Guidelines for Establishing and Evaluating High School Technical Electromechanics Programs.

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Div. of Vocational, Technical and Adult Education.

Educators and industrial representatives developed these guidelines for school officials, instructors in technical education, and program and facility planners to use in planning a high school program in technical electromechanics. Designed to train students for entry into industry in applied electromechanics, the program includes electricity,…

75 FR 20358 - Intra-Agency Appeal Process: Guidelines for Appeals of Material Supervisory Determinations and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-19

... decisional deadline for written decisions by the SARC. Also, both the SARC Guidelines and the AAC Guidelines have been amended to make additional, limited technical clarifying and conforming amendments. Both sets... action or decision, and to make limited technical amendments. (73 FR 54822 (Sept. 23, 2008)). Although...

Technical guidelines for environmental dredging of contaminated sediments

DOT National Transportation Integrated Search

2008-09-01

This report provides technical guidelines for evaluating : environmental dredging as a sediment remedy component. This document : supports the Contaminated Sediment Remediation Guidance for : Hazardous Waste Sites, released by the U.S. Environmental ...

Translations on USSR Science and Technology, Physical Sciences and Technology, Number 51

DTIC Science & Technology

1978-09-27

Leningrad) Kuznetsov , Mikhail Vladimirovich, engineer (Moscow) Kulayev, Konstantin Vladimirovich, candidate of technical sciences, deputy minister...Ministry of Railroads of the USSR (Moscow) Kushner, Eduard Fedorovich, candidate of technical sciences, IK AN USSR (Kiev) Lisov, Oleg Ivanovich

Technical Review Guidelines for Environmental Impact Assessments in the Tourism, Energy and Mining Sectors

EPA Pesticide Factsheets

EPA coordinated a regional collaborative process with Central America and Dominican Republic Free Trade Agreement (CAFTA-DR) partners to develop Environmental Impact Assessment (EIA) Technical Review Guidelines for three sectors.

10 CFR Appendix III to Part 960 - Application of the System and Technical Guidelines During the Siting Process

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Application of the System and Technical Guidelines During the Siting Process III Appendix III to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. III Appendix III to Part...

10 CFR Appendix III to Part 960 - Application of the System and Technical Guidelines During the Siting Process

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Application of the System and Technical Guidelines During the Siting Process III Appendix III to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. III Appendix III to Part...

10 CFR Appendix III to Part 960 - Application of the System and Technical Guidelines During the Siting Process

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Application of the System and Technical Guidelines During the Siting Process III Appendix III to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. III Appendix III to Part...

10 CFR Appendix III to Part 960 - Application of the System and Technical Guidelines During the Siting Process

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Application of the System and Technical Guidelines During the Siting Process III Appendix III to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. III Appendix III to Part...

USSR Report Engineering and Equipment.

DTIC Science & Technology

1987-05-04

Korenev , et al. ; ENERGETICHESKOYE STROITELSTVO, No 7, Jul 86) 33 Improving Fire Protection of Cables in Electric Power Plants (S.Ye. Korshunov...Russian No 7, Jul 86 pp 32-33 {Article by V.D. Likhachev, candidate of technical sciences, K.I. Korenev , candidate of technical sciences, K.I. Chikvaidze

Online consensus conferences for clinical guidelines development - a survey among participants from the International Guidelines for the Treatment of Actinic Keratosis.

PubMed

Werner, Ricardo N; Jacobs, Anja; Rosumeck, Stefanie; Nast, Alexander

2014-12-01

Guideline development requires considerable time and financial resources. New technical devices such as software for online conferences may help to reduce time and financial efforts of guidelines development. The present survey may serve as an explorative pilot for a future study to determine the technical feasibility, acceptability and possible weaknesses of online consensus conferences for clinical guidelines development. An anonymous online survey was conducted among participants in the online consensus conference of the International League of Dermatological Societies (ILDS) Guidelines for the Treatment of Actinic Keratosis. The majority of participants reported no technical problems with the participation in the online consensus conference; one participant had substantial technical problems accountable to a regional telephone breakdown. The majority of participants would not have preferred a traditional face-to-face conference, and all participants rated online consensus conferences for international guidelines as absolutely acceptable. Rates of acceptance were particularly high among those participants with prior experience with consensus conferences. Certain aspects, particularly the possibilities of debating, were rated as possibly superior in face-to-face conferences by some participants. The data from the online survey indicate that online consensus conferences may be an appropriate alternative to traditional face-to-face consensus conferences, especially within the frame of international guidelines that would require high travel costs and time. Further research is necessary to confirm the data from this explorative pilot study. © 2014 John Wiley & Sons, Ltd.

Advanced missions safety. Volume 2: Technical discussion, Part 2: Experiment safety, guidelines

NASA Technical Reports Server (NTRS)

Hinton, M. G., Jr.

1972-01-01

A technical analysis of a portion of the advanced missions safety study is presented. The potential hazards introduced when experimental equipment is carried aboard the Earth Orbit Shuttle are identified. Safety guidelines and requirements for eliminating or reducing these hazards are recommended.

Learning, techniques, and complications of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline.

PubMed

Polkowski, M; Larghi, A; Weynand, B; Boustière, C; Giovannini, M; Pujol, B; Dumonceau, J-M

2012-02-01

This article is the second of a two-part publication that expresses the current view of the European Society of Gastrointestinal Endoscopy (ESGE) about endoscopic ultrasound (EUS)-guided sampling, including EUS-guided fine needle aspiration (EUS-FNA) and EUS-guided Trucut biopsy. The first part (the Clinical Guideline) focused on the results obtained with EUS-guided sampling, and the role of this technique in patient management, and made recommendations on circumstances that warrant its use. The current Technical Guideline discusses issues related to learning, techniques, and complications of EUS-guided sampling, and to processing of specimens. Technical issues related to maximizing the diagnostic yield (e.g., rapid on-site cytopathological evaluation, needle diameter, microcore isolation for histopathological examination, and adequate number of needle passes) are discussed and recommendations are made for various settings, including solid and cystic pancreatic lesions, submucosal tumors, and lymph nodes. The target readership for the Clinical Guideline mostly includes gastroenterologists, oncologists, internists, and surgeons while the Technical Guideline should be most useful to endoscopists who perform EUS-guided sampling. A two-page executive summary of evidence statements and recommendations is provided. © Georg Thieme Verlag KG Stuttgart · New York.

Space station pressurized laboratory safety guidelines

NASA Technical Reports Server (NTRS)

Mcgonigal, Les

1990-01-01

Before technical safety guidelines and requirements are established, a common understanding of their origin and importance must be shared between Space Station Program Management, the User Community, and the Safety organizations involved. Safety guidelines and requirements are driven by the nature of the experiments, and the degree of crew interaction. Hazard identification; development of technical safety requirements; operating procedures and constraints; provision of training and education; conduct of reviews and evaluations; and emergency preplanning are briefly discussed.

KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors.

PubMed

Lentine, Krista L; Kasiske, Bertram L; Levey, Andrew S; Adams, Patricia L; Alberú, Josefina; Bakr, Mohamed A; Gallon, Lorenzo; Garvey, Catherine A; Guleria, Sandeep; Li, Philip Kam-Tao; Segev, Dorry L; Taler, Sandra J; Tanabe, Kazunari; Wright, Linda; Zeier, Martin G; Cheung, Michael; Garg, Amit X

2017-08-01

The 2017 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors is intended to assist medical professionals who evaluate living kidney donor candidates and provide care before, during and after donation. The guideline development process followed the Grades of Recommendation Assessment, Development, and Evaluation (GRADE) approach and guideline recommendations are based on systematic reviews of relevant studies that included critical appraisal of the quality of the evidence and the strength of recommendations. However, many recommendations, for which there was no evidence or no systematic search for evidence was undertaken by the Evidence Review Team, were issued as ungraded expert opinion recommendations. The guideline work group concluded that a comprehensive approach to risk assessment should replace decisions based on assessments of single risk factors in isolation. Original data analyses were undertaken to produce a "proof-in-concept" risk-prediction model for kidney failure to support a framework for quantitative risk assessment in the donor candidate evaluation and defensible shared decision making. This framework is grounded in the simultaneous consideration of each candidate's profile of demographic and health characteristics. The processes and framework for the donor candidate evaluation are presented, along with recommendations for optimal care before, during, and after donation. Limitations of the evidence are discussed, especially regarding the lack of definitive prospective studies and clinical outcome trials. Suggestions for future research, including the need for continued refinement of long-term risk prediction and novel approaches to estimating donation-attributable risks, are also provided.In citing this document, the following format should be used: Kidney Disease: Improving Global Outcomes (KDIGO) Living Kidney Donor Work Group. KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors. Transplantation. 2017;101(Suppl 8S):S1-S109.

14 CFR 151.72 - Incorporation by reference of technical guidelines in Advisory Circulars.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Incorporation by reference of technical guidelines in Advisory Circulars. 151.72 Section 151.72 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS Project Programming Standards § 151...

14 CFR 151.72 - Incorporation by reference of technical guidelines in Advisory Circulars.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Incorporation by reference of technical guidelines in Advisory Circulars. 151.72 Section 151.72 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS Project Programming Standards § 151...

14 CFR 151.72 - Incorporation by reference of technical guidelines in Advisory Circulars.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Incorporation by reference of technical guidelines in Advisory Circulars. 151.72 Section 151.72 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS Project Programming Standards § 151...

46 CFR Appendix B to Subpart C of... - Substance Technical Guidelines, Benzene

Code of Federal Regulations, 2013 CFR

2013-10-01

... Subpart C of Part 197—Substance Technical Guidelines, Benzene I. Physical and Chemical Data (a) Substance...) Extinguishing media: Carbon dioxide, dry chemical, or foam. (5) Special fire fighting procedures: Do not use a... engineering). (b) Reactivity. (1) Conditions contributing to instability: Heat. (2) Incompatibility: Heat and...

14 CFR 151.72 - Incorporation by reference of technical guidelines in Advisory Circulars.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Incorporation by reference of technical guidelines in Advisory Circulars. 151.72 Section 151.72 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS Project Programming Standards § 151...

14 CFR 151.72 - Incorporation by reference of technical guidelines in Advisory Circulars.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Incorporation by reference of technical guidelines in Advisory Circulars. 151.72 Section 151.72 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRPORTS FEDERAL AID TO AIRPORTS Project Programming Standards § 151...

Guidelines in preparing computer-generated plots for NASA technical reports with the LaRC graphics output system

NASA Technical Reports Server (NTRS)

Taylor, N. L.

1983-01-01

To response to a need for improved computer-generated plots that are acceptable to the Langley publication process, the LaRC Graphics Output System has been modified to encompass the publication requirements, and a guideline has been established. This guideline deals only with the publication requirements of computer-generated plots. This report explains the capability that authors of NASA technical reports can use to obtain publication--quality computer-generated plots or the Langley publication process. The rules applied in developing this guideline and examples illustrating the rules are included.

Cooperative Education Guidelines for Technical Colleges and Other Associate Degree Programs.

ERIC Educational Resources Information Center

Streb, Thomas C.; Hammen, William C.

Guidelines for cooperative education in two-year technical colleges as well as for other associate degree programs are presented in this 15 chapter manual. Chapter 1 covers cooperative education history, current status, advantages and disadvantages, purposes, and information sources. Chapter 2 on personnel presents an overview and discusses the…

A Handbook for Public Playground Safety. Volume II: Technical Guidelines for Equipment and Surfacing.

ERIC Educational Resources Information Center

Consumer Product Safety Commission, Washington, DC.

This handbook suggests safety guidelines for public playground equipment and describes various surfaces used under the equipment and possible injuries resulting from falls. The handbook is intended for use mainly by manufacturers, installers, school and park officials, and others interested in technical criteria for public playground equipment.…

Teaching the History of Technical Communication: A Lesson with Franklin and Hoover.

ERIC Educational Resources Information Center

Todd, Jeff

2003-01-01

Provides and defends four guidelines as a foundation to study ways to incorporate history into classroom lessons: maintain a continued research interest in teaching history; limit to technical rather than scientific discourse; focus on English-language texts; and focus on American texts, authors, and practices. Works within the guidelines to show…

Lightning Protection Guidelines for Aerospace Vehicles

NASA Technical Reports Server (NTRS)

Goodloe, C. C.

1999-01-01

This technical memorandum provides lightning protection engineering guidelines and technical procedures used by the George C. Marshall Space Flight Center (MSFC) Electromagnetics and Aerospace Environments Branch for aerospace vehicles. The overviews illustrate the technical support available to project managers, chief engineers, and design engineers to ensure that aerospace vehicles managed by MSFC are adequately protected from direct and indirect effects of lightning. Generic descriptions of the lightning environment and vehicle protection technical processes are presented. More specific aerospace vehicle requirements for lightning protection design, performance, and interface characteristics are available upon request to the MSFC Electromagnetics and Aerospace Environments Branch, mail code EL23.

Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 Revised Edition

PubMed Central

Song, Kyung Ho; Jung, Hye-Kyung; Kim, Hyun Jin; Koo, Hoon Sup; Kwon, Yong Hwan; Shin, Hyun Duk; Lim, Hyun Chul; Shin, Jeong Eun; Kim, Sung Eun; Cho, Dae Hyeon; Kim, Jeong Hwan; Kim, Hyun Jung

2018-01-01

In 2011, the Korean Society of Neurogastroenterology and Motility (KSNM) published clinical practice guidelines on the management of irritable bowel syndrome (IBS) based on a systematic review of the literature. The KSNM planned to update the clinical practice guidelines to support primary physicians, reduce the socioeconomic burden of IBS, and reflect advances in the pathophysiology and management of IBS. The present revised version of the guidelines is in continuity with the previous version and targets adults diagnosed with, or suspected to have, IBS. A librarian created a literature search query, and a systematic review was conducted to identify candidate guidelines. Feasible documents were verified based on predetermined inclusion and exclusion criteria. The candidate seed guidelines were fully evaluated by the Guidelines Development Committee using the Appraisal of Guidelines for Research and Evaluation II quality assessment tool. After selecting 7 seed guidelines, the committee prepared evidence summaries to generate data exaction tables. These summaries comprised the 4 main themes of this version of the guidelines: colonoscopy; a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols; probiotics; and rifaximin. To adopt the core recommendations of the guidelines, the Delphi technique (ie, a panel of experts on IBS) was used. To enhance dissemination of the clinical practice guidelines, a Korean version will be made available, and a food calendar for patients with IBS is produced. PMID:29605976

EVALUATION GUIDELINES FOR ECOLOGICAL INDICATORS

EPA Science Inventory

This document presents fifteen technical guidelines to evaluate the suitability of an ecological indicator for a particular monitoring program. The guidelines are organized within four evaluation phrases: conceptual relevance, feasibility of implementation, response variability...

37 CFR Appendix A to Part 202 - Technical Guidelines Regarding Sound Physical Condition

Code of Federal Regulations, 2010 CFR

2010-07-01

... Regarding Sound Physical Condition A Appendix A to Part 202 Patents, Trademarks, and Copyrights COPYRIGHT... COPYRIGHT Pt. 202, App. A Appendix A to Part 202—Technical Guidelines Regarding Sound Physical Condition To be considered a copy “of sound physical condition” within the meaning of 37 CFR 202.22(d)(5), a copy...

37 CFR Appendix A to Part 202 - Technical Guidelines Regarding Sound Physical Condition

Code of Federal Regulations, 2011 CFR

2011-07-01

... Regarding Sound Physical Condition A Appendix A to Part 202 Patents, Trademarks, and Copyrights COPYRIGHT... COPYRIGHT Pt. 202, App. A Appendix A to Part 202—Technical Guidelines Regarding Sound Physical Condition To be considered a copy “of sound physical condition” within the meaning of 37 CFR 202.22(d)(5), a copy...

Montana Standards and Guidelines for Career and Vocational/Technical Education. Summer 2002 Update.

ERIC Educational Resources Information Center

Montana State Office of Public Instruction, Helena.

This document presents Montana's standards and guidelines for career and vocational/technical education (CVTE). The guide begins with a directory of Montana's key CVTE personnel and specialists. Part 1 presents the federal and state definitions of CVTE and provides an overview of Montana's system for delivering CVTE and its philosophy regarding…

[Exploration of how to formulate guidelines on post-marketing traditional Chinese medicine surveillance].

PubMed

Zhang, Wen; Xie, Yan-Ming; Yu, Wen-Ya

2013-09-01

Combining the world health organization's (WHO), the United States and the European union's relevant laws and guidelines on post-marketing drug surveillance to judge the status of post-marketing surveillance of traditional Chinese medicine(TCM) in China. We found that due to the late start of post-marketing surveillance of traditional Chinese medicine, the appropriate guidelines are yet to be developed. Hence, hospitals, enterprises and research institutions do not have a shared foundation from which to compare their research results. Therefore there is an urgent need to formulate such post-marketing surveillance guidelines. This paper has used as guidance various technical documents such as, "procedures to formulate national standards" and "testing methods of management in formulating traditional Chinese medicine standards" and has combined these to produce a version of post-marketing surveillance particular to Chinese medicine in China. How to formulate these guidelines is discussed and procedures and methods to formulate technical specifications are introduced. These provide a reference for future technical specifications and will assist in the development of TCM.

RASSP Benchmark 4 Technical Description.

DTIC Science & Technology

1998-01-09

be carried out. Based on results of the study, an implementation of all, or part, of the system described in this benchmark technical description...validate interface and timing constraints. The ISA level of modeling defines the limit of detail expected in the VHDL virtual prototype. It does not...develop a set of candidate architectures and perform an architecture trade-off study. Candidate proces- sor implementations must then be examined for

COMP report: CPQR technical quality control guidelines for low-dose-rate permanent seed brachytherapy.

PubMed

Beaulieu, Luc; Radford, Dee-Ann; Eduardo Villarreal-Barajas, J

2018-03-14

The Canadian Organization of Medical Physicists (COMP), in close partnership with the Canadian Partnership for Quality Radiotherapy (CPQR) has developed a series of Technical Quality Control (TQC) guidelines for radiation treatment equipment. These guidelines outline the performance objectives that equipment should meet in order to ensure an acceptable level of radiation treatment quality. The TQC guidelines have been rigorously reviewed and field tested in a variety of Canadian radiation treatment facilities. The development process enables rapid review and update to keep the guidelines current with changes in technology. This article contains detailed performance objectives and safety criteria for low-dose-rate (LDR) permanent seed brachytherapy. © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

46 CFR Appendix B to Subpart C to... - Substance Technical Guidelines, Benzene

Code of Federal Regulations, 2010 CFR

2010-10-01

... Subpart C to Part 197—Substance Technical Guidelines, Benzene I. Physical and Chemical Data (a) Substance...: 71-43-2). (b) Physical data. (1) Boiling point (760 mm Hg): 80.1 °C (176 °F). (2) Specific gravity..., and Reactivity Hazard Data (a) Fire. (1) Flash point (closed cup): −11 °C (12 °F). (2) Autoignition...

37 CFR Appendix A to Part 202 - Technical Guidelines Regarding Sound Physical Condition

Code of Federal Regulations, 2014 CFR

2014-07-01

... Regarding Sound Physical Condition A Appendix A to Part 202 Patents, Trademarks, and Copyrights U.S... CLAIMS TO COPYRIGHT Pt. 202, App. A Appendix A to Part 202—Technical Guidelines Regarding Sound Physical Condition To be considered a copy “of sound physical condition” within the meaning of 37 CFR 202.22(d)(5), a...

KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors

PubMed Central

Lentine, Krista L.; Kasiske, Bertram L.; Levey, Andrew S.; Adams, Patricia L.; Alberú, Josefina; Bakr, Mohamed A.; Gallon, Lorenzo; Garvey, Catherine A.; Guleria, Sandeep; Li, Philip Kam-Tao; Segev, Dorry L.; Taler, Sandra J.; Tanabe, Kazunari; Wright, Linda; Zeier, Martin G.; Cheung, Michael; Garg, Amit X.

2017-01-01

Abstract The 2017 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors is intended to assist medical professionals who evaluate living kidney donor candidates and provide care before, during and after donation. The guideline development process followed the Grades of Recommendation Assessment, Development, and Evaluation (GRADE) approach and guideline recommendations are based on systematic reviews of relevant studies that included critical appraisal of the quality of the evidence and the strength of recommendations. However, many recommendations, for which there was no evidence or no systematic search for evidence was undertaken by the Evidence Review Team, were issued as ungraded expert opinion recommendations. The guideline work group concluded that a comprehensive approach to risk assessment should replace decisions based on assessments of single risk factors in isolation. Original data analyses were undertaken to produce a “proof-in-concept” risk-prediction model for kidney failure to support a framework for quantitative risk assessment in the donor candidate evaluation and defensible shared decision making. This framework is grounded in the simultaneous consideration of each candidate's profile of demographic and health characteristics. The processes and framework for the donor candidate evaluation are presented, along with recommendations for optimal care before, during, and after donation. Limitations of the evidence are discussed, especially regarding the lack of definitive prospective studies and clinical outcome trials. Suggestions for future research, including the need for continued refinement of long-term risk prediction and novel approaches to estimating donation-attributable risks, are also provided. In citing this document, the following format should be used: Kidney Disease: Improving Global Outcomes (KDIGO) Living Kidney Donor Work Group. KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors. Transplantation. 2017;101(Suppl 8S):S1–S109. PMID:28742762

The clinical development process for a novel preventive vaccine: An overview.

PubMed

Singh, K; Mehta, S

2016-01-01

Each novel vaccine candidate needs to be evaluated for safety, immunogenicity, and protective efficacy in humans before it is licensed for use. After initial safety evaluation in healthy adults, each vaccine candidate follows a unique development path. This article on clinical development gives an overview on the development path based on the expectations of various guidelines issued by the World Health Organization (WHO), the European Medicines Agency (EMA), and the United States Food and Drug Administration (USFDA). The manuscript describes the objectives, study populations, study designs, study site, and outcome(s) of each phase (Phase I-III) of a clinical trial. Examples from the clinical development of a malaria vaccine candidate, a rotavirus vaccine, and two vaccines approved for human papillomavirus (HPV) have also been discussed. The article also tabulates relevant guidelines, which can be referred to while drafting the development path of a novel vaccine candidate.

Outcomes of an Independent Review and Guidelines for the Implementation of a Program Review Model. Volume II. Technical Report.

ERIC Educational Resources Information Center

Carvell Education Managment Planning, Inc., Los Angeles, CA.

The second part of a report on a comprehensive review of the credit instructional programs offered by Pasadena City College (PCC), this volume contains a technical description of the data collection and assembly procedures used in the program review and provides guidelines for the implementation of the program review model. The first section…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anuar, Nuraslinda, E-mail: nuraslinda@uniten.edu.my; Kahar, Wan Shakirah Wan Abdul, E-mail: shakirah@tnb.com.my; Manan, Jamal Abdul Nasir Abd

Developing countries that are considering the deployment of nuclear power plants (NPPs) in the near future need to perform reactor technology assessment (RTA) in order to select the most suitable reactor design. The International Atomic Energy Agency (IAEA) reported in the Common User Considerations (CUC) document that “proven technology” is one of the most important technical criteria for newcomer countries in performing the RTA. The qualitative description of five desired features for “proven technology” is relatively broad and only provides a general guideline to its characterization. This paper proposes a methodology to define the “proven technology” term according to amore » specific country’s requirements using a three-stage evaluation process. The first evaluation stage screens the available technologies in the market against a predefined minimum Technology Readiness Level (TRL) derived as a condition based on national needs and policy objectives. The result is a list of technology options, which are then assessed in the second evaluation stage against quantitative definitions of CUC desired features for proven technology. The potential technology candidates produced from this evaluation is further narrowed down to obtain a list of proven technology candidates by assessing them against selected risk criteria and the established maximum allowable total score using a scoring matrix. The outcome of this methodology is the proven technology candidates selected using an accurate definition of “proven technology” that fulfills the policy objectives, national needs and risk, and country-specific CUC desired features of the country that performs this assessment. A simplified assessment for Malaysia is carried out to demonstrate and suggest the use of the proposed methodology. In this exercise, ABWR, AP1000, APR1400 and EPR designs assumed the top-ranks of proven technology candidates according to Malaysia’s definition of “proven technology”.« less

Unresolved Technical Issues in Fair Interest Measurement.

ERIC Educational Resources Information Center

Cole, Nancy S.

The problem of sex differences in interest measurement involves many technical issues and procedures. The purpose of this paper is to provide a description of the technical problems involved in construction, scoring, and interpretation of interest measures as related to sex differences and to suggest guidelines within these technical issues which…

Mixed strategies for energy conservation and alternative energy utilization (solar) in buildings. Final report. Volume II. Detailed results. [New York, Atlanta, Omaha, and Albuquerque

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1977-06-01

The mixed-strategy analysis was a tradeoff analysis between energy-conservation methods and an alternative energy source (solar) considering technical and economic benefits. The objective of the analysis was to develop guidelines for: reducing energy requirements; reducing conventional fuel use; and identifying economic alternatives for building owners. The analysis was done with a solar system in place. This makes the study unique in that it is determining the interaction of energy conservation with a solar system. The study, therefore, established guidelines as to how to minimize capital investment while reducing the conventional fuel consumption through either a larger solar system or anmore » energy-conserving technique. To focus the scope of energy-conservation techniques and alternative energy sources considered, five building types (house, apartment buildings, commercial buildings, schools, and office buildings) were selected. Finally, the lists of energy-conservation techniques and alternative energy sources were reduced to lists of manageable size by using technical attributes to select the best candidates for further study. The resultant energy-conservation techniques were described in detail and installed costs determined. The alternative energy source reduced to solar. Building construction characteristics were defined for each building for each of four geographic regions of the country. A mixed strategy consisting of an energy-conservation technique and solar heating/hot water/cooling system was analyzed, using computer simulation to determine the interaction between energy conservation and the solar system. Finally, using FEA fuel-price scenarios and installed costs for the solar system and energy conservation techniques, an economic analysis was performed to determine the cost effectiveness of the combination. (MCW)« less

Social Studies Teacher Candidates' Views on Historical Thinking Skills

ERIC Educational Resources Information Center

Ozmen, Cengiz

2015-01-01

Current study aimed to present Social Studies teacher candidates' views on historical thinking skills. Study was conducted using qualitative design and working group was composed of a total of 121 teacher candidates (62 females and 59 males) attending Social Studies Teaching Department of Karadeniz Technical University and Adiyaman University…

Development document for proposed effluent-limitations guidelines and standards for shipbuilding and repair. Point-source category

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1979-12-01

The document contains a discussion of the technical rationale for effluent limitations guidelines for the Shipbuilding and Repair Point Source Category, and the control and treatment technologies which form the basis for these guidelines.

Guidelines for the planning and preparation of illustrated technical talks

NASA Technical Reports Server (NTRS)

Hubbard, H. H.

1975-01-01

Guidelines are presented for the preparation of illustrated talks which are audience oriented and which are aimed at the efficient transfer of technical information. Early decisions concerning the required number of slides are helpful in initial planning for a good quality talk. Detailed considerations are: the establishment of limited objectives, selection of appropriate slide material, development of a text which is well coordinated with the slides, and accurate timing.

Pancreatic-duct-lavage cytology in candidates for surgical resection of branch-duct intraductal papillary mucinous neoplasm of the pancreas: should the International Consensus Guidelines be revised?

PubMed

Sai, Jin Kan; Suyama, Masafumi; Kubokawa, Yoshihiro; Watanabe, Sumio; Maehara, Tadayuki

2009-03-01

The International Consensus Guidelines are helpful for the management of branch-duct intraductal papillary mucinous neoplasms (IPMNs), because they allow us to exclude malignancy. However, it is not possible to predict malignancy with certainty, and further preoperative differentiation between benign and malignant IPMNs is required to avoid the false-positive results. To examine the usefulness of pancreatic-duct-lavage cytology by using an originally designed double-lumen catheter for discriminating benign and malignant IPMNs of the branch-duct type in candidates for surgical resection based on the International Consensus Guidelines. Pancreatic-duct-lavage cytology was investigated in 24 patients with branch-duct IPMNs who underwent surgical resection based on the International Consensus Guidelines, namely, they either had intramural nodules or the ectatic branch duct was >30 mm in diameter. Single-center retrospective study. Academic medical center. The sensitivity and specificity of pancreatic-duct-lavage cytology for discriminating benign from malignant IPMNs. More than 30 mL of pancreatic-duct-lavage fluid was obtained from each patient, and there were no patients with noninformative results. The sensitivity, specificity, positive predictive value, and negative predictive value of the cytologic diagnosis were 78%, 93%, 88%, and 88%, respectively. Single-center and small number of patients. Pancreatic-duct-lavage cytology can improve differentiation between benign and malignant IPMNs of the branch-duct type in candidates for surgical resection based on the International Consensus Guidelines.

7 CFR 3203.4 - Procedures.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE TRANSFER OF EXCESS COMPUTERS OR OTHER TECHNICAL EQUIPMENT..., in writing, an authorized official to approve transfers of excess computers or other technical...) Excess computers or other technical equipment must first be internally screened to ensure it is not...

7 CFR 3203.4 - Procedures.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE TRANSFER OF EXCESS COMPUTERS OR OTHER TECHNICAL EQUIPMENT..., in writing, an authorized official to approve transfers of excess computers or other technical...) Excess computers or other technical equipment must first be internally screened to ensure it is not...

Suborbital Safety Technical Committee- Summary of Proposed Standards & Guidelines

NASA Astrophysics Data System (ADS)

Quinn, Andy; Atencia Yepez, Amaya; Klicker, Michael; Howard, Diane; Verstraeten, Joram; Other Suborbital Safety TC Members

2013-09-01

There are currently no international safety standards and guidelines to assist designers, operators and authorities in the suborbital domain. There is a launch licensing regime in the United States (US) to assist the forerunners of the suborbital domain however this does not provide a safety approval for the vehicle against set standards or does not have an acceptable level of safety to achieve in terms of design or operation. In Europe a certification framework may be implemented however this (or any regulatory framework) is not in place as yet. This paper summarises the 5 tasks thus far completed by the International Association for the Advancement of Space Safety (IAASS) Suborbital Safety Technical Committee (SS TC) in terms of deriving standards and guidelines for the suborbital domain. The SS TC comprises members from the suborbital industry (US and European vehicle designers), safety experts, legal experts, medical/training experts, prospective spaceport operators and members from the US and European authorities (though these members cannot directly steer the standards and guidelines - they can merely review them for interest and comment on non-policy aspects). The SS TC has been divided into three working groups (WG): Regulatory WG, Technical WG and Operations WG. The 5 tasks that are summarised in this paper include: Regulatory WG - (Task 1) Clarify and promote regulatory framework for suborbital flights (including discussions on Space Law 'v' Air Law for suborbital domain); Technical WG - (Task 1) Defining & Alignment (globally) of Safety Criteria for Suborbital domain using industry best practices, (Task 2) Software/complex hardware certification for suborbital flights; Operations WG - (Task 1) Flight Crew and Spaceflight Participant Medical and Training Standards & Guidelines for suborbital flight, (Task 2) Spaceport Safety Management System. This paper also details the next set of standards and guidelines that will be derived by the SS TC. The paper concludes that these and future IAASS suborbital safety standards and guidelines are needed now and should beconsidered by the industry players before the first commercial flights expected late 2013/early 2014.

INTERNATIONAL ENGLISH MANUAL

DOE Office of Scientific and Technical Information (OSTI.GOV)

AMADOR, MABLE; KELLER, YVONNE KELLER

This document presents a set of guidelines for authors who wish to express themselves more clearly to foreign readers, or readers whose first language is not American English. Topics include idioms, technical terms, jargon, word meaning, acronyms, and international conventions of measurement. The guidelines will help writers of technical documents present their ideas more effectively to audiences that may include individuals whose first language is not American English, including audiences with individuals from other English-speaking countries.

Social Justice in Practice? Exploring Teacher Candidates' Commitment toward Change Agency through Action Research

ERIC Educational Resources Information Center

Burrell Storms, Stephanie

2015-01-01

Scholars have criticized teacher education programs for using action research (AR) to improve candidates' technical skills rather than promote its emancipatory goals. The author argues candidates who conduct critical AR promote its emancipatory goals and indicate a commitment to act as change agents for social justice through education. This…

STRATEGIES FOR EVALUATING INDICATORS BASED ON GUIDELINES FROM THE ENVIRONMENTAL PROTECTION AGENCY'S OFFICE OF RESEARCH AND DEVELOPMENT.

EPA Science Inventory

The Environmental Protection Agency's Office of Research and Development (ORD) has prepared technical guidelines to evaluate the suitability of ecological indicators for monitoring programs. The guidelines were adopted by ORD to provide a consistent framework for indicator review...

77 FR 20886 - Proposed Information Collection (Advertising, Sales, and Enrollment Materials, and Candidate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... information needed to ensure that educational institutions or agents enrollment materials meet VA's guidelines... information technology. Title: Advertising, Sales, and Enrollment Materials, and Candidate Handbooks, 38 CFR... collection. Abstract: VA approved educational institutions offering courses approved for the enrollment of...

PM Evaluation Guidelines.

ERIC Educational Resources Information Center

Bauch, Jerold P.

This paper presents guidelines for the evaluation of candidate performance, the basic function of the evaluation component of the Georgia program model for the preparation of elementary school teachers. The three steps in the evaluation procedure are outlined: (1) proficiency module (PM) entry appraisal (pretest); (2) self evaluation and the…

Student Services Program Planning and Evaluation: Responsibility, Procedures, Instrument, and Guidelines.

ERIC Educational Resources Information Center

Repp, Charles A.; Brach, Ronald C.

The manual provides a rationale, procedural guidelines, time-schedules, instruments, and supporting documentation for student services program evaluation at SUNY Agricultural and Technical College, Delhi. Six procedural guidelines include: (1) all programs and services should be evaluated at least once every four years, with provision for annual…

Preparing technical text for translation: A comparison between International English and methods for simplifying language

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buican, I.; Hriscu, V.; Amador, M.

For the past four and a half years, the International Communication Committee at Los Alamos National Laboratory has been working to develop a set of guidelines for writing technical and scientific documents in International English, that is, English for those whose native language is not English. Originally designed for documents intended for presentation in English to an international audience of technical experts, the International English guidelines apply equally well to the preparation of English text for translation. This is the second workshop in a series devoted to the topic of translation. The authors focus on the advantages of using Internationalmore » English, rather than various methods of simplifying language, to prepare scientific and technical text for translation.« less

Design Guidelines and Criteria for User/Operator Transactions with Battlefield Automated Systems. Volume I. Executive Summary

DTIC Science & Technology

1981-02-01

SUMMARY Robert N. Parrish, Jesse L. Gates, and Sarah J. Munger SYNECTICS CORPORATION HUMAN FACTORS TECHNICAL AREA L.. .iU. S. Army Research Institute for...of the Human Factors Technical Area, ARI, is the Contracting Officer’s Representative (COR) for this project. 19. KEY WORDS (Continue on reverse...aide It neceeary ad Identify by block number) Battlefield automated systems Human -computer interaction Design criteria System analysis Design guidelines

Summary Report: Risk Assessment Forum Technical Workshop on Population-level Ecological Risk Assessment

EPA Pesticide Factsheets

2008 technical workshop regarding development of additional guidelines or best practices for planning, implementing and interpreting ecological risk assessments that involve population-level assessment endpoints.

The examination assessment of technical competence in vascular surgery.

PubMed

Pandey, V A; Wolfe, J H N; Liapis, C D; Bergqvist, D

2006-09-01

The European Board of Surgery Qualification in Vascular Surgery is a pan-European examination for vascular surgeons who have attained a national certificate of completion of specialist training. A 2-year study was conducted before the introduction of a technical skills assessment in the examination. The study included 30 surgeons: 22 candidates and eight examiners. They were tested on dissection (on a synthetic saphenofemoral junction model), anastomosis (on to anterior tibial artery of a synthetic leg model) and dexterity (a knot-tying simulator with electromagnetic motion analysis). Validated rating scales were used by two independent examiners. Composite knot-tying scores were calculated for the computerized station. The stations were weighted 35, 45 and 20 percent, respectively. Examiners performed better than candidates in the dissection (P<0.001), anastomosis (P=0.002) and dexterity (P=0.005) stations. Participants performed consistently in the examination (dissection versus anastomosis: r=0.79, P<0.001; dexterity versus total operative score: r=-0.73, P<0.001). Interobserver reliability was high (alpha=0.91). No correlation was seen between a candidate's technical skill and oral examination performance or logbook-accredited scores. Current surgical examinations do not address technical competence. This model appears to be a valid assessment of technical skills in an examination setting. The standards are set at a level appropriate for a specialist vascular surgeon. Copyright (c) 2006 British Journal of Surgery Society Ltd.

Facilitating Grade Acceleration: Revisiting the Wisdom of John Feldhusen

ERIC Educational Resources Information Center

Culross, Rita R.; Jolly, Jennifer L.; Winkler, Daniel

2013-01-01

This article revisits the 1986 Feldhusen, Proctor, and Black recommendations on grade skipping. These recommendations originally appeared as 12 guidelines. In this article, the guidelines are grouped into three general categories: how to screen accelerant candidates, how to engage with the adults in the acceleration process (e.g., teachers,…

Guidelines for the conversion of urban four-lane undivided roadways to three-lane two-way left-turn lane facilities

DOT National Transportation Integrated Search

2001-04-01

The primary objective of this research project was to develop a set of guidelines to assist in the selection of candidate roadways for urban four-lane undivided to three-lane cross section conversions. The authors evaluated and assessed the physical,...

10 CFR 960.3-2-2-1 - Evaluation of all potentially acceptable sites.

Code of Federal Regulations, 2013 CFR

2013-01-01

...-1 Section 960.3-2-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-1 Evaluation... technical guidelines of subparts C and D, in accordance with the application requirements set forth in...

10 CFR 960.3-2-2-1 - Evaluation of all potentially acceptable sites.

Code of Federal Regulations, 2012 CFR

2012-01-01

...-1 Section 960.3-2-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-1 Evaluation... technical guidelines of subparts C and D, in accordance with the application requirements set forth in...

10 CFR 960.3-2-2-1 - Evaluation of all potentially acceptable sites.

Code of Federal Regulations, 2011 CFR

2011-01-01

...-1 Section 960.3-2-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-1 Evaluation... technical guidelines of subparts C and D, in accordance with the application requirements set forth in...

10 CFR 960.3-2-1 - Site screening for potentially acceptable sites.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Section 960.3-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-1 Site screening for... technical guidelines can exist in the same land unit, the DOE shall seek to evaluate the composite...

10 CFR 960.3-2-1 - Site screening for potentially acceptable sites.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Section 960.3-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-1 Site screening for... technical guidelines can exist in the same land unit, the DOE shall seek to evaluate the composite...

10 CFR 960.3-2-1 - Site screening for potentially acceptable sites.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Section 960.3-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-1 Site screening for... technical guidelines can exist in the same land unit, the DOE shall seek to evaluate the composite...

10 CFR 960.3-2-2-1 - Evaluation of all potentially acceptable sites.

Code of Federal Regulations, 2014 CFR

2014-01-01

...-1 Section 960.3-2-2-1 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-1 Evaluation... technical guidelines of subparts C and D, in accordance with the application requirements set forth in...

Guidelines for the effective operation and control of VDOT permanent variable message sign and highway advisory radio units : state of the practice and recommendations : technical assistance report.

DOT National Transportation Integrated Search

1996-01-01

On January 31, 1996, VDOT's Statewide Incident Management (SIM) Committee requested that guidelines for the control of permanent variable message sign (VMS) and permanent highway advisory radio (HAR) units be developed. The guidelines do not address ...

ADAAG Review Federal Advisory Committee Recommendations for a New ADAAG. Final Report.

ERIC Educational Resources Information Center

Architectural and Transportation Barriers Compliance Board, Washington, DC.

This report presents the final recommendations, in the form of a new set of guidelines, of a federal advisory committee concerning revisions to the Americans with Disabilities Act Accessibility Guidelines (ADAAG). The guidelines provide scoping and technical requirements for the design, construction, and alteration of sites, facilities, buildings,…

Development of protocols to inventory or monitor wildlife, fish, or rare plants

Treesearch

David Vesely; Brenda C. McComb; Christina D. Vojta; Lowell H. Suring; Jurai Halaj; Richard S. Holthausen; Benjamin Zuckerberg; Patricia M. Manley

2006-01-01

The purpose of this technical guide (hereafter referred to as the Species Protocol Technical Guide) is to provide guidelines for developing inventory and monitoring (I&M) protocols for wildlife, fish, and rare plants (WFRP) using the U.S. Department of Agriculture (USDA) Forest Service technical guide format.

Evaluating Technical Communication Faculty: Some Empirically-Based Criteria and Guidelines. Draft.

ERIC Educational Resources Information Center

Stevenson, Dwight W.

As technical communication is a young academic discipline, evaluating technical communication faculty for promotion, tenure, and merit purposes requires special awareness and care. To determine reasonable expectations of faculty achievement, a study documented the range, types, and frequency of activities of 12 professors and 12 associate…

48 CFR 1816.402-270 - NASA technical performance incentives.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA technical performance incentives. 1816.402-270 Section 1816.402-270 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND....402-270 NASA technical performance incentives. (a) Pursuant to the guidelines in 1816.402, NASA has...

48 CFR 1816.402-270 - NASA technical performance incentives.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA technical performance incentives. 1816.402-270 Section 1816.402-270 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND....402-270 NASA technical performance incentives. (a) Pursuant to the guidelines in 1816.402, NASA has...

48 CFR 1816.402-270 - NASA technical performance incentives.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA technical performance incentives. 1816.402-270 Section 1816.402-270 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND....402-270 NASA technical performance incentives. (a) Pursuant to the guidelines in 1816.402, NASA has...

48 CFR 1816.402-270 - NASA technical performance incentives.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA technical performance incentives. 1816.402-270 Section 1816.402-270 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND....402-270 NASA technical performance incentives. (a) Pursuant to the guidelines in 1816.402, NASA has...

48 CFR 1816.402-270 - NASA technical performance incentives.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA technical performance incentives. 1816.402-270 Section 1816.402-270 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND....402-270 NASA technical performance incentives. (a) Pursuant to the guidelines in 1816.402, NASA has...

36 CFR Appendix D to Part 1191 - Technical

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Technical D Appendix D to Part 1191 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE...; ARCHITECTURAL BARRIERS ACT (ABA) ACCESSIBILITY GUIDELINES Pt. 1191, App. D Appendix D to Part 1191—Technical...

Advanced Public Transportation Systems. Technical Assistance Brief 2

DOT National Transportation Integrated Search

1993-01-01

The Advanced Public Transportation Systems (APTS) Program requires evaluation : of pilot projects. This technical assistance brief discusses the guidelines set : for developing evaluation framework and methodology for local projects. 4p.

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... conform to the technical specifications, including file requirements, described in the Federal Election Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal... outstanding campaign obligations. (b) Organization of computerized information and technical specifications...

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... conform to the technical specifications, including file requirements, described in the Federal Election Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal... outstanding campaign obligations. (b) Organization of computerized information and technical specifications...

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... conform to the technical specifications, including file requirements, described in the Federal Election Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal... outstanding campaign obligations. (b) Organization of computerized information and technical specifications...

Evolution of Toxoplasma-PCR methods and practices: a French national survey and proposal for technical guidelines.

PubMed

Roux, Guillaume; Varlet-Marie, Emmanuelle; Bastien, Patrick; Sterkers, Yvon

2018-06-08

The molecular diagnosis of toxoplasmosis lacks standardisation due to the use of numerous methods with variable performance. This diversity of methods also impairs robust performance comparisons between laboratories. The harmonisation of practices by diffusion of technical guidelines is a useful way to improve these performances. The knowledge of methods and practices used for this molecular diagnosis is an essential step to provide guidelines for Toxoplasma-PCR. In the present study, we aimed (i) to describe the methods and practices of Toxoplasma-PCR used by clinical microbiology laboratories in France and (ii) to propose technical guidelines to improve molecular diagnosis of toxoplasmosis. To do so, a yearly self-administered questionnaire-based survey was undertaken in proficient French laboratories from 2008 to 2015, and guidelines were proposed based on the results of those as well as previously published work. This period saw the progressive abandonment of conventional PCR methods, of Toxoplasma-PCR targeting the B1 gene and of the use of two concomitant molecular methods for this diagnosis. The diversity of practices persisted during the study, in spite of the increasing use of commercial kits such as PCR kits, DNA extraction controls and PCR inhibition controls. We also observed a tendency towards the automation of DNA extraction. The evolution of practices did not always go together with an improvement in those, as reported notably by the declining use of Uracil-DNA Glycosylase to avoid carry-over contamination. We here propose technical recommendations which correspond to items explored during the survey, with respect to DNA extraction, Toxoplasma-PCR and good PCR practices. Copyright © 2018 Australian Society for Parasitology. Published by Elsevier Ltd. All rights reserved.

National Health Guidelines in I.R of Iran, an Innovative Approach for Developing Countries

PubMed Central

Esmaeil Akbari, Mohammad; Mohammadi, Gohar; Vosoogh-Moghaddam, Abbas; Rabanikhah, Fahimeh; Javadi, Hamideh; Rostami-Gooran, Narges; Safaei, Asal; Akbari, Atieh

2015-01-01

Background Guidelines have produced and used in complex environment of health care system with its ethical, economical, legal and other aspects; that should be taken into account in any country. Modifying the format and content of guidelines might facilitate their usage and lead to improved quality of care and cost containment. We have produced this tool for explained above purpose. Methods A coordinating national team has settled at the office of minster of health and medical education, supported by a guideline review committee. An innovative and appropriate approach for adapting national health guidelines has consisted of eight steps, have defined For preparing the draft of each guideline a technical team which, including main author, her/his co-workers have nominated. The authors of each topic have systematically searched databases of the proposed Twenty-two International Sites, and then have selected at least five sources of them that were more relevant. The final recommendations have proposed by agreement of technical team and Guideline Review Committee. Results In less than 5 months, more than 500 authors in whole country have selected to prepare guidelines and, approximately 150 guidelines have provided in three volumes of the published and distributed book. Each guideline had a national ID number, constant forever; all topics should be reviewed every 3-5 years. Conclusion National health guideline(s) would be essential means for policy making in health system and increased the cost containment and quality of care. Ministry of Health and Medical Education should provide and distribute the guidelines based on its accountability to legal responsibility. PMID:25960845

National health guidelines in I.R of iran, an innovative approach for developing countries.

PubMed

Esmaeil Akbari, Mohammad; Mohammadi, Gohar; Vosoogh-Moghaddam, Abbas; Rabanikhah, Fahimeh; Javadi, Hamideh; Rostami-Gooran, Narges; Safaei, Asal; Akbari, Atieh

2015-01-01

Guidelines have produced and used in complex environment of health care system with its ethical, economical, legal and other aspects; that should be taken into account in any country. Modifying the format and content of guidelines might facilitate their usage and lead to improved quality of care and cost containment. We have produced this tool for explained above purpose. A coordinating national team has settled at the office of minster of health and medical education, supported by a guideline review committee. An innovative and appropriate approach for adapting national health guidelines has consisted of eight steps, have defined For preparing the draft of each guideline a technical team which, including main author, her/his co-workers have nominated. The authors of each topic have systematically searched databases of the proposed Twenty-two International Sites, and then have selected at least five sources of them that were more relevant. The final recommendations have proposed by agreement of technical team and Guideline Review Committee. In less than 5 months, more than 500 authors in whole country have selected to prepare guidelines and, approximately 150 guidelines have provided in three volumes of the published and distributed book. Each guideline had a national ID number, constant forever; all topics should be reviewed every 3-5 years. National health guideline(s) would be essential means for policy making in health system and increased the cost containment and quality of care. Ministry of Health and Medical Education should provide and distribute the guidelines based on its accountability to legal responsibility.

ASEAN GMP and pharmaceutical industries in Indonesia.

PubMed

Soesilo, S; Sitorus, U

1995-01-01

Indonesia was appointed by the ASEAN Technical Cooperation in Pharmaceutical as a focal point and to coordinate the development of practical guidelines for the implementation of GMP. The ASEAN GMP Guidelines were endorsed by the ASEAN Technical Cooperation in Pharmaceutical in 1988, which among others required separation of Beta-Lactam dedicated facilities and three degrees of cleanliness for production areas. As it was realised that drug manufacturers in developing countries need more detailed guidelines to be able to implement the GMP, an Operational Manual for GMP was also prepared for providing examples of SOPs lay-outs, documentation etc. It was agreed by the technical cooperation group to leave the implementation of GMP to each member country. However, the ASEAN Manual for Inspection of GMP was drafted and endorsed by the group and training of ASEAN Drug Inspectors was organized to support the implementation. The ASEAN GMP is being implemented in Indonesia through a five-year, stepwise implementation plan, starting in 1989.

Should living kidney donor candidates with impaired fasting glucose donate?

PubMed

Vigneault, Christine Buchek; Asch, William Stuart; Dahl, Neera Kanhouwa; Bia, Margaret Johnson

2011-08-01

As the kidney transplant waiting list grows, the willingness of transplant centers to accept complex donors increases. Guidelines for the evaluation of living kidney donors exist but do not provide clear guidance when evaluating the complex donor. Although few transplant centers will approve donor candidates with impaired glucose tolerance and most, if not all, will deny candidates with diabetes, many will approve candidates with impaired fasting glucose (IFG). Furthermore, the demographic of living donors has changed in the past 10 years to increasingly include more nonwhite and Hispanic individuals who are at greater risk for future diabetes and hypertension. IFG may be more of a concern in potential donors whose nonwhite and Hispanic ethnicity already places them at greater risk. We review the definition of diabetes, diabetes prediction tools, and transplant guidelines for donor screening and exclusion as it pertains to impaired glucose metabolism, and additional ethnic and nonethnic factors to consider. We offer an algorithm to aid in evaluation of potential living donors with IFG in which ethnicity, age, and features of the metabolic syndrome play a role in the decision making.

TECHNICAL GUIDANCE DOCUMENT: THE FABRICATION OF POLYETHYLENE FML FIELD SEAMS

EPA Science Inventory

This technical guidance document is meant to augment the numerous construction quality control and construction assurance (CQC and CQA) guidelines that are presently available for high density polyethylene (HDPE) liner installation and inspection.

Instructor/Operator Station Design Handbook for Aircrew Training Devices. Final Technical Report for Period March 1982-December 1986.

ERIC Educational Resources Information Center

Warner, H. D.

Human engineering guidelines for the design of instructor/operator stations (IOSs) for aircrew training devices are provided in this handbook. These guidelines specify the preferred configuration of IOS equipment across the range of the anticipated user sizes and performance capabilities. The guidelines are consolidated from various human…

Solar Energy - It's Growth, Development, and Use

Science.gov Websites

Report, June 1978 Solar Energy and Your Home: Questions and Answers, DOE Technical Report, January 1984 Solar Air Collectors: How Much Can You Save?, DOE Technical Report, April 1985 Building Design Guidelines for Solar Energy Technologies, DOE Technical Report, January 1989 OUT Success Stories: Solar

Multiparametric magnetic resonance imaging and prostate cancer: what's new?

PubMed

Catalá, V; Vilanova, J C; Gaya, J M; Algaba, F; Martí, T

Prostatic multi-parametric magnetic resonance imaging (MP-MRI) has recently had a wide development becoming a key tool in the diagnostic and therapeutic decisions in prostate cancer (Pca). The fast development both in technology and in reading (PIRADS V2) requires a continuous updating of knowledge within this area. The aim of this article is to present an updated revision of technical aspects, reading patterns and prostatic MP-MRI in Pca, with a multidisciplinary approach. Currently guidelines establish the use of the MP-MRI when there is a high PSA and a negative prostatic biopsy; tumor staging; evaluation in candidates to active surveillance; focal treatments plans and tumoral recurrence evaluation. Although it is used in other indications in some centers, like its use in patients suspicious of Pca but with no previous biopsy, there is still the need of a cost/benefit assessment for its use to be wider. Copyright © 2017 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved.

A practical guide to epidemiological practice and standards in the identification and validation of diagnostic markers using a bladder cancer example.

PubMed

Behrens, T; Bonberg, N; Casjens, S; Pesch, B; Brüning, T

2014-01-01

Technical advances to analyze biological markers have generated a plethora of promising new marker candidates for early detection of cancer. However, in subsequent analyses only few could be successfully validated as being predictive, clinically useful, or effective. This failure is partially due to rapid publication of results that were detected in early stages of biomarker research. Methodological considerations are a major concern when carrying out molecular epidemiological studies of diagnostic markers to avoid errors that increase the potential for bias. Although guidelines for conducting studies and reporting of results have been published to improve the quality of marker studies, their planning and execution still need to be improved. We will discuss different sources of bias in study design, handling of specimens, and statistical analysis to illustrate possible pitfalls associated with marker research, and present legal, ethical, and technical considerations associated with storage and handling of specimens. This article presents a guide to epidemiological standards in marker research using bladder cancer as an example. Because of the possibility to detect early cancer stages due to leakage of molecular markers from the target organ or exfoliation of tumor cells into the urine, bladder cancer is particularly useful to study diagnostic markers. To improve the overall quality of marker research, future developments should focus on networks of studies and tissue banks according to uniform legal, ethical, methodological, and technical standards. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. © 2013.

Standardization by ISO to Ensure the Sustainability of Space Activities

NASA Astrophysics Data System (ADS)

Kato, A.; Lazare, B.; Oltrogge, D.; Stokes, H.

2013-08-01

The ISO / Technical Committee 20 / Sub-committee 14 develops debris-related standards and technical reports to mitigate debris and help ensure mission and space sustainability. While UN Guidelines and the IADC Guidelines encourage national governments and agencies to promote debris mitigation design and operation, the ISO standards will help the global space industry promote and sustain its space-related business. In this paper the scope and status of each ISO standard is discussed within an overall framework. A comparison with international guidelines is also provided to demonstrate the level of consistency. Finally, as a case study, the ISO standards are applied to a CubeSat mission, thus demonstrating their usability on a relatively recent and popular class of satellite.

CRITICAL EVALUATION OF ECOLOGICAL INDICATORS

EPA Science Inventory

EPA's Office of Research and Development (ORD) has prepared fifteen technical guidelines to evaluate the suitability of an ecological indicator in a monitoring program. The guidelines were fashioned to provide a consistent framework for indicator review and to provide guidance fo...

77 FR 26660 - Guidelines for the Transfer of Excess Computers or Other Technical Equipment Pursuant to Section...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

....usda.gov . SUPPLEMENTARY INFORMATION: A. Background A proposed rule was published in the Federal.... Computers or other technical equipment means central processing units, laptops, desktops, computer mouses...

Technical evaluation of RETS-required reports for Browns Ferry Nuclear Power Station, Units 1, 2, and 3, for 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Young, T.E.; Magleby, E.H.

1985-09-06

A review was performed of reports required by federal regulations and the plant-specific radiological effluent technical specifications (RETS) for operations conducted at Tennessee Valley Authority's Browns Ferry Nuclear Station, Units 1, 2, and 3, during 1983. The two periodic reports reviewed were (a) the Effluents and Waste Disposal Semiannual Report, First Half 1983 and (b) the Effluents and Waste Disposal Semiannual Report, Second Half 1983. The principal review guidelines were the plant's specific RETs and NRC guidance given in NUREG-0133, ''Preparation of Radiological Effluent Technical Specifications for Nuclear Power Plants.'' The Licensee's submitted reports were found to be reasonably completemore » and consistent with the review guidelines.« less

Causal fermion systems as a candidate for a unified physical theory

NASA Astrophysics Data System (ADS)

Finster, Felix; Kleiner, Johannes

2015-07-01

The theory of causal fermion systems is an approach to describe fundamental physics. Giving quantum mechanics, general relativity and quantum field theory as limiting cases, it is a candidate for a unified physical theory. We here give a non-technical introduction.

Guidelines for Creating and Using Abbreviations and Acronyms

NASA Technical Reports Server (NTRS)

Miller, Diane F.

1995-01-01

The unchecked use of acronyms and initialisms in technical writing presents a huge obstacle to clarity and readability. Although technical communicators are certainly more aware of this problem than are the engineers, scientists, and managers with whom they work, they need concrete guidelines and at least a small degree of self-righteousness on this subject to help them cope with the onslaught. That acronyms frustrate communication is well founded in linguistic theory, not to mention common sense. Suggestions for mitigating their destructiveness include issues of audience, term selectivity, frequency and occasion of use, and aesthetics.

Recipient selection process and listing for lung transplantation

PubMed Central

Dupont, Lieven; Yserbyt, Jonas; Schaevers, Veronique; Van Raemdonck, Dirk; Neyrinck, Arne; Vos, Robin

2017-01-01

Lung transplantation remains the ultimate treatment option for selected patients with end-stage (cardio) pulmonary disease. Given the current organ shortage, it is without any doubt that careful selection of potential transplant candidates is essential as this may greatly influence survival after the procedure. In this paper, we will review the current guidelines for referral and listing of lung transplant candidates in general, and in more depth for the specific underlying diseases. Needless to state that these are not absolute guidelines, and that decisions depend upon center’s activity, waiting list, etc. Therefore, every patient should be discussed with the transplant center before any definite decision is made to accept or decline a patient for lung transplantation. PMID:29221322

Designing and Building Integrated Digital Library Systems: Guidelines. IFLA Professional Reports, No. 90

ERIC Educational Resources Information Center

Rathje, Bente Dahl; McGrory, Margaret; Pollitt, Carol; Voutilainen, Paivi

2005-01-01

The purpose of these Guidelines is to provide libraries for the blind and those who work in them with a broad overview of matters to be considered in planning and implementing an integrated digital library system. The Guidelines are not intended to provide technical solutions. Given the pace of technological change, solutions can only be developed…

[Technical guideline for human rabies prevention and control (2016)].

PubMed

Zhou, H; Li, Y; Chen, R F; Tao, X Y; Yu, P C; Cao, S C; Li, L; Chen, Z H; Zhu, W Y; Yin, W W; Li, Y H; Wang, C L; Yu, H J

2016-02-01

In order to promote the prevention and control programs on rabies in our country, to regulate the prevention and disposition of rabies and to reduce the deaths caused by rabies, the Chinese Center for Disease Control and Prevention has organized a panel of experts, in the reference with Guidelines issued by WHO, American Advisory Committee on Immunization Practices, and the latest research progress from home and abroad, and compiled this document-"Technical Guidelines for Human Rabies Prevention and Control (2016)". The Guidelines conducted a systematic review on the etiology, clinical characteristics, laboratory diagnosis, epidemiology of rabies and provided evidence on varieties, mechanisms, effects, side-effects and security of rabies vaccine, as well as on other preparations on passive immunity of its kind, on methods related to prevention and disposition of exposure etc, finally to have come up with the recommendation on the above mentioned various techniques. The guidelines will be used by staff working on prevention and control of rabies from the Center for Disease Control and Prevention at all levels, from the departments of outpatient and divisions of infection and emergency control in all the medical institutions. The guideline will be updated and revised, following the research progress from home and abroad.

Workplace Health and Safety across the Vocational/Technical Curriculum.

ERIC Educational Resources Information Center

Ryan, Thomas; Hinkley, Carl

This document contains the outcomes of a pilot project to develop materials and methods of integrating occupational health and safety into the curriculum of the technologies at a technical college. Section I is a model of how to integrate health and safety into a vocational-technical curriculum. Based on the Outcomes-Based Guidelines developed by…

Collection Assessment. SPEC Kit 41.

ERIC Educational Resources Information Center

Association of Research Libraries, Washington, DC. Office of Management Studies.

This Association of Research Libraries (ARL) kit on collection assessment contains the following documents: (1) "Guidelines for the Evaluation of Library Collections--Draft Copy" (Collection Development Committee, Resource Section, Resources and Technical Services Division, American Library Association); (2) "Guidelines for Collection Assessment"…

Selection of Valid Reference Genes for Reverse Transcription Quantitative PCR Analysis in Heliconius numata (Lepidoptera: Nymphalidae)

PubMed Central

Chouteau, Mathieu; Whibley, Annabel; Joron, Mathieu; Llaurens, Violaine

2016-01-01

Identifying the genetic basis of adaptive variation is challenging in non-model organisms and quantitative real time PCR. is a useful tool for validating predictions regarding the expression of candidate genes. However, comparing expression levels in different conditions requires rigorous experimental design and statistical analyses. Here, we focused on the neotropical passion-vine butterflies Heliconius, non-model species studied in evolutionary biology for their adaptive variation in wing color patterns involved in mimicry and in the signaling of their toxicity to predators. We aimed at selecting stable reference genes to be used for normalization of gene expression data in RT-qPCR analyses from developing wing discs according to the minimal guidelines described in Minimum Information for publication of Quantitative Real-Time PCR Experiments (MIQE). To design internal RT-qPCR controls, we studied the stability of expression of nine candidate reference genes (actin, annexin, eF1α, FK506BP, PolyABP, PolyUBQ, RpL3, RPS3A, and tubulin) at two developmental stages (prepupal and pupal) using three widely used programs (GeNorm, NormFinder and BestKeeper). Results showed that, despite differences in statistical methods, genes RpL3, eF1α, polyABP, and annexin were stably expressed in wing discs in late larval and pupal stages of Heliconius numata. This combination of genes may be used as a reference for a reliable study of differential expression in wings for instance for genes involved in important phenotypic variation, such as wing color pattern variation. Through this example, we provide general useful technical recommendations as well as relevant statistical strategies for evolutionary biologists aiming to identify candidate-genes involved adaptive variation in non-model organisms. PMID:27271971

Guidelines for producing training films and videos.

PubMed

Harper, P B

1991-01-01

Drawing from experience in producing a film on the surgical procedure of female sterilization, 4 guidelines to technical film production for training purposes are presented and discussed in this paper. In order of presentation in the text, the paper 1st encourages identifying and securing a technical expert, then clearly identifying steps of the technical procedure, involving trainees and trainers in the production process, and working with experienced producers, scriptwriters, and crew members. Returning to the 1st guideline, the technical advisor will have a central presence during all photography and editing, and ideally should not have any personal investment in the procedure being shown. Prior to script finalization and sorting, research is urged to ensure concrete procedural steps. Printed materials, slides, interviews of experienced clinicians, procedure observation, and test videotape shooting may be called upon and employed as parts of the research phase. Trainees should participate during preliminary research, script development, and pretesting of early film versions, their suggestions for change incorporated where appropriate in the final version. On the final point of securing experienced workers, country nationals sensitive to relevant cultural and background dynamics should be included in the team. The special concerns of airport security regulation and customs requirements knowledge are essential, as well as their attention to assuring adequate on-site electricity for camera equipment.

Guidelines for Sampling, Assessing, and Restoring Defective Grout in Prestressed Concrete Bridge Post-Tensioning Ducts

DOT National Transportation Integrated Search

2013-05-01

This document is a technical summary of the Federal Highway Administration report, "Guidelines for Sampling, Assessing, and Restoring Defective Grout in Prestressed Concrete Bridge Post-Tensioning Ducts" (FHWA-HRT-13-028). The objectives of this stud...

Technical Review Board Chairperson Guidelines for Conducting Technical Review Boards for Rocket Testing

DTIC Science & Technology

2011-08-17

to create a guide for technical review board chairperson conducting technical review boards for rocket testing performed by the Air Force Research ...BOARDS FOR ROCKET TESTING   TABLE OF CONTENTS List of Acronyms 1 Abstract 2 Chapter 1. Introduction 3 Introduction and Research Question 3...boards for rocket testing performed by the Air Force Research Laboratory’s Space Missile Propulsion Division located at Edwards Air Force Base in

78 FR 46331 - Biomass Research and Development Technical Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-31

... DEPARTMENT OF ENERGY Biomass Research and Development Technical Advisory Committee AGENCY: Energy... Energy is soliciting nominations for candidates to fill vacancies on the Biomass Research and Development... INFORMATION: The Biomass Research and Development Act of 2000 (Biomass Act) [Pub. L. 106-224] requires...

Validation of biomarkers of food intake-critical assessment of candidate biomarkers.

PubMed

Dragsted, L O; Gao, Q; Scalbert, A; Vergères, G; Kolehmainen, M; Manach, C; Brennan, L; Afman, L A; Wishart, D S; Andres Lacueva, C; Garcia-Aloy, M; Verhagen, H; Feskens, E J M; Praticò, G

2018-01-01

Biomarkers of food intake (BFIs) are a promising tool for limiting misclassification in nutrition research where more subjective dietary assessment instruments are used. They may also be used to assess compliance to dietary guidelines or to a dietary intervention. Biomarkers therefore hold promise for direct and objective measurement of food intake. However, the number of comprehensively validated biomarkers of food intake is limited to just a few. Many new candidate biomarkers emerge from metabolic profiling studies and from advances in food chemistry. Furthermore, candidate food intake biomarkers may also be identified based on extensive literature reviews such as described in the guidelines for Biomarker of Food Intake Reviews (BFIRev). To systematically and critically assess the validity of candidate biomarkers of food intake, it is necessary to outline and streamline an optimal and reproducible validation process. A consensus-based procedure was used to provide and evaluate a set of the most important criteria for systematic validation of BFIs. As a result, a validation procedure was developed including eight criteria, plausibility, dose-response, time-response, robustness, reliability, stability, analytical performance, and inter-laboratory reproducibility. The validation has a dual purpose: (1) to estimate the current level of validation of candidate biomarkers of food intake based on an objective and systematic approach and (2) to pinpoint which additional studies are needed to provide full validation of each candidate biomarker of food intake. This position paper on biomarker of food intake validation outlines the second step of the BFIRev procedure but may also be used as such for validation of new candidate biomarkers identified, e.g., in food metabolomic studies.

Pre-Employment Testing on the Internet: Put Candidates a Click Away and Hire at Modem Speed.

ERIC Educational Resources Information Center

Mooney, John

2002-01-01

The experience of a county government illustrates factors to consider in implementing online employment testing for job candidates: (1) selection of the appropriate Internet-based test; (2) passwords, timing, security, and technical difficulties; and (3) provisions for applicants who lack Internet access. (SK)

USSR Report, Political and Sociological Affairs, Press Surveys from Soviet Southern Republics

DTIC Science & Technology

1984-02-10

candidate in art history, on "The Theater of Socialist Realism and the Spiritual-Esthetic Education of Youth" and by N. Mehdiev, candidate in...Procurator; Court; Internal Affairs Office; Main Office of People’s Education; Offices of Health, Vocational-Technical Education, Culture, Cinematization and

Looking at Learning as Preparation for Teaching

ERIC Educational Resources Information Center

Hughes-McDonnell, Fiona J.

2016-01-01

One of the more heated and consequential debates in teacher education today concerns the instructional methods used in preparation programs and the knowledge and skills that teacher candidates should acquire. In this study, I examine looking at learning as a pedagogical approach to transition teacher candidates from the technical conceptions of…

Distance Learning for Teacher Education. Report of a Technical Working Group Meeting (Islamabad, Pakistan, 4-16 November 1981). Volume II: Guidelines on Development of Materials.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and the Pacific.

This handbook, the second volume in a series of three publications on distance education, presents guidelines on structures and strategies in organizations and the processes of materials development. A checklist of specific items is included for each topic addressed. The first guidelines are addressed to policymakers and senior administrators and…

Ergonomic guidelines for using notebook personal computers. Technical Committee on Human-Computer Interaction, International Ergonomics Association.

PubMed

Saito, S; Piccoli, B; Smith, M J; Sotoyama, M; Sweitzer, G; Villanueva, M B; Yoshitake, R

2000-10-01

In the 1980's, the visual display terminal (VDT) was introduced in workplaces of many countries. Soon thereafter, an upsurge in reported cases of related health problems, such as musculoskeletal disorders and eyestrain, was seen. Recently, the flat panel display or notebook personal computer (PC) became the most remarkable feature in modern workplaces with VDTs and even in homes. A proactive approach must be taken to avert foreseeable ergonomic and occupational health problems from the use of this new technology. Because of its distinct physical and optical characteristics, the ergonomic requirements for notebook PCs in terms of machine layout, workstation design, lighting conditions, among others, should be different from the CRT-based computers. The Japan Ergonomics Society (JES) technical committee came up with a set of guidelines for notebook PC use following exploratory discussions that dwelt on its ergonomic aspects. To keep in stride with this development, the Technical Committee on Human-Computer Interaction under the auspices of the International Ergonomics Association worked towards the international issuance of the guidelines. This paper unveils the result of this collaborative effort.

NASA Publications Guide for Authors. Revised

NASA Technical Reports Server (NTRS)

2005-01-01

This document presents guidelines for use by NASA authors for preparing and publishing their scientific and technical information (STI). Section 1 gives an overview. Section 2 describes each type of report in the NASA STI Report Series and other forms of publications. It also discusses dissemination and safeguarding of STI. Section 3 gives technical, data quality, and dissemination reviews, including the mandatory review via NASA Form 1676, NASA Scientific and Technical Information (STI) Document Availability Authorization (DAA). It also describes handling unlimited and limited/restricted STI. Section 4 provides recommended standards for document format, composition, and organization and element of a typical report. Section 5 presents miscellaneous preparation recommendations. Section 6 discusses two required forms, Standard Form 298 and NF-1676. The guide cites additional sources of information of standards, guidelines, and review and approval requirements.

An Assessment of Technical and Production Risks of Candidate Low-Cost Attitude/Heading Reference Systems(AHRS)

NASA Technical Reports Server (NTRS)

Yuchnovicz, Daniel; Burgess, Malcolm; Hammers, William

1999-01-01

This report provides an assessment of technical and production risks of candidate low-cost attitude/heading reference systems (AHRS) for use in the Advanced General Aviation Transport Experiments (AGATE) airplanes. A low-cost AHRS is a key component of modem "glass cockpit" flight displays for General Aviation (GA) aircraft. The technical capabilities of several candidate low-cost AHRS were examined and described along with the technical issues involved with using all solid-state components for attitude measurement. An economic model was developed which describes the expected profit, rate of return, and volume requirements for the manufacture of low-cost AHRS for GA aircraft in the 2000 to 2020 time frame. The model is the result of interviews with GA airframe manufacturers, avionics manufacturers and historical analysis of avionics of similar complexity. The model shows that a manufacturer will break even after three years of AHRS production, realizing an 18 percent rate of return (23 percent profit) on an investment of $3.5M over the 20 year period. A start-up production estimate showed costs of $6-12M for a new company to build and certify an AHRS from scratch, considered to be a high-risk proposition, versus $0.25-0.75M for an experienced avionics manufacturer to manufacture a design under license, a low-risk proposition.

16 CFR 1115.26 - Guidelines and policies.

Code of Federal Regulations, 2014 CFR

2014-01-01

... SUBSTANTIAL PRODUCT HAZARD REPORTS Guidelines and Requirements for Mandatory Recall Notices § 1115.26... minimize the use of highly technical or legal terminology. (3) A recall notice should be targeted and...; (ii) Computer, radio, television, or other electronic transmission or medium; (iii) Video news release...

16 CFR 1115.26 - Guidelines and policies.

Code of Federal Regulations, 2012 CFR

2012-01-01

... SUBSTANTIAL PRODUCT HAZARD REPORTS Guidelines and Requirements for Mandatory Recall Notices § 1115.26... minimize the use of highly technical or legal terminology. (3) A recall notice should be targeted and...; (ii) Computer, radio, television, or other electronic transmission or medium; (iii) Video news release...

7 CFR 3203.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... described in paragraph (1) of this definition. Computers or other technical equipment means central... 7 Agriculture 15 2013-01-01 2013-01-01 false Definitions. 3203.3 Section 3203.3 Agriculture..., DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE TRANSFER OF EXCESS COMPUTERS OR OTHER TECHNICAL EQUIPMENT...

Effects of an electronic reminder system on guideline-concordant treatment of psychotic disorders : Results from a pilot feasibility trial.

PubMed

Franke, Irina; Thier, Sarah; Riecher-Rössler, Anita

2016-12-01

Adherence to evidence-based guidelines is essential for the treatment outcome of psychotic disorders. Previous studies showed that IT-supported pathways are able to increase guideline adherence in psychiatric care. This paper describes a pilot study on the development of an electronic recall-reminder-system (RRS) for supporting guideline-adherent treatment in outpatient care of patients with chronic psychotic disorders and analyses its feasibility. Guidelines were integrated in the RRS software M.E.M.O.R.E.S. Software training for the staff was provided. We compared the number of conducted vs. guideline-recommended interventions 6 months before and after implementation. Subsequently both the caregivers' and the patients' satisfaction with the RRS was evaluated. Guideline adherence in general was low and the RRS was barely used. After its implementation a significant increase was observed in chemogram-check-ups and diagnostics regarding cardiovascular risks (esp. ECG). Both patients and professionals described problems with integrating the RRS in their daily routine and questioned the usefulness of the guidelines for chronically ill, although they basically approved its importance and usefulness. Participants appreciated the idea of supporting guideline adherence with an IT-system, but there seemed to be major obstacles to implementation: caregivers appear to be concerned of being exposed or questioned, technical difficulties might lead to avoidance, and there seems to be a lack of knowledge and awareness about the health risks for individuals with psychotic disorders. Possibly guidelines adapted for the chronically ill would find more acceptance. Technical simplifications and better information should be considered prior to further attempts to implement IT-supported guidelines in order to increase acceptance.

Guidelines for developing or supplementing natural photo series.

Treesearch

Wayne G. Maxwell; Franklin Ward

1980-01-01

These guidelines provide the land manager with procedures for making local supplements to General Technical Report PNW-105, "Photo Series for Quantifying Natural Forest Residues in Common Vegetation Types of the Pacific Northwest"; the process used to photograph and measure residues and summarize the data is described.

GUIDELINES FOR THE BIOREMEDIATION OF OIL-CONTAMINATED SALT MARSHES

EPA Science Inventory

The objective of this document is to present a detailed technical guideline for use by spill responders for the cleanup of coastal wetlands contaminated with oil and oil products by using one of the least intrusive approaches
bioremediation technology. This manual is a supplem...

16 CFR § 1115.26 - Guidelines and policies.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REGULATIONS SUBSTANTIAL PRODUCT HAZARD REPORTS Guidelines and Requirements for Mandatory Recall Notices § 1115... minimize the use of highly technical or legal terminology. (3) A recall notice should be targeted and...; (ii) Computer, radio, television, or other electronic transmission or medium; (iii) Video news release...

The fate of technical-grade chlordane in mice fed a high-fat diet and its roles as a candidate obesogen.

PubMed

Wang, Dezhen; Wang, Xinru; Zhang, Ping; Wang, Yao; Zhang, Renke; Yan, Jin; Zhou, Zhiqiang; Zhu, Wentao

2017-03-01

Epidemiological studies indicate that exposure to persistent organic pollutants is positively associated with the prevalence of obesity. To delineate the potential role of technical-grade chlordane in obesity development, chlordane metabolism and chlordane-induced metabolic changes were investigated in mice fed high-fat diet (HFD) over a 6-week period. Gas chromatography-electron capture detector analysis showed that HFD induced more accumulation of technical chlordane in the liver, muscle and adipose tissue. The enantioselectivities of oxychlordane in selected tissues were also influenced by HFD. 1 H NMR-based liver metabolome indicated that technical chlordane can enhance the metabolic alterations induced by HFD. Compared with the low-fat diet (LFD) group, no differences were observed in the LFD + chlordane group. However, as many as 16 metabolites were significantly different between the HFD group and HFD + chlordane group. Moreover, compared to the LFD + chlordane group, the abundances of 24 metabolites significantly increased or decreased in the HFD + chlordane group. Twenty metabolites were altered in the HFD group compared to the LFD group. Tryptophan profiling suggested that both chlordane and HFD can disturb tryptophan catabolism. These interactions between technical chlordane and HFD suggest that technical chlordane is a candidate obesogen. Copyright © 2016 Elsevier Ltd. All rights reserved.

Physical Screening Predictors for Success in Completing Air Force Phase II Air Liaison Officer Aptitude Assessment.

PubMed

McGee, John Christopher; Wilson, Eric; Barela, Haley; Blum, Sharon

2017-03-01

Air Liaison Officer Aptitude Assessment (AAA) attrition is often associated with a lack of candidate physical preparation. The Functional Movement Screen, Tactical Fitness Assessment, and fitness metrics were collected (n = 29 candidates) to determine what physical factors could predict a candidate s success in completing AAA. Between-group comparisons were made between candidates completing AAA versus those who did not (p < 0.05). Upper 50% thresholds were established for all variables with R 2 < 0.8 and the data were converted to a binary form (0 = did not attain threshold, 1 = attained threshold). Odds-ratios, pre/post-test probabilities and positive likelihood ratios were computed and logistic regression applied to explain model variance. The following variables provided the most predictive value for AAA completion: Pull-ups (p = 0.01), Sit-ups (p = 0.002), Relative Powerball Toss (p = 0.017), and Pull-ups × Sit-ups interaction (p = 0.016). Minimum recommended guidelines for AAA screening are Pull-ups (10 maximum), Sit-ups (76/2 minutes), and a Relative Powerball Toss of 0.6980 ft × lb/BW. Associated benefits could be higher graduation rates, and a cost-savings associated from temporary duty and possible injury care for nonselected candidates. Recommended guidelines should be validated in future class cycles. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

Study of space shuttle EVA/IVA support requirements. Volume 2: EVA/IVA tasks, guidelines, and constraints definition

NASA Technical Reports Server (NTRS)

Webbon, B. W.; Copeland, R. J.; Wood, P. W., Jr.; Cox, R. L.

1973-01-01

The guidelines for EVA and IVA tasks to be performed on the space shuttle are defined. In deriving tasks, guidelines, and constraints, payloads were first identified from the mission model. Payload requirements, together with man and manipulator capabilities, vehicle characteristics and operation, and safety considerations led to a definition of candidate tasks. Guidelines and constraints were also established from these considerations. Scenarios were established, and screening criteria, such as commonality of EVA and IVA activities, were applied to derive representative planned and unplanned tasks. The whole spectrum of credible contingency situations with a potential requirement for EVA/IVA was analyzed.

Critical Thinking Tendencies of Geography Teacher Candidates in Turkey

ERIC Educational Resources Information Center

Geçit, Yilmaz; Akarsu, Ali Haydar

2017-01-01

The purpose of this research is to determine the critical thinking levels of geography teacher candidates. The research was descriptive and conducted in a relational survey model. The population of this study consists of students of the geography department of Karadeniz Technical University, Atatürk University and Marmara University education…

[Digital electroencephalography in brain death diagnostics : Technical requirements and results of a survey on the compatibility with medical guidelines of digital EEG systems from providers in Germany].

PubMed

Walter, U; Noachtar, S; Hinrichs, H

2018-02-01

The guidelines of the German Medical Association and the German Society for Clinical Neurophysiology and Functional Imaging (DGKN) require a high procedural and technical standard for electroencephalography (EEG) as an ancillary method for diagnosing the irreversible cessation of brain function (brain death). Nowadays, digital EEG systems are increasingly being applied in hospitals. So far it is unclear to what extent the digital EEG systems currently marketed in Germany meet the guidelines for diagnosing brain death. In the present article, the technical und safety-related requirements for digital EEG systems and the EEG documentation for diagnosing brain death are described in detail. On behalf of the DGKN, the authors sent out a questionnaire to all identified distributors of digital EEG systems in Germany with respect to the following technical demands: repeated recording of the calibration signals during an ongoing EEG recording, repeated recording of all electrode impedances during an ongoing EEG recording, assessability of intrasystem noise and galvanic isolation of measurement earthing from earthing conductor (floating input). For 15 of the identified 20 different digital EEG systems the specifications were provided by the distributors (among them all distributors based in Germany). All of these EEG systems are provided with a galvanic isolation (floating input). The internal noise can be tested with all systems; however, some systems do not allow repeated recording of the calibration signals and/or the electrode impedances during an ongoing EEG recording. The majority but not all of the currently available digital EEG systems offered for clinical use are eligible for use in brain death diagnostics as per German guidelines.

10 CFR 300.13 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 3 2012-01-01 2012-01-01 false Incorporation by reference. 300.13 Section 300.13 Energy DEPARTMENT OF ENERGY CLIMATE CHANGE VOLUNTARY GREENHOUSE GAS REPORTING PROGRAM: GENERAL GUIDELINES § 300.13 Incorporation by reference. The Technical Guidelines for the Voluntary Reporting of Greenhouse Gases (1605(b...

10 CFR 300.13 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 3 2013-01-01 2013-01-01 false Incorporation by reference. 300.13 Section 300.13 Energy DEPARTMENT OF ENERGY CLIMATE CHANGE VOLUNTARY GREENHOUSE GAS REPORTING PROGRAM: GENERAL GUIDELINES § 300.13 Incorporation by reference. The Technical Guidelines for the Voluntary Reporting of Greenhouse Gases (1605(b...

10 CFR 300.13 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 3 2014-01-01 2014-01-01 false Incorporation by reference. 300.13 Section 300.13 Energy DEPARTMENT OF ENERGY CLIMATE CHANGE VOLUNTARY GREENHOUSE GAS REPORTING PROGRAM: GENERAL GUIDELINES § 300.13 Incorporation by reference. The Technical Guidelines for the Voluntary Reporting of Greenhouse Gases (1605(b...

10 CFR 300.13 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Incorporation by reference. 300.13 Section 300.13 Energy DEPARTMENT OF ENERGY CLIMATE CHANGE VOLUNTARY GREENHOUSE GAS REPORTING PROGRAM: GENERAL GUIDELINES § 300.13 Incorporation by reference. The Technical Guidelines for the Voluntary Reporting of Greenhouse Gases (1605(b...

10 CFR Appendix III to Part 960 - Application of the System and Technical Guidelines During the Siting Process

Code of Federal Regulations, 2011 CFR

2011-01-01

... presents a table that specifies how the guidelines of subparts C and D are to be applied at certain... Characteristics ......do 3 5-2-9(d) ......do Disqualifying 1 5-2-10(a) Hydrology Qualifying 3 5-2-10(d) ......do...

10 CFR 300.13 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Incorporation by reference. 300.13 Section 300.13 Energy DEPARTMENT OF ENERGY CLIMATE CHANGE VOLUNTARY GREENHOUSE GAS REPORTING PROGRAM: GENERAL GUIDELINES § 300.13 Incorporation by reference. The Technical Guidelines for the Voluntary Reporting of Greenhouse Gases (1605(b...

A Rationale for Criterion-Referenced Proficiency Testing

ERIC Educational Resources Information Center

Clifford, Ray

2016-01-01

This article summarizes some of the technical issues that add to the complexity of language testing. It focuses in particular on the criterion-referenced nature of the ACTFL Proficiency Guidelines-Speaking; and it proposes a criterion-referenced interpretation of the ACTFL guidelines for reading and listening. It then demonstrates how using…

Case Studies - Creating a Digital Marketspace Presence: Lessons in Extranet Implementation.

ERIC Educational Resources Information Center

Angeles, Rebecca

2001-01-01

This study seeks a practical understanding of the business, organizational, and technical components of and implementation guidelines needed to effectively deploy extranets. It aims to establish a basic conceptual framework for understanding extranet implementation guidelines. Provides a specific case using VF Playwear, Inc.'s HealthTexbtob.com, a…

Measure Guideline. Deep Energy Enclosure Retrofit for Interior Insulation of Masonry Walls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Musunuru, S.; Pettit, B.

2015-04-30

This Measure Guideline describes a deep energy enclosure retrofit solution for insulating mass masonry buildings from the interior. It describes the retrofit assembly, technical details, and installation sequence for retrofitting masonry walls. Interior insulation of masonry retrofits might adversely affect the durability of the wall. This guideline includes a review of decision criteria pertinent to retrofitting masonry walls from the interior and the possible risk of freeze-thaw damage.

76 FR 32202 - Science Advisory Board Staff Office Request for Additional Nominations for the SAB Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-03

... Additional Nominations for the SAB Environmental Justice Technical Review Panel(s) AGENCY: Environmental...) which consider environmental justice concerns. DATES: Nominations should be submitted by June 24, 2011... justice technical documents. The SAB is now seeking to augment the list of potential candidates to include...

Considerations on the Improved Integration of Medical Guidelines into Routine Clinical Practice – a Review and Concept Proposal

PubMed Central

Beckmann, M. W.; Schlieter, H.; Richter, P.; Wesselmann, S.

2016-01-01

Medical guidelines have become established as the standard for the comprehensive synopsis of all available information (scientific trials, expert opinion) on diagnosis and treatment recommendations. The transfer of guidelines to clinical practice and subsequent monitoring has however proven difficult. In particular the potential interaction between guideline developers and guideline users has not been fully utilised. This review article analyses the status quo and existing methodological and technical information solutions supporting the guideline life cycle. It is shown that there are numerous innovative developments that in isolation do not provide comprehensive support. The vision of the “Living Guidelines 2.0” is therefore presented. This outlines the merging of guideline development and implementation on the basis of clinical pathways and guideline-based quality control, and building on this, the generation of information for guideline development and research. PMID:27134291

System installation package for the New Hampshire Vocational Technical College, Manchester, N. H.

NASA Technical Reports Server (NTRS)

1979-01-01

A system installed in the residential solar laboratory located at the New Hampshire Vocational Technical College in Manchester, N. H. is described. General guidelines which may be utilized in development of detailed installation plans and specifications, as well as instructions on operation and maintenance are provided.

Healthy Water Healthy People Field Monitoring Guide

ERIC Educational Resources Information Center

Project WET Foundation, 2003

2003-01-01

This 100-page manual serves as a technical reference for the "Healthy Water, Healthy People Water Quality Educators Guide" and the "Healthy Water Healthy People Testing Kits". Yielding in-depth information about ten water quality parameters, it answers questions about water quality testing using technical overviews, data interpretation guidelines,…

Analysis of Additive Manufacturing for Sustainment of Naval Aviation Systems

DTIC Science & Technology

2017-09-01

selection methodology to query the aviation spare-parts inventory for identification of additive manufacturing candidates. The methodology organizes...a component selection methodology to query the aviation spare-parts inventory for identification of additive manufacturing candidates. The... methodology organizes the resultant data using a top-down approach that aligns technical feasibility with programmatic objectives. Finally, a discrete event

Teacher Candidates' Attitudes to Using Oral History in History Education

ERIC Educational Resources Information Center

Demircioglu, Ebru

2016-01-01

The aim of this research is to determine the views of history teacher candidates towards an oral history project carried out in the Special Teaching Method Course of the history pedagogy program of the Fatih Faculty of Education (FFE) at Karadeniz Technical University in Turkey. An open-ended questionnaire and semi-structured interview were the…

[Medical habilitation in German-speaking countries : Quantitative assessment of content and elaboration of habilitation guidelines].

PubMed

Weineck, S B; Koelblinger, D; Kiesslich, T

2015-04-01

Habilitation defines the qualification to conduct self-contained university teaching and is the key for access to a professorship at German, Austrian and Swiss universities. Despite all changes implemented in the European higher education systems during the Bologna process, it is the highest qualification level issued through the process of an university examination and remains the core concept of scientific careers in these countries. In the field of medicine, this applies not only to scientific staff at the universities but also to those medical doctors aiming at a clinical career track. To provide a quantitative analysis of the scientific, didactic, and procedural criteria for medical habilitation in German-speaking countries. Based on the guidelines of all 43 medical academic institutions, the criteria which candidates are required to fulfil prior to habilitation as well as formal requirements related to the habilitation procedure itself have been acquired and quantitatively analyzed. Having evaluated all habilitation guidelines by means of 87 items, the quantitative analysis revealed significant differences in terms of number, kind and scale of criteria stated therein. Most habilitation guidelines scarcely define the capabilities applicants have to prove: concerning the scientific qualifications on types of publications for instance, no item was mentioned in more than half of all habilitation guidelines. Based on this data analysis, the authors discuss the related literature and describe five main distinguishing areas of habilitation guidelines in terms of the set of the formal and procedural framework as well as the prequalification and postqualification criteria imposed on habilitation candidates. There are therefore substantial differences in the organization of the habilitation for medicine.

Telling about the analyst's pregnancy.

PubMed

Uyehara, L A; Austrian, S; Upton, L G; Warner, R H; Williamson, R A

1995-01-01

Pregnancy is one of several events in the life of an analyst which may affect an analysis, calling for special technical considerations. For the analyst, this exception to the tenet of anonymity, along with countertransference guilt, narcissistic preoccupation, heightened infantile conflicts, and intense patient responses, may stimulate anxiety that becomes focused on the timing and manner of informing the patient. For the patient, preoccupation with the timing of the telling may serve as a displacement from other meanings of the pregnancy. Candidate analysts may face particular difficulties managing the impact of their pregnancies on control cases. We address practical and technical considerations in telling, the transference and counter-transference surrounding it, ethical concerns, and the challenges of supervising a pregnant candidate.

Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 2: Technical analysis

NASA Technical Reports Server (NTRS)

1978-01-01

A technical analysis on the feasibility of commercial manufacturing of pharmaceuticals in space is presented. The method of obtaining pharmaceutical company involvement, laboratory results of the separation of serum proteins by the continuous flow electrophoresis process, the selection and study of candidate products, and their production requirements is described. The candidate products are antihemophilic factor, beta cells, erythropoietin, epidermal growth factor, alpha-1-antitrypsin and interferon. Production mass balances for antihemophelic factor, beta cells, and erythropoietin were compared for space versus ground operation. A conceptual description of a multiproduct processing system for space operation is discussed. Production requirements for epidermal growth factor of alpha-1-antitrypsin and interferon are presented.

Guidelines for Controlling Indoor Air Quality Problems Associated with Kilns, Copiers, and Welding in Schools. Technical Bulletin.

ERIC Educational Resources Information Center

Turner, Ronald W.; And Others

Guidelines for controlling indoor air quality problems associated with kilns, copiers, and welding in schools are provided in this document. Individual sections on kilns, duplicating equipment, and welding operations contain information on the following: sources of contaminants; health effects; methods of control; ventilation strategies; and…

Virginia Erosion and Sediment Control Handbook. Standards, Criteria and Guidelines.

ERIC Educational Resources Information Center

Virginia State Soil and Water Conservation Commission, Richmond, VA.

Guidelines and technical standards for development of local erosion and sediment control programs and conservation standards to meet the goals established by the Virginia Erosion and Sediment Control law are presented in this handbook. Part I defines natural and manmade erosion, sedimentation, and the hazards of uncontrolled wear and damage to the…

THE U.S. EPA NATIONAL HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH LABORATORY'S APPROACH TO AUDITING HEALTH EFFECTS STUDIES

EPA Science Inventory

This is an abstract of a proposed presentation and does not necessarily reflect EPA policy.

The Health Divisions of the US EPA National Health and Environmental Effects Research Laboratory have a guideline for conducting technical systems audits. As part of the guideline ...

Technical Guidelines for Digital Learning Content: Development, Evaluation, Selection, Acquisition and Use

ERIC Educational Resources Information Center

Southern Regional Education Board (SREB), 2005

2005-01-01

The Educational Technology Cooperative of the Southern Regional Education Board (SREB) established the Digital Learning Content initiative to identify guidelines and develop recommendations to assist those who develop, evaluate, select, acquire and use digital learning content to create products that are easy to access and use in order to ensure…

DEVELOPMENT AND AVAILABILITY OF EQUILIBRIUM PARTITIONING SEDIMENT GUIDELINES (ESGS) FOR NONIONIC ORGANIC CONTAMINANTS, METALS MIXTURES, AND POLYCYCLIC AROMATIC HYDROCARBON (PAH) MIXTURES

EPA Science Inventory

Collaborative efforts between EPA's Office of Water and Office of Research and Development have resulted in the development of sediment guidelines based on equilibrium partitioning theory (EqP). The guidance available includes a technical support document, describing the derivat...

Solar Energy Task Force Report: Technical Training Guidelines.

ERIC Educational Resources Information Center

O'Connor, Kevin

This task force report offers guidelines and information for the development of vocational education programs oriented to the commercial application of solar energy in water and space heating. After Section I introduces the Solar Energy Task Force and its activities, Section II outlines the task force's objectives and raises several issues and…

Congenital rubella syndrome surveillance in Honduras.

PubMed

Molina, Ida Berenice; Mendoza, Lourdes Otilia; Palma, María Aparicia

2011-09-01

Congenital rubella syndrome (CRS) surveillance was established in Honduras to determine the scope of the problem and assess the impact of vaccination. Implementation of the surveillance system required the drafting of national CRS epidemiological surveillance guidelines, the development of a laboratory diagnostic method, and training of physicians, nurses, and microbiologists in the Honduran hospital network and social security system on CRS surveillance guidelines. Honduras' experience with the surveillance of other vaccine-preventable diseases facilitated the implementation of hospital-based CRS surveillance. The surveillance system operates in 23 of the 25 public hospitals that offer services to children and at 2 social security hospitals; the private sector has not been integrated into this system. Clinical and technical staff, including representatives from various disciplines such as pediatrics, neonatology, general medicine, epidemiology, nursing, and microbiology, participate in the hospital network, as well as follow up on cases in accordance with the standardized guidelines, depending on their areas of expertise. Implementation of the CRS surveillance system requires technical guidelines, laboratory diagnostic capacity, and trained multidisciplinary human resources for its systematization and operation.

Characterizing Phage Genomes for Therapeutic Applications

PubMed Central

Philipson, Casandra W.; Voegtly, Logan J.; Lueder, Matthew R.; Long, Kyle A.; Rice, Gregory K.; Frey, Kenneth G.; Biswas, Biswajit; Cer, Regina Z.; Hamilton, Theron; Bishop-Lilly, Kimberly A.

2018-01-01

Multi-drug resistance is increasing at alarming rates. The efficacy of phage therapy, treating bacterial infections with bacteriophages alone or in combination with traditional antibiotics, has been demonstrated in emergency cases in the United States and in other countries, however remains to be approved for wide-spread use in the US. One limiting factor is a lack of guidelines for assessing the genomic safety of phage candidates. We present the phage characterization workflow used by our team to generate data for submitting phages to the Federal Drug Administration (FDA) for authorized use. Essential analysis checkpoints and warnings are detailed for obtaining high-quality genomes, excluding undesirable candidates, rigorously assessing a phage genome for safety and evaluating sequencing contamination. This workflow has been developed in accordance with community standards for high-throughput sequencing of viral genomes as well as principles for ideal phages used for therapy. The feasibility and utility of the pipeline is demonstrated on two new phage genomes that meet all safety criteria. We propose these guidelines as a minimum standard for phages being submitted to the FDA for review as investigational new drug candidates. PMID:29642590

Get your science used—Six guidelines to improve your products

USGS Publications Warehouse

Perry, Suzanne C.; Blanpied, Michael L.; Burkett, Erin R.; Campbell, Nnenia M.; Carlson, Anders; Cox, Dale A.; Driedger, Carolyn L.; Eisenman, David P.; Fox-Glassman, Katherine T.; Hoffman, Sherry; Hoffman, Susanna M.; Jaiswal, Kishor S.; Jones, Lucile M.; Luco, Nicolas; Marx, Sabine M.; McGowan, Sean M.; Mileti, Dennis S.; Moschetti, Morgan P.; Ozman, David; Pastor, Elizabeth; Petersen, Mark D.; Porter, Keith A.; Ramsey, David W.; Ritchie, Liesel A.; Fitzpatrick, Jessica K.; Rukstales, Kenneth S.; Sellnow, Timothy L.; Vaughon, Wendy L.; Wald, David J.; Wald, Lisa A.; Wein, Anne; Zarcadoolas, Christina

2016-03-03

On the basis of research and practice into how people think, use tools, make decisions, and understand scientific/technical information, the social and behavioral scientists, marketers, and social-impact designers at the NSHM workshop provided remarkably consistent guidelines to develop successful science products, such as text, maps, and other products. In this report the guidelines are numbered for clarity, but they can be applied repeatedly, piecemeal, or out of order to fit each project and your resources.

[Des-interest in professional educating in the production of the National Seminar on Guidelines for Nursing Education].

PubMed

Vieira, Silvana Lima; da Silva, Gilberto Tadeu Reis; Fernandes, Josicelia Dumêt; e Silva, Ana Cláudia de Azevêdo Bião; Santana, Monique Santos; Santos, Thadeu Borges Souza

2014-01-01

Documentary, retrospective, quali-quantitative research, which aimed to examine the approaches of scientific productions through summaries of the 12 and 13 national seminar on guidelines for the education in nursing, which raised the medium-level technical professional education in nursing. quantify and discuss the scientific production of events regarding the geographical distribution of authors, objectives and methodology of the studies. As a criterion for inclusion the abstracts should contain at least one of the following descriptors in the title and/or objectives: education in nursing, technical education in nursing, vocational education. Reviewed 637 abstracts, 23 met the inclusion criteria. The production was concentrated in the Southeast region in Brazil and the objectives featured mainly teaching practices of the nurses. There was little expressiveness of vocational at the event, signaling the need for more studies, considering the relevance of the technical level professionals for the Nursing profession and the health system.

Protocol for Atomic Oxygen Testing of Materials in Ground-Based Facilities. No. 2

NASA Technical Reports Server (NTRS)

Minton, Timothy K.

1995-01-01

A second version of standard guidelines is proposed for improving materials testing in ground-based atomic oxygen environments for the purpose of predicting the durability of the tested materials in low Earth orbit (LEO). Accompanying these guidelines are background information and notes about testing. Both the guidelines and the additional information are intended to aid users who wish to evaluate the potential hazard of atomic oxygen in LEO to a candidate space component without actually flying the component in space, and to provide a framework for more consistent atomic oxygen testing in the future.

Industrial Arts Curriculum Guide in Basic Technical Drafting. Bulletin No. 1686.

ERIC Educational Resources Information Center

Louisiana State Dept. of Education, Baton Rouge. Div. of Vocational Education.

This curriculum guide contains operational guidelines to help local administrators, teacher educators, and industrial arts teachers in the State of Louisiana determine the extent to which their technical drafting courses are meeting the needs of the youth they serve. It consists of a discussion of course prerequisites, goals, content, and…

Financing Options for Home Care for Children with Chronic Illness and Severe Disability. Technical Assistance Manual.

ERIC Educational Resources Information Center

Ellison, Marsha Langer; And Others

This manual is intended to accompany technical assistance efforts aimed at improving selected states' home health care programs for children with chronic illness and severe disability. Summary descriptions of funding sources are presented, including purpose, eligibility guidelines, and services covered, as well as additional information as…

Fox Valley Technical College Quality First Process Model.

ERIC Educational Resources Information Center

Fox Valley Technical Coll., Appleton, WI.

An overview is provided of the Quality First Process Model developed by Fox Valley Technical College (FVTC), Wisconsin, to provide guidelines for quality instruction and service consistent with the highest educational standards. The 16-step model involves activities that should be adaptable to any organization. The steps of the quality model are…

"A Technical Assistance Report" on Computer Technology Applications. Smithville School District, Smithville, Massachusetts.

ERIC Educational Resources Information Center

Merrimack Education Center, Chelmsford, MA.

This report of the Technical Assistance Study provided to the Smithville Public Schools by the Technology Lighthouse of the Merrimack Education Center offers information for use in planning computer technology applications over a 3-year period. It provides specific guidelines and criteria for planning and development, equipment considerations,…

10 CFR 960.3-1-1 - Diversity of geohydrologic settings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-1 Diversity of geohydrologic... development of repositories may be located. To the extent practicable, sites recommended as candidate sites...

Occupational Safety and Health in Vocational Education: A Guide for Administrators, Faculty, and Staff.

ERIC Educational Resources Information Center

Godbey, Frank W.

This guide is intended to help administrators at schools having vocational education programs assess their occupational safety and health needs and establish a program to ensure a safer and more healthful work environment. It consists of three sections: (1) administrative guidelines, (2) technical-regulatory guidelines, and (3) a self-evaluation…

Environmentally Sound Small-Scale Livestock Projects. Guidelines for Planning Series Number 5.

ERIC Educational Resources Information Center

Jacobs, Linda

This document was developed in response to the need for simplified technical information for planning environmentally sound small-scale projects in third world countries. It is aimed specifically at those who are planning or managing small-scale livestock projects in less-developed areas of the tropics and sub-tropics. The guidelines included in…

Predictive validity of a selection centre testing non-technical skills for recruitment to training in anaesthesia.

PubMed

Gale, T C E; Roberts, M J; Sice, P J; Langton, J A; Patterson, F C; Carr, A S; Anderson, I R; Lam, W H; Davies, P R F

2010-11-01

Assessment centres are an accepted method of recruitment in industry and are gaining popularity within medicine. We describe the development and validation of a selection centre for recruitment to speciality training in anaesthesia based on an assessment centre model incorporating the rating of candidate's non-technical skills. Expert consensus identified non-technical skills suitable for assessment at the point of selection. Four stations-structured interview, portfolio review, presentation, and simulation-were developed, the latter two being realistic scenarios of work-related tasks. Evaluation of the selection centre focused on applicant and assessor feedback ratings, inter-rater agreement, and internal consistency reliability coefficients. Predictive validity was sought via correlations of selection centre scores with subsequent workplace-based ratings of appointed trainees. Two hundred and twenty-four candidates were assessed over two consecutive annual recruitment rounds; 68 were appointed and followed up during training. Candidates and assessors demonstrated strong approval of the selection centre with more than 70% of ratings 'good' or 'excellent'. Mean inter-rater agreement coefficients ranged from 0.62 to 0.77 and internal consistency reliability of the selection centre score was high (Cronbach's α=0.88-0.91). The overall selection centre score was a good predictor of workplace performance during the first year of appointment. An assessment centre model based on the rating of non-technical skills can produce a reliable and valid selection tool for recruitment to speciality training in anaesthesia. Early results on predictive validity are encouraging and justify further development and evaluation.

Conceptual Design of a Space-Based Multimegawatt MHD Power System, Task 1 Topical Report; Volume 1: Technical Discussion

DTIC Science & Technology

1988-01-01

system requirements, design guidelines, and interface requirements has been prepared and included as Volume II of this Task 1 topical report. The Volume ...WAESD-TR-88-0002 Conceptual Design Of A Space-Based Multimegawatt MHD Power System ffA«kjjjjjTfc Task 1 Topical Report Volume I: Technical...Space-Based Multimegawatt MHD Power System: Task 1 Topical Report, Volume I: Technical Discussion Personal Author: Dana, RA. Corporate Author Or

DEMONSTRATION OF FUEL CELLS TO RECOVER ENERGY FROM LANDFILL GAS - PHASE III. DEMONSTRATION TESTS - PHASE IV. GUIDELINES AND RECOMMENDATIONS- VOLUME 1. TECHNICAL REPORT

EPA Science Inventory

The report summarizes the results of a four-phase program to demonstrate that fuel cell energy recovery using a commercial phosphoric acid fuel cell is both environmentally sound and commercially feasible. Phase I, a conceptual design and evaluation study, addressed the technical...

NASA Publications Guide for Authors

NASA Technical Reports Server (NTRS)

2015-01-01

This document presents guidelines for use by NASA authors in preparation and publication of their scientific and technical information (STI). Section 2 gives an overview. Section 2 describes types of publication. Section 3 discusses technical, data/information, and dissemination reviews. Section 4 provides recommended standards and gives the elements of a typical report. Section 5 presents miscellaneous preparation recommendations.

Improving the Basic Skills of Vocational-Technical Students: An Administrator's Guide. Competency-Based Vocational Education Administrator Module Series.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This guide provides information and guidelines intended to assist vocational administrators in developing and evaluating programs to improve the basic skills of vocational-technical students. Part one provides background information about basic skills and examines their role in vocational education. Discussed next are various program types,…

Clinical Practice Guideline: Improving Nasal Form and Function after Rhinoplasty.

PubMed

Ishii, Lisa E; Tollefson, Travis T; Basura, Gregory J; Rosenfeld, Richard M; Abramson, Peter J; Chaiet, Scott R; Davis, Kara S; Doghramji, Karl; Farrior, Edward H; Finestone, Sandra A; Ishman, Stacey L; Murphy, Robert X; Park, John G; Setzen, Michael; Strike, Deborah J; Walsh, Sandra A; Warner, Jeremy P; Nnacheta, Lorraine C

2017-02-01

Objective Rhinoplasty, a surgical procedure that alters the shape or appearance of the nose while preserving or enhancing the nasal airway, ranks among the most commonly performed cosmetic procedures in the United States, with >200,000 procedures reported in 2014. While it is difficult to calculate the exact economic burden incurred by rhinoplasty patients following surgery with or without complications, the average rhinoplasty procedure typically exceeds $4000. The costs incurred due to complications, infections, or revision surgery may include the cost of long-term antibiotics, hospitalization, or lost revenue from hours/days of missed work. The resultant psychological impact of rhinoplasty can also be significant. Furthermore, the health care burden from psychological pressures of nasal deformities/aesthetic shortcomings, surgical infections, surgical pain, side effects from antibiotics, and nasal packing materials must also be considered for these patients. Prior to this guideline, limited literature existed on standard care considerations for pre- and postsurgical management and for standard surgical practice to ensure optimal outcomes for patients undergoing rhinoplasty. The impetus for this guideline is to utilize current evidence-based medicine practices and data to build unanimity regarding the peri- and postoperative strategies to maximize patient safety and to optimize surgical results for patients. Purpose The primary purpose of this guideline is to provide evidence-based recommendations for clinicians who either perform rhinoplasty or are involved in the care of a rhinoplasty candidate, as well as to optimize patient care, promote effective diagnosis and therapy, and reduce harmful or unnecessary variations in care. The target audience is any clinician or individual, in any setting, involved in the management of these patients. The target patient population is all patients aged ≥15 years. The guideline is intended to focus on knowledge gaps, practice variations, and clinical concerns associated with this surgical procedure; it is not intended to be a comprehensive reference for improving nasal form and function after rhinoplasty. Recommendations in this guideline concerning education and counseling to the patient are also intended to include the caregiver if the patient is <18 years of age. Action Statements The Guideline Development Group made the following recommendations: (1) Clinicians should ask all patients seeking rhinoplasty about their motivations for surgery and their expectations for outcomes, should provide feedback on whether those expectations are a realistic goal of surgery, and should document this discussion in the medical record. (2) Clinicians should assess rhinoplasty candidates for comorbid conditions that could modify or contraindicate surgery, including obstructive sleep apnea, body dysmorphic disorder, bleeding disorders, or chronic use of topical vasoconstrictive intranasal drugs. (3) The surgeon, or the surgeon's designee, should evaluate the rhinoplasty candidate for nasal airway obstruction during the preoperative assessment. (4) The surgeon, or the surgeon's designee, should educate rhinoplasty candidates regarding what to expect after surgery, how surgery might affect the ability to breathe through the nose, potential complications of surgery, and the possible need for future nasal surgery. (5) The clinician, or the clinician's designee, should counsel rhinoplasty candidates with documented obstructive sleep apnea about the impact of surgery on nasal airway obstruction and how obstructive sleep apnea might affect perioperative management. (6) The surgeon, or the surgeon's designee, should educate rhinoplasty patients before surgery about strategies to manage discomfort after surgery. (7) Clinicians should document patients' satisfaction with their nasal appearance and with their nasal function at a minimum of 12 months after rhinoplasty. The Guideline Development Group made recommendations against certain actions: (1) When a surgeon, or the surgeon's designee, chooses to administer perioperative antibiotics for rhinoplasty, he or she should not routinely prescribe antibiotic therapy for a duration >24 hours after surgery. (2) Surgeons should not routinely place packing in the nasal cavity of rhinoplasty patients (with or without septoplasty) at the conclusion of surgery. The panel group made the following statement an option: (1) The surgeon, or the surgeon's designee, may administer perioperative systemic steroids to the rhinoplasty patient.

Design criteria and candidate electrical power systems for a reusable Space Shuttle booster.

NASA Technical Reports Server (NTRS)

Merrifield, D. V.

1972-01-01

This paper presents the results of a preliminary study to establish electrical power requirements, investigate candidate power sources, and select a representative power generation concept for the NASA Space Shuttle booster stage. Design guidelines and system performance requirements are established. Candidate power sources and combinations thereof are defined and weight estimates made. The selected power source concept utilizes secondary silver-zinc batteries, engine-driven alternators with constant speed drive, and an airbreathing gas turbine. The need for cost optimization, within safety, reliability, and performance constraints, is emphasized as being the most important criteria in design of the final system.

Epigenetic discrimination of identical twins from blood under the forensic scenario.

PubMed

Vidaki, Athina; Díez López, Celia; Carnero-Montoro, Elena; Ralf, Arwin; Ward, Kirsten; Spector, Timothy; Bell, Jordana T; Kayser, Manfred

2017-11-01

Monozygotic (MZ) twins share the same STR profile, demonstrating a practical problem in forensic casework. DNA methylation has provided a suitable resource for MZ twin differentiation; however, studies addressing the forensic feasibility are lacking. Here, we investigated epigenetic MZ twin differentiation from blood under the forensic scenario comprising i) the discovery of candidate markers in reference-type blood DNA via genome-wide analysis, ii) the technical validation of candidate markers in reference-type blood DNA using a suitable targeted method, and iii) the analysis of the validated markers in trace-type DNA. Genome-wide methylation analysis in blood DNA from 10 MZ twin pairs resulted in 19-111 twin-differentially methylated sites (tDMSs) per pair with >0.3 twin-to-twin differences. Considering all top three candidate tDMSs across all pairs in the technical validation based on methylation-specific qPCR, 67.85% generated >0.1 twin-to-twin differences. Of the validated tDMSs, 68.4% showed >0.1 twin-to-twin differences with qPCR in trace-type DNA across 8 pairs. Using an updated marker selection strategy, 8 additional candidate tDMSs were obtained for an example MZ pair, of which 7 showed >0.1 twin-to-twin differences in both reference- and trace-type DNA. Lastly, we introduce a high-resolution melting curve analysis of the entire fragment that can complement the proposed approach. Overall, our study demonstrates the general feasibility of epigenetic twin differentiation in the forensic context and highlights that the number of informative tDMSs in the final trace DNA analysis is crucial, as some candidate markers identified in reference DNA were shown not informative in the trace DNA due to various, including technical, reasons. Future studies will need to address the optimal number of epigenetic markers required for reliable identification of MZ twin individuals including statistical considerations. Copyright © 2017 Elsevier B.V. All rights reserved.

Guidelines for the selection of chemical-protective clothing. Volume 2. Technical and reference manual. (3rd Edition). Report for January 1985-March 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwope, A.D.; Costas, P.P.; Jackson, J.O.

1987-02-01

A variety of protective-clothing items are commercially available for emergency response and other applications where chemical hazards may be encountered. Data and information for selecting chemical-protective clothing is either not available or is inconsistant from source to source. In 1983, the U.S. Environmental Protection Agency sponsored the development of chemical-protective clothing selection guidelines to assist their own Office of Health and Safety in providing guidance to personnel, primarily EPA employees and contractors, working on hazardous-waste sites. These guidelines allowed a user to select an appropriate protective material for a specific chemical, select a clothing item (glove, suit, etc.), and thenmore » determine which manufacturers offered the clothing item in the recommended material. The U.S, Coast Guard Office of Research and Development and the EPA have supplemented these guidelines with additional data on material chemical resistance, material physical properties, clothing design features, and specific-vendor products. A chapter has been added for selecting chemical-protective suits. These guidelines contain data for over 750 chemicals and 700 clothing products. Volume I provides performance information and recommendations for selecting different types of protective clothing. Volume II contains a detailed technical discussion, and the data on which Volume I recommendations are based. The U.S. Coast Guard intends to use these guidelines for protective-clothing selection by its National Strike Force and Marine Safety Offices.« less

GUIDELINES FOR STATE VOCATIONAL AGRICULTURE CURRICULUM MATERIALS SERVICES, A RESEARCH REPORT OF A GRADUATE STUDY. RESEARCH SERIES IN AGRICULTURAL EDUCATION.

ERIC Educational Resources Information Center

RIDENOUR, HARLAN E.; WOODIN, RALPH J.

PROBLEMS OF VOCATIONAL AGRICULTURE TEACHERS IN KEEPING ABREAST OF TECHNICAL KNOWLEDGE AND OBTAINING OR PREPARING MATERIALS STRUCTURED IN LOGICAL SEQUENCE FOR TEACHING PROMPTED A STUDY TO DEVELOP GUIDELINES FOR ORGANIZING AND OPERATING A STATEWIDE VOCATIONAL AGRICULTURE CURRICULUM MATERIALS SERVICE. A SURVEY OF 48 STATE DIRECTORS AND 48 STATE…

Technical basis for implementation of remote reading capabilities for radiological control instruments at tank farms

DOE Office of Scientific and Technical Information (OSTI.GOV)

PIERSON, R.M.

1999-10-27

This document provides the technical basis for use of remote reading capabilities with radiological control instruments at River Protection Project facilities. The purpose of this document is to evaluate applications of remote reading capabilities with Radiological Control instrumentation to allow continuous monitoring of radiation dose rates at River Protection Project (RPP) facilities. In addition this document provides a technical basis and implementing guidelines for remote monitoring of dose rates and their potential contribution to maintaining radiation exposures ALARA.

Clinical inertia, uncertainty and individualized guidelines.

PubMed

Reach, G

2014-09-01

Doctors often do not follow the guidelines of good practice based on evidence-based medicine, and this "clinical inertia" may represent an impediment to efficient care. The aims of this article are as follows: 1) to demonstrate that this phenomenon is often the consequence of a discrepancy between the technical rationality of evidence-based medicine and the modes of reasoning of physicians practiced in "real-life", which is marked by uncertainty and risk; 2) to investigate in this context the meaning of the recent, somewhat paradoxical, concept of "individualized guidelines"; and 3) to revisit the real, essentially pedagogical, place of guidelines in medical practice. Copyright © 2014. Published by Elsevier Masson SAS.

ICH guidelines--implementation of the 3Rs (refinement, reduction, and replacement): incorporating best scientific practices into the regulatory process.

PubMed

Ohno, Yasuo

2002-01-01

An overview of the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) is described. ICH was established through cooperation of the regulatory agencies and industrial parties of three main regions involved in pharmaceuticals: the European Union, the United States, and Japan. The purpose of the ICH is to make recommendations to achieve greater harmonization regarding interpretation and application of technical guidelines and requirements for product registration in an effort to reduce or obviate the need to duplicate the testing carried out during the research and development of new medicines. The main purpose of ICH was not to foster the 3Rs per se; however, harmonization of guidelines has eliminated duplications of similar tests to satisfy the specific requirements of each region. The ICH process has contributed to mutual understanding of the regulatory requirements and has decreased the number of unnecessary animal experiments. Specific examples of the contributions of ICH harmonization to the 3Rs are described.

Debris mitigation measures by satellite design and operational methods - Findings from the DLR space debris End-to-End Service

NASA Astrophysics Data System (ADS)

Sdunnus, H.; Beltrami, P.; Janovsky, R.; Koppenwallner, G.; Krag, H.; Reimerdes, H.; Schäfer, F.

Debris Mitigation has been recognised as an issue to be addressed by the space faring nations around the world. Currently, there are various activities going on, aiming at the establishment of debris mitigation guidelines on various levels, reaching from the UN down to national space agencies. Though guidelines established on the national level already provide concrete information how things should be done (rather that specifying what should be done or providing fundamental principles) potential users of the guidelines will still have the need to explore the technical, management, and financial implications of the guidelines for their projects. Those questions are addressed by the so called "Space Debris End-to-End Service" project, which has been initiated as a national initiative of the German Aerospace Centre (DLR). Based on a review of already existing mitigation guidelines or guidelines under development and following an identification of needs from a circle of industrial users the "End-to-End Service Gu idelines" have been established for designer and operators of spacecraft. The End-to-End Service Guidelines are based on requirements addressed by the mitigation guidelines and provide recommendations how and when the technical consideration of the mitigation guidelines should take place. By referencing requirements from the mitigation guidelines, the End-to-End Service Guidelines address the consideration of debris mitigation measures by spacecraft design and operational measures. This paper will give an introduction to the End-to-End Service Guidelines. It will focus on the proposals made for mitigation measures by the S/C system design, i.e. on protective design measures inside the spacecraft and on design measures, e.g. innovative protective (shielding) systems. Furthermore, approaches on the analytical optimisation of protective systems will be presented, aiming at the minimisation of shield mass under conservation of the protective effects. On the operational side, the possibility to support mitgation measures supported through radar observation will be addressed as well as measures to minimise the risk during the satellite reentry phase by the choice of proper reentry parameters and spacecraft materials and design options.

10 CFR 960.3-1-4 - Evidence for siting decisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The siting... recommendation of a candidate site for the development of a repository. Each of these decisions will be supported...

A living wage for research subjects.

PubMed

Phillips, Trisha B

2011-01-01

Offering cash payments to research subjects is a common recruiting method, but this practice continues to be controversial because of its potential to compromise the protection of human subjects. Federal regulations and guidelines currently allow researchers to pay subjects for participation, but they say very little about how much researchers can pay their subjects. This paper argues that the federal regulations and guidelines should implement a standard payment formula. It argues for a wage payment model, and critically examines three candidates for a base wage: the nonfarm production wage, the FLSA minimum wage, and a living wage. After showing that the nonfarm production wage is too high to satisfy ethical criteria, and the minimum wage is too low, this paper concludes that the wage payment model with a base wage equivalent to a living wage is the best candidate for a standard payment formula in human subjects research. © 2011 American Society of Law, Medicine & Ethics, Inc.

The World Health Organization's safe abortion guidance document.

PubMed

Van Look, Paul F A; Cottingham, Jane

2013-04-01

We discuss the history of the World Health Organization's (WHO's) development of guidelines for governments on providing safe abortion services, which WHO published as Safe Abortion: Technical and Policy Guidance for Health Systems in 2003 and updated in 2012. We show how the recognition of the devastating impact of unsafe abortion on women's health and survival, the impetus of the International Conference on Population and Development and its five-year follow-up, and WHO's progressive leadership at the end of the century enabled the organization to elaborate guidance on providing safe abortion services. Guideline formulation involved extensive review of published evidence, an international technical expert meeting to review the draft document, and a protracted in-house review by senior WHO management.

ISU Team Project: An Integral View on Space Debris Mitigation and Removal

NASA Astrophysics Data System (ADS)

Maier, Philipp; Ricote Navarro, Carmon; Jehn, Rudiger; Gini, Andrea; Faure, Pauline; Adriaensen, Maarten; Datta, Iman; Hilbich, Daniel; Jacimovic, Aleksandar; Jacques, Lionel; Penent, Guilhem; Sinn, Thomas; Shioi, Hiroaki

2013-08-01

The issue of space debris poses challenges not only in technical, but also legal, political and economic dimensions. A sustainable solution needs to take into account all of them. This paper investigates such a potential solution in a multidisciplinary approach. To this end, it addresses the effectiveness of the existing debris mitigation guidelines, and identifies technical improvements for mitigation. It continues examining technical concepts for debris removal and performing proper cost-benefit trade-offs. The results of new simulations to assess the damage cost caused by space debris are presented. Based on these findings, an organizational framework and political recommendations are developed which will enable a sustainable use of space starting in 2020. The findings are compiled into a roadmap, which outlines 1) a path to the full adherence to debris mitigation guidelines and 2) the removal of ten large pieces of debris per year by a dedicated international organization, including expected expenditures necessary for its implementation.

Mixed Initiative Visual Analytics Using Task-Driven Recommendations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, Kristin A.; Cramer, Nicholas O.; Israel, David

2015-12-07

Visual data analysis is composed of a collection of cognitive actions and tasks to decompose, internalize, and recombine data to produce knowledge and insight. Visual analytic tools provide interactive visual interfaces to data to support tasks involved in discovery and sensemaking, including forming hypotheses, asking questions, and evaluating and organizing evidence. Myriad analytic models can be incorporated into visual analytic systems, at the cost of increasing complexity in the analytic discourse between user and system. Techniques exist to increase the usability of interacting with such analytic models, such as inferring data models from user interactions to steer the underlying modelsmore » of the system via semantic interaction, shielding users from having to do so explicitly. Such approaches are often also referred to as mixed-initiative systems. Researchers studying the sensemaking process have called for development of tools that facilitate analytic sensemaking through a combination of human and automated activities. However, design guidelines do not exist for mixed-initiative visual analytic systems to support iterative sensemaking. In this paper, we present a candidate set of design guidelines and introduce the Active Data Environment (ADE) prototype, a spatial workspace supporting the analytic process via task recommendations invoked by inferences on user interactions within the workspace. ADE recommends data and relationships based on a task model, enabling users to co-reason with the system about their data in a single, spatial workspace. This paper provides an illustrative use case, a technical description of ADE, and a discussion of the strengths and limitations of the approach.« less

JPRS Report, Science & Technology, USSR: Science & Technology Policy

DTIC Science & Technology

1990-02-28

Biliary, Post-Operative, and Chronic Pancreatites ." 12. Doctor of Technical Sciences Oleg Nikolayevich Kukushkin and Candidate of Technical...Motorygin: What is amazing here: established production in case of the absence of a market and in case of a chronic shortage does not like innovations...tremendous losses due to chronic shortages of serviceable equipment. Dozens of original technological processes are aimed at solving this problem

1986 Proteus Survey: Technical Manual and Codebook

DTIC Science & Technology

1992-06-01

Officer Candidate School and Direct Commission) and by gender. Female officers were oversampled (30% in the sample versus ap- proximately 16% in the...analyze the effects of this change in policy both on the individual cadets and on the Academy and to study the process of coeducation over four years...Candidate School (OCS), and Direct Commissioning (DC). Approximately 1,000 officers were randomly selected from each commissioning year group 1980-1984 from

Technical Desiderata for the Integration of Genomic Data into Electronic Health Records

PubMed Central

Masys, Daniel R.; Jarvik, Gail P.; Abernethy, Neil F.; Anderson, Nicholas R.; Papanicolaou, George J.; Paltoo, Dina N.; Hoffman, Mark A.; Kohane, Isaac S.; Levy, Howard P.

2012-01-01

The era of “Personalized Medicine,” guided by individual molecular variation in DNA, RNA, expressed proteins and other forms of high volume molecular data brings new requirements and challenges to the design and implementation of Electronic Health Records (EHRs). In this article we describe the characteristics of biomolecular data that differentiate it from other classes of data commonly found in EHRs, enumerate a set of technical desiderata for its management in healthcare settings, and offer a candidate technical approach to its compact and efficient representation in operational systems. PMID:22223081

Ground System Survivability Overview

DTIC Science & Technology

2012-03-27

Avoidance Blast Mitigation Optimization Customer ILIR RDT&E Funding 5.0 % 0.5% GSS has a proven, technically proficient workforce that meets...Evaluation of Defensive-Aid Suites (ARMED) Common Automatic Fire Extinguishing System ( CAFES ) Transparent Armor Development Ground Combat Vehicle...Survey TRADOC (WFO, CNA, etc) Voice of the Customer Sy st em s En gi ne er in g Publish overarching MIL-STD, design guidelines, technical

PP167. A process evaluation of an innovative implementation strategy of the Dutch guidelines on hypertensive disorders in pregnancy using a computerized decision support system.

PubMed

Luitjes, S; Mesri, K; Wouters, M; van Tulder, M; Hermens, R

2012-07-01

Hypertensive disorders in pregnancy remain the leading cause of maternal mortality in the Netherlands. The Dutch Society of Obstetrics and Gynecology (NVOG) has developed evidence-based guidelines on the management of hypertension in pregnancy. Previous studies showed a low adherence rate to other NVOG guidelines and a large variation in usual care in different hospitals. In the BIG CHANGE trial an innovative implementation strategy of the NVOG guidelines on hypertension using a web-based application (BOS, by Giant Soft, Leeuwarden, The Netherlands) was compared to a common strategy of professional audit and feedback. In this study a process evaluation of BOS has been done, analyzing its efficiency, barriers and formulate improvement points. Gynecologists, residents and clinical midwives from seven hospitals using BOS were asked to fill in the questionnaire. A questionnaire was developed on the following items: efficiency, barriers and improvement. Thirty four completed questionnaires useful for analysis. 63.6% of the respondent also consulted the NVOG guideline or local protocol, mainly for confirmation of information, background information, medication. Technical problems were found in 44.1%. Positive opinions on user friendliness varied from 73.5% to 100%. No significant difference was found between the user frequency of BOS compared to the NVOG guidelines or local protocol, or between the time needed to consult them. Improvements mentioned by the respondents were mainly regarding the lay-out. Most respondents (85.3%) found it useful to make a computer based support system for other guidelines and 79.4% would also use this. BOS is regarded suitable as an instrument for implementing guidelines and respondents find it useful to develop it for other guidelines as well. Technical problems and poor implementation are important areas of improvement. Copyright © 2012. Published by Elsevier B.V.

A New Security Paradigm for Anti-Counterfeiting: Guidelines and an Implementation Roadmap

NASA Astrophysics Data System (ADS)

Lehtonen, Mikko

Product counterfeitingand piracy continue to plague brand and trademark owners across industry sectors. This chapter analyses the reasons for ineffectiveness of past technical anti-counterfeitingstrategies and formulates managerial guidelines for effective use of RFID in anti-counterfeiting. An implementation roadmap toward secure authentication of products tagged with EPC Gen-2 tags is proposed and possible supply chain locations for product checks are discussed.

Technical standards and guidelines: molecular genetic testing for ultra-rare disorders.

PubMed

Maddalena, Anne; Bale, Sherri; Das, Soma; Grody, Wayne; Richards, Sue

2005-10-01

These standards and guidelines are designed primarily as an educational resource for clinical laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines does not necessarily ensure a successful medical outcome. These standards and guidelines should not be considered inclusive of all proper procedures and tests or exclusive of other procedures and tests that are reasonably directed to obtaining the same results. In determining the propriety of any specific procedure or test, the clinical molecular geneticist should apply his or her own professional judgment to the specific clinical circumstances presented by the individual patient or specimen. It may be prudent, however, to document in the laboratory record the rationale for any significant deviation from these standards and guidelines.

California highway barrier aesthetics

DOT National Transportation Integrated Search

2002-06-01

This report will familiarize designers with current barrier design options, and encourage appropriate aesthetic considerations to develop visually pleasing context sensitive solutions for highway projects. Technical guidelines allow integral color, p...

40 CFR 52.2633 - Stack height regulations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Wyoming § 52.2633 Stack height... with the “Guideline for Determination of Good Engineering Practice Stack Height (Technical Support...

7 CFR 2812.2 - Eligibility.

Code of Federal Regulations, 2010 CFR

2010-01-01

... involved in the conduct of technical and scientific educational and research activities. ... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

Assessment of the Warrant Officer Technical and Tactical Certification Course (WOTTC)

DTIC Science & Technology

2009-06-01

training and deployment as part of an operational detachment. In addition, SF candidates who attended the WOCS tended to be older, more experienced...and able to demonstrate higher levels of task and skill proficiency than Soldiers from other MOSs. Leaders at the U.S. Army Special Operations ...deployment as part of an operational detachment. In addition, SF candidates who attended the WOCS tended to be older, more experienced, and able to

Validation of SmartRank: A likelihood ratio software for searching national DNA databases with complex DNA profiles.

PubMed

Benschop, Corina C G; van de Merwe, Linda; de Jong, Jeroen; Vanvooren, Vanessa; Kempenaers, Morgane; Kees van der Beek, C P; Barni, Filippo; Reyes, Eusebio López; Moulin, Léa; Pene, Laurent; Haned, Hinda; Sijen, Titia

2017-07-01

Searching a national DNA database with complex and incomplete profiles usually yields very large numbers of possible matches that can present many candidate suspects to be further investigated by the forensic scientist and/or police. Current practice in most forensic laboratories consists of ordering these 'hits' based on the number of matching alleles with the searched profile. Thus, candidate profiles that share the same number of matching alleles are not differentiated and due to the lack of other ranking criteria for the candidate list it may be difficult to discern a true match from the false positives or notice that all candidates are in fact false positives. SmartRank was developed to put forward only relevant candidates and rank them accordingly. The SmartRank software computes a likelihood ratio (LR) for the searched profile and each profile in the DNA database and ranks database entries above a defined LR threshold according to the calculated LR. In this study, we examined for mixed DNA profiles of variable complexity whether the true donors are retrieved, what the number of false positives above an LR threshold is and the ranking position of the true donors. Using 343 mixed DNA profiles over 750 SmartRank searches were performed. In addition, the performance of SmartRank and CODIS were compared regarding DNA database searches and SmartRank was found complementary to CODIS. We also describe the applicable domain of SmartRank and provide guidelines. The SmartRank software is open-source and freely available. Using the best practice guidelines, SmartRank enables obtaining investigative leads in criminal cases lacking a suspect. Copyright © 2017 Elsevier B.V. All rights reserved.

The New School-Based Learning (SBL) to Work-Based Learning (WBL) Transition Module: A Practical Implementation in the Technical and Vocational Education (TVE) System in Bahrain

NASA Astrophysics Data System (ADS)

Alseddiqi, M.; Mishra, R.; Pislaru, C.

2012-05-01

This paper diagnoses the implementation of a new engineering course entitled 'school-based learning (SBL) to work-based learning (WBL) transition module' in the Bahrain Technical and Vocational Education (TVE) learning environment. The module was designed to incorporate an innovative education and training approach with a variety of learning activities that are included in various learning case studies. Each case study was based on with learning objectives coupled with desired learning outcomes. The TVE students should meet the desired outcomes after the completion of the learning activities and assessments. To help with the implementation phase of the new module, the authors developed guidelines for each case study. The guidelines incorporated learning activities to be delivered in an integrated learning environment. The skills to be transferred were related to cognitive, affective, and technical proficiencies. The guidelines included structured instructions to help students during the learning process. In addition, technology was introduced to improve learning effectiveness and flexibility. The guidelines include learning indicators for each learning activity and were based on their interrelation with competencies to be achieved with respect to modern industrial requirements. Each learning indicator was then correlated against the type of learning environment, teaching and learning styles, examples of mode of delivery, and assessment strategy. Also, the learning activities were supported by technological features such as discussion forums for social perception and engagement and immediate feedback exercises for self-motivation. Through the developed module, TVE teachers can effectively manage the teaching and learning process as well as the assessment strategy to satisfy students' individual requirements and enable them to meet workplace requirements.

Orientaciones Tecnicas para el Mejoramiento de la Administracion Educacional--Necesidades, Posibilidades y Perspectivas (Technical Guidelines on the Improvement of Educational Administration--Needs, Possibilities, and Perspectives).

ERIC Educational Resources Information Center

Valle, Victor M.

The success of development programs in educational systems is dependent, to a large extent, on the quality and relevancy of their management. Many worthwhile, well conceived and planned educational reforms have failed due to poor management. Therefore, both ministries of education and international organizations of technical cooperation have…

Strategies for Implementing AIDS/HIV Policy Guidelines in Developmental and Mental Health Services: A Background and Checklist for Advocates. AIDS Technical Report, No. 3.

ERIC Educational Resources Information Center

Harvey, David C.

This technical report is part of a series on AIDS/HIV (Acquired Immune Deficiency Syndrome/Human Immunodeficiency Virus) and is intended to help link various legal advocacy organizations providing services to persons with mental illness or developmental disabilities. Through a series of case examples, questions, background information, and…

NATO Guidelines on Human Engineering Testing and Evaluation

DTIC Science & Technology

2001-05-01

1980s and is known as Manpower, Personnel, and Training Integration (MANPRINT). The objective of this comprehensive management and technical effort is...systems under benign test conditions, using test subjects who are considerably more knowledeable of the system than the eventual users of the system will...Technical Management , Aeronautical Systems Division, Air Force Systems Command. Itoh, Y., Hayashi, Y., Tsukui, L, and Saito, S. (1989). Heart rate

76 FR 77228 - Request for Nominations of Experts to the Office of Research and Development's Board of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... will consider candidates from the environmental scientific/technical fields, human health care... physics, aerosol chemistry, aerosol physics); Analytical Chemistry; Green Chemistry; Endocrinology...

Setting Housing Standards to Improve Global Health

PubMed Central

Howden-Chapman, Philippa; Roebbel, Nathalie

2017-01-01

Developing World Health Organization international guidelines is a highly formal process. Yet the resulting guidelines, which Member States are encouraged, but not required to adopt, are a powerful way of developing rigorous policy and fostering implementation. Using the example of the housing and health guidelines, which are currently being finalised, this paper outlines the process for developing WHO guidelines. This includes: forming a Guidelines Review Group that represents all regions of the world, and ensures gender balance and technical expertise; identifying key health outcomes of interest; commissioning systematic reviews of the evidence; assessing the evidence; and formulating recommendations. The strength of each recommendation is assessed based on the quality of the evidence, along with consideration of issues such as equity, acceptability, and feasibility of the implementation of the recommendation. The proposed housing guidelines will address: cold and hot indoor temperatures, home injuries, household crowding, accessibility and access to active travel infrastructure. PMID:29232827

10 CFR 960.5-2 - Technical guidelines.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., operation, and closure. The first group includes conditions on population density and distribution, site... the surface characteristics of the site, the characteristics of the host rock and surrounding strata...

10 CFR 960.5-2 - Technical guidelines.

Code of Federal Regulations, 2011 CFR

2011-01-01

..., operation, and closure. The first group includes conditions on population density and distribution, site... the surface characteristics of the site, the characteristics of the host rock and surrounding strata...

10 CFR 960.5-2 - Technical guidelines.

Code of Federal Regulations, 2013 CFR

2013-01-01

..., operation, and closure. The first group includes conditions on population density and distribution, site... the surface characteristics of the site, the characteristics of the host rock and surrounding strata...

10 CFR 960.5-2 - Technical guidelines.

Code of Federal Regulations, 2012 CFR

2012-01-01

..., operation, and closure. The first group includes conditions on population density and distribution, site... the surface characteristics of the site, the characteristics of the host rock and surrounding strata...

The World Health Organization’s Safe Abortion Guidance Document

PubMed Central

Van Look, Paul F. A.; Cottingham, Jane

2013-01-01

We discuss the history of the World Health Organization’s (WHO’s) development of guidelines for governments on providing safe abortion services, which WHO published as Safe Abortion: Technical and Policy Guidance for Health Systems in 2003 and updated in 2012. We show how the recognition of the devastating impact of unsafe abortion on women’s health and survival, the impetus of the International Conference on Population and Development and its five-year follow-up, and WHO’s progressive leadership at the end of the century enabled the organization to elaborate guidance on providing safe abortion services. Guideline formulation involved extensive review of published evidence, an international technical expert meeting to review the draft document, and a protracted in-house review by senior WHO management. PMID:23409886

ERIC Processing Manual. Rules and Guidelines for the Acquisition, Selection, and Technical Processing of Documents and Journal Articles by the Various Components of the ERIC Network.

ERIC Educational Resources Information Center

Brandhorst, Ted, Ed.; And Others

This loose-leaf manual provides the detailed rules, guidelines, and examples to be used by the components of the Educational Resources Information Center (ERIC) Network in acquiring and selecting documents and in processing them (i.e., cataloging, indexing, abstracting) for input to the ERIC computer system and subsequent announcement in…

Guidelines for preparing software user documentation

NASA Technical Reports Server (NTRS)

Miller, Diane F.

1987-01-01

Clear, easy-to-use software user's manuals make strong demands on special technical communication techniques. Principles and guidelines are given for analyzing the audience and dealing with wide-ranging backgrounds of potential users. Types of information to be included in a complete manual are suggested, with a technique for creating a user-oriented rather than process-oriented organization. Accuracy verification is emphasized. Simple tips are gievn for formatting for quick comprehension and reference, for deciding on packaging, for creating helpful illustrations and examples, and for setting up clear and consistent conventions. Simple guidelines are offered for writing clearly and concisely and for editing.

Long life assurance study for manned spacecraft long life hardware. Volume 1: Summary of long life assurance guidelines

NASA Technical Reports Server (NTRS)

1972-01-01

A long life assurance program for the development of design, process, test, and application guidelines for achieving reliable spacecraft hardware was conducted. The study approach consisted of a review of technical data performed concurrently with a survey of the aerospace industry. The data reviewed included design and operating characteristics, failure histories and solutions, and similar documents. The topics covered by the guidelines are reported. It is concluded that long life hardware is achieved through meticulous attention to many details and no simple set of rules can suffice.

Guidelines of the Design of Electropyrotechnic Firing Circuit for Unmanned Flight and Ground Test Projects

NASA Technical Reports Server (NTRS)

Gonzalez, Guillermo A.; Lucy, Melvin H.; Massie, Jeffrey J.

2013-01-01

The NASA Langley Research Center, Engineering Directorate, Electronic System Branch, is responsible for providing pyrotechnic support capabilities to Langley Research Center unmanned flight and ground test projects. These capabilities include device selection, procurement, testing, problem solving, firing system design, fabrication and testing; ground support equipment design, fabrication and testing; checkout procedures and procedure?s training to pyro technicians. This technical memorandum will serve as a guideline for the design, fabrication and testing of electropyrotechnic firing systems. The guidelines will discuss the entire process beginning with requirements definition and ending with development and execution.

Systematic review of guidelines for management of intermediate hepatocellular carcinoma using the Appraisal of Guidelines Research and Evaluation II instrument.

PubMed

Holvoet, Tom; Raevens, Sarah; Vandewynckel, Yves-Paul; Van Biesen, Wim; Geboes, Karen; Van Vlierberghe, Hans

2015-10-01

Hepatocellular carcinoma is the second leading cause of cancer-related mortality worldwide. Multiple guidelines have been developed to assist clinicians in its management. We aimed to explore methodological quality of these guidelines focusing on treatment of intermediate hepatocellular carcinoma by transarterial chemoembolization. A systematic search was performed for Clinical Practice Guidelines and Consensus statements for hepatocellular carcinoma management. Guideline quality was appraised using the Appraisal of Guidelines Research and Evaluation II instrument, which rates guideline development processes across 6 domains: 'Scope and purpose', 'Stakeholder involvement', 'Rigour of development', 'Clarity of presentation', 'Applicability' and 'Editorial independence'. Thematic analysis of guidelines was performed to map differences in recommendations. Quality of 21 included guidelines varied widely, but was overall poor with only one guideline passing the 50% mark on all domains. Key recommendations as (contra)indications and technical aspects were inconsistent between guidelines. Aspects on side effects and health economics were mainly neglected. Methodological quality of guidelines on transarterial chemoembolization in hepatocellular carcinoma management is poor. This results in important discrepancies between guideline recommendations, creating confusion in clinical practice. Incorporation of the Appraisal of Guidelines Research and Evaluation II instrument in guideline development may improve quality of future guidelines by increasing focus on methodological aspects. Copyright © 2015 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Definition of experiments and instruments for a communication/navigation research laboratory. Volume 2: Experiment selection

NASA Technical Reports Server (NTRS)

1972-01-01

The selection and definition of candidate experiments and the associated experiment instrumentation requirements are described. Information is presented that addresses the following study objectives: (1) determine specific research and technology needs in the comm/nav field through a survey of the scientific/technical community; (2) develop manned low earth orbit space screening criteria and compile lists of potential candidate experiments; (3) in Blue Book format, define and describe selected candidate experiments in sufficient detail to develop laboratory configuration designs and layouts; and (4) develop experiment time phasing criteria and recommend a payload for sortie can/early laboratory missions.

Shifting from presumptive to test-based management of malaria - technical basis and implications for malaria control in Ghana.

PubMed

Baiden, F; Malm, K; Bart-Plange, C; Hodgson, A; Chandramohan, D; Webster, J; Owusu-Agyei, S

2014-06-01

The presumptive approach was the World Health Organisation (WHO) recommended to the management of malaria for many years and this was incorporated into syndromic guidelines such as the Integrated Management of Childhood Illnesses (IMCI). In early 2010 however, WHO issued revised treatment guidelines that call for a shift from the presumptive to the test-based approach. Practically, this implies that in all suspected cases, the diagnosis of uncomplicated malaria should be confirmed using rapid test before treatment is initiated. This revision effectively brings to an end an era of clinical practice that span several years. Its implementation has important implications for the health systems in malaria-endemic countries. On the basis of research in Ghana and other countries, and evidence from program work, the Ghana National Malaria Control Program has issued revised national treatment guidelines that call for implementation of test-based management of malaria in all cases, and across all age groups. This article reviews the evidence and the technical basis for the shift to test-based management and examines the implications for malaria control in Ghana.

NASA Aerospace Flight Battery Program: Generic Safety, Handling and Qualification Guidelines for Lithium-Ion (Li-Ion) Batteries; Availability of Source Materials for Lithium-Ion (Li-Ion) Batteries; Maintaining Technical Communications Related to Aerospace Batteries (NASA Aerospace Battery Workshop). Volume 1, Part 1

NASA Technical Reports Server (NTRS)

Manzo, Michelle A.; Brewer, Jeffrey C.; Bugga, Ratnakumar V.; Darcy, Eric C.; Jeevarajan, Judith A.; McKissock, Barbara I.; Schmitz, Paul C.

2010-01-01

This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 1 - Volume I: Generic Safety, Handling and Qualification Guidelines for Lithium-Ion (Li-Ion) Batteries, Availability of Source Materials for Lithium-Ion (Li-Ion) Batteries, and Maintaining Technical Communications Related to Aerospace Batteries (NASA Aerospace Battery Workshop).

Writing Technical Reports for Simulation in Education for Health Professionals: Suggested Guidelines.

PubMed

Dubrowski, Adam; Alani, Sabrina; Bankovic, Tina; Crowe, Andrea; Pollard, Megan

2015-11-02

Simulation is an important training tool used in a variety of influential fields. However, development of simulation scenarios - the key component of simulation - occurs in isolation; sharing of scenarios is almost non-existent. This can make simulation use a costly task in terms of the resources and time and the possible redundancy of efforts. To alleviate these issues, the goal is to strive for an open communication of practice (CoP) surrounding simulation. To facilitate this goal, this report describes a set of guidelines for writing technical reports about simulation use for educating health professionals. Using an accepted set of guidelines will allow for homogeneity when building simulation scenarios and facilitate open sharing among simulation users. In addition to optimizing simulation efforts in institutions that are currently using simulation as an educational tool, the development of such a repository may have direct implications on developing countries, where simulation is only starting to be used systematically. Our project facilitates equivalent and global access to information, knowledge, and highest-caliber education - in this context, simulation - collectively, the building blocks of optimal healthcare.

Writing Technical Reports for Simulation in Education for Health Professionals: Suggested Guidelines

PubMed Central

Alani, Sabrina; Bankovic, Tina; Crowe, Andrea; Pollard, Megan

2015-01-01

Simulation is an important training tool used in a variety of influential fields. However, development of simulation scenarios - the key component of simulation – occurs in isolation; sharing of scenarios is almost non-existent. This can make simulation use a costly task in terms of the resources and time and the possible redundancy of efforts. To alleviate these issues, the goal is to strive for an open communication of practice (CoP) surrounding simulation. To facilitate this goal, this report describes a set of guidelines for writing technical reports about simulation use for educating health professionals. Using an accepted set of guidelines will allow for homogeneity when building simulation scenarios and facilitate open sharing among simulation users. In addition to optimizing simulation efforts in institutions that are currently using simulation as an educational tool, the development of such a repository may have direct implications on developing countries, where simulation is only starting to be used systematically. Our project facilitates equivalent and global access to information, knowledge, and highest-caliber education - in this context, simulation – collectively, the building blocks of optimal healthcare.  PMID:26677421

Cardiac Diseases Among Liver Transplant Candidates.

PubMed

Gitman, Marina; Albertz, Megan; Nicolau-Raducu, Ramona; Aniskevich, Stephen; Pai, Sher-Lu

2018-05-27

Improvements in early survival after liver transplant (LT) have allowed for the selection of LT candidates with multiple comorbidities. Cardiovascular disease is a major contributor to post-LT complications. We performed a literature search to identify the causes of cardiac disease in the LT population and to describe techniques for diagnosis and perioperative management. Since no definite guidelines for preoperative assessment (except for pulmonary heart disease) are currently available, we recommend an algorithm for preoperative cardiac work-up. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Educational Software--New Guidelines for Development.

ERIC Educational Resources Information Center

Gold, Patricia Cohen

1984-01-01

Discusses standards developed by the Educational Computer Service of the National Education Association that incorporate technical, educational, and documentation components to guide authors in the development of quality educational software. (Author/MBR)

Implementing the Aquidneck Island West Side Master Plan

EPA Pesticide Factsheets

This report describes a technical assistance project with Aquidneck Island to develop approaches for mixed-use zoning standards, design guidelines, and review processes to implement the West Side Master Plan.

7 CFR 2812.9 - Disposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Federal projects or sold and the proceeds used for technical and scientific education and research... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

2014 Korean Guidelines for Appropriate Utilization of Cardiovascular Magnetic Resonance Imaging: A Joint Report of the Korean Society of Cardiology and the Korean Society of Radiology

PubMed Central

Yoon, Yeonyee E.; Hong, Yoo Jin; Kim, Hyung-Kwan; Kim, Jeong A; Na, Jin Oh; Yang, Dong Hyun

2014-01-01

Cardiac magnetic resonance (CMR) imaging is now widely used in several fields of cardiovascular disease assessment due to recent technical developments. CMR can give physicians information that cannot be found with other imaging modalities. However, there is no guideline which is suitable for Korean people for the use of CMR. Therefore, we have prepared a Korean guideline for the appropriate utilization of CMR to guide Korean physicians, imaging specialists, medical associates and patients to improve the overall medical system performances. By addressing CMR usage and creating these guidelines we hope to contribute towards the promotion of public health. This guideline is a joint report of the Korean Society of Cardiology and the Korean Society of Radiology. PMID:25469078

2014 Korean Guidelines for Appropriate Utilization of Cardiovascular Magnetic Resonance Imaging: A Joint Report of the Korean Society of Cardiology and the Korean Society of Radiology

PubMed Central

Yoon, Yeonyee E.; Hong, Yoo Jin; Kim, Hyung-Kwan; Kim, Jeong A; Na, Jin Oh; Yang, Dong Hyun

2014-01-01

Cardiac magnetic resonance (CMR) imaging is now widely used in several fields of cardiovascular disease assessment due to recent technical developments. CMR can give physicians information that cannot be found with other imaging modalities. However, there is no guideline which is suitable for Korean people for the use of CMR. Therefore, we have prepared a Korean guideline for the appropriate utilization of CMR to guide Korean physicians, imaging specialists, medical associates and patients to improve the overall medical system performances. By addressing CMR usage and creating these guidelines we hope to contribute towards the promotion of public health. This guideline is a joint report of the Korean Society of Cardiology and the Korean Society of Radiology. PMID:25469139

RATIONALE AND SUGGESTED GUIDELINES FOR THE ESTABLISHMENT AND IMPLEMENTATION OF TWO-YEAR ASSOCIATE DEGREE NURSING PROGRAMS ADMINISTERED IN COOPERATION WITH THE VOCATIONAL-TECHNICAL EDUCATION BRANCH OF THE IOWA DEPARTMENT OF PUBLIC INSTRUCTION.

ERIC Educational Resources Information Center

KERR, ELIZABETH E.

THE PROBLEMS OF EFFECTIVELY CONCENTRATING COURSES, EFFICIENTLY USING TIME AND MONEY, PROVIDING ADEQUATE TRAINING, AND HELPING ALLEVIATE THE NURSE SHORTAGE COULD BE SOLVED BY ESTABLISHING DEFINITIVE ASSOCIATE DEGREE PROGRAMS IN NURSING. THESE WOULD QUALIFY FOR ASSISTANCE FROM THE VOCATIONAL-TECHNICAL BRANCH AND WOULD BE APPROPRIATELY ADMINISTERED…

Policy Level Information on Logistics-Oriented Research.

DTIC Science & Technology

1980-08-01

Logistics Planann and System Long-Range Management Technology Planning Evaluation of Rold Miasion of Support Organizacion Effective Cross-Service Policies...guidelines, solution procedures, etc. The documentation format (technical report, user’s manual , briefing slides, etc.) also falls into this category...CHECK AT LEAST ONE) PhD Dissertation SMaster’s Thesis 7 Memorandum L Briefing Q Technical Report 7 Software Product O Hardware Product Q7 User’s Manual

ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.

PubMed

Syngal, Sapna; Brand, Randall E; Church, James M; Giardiello, Francis M; Hampel, Heather L; Burt, Randall W

2015-02-01

This guideline presents recommendations for the management of patients with hereditary gastrointestinal cancer syndromes. The initial assessment is the collection of a family history of cancers and premalignant gastrointestinal conditions and should provide enough information to develop a preliminary determination of the risk of a familial predisposition to cancer. Age at diagnosis and lineage (maternal and/or paternal) should be documented for all diagnoses, especially in first- and second-degree relatives. When indicated, genetic testing for a germline mutation should be done on the most informative candidate(s) identified through the family history evaluation and/or tumor analysis to confirm a diagnosis and allow for predictive testing of at-risk relatives. Genetic testing should be conducted in the context of pre- and post-test genetic counseling to ensure the patient's informed decision making. Patients who meet clinical criteria for a syndrome as well as those with identified pathogenic germline mutations should receive appropriate surveillance measures in order to minimize their overall risk of developing syndrome-specific cancers. This guideline specifically discusses genetic testing and management of Lynch syndrome, familial adenomatous polyposis (FAP), attenuated familial adenomatous polyposis (AFAP), MUTYH-associated polyposis (MAP), Peutz-Jeghers syndrome, juvenile polyposis syndrome, Cowden syndrome, serrated (hyperplastic) polyposis syndrome, hereditary pancreatic cancer, and hereditary gastric cancer.

ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes

PubMed Central

Syngal, Sapna; Brand, Randall E.; Church, James M.; Giardiello, Francis M.; Hampel, Heather L.; Burt, Randall W.

2015-01-01

This guideline presents recommendations for the management of patients with hereditary gastrointestinal cancer syndromes. The initial assessment is the collection of a family history of cancers and premalignant gastrointestinal conditions and should provide enough information to develop a preliminary determination of the risk of a familial predisposition to cancer. Age at diagnosis and lineage (maternal and/or paternal) should be documented for all diagnoses, especially in first- and second-degree relatives. When indicated, genetic testing for a germline mutation should be done on the most informative candidate(s) identified through the family history evaluation and/or tumor analysis to confirm a diagnosis and allow for predictive testing of at-risk relatives. Genetic testing should be conducted in the context of pre- and post-test genetic counseling to ensure the patient's informed decision making. Patients who meet clinical criteria for a syndrome as well as those with identified pathogenic germline mutations should receive appropriate surveillance measures in order to minimize their overall risk of developing syndrome-specific cancers. This guideline specifically discusses genetic testing and management of Lynch syndrome, familial adenomatous polyposis (FAP), attenuated familial adenomatous polyposis (AFAP), MUTYH-associated polyposis (MAP), Peutz–Jeghers syndrome, juvenile polyposis syndrome, Cowden syndrome, serrated (hyperplastic) polyposis syndrome, hereditary pancreatic cancer, and hereditary gastric cancer. PMID:25645574

Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development.

PubMed

Tomar, Dheeraj S; Kumar, Sandeep; Singh, Satish K; Goswami, Sumit; Li, Li

2016-01-01

Effective translation of breakthrough discoveries into innovative products in the clinic requires proactive mitigation or elimination of several drug development challenges. These challenges can vary depending upon the type of drug molecule. In the case of therapeutic antibody candidates, a commonly encountered challenge is high viscosity of the concentrated antibody solutions. Concentration-dependent viscosity behaviors of mAbs and other biologic entities may depend on pairwise and higher-order intermolecular interactions, non-native aggregation, and concentration-dependent fluctuations of various antibody regions. This article reviews our current understanding of molecular origins of viscosity behaviors of antibody solutions. We discuss general strategies and guidelines to select low viscosity candidates or optimize lead candidates for lower viscosity at early drug discovery stages. Moreover, strategies for formulation optimization and excipient design are also presented for candidates already in advanced product development stages. Potential future directions for research in this field are also explored.

Development, Validation, and Implementation of a Clinic Nurse Staffing Guideline.

PubMed

Deeken, Debra Jean; Wakefield, Douglas; Kite, Cora; Linebaugh, Jeanette; Mitchell, Blair; Parkinson, Deidre; Misra, Madhukar

2017-10-01

Ensuring that the level of nurse staffing used to care for patients is appropriate to the setting and service intensity is essential for high-quality and cost-effective care. This article describes the development, validation, and implementation of the clinic technical skills permission list developed specifically to guide nurse staffing decisions in physician clinics of an academic medical center. Results and lessons learned in using this staffing guideline are presented.

Guidelines for computer security in general practice.

PubMed

Schattner, Peter; Pleteshner, Catherine; Bhend, Heinz; Brouns, Johan

2007-01-01

As general practice becomes increasingly computerised, data security becomes increasingly important for both patient health and the efficient operation of the practice. To develop guidelines for computer security in general practice based on a literature review, an analysis of available information on current practice and a series of key stakeholder interviews. While the guideline was produced in the context of Australian general practice, we have developed a template that is also relevant for other countries. Current data on computer security measures was sought from Australian divisions of general practice. Semi-structured interviews were conducted with general practitioners (GPs), the medical software industry, senior managers within government responsible for health IT (information technology) initiatives, technical IT experts, divisions of general practice and a member of a health information consumer group. The respondents were asked to assess both the likelihood and the consequences of potential risks in computer security being breached. The study suggested that the most important computer security issues in general practice were: the need for a nominated IT security coordinator; having written IT policies, including a practice disaster recovery plan; controlling access to different levels of electronic data; doing and testing backups; protecting against viruses and other malicious codes; installing firewalls; undertaking routine maintenance of hardware and software; and securing electronic communication, for example via encryption. This information led to the production of computer security guidelines, including a one-page summary checklist, which were subsequently distributed to all GPs in Australia. This paper maps out a process for developing computer security guidelines for general practice. The specific content will vary in different countries according to their levels of adoption of IT, and cultural, technical and other health service factors. Making these guidelines relevant to local contexts should help maximise their uptake.

Decision Support System for Disability Assessment and Intervention.

ERIC Educational Resources Information Center

Dowler, Denetta L.; And Others

1991-01-01

Constructed decision support system to aid referral of good candidates for rehabilitation from Social Security Administration to rehabilitation counselors. Three layers of system were gross screening based on policy guidelines, training materials, and interviews with experts; physical and mental functional capacity items derived from policy…

[Indications of lung transplantation: Patients selection, timing of listing, and choice of procedure].

PubMed

Morisse Pradier, H; Sénéchal, A; Philit, F; Tronc, F; Maury, J-M; Grima, R; Flamens, C; Paulus, S; Neidecker, J; Mornex, J-F

2016-02-01

Lung transplantation (LT) is now considered as an excellent treatment option for selected patients with end-stage pulmonary diseases, such as COPD, cystic fibrosis, idiopathic pulmonary fibrosis, and pulmonary arterial hypertension. The 2 goals of LT are to provide a survival benefit and to improve quality of life. The 3-step decision process leading to LT is discussed in this review. The first step is the selection of candidates, which requires a careful examination in order to check absolute and relative contraindications. The second step is the timing of listing for LT; it requires the knowledge of disease-specific prognostic factors available in international guidelines, and discussed in this paper. The third step is the choice of procedure: indications of heart-lung, single-lung, and bilateral-lung transplantation are described. In conclusion, this document provides guidelines to help pulmonologists in the referral and selection processes of candidates for transplantation in order to optimize the outcome of LT. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

Use of sexually transmitted disease risk assessment algorithms for selection of intrauterine device candidates.

PubMed

Morrison, C S; Sekadde-Kigondu, C; Miller, W C; Weiner, D H; Sinei, S K

1999-02-01

Sexually transmitted diseases (STD) are an important contraindication for intrauterine device (IUD) insertion. Nevertheless, laboratory testing for STD is not possible in many settings. The objective of this study is to evaluate the use of risk assessment algorithms to predict STD and subsequent IUD-related complications among IUD candidates. Among 615 IUD users in Kenya, the following algorithms were evaluated: 1) an STD algorithm based on US Agency for International Development (USAID) Technical Working Group guidelines: 2) a Centers for Disease Control and Prevention (CDC) algorithm for management of chlamydia; and 3) a data-derived algorithm modeled from study data. Algorithms were evaluated for prediction of chlamydial and gonococcal infection at 1 month and complications (pelvic inflammatory disease [PID], IUD removals, and IUD expulsions) over 4 months. Women with STD were more likely to develop complications than women without STD (19% vs 6%; risk ratio = 2.9; 95% CI 1.3-6.5). For STD prediction, the USAID algorithm was 75% sensitive and 48% specific, with a positive likelihood ratio (LR+) of 1.4. The CDC algorithm was 44% sensitive and 72% specific, LR+ = 1.6. The data-derived algorithm was 91% sensitive and 56% specific, with LR+ = 2.0 and LR- = 0.2. Category-specific LR for this algorithm identified women with very low (< 1%) and very high (29%) infection probabilities. The data-derived algorithm was also the best predictor of IUD-related complications. These results suggest that use of STD algorithms may improve selection of IUD users. Women at high risk for STD could be counseled to avoid IUD, whereas women at moderate risk should be monitored closely and counseled to use condoms.

Voluntary Guidelines for Methamphetamine Laboratory Cleanup - Document

EPA Pesticide Factsheets

provides technical guidance for state and local personnel responsible for meth lab cleanup, based on an extensive review of the best available science and practices, and addresses general cleanup activities, specific items/materials, sampling.

Making Self-Confidence and Communication Skills Work for the Media Specialist.

ERIC Educational Resources Information Center

Driscoll, Roberta M.

1988-01-01

Discusses the importance of incorporating technical and human relation skills to be a successful and productive media specialist, and offers guidelines for developing communication skills and self-esteem. (CLB)

GREEN OAK AS A SUSTAINABLE BUILDING MATERIAL

EPA Science Inventory

Technical documentation necessary for a project demonstrating the viability of green oak as a contemporary structural material. These will include material grading guidelines, mechanical testing, architectural construction documents and details, specifications, engineering cal...

Technical Fact Sheet – Polybrominated biphenyls (PBBs)

EPA Pesticide Factsheets

This fact sheet provides a brief summary of polybrominated biphenyls (PBB), including physical and chemical properties; environmental and health impacts; existing federal and state guidelines; detection and treatment methods; and additional sources of info

Mechanical Tunneling in Solid Rock

DOT National Transportation Integrated Search

1979-12-01

This report introduces the principles of mchanized tunneling and provides detailed guidelines for practical application. The subject is introduced with a detailed review of technical aspects and terms relating to mchanized tunneling. It discusses the...

FHWA road tunnel design guidelines

DOT National Transportation Integrated Search

2004-07-01

This document provides technical criteria and guidance for the planning and design of road tunnels. Specific areas covered include planning, studies and investigations, design, and design of construction, of tunnels and shafts. Performance concepts a...

Pavement Remaining Service Interval [Tech Brief

DOT National Transportation Integrated Search

2013-05-01

This document is a technical summary of the Federal Highway Administration reports, "Reformulated Pavement Remaining Service Life Framework" (FHWA-HRT-13-038) and "Pavement Remaining Service Interval Implementation Guidelines" (FHWA-HRT-13-050). At t...

STI Handbook: Guidelines for Producing, Using, and Managing Scientific and Technical Information in the Department of the Navy. A Handbook for Navy Scientists and Engineers on the Use of Scientific and Technical Information

DTIC Science & Technology

1992-02-01

6 What Information Should Be Included in the TR Database? 2-6 What Types of Media Can Be Used to Submit Information to the TR Database? 2-9 How Is...reports. Contract administration documents. Regulations. Commercially published books. WHAT TYPES OF MEDIA CAN BE USED TO SUBMIT INFORMATION TO THE TR...TOWARD DTIC’S WUIS DATA- BASE ? The WUIS database, used to control and report technical and management data, summarizes ongoing research and technology

Building Science-Relevant Literacy with Technical Writing in High School

DOE Office of Scientific and Technical Information (OSTI.GOV)

Girill, T R

2006-06-02

By drawing on the in-class work of an on-going literacy outreach project, this paper explains how well-chosen technical writing activities can earn time in high-school science courses by enabling underperforming students (including ESL students) to learn science more effectively. We adapted basic research-based text-design and usability techniques into age-appropriate exercises and cases using the cognitive apprenticeship approach. This enabled high-school students, aided by explicit guidelines, to build their cognitive maturity, learn how to craft good instructions and descriptions, and apply those skills to better note taking and technical talks in their science classes.

Getting the aorta pants in place: a 'community of guidance' in the evolving practice of vascular implant surgery.

PubMed

Brattheim, Berit; Faxvaag, Arild; Tjora, Aksel

2011-09-01

The evolving nature of surgical treatments creates gaps between evidence-based guidelines and actual clinical practice.This article addresses the emerging clinical practice of the EndoVascular Aneurysm Repair (EVAR), a surgical treatment of patients with Abdominal Aortic Aneurysm (AAA). Drawing on a qualitative study across three hospitals, we identified three interplaying expertise traits: the collective, the interpersonal and the technical, each being present to promote surgical work. The evolvement of EVAR is contextualized within technical artefacts and patient characteristics, along with a joint decision approach. The intertwinement between various expertise traits and contextual factors forms a 'community of guidance', nourishing further EVAR innovation without formalized institutions, evidence, training or guidelines. However, the lack of a shared context limits the transfer of evolving knowledge across hospital boundaries.

Development document for final best conventional technology effluent limitations guidelines for the pharmaceutical manufacturing point source category. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Farrell, T.; Hund, F.

1986-12-01

The document presents the technical rationale for best conventional technology (BCI) effluent limitations guidelines for the pharmaceutical manufacturing point-source category as required by the Clean Water Act of 1977 (P.L. 95-217, the Act). The document describes the technologies considered as the bases for BCT limitations. Section II of this document summarizes the rulemaking process. Sections III through V describe the technical data and engineering analyses used to develop the regulatory technology options. The costs and removals associated with each technology option for each plant and the application of the BCT cost test methodology are presented in Section VI. BCI limitationsmore » bases on the best conventional pollutant control technology are to be achieved by existing direct-discharging facilities.« less

Use of technical skills and medical devices among new registered nurses: A questionnaire study.

PubMed

Ewertsson, Mona; Gustafsson, Margareta; Blomberg, Karin; Holmström, Inger K; Allvin, Renée

2015-12-01

One comprehensive part of nursing practice is performing technical skills and handling of medical equipment. This might be challenging for new registered nurses (RNs) to do in patient-safe way. The aim of this study was to describe and compare the extent to which new RNs perform various technical skills and handle medical devices in different settings, and to investigate their possibility for continued learning in this respect. A further aim was to describe their perceptions of incident reporting related to technical skills and medical devices. A cross-sectional study with descriptive and comparative design. RNs who recently graduated from a nursing programme at three Swedish universities and had worked as a RN for up to 1 year were included in the study (n=113, response rate 57%). Data were collected by means of a postal questionnaire. Half of the RNs reported that they performed several of the listed tasks every day or every week, regardless of workplace. These tasks were most frequently performed in surgical departments. The majority of the participants (76%) stated a need of continued practical training. However, less than half of them (48%) had access to a training environment. Several participants (43%) had been involved in incidents related to technical skills or medical devices, which were not always reported. Nearly a third of the participants (31%) did not use the existing guidelines when performing technical skills, and reflection on performance was uncommon. This study highlights the importance of shared responsibilities between nurse educators and health care employers to provide learning opportunities for new RNs in technical skills, to maintain patient safety. To increase the safety culture where nursing students and new RNs understand the importance of using evidence-based guidelines and taking a reflective approach in the performance of technical tasks is needed. Copyright © 2015 Elsevier Ltd. All rights reserved.

Evaluation of Candidate Materials for Fines Filter Media in the C2 Canister

DTIC Science & Technology

1992-05-01

Philadelphia PA 19103. (5) Owens - Corning Technical Center, "Breaking Strength", Test Report 48708, October 1, 1990. (6) ASTM F778-88, "Gas Flow...strength per ASTM D1682-64. Appendix A 39 OWENS - CORNING TESTING SERVICES TECHNICAL CENTER, 2790 Columbus Rd. OWENS - CORNING FIBERGLAS CORPORATION Granville... Owens - Corning Testing Services makes no warranty, express or implied, whether of merchantability or fitness for any particular purpose, with respect to

Tactical Decision Competency of Preservice Physical Education Teacher Education Students

ERIC Educational Resources Information Center

Williams, Skip M.; Coleman, Margo M.; Henninger, Mary L.; Carlson, Kristin B.

2013-01-01

The most recent publication of the "National Standards and Guidelines for Physical Education Teacher Education" (National Association for Sport and Physical Education [NASPE], 2009) requires physical education teacher education (PETE) programs to demonstrate that teacher candidates display both tactical knowledge and physical competence.…

Lessons from an Alternative-Certification Program.

ERIC Educational Resources Information Center

Barkley, Brenda Stallion

1999-01-01

Describes Kentucky's Alternative Training Program for the Preparation of Candidates for Initial Certification, presenting the story of one individual who made a career change to teaching after 15 years as a broadcast journalist. The paper discusses state guidelines, the mentor teacher, the school district alternative training program, the…

Using Return on Investment (ROI) and Other Related Tools: Guidelines for Measuring Career and Technical Education (CTE) Internal Efficiency and External Effectiveness

ERIC Educational Resources Information Center

Kotamraju, Pradeep; Mettille, John L., III

2012-01-01

Career and technical education (CTE) is increasingly seen as a major potential contributor to the recovery of the U.S. economy. However, the effectiveness and impact of the current Carl D. Perkins Act (otherwise known as Perkins IV) that governs CTE are unclear. Is the federal investment in CTE paying off? To answer this, we need to establish the…

AgRISTARS: Foreign Commodity production forecasting. Project procedures designation and description document, volume 1

NASA Technical Reports Server (NTRS)

Waggoner, J. T.; Phinney, D. E. (Principal Investigator)

1981-01-01

The crop estimation analysis procedures documentation of the AgRISTARS - Foreign Commodity Production Forecasting Project (FCPF) is presented. Specifically it includes the technical/management documentation of the remote sensing data analysis procedures prepared in accordance with the guidelines provided in the FCPF communication/documentation standards manual. Standard documentation sets are given arranged by procedural type and level then by crop types or other technically differentiating categories.

Viewpoints from generation X: a survey of candidate and associate viewpoints on resident duty-hour regulations.

PubMed

Underwood, Willie; Boyd, Anne J; Fletcher, Kathlyn E; Lypson, Monica L

2004-06-01

The American Medical Student Association, the Committee of Interns and Residents, and Public Citizen petitioned the Occupational Safety and Health Administration for national resident duty-hour limitations. Subsequently, federal legislation was introduced to limit resident duty hours. To preempt the federal government, the Accreditation of Graduate Medical Education implemented resident duty-hour guidelines. To evaluate the viewpoints and attitudes of surgical resident and staff physicians as they pertain to the national resident duty-hour guidelines, we asked attendees of the American College of Surgeons' Candidate Associate Society Forum during the American College of Surgeons Clinical Congress meeting in 2001 to complete a self-administered questionnaire. Analyses were performed to determine the frequency of response for each survey item. Eighty-six of the 102 (84%) surgeons who attended the American College of Surgeons Forum completed the survey. Most disagreed with the federal government involvement in regulating duty hours. Although most agreed that residents should not be on call more than every third night, viewpoints varied on the other duty-hour guidelines. Most (63.4%) reported that residents should work 81 to 100 hours per week, but 11% reported that residents should work > 101 hours per week and 25.6% reported that

Measure Guideline: Deep Energy Enclosure Retrofit for Interior Insulation of Masonry Walls

DOE Office of Scientific and Technical Information (OSTI.GOV)

Musunuru, S.; Pettit, B.

2015-04-01

This Measure Guideline describes a deep energy enclosure retrofit (DEER) solution for insulating mass masonry buildings from the interior. It describes the retrofit assembly, technical details, and installation sequence for retrofitting masonry walls. Interior insulation of masonry retrofits has the potential to adversely affect the durability of the wall; this document includes a review of decision criteria pertinent to retrofitting masonry walls from the interior and the possible risk of freeze-thaw damage.

SmartWay Tractor and Trailer Logo Usage Instructions

EPA Pesticide Factsheets

View a presentation provides guidelines for SmartWay Partners on tractor and trailer logo usage, including SmartWay designated technical specifications and requirements, importance of logo display, how to obtain the logo, and logo placement.

Most Relevant Neuropathic Pain Treatment and Chronic Low Back Pain Management Guidelines: A Change Pain Latin America Advisory Panel Consensus.

PubMed

Amescua-Garcia, Cesar; Colimon, Frantz; Guerrero, Carlos; Jreige Iskandar, Aziza; Berenguel Cook, Maria; Bonilla, Patricia; Campos Kraychete, Durval; Delgado Barrera, William; Alberto Flores Cantisani, Jose; Hernandez-Castro, John Jairo; Lara-Solares, Argelia; Perez Hernandez, Concepcion; Rico, Maria Antonieta; Del Rocio Guillen Nunez, Maria; Sempertegui Gallegos, Manuel; Garcia, Joao Batista Santos

2018-03-01

Chronic pain conditions profoundly affect the daily living of a significant number of people and are a major economic and social burden, particularly in developing countries. The Change Pain Latin America (CPLA) advisory panel aimed to identify the most appropriate guidelines for the treatment of neuropathic pain (NP) and chronic low back pain (CLBP) for use across Latin America. Published systematic reviews or practice guidelines were identified by a systematic search of PubMed, the Guidelines Clearinghouse, and Google. Articles were screened by an independent reviewer, and potential candidate guidelines were selected for more in-depth review. A shortlist of suitable guidelines was selected and critically evaluated by the CPLA advisory panel. Searches identified 674 and 604 guideline articles for NP and CLBP, respectively. Of these, 14 guidelines were shortlisted for consensus consideration, with the following final selections made: "Recommendations for the pharmacological management of neuropathic pain from the Neuropathic Pain Special Interest Group in 2015-pharmacotherapy for neuropathic pain in adults: A systematic review and meta-analysis."Diagnosis and treatment of low back pain: A joint clinical practice guideline from the American College of Physicians and the American Pain Society" (2007). The selected guidelines were endorsed by all members of the CPLA advisory board as the best fit for use across Latin America. In addition, regional considerations were discussed and recorded. We have included this expert local insight and advice to enhance the implementation of each guideline across all Latin American countries.

Regulations and guidelines should be strengthened urgently for re-evaluation on post-marketing medicines in China.

PubMed

Xie, Yan-Ming; Tian, Feng

2013-07-01

This paper reviewed the situation of regulations and guidelines on post-marketing medicines in the developed countries and in China. The developed countries have accumulated a lot of empirical principles and techniques on postmarketing surveillance (also named pharmacovigilance), therefore, their regulation systems are nearly perfect. In China, the regulations on post-marketing re-evaluation and relative technical guidelines do not cover the whole aspects, even lack in some important aspects, and long-term risk management mechanisms have not been established. So it is urgent to establish new regulations and improve the regulatory system in China based on the existing regulations and guidelines, by learning from the ideas of foreign advanced regulations, then fully integrating them with China's actual conditions, and cooperating with multidisciplinary researchers.

Statistical analysis of arthroplasty data

PubMed Central

2011-01-01

It is envisaged that guidelines for statistical analysis and presentation of results will improve the quality and value of research. The Nordic Arthroplasty Register Association (NARA) has therefore developed guidelines for the statistical analysis of arthroplasty register data. The guidelines are divided into two parts, one with an introduction and a discussion of the background to the guidelines (Ranstam et al. 2011a, see pages x-y in this issue), and this one with a more technical statistical discussion on how specific problems can be handled. This second part contains (1) recommendations for the interpretation of methods used to calculate survival, (2) recommendations on howto deal with bilateral observations, and (3) a discussion of problems and pitfalls associated with analysis of factors that influence survival or comparisons between outcomes extracted from different hospitals. PMID:21619500

Technical aspects and limitations of fractional flow reserve measurement.

PubMed

Jerabek, Stepan; Kovarnik, Tomas

2018-02-27

The only indication for coronary revascularization is elimination of ischaemia. Invasive hemodynamic methods (fractional flow reserve - FFR and instantaneous wave-free ratio (iFR) are superior to coronary angiography in detection of lesions causing myocardial ischaemia. Current European guidelines for myocardial revascularization recommend using of FFR for detection of functional assessment of lesions severity in category IA and number of these procedures increases. However, routine usage of these methods requires knowledge of technical requirements and limitations. The aim of the study is to summarise good clinical practice for FFR and iFR measurements with explanation of possible technical challenges, that are necessary for increasing of measurement accuracy. Authors describe frequent technical mistakes and malpractice during invasive assessment of lesion severity in coronary arteries.

77 FR 11928 - Approval and Promulgation of Air Quality Implementation Plans; Wisconsin; Regional Haze

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-28

... monitoring, modeling, and scientific knowledge about the relationships between pollutants and visibility... for their BART modeling under the BART Guidelines, below which a BART-eligible source may be... conduct modeling to assess the impact of each of these identified candidate sources. This modeling...

Ecological Concept Development of Preservice Teacher Candidates: Opaque Empty Shells

ERIC Educational Resources Information Center

Puk, Tom; Stibbards, Adam

2010-01-01

In the Ontario publically-funded school system, there are no provincial curriculum guidelines or distinct courses for Ecological Literacy. Rather, the Ontario Ministry of Education policy is that "environmental education" should be taught in all grades and all existing subject matter. Because there are no specific Ecological Literacy…

Preparing Tomorrow's Teachers: The Field Experience. Teacher Education Yearbook IV.

ERIC Educational Resources Information Center

McIntyre, D. John, Ed.; Byrd, David M., Ed.

This yearbook provides educators with current research and practical guidelines for improving the education of teacher candidates and beginning teachers. The book has four sections, each on a particular topic and containing an overview and a response (reflections and implications). The first section focuses on contexts for effective field…

Dose Modeling Evaluations and Technical Support Document For the Authorized Limits Request for the DOE-Owned Property Outside the Limited Area, Paducah Gaseous Diffusion Plant Paducah, Kentucky

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boerner, A. J.; Maldonado, D. G.; Hansen, Tom

2012-09-01

Environmental assessments and remediation activities are being conducted by the U.S. Department of Energy (DOE) at the Paducah Gaseous Diffusion Plant (PGDP), Paducah, Kentucky. The Oak Ridge Institute for Science and Education (ORISE), a DOE prime contractor, was contracted by the DOE Portsmouth/Paducah Project Office (DOE-PPPO) to conduct radiation dose modeling analyses and derive single radionuclide soil guidelines (soil guidelines) in support of the derivation of Authorized Limits (ALs) for 'DOE-Owned Property Outside the Limited Area' ('Property') at the PGDP. The ORISE evaluation specifically included the area identified by DOE restricted area postings (public use access restrictions) and areas licensedmore » by DOE to the West Kentucky Wildlife Management Area (WKWMA). The licensed areas are available without restriction to the general public for a variety of (primarily) recreational uses. Relevant receptors impacting current and reasonably anticipated future use activities were evaluated. In support of soil guideline derivation, a Conceptual Site Model (CSM) was developed. The CSM listed radiation and contamination sources, release mechanisms, transport media, representative exposure pathways from residual radioactivity, and a total of three receptors (under present and future use scenarios). Plausible receptors included a Resident Farmer, Recreational User, and Wildlife Worker. single radionuclide soil guidelines (outputs specified by the software modeling code) were generated for three receptors and thirteen targeted radionuclides. These soil guidelines were based on satisfying the project dose constraints. For comparison, soil guidelines applicable to the basic radiation public dose limit of 100 mrem/yr were generated. Single radionuclide soil guidelines from the most limiting (restrictive) receptor based on a target dose constraint of 25 mrem/yr were then rounded and identified as the derived soil guidelines. An additional evaluation using the derived soil guidelines as inputs into the code was also performed to determine the maximum (peak) dose for all receptors. This report contains the technical basis in support of the DOE?s derivation of ALs for the 'Property.' A complete description of the methodology, including an assessment of the input parameters, model inputs, and results is provided in this report. This report also provides initial recommendations on applying the derived soil guidelines.« less

Guidelines for the Selection of Chemical Protective Clothing. Volume 2. Technical and Reference Manual.

DTIC Science & Technology

1987-02-01

Handler’s Suit for Protection from Chlorine Trifluoride and Elemental Fluorine Technical Report AFRPL-TR-71-44 (August 1971) NTIS AD731556 199 Masterman’s...Protective Clothing for Chlorine , Edition 1 Chlorine Institute Pamphlet 65, The Chlorine Institute, Inc. New York, New York, (June 1978) 15 Anon...Chemical Company Selection of Gloves for Use With Chlorinated Solvents Chlorinated Solvents Information Midland, Michigan 48640 101 Duffy, R.M., A.R.Beer

[The characterization of biosolids produced by the San Fernando wastewater treatment plant in Itagui, Antioquia, Colombia].

PubMed

Bedoya-Urrego, Katherine; Acevedo-Ruíz, José M; Peláez-Jaramillo, Carlos A; Agudelo-López, Sonia Del Pilar

2013-01-01

ABSTRACT Objective This study was aimed at evaluating pertinent physicochemical and microbiological (bacteria and parasites) parameters regarding the biosolids produced by the San Fernando wastewater treatment plant (WWTP) in Itagui, Antioquia, Colombia. Methods Twelve samples were collected and evaluated every month from January to December during 2010. The chemical, physical and microbiological tests followed the protocol described in Colombian technical guideline 5167. The protocol described in Mexican official Norm 004 (with some modifications) was used for identifying helminth ova and assessing their viability. Results All samples proved positive for Ascarislumbricoides, viable ova count ranging from 4 to 22 eggs/2gTS. Both Salmonella and Enterobacteriawere detected in all samples evaluated, the latter having 3,000 colony forming unit (CFU)/g minimum concentration. Biosolid sample values met the heavy metal concentration requirement established by national guidelines. There was no statistical association between rainfall and the pathogen's presence in the biosolids. Conclusion Our results suggested that the biosolids being produced by the San Fernando wastewater treatment plant (WWTP) could be used as organic fertilizer; however they should be treated/sanitized to meet the stipulations in Colombian technical guideline 5167.

Free smoking cessation mobile apps available in Australia: a quality review and content analysis.

PubMed

Thornton, Louise; Quinn, Catherine; Birrell, Louise; Guillaumier, Ashleigh; Shaw, Brad; Forbes, Erin; Deady, Mark; Kay-Lambkin, Frances

2017-12-01

This review aimed to identify free, high-quality, smoking cessation mobile applications (apps) that adhere to Australian smoking cessation treatment guidelines. A systematic search of smoking cessation apps was conducted using Google. The technical quality of relevant apps was rated using the Mobile Application Rating Scale. The content of apps identified as high quality was assessed for adherence to smoking cessation treatment guidelines. 112 relevant apps were identified. The majority were of poor technical quality and only six 'high-quality' apps were identified. These apps adhered to Australian treatment guidelines in part. The efficacy of two apps had been previously evaluated. In lieu of more substantial research in this area, it is suggested that the high-quality apps identified in this review may be more likely than other available apps to encourage smoking cessation. Implications for public health: Smoking cessation apps have the potential to address many barriers that prevent smoking cessation support being provided; however few high-quality smoking cessation apps are currently available in Australia, very few have been evaluated and the app market is extremely volatile. More research to evaluate smoking cessation apps, and sustained funding for evidence-based apps, is needed. © 2017 The Authors.

An adaptive toolkit for image quality evaluation in system performance test of digital breast tomosynthesis

NASA Astrophysics Data System (ADS)

Zhang, Guozhi; Petrov, Dimitar; Marshall, Nicholas; Bosmans, Hilde

2017-03-01

Digital breast tomosynthesis (DBT) is a relatively new diagnostic imaging modality for women. Currently, various models of DBT systems are available on the market and the number of installations is rapidly increasing. EUREF, the European Reference Organization for Quality Assured Breast Screening and Diagnostic Services, has proposed a preliminary Guideline - protocol for the quality control of the physical and technical aspects of digital breast tomosynthesis systems, with an ultimate aim of providing limiting values guaranteeing proper performance for different applications of DBT. In this work, we introduce an adaptive toolkit developed in accordance with this guideline to facilitate the process of image quality evaluation in DBT performance test. This toolkit implements robust algorithms to quantify various technical parameters of DBT images and provides a convenient user interface in practice. Each test is built into a separate module with configurations set corresponding to the European guideline, which can be easily adapted to different settings and extended with additional tests. This toolkit largely improves the efficiency for image quality evaluation of DBT. It is also going to evolve with the development of protocols in quality control of DBT systems.

NASA guidelines on report literature

NASA Technical Reports Server (NTRS)

1978-01-01

NASA seeks for inclusion in its Scientific and Technical Information System research reports, conference proceedings, meeting papers, monographs, and doctoral and post graduate theses which relate to the NASA mission and objectives. Topics of interest to NASA are presented.

Guidelines for deploying weather responsive operations in TxDOT traffic signals.

DOT National Transportation Integrated Search

2017-02-01

Inclement weather, such as rain, snow, fog, and ice, create special operational challenges for traffic : management agencies. This project provided Texas Department of Transportation with technical guidance : for improving safety and efficiency of si...

Molecular assays in detecting EGFR gene aberrations: an updated HER2-dependent algorithm for interpreting gene signals; a short technical report.

PubMed

Tsiambas, Evangelos; Ragos, Vasileios; Lefas, Alicia Y; Georgiannos, Stavros N; Rigopoulos, Dimitrios N; Georgakopoulos, Georgios; Stamatelopoulos, Athanasios; Grapsa, Dimitra; Syrigos, Konstantinos

2016-01-01

Purpose: Among oncogenes that have already been identified and cloned, Epidermal Growth Factor Receptor (EGFR) remains one of the most significant. Understanding its deregulation mechanisms improves critically patients' selection for personalized therapies based on modern molecular biology and oncology guidelines. Anti-EGFR targeted therapeutic strategies have been developed based on specific genetic profiles and applied in subgroups of patients suffering by solid cancers of different histogenetic origin. Detection of specific EGFR somatic mutations leads to tyrosine kinase inhibitors (TKIs) application in subsets of them. Concerning EGFR gene numerical imbalances, identification of pure gene amplification is critical for targeting the molecule via monoclonal antibodies (mAbs). In the current technical paper we demonstrate the main molecular methods applied in EGFR analyses focused also on new data in interpreting numerical imbalances based on ASCO/ACAP guidelines for HER2 in situ hybridization (ISH) clarifications.

Space station systems technology study (add-on task). Volume 3: Technology advancement program plan

NASA Technical Reports Server (NTRS)

1985-01-01

Program plans are given for an integrating controller for space station autonomy as well as for controls and displays. The technical approach, facility requirements and candidate facilities, development schedules, and resource requirements estimates are given.

Current Issues in Orbital Debris

NASA Technical Reports Server (NTRS)

Johnson, Nicholas L.

2011-01-01

During the past two decades, great strides have been made in the international community regarding orbital debris mitigation. The majority of space-faring nations have reached a consensus on an initial set of orbital debris mitigation measures. Implementation of and compliance with the IADC and UN space debris mitigation guidelines should remain a high priority. Improvements of the IADC and UN space debris mitigation guidelines should continue as technical consensus permits. The remediation of the near-Earth space environment will require a significant and long-term undertaking.

The use of a checklist improves anaesthesiologists' technical and non-technical performance for simulated malignant hyperthermia management.

PubMed

Hardy, Jean-Baptiste; Gouin, Antoine; Damm, Cédric; Compère, Vincent; Veber, Benoît; Dureuil, Bertrand

2018-02-01

Anaesthesiologists may occasionally manage life-threatening operating room (OR) emergencies. Managing OR emergencies implies real-time analysis of often complicated situations, prompt medical knowledge retrieval, coordinated teamwork and effective decision making in stressful settings. Checklists are recommended to improve performance and reduce the risk of medical errors. This study aimed to assess the usefulness of the French Society of Anaesthesia and Intensive Care's (SFAR) "Malignant Hyperthermia" (MH) checklist on a simulated episode of MH crisis and management thereof by registered anesthesiologists. Twenty-four anaesthesiologists were allocated to 2 groups (checklist and control). Their technical performance in adherence with the SFAR guidelines was assessed by a 30-point score and their non-technical performance was assessed by the Anaesthetists' Non-Technical Skills (ANTS) score. Every task completion was assessed independently. Data are shown as median (first-third quartiles). Anaesthesiologists in the checklist group had higher technical performance scores (24/30 (21.5-25) vs 18/30 (15.5-19.5), P=0.002) and ANTS scores (56.5/60 (47.5-58) vs 48.5/60 (41-50.5), P=0.024). They administered the complete initial dose of dantrolene (2mg/kg) more quickly (15.7 minutes [13.9-18.3] vs 22.4 minutes [18.6-25]) than the control group (P=0.017). However, anaesthesiologists deemed the usability of the checklist to be perfectible. Registered anaesthesiologists' use of the MH checklist during a simulation session widely improved their adherence to guidelines and non-technical skills. This study strongly suggests the benefit of checklist tools for emergency management. Notwithstanding, better awareness and training for anaesthesiologists could further improve the use of this tool. Copyright © 2017 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

A national database for essential drugs in South Africa.

PubMed

Zweygarth, M; Summers, R S

2000-06-01

In the process of drafting standard treatment guidelines for adults and children at hospital level, the Secretariat of the National Essential Drugs List Committee made use of a database designed with technical support from the School of Pharmacy, MEDUNSA. The database links the current 697 drugs on the Essential Drugs List with Standard Treatment Guidelines for over 400 conditions. It served to streamline the inclusion of different drugs and dosage forms in the various guidelines, and provided concise, updated information to other departments involved in drug procurement. From information on drug prices and morbidity, it can also be used to calculate drug consumption and cost estimates and compare them with actual figures.

Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development

PubMed Central

Tomar, Dheeraj S.; Kumar, Sandeep; Singh, Satish K.; Goswami, Sumit; Li, Li

2016-01-01

ABSTRACT Effective translation of breakthrough discoveries into innovative products in the clinic requires proactive mitigation or elimination of several drug development challenges. These challenges can vary depending upon the type of drug molecule. In the case of therapeutic antibody candidates, a commonly encountered challenge is high viscosity of the concentrated antibody solutions. Concentration-dependent viscosity behaviors of mAbs and other biologic entities may depend on pairwise and higher-order intermolecular interactions, non-native aggregation, and concentration-dependent fluctuations of various antibody regions. This article reviews our current understanding of molecular origins of viscosity behaviors of antibody solutions. We discuss general strategies and guidelines to select low viscosity candidates or optimize lead candidates for lower viscosity at early drug discovery stages. Moreover, strategies for formulation optimization and excipient design are also presented for candidates already in advanced product development stages. Potential future directions for research in this field are also explored. PMID:26736022

Computer-based guidelines for concrete pavements : volume III, technical appendices.

DOT National Transportation Integrated Search

2006-01-01

This report documents enhancements incorporated in the (HIgh PERformance PAVing) HIPERPAV II software. Enhancements made : within this project include the addition of two major modules: a module to predict the performance of JPCP as affected by early...

Menus and mnemonics in airway facilities.

DOT National Transportation Integrated Search

2003-04-01

This study examines the use of menus and mnemonics in current Airway Facilities (AF) systems and compares them to human factors : guidelines and best practices. Researchers from the William J. Hughes Technical Center traveled to AF field sites and co...

40 CFR 30.54 - Quality assurance.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER... Guidelines for Quality Systems for Environmental Data Collection and Environmental Technology Programs”, which may be obtained from the National Technical Information Service (NTIS), 5885 Port Royal Road...

40 CFR 30.54 - Quality assurance.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER... Guidelines for Quality Systems for Environmental Data Collection and Environmental Technology Programs”, which may be obtained from the National Technical Information Service (NTIS), 5885 Port Royal Road...

40 CFR 30.54 - Quality assurance.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER... Guidelines for Quality Systems for Environmental Data Collection and Environmental Technology Programs”, which may be obtained from the National Technical Information Service (NTIS), 5885 Port Royal Road...

40 CFR 30.54 - Quality assurance.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER... Guidelines for Quality Systems for Environmental Data Collection and Environmental Technology Programs”, which may be obtained from the National Technical Information Service (NTIS), 5885 Port Royal Road...

Guidelines to group practice. Fédération Dentaire Internationale. Technical Report No. 22.

PubMed

1985-09-01

This report reviews the types of group practice, the essential financial arrangements and the management procedures involved. The advantages and disadvantages of group practice to the dentist and the patient are reviewed.

46 CFR Appendix B to Subpart C of... - Substance Technical Guidelines, Benzene

Code of Federal Regulations, 2012 CFR

2012-10-01

...) Extinguishing media: Carbon dioxide, dry chemical, or foam. (5) Special fire fighting procedures: Do not use a... ignited by open flames or sparks at locations remote from the site at which benzene is handled. (7...

46 CFR Appendix B to Subpart C to... - Substance Technical Guidelines, Benzene

Code of Federal Regulations, 2011 CFR

2011-10-01

...) Extinguishing media: Carbon dioxide, dry chemical, or foam. (5) Special fire fighting procedures: Do not use a... ignited by open flames or sparks at locations remote from the site at which benzene is handled. (7...

46 CFR Appendix B to Subpart C of... - Substance Technical Guidelines, Benzene

Code of Federal Regulations, 2014 CFR

2014-10-01

...) Extinguishing media: Carbon dioxide, dry chemical, or foam. (5) Special fire fighting procedures: Do not use a... ignited by open flames or sparks at locations remote from the site at which benzene is handled. (7...

Wood tie track resistance characterization and correlations study

DOT National Transportation Integrated Search

1995-01-01

The work presented here is part of a major program to evaluate lateral buckling of continuous welded rail (CWR) tracks. The program to develop the technical information to support safety guidelines and specifications for track buckling prevention is ...

Gravel road paving guidelines, technical summary.

DOT National Transportation Integrated Search

2016-11-01

The percentage of gravel roads in rural areas in Kansas is higher than most states. A wide variation of traffic volumes across different regions and variations of local conditions and scenarios present a great challenge for local agencies to determin...

Cost-effective management of women with minor cervical lesions: Revisiting the application of HPV DNA testing.

PubMed

Pedersen, Kine; Burger, Emily A; Sy, Stephen; Kristiansen, Ivar S; Kim, Jane J

2016-11-01

Lack of consensus in management guidelines for women with minor cervical lesions, coupled with novel screening approaches, such as human papillomavirus (HPV) genotyping, necessitate revisiting prevention policies. We evaluated the cost-effectiveness and resource trade-offs of alternative triage strategies to inform cervical cancer prevention in Norway. We used a decision-analytic model to compare the lifetime health and economic consequences associated with ten novel candidate approaches to triage women with minor cervical lesions. Candidate strategies varied by: 1) the triage test(s): HPV testing in combination with cytology, HPV testing alone with or without genotyping for HPV-16 and -18, and immediate colposcopy, and 2) the length of time between index and triage testing (i.e., 6, 12 or 18months). Model outcomes included quality-adjusted life-years (QALYs), lifetime societal costs, and resource use (e.g., colposcopy referrals). The current Norwegian guidelines were less effective and more costly than candidate strategies. Given a commonly-cited willingness-to-pay threshold in Norway of $100,000 per QALY gained, the preferred strategy involved HPV genotyping with immediate colposcopy referral for HPV-16 or -18 positive and repeat HPV testing at 12months for non-HPV-16 or -18 positive ($78,010 per QALY gained). Differences in health benefits among candidate strategies were small, while resource use varied substantially. More effective strategies required a moderate increase in colposcopy referrals (e.g., a 9% increase for the preferred strategy) compared with current levels. New applications of HPV testing may improve management of women with minor cervical lesions, yet are accompanied by a trade-off of increased follow-up procedures. Copyright © 2016 Elsevier Inc. All rights reserved.

Cost-effective management of women with minor cervical lesions: Revisiting the application of HPV DNA testing

PubMed Central

Pedersen, Kine; Burger, Emily A.; Sy, Stephen; Kristiansen, Ivar S.; Kim, Jane J.

2016-01-01

Background Lack of consensus in management guidelines for women with minor cervical lesions, coupled with novel screening approaches, such as human papillomavirus (HPV) genotyping, necessitate revisiting prevention policies. We evaluated the cost-effectiveness and resource trade-offs of alternative triage strategies to inform cervical cancer prevention in Norway. Methods We used a decision-analytic model to compare the lifetime health and economic consequences associated with ten novel candidate approaches to triage women with minor cervical lesions. Candidate strategies varied by: 1) the triage test(s): HPV testing in combination with cytology, HPV testing alone with or without genotyping for HPV-16 and-18, and immediate colposcopy, and 2) the length of time between index and triage testing (i.e., 6, 12 or 18 months). Model outcomes included quality-adjusted life-years (QALYs), lifetime societal costs, and resource use (e.g., colposcopy referrals). Results The current Norwegian guidelines were less effective and more costly than candidate strategies. Given a commonly-cited willingness-to-pay threshold in Norway of $100,000 per QALY gained, the preferred strategy involved HPV genotyping with immediate colposcopy referral for HPV-16 or -18 positive and repeat HPV testing at 12 months for non-HPV-16 or -18 positive ($78,010 per QALY gained). Differences in health benefits among candidate strategies were small, while resource use varied substantially. More effective strategies required a moderate increase in colposcopy referrals (e.g., a 9% increase for the preferred strategy) compared with current levels. Conclusion New applications of HPV testing may improve management for women with minor cervical lesions, yet are accompanied by a trade-off of increased follow-up procedures. PMID:27542966

Case studies on clinical evaluation of biosimilar monoclonal antibody: scientific considerations for regulatory approval.

PubMed

Kudrin, Alex; Knezevic, Ivana; Joung, Jeewon; Kang, Hye-Na

2015-01-01

The objective of this paper is to provide considerations based on comprehensive case studies important for regulatory evaluation of monoclonal antibodies as similar biotherapeutic products (SBPs) with a special emphasis on clinical aspects. Scientific principles from WHO Guidelines on SBPs were used as a basis for the exercise. Working groups consisted of regulators, manufacturers and academia. The following topics were discussed by the working groups: clinical criteria for biosimilarity, extrapolation approach and the overall regulatory decision making process. In order to determine typical pitfalls in the design of a SBP clinical programme and evaluate the gap of knowledge, amongst different industry and regulatory stakeholders on the appraisal of the data arising from SBP clinical studies, we have presented two fictional but realistic clinical case studies. The first case consists of the fictional development programme for an infliximab SBP candidate. The second case describes clinical studies proposed for a fictional rituximab SBP candidate. In the first scenario a highly similar quality profile has been taken forward into clinical studies whereas there was an important residual difference in functional attributes for the rituximab SBP candidate. These case studies were presented at the WHO implementation workshop for the WHO guidelines on evaluation of similar biotherapeutic products held in Seoul, Republic of Korea, in May 2014. The goal was to illustrate the interpretation of the clinical data arising from studies with SBP candidates and elicit knowledge gaps in clinical assessment. This paper reflects the outcome of the exercise and discussions held in Seoul and offers an analysis of the case studies as a learning opportunity on clinical development and evaluation of SBPs. Copyright © 2014 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

Assessment of the technology required to develop photovoltaic power system for large scale national energy applications

NASA Technical Reports Server (NTRS)

Lutwack, R.

1974-01-01

A technical assessment of a program to develop photovoltaic power system technology for large-scale national energy applications was made by analyzing and judging the alternative candidate photovoltaic systems and development tasks. A program plan was constructed based on achieving the 10 year objective of a program to establish the practicability of large-scale terrestrial power installations using photovoltaic conversion arrays costing less than $0.50/peak W. Guidelines for the tasks of a 5 year program were derived from a set of 5 year objectives deduced from the 10 year objective. This report indicates the need for an early emphasis on the development of the single-crystal Si photovoltaic system for commercial utilization; a production goal of 5 x 10 to the 8th power peak W/year of $0.50 cells was projected for the year 1985. The developments of other photovoltaic conversion systems were assigned to longer range development roles. The status of the technology developments and the applicability of solar arrays in particular power installations, ranging from houses to central power plants, was scheduled to be verified in a series of demonstration projects. The budget recommended for the first 5 year phase of the program is $268.5M.

NASA preferred reliability-practices for design and test

NASA Technical Reports Server (NTRS)

Lisk, Ronald C.

1992-01-01

NASA HQ established the NASA R&M Steering Committee (R&MSC) comprised of membership from each NASA field center. The primary charter of the R&MSC is to obtain, record, and share the best design practices that NASA has applied to successful space flight programs and current design considerations (guidelines) that should enhance flight reliability on emerging programs. The practices and guidelines are being assembled in a living document for distribution to NASA centers and the aerospace community. The document will be updated annually with additional practices and guidelines as contributions from the centers are reviewed and approved by the R&MSC. Practices and guidelines are not requirements, but rather a means of sharing procedures and techniques that a given center and the R&MSC together feel have strong technical merit and application to the design of space-related equipment.

Hydrogen turbine power conversion system assessment

NASA Technical Reports Server (NTRS)

Wright, D. E.; Lucci, A. D.; Campbell, J.; Lee, J. C.

1978-01-01

A three part technical study was conducted whereby parametric technical and economic feasibility data were developed on several power conversion systems suitable for the generation of central station electric power through the combustion of hydrogen and the use of the resulting heat energy in turbogenerator equipment. The study assessed potential applications of hydrogen-fueled power conversion systems and identified the three most promising candidates: (1) Ericsson Cycle, (2) gas turbine, and (3) direct steam injection system for fossil fuel as well as nuclear powerplants. A technical and economic evaluation was performed on the three systems from which the direct injection system (fossil fuel only) was selected for a preliminary conceptual design of an integrated hydrogen-fired power conversion system.

Impact of the New ACC/AHA Guidelines on the Treatment of High Blood Cholesterol in a Managed Care Setting.

PubMed

Tran, Josephine N; Caglar, Toros; Stockl, Karen M; Lew, Heidi C; Solow, Brian K; Chan, Paul S

2014-11-01

In November 2013, the American College of Cardiology (ACC) and the American Heart Association (AHA) together issued new guidelines for the treatment of patients with high cholesterol, providing a new paradigm for the management of cholesterol in the primary and secondary prevention of coronary artery disease. To examine the impact of the 2013 ACC/AHA cholesterol treatment guidelines on pharmacy utilization of cholesterol-lowering drugs in a real-world managed care setting. Pharmacy claims from OptumRx, a national pharmacy benefit management provider, for the period between January 1, 2013, and December 31, 2013 (baseline period), were used to identify candidates for cholesterol-lowering therapy and to estimate the number of potential patients who will be starting or intensifying statin therapy based on the updated cholesterol treatment guidelines. Potential candidates for cholesterol-lowering treatments included patients with diabetes or hypertension aged 40 to 75 years who were not already receiving a cholesterol-lowering medication, as well as patients receiving cholesterol-lowering therapies during the baseline period. The baseline cholesterol-lowering medication market share was used to project changes in pharmacy utilization over the next 3 years. Based on the 2013 ACC/AHA cholesterol treatment guidelines, there will be a 25% increase in the proportion of the overall population that is treated with statins over the next 3 years, increasing from 3,909,407 (27.7%) patients to 4,892,668 (34.7%) patients. The largest proportion of the increase in statin utilization is projected to be for primary prevention in patients aged 40 to 75 years who were not receiving any cholesterol-lowering treatment at baseline. These projected changes will increase the overall number of statin prescriptions by 25% and will decrease the number of nonstatin cholesterol-lowering medication prescriptions by 68% during the next 3 years. The new 2013 ACC/AHA cholesterol treatment guidelines are projected to have a significant impact on the utilization of cholesterol-lowering drugs by increasing the overall proportion of the population receiving statin therapy and by decreasing the utilization of nonstatin cholesterol-lowering medications.

Technical assessment of satellites for CONUS air traffic control Volume III: satellite-to-aircraft techniques

DOT National Transportation Integrated Search

1974-02-17

A number of satellite system techniques have been suggested as candidates to provide ATC surveillance, communication, and/or navigation service over CONUS. All techniques determine the aircraft positions by multilateration based on the arrival times ...

Unions, Contractors and CTE

ERIC Educational Resources Information Center

Jarosz, Francesca

2006-01-01

Across Illinois, in places where unions thrive, construction industry professionals and career and technical education (CTE) teachers are working together in promoting work-based learning program to students. Likewise, the outreach program provides union-supported contractors with qualified candidates for future employment. Programs such as the…

Simulation as an ethical imperative and epistemic responsibility for the implementation of medical guidelines in health care.

PubMed

Garbayo, Luciana; Stahl, James

2017-03-01

Guidelines orient best practices in medicine, yet, in health care, many real world constraints limit their optimal realization. Since guideline implementation problems are not systematically anticipated, they will be discovered only post facto, in a learning curve period, while the already implemented guideline is tweaked, debugged and adapted. This learning process comes with costs to human health and quality of life. Despite such predictable hazard, the study and modeling of medical guideline implementation is still seldom pursued. In this article we argue that to systematically identify, predict and prevent medical guideline implementation errors is both an epistemic responsibility and an ethical imperative in health care, in order to properly provide beneficence, minimize or avoid harm, show respect for persons, and administer justice. Furthermore, we suggest that implementation knowledge is best achieved technically by providing simulation modeling studies to anticipate the realization of medical guidelines, in multiple contexts, with system and scenario analysis, in its alignment with the emerging field of implementation science and in recognition of learning health systems. It follows from both claims that it is an ethical imperative and an epistemic responsibility to simulate medical guidelines in context to minimize (avoidable) harm in health care, before guideline implementation.

Technical basis for nuclear accident dosimetry at the Oak Ridge National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kerr, G.D.; Mei, G.T.

The Oak Ridge National Laboratory (ORNL) Environmental, Safety, and Health Emergency Response Organization has the responsibility of providing analyses of personnel exposures to neutrons and gamma rays from a nuclear accident. This report presents the technical and philosophical basis for the dose assessment aspects of the nuclear accident dosimetry (NAD) system at ORNL. The issues addressed are regulatory guidelines, ORNL NAD system components and performance, and the interpretation of dosimetric information that would be gathered following a nuclear accident.

Fingerprinting of Materials: Technical Supplement

NASA Technical Reports Server (NTRS)

Workman, Gary L.

1992-01-01

This supplement to the Guidelines for Maintaining a Chemical Fingerprinting Program has been developed to assist NASA personnel, contractors, and sub-contractors in defining the technical aspects and basic concepts which can be used in chemical fingerprinting programs. This material is not meant to be totally inclusive to all chemical fingerprinting programs, but merely to present current concepts. Each program will be tailored to meet the needs of the individual organizations using chemical fingerprinting to improve their quality and reliability in the production of aerospace systems.

A Comparative Discourse Analysis of Spanish Past Narrations from the ACTFL OPI and OPIc

ERIC Educational Resources Information Center

Brown, Alan V.; Cox, Troy L.; Thompson, Gregory L.

2017-01-01

The ACTFL Oral Proficiency Interview (OPI) and accompanying proficiency guidelines have become a mainstay in academic foreign language assessment. In 2006, an asynchronous electronic interface of the OPI was made available in which candidates are asked to record themselves responding to questions delivered aurally via computer, labeled the Oral…

10 CFR 960.3-2-3 - Recommendation of sites for characterization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Recommendation of sites for characterization. 960.3-2-3... POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-3 Recommendation of sites... President not less than three candidate sites for such characterization. The recommendation decision shall...

10 CFR 960.3-1-4-3 - Site recommendation for characterization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Site recommendation for characterization. 960.3-1-4-3... POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-3 Site recommendation for characterization. The evidence required to support the recommendation of a site as a candidate...

Utilization of Radiographs for a State Dental Hygiene Board Examination.

ERIC Educational Resources Information Center

Potter, Brad G.; And Others

1993-01-01

A study documented the number of x-rays acquired during screening and subsequent treatment of patients for a state dental hygiene licensing examination for 109 candidates. Results indicate that patient exposure guidelines attempt to minimize radiographic exposure but that some exposures should be reevaluated for need and effect on patients. (MSE)

Development of human factors guidelines for advanced traveler information systems and commercial vehicle operations : definition and prioritization of research studies

DOT National Transportation Integrated Search

1997-03-01

The goal of the activities documented in this report was to produce a prioritized list of candidate studies and issues that would guide data acquisition in this project. This goal was accomplished in three steps. First, 91 issues were compiled from e...

Learner Diary Research with "Cambridge" Examination Candidates.

ERIC Educational Resources Information Center

Parkinson, Brian; Benson, Cathy; Jenkins, Michael

2003-01-01

This paper describes a research project in which volunteers, self-selected from IALS students preparing for one or more of the Cambridge English Examinations, kept journals. Following guidelines, they reflected on their in-class and outside-of-class experiences in the 8 weeks leading up to the exams. They also attended four biweekly meetings with…

Appropriate selection for omalizumab treatment in patients with severe asthma?

PubMed

Nygaard, Leo; Henriksen, Daniel Pilsgaard; Madsen, Hanne; Davidsen, Jesper Rømhild

2017-01-01

Background : Omalizumab improves asthma control in patients with uncontrolled severe allergic asthma; however, appropriate patient selection is crucial. Information in this field is sparse. Objective : We aimed to estimate whether potential omalizumab candidates were appropriately selected according to guidelines, and the clinical effect of omalizumab treatment over time. Design : We performed a retrospective observational study on adult patients with asthma treated with omalizumab during 2006-2015 at the Department of Respiratory Medicine at Odense University Hospital (OUH), Denmark. Data were obtained from the Electronic Patient Journal of OUH and Odense Pharmaco-Epidemiological Database. Guideline criteria for omalizumab treatment were used to evaluate the appropriateness of omalizumab candidate selection, and the Asthma Control Test (ACT) to assess the clinical effects of omalizumab at weeks 16 and 52 from treatment initiation. Results : During the observation period, 24 patients received omalizumab, but only 10 patients (42%) fulfilled criteria recommended by international guidelines. The main reasons for not fulfilling the criteria were inadequately reduced lung function, insufficient number of exacerbations, and asthma standard therapy below Global Initiative for Asthma (GINA) step 4-5. Seventeen and 11 patients completed treatment at weeks 16 and 52, with a statistically significant increase in ACT score of 5.1 points [95% confidence interval (CI) 3.1-7.2, p  = 0.0001] and 7.7 points (95% CI 4.3-11.1, p  = 0.0005), respectively. Conclusion : Only 42% of the omalizumab-treated patients were appropriately selected according to current guidelines. Still, as omalizumab showed significant improvement in asthma control over time, it is important to keep this drug in mind as an add-on to asthma therapy in well-selected patients.

Appropriate selection for omalizumab treatment in patients with severe asthma?

PubMed Central

Nygaard, Leo; Henriksen, Daniel Pilsgaard; Madsen, Hanne; Davidsen, Jesper Rømhild

2017-01-01

ABSTRACT Background: Omalizumab improves asthma control in patients with uncontrolled severe allergic asthma; however, appropriate patient selection is crucial. Information in this field is sparse. Objective: We aimed to estimate whether potential omalizumab candidates were appropriately selected according to guidelines, and the clinical effect of omalizumab treatment over time. Design: We performed a retrospective observational study on adult patients with asthma treated with omalizumab during 2006–2015 at the Department of Respiratory Medicine at Odense University Hospital (OUH), Denmark. Data were obtained from the Electronic Patient Journal of OUH and Odense Pharmaco-Epidemiological Database. Guideline criteria for omalizumab treatment were used to evaluate the appropriateness of omalizumab candidate selection, and the Asthma Control Test (ACT) to assess the clinical effects of omalizumab at weeks 16 and 52 from treatment initiation. Results: During the observation period, 24 patients received omalizumab, but only 10 patients (42%) fulfilled criteria recommended by international guidelines. The main reasons for not fulfilling the criteria were inadequately reduced lung function, insufficient number of exacerbations, and asthma standard therapy below Global Initiative for Asthma (GINA) step 4–5. Seventeen and 11 patients completed treatment at weeks 16 and 52, with a statistically significant increase in ACT score of 5.1 points [95% confidence interval (CI) 3.1–7.2, p = 0.0001] and 7.7 points (95% CI 4.3–11.1, p = 0.0005), respectively. Conclusion: Only 42% of the omalizumab-treated patients were appropriately selected according to current guidelines. Still, as omalizumab showed significant improvement in asthma control over time, it is important to keep this drug in mind as an add-on to asthma therapy in well-selected patients. PMID:28815007

Transitioning to HIV Pre-Exposure Prophylaxis (PrEP) from Non-Occupational Post-Exposure Prophylaxis (nPEP) in a Comprehensive HIV Prevention Clinic: A Prospective Cohort Study.

PubMed

Siemieniuk, Reed A C; Sivachandran, Nirojini; Murphy, Pauline; Sharp, Andrea; Walach, Christine; Placido, Tania; Bogoch, Isaac I

2015-08-01

The uptake of pre-exposure prophylaxis (PrEP) for HIV prevention remains low. We hypothesized that a high proportion of patients presenting for HIV non-occupational post-exposure prophylaxis (nPEP) would be candidates for PrEP based on current CDC guidelines. Outcomes from a comprehensive HIV Prevention Clinic are described. We evaluated all patients who attended the HIV Prevention Clinic for nPEP between January 1, 2013 and September 30, 2014. Each patient was evaluated for PrEP candidacy based on current CDC-guidelines and subjectively based on physician opinion. Patients were then evaluated for initiation of PrEP if they met guideline suggestions. Demographic, social, and behavioral factors were then analyzed with logistic regression for associations with PrEP candidacy and initiation. 99 individuals who attended the nPEP clinic were evaluated for PrEP. The average age was 32 years (range, 18-62), 83 (84%) were male, of whom 46 (55%) men who had have sex with men (MSM). 31 (31%) met CDC guidelines for PrEP initiation, which had very good agreement with physician recommendation (kappa=0.88, 0.78-0.98). Factors associated with PrEP candidacy included sexual exposure to HIV, prior nPEP use, and lack of drug insurance (p<0.05 for all comparisons). Combining nPEP and PrEP services in a dedicated clinic can lead to identification of PrEP candidates and may facilitate PrEP uptake. Strategies to ensure equitable access of PrEP should be explored such that those without drug coverage may also benefit from this effective HIV prevention modality.

7 CFR 2812.2 - Eligibility.

Code of Federal Regulations, 2013 CFR

2013-01-01

... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i) § 2812.2 Eligibility. Eligible organizations are educational institutions or non-profit organizations involved in the conduct of technical and scientific educational and research activities. ...

7 CFR 2812.2 - Eligibility.

Code of Federal Regulations, 2012 CFR

2012-01-01

... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i) § 2812.2 Eligibility. Eligible organizations are educational institutions or non-profit organizations involved in the conduct of technical and scientific educational and research activities. ...

7 CFR 2812.2 - Eligibility.

Code of Federal Regulations, 2014 CFR

2014-01-01

... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i) § 2812.2 Eligibility. Eligible organizations are educational institutions or non-profit organizations involved in the conduct of technical and scientific educational and research activities. ...

7 CFR 2812.2 - Eligibility.

Code of Federal Regulations, 2011 CFR

2011-01-01

... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i) § 2812.2 Eligibility. Eligible organizations are educational institutions or non-profit organizations involved in the conduct of technical and scientific educational and research activities. ...

7 CFR 1944.510 - Applicant eligibility.

Code of Federal Regulations, 2011 CFR

2011-01-01

...-income rural families; (e) Have the ability and willingness to work within established guidelines; and (f... capacity, it must either: (1) Have necessary background and experience with proven ability to perform... or administrative experience which indicates an ability to provide responsible technical and...

7 CFR 1944.510 - Applicant eligibility.

Code of Federal Regulations, 2012 CFR

2012-01-01

...-income rural families; (e) Have the ability and willingness to work within established guidelines; and (f... capacity, it must either: (1) Have necessary background and experience with proven ability to perform... or administrative experience which indicates an ability to provide responsible technical and...

Capabilities and limitations of nondestructive evaluation methods for inspecting components beneath thermal protection systems

DOT National Transportation Integrated Search

2004-07-30

The Aerospace Corporation was tasked by the Volpe National Transportation Systems Center to provide technical support to the Federal Aviation Administration, Office of Commercial Space Transportation (FAA/AST), to develop guidelines for inspecting co...

[Using new media for online consensus conferences and open external review of guidelines - results of two pilot studies].

PubMed

Nast, Alexander; Rosumeck, Stefanie; Sporbeck, Birte; Rzany, Berthold

2012-01-01

The development of guidelines almost always requires considerable time and financial resources. An important task is therefore to identify and evaluate online methods that facilitate guideline work. ONLINE CONSENSUS CONFERENCE: During the development of the S2k guideline for the management of staphylococcus aureus infections an online consensus conference was held using an online tool provided by the Deutsche Forschungsnetz in combination with a telephone conference. During the 2-hour meeting, no technical difficulties occurred. A survey among the participants showed that this format had a high rate of acceptance. ONLINE REVIEW: During the development of the update of the German S3-Guidelines for the therapy of psoriasis an external open review was performed. An online platform allowing direct visible commenting was chosen. During the five week period of commenting, 26 users added 160 comments. After the review process, the comments were assessed by the editors and the original authors. The selected instrument provides a suitable means for online commenting of guidelines and facilitates the revision of the text. Copyright © 2012. Published by Elsevier GmbH.

The importance of morphometric radiographic vertebral assessment for the detection of patients who need pharmacological treatment of osteoporosis among postmenopausal diabetic Korean women.

PubMed

Choi, Y J; Yang, S-O; Shin, C S; Chung, Y-S

2012-08-01

Many diabetic patients with vertebral fractures remain undiagnosed and untreated. We found that more than two-thirds of osteoporotic diabetic women could not be identified for pharmacological treatment according to the NOF guidelines if without radiographic vertebral assessment. This study shows the importance of radiographic vertebral assessment for identifying patients who need treatment for osteoporosis in diabetic women. Diagnosis of vertebral fracture (VF) is important for identifying patients who need pharmacologic therapy for osteoporosis. However, many patients with vertebral fractures remain undiagnosed and untreated. This study evaluated the number of patients with VFs who would be unrecognized as candidates for osteoporosis treatments according to the National Osteoporosis Foundation (NOF) Clinician’s Guidelines to the Treatment of Osteoporosis, among postmenopausal diabetic Korean women without spinal imaging. A total of 873 postmenopausal diabetic women were enrolled. Lateral plain radiographs of the thoracolumbar spine and total hip BMD were obtained. The Fracture Risk Assessment Tool (FRAX®) probability was computed using the algorithm available online at http://www.shef.ac.uk/FRAX (South Korea version). The subjects with and without VFs were classified into candidates for osteoporosis treatment [Tx+by NOF] and not candidates for osteoporosis treatment [Tx−by NOF] according to the NOF pharmacologic treatment guidelines, regardless of the presence of VFs. Forty-six percent of postmenopausal diabetic womenhad morphometric VFs. Among the subjects with morphometric VFs, only 2% of the patients had previously diagnosed VFs by medical doctors. In addition, 73.6% of the patients with VFs were not included in the [Tx+by NOF] group, given the assumption of no radiographic diagnosis of VFs. With regard to increased risk of VFs in postmenopausal Korean women with type 2 diabetes mellitus, radiographic vertebral assessment would be useful for the clinical identification of osteoporosis and fractures.

Landfill Gas Energy Project Data and Landfill Technical Data

EPA Pesticide Factsheets

This page provides data from the LMOP Database for U.S. landfills and LFG energy projects in Excel files, a map of project and candidate landfill counts by state, project profiles for a select group of projects, and information about Project Expo sites.

Power system requirements and definition for lunar and Mars outposts

NASA Technical Reports Server (NTRS)

Petri, D. A.; Cataldo, R. L.; Bozek, J. M.

1990-01-01

Candidate power systems being considered for outpost facilities (stationary power systems) and vehicles (mobile systems) are discussed, including solar, chemical, isotopic, and reactor. The current power strategy was an initial outpost power system composed of photovoltaic arrays for daytime energy needs and regenerative fuel cells for power during the long lunar night. As day and night power demands grow, the outpost transitions to nuclear-based power generation, using thermoelectric conversion initially and evolving to a dynamic conversion system. With this concept as a guideline, a set of requirements has been established, and a reference definition of candidate power systems meeting these requirements has been identified.

Experiment Definition Using the Space Laboratory, Long Duration Exposure Facility, and Space Transportation System Shuttle

NASA Technical Reports Server (NTRS)

Sheppard, Albert P.; Wood, Joan M.

1976-01-01

Candidate experiments designed for the space shuttle transportation system and the long duration exposure facility are summarized. The data format covers: experiment title, Experimenter, technical abstract, benefits/justification, technical discussion of experiment approach and objectives, related work and experience, experiment facts space properties used, environmental constraints, shielding requirements, if any, physical description, and sketch of major elements. Information was also included on experiment hardware, research required to develop experiment, special requirements, cost estimate, safety considerations, and interactions with spacecraft and other experiments.

Comparison of the quality of basic life support provided by rescuers trained using the 2005 or 2010 ERC guidelines.

PubMed

Jones, Christopher M; Owen, Andrew; Thorne, Christopher J; Hulme, Jonathan

2012-08-09

Effective delivery of cardiopulmonary resuscitation (CPR) and prompt defibrillation following sudden cardiac arrest (SCA) is vital. Updated guidelines for adult basic life support (BLS) were published in 2010 by the European Resuscitation Council (ERC) in an effort to improve survival following SCA. There has been little assessment of the ability of rescuers to meet the standards outlined within these new guidelines. We conducted a retrospective analysis of the performance of first year healthcare students trained and assessed using either the new 2010 ERC guidelines or their 2005 predecessor, within the University of Birmingham, United Kingdom. All students were trained as lay rescuers during a standardised eight hour ERC-accredited adult BLS course. We analysed the examination records of 1091 students. Of these, 561 were trained and assessed using the old 2005 ERC guidelines and 530 using the new 2010 guidelines. A significantly greater proportion of candidates failed in the new guideline group (16.04% vs. 11.05%; p < 0.05), reflecting a significantly greater proportion of lay-rescuers performing chest compressions at too fast a rate when trained and assessed with the 2010 rather than 2005 guidelines (6.04% vs. 2.67%; p < 0.05). Error rates for other skills did not differ between guideline groups. The new ERC guidelines lead to a greater proportion of lay rescuers performing chest compressions at an erroneously fast rate and may therefore worsen BLS efficacy. Additional study is required in order to define the clinical impact of compressions performed to a greater depth and at too fast a rate.

Guidelines on iron chelation therapy in patients with myelodysplastic syndromes and transfusional iron overload.

PubMed

Gattermann, Norbert

2007-12-01

Experts believe that iron overload is an important problem which could be avoided with suitable treatment. Guidelines on treating myelodysplastic syndromes (MDS) include sections on using iron chelation therapy to prevent or ameliorate transfusional iron overload. The proportion of MDS patients who may benefit from iron chelation therapy is 35-55%, depending on the length of survival necessary for iron to accumulate to a detrimental level. Candidates for iron chelation are mainly patients with dyserythropoietic and cytopenic subtypes of disease, which fall into the International Prognostic Scoring System (IPSS) Low-risk or Intermediate-1-risk categories, with median survival of 3-6 years.

Evaluating Nextgen Closely Spaced Parallel Operations Concepts with Validated Human Performance Models: Flight Deck Guidelines

NASA Technical Reports Server (NTRS)

Hooey, Becky Lee; Gore, Brian Francis; Mahlstedt, Eric; Foyle, David C.

2013-01-01

The objectives of the current research were to develop valid human performance models (HPMs) of approach and land operations; use these models to evaluate the impact of NextGen Closely Spaced Parallel Operations (CSPO) on pilot performance; and draw conclusions regarding flight deck display design and pilot-ATC roles and responsibilities for NextGen CSPO concepts. This document presents guidelines and implications for flight deck display designs and candidate roles and responsibilities. A companion document (Gore, Hooey, Mahlstedt, & Foyle, 2013) provides complete scenario descriptions and results including predictions of pilot workload, visual attention and time to detect off-nominal events.

Adapting clinical practice guidelines for diabetic retinopathy in Kenya: process and outputs.

PubMed

Mwangi, Nyawira; Gachago, Muchai; Gichangi, Michael; Gichuhi, Stephen; Githeko, Kibata; Jalango, Atieno; Karimurio, Jefitha; Kibachio, Joseph; Muthami, Lawrence; Ngugi, Nancy; Nduri, Carmichael; Nyaga, Patrick; Nyamori, Joseph; Zindamoyen, Alain Nazaire Mbongo; Bascaran, Covadonga; Foster, Allen

2018-06-15

The use of clinical practice guidelines envisages augmenting quality and best practice in clinical outcomes. Generic guidelines that are not adapted for local use often fail to produce these outcomes. Adaptation is a systematic and rigorous process that should maintain the quality and validity of the guideline, while making it more usable by the targeted users. Diverse skills are required for the task of adaptation. Although adapting a guideline is not a guarantee that it will be implemented, adaptation may improve acceptance and adherence to its recommendations. We describe the process used to adapt clinical guidelines for diabetic retinopathy in Kenya, using validated tools and manuals. A technical working group consisting of volunteers provided leadership. The process was intensive and required more time than anticipated. Flexibility in the process and concurrent health system activities contributed to the success of the adaptation. The outputs from the adaptation include the guidelines in different formats, point of care instruments, as well as tools for training, monitoring, quality assurance and patient education. Guideline adaptation is applicable and feasible at the national level in Kenya. However, it is labor- and time -intensive. It presents a valuable opportunity to develop several additional outputs that are useful at the point of care.

GSFC Ada programming guidelines

NASA Technical Reports Server (NTRS)

Roy, Daniel M.; Nelson, Robert W.

1986-01-01

A significant Ada effort has been under way at Goddard for the last two years. To ease the center's transition toward Ada (notably for future space station projects), a cooperative effort of half a dozen companies and NASA personnel was started in 1985 to produce programming standards and guidelines for the Ada language. The great richness of the Ada language and the need of programmers for good style examples makes Ada programming guidelines an important tool to smooth the Ada transition. Because of the natural divergence of technical opinions, the great diversity of our government and private organizations and the novelty of the Ada technology, the creation of an Ada programming guidelines document is a difficult and time consuming task. It is also a vital one. Steps must now be taken to ensure that the guide is refined in an organized but timely manner to reflect the growing level of expertise of the Ada community.

Evaluation of exposure parameters in plain radiography: a comparative study with European guidelines.

PubMed

Lança, L; Silva, A; Alves, E; Serranheira, F; Correia, M

2008-01-01

Typical distribution of exposure parameters in plain radiography is unknown in Portugal. This study aims to identify exposure parameters that are being used in plain radiography in the Lisbon area and to compare the collected data with European references [Commission of European Communities (CEC) guidelines]. The results show that in four examinations (skull, chest, lumbar spine and pelvis), there is a strong tendency of using exposure times above the European recommendation. The X-ray tube potential values (in kV) are below the recommended values from CEC guidelines. This study shows that at a local level (Lisbon region), radiographic practice does not comply with CEC guidelines concerning exposure techniques. Further national/local studies are recommended with the objective to improve exposure optimisation and technical procedures in plain radiography. This study also suggests the need to establish national/local diagnostic reference levels and to proceed to effective measurements for exposure optimisation.

Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

PubMed

Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

2013-03-01

The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report.

PubMed

Wahidi, Momen M; Herth, Felix; Yasufuku, Kazuhiro; Shepherd, Ray Wesley; Yarmus, Lonny; Chawla, Mohit; Lamb, Carla; Casey, Kenneth R; Patel, Sheena; Silvestri, Gerard A; Feller-Kopman, David J

2016-03-01

Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lung masses. The many publications produced about EBUS-TBNA have led to a better understanding of the performance characteristics of this procedure. The goal of this document was to examine the current literature on the technical aspects of EBUS-TBNA as they relate to patient, technology, and proceduralist factors to provide evidence-based and expert guidance to clinicians. Rigorous methodology has been applied to provide a trustworthy evidence-based guideline and expert panel report. A group of approved panelists developed key clinical questions by using the PICO (population, intervention, comparator, and outcome) format that addressed specific topics on the technical aspects of EBUS-TBNA. MEDLINE (via PubMed) and the Cochrane Library were systematically searched for relevant literature, which was supplemented by manual searches. References were screened for inclusion, and well-recognized document evaluation tools were used to assess the quality of included studies, to extract meaningful data, and to grade the level of evidence to support each recommendation or suggestion. Our systematic review and critical analysis of the literature on 15 PICO questions related to the technical aspects of EBUS-TBNA resulted in 12 statements: 7 evidence-based graded recommendations and 5 ungraded consensus-based statements. Three questions did not have sufficient evidence to generate a statement. Evidence on the technical aspects of EBUS-TBNA varies in strength but is satisfactory in certain areas to guide clinicians on the best conditions to perform EBUS-guided tissue sampling. Additional research is needed to enhance our knowledge regarding the optimal performance of this effective procedure. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

Development of an improved overlay procedure for Oregon : volume III, field manual.

DOT National Transportation Integrated Search

1987-12-01

This report is the third in a three-volume series dealing with the development of an improved overlay design procedure for Oregon. This report presents technical guidelines for using the proposed overlay design procedure. Four areas are described, in...

40 CFR 243.100 - Scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... agency including technical data and policy considerations used in arriving at this decision. In covering... AND COLLECTION OF RESIDENTIAL, COMMERCIAL, AND INSTITUTIONAL SOLID WASTE General Provisions § 243.100... Disposal Act, as amended (Pub. L. 89-272). (b) The guidelines apply to the collection of residential...

Guidelines for Selecting Microphones for Human Voice Production Research

ERIC Educational Resources Information Center

Svec, Jan G.; Granqvist, Svante

2010-01-01

Purpose: This tutorial addresses fundamental characteristics of microphones (frequency response, frequency range, dynamic range, and directionality), which are important for accurate measurements of voice and speech. Method: Technical and voice literature was reviewed and analyzed. The following recommendations on desirable microphone…

Developing guidelines for repairing severe edge failures : technical report.

DOT National Transportation Integrated Search

2014-04-01

This report presents various edge failures, the methods used by districts to repair them, and the results of the : repair. While there was no clear consensus on the best treatment of in-situ material for pavements with edge : failures, the districts ...

40 CFR 52.2633 - Stack height regulations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Stack height regulations. 52.2633 Section 52.2633 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... with the “Guideline for Determination of Good Engineering Practice Stack Height (Technical Support...

43 CFR 11.18 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Values of Freshwater Fish and Fish-Kill Guidelines,” American Fisheries Society Special Publication... Type A Natural Resource Damage Assessment Model for Coastal and Marine Environments Technical... the U.S. Department of the Interior by Applied Science Associates, Inc., and Hagler Bailly Consulting...

43 CFR 11.18 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Values of Freshwater Fish and Fish-Kill Guidelines,” American Fisheries Society Special Publication... Type A Natural Resource Damage Assessment Model for Coastal and Marine Environments Technical... the U.S. Department of the Interior by Applied Science Associates, Inc., and Hagler Bailly Consulting...

43 CFR 11.18 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Values of Freshwater Fish and Fish-Kill Guidelines,” American Fisheries Society Special Publication... Type A Natural Resource Damage Assessment Model for Coastal and Marine Environments Technical... the U.S. Department of the Interior by Applied Science Associates, Inc., and Hagler Bailly Consulting...

43 CFR 11.18 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Values of Freshwater Fish and Fish-Kill Guidelines,” American Fisheries Society Special Publication... Type A Natural Resource Damage Assessment Model for Coastal and Marine Environments Technical... the U.S. Department of the Interior by Applied Science Associates, Inc., and Hagler Bailly Consulting...

43 CFR 11.18 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Values of Freshwater Fish and Fish-Kill Guidelines,” American Fisheries Society Special Publication... Type A Natural Resource Damage Assessment Model for Coastal and Marine Environments Technical... the U.S. Department of the Interior by Applied Science Associates, Inc., and Hagler Bailly Consulting...

76 FR 30229 - Shipping Coordinating Committee; Notice of Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

.... --Strategy and planning. --Organizational reforms. --Resource management. --Technical Co-operation Fund--biennial allocation to support the ITCP Programme for 2012-2013. --Results-based budget. --Voluntary IMO... FSS Code for communication equipment for fire-fighting teams. --Development of guidelines for use of...

Handbook for Public Playground Safety.

ERIC Educational Resources Information Center

Consumer Product Safety Commission, Washington, DC.

Playgrounds, being a fundamental part of the childhood experience, should be safe havens for children. This handbook includes technical safety guidelines for designing, constructing, operating, and maintaining public playgrounds. It also includes a "Public Playground Safety Checklist" to highlight some of the most important safety issues…

A very low number of national adaptations of the World Health Organization guidelines for HIV and tuberculosis reported their processes.

PubMed

Godah, Mohammad W; Abdul Khalek, Rima A; Kilzar, Lama; Zeid, Hiba; Nahlawi, Acile; Lopes, Luciane Cruz; Darzi, Andrea J; Schünemann, Holger J; Akl, Elie A

2016-12-01

Low- and middle-income countries adapt World Health Organization (WHO) guidelines instead of de novo development for financial, epidemiologic, sociopolitical, cultural, organizational, and other reasons. To systematically evaluate reported processes used in the adaptation of WHO guidelines for human immunodeficiency virus (HIV) and tuberculosis (TB). We searched three online databases/repositories: United States Agency for International Development (USAID) AIDS Support and Technical Resources - Sector One program (AIDSTAR-One) National Treatment Database; the AIDSspace Guideline Repository, and WHO Database of national HIV and TB guidelines. We assessed the rigor and quality of reported adaptation methodology using the ADAPTE process as benchmark. Of 170 eligible guidelines, only 32 (19%) reported documentation on the adaptation process. The median and interquartile range of the number of ADAPTE steps fulfilled by the eligible guidelines were 11.5 (10, 13.5) (out of 23 steps). The number of guidelines (out of 32 steps) fulfilling each ADAPTE step was 18 (interquartile range, 5-27). Seventeen of 32 guidelines (53%) met all steps relevant to the setup phase, whereas none met all steps relevant to the adaptation phase. The number of well-documented adaptation methodologies in national HIV and/or TB guidelines is very low. There is a need for the use of standardized and systematic framework for guideline adaptation and improved reporting of processes used. Copyright © 2016 Elsevier Inc. All rights reserved.

Quality Primary Care and Family Planning Services for LGBT Clients: A Comprehensive Review of Clinical Guidelines.

PubMed

Klein, David A; Malcolm, Nikita M; Berry-Bibee, Erin N; Paradise, Scott L; Coulter, Jessica S; Keglovitz Baker, Kristin; Schvey, Natasha A; Rollison, Julia M; Frederiksen, Brittni N

2018-04-01

LGBT clients have unique healthcare needs but experience a wide range of quality in the care that they receive. This study provides a summary of clinical guideline recommendations related to the provision of primary care and family planning services for LGBT clients. In addition, we identify gaps in current guidelines, and inform future recommendations and guidance for clinical practice and research. PubMed, Cochrane, and Agency for Healthcare Research and Quality electronic bibliographic databases, and relevant professional organizations' websites, were searched to identify clinical guidelines related to the provision of primary care and family planning services for LGBT clients. Information obtained from a technical expert panel was used to inform the review. Clinical guidelines meeting the inclusion criteria were assessed to determine their alignment with Institute of Medicine (IOM) standards for the development of clinical practice guidelines and content relevant to the identified themes. The search parameters identified 2,006 clinical practice guidelines. Seventeen clinical guidelines met the inclusion criteria. Two of the guidelines met all eight IOM criteria. However, many recommendations were consistent regarding provision of services to LGBT clients within the following themes: clinic environment, provider cultural sensitivity and awareness, communication, confidentiality, coordination of care, general clinical principles, mental health considerations, and reproductive health. Guidelines for the primary and family planning care of LGBT clients are evolving. The themes identified in this review may guide professional organizations during guideline development, clinicians when providing care, and researchers conducting LGBT-related studies.

Scaffolding the design of accessible eLearning content: a user-centered approach and cognitive perspective.

PubMed

Catarci, Tiziana; De Giovanni, Loredana; Gabrielli, Silvia; Kimani, Stephen; Mirabella, Valeria

2008-08-01

There exist various guidelines for facilitating the design, preparation, and deployment of accessible eLearning applications and contents. However, such guidelines prevalently address accessibility in a rather technical sense, without giving sufficient consideration to the cognitive aspects and issues related to the use of eLearning materials by learners with disabilities. In this paper we describe how a user-centered design process was applied to develop a method and set of guidelines for didactical experts to scaffold their creation of accessible eLearning content, based on a more sound approach to accessibility. The paper also discusses possible design solutions for tools supporting eLearning content authors in the adoption and application of the proposed approach.

Guidelines for Acoustical Measurements Inside Historical Opera Houses: Procedures and Validation

NASA Astrophysics Data System (ADS)

POMPOLI, ROBERTO; PRODI, NICOLA

2000-04-01

The acoustics of Italian historical theatres is to be regarded as a cultural heritage, which is to be preserved and studied. These actions are imperative for handing down the heritage to future generations and to avoid its loss. In this paper, the technical means for scientific quantification of the acoustical heritage are presented in the form of operative guidelines for acoustical measurements inside historical theatres. The document includes the advice of international experts and is being employed during an extended measurement campaign inside renaissance and baroque historical theatres. A relevant part of the paper deals with the experimental validation of the recommendations given in the guidelines, achieved by a dedicated test session inside the Municipal Theatre of Ferrara.

Energy efficient engine: Low-pressure turbine subsonic cascade component development and integration program

NASA Technical Reports Server (NTRS)

Sharma, O. P.; Kopper, F. C.; Knudsen, L. K.; Yustinich, J. B.

1982-01-01

A subsonic cascade test program was conducted to provide technical data for optimizing the blade and vane airfoil designs for the Energy Efficient Engine Low-Pressure Turbine component. The program consisted of three parts. The first involved an evaluation of the low-chamber inlet guide vane. The second, was an evaluation of two candidate aerodynamic loading philosophies for the fourth blade root section. The third part consisted of an evaluation of three candidate airfoil geometries for the fourth blade mean section. The performance of each candidate airfoil was evaluated in a linear cascade configuration. The overall results of this study indicate that the aft-loaded airfoil designs resulted in lower losses which substantiated Pratt & Whitney Aircraft's design philosophy for the Energy Efficient Engine low-pressure turbine component.

The Language of Man. Book 4.

ERIC Educational Resources Information Center

Littell, Joseph Fletcher, Ed.

Book 4 of "The Language of Man" series contains articles which deal with semantics, levels of language (including informal, formal and technical language, jargon, and gobbledygook), the hidden persuaders (advertising of merchandise and political candidates), and communications of the future (including the computer and other mass media now being…

ESGE-ESGENA technical specification for process validation and routine testing of endoscope reprocessing in washer-disinfectors according to EN ISO 15883, parts 1, 4, and ISO/TS 15883-5.

PubMed

Beilenhoff, Ulrike; Biering, Holger; Blum, Reinhard; Brljak, Jadranka; Cimbro, Monica; Dumonceau, Jean-Marc; Hassan, Cesare; Jung, Michael; Neumann, Christiane; Pietsch, Michael; Pineau, Lionel; Ponchon, Thierry; Rejchrt, Stanislav; Rey, Jean-François; Schmidt, Verona; Tillett, Jayne; van Hooft, Jeanin

2017-12-01

1 Prerequisites. The clinical service provider should obtain confirmation from the endoscope washer-disinfector (EWD) manufacturer that all endoscopes intended to be used can be reprocessed in the EWD. 2 Installation qualification. This can be performed by different parties but national guidelines should define who has the responsibilities, taking into account legal requirements. 3 Operational qualification. This should include parametric tests to verify that the EWD is working according to its specifications. 4 Performance qualification. Testing of cleaning performance, microbiological testing of routinely used endoscopes, and the quality of the final rinse water should be considered in all local guidelines. The extent of these tests depends on local requirements. According to the results of type testing performed during EWD development, other parameters can be tested if local regulatory authorities accept this. Chemical residues on endoscope surfaces should be searched for, if acceptable test methods are available. 5 Routine inspections. National guidelines should consider both technical and performance criteria. Individual risk analyses performed in the validation and requalification processes are helpful for defining appropriate test frequencies for routine inspections. © Georg Thieme Verlag KG Stuttgart · New York.

Understanding a technical language: A schema-based approach

NASA Technical Reports Server (NTRS)

Falzon, P.

1984-01-01

Workers in many job categories tend to develop technical languages, which are restricted subjects of natural language. A better knowledge of these retrictions provides guidelines for the design of the restricted languages of interactive systems. Accordingly, a technical language used by air-traffic controllers in their communications with pilots was studied. A method of analysis is presented that allows the schemata underlying each category of messages to be identified. This schematic knowledge was implemented in programs, which assume that the goal-oriented aspect of technical languages (and particularly the restricted domain of discourse) limits the processes and the data necessary in order to understand the messages (monosemy, limited vocabulary, evocation of the schemata by some command words, absence of syntax). The programs can interpret, and translate into sequences of action, the messages emitted by the controllers.

Implementation plans included in World Health Organisation guidelines.

PubMed

Wang, Zhicheng; Norris, Susan L; Bero, Lisa

2016-05-20

The implementation of high-quality guidelines is essential to improve clinical practice and public health. The World Health Organisation (WHO) develops evidence-based public health and other guidelines that are used or adapted by countries around the world. Detailed implementation plans are often necessary for local policymakers to properly use the guidelines developed by WHO. This paper describes the plans for guideline implementation reported in WHO guidelines and indicates which of these plans are evidence-based. We conducted a content analysis of the implementation sections of WHO guidelines approved by the WHO guideline review committee between December 2007 and May 2015. The implementation techniques reported in each guideline were coded according to the Cochrane Collaboration's Effective Practice and Organisation of Care (EPOC) taxonomy and classified as passive, active or policy strategies. The frequencies of implementation techniques are reported. The WHO guidelines (n = 123) analysed mentioned implementation techniques 800 times, although most mentioned implementation techniques very briefly, if at all. Passive strategies (21 %, 167/800) and general policy strategies (62 %, 496/800) occurred most often. Evidence-based active implementation methods were generally neglected with no guideline mentioning reminders (computerised or paper) and only one mentioning a multifaceted approach. Many guidelines contained implementation sections that were identical to those used in older guidelines produced by the same WHO technical unit. The prevalence of passive and policy-based implementation techniques as opposed to evidence-based active techniques suggests that WHO guidelines should contain stronger guidance for implementation. This could include structured and increased detail on implementation considerations, accompanying or linked documents that provide information on what is needed to contextualise or adapt a guideline and specific options from among evidence-based implementation strategies.

Enabling Curricula: The Development of a Teaching Observation Protocol to Address Students' Diverse Learning Needs

ERIC Educational Resources Information Center

Hayden, Sharon

2011-01-01

Diverse learning needs are students' learning needs in areas such as language, learning styles, background, disabilities, technology skills, motivation, engagement, and access. Teacher candidates must be aware of and plan to meet these needs. The Universal Design for Learning (UDL) provides guidelines that can increase the level of student…

Annual Research Review: Impact of Advances in Genetics in Understanding Developmental Psychopathology

ERIC Educational Resources Information Center

Addington, Anjene M.; Rapoport, Judith L.

2012-01-01

It was hoped that diagnostic guidelines for, and treatment of, child psychiatric disorders in DSM-5 would be informed by the wealth of clinical genetic research related to neurodevelopmental disorders. In spite of remarkable advances in genetic technology, this has not been the case. Candidate gene, genome-wide association, and rare copy number…

Report of the Peer Review Panel on the early site suitability evaluation of the Potential Repository Site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1992-01-01

The US Department of Energy (DOE) Yucca mountain Site Characterization Project Office (YMPO) assigned Science Applications International Corporation (SAIC), the Technical and Management Support Services (T&MSS) contractor to the YmPo, the task of conducting an Early Site Suitability Evaluation (ESSE) of the Yucca mountain site as a potential site for a high-level radioactive waste repository. First, the assignment called for the development of a method to evaluate a single site against the DOE General Guidelines for Recommendation of Sites for Nuclear Waste Repositories, 10 CFR Part 960. Then, using this method, an evaluation team, the ESSE Core Team, of seniormore » YMP scientists, engineers, and technical experts, evaluated new information obtained about the site since publication of the final Environmental Assessment (DOE, 1986) to determine if new suitability/unsuitability findings could be recommended. Finally, the Core Team identified further information and analyses needed to make final determinations for each of the guidelines. As part of the task, an independent peer review of the ESSE report has been conducted. Expertise was solicited that covered the entire spectrum of siting guidelines in 10 CFR Part 960 in order to provide a complete, in-depth critical review of the data evaluated and cited in the ESSE report, the methods used to evaluate the data, and the conclusions and recommendations offered by the report. Fourteen nationally recognized technical experts (Table 2) served on the Peer Review Panel. The comments from the Panel and the responses prepared by the ESSE Core Team, documented on formal Comment Response Forms, constitute the body of this document.« less

Space Environmental Effects Testing and Characterization of the Candidate Solar Sail Material Aluminized Mylar

NASA Technical Reports Server (NTRS)

Edwards, D. L.; Hubbs, W. S.; Wertz, G. E.; Alstatt, R.; Munafo, Paul (Technical Monitor)

2001-01-01

The usage of solar sails as a propellantless propulsion system has been proposed for many years. The technical challenges associated with solar sails are fabrication of ultralightweight films, deploying the sails and controlling the spacecraft. Integral to all these challenges is the mechanical property integrity of the sail while exposed to the harsh environment of space. This paper describes testing and characterization of a candidate solar sail material, Aluminized Mylar. This material was exposed to a simulated Geosynchronous Transfer Orbit (GTO) and evaluated by measuring thermooptical and mechanical property changes. Testing procedures and results are presented.

Estimating the size of key populations at higher risk of HIV infection: a summary of experiences and lessons presented during a technical meeting on size estimation among key populations in Asian countries

PubMed Central

Calleja, Jesus Maria Garcia; Zhao, Jinkou; Reddy, Amala; Seguy, Nicole

2014-01-01

Problem Size estimates of key populations at higher risk of HIV exposure are recognized as critical for understanding the trajectory of the HIV epidemic and planning and monitoring an effective response, especially for countries with concentrated and low epidemics such as those in Asia. Context To help countries estimate population sizes of key populations, global guidelines were updated in 2011 to reflect new technical developments and recent field experiences in applying these methods. Action In September 2013, a meeting of programme managers and experts experienced with population size estimates (PSE) for key populations was held for 13 Asian countries. This article summarizes the key results presented, shares practical lessons learnt and reviews the methodological approaches from implementing PSE in 13 countries. Lessons learnt It is important to build capacity to collect, analyse and use PSE data; establish a technical review group; and implement a transparent, well documented process. Countries should adapt global PSE guidelines and maintain operational definitions that are more relevant and useable for country programmes. Development of methods for non-venue-based key populations requires more investment and collaborative efforts between countries and among partners. PMID:25320676

10 CFR 300.9 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-01-01

... these guidelines, all reports must conform to the measurement methods established by the Technical... justification. (3) If a change in calculation methods (for inventories or reductions) is made for a particular year, the reporting entity must, if feasible, revise its base value to assure methodological...

10 CFR 300.9 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-01-01

... these guidelines, all reports must conform to the measurement methods established by the Technical... justification. (3) If a change in calculation methods (for inventories or reductions) is made for a particular year, the reporting entity must, if feasible, revise its base value to assure methodological...

10 CFR 300.9 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-01-01

... these guidelines, all reports must conform to the measurement methods established by the Technical... justification. (3) If a change in calculation methods (for inventories or reductions) is made for a particular year, the reporting entity must, if feasible, revise its base value to assure methodological...

10 CFR 300.9 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... these guidelines, all reports must conform to the measurement methods established by the Technical... justification. (3) If a change in calculation methods (for inventories or reductions) is made for a particular year, the reporting entity must, if feasible, revise its base value to assure methodological...

10 CFR 300.9 - Reporting and recordkeeping requirements.

Code of Federal Regulations, 2011 CFR

2011-01-01

... these guidelines, all reports must conform to the measurement methods established by the Technical... justification. (3) If a change in calculation methods (for inventories or reductions) is made for a particular year, the reporting entity must, if feasible, revise its base value to assure methodological...

Continuity diaphragm for skewed continuous span precast prestressed concrete girder bridges : technical summary report.

DOT National Transportation Integrated Search

2004-03-01

Most highway bridges are built as cast-in-place : reinforced concrete slabs and prestressed concrete : girders. The shear connectors on the top of the girders : assure composite action between the slabs and : girders. The design guidelines for bridge...

Development of guidelines for triple left and dual right-turn lanes : technical report.

DOT National Transportation Integrated Search

2011-07-01

Left- or right-turn lanes at intersections improve safety and operations by separating turning and through vehicles. At intersections : with heavy turning demand, it may be necessary to provide multiple turn lanes. Triple left-turn (TLT) and dual rig...

A Vocational Program Articulation Process.

ERIC Educational Resources Information Center

Hobert, Freemont; Smith, Art

This manual provides guidelines for implementing the articulation process for vocational/technical programs at California community colleges as set up by the 71 Regional Adult and Vocational Education Councils. An introductory section reviewing the adaptation of the process to local needs, selection of participants, staff and program, basic…

Full Text Journal Subscriptions: An Evolutionary Process.

ERIC Educational Resources Information Center

Luther, Judy

1997-01-01

Provides an overview of companies offering Web accessible subscriptions to full text electronic versions of scientific, technical, and medical journals (Academic Press, Blackwell, EBSCO, Elsevier, Highwire Press, Information Quest, Institute of Physics, Johns Hopkins University Press, OCLC, OVID, Springer, and SWETS). Also lists guidelines for…

Comprehensive Testing Guidelines to Increase Efficiency in INDOT Operations : [Technical Summary

DOT National Transportation Integrated Search

2012-01-01

When the Indiana Department of Transportation designs a pavement project, a decision for QC/QA (Quality Control/ Quality Assurance) or nonQC/QA is made solely based on the quantity of pavement materials to be used in the project. Once the pavement...

Comprehensive Testing Guidelines to Increase Efficiency in INDOT Operations : [Technical Summary

DOT National Transportation Integrated Search

2012-01-01

When the Indiana Department of Transportation designs : a pavement project, a decision for QC/QA (Quality Control/ : Quality Assurance) or nonQC/QA is made solely : based on the quantity of pavement materials to be used : in the project. Once the ...

77 FR 5155 - Interest Rate Risk Policy and Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

... directors and management; appropriate IRR measurement and monitoring systems; good internal controls; and informed decision-making based on IRR measurement system results. It also provides guidelines for... technical aspects of IRR measurement methods. Of these, some said Appendix B implied a preference for the...

Statements of work handbook. [technical writing for NASA programs

NASA Technical Reports Server (NTRS)

1975-01-01

Guidelines are presented for preparing statements of work (SOW) to assure a consistent approach throughout NASA. Statements of work for study and preliminary definition contracts, for definition and development of major systems, for support services, and for small research and development contracts are discussed.

45 CFR 1180.70 - Guidelines and standards for museum conservation projects.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) Technical examination of materials and surveys of environmental and collection conditions; (2) Provision... additions or accretions, and physical compensation for losses; species survival activities; and (4) Research..., including— (i) Projects involving surveys of conservation needs and (ii) Projects to establish or maintain...

45 CFR 1180.70 - Guidelines and standards for museum conservation projects.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) Technical examination of materials and surveys of environmental and collection conditions; (2) Provision... additions or accretions, and physical compensation for losses; species survival activities; and (4) Research..., including— (i) Projects involving surveys of conservation needs and (ii) Projects to establish or maintain...

45 CFR 1180.70 - Guidelines and standards for museum conservation projects.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Technical examination of materials and surveys of environmental and collection conditions; (2) Provision... additions or accretions, and physical compensation for losses; species survival activities; and (4) Research..., including— (i) Projects involving surveys of conservation needs and (ii) Projects to establish or maintain...

43 CFR 2.51 - Assuring integrity of records.

Code of Federal Regulations, 2011 CFR

2011-10-01

... on those recommended in the National Bureau of Standard's booklet “Computer Security Guidelines for..., technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or integrity which could result in...

43 CFR 2.51 - Assuring integrity of records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... on those recommended in the National Bureau of Standard's booklet “Computer Security Guidelines for..., technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or integrity which could result in...

43 CFR 2.51 - Assuring integrity of records.

Code of Federal Regulations, 2012 CFR

2012-10-01

... on those recommended in the National Bureau of Standard's booklet “Computer Security Guidelines for..., technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or integrity which could result in...

43 CFR 2.226 - Assuring integrity of records.

Code of Federal Regulations, 2014 CFR

2014-10-01

... on those recommended in the National Bureau of Standard's booklet “Computer Security Guidelines for..., technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or integrity which could result in...

43 CFR 2.226 - Assuring integrity of records.

Code of Federal Regulations, 2013 CFR

2013-10-01

... on those recommended in the National Bureau of Standard's booklet “Computer Security Guidelines for..., technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or integrity which could result in...

Practical application of AMLCDs for tactical fighter aircraft

NASA Astrophysics Data System (ADS)

McClaskey, Paul; Craddock, Roger

1995-06-01

Development and testing of an AMLCD-display to replace a dichroic display in a fighter aircraft environment has presented a unique set of technical challenges. This paper addresses design concepts used on the Engine Fuel Display and proposes design guidelines generally applicable for AMLCD projects.

PRODUCT LIFE-CYCLE ASSESSMENT: INVENTORY GUIDELINES AND PRINCIPLES

EPA Science Inventory

The Life Cycle Assessment (LCA) can be used as an objective technical tool to evaluate the environmental consequences of a product, process, or activity holistically, across its entire life cycle. omplete LCA can be viewed as consisting of three complementary components (1) the i...

7 CFR 3203.9 - Accountability and recordkeeping.

Code of Federal Regulations, 2014 CFR

2014-01-01

... recordkeeping. (a) USDA requires all excess computers or other technical equipment received by an eligible... review the reports for accuracy, as well as fair and equitable distribution of the excess computers or... PROPERTY MANAGEMENT, DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE TRANSFER OF EXCESS COMPUTERS OR OTHER...

7 CFR 3203.9 - Accountability and recordkeeping.

Code of Federal Regulations, 2013 CFR

2013-01-01

... recordkeeping. (a) USDA requires all excess computers or other technical equipment received by an eligible... review the reports for accuracy, as well as fair and equitable distribution of the excess computers or... PROPERTY MANAGEMENT, DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE TRANSFER OF EXCESS COMPUTERS OR OTHER...

Guideline group composition and group processes: article 3 in Integrating and coordinating efforts in COPD guideline development. An official ATS/ERS workshop report.

PubMed

Kunz, Regina; Fretheim, Atle; Cluzeau, Françoise; Wilt, Timothy J; Qaseem, Amir; Lelgemann, Monika; Kelson, Marcia; Guyatt, Gordon; Schünemann, Holger J

2012-12-01

Professional societies, like many other organizations around the world, have recognized the need to use more rigorous processes to ensure that health care recommendations are informed by the best available research evidence. This is the third of a series of 14 articles that were prepared to advise guideline developers in respiratory and other diseases on considerations for group compositions and group processes in guideline development, and how this can be effectively integrated in the context of respiratory disease guidelines on a national and international level. We updated a review of the literature addressing group composition and group process, focusing on the following questions: 1. How to compose a functioning and representative guideline group; Who should be included in a guideline panel?; How to select organizations, groups, and individuals; What expertise is needed?; Consultation with non-included groups. 2. How to assure a functioning group process; How to make the process constructive; Balancing participation and finding agreement; Administrative support; What constitutes sufficient resources? Our conclusions are based on available evidence from published literature, experience from guideline developers, and workshop discussions. Formal studies addressing optimal processes in developing guidelines are limited, and experience from guideline organizations supplement the formal studies. When resources are available, guideline development groups should aim for multidisciplinary groups, including patients. Prerequisites for a multidisciplinary group include: a strong chair experienced in group facilitation with broad acceptance in the group, training the group in guideline methodology, and professional technical support. Formal consensus developing methods have proved effective in reaching agreement on the final recommendations.

Can-Do-Hub: The GitHub of Competencies

ERIC Educational Resources Information Center

Weise, Michelle R.

2016-01-01

The debates between vocational/technical training and education are getting old. On one side, we have academics arguing for the timelessness of an education--learning that is not specifically tailored toward work or "the what." On the other side, there are employers retreating more and more from training candidates--and blaming…

77 FR 27869 - Medicare Program; Hospital Inpatient Prospective Payment Systems for Acute Care Hospitals and the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... Considered HAC Candidate: Iatrogenic Pneumothorax With Venous Catheterization 3. Present on Admission (POA.... History of Measures Adopted for the Hospital IQR Program b. Maintenance of Technical Specifications for...-Associated Infection (HAI) Measures (A) Proposed Central Line Associated Blood Stream Infections ((CLABSI...

Commercial Vehicle Fleet Management And Information Systems, Technical Memorandum 1, Classification Of Fleet Operations, And Selection Of Candidate Case-Study Fleets

DOT National Transportation Integrated Search

1994-11-04

THE ECONOMIC WELL-BEING AND COMPETITIVENESS OF THE U.S. ECONOMY DEPEND HEAVILY ON RELIABLE AND EFFICIENT FREIGHT MOVEMENTS. TRUCKING ACCOUNTS FOR ABOUT 75 PERCENT ($270 BILLION) OF THE $350 BILLION SPENT ANNUALLY ON FREIGHT TRANSPORTATION. THE APPLIC...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bailey, David H.

In a previous humorous note entitled 'Twelve Ways to Fool the Masses,' I outlined twelve common ways in which performance figures for technical computer systems can be distorted. In this paper and accompanying conference talk, I give a reprise of these twelve 'methods' and give some actual examples that have appeared in peer-reviewed literature in years past. I then propose guidelines for reporting performance, the adoption of which would raise the level of professionalism and reduce the level of confusion, not only in the world of device simulation but also in the larger arena of technical computing.

Maritime patrol aircraft engine study, General Electric Derivative Engines. Volume II. Appendix A: performance data, Ge27/T3 study A1 turboprop. Final report, October 1978-April 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hirschkron, R.; Davis, R.H.; Warren, R.E.

1979-04-30

This study developed data on General Electric common core derivative engines for use in Maritime Patrol Aircraft (MPA) concept formulation studies. The study included the screening of potential General Electric turbofan and turboprop/turboshaft engines and the preparation of technical and planning information on three of the most promising engine candidates. Screening of General Electric derivative candidates was performed utilizing an analytical MPA model using synthesized mission profiles to rank the candidates in terms of fuel consumption, weight, cost and complexity. The three turboprop engines selected for further study were as follows: TF34 growth derivative version with boost and new LPTmore » (TF34/T7 Study A1), F404 derivative with booster stages and new LPT (F404/T1 Study A1), and GE27 scaled and boosted study engine (GE27/T3 Study A1). Volume I summarizes the screening analysis and contains technical, planning, installation, cost and development data for the three selected turboprop engines. Volumes II, III and IV of this report contain the detailed performance data estimates for the GE27/T3 Study A1, TF34/T7 Study A1 and F404/T1 Study A1 turboprop engines, respectively.« less

Maritime patrol aircraft engine study, General Electric Derivative Engines. Volume IV. Apendix C: performance data, F404/T1 study A1 turboprop. Final report, October 1978-April 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hirschkron, R.; Davis, R.H.; Warren, R.E.

1979-04-30

This study developed data on General Electric common core derivative engines for use in Maritime Patrol Aircraft (MPA) concept formulation studies. The study included the screening of potential General Electric turbofan and turboprop/turboshaft engines and the preparation of technical and planning information on three of the most promising engine candidates. Screening of General Electric derivative candidates was performed utilizing an analytical MPA model using synthesized mission profiles to rank the candidates in terms of fuel consumption, weight, cost and complexity. The three turboprop engines selected for further study were as follows: TF34 growth derivative version with boost and new LPTmore » (TF34/T7 Study A1), F404 derivative with booster stages and new LPT (F404/T1 Study A1), and GE27 scaled and boosted study engine (GE27/T3 Study A1). Volume I summarizes the screening analysis and contains technical, planning, installation, cost and development data for the three selected turboprop engines. Volumes II, III and IV of this report contain the detailed performance data estimates for the GE27/T3 Study A1, TF34/T7 Study A1 and F404/T1 Study A1 turboprop engines, respectively.« less

Maritime patrol aircraft engine study, General Electric Derivative Engines. Volume III. Appendix B: performance data, TF 34/T7 study AL turboprop. Final report October 1978-April 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hirschkron, R.; Davis, R.H.; Warren, R.E.

1979-04-30

This study developed data on General Electric common core derivative engines for use in Maritime Patrol Aircraft (MPA) concept formulation studies. The study included the screening of potential General Electric turbofan and turboprop/turboshaft engines and the preparation of technical and planning information on three of the most promising engine candidates. Screening of General Electric derivative candidates was performed utilizing an analytical MPA model using synthesized mission profiles to rank the candidates in terms of fuel consumption, weight, cost and complexity. The three turboprop engines selected for further study were as follows: TF34 growth derivative version with boost and new LPTmore » (TF34/T7 Study A1), F404 derivative with booster stages and new LPT (F404/T1 Study A1), and GE27 scaled and boosted study engine (GE27/T3 Study A1). Volume I summarizes the screening analysis and contains technical, planning, installation, cost and development data for the three selected turboprop engines. Volumes II, III and IV of this report contain the detailed performance data estimates for the GE27/T3 Study A1, TF34/T7 Study A1 and F404/T1 Study A1 turboprop engines, respectively.« less

Knowledge Discovery in Biological Databases for Revealing Candidate Genes Linked to Complex Phenotypes.

PubMed

Hassani-Pak, Keywan; Rawlings, Christopher

2017-06-13

Genetics and "omics" studies designed to uncover genotype to phenotype relationships often identify large numbers of potential candidate genes, among which the causal genes are hidden. Scientists generally lack the time and technical expertise to review all relevant information available from the literature, from key model species and from a potentially wide range of related biological databases in a variety of data formats with variable quality and coverage. Computational tools are needed for the integration and evaluation of heterogeneous information in order to prioritise candidate genes and components of interaction networks that, if perturbed through potential interventions, have a positive impact on the biological outcome in the whole organism without producing negative side effects. Here we review several bioinformatics tools and databases that play an important role in biological knowledge discovery and candidate gene prioritization. We conclude with several key challenges that need to be addressed in order to facilitate biological knowledge discovery in the future.

Amelioration and retrofitting of educational buildings

NASA Astrophysics Data System (ADS)

Casciati, Fabio; Casciati, Sara

2018-01-01

Following a seismic event that occurred years ago in Central Italy, the public opinion was growing and growing a concern on the adequacy of educational buildings all across Italy. This activated several political decisions and a consequent technical effort is in progress. Technically speaking one has to manage the classical problem of retrofitting existing buildings. However, the legal environment goes across national codes, targeted guidelines and the professional need of achieving pragmatic solutions based on ethical and social acceptation schemes.This paper introduces the topic in its worldwide exception and focuses then on some operative aspects in the Italian situation. It outlines the consolidated steps along this technical process and emphasizes the weak aspects one meets when going across the designers' reports.

Lunar mission safety and rescue: Technical summary

NASA Technical Reports Server (NTRS)

1971-01-01

A technical summary is presented of the escape/rescue and the hazards analyses for manned missions and operations in the 1980 time frame. Hazards are interpreted as hazards to man, not to equipment, program schedule, or program objectives. Hazards in 39 individual areas are analyzed, and corrective measures are recommended. Over 200 safety guidelines are proposed, based on significant hazards. Escape and rescue situtations and requirements are identified and analyzed, and escape/survival/rescue concepts are defined to cope with each escape/rescue situation. Areas in which research or technical development efforts could improve mission safety are identified. It is concluded that the primary emphasis should be on survival and escape provisions, with rescue required only where self-help cannot bring the endangered crewmen to a safe haven.

A multinational report of technical factors on stereotactic body radiotherapy for oligometastases.

PubMed

Redmond, Kristin J; Lo, Simon S; Dagan, Roi; Poon, Ian; Foote, Matthew C; Erler, Darby; Lee, Young; Lohr, Frank; Biswas, Tithi; Ricardi, Umberto; Sahgal, Arjun

2017-05-01

Oligometastatic cancer is being increasingly managed with aggressive local therapy using stereotactic body radiation therapy (SBRT). However, few guidelines exist. We summarize the results of an international survey reviewing technical factors for extracranial SBRT for oligometastatic disease to guide safe management. Seven high-volume centers contributed. Levels of agreement were categorized as strong (6-7 common responses), moderate (4-5), low (2-3) or no agreement. We present the results of a multi-national and multi-institutional survey of technical factors of SBRT for extracranial oligometastases. Key methods including target delineation, prescription doses, normal tissue constraints, imaging and set-up for safe implementation and practice of SBRT for oligometastasis have been identified. This manuscript will serve as a foundation for future clinical evaluations.

7 CFR 2812.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the donation of excess research equipment to educational institutions and non-profit organizations for the conduct of technical and scientific education and research activities as authorized by 15 U.S.C... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

7 CFR 2812.1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the donation of excess research equipment to educational institutions and non-profit organizations for the conduct of technical and scientific education and research activities as authorized by 15 U.S.C... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

7 CFR 2812.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the donation of excess research equipment to educational institutions and non-profit organizations for the conduct of technical and scientific education and research activities as authorized by 15 U.S.C... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

7 CFR 2812.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the donation of excess research equipment to educational institutions and non-profit organizations for the conduct of technical and scientific education and research activities as authorized by 15 U.S.C... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

Creep behavior of soil nail walls in high plasticity index (PI) soils : technical report.

DOT National Transportation Integrated Search

2017-04-01

An aspect of particular concern in the Geotechnical Engineering Circular No. 7: Soil Nail Walls (i.e., the soil : nail wall manual and construction guidelines) is the creep behavior of soil nail systems in high-plasticity : clays. This research proje...

Development of performance-based guidelines for selection of bituminous-based hot-poured pavement crack sealant : an executive summary report.

DOT National Transportation Integrated Search

2009-01-01

This report summarizes research presented in separate technical reports, papers, and journal articles that collectively document the development of a systematic process to aid in the selection of appropriate bituminous hot-poured sealants for pavemen...

POLICIES AND GUIDELINES FOR THE TRAINING OF DENTAL AUXILIARIES.

ERIC Educational Resources Information Center

American Dental Association, Chicago, IL. Council on Dental Education.

ALTHOUGH THE DENTAL PROFESSION NOW SEEKS SUPPORT FOR AUXILIARY TRAINING PROGRAMS FROM EDUCATIONAL INSTITUTES OTHER THAN DENTAL SCHOOLS, IT IS CONCERNED THAT TRAINING IN NONDENTAL SCHOOL SETTINGS SUCH AS JUNIOR COLLEGES, TECHNICAL INSTITUTES, UNIVERSITY EXTENSION PROGRAMS, AND POST-HIGH SCHOOL VOCATIONAL PROGRAMS PREVENTS TRAINEE EXPOSURE TO…

Systematic Treatment Selection (STS): A Review and Future Directions

ERIC Educational Resources Information Center

Nguyen, Tam T.; Bertoni, Matteo; Charvat, Mylea; Gheytanchi, Anahita; Beutler, Larry E.

2007-01-01

Systematic Treatment Selection (STS) is a form of technical eclectism that develops and plans treatments using empirically founded principles of psychotherapy. It is a model that provides systematic guidelines for the utilization of different psychotherapeutic strategies based on patient qualities and problem characteristics. Historically, it…

Guidelines for Local Governments on Solid Waste Management.

ERIC Educational Resources Information Center

National Association of Counties, Washington, DC. Research Foundation.

This document consists of ten guides on Solid Waste Management to assist local elected and appointed policy-making officials. They are entitled: Areawide Approaches; Legal Authority, Planning, Organization Design and Operation, Financing, Technical and Financial Assistance, Citizen Support, Personnel, and Action Plan and Bibliography. The guides…

Integrating Science and Technology into a Policy of Lifelong Education in Nigeria.

ERIC Educational Resources Information Center

Urevbu, Andrew O.

1985-01-01

Examines Nigeria's National Policy on Education guidelines, specifically focusing on science and technological education. Discusses the development of vocational and technical schools, transfer of technology, and the role of research institutes. Recommendations are made concerning academic survival skills, respect for manual skills, improved…

7 CFR 2812.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the donation of excess research equipment to educational institutions and non-profit organizations for the conduct of technical and scientific education and research activities as authorized by 15 U.S.C... DEPARTMENT OF AGRICULTURE GUIDELINES FOR THE DONATION OF EXCESS RESEARCH EQUIPMENT UNDER 15 U.S.C. 3710(i...

Improving Vocational Curriculum.

ERIC Educational Resources Information Center

Duenk, Lester G., Ed.

This book provides guidelines for those responsible for the development of contemporary curriculum for instruction in vocational-technical fields. It is a compendium of the various systems of teaching and testing for students training for a variety of occupations requiring specialized knowledge and skill development. The guide consists of 12…

The Learning Environment.

ERIC Educational Resources Information Center

American Electric Power System, New York, NY.

The basic factors in personal comfort, the nature of the processes of teaching and learning, and the effects of environment on these functions are discussed. The role of climate conditioning and space conditioning as interpreted by sensory factors during the learning process gives guidelines for design solutions. Technical supplements on climate…

36 CFR Exhibit A to Part 906 - Suggested Minimum Guidelines and Goals

Code of Federal Regulations, 2010 CFR

2010-07-01

... of materials and supplies to minority owned businesses. (g) Hotel employment—20 percent of all hotel... of trainees for hotel positions should be minority group members, women, handicapped persons, or... enterprises. (i) Committed opportunities—should be created for professional, technical, construction, hotel...

Evaluation of Texas native grasses for TxDOT right of ways : technical report.

DOT National Transportation Integrated Search

2009-05-01

The Texas Department of Transportation (TxDOT) has one of the largest right-of-way areas in the : United States with over 127,138 km of state maintained highway. In 2003, the new guidelines for Texas : Pollution Discharge Elimination System went into...

25 CFR 43.22 - Assuring integrity of records.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., “Computer Security Guidelines for Implementing the Privacy Act of 1974” (May 30, 1975), and any supplements... with appropriate administrative, technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or...

25 CFR 43.22 - Assuring integrity of records.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., “Computer Security Guidelines for Implementing the Privacy Act of 1974” (May 30, 1975), and any supplements... with appropriate administrative, technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or...

25 CFR 43.22 - Assuring integrity of records.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., “Computer Security Guidelines for Implementing the Privacy Act of 1974” (May 30, 1975), and any supplements... with appropriate administrative, technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or...

25 CFR 43.22 - Assuring integrity of records.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., “Computer Security Guidelines for Implementing the Privacy Act of 1974” (May 30, 1975), and any supplements... appropriate administrative, technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or integrity which...

25 CFR 43.22 - Assuring integrity of records.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., “Computer Security Guidelines for Implementing the Privacy Act of 1974” (May 30, 1975), and any supplements... with appropriate administrative, technical and physical safeguards to insure the security and confidentiality of records and to protect against any anticipated threats or hazards to their security or...

Care and Handling of Computer Magnetic Storage Media.

ERIC Educational Resources Information Center

Geller, Sidney B.

Intended for use by data processing installation managers, operating personnel, and technical staff, this publication provides a comprehensive set of care and handling guidelines for the physical/chemical preservation of computer magnetic storage media--principally computer magnetic tapes--and their stored data. Emphasis is placed on media…

Avoiding Twisted Pixels: Ethical Guidelines for the Appropriate Use and Manipulation of Scientific Digital Images

PubMed Central

2014-01-01

Digital imaging has provided scientists with new opportunities to acquire and manipulate data using techniques that were difficult or impossible to employ in the past. Because digital images are easier to manipulate than film images, new problems have emerged. One growing concern in the scientific community is that digital images are not being handled with sufficient care. The problem is twofold: (1) the very small, yet troubling, number of intentional falsifications that have been identified, and (2) the more common unintentional, inappropriate manipulation of images for publication. Journals and professional societies have begun to address the issue with specific digital imaging guidelines. Unfortunately, the guidelines provided often do not come with instructions to explain their importance. Thus they deal with what should or should not be done, but not the associated ‘why’ that is required for understanding the rules. This article proposes 12 guidelines for scientific digital image manipulation and discusses the technical reasons behind these guidelines. These guidelines can be incorporated into lab meetings and graduate student training in order to provoke discussion and begin to bring an end to the culture of “data beautification”. PMID:20567932

Avoiding twisted pixels: ethical guidelines for the appropriate use and manipulation of scientific digital images.

PubMed

Cromey, Douglas W

2010-12-01

Digital imaging has provided scientists with new opportunities to acquire and manipulate data using techniques that were difficult or impossible to employ in the past. Because digital images are easier to manipulate than film images, new problems have emerged. One growing concern in the scientific community is that digital images are not being handled with sufficient care. The problem is twofold: (1) the very small, yet troubling, number of intentional falsifications that have been identified, and (2) the more common unintentional, inappropriate manipulation of images for publication. Journals and professional societies have begun to address the issue with specific digital imaging guidelines. Unfortunately, the guidelines provided often do not come with instructions to explain their importance. Thus they deal with what should or should not be done, but not the associated 'why' that is required for understanding the rules. This article proposes 12 guidelines for scientific digital image manipulation and discusses the technical reasons behind these guidelines. These guidelines can be incorporated into lab meetings and graduate student training in order to provoke discussion and begin to bring an end to the culture of "data beautification".

To Post, or Not to Post, That Is the Question: Teachers Candidates' Social Networking Decisions and Professional Development Needs

ERIC Educational Resources Information Center

Crompton, Helen; Rippard, Kelly; Sommerfeldt, Jody

2016-01-01

This rise in the use of social networks presents new ethical, legal, and professional challenges for educators. Pre-service teachers need professional development to be cognizant of the content they are posting to personal social networks. The purpose of this mixed-methods study was to develop professional development guidelines to help…

Evidence-based guidelines for recommending cochlear implantation for postlingually deafened adults.

PubMed

Leigh, Jaime R; Moran, Michelle; Hollow, Rodney; Dowell, Richard C

2016-01-01

Adult selection criteria for cochlear implantation have been developed based on analysis of the post-operative performance of a large group of postlingually deafened adults. Original criteria published in 2004 were reviewed and amended to reflect outcomes currently being achieved by implant recipients. Retrospective review of 12-month post-operative speech perception performance of adults implanted at the Eye and Ear Hospital, Melbourne, Australia. A total of 382 postlingually deafened adults, using a Freedom, Nucleus 5, or CI422 Slim Straight cochlear implant were used to create a comparative set of data. Revised guidelines suggest that adults with postlingual hearing loss can now be considered cochlear implant candidates if they obtain scores of up to 55% for open-set phonemes in quiet in the ear to be implanted. Functional benefit may vary depending on the recipients' contralateral hearing. This study supports the provision of cochlear implants to candidates with significant residual hearing when at least one ear meets the criterion outlined above. Patient-specific counseling is required to ensure the potential to benefit predicted by the current model is acceptable to the individual patient and their family. Counseling regarding functional benefit must take into consideration hearing in the contralateral ear.

Measure Guideline: Buried and/or Encapsulated Ducts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shapiro, C.; Zoeller, W.; Mantha, P.

2013-08-01

Buried and/or encapsulated ducts (BEDs) are a class of advanced, energy-efficiency strategies intended to address the significant ductwork thermal losses associated with ducts installed in unconditioned attics. BEDs are ducts installed in unconditioned attics that are covered in loose-fill insulation and/or encapsulated in closed cell polyurethane spray foam insulation. This Measure Guideline covers the technical aspects of BEDs as well as the advantages, disadvantages, and risks of BEDs compared to other alternative strategies. This guideline also provides detailed guidance on installation of BEDs strategies in new and existing homes through step-by-step installation procedures. Some of the procedures presented here, however,more » require specialized equipment or expertise. In addition, some alterations to duct systems may require a specialized license.« less

Transition management - An analysis of strategic considerations for effective implementation

NASA Technical Reports Server (NTRS)

Hunsucker, John L.; Loos, David

1989-01-01

Six managerial guidelines are identified for facilitating successful change in an organization. They are: (1) the need for a catalyst to initiate change; (2) the setting of organizational goals which take into account the impact of technical, political, and cultural factors; (3) requiring a transition team to guide the change; (4) a demonstration by top management of a commitment to the change as well as their acting as change agents; (5) the utilization of employee participation and good communication to help overcome employee resistance; and (6) the evaluation of the change program as important to the success of present and future change programs. A description of each guideline is presented, and its importance is examined. Available options are also presented for management to deal with each of the guidelines.

WHO Expert Committee on Specifications for Pharmaceutical Preparations. Forty-ninth report.

PubMed

2015-01-01

The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensus-building process. The following new guidelines were adopted and recommended for use. Revised procedure for the development of monographs and other texts for The International Pharmacopoeia; Revised updating mechanism for the section on radiopharmaceuticals in The International Pharmacopoeia; Revision of the supplementary guidelines on good manufacturing practices: validation, Appendix 7: non-sterile process validation; General guidance for inspectors on hold-time studies; 16 technical supplements to Model guidance for the storage and transport of time- and temperature-sensitive pharmaceutical products; Recommendations for quality requirements when plant-derived artemisinin is used as a starting material in the production of antimalarial active pharmaceutical ingredients; Multisource (generic) pharmaceutical products: guidelines on registration requirements to establish interchangeability: revision; Guidance on the selection of comparator pharmaceutical products for equivalence assessment of interchangeable multisource (generic) products: revision; and Good review practices: guidelines for national and regional regulatory authorities.

Human milk banking guidelines.

PubMed

Bharadva, Ketan; Tiwari, Satish; Mishra, Sudhir; Mukhopadhyay, Kanya; Yadav, Balraj; Agarwal, R K; Kumar, Vishesh

2014-06-01

WHO and UNICEF state that the use of human milk from other sources should be the first alternative when it is not possible for the mother to breastfeed. Human milk banks should be made available in appropriate situations. The IYCF Chapter is actively concerned about the compelling use of formula feeds in the infants because of the non availability of human breast milk banks. A National Consultative Meet for framing guidelines was summoned by the IYCF Chapter and the Ministry of Health and Family Welfare, Government of India on 30th June, 2013, with representations from various stakeholders. The guidelines were drafted after an extensive literature review and discussions. Though these guidelines are based on the experiences and guidelines from other countries, changes have been made to suit the Indian setup, culture and needs, without compromising scientific evidence. To ensure quality of donated breast milk as a safe end product. Human Milk Banking Association should be constituted, and human milk banks should be established across the country. National coordination mechanism should be developed with a secretariat and technical support to follow-up on action in States. Budgetary provisions should be made available for the activities.

Beyond good intentions: lessons on equipment donation from an African hospital.

PubMed

Howie, Stephen R C; Hill, Sarah E; Peel, David; Sanneh, Momodou; Njie, Malick; Hill, Philip C; Mulholland, Kim; Adegbola, Richard A

2008-01-01

In 2000, a referral hospital in the Gambia accepted a donation of oxygen concentrators to help maintain oxygen supplies. The concentrators broke down and were put into storage. A case study was done to find the reasons for the problem and to draw lessons to help improve both oxygen supplies and the success of future equipment donations. A technical assessment of the concentrators was carried out by a biomedical engineer with relevant expertise. Semi-structured interviews were undertaken with key informants, and content analysis and inductive approaches were applied to construct the history of the episode and the reasons for the failure. Interviews confirmed the importance of technical problems with the equipment. They also revealed that the donation process was flawed, and that the hospital did not have the expertise to assess or maintain the equipment. Technical assessment showed that all units had the wrong voltage and frequency, leading to overheating and breakdown. Subsequently a hospital donations committee was established to oversee the donations process. On-site biomedical engineering expertise was arranged with a nongovernmental organization (NGO) partner. Appropriate donations of medical equipment, including oxygen concentrators, can be of benefit to hospitals in resource-poor settings, but recipients and donors need to actively manage donations to ensure that the donations are beneficial. Success requires planning, technical expertise and local participation. Partners with relevant skills and resources may also be needed. In 2002, WHO produced guidelines for medical equipment donations, which address problems that might be encountered. These guidelines should be publicized and used.

Beyond good intentions: lessons on equipment donation from an African hospital

PubMed Central

Hill, Sarah E; Peel, David; Sanneh, Momodou; Njie, Malick; Hill, Philip C; Mulholland, Kim; Adegbola, Richard A

2008-01-01

Abstract Objective In 2000, a referral hospital in the Gambia accepted a donation of oxygen concentrators to help maintain oxygen supplies. The concentrators broke down and were put into storage. A case study was done to find the reasons for the problem and to draw lessons to help improve both oxygen supplies and the success of future equipment donations. Methods A technical assessment of the concentrators was carried out by a biomedical engineer with relevant expertise. Semi-structured interviews were undertaken with key informants, and content analysis and inductive approaches were applied to construct the history of the episode and the reasons for the failure. Findings Interviews confirmed the importance of technical problems with the equipment. They also revealed that the donation process was flawed, and that the hospital did not have the expertise to assess or maintain the equipment. Technical assessment showed that all units had the wrong voltage and frequency, leading to overheating and breakdown. Subsequently a hospital donations committee was established to oversee the donations process. On-site biomedical engineering expertise was arranged with a nongovernmental organization (NGO) partner. Conclusion Appropriate donations of medical equipment, including oxygen concentrators, can be of benefit to hospitals in resource-poor settings, but recipients and donors need to actively manage donations to ensure that the donations are beneficial. Success requires planning, technical expertise and local participation. Partners with relevant skills and resources may also be needed. In 2002, WHO produced guidelines for medical equipment donations, which address problems that might be encountered. These guidelines should be publicized and used. PMID:18235890

Satellite power system concept development and evaluation program. Volume 1: Technical assessment summary report

NASA Technical Reports Server (NTRS)

1980-01-01

Candidate satellite power system (SPS) concepts were identified and evaluated in terms of technical and cost factors. A number of alternative technically feasible approaches and system concepts were investigated. A reference system was defined to facilitate economic, environmental, and societal assessments by the Department of Energy. All elements of the reference system were defined including the satellite and all its subsystems, the orbital construction and maintenance bases, all elements of the space transportation system, the ground receiving station, and the associated industrial facilities for manufacturing the required hardware. The reference conclusions and remaining issues are stated for the following topical areas: system definition; energy conversion and power management; power transmission and reception; structures, controls, and materials; construction and operations; and space transportation.

ATF Neutron Irradiation Program Technical Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geringer, J. W.; Katoh, Yutai

The Japan Atomic Energy Agency (JAEA) under the Civil Nuclear Energy Working Group (CNWG) is engaged in a cooperative research effort with the U.S. Department of Energy (DOE) to explore issues related to nuclear energy, including research on accident-tolerant fuels and materials for use in light water reactors. This work develops a draft technical plan for a neutron irradiation program on the candidate accident-tolerant fuel cladding materials and elements using the High Flux Isotope Reactor (HFIR). The research program requires the design of a detailed experiment, development of test vehicles, irradiation of test specimens, possible post-irradiation examination and characterization ofmore » irradiated materials and the shipment of irradiated materials to JAEA in Japan. This report discusses the technical plan of the experimental study.« less

Design considerations for community mental health management information systems.

PubMed

Lowe, B H; Sugarman, B

1978-01-01

Many community mental health centers are presently faced with the necessity of implementing a management information system. This article offers guidelines for centers dealing with this situation. Whether a center chooses to adapt an existing system or develop one of its own, careful planning prior to the implementation of the system can help ensure that it will meet the needs of the center and operate successfully. The guidelines are organized into the categories of data considerations, people considerations, and system considerations. The first two categories are of general interest, whereas the last category is more technical in nature.

Improving the adaptability of WHO evidence-informed guidelines for nutrition actions: results of a mixed methods evaluation.

PubMed

Dedios, Maria Cecilia; Esperato, Alexo; De-Regil, Luz Maria; Peña-Rosas, Juan Pablo; Norris, Susan L

2017-03-21

Over the past decade, the World Health Organization (WHO) has implemented a standardized, evidence-informed guideline development process to assure technically sound and policy-relevant guidelines. This study is an independent evaluation of the adaptability of the guidelines produced by the Evidence and Programme Guidance unit, at the Department of Nutrition for Health and Development (NHD). The study systematizes the lessons learned by the NHD group at WHO. We used a mixed methods approach to determine the adaptability of the nutrition guidelines. Adaptability was defined as having two components; methodological quality and implementability of guidelines. Additionally, we gathered recommendations to improve future guideline development in nutrition actions for health and development. Data sources for this evaluation were official documentation and feedback (both qualitative and quantitative) from key stakeholders involved in the development of nutrition guidelines. The qualitative data was collected through a desk review and two waves of semi-structured interviews (n = 12) and was analyzed through axial coding. Guideline adaptability was assessed quantitatively using two standardized instruments completed by key stakeholders. The Appraisal Guideline for Research and Evaluation questionnaire, version II was used to assess guideline quality (n = 6), while implementability was assessed with the electronic version of the GuideLine Implementability Appraisal (n = 7). The nutrition evidence-informed guideline development process has several strengths, among them are the appropriate management of conflicts of interest of guideline developers and the systematic use of high-quality evidence to inform the recommendations. These features contribute to increase the methodological quality of the guidelines. The key areas for improvement are the limited implementability of the recommendations, the lack of explicit and precise implementation advice in the guidelines and challenges related to collaborative work within interdisciplinary groups. Overall, our study found that the nutrition evidence-informed guidelines are of good methodological quality but that the implementability requires improvement. The recommendations to improve guideline adaptability address the guideline content, the dynamics shaping interdisciplinary work, and actions for implementation feasibility. As WHO relies heavily on a standardized procedure to develop guidelines, the lessons learned may be applicable to guideline development across the organization and to other groups developing guidelines.

75 FR 15597 - Ensuring Enforcement and Implementation of Abortion Restrictions in the Patient Protection and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

... generally accepted accounting principles, OMB funds management circulars, and accounting guidance provided... exchanges that will be operational in 2014. The Act also imposes strict payment and accounting requirements... Federal financial assistance. The guidelines shall also offer technical information that States should...

Guidelines for replacement of deficient bridges with low-water stream crossings in the rural Midwest : technical summary.

DOT National Transportation Integrated Search

2017-02-01

This report provides guidance to public officials and engineers considering the replacement of a deficient or obsolete bridge with a low-water stream crossing (LWSC). An LWSC is a structure that is occasionally overtopped by floodwaters and is likely...

Diesel Mechanics: Meeting Tomorrow's Training Needs.

ERIC Educational Resources Information Center

Schulz, Erich J.

1978-01-01

As the use of diesel engines in motor vehicles and heavy equipment increases, the need for skilled diesel mechanics will increase. The author describes education and training needs in schools and industry, gives guidelines for trade and technical curricula, and outlines the kinds of training materials to be developed. (MF)

Interoperability Is the Foundation for Successful Internet Telephony.

ERIC Educational Resources Information Center

Fromm, Larry

1997-01-01

More than 40 leading computer and telephony companies have united to lead the charge toward open standards and universal interoperability for Internet telephony products. The voice of IP Forum (VoIP) is working to define technical guidelines for two-party, real-time communications over IP networks, including provisions for compatibility with…

Technology Transfer and Risk Management.

ERIC Educational Resources Information Center

Goldstein, Michael B.

This pamphlet offers a series of self-assessment guidelines and questions which college and university officials can use to help determine the extent to which they are taking the appropriate measures to reasonably protect the institution's interests, maximize the economic value of technical discoveries made by faculty, and still maintain an…

Integrating the Science of Team Training: Guidelines for Continuing Education

ERIC Educational Resources Information Center

Weaver, Sallie J.; Rosen, Michael A.; Salas, Eduardo; Baum, Karyn D.; King, Heidi B.

2010-01-01

The provision of high-quality, efficient care results from the coordinated, cooperative efforts of multiple technically competent health care providers working in concert over time, spanning disciplinary and professional boundaries. Accordingly, the role of medical education must include the development of providers who are both expert clinicians…

7 CFR 12.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... conservation technology, and the standards and guidelines contained in the NRCS field office technical guides... field if farming practices make it probable that the croplines are not subject to change. Any highly... farming operations on the farm during the crop year. Owner means a person who is determined to have legal...

7 CFR 12.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... conservation technology, and the standards and guidelines contained in the NRCS field office technical guides... field if farming practices make it probable that the croplines are not subject to change. Any highly... farming operations on the farm during the crop year. Owner means a person who is determined to have legal...

7 CFR 12.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... conservation technology, and the standards and guidelines contained in the NRCS field office technical guides... field if farming practices make it probable that the croplines are not subject to change. Any highly... farming operations on the farm during the crop year. Owner means a person who is determined to have legal...

Postsecondary Vocational Programs vs. Apprenticeships in American Culinary Arts.

ERIC Educational Resources Information Center

VanLandingham, Paul G.

The apprenticeship system in the United States is primarily a private institution, separate from vocational-technical schools. Apprenticeships establish their own guidelines as to the required course of study. Apprentices do not get licensed unless they successfully complete a written and practical exam. Culinary apprenticeships vary. Many large…

National Functional Guidelines for Inorganic Superfund Methods Data Review (ISM02.4)

EPA Pesticide Factsheets

This document is designed to assist the reviewer in evaluating (a) whether the analytical data meet the technical and Quality Control (QC) criteria specified in the SOW, and (b) the usability and extent of bias of any data that do not meet these criteria.

Swimming Pools.

ERIC Educational Resources Information Center

Ministry of Housing and Local Government, London (England).

Technical and engineering data are set forth on the design and construction of swimming pools. Consideration is given to site selection, pool construction, the comparative merits of combining open air and enclosed pools, and alternative uses of the pool. Guidelines are presented regarding--(1) pool size and use, (2) locker and changing rooms, (3)…

Preliminary design specifications of a calcium model

NASA Technical Reports Server (NTRS)

1978-01-01

A list of objectives, requirements, and guidelines are given for a calcium model. Existing models are reviewed and evaluated in relation to the stated objectives and requirements. The reviewed models were either too abstract or apparently invalidated. A technical approach to the design of a desirable model is identified.

40 CFR 80.166 - Carburetor deposit control performance test and test fuel guidelines.

Code of Federal Regulations, 2014 CFR

2014-07-01

... demonstration of an additive's ability to control carburetor deposits. Examples of acceptable test procedures... Fuel Injector (PFI) Deposits in Vehicle Engines”, March 1, 1991, Section 2257, Title 13, California... Coordinating Research Council Program”, Robert Tupa et al., SAE Technical paper No. 890213, 1989. (3) “The...

40 CFR 80.166 - Carburetor deposit control performance test and test fuel guidelines.

Code of Federal Regulations, 2010 CFR

2010-07-01

... demonstration of an additive's ability to control carburetor deposits. Examples of acceptable test procedures... Fuel Injector (PFI) Deposits in Vehicle Engines”, March 1, 1991, Section 2257, Title 13, California... Coordinating Research Council Program”, Robert Tupa et al., SAE Technical paper No. 890213, 1989. (3) “The...

40 CFR 80.166 - Carburetor deposit control performance test and test fuel guidelines.

Code of Federal Regulations, 2013 CFR

2013-07-01

... demonstration of an additive's ability to control carburetor deposits. Examples of acceptable test procedures... Fuel Injector (PFI) Deposits in Vehicle Engines”, March 1, 1991, Section 2257, Title 13, California... Coordinating Research Council Program”, Robert Tupa et al., SAE Technical paper No. 890213, 1989. (3) “The...

40 CFR 80.166 - Carburetor deposit control performance test and test fuel guidelines.

Code of Federal Regulations, 2011 CFR

2011-07-01

... demonstration of an additive's ability to control carburetor deposits. Examples of acceptable test procedures... Fuel Injector (PFI) Deposits in Vehicle Engines”, March 1, 1991, Section 2257, Title 13, California... Coordinating Research Council Program”, Robert Tupa et al., SAE Technical paper No. 890213, 1989. (3) “The...

40 CFR 80.166 - Carburetor deposit control performance test and test fuel guidelines.

Code of Federal Regulations, 2012 CFR

2012-07-01

... demonstration of an additive's ability to control carburetor deposits. Examples of acceptable test procedures... Fuel Injector (PFI) Deposits in Vehicle Engines”, March 1, 1991, Section 2257, Title 13, California... Coordinating Research Council Program”, Robert Tupa et al., SAE Technical paper No. 890213, 1989. (3) “The...

Using Three-Dimensional Interactive Graphics To Teach Equipment Procedures.

ERIC Educational Resources Information Center

Hamel, Cheryl J.; Ryan-Jones, David L.

1997-01-01

Focuses on how three-dimensional graphical and interactive features of computer-based instruction can enhance learning and support human cognition during technical training of equipment procedures. Presents guidelines for using three-dimensional interactive graphics to teach equipment procedures based on studies of the effects of graphics, motion,…

Multi-scale soil salinity mapping and monitoring with proximal and remote sensing

USDA-ARS?s Scientific Manuscript database

This talk is part of a technical short course on “Soil mapping and process modelling at diverse scales”. In the talk, guidelines, special considerations, protocols, and strengths and limitations are presented for characterizing spatial and temporal variation in soil salinity at several spatial scale...

AN EVALUATION OF THE MODE OF ACTION FRAMEWORK FOR MUTAGENIC CARCINOGENSCASE STUDY: CYCLOPHOSPHAMIDE (Journal Article)

EPA Science Inventory

In response to the 2005 revised U.S Envrionmental Protection Agency (EPA) Cancer Guidelines, a Risk Assessment Forum’s Technical Panel is devising a strategy in which genetic toxicology data combined with other information are assessed to determine whether a carcinogen operates t...

Evaluation of Young Children for Early Intervention and Early Childhood Special Education.

ERIC Educational Resources Information Center

Allen, Diana

This technical assistance document provides guidelines for child assessment and eligibility determination for early intervention and early childhood special education programs in Oregon. An overview of the assessment process explains screening, eligibility evaluation, and assessment for the Individual Family Service Plan (IFSP). Legal requirements…

"Just the Answers, Please": Choosing a Web Search Service.

ERIC Educational Resources Information Center

Feldman, Susan

1997-01-01

Presents guidelines for selecting World Wide Web search engines. Real-life questions were used to test six search engines. Queries sought company information, product reviews, medical information, foreign information, technical reports, and current events. Compares performance and features of AltaVista, Excite, HotBot, Infoseek, Lycos, and Open…

Technical Manual for Batteries, Navy Lithium Safety Program Responsibilities and Procedures

DTIC Science & Technology

2004-08-19

lithium ion batteries and all equipment powered by lithium electrochemical power source(s) through all phases of the life of such systems. The purpose of this manual is to establish safety guidelines for the selection, design, testing, evaluation, use, packaging, storage, transportation and disposal of lithium

Differential prediction of FAA Academy performance on the basis of gender and written air traffic control specialist aptitude test scores.

DOT National Transportation Integrated Search

1996-04-01

The technical fairness of the written air traffic control specialist (ATCS) aptitude test battery was investigated within the framework of the Uniform Guidelines on Employee Selection Procedures (29 CFR 1607). First, the adverse impact of using a com...

Is Your School Librarian "Highly Qualified"?

ERIC Educational Resources Information Center

Kaplan, Allison G.

2007-01-01

The national guidelines for school library media programs clearly establish that the goal of the school library media specialist is to provide an instructional program that helps students and faculty become efficient and effective users of information. Along with running the library at a technical level as the program administrator, the school…

29 CFR 1607.6 - Use of selection procedures which have not been validated.

Code of Federal Regulations, 2010 CFR

2010-07-01

... circumstances in which a user cannot or need not utilize the validation techniques contemplated by these... which has an adverse impact, the validation techniques contemplated by these guidelines usually should be followed if technically feasible. Where the user cannot or need not follow the validation...

29 CFR 1607.6 - Use of selection procedures which have not been validated.

Code of Federal Regulations, 2014 CFR

2014-07-01

... circumstances in which a user cannot or need not utilize the validation techniques contemplated by these... which has an adverse impact, the validation techniques contemplated by these guidelines usually should be followed if technically feasible. Where the user cannot or need not follow the validation...

29 CFR 1607.6 - Use of selection procedures which have not been validated.

Code of Federal Regulations, 2011 CFR

2011-07-01

... circumstances in which a user cannot or need not utilize the validation techniques contemplated by these... which has an adverse impact, the validation techniques contemplated by these guidelines usually should be followed if technically feasible. Where the user cannot or need not follow the validation...

29 CFR 1607.6 - Use of selection procedures which have not been validated.

Code of Federal Regulations, 2013 CFR

2013-07-01

... circumstances in which a user cannot or need not utilize the validation techniques contemplated by these... which has an adverse impact, the validation techniques contemplated by these guidelines usually should be followed if technically feasible. Where the user cannot or need not follow the validation...

29 CFR 1607.6 - Use of selection procedures which have not been validated.

Code of Federal Regulations, 2012 CFR

2012-07-01

... circumstances in which a user cannot or need not utilize the validation techniques contemplated by these... which has an adverse impact, the validation techniques contemplated by these guidelines usually should be followed if technically feasible. Where the user cannot or need not follow the validation...

Installation, care, and maintenance of wood shake and shingle siding

Treesearch

Jack Dwyer; Tony Bonura; Arnie Nebelsick; Sam Williams; Christopher G. Hunt

2011-01-01

This article gives general guidelines for selection, installation, finishing, and maintenance of wood shakes and shingles. The authors gathered information from a variety of sources: research publications on wood finishing, technical data sheets from paint manufacturers, installation instructions for shake and shingle siding, and interviews with experts having...

26 CFR 601.901 - Missing children shown on penalty mail.

Code of Federal Regulations, 2014 CFR

2014-04-01

... those which have been updated to reflect a missing child's current age through computer enhancement... shelf-life guideline. (d) Reports and contact official. IRS shall compile and submit to OJJDP reports on... Division, Technical Publications Branch, OP:FS:FP:P:3, Room 5613, Internal Revenue Service, 1111...

26 CFR 601.901 - Missing children shown on penalty mail.

Code of Federal Regulations, 2010 CFR

2010-04-01

... those which have been updated to reflect a missing child's current age through computer enhancement... shelf-life guideline. (d) Reports and contact official. IRS shall compile and submit to OJJDP reports on... Division, Technical Publications Branch, OP:FS:FP:P:3, Room 5613, Internal Revenue Service, 1111...

26 CFR 601.901 - Missing children shown on penalty mail.

Code of Federal Regulations, 2011 CFR

2011-04-01

... those which have been updated to reflect a missing child's current age through computer enhancement... shelf-life guideline. (d) Reports and contact official. IRS shall compile and submit to OJJDP reports on... Division, Technical Publications Branch, OP:FS:FP:P:3, Room 5613, Internal Revenue Service, 1111...

26 CFR 601.901 - Missing children shown on penalty mail.

Code of Federal Regulations, 2013 CFR

2013-04-01

... those which have been updated to reflect a missing child's current age through computer enhancement... shelf-life guideline. (d) Reports and contact official. IRS shall compile and submit to OJJDP reports on... Division, Technical Publications Branch, OP:FS:FP:P:3, Room 5613, Internal Revenue Service, 1111...

26 CFR 601.901 - Missing children shown on penalty mail.

Code of Federal Regulations, 2012 CFR

2012-04-01

... those which have been updated to reflect a missing child's current age through computer enhancement... shelf-life guideline. (d) Reports and contact official. IRS shall compile and submit to OJJDP reports on... Division, Technical Publications Branch, OP:FS:FP:P:3, Room 5613, Internal Revenue Service, 1111...

Legionellosis on the Rise: A Review of Guidelines for Prevention in the United States

PubMed Central

Parr, Alyssa; Whitney, Ellen A.; Berkelman, Ruth L.

2015-01-01

Context: Reported cases of legionellosis more than tripled between 2001 and 2012 in the United States. The disease results primarily from exposure to aerosolized water contaminated with Legionella. Objective: To identify and describe policies and guidelines for the primary prevention of legionellosis in the US. Design: An Internet search for Legionella prevention guidelines in the United States at the federal and state levels was conducted from March to June 2012. Local government agency guidelines and guidelines from professional organizations that were identified in the initial search were also included. Setting: Federal, state, and local governing bodies and professional organizations. Results: Guidelines and regulations for the primary prevention of legionellosis (ie, Legionnaires' disease and Pontiac fever) have been developed by various public health and other government agencies at the federal, state, and local levels as well as by professional organizations. These guidelines are similar in recommending maintenance of building water systems; federal and other guidelines differ in the population/institutions targeted, the extent of technical detail, and support of monitoring water systems for levels of Legionella contamination. Conclusions: Legionellosis deserves a higher public health priority for research and policy development. Guidance across public health agencies for the primary prevention of legionellosis requires strengthening as this disease escalates in importance as a cause of severe morbidity and mortality. We recommend a formal and comprehensive review of national public health guidelines for prevention of legionellosis. PMID:25203696

Insight into the Chemistry Skills Gap: The Duality between Expected and Desired Skills

ERIC Educational Resources Information Center

Kondo, Anne E.; Fair, Justin D.

2017-01-01

Results from an employer survey that examines the skills gap that exists for students majoring in chemistry are presented. Employers expect candidates with technical abilities but desire those who possess strong interprofessional skills. Although employers do not expect students to have had explicit teaching and application of interprofessional…

USSR and Eastern Europe Scientific Abstracts, Electronics and Electrical Engineering, Number 41

DTIC Science & Technology

1978-08-08

ELEKTRICHESKIYE STANTSII In Russian No 3, Mar 78 pp 70-71 KUZNETSOV, Vi P., Z0B0LÖTNIK0V, V. I. and MAKEYEV , V. P., engineers, Doltekhenergo...after completion 25 Mar 76 LEYTMAN, MIKHAIL BORISOVICH, candidate in technical sciences, dotsent, Smolensk Affiliate of Moscow Power Engineering

Testing Teacher Candidates: The Role of Licensure Tests in Improving Teacher Quality.

ERIC Educational Resources Information Center

Mitchell, Karen J., Ed.; Robinson, David Z., Ed.; Plake, Barbara S., Ed.; Knowles, Kaeli T., Ed.

This book examines the appropriateness and technical quality of teacher licensure tests currently in use, evaluating teacher licensure tests and examining the use of tests to hold states and institutions of higher education accountable for the quality of teacher preparation and licensure. It also suggests alternatives for developing and assessing…

32 CFR 705.6 - Releasing public information material to the media.

Code of Federal Regulations, 2011 CFR

2011-07-01

... for questions without specific subject matter in mind, but the press should be clearly informed of the... should be present. (iv) Official spokesmen will be prepared to answer questions in a frank and candid... questions in advance. If this is considered advisable, as in cases where highly technical answers may be...

32 CFR 705.6 - Releasing public information material to the media.

Code of Federal Regulations, 2010 CFR

2010-07-01

... for questions without specific subject matter in mind, but the press should be clearly informed of the... should be present. (iv) Official spokesmen will be prepared to answer questions in a frank and candid... questions in advance. If this is considered advisable, as in cases where highly technical answers may be...

Leadership Assessment and Training Simulation; Field Application and Faculty Training System. Final Technical Report.

ERIC Educational Resources Information Center

Hunsaker, Phillip L.

In previous research a pilot simulation was developed for use by Reserve Officers Training Corps (ROTC) units in assessing leadership potential of officer candidates in turbulent-field environments. Peer and instructor rating forms were also developed for evaluation of leadership, decision style, ability to cope with stress, and interpersonal…

Clinical proteomic biomarkers: relevant issues on study design & technical considerations in biomarker development

PubMed Central

2014-01-01

Biomarker research is continuously expanding in the field of clinical proteomics. A combination of different proteomic–based methodologies can be applied depending on the specific clinical context of use. Moreover, current advancements in proteomic analytical platforms are leading to an expansion of biomarker candidates that can be identified. Specifically, mass spectrometric techniques could provide highly valuable tools for biomarker research. Ideally, these advances could provide with biomarkers that are clinically applicable for disease diagnosis and/ or prognosis. Unfortunately, in general the biomarker candidates fail to be implemented in clinical decision making. To improve on this current situation, a well-defined study design has to be established driven by a clear clinical need, while several checkpoints between the different phases of discovery, verification and validation have to be passed in order to increase the probability of establishing valid biomarkers. In this review, we summarize the technical proteomic platforms that are available along the different stages in the biomarker discovery pipeline, exemplified by clinical applications in the field of bladder cancer biomarker research. PMID:24679154

[Evaluation of tools for the implementation of clinical practice guidelines on sexually transmitted infections].

PubMed

Moreno, Jaime Hernán Rodríguez; Romero Vergara, Antonio José; De Moya, Danilo De Jesús De Alba; Jaramillo Rojas, Hernán Javier; Díaz Rojas, Claudia Milena; Ciapponi, Agustín

2017-05-25

Determine the acceptability, perceived usefulness, and adoption of implementation tools and technical assistance provided by the Health Technology Assessment Institute (IETS) in hospitals in two regions of Colombia. Assistance was provided for implementation of clinical practice guidelines (CPGs) in 24 hospitals (17 in Antioquia and seven in Cundinamarca) in areas with high prevalence of sexually transmitted infections, and for use of the implementation tools. Health professionals were given surveys and medical specialists were interviewed. Overall, 86% of respondents are familiar with the GPGs, 86% with the tracer recommendations, 79% with the interactive flow charts, and 82% with the evidence sheets, while 41% never used the implementation tools. Of the respondents who used the tools, 55% did so on their work computer, while 24% used their personal telephone. The most useful tools were the evidence sheets and flow charts (98%) and the tracer recommendations (92%). The least useful were the budgetary impact tools (81%). The implementation tools and technical assistance provided in hospitals in two regions of Colombia are perceived as useful and acceptable, although the degree of implementation is low. The findings of this research will help the different actors, such as the Ministry of Health and Social Protection, the IETS, and the Administrative Department of Science, Technology and Innovation (Colciencias), among others, improve their programs for the implementation of clinical practice guidelines.

Heat engine development for solar thermal power systems

NASA Astrophysics Data System (ADS)

Pham, H. Q.; Jaffe, L. D.

The parabolic dish solar collector systems for converting sunlight to electrical power through a heat engine will, require a small heat engine of high performance long lifetime to be competitive with conventional power systems. The most promising engine candidates are Stirling, high temperature Brayton, and combined cycle. Engines available in the current market today do not meet these requirements. The development of Stirling and high temperature Brayton for automotive applications was studied which utilizes much of the technology developed in this automotive program for solar power engines. The technical status of the engine candidates is reviewed and the components that may additional development to meet solar thermal system requirements are identified.

Evaluation of pediatric cochlear implant care throughout Europe: Is European pediatric cochlear implant care performed according to guidelines?

PubMed

Bruijnzeel, Hanneke; Bezdjian, Aren; Lesinski-Schiedat, Anke; Illg, Angelika; Tzifa, Konstance; Monteiro, Luisa; Volpe, Antonio Della; Grolman, Wilko; Topsakal, Vedat

2017-11-01

International guidelines indicate that children with profound hearing loss should receive a cochlear implant (CI) soon after diagnosis in order to optimize speech and language rehabilitation. Although prompt rehabilitation is encouraged by current guidelines, delays in cochlear implantation are still present. This study investigated whether European countries establish timely pediatric CI care based on epidemiological, commercial, and clinical data. An estimation of the number of pediatric CI candidates in European countries was performed and compared to epidemiological (Euro-CIU), commercial (Cochlear ® ), and clinical (institutional) age-at-implantation data. The ages at implantation of pediatric patients in eight countries (the Netherlands, Belgium, Germany, the United Kingdom, France, Turkey, Portugal, and Italy) between 2005 and 2015 were evaluated. From 2010 onwards, over 30% of the pediatric CI candidates were implanted before 24 months of age. Northern European institutions implanted children on average around 12 months of age, whereas southern European institutions implanted children after 18 months of age. The Netherlands and Germany implanted earliest (between 6 and 11 months). Implemented newborn hearing screening programs and reimbursement rates of CIs vary greatly within Europe due to local, social, financial, and political differences. However, internationally accepted recommendations are applicable to this heterogeneous European CI practice. Although consensus on early pediatric cochlear implantation exists, this study identified marked delays in European care. Regardless of the great heterogeneity in European practice, reasons for latency should be identified on a national level and possibilities to prevent avoidable future implantation delays should be explored to provide national recommendations.

A critical appraisal of guidelines used for management of severe acute malnutrition in South Africa's referral system.

PubMed

Mambulu-Chikankheni, Faith Nankasa; Eyles, John; Eboreime, Ejemai Amaize; Ditlopo, Prudence

2017-10-18

Focusing on healthcare referral processes for children with severe acute malnutrition (SAM) in South Africa, this paper discusses the comprehensiveness of documents (global and national) that guide the country's SAM healthcare. This research is relevant because South African studies on SAM mostly examine the implementation of WHO guidelines in hospitals, making their technical relevance to the country's lower level and referral healthcare system under-explored. To add to both literature and methods for studying SAM healthcare, we critically appraised four child healthcare guidelines (global and national) and conducted complementary expert interviews (n = 5). Combining both methods enabled us to examine the comprehensiveness of the documents as related to guiding SAM healthcare within the country's referral system as well as the credibility (rigour and stakeholder representation) of the guideline documents' development process. None of the guidelines appraised covered all steps of SAM referrals; however, each addressed certain steps thoroughly, apart from transit care. Our study also revealed that national documents were mostly modelled after WHO guidelines but were not explicitly adapted to local context. Furthermore, we found most guidelines' formulation processes to be unclear and stakeholder involvement in the process to be minimal. In adapting guidelines for management of SAM in South Africa, it is important that local context applicability is taken into consideration. In doing this, wider stakeholder involvement is essential; this is important because factors that affect SAM management go beyond in-hospital care. Community, civil society, medical and administrative involvement during guideline formulation processes will enhance acceptability and adherence to the guidelines.

Planning practice in support of economically and environmentally sustainable roads in floodplains: the case of the Mekong delta floodplains.

PubMed

Douven, Wim; Buurman, Joost

2013-10-15

Road development in relatively undisturbed floodplain systems, such as the floodplains of the Mekong River, will impact hydraulics and interrupt the natural flow of water. This affects the ecology and environment, and the livelihoods of people who depend on fishing and agriculture. On the other hand, floods can severely damage road infrastructure in years with large floods and can cause high annual maintenance costs. Improving road development practices in floodplains is a complex, multidimensional task involving hydraulic and geotechnical analysis, ecosystem analysis, socio-economic analysis, policy analysis, etc. This paper analyses the planning practice of road development and rehabilitation and how this practice can be improved in support of economically and environmentally sustainable roads in floodplains. It is concluded that although ample technical, planning and environmental assessment guidelines exist, guidelines need updating to address cumulative impacts at floodplain level and factors hampering the implementation in guidelines should be addressed in the guideline design (process). Copyright © 2013 Elsevier Ltd. All rights reserved.

WHO Expert Committee on Specifications for Pharmaceutical Preparations. Fiftieth report.

PubMed

2016-01-01

The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensus-building process. The following new guidelines were adopted and recommended for use. Good pharmacopoeial practices; FIP-WHO technical guidelines: points to consider in the provision by health-care professionals of children-specific preparations that are not available as authorized products; Guidance on good manufacturing practices for biological products; Guidance on good manufacturing practices: inspection report, including Appendix 1: Model inspection report; Guidance on good data and record management practices; Good trade and distribution practices for starting materials; Guidelines on the conduct of surveys of the quality of medicines; Collaborative procedure between the World Health Organization (WHO) prequalification team and national regulatory authorities in the assessment and accelerated national registration of WHO-prequalified pharmaceutical products and vaccines; Guidance for organizations performing in vivo bioequivalence studies; and World Health Organization (WHO) general guidance on variations to multisource pharmaceutical products.

The Asthma Kiosk: A Patient-centered Technology for Collaborative Decision Support in the Emergency Department

PubMed Central

Porter, Stephen C.; Cai, Zhaohui; Gribbons, William; Goldmann, Donald A.; Kohane, Isaac S.

2004-01-01

The authors report on the development and evaluation of a novel patient-centered technology that promotes capture of critical information necessary to drive guideline-based care for pediatric asthma. The design of this application, the asthma kiosk, addresses five critical issues for patient-centered technology that promotes guideline-based care: (1) a front-end mechanism for patient-driven data capture, (2) neutrality regarding patients' medical expertise and technical backgrounds, (3) granular capture of medication data directly from the patient, (4) formal algorithms linking patient-level semantics and asthma guidelines, and (5) output to both patients and clinical providers regarding best practice. The formative evaluation of the asthma kiosk demonstrates its ability to capture patient-specific data during real-time care in the emergency department (ED) with a mean completion time of 11 minutes. The asthma kiosk successfully links parents' data to guideline recommendations and identifies data critical to health improvements for asthmatic children that otherwise remains undocumented during ED-based care. PMID:15298999

Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project.

PubMed

2003-02-01

International interest in clinical practice guidelines has never been greater but many published guidelines do not meet the basic quality requirements. There have been renewed calls for validated criteria to assess the quality of guidelines. To develop and validate an international instrument for assessing the quality of the process and reporting of clinical practice guideline development. The instrument was developed through a multi-staged process of item generation, selection and scaling, field testing, and refinement procedures. 100 guidelines selected from 11 participating countries were evaluated independently by 194 appraisers with the instrument. Following refinement the instrument was further field tested on three guidelines per country by a new set of 70 appraisers. The final version of the instrument contained 23 items grouped into six quality domains with a 4 point Likert scale to score each item (scope and purpose, stakeholder involvement, rigour of development, clarity and presentation, applicability, editorial independence). 95% of appraisers found the instrument useful for assessing guidelines. Reliability was acceptable for most domains (Cronbach's alpha 0.64-0.88). Guidelines produced as part of an established guideline programme had significantly higher scores on editorial independence and, after the publication of a national policy, had significantly higher quality scores on rigour of development (p<0.005). Guidelines with technical documentation had higher scores on that domain (p<0.0001). This is the first time an appraisal instrument for clinical practice guidelines has been developed and tested internationally. The instrument is sensitive to differences in important aspects of guidelines and can be used consistently and easily by a wide range of professionals from different backgrounds. The adoption of common standards should improve the consistency and quality of the reporting of guideline development worldwide and provide a framework to encourage international comparison of clinical practice guidelines.

Uncertainty Estimation Cheat Sheet for Probabilistic Risk Assessment

NASA Technical Reports Server (NTRS)

Britton, Paul; Al Hassan, Mohammad; Ring, Robert

2017-01-01

Quantitative results for aerospace engineering problems are influenced by many sources of uncertainty. Uncertainty analysis aims to make a technical contribution to decision-making through the quantification of uncertainties in the relevant variables as well as through the propagation of these uncertainties up to the result. Uncertainty can be thought of as a measure of the 'goodness' of a result and is typically represented as statistical dispersion. This paper will explain common measures of centrality and dispersion; and-with examples-will provide guidelines for how they may be estimated to ensure effective technical contributions to decision-making.

Technical analysis of US Army Weapons Systems and related advanced technologies of military interest. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1991-06-14

This report summarizes the activities and accomplishments of an US Army technology security project designed to identify and develop effective policy guidelines for militarily critical technologies in specific Army systems and in broad generic technology areas of military interest, Individual systems analyses are documented in separate Weapons Systems Technical Assessments (WSTAs) and the general generic technology areas are evaluated in the Advanced Technology Assessment Reports (ATARs), However, specific details of these assessments are not addressed here, only recommendations regarding aspects of the defined approach, methodology, and format are provided and discussed.

General requirements to implement the personal dose equivalent Hp(10) in Brazil

NASA Astrophysics Data System (ADS)

Gomes Lopes, Amanda; Da Silva, Francisco Cesar Augusto

2018-03-01

To update the dosimetry quantity with the international community, Brazil is changing the Individual Dose (Hx) to the Personal Dose Equivalent Hp(10). A bibliographical survey on the technical and administrative requirements of nine countries that use Hp(10) was carried out to obtain the most relevant ones. All of them follow IEC and ISO guidelines for technical requirements, but administrative requirements change from country to country. Based on countries experiences, this paper presents a list of important general requirements to implement Hp(10) and to prepare the Brazilian requirements according to the international scientific community.

Guidelines for Home Energy Professionals Project: Multifamily Job Task Analyses Needs Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dirr, N.; Hepinstall, D.; Douglas, M.

This report describes the efforts carried out to determine whether there is a need to develop separate, multifamily-specific JTAs for the four proposed job categories. The multifamily SWS market committee considered these job designations to be the best candidates for developing JTAs and certification blueprints, as well as having the greatest potential for promoting job growth in the multifamily home performance industry.