarzyna; Zaręba, Ilona; Lazarek, Urszula; Teul, Joanna; Tomczyk, Michał; Pałka, Jerzy; Miltyk, Wojciech

2018-01-01

Propolis evokes several therapeutic properties, including anticancer activity. These activities are attributed to the action of polyphenols. Previously it has been demonstrated, that one of the most abundant polyphenolic compounds in ethanolic extracts of propolis are chrysin, caffeic acid, p -coumaric acid, and ferulic acid. Although their pro-apoptotic activity on human tongue squamous cell carcinoma cells (CAL-27) was established previously, the detailed mechanism of this process remains unclear. Considering the crucial role of proline metabolism and proline dehydrogenase/proline oxidase (PRODH/POX) in the regulation of cancer cell survival/apoptosis, we studied these processes in polyphenol-treated CAL-27 cells. All studied polyphenols evoked anti-proliferative activity, accompanied by increased PRODH/POX, P53, active caspases-3 and -9 expressions and decreased collagen biosynthesis, prolidase activity and proline concentration in CAL-27 cells. These data suggest that polyphenols of propolis induce PRODH/POX-dependent apoptosis through up-regulation of mitochondrial proline degradation and down-regulation of proline utilization for collagen biosynthesis.

Constituents of Propolis: Chrysin, Caffeic Acid, p-Coumaric Acid, and Ferulic Acid Induce PRODH/POX-Dependent Apoptosis in Human Tongue Squamous Cell Carcinoma Cell (CAL-27)

PubMed Central

Celińska-Janowicz, Katarzyna; Zaręba, Ilona; Lazarek, Urszula; Teul, Joanna; Tomczyk, Michał; Pałka, Jerzy; Miltyk, Wojciech

2018-01-01

Propolis evokes several therapeutic properties, including anticancer activity. These activities are attributed to the action of polyphenols. Previously it has been demonstrated, that one of the most abundant polyphenolic compounds in ethanolic extracts of propolis are chrysin, caffeic acid, p-coumaric acid, and ferulic acid. Although their pro-apoptotic activity on human tongue squamous cell carcinoma cells (CAL-27) was established previously, the detailed mechanism of this process remains unclear. Considering the crucial role of proline metabolism and proline dehydrogenase/proline oxidase (PRODH/POX) in the regulation of cancer cell survival/apoptosis, we studied these processes in polyphenol-treated CAL-27 cells. All studied polyphenols evoked anti-proliferative activity, accompanied by increased PRODH/POX, P53, active caspases-3 and -9 expressions and decreased collagen biosynthesis, prolidase activity and proline concentration in CAL-27 cells. These data suggest that polyphenols of propolis induce PRODH/POX-dependent apoptosis through up-regulation of mitochondrial proline degradation and down-regulation of proline utilization for collagen biosynthesis. PMID:29681859

Constraints on primary and secondary particulate carbon sources using chemical tracer and 14C methods during CalNex-Bakersfield

EPA Science Inventory

The present study investigates primary and secondary sources of organic carbon for Bakersfield, CA, USA as part of the 2010 CalNex study. The method used here involves integrated sampling that is designed to allow for detailed and specific chemical analysis of particulate matter ...

The 3000-4000 cal. BP anthropogenic shift in fire regime in the French Pyrenees.

NASA Astrophysics Data System (ADS)

Rius, D.; Vannière, B.; Galop, D.; Richard, H.

2009-04-01

Fire is a key disturbing agent in a wide range of ecosystems: boreal biome (Pitkanen, 2000), Mediterranean area (Colombaroli et al., 2008) as well as temperate European mountain zones (Tinner et al., 1999). During the Holocene, climate may control fire regime by both ignition and fire spread-favouring conditions (i.e. composition, structure and moisture of biomass) whereas man may change charcoal accumulation patterns through type and intensity of agro-pastoral activities. In western and Mediterranean Europe, single sites charcoal analysis recorded the anthropogenic forcing over fire regime broadly between the mid and the late-Holocene. Turner et al (2008) showed that climate and fire had been disconnected since 1700 cal. BP in Turkey. In central Swiss, Mean Fire Interval decreased by two times 2000 years ago due to increasing human impact (Stahli et al., 2006). In Italy, climate and man have had a combined influence on fire-hazard since ca 4000 cal. BP (Vannière et al., 2008). In the Pyrenees Mountains, the linkage between agro-pastoral practices and fire could be dated back to ca 4000-3000 cal. BP with a clear succession of a clearance phase (high fire frequency) followed by a quite linear trend throughout Middle Ages and Modern times corresponding to a change in fire use (Vanniere et al., 2001; Galop et al., 2002, Rius et al., in press). The quantification of fire regimes parameters such as frequency with robust methodological tools (Inferred Fire Frequency, Mean Fire Interval) is needed to understand and characterise such shifts. Here we present two sequences from the Lourdes basin (col d'Ech peat bog) and from the occidental Pyrenees (Gabarn peat bog), which cover the last 9000 years with high temporal resolution. The main goals of this study were to (1) assess control factors of fire regime throughout the lateglacial and Holocene (climate and/or man) on the local scale, (2) evidence the local/regional significance of these control factors , (3) discuss the

RVC-CAL library for endmember and abundance estimation in hyperspectral image analysis

NASA Astrophysics Data System (ADS)

Lazcano López, R.; Madroñal Quintín, D.; Juárez Martínez, E.; Sanz Álvaro, C.

2015-10-01

Hyperspectral imaging (HI) collects information from across the electromagnetic spectrum, covering a wide range of wavelengths. Although this technology was initially developed for remote sensing and earth observation, its multiple advantages - such as high spectral resolution - led to its application in other fields, as cancer detection. However, this new field has shown specific requirements; for instance, it needs to accomplish strong time specifications, since all the potential applications - like surgical guidance or in vivo tumor detection - imply real-time requisites. Achieving this time requirements is a great challenge, as hyperspectral images generate extremely high volumes of data to process. Thus, some new research lines are studying new processing techniques, and the most relevant ones are related to system parallelization. In that line, this paper describes the construction of a new hyperspectral processing library for RVC-CAL language, which is specifically designed for multimedia applications and allows multithreading compilation and system parallelization. This paper presents the development of the required library functions to implement two of the four stages of the hyperspectral imaging processing chain--endmember and abundances estimation. The results obtained show that the library achieves speedups of 30%, approximately, comparing to an existing software of hyperspectral images analysis; concretely, the endmember estimation step reaches an average speedup of 27.6%, which saves almost 8 seconds in the execution time. It also shows the existence of some bottlenecks, as the communication interfaces among the different actors due to the volume of data to transfer. Finally, it is shown that the library considerably simplifies the implementation process. Thus, experimental results show the potential of a RVC-CAL library for analyzing hyperspectral images in real-time, as it provides enough resources to study the system performance.

Computer Support of Operator Training: Constructing and Testing a Prototype of a CAL (Computer Aided Learning) Supported Simulation Environment.

ERIC Educational Resources Information Center

Zillesen, P. G. van Schaick; And Others

Instructional feedback given to the learners during computer simulation sessions may be greatly improved by integrating educational computer simulation programs with hypermedia-based computer-assisted learning (CAL) materials. A prototype of a learning environment of this type called BRINE PURIFICATION was developed for use in corporate training…

Cal State-Long Beach Heeds Call to Investigate Professors' Online Biographies

ERIC Educational Resources Information Center

Bartlett, Thomas

2008-01-01

This article reports that an essay by a film professor at California State University at Long Beach that questions the credentials of his colleagues is stirring controversy on the campus--and sparking investigations. The essay, written by Brian Alan Lane, an associate professor of film, accuses three of his colleagues in the department of film and…

Inquiry-Based Course in Physics and Chemistry for Preservice K-8 Teachers

ERIC Educational Resources Information Center

Loverude, Michael E.; Gonzalez, Barbara L.; Nanes, Roger

2011-01-01

We describe an inquiry-based course in physics and chemistry for preservice K-8 teachers developed at California State University Fullerton. The course is one of three developed primarily to enhance the science content understanding of prospective teachers. The course incorporates a number of innovative instructional strategies and is somewhat…

Those Who Can, Teach.

ERIC Educational Resources Information Center

Barnes, Carol P., Ed.; Goodhue-McWilliams, Kenneth, Ed.

Much of what teachers know about how to teach and how to conceptualize specific academic content is learned from their undergraduate professors. In 1990, California State University, Fullerton, received a grant from the Fund for the Improvement of Postsecondary Education (FIPSE), Project Teach, to improve the quality of instruction which…

Ostracods and sediment geochemistry as indicators of hydrologic and climatic variability in the central part of the Mexican Chihuahuan Desert over the last 27 ka cal BP

NASA Astrophysics Data System (ADS)

Chávez Lara, C. M.; Roy, P. D.; Lozano Santa Cruz, R.; López Balbiaux, N.

2013-12-01

The paleolake Santiaguillo (Durango State) is located in the central part of the Chihuahuan Desert (Mexico). The lacustrine basin covers an area of approximately 1,964 km2 and is surrounded by mountains up to ca. 2,700 masl. This basin was formed by tectonic processes and the basement is formed by volcanic felsic rocks of Tertiary age. Four sediment cores were obtained from central and western part of the basin to reconstruct hydrologic and climate variability during the late Pleistocene and Holocene. In this work, we present paleo-ecology of ostracods and sedimentary geochemistry from two sediment cores (300 cm and 200 cm long) collected from the western basin margin. The age model was constructed from 8 AMS radiocarbon dates and the longest profile represents the last 27 cal ka BP. The ostracode faunal content consists of 4 different species: Limnocythere bradburyi, Cadona patzcuaro, Cypridopsis vidua and Limnocythere ceriotuberosa (listed from highest to lowest abundance) and total abundance varies between 0 and 125 valves/g. Paleo-environmental conditions were reconstructed from the Total Organic Carbon (TOC), Total Inorganic Carbon (TIC), Carbon/Nitrogen ratios (C/N), Chemical Index of Alteration (CIA) and concentrations of Ti, Ca, Si and Al. The results were divided into two zones for interpretation. Zone 1 covers ca. 27-17 cal ka BP (300-191 cm) and is characterized by higher Ti concentrations and above average CIA values. This suggests greater interaction between water and sediment, lower evaporation and relatively higher lake level in the basin. During this interval of higher lakestand, the deposited organic matter was autochthonous (lacustrine origin) and ostracodes suggest presence of a warm and dilute water column (>13 °C and >100 ppm). Sediments of the last 17 cal ka BP (191-0 cm) (Zone 2) are characterized by below average water-sediment interaction, higher carbonate precipitation and deposition of allochthonous organic matter (terrestrial origin

Enhancing Public Resilience to Mass-Casualty WMD Terrorism in the United States: Definitions, Challenges, and Recommendations

DTIC Science & Technology

2010-06-01

please contact: Defense Threat Reduction Agency Advanced Systems and Concepts Office 8725 John J . Kingman Road Ft. Belvoir, VA 22060-6201...familiar settings. Anthony Mawson has found that most flight behavior subsequently characterized as panic is better accounted for as “affiliative...April 2006) 163:667-73. 26 Carol S. Fullerton and Robert J . Ursano, “Psychological and Psychopathological Consequences of Disasters,” in Juan José

Tracing Federal Legislative and Administrative Law.

ERIC Educational Resources Information Center

Richey, Debora

This document is a guide to the basic sources in the California State University, Fullerton, library that may be utilized in tracing federal laws, regulations, and court decisions. The bibliographic citation, library call number and/or location, and description of contents and/or use are provided for each reference source. Several sample entries…

GNSS Radio Occultation Excess Phase Processing with Integrated Uncertainty Estimation for Thermodynamic Cal/Val of Passive Atmospheric Sounders and Climate Science

NASA Astrophysics Data System (ADS)

Innerkofler, J.; Pock, C.; Kirchengast, G.; Schwaerz, M.; Jaeggi, A.; Andres, Y.; Marquardt, C.; Hunt, D.; Schreiner, W. S.; Schwarz, J.

2017-12-01

Global Navigation Satellite System (GNSS) radio occultation (RO) is a highly valuable satellite remote sensing technique for atmospheric and climate sciences, including calibration and validation (cal/val) of passive sounding instruments such as radiometers. It is providing accurate and precise measurements in the troposphere and stratosphere regions with global coverage, long-term stability, and virtually all-weather capability since 2001. For fully exploiting the potential of RO data as a cal/val reference and climate data record, uncertainties attributed to the data need to be assessed. Here we focus on the atmospheric excess phase data, based on the raw occultation tracking and orbit data, and its integrated uncertainty estimation within the new Reference Occultation Processing System (rOPS) developed at the WEGC. These excess phases correspond to integrated refractivity, proportional to pressure/temperature and water vapor, and are therefore highly valuable reference data for thermodynamic cal/val of passive (radiometric) sounder data. In order to enable high accuracy of the excess phase profiles, accurate orbit positions and velocities as well as clock estimates of the GNSS transmitter satellites and RO receiver satellites are determined using the Bernese and Napeos orbit determination software packages. We find orbit uncertainty estimates of about 5 cm (position) / 0.05 mm/s (velocity) for daily orbits for the MetOp, GRACE, and CHAMP RO missions, and decreased uncertainty estimates near 20 cm (position) / 0.2 mm/s (velocity) for the COSMIC RO mission. The strict evaluation and quality control of the position, velocity, and clock accuracies of the daily LEO and GNSS orbits assure smallest achievable uncertainties in the excess phase data. We compared the excess phase profiles from WEGC against profiles from EUMETSAT and UCAR. Results show good agreement in line with the estimated uncertainties, with millimetric differences in the upper stratosphere and

The preparation and photocatalytic activity of CdS/(Cal-Ta2O5-SiO2) composite photocatalyst under visible light

NASA Astrophysics Data System (ADS)

Li, Juxia

2018-02-01

CdS/(Cal-Ta2O5-SiO2) composite photocatalyst has been successfully fabricated via wet chemistry method. Ta2O5-SiO2 with multi-step Ta2O5 deposition on SiO2 has more Ta2O5 on SiO2 to ensure the active sites. Trough multi-step calcination, Ta2O5 can load on SiO2 with uniform and stable, which make it have high photocatalytic activity. The obtained samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), diffuse reflectance ultraviolet-visible spectroscopy (UV-vis) and photoluminescence spectroscopy (PL). Without any co-catalysts, the as-prepared CdS/(Cal-Ta2O5-SiO2) exhibited remarkable photocatalytic activity and recyclability both in the degradation of rhodamine B and in the hydrogen production from water splitting under visible light.

An eLIMA model for the 67 s X-ray periodicity in CAL 83

NASA Astrophysics Data System (ADS)

Odendaal, A.; Meintjes, P. J.

2017-05-01

Supersoft X-ray sources (SSSs) are characterized by their low effective temperatures and high X-ray luminosities. The soft X-ray emission can be explained by hydrogen nuclear burning on the surface of a white dwarf (WD) accreting at an extremely high rate. A peculiar ˜67 s periodicity (P67) was previously discovered in the XMM-Newton light curves of the SSS CAL 83. P67 was detected in X-ray light curves spanning ˜9 yr, but exhibits variability of several seconds on time-scales as short as a few hours, and its properties are remarkably similar to those of dwarf nova oscillations (DNOs). DNOs are short time-scale modulations (≲1 min) often observed in dwarf novae during outburst. DNOs are explained by the well-established low-inertia magnetic accretor (LIMA) model. In this paper, we show that P67 and its associated period variability can be satisfactorily explained by an application of the LIMA model to the more 'extreme' environment in an SSS (eLIMA), contrary to another recent study attempting to explain P67 and its associated variability in terms of non-radial g-mode oscillations in the extended envelope of the rapidly accreting WD in CAL 83. In the eLIMA model, P67 originates in an equatorial belt in the WD envelope at the boundary with the inner accretion disc, with the belt weakly coupled to the WD core by an ˜105 G magnetic field. New optical light curves obtained with the Sutherland High-speed Optical Camera are also presented, exhibiting quasi-periodic modulations on time-scales of ˜1000 s, compatible with the eLIMA framework.

Landscape transformations at the dawn of agriculture in southern Syria (10.7-9.9 ka cal. BP): Plant-specific responses to the impact of human activities and climate change

NASA Astrophysics Data System (ADS)

Arranz-Otaegui, Amaia; López-Sáez, José Antonio; Araus, José Luis; Portillo, Marta; Balbo, Andrea; Iriarte, Eneko; Gourichon, Lionel; Braemer, Frank; Zapata, Lydia; Ibáñez, Juan José

2017-02-01

In southwest Asia, the accelerated impact of human activities on the landscape has often been linked to the development of fully agricultural societies during the middle and late Pre-Pottery Neolithic B (PPNB) period (around 10.2-7.9 ka cal. BP). This work contributes to the debate on the environmental impact of the so-called Neolitisation process by identifying the climatic and anthropogenic factors that contributed to change local and regional vegetation at the time when domesticated plants appeared and developed in southern Syria (around 10.7-9.9 ka cal. BP). In this work a multidisciplinary analysis of plant microremains (pollen and phytoliths) and macroremains (wood charcoal) is carried out along with stable carbon isotope discrimination of wood charcoals in an early PPNB site (Tell Qarassa North, west of the Jabal al-Arab area). Prior to 10.5 ka cal. BP, the results indicate a dynamic equilibrium in the local and regional vegetation, which comprised woodland-steppe, Mediterranean evergreen oak-woodlands, wetland vegetation and coniferous forests. Around 10.5-9.9 ka cal. BP, the elements that regulated the vegetation system changed, resulting in reduced proportions of arboreal cover and the spread of cold-tolerant and wetlands species. Our data show that reinforcing interaction between the elements of the anthropogenic (e.g. herding, fire-related activities) and climatic systems (e.g. temperature, rainfall) contributed to the transformation of early Holocene vegetation during the emergence of fully agricultural societies in southern Syria.

Post-glacial flooding of the Bering Land Bridge dated to 11 cal ka BP based on new geophysical and sediment records

NASA Astrophysics Data System (ADS)

Jakobsson, Martin; Pearce, Christof; Cronin, Thomas M.; Backman, Jan; Anderson, Leif G.; Barrientos, Natalia; Björk, Göran; Coxall, Helen; de Boer, Agatha; Mayer, Larry A.; Mörth, Carl-Magnus; Nilsson, Johan; Rattray, Jayne E.; Stranne, Christian; Semiletov, Igor; O'Regan, Matt

2017-08-01

The Bering Strait connects the Arctic and Pacific oceans and separates the North American and Asian landmasses. The presently shallow ( ˜ 53 m) strait was exposed during the sea level lowstand of the last glacial period, which permitted human migration across a land bridge today referred to as the Bering Land Bridge. Proxy studies (stable isotope composition of foraminifera, whale migration into the Arctic Ocean, mollusc and insect fossils and paleobotanical data) have suggested a range of ages for the Bering Strait reopening, mainly falling within the Younger Dryas stadial (12.9-11.7 cal ka BP). Here we provide new information on the deglacial and post-glacial evolution of the Arctic-Pacific connection through the Bering Strait based on analyses of geological and geophysical data from Herald Canyon, located north of the Bering Strait on the Chukchi Sea shelf region in the western Arctic Ocean. Our results suggest an initial opening at about 11 cal ka BP in the earliest Holocene, which is later than in several previous studies. Our key evidence is based on a well-dated core from Herald Canyon, in which a shift from a near-shore environment to a Pacific-influenced open marine setting at around 11 cal ka BP is observed. The shift corresponds to meltwater pulse 1b (MWP1b) and is interpreted to signify relatively rapid breaching of the Bering Strait and the submergence of the large Bering Land Bridge. Although the precise rates of sea level rise cannot be quantified, our new results suggest that the late deglacial sea level rise was rapid and occurred after the end of the Younger Dryas stadial.

The CAL: cognitive, apperceptive and representative aspects of fashion design - Side note to neuroaesthetic theory

NASA Astrophysics Data System (ADS)

Csanák, Edit

2017-10-01

This article deals with the creative and cognitive process of the creative work from the aspect of fashion design. It is examined through the Cognitive-Apperceptive-Limn process (The CAL), analysing the stages of design work referring to prominent literature, and discussing exciting theories, such the FLOW and the AHA effects are, and the neuro aesthetic theory. Setting them into a new context, the article offers a fresh approach of a designer, rather than a scientific statement based on pragmatic findings. Since theories on artistic performance and creativity can never be enough ‘empirical’, and the process can be never understood enough well…

Socio-demographic correlates of sexual behaviours: a cross sectional survey of adolescents in Imo State secondary schools.

PubMed

Nwoke, E A; Okafor, J O; Chukwuocha, U M; Nworuh, B O

2011-03-01

The study was designed to determine the socio-demographic correlates of sexual behaviours of the adolescents in Imo State secondary schools. Three objectives and three hypotheses were formulated to guide the study. A cross sectional survey design was used and sample size was 3360 (2.2%) adolescents. A structured, validated and reliable questionnaire (r = 0.79) and focus group discussion were used as the instruments for data collection. Data analysis was done using mean and ANOVA statistics. The result generally, showed that the average sexual behaviours of the adolescents were below the decision mean of 2.50 and as such the adolescents were said to be sexually inactive. In Imo State secondary schools, various family sizes did not significantly influence the sexual behaviours of the adolescents (F-cal. 2.39, F-tab. 3.00 & P > 0.05), family structure significantly influenced their sexual behaviours (F-cal. 17.78, F-tab. 3.00 & P < 0.05) and different financial strengths influenced the adolescents sexual behaviours significantly (F-cal. 22.88, F-tab. 2.37 & P < 0.05. Of great worry is that unrestricted/uncontrolled adolescents sexual behaviours may expose them to sexually transmitted infections/HIV/AIDS, unwanted pregnancies, illegal abortion and dropping out of school. Thus comprehensive sex education was recommended.

A High Resolution Spectroscopic Observation of CAL 83 with XMM-Newton/RGS

NASA Technical Reports Server (NTRS)

Paerels, Frits; Rasmussen, Andrew P.; Hartmann, H. W.; Heise, J.; Brinkman, A. C.; deVries, C. P.; denHerder, J.-W.

2000-01-01

We present the first high resolution photospheric X-ray spectrum of a Supersoft X-ray Source, the famous CAL 83 in the Large Magellanic Cloud. The spectrum was obtained with the Reflection Grating Spectrometer on XMM-Newton during the Calibration/Performance Verification phase of the observatory. The spectrum covers the range 20-40 A at an approximately constant resolution of 0.05 A, and shows very significant, intricate detail, that is very sensitive to the physical properties of the object. We present the results of an initial investigation of the spectrum, from which we draw the conclusion that the spectral structure is probably dominated by numerous absorption features due to transitions in the Gshells of the mid-2 elements and the M-shell of Fe, in addition to a few strong K-shell features due to CNO.

Woody vegetation, fuel and fire track the melting of the Scandinavian ice-sheet before 9500 cal yr BP

NASA Astrophysics Data System (ADS)

Carcaillet, Christopher; Hörnberg, Greger; Zackrisson, Olle

2012-11-01

New studies indicate the presence of early Holocene ice-free areas far north in Scandinavia. Post-glacial fire and vegetation were investigated based on sedimentary charcoal and pollen from two small lakes in northern Sweden. Accumulation of organic sediment started around 10,900 and 9200 cal yr BP, showing that both lake valleys were ice-free extremely early given their northerly location. Fire events started after 9600 cal yr BP and became less common around the '8.2-ka event'. Woody vegetation provided fuel that contributed to fires. The first vegetation in our pollen record consisted of Hippophae, Dryas, grasses and sedges. Subsequently broadleaved trees (Betula, Salix) increased in abundance and later Pinus, Alnus, ferns and Lycopodium characterized the vegetation. Pollen from Larix, Picea and Malus were also found. The change in vegetation composition was synchronous with the decrease in lake-water pH in the region, indicating ecosystem-scale processes; this occurred during a period of net global and regional warming. The changes in fire frequency and vegetation appear independent of regional trends in precipitation. The reconstructed fire history and vegetation support the scenario of early ice-free areas far north in Scandinavia during early Holocene warming, creating favorable conditions for woody plants and wildfires.

Source apportionment of methane and nitrous oxide in California's San Joaquin Valley at CalNex 2010 via positive matrix factorization

NASA Astrophysics Data System (ADS)

Guha, A.; Gentner, D. R.; Weber, R. J.; Provencal, R.; Goldstein, A. H.

2015-03-01

surprisingly given that organic and synthetic fertilizers are known to be a major source of N2O. The evaporative/fugitive source profile resembles a mix of petroleum operation and non-tailpipe evaporative gasoline sources, but was not responsible for any observed PMF resolved-CH4 enhancements. The vehicle emission source factor broadly matches VOC profiles of on-road exhaust sources and had no detected contribution to the N2O signals and negligible CH4 in the presence of a dominant dairy and livestock factor. The CalNex PMF study provides a measurement-based assessment of the state CH4 and N2O inventories for the southern San Joaquin valley. The state inventory attributes ~18% of the total N2O emissions to the transportation sector. Our PMF analysis directly contradicts the state inventory and demonstrates there were no discernible N2O emissions from the transportation sector.

Archaeomagnetic research in the United States midcontinent

NASA Astrophysics Data System (ADS)

Lengyel, Stacey Nicole

This dissertation combines archaeomagnetic and independent chronometric data from 240 archaeological features to develop a regional secular variation curve for the U.S. midcontinent. These data were obtained from features located between 31.5--40.5° N latitude and 82.5--93.5° W longitude that have been dated to between 60 and 10,700 cal BP. The archaeomagnetic samples were collected from 41 sites within this region over the past 35 years under the direction of four different researchers: Robert DuBois (University of Oklahoma), Daniel Wolfman (University of Arkansas and New Mexico State Museum), Wulf Gose (University of Texas at Austin), and myself. In this project, the data are initially smoothed through the moving windows method to form the first approximation of the curve. Outlier analyses and pairwise statistical comparisons are utilized to refine the smoothed curve, and the results are compared to other Holocene-aged secular variation records from North America. These analyses indicate that the final curve should be treated as three distinct segments with different precision and use recommendations. First, the 850--75 cal BP segment can be used to date archaeomagnetic sample from the project area with expected temporal precision of 100--200 years. Second, the 2528--850 cal BP segment can be used cautiously to date archaeomagnetic samples with an expected temporal precision of 200--300 years. Third, the 9755--4650 cal BP segment should be used for contextual dating purposes only, in that an undated sample can be put into a regional context through comparison with the segment's constituent samples. Finally, three archaeological problems are addressed through the archaeomagnetic data. First, archaeomagnetic data are used to resolve the temporal conflict between an eastern Tennessee structure's morphology and a much earlier radiocarbon date obtained for the structure. Then, archaeomagnetic data are used to address a number of internal chronology questions

Identification and synchronization of the common cosmic-ray signal in the IntCal13 14C calibration and the Greenland ice-core 10Be records

NASA Astrophysics Data System (ADS)

Muscheler, Raimund; Adolphi, Florian; Bronk Ramsey, Christopher; Rasmussen, Sune; Hughen, Konrad; Cooper, Alan; Turney, Chris

2017-04-01

The production rates of cosmogenic radionuclides (such as 10Be and 14C) are modulated by the solar and geomagnetic shielding of galactic cosmic rays. In addition, 14C and 10Be are influenced by the carbon cycle and the atmospheric transport and deposition, respectively. Isolating and identifying the common production signal allows us to synchronize ice core 10Be and tree ring 14C records during the Holocene (Adolphi and Muscheler, 2016), thereby connecting ice core climate records with 14C-dated records. Extending this comparison further back in time is challenging due to deteriorating quality of the 14C calibration record, IntCal13, (Reimer et al., 2013) and possible unidentified climate influences on the ice-core 10Be records. Nevertheless, by focusing on the most prominent production-rate features this comparison can be extended far back into the last glacial where, for example, the linkage of tree-ring based Kauri 14C data and the Greenland ice-core time scale (GICC05) suggested unresolved data and/or time scale differences around the period of the Laschamp geomagnetic field minimum at about 42000 yrs BP (Muscheler et al., 2014). Here we show that the data underlying the IntCal13 14C record and the ice-core 10Be records exhibit common variability that allows us to tentatively link the ice core GICC05 time scale to the radiocarbon time scale for almost the complete radiocarbon dating range. The observed time scale differences could be related to uncertainties in both the U/Th-based dating of the IntCal13 calibration data set and the GICC05 time scale, and we show that the two can be reconciled within the uncertainties of the ice-core layer counting. This direct comparison between IntCal13 and 10Be also suggests that the 14C differences shown in (Muscheler et al., 2014) around the Laschamp geomagnetic field minimum can be reduced by moderate adjustments to the GICC05 time scale. References: Adolphi, F., and Muscheler, R., 2016, Synchronizing the Greenland ice

Military Intelligence Professional Bulletin (MIPB). Volume 37, Number 2, April-June 2011

DTIC Science & Technology

2011-04-01

holds an MA in Anthropology from California State University, Fullerton. 14 Military Intelligence “Harder to Do Than I Thought” Developing...intelligence is anthropological intelligence, no matter what forms it may take. Intelligence is an- thropological because it defi nes what it means...enlightenment. What we anthropologically call culture underlies and contextualizes all of our intelligence. We are culturally dependent creatures of

Are Avellino (4365 cal BP) and Pompeii twin plinian eruptions? Pre-eruptive constraints and degassing history

NASA Astrophysics Data System (ADS)

Boudon, Georges; Balcone-Boissard, Hélène; Villemant, Benoît.; Ucciani, Guillaume; Cioni, Raffaello

2010-05-01

Somma-Vesuvius activity started 35 ky ago and is characterized by numerous eruptions of variable composition and eruptive style, sometimes interrupted by long periods of unrest. The main explosive eruptions are represented by four plinian eruptions: Pomici di Base eruption (22 cal ky), Mercato (~8900 cal BP), Avellino (4365 cal BP) and Pompeii (79 AD). The 79 AD eruption embodies the most famous eruption since it's responsible of the destruction of Pompeii and Herculanum and it's the first described eruption. The Avellino eruption represents the last plinian event that preceded the Pompeii eruption. The eruptive sequence is similar to the 79 AD plinian eruption, with an opening phase preceding a main plinian fallout activity which ended by a phreatomagmatic phase. The fallout deposit displays a sharp colour contrast from white to grey pumice, corresponding to a magma composition evolution. We focus our study on the main fallout deposit that we sampled in detail in the Traianello quarry, 9 km North-North East of the crater, to investigate the degassing processes during the eruption, using volatile content and textural observations. Density and vesicularity measurements were obtained on a minimum of 100 pumice clasts sampled in 10 stratigraphic levels in the fallout deposit. On the basis of the density distribution, bulk geochemical data, point analytical measurements on glasses (melt inclusions and residual glass) and textural observations were obtained simultaneously on a minimum of 5 pumice clasts per eruptive unit. The glass composition, in particular the Na/K ratio, evolves from Na-rich phonolite for white pumices to a more K-rich phonolite for grey pumices. The pre-eruptive conditions are constrained by systematic Cl measurements in melt inclusions and matrix glass of pumice clasts. The entire magma was saturated relative to sub-critical fluids (a Cl-rich H2O vapour phase and a brine), with a Cl melt content buffered at ~6000 ppm, and a mean pre-eruptive H2O

Coatings of black carbon in Tijuana, Mexico, during the CalMex Campaign

NASA Astrophysics Data System (ADS)

Takahama, S.; Russell, L. M.; Duran, R.; Subramanian, R.; Kok, G.

2010-12-01

Black carbon number and mass concentrations were measured by a single-particle soot photometer (SP2; by Droplet Measurement Technologies) in Tijuana, Mexico between May 15, 2010, and June 30, 2010, for the CalMex campaign. The measurement site, Parque Morelos, is a recreational area located in the Southeast region of Tijuana. The SP2 was equipped with 8-channels of signal detection that spans a wider range of sensitivity for incandescing and scattering measurements than traditional configurations. The campaign-average number concentration of incandescing particles was 280 #/cc, peaking during traffic activity in the mornings. Incandescing particles made up 50% of all particles (incandescing and purely scattering) detected by the SP2. The mode of the number size distribution estimated for black carbon, according to estimated mass-equivalent diameters, was approximately 100 nm or smaller. Temporal variations in estimated coating thicknesses for these black carbon particles are discussed together with co-located measurements of organic aerosol and inorganic salts.

Sea-based Infrared Radiance Measurements of Ocean and Atmosphere from the ACAPEX/CalWater2 Campaign

NASA Astrophysics Data System (ADS)

Gero, P. J.; Knuteson, R.; Hackel, D.; Phillips, C.; Westphall, M.

2015-12-01

The ARM Cloud Aerosol Precipitation Experiment (ACAPEX) / CalWater2 was a joint DOE/NOAA field campaign in early 2015 to study atmospheric rivers in the Pacific Ocean and their impacts on the western United States. The campaign goals were to improve understanding and modeling of large-scale dynamics and cloud and precipitation processes associated with atmospheric rivers and aerosol-cloud interactions that influence precipitation variability and extremes in the western United States. Coordinated measurements were made from ground-, aircraft- and sea-based platforms. The second ARM mobile facility (AMF-2) was deployed on board the NOAA Ship Ronald H. Brown for this campaign, which included a new Marine Atmospheric Emitted Radiance Interferometer (M-AERI) to measure the atmospheric downwelling and reflected infrared radiance spectrum at the Earth's surface with high absolute accuracy. The M-AERI measures spectral infrared radiance between 520-3020 cm-1 (3.3-19 μm) at a resolution of 0.5 cm-1. The M-AERI can selectively view the atmospheric scene at zenith, and ocean/atmospheric scenes over a range of ±45° from the horizon. The AERI uses two high-emissivity blackbodies for radiometric calibration, which in conjunction with the instrument design and a suite of rigorous laboratory diagnostics, ensures the radiometric accuracy to be better than 1% (3σ) of the ambient radiance. The M-AERI radiance spectra can be used to retrieve profiles of temperature and water vapor in the troposphere, as well as measurements of trace gases, cloud properties, surface emissivity and ocean skin temperature. We present preliminary results on measurements of ocean skin temperature, ocean emissivity properties as a function of view angle and wind speed, as well as comparisons with radiosondes and satellite observations.

The beginning of metallurgy in the southern Levant: a late 6th millennium CalBC copper awl from Tel Tsaf, Israel.

PubMed

Garfinkel, Yosef; Klimscha, Florian; Shalev, Sariel; Rosenberg, Danny

2014-01-01

The beginning of metallurgy in the ancient Near East attracts much attention. The southern Levant, with the rich assemblage of copper artifacts from the Nahal Mishmar cave and the unique gold rings of the Nahal Qanah cave, is regarded as a main center of early metallurgy during the second half of the 5th millennium CalBC. However, a recently discovered copper awl from a Middle Chalcolithic burial at Tel Tsaf, Jordan Valley, Israel, suggests that cast metal technology was introduced to the region as early as the late 6th millennium CalBC. This paper examines the chemical composition of this item and reviews its context. The results indicate that it was exported from a distant source, probably in the Caucasus, and that the location where it was found is indicative of the social status of the buried individual. This rare finding indicates that metallurgy was first diffused [corrected] to the southern Levant through exchange networks and only centuries later involved local productionThis copper awl, the earliest metal artifact found in the southern Levant, indicates that the elaborate Late Chalcolithic metallurgy developed from a more ancient tradition.

The Beginning of Metallurgy in the Southern Levant: A Late 6th Millennium CalBC Copper Awl from Tel Tsaf, Israel

PubMed Central

Garfinkel, Yosef; Klimscha, Florian; Shalev, Sariel; Rosenberg, Danny

2014-01-01

The beginning of metallurgy in the ancient Near East attracts much attention. The southern Levant, with the rich assemblage of copper artifacts from the Nahal Mishmar cave and the unique gold rings of the Nahal Qanah cave, is regarded as a main center of early metallurgy during the second half of the 5th millennium CalBC. However, a recently discovered copper awl from a Middle Chalcolithic burial at Tel Tsaf, Jordan Valley, Israel, suggests that cast metal technology was introduced to the region as early as the late 6th millennium CalBC. This paper examines the chemical composition of this item and reviews its context. The results indicate that it was exported from a distant source, probably in the Caucasus, and that the location where it was found is indicative of the social status of the buried individual. This rare finding indicates that metallurgy was first defused to the southern Levant through exchange networks and only centuries later involved local production. This copper awl, the earliest metal artifact found in the southern Levant, indicates that the elaborate Late Chalcolithic metallurgy developed from a more ancient tradition. PMID:24671185

DSMC (Defense Systems Management College) CALS (Computer-Aided Acquisition and Logistics Support) Briefing: Program Manager Course.

DTIC Science & Technology

1988-11-01

library . o Air Force Tech Order Management System - Final Report, library o DLA CALS 1988 Implementation Plan, library . Where to go for Additional...0. ~l l LU; 0. 0 0 2. o 3 0 I) 0 U no V) 4- C 4. U) 00 u c.C0 Cco C Cl) cc m~0-CU . d" CD 0 m mooc Er.C 0 .0> s -w 2 c IM CO (aC wi E 0 r. X 0-0 a 0...as well as wider application. The Air Force AFTOMS Automation Plan, a copy of which is in the library , has excellent discussions of the expected

A comparison of the Greenland ice-core and IntCal timescales through the Laschamp geomagnetic excursion, utilising new 14C data from Tenaghi Philippon, Greece

NASA Astrophysics Data System (ADS)

Staff, Richard; Hardiman, Mark; Bronk Ramsey, Christopher; Hare, Vincent; Koutsodendris, Andreas; Pross, Jörg

2017-04-01

Cosmogenic radionuclides, such as 10Be and 14C, share a common production signal, with their formation in the Earth's upper atmosphere modulated by changes to the geomagnetic field, as well as variations in the intensity of the solar wind. Here, we present 54 14C measurements from a terrestrial fen peat core extracted from the site of Tenaghi Philippon, NE Greece, contiguously spanning the time period between 48,000 and 39,000 cal. BP. Utilising the most pronounced cosmogenic production peak of the last 100,000 years - that associated with the Laschamp geomagnetic excursion circa 41,000 years ago - we exploit this common production signal, comparing Greenland 10Be with our Tenaghi Philippon 14C record, thereby providing a means to assess the concordance between the radiocarbon (IntCal) and Greenland ice-core (GICC05) timescales themselves for this, the oldest portion of the radiocarbon technique.

Organic aerosol composition and sources in Pasadena, California, during the 2010 CalNex campaign

NASA Astrophysics Data System (ADS)

Hayes, P. L.; Ortega, A. M.; Cubison, M. J.; Froyd, K. D.; Zhao, Y.; Cliff, S. S.; Hu, W. W.; Toohey, D. W.; Flynn, J. H.; Lefer, B. L.; Grossberg, N.; Alvarez, S.; Rappenglück, B.; Taylor, J. W.; Allan, J. D.; Holloway, J. S.; Gilman, J. B.; Kuster, W. C.; de Gouw, J. A.; Massoli, P.; Zhang, X.; Liu, J.; Weber, R. J.; Corrigan, A. L.; Russell, L. M.; Isaacman, G.; Worton, D. R.; Kreisberg, N. M.; Goldstein, A. H.; Thalman, R.; Waxman, E. M.; Volkamer, R.; Lin, Y. H.; Surratt, J. D.; Kleindienst, T. E.; Offenberg, J. H.; Dusanter, S.; Griffith, S.; Stevens, P. S.; Brioude, J.; Angevine, W. M.; Jimenez, J. L.

2013-08-01

Organic aerosols (OA) in Pasadena are characterized using multiple measurements from the California Research at the Nexus of Air Quality and Climate Change (CalNex) campaign. Five OA components are identified using positive matrix factorization including hydrocarbon-like OA (HOA) and two types of oxygenated OA (OOA). The Pasadena OA elemental composition when plotted as H : C versus O : C follows a line less steep than that observed for Riverside, CA. The OOA components from both locations follow a common line, however, indicating similar secondary organic aerosol (SOA) oxidation chemistry at the two sites such as fragmentation reactions leading to acid formation. In addition to the similar evolution of elemental composition, the dependence of SOA concentration on photochemical age displays quantitatively the same trends across several North American urban sites. First, the OA/ΔCO values for Pasadena increase with photochemical age exhibiting a slope identical to or slightly higher than those for Mexico City and the northeastern United States. Second, the ratios of OOA to odd-oxygen (a photochemical oxidation marker) for Pasadena, Mexico City, and Riverside are similar, suggesting a proportional relationship between SOA and odd-oxygen formation rates. Weekly cycles of the OA components are examined as well. HOA exhibits lower concentrations on Sundays versus weekdays, and the decrease in HOA matches that predicted for primary vehicle emissions using fuel sales data, traffic counts, and vehicle emission ratios. OOA does not display a weekly cycle—after accounting for differences in photochemical aging —which suggests the dominance of gasoline emissions in SOA formation under the assumption that most urban SOA precursors are from motor vehicles.

The diffusion of maize to the southwestern United States and its impact

PubMed Central

Merrill, William L.; Hard, Robert J.; Mabry, Jonathan B.; Fritz, Gayle J.; Adams, Karen R.; Roney, John R.; MacWilliams, A. C.

2009-01-01

Our understanding of the initial period of agriculture in the southwestern United States has been transformed by recent discoveries that establish the presence of maize there by 2100 cal. B.C. (calibrated calendrical years before the Christian era) and document the processes by which it was integrated into local foraging economies. Here we review archaeological, paleoecological, linguistic, and genetic data to evaluate the hypothesis that Proto-Uto-Aztecan (PUA) farmers migrating from a homeland in Mesoamerica introduced maize agriculture to the region. We conclude that this hypothesis is untenable and that the available data indicate instead a Great Basin homeland for the PUA, the breakup of this speech community into northern and southern divisions ≈6900 cal. B.C. and the dispersal of maize agriculture from Mesoamerica to the US Southwest via group-to-group diffusion across a Southern Uto-Aztecan linguistic continuum. PMID:19995985

Effect of sexed-semen use on Holstein conception rate, calf sex, dystocia, and stillbirth in the United States

USDA-ARS?s Scientific Manuscript database

Most artificial-insemination organizations in the United States now market sex-sorted semen. For 10.8 million US Holstein breedings with conventional semen since January 2006 and 122,705 sexed-semen breedings, data were available from all breedings for conception rate, 12 and 9% of breedings for cal...

Mass concentration, composition and sources of fine and coarse particulate matter in Tijuana, Mexico, during Cal-Mex campaign

NASA Astrophysics Data System (ADS)

Minguillón, María Cruz; Campos, Arturo Alberto; Cárdenas, Beatriz; Blanco, Salvador; Molina, Luisa T.; Querol, Xavier

2014-05-01

This work was carried out in the framework of the Cal-Mex project, which focuses on investigating the atmosphere along Mexico-California border region. Sampling was carried out at two sites located in Tijuana urban area: Parque Morelos and Metales y Derivados. PM2.5 and PM10 24 h samples were collected every three days from 17th May 2010 to 27th June 2010, and were used for gravimetric and chemical analyses (major and minor elements, inorganic ions, organic and elemental carbon) of PM. A subsequent Positive Matrix Factorization (PMF) analysis was performed. PM2.5 and PM10 average concentrations during Cal-Mex were relatively lower compared to usual annual averages. Trace elements concentrations recorded in the present study were lower than those recorded in Mexico City in 2006, with the exception of Pb at Metales y Derivados, attributed to the influence of a specific industrial source, which also includes As, Cd and Tl. Apart from this industrial source, both urban sites were found to be affected by similar sources with respect to bulk PM. Fine PM (PM2.5) was mainly apportioned by fueloil and biomass combustion and secondary aerosols, and road traffic. Coarse PM (PM2.5-10) was mainly apportioned by a mineral source (sum of road dust resuspension, construction emissions and natural soil) and fresh and aged sea salt. The road traffic was responsible for more than 60% of the fine elemental carbon and almost 40% of the fine organic matter.

The Case for Nation-building: Why and How to Fix Failed States

DTIC Science & Technology

2011-12-01

Asia), pandemic disease (AIDS), and ecologi - cal disaster—to say nothing of the occasional global terrorist organization. Time and time again...borders. And piracy along the east coast of Africa has increased over the last two decades since Somalia’s collapse into anarchy . These threats...ignore the problems, allow anarchy to consume failed states, and pay ever higher costs to isolate themselves and repair any damage after the fact. But

Modeling the formation and aging of secondary organic aerosols during CalNex 2010

NASA Astrophysics Data System (ADS)

Hayes, P. L.; Ortega, A. M.; Ahmadov, R.; McKeen, S. A.; Washenfelder, R. A.; Alvarez, S.; Rappenglueck, B.; Holloway, J. S.; Gilman, J. B.; Kuster, W. C.; De Gouw, J. A.; Zotter, P.; Prevot, A. S.; Kleindienst, T. E.; Offenberg, J. H.; Jimenez, J. L.

2012-12-01

Several traditional and recently proposed models are applied to predict the concentrations and properties of secondary organic aerosols (SOA) and organic gases at the Pasadena ground site during the CalNex campaign. The models are constrained with and compared against results from available observations. The CalNex campaign and specifically the Pasadena ground site featured a large and sophisticated suite of aerosol and gas phase instrumentation, and thus, it provides a unique opportunity to test SOA models under conditions of strong urban emissions at a range of low photochemical ages. The oxidation of volatile organic compounds (VOCs) using an updated traditional model cannot explain the observed ambient SOA, and under-predicts the measurements by a factor of ~40. Similarly, after accounting for the multi-generation oxidation of VOCs using a volatility basis set (VBS) approach as described by Tsimpidi et al. (2010), SOA is still under-predicted by a factor of ~8. For SOA formed from VOCs (V-SOA) the dominant precursors are aromatics (xylenes, toluene, and trimethylbenzenes). The model SOA formed from the oxidation of primary semivolatile and intermediate volatility organic compounds (P-S/IVOCs, producing SI-SOA) is also predicted using the parameterizations of Robinson et al. (2007) and Grieshop et al. (2009), and the properties of V-SOA + SI-SOA are compared against the measured O:C and volatility. We also compare the results of the different models against fossil/non-fossil carbon measurements as well as tracers of different SOA precursors. Potential Aerosol Mass (PAM) measurements of the SOA forming potential of the Pasadena air masses are also compared against that predicted by the models. The PAM analysis allows for model/measurement comparisons of SOA properties over a range of photochemical ages spanning almost two weeks. Using the V-SOA model, at low photochemical ages (< 1 day) the modeled PAM V-SOA is less than the measured PAM SOA, similar to the

Racial/Ethnic Disparities in Cumulative Environmental Health Impacts in California: Evidence From a Statewide Environmental Justice Screening Tool (CalEnviroScreen 1.1)

PubMed Central

Faust, John; August, Laura Meehan; Cendak, Rose; Wieland, Walker; Alexeeff, George

2015-01-01

Objectives. We used an environmental justice screening tool (CalEnviroScreen 1.1) to compare the distribution of environmental hazards and vulnerable populations across California communities. Methods. CalEnviroScreen 1.1 combines 17 indicators created from 2004 to 2013 publicly available data into a relative cumulative impact score. We compared cumulative impact scores across California zip codes on the basis of their location, urban or rural character, and racial/ethnic makeup. We used a concentration index to evaluate which indicators were most unequally distributed with respect to race/ethnicity and poverty. Results. The unadjusted odds of living in one of the 10% most affected zip codes were 6.2, 5.8, 1.9, 1.8, and 1.6 times greater for Hispanics, African Americans, Native Americans, Asian/Pacific Islanders, and other or multiracial individuals, respectively, than for non-Hispanic Whites. Environmental hazards were more regressively distributed with respect to race/ethnicity than poverty, with pesticide use and toxic chemical releases being the most unequal. Conclusions. Environmental health hazards disproportionately burden communities of color in California. Efforts to reduce disparities in pollution burden can use simple screening tools to prioritize areas for action. PMID:26378826

The glyoxal budget and its contribution to organic aerosol for Los Angeles, California, during CalNex 2010

NASA Astrophysics Data System (ADS)

Washenfelder, R. A.; Young, C. J.; Brown, S. S.; Angevine, W. M.; Atlas, E. L.; Blake, D. R.; Bon, D. M.; Cubison, M. J.; de Gouw, J. A.; Dusanter, S.; Flynn, J.; Gilman, J. B.; Graus, M.; Griffith, S.; Grossberg, N.; Hayes, P. L.; Jimenez, J. L.; Kuster, W. C.; Lefer, B. L.; Pollack, I. B.; Ryerson, T. B.; Stark, H.; Stevens, P. S.; Trainer, M. K.

2011-11-01

Recent laboratory and field studies have indicated that glyoxal is a potentially large contributor to secondary organic aerosol mass. We present in situ glyoxal measurements acquired with a recently developed, high sensitivity spectroscopic instrument during the CalNex 2010 field campaign in Pasadena, California. We use three methods to quantify the production and loss of glyoxal in Los Angeles and its contribution to organic aerosol. First, we calculate the difference between steady state sources and sinks of glyoxal at the Pasadena site, assuming that the remainder is available for aerosol uptake. Second, we use the Master Chemical Mechanism to construct a two-dimensional model for gas-phase glyoxal chemistry in Los Angeles, assuming that the difference between the modeled and measured glyoxal concentration is available for aerosol uptake. Third, we examine the nighttime loss of glyoxal in the absence of its photochemical sources and sinks. Using these methods we constrain the glyoxal loss to aerosol to be 0-5 × 10-5 s-1 during clear days and (1 ± 0.3) × 10-5 s-1 at night. Between 07:00-15:00 local time, the diurnally averaged secondary organic aerosol mass increases from 3.2 μg m-3 to a maximum of 8.8 μg m-3. The constraints on the glyoxal budget from this analysis indicate that it contributes 0-0.2 μg m-3 or 0-4% of the secondary organic aerosol mass.

The Glyoxal Budget and Its Contribution to Organic Aerosol for Los Angeles, California During CalNex 2010

NASA Astrophysics Data System (ADS)

Washenfelder, R. A.; Young, C. J.; Brown, S. S.; Angevine, W. M.; Atlas, E. L.; Blake, D. R.; Bon, D.; Cubison, M.; De Gouw, J. A.; Dusanter, S.; Flynn, J. H.; Gilman, J. B.; Graus, M.; Griffith, S. M.; Grossberg, N.; Hayes, P. L.; Jimenez, J. L.; Kuster, W. C.; Lefer, B. L.; Pollack, I. B.; Ryerson, T. B.; Stark, H.; Stevens, P. S.; Trainer, M.

2011-12-01

Recent laboratory and field studies have indicated that glyoxal is a potentially large contributor to secondary organic aerosol mass. We present in situ glyoxal measurements acquired with a recently developed, high sensitivity spectroscopic instrument during the CalNex 2010 field campaign in Pasadena, California. We use three methods to quantify the production and loss of glyoxal in Los Angeles and its contribution to organic aerosol. First, we calculate the difference between steady-state sources and sinks of glyoxal at the Pasadena site, assuming that the remainder is available for aerosol uptake. Second, we use the Master Chemical Mechanism to construct a two-dimensional model for gas-phase glyoxal chemistry in Los Angeles, assuming that the difference between the modeled and measured glyoxal concentration is available for aerosol uptake. Third, we examine the nighttime loss of glyoxal in the absence of its photochemical sources and sinks. Using these methods we constrain the glyoxal loss to aerosol to be 0 - 5 × 10-5 s-1 during clear days and (1 ± 0.3) × 10-5 s-1 at night. Between 07:00 - 15:00 local time, the diurnally-averaged secondary organic aerosol mass increases from 4.4 μg m-3 to a maximum of 9.3 μg m-3. The constraints on the glyoxal budget from this analysis indicate that it contributes 0 - 0.2 μg m-3 or 0 - 4% of the secondary organic aerosol mass.

Parameters. US Army War College Quarterly. Volume 25. Number 1. Spring 1995,

DTIC Science & Technology

1995-01-01

major reason the fratricide rate remains so high is that imperfect human skills and judgment needed to employ weapon systems quickly degrade under...and rehearsals before the Desert Storm ground campaign, the residual rate of fratricide remained unacceptably high. Nor are the high rates at our combat...California State University, Fullerton. He is the editor and an author of The Search For Strategy: Politics and Strategic Vision. Spring 1995 31 Haiti, Peru

Sentinel-2: presentation of the CAL/VAL commissioning phase

NASA Astrophysics Data System (ADS)

Trémas, Thierry L.; Déchoz, Cécile; Lacherade, Sophie; Nosavan, Julien; Petrucci, Beatrice

2015-10-01

In partnership with the European Commission and in the frame of the Copernicus program, the European Space Agency (ESA) has developed the Sentinel-2 optical imaging mission devoted to the operational monitoring of land and coastal areas. The Sentinel-2 mission is based on a satellites constellation deployed in polar sun-synchronous orbits. Sentinel-2 will offer a unique combination of global coverage with a wide field of view (290km), a high revisit (5 days with two satellites), a high resolution (10m, 20m and 60m) and multi-spectral imagery (13 spectral bands in visible and shortwave infra-red domains). The first sentinel 2A has been launched on June 22nd, 2015, from Kourou, French Guyana. In this context, the Centre National d'Etudes Spatiales (CNES) supports ESA to insure the cal/val commissioning phase, for Image Quality aspects. This paper provides first, an overview of the Sentinel-2 system after the launch. Then the articles focuses on the means implemented and activated in CNES to perform the In Orbit Commissioning, the availability and performances of the different devices involved in the ground segment : the GPP in charge of producing the level 1 files, the "radiometric unit" that processes sensitivity parameters, the "geometric unit" in charge of fitting the images on a reference map, MACCS that will produce Level 2A files (computing reflectances at the Bottom of Atmosphere) and the TEC-S2 that will coordinate all the previous software and drive a database in which will be gather the incoming Level 0 files and the processed Level 1 files.

From surprise to cognition: Some effects of the structure of C.A.L. simulation programs on the cognitive and scientific activities of young adults

NASA Astrophysics Data System (ADS)

Dicker, R. J.

The main objective of this thesis is to describe the effect on cognition of the structure of CAL simulation programs used, in science teaching. Four programs simulating a pond ecosystem were written so as to present a simulation model and to assist in cognition in different ways. Various clinically detailed methods of describing learning were developed and tried including concept maps which were found to be sammative rather than formative descriptions of learning, and to be ambiguous) and hierarchical structures (which were found to be difficult to produce). Fran these concept maps and hierarchical structures I developed my Interaction Model of Learning which can be used to describe the chronological events concerned with cognition. Using the Interaction Model, the nature of cognition and the effect that CAL program structure has on this process is described. Various scenarios are presented as a means of showing the possible effects of program structure on learning. Four forms of concept learning activity and their relationship to learning valid and alternative conceptions are described. The findings from the study are particularly related to the work of Driver (1983), Marton (1976) and Entwistle (1981).

United States Air Force Research Initiation Program. 1984 Research Reports. Volume 1.

DTIC Science & Technology

1986-05-01

storage , several 8" floppy disk drives were substituteu; to gain the equivalent speed, an 8088 microprocessor faster than the Intel version and a 2-wegabyte... RAil .. cnory and ram-drive software were substituted. 2. Not included above is one item which was listed in the RISE proposal budget (the Z-204...FUSOIONCAL/JM. 280 REM C4IHEAT CAPACITYiCAL/GM-K. 2,90 C=0.46 00’ REM E1=ACTIVATION ENERGYiCAL /MOL. 3 2’ REM R-GAS CONSTANTiCAL/MOL-K. F!’ = 1. 9 B37 .* 3

Source apportionment of methane and nitrous oxide in California's San Joaquin Valley at CalNex 2010 via positive matrix factorization

NASA Astrophysics Data System (ADS)

Guha, A.; Gentner, D. R.; Weber, R. J.; Provencal, R.; Goldstein, A. H.

2015-10-01

conducted bootstrapping analysis. This is most likely due to an asynchronous pattern of soil-mediated N2O emissions from fertilizer usage and collocated biogenic emissions from crops from the surrounding agricultural operations that is difficult to apportion statistically when using PMF. The evaporative/fugitive source profile, which resembled a mix of petroleum operation and non-tailpipe evaporative gasoline sources, did not include a PMF resolved-CH4 contribution that was significant (< 2 %) compared to the uncertainty in the livestock-associated CH4 emissions. The uncertainty of the CH4 estimates in this source factor, derived from the bootstrapping analysis, is consistent with the ~ 3 % contribution of fugitive oil and gas emissions to the statewide CH4 inventory. The vehicle emission source factor broadly matched VOC profiles of on-road exhaust sources. This source factor had no statistically significant detected contribution to the N2O signals (confidence interval of 3 % of livestock N2O enhancements) and negligible CH4 (confidence interval of 4 % of livestock CH4 enhancements) in the presence of a dominant dairy and livestock factor. The CalNex PMF study provides a measurement-based assessment of the state CH4 and N2O inventories for the southern San Joaquin Valley (SJV). The state inventory attributes ~ 18 % of total N2O emissions to the transportation sector. Our PMF analysis directly contradicts the state inventory and demonstrates there were no discernible N2O emissions from the transportation sector in the southern SJV region.

Risk of preterm birth by subtype among Medi-Cal participants with mental illness.

PubMed

Baer, Rebecca J; Chambers, Christina D; Bandoli, Gretchen; Jelliffe-Pawlowski, Laura L

2016-10-01

Previous studies have demonstrated an association between mental illness and preterm birth (before 37 weeks). However, these investigations have not simultaneously considered gestation of preterm birth, the indication (eg, spontaneous or medically indicated), and specific mental illness classifications. The objective of the study was to examine the likelihood of preterm birth across gestational lengths and indications among Medi-Cal (California's Medicaid program) participants with a diagnostic code for mental illness. Mental illnesses were studied by specific illness classification. The study population was drawn from singleton live births in California from 2007 through 2011 in the birth cohort file maintained by the California Office of Statewide Health Planning and Development, which includes birth certificate and hospital discharge records. The sample was restricted to women with Medi-Cal coverage for prenatal care. Women with mental illness were identified using International Classification of Diseases, ninth revision, codes from their hospital discharge record. Women without a mental illness International Classification of Diseases, ninth revision, code were randomly selected at a 4:1 ratio. Adjusting for maternal characteristics and obstetric complications, relative risks and 95% confidence intervals were calculated for preterm birth comparing women with a mental illness diagnostic code with women without such a code. We identified 6198 women with a mental illness diagnostic code and selected 24,792 women with no such code. The risk of preterm birth in women with a mental illness were 1.2 times higher than women without a mental illness (adjusted relative risk, 1.2, 95% confidence interval, 1.1-1.3). Among the specific mental illnesses, schizophrenia, major depression, and personality disorders had the strongest associations with preterm birth (adjusted relative risks, 2.0, 2.0 and 3.3, respectively). Women receiving prenatal care through California's low

Circum-Mediterranean fire activity and climate changes during the mid Holocene environmental transition (8500-2500 cal yr BP)

NASA Astrophysics Data System (ADS)

Vannière, Boris; Power, Mitch J.; Roberts, Neil; Tinner, Willy; Carrión, José; Magny, Michel; Bartlein, Patrick

2010-05-01

In this contribution I will present a synthesis of mid- to late-Holocene fire activity from the Mediterranean basin and explore the linkages among fire, climate variability and seasonality, and people through several climatic and ecological transitions. Regional fire histories were created from 36 radiocarbon-dated sedimentary charcoal records, available from the Global Charcoal Database. During the mid-Holocene "Thermal Maximum", charcoal records from the northern Mediterranean suggest the region was more fire prone while records from the southern Mediterranean indicate a decrease in fire activity associated with wetter-than-present summers. A North-South partition at 40-43°N is apparent in the central and western Mediterranean. In the context of orbitally-induced summer insolation decrease, South Mediterranean wet conditions could be linked to the Afro-Asian summer monsoon which weakened after ca. 8000-6000 cal yr BP. Relatively abrupt changes in fire regime observed at ca. 5500-5000 cal yr BP may be associated to a threshold in this weakening influence of the orbitally-driven Afro-Asian monsoon strength. Charcoal records of past fire activity appear sensitive to both orbitally-forced climate changes and shorter lived excursions which may be related to cold events apparent in the North Atlantic record of ice-rafted debris. These results contradict former notions of gradual aridification of the entire region due to climatic forcing and/or human activities. In contrast, they suggest: 1) Teleconnections between the Mediterranean area and other climatic regions, in particular the North Atlantic and the low-latitude monsoon areas, influenced past fire regimes; 2) Gradual forcing, such as changes in orbital parameters, may have triggered more abrupt shifts in fire regime, either directly or indirectly through these teleconnections.

Pre-STS-3 press conference held at the JSC public affairs facility

NASA Image and Video Library

1982-01-25

S82-25905 (21 Jan. 1982) --- Astronaut C. Gordon Fullerton uses an electronic pointer to localize an area on a projected visual of the OSS payload package to be carried in the cargo bay of the Columbia on STS-3. Fullerton is pilot for the flight and Jack R. Lousma, center, is mission commander. The two were holding one of a series of pre-STS-3 press briefings. They were introduced by Dr. John Lawrence, far right, a public information specialist for JSC?s Office of Public Affairs. Photo credit: NASA

Ground States of Random Spanning Trees on a D-Wave 2X

NASA Astrophysics Data System (ADS)

Hall, J. S.; Hobl, L.; Novotny, M. A.; Michielsen, Kristel

The performances of two D-Wave 2 machines (476 and 496 qubits) and of a 1097-qubit D-Wave 2X were investigated. Each chip has a Chimera interaction graph calG . Problem input consists of values for the fields hj and for the two-qubit interactions Ji , j of an Ising spin-glass problem formulated on calG . Output is returned in terms of a spin configuration {sj } , with sj = +/- 1 . We generated random spanning trees (RSTs) uniformly distributed over all spanning trees of calG . On the 476-qubit D-Wave 2, RSTs were generated on the full chip with Ji , j = - 1 and hj = 0 and solved one thousand times. The distribution of solution energies and the average magnetization of each qubit were determined. On both the 476- and 1097-qubit machines, four identical spanning trees were generated on each quadrant of the chip. The statistical independence of these regions was investigated. In another study, on the D-Wave 2X, one hundred RSTs with random Ji , j ∈ { - 1 , 1 } and hj = 0 were generated on the full chip. Each RST problem was solved one hundred times and the number of times the ground state energy was found was recorded. This procedure was repeated for square subgraphs, with dimensions ranging from 7 ×7 to 11 ×11. Supported in part by NSF Grants DGE-0947419 and DMR-1206233. D-Wave time provided by D-Wave Systems and by the USRA Quantum Artificial Intelligence Laboratory Research Opportunity.

Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment.

PubMed

Kraljević Pavelić, Sandra; Marjanović, Marko; Poznić, Miroslav; Kralj, Marijeta

2009-12-01

p53 gene plays a crucial role in the response to therapy. Since it is inactivated in the majority of human cancers, it is strongly believed that the p53 mutations confer resistance to therapeutics. In this paper we analyzed the influence of two mechanistically diverse antitumor agents--cisplatin and methotrexate on the proliferation and cell cycle of two head and neck squamous cancer cell lines HEp-2 (wild type p53 gene, but HPV 18/E6-inactivated protein) and CAL 27 (mutated p53 gene), along with the influence of adenovirally mediated p53 overexpression in modulation of cisplatin and methoterexate effects, whereby subtoxic vector/compound concentrations were employed. p53 gene was introduced into tumor cells using adenoviral vector (AdCMV-p53). The cell cycle perturbations were measured by two parameter flow cytometry. The expression of p53, p21(WAF1/CIP1) and cyclin B1 proteins was examined using immunocytochemistry and western blot methods. In CAL 27 cells overexpression of p53 completely abrogated high S phase content observed in methotrexate-treated cells into a G1 and slight G2 arrest, while it sustained G2 arrest of the cells treated with cisplatin, along with the reduction of DNA synthesis and cyclin B1 expression. On the other hand, in HEp-2 cell line p53 overexpression slightly slowed down the progression through S phase in cells treated with methotrexate, decreased the cyclin B1 expression only after 24 h, and failed to sustain the G2 arrest after treatment with cisplatin alone. Instead, it increased the population of S phase cells that were not actively synthesizing DNA, sustained cyclin B1 expression and allowed the G2 cells to progress through mitosis. This study demonstrates that adenovirally mediated p53 overexpression at sub-cytotoxic levels enhanced the activity of low doses of cisplatin and methotrexate in HEp-2 and CAL 27 cells through changes in the cell cycle. However, the mechanisms of these effects differ depending on the genetic context and

A Collection of Technical Studies Completed for the Computer-Aided Acquisition and Logistic Support (CALS) Program Fiscal Year 1988. Volume 1. Text, Security and Data Management

DTIC Science & Technology

1991-03-01

management methodologies claim to be "expert systems" with security intelligence built into them to I derive a body of both facts and speculative data ... Data Administration considerations . III -21 IV. ARTIFICIAL INTELLIGENCE . .. .. .. . .. IV - 1 A. Description of Technologies . . . . . .. IV - 1 1...as intelligent gateways, wide area networks, and distributed databases for the distribution of logistics products. The integrity of CALS data and the

BLDG. 9A - EGRESS TRAINING - JSC

NASA Image and Video Library

1978-09-11

S78-34927 (31 Aug. 1978) --- Astronaut C. Gordon Fullerton, one of a group of eight astronauts named to fly the first few orbital flight tests of the space transportation system, gets ready to participate in a training session for emergency egress from a space shuttle vehicle at the launch pad. He is wearing a USAF modified high altitude pressure garment like those to be worn by shuttle crew members at takeoff and landing. Photo credit: NASA NOTE: Since this photograph was made, astronaut C. Gordon Fullerton was named pilot of STS-3, scheduled for launch in early spring of 1982.

Studies for the electro-magnetic calorimeter SplitCal for the SHiP experiment at CERN with shower direction reconstruction capability

NASA Astrophysics Data System (ADS)

Bonivento, Walter M.

2018-02-01

This paper describes the basic ideas and the first simulation results of a new electro-magnetic calorimeter concept, named SplitCal, aimed at optimising the measurement of photon direction in fixed-target experiment configuration, with high photon detection efficiency. This calorimeter was designed for the invariant mass reconstruction of axion-like particles decaying into two photons in the mass range 200 MeV to 1 GeV for the proposed proton beam dump experiment SHiP at CERN. Preliminary results indicate that angular resolutions better than obtained by past experiments can be achieved with this design. An implementation of this concept with real technologies is under study.

Corrigendum to Aerosol impacts on California winter clouds and precipitation during CalWater 2011: local pollution versus long-range transported dust published in Atmos. Chem. Phys., 14, 81–101, 2014

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fan, Jiwen; Leung, Lai-Yung R.; DeMott, Paul J.

2014-05-01

In the paper “Aerosol impacts on California winter clouds and precipitation during CalWater 2011: local pollution versus long-range transported dust” by J. Fan et al., wrong versions of Fig. 8 and Fig. 12 were published. Please find the correct figures below.

An Australian contribution to CryoSat-II cal/val in East Antarctica including the Totten glacier region

NASA Astrophysics Data System (ADS)

Watson, C. S.; Burgette, R. J.; Tregoning, P.; Coleman, R.; Roberts, J.; Lieser, J. L.; Fricker, H. A.; Legresy, B.

2010-12-01

The Australian TOT-Cal project seeks to provide a contribution to the calibration and validation of the CryoSat-II mission over two adjacent important regions in East Antarctica. The first focuses on the Totten glacier, arguably one of the most important outlet glaciers in the East Antarctic, known to be undergoing significant surface lowering. The second includes the coastal slope regions behind Casey station and up on the plateau areas near Law Dome where significant spatial variation in annual accumulation is known to occur. The 2010/11 austral summer is the first field season for this project, with fieldwork to be underway at the time of the AGU FM10. In this poster, we present our current field activities and forward plans for the 2011/12 season. Our field campaign includes three components. A total of six in-situ GPS sites will be deployed over the summer period throughout the Law Dome / Totten Glacier region. These sites will facilitate the computation of the integrated water vapour content of the atmosphere, enabling an assessment against the ECMWF product used in the CyroSat-II data stream. The GPS sites also serve to provide reference stations for the AWI Polar-5 aircraft that will fly over the study area equipped with a scanning LiDAR and the ESA ASIRAS instrument. Finally, a series of kinematic GPS transects, corner cube reflector placements and surface density measurements will be undertaken from our field camp on the western flank of Law Dome to provide high resolution ground measurements for cal/val activities. In a separate project, Antarctic sea ice freeboard measurements will also contribute to the calibration and validation efforts by the Australian Antarctic program. In November 2010, the first set of such measurements will be carried out in the East Antarctic sea ice zone between 77 and 90 degrees East. The primary measurement tools for this campaign will include helicopter mounted scanning LiDAR and aerial photography, combined with in

The application of Flow Cytometry to the study of ancient agriculture: Evidence for Mesolithic farming in Northern Britain 7200 Cal yr BP.

NASA Astrophysics Data System (ADS)

Jones, Richard; Tennant, Richard; Hatton, Jackie; Lee, Rob; Love, John

2017-04-01

The onset of agriculture in the UK, (the Mesolithic-Neolithic transition 6000 - 5500 Cal yr BP), has commonly been viewed as the end point of a cultural and technological wave that began in Eastern Europe on the Hungarian Plain 7500 Cal yr BP. This view is not without its critics, due in part to the uncertainty regarding the timing and rate of expansion and the difficulty in identifying the point at which agriculture first arrived in a particular location. Evidence for potential 'episodes' of Mesolithic agricultural activity in the UK has been identified in the UK pollen record, but this data is very tentative. Cereal pollen is typically present in very low concentrations (requiring very large, time consuming counts) and differentiating early cereal pollen from local grasses is very problematic, particularly in areas where the local grasses were domesticated. We present a multi-proxy record from Mere Tarn (54°8'12.09" N 3°7'24.28"W), 2km from the Morecambe Bay coast in South Cumbria, UK; a region with a long history of human occupation extending back into the Palaeolithic. A lacustrine core spanning the Mesolithic and Neolithic has been analysed using a combination of 'traditional' pollen analysis, Flow Cytometry and ancient DNA (aDNA). Flow Cytometry is employed to increase the concentration of cereal type grains in a sample, whilst also providing a more 'targeted' sample for aDNA analysis. The results so far provide clear evidence for an early phase of 'Mesolithic' agriculture in the catchment, spanning only two centuries ( 7300 to 7100 Cal yr BP). This phase is characterised by the occurrence of large cereal type grains (> 38µm), evidence for woodland clearance and the expansion of key anthropogenic indicators such as P. lanceolata. It occurred over 1600 years before the main transition into permanent and intensive agriculture in the catchment, at a time of significant changes in regional climate and sea-level. The results from Mere Tarn provide the earliest

Pre-STS-3 press conference held at the JSC public affairs facility

NASA Technical Reports Server (NTRS)

1982-01-01

Astronauts Jack R. Lousma, center, and C. Gordon Fullerton, left, respond to a visual display of the Columbia and its remote manipulator system in space during a pre-STS-3 press conference. Dr. John Lawrence, public information specialist, is at the far right (25903); Astronaut Lousma, listens as a newsman directs a question his way. In the background is the STS-3 mission logo (25904); Astronaut Fullerton uses an electronic pointer to localize an area on a prjected visual of the OSS payload package to be carried in the cargo bay of the Columbia on STS-3. On far right is Dr. Lawrence (25905).

Evaluation of the airborne quantum cascade laser spectrometer (QCLS) measurements of the carbon and greenhouse gas suite - CO2, CH4, N2O, and CO - during the CalNex and HIPPO campaigns

NASA Astrophysics Data System (ADS)

Santoni, G. W.; Daube, B. C.; Kort, E. A.; Jiménez, R.; Park, S.; Pittman, J. V.; Gottlieb, E.; Xiang, B.; Zahniser, M. S.; Nelson, D. D.; McManus, J. B.; Peischl, J.; Ryerson, T. B.; Holloway, J. S.; Andrews, A. E.; Sweeney, C.; Hall, B.; Hintsa, E. J.; Moore, F. L.; Elkins, J. W.; Hurst, D. F.; Stephens, B. B.; Bent, J.; Wofsy, S. C.

2014-06-01

We present an evaluation of aircraft observations of the carbon and greenhouse gases CO2, CH4, N2O, and CO using a direct-absorption pulsed quantum cascade laser spectrometer (QCLS) operated during the HIPPO and CalNex airborne experiments. The QCLS made continuous 1 Hz measurements with 1σ Allan precisions of 20, 0.5, 0.09, and 0.15 ppb for CO2, CH4, N2O, and CO, respectively, over > 500 flight hours on 79 research flights. The QCLS measurements are compared to two vacuum ultraviolet (VUV) CO instruments (CalNex and HIPPO), a cavity ring-down spectrometer (CRDS) measuring CO2 and CH4 (CalNex), two broadband non-dispersive infrared (NDIR) spectrometers measuring CO2 (HIPPO), two onboard gas chromatographs measuring a variety of chemical species including CH4, N2O, and CO (HIPPO), and various flask-based measurements of all four species. QCLS measurements are tied to NOAA and WMO standards using an in-flight calibration system, and mean differences when compared to NOAA CCG flask data over the 59 HIPPO research flights were 100, 1, 1, and 2 ppb for CO2, CH4, N2O, and CO, respectively. The details of the end-to-end calibration procedures and the data quality assurance and quality control (QA/QC) are presented. Specifically, we discuss our practices for the traceability of standards given uncertainties in calibration cylinders, isotopic and surface effects for the long-lived greenhouse gas tracers, interpolation techniques for in-flight calibrations, and the effects of instrument linearity on retrieved mole fractions.

Emission estimates of HCFCs and HFCs in California from the 2010 CalNex study

NASA Astrophysics Data System (ADS)

Barletta, Barbara; Carreras-Sospedra, Marc; Cohan, Alex; Nissenson, Paul; Dabdub, Donald; Meinardi, Simone; Atlas, Elliot; Lueb, Rich; Holloway, John S.; Ryerson, Thomas B.; Pederson, James; VanCuren, Richard A.; Blake, Donald R.

2013-02-01

The CalNex 2010 (California Research at the Nexus of Air Quality and Climate Change) study was designed to evaluate the chemical composition of air masses over key source regions in California. During May to June 2010, air samples were collected on board a National Oceanic and Atmospheric Administration (NOAA) WP-3D aircraft over the South Coast Air Basin of California (SoCAB) and the Central Valley (CV). This paper analyzes six effective greenhouse gases—chlorodifluoromethane (HCFC-22), 1,1-dichloro-1-fluoroethane (HCFC-141b), 1-chloro-1,1-difluoroethane (HCFC-142b), 2-chloro-1,1,1,2-tetrafluoroethane (HCFC-124), 1,1,1,2-tetrafluoroethane (HFC-134a), and 1,1-difluoroethane (HFC-152a)—providing the most comprehensive characterization of chlorofluorocarbon (CFC) replacement compound emissions in California. Concentrations of measured HCFCs and HFCs are enhanced greatly throughout the SoCAB and CV, with highest levels observed in the SoCAB: 310 ± 92 pptv for HCFC-22, 30.7 ± 18.6 pptv for HCFC-141b, 22.9 ± 2.0 pptv for HCFC-142b, 4.86 ± 2.56 pptv for HCFC-124, 109 ± 46.4 pptv for HFC-134a, and 91.2 ± 63.9 pptv for HFC-152a. Annual emission rates are estimated for all six compounds in the SoCAB using the measured halocarbon to carbon monoxide (CO) mixing ratios and CO emissions inventories. Emission rates of 3.05 ± 0.70 Gg for HCFC-22, 0.27 ± 0.07 Gg for HCFC-141b, 0.06 ± 0.01 Gg for HCFC-142b, 0.11 ± 0.03 Gg for HCFC-124, 1.89 ± 0.43 Gg for HFC-134a, and 1.94 ± 0.45 Gg for HFC-152b for the year 2010 are calculated for the SoCAB. These emissions are extrapolated from the SoCAB region to the state of California using population data. Results from this study provide a baseline emission rate that will help future studies determine if HCFC and HFC mitigation strategies are successful.

Constraints on primary and secondary particulate carbon sources using chemical tracer and 14C methods during CalNex-Bakersfield

NASA Astrophysics Data System (ADS)

Sheesley, Rebecca J.; Nallathamby, Punith Dev; Surratt, Jason D.; Lee, Anita; Lewandowski, Michael; Offenberg, John H.; Jaoui, Mohammed; Kleindienst, Tadeusz E.

2017-10-01

The present study investigates primary and secondary sources of organic carbon for Bakersfield, CA, USA as part of the 2010 CalNex study. The method used here involves integrated sampling that is designed to allow for detailed and specific chemical analysis of particulate matter (PM) in the Bakersfield airshed. To achieve this objective, filter samples were taken during thirty-four 23-hr periods between 19 May and 26 June 2010 and analyzed for organic tracers by gas chromatography - mass spectrometry (GC-MS). Contributions to organic carbon (OC) were determined by two organic tracer-based techniques: primary OC by chemical mass balance and secondary OC by a mass fraction method. Radiocarbon (14C) measurements of the total organic carbon were also made to determine the split between the modern and fossil carbon and thereby constrain unknown sources of OC not accounted for by either tracer-based attribution technique. From the analysis, OC contributions from four primary sources and four secondary sources were determined, which comprised three sources of modern carbon and five sources of fossil carbon. The major primary sources of OC were from vegetative detritus (9.8%), diesel (2.3%), gasoline (<1.0%), and lubricating oil impacted motor vehicle exhaust (30%); measured secondary sources resulted from isoprene (1.5%), α-pinene (<1.0%), toluene (<1.0%), and naphthalene (<1.0%, as an upper limit) contributions. The average observed organic carbon (OC) was 6.42 ± 2.33 μgC m-3. The 14C derived apportionment indicated that modern and fossil components were nearly equivalent on average; however, the fossil contribution ranged from 32 to 66% over the five week campaign. With the fossil primary and secondary sources aggregated, only 25% of the fossil organic carbon could not be attributed. Whereas, nearly 80% of the modern carbon could not be attributed to primary and secondary sources accessible to this analysis, which included tracers of biomass burning, vegetative

Constraints on primary and secondary particulate carbon sources using chemical tracer and 14C methods during CalNex-Bakersfield

PubMed Central

Sheesley, Rebecca J.; Nallathamby, Punith Dev; Surratt, Jason D.; Lee, Anita; Lewandowski, Michael; Offenberg, John H.; Jaoui, Mohammed; Kleindienst, Tadeusz E.

2018-01-01

The present study investigates primary and secondary sources of organic carbon for Bakersfield, CA, USA as part of the 2010 CalNex study. The method used here involves integrated sampling that is designed to allow for detailed and specific chemical analysis of particulate matter (PM) in the Bakersfield airshed. To achieve this objective, filter samples were taken during thirty-four 23-hr periods between 19 May and 26 June 2010 and analyzed for organic tracers by gas chromatography – mass spectrometry (GC-MS). Contributions to organic carbon (OC) were determined by two organic tracer-based techniques: primary OC by chemical mass balance and secondary OC by a mass fraction method. Radiocarbon (14C) measurements of the total organic carbon were also made to determine the split between the modern and fossil carbon and thereby constrain unknown sources of OC not accounted for by either tracer-based attribution technique. From the analysis, OC contributions from four primary sources and four secondary sources were determined, which comprised three sources of modern carbon and five sources of fossil carbon. The major primary sources of OC were from vegetative detritus (9.8%), diesel (2.3%), gasoline (<1.0%), and lubricating oil impacted motor vehicle exhaust (30%); measured secondary sources resulted from isoprene (1.5%), α-pinene (<1.0%), toluene (<1.0%), and naphthalene (<1.0%, as an upper limit) contributions. The average observed organic carbon (OC) was 6.42 ± 2.33 μgC m−3. The 14C derived apportionment indicated that modern and fossil components were nearly equivalent on average; however, the fossil contribution ranged from 32-66% over the five week campaign. With the fossil primary and secondary sources aggregated, only 25% of the fossil organic carbon could not be attributed. Whereas, nearly 80% of the modern carbon could not be attributed to primary and secondary sources accessible to this analysis, which included tracers of biomass burning, vegetative

The Diagnostic Implications of Two Cases of Known Rheumatoid Arthritis from the CAL Milano Cemetery Skeletal Collection.

PubMed

Biehler-Gomez, Lucie; Cattaneo, Cristina

2018-04-23

Rheumatoid arthritis (RA) is the most common erosive arthropathy and is of particular interest to forensic sciences. However, its diagnosis on bones remains challenging. We examined two skeletons from the CAL Milano Cemetery Skeletal Collection diagnosed with the pathology during life, to test the validity of the diagnostic criteria on bones. The first showed typical lesions of RA described in the literature. The second exhibited secondary osteoarthrosis, suggesting long-standing RA. A differential diagnosis including all four seronegative spondyloarthropathies, erosive osteoarthritis, gout and neuropathic arthropathy was also considered. Both shared common features consistent with the literature: symmetric erosions of bones in the hands, wrists and elbows, sparing of the distal interphalangeal joints, and the absence of sacroiliac and spinal fusion. Given the paucity of studies on known RA skeletons, these results strengthen the criteria for diagnosis. This research is, to our knowledge, the first study on identified and known individuals with RA. © 2018 American Academy of Forensic Sciences.

Hydroxyl and Hydroperoxy Chemistry at the CalNex-LA 2010 Site: Measurements and Modeling

NASA Astrophysics Data System (ADS)

Griffith, S. M.; Hansen, R. F.; Dusanter, S.; Stevens, P. S.; Gilman, J. B.; Kuster, W. C.; Veres, P. R.; Graus, M.; Warneke, C.; De Gouw, J. A.; Young, C. J.; Washenfelder, R. A.; Brown, S. S.; Flynn, J. H.; Alvarez, S. L.; Grossberg, N.; Lefer, B. L.; Rappenglueck, B.; Mielke, L. H.; Osthoff, H. D.

2011-12-01

Hydroxyl (OH) and hydroperoxy (HO2) radicals are key species in the atmosphere driving the oxidation of organic trace gases leading to the production of ozone and secondary organic aerosols. Previous measurements of these radicals in urban environments have shown similarities and differences across sites due to differing levels of nitrogen oxides (NOx) and volatile organic compounds (VOCs), and the control strategies for dealing with these chemical species. Understanding the free radical chemistry is essential for effectively regulating NOx and VOC emissions and controlling ozone and other secondary pollutants. Measurements of OH and HO2 radicals were made using a laser-induced fluorescence technique as part of the CalNex LA campaign during May-June, 2010. Median HOx (OH + HO2) concentrations, as well as HO2-to-OH ratios, were similar to previous measurements in other urban areas. An extensive suite of supporting measurements including photolysis rates, NOx, and other inorganic species, biogenic, aromatic, and other anthropogenic VOCs are used to constrain a zero-dimensional box model based on the Regional Atmospheric Chemistry Mechanism. Model comparisons provide details about the ability of commonly used chemical mechanisms to reproduce HOx production and loss rates, the radical cycling, and instantaneous O3 production rates in the Los Angeles area.

Nitrous acid chemistry in Los Angeles during the CalNex-LA experiment

NASA Astrophysics Data System (ADS)

Stutz, J.; Tsai, C.; Wong, K.; Pikelnaya, O.; Hurlock, S. C.; Young, C. J.; Veres, P. R.; Washenfelder, R. A.; Brown, S. S.; Flynn, J. H.; Grossberg, N.; Lefer, B. L.

2011-12-01

The role of nitrous acid, HONO, as an OH radical precursor during the early morning and during the day has received considerable attention over the past decade. Several studies have reported that HONO photolysis in the polluted boundary layer is the dominant source of OH in the early morning, and that it contributes up to 30% to the diurnally averaged primary OH formation. Despite the importance of HONO for boundary layer chemistry, our understanding of HONO sources is still incomplete. Laboratory studies suggest that HONO is formed by the conversion of NO2 on humid surfaces at night. As this process is too slow during the day, several photo-enhanced processes have been proposed that either accelerate the NO2 conversion, or involve other nitrogen species, such as HNO3. Field observations of vertical HONO and NO2 concentration profiles, together with accurate measurements of other nitrogen species and actinic flux measurements offer a unique opportunity to constrain the proposed HONO formation mechanisms. Here we present observations of HONO, NO2, and other parameters made by various instruments during the 2010 CalNex experiment on the east side of the Los Angeles basin. We will discuss the vertical profiles of HONO and NO2 measured by LP-DOAS, CEAS, CIMS, and photolytic conversion + CL with regard to the formation of HONO. The observations will be compared to 1D chemistry and transport model calculations to test various proposed formation mechanisms. We will discuss the most likely formation pathway of HONO and the potential impact of HONO on atmospheric chemistry in Los Angeles.

Supersaturation of Calcipotriene and Betamethasone Dipropionate in a Novel Aerosol Foam Formulation for Topical Treatment of Psoriasis Provides Enhanced Bioavailability of the Active Ingredients.

PubMed

Lind, Marianne; Nielsen, Kim Troensegaard; Schefe, Line Hollesen; Nørremark, Kasper; Eriksson, André Huss; Norsgaard, Hanne; Pedersen, Brian Thoning; Petersson, Karsten

2016-09-01

Previous studies have demonstrated the superior efficacy of a novel aerosol foam formulation of fixed combination calcipotriene 0.005% (Cal) and betamethasone dipropionate 0.064% (BD), compared with the ointment formulation. The aim of this study is to ascertain whether enhanced bioavailability of the active ingredients due to supersaturation and/or occlusive properties can explain the observed greater clinical efficacy. Solubility and evaporation experiments were conducted to examine the abilities of Cal/BD aerosol foam ingredients to create a supersaturated environment. Optical microscopy, Raman imaging and X-ray powder diffraction were used to examine the physical state of Cal and BD in the formulations after application, and determine whether a supersaturated state remained stable for clinically relevant time periods. In vitro skin penetration and ex vivo biomarker assays were conducted to compare the skin penetration and bioavailability of Cal and BD from the aerosol foam and ointment formulations, respectively. Occlusive properties were examined via transepidermal water loss. Solubility studies showed that Cal and BD solubility increased with increasing dimethyl ether (DME) content. Both active ingredients are completely dissolved in the final aerosol foam formulation. DME rapidly evaporates after spraying, and the amount was reduced to 0.5% of the initial amount after 2 min. This led to the formation of a supersaturated environment, where Cal and BD crystals were absent for at least 26 h after application. Cal/BD aerosol foam had significantly greater in vitro skin penetration and had increased bioavailability compared with Cal/BD ointment. Both formulations effectively occluded the skin. A stable supersaturated solution of Cal/BD in the aerosol foam leads to increased bioavailability and explains the improved clinical effect when compared to the Cal/BD ointment. The studies included in the paper are all conducted by LEO Pharma A/S or CROs on behalf of LEO

CAL3JHH: a Java program to calculate the vicinal coupling constants (3J H,H) of organic molecules.

PubMed

Aguirre-Valderrama, Alonso; Dobado, José A

2008-12-01

Here, we present a free web-accessible application, developed in the JAVA programming language for the calculation of vicinal coupling constant (3J(H,H)) of organic molecules with the H-Csp3-Csp3-H fragment. This JAVA applet is oriented to assist chemists in structural and conformational analyses, allowing the user to calculate the averaged 3J(H,H) values among conformers, according to its Boltzmann populations. Thus, the CAL3JHH program uses the Haasnoot-Leeuw-Altona equation, and, by reading the molecule geometry from a protein data bank (PDB) file format or from multiple pdb files, automatically detects all the coupled hydrogens, evaluating the data needed for this equation. Moreover, a "Graphical viewer" menu allows the display of the results on the 3D molecule structure, as well as the plotting of the Newman projection for the couplings.

Improved satellite and geospatial tools for pipeline operator decision support systems.

DOT National Transportation Integrated Search

2017-01-06

Under Cooperative Agreement No. OASRTRS-14-H-CAL, California Polytechnic State University San Luis Obispo (Cal Poly), partnered with C-CORE, MDA, PRCI, and Electricore to design and develop improved satellite and geospatial tools for pipeline operato...

Atmospheric River impacts in British Columbia and the Pacific Northwest on 22-24 January 2015 during the CalWater 2015 field campaign

NASA Astrophysics Data System (ADS)

Gaggini, N. G.; Spackman, J. R.; Neiman, P. J.; White, A. B.; Fairall, C. W.; Barnet, C.; Gambacorta, A.; Hughes, M.

2015-12-01

Over 30 dropsonde transects were performed across atmospheric rivers (ARs) over the eastern Pacific during CalWater 2015. An event in late January allowed first-of-its-kind coordinated dropsonde transects of an AR using the NOAA G-IV aircraft in tandem with the NOAA Ronald H. Brown (RHB), which observed the marine boundary layer during the passage of this major AR. Dropsonde data collected on 22 January 2015 sampled the early stages of the AR, when the AR began making landfall near Vancouver Island, British Columbia. At the same time the RHB collected precipitation and oceanic moisture flux measurements on the warm side of the AR. A second flight on 24 January 2015 sampled the later stages of the AR, again passing over the RHB stationed beneath the AR. During this later period, the AR axis of moisture shifted north-northeast and fanned out along the coast, affecting regions from Northern Washington to Southern Alaska. Multi-day landfalling AR conditions led to flooding in British Columbia and northern Washington. The influence of the coastal orography combined with the shift in AR orientation is examined to understand the orographic control of precipitation that triggered the flooding. In addition, cross section analysis of the AR using dropsonde and reanalysis data are used to better understand the synoptic influences, water vapor transport, and moisture evolution during the lifecycle of the AR. To gain greater insight into AR development and prolonged AR conditions that led to enhanced flooding, a comparison of aircraft and ship data from CalWater 2015 and NOAA Unique CrIS/ATMS Processing System (NUCAPS) retrievals (integrated water vapor, vertical temperature and moisture profiles, and an experimental ATMS-only rain rate product) will be compared for the 22-24 January period.

Pulse Height Analyzer Interfacing and Computer Programming in the Environmental Laser Propagation Project

DTIC Science & Technology

1976-06-01

United States Naval Postgraduate School, Monterey , California, 1974. 6. Anton , H., Elementary Linear Algebra , John Wiley & Sons, 1973. 7. Parrat, L. G...CONVERTER ln(laser & bias) PULSE HEIGHT ANALYZER © LINEAR AMPLIFIER SAMPLE TRIGGER OSCILLATOR early ln(laser & bias) SCINTILLOMETERS recent BACKGROUND...DEMODULATOR LASER CALIBRATION BOX LASER OR CAL VOLTAGE LOG CONVERTER LN (LASER OR CAL VOLT) LINEAR AMPLIFIER uLN (LASER OR CAL VOLT) PULSE HEIGHTEN ANALYZER V

State-of-the-art acute phase management of Kawasaki disease after 2017 scientific statement from the American Heart Association.

PubMed

Liu, Yi-Ching; Lin, Ming-Tai; Wang, Jou-Kou; Wu, Mei-Hwan

2018-03-30

Kawasaki disease (KD) has become the most common form of pediatric systemic vasculitis. Although patients with KD received intravenous immunoglobulin (IVIG) therapy, coronary arterial lesions (CALs) still occurred in 5%-10% of these patients during the acute stage. CALs may persist and even progress to stenosis or obstruction. Therefore, CALs following KD are currently the leading cause of acquired heart diseases in children. The etiology of CALs remains unknown despite more than four decades of research. Two unsolved problems are IVIG unresponsiveness and the diagnosis of incomplete KD. The two subgroups of KD patients with these problems have a high risk of CAL. In April 2017, the American Heart Association (AHA) updated the guidelines for the diagnosis, treatment, and long-term management of KD. Compared with the previous KD guidelines published in 2004, the new guidelines provide solutions to the aforementioned two problems and emphasize risk stratification by using coronary artery Z score systems, as well as coronary severity-based management and long-term follow-up. Therefore, in this study, we merged the AHA Scientific Statement in 2017 with recent findings for Taiwanese KD patients to provide potential future care directions for Taiwanese patients with KD. Copyright © 2018. Published by Elsevier B.V.

Extending MAM5 Meta-Model and JaCalIV E Framework to Integrate Smart Devices from Real Environments.

PubMed

Rincon, J A; Poza-Lujan, Jose-Luis; Julian, V; Posadas-Yagüe, Juan-Luis; Carrascosa, C

2016-01-01

This paper presents the extension of a meta-model (MAM5) and a framework based on the model (JaCalIVE) for developing intelligent virtual environments. The goal of this extension is to develop augmented mirror worlds that represent a real and virtual world coupled, so that the virtual world not only reflects the real one, but also complements it. A new component called a smart resource artifact, that enables modelling and developing devices to access the real physical world, and a human in the loop agent to place a human in the system have been included in the meta-model and framework. The proposed extension of MAM5 has been tested by simulating a light control system where agents can access both virtual and real sensor/actuators through the smart resources developed. The results show that the use of real environment interactive elements (smart resource artifacts) in agent-based simulations allows to minimize the error between simulated and real system.

Extending MAM5 Meta-Model and JaCalIV E Framework to Integrate Smart Devices from Real Environments

PubMed Central

2016-01-01

This paper presents the extension of a meta-model (MAM5) and a framework based on the model (JaCalIVE) for developing intelligent virtual environments. The goal of this extension is to develop augmented mirror worlds that represent a real and virtual world coupled, so that the virtual world not only reflects the real one, but also complements it. A new component called a smart resource artifact, that enables modelling and developing devices to access the real physical world, and a human in the loop agent to place a human in the system have been included in the meta-model and framework. The proposed extension of MAM5 has been tested by simulating a light control system where agents can access both virtual and real sensor/actuators through the smart resources developed. The results show that the use of real environment interactive elements (smart resource artifacts) in agent-based simulations allows to minimize the error between simulated and real system. PMID:26926691

Interfacial microstructure in a B{sub 4}C/Al composite fabricated by pressureless infiltration.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Luo, Z.; Song, Y.; Zhang, S.

In this work, B{sub 4}C particulate-reinforced Al composite was fabricated by a pressureless infiltration technique, and its interfacial microstructure was studied in detail by X-ray diffraction as well as by scanning and transmission electron microscopy. The B{sub 4}C phase was unstable in Al melt during the infiltration process, forming AlB{sub 10}-type AlB{sub 24}C{sub 4} or Al{sub 2.1}B{sub 51}C{sub 8} as a major reactant phase. The Al matrix was large grains (over 10 {micro}m), which had no definite orientation relationships (ORs) with the randomly orientated B{sub 4}C or its reactant particles, except for possible nucleation sites with {l_brace}011{r_brace}{sub B{sub 4}C} almostmore » parallel to {l_brace}111{r_brace}{sub Al} at a deviation angle of 1.5 deg. Both B{sub 4}C-Al and reactant-Al interfaces are semicoherent and free of other phases. A comparison was made with the SiC/Al composite fabricated similarly by the pressureless infiltration. It was suggested that the lack of ORs between the Al matrix and reinforced particles, except for possible nucleation sites, is the common feature of the composites prepared by the infiltration method.« less

Understanding sources of organic aerosol during CalNex-2010 using the CMAQ-VBS

NASA Astrophysics Data System (ADS)

Woody, M. C.; Baker, K. R.; Hayes, P. L.; Jimenez, J. L.; Koo, B.; Pye, H. O. T.

2015-10-01

Community Multiscale Air Quality (CMAQ) model simulations utilizing the volatility basis set (VBS) treatment for organic aerosols (CMAQ-VBS) were evaluated against measurements collected at routine monitoring networks (Chemical Speciation Network (CSN) and Interagency Monitoring of Protected Visual Environments (IMPROVE)) and those collected during the 2010 California at the Nexus of Air Quality and Climate Change (CalNex) field campaign to examine important sources of organic aerosol (OA) in southern California. CMAQ-VBS (OA lumped by volatility, semivolatile POA) underpredicted total organic carbon (OC) at CSN (-25.5 % Normalized Median Bias (NMdnB)) and IMPROVE (-63.9 % NMdnB) locations and total OC was underpredicted to a greater degree compared to the CMAQ-AE6 (9.9 and -55.7 % NMdnB, respectively; semi-explicit OA treatment, SOA lumped by parent hydrocarbon, nonvolatile POA). However, comparisons to aerosol mass spectrometer (AMS) measurements collected at Pasadena, CA indicated that CMAQ-VBS better represented the diurnal profile and the primary/secondary split of OA. CMAQ-VBS secondary organic aerosol (SOA) underpredicted the average measured AMS oxygenated organic aerosol (OOA, a surrogate of SOA) concentration by a factor of 5.2 (4.7 μg m-3 measured vs. 0.9 μg m-3 modeled), a considerable improvement to CMAQ-AE6 SOA predictions, which were approximately 24× lower than the average AMS OOA concentration. We use two new methods, based on species ratios and on a simplified SOA parameterization from the observations, to apportion the SOA underprediction for CMAQ-VBS to too slow photochemical oxidation (estimated as 1.5× lower than observed at Pasadena using - log (NOx: NOy)), low intrinsic SOA formation efficiency (low by 1.6 to 2× for Pasadena), and too low emissions or too high dispersion for the Pasadena site (estimated to be 1.6 to 2.3× too low/high). The first and third factors will be similar for CMAQ-AE6, while the intrinsic SOA formation

Understanding sources of organic aerosol during CalNex-2010 using the CMAQ-VBS

NASA Astrophysics Data System (ADS)

Woody, Matthew C.; Baker, Kirk R.; Hayes, Patrick L.; Jimenez, Jose L.; Koo, Bonyoung; Pye, Havala O. T.

2016-03-01

Community Multiscale Air Quality (CMAQ) model simulations utilizing the traditional organic aerosol (OA) treatment (CMAQ-AE6) and a volatility basis set (VBS) treatment for OA (CMAQ-VBS) were evaluated against measurements collected at routine monitoring networks (Chemical Speciation Network (CSN) and Interagency Monitoring of Protected Visual Environments (IMPROVE)) and those collected during the 2010 California at the Nexus of Air Quality and Climate Change (CalNex) field campaign to examine important sources of OA in southern California. Traditionally, CMAQ treats primary organic aerosol (POA) as nonvolatile and uses a two-product framework to represent secondary organic aerosol (SOA) formation. CMAQ-VBS instead treats POA as semivolatile and lumps OA using volatility bins spaced an order of magnitude apart. The CMAQ-VBS approach underpredicted organic carbon (OC) at IMPROVE and CSN sites to a greater degree than CMAQ-AE6 due to the semivolatile POA treatment. However, comparisons to aerosol mass spectrometer (AMS) measurements collected at Pasadena, CA, indicated that CMAQ-VBS better represented the diurnal profile and primary/secondary split of OA. CMAQ-VBS SOA underpredicted the average measured AMS oxygenated organic aerosol (OOA, a surrogate for SOA) concentration by a factor of 5.2, representing a considerable improvement to CMAQ-AE6 SOA predictions (factor of 24 lower than AMS). We use two new methods, one based on species ratios (SOA/ΔCO and SOA/Ox) and another on a simplified SOA parameterization, to apportion the SOA underprediction for CMAQ-VBS to slow photochemical oxidation (estimated as 1.5 × lower than observed at Pasadena using -log(NOx : NOy)), low intrinsic SOA formation efficiency (low by 1.6 to 2 × for Pasadena), and low emissions or excessive dispersion for the Pasadena site (estimated to be 1.6 to 2.3 × too low/excessive). The first and third factors are common to CMAQ-AE6, while the intrinsic SOA formation efficiency for that model is

Understanding sources of organic aerosol during CalNex-2010 using the CMAQ-VBS

DOE PAGES

Woody, Matthew C.; Baker, Kirk R.; Hayes, Patrick L.; ...

2016-03-29

In this paper, Community Multiscale Air Quality (CMAQ) model simulations utilizing the traditional organic aerosol (OA) treatment (CMAQ-AE6) and a volatility basis set (VBS) treatment for OA (CMAQ-VBS) were evaluated against measurements collected at routine monitoring networks (Chemical Speciation Network (CSN) and Interagency Monitoring of Protected Visual Environments (IMPROVE)) and those collected during the 2010 California at the Nexus of Air Quality and Climate Change (CalNex) field campaign to examine important sources of OA in southern California. Traditionally, CMAQ treats primary organic aerosol (POA) as nonvolatile and uses a two-product framework to represent secondary organic aerosol (SOA) formation. CMAQ-VBS insteadmore » treats POA as semivolatile and lumps OA using volatility bins spaced an order of magnitude apart. The CMAQ-VBS approach underpredicted organic carbon (OC) at IMPROVE and CSN sites to a greater degree than CMAQ-AE6 due to the semivolatile POA treatment. However, comparisons to aerosol mass spectrometer (AMS) measurements collected at Pasadena, CA, indicated that CMAQ-VBS better represented the diurnal profile and primary/secondary split of OA. CMAQ-VBS SOA underpredicted the average measured AMS oxygenated organic aerosol (OOA, a surrogate for SOA) concentration by a factor of 5.2, representing a considerable improvement to CMAQ-AE6 SOA predictions (factor of 24 lower than AMS). We use two new methods, one based on species ratios (SOA/ΔCO and SOA/O x) and another on a simplified SOA parameterization, to apportion the SOA underprediction for CMAQ-VBS to slow photochemical oxidation (estimated as 1.5 × lower than observed at Pasadena using -log(NO x:NO y)), low intrinsic SOA formation efficiency (low by 1.6 to 2 × for Pasadena), and low emissions or excessive dispersion for the Pasadena site (estimated to be 1.6 to 2.3 × too low/excessive). The first and third factors are common to CMAQ-AE6, while the intrinsic SOA formation

Noise dependence with pile-up in the ATLAS Tile Calorimeter. Pile-up noise studies in the ATLAS TileCal calorimeter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Araque, J.P.

The Tile Calorimeter, TileCal, is the central hadronic calorimeter of the ATLAS experiment, positioned between the electromagnetic calorimeter and the muon chambers. It comprises alternating layers of steel (as absorber material) and plastic (as active material), known as tiles. Between 2009 and 2012, the LHC has performed better than expected producing proton-proton collisions at a very high rate. These conditions are really challenging when dealing with the energy measurements in the calorimeter since not only the energy from an interesting event will be measured but a component coming from other collisions, which are difficult to distinguish from the interesting one,more » will also be present. This component is referred to as pile-up noise. Studies carried out to better understand how pile-up affects calorimeter noise under different circumstances are described. (author)« less

Growth of Accountable Care Organizations in California: Number, Characteristics, and State Regulation.

PubMed

Fulton, Brent D; Pegany, Vishaal; Keolanui, Beth; Scheffler, Richard M

2015-08-01

Accountable care organizations (ACOs) result in physician organizations' and hospitals' receiving risk-based payments tied to costs, health care quality, and patient outcomes. This article (1) describes California ACOs within Medicare, the commercial market, and Medi-Cal and the safety net; (2) discusses how ACOs are regulated by the California Department of Managed Health Care and the California Department of Insurance; and (3) analyzes the increase of ACOs in California using data from Cattaneo and Stroud. While ACOs in California are well established within Medicare and the commercial market, they are still emerging within Medi-Cal and the safety net. Notwithstanding, the state has not enacted a law or issued a regulation specific to ACOs; they are regulated under existing statutes and regulations. From August 2012 to February 2014, the number of lives covered by ACOs increased from 514,100 to 915,285, representing 2.4 percent of California's population, including 10.6 percent of California's Medicare fee-for-service beneficiaries and 2.3 percent of California's commercially insured lives. By emphasizing health care quality and patient outcomes, ACOs have the potential to build and improve on California's delegated model. If recent trends continue, ACOs will have a greater influence on health care delivery and financial risk sharing in California. Copyright © 2015 by Duke University Press.

Benchmarking electronic-state excitation cross sections for electron-N{sub 2} collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kato, Hidetoshi; Suzuki, Daisuke; Ohkawa, Mizuha

2010-04-15

We report differential cross sections for electron impact excitation of the a {sup 1{Pi}}{sub g}, C {sup 3{Pi}}{sub u}, E {sup 3{Sigma}}{sub g}{sup +}, a{sup ''} {sup 1{Sigma}}{sub g}{sup +}, b {sup 1{Pi}}{sub u}, c{sub 3} {sup 1{Pi}}{sub u}, o{sub 3} {sup 1{Pi}}{sub u}, b{sup '} {sup 1{Sigma}}{sub u}{sup +}, c{sub 4}{sup '} {sup 1{Sigma}}{sub u}{sup +}, G {sup 3{Pi}}{sub u}, and F {sup 3{Pi}}{sub u} electronic states in N{sub 2}. The incident electron energies are 20, 30, and 40 eV, while the scattered electron angles are 10 deg. and 20 deg. These kinematic conditions were specifically targeted in ordermore » to try and shed new light on the worrying discrepancies that exist in the literature for the a {sup 1{Pi}}{sub g}, C {sup 3{Pi}}{sub u}, E {sup 3{Sigma}}{sub g}{sup +}, and a{sup ''} {sup 1{Sigma}}{sub g}{sup +} cross sections, and in general the present measurements confirm that those from the more recent results of the University of California, Fullerton, and the Jet Propulsion Laboratory [M. A. Khakoo, P. V. Johnson, I. Ozkay, P. Yan, S. Trajmar, and I. Kanik, Phys. Rev. A 71, 062703 (2005); C. P. Malone, P. V. Johnson, I. Kanik, B. Ajdari, and M. A. Khakoo, Phys. Rev. A 79, 032704 (2009)] are reliable. In addition, we provide a rigorous cross-check for the remaining seven electronic states, where the only recent comprehensive study is from Khakoo and colleagues [Phys. Rev. A 77, 012704 (2008)]. Here, however, some of those cross sections are confirmed and others are not, suggesting that further work is still needed.« less

Evaluation of New and Proposed Organic Aerosol Sources and Mechanisms using the Aerosol Modeling Testbed. MILAGRO, CARES, CalNex, BEACHON, and GVAX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hodzic, Alma; Jimenez, Jose L.

2015-04-09

This work investigated the formation and evolution of organic aerosols (OA) arising from anthropogenic and biogenic sources in a framework that combined state-of-the-science process and regional modeling, and their evaluation against advanced and emerging field measurements. Although OA are the dominant constituents of submicron particles, our understanding of their atmospheric lifecycle is limited, and current models fail to describe the observed amounts and properties of chemically formed secondary organic aerosols (SOA), leaving large uncertainties on the effects of SOA on climate. Our work has provided novel modeling constraints on sources, formation, aging and removal of SOA by investigating in particularmore » (i) the contribution of trash burning emissions to OA levels in a megacity, (ii) the contribution of glyoxal to SOA formation in aqueous particles in California during CARES/CalNex and over the continental U.S., (iii) SOA formation and regional growth over a pine forest in Colorado and its sensitivity to anthropogenic NOx levels during BEACHON, and the sensitivity of SOA to (iv) the sunlight exposure during its atmospheric lifetime, and to (v) changes in solubility and removal of organic vapors in the urban plume (MILAGRO, Mexico City), and over the continental U.S.. We have also developed a parameterization of water solubility for condensable organic gases produced from major anthropogenic and biogenic precursors based on explicit chemical modeling, and made it available to the wider community. This work used for the first time constraints from the explicit model GECKO-A to improve SOA representation in 3D regional models such as WRF-Chem.« less

How ion properties determine the stability of a lipase enzyme in ionic liquids: a molecular dynamics study.

PubMed

Klähn, Marco; Lim, Geraldine S; Wu, Ping

2011-11-07

The influence of eight different ionic liquid (IL) solvents on the stability of the lipase Candida antarctica lipase B (CAL-B) is investigated with molecular dynamics (MD) simulations. Considered ILs contain cations that are based either on imidazolium or guanidinium as well as nitrate, tetrafluoroborate or hexafluorophosphate anions. Partial unfolding of CAL-B is observed during high-temperature MD simulations and related changes of CAL-B regarding its radius of gyration, surface area, secondary structure, amount of solvent close to the backbone and interaction strength with the ILs are evaluated. CAL-B stability is influenced primarily by anions in the order NO(3)(-)≪ BF(4)(-) < PF(6)(-) of increasing stability, which agrees with experiments. Cations influence protein stability less than anions but still substantially. Long decyl side chains, polar methoxy groups and guanidinium-based cations destabilize CAL-B more than short methyl groups, other non-polar groups and imidazolium-based cations, respectively. Two distinct causes for CAL-B destabilization are identified: a destabilization of the protein surface is facilitated mostly by strong Coulomb interactions of CAL-B with anions that exhibit a localized charge and strong polarization as well as with polar cation groups. Surface instability is characterized by an unraveling of α-helices and an increase of surface area, radius of gyration and protein-IL total interaction strength of CAL-B, all of which describe a destabilization of the folded protein state. On the other hand, a destabilization of the protein core is facilitated when direct core-IL interactions are feasible. This is the case when long alkyl chains are involved or when particularly hydrophobic ILs induce major conformational changes that enable ILs direct access to the protein core. This core instability is characterized by a disintegration of β-sheets, diffusion of ions into CAL-B and increasing protein-IL van der Waals interactions. This

Nanoparticle Control of Void Formation and Expansion in Polymeric and Composite Systems

DTIC Science & Technology

2007-02-01

facilities of GloCal Network Corporation, a Delaware legal entity with facilities in Seattle, Washington. The team succeeded at performing work in the State of...Delaware and Washington concurrently. After December 1, 2006, Professor Seferis and his team will continue the research, exclusively through GloCal

MD-11 PCA - Research flight team egress

NASA Technical Reports Server (NTRS)

1995-01-01

This McDonnell Douglas MD-11 has parked on the flightline at NASA's Dryden Flight Research Center, Edwards, California, following its completion of the first and second landings ever performed by a transport aircraft under engine power only (on Aug. 29, 1995). The milestone flight, with NASA research pilot and former astronaut Gordon Fullerton at the controls, was part of a NASA project to develop a computer-assisted engine control system that enables a pilot to land a plane safely when its normal control surfaces are disabled. Coming down the steps from the aircraft are Gordon Fullerton (in front), followed by Bill Burcham, Propulsion Controlled Aircraft (PCA) project engineer at Dryden; NASA Dryden controls engineer John Burken; John Feather of McDonnell Douglas; and Drew Pappas, McDonnell Douglas' project manager for PCA.

A Glossary for Pre-Calculus

ERIC Educational Resources Information Center

Arnold, Bruce; Kracht, Brenda; Ross, Judy; Teegarden, Terrie; Tompkins, Maurice

2012-01-01

In the deconstruction of the California state standards for trigonometry, linear algebra and mathematical analysis for the Cal-PASS (California Partnership for Achieving Student Success) Content Standards Deconstruction projects, it became apparent that terms were used for which no definition was given. The San Diego Central Cal-PASS Math…

Validation of the state version questionnaire on autonomic regulation (state-aR) for cancer patients

PubMed Central

2011-01-01

Objectives Current quality of life inventories used in oncology mainly measure the effects of chemo- or radiotherapy alongside functional and role scales. A new approach is to measure the autonomic state of regulation with the trait-inventory of autonomic regulation (Trait-aR). Loss of Trait-aR has been shown in different medical conditions such as breast cancer (BC) but not in colorectal cancer patients (CRC). In this paper we report the validation of a new state autonomic regulation scale (State-aR) of the last week. Methods Study 1 included 114 participants: (41 women/16 men with cancer and 57 age- and gender-matched healthy people) to conduct a reliability-, factor- and validity-analysis. Concurrent and convergent validity was evaluated with Trait-aR, Fatigue-Numeri-cal-Scale, Hospital Anxiety and Depression Scale (HADS-D) and the self-regulation scale, 65 participants were retested. Study 2 completed 42 participants: 17 with BC and 25 with CRC receiving chemotherapy. The State-aR was administered prior, during and after chemotherapy for measuring responsiveness. Results The factor analysis loaded to four subscales of State-aR (rest-activity, orthostatic-circulatory, thermosweating and digestive regulation) with a: Cronbach-α rα = 0.77-0.83 and a test-retest-reliability rrt = 0.60-0.80. The sum- and sub scales correlated with their concurrent subscales in the Trait-aR (0.48-0.74) and with the sum-scale moderately with all convergent criteria (r = 0.41 --0.44; p < 0.001). During chemotherapy the State-aR-sum and rest-activity-scale decreased significantly compared to the change in the Trait-aR (p < 0.05). Conclusions These findings support that the state autonomic regulation scale has satisfactory to good reliability, good validity and acceptable responsiveness in the context of chemotherapy treatment. PMID:22024425

Radiative Effects of Carbonaceous and Inorganic Aerosols over California during CalNex and CARES: Observations versus Model Predictions

NASA Astrophysics Data System (ADS)

Vinoj, V.; Fast, J. D.; Liu, Y.

2012-12-01

Aerosols have been identified to be a major contributor to the uncertainty in understanding the present climate. Most of this uncertainty arises due to the lack of knowledge of their micro-physical and chemical properties as well as how to adequately represent their spatial and temporal distributions. Increased process level understanding can be achieved through carefully designed field campaigns and experiments. These measurements can be used to elucidate the aerosol properties, mixing, transport and transformation within the atmosphere and also to validate and improve models that include meteorology-aerosol-chemistry interactions. In the present study, the WRF-Chem model is used to simulate the evolution of carbonaceous and inorganic aerosols and their impact on radiation during May and June of 2010 over California when two field campaigns took place: the California Nexus Experiment (CalNex) and Carbonaceous Aerosol and Radiative Effects Study (CARES). We merged CalNex and CARES data along with data from operational networks such as, California Air Resources Board (CARB's) air quality monitoring network, the Interagency Monitoring of Protected Visual Environments (IMPROVE) network, the AErosol RObotic NETwork (AERONET), and satellites into a common dataset for the Aerosol Modeling Test bed. The resulting combined dataset is used to rigorously evaluate the model simulation of aerosol mass, size distribution, composition, and optical properties needed to understand uncertainties that could affect regional variations in aerosol radiative forcing. The model reproduced many of the diurnal, multi-day, and spatial variations of aerosols as seen in the measurements. However, regionally the performance varied with reasonably good agreement with observations around Los Angeles and Sacramento and poor agreement with observations in the vicinity of Bakersfield (although predictions aloft were much better). Some aerosol species (sulfate and nitrate) were better represented

78 FR 22869 - Southern California Gas Company; Notice of Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-17

...] Southern California Gas Company; Notice of Amendment Take notice that on March 29, 2013, Southern California Gas Company (``SoCalGas'') filed two amendments to its November 21, 2012, petition for rate approval. SoCalGas states that the first amendment is to implement, pursuant to section 284.123, the rates...

30 CFR 905.816 - Performance standards-Surface mining activities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.817 - Performance standards-Underground mining activities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.817 - Performance standards-Underground mining activities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.816 - Performance standards-Surface mining activities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.816 - Performance standards-Surface mining activities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.817 - Performance standards-Underground mining activities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.816 - Performance standards-Surface mining activities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

30 CFR 905.817 - Peformance standards-Underground mining activities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Quality Control Act, Cal. Pub. Res. Code section 13000 et seq.; the California Water Code section 1200 et seq.; the California Air Pollution Control Laws, Cal. Health & Safety Code section 39000 et seq.; the..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA...

Sentinel 2: implementation of the means and methods for the CAL/VAL commissioning phase

NASA Astrophysics Data System (ADS)

Trémas, Thierry L.; Déchoz, Cécile; Lacherade, Sophie; Nosavan, Julien; Petrucci, Beatrice; Martimort, P.; Isola, Claudia

2013-10-01

In partnership with the European Commission and in the frame of the Copernicus program, the European Space Agency (ESA) is developing the Sentinel-2 optical imaging mission devoted to the operational monitoring of land and coastal areas. The Sentinel-2 mission is based on a satellites constellation deployed in polar sun-synchronous orbit. Sentinel-2 will offer a unique combination of global coverage with a wide field of view (290km), a high revisit (5 days with two satellites), a high resolution (10m, 20m and 60m) and multi-spectral imagery (13 spectral bands in visible and shortwave infra-red domains). The first satellite is planned to be launched in late 2014. In this context, the Centre National d'Etudes Spatiales (CNES) supports ESA to insure the cal/val commissioning phase. This paper provides first, an overview of the Sentinel-2 system and the image products delivered by the ground processing. Then the paper will present the ground segment, presently under preparation at CNES, and the various devices that compose it : the GPP in charge of producing the level 1 files, the "radiometric unit" that processes sensitivity parameters, the "geometric unit" in charge of fitting the images on a reference map, MACCS that will produce Level 2A files (computing reflectances at the Bottom of Atmosphere) and the TEC-S2 that will coordinate all the previous software and drive a database in which will be gather the incoming Level 0 files and the processed Level 1 files.

Perspective: Maximum caliber is a general variational principle for dynamical systems

NASA Astrophysics Data System (ADS)

Dixit, Purushottam D.; Wagoner, Jason; Weistuch, Corey; Pressé, Steve; Ghosh, Kingshuk; Dill, Ken A.

2018-01-01

We review here Maximum Caliber (Max Cal), a general variational principle for inferring distributions of paths in dynamical processes and networks. Max Cal is to dynamical trajectories what the principle of maximum entropy is to equilibrium states or stationary populations. In Max Cal, you maximize a path entropy over all possible pathways, subject to dynamical constraints, in order to predict relative path weights. Many well-known relationships of non-equilibrium statistical physics—such as the Green-Kubo fluctuation-dissipation relations, Onsager's reciprocal relations, and Prigogine's minimum entropy production—are limited to near-equilibrium processes. Max Cal is more general. While it can readily derive these results under those limits, Max Cal is also applicable far from equilibrium. We give examples of Max Cal as a method of inference about trajectory distributions from limited data, finding reaction coordinates in bio-molecular simulations, and modeling the complex dynamics of non-thermal systems such as gene regulatory networks or the collective firing of neurons. We also survey its basis in principle and some limitations.

Perspective: Maximum caliber is a general variational principle for dynamical systems.

PubMed

Dixit, Purushottam D; Wagoner, Jason; Weistuch, Corey; Pressé, Steve; Ghosh, Kingshuk; Dill, Ken A

2018-01-07

We review here Maximum Caliber (Max Cal), a general variational principle for inferring distributions of paths in dynamical processes and networks. Max Cal is to dynamical trajectories what the principle of maximum entropy is to equilibrium states or stationary populations. In Max Cal, you maximize a path entropy over all possible pathways, subject to dynamical constraints, in order to predict relative path weights. Many well-known relationships of non-equilibrium statistical physics-such as the Green-Kubo fluctuation-dissipation relations, Onsager's reciprocal relations, and Prigogine's minimum entropy production-are limited to near-equilibrium processes. Max Cal is more general. While it can readily derive these results under those limits, Max Cal is also applicable far from equilibrium. We give examples of Max Cal as a method of inference about trajectory distributions from limited data, finding reaction coordinates in bio-molecular simulations, and modeling the complex dynamics of non-thermal systems such as gene regulatory networks or the collective firing of neurons. We also survey its basis in principle and some limitations.

Resting-state Brain Activity Changes Associated with Tardive Dyskinesia in Patients with Schizophrenia: Fractional Amplitude of Low-frequency Fluctuation Decreased in the Occipital Lobe.

PubMed

Zhang, Ping; Li, Yanli; Fan, Fengmei; Li, Chiang-Shan R; Luo, Xingguang; Yang, Fude; Yao, Yin; Tan, Yunlong

2018-06-19

We explored resting-state brain activity and its potential links to clinical parameters in schizophrenic patients with tardive dyskinesia (TD) using fractional amplitude of low-frequency fluctuations (fALFF). Resting-state functional magnetic resonance imaging data were acquired from 32 schizophrenic patients with TD (TD group), 31 without TD (NTD group), and 32 healthy controls (HC group). Clinical parameters including psychopathological symptoms, severity of TD, and cognitive function were assessed using the Positive and Negative Syndrome Scale, Abnormal Involuntary Movement Scale (AIMS), and Repeatable Battery for the Assessment of Neuropsychological Status, respectively. Pearson correlation analyses were performed to determine the relationship between the regions with altered fALFF values and clinical parameters in TD patients. The TD group showed decreased fALFF in the left middle occipital gyrus (MOG) and the right calcarine sulcus (CAL) compared to the HC group, and decreased fALFF in the left cuneus compared to the NTD group. In the TD group, fALFF values in the left MOG and the right CAL were correlated separately with the delayed memory score (r = 0.44, p = 0.027; r = 0.43, p = 0.028, respectively). The AIMS total score was negatively correlated to the visuospatial/constructional score (r = -0.53, p = 0.005). Our findings suggested that resting-state brain activity changes were associated with TD in schizophrenic patients. There was an association between the decreased brain activity in the occipital lobe and the delayed memory cognition impairment in this population. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

Comparing clinical attachment level and pocket depth for predicting periodontal disease progression in healthy sites of patients with chronic periodontitis using multi-state Markov models.

PubMed

Mdala, Ibrahimu; Olsen, Ingar; Haffajee, Anne D; Socransky, Sigmund S; Thoresen, Magne; de Blasio, Birgitte Freiesleben

2014-09-01

To understand degeneration of healthy sites and identify factors associated with disease progression in patients with chronic periodontitis. Data on healthy sites from 163 American and Swedish subjects were analysed using two-three-state (health, gingivitis, chronic periodontitis) Markov models based on bleeding on probing (BOP), and either clinical attachment level (CAL) + BOP or pocket depth (PD) + BOP. In 2 years, 10% (CAL + BOP) and 3% (PD + BOP) of healthy sites developed chronic periodontitis. On average, healthy sites remained healthy for 32 months before transiting in both models. Most transitions (87-97%) from health were to the gingivitis state. The expected duration of the gingivitis lesion was 4-5 months and sites recovered with a high probability (96-98%). Disease severity as measured by number of sites with CAL/PD > 4 mm at baseline and smoking, were associated with fast progression from health to chronic periodontitis within 6 months as were gingival redness in the PD + BOP model only. With age, the rate of disease progression to gingivitis decreased. Transition probabilities for gingivitis and chronic periodontitis were higher with CAL + BOP than with PD + BOP. Smoking and disease severity were significant predictors for fast progression. © 2014 The Authors. Journal of Clinical Periodontology Published by John Wiley & Sons Ltd.

Comparing clinical attachment level and pocket depth for predicting periodontal disease progression in healthy sites of patients with chronic periodontitis using multi-state Markov models

PubMed Central

Mdala, Ibrahimu; Olsen, Ingar; Haffajee, Anne D; Socransky, Sigmund S; Thoresen, Magne; de Blasio, Birgitte Freiesleben

2014-01-01

Aim To understand degeneration of healthy sites and identify factors associated with disease progression in patients with chronic periodontitis. Material and Methods Data on healthy sites from 163 American and Swedish subjects were analysed using two-three-state (health, gingivitis, chronic periodontitis) Markov models based on bleeding on probing (BOP), and either clinical attachment level (CAL) + BOP or pocket depth (PD) + BOP. Results In 2 years, 10% (CAL + BOP) and 3% (PD + BOP) of healthy sites developed chronic periodontitis. On average, healthy sites remained healthy for 32 months before transiting in both models. Most transitions (87–97%) from health were to the gingivitis state. The expected duration of the gingivitis lesion was 4–5 months and sites recovered with a high probability (96–98%). Disease severity as measured by number of sites with CAL/PD > 4 mm at baseline and smoking, were associated with fast progression from health to chronic periodontitis within 6 months as were gingival redness in the PD + BOP model only. With age, the rate of disease progression to gingivitis decreased. Conclusion Transition probabilities for gingivitis and chronic periodontitis were higher with CAL + BOP than with PD + BOP. Smoking and disease severity were significant predictors for fast progression. PMID:24888705

Trends in Ground-State Entropies for Transition Metal Based Hydrogen Atom Transfer Reactions

PubMed Central

Mader, Elizabeth A.; Manner, Virginia W.; Markle, Todd F.; Wu, Adam; Franz, James A.; Mayer, James M.

2009-01-01

Reported herein are thermochemical studies of hydrogen atom transfer (HAT) reactions involving transition metal H-atom donors MIILH and oxyl radicals. [FeII(H2bip)3]2+, [FeII(H2bim)3]2+, [CoII(H2bim)3]2+ and RuII(acac)2(py-imH) [H2bip = 2,2’-bi-1,4,5,6-tetrahydropyrimidine, H2bim = 2,2’-bi-imidazoline, acac = 2,4-pentandionato, py-imH = 2-(2’-pyridyl)-imidazole)] each react with TEMPO (2,2,6,6-tetramethyl-1-piperidinoxyl) or tBu3PhO• (2,4,6-tri-tert-butylphenoxyl) to give the deprotonated, oxidized metal complex MIIIL, and TEMPOH or tBu3PhOH. Solution equilibrium measurements for the reaction of [CoII(H2bim)3]2+ with TEMPO show a large, negative ground-state entropy for hydrogen atom transfer, −41 ± 2 cal mol−1 K−1. This is even more negative than the ΔSoHAT = −30 ± 2 cal mol−1 K−1 for the two iron complexes and the ΔSoHAT for RuII(acac)2(py-imH) + TEMPO, 4.9 ± 1.1 cal mol−1 K−1, as reported earlier. Calorimetric measurements quantitatively confirm the enthalpy of reaction for [FeII(H2bip)3]2+ + TEMPO, thus also confirming ΔSoHAT. Calorimetry on TEMPOH + tBu3PhO• gives ΔHoHAT = −11.2 ± 0.5 kcal mol−1 which matches the enthalpy predicted from the difference in literature solution BDEs. A brief evaluation of the literature thermochemistry of TEMPOH and tBu3PhOH supports the common assumption that ΔSoHAT ≈ 0 for HAT reactions of organic and small gas-phase molecules. However, this assumption does not hold for transition metal based HAT reactions. The trend in magnitude of |ΔSoHAT| for reactions with TEMPO, RuII(acac)2(py-imH) << [FeII(H2bip)3]2+ = [FeII(H2bim)3]2+ < [CoII(H2bim)3]2+, is surprisingly well predicted by the trends for electron transfer half-reaction entropies, ΔSoET, in aprotic solvents. This is because both ΔSoET and ΔSoHAT have substantial contributions from vibrational entropy, which varies significantly with the metal center involved. The close connection between ΔSoHAT and ΔSoET provides an important

Trauma potential and ballistic parameters of cal. 9 mm P.A. dummy launchers.

PubMed

Frank, Matthias; Bockholdt, Britta; Philipp, Klaus-Peter; Ekkernkamp, Axel

2010-07-15

Blank cartridge actuated dummy launching devices are used by migratory bird hunters to train dogs to retrieve downed birds. The devices create a loud noise while simultaneously propelling a hard foam dummy for retrieval. A newly developed dummy launcher is based on a modified cal. 9 mm P.A. blank handgun with an extension tube pinned and welded to the barrel imitation. Currently, there are no experimental investigations on the ballistic background and trauma potential of these uncommon shooting devices. An experimental test set-up consisting of a photoelectric infrared light barrier was used for measurement of the velocity of hard foam dummies propelled with an automatic dummy launcher. Ballistic parameters of the dummies and an aluminium sleeve as improvised projectile (kinetic energy (E), impulse (p), energy density (E') and threshold velocity (v(tsh)) to cause penetrating wounds as a function of cross-sectional density (S)) were calculated. The average velocity (v) of the dummies was measured 25.71 m/s exerting an average impulse (p) of 3.342 Ns. The average kinetic energy (E) was calculated 43.04 J with an average energy density (E') of 0.069 J/mm(2). The average velocity (v) of the aluminium sleeves as improvised projectiles was measured 79.58 m/s exerting an average impulse (p) of 2.228 Ns. The average kinetic energy (E) of the aluminium sleeves was calculated as 88.70 J with an average energy density (E') of 0.282 J/mm(2). The energy delivered by these shooting devices is high enough to cause relevant injuries. The absence of skin penetration must not mislead the emergency physician or forensic expert into neglecting the potential damage from these devices. (c) 2010 Elsevier Ireland Ltd. All rights reserved.

How do skeletons with HIV present? A study on the identified CAL Milano Cemetery Skeletal Collection.

PubMed

Biehler-Gomez, Lucie; Cabrini, Antonio; De Angelis, Danilo; Cattaneo, Cristina

2018-04-24

With the Human Immunodeficiency Virus (HIV) infection and Acquired Immune Deficiency Syndrome (AIDS) pandemic, the study of HIV/AIDS on bones has become of pivotal interest for research in bone pathologies, forensic applications (especially in the matter of identification when confronted to antemortem data) and medical purposes. In this paper, we document and discuss the macroscopic lesions found on the skeletons of nine individuals with known HIV, including four with known AIDS, coming from the identified CAL Milano Cemetery Skeletal Collection. As a result, several types of lesions were observed on bones: periosteal new bone formation, dental lesions, thickening of the frontal diploë, destructive localized porosity and evidence of trauma. None of the lesions reported can be directly linked to HIV because the virus does not directly affect bones in a macroscopic way. However, HIV/AIDS-induced infections and inflammations and HIV-related risk factors may leave bone markers. The differential diagnosis of each of the lesions noted in this research and its potential link to HIV or AIDS was discussed. Although it is not possible to diagnose HIV on bare bones, this was not the focus of this study. To our knowledge, no anthropological study has ever been performed on known HIV individuals. With this paper, we present for the first time skeletons with known HIV. Copyright © 2018 Elsevier B.V. All rights reserved.

Ecological response to climate change and human activities indicated by n-alkane proxy during the mid- to late Holocene: a case study from an alpine lake

NASA Astrophysics Data System (ADS)

Zhang, C.; Zhao, C.

2017-12-01

Paleolimonological records provide long-term dynamics information of past climate, environment, human activities and ecological variations and give evolutionary perspectives to understand responses process of ecological shift to internal or external trigger. In this study, a powerful biomarkers, n-alkanes, was used to reconstruct the past 5000 years organic matter sources and ecological evolution history of Beilianchi Lake in the southwestern of Loess Plateau after preliminary investigation of modern samples. Climate-environment change and human activities were also traced by total organic matter (TOC), magnetic susceptibility (MS) and relevant proxies. The results showed that the ecosystem related to organic matter composition in Beilianchi Lake might be mainly controlled by climate change before 1400 cal B.P., whereas after that, it was significantly influenced by soil erosion induced by increasing population and enhanced human activities. Lake ecosystem experienced periodical change from relatively stable stage with combination of allochthonous-autochthonous organic sources prior to 1400 cal B.P. to extremely instability and final return to steady state with allochthonous-dominant organic source since 300 cal B.P.. During the period of instability, organic matter composition during 1400-800 cal B.P. indicated a obvious bimodal distribution based on probability density distribution analysis, which reflected the lake ecosystem might stay at bistable state and switched repeatedly from more-macrophytes state (regime A with low ACL) towards less-macrophytes state (regime B with high ACL) controlled by disturbance of soil erosion. The flickering during this period could serve as the early warning signal of transition towards more-macrophytes state or less-macrophytes state in lake ecosystems.

State Medicaid abortion policies continue to be challenged; courts reach varying conclusions.

PubMed

1979-08-01

There is no consensus by the courts on what states may or may not legally do with regard to Medicaid funding of abortion. In Georgia a federal judge ruled that the state may not limit coverage of Medicaid abortions to those reimbursable by the federal government under the Hyde Amendment. In California funding of Medi-Cal abortions is permitted only if the woman's life is endangered; pregnancy is ectopic; the woman was raped; a minor under age 16; a victim of incest; the fetus is abnormal; or woman will suffer physical health damage. In Michigan Government William G. Milliken vetoed an appropriation of $1 for therapeutic abortion attached to a bill for hospital, physicians, and pharmacological services. Circuit Judge Jack W. Warren held that the governor did not have the authority to veto just one portion of the appropriation but must veto the entire bill. A New Jersey superior court judge has held unconstitutional proposed state guidelines which restricted Medicaid funding of abortions to those situations covered by the Hyde Amendment. A Hawaii circuit court has ruled that the state Department of Social Services and Housing has the authority to use state funds to pay for elective abortions for Medicaid recipients.

Using FORSEE and continuous forest inventory information to evaluate implementation of uneven-aged management in Santa Cruz County coast redwood forests

Treesearch

Douglas D. Piirto; Scott Sink; Dominic Ali; Steve Auten; Christopher Hipkin; Reid. Cody

2012-01-01

Swanton Pacific Ranch in northern Santa Cruz County has been owned and managed by California Polytechnic State University (Cal Poly) Foundation since 1987. The California Forest Practice Rules specific to Santa Cruz County limit harvest rate and opening size. Cal Poly forest managers are implementing uneven-aged forest management on 1,182 acres of 80 to 110...

Maximum caliber inference of nonequilibrium processes

NASA Astrophysics Data System (ADS)

Otten, Moritz; Stock, Gerhard

2010-07-01

Thirty years ago, Jaynes suggested a general theoretical approach to nonequilibrium statistical mechanics, called maximum caliber (MaxCal) [Annu. Rev. Phys. Chem. 31, 579 (1980)]. MaxCal is a variational principle for dynamics in the same spirit that maximum entropy is a variational principle for equilibrium statistical mechanics. Motivated by the success of maximum entropy inference methods for equilibrium problems, in this work the MaxCal formulation is applied to the inference of nonequilibrium processes. That is, given some time-dependent observables of a dynamical process, one constructs a model that reproduces these input data and moreover, predicts the underlying dynamics of the system. For example, the observables could be some time-resolved measurements of the folding of a protein, which are described by a few-state model of the free energy landscape of the system. MaxCal then calculates the probabilities of an ensemble of trajectories such that on average the data are reproduced. From this probability distribution, any dynamical quantity of the system can be calculated, including population probabilities, fluxes, or waiting time distributions. After briefly reviewing the formalism, the practical numerical implementation of MaxCal in the case of an inference problem is discussed. Adopting various few-state models of increasing complexity, it is demonstrated that the MaxCal principle indeed works as a practical method of inference: The scheme is fairly robust and yields correct results as long as the input data are sufficient. As the method is unbiased and general, it can deal with any kind of time dependency such as oscillatory transients and multitime decays.

Welcome to the California State Web Portal

Science.gov Websites

information. Update Location Clear Location × Default High Contrast Reset Increase Font SizeFont Decrease with High Speed Rail? are California's climate change goals? are my business opportunities in Department of Resources Recycling and Recovery (CalRecycle) Find out where to recycle beverage containers

California's Methane Budget derived from CalNex P-3 Aircraft Observations and the WRF-STILT Lagrangian Transport Model

NASA Astrophysics Data System (ADS)

Santoni, G. W.; Xiang, B.; Kort, E. A.; Daube, B.; Andrews, A. E.; Sweeney, C.; Wecht, K.; Peischl, J.; Ryerson, T. B.; Angevine, W. M.; Trainer, M.; Nehrkorn, T.; Eluszkiewicz, J.; Wofsy, S. C.

2012-12-01

We present constraints on California emission inventories of methane (CH4) using atmospheric observations from nine NOAA P-3 flights during the California Nexus (CalNex) campaign in May and June of 2010. Measurements were made using a quantum cascade laser spectrometer (QCLS) and a cavity ring-down spectrometer (CRDS) and calibrated to NOAA standards in-flight. Five flights sampled above the northern and southern central valley and an additional four flights probed the south coast air basin, quantifying emissions from the Los Angeles basin. The data show large (>100 ppb) CH4 enhancements associated with point and area sources such as cattle and manure management, landfills, wastewater treatment, gas production and distribution infrastructure, and rice agriculture. We compare aircraft observations to modeled CH4 distributions by accounting for a) transport using the Stochastic Time-Inverted Lagrangian Transport (STILT) model driven by Weather Research and Forecasting (WRF) meteorology, b) emissions from inventories such as EDGAR and ones constructed from California-specific state and county databases, each gridded to 0.1° x 0.1° resolution, and c) spatially and temporally evolving boundary conditions such as GEOS-Chem and a NOAA aircraft profile measurement derived curtain imposed at the edge of the WRF domain. After accounting for errors associated with transport, planetary boundary layer height, lateral boundary conditions, seasonality of emissions, and the spatial resolution of surface emission prior estimates, we find that the California Air Resources Board (CARB) CH4 budget is a factor of 1.64 too low. Using a Bayesian inversion to the flight data, we estimate California's CH4 budget to be 2.5 TgCH4/yr, with emissions from cattle and manure management, landfills, rice, and natural gas infrastructure, representing roughly 82%, 26%, 9% and 32% (sum = 149% with other sources accounting for the additional 15%) of the current CARB CH4 budget estimate of 1.52 TgCH4

Nitrous Oxide (N2O) Emissions from California based on 2010 CalNex Airborne Measurements

NASA Astrophysics Data System (ADS)

Xiang, B.; Miller, S.; Kort, E. A.; Santoni, G. W.; Daube, B.; Commane, R.; Angevine, W. M.; Ryerson, T. B.; Trainer, M.; Andrews, A. E.; Nehrkorn, T.; Tian, H.; Wofsy, S. C.

2012-12-01

Nitrous oxide (N2O) is an important gas for climate and for stratospheric chemistry, with an atmospheric lifetime exceeding 100 years. Global concentrations have increased steadily since the 18th century, apparently due to human-associated emissions, principally from application of nitrogen fertilizers. However, quantitative studies of agricultural emissions at large spatial scales are lacking, inhibited by the difficulty of measuring small enhancements of atmospheric concentrations. Here we derive regional emission rates for N2O in the Central Valley of California, based on analysis of in-situ airborne atmospheric observations collected using a quantum cascade laser spectrometer. The data were obtained on board the NOAA P-3 research aircraft during the CalNex (California Research at the Nexus of Air Quality and Climate Change) program in May and June, 2010. We coupled WRF (Weather Research and Forecasting) model to STILT (Stochastic Time-Inverted Lagrangian Transport) to link our in-situ observations to surface emissions, and then used a variety of statistical methods to identify source areas and to extract optimized emission rates from the inversion. Our results support the view that fertilizer application is the largest source of N2O in the Central Valley. But the spatial distribution of derived surface emissions, based on California land use and activity maps, was very different than indicated in the leading emissions inventory (EDGAR 4.0), and our estimated total emission flux of N2O for California during the study period was 3 - 4 times larger than EDGAR and other inventories.

Measurements of hydroxyl and hydroperoxy radicals during CalNex-LA: Model comparisons and radical budgets

NASA Astrophysics Data System (ADS)

Griffith, S. M.; Hansen, R. F.; Dusanter, S.; Michoud, V.; Gilman, J. B.; Kuster, W. C.; Veres, P. R.; Graus, M.; de Gouw, J. A.; Roberts, J.; Young, C.; Washenfelder, R.; Brown, S. S.; Thalman, R.; Waxman, E.; Volkamer, R.; Tsai, C.; Stutz, J.; Flynn, J. H.; Grossberg, N.; Lefer, B.; Alvarez, S. L.; Rappenglueck, B.; Mielke, L. H.; Osthoff, H. D.; Stevens, P. S.

2016-04-01

Measurements of hydroxyl (OH) and hydroperoxy (HO2*) radical concentrations were made at the Pasadena ground site during the CalNex-LA 2010 campaign using the laser-induced fluorescence-fluorescence assay by gas expansion technique. The measured concentrations of OH and HO2* exhibited a distinct weekend effect, with higher radical concentrations observed on the weekends corresponding to lower levels of nitrogen oxides (NOx). The radical measurements were compared to results from a zero-dimensional model using the Regional Atmospheric Chemical Mechanism-2 constrained by NOx and other measured trace gases. The chemical model overpredicted measured OH concentrations during the weekends by a factor of approximately 1.4 ± 0.3 (1σ), but the agreement was better during the weekdays (ratio of 1.0 ± 0.2). Model predicted HO2* concentrations underpredicted by a factor of 1.3 ± 0.2 on the weekends, while measured weekday concentrations were underpredicted by a factor of 3.0 ± 0.5. However, increasing the modeled OH reactivity to match the measured total OH reactivity improved the overall agreement for both OH and HO2* on all days. A radical budget analysis suggests that photolysis of carbonyls and formaldehyde together accounted for approximately 40% of radical initiation with photolysis of nitrous acid accounting for 30% at the measurement height and ozone photolysis contributing less than 20%. An analysis of the ozone production sensitivity reveals that during the week, ozone production was limited by volatile organic compounds throughout the day during the campaign but NOx limited during the afternoon on the weekends.

Volatile organic compounds in Tijuana during the Cal-Mex 2010 campaign: Measurements and source apportionment

NASA Astrophysics Data System (ADS)

Zheng, Jun; Garzón, Jessica P.; Huertas, María E.; Zhang, Renyi; Levy, Misti; Ma, Yan; Huertas, José I.; Jardón, Ricardo T.; Ruíz, Luis G.; Tan, Haobo; Molina, Luisa T.

2013-05-01

As part of the Cal-Mex 2010 air quality study, a proton transfer reaction-mass spectrometer (PTR-MS) was deployed at the San Diego-Tijuana border area to measure volatile organic compounds (VOCs) from 15 May to 30 June 2010. The major VOCs identified during the study included oxygenated VOCs (e.g., methanol, acetaldehyde, acetone, and methyl ethyl ketone) and aromatics (e.g., benzene, toluene, C8- and C9-aromatics). Biogenic VOCs (e.g., isoprene) were scarce in this region because of the lack of vegetation in this arid area. Using an U.S. EPA positive matrix factorization model, VOCs together with other trace gases (NOx, NOz and SO2) observed in this border region were attributed to four types of sources, i.e., local industrial solvent usage (58% in ppbC), gasoline vehicle exhaust (19% in ppbC), diesel vehicle exhaust (14% in ppbC), and aged plume (9% in ppbC) due to regional background and/or long-range transport. Diesel vehicle emission contributed to 87% of SO2 and 75% of NOx, and aged plume contributed to 92% of NOz. An independent conditional probability function analysis of VOCs, wind direction, and wind speed indicated that the industrial source did not show a significant tendency with wind direction. Both gasoline and diesel engine emissions were associated with air masses passing through two busy cross-border ports. Aged plumes were strongly associated with NW wind, which likely brought in aged air masses from the populated San Diego area.

Surface Irregularity Factor as a Parameter to Evaluate the Fatigue Damage State of CFRP

PubMed Central

Zuluaga-Ramírez, Pablo; Frövel, Malte; Belenguer, Tomás; Salazar, Félix

2015-01-01

This work presents an optical non-contact technique to evaluate the fatigue damage state of CFRP structures measuring the irregularity factor of the surface. This factor includes information about surface topology and can be measured easily on field, by techniques such as optical perfilometers. The surface irregularity factor has been correlated with stiffness degradation, which is a well-accepted parameter for the evaluation of the fatigue damage state of composite materials. Constant amplitude fatigue loads (CAL) and realistic variable amplitude loads (VAL), representative of real in- flight conditions, have been applied to “dog bone” shaped tensile specimens. It has been shown that the measurement of the surface irregularity parameters can be applied to evaluate the damage state of a structure, and that it is independent of the type of fatigue load that has caused the damage. As a result, this measurement technique is applicable for a wide range of inspections of composite material structures, from pressurized tanks with constant amplitude loads, to variable amplitude loaded aeronautical structures such as wings and empennages, up to automotive and other industrial applications. PMID:28793655

Transformation of Army National Guard Environmental Performance Assessment System (EPAS): Technologies and Best Practices in Field Audit Automation

DTIC Science & Technology

2012-05-01

Lorenzo Richmond San Francisco San Mateo Sunnyvale Salinas Oakdale Reedley Hanford Visalia Fresno Modesto Stockton Indio Burbank Orange Fullerton Glendale...Riverside El Centro Camp Morena National City San Diego Barstow Ontario Bakersfield Apple Valley Los Angeles Santa Barbara Santa Maria Camp San Luis

77 FR 56180 - Certain Frozen Fish Fillets From the Socialist Republic of Vietnam: Preliminary Results of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... Agriculture Marketing, Ministry of Agriculture, online pangas price data (``online DAM data'') on the record..., Department of Agricultural Marketing from Scot T. Fullerton, Program Manager, Questions for the Bangladeshi Department of Agricultural Marketing Regarding National Wholesale Price Data, '' dated July 27, 2012. \\42...

Examining the Relationship between College Football Season Ticket Holders' Service Personal Values and Their Behavioral Intentions: The Moderating Effect of Team Identification

ERIC Educational Resources Information Center

Tan, Gary Peng-Liang

2011-01-01

Recently, some college football programs have experienced unsustainable attendance growth, increases in revenue discrepancies, stagnant "revenue growth", and increased operating costs (Brown, 2009; Fulks, 2009; Fullerton & Morgan, 2009; Jackson, 2005; NCAA, 2009, 2010). These problems can be examined from customer service, social…

Heat Transfer Analysis of an Optimized, Flexible Holder System for Freeze-Drying in Dual Chamber Cartridges Using Different State-of-the-Art PAT Tools.

PubMed

Korpus, Christoph; Pikal, Michael; Friess, Wolfgang

2016-11-01

The aim of this study was to determine the heat transfer characteristics of an optimized flexible holder device, using Tunable Diode Laser Absorption Spectroscopy, the Pressure Rise Test, and the gravimetric procedure. Two different controlled nucleation methods were tested, and an improved sublimation process, "preheated plate," was developed. Tunable Diode Laser Absorption Spectroscopy identified an initial sublimation burst phase. Accordingly, steady-state equations were adapted for the gravimetric procedure, to account for this initial non-steady-state period. The heat transfer coefficient, K DCC , describing the transfer from the holder to the DCC, was the only heat transfer coefficient showing a clear pressure dependence with values ranging from 3.81E-04 cal/(g·cm 2 ·K) at 40 mTorr to 7.38E-04 cal/(g·cm 2 ·K) at 200 mTorr. The heat transfer coefficient, K tot , reflecting the overall energy transfer via the holder, increased by around 24% from 40 to 200 mTorr. This resulted in a pressure-independent sublimation rate of around 42 ± 1.06 mg/h over the whole pressure range. Hence, this pressure-dependent increase in energy transfer completely compensated the decrease in driving force of sublimation. The "flexible holder" shows a substantially reduced impact of atypical radiation, improved drying homogeneity, and ultimately a better transferability of the freeze-drying cycle for process optimization. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Precision and Accuracy of Intercontinental Distance Determinations Using Radio Interferometry.

DTIC Science & Technology

1983-07-01

applicsible) Air Forcc Gc.’!physics Laborator - LWG F19628-82-K- 0002 Sc ADDRESS ICity,. State and ZIP Code) 10. SOURCE OF FUNDING NOS. [lanscon AFB, MA...error in the calibration phase, E. Hence E tan-’[( Acsin, s- Acoso )/A ] (3.2.5)4s obs s obs cal and the corrected calibration phase will be given by cal m

Sustainability analysis using FORSEE and continuous forest inventory information to compare volume estimation methods for the Valencia coast redwood tract in Santa Cruz County, California

Treesearch

Douglas D. Piirto; Mitchell Haydon; Steve Auten; Benjamin Han; Samantha Gill; Wally Mark; Dale Holderman

2017-01-01

The 1,295 ha (3,200 ac) Swanton Pacific Ranch (Swanton) and the associated Valencia Tract in Santa Cruz County have been managed by California Polytechnic State University, San Luis Obispo (Cal Poly) since 1987. Swanton’s Valencia Tract is a 239 ha (591 ac) property located north of Watsonville, California. Cal Poly forest managers have conducted two harvest...

Evaluating ammonia (NH3) predictions in the NOAA National Air Quality Forecast Capability (NAQFC) using in-situ aircraft and satellite measurements from the CalNex2010 campaign

NASA Astrophysics Data System (ADS)

Bray, Casey D.; Battye, William; Aneja, Viney P.; Tong, Daniel; Lee, Pius; Tang, Youhua; Nowak, John B.

2017-08-01

Atmospheric ammonia (NH3) is not only a major precursor gas for fine particulate matter (PM2.5), but it also negatively impacts the environment through eutrophication and acidification. As the need for agriculture, the largest contributing source of NH3, increases, NH3 emissions will also increase. Therefore, it is crucial to accurately predict ammonia concentrations. The objective of this study is to determine how well the U.S. National Oceanic and Atmospheric Administration (NOAA) National Air Quality Forecast Capability (NAQFC) system predicts ammonia concentrations using their Community Multiscale Air Quality (CMAQ) model (v4.6). Model predictions of atmospheric ammonia are compared against measurements taken during the NOAA California Nexus (CalNex) field campaign that took place between May and July of 2010. Additionally, the model predictions were also compared against ammonia measurements obtained from the Tropospheric Emission Spectrometer (TES) on the Aura satellite. The results of this study showed that the CMAQ model tended to under predict concentrations of NH3. When comparing the CMAQ model with the CalNex measurements, the model under predicted NH3 by a factor of 2.4 (NMB = -58%). However, the ratio of the median measured NH3 concentration to the median of the modeled NH3 concentration was 0.8. When compared with the TES measurements, the model under predicted concentrations of NH3 by a factor of 4.5 (NMB = -77%), with a ratio of the median retrieved NH3 concentration to the median of the modeled NH3 concentration of 3.1. Because the model was the least accurate over agricultural regions, it is likely that the major source of error lies within the agricultural emissions in the National Emissions Inventory. In addition to this, the lack of the use of bidirectional exchange of NH3 in the model could also contribute to the observed bias.

Sedimentologic and Stratigraphic Aspects of Late Quaternary (<14 cal. ka?) Valley Fill (Paleo-Roanoke River) Beneath the Barrier Islands of the Outer Banks, North Carolina, USA

NASA Astrophysics Data System (ADS)

Farrell, K. M.; Brooks, R. W.

2002-12-01

Provided here is a preliminary interpretation of the late Pleistocene (<14 cal. ka) facies succession that infilled the paleo-Roanoke River valley, and its transition into the overlying barrier island complex beneath the Outer Banks of North Carolina. Previous work (e.g. Riggs and others, 1992) reported that the Albemarle Embayment of eastern N.C. is underlain by a series of Pleistocene paleovalley complexes and provided hypotheses to test regarding valley distribution, sea level changes, and the ages of facies and sequences generated in response to coastal evolution. This report provides stratigraphic and sedimentologic criteria to support collaborative interpretations of eight cores acquired by a coastal geology cooperative research program on the Outer Banks to test these hypotheses. In cores OBX-02, 03, and 05, the late Quaternary (<14 cal. ka) fill is about 41 m thick. Here it erosionally overlies a bioturbated marine shelf deposit (OBX-2, 3, 5) that Wehmiller (personal communication) correlated (at OBX-05, depth -41 m) with the early/middle Pleistocene aminozone, AZ-4 (see Riggs and others, 1992). Above this, the late Quaternary fill (in cores OBX-02, 03, 05, 06) includes a succession of four facies units: 1) a basal sandy gravel (<6 m), 2) a dark gray complexly interbedded mud and gravel (<9 m), 3) bioturbated muddy sand (<15 m), and 4) an upward fining sand, with a basal gravel (<15 m). (Dimensional aspects of these units remain undefined until integration with GPR and seismic profiles). Six radiocarbon dates (from Thieler, personal communication) on samples from unit 2 (OBX-05: from -32.3, -33.6 and -35 m; OBX-02: from -27.7, -33.0, and -33.0 m) fall within the range 10 to 14 cal. ka. These were deposited during the Younger Dryas (Mallinson and others, Thieler, personal communications). Stratigraphic relations suggest that unit 1, although not dated, was deposited at the onset of this phase of global cooling. Unit 1, interpreted as fluvial thalweg and

Modeling the weekly cycle of NOx and CO emissions and their impacts on O3 in the Los Angeles-South Coast Air Basin during the CalNex 2010 field campaign

NASA Astrophysics Data System (ADS)

Kim, S.-W.; McDonald, B. C.; Baidar, S.; Brown, S. S.; Dube, B.; Ferrare, R. A.; Frost, G. J.; Harley, R. A.; Holloway, J. S.; Lee, H.-J.; McKeen, S. A.; Neuman, J. A.; Nowak, J. B.; Oetjen, H.; Ortega, I.; Pollack, I. B.; Roberts, J. M.; Ryerson, T. B.; Scarino, A. J.; Senff, C. J.; Thalman, R.; Trainer, M.; Volkamer, R.; Wagner, N.; Washenfelder, R. A.; Waxman, E.; Young, C. J.

2016-02-01

We developed a new nitrogen oxide (NOx) and carbon monoxide (CO) emission inventory for the Los Angeles-South Coast Air Basin (SoCAB) expanding the Fuel-based Inventory for motor-Vehicle Emissions and applied it in regional chemical transport modeling focused on the California Nexus of Air Quality and Climate Change (CalNex) 2010 field campaign. The weekday NOx emission over the SoCAB in 2010 is 620 t d-1, while the weekend emission is 410 t d-1. The NOx emission decrease on weekends is caused by reduced diesel truck activities. Weekday and weekend CO emissions over this region are similar: 2340 and 2180 t d-1, respectively. Previous studies reported large discrepancies between the airborne observations of NOx and CO mixing ratios and the model simulations for CalNex based on the available bottom-up emission inventories. Utilizing the newly developed emission inventory in this study, the simulated NOx and CO mixing ratios agree with the observations from the airborne and the ground-based in situ and remote sensing instruments during the field study. The simulations also reproduce the weekly cycles of these chemical species. Both the observations and the model simulations indicate that decreased NOx on weekends leads to enhanced photochemistry and increase of O3 and Ox (=O3 + NO2) in the basin. The emission inventory developed in this study can be extended to different years and other urban regions in the U.S. to study the long-term trends in O3 and its precursors with regional chemical transport models.

Observations of Convective Development from Repeat Pass Radiometry during CalWaters 2015: Outlook for the TEMPEST Mission

NASA Astrophysics Data System (ADS)

Brown, S. T.

2015-12-01

The Temporal Experiment for Storms and Tropical Systems (TEMPEST), which was recently selected as a NASA Earth Ventures technology demonstration mission, uses a constellation of five CubeSats flying in formation to provide observations of developing precipitation with a temporal resolution of 5 minutes. The observations are made using small mm-wave radiometers with frequencies ranging from 90 to 183 GHz which are sensitive to the integrated ice water path above the precipitation layer in the storm. This paper describes TEMPEST like observations that were made with the High Altitude MMIC Sounding Radiometer (HAMSR) on the ER-2 during CalWaters 2015. HAMSR is a mm-wave airborne radiometer with 25 channels in three bands; 50, 118 and 183 GHz. During the campaign, a small isolated area of convection was identified by the ER-2 pilot and 5 overpasses of the area were made with about 5 minutes between each pass. The HAMSR data reveal two convective cells, one which was diminishing and one which was developing. The mm-wave channels near the 183 GHz water vapor line clearly show the change in the vertical extent of the storm with time, a proxy for vertical velocity. These data demonstrate the potential for TEMPEST like observations from an orbital vantage point. This paper will provide an overview of the measurements, an analysis of the observations and offer perspectives for the TEMPEST mission.

Diverse rupture modes for surface-deforming upper plate earthquakes in the southern Puget Lowland of Washington State

USGS Publications Warehouse

Nelson, Alan R.; Personius, Stephen F.; Sherrod, Brian L.; Kelsey, Harvey M.; Johnson, Samuel Y.; Bradley, Lee-Ann; Wells, Ray E.

2014-01-01

Earthquake prehistory of the southern Puget Lowland, in the north-south compressive regime of the migrating Cascadia forearc, reflects diverse earthquake rupture modes with variable recurrence. Stratigraphy and Bayesian analyses of previously reported and new 14C ages in trenches and cores along backthrust scarps in the Seattle fault zone restrict a large earthquake to 1040–910 cal yr B.P. (2σ), an interval that includes the time of the M 7–7.5 Restoration Point earthquake. A newly identified surface-rupturing earthquake along the Waterman Point backthrust dates to 940–380 cal yr B.P., bringing the number of earthquakes in the Seattle fault zone in the past 3500 yr to 4 or 5. Whether scarps record earthquakes of moderate (M 5.5–6.0) or large (M 6.5–7.0) magnitude, backthrusts of the Seattle fault zone may slip during moderate to large earthquakes every few hundred years for periods of 1000–2000 yr, and then not slip for periods of at least several thousands of years. Four new fault scarp trenches in the Tacoma fault zone show evidence of late Holocene folding and faulting about the time of a large earthquake or earthquakes inferred from widespread coseismic subsidence ca. 1000 cal yr B.P.; 12 ages from 8 sites in the Tacoma fault zone limit the earthquakes to 1050–980 cal yr B.P. Evidence is too sparse to determine whether a large earthquake was closely predated or postdated by other earthquakes in the Tacoma basin, but the scarp of the Tacoma fault was formed by multiple earthquakes. In the northeast-striking Saddle Mountain deformation zone, along the western limit of the Seattle and Tacoma fault zones, analysis of previous ages limits earthquakes to 1200–310 cal yr B.P. The prehistory clarifies earthquake clustering in the central Puget Lowland, but cannot resolve potential structural links among the three Holocene fault zones.

Holocene multidecadal and multicentennial droughts affecting Northern California and Nevada

USGS Publications Warehouse

Benson, L.; Kashgarian, Michaele; Rye, R.; Lund, S.; Paillet, F.; Smoot, J.; Kester, C.; Mensing, S.; Meko, D.; Lindstrom, S.

2002-01-01

Continuous, high-resolution ??18O records from cored sediments of Pyramid Lake, Nevada, indicate that oscillations in the hydrologic balance occurred, on average, about every 150 years (yr) during the past 7630 calendar years (cal yr). The records are not stationary; during the past 2740 yr, drought durations ranged from 20 to 100 yr and intervals between droughts ranged from 80 to 230 yr. Comparison of tree-ring-based reconstructions of climate change for the past 1200 yr from the Sierra Nevada and the El alpais region of northwest New Mexico indicates that severe droughts associated with Anasazi withdrawal from Chaco Canyon at 820 cal yr BP (calendar years before present) and final abandonment of Chaco Canyon, Mesa Verde, and the Kayenta area at 650 cal yr BP may have impacted much of the western United States.During the middle Holocene (informally defined in this paper as extending from 8000 to 3000 cal yr BP), magnetic susceptibility values of sediments deposited in Pyramid Lake's deep basin were much larger than late-Holocene (3000-0 cal yr BP) values, indicating the presence of a shallow lake. In addition, the mean ?? 18O value of CaCO3 precipitated between 6500 and 3430 cal yr BP was 1.6??? less than the mean value of CaCO3 precipitated after 2740 cal yr BP. Numerical calculations indicate that the shift in the ??18O baseline probably resulted from a transition to a wetter (> 30%) and cooler (3-5??C) climate. The existence of a relatively dry and warm middle-Holocene climate in the Truckee River - Pyramid Lake system is generally consistent with archeological, sedimentological, chemical, physical, and biological records from various sites within the Great Basin of the western United States. Two high-resolution Holocene-climate records are now available from the Pyramid and Owens lake basins which suggest that the Holocene was characterized by five climatic intervals. TIC and ??18O records from Owens Lake indicate that the first interval in the early Holocene

Holocene multidecadal and multicentennial droughts affecting Northern California and Nevada

NASA Astrophysics Data System (ADS)

Benson, Larry; Kashgarian, Michaele; Rye, Robert; Lund, Steve; Paillet, Fred; Smoot, Joseph; Kester, Cynthia; Mensing, Scott; Meko, Dave; Lindström, Susan

2002-02-01

Continuous, high-resolution δ18O records from cored sediments of Pyramid Lake, Nevada, indicate that oscillations in the hydrologic balance occurred, on average, about every 150 years (yr) during the past 7630 calendar years (cal yr). The records are not stationary; during the past 2740 yr, drought durations ranged from 20 to 100 yr and intervals between droughts ranged from 80 to 230 yr. Comparison of tree-ring-based reconstructions of climate change for the past 1200 yr from the Sierra Nevada and the El Malpais region of northwest New Mexico indicates that severe droughts associated with Anasazi withdrawal from Chaco Canyon at 820 cal yr BP (calendar years before present) and final abandonment of Chaco Canyon, Mesa Verde, and the Kayenta area at 650 cal yr BP may have impacted much of the western United States.During the middle Holocene (informally defined in this paper as extending from 8000 to 3000 cal yr BP), magnetic susceptibility values of sediments deposited in Pyramid Lake's deep basin were much larger than late-Holocene (3000-0 cal yr BP) values, indicating the presence of a shallow lake. In addition, the mean δ18O value of CaCO 3 precipitated between 6500 and 3430 cal yr BP was 1.6‰ less than the mean value of CaCO 3 precipitated after 2740 cal yr BP. Numerical calculations indicate that the shift in the δ18O baseline probably resulted from a transition to a wetter (>30%) and cooler (3-5°C) climate. The existence of a relatively dry and warm middle-Holocene climate in the Truckee River-Pyramid Lake system is generally consistent with archeological, sedimentological, chemical, physical, and biological records from various sites within the Great Basin of the western United States. Two high-resolution Holocene-climate records are now available from the Pyramid and Owens lake basins which suggest that the Holocene was characterized by five climatic intervals. TIC and δ18O records from Owens Lake indicate that the first interval in the early Holocene

Modeling the formation and aging of secondary organic aerosols in Los Angeles during CalNex 2010

NASA Astrophysics Data System (ADS)

Hayes, P. L.; Carlton, A. G.; Baker, K. R.; Ahmadov, R.; Washenfelder, R. A.; Alvarez, S.; Rappenglück, B.; Gilman, J. B.; Kuster, W. C.; de Gouw, J. A.; Zotter, P.; Prévôt, A. S. H.; Szidat, S.; Kleindienst, T. E.; Offenberg, J. H.; Jimenez, J. L.

2014-12-01

Four different parameterizations for the formation and evolution of secondary organic aerosol (SOA) are evaluated using a 0-D box model representing the Los Angeles Metropolitan Region during the CalNex 2010 field campaign. We constrain the model predictions with measurements from several platforms and compare predictions with particle and gas-phase observations from the CalNex Pasadena ground site. That site provides a unique opportunity to study aerosol formation close to anthropogenic emission sources with limited recirculation. The model SOA formed only from the oxidation of VOCs (V-SOA) is insufficient to explain the observed SOA concentrations, even when using SOA parameterizations with multi-generation oxidation that produce much higher yields than have been observed in chamber experiments, or when increasing yields to their upper limit estimates accounting for recently reported losses of vapors to chamber walls. The Community Multiscale Air Quality (WRF-CMAQ) model (version 5.0.1) provides excellent predictions of secondary inorganic particle species but underestimates the observed SOA mass by a factor of 25 when an older VOC-only parameterization is used, which is consistent with many previous model-measurement comparisons for pre-2007 anthropogenic SOA modules in urban areas. Including SOA from primary semi-volatile and intermediate volatility organic compounds (P-S/IVOCs) following the parameterizations of Robinson et al. (2007), Grieshop et al. (2009), or Pye and Seinfeld (2010) improves model/measurement agreement for mass concentration. When comparing the three parameterizations, the Grieshop et al. (2009) parameterization more accurately reproduces both the SOA mass concentration and oxygen-to-carbon ratio inside the urban area. Our results strongly suggest that other precursors besides VOCs, such as P-S/IVOCs, are needed to explain the observed SOA concentrations in Pasadena. All the parameterizations over-predict urban SOA formation at long

Shaking up the dental safety-net: elimination of optional adult dental Medicaid benefits in California.

PubMed

Wides, Cynthia; Alam, Sonia Rab; Mertz, Elizabeth

2014-02-01

In July 2009, California eliminated funding for most adult non-emergency Medicaid dental benefits (Denti-Cal). This paper presents the findings from a qualitative assessment of the impacts of the Denti-Cal cuts on California's oral health safety-net. Interviews were conducted with dental safety-net providers throughout the state, including public health departments, community health centers, dental schools, Native American health clinics, and private providers, and were coded thematically using Atlas.ti. Safety-net providers reported decreased utilization by Denti-Cal-eligible adults, who now primarily seek emergency dental services, and reported shifting to focus on pediatric and privately-insured patients. Significant changes were reported in safety-net clinic finances, operations, and ability to refer. The impact of the Denti-Cal cuts has been distributed unevenly across the safety-net, with private providers and County Health Departments bearing the highest burden.

Low-visibility light-intensity laser-triggered release of entrapped calcein from 1,2-bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine liposomes is mediated through a type I photoactivation pathway

PubMed Central

Yavlovich, Amichai; Viard, Mathias; Gupta, Kshitij; Sine, Jessica; Vu, Mylinh; Blumenthal, Robert; Tata, Darrell B; Puri, Anu

2013-01-01

We recently reported on the physical characteristics of photo-triggerable liposomes containing dipalmitoylphosphatidylcholine (DPPC), and 1,2-bis (tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine (DC8,9PC) carrying a photo agent as their payload. When exposed to a low-intensity 514 nm wavelength (continuous-wave) laser light, these liposomes were observed to release entrapped calcein green (Cal-G; Ex/Em 490/517 nm) but not calcein blue (Cal-B; Ex/Em 360/460 nm). In this study, we have investigated the mechanism for the 514 nm laser-triggered release of the Cal-G payload using several scavengers that are known specifically to inhibit either type I or type II photoreaction pathways. Liposomes containing DPPC:DC8,9PC: distearoylphosphatidylethanolamine (DSPE)-polyethylene glycol (PEG)-2000 (86:10:04 mole ratio) were loaded either with fluorescent (calcein) or nonfluorescent (3H-inulin) aqueous markers. In addition, a non-photo-triggerable formulation (1-palmitoyl-2-oleoyl phosphatidylcholine [POPC]:DC8,9PC:DSPE-PEG2000) was also studied with the same payloads. The 514 nm wavelength laser exposure on photo-triggerable liposomes resulted in the release of Cal-G but not that of Cal-B or 3H-inulin, suggesting an involvement of a photoactivated state of Cal-G due to the 514 nm laser exposure. Upon 514 nm laser exposures, substantial hydrogen peroxide (H2O2, ≈100 μM) levels were detected from only the Cal-G loaded photo-triggerable liposomes but not from Cal-B-loaded liposomes (≤10 μM H2O2). The Cal-G release from photo-triggerable liposomes was found to be significantly inhibited by ascorbic acid (AA), resulting in a 70%–80% reduction in Cal-G release. The extent of AA-mediated inhibition of Cal-G release from the liposomes also correlated with the consumption of AA. No AA consumption was detected in the 514 nm laserexposed Cal B-loaded liposomes, thus confirming a role of photoactivation of Cal-G in liposome destabilization. Inclusion of 100 mM K3Fe(CN)6 (a

Enrolling in Medicaid through the National School Lunch Program: outcome of a pilot project in California schools.

PubMed

Cousineau, Michael R; Wada, Eriko O; Hogan, Laura

2007-01-01

California has several health insurance programs for children. However, the system for enrolling into these programs is complex and difficult to manage for many families. Express Lane Eligibility is designed to streamline the Medicaid (called Medi-Cal in California) enrollment process by linking it to the National School Lunch Program. If a child is eligible for free lunch and the parents consent, the program provides two months of presumptive eligibility for Medi-Cal and a simplified application process for continuation in Medi-Cal. For those who are ineligible, it provides a referral to other programs. An evaluation of Express Lane shows that while many children were presumptively enrolled, nearly half of the applicants were already enrolled in Medi-Cal. Many Express Enrolled children failed to complete the full Medi-Cal enrollment process. Few were referred to the State Children's Health Insurance Program or county programs. Express Lane is less useful as a broad screening strategy, but can be one of many tools that communities use to enroll children in health insurance.

Applying the Nominal Response Model within a Longitudinal Framework to Construct the Positive Family Relationships Scale

ERIC Educational Resources Information Center

Preston, Kathleen Suzanne Johnson; Parral, Skye N.; Gottfried, Allen W.; Oliver, Pamella H.; Gottfried, Adele Eskeles; Ibrahim, Sirena M.; Delany, Danielle

2015-01-01

A psychometric analysis was conducted using the nominal response model under the item response theory framework to construct the Positive Family Relationships scale. Using data from the Fullerton Longitudinal Study, this scale was constructed within a long-term longitudinal framework spanning middle childhood through adolescence. Items tapping…

STS-51F crew activities

NASA Image and Video Library

2009-06-25

51F-06-017 (29 July-6 Aug. 1985) --- Crew portrait with sunglasses. C. Gordon Fullerton's head is at center. Others (bottom, l.-r.) are Roy D. Bridges, F. Story Musgrave and John David Bartoe; and (top) Karl J. Henize, Loren W. Acton and Anthony W. England.

Development of SMAP Mission Cal/Val Activities

NASA Technical Reports Server (NTRS)

Colliander, A.; Jackson, T.; Kimball, J.; Cosh, M.; Spencer, M.; Entekhabi, D.; Njoku, E.; ONeill, P.

2010-01-01

The Soil Moisture Active Passive (SMAP) mission is a NASA directed mission to map global land surface soil moisture and freeze-thaw state. Instrument and mission details are shown. The key SMAP soil moisture product is provided at 10 km resolution with 0.04cubic cm/cubic cm accuracy. The freeze/thaw product is provided at 3 km resolution and 80% frozen-thawed classification accuracy. The full list of SMAP data products is shown.

Commander Lousma works with EEVT experiment on aft middeck

NASA Image and Video Library

1982-03-31

S82-28911 (March 1982) --- The L-shaped experiment in the right half of this photo was one of a number of scientific experiments which made the trip for NASA's third space transportation system (STS-3) mission, along with astronauts Jack R. Lousma, pictured, and C. Gordon Fullerton. The experiment, making encore in space (it also flew on the Apollo Soyuz Test Project in 1985), is designed to evaluate the feasibility of separating cells according to their surface electrical charge. It is a forerunner to planned experiments with other equipment that will purify biological materials in the low gravity environment of space. The process of electrophoresis utilizes an electric field to separate cells, and other biological material in fluids without damaging the cells which can then be used in the study of cell biology, immunology and medical research. This photograph was taken with a 35mm camera by Fullerton. Photo credit: NASA

Developing Talents: A Longitudinal Examination of Intellectual Ability and Academic Achievement

ERIC Educational Resources Information Center

McCoach, D. Betsy; Yu, Huihui; Gottfried, Allen W.; Gottfried, Adele Eskeles

2017-01-01

The Fullerton Longitudinal Study offers a unique opportunity to model the stability of intelligence and achievement and their relations from elementary through secondary school. Using latent variable modeling, we fit a cross-lagged panel model to examine the relations between intelligence and achievement in two academic domains: mathematics and…

Distance traveled for Medicaid-covered abortion care in California.

PubMed

Johns, Nicole E; Foster, Diana Greene; Upadhyay, Ushma D

2017-04-19

Access to abortion care in the United States is limited by the availability of abortion providers and their geographic distribution. We aimed to assess how far women travel for Medicaid-funded abortion in California and identify disparities in access to abortion care. We obtained data on all abortions reimbursed by the fee-for-service California state Medicaid program (Medi-Cal) in 2011 and 2012 and examined distance traveled to obtain abortion care by several demographic and abortion-related factors. Mixed-effects multivariable logistic regression models were constructed to examine factors associated with traveling 50 miles or more. County-level t-tests and linear regressions were conducted to examine the effects of a Medi-Cal abortion provider in a county on overall and urban/rural differences in utilization. 11.9% (95% CI: 11.5-12.2%) of women traveled 50 miles or more. Women obtaining second trimester or later abortions (21.7%), women obtaining abortions at hospitals (19.9%), and rural women (51.0%) were most likely to travel 50 miles or more. Across the state, 28 counties, home to 10% of eligible women, did not have a facility routinely providing Medi-Cal-covered abortions. Efforts are needed to expand the number of abortion providers that accept Medi-Cal. This could be accomplished by increasing Medi-Cal reimbursement rates, increasing the types of providers who can provide abortions, and expanding the use of telemedicine. If national trends in declining unintended pregnancy and abortion rates continue, careful attention should be paid to ensure that reduced demand does not lead to greater disparities in geographic and financial access to abortion care by ensuring that providers accepting Medicaid payment are available and widely distributed.

Supreme Court Upholds Cal. Law Requiring Maternity Leaves.

ERIC Educational Resources Information Center

Fields, Cheryl M.

1987-01-01

A recent United State Supreme Court ruling upheld a California law requiring employers to grant female employees up to four months of unpaid maternity leave and make reasonable efforts to reinstate them when they return to work. The decision and its implications are discussed. (MSE)

Benefit Analysis Report, United States Air Force Technical Order Management Systems (AFTOMS)

DOT National Transportation Integrated Search

1989-08-01

This report prepared by the Transportation Systems Center (TSC) concludes an analysis of the Technical Order (TO) costs and benefits, which was originally undertaken as part of the US Air Force Computer-aided Acquisition and Logistics Support (CALS) ...

Bayesian chronological analyses consistent with synchronous age of 12,835-12,735 Cal B.P. for Younger Dryas boundary on four continents

NASA Astrophysics Data System (ADS)

Kennett, James P.; Kennett, Douglas J.; Culleton, Brendan J.; Emili Aura Tortosa, J.; Bischoff, James L.; Bunch, Ted E.; Daniel, I. Randolph, Jr.; Erlandson, Jon M.; Ferraro, David; Firestone, Richard B.; Goodyear, Albert C.; Israde-Alcántara, Isabel; Johnson, John R.; Jordá Pardo, Jesús F.; Kimbel, David R.; LeCompte, Malcolm A.; Lopinot, Neal H.; Mahaney, William C.; Moore, Andrew M. T.; Moore, Christopher R.; Ray, Jack H.; Stafford, Thomas W., Jr.; Barnett Tankersley, Kenneth; Wittke, James H.; Wolbach, Wendy S.; West, Allen

2015-08-01

The Younger Dryas impact hypothesis posits that a cosmic impact across much of the Northern Hemisphere deposited the Younger Dryas boundary (YDB) layer, containing peak abundances in a variable assemblage of proxies, including magnetic and glassy impact-related spherules, high-temperature minerals and melt glass, nanodiamonds, carbon spherules, aciniform carbon, platinum, and osmium. Bayesian chronological modeling was applied to 354 dates from 23 stratigraphic sections in 12 countries on four continents to establish a modeled YDB age range for this event of 12,835-12,735 Cal B.P. at 95% probability. This range overlaps that of a peak in extraterrestrial platinum in the Greenland Ice Sheet and of the earliest age of the Younger Dryas climate episode in six proxy records, suggesting a causal connection between the YDB impact event and the Younger Dryas. Two statistical tests indicate that both modeled and unmodeled ages in the 30 records are consistent with synchronous deposition of the YDB layer within the limits of dating uncertainty (∼100 y). The widespread distribution of the YDB layer suggests that it may serve as a datum layer.

Bayesian chronological analyses consistent with synchronous age of 12,835-12,735 Cal B.P. for Younger Dryas boundary on four continents.

PubMed

Kennett, James P; Kennett, Douglas J; Culleton, Brendan J; Aura Tortosa, J Emili; Bischoff, James L; Bunch, Ted E; Daniel, I Randolph; Erlandson, Jon M; Ferraro, David; Firestone, Richard B; Goodyear, Albert C; Israde-Alcántara, Isabel; Johnson, John R; Jordá Pardo, Jesús F; Kimbel, David R; LeCompte, Malcolm A; Lopinot, Neal H; Mahaney, William C; Moore, Andrew M T; Moore, Christopher R; Ray, Jack H; Stafford, Thomas W; Tankersley, Kenneth Barnett; Wittke, James H; Wolbach, Wendy S; West, Allen

2015-08-11

The Younger Dryas impact hypothesis posits that a cosmic impact across much of the Northern Hemisphere deposited the Younger Dryas boundary (YDB) layer, containing peak abundances in a variable assemblage of proxies, including magnetic and glassy impact-related spherules, high-temperature minerals and melt glass, nanodiamonds, carbon spherules, aciniform carbon, platinum, and osmium. Bayesian chronological modeling was applied to 354 dates from 23 stratigraphic sections in 12 countries on four continents to establish a modeled YDB age range for this event of 12,835-12,735 Cal B.P. at 95% probability. This range overlaps that of a peak in extraterrestrial platinum in the Greenland Ice Sheet and of the earliest age of the Younger Dryas climate episode in six proxy records, suggesting a causal connection between the YDB impact event and the Younger Dryas. Two statistical tests indicate that both modeled and unmodeled ages in the 30 records are consistent with synchronous deposition of the YDB layer within the limits of dating uncertainty (∼ 100 y). The widespread distribution of the YDB layer suggests that it may serve as a datum layer.

Late-glacial and Holocene Vegetation and Climate Variability, Including Major Droughts, in the Sky Lakes Region of Southeastern New York State

NASA Technical Reports Server (NTRS)

Menking, Kirsten M.; Peteet, Dorothy M.; Anderson, Roger Y.

2012-01-01

Sediment cores from Lakes Minnewaska and Mohonk in the Shawangunk Mountains of southeastern New York were analyzed for pollen, plantmacrofossils, macroscopic charcoal, organic carbon content, carbon isotopic composition, carbon/nitrogen ratio, and lithologic changes to determine the vegetation and landscape history of the greater Catskill Mountain region since deglaciation. Pollen stratigraphy generally matches the New England pollen zones identified by Deevey (1939) and Davis (1969), with boreal genera (Picea, Abies) present during the late Pleistocene yielding to a mixed Pinus, Quercus and Tsuga forest in the early Holocene. Lake Minnewaska sediments record the Younger Dryas and possibly the 8.2 cal kyr BP climatic events in pollen and sediment chemistry along with an 1400 cal yr interval of wet conditions (increasing Tsuga and declining Quercus) centered about 6400 cal yr BP. BothMinnewaska andMohonk reveal a protracted drought interval in themiddle Holocene, 5700-4100 cal yr BP, during which Pinus rigida colonized the watershed, lake levels fell, and frequent fires led to enhanced hillslope erosion. Together, the records show at least three wet-dry cycles throughout the Holocene and both similarities and differences to climate records in New England and central New York. Drought intervals raise concerns for water resources in the New York City metropolitan area and may reflect a combination of enhanced La Niña, negative phase NAO, and positive phase PNA climatic patterns and/or northward shifts of storm tracks.

Postsecondary Play: The Role of Games and Social Media in Higher Education. Tech.edu: A Hopkins Series on Education and Technology

ERIC Educational Resources Information Center

Tierney, William G., Ed.; Corwin, Zoë B., Ed.; Fullerton, Tracy, Ed.; Ragusa, Gisele, Ed.

2017-01-01

The college application process--which entails multiple forms, essays, test scores, and deadlines--can be intimidating. For students without substantial school and family support, the complexity of this process can become a barrier to access. William G. Tierney, Tracy Fullerton, and their teams at the University of Southern California approach…

Sixteen Textbook Authors Respond.

ERIC Educational Resources Information Center

Hewitt, John P.; And Others

1988-01-01

The articles on textbook publication written by Sheryl Fullerton and Franklin C. Graham were responded to by: John Hewitt, Henry Tischler, George Ritzer, Paul Baker, Erich Goode, D. Stanley Eitzen, Jon Shepard, Richard Schaefer, Caroline Persell, Beth Hess, Paul Zopf, Jr., Jeanne Ballantine, Duane Monette, Mary Ann Lamanna, John Macionis, and…

Higher Functioning Adolescents and Young Adults with Autism: A Teacher's Guide.

ERIC Educational Resources Information Center

Fullerton, Ann; And Others

This guide offers strategies for working with students with autism in the areas of academic instruction, organization and time management, and social skills. The importance of considering the autistic student's use of language and thinking style is stressed. Chapter 1, "Who Are Higher Functioning Young Adults with Autism?" (Ann Fullerton),…

"Putting Ourselves in Their Shoes": Case Studies of Four Teenagers' Reading Experiences with Nonfiction Literature in a Social Studies Classroom

ERIC Educational Resources Information Center

Beach, Shannon L.

2012-01-01

The purpose of this qualitative study was to examine student experiences reading nonfiction literature in a social studies classroom. It examined the transactions that took place between the readers and the nonfiction literature in a social studies setting at Fullerton High School, a suburban school in Northeast, Ohio. Reader responses, including…

Materials research for passive solar systems: Solid-state phase-change materials

NASA Astrophysics Data System (ADS)

Benson, D. K.; Webb, J. D.; Burrows, R. W.; McFadden, J. D. O.; Christensen, C.

1985-03-01

A set of solid-state phase-change materials is being evaluated for possible use in passive solar thermal energy storage systems. The most promising materials are organic solid solutions of pentaerythritol (C5H12O4), pentaglycerinve (C5H12O3), and neopentyl glycol (C5H12O2). Solid solution mixtures of these compounds can be tailored so that they exhibit solid-to-solid phase transformations at any desired temperature between 25 C and 188 C, and have latent heats of transformation etween 20 and 70 cal/g. Transformation temperatures, specific heats, and latent heats of transformation have been measured for a number of these materials. Limited cyclic experiments suggest that the solid solutions are stable. These phase-change materials exhibit large amounts of undercooling; however, the addition of certain nucleating agents as particulate dispersions in the solid phase-change material greatly reduces this effect. Computer simulations suggest that the use of an optimized solid-state phase-change material in a Trombe wall could provide better performance than a concrete Trombe wall four times thicker and nine times heavier.

Ozone formation along the California-Mexican border region during Cal-Mex 2010 field campaign

NASA Astrophysics Data System (ADS)

Li, Guohui; Bei, Naifang; Zavala, Miguel; Molina, Luisa T.

2014-05-01

The purpose of this study is to evaluate the ozone (O3) formation along the California-Mexico border region using the WRF-CHEM model in association with the Cal-Mex 2010 field campaign. Four two-day episodes in 2010 are chosen based on plume transport patterns: 1) May 15-16 (plume north), 2) May 29-30 (plume southwest), 3) June 4-5 (plume east), and 4) June 13-14 (plume southeast). Generally, the predicted O3 spatial patterns and temporal variations agree well with the observations at the ambient monitoring sites in the San Diego-Tijuana region, but in the Calexico-Mexicali region, the model frequently underestimates the observation. In the San Diego-Tijuana region, the morning anthropogenic precursor emissions in the urbanized coastal plain are carried inland and mixed with the local biogenic emissions during transport, causing the high O3 level over the mountain region. Biogenic emissions enhance the O3 concentrations by up to 40 ppb over the mountain region in the afternoon. The factor separation approach is used to evaluate the contributions of trans-boundary transport of emissions from California and Baja California to the O3 level in the California-Mexico border region. The Baja California emissions play a minor role in the O3 formation in the San Diego region and do not seem to contribute to the O3 exceedances in the region, but have large potential to cause O3 exceedances in the Calexico region. The California emissions can considerably enhance the O3 level in the Tijuana region. Generally, the California emissions play a more important role than the Baja California emissions on O3 formation in the border region (within 40 km to the California-Mexico border). On average, the O3 concentrations in the border region are decreased by 2-4 ppb in the afternoon due to the interactions of emissions from California and Baja California. Further studies need to be conducted to improve the sea breeze simulations in the border region for evaluating O3 formation.

Rapid Prototyping of Application Specific Signal Processors Program

DTIC Science & Technology

1992-10-09

EREQ Query optimizer generator from the University of Colorado. In the five year time frame , this trend toward convergence makes it a non- issue ...related issues . TI’s RASSP vision plans to leverage and support CALS as a baseline for addressing data formatting and handling. Previously stated CALS goals ...of the U.S. Gc;:zrnrenL Distibution Statement A. Approved for public release; distribution is unlimited. Prepared By: _-- Texas Instruments Integrated

Evaluation of different methods for immobilization of Candida antarctica lipase B (CalB lipase) in polyurethane foam and its application in the production of geranyl propionate.

PubMed

Nicoletti, Gabrieli; Cipolatti, Eliane P; Valério, Alexsandra; Carbonera, NatáliaThaisa Gamba; Soares, Nicole Spillere; Theilacker, Eron; Ninow, Jorge L; de Oliveira, Débora

2015-09-01

With the aim of studying the best method for the interaction of polyurethane (PU) foam and Candida antarctica lipase B, different methods of CalB immobilization were studied: adsorption (PU-ADS), bond (using polyethyleneimine) (PU-PEI), ionic adsorption by PEI with cross-linking with glutaraldehyde (PU-PEI-GA) and entrapment (PU). The characterization of immobilized enzyme derivatives was performed by apparent density and Fourier transform infrared spectroscopy. The free enzyme and enzyme preparations were evaluated at different pH values and temperatures. The highest enzyme activity was obtained using the PU method (5.52 U/g). The methods that stood out to compare the stabilities and kinetic parameters were the PU and PU-ADS. Conversions of 83.5 and 95.9 % for PU and PU-ADS derivatives were obtained, in 24 h reaction, using citronella oil and propionic acid as substrates.

Adult Learners: Implications for Faculty.

ERIC Educational Resources Information Center

Kelly, Diana

Drawing from a review of the literature, this paper explores the role of university and community college faculty in teaching the growing number of adult students and potential adult students. First, section I offers background on the growth in adult enrollments at Fullerton College (California). Next, section II profiles the adult college…

A Latent Transition Analysis of Academic Intrinsic Motivation from Childhood through Adolescence

ERIC Educational Resources Information Center

Marcoulides, George A.; Gottfried, Adele Eskeles; Gottfried, Allen W.; Oliver, Pamella H.

2008-01-01

A longitudinal modeling approach was utilized to determine the existence of latent classes with regard to academic intrinsic motivation and the points of stability and transition of individuals between and within classes. A special type of latent Markov Chain model using "Mplus" was fit to data from the Fullerton Longitudinal Study, with…

Potential climatic mechanisms associated with the mega drought at 4200 cal yr BP: linking proxy data with modern climate analogues

NASA Astrophysics Data System (ADS)

Carter, V.; Shinker, J. J.

2017-12-01

Roughly 4200 years ago, a 150-year long mega drought occurred in the central Rocky Mountains, as indicated by pollen evidence from lake sediments from Long Lake, south-eastern Wyoming. However, pollen evidence does not record the climate mechanisms that caused the drought; they only provide evidence that the drought occurred. A modern climate analogue technique using North American Regional Reanalysis data was applied to the sedimentary data in order to identify possible synoptic and dynamic patterns that may have caused the mega drought at 4200 cal yr BP. Our results suggest warm and dry conditions were a result of anomalously higher-than-normal geopotential heights that were centred over the Great Plains beginning in the spring and persisting through the fall. Drought conditions during the growing seasons was the result of the anomalous high-pressure ridge, which suppressed moisture transport via the low level jet from the Gulf of Mexico, as well as brought in dry continental air from in the interior region of North America. The conditions associated with modern analogues offer a potential climate mechanism that caused the mega drought 4200 years ago, and likely led to the changes in vegetation composition as evidenced by the pollen record from Long Lake, Wyoming.

Modeling the formation and aging of secondary organic aerosols in Los Angeles during CalNex 2010

NASA Astrophysics Data System (ADS)

Hayes, P. L.; Carlton, A. G.; Baker, K. R.; Ahmadov, R.; Washenfelder, R. A.; Alvarez, S.; Rappengluck, B.; Gilman, J. B.; Kuster, W. C.; de Gouw, J. A.; Zotter, P.; Prevot, A. S. H.; Szidat, S.; Kleindienst, T. E.; Offenberg, J. H.; Ma, P. K.; Jimenez, J. L.

2015-05-01

Four different literature parameterizations for the formation and evolution of urban secondary organic aerosol (SOA) frequently used in 3-D models are evaluated using a 0-D box model representing the Los Angeles metropolitan region during the California Research at the Nexus of Air Quality and Climate Change (CalNex) 2010 campaign. We constrain the model predictions with measurements from several platforms and compare predictions with particle- and gas-phase observations from the CalNex Pasadena ground site. That site provides a unique opportunity to study aerosol formation close to anthropogenic emission sources with limited recirculation. The model SOA that formed only from the oxidation of VOCs (V-SOA) is insufficient to explain the observed SOA concentrations, even when using SOA parameterizations with multi-generation oxidation that produce much higher yields than have been observed in chamber experiments, or when increasing yields to their upper limit estimates accounting for recently reported losses of vapors to chamber walls. The Community Multiscale Air Quality (WRF-CMAQ) model (version 5.0.1) provides excellent predictions of secondary inorganic particle species but underestimates the observed SOA mass by a factor of 25 when an older VOC-only parameterization is used, which is consistent with many previous model-measurement comparisons for pre-2007 anthropogenic SOA modules in urban areas. Including SOA from primary semi-volatile and intermediate-volatility organic compounds (P-S/IVOCs) following the parameterizations of Robinson et al. (2007), Grieshop et al. (2009), or Pye and Seinfeld (2010) improves model-measurement agreement for mass concentration. The results from the three parameterizations show large differences (e.g., a factor of 3 in SOA mass) and are not well constrained, underscoring the current uncertainties in this area. Our results strongly suggest that other precursors besides VOCs, such as P-S/IVOCs, are needed to explain the observed

Evolutionary history of callose synthases in terrestrial plants with emphasis on proteins involved in male gametophyte development

PubMed Central

Honys, David

2017-01-01

Callose is a plant-specific polysaccharide (β-1,3-glucan) playing an important role in angiosperms in many developmental processes and responses to biotic and abiotic stresses. Callose is synthesised at the plasma membrane of plant cells by callose synthase (CalS) and, among others, represents the main polysaccharide in the callose wall surrounding the tetrads of developing microspores and in the growing pollen tube wall. CalS proteins involvement in spore development is a plesiomorphic feature of terrestrial plants, but very little is known about their evolutionary origin and relationships amongst the members of this protein family. We performed thorough comparative analyses of callose synthase family proteins from major plant lineages to determine their evolutionary history across the plant kingdom. A total of 1211 candidate CalS sequences were identified and compared amongst diverse taxonomic groups of plants, from bryophytes to angiosperms. Phylogenetic analyses identified six main clades of CalS proteins and suggested duplications during the evolution of specialised functions. Twelve family members had previously been identified in Arabidopsis thaliana. We focused on five CalS subfamilies directly linked to pollen function and found that proteins expressed in pollen evolved twice. CalS9/10 and CalS11/12 formed well-defined clades, whereas pollen-specific CalS5 was found within subfamilies that mostly did not express in mature pollen vegetative cell, although were found in sperm cells. Expression of five out of seven mature pollen-expressed CalS genes was affected by mutations in bzip transcription factors. Only three subfamilies, CalS5, CalS10, and CalS11, however, formed monophyletic, mostly conserved clades. The pairs CalS9/CalS10, CalS11/CalS12 and CalS3 may have diverged after angiosperms diversified from lycophytes and bryophytes. Our analysis of fully sequenced plant proteins identified new evolutionary lineages of callose synthase subfamilies and has

Last Deglaciation Events (16.1-11.4 cal-Ka) Recorded in a Speleothem from DeSoto Caverns, Alabama, U.S.A.

NASA Astrophysics Data System (ADS)

Lambert, W. J.; Aharon, P.; Hellstrom, J.

2007-12-01

Whereas the rapid climate swings that occurred during the last deglaciation have been well documented in the Greenland ice cores, their cause/s continue to be a subject of heated debate. Clearly, more geographically dispersed records are required in order to provide better insight into the history of deglaciation, and by extension into the cause/s of the abrupt climate shifts. Particularly scarce are continental deglaciation records from the southeast North America whose atmospheric conditions were controlled by the retreating Laurentide Ice Sheet to the north and the Gulf of Mexico warm waters to the south. In order to remedy the absence of deglaciation records in the Southeast USA in general, and the Gulf Coast in particular, we have initiated a study of a 55-cm long stalagmite (DSSG-2) from the DeSoto Caverns in Childersburg, Alabama (33° 18'N, 86° 17'W). Seven radiocarbon AMS and eighteen U/Th TIMS dates reveal that the continuously layered stalagmite covers the time interval 31 to 11.4 cal-Ka at growth rates varying from 61 μm/decade at the start of deglaciation and up to 2700 μm/decade close to its termination. The combination of unusually high growth rates, pristine aragonite mineralogy and tight sampling (n=602) afforded generation of high fidelity δ13C and δ18O records from about 16.1 to 11.4 cal-Ka whose high resolution is comparable with the contemporaneous Greenland ice core records. The stalagmite δ18O record shows excellent agreement in relative amplitude shifts and timing of abrupt and brief cold reversals (Oldest Dryas, Older Dryas, Inter-Allerød Cold Period) that punctuated the overall trend of deglaciation warming (Bølling/Allerød period). The succeeding Younger Dryas is depicted in the stalagmite by rapid positive shifts in δ18O and δ13C of 1.3‰ and 2.3‰ (V-PDB) relative to the baseline mean value and its start and termination (12.7-11.8 Ka) are concordant within error with the dates reported from GISP2 ice core (12.82-11.60 Ka

Rationale behind the near-ideal catalysis of Candida antarctica lipase A (CAL-A) for highly concentrating ω-3 polyunsaturated fatty acids into monoacylglycerols.

PubMed

He, Yongjin; Li, Jingbo; Kodali, Sitharam; Chen, Bilian; Guo, Zheng

2017-03-15

Dramatic decline in the quality and quantity of ω-3 PUFAs from marine resource demands new environmental-friendly technology to produce high quality ω-3 PUFAs concentrates in a better bioavailable form. Accordingly this work demonstrated an exceptionally highly efficient non-aqueous approach that non-regiospecific and non ω-3 PUFAs preferential Candida antarctica lipase A (CAL-A), functioning as a near-ideal biocatalyst, is capable to directly concentrate ω-3 PUFAs from 20% to 30% in oils to up to >90% in monoacylglycerols form through one step reaction. The rationale behind the experimental observation is justified and the catalytic property and specificity of an ideal enzyme tackling this task are defined. High selectivity and efficiency, excellent reusability of biocatalyst, general applicability for concentrating ω-3 PUFAs from both fish and microalgae oils, simple process for product recovery (e.g. by short path distillation), make this novel approach a highly industrially relevant and with potential application in food and drug industries. Copyright © 2016 Elsevier Ltd. All rights reserved.

Comparison of Mixed Layer Heights from Airborne High Spectral Resolution Lidar, Ground-based Measurements, and the WRP-Chem Model during CalNex and CARES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scarino, Amy Jo; Obland, Michael; Fast, Jerome D.

2014-06-05

The California Research at the Nexus of Air Quality and Climate Change (CalNex) and Carbonaceous Aerosol and Radiative Effects Study (CARES) field campaigns during May and June 2010 provided a data set appropriate for studying characteristics of the planetary boundary layer (PBL). The NASA Langley Research Center (LaRC) airborne High Spectral Resolution Lidar (HSRL) was deployed to California onboard the NASA LaRC B-200 aircraft to aid incharacterizing aerosol properties during these two field campaigns. Measurements of aerosol extinction (532 nm), backscatter (532 and 1064 nm), and depolarization (532 and 1064 nm) profiles during 31 flights, many in coordination with othermore » research aircraft and ground sites, constitute a diverse data set for use in characterizing the spatial and temporal distribution of aerosols, as well as the depth and variability of the daytime mixed layer (ML), which is a subset within the PBL. This work illustrates the temporal and spatial variability of the ML in the vicinity of Los Angeles and Sacramento, CA. ML heights derived from HSRL measurements are compared to PBL heights derived from radiosonde profiles, ML heights measured from ceilometers, and simulated PBL heights from the Weather Research and Forecasting Chemistry (WRF-Chem) community model. Comparisons between the HSRL ML heights and the radiosonde profiles in Sacramento result in a correlation coefficient value (R) of 0.93 (root7 mean-square (RMS) difference of 157 m and bias difference (HSRL radiosonde) of 5 m). HSRL ML heights compare well with those from the ceilometer in the LA Basin with an R of 0.89 (RMS difference of 108 m and bias difference (HSRL Ceilometer) of -9.7 m) for distances of up to 30 km between the B-200 flight track and the ceilometer site. Simulated PBL heights from WRF-Chem were compared with those obtained from all flights for each campaign, producing an R of 0.58 (RMS difference of 604 m and a bias difference (WRF-Chem HSRL) of -157 m) for Cal

Comparison of mixed layer heights from airborne high spectral resolution lidar, ground-based measurements, and the WRF-Chem model during CalNex and CARES

NASA Astrophysics Data System (ADS)

Scarino, A. J.; Obland, M. D.; Fast, J. D.; Burton, S. P.; Ferrare, R. A.; Hostetler, C. A.; Berg, L. K.; Lefer, B.; Haman, C.; Hair, J. W.; Rogers, R. R.; Butler, C.; Cook, A. L.; Harper, D. B.

2013-05-01

The California Research at the Nexus of Air Quality and Climate Change (CalNex) and Carbonaceous Aerosol and Radiative Effects Study (CARES) field campaigns during May and June 2010 provided a data set appropriate for studying characteristics of the planetary boundary layer (PBL). The NASA Langley Research Center (LaRC) airborne High Spectral Resolution Lidar (HSRL) was deployed to California onboard the NASA LaRC B-200 aircraft to aid in characterizing aerosol properties during these two field campaigns. Measurements of aerosol extinction (532 nm), backscatter (532 and 1064 nm), and depolarization (532 and 1064 nm) profiles during 31 flights, many in coordination with other research aircraft and ground sites, constitute a diverse data set for use in characterizing the spatial and temporal distribution of aerosols, as well as the depth and variability of the daytime mixed layer (ML), which is a subset within the PBL. This work illustrates the temporal and spatial variability of the ML in the vicinity of Los Angeles and Sacramento, CA. ML heights derived from HSRL measurements are compared to PBL heights derived from radiosonde profiles, ML heights measured from ceilometers, and simulated PBL heights from the Weather Research and Forecasting Chemistry (WRF-Chem) community model. Comparisons between the HSRL ML heights and the radiosonde profiles in Sacramento result in a correlation coefficient value (R) of 0.93 (root-mean-square (RMS) difference of 157 m and bias difference (HSRL - radiosonde) of 57 m). HSRL ML heights compare well with those from the ceilometer in the LA Basin with an R of 0.89 (RMS difference of 108 m and bias difference (HSRL - Ceilometer) of -9.7 m) for distances of up to 30 km between the B-200 flight track and the ceilometer site. Simulated PBL heights from WRF-Chem were compared with those obtained from all flights for each campaign, producing an R of 0.58 (RMS difference of 604 m and a bias difference (WRF-Chem - HSRL) of -157 m) for Cal

The Effects of Classroom Research by Part-Time Faculty upon the Retention of Adult Learners. Practitioner-Based Research Report.

ERIC Educational Resources Information Center

Kelly, Diana K.

In 1990, a study was conducted at Fullerton College (FC), a large suburban community college in Southern California, to determine if the use of classroom research by part-time faculty would stimulate greater involvement in learning and increase the course completion rate of adult learners in evening classes. A group of 16 part-time faculty…

Transition state characterization for the reversible binding of dihydrogen to bis(2,2'-bipyridine)rhodium(I) from temperature- and pressure-dependent experimental and theoretical studies.

PubMed

Fujita, Etsuko; Brunschwig, Bruce S; Creutz, Carol; Muckerman, James T; Sutin, Norman; Szalda, David; van Eldik, Rudi

2006-02-20

Thermodynamic and kinetic parameters for the oxidative addition of H2 to [Rh(I)(bpy)2]+ (bpy = 2,2'-bipyridine) to form [Rh(III)(H)2(bpy)2]+ were determined from either the UV-vis spectrum of equilibrium mixtures of [Rh(I)(bpy)2]+ and [Rh(III)(H)2(bpy)2]+ or from the observed rates of dihydride formation following visible-light irradiation of solutions containing [Rh(III)(H)2(bpy)2]+ as a function of H2 concentration, temperature, and pressure in acetone and methanol. The activation enthalpy and entropy in methanol are 10.0 kcal mol(-1) and -18 cal mol(-1) K(-1), respectively. The reaction enthalpy and entropy are -10.3 kcal mol(-1) and -19 cal mol(-1) K(-1), respectively. Similar values were obtained in acetone. Surprisingly, the volumes of activation for dihydride formation (-15 and -16 cm(3) mol(-1) in methanol and acetone, respectively) are very close to the overall reaction volumes (-15 cm(3) mol(-1) in both solvents). Thus, the volumes of activation for the reverse reaction, elimination of dihydrogen from the dihydrido complex, are approximately zero. B3LYP hybrid DFT calculations of the transition-state complex in methanol and similar MP2 calculations in the gas phase suggest that the dihydrogen has a short H-H bond (0.823 and 0.810 Angstroms, respectively) and forms only a weak Rh-H bond (1.866 and 1.915 Angstroms, respectively). Equal partial molar volumes of the dihydrogenrhodium(I) transition state and dihydridorhodium(III) can account for the experimental volume profile found for the overall process.

United States Air Force Summary, First Edition

DTIC Science & Technology

1976-01-01

Montoya, Joseph M. (N. Max.) Inouye, DanIel K. (Hawaii) Hollings, &nest F. (S.C.) Bayh, Birch (Ind.) Eagleton, ThomasF. (Mo.) Chiles, Lawton (Fla...0334 REF4 AF/ACBM~350 HOUSE APPROPRIATIONS. COMMITTEE Democrats Mohon, George H. (Tex.) Chairmm Whitten, Jamie L. (Miss.) Sikes, RobertL. F. (Fla...S.C.) Bellmon, Henry t., (okle.) Dole, Bob (Kans.) Beall, J. Glenn, Jr. (MD) ~ublicans Cranston, Alan (Cal.) Chiles, lawton (Fla.) Abourezk, James

The stability of hydrogen ion and specific conductance in filtered wet-deposition samples stored at ambient temperatures

USGS Publications Warehouse

Gordon, J.D.; Schroder, L.J.; Morden-Moore, A. L.; Bowersox, V.C.

1995-01-01

Separate experiments by the U.S. Geological Survey (USGS) and the Illinois State Water Survey Central Analytical Laboratory (CAL) independently assessed the stability of hydrogen ion and specific conductance in filtered wet-deposition samples stored at ambient temperatures. The USGS experiment represented a test of sample stability under a diverse range of conditions, whereas the CAL experiment was a controlled test of sample stability. In the experiment by the USGS, a statistically significant (?? = 0.05) relation between [H+] and time was found for the composited filtered, natural, wet-deposition solution when all reported values are included in the analysis. However, if two outlying pH values most likely representing measurement error are excluded from the analysis, the change in [H+] over time was not statistically significant. In the experiment by the CAL, randomly selected samples were reanalyzed between July 1984 and February 1991. The original analysis and reanalysis pairs revealed that [H+] differences, although very small, were statistically different from zero, whereas specific-conductance differences were not. Nevertheless, the results of the CAL reanalysis project indicate there appears to be no consistent, chemically significant degradation in sample integrity with regard to [H+] and specific conductance while samples are stored at room temperature at the CAL. Based on the results of the CAL and USGS studies, short-term (45-60 day) stability of [H+] and specific conductance in natural filtered wet-deposition samples that are shipped and stored unchilled at ambient temperatures was satisfactory.

Enhancing Diversity in Biomedical Data Science

PubMed Central

Canner, Judith E.; McEligot, Archana J.; Pérez, María-Eglée; Qian, Lei; Zhang, Xinzhi

2017-01-01

The gap in educational attainment separating underrepresented minorities from Whites and Asians remains wide. Such a gap has significant impact on workforce diversity and inclusion among cross-cutting Biomedical Data Science (BDS) research, which presents great opportunities as well as major challenges for addressing health disparities. This article provides a brief description of the newly established National Institutes of Health Big Data to Knowledge (BD2K) diversity initiatives at four universities: California State University, Monterey Bay; Fisk University; University of Puerto Rico, Río Piedras Campus; and California State University, Fullerton. We emphasize three main barriers to BDS careers (ie, preparation, exposure, and access to resources) experienced among those pioneer programs and recommendations for possible solutions (ie, early and proactive mentoring, enriched research experience, and data science curriculum development). The diversity disparities in BDS demonstrate the need for educators, researchers, and funding agencies to support evidence-based practices that will lead to the diversification of the BDS workforce PMID:28439180

Possible cases of leprosy from the Late Copper Age (3780-3650 cal BC) in Hungary.

PubMed

Köhler, Kitti; Marcsik, Antónia; Zádori, Péter; Biro, Gergely; Szeniczey, Tamás; Fábián, Szilvia; Serlegi, Gábor; Marton, Tibor; Donoghue, Helen D; Hajdu, Tamás

2017-01-01

At the Abony-Turjányos dűlő site, located in Central Hungary, a rescue excavation was carried out. More than 400 features were excavated and dated to the Protoboleráz horizon, at the beginning of the Late Copper Age in the Carpathian Basin, between 3780-3650 cal BC. Besides the domestic and economic units, there were two special areas, with nine-nine pits that differed from the other archaeological features of the site. In the northern pit group seven pits contained human remains belonging to 48 individuals. Some of them were buried carefully, while others were thrown into the pits. The aim of this study is to present the results of the paleopathological and molecular analysis of human remains from this Late Copper Age site. The ratio of neonates to adults was high, 33.3%. Examination of the skeletons revealed a large number of pathological cases, enabling reconstruction of the health profile of the buried individuals. Based on the appearance and frequency of healed ante- and peri mortem trauma, inter-personal (intra-group) violence was characteristic in the Abony Late Copper Age population. However other traces of paleopathology were observed on the bones that appear not to have been caused by warfare or inter-group violence. The remains of one individual demonstrated a rare set of bone lesions that indicate the possible presence of leprosy (Hansen's disease). The most characteristic lesions occurred on the bones of the face, including erosion of the nasal aperture, atrophy of the anterior nasal spine, inflammation of the nasal bone and porosity on both the maxilla and the bones of the lower legs. In a further four cases, leprosy infection is suspected but other infections cannot be excluded. The morphologically diagnosed possible leprosy case significantly modifies our knowledge about the timescale and geographic spread of this specific infectious disease. However, it is not possible to determine the potential connections between the cases of possible leprosy

Characterization of Microbes Capable of Using Vinyl Chloride and Ethene as Sole Carbon and Energy Sources by Anaerobic Oxidation

DTIC Science & Technology

2013-09-01

Water , Inc. Stephen Zinder Heather Fullerton Cornell University This report was prepared under contract to the Department of Defense...2.4.6 Preparation of Autoclaved and Water Controls ....................................... 20 2.5 Anaerobic Ethene Enrichment Cultures Based...amended with 5 mM sulfate or unamended in comparison with an uninoculated water blank (abiotic). Arrows represent an addition of ethene

Women's Access to Higher Education Leadership: Cultural and Structural Barriers

ERIC Educational Resources Information Center

Ballenger, Julia

2010-01-01

The Labor Force 2008 projections reflected that the rate of growth for women in the labor force will increase at a faster rate than that of men (Fullerton, 1999). In 2008, the majority of employed women (39 percent) worked in management, professional, and related occupations (U.S. Department of Labor, 2008). Although women's participation in the…

Information Navigation 101

ERIC Educational Resources Information Center

Foster, Andrea L.

2007-01-01

Fullerton, California--College students use technology constantly. They text-message friends, compile playlists for their iPods, and are whizzes at updating their MySpace profiles. But when it comes to one kind of work they are required to do in college--namely, academic research--they can be inept. Too often, college officials say, students rely…

Retrievals of Sea Surface Emissivity and Skin Temperature from M-AERI Observations from the ACAPEX/CalWater2 Campaign

NASA Astrophysics Data System (ADS)

Gero, P. J.; Westphall, M.; Knuteson, R.; Knuteson, R. O.; Smith, W.

2016-12-01

The Atmospheric Emitted Radiance Interferometer (AERI) is a ground-based instrument developed at the University of Wisconsin-Madison that measures downwelling thermal infrared radiance from the atmosphere. Observations are made in the 520-3020 cm-1 (3.3-19 μm) spectral range with a resolution of 1 cm-1, with an accuracy better than 1% of ambient radiance. These observations can be used to obtain vertical profiles of tropospheric temperature and water vapor in the lowest 3 km of the troposphere, as well as measurements of the concentration of various trace gases and microphysical and optical properties of clouds and aerosols. The U.S Department of Energy's (DOE) Atmospheric Radiation Measurement (ARM) program currently operates about ten AERIs at various fixed and mobile sites worldwide, addressing a diverse range of scientific goals from process studies to long-term climate observations. One of the instruments is a marine version (M-AERI) that has the capability to view scenes ±45° from the horizon, and can be used to observe sea surface properties such as skin temperature and emissivity. The M-AERI was deployed on the NOAA Ship Ronald Brown in 2015 as part of the ACAPEX/CalWater2 campaign to study atmospheric rivers in the Pacific Ocean. We present results from the M-AERI from this campaign of retrievals of skin temperature and sea surface emissivity as a function of view angle and wind speed, as well as comparisons to various models.

Extreme Energy Particle Astrophysics with ANITA-V

NASA Astrophysics Data System (ADS)

Wissel, Stephanie

This proposal is in collaboration with Peter Gorham at the University of Hawaii, who is the PI of the lead proposal. Co-I Wissel and her group at California Polytechnic State University (Cal Poly) will be responsible for calibration equipment upgrades, calibration equipment, and deployment of the calibration system. The Cal Poly group is planning to provide calibration hardware and software products in support of the analysis of ANITAV data in search of ultra high-energy (UHE) neutrinos and cosmic rays. Wissel (now at Cal Poly, a new collaborating institution for ANITA-5) brings significant experience in the detection of high-energy and ultra-high energy particles to the collaboration, leveraging her thirteen years of experience in particle astrophysics and previous work on ANITA-III and ANITA-IV.

Optical Sensing of the Fatigue Damage State of CFRP under Realistic Aeronautical Load Sequences

PubMed Central

Zuluaga-Ramírez, Pablo; Arconada, Álvaro; Frövel, Malte; Belenguer, Tomás; Salazar, Félix

2015-01-01

We present an optical sensing methodology to estimate the fatigue damage state of structures made of carbon fiber reinforced polymer (CFRP), by measuring variations on the surface roughness. Variable amplitude loads (VAL), which represent realistic loads during aeronautical missions of fighter aircraft (FALSTAFF) have been applied to coupons until failure. Stiffness degradation and surface roughness variations have been measured during the life of the coupons obtaining a Pearson correlation of 0.75 between both variables. The data were compared with a previous study for Constant Amplitude Load (CAL) obtaining similar results. Conclusions suggest that the surface roughness measured in strategic zones is a useful technique for structural health monitoring of CFRP structures, and that it is independent of the type of load applied. Surface roughness can be measured in the field by optical techniques such as speckle, confocal perfilometers and interferometry, among others. PMID:25760056

CalMHSA Student Mental Health Campus-Wide Survey. 2013 Summary Report

ERIC Educational Resources Information Center

Sontag-Padilla, Lisa; Roth, Elizabeth; Woodbridge, Michelle W.; Kase, Courtney Ann; Osilla, Karen Chan; D'Amico, Elizabeth; Jaycox, Lisa H.; Stein, Bradley D.

2014-01-01

Mental Health Problems among college and university students represent a significant public health issue in the United States. Mental disorders account for nearly one-half of the disease burden for young adults in the United States (World Health Organization, 2008), and most lifetime mental disorders have first onset by age 24 (Kessler et al.,…

Bayesian chronological analyses consistent with synchronous age of 12,835–12,735 Cal B.P. for Younger Dryas boundary on four continents

PubMed Central

Kennett, James P.; Kennett, Douglas J.; Culleton, Brendan J.; Aura Tortosa, J. Emili; Bischoff, James L.; Bunch, Ted E.; Daniel, I. Randolph; Erlandson, Jon M.; Ferraro, David; Firestone, Richard B.; Goodyear, Albert C.; Israde-Alcántara, Isabel; Johnson, John R.; Jordá Pardo, Jesús F.; Kimbel, David R.; LeCompte, Malcolm A.; Lopinot, Neal H.; Mahaney, William C.; Moore, Andrew M. T.; Moore, Christopher R.; Ray, Jack H.; Stafford, Thomas W.; Tankersley, Kenneth Barnett; Wittke, James H.; Wolbach, Wendy S.; West, Allen

2015-01-01

The Younger Dryas impact hypothesis posits that a cosmic impact across much of the Northern Hemisphere deposited the Younger Dryas boundary (YDB) layer, containing peak abundances in a variable assemblage of proxies, including magnetic and glassy impact-related spherules, high-temperature minerals and melt glass, nanodiamonds, carbon spherules, aciniform carbon, platinum, and osmium. Bayesian chronological modeling was applied to 354 dates from 23 stratigraphic sections in 12 countries on four continents to establish a modeled YDB age range for this event of 12,835–12,735 Cal B.P. at 95% probability. This range overlaps that of a peak in extraterrestrial platinum in the Greenland Ice Sheet and of the earliest age of the Younger Dryas climate episode in six proxy records, suggesting a causal connection between the YDB impact event and the Younger Dryas. Two statistical tests indicate that both modeled and unmodeled ages in the 30 records are consistent with synchronous deposition of the YDB layer within the limits of dating uncertainty (∼100 y). The widespread distribution of the YDB layer suggests that it may serve as a datum layer. PMID:26216981

The state of Pluto's atmosphere in 2012-2013

NASA Astrophysics Data System (ADS)

Bosh, A. S.; Person, M. J.; Levine, S. E.; Zuluaga, C. A.; Zangari, A. M.; Gulbis, A. A. S.; Schaefer, G. H.; Dunham, E. W.; Babcock, B. A.; Davis, A. B.; Pasachoff, J. M.; Rojo, P.; Servajean, E.; Förster, F.; Oswalt, T.; Batcheldor, D.; Bell, D.; Bird, P.; Fey, D.; Fulwider, T.; Geisert, E.; Hastings, D.; Keuhler, C.; Mizusawa, T.; Solenski, P.; Watson, B.

2015-01-01

We observed two stellar occultations on UT 4 May 2013 and UT 9 September 2012, with the aim of measuring Pluto's atmospheric parameters. Both of these events were observed by world-wide collaborations of many observers, and both occurred within 1 month of Pluto's stationary points. The PC20120909 event was observed at the McDonald Observatory (MONET 1.2-m), and Olin Observatory (the Ortega 0.8-m); the P20130504 event was observed at the Las Campanas Observatory (du Pont 2.5-m), the Cerro Tololo Inter-American Observatory (SMARTS 1-m), and the Cerro Calán National Astronomical Observatory (Goto 0.45-m). Analysis of the data indicates an atmospheric state similar to that in June 2011. The shadow radius for the event is unchanged from recent events, indicating an atmosphere that is holding stable and not in the midst of global collapse. We discuss the advantages and disadvantages of comparing various atmospheric parameters across events (the shadow radius vs. the pressure at a particular radius). These analyses suggest that Pluto will still have an atmosphere when the New Horizons spacecraft arrives in July 2015.

Surface-exposure ages of Front Range moraines that may have formed during the Younger Dryas, 8.2 cal ka, and Little Ice Age events

USGS Publications Warehouse

Benson, L.; Madole, R.; Kubik, P.; McDonald, R.

2007-01-01

Surface-exposure (10Be) ages have been obtained on boulders from three post-Pinedale end-moraine complexes in the Front Range, Colorado. Boulder rounding appears related to the cirque-to-moraine transport distance at each site with subrounded boulders being typical of the 2-km-long Chicago Lakes Glacier, subangular boulders being typical of the 1-km-long Butler Gulch Glacier, and angular boulders being typical of the few-hundred-m-long Isabelle Glacier. Surface-exposure ages of angular boulders from the Isabelle Glacier moraine, which formed during the Little Ice Age (LIA) according to previous lichenometric dating, indicate cosmogenic inheritance values ranging from 0 to ???3.0 10Be ka.11Surface-exposure ages in this paper are labeled 10Be; radiocarbon ages are labeled 14C ka, calendar and calibrated radiocarbon ages are labeled cal ka, and layer-based ice-core ages are labeled ka. 14C ages, calibrated 14C ages, and ice core ages are given relative to AD 1950, whereas 10Be ages are given relative to the sampling date. Radiocarbon ages were calibrated using CALIB 5.01 and the INTCAL04 data base Stuiver et al. (2005). Ages estimated using CALIB 5.01 are shown in terms of their 1-sigma range. Subangular boulders from the Butler Gulch end moraine yielded surface-exposure ages ranging from 5 to 10.2 10Be ka. We suggest that this moraine was deposited during the 8.2 cal ka event, which has been associated with outburst floods from Lake Agassiz and Lake Ojibway, and that the large age range associated with the Butler Gulch end moraine is caused by cosmogenic shielding of and(or) spalling from boulders that have ages in the younger part of the range and by cosmogenic inheritance in boulders that have ages in the older part of the range. The surface-exposure ages of eight of nine subrounded boulders from the Chicago Lakes area fall within the 13.0-11.7 10Be ka age range, and appear to have been deposited during the Younger Dryas interval. The general lack of inheritance in

Modeling the formation and aging of secondary organic aerosols in Los Angeles during CalNex 2010

DOE PAGES

Hayes, P. L.; Carlton, A. G.; Baker, K. R.; ...

2015-05-26

Four different literature parameterizations for the formation and evolution of urban secondary organic aerosol (SOA) frequently used in 3-D models are evaluated using a 0-D box model representing the Los Angeles metropolitan region during the California Research at the Nexus of Air Quality and Climate Change (CalNex) 2010 campaign. We constrain the model predictions with measurements from several platforms and compare predictions with particle- and gas-phase observations from the CalNex Pasadena ground site. That site provides a unique opportunity to study aerosol formation close to anthropogenic emission sources with limited recirculation. The model SOA that formed only from the oxidationmore » of VOCs (V-SOA) is insufficient to explain the observed SOA concentrations, even when using SOA parameterizations with multi-generation oxidation that produce much higher yields than have been observed in chamber experiments, or when increasing yields to their upper limit estimates accounting for recently reported losses of vapors to chamber walls. The Community Multiscale Air Quality (WRF-CMAQ) model (version 5.0.1) provides excellent predictions of secondary inorganic particle species but underestimates the observed SOA mass by a factor of 25 when an older VOC-only parameterization is used, which is consistent with many previous model–measurement comparisons for pre-2007 anthropogenic SOA modules in urban areas. Including SOA from primary semi-volatile and intermediate-volatility organic compounds (P-S/IVOCs) following the parameterizations of Robinson et al. (2007), Grieshop et al. (2009), or Pye and Seinfeld (2010) improves model–measurement agreement for mass concentration. The results from the three parameterizations show large differences (e.g., a factor of 3 in SOA mass) and are not well constrained, underscoring the current uncertainties in this area. Our results strongly suggest that other precursors besides VOCs, such as P-S/IVOCs, are needed to explain the

Submicron organic aerosol in Tijuana, Mexico, from local and Southern California sources during the CalMex campaign

NASA Astrophysics Data System (ADS)

Takahama, S.; Johnson, A.; Guzman Morales, J.; Russell, L. M.; Duran, R.; Rodriguez, G.; Zheng, J.; Zhang, R.; Toom-Sauntry, D.; Leaitch, W. R.

2013-05-01

The CalMex campaign was conducted from May 15 to June 30 of 2010 to study the properties and sources of air pollution in Tijuana, Mexico. In this study, submicron organic aerosol mass (OM) composition measured by Fourier Transform Infrared Spectroscopy (FTIR), Aerosol Chemical Speciation Monitor (ACSM), and X-ray spectromicroscopy are combined with statistical analysis and measurements of other atmospheric constituents. The average (±one standard deviation) OM concentration was 3.3 ± 1.7 μg m-3. A large source of submicron aerosol mass at this location was determined to be vehicular sources, which contributed approximately 40% to the submicron OM; largely during weekday mornings. The O/C ratio estimated from ACSM measurements was 0.64 ± 0.19; diurnal variations in this value and the more oxygenated fraction of OM as determined from Positive Matrix Factorization and classification analyses suggest the high degree of oxygenation originates from aged OM, rather than locally-produced secondary organic aerosol. A large contribution of this oxygenated aerosol to Tijuana from various source classes was observed; some fraction of this aerosol mass may be associated with non-refractory components, such as dust or BC. Backtrajectory simulations using the HYSPLIT model suggest that the mean wind vector consistently originated from the northwest region, over the Pacific Ocean and near the Southern California coast, which suggests that the origin of much of the oxygenated organic aerosol observed in Tijuana (as much as 60% of OM) may have been the Southern California Air Basin. The marine aerosol contribution to OM during the period was on average 23 ± 24%, though its contribution varied over synoptic rather than diurnal timescales. BB aerosol contributed 20 ± 20% of the OM during the campaign period, with notable BB events occurring during several weekend evenings.

Predicting Pilot Retention

DTIC Science & Technology

2012-06-15

forever… Gig ‘Em! Dale W. Stanley III vii Table of Contents Page Acknowledgments...over the last 20 years. Airbus predicted that these trends would continue as emerging economies , especially in Asia, were creating a fast growing...US economy , pay differential and hiring by the major airlines contributed most to the decision to separate from the Air Force (Fullerton, 2003: 354

Investigations of Photovoltaic Ferroelectric-Semiconductor Nonvolatile Memory.

DTIC Science & Technology

1981-03-01

HEWLETT-PACKARD BOX 3310 100 MARKET ST APT 1 3404 EAST HARMONY RD2U ATTN J. M. KIRSCH, MTS ATTN R. SCHAEFER ATTN L. W. JAMES, MTS FULLERTON, CA 92633...RADIO SYS SPERRY UNICORN 1300 S ROGERS 367 ORCHARD STREET 52-21 65 PL AT’rN J. F. PRATHER, MGR CEN ATTN I. A. PAULL, ES ATTN W. BURSTEIN, ENGR

Activation of pollen tube callose synthase by detergents. Evidence for different mechanisms of action.

PubMed Central

Li, H; Bacic, A; Read, S M

1997-01-01

In pollen tubes of Nicotiana alata, a membrane-bound, Ca(2+)-independent callose synthase (CalS) is responsible for the biosynthesis of the (1,3)-beta-glucan backbone of callose, the main cell wall component. Digitonin increases CalS activity 3- to 4-fold over a wide range of concentrations, increasing the maximum initial velocity without altering the Michaelis constant for UDP-glucose. The CalS activity that requires digitonin for assay (the latent CalS activity) is not inhibited by the membrane-impermeant, active site-directed reagent UDP-pyridoxal when the reaction is conducted in the absence of digitonin. This is consistent with digitonin increasing CalS activity by the permeabilization of membrane vesicles. A second group of detergents, including 3-[(3-cholamidopropyl)dimethylammonio]-1-propane-sulfonate (CHAPS), Zwittergent 3-16, and 1-alpha-lysolecithin, activate pollen tube CalS 10- to 15-fold, but only over a narrow range of concentrations just below their respective critical micellar concentrations. This activation could not be attributed to any particular chemical feature of these detergents. CHAPS increases maximum initial velocity and decreases the Michaelis constant for UDP-glucose and activates CalS even in the presence of permeabilizing concentrations of digitonin. Inhibition studies with UDP-pyridoxal indicate that activation by CHAPS occurs by recruitment of previously inactive CalS molecules to the pool of active enzyme. The activation of pollen tube CalS by these detergents therefore resembles activation of the enzyme by trypsin. PMID:9276948

[Control of malaria transmission in a gold-mining area in Amapá State, Brazil, with participation by private enterprise].

PubMed

Couto AA; Calvosa, V S; Lacerda, R; Castro, F; Santa Rosa, E; Nascimento, J M

2001-01-01

This paper reports on the epidemiological characterization of malaria following implementation of a program to control the endemic in a gold-mining area in northern Amapá State. The study focuses on total malaria cases in Amapá and the impact of the disease on the population, as represented by the Mineração Novo Astro S/A company and its employees as well as the community of Vila de Lourenço in the municipality of Calçoene, and adjacent gold miners. The effect of control measures in the program area is indicated by a significant reduction in malaria incidence and malaria-related morbidity and mortality. The importance of participation by private enterprise is emphasized, particularly in large projects for the control of endemic diseases (notably malaria) in the Amazon Region.

A High-Level Language for Modeling Algorithms and Their Properties

NASA Astrophysics Data System (ADS)

Akhtar, Sabina; Merz, Stephan; Quinson, Martin

Designers of concurrent and distributed algorithms usually express them using pseudo-code. In contrast, most verification techniques are based on more mathematically-oriented formalisms such as state transition systems. This conceptual gap contributes to hinder the use of formal verification techniques. Leslie Lamport introduced PlusCal, a high-level algorithmic language that has the "look and feel" of pseudo-code, but is equipped with a precise semantics and includes a high-level expression language based on set theory. PlusCal models can be compiled to TLA + and verified using the model checker tlc.

Environmental Change recorded in Lacustrine Sediments from Tangra Yumco, Tibetan Plateau, at 16.5 ka cal BP and during the Younger Dryas Chronozone

NASA Astrophysics Data System (ADS)

Henkel, K.; Ahlborn, M.; Haberzettl, T.; Kasper, T.; Daut, G.; Ju, J.; Ma, Q.; Wang, J.; Zhu, L.; Maeusbacher, R.

2013-12-01

In the purpose of understanding the recent climate change on the Tibetan Plateau (TP) and beyond and to allow predictions for future climate scenarios it is imperative to investigate past climate changes. The numerous lake systems on the TP serve as ideal archives for past hydrological changes, which are assumed to be caused by variations in strength and extent of monsoonal air masses. By now, the spatial and temporal monsoonal evolution on the TP is intensively discussed. With the focus on a W-E lake transect on the southern TP we investigate lakes with a multi-dating and multi-proxy analyses approach, which has already been successfully carried out on Nam Co, the easternmost lake of the transect. In this study, we present results from a ~11.5 m long lacustrine sediment record from the terminal lake Tangra Yumco (4,540 m a.s.l., 31°13'N, 86°43'E), representing the center of the transect. Tangra Yumco is the deepest lake recorded on the TP so far. Via a hydro-acoustic survey observed submerged beach berms (45 m below recent lake level) and exposed lake level terraces up to ~205 m above lake level indicate large lake level fluctuations in the past. The record consists of an interbedding of fine grained silty sediments with a lamination of different thicknesses (sub-mm to cm) and partly intercalated blackish sandy layers. Homogeneous areas, which occur especially in the upper two thirds of the profile, represent turbidite deposits. Until now, color- and greyscale-, magnetic susceptibility- and XRF-scanning were applied. For age control 22 14C AMS-radiocarbon measurements were carried out on bulk organic matter. To determine a possible carbon reservoir effect, additional surface sediment samples were measured as well as one modern aquatic plant. The results indicate a reservoir effect of ~2,120 +110/-90 years. Assuming a constant reservoir effect, the base of the record reveals a corrected radiocarbon age of 17,270 +325/-310 cal BP. The sediment accumulation rate is

The impact of port emissions and marine biogenics on the single-particle chemistry of marine aerosol measured on board the R/V Atlantis during the CalNEX 2010 field campaign

NASA Astrophysics Data System (ADS)

Gaston, C. J.; Quinn, P.; Bates, T. S.; Prather, K. A.

2010-12-01

Marine environments are characterized by low particle concentrations and, as such, are sensitive to changes in particle number concentration and chemistry induced by biogenic and anthropogenic influences. Measurements of both gas phase and particle phase emissions on board the R/V Atlantis during the CalNEX 2010 field campaign provided an opportunity to examine the impact of anthropogenic and marine biogenic emissions on particle chemistry along the California coast. Real-time, single-particle measurements made using an aerosol time-of-flight mass spectrometer (ATOFMS) revealed the single-particle mixing state of the sampled marine aerosols. Submicron particles (0.2-1.0 um) containing organic carbon, elemental carbon mixed with organic carbon, and unique V-containing particles previously detected in port regions were prevalent throughout the Southern California coast; most of these particles were also associated with sulfate. Measurements made in the deep water channel near Sacramento, CA revealed dramatically different particle chemistry that was characterized by organic carbon and amines. Particles measured further away from the continent toward the open ocean were influenced by marine biological activity due to a phytoplankton bloom that was occurring off the California coast. During this sampling period, unique ocean-derived particles containing internal mixtures of Mg and organic carbon were detected in addition to unique particles containing elemental S ions, which were only detected at night. An aerosol generator used to bubble seawater in order to characterize primary emissions from the ocean confirmed that the Mg-organic carbon and S-containing particles were indeed emitted from the ocean. These measurements reveal the strong impact of both port emissions as well as marine biogenic emissions on aerosol chemistry along the California coast.

The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut.

PubMed

Beton, Daniela; Guzzo, Cristiane R; Ribeiro, Alberto F; Farah, Chuck S; Terra, Walter R

2012-09-01

Cathepsin L-like proteinases (CAL) are major digestive proteinases in the beetle Tenebrio molitor. Procathepsin Ls 2 (pCAL2) and 3 (pCAL3) were expressed as recombinant proteins in Escherichia coli, purified and activated under acidic conditions. Immunoblot analyses of different T. molitor larval tissues demonstrated that a polyclonal antibody to pCAL3 recognized pCAL3 and cathepsin L 3 (CAL3) only in the anterior two-thirds of midgut tissue and midgut luminal contents of T. molitor larvae. Furthermore, immunocytolocalization data indicated that pCAL3 occurs in secretory vesicles and microvilli in anterior midgut. Therefore CAL3, like cathepsin L 2 (CAL2), is a digestive enzyme secreted by T. molitor anterior midgut. CAL3 hydrolyses Z-FR-MCA and Z-RR-MCA (typical cathepsin substrates), whereas CAL2 hydrolyses only Z-FR-MCA. Active site mutants (pCAL2C25S and pCAL3C26S) were constructed by replacing the catalytic cysteine with serine to prevent autocatalytic processing. Recombinant pCAL2 and pCAL3 mutants (pCAL2C25S and pCAL3C26S) were prepared, crystallized and their 3D structures determined at 1.85 and 2.1 Å, respectively. While the overall structure of these enzymes is similar to other members of the papain superfamily, structural differences in the S2 subsite explain their substrate specificities. The data also supported models for CAL trafficking to lysosomes and to secretory vesicles to be discharged into midgut contents. Copyright © 2012 Elsevier Ltd. All rights reserved.

Rotational Spectrum and Internal Rotation Barrier of 1-Chloro-1,1-difluoroethane

NASA Astrophysics Data System (ADS)

Alonso, José L.; López, Juan C.; Blanco, Susana; Guarnieri, Antonio

1997-03-01

The rotational spectra of 1-chloro-1,1-difluoroethane (HCFC-142b) has been investigated in the frequency region 8-115 GHz with Stark, waveguide Fourier transform (FTMW), and millimeter-wave spectrometers. Assignments in large frequency regions with the corresponding frequency measurements have been made for the ground andv18= 1 (CH3torsion) vibrational states of the35Cl isotopomer and for the ground state of the37Cl species. Accurate rotational, quartic centrifugal distortion, and quadrupole coupling constants have been determined from global fits considering all these states. SmallA-Einternal rotation splittings have been observed for thev18= 1 vibrational state using FTMW spectroscopy. The barrier height for the internal rotation of the methyl group has been determined to be 3751 (4) cal mol-1, in disagreement with the previous microwave value of 4400 (100) cal mol-1reported by G. Graner and C. Thomas [J. Chem. Phys.49,4160-4167 (1968)].

Accuracy evaluation of a six-degree-of-freedom couch using cone beam CT and IsoCal phantom with an in-house algorithm.

PubMed

Zhang, Qinghui; Driewer, Joseph; Wang, Shuo; Li, Sicong; Zhu, Xiaofeng; Zheng, Dandan; Cao, Yijian; Zhang, Jiaju; Jamshidi, Abolghassem; Cox, Brett W; Knisely, Jonathan P S; Potters, Louis; Klein, Eric E

2017-08-01

The accuracy of a six degree of freedom (6DoF) couch was evaluated using a novel method. Cone beam CT (CBCT) images of a 3D phantom (IsoCal) were acquired with different, known combinations of couch pitch and roll angles. Pitch and roll angles between the maximum allowable values of 357 and 3 degrees were tested in one degree increments. A total of 49 combinations were tested at 0 degrees of yaw (couch rotation angle). The 3D positions of 16 tungsten carbide ball bearings (BBs), each 4 mm in diameter and arranged in a known geometry within the IsoCal phantom, were determined in the 49 image sets with in-house software. The BB positions at different rotation angles were determined using a rotation matrix from the original BB positions at zero pitch and roll angles. A linear least squares fit method estimated the rotation angles and differences between detected and nominal rotation angles were calculated. This study was conducted for the case with and without extra weight on the couch. Couch walk shifts for the system were investigated using eight combinations of rotation, roll and pitch. A total of 49 CBCT images with voxel sizes 0.5 × 0.5 × 1.0 mm 3 were taken for the case without extra weight on the couch. The 16 BBs were determined to evaluate the isocenter translation and rotation differences between the calculated and nominal couch values. Among all 49 calculations, the maximum rotation angle differences were 0.10 degrees for pitch, 0.15 degrees for roll and 0.09 degrees for yaw. The corresponding mean and standard deviation values were 0.028 ± 0.032, -0.043 ± 0.058, and -0.009 ± 0.033 degrees. The maximum translation differences were 0.3 mm in the left-right direction, 0.5 mm in the anterior-posterior direction and 0.4 mm in the superior-inferior direction. The mean values and corresponding standard deviations were 0.07 ± 0.12, -0.05 ± 0.25, and -0.12±0.14 mm for the planes described above. With an 80 kg phantom on the couch, the

30 CFR 905.773 - Requirements for permits and permit processing.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., 42 U.S.C. 7401 et seq California Air Pollution Control Laws, Cal. Health & Safety Code section 39000..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA... responsibilities under the following Federal laws with the relevant California State laws to avoid duplication...

30 CFR 905.773 - Requirements for permits and permit processing.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., 42 U.S.C. 7401 et seq California Air Pollution Control Laws, Cal. Health & Safety Code section 39000..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA... responsibilities under the following Federal laws with the relevant California State laws to avoid duplication...

30 CFR 905.773 - Requirements for permits and permit processing.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., 42 U.S.C. 7401 et seq California Air Pollution Control Laws, Cal. Health & Safety Code section 39000..., DEPARTMENT OF THE INTERIOR PROGRAMS FOR THE CONDUCT OF SURFACE MINING OPERATIONS WITHIN EACH STATE CALIFORNIA... responsibilities under the following Federal laws with the relevant California State laws to avoid duplication...

Computing Relative Free Energies of Solvation Using Single Reference Thermodynamic Integration Augmented with Hamiltonian Replica Exchange

DTIC Science & Technology

2010-10-21

paper assess the reversible works needed to alchemi - cally change each molecule to the benzene core reference state. To automate the alchemical...the alchemi - cal free energies or reversible works, the TI procedure split the interval from the real state of the molecule at λ ) 0 to the reference

Can California Teacher Pensions Be Distributed More Fairly? Research Report

ERIC Educational Resources Information Center

Johnson, Richard W.; Southgate, Benjamin G.

2014-01-01

The California State Teachers' Retirement System (CalSTRS) has been grossly underfunded for the past decade. State policymakers have responded by cutting plan benefits for new hires and raising teachers' required plan contributions. These changes, however, have undermined teachers' retirement income security. Only 35 percent of new hires will…

The effect of coracoacromial ligament excision and acromioplasty on the amount of rotator cuff force production necessary to restore intact glenohumeral biomechanics.

PubMed

Budoff, Jeffrey E; Lin, Cheng-Li; Hong, Chih-Kai; Chiang, Florence L; Su, Wei-Ren

2016-06-01

Coracoacromial ligament (CAL) excision and acromioplasty increase superior and anterosuperior glenohumeral translation. It is unknown how much of an increase in rotator cuff force production is required to re-establish intact glenohumeral biomechanics after these surgical procedures. We hypothesized that, after CAL excision and acromioplasty, an increase in rotator cuff force production would not be necessary to reproduce the anterosuperior and superior translations of the intact specimens. Nine cadaveric shoulders were subjected to loading in the superior and anterosuperior directions in the intact state after CAL excision, acromioplasty, and recording of the translations. The rotator cuff force was then increased to normalize glenohumeral biomechanics. After CAL excision at 150 and 200 N of loading, an increase in the rotator cuff force by 25% decreased anterosuperior translation to the point where there was no significant difference from the intact specimen's translation. After acromioplasty (and CAL excision) at 150 and 200 N, an increase in the rotator cuff force of 25% and 30%, respectively, decreased superior translation to the point where there was no significant difference from the intact specimen's translation. At 150 to 200 N of loading, CAL excision and acromioplasty increase the rotator cuff force required to maintain normal glenohumeral biomechanics by 25% to 30%. After a subacromial decompression, the rotator cuff has an increased force production requirement to maintain baseline glenohumeral mechanics. Under many circumstances, in vivo force requirements may be even greater after surgical attenuation of the coracoacromial arch. Basic Science Study; Biomechanics. Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Maintainability Prediction and Analysis Study. Revision A

DTIC Science & Technology

1978-07-01

Pliska, et al Huges Aircraft Company Fullerton, California July 1978 I. p -Vlt -. , . - . . . .. .. CONTENTS 8E CTION 0.0 SU MMAP.Y...per Operating Hour (IMWfl/OH) ........ ................ 78 iii I. .1 CONTENTS (Continued) SECTION 3.0 DATA COLLECTION 3.1 Definitionof Data Collected... basiL methodology for predicting Mmax (0) when an accurate representation of the overall repair time distribution is desired. The meth- odology

Pre-STS-3 press conference held at the JSC public affairs facility

NASA Image and Video Library

1982-01-25

S82-25903 (21 Jan. 1982) --- Astronaut Jack R. Lousma, center, and C. Gordon Fullerton, left, respond to a visual depicting the Columbia and its remote manipulator system in space during a pre-STS-3 press conference in JSC?s pubic affairs building. Dr. John Lawrence, public information specialist who introduced the crew to news media representatives, is at far right. Photo credit: NASA

An Analysis of Factors Affecting the Retention of Medical Officers in the United States Navy

DTIC Science & Technology

1986-12-01

Others, such as the Berry Plan <BP) and the Medi cal / Osteopathi c Scholarship Program (MOSP) were terminated in 1973 and 1977, respectively CRef. 15...Length-of -Servi ce Doctor of Osteopathy (OSTEO) Marital Status Age Medical School Eligible to Retire 66 VARIABLE SOURCE OF ENTRY PHYSICIAN SPECIALTY

The Cubans. Their History and Culture. CAL Refugee Fact Sheet Series No. 12.

ERIC Educational Resources Information Center

Robson, Barbara

This fact sheet is designed to give those working with newly arrived Cubans in the United States a brief refresher on Cuban geography and history, especially the history of Cuba's relations with the United States. It reviews events that have brought Cubans to the United States, and discusses the values newcomers are likely to have brought with…

Calcipotriol plus betamethasone dipropionate aerosol foam provides superior efficacy vs. gel in patients with psoriasis vulgaris: randomized, controlled PSO-ABLE study.

PubMed

Paul, C; Stein Gold, L; Cambazard, F; Kalb, R E; Lowson, D; Bang, B; Griffiths, C E M

2017-01-01

Fixed combination calcipotriol 50 μg/g (Cal) plus betamethasone 0.5 mg/g (BD) foam has been developed as a new treatment option for patients with psoriasis. The randomized, parallel-group, investigator-blinded Phase III, 12-week PSO-ABLE study compared the efficacy and safety of Cal/BD foam with Cal/BD gel. Patients aged ≥18 years with mild-to-severe psoriasis were randomized 4:4:1:1 to once-daily Cal/BD foam, Cal/BD gel, foam vehicle or gel vehicle (NCT02132936). The primary efficacy endpoint was the proportion of patients who were clear/almost clear with a ≥ 2 grade improvement according to the physician's global assessment of disease severity (i.e. treatment success) at week 4 for Cal/BD foam vs. week 8 for Cal/BD gel. Secondary efficacy endpoints included: proportion of patients achieving at least a 75% reduction in modified psoriasis area and severity index (mPASI75), and time to treatment success (TTTS). Safety was monitored throughout. A total of 463 patients were randomized: Cal/BD foam (n = 185), Cal/BD gel (n = 188), foam vehicle (n = 47), gel vehicle (n = 43); overall completion rate was 90%. Cal/BD foam achieved higher treatment success rates (38% vs. 22%; P < 0.001) and mPASI75 (52% vs. 35%; P < 0.001) by week 4 than Cal/BD gel by week 8. Median TTTS with Cal/BD foam was 6 weeks; this could not be determined for Cal/BD gel as 50% treatment success was not achieved (P < 0.001). Adverse drug reactions were reported in 14 (7.6%) Cal/BD aerosol foam patients and 7 (3.7%) Cal/BD gel patients; all were single events except for itch with Cal/BD aerosol foam (n = 5; 2.7%) and worsening psoriasis with Cal/BD gel (n = 3; 1.6%). Cal/BD aerosol foam showed significantly greater efficacy after 4 weeks, than 8 weeks of treatment with Cal/BD gel, with similar tolerability. © 2016 European Academy of Dermatology and Venereology.

Ostracode-based reconstruction from 23,300 to about 20,250 cal yr BP of climate, and paleohydrology of a groundwater-fed pond near St. Louis, Missouri

USGS Publications Warehouse

Curry, B.; Delorme, D.

2003-01-01

The water chemistry of a groundwater-fed sinkhole-pond near St. Louis, Missouri, and its associated climate during the last glaciation are reconstructed by comparison with autecological data of modern ostracodes from about 5,500 sites in Canada. A 4.8-m succession of fossiliferous sediment yielded ostracode assemblages that collectively are generally found today in ponds in North America including the species Cyclocypris ampla, C. laevis, Cypridopsis vidua, Candona crogmaniana, C. distincta, and C. ohioensis. Fossils of Picea needles and the ostracode Cyclocypris sharpei imply that best analog sites for the succession are in central to south-central Canada. The pond formed 23,300 ?? 400 cal yr BP when a sinkhole became plugged by a clay bed about 1 m thick. By about 20,250 cal yr BP, the pond had desiccated and was buried by loess. The sediment accumulation rate was about 0.18 cm/yr, and each sample interval (6 cm) represents a time slice of ???33 years. Data from this record provides the first fairly high resolution proxy record of the glacial paleoclimate of the mid-latitude of North America. The analog data indicate the water in the hydrologically-open spring-fed pond was less than 1 m deep. The paleoclimatic reconstructions imply gradually drier conditions and uniform, cool temperatures. The shallow water depth indicates that the temperature reconstruction is robust with mean annual temperatures (MATs) that ranged between 0.8 and 3.9??C, and mean July temperatures that ranged from 16.8 and 18.1??C. Other estimated climatic parameters include mean annual precipitation (MAP; 430 to 840 mm/yr), and moisture balance (P-E; -111 to 298 mm/yr). Compared to values measured today at St. Louis, the MAP was about 400 mm less, MAT about 10??C cooler, and P-E, about the same. These values are consistent with other published reconstructions based on modern analog analysis of fossil beetles and pollen, and paleothermometry based on amino acid racemization. The total dissolved

Holocene rainfall runoff in the central Ethiopian highlands and evolution of the River Nile drainage system as revealed from a sediment record from Lake Dendi

NASA Astrophysics Data System (ADS)

Wagner, Bernd; Wennrich, Volker; Viehberg, Finn; Junginger, Annett; Kolvenbach, Anne; Rethemeyer, Janet; Schaebitz, Frank; Schmiedl, Gerhard

2018-04-01

A 12 m long sediment sequence was recovered from the eastern Dendi Crater lake, located on the central Ethiopian Plateau and in the region of the Blue Nile headwaters. 24 AMS radiocarbon dates from bulk organic carbon samples indicate that the sediment sequence spans the last ca. 12 cal kyr BP. Sedimentological and geochemical data from the sediment sequence that were combined with initial diatom information show only moderate change in precipitation and catchment runoff during that period, probably due to the elevated location of the study region in the Ethiopian highlands. Less humid conditions prevailed during the Younger Dryas (YD). After the return to full humid conditions of the African Humid Period (AHP), a 2 m thick tephra layer, probably originating from an eruption of the Wenchi crater 12 km to the west of the lake, was deposited at 10.2 cal kyr BP. Subsequently, single thin horizons of high clastic matter imply that short spells of dry conditions and significantly increased rainfall, respectively, superimpose the generally humid conditions. The end of the AHP is rather gradual and precedes relatively stable and less humid conditions around 3.9 cal kyr BP. Subsequently, slightly increasing catchment runoff led to sediment redeposition, increasing nutrient supply, and highest trophic states in the lake until 1.5 cal kyr BP. A highly variable increase in clastic matter indicates fluctuating and increasing catchment runoff over the last 1500 years. The data from Lake Dendi show, in concert with other records from the Nile catchment and the Eastern Mediterranean Sea (EMS), that the Blue Nile discharge was relatively high between ca. 10.0 and 8.7 cal kyr BP. Subsequent aridification peaked with some regional differences between ca. 4.0 and 2.6 cal kyr BP. Higher discharge in the Blue Nile hydraulic regime after 2.6 cal kyr BP is probably triggered by more local increase in rainfall, which is tentatively caused by a change in the influence of the Indian Ocean

Structural Integrity of Proteins under Applied Bias during Solid-State Nanopore Translocation

NASA Astrophysics Data System (ADS)

Hasan, Mohammad R.; Khanzada, Raja Raheel; Mahmood, Mohammed A. I.; Ashfaq, Adnan; Iqbal, Samir M.

2015-03-01

The translocation behavior of proteins through solid-state nanopores can be used as a new way to detect and identify proteins. The ionic current through a nanopore that flows under applied bias gets perturbed when a biomolecule traverses the Nanopore. It is important for a protein detection scheme to know of any changes in the three-dimensional structure of the molecule during the process. Here we report the data on structural integrity of protein during translocation through nanopore under different applied biases. Nanoscale Molecular Dynamic was used to establish a framework to study the changes in protein structures as these travelled across the nanopore. The analysis revealed the contributions of structural changes of protein to its ionic current signature. As a model, thrombin protein crystalline structure was imported and positioned inside a 6 nm diameter pore in a 6 nm thick silicon nitride membrane. The protein was solvated in 1 M KCl at 295 K and the system was equilibrated for 20 ns to attain its minimum energy state. The simulation was performed at different electric fields from 0 to 1 kCal/(mol.Å.e). RMSD, radial distribution function, movement of the center of mass and velocity of the protein were calculated. The results showed linear increments in the velocity and perturbations in ionic current profile with increasing electric potential. Support Acknowledged from NSF through ECCS-1201878.

A cost-effectiveness analysis of calcipotriol plus betamethasone dipropionate aerosol foam versus gel for the topical treatment of plaque psoriasis.

PubMed

Foley, Peter; Garrett, Sinead; Ryttig, Lasse

2018-01-24

Calcipotriol 50 µg/g and betamethasone 0.5 mg/g dipropionate (Cal/BD) aerosol foam formulation provides greater effectiveness and improved patient preference compared with traditional Cal/BD formulations for the topical treatment of plaque psoriasis. To determine the cost-effectiveness of Cal/BD foam compared with Cal/BD gel from the Australian perspective. A Markov model was developed to evaluate the cost-effectiveness of topical Cal/BD foam and gel for the treatment of people with plaque psoriasis. Treatment effectiveness, safety, and utilities were based on a randomized control trial, resource use was informed by expert opinion, and unit costs were obtained from public sources. Outcomes were reported in terms of 1-year costs, quality-adjusted life years, and incremental cost-effectiveness ratios. All costs were reported in 2017 Australian Dollars. The model showed that patients using Cal/BD foam had more QALYs and higher costs over 1 year compared with patients using Cal/BD gel, resulting in a cost of $13,609 per QALY gained at 4-weeks. When 4 weeks of Cal/BD foam was compared with 8 weeks of Cal/BD gel treatment, Cal/BD foam was $8 less expensive and resulted in 0.006 more QALYs gained. Sensitivity analyses showed that, compared with Cal/BD ointment, Cal/BD foam was associated with an incremental cost of $15,091 per QALY gained. Cal/BD foam is the most cost-effective Cal/BD formulation for the topical treatment of patients with plaque psoriasis.

Two Sides of the Same Coin: Reaching Nontraditional Students

ERIC Educational Resources Information Center

Berg, Steven L.

2005-01-01

This paper presents interviews with Barbara Bonham, a Senior Researcher at the National Center for Developmental Education and a member of the faculty at the Kellogg Institute, Appalachian State University in Boone, North Carolina and Melanie Chu, the Outreach Librarian at Cal State San Marcos in San Marcos, California. In these interviews they…

Lysosomes and unfolded protein response, determinants of differential resistance of melanoma cells to vinca alkaloids.

PubMed

Vincent, Laure-Anais; Attaoua, Chaker; Bellis, Michel; Rozkydalova, Lucie; Hadj-Kaddour, Kamel; Vian, Laurence; Cuq, Pierre

2015-04-01

On account of its strong ability to become chemoresistant after a primary response to drugs, malignant melanoma (MM) remains a therapeutic challenge. This study focuses on acquired resistance to vinca alkaloids (VAs) using VA-resistant MM cell lines (CAL1R-VCR, CAL1R-VDS, and CAL1R-VRB), established by long-term continuous exposure of parental CAL1-wt cells to vincristine (VCR), vindesine (VDS), or vinorelbine (VRB), respectively. Transcriptomic profiling using rma and rdam methods led to distinguish two cell groups: CAL1R-VCR and CAL1R-VDS, CAL1R-VRB, and CAL1-wt. mgsa of the specifically altered genes in the first group evidenced the GO terms 'lysosomal lumen' and 'vacuolar lumen' linked to underexpressed genes, and 'endoplasmic reticulum (ER) stress response' associated with overexpressed genes. A specific reduction of lysosomal enzymes, independent of acidic vacuole organelle (AVO) turnover, was observed (LTG probe) in CAL1R-VCR and CAL1R-VDS cells. It was associated with the specific lowering of cathepsin B and L, known to be involved in the lysosomal pathway of apoptosis. Confirming gene profiling, the same groups (CAL1R-VCR and CAL1R-VDS, CAL1-wt and CAL1R-VRB) could be distinguished regarding the VA-mediated changes on mean size areas and on acidic compartment volumes. These two parameters were reduced in CAL1R-VCR and CAL1R-VDS cells, suggesting a smaller AVO accumulation and thus a reduced sensitivity to lysosomal membrane permeabilization-mediated apoptosis. In addition, 'ER stress response' inhibition by tauroursodeoxycholic acid induced a higher VA sensitization of the first cell group. In conclusion, lysosomes and unfolded protein response could be key determinants of the differential resistance of MM to VAs. © 2015 Société Française de Pharmacologie et de Thérapeutique.

Pharmacological characterization of receptor-activity-modifying proteins (RAMPs) and the human calcitonin receptor.

PubMed

Armour, S L; Foord, S; Kenakin, T; Chen, W J

1999-12-01

Receptor-activity-modifying proteins (RAMPs) are a family of single transmembrane domain proteins shown to be important for the transport and ligand specificity of the calcitonin gene-related peptide (CGRP) receptor. In this report, we describe the analysis of pharmacological properties of the human calcitonin receptor (hCTR) coexpressed with different RAMPs with the use of the Xenopus laevis melanophore expression system. We show that coexpression of RAMP3 with human calcitonin receptor changed the relative potency of hCTR to human calcitonin (hCAL) and rat amylin. RAMP1 and RAMP2, in contrast, had little effect on the change of hCTR potency to hCAL or rat amylin. When coexpressed with RAMP3, hCTR reversed the relative potency by a 3.5-fold loss in sensitivity to hCAL and a 19-fold increase in sensitivity to rat amylin. AC66, an inverse agonist, produced apparent simple competitive antagonism of hCAL and rat amylin, as indicated by linear Schild regressions. The potency of AC66 was changed in the blockade of rat amylin but not hCAL responses with RAMP3 coexpression. The mean pK(B) for AC66 to hCAL was 9.4 +/- 0.3 without RAMP3 and 9.45 +/- 0.07 with RAMP3. For the antagonism of AC66 to rat amylin, the pK(B) was 9.25 +/- 0.15 without RAMP3 and 8.2 +/- 0.35 with RAMP3. The finding suggests that RAMP3 might modify the active states of calcitonin receptor in such a way as to create a new receptor phenotype that is "amylin-like." Irrespective of the physiological association of the new receptor species, the finding that a coexpressed membrane protein can completely change agonist and antagonist affinities for a receptor raises implications for screening in recombinant receptor systems.

Active subsite properties, subsite residues and targeting to lysosomes or midgut lumen of cathepsins L from the beetle Tenebrio molitor.

PubMed

Damasceno, Ticiane F; Dias, Renata O; de Oliveira, Juliana R; Salinas, Roberto K; Juliano, Maria A; Ferreira, Clelia; Terra, Walter R

2017-10-01

Cathepsins L are the major digestive peptidases in the beetle Tenebrio molitor. Two digestive cathepsins L (TmCAL2 and TmCAL3) from it had their 3D structures solved. The aim of this paper was to study in details TmCAL3 specificity and properties and relate them to its 3D structure. Recombinant TmCAL3 was assayed with 64 oligopeptides with different amino acid replacements in positions P2, P1, P1' and P2'. Results showed that TmCAL3 S2 specificity differs from the human enzyme and that its specificities also explain why on autoactivation two propeptide residues remain in the enzyme. Data on free energy of binding and of activation showed that S1 and S2' are mainly involved in substrate binding, S1' acts in substrate binding and catalysis, whereas S2 is implied mainly in catalysis. Enzyme subsite residues were identified by docking with the same oligopeptide used for kinetics. The subsite hydrophobicities were calculated from the efficiency of hydrolysis of different amino acid replacements in the peptide and from docking data. The results were closer for S1 and S2' than for S1' and S2, indicating that the residue subsites that were more involved in transition state binding are different from those binding the substrate seen in docking. Besides TmCAL1-3, there are nine other cathepsins L, most of them more expressed at midgut. They are supposed to be directed to lysosomes by a Drosophila-like Lerp receptor and/or motifs in their prodomains. The mannose 6-phosphate lysosomal sorting machinery is absent from T. molitor transcriptome. Cathepsin L direction to midgut contents seems to depend on overexpression. Copyright © 2017 Elsevier Ltd. All rights reserved.

Great earthquakes of variable magnitude at the Cascadia subduction zone

USGS Publications Warehouse

Nelson, A.R.; Kelsey, H.M.; Witter, R.C.

2006-01-01

Comparison of histories of great earthquakes and accompanying tsunamis at eight coastal sites suggests plate-boundary ruptures of varying length, implying great earthquakes of variable magnitude at the Cascadia subduction zone. Inference of rupture length relies on degree of overlap on radiocarbon age ranges for earthquakes and tsunamis, and relative amounts of coseismic subsidence and heights of tsunamis. Written records of a tsunami in Japan provide the most conclusive evidence for rupture of much of the plate boundary during the earthquake of 26 January 1700. Cascadia stratigraphic evidence dating from about 1600??cal yr B.P., similar to that for the 1700 earthquake, implies a similarly long rupture with substantial subsidence and a high tsunami. Correlations are consistent with other long ruptures about 1350??cal yr B.P., 2500??cal yr B.P., 3400??cal yr B.P., 3800??cal yr B.P., 4400??cal yr B.P., and 4900??cal yr B.P. A rupture about 700-1100??cal yr B.P. was limited to the northern and central parts of the subduction zone, and a northern rupture about 2900??cal yr B.P. may have been similarly limited. Times of probable short ruptures in southern Cascadia include about 1100??cal yr B.P., 1700??cal yr B.P., 3200??cal yr B.P., 4200??cal yr B.P., 4600??cal yr B.P., and 4700??cal yr B.P. Rupture patterns suggest that the plate boundary in northern Cascadia usually breaks in long ruptures during the greatest earthquakes. Ruptures in southernmost Cascadia vary in length and recurrence intervals more than ruptures in northern Cascadia.

Design and validation of a computer-aided learning program to enhance students' ability to recognize lameness in the horse.

PubMed

Barstow, Amy; Pfau, Thilo; Bolt, David M; Smith, Roger K; Weller, Renate

2014-01-01

The ability to recognize lameness in the horse is an important skill for veterinary graduates; however, opportunities to develop this skill at the undergraduate level are limited. Computer-aided learning programs (CALs) have been successful in supplementing practical skills teaching. The aim of this study was to design and validate a CAL for the teaching of equine lameness recognition (CAL1). A control CAL was designed to simulate learning by experience (CAL2). Student volunteers were randomly assigned to either CAL and tested to establish their current ability to recognize lameness. Retesting occurred both immediately following exposure and 1 week later. At each test point, the number of correct responses for forelimb and hind limb cases was determined. Student confidence was assessed before and after CAL exposure, with previous opportunities to recognize lameness taken into account. Immediately following exposure, the number of correct responses was significantly higher for CAL1 than for CAL2, both overall and for forelimb cases but not for hind limb cases. After 1 week, the CAL1 group performed significantly better overall compared to the CAL2 group, with no significant difference between forelimb and hind limb cases. Student confidence and ability to recognize lameness were significantly improved following exposure to CAL1. When considered as one category, students in years 4 and 5 performed significantly better than year 3 students. Gender did not significantly affect performance. CAL1 could be used to supplement current lameness recognition opportunities. CAL1 is, however, limited in its ability to improve lameness recognition, especially in relation to hind limb lameness where it was unable to attain a significant difference from CAL2.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olfe, J.

California Cooperative Oceanic Fisheries Investigations (CalCOFI) performs research in the area of sampling physical, chemical, and biological variables in the California Current. The information received is stored in databases and gives a better understanding of the physics and chemistry of the California Current. Their effect on the food chain make it possible to view current oceanographic and biological conditions in the context of the long term. Measurements taken during 1994 and early 1995 on CalCOFI cruises have indicated a return to normal conditions after anomalous conditions that dominated the two preceding years. The data have permitted an increasingly prompt assessmentmore » of the state of the California Current system off southern California. This report also contains papers presented at the CalCOFI conference in 1994 regarding the 1991--92 El Nino and its impact on fisheries. In addition, individual scientific contributions are included which provide an additional understanding of the processes involved in the California Current.« less

The Egalitarianism of Honors at a Polytechnic University

ERIC Educational Resources Information Center

Coley, Soraya M.

2015-01-01

The Kellogg Honors College (KHC) is a distinctive community within Cal Poly Pomona (CPP), a public university in Southern California and one of twenty-three universities in the California State University (CSU) system. With over 22,000 students, CPP is the second-largest polytechnic university in the United States. The university's goal is to…

Finding Spirituality through Confrontation and Celebration of Asianness in the Classroom

ERIC Educational Resources Information Center

Hao, Richie Neil

2009-01-01

One September morning, the author woke as a teacher--an international teaching assistant (ITA), to be exact--at a California State University (Cal State). As a twenty-five-year-old teaching assistant, he had the opportunity to teach hybrid public speaking classes that were designed for the American Culture and Language Program (ACLP), which turned…

Low-energy electron-impact ionization of helium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schow, E.; Hazlett, K.; Childers, J. G.

2005-12-15

Normalized doubly differential cross sections for the electron-impact ionization of helium at low energies are presented. The data are taken at the incident electron energies of 26.3, 28.3, 30.3, 32.5, 34.3, 36.5, and 40.7 eV and for scattering angles of 10 deg. -130 deg. The measurements involve the use of the moveable target method developed at California State University Fullerton to accurately determine the continuum background in the energy-loss spectra. Normalization of experimental data is made on a relative scale to well-established experimental differential cross sections for excitation of the n=2 manifold of helium and then on an absolute scalemore » to the well-established total ionization cross sections of Shah et al. [J. Phys. B 21, 2751 (1988)]. Comparisons are made with available experimental data and the results of the convergent close-coupling theory.« less

Aerosol Impacts on California Winter Clouds and Precipitation during CalWater 2011: Local Pollution versus Long-Range Transported Dust

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fan, Jiwen; Leung, Lai-Yung R.; DeMott, Paul J.

2014-01-03

Mineral dust aerosols often observed over California in winter and spring, associated with long-range transport from Asia and Sahara, have been linked to enhanced precipitation based on observations. Local anthropogenic pollution, on the other hand, was shown in previous observational and modeling studies to reduce precipitation. Here we incorporate recent developments in ice nucleation parameterizations to link aerosols with ice crystal formation in a spectral-bin cloud microphysical model coupled with the Weather Research and Forecasting (WRF) model, to examine the relative and combined impacts of dust and local pollution particles on cloud properties and precipitation type and intensity. Simulations aremore » carried out for two cloud cases with contrasting meteorology and cloud dynamics that occurred on February 16 (FEB16) and March 02 (MAR02) from the CalWater 2011 field campaign. In both cases, observations show the presence of dust and biological particles in a relative pristine environment. The simulated cloud microphysical properties and precipitation show reasonable agreement with aircraft and surface measurements. Model sensitivity experiments indicate that in the pristine environment, the dust and biological aerosol layers increase the accumulated precipitation by 10-20% from the Central Valley to the Sierra Nevada Mountains for both FEB16 and MAR02 due to a ~40% increase in snow formation, validating the observational hypothesis. Model results show that local pollution increases precipitation over the windward slope of the mountains by few percent due to increased snow formation when dust is present but reduces precipitation by 5-8% if dust is removed on FEB16. The effects of local pollution on cloud microphysics and precipitation strongly depend on meteorology including the strength of the Sierra Barrier Jet, and cloud dynamics. This study further underscores the importance of the interactions between local pollution, dust, and environmental

Heterogeneous formation of nitryl chloride and its role as a nocturnal NOx reservoir species during CalNex-LA 2010

NASA Astrophysics Data System (ADS)

Mielke, L. H.; Stutz, J.; Tsai, C.; Hurlock, S. C.; Roberts, J. M.; Veres, P. R.; Froyd, K. D.; Hayes, P. L.; Cubison, M. J.; Jimenez, J. L.; Washenfelder, R. A.; Young, C. J.; Gilman, J. B.; de Gouw, J. A.; Flynn, J. H.; Grossberg, N.; Lefer, B. L.; Liu, J.; Weber, R. J.; Osthoff, H. D.

2013-09-01

nocturnal conversion of dinitrogen pentoxide (N2O5) to nitryl chloride (ClNO2) on chloride-containing aerosol can be a regionally important NOx (= NO + NO2) recycling and halogen activation pathway that affects oxidant photochemistry the following day. Here we present a comprehensive measurement data set acquired at Pasadena, California, during the CalNex-LA campaign 2010 that included measurements of odd nitrogen and its major components (NOy = NOx + NO3 + 2N2O5 + ClNO2 + HNO3 + HONO + peroxyacyl, alkyl, and aerosol nitrates) and aerosol size distribution and composition. Nitryl chloride was present during every night of the study (median mixing ratio at sunrise 800 pptv) and was usually a more significant nocturnal NOx and odd oxygen (Ox = O3 + NO2 + 3N2O5 + ClNO2) reservoir species than N2O5 (whose concentrations were calculated from its equilibrium with NO2 and NO3). At sunrise, ClNO2 accounted for 21% of NOz (=NOy - NOx), 4% of NOy, and 2.5% of Ox, respectively (median values). Kinetic parameters for the N2O5 to ClNO2 conversion were estimated by relating ClNO2 concentrations to their time-integrated heterogeneous production from N2O5 and were highly variable between nights. Production of ClNO2 required conversion of N2O5 on submicron aerosol with average yield (φ) and N2O5 reactive uptake probability (γ) of γφ = 0.008 (maximum 0.04), scaled with submicron aerosol chloride content, and was suppressed by aerosol organic matter and liquid water content. Not all of the observed variability of ClNO2 production efficiency could be rationalized using current literature parameterizations.

Determining the Equation of State (EoS) Parameters for Ballistic Gelatin

DTIC Science & Technology

2015-09-01

standard deviation. The specific heat measured at room temperature reported in (Winter 1975) is approximately 1.13 cal/g/°C (= 4.73 J /g/K). Fig. 4...Piatt 2010) Table 3 Specific heat capacity, average heat capacity, and standard deviation Temperature (°C) Cp [ J /(g·K)] Cp Cp Cp Average Cp...density amorphous ice and their implications on pressure induced amorphization. J Chem Physics. 2005;122:124710. Appleby-Thomas GJ, Hazell PJ

A Calibration of NICMOS Camera 2 for Low Count Rates

NASA Astrophysics Data System (ADS)

Rubin, D.; Aldering, G.; Amanullah, R.; Barbary, K.; Dawson, K. S.; Deustua, S.; Faccioli, L.; Fadeyev, V.; Fakhouri, H. K.; Fruchter, A. S.; Gladders, M. D.; de Jong, R. S.; Koekemoer, A.; Krechmer, E.; Lidman, C.; Meyers, J.; Nordin, J.; Perlmutter, S.; Ripoche, P.; Schlegel, D. J.; Spadafora, A.; Suzuki, N.

2015-05-01

SM2/NIC-7049, SM2/NIC-7152, CAL/NIC-7607, CAL/NIC-7691, CAL/NIC-7693, GO-7887, CAL/NIC-7902, CAL/NIC-7904, GO/DD-7941, SM3/NIC-8983, SM3/NIC-8986, GTO/ACS-9290, ENG/NIC-9324, CAL/NIC-9325, GO-9352, GO-9375, SNAP-9485, CAL/NIC-9639, GO-9717, GO-9834, GO-9856, CAL/NIC-9995, CAL/NIC-9997, GO-10189, GO-10258, CAL/NIC-10381, CAL/NIC-10454, GO-10496, CAL/NIC-10725, CAL/NIC-10726, GO-10886, CAL/NIC-11060, CAL/NIC-11061, GO-11135, GO-11143, GO-11202, CAL/NIC-11319, GO/DD-11359, SM4/WFC3-11439, SM4/WFC3-11451, GO-11557, GO-11591, GO-11600, GO/DD-11799, CAL/WFC3-11921, CAL/WFC3-11926, GO/DD-12051, GO-12061, GO-12062, GO-12177, CAL/WFC3-12333, CAL/WFC3-12334, CAL/WFC3-12341, GO-12443, GO-12444, GO-12445, CAL/WFC3-12698, CAL/WFC3-12699, GO-12874, CAL/WFC3-13088, and CAL/WFC3-13089.

Blood and War

PubMed Central

Hedley-Whyte, John; Milamed, Debra R

2010-01-01

SUMMARY In 1894 Ulsterman and pathologist Almroth Wright described the citation of blood. Twenty-one years later it was introduced into wartime and clinical practice. Harvard Medical School had a large part in providing Colonel Andrew Fullerton, later Professor of Surgery, Queen's Belfast, with the intellectual and practical help for the Allies to deploy blood on the post-Somme Western Front and in Salonika. The key investigators and clinicians were Americans and Canadians who with Fullerton and Wright instructed the Allies. The key enablers were two Harvard-trained surgeons surnamed Robertson—Oswald H. (“Robby”) and L. Bruce (no relation). Physician Roger I. Lee of Harvard, surgeon George W Crile of Cleveland, Peyton Rous of the Rockefeller Institute and Richard Lewisohn of Mount Sinai Hospital, both located in the Upper East Side of New York City, played key roles. By Armistice in 1918, indirect citrated nutrient-enhanced blood transfusion was widely used by the Allies. Geoffrey Keynes was taught the techniques of blood transfusion by Dr. Benjamin Harrison Alton of Harvard at a Casualty Clearing Station near Albert at the time of the Battle of Passchendaele. Professor “Robby” Robertson, DSO, Sir Geoffrey Keynes and Sir Thomas Houston established blood banking. PMID:22375087

Is there a relationship between periodontal disease and causes of death? A cross sectional study.

PubMed

Natto, Zuhair S; Aladmawy, Majdi; Alasqah, Mohammed; Papas, Athena

2015-01-01

The aim of this study was to evaluate whether there is any correlation between periodontal disease and mortality contributing factors, such as cardiovascular disease and diabetes mellitus in the elderly population. A dental evaluation was performed by a single examiner at Tufts University dental clinics for 284 patients. Periodontal assessments were performed by probing with a manual UNC-15 periodontal probe to measure pocket depth and clinical attachment level (CAL) at 6 sites. Causes of death abstracted from death certificate. Statistical analysis involved ANOVA, chi-square and multivariate logistic regression analysis. The demographics of the population sample indicated that, most were females (except for diabetes mellitus), white, married, completed 13 years of education and were 83 years old on average. CAL (continuous or dichotomous) and marital status attained statistical significance (p<0.05) in contingency table analysis (Chi-square for independence). Individuals with increased CAL were 2.16 times more likely (OR=2.16, 95% CI=1.47-3.17) to die due to CVD and this effect persisted even after control for age, marital status, gender, race, years of education (OR=2.03, 95% CI=1.35-3.03). CAL (continuous or dichotomous) was much higher among those who died due to diabetes mellitus or out of state of Massachusetts. However, these results were not statistically significant. The same pattern was observed with pocket depth (continuous or dichotomous), but these results were not statistically significant either. CAL seems to be more sensitive to chronic diseases than pocket depth. Among those conditions, cardiovascular disease has the strongest effect.

A Systematic Review of the Literature on Women’s Health, 2000-2010

DTIC Science & Technology

2015-03-30

51. Williamson DA, Martin PD, Allen HR, et al. Changes in food intake and body weight associated with basic combat training. Mil Med. 2002;167(3...Ursano RJ, McCarroll JE, Martin LT, Norwood AE, Fullerton CS. Spousal aggression by U.S. Army female soldiers toward employed and unemployed civilian...sexual assault victimization and perpetration in a Navy recruit sample. J Interpers Viol. 2008;23(11):1636-1653. 319. Rentz ED, Marshall SW, Martin SL

Stress and Performance A Review of the Literature and its Applicability to the Military

DTIC Science & Technology

2005-01-01

sense of ineffectiveness, and lack of accomplishment. Burnout is most often measured on the Maslach Burnout Inventory (MBI). The authors note that...single or to multiple stressors is burnout , defined by Maslach , Schaufeli, and Leiter (2001) to include exhaustion, feelings of cynicism and detachment, a...pp. 621-625. Maslach , C., W. Schaufeli, and M. Leiter, "Job Burnout ," Annual Review of Psychology, 2001. McCarroll, J., R. Ursano, and C. Fullerton

Manufacturing Methods and Technology for Digital Fault Isolation of Hybrid Microelectronic Assemblies.

DTIC Science & Technology

1982-03-01

Aircraft Company ARECAaSOENT CSR Ground Systems Group Task 007 Fullerton, California 92634 Project No. R1023 I$. =OTRS4.IWmOr SP NAnE lAD ABDASE it. REPORT...HMA feed mechanism, multiple type test sockets or adapters, and a localized UUT vessel for functional tests at temperature. The engineering model AP...test excluding (deactivated) microprocessor. * Models UUT and test adapter as a ROM. Independent latches or registers from interconnecting ports to

76 FR 54463 - Proposed Consent Decree, Clean Air Act Citizen Suit

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-01

... lawsuit filed by WildEarth Guardians and Sierra Club in the United States District Court for the Northern District of California: WildEarth Guardians et al. v. Jackson, No. 3:11-cv-00190-WHA (N.D. Cal.). On July 6...

Rhenium Complexes and Clusters Supported on c-Al2O3: Effects of Rhenium Oxidation State and Rhenium Cluster Size on Catalytic Activity for n-butane Hydrogenolysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lobo Lapidus, R.; Gates, B

2009-01-01

Supported metals prepared from H{sub 3}Re{sub 3}(CO){sub 12} on {gamma}-Al{sub 2}O{sub 3} were treated under conditions that led to various rhenium structures on the support and were tested as catalysts for n-butane conversion in the presence of H{sub 2} in a flow reactor at 533 K and 1 atm. After use, two samples were characterized by X-ray absorption edge positions of approximately 5.6 eV (relative to rhenium metal), indicating that the rhenium was cationic and essentially in the same average oxidation state in each. But the Re-Re coordination numbers found by extended X-ray absorption fine structure spectroscopy (2.2 and 5.1)more » show that the clusters in the two samples were significantly different in average nuclearity despite their indistinguishable rhenium oxidation states. Spectra of a third sample after catalysis indicate approximately Re{sub 3} clusters, on average, and an edge position of 4.5 eV. Thus, two samples contained clusters approximated as Re{sub 3} (on the basis of the Re-Re coordination number), on average, with different average rhenium oxidation states. The data allow resolution of the effects of rhenium oxidation state and cluster size, both of which affect the catalytic activity; larger clusters and a greater degree of reduction lead to increased activity.« less

Science and Technology to Support Fresh Water Availability in the United States

DTIC Science & Technology

2004-11-01

expand research and monitoring efforts to better understand the water cycle , its variability and relation to global climate change, and to provide basic...hydrologi- cal processes on the distribution, structure, and function of ecosys- tems, and on the effects of biotic processes on elements of the water ... cycle .”22 The science has evolved from one that simply indicated what minimum flows might be needed to maintain a particular spe- cies in a river, to

Interpretation of energy deposition data from historical operation of the transient test facility (TREAT)

DOE PAGES

DeHart, Mark D.; Baker, Benjamin A.; Ortensi, Javier

2017-07-27

The Transient Test Reactor (TREAT) at Idaho National Laboratory will resume operations in late 2017 after a 23 year hiatus while maintained in a cold standby state. Over that time period, computational power and simulation capabilities have increased substantially and now allow for new multiphysics modeling possibilities that were not practical or feasible for most of TREAT's operational history. Hence the return of TREAT to operational service provides a unique opportunity to apply state-of-the-art software and associated methods in the modeling and simulation of general three-dimensional steady state and kinetic behavior for reactor operation, and for coupling of the coremore » power transient model to experiment simulations. However, measurements taken in previous operations were intended to predict power deposition in experimental samples, with little consideration of three-dimensional core power distributions. Hence, interpretation of data for the purpose of validation of modern methods can be challenging. For the research discussed herein, efforts are described for the process of proper interpretation of data from the most recent calibration experiments performed in the core, the M8 calibration series (M8-CAL). These measurements were taken between 1990 and 1993 using a set of fission wires and test fuel pins to estimate the power deposition that would be produced in fast reactor test fuel pins during the M8 experiment series. Because of the decision to place TREAT into a standby state in 1994, the M8 series of transients were never performed. However, potentially valuable information relevant for validation is available in the M8-CAL measurement data, if properly interpreted. This article describes the current state of the process of recovery of useful data from M8-CAL measurements and quantification of biases and uncertainties to potentially apply to the validation of multiphysics methods.« less

Interpretation of energy deposition data from historical operation of the transient test facility (TREAT)

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeHart, Mark D.; Baker, Benjamin A.; Ortensi, Javier

The Transient Test Reactor (TREAT) at Idaho National Laboratory will resume operations in late 2017 after a 23 year hiatus while maintained in a cold standby state. Over that time period, computational power and simulation capabilities have increased substantially and now allow for new multiphysics modeling possibilities that were not practical or feasible for most of TREAT's operational history. Hence the return of TREAT to operational service provides a unique opportunity to apply state-of-the-art software and associated methods in the modeling and simulation of general three-dimensional steady state and kinetic behavior for reactor operation, and for coupling of the coremore » power transient model to experiment simulations. However, measurements taken in previous operations were intended to predict power deposition in experimental samples, with little consideration of three-dimensional core power distributions. Hence, interpretation of data for the purpose of validation of modern methods can be challenging. For the research discussed herein, efforts are described for the process of proper interpretation of data from the most recent calibration experiments performed in the core, the M8 calibration series (M8-CAL). These measurements were taken between 1990 and 1993 using a set of fission wires and test fuel pins to estimate the power deposition that would be produced in fast reactor test fuel pins during the M8 experiment series. Because of the decision to place TREAT into a standby state in 1994, the M8 series of transients were never performed. However, potentially valuable information relevant for validation is available in the M8-CAL measurement data, if properly interpreted. This article describes the current state of the process of recovery of useful data from M8-CAL measurements and quantification of biases and uncertainties to potentially apply to the validation of multiphysics methods.« less

Quantifying Atmospheric Mercury Emissions Sources in coastal California from Shipboard Measurements During CalNex 2010

NASA Astrophysics Data System (ADS)

Weiss-Penzias, P. S.; Lerner, B. M.; Williams, E. J.; Bates, T. S.; Gaston, C. J.; Prather, K. A.

2011-12-01

Mercury is a neurotoxin that can bioaccumulate in aquatic ecosystems to levels that are unsafe for humans and biota. It has both natural and anthropogenic sources to the atmosphere, where it can be transported and undergo transformations that lead to its deposition in both wet and dry forms. Due to recent surveys of mercury in fish in California that show widespread contamination, there is great interest in knowing the source of this mercury, whether it be from local, regional, or global emissions. In this study we made simultaneous measurements of gaseous elemental mercury (GEM), CO2, CO, NOx, SO2, O3, and meteorology during the spring of 2010 (May 14-June 8) on board the research vessel Atlantis during the CalNex campaign. The goal of this study was to observe and quantify emissions of GEM from known and potential sources along the California coast, including an incinerator, oil refineries, cargo ships, and natural ocean emissions. Additionally, an understanding of the behavior of GEM in the marine boundary layer under land-sea breeze conditions was sought. Our results indicate that on at least one occasion when the ship was located in the San Pedro harbor, emissions from an incinerator were observed, as indicated by high concentrations of GEM and unique single particle chemical composition. Using the ratio of the enhancements in GEM and CO and the CO emissions inventory for this facility, it was estimated that the annual GEM emissions were 11 +/- 5 kg. This is a factor of 5 lower than the reported total mercury emissions inventory for this facility in 2008. The discrepancy may be explained if a significant fraction of the emissions were gaseous oxidized and particulate mercury, since only GEM was measured. Additionally, a plume from a cargo ship was intercepted and the GEM/CO2 enhancement ratio indicated that approximately 13 tonnes of GEM are emitted from shipping worldwide, assuming values for global fuel usage and a CO2/fuel burned mass ratio. In spite of

Fabrication of Calix[4]arene Derivative Monolayers to Control Orientation of Antibody Immobilization

PubMed Central

Chen, Hongxia; Liu, Feng; Qi, Fangjie; Koh, Kwangnak; Wang, Keming

2014-01-01

Three calix[4]arene (Cal-4) derivatives which separately contain ethylester (1), carboxylic acid (2), and crownether (3) at the lower rim with a common reactive thiol at the upper rim were synthesized and constructed to self-assembled monolayers (SAMs) on Au films. After spectroscopic characterization of the monolayers, surface coverage and orientation of antibody immobilized on the Cal-4 derivative SAMs were studied by surface plasmon resonance (SPR) technique. Experimental results revealed that the antibody could be immobilized on the Cal-4 derivatives spontaneously. The orientation of absorbed antibody on the Cal-4 derivative SAMs is related to the SAM’s dipole moment. The possible orientations of the antibody immobilized on the Cal-4 derivative 1 SAM are lying-on or side-on, while on the Cal-4 derivative 2 and Cal-4 derivative 3 head-on and end-on respectively. These experimental results demonstrate the surface dipole moment of Cal-4 derivative appears to be an important factor to antibody orientation. Cal-4 derivatives are useful in developing site direct protein chips. PMID:24690993

78 FR 17727 - Self-Regulatory Organizations; International Securities Exchange, LLC; Order Approving Proposed...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-22

... and each Exchange Director's underlying business, ISE also stated that it believes that Exchange... Exchange to align its Board structure in accordance with corporate governance best practices guidelines... Services Proxy Voting Guidelines, the CalPERS Core Principles of Accountable Corporate Governance, the TIAA...

Heterogeneous reactivity of sea spray particles during the CalNex field campaign: Insight from single particle measurements and correlations with gas phase measurements

NASA Astrophysics Data System (ADS)

Gaston, C. J.; Riedel, T. P.; Thornton, J. A.; Wagner, N.; Brown, S. S.; Quinn, P.; Bates, T. S.; Prather, K. A.

2011-12-01

Sea spray particles are ubiquitous in marine environments. Heterogeneous reactions between sea spray particles and gas phase pollutants, such as HNO3(g), and N2O5(g), alter particle composition by displacing particulate phase halogens in sea spray and releasing these halogen species into the gas phase; these halogen-containing gas phase species play a significant role in tropospheric ozone production. Measurements of both gas phase and particle phase species on board the R/V Atlantis during the CalNEX 2010 field campaign provided an opportunity to examine the impact of heterogeneous reactivity of marine aerosols along the California coast. During the cruise, coastal measurements were made near the Santa Monica and Port of Los Angeles regions to monitor the chemical processing of marine aerosols. Sea spray particles were analyzed since these particles were the major chloride-containing particles detected. Real-time single particle measurements made using an aerosol time-of-flight mass spectrometer (ATOFMS) revealed the nocturnal processing of sea spray particles through the loss of particulate chloride and a simultaneous gain in particulate nitrate. Gas phase measurements are consistent with the particle phase observations: As N2O5(g) levels rose overnight, the production of ClNO2(g) coincided with the decrease in particulate chloride. These observations provide unique insight into heterogeneous reactivity from both a gas and particle phase perspective. Results from these measurements can be used to better constrain the rate of heterogeneous reactions on sea spray particles.

Fundamental Interactions for Atom Interferometry with Ultracold Quantum Gases in a Microgravity Environment

NASA Astrophysics Data System (ADS)

D'Incao, Jose P.; Willians, Jason R.

2015-05-01

Precision atom interferometers (AI) in space are a key element for several applications of interest to NASA. Our proposal for participating in the Cold Atom Laboratory (CAL) onboard the International Space Station is dedicated to mitigating the leading-order systematics expected to corrupt future high-precision AI-based measurements of fundamental physics in microgravity. One important focus of our proposal is to enhance initial state preparation for dual-species AIs. Our proposed filtering scheme uses Feshbach molecular states to create highly correlated mixtures of heteronuclear atomic gases in both their position and momentum distributions. We will detail our filtering scheme along with the main factors that determine its efficiency. We also show that the atomic and molecular heating and loss rates can be mitigated at the unique temperature and density regimes accessible on CAL. This research is supported by the National Aeronautics and Space Administration.

Installation Restoration Program Stage 3. Remedial Investigation/ Feasibility Study Elmendorf AFB, Alaska. Volume 2. Section 5 - Bibliography Text

DTIC Science & Technology

1990-05-01

ELME’IDORF AFB, AK UNITED STATES AIR FORCE OCCUPATIONAL & ENVIRONMENTAL HEALTH LABORATORY (AFSC) ilb(. IiCAL Sr.(VICES DIVISION (AFOEHLi £3) I BROOKS AIR...UNITED STATES AIR FORCE OCCUPATIONAL AND ENVIRONMENTAL HEALTH LABORATORY (AFSC) TECHNICAL SERVICES DIVISION (AFOEHL/TS) BROOKS AIR FORCE BASE, TEXAS...the following criteria: technical feasibility, institutional requirements, environmental impacts, public health impacts, and cost. This Alternative

Record of the North American southwest monsoon from Gulf of Mexico sediment cores

USGS Publications Warehouse

Poore, R.Z.; Pavich, M.J.; Grissino-Mayer, H. D.

2005-01-01

Summer monsoonal rains (the southwest monsoon) are an important source of moisture for parts of the southwestern United States and northern Mexico. Improved documentation of the variability in the southwest monsoon is needed because changes in the amount and seasonal distribution of precipitation in this semiarid region of North America influence overall water supply and fire severity. Comparison of abundance variations in the planktic foraminifer Globigerinoides sacculifer in marine cores from the western and northern Gulf of Mexico with terrestrial proxy records of precipitation (tree-ring width and packrat-midden occurrences) from the southwestern United States indicate that G. sacculifer abundance is a proxy for the southwest monsoon on millennial and submillennial time scales. The marine record confirms the presence of a severe multicentury drought centered ca. 1600 calendar (cal.) yr B.P. as well as several multidecadal droughts that have been identified in a long tree-ring record spanning the past 2000 cal. yr from westcentral New Mexico. The marine record further suggests that monsoon circulation, and thus summer rainfall, was enhanced in the middle Holocene (ca. 6500-4500 14C yr B.P.; ca. 6980-4710 cal. yr B.P.). The marine proxy provides the potential for constructing a highly resolved, well-dated, and continuous history of the southwest monsoon for the entire Holocene. ?? 2005 Geological Society of America.

Cell-assisted lipotransfer: Friend or foe in fat grafting? Systematic review and meta-analysis.

PubMed

Laloze, J; Varin, A; Gilhodes, J; Bertheuil, N; Grolleau, J L; Brie, J; Usseglio, J; Sensebe, L; Filleron, T; Chaput, B

2018-02-01

Autologous fat grafting is a common procedure for soft-tissue reconstruction but is associated with a graft resorption rate ranging from 20% to 80%. To improve the fat graft survival rate, a new technique, called cell-assisted lipotransfer (CAL), was developed. With CAL, fat is injected along with adipose-derived stromal cells that are assumed to improve fat survival rate. We conducted an evidence-based meta-analysis to evaluate the efficacy and safety of CAL as compared with conventional autologous fat grafting (non-CAL). The databases MEDLINE (via PubMed), Cochrane Library, EBSCO, Web of Science, and EMBASE were searched for reports of clinical trials, case series, and cohorts available from 2008 to 2016. We conducted a meta-analysis of the efficacy of CAL with data analysis concerning fat survival rate. The incidence of complications and the need for multiple procedures were evaluated to determine the safety of CAL. We identified 25 studies (696 patients) that were included in the systematic review; 16 studies were included in the meta-analysis to evaluate the efficacy of CAL. The fat survival rate was significantly higher with CAL than non-CAL (64% vs. 44%, p < .0001) independent of injection site (breast and face). This benefit of CAL was significant for only injection volumes <100 ml (p = .03). The two groups did not differ in frequency of multiple procedures after fat grafting, but the incidence of complications was greater with CAL than non-CAL (8.4% vs. 1.5%, p = .0019). The CAL method is associated with better fat survival rate than with conventional fat grafting but only for small volumes of fat grafting (<100 ml). Nonetheless, the new technique is associated with more complications and did not reduce the number of surgical procedures needed after the first fat grafting. More prospective studies are required to draw clinical conclusions and to demonstrate the real benefit of CAL as compared with common autologous fat grafting. Copyright © 2017

From Vision to Reality: 50 Years of Phased Array Development

DTIC Science & Technology

2016-09-30

This paper cites the most prominent U.S.-deployed phased array radars as viewed by one phased-array radar advocate. Key words: radar, antenna array...phased array, phased array radar, radar antennas , array I. INTRODUCTION I welcome the opportunity to talk with today’s phased array engineers and...their test site in Fullerton, CA in the mid-1960s and was impressed by the size of the antennas . Eight apertures were deployed on each ship to

Proceedings of the Annual Conference of the Military Testing Association Held in San Diego, California on 26-29 October 1992. Volume 2

DTIC Science & Technology

1992-10-29

Blend engine stator vane K 620 Inspect engines removed from storag G 253 Blend engine turbine air seals K 621 Inspect fuel manifold test stands * 254...Assessment and Human Learning Skills G. F Fullerton D. P. Hunt 497 How Personnel Testing is Adapting to a Changing Air Force T S. Ziebell 503 Problems of...of Intelligence Among Navy and Air Force Personnel R. F Dillon 526 Session 25 Measuring Martial Attitudes: The Military Ethos Scale (MES) in Retrcspect

EXPERIMENT - SHUTTLE

NASA Image and Video Library

1982-03-05

S82-27835 (26 Feb. 1982) --- The astronaut crew members for NASA?s third space transportation system (STS-3) flight meet with Todd E. Nelson, who devised a scientific experiment to fly on their mission. Astronauts Jack R. Lousma, left, commander, and C. Gordon Fullerton, pilot, along with the 18-year-old high school senior, discussed the experiment, entitled ?Insects in Flight Motion Study,? during a press briefing in JSC?s public affairs facility. Photo credit: NASA

EXPERIMENTS - SHUTTLE

NASA Image and Video Library

1982-03-01

S82-27604 (26 Feb. 1982) --- The astronaut crew members for NASA?s third space transportation system (STS-3) flight meet with Todd E. Nelson, who devised a scientific experiment to fly on their mission. Astronauts Jack R. Lousma, left, commander, and C. Gordon Fullerton, pilot, along with the 18-year-old high school senior, discussed the experiment, entitled ?Insects in Flight Motion Study,? during a press briefing in JSC?s public affairs facility. Photo credit: NASA

Theoretical studies of association and dissociation of Feshbach molecules in a microgravity environment

NASA Astrophysics Data System (ADS)

D'Incao, Jose; Williams, Jason

2017-04-01

NASA's Cold Atom Laboratory (CAL) is a multi-user facility scheduled for launch to the ISS in 2017. Our flight experiments with CAL will characterize and mitigate leading-order systematics in dual-atomic-species atom interferometers in microgravity relevant for future fundamental physics missions in space. As part of the initial state preparation for interferometry studies, here, we study the RF association and dissociation of weakly bound heteronuclear Feshbach molecules for expected parameters relevant for the microgravity environment of CAL. This includes temperatures on the pico-Kelvin range and atomic densities as low as 108/cm3. We show that under such conditions, thermal and loss effects can be greatly suppressed, resulting in high efficiency in both association and dissociation of extremely weakly bound Feshbach molecules and allowing for high accuracy determination coherent properties of such processes. In addition we study the possibility to implement delta-kick cooling techniques for weakly bound heteronuclear molecules and explore numerically other methods for molecular association and dissociation including the effects of three-body interactions. This research is supported by the National Aeronautics and Space Administration.

Reduced density and altered regulation of rat atrial L-type Ca2+ current in heart failure.

PubMed

Bond, Richard C; Bryant, Simon M; Watson, Judy J; Hancox, Jules C; Orchard, Clive H; James, Andrew F

2017-03-01

Constitutive regulation by PKA has recently been shown to contribute to L-type Ca 2+ current ( I CaL ) at the ventricular t-tubule in heart failure. Conversely, reduction in constitutive regulation by PKA has been proposed to underlie the downregulation of atrial I CaL in heart failure. The hypothesis that downregulation of atrial I CaL in heart failure involves reduced channel phosphorylation was examined. Anesthetized adult male Wistar rats underwent surgical coronary artery ligation (CAL, N =10) or equivalent sham-operation (Sham, N =12). Left atrial myocytes were isolated ~18 wk postsurgery and whole cell currents recorded (holding potential=-80 mV). I CaL activated by depolarizing pulses to voltages from -40 to +50 mV were normalized to cell capacitance and current density-voltage relations plotted. CAL cell capacitances were ~1.67-fold greater than Sham ( P ≤ 0.0001). Maximal I CaL conductance ( G max ) was downregulated more than 2-fold in CAL vs. Sham myocytes ( P < 0.0001). Norepinephrine (1 μmol/l) increased G max >50% more effectively in CAL than in Sham so that differences in I CaL density were abolished. Differences between CAL and Sham G max were not abolished by calyculin A (100 nmol/l), suggesting that increased protein dephosphorylation did not account for I CaL downregulation. Treatment with either H-89 (10 μmol/l) or AIP (5 μmol/l) had no effect on basal currents in Sham or CAL myocytes, indicating that, in contrast to ventricular myocytes, neither PKA nor CaMKII regulated basal I CaL Expression of the L-type α 1C -subunit, protein phosphatases 1 and 2A, and inhibitor-1 proteins was unchanged. In conclusion, reduction in PKA-dependent regulation did not contribute to downregulation of atrial I CaL in heart failure. NEW & NOTEWORTHY Whole cell recording of L-type Ca 2+ currents in atrial myocytes from rat hearts subjected to coronary artery ligation compared with those from sham-operated controls reveals marked reduction in current density

78 FR 24309 - California High-Speed Rail Authority-Construction Exemption-in Merced, Madera and Fresno Counties...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

...-Speed Rail Authority--Construction Exemption--in Merced, Madera and Fresno Counties, Cal On March 27, 2013, California High-Speed Rail Authority (Authority), a noncarrier state agency, filed a petition for... construct an approximately 65-mile dedicated high-speed passenger rail line between Merced and Fresno...

Teaching Neuroanatomy Using Computer-Aided Learning: What Makes for Successful Outcomes?

ERIC Educational Resources Information Center

Svirko, Elena; Mellanby, Jane

2017-01-01

Computer-aided learning (CAL) is an integral part of many medical courses. The neuroscience course at Oxford University for medical students includes CAL course of neuroanatomy. CAL is particularly suited to this since neuroanatomy requires much detailed three-dimensional visualization, which can be presented on screen. The CAL course was…

The impact of threshold language assistance programming on the accessibility of mental health services for persons with limited English proficiency in the Medi-Cal setting.

PubMed

McClellan, Sean R; Wu, Frances M; Snowden, Lonnie R

2012-06-01

Title VI of the 1964 Civil Rights Act prohibits federal funds recipients from providing care to limited English proficiency (LEP) persons more limited in scope or lower in quality than care provided to others. In 1999, the California Department of Mental Health implemented a "threshold language access policy" to meet its Title VI obligations. Under this policy, Medi-Cal agencies must provide language assistance programming in a non-English language where a county's Medical population contains either 3000 residents or 5% speakers of that language. We examine the impact of threshold language policy-required language assistance programming on LEP persons' access to mental health services by analyzing the county-level penetration rate of services for Russian, Spanish, and Vietnamese speakers across 34 California counties, over 10 years of quarterly data. Exploiting a time series with nonequivalent control group study design, we studied this phenomena using linear regression with random county effects to account for trends over time. Threshold language policy-required assistance programming led to an immediate and significant increase in the penetration rate of mental health services for Russian (8.2, P < 0.01) and Vietnamese (3.3, P < 0.01) language speaking persons. Threshold language assistance programming was effective in increasing mental health access for Russian and Vietnamese, but not for Spanish-speaking LEP persons.

Scale-invariant properties of public-debt growth

NASA Astrophysics Data System (ADS)

Petersen, A. M.; Podobnik, B.; Horvatic, D.; Stanley, H. E.

2010-05-01

Public debt is one of the important economic variables that quantitatively describes a nation's economy. Because bankruptcy is a risk faced even by institutions as large as governments (e.g., Iceland), national debt should be strictly controlled with respect to national wealth. Also, the problem of eliminating extreme poverty in the world is closely connected to the study of extremely poor debtor nations. We analyze the time evolution of national public debt and find "convergence": initially less-indebted countries increase their debt more quickly than initially more-indebted countries. We also analyze the public debt-to-GDP ratio {\\cal R} , a proxy for default risk, and approximate the probability density function P({\\cal R}) with a Gamma distribution, which can be used to establish thresholds for sustainable debt. We also observe "convergence" in {\\cal R} : countries with initially small {\\cal R} increase their {\\cal R} more quickly than countries with initially large {\\cal R} . The scaling relationships for debt and {\\cal R} have practical applications, e.g. the Maastricht Treaty requires members of the European Monetary Union to maintain {\\cal R} < 0.6 .

Evaluation of Wearable Simulation Interface for Military Training

DTIC Science & Technology

2012-01-01

Lampton, 2005). This assumption was based on support from the identi- cal elements theory (Holding, 1965; Thorndike & Woodworth, 1901), which states that...Annual Meeting of the Human Fac- tors and Ergonomics Society (pp. 2014–2018). Santa Monica, CA: Human Factors and Ergonomics Society. Thorndike , E. L

Modeling the diurnal variability of agricultural ammonia in Bakersfield, California, during the CalNex campaign

NASA Astrophysics Data System (ADS)

Lonsdale, Chantelle R.; Hegarty, Jennifer D.; Cady-Pereira, Karen E.; Alvarado, Matthew J.; Henze, Daven K.; Turner, Matthew D.; Capps, Shannon L.; Nowak, John B.; Neuman, J. Andy; Middlebrook, Ann M.; Bahreini, Roya; Murphy, Jennifer G.; Markovic, Milos Z.; VandenBoer, Trevor C.; Russell, Lynn M.; Scarino, Amy Jo

2017-02-01

NH3 retrievals from the NASA Tropospheric Emission Spectrometer (TES), as well as surface and aircraft observations of NH3(g) and submicron NH4(p), are used to evaluate modeled concentrations of NH3(g) and NH4(p) from the Community Multiscale Air Quality (CMAQ) model in the San Joaquin Valley (SJV) during the California Research at the Nexus of Air Quality and Climate Change (CalNex) campaign. We find that simulations of NH3 driven with the California Air Resources Board (CARB) emission inventory are qualitatively and spatially consistent with TES satellite observations, with a correlation coefficient (r2) of 0.64. However, the surface observations at Bakersfield indicate a diurnal cycle in the model bias, with CMAQ overestimating surface NH3 at night and underestimating it during the day. The surface, satellite, and aircraft observations all suggest that daytime NH3 emissions in the CARB inventory are underestimated by at least a factor of 2, while the nighttime overestimate of NH3(g) is likely due to a combination of overestimated NH3 emissions and underestimated deposition.Running CMAQ v5.0.2 with the bi-directional NH3 scheme reduces NH3 concentrations at night and increases them during the day. This reduces the model bias when compared to the surface and satellite observations, but the increased concentrations aloft significantly increase the bias relative to the aircraft observations. We attempt to further reduce model bias by using the surface observations at Bakersfield to derive an empirical diurnal cycle of NH3 emissions in the SJV, in which nighttime and midday emissions differ by about a factor of 4.5. Running CMAQv5.0.2 with a bi-directional NH3 scheme together with this emissions diurnal profile further reduces model bias relative to the surface observations. Comparison of these simulations with the vertical profile retrieved by TES shows little bias except for the lowest retrieved level, but the model bias relative to flight data aloft increases

Extension of the Expiration Date for State Disability Examiner Authority To Make Fully Favorable Quick Disability Determinations and Compassionate Allowance Determinations. Final rule.

PubMed

2016-10-24

We are extending, until December 28, 2018, the expiration date of our disability examiner authority (DEA) rule, which authorizes State agency disability examiners to make fully favorable determinations without the approval of a State agency medical or psychological consultant in claims that we consider under our quick disability determination (QDD) and compassionate allowance (CAL) processes. This is our last extension of this rule because we will phase out the use of DEA during the extension period under section 832 of the Bipartisan Budget Act of 2015 (BBA). This extension provides us the time necessary to take all of the administrative actions we need to take in order to reinstate uniform use of medical and psychological consultants. The current rule will expire on November 11, 2016. In this final rule, we are changing the November 11, 2016 expiration or "sunset" date to December 28, 2018, extending the authority for 2 years and 1 month. This is the final extension of our DEA rule. On December 28, 2018, at the conclusion of this extension, the authority for this test will terminate. We are making no other changes.

Effect of support flexibilty and damping on the dynamic response of a single mass flexible rotor in elastic bearings

NASA Technical Reports Server (NTRS)

Kirk, R. G.; Gunter, E. J.

1972-01-01

A steady state analysis of the shaft and the bearing housing motion was made by assuming synchronous precession of the system. The conditions under which the support system would act as a dynamic vibration absorber at the rotor critical speed were studied; plots of the rotor and support amplitudes, phase angles, and forces transmitted were evaluated by the computer, and the performance curves were automatically plotted by a CalComp plotter unit. Curves are presented on the optimization of the support housing characteristics to attenuate the rotor unbalance response over the entire rotor speed range. The complete transient motion including rotor unbalance was examined by integrating the equations of motion numerically using a modified fourth order Runge-Kutta procedure, and the resulting whirl orbits were plotted by the CalComp plotter unit. The results of the transient analysis are discussed with regards to the design optimization procedure derived from the steady-state analysis.

Integrated approach to colorectal anastomotic leakage: Communication, infection and healing disturbances

PubMed Central

Sparreboom, Cloë L; Wu, Zhou-Qiao; Ji, Jia-Fu; Lange, Johan F

2016-01-01

Colorectal anastomotic leakage (CAL) remains a major complication after colorectal surgery. Despite all efforts during the last decades, the incidence of CAL has not decreased. In this review, we summarize the available strategies regarding prevention, prediction and intervention of CAL and categorize them into three categories: communication, infection and healing disturbances. These three major factors actively interact during the onset of CAL. We aim to provide an integrated approach to CAL based on its etiology. The intraoperative air leak test, intraoperative endoscopy, radiological examinations and stoma construction mainly aim to detect and to prevent communication between the intra- and extra-luminal content. Other strategies including postoperative drainage, antibiotics, and infectious-parameter evaluation are intended to detect and prevent anastomotic or peritoneal infection. Most currently available interventions for CAL focus on the control of communication and infection, while strategies targeting the healing disturbances such as lifestyle changes, oxygen therapy and evaluation of metabolic biomarkers still lack wide clinical application. This simplified categorization may contribute to an integrated understanding of CAL. We strongly believe that this integrated approach should be taken into consideration during clinical practice. An integrated approach to CAL could contribute to a better understanding of the etiology of CAL and eventually better patient outcome. PMID:27621570

Impacts of using an ensemble Kalman filter on air quality simulations along the California-Mexico border region during Cal-Mex 2010 field campaign.

PubMed

Bei, Naifang; Li, Guohui; Meng, Zhiyong; Weng, Yonghui; Zavala, Miguel; Molina, L T

2014-11-15

The purpose of this study is to investigate the impact of using an ensemble Kalman filter (EnKF) on air quality simulations in the California-Mexico border region on two days (May 30 and June 04, 2010) during Cal-Mex 2010. The uncertainties in ozone (O3) and aerosol simulations in the border area due to the meteorological initial uncertainties were examined through ensemble simulations. The ensemble spread of surface O3 averaged over the coastal region was less than 10ppb. The spreads in the nitrate and ammonium aerosols are substantial on both days, mostly caused by the large uncertainties in the surface temperature and humidity simulations. In general, the forecast initialized with the EnKF analysis (EnKF) improved the simulation of meteorological fields to some degree in the border region compared to the reference forecast initialized with NCEP analysis data (FCST) and the simulation with observation nudging (FDDA), which in turn leading to reasonable air quality simulations. The simulated surface O3 distributions by EnKF were consistently better than FCST and FDDA on both days. EnKF usually produced more reasonable simulations of nitrate and ammonium aerosols compared to the observations, but still have difficulties in improving the simulations of organic and sulfate aerosols. However, discrepancies between the EnKF simulations and the measurements were still considerably large, particularly for sulfate and organic aerosols, indicating that there are still ample rooms for improvement in the present data assimilation and/or the modeling systems. Copyright © 2014 Elsevier B.V. All rights reserved.

Measurements of submicron aerosols at the California-Mexico border during the Cal-Mex 2010 field campaign

NASA Astrophysics Data System (ADS)

Levy, Misti E.; Zhang, Renyi; Zheng, Jun; Tan, Haobo; Wang, Yuan; Molina, Luisa T.; Takahama, S.; Russell, L. M.; Li, Guohui

2014-05-01

We present measurements of submicron aerosols in Tijuana, Mexico during the Cal-Mex 2010 field campaign. A suite of aerosol instrumentations were deployed, including a hygroscopic-volatility tandem differential mobility analyzer (HV-TDMA), aerosol particle mass analyzer (APM), condensation particle counter (CPC), cavity ring-down spectrometer (CRDS), and nephelometer to measure the aerosol size distributions, effective density, hygroscopic growth factors (HGF), volatility growth factors (VGF), and optical properties. The average mass concentration of PM0.6 is 10.39 ± 7.61 μg m-3, and the derived average black carbon (BC) mass concentration is 2.87 ± 2.65 μg m-3. There is little new particle formation or particle growth during the day, and the mass loading is dominated by organic aerosols and BC, which on average are 37% and 27% of PM1.0, respectively. For four particle sizes of 46, 81, 151, and 240 nm, the measured particle effective density, HGFs, and VGFs exhibit distinct diurnal trends and size-dependence. For smaller particles (46 and 81 nm), the effective density distribution is unimodal during the day and night, signifying an internally mixed aerosol composition. In contrast, larger particles (151 and 240 nm) exhibit a bi-modal effective density distribution during the daytime, indicating an external mixture of fresh BC and organic aerosols, but a unimodal distribution during the night, corresponding to an internal mixture of BC and organic aerosols. The smaller particles show a noticeable diurnal trend in the effective density distribution, with the highest effective density (1.70 g cm-3) occurring shortly after midnight and the lowest value (0.90 g cm-3) occurring during the afternoon, corresponding most likely to primary organic aerosols and BC, respectively. Both HGFs and VGFs measured are strongly size-dependent. HGFs increase with increasing particle size, indicating that the largest particles are more hygroscopic. VGFs decrease with increasing

Late Quaternary palaeoecological and palaeoclimatological reconstruction in the Gutaiului Mountains, northwest Romania

NASA Astrophysics Data System (ADS)

Feurdean, Angelica; Bennike, Ole

2004-12-01

Macrofossil, pollen, lithostratigraphy, mineral magnetic measurements (SIRM and magnetic susceptibility), loss-on-ignition, and AMS radiocarbon dating on sediments from two former crater lakes, situated at moderate altitudes in the Gutaiului Mountains of northwest Romania, allow reconstruction of Late Quaternary climate and environment. Shrubs and herbs with steppe and montane affinities along with stands of Betula and Pinus, colonised the surroundings of the sites prior to 14 700 cal. yr BP and the inferred climatic conditions were cold and dry. The gradual transition to open Pinus-Betula forests, slightly higher lake water temperatures, and higher lake productivity, indicate more stable environmental conditions between 14 700 and 14 100 cal. yr BP. This development was interrupted by cooler and drier climatic conditions between 14 100 and 13 800 cal. yr BP, as inferred from a reduction of open forests to patches, or stands, of Pinus, Betula, Larix, Salix and Populus. The expansion of a denser boreal forest, dominated by Picea, but including Pinus, Larix, Betula, Salix, and Ulmus started at 13 800 cal. yr BP, although the forest density seems to have been reduced between 13400 and 13200cal.yrBP. Air temperature and moisture availability gradually increased, but a change towards drier conditions is seen at 13400cal.yrBP. A distinct decrease in temperature and humidity between 12900 and 11500cal.yrBP led to a return of open vegetation, with patches of Betula, Larix, Salix, Pinus and Alnus and individuals of Picea. Macrofossils and pollen of aquatic plants indicate rising lake water temperatures and increased aquatic productivity already by ca. 11800cal.yrBP, 300 years earlier than documented by the terrestrial plant communities. At the onset of the Holocene, 11500cal.yrBP, forests dominated by Betula, Pinus and Larix expanded and were followed by dense Ulmus forests with Picea, Betula and Pinus at 11250cal.yrBP. Larix pollen was not found, but macrofossil evidence

third "free flight" of Shuttle Orbiter 101 Spacecraft

NASA Image and Video Library

1977-09-23

S77-28542 (23 Sept 1977) --- The shuttle Orbiter 101 "Enterprise" separates from the NASA 747 carrier aircraft during the third free flight of the Shuttle Approach and Landing Tests (ALT) conducted on September 23, 1977, at the Dryden Flight Research Center (DFRC) in Southern California. The vehicle, with astronauts Fred W. Haise Jr., commander, and C. Gordon Fullerton, pilot, remained in unpowered flight for five-minutes and 34-seconds before landing on the desert land of Edwards Air Force Base.

Detection and treatment rates for perinatal depression in a state Medicaid population.

PubMed

Geier, Michelle L; Hills, Nancy; Gonzales, Marco; Tum, Karoline; Finley, Patrick R

2015-02-01

The purpose of this investigation was to assess detection and treatment rates for perinatal depression among women enrolled in the California State Medicaid (Medi-Cal) program in comparison to female beneficiaries of reproductive age who did not give birth during the same study period. Investigators conducted a retrospective longitudinal cohort analysis of women between the ages of 18 and 39 years old who were continuously enrolled in the Medi-Cal fee-for-service program between January 2006 and December 2009. The perinatal cohort consisted of women with evidence of a live birth occurring between October 2007 and March 2009. The control cohort consisted of women in the same age group and health plan without evidence of pregnancy during this time frame. The primary outcome of this investigation was diagnosis of depression during 3 contiguous 9-month time frames: immediately prior to presumed conception, during pregnancy, and throughout the postpartum period. Secondary outcomes included within-group and cohort comparisons of treatment patterns (antidepressant or psychotherapy). A multivariable analysis of demographic factors predicting depression diagnosis or treatment was conducted as well. A total of 6030 women was identified in the perinatal cohort, and 56,709 women were included in the control group. The perinatal cohort was significantly less likely than nonpregnant controls to receive a diagnosis of depression both during pregnancy (prevalence=1.6% vs 3.5%; OR=0.45; 95% CI=0.35-0.55) and postpartum (2.2% vs 3.6%; OR=0.59; 95% CI=0.50-0.71). Similar differences were noted in antidepressant prescribing patterns apparent during these 2 time frames. A subgroup analysis of women who received a depression diagnosis revealed that only 48% of the perinatal cohort was provided any treatment during pregnancy (vs 72% of the control group; p<0.0001) or postpartum (57% vs 73%; p<0.0001). Specific demographic factors predicting a lower prevalence of depression detection or

Temporal and spatial patterns of Holocene dune activity on the Great Plains of North America: megadroughts and climate links

NASA Astrophysics Data System (ADS)

Forman, Steven L.; Oglesby, Robert; Webb, Robert S.

2001-05-01

The Holocene record of eolian sand and loess deposition is reviewed for numerous presently stabilized dune fields on the Great Plains of North America. Dune field activity reflects decade-to-century-scale dominance of drought that exceeded historic conditions, with a growing season deficit of precipitation >25%. The largest dune fields, the Nebraska Sand Hills and ergs in eastern Colorado, Kansas and the Southern High Plains showed peak activity sometime between ca. 7 and 5 cal. ka. Loess deposition between ca. 10 and 4 cal. ka also signifies widespread aridity. Most dune fields exhibit evidence for one or more reactivation events sometime in the past 2 cal. ka; a number of localities register two events post 1 cal. ka, the latest potentially after 1400 AD. However, there is not a clear association of the latest dune remobilization events with up to 13 droughts in the past 2 cal. ka identified in dendroclimatic and lacustrine records. Periods of persistent drought are associated with a La Niña-dominated climate state, with cooling of sea surface temperatures in the tropical Pacific Ocean and later of the tropical Atlantic Ocean and the Gulf of Mexico that significantly weakens cyclogenesis over central North America. As drought proceeds, reduced soil moisture and vegetation cover would lessen evaporative cooling and increase surface temperatures. These surface changes strengthen the eastward expansion of a high-pressure ridge aloft and shift the jet stream northward, further enhancing continent-wide drought. Uncertainty persists if dune fields will reactivate in the future at a scale similar to the Holocene because of widespread irrigation, the lack of migratory bison herds, and the suppression of prairie fires, all of which enhance stabilization of dune fields in the Great Plains.

Building a Better Web Site: A Practical Guide to Interactivity for Libraries.

ERIC Educational Resources Information Center

Braun, Linda W.

1998-01-01

Describes selected commercial and academic Web sites providing interactive services (Amazon; Jones Library, Amherst, MA; Pine Crest Lower School, Ft. Lauderdale, FL; Barnes & Noble; Cal State's Information Literacy Tutorials; PBS's techknow site; K.I.D.S. Report), and argues that libraries that stop at links and policy statements miss…

Evaluating the Effectiveness of E-Learning in Teacher Preparation

ERIC Educational Resources Information Center

Chiero, Robin; Beare, Paul; Marshall, James; Torgerson, Colleen

2015-01-01

Teacher education struggles with the challenge of preparing and retaining high-quality teachers who can work effectively with all students. While educator preparation is a strong correlate of student achievement, traditional university-based programmes are not available to all potential teachers. This manuscript describes CalStateTEACH, an online…

Assessing Cat Flea Microbiomes in Northern and Southern California by 16S rRNA Next-Generation Sequencing.

PubMed

Vasconcelos, Elton J R; Billeter, Sarah A; Jett, Lindsey A; Meinersmann, Richard J; Barr, Margaret C; Diniz, Pedro P V P; Oakley, Brian B

2018-06-12

Flea-borne diseases (FBDs) impact both human and animal health worldwide. Because adult fleas are obligately hematophagous and can harbor potential pathogens, fleas act as ectoparasites of vertebrates, as well as zoonotic disease vectors. Cat fleas (Ctenocephalides felis) are important vectors of two zoonotic bacterial genera listed as priority pathogens by the National Institute of Allergy and Infectious Diseases (NIAID-USA): Bartonella spp. and Rickettsia spp., causative agents of bartonelloses and rickettsioses, respectively. In this study, we introduce the first microbiome analysis of C. felis samples from California, determining the presence and abundance of relevant pathogenic genera by characterizing the cat flea microbiome through 16S rRNA next-generation sequencing (16S-NGS). Samples from both northern (NoCal) and southern (SoCal) California were assessed to expand current knowledge regarding FBDs in the state. We identified Rickettsia and Bartonella, as well as the endosymbiont Wolbachia, as the most abundant genera, followed by less abundant taxa. In comparison to our previous study screening Californian cat fleas for rickettsiae using PCR/digestion/sequencing of the ompB gene, the 16S-NGS approach applied herein showed a 95% level of agreement in detecting Rickettsia spp. There was no overall difference in microbiome diversity between NoCal and SoCal samples. Bacterial taxa identified by 16S-NGS in this study may help to improve epidemiological investigations, pathogen surveillance efforts, and clinical diagnostics of FBDs in California and elsewhere.

United States Air Force Summer Research Program -- 1993. Volume 9. Rome Laboratory

DTIC Science & Technology

1993-12-01

Walter Field: Electrical Engineering MS Laboratory: RL/IR Electrical Engineering University of Maine Vol-Page No: 9- 9 Orono, ME 4469-0000 Swindal, J...0000 Tipton, Kevin Field: Zoology MS Laboratory: AL/CF Nutrition and Food Scienc Auburn University Vol-Page No: 7-11 Auburn, AL 36849-5605 Tornow ...deterministic analysis assumed only 1-17 one handling. w ~vA-A-, PPIMAJý PATH Legen(3ND P"ysCaI LinK (forwarid VPC P’ýs Cal L-,* (reverse VPC) Figure 8. OPNET

Kinetic study of Candida antarctica lipase B immobilization using poly(methyl methacrylate) nanoparticles obtained by miniemulsion polymerization as support.

PubMed

Valério, Alexsandra; Nicoletti, Gabrieli; Cipolatti, Eliane P; Ninow, Jorge L; Araújo, Pedro H H; Sayer, Cláudia; de Oliveira, Débora

2015-03-01

With the objective to obtain immobilized Candida antarctica lipase B (CalB) with good activity and improved utilization rate, this study evaluated the influence of enzyme and crodamol concentrations and initiator type on the CalB enzyme immobilization in nanoparticles consisting of poly(methyl methacrylate) (PMMA) obtained by miniemulsion polymerization. The kinetic study of immobilized CalB enzyme in PMMA nanoparticles was evaluated in terms of monomer conversion, particle size, zeta potential, and relative activity. The optimum immobilization condition for CalB was compared with free enzyme in the p-NPL hydrolysis activity measurement. Results showed a higher CalB enzyme stability after 20 hydrolysis cycles compared with free CalB enzyme; in particular, the relative immobilized enzyme activity was maintained up to 40%. In conclusion, PMMA nanoparticles proved to be a good support for the CalB enzyme immobilization and may be used as a feasible alternative catalyst in industrial processes.

M1 Abrams Tank Procedure Guides

DTIC Science & Technology

1982-07-01

Vemp =. ... . Mheek mustlam- sitlee no"Ageper- 2. Cal.5 . . swetgh: (PAge LI) 3. CaLS . ... Zen (pag 13) BOUzSzMT M CAL. SO I.. Teak peatima. .. lafel...Cleee ,-. 13.~~ .eds a." . .ege ..... abeW "d us (P P U) :. -z KINK CAL. 50 3. vempe " .. ... .led (pg ) 2. o . .. .ad tio"ge mgety .. 1 4. IC omee .C.1

Conference in Rhetorical Criticism: Commended Papers (6th, Hayward, California, May 1, 1971).

ERIC Educational Resources Information Center

Peat, Stephen D., Ed.; And Others

At the sixth annual Cal-State Hayward Conference in Rhetorical Criticism, upper division and graduate students from 11 western colleges and universities presented papers on the theory, history, and criticism of rhetoric. Panels of faculty members from the same colleges and universities selected the three best papers for commendation and…

Conference in Rhetorical Criticism: Commended Papers, 1970 (5th, Hayward, California, May 9, 1970).

ERIC Educational Resources Information Center

Rose, Doreen K. F., Ed.; And Others

At the fifth annual Cal-State Hayward Conference in Rhetorical Criticism, upper division and graduate students from 14 western colleges and universities presented papers on the theory, history, and criticism of rhetoric. Panels of faculty members from the same colleges and universities selected the three best papers for commendation and…

Rock-magnetic proxies of wind intensity and dust since 51,200 cal BP from lacustrine sediments of Laguna Potrok Aike, southeastern Patagonia

NASA Astrophysics Data System (ADS)

Lisé-Pronovost, Agathe; St-Onge, Guillaume; Gogorza, Claudia; Haberzettl, Torsten; Jouve, Guillaume; Francus, Pierre; Ohlendorf, Christian; Gebhardt, Catalina; Zolitschka, Bernd

2015-02-01

The sedimentary archive from Laguna Potrok Aike is the only continuous record reaching back to the last Glacial period in continental southeastern Patagonia. Located in the path of the Southern Hemisphere westerly winds and in the source region of dust deposited in Antarctica during Glacial periods, southern Patagonia is a vantage point to reconstruct past changes in aeolian activity. Here we use high-resolution rock-magnetic and physical grain size data from site 2 of the International Continental scientific Drilling Program (ICDP) Potrok Aike maar lake Sediment Archive Drilling prOject (PASADO) in order to develop magnetic proxies of dust and wind intensity at 52°S since 51,200 cal BP. Rock-magnetic analysis indicates the magnetic mineral assemblage is dominated by detrital magnetite. Based on the estimated flux of magnetite to the lake and comparison with distal dust records from the Southern Ocean and Antarctica, kLF is interpreted as a dust indicator in the dust source of southern Patagonia at the millennial time scale, when ferrimagnetic grain size and coercivity influence are minimal. Comparison to physical grain-size data indicates that the median destructive field of isothermal remanent magnetization (MDFIRM) mostly reflects medium to coarse magnetite bearing silts typically transported by winds for short-term suspension. Comparison with wind-intensity proxies from the Southern Hemisphere during the last Glacial period and with regional records from Patagonia since the last deglaciation including marine, lacustrine and peat bog sediments as well as speleothems reveals similar variability with MDFIRM up to the centennial time scale. MDFIRM is interpreted as a wind-intensity proxy independent of moisture changes for southeastern Patagonia, with stronger winds capable of transporting coarser magnetite bearing silts to the lake.

The Cell Cycle Timing of Centromeric Chromatin Assembly in Drosophila Meiosis Is Distinct from Mitosis Yet Requires CAL1 and CENP-C

PubMed Central

Gorgescu, Walter; Tang, Jonathan; Costes, Sylvain V.; Karpen, Gary H.

2012-01-01

CENP-A (CID in flies) is the histone H3 variant essential for centromere specification, kinetochore formation, and chromosome segregation during cell division. Recent studies have elucidated major cell cycle mechanisms and factors critical for CENP-A incorporation in mitosis, predominantly in cultured cells. However, we do not understand the roles, regulation, and cell cycle timing of CENP-A assembly in somatic tissues in multicellular organisms and in meiosis, the specialized cell division cycle that gives rise to haploid gametes. Here we investigate the timing and requirements for CID assembly in mitotic tissues and male and female meiosis in Drosophila melanogaster, using fixed and live imaging combined with genetic approaches. We find that CID assembly initiates at late telophase and continues during G1 phase in somatic tissues in the organism, later than the metaphase assembly observed in cultured cells. Furthermore, CID assembly occurs at two distinct cell cycle phases during male meiosis: prophase of meiosis I and after exit from meiosis II, in spermatids. CID assembly in prophase I is also conserved in female meiosis. Interestingly, we observe a novel decrease in CID levels after the end of meiosis I and before meiosis II, which correlates temporally with changes in kinetochore organization and orientation. We also demonstrate that CID is retained on mature sperm despite the gross chromatin remodeling that occurs during protamine exchange. Finally, we show that the centromere proteins CAL1 and CENP-C are both required for CID assembly in meiosis and normal progression through spermatogenesis. We conclude that the cell cycle timing of CID assembly in meiosis is different from mitosis and that the efficient propagation of CID through meiotic divisions and on sperm is likely to be important for centromere specification in the developing zygote. PMID:23300382

Marine04 Marine radiocarbon age calibration, 26 ? 0 ka BP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hughen, K; Baille, M; Bard, E

2004-11-01

New radiocarbon calibration curves, IntCal04 and Marine04, have been constructed and internationally ratified to replace the terrestrial and marine components of IntCal98. The new calibration datasets extend an additional 2000 years, from 0-26 ka cal BP (Before Present, 0 cal BP = AD 1950), and provide much higher resolution, greater precision and more detailed structure than IntCal98. For the Marine04 curve, dendrochronologically dated tree-ring samples, converted with a box-diffusion model to marine mixed-layer ages, cover the period from 0-10.5 ka cal BP. Beyond 10.5 ka cal BP, high-resolution marine data become available from foraminifera in varved sediments and U/Th-dated corals.more » The marine records are corrected with site-specific {sup 14}C reservoir age information to provide a single global marine mixed-layer calibration from 10.5-26.0 ka cal BP. A substantial enhancement relative to IntCal98 is the introduction of a random walk model, which takes into account the uncertainty in both the calendar age and the radiocarbon age to calculate the underlying calibration curve. The marine datasets and calibration curve for marine samples from the surface mixed layer (Marine04) are discussed here. The tree-ring datasets, sources of uncertainty, and regional offsets are presented in detail in a companion paper by Reimer et al.« less

Variability in attachment of the coracoacromial ligament in relation with its morphology.

PubMed

Alraddadi, Abdulrahman; Alashkham, Abduelmenem; Lamb, Clare; Soames, Roger

2017-12-01

The coracoacromial ligament (CAL) presents with variable morphology and plays a significant role in the development of subacromial impingement syndrome. Sectioning the CAL has been suggested to relieve impingement of the rotator cuff. The aim of the current study was to investigate the CAL attachment in relation with ligament morphology. The CAL was investigated in 220 cadaveric shoulders from 58 males and 59 females, with a median age of 82 years (range 53-102 years). CALs were classified according to three factors: (1) number of bands present; (2) shape; and (3) attachment to the acromial and coracoid processes. 35 (16%) CALs had a single band, 84 (38%) two bands, and 101 (46%) three or more bands. CAL shape was either broadband (14: 6%), quadrangular (21: 10%), Y-shaped (84: 38%), or multiple-banded (101: 46%). More ligaments were attached to the medial aspect of the acromion (60%) and medial end of the coracoid (75%) than those restricted to the anterior edge of the acromion (40%) and posterior aspect of the coracoid (25%). Multiple-banded ligaments attached significantly more medially at the acromion and coracoid processes, while single band ligament attachments were restricted to the anterior edge of the acromion and posterior aspect of the coracoid process. The CAL has variable morphology and attachments with interconnections to different structures around the shoulder. CALs with a medial acromial attachment may narrow the subacromial space leading to further shoulder impingement.

Purification of legumin-like proteins from Coffea arabica and Coffea racemosa seeds and their insecticidal properties toward cowpea weevil ( Callosobruchus maculatus ) (Coleoptera: Bruchidae).

PubMed

Coelho, Mirela Batista; Macedo, Maria Lígia Rodrigues; Marangoni, Sérgio; Silva, Desiree Soares da; Cesarino, Igor; Mazzafera, Paulo

2010-03-10

Legumin-like proteins from seeds of Coffea arabica (CaL-1 and CaL-2) and Coffea racemosa (CrL-1 and CrL-2) were characterized and isolated by gel filtration and reverse-phase chromatography. The insecticidal properties of the purified proteins were tested against Callosobruchus maculatus using artificial diets. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analyses indicated that CaL-1 is composed of two subunits of 33 and 24 kDa, while CaL-2, CrL-1, and CrL-2 were monomeric with a single band of 14 kDa. The LD(50) values were 0.5% (w/w) for CaL-1 and 0.3% (w/w) for CaL-2, CrL-1, and CrL-2. ED(50) at 0.3% was assessed for all protein concentrations. The legumin-like proteins were not digested by midgut homogenates of C. maculatus until 8 h of incubation. CaL-1 and CaL-2 ( C. arabica ) and CrL-1 and CrL-2 ( C. racemosa ) are chitin-binding proteins, and their insecticidal properties toward C. maculatus larvae might be related to their capacity to bind chitin present in the larval gut and their associated low digestibility.

Case Studies in CAL!

ERIC Educational Resources Information Center

Rogers, David F., Ed.; Smith, P. R., Ed.

1984-01-01

Ten papers focus on applications in specific curriculum areas, modelling and simulation, and computer managed learning. Projects described include voice support for the visually handicapped, distance education, and industrial training, as well as teaching applied mathematics, several facets of engineering, zoology, and, with videodisc, observation…

CALS Test Network Handbook

DTIC Science & Technology

1993-03-01

Ltd Gillette Company Dorset, England Boston MA Foreign Broadcast Information Set. Giordano Associates Inc Frederick MD Long Branch NJ Formtek Inc...Associates Orem UT College Park MD InfoDesign Corp Johns Hopkins University Toronto, Ontario Laurel MD Information Spectrum Inc Joint Committee on Printing...Inc Washington DC Bel Air MD Navy Naval Research Laboratory OutSource Inc Washington DC Los Angeles CA 22 i +’ . S.. . -- -,•w• -- w,,Wmwmm mm -- m mmm

CalRecycle Home Page

Science.gov Websites

; Regulations Data Central Facility Information Toolbox (FacIT) Resources Grant, Payment, & Loan Programs environment--particularly in disadvantaged communities. See our Greenhouse Gas Reduction Grant and Loan

Conference in Rhetorical Criticism: Address of the Conference and Commended Papers (2nd, Hayward, Calif., May 1967).

ERIC Educational Resources Information Center

Barrett, Harold, Ed.; And Others

At the second annual Cal-State Hayward Conference in Rhetorical Criticism, upper division and graduate students from 17 colleges and universities presented papers on the theory, history, and criticism of rhetoric. Panels of faculty members from the same colleges and universities, serving as editor-critics, judged the six papers in this volume as…

Training Concerns for an Online Public Access Catalog.

ERIC Educational Resources Information Center

Rockman, Ilene F.; Adalian, Paul T., Jr.

This report is designed to raise issues and concerns which will affect the successful implementation of an education and training program once an online public access catalog (OLPAC) has been installed in the Kennedy Library at California Polytechnic State University (Cal Poly), San Luis Obispo. Information presented in the document was gathered…

Late quaternary changes in lakes, vegetation, and climate in the Bonneville Basin reconstructed from sediment cores from Great Salt Lake: Chapter 11

USGS Publications Warehouse

Thompson, Robert S.; Oviatt, Charles G.; Honke, Jeffrey S.; McGeehin, John

2016-01-01

Sediment cores from Great Salt Lake (GSL) provide the basis for reconstructing changes in lakes, vegetation, and climate for the last ~ 40 cal ka. Initially, the coring site was covered by a shallow saline lake and surrounded by Artemisia steppe or steppe-tundra under a cold and dry climate. As Lake Bonneville began to rise (from ~ 30 to 28 cal ka), Pinus and subalpine conifer pollen percentages increased and Artemisia declined, suggesting the onset of wetter conditions. Lake Bonneville oscillated near the Stansbury shoreline between ~ 26 and ~ 24 cal ka, rose to the Bonneville shoreline by ~ 18 cal ka, and then fell to the Provo shoreline, which it occupied until ~ 15 cal ka. Vegetation changed during this time span, albeit not always with the same direction or amplitude as the lake. The pollen percentages of Pinus and subalpine conifers were high from ~ 25 to 21.5 cal ka, indicating cool and moist conditions during the Stansbury oscillation and for much of the rise toward the Bonneville shoreline. Pinus percentages then decreased and Artemisia became codominant, suggesting drier and perhaps colder conditions from ~ 21 to ~ 15 cal ka, when Lake Bonneville was at or near its highest levels.Lake Bonneville declined to a low level by ~ 13 cal ka, while Pinus pollen percentages increased, indicating that conditions remained cooler and moister than today. During the Younger Dryas interval, the brief Gilbert episode rise in lake level was followed by a shallow lake with a stratified water column. This lake rise occurred as Pinus pollen percentages were declining and those of Artemisia were rising (reflecting increasingly dry conditions), after which Artemisia pollen was at very high levels (suggesting cold and dry conditions) for a brief period.Since ~ 10.6 cal ka lacustrine conditions have resembled those of present-day GSL. Pollen spectra for the period from ~ 10.6 to 7.2 cal ka have low levels of conifer pollen and high (for the

Crabs in a bucket: the politics of health care reform in California.

PubMed

Bergthold, L

1984-01-01

In 1982 the state of California adopted a package of legislation collectively known as "the Medi-Cal reform." This article examines the background of this reform, the process through which it was adopted by the state legislature, and its effects on the various interests involved. In particular, the article focuses on the alteration of power relationships occasioned by the emergence of business interests as an active force in the formulation of health policy.

Olfactory Response and Host Plant Feeding of the Central American Locust Schistocerca piceifrons piceifrons Walker to Common Plants in a Gregarious Zone.

PubMed

Poot-Pech, M A; Ruiz-Sánchez, E; Ballina-Gómez, H S; Gamboa-Angulo, M M; Reyes-Ramírez, A

2016-08-01

The Central American locust (CAL) Schistocerca piceifrons piceifrons Walker is one of the most harmful plant pests in the Yucatan Peninsula, where an important gregarious zone is located. The olfactory response and host plant acceptance by the CAL have not been studied in detail thus far. In this work, the olfactory response of the CAL to odor of various plant species was evaluated using an olfactometer test system. In addition, the host plant acceptance was assessed by the consumption of leaf area. Results showed that the CAL was highly attracted to odor of Pisonia aculeata. Evaluation of host plant acceptance showed that the CAL fed on Leucaena glauca and Waltheria americana, but not on P. aculeata or Guazuma ulmifolia. Analysis of leaf thickness, and leaf content of nitrogen (N) and carbon (C) showed that the CAL was attracted to plant species with low leaf C content.

Computational approach for designing thermostable Candida antarctica lipase B by molecular dynamics simulation.

PubMed

Park, Hyun June; Park, Kyungmoon; Kim, Yong Hwan; Yoo, Young Je

2014-12-20

Candida antarctica lipase B (CalB) is one of the most useful enzyme for various reactions and bioconversions. Enhancing thermostability of CalB is required for industrial applications. In this study, we propose a computational design strategy to improve the thermostability of CalB. Molecular dynamics simulations at various temperatures were used to investigate the common fluctuation sites in CalB, which are considered to be thermally weak points. The RosettaDesign algorithm was used to design the selected residues. The redesigned CalB was simulated to verify both the enhancement of intramolecular interactions and the lowering of the overall root-mean-square deviation (RMSD) values. The A251E mutant designed using this strategy showed a 2.5-fold higher thermostability than the wild-type CalB. This strategy could apply to other industry applicable enzymes. Copyright © 2014 Elsevier B.V. All rights reserved.

Teaching neuroanatomy using computer-aided learning: What makes for successful outcomes?

PubMed

Svirko, Elena; Mellanby, Jane

2017-11-01

Computer-aided learning (CAL) is an integral part of many medical courses. The neuroscience course at Oxford University for medical students includes CAL course of neuroanatomy. CAL is particularly suited to this since neuroanatomy requires much detailed three-dimensional visualization, which can be presented on screen. The CAL course was evaluated using the concept of approach to learning. The aims of university teaching are congruent with the deep approach-seeking meaning and relating new information to previous knowledge-rather than to the surface approach of concentrating on rote learning of detail. Seven cohorts of medical students (N = 869) filled in approach to learning scale and a questionnaire investigating their engagement with the CAL course. The students' scores on CAL-course-based neuroanatomy assessment and later university examinations were obtained. Although the students reported less use of the deep approach for the neuroanatomy CAL course than for the rest of their neuroanatomy course (mean = 24.99 vs. 31.49, P < 0.001), deep approach for CAL was positively correlated with neuroanatomy assessment performance (r = 0.12, P < 0.001). Time spent on the CAL course, enjoyment of it, the amount of CAL videos watched and quizzes completed were each significantly positively related to deep approach. The relationship between deep approach and enjoyment was particularly notable (25.5% shared variance). Reported relationships between deep approach and academic performance support the desirability of deep approach in university students. It is proposed that enjoyment of the course and the deep approach could be increased by incorporation of more clinical material which is what the students liked most. Anat Sci Educ 10: 560-569. © 2017 American Association of Anatomists. © 2017 American Association of Anatomists.

Fire and vegetation history on Santa Rosa Island, Channel Islands, and long-term environmental change in southern California

USGS Publications Warehouse

Starratt, Scott W.; Pinter, N.; Anderson, Robert S.; Jass, R.B.

2009-01-01

The long-term history of vegetation and fire was investigated at two locations – Soledad Pond (275 m; from ca. 12 000 cal. a BP) and Abalone Rocks Marsh (0 m; from ca. 7000 cal. a BP) – on Santa Rosa Island, situated off the coast of southern California. A coastal conifer forest covered highlands of Santa Rosa during the last glacial, but by ca. 11 800 cal. a BP Pinus stands, coastal sage scrub and grassland replaced the forest as the climate warmed. The early Holocene became increasingly drier, particularly after ca. 9150 cal. a BP, as the pond dried frequently, and coastal sage scrub covered the nearby hillslopes. By ca. 6900 cal. a BP grasslands recovered at both sites. Pollen of wetland plants became prominent at Soledad Pond after ca. 4500 cal. a BP, and at Abalone Rocks Marsh after ca. 3465 cal. a BP. Diatoms suggest freshening of the Abalone Rocks Marsh somewhat later, probably by additional runoff from the highlands. Introduction of non-native species by ranchers occurred subsequent to AD 1850. Charcoal influx is high early in the record, but declines during the early Holocene when minimal biomass suggests extended drought. A general increase occurs after ca. 7000 cal. a BP, and especially after ca. 4500 cal. a BP. The Holocene pattern closely resembles population levels constructed from the archaeological record, and suggests a potential influence by humans on the fire regime of the islands, particularly during the late Holocene.

The environment of the last hunters-gatherers and first agro-pastoralists in the western Mediterranean region, between the Rhone and the Northern Apennines (7th - 6th millennium cal. BCE): Attractiveness of the landscape units and settlement patterns

NASA Astrophysics Data System (ADS)

Battentier, Janet; Binder, Didier; Guillon, Sebastien; Maggi, Roberto; Negrino, Fabio; Sénépart, Ingrid; Tozzi, Carlo; Théry-Parisot, Isabelle; Delhon, Claire

2018-03-01

In the north western Mediterranean, in the area between the Rhone River and the Northern Apennines, the last Mesolithic societies (Castelnovian) and the first Neolithic societies (Impressed Ware or Impressa) coexisted during the first half of the 6th millennium cal. BCE (Before Common Era). Linking the two settlement distribution patterns (mainly high lands and low lands for the Castelnovian versus Mediterranean coastal areas for the Impressa) to their specific environmental backgrounds during that period of coexistence enables us to document the attractiveness of the various available landscape units as a function of the subsistence practices (hunting, fishing and gathering versus agro-pastoralism). Pollen and charcoal data from 41 archaeological sites along with contemporaneous natural (off archaeological sites) sequences (hereafter referred to as "off-site sequences") from three windows (Provence/Western Liguria, the middle Rhone valley/Prealps and Southern Alps, Eastern Liguria/Northern Apennines) were examined in order to reconstruct the vegetal landscape in the surroundings of the Mesolithic and Neolithic settlements between 6500 and 5400 cal. BCE. The importance of environmental versus cultural factors in the settlement preferences of both groups is discussed in order to document our reflection concerning non-consensual issues, such as the existence of interaction or avoidance behaviours or the sharing (or not) of parts or all of the territory and of its natural resources. The results notably highlight the expansion of fir forests that, based on ecological and accessibility criteria, could be considered as rather inauspicious for settlement and hunting as well as for pastoral activities. This expansion may have influenced the settlement patterns of both cultural complexes, leading populations to locate their settlements principally within landscape units that remained clear of extensive fir forests. It appears that, despite being motivated by the prevailing

Undocumented in Honors

ERIC Educational Resources Information Center

Aramburo, Kimberly; Bhavsar, Suketu

2013-01-01

During her time at the Kellogg Honors College at Cal Poly Pomona, Suketu Bhavsar has encountered several high-achieving students who, after coming to trust her, have revealed themselves to her as undocumented. These students came to the United States as children through non-legal channels, generally brought by their families, who were searching…

Medical Surveillance Monthly Report. Volume 19, Number 5

DTIC Science & Technology

2012-05-01

genital herpes ” (ICD-9-CM 054.1 with any fi ft h digit) in any diagnostic position. Incidence rates of MHD were com- pared between three groups of active...cervi- cal cancers and 80 percent of genital warts, was licensed in the United States.2 Consis- tent with the Centers for Disease Control and

Faculty Perceptions Regarding the Infusion of Global Perspectives into the College of Agriculture and Life Sciences Curriculum: A Comparative Study

ERIC Educational Resources Information Center

Magtoto, Ronaldo Lising

2017-01-01

A comparative study was conducted to explore faculty perceptions regarding the infusion of global perspectives into the College of Agriculture and Life Sciences (CALS) curriculum at Iowa State University. King (1991) provided the original base for the study which enabled a comparison with data recently collected. This study may fill a void in the…

Recent Studies of Chemical Interactions on Surfaces Using Molecular Beams

DTIC Science & Technology

1976-01-26

going to the mobile chemisorbed state. Procop and Volter report an entropy increase of about 20 cal/mole OK for hydrogen chemisorption on platinum, for...31. I) 35. A. George Stoll, Jr., Ph.D. Thsis, Depam t of Chmial Nagineering, U.C.B. 36. it. P. eiurr-., private commication. 0 37. N. Procop and J