Science.gov

Sample records for californium 250 target

  1. Californium

    NASA Astrophysics Data System (ADS)

    Haire, Richard G.

    The discovery of californium came in the era of the syntheses and identifications of other transplutonium elements, following the end of World War II. The discovery of the element californium, like many of the other actinide elements, hinged on the development of new experimental techniques in conjunction with predictions based on nuclear systematics. Californium was named after the University and State of California where many of the transuranium elements were first identified. This element was discovered by Thompson, Street, Ghiorso, and Seaborg (Hyde et al., 1971; Seaborg and Loveland, 1990) in February, 1950. The discovery of californium came only 2 months after the preparation and identification of the first isotope of berkelium, element 97 (see Chapter 10). An account of the discovery and reminiscences about the early work on californium has been given by Ghiorso (1983).

  2. Ion-exchange chromatographic separation of einsteinium from irradiated californium targets

    SciTech Connect

    Elesin, A.A.; Nikolaev, V.M.; Shalimov, V.V.; Popov, Yu.S.; Kovantsev, V.N.; Tselishchev, I.V.; Filimonov, V.T.; Mishenev, V.B.; Yadovin, A.A.; Golosovskii, L.S.; Chetverikov, A.P.

    1987-07-01

    Einsteinium was obtained by preparing two experimental californium targets and subjecting them to neutron irradiation in a high-flux reactor. The einsteinium was separated from the bombarded targets on a column packed with KU-2U sulfonated cation-exchange resin (20-50 ..mu..m) and eluted at room temperature with an ammonium ..cap alpha..-hydroxyisobutyrate solution. Three successive separation cycles removed californium to produce einsteinium in 68% yield with a decontamination factor of 5.3 x 10/sup 6/. About 20% of the einsteinium was used up by analysis and 11% remained in intermediate fractions. The method developed yielded pure einsteinium with little fission products present. The contribution of the fission products to the total einsteinium gamma-irradiation dose rate was no greater than 81%, due primarily to the radioisotope terbium-160.

  3. Electrodeposition of Californium Using Isobutanol and Aqueous Ammonium Acetate

    NASA Astrophysics Data System (ADS)

    Matoš, Milan; Boll, Rose A.; Phelps, Clarice E.; Torrico, Matthew N.; van Cleve, Shelley M.; Lewis, Benjamin E.

    2013-10-01

    Californium sources and targets are used in many applications in research and industry. Molecular deposition (commonly referred to as electrodeposition) is an experimental technique suitable for production of californium thin films. We are investigating molecular depositions using isobutanol and aqueous ammonium acetate solvents at various conditions to optimize for the best deposition efficiency and repeatability. Results of those tests will be presented.

  4. Preparation of metallic californium

    SciTech Connect

    Radchenko, V.M.; Seleznev, A.G.; Droznik, R.R.; Iebedeva, L.S.; Ryabinin, M.A.; Shushakov, V.D.; Vasil'ev, V.Ya.; Ermishev, V.T.

    1987-03-01

    A sample of metallic californium-249 with a mass of 710 ..mu..g was obtained in the form of a layer with a thickness of 2.4 +/- 0.3 ..mu..m on a quartz support. The overall yield of the vaporized metal was 84% of the starting amount of californium, and the yield of the metal on the support was 46%. It was established that metallic californium has a double hexagonal close-packed (hcp) structure of the ..cap alpha..-La type with the following parameters: a = 0.3380 +/- 0.0002, c = 1.1025 +/- 0.0002, c/2a = 1.631 +/- 0.001 nm, metallic radius 0.1689 +/- 0.0002 nm, and x-ray density 15.18 +/- 0.02 g/cm/sup 3/.

  5. Californium--palladium metal neutron source material

    DOEpatents

    Dahlen, B.L.; Mosly, W.C. Jr.; Smith, P.K.; Albenesius, E.L.

    1974-01-22

    Californium, as metal or oxide, is uniformly dispersed throughout a noble metal matrix, provided in compact, rod or wire form. A solution of californium values is added to palladium metal powder, dried, blended and pressed into a compact having a uni-form distribution of californium. The californium values are decomposed to californium oxide or metal by heating in an inert or reducing atmosphere. Sintering the compact to a high density closes the matrix around the dispersed californium. The sintered compact is then mechanically shaped into an elongated rod or wire form. (4 claims, no drawings) (Official Gazette)

  6. Californium Electrodepositions at Oak Ridge National Laboratory

    SciTech Connect

    Boll, Rose Ann

    2015-01-01

    Electrodepositions of californium isotopes were successfully performed at Oak Ridge National Laboratory (ORNL) during the past year involving two different types of deposition solutions, ammonium acetate (NH4C2H3O2) and isobutanol ((CH3)2CHCH2OH). A californium product that was decay enriched in 251Cf was recovered for use in super-heavy element (SHE) research. This neutron-rich isotope, 251Cf, provides target material for SHE research for the potential discovery of heavier isotopes of Z=118. The californium material was recovered from aged 252Cf neutron sources in storage at ORNL. These sources have decayed for over 30 years, thus providing material with a very high 251Cf-to-252Cf ratio. After the source capsules were opened, the californium was purified and then electrodeposited using the isobutanol method onto thin titanium foils for use in an accelerator at the Joint Institute for Nuclear Research in Dubna, Russia. Another deposition method, ammonium acetate, was used to produce a deposition containing 1.7 0.1 Ci of 252Cf onto a stainless steel substrate. This was the largest single electrodeposition of 252Cf ever prepared. The 252Cf material was initially purified using traditional ion exchange media, such as AG50-AHIB and AG50-HCl, and further purified using a TEVA-NH4SCN system to remove any lanthanides, resulting in the recovery of 3.6 0.1 mg of purified 252Cf. The ammonium acetate deposition was run with a current of 1.0 amp, resulting in a 91.5% deposition yield. Purification and handling of the highly radioactive californium material created additional challenges in the production of these sources.

  7. Californium source transfer

    SciTech Connect

    Wallace, C.R.

    1995-12-31

    In early 1995, the receipt of four sealed californium-252 sources from Oak Ridge National Lab was successfully accomplished by a team comprised of Radiological Engineering, Radiological Operations and Health Physics Instrumentation personnel. A procedure was developed and walked-down by the participants during a Dry Run Evolution. Several special tools were developed during the pre-planning phases of the project which reduced individual and job dose to minimal levels. These included a mobile lifting device for attachment of a transfer ball valve assembly to the undercarriage of the Cannonball Carrier, a transfer tube elbow to ensure proper angle of the source transfer tube, and several tools used during emergency response for remote retrieval and handling of an unshielded source. Lessons were learned in the areas of contamination control, emergency preparedness, and benefits of thorough pre-planning, effectiveness of locally creating and designing special tools to reduce worker dose, and methods of successfully accomplishing source receipt evolutions during extreme or inclement weather.

  8. Californium purification and electrodeposition

    DOE PAGES

    Burns, Jonathan D.; Van Cleve, Shelley M.; Smith, Edward Hamilton; ...

    2014-11-30

    The staff at the Radiochemical Engineering Development Center, located at Oak Ridge National Laboratory, produced a 6.3 ± 0.4 GBq (1.7 ± 0.1 Ci) 252Cf source for the Californium Rare Isotope Breeder Upgrade (CARIBU) project at Argonne National Laboratory’s Argonne Tandem Linac Accelerator System. The source was produced by electrodeposition of a 252Cf sample onto a stainless steel substrate, which required material free from excess mass for efficient deposition. The resulting deposition was the largest reported 252Cf electrodeposition source ever produced. Several different chromatographic purification methods were investigated to determine which would be most effective for final purification of themore » feed material used for the CARIBU source. The separation of lanthanides from the Cf was of special concern. Furthermore, the separation, using 145Sm, 153Gd, and 249Cf as tracers, was investigated using BioRad AG 50X8 in α-hydroxyisobutyric acid, Eichrom LN resin in both HNO3 and HCl, and Eichrom TEVA resin in NH4SCN. The TEVA NH4SCN system was found to completely separate 145Sm and 153Gd from 249Cf and was adopted into the purification process used in purifying the 252Cf.« less

  9. Californium purification and electrodeposition

    SciTech Connect

    Burns, Jonathan D.; Van Cleve, Shelley M.; Smith, Edward Hamilton; Boll, Rose Ann

    2014-11-30

    The staff at the Radiochemical Engineering Development Center, located at Oak Ridge National Laboratory, produced a 6.3 ± 0.4 GBq (1.7 ± 0.1 Ci) 252Cf source for the Californium Rare Isotope Breeder Upgrade (CARIBU) project at Argonne National Laboratory’s Argonne Tandem Linac Accelerator System. The source was produced by electrodeposition of a 252Cf sample onto a stainless steel substrate, which required material free from excess mass for efficient deposition. The resulting deposition was the largest reported 252Cf electrodeposition source ever produced. Several different chromatographic purification methods were investigated to determine which would be most effective for final purification of the feed material used for the CARIBU source. The separation of lanthanides from the Cf was of special concern. Furthermore, the separation, using 145Sm, 153Gd, and 249Cf as tracers, was investigated using BioRad AG 50X8 in α-hydroxyisobutyric acid, Eichrom LN resin in both HNO3 and HCl, and Eichrom TEVA resin in NH4SCN. The TEVA NH4SCN system was found to completely separate 145Sm and 153Gd from 249Cf and was adopted into the purification process used in purifying the 252Cf.

  10. Well Logging with Californium-252

    SciTech Connect

    Boulogne, A.R.

    2003-01-06

    Californium-252 is an intense neutron emitter that has only recently become available for experimental well logging. The purpose of this research is to investigate the application of well logging to groundwater hydrology; however, most of the techniques and purposes are quite similar to applications in the petroleum industry.

  11. Separation of Californium from other Actinides

    DOEpatents

    Mailen, J C; Ferris, L M

    1973-09-25

    A method is provided for separating californium from a fused fluoride composition containing californium and at least one element selected from the group consisting of plutonium, americium, curium, uranium, thorium, and protactinium which comprises contacting said fluoride composition with a liquid bismuth phase containing sufficient lithium or thorium to effect transfer of said actinides to the bismuth phase and then contacting the liquid bismuth phase with molten LiCl to effect selective transfer of californium to the chloride phase.

  12. Dosimetry of an Implantable 252 Californium Source

    SciTech Connect

    Oliver, G.D. Jr.

    2001-08-29

    The radiation dose from 252 Californium needles designed for use as a source of neutrons for radiotherapy has been measured. The dosimetry information presented in this paper will enable clinical studies of neutron radiotherapy with 252 Californium needles to be planned and begun.

  13. Structural investigation of californium under pressure

    NASA Astrophysics Data System (ADS)

    Heathman, S.; Le Bihan, T.; Yagoubi, S.; Johansson, B.; Ahuja, R.

    2013-06-01

    The high-pressure structural behavior of californium has been studied experimentally and theoretically up to 100 GPa. A valence change from divalent to trivalent forms was observed under modest pressure revealing californium to be the only actinide to exhibit more than one metallic valence at near to ambient conditions as is the case for cerium in the lanthanide series. Three metallic valencies and four different crystallographic phases were observed in californium as a function of pressure. High-pressure techniques, synchrotron radiation, and ab initio electronic structure calculations of total energies were used to investigate the material and to determine the role which californium's 5f electrons play in influencing these transitions. The crystallographic structures observed are similar to those found in the preceding actinide elements, curium and americium, with the initially localized 5f states becoming completely delocalized under the influence of high pressure.

  14. Californium-252 Neutron Sources for Medical Applications

    SciTech Connect

    Boulogne, A.R.

    2001-08-29

    Californium-252 neutron sources are being prepared to investigate the value of this radionuclide in diagnosing and treating diseases. A source resembling a cell-loaded radium needle was developed for neutron therapy. Since therapy needles are normally implanted in the body, very conservative design criteria were established to prevent leakage of radioactive. Methods are being developed to prepare very intense californium sources that could be used eventually for neutron radiography and for diagnosis by neutron activation analysis. This paper discusses these methods.

  15. Radioactive beams from Californium fission at the CARIBU facility

    NASA Astrophysics Data System (ADS)

    Savard, Guy; Pardo, Richard; Baker, Sam; Davids, Cary; Peterson, Don; Phillips, Don; Vondrasek, Rick; Zabransky, Bruce; Zinkann, Gary

    2009-10-01

    The Californium Rare Ion Breeder Upgrade (CARIBU) of the ATLAS superconducting linac facility aims at providing low energy and reaccelerated neutron-rich radioactive beams to address key nuclear physics and astrophysics questions. These beams are obtained from fission fragments of a 1 Ci ^252Cf source, thermalized and collected into a low-energy particle beam by a helium gas catcher, mass analyzed by an isobar separator, and charge breed to higher charge states for acceleration in ATLAS. The method described is fast and universal and short-lived isotope yield scale essentially with Californium fission yields. Expected intensities of reaccelerated beams are up to ˜5x10^5 (10^7 at low energy) far-from-stability ions per second on target. Initial commissioning is being performed with weaker 2.5 and 80 mCi sources. Commissioning results, together with the nuclear physics and astrophysics program that will be pursued with the neutron-rich beams made available, will be presented. Plans for installation of the 1 Ci source will be discussed.

  16. Radiography with the Fission Neutrons from Californium-252

    DTIC Science & Technology

    1977-07-01

    iftD-Ao45 3^ m-77-B1i2i TECHNICAL 7󈧖 LIBRARY lADfto^^^ RADIOGRAPHY WITH THE FISSION NEUTRONS FROM CALIFORNIUM -252 JOHN J. ANTAL and...TITLE C«id Sub(l(/«J RADIOGRAPHY WITH THE FISSION NEUTRONS FROM CALIFORNIUM -252 5. TYPE OF REPORT it PERIOD COVERED Final Report 6...Cellulose nitrate Californium -252 20. ABSTRACT (Continue on reverse aide 11 necessary and identity by block number) (SEE REVERSE SIDE) DD 1

  17. Neutron production for 250 MeV protons bombarding on thick grain-made tungsten target

    NASA Astrophysics Data System (ADS)

    Zhang, Xueying; Zhang, Yanbin; Ma, Fei; Ju, Yongqin; Chen, Liang; Zhang, Hongbin; Li, Yanyan; Wan, Bo; Wang, Jianguo; Ge, Honglin

    2015-08-01

    Neutron yield for 250 MeV protons incident on a tungsten target has been measured using the water bath method. The target was made of many randomly placed tungsten grains. Through analyzing the activity of Au foils, the neutron flux distribution in water was obtained. The neutrons slowing down process shows that the neutrons from tungsten have an average energy lower than neutrons from the lead target. The neutron yield was experimentally determined to be 2.02 ± 0.15 neutron/proton. Detailed simulation was also performed with the Geant4 toolkit. Comparison has been made with the experimentally derived neutron yield. It was found that, around 250 MeV, experimental results were described satisfactorily with a combination of high-energy spallation, low-energy neutron reaction and scattering. It was shown that the grain-packed target does not affect much the main neutronic properties, which are of crucial importance for the design of the spallation target.

  18. Graphs for Isotopes of 98-Cf (Californium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides a graphic representation of nucleon separation energies and residual interaction parameters for isotopes of the chemical element 98-Cf (Californium, atomic number Z = 98).

  19. Historical Review of Californium-252 Discovery and Development

    DOE R&D Accomplishments Database

    Stoddard, D. H.

    1985-01-01

    This paper discusses the discovery and history of californium 252. This isotope may be synthesized by irradiating plutonium 239, plutonium 242, americium 243, or curium 244 with neutrons in a nuclear reactor. Various experiments and inventions involving Cf conducted at the Savannah River Plant are discussed. The evolution of radiotherapy using californium 252 is reviewed. (PLG)

  20. Investigation of the solvent extraction of californium, fermium and mendelevium.

    PubMed

    Gavrilov, K A; Gvuzdz, E; Starý, J; Seng, W T

    1966-03-01

    The extraction constants for the systems di-(2-ethylhexyl)-orthophosphoric acid/toluene/hydrochloric acid and americium, curium californium and fermium have been determined. They have been used to select the best conditions for the separation of californium, fermium and mendelevium by extraction chromatography. The separation factors are much higher than the corresponding ion-exchange methods.

  1. Historical review of californium-252 discovery and development

    SciTech Connect

    Stoddard, D.H.

    1985-01-01

    This paper discusses the discovery and history of californium 252. This isotope may be synthesized by irradiating plutonium 239, plutonium 242, americium 243, or curium 244 with neutrons in a nuclear reactor. Various experiments and inventions involving /sup 252/Cf conducted at the Savannah River Plant are discussed. The evolution of radiotherapy using californium 252 is reviewed. (PLG)

  2. Historical review of californium-252 discovery and development

    NASA Astrophysics Data System (ADS)

    Stoddard, D. H.

    This paper discusses the discovery and history of californium 252. This isotope may be synthesized by irradiating plutonium 239, plutonium 242, americium 243, or curium 244 with neutrons in a nuclear reactor. Various experiments and inventions involving (252)Cf conducted at the Savannah River Plant are discussed. The evolution of radiotherapy using californium 252 is reviewed.

  3. Californium-252: a remarkable versatile radioisotope

    SciTech Connect

    Osborne-Lee, I.W.; Alexander, C.W.

    1995-10-10

    A product of the nuclear age, Californium-252 ({sup 252}Cf) has found many applications in medicine, scientific research, industry, and nuclear science education. Californium-252 is unique as a neutron source in that it provides a highly concentrated flux and extremely reliable neutron spectrum from a very small assembly. During the past 40 years, {sup 252}Cf has been applied with great success to cancer therapy, neutron radiography of objects ranging from flowers to entire aircraft, startup sources for nuclear reactors, fission activation for quality analysis of all commercial nuclear fuel, and many other beneficial uses, some of which are now ready for further growth. Californium-252 is produced in the High Flux Isotope Reactor (HFIR) and processed in the Radiochemical Engineering Development Center (REDC), both of which are located at the Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee. The REDC/HFIR facility is virtually the sole supplier of {sup 252}Cf in the western world and is the major supplier worldwide. Extensive exploitation of this product was made possible through the {sup 252}Cf Market Evaluation Program, sponsored by the United States Department of Energy (DOE) [then the Atomic Energy Commission (AEC) and later the Energy Research and Development Administration (ERDA)]. This program included training series, demonstration centers, seminars, and a liberal loan policy for fabricated sources. The Market Evaluation Program was instituted, in part, to determine if large-quantity production capability was required at the Savannah River Laboratory (SRL). Because of the nature of the product and the means by which it is produced, {sup 252}Cf can be produced only in government-owned facilities. It is evident at this time that the Oak Ridge research facility can meet present and projected near-term requirements. The production, shipment, and sales history of {sup 252}Cf from ORNL is summarized herein.

  4. Radiation Protection for Safe Handling of Californium 252 Sources

    SciTech Connect

    Wright, C.N.

    2001-08-29

    Californium-252 may be used extensively as a new source of neutrons in the next few years. Because of the high emission rate from spontaneous fission, californium can be fabricated into useful sources that are physically small - one of its major attractions. The first sources were fabricated in the configuration of radium therapy needles. Because the users of these sources may be radiologists and medical personnel unfamiliar with neutron hazards, some of the characteristics of Californium 252 sources are reviewed from a health physics viewpoint in this paper.

  5. Spallation yield of neutrons produced in thick lead target bombarded with 250 MeV protons

    NASA Astrophysics Data System (ADS)

    Chen, L.; Ma, F.; Zhanga, X. Y.; Ju, Y. Q.; Zhang, H. B.; Ge, H. L.; Wang, J. G.; Zhou, B.; Li, Y. Y.; Xu, X. W.; Luo, P.; Yang, L.; Zhang, Y. B.; Li, J. Y.; Xu, J. K.; Liang, T. J.; Wang, S. L.; Yang, Y. W.; Gu, L.

    2015-01-01

    The neutron yield from thick target of Pb irradiated with 250 MeV protons has been studied experimentally. The neutron production was measured with the water-bath gold method. The thermal neutron distributions in the water were determined according to the measured activities of Au foils. Corresponding results calculated with the Monte Carlo code MCNPX were compared with the experimental data. It was found out that the Au foils with cadmium cover significantly changed the spacial distribution of the thermal neutron field. The corrected neutron yield was deduced to be 2.23 ± 0.19 n/proton by considering the influence of the Cd cover on the thermal neutron flux.

  6. Method for fabricating thin californium-containing radioactive source wires

    DOEpatents

    Gross, Ian G; Pierce, Larry A

    2006-08-22

    A method for reducing the cross-sectional diameter of a radioactive californium-containing cermet wire while simultaneously improving the wire diameter to a more nearly circular cross section. A collet fixture is used to reduce the wire diameter by controlled pressurization pulses while simultaneously improving the wire cross-sectional diameter. The method is especially suitable for use in hot cells for the production of optimized cermet brachytherapy sources that contain large amounts of radioactive californium-252.

  7. Development of Californium-252 Miniature Source Assemblies

    SciTech Connect

    Notspecified, N. A.

    2007-06-26

    The purpose of this CRADA between ORNL and lsotron, Inc. is to develop miniature californium-252 sources configured for remote handling that can be used in neutron brachytherapy for treatment of cancer. Brachytherapy places the · radioactive source at or near the site of the tumor, using a catheter. The CRADA ran from late 1999 through November 2005. The heart of a Cf-252 source is the radioactive core wire, which is sealed inside a metallic source capsule. Previous Cf-252 medical sources were based on a cermet wire with californium oxide dispersed in palladium, typically >1-mm diameter and <0.1% Cf-252 by weight. Previously, the standard medical source in the U.S. was the Applicator Tube (AT) source. 23-mm long, 2.8-mm diameter, with ~30 {micro}g of Cf-252, and which required manual loading into patients by medical staff. The goal of this work was to develop capabilities and technology to fabricate higher-intensity Cf-252 sources attached to a positioning cable, with overall diameter approaching that of exist ing photon (iridium-192) brachytherapy sources (i.e., ~1.1 mm). This work was successful in developing and demonstrating new technologies and procedures for the fabrication of miniaturized Cf-252 sources. CRADA-designed equipment reduced the wire diameters significantly (patent pending). Short wire segments were cut and successfully welded inside capsules meeting the miniaturization goals. A batch of seven prototype sources was prepared that met fabrication specifications. Although their neutron emissions were not maximized, they were still several times more intense than the previous AT sources. Very robust source-to-cable attachment methods were demonstrated (patent issued). A shipping canister was designed and built to contain the completed source assembly. lsotron designed and built a computer-controlled remote afterloader system to deliver the new sources for treatments.

  8. Spontaneous Partitioning of Californium from Curium: Curious Cases from the Crystallization of Curium Coordination Complexes

    SciTech Connect

    Cary, Samantha K.; Silver, Mark A.; Liu, Guokui; Wang, Jamie C.; Bogart, Justin A.; Stritzinger, Jared T.; Arico, Alexandra A.; Hanson, Kenneth; Schelter, Eric J.; Albrecht-Schmitt, Thomas E.

    2015-12-07

    The reaction of 248CmCl3 with excess 2,6-pyridinedicarboxylic acid (DPA) under mild solvothermal conditions results in crystallization of the tris-chelate complex Cm(HDPA)3·H2O. Approximately half of the curium remains in solution at the end of this process, and evaporation of the mother liquor results in crystallization of the bis-chelate complex [Cm(HDPA)- (H2DPA)(H2O)2Cl]Cl·2H2O. 248Cm is the daughter of the α decay of 252Cf and is extracted in high purity from this parent. However, trace amounts of 249,250,251Cf are still present in all samples of 248Cm. During the crystallization of Cm(HDPA)3·H2O and [Cm(HDPA)(H2DPA)(H2O)2Cl]Cl·2H2O, californium(III) spontaneously separates itself from the curium complexes and is found doped within crystals of DPA in the form of Cf(HDPA)3. These results add to the growing body of evidence that the chemistry of californium is fundamentally different from that of earlier actinides.

  9. Spontaneous Partitioning of Californium from Curium: Curious Cases from the Crystallization of Curium Coordination Complexes.

    PubMed

    Cary, Samantha K; Silver, Mark A; Liu, Guokui; Wang, Jamie C; Bogart, Justin A; Stritzinger, Jared T; Arico, Alexandra A; Hanson, Kenneth; Schelter, Eric J; Albrecht-Schmitt, Thomas E

    2015-12-07

    The reaction of (248)CmCl3 with excess 2,6-pyridinedicarboxylic acid (DPA) under mild solvothermal conditions results in crystallization of the tris-chelate complex Cm(HDPA)3 · H2O. Approximately half of the curium remains in solution at the end of this process, and evaporation of the mother liquor results in crystallization of the bis-chelate complex [Cm(HDPA)(H2DPA)(H2O)2Cl]Cl·2H2O. (248)Cm is the daughter of the α decay of (252)Cf and is extracted in high purity from this parent. However, trace amounts of (249,250,251)Cf are still present in all samples of (248)Cm. During the crystallization of Cm(HDPA)3 · H2O and [Cm(HDPA)(H2DPA)(H2O)2Cl]Cl · 2H2O, californium(III) spontaneously separates itself from the curium complexes and is found doped within crystals of DPA in the form of Cf(HDPA)3. These results add to the growing body of evidence that the chemistry of californium is fundamentally different from that of earlier actinides.

  10. Calibration of a Modified Californium Shuffler

    SciTech Connect

    Sadowski, E.T.; Armstrong, F.; Oldham, R.; Ceo, R.; Williams, N.

    1995-06-01

    A californium shuffler originally designed to assay hollow cylindrical pieces of UA1 has been modified to assay solid cylinders. Calibration standards were characterized via chemical analysis of the molten UA1 taken during casting of the standards. The melt samples yielded much more reliable characterization data than drill samples taken from standards after the standards had solidified. By normalizing one well-characterized calibration curve to several standards at different enrichments, a relatively small number of standards was required to develop an enrichment-dependent calibration. The precision of this shuffler is 0.65%, and the typical random and systematic uncertainties are 0.53% and 0.73%, respectively, for a six minute assay of an ingot containing approximately 700 grams of {sup 235}U. This paper will discuss (1) the discrepancies encountered when UA1 standards were characterized via melt samples versus drill samples, (2) a calibration methodology employing a small number of standards, and (3) a comparison of results from a previously unused shuffler with an existing shuffler. A small number of UA1 standards have been characterized using samples from the homogeneous molten state and have yielded enrichment-dependent and enrichment-independent calibration curves on two different shufflers.

  11. Californium-252 encapsulation at the Savannah River Laboratory

    SciTech Connect

    Boulogne, A.R.

    1980-01-01

    More than 1 g of the neutron-emitting isotope californium-252 has been encapsulated at SRL for worldwide medical, industrial, and research uses. Bulk sales packages have been prepared for the USDOE sales program since 1971. Doubly-encapsulated sources have been prepared for USDOE's market evaluation program since 1968. Californium-252 sources for loan and sales packages satisfy the criteria for Special Form Radioactive Material. Encapsulation is performed in special neutron-shielded containment facilities at SRL. Development of improved source and shipping package designs and processes is continuing. 17 figures.

  12. Biologically effective doses from californium-252 intracavitary applications.

    PubMed

    Iyer, P S

    1975-02-01

    Californium-252 which emits fission neutrons and gamma rays is being investigated for applications in brachytherapy. From available experimental results, a value of 6.2 had been arrived at as the RBE for cell killing of californium neutrons relative to radium gavva rays for intracavitary applications based on the revised Manchester system of loading. The LET distributions as well as the ratio of neutron to gamma dose-rates have been estimated and are found to remain almost constant in the volume of interest around such applications.

  13. Californium Multiplier Part I: design for neutron radiography

    SciTech Connect

    Crosbie, K.L.; Preskitt, C.A.; John, J.; Hastings, J.D.

    1982-01-01

    The Californium Multiplier (CFX) is a subcritical assembly of enriched uranium surrounding a californium-252 neutron source. The function of the CFX is to multiply the neutrons emitted by the source to a number sufficient for neutron radiography. The CFX is designed to provide a collimated beam of thermal neutrons from which the gamma radiation is filtered, and the scattered neutrons are reduced to make it suitable for high resolution radiography. The entire system has inherent safety features, which provide for system and personnel safety, and it operates at moderate cost. In Part I, the CFX and the theory of its operation are described in detail.

  14. Californium-252: A New Isotopic Source for Neutron Radiography

    SciTech Connect

    Reinig, W.C.

    2001-08-29

    This report discusses a new isotopic source for neutron radiography, Californium-252. Nuclear reactors are the usual source of neutrons for radiography, primarily because of their intense neutron beams. If neutron radiography is to have widespread use, intense transportable neutron sources are required that can be used in plants, in laboratories and in the field.

  15. A Californium-252 Neutron Source for Student Use

    ERIC Educational Resources Information Center

    Bowen, H. J.

    1975-01-01

    Describes an undergraduate chemistry experiment which utilizes small samples of Californium 252 as a neutron source for the activation of 12 other elements. The students prepare decay curves of the radioactive isotopes and perform nondestructive activation analyses for gram amounts of some elements. (MLH)

  16. A Californium-252 Neutron Source for Student Use

    ERIC Educational Resources Information Center

    Bowen, H. J.

    1975-01-01

    Describes an undergraduate chemistry experiment which utilizes small samples of Californium 252 as a neutron source for the activation of 12 other elements. The students prepare decay curves of the radioactive isotopes and perform nondestructive activation analyses for gram amounts of some elements. (MLH)

  17. A summary of SEU test results using californium-252

    SciTech Connect

    Sorensen, R.H.; Adams, L.; Sanderson, T.K.

    1988-12-01

    This paper presents a summary of four years Single Event Upset (SEU) test results on a wide range of devices and technologies using Californium-252 having an average Linear Energy Transfer (LET) = 43 MeV/(mg/sqcm). Sensitivity variations are highlighted, particularly for nominally identical devices. The significance of the testing and test data with respect to recent devices and technologies is discussed.

  18. Shielding variation effects for 250 MeV protons on tissue targets.

    PubMed

    Brandl, A; Hranitzky, C; Rollet, S

    2005-01-01

    This paper provides results of computer simulation studies with the goal to analyse issues regarding radiation protection for personnel, patients and third persons involved in hadron therapy treatment. The treatment room and the patient are modelled by simple cylindrical geometries at incident proton energies of 250 MeV. Monte Carlo simulations of the energy and angular dependence of proton, neutron and photon radiation fields and resulting ambient dose equivalent distributions outside the shielding walls are performed. In order to investigate systematic uncertainties due to the shielding materials and inherent to the computer models, various concrete compositions, densities and water contents are modelled, and the influence of simulation parameters on the results obtained is determined. Generally, good agreement is found between results provided by MCNPX and FLUKA computer codes. Variations in neutron ambient dose attenuation from -50 to +/-30% are found due to varying concrete composition. Changes in the water content of the concrete in the order of 8% may cause variations up to 20%.

  19. Californium Multiplier. Part I. Design for neutron radiography

    SciTech Connect

    Crosbie, K.L.; Preskitt, C.A.; John, J.; Hastings, J.D.

    1982-04-01

    The Californium Multiplier (CFX) is a subcritical assembly of enriched uranium surrounding a californium-252 neutron source. The function of the CFX is to multiply the neutrons emitted by the source to a number sufficient for neutron radiography. The CFX is designed to provide a collimated beam of thermal neutrons from which the gamma radiation is filtered, and the scattered neutrons are reduced to make it suitable for high resolution radiography. The entire system has inherent safety features, which provide for system and personnel safety, and it operates at moderate cost. In Part I, the CFX and the theory of its operation are described in detail. Part II covers the performance of the Mound Facility CFX.

  20. Production, distribution and applications of californium-252 neutron sources.

    PubMed

    Martin, R C; Knauer, J B; Balo, P A

    2000-01-01

    The radioisotope 252Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6-yr half-life. A source the size of a person's little finger can emit up to 10(11) neutrons s(-1). Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement and minerals, as well as for detection and identification of explosives, land mines and unexploded military ordinance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 yr of experience and by US Bureau of Mines tests of source survivability during explosions. The production and distribution center for the US Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory (ORNL). DOE sells 252Cf to commercial reencapsulators domestically and internationally. Sealed 252Cf sources are also available for loan to agencies and subcontractors of the US government and to universities for educational, research and medical applications. The REDC has established the Californium User Facility (CUF) for Neutron Science to make its large inventory of 252Cf sources available to researchers for irradiations inside uncontaminated hot cells. Experiments at the CUF include a land mine detection system, neutron damage testing of solid-state detectors, irradiation of human cancer cells for boron neutron capture therapy experiments and irradiation of rice to induce genetic mutations.

  1. Production, Distribution, and Applications of Californium-252 Neutron Sources

    SciTech Connect

    Balo, P.A.; Knauer, J.B.; Martin, R.C.

    1999-10-03

    The radioisotope {sup 252}Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6-year half-life. A source the size of a person's little finger can emit up to 10{sup 11} neutrons/s. Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement, and minerals, as well as for detection and identification of explosives, laud mines, and unexploded military ordnance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards, and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 years of experience and by U.S. Bureau of Mines tests of source survivability during explosions. The production and distribution center for the U. S Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory (ORNL). DOE sells The radioisotope {sup 252}Cf is routinely encapsulated into compact, portable, intense neutron sources with a 2.6- year half-life. A source the size of a person's little finger can emit up to 10 neutrons/s. Californium-252 is used commercially as a reliable, cost-effective neutron source for prompt gamma neutron activation analysis (PGNAA) of coal, cement, and minerals, as well as for detection and identification of explosives, laud mines, and unexploded military ordnance. Other uses are neutron radiography, nuclear waste assays, reactor start-up sources, calibration standards, and cancer therapy. The inherent safety of source encapsulations is demonstrated by 30 years of experience and by U.S. Bureau of Mines tests of source survivability during explosions. The production and distribution center for the U. S Department of Energy (DOE) Californium Program is the Radiochemical Engineering Development Center (REDC) at Oak Ridge National Laboratory(ORNL). DOE sells {sup 252}Cf to commercial

  2. Atomic Mass and Nuclear Binding Energy for Cf-327 (Californium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Cf-327 (Californium, atomic number Z = 98, mass number A = 327).

  3. Atomic Mass and Nuclear Binding Energy for Cf-326 (Californium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Cf-326 (Californium, atomic number Z = 98, mass number A = 326).

  4. Atomic Mass and Nuclear Binding Energy for Cf-330 (Californium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Cf-330 (Californium, atomic number Z = 98, mass number A = 330).

  5. Atomic Mass and Nuclear Binding Energy for Cf-329 (Californium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Cf-329 (Californium, atomic number Z = 98, mass number A = 329).

  6. Atomic Mass and Nuclear Binding Energy for Cf-328 (Californium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Cf-328 (Californium, atomic number Z = 98, mass number A = 328).

  7. Study of neutron spectra in a water bath from a Pb target irradiated by 250 MeV protons

    NASA Astrophysics Data System (ADS)

    Li, Yan-Yan; Zhang, Xue-Ying; Ju, Yong-Qin; Ma, Fei; Zhang, Hong-Bin; Chen, Liang; Ge, Hong-Lin; Wan, Bo; Luo, Peng; Zhou, Bin; Zhang, Yan-Bin; Li, Jian-Yang; Xu, Jun-Kui; Wang, Song-Lin; Yang, Yong-Wei; Yang, Lei

    2015-04-01

    Spallation neutrons were produced by the irradiation of Pb with 250 MeV protons. The Pb target was surrounded by water which was used to slow down the emitted neutrons. The moderated neutrons in the water bath were measured by using the resonance detectors of Au, Mn and In with a cadmium (Cd) cover. According to the measured activities of the foils, the neutron flux at different resonance energies were deduced and the epithermal neutron spectra were proposed. Corresponding results calculated with the Monte Carlo code MCNPX were compared with the experimental data to check the validity of the code. The comparison showed that the simulation could give a good prediction for the neutron spectra above 50 eV, while the finite thickness of the foils greatly effected the experimental data in low energy. It was also found that the resonance detectors themselves had great impact on the simulated energy spectra. Supported by National Natural Science Foundation and Strategic Priority Research Program of the Chinese Academy of Sciences (11305229, 11105186, 91226107, 91026009, XDA03030300)

  8. Preliminary observations on californium-252 behaviour in sea water, sediments and zooplankton.

    PubMed

    Aston, S R; Fowler, S W

    1983-04-01

    We carried out radiotracer experiments on the behaviour of 252Cf in the marine environment. The particulate fraction of californium in sea water approached 45% after four days. Californium rapidly adsorbed onto marine coastal and deep-sea sediments with Kd values from 1.4 X 10(4) to greater than or equal to 1 X 10(5). The concentration of 252Cf in euphausiids reached near-equilibrium factors of 3 X 10(2) in water after one week; in contrast, the assimilation from food was very low. Excreted fecal pellets, molts and zooplankton carcasses are potentially important vectors for californium re-distribution in the oceans.

  9. Potentially-lethal damage and radioprotection in human cells exposed to californium-252

    SciTech Connect

    Schroy, C.B.; Goud, S.N.; Magura, C.; Feola, J.M.; Maruyama, Y.

    1986-01-01

    Cultured human T-1E cells were irradiated with californium-252 neutrons and gamma rays. When 2 mm caffeine was present in the medium for 47 h after irradiation cell survival (assayed by colony formation) was decreased significantly. When 2 m dimethylsulfoxide was present during the irradiations radioprotection was observed using the same assay. The caffeine data indicate that potentially-lethal lesions exist in cells after californium exposure and that these lesions can be made lethal when they would otherwise be repaired. The DMSO data indicate that radioprotection from californium exposure can be achieved and that scanvengable free radicals play an important role in Cf-252 lethality.

  10. Design, construction, and characterization of a facility for neutron capture gamma ray analysis of sulfur in coal using californium-252

    SciTech Connect

    Layfield, J.R.

    1980-03-01

    A study of neutron capture gamma ray analysis of sulfur in coal using californium-252 as a neutron source is reported. Both internal and external target geometries are investigated. The facility designed for and used in this study is described. The external target geometry is found to be inappropriate because of the low thermal neutron flux at the sample location, which must be outside the biological shielding. The internal target geometry is found to have a sufficient thermal neutron flux, but an excessive gamma ray background. A water filled plastic facility, rather than the paraffin filled steel one used in this study, is suggested as a means of increasing flexibility and decreasing the beackground in the internal target geometry.

  11. Unusual structure, bonding and properties in a californium borate.

    PubMed

    Polinski, Matthew J; Garner, Edward B; Maurice, Rémi; Planas, Nora; Stritzinger, Jared T; Parker, T Gannon; Cross, Justin N; Green, Thomas D; Alekseev, Evgeny V; Van Cleve, Shelley M; Depmeier, Wulf; Gagliardi, Laura; Shatruk, Michael; Knappenberger, Kenneth L; Liu, Guokui; Skanthakumar, S; Soderholm, Lynda; Dixon, David A; Albrecht-Schmitt, Thomas E

    2014-05-01

    The participation of the valence orbitals of actinides in bonding has been debated for decades. Recent experimental and computational investigations demonstrated the involvement of 6p, 6d and/or 5f orbitals in bonding. However, structural and spectroscopic data, as well as theory, indicate a decrease in covalency across the actinide series, and the evidence points to highly ionic, lanthanide-like bonding for late actinides. Here we show that chemical differentiation between californium and lanthanides can be achieved by using ligands that are both highly polarizable and substantially rearrange on complexation. A ligand that suits both of these desired properties is polyborate. We demonstrate that the 5f, 6d and 7p orbitals are all involved in bonding in a Cf(III) borate, and that large crystal-field effects are present. Synthetic, structural and spectroscopic data are complemented by quantum mechanical calculations to support these observations.

  12. Unusual structure, bonding and properties in a californium borate

    NASA Astrophysics Data System (ADS)

    Polinski, Matthew J.; Garner, Edward B.; Maurice, Rémi; Planas, Nora; Stritzinger, Jared T.; Parker, T. Gannon; Cross, Justin N.; Green, Thomas D.; Alekseev, Evgeny V.; van Cleve, Shelley M.; Depmeier, Wulf; Gagliardi, Laura; Shatruk, Michael; Knappenberger, Kenneth L.; Liu, Guokui; Skanthakumar, S.; Soderholm, Lynda; Dixon, David A.; Albrecht-Schmitt, Thomas E.

    2014-05-01

    The participation of the valence orbitals of actinides in bonding has been debated for decades. Recent experimental and computational investigations demonstrated the involvement of 6p, 6d and/or 5f orbitals in bonding. However, structural and spectroscopic data, as well as theory, indicate a decrease in covalency across the actinide series, and the evidence points to highly ionic, lanthanide-like bonding for late actinides. Here we show that chemical differentiation between californium and lanthanides can be achieved by using ligands that are both highly polarizable and substantially rearrange on complexation. A ligand that suits both of these desired properties is polyborate. We demonstrate that the 5f, 6d and 7p orbitals are all involved in bonding in a Cf(III) borate, and that large crystal-field effects are present. Synthetic, structural and spectroscopic data are complemented by quantum mechanical calculations to support these observations.

  13. In-beam gamma-ray spectroscopy of {sup 248,250,252}Cf by neutron-transfer reactions using a Cf target

    SciTech Connect

    Takahashi, R.; Ishii, T.; Asai, M.; Nagae, D.; Makii, H.; Tsukada, K.; Toyoshima, A.; Ishii, Y.; Matsuda, M.; Makishima, A.; Shizuma, T.; Kohno, T.; Ogawa, M.

    2010-05-15

    The ground-state bands of {sup 248,250,252}Cf have been established up to the 10{sup +}, 12{sup +}, and 10{sup +} states, respectively, by in-beam gamma-ray spectroscopy using neutron-transfer reactions with a 153-MeV {sup 18}O beam and a highly radioactive Cf target. The deexcitation gamma rays in {sup 248,250,252}Cf were identified by taking coincidences with outgoing particles of {sup 16-19}O measured with Si DELTAE-E detectors, and by selecting their kinetic energies. Moments of inertia of {sup 248,250,252}Cf were discussed in terms of the N=152 deformed shell gap.

  14. Metastable charge-transfer state of californium(iii) compounds.

    PubMed

    Liu, Guokui; Cary, Samantha K; Albrecht-Schmitt, Thomas E

    2015-06-28

    Among a series of anomalous physical and chemical properties of Cf(iii) compounds revealed by recent investigations, the present work addresses the characteristics of the optical spectra of An(HDPA)3·H2O (An = Am, Cm, and Cf), especially the broadband photoluminescence from Cf(HDPA)3·H2O induced by ligand-to-metal charge transfer (CT). As a result of strong ion-ligand interactions and the relative ease of reducing Cf(iii) to Cf(ii), a CT transition occurs at low energy (<3 eV) via the formation of a metastable Cf(ii) state. It is shown that the systematic trend in CT transitions of the lanthanide series is not paralleled by actinide elements lighter than Cf(iii), and californium represents a turning point in the periodicity of the actinide series. Analyses and modeling of the temperature-dependent luminescence dynamics indicate that the metastable Cf(ii) charge-transfer state undergoes radiative and non-radiative relaxations. Broadening of the CT transition arises from strong vibronic coupling and hole-charge interactions in the valence band. The non-radiative relaxation of the metastable CT state results from a competition between phonon-relaxation and thermal tunneling that populates the excited states of Cf(iii).

  15. Teratogenic effect of californium-252 irradiation in rats.

    PubMed

    Satow, Y; Lee, J Y; Hori, H; Okuda, H; Tsuchimoto, S; Sawada, S; Yokoro, K

    1989-06-01

    The teratogenicity of californium-252 (Cf-252) irradiation which generates approximately 70% 2.3 MeV fast neutron and 30% gamma rays was evaluated. A single whole body exposure of Cf-252 at various doses was given to pregnant rats on day 8 or 9 of pregnancy, followed by microscopic autopsy of the fetuses at the terminal stage of pregnancy to search for external and internal malformations. For comparison, pregnant rats were irradiated with various doses of cobalt-60 (Co-60) standard gamma rays at the same dose rate (1 rad/min.). The doses were 20-120 rad of Cf-252 and 80-220 rad of Co-60. Using frequency of radiation induced malformations observed on day 8 of pregnancy as an index, relative biological effectiveness (RBE) of 2.3-2.7 was obtained from the straight line obtained by modifying by the least squares method the frequency curves of malformed fetuses in total implants and in surviving fetuses. The types of malformations induced by Cf-252 and Co-60 irradiation were alike. Using fetal LD50 as an index, 2.4 was obtained as RBE when irradiated on day 8 of pregnancy and 3.1 as that when irradiated on day 9. The results showed that Cf-252 had stronger a teratogenic effect than Co-60 gamma rays.

  16. Emergence of californium as the second transitional element in the actinide series

    SciTech Connect

    Cary, Samantha K.; Vasiliu, Monica; Baumbach, Ryan E.; Stritzinger, Jared T.; Green, Thomas D.; Diefenbach, Kariem; Cross, Justin N.; Knappenberger, Kenneth L.; Liu, Guokui; Silver, Mark A.; DePrince, A. Eugene; Polinski, Matthew J.; Van Cleve, Shelley M.; House, Jane H.; Kikugawa, Naoki; Gallagher, Andrew; Arico, Alexandra A.; Dixon, David A.; Albrecht-Schmitt, Thomas E.

    2015-04-16

    A break in periodicity occurs in the actinide series between plutonium and americium as the result of the localization of 5f electrons. The subsequent chemistry of later actinides is thought to closely parallel lanthanides in that bonding is expected to be ionic and complexation should not substantially alter the electronic structure of the metal ions. Here we demonstrate that ligation of californium(III) by a pyridine derivative results in significant deviations in the properties of the resultant complex with respect to that predicted for the free ion. We expand on this by characterizing the americium and curium analogues for comparison, and show that these pronounced effects result from a second transition in periodicity in the actinide series that occurs, in part, because of the stabilization of the divalent oxidation state. As a result, the metastability of californium(II) is responsible for many of the unusual properties of californium including the green photoluminescence.

  17. Emergence of californium as the second transitional element in the actinide series.

    PubMed

    Cary, Samantha K; Vasiliu, Monica; Baumbach, Ryan E; Stritzinger, Jared T; Green, Thomas D; Diefenbach, Kariem; Cross, Justin N; Knappenberger, Kenneth L; Liu, Guokui; Silver, Mark A; DePrince, A Eugene; Polinski, Matthew J; Van Cleve, Shelley M; House, Jane H; Kikugawa, Naoki; Gallagher, Andrew; Arico, Alexandra A; Dixon, David A; Albrecht-Schmitt, Thomas E

    2015-04-16

    A break in periodicity occurs in the actinide series between plutonium and americium as the result of the localization of 5f electrons. The subsequent chemistry of later actinides is thought to closely parallel lanthanides in that bonding is expected to be ionic and complexation should not substantially alter the electronic structure of the metal ions. Here we demonstrate that ligation of californium(III) by a pyridine derivative results in significant deviations in the properties of the resultant complex with respect to that predicted for the free ion. We expand on this by characterizing the americium and curium analogues for comparison, and show that these pronounced effects result from a second transition in periodicity in the actinide series that occurs, in part, because of the stabilization of the divalent oxidation state. The metastability of californium(II) is responsible for many of the unusual properties of californium including the green photoluminescence.

  18. Emergence of californium as the second transitional element in the actinide series

    DOE PAGES

    Cary, Samantha K.; Vasiliu, Monica; Baumbach, Ryan E.; ...

    2015-04-16

    A break in periodicity occurs in the actinide series between plutonium and americium as the result of the localization of 5f electrons. The subsequent chemistry of later actinides is thought to closely parallel lanthanides in that bonding is expected to be ionic and complexation should not substantially alter the electronic structure of the metal ions. Here we demonstrate that ligation of californium(III) by a pyridine derivative results in significant deviations in the properties of the resultant complex with respect to that predicted for the free ion. We expand on this by characterizing the americium and curium analogues for comparison, andmore » show that these pronounced effects result from a second transition in periodicity in the actinide series that occurs, in part, because of the stabilization of the divalent oxidation state. As a result, the metastability of californium(II) is responsible for many of the unusual properties of californium including the green photoluminescence.« less

  19. Biomedical neutron research at the Californium User Facility for neutron science

    SciTech Connect

    Martin, R.C.; Byrne, T.E.; Miller, L.F.

    1997-04-01

    The Californium User Facility for Neutron Science has been established at Oak Ridge National Laboratory (ORNL). The Californium User Facility (CUF) is a part of the larger Californium Facility, which fabricates and stores compact {sup 252}Cf neutron sources for worldwide distribution. The CUF can provide a cost-effective option for research with {sup 252}Cf sources. Three projects at the CUF that demonstrate the versatility of {sup 252}Cf for biological and biomedical neutron-based research are described: future establishment of a {sup 252}Cf-based neutron activation analysis system, ongoing work to produce miniature high-intensity, remotely afterloaded {sup 252}Cf sources for tumor therapy, and a recent experiment that irradiated living human lung cancer cells impregnated with experimental boron compounds to test their effectiveness for boron neutron capture therapy.

  20. Proposed Californium-252 User Facility for Neutron Science at Oak Ridge National Laboratory

    SciTech Connect

    Martin, R.C.; Laxson, R.R.; Knauer, J.B.

    1996-10-01

    The Radiochemical Engineering Development Center (REDC) at ORNL has petitioned to establish a Californium-252 User Facility for Neutron Science for academic, industrial, and governmental researchers. The REDC Californium Facility (CF) stores the national inventory of sealed {sup 252}Cf neutron source for university and research loans. Within the CF, the {sup 252}Cf storage pool and two uncontaminated hot cells currently in service for the Californium Program will form the physical basis for the User Facility. Relevant applications include dosimetry and experiments for neutron tumor therapy; fast and thermal neutron activation analysis of materials; experimental configurations for prompt gamma neutron activation analysis; neutron shielding and material damage studies; and hardness testing of radiation detectors, cameras, and electronics. A formal User Facility simplifies working arrangements and agreements between US DOE facilities, academia, and commercial interests.

  1. Emergence of californium as the second transitional element in the actinide series

    PubMed Central

    Cary, Samantha K.; Vasiliu, Monica; Baumbach, Ryan E.; Stritzinger, Jared T.; Green, Thomas D.; Diefenbach, Kariem; Cross, Justin N.; Knappenberger, Kenneth L.; Liu, Guokui; Silver, Mark A.; DePrince, A. Eugene; Polinski, Matthew J.; Van Cleve, Shelley M.; House, Jane H.; Kikugawa, Naoki; Gallagher, Andrew; Arico, Alexandra A.; Dixon, David A.; Albrecht-Schmitt, Thomas E.

    2015-01-01

    A break in periodicity occurs in the actinide series between plutonium and americium as the result of the localization of 5f electrons. The subsequent chemistry of later actinides is thought to closely parallel lanthanides in that bonding is expected to be ionic and complexation should not substantially alter the electronic structure of the metal ions. Here we demonstrate that ligation of californium(III) by a pyridine derivative results in significant deviations in the properties of the resultant complex with respect to that predicted for the free ion. We expand on this by characterizing the americium and curium analogues for comparison, and show that these pronounced effects result from a second transition in periodicity in the actinide series that occurs, in part, because of the stabilization of the divalent oxidation state. The metastability of californium(II) is responsible for many of the unusual properties of californium including the green photoluminescence. PMID:25880116

  2. Production of new superheavy Z=108-114 nuclei with U238, Pu244, and Cm248,250 targets

    NASA Astrophysics Data System (ADS)

    Feng, Zhao-Qing; Jin, Gen-Ming; Li, Jun-Qing

    2009-11-01

    Within the framework of the dinuclear system (DNS) model, production cross sections of new superheavy nuclei with charged numbers Z=108-114 are analyzed systematically. Possible combinations based on the actinide nuclides U238, Pu244, and Cm248,250 with the optimal excitation energies and evaporation channels are pointed out to synthesize new isotopes that lie between the nuclides produced in the cold fusion reactions and the Ca48-induced fusion reactions experimentally, which are feasible to be constructed experimentally. It is found that the production cross sections of superheavy nuclei decrease drastically with the charged numbers of compound nuclei. Larger mass asymmetries of the entrance channels enhance the cross sections in 2n-5n channels.

  3. Beyond Californium-A Neutron Generator Alternative for Dosimetry and Instrument Calibration in the U.S.

    PubMed

    Piper, Roman K; Mozhayev, Andrey V; Murphy, Mark K; Thompson, Alan K

    2017-09-01

    Evaluations of neutron survey instruments, area monitors, and personal dosimeters rely on reference neutron radiations, which have evolved from the heavy reliance on (α,n) sources to a shared reliance on (α,n) and the spontaneous fission neutrons of californium-252 (Cf). Capable of producing high dose equivalent rates from an almost point source geometry, the characteristics of Cf are generally more favorable when compared to the use of (α,n) and (γ,n) sources or reactor-produced reference neutron radiations. Californium-252 is typically used in two standardized configurations: unmoderated, to yield a fission energy spectrum; or with the capsule placed within a heavy-water moderating sphere to produce a softened spectrum that is generally considered more appropriate for evaluating devices used in nuclear power plant work environments. The U.S. Department of Energy Cf Loan/Lease Program, a longtime origin of affordable Cf sources for research, testing and calibration, was terminated in 2009. Since then, high-activity sources have become increasingly cost-prohibitive for laboratories that formerly benefited from that program. Neutron generators, based on the D-T and D-D fusion reactions, have become economically competitive with Cf and are recognized internationally as important calibration and test standards. Researchers from the National Institute of Standards and Technology and the Pacific Northwest National Laboratory are jointly considering the practicality and technical challenges of implementing neutron generators as calibration standards in the U.S. This article reviews the characteristics of isotope-based neutron sources, possible isotope alternatives to Cf, and the rationale behind the increasing favor of electronically generated neutron options. The evaluation of a D-T system at PNNL has revealed characteristics that must be considered in adapting generators to the task of calibration and testing where accurate determination of a dosimetric quantity is

  4. Ultrawideband radar echoes of land mine targets measured at oblique incidence using a 250-kW impulse radar system

    NASA Astrophysics Data System (ADS)

    Chant, Ian J.; Staines, Geoff

    1997-07-01

    United Nations Peacekeeping forces around the world need to transport food, personnel and medical supplies through disputed regions were land mines are in active use as road blocks and terror weapons. A method of fast, effective land mine detection is needed to combat this threat to road transport. The technique must operate from a vehicle travelling at a reasonable velocity and give warning far enough ahead for the vehicle to stop in time to avoid the land mine. There is particular interest in detecting low- metallic content land mines. One possible solutionis the use of ultra-wide-band (UWB) radar. The Australian Defence Department is investigating the feasibility of using UWB radar for land mine detection from a vehicle. A 3 GHz UWB system has been used to collect target response from a series of inert land mines and mine-like objects placed on the ground and buried in the ground. The targets measured were a subset of those in the target set described in Wong et al. with the addition of inert land mines corresponding to some of the surrogate targets in this set. The results are encouraging for the detection of metallic land mines and the larger non-metallic land mines. Smaller low-metallic- content anti-personnel land mines are less likely to be detected.

  5. A review of californium-252 neutron brachytherapy for cervical cancer

    SciTech Connect

    Maruyama, Y.; van Nagell, J.R.; Yoneda, J.; Donaldson, E.S.; Gallion, H.H.; Powell, D.; Kryscio, R.J. )

    1991-09-15

    Since 1976 a clinical trial has been conducted to test the feasibility, the potential, and to develop methods for using the neutron-emitting radioactive isotope, californium-252 (Cf-252), for the treatment of cervical cancer. A total of 218 patients were treated in the initial study period from 1976 until 1983. The trials initially treated advanced cervical cancer patients using different doses and schedules; they were extended to include unfavorable presentations of Stages 1 and 2 because of favorable results in the initial trials. The authors began to treat patients with Stage IB bulky or barrel-shaped tumors and the majority were treated with both radiation and hysterectomy. Actuarial survival was determined for Stage IB disease and was 87% at 5 years and 82% at 10 years. For those tested with preoperative radiation it was 92% at 5 and 87% at 10 years. For Stage 2, it was 62% 5 years and 61% at 10. Survival 5 years after combined radiation and surgical therapy for Stage 2 disease was 68%. For Stage 3, it was 33% at 5 years and 25% at 10. However, 5-year survival using the early neutron implant was 46% versus approximately 19% for delayed Cf-252 or cesium 137. Different schedules and sequences of neutrons and photons greatly altered outcome. Neutron treatment before external photon therapy was better for all stages of disease. Only about 5% of all patients developed complications after neutron therapy. No hematologic or mesenchymal second tumors were observed. Neutron brachytherapy was found to be very effective for producing rapid response and greatly improved local control of bulky, barrel, or advanced cervical cancers. The clinical trial identified and evolved schedules, doses, doses per session, and developed methods different from standard photon therapy but highly effective for local control and cure of cervical cancers of all stages.

  6. Remote afterloading for neutron brachytherapy using californium-252.

    PubMed

    Tacev, Taco; Grigorov, Grigor; Papírek, Tomás; Kolarík, Vladimír

    2003-02-01

    Despite a pronounced technical process attained in radiotherapy of malignant neoplasms, no remarkable improvement in the treatment results has been achieved. The reason for this stagnation is the interaction between tumor cell and photon radiation. Tumor resistance against photon bombardment can be broken down by applying high linear energy transfer (LET) radiation-based treatment. The discovery of californium-252 ((252)Cf) nuclide, a source of gamma neutron radiation, established a precondition for using neutrons in tumor brachytherapy. The design of a remote afterloading device using (252)Cf sources remains an unsolved problem. The afterloading device has been designed as a stationary radiator which is composed of three mutually interconnected units: 1. the control and drive unit consisting of a control computer and a motor-driven bowden system carrying the (252)Cf source; 2. the source which is housed in a watertight concrete vessel-storage strong room, situated in the ground at a depth of 25 cm beneath the patient's bed; 3. the afterloading application module installed in the irradiation room. Remote afterloading allows simple, inexpensive and highly efficient radiation protection and work safety for the operating personnel. The sources may be moved arbitrarily during treatment with a position accuracy of 0.5-1.0 mm within a distance of 520 cm from the source storage position in the strong room to the application position. Both afterloading systems' unused indexer outputs are protected electronically and mechanically against any unintentional movement of the source outside the application tubes. The technologic concept of the present automatic afterloading device for neutron brachytherapy represents a possible option from the range of conceivable design variants, which - while minimizing technologic and economic requirements - provides the operating personnel with optimum protection and work safety, thus extending the applicability of high LET radiation

  7. Electron collisional detachment processes for a 250 keV D- ion beam in a partially ionized hydrogen target

    NASA Astrophysics Data System (ADS)

    Savas, S. E.

    1981-08-01

    Neutral atom beams with energies above 200 keV are required for various purposes in magnetic fusion devices following TFTR, JET and MFTF-B. These beams are produced much more efficiently by electron detachment from negative ion beams than by electron capture by positive ions. The efficiency with which such neutral atoms can be produced by electron detachment in partially ionized hydrogen plasma neutralizers is investigated. Neutralization efficiencies for partially ionized hydrogen targets are calculated making use of cross sections. Previously calculated only for a pure electron gas neutralizer, this result was extended to conditions of arbitrary mixture of hydrogen gas and plasma using an averaging technique on the cross sections for the different target species. The effect of mixtures with contaminating gases and O2 and N2 on the neutralizer efficiency are also studied.

  8. Three-cluster model for the α-accompanied fission of californium nuclei

    NASA Astrophysics Data System (ADS)

    Manimaran, K.; Balasubramaniam, M.

    2009-02-01

    A three-cluster model is proposed to explain the particle-accompanied binary fission of radioactive nuclei. The model is developed as an extension of the preformed cluster model of Gupta and collaborators. The advantage of this model is that, for a fixed third fragment, we can calculate the fragmentation potential minimized in charge coordinate. For our study we chose the various neutron-deficient to neutron-rich californium nuclei, whose analysis reveals that the closed-shell effect of any one of the fragments in ternary fragmentation presents itself as the most favorable configuration to be observed. As one goes from a neutron-deficient to a neutron-rich californium isotope, the role of the neutron closed shell associated with any one of the preferred fragments changes to that of the proton closed shell, and for very neutron rich isotopes of californium the presence of a double closed shell nucleus enhances the decay probability. The quadrupole deformation of the light fragment (A2) associated with the preferred configuration in the symmetric mass region also has a transition from positive to negative deformation as one goes from neutron-deficient to neutron-rich californium isotopes. The calculated relative yields of different fragmentation channels are compared with the available experimental yields for Cf252.

  9. Three-cluster model for the {alpha}-accompanied fission of californium nuclei

    SciTech Connect

    Manimaran, K.; Balasubramaniam, M.

    2009-02-15

    A three-cluster model is proposed to explain the particle-accompanied binary fission of radioactive nuclei. The model is developed as an extension of the preformed cluster model of Gupta and collaborators. The advantage of this model is that, for a fixed third fragment, we can calculate the fragmentation potential minimized in charge coordinate. For our study we chose the various neutron-deficient to neutron-rich californium nuclei, whose analysis reveals that the closed-shell effect of any one of the fragments in ternary fragmentation presents itself as the most favorable configuration to be observed. As one goes from a neutron-deficient to a neutron-rich californium isotope, the role of the neutron closed shell associated with any one of the preferred fragments changes to that of the proton closed shell, and for very neutron rich isotopes of californium the presence of a double closed shell nucleus enhances the decay probability. The quadrupole deformation of the light fragment (A{sub 2}) associated with the preferred configuration in the symmetric mass region also has a transition from positive to negative deformation as one goes from neutron-deficient to neutron-rich californium isotopes. The calculated relative yields of different fragmentation channels are compared with the available experimental yields for {sup 252}Cf.

  10. Non-targeted whole genome 250K SNP array analysis as replacement for karyotyping in fetuses with structural ultrasound anomalies: evaluation of a one-year experience.

    PubMed

    Faas, Brigitte H W; Feenstra, Ilse; Eggink, Alex J; Kooper, Angelique J A; Pfundt, Rolph; van Vugt, John M G; de Leeuw, Nicole

    2012-04-01

    We evaluated both clinical and laboratory aspects of our new strategy offering quantitative fluorescence (QF)-PCR followed by non-targeted whole genome 250K single-nucleotide polymorphism array analysis instead of routine karyotyping for prenatal diagnosis of fetuses with structural anomalies. Upon the detection of structural fetal anomalies, parents were offered a choice between QF-PCR and 250K single-nucleotide polymorphism array analysis (QF/array) or QF-PCR and routine karyotyping (QF/karyo). Two hundred twenty fetal samples were included. In 153/220 cases (70%), QF/array analysis was requested. In 35/153 (23%), an abnormal QF-PCR result was found. The remaining samples were analyzed by array, which revealed clinically relevant aberrations, including two known microdeletions, in 5/118 cases. Inherited copy number variants were detected in 11/118 fetuses, copy number variants with uncertain clinical relevance in 3/118 and homozygous stretches in 2/118. In 67/220 (30%) fetuses, QF/karyo was requested: 23/67 (34%) were abnormal with QF-PCR, and in 3/67, an abnormal karyotype was found. Even though QF/array does not reveal a high percentage of submicroscopic aberrations in fetuses with unselected structural anomalies, it is preferred over QF/karyo, as it provides a whole genome scan at high resolution, without additional tests needed and with a low chance on findings not related to the ultrasound anomalies. © 2012 John Wiley & Sons, Ltd.

  11. Discovery of abundant cellulose microfibers encased in 250 Ma Permian halite: a macromolecular target in the search for life on other planets.

    PubMed

    Griffith, Jack D; Willcox, Smaranda; Powers, Dennis W; Nelson, Roger; Baxter, Bonnie K

    2008-04-01

    In this study, we utilized transmission electron microscopy to examine the contents of fluid inclusions in halite (NaCl) and solid halite crystals collected 650 m below the surface from the Late Permian Salado Formation in southeastern New Mexico (USA). The halite has been isolated from contaminating groundwater since deposition approximately 250 Ma ago. We show that abundant cellulose microfibers are present in the halite and appear remarkably intact. The cellulose is in the form of 5 nm microfibers as well as composite ropes and mats, and was identified by resistance to 0.5 N NaOH treatment and susceptibility to cellulase enzyme treatment. These cellulose microfibers represent the oldest native biological macromolecules to have been directly isolated, examined biochemically, and visualized (without growth or replication) to date. This discovery points to cellulose as an ideal macromolecular target in the search for life on other planets in our Solar System.

  12. Secondary particle yields from 400 MeV/u carbon ion and 250 MeV proton beams incident on thick targets

    NASA Astrophysics Data System (ADS)

    Ferrari, A.; Ferrarini, M.; Pelliccioni, M.

    2011-07-01

    The double differential particle yield produced by hadron beams striking thick targets of copper, tungsten and ICRU tissue, have been determined by means of the Monte Carlo transport code FLUKA (version FLUKA 2008.3b.1). 400 MeV/u carbon ion and 250 MeV proton pencil beams have been considered. Secondary neutrons, photons, and protons have been scored. In order to validate the obtained data, a few simulations have been also repeated with MCNPX 2.6.0. The calculated results are presented and compared with the experimental data reported in literature. They should be very useful to solve a number of problems related to technological aspects of hadrontherapy.

  13. Final report on Seed Money Project 3210-0346: Feasibility study for californium cold neutron source

    SciTech Connect

    Alsmiller, R.G.; Henderson, D.L.; Montgomery, B.H.

    1988-10-01

    A study has been completed of the feasibility and cost of building a cold neutron source that is not dependent on a reactor or accelerator. The neutron source is provided by up to ten /sup 252/Cf capsules, each containing 50 mg of the isotope produced in the High-Flux Isotope Reactor. The neutrons are moderated by heavy water and liquid deuterium to attain, in practice, a peak cold neutron flux of 1.4 /times/ 10/sup 13/ neutrons/(m/sup 2//center dot/s). The new facility would be located in the TURF Californium Facility. The estimated cost of the Californium Cold Neutron Source Facility is $6.5 million. 6 figs., 1 tab.

  14. Apparatus for the measurement of total body nitrogen using prompt neutron activation analysis with californium-252.

    PubMed

    Mackie, A; Hannan, W J; Smith, M A; Tothill, P

    1988-01-01

    Details of clinical apparatus designed for the measurement of total body nitrogen (as an indicator of body protein), suitable for the critically ill, intensive-care patient are presented. Californium-252 radio-isotopic neutron sources are used, enabling a nitrogen measurement by prompt neutron activation analysis to be made in 40 min with a precision of +/- 3.2% for a whole body dose equivalent of 0.145 mSv. The advantages of Californium-252 over alternative neutron sources are discussed. A comparison between two irradiation/detection geometries is made, leading to an explanation of the geometry adopted for the apparatus. The choice of construction and shielding materials to reduce the count rate at the detectors and consequently to reduce the pile-up contribution to the nitrogen background is discussed. Salient features of the gamma ray spectroscopy system to reduce spectral distortion from pulse pile-up are presented.

  15. Resolution concept for separation of curium from californium by ion-exchange chromatography.

    PubMed

    Aly, H F; Latimer, R M; Abdel-Rassoul, A A

    1970-04-01

    Different factors affecting separation of the tervalent actinides curium and californium by ion-exchange chromatography are discussed in the light of the resolution factor. The fact that resolution is inversely proportional to resin particle diameter and directly proportional to column length has been confirmed experimentally. The effects influencing resolution due to changes in flow-rate of the mobile phase used are dependent on resin particle diameter. Changes in temperature affect a number of variables influencing resolution.

  16. Safety Analysis Report for Packaging (SARP) of the Oak Ridge National Laboratory TRU Californium Shipping Container

    SciTech Connect

    Box, W.D.; Shappert, L.B.; Seagren, R.D.; Klima, B.B.; Jurgensen, M.C.; Hammond, C.R.; Watson, C.D.

    1980-01-01

    An analytical evaluation of the Oak Ridge National Laboratory TRU Californium Shipping Container was made in order to demonstrate its compliance with the regulations governing off-site shipment of packages that contain radioactive material. The evaluation encompassed five primary categories: structural integrity, thermal resistance, radiation shielding, nuclear criticality safety, and quality assurance. The results of this evaluation demonstrate that the container complies with the applicable regulations.

  17. Possible stabilization of the tetravalent oxidation state of berkelium and californium in acetonitrile with triphenylarsine oxide

    SciTech Connect

    Payne, G.F.; Peterson, J.R.

    1987-01-01

    It appears that we may have prepared Bk(IV) nitrate.nTPAs0 and Bk(IV) perchlorate.nTPAs0 complexes which formed the corresponding Cf(IV) complexes through the beta decay of Bk-249. Definitive proof should come from similar experiments with quantities of Bk-249 large enough to allow spectrophotometric detection of the characteristic f..-->..f transitions in these berkelium and californium species. It is clear, however, that TPAs0 and acetonitrile can play a pivotal role in the stabilization of lanact(IV) species.

  18. 10 CFR Appendix L to Part 110 - Illustrative List of Byproduct Materials Under NRC Export/Import Licensing Authority a

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Calcium 45 (Ca 45) Calcium 47 (Ca 47) Californium 248 (Cf 248) Californium 249 (Cf 249) Californium 250 (Cf 250) Californium 251 (Cf 251) Californium 252 (Cf 252) Californium 253 (Cf 253) Californium 254 (Cf 254) Carbon 14 (C 14) Cerium 141 (Ce 141) Cerium 143 (Ce 143) Cerium 144 (Ce 144) Cesium 131 (Cs...

  19. Californium-252 neutron brachytherapy combined with external pelvic radiotherapy plus concurrent chemotherapy for cervical cancer: a retrospective clinical study.

    PubMed

    Qian, Shen; Ye, Ling; Tian, Yun-Hong; Wang, Li-Gen; Huang, Zuo-Ping; Li, Feng; Hou, Bing; Song, Ni; Chen, Juan; Liu, Ying; Liu, Xiao; Zhou, Tao

    2017-02-28

    Cervical cancer is the sixth most common cancer in Chinese women. A standard treatment modality for cervical cancer is the combination of surgery, chemotherapy, external-beam radiotherapy and intracavitary brachytherapy. The aim of this study was to retrospectively assess the long-term treatment outcomes of patients with cervical cancer who were treated with californium-252 neutron brachytherapy combined with external-beam radiotherapy plus concurrent chemotherapy. We retrospectively analyzed the medical records of 150 patients with primary stages IB-IVB cervical cancer who received neutron brachytherapy combined with external-beam radiotherapy concurrently with cisplatin chemotherapy. All patients were followed up. Using an actuarial analysis, patient outcomes and treatment-related adverse effects were evaluated and compared. The median overall survival (OS) was 33.2 months. The 3-year progression-free survival rates for patients with stages I-II, III, and IV diseases were 81.0% (68/84), 65.0% (39/60), and 0% (0/6), respectively; the 3-year OS rates were 90.5% (76/84), 85.0% (51/60), and 16.7% (1/6), respectively. Vaginal bleeding was controlled within the median time of 4.0 days. One month after treatment, 97.3% of patients achieved short-term local control. The local recurrence rates for patients with stages I-II, III, and IV disease were 4.8% (4/84), 11.7% (7/60), and 33.3% (2/6), respectively, and the occurrence rates of distant metastasis were 16.7% (14/84), 25.0% (15/60), and 100.0% (6/6), respectively. Cancer stage, tumor size, and lymph node metastasis were identified as prognostic risk factors, but only lymph node metastasis was found to be an independent prognostic factor. The most common adverse effects during treatment were grades 1 and 2 irradiation-related proctitis and radiocystitis. For patients with cervical cancer, neutron brachytherapy combined with external-beam radiotherapy plus concurrent chemotherapy produces a rapid response and greatly

  20. First structural determination of a trivalent californium compound with oxygen coordination.

    PubMed

    Sykora, Richard E; Assefa, Zerihun; Haire, Richard G; Albrecht-Schmitt, Thomas E

    2006-01-23

    Single crystals of Cf(IO(3))(3) (1) were synthesized by the hydrothermal reaction of CfCl(3) and H(5)IO(6), and the structure was determined with single-crystal X-ray diffraction. This structural determination of 1 represents the first for a trivalent californium compound containing oxygen coordination. This compound has been further characterized with the use of Raman spectroscopy and emission spectroscopy. Crystallographic data: Cf(IO(3))(3), monoclinic, space group P2(1)/n, a = 8.7994(10) A, b = 5.9388(7) A, c = 15.157(2) A, beta = 96.833(2) degrees , V = 786.43(16) A(3), Z = 4 (T = 295 K).

  1. Production of new superheavy Z=108-114 nuclei with {sup 238}U, {sup 244}Pu, and {sup 248,250}Cm targets

    SciTech Connect

    Feng Zhaoqing; Jin Genming; Li Junqing

    2009-11-15

    Within the framework of the dinuclear system (DNS) model, production cross sections of new superheavy nuclei with charged numbers Z=108-114 are analyzed systematically. Possible combinations based on the actinide nuclides {sup 238}U, {sup 244}Pu, and {sup 248,250}Cm with the optimal excitation energies and evaporation channels are pointed out to synthesize new isotopes that lie between the nuclides produced in the cold fusion reactions and the {sup 48}Ca-induced fusion reactions experimentally, which are feasible to be constructed experimentally. It is found that the production cross sections of superheavy nuclei decrease drastically with the charged numbers of compound nuclei. Larger mass asymmetries of the entrance channels enhance the cross sections in 2n-5n channels.

  2. Phase I-II clinical trial of Californium-252. Treatment of stage IB carcinoma of the cervix.

    PubMed

    Maruyama, Y; VanNagell, J R; Yoneda, J; Donaldson, E; Gallion, H; Rowley, K; Kryscio, R; Beach, J L

    1987-04-15

    Intracavitary Californium-252 combined with whole-pelvis photon radiotherapy was tested as the sole form of treatment for 22 patients with Stage IB carcinoma of the cervix. Californium-252 (Cf) is a fast neutron-emitting radioisotope currently being tested in trials of neutron brachytherapy (NT). The outcomes of the treated group of patients were traced for local tumor control, survival, patterns of failure, and complications. The Cf intracavitary therapy combined with whole-pelvis photon radiotherapy resulted in 95% 2-year and 91% 5-year actuarial survival. There were 9% Grade II-III complications by the Stockholm scale and 4% local failures. These results were obtained in an early clinical trial with a group of largely poor-risk patients with tumors of mean diameter of 4.3 cm.

  3. Phase I-II clinical trial of Californium-252. Treatment of stage IB carcinoma of the cervix

    SciTech Connect

    Maruyama, Y.; VanNagell, J.R.; Yoneda, J.; Donaldson, E.; Gallion, H.; Rowley, K.; Kryscio, R.; Beach, J.L.

    1987-04-15

    Intracavitary Californium-252 combined with whole-pelvis photon radiotherapy was tested as the sole form of treatment for 22 patients with Stage IB carcinoma of the cervix. Californium-252 (Cf) is a fast neutron-emitting radioisotope currently being tested in trials of neutron brachytherapy (NT). The outcomes of the treated group of patients were traced for local tumor control, survival, patterns of failure, and complications. The Cf intracavitary therapy combined with whole-pelvis photon radiotherapy resulted in 95% 2-year and 91% 5-year actuarial survival. There were 9% Grade II-III complications by the Stockholm scale and 4% local failures. These results were obtained in an early clinical trial with a group of largely poor-risk patients with tumors of mean diameter of 4.3 cm.

  4. Design of the injection beamline for the Californium Rare Isotope Breeder Upgrade electron beam ion source for charge breeder

    SciTech Connect

    Dickerson C. A.; Pikin A.; Mustapha, B.; Kondrashev, S.; Ostroumov, P.N.; Savard, S.; Levand, A.

    2012-02-07

    The design of the ion injection line connecting the electron beam ion source (EBIS) charge breeder and the Californium Rare Isotope Breeder Upgrade radio frequency quadrupole cooler-buncher at the Argonne Tandem Linear Accelerator System was investigated with particle tracking simulations. The injection line was configured to accommodate several differential pumping sections, individual optical components were optimized to minimize emittance growth, and the ion beam parameters were matched with the EBIS electron beam acceptance to minimize losses upon injection.

  5. Design of the injection beamline for the Californium Rare Isotope Breeder Upgrade electron beam ion source charge breeder

    SciTech Connect

    Dickerson, C. A.; Mustapha, B.; Kondrashev, S.; Ostroumov, P. N.; Savard, G.; Levand, A.; Pikin, A.

    2012-02-15

    The design of the ion injection line connecting the electron beam ion source (EBIS) charge breeder and the Californium Rare Isotope Breeder Upgrade radio frequency quadrupole cooler-buncher at the Argonne Tandem Linear Accelerator System was investigated with particle tracking simulations. The injection line was configured to accommodate several differential pumping sections, individual optical components were optimized to minimize emittance growth, and the ion beam parameters were matched with the EBIS electron beam acceptance to minimize losses upon injection.

  6. Design of the injection beamline for the Californium Rare Isotope Breeder Upgrade electron beam ion source charge breedera)

    NASA Astrophysics Data System (ADS)

    Dickerson, C. A.; Mustapha, B.; Kondrashev, S.; Ostroumov, P. N.; Savard, G.; Levand, A.; Pikin, A.

    2012-02-01

    The design of the ion injection line connecting the electron beam ion source (EBIS) charge breeder and the Californium Rare Isotope Breeder Upgrade radio frequency quadrupole cooler-buncher at the Argonne Tandem Linear Accelerator System was investigated with particle tracking simulations. The injection line was configured to accommodate several differential pumping sections, individual optical components were optimized to minimize emittance growth, and the ion beam parameters were matched with the EBIS electron beam acceptance to minimize losses upon injection.

  7. Design of the injection beamline for the Californium Rare Isotope Breeder Upgrade electron beam ion source charge breeder.

    PubMed

    Dickerson, C A; Mustapha, B; Kondrashev, S; Ostroumov, P N; Savard, G; Levand, A; Pikin, A

    2012-02-01

    The design of the ion injection line connecting the electron beam ion source (EBIS) charge breeder and the Californium Rare Isotope Breeder Upgrade radio frequency quadrupole cooler-buncher at the Argonne Tandem Linear Accelerator System was investigated with particle tracking simulations. The injection line was configured to accommodate several differential pumping sections, individual optical components were optimized to minimize emittance growth, and the ion beam parameters were matched with the EBIS electron beam acceptance to minimize losses upon injection.

  8. Convenient method of simultaneously analyzing aluminum and magnesium in pharmaceutical dosage forms using californium-252 thermal neutron activation.

    PubMed

    Landolt, R R; Hem, S L

    1983-05-01

    A commercial antacid suspension containing aluminum hydroxide and magnesium hydroxide products was used as a model sample to study the use of a californium-252 thermal neutron activation as a method for quantifying aluminum content as well as for the simultaneous assay of aluminum and magnesium. A 3.5-micrograms californium-252 source was used for the activation, and the induced aluminum-28 and magnesium-27 activity was simultaneously measured by sodium iodide crystal gamma-ray spectrometry using dual single-channel analyzers and scalers. The antacid suspension was contained in a chamber designed with the unique capability of serving as the container for counting the induced radioactivity in addition to being the irradiation chamber itself. Ten replicate irradiations were performed, and the precision was compared with 10 replicate analyses of the antacid suspension using the official ethylenediaminetetraacetic acid titration method. For aluminum the precision was 1.4 versus 0.62% for the titration method. For the magnesium the precision was 5.3 versus 0.79% for the titration method. This pilot study demonstrated that use of more intense californium-252 sources, which are commonly available, would provide a method that is competitive with the ethylenediaminetetraacetic acid titration method in precision and in other aspects as well.

  9. 30 CFR 250.507-250.508 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false 250.507-250.508 Section 250.507-250.508 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations §§ 250.507-250.508 ...

  10. 18 CFR 250.7-250.15 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false 250.7-250.15 Section 250.7-250.15 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.7-250.15 ...

  11. 18 CFR 250.1-250.5 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false 250.1-250.5 Section 250.1-250.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.1—250.5 ...

  12. 30 CFR 250.1921-250.1923 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Environmental Management Systems (SEMS) §§ 250.1921-250.1923 ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false 250.1921-250.1923 Section 250.1921-250.1923 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE...

  13. 30 CFR 250.1905-250.1908 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Environmental Management Systems (SEMS) §§ 250.1905-250.1908 ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false 250.1905-250.1908 Section 250.1905-250.1908 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE...

  14. 18 CFR 250.7-250.15 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false 250.7-250.15 Section 250.7-250.15 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.7-250.15 ...

  15. 18 CFR 250.7-250.15 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false 250.7-250.15 Section 250.7-250.15 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.7-250.15 ...

  16. 18 CFR 250.7-250.15 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false 250.7-250.15 Section 250.7-250.15 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.7-250.15 ...

  17. 18 CFR 250.1-250.5 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false 250.1-250.5 Section 250.1-250.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.1-250.5 ...

  18. 18 CFR 250.1-250.5 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false 250.1-250.5 Section 250.1-250.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.1-250.5 ...

  19. 18 CFR 250.1-250.5 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false 250.1-250.5 Section 250.1-250.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.1-250.5 ...

  20. 18 CFR 250.7-250.15 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false 250.7-250.15 Section 250.7-250.15 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.7-250.15 ...

  1. 18 CFR 250.1-250.5 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false 250.1-250.5 Section 250.1-250.5 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY APPROVED FORMS, NATURAL GAS ACT FORMS §§ 250.1—250.5 ...

  2. 17 CFR 250.106-250.107 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false 250.106-250.107 Section 250.106-250.107 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Miscellaneous Rules §§ 250.106-250.107...

  3. 30 CFR 250.607-250.608 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false 250.607-250.608 Section 250.607-250.608 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations §§ 250.607-250.608...

  4. 48 CFR 952.250-71-952.250-72 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false 952.250-71-952.250-72 Section 952.250-71-952.250-72 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.250-71—952.250-72...

  5. 30 CFR 250.507-250.508 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false 250.507-250.508 Section 250.507-250.508 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations §§ 250...

  6. 30 CFR 250.507-250.508 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false 250.507-250.508 Section 250.507-250.508 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations §§ 250...

  7. 30 CFR 250.507-250.508 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false 250.507-250.508 Section 250.507-250.508 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations §§ 250...

  8. Fast and efficient charge breeding of the Californium rare isotope breeder upgrade electron beam ion source

    NASA Astrophysics Data System (ADS)

    Ostroumov, P. N.; Barcikowski, A.; Dickerson, C. A.; Perry, A.; Pikin, A. I.; Sharamentov, S. I.; Vondrasek, R. C.; Zinkann, G. P.

    2015-08-01

    The Electron Beam Ion Source (EBIS), developed to breed Californium Rare Isotope Breeder Upgrade (CARIBU) radioactive beams at Argonne Tandem Linac Accelerator System (ATLAS), is being tested off-line. A unique property of the EBIS is a combination of short breeding times, high repetition rates, and a large acceptance. Overall, we have implemented many innovative features during the design and construction of the CARIBU EBIS as compared to the existing EBIS breeders. The off-line charge breeding tests are being performed using a surface ionization source that produces singly charged cesium ions. The main goal of the off-line commissioning is to demonstrate stable operation of the EBIS at a 10 Hz repetition rate and a breeding efficiency into single charge state higher than 15%. These goals have been successfully achieved and exceeded. We have measured (20% ± 0.7%) breeding efficiency into the single charge state of 28+ cesium ions with the breeding time of 28 ms. In general, the current CARIBU EBIS operational parameters can provide charge breeding of any ions in the full mass range of periodic table with high efficiency, short breeding times, and sufficiently low charge-to-mass ratio, 1/6.3 for the heaviest masses, for further acceleration in ATLAS. In this paper, we discuss the parameters of the EBIS and the charge breeding results in a pulsed injection mode with repetition rates up to 10 Hz.

  9. Reaction Rate Measurement at the Californium User Facility (CUF) for unfolding the neutron spectrum

    NASA Astrophysics Data System (ADS)

    Hannan, Mohammad; Ortega, Ruben

    2011-03-01

    Neutron Activation Analysis was used to determine Reaction Rate measurement of several activation detectors at the ORNL Californium User Facility (CUF). The irradiations were performed with 34 mg Cf 252 neutron source strength.. Ten source capsules > 34 mgwerepositionedconcentricallyaroundasamplecavity . Wehavedeterminedabsoluteactivityperatomof 9 detectors : Au 197 (n , γ) Au 198 , Al 27 (n , α) Na 24 , Al 27 (n , p) Mg 27 , Fe 56 (n , p) Mn 5 , Fe 54 (n , p) Mn 54 , In 115 (n , γ) In 116 , Ti 46 (n , p) Sc 46 , Ni 60 (n , p) Co 60 , Fe 58 (n , γ) Fe 59 . Theerrorsarewithin 1.5 - 8 60 and Fe 58 have errors of 46% and 32 %. These high errors may be attributed to the counting statistics. These reaction rate values will be used to unfold the neutron spectrum of the CUF using the MAXED 2000, a computer code for the de convolution of multi sphere neutron spectrometer data and the results are discussed. The authors acknowledge help, advise, and using facility at ORNL-CUF to Dr. Rodger martin and Mr. David C. Galsgow.

  10. Fast and efficient charge breeding of the Californium rare isotope breeder upgrade electron beam ion source.

    PubMed

    Ostroumov, P N; Barcikowski, A; Dickerson, C A; Perry, A; Pikin, A I; Sharamentov, S I; Vondrasek, R C; Zinkann, G P

    2015-08-01

    The Electron Beam Ion Source (EBIS), developed to breed Californium Rare Isotope Breeder Upgrade (CARIBU) radioactive beams at Argonne Tandem Linac Accelerator System (ATLAS), is being tested off-line. A unique property of the EBIS is a combination of short breeding times, high repetition rates, and a large acceptance. Overall, we have implemented many innovative features during the design and construction of the CARIBU EBIS as compared to the existing EBIS breeders. The off-line charge breeding tests are being performed using a surface ionization source that produces singly charged cesium ions. The main goal of the off-line commissioning is to demonstrate stable operation of the EBIS at a 10 Hz repetition rate and a breeding efficiency into single charge state higher than 15%. These goals have been successfully achieved and exceeded. We have measured (20% ± 0.7%) breeding efficiency into the single charge state of 28+ cesium ions with the breeding time of 28 ms. In general, the current CARIBU EBIS operational parameters can provide charge breeding of any ions in the full mass range of periodic table with high efficiency, short breeding times, and sufficiently low charge-to-mass ratio, 1/6.3 for the heaviest masses, for further acceleration in ATLAS. In this paper, we discuss the parameters of the EBIS and the charge breeding results in a pulsed injection mode with repetition rates up to 10 Hz.

  11. Fast and efficient charge breeding of the Californium rare isotope breeder upgrade electron beam ion source

    DOE PAGES

    Ostroumov, P. N.; Barcikowski, A.; Dickerson, C. A.; ...

    2015-08-28

    The Electron Beam Ion Source (EBIS), developed to breed Californium Rare Isotope Breeder Upgrade (CARIBU) radioactive beams at Argonne Tandem Linac Accelerator System (ATLAS), is being tested off-line. A unique property of the EBIS is a combination of short breeding times, high repetition rates, and a large acceptance. Overall, we have implemented many innovative features during the design and construction of the CARIBU EBIS as compared to the existing EBIS breeders. The off-line charge breeding tests are being performed using a surface ionization source that produces singly charged cesium ions. The main goal of the off-line commissioning is to demonstratemore » stable operation of the EBIS at a 10 Hz repetition rate and a breeding efficiency into single charge state higher than 15%. These goals have been successfully achieved and exceeded. We have measured (20% ± 0.7%) breeding efficiency into the single charge state of 28+ cesium ions with the breeding time of 28 ms. In general, the current CARIBU EBIS operational parameters can provide charge breeding of any ions in the full mass range of periodic table with high efficiency, short breeding times, and sufficiently low charge-to-mass ratio, 1/6.3 for the heaviest masses, for further acceleration in ATLAS. In this study, we discuss the parameters of the EBIS and the charge breeding results in a pulsed injection mode with repetition rates up to 10 Hz.« less

  12. Fast and efficient charge breeding of the Californium rare isotope breeder upgrade electron beam ion source

    SciTech Connect

    Ostroumov, P. N. Barcikowski, A.; Dickerson, C. A.; Perry, A.; Sharamentov, S. I.; Vondrasek, R. C.; Zinkann, G. P.; Pikin, A. I.

    2015-08-15

    The Electron Beam Ion Source (EBIS), developed to breed Californium Rare Isotope Breeder Upgrade (CARIBU) radioactive beams at Argonne Tandem Linac Accelerator System (ATLAS), is being tested off-line. A unique property of the EBIS is a combination of short breeding times, high repetition rates, and a large acceptance. Overall, we have implemented many innovative features during the design and construction of the CARIBU EBIS as compared to the existing EBIS breeders. The off-line charge breeding tests are being performed using a surface ionization source that produces singly charged cesium ions. The main goal of the off-line commissioning is to demonstrate stable operation of the EBIS at a 10 Hz repetition rate and a breeding efficiency into single charge state higher than 15%. These goals have been successfully achieved and exceeded. We have measured (20% ± 0.7%) breeding efficiency into the single charge state of 28+ cesium ions with the breeding time of 28 ms. In general, the current CARIBU EBIS operational parameters can provide charge breeding of any ions in the full mass range of periodic table with high efficiency, short breeding times, and sufficiently low charge-to-mass ratio, 1/6.3 for the heaviest masses, for further acceleration in ATLAS. In this paper, we discuss the parameters of the EBIS and the charge breeding results in a pulsed injection mode with repetition rates up to 10 Hz.

  13. Neutron activation analysis at the Californium User Facility for Neutron Science

    SciTech Connect

    Martin, R.C.; Smith, E.H.; Glasgow, D.C.; Jerde, E.A.; Marsh, D.L.; Zhao, L.

    1997-12-01

    The Californium User Facility (CUF) for Neutron Science has been established to provide {sup 252}Cf-based neutron irradiation services and research capabilities including neutron activation analysis (NAA). A major advantage of the CUF is its accessibility and controlled experimental conditions compared with those of a reactor environment The CUF maintains the world`s largest inventory of compact {sup 252}Cf neutron sources. Neutron source intensities of {le} 10{sup 11} neutrons/s are available for irradiations within a contamination-free hot cell, capable of providing thermal and fast neutron fluxes exceeding 10{sup 8} cm{sup {minus}2} s{sup {minus}1} at the sample. Total flux of {ge}10{sup 9} cm{sup {minus}2} s{sup {minus}1} is feasible for large-volume irradiation rabbits within the {sup 252}Cf storage pool. Neutron and gamma transport calculations have been performed using the Monte Carlo transport code MCNP to estimate irradiation fluxes available for sample activation within the hot cell and storage pool and to design and optimize a prompt gamma NAA (PGNAA) configuration for large sample volumes. Confirmatory NAA irradiations have been performed within the pool. Gamma spectroscopy capabilities including PGNAA are being established within the CUF for sample analysis.

  14. Fast and efficient charge breeding of the Californium rare isotope breeder upgrade electron beam ion source

    SciTech Connect

    Ostroumov, P. N.; Barcikowski, A.; Dickerson, C. A.; Perry, A.; Pikin, A. I.; Sharamentov, S. I.; Vondrasek, R. C.; Zinkann, G. P.

    2015-08-28

    The Electron Beam Ion Source (EBIS), developed to breed Californium Rare Isotope Breeder Upgrade (CARIBU) radioactive beams at Argonne Tandem Linac Accelerator System (ATLAS), is being tested off-line. A unique property of the EBIS is a combination of short breeding times, high repetition rates, and a large acceptance. Overall, we have implemented many innovative features during the design and construction of the CARIBU EBIS as compared to the existing EBIS breeders. The off-line charge breeding tests are being performed using a surface ionization source that produces singly charged cesium ions. The main goal of the off-line commissioning is to demonstrate stable operation of the EBIS at a 10 Hz repetition rate and a breeding efficiency into single charge state higher than 15%. These goals have been successfully achieved and exceeded. We have measured (20% ± 0.7%) breeding efficiency into the single charge state of 28+ cesium ions with the breeding time of 28 ms. In general, the current CARIBU EBIS operational parameters can provide charge breeding of any ions in the full mass range of periodic table with high efficiency, short breeding times, and sufficiently low charge-to-mass ratio, 1/6.3 for the heaviest masses, for further acceleration in ATLAS. In this study, we discuss the parameters of the EBIS and the charge breeding results in a pulsed injection mode with repetition rates up to 10 Hz.

  15. Clinical report on external irradiation combined with californium-252 neutron intraluminal brachytherapy for cervical carcinoma treatment.

    PubMed

    Zhao, Huanyu; Wang, Keming; Sun, Jian; Geng, Xin; Zhang, Weiming

    2007-01-01

    Neutron rays produce high linear energy transfer radiation, which has particular radiobiological characteristics. The aim of the study was to observe the curative effects and complications of external irradiation combined with californium-252 (252Cf) neutron intraluminal brachytherapy for treatment of cervical carcinoma. From December 2000 to December 2004, 128 cases of cervical carcinoma staged IIA to IIIB were treated with 252Cf neutron intraluminal brachytherapy using 8-10 Gy-eq per fraction, once a week. The total dose at reference point A was 36-40 Gy-eq in 4 to 5 fractions. From the second day after 252Cf neutron intraluminal brachytherapy, the whole pelvic cavity was treated with 6 MV X-ray external irradiation, applying 2 Gy per fraction 4 times per week. After 20-24 Gy of external irradiation, the center of the whole pelvic field was blocked with a 4-cm-wide lead shield; the total dose of external irradiation was 44-50 Gy. The short-term curative effects were 95.3% complete remissions and 4.7% partial remissions. The 3-year and 5-year local control rates were 93.5% and 87.9%, respectively. The 3-year and 5-year survival rates were 87.5% and 70%, respectively. The rates of radiation complications were 4.7% for radiation cystitis, 7.8% for radiation proctitis, 6.3% for vaginal contracture and adhesion, and 5.5% for protracted radiation proctitis. The results of univariate and multivariate analysis indicated that differentiation of tumor cells and lymphatic metastasis are the main factors related to the clinical prognosis of cervical carcinoma. A combination of external irradiation with 252Cf neutron intraluminal brachytherapy for treatment of cervical carcinoma can be well tolerated by patients. The rate of local tumor control is high and radiation complications are few.

  16. [The preliminary report of cervical cancer treated with californium-252 neutron after loading intracavitary radiotherapy].

    PubMed

    Luo, G; Zheng, C; Shan, J

    2001-12-01

    To observe the therapeutic effectiveness and complications of californium-252 (252Cf) brachytherapy in cervical cancer. Fifty one cases of cervical cancer were diagnosed according to the standard of the International Federation of Gynecology and Obstetrics (FIGO), II a:8 cases, II b:31 cases, III a:8 cases, III b:4 cases. Treatment schedule: 252Cf after loading brachytherapy, 10-12 Gy/fraction/week, the total dose of reference point A was 36-40 Gy in three to four implant sessions. In the second day after 252Cf therapy, the whole pelvis was treated with 6 MV X-ray external beam radiotherapy, 200 cGy per fraction, 4 times per week. The total dose of external beam radiotherapy was 40 to 50 Gy (the middle of pelvis was blocked at width of 4 cm after 20-30 Gy), then the total dose of reference point B was 50-55 Gy;the total treatment time was 5-6 weeks. The average time of complete tumor regression was 25 days, the local control rate of 2 year was 100%, the total 2 year survival rate was 92%, i.e., II a: 8/8 cases, II b: 30/31 cases (97%), III a: 6/8 cases, III b: 3/4 cases; the late radiation complications of bladder and rectum was 2% respectively during these 2 years. It is concluded that combined 252 Cf brachytherapy and high energy X-ray external beam radiotherapy may be safe and effective in the management of cervical cancer. 252Cf has advantages of high local control rate; rapidly regression of bulky tumors and low-grade radiation complications.

  17. 21 CFR 250.106-250.107 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false 250.106-250.107 Section 250.106-250.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL SPECIAL REQUIREMENTS FOR SPECIFIC HUMAN DRUGS New Drug or Prescription Status of Specific Drugs §§...

  18. 21 CFR 250.103-250.104 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false 250.103-250.104 Section 250.103-250.104 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL SPECIAL REQUIREMENTS FOR SPECIFIC HUMAN DRUGS New Drug or Prescription Status of Specific Drugs §§...

  19. 30 CFR 250.1905-250.1908 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false 250.1905-250.1908 Section 250.1905-250.1908 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management...

  20. 30 CFR 250.1905-250.1908 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false 250.1905-250.1908 Section 250.1905-250.1908 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management...

  1. 30 CFR 250.1921-250.1923 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false 250.1921-250.1923 Section 250.1921-250.1923 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management...

  2. 30 CFR 250.1905-250.1908 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false 250.1905-250.1908 Section 250.1905-250.1908 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management...

  3. 30 CFR 250.507-250.508 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false 250.507-250.508 Section 250.507-250.508 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas...

  4. 30 CFR 250.607-250.608 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false 250.607-250.608 Section 250.607-250.608 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas...

  5. Clinical assessment of 252Californium neutron intracavitary brachytherapy using a two-channel Y applicator combined with external beam radiotherapy for endometrial cancer

    PubMed Central

    Zhou, Qian; Cheng Tang; Zhao, Ke-Wei; Xiong, Yan-Li; Chen, Shu; Xu, Wen-Jing; Lei, Xin

    2016-01-01

    OBJECTIVE: The aim of this study was to determine the efficacy of 252Californium neutron intracavitary brachytherapy using a two-channel Y applicator combined with external beam radiotherapy for the treatment of endometrial cancer. METHODS: Thirty-one patients with stage I–III endometrial cancer were recruited for this study. The stage I patients received only 252Californium neutron intracavitary brachytherapy with a two-channel applicator. The stage II and III patients received both 252Californium neutron intracavitary brachytherapy using a two-channel applicator and parallel-opposed whole pelvic radiotherapy. RESULTS: The five-year local control rate was 80.6% (25/31), the overall survival rate was 51.6% (16/31), and the disease-free survival rate was 54.8% (17/31). The incidence of serious late complications was 12.9% (4/31). CONCLUSIONS: 252Californium neutron intracavitary brachytherapy using a two-channel applicator combined with external beam radiotherapy was effective for treating endometrial cancer and the incidence of serious late complications related to this combination was within an acceptable range. PMID:26872078

  6. Clinical assessment of 252Californium neutron intracavitary brachytherapy using a two-channel Y applicator combined with external beam radiotherapy for endometrial cancer.

    PubMed

    Zhou, Qian; Tang, Cheng; Zhao, Ke-Wei; Xiong, Yan-Li; Chen, Shu; Xu, Wen-Jing; Lei, Xin

    2016-01-01

    The aim of this study was to determine the efficacy of 252Californium neutron intracavitary brachytherapy using a two-channel Y applicator combined with external beam radiotherapy for the treatment of endometrial cancer. Thirty-one patients with stage I-III endometrial cancer were recruited for this study. The stage I patients received only 252Californium neutron intracavitary brachytherapy with a two-channel applicator. The stage II and III patients received both 252Californium neutron intracavitary brachytherapy using a two-channel applicator and parallel-opposed whole pelvic radiotherapy. The five-year local control rate was 80.6% (25/31), the overall survival rate was 51.6% (16/31), and the disease-free survival rate was 54.8% (17/31). The incidence of serious late complications was 12.9% (4/31). 252Californium neutron intracavitary brachytherapy using a two-channel applicator combined with external beam radiotherapy was effective for treating endometrial cancer and the incidence of serious late complications related to this combination was within an acceptable range.

  7. Divalent and trivalent gas-phase coordination complexes of californium: evaluating the stability of Cf(ii).

    PubMed

    Dau, Phuong D; Shuh, David K; Sturzbecher-Hoehne, Manuel; Abergel, Rebecca J; Gibson, John K

    2016-08-02

    The divalent oxidation state is increasingly stable relative to the trivalent state for the later actinide elements, with californium the first actinide to exhibit divalent chemistry under moderate conditions. Although there is evidence for divalent Cf in solution and solid compounds, there are no reports of discrete complexes in which Cf(II) is coordinated by anionic ligands. Described here is the divalent Cf methanesulfinate coordination complex, Cf(II)(CH3SO2)3(-), prepared in the gas phase by reductive elimination of CH3SO2 from Cf(III)(CH3SO2)4(-). Comparison with synthesis of the corresponding Sm and Cm complexes reveals reduction of Cf(III) and Sm(III), and no evidence for reduction of Cm(III). This reflects the comparative 3+/2+ reduction potentials: Cf(3+) (-1.60 V) ≈ Sm(3+) (-1.55 V) ≫ Cm(3+) (-3.7 V). Association of O2 to the divalent complexes is attributed to formation of superoxides, with recovery of the trivalent oxidation state. The new gas-phase chemistry of californium, now the heaviest element to have been studied in this manner, provides evidence for Cf(II) coordination complexes and similar chemistry of Cf and Sm.

  8. Simulation and design of an electron beam ion source charge breeder for the californium rare isotope breeder upgrade

    NASA Astrophysics Data System (ADS)

    Dickerson, Clayton; Mustapha, Brahim; Pikin, Alexander; Kondrashev, Sergey; Ostroumov, Peter; Levand, Anthony; Fischer, Rick

    2013-02-01

    An electron beam ion source (EBIS) will be constructed and used to charge breed ions from the californium rare isotope breeder upgrade (CARIBU) for postacceleration into the Argonne tandem linear accelerator system (ATLAS). Simulations of the EBIS charge breeder performance and the related ion transport systems are reported. Propagation of the electron beam through the EBIS was verified, and the anticipated incident power density within the electron collector was identified. The full normalized acceptance of the charge breeder with a 2 A electron beam, 0.024πmmmrad for nominal operating parameters, was determined by simulating ion injection into the EBIS. The optics of the ion transport lines were carefully optimized to achieve well-matched ion injection, to minimize emittance growth of the injected and extracted ion beams, and to enable adequate testing of the charge bred ions prior to installation in ATLAS.

  9. Californium-252 Brachytherapy Combined With External-Beam Radiotherapy for Cervical Cancer: Long-Term Treatment Results

    SciTech Connect

    Lei Xin; Qian Chengyuan; Qing Yi; Zhao Kewei; Yang Zhengzhou; Dai Nan; Zhong Zhaoyang; Tang Cheng; Li Zheng; Gu Xianqing; Zhou Qian; Feng Yan; Xiong Yanli; Shan Jinlu; Wang Dong

    2011-12-01

    Purpose: To observe, by retrospective analysis, the curative effects and complications due to californium-252 ({sup 252}Cf) neutron intracavitary brachytherapy (ICBT) combined with external-beam radiotherapy (EBRT) in the treatment of cervical cancer. Methods and Materials: From February 1999 to December 2007, 696 patients with cervical cancer (Stages IB to IIIB) were treated with {sup 252}Cf-ICBT in combination of EBRT. Of all, 31 patients were at Stage IB, 104 at IIA, 363 at IIB, 64 at IIIA, and 134 at IIIB. Californium-252 ICBT was delivered at 7-12 Gy per insertion per week, with a total dose of 29-45 Gy to reference point A in three to five insertions. The whole pelvic cavity was treated with 8-MV X-ray external irradiation at 2 Gy per fraction, four times per week. After 16-38 Gy of external irradiation, the center of the whole pelvic field was blocked with a 4-cm-wide lead shield, with a total external irradiation dose of 44-56 Gy. The total treatment course was 5 to 6 weeks. Results: Overall survival rate at 3 and 5 years for all patients was 76.0% and 64.9%, respectively. Disease-free 3- and 5-year survival rates of patients were 71.2% and 58.4%, respectively. Late complications included vaginal contracture and adhesion, radiation proctitis, radiation cystitis, and inflammatory bowel, which accounted for 5.8%, 7.1%, 6.2%, and 4.9%, respectively. Univariate analysis results showed significant correlation of stage, age, histopathologic grade, and lymph node status with overall survival. Cox multiple regression analysis showed that the independent variables were stage, histopathologic grade, tumor size, and lymphatic metastasis in all patients. Conclusion: Results of this series suggest that the combined use of {sup 252}Cf-ICBT with EBRT is an effective method for treatment of cervical cancer.

  10. Californium-252 brachytherapy combined with external-beam radiotherapy for cervical cancer: long-term treatment results.

    PubMed

    Lei, Xin; Qian, Cheng-Yuan; Qing, Yi; Zhao, Ke-Wei; Yang, Zheng-Zhou; Dai, Nan; Zhong, Zhao-Yang; Tang, Cheng; Li, Zheng; Gu, Xian-Qing; Zhou, Qian; Feng, Yan; Xiong, Yan-Li; Shan, Jin-Lu; Wang, Dong

    2011-12-01

    To observe, by retrospective analysis, the curative effects and complications due to californium-252 (252Cf) neutron intracavitary brachytherapy (ICBT) combined with external-beam radiotherapy (EBRT) in the treatment of cervical cancer. From February 1999 to December 2007, 696 patients with cervical cancer (Stages IB to IIIB) were treated with 252Cf-ICBT in combination of EBRT. Of all, 31 patients were at Stage IB, 104 at IIA, 363 at IIB, 64 at IIIA, and 134 at IIIB. Californium-252 ICBT was delivered at 7-12 Gy per insertion per week, with a total dose of 29-45 Gy to reference point A in three to five insertions. The whole pelvic cavity was treated with 8-MV X-ray external irradiation at 2 Gy per fraction, four times per week. After 16-38 Gy of external irradiation, the center of the whole pelvic field was blocked with a 4-cm-wide lead shield, with a total external irradiation dose of 44-56 Gy. The total treatment course was 5 to 6 weeks. Overall survival rate at 3 and 5 years for all patients was 76.0% and 64.9%, respectively. Disease-free 3- and 5-year survival rates of patients were 71.2% and 58.4%, respectively. Late complications included vaginal contracture and adhesion, radiation proctitis, radiation cystitis, and inflammatory bowel, which accounted for 5.8%, 7.1%, 6.2%, and 4.9%, respectively. Univariate analysis results showed significant correlation of stage, age, histopathologic grade, and lymph node status with overall survival. Cox multiple regression analysis showed that the independent variables were stage, histopathologic grade, tumor size, and lymphatic metastasis in all patients. Results of this series suggest that the combined use of 252Cf-ICBT with EBRT is an effective method for treatment of cervical cancer. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. From ANAIS-25 towards ANAIS-250

    NASA Astrophysics Data System (ADS)

    Amaré, J.; Cebrián, S.; Cuesta, C.; García, E.; Ginestra, C.; Martínez, M.; Oliván, M. A.; Ortigoza, Y.; Solórzano, A. Ortiz de; Pobes, C.; Puimedón, J.; Sarsa, M. L.; Villar, J. A.; Villar, P.

    The ANAIS (Annual modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory (LSC). 250 kg of ultra pure NaI(Tl) crystals will be used as target, divided into 20 modules, 12.5 kg mass each, and coupled to two high efficiency photomultiplier tubes from Hamamatsu. The ANAIS-25 set-up at the LSC consists of two prototypes, amounting 25 kg NaI(Tl), grown from a powder having a potassium level under the limit of our analytical techniques, and installed in a convenient shielding at the LSC. The background has been carefully analyzed and main results will be summarized in this paper, focusing on the alpha contamination identified in the prototypes and the related background contributions. Status of fulfillment of ANAIS experimental goals and prospects for the building of ANAIS-250 experiment will be also revised.

  12. Separation of transuranium elements from irradiated targets

    SciTech Connect

    Wham, R.M.; Benker, D.E.; Felker, L.K.; Chattin, F.R.

    1993-12-31

    Aluminum targets containing curium/americium oxide are irradiated to produce the transcurium actinides einsteinium, fermium, berkelium, and californium. Recovery of recycle curium/americium and the transcurium elements involves several chemical processing steps to selectively recover those elements and remove fission products. Chemical processing steps developed at the Radiochemical Engineering Development Center (REDC) include aluminum dejacketing, solvent extraction to remove bulk impurities, solvent extraction to remove plutonium, anion exchange to partition curium and transcurium elements from the rare earths, and a second anion exchange cycle to separate americium/curium from the transcurium elements.

  13. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade.

    PubMed

    Kondrashev, S; Dickerson, C; Levand, A; Ostroumov, P N; Pardo, R C; Savard, G; Vondrasek, R; Alessi, J; Beebe, E; Pikin, A; Kuznetsov, G I; Batazova, M A

    2012-02-01

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs(+) surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved ∼70% injection∕extraction efficiency and breeding efficiency into the most abundant charge state of ∼17%.

  14. Neutron flux characterization of californium-252 Neutron Research Facility at the University of Texas - Pan American by nuclear analytical technique

    NASA Astrophysics Data System (ADS)

    Wahid, Kareem; Sanchez, Patrick; Hannan, Mohammad

    2014-03-01

    In the field of nuclear science, neutron flux is an intrinsic property of nuclear reaction facilities that is the basis for experimental irradiation calculations and analysis. In the Rio Grande Valley (Texas), the UTPA Neutron Research Facility (NRF) is currently the only neutron facility available for experimental research purposes. The facility is comprised of a 20-microgram californium-252 neutron source surrounded by a shielding cascade containing different irradiation cavities. Thermal and fast neutron flux values for the UTPA NRF have yet to be fully investigated and may be of particular interest to biomedical studies in low neutron dose applications. Though a variety of techniques exist for the characterization of neutron flux, neutron activation analysis (NAA) of metal and nonmetal foils is a commonly utilized experimental method because of its detection sensitivity and availability. The aim of our current investigation is to employ foil activation in the determination of neutron flux values for the UTPA NSRF for further research purposes. Neutron spectrum unfolding of the acquired experimental data via specialized software and subsequent comparison for consistency with computational models lends confidence to the results.

  15. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgradea)

    NASA Astrophysics Data System (ADS)

    Kondrashev, S.; Dickerson, C.; Levand, A.; Ostroumov, P. N.; Pardo, R. C.; Savard, G.; Vondrasek, R.; Alessi, J.; Beebe, E.; Pikin, A.; Kuznetsov, G. I.; Batazova, M. A.

    2012-02-01

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs+ surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved ˜70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of ˜17%.

  16. Operational experience with the Argonne National Laboratory Californium Rare Ion Breeder Upgrade facility and electron cyclotron resonance charge breeder

    NASA Astrophysics Data System (ADS)

    Vondrasek, R.; Clark, J.; Levand, A.; Palchan, T.; Pardo, R.; Savard, G.; Scott, R.

    2014-02-01

    The Californium Rare Ion Breeder Upgrade (CARIBU) of the Argonne National Laboratory Argonne Tandem Linac Accelerator System (ATLAS) facility provides low-energy and accelerated neutron-rich radioactive beams to address key nuclear physics and astrophysics questions. A 350 mCi 252Cf source produces fission fragments which are thermalized and collected by a helium gas catcher into a low-energy particle beam with a charge of 1+ or 2+. An electron cyclotron resonance (ECR) ion source functions as a charge breeder in order to raise the ion charge sufficiently for acceleration in the ATLAS linac. The ECR charge breeder has achieved stable beam charge breeding efficiencies of 10.1% for 23Na7+, 17.9% for 39K10+, 15.6% for 84Kr17+, and 12.4% for 133Cs27+. For the radioactive beams, a charge breeding efficiency of 11.7% has been achieved for 143Cs27+ and 14.7% for 143Ba27+. The typical breeding times are 10 ms/charge state, but the source can be tuned such that this value increases to 100 ms/charge state with the best breeding efficiency corresponding to the longest breeding times—the variation of efficiencies with breeding time will be discussed. Efforts have been made to characterize and reduce the background contaminants present in the ion beam through judicious choice of q/m combinations. Methods of background reduction are being investigated based upon plasma chamber cleaning and vacuum practices.

  17. Operational experience with the Argonne National Laboratory Californium Rare Ion Breeder Upgrade facility and electron cyclotron resonance charge breeder.

    PubMed

    Vondrasek, R; Clark, J; Levand, A; Palchan, T; Pardo, R; Savard, G; Scott, R

    2014-02-01

    The Californium Rare Ion Breeder Upgrade (CARIBU) of the Argonne National Laboratory Argonne Tandem Linac Accelerator System (ATLAS) facility provides low-energy and accelerated neutron-rich radioactive beams to address key nuclear physics and astrophysics questions. A 350 mCi (252)Cf source produces fission fragments which are thermalized and collected by a helium gas catcher into a low-energy particle beam with a charge of 1+ or 2+. An electron cyclotron resonance (ECR) ion source functions as a charge breeder in order to raise the ion charge sufficiently for acceleration in the ATLAS linac. The ECR charge breeder has achieved stable beam charge breeding efficiencies of 10.1% for (23)Na(7+), 17.9% for (39)K(10+), 15.6% for (84)Kr(17+), and 12.4% for (133)Cs(27+). For the radioactive beams, a charge breeding efficiency of 11.7% has been achieved for (143)Cs(27+) and 14.7% for (143)Ba(27+). The typical breeding times are 10 ms/charge state, but the source can be tuned such that this value increases to 100 ms/charge state with the best breeding efficiency corresponding to the longest breeding times-the variation of efficiencies with breeding time will be discussed. Efforts have been made to characterize and reduce the background contaminants present in the ion beam through judicious choice of q/m combinations. Methods of background reduction are being investigated based upon plasma chamber cleaning and vacuum practices.

  18. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    SciTech Connect

    Kondrashev S.; Alessi J.; Dickerson, C.; Levand, A.; Ostroumov, P.N.; Pardo, R.C.; Savard, G.; Vondrasek, R.; Beebe, E.; Pikin, A.; Kuznetsov, G.I.; Batazova, M.A.

    2012-02-03

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  19. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    SciTech Connect

    Kondrashev, S.; Dickerson, C.; Levand, A.; Ostroumov, P. N.; Pardo, R. C.; Savard, G.; Vondrasek, R.; Alessi, J.; Beebe, E.; Pikin, A.; Kuznetsov, G. I.; Batazova, M. A.

    2012-02-15

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  20. Early-stage esophageal squamous cell carcinoma treated with californium-252 neutron brachytherapy: clinical report on 16 cases.

    PubMed

    Liu, Huiming; Wang, Qifeng; Jia, Xitang; Liu, Bo; Wang, C-K Chris

    2013-01-01

    Californium-252 (²⁵²Cf) neutron brachytherapy is a form of high linear energy transfer radiotherapy, which has proven effective when used in combination with external beam radiotherapy to treat intracavitary cancers of the cervix, colon/rectum and esophagus. No study has been reported for treatment of intracavitary cancers with neutron brachytherapy alone. The aim of the study was to observe and analyze the long-term curative effects and complications for early stage thoracic esophageal cancer patients treated with neutron brachytherapy alone. From December 2001 to August 2006, 16 patients of early stage squamous cell carcinoma underwent neutron brachytherapy. The total radiation dose to the reference point was 20-28 Gy-eq in 5 to 7 fractions with 4 Gy-eq/fraction. The 1-, 3-, and 5-year follow-up rates were 100%. The 2-, 3-, 4-, and 5-year survival rates were 100%, 87.5%, 87.5%, and 75%, respectively. The early complication rates for grades 1 and 2 radiation esophagitis were 75% and 25%, respectively. The late complication rates for grades 0 and 1 (according to the RTOG/EORTC standard) were 87.5% and 12.5%, respectively. Barium esophagography after treatments confirmed that the complete response rate was 100%. Fourteen patients were confirmed by endoscopy to have either normal mucosa or inflammation change. Neutron brachytherapy alone was an effective and safe treatment for early stage esophageal squamous cell cancer.

  1. [Reoxygenation of tumors of the uterine cervix during combined radiotherapy using low dose gamma-neutron irradiation with californium-252].

    PubMed

    Tacev, T; Rasovská, O; Strnad, V; Krystof, V; Prokes, B; Vacek, A

    1989-03-01

    A polarographic method was used to follow the changes in oxygenation of a tumour of uterus cervix after intracavital irradiation by 252Cf by a physical dose of 2 Gy, applied at the beginning of a therapeutic cycle of combined radiotherapy. The results reached are compared with the results of tumour oxygenation in the course of a conventional therapeutic procedure. It has become apparent that even after the irradiation of a tumour of uterus cervix by a small dose of gamma-neutron radiation with 252Cf there is, beginning with 2nd week of therapy, a significant reoxygenation of the tumour population. The changes of oxygenation after a conventional irradiation have been less marked and reached, in the 4th week of therapy, only marginally significant increase. Differences in reoxygenation of tumours of uterus cervix were confirmed by analysis of the oxygen test. The importance of tumour reoxygenation after the application of 252Cf source of radiation for facilitation of its regression in a combined treatment with Californium-252 and gamma irradiation is discussed.

  2. Treatment of stage IIIB cervical cancer with Californium-252 fast-neutron brachytherapy and external photon therapy

    SciTech Connect

    Gallion, H.H.; Maruyama, Y.; van Nagell, J.R. Jr.; Donaldson, E.S.; Rowley, K.C.; Yoneda, J.; Beach, J.L.; Powell, D.E.; Kryscio, R.J.

    1987-05-15

    From January 1977 to July 1984, 32 patients with Stage IIIB cervical cancer were treated at the University of Kentucky Medical Center by a combination of outpatient neutron brachytherapy and external pelvic radiation. These patients received 4500 to 5000 rad external photon therapy and two or three outpatient Californium-252 (252Cf) implants, plus sidewall boost irradiation. Treatment results were compared retrospectively to those obtained in a historical control group of patients with Stage IIIB cervical cancer treated with external radiation and conventional photon brachytherapy from 1972 to 1976. Local or regional tumor recurrence developed in 53% of patients treated with neutron therapy and an additional 9% experienced distant metastases. Thirty-eight percent of patients remain free of disease 12 to 96 months (mean, 51 months) after therapy. The 2-year and 5-year survival rates of patients treated with neutron therapy were 53% and 36%, which were not significantly different than those obtained with photon brachytherapy (2-year survival, 61%; 5-year survival, 34%). Complications of neutron therapy were minimal and included proctitis (19%) and vaginal stenosis (9%). There were no cases of enteric fistulae. Outpatient neutron brachytherapy was cost effective and was well tolerated by patients.

  3. Treatment of stage IIIB cervical cancer with Californium-252 fast-neutron brachytherapy and external photon therapy.

    PubMed

    Gallion, H H; Maruyama, Y; van Nagell, J R; Donaldson, E S; Rowley, K C; Yoneda, J; Beach, J L; Powell, D E; Kryscio, R J

    1987-05-15

    From January 1977 to July 1984, 32 patients with Stage IIIB cervical cancer were treated at the University of Kentucky Medical Center by a combination of outpatient neutron brachytherapy and external pelvic radiation. These patients received 4500 to 5000 rad external photon therapy and two or three outpatient Californium-252 (252Cf) implants, plus sidewall boost irradiation. Treatment results were compared retrospectively to those obtained in a historical control group of patients with Stage IIIB cervical cancer treated with external radiation and conventional photon brachytherapy from 1972 to 1976. Local or regional tumor recurrence developed in 53% of patients treated with neutron therapy and an additional 9% experienced distant metastases. Thirty-eight percent of patients remain free of disease 12 to 96 months (mean, 51 months) after therapy. The 2-year and 5-year survival rates of patients treated with neutron therapy were 53% and 36%, which were not significantly different than those obtained with photon brachytherapy (2-year survival, 61%; 5-year survival, 34%). Complications of neutron therapy were minimal and included proctitis (19%) and vaginal stenosis (9%). There were no cases of enteric fistulae. Outpatient neutron brachytherapy was cost effective and was well tolerated by patients.

  4. LOW THERMAL LIMIT OF GROWTH RATE OF SYMBIODINIUM CALIFORNIUM (DINOPHYTA) IN CULTURE MAY RESTRICT THE SYMBIONT TO SOUTHERN POPULATIONS OF ITS HOST ANEMONES (ANTHOPLEURA SPP.; ANTHOZOA, CNIDARIA)(1).

    PubMed

    McBride, Brooke Baldauf; Muller-Parker, Gisèle; Jakobsen, Hans Henrik

    2009-08-01

    Symbiodinium californium (#383, Banaszak et al. 1993) is one of two known dinoflagellate symbionts of the intertidal sea anemones Anthopleura elegantissima, A. xanthogrammica, and A. sola and occurs only in hosts at southern latitudes of the North Pacific. To investigate if temperature restricts the latitudinal distribution of S. californium, growth and photosynthesis at a range of temperatures (5°C-30°C) were determined for cultured symbionts. Mean specific growth rates were the highest between 15°C and 28°C (μ 0.21-0.26 · d(-1) ) and extremely low at 5, 10, and 30°C (0.02-0.03 · d(-1) ). Average doubling times ranged from 2.7 d (20°C) to 33 d (5, 10, and 30°C). Cells cultured at 10°C had the greatest cell volume (821 μm(3) ) and the highest percentage of motile cells (64.5%). Growth and photosynthesis were uncoupled; light-saturated maximum photosynthesis (Pmax ) increased from 2.9 pg C · cell(-1 ) · h(-1) at 20°C to 13.2 pg C · cell(-1 ) · h(-1) at 30°C, a 4.5-fold increase. Less than 11% of daily photosynthetically fixed carbon was utilized for growth at 5, 10, and 30°C, indicating the potential for high carbon translocation at these temperatures. Low temperature effects on growth rate, and not on photosynthesis and cell morphology, may restrict the distribution of S. californium to southern populations of its host anemones.

  5. 30 CFR 250.1627 - Production requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Production requirements. 250.1627 Section 250... Operations § 250.1627 Production requirements. (a) The lessee shall conduct sulphur production operations in compliance with the approved Development and Production Plan requirements of §§ 250.1627 through 250.1634...

  6. Results with the electron cyclotron resonance charge breeder for the 252Cf fission source project (Californium Rare Ion Breeder Upgrade) at Argonne Tandem Linac Accelerator System.

    PubMed

    Vondrasek, R; Kondrashev, S; Pardo, R; Scott, R; Zinkann, G P

    2010-02-01

    The construction of the Californium Rare Ion Breeder Upgrade, a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS), is nearing completion. The facility will use fission fragments from a 1 Ci (252)Cf source; thermalized and collected into a low-energy particle beam by a helium gas catcher. In order to reaccelerate these beams, an existing ATLAS electron cyclotron resonance (ECR) ion source was redesigned to function as an ECR charge breeder. Thus far, the charge breeder has been tested with stable beams of rubidium and cesium achieving charge breeding efficiencies of 9.7% into (85)Rb(17+) and 2.9% into (133)Cs(20+).

  7. 14 CFR 250.7 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false 250.7 Section 250.7 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS OVERSALES § 250.7 ...

  8. 48 CFR 250.104 - Residual powers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Residual powers. 250.104 Section 250.104 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractual Actions 250.104 Residual powers....

  9. 48 CFR 250.104 - Residual powers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Residual powers. 250.104 Section 250.104 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractual Actions 250.104 Residual powers....

  10. 48 CFR 250.104 - Residual powers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Residual powers. 250.104 Section 250.104 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractual Actions 250.104 Residual powers....

  11. 48 CFR 250.104 - Residual powers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Residual powers. 250.104 Section 250.104 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractual Actions 250.104 Residual powers....

  12. 48 CFR 250.104 - Residual powers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Residual powers. 250.104 Section 250.104 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Contractual Actions 250.104 Residual powers....

  13. Early changes in flow cytometric DNA profiles induced by californium-252 neutron brachytherapy in squamocellular carcinomas of the uterine cervix.

    PubMed

    Tacev, T; Zaloudík, J; Janáková, L; Vagunda, V

    1998-01-01

    Ninety-five squamocellular carcinomas of the uterine cervix, clinical Stages II and III, were treated by either four schedules combining 252-californium neutron-gamma-radiotherapy with different proportions of a neutron component (9, 6 and 3 Gy) or gamma-irradiation alone. Flow cytometric DNA profiles were obtainable in 72 cases before treatment and 56 cases were monitored for DNA content by flow cytometry (FCM) in weekly intervals by analysis of sequential microbiopsies for one month during and after radiotherapy. DNA aneuploidy was reduced from 40% (25/63) to 19% (9/47) one week within therapy in neutron-treated groups, but not after initial gamma-radiotherapy alone. Extinction of DNA aneuploid subpopulations occurred after neutron therapy in all remaining aneuploid tumors (9/9) during further monitoring, but only in 40% (2/5) of tumors after sole gamma-irradiation. In contrast, proliferation index by more than 50% was more often achieved in groups with a higher gamma-radiation component than after neutrons only. When all therapy-induced DNA flow cytometric events are taken together for evaluation of the effects of various radiotherapy schedules, it appears that the regimen with the maximal neutron dose may not be optimal for all tumors. It is hypothesized that the differences in the early flow cytometric DNA profiles may select the DNA aneuploid squamous cell uterine cervical carcinomas as candidates for combined neutron-brachytherapy, while highly proliferating DNA near-diploid tumors may profit more from treatment with a higher gamma-radiotherapy component. However, these early DNA flow cytometric findings need to be correlated with clinical course of the disease to validate this hypothesis, a process which will be completed at the end of the expected five-year clinical outcome in 2000.

  14. Chemical Treatment of US Department of Energy High Level and Low Level Waste to Obtain a Pure Radiochemical Fraction for Determination of Californium Alpha-Decay Content

    SciTech Connect

    Dewberry, R.

    2002-12-02

    We have developed a chemical separation technique that allows the radiochemical determination of the californium a-decay content in Department of Energy (DOE) high level wastes from the Hanford and Savannah River sites. The chemical separation technique uses a series of column extraction chromatography steps that use Eichrom Industries' lanthanide and actinide plus 3 oxidation state selective Ln-resin(R) and the transuranic selective plus 4 oxidation state TRU-resin(R) to obtain intermediate product phases in dilute nitric acid. The technique has been demonstrated on three types of authentic DOE high and low level waste samples. We obtain discrimination from Pu a-activity by a factor of over 200 and from Cm-244 a-activity by a factor approaching 1700. Californium recoveries are measured by addition of a Cf-249 spike and are in the range of 50 percent to 90 percent in the synthetic samples and are in the range of 1.4 percent to 48 percent for the authentic DOE waste samples.

  15. Ab initio full-potential study of mechanical properties and magnetic phase stability of californium monopnictides (CfN and CfP)

    NASA Astrophysics Data System (ADS)

    Amari, S.; Bouhafs, B.

    2016-09-01

    Based on the first-principles methods, the structural, elastic, electronic, properties and magnetic ordering of californium monopnictides CfX (X = P) have been studied using the full-potential augmented plane wave plus local orbitals (FP-L/APW + lo) method within the framework of density functional theory (DFT). The electronic exchange correlation energy is described by generalized gradient approximation GGA and GGA+U (U is the Hubbard correction). The GGA+U method is applied to the rare-earth 5f states. We have calculated the lattice parameters, bulk modulii and the first pressure derivatives of the bulk modulii. The elastic properties of the studied compounds are only investigated in the most stable calculated phase. In order to gain further information, we have calculated Young's modulus, shear modulus, anisotropy factor and Kleinman parameter by the aid of the calculated elastic constants. The results mainly show that californium monopnictides CfX (X = P) have an antiferromagnetic spin ordering. Density of states (DOS) and charge densities for both compounds are also computed in the NaCl (B1) structure.

  16. Use of polyethylene pellets in the design and construction of a storage safe, a transport vessel and a portable shield for californium-252

    SciTech Connect

    Sharma, S.

    1986-01-01

    A storage and shielding facility for 300 ..mu..g of Californium-252 sources was designed and constructed. Though the safe was in a permanent location, the fact that it consisted of a lead bucket surrounded by polyethylene pellets made it simple, movable and inexpensive. If need be, more quantities of Cf-252 could be added without altering the basic design and sacrificing the radiation protection guidelines. The measured radiation levels from 300 ..mu..g of stored Cf-252 in and around the storage vault were lower than the expected dose rates by a factor of 5. The measured radiation levels around the occupied environs of the facility were below the maximum permissible yearly dose of 500mrem for non-occupational workers. A transport vessel was designed and constructed to carry up to 50 ..mu..g of Californium-252 sources. It consisted of a standard 55 gallon steel drum on casters containing cylindrical lead shield surrounded by polyethylene pellets. The measured maximum surface dose rates on the drum and at one meter away were within the radiation protection guidelines and were less than the expected dose rates. A portable shield was designed and constructed to protect the body in afterloading operations and handling of the sources. It consisted of polyethylene pellets in an aluminum box and an attached 10 cm thick plexiglass eye shield. The simple design, with the ease of using polyethylene pellets can be extended to construct bedside shields.

  17. 48 CFR 250.101-3 - Records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Records. 250.101-3 Section 250.101-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF... Actions 250.101-3 Records. Follow the procedures at PGI 250.101-3 for preparation of records. ...

  18. 48 CFR 250.101-3 - Records.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Records. 250.101-3 Section 250.101-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF... Actions 250.101-3 Records. Follow the procedures at PGI 250.101-3 for preparation of records. ...

  19. 30 CFR 250.1401 - Index table.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf (OCS) Civil Penalties § 250.1401 Index table. The following table is an index of the sections in this subpart: § 250.1401Table Definitions... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Index table. 250.1401 Section 250.1401 Mineral...

  20. 30 CFR 250.1401 - Index table.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... an index of the sections in this subpart: § 250.1401Table Definitions § 250.1402 What is the maximum... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Index table. 250.1401 Section 250.1401 Mineral... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Civil...

  1. 48 CFR 250.101-3 - Records.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Records. 250.101-3 Section 250.101-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF... Actions 250.101-3 Records. Follow the procedures at PGI 250.101-3 for preparation of records....

  2. 30 CFR 250.808 - Hydrogen sulfide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Hydrogen sulfide. 250.808 Section 250.808... Safety Systems § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in zones where the presence of H2S is unknown, as defined in § 250.490 of this...

  3. 30 CFR 250.1605 - Drilling requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Drilling requirements. 250.1605 Section 250... SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1605 Drilling requirements. (a) Lessees of OCS sulphur leases shall conduct drilling operations in accordance with §§ 250.1605 through...

  4. Low-Dose-Rate Californium-252 Neutron Intracavitary Afterloading Radiotherapy Combined With Conformal Radiotherapy for Treatment of Cervical Cancer

    SciTech Connect

    Zhang Min; Xu Hongde; Pan Songdan; Lin Shan; Yue Jianhua; Liu Jianren

    2012-07-01

    Purpose: To study the efficacy of low-dose-rate californium-252 ({sup 252}Cf) neutron intracavitary afterloading radiotherapy (RT) combined with external pelvic RT for treatment of cervical cancer. Methods and Materials: The records of 96 patients treated for cervical cancer from 2006 to 2010 were retrospectively reviewed. For patients with tumors {<=}4 cm in diameter, external beam radiation was performed (1.8 Gy/day, five times/week) until the dose reached 20 Gy, and then {sup 252}Cf neutron intracavitary afterloading RT (once/week) was begun, and the frequency of external beam radiation was changed to four times/week. For patients with tumors >4 cm, {sup 252}Cf RT was performed one to two times before whole-pelvis external beam radiation. The tumor-eliminating dose was determined by using the depth limit of 5 mm below the mucosa as the reference point. In all patients, the total dose of the external beam radiation ranged from 46.8 to 50 Gy. For {sup 252}Cf RT, the dose delivered to point A was 6 Gy/fraction, once per week, for a total of seven times, and the total dose was 42 Gy. Results: The mean {+-} SD patient age was 54.7 {+-} 13.7 years. Six patients had disease assessed at stage IB, 13 patients had stage IIA, 49 patients had stage IIB, 3 patients had stage IIIA, 24 patients had stage IIIB, and 1 patient had stage IVA. All patients obtained complete tumor regression (CR). The mean {+-} SD time to CR was 23.5 {+-} 3.4 days. Vaginal bleeding was fully controlled in 80 patients within 1 to 8 days. The mean {+-} SD follow-up period was 27.6 {+-} 12.7 months (range, 6-48 months). Five patients died due to recurrence or metastasis. The 3-year survival and disease-free recurrence rates were 89.6% and 87.5 %, respectively. Nine patients experienced mild radiation proctitis, and 4 patients developed radiocystitis. Conclusions: Low-dose-rate {sup 252}Cf neutron RT combined with external pelvic RT is effective for treating cervical cancer, with a low incidence of

  5. Low-dose-rate californium-252 neutron intracavitary afterloading radiotherapy combined with conformal radiotherapy for treatment of cervical cancer.

    PubMed

    Zhang, Min; Xu, Hong-De; Pan, Song-Dan; Lin, Shan; Yue, Jian-Hua; Liu, Jian-Ren

    2012-07-01

    To study the efficacy of low-dose-rate californium-252 ((252)Cf) neutron intracavitary afterloading radiotherapy (RT) combined with external pelvic RT for treatment of cervical cancer. The records of 96 patients treated for cervical cancer from 2006 to 2010 were retrospectively reviewed. For patients with tumors ≤4 cm in diameter, external beam radiation was performed (1.8 Gy/day, five times/week) until the dose reached 20 Gy, and then (252)Cf neutron intracavitary afterloading RT (once/week) was begun, and the frequency of external beam radiation was changed to four times/week. For patients with tumors >4 cm, (252)Cf RT was performed one to two times before whole-pelvis external beam radiation. The tumor-eliminating dose was determined by using the depth limit of 5 mm below the mucosa as the reference point. In all patients, the total dose of the external beam radiation ranged from 46.8 to 50 Gy. For (252)Cf RT, the dose delivered to point A was 6 Gy/fraction, once per week, for a total of seven times, and the total dose was 42 Gy. The mean ± SD patient age was 54.7 ± 13.7 years. Six patients had disease assessed at stage IB, 13 patients had stage IIA, 49 patients had stage IIB, 3 patients had stage IIIA, 24 patients had stage IIIB, and 1 patient had stage IVA. All patients obtained complete tumor regression (CR). The mean ± SD time to CR was 23.5 ± 3.4 days. Vaginal bleeding was fully controlled in 80 patients within 1 to 8 days. The mean ± SD follow-up period was 27.6 ± 12.7 months (range, 6-48 months). Five patients died due to recurrence or metastasis. The 3-year survival and disease-free recurrence rates were 89.6% and 87.5 %, respectively. Nine patients experienced mild radiation proctitis, and 4 patients developed radiocystitis. Low-dose-rate (252)Cf neutron RT combined with external pelvic RT is effective for treating cervical cancer, with a low incidence of complications. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. 48 CFR 1846.673 - Distribution of DD Forms 250 and 250c.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Distribution of DD Forms... Reports 1846.673 Distribution of DD Forms 250 and 250c. (a) DD Forms 250 and 250c shall be distributed in accordance with installation procedures. (b) The contractor is responsible for distributing DD Forms 250...

  7. Results with the electron cyclotron resonance charge breeder for the 252Cf fission source project (Californium Rare Ion Breeder Upgrade) at Argonne Tandem Linac Accelerator System

    NASA Astrophysics Data System (ADS)

    Vondrasek, R.; Kondrashev, S.; Pardo, R.; Scott, R.; Zinkann, G. P.

    2010-02-01

    The construction of the Californium Rare Ion Breeder Upgrade, a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS), is nearing completion. The facility will use fission fragments from a 1 Ci C252f source; thermalized and collected into a low-energy particle beam by a helium gas catcher. In order to reaccelerate these beams, an existing ATLAS electron cyclotron resonance (ECR) ion source was redesigned to function as an ECR charge breeder. Thus far, the charge breeder has been tested with stable beams of rubidium and cesium achieving charge breeding efficiencies of 9.7% into R85b17+ and 2.9% into C133s20+.

  8. Results with the electron cyclotron resonance charge breeder for the {sup 252}Cf fission source project (Californium Rare Ion Breeder Upgrade) at Argonne Tandem Linac Accelerator System

    SciTech Connect

    Vondrasek, R.; Kondrashev, S.; Pardo, R.; Scott, R.; Zinkann, G. P.

    2010-02-15

    The construction of the Californium Rare Ion Breeder Upgrade, a new radioactive beam facility for the Argonne Tandem Linac Accelerator System (ATLAS), is nearing completion. The facility will use fission fragments from a 1 Ci {sup 252}Cf source; thermalized and collected into a low-energy particle beam by a helium gas catcher. In order to reaccelerate these beams, an existing ATLAS electron cyclotron resonance (ECR) ion source was redesigned to function as an ECR charge breeder. Thus far, the charge breeder has been tested with stable beams of rubidium and cesium achieving charge breeding efficiencies of 9.7% into {sup 85}Rb{sup 17+} and 2.9% into {sup 133}Cs{sup 20+}.

  9. 30 CFR 250.300 - Pollution prevention.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Pollution prevention. 250.300 Section 250.300... INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pollution Prevention and Control § 250.300 Pollution prevention. (a) During the exploration, development, production, and...

  10. 7 CFR 250.18 - Audits.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Audits. 250.18 Section 250.18 Agriculture Regulations... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.18 Audits. (a) Right of inspection and audit. The Secretary, the Comptroller General of the United States, or any of...

  11. 30 CFR 1217.250 - Audits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Audits. 1217.250 Section 1217.250 Mineral... Revenue AUDITS AND INSPECTIONS Other Solid Minerals § 1217.250 Audits. An audit of the lessee's accounts... duplicate copies of such annual or other audits to the mining supervisor, within 30 days after the...

  12. 21 CFR 1271.250 - Labeling controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Labeling controls. 1271.250 Section 1271.250 Food..., AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.250 Labeling controls. (a) General. You must establish and maintain procedures to control the labeling of HCT/Ps. You must...

  13. 45 CFR 2541.250 - Program income.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... Program income shall be deducted from outlays which may be both Federal and non-Federal as described in... 45 Public Welfare 4 2013-10-01 2013-10-01 false Program income. 2541.250 Section 2541.250 Public... Post-Award Requirements § 2541.250 Program income. (a) General. Grantees are encouraged to earn income...

  14. 30 CFR 250.505 - Subsea completions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Subsea completions. 250.505 Section 250.505... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.505 Subsea completions. No subsea well completion shall be commenced until the lessee obtains written approval from...

  15. 30 CFR 250.605 - Subsea workovers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Subsea workovers. 250.605 Section 250.605... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.605 Subsea workovers. No subsea well-workover operation including routine operations shall be commenced until the lessee...

  16. 2 CFR 1401.250 - Grant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Grant. 1401.250 Section 1401.250 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF THE INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.250 Grant. Grant means an award of...

  17. 2 CFR 1401.250 - Grant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Grant. 1401.250 Section 1401.250 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF THE INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.250 Grant. Grant means an award of...

  18. 2 CFR 1401.250 - Grant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Grant. 1401.250 Section 1401.250 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF THE INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1401.250 Grant. Grant means an award of...

  19. 2 CFR 1401.250 - Grant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Grant. 1401.250 Section 1401.250 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF THE INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) (Eff. 1-21-2011) Definitions § 1401.250 Grant. Grant means...

  20. 8 CFR 250.1 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Application. 250.1 Section 250.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.1 Application. Application for removal shall be made on Form I-243. No appeal shall lie...

  1. 8 CFR 250.2 - Removal authorization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Removal authorization. 250.2 Section 250.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.2 Removal authorization. If the district director grants the application...

  2. 30 CFR 250.1401 - Index table.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Index table. 250.1401 Section 250.1401 Mineral... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Civil Penalties Outer Continental Shelf Lands Act Civil Penalties § 250.1401 Index table. The following table is an index of the...

  3. 30 CFR 250.1401 - Index table.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Index table. 250.1401 Section 250.1401 Mineral... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Civil Penalties Outer Continental Shelf Lands Act Civil Penalties § 250.1401 Index table. The following table is an index of the...

  4. 30 CFR 250.1401 - Index table.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Index table. 250.1401 Section 250.1401 Mineral... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Civil Penalties Outer Continental Shelf Lands Act Civil Penalties § 250.1401 Index table. The following table is an index of the...

  5. 32 CFR 250.4 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 250.4 Section 250.4 National Defense... UNCLASSIFIED TECHNICAL DATA FROM PUBLIC DISCLOSURE § 250.4 Policy. (a) In accordance with 10 U.S.C. 140c, the... governments. (c) Nothwithstanding the authority provided in paragraph (a), of this section, it is DoD policy...

  6. 7 CFR 250.2 - Administration.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 250.2 Section 250.2 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General § 250.2 Administration. (a) Delegation to FNS. Within the Department, FNS shall act on behalf of the Department in the administration of the...

  7. 30 CFR 250.1607 - Field rules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Field rules. 250.1607 Section 250.1607 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1607 Field rules. When geological and...

  8. 30 CFR 250.1607 - Field rules.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Field rules. 250.1607 Section 250.1607 Mineral... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1607 Field rules. When geological and engineering information in a field enables a District Manager to...

  9. 30 CFR 250.1607 - Field rules.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Field rules. 250.1607 Section 250.1607 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1607 Field rules. When...

  10. 30 CFR 250.1607 - Field rules.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Field rules. 250.1607 Section 250.1607 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1607 Field rules. When...

  11. 30 CFR 250.1607 - Field rules.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Field rules. 250.1607 Section 250.1607 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1607 Field rules. When...

  12. 45 CFR 2541.250 - Program income.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Program income. 2541.250 Section 2541.250 Public... Post-Award Requirements § 2541.250 Program income. (a) General. Grantees are encouraged to earn income to defray program costs. Program income includes income from fees for services performed, from the...

  13. 7 CFR 250.23 - Buy American.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Buy American. 250.23 Section 250.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.23 Buy...

  14. 7 CFR 250.23 - Buy American.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Buy American. 250.23 Section 250.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.23 Buy...

  15. 7 CFR 250.23 - Buy American.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Buy American. 250.23 Section 250.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.23 Buy...

  16. 7 CFR 250.23 - Buy American.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Buy American. 250.23 Section 250.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.23 Buy...

  17. 7 CFR 250.23 - Buy American.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Buy American. 250.23 Section 250.23 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.23 Buy...

  18. 21 CFR 73.250 - Fruit juice.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Fruit juice. 73.250 Section 73.250 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.250 Fruit juice. (a) Identity. (1) The color additive fruit juice is prepared either by expressing the juice from mature varieties of fresh, edible fruits, or by...

  19. 21 CFR 73.250 - Fruit juice.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Fruit juice. 73.250 Section 73.250 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.250 Fruit juice. (a) Identity. (1) The color additive fruit juice is prepared either by expressing the juice from mature varieties of fresh, edible fruits, or by...

  20. 21 CFR 73.250 - Fruit juice.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Fruit juice. 73.250 Section 73.250 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.250 Fruit juice. (a) Identity. (1) The color additive fruit juice is prepared either by expressing the juice from mature varieties of fresh, edible fruits, or by...

  1. 21 CFR 73.250 - Fruit juice.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Fruit juice. 73.250 Section 73.250 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.250 Fruit juice. (a) Identity. (1) The color additive fruit juice is prepared either by expressing the juice from mature varieties of fresh, edible fruits, or by...

  2. 21 CFR 73.250 - Fruit juice.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Fruit juice. 73.250 Section 73.250 Food and Drugs... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.250 Fruit juice. (a) Identity. (1) The color additive fruit juice is prepared either by expressing the juice from mature varieties of fresh, edible fruits, or by...

  3. 20 CFR 627.250 - Interstate agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Interstate agreements. 627.250 Section 627.250 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR GENERAL PROVISIONS GOVERNING PROGRAMS UNDER TITLES I, II, AND III OF THE ACT Program Requirements § 627.250 Interstate...

  4. 20 CFR 627.250 - Interstate agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Interstate agreements. 627.250 Section 627.250 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR GENERAL PROVISIONS GOVERNING PROGRAMS UNDER TITLES I, II, AND III OF THE ACT Program Requirements § 627.250 Interstate...

  5. 30 CFR 250.1203 - Gas measurement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Gas measurement. 250.1203 Section 250.1203... INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Measurement, Surface Commingling, and Security § 250.1203 Gas measurement. (a) To which meters do MMS...

  6. 41 CFR 60-250.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OFFICE OF FEDERAL CONTRACT COMPLIANCE PROGRAMS, EQUAL EMPLOYMENT OPPORTUNITY, DEPARTMENT OF LABOR 250... Preliminary Matters, Equal Opportunity Clause § 60-250.2 Definitions. For the purpose of this part: (a) Act...). (b) Equal opportunity clause means the contract provisions set forth in § 60-250.5, “Equal...

  7. 30 CFR 250.600 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false General requirements. 250.600 Section 250.600 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.600 General requirements...

  8. 30 CFR 250.500 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false General requirements. 250.500 Section 250.500 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.500 General...

  9. 30 CFR 250.501 - Definition.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definition. 250.501 Section 250.501 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.501 Definition. When...

  10. 30 CFR 250.501 - Definition.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Definition. 250.501 Section 250.501 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.501...

  11. 30 CFR 250.501 - Definition.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Definition. 250.501 Section 250.501 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.501...

  12. 30 CFR 250.501 - Definition.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Definition. 250.501 Section 250.501 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.501...

  13. 30 CFR 250.125 - Service fees.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Service fees. 250.125 Section 250.125 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Fees § 250.125 Service fees. (a)...

  14. 21 CFR 1271.250 - Labeling controls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Labeling controls. 1271.250 Section 1271.250 Food..., AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.250 Labeling controls. (a) General. You must establish and maintain procedures to control the labeling of HCT/Ps. You must design...

  15. 21 CFR 1271.250 - Labeling controls.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Labeling controls. 1271.250 Section 1271.250 Food..., AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.250 Labeling controls. (a) General. You must establish and maintain procedures to control the labeling of HCT/Ps. You must design...

  16. 21 CFR 1271.250 - Labeling controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Labeling controls. 1271.250 Section 1271.250 Food..., AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.250 Labeling controls. (a) General. You must establish and maintain procedures to control the labeling of HCT/Ps. You must design...

  17. 32 CFR 250.6 - Responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 250.6 Section 250.6 National... WITHHOLDING OF UNCLASSIFIED TECHNICAL DATA FROM PUBLIC DISCLOSURE § 250.6 Responsibilities. (a) The Under Secretary of Defense for Research and Engineering (USDR&E) shall have overall responsibility for...

  18. 30 CFR 217.250 - Audits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Audits. 217.250 Section 217.250 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT AUDITS AND INSPECTIONS Other Solid Minerals § 217.250 Audits. An audit of the lessee's accounts and books may be...

  19. 7 CFR 250.18 - Audits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Audits. 250.18 Section 250.18 Agriculture Regulations... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.18 Audits. (a) Right of inspection and audit. The Secretary, the Comptroller General of the United States, or any...

  20. 46 CFR 199.250 - Drills.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Drills. 199.250 Section 199.250 Shipping COAST GUARD... CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.250 Drills. (a) An abandon-ship drill and a fire drill, as described in § 199.180, must be conducted on each passenger vessel at...

  1. 46 CFR 199.250 - Drills.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Drills. 199.250 Section 199.250 Shipping COAST GUARD... CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.250 Drills. (a) An abandon-ship drill and a fire drill, as described in § 199.180, must be conducted on each passenger vessel at...

  2. 46 CFR 199.250 - Drills.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Drills. 199.250 Section 199.250 Shipping COAST GUARD... CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.250 Drills. (a) An abandon-ship drill and a fire drill, as described in § 199.180, must be conducted on each passenger vessel at...

  3. 46 CFR 199.250 - Drills.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Drills. 199.250 Section 199.250 Shipping COAST GUARD... CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.250 Drills. (a) An abandon-ship drill and a fire drill, as described in § 199.180, must be conducted on each passenger vessel at...

  4. 30 CFR 250.504 - Hydrogen sulfide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Hydrogen sulfide. 250.504 Section 250.504 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... § 250.490 of this part), the lessee shall take appropriate precautions to protect life and property...

  5. 30 CFR 250.604 - Hydrogen sulfide.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Hydrogen sulfide. 250.604 Section 250.604 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... § 250.490 of this part), the lessee shall take appropriate precautions to protect life and property...

  6. 21 CFR 820.250 - Statistical techniques.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Statistical techniques. 820.250 Section 820.250...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Statistical Techniques § 820.250 Statistical techniques. (a... statistical techniques required for establishing, controlling, and verifying the acceptability of...

  7. 21 CFR 820.250 - Statistical techniques.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Statistical techniques. 820.250 Section 820.250...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Statistical Techniques § 820.250 Statistical techniques. (a... statistical techniques required for establishing, controlling, and verifying the acceptability of...

  8. 21 CFR 820.250 - Statistical techniques.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Statistical techniques. 820.250 Section 820.250...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Statistical Techniques § 820.250 Statistical techniques. (a... statistical techniques required for establishing, controlling, and verifying the acceptability of...

  9. 21 CFR 820.250 - Statistical techniques.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Statistical techniques. 820.250 Section 820.250...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Statistical Techniques § 820.250 Statistical techniques. (a... statistical techniques required for establishing, controlling, and verifying the acceptability of...

  10. 30 CFR 250.1204 - Surface commingling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Surface commingling. 250.1204 Section 250.1204... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Measurement, Surface Commingling, and Security § 250.1204 Surface commingling. (a) What are the requirements for the surface commingling...

  11. 30 CFR 250.1627 - Production requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Production requirements. 250.1627 Section 250... SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1627 Production requirements. (a) The lessee shall conduct sulphur production operations in compliance with the...

  12. 30 CFR 250.1632 - Production rates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Production rates. 250.1632 Section 250.1632 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... § 250.1632 Production rates. Each sulphur deposit shall be produced at rates that will provide...

  13. 30 CFR 250.1632 - Production rates.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Production rates. 250.1632 Section 250.1632 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1632 Production rates. Each...

  14. 30 CFR 250.1633 - Production measurement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Production measurement. 250.1633 Section 250... Operations § 250.1633 Production measurement. (a) General. Measurement equipment and security procedures.... The lessee shall not commence production of sulphur until the Regional Supervisor has approved...

  15. 30 CFR 250.1633 - Production measurement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Production measurement. 250.1633 Section 250... SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1633 Production measurement. (a... determination. (b) Application and approval. The lessee shall not commence production of sulphur until...

  16. 40 CFR 723.250 - Polymers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Polymers. 723.250 Section 723.250... PREMANUFACTURE NOTIFICATION EXEMPTIONS Specific Exemptions § 723.250 Polymers. (a) Purpose and scope. (1) This...) of the Toxic Substances Control Act (15 U.S.C. 2604(a)(1)(A)) for the manufacture of certain...

  17. 40 CFR 723.250 - Polymers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Polymers. 723.250 Section 723.250... PREMANUFACTURE NOTIFICATION EXEMPTIONS Specific Exemptions § 723.250 Polymers. (a) Purpose and scope. (1) This...) of the Toxic Substances Control Act (15 U.S.C. 2604(a)(1)(A)) for the manufacture of certain...

  18. 30 CFR 250.504 - Hydrogen sulfide.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.504 Section 250.504... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.504 Hydrogen sulfide. When a well-completion operation is conducted in zones known to contain hydrogen sulfide (H2S) or...

  19. 30 CFR 250.604 - Hydrogen sulfide.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.604 Section 250.604... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.604 Hydrogen sulfide. When a well-workover operation is conducted in zones known to contain hydrogen sulfide (H2S) or...

  20. 30 CFR 250.808 - Hydrogen sulfide.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Hydrogen sulfide. 250.808 Section 250.808... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Safety Systems § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in zones where the presence of...

  1. 21 CFR 820.250 - Statistical techniques.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Statistical techniques. 820.250 Section 820.250 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES QUALITY SYSTEM REGULATION Statistical Techniques § 820.250 Statistical techniques....

  2. 30 CFR 250.808 - Hydrogen sulfide.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Hydrogen sulfide. 250.808 Section 250.808 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in...

  3. 30 CFR 250.808 - Hydrogen sulfide.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Hydrogen sulfide. 250.808 Section 250.808 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in...

  4. 30 CFR 250.808 - Hydrogen sulfide.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Hydrogen sulfide. 250.808 Section 250.808 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... § 250.808 Hydrogen sulfide. Production operations in zones known to contain hydrogen sulfide (H2S) or in...

  5. 7 CFR 250.18 - Audits.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Audits. 250.18 Section 250.18 Agriculture Regulations... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.18 Audits. (a) Right of inspection and audit. The Secretary, the Comptroller General of the United States, or any...

  6. 7 CFR 250.18 - Audits.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Audits. 250.18 Section 250.18 Agriculture Regulations... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.18 Audits. (a) Right of inspection and audit. The Secretary, the Comptroller General of the United States, or any...

  7. 30 CFR 1217.250 - Audits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Audits. 1217.250 Section 1217.250 Mineral Resources OFFICE OF NATURAL RESOURCES REVENUE, DEPARTMENT OF THE INTERIOR NATURAL RESOURCES REVENUE AUDITS AND INSPECTIONS Other Solid Minerals § 1217.250 Audits. An audit of the lessee's accounts and...

  8. 30 CFR 1217.250 - Audits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Audits. 1217.250 Section 1217.250 Mineral Resources OFFICE OF NATURAL RESOURCES REVENUE, DEPARTMENT OF THE INTERIOR NATURAL RESOURCES REVENUE AUDITS AND INSPECTIONS Other Solid Minerals § 1217.250 Audits. An audit of the lessee's accounts and...

  9. 7 CFR 250.18 - Audits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Audits. 250.18 Section 250.18 Agriculture Regulations... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.18 Audits. (a) Right of inspection and audit. The Secretary, the Comptroller General of the United States, or any...

  10. 30 CFR 250.1205 - Site security.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Site security. 250.1205 Section 250.1205... Measurement, Surface Commingling, and Security § 250.1205 Site security. (a) What are the requirements for site security? You must: (1) Protect Federal production against production loss or theft; (2) Post...

  11. 30 CFR 250.1634 - Site security.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Site security. 250.1634 Section 250.1634 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... § 250.1634 Site security. (a) All locations where sulphur is produced, measured, or stored shall...

  12. 48 CFR 250.103-6 - Disposition.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Disposition. 250.103-6... Contractual Actions 250.103-6 Disposition. For requests denied or approved below the Secretarial level, follow the disposition procedures at PGI 250.103-6. ...

  13. 48 CFR 250.103-6 - Disposition.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Disposition. 250.103-6... Contractual Actions 250.103-6 Disposition. For requests denied or approved below the Secretarial level, follow the disposition procedures at PGI 250.103-6. ...

  14. 48 CFR 250.103-6 - Disposition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Disposition. 250.103-6... Contractual Actions 250.103-6 Disposition. For requests denied or approved below the Secretarial level, follow the disposition procedures at PGI 250.103-6. ...

  15. 48 CFR 250.103-6 - Disposition.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Disposition. 250.103-6... Contractual Actions 250.103-6 Disposition. For requests denied or approved below the Secretarial level, follow the disposition procedures at PGI 250.103-6. ...

  16. 48 CFR 250.103-6 - Disposition.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Disposition. 250.103-6... Contractual Actions 250.103-6 Disposition. For requests denied or approved below the Secretarial level, follow the disposition procedures at PGI 250.103-6. ...

  17. 7 CFR 65.250 - Slaughter.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Slaughter. 65.250 Section 65.250 Agriculture... OF BEEF, PORK, LAMB, CHICKEN, GOAT MEAT, PERISHABLE AGRICULTURAL COMMODITIES, MACADAMIA NUTS, PECANS, PEANUTS, AND GINSENG General Provisions Definitions § 65.250 Slaughter. Slaughter means the point in...

  18. 7 CFR 65.250 - Slaughter.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Slaughter. 65.250 Section 65.250 Agriculture... OF BEEF, PORK, LAMB, CHICKEN, GOAT MEAT, PERISHABLE AGRICULTURAL COMMODITIES, MACADAMIA NUTS, PECANS, PEANUTS, AND GINSENG General Provisions Definitions § 65.250 Slaughter. Slaughter means the point in...

  19. 7 CFR 65.250 - Slaughter.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Slaughter. 65.250 Section 65.250 Agriculture... OF BEEF, PORK, LAMB, CHICKEN, GOAT MEAT, PERISHABLE AGRICULTURAL COMMODITIES, MACADAMIA NUTS, PECANS, PEANUTS, AND GINSENG General Provisions Definitions § 65.250 Slaughter. Slaughter means the point in...

  20. 7 CFR 250.21 - Civil rights.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Civil rights. 250.21 Section 250.21 Agriculture... Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil rights... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.21 Civil...

  1. 30 CFR 250.1613 - Diverter systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Diverter systems. 250.1613 Section 250.1613 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1613 Diverter...

  2. 30 CFR 250.1613 - Diverter systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Diverter systems. 250.1613 Section 250.1613 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1613 Diverter systems. (a) When drilling a...

  3. 30 CFR 250.1621 - Crew instructions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Crew instructions. 250.1621 Section 250.1621 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1621 Crew...

  4. 30 CFR 250.1621 - Crew instructions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Crew instructions. 250.1621 Section 250.1621 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1621 Crew...

  5. 30 CFR 250.125 - Service fees.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Service fees. 250.125 Section 250.125 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Fees § 250.125 Service fees. (a) The...

  6. 30 CFR 250.1613 - Diverter systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Diverter systems. 250.1613 Section 250.1613 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1613 Diverter...

  7. 30 CFR 250.1621 - Crew instructions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Crew instructions. 250.1621 Section 250.1621 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1621 Crew...

  8. 30 CFR 250.125 - Service fees.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Service fees. 250.125 Section 250.125 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF General Fees § 250.125 Service fees. (a) The...

  9. 30 CFR 250.1613 - Diverter systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Diverter systems. 250.1613 Section 250.1613 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1613 Diverter...

  10. 30 CFR 250.1923 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false 250.1923 Section 250.1923 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250...

  11. 30 CFR 250.1926 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false 250.1926 Section 250.1926 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250...

  12. 30 CFR 250.1923 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false 250.1923 Section 250.1923 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250...

  13. 30 CFR 250.1926 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false 250.1926 Section 250.1926 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250...

  14. 30 CFR 250.1203 - Gas measurement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Gas measurement. 250.1203 Section 250.1203... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Measurement, Surface Commingling, and Security § 250.1203 Gas measurement. (a) To which meters do MMS requirements for gas measurement apply?...

  15. 8 CFR 250.1 - Application.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Application. 250.1 Section 250.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.1 Application. Application for removal shall be made on Form I-243. No appeal shall lie from...

  16. 8 CFR 250.1 - Application.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Application. 250.1 Section 250.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.1 Application. Application for removal shall be made on Form I-243. No appeal shall lie from...

  17. 8 CFR 250.1 - Application.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Application. 250.1 Section 250.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.1 Application. Application for removal shall be made on Form I-243. No appeal shall lie from...

  18. 8 CFR 250.1 - Application.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Application. 250.1 Section 250.1 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS REMOVAL OF ALIENS WHO HAVE FALLEN INTO DISTRESS § 250.1 Application. Application for removal shall be made on Form I-243. No appeal shall lie from...

  19. 7 CFR 1726.250 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false General. 1726.250 Section 1726.250 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE....250 General. RUS provides standard forms of contract for the procurement of materials, equipment,...

  20. 49 CFR 250.3 - Fees.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Fees. 250.3 Section 250.3 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUARANTEE OF CERTIFICATES OF TRUSTEES OF RAILROADS IN REORGANIZATION § 250.3 Fees. On date...

  1. 32 CFR 250.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Purpose. 250.1 Section 250.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS WITHHOLDING OF UNCLASSIFIED TECHNICAL DATA FROM PUBLIC DISCLOSURE § 250.1 Purpose. This part establishes policy,...

  2. 46 CFR 174.250 - Unrestricted service.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Unrestricted service. 174.250 Section 174.250 Shipping... PERTAINING TO SPECIFIC VESSEL TYPES Special Rules Pertaining to Liftboats § 174.250 Unrestricted service. Each liftboat not limited to restricted service must comply with subpart C of this part in...

  3. 42 CFR 441.250 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Applicability. 441.250 Section 441.250 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Sterilizations § 441.250 Applicability. This subpart applies to sterilizations and hysterectomies...

  4. 49 CFR 250.5 - General instructions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false General instructions. 250.5 Section 250.5..., DEPARTMENT OF TRANSPORTATION GUARANTEE OF CERTIFICATES OF TRUSTEES OF RAILROADS IN REORGANIZATION § 250.5... (49 U.S.C. 20a) in relation to the issuance of Trustee certificates....

  5. 7 CFR 250.21 - Civil rights.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Civil rights. 250.21 Section 250.21 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.21 Civil... Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil...

  6. 7 CFR 250.21 - Civil rights.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Civil rights. 250.21 Section 250.21 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.21 Civil... Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil...

  7. 7 CFR 250.21 - Civil rights.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Civil rights. 250.21 Section 250.21 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.21 Civil... Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil...

  8. 7 CFR 250.21 - Civil rights.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Civil rights. 250.21 Section 250.21 Agriculture... TERRITORIES AND POSSESSIONS AND AREAS UNDER ITS JURISDICTION General Operating Provisions § 250.21 Civil... Department's nondiscrimination regulations (7 CFR parts 15, 15a, and 15b) and the FNS civil...

  9. 5 CFR 250.302 - Survey requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Survey requirements. 250.302 Section 250.302 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Employee Surveys § 250.302 Survey requirements. (a) Each executive agency must conduct...

  10. 5 CFR 250.203 - Agency responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Agency responsibilities. 250.203 Section 250.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in...

  11. 5 CFR 250.102 - Delegated authorities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Delegated authorities. 250.102 Section 250.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.102 Delegated authorities. OPM may...

  12. 5 CFR 250.302 - Survey requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Survey requirements. 250.302 Section 250.302 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Employee Surveys § 250.302 Survey requirements. (a) Each executive agency must conduct...

  13. 5 CFR 250.102 - Delegated authorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Delegated authorities. 250.102 Section 250.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.102 Delegated authorities. OPM may...

  14. 5 CFR 250.102 - Delegated authorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Delegated authorities. 250.102 Section 250.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.102 Delegated authorities. OPM may...

  15. 5 CFR 250.302 - Survey requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Survey requirements. 250.302 Section 250.302 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Employee Surveys § 250.302 Survey requirements. (a) Each executive agency must conduct...

  16. 5 CFR 250.203 - Agency responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Agency responsibilities. 250.203 Section 250.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in...

  17. 5 CFR 250.203 - Agency responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Agency responsibilities. 250.203 Section 250.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in...

  18. 5 CFR 250.203 - Agency responsibilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Agency responsibilities. 250.203 Section 250.203 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in...

  19. 5 CFR 250.102 - Delegated authorities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Delegated authorities. 250.102 Section 250.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.102 Delegated authorities. OPM may...

  20. 30 CFR 250.502 - Equipment movement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Equipment movement. 250.502 Section 250.502... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.502 Equipment movement. The movement of well-completion rigs and related equipment on and off a platform or from well to well...

  1. 30 CFR 250.602 - Equipment movement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Equipment movement. 250.602 Section 250.602... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.602 Equipment movement. The movement of well-workover rigs and related equipment on and off a platform or from well to well on...

  2. 21 CFR 74.250 - Orange B.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Orange B. 74.250 Section 74.250 Food and Drugs... ADDITIVES SUBJECT TO CERTIFICATION Foods § 74.250 Orange B. (a) Identity. (1) The color additive Orange B is.... (2) The diluents in color additive mixtures for food use containing Orange B are limited to those...

  3. 21 CFR 74.250 - Orange B.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Orange B. 74.250 Section 74.250 Food and Drugs... ADDITIVES SUBJECT TO CERTIFICATION Foods § 74.250 Orange B. (a) Identity. (1) The color additive Orange B is.... (2) The diluents in color additive mixtures for food use containing Orange B are limited to those...

  4. 21 CFR 74.250 - Orange B.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Orange B. 74.250 Section 74.250 Food and Drugs... ADDITIVES SUBJECT TO CERTIFICATION Foods § 74.250 Orange B. (a) Identity. (1) The color additive Orange B is.... (2) The diluents in color additive mixtures for food use containing Orange B are limited to those...

  5. 21 CFR 74.250 - Orange B.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Orange B. 74.250 Section 74.250 Food and Drugs... ADDITIVES SUBJECT TO CERTIFICATION Foods § 74.250 Orange B. (a) Identity. (1) The color additive Orange B is.... (2) The diluents in color additive mixtures for food use containing Orange B are limited to those...

  6. 30 CFR 250.601 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions. 250.601 Section 250.601 Mineral... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.601 Definitions. When... restoring the productivity of a well....

  7. 5 CFR 250.102 - Delegated authorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Delegated authorities. 250.102 Section 250.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.102 Delegated authorities. OPM...

  8. 46 CFR 199.250 - Drills.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Drills. 199.250 Section 199.250 Shipping COAST GUARD... CERTAIN INSPECTED VESSELS Additional Requirements for Passenger Vessels § 199.250 Drills. (a) An abandon-ship drill and a fire drill, as described in § 199.180, must be conducted on each passenger vessel...

  9. 30 CFR 250.606 - Crew instructions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Crew instructions. 250.606 Section 250.606... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.606 Crew instructions. Prior to engaging in well-workover operations, crew members shall be instructed in the...

  10. 30 CFR 250.1621 - Crew instructions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Crew instructions. 250.1621 Section 250.1621... OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1621 Crew instructions. Prior to engaging in well-completion or well-workover operations, crew members shall be instructed in the...

  11. 30 CFR 250.506 - Crew instructions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Crew instructions. 250.506 Section 250.506... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.506 Crew instructions. Prior to engaging in well-completion operations, crew members shall be instructed in the...

  12. 30 CFR 250.1619 - Well records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Well records. 250.1619 Section 250.1619 Mineral... OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1619 Well records. (a) Complete and accurate records for each well and all well operations shall be retained for a period of 2 years at...

  13. Calculations of Nuclear Astrophysics and Californium Fission Neutron Spectrum Averaged Cross Section Uncertainties Using ENDF/B-VII.1, JEFF-3.1.2, JENDL-4.0 and Low-fidelity Covariances

    SciTech Connect

    Pritychenko, B.

    2015-01-15

    Nuclear astrophysics and californium fission neutron spectrum averaged cross sections and their uncertainties for ENDF materials have been calculated. Absolute values were deduced with Maxwellian and Mannhart spectra, while uncertainties are based on ENDF/B-VII.1, JEFF-3.1.2, JENDL-4.0 and Low-Fidelity covariances. These quantities are compared with available data, independent benchmarks, EXFOR library, and analyzed for a wide range of cases. Recommendations for neutron cross section covariances are given and implications are discussed.

  14. Calculations of Nuclear Astrophysics and Californium Fission Neutron Spectrum Averaged Cross Section Uncertainties Using ENDF/B-VII.1, JEFF-3.1.2, JENDL-4.0 and Low-fidelity Covariances

    NASA Astrophysics Data System (ADS)

    Pritychenko, B.

    2015-01-01

    Nuclear astrophysics and californium fission neutron spectrum averaged cross sections and their uncertainties for ENDF materials have been calculated. Absolute values were deduced with Maxwellian and Mannhart spectra, while uncertainties are based on ENDF/B-VII.1, JEFF-3.1.2, JENDL-4.0 and Low-Fidelity covariances. These quantities are compared with available data, independent benchmarks, EXFOR library, and analyzed for a wide range of cases. Recommendations for neutron cross section covariances are given and implications are discussed.

  15. 48 CFR 1846.672 - Preparing DD Forms 250 and 250c.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Preparing DD Forms 250 and 250c. 1846.672 Section 1846.672 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... DD Forms 250 and 250c....

  16. 30 CFR 250.1605 - Drilling requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Drilling requirements. 250.1605 Section 250.1605 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF...

  17. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  18. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  19. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  20. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  1. 36 CFR 2.50 - Special events.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Special events. 2.50 Section... PROTECTION, PUBLIC USE AND RECREATION § 2.50 Special events. (a) Sports events, pageants, regattas, public spectator attractions, entertainments, ceremonies, and similar events are allowed: Provided, however,...

  2. 30 CFR 250.200 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Definitions. 250.200 Section 250.200 Mineral....200 Definitions. Acronyms and terms used in this subpart have the following meanings: (a) Acronyms... Plan. DWOP means Deepwater Operations Plan. EIA means Environmental Impact Analysis. EP means...

  3. 30 CFR 250.200 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Definitions. 250.200 Section 250.200 Mineral....200 Definitions. Acronyms and terms used in this subpart have the following meanings: (a) Acronyms... Plan. DWOP means Deepwater Operations Plan. EIA means Environmental Impact Analysis. EP means...

  4. 7 CFR 250.19 - Reviews.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Reviews. 250.19 Section 250.19 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... be written, signed by the proper official in the State, and submitted to the FNSRO within 60...

  5. 30 CFR 250.1619 - Well records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Well records. 250.1619 Section 250.1619 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS... years at the lessee's field office nearest the OCS facility or at another location conveniently...

  6. 30 CFR 250.601 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Definitions. 250.601 Section 250.601 Mineral... Definitions. When used in this subpart, the following terms shall have the meanings given below: Expected... pressure. Routine operations mean any of the following operations conducted on a well with the tree...

  7. 30 CFR 250.505 - Subsea completions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Subsea completions. 250.505 Section 250.505 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations...

  8. 30 CFR 250.505 - Subsea completions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Subsea completions. 250.505 Section 250.505 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations...

  9. 30 CFR 250.500 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false General requirements. 250.500 Section 250.500 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well...

  10. 30 CFR 250.506 - Crew instructions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Crew instructions. 250.506 Section 250.506 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations...

  11. 30 CFR 250.506 - Crew instructions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Crew instructions. 250.506 Section 250.506 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations...

  12. 30 CFR 250.600 - General requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false General requirements. 250.600 Section 250.600 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well...

  13. 30 CFR 250.505 - Subsea completions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Subsea completions. 250.505 Section 250.505 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations...

  14. 30 CFR 250.506 - Crew instructions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Crew instructions. 250.506 Section 250.506 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations...

  15. 21 CFR 1271.250 - Labeling controls.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Labeling controls. 1271.250 Section 1271.250 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION HUMAN CELLS,...

  16. 30 CFR 250.1619 - Well records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Well records. 250.1619 Section 250.1619 Mineral... on cementing, acidizing, analyses of cores, testing, or other similar services. (d) As soon as..., directional-well surveys, and core analyses. Composite logs of multiple runs and directional-well...

  17. 30 CFR 250.1619 - Well records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Well records. 250.1619 Section 250.1619 Mineral... on cementing, acidizing, analyses of cores, testing, or other similar services. (d) As soon as..., directional-well surveys, and core analyses. Composite logs of multiple runs and directional-well...

  18. 7 CFR 250.15 - Financial management.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Financial management. 250.15 Section 250.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... Financial management. (a) Distribution charges. (1) Recipient agencies may be required to pay part or all...

  19. 7 CFR 250.15 - Financial management.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Financial management. 250.15 Section 250.15 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF... Financial management. (a) Distribution charges. (1) Recipient agencies may be required to pay part or all of...

  20. 30 CFR 250.1605 - Drilling requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Drilling requirements. 250.1605 Section 250... Drilling requirements. (a) Sulphur leases. Lessees of OCS sulphur leases shall conduct drilling operations... part, as appropriate. (b) Fitness of drilling unit. (1) Drilling units shall be capable of withstanding...

  1. 30 CFR 250.1605 - Drilling requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Drilling requirements. 250.1605 Section 250... Drilling requirements. (a) Sulphur leases. Lessees of OCS sulphur leases shall conduct drilling operations... part, as appropriate. (b) Fitness of drilling unit. (1) Drilling units shall be capable of withstanding...

  2. 30 CFR 250.1605 - Drilling requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Drilling requirements. 250.1605 Section 250... Drilling requirements. (a) Sulphur leases. Lessees of OCS sulphur leases shall conduct drilling operations... part, as appropriate. (b) Fitness of drilling unit. (1) Drilling units shall be capable of withstanding...

  3. 30 CFR 250.1614 - Mud program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Mud program. 250.1614 Section 250.1614 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS...) The quantities, characteristics, use, and testing of drilling mud and the related drilling...

  4. 30 CFR 250.1614 - Mud program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Mud program. 250.1614 Section 250.1614 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS...) The quantities, characteristics, use, and testing of drilling mud and the related drilling...

  5. 30 CFR 250.1614 - Mud program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Mud program. 250.1614 Section 250.1614 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR..., characteristics, use, and testing of drilling mud and the related drilling procedures shall be designed...

  6. 30 CFR 250.1614 - Mud program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Mud program. 250.1614 Section 250.1614 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS...) The quantities, characteristics, use, and testing of drilling mud and the related drilling...

  7. 30 CFR 250.1600 - Performance standard.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Performance standard. 250.1600 Section 250.1600 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... conducted in a manner to protect against harm or damage to life (including fish and other aquatic...

  8. 30 CFR 250.504 - Hydrogen sulfide.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Hydrogen sulfide. 250.504 Section 250.504 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... equipment and flow lines, circulating the well, swabbing, and pulling tubing, pumps, and packers. The...

  9. 30 CFR 250.504 - Hydrogen sulfide.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Hydrogen sulfide. 250.504 Section 250.504 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... equipment and flow lines, circulating the well, swabbing, and pulling tubing, pumps, and packers. The...

  10. 30 CFR 250.504 - Hydrogen sulfide.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Hydrogen sulfide. 250.504 Section 250.504 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... equipment and flow lines, circulating the well, swabbing, and pulling tubing, pumps, and packers. The...

  11. 30 CFR 250.604 - Hydrogen sulfide.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Hydrogen sulfide. 250.604 Section 250.604 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... equipment and flow lines, circulating the well, swabbing, and pulling tubing, pumps and packers. The...

  12. 30 CFR 250.604 - Hydrogen sulfide.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Hydrogen sulfide. 250.604 Section 250.604 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... equipment and flow lines, circulating the well, swabbing, and pulling tubing, pumps and packers. The...

  13. 30 CFR 250.604 - Hydrogen sulfide.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Hydrogen sulfide. 250.604 Section 250.604 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... equipment and flow lines, circulating the well, swabbing, and pulling tubing, pumps and packers. The...

  14. 18 CFR 3b.250 - Specific exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Specific exemptions. 3b.250 Section 3b.250 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION..., military service, Federal contracts, or access to classified information, but only to the extent that...

  15. English 304 & Communications 250: Professional Rhetorics

    ERIC Educational Resources Information Center

    Hodgson, Justin

    2009-01-01

    This article provides a course overview of English 304 & Communications 250: Professional Rhetorics. This course was a pilot project instituted at Clemson University in spring of 2008. The project integrally linked English 304 (Business Writing) and Communications 250 (Public Speaking), requiring the same students to be enrolled in both 3…

  16. 30 CFR 250.619 - Wireline operations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Wireline operations. 250.619 Section 250.619 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE... occur shall be contained to prevent pollution. (b) All wireline perforating operations and all...

  17. 30 CFR 250.1500 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Definitions. 250.1500 Section 250.1500 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR..., accident-free, and pollution-free production operations, as well as installation, repair,...

  18. 30 CFR 250.304 - Existing facilities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Existing facilities. 250.304 Section 250.304 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pollution...

  19. 17 CFR 250.1 - Registration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Registration. 250.1 Section... AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General Exemptions § 250.1 Registration. (a) Notification of registration. Notifications of registration pursuant to...

  20. 17 CFR 250.1 - Registration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Registration. 250.1 Section... AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General Exemptions § 250.1 Registration. (a) Notification of registration. Notifications of registration pursuant to...

  1. 30 CFR 250.1634 - Site security.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Site security. 250.1634 Section 250.1634 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... security. (a) All locations where sulphur is produced, measured, or stored shall be operated and...

  2. 30 CFR 250.1634 - Site security.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Site security. 250.1634 Section 250.1634 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... security. (a) All locations where sulphur is produced, measured, or stored shall be operated and...

  3. 30 CFR 250.1634 - Site security.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Site security. 250.1634 Section 250.1634 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... security. (a) All locations where sulphur is produced, measured, or stored shall be operated and...

  4. 30 CFR 250.1621 - Crew instructions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Crew instructions. 250.1621 Section 250.1621 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations...

  5. 30 CFR 250.1613 - Diverter systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Diverter systems. 250.1613 Section 250.1613 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations...

  6. 30 CFR 250.1402 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Definitions. 250.1402 Section 250.1402 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS... applicable laws, with any regulations issued under the OCSLA, or with the terms or provisions of leases...

  7. 30 CFR 250.1402 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Definitions. 250.1402 Section 250.1402 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS... applicable laws, with any regulations issued under the OCSLA, or with the terms or provisions of leases...

  8. 30 CFR 250.1903 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Definitions. 250.1903 Section 250.1903 Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems...

  9. 30 CFR 250.304 - Existing facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Existing facilities. 250.304 Section 250.304 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR... Supervisor supply basic emission data from existing facilities when such data are needed for the updating of...

  10. 44 CFR 206.250 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false General. 206.250 Section 206.250 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE Public Assistance Insurance Requirements §...

  11. 5 CFR 250.301 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Definitions. 250.301 Section 250.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN... agency's management team. This includes anyone with supervisory or managerial duties. Managers are those...

  12. 5 CFR 250.301 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Definitions. 250.301 Section 250.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN... agency's management team. This includes anyone with supervisory or managerial duties. Managers are those...

  13. 5 CFR 250.301 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Definitions. 250.301 Section 250.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN... agency's management team. This includes anyone with supervisory or managerial duties. Managers are those...

  14. 5 CFR 250.301 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Definitions. 250.301 Section 250.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN... agency's management team. This includes anyone with supervisory or managerial duties. Managers are those...

  15. 7 CFR 4279.250 - Feasibility studies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Feasibility studies. 4279.250 Section 4279.250 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery Assistance Loans...

  16. 7 CFR 4279.250 - Feasibility studies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 15 2014-01-01 2014-01-01 false Feasibility studies. 4279.250 Section 4279.250 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery Assistance Loans...

  17. 7 CFR 4279.250 - Feasibility studies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 15 2012-01-01 2012-01-01 false Feasibility studies. 4279.250 Section 4279.250 Agriculture Regulations of the Department of Agriculture (Continued) RURAL BUSINESS-COOPERATIVE SERVICE AND RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING Biorefinery Assistance Loans...

  18. 5 CFR 250.301 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Definitions. 250.301 Section 250.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN... agency's management team. This includes anyone with supervisory or managerial duties. Managers are...

  19. 40 CFR 35.250 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... programs that protect workers, groundwater, and endangered species from pesticide risks and for other... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program...

  20. 40 CFR 35.250 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... programs that protect workers, groundwater, and endangered species from pesticide risks and for other... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program...

  1. 40 CFR 35.250 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... programs that protect workers, groundwater, and endangered species from pesticide risks and for other... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program...

  2. 40 CFR 35.250 - Purpose.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... programs that protect workers, groundwater, and endangered species from pesticide risks and for other... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program...

  3. 40 CFR 35.250 - Purpose.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... programs that protect workers, groundwater, and endangered species from pesticide risks and for other... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program...

  4. 30 CFR 250.1203 - Gas measurement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... calibration; (4) Retain calibration reports at the field location for 2 years, and send the reports to the...) must be accompanied by payment of the service fee listed in § 250.125. The service fees are divided into two levels based on complexity, see table in § 250.1202(a)(1). (2) Design, install, use,...

  5. 30 CFR 250.1203 - Gas measurement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... calibration; (4) Retain calibration reports at the field location for 2 years, and send the reports to the...) must be accompanied by payment of the service fee listed in § 250.125. The service fees are divided into two levels based on complexity, see table in § 250.1202(a)(1). (2) Design, install, use,...

  6. 30 CFR 250.1203 - Gas measurement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... calibration; (4) Retain calibration reports at the field location for 2 years, and send the reports to the...) must be accompanied by payment of the service fee listed in § 250.125. The service fees are divided into two levels based on complexity, see table in § 250.1202(a)(1). (2) Design, install, use,...

  7. 30 CFR 250.1619 - Well records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Well records. 250.1619 Section 250.1619 Mineral... Well records. (a) Complete and accurate records for each well and all well operations shall be retained... if cored and analyzed; the kind, weight, size, grade, and setting depth of casing; all well logs...

  8. Phase II clinical trial using californium 252 fast neutron brachytherapy, external pelvic radiation, and extrafascial hysterectomy in the treatment of bulky, barrel-shaped stage IB cervical cancer.

    PubMed

    van Nagell, J R; Maruyama, Y; Donaldson, E S; Hanson, M B; Gallion, H H; Yoneda, J; Powell, D E; Kryscio, R J; Beach, J L

    1986-05-15

    From June 1977 to June 1983, 32 patients with bulky (greater than 4 cm diameter), barrel-shaped Stage IB cervical cancer were treated at the University of Kentucky Medical Center by a combination of outpatient neutron brachytherapy using californium 252 (252Cf) and external pelvic radiation followed by extrafascial hysterectomy. Nineteen patients had cervical tumors 4 to 6 cm in diameter, and 13 patients had lesions in excess of 6 cm in diameter. A dose of 4500 rad external photon therapy was given from a linear accelerator, and one or two 6-hour 252Cf implants were given during or immediately after external radiation. Extrafascial hysterectomy with bilateral salpingo-oophorectomy was performed 6 weeks after completion of radiation therapy. Complications during and after radiation were minimal and included vaginal stenosis (three) and proctitis (two). Tumor clearance in the hysterectomy specimen was complete in 23 patients (72%) and residual cervical tumor was present in 9 patients (28%). Two patients developed tumor recurrence and died of disease 15 and 27 months after therapy, respectively. Thirty patients remain free of disease 26 to 96 months (median, 52 months) after treatment, and none have been lost to follow-up. The actuarial survival of these patients is 97% at 2 years and 94% at 5 years. Intracavitary neutron therapy is well tolerated and is effective when combined with external radiation and hysterectomy in the treatment of bulky, barrel-shaped Stage IB cervical cancer.

  9. 7 CFR 250.53 - Contract provisions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the recipient agency's meal service in the school year or fiscal year (including both entitlement and... accordance with the contingencies in § 250.51(a); (2) The method and frequency by which crediting will occur...

  10. 30 CFR 250.1204 - Surface commingling.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ....125. The service fees are divided into two levels based on complexity, see table in § 250.1202(a)(1... production through the designated system operator. (b) What are the requirements for a periodic well test...

  11. 30 CFR 250.1204 - Surface commingling.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....125. The service fees are divided into two levels based on complexity, see table in § 250.1202(a)(1... production through the designated system operator. (b) What are the requirements for a periodic well test...

  12. 30 CFR 250.1204 - Surface commingling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ....125. The service fees are divided into two levels based on complexity, see table in § 250.1202(a)(1... production through the designated system operator. (b) What are the requirements for a periodic well test...

  13. 30 CFR 250.1204 - Surface commingling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production... listed in § 250.125. The service fees are divided into two levels based on complexity, see table in §...

  14. 30 CFR 250.1627 - Production requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1627 Production requirements. (a) The lessee shall conduct sulphur production operations in compliance with the...

  15. 30 CFR 250.1600 - Performance standard.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1600 Performance standard. Operations to discover, develop, and produce sulphur in the OCS shall be in accordance...

  16. 30 CFR 250.1600 - Performance standard.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1600 Performance standard. Operations to discover, develop, and produce sulphur in the OCS shall be in accordance...

  17. 30 CFR 250.1600 - Performance standard.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1600 Performance standard. Operations to discover, develop, and produce sulphur in the OCS shall be in accordance...

  18. 30 CFR 250.1627 - Production requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1627 Production requirements. (a) The lessee shall conduct sulphur production operations in compliance with the...

  19. 30 CFR 250.1627 - Production requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1627 Production requirements. (a) The lessee shall conduct sulphur production operations in compliance with the...

  20. 30 CFR 1217.250 - Audits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND INSPECTIONS Other Solid Minerals § 1217.250 Audits. An audit of the lessee's accounts and books... public accountants, and at the expense of the lessee. The lessee shall furnish free of cost...

  1. Combination of external beam radiotherapy and Californium (Cf)-252 neutron intracavity brachytherapy is more effective in control of cervical squamous cell carcinoma than that of cervical adenocarcinoma.

    PubMed

    Xiong, Yanli; Liu, Jia; Chen, Shu; Zhou, Qian; Xu, Wenjing; Tang, Chen; Chen, Yonghong; Yang, Mei; Lei, Xin

    2015-09-01

    The objective of this study was to compare the effect of combined external beam radiotherapy (EBRT) and Californium (Cf)-252 neutron intracavity brachytherapy (ICBT) on cervical squamous versus adenocarcinoma. A total of 106 patients with stage IB-IIIB cervical cancer were accrued between January 2005 and May 2011 and divided into squamous cell carcinoma (SCC) and adenocarcinoma (AC) as a pair with 53 patients in each group according to tumor size, stage, age, and hemoglobin level using matched-pair design. The whole pelvic EBRT was performed with 2 Gy/fraction, 4 fractions/week. The total dose was 48-54 Gy (the center of whole pelvic field was blocked by 4 cm in width after 20-36 Gy). Cf-252 neutron ICBT was delivered with 11 and 12 Gy-eq/f with the total dose at point A of 44 and 48 Gy-eq for SCC and AC patients, respectively. The mean follow-up time was 43 months. The 5-year LC, OS, DFS, LAC rates, and mean survival time were 66.0, 56.6, 52.8.0, 17.0%, and 76.4 ± 6.2 months, respectively, for AC patients, whereas they were 81.1, 69.8, 67.9, 11.3%, and 93.3 ± 4.3 months, respectively, for SCC patients. Furthermore, the early treatment toxicity was mild in both groups, the late treatment complications were mainly radiation-induced proctitis and cystitis, and there were no grade 3 or higher complications. Although the combination of Cf-252 neutron ICBT and EBRT was effective in both histology types of cervical cancer, a more aggressive strategy is needed to control cervical AC.

  2. Californium interrogation prompt neutron (CIPN) instrument for non-destructive assay of spent nuclear fuel-Design concept and experimental demonstration

    NASA Astrophysics Data System (ADS)

    Henzlova, D.; Menlove, H. O.; Rael, C. D.; Trellue, H. R.; Tobin, S. J.; Park, Se-Hwan; Oh, Jong-Myeong; Lee, Seung-Kyu; Ahn, Seong-Kyu; Kwon, In-Chan; Kim, Ho-Dong

    2016-01-01

    This paper presents results of the first experimental demonstration of the Californium Interrogation Prompt Neutron (CIPN) instrument developed within a multi-year effort launched by the Next Generation Safeguards Initiative Spent Fuel Project of the United States Department of Energy. The goals of this project focused on developing viable non-destructive assay techniques with capabilities to improve an independent verification of spent fuel assembly characteristics. For this purpose, the CIPN instrument combines active and passive neutron interrogation, along with passive gamma-ray measurements, to provide three independent observables. This paper describes the initial feasibility demonstration of the CIPN instrument, which involved measurements of four pressurized-water-reactor spent fuel assemblies with different levels of burnup and two initial enrichments. The measurements were performed at the Post-Irradiation Examination Facility at the Korea Atomic Energy Institute in the Republic of Korea. The key aim of the demonstration was to evaluate CIPN instrument performance under realistic deployment conditions, with the focus on a detailed assessment of systematic uncertainties that are best evaluated experimentally. The measurements revealed good positioning reproducibility, as well as a high degree of insensitivity of the CIPN instrument's response to irregularities in a radial burnup profile. Systematic uncertainty of individual CIPN instrument signals due to assembly rotation was found to be <4.5%, even for assemblies with fairly extreme gradients in the radial burnup profile. These features suggest that the CIPN instrument is capable of providing a good representation of assembly average characteristics, independent of assembly orientation in the instrument.

  3. Californium-252 neutron intracavity brachytherapy alone for T1N0 low-lying rectal adenocarcinoma: A definitive anal sphincter-preserving radiotherapy.

    PubMed

    Xiong, Yanli; Shan, Jinlu; Liu, Jia; Zhao, Kewei; Chen, Shu; Xu, Wenjing; Zhou, Qian; Yang, Mei; Lei, Xin

    2017-01-17

    This study evaluated the 4-year results of 32 patients with T1N0 low-lying rectal adenocarcinoma treated solely with californium-252 (Cf-252) neutron intracavity brachytherapy (ICBT). Patients were solicited into the study from January 2008 to June 2011. All the patients had refused surgery or surgery was contraindicated. The patients were treated with Cf-252 neutron ICBT using a novel 3.5-cm diameter off-axis 4-channel intrarectal applicator designed by the authors. The dose reference point was defined on the mucosa surface, with a total dose of 55-62 Gy-eq/4 f (13-16 Gy-eq/f/wk). All the patients completed the radiotherapy in accordance with our protocol. The rectal lesions regressed completely, and the acute rectal toxicity was mild (≤G2). The 4-year local control, overall survival, disease-free survival, and late complication (≥G2) rates were 96.9%, 90.6%, 87.5% and 15.6%, respectively. No severe late complication (≥G3) occurred. The mean follow-up was 56.1 ± 16.0 months. At the end of last follow-up, 29 patients remained alive. The mean survival time was 82.1 ± 2.7 months. Cf-252 neutron ICBT administered as the sole treatment (without surgery) for patients with T1N0 low-lying rectal adenocarcinoma is effective with acceptable late complications. Our study and method offers a definitive anal sphincter-preserving radiotherapy for T1N0 low-lying rectal adenocarcinoma patients.

  4. Californium-252 neutron intracavity brachytherapy alone for T1N0 low-lying rectal adenocarcinoma: A definitive anal sphincter-preserving radiotherapy

    PubMed Central

    Xiong, Yanli; Shan, Jinlu; Liu, Jia; Zhao, Kewei; Chen, Shu; Xu, Wenjing; Zhou, Qian; Yang, Mei; Lei, Xin

    2017-01-01

    This study evaluated the 4-year results of 32 patients with T1N0 low-lying rectal adenocarcinoma treated solely with californium-252 (Cf-252) neutron intracavity brachytherapy (ICBT). Patients were solicited into the study from January 2008 to June 2011. All the patients had refused surgery or surgery was contraindicated. The patients were treated with Cf-252 neutron ICBT using a novel 3.5-cm diameter off-axis 4-channel intrarectal applicator designed by the authors. The dose reference point was defined on the mucosa surface, with a total dose of 55–62 Gy-eq/4 f (13–16 Gy-eq/f/wk). All the patients completed the radiotherapy in accordance with our protocol. The rectal lesions regressed completely, and the acute rectal toxicity was mild (≤G2). The 4-year local control, overall survival, disease-free survival, and late complication (≥G2) rates were 96.9%, 90.6%, 87.5% and 15.6%, respectively. No severe late complication (≥G3) occurred. The mean follow-up was 56.1 ± 16.0 months. At the end of last follow-up, 29 patients remained alive. The mean survival time was 82.1 ± 2.7 months. Cf-252 neutron ICBT administered as the sole treatment (without surgery) for patients with T1N0 low-lying rectal adenocarcinoma is effective with acceptable late complications. Our study and method offers a definitive anal sphincter-preserving radiotherapy for T1N0 low-lying rectal adenocarcinoma patients. PMID:28094790

  5. Californium versus cobalt brachytherapy combined with external-beam radiotherapy for IIB stage cervical cancer: long-term experience of a single institute

    PubMed Central

    Janulionis, Ernestas; Valuckas, Konstantinas Povilas; Samerdokiene, Vitalija; Atkocius, Vydmantas

    2015-01-01

    Purpose The purpose of this paper was to observe and compare long-term curative effects and complications of FIGO stage IIB cervical cancer patients (n = 232) treated with high-dose-rate (HDR) californium (252Cf) neutron or cobalt (60Co) photon intracavitary brachytherapy (ICBT) combined with external-beam radiotherapy (EBRT). Material and methods The EBRT dose to the small pelvis was 50 Gy in both groups. The brachytherapy component of 252Cf or 60Co was added in the 3rd week of EBRT, 5 fractions were performed once per week resulting in a total ICBT dose of 40 Gy/Gyeq (point A). Results Overall survival (OS) at 5, 10 and 15 years was 63.6%, 50.4% and 38.8% in the 252Cf group and 62.2%, 50.5%, 39.9%, in the 60Co group, respectively (p = 0.74). The percentage of tumour recurrence was statistically significantly lower in the 252Cf group with 7.4% versus 17.1% in the 60Co group (p = 0.02). Second primary cancers have developed similarly 9.1% and 8.1% cases for 252Cf and 60Co groups, respectively. Conclusions Our long-term retrospective study comparing 252Cf and 60Co isotopes with brachytherapy in combined treatment of FIGO IIB stage cervix carcinoma patients shows, that overall survival in the both groups are similar. However, the recurrence of tumour was significantly lower in the 252Cf group. The incidence of second primary cancers was similar in both groups. PMID:26622239

  6. Californium versus cobalt brachytherapy combined with external-beam radiotherapy for IIB stage cervical cancer: long-term experience of a single institute.

    PubMed

    Janulionis, Ernestas; Valuckas, Konstantinas Povilas; Liukpetryte, Sarune; Samerdokiene, Vitalija; Atkocius, Vydmantas

    2015-10-01

    The purpose of this paper was to observe and compare long-term curative effects and complications of FIGO stage IIB cervical cancer patients (n = 232) treated with high-dose-rate (HDR) californium ((252)Cf) neutron or cobalt ((60)Co) photon intracavitary brachytherapy (ICBT) combined with external-beam radiotherapy (EBRT). The EBRT dose to the small pelvis was 50 Gy in both groups. The brachytherapy component of (252)Cf or (60)Co was added in the 3(rd) week of EBRT, 5 fractions were performed once per week resulting in a total ICBT dose of 40 Gy/Gyeq (point A). Overall survival (OS) at 5, 10 and 15 years was 63.6%, 50.4% and 38.8% in the (252)Cf group and 62.2%, 50.5%, 39.9%, in the (60)Co group, respectively (p = 0.74). The percentage of tumour recurrence was statistically significantly lower in the (252)Cf group with 7.4% versus 17.1% in the (60)Co group (p = 0.02). Second primary cancers have developed similarly 9.1% and 8.1% cases for (252)Cf and (60)Co groups, respectively. Our long-term retrospective study comparing (252)Cf and (60)Co isotopes with brachytherapy in combined treatment of FIGO IIB stage cervix carcinoma patients shows, that overall survival in the both groups are similar. However, the recurrence of tumour was significantly lower in the (252)Cf group. The incidence of second primary cancers was similar in both groups.

  7. Dietary nucleosides and nucleotides do not affect tumor incidence but reduce amyloidosis incidence in B6C3F1 mice irradiated with californium-252.

    PubMed

    Yokoyama, Hiroomi; Fujiwara, Hiroshi; Watanabe, Hiromitsu

    2004-04-01

    We investigated the effects of a dietary mixture of nucleosides and nucleotides (NS) on the systemic incidence rates of postirradiation carcinogenesis and non-neoplastic lesions in mice. Five-week-old male B6C3F1 mice were fed AIN-76B Purified Diet supplemented with NS for 1 wk and 13 mo before and after irradiation of neutron with californium-252 ((252)Cf); specifically NS was added to the AIN-76B Purified Diet (without nucleotide) to obtain a final concentration of 0%, 0.5%, or 2.5% NS. A commercial stock diet was also given to mice, and half of the mice were irradiated. Both irradiated and non-irradiated mice were used for reference controls. The incidence of liver tumors in each NS group was lower than that in the reference control group (P < 0.01), but there were no differences between the 0%, 0.5%, and 2.5% NS groups. In contrast, the incidence rate of mice with non-neoplastic lesions in the 0% NS group was significantly higher than the reference control group (P < 0.05). This higher incidence of mice with non-neoplastic lesions was significantly decreased upon supplementation of the nucleotide-free diet with 0.5% or 2.5% NS (P < 0.01 and P < 0.05, respectively). Of the non-neoplastic lesions observed, the incidence of amyloidosis was decreased significantly upon supplementation of the nucleotide-free diet with 0.5% NS (P < 0.05). Supplementation of a nucleotide-free diet with NS inhibits the development of non-neoplastic lesions, such as those associated with amyloidosis, without promoting the carcinogenesis induced by (252)Cf irradiation.

  8. Californium interrogation prompt neutron (CIPN) instrument for non-destructive assay of spent nuclear fuel – design concept and experimental demonstration

    DOE PAGES

    Henzlova, Daniela; Menlove, Howard Olsen; Rael, Carlos D.; ...

    2015-10-09

    Our paper presents results of the first experimental demonstration of the Californium Interrogation Prompt Neutron (CIPN) instrument developed within a multi-year effort launched by the Next Generation Safeguards Initiative Spent Fuel Project of the United States Department of Energy. The goals of this project focused on developing viable non-destructive assay techniques with capabilities to improve an independent verification of spent fuel assembly characteristics. For this purpose, the CIPN instrument combines active and passive neutron interrogation, along with passive gamma-ray measurements, to provide three independent observables. We describe the initial feasibility demonstration of the CIPN instrument, which involved measurements of fourmore » pressurized-water-reactor spent fuel assemblies with different levels of burnup and two initial enrichments. The measurements were performed at the Post-Irradiation Examination Facility at the Korea Atomic Energy Institute in the Republic of Korea. The key aim of the demonstration was to evaluate CIPN instrument performance under realistic deployment conditions, with the focus on a detailed assessment of systematic uncertainties that are best evaluated experimentally. The measurements revealed good positioning reproducibility, as well as a high degree of insensitivity of the CIPN instrument's response to irregularities in a radial burnup profile. Systematic uncertainty of individual CIPN instrument signals due to assembly rotation was found to be <4.5%, even for assemblies with fairly extreme gradients in the radial burnup profile. Lastly, these features suggest that the CIPN instrument is capable of providing a good representation of assembly average characteristics, independent of assembly orientation in the instrument.« less

  9. Californium interrogation prompt neutron (CIPN) instrument for non-destructive assay of spent nuclear fuel – design concept and experimental demonstration

    SciTech Connect

    Henzlova, Daniela; Menlove, Howard Olsen; Rael, Carlos D.; Trellue, Holly Renee; Tobin, Stephen Joseph; Park, Se-Hwan; Oh, Jong-Myeong; Lee, Seung-Kyu; Ahn, Seong-Kyu; Kwon, In-Chan; Kim, Ho-Dong

    2015-10-09

    Our paper presents results of the first experimental demonstration of the Californium Interrogation Prompt Neutron (CIPN) instrument developed within a multi-year effort launched by the Next Generation Safeguards Initiative Spent Fuel Project of the United States Department of Energy. The goals of this project focused on developing viable non-destructive assay techniques with capabilities to improve an independent verification of spent fuel assembly characteristics. For this purpose, the CIPN instrument combines active and passive neutron interrogation, along with passive gamma-ray measurements, to provide three independent observables. We describe the initial feasibility demonstration of the CIPN instrument, which involved measurements of four pressurized-water-reactor spent fuel assemblies with different levels of burnup and two initial enrichments. The measurements were performed at the Post-Irradiation Examination Facility at the Korea Atomic Energy Institute in the Republic of Korea. The key aim of the demonstration was to evaluate CIPN instrument performance under realistic deployment conditions, with the focus on a detailed assessment of systematic uncertainties that are best evaluated experimentally. The measurements revealed good positioning reproducibility, as well as a high degree of insensitivity of the CIPN instrument's response to irregularities in a radial burnup profile. Systematic uncertainty of individual CIPN instrument signals due to assembly rotation was found to be <4.5%, even for assemblies with fairly extreme gradients in the radial burnup profile. Lastly, these features suggest that the CIPN instrument is capable of providing a good representation of assembly average characteristics, independent of assembly orientation in the instrument.

  10. 48 CFR 1846.673 - Distribution of DD Forms 250 and 250c.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Distribution of DD Forms 250 and 250c. 1846.673 Section 1846.673 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACT MANAGEMENT QUALITY ASSURANCE Material Inspection and Receiving...

  11. 48 CFR 1846.672 - Preparing DD Forms 250 and 250c.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Preparing DD Forms 250 and 250c. 1846.672 Section 1846.672 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACT MANAGEMENT QUALITY ASSURANCE Material Inspection and Receiving Reports 1846.672 Preparing...

  12. 30 CFR 250.1614 - Mud program.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1614 Mud program. (a) The quantities, characteristics, use, and testing of drilling mud and the...

  13. 30 CFR 250.500 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... § 250.500 General requirements. Well-completion operations shall be conducted in a manner to protect... OCS including any mineral deposits (in areas leased and not leased), the National security or defense, or the marine, coastal, or human environment. ...

  14. 30 CFR 250.600 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... § 250.600 General requirements. Well-workover operations shall be conducted in a manner to protect... Outer Continental Shelf (OCS) including any mineral deposits (in areas leased and not leased), the National security or defense, or the marine, coastal, or human environment. ...

  15. 30 CFR 250.500 - General requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... § 250.500 General requirements. Well-completion operations shall be conducted in a manner to protect... OCS including any mineral deposits (in areas leased and not leased), the National security or defense, or the marine, coastal, or human environment. ...

  16. 30 CFR 250.600 - General requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... § 250.600 General requirements. Well-workover operations shall be conducted in a manner to protect... Outer Continental Shelf (OCS) including any mineral deposits (in areas leased and not leased), the National security or defense, or the marine, coastal, or human environment. ...

  17. 30 CFR 250.500 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... § 250.500 General requirements. Well-completion operations shall be conducted in a manner to protect... OCS including any mineral deposits (in areas leased and not leased), the National security or defense, or the marine, coastal, or human environment. ...

  18. 30 CFR 250.600 - General requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... § 250.600 General requirements. Well-workover operations shall be conducted in a manner to protect... Outer Continental Shelf (OCS) including any mineral deposits (in areas leased and not leased), the National security or defense, or the marine, coastal, or human environment. ...

  19. 21 CFR 172.250 - Petroleum naphtha.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... length in the range of 5,000 centimeters ±0.005 centimeter; also for checking spectrophotometer... the cells, determine any absorbance difference. Spectrophotometer. Spectral range 250-400 mµ with... measurements, the spectrophotometer shall also meet the following performance requirements: Absorbance...

  20. 21 CFR 172.250 - Petroleum naphtha.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... length in the range of 5,000 centimeters ±0.005 centimeter; also for checking spectrophotometer... the cells, determine any absorbance difference. Spectrophotometer. Spectral range 250-400 mµ with... measurements, the spectrophotometer shall also meet the following performance requirements: Absorbance...

  1. 21 CFR 172.250 - Petroleum naphtha.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... length in the range of 5,000 centimeters ±0.005 centimeter; also for checking spectrophotometer... the cells, determine any absorbance difference. Spectrophotometer. Spectral range 250-400 mµ with... measurements, the spectrophotometer shall also meet the following performance requirements: Absorbance...

  2. 21 CFR 172.250 - Petroleum naphtha.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... length in the range of 5,000 centimeters ±0.005 centimeter; also for checking spectrophotometer... the cells, determine any absorbance difference. Spectrophotometer. Spectral range 250-400 mµ with... measurements, the spectrophotometer shall also meet the following performance requirements: Absorbance...

  3. 5 CFR 250.203 - Agency responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MANAGEMENT IN AGENCIES Strategic Human Capital Management § 250.203 Agency responsibilities. (a) To assist in the assessment of the management of human capital in the Federal Government, and to help meet the..., heads of agencies or their designees must maintain a current human capital plan and provide OPM...

  4. 30 CFR 250.300 - Pollution prevention.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pollution Prevention and Control § 250... oil and gas or sulphur, the lessee shall take measures to prevent unauthorized discharge of pollutants..., sand, and other well solids shall be obtained from the District Manager. (3) All hydrocarbon-handling...

  5. 30 CFR 250.300 - Pollution prevention.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pollution Prevention and Control § 250... oil and gas or sulphur, the lessee shall take measures to prevent unauthorized discharge of pollutants..., sand, and other well solids shall be obtained from the District Manager. (3) All hydrocarbon-handling...

  6. 10 CFR 600.250 - Closeout.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... for Grants and Cooperative Agreements to State and Local Governments Post-Award Requirements § 600.250... the expiration or termination of the grant, the grantee must submit all financial, performance, and... extend this timeframe. These may include but are not limited to: (1) Final performance or progress...

  7. 21 CFR 74.250 - Orange B.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL LISTING OF COLOR ADDITIVES SUBJECT TO CERTIFICATION Foods § 74.250 Orange B. (a) Identity. (1) The color additive Orange B is.... (2) The diluents in color additive mixtures for food use containing Orange B are limited to those...

  8. 30 CFR 250.1008 - Reports.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... accompanied by payment of the service fee listed in § 250.125. You must submit a detailed report of the repair... Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS... shall report to the Regional Supervisor any pipeline taken out of service. If the period of time...

  9. 7 CFR 250.19 - Reviews.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... agencies, and processors by monitoring performance reports, food requests, participation data, and data... other information. (ii) An on-site review at least once every 2 years of all processors except those that are multi-State processors as defined in § 250.3, with no fewer than 50 percent being...

  10. 30 CFR 250.1402 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Civil Penalties Outer Continental Shelf Lands Act Civil Penalties § 250.1402 Definitions. Terms used in this... assess civil penalties. Violation means failure to comply with the Outer Continental Shelf Lands...

  11. 30 CFR 250.1402 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Outer Continental Shelf Civil Penalties Outer Continental Shelf Lands Act Civil Penalties § 250.1402 Definitions. Terms used in this subpart have the... penalties. Violation means failure to comply with the Outer Continental Shelf Lands Act (OCSLA) or any...

  12. 30 CFR 250.125 - Service fees.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...—Fixed Structure Under the Platform Approval Program $3,018 § 250.905(k). (18) Platform Application... amended application. (c) Verbal approvals are occasionally given in special circumstances. Any action that will be considered a verbal permit approval requires either a paper permit application to follow...

  13. 30 CFR 250.1008 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pipelines and Pipeline Rights-of-Way § 250.1008 Reports. (a) The... commencing the installation or relocation of a pipeline or conducting a pressure test on a pipeline. (b) The...

  14. 30 CFR 250.1000 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Pipelines and Pipeline Rights-of-Way § 250.1000 General requirements. (a) Pipelines and associated valves, flanges, and fittings shall be designed, installed, operated...

  15. 20 CFR 632.250 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AND TRAINING PROGRAMS Summer Youth Employment and Training Programs § 632.250 General. This subpart contains the policies, rules, and regulations of the Department in implementing and administering a Summer Youth Employment and Training Program for Indians and other Native Americans authorized by title II...

  16. 30 CFR 250.1633 - Production measurement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1633..., installed, used, maintained, and tested so as to accurately and completely measure the sulphur produced on a... production of sulphur until the Regional Supervisor has approved the method of measurement. The request for...

  17. 30 CFR 250.1601 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1601 Definitions. Terms... used to inject air within a sulphur producing well to airlift sulphur out of the well. Bleedwater means.... Bleedwell means a well drilled into a producing sulphur deposit that is used to control the mine pressure...

  18. 30 CFR 250.1633 - Production measurement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1633..., installed, used, maintained, and tested so as to accurately and completely measure the sulphur produced on a... production of sulphur until the Regional Supervisor has approved the method of measurement. The request for...

  19. 30 CFR 250.1600 - Performance standard.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1600 Performance standard. Operations to discover, develop, and produce sulphur in the OCS shall be in accordance with an approved Exploration Plan...

  20. 30 CFR 250.1632 - Production rates.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1632 Production rates. Each sulphur deposit shall be produced at rates that will provide economic development and depletion of the deposit in a manner that would maximize the ultimate recovery of sulphur without resulting...

  1. 30 CFR 250.1632 - Production rates.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1632 Production rates. Each sulphur deposit shall be produced at rates that will provide economic development and depletion of the deposit in a manner that would maximize the ultimate recovery of sulphur without resulting...

  2. 30 CFR 250.1601 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1601 Definitions. Terms... used to inject air within a sulphur producing well to airlift sulphur out of the well. Bleedwater means.... Bleedwell means a well drilled into a producing sulphur deposit that is used to control the mine pressure...

  3. 30 CFR 250.1601 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1601 Definitions. Terms used in this... air within a sulphur producing well to airlift sulphur out of the well. Bleedwater means a mixture of...

  4. 30 CFR 250.1601 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1601... string that is used to inject air within a sulphur producing well to airlift sulphur out of the well.... Bleedwell means a well drilled into a producing sulphur deposit that is used to control the mine pressure...

  5. 30 CFR 250.1602 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1602 Applicability. (a) The requirements... OCS sulphur lease. Sulphur operations include all activities conducted under a lease for the purpose...

  6. 30 CFR 250.1632 - Production rates.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1632 Production rates. Each sulphur deposit shall be produced at rates that will provide economic development and depletion of the deposit in a manner that would maximize the ultimate recovery of sulphur without resulting...

  7. 30 CFR 250.1601 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1601 Definitions. Terms... used to inject air within a sulphur producing well to airlift sulphur out of the well. Bleedwater means.... Bleedwell means a well drilled into a producing sulphur deposit that is used to control the mine pressure...

  8. 30 CFR 250.1634 - Site security.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1634 Site security. (a) All locations where sulphur is produced, measured, or stored shall be operated and maintained to ensure against the...

  9. 30 CFR 250.1633 - Production measurement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Sulphur Operations § 250.1633..., installed, used, maintained, and tested so as to accurately and completely measure the sulphur produced on a... production of sulphur until the Regional Supervisor has approved the method of measurement. The request for...

  10. 7 CFR 250.53 - Contract provisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION DONATION OF FOODS FOR USE IN THE UNITED STATES, ITS... Management Companies § 250.53 Contract provisions. (a) Required contract provisions in fixed-price contracts... recipient agency's fixed-price contract with a food service management company. Such provisions must also...

  11. 30 CFR 250.1903 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250.1903 Definitions. Definitions listed in this section apply to this subpart...

  12. 30 CFR 250.1904 - Special instructions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250.1904 Special instructions. (a) For purposes of this subpart, each and every...

  13. 30 CFR 250.1904 - Special instructions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Mineral Resources BUREAU OF SAFETY AND ENVIRONMENTAL ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Safety and Environmental Management Systems (SEMS) § 250.1904 Special instructions. (a) For purposes of this subpart, each and every...

  14. 5 CFR 250.302 - Survey requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MANAGEMENT IN AGENCIES Employee Surveys § 250.302 Survey requirements. (a) Each executive agency must conduct an annual survey of its employees containing the definitions and each question in this subpart. (b... employee survey questions under paragraph (c) of this section. (c) The definitions and 45 prescribed...

  15. 30 CFR 250.605 - Subsea workovers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.605 Subsea workovers. No subsea well-workover operation including...

  16. 30 CFR 250.606 - Crew instructions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.606 Crew instructions. Prior to engaging in well-workover operations,...

  17. 30 CFR 250.506 - Crew instructions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.506 Crew instructions. Prior to engaging in well-completion operations,...

  18. 30 CFR 250.505 - Subsea completions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.505 Subsea completions. No subsea well completion shall be commenced until...

  19. 32 CFR 250.5 - Procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... judgment that the technical data under consideration disclose critical technology with military or space application. For purposes of making this determination, the Militarily Critical Technologies List (MCTL) shall... explain the intended use of the requested data and, if appropriate, request a new certification (see § 250...

  20. 32 CFR 250.5 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... judgment that the technical data under consideration disclose critical technology with military or space application. For purposes of making this determination, the Militarily Critical Technologies List (MCTL) shall... explain the intended use of the requested data and, if appropriate, request a new certification (see § 250...

  1. Californium-252 (252Cf) versus conventional gamma radiation in the brachytherapy of advanced cervical carcinoma long-term treatment results of a randomized study.

    PubMed

    Tacev, Taco; Ptácková, Blanka; Strnad, Vratislav

    2003-06-01

    When photon radiotherapy is applied to cervical carcinoma, it has been observed that, despite important progress in radiotherapy technique and quality assurance, no significant increase in curative rates has resulted. Among the reasons for this is the varying radiosensitivity of different tumor subpopulations. Treatment with californium-252 ((252)Cf), as a source of gamma/neutron radiation in brachytherapy, provides properties and new treatment modalities that help to overcome this factor. From January 1985 to June 1993, 227 women with stage IIB and IIIB cervical carcinoma were treated in a randomized brachytherapy study as follows: (1) 117 patients (55 with stage IIB, 62 with stage IIIB) were treated with (252)Cf during the 1st week of therapy by 6 Gy (40 Gy-eq) of the neutron component in point A. Supplementation by a 16-Gy dose with (226)Ra or (137)Cs was done in the 5th week. (2) 110 patients (50 with stage IIB, 60 with stage IIIB) were treated solely by gamma radiation ((226)Ra or (137)Cs). A dose of 56 Gy in point A was applied in two fractions at the 3rd and 5th week, respectively. The dose of 56 Gy-equivalents was completed by external radiation with 40 Gy. The total radiation doses at points A and B amounted to 85 Gy and 59 Gy, respectively. The treatment results were compared. The overall 5-year survival rate for all stages IIB and IIIB was better by 18.9% for (252)Cf patients than for patients receiving conventional treatment (75.2% vs. 56.3%, respectively; p < 0.001). In the stage IIIB (252)Cf group, it was significantly better by 22.8% than for the conventional group (66.1% vs. 43.3%, respectively; p < 0.003). The higher survival rate in (252)Cf patients was the result of significantly less local relapses compared with patients treated conventionally (12,8% vs. 31.8%; p < 0.0009). The importance of neutron source (252)Cf in the brachytherapy of cervical carcinoma by overcoming the tumor resistance to conventional photon irradiation has been confirmed.

  2. 30 CFR 250.1200 - Question index table.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Question index table. 250.1200 Section 250.1200..., Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists...(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b) 21...

  3. 30 CFR 250.1200 - Question index table.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Question index table. 250.1200 Section 250.1200..., Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists...(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b) 21...

  4. 30 CFR 250.1200 - Question index table.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Question index table. 250.1200 Section 250.1200..., Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists...(a) 20. What are the requirements for a periodic well test used for allocation? § 250.1204(b) 21...

  5. Generation of chimeric bispecific G250/anti-CD3 monoclonal antibody, a tool to combat renal cell carcinoma.

    PubMed Central

    Luiten, R. M.; Coney, L. R.; Fleuren, G. J.; Warnaar, S. O.; Litvinov, S. V.

    1996-01-01

    The monoclonal antibody (MAb) G250 binds to a tumour-associated antigen, expressed in renal cell carcinoma (RCC), which has been demonstrated to be a suitable target for antibody-mediated immunotherapy. A bispecific antibody having both G250 and anti-CD3 specificity can cross-link G250 antigen-expressing RCC target cells with T cells and can mediate lysis of such targets. Therapy studies with murine antibodies are limited by immune responses to the antibodies injected (HAMA response), which can be decreased by using chimeric antibodies. We generated a chimeric bispecific G250/anti CD3 MAb by transfecting chimeric genes of heavy and light chains for both the G250 MAb and the anti-CD3 MAb into a myeloma cell line. Cytotoxicity assays revealed that the chimeric bispecific MAb was capable of mediating lysis of RCC cell lines by cloned human CD8+T cells or by IL-2-stimulated peripheral blood lymphocytes (PBLs). Lysis mediated by the MAb was specific for target cells that expressed the G250 antigen and was effective at concentrations as low as 0.01 microgram ml-1. The chimeric bispecific G250/anti-CD3 MAb produced may be an effective adjuvant to the currently used IL-2-based therapy of advanced renal cell arcinoma. Images Figure 7 PMID:8795576

  6. Development of 250W EUV light source for HVM lithography

    NASA Astrophysics Data System (ADS)

    Mizoguchi, Hakaru; Nakarai, Hiroaki; Abe, Tamotsu; Nowak, Krzysztof M.; Kawasuji, , Yasufumi; Tanaka, Hiroshi; Watanabe, Yukio; Hori, Tsukasa; Kodama, Takeshi; Shiraishi, Yutaka; Yanagida, Tatsuya; Yamada, Tsuyoshi; Yamazaki, Taku; Okazaki, Shinji; Saitou, Takashi

    2017-02-01

    We have been developing CO2-Sn-LPP EUV light source which is the most promising solution as the 13.5nm high power light source for HVM EUVL since 2003. Unique original technologies such as; combination of pulsed CO2 laser and Sn droplets, dual wavelength laser pulse shooting and mitigation with magnetic field have been developed in Gigaphoton Inc.. The theoretical and experimental data have clearly showed the advantage of our proposed strategy. We demonstrated 117W EUV power (I/F clean in burst), 50 kHz, 22 hours stable operation at Pilot #1 device. Target of this device is 250 W EUV power by 27 kW pulsed CO2 driver laser system.

  7. ACCELERATING POLARIZED PROTONS TO 250 GEV

    SciTech Connect

    BAI,M.; AHRENS, L.; ALEKSEEV, I.G.; ALESSI, J.; BEEBE-WANG, J.; ET AL.

    2007-06-25

    The Relativistic Heavy Ion Collider (RHIC) as the first high energy polarized proton collider was designed t o provide polarized proton collisions a t a maximum beam energy of 250 GeV. I t has been providing collisions a t a beam energy of 100 Gel' since 2001. Equipped with two full Siberian snakes in each ring, polarization is preserved during the acceleration from injection to 100 GeV with careful control of the betatron tunes and the vertical orbit distortions. However, the intrinsic spin resonances beyond 100 GeV are about a factor of two stronger than those below 100 GeV? making it important t o examine the impact of these strong intrinsic spin resonances on polarization survival and the tolerance for vertical orbit distortions. Polarized protons were accelerated t o the record energy of 250 GeV in RHIC with a polarization of 46% measured a t top energy in 2006. The polarization measurement as a function of beam energy also shows some polarization loss around 136 GeV, the first strong intrinsic resonance above 100 GeV. This paper presents the results and discusses the sensitivity of the polarization survival t o orbit distortions.

  8. Hypoxic versus normoxic external-beam irradiation of cervical carcinoma combined with californium-252 neutron brachytherapy. Comparative treatment results of a 5-year randomized study.

    PubMed

    Tacev, Taco; Vacek, Antonín; Ptácková, Blanka; Strnad, Vratislav

    2005-05-01

    The article focuses on the treatment and protective effects of hypoxyradiotherapy during external-beam irradiation of cervical carcinoma, including paraaortic lymph nodes, combining radiotherapy with californium-252 ((252)Cf) neutron brachytherapy. An analysis of treatment results, early and late side effects and complications is presented. From January 1989 to May 1997, 307 women with stage IIb and IIIb cervical carcinoma, treated with (252)Cf neutron brachytherapy, were randomly divided into two groups and treated with external-beam irradiation to the paraaortic lymph nodes as follows: 155 patients (59 with stage IIb, 96 with stage IIIb) were treated by external-beam irradiation administered as a 60-Gy dose applied under conditions of acute hypoxia; 77 patients (30 with stage IIb and 47 with stage IIIb) received extended-field irradiation up to L4 and 78 patients (29 with stage IIb and 49 with stage IIIb) up to T12. 152 patients (58 with stage IIb, 94 with stage IIIb) were treated by external-beam irradiation administered as a 40-Gy dose applied under normal oxygenation conditions. 73 patients (29 with stage IIb and 44 with stage IIIb) received extended-field irradiaton up to L4 and 79 patients (29 with stage IIb and 50 with stage IIIb) up to T12. The same 56 Gy-equivalent (eq) doses at point A and 19 Gy-eq doses at point B were applied intracavitarily in both groups. The total radiation doses at points A and B were 99 and 79 Gy-eq, respectively, for patients treated with external-beam irradiation to 60 Gy under conditions of acute hypoxia. For patients treated with external-beam irradiation to 40 Gy under normal oxygenation conditions, the doses at points A and B were 85 and 59 Gy-eq, respectively. The 5-year overall survival rate for all patients (stages IIb and IIIb) was 7.0% better for patients treated in acute hypoxia than for patients treated under normal oxygenation conditions (78.7% vs. 71.7% [p < 0.16]). The 5-year metastases-free survival rate was

  9. [Ombrelle 250: a new contraceptive intrauterine device].

    PubMed

    Audebert, A J

    1986-10-01

    The umbrella 250 is a new IUD developed in France to minimize rigidity and penetration of the uterine wall so as to lessen side effects of local pain and bleeding. The flexible, supple vactor has the characteristics of a spring to ensure that it remains in place in the fundal position required for efficacy. The device is in the shape of a T whose vertical branch is coated with copper threads containing 250 sq mm of copper. The umbrella 250 comes in 1 size, 31.5 mm long, and is adaptable to any uterine cavity. The cumulative rates of events per 100 women after 12, 24, and 36 months respectively were .2, .9, and .9 for pregnancy; .6, .6, and .6 for expulsion; 1.9, 3.7, and 4.0 for removal for pain or bleeding; .8, 1.7, and 2.8 for removal for other medical reason; 1.7, 5.7, and 7.0 for removal to become pregnant; and .2, 1.2, and 1.4 for removal for personal reasons. The continuation rates were 95.1, 87.0, and 83.9 after 12, 24, and 36 months. There were 461, 373, and 149 insertions and 5755, 10,813, and 13,768 women-months of use in each of the 3 years. A multicenter study covering 925 insertions after 12 months showed 2 accidental pregnancies, 4 expulsions, 27 removals for pain and bleeding, 6 removals for infection, 10 removals for other medical reasons, and 16 removals to become pregnant. 89 patients were lost to follow-up. The continuation rate was 92, and the experience covered 9054 women-months of use. The patients were selected according to the usual criteria for IUD use. Most patients had at least 1 child and were at least 30 years old. The rates of expulsion and removal for pain and bleeding appear to be low, but a true comparative study has not been completed.

  10. Contextual view of Building 250 along C Street, view facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of Building 250 along C Street, view facing southwest - U.S. Marine Corps Base Hawaii, Kaneohe Bay, Warehouse 250, Aviation Storehouse, C Street between Fifth & Sixth Streets, Kaneohe, Honolulu County, HI

  11. 32 CFR 250.2 - Applicability and scope.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Traffic in Arms Regulations (ITAR). (2) Introduce any additional controls on the dissemination of... (see § 250.7) or for general exemptions under 22 CFR 125.11 of the ITAR (see § 250.8). (4) Alter...

  12. 32 CFR 250.2 - Applicability and scope.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Traffic in Arms Regulations (ITAR). (2) Introduce any additional controls on the dissemination of... (see § 250.7) or for general exemptions under 22 CFR 125.11 of the ITAR (see § 250.8). (4) Alter...

  13. 32 CFR 250.2 - Applicability and scope.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Traffic in Arms Regulations (ITAR). (2) Introduce any additional controls on the dissemination of... (see § 250.7) or for general exemptions under 22 CFR 125.11 of the ITAR (see § 250.8). (4) Alter...

  14. 32 CFR 250.2 - Applicability and scope.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Traffic in Arms Regulations (ITAR). (2) Introduce any additional controls on the dissemination of... (see § 250.7) or for general exemptions under 22 CFR 125.11 of the ITAR (see § 250.8). (4) Alter...

  15. Characteristics of spontaneous fission of 250No

    NASA Astrophysics Data System (ADS)

    Svirikhin, A. I.; Andreev, A. V.; Yeremin, A. V.; Izosimov, I. N.; Isaev, A. V.; Kuznetsov, A. N.; Kuznetsova, A. A.; Malyshev, O. N.; Popeko, A. G.; Popov, Y. A.; Sokol, E. A.; Chelnokov, M. L.; Chepigin, V. I.; Schneidman, T. M.; Gall, B.; Dorvaux, O.; Brione, P.; Hauschild, K.; Lopez-Martenz, A.; Rezynkina, K.; Mullins, S.; Jones, P.; Mosat, P.

    2017-07-01

    This study describes an experiment on investigating the properties of spontaneous fission of shortlived neutron-deficient nuclei synthesized in the reaction of complete fusion 48Ca + 204Pb = 252No*. The experiment is performed using the SHELS separator and the beam of multicharged ions at U-400 accelerator (LNR, JINR). Two activities undergoing spontaneous fission, which can be related to the ground and isomeric states of 250No nucleus, are registered. The half-lives, total kinetic energies of fission fragments, and neutron multiplicities are measured for the short-lived nuclei. The average number of neutrons per fission for the activity with t 1/2 = 5.1 ± 0.3 μs is = 4.38 ± 0.13 μs, and for nuclei with the half-life t 1/2 = 36 ± 3 μs it is xxxxx.

  16. Photosensitivity: results of investigation in 250 patients.

    PubMed Central

    Wasserman, G. A.; Haberman, H. F.

    1975-01-01

    Between January 1972 and December 1974, 250 patients were referred for investigation of possible photosensitivity to a university-associated clinical research unit for photobiology. In addition to an appropriate history and clinical examination, phototesting was carried out with a solar simulator, monochromatic light and fluorescent light directed to patch-tested areas of skin. Photosensitivity was not demonstrated in 110 patients (44%). Among the laboratory-confirmed photosensitivities, diagnoses included polymorphous light eruption (4.4%), erythropoietic protoporphyria (3.6%), porphyria cutanea tarda (2%), photoallergic contact dermatitis (5.6%), persistent light reaction (4%), systemic drug phototoxicity (1.2%), phototoxic contact dermatitis (2%), solar urticaria (0.8%) and photoaggravated dermatoses (7.6%). It is important to establish a precise etiologic diagnosis in patients with photosensitivity in order to treat the disorder specifically or effectively or both. PMID:1201541

  17. 7 CFR 58.250 - Dry whole milk.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Dry whole milk. 58.250 Section 58.250 Agriculture... Products Bearing Usda Official Identification § 58.250 Dry whole milk. Dry whole milk in commercial bulk... Grades of Dry Whole Milk. Quality requirements for dry whole milk in consumer packages shall be for...

  18. 6 CFR 27.250 - Inspections and audits.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Inspections and audits. 27.250 Section 27.250 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.250 Inspections and audits. (a) Authority. In order...

  19. 6 CFR 27.250 - Inspections and audits.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 6 Domestic Security 1 2014-01-01 2014-01-01 false Inspections and audits. 27.250 Section 27.250 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CHEMICAL FACILITY ANTI-TERRORISM STANDARDS Chemical Facility Security Program § 27.250 Inspections and audits. (a) Authority. In order...

  20. 7 CFR 958.250 - Assessment Credit Report.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Assessment Credit Report. 958.250 Section 958.250... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Rules and Regulations § 958.250 Assessment Credit Report. Each handler may receive a credit for assessments on onions that have been levied in...

  1. 7 CFR 958.250 - Assessment Credit Report.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Assessment Credit Report. 958.250 Section 958.250... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Rules and Regulations § 958.250 Assessment Credit Report. Each handler may receive a credit for assessments on onions that have been levied in...

  2. 30 CFR 250.1200 - Question index table.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Measurement, Surface Commingling, and Security § 250.1200 Question index table. The table in this section lists questions concerning Oil and Gas... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Question index table. 250.1200 Section 250.1200...

  3. 30 CFR 250.1200 - Question index table.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Production Measurement, Surface Commingling, and Security § 250.1200 Question index table. The table in this section... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Question index table. 250.1200 Section 250.1200...

  4. 30 CFR 250.612 - Field well-workover rules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Field well-workover rules. 250.612 Section 250.612 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.612 Field...

  5. 30 CFR 250.612 - Field well-workover rules.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Field well-workover rules. 250.612 Section 250... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.612 Field well-workover rules. When geological and engineering information available in a...

  6. 30 CFR 250.612 - Field well-workover rules.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Field well-workover rules. 250.612 Section 250... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.612 Field well-workover rules. When geological and engineering information available in a...

  7. 30 CFR 250.512 - Field well-completion rules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Field well-completion rules. 250.512 Section 250.512 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.512...

  8. 30 CFR 250.612 - Field well-workover rules.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Field well-workover rules. 250.612 Section 250... THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.612 Field well-workover rules. When geological and engineering...

  9. 30 CFR 250.612 - Field well-workover rules.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Field well-workover rules. 250.612 Section 250... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.612 Field well-workover rules. When geological and engineering information available in a...

  10. 7 CFR 250.68 - Nutrition Services Incentive Program (NSIP).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Nutrition Services Incentive Program (NSIP). 250.68 Section 250.68 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION... Donated Food Outlets § 250.68 Nutrition Services Incentive Program (NSIP). (a) Distribution of donated...

  11. 40 CFR 272.250-272.299 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 27 2011-07-01 2011-07-01 false 272.250-272.299 Section 272.250-272.299 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS California §§ 272.250-272.299...

  12. 40 CFR 272.250-272.299 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false 272.250-272.299 Section 272.250-272.299 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS California §§ 272.250-272.299...

  13. 7 CFR 1951.250 - OMB control number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 14 2014-01-01 2014-01-01 false OMB control number. 1951.250 Section 1951.250... Programs Loans and Grants § 1951.250 OMB control number. The reporting and recordkeeping requirements... assigned OMB Control Number 0575-0066. Public reporting burden for this collection of information is...

  14. 30 CFR 250.503 - Emergency shutdown system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Emergency shutdown system. 250.503 Section 250.503 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Completion Operations § 250.503...

  15. 30 CFR 250.603 - Emergency shutdown system.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Emergency shutdown system. 250.603 Section 250.603 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Oil and Gas Well-Workover Operations § 250.603 Emergency...

  16. 30 CFR 202.250 - Overriding royalty interest.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Overriding royalty interest. 202.250 Section 202.250 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT ROYALTIES Coal § 202.250 Overriding royalty interest. The regulations governing overriding...

  17. 30 CFR 250.510 - Diesel engine air intakes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Diesel engine air intakes. 250.510 Section 250... Operations § 250.510 Diesel engine air intakes. Diesel engine air intakes must be equipped with a device to shut down the diesel engine in the event of runaway. Diesel engines that are continuously attended...

  18. 30 CFR 250.610 - Diesel engine air intakes.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Diesel engine air intakes. 250.610 Section 250... Operations § 250.610 Diesel engine air intakes. No later than May 31, 1989, diesel engine air intakes shall be equipped with a device to shut down the diesel engine in the event of runaway. Diesel...

  19. 30 CFR 250.610 - Diesel engine air intakes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Diesel engine air intakes. 250.610 Section 250... Operations § 250.610 Diesel engine air intakes. No later than May 31, 1989, diesel engine air intakes shall be equipped with a device to shut down the diesel engine in the event of runaway. Diesel...

  20. 30 CFR 250.510 - Diesel engine air intakes.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Diesel engine air intakes. 250.510 Section 250... Operations § 250.510 Diesel engine air intakes. Diesel engine air intakes must be equipped with a device to shut down the diesel engine in the event of runaway. Diesel engines that are continuously attended...