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Sample records for case history study

  1. Curriculum Formation: A Case Study from History

    ERIC Educational Resources Information Center

    Shay, Suellen

    2011-01-01

    Drawing on the work of Bernstein and Maton and using a case-study approach, this study explores the formation of an undergraduate history curriculum at the University of Cape Town. This article focuses on two periods of curriculum formation referred to as history as canon and history as social science. With respect to these two curriculum periods…

  2. A History and Case Study at a Selected Tribal College

    ERIC Educational Resources Information Center

    Oltrogge, Micheal P.

    2010-01-01

    "A History and Case Study at a Selected Tribal College" focuses on a tribally chartered two-year institution of higher education. The selected Tribal College serves Native American and non-Native American populations on two separate and distinct reservations and one urban location. This study surveys the history to answer basic foundational and…

  3. A Pedagogical Trebuchet: A Case Study in Experimental History and History Pedagogy

    ERIC Educational Resources Information Center

    Brice, Lee L.; Catania, Steven

    2012-01-01

    A common problem history teachers face regardless of their field of specialization is how to help students find answers to the most difficult historical questions, those for which the sources are unavailable or inaccessible, and teach them to do so in a methodologically valid manner. This article presents a case study which shows how a project in…

  4. A Pedagogical Trebuchet: A Case Study in Experimental History and History Pedagogy

    ERIC Educational Resources Information Center

    Brice, Lee L.; Catania, Steven

    2012-01-01

    A common problem history teachers face regardless of their field of specialization is how to help students find answers to the most difficult historical questions, those for which the sources are unavailable or inaccessible, and teach them to do so in a methodologically valid manner. This article presents a case study which shows how a project in…

  5. Metric usage study: A look at 6 case histories

    NASA Astrophysics Data System (ADS)

    This study was prepared to describe the metric experiences, good as well as bad, of a number of firms representing a cross-section of American business and industry. Their experiences show that there are problems as well as opportunities inherent in metric conversion. The six case histories presented in this publication reflect the trend, the drawbacks, and the merits of metric usage in the private sector. The United States Metric Board was created by Congress to plan and coordinate the increasing voluntary use of the metric system in the United States. This study has been developed as part of the Board's public awareness and education program. The six firms that were studied are Black and Webster, Samuel Cabot, Inc., Caterpillar Tractor, National Distillers Company, Levi Strauss & Co., and Inland Steel Company in the preparation of this publication.

  6. Haematopoietic cancer and medical history: a multicentre case control study

    PubMed Central

    Vineis, P.; Crosignani, P.; Sacerdote, C.; Fontana, A.; Masala, G.; Miligi, L.; Nanni, O.; Ramazzotti, V.; Rodella, S.; Stagnaro, E.; Tumino, R.; Vigano, C.; Vindigni, C.; Costantini, A. S.

    2000-01-01

    BACKGROUND—Viruses (such as Epstein-Barr virus) and pathological conditions (mainly involving immunosuppression) have been shown to increase the risk of haematolymphopoietic malignancies. Other associations (diabetes, tonsillectomy, autoimmune diseases) have been inconsistently reported.
METHODS—The association between different haematolymphopoietic malignancies (lymphomas, myelomas and leukaemias) and the previous medical history has been studied in a population-based case-control investigation conducted in Italy, based on face to face interviews to 2669 cases and 1718 population controls (refusal rates 10% and 19%, respectively). Controls were a random sample of the general population.
RESULTS—Previous findings were confirmed concerning the association between non-Hodgkin's lymphoma (NHL) and lupus erythematosus (odds ratio, OR=8.4; 95% CI 1.6, 45), tuberculosis (OR=1.6; 1.05, 2.5) and hepatitis (1.8; 1.4, 2.3). An association was found also between NHL and maternal (OR=2.8; 1.1, 6.9) or paternal tuberculosis (OR=1.7; 0.7, 3.9). Odds ratios of 4.0 (1.4, 11.8) and 4.4 (1.1, 6.6) were detected for the association between NHL and Hodgkin's disease, respectively, and previous infectious mononucleosis, but recall bias cannot be ruled out. No association was found with diabetes, tonsillectomy and adenoidectomy. An association with malaria at young age and "low grade" lymphatic malignancies is suggested. One interesting finding was the observation of four cases of poliomyelitis among NHL patients, one among Hodgkin's disease and one among myeloid leukaemia patients, compared with none among the controls (Fisher's exact test for NHL and Hodgkin's disease, p= 0.03, one tail).
CONCLUSIONS—Some of these findings are confirmatory of previous evidence. Other observations, such as the putative role of the polio virus and of malaria are new. A unifying theory on the mechanisms by which previous medical history may increase the risk of

  7. Case history

    SciTech Connect

    Garelick, B. )

    1988-01-01

    Recycling offers a means by which hazardous materials can be kept from entering the environment. In addition to its environmental benefits, the recycling of certain byproducts, sludges, and spent materials generated from industrial processes was viewed by some as a means for exclusion from regulation under RCRA. Under EPA's 19 May 1980 regulations, non-listed wastes that were recycled were not regulated. Consequently, many activities called recycling occurred but were viewed by EPA as analogous to land disposal or incineration rather than recycling. Ultimately, these issues served as an impetus to reconsider the recycling provisions of the RCRA regulations; in particular, EPA undertook an extensive rewrite of the definition of solid waste. This paper explores a case of a proposed modernization to USS-POSCO's steel finishing plant in Pittsburg, California, and how it has been affected by EPA's definition of solid waste. The modernization would include a closed-loop facility in which the spent pickle liquor would be processed, resulting in hydrochloric acid that would be reused in the pickling lines. The ferric oxide produced through this process would be removed and sold.

  8. The Path of History: Narrative Analysis of History Textbooks--A Case Study of Belgian History Textbooks (1945-2004)

    ERIC Educational Resources Information Center

    Vanhulle, Bert

    2009-01-01

    The philosophical background of the subject history in secondary education has been mainly addressed through research based on "obvious" source types (curricula, discussions in committees or journals, ...). This article proposes a narrative method of analysing history textbooks in order to study the underlining historical philosophy of…

  9. Doing Local History: A Case Study of New Brunswick, New Jersey

    ERIC Educational Resources Information Center

    Marino, Michael P.; Crocco, Margaret Smith

    2012-01-01

    This article provides a methodology that teachers can use to incorporate themes and ideas related to local history in their classrooms. Using the city of New Brunswick, New Jersey as a case study, the article offers different approaches that allow local history to be connected to wider themes in American history. The focus here on a small,…

  10. The Mystery of the Blue Death: A Case Study in Epidemiology and the History of Science

    ERIC Educational Resources Information Center

    Muench, Susan Bandoni

    2009-01-01

    This case study introduces students to John Snow, considered to be one of the founders of both epidemiology and anesthesiology, and a remarkable figure in the history of science. Although historical case studies are often less popular with students than contemporary issues (Herreid 1998), a number of aspects of this case make it attractive to…

  11. The Mystery of the Blue Death: A Case Study in Epidemiology and the History of Science

    ERIC Educational Resources Information Center

    Muench, Susan Bandoni

    2009-01-01

    This case study introduces students to John Snow, considered to be one of the founders of both epidemiology and anesthesiology, and a remarkable figure in the history of science. Although historical case studies are often less popular with students than contemporary issues (Herreid 1998), a number of aspects of this case make it attractive to…

  12. Assessing Investigative Skills in History: A Case Study from Scotland

    ERIC Educational Resources Information Center

    Hillis, Peter

    2005-01-01

    Recent changes in the history syllabi stress the importance of developing an investigative/enquiry method of learning involving the framing of questions, subsequent research, and the presentation of findings. Scotland has made several attempts to assess not only the end result (the paper) but also the process itself and now uses an extended essay…

  13. Case studies in cholera: lessons in medical history and science.

    PubMed Central

    Kavic, S. M.; Frehm, E. J.; Segal, A. S.

    1999-01-01

    Cholera, a prototypical secretory diarrheal disease, is an ancient scourge that has both wrought great suffering and taught many valuable lessons, from basic sanitation to molecular signal transduction. Victims experience the voluminous loss of bicarbonate-rich isotonic saline at a rate that may lead to hypovolemic shock, metabolic acidosis, and death within afew hours. Intravenous solution therapy as we know it was first developed in an attempt to provide life-saving volume replacement for cholera patients. Breakthroughs in epithelial membrane transport physiology, such as the discovery of sugar and salt cotransport, have paved the way for oral replacement therapy in areas of the world where intravenous replacement is not readily available. In addition, the discovery of the cholera toxin has yielded vital information about toxigenic infectious diseases, providing a framework in which to study fundamental elements of intracellular signal transduction pathways, such as G-proteins. Cholera may even shed light on the evolution and pathophysiology of cystic fibrosis, the most commonly inherited disease among Caucasians. The goal of this paper is to review, using case studies, some of the lessons learned from cholera throughout the ages, acknowledging those pioneers whose seminal work led to our understanding of many basic concepts in medical epidemiology, microbiology, physiology, and therapeutics. PMID:11138935

  14. Conflict Resolution and History: The War with Mexico as a Case Study.

    ERIC Educational Resources Information Center

    Gardner, Arlene L.; Chambers, John W.

    2001-01-01

    Discusses how to incorporate conflict resolution into history focusing on the Conflict Resolution in History project. Provides a case study depicting how to use conflict resolution by presenting a lesson plan exploring the 1846 War between the United States and Mexico. (CMK)

  15. Association between family history and herpes zoster: a case-control study.

    PubMed

    Ansar, Akram; Farshchian, Mahmood; Ghasemzadeh, Mostafa; Sobhan, Mohammad Reza

    2014-01-01

    There are many risk factors besides age and immune suppression for herpes zoster. Family history as a risk factor is suggested in some recent studies. The aim of this study was to evaluate the association between herpes zoster and family history. This case-control study was undertaken in Farshchian Hospital, Hamadan, Iran. "Case group" included patients with confirmed diagnosis of herpes zoster. "Control group" was chosen among other dermatologic patients or their companions without any history of herpes zoster. Immune deficiency was the main excluding criteria. Information about age, gender, dermatome involved (only in patient group), history of chronic dermatologic or systemic diseases and family history of herpes zoster was asked using special questionnaires. Case and control groups included 217 and 200 participants respectively. Mean age of cases and controls was 49.08±15.59 and 49.96±15.54 years old respectively (P=0.936). 53.5% of cases and 54.5% of controls were women (P=0.845). Most frequent dermatomes involved in patients were thoracic (85/217; 39.25%) and cervical dermatomes (55/217; 25.3%). Frequency of herpes zoster in first-degree blood relatives in cases and controls was 65/217 (30%) and 16/200 (8%) respectively (OR=4.91; 95% CI: 2.73, 8.85; P=0.001). Our findings indicated a significantly higher proportion of patients with family history of herpes zoster comparing to controls. This study confirms family history as a risk factor for herpes zoster. Therefore, the old patients with positive family history of herpes zoster may be appropriate candidates for vaccination with Zostavax. However, more evidence based on large cohort studies in needed to confirm our findings.

  16. Studying Epistemic Cognition in the History Classroom: Cases of Teaching and Learning to Think Historically

    ERIC Educational Resources Information Center

    Maggioni, Liliana

    2010-01-01

    Building on the literature on epistemic cognition, epistemic beliefs, and historical thinking, three class-level case studies were conducted to investigate features of historical thinking and history-specific epistemic beliefs of high-school students and their teachers. These cases also considered teachers' pedagogical practices and the potential…

  17. JSTOR: A Case Study in the Recent History of Scholarly Communications

    ERIC Educational Resources Information Center

    Schonfeld, Roger C.

    2005-01-01

    Purpose: To argue for the consideration from an historical perspective of technology-enabled changes in higher education. Design/methodology/approach: Uses examples from the author's history of JSTOR as a case study. Findings: That the case of JSTOR offers evidence that technology-enabled changes in higher education will have historical interest.…

  18. JSTOR: A Case Study in the Recent History of Scholarly Communications

    ERIC Educational Resources Information Center

    Schonfeld, Roger C.

    2005-01-01

    Purpose: To argue for the consideration from an historical perspective of technology-enabled changes in higher education. Design/methodology/approach: Uses examples from the author's history of JSTOR as a case study. Findings: That the case of JSTOR offers evidence that technology-enabled changes in higher education will have historical interest.…

  19. A Case History and Comparative Study of a Multiple Personality.

    ERIC Educational Resources Information Center

    Boor, Myron

    The study of multiple personality is important because this disorder is severely disruptive to the individual and because further insights into other behavior disorders and the development of normal personality and behavioral functioning may emerge. A 26-year-old female experienced a conscious personality which determined the extent to which both…

  20. Accurate patient history contributes to differentiating diabetes insipidus: a case study.

    PubMed

    Olson, DaiWai M; Meek, LorieAnn G; Lynch, John R

    2004-08-01

    This case study highlights the important contribution of nursing in obtaining an accurate health history. The case discussed herein initially appeared to be neurogenic diabetes insipidus (DI) secondary to a traumatic brain injury. The nursing staff, by reviewing the patient's health history with his family, discovered a history of polydipsia and long-standing lithium use. Lithium is implicated in drug-induced nephrogenic DI, and because the patient had not received lithium since being admitted to the hospital, his treatment changed to focus on nephrogenic DI. By combining information from the patient history, the physical examination, and radiologic and laboratory studies, the critical care team demonstrated that the patient had been self-treating his lithium-induced nephrogenic DI and developed neurogenic DI secondary to brain trauma. Thus successful treatment required that nephrogenic and neurogenic DI be treated concomitantly.

  1. Rh factor, family history and risk of breast cancer: a case-control study in Uruguay.

    PubMed

    Ronco, Alvaro L; Stoll, Mario; De Stéfani, Eduardo; Maisonneuve, Juan E; Mendoza, Beatriz A; Deneo-Pellegrini, Hugo

    2009-01-01

    To explore possible relationships among blood factors, family history of breast cancer (BC) and the risk of the disease, a case-control study was carried out in Montevideo, Uruguay. Eight hundred and one patients were interviewed, including 252 certified cases of BC and 549 frequency-matched controls. Blood groups (ABO, Rh) were obtained from medical records. Multivariate analyses were performed, adjusting for age, selected menstrual and reproductive factors, and family history of BC as well as of other cancers. We found that the absence of Rh factor (Rh-) was positively associated with the risk of BC (adjusted Odds Ratio [OR]=1.49, 95% Confidence Interval [95% CI] 1.05-2.11). Stratified analyses by family history of BC showed a strong association for Rh- with a positive history of first degree relatives (OR=3.17, 95% CI 1.06-9.47). Also stratified analyses by family history of other cancers showed a positive association for Rh- with a positive history of first degree relatives (OR=2.08, 95% CI 1.05-4.11). Regarding the implications of an inherited factor like Rh and its associations with the family history of BC, it might increase the probability to generate high-risk individuals if further studies confirm the present preliminary findings.

  2. The Changing Nature of Church College Relations: A History and Case Study of Concordia University Texas

    ERIC Educational Resources Information Center

    Kirk, Kristi K.

    2013-01-01

    This study provides a history and case study of Concordia University Texas (CTX). There has been a gap in the scholarly research literature regarding how and to what extent Concordia Texas mirrors the path of other denominational colleges and universities in terms of relationship to their founding church bodies. Therefore, the purpose of this…

  3. The Utilization of Local History in Teaching American Religious History: A Gilded Age and Progressive Era North Dakota Case Study

    ERIC Educational Resources Information Center

    Price, Christopher Neal

    2013-01-01

    Teachers of college-level courses on American religious history generally leave out the importance of local and regional histories when telling the story of religion in America. The study of local history provides a fertile ground for understanding broad national trends in a local context. This dissertation focuses upon a little-studied religious…

  4. The Utilization of Local History in Teaching American Religious History: A Gilded Age and Progressive Era North Dakota Case Study

    ERIC Educational Resources Information Center

    Price, Christopher Neal

    2013-01-01

    Teachers of college-level courses on American religious history generally leave out the importance of local and regional histories when telling the story of religion in America. The study of local history provides a fertile ground for understanding broad national trends in a local context. This dissertation focuses upon a little-studied religious…

  5. History Places: A Case Study for Relational Database and Information Retrieval System Design

    ERIC Educational Resources Information Center

    Hendry, David G.

    2007-01-01

    This article presents a project-based case study that was developed for students with diverse backgrounds and varied inclinations for engaging technical topics. The project, called History Places, requires that student teams develop a vision for a kind of digital library, propose a conceptual model, and use the model to derive a logical model and…

  6. History Places: A Case Study for Relational Database and Information Retrieval System Design

    ERIC Educational Resources Information Center

    Hendry, David G.

    2007-01-01

    This article presents a project-based case study that was developed for students with diverse backgrounds and varied inclinations for engaging technical topics. The project, called History Places, requires that student teams develop a vision for a kind of digital library, propose a conceptual model, and use the model to derive a logical model and…

  7. Teaching History with Comic Books: A Case Study of Violence, War, and the Graphic Novel

    ERIC Educational Resources Information Center

    Decker, Alicia C.; Castro, Mauricio

    2012-01-01

    In this essay, the authors present a case study that demonstrates how graphic novels can be utilized in the history classroom. More specifically, they discuss the benefits (and challenges) of using comic books to teach undergraduates about war and violence. While much of their discussion focuses on the historical particularities of Uganda, their…

  8. Teaching History with Comic Books: A Case Study of Violence, War, and the Graphic Novel

    ERIC Educational Resources Information Center

    Decker, Alicia C.; Castro, Mauricio

    2012-01-01

    In this essay, the authors present a case study that demonstrates how graphic novels can be utilized in the history classroom. More specifically, they discuss the benefits (and challenges) of using comic books to teach undergraduates about war and violence. While much of their discussion focuses on the historical particularities of Uganda, their…

  9. Taxonomy and why history of science matters for science: a case study.

    PubMed

    Hamilton, Andrew; Wheeler, Quentin D

    2008-06-01

    The history of science often has difficulty connecting with science at the lab-bench level, raising questions about the value of history of science for science. This essay offers a case study from taxonomy in which lessons learned about particular failings of numerical taxonomy (phenetics) in the second half of the twentieth century bear on the new movement toward DNA barcoding. In particular, it argues that an unwillingness to deal with messy theoretical questions in both cases leads to important problems in the theory and practice of identifying taxa. This argument makes use of scientific and historical considerations in a way that the authors hope leads to convincing conclusions about the history of taxonomy as well as about its present practice.

  10. National History Day: An Ethnohistorical Case Study or Taking the Lid Off the Pot.

    ERIC Educational Resources Information Center

    Page, Marilyn

    This document is a study of the dynamics of National History Day (NHD). The report notices a discrepancy between accounts of National History Day and those concerning contemporary history education. Contemporary history instruction was seen as boring and unimportant, while National History Day activities were seen as a fun opportunity for students…

  11. The Development of Dalton's Atomic Theory as a Case Study in the History of Science: Reflections for Educators in Chemistry

    ERIC Educational Resources Information Center

    Viana, Helio Elael Bonini; Porto, Paulo Alves

    2010-01-01

    The inclusion of the history of science in science curricula--and specially, in the curricula of science teachers--is a trend that has been followed in several countries. The reasons advanced for the study of the history of science are manifold. This paper presents a case study in the history of chemistry, on the early developments of John…

  12. The Development of Dalton's Atomic Theory as a Case Study in the History of Science: Reflections for Educators in Chemistry

    ERIC Educational Resources Information Center

    Viana, Helio Elael Bonini; Porto, Paulo Alves

    2010-01-01

    The inclusion of the history of science in science curricula--and specially, in the curricula of science teachers--is a trend that has been followed in several countries. The reasons advanced for the study of the history of science are manifold. This paper presents a case study in the history of chemistry, on the early developments of John…

  13. A Descriptive Study of the Classroom Instruction Component of the ESEA Title VII Bilingual Education Program. Selected Case Histories.

    ERIC Educational Resources Information Center

    Cardenas, Rene F.; Rudes, Blair A.

    Twenty-two case histories of bilingual education programs funded under Title VII of the Elementary and Secondary Education Act are presented as a companion volume to the technical report of the same study. The case histories were developed from site visits and surveys of administrators, teachers, and parents involved in the program. The program…

  14. Past medical history and pancreatic cancer risk: Results from a multicenter case-control study.

    PubMed

    Maisonneuve, Patrick; Lowenfels, Albert B; Bueno-de-Mesquita, H Bas; Ghadirian, Parviz; Baghurst, Peter A; Zatonski, Witold A; Miller, Anthony B; Duell, Eric J; Boffetta, Paolo; Boyle, Peter

    2010-02-01

    To investigate risk factors that may be linked to pancreatic cancer. We designed a multicenter population-based case-control (823 cases, 1679 control patients) study with data collection by using a common protocol and questionnaire. Participating centers were located in Australia, Canada, the Netherlands, and Poland. After adjustment for confounding factors, a positive history of pancreatitis was associated with pancreatic cancer (odds ratio [OR], 4.68; 95% confidence interval [95% CI], 2.23-9.84). The risk was especially high in heavy smokers (OR, 15.4; 95% CI, 3.18-74.9). Patients with diabetes had an increased risk of developing pancreatic cancer (OR, 2.16; 95% CI, 1.60-2.91). The risk was highest in the first year after the development of diabetes (OR, 6.68; 95% CI, 3.56-12.6) and decreased over time. A history of allergy was associated with a reduced risk of pancreas cancer (OR, 0.64; 95% CI, 0.50-0.82). Patients with newly diagnosed diabetes and patients with pancreatitis, particularly in heavy smokers, have an increased risk for developing pancreatic cancer. In addition to being risk factors, these conditions could be early manifestations of underlying pancreatic cancer. A history of allergy decreases the risk of pancreatic cancer. 2010 Elsevier Inc. All rights reserved.

  15. Ten case history studies of energy efficiency improvements in pulp and paper mills. Final report

    SciTech Connect

    Not Available

    1981-01-01

    The ten technologies chosen for case history development are: sonic sootblowing in boilers, boiler operation on oil-water emulsified fuel, energy efficient motors, computerized control of excess air for boilers, boiler control and load allocation, driving of waste-activated sludge by multiple effect evaporation, pre-drying of hog fuel, lime kiln computerization, heat wheel for process heat recovery, and organic Rankine bottoming cycle for thermomechanical pulping heat recovery. For each case study, there is given: the company name, employee contact, plant summary, a description of the energy consuming process and of the energy-saving action, an assessment of energy savings, and the decision process leading to the adoption of the measure. A data summary for discounted cash flow analysis is tabulated for each case. (LEW)

  16. A Case Study of the In-Class Use of a Video Game for Teaching High School History

    ERIC Educational Resources Information Center

    Watson, William R.; Mong, Christopher J.; Harris, Constance A.

    2011-01-01

    This study examines the case of a sophomore high school history class where "Making History", a video game designed with educational purposes in mind, is used in the classroom to teach about World War II. Data was gathered using observation, focus group and individual interviews, and document analysis. The high school was a rural school…

  17. Family history, comorbidity, smoking and other risk factors in microscopic colitis: a case-control study.

    PubMed

    Wickbom, Anna; Nyhlin, Nils; Montgomery, Scott M; Bohr, Johan; Tysk, Curt

    2017-05-01

    Data on heredity, risk factors and comorbidity in microscopic colitis, encompassing collagenous colitis (CC) and lymphocytic colitis (LC), are limited. The aim was to carry out a case-control study of family history, childhood circumstances, educational level, marital status, smoking and comorbidity in microscopic colitis. A postal questionnaire was sent in 2008-2009 to microscopic colitis patients resident in Sweden and three population-based controls per patient, matched for age, sex and municipality. Some 212 patients and 627 controls participated in the study. There was an association with a family history of microscopic colitis in both CC [odds ratio (OR): 10.3; 95% confidence interval (CI): 2.1-50.4, P=0.004] and LC (OR not estimated, P=0.008). Current smoking was associated with CC [OR: 4.7; 95% CI: 2.4-9.2, P<0.001) and LC (OR: 3.2; 95% CI: 1.6-6.7, P=0.002). The median age at diagnosis was around 10 years earlier in ever-smokers compared with never-smokers.CC was associated with a history of ulcerative colitis (UC) (OR: 8.7, 95% CI: 2.2-33.7, P=0.002), thyroid disease (OR: 2.3; 95% CI: 1.1-4.5, P=0.02), coeliac disease (OR: 13.1; 95% CI: 2.7-62.7, P=0.001), rheumatic disease (OR 1.9; 95% CI: 1.0-3.5, P=0.042) and previous appendicectomy (OR: 2.2; 95% CI: 1.3-3.8, P=0.003), and LC with UC (OR: 6.8; 95% CI: 1.7-28.0, P=0.008), thyroid disease (OR: 2.4; 95% CI: 1.1-5.4, P=0.037) and coeliac disease (OR: 8.7; 95% CI: 2.8-26.7, P<0.001). Association with a family history of microscopic colitis indicates that familial factors may be important. The association with a history of UC should be studied further as it may present new insights into the pathogenesis of microscopic colitis and UC.

  18. Case histories in forensic medicine.

    PubMed

    Madea, Burkhard

    2007-01-17

    Case histories make up a great part of publications in forensic medicine, especially forensic pathology, although considered low on the hierarchy of evidence based medicine because of its inherent anecdotal nature. Meanwhile some journals exclude case histories categorically from publication. The boom of case histories in forensic medicine has not only opportunity reasons (easily [even mental] and cheap to do) but also structural reasons: due to its tasks in case work many items of forensic medicine can not be simulated experimentally for ethical reasons (violent death, traumatic injuries, sexual assault, poisonings, influence of alcohol and drugs on driving ability and legal responsibility, medical malpractice, adverse events during medical care). In these fields the role of case histories is mainly the augmentation of experience based knowledge. However, quality aspects have to be considered and case histories should be the basis for systematic or hypothesis based research.

  19. The Development of Dalton's Atomic Theory as a Case Study in the History of Science: Reflections for Educators in Chemistry

    NASA Astrophysics Data System (ADS)

    Viana, Hélio Elael Bonini; Porto, Paulo Alves

    2010-01-01

    The inclusion of the history of science in science curricula—and specially, in the curricula of science teachers—is a trend that has been followed in several countries. The reasons advanced for the study of the history of science are manifold. This paper presents a case study in the history of chemistry, on the early developments of John Dalton’s atomic theory. Based on the case study, several questions that are worth discussing in educational contexts are pointed out. It is argued that the kind of history of science that was made in the first decades of the twentieth century (encyclopaedic, continuist, essentially anachronistic) is not appropriate for the development of the competences that are expected from the students of sciences in the present. Science teaching for current days will benefit from the approach that may be termed the “new historiography of science”.

  20. Industrial Case Histories

    DTIC Science & Technology

    2001-04-05

    for each analysis will helpfully dispel this theory. Key Words: Imbalance; Blade Pass; Whirl; Whip; Structural Resonance ; Variable Frequency Drives...Tower Blade Pass Resonance Problem: This unit had a history of running high vibration amplitudes in the 20 Hz frequency range. The operating speed of...and created their own problem. If the time had been spent performing resonance checks before making the change, this problem would have been

  1. Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.

    PubMed

    Bigdeli, Tim B; Ripke, Stephan; Bacanu, Silviu-Alin; Lee, Sang Hong; Wray, Naomi R; Gejman, Pablo V; Rietschel, Marcella; Cichon, Sven; St Clair, David; Corvin, Aiden; Kirov, George; McQuillin, Andrew; Gurling, Hugh; Rujescu, Dan; Andreassen, Ole A; Werge, Thomas; Blackwood, Douglas H R; Pato, Carlos N; Pato, Michele T; Malhotra, Anil K; O'Donovan, Michael C; Kendler, Kenneth S; Fanous, Ayman H

    2016-03-01

    Genome-wide association studies (GWAS) of schizophrenia have yielded more than 100 common susceptibility variants, and strongly support a substantial polygenic contribution of a large number of small allelic effects. It has been hypothesized that familial schizophrenia is largely a consequence of inherited rather than environmental factors. We investigated the extent to which familiality of schizophrenia is associated with enrichment for common risk variants detectable in a large GWAS. We analyzed single nucleotide polymorphism (SNP) data for cases reporting a family history of psychotic illness (N = 978), cases reporting no such family history (N = 4,503), and unscreened controls (N = 8,285) from the Psychiatric Genomics Consortium (PGC1) study of schizophrenia. We used a multinomial logistic regression approach with model-fitting to detect allelic effects specific to either family history subgroup. We also considered a polygenic model, in which we tested whether family history positive subjects carried more schizophrenia risk alleles than family history negative subjects, on average. Several individual SNPs attained suggestive but not genome-wide significant association with either family history subgroup. Comparison of genome-wide polygenic risk scores based on GWAS summary statistics indicated a significant enrichment for SNP effects among family history positive compared to family history negative cases (Nagelkerke's R(2 ) = 0.0021; P = 0.00331; P-value threshold <0.4). Estimates of variability in disease liability attributable to the aggregate effect of genome-wide SNPs were significantly greater for family history positive compared to family history negative cases (0.32 and 0.22, respectively; P = 0.031). We found suggestive evidence of allelic effects detectable in large GWAS of schizophrenia that might be specific to particular family history subgroups. However, consideration of a polygenic risk score indicated a significant

  2. A case control study on family history as a risk factor for herpes zoster and associated outcomes, Beijing, China.

    PubMed

    Suo, Luodan; Lu, Li; Li, Juan; Sun, Mu; Wang, Haihong; Peng, Xinhui; Yang, Fan; Pang, Xinghuo; Marin, Mona; Wang, Chengbin

    2017-05-09

    Hospital-based case control studies have found family history of herpes zoster (HZ) was associated with risk of HZ, but the role of family history is not fully examined for other HZ-associated outcomes such as recurrent HZ, occurrence of postherpetic neuralgia (PHN), and HZ with different pain severities. We conducted a population-based matched case control study. HZ cases that occurred during December 1, 2011 to November 30, 2012 were identified by face-to-face interview with all residents of eight selected communities/villages from three districts of Beijing, China. Medical records were reviewed for those who sought healthcare for HZ. For each case-patient, three, age-matched controls (±5 years) without HZ were enrolled from the same community/village of the matched case. Data on family history of HZ were collected by interview and only defined among first-degree relatives. A total of 227 case-patients and 678 matched controls were enrolled. Case-patients were more likely to report a family history of HZ [odds ratio (OR) =2.4, P = 0.002]. Compared with controls, association of family history decreased from HZ with PHN to HZ without PHN (OR = 6.0 and 2.3, respectively; P = 0.002 for trend), from recurrent HZ to primary HZ (OR = 9.4 and 2.2, respectively; P = 0.005 for trend), and from HZ with moderate or severe pain to HZ with mild or no pain (OR = 3.2 and 0.8, respectively; P < 0.001 for trend). Family history of HZ was associated with HZ occurrence and was more likely in HZ case-patients with PHN, recurrences, and painful HZ.

  3. Family history of cancer and the risk of bladder cancer: A case-control study from Italy.

    PubMed

    Turati, Federica; Bosetti, Cristina; Polesel, Jerry; Serraino, Diego; Montella, Maurizio; Libra, Massimo; Facchini, Gaetano; Ferraroni, Monica; Tavani, Alessandra; La Vecchia, Carlo; Negri, Eva

    2017-06-01

    A family history of bladder cancer has been associated with the risk of bladder cancer, but quantification of the excess risk in different populations is still a relevant issue. Further, the role of a family history of other cancers on the risk of bladder cancer remains unclear. We analyzed data from an Italian case-control study, including 690 bladder cancer cases and 665 hospital controls. Odds ratios (ORs) were estimated through unconditional logistic regression models, adjusted for sex, age, study center, year of interview and further for education, smoking and sibling's number. The OR for family history of bladder cancer was 2.13 (95% confidence intervals (95%CIs) 1.02-4.49) from the model with partial adjustment, and 1.99 (95%CI 0.91-4.32) after additional adjustment for smoking and siblings' number, based on 23 cases (3.3%) and 11 controls (1.7%) with a family history of bladder cancer. The fully adjusted OR was 3.77 when the relative was diagnosed at age below 65years. Smokers with a family history of bladder cancer had a four-fold increased risk compared to non-smokers without a family history. Bladder cancer risk was significantly increased among subjects with a family history of hemolymphopoietic cancers (OR=2.97, 95%CI 1.35-6.55). Family history of cancer at other sites showed no significant association with bladder cancer risk. This study confirms an approximately two-fold increased risk of bladder cancer for family history of bladder cancer, and indicates a possible familial clustering of bladder cancer with cancers of the hemolymphopoietic system. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. History of cholelithiasis and cancer risk in a network of case-control studies.

    PubMed

    Tavani, A; Rosato, V; Di Palma, F; Bosetti, C; Talamini, R; Dal Maso, L; Zucchetto, A; Levi, F; Montella, M; Negri, E; Franceschi, S; La Vecchia, C

    2012-08-01

    We analyzed the relationship between cholelithiasis and cancer risk in a network of case-control studies conducted in Italy and Switzerland in 1982-2009. The analyses included 1997 oropharyngeal, 917 esophageal, 999 gastric, 23 small intestinal, 3726 colorectal, 684 liver, 688 pancreatic, 1240 laryngeal, 6447 breast, 1458 endometrial, 2002 ovarian, 1582 prostate, 1125 renal cell, 741 bladder cancers, and 21 284 controls. The odds ratios (ORs) were estimated by multiple logistic regression models. The ORs for subjects with history of cholelithiasis compared with those without were significantly elevated for small intestinal (OR=3.96), prostate (OR=1.36), and kidney cancers (OR=1.57). These positive associations were observed ≥10 years after diagnosis of cholelithiasis and were consistent across strata of age, sex, and body mass index. No relation was found with the other selected cancers. A meta-analysis including this and three other studies on the relation of cholelithiasis with small intestinal cancer gave a pooled relative risk of 2.35 [95% confidence interval (CI) 1.82-3.03]. In subjects with cholelithiasis, we showed an appreciably increased risk of small intestinal cancer and suggested a moderate increased risk of prostate and kidney cancers. We found no material association with the other cancers considered.

  5. Case history studies of energy conservation improvements in the dairy industry

    SciTech Connect

    Not Available

    1982-06-01

    Presented are ten case histories about energy-efficient technologies implemented by the dairy industry. For each case is presented: the name and location of the company, and its product line; energy consumption and costs at the plant before and after implementation of energy-conserving technology; the factors that prompted the investment; and product quality as a result of the new equipment. The measures presented are: refrigeration compressor replacement, turbulators in boiler tubes, stack exchange on boilers, reverse osmosis, six-effect evaporator, multi-effect evaporator with thermal vapor recompressor, spray dryer heat recovery, efficient compressor operations, mechanical vapor recompression evaporator, preheated spray dryer air with recoverable waste heat. (LEW)

  6. Plagiarism: A case history.

    PubMed

    Sadler, L L

    1977-03-01

    A case of plagiarism involving duplication of the author's drawings is discussed. The chronology of events leading to an out-of-court settlement is reviewed and an attempt is made to clarify certain often misunderstood points in the Copyright Law as it applies to illustrators.

  7. Cross-Border Collaboration in History among Nordic Students: A Case Study about Creating Innovative ICT Didactic Models

    ERIC Educational Resources Information Center

    Spante, Maria; Karlsen, Asgjerd Vea; Nortvig, Anne-Mette; Christiansen, Rene B.

    2014-01-01

    Gränsöverskridande Nordisk Undervisning/Utdanelse (GNU, meaning Cross-Border Nordic Education), the larger Nordic project, under which this case study was carried out, aims at developing innovative, cross-border teaching models in different subject domains in elementary school, including mathematics, language, science, social studies and history.…

  8. Aerodynamic instability: A case history

    NASA Technical Reports Server (NTRS)

    Eisenmann, R. C.

    1985-01-01

    The identification, diagnosis, and final correction of complex machinery malfunctions typically require the correlation of many parameters such as mechanical construction, process influence, maintenance history, and vibration response characteristics. The progression is reviewed of field testing, diagnosis, and final correction of a specific machinery instability problem. The case history presented addresses a unique low frequency instability problem on a high pressure barrel compressor. The malfunction was eventually diagnosed as a fluidic mechanism that manifested as an aerodynamic disturbance to the rotor assembly.

  9. Family history of cancer and the risk of laryngeal cancer: a case-control study from Italy and Switzerland.

    PubMed

    Garavello, Werner; Turati, Federica; Bosetti, Cristina; Talamini, Renato; Levi, Fabio; Lucenteforte, Ersilia; Chiesa, Fausto; Franceschi, Silvia; La Vecchia, Carlo; Negri, Eva

    2012-02-01

    Only limited data is available on the relationship between family history of laryngeal and other neoplasms and laryngeal cancer risk. We investigated the issue using data from a multicentre case-control study conducted in Italy and Switzerland between 1992 and 2009 including 852 cases with histologically confirmed laryngeal cancer and 1970 controls admitted to hospital for acute, non neoplastic conditions. Unconditional logistic regression models adjusted for age, sex, study center, education, tobacco smoking, alcohol drinking and number of siblings were used to estimate the odds ratios (ORs) of laryngeal cancer. The multivariate OR was 2.8 (95% confidence interval [CI], 1.5-5.3) in subjects reporting a first-degree relative with laryngeal cancer, as compared to subjects with no family history. The OR was higher when the relative was diagnosed before 60 years of age (OR = 3.5, 95% CI 1.4-8.8). As compared to subjects without family history, non-smokers, and moderate drinkers, the OR was 37.1 (95% CI 9.9-139.4) for current smokers, heavy drinkers, with family history of laryngeal cancer. Family history of colorectal (OR = 1.5, 95% CI 1.0-2.3) and kidney (OR = 3.8, 95% CI 1.2-12.1) cancer were also associated to an increased risk of laryngeal cancer, while no significant increase in risk was found for family history of cancer at all sites, excluding the larynx (OR = 1.1).

  10. A Case Study of Co-Teaching in an Inclusive Secondary High-Stakes World History I Classroom

    ERIC Educational Resources Information Center

    van Hover, Stephanie; Hicks, David; Sayeski, Kristin

    2012-01-01

    In order to provide increasing support for students with disabilities in inclusive classrooms in high-stakes testing contexts, some schools have implemented co-teaching models. This qualitative case study explores how 1 special education teacher (Anna) and 1 general education history teacher (John) make sense of working together in an inclusive…

  11. The Momotombo Geothermal Field, Nicaragua: Exploration and development case history study

    SciTech Connect

    1982-07-01

    This case history discusses the exploration methods used at the Momotombo Geothermal Field in western Nicaragua, and evaluates their contributions to the development of the geothermal field models. Subsequent reservoir engineering has not been synthesized or evaluated. A geothermal exploration program was started in Nicaragua in 1966 to discover and delineate potential geothermal reservoirs in western Nicaragua. Exploration began at the Momotombo field in 1970 using geological, geochemical, and geophysical methods. A regional study of thermal manifestations was undertaken and the area on the southern flank of Volcan Momotombo was chosen for more detailed investigation. Subsequent exploration by various consultants produced a number of geotechnical reports on the geology, geophysics, and geochemistry of the field as well as describing production well drilling. Geological investigations at Momotombo included photogeology, field mapping, binocular microscope examination of cuttings, and drillhole correlations. Among the geophysical techniques used to investigate the field sub-structure were: Schlumberger and electromagnetic soundings, dipole mapping and audio-magnetotelluric surveys, gravity and magnetic measurements, frequency domain soundings, self-potential surveys, and subsurface temperature determinations. The geochemical program analyzed the thermal fluids of the surface and in the wells. This report presents the description and results of exploration methods used during the investigative stages of the Momotombo Geothermal Field. A conceptual model of the geothermal field was drawn from the information available at each exploration phase. The exploration methods have been evaluated with respect to their contributions to the understanding of the field and their utilization in planning further development. Our principal finding is that data developed at each stage were not sufficiently integrated to guide further work at the field, causing inefficient use of

  12. Case history studies of energy conservation improvements in the meat industry

    SciTech Connect

    Not Available

    1982-06-01

    Presented are case histories for ten energy-efficient technologies implemented by the meat industry. For each case is presented: the name and location of the plant, name of plant employee contact with address and telephone number, energy consumption and costs at the plant before and after implementation of energy-conserving technology, description of the investment decision process, and changes in production or product quality as a result of the new equipment. The measures presented are: continuous rendering, high-pressure return on the boiler, heat recovery from condensate return and flash steam, continuous whole blood processing, preheating of process water with recovered refrigeration waste heat, continuous rendering of poultry scraps, electrical stimulation of beef, preheating and storing process water with recovered refrigeration waste heat, microcomputer control system, and housekeeping improvements. (LEW)

  13. Familial history of cancer and childhood acute leukemia: a French population-based case-control study

    PubMed Central

    Ripert, Mahaut; Menegaux, Florence; Perel, Yves; Méchinaud, Françoise; Plouvier, Emmanuel; Gandemer, Virginie; Lutz, Patrick; Vannier, Jean-Pierre; Lamagnére, Jean-Pierre; Margueritte, Geneviève; Boutard, Patrick; Robert, Alain; Armari-Alla, Corinne; Munzer, Martine; Millot, Frédéric; de Lumley, Lionel; Berthou, Christian; Rialland, Xavier; Pautard, Brigitte; Clavel, Jacqueline

    2007-01-01

    Objective A case-control study was conducted to investigate the role of a familial history of cancer in the etiology of childhood acute leukemia (AL). Methods The history of cancer in the relatives of 472 cases was compared to that of 567 population-based controls. Recruitment was frequency matched on age, gender and region. The familial history of cancer in each child’s relatives was reported by the mother in response to a standardized self-administered questionnaire. Results A familial history of solid tumor in first- or second-degree relatives was associated with an increased risk of ALL (OR=1.6 [1.2–2.1]), while a familial history of hematopoietic malignancies in first- or second-degree relatives was associated with an increased risk of AML (OR=4.3 [1.4–13]). The ORs for the histories of cancer increased with the number of relatives with cancer (OR=1.5 [1.1–2.0] for one relative and OR=2.3 [1.3–3.8] for two relatives or more; ptrend<0.0001). Significant associations between childhood AL and familial history of genital cancers and brain tumor were also observed (OR=2.7 [1.2–5.8], OR=10.7 [1.3–86], respectively). Conclusion This study supports the hypothesis that a familial history of cancer may play a role in the etiology of childhood acute leukemia. It also evidences some specific associations that require further investigation. PMID:17923819

  14. A Bayesian Semiparametric Approach for Incorporating Longitudinal Information on Exposure History for Inference in Case-Control Studies

    PubMed Central

    Bhadra, Dhiman; Daniels, Michael J.; Kim, Sungduk; Ghosh, Malay; Mukherjee, Bhramar

    2014-01-01

    In a typical case-control study, exposure information is collected at a single time-point for the cases and controls. However, case-control studies are often embedded in existing cohort studies containing a wealth of longitudinal exposure history on the participants. Recent medical studies have indicated that incorporating past exposure history, or a constructed summary measure of cumulative exposure derived from the past exposure history, when available, may lead to more precise and clinically meaningful estimates of the disease risk. In this paper, we propose a flexible Bayesian semiparametric approach to model the longitudinal exposure profiles of the cases and controls and then use measures of cumulative exposure based on a weighted integral of this trajectory in the final disease risk model. The estimation is done via a joint likelihood. In the construction of the cumulative exposure summary, we introduce an influence function, a smooth function of time to characterize the association pattern of the exposure profile on the disease status with different time windows potentially having differential influence/weights. This enables us to analyze how the present disease status of a subject is influenced by his/her past exposure history conditional on the current ones. The joint likelihood formulation allows us to properly account for uncertainties associated with both stages of the estimation process in an integrated manner. Analysis is carried out in a hierarchical Bayesian framework using Reversible jump Markov chain Monte Carlo (RJMCMC) algorithms. The proposed methodology is motivated by, and applied to a case-control study of prostate cancer where longitudinal biomarker information is available for the cases and controls. PMID:22313248

  15. Monolith Joint Repairs: Case Histories

    DTIC Science & Technology

    1989-08-01

    REPAIR, EVALUATION, MAINTENANCE, AND REHABILITATION RESEARCH PROGRAM TECHNICAL REPORT REMR-CS-22 MONOLITH JOINT REPAIRS: CASE HISTORVS.Z by James G ...Washington, DC 20314-1000 32307 S11. TITLE (Include Security Classification) Monolith Joint Repairs: Case Histories 12. PERSONAL AUTHOR(S) May. James G ...Research Work Unit 32307, "Tech- niques for Joint Repair and Rehabilitation," for which MAJ James G . May, CE, is the Principal Investigator. This work unit

  16. Teaching Nineteenth Century Afro-American History: The Case Study Approach.

    ERIC Educational Resources Information Center

    Cotton, Barbara R.

    1979-01-01

    In this case study approach, teaching episodes designed using Richard Wade's thesis concerning slavery in the city are presented. Episodes include studies of Jacksonville, Florida, Savannah, Georgia, and New Orleans, Louisiana. (Author/RLV)

  17. Teaching Nineteenth Century Afro-American History: The Case Study Approach.

    ERIC Educational Resources Information Center

    Cotton, Barbara R.

    1979-01-01

    In this case study approach, teaching episodes designed using Richard Wade's thesis concerning slavery in the city are presented. Episodes include studies of Jacksonville, Florida, Savannah, Georgia, and New Orleans, Louisiana. (Author/RLV)

  18. Lifestyle, family history, and risk of idiopathic Parkinson disease: a large Danish case-control study.

    PubMed

    Kenborg, Line; Lassen, Christina F; Ritz, Beate; Andersen, Klaus K; Christensen, Jane; Schernhammer, Eva S; Hansen, Johnni; Wermuth, Lene; Rod, Naja H; Olsen, Jørgen H

    2015-05-15

    The relationship between Parkinson disease (PD) and smoking has been examined in several studies, but little is known about smoking in conjunction with other behaviors and a family history of PD. Using unconditional logistic regression analysis, we studied individual and joint associations of these factors with idiopathic PD among 1,808 Danish patients who were diagnosed in 1996-2009 and matched to 1,876 randomly selected population controls. Although there was a downward trend in duration of smoking, this was not observed for daily tobacco consumption. A moderate intake of caffeine (3.1-5 cups/day) was associated with a lower odds ratio for PD (0.45, 95% confidence interval: 0.34, 0.62), as was a moderate intake of alcohol (3.1-7 units/week) (odds ratio = 0.60, 95% confidence interval: 0.58, 0.84); a higher daily intake did not reduce the odds further. When these behaviors were studied in combination with smoking, the odds ratios were lower than those for each one alone. Compared with never smokers with no family history of PD, never smokers who did have a family history had an odds ratio of 2.81 (95% confidence interval: 1.91, 4.13); for smokers with a family history, the odds ratio was 1.60 (95% confidence interval: 1.15, 2.23). In conclusion, duration of smoking seems to be more important than intensity in the relationship between smoking and idiopathic PD. The finding of lower risk estimates for smoking in combination with caffeine or alcohol requires further confirmation.

  19. Lifestyle, Family History, and Risk of Idiopathic Parkinson Disease: A Large Danish Case-Control Study

    PubMed Central

    Kenborg, Line; Lassen, Christina F.; Ritz, Beate; Andersen, Klaus K.; Christensen, Jane; Schernhammer, Eva S.; Hansen, Johnni; Wermuth, Lene; Rod, Naja H.; Olsen, Jørgen H.

    2015-01-01

    The relationship between Parkinson disease (PD) and smoking has been examined in several studies, but little is known about smoking in conjunction with other behaviors and a family history of PD. Using unconditional logistic regression analysis, we studied individual and joint associations of these factors with idiopathic PD among 1,808 Danish patients who were diagnosed in 1996–2009 and matched to 1,876 randomly selected population controls. Although there was a downward trend in duration of smoking, this was not observed for daily tobacco consumption. A moderate intake of caffeine (3.1–5 cups/day) was associated with a lower odds ratio for PD (0.45, 95% confidence interval: 0.34, 0.62), as was a moderate intake of alcohol (3.1–7 units/week) (odds ratio = 0.60, 95% confidence interval: 0.58, 0.84); a higher daily intake did not reduce the odds further. When these behaviors were studied in combination with smoking, the odds ratios were lower than those for each one alone. Compared with never smokers with no family history of PD, never smokers who did have a family history had an odds ratio of 2.81 (95% confidence interval: 1.91, 4.13); for smokers with a family history, the odds ratio was 1.60 (95% confidence interval: 1.15, 2.23). In conclusion, duration of smoking seems to be more important than intensity in the relationship between smoking and idiopathic PD. The finding of lower risk estimates for smoking in combination with caffeine or alcohol requires further confirmation. PMID:25925389

  20. Studying Ancient History.

    ERIC Educational Resources Information Center

    Barrow, Robin

    1982-01-01

    Defends the value and relevance of the study of ancient history and classics in history curricula. The unique homogeneity of the classical period contributes to its instructional manageability. A year-long, secondary-level course on fifth-century Greece and Rome is described to illustrate effective approaches to teaching ancient history. (AM)

  1. Studying Ancient History.

    ERIC Educational Resources Information Center

    Barrow, Robin

    1982-01-01

    Defends the value and relevance of the study of ancient history and classics in history curricula. The unique homogeneity of the classical period contributes to its instructional manageability. A year-long, secondary-level course on fifth-century Greece and Rome is described to illustrate effective approaches to teaching ancient history. (AM)

  2. The Effect of Positive Family History of Autoimmunity in Juvenile Idiopathic Arthritis Characteristics; a Case Control Study

    PubMed Central

    Khani, Mehdi; Ziaee, Vahid; Moradinejad, Mohamad-Hassan; Parvaneh, Nima

    2013-01-01

    Objective To compare Juvenile Idiopathic Arthritis (JIA) patients with and without family history of autoimmune disease with respect to clinical features and laboratory data. Methods Sixteen JIA patients with family history of autoimmune disease were identified during study, 32 patients were chosen for comparative group from referred patients to the rheumatology clinic according to the date of referral. Two groups were compared with respect to age of onset, sex, subtype, disease activity, duration of active disease and laboratory variables. Findings The age of onset was significantly lower in JIA patients with family history of autoimmunity (4.7 years vs. 7.0 years; P=0.02), polyarthicular subtype was more frequent in patients with positive family history (50% vs.25%; P=0.04) most of JIA patients with positive family history were in the active phase at the time of study (64% vs 25%; P=0.02) and had a longer duration of active disease (21.0 months vs 12.3 months; P=0.04). Patients with positive family history had more positive ANA (43.5%% vs 12.5%; P=0.01) and also more positive ADA (75% vs 20.8%; P=0.002). Two groups were similar according to sex, and other laboratory variables. Conclusion JIA patients with family history of autoimmune disease seem to have a more severe disease than patients without such family history, they are younger at the onset, and have mostly poyarthicular subtype. They also have more ANA and ADA positivity. These findings are different from familial JIA case-control studies according to active disease duration, subtype, and ANA positivity. PMID:24800019

  3. Case studies of children presenting with a history of ritualistic abuse.

    PubMed

    King, G F; Yorker, B

    1996-01-01

    Ritualistic child abuse is an alarming and controversial problem. Child psychiatric nurses need to increase their awareness of the clinical picture associated with this specific form of abuse. This article reviews the literature to date on ritualistic child abuse and addresses the controversy surrounding the phenomena. A small research project using historical data collection methods reviewed hospital records of children with a documented history of ritualistic abuse. Results are organized into clusters of linked interrelated characteristics. The symptom characteristics of these children revealed medical/somatic symptoms, distortion of self-oncept and world view, and a variety of emotional disturbances. The findings of this study are presented with implications for nurses who care for clients with a history of ritualistic abuse.

  4. Teaching Recent History in Countries that Have Experienced Human Rights Violations: Case Studies from Chile

    ERIC Educational Resources Information Center

    Toledo, Maria Isabel; Magendzo, Abraham; Gazmuri, Renato

    2011-01-01

    Incorporating recent history into the educational curricula of countries that have experienced human rights violations combines the complexities of teaching history, teaching recent history, and human rights education. Recent history makes a historical analysis of social reality and a historiographical analysis of the immediate. It is located…

  5. Teaching Recent History in Countries that Have Experienced Human Rights Violations: Case Studies from Chile

    ERIC Educational Resources Information Center

    Toledo, Maria Isabel; Magendzo, Abraham; Gazmuri, Renato

    2011-01-01

    Incorporating recent history into the educational curricula of countries that have experienced human rights violations combines the complexities of teaching history, teaching recent history, and human rights education. Recent history makes a historical analysis of social reality and a historiographical analysis of the immediate. It is located…

  6. [Somatoform disorders in neurology visits: history and circumstances: retrospective study of 124 cases].

    PubMed

    Dubas, F; Thomas-Antérion, C

    2012-12-01

    We report 124 cases of somatoform disorders, considering psychogenic disorders at the same level as neurological disorders. We noted any psychic, somatic or social condition (history taking) and facilitating circumstances. The patients were aged 16 to 84 years old; 71.7% were women. We observed pain (35.4%), psychogenic headache (25%), sensorimotor loss (27.4%), gait and psychogenic tremor (17.7%), cognitive disorders (11.8%), ocular symptoms (7.2%), and urogenital symptoms (2.4%). Delay to consultation ranged from a few days to 20 years. Psychiatric comorbidity was noted in 30.6% of the cases. In 55.6% of 124 cases, we observed a psychological background. It was a childhood trauma in 15.3% of these cases. In one-third of the 124 situations, we noted an underlying somatic or social condition. Facilitation conditions were frequently mixed. Somatic and/or psychological conditions were noted in one-third of the 124 cases and social conditions in half of them. The neurologist is faced with the challenge of naming the symptom (most often labelled a functional disorder) and of making the decision to stop or limit investigations. Visits by patients with psychogenic disorders make up a significant percentage of neurology speciality appointments. The neurologist should not limit the consultation to differentiating "real" symptoms from psychogenic somatoform disorders, but should also propose a straightforward compassionate approach for effective therapeutic care. By carefully listening to the patient's dialogue, the neurologist can help the patient give meaning to the symptoms, and progress towards improved well-being.

  7. A multicentre case control study on complicated coeliac disease: two different patterns of natural history, two different prognoses

    PubMed Central

    2014-01-01

    Background Coeliac disease is a common enteropathy characterized by an increased mortality mainly due to its complications. The natural history of complicated coeliac disease is characterised by two different types of course: patients with a new diagnosis of coeliac disease that do not improve despite a strict gluten-free diet (type A cases) and previously diagnosed coeliac patients that initially improved on a gluten-free diet but then relapsed despite a strict diet (type B cases). Our aim was to study the prognosis and survival of A and B cases. Methods Clinical and laboratory data from coeliac patients who later developed complications (A and B cases) and sex- and age-matched coeliac patients who normally responded to a gluten-free diet (controls) were collected among 11 Italian centres. Results 87 cases and 136 controls were enrolled. Complications tended to occur rapidly after the diagnosis of coeliac disease and cumulative survival dropped in the first months after diagnosis of complicated coeliac disease. Thirty-seven cases died (30/59 in group A, 7/28 in group B). Type B cases presented an increased survival rate compared to A cases. Conclusions Complicated coeliac disease is an extremely serious condition with a high mortality and a short survival. Survival depends on the type of natural history. PMID:25103857

  8. A multicentre case control study on complicated coeliac disease: two different patterns of natural history, two different prognoses.

    PubMed

    Biagi, Federico; Marchese, Alessandra; Ferretti, Francesca; Ciccocioppo, Rachele; Schiepatti, Annalisa; Volta, Umberto; Caio, Giacomo; Ciacci, Carolina; Zingone, Fabiana; D'Odorico, Anna; Carroccio, Antonio; Ambrosiano, Giuseppe; Mansueto, Pasquale; Gasbarrini, Antonio; Piscaglia, Anna Chiara; Andrealli, Alida; Astegiano, Marco; Segato, Sergio; Neri, Matteo; Meggio, Alberto; de Pretis, Giovanni; De Vitis, Italo; Gobbi, Paolo; Corazza, Gino Roberto

    2014-08-07

    Coeliac disease is a common enteropathy characterized by an increased mortality mainly due to its complications. The natural history of complicated coeliac disease is characterised by two different types of course: patients with a new diagnosis of coeliac disease that do not improve despite a strict gluten-free diet (type A cases) and previously diagnosed coeliac patients that initially improved on a gluten-free diet but then relapsed despite a strict diet (type B cases). Our aim was to study the prognosis and survival of A and B cases. Clinical and laboratory data from coeliac patients who later developed complications (A and B cases) and sex- and age-matched coeliac patients who normally responded to a gluten-free diet (controls) were collected among 11 Italian centres. 87 cases and 136 controls were enrolled. Complications tended to occur rapidly after the diagnosis of coeliac disease and cumulative survival dropped in the first months after diagnosis of complicated coeliac disease. Thirty-seven cases died (30/59 in group A, 7/28 in group B). Type B cases presented an increased survival rate compared to A cases. Complicated coeliac disease is an extremely serious condition with a high mortality and a short survival. Survival depends on the type of natural history.

  9. Space-time analysis of testicular cancer clusters using residential histories: a case-control study in Denmark.

    PubMed

    Sloan, Chantel D; Nordsborg, Rikke B; Jacquez, Geoffrey M; Raaschou-Nielsen, Ole; Meliker, Jaymie R

    2015-01-01

    Though the etiology is largely unknown, testicular cancer incidence has seen recent significant increases in northern Europe and throughout many Western regions. The most common cancer in males under age 40, age period cohort models have posited exposures in the in utero environment or in early childhood as possible causes of increased risk of testicular cancer. Some of these factors may be tied to geography through being associated with behavioral, cultural, sociodemographic or built environment characteristics. If so, this could result in detectable geographic clusters of cases that could lead to hypotheses regarding environmental targets for intervention. Given a latency period between exposure to an environmental carcinogen and testicular cancer diagnosis, mobility histories are beneficial for spatial cluster analyses. Nearest-neighbor based Q-statistics allow for the incorporation of changes in residency in spatial disease cluster detection. Using these methods, a space-time cluster analysis was conducted on a population-wide case-control population selected from the Danish Cancer Registry with mobility histories since 1971 extracted from the Danish Civil Registration System. Cases (N=3297) were diagnosed between 1991 and 2003, and two sets of controls (N=3297 for each set) matched on sex and date of birth were included in the study. We also examined spatial patterns in maternal residential history for those cases and controls born in 1971 or later (N= 589 case-control pairs). Several small clusters were detected when aligning individuals by year prior to diagnosis, age at diagnosis and calendar year of diagnosis. However, the largest of these clusters contained only 2 statistically significant individuals at their center, and were not replicated in SaTScan spatial-only analyses which are less susceptible to multiple testing bias. We found little evidence of local clusters in residential histories of testicular cancer cases in this Danish population.

  10. Art, evolution, and history: a case study of paradigm change in anthropology.

    PubMed

    Thoresen, T H

    1977-04-01

    An ethnological controversy over the origin and evolution of decorative art is documented for the period 1896-1904 and is used to test the relevance in anthropology of Thomas Kuhn's outline of the structure of scientific revolutions. Using a combination of archival materials and content analysis of professional periodicals, both the appropriateness and the limitations of Kuhn's scheme are explored. The conclusion is that paradigms and scientific revolutions are valid and useful concepts for use in the history of anthropology, but that for the particular period under study they are insufficient. Nonparadigmatic aspects of anthropology's supporting communities must also be considered, especially anthropology's "permeable boundaries".

  11. Craniotomy: the first case histories.

    PubMed

    Martin

    1999-07-01

    The oldest existing case histories of craniotomy are from the false Hippocratic writings, about 330 BC, and one is reconstructed about the death of Ptolemy VI in 145 BC. Greek surgeons had rational indications for trepanning, when the difficulties of the times are understood. All compound fractures were infected, so death from an extradural abscess was likely. Trepanning was intended to drain the extra dural space. Copyright 1999 Harcourt Publishers Ltd.

  12. A case-control study of the association between socio-demographic, lifestyle and medical history factors and multiple sclerosis.

    PubMed

    Ghadirian, P; Dadgostar, B; Azani, R; Maisonneuve, P

    2001-01-01

    The etiology of multiple sclerosis (MS) remains poorly understood. Socio-demographic characteristics may play important roles in its development. In a case-control study of MS, a total of 200 newly diagnosed MS patients and 202 frequency age- and sex-matched controls were studied. A direct and significant association was observed between cigarette smoking and the risk of MS. Higher education seemed to reduce the risk of MS. Contact with cats was inversely associated with MS, particularly in males, whereas contact with caged birds increased the risk significantly, especially in females. A strong family aggregation of MS was observed among cases. A past history of trauma and eye problems appeared to pose a high risk of MS. Cases had a significant family history of eye problems, mumps, measles, rubella, cancer and auto-immune diseases. If smoking and history of certain infectious diseases increase the risk of MS significantly, they could be modified and avoided, thereby reducing the likelihood of being afflicted by MS.

  13. Risk of physical assault against school educators with histories of occupational and other violence: a case-control study.

    PubMed

    Nachreiner, Nancy M; Gerberich, Susan G; Ryan, Andrew D; Erkal, Sibel; McGovern, Patricia M; Church, Timothy R; Mongin, Steven J; Feda, Denise M

    2012-01-01

    A case-control study design was used to investigate risks of work-related physical assault (PA) associated with a history of violent victimization among educators. A total of 6,469 state-licensed educators (Kindergarten - Grade 12) worked in the previous 12~months and were eligible to participate. Exposure data were collected from cases (reporting a PA event in previous 12 months, n=290) for the month before PA, and from controls (no work-related PA in previous 12 months; n=867) for a randomly selected working month. Odds ratios and 95% confidence intervals identified increased risks for educators with any prior history of work-related (17.3, 11.4-26.3) or non-work-related PA (2.0, 1.2-3.5). In addition, PA risk in the previous twelve months increased with the number of previous victimizations, and risk also increased for educators with histories of non-physical violence (work- and non work-related). The results present a compelling case for targeted interventions and further research.

  14. Writing history: case study of the university of Victoria School of Nursing.

    PubMed

    Scaia, Margaret R; Young, Lynne

    2013-04-23

    A historical examination of a nursing curriculum is a bridge between past and present from which insights to guide curriculum development can be gleaned. In this paper, we use the case study method to examine how the University of Victoria School of Nursing (UVic SON), which was heavily influenced by the ideology of second wave feminism, contributed to a change in the direction of nursing education from task-orientation to a content and process orientation. This case study, informed by a feminist lens, enabled us to critically examine the introduction of a "revolutionary" caring curriculum at the UVic SON. Our research demonstrates the fault lines and current debates within which a feminist informed curriculum continues to struggle for legitimacy and cohesion. More work is needed to illuminate the historical basis of these debates and to understand more fully the complex landscape that has constructed the social and historical position of women and nursing in Canadian society today.

  15. Pathological study of the prevalence of silicosis among coal miners in Iran: A case history

    NASA Astrophysics Data System (ADS)

    Zare Naghadehi, Masoud; Sereshki, Farhang; Mohammadi, F.

    2014-02-01

    One of the most hazardous diseases that is commonly associated with the coal mining industry is Silicosis which caused by dust inhalation. This disease occurs as a result of prolonged breathing of dust containing silica (quartz). The generation of coal mine dust during underground and surface coal mining is the most significant source of coal dust exposure. Silica dust develops scar tissue inside the lungs which reduces the lungs ability to extract oxygen from the air. All miners working in underground and surface coal mines are at risk of being exposed to mine dust containing silica. In this study, cases with pathologic diagnosis of silicosis during seven years period between 2000 and 2007 were retrieved, from the pathologic file of Department of Pathology, Massih Daneshvary Hospital in Iran. Results of this case study showed the great effects of dust exposure and inhalation from the viewpoint of symptoms especially between the miners.

  16. Towards a History of Moral Education: Some Fundamental Considerations and a Case Study

    ERIC Educational Resources Information Center

    Bruneau, William Arthur

    1975-01-01

    Presents definitions and understandings of moral education, surveys some historical techniques likely to yield starting points for work on a history of moral education, and examines John Locke's theory and practice of moral education. (Author/IRT)

  17. The Potential of Crater Size Frequency Distributions for Deriving Erosion Histories: A Case Study on Mars

    NASA Astrophysics Data System (ADS)

    Wulf, G.; Hergarten, S.; Kenkmann, T.

    2015-09-01

    A recently developed software tool allows for the prediction of the impact crater record based on a given history of erosion and deposition. A first application to pedestal craters in the Medusae Fossae formation on Mars yields promising results.

  18. Towards a History of Moral Education: Some Fundamental Considerations and a Case Study

    ERIC Educational Resources Information Center

    Bruneau, William Arthur

    1975-01-01

    Presents definitions and understandings of moral education, surveys some historical techniques likely to yield starting points for work on a history of moral education, and examines John Locke's theory and practice of moral education. (Author/IRT)

  19. Pregnancy history and risk of premenopausal breast cancer-a nested case-control study.

    PubMed

    Hajiebrahimi, Mohammadhossein; Cnattingius, Sven; Lambe, Mats; Bahmanyar, Shahram

    2016-06-01

    Reproductive factors are well-known risk factors for premenopausal breast cancer (PBC). It is unknown whether these associations are modified by familial factors, including genetic and early environment factors. Using Swedish health registries, we performed a nested case-control study with two control groups: sister controls and population controls. The study population included women with live singleton births between 1973 and 2010, who also had a full sister who gave birth during this period. All women subsequently diagnosed with PBC were selected as cases (n = 8327). Sisters with the least age difference and without PBC at the time of her sister's diagnosis were selected as sister controls. For each incident case, one population control without previous PBC was selected.The population controls were individually matched with the sister controls on year of birth. Conditional logistic regression was used to estimate associations between reproductive factors and PBC. Increasing parity was inversely associated with PBC using population controls, and multiparity was a risk factor using sister controls. Very preterm delivery (≤ 31 weeks) was associated with a slightly higher PBC risk using sister controls. Preeclampsia was associated with a slightly protective effect using population controls. With respect to other factors, there were no substantial differences in risks of PBC by choice of control group. The divergent results with regard to parity and PBC risk when using sister and population controls suggest that the influence of childbearing may be modified by genotype. Selection bias when using different control groups must also be considered. © The Author 2015; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

  20. History of chickenpox in glioma risk: a report from the glioma international case-control study (GICC).

    PubMed

    Amirian, E Susan; Scheurer, Michael E; Zhou, Renke; Wrensch, Margaret R; Armstrong, Georgina N; Lachance, Daniel; Olson, Sara H; Lau, Ching C; Claus, Elizabeth B; Barnholtz-Sloan, Jill S; Il'yasova, Dora; Schildkraut, Joellen; Ali-Osman, Francis; Sadetzki, Siegal; Jenkins, Robert B; Bernstein, Jonine L; Merrell, Ryan T; Davis, Faith G; Lai, Rose; Shete, Sanjay; Amos, Christopher I; Melin, Beatrice S; Bondy, Melissa L

    2016-06-01

    Varicella zoster virus (VZV) is a neurotropic α-herpesvirus that causes chickenpox and establishes life-long latency in the cranial nerve and dorsal root ganglia of the host. To date, VZV is the only virus consistently reported to have an inverse association with glioma. The Glioma International Case-Control Study (GICC) is a large, multisite consortium with data on 4533 cases and 4171 controls collected across five countries. Here, we utilized the GICC data to confirm the previously reported associations between history of chickenpox and glioma risk in one of the largest studies to date on this topic. Using two-stage random-effects restricted maximum likelihood modeling, we found that a positive history of chickenpox was associated with a 21% lower glioma risk, adjusting for age and sex (95% confidence intervals (CI): 0.65-0.96). Furthermore, the protective effect of chickenpox was stronger for high-grade gliomas. Our study provides additional evidence that the observed protective effect of chickenpox against glioma is unlikely to be coincidental. Future studies, including meta-analyses of the literature and investigations of the potential biological mechanism, are warranted. © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

  1. Reproductive history and dietary habits and breast cancer risk in Greenlandic Inuit: a case control study.

    PubMed

    Wielsøe, M; Gudmundsdottir, S; Bonefeld-Jørgensen, E C

    2016-08-01

    The incidence of breast cancer in Greenland has increased considerably since 1970. It has been suggested that the previous low incidence is associated with the traditional lifestyle and marine food diet, and that the increase in breast cancer risk may be due to changes to a more westernized diet and lifestyle. To investigate the relation between food intake, reproductive factors and the risk of breast cancer in Greenlandic Inuit women. A case control study with participants from all regions of Greenland. The sampling was carried out at Dronning Ingrids Hospital in Nuuk, Greenland where all breast cancer cases are treated. The reproductive factors and dietary intake were assessed using a questionnaire completed at enrolment. Student t-test was used to compare group differences for continuous data. Fisher's exact test and Pearson's Chi-square were used to compare distribution frequency of data between groups. Odd ratios (ORs) were obtained using logistic regression. Estimates with a P-value ≤0.05 were considered significant. Information on reproductive factors and dietary intake was available for 116 participants, 60 breast cancer cases and 56 controls. We found that the risk of having breast cancer was significantly reduced (OR: 0.24 [95% CI 0.09; 0.66]) for the group with ≥3 full-term pregnancies and breastfeeding duration of ≥6 months compared to the group with ≤2 full-term pregnancies and breastfeeding duration of <6 months. We found that intake of fruit and vegetables when analyzed together, significantly reduced breast cancer risk (OR: 0.22 [95% CI 0.05; 0.98]). Higher parity, longer breastfeeding duration and intake of fruit and vegetables were protective factors for breast cancer risk. No clear associations between breast cancer and traditional or other imported food were seen. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  2. Building Students' Integrative Thinking Capacities: A Case Study in Economics and History

    ERIC Educational Resources Information Center

    Abbott, William; Nantz, Kathryn A.

    2012-01-01

    Having engaged in interdisciplinary team-teaching in both the two-course cluster format and the single course format, we intend to show how we helped students recognize and find their own integrative insights between the disciplines of history and economics. In the process we not only compare the advantages and disadvantages of each format but…

  3. Recovering Lost Histories of Educational Design: A Case Study in Contemporary Participatory Strategies

    ERIC Educational Resources Information Center

    Burke, Catherine; Könings, Karen D.

    2016-01-01

    Past practices shape and limit the design imagination of teachers, pupils, parents, governors, and others concerned with designing modern schools. Bringing histories of education to the table in the participatory design process of new school buildings and curricula is necessary. Schools having an extraordinary past have the potential to draw from…

  4. Recovering Lost Histories of Educational Design: A Case Study in Contemporary Participatory Strategies

    ERIC Educational Resources Information Center

    Burke, Catherine; Könings, Karen D.

    2016-01-01

    Past practices shape and limit the design imagination of teachers, pupils, parents, governors, and others concerned with designing modern schools. Bringing histories of education to the table in the participatory design process of new school buildings and curricula is necessary. Schools having an extraordinary past have the potential to draw from…

  5. Space-Time Clustering of Non-Hodgkin Lymphoma Using Residential Histories in a Danish Case-Control Study

    PubMed Central

    Baastrup Nordsborg, Rikke; Meliker, Jaymie R.; Kjær Ersbøll, Annette; Jacquez, Geoffrey M.; Raaschou-Nielsen, Ole

    2013-01-01

    Non-Hodgkin lymphoma (NHL) is a frequent cancer and incidence rates have increased markedly during the second half of the 20th century; however, the few established risk factors cannot explain this rise and still little is known about the aetiology of NHL. Spatial analyses have been applied in an attempt to identify environmental risk factors, but most studies do not take human mobility into account. The aim of this study was to identify clustering of NHL in space and time in Denmark, using 33 years of residential addresses. We utilised the nation-wide Danish registers and unique personal identification number that all Danish citizens have to conduct a register-based case-control study of 3210 NHL cases and two independent control groups of 3210 each. Cases were identified in the Danish Cancer Registry and controls were matched by age and sex and randomly selected from the Civil Registration System. Residential addresses of cases and controls from 1971 to 2003 were collected from the Civil Registration System and geocoded. Data on pervious hospital diagnoses and operations were obtained from the National Patient Register. We applied the methods of the newly developed Q-statistics to identify space-time clustering of NHL. All analyses were conducted with each of the two control groups, and we adjusted for previous history of autoimmune disease, HIV/AIDS or organ transplantation. Some areas with statistically significant clustering were identified; however, results were not consistent across the two control groups; thus we interpret the results as chance findings. We found no evidence for clustering of NHL in space and time using 33 years of residential histories, suggesting that if the rise in incidence of NHL is a result of risk factors that vary across space and time, the spatio-temporal variation of such factors in Denmark is too small to be detected with the applied method. PMID:23560108

  6. Exploring Gaps of Family History Documentation in EHR for Precision Medicine -A Case Study of Familial Hypercholesterolemia Ascertainment

    PubMed Central

    Mehrabi, Saeed; Wang, Yanshan; Ihrke, Donna; Liu, Hongfang

    2016-01-01

    In the era of precision medicine, accurately identifying familial conditions is crucial for providing target treatment. However, it is challenging to identify familial conditions without detailed family history information. In this work, we studied the documentation of family history of premature cardiovascular disease and hypercholesterolemia. The information on patients’ family history of stroke within the Patient-provided information (PPI) forms was compared with the information gathered by clinicians in clinical notes. The agreement between PPI and clinical notes on absence of family history information in PPI was substantially higher compared to presence of family history. PMID:27570664

  7. A case study of systemic curricular reform: A forty-year history

    NASA Astrophysics Data System (ADS)

    Laubach, Timothy Alan

    What follows is a description of the development of a particular inquiry-based elementary school science curriculum program and how its theoretical underpinnings positively influenced a school district's (K-12) science program and also impacted district- and state-wide curriculum reform initiatives. The district's science program has evolved since the inception of the inquiry-based elementary school science curriculum reform forty years ago. Therefore, a historical case study, which incorporated grounded theory methodology, was used to convey the forty-year development of a science curriculum reform effort and its systemic influences. Data for this study were collected primarily through artifacts, such as technical and non-technical documents, and supported and augmented with interviews. Fifteen people comprised the interview consortium with professional responsibilities including (a) administrative roles, such as superintendents, assistant superintendents, principals, and curriculum consultants/coordinators; (b) classroom roles, such as elementary and secondary school teachers who taught science; (c) partnership roles, such as university faculty who collaborated with those in administrative and classroom positions within the district; and (d) the co-director of SCIS who worked with the SCIS trial center director. Data were analyzed and coded using the constant comparative method. The analysis of data uncovered five categories or levels in which the curriculum reform evolved throughout its duration. These themes are Initiation, Education, Implementation, Confirmation, and Continuation. These five categories lead to several working hypotheses that supported the sustaining and continuing of a K-12 science curriculum reform effort. These components are a committed visionary; a theory base of education; forums promoting the education of the theory base components; shared-decision making; a university-school partnership; a core group of committed educators and teachers

  8. Stress history controls the spatial pattern of aftershocks: case studies from strike-slip earthquakes

    NASA Astrophysics Data System (ADS)

    Utkucu, Murat; Durmuş, Hatice; Nalbant, Süleyman

    2017-09-01

    Earthquake ruptures perturb stress within the surrounding crustal volume and as it is widely accepted now these stress perturbations strongly correlates with the following seismicity. Here we have documented five cases of the mainshock-aftershock sequences generated by the strike-slip faults from different tectonic environments of world in order to demonstrate that the stress changes resulting from large preceding earthquakes decades before effect spatial distribution of the aftershocks of the current mainshocks. The studied mainshock-aftershock sequences are the 15 October 1979 Imperial Valley earthquake ( Mw = 6.4) in southern California, the 27 November 1979 Khuli-Boniabad ( Mw = 7.1), the 10 May 1997 Qa'enat ( Mw = 7.2) and the 31 March 2006 Silakhor ( Mw = 6.1) earthquakes in Iran and the 13 March 1992 Erzincan earthquake ( Mw = 6.7) in Turkey. In the literature, we have been able to find only these mainshocks that are mainly characterized by dense and strong aftershock activities along and beyond the one end of their ruptures while rare aftershock occurrences with relatively lower magnitude reported for the other end of their ruptures. It is shown that the stress changes resulted from earlier mainshock(s) that are close in both time and space might be the reason behind the observed aftershock patterns. The largest aftershocks of the mainshocks studied tend to occur inside the stress-increased lobes that were also stressed by the background earthquakes and not to occur inside the stress-increased lobes that fall into the stress shadow of the background earthquakes. We suggest that the stress shadows of the previous mainshocks may persist in the crust for decades to suppress aftershock distribution of the current mainshocks. Considering active researches about use of the Coulomb stress change maps as a practical tool to forecast spatial distribution of the upcoming aftershocks for earthquake risk mitigation purposes in near-real time, it is further suggested

  9. Stress history controls the spatial pattern of aftershocks: case studies from strike-slip earthquakes

    NASA Astrophysics Data System (ADS)

    Utkucu, Murat; Durmuş, Hatice; Nalbant, Süleyman

    2016-09-01

    Earthquake ruptures perturb stress within the surrounding crustal volume and as it is widely accepted now these stress perturbations strongly correlates with the following seismicity. Here we have documented five cases of the mainshock-aftershock sequences generated by the strike-slip faults from different tectonic environments of world in order to demonstrate that the stress changes resulting from large preceding earthquakes decades before effect spatial distribution of the aftershocks of the current mainshocks. The studied mainshock-aftershock sequences are the 15 October 1979 Imperial Valley earthquake (Mw = 6.4) in southern California, the 27 November 1979 Khuli-Boniabad (Mw = 7.1), the 10 May 1997 Qa'enat (Mw = 7.2) and the 31 March 2006 Silakhor (Mw = 6.1) earthquakes in Iran and the 13 March 1992 Erzincan earthquake (Mw = 6.7) in Turkey. In the literature, we have been able to find only these mainshocks that are mainly characterized by dense and strong aftershock activities along and beyond the one end of their ruptures while rare aftershock occurrences with relatively lower magnitude reported for the other end of their ruptures. It is shown that the stress changes resulted from earlier mainshock(s) that are close in both time and space might be the reason behind the observed aftershock patterns. The largest aftershocks of the mainshocks studied tend to occur inside the stress-increased lobes that were also stressed by the background earthquakes and not to occur inside the stress-increased lobes that fall into the stress shadow of the background earthquakes. We suggest that the stress shadows of the previous mainshocks may persist in the crust for decades to suppress aftershock distribution of the current mainshocks. Considering active researches about use of the Coulomb stress change maps as a practical tool to forecast spatial distribution of the upcoming aftershocks for earthquake risk mitigation purposes in near-real time, it is further suggested that

  10. The star formation history of low-mass disk galaxies: A case study of NGC 300

    NASA Astrophysics Data System (ADS)

    Kang, Xiaoyu; Zhang, Fenghui; Chang, Ruixiang; Wang, Lang; Cheng, Liantao

    2016-01-01

    Context. Since NGC 300 is a bulgeless, isolated low-mass galaxy and it has not experienced radial migration during its evolution history, it can be treated as an ideal laboratory to test the simple galactic chemical evolution model. Aims: Our main aim is to investigate the main properties of the star formation history (SFH) of NGC 300 and compare its SFH with that of M 33 to explore the common properties and differences between these two nearby low-mass systems. Methods: We construct a simple chemical evolution model for NGC 300, assuming its disk forms gradually from continuous accretion of primordial gas and including the gas-outflow process. The model allows us to build a bridge between the SFH and observed data of NGC 300, in particular, the present-day radial profiles and global observed properties (e.g., cold gas mass, star formation rate, and metallicity). By means of comparing the model predictions with the corresponding observations, we adopt the classical χ2 methodology to find out the best combination of free parameters a, b, and bout. Results: Our results show that by assuming an inside-out formation scenario and an appropriate outflow rate, our model reproduces well most of the present-day observational values. The model not only reproduces well the radial profiles, but also the global observational data for the NGC 300 disk. Our results suggest that NGC 300 may experience a rapid growth of its disk. Through comparing the best-fitting, model-predicted SFH of NGC 300 with that of M 33, we find that the mean stellar age of NGC 300 is older than that of M 33 and there is a recent lack of primordial gas infall onto the disk of NGC 300. Our results also imply that the local environment may play a key role in the secular evolution of galaxy disks.

  11. The Case for Natural History

    NASA Astrophysics Data System (ADS)

    King, Heather; Achiam, Marianne

    2017-03-01

    Fundamental knowledge of natural history is lacking in many western societies, as demonstrated by its absence in school science curricula. And yet, to meet local and global challenges such as environmental degradation, biodiversity loss and climate change, we need to better understand the living and non-living parts of the natural world. Many have argued passionately for an increased understanding of natural history; others have developed successful pedagogical programmes for applying knowledge of natural history in environmental initiatives. In joining wider calls, we choose here to focus on the educational value afforded by understanding the epistemological bases of natural history and its particular forms of reasoning. We also briefly discuss the ways in which an education in natural history provides the foundation for environmental and social justice efforts that directly affect the lives of young people and their communities. We end by highlighting the ease by which natural history may be incorporated in learning opportunities both in and outside of the classroom.

  12. Case Study Teaching

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman

    2011-01-01

    This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)

  13. Case Study Teaching

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman

    2011-01-01

    This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)

  14. The Case for "Big History."

    ERIC Educational Resources Information Center

    Christian, David

    1991-01-01

    Urges an approach to the teaching of history that takes the largest possible perspective, crossing time as well as space. Discusses the problems and advantages of such an approach. Describes a course on "big" history that begins with time, creation myths, and astronomy, and moves on to paleontology and evolution. (DK)

  15. The Case for "Big History."

    ERIC Educational Resources Information Center

    Christian, David

    1991-01-01

    Urges an approach to the teaching of history that takes the largest possible perspective, crossing time as well as space. Discusses the problems and advantages of such an approach. Describes a course on "big" history that begins with time, creation myths, and astronomy, and moves on to paleontology and evolution. (DK)

  16. Epidemiology of sociodemographic characteristics, lifestyle, medical history, and colon cancer: a case-control study among French Canadians in Montreal.

    PubMed

    Ghadirian, P; Maisonneuve, P; Perret, C; Lacroix, A; Boyle, P

    1998-01-01

    Colon cancer is the second most common cancer in both men and women in North America and other developed countries. In a population-based case-control study of colon cancer among French Canadians in greater Montreal, a total of 402 cases and 668 controls were interviewed. The cancer cases were identified through the admission offices of five major Francophone teaching hospitals in Montreal from 1989 to 1993. The controls, matched by age, sex, place of residence, and language, were selected by a modified random digit dialing method. The results show that subjects who had ever been married had a lower risk for colon cancer (odds ratio [OR]: 0.58; 95% confidence interval [95% CI]: 0.48-0.84) than did individuals who had never been married. A significant association (OR: 1.90; p for trend = 0.003) was found between the height of subjects and the risk of colon cancer. The OR for individuals with a family history of colorectal cancer was 2.78 with a p value of 0.01. A direct and significant association (OR: 2.01) was found among constipation, use of laxatives (OR: 1.41), and the risk of colon cancer. Among women, a suggestive inverse association was detected between the number of full-term pregnancies and the risk of colon cancer in female subjects (the OR for five or more pregnancies was 0.58 with a p for trend of 0.08). There was also a suggestive linear trend (increased age-decreased risk) between age at menarche and the risk of colon cancer. No association was apparent between other sociodemographic characteristics and the risk of colon cancer. In conclusion, married individuals had lower risk for colon cancer, perhaps due to food habits or other characteristics of being single. Higher height and weight history 10 years before the diagnosis of cancer are risk factors for breast cancer, while both current weight and body mass index seem to be protective. Positive family history of colon cancer increased the risk of colon cancer significantly.

  17. Association of history of allergies and influenza-like infections with laryngeal cancer in a case-control study.

    PubMed

    Filippidis, Filippos T; Schwartz, Stephen M; Becker, Nikolaus; Dyckhoff, Gerhard; Kirschfink, Michael; Dietz, Andreas; Becher, Heiko; Ramroth, Heribert

    2015-08-01

    Prior studies suggest that history of allergy and infections early in life might be inversely associated with cancer. We explored the association between allergies, recent influenza infections and laryngeal cancer risk. We used data from a case-control study which included 229 cases of laryngeal cancer and 769 population controls matched for age and sex. History of a physician-diagnosed allergy, influenza-like infections in the past 5 years, smoking, alcohol consumption and occupational exposure to carcinogens were self-reported. Allergies were classified into two groups (Type I and Type IV), according to the underlying immunologic mechanism. Conditional logistic regression models were fitted using laryngeal cancer as the outcome, adjusting for smoking, alcohol consumption and occupational exposure and stratified for age and sex. Having any allergy was not associated significantly with laryngeal cancer. Although Type I and Type IV allergies were non-significantly associated with laryngeal cancer, Type IV allergies showed a strong inverse association after adjusting for smoking and alcohol (OR 0.50, 95 % CI 0.22-1.2). Participants who reported at least one influenza-like infection during the past 5 years were significantly less likely to have laryngeal cancer (OR 0.57, 95 % CI 0.39-0.81). After considering fever (≥38.5 °C) as a criterion for influenza infection, the association between influenza infection and laryngeal cancer was even stronger (OR 0.29, 95 % CI 0.13-0.63). We found no significant association between any allergy and laryngeal cancer, some indication of an inverse association between Type IV allergy and laryngeal cancer, whereas recent influenza infections were inversely associated with laryngeal cancer risk.

  18. Assessing spatio-temporal variability of risk surfaces using residential history data in a case control study of breast cancer

    PubMed Central

    Han, Daikwon; Rogerson, Peter A; Bonner, Matthew R; Nie, Jing; Vena, John E; Muti, Paola; Trevisan, Maurizio; Freudenheim, Jo L

    2005-01-01

    Background Most analyses of spatial clustering of disease have been based on either residence at the time of diagnosis or current residence. An underlying assumption in these analyses is that residence can be used as a proxy for environmental exposure. However, exposures earlier in life and not just those in the most recent period may be of significance. In breast cancer, there is accumulating evidence that early life exposures may contribute to risk. We explored spatio-temporal patterns of risk surfaces using data on lifetime residential history in a case control study of breast cancer, and identified elevated areas of risk and areas potentially having more exposure opportunities, defined as risk surfaces in this study. This approach may be more relevant in understanding the environmental etiology of breast cancer, since lifetime cumulative exposures or exposures at critical times may be more strongly associated with risk for breast cancer than exposures from the recent period. Results A GIS-based exploratory spatial analysis was applied, and spatio-temporal variability of those risk surfaces was evaluated using the standardized difference in density surfaces between cases and controls. The significance of the resulting risk surfaces was tested and reported as p-values. These surfaces were compared for premenopausal and postmenopausal women, and were obtained for each decade, from the 1940s to 1990s. We found strong evidence of clustering of lifetime residence for premenopausal women (for cases relative to controls), and a less strong suggestion of such clustering for postmenopausal women, and identified a substantial degree of temporal variability of the risk surfaces. Conclusion We were able to pinpoint geographic areas with higher risk through exploratory spatial analyses, and to assess temporal variability of the risk surfaces, thus providing a working hypothesis on breast cancer and environmental exposures. Geographic areas with higher case densities need

  19. Just One of the Boys? A Life History Case Study of a Male Physical Education Teacher

    ERIC Educational Resources Information Center

    Wedgwood, Nikki

    2005-01-01

    Studies of physical education teacher training have already established that hegemonic forms of masculinity are reinforced and reproduced both in the hidden curriculum (Flintoff, 1997) and the informal student culture (Skelton, 1993). Given this, an important feminist concern is whether male PE teachers whose own masculine identities are anchored…

  20. Who Should Control Indian Education? A History, Three Case Studies, Recommendations.

    ERIC Educational Resources Information Center

    McKinley, Francis; And Others

    Conducted in 1967 by the Far West Laboratory for Educational Research and Development at the request of the National Indian Youth Council, this 1-year study was made on American Indians at the following sites; Loneman, South Dakota; Ponca City, Oklahoma; Crow Agency, Montana; Fort Berthold, North Dakota; Nondalton, Alaska; South Nek Nek, Alaska;…

  1. Teaching Traumatic History to Young Children: The Case of Holocaust Studies in Israeli Kindergartens

    ERIC Educational Resources Information Center

    Ziv, Yair; Golden, Deborah; Goldberg, Tsafrir

    2015-01-01

    Recently, the Israeli Ministry of Education initiated a mandatory nationwide curriculum for Jewish kindergarten children focusing on the study of the Holocaust. This initiative raises general questions regarding the inclusion of sensitive historical issues in curricula for young children. In this article, we use the new Holocaust curriculum as an…

  2. Searching Electronic Health Records for Temporal Patterns in Patient Histories: A Case Study with Microsoft Amalga

    PubMed Central

    Plaisant, Catherine; Lam, Stanley; Shneiderman, Ben; Smith, Mark S.; Roseman, David; Marchand, Greg; Gillam, Michael; Feied, Craig; Handler, Jonathan; Rappaport, Hank

    2008-01-01

    As electronic health records (EHR) become more widespread, they enable clinicians and researchers to pose complex queries that can benefit immediate patient care and deepen understanding of medical treatment and outcomes. However, current query tools make complex temporal queries difficult to pose, and physicians have to rely on computer professionals to specify the queries for them. This paper describes our efforts to develop a novel query tool implemented in a large operational system at the Washington Hospital Center (Microsoft Amalga, formerly known as Azyxxi). We describe our design of the interface to specify temporal patterns and the visual presentation of results, and report on a pilot user study looking for adverse reactions following radiology studies using contrast. PMID:18999158

  3. From Cottages to Corporations: A Case Study in American History. Perspectives.

    ERIC Educational Resources Information Center

    Procter and Gamble Educational Services, Cincinnati, OH.

    This study unit, one in a series of eight, gives students examples of: (1) how a major business began in the mid-nineteenth century; (2) why and how individuals joined in financing and sharing in the growth of such a firm; and (3) how trademarks and brand names were adopted as a symbol that a firm stood behind and took pride in its goods and…

  4. From Cottages to Corporations: A Case Study in American History. Perspectives.

    ERIC Educational Resources Information Center

    Procter and Gamble Educational Services, Cincinnati, OH.

    This study unit, one in a series of eight, gives students examples of: (1) how a major business began in the mid-nineteenth century; (2) why and how individuals joined in financing and sharing in the growth of such a firm; and (3) how trademarks and brand names were adopted as a symbol that a firm stood behind and took pride in its goods and…

  5. History of gonorrhea and prostate cancer in a population-based case-control study in Mexico.

    PubMed

    Vázquez-Salas, Ruth Argelia; Torres-Sánchez, Luisa; López-Carrillo, Lizbeth; Romero-Martínez, Martín; Manzanilla-García, Hugo A; Cruz-Ortíz, Carlos Humberto; Mendoza-Peña, Fernando; Jiménez-Ríos, Miguel Ángel; Rodríguez-Covarrubias, Francisco; Hernández-Toríz, Narciso; Moreno-Alcázar, Othón

    2016-02-01

    We evaluated the association between a history of sexually transmitted diseases (STDs) and the risk for prostate cancer (PC) among Mexican males. PC incident cases (n=402) that were identified at six public hospitals in Mexico City were matched by age (±5 years) with 805 population controls with no history of PC. By face-to-face interview, we obtained information about sexual history, previous STDs, sociodemographic characteristics, and familial history of PC. An unconditional logistic regression model was used to estimate the risk for PC. A total of 16.6% of men reported having had at least one previous STD, and the most frequently reported STD was gonorrhea (10.5%). After adjusting by PC familial history, the history of STD was associated with a two-fold greater risk of PC: odds ratio (OR)=2.67; 95% confidence interval (95% CI=1.91-3.73). When each STD was evaluated separately, only gonorrhea was associated with a significant increase in PC risk (OR=3.04; 95% CI=1.99-4.64). These associations were similar when we stratified by low-risk PC (Gleason <7) and high-risk PC (Gleason ≥7). These results confirm that STDs, and particularly gonorrhea, may play an etiological role in PC among Mexican males, which is consistent with a previous report from a multiethnic cohort. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Designs that lacked inherent safety: case histories.

    PubMed

    Sanders, Roy E

    2003-11-14

    The fundamentals of Inherently Safer Design were not fully appreciated in the initial design (or re-design) in the following series of case histories. Two case histories involving the basic element of plant layout to minimize property damages and injury will be covered first. Simple physical separation could have reduced the losses. A case history that occurred in a bulk chemical terminal tank farm will highlight designs which allowed incompatible chemicals to react, create a fire and a lingering toxic gas release. The combination of these chemicals caused equipment damage in one case and a threat to the public in another case. This paper will conclude with case histories involving poor piping design or poorly identified piping systems, which needlessly resulted in expensive repairs. Exercising the principles of inherent safety would have reduced the severity and perhaps the opportunity of these events. We must employ the techniques of inherent safety to improve our performance.

  7. Known glioma risk loci are associated with glioma with a family history of brain tumours -- a case-control gene association study.

    PubMed

    Melin, Beatrice; Dahlin, Anna M; Andersson, Ulrika; Wang, Zhaoming; Henriksson, Roger; Hallmans, Göran; Bondy, Melissa L; Johansen, Christoffer; Feychting, Maria; Ahlbom, Anders; Kitahara, Cari M; Wang, Sophia S; Ruder, Avima M; Carreón, Tania; Butler, Mary Ann; Inskip, Peter D; Purdue, Mark; Hsing, Ann W; Mechanic, Leah; Gillanders, Elizabeth; Yeager, Meredith; Linet, Martha; Chanock, Stephen J; Hartge, Patricia; Rajaraman, Preetha

    2013-05-15

    Familial cancer can be used to leverage genetic association studies. Recent genome-wide association studies have reported independent associations between seven single nucleotide polymorphisms (SNPs) and risk of glioma. The aim of this study was to investigate whether glioma cases with a positive family history of brain tumours, defined as having at least one first- or second-degree relative with a history of brain tumour, are associated with known glioma risk loci. One thousand four hundred and thirty-one glioma cases and 2,868 cancer-free controls were identified from four case-control studies and two prospective cohorts from USA, Sweden and Denmark and genotyped for seven SNPs previously reported to be associated with glioma risk in case-control designed studies. Odds ratios were calculated by unconditional logistic regression. In analyses including glioma cases with a family history of brain tumours (n = 104) and control subjects free of glioma at baseline, three of seven SNPs were associated with glioma risk: rs2736100 (5p15.33, TERT), rs4977756 (9p21.3, CDKN2A-CDKN2B) and rs6010620 (20q13.33, RTEL1). After Bonferroni correction for multiple comparisons, only one marker was statistically significantly associated with glioma risk, rs6010620 (ORtrend for the minor (A) allele, 0.39; 95% CI: 0.25-0.61; Bonferroni adjusted ptrend , 1.7 × 10(-4) ). In conclusion, as previously shown for glioma regardless of family history of brain tumours, rs6010620 (RTEL1) was associated with an increased risk of glioma when restricting to cases with family history of brain tumours. These findings require confirmation in further studies with a larger number of glioma cases with a family history of brain tumours. Copyright © 2012 UICC.

  8. Known glioma risk loci are associated with glioma with a family history of brain tumours - a case-control gene association study

    PubMed Central

    Melin, Beatrice; Dahlin, Anna M.; Andersson, Ulrika; Wang, Zhaoming; Henriksson, Roger; Hallmans, Göran; Bondy, Melissa L.; Johansen, Christoffer; Feychting, Maria; Ahlbom, Anders; Kitahara, Cari M.; Wang, Sophia S.; Ruder, Avima M.; Carreón, Tania; Butler, Mary Ann; Inskip, Peter D.; Purdue, Mark; Hsing, Ann W.; Mechanic, Leah; Gillanders, Elizabeth; Yeager, Meredith; Linet, Martha; Chanock, Stephen J.; Hartge, Patricia; Rajaraman, Preetha

    2012-01-01

    Familial cancer can be used to leverage genetic association studies. Recent genome-wide association studies have reported independent associations between seven single nucleotide polymorphisms (SNPs) and risk of glioma. The aim of this study was to investigate whether glioma cases with a positive family history of brain tumours, defined as having at least one first or second degree relative with a history of brain tumour, are associated with known glioma risk loci. 1431 glioma cases and 2868 cancer-free controls were identified from four case-control studies and two prospective cohorts from USA, Sweden, and Denmark and genotyped for seven SNPs previously reported to be associated with glioma risk in case-control designed studies. Odds ratios were calculated by unconditional logistic regression. In analyses including glioma cases with a family history of brain tumours (n=104) and control subjects free of glioma at baseline, three out of seven SNPs were associated with glioma risk; rs2736100 (5p15.33, TERT), rs4977756 (9p21.3, CDKN2A-CDKN2B), and rs6010620 (20q13.33, RTEL1). After Bonferroni correction for multiple comparisons, only one marker was statistically significantly associated with glioma risk, rs6010620 (ORtrend for the minor (A) allele, 0.39; 95% CI, 0.25–0.61; Bonferroni adjusted ptrend, 1.7×10−4). In conclusion, as previously shown for glioma regardless of family history of brain tumours, rs6010620 (RTEL1) was associated with an increased risk of glioma when restricting to cases with family history of brain tumours. These findings require confirmation in further studies with a larger number of glioma cases with a family history of brain tumours. PMID:23115063

  9. The Case for Natural History

    ERIC Educational Resources Information Center

    King, Heather; Achiam, Marianne

    2017-01-01

    Fundamental knowledge of natural history is lacking in many western societies, as demonstrated by its absence in school science curricula. And yet, to meet local and global challenges such as environmental degradation, biodiversity loss and climate change, we need to better understand the living and non-living parts of the natural world. Many have…

  10. Oilwell deliverability monitoring: A case history

    SciTech Connect

    Thrasher, T.S.; Fetkovich, E.J.; Scott, S.L.

    1994-12-31

    This paper presents a case history study that demonstrates a method to monitor wellhead deliverability performance for flowing oil wells in a manner similar to gas wells. Separator test data measured for production allocation are used along with the material balance relationship and multiphase flow analysis to develop a wellhead backpressure curve for flowing oil wells. An equivalent wellhead static pressure for flowing oil wells is described and shown to be a function of reservoir depletion and multiphase flow rate. Determination of the equivalent wellhead static pressure extends the understanding of wellhead backpressure analysis for both flowing oil and flowing gas wells.

  11. Temporal Visualization for Legal Case Histories.

    ERIC Educational Resources Information Center

    Harris, Chanda; Allen, Robert B.; Plaisant, Catherine; Shneiderman, Ben

    1999-01-01

    Discusses visualization of legal information using a tool for temporal information called "LifeLines." Explores ways "LifeLines" could aid in viewing the links between original case and direct and indirect case histories. Uses the case of Apple Computer, Inc. versus Microsoft Corporation and Hewlett Packard Company to…

  12. Temporal Visualization for Legal Case Histories.

    ERIC Educational Resources Information Center

    Harris, Chanda; Allen, Robert B.; Plaisant, Catherine; Shneiderman, Ben

    1999-01-01

    Discusses visualization of legal information using a tool for temporal information called "LifeLines." Explores ways "LifeLines" could aid in viewing the links between original case and direct and indirect case histories. Uses the case of Apple Computer, Inc. versus Microsoft Corporation and Hewlett Packard Company to…

  13. Travel history and malaria infection risk in a low-transmission setting in Ethiopia: a case control study

    PubMed Central

    2013-01-01

    Background Malaria remains the leading communicable disease in Ethiopia, with around one million clinical cases of malaria reported annually. The country currently has plans for elimination for specific geographic areas of the country. Human movement may lead to the maintenance of reservoirs of infection, complicating attempts to eliminate malaria. Methods An unmatched case–control study was conducted with 560 adult patients at a Health Centre in central Ethiopia. Patients who received a malaria test were interviewed regarding their recent travel histories. Bivariate and multivariate analyses were conducted to determine if reported travel outside of the home village within the last month was related to malaria infection status. Results After adjusting for several known confounding factors, travel away from the home village in the last 30 days was a statistically significant risk factor for infection with Plasmodium falciparum (AOR 1.76; p=0.03) but not for infection with Plasmodium vivax (AOR 1.17; p=0.62). Male sex was strongly associated with any malaria infection (AOR 2.00; p=0.001). Conclusions Given the importance of identifying reservoir infections, consideration of human movement patterns should factor into decisions regarding elimination and disease prevention, especially when targeted areas are limited to regions within a country. PMID:23347703

  14. The Case for Digitizing Fiction with History.

    ERIC Educational Resources Information Center

    Shires, Nancy Patterson

    2002-01-01

    Including relevant fiction along with digitized history helps the reader to deal effectively with the various letters, photos, and census records or the individual pieces of history revealed. For educational, social, psychological, and biological reasons, fiction is important in the study of history. Not only can novels and stories be valuable…

  15. The Case for Digitizing Fiction with History.

    ERIC Educational Resources Information Center

    Shires, Nancy Patterson

    2002-01-01

    Including relevant fiction along with digitized history helps the reader to deal effectively with the various letters, photos, and census records or the individual pieces of history revealed. For educational, social, psychological, and biological reasons, fiction is important in the study of history. Not only can novels and stories be valuable…

  16. Winnipegosis case history: Tableland Saskatchewan

    SciTech Connect

    Orr, N.E.; Martindale, W.

    1988-02-01

    The geology and history of exploration in the Tableland area of southeast Saskatchewan will be reviewed in relation to a major Middle Devonian Winnipegosis oil discovery made in 1986 by Home Oil. Southern Saskatchewan is underlain by the northern third of the Williston basin. Although rich oil deposits have been found in the Devonian of the basin on the American side, dry holes have been the rule in Saskatchewan except for the Hummingbird Upper Devonian Birdbear discovery in 1966. The long history of failures in the Winnipegosis Formation had led to a general reluctance in the industry to drill deep wells especially with today's lower crude prices. Based on geology, seismic data, and modeling, Home Oil drilled Tableland 08-22-002-09W2M in february 1986 and encountered an oil-bearing Winnipegosis reef. This well has the highest production rate of any well in Saskatchewan and is the first commercially significant Winnipegosis well in a basinal setting within the Williston basin. A state-of-the-art pseudo 3-D processing of all the existing 2-D seismic data was performed to aid in choosing development well locations. As a result of this discovery, deep exploration plays in southeast Saskatchewan are now being pursued aggressively by many companies.

  17. Lesson Study and History Education

    ERIC Educational Resources Information Center

    Halvorsen, Anne-Lise; Kesler Lund, Alisa

    2013-01-01

    This article examines the experiences of a group of fifth-grade teachers who used lesson study, a teacher-driven form of professional development, to teach history in a project supported by a Teaching American History Grant. The project addressed the following questions: What does a lesson study cycle for history education look like? What…

  18. Lesson Study and History Education

    ERIC Educational Resources Information Center

    Halvorsen, Anne-Lise; Kesler Lund, Alisa

    2013-01-01

    This article examines the experiences of a group of fifth-grade teachers who used lesson study, a teacher-driven form of professional development, to teach history in a project supported by a Teaching American History Grant. The project addressed the following questions: What does a lesson study cycle for history education look like? What…

  19. Oilwell deliverability monitoring: A case history

    SciTech Connect

    Thrasher, T.S.; Fetkovich, E.J.; Scott, S.L.

    1995-11-01

    This paper presents a case history study that demonstrates a method to monitor wellhead-deliverability performance for flowing oil wells in a manner similar to gas wells. Separator test data measured for production allocation are used along with the material-balance relationship and multiphase-flow analysis to develop a wellhead backpressure curve for flowing oil wells. An equivalent wellhead static pressure for flowing oil wells is described and shown to be a function of reservoir depletion and multiphase-flow rate. Determination of the equivalent wellhead static pressure extends the understanding of wellhead backpressure analysis for both flowing oil and gas wells. A case history example demonstrating the application of the methods described in the paper is developed with the separator test data from Point Arguello field wells. The resulting wellhead backpressure curves clearly defined individual well deliverability and proved to be valuable diagnostic tools to monitor well performance and to quantify production potential. The authors show that the procedures developed in this paper are directly equivalent to procedures applied to conventional gaswell wellhead backpressure analysis commonly used in the industry to monitor gaswell performance. By monitoring flowing oilwell performance with the methods described in this paper, operators can address the challenge of maintaining well productivity and field production plateau.

  20. Family history and risk of ductal carcinoma in situ and triple negative breast cancer in a Han Chinese population: a case-control study.

    PubMed

    Zhou, Wenbin; Pan, Hong; Liang, Mengdi; Xia, Kai; Liang, Xiuqing; Xue, Jinqiu; Cheng, Lin; Xue, Jialei; Chen, Si; Liu, Xiaoan; Ding, Qiang; Ling, Lijun; Wang, Shui

    2013-10-01

    The association between family history and risk of triple negative breast cancer and ductal carcinoma in situ (DCIS) has not been well investigated, especially in Asian populations. We investigated the association between family history and risk of DCIS or triple negative breast cancer in a Han Chinese population. A case-control study, comprising 926 breast cancer patients and 1,187 benign breast disease controls, was conducted in our hospital. Multivariate logistic regression was used to assess the relationships between family history and risk of DCIS or triple negative breast cancer. Subjects with a family history of breast cancer had higher breast cancer risk than those without a family history (odds ratio (OR) = 2.11, 95% confidence interval (CI) = 1.26 to 3.52). Family history was not significantly associated with an increased risk of DCIS (OR = 1.27, 95% CI = 0.36 to 4.46), while family history was significantly associated with an increased risk of invasive breast cancer (OR = 2.22, 95% CI = 1.32 to 3.75), irrespective of triple negative breast cancer (OR = 3.35, 95% CI = 1.43 to 7.88) or non-triple negative breast cancer (OR = 2.14, 95% CI = 1.21 to 3.80). Our results indicate that having a family history of breast cancer is associated with an increased risk of triple negative breast cancer with a magnitude of association similar to that for non-triple negative breast cancer. Furthermore, family history is not significantly associated with an increased risk of DCIS. Future cohort studies with larger sample sizes are still needed to explore these relationships.

  1. Helicopter internal noise control: Three case histories

    NASA Technical Reports Server (NTRS)

    Edwards, B. D.; Cox, C. R.

    1978-01-01

    Case histories are described in which measurable improvements in the cabin noise environments of the Bell 214B, 206B, and 222 were realized. These case histories trace the noise control efforts followed in each vehicle. Among the design approaches considered, the addition of a fluid pulsation damper in a hydraulic system and the installation of elastomeric engine mounts are highlighted. It is concluded that substantial weight savings result when the major interior noise sources are controlled by design, both in altering the noise producing mechanism and interrupting the sound transmission paths.

  2. Understanding invasion history and predicting invasive niches using genetic sequencing technology in Australia: case studies from Cucurbitaceae and Boraginaceae

    PubMed Central

    Shaik, Razia S.; Zhu, Xiaocheng; Clements, David R.; Weston, Leslie A.

    2016-01-01

    Part of the challenge in dealing with invasive plant species is that they seldom represent a uniform, static entity. Often, an accurate understanding of the history of plant introduction and knowledge of the real levels of genetic diversity present in species and populations of importance is lacking. Currently, the role of genetic diversity in promoting the successful establishment of invasive plants is not well defined. Genetic profiling of invasive plants should enhance our understanding of the dynamics of colonization in the invaded range. Recent advances in DNA sequencing technology have greatly facilitated the rapid and complete assessment of plant population genetics. Here, we apply our current understanding of the genetics and ecophysiology of plant invasions to recent work on Australian plant invaders from the Cucurbitaceae and Boraginaceae. The Cucurbitaceae study showed that both prickly paddy melon (Cucumis myriocarpus) and camel melon (Citrullus lanatus) were represented by only a single genotype in Australia, implying that each was probably introduced as a single introduction event. In contrast, a third invasive melon, Citrullus colocynthis, possessed a moderate level of genetic diversity in Australia and was potentially introduced to the continent at least twice. The Boraginaceae study demonstrated the value of comparing two similar congeneric species; one, Echium plantagineum, is highly invasive and genetically diverse, whereas the other, Echium vulgare, exhibits less genetic diversity and occupies a more limited ecological niche. Sequence analysis provided precise identification of invasive plant species, as well as information on genetic diversity and phylogeographic history. Improved sequencing technologies will continue to allow greater resolution of genetic relationships among invasive plant populations, thereby potentially improving our ability to predict the impact of these relationships upon future spread and better manage invaders possessing

  3. Understanding invasion history and predicting invasive niches using genetic sequencing technology in Australia: case studies from Cucurbitaceae and Boraginaceae.

    PubMed

    Shaik, Razia S; Zhu, Xiaocheng; Clements, David R; Weston, Leslie A

    2016-01-01

    Part of the challenge in dealing with invasive plant species is that they seldom represent a uniform, static entity. Often, an accurate understanding of the history of plant introduction and knowledge of the real levels of genetic diversity present in species and populations of importance is lacking. Currently, the role of genetic diversity in promoting the successful establishment of invasive plants is not well defined. Genetic profiling of invasive plants should enhance our understanding of the dynamics of colonization in the invaded range. Recent advances in DNA sequencing technology have greatly facilitated the rapid and complete assessment of plant population genetics. Here, we apply our current understanding of the genetics and ecophysiology of plant invasions to recent work on Australian plant invaders from the Cucurbitaceae and Boraginaceae. The Cucurbitaceae study showed that both prickly paddy melon (Cucumis myriocarpus) and camel melon (Citrullus lanatus) were represented by only a single genotype in Australia, implying that each was probably introduced as a single introduction event. In contrast, a third invasive melon, Citrullus colocynthis, possessed a moderate level of genetic diversity in Australia and was potentially introduced to the continent at least twice. The Boraginaceae study demonstrated the value of comparing two similar congeneric species; one, Echium plantagineum, is highly invasive and genetically diverse, whereas the other, Echium vulgare, exhibits less genetic diversity and occupies a more limited ecological niche. Sequence analysis provided precise identification of invasive plant species, as well as information on genetic diversity and phylogeographic history. Improved sequencing technologies will continue to allow greater resolution of genetic relationships among invasive plant populations, thereby potentially improving our ability to predict the impact of these relationships upon future spread and better manage invaders possessing

  4. Improving RDF combustion: Case histories

    SciTech Connect

    Kubin, P.Z.

    1996-09-01

    During the past ten years Ogden has acquired or took over operating of several waste-to-energy facilities using RDF technology. Based on the diversified design, construction, and operating experience, Ogden conducted a multifaceted program to understand and improve the general plant operation and in particular the combustion in these RDF plants. This program has resulted in improved combustion stability, reduced corrosion/erosion of boiler components, and lower air pollutant emission rates. The program began with a detailed evaluation of furnace design parameters and historical operating and maintenance data. This evaluation identified specific areas of concern at each plant, such as equipment with high maintenance requirements, low reliability, or high operating costs.Design parameters at the various facilities were compared to each other and to Ogden`s mass-burn plants to gain insight into combustion issues such as fuel feed, combustion air supply, flame stability, and boiler corrosion. This was followed by detailed studies of the combustion process in the plants, including furnace air flow modeling and corrosion and erosion processes in the boilers. This generated an understanding of many of the processes taking place in the furnace, and suggested opportunities for improvement.

  5. Narrative and evidence. How can case studies from the history of science support claims in the philosophy of science?

    PubMed

    Kinzel, Katherina

    2015-02-01

    A common method for warranting the historical adequacy of philosophical claims is that of relying on historical case studies. This paper addresses the question as to what evidential support historical case studies can provide to philosophical claims and doctrines. It argues that in order to assess the evidential functions of historical case studies, we first need to understand the methodology involved in producing them. To this end, an account of historical reconstruction that emphasizes the narrative character of historical accounts and the theory-laden character of historical facts is introduced. The main conclusion of this paper is that historical case studies are able to provide philosophical claims with some evidential support, but that, due to theory-ladenness, their evidential import is restricted.

  6. Case Studies Behavior Modification.

    ERIC Educational Resources Information Center

    Wark, David M.

    The case histories of five students enrolled in a university course in how to study are reported. The students ranged in age from 18 to 35, included two males and three females, and varied in school experience from no college in one case and some college in two cases to college degrees in two cases. Students were initially taught to chart their…

  7. Case History: The Spelman College Endowment

    ERIC Educational Resources Information Center

    Commonfund Institute, 2009

    2009-01-01

    This white paper presents a case history of the Spelman College endowment and how good financial management and alternative strategies for the growth of the endowment has made Spelman's one of the largest among U.S. Historically Black Colleges and Universities (HBCUs). How has Spelman College been able to grow its endowment funds to this level? A…

  8. Hazardous behavior of lithium batteries. Case histories

    NASA Technical Reports Server (NTRS)

    Marincic, N.

    1983-01-01

    Case histories were described of hazardous behavior for three different cell sizes ranging in nominal capacity from 300 mAh to 12,000 Ah. Design characteristics and other facts believed to have been responsible for the cell explosions, are presented. Obvious facts are discussed as causes for hazardous behavior of lithium batteries in general and oxyhalide batteries in particular.

  9. Life-history phenology strongly influences population vulnerability to toxicants: a case study with the mudsnail Potamopyrgus antipodarum.

    PubMed

    Coulaud, Romain; Mouthon, Jacques; Quéau, Hervé; Charles, Sandrine; Chaumot, Arnaud

    2013-08-01

    One of the main objectives of ecological risk assessment is to evaluate the effects of toxicants on ecologically relevant biological systems such as populations or communities. However, the effects of toxicants are commonly measured on selected subindividual or individual endpoints due to their specificity against chemical stressors. Introducing these effects into population models is a promising way to predict impacts on populations. The models currently employed are very simplistic, and their environmental relevance needs to be improved to establish the ecological relevance of hazard assessment. The present study with the gastropod Potamopyrgus antipodarum combines a field experimental approach with a modeling framework. It clarifies the role played by seasonal variability of life-history traits in the population's vulnerability to the alteration of individual performance, potentially due to toxic stress. The present study comprised 3 steps: 1) characterization of the seasonal variability in life-history traits of a local population over 1 yr by using in situ experiments on caged snails, coupled with a demographic follow-up; 2) development of a periodic matrix population model that visualizes the monthly variability of population dynamics; and 3) simulation of the demographic consequences of an alteration in life-history traits (i.e., fertility, juvenile, and adult survival). The results revealed that demographic impacts strongly depend on the season when alterations of individual performance occur. Model analysis showed that this seasonal variability in population vulnerability is strongly related to the phenology of the population. The authors emphasize that improving the realism of population models is a major objective for ecological risk assessment, and that taking into account species phenology in modeling approaches should be a priority. Copyright © 2013 SETAC.

  10. The Image of the 1967 War in Israeli History Textbooks as Test Case: Studying an Active Past in a Protracted Regional Conflict

    ERIC Educational Resources Information Center

    Yogev, Esther

    2012-01-01

    This article seeks to shed light on the dilemma facing history education in regions beset by a protracted, and as yet unresolved ethno-political conflict. The article will examine this issue by means of a unique test case that observes a dramatic war event in Israeli textbooks. The event in question is the Six-Day War of 1967 and the study of its…

  11. The Image of the 1967 War in Israeli History Textbooks as Test Case: Studying an Active Past in a Protracted Regional Conflict

    ERIC Educational Resources Information Center

    Yogev, Esther

    2012-01-01

    This article seeks to shed light on the dilemma facing history education in regions beset by a protracted, and as yet unresolved ethno-political conflict. The article will examine this issue by means of a unique test case that observes a dramatic war event in Israeli textbooks. The event in question is the Six-Day War of 1967 and the study of its…

  12. Elements of War and Peace in History Education in the US and Japan: A Case Study Comparison

    ERIC Educational Resources Information Center

    Langager, Mark

    2009-01-01

    History praxis can transform perceptions of the "other" by reshaping ideas about events transpiring between groups. Nevertheless, peace education research has rarely examined history teaching. This article addresses the potential for teaching peace through history teaching. After laying out a conceptual framework for understanding the…

  13. Cadmium exposure and risk of pancreatic cancer: A meta-analysis of prospective cohort studies and case-control studies among individuals without occupational exposure history

    PubMed Central

    Chen, Cheng; Xun, Pengcheng; Nishijo, Muneko; Sekikawa, Akira

    2015-01-01

    Pancreatic cancer is one of the most deadly types of cancer for both genders. Classified as a human carcinogen, cadmium has been related to diverse cancers. However, the association between cadmium exposure and the risk of pancreatic cancer is still unclear. We quantitatively reviewed the observational studies on the association of cadmium exposure with pancreatic cancer risk among individuals without occupational exposure history published through July 2014 in PubMed by using a fixed–effects model. Four prospective cohort studies (112,934 participants with 335 events) and two case-control studies (177 cases and 539 controls) were identified. The summarized relative risk (RR) with a 95% confidence interval (CI) was 2.05 (95% CI=1.58 – 2.66), comparing the highest to the lowest category of cadmium exposure. This positive association persisted in men (RR=1.78; 95% CI=1.04 – 3.05), but not in women (RR=1.02; 95% CI=0.63 – 1.65). Further research is needed to provide more solid evidence on the association of cadmium exposure with pancreatic cancer risk and to elucidate the underlying biological mechanism of the potential gender difference. PMID:26423282

  14. Cadmium exposure and risk of pancreatic cancer: a meta-analysis of prospective cohort studies and case-control studies among individuals without occupational exposure history.

    PubMed

    Chen, Cheng; Xun, Pengcheng; Nishijo, Muneko; Sekikawa, Akira; He, Ka

    2015-11-01

    Pancreatic cancer is one of the most deadly types of cancer for both genders. Classified as a human carcinogen, cadmium has been related to diverse cancers. However, the association between cadmium exposure and the risk of pancreatic cancer is still unclear. We quantitatively reviewed the observational studies on the association of cadmium exposure with pancreatic cancer risk among individuals without occupational exposure history published through July 2014 in PubMed by using a fixed-effect model. Four prospective cohort studies (112,934 participants with 335 events) and two case-control studies (177 cases and 539 controls) were identified. The summarized relative risk (RR) with a 95% confidence interval (CI) was 2.05 (95% CI = 1.58-2.66), comparing the highest to the lowest category of cadmium exposure. This positive association persisted in men (RR = 1.78, 95% CI = 1.04-3.05) but not in women (RR = 1.02, 95% CI = 0.63-1.65). Further research is needed to provide more solid evidence on the association of cadmium exposure with pancreatic cancer risk and to elucidate the underlying biological mechanism of the potential gender difference.

  15. Family history of malignant and benign thyroid diseases and risk of thyroid cancer: a population-based case-control study in New Caledonia.

    PubMed

    Leux, Christophe; Truong, Thérèse; Petit, Claire; Baron-Dubourdieu, Dominique; Guénel, Pascal

    2012-05-01

    Exceptionally high incidence rates of thyroid cancer have been observed in New Caledonia, particularly in Melanesian women, but familial aggregation of thyroid diseases in this population is unknown. We study the association between family history of malignant or benign thyroid diseases and non-medullary thyroid cancer in this country. We conducted a population-based case-control study including 332 cases with papillary or follicular carcinoma diagnosed in 1993-1999 and 412 controls, matched by sex and 5-year age-group. Thyroid cancer was associated with a history of thyroid cancer in first-degree relatives (odds ratio (OR), 3.2; 95 % CI, 1.6-6.2) and with a family history of multinodular goiter (OR, 3.6; 95 % CI, 1.9-7.0). The ORs did not change by age at diagnosis and with the number of affected relatives. The study provides evidence that the familial component of thyroid cancer is particularly strong in men. Thyroid cancer was not associated with a family history of thyroid diseases in Melanesians from the Loyalty Islands, the area with the highest incidence rates for thyroid cancer, possibly indicating a high frequency of genetic susceptibility variants and lack of genetic variation in this population subgroup. Overall our findings confirm an elevated risk of thyroid cancer in individuals with a family history of malignant or benign thyroid diseases, particularly in Melanesians where familial aggregation of thyroid cancer had never been investigated before. The study of genetic variants in candidate susceptibility genes for thyroid cancer may help clarifying the absence of an association in the subgroup of Melanesians from the Loyalty Islands.

  16. Potential pitfalls of reconstructing deep time evolutionary history with only extant data, a case study using the canidae (mammalia, carnivora).

    PubMed

    Finarelli, John A; Goswami, Anjali

    2013-12-01

    Reconstructing evolutionary patterns and their underlying processes is a central goal in biology. Yet many analyses of deep evolutionary histories assume that data from the fossil record is too incomplete to include, and rely solely on databases of extant taxa. Excluding fossil taxa assumes that character state distributions across living taxa are faithful representations of a clade's entire evolutionary history. Many factors can make this assumption problematic. Fossil taxa do not simply lead-up to extant taxa; they represent now-extinct lineages that can substantially impact interpretations of character evolution for extant groups. Here, we analyze body mass data for extant and fossil canids (dogs, foxes, and relatives) for changes in mean and variance through time. AIC-based model selection recovered distinct models for each of eight canid subgroups. We compared model fit of parameter estimates for (1) extant data alone and (2) extant and fossil data, demonstrating that the latter performs significantly better. Moreover, extant-only analyses result in unrealistically low estimates of ancestral mass. Although fossil data are not always available, reconstructions of deep-time organismal evolution in the absence of deep-time data can be highly inaccurate, and we argue that every effort should be made to include fossil data in macroevolutionary studies.

  17. Petrogenesis and geological history of a uranium source rock: a case study in northeastern Washington, U.S.A.

    USGS Publications Warehouse

    Zielinski, R.A.; Burruss, R.C.

    1991-01-01

    A small (4 km2) drainage basin in northeastern Washington contains highly uraniferous groundwater and highly uraniferous peaty sediments of Holocene age. The U is derived from granitic bedrock that underlies the entire drainage basin and that contains 9-16 ppm U. This local bedrock was studied by petrographic, chemical and isotopic methods to determine conditions of its petrogenesis and post-emplacement history that may have contributed to its present high U content and source-rock capability. The original magma was derived by anatexis of Precambrian continental crust of probable mixed metaigneous and metasedimentary character. Mineral-melt partitioning controlled the enrichment of U in chemically evolved phases of the crystallizing melt. Following emplacement in the upper crust at ???100 Ma, the pluton interacted with meteoric-hydrothermal water at ambient temperatures >300??C. Locally intense fracturing promoted alteration, and fracturing and alteration probably continued during later regional uplift in the Eocene. Regional uplift was followed by low-temperature alteration and weathering in the middle to late Tertiary. The combined result of hydrothermal alteration and low-temperature alteration and weathering was the redistribution of U from primary mineral hosts such as allanite to new sites on fracture surfaces and in secondary minerals such as hematite. Zones of highly fractured and altered rock show the most obvious evidence of this process. A model is proposed in which high-angle fractures beneath the drainage basin were the sites of Tertiary supergene enrichments of U. Recent glacio-isostatic uplift has elevated these older enriched zones to shallow levels where they are now being leached by oxidizing groundwater. The chemistry, mineralogy, texture and geological history of this U source-rock suggest criteria for locating other granitic terrane that may contain uraniferous waters and associated young surficial U deposits. The details of U distribution and

  18. Reconstructing Land Use History from Landsat Time-Series. Case study of Swidden Agriculture Intensification in Brazil

    NASA Astrophysics Data System (ADS)

    Dutrieux, L.; Jakovac, C. C.; Siti, L. H.; Kooistra, L.

    2015-12-01

    land use history mapping in the tropics and beyond. Spatial and temporal patterns were further analysed with an ecological perspective in a follow-up study. Results show that changes in land use patterns such as land use intensification and reduced agricultural expansion reflect the socio-economic transformations that occurred in the region

  19. Reconstructing land use history from Landsat time-series. Case study of a swidden agriculture system in Brazil

    NASA Astrophysics Data System (ADS)

    Dutrieux, Loïc P.; Jakovac, Catarina C.; Latifah, Siti H.; Kooistra, Lammert

    2016-05-01

    We developed a method to reconstruct land use history from Landsat images time-series. The method uses a breakpoint detection framework derived from the econometrics field and applicable to time-series regression models. The Breaks For Additive Season and Trend (BFAST) framework is used for defining the time-series regression models which may contain trend and phenology, hence appropriately modelling vegetation intra and inter-annual dynamics. All available Landsat data are used for a selected study area, and the time-series are partitioned into segments delimited by breakpoints. Segments can be associated to land use regimes, while the breakpoints then correspond to shifts in land use regimes. In order to further characterize these shifts, we classified the unlabelled breakpoints returned by the algorithm into their corresponding processes. We used a Random Forest classifier, trained from a set of visually interpreted time-series profiles to infer the processes and assign labels to the breakpoints. The whole approach was applied to quantifying the number of cultivation cycles in a swidden agriculture system in Brazil (state of Amazonas). Number and frequency of cultivation cycles is of particular ecological relevance in these systems since they largely affect the capacity of the forest to regenerate after land abandonment. We applied the method to a Landsat time-series of Normalized Difference Moisture Index (NDMI) spanning the 1984-2015 period and derived from it the number of cultivation cycles during that period at the individual field scale level. Agricultural fields boundaries used to apply the method were derived using a multi-temporal segmentation approach. We validated the number of cultivation cycles predicted by the method against in-situ information collected from farmers interviews, resulting in a Normalized Residual Mean Squared Error (NRMSE) of 0.25. Overall the method performed well, producing maps with coherent spatial patterns. We identified

  20. Disease history and medication use as risk factors for the clinical manifestation of type 1 diabetes in children and young adults: an explorative case control study.

    PubMed

    Fazeli Farsani, Soulmaz; Souverein, Patrick C; van der Vorst, Marja M J; Mantel-Teeuwisse, Aukje K; Knibbe, Catherijne A J; de Boer, Anthonius

    2014-01-01

    There is a highly variable asymptomatic period of beta cell destruction prior to the clinical presentation of type1 diabetes. It is not well known what triggers type 1 diabetes to become a clinically overt disease. This explorative study aimed to identify the association between disease history/medication use and the clinical manifestation of type 1 diabetes. An explorative case control study was conducted in the Dutch PHARMO Record Linkage System. Cases (n = 1,107) were younger than 25 years and had at least 2 insulin prescriptions between 1999 and 2009. For each case, up to 4 controls (without any prescription for the glucose lowering medications (n = 4,424)) were matched by age and sex. Conditional logistic regression analysis was used to evaluate the association between disease history/medication use in the year prior to the diagnosis of type 1 diabetes and clinical manifestation of this disease. Type1 diabetes was significantly associated with a history of mental disorder (odds ratio (OR) 8.0, 95% confidence interval (CI) 1.5-43.7), anemia (OR 5.1, 95% CI 1.1-22.9), and disease of digestive system (OR 2.6, 95% CI 1.2-5.5). The following drug exposures were significantly associated with the clinical manifestation of type 1 diabetes: "systemic hormonal preparations" (OR 1.7, 95% CI 1.1-2.6), medications for "blood and blood forming organs" (OR 1.6, 95% CI 1.1-2.6), "alimentary tract and metabolism" (OR 1.3, 95% CI 1.1-1.6), and "anti-infectives for systemic use" (OR 1.2, 95% CI 1.01-1.4). Our explorative study demonstrated that in the year prior to the presentation of type 1 diabetes in children and young adults, hospitalization for a diverse group of diseases and drug exposures were significantly more prevalent compared with age- and sex-matched diabetes-free controls.

  1. The role of occupation and a past history of malaria in the etiology of classic Kaposi's sarcoma: a case-control study in north-east Sardinia.

    PubMed Central

    Cottoni, F.; Masala, M. V.; Budroni, M.; Rosella, M.; Satta, R.; Locatelli, F.; Montesu, M. A.; De Marco, R.

    1997-01-01

    A case-control study was performed to determine the role of rural factors including occupation and previous malaria exposure in the development of classic Kaposi's sarcoma (CKS) in a high incidence area of Europe. The occurrence of CKS association with other malignancies was also examined. The results showed that the risk of having CKS was significantly increased in subjects farming cereals, while a previous history of malaria did not influence the risk of developing CKS. A near-significant increase in associated tumours was found. PMID:9400951

  2. Gas-well deliverability monitoring: Case histories

    SciTech Connect

    Thrasher, T.S.

    1995-08-01

    This paper presents practical techniques that can be used to monitor gas-well performance. These techniques, along with the routine examination of performance data, can help the engineer maintain production potential and extend well life. This paper demonstrates the importance of monitoring well performance on a regular basis through case history examples. Four types of well conditions are described: (1) deterioration in performance over time, (2) drainage area change, (3) liquid loading, and (4) tubing design constraint. This paper also discusses the use of a personal computer program as a tool to facilitate and encourage gas-well performance monitoring.

  3. A Study on the Use of History in Middle School Mathematics: The Case of Connected Mathematics Curriculum

    ERIC Educational Resources Information Center

    Haile, Tesfayohannes Kiflemariam

    2008-01-01

    This dissertation explores the use of history of mathematics in middle school mathematics. A rationale for the importance of the incorporation of historical dimensions (HD) of mathematics is provided through a review of the literature. The literature covers pedagogical, philosophical, psychological, and social issues and provides arguments for the…

  4. Case histories in pharmaceutical risk management.

    PubMed

    McCormick, Cynthia G; Henningfield, Jack E; Haddox, J David; Varughese, Sajan; Lindholm, Anders; Rosen, Susan; Wissel, Janne; Waxman, Deborah; Carter, Lawrence P; Seeger, Vickie; Johnson, Rolley E

    2009-12-01

    The development and implementation of programs in the U.S. to minimize risks and assess unintended consequences of new medications has been increasingly required by the Food and Drug Administration (FDA) since the mid 1990s. This paper provides four case histories of risk management and post-marketing surveillance programs utilized recently to address problems associated with possible abuse, dependence and diversion. The pharmaceutical sponsors of each of these drugs were invited to present their programs and followed a similar template for their summaries that are included in this article. The drugs and presenting companies were OxyContin, an analgesic marketed by Purdue Pharma L.P., Daytrana and Vyvanse, ADHD medications marketed by Shire Pharmaceuticals, Xyrem for narcolepsy marketed by Jazz Pharmaceuticals, and Subutex and Suboxone for opioid dependence marketed by Reckitt Benckiser Pharmaceuticals Inc. These case histories and subsequent discussions provide invaluable real-world examples and illustrate both the promise of risk management programs in providing a path to market and/or for keeping on the market drugs with serious potential risks. They also illustrate the limitations of such programs in actually controlling unintended consequences, as well as the challenge of finding the right balance of reducing risks without posing undue barriers to patient access. These experiences are highly relevant as the FDA increasingly requires pharmaceutical sponsors to develop and implement the more formalized and enforceable versions of the risk management term Risk Evaluation and Mitigation Strategies (REMS).

  5. The strange case of the Freudian case history: the role of long case histories in the development of psychoanalysis.

    PubMed

    Sealey, Anne

    2011-01-01

    Sigmund Freud's five long case histories have been the focus of seemingly endless fascination and criticism. This article examines how the long case-history genre developed and its impact on the professionalization of psychoanalysis. It argues that the long case histories, using a distinctive form that highlighted the peculiarities of psychoanalytic theory, served as exemplars in the discipline. In doing so, the article extends John Forrester's work on "thinking in cases" to show the practical implications of that style of reasoning. The article illustrates how the form disappeared once the theoretical basis of the movement was set. The genre never became institutionalized, although the content of the five long case histories did, because of Freud's accepted role as theoretician of psychoanalysis.

  6. Effectiveness of Using Mobile Phone Image Capture for Collecting Secondary Data: A Case Study on Immunization History Data Among Children in Remote Areas of Thailand.

    PubMed

    Jandee, Kasemsak; Kaewkungwal, Jaranit; Khamsiriwatchara, Amnat; Lawpoolsri, Saranath; Wongwit, Waranya; Wansatid, Peerawat

    2015-07-20

    Entering data onto paper-based forms, then digitizing them, is a traditional data-management method that might result in poor data quality, especially when the secondary data are incomplete, illegible, or missing. Transcription errors from source documents to case report forms (CRFs) are common, and subsequently the errors pass from the CRFs to the electronic database. This study aimed to demonstrate the usefulness and to evaluate the effectiveness of mobile phone camera applications in capturing health-related data, aiming for data quality and completeness as compared to current routine practices exercised by government officials. In this study, the concept of "data entry via phone image capture" (DEPIC) was introduced and developed to capture data directly from source documents. This case study was based on immunization history data recorded in a mother and child health (MCH) logbook. The MCH logbooks (kept by parents) were updated whenever parents brought their children to health care facilities for immunization. Traditionally, health providers are supposed to key in duplicate information of the immunization history of each child; both on the MCH logbook, which is returned to the parents, and on the individual immunization history card, which is kept at the health care unit to be subsequently entered into the electronic health care information system (HCIS). In this study, DEPIC utilized the photographic functionality of mobile phones to capture images of all immunization-history records on logbook pages and to transcribe these records directly into the database using a data-entry screen corresponding to logbook data records. DEPIC data were then compared with HCIS data-points for quality, completeness, and consistency. As a proof-of-concept, DEPIC captured immunization history records of 363 ethnic children living in remote areas from their MCH logbooks. Comparison of the 2 databases, DEPIC versus HCIS, revealed differences in the percentage of completeness and

  7. Family history and socioeconomic risk factors for non-syndromic cleft lip and palate: a matched case-control study in a less developed country.

    PubMed

    Acuña-González, Gladys; Medina-Solís, Carlo E; Maupomé, Gerardo; Escoffie-Ramírez, Mauricio; Hernández-Romano, Jesús; Márquez-Corona, María de L; Islas-Márquez, Arturo J; Villalobos-Rodelo, Juan J

    2011-01-01

    From an epidemiological point of view, non-syndromic orofacial clefts are the most common oral congenital deformities worldwide. Family histories were traced and socioeconomic risk factors were identified for non-syndromic cleft lip with or without cleft palate. A case-control study was carried out with 208 cases of non-syndromic cleft lip with or without cleft palate, and matched by age and sex with 416 controls. Cases were patients attending a referral clinic from 2002 through 2004 in Campeche, Mexico. A questionnaire was administered to collect sociodemographic and socioeconomic variables as well as familial background relevant to non-syndromic cleft lip with or without cleft palate. Conditional logistic regression models were used; adjusted odds ratios and 95% confidence intervals were calculated. In the multivariate model, the following risk factors were identified: 1) low socioeconomic status; 2) birth in the southern region of Campeche state; 3) home delivery or delivery in a publicly funded hospital; 4) occurrence of prior non-syndromic cleft lip with or without cleft palate cases in the father's or mother's family: 5) having a sibling with non-syndromic cleft lip with or without cleft palate; 6) the proband having another malformation, and 7) a history of infections during pregnancy. Prenatal care consisting of vitamin supplementation was a protective factor for non-syndromic cleft lip with or without cleft palate (odds ratio=0.29). A "social gradient in health" was seen to link oral malformation with diet components, and several socioeconomic and socio-demographic factors broadly encompassed in low socioeconomic status. Further characterization of risk factors will guide the assemblage of a pro-active counseling and prevention program for families at risk for non-syndromic cleft lip and cleft palate.

  8. Case-control study of high-speed exercise history of Thoroughbred and Quarter Horse racehorses that died related to a complete scapular fracture.

    PubMed

    Vallance, S A; Entwistle, R C; Hitchens, P L; Gardner, I A; Stover, S M

    2013-05-01

    Identification of exercise history patterns that are related to catastrophic scapular fracture will facilitate prevention of racehorse fatalities. To determine if exercise patterns are associated with scapular fracture in Thoroughbred (TB) and Quarter Horse (QH) racehorses. High-speed exercise histories for 65 TB and 26 QH racehorses that had a complete scapular fracture (cases) and 2 matched control racehorses were retrospectively studied. Exercise variables were created from lifetime race and official timed workout reports. Associations between exercise variables and scapular fracture were investigated using conditional logistic regression. Thoroughbreds with a scapular fracture had a greater number of workouts, events (combined works and races), and mean event distances than QHs with a scapular fracture. Quarter Horses worked less frequently and accumulated distance at a lower rate than TBs. Breed differences were not found for career race number or length, time between races or lay-up variables for horses with ≥1 lay-up. For both breeds, cases had fewer events, lower recent accumulated distance and fewer active days in training than controls; however, a subset of TB cases with >10 events since lay-up had a longer active career than controls. For QHs that had a lay-up, total and mean lay-up times were greater for cases than controls. Multivariable models revealed that odds ratios (OR) of scapular fracture were greater for TBs that had not yet raced (OR = 23.19; 95% confidence interval (CI) 3.03-177.38) and lower for QHs with more events (OR = 0.71; 95% CI 0.54-0.94). Racehorses that are in early high-speed training but behind that of their training cohort should be examined for signs of scapular stress remodelling. Quarter Horses that had a prolonged lay-up and TBs that have endured high-speed training for a longer duration than that of their training cohort also were at greater risk. © 2012 EVJ Ltd.

  9. [Psychiatric case history of Vincent van Gogh].

    PubMed

    van Meekeren, E

    2000-12-23

    Much has been written about Vincent van Gogh's pathological condition. Most authors base their various diagnoses on the symptoms he exhibited in the last years of his life. However, Van Gogh during a much longer part of his life displayed symptoms best consistent with a borderline (personality) disorder: impulsivity, variable moods, self-destructive behaviour, fear of abandonment, an unbalanced self-image, authority conflicts and other complicated relationships. The precipitating element disturbing Vincent's psychic balance--delicate in any case due to a positive family history, malnutrition, intoxication and exhaustion and the borderline disorder--may have been his being deserted by his friend Gauguin. He (also) developed an organic psychosyndrome with psychotic and epileptic elements. The stress (due to social isolation, by his being a psychiatric patient, and by poor prospects), the intoxication going on outside the hospitals and especially also the problems relating to his brother Theo caused a downward spiral culminating in suicide.

  10. Role of thermal history in atomic dynamics of chalcogenide glass: A case study on Ge20Te80 glass

    NASA Astrophysics Data System (ADS)

    Sharma, Yashika; Kalra, Geetanjali; Murugavel, Sevi

    2016-05-01

    The non-existence of thermodynamic equilibrium in glasses, their thermal history plays a very crucial role in explaining the relaxation behavior in various time scales and its configurational states. More importantly, the associated relaxation behavior is related mainly to the structural phenomenon of the glasses. Here, we report the dependence of quenching rate on the variation of structural units. The local structures of these glasses are monitored by recording the Raman spectroscopy and related to the different configurational states. The observed variations in structural differences are reflected in the measured density of the corresponding glasses. The quenching rate dependent of the relative fractions of edge-shared and corner-shared GeTe4 tetrahedral units are shown to be consistent with the corresponding variations in the measured density values.

  11. Effects of Including Misidentified Sharks in Life History Analyses: A Case Study on the Grey Reef Shark Carcharhinus amblyrhynchos from Papua New Guinea.

    PubMed

    Smart, Jonathan J; Chin, Andrew; Baje, Leontine; Green, Madeline E; Appleyard, Sharon A; Tobin, Andrew J; Simpfendorfer, Colin A; White, William T

    2016-01-01

    Fisheries observer programs are used around the world to collect crucial information and samples that inform fisheries management. However, observer error may misidentify similar-looking shark species. This raises questions about the level of error that species misidentifications could introduce to estimates of species' life history parameters. This study addressed these questions using the Grey Reef Shark Carcharhinus amblyrhynchos as a case study. Observer misidentification rates were quantified by validating species identifications using diagnostic photographs taken on board supplemented with DNA barcoding. Length-at-age and maturity ogive analyses were then estimated and compared with and without the misidentified individuals. Vertebrae were retained from a total of 155 sharks identified by observers as C. amblyrhynchos. However, 22 (14%) of these were sharks were misidentified by the observers and were subsequently re-identified based on photographs and/or DNA barcoding. Of the 22 individuals misidentified as C. amblyrhynchos, 16 (73%) were detected using photographs and a further 6 via genetic validation. If misidentified individuals had been included, substantial error would have been introduced to both the length-at-age and the maturity estimates. Thus validating the species identification, increased the accuracy of estimated life history parameters for C. amblyrhynchos. From the corrected sample a multi-model inference approach was used to estimate growth for C. amblyrhynchos using three candidate models. The model averaged length-at-age parameters for C. amblyrhynchos with the sexes combined were L∞ = 159 cm TL and L0 = 72 cm TL. Females mature at a greater length (l50 = 136 cm TL) and older age (A50 = 9.1 years) than males (l50 = 123 cm TL; A50 = 5.9 years). The inclusion of techniques to reduce misidentification in observer programs will improve the results of life history studies and ultimately improve management through the use of more accurate data

  12. Effects of Including Misidentified Sharks in Life History Analyses: A Case Study on the Grey Reef Shark Carcharhinus amblyrhynchos from Papua New Guinea

    PubMed Central

    Smart, Jonathan J.; Chin, Andrew; Baje, Leontine; Green, Madeline E.; Appleyard, Sharon A.; Tobin, Andrew J.; Simpfendorfer, Colin A.; White, William T.

    2016-01-01

    Fisheries observer programs are used around the world to collect crucial information and samples that inform fisheries management. However, observer error may misidentify similar-looking shark species. This raises questions about the level of error that species misidentifications could introduce to estimates of species’ life history parameters. This study addressed these questions using the Grey Reef Shark Carcharhinus amblyrhynchos as a case study. Observer misidentification rates were quantified by validating species identifications using diagnostic photographs taken on board supplemented with DNA barcoding. Length-at-age and maturity ogive analyses were then estimated and compared with and without the misidentified individuals. Vertebrae were retained from a total of 155 sharks identified by observers as C. amblyrhynchos. However, 22 (14%) of these were sharks were misidentified by the observers and were subsequently re-identified based on photographs and/or DNA barcoding. Of the 22 individuals misidentified as C. amblyrhynchos, 16 (73%) were detected using photographs and a further 6 via genetic validation. If misidentified individuals had been included, substantial error would have been introduced to both the length-at-age and the maturity estimates. Thus validating the species identification, increased the accuracy of estimated life history parameters for C. amblyrhynchos. From the corrected sample a multi-model inference approach was used to estimate growth for C. amblyrhynchos using three candidate models. The model averaged length-at-age parameters for C. amblyrhynchos with the sexes combined were  L¯∞ = 159 cm TL and  L¯0 = 72 cm TL. Females mature at a greater length (l50 = 136 cm TL) and older age (A50 = 9.1 years) than males (l50 = 123 cm TL; A50 = 5.9 years). The inclusion of techniques to reduce misidentification in observer programs will improve the results of life history studies and ultimately improve management through the use of more

  13. History of Vocational Education and Training in Europe: Cases, Concepts and Challenges. Studies in Vocational and Continuing Education. Volume 14

    ERIC Educational Resources Information Center

    Berner, Esther, Ed.; Gonon, Philipp, Ed.

    2016-01-01

    Understanding today's Vocational Education and Training (VET) systems requires a comprehension of the rise and development, i.e. of the foundations of topical VET. This book provides a comparative view of its development in Europe. The contributions of renowned authors give insight into conceptual questions, cases, and challenges in this field.

  14. Disease History and Medication Use as Risk Factors for the Clinical Manifestation of Type 1 Diabetes in Children and Young Adults: An Explorative Case Control Study

    PubMed Central

    Fazeli Farsani, Soulmaz; Souverein, Patrick C.; van der Vorst, Marja M. J.; Mantel-Teeuwisse, Aukje K.; Knibbe, Catherijne A. J.; de Boer, Anthonius

    2014-01-01

    Background There is a highly variable asymptomatic period of beta cell destruction prior to the clinical presentation of type1 diabetes. It is not well known what triggers type 1 diabetes to become a clinically overt disease. This explorative study aimed to identify the association between disease history/medication use and the clinical manifestation of type 1 diabetes. Methodology/Principal Findings An explorative case control study was conducted in the Dutch PHARMO Record Linkage System. Cases (n  = 1,107) were younger than 25 years and had at least 2 insulin prescriptions between 1999 and 2009. For each case, up to 4 controls (without any prescription for the glucose lowering medications (n  = 4,424)) were matched by age and sex. Conditional logistic regression analysis was used to evaluate the association between disease history/medication use in the year prior to the diagnosis of type1 diabetes and clinical manifestation of this disease. Type1 diabetes was significantly associated with a history of mental disorder (odds ratio (OR) 8.0, 95% confidence interval (CI) 1.5–43.7), anemia (OR 5.1, 95% CI 1.1–22.9), and disease of digestive system (OR 2.6, 95% CI 1.2–5.5). The following drug exposures were significantly associated with the clinical manifestation of type 1 diabetes: “systemic hormonal preparations” (OR 1.7, 95% CI 1.1–2.6), medications for “blood and blood forming organs” (OR 1.6, 95% CI 1.1–2.6), “alimentary tract and metabolism” (OR 1.3, 95% CI 1.1–1.6), and “anti-infectives for systemic use” (OR 1.2, 95% CI 1.01–1.4). Conclusions Our explorative study demonstrated that in the year prior to the presentation of type1 diabetes in children and young adults, hospitalization for a diverse group of diseases and drug exposures were significantly more prevalent compared with age- and sex-matched diabetes-free controls. PMID:24498320

  15. Residential history, family characteristics and non-Hodgkin lymphoma, a population-based case-control study in the San Francisco Bay Area.

    PubMed

    Bracci, Paige M; Dalvi, Tapashi B; Holly, Elizabeth A

    2006-07-01

    A population-based, case-control study (N = 1,593 cases, N = 2,515 controls) was conducted in the San Francisco Bay Area, California, to determine risk factors for non-Hodgkin lymphoma (NHL). This report examines residential characteristics, number of siblings, childhood infections, and allergic rhinitis to evaluate the association between NHL and the hygiene hypothesis. Adjusted unconditional logistic regression analyses included HIV-negative participants (N = 1,304 cases, N = 2,402 controls) ages 21 to 74 years, who completed in-person interviews. At childhood ages, odds ratios (OR) for NHL decreased with increasing number of household rooms (age 8 years, P(trend) = 0.08; age 15 years, P(trend) < 0.0001) and increased with more crowded living conditions (quartiles of no. people/no. rooms; age 8 years, P(trend) < 0.0001; age 15 years, P(trend) = 0.0004), whereas at older ages a greater number of people in the household and greater number of household rooms were positively associated with NHL. ORs increased with increasing number of siblings (P(trend) = 0.0003) and increasing birth order (P(trend) = 0.01). Participants with five or more younger siblings had a 50% increased OR for NHL. ORs for NHL decreased with an increasing number of different infections during childhood (age 8 years, P(trend) < 0.0001; age 15 years, P(trend) = 0.0003) and with history of allergic rhinitis (P < 0.0001). Our results are somewhat consistent with the hygiene hypothesis that less crowding and better sanitation results in fewer infections early in life and an increased incidence of immune-related conditions later in life. The role of the complex relationship between residential history, family characteristics, childhood infections, and immune function in the development of NHL warrants further investigation in pooled analyses.

  16. Characterizing the hypersiliceous rocks of Belgium used in (pre-)history: a case study on sourcing sedimentary quartzites

    NASA Astrophysics Data System (ADS)

    Veldeman, Isis; Baele, Jean-Marc; Goemaere, Eric; Deceukelaire, Marleen; Dusar, Michiel; De Doncker, H. W. J. A.

    2012-08-01

    Tracking raw material back to its extraction source is a crucial step for archaeologists when trying to deduce migration patterns and trade contacts in (pre-)history. Regarding stone artefacts, the main rock types encountered in the archaeological record of Belgium are hypersiliceous rocks. This is a newly introduced category of rock types comprising those rocks made of at least 90% silica. These are strongly silicified quartz sands or sedimentary quartzites, siliceous rocks of chemical and biochemical origin (e.g. flint), very pure metamorphic quartzites and siliceous volcanic rocks (e.g. obsidian). To be able to distinguish between different extraction sources, ongoing research was started to locate possible extraction sources of hypersiliceous rocks and to characterize rocks collected from these sources. Characterization of these hypersiliceous rocks is executed with the aid of optical polarizing microscopy, optical cold cathodoluminescence and scanning-electron microscopy combined with energy-dispersive x-ray spectrometry and with back-scatter electron imaging. In this paper, we focus on various sedimentary quartzites of Paleogene stratigraphical level.

  17. The impact of high-resolution biostratigraphy on reservoir prediction and basin history - A Barents Sea case study

    SciTech Connect

    Husmo, T. ); Hochuli, P. )

    1991-08-01

    The Hammerfest Basin is bounded by the Troms-Finnmark Platform to the south and the Loppa High to the north. Twenty-seven exploration wells have been drilled in the basin since 1980. The objective for most of these wells was Middle Jurassic fault blocks. Until recently little attention has been paid to the Upper Jurassic to Lower Cretaceous synrift sequence. The first well drilled on Block 7120/10 tested a rotated Jurassic fault block. This well, together with two wells in an adjacent block, penetrated thin Lower Cretaceous sands near the distal pinch-outs of fault wedges. Seismic data indicated that a basinal wedge of equivalent age was present on Block 7120/10. High risk was put on the presence of sand in this basinal wedge, and a detailed biostratigraphic analysis was performed on wells along the basin margin in order to determine the timing of erosion on the margin and whether the Jurassic-Triassic coarse clastics were present in the provenance area. The analysis separated reworked from in-situ palynomorph assemblages in the synrift succession in the analyzed wells. A clear inverted stratigraphy was displayed by the reworked palynomorphs. Furthermore, a dramatic increase in reworked palynomorphs. Furthermore, a dramatic increase in reworked palynomorphs was observed in all wells at the onset of Valanginian. In particular the presence of Nannoceratopsis gracilis suggested that shallow marine Jurassic clastics were eroded at this time. Sand presence was predicted for the basinal wedge. The understanding of the basin history was also improved. Well 71Z0/10-2 drilled summer 1990 proved the success of the reservoir prediction and hence the usefulness of incorporating biostratigraphy in the assessment.

  18. The nurse in the university: a history of university education for South african nurses: a case study of the university of the witwatersrand.

    PubMed

    Horwitz, Simonne

    2011-01-01

    This paper charts the history and debates surrounding the introduction of academic, university-based training of nurses in South Africa. This was a process that was drawn out over five decades, beginning in the late 1930s. For nurses, university training was an important part of a process of professionalization; however, for other members of the medical community, nursing was seen as being linked to women's service work. Using the case-study of the University of the Witwatersrand, one of South Africa's premier universities and the place in the country to offer a university-based nursing program, we argue that an historical understanding of the ways in which nursing education was integrated into the university system tells us a great deal about the professionalization of nursing. This paper also recognises, for the first time, the pioneers of this important process.

  19. Audio Visual Aids. Part 2; History, Social History, Social Studies.

    ERIC Educational Resources Information Center

    Educational Foundation for Visual Aids, London (England).

    Audiovisual teaching aids for history, social history, and social studies, that may be bought or rented from suppliers in Britain, are listed in this 270-page catalog. Audiovisual materials include film, filmstrips, slides, overhead projector transparencies, wallsheets, prints, records, tapes and teaching kits. Each catalog entry describes the…

  20. Integrated pipeline for inferring the evolutionary history of a gene family embedded in the species tree: a case study on the STIMATE gene family.

    PubMed

    Song, Jia; Zheng, Sisi; Nguyen, Nhung; Wang, Youjun; Zhou, Yubin; Lin, Kui

    2017-10-03

    Because phylogenetic inference is an important basis for answering many evolutionary problems, a large number of algorithms have been developed. Some of these algorithms have been improved by integrating gene evolution models with the expectation of accommodating the hierarchy of evolutionary processes. To the best of our knowledge, however, there still is no single unifying model or algorithm that can take all evolutionary processes into account through a stepwise or simultaneous method. On the basis of three existing phylogenetic inference algorithms, we built an integrated pipeline for inferring the evolutionary history of a given gene family; this pipeline can model gene sequence evolution, gene duplication-loss, gene transfer and multispecies coalescent processes. As a case study, we applied this pipeline to the STIMATE (TMEM110) gene family, which has recently been reported to play an important role in store-operated Ca(2+) entry (SOCE) mediated by ORAI and STIM proteins. We inferred their phylogenetic trees in 69 sequenced chordate genomes. By integrating three tree reconstruction algorithms with diverse evolutionary models, a pipeline for inferring the evolutionary history of a gene family was developed, and its application was demonstrated.

  1. A Critical Case Study of Selected United States History Textbooks from a Tribal Critical Race Theory Perspective

    ERIC Educational Resources Information Center

    Padgett, Gary

    2012-01-01

    The purpose of this study was to describe and explain the portrayal of American Indians in U.S. textbooks selected for review in Hillsborough County, Florida's 2012 textbook adoption. The study identified which of the textbooks under consideration contained the greatest amount of information dedicated to American Indians. The study then analyzed…

  2. A Critical Case Study of Selected United States History Textbooks from a Tribal Critical Race Theory Perspective

    ERIC Educational Resources Information Center

    Padgett, Gary

    2012-01-01

    The purpose of this study was to describe and explain the portrayal of American Indians in U.S. textbooks selected for review in Hillsborough County, Florida's 2012 textbook adoption. The study identified which of the textbooks under consideration contained the greatest amount of information dedicated to American Indians. The study then analyzed…

  3. History Through Biography? A Conceptual Research Study.

    ERIC Educational Resources Information Center

    Johns, Robert W.

    Social studies classroom teachers can enliven high school history courses and motivate students to learn about history by using dramatic or heroic biographies in teaching history. The biographical approach centers on study of the lives, beliefs, and surroundings of historical actors. This approach differs from the "great man" theory of history in…

  4. History Through Biography? A Conceptual Research Study.

    ERIC Educational Resources Information Center

    Johns, Robert W.

    Social studies classroom teachers can enliven high school history courses and motivate students to learn about history by using dramatic or heroic biographies in teaching history. The biographical approach centers on study of the lives, beliefs, and surroundings of historical actors. This approach differs from the "great man" theory of history in…

  5. Geothermal systems: Principles and case histories

    NASA Astrophysics Data System (ADS)

    Rybach, L.; Muffler, L. J. P.

    The classification of geothermal systems is considered along with the geophysical and geochemical signatures of geothermal systems, aspects of conductive heat transfer and regional heat flow, and geothermal anomalies and their plate tectonic framework. An investigation of convective heat and mass transfer in hydrothermal systems is conducted, taking into account the mathematical modelling of hydrothermal systems, aspects of idealized convective heat and mass transport, plausible models of geothermal reservoirs, and preproduction models of hydrothermal systems. Attention is given to the prospecting for geothermal resources, the application of water geochemistry to geothermal exploration and reservoir engineering, heat extraction from geothermal reservoirs, questions of geothermal resource assessment, and environmental aspects of geothermal energy development. A description is presented of a number of case histories, taking into account the low enthalpy geothermal resource of the Pannonian Basin in Hungary, the Krafla geothermal field in Northeast Iceland, the geothermal system of the Jemez Mountains in New Mexico, and extraction-reinjection at the Ahuachapan geothermal field in El Salvador.

  6. Assessing land-use history for reporting on cropland dynamics - A case study using the Land-Parcel Identification System in Ireland

    NASA Astrophysics Data System (ADS)

    Zimmermann, Jesko; González, Ainhoa; Jones, Michael; O'Brien, Phillip; Stout, Jane C.; Green, Stuart

    2016-04-01

    In developed countries, cropland and grassland conversions and management can be a major factor in Land Use and Land Use Change (LULUC) related Greenhouse Gas (GHG) dynamics. Depending on land use, management and factors such as soil properties land can either act as source or sink for GHGs. Currently many countries depend on national statistics combined with socio-economic modelling to assess current land use as well as inter-annual changes. This potentially introduces a bias as it neither provides information on direct land- use change trajectories nor spatially explicit information to assess the environmental context. In order to improve reporting countries are shifting towards high resolution spatial datasets. In this case study, we used the Land Parcel Identification System (LPIS), a pan-European geographical database developed to assist farmers and authorities with agricultural subsidies, to analyse cropland dynamics in Ireland. The database offer high spatial resolution and is updated annually. Generally Ireland is considered grassland dominated with 90 % of its agricultural area under permanent grassland, and only a small area dedicated to cropland. However an in-depth analysis of the LPIS for the years 2000 to 2012 showed strong underlying dynamics. While the annual area reported as cropland remained relatively constant at 3752.3 ± 542.3 km2, the area of permanent cropland was only 1251.9 km2. Reversely, the area that was reported as cropland for at least one year during the timeframe was 7373.4 km2, revealing a significantly higher area with cropland history than annual statistics would suggest. Furthermore, the analysis showed that one quarter of the land converting from or to cropland will return to the previous land use within a year. To demonstrate potential policy impact, we assessed cropland/grassland dynamics from the 2008 to 2012 commitment period using (a) annual statistics, and (b) data including land use history derived from LPIS. Under

  7. Examining the relationship between fire history and sudden oak death patterns: a case study in Sonoma County

    Treesearch

    Max A. Moritz; Dennis C. Odion

    2006-01-01

    Fire is often integral to forest ecology and can affect forest disease dynamics. Sudden oak death has spread across a large, fire-prone portion of California, killing large numbers of oaks and tanoaks and infecting most associated woody plants. Building on our earlier study of fire-disease dynamics, we examined spatial patterns of confirmed infections in relation to...

  8. Case Studies

    ERIC Educational Resources Information Center

    Ritter, Lois A., Ed.; Sue, Valerie M., Ed.

    2007-01-01

    This article presents two case studies using online surveys for evaluation. The authors begin with an example of a needs assessment survey designed to measure the amount of help new students at a university require in their first year. They then discuss the follow-up survey conducted by the same university to measure the effectiveness of the…

  9. Case Studies

    ERIC Educational Resources Information Center

    Ritter, Lois A., Ed.; Sue, Valerie M., Ed.

    2007-01-01

    This article presents two case studies using online surveys for evaluation. The authors begin with an example of a needs assessment survey designed to measure the amount of help new students at a university require in their first year. They then discuss the follow-up survey conducted by the same university to measure the effectiveness of the…

  10. Employment history indicators and mortality in a nested case-control study from the Spanish WORKing life social security (WORKss) cohort.

    PubMed

    López Gómez, María Andrée; Serra, Laura; Delclos, George L; Benavides, Fernando G

    2017-01-01

    Employment has transitioned from stable to more flexible schemes. Little is known about the effects of dynamic working lives and mortality. We examined the association of employment, unemployment and inactivity on mortality among workers born in 1926-1988, in a nested case-control study of workers from the Spanish WORKss cohort. Cases were all deaths that occurred during 2004-2013 and controls were living persons, matched for sex and age at the time the case occurred. We had information on employment from 1981 to 2013. Logistic regression was used to measure the associations between the 3 employment history indicators separately by sex. There were 53,989 cases and an equal number of controls (n = 107,978). More than 16 years employed showed a protective effect against mortality in women (OR = 0.88, 95%CI: 0.81, 0.94) and men (OR = 0.76, 95%CI: 0.70, 0.79). The number of spells and time in unemployment and inactivity were significantly related to mortality in men, but not women. Sensitivity analyses by labor relationship showed stronger associations of unemployment (OR = 1.42, 95%CI: 1.13, 1.78) and inactivity (OR = 1.34; 95%CI: 1.09, 1.65) for temporary workers. Employment gaps are detrimental to health and have worse effects if the gaps occur without unemployment benefits or after temporary contracts. These results may drive improvement of labor and social policies that protect workers against the potential negative effects of dynamic work lives.

  11. Lebanon: A Case of History Education in a Sectarian Society

    ERIC Educational Resources Information Center

    Yoder, Paul J.

    2015-01-01

    This paper synthesizes the extant literature on history education in Lebanon. The sectarian nature of the country and the recent civil war make the case of Lebanon a unique and compelling one. Three emerging understandings underscore the complexity of history education in Lebanon and demonstrate the ways in which history is used to undercut…

  12. Studying Russian and Soviet History.

    ERIC Educational Resources Information Center

    Ascher, Abraham, Ed.

    These essays were written to assist teachers in the task of making Russian history intelligible to young U.S. students. In "An Approach to Russian History," Edward Keenan proposes that students need to gain a better understanding of how Russians perceive themselves and their history. In "Pre-Petrine Russia," Andrzej S. Kaminski…

  13. Drug Discovery Case History: US Spelling

    PubMed Central

    Kufahl, Peter R.; Watterson, Lucas R.

    2015-01-01

    Introduction Globally, alcohol abuse and dependence are significant contributors to chronic disease and injury and are responsible for nearly 4% of all deaths annually. Acamprosate (Campral), one of only three pharmacological treatments approved for the treatment of alcohol dependence, has shown mixed efficacy in clinical trials in maintaining abstinence of detoxified alcoholics since studies began in the 1980’s. Yielding inconsistent results, these studies have prompted skepticism. Areas Covered Herein, the authors review the preclinical studies which have assessed the efficacy of acamprosate in various animal models of alcohol dependence and discuss the disparate findings from the major clinical trials. Moreover, the authors discuss the major limitations of these preclinical and clinical studies and offer explanations for the often contradictory findings. The article also looks at the importance of the calcium moiety that accompanies the salt form of acamprosate and its relevance to its activity. Expert opinion The recent discovery that large doses of calcium largely duplicate the effects of acamprosate in animal models has introduced a serious challenge to the widely-held functional association between this drug and the glutamate neurotransmission system. Future research on acamprosate or newer pharmacotherapeutics should consider assessing plasma and/or brain levels of calcium as a correlate or mediating factor in anti-relapse efficacy. Furthermore, preclinical research on acamprosate has thus far lacked animal models of chemical dependence on alcohol, and the testing of rodents with histories of alcohol intoxication and withdrawal is suggested. PMID:25258174

  14. Pitfalls of the Geographic Population Structure (GPS) Approach Applied to Human Genetic History: A Case Study of Ashkenazi Jews.

    PubMed

    Flegontov, Pavel; Kassian, Alexei; Thomas, Mark G; Fedchenko, Valentina; Changmai, Piya; Starostin, George

    2016-08-16

    In a recent interdisciplinary study, Das et al. have attempted to trace the homeland of Ashkenazi Jews and of their historical language, Yiddish (Das et al. 2016 Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz. Genome Biol Evol. 8:1132-1149). Das et al. applied the geographic population structure (GPS) method to autosomal genotyping data and inferred geographic coordinates of populations supposedly ancestral to Ashkenazi Jews, placing them in Eastern Turkey. They argued that this unexpected genetic result goes against the widely accepted notion of Ashkenazi origin in the Levant, and speculated that Yiddish was originally a Slavic language strongly influenced by Iranian and Turkic languages, and later remodeled completely under Germanic influence. In our view, there are major conceptual problems with both the genetic and linguistic parts of the work. We argue that GPS is a provenancing tool suited to inferring the geographic region where a modern and recently unadmixed genome is most likely to arise, but is hardly suitable for admixed populations and for tracing ancestry up to 1,000 years before present, as its authors have previously claimed. Moreover, all methods of historical linguistics concur that Yiddish is a Germanic language, with no reliable evidence for Slavic, Iranian, or Turkic substrata. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  15. Pitfalls of the Geographic Population Structure (GPS) Approach Applied to Human Genetic History: A Case Study of Ashkenazi Jews

    PubMed Central

    Flegontov, Pavel; Kassian, Alexei; Thomas, Mark G.; Fedchenko, Valentina; Changmai, Piya; Starostin, George

    2016-01-01

    In a recent interdisciplinary study, Das et al. have attempted to trace the homeland of Ashkenazi Jews and of their historical language, Yiddish (Das et al. 2016. Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz. Genome Biol Evol. 8:1132–1149). Das et al. applied the geographic population structure (GPS) method to autosomal genotyping data and inferred geographic coordinates of populations supposedly ancestral to Ashkenazi Jews, placing them in Eastern Turkey. They argued that this unexpected genetic result goes against the widely accepted notion of Ashkenazi origin in the Levant, and speculated that Yiddish was originally a Slavic language strongly influenced by Iranian and Turkic languages, and later remodeled completely under Germanic influence. In our view, there are major conceptual problems with both the genetic and linguistic parts of the work. We argue that GPS is a provenancing tool suited to inferring the geographic region where a modern and recently unadmixed genome is most likely to arise, but is hardly suitable for admixed populations and for tracing ancestry up to 1,000 years before present, as its authors have previously claimed. Moreover, all methods of historical linguistics concur that Yiddish is a Germanic language, with no reliable evidence for Slavic, Iranian, or Turkic substrata. PMID:27389685

  16. Life-history strategies constrain invertebrate community tolerance to multiple stressors: A case study in the Ebro basin.

    PubMed

    Mondy, Cédric P; Muñoz, Isabel; Dolédec, Sylvain

    2016-12-01

    Multiple stressors constitute a serious threat to aquatic ecosystems, particularly in the Mediterranean region where water scarcity is likely to interact with other anthropogenic stressors. Biological traits potentially allow the unravelling of the effects of multiple stressors. However, thus far, trait-based approaches have failed to fully deliver on their promise and still lack strong predictive power when multiple stressors are present. We aimed to quantify specific community tolerances against six anthropogenic stressors and investigate the responses of the underlying macroinvertebrate biological traits and their combinations. We built and calibrated boosted regression tree models to predict community tolerances using multiple biological traits with a priori hypotheses regarding their individual responses to specific stressors. We analysed the combinations of traits underlying community tolerance and the effect of trait association on this tolerance. Our results validated the following three hypotheses: (i) the community tolerance models efficiently and robustly related trait combinations to stressor intensities and, to a lesser extent, to stressors related to the presence of dams and insecticides; (ii) the effects of traits on community tolerance not only depended on trait identity but also on the trait associations emerging at the community level from the co-occurrence of different traits in species; and (iii) the community tolerances and the underlying trait combinations were specific to the different stressors. This study takes a further step towards predictive tools in community ecology that consider combinations and associations of traits as the basis of stressor tolerance. Additionally, the community tolerance concept has potential application to help stream managers in the decision process regarding management options. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  17. A historical perspective on the male sexual case history.

    PubMed

    Quallich, Susanne A

    2014-01-01

    The contemporary sexual medicine case history is grounded in the Biopsychosocial Model and its recognition that the past influences one's current interpretation of symptoms. However, the thread of this model can be found throughout the case studies of the early pioneers of sexology. These early investigators began with examinations of homosexual men, slowly moving toward awareness that male sexuality comprises a continuum, while striving to place sexual behavior in a biologic context. Their perspectives served to establish the groundwork for the emerging construct of sexuality and helped shape current methods for identification of sexual function concerns.

  18. The Energy Crisis and the Media: Some Case Histories.

    ERIC Educational Resources Information Center

    Schmertz, Herbert

    The five case histories presented in this paper discuss the relations of the Mobil Oil Corporation with various news media since 1973, particularly the difficulties that the oil industry has faced in communicating with and through the news media. The case histories deal with the following topics; news stories about tankers allegedly waiting…

  19. The Energy Crisis and the Media: Some Case Histories.

    ERIC Educational Resources Information Center

    Schmertz, Herbert

    The five case histories presented in this paper discuss the relations of the Mobil Oil Corporation with various news media since 1973, particularly the difficulties that the oil industry has faced in communicating with and through the news media. The case histories deal with the following topics; news stories about tankers allegedly waiting…

  20. Case-History and Clinical Observations: Valuable Material for Teachers.

    ERIC Educational Resources Information Center

    Morgan, Sharon R.

    1979-01-01

    Intended for teachers of severely emotionally disturbed children, the article reviews the various components of case histories and clinical observations, focusing on how to read the material and ferret out the important issues that will help in planning classroom strategies. A case history of an autistic boy is presented to illustrate the process.…

  1. Swordfish and mercury: a case history

    SciTech Connect

    Officer, C.B.; Ryther, J.H.

    1981-01-01

    On April 2, 1970, FDA set a guideline for the amount of mercury permissible in fish. The history of FDA's decision is examined, and a short history of Minamata disease named after a type of mercury poisoning originating in Minamata, Japan, is presented. The methodology used by the FDA in setting a mercury guideline is criticized, while FDA findings are refuted. (2 drawings, 1 graph, 3 photos, 6 references)

  2. Eva's stories: recognizing the poverty of the medical case history.

    PubMed

    Sobel, R J

    2000-01-01

    The medical case history is a proven tool for approaching the question "What is wrong with this person?" Its virtues, however, can become vices, in part as a consequence of the dehumanizing flight from sensitive subjectivity to sanitized objectivity, from human interest to "science." The case history, because it is so useful and effective, is not likely to be profoundly altered in the future, but medical educators can make themselves and their students more aware of the serious flaw in this form of discourse, i.e., the erasure of the unique individual from his or her disease. The exercise of asking medical students to abstract case histories from richly written short stories, novels, plays, or operas might heighten students' recognition of the poverty of the medical case history. To illustrate this idea, the story of Eva, a dying woman, is presented initially as a typical medical case history; it is then contrasted with excerpts from a novelist's narrative of Eva's life.

  3. Creating Contexts for Studying History with Students Learning English.

    ERIC Educational Resources Information Center

    Olmedo, Irma M.

    1996-01-01

    Argues for using oral history studies to develop language skills and teach social science concepts to limited-English-speaking students. Interviewing family and community members provides students with a familiar context, while translating and transcribing sharpens their language skills. Includes an oral history case study. (MJP)

  4. Teaching Global History: A Social Studies Approach

    ERIC Educational Resources Information Center

    Singer, Alan J.

    2011-01-01

    "Teaching Global History" challenges prospective and beginning social studies teachers to formulate their own views about what is important to know in global history and why. It explains how to organize the curriculum around broad social studies concepts and themes and student questions about humanity, history, and the contemporary world. All…

  5. "Publish or Perish" as citation metrics used to analyze scientific output in the humanities: International case studies in economics, geography, social sciences, philosophy, and history.

    PubMed

    Baneyx, Audrey

    2008-01-01

    Traditionally, the most commonly used source of bibliometric data is the Thomson ISI Web of Knowledge, in particular the (Social) Science Citation Index and the Journal Citation Reports, which provide the yearly Journal Impact Factors. This database used for the evaluation of researchers is not advantageous in the humanities, mainly because books, conference papers, and non-English journals, which are an important part of scientific activity, are not (well) covered. This paper presents the use of an alternative source of data, Google Scholar, and its benefits in calculating citation metrics in the humanities. Because of its broader range of data sources, the use of Google Scholar generally results in more comprehensive citation coverage in the humanities. This presentation compares and analyzes some international case studies with ISI Web of Knowledge and Google Scholar. The fields of economics, geography, social sciences, philosophy, and history are focused on to illustrate the differences of results between these two databases. To search for relevant publications in the Google Scholar database, the use of "Publish or Perish" and of CleanPoP, which the author developed to clean the results, are compared.

  6. Case-control study of male germ cell tumors nested in a cohort of car-manufacturing workers: Findings from the occupational history.

    PubMed

    Langner, Ingo; Schmeisser, Nils; Mester, Birte; Behrens, Thomas; Gottlieb, Andrea; Ahrens, Wolfgang

    2010-10-01

    To examine whether the previously observed excess risk of male germ cell cancer in a cohort of car-manufacturing workers can be attributed to occupational activities inside and/or outside the car industry. A nested case-control study among workers in six plants included 205 cases of germ cell cancer and 1,105 controls, individually matched by year of birth (±2 years). Job periods of the individual occupational histories were coded based on the International Standard Classification of Occupations (ISCO) and the industrial classification of economic activities (NACE). Odds ratios (ORs) and corresponding 95%-confidence intervals (CI) for ever-never and cumulative employment were calculated by conditional multivariate logistic regression adjusted for cryptorchidism. Significantly increased risks were observed for machinery fitters and assemblers (A) (OR = 1.8, 95% CI 1.25-2.53) and "workers not elsewhere classified" (OR = 2.10, 95% CI 1.27-3.54), but no trend was observed for employment duration in either occupational group. Stratification of job group A by metal-cutting and non-cutting jobs yielded ORs of 1.87 (95% CI 1.31-2.67) and of 1.24 (95% CI 0.68-2.28), respectively. Among "plumbers, welders, sheet & structural metal workers" (adjusted OR 1.4, 95% CI 0.99-1.95) only "structural metal preparers and erectors" showed a substantially increased risk (OR = 2.30; 95% CI 1.27-4.27). Our results do not fully explain the increased incidence of germ cell cancer in the cohort, but support previous findings showing increased risks among metal workers. These risks were most strongly pronounced in metal-cutting activities. © 2010 Wiley-Liss, Inc.

  7. History on Trial: The Case of Columbus.

    ERIC Educational Resources Information Center

    Como, Robert M.; O' Connor, John S.

    1998-01-01

    Describes the experiences of one high school class as they attempted to sort out the conflicting representations of Christopher Columbus. The students examined several textbooks and other histories. They then conducted a mock trial to determine if Columbus should be considered a criminal, a hero, or both. (MJP)

  8. Case Histories of Landslide Impact: A Database-driven Approach

    NASA Astrophysics Data System (ADS)

    Klose, Martin; Damm, Bodo

    2015-04-01

    Fundamental understanding of landslide risk requires in-depth knowledge of how landslides have impacted society in the past (e.g., Corominas et al., 2014). A key to obtain insights into the evolution of landslide risk at single facilities of critical infrastructures are case histories of landslide impact. The purpose of such historical analyses is to inform about the site-specific interactions between landslides and land-use activity. Case histories support correlating landslide events and associated damages with multiple control variables of landslide risk, including (i) previous construction works, (ii) hazard awareness, (iii) the type of structure or its material properties, and (iv) measures of post-disaster mitigation. It is a key advantage of case histories to provide an overview of the changes in the exposure and vulnerability of infrastructures over time. Their application helps to learn more about changing patterns in risk culture and the effectiveness of repair or prevention measures (e.g., Klose et al., 2014). Case histories of landslide impact are developed on the basis of information extracted from landslide databases. The use of path diagrams and illustrated flowcharts as data modeling techniques is aimed at structuring, condensing, and visualizing complex historical data sets on landslide activity and land-use. Much of the scientific potential of case histories simply depends on the quality of available database information. Landslide databases relying on a bottom-up approach characterized by targeted local data specification are optimally suited for historical impact analyses. Combined with systematic retrieval, extraction, and integration of data from multiple sources, landslide databases constitute a valuable tool for developing case histories that enable to open a whole new window on the study of landslide impacts (e.g., Damm and Klose, 2014). The present contribution introduces such a case history for a well-known landslide site at a heavily

  9. The use of instant medical history in a rural clinic. Case study of the use of computers in an Arkansas physician's office.

    PubMed

    Pierce, B

    2000-05-01

    This study evaluated the acceptance of using computers to take a medical history by rural Arkansas patients. Sex, age, race, education, previous computer experience and owning a computer were used as variables. Patients were asked a series of questions to rate their comfort level with using a computer to take their medical history. Comfort ratings ranged from 30 to 45, with a mean of 36.8 (SEM = 0.67). Neither sex, race, age, education, owning a personal computer, nor prior computer experience had a significant effect on the comfort rating. This study helps alleviate one of the concerns--patient acceptance--about the increasing use of computers in practicing medicine.

  10. USE OF CASE HISTORIES IN THE DEVELOPMENT OF STUDENT UNDERSTANDING OF SCIENCE AND SCIENTISTS.

    ERIC Educational Resources Information Center

    COOLEY, WILLIAM W.; KLOPFER, LEOPOLD E.

    THE USE OF CASES DRAWN FROM THE HISTORY OF SCIENCE WAS EVALUATED AS AN INSTRUCTIONAL PROCEDURE USING 108 SECONDARY SCHOOL CLASSES IN BIOLOGY, CHEMISTRY, AND PHYSICS LOCATED IN WIDELY DISTRIBUTED GEOGRAPHICAL AREAS. THE PURPOSE OF THE STUDY WAS TO DETERMINE THE EFFECTIVENESS OF THE HISTORY OF SCIENCE CASES INSTRUCTION METHOD (HOSC) IN CHANGING…

  11. ANALYSIS OF CASE HISTORIES OF PERSONAL INDEX USE.

    ERIC Educational Resources Information Center

    JAHODA, G.; AND OTHERS

    CASE HISTORIES ARE SUMMARIZED FOR 12 RESEARCHERS IN SCIENCE AND ENGINEERING AT THE FLORIDA STATE UNIVERSITY, I.E., 6 CHEMISTS, 4 BIOLOGISTS, 1 ENGINEER, AND 1 METEOROLOGIST. OVER A 10-MONTH PERIOD, 258 HISTORIES WERE OBTAINED. THE DATA DO NOT PERMIT THE DETERMINATION WITH CERTAINTY THE TYPE OF SUBJECT INDEX MOST SUITABLE FOR A PARTICULAR TYPE OF…

  12. ANALYSIS OF CASE HISTORIES OF PERSONAL INDEX USE.

    ERIC Educational Resources Information Center

    JAHODA, G.; AND OTHERS

    CASE HISTORIES ARE SUMMARIZED FOR 12 RESEARCHERS IN SCIENCE AND ENGINEERING AT THE FLORIDA STATE UNIVERSITY, I.E., 6 CHEMISTS, 4 BIOLOGISTS, 1 ENGINEER, AND 1 METEOROLOGIST. OVER A 10-MONTH PERIOD, 258 HISTORIES WERE OBTAINED. THE DATA DO NOT PERMIT THE DETERMINATION WITH CERTAINTY THE TYPE OF SUBJECT INDEX MOST SUITABLE FOR A PARTICULAR TYPE OF…

  13. The Changing Role of the Academic Journal: The Coverage of Higher Education in "History of Education" as a Case Study, 1972-2011

    ERIC Educational Resources Information Center

    Lowe, Roy

    2012-01-01

    This article briefly reviews the coverage of higher education in the pages of this journal since its inception. It reflects on the changing role of the academic journal during this period, on some of the related changes which have taken place in academia itself as well as changing fashions in the study of history of education. Its central…

  14. Art History, Art Criticism, and Art Production. An Examination of Art Education in Selected School Districts. Volume II: Case Studies of Seven Selected Sites.

    ERIC Educational Resources Information Center

    Day, Michael; And Others

    This report covers the findings from a cross-site analysis of seven sites that were implementing a discipline-based approach to visual arts education. A discipline-based approach incorporates four art disciplines in the classroom: art history, art criticism, aesthetics, and art making. The study focused on two major areas: (1) factors generating…

  15. The Changing Role of the Academic Journal: The Coverage of Higher Education in "History of Education" as a Case Study, 1972-2011

    ERIC Educational Resources Information Center

    Lowe, Roy

    2012-01-01

    This article briefly reviews the coverage of higher education in the pages of this journal since its inception. It reflects on the changing role of the academic journal during this period, on some of the related changes which have taken place in academia itself as well as changing fashions in the study of history of education. Its central…

  16. Facilitation of Prosthetic Rehabilitation in Scleroderma: Case History Report.

    PubMed

    Mostafavi, Azam S; Hajimahmoudi, Mohammadreza

    Dental management of scleroderma patients is difficult and complicated because of compromised intraoral access. Physiotherapy may play an adjunctive and effective treatment role as described in a follow-up report on a previously documented case history.

  17. Risk of breast cancer and family history of other cancers in first-degree relatives in Chinese women: a case control study.

    PubMed

    Zhou, Wenbin; Ding, Qiang; Pan, Hong; Wu, Naping; Liang, Mengdi; Huang, Yaoyu; Chen, Lin; Zha, Xiaoming; Liu, Xiaoan; Wang, Shui

    2014-09-11

    Few studies have systematically reported the relationship between the risk of breast cancer and family history of other cancers. This study was designed to systematically determine the relationship between breast cancer risk and family history of other cancers in first-degree relatives. Between January 2006 and June 2011, 823 women diagnosed with breast cancer were included, and age-matched women diagnosed with benign breast disease were selected as controls. Family history of other cancers in first-degree relatives was recorded by trained reviewers. Multivariate logistic regression was applied to analyze the relationships. A family history of esophagus cancer (OR: 2.70, 95% CI: 1.11 - 6.57), lung cancer (OR: 2.49 95% CI: 1.10 - 5.65), digestive system cancer (OR: 1.79, 95% CI: 1.14 - 2.79) and any cancer (OR: 2.13, 95% CI: 1.49 - 3.04) in first-degree relatives was directly associated with increased breast cancer risk. In subgroup analysis, the risk of hormone receptor positive breast cancer was increased in subjects with a family history of lung cancer (OR: 3.37, 95% CI: 1.45 - 7.82), while the risk of hormone receptor negative breast cancer was increased in subjects with a family history of esophagus cancer (OR: 6.19, 95% CI: 2.30 - 16.71), uterus cancer (OR: 6.92, 95% CI: 1.12 - 42.89), digestive tract cancer (OR: 2.05, 95% CI: 1.03 - 4.10) and gynecology cancer (OR: 6.79, 95% CI: 1.46 - 31.65). Additionally, a significant increase in breast cancer was observed with a family history of digestive system cancer for subjects 50 y and younger (OR: 1.88, 95% CI: 1.03 - 3.43), not for subjects 50 y older (OR: 1.67, 95% CI: 0.86 - 3.25). Breast cancer aggregates in families with several types of cancer especially for digestive system cancer. The influence of a family history of other cancers seems more likely to be limited to hormone receptor negative breast cancer.

  18. [Talcosis as an occupational disease. Case histories].

    PubMed

    Avolio, G; Galietti, F; Oliaro, A; Iorio, M; Cacciabue, M

    1989-03-01

    The case are examined of 49 people (45 males, 4 females), mean age 60 exposed to the risk of talc inhalation in a talc processing and packing factory who were granted disability pensions by the Turin I.N.A.I.L. on the grounds of silicosis in 1975-86. Radiologically the cases presented small round patches in 28 subjects small irregular ones in 15 and large patches in 6. In functional terms, examination revealed ventilatory insufficiency that was primarily restrictive in 17 cases, obstructive in 11 and mixed in 21.

  19. Life histories, salinity zones, and sublethal contributions of contaminants to pelagic fish declines illustrated with a case study of San Francisco Estuary, California, USA

    USGS Publications Warehouse

    Brooks, Marjorie L.; Fleishman, Erica; Brown, Larry R.; Lehman, Peggy W.; Werner, Inge; Scholz, Nathaniel; Michelmore, Carys; Loworn, James R.; Johnson, Michael L.; Schlenk, Daniel

    2012-01-01

    Human effects on estuaries are often associated with major decreases in abundance of aquatic species. However, remediation priorities are difficult to identify when declines result from multiple stressors with interacting sublethal effects. The San Francisco Estuary offers a useful case study of the potential role of contaminants in declines of organisms because the waters of its delta chronically violate legal water quality standards; however, direct effects of contaminants on fish species are rarely observed. Lack of direct lethality in the field has prevented consensus that contaminants may be one of the major drivers of coincident but unexplained declines of fishes with differing life histories and habitats (anadromous, brackish, and freshwater). Our review of available evidence indicates that examining the effects of contaminants and other stressors on specific life stages in different seasons and salinity zones of the estuary is critical to identifying how several interacting stressors could contribute to a general syndrome of declines. Moreover, warming water temperatures of the magnitude projected by climate models increase metabolic rates of ectotherms, and can hasten elimination of some contaminants. However, for other pollutants, concurrent increases in respiratory rate or food intake result in higher doses per unit time without changes in the contaminant concentrations in the water. Food limitation and energetic costs of osmoregulating under altered salinities further limit the amount of energy available to fish; this energy must be redirected from growth and reproduction toward pollutant avoidance, enzymatic detoxification, or elimination. Because all of these processes require energy, bioenergetics methods are promising for evaluating effects of sublethal contaminants in the presence of other stressors, and for informing remediation. Predictive models that evaluate the direct and indirect effects of contaminants will be possible when data become

  20. Life-history trait plasticity and its relationships with plant adaptation and insect fitness: a case study on the aphid Sitobion avenae

    PubMed Central

    Dai, Peng; Shi, Xiaoqin; Liu, Deguang; Ge, Zhaohong; Wang, Da; Dai, Xinjia; Yi, Zhihao; Meng, Xiuxiang

    2016-01-01

    Phenotypic plasticity has recently been considered a powerful means of adaptation, but its relationships with corresponding life-history characters and plant specialization levels of insects have been controversial. To address the issues, Sitobion avenae clones from three plants in two areas were compared. Varying amounts of life-history trait plasticity were found among S. avenae clones on barley, oat and wheat. In most cases, developmental durations and their corresponding plasticities were found to be independent, and fecundities and their plasticities were correlated characters instead. The developmental time of first instar nymphs for oat and wheat clones, but not for barley clones, was found to be independent from its plasticity, showing environment-specific effects. All correlations between environments were found to be positive, which could contribute to low plasticity in S. avenae. Negative correlations between trait plasticities and fitness of test clones suggest that lower plasticity could have higher adaptive value. Correlations between plasticity and specialization indices were identified for all clones, suggesting that plasticity might evolve as a by-product of adaptation to certain environments. The divergence patterns of life-history plasticities in S. avenae, as well as the relationships among plasticity, specialization and fitness, could have significant implications for evolutionary ecology of this aphid. PMID:27426961

  1. Trypanosoma cruzi in non-human primates with a history of stillbirths: a retrospective study (Papio hamadryas spp.) and case report (Macaca fascicularis)

    PubMed Central

    Grieves, Jessica L.; Hubbard, Gene B.; Williams, Jeff T.; VandeBerg, John L.; Dick, Edward J.; López-Alvarenga, Juan C.; Schlabritz-Loutsevitch, Natalia E.

    2011-01-01

    Background Congenital transmission of Trypanosoma cruzi has been described in humans and experimental work has been conducted with mice, but not with non-human primates (NHPs). Methods We conducted a retrospective study of female baboons (Papio hamadryas spp.) naturally seropositive or seronegative for T. cruzi with history of fetal loss, and we report a stillbirth in a cynomolgus macaque (Macaca fascicularis) with placental T. cruzi amastigotes. Results There were no differences in menstrual cycle parameters and the number of fetal losses between seropositive and seronegative baboons with history of fetal loss. The amount of parasite DNA detected using quantitative polymerase chain reaction (Q-PCR) in M. fascicularis placenta was within the range detected in infected baboon tissues. Conclusions There is no evidence that chronic maternal T. cruzi infection causes fetal loss in baboons. Q-PCR is a useful diagnostic tool to study archived NHP placentas. PMID:18671769

  2. Instructional Computing: Ten Case Studies.

    ERIC Educational Resources Information Center

    Hargan, Carol; Hunter, Beverly

    These case studies are written for educational institutions that wish to plan, extend, or improve their use of computers for learning and teaching. Each case study includes a brief description of each of the following: profile of the institution, history of the development of instructional computing, organization and management, student access to…

  3. Kabbalah: On Spatio-Temporal Database Visualization With Historical Events: A Case Study of History Flow of Chia-Yi Beimen Station

    NASA Astrophysics Data System (ADS)

    Hsu, T. W.; Chiou, S. C.; Lee, J. H.

    2015-08-01

    This system is made for researchers who study pattern of city or spatial transformation by using computational way to interpret data logically. In order to make use of all historical data with GIS in system, an exact metadata is necessary and needed to build first. The Cubism project is aimed to presume how different historical data normalized to become information in spatio-temporal database. To make temporal map have higher capability with presentation of history context.

  4. The sirenomelia sequence: a case history.

    PubMed

    Fadhlaoui, Anis; Khrouf, Mohamed; Gaigi, Soumaya; Zhioua, Fethi; Chaker, Anis

    2010-01-01

    We report a case of sirenomelia sequence observed in an incident of preterm labor during the 29th gestational week. According to some authors, this syndrome should be classified separately from caudal regression syndrome and is likely to be the result of an abnormality taking place during the fourth gestational week, causing developmental abnormalities in the lower extremities, pelvis, genitalia, urinary tract and digestive organs. Despite recent progress in pathology, the etiopathogenesis of sirenomelia is still debated.

  5. Active strike-slip faulting history inferred from offsets of topographic features and basement rocks: a case study of the Arima Takatsuki Tectonic Line, southwest Japan

    NASA Astrophysics Data System (ADS)

    Maruyama, Tadashi; Lin, Aiming

    2002-01-01

    Geological, geomorphological and geophysical data have been used to determine the total displacement, slip rates and age of formation of the Arima-Takatsuki Tectonic Line (ATTL) in southwest Japan. The ATTL is an ENE-WSW-trending dextral strike-slip fault zone that extends for about 60 km from northwest of the Rokko Mountains to southwest of the Kyoto Basin. The ATTL marks a distinct topographic boundary between mountainous regions and basin regions. Tectonic landforms typically associated with active strike-slip faults, such as systematically-deflected stream channels, offset ridges and fault scarps, are recognized along the ATTL. The Quaternary drainage system shows progressive displacement along the fault traces: the greater the magnitude of stream channel, the larger the amount of offset. The maximum dextral deflection of stream channels is 600-700 m. The field data and detailed topographic analyses, however, show that pre-Neogene basement rocks on both sides of the ATTL are displaced by about 16-18 km dextrally and pre-Mio-Pliocene elevated peneplains are also offset 16-17 km in dextral along the ATTL. This suggests that the ATTL formed in the period between the development of the pre-Mio-Pliocene peneplains and deflection of the Quaternary stream channels. The geological, geomorphological and geophysical evidence presented in this study indicates that (1) the ATTL formed after the mid-Miocene, (2) the ATTL has moved as a dextral strike-slip fault with minor vertical component since its formation to late Holocene and (3) the ATTL is presently active with dextral slip rates of 1-3 mm/year and a vertical component of >0.3 mm/year. The formation of the ATTL was probably related to the opening of the Japan Sea, which is the dominant tectonic event around Japan since mid-Miocene. The case study of the ATTL provides insight into understanding the tectonic history and relationship between tectonic landforms and structures in active strike-slip faults.

  6. Syn-orogenic extensional pulses within the contractional history of thrust wedges. The Val di Lima low-angle normal fault case study, Northern Apennines, Italy.

    NASA Astrophysics Data System (ADS)

    Clemenzi, Luca; Molli, Giancarlo; Storti, Fabrizio; Muchez, Philippe; Swennen, Rudy; Torelli, Luigi

    2014-05-01

    overpressures locally influenced active deformation processes and favored shear localization. We propose that the folded low-angle extensional fault system indicates the occurrence of an extensional pulse that affected this sector of the thrust wedge during the orogenic contractional history. In particular, the fault system is considered to be the flat portion of a stair-case extensional fault system developed in the shallower portion of the thrust wedge to compensate for its supercritical taper produced by uplift of the internal zone due to deep-rooted thrusting. Important pulses of wedge extension, similar to the one described here, are likely to occur during the geological history of most thrust wedges, because their long-term evolution is characterized by complex interactions among tectonics, gravitational body forces, and (sub)surface processes. The systems of brittle extensional fault zones, resulting from such extensional pulses, affect fluid circulation through the upper crust by producing articulated networks of hydraulic conduits, barriers, or mixed conduit-barrier systems. In particular, as demonstrated by our results, the effects of extensional fault zones on fluid circulation is twofold: i) they provide effective fluid pathways allowing deep infiltration of surface-derived marine or meteoric water; ii) they can trigger fluid overpressuring, especially in the footwall of shallow-dipping fault segments. Eventually, fluid circulation can exert a strong influence on the mechanical behavior of thrust wedges either by reducing the effective normal stress at depth or triggering the formation of hydrous clay minerals lowering the frictional properties of fault zones.

  7. [Siemens I syndrome--a case history].

    PubMed

    Köhler, U; Müller, W; Schubert, H; Lukassek, B

    1981-08-01

    Report on a patient suffering from keratosis follicularis spinulosa decalvans (Siemens I syndrome). This ia a very rare clinical picture, at least in its complete form. The patient's father and brother are suffering from an abortive Siemens I syndrome. The condition is a form of hereditary parakeratosis, a spinulose keratosis with typical localization in the eyes and on the skin. Causal therapy is not possible; attempts at conservative and surgical treatment are described. Prognostically, the condition will probably come to a standstill at puberty. The description of this case is intended to illustrate the necessity of close cooperation between dermatologist and ophthalmologist.

  8. Breast hypoplasia and breastfeeding: a case history.

    PubMed

    Thorley, Virginia

    2005-07-01

    Hypoplasia, or glandular insufficiency, of the breasts is an infrequent cause of breastfeeding failure or infant failure to thrive. Early evaluation of the breasts of early identification of infant indicators can enable mothers to breastfeed while providing appropriate supplementation to facilitate satisfactory hydration and growth. A case report is presented of a highly motivated mother with minimal breast tissue who was able to soothe four of her infants at her breasts, supplying some breastmilk, while providing the bulk of their nutritional requirements by other means. At the time of writing she is tandem breastfeeding as well as providing artificial milk by bottle.

  9. Case Study: Testing with Case Studies

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman

    2015-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses using case studies to test for knowledge or lessons learned.

  10. Case Study: Testing with Case Studies

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman

    2015-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses using case studies to test for knowledge or lessons learned.

  11. Case histories of West Valley spent fuel shipments: Final report

    SciTech Connect

    Not Available

    1987-01-01

    In 1983, NRC/FC initiated a study on institutional issues related to spent fuel shipments originating at the former spent fuel processing facility in West Valley, New York. FC staff viewed the shipment campaigns as a one-time opportunity to document the institutional issues that may arise with a substantial increase in spent fuel shipping activity. NRC subsequently contracted with the Aerospace Corporation for the West Valley Study. This report contains a detailed description of the events which took place prior to and during the spent fuel shipments. The report also contains a discussion of the shipment issues that arose, and presents general findings. Most of the institutional issues discussed in the report do not fall under NRC's transportation authority. The case histories provide a reference to agencies and other institutions that may be involved in future spent fuel shipping campaigns. 130 refs., 7 figs., 19 tabs.

  12. Characteristics of the Foot Static Alignment and the Plantar Pressure Associated with Fifth Metatarsal Stress Fracture History in Male Soccer Players: a Case-Control Study.

    PubMed

    Matsuda, Sho; Fukubayashi, Toru; Hirose, Norikazu

    2017-12-01

    There is a large amount of information regarding risk factors for fifth metatarsal stress fractures; however, there are few studies involving large numbers of subjects. This study aimed to compare the static foot alignment and distribution of foot pressure of athletes with and without a history of fifth metatarsal stress fractures. The study participants comprised 335 collegiate male soccer players. Twenty-nine with a history of fifth metatarsal stress fractures were in the fracture group and 306 were in the control group (with subgroups as follows: 30 in the fracture foot group and 28 in the non-fracture group). We measured the foot length, arch height, weight-bearing leg-heel alignment, non-weight-bearing leg-heel alignment, forefoot angle relative to the rearfoot, forefoot angle relative to the horizontal axis, and foot pressure. The non-weight-bearing leg-heel alignment was significantly smaller and the forefoot angle relative to the rearfoot was significantly greater in the fracture foot group than in the control foot group (P = 0.049 and P = 0.038, respectively). With regard to plantar pressure, there were no significant differences among the groups. Midfield players had significantly higher rates of fifth metatarsal stress fracture in their histories, whereas defenders had significantly lower rates (chi-square = 13.2, P < 0.05). There were no significant differences in the frequency of fifth metatarsal stress fractures according to the type of foot (kicking foot vs. pivoting foot) or the severity of ankle sprain. Playing the midfield position and having an everted rearfoot and inverted forefoot alignment were associated with fifth metatarsal stress fractures. This information may be helpful for preventing fifth metatarsal stress fracture recurrence. More detailed load evaluations and a prospective study are needed in the future.

  13. Case history of the Cormorant field single satellite well

    SciTech Connect

    Brommer, J.J.; Fernandinho, C.M.M.S.; Liles, J.R.

    1982-01-01

    A case history of the development of specifically tailor-made equipment and the experience gained from the installation and production from the first subsea well in the central area of the Cormorant field is presented. Emphasis is placed on development concepts and the equipment uniquely manufactured to meet special needs. A one-year onshore integrated system test of the equipment is described along with the interface problems identified and resolved prior to going offshore. Actual installation and commissioning activities are fully covered including drilling, completion, and production from the well. The study describes the major reasons for the success of the subsea well to date as being extensive onshore testing, detailed planning, and the early involvement of operating personnel.

  14. Educational Research--History of Education a Curious Case?

    ERIC Educational Resources Information Center

    Goodman, Joyce; Grosvenor, Ian

    2009-01-01

    The article begins with an exploration of the current state of history of education by drawing on published reviews of history of education, thematic analysis of journal content, and mapping of postgraduate study. It then highlights "moments of insecurity". These are characterised by a particular discourse that frames the future of the discipline…

  15. Educational Research--History of Education a Curious Case?

    ERIC Educational Resources Information Center

    Goodman, Joyce; Grosvenor, Ian

    2009-01-01

    The article begins with an exploration of the current state of history of education by drawing on published reviews of history of education, thematic analysis of journal content, and mapping of postgraduate study. It then highlights "moments of insecurity". These are characterised by a particular discourse that frames the future of the discipline…

  16. Making the Case for History in Medical Education.

    PubMed

    Jones, David S; Greene, Jeremy A; Duffin, Jacalyn; Harley Warner, John

    2015-10-01

    Historians of medicine have struggled for centuries to make the case for history in medical education. They have developed many arguments about the value of historical perspective, but their efforts have faced persistent obstacles, from limited resources to curricular time constraints and skepticism about whether history actually is essential for physicians. Recent proposals have suggested that history should ally itself with the other medical humanities and make the case that together they can foster medical professionalism. We articulate a different approach and make the case for history as an essential component of medical knowledge, reasoning, and practice. History offers essential insights about the causes of disease (e.g., the non-reductionistic mechanisms needed to account for changes in the burden of disease over time), the nature of efficacy (e.g., why doctors think that their treatments work, and how have their assessments changed over time), and the contingency of medical knowledge and practice amid the social, economic, and political contexts of medicine. These are all things that physicians must know in order to be effective diagnosticians and caregivers, just as they must learn anatomy or pathophysiology. The specific arguments we make can be fit, as needed, into the prevailing language of competencies in medical education.

  17. Post-LGM Depositional History using High-Resolution Seismic Stratigraphy and Remote Acoustic Properties: A Case Study from Lake Windermere, UK

    NASA Astrophysics Data System (ADS)

    Pinson, L.; Vardy, M. E.; Dix, J. K.; Henstock, T.; Bull, J. M.

    2009-12-01

    structures in the region, and so it has been previously suggested that rapid climate amelioration at the end of the LGM caused the glaciers to down-waste in situ. A range of retreat moraines identified within this study indicate active-ice removal from the lake throughout the BIIS retreat phase, further their locations and morphology provide insights into the patterns and processes of a more complex deglacial history. The lake also provides a high resolution record of the immediate de-glacial sedimentary environment, the Younger Dryas fluvio-glacial impacts and terrestrial and lacustrine slope failures, and the climatic amelioration associated with the Holocene.

  18. The history of the case report: a selective review

    PubMed Central

    Nissen, Trygve

    2014-01-01

    The clinical case report is a popular genre in medical writing. While authors and editors have debated the justification for the clinical case report, few have attempted to examine the long history of this genre in medical literature. By reviewing selected literature and presenting and discussing excerpts of clinical case reports from Egyptian antiquity to the 20th century, we illustrate the presence of the genre in medical science and how its form developed. Central features of the clinical case report in different time periods are discussed, including its main components, structure, style and author presence. PMID:25057387

  19. A case revealing the natural history of untreated Lyme disease.

    PubMed

    Schoen, Robert T

    2011-03-01

    A 71-year-old woman presented to a rheumatologist with what she believed to be a 2-year history of Lyme disease, progressing from erythema migrans to Lyme arthritis. History, physical examination and serologic testing confirmed the diagnosis of Lyme disease. Lyme disease. The patient refused antibiotic therapy during the first 2 years of her illness. During the next 2 years, she consulted a rheumatologist, but declined antibiotic therapy. She continued to have recurrent episodes of arthritis, following which she was successfully treated with doxycycline, given initially for 2 weeks, with a second, 4-week cycle administered 2 months later. This case illustrates the natural history of untreated Lyme disease, which is rarely observed in most patients since diagnosis almost always leads to successful antibiotic treatment. Furthermore, this case also demonstrates that infection with Borrelia burgdorferi can persist for years in untreated patients; however, antibiotic therapy is still likely to be effective, despite long-term infection.

  20. Opon Gas Field, Colombia: Part II - drilling case history

    SciTech Connect

    Greener, J.M.; Trimble, G.E.; Singer, G.M.; Barnes, M.J.

    1996-12-31

    This paper describes the Opon Gas Field development drilling case history in the Middle Magdalena Basin of north-central Colombia, South America. World class levels of drilling fluid and cementing densities in excess of 22.0 ppg were required to control the extreme pressures encountered. A continuous improvement process is detailed in regard to casing, drilling fluid, cement and related drilling mechanics programs in a severely pressured and environmentally sensitive operation.

  1. Using Case Histories in Health Sciences Education- An Example: Leukemia

    ERIC Educational Resources Information Center

    Karni, Karen; And Others

    1976-01-01

    To provide an example of how case histories have been developed and used as one means to a team approach to health care in the course, "The Patient and Health Care Team," this paper describes one topic--leukemia--to show the interaction of health care professionals, as well as input from the family itself. (HD)

  2. Using Case Histories in Health Sciences Education- An Example: Leukemia

    ERIC Educational Resources Information Center

    Karni, Karen; And Others

    1976-01-01

    To provide an example of how case histories have been developed and used as one means to a team approach to health care in the course, "The Patient and Health Care Team," this paper describes one topic--leukemia--to show the interaction of health care professionals, as well as input from the family itself. (HD)

  3. Case history advanced coatings for water treatment plant components

    SciTech Connect

    Stephenson, L.D.; Kumar, A.

    2008-12-15

    Components of water treatment plants (WTPs) are susceptible to corrosion from constant immersion in water. A case history of corrosion and proximity to chlorine problems and their treatment at an Army WTP is presented. Solutions included using high micro-silica restoration mortar and advanced coal tar epoxy coatings.

  4. Cooperative Learning about Nature of Science with a Case from the History of Science

    ERIC Educational Resources Information Center

    Wolfensberger, Balz; Canella, Claudia

    2015-01-01

    This paper reports a predominantly qualitative classroom study on cooperative learning about nature of science (NOS) using a case from the history of science. The purpose of the research was to gain insight into how students worked with the historical case study during cooperative group work, how students and teachers assessed the teaching unit,…

  5. A Case-Study of One Teacher's Use of an Interactive Whiteboard System to Support Knowledge Co-Construction in the History Classroom

    ERIC Educational Resources Information Center

    Deaney, Rosemary; Chapman, Arthur; Hennessy, Sara

    2009-01-01

    Interactive whiteboards (IWBs) have rapidly become an integral feature of many classrooms across the UK and elsewhere, but debate continues regarding the pedagogical implications of their use. This article reports on an in-depth case-study from the wider T-MEDIA project (Teacher Mediation of Subject Learning with ICT: a Multimedia Approach). A key…

  6. A Case-Study of One Teacher's Use of an Interactive Whiteboard System to Support Knowledge Co-Construction in the History Classroom

    ERIC Educational Resources Information Center

    Deaney, Rosemary; Chapman, Arthur; Hennessy, Sara

    2009-01-01

    Interactive whiteboards (IWBs) have rapidly become an integral feature of many classrooms across the UK and elsewhere, but debate continues regarding the pedagogical implications of their use. This article reports on an in-depth case-study from the wider T-MEDIA project (Teacher Mediation of Subject Learning with ICT: a Multimedia Approach). A key…

  7. Environmental History: A New Challenge for the Social Studies

    ERIC Educational Resources Information Center

    Purmont, Jon E.

    1976-01-01

    Through the use of case studies, the classroom teacher can integrate environmental history into the social studies course, emphasizing the historical nature of environmental problems. Students can then apply the resulting knowledge, sensitivity, and awareness to developing attitudes and strengthening concerns for present and future ecological…

  8. The Treatment of Recent U.S. History in Elementary School Social Studies Textbooks: A Case Study of the Breadth and Depth of Content Coverage.

    ERIC Educational Resources Information Center

    Woodward, Arthur

    The paper analyzes seven widely-used fifth grade social studies textbooks with the hypothesis that texts are unnecessarily loaded with poorly conceived instructional design features that often do not relate to content or skills and tend to minimize the primary function of the texts. Using present and future challenges facing the United States as a…

  9. Social Studies: Is It History?

    ERIC Educational Resources Information Center

    Zamosky, Lisa

    2008-01-01

    It is year six of the No Child Left Behind (NCLB) law, and, according to this author, social studies has suffered greatly. In spite of the public outcry over the law's testing mandates and limited federal funding, some educators believe most of the public does not know about core academic subjects being squeezed out of the K-12 public school…

  10. History of Pay Equity Studies.

    ERIC Educational Resources Information Center

    Barbezat, Debra A.

    2002-01-01

    Traces the evolution of salary-equity studies over time, and how the findings have changed with regard to pay differences by gender and race/ethnicity. Reviews the literature on salary equity for both faculty and nonfaculty academic employees. (EV)

  11. Can we continue to neglect genomic variation in introgression rates when inferring the history of speciation? A case study in a Mytilus hybrid zone.

    PubMed

    Roux, C; Fraïsse, C; Castric, V; Vekemans, X; Pogson, G H; Bierne, N

    2014-08-01

    The use of molecular data to reconstruct the history of divergence and gene flow between populations of closely related taxa represents a challenging problem. It has been proposed that the long-standing debate about the geography of speciation can be resolved by comparing the likelihoods of a model of isolation with migration and a model of secondary contact. However, data are commonly only fit to a model of isolation with migration and rarely tested against the secondary contact alternative. Furthermore, most demographic inference methods have neglected variation in introgression rates and assume that the gene flow parameter (Nm) is similar among loci. Here, we show that neglecting this source of variation can give misleading results. We analysed DNA sequences sampled from populations of the marine mussels, Mytilus edulis and M. galloprovincialis, across a well-studied mosaic hybrid zone in Europe and evaluated various scenarios of speciation, with or without variation in introgression rates, using an Approximate Bayesian Computation (ABC) approach. Models with heterogeneous gene flow across loci always outperformed models assuming equal migration rates irrespective of the history of gene flow being considered. By incorporating this heterogeneity, the best-supported scenario was a long period of allopatric isolation during the first three-quarters of the time since divergence followed by secondary contact and introgression during the last quarter. By contrast, constraining migration to be homogeneous failed to discriminate among any of the different models of gene flow tested. Our simulations thus provide statistical support for the secondary contact scenario in the European Mytilus hybrid zone that the standard coalescent approach failed to confirm. Our results demonstrate that genomic variation in introgression rates can have profound impacts on the biological conclusions drawn from inference methods and needs to be incorporated in future studies.

  12. Socio-Demographic, Clinical and Behavioral Characteristics Associated with a History of Suicide Attempts among Psychiatric Outpatients: A Case Control Study in a Northern Mexican City

    PubMed Central

    Alvarado-Esquivel, Cosme; Sánchez-Anguiano, Luis Francisco; Arnaud-Gil, Carlos Alberto; Hernández-Tinoco, Jesús; Molina-Espinoza, Luis Fernando; Rábago-Sánchez, Elizabeth

    2014-01-01

    Background: Little is known about the epidemiology of suicide attempts among psychiatric outpatients in Mexico. This study was aimed to determine the socio-demographic, clinical and behavioral characteristics associated with suicide attempts in psychiatric outpatients in two public hospitals in Durango, Mexico. Methods: Two hundred seventy six psychiatric outpatients (154 suicide attempters and 122 patients without suicide attempt history) attended the two public hospitals in Durango City, Mexico were included in this study. Socio-demographic, clinical and behavioral characteristics were obtained retrospectively from all outpatients and compared in relation to the presence or absence of suicide attempt history. Results: Increased prevalence of suicide attempts was associated with mental and behavioral disorders due to psychoactive substance use (F10-19) (P=0.01), schizophrenia, schizotypal and delusional disorders (F20-29) (P=0.02), mood (affective) disorders (F30-39) (P<0.001), and disorders of adult personality and behavior (F60-69) (P<0.001). Multivariate analysis showed that suicide attempts were associated with young age (OR=1.21, 95% CI: 1.06-1.39; P=0.003), female gender (OR=2.98, 95% CI: 1.55-5.73; P=0.001), urban residence (OR=2.31, 95% CI: 1.17-4.57; P=0.01), memory impairment (OR=1.91, 95% CI: 1.07-3.40; P=0.02), alcohol consumption (OR=2.39, 95% CI: 1.21-4.70; P=0.01), and sexual promiscuity (OR=3.90, 95% CI: 1.74-8.77; P<0.001). Conclusions: We report the association of suicide attempts with socio-demographic, clinical and behavioral characteristics in psychiatric outpatients in Mexico. Results may be useful for an optimal planning of preventive measures against suicide attempts in psychiatric outpatients. PMID:24711751

  13. Using History to Teach Mathematics: The Case of Logarithms

    NASA Astrophysics Data System (ADS)

    Panagiotou, Evangelos N.

    2011-01-01

    Many authors have discussed the question why we should use the history of mathematics to mathematics education. For example, Fauvel (For Learn Math, 11(2): 3-6, 1991) mentions at least fifteen arguments for applying the history of mathematics in teaching and learning mathematics. Knowing how to introduce history into mathematics lessons is a more difficult step. We found, however, that only a limited number of articles contain instructions on how to use the material, as opposed to numerous general articles suggesting the use of the history of mathematics as a didactical tool. The present article focuses on converting the history of logarithms into material appropriate for teaching students of 11th grade, without any knowledge of calculus. History uncovers that logarithms were invented prior of the exponential function and shows that the logarithms are not an arbitrary product, as is the case when we leap straight in the definition given in all modern textbooks, but they are a response to a problem. We describe step by step the historical evolution of the concept, in a way appropriate for use in class, until the definition of the logarithm as area under the hyperbola. Next, we present the formal development of the theory and define the exponential function. The teaching sequence has been successfully undertaken in two high school classrooms.

  14. Steam turbine high-pressure casing repair-case history

    SciTech Connect

    Mazur, Z.; Kubiak, J.

    1996-11-01

    Many utility units approach 30 to 40 years of operating life. According to recent operation practice the units will be operated far beyond their 35-year economic life and are more likely to be used for cyclic duty. These two factors contribute to an increased potential for turbine casing problems in these units. The 158 MW steam turbine high pressure inner casing presented nozzle port bridge cracking and erosion. The cracks were caused by low cycle fatigue (LCF) due to thermal stress during rapid starting and loading. These stresses were relieved by axially slotting the bridges and fitting a dowel to seal the slot, but despite that the cracks occurred in the corners of the bridge slots and propagated very deeply into the nozzle ports. The casing material was Cr-Mo-V low alloyed steel. The dowels sealing the slots were removed partially or totally by erosion. Development of the in-situ crack repair welding technology and slot/hole machining methods are fully described. The cracks were removed and prepared for welding. The welding method was shielded metal arc welding process (SMAW), using buttering and two temperature-bead technique (two layer refinement technique). Also the peening of all the layers were carried out to reduce casing distortion. Special portable drilling and cutting heads were developed to machine the slots and holes for the dowels after welding. The slot retrofit was carried out to reduce the thermal stress concentration during start-up and load changes. The casing was put back into service after repair and nozzle block assembly.

  15. Traumatic spondylolysis in a heptathlete: a case history and review

    PubMed Central

    Castlereagh, Fleur; Pollard, Henry

    2005-01-01

    Abstract Objective To summarize the literature on stress fractures amongst athletes and to present an unusual case of an L2 stress fracture in a heptathlete who was successfully treated initially with chiropractic care and then aggravated by it. Clinical Features An elite heptathlete was diagnosed with bilateral pars interarticularis stress fractures of the L2 vertebrae. She initially presented for chiropractic treatment with unremitting low back pain. This followed previous successful treatment for back pain. After a series of unsuccessful treatments a second opinion (chiropractor) was sought. After a thorough history and examination, a series of radiographs were performed. Single photon emission computed tomography (SPECT) imaging confirmed the presence of bilateral spondylolysis at L2. Intervention and Outcome The patient began a graduated return to function that was initially based in rest and avoidance of all extension and rotational movement of the lumbar spine. Management gradually returned the patient to general activity followed by more progressive and sport specific activity after the fracture had sufficient time to heal. Conclusions This case highlights the importance of considering the type of pain, its location, the mechanism of injury, imaging studies and the result of the treatment in the short and medium term in establishing an accurate diagnosis of stress fracture of the pars interarticularis. PMID:19674651

  16. "The Sacred Spark of Wonder": Local Museums, Australian Curriculum History, and Pre-Service Primary Teacher Education: A Tasmanian Case Study

    ERIC Educational Resources Information Center

    Brett, Peter

    2014-01-01

    This article explores the intersections between museum learning in a distinctive Tasmanian setting, the possibilities of a new national History curriculum, and the evolving views and professional practices of pre-service primary teachers at one Australian university. Following a brief overview of the framework for local and Australian history that…

  17. "No Longer from Pyramids to the Empire State Building": Why Both Western Civilization and World Civilization Should Be Part of the History Major--A Case Study

    ERIC Educational Resources Information Center

    Voeltz, Richard A.

    2010-01-01

    In 2005, Peter Stearns wrote, "The ongoing debate between partisans of Western civilization surveys and fans of world history continues with no signs of any abatement." No one can deny that the rise of world history has been a phenomenon in American higher education over the past 30 years. Most high school students now take some version…

  18. CASE STUDY CRITIQUE; UPPER CLINCH CASE STUDY

    EPA Science Inventory

    Case study critique: Upper Clinch case study (from Research on Methods for Integrating Ecological Economics and Ecological Risk Assessment: A Trade-off Weighted Index Approach to Integrating Economics and Ecological Risk Assessment). This critique answers the questions: 1) does ...

  19. The case for researching the history of community nursing practice.

    PubMed

    Whitehead, D

    2001-05-01

    Despite a flurry of interest in the 1980s, the adoption of a positivist, objective, scientific paradigm for nursing research has led to a rejection of the study of nursing history as a valid pursuit in recent years. In this article, it is argued that this is a precarious situation. By not examining the history of the profession, nursing -- and in particular community nursing -- undermines its efforts to validate itself within the wider health-care arena. Nursing must learn from the mistakes of the past, as well as the successes, but do so in a critical way that does not romanticize its history.

  20. A case study of a precision fertilizer application task generation for wheat based on classified hyperspectral data from UAV combined with farm history data

    NASA Astrophysics Data System (ADS)

    Kaivosoja, Jere; Pesonen, Liisa; Kleemola, Jouko; Pölönen, Ilkka; Salo, Heikki; Honkavaara, Eija; Saari, Heikki; Mäkynen, Jussi; Rajala, Ari

    2013-10-01

    Different remote sensing methods for detecting variations in agricultural fields have been studied in last two decades. There are already existing systems for planning and applying e.g. nitrogen fertilizers to the cereal crop fields. However, there are disadvantages such as high costs, adaptability, reliability, resolution aspects and final products dissemination. With an unmanned aerial vehicle (UAV) based airborne methods, data collection can be performed cost-efficiently with desired spatial and temporal resolutions, below clouds and under diverse weather conditions. A new Fabry-Perot interferometer based hyperspectral imaging technology implemented in an UAV has been introduced. In this research, we studied the possibilities of exploiting classified raster maps from hyperspectral data to produce a work task for a precision fertilizer application. The UAV flight campaign was performed in a wheat test field in Finland in the summer of 2012. Based on the campaign, we have classified raster maps estimating the biomass and nitrogen contents at approximately stage 34 in the Zadoks scale. We combined the classified maps with farm history data such as previous yield maps. Then we generalized the combined results and transformed it to a vectorized zonal task map suitable for farm machinery. We present the selected weights for each dataset in the processing chain and the resultant variable rate application (VRA) task. The additional fertilization according to the generated task was shown to be beneficial for the amount of yield. However, our study is indicating that there are still many uncertainties within the process chain.

  1. Case Study: Writing a Journal Case Study

    ERIC Educational Resources Information Center

    Prud'homme-Genereux, Annie

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  2. Case Study: Writing a Journal Case Study

    ERIC Educational Resources Information Center

    Prud'homme-Genereux, Annie

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  3. Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

    PubMed Central

    Antoniou, A.; Pharoah, P. D. P.; Narod, S.; Risch, H. A.; Eyfjord, J. E.; Hopper, J. L.; Loman, N.; Olsson, H.; Johannsson, O.; Borg, Å.; Pasini, B.; Radice, P.; Manoukian, S.; Eccles, D. M.; Tang, N.; Olah, E.; Anton-Culver, H.; Warner, E.; Lubinski, J.; Gronwald, J.; Gorski, B.; Tulinius, H.; Thorlacius, S.; Eerola, H.; Nevanlinna, H.; Syrjäkoski, K.; Kallioniemi, O.-P.; Thompson, D.; Evans, C.; Peto, J.; Lalloo, F.; Evans, D. G.; Easton, D. F.

    2003-01-01

    Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer, but the average magnitude of these risks is uncertain and may depend on the context. Estimates based on multiple-case families may be enriched for mutations of higher risk and/or other familial risk factors, whereas risk estimates from studies based on cases unselected for family history have been imprecise. We pooled pedigree data from 22 studies involving 8,139 index case patients unselected for family history with female (86%) or male (2%) breast cancer or epithelial ovarian cancer (12%), 500 of whom had been found to carry a germline mutation in BRCA1 or BRCA2. Breast and ovarian cancer incidence rates for mutation carriers were estimated using a modified segregation analysis, based on the occurrence of these cancers in the relatives of mutation-carrying index case patients. The average cumulative risks in BRCA1-mutation carriers by age 70 years were 65% (95% confidence interval 44%–78%) for breast cancer and 39% (18%–54%) for ovarian cancer. The corresponding estimates for BRCA2 were 45% (31%–56%) and 11% (2.4%–19%). Relative risks of breast cancer declined significantly with age for BRCA1-mutation carriers (P trend .0012) but not for BRCA2-mutation carriers. Risks in carriers were higher when based on index breast cancer cases diagnosed at <35 years of age. We found some evidence for a reduction in risk in women from earlier birth cohorts and for variation in risk by mutation position for both genes. The pattern of cancer risks was similar to those found in multiple-case families, but their absolute magnitudes were lower, particularly for BRCA2. The variation in risk by age at diagnosis of index case is consistent with the effects of other genes modifying cancer risk in carriers. PMID:12677558

  4. Reconstructing the lake-level history of former glacial lakes through the study of relict wave-cut terraces: the case of Lake Ojibway (eastern Canada)

    NASA Astrophysics Data System (ADS)

    Roy, Martin; Veillette, Jean; Daubois, Virginie

    2014-05-01

    The reconstruction of the history of former glacial lakes is commonly based on the study of strandlines that generally consist of boulder ridges, sandy beaches and other near-shore deposits. This approach, however, is limited in some regions where the surficial geology consists of thick accumulation of fine-grained glaciolacustrine sediments that mask most deglacial landforms. This situation is particularly relevant to the study of Lake Ojibway, a large proglacial lake that developed in northern Ontario and Quebec following the retreat of the southern Laurentide ice sheet margin during the last deglaciation. The history of Ojibway lake levels remains poorly known, mainly due to the fact that this lake occupied a deep and featureless basin that favored the sedimentation of thick sequences of rhythmites and prevented the formation of well-developed strandlines. Nonetheless, detailed mapping revealed a complex sequence of discontinuous small-scale cliffs that are scattered over the flat-lying Ojibway clay plain. These terrace-like features range in size from 4 to 7 m in height and can be followed for 10 to 100's of meters. These small-scale geomorphic features are interpreted to represent raised shorelines that were cut into glaciolacustrine sediments by lakeshore erosional processes (i.e., wave action). These so-called wave-cut scarps (WCS) occur at elevations ranging from 3 to 30 m above the present level of Lake Abitibi (267 m), one of the lowest landmarks in the area. Here we evaluate the feasibility of using this type of relict shorelines to constrain the evolution of Ojibway lake levels. For this purpose, a series of WCS were measured along four transects of about 40 km in length in the Lake Abitibi region. The absolute elevation of 154 WCS was determined with a Digital Video Plotter software package using 1:15K air-photos, coupled with precise measurements of control points, which were measured with a high-precision Global Navigation Satellite System tied up to

  5. Global, local and focused geographic clustering for case-control data with residential histories

    PubMed Central

    Jacquez, Geoffrey M; Kaufmann, Andy; Meliker, Jaymie; Goovaerts, Pierre; AvRuskin, Gillian; Nriagu, Jerome

    2005-01-01

    Background This paper introduces a new approach for evaluating clustering in case-control data that accounts for residential histories. Although many statistics have been proposed for assessing local, focused and global clustering in health outcomes, few, if any, exist for evaluating clusters when individuals are mobile. Methods Local, global and focused tests for residential histories are developed based on sets of matrices of nearest neighbor relationships that reflect the changing topology of cases and controls. Exposure traces are defined that account for the latency between exposure and disease manifestation, and that use exposure windows whose duration may vary. Several of the methods so derived are applied to evaluate clustering of residential histories in a case-control study of bladder cancer in south eastern Michigan. These data are still being collected and the analysis is conducted for demonstration purposes only. Results Statistically significant clustering of residential histories of cases was found but is likely due to delayed reporting of cases by one of the hospitals participating in the study. Conclusion Data with residential histories are preferable when causative exposures and disease latencies occur on a long enough time span that human mobility matters. To analyze such data, methods are needed that take residential histories into account. PMID:15784151

  6. Case-History Explorations of Scientifically Significant Earth-System Events

    NASA Astrophysics Data System (ADS)

    Hall, M. K.; Walker, C. S.; Mayhew, M. A.

    2007-12-01

    We are developing case histories of recent and ancient natural disasters to provide students a means of learning fundamental earth system science and applying their new understanding to mitigating disasters in the future. We distinguish case histories from case studies in that they investigate real problems that are likely to recur, as opposed to hypothetical but realistic problem scenarios. Students explore the scientific and societal conditions that caused or fueled a disaster; investigate whether the outcome might have been different under different conditions; explore how the disaster has shaped our scientific and societal understanding of such events; and propose appropriate responses and preparation measures for future events. Each case history allows for multiple directions of investigation by individuals or teams. The case histories incorporate actual datasets used by scientists to analyze the event, in addition to analysis tools such as GIS, Excel, and Google Earth. These classroom resources are appropriate for undergraduate earth system majors from first year to third year. We have completed and are field testing case histories for the 1994 M6.7 Northridge earthquake and the Super Tornado Outbreak of 1974, as well as other notable tornado outbreaks. Additionally, we are developing case histories for the 1700 Cascadia mega-tsunami and the 2005 Hurricane Katrina. Research studies of each of these events have resulted in significant changes to our understanding of the earth processes that caused them, and have spawned renewed interest in hazard mitigation. Each case history also incorporates the human element, presented from both a scientific and eyewitness perspective. Field testing includes evaluation of scientific accuracy, usability and pedagogical effectiveness, as described in the DLESE peer-review-system criteria (www.dlese-project.org/review_criteria.html) by field testers and external technical experts.

  7. Squamous cell carcinoma of the oral cavity and oropharynx in patients aged 18-45 years: A case-control study to evaluate the risk factors with emphasis on stress, diet, oral hygiene, and family history.

    PubMed

    Dholam, K P; Chouksey, G C

    2016-01-01

    Increasing incidence of squamous cell carcinoma (SCC) of the oral cavity and oropharynx is reported in young adults. However, there is a paucity regarding etiology and risk factors. To evaluate the exposure potential carcinogenic factors among a sample aged 45 years and younger, diagnosed with SCC of the oral cavity and oropharynx. Eighty-five case samples aged 18-45 years, diagnosed with SCC of the oral cavity and oropharynx were compared with 85 controls who had never had cancer, matched for age and sex. This study was conducted by questionnaire-based interviews. Questionnaire contained items about exposure to the following risk factors: Caries prevalence, oral hygiene status, dental trauma, dental visit, stress, family history of cancer, environmental exposure to potential carcinogens, diet, body mass index (BMI), habits such as smoking, tobacco chewing, betel quid/pan, or supari. Odds ratios (ORs) of oral and pharyngeal cancer and the corresponding 95% confidence intervals were estimated using multiple logistic regression models. P< 0.05 was considered statistically significant. Elevated OR was seen in young adults who had poor oral hygiene, stress, dental trauma, low BMI, family history of cancer, exposure to environmental carcinogens, and habit of placement of quid for 11-20 years. An increased risk of oral and pharyngeal cancer was seen in cases who had poor oral hygiene, stress, dental trauma, low BMI, family history of cancer, exposure to environmental carcinogens, and habit of placement of quid.

  8. Thermal evolution of Lower Paleozoic sedimentary successions from organic and inorganic studies: the case history of the Holy Cross Mountains (central Poland)

    NASA Astrophysics Data System (ADS)

    Trolese, Matteo; Stefano Celano, Antonio; Corrado, Sveva; Caricchi, Chiara; Schito, Andrea; Aldega, Luca

    2015-04-01

    The rapid increase in shale gas production in the USA has triggered a growing interest in unconventional resources in Eastern and Northern Europe. In this framework, the potential shale gas reserves in Poland are the most promising in Europe, extending from the Baltic Sea to the Ukraine border. In this area, the Baltic, Podlasie and Lublin basins have already become objective of shale gas exploration and the Holy Cross Mountains (HCM, Central Poland) represents the outcropping analog of the buried targeted Lower Paleozoic successions, providing a unique opportunity to study and assess source rock potential. In this work, we provide new thermal maturity data of Paleozoic rocks exposed in the HCM. A multi-method approach, coupling organic matter/graptolites (i.e., marine organoclasts) optical analysis and X-ray diffraction of clay-sized fraction of sediments, was applied to constrain the burial - thermal evolution of the sedimentary succession. The investigated area of the HCM includes two different tectonic blocks: the Łysogóry region to the North and the Kielce region to the South, separated by the Holy Cross Fault (HCF). lllite content in mixed layer illite-smectite determinations and vitrinite/graptolites reflectance measurements (Roeq%), performed on samples (Cambrian - Devonian) collected from both the regions, show a substantial difference between the two blocks in terms of thermal maturity and burial history. Roeq% values in the southern block range from 0.5% to 1.0%, with few exceptions, indicating early to mid-mature stage of hydrocarbon generation. Samples collected in the northern block show much higher values, mainly from 1.2% up to 1.7%, representative of the gas generation window. The I-S ordering type also shows relevant differences in the two blocks. In the southern block, mixed-layered clay minerals varies from R1 (short-range) to R3 (long-range), whereas R3 structures are recorded in the northern block. Vitrinite reflectance and mixed-layer I

  9. A Middle to Late Holocene avulsion history of the Euphrates river: a case study from Tell ed-Dēr, Iraq, Lower Mesopotamia

    NASA Astrophysics Data System (ADS)

    An Heyvaert, Vanessa Mary; Baeteman, Cecile

    2008-12-01

    Geoarchaeological research was performed to reconstruct the floodplain history in the surroundings of two ancient Mesopotamian cities: Tell ed-Dēr and Sippar. The mapping of the floodplain is based on facies analyses of the sedimentary succession of 225 hand-operated boreholes. The archaeological sites Tell ed-Dēr and Sippar are closely linked to a palaeochannelbelt of the Euphrates, located in the western part of the study area. Channel activity started at least in ca 3100 BC/5050 cal BP, until ca 1400-1000 BC/3350-2950 cal BP. The channel belt was part of an avulsion driven multiple Euphrates channel network that gradually became abandoned from the second half of the 2nd millennium BC. A second mapped Euphrates, Tigris or Joint Euphrates -Tigris palaeochannel belt became abandoned well before 3100 BC. Examples of natural processes as well as human interactions triggering avulsion are given. Moreover, textual, archaeological and geological data show clearly that flood-control techniques and the construction of large-scale dikes seemed to be a common practice.

  10. Thermal, trophic and metabolic life histories of inaccessible fishes revealed from stable-isotope analyses: a case study using orange roughy Hoplostethus atlanticus.

    PubMed

    Trueman, C N; Rickaby, R E M; Shephard, S

    2013-12-01

    A time-resolved record of inhabited water depth, metabolic rate and trophic behaviour of the orange roughy Hoplostethus atlanticus was recovered from combined stable-isotope analyses of otolith and muscle tissue. The results demonstrate that H. atlanticus from the north-east Atlantic Ocean have a complex life history with three distinct depth-stratified life stages. Early juvenile H. atlanticus occupy relatively shallow habitats, juvenile H. atlanticus show a deep-demersal phase, rising at sexual maturity, and adult H. atlanticus exploit increasingly deep habitats with increasing age. At all sampled sizes, H. atlanticus muscle tissues have an isotopic composition suggesting a benthic rather than benthopelagic or pelagic diet. Isotopic measures of relative metabolic rate provide an insight into energy partitioning throughout ontogeny. Hoplostethus atlanticus have relatively low metabolic rates compared to coexisting deep-water benthic fishes, consistent with their unusually high longevity. Surprisingly, lifetime fastest growth rates are achieved during juvenile stages when otolith isotopes imply deep-water residency and relatively low metabolic rates. Fast growth may be sustained during a period of high efficiency associated with reduced metabolic costs of prey capture or predator evasion. The stable-isotope approach can be applied to any teleost and provides a rapid, cost-effective technique for studying deep-water fish communities. © 2013 The Fisheries Society of the British Isles.

  11. Risk factors for uterine leiomyoma: a practice-based case-control study. I. African-American heritage, reproductive history, body size, and smoking.

    PubMed

    Faerstein, E; Szklo, M; Rosenshein, N

    2001-01-01

    The authors conducted a case-control study among premenopausal women in the Baltimore, Maryland, area to examine the associations of uterine leiomyoma with ethnicity and hormone-related characteristics. Cases of uterine leiomyoma (n = 318) were surgically or sonographically first confirmed between January 1990 and June 1993. A total of 394 controls were selected from women who were visiting their gynecologist for a routine checkup. Data were collected through telephone interviews and abstraction of medical records; 77.8% of eligible cases and 78.0% of eligible controls were interviewed. Positive adjusted associations were observed between risk of uterine leiomyoma and self-described African-American ethnicity (vs. Whites: odds ratio (OR) = 9.4; 95% confidence interval (CI): 5.7, 15.7), early menarche (<11 years vs. >13 years: OR = 2.4; 95% CI: 1.1, 5.6), and high body mass index (upper quartile vs. lower quartile: OR = 2.3; 95% CI: 1.4, 3.8). Inverse associations were observed with use of oral contraceptives (current use vs. never use: OR = 0.2, 95% CI: 0.1, 0.6) and duration of smoking (> or =19 years vs. never: OR = 0.6; 95% CI: 0.4, 1.1). Younger ages at infertility diagnosis and at first and last childbirth were more common among cases; however, analyses of data on tumor location suggested that these associations represent predominantly consequences of uterine leiomyoma. These results suggest that development of uterine leiomyoma is associated with increased exposure to ovarian hormones. Possible reasons for the very elevated risk among African-American women need further investigation.

  12. Methodology for lognormal modelling of malignant pleural mesothelioma survival time distributions: a study of 5580 case histories from Europe and USA

    NASA Astrophysics Data System (ADS)

    Mould, Richard F.; Lahanas, Michael; Asselain, Bernard; Brewster, David; Burgers, Sjaak A.; Damhuis, Ronald A. M.; DeRycke, Yann; Gennaro, Valerio; Szeszenia-Dabrowska, Neonila

    2004-09-01

    A truncated left-censored and right-censored lognormal model has been validated for representing pleural mesothelioma survival times in the range 5-200 weeks for data subsets grouped by age for males, 40-49, 50-59, 60-69, 70-79 and 80+ years and for all ages combined for females. The cases available for study were from Europe and USA and totalled 5580. This is larger than any other pleural mesothelioma cohort accrued for study. The methodology describes the computation of reference baseline probabilities, 5-200 weeks, which can be used in clinical trials to assess results of future promising treatment methods. This study is an extension of previous lognormal modelling by Mould et al (2002 Phys. Med. Biol. 47 3893-924) to predict long-term cancer survival from short-term data where the proportion cured is denoted by C and the uncured proportion, which can be represented by a lognormal, by (1 - C). Pleural mesothelioma is a special case when C = 0.

  13. Magma mixing, crustal contamination, contamination before chemical analysis or complex history? The case study from the Wołek Hill, SW Poland

    NASA Astrophysics Data System (ADS)

    Nowak, Monika

    2015-04-01

    Wołek Hill is one of the smallest exposures from ca. 300 occurrences of Cenozoic volcanic rocks from SW Poland. The outcrop is located about 100 km SW from Wrocław and belongs to the Złotoryja Volcanic Field, which is one of the largest volcanic fields in the Polish part of the Central European Volcanic Province (Ladenberger et al. 2006). The volcanic body, which is about 20 m wide, cross-cuts older Permian volcanic rocks (trachyandesites and rhyolites) and is well exposed in an old abandoned quarry. The occurrence was studied in detail because of great amount of mantle and crustal xenoliths brought to the surface by magma. Wołek Hill is one of the two occurrences in SW Poland where amphibole crystals were recognized as results of modal metasomatism in lithospheric mantle (Nowak et al. 2012). The volcanic rock from Wołek Hill represents complex history, difficult to explain by simple model. The rock was classified as basanite (Nowak, 2012). Its texture is porphyritic to glomeroporphyritic, olivine (Ol) and clinopyroxene (Cpx) occurs as phenocrysts, Cpx is also the dominant phase in the groundmass. Wołek Hill basanite differs from other exposures in Złotoryja Volcanic Field by presence of xenocrysts of Ol and Cpx from mantle rocks and also quartz (Qrtz) and feldspars (Feld) xenocrysts from crustal rocks. Those xenocrysts with additional carbonate veins, probably related with post-volcanic processes, were a great difficulty during rock preparation for whole-rock and isotopic analyses. The complex history of Wołek Hill basanite is visible in its chemical content (slight increase of SiO2, positive Pb anomaly, 87Sr/86Sr and 143Nd/144Nd values), but also in its petrography (e.g. by three types of olivine phenocrysts Fo82-91 with differences in zonation patterns reflecting Fo content; the most abundant are phenocrysts with normal zoning, but also crystals with opposite zoning and oscillatory zoning were recognised). According to available data from the basanite

  14. Fluoxetine: a case history of its discovery and preclinical development.

    PubMed

    Perez-Caballero, Laura; Torres-Sanchez, Sonia; Bravo, Lidia; Mico, Juan Antonio; Berrocoso, Esther

    2014-05-01

    Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS. Advances in drug discovery have widened the therapeutic options with the synthesis of so-called selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine. The aim of this case history is to describe and discuss the pharmacokinetic and pharmacodynamic profiles of fluoxetine, including its acute effects and the adaptive changes induced after long-term treatment. Furthermore, the authors review the effect of fluoxetine on neuroplasticity and adult neurogenesis. In addition, the article summarises the preclinical behavioural data available on fluoxetine's effects on depressive-like behaviour, anxiety and cognition as well as its effects on other diseases. Finally, the article describes the seminal studies validating the antidepressant effects of fluoxetine. Fluoxetine is the first selective SSRI that has a recognised clinical efficacy and safety profile. Since its discovery, other molecules that mimic its mechanism of action have been developed, commencing a new age in the treatment of depression. Fluoxetine has also demonstrated utility in the treatment of other disorders for which its prescription has now been approved.

  15. Detailed family history of diabetes identified children at risk of type 2 diabetes: a population-based case-control study.

    PubMed

    Wei, Jung-Nan; Li, Hung-Yuan; Wang, Yi-Chia; Chuang, Lee-Ming; Lin, Mao-Shin; Lin, Cheng-Hsin; Sung, Fung-Chang

    2010-06-01

    Recently, the incidence of type 2 diabetes (T2D) in children has increased dramatically. Mass screening is suffering and costly. It remains unknown if a detailed family diabetes mellitus history (FDMH) can identify children with different risks of T2D. This study investigated how FDMH was associated with childhood T2D. From 1992 to 1997, a nationwide survey conducted in Taiwan for all 3 000 000 school children aged between 6 and 18 yr identified 1966 children with diabetes. For comparison, 1780 children were randomly selected as the control group from all students with normal fasting glycemia (NFG). Telephonic Interviews were conducted using questionnaire for detailed FDMH. In the present analysis, 505 children with T2D and 619 children with NFG were enrolled. Children with more family members having diabetes were more likely to have T2D. Children with the parental FDMH had a higher risk for T2D than children with the grandparental FDMH; the odds ratios (ORs) were 2.61 (95% confidence interval (CI) 1.25-5.48, p < 0.05) for boys and 6.47 (95% CI 2.69-15.6, p < 0.05) for girls, adjusting for age, birth weight, gestational age and body mass index (BMI) z-score. Children with maternal FDMH had a higher risk for T2D than children with paternal FDMH, and much greater in boys (OR = 29.5, 95% CI 3.67-237, p < 0.05) than in girls (OR = 7.63, 95% CI 2.05-28.4, p < 0.05), adjusted for age, birth weight, gestational age, BMI z-score, and FDMH in grandparents. Children with parental FDMH, especially the maternal FDMH, have an elevated risk for T2D. Detailed FDMH is a convenient alternative to identify children with different risks of T2D.

  16. Oral History and the Black Studies Program.

    ERIC Educational Resources Information Center

    Simmons, Henry E.

    Black Studies means an indepth investigation of the Black Experience. Without oral history methods, this will be prostituted to mean a superficial view of opinions set forth by white society. All the broad areas of Black scholarship must begin to relate to the problems of capturing the life of the race on tape and retaining it for posterity. Oral…

  17. Identifying the History and Logic of Negative, Ambivalent, and Positive Responses to Literature: A Case-Study Analysis of Cultural Models

    ERIC Educational Resources Information Center

    Thein, Amanda Haertling

    2009-01-01

    This paper begins with the assumption that the interpretive practices people acquire in social worlds often transfer to their stances toward and interpretations of worlds encountered in literature (Beach, Thein, & Parks, 2007). The goal of this paper is to identify the history and logic behind one student's negative, ambivalent, and positive…

  18. Collapse of a Multinational State: The Case of Yugoslavia. A Curriculum Unit for History and Social Studies. Recommended for Grades 9 through Community College.

    ERIC Educational Resources Information Center

    Steinbeck, Reinhold; And Others

    This curriculum unit teaches students about nationalism within the context of Europe and is designed to help better understand the history of Yugoslavia and why Yugoslavia fell apart. The unit focuses on Yugoslavia as a multinational state and how the federation was organized during different historical time periods. There are three lessons in the…

  19. Collapse of a Multinational State: The Case of Yugoslavia. A Curriculum Unit for History and Social Studies. Recommended for Grades 9 through Community College.

    ERIC Educational Resources Information Center

    Steinbeck, Reinhold; And Others

    This curriculum unit teaches students about nationalism within the context of Europe and is designed to help better understand the history of Yugoslavia and why Yugoslavia fell apart. The unit focuses on Yugoslavia as a multinational state and how the federation was organized during different historical time periods. There are three lessons in the…

  20. A Halifax Case Study that Offers an Alternative History of Care Provided by Local Authorities under the 1913 Mental Deficiency Act

    ERIC Educational Resources Information Center

    Dale, Pamela

    2014-01-01

    Institutions, and their problems, have traditionally dominated learning disability histories. We know far more about what happened in areas where councils established and/or enthusiastically used local institutions than other places. Local authorities less committed to institutional care must have relied more on family and other carers. This may…

  1. Identifying the History and Logic of Negative, Ambivalent, and Positive Responses to Literature: A Case-Study Analysis of Cultural Models

    ERIC Educational Resources Information Center

    Thein, Amanda Haertling

    2009-01-01

    This paper begins with the assumption that the interpretive practices people acquire in social worlds often transfer to their stances toward and interpretations of worlds encountered in literature (Beach, Thein, & Parks, 2007). The goal of this paper is to identify the history and logic behind one student's negative, ambivalent, and positive…

  2. Risk factors for Taenia saginata cysticercus infection in cattle in the United Kingdom: A farm-level case-control study and assessment of the role of movement history, age and sex.

    PubMed

    Marshall, L R; Prakashbabu, B Chengat; Ferreira, J Pinto; Buzdugan, S N; Stärk, K D C; Guitian, J

    2016-12-01

    Bovine cysticercosis is caused by Taenia saginata cysticercus, the larval stage of the human tapeworm Taenia saginata. Recent European initiatives have highlighted the poor sensitivity of current surveillance for this parasite in cattle at slaughter; calling for more targeted, risk based and cost effective methods of T. saginata cysticercus detection. The aim of this study was to provide evidence that could inform such improved meat inspection activities in the United Kingdom (UK). The study included three components: (i) a farm-level case control study; (ii) the characterization of the network of movements of T. saginata cysticercus infected and non-infected animals, and an assessment of the strength of association between having passed through a farm that had previously originated an infected animal and the risk of infection; (iii) the assessment of the relationship between bovine age and gender and risk of infection. Abattoir records and cattle movement history data were used to identify farms of likely acquisition of infection (case farms) and a suitable control group. A questionnaire was used to gather farm-level characteristics and logistic regression was carried out to identify farm-level risk factors for the production of cattle found to be infected at slaughter. The case-control study provided evidence that farms situated close to a permanent potential source of human faecal contamination, and farms which used manure from animals other than cattle, were at higher risk of producing cattle later found to be infected with T. saginata cysticercus at slaughter. No other farm characteristics were identified as a risk factor for this. Analysis of the networks of animal movements showed that some individual farms played a key role as a source of T. saginata cysticercus infection; it was estimated that cattle with a history of being on a farm which previously appeared in the movement history of an infected animal were 4.27 times (P<0.001; 95% CI: 3.3-5.52) more

  3. Predictive seismic modeling case history from the Niger delta

    SciTech Connect

    Idowu, A.O. )

    1993-09-01

    Seismic modeling techniques provide the mechanics for simulating the geology of the subsurface by depicting the impact of a propagating seismic wavefront on subsurface structures. In practice, seismic data have been used to map the geometry of events in the subsurface, mainly from reflection continuity and the character of reflection packages. In the Niger delta, recent developments in stratigraphic exploration has induced the examination of more subtle features of reflection, mainly polarity, amplitude, and waveform to define the limits of seismic resolution and hence predict the geometry of subsurface fluid and solid interfaces. The case history discussed here involved interpretative study for defining the fluid contents of prospective oil and gas leads as indicated by anomalous seismic events on a Niger delta field located in a water depth of 25 m. An appropriate source signal (5-35 Hertz minimum phase) is selected, and the wavelet is convolved with a practical geologic model to obtain a synthetic seismogram. By an interactive process involving slight modifications in the geologic model, a synthetic seismogram is ultimately derived that matches a field signal, thus providing a more accurate prediction of the geological formation under study. The technique was effect (as confirmed by later drilling) in appraising the fluid contents of the targeted pay zones encountered at gas/water, oil/water, and gas/oil/water contacts in the O field, located in the eastern offshore area of the Niger delta. The method further demonstrated that structural and stratigraphic modeling are effective tools for testing the mapability of a geologic concept and are able to evaluate the significance of reflectivity changes or anomalies on uncalibrated seismic data.

  4. Combining geophysical data and calcite twin stress inversion to refine the tectonic history of subsurface and offshore provinces: A case study on the Cooper-Eromanga Basin, Australia

    NASA Astrophysics Data System (ADS)

    Kulikowski, David; Amrouch, Khalid

    2017-03-01

    The use of core samples, borehole image logs, and seismic data is common practice for obtaining valuable structural data; however, these data are often obtained in isolation from other methods and not usually used for paleostress inversion processes. Therefore, for the first time, we present a new approach for constraining paleoprincipal stress orientations and regimes by integrating geophysical data (seismic and well data) with calcite twin principal stress orientation inversion analysis to refine the evolution of entirely subsurface or offshore basins; a case study on the subsurface Cooper-Eromanga Basin, Australia. Calcite samples were collected from oriented core, natural fracture data collected from borehole image logs, and fault data interpreted from three-dimensional seismic surveys. The analysis of microscale, mesoscale and macroscale data constrained the paleoprincipal stress orientations and regimes of six successive tectonic events: (1) NNW-SSE oriented strike-slip Carboniferous Alice Springs event; (2) SE-NW oriented compressional Mid-Permian event; (3) NE-SW oriented strike-slip Late Permian Daralingie event; (4) E-W compressional Late Triassic Hunter-Bowen event; (5) E-W compressional Late Cretaceous event; and (6) N-S compressional Paleogene event. This study shows the applicability of integrating geophysics with calcite twin stress inversion to decipher the tectonic evolution of entirely subsurface and offshore provinces.

  5. A case history: from traumatic repetition towards psychic representability.

    PubMed

    Bichi, Estela L

    2008-06-01

    This paper is devoted principally to a case history concerning an analytic process extending over a period of almost ten years. The patient is B, who consulted the author after a traumatic episode. Although that was her reason for commencing treatment, a history of previous traumatogenic situations, including a rape during her adolescence, subsequently came to light. The author describes three stages of the treatment, reflected in three different settings in accordance with the work done by both patient and analyst in enabling B to own and work through her infantile and adult traumatic experiences. The process of transformation of traumatic traces lacking psychic representation, which was undertaken by both members of the analytic couple from the beginning of the treatment, was eventually approached in a particular way on the basis of their respective creative capacities, which facilitated the patient's psychic progress towards representability and the possibility of working through the experiences of the past. Much of the challenge of this case involved the analyst's capacity to maintain and at the same time consolidate her analytic posture within her internal setting, while doing her best to overcome any possible misfit (Balint, 1968) between her own technique and the specific complexities of the individual patient. The account illustrates the alternation of phases, at the beginning of the analysis, of remembering and interpretation on the one hand and of the representational void and construction on the other. In the case history proper and in her detailed summing up, the author refers to the place of the analyst during the analytic process, the involvement of her psychic functioning, and the importance of her capacity to work on and make use of her countertransference and self-analytic introspection, with a view to neutralizing any influence that aspects of her 'real person' might have had on the analytic field and on the complex processes taking place within

  6. Design aspects of zeppelin operations from case histories

    NASA Technical Reports Server (NTRS)

    Maiersperger, W. P.

    1975-01-01

    Some widely held beliefs concerning the practicability of rigid airships in air carrier operations are discussed. It is shown by a review of past operational experience, and some basic aerostatic theory, their actual record and the reasons for their demise. Problems of atmospheric density and temperature variations, meteorological factors, aerodynamic stability and control, and mooring difficulties are discussed and related to actual case histories. Structural and flight efficiencies are compared to airplane efficiencies for airplanes contemporary with the zeppelin as well as modern designs. The difficulty of supporting new, commercial airship developments on an economic basis is made clear.

  7. [Diagnostic investigation in emergency medicine: Why case history is crucial].

    PubMed

    Mirus, M; Heller, A R

    2017-04-01

    We present the preclinical case of a patient reporting chest pain. Pain impeded physical examination. Reviewing the patient's detailed medical history after analgesia revealed a connection between the reported pain and vomiting. This led to a suspicion of organ perforation. Thus, the patient was admitted to a surgical emergency room (ER) and Boerhaave's Syndrome was diagnosed. After deterioration in the ER, cardiopulmonal reanimation (CPR), and successful surgical treatment, the patient was transferred to the intensive care unit (ICU) seven hours after first contact.

  8. Case histories in the great power of steady misrepresentation.

    PubMed

    Todd, J T; Morris, E K

    1992-11-01

    The widespread misrepresentation of behaviorism in the scientific and popular literature has caused its contributions to the understanding of behavior to be systematically ignored or denied. This misrepresentation is manifested, in large part, as a form of academic folklore that codifies erroneous accounts of behaviorism's assumptions, findings, and goals. This article examines three representative "case histories" of the academic folklore about behaviorism: its alleged environmentalism, totalitarian aims, and intellectual intolerance. Because academic folklore has been highly resistant to the corrective efforts of behaviorists, explicit strategies are suggested for identifying and correcting folklore and for promoting more effective interdisciplinary communication.

  9. Case Studies for Effective Business Instruction.

    ERIC Educational Resources Information Center

    McAlister-Kizzier, Donna

    This book is designed as a resource for educators who teach business content in a variety of instructional settings. It contains case studies representing all functional areas of business, including corporate training, for grades 7 through graduate education. Chapter 1 provides an overview of the case study method. The history of the case method,…

  10. Labor Analgesia Consumption and Time to Neuraxial Catheter Placement in Women with a History of Surgical Correction for Scoliosis: A Case-Matched Study.

    PubMed

    Bauchat, Jeanette R; McCarthy, Robert J; Koski, Tyler R; Wong, Cynthia A

    2015-10-01

    Neuraxial analgesic techniques are the most effective form of labor analgesia. Small studies (9-21 patients), conducted 10 to 20 years ago, demonstrated successful neuraxial labor analgesia in only 50% to 66% of patients with surgical correction for scoliosis. Newer surgical techniques for scoliosis correction make the epidural space more accessible, but postsurgical changes may still alter the efficacy of neuraxial labor analgesia. The purpose of this prospective case-matched study was to compare hourly bupivacaine consumption and time to placement of neuraxial technique in laboring women with spinal instrumentation compared with women without previous back surgery. All women with previous spinal instrumentation surgery for scoliosis correction who requested neuraxial labor analgesia at Prentice Women's Hospital during the study period were approached. Control subjects were matched for anesthesiologist level of experience. The primary outcomes were bupivacaine consumption per hour of labor analgesia and time to placement of the neuraxial technique. Secondary outcomes included supplemental analgesia requirements and neuraxial analgesia failures and complications. Data from 41 women with surgical correction for scoliosis and 41 control subjects requesting neuraxial labor analgesia were analyzed. Obstetric and demographic characteristics of study participants were not different between groups. Median (interquartile range) hourly bupivacaine consumption was 15.2 mg/h (12.5-18.7) in the spinal instrumentation group and 14.2 mg/h (11.8-16.0) in the control group; the difference in medians was 1 mg/h (95% confidence interval [CI], -1.3 to 3.0; P = 0.38). The total bupivacaine consumption, number of manual reboluses, and number of subjects requiring greater bupivacaine concentrations did not differ between groups. Neuraxial analgesia failure occurred in 5 (12%) of women in the spinal instrumentation group but in none of the control patients (difference [95% CI], 12% [-0

  11. Life-history evolution in ants: the case of Cardiocondyla

    PubMed Central

    2017-01-01

    Ants are important components of most terrestrial habitats, and a better knowledge of the diversity of their life histories is essential to understand many aspects of ecosystem functioning. The myrmicine genus Cardiocondyla shows a wide range of colony structures, reproductive behaviours, queen and male lifespans, and habitat use. Reconstructing the evolutionary pathways of individual and social phenotypic traits suggests that the ancestral life history of Cardiocondyla was characterized by the presence of multiple, short-lived queens in small-sized colonies and a male polyphenism with winged dispersers and wingless fighters, which engage in lethal combat over female sexuals within their natal nests. Single queening, queen polyphenism, the loss of winged males and tolerance among wingless males appear to be derived traits that evolved with changes in nesting habits, colony size and the spread from tropical to seasonal environments. The aim of this review is to bring together the information on life-history evolution in Cardiocondyla and to highlight the suitability of this genus for functional genomic studies of adaptation, phenotypic plasticity, senescence, invasiveness and other key life-history traits of ants. PMID:28298341

  12. Life-history evolution in ants: the case of Cardiocondyla.

    PubMed

    Heinze, Jürgen

    2017-03-15

    Ants are important components of most terrestrial habitats, and a better knowledge of the diversity of their life histories is essential to understand many aspects of ecosystem functioning. The myrmicine genus Cardiocondyla shows a wide range of colony structures, reproductive behaviours, queen and male lifespans, and habitat use. Reconstructing the evolutionary pathways of individual and social phenotypic traits suggests that the ancestral life history of Cardiocondyla was characterized by the presence of multiple, short-lived queens in small-sized colonies and a male polyphenism with winged dispersers and wingless fighters, which engage in lethal combat over female sexuals within their natal nests. Single queening, queen polyphenism, the loss of winged males and tolerance among wingless males appear to be derived traits that evolved with changes in nesting habits, colony size and the spread from tropical to seasonal environments. The aim of this review is to bring together the information on life-history evolution in Cardiocondyla and to highlight the suitability of this genus for functional genomic studies of adaptation, phenotypic plasticity, senescence, invasiveness and other key life-history traits of ants.

  13. Role of thermal history in atomic dynamics of chalcogenide glass: A case study on Ge{sub 20}Te{sub 80} glass

    SciTech Connect

    Sharma, Yashika; Kalra, Geetanjali; Murugavel, Sevi

    2016-05-23

    The non-existence of thermodynamic equilibrium in glasses, their thermal history plays a very crucial role in explaining the relaxation behavior in various time scales and its configurational states. More importantly, the associated relaxation behavior is related mainly to the structural phenomenon of the glasses. Here, we report the dependence of quenching rate on the variation of structural units. The local structures of these glasses are monitored by recording the Raman spectroscopy and related to the different configurational states. The observed variations in structural differences are reflected in the measured density of the corresponding glasses. The quenching rate dependent of the relative fractions of edge-shared and corner-shared GeTe{sub 4} tetrahedral units are shown to be consistent with the corresponding variations in the measured density values.

  14. The evolutionary history and palaeo-ecology of primate predation: Macaca sylvanus from Plio-Pleistocene Europe as a case study.

    PubMed

    Meloro, Carlo; Elton, Sarah

    2012-01-01

    In this article we briefly review primate interactions with predators throughout their evolutionary history. Like today, predators of past primates were taxonomically diverse, including crocodilians, aquatic mammals, hyaenids, raptors and other primates. There is strong evidence for felid predation of extinct primates, with most work undertaken on the African Plio-Pleistocene fossil record. Felid predation of Plio-Pleistocene primates from other areas, including Europe, is much less well understood, so we explored co-occurrence and potential interaction between carnivorans (with particular reference to felids) and Macaca sylvanus, which was widespread and present in Europe from the late Miocene to the late Pleistocene. Over its tenure in the fossil record, M. sylvanus co-occurred with a diverse array of carnivorans, including canids and hyaenids, but medium-sized felids probably posed the most significant predation risk. It is likely, however, that human predation was a major factor contributing to macaque extinction in Europe.

  15. Annual variation of spawning cutthroat trout in a small western USA stream: a case study with implications for the conservation of potamodromous trout life history diversity

    USGS Publications Warehouse

    Bennett, Stephen; Al-Chokhachy, Robert; Roper, Brett B.; Budy, Phaedra

    2014-01-01

    Little is known about the variability in the spatial and temporal distribution of spawning potamodromous trout despite decades of research directed at salmonid spawning ecology and the increased awareness that conserving life history diversity should be a focus of management. We monitored a population of fluvial–resident Bonneville Cutthroat Trout Oncorhynchus clarkii utah in a tributary to the Logan River, Utah, from 2006 to 2012 to gain insight into the distribution and timing of spawning and what factors may influence these spawning activities. We monitored Bonneville Cutthroat Trout using redd surveys with multiple observers and georeferenced redd locations. We documented an extended spawning period that lasted from late April to mid-July. The onset, median, and end of spawning was best predicted by the mean maximum water temperature during the first 13 weeks of the year (F = 130. 4, df = 5, R2 = 0.96, P < 0.0001) with spawning beginning and ending earlier in years that had warmer water temperatures prior to spawning. The distribution of redds was clumped each year and the relative density of redds was greater in a reach dominated by dams constructed by beavers Castor canadensis. Both dam failure and construction appeared to be responsible for creating new spawning habitat that was quickly occupied, demonstrating rapid temporal response to local habitat changes. Bonneville Cutthroat Trout appeared to establish and defend a redd for up to 2 d, and spawning most often occurred between similar-sized individuals. Spawning surveys for potamodromous trout are an underutilized tool that could be used to better understand the distribution and timing of spawning as well as determine the size and trends of the reproducing portion of populations of management concern. Without efforts to document the diversity of this important aspect of potamodromous trout life history, prioritization of conservation will be problematic.

  16. Annual variation of spawning Cutthroat Trout in a small Western USA stream: A case study with implications for the conservation of potamodromous trout life history diversity

    USGS Publications Warehouse

    Bennett, Stephen; Al-Chokhachy, Robert K.; Roper, Brett B.; Budy, Phaedra

    2014-01-01

    Little is known about the variability in the spatial and temporal distribution of spawning potamodromous trout despite decades of research directed at salmonid spawning ecology and the increased awareness that conserving life history diversity should be a focus of management. We monitored a population of fluvial–resident Bonneville Cutthroat Trout Oncorhynchus clarkii utah in a tributary to the Logan River, Utah, from 2006 to 2012 to gain insight into the distribution and timing of spawning and what factors may influence these spawning activities. We monitored Bonneville Cutthroat Trout using redd surveys with multiple observers and georeferenced redd locations. We documented an extended spawning period that lasted from late April to mid-July. The onset, median, and end of spawning was best predicted by the mean maximum water temperature during the first 13 weeks of the year (F = 130. 4, df = 5, R2 = 0.96, P < 0.0001) with spawning beginning and ending earlier in years that had warmer water temperatures prior to spawning. The distribution of redds was clumped each year and the relative density of redds was greater in a reach dominated by dams constructed by beavers Castor canadensis. Both dam failure and construction appeared to be responsible for creating new spawning habitat that was quickly occupied, demonstrating rapid temporal response to local habitat changes. Bonneville Cutthroat Trout appeared to establish and defend a redd for up to 2 d, and spawning most often occurred between similar-sized individuals. Spawning surveys for potamodromous trout are an underutilized tool that could be used to better understand the distribution and timing of spawning as well as determine the size and trends of the reproducing portion of populations of management concern. Without efforts to document the diversity of this important aspect of potamodromous trout life history, prioritization of conservation will be problematic.

  17. The status of the study of optometry history.

    PubMed

    Goss, David A

    2007-01-01

    The status of optometry history was examined by searching online databases for publications on the history of optometry and the history of other health care professions and some medical specialties. There have been many fewer publications on the history of optometry than on most other health care professions or on medical specialties. Further, there are common misconceptions about optometry history even among its own practitioners. The importance of the study of optometry history is emphasized and suggestions to improve its status are discussed.

  18. INFLUENCE OF EXPOSURE HISTORY ON VITELLOGENIN INDUCTION IN MEDAKA: A CASE OF "ESTROGEN MEMORY"?

    EPA Science Inventory

    Influence of Exposure History on Vitellogenin Induction in Medaka: a Case of "Estrogen Memory"? (Abstract). Mar. Environ. Res. 50(1-5):196.

    In this study, we exposed female medaka to aqueous solutions of o,p'-DDT until tissues residues reached approximately 100 g/g. Male...

  19. Digital Tools Disrupting Tertiary Students' Notions of Disciplinary Knowledge: Cases in History and Tourism

    ERIC Educational Resources Information Center

    Cowie, Bronwen; Khoo, Elaine

    2014-01-01

    This paper reports on the findings from a two year research project that explored the potential of digital tools in support of teaching-learning across different disciplinary areas at a New Zealand university. Two courses (in History and Tourism) are case studied using data collected through interviews with lecturers, tutors and their students,…

  20. INFLUENCE OF EXPOSURE HISTORY ON VITELLOGENIN INDUCTION IN MEDAKA: A CASE OF "ESTROGEN MEMORY"?

    EPA Science Inventory

    Influence of Exposure History on Vitellogenin Induction in Medaka: a Case of "Estrogen Memory"? (Abstract). Mar. Environ. Res. 50(1-5):196.

    In this study, we exposed female medaka to aqueous solutions of o,p'-DDT until tissues residues reached approximately 100 g/g. Male...

  1. Clinical characteristics of patients with tinnitus evaluated with the Tinnitus Sample Case History Questionnaire in Japan: A case series.

    PubMed

    Kojima, Takashi; Kanzaki, Sho; Oishi, Naoki; Ogawa, Kaoru

    2017-01-01

    The Tinnitus Sample Case History Questionnaire was determined as a standardized questionnaire for obtaining patient case histories and for characterizing patients into subgroups at the Tinnitus Research Initiative in 2006. In this study, we developed a Japanese version of this questionnaire for evaluating the clinical characteristics of patients with tinnitus. The Japanese version of the questionnaire will be available for evaluating treatments for tinnitus and for comparing data on tinnitus in research centers. To evaluate the clinical characteristics of patients with tinnitus in Japan using a newly developed Japanese version of Tinnitus Sample Case History Questionnaire. This was a prospective study based on patient records. University hospitals, general hospitals, and clinics. We collected patient data using a Japanese translated version of the Tinnitus Sample Case History Questionnaire. In total, 584 patients who visited our institutions in Japan between August 2012 and March 2014 were included (280 males and 304 females; age 13-92 years; mean age, 60.8). We examined patients after dividing them into two groups according to the presence or absence of hyperacusis. The collected results were compared with those from the Tinnitus Research Initiative database. Compared with the TRI database, there were significantly more elderly female patients and fewer patients with trauma-associated tinnitus. There was a statistically lower ratio of patients with hyperacusis. We found that patients with tinnitus in addition to hyperacusis had greater tinnitus severity and exhibited higher rates of various complications. The Japanese version of the Tinnitus Sample Case History Questionnaire developed in this study can be a useful tool for evaluating patients with tinnitus in Japan. The results of this multicenter study reflect the characteristics of patients with tinnitus who require medical care in Japan. Our data provides a preliminary basis for an international comparison of

  2. [Current Clinical Variables in Schizophrenia Cases with Suicide Attempt History].

    PubMed

    Sağlam Aykut, Demet; Civil Arslan, Filiz; Özkorumak Karagüzel, Evrim; Karakullukçu, Serdar; Tiryaki, Ahmet

    2017-01-01

    High suicide risk was shown to be related with depression and low quality of life in studies investigating clinical variables related to suicidal behavior. The aim of this study was to investigate the effects of a suicide attempt on clinical presentation by comparing sociodemographic variables, clinical signs, symptoms of depression, quality of life, social functionality, and reported adverse drug reactions in schizophrenic patients with and without suicide. Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale (CDS), Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), Social Functioning Scale (SFS), and Udvalg for Kliniske Undersøgelser Side Effect Rating Scale (UKU) were administered to 115 patients with schizophrenia. 44.3% of patients had at least one suicide attempt. Among sociodemographic variables, a family history of suicide, smoking, and total duration of disease were significantly higher in patients with suicide history than without. Scores of CDS and UKU subscores were significantly higher, and quality of life and social occupation in social functionality were significantly lower in patients with a history of suicide. In correlation analysis, CSD was negatively correlated with Q-LES-Q and independency/performance subscore of SFI, and positively correlated with UKU-Neurological subscore. In line with this data, suicidal behavior may be suggested to affect clinical presentation and course characteristic of schizophrenic patients. Additional treatments towards factors that may impact on the clinical course and social support programs might be suggested for these patients.

  3. The volcanic history of Volcán Alcedo, Galápagos Archipelago: a case study of rhyolitic oceanic volcanism

    USGS Publications Warehouse

    Geist, Dennis J.; Howard, Keith A.; Jellinek, A. Mark; Rayder, Scott

    1994-01-01

    Volcán Alcedo is one of the seven western Galápagos shields and is the only active Galápagos volcano known to have erupted rhyolite as well as basalt. The volcano stands 4 km above the sea floor and has a subaerial volume of 200 km3, nearly all of which is basalt. As Volcán Alcedo grew, it built an elongate domal shield, which was partly truncated during repeated caldera-collapse and partial-filling episodes. An outward-dipping sequence of basalt flows at least 250 m thick forms the steepest (to 33°) flanks of the volcano and is not tilted; thus a constructional origin for the steep upper flanks is favored. About 1 km3 of rhyolite erupted late in the volcano's history from at least three vents and in 2–5 episodes. The most explosive of these produced a tephra blanket that covers the eastern half of the volcano. Homogeneous rhyolitic pumice is overlain by dacite-rhyolite commingled pumice, with no stratigraphic break. The tephra is notable for its low density and coarse grain size. The calculated height of the eruption plume is 23–30 km, and the intensity is estimated to have been 1.2x108 kg/s. Rhyolitic lavas vented from the floor of the caldera and from fissures along the rim overlie the tephra of the plinian phase. The age of the rhyolitic eruptions is ≤120 ka, on the basis of K-Ar ages. Between ten and 20 basaltic lava flows are younger than the rhyolites. Recent faulting resulted in a moat around part of the caldera floor. Alcedo most resently erupted sometime between 1946 and 1960 from its southern flank. Alcedo maintains an active, transient hydrothermal system. Acoustic and seismic activity in 1991 is attributed to the disruption of the hydrothermal system by a regional-scale earthquake.

  4. Quantitative Morphologic Analysis of Boulder Shape and Surface Texture to Infer Environmental History: A Case Study of Rock Breakdown at the Ephrata Fan, Channeled Scabland, Washington

    NASA Technical Reports Server (NTRS)

    Ehlmann, Bethany L.; Viles, Heather A.; Bourke, Mary C.

    2008-01-01

    Boulder morphology reflects both lithology and climate and is dictated by the combined effects of erosion, transport, and weathering. At present, morphologic information at the boulder scale is underutilized as a recorder of environmental processes, partly because of the lack of a systematic quantitative parameter set for reporting and comparing data sets. We develop such a parameter set, incorporating a range of measures of boulder form and surface texture. We use standard shape metrics measured in the field and fractal and morphometric classification methods borrowed from landscape analysis and applied to laser-scanned molds. The parameter set was pilot tested on three populations of basalt boulders with distinct breakdown histories in the Channeled Scabland, Washington: (1) basalt outcrop talus; (2) flood-transported boulders recently excavated from a quarry; and (3) flood-transported boulders, extensively weathered in situ on the Ephrata Fan surface. Size and shape data were found to distinguish between flood-transported and untransported boulders. Size and edge angles (approximately 120 degrees) of flood-transported boulders suggest removal by preferential fracturing along preexisting columnar joints, and curvature data indicate rounding relative to outcrop boulders. Surface textural data show that boulders which have been exposed at the surface are significantly rougher than those buried by fan sediments. Past signatures diagnostic of flood transport still persist on surface boulders, despite ongoing overprinting by processes in the present breakdown environment through roughening and fracturing in situ. Further use of this quantitative boulder parameter set at other terrestrial and planetary sites will aid in cataloging and understanding morphologic signatures of environmental processes.

  5. Data reduction for prediction: a case study on robust coding of age and family history for the risk of having a genetic mutation.

    PubMed

    Steyerberg, Ewout W; Balmaña, Judith; Stockwell, David H; Syngal, Sapna

    2007-12-30

    Data reduction is often desired in the development of a prediction model, for example for effects of age and family history in the identification of subjects having a genetic mutation. We aimed to evaluate a strategy for model simplification by robust coding of related predictors. We considered 898 patients suspected of having Lynch syndrome, which is caused primarily by mutations in the mismatch repair genes, MLH1 or MSH2. The presence of colorectal cancer (CRC) and endometrial cancer in patients and their relatives was related to mutation prevalence with logistic regression analysis. The performances of simplified and more complex models were quantified with a concordance statistic (c), which was corrected for optimism by cross-validation and bootstrapping. External validation was performed in 1016 patients. The first challenge was the coding of age at diagnosis of CRC, where we forced effects to be identical in patients, in 1st degree and in 2nd degree relatives, by taking the sum of the ages at diagnosis. As a further simplification, CRC diagnosis in 2nd degree relatives was weighted half that of 1st degree relatives. These data reduction approaches were also followed for endometrial cancer. The simplified model used 7 instead of 17 degrees of freedom (df) for a more complex model incorporating individual predictor effects. The optimism-corrected c was higher (0.79 instead of 0.77), but the external c was similar (0.78 for the simplified and more complex models). A stepwise selected model performed slightly worse (external c=0.77). In conclusion, a prediction model could be developed with relatively few df that captured effects of age at diagnosis across patients and relatives per type of cancer in the family. Such robust coding may especially be relevant for modeling in relatively small data sets. Copyright (c) 2007 John Wiley & Sons, Ltd.

  6. Quantitative morphologic analysis of boulder shape and surface texture to infer environmental history: A case study of rock breakdown at the Ephrata Fan, Channeled Scabland, Washington

    NASA Astrophysics Data System (ADS)

    Ehlmann, Bethany L.; Viles, Heather A.; Bourke, Mary C.

    2008-05-01

    Boulder morphology reflects both lithology and climate and is dictated by the combined effects of erosion, transport, and weathering. At present, morphologic information at the boulder scale is underutilized as a recorder of environmental processes, partly because of the lack of a systematic quantitative parameter set for reporting and comparing data sets. We develop such a parameter set, incorporating a range of measures of boulder form and surface texture. We use standard shape metrics measured in the field and fractal and morphometric classification methods borrowed from landscape analysis and applied to laser-scanned molds. The parameter set was pilot tested on three populations of basalt boulders with distinct breakdown histories in the Channeled Scabland, Washington: (1) basalt outcrop talus; (2) flood-transported boulders recently excavated from a quarry; and (3) flood-transported boulders, extensively weathered in situ on the Ephrata Fan surface. Size and shape data were found to distinguish between flood-transported and untransported boulders. Size and edge angles (~120°) of flood-transported boulders suggest removal by preferential fracturing along preexisting columnar joints, and curvature data indicate rounding relative to outcrop boulders. Surface textural data show that boulders which have been exposed at the surface are significantly rougher than those buried by fan sediments. Past signatures diagnostic of flood transport still persist on surface boulders, despite ongoing overprinting by processes in the present breakdown environment through roughening and fracturing in situ. Further use of this quantitative boulder parameter set at other terrestrial and planetary sites will aid in cataloging and understanding morphologic signatures of environmental processes.

  7. Quantitative Morphologic Analysis of Boulder Shape and Surface Texture to Infer Environmental History: A Case Study of Rock Breakdown at the Ephrata Fan, Channeled Scabland, Washington

    NASA Technical Reports Server (NTRS)

    Ehlmann, Bethany L.; Viles, Heather A.; Bourke, Mary C.

    2008-01-01

    Boulder morphology reflects both lithology and climate and is dictated by the combined effects of erosion, transport, and weathering. At present, morphologic information at the boulder scale is underutilized as a recorder of environmental processes, partly because of the lack of a systematic quantitative parameter set for reporting and comparing data sets. We develop such a parameter set, incorporating a range of measures of boulder form and surface texture. We use standard shape metrics measured in the field and fractal and morphometric classification methods borrowed from landscape analysis and applied to laser-scanned molds. The parameter set was pilot tested on three populations of basalt boulders with distinct breakdown histories in the Channeled Scabland, Washington: (1) basalt outcrop talus; (2) flood-transported boulders recently excavated from a quarry; and (3) flood-transported boulders, extensively weathered in situ on the Ephrata Fan surface. Size and shape data were found to distinguish between flood-transported and untransported boulders. Size and edge angles (approximately 120 degrees) of flood-transported boulders suggest removal by preferential fracturing along preexisting columnar joints, and curvature data indicate rounding relative to outcrop boulders. Surface textural data show that boulders which have been exposed at the surface are significantly rougher than those buried by fan sediments. Past signatures diagnostic of flood transport still persist on surface boulders, despite ongoing overprinting by processes in the present breakdown environment through roughening and fracturing in situ. Further use of this quantitative boulder parameter set at other terrestrial and planetary sites will aid in cataloging and understanding morphologic signatures of environmental processes.

  8. Termination: A Case Study.

    PubMed

    Friedberg, Ahron L

    2015-12-01

    In this article I posit and examine certain criteria and qualities for ending an analysis. The case study describes the end phase of a four-year psychoanalysis in which the patient's decision to move to another area forced the end of his analysis. We continued to explore and work through his core neurotic conflicts that included issues of competitive rivalry, dominance and submission, control, and anxiety about birth and death. A shift in the transference from me as a negative father to me as a supportive but competitive older brother was also examined in the context of ending treatment as well as other aspects of the transference. In addition, we analyzed the meaning of his ending treatment based on an extra-analytic circumstance. In discussing this phase of treatment, the definition and history of the term "termination" and its connotations are reviewed. Various criteria for completing an analysis are examined, and technical observations about this phase of treatment are investigated. It was found that while a significant shift in the transference occurred in this phase of the patient's analysis, conflicts related to the transference were not "resolved" in the classical sense. Terminating treatment was considered as a practical matter in which the patient's autonomy and sense of choice were respected and analyzed.

  9. Electrical leak detection system for landfill liners: A case history

    SciTech Connect

    White, C.C.; Barker, R.D.

    1997-12-01

    As landfill specifications become more stringent in the United Kingdom, the development of increasingly sophisticated monitoring methods is necessary to meet environmental protection goals. The case history describes the development of a 2-million-cubic-meter-capacity landfill, located in a sandstone quarry and 1 km from a public water supply borehole, where the sensitivity of the site to ground water contamination and the proximity to a public water supply borehole are particular issues. The landfill design incorporated a more sensitive environmental monitoring system, using a geophysical technique. The monitoring system comprises a permanent grid of electrodes installed beneath the landfill, connected by multicore cable to a computer-controlled earth resistance meter and switching unit in the site weighbridge. It was designed to detect holes in the landfill liner prior to and after covering with waste and to monitor the migration of contaminants beneath the landfill before they reach the perimeter observation boreholes, should leakage occur.

  10. Case study research.

    PubMed

    Taylor, Ruth; Thomas-Gregory, Annette

    2015-06-10

    This article describes case study research for nursing and healthcare practice. Case study research offers the researcher an approach by which a phenomenon can be investigated from multiple perspectives within a bounded context, allowing the researcher to provide a 'thick' description of the phenomenon. Although case study research is a flexible approach for the investigation of complex nursing and healthcare issues, it has methodological challenges, often associated with the multiple methods used in individual studies. These are explored through examples of case study research carried out in practice and education settings. An overview of what constitutes 'good' case study research is proposed.

  11. [New studies on the history of anesthesiology (1)--A newly discovered truth on Woolley and Roe case after an interval of 50 years].

    PubMed

    Matsuki, A

    2000-06-01

    A famous medical accident that is widely known as Woolley and Roe case occurred on Oct 13th, 1947 at the Chesterfield Royal Hospital, England. The patients Albert Woolley and Cecil Roe underwent minor operations under spinal anesthesia using cinchocaine to develop spinal cord myelopathy with paralisis of bilateral legs. Both patients sued Dr James M. Graham, the anesthetist, and the Ministry of Health. Seven years later, Dr Graham and the Ministry of Health were given a verdict of not guilty, because three judges unanimously accepted the phenol theory proposed by a witness Prof Macintosh of Oxford University. He allged that phenol entered into the ampoule of cinchocaine through invisible cracks. Thus the plaintiffs were not compensated. Recentry Dr Hutter of Nottingham University found no validity of phenol theory and also no possibility of invisible cracks. Syringes and needles for spinal anesthesia were used to be sterilised by water-boiling steriliser, and mineral acid was used for descaling the deposition of line at that time. Dr Hutter concluded that the severe spinal myelopathy occurred both in Woolley and Roe would have been caused by mineral acid which was conveyed into their subarachnoidal space by acid-contaminated syringes and needles.

  12. Measuring History: Cases of State-Level Testing across the United States. Research in Curriculum and Instruction

    ERIC Educational Resources Information Center

    Grant, S. G., Ed.

    2006-01-01

    Measuring History complements the cases presented in Wise Social Studies Practices (Yeager & Davis, 2005). Yeager and Davis highlight the rich and ambitious teaching that can occur in the broad context of state-level testing. In this book, the chapter authors and I bring the particular state history tests more to the fore and examine how…

  13. Measuring History: Cases of State-Level Testing across the United States. Research in Curriculum and Instruction

    ERIC Educational Resources Information Center

    Grant, S. G., Ed.

    2006-01-01

    Measuring History complements the cases presented in Wise Social Studies Practices (Yeager & Davis, 2005). Yeager and Davis highlight the rich and ambitious teaching that can occur in the broad context of state-level testing. In this book, the chapter authors and I bring the particular state history tests more to the fore and examine how…

  14. Family history of cancer, personal history of medical conditions and risk of oral cavity cancer in France: the ICARE study

    PubMed Central

    2013-01-01

    Background The aim of this study was to evaluate the role of family history of cancer and personal history of other medical conditions in the aetiology of the oral cavity cancer in France. Methods We used data from 689 cases of oral cavity squamous cell carcinoma and 3481 controls included in a population-based case–control study, the ICARE study. Odds-ratios (ORs) associated with family history of cancer and personal medical conditions and their 95% confidence intervals (95% CI) were estimated by unconditional logistic regression and were adjusted for age, gender, area of residence, education, body mass index, tobacco smoking and alcohol drinking. Results Personal history of oral candidiasis was related to a significantly increased risk of oral cavity cancer (OR 5.0, 95% CI 2.1-12.1). History of head and neck cancers among the first-degree relatives was associated with an OR of 1.9 (95% CI 1.2-2.8). The risk increased with the number of first-degree relatives with head and neck cancer. Conclusion A family history of head and neck cancer is a marker of an increased risk of oral cavity cancer and should be taken into account to target prevention efforts and screening. Further studies are needed to clarify the association between oral cavity cancer and personal history of candidiasis. PMID:24286495

  15. The Examination of Patient-Reported Outcomes and Postural Control Measures in Patients with and without a History of ACL Reconstruction: a Case Control Study.

    PubMed

    Hoch, Johanna M; Sinnott, Cori W; Robinson, Kendall P; Perkins, William O; Hartman, Jonathan W

    2017-03-02

    There is a lack of literature to support the diagnostic accuracy and cut-off scores of commonly used patient-reported outcome measures (PROMs) and clinician-oriented outcomes such as postural-control assessments (PCAs) when treating post-ACL reconstruction (ACLR) patients. These scores could help tailor treatments, enhance patient-centered care and may identify individuals in need of additional rehabilitation. To determine if differences in 4-PROMs and 3-PCAs exist between post-ACLR and healthy participants, and to determine the diagnostic accuracy and cut-off scores of these outcomes. Case-control. Laboratory. A total of 20 post-ACLR and 40 healthy control participants. The participants completed 4-PROMs: the Disablement in the Physically Active Scale (DPA), The Fear-Avoidance Belief Questionnaire (FABQ), the Knee Osteoarthritis Outcomes Score (KOOS) subscales, and the Tampa Scale of Kinesiophobia (TSK-11) and 3-PCAs: the Balance Error Scoring System (BESS), the modified Star Excursion Balance Test (SEBT) and static balance on an instrumented force plate. Mann-Whitney U tests examined differences between groups. Receiver operating characteristic (ROC) curves were employed to determine sensitivity and specificity. The Area Under the Curve (AUC) was calculated to determine the diagnostic accuracy of each instrument. The Youdin Index was used to determine cut-off scores. Alpha was set a priori at p<0.05. There were significant differences between groups for all PROMs (p<0.05). There were no differences in PCAs between groups. The cut-off scores should be interpreted with caution for some instruments, as the scores may not be clinically applicable. Post-ACLR participants have decreased self-reported function and health-related quality of life. The PROMs are capable of discriminating between groups. Clinicians should consider using the cut-off scores in clinical practice. Further use of the instruments to examine detriments after completion of standard rehabilitation

  16. [History of studies of alcohol toxicology].

    PubMed

    Konopka, Tomasz

    2010-01-01

    The early history of forensic alcohology was presented, based on writings from the beginning of the 20th century and numerous forensic medical protocols from autopsies performed in Institute of Forensic Medicine in Cracow in the 19th and 20th century. Ethanol has not been considered a poison for a long time. Suspicion of its toxic effect resulted from cases of deaths as a results of people betting who can drink more alcohol. In case of alcohol poisoning, autopsy does not show any typical changes, so the poisonings have not been recognized for many years. At the beginning of the 20th century, the first chemical tests appeared. They were able to detect the presence of alcohol in tissues. A method for measuring the amount of alcohol in blood was also developed. The majority of methods were based on distillation of blood and inspection of the resultant distillate by physical methods (interferometry, colorimetry, refractometry, gravimetry, measuring thermal expansion and electrical conduction) or chemical methods using different reactions (oxidation of alcohol to acetic acid, reducing potassium dichromate by alcohol, alkylation of iodine by alcohol) and marking the amount of products of reaction by titration. Distillation of blood samples required complicated chemical devices and was very time consuming. Erik Widmark suggested a certain method in 1920, in which distillation of a blood sample took place in the same container, in which titration was performed earlier--the so-called Widmark's Flask. It allowed for distilling many samples in an incubator at the same time and dramatically shortened the time of research. Widmark's method was applied to testing drivers and people who committed crimes and was used in the whole world for many following years.

  17. Oral cavity rare lesions: 15 years case histories

    PubMed Central

    BARTULI, F.N.; LUCIANI, F.; CARDONI, G.; MUZZI, F.; CADDEO, F.; OTTRIA, L.; ARCURI, C.

    2011-01-01

    SUMMARY Objectives. Oral cavity rare diseases include a various group of uncommon morbid conditions. For this reason they are often called “orphan diseases”, as they are not interesting for research and the description of their natural history is not easy. The aim of our study is to analyze the prevalence and the distribution of oral cavity rare diseases in order to increase their knowledge and allow a fast therapeutic approach. Methods and material. 3144 patients took part to our study, they were choosen according to specific criteria and included in a experimental program; they all were prepared for oral biopsy surgery at Fatebenefratelli Hospital - Tor Vergata University of Rome. Following the results of the histological diagnosis, patients have been grouped. Results. From 1996 to 2010, we observed 1635 men and 1509 women, average age was 53 years, higher for women (55y.) and lower for men (52y.). Conclusions. Nevertheless the low level of accordance and the difficulty in description of natural history of diseases reported in literature, we can conclude that, according to our study the onset of rare diseases shows a percentage of appearing statistically significant. PMID:23277869

  18. Growth and resilience of pioneering nonprofit human service organizations: a cross-case analysis of organizational histories.

    PubMed

    Kimberlin, Sara E; Schwartz, Sara L; Austin, Michael J

    2011-01-01

    Knowledge of organizational history is important for recognizing patterns in effective management and understanding how organizations respond to internal and external challenges. This cross-case analysis of 12 histories of pioneering nonprofit human service organizations contributes an important longitudinal perspective on organizational history, complementing the cross-sectional case studies that dominate the existing research on nonprofit organizations. The literature on organizational growth, including lifecycle models and growth management, is reviewed, along with the literature on organizational resilience. Based on analysis of the 12 organizational histories, a conceptual model is presented that synthesizes key factors in the areas of leadership, internal operations, and external relations that influence organizational growth and resilience to enable nonprofit organizations to survive and thrive over time. Both cross-sectional and longitudinal examples from the organizational histories illustrate the conceptual map. The paper concludes with a discussion of directions for future research on nonprofit organizational history.

  19. Graeco-Roman case histories and their influence on Medieval Islamic clinical accounts.

    PubMed

    Alvarez Millan, C

    1999-04-01

    The medieval Islamic medical tradition was the direct heir of Classical and Hellenistic medicine thanks to an unprecedented movement of translation into Arabic, commentaries and systematizations of Greek scientific texts. In the process of assimilation, not only theoretical principles, but also literary models of presenting medical knowledge were adopted, amongst them the case history. Since the clinical account can be used as a tool for medical instruction as well as an instrument for professional self-promotion, this study seeks to investigate which purpose most motivated Islamic physicians, and to demonstrate the extent to which they were influenced by the stylistic patterns which served them as a model. This article comprises an analysis of the context, literary devices and purpose of case histories of the Epidemics, Rufus of Ephesos and Galen, and compares them with those by the tenth-century Islamic physician Abu Bakr Muhammad b. Zakariya al-Razi. Author of the largest number of case histories preserved within the medieval Islamic medical literature, al-Razi's clinical records constitute an instrument with which to study and expand medical knowledge as well as providing useful material for students' medical training. Although al-Razi fused elements from the sources which served him as a model, he did not emulate Galen's use of the clinical history to assert himself in order to gain authority and prestige, but remained faithful to the Hippocratic essence.

  20. Historical Literacy: The Case for History in American Education.

    ERIC Educational Resources Information Center

    Gagnon, Paul, Ed.

    The Bradley Commission on History in Schools was created in 1987 specifically in response to the widespread concern over the inadequacy, both in quantity and in quality, of the history taught in elementary and secondary school classrooms. This book explores the conditions that contribute to, or impede, the effective teaching of history in schools.…

  1. Using History to Teach Mathematics: The Case of Logarithms

    ERIC Educational Resources Information Center

    Panagiotou, Evangelos N.

    2011-01-01

    Many authors have discussed the question "why" we should use the history of mathematics to mathematics education. For example, Fauvel ("For Learn Math," 11(2): 3-6, 1991) mentions at least fifteen arguments for applying the history of mathematics in teaching and learning mathematics. Knowing "how" to introduce history into mathematics lessons is a…

  2. Using History to Teach Mathematics: The Case of Logarithms

    ERIC Educational Resources Information Center

    Panagiotou, Evangelos N.

    2011-01-01

    Many authors have discussed the question "why" we should use the history of mathematics to mathematics education. For example, Fauvel ("For Learn Math," 11(2): 3-6, 1991) mentions at least fifteen arguments for applying the history of mathematics in teaching and learning mathematics. Knowing "how" to introduce history into mathematics lessons is a…

  3. Historical Literacy: The Case for History in American Education.

    ERIC Educational Resources Information Center

    Gagnon, Paul, Ed.

    The Bradley Commission on History in Schools was created in 1987 specifically in response to the widespread concern over the inadequacy, both in quantity and in quality, of the history taught in elementary and secondary school classrooms. This book explores the conditions that contribute to, or impede, the effective teaching of history in schools.…

  4. Warfarin monitoring in nursing homes assessed by case histories. Do recommendations and electronic alerts affect judgements?

    PubMed

    Teruel, Reyes Serrano; Thue, Geir; Fylkesnes, Svein Ivar; Sandberg, Sverre; Kristoffersen, Ann Helen

    2017-09-01

    Older adults treated with warfarin are prone to complications, and high-quality monitoring is essential. The aim of this case history based study was to assess the quality of warfarin monitoring in a routine situation, and in a situation with an antibiotic-warfarin interaction, before and after receiving an electronic alert. In April 2014, a national web-based survey with two case histories was distributed among Norwegian nursing home physicians and general practitioners working part-time in nursing homes. Case A represented a patient on stable warfarin treatment, but with a substantial INR increase within the therapeutic interval. Case B represented a more challenging patient with trimethoprim sulfamethoxazole (TMS) treatment due to pyelonephritis. In both cases, the physicians were asked to state the next warfarin dose and the INR recall interval. In case B, the physicians could change their suggestions after receiving an electronic alert on the TMS-warfarin interaction. Three hundred and ninety eight physicians in 292 nursing homes responded. Suggested INR recall intervals and warfarin doses varied substantially in both cases. In case A, 61% gave acceptable answers according to published recommendations, while only 9% did so for case B. Regarding the TMS-warfarin interaction in case history B, the electronic alert increased the percentage of respondents correctly suggesting a dose reduction from 29% to 53%. Having an INR instrument in the nursing home was associated with shortened INR recall times. Practical advice on handling of warfarin treatment and drug interactions is needed. Electronic alerts as presented in electronic medical records seem insufficient to change practice. Availability of INR instruments may be important regarding recall time.

  5. A history of the working group to address Los Alamos community health concerns - A case study of community involvement and risk communication

    SciTech Connect

    Harry Otway; Jon Johnson

    2000-01-01

    In May 1991, at a Department of Energy (DOE) public hearing at Los Alamos, New Mexico, a local artist claimed there had been a recent brain tumor cluster in a small Los Alamos neighborhood. He suggested the cause was radiation from past operations of Los Alamos National Laboratory. Data from the Laboratory's extensive environmental monitoring program gave no reason to believe this charge to be true but also could not prove it false. These allegations, reported in the local and regional media, alarmed the community and revealed an unsuspected lack of trust in the Laboratory. Having no immediate and definitive response, the Laboratory offered to collaborate with the community to address this concern. The Los Alamos community accepted this offer and a joint Community-Laboratory Working Group met for the first time 29 days later. The working group set as its primary goal the search for possible carcinogens in the local environment. Meanwhile, the DOE announced its intention to fund the New Mexico Department of Health to perform a separate and independent epidemiological study of all Los Alamos cancer rates. In early 1994, after commissioning 17 environmental studies and meeting 34 times, the working group decided that the public health concerns had been resolved to the satisfaction of the community and voted to disband. This paper tells the story of the artist and the working group, and how the media covered their story. It summarizes the environmental studies directed by the working group and briefly reviews the main findings of the epidemiology study. An epilogue records the present-day recollections of some of the key players in this environmental drama.

  6. Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study.

    PubMed

    Milne, Roger L; Gaudet, Mia M; Spurdle, Amanda B; Fasching, Peter A; Couch, Fergus J; Benítez, Javier; Arias Pérez, José Ignacio; Zamora, M Pilar; Malats, Núria; Dos Santos Silva, Isabel; Gibson, Lorna J; Fletcher, Olivia; Johnson, Nichola; Anton-Culver, Hoda; Ziogas, Argyrios; Figueroa, Jonine; Brinton, Louise; Sherman, Mark E; Lissowska, Jolanta; Hopper, John L; Dite, Gillian S; Apicella, Carmel; Southey, Melissa C; Sigurdson, Alice J; Linet, Martha S; Schonfeld, Sara J; Freedman, D Michal; Mannermaa, Arto; Kosma, Veli-Matti; Kataja, Vesa; Auvinen, Päivi; Andrulis, Irene L; Glendon, Gord; Knight, Julia A; Weerasooriya, Nayana; Cox, Angela; Reed, Malcolm Wr; Cross, Simon S; Dunning, Alison M; Ahmed, Shahana; Shah, Mitul; Brauch, Hiltrud; Ko, Yon-Dschun; Brüning, Thomas; Lambrechts, Diether; Reumers, Joke; Smeets, Ann; Wang-Gohrke, Shan; Hall, Per; Czene, Kamila; Liu, Jianjun; Irwanto, Astrid K; Chenevix-Trench, Georgia; Holland, Helene; Giles, Graham G; Baglietto, Laura; Severi, Gianluca; Bojensen, Stig E; Nordestgaard, Børge G; Flyger, Henrik; John, Esther M; West, Dee W; Whittemore, Alice S; Vachon, Celine; Olson, Janet E; Fredericksen, Zachary; Kosel, Matthew; Hein, Rebecca; Vrieling, Alina; Flesch-Janys, Dieter; Heinz, Judith; Beckmann, Matthias W; Heusinger, Katharina; Ekici, Arif B; Haeberle, Lothar; Humphreys, Manjeet K; Morrison, Jonathan; Easton, Doug F; Pharoah, Paul D; García-Closas, Montserrat; Goode, Ellen L; Chang-Claude, Jenny

    2010-01-01

    Several common breast cancer genetic susceptibility variants have recently been identified. We aimed to determine how these variants combine with a subset of other known risk factors to influence breast cancer risk in white women of European ancestry using case-control studies participating in the Breast Cancer Association Consortium. We evaluated two-way interactions between each of age at menarche, ever having had a live birth, number of live births, age at first birth and body mass index (BMI) and each of 12 single nucleotide polymorphisms (SNPs) (10q26-rs2981582 (FGFR2), 8q24-rs13281615, 11p15-rs3817198 (LSP1), 5q11-rs889312 (MAP3K1), 16q12-rs3803662 (TOX3), 2q35-rs13387042, 5p12-rs10941679 (MRPS30), 17q23-rs6504950 (COX11), 3p24-rs4973768 (SLC4A7), CASP8-rs17468277, TGFB1-rs1982073 and ESR1-rs3020314). Interactions were tested for by fitting logistic regression models including per-allele and linear trend main effects for SNPs and risk factors, respectively, and single-parameter interaction terms for linear departure from independent multiplicative effects. These analyses were applied to data for up to 26,349 invasive breast cancer cases and up to 32,208 controls from 21 case-control studies. No statistical evidence of interaction was observed beyond that expected by chance. Analyses were repeated using data from 11 population-based studies, and results were very similar. The relative risks for breast cancer associated with the common susceptibility variants identified to date do not appear to vary across women with different reproductive histories or body mass index (BMI). The assumption of multiplicative combined effects for these established genetic and other risk factors in risk prediction models appears justified.

  7. Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

    PubMed Central

    2010-01-01

    Introduction Several common breast cancer genetic susceptibility variants have recently been identified. We aimed to determine how these variants combine with a subset of other known risk factors to influence breast cancer risk in white women of European ancestry using case-control studies participating in the Breast Cancer Association Consortium. Methods We evaluated two-way interactions between each of age at menarche, ever having had a live birth, number of live births, age at first birth and body mass index (BMI) and each of 12 single nucleotide polymorphisms (SNPs) (10q26-rs2981582 (FGFR2), 8q24-rs13281615, 11p15-rs3817198 (LSP1), 5q11-rs889312 (MAP3K1), 16q12-rs3803662 (TOX3), 2q35-rs13387042, 5p12-rs10941679 (MRPS30), 17q23-rs6504950 (COX11), 3p24-rs4973768 (SLC4A7), CASP8-rs17468277, TGFB1-rs1982073 and ESR1-rs3020314). Interactions were tested for by fitting logistic regression models including per-allele and linear trend main effects for SNPs and risk factors, respectively, and single-parameter interaction terms for linear departure from independent multiplicative effects. Results These analyses were applied to data for up to 26,349 invasive breast cancer cases and up to 32,208 controls from 21 case-control studies. No statistical evidence of interaction was observed beyond that expected by chance. Analyses were repeated using data from 11 population-based studies, and results were very similar. Conclusions The relative risks for breast cancer associated with the common susceptibility variants identified to date do not appear to vary across women with different reproductive histories or body mass index (BMI). The assumption of multiplicative combined effects for these established genetic and other risk factors in risk prediction models appears justified. PMID:21194473

  8. Three 20th-century multiauthored handbooks serving as vital catalyzers of an emerging specialization: a case study from the history of neurology and psychiatry.

    PubMed

    Stahnisch, Frank W; Koehler, Peter J

    2012-12-01

    Originating in the late 19th century, psychiatry and neurology emerged during a period of several decades as two distinct fields of medical inquiry, separate from the study and practice of internal medicine. Around 1900, the German-speaking countries in Europe played an important role in this development. In this article, the publication of three influential multivolume and multiauthor handbooks are studied. All available volumes of Max Lewandowsky's Handbuch der Neurologie (1910-1914) and the Handbuch der Neurologie (1935-1937) of Oswald Bumke and Otfrid Foerster are analyzed. The handbooks are compared with Pierre Vinken and George Bruyn's Handbook of Clinical Neurology (1968-2002). This article is particularly timely in that it helps to reveal some of the origins of the disciplinary split-even at a moment when "brain psychiatry" (Wilhelm Griesinger), "neuropsychiatry" (Kurt Goldstein), and the German notion of Nervenheilkunde all acknowledged the interdisciplinary nature of both psychiatry and neurology. Particular emphasis is placed on the preeminent role that Jewish clinical neurologists assumed in the editing of the respective handbooks, leading to the extraordinary breadth and wealth of these publications. A great number of doyens in the fields of neurology and psychiatry-among them numerous Nobel Prize laureates-were involved in the dissemination of contemporary knowledge, including diagnostic and therapeutic procedures, which testifies to the fundamental status that these handbooks held for training purposes for both undergraduate and postgraduate students. Finally, the volumes analyzed in this article (between 1911 and 2002) are representative of a shift in the dominant scientific language, from German to English, since the 1930s and the 1940s, as well as the change in geographical distribution of the leading scientific authors, from Central Europe (Germany, Austria, Holland, France, Italy, and Scandinavia) to North America (the United States).

  9. Is a positive family history predictive for recurrent acute otitis media in children? An evidence-based case report.

    PubMed

    Albersen, Monique; Bulatović, Maja; Lindner, Sanneke H; van Stiphout, Feikje; van der Heijden, Geert J M G; Schilder, Anne G M; Rovers, Maroeska M

    2010-01-01

    In this evidence-based case report, we studied the clinical question: Is a positive family history of acute otitis media (AOM) predictive for recurrent acute otitis media (rAOM) in children between zero and two years of age? The search yielded 3178 articles, of which only two were relevant and had a high validity regarding our clinical question. Neither of these two studies provided the final answer to our clinical question because they did not report stratified absolute risks for a positive family history. Fortunately, we were able to study the absolute risks in one of the two studies. The absolute risk of rAOM without distinguishing family history was 33 percent; the risk was 27 percent for children without a family history and 45 percent for children with a positive family history. Family history increases the absolute risk, but not in a way that it will help to predict rAOM accurately.

  10. The history of Belgian assisted reproduction technology cycle registration and control: a case study in reducing the incidence of multiple pregnancy.

    PubMed

    De Neubourg, D; Bogaerts, K; Wyns, C; Albert, A; Camus, M; Candeur, M; Degueldre, M; Delbaere, A; Delvigne, A; De Sutter, P; Dhont, M; Dubois, M; Englert, Y; Gillain, N; Gordts, S; Hautecoeur, W; Lesaffre, E; Lejeune, B; Leroy, F; Ombelet, W; Perrier D'Hauterive, S; Vandekerckhove, F; Van der Elst, J; D'Hooghe, T

    2013-10-01

    What is the effect of a legal limitation of the number of embryos that can be transferred in an assisted reproductive technology (ART) cycle on the multiple delivery rate? The Belgian national register shows that the introduction of reimbursement of ART laboratory costs in July 2003, and the imposition of a legal limitation of the number of embryos transferred in the same year, were associated with a >50% reduction of the multiple pregnancy rate from 27 to 11% between 2003 and the last assessment in 2010, without any reduction of the pregnancy rate per cycle. Individual Belgian IVF centres have published their results since the implementation of the law, and these show a decrease in the multiple pregnancy rate on a centre by centre basis. However, the overall national picture remains unpublished. Cohort study from 1990 to 2010 of all ART cycles in Belgium (2685 cycles in 1990 evolving to 19 110 cycles in 2010), with a retrospective analysis from 1990 to 2000 and prospective online data collection since 2001. Registration evolved from paper written reports per centre to a compulsory online registration of all ART cycles. From 2001 up to mid-2009, data were collected from Excel spread sheets or MS Access files into an MS Access database. Since mid-2009, data collection is done via a remote and secured web-based system (www.belrap.be) where centres can upload their data and get immediate feedback about missing data, errors and inconsistencies. National Belgian registration data show that reimbursement of IVF laboratory costs in July 2003, coupled to a legal limitation in the number of embryos transferred in utero, were associated with a 50% reduction of the multiple pregnancy rate from 27 to 11% without reduction of the pregnancy rate per cycle, and with an increase in the number of fresh and frozen ART cycles due to improved access to treatment. There is potential underreporting of complications of ART treatment, pregnancy outcome and neonatal health. Over the 20

  11. Interpreting the paleozoogeography and sea level history of thermally anomalous marine terrace faunas: a case study from the the Last Interglacial Complex of San Clemente Island, California

    USGS Publications Warehouse

    Muhs, Daniel R.; Groves, Lindsey T.; Schumann, R. Randall

    2014-01-01

    Marine invertebrate faunas with mixtures of extralimital southern and extralimital northern faunal elements, called thermally anomalous faunas, have been recognized for more than a century in the Quaternary marine terrace record of the Pacific Coast of North America. Although many mechanisms have been proposed to explain this phenomenon, no single explanation seems to be applicable to all localities where thermally anomalous faunas have been observed. Here, we describe one such thermally anomalous fossil fauna that was studied on the second emergent marine terrace at Eel Point on San Clemente Island. The Eel Point terrace complex is a composite feature, consisting of a narrow upper bench (terrace 2a) and a broader lower bench (terrace 2b). Terrace 2b, previously dated from ~128 ka to ~114 ka, was thought to date solely to marine isotope stage (MIS) 5.5, representing the peak of the last interglacial period. Nevertheless, the fauna contains an extralimital northern species and several northward-ranging species, as well as an extralimital southern species and several southward-ranging species. Similar faunas with thermally anomalous elements have also been reported from San Nicolas Island, Point Loma (San Diego County), and Cayucos (San Luis Obispo County), California. U-series dating of corals at those localities shows that the thermally anomalous faunas may be the result of mixing of fossils from both the ~100-ka (cool-water) and the ~120-ka (warm-water) sea level high stands. Submergence, erosion, and fossil mixing of the ~120-ka terraces by the ~100-ka high-sea stand may have been possible due to glacial isostatic adjustment (GIA) effects on North America, which could have resulted in a higher-than-present local sea level stand at ~100 ka. The terrace elevation spacing on San Clemente Island is very similar to that on San Nicolas Island, and we hypothesize that a similar mixing took place on San Clemente Island. Existing fossil records from older terraces

  12. On continuity case studies.

    PubMed

    Lindstedt, David; Lombardo, Timothy

    This article is divided into three sections. The first section provides a taxonomy of case studies within the field of business continuity along with a brief commentary. The second section discusses the proper use of case studies in general pedagogy and provides research-based recommendations for their employment. The third section provides suggestions and examples of how business continuity case studies might be utilised specifically for instruction in the discipline of business continuity planning.

  13. Incorrect when uncorrected: Reconstructing vegetation history using n-alkane biomarkers in loess-paleosol sequences - a case study from the Saxonian loess region, Germany

    NASA Astrophysics Data System (ADS)

    Zech, M.; Krause, T.; Meszner, S.; Faust, D.

    2012-04-01

    With our study (Zech et al., Quaternary International, accepted) we aim at contributing to the reconstruction of the paleoenvironment of the Saxonian loess region by investigating sedimentary n-alkanes as plant leafwax derived biomarkers in two loess-paleosol sequences (LPSs), namely the Gleina and the Rottewitz LPSs. The Weichselian paleosols are characterised by n-alkane concentration maxima when compared to the loess layers. When this coincides with high odd-over-even predominances (OEPs), this points not only to increased n-alkane input and/or production but also to increased n-alkane preservation in the soils, namely in gleysols with water-logged edaphic conditions. By contrast, the buried cambisols reveal low OEPs, indicating accelerated degradation under aerobic edaphic conditions. The n-alkane concentrations in the truncated Eemian Interglacial paleosol are very low. This reflects the removal of the formerly n-alkane-enriched Eemian topsoil, low n-alkane input into the Bt-Sd-horizon (subsoil horizon of the Eemian luvisol) and/or strong soil organic matter mineralization. Four investigated n-alkane ratios show distinct variations during the Weichselian tempting to infer vegetation changes in terms of varying contributions of tree/shrub-derived (dominated by nC27 or nC29) versus grass-derived (dominated by nC31 or nC33) n-alkanes. However, using the OEP as a proxy for degradation and considering that n-alkane ratios are prone to degradation effects, we highlight that the above interpretation is very likely incorrect. Indeed, degradation can be accounted for most variability of the n-alkane ratios. Applying an endmember model based on a modern n-alkane reference dataset allows estimating the contribution of tree/shrub- versus grass-derived n-alkanes semi-quantitatively. These modelling results suggest that both the Gleina and the Rottewitz LPSs were formed under prevailing grassland. Minor contributions of trees/shrubs are only likely for the Gleinaer Soil

  14. Progressive hemifacial atrophy. A natural history study.

    PubMed Central

    Miller, M T; Spencer, M A

    1995-01-01

    PURPOSE: To describe two very different natural history courses in 2 patients with hemifacial atrophy. Progressive hemifacial atrophy (Parry-Romberg syndrome, Romberg syndrome, PHA) is characterized by slowly progressive atrophy, frequently involving only one side of the face, primarily affecting the subcutaneous tissue and fat. The onset usually occurs during the first 2 decades of life. The cause and pathophysiology are unknown. Ophthalmic involvement is common, with progressive enophthalmos a frequent finding. Pupillary disturbances, heterochromia, uveitis, pigmentary disturbances of the ocular fundus, and restrictive strabismus have also been reported. Neurologic findings may be present, but the natural history and progression of ocular findings are often not described in the literature. METHODS: We studied the records and present findings of 2 patients with progressive hemifacial atrophy who were observed in our institution over a 10-year period. RESULTS: Both patients showed progression of ophthalmic findings, primarily on the affected side. One patient has had chronic uveitis with secondary cataract and glaucoma, in addition to retinal pigmentary changes. She also had a third-nerve paresis of the contralateral eye and mild seizure activity. The other patient had mild uveitis, some progression of unilateral retinal pigmentary changes, and a significant increase in hyperopia in the affected eye, in addition to hypotony at age 19 without a clear cause, but with secondary retinal and refractive changes. CONCLUSION: Ocular manifestations of progressive hemifacial atrophy are varied, but can progress from mild visual impairment to blindness. Images FIGURE 1 FIGURE 2 FIGURE 3A FIGURE 3B FIGURE 4 FIGURE 5 FIGURE 6 PMID:8719679

  15. Waldorf History: Case Study of Institutional Memory.

    ERIC Educational Resources Information Center

    Oberman, Ida

    This paper asserts that the century-old educational reform movement known as "Waldorf" is an instance of the tremendous potential that semiotic representation holds for school reform. It proposes that Waldorf's staying power is hidden in the reform's semiotic supports: its symbols, motifs, and rituals. Rather than presenting Waldorf's…

  16. Teaching History with Media: A Case Study.

    ERIC Educational Resources Information Center

    Tengwall, David

    Although research has demonstrated that the well-planned use of audio-visual (AV) media enhances student learning, classroom use of media is usually confined to sporadic, individual presentations which serve only as an auxiliary to the lecture and which are too often regarded by the student as entertainment. To realize the potential of AV media…

  17. [A study on medical history and historiography of medicine].

    PubMed

    Wang, Zhen-Rui

    2011-09-01

    Medical history is the objective process of the development of medicine. Medicine historiography is the recording, interpretation and comments of this process. Historiography of medicine is often called medical history. By subject attribute, historiography of medicine belongs to history and could be divided into study on specific medical historiography (the objective ibeing medical history), historical materials on medicine (the objective is to offer reliable materials for specific medical historiography) and study on medical historiography (the objective being mthe historiography of medicine itself).

  18. [Case and studies].

    PubMed

    Schubert, András

    2015-11-15

    Case studies and case reports form an important and ever growing part of scientific and scholarly literature. The paper deals with the share and citation rate of these publication types on different fields of research. In general, evidence seems to support the opinion that an excessive number of such publications may negatively influence the impact factor of the journal. In the literature of scientometrics, case studies (at least the presence of the term "case study" in the titles of the papers) have a moderate share, but their citation rate is practically equal to that of other publication types.

  19. Secular vs. Sacred History: The Case of the World History Chart.

    ERIC Educational Resources Information Center

    Donnelly, F. K.

    1989-01-01

    Evaluates the accuracy and usefulness of "The World History Chart: A Chronology of World History According to R. H. Carling." Claims it presents a narrow, sacred interpretation of certain periods of world chronology representing the unorthodox view of one small religious group, the Mormons. (LS)

  20. SETDA Case Studies 2012

    ERIC Educational Resources Information Center

    State Educational Technology Directors Association, 2012

    2012-01-01

    The State Educational Technology Directors Association (SETDA) published a series of case studies from 28 states to showcase examples of how ARRA EETT ("American Recovery and Reinvestment Act of 2009 Enhancing Education Through Technology") grant funds have impacted teaching and learning. SETDA collected data for the case studies through…

  1. Case Study: Challenging Change.

    ERIC Educational Resources Information Center

    May, Steven K.

    2003-01-01

    Discusses a case study involving organizational change and its effect on employees. Presents three responses to the case study: "Paradox of Ordering Change: I Insist That We Work as a Team" (Paaige K. Turner); "Managing Change Is Managing Meaning" (Greg Hearn and Abraham Ninan); and "The Psychodynamics of an Organizational Change Initiative"…

  2. Work Sharing Case Studies.

    ERIC Educational Resources Information Center

    McCarthy, Maureen E.; And Others

    Designed to provide private sector employers with the practical information necessary to select and then to design and implement work sharing arrangements, this book presents case studies of some 36 work sharing programs. Topics covered in the case studies include the circumstances leading to adoption of the program, details of compensation and…

  3. Case Study: Challenging Change.

    ERIC Educational Resources Information Center

    May, Steven K.

    2003-01-01

    Discusses a case study involving organizational change and its effect on employees. Presents three responses to the case study: "Paradox of Ordering Change: I Insist That We Work as a Team" (Paaige K. Turner); "Managing Change Is Managing Meaning" (Greg Hearn and Abraham Ninan); and "The Psychodynamics of an Organizational Change Initiative"…

  4. The natural history of halo nevi: a retrospective case series.

    PubMed

    Aouthmany, Mouhammad; Weinstein, Mara; Zirwas, Matthew J; Brodell, Robert T

    2012-10-01

    The time period between onset of depigmentation around the halo nevus (HN) to complete resolution of the nevus and halo has not been well studied. We sought to better understand the natural history of the HN. A retrospective chart review of patients with a clinical diagnosis of HN selected from a private practice database (1994-2010) was performed. In all, 52 patients with 80 HN were identified. The current stage of the HN was determined by a follow-up questionnaire and physical examination of 36 patients with 56 HN. Seven HN were excised. Of the remaining 49 HN, 51% (25) demonstrated no change in the halo or nevus after an average of 4.2 years; 14.3% (7) demonstrated partial nevus regression with persistence of the halo after an average of 6.7 years; 4.1% (2) demonstrated complete involution of the nevus with persistent halo depigmentation after an average of 7.7 years; 8.2% (4) demonstrated complete nevus involution with some repigmentation of the halo after an average of 11.8 years; 22.4% (11) demonstrated complete resolution of the nevus with complete repigmentation of the halo after an average of 7.8 years. Some subjects were lost to follow-up. The time of initial HN onset was dependent on patient recall. These results demonstrate that HN typically persist for a decade or longer. A subgroup may progress through stages of involution with a return to normal-appearing skin, but even these lesions persisted for an average of 7.8 years. Education about the prolonged natural history of HN may reassure patients and avoid unnecessary excision. Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  5. Lesson Two: Terra Australis. Australian Studies High School Series. History Unit.

    ERIC Educational Resources Information Center

    Waldron, John

    This lesson, one of four stand-alone lessons that examine Australia as an aspect of world history, points out that Australia's unique geographic characteristics and history serve as a useful case study of key global concepts. The lesson focuses on exploration and control of trade routes during the Age of Discovery. The lesson has two parts. In…

  6. History and Imagination: Reenactments for Elementary Social Studies

    ERIC Educational Resources Information Center

    Morris, Ronald Vaughan

    2012-01-01

    In "History and Imagination," elementary school social studies teachers will learn how to help their students break down the walls of their schools, more personally engage with history, and define democratic citizenship. By collaborating together in meaningful investigations into the past and reenacting history, students will become…

  7. History and Imagination: Reenactments for Elementary Social Studies

    ERIC Educational Resources Information Center

    Morris, Ronald Vaughan

    2012-01-01

    In "History and Imagination," elementary school social studies teachers will learn how to help their students break down the walls of their schools, more personally engage with history, and define democratic citizenship. By collaborating together in meaningful investigations into the past and reenacting history, students will become…

  8. Case-control geographic clustering for residential histories accounting for risk factors and covariates

    PubMed Central

    2006-01-01

    Background Methods for analyzing space-time variation in risk in case-control studies typically ignore residential mobility. We develop an approach for analyzing case-control data for mobile individuals and apply it to study bladder cancer in 11 counties in southeastern Michigan. At this time data collection is incomplete and no inferences should be drawn – we analyze these data to demonstrate the novel methods. Global, local and focused clustering of residential histories for 219 cases and 437 controls is quantified using time-dependent nearest neighbor relationships. Business address histories for 268 industries that release known or suspected bladder cancer carcinogens are analyzed. A logistic model accounting for smoking, gender, age, race and education specifies the probability of being a case, and is incorporated into the cluster randomization procedures. Sensitivity of clustering to definition of the proximity metric is assessed for 1 to 75 k nearest neighbors. Results Global clustering is partly explained by the covariates but remains statistically significant at 12 of the 14 levels of k considered. After accounting for the covariates 26 Local clusters are found in Lapeer, Ingham, Oakland and Jackson counties, with the clusters in Ingham and Oakland counties appearing in 1950 and persisting to the present. Statistically significant focused clusters are found about the business address histories of 22 industries located in Oakland (19 clusters), Ingham (2) and Jackson (1) counties. Clusters in central and southeastern Oakland County appear in the 1930's and persist to the present day. Conclusion These methods provide a systematic approach for evaluating a series of increasingly realistic alternative hypotheses regarding the sources of excess risk. So long as selection of cases and controls is population-based and not geographically biased, these tools can provide insights into geographic risk factors that were not specifically assessed in the case

  9. Case-control geographic clustering for residential histories accounting for risk factors and covariates.

    PubMed

    Jacquez, Geoffrey M; Meliker, Jaymie R; Avruskin, Gillian A; Goovaerts, Pierre; Kaufmann, Andy; Wilson, Mark L; Nriagu, Jerome

    2006-08-03

    Methods for analyzing space-time variation in risk in case-control studies typically ignore residential mobility. We develop an approach for analyzing case-control data for mobile individuals and apply it to study bladder cancer in 11 counties in southeastern Michigan. At this time data collection is incomplete and no inferences should be drawn - we analyze these data to demonstrate the novel methods. Global, local and focused clustering of residential histories for 219 cases and 437 controls is quantified using time-dependent nearest neighbor relationships. Business address histories for 268 industries that release known or suspected bladder cancer carcinogens are analyzed. A logistic model accounting for smoking, gender, age, race and education specifies the probability of being a case, and is incorporated into the cluster randomization procedures. Sensitivity of clustering to definition of the proximity metric is assessed for 1 to 75 k nearest neighbors. Global clustering is partly explained by the covariates but remains statistically significant at 12 of the 14 levels of k considered. After accounting for the covariates 26 Local clusters are found in Lapeer, Ingham, Oakland and Jackson counties, with the clusters in Ingham and Oakland counties appearing in 1950 and persisting to the present. Statistically significant focused clusters are found about the business address histories of 22 industries located in Oakland (19 clusters), Ingham (2) and Jackson (1) counties. Clusters in central and southeastern Oakland County appear in the 1930's and persist to the present day. These methods provide a systematic approach for evaluating a series of increasingly realistic alternative hypotheses regarding the sources of excess risk. So long as selection of cases and controls is population-based and not geographically biased, these tools can provide insights into geographic risk factors that were not specifically assessed in the case-control study design.

  10. New Histories for a New State: A Study of History Textbook Content in Northern Ireland

    ERIC Educational Resources Information Center

    Terra, Luke

    2014-01-01

    This study examined the changing content of history textbooks in Northern Ireland, drawing on a sample of 15 textbooks published from 1968 to 2010. Findings from the content and narrative analysis indicated that following the introduction of the Northern Ireland Curriculum in 1991, history textbooks shifted from a narrative to source-driven…

  11. Energy conservation in the textile industry: 10 case histories

    SciTech Connect

    1982-01-01

    Presented are ten case studies of energy conserving technologies that have been implemented by the textile industry. For each case is given: the name and location of the plant and an employee contact, description of products, energy consumption and costs in years before and after the energy conserving technology was implemented, energy savings since the energy conserving technology was implemented, description of investment decision-making process, and description of any institutional and environmental considerations. Measures included are: tandem preparation line, dyebath reuse, bump-and-run (dyebath temperature drifts for the last 85% of the hold time), foam finishing, wastewater heat recovery, wastewater chlorination and reuse, oven exhaust air counterflow, boiler economizer, wood-fired boiler, and solar industrial process heat. Several other energy conserving technologies that were not studied are briefly summarized. (LEW)

  12. Excessive daydreaming: a case history and discussion of mind wandering and high fantasy proneness.

    PubMed

    Schupak, Cynthia; Rosenthal, Jesse

    2009-03-01

    This case study describes a patient presenting with a long history of excessive daydreaming which has caused her distress but is not incident to any other apparent clinical psychiatric disorders. We have treated this patient for over 10 years, and she has responded favorably to fluvoxamine therapy, stating that it helps to control her daydreaming. Our patient, and other psychotherpists, have brought to our attention other possible cases of excessive daydreaming. We examine the available literature regarding daydreaming, mind wandering, and fantasy proneness relative to current cognitive and neuroanatomical models of executive attention.

  13. Failures in Hybrid Microcircuits During Environmental Testing. History Cases

    NASA Technical Reports Server (NTRS)

    Teverovsky, Alexander

    2008-01-01

    This purpose of this viewgraph presentation is to discuss failures in hermetic hybrids observed at the GSFC PA Lab during environmental stress testing. The cases discussed are: Case I. Substrate metallization failures during Thermal cycling (TC). Case II. Flex lid-induced failure. Case Ill. Hermeticity failures during TC. Case IV. Die metallization cracking during TC. and how many test cycles and parts is necessary? Case V. Wire Bond failures after life test. Case VI. Failures caused by Au/In IMC growth.

  14. Education and Work Councils: Four Case Studies.

    ERIC Educational Resources Information Center

    Prager, Audrey; And Others

    This collection of four case studies represents the conclusion of a two-phase study of a federal program to sponsor education and work councils. Following an outline of the history and concept of education and work councils as well as the findings of a study of such councils, the importance of council collaboration with selected sectors is…

  15. Implementation of a Software Application for Presurgical Case History Review of Frozen Section Pathology Cases.

    PubMed

    Norgan, Andrew P; Okeson, Mathew L; Juskewitch, Justin E; Shah, Kabeer K; Sukov, William R

    2017-01-01

    The frozen section pathology practice at Mayo Clinic in Rochester performs ~20,000 intraoperative consultations a year (~70-80/weekday). To prepare for intraoperative consultations, surgical pathology fellows and residents review the case history, previous pathology, and relevant imaging the day before surgery. Before the work described herein, review of pending surgical pathology cases was a paper-based process requiring handwritten transcription from the electronic health record, a laborious and potentially error prone process. To facilitate more efficient case review, a modular extension of an existing surgical listing software application (Surgical and Procedure Scheduling [SPS]) was developed. The module (SPS-pathology-specific module [PM]) added pathology-specific functionality including recording case notes, prefetching of radiology, pathology, and operative reports from the medical record, flagging infectious cases, and real-time tracking of cases in the operating room. After implementation, users were surveyed about its impact on the surgical pathology practice. There were 16 survey respondents (five staff pathologists and eleven residents or fellows). All trainees (11/11) responded that the application improved an aspect of surgical list review including abstraction from medical records (10/11), identification of possibly infectious cases (7/11), and speed of list preparation (10/11). The average reported time savings in list preparation was 1.4 h/day. Respondents indicated the application improved the speed (11/16), clarity (13/16), and accuracy (10/16) of morning report. During the workday, respondents reported the application improved real-time case review (14/16) and situational awareness of ongoing cases (13/16). A majority of respondents found the SPS-PM improved all preparatory and logistical aspects of the Mayo Clinic frozen section surgical pathology practice. In addition, use of the SPS-PM saved an average of 1.4 h/day for residents and fellows

  16. Implementation of a Software Application for Presurgical Case History Review of Frozen Section Pathology Cases

    PubMed Central

    Norgan, Andrew P.; Okeson, Mathew L.; Juskewitch, Justin E.; Shah, Kabeer K.; Sukov, William R.

    2017-01-01

    Background: The frozen section pathology practice at Mayo Clinic in Rochester performs ~20,000 intraoperative consultations a year (~70–80/weekday). To prepare for intraoperative consultations, surgical pathology fellows and residents review the case history, previous pathology, and relevant imaging the day before surgery. Before the work described herein, review of pending surgical pathology cases was a paper-based process requiring handwritten transcription from the electronic health record, a laborious and potentially error prone process. Methods: To facilitate more efficient case review, a modular extension of an existing surgical listing software application (Surgical and Procedure Scheduling [SPS]) was developed. The module (SPS-pathology-specific module [PM]) added pathology-specific functionality including recording case notes, prefetching of radiology, pathology, and operative reports from the medical record, flagging infectious cases, and real-time tracking of cases in the operating room. After implementation, users were surveyed about its impact on the surgical pathology practice. Results: There were 16 survey respondents (five staff pathologists and eleven residents or fellows). All trainees (11/11) responded that the application improved an aspect of surgical list review including abstraction from medical records (10/11), identification of possibly infectious cases (7/11), and speed of list preparation (10/11). The average reported time savings in list preparation was 1.4 h/day. Respondents indicated the application improved the speed (11/16), clarity (13/16), and accuracy (10/16) of morning report. During the workday, respondents reported the application improved real-time case review (14/16) and situational awareness of ongoing cases (13/16). Conclusions: A majority of respondents found the SPS-PM improved all preparatory and logistical aspects of the Mayo Clinic frozen section surgical pathology practice. In addition, use of the SPS-PM saved an

  17. History of Science and Instructional Design: The Case of Electromagnetism.

    ERIC Educational Resources Information Center

    Seroglou, Fanny; Koumaras, Panagiotis; Tselfes, Vassilis

    1998-01-01

    Addresses two research questions pertaining to the search for students' potential alternate conceptions within the history of science and the possibility of helping students overcome these misconceptions through historical experiments. Contains 19 references. (DDR)

  18. Septic Systems Case Studies

    EPA Pesticide Factsheets

    A collection of septic systems case studies to help community planners, elected officials, health department staff, state officials, and interested citizens explore alternatives for managing their decentralized wastewater treatment systems.

  19. HYDROGEOLOGIC CASE STUDIES

    EPA Science Inventory

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  20. MULTIPLE CONTAMINANTS CASE STUDIES

    EPA Science Inventory

    The presentation provides information taken from the arsenic demonstration program projects that have treatment systems removing multiply contaminants from drinking water. The case studies sited in the presentation consist of projects that have arsenic along with either nitrate, ...

  1. MULTIPLE CONTAMINANTS CASE STUDIES

    EPA Science Inventory

    The presentation provides information taken from the arsenic demonstration program projects that have treatment systems removing multiply contaminants from drinking water. The case studies sited in the presentation consist of projects that have arsenic along with either nitrate, ...

  2. HYDROGEOLOGIC CASE STUDIES

    EPA Science Inventory

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  3. [Qualitative case study].

    PubMed

    Debout, Christophe

    2016-06-01

    The qualitative case study is a research method which enables a complex phenomenon to be explored through the identification of different factors interacting with each other. The case observed is a real situation. In the field of nursing science, it may be a clinical decision-making process. The study thereby enables the patient or health professional experience to be conceptualised. Copyright © 2016. Published by Elsevier Masson SAS.

  4. Studies in the History of Business Writing.

    ERIC Educational Resources Information Center

    Douglas, George H., Ed.; Hildebrandt, Herbert W., Ed.

    Because written communication has nearly always been the medium for transmitting information in the business world, these essays are a step toward providing a seminal statement on the history and practice of business writing. The essays in this volume are: "Business Writing and the Spread of Literacy in Late Medieval England" (Malcolm Richardson);…

  5. Studying the history of Indonesian astronomy: future prospects and possibilities

    NASA Astrophysics Data System (ADS)

    Orchiston, Wayne

    2017-08-01

    In this paper I identify a number of research topoics relating to Indonesian astronomical history that I feel are of international importance. Through these studies, Indonesia can make a valuable contribution to international history of astronomy. I also will discuss the role of SEAAN's new Working Group on Astronomical History and Heritage, and the values of the Journal of Astronomical History and Heritage and proceedings of the ICOA conferences as outlets for papers about Indonesian astronomical history. Finally, I mention chapters about Indonesia that will appear in a forthcoming book on the early development of astrophysics in Asia.

  6. Valeriu Bologa’s studies on the history of science

    PubMed Central

    BÂRSU, CRISTIAN

    2016-01-01

    History of science is a vast and complex domain, comprising many sub-domains, such as: the history of medicine, history of chemistry, history of physics etc. Different specialists in these sub-domains, trying to reach the general and integrative understanding of the history of science, succeeded only after they acquired a rich scientific experience in their fields of activity. One of the scientists who had interesting papers on the history of science was Valeriu Bologa (1892–1971). He was the first Romanian professor of history of medicine. Our paper presents some milestones regarding his preoccupations on the history of science. The aim of our study is to prove that, although he was primarily a historian of medicine, he surpassed this framework, proving to be a skillful historian of science. The topics of his works on the history of science included: the value of the unity of science, the ethical aspects of science during centuries, the interferences between the history of science and the history of medicine etc. PMID:27547069

  7. Valeriu Bologa's studies on the history of science.

    PubMed

    Bârsu, Cristian

    2016-01-01

    History of science is a vast and complex domain, comprising many sub-domains, such as: the history of medicine, history of chemistry, history of physics etc. Different specialists in these sub-domains, trying to reach the general and integrative understanding of the history of science, succeeded only after they acquired a rich scientific experience in their fields of activity. One of the scientists who had interesting papers on the history of science was Valeriu Bologa (1892-1971). He was the first Romanian professor of history of medicine. Our paper presents some milestones regarding his preoccupations on the history of science. The aim of our study is to prove that, although he was primarily a historian of medicine, he surpassed this framework, proving to be a skillful historian of science. The topics of his works on the history of science included: the value of the unity of science, the ethical aspects of science during centuries, the interferences between the history of science and the history of medicine etc.

  8. History and Utopian Ideology: The Case of the SS

    ERIC Educational Resources Information Center

    Arnold, Herbert A.

    1976-01-01

    In times of crisis, man seems to discover or rediscover utopias, identified with social discontent and the attempt to reconstruct history. Here is a brief look at an organization of the recent past whose vicious and notorious acts have tended to overshadow its attempt at constructing a theory, demonstrating all the characteristics of utopian…

  9. The Black Hills Case: On the Cusp of History.

    ERIC Educational Resources Information Center

    Pommersheim, Frank

    1988-01-01

    Discusses the legal history of ownership claim to Black Hills land in South Dakota by Lakota Sioux Indians and federal government. Examines progress of the Sioux Nation Black Hills Act (1987) as a way to establish a Sioux National Council, a vibrant legal panel linking the Lakota with their past. (TES)

  10. Longitudinal Analysis of Teacher Education: The Case of History Teachers

    ERIC Educational Resources Information Center

    Martell, Christopher Charles

    2011-01-01

    In the United States, learning history has traditionally been rooted in a transmission-oriented view of teaching and learning. From this perspective, teachers transfer their historical knowledge to their students. Alternatively, this dissertation positions itself within constructivist theories of teaching and learning, where learning is a process…

  11. Proficiency English Language Testing of International Employees: A Case History.

    ERIC Educational Resources Information Center

    Arena, Louis A.

    Developments in one major corporation's ongoing program to evaluate employees' English language proficiency are discussed. The testing program was developed by the multinational E. I. DuPont de Nemours corporation for use with international employees. The history and rationale for the selection of the five English tests used are outlined, the…

  12. Distance Learning Case Studies.

    ERIC Educational Resources Information Center

    Barker, Bruce O.

    The Office of Technology Assessment authorized a series of case studies in 1989 to investigate how technologies, services, and programs are implemented in distance education projects. The studies were also intended to look at the role of local, state, and federal agencies, and other public and private entities in providing educational services to…

  13. Artificial neural network modeling and cluster analysis for organic facies and burial history estimation using well log data: A case study of the South Pars Gas Field, Persian Gulf, Iran

    NASA Astrophysics Data System (ADS)

    Alizadeh, Bahram; Najjari, Saeid; Kadkhodaie-Ilkhchi, Ali

    2012-08-01

    Intelligent and statistical techniques were used to extract the hidden organic facies from well log responses in the Giant South Pars Gas Field, Persian Gulf, Iran. Kazhdomi Formation of Mid-Cretaceous and Kangan-Dalan Formations of Permo-Triassic Data were used for this purpose. Initially GR, SGR, CGR, THOR, POTA, NPHI and DT logs were applied to model the relationship between wireline logs and Total Organic Carbon (TOC) content using Artificial Neural Networks (ANN). The correlation coefficient (R2) between the measured and ANN predicted TOC equals to 89%. The performance of the model is measured by the Mean Squared Error function, which does not exceed 0.0073. Using Cluster Analysis technique and creating a binary hierarchical cluster tree the constructed TOC column of each formation was clustered into 5 organic facies according to their geochemical similarity. Later a second model with the accuracy of 84% was created by ANN to determine the specified clusters (facies) directly from well logs for quick cluster recognition in other wells of the studied field. Each created facies was correlated to its appropriate burial history curve. Hence each and every facies of a formation could be scrutinized separately and directly from its well logs, demonstrating the time and depth of oil or gas generation. Therefore potential production zone of Kazhdomi probable source rock and Kangan- Dalan reservoir formation could be identified while well logging operations (especially in LWD cases) were in progress. This could reduce uncertainty and save plenty of time and cost for oil industries and aid in the successful implementation of exploration and exploitation plans.

  14. Learning Historical Thinking with Oral History Interviews: A Cluster Randomized Controlled Intervention Study of Oral History Interviews in History Lessons

    ERIC Educational Resources Information Center

    Bertram, Christiane; Wagner, Wolfgang; Trautwein, Ulrich

    2017-01-01

    The present study examined the effectiveness of the oral history approach with respect to students' historical competence. A total of 35 ninth-grade classes (N = 900) in Germany were randomly assigned to one of four conditions--live, video, text, or a (nontreated) control group--in a pretest, posttest, and follow-up design. Comparing the three…

  15. History and Philosophy of Science through Models: The Case of Chemical Kinetics

    NASA Astrophysics Data System (ADS)

    Justi, Rosária; Gilbert, John K.

    The case for a greater role for the history and philosophy of science in science education is reviewed. It is argued that such a role can only be realised if it is based on both a credible analytical approach to the history and philosophy of science and if the evolution of a sufficient number of major themes in science is known in suitable detail. Adopting Lakatos' Theory of Scientific Research Programmes as the analytical approach, it is proposed that the development, use, and replacement, of specific models forms the core of such programmes.Chemical kinetics was selected as an exemplar major topic in chemistry. Eight models which have played a central role in the evolution of the study of chemical kinetics were identified by an analysis of the literature. The implications that these models have for the teaching and learning of chemistry today are discussed.

  16. Paradigm and ideology in psychiatric history writing: the case of psychoanalysis.

    PubMed

    Micale, M S

    1996-03-01

    The influence that paradigms may exert on scientific research programs is well established. The effect of organizing cognitive models on the writing of disciplinary histories, however, is less familiar although equally decisive. This essay explores the effects of ideological and paradigmatic factors on the construction of historical accounts of psychological medicine. Particular attention is paid to the scholarly case study of psychoanalysis, which for half a century determined the theories, themes, and figures discussed in psychiatric historiography, as well as the interpretations of these subjects. The author observes similar examples of the paradigmatic structuring of psychiatric history writing before and after the psychoanalytic era and speculates on whether it will ever be possible for psychiatry to achieve a single, stable, and consensual historical narrative about itself.

  17. Case study: a bridge across the paradigms.

    PubMed

    Luck, Lauretta; Jackson, Debra; Usher, Kim

    2006-06-01

    Case study as a teaching and research tool has an extensive history in health and social sciences. Despite its suitability for many of the research questions that face nurses, nurses have not fully embraced case study as a comprehensive approach for research. The vagaries of the real-life clinical setting can confound methodologically purist researchers. Case study provides a milieu in which nurse researchers can respond to these vagaries and move towards a paradigmatic openness. In this paper, we argue that case study offers, as yet, under-explored and under-utilised potential as a bridge across the traditional research paradigms. We argue that case study has broad research application and epistemological, ontological and methodological flexibility. When used as a research approach, case study is both the process and end product of research. It provides a delineated boundary for inquiry, and a structural process within which any methods appropriate to investigating a research area can be applied.

  18. Natural history and information overload: The case of Linnaeus

    PubMed Central

    Müller-Wille, Staffan; Charmantier, Isabelle

    2012-01-01

    Natural History can be seen as a discipline paradigmatically engaged in ‘data-driven research.’ Historians of early modern science have begun to emphasize its crucial role in the Scientific Revolution, and some observers of present day genomics see it as engaged in a return to natural history practices. A key concept that was developed to understand the dynamics of early modern natural history is that of ‘information overload.’ Taxonomic systems, rules of nomenclature, and technical terminologies were developed in botany and zoology to catch up with the ever increasing amount of information on hitherto unknown plant and animal species. In our contribution, we want to expand on this concept. After all, the same people who complain about information overload are usually the ones who contribute to it most significantly. In order to understand this complex relationship, we will turn to the annotation practices of the Swedish naturalist Carl Linnaeus (1707–1778). The very tools that Linnaeus developed to contain and reduce information overload, as we aim to demonstrate, facilitated a veritable information explosion that led to the emergence of a new research object in botany: the so-called ‘natural’ system. PMID:22326068

  19. Natural history and information overload: The case of Linnaeus.

    PubMed

    Müller-Wille, Staffan; Charmantier, Isabelle

    2012-03-01

    Natural History can be seen as a discipline paradigmatically engaged in 'data-driven research.' Historians of early modern science have begun to emphasize its crucial role in the Scientific Revolution, and some observers of present day genomics see it as engaged in a return to natural history practices. A key concept that was developed to understand the dynamics of early modern natural history is that of 'information overload.' Taxonomic systems, rules of nomenclature, and technical terminologies were developed in botany and zoology to catch up with the ever increasing amount of information on hitherto unknown plant and animal species. In our contribution, we want to expand on this concept. After all, the same people who complain about information overload are usually the ones who contribute to it most significantly. In order to understand this complex relationship, we will turn to the annotation practices of the Swedish naturalist Carl Linnaeus (1707-1778). The very tools that Linnaeus developed to contain and reduce information overload, as we aim to demonstrate, facilitated a veritable information explosion that led to the emergence of a new research object in botany: the so-called 'natural' system. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Mature vs. Active Deep-Seated Landslides: A Comparison Through Two Case Histories in the Alps

    NASA Astrophysics Data System (ADS)

    Delle Piane, Luca; Perello, Paolo; Baietto, Alessandro; Giorza, Alessandra; Musso, Alessia; Gabriele, Piercarlo; Baster, Ira

    2016-06-01

    Two case histories are presented, concerning the still poorly known alpine deep-seated gravitational slope deformations (DSD) located nearby Lanzada (central Italian Alps), and Sarre (north-western Italian Alps). The Lanzada DSD is a constantly monitored, juvenile, and active phenomenon, partly affecting an existing hydropower plant. Its well-developed landforms allow a precise field characterization of the instability-affected area. The Sarre DSD is a mature, strongly remodeled phenomenon, where the only hazard factor is represented by secondary instability processes at the base of the slope. In this case, the remodeling imposed the adoption of complementary analytical techniques to support the field work. The two presented studies had to be adapted to external factors, namely (a) available information, (b) geological and geomorphological setting, and (c) final scope of the work. The Lanzada case essentially relied upon accurate field work; the Sarre case was mostly based on digital image and DTM processing. In both cases a sound field structural analysis formed the necessary background to understand the mechanisms leading to instability. A back-analysis of the differences between the study methods adopted in the two cases is finally presented, leading to suggestions for further investigations and design.

  1. Geothermal Case Studies

    DOE Data Explorer

    Young, Katherine

    2014-09-30

    database.) In fiscal year 2015, NREL is working with universities to populate additional case studies on OpenEI. The goal is to provide a large enough dataset to start conducting analyses of exploration programs to identify correlations between successful exploration plans for areas with similar geologic occurrence models.

  2. Case Studies in Biology.

    ERIC Educational Resources Information Center

    Zeakes, Samuel J.

    1989-01-01

    A case study writing exercise used in a course on parasitology was found to be a powerful learning experience for students because it involved discipline-based technical writing and terminology, brought the students in as evaluators, applied current learning, caused interaction among all students, and simulated real professional activities. (MSE)

  3. Case Histories of Intense Pulsed Light Phototherapy in Dermatology - the HPPL™ and IFL(™) Technologies.

    PubMed

    Martella, Alessandro; Raichi, Mauro

    2017-03-13

    The intense pulsed light (IPL) and laser technologies are widely used for skin rejuvenation and for treating several dermatological disorders such as skin dyschromia and acne, and for non-ablative dermal remodeling of rhytides and hypertrophic scars. Technological evolution is rapid. The High Power Pulsed Light™ [HPPL™] and Incoherent Fast Light™ technologies [IFL™, Novavision Group S.p.A., 20826 Misinto (MB), Italy] are recent innovations in the field of IPL technologies; IFL™ is a further evolution of the already advanced HPPL™ system. The paper presents a selection of case histories of dermatological lesions treated with the HPPL™ and IFL™ technologies. All study materials were appropriately peer-reviewed for ethical problems.

  4. THE BIRTH OF LANGUAGE, THE CASE HISTORY OF A NON-VERBAL CHILD.

    ERIC Educational Resources Information Center

    KASTEIN, SHULAMITH; TRACE, BARBARA

    THE HISTORY OF A CHILD WITH BEHAVIOR AND LANGUAGE DISORDERS IS WRITTEN BY THE MOTHER IN CONJUNCTION WITH A SPEECH PATHOLOGIST. WRITTEN FROM A PROFESSIONAL VIEWPOINT, THE CASE HISTORY PRESENTS MEDICAL, EDUCATIONAL, PHYSICAL, AND SOCIAL DEVELOPMENTS AS THEY OCCURRED FROM BIRTH TO 11 YEARS OF AGE. TESTING PROCEDURES AND RESULTS, DIAGNOSIS, AND…

  5. THE BIRTH OF LANGUAGE, THE CASE HISTORY OF A NON-VERBAL CHILD.

    ERIC Educational Resources Information Center

    KASTEIN, SHULAMITH; TRACE, BARBARA

    THE HISTORY OF A CHILD WITH BEHAVIOR AND LANGUAGE DISORDERS IS WRITTEN BY THE MOTHER IN CONJUNCTION WITH A SPEECH PATHOLOGIST. WRITTEN FROM A PROFESSIONAL VIEWPOINT, THE CASE HISTORY PRESENTS MEDICAL, EDUCATIONAL, PHYSICAL, AND SOCIAL DEVELOPMENTS AS THEY OCCURRED FROM BIRTH TO 11 YEARS OF AGE. TESTING PROCEDURES AND RESULTS, DIAGNOSIS, AND…

  6. The Unheralded History of the Lemon Grove Desegregation Case

    ERIC Educational Resources Information Center

    Madrid, E. Michael

    2008-01-01

    In 1931, the Southern California community of Lemon Grove served as the unlikely stage for a dramatic and significant civil rights court case. A group of Mexican and Mexican-American parents and their children won a major victory in the battle against school segregation and the notion of separate but equal facilities. The case, now commonly…

  7. Hereditary xerocytosis. A case history and review of the literature.

    PubMed

    Nolan, G R

    1984-04-01

    A case of hereditary xerocytosis, a rare hemolytic anemia with dehydrated erythrocytes resulting from excess potassium efflux through the red cell membrane, is presented and the literature on the subject reviewed. This is one of the first cases reported from Australia.

  8. [The history of spondylolisthesis. The nineteenth century: early case reports, terminology, etiology and pathogenesis].

    PubMed

    Schlenzka, D

    2015-12-01

    The author describes the history of research and development of knowledge on lumbar spondylolisthesis. Based on the available literature, early case reports, creation of the terminology and etiological concepts are presented.

  9. A Course on Humanistic Creativity in Later Life: Literature Review, Case Histories, and Recommendations.

    ERIC Educational Resources Information Center

    Nuessel, Frank; Van Stewart, Arthur; Cedeno, Aristofanes

    2001-01-01

    Presents case histories of late-life creativity in literature (May Sarton), painting (Marcel Duchamp), music (Leos Janacek), dance (Martha Graham), and theatre (Jessica Tandy). Offers suggestions for a course on humanistic creativity in later life. (Contains 74 references.) (SK)

  10. A Course on Humanistic Creativity in Later Life: Literature Review, Case Histories, and Recommendations.

    ERIC Educational Resources Information Center

    Nuessel, Frank; Van Stewart, Arthur; Cedeno, Aristofanes

    2001-01-01

    Presents case histories of late-life creativity in literature (May Sarton), painting (Marcel Duchamp), music (Leos Janacek), dance (Martha Graham), and theatre (Jessica Tandy). Offers suggestions for a course on humanistic creativity in later life. (Contains 74 references.) (SK)

  11. Discovery and geology of the Desert Peak geothermal field: a case history. Bulletin 97

    SciTech Connect

    Benoit, W.R.; Hiner, J.E.; Forest, R.T.

    1982-09-01

    A case history of the exploration, development (through 1980), and geology of the Desert Peak geothermal field is presented. Sections on geochemistry, geophysics, and temperature-gradient drilling are included.

  12. Case history -- Reddell Oil Field -- Evangeline Parish, Louisiana

    SciTech Connect

    Austin, C.T.

    1996-12-31

    The purpose of this paper is to give the gravity meter credit as the main geophysical method used in the discovery of the Reddell Oil Field in Evangeline Parish, Louisiana. LL&E provided me with gravity data to use in the calculation of a salt model of the Reddell Salt Dome. The purpose of the study was to define the structure so the truncation of three (3) prospective sands in the Wilcox, Lower Eocene could be determined. The interpretation of the Reeddell Dome was complicated by the influence of the nearby Pine Prairie Salt Dome and both had to be modeled. A regional gravity was removed from the Bouguer gravity to give a Residual Gravity Map representing the gravity response to the salt domes. Gamma-gamma density logs were used to determine the density of the sediments and the contrasting densities between the sediments and the consistent salt density. Another input for the computer modeling program was a reference surface; in this case the top of the Louann salt, Lower Jurassic. The digital data are gridded with a square grid that is appropriate for the gravity control. The reference surface becomes a series of prisms whose height is a variable. The modeling program uses an iterative procedure to develop a salt structure whose computed gravity matches the input gravity. The domes were successfully modeled from the gravity and a discovery well was drilled at the Reddell Dome. This dome was later developed along with the Pine Prairie Dome.

  13. Case history -- Reddell Oil Field -- Evangeline Parish, Louisiana

    SciTech Connect

    Austin, C.T. )

    1996-01-01

    The purpose of this paper is to give the gravity meter credit as the main geophysical method used in the discovery of the Reddell Oil Field in Evangeline Parish, Louisiana. LL E provided me with gravity data to use in the calculation of a salt model of the Reddell Salt Dome. The purpose of the study was to define the structure so the truncation of three (3) prospective sands in the Wilcox, Lower Eocene could be determined. The interpretation of the Reeddell Dome was complicated by the influence of the nearby Pine Prairie Salt Dome and both had to be modeled. A regional gravity was removed from the Bouguer gravity to give a Residual Gravity Map representing the gravity response to the salt domes. Gamma-gamma density logs were used to determine the density of the sediments and the contrasting densities between the sediments and the consistent salt density. Another input for the computer modeling program was a reference surface; in this case the top of the Louann salt, Lower Jurassic. The digital data are gridded with a square grid that is appropriate for the gravity control. The reference surface becomes a series of prisms whose height is a variable. The modeling program uses an iterative procedure to develop a salt structure whose computed gravity matches the input gravity. The domes were successfully modeled from the gravity and a discovery well was drilled at the Reddell Dome. This dome was later developed along with the Pine Prairie Dome.

  14. Papers of the Society for the Study of Curriculum History.

    ERIC Educational Resources Information Center

    Tanner, Laurel N., Ed.

    The 13 papers that comprise this collection were, with certain exceptions, presented at the first and second annual meetings of the Society for the Study of Curriculum History. Papers by the society's members, who attempt to achieve more disciplined inquiry into the history of curriculum, include: (1) "What We Can Learn from Our Experiences…

  15. A Gateway to Social Studies through Topical History

    ERIC Educational Resources Information Center

    van Scotter, Richard; White, William E.; Hartoonian, H. Michael; Davis, James E.

    2007-01-01

    The Colonial Williamsburg Foundation, the nation's largest living history museum, in partnership with the Social Science Education Consortium, scholars, educators, and teachers, has developed engaging learning materials for social studies classrooms. One such program is the Colonial Williamsburg History and Civics Project, which is based on…

  16. The Scientific Study of Adolescence: A Brief History

    ERIC Educational Resources Information Center

    Steinberg, Laurence; Lerner, Richard M.

    2004-01-01

    This article provides an overview of the history of research on adolescence. In our view, the history of the scientific study of adolescence has had two overlapping phases and is now on the cusp of a third. The first phase, which began early in the 20th century and lasted about 70 years, was characterized by grand theoretical models that…

  17. National Pride and Students' Attitudes towards History: An Exploratory Study

    ERIC Educational Resources Information Center

    Andrews, Rhys; McGlynn, Catherine; Mycock, Andrew

    2010-01-01

    Recent debates about "Britishness" have drawn increasing attention to the inculcation of national values within the school history curriculum. To date, however, few studies have explored young people's attitudes towards history or how these are related to their sources of national pride and shame. This paper draws on a survey of over 400…

  18. A Gateway to Social Studies through Topical History

    ERIC Educational Resources Information Center

    van Scotter, Richard; White, William E.; Hartoonian, H. Michael; Davis, James E.

    2007-01-01

    The Colonial Williamsburg Foundation, the nation's largest living history museum, in partnership with the Social Science Education Consortium, scholars, educators, and teachers, has developed engaging learning materials for social studies classrooms. One such program is the Colonial Williamsburg History and Civics Project, which is based on…

  19. The History of Education and the Study of Educational Administration

    ERIC Educational Resources Information Center

    Sungaila, Helen

    2008-01-01

    The nexus between the fields of the administration and history of education is obvious. Can the contribution of the study of the history of education "to the development of educational administration as a discipline"--that is, as "an area of academic and theoretical research"--safely be taken for granted? Such a question, of course, is of little…

  20. Repackaging the Past: Commodification, Consumerism and the Study of History

    ERIC Educational Resources Information Center

    Armstrong, Paul; Coles, Janet

    2008-01-01

    In this paper, we argue against the over-simplistic accusation that the media "dumb down" the study of history. Instead, we critically examine the contemporary presentation of history on British television within a framework of analysis of commodification and consumption. We argue that central to the debate is the idea that whilst…

  1. Sour-gas sweetening during offshore drillsteam tests; A case history

    SciTech Connect

    Casselman, R.L. )

    1990-03-01

    This case history details the use of a sour-gas sweetener on two exploratory well drillstem tests (DST's) offshore California. Also included is a brief description of the process and comments on future plans. This case history is intended to show that the process can be applied effectively in a sour-gas offshore DST. It shows performance on each of the exploratory wells and explains the solutions initiated to mitigate problems incurred in subsequent DST's.

  2. Management of dental implant fractures. A case history.

    PubMed

    Al Quran, Firas A M; Rashan, Bashar A; Al-Dwairi, Ziad N

    2009-01-01

    The widespread use of endosseous osseointegrated implants to replace missing natural teeth increases the chances of implant complications and failures, despite the high initial success rate reported in the literature. Implant fracture is one possible complication that results in ultimate failure of the dental implant. Such a complication poses a management crisis even for the most experienced clinician. This article reports on a case of implant fracture, its possible causes, and how the case was managed.

  3. Water Detection Response Team Geophysics Element Case Histories

    DTIC Science & Technology

    1990-09-01

    34 on the surface by conducting one or more types of geophysical tests at that point. In the ideal case, the aquifer thickness and water quality would...The Geophysics Element has been deployed to participate in several major military exercises. Case historics of the Geophysics Element involvement in...ber who will advise the well drillers and reinterpret the geophysical survey results on the basis of drilling results, if necessary. This operating

  4. Binary 4D seismic history matching, a metric study

    NASA Astrophysics Data System (ADS)

    Chassagne, Romain; Obidegwu, Dennis; Dambrine, Julien; MacBeth, Colin

    2016-11-01

    This paper explores 4D seismic history matching and it specifically focuses on the objective function used during the optimisation with seismic data. The objective function is calculated by using binary maps, where one map is obtained from the observed seismic data and the other is from one realisation of the optimisation algorithm from the simulation model. In order to decide which set of parameters is a relevant update for the simulation model, an efficient way is required to measure how similar these two binary images are, during their evaluation within the objective function. Behind this aspect of quantification of the similarities or dissimilarities lies the metric notion, or the art of measuring distances. Four metrics are proposed with this study, the well-known Hamming distance, two widely used metrics, the Hausdorff distance and Mutual Information and a recent metric, called the Current Measure Metric. These metrics will be tested and compared on different case scenarios, designed in accordance to a real field case (gas exsolution) before being used in the second part of the paper. Despite its simplicity, the Hamming distance gives positive results, but the Current Measure Metric appears to be a more efficient choice to cover a wider range of scenarios, these conclusions remain true when tested on synthetic and real dataset in a history matching exercise. Some practical aspects of binary map processes will be examined through the paper, as it is shown that it is more proper to use a derivative free optimisation algorithm and a proper metric should be more inclined to capture global features than local features.

  5. Case History Risk Factors for Specific Language Impairment: A Systematic Review and Meta-Analysis.

    PubMed

    Rudolph, Johanna M

    2017-08-15

    Research suggests that the best approach to early identification of children with specific language impairment (SLI) should include assessment of risk factors. However, previous attempts to develop a list for this purpose have been unsuccessful. In this study, systematic review and meta-analytic procedures were used to determine whether any case history factors can be used to identify toddlers at risk of developing SLI. Epidemiological studies that examined the association between risk factors and SLI were identified. Results across studies were aggregated to determine more precisely the strength of association between each risk factor and the development of SLI. The clinical significance of these factors was established via comparison to late talker status. Eleven risk factors were found to be statistically significant predictors of SLI. Among these, maternal education level, 5-min Apgar score, birth order, and biological sex met criteria for clinical significance. At least 4 case history factors are as predictive as late talker status in the context of early identification of toddlers at risk for SLI. The findings of this review highlight the importance of taking a child's genetic and environmental context into consideration when deciding whether further evaluation and early intervention services are warranted. https://doi.org/10.23641/asha.5150122.

  6. Jargon: A barrier in case history taking? - A cross-sectional survey among dental students and staff.

    PubMed

    Subramaniam, R; Sanjeev, R; Kuruvilla, Suneesh; Joy, Mathew T; Muralikrishnan, B; Paul, John

    2017-01-01

    The use of jargon has become very common in the healthcare field, especially in medical/dental records. Although the use of standard medical jargon can be seen as professional, efficient shorthand, a lack of awareness regarding the standard medical abbreviations and incessant and overzealous use of slang among the healthcare professionals can act as a barrier to effective communication and understanding among patients and peers. The aim of this study was to assess the acceptance and use of jargon in case history taking among clinical dental students and dental teaching faculty members of dental colleges in Ernakulam and Idukki districts of Kerala. A cross-sectional questionnaire-based survey was carried out, consisting of 15 questions, to assess the objectives of the study. The study was conducted among clinical dental undergraduate students, house surgeons, postgraduate students and teaching faculty members of five dental colleges in Ernakulam and Idukki districts, Kerala. The results were expressed as a number and percentage of response for each question and Chi-squared test was used for inferential statistical analysis. All the 549 respondents used jargon in case history taking. Approximately 22.4% of the respondents admitted that they always used jargon and 55.8% admitted of using jargon only when there was a lack of time. The majority of the respondents (71.4%) learned the jargon from their colleagues. Approximately 50% of the respondents admitted use of jargon in a history section and about 32% of the respondents in all the sections of case history taking. Approximately 74% were of the opinion that abbreviations should be permitted in case history taking. This study showed widespread use of jargon/abbreviations in case history taking among the respondents. There is a lack of knowledge regarding standard medical abbreviations. Although the majority of the respondents were comfortable with the use of jargon, the majority of the postgraduates and faculty members

  7. Teaching History with Museums: Strategies for K-12 Social Studies

    ERIC Educational Resources Information Center

    Marcus, Alan; Stoddard, Jeremy; Woodward, Walter W.

    2011-01-01

    "Teaching History with Museums" provides an introduction and overview of the rich pedagogical power of museums. In this comprehensive textbook, the authors show how museums offer a sophisticated understanding of the past and develop habits of mind in ways that are not easily duplicated in the classroom. Using engaging cases to illustrate…

  8. Teaching History with Museums: Strategies for K-12 Social Studies

    ERIC Educational Resources Information Center

    Marcus, Alan; Stoddard, Jeremy; Woodward, Walter W.

    2011-01-01

    "Teaching History with Museums" provides an introduction and overview of the rich pedagogical power of museums. In this comprehensive textbook, the authors show how museums offer a sophisticated understanding of the past and develop habits of mind in ways that are not easily duplicated in the classroom. Using engaging cases to illustrate…

  9. Qualitative Case Study Guidelines

    DTIC Science & Technology

    2013-11-01

    methods in public relations and marketing communications. New York, Routledge 166-185 13. Denzin , N. K. (1978) The Research Act: A Theoretical...Introduction to Sociological Methods. 2nd ed. New York, McGraw-Hill 14. Denzin , N. K. and Lincoln, Y. S. (2011) The SAGE Handbook of Qualitative...The Art of Science. In: Denzin , N. K. and Lincoln, Y. S. (eds.) Handbook of Qualitative Research. Thousand Oaks, Sage 19. GAO (1990) Case Study

  10. Remediation case studies: Bioremediation

    SciTech Connect

    1995-03-01

    The purpose of this report is to provide case studies of site cleanup projects utilizing bioremediation. This volume contains reports on nine projects that include bioventing and land treatment technologies, as well as a unique, large-scale slurry-phase project. In these projects, petroleum hydrocarbons are the most frequent contaminants of concern. Two land treatment projects in this volume represent completed cleanups at creosote sites.

  11. Lightning - Apollo to Shuttle. [case histories and spacecraft protection

    NASA Technical Reports Server (NTRS)

    Durrett, W. R.

    1976-01-01

    The history of lightning striking NASA spacecraft and the development of lightning protection systems is reviewed from the Apollo 12 flight, involving a lightning strike thirty six seconds after launch, to the present date. Particular attention is paid to problems that may arise in this field in the context of planning and implementing the Space Shuttle program. The lightning protection design for Apollo is described: a folding mast mounted on top of the hammerhead crane on top of the Launcher Umbilical Tower, with a lightning rod on top. The effect of lightning storms on the launches of Apollos 12 through 17 is examined, as is the effect of lightning in the Skylab program. The lightning problems encountered by the Apollo-Soyuz mission and by the two unmanned Viking launches to Mars are discussed. The Lightning Detection And Ranging system for detecting RF emission from lightning discharges is described.

  12. Short diet history for assessing dietary exposure to N-nitrosamines in epidemiologic studies

    SciTech Connect

    Howe, G.R.; Harrison, L.; Jain, M.

    1986-10-01

    A short diet history for use in assessing dietary nitrosamine exposure in epidemiologic studies has been developed by using data form a case-control study of diet and stomach cancer carried out in Ontario, Manitoba, and Newfoundland between 1979 and 1982. The method gives excellent correlations for seven dietary components with estimates based on a full diet history, and also performs well when tested on a different data set from a case-control study of diet and colorectal cancer carried out in Ontario and Alberta between 1976 and 1978.

  13. Sudden unexplained death in childhood: A comparison of cases with and without a febrile seizure history.

    PubMed

    Hesdorffer, Dale C; Crandall, Laura A; Friedman, Daniel; Devinsky, Orrin

    2015-08-01

    We considered whether a subset of children with sudden unexplained death in childhood (SUDC) and a history of febrile seizures (FS) may parallel those in sudden unexpected death in epilepsy (SUDEP). The prevalence of a history of FS was examined, and factors that may distinguish SUDC cases with and without FS were described. Characteristics were assessed in 123 consecutive children with SUDC reported to the SUDC program (4/1/11-3/31/14) by their parents. Parental interview covered the decedent's medical history, circumstances of death, environmental factors, cause of death, and family medical history. Features of SUDC cases were compared by FS history. Overall, 31.7% of SUDC cases had a history of FS, among which 74.4% had simple FS. Compared to those without a history of FS, a history of FS was associated with a greater median age at death (p = 0.03) and death during the weekdays (p = 0.02). Terminal fever was similar in those with and without FS. The median time from FS to death was 6.0 months (interquartile range [IQR] 3.0-10.0). In all SUDC cases, prone position at death, death during sleep, and unwitnessed deaths predominated. There are parallels among SUDC, sudden infant deaths, and sudden unexpected death in epilepsy (SUDEP) with regard to prone position, unwitnessed deaths mostly during sleep, and male predominance. In children with SUDC and a history of FS, terminal fever may increase the risk for an unwitnessed terminal seizure. The greater than expected prevalence of a FS history and the proportion with terminal fever or illness in this cohort suggests that some SUDC deaths may be seizure related and therefore have potential commonalities with SUDEP. Wiley Periodicals, Inc. © 2015 International League Against Epilepsy.

  14. Evaluation of forensic medical history taking from the child in cases of child physical and sexual abuse and neglect.

    PubMed

    Drummond, Rachel; Gall, John A M

    2017-02-01

    Suspected child physical abuse, sexual abuse and neglect are not uncommon presentations. As part of the assessment of these cases, a forensic medical history may be taken. This forensic history is used not only to determine the steps necessary to address the child's wellbeing but also to direct the forensic examination. Currently, there is no clear consensus on whether or not a forensic medical history should consistently be considered an integral element within the paediatric forensic evaluation. This study examines the value derived by the medical practitioner taking a forensic medical history rather than relying on hearsay evidence when a child presents for an assessment. A retrospective review of paediatric cases seen by the Victorian Forensic Paediatric Medical Service (VFPMS) between 2014 and 2015 was undertaken. 274 forensic case reports were reviewed and the data was entered into an Excel spread sheet and analysed using chi squared tests within STATA(®). With increasing age of the child, a forensic medical history is significantly more likely to be taken. Additional information is made available to the medical practitioner what would otherwise have been provided if the medical practitioner relied only on the interview conducted by the police. Discrepancies observed between the official third parties (police or child protection) report of what a child has said and what the child says to the medical practitioner decrease with age, as do discrepancies observed between the child's version of events and a third party's (eg. parents, caregivers, friends) version of events. The study showed that by taking a forensic medical history from the child additional information can be obtained. Further, that there is a value in the examining medical practitioner taking a forensic medical history from children in cases of child physical and sexual abuse and neglect. Copyright © 2017 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  15. The Rainbow and the Achromatic Telescope: Two Case Studies.

    ERIC Educational Resources Information Center

    Rudd, M. Eugene

    1988-01-01

    Presented are two case studies on the perspective of the history of science. Provided are the contributions of 12 famous scientists with their historical illustrations and diagrams. Five conclusions are drawn from these studies. (YP)

  16. The Rainbow and the Achromatic Telescope: Two Case Studies.

    ERIC Educational Resources Information Center

    Rudd, M. Eugene

    1988-01-01

    Presented are two case studies on the perspective of the history of science. Provided are the contributions of 12 famous scientists with their historical illustrations and diagrams. Five conclusions are drawn from these studies. (YP)

  17. Exploration case studies

    NASA Astrophysics Data System (ADS)

    Underwood, Jimmy M.

    1989-04-01

    NASA's Office of Exploration has undertaken four case studies for prospective expansion of manned space activities beyond earth orbit. The subjects of these studies are (1) an expedition to the Martian moon Phobos; (2) a three-mission expedition to Mars; (3) the construction of a man-tended lunar observatory; and (4) the construction of a lunar outpost to serve as the basis for construction of a Martian outpost. The fourth alternative would follow the recommendation of the National Commission on Space for the creation of a 'bridge between worlds' in which explorers would develop ways in which to 'live off the land' in a space environment.

  18. Mr. Stinson's Vietnam: Moral Ambiguity in the History Classroom. Teaching Cases in Cross-Cultural Education, No. 11.

    ERIC Educational Resources Information Center

    Wineburg, Samuel S.; Kleinfeld, Judith, Ed.

    This document proposes a case study approach to U.S. history instruction. The method which the document suggests arises from an actual class discussion of the My Lai massacre that occurred during the Vietnam War. A sample class discussion concerns the setting of standards to guide national and international affairs and the particular standards…

  19. [Cholera in a Paris resident with no history of travel. A case report].

    PubMed

    Infuso, A; de Valk, H; Bigot Marie, C; Fournier, J M; Cadiot, G; Andremont, A; Desenclos, J C

    1998-02-07

    Cases of imported cholera are frequently observed, but cholera almost never occurs in subjects who have never travelled to an endemic area. In the last 30 years, 4 cases have been reported. We report an indigenous case diagnosed in Paris in September 1996. The patient was hospitalized for severe dehydration and acute renal failure. Cultures of a fecal specimen grew Vibrio cholerae O1 Ogawa serotype. An epidemiological study was conducted to identify the vehicle and mode of contamination and suggested that this case was associated with the consumption of fresh sorrel imported from West Africa. No other cases were identified in contacts of the patient. Asymptomatic carriage of V. cholerae is rare. However, air travel has allowed people to arrive in non-endemic areas during the incubation period. The agent may also be transported in contaminated foods. Cholera should be suspected in all adults presenting acute watery diarrhea with severe dehydration. History taking should also look for risk exposure and these patients should be systematically asked about possible exposures.

  20. Social Studies Secondary Curriculum Guide on Russian History. World History Series. Bulletin No. 258.

    ERIC Educational Resources Information Center

    Montgomery County Public Schools, Rockville, MD.

    This guide outlines a nine to eighteen week course of study for secondary level students on the history of Russia and the Soviet Union. The course teaches the concepts of change and continuity, cause and effect, structural complexity, societal interdependence, freedom and obligation, human needs and cultural functioning, and national behavior…

  1. Social Studies Secondary Curriculum Guide on Far Eastern History. World History Series, Bulletin No. 256.

    ERIC Educational Resources Information Center

    Perialas, Stephen

    This secondary level curriculum guide provides a program and identifies materials for the study of the history and culture of China and Japan. The purpose of the course is to provide exercises that require students to research, question, analyze, synthesize, and evaluate historical data. Each lesson contains behavior and content objectives,…

  2. The history of scatter hoarding studies

    PubMed Central

    Brodin, Anders

    2010-01-01

    In this review, I will present an overview of the development of the field of scatter hoarding studies. Scatter hoarding is a conspicuous behaviour and it has been observed by humans for a long time. Apart from an exceptional experimental study already published in 1720, it started with observational field studies of scatter hoarding birds in the 1940s. Driven by a general interest in birds, several ornithologists made large-scale studies of hoarding behaviour in species such as nutcrackers and boreal titmice. Scatter hoarding birds seem to remember caching locations accurately, and it was shown in the 1960s that successful retrieval is dependent on a specific part of the brain, the hippocampus. The study of scatter hoarding, spatial memory and the hippocampus has since then developed into a study system for evolutionary studies of spatial memory. In 1978, a game theoretical paper started the era of modern studies by establishing that a recovery advantage is necessary for individual hoarders for the evolution of a hoarding strategy. The same year, a combined theoretical and empirical study on scatter hoarding squirrels investigated how caches should be spaced out in order to minimize cache loss, a phenomenon sometimes called optimal cache density theory. Since then, the scatter hoarding paradigm has branched into a number of different fields: (i) theoretical and empirical studies of the evolution of hoarding, (ii) field studies with modern sampling methods, (iii) studies of the precise nature of the caching memory, (iv) a variety of studies of caching memory and its relationship to the hippocampus. Scatter hoarding has also been the subject of studies of (v) coevolution between scatter hoarding animals and the plants that are dispersed by these. PMID:20156813

  3. Using History To Teach Scientific Method: The Case of Argon

    NASA Astrophysics Data System (ADS)

    Giunta, Carmen J.

    1998-10-01

    The history of science is full of stories that exhibit scientific methodology to an exemplary degree. Such stories can be vehicles for the teaching of scientific thought to non-science majors in general-education science courses, particularly if they do not involve much technical background and are told in ordinary language. This paper illustrates the kind of lessons that can be gleaned from such stories by examining the discovery of argon, an episode replete with examples of how scientists pursue knowledge. Lord Rayleigh's use of multiple methods to determine the density of nitrogen; his persistent tracking down of a small but real anomaly in those measurements; his and William Ramsay's eventual realization that the anomaly was due to a previously unknown but relatively plentiful component of the atmosphere, an inert, monatomic gas; and Ramsay's subsequent successful search for other members of the inert gas family all illustrate the scientific approach to knowledge. This story can be presented to students in Rayleigh's words, annotated to supply background material and to pose questions.

  4. Glioblastoma multiforme in patients with history of extracranial cancer: Case series.

    PubMed

    Kalita, O; Trojanec, R; Megova, M; Hajduch, M; Vaverka, M; Hrabalek, L; Zlevorova, M; Drabek, J; Tuckova, L; Vrbkova, J

    2016-05-01

    Significant progress in treatment strategies improves the expectations of patients with extracranial cancers. Metastases are the primary consideration in patients with cancer history. In the case of neurologic disorders, the patient should undergo brain MRI. A rationale is presented for surgery, whole-brain or stereotactic radiotherapy, or chemotherapy. Recently, we have encountered misdiagnosed primary malignant brain tumours in patients with oncologic history who had been admitted for surgery for brain metastases. The aim of our study is to evaluate the incidence of concurrent cancers, to assess the relationship between previous cancer staging and primary brain tumour evaluation as well as to determine treatment efficiency. From January 2007 to December 2011, we prospectively followed up patients with concurrent history of both extracranial cancer and subsequent glioblastoma multiforme. Information was collected on the clinical condition, imaging, history of extracranial cancer, previous and present surgical and oncologic procedures, and GBM histologic, cytogenetic, and molecular genetic investigations. Five patients were recruited: three females and two males. The average patient age at the time of GBM diagnosis was 65.6 years. Three patients had a history of breast carcinoma, one of renal carcinoma and one of colorectal carcinoma. Following the diagnosis of carcinoma, three patients received chemotherapy and radiotherapy, one patient had radiotherapy alone, and one had no adjuvant therapy. In all the cases, surgery revealed primary GBM, with a standard occurrence of genetic abnormalities (Table 1). The average time from the diagnosis of extracranial cancer to that of GBM was 4 years. Four patients underwent chemoradiotherapy and one had palliative radiotherapy. Two patients completed oncotherapy and their OS was 27 months and 19 months, respectively. One patient had post-surgical progression of hemiparesis. One patient had pulmonary embolism during oncotherapy

  5. Reasoning with case histories of process knowledge for efficient process development

    NASA Technical Reports Server (NTRS)

    Bharwani, Seraj S.; Walls, Joe T.; Jackson, Michael E.

    1988-01-01

    The significance of compiling case histories of empirical process knowledge and the role of such histories in improving the efficiency of manufacturing process development is discussed in this paper. Methods of representing important investigations as cases and using the information from such cases to eliminate redundancy of empirical investigations in analogous process development situations are also discussed. A system is proposed that uses such methods to capture the problem-solving framework of the application domain. A conceptual design of the system is presented and discussed.

  6. Reasoning with case histories of process knowledge for efficient process development

    NASA Technical Reports Server (NTRS)

    Bharwani, Seraj S.; Walls, Joe T.; Jackson, Michael E.

    1988-01-01

    The significance of compiling case histories of empirical process knowledge and the role of such histories in improving the efficiency of manufacturing process development is discussed in this paper. Methods of representing important investigations as cases and using the information from such cases to eliminate redundancy of empirical investigations in analogous process development situations are also discussed. A system is proposed that uses such methods to capture the problem-solving framework of the application domain. A conceptual design of the system is presented and discussed.

  7. History and Applications of Dust Devil Studies

    NASA Astrophysics Data System (ADS)

    Lorenz, Ralph D.; Balme, Matthew R.; Gu, Zhaolin; Kahanpää, Henrik; Klose, Martina; Kurgansky, Michael V.; Patel, Manish R.; Reiss, Dennis; Rossi, Angelo Pio; Spiga, Aymeric; Takemi, Tetsuya; Wei, Wei

    2016-11-01

    Studies of dust devils, and their impact on society, are reviewed. Dust devils have been noted since antiquity, and have been documented in many countries, as well as on the planet Mars. As time-variable vortex entities, they have become a cultural motif. Three major stimuli of dust devil research are identified, nuclear testing, terrestrial climate studies, and perhaps most significantly, Mars research. Dust devils present an occasional safety hazard to light structures and have caused several deaths.

  8. Studies in the history of astronomy. Number 19, 1987

    NASA Astrophysics Data System (ADS)

    Gurshtein, A. A.

    Papers are presented on such topics as the history of the exploration of Venus, the history of the discovery of the relic radiation, Copernicus' star catalog, Euler's contribution to potential theory in connection with the theory of the earth's figure, the role of astrology in ancient culture, and the history of the study of astronomical refraction. Attention is also given to astronomy in Kazakhstan during the Second World War, the contribution of Arago to the development of astrophysics instrumentation, and the work on astronomy written by Kirik of Novgorod in the year 1136.

  9. Case Histories of Four Extremely Intense Rockbursts in Deep Tunnels

    NASA Astrophysics Data System (ADS)

    Zhang, Chuanqing; Feng, Xia-Ting; Zhou, Hui; Qiu, Shili; Wu, Wenping

    2012-05-01

    In the process of excavating seven parallel tunnels at the Jinping II Hydropower Station, several extremely intense rockbursts occurred, killing and injuring construction workers and damaging several sets of equipment. Based on the characteristics and mechanisms of these rockbursts, four typical events were selected and their temporal and spatial characteristics were here described in detail. The geological conditions revealed after the rockbursts were surveyed carefully. The responses of support elements were also analyzed. The details documented in each case provide not only an important reference for understanding the development mechanisms of rockbursts but also a basis for the selection and development of rockburst prevention measures in deep hard rock tunnels.

  10. Isolated cases? The history and historiography of Australian medical research.

    PubMed

    Hobbins, Peter; Hillier, Kathryn

    2010-01-01

    For over two hundred years, Australia has been portrayed as a terminus rather than a hub for scientific exchange. Alongside narratives valorising the struggle for a distinct national identity, the motif of isolation abounds in the historiography of Australian medical research. Yet these orthodoxies are ripe for rescripting, as illustrated by a symposium held in Sydney in 2010: Isolated Cases? 100 Years of Australian Medical Research. Weaving together several historical themes from this conference with wider historiographic threads, this article questions many prevailing representations. In particular the authors argue that rather than isolation or dependency, Australian medical science has been characterised by a profound interdependence across two centuries of antipodean endeavour.

  11. Building a Constructivist Practice: A Longitudinal Study of Beginning History Teachers

    ERIC Educational Resources Information Center

    Martell, Christopher C.

    2014-01-01

    This longitudinal interpretative case study examined the constructivist beliefs and related practices of four secondary history teachers from their teacher preparation through their first year in the classroom. The results of this study showed that issues of classroom control were major barriers for the implementation of constructivist-oriented…

  12. The history of pharmacy studies in Croatia.

    PubMed

    Kujundzić, N; Inić, S

    2014-02-01

    The first study of pharmacy on Croatian territory was founded in the early 19th century (1806-1813). Vicencio Dandolo (1758-1819), a pharmacist from Venice who was Napoleon's governor of Dalmatia, established a lyceum in Zadar in 1806. It included education for pharmacists. The Lyceum (later the Central School) was closed in 1811. The founding of the modern University of Zagreb (1874) and its Department of Mathematics and Natural Sciences (1876) created the conditions for the development of university education for pharmacists. The study of pharmacy was introduced at the University of Zagreb in 1882 through the efforts of the Croatian-Slavonian Pharmaceutical Association and the professors of the Faculty of Philosophy. The study went through a series of reforms. The most significant one came with the introduction of the four-year study of pharmacy and the establishment of the Pharmacy Department of the Faculty of Philosophy (1928). The independent Faculty of Pharmacy (today's Faculty of Pharmacy and Biochemistry) was founded at the University of Zagreb in 1942. Since 1989, it has had two separate studies (Pharmacy and Medical Biochemistry).

  13. Partial trisomy 19p: case report and natural history.

    PubMed

    Salbert, B A; Solomon, M; Spence, J E; Jackson-Cook, C; Brown, J; Bodurtha, J

    1992-03-01

    Partial trisomy 19p was noted in an infant delivered at 39 weeks gestation with intrauterine growth retardation (IUGR), bilateral club feet, renal abnormalities, hearing deficit, and multiple dysmorphic features. Chromosomes obtained following amniocentesis at 32 weeks gestation revealed that the fetus was partially trisomic for 19p and partially monosomic for a portion of the terminal band of 3q, having inherited a derivative chromosome 3 from her father [46,XX,-3,+der(3)t(3;19)(q29;p13.2)pat]. The father was found to be the carrier of a balanced translocation between chromosomes 3 and 19 [46,XY,t(3;19)(q29;p13.2)]. The only other case of partial trisomy 19p previously reported was an infant with partial trisomy 19p and partial monosomy 13q who died at 59 days of age. This report by Byrne et al. [(Am J Hum Genet 1980: 32:64A] is similar to our case with respect to IUGR, small palpebral fissures, and ear anomalies.

  14. History of migration studies in biological anthropology.

    PubMed

    Mascie-Taylor, C G Nicholas; Little, Michael A

    2004-01-01

    The earliest studies of human biological factors in migration in which a clear research design was employed date back to the early 20th century in the United States. Maurice Fishberg's study of Jewish migrants, published in 1905, antedated the classic study of Franz Boas initiated in 1908. There have been two main approaches. The first approach examined the impact of migration in relation to changing environment and the importance of environmental plasticity. For example, Fishberg reported that migrants had offspring different in stature from themselves and with differences thought to be due to improvements in the environment, although some selection of genetically determined traits was suggested. Subsequently, a number of research designs have been used, ranging from Boas's simple design of sedente (nonmigrant) adults and children compared with first- and second-generation migrants; Shapiro's extension of this study in Japanese migrants to Hawai'i; Goldstein's four-fold comparison of Mexican sedentes and their offspring in Mexico, and migrants to the USA and their offspring in the USA; and Lasker's extension of Goldstein's Mexican study by including comparison of sedentes with returning emigrants. More sophisticated designs were used by Harrison and Baker in examining altitude effects and changes in subsistence and lifestyle during the 1960s through to the 1980s. The second approach has focused on the effect of migration on gene flow. For example, the clinal variation of ABO blood groups in Europe and Australia is generally purported to result from past migration, although increasing random migration for blood groups is likely to eliminate clinal variation. Migration has usually been considered from a spatial (geographic) perspective, but more recent studies have also investigated the impact of social or occupational movement (social mobility) alone, or in combination with geographic migration, and tested whether such movements are selective or random for a number

  15. Social Studies: Great Debates in American History.

    ERIC Educational Resources Information Center

    Kleiman, Marsha

    This elective course in American Studies, one of a series revised to fit the quinmester organization of schools, is intended for 10th through 12th grade students. The aim of the course is for students to develop their capacity to examine and make judgements about controversial issues of the past and present. Emphasis is on an analysis of selected…

  16. A Family History Study of Asperger Syndrome

    ERIC Educational Resources Information Center

    Ghaziuddin, Mohammad

    2005-01-01

    Asperger syndrome (AS) is a childhood-onset disorder often described as a mild variant of autism. Although classified as a distinct disorder in the DSM-IV, its overlap with autism continues to be a matter of ongoing debate. While the family genetic origins of autism are well established, few studies have investigated this topic in AS using current…

  17. The History of the Study of Detonation

    ERIC Educational Resources Information Center

    Bulat, Pavel V.; Volkov, Konstantin N.

    2016-01-01

    In this article we reviewed the main concepts of detonative combustion. Concepts of slow and fast combustion, of detonation adiabat are introduced. Landmark works on experimental and semi-empirical detonation study are presented. We reviewed Chapman-Jouguet stationary detonation and spin detonation. Various mathematical model of detonation wave…

  18. Conducting and Reporting Case Studies.

    ERIC Educational Resources Information Center

    Lichtman, Merilyn; Taylor, Satomi Izumi

    Issues and elements of case study research are explored and illustrated with the example of a case study of a kindergarten in a suburb of Tokyo (Japan). Case study research is a type of qualitative research that concentrates on a single unit or entity, with boundaries established by the researcher. The case is an example drawn from a larger class,…

  19. Autoimmune lymphoproliferative syndrome (ALPS). Case report and family history.

    PubMed

    Ries, F; Ferster, A; Rieux-Laucat, F; Biwer, A; Dicato, M

    2010-01-01

    Autoimmune lymphoproliferative syndrome (ALPS) is a rare disease caused by defective lymphocyte apoptosis and is characterized by non-malignant lymphoproliferation, hepatosplenomegaly, autoimmune manifestations and increased risk of both Hodgkin's and non-Hodgkin's lymphoma. Most forms of the disease are due to germ line mutations of the FAS gene and manifest during the first years of life with fluctuating lymphadenopathies, hemolysis, immune thrombocytopenia. During the second decade of life disease manifestations improve spontaneously but autoimmune problems still occur and there is an increased risk of lymphoproliferative malignancy. We describe a typical case of ALPS in a now 44 year old man, followed since the age of 2 for disease manifestations that were unclear at the beginning.

  20. [Total aphasia and speech therapy: a case history (author's transl)].

    PubMed

    Birchmeier-Nussbaumer, A K

    1977-05-01

    The medical profession and therapists continue to believe that total aphasia is untreable. A case report is used to demonstrate the diagnostic features of aphasia and describe the course of the impairment from the complete loss of speech, via the learning of highly automated expressions to the aquisition of single words which the patient uses independently in the different contexts. This development involves all language functions equally. The therapy is based on conventional methods, deblocking stategies, speech therapeutic talks - principal item of the treatment - and dialogue exercises carried out under normal conditions. The problems relating to deblocking methods are discussed. A description is made of the methods which have been developed from a combined audiovisual, tactile and writing motoric speech activation programme. The article presents the linguistic signs of the syndrome in an advanced stage and demonstrates the development of the thinking structure and the psychic problems with the help of the tree drawings.

  1. History of Manuscriptology: study of medical manuscripts.

    PubMed

    Narayana, Ala

    2005-01-01

    Connoisseurs of different areas of learning are apt to hold their particular area higher above all else, as the 'Science of Sciences'. These sciences transmitted to a scholar or to a common man are known through the texts, which are either handwritten or printed. The marvel of accuracy with which the vast literature specially Vedic literature has been handed down or transmitted to us orally, from generation to generations in India carried from person to person through mouth and ear, is a matter of great admiration all early literature that is now available in printed form, originally hand written i. e. in the form of manuscripts is the basis for the learning of science and technology today. Hence, it is forced to grant a top place of honor to the science of Manuscriptology and can be considered as 'Science of Sciences'. The scripts; Writing tools; Languages; Conservation, Preservation, Maintenance of the manuscripts; the study of medical manuscripts and its constraints; the strategies to validate the old concepts, drugs, diseases, and methods of treatment hidden in the manuscripts and knowledge application in the medical science are discussed here under.

  2. [Electrical burns in children. 3 years of case histories].

    PubMed

    Caneira, E; Serafim, Z; Duarte, R; Leal, M J

    1996-01-01

    The Burn Unit of Dona Estefânia Hospital admitted a total of 454 patients from January 1992 to January 1995, 24 of these patients suffered from electric shock. Of these 24 patients 3 suffered burns in the mouth, 15 in one or both hands and 6 multiple burns. In 19 patients the burns were up to 1%. A description is made of 5 cases, male children between the ages of 9 and 13 years, which were deemed severe. The incidents occurred outdoors with different voltages and in activities considered of ludic or experimental nature: two on the roof of a house, two with railway cables and one with an electrical cable in a port zone. The burnt areas vary between 4% and 70%, all of them 2nd and 3rd degree, with hospitalization lasting from 36 to 116 days. In addition to early and coordinated medical and rehabilitative treatment, according to individual needs, a description is also made of the cutaneous sequelae (deforming cicatrices, bridles), neurologic and psychologic sequelae, with emphasis on a patient who underwent amputation of the lower left leg and 4th and 5th ranges of the right foot. It was concluded that measures should be taken in education and legislation to prevent these accidents. Relevance is given to the need for a multidisciplinary team and specialized center for the treatment of these patients.

  3. PREDICT : A CASE STUDY.

    SciTech Connect

    Kerscher, W. J. III; Booker, J. M.; Meyer, Mary A.

    2001-01-01

    Delphi Automotive Systems and the Los Alamos National Laboratory worked together to develop PREDICT, a new methodology to characterize the reliability of a new product during its development program. Rather than conducting testing after hardware has been built, and developing statistical confidence bands around the results, this updating approach starts with an early reliability estimate characterized by large uncertainty, and then proceeds to reduce the uncertainty by folding in fresh information in a Bayesian framework. A considerable amount of knowledge is available at the beginning of a program in the form of expert judgment which helps to provide the initial estimate. This estimate is then continually updated as substantial and varied information becomes available during the course of the development program. This paper presents a case study of the application of PREDICT, with the objective of further describing the methodology. PREDICT has been honored with an R&D 100 Award presented by R&D Magazine.

  4. Associations among family history of cancer, cancer screening and lifestyle behaviors: a population-based study.

    PubMed

    Bostean, Georgiana; Crespi, Catherine M; McCarthy, William J

    2013-08-01

    Some cancers are largely preventable through modification of certain behavioral risk factors and preventive screening, even among those with a family history of cancer. This study examined the associations between (1) family cancer history and cancer screening, (2) family history and cancer preventive lifestyle behaviors, and (3) cancer screening and lifestyle behaviors. Data were from the 2009 California Health Interview Survey (n = 12,603). Outcomes included screening for breast cancer (BC) and colorectal cancer (CRC) and six cancer preventive lifestyle behaviors, based on World Cancer Research Fund recommendations. Multivariate logistic regression analyses, stratified by gender and race-ethnicity, examined associations. Predicted probabilities of cancer screening by family cancer history, race-ethnicity, and sex were computed. Family history of site-specific cancer-CRC for men and women, and BC for women-was associated with higher probability of cancer screening for most groups, especially for CRC, but was largely unrelated to other lifestyle behaviors. In the few cases in which family history was significantly associated with lifestyle-for example, physical activity among White and Latino males, smoking among White and Asian females-individuals with a family history had lower odds of adherence to recommendations than those with no family history. Greater overall adherence to lifestyle recommendations was associated with higher odds of up-to-date CRC screening among White and Asian males, and lower odds among Asian females (no significant association with BC screening); this relationship did not vary by family cancer history. The fact that family history of cancer is not associated with better lifestyle behaviors may reflect shared behavioral risks within families, or the lack of knowledge about how certain lifestyle behaviors impact personal cancer risk. Findings can inform interventions aimed at lifestyle behavioral modification for individuals at increased

  5. Associations among Family History of Cancer, Cancer Screening and Lifestyle Behaviors: A Population-based Study

    PubMed Central

    Bostean, Georgiana; Crespi, Catherine M.; McCarthy, William J.

    2013-01-01

    Purpose Some cancers are largely preventable through modification of certain behavioral risk factors and preventive screening, even among those with a family history of cancer. This study examined the associations between: (1) family cancer history and cancer screening; (2) family history and cancer preventive lifestyle behaviors; and, (3) cancer screening and lifestyle behaviors. Methods Data were from the 2009 California Health Interview Survey (n=12,603). Outcomes included screening for breast cancer (BC) and colorectal cancer (CRC) and six cancer preventive lifestyle behaviors, based on World Cancer Research Fund recommendations. Multivariate logistic regression analyses, stratified by gender and race-ethnicity, examined associations. Predicted probabilities of cancer screening by family cancer history, race-ethnicity and sex were computed. Results Family history of site-specific cancer—CRC for men and women, and BC for women—was associated with higher probability of cancer screening for most groups, especially for CRC, but was largely unrelated to other lifestyle behaviors. In the few cases in which family history was significantly associated with lifestyle—e.g., physical activity among White and Latino males, smoking among White and Asian females—individuals with a family history had lower odds of adherence to recommendations than those with no family history. Greater overall adherence to lifestyle recommendations was associated with higher odds of up-to-date CRC screening among White and Asian males, and lower odds among Asian females (no significant association with BC screening); this relationship did not vary by family cancer history. Conclusions The fact that family history of cancer is not associated with better lifestyle behaviors may reflect shared behavioral risks within families, or the lack of knowledge about how certain lifestyle behaviors impact personal cancer risk. Findings can inform interventions aimed at lifestyle behavioral

  6. Serum osteoprotegerin and soluble receptor activator of nuclear factor kappaB ligand levels in patients with a history of differentiated thyroid carcinoma: a case-controlled cohort study.

    PubMed

    Giusti, Massimo; Cecoli, Francesca; Fazzuoli, Laura; De Franchis, Vincenzina; Ceresola, Enrica; Ferone, Diego; Mussap, Michele; Minuto, Francesco

    2007-05-01

    Overt hyperthyroidism is associated with changes in bone metabolism, whereas the effect of levothyroxine (L-T4) load in patients with differentiated thyroid carcinoma (DTC) is controversial. The aim of our study was to evaluate osteoprotegerin (OPG) and soluble receptor activator of nuclear factor kappaB ligand (RANK-L) in patients with DTC with suppressed endogenous thyrotropin due to L-T4 regimen. A cohort of 80 subjects with DTC (68 women and 12 men; age range, 27-81 years) was studied. A cohort of 55 subjects with a history of partial or total surgery for nonmalignant thyroid pathology served as a control group. Groups were matched for sex, age, and body mass index. Per-week dosage of L-T4 was significantly higher in patients with DTC than in controls (P < .001). More elevated free T(4) concentrations (P < .001) and more suppressed thyrotropin and thyroglobulin levels (P < .001) were found in subjects with DTC than in controls. No difference in serum or urinary parameters related to bone metabolism or dual-energy x-ray absorptiometry was noted between the groups. Overall, OPG levels were similar in both groups but were significantly (P = .03) lower in postmenopausal women with DTC than in postmenopausal control women. Only control women showed lower OPG levels in premenopausal than in postmenopausal (P = .002) conditions. Overall, RANK-L levels were significantly higher (P = .03) in subjects with DTC than in controls. In both groups, OPG and RANK-L levels were unrelated to each other. A significant positive correlation was seen between OPG levels and age in both subjects with DTC (P < .001) and controls (P < .001). Serum RANK-L correlated negatively with age in subjects with DTC (P = .05). Although there were several differences in L-T4 dosages, OPG and RANK-L levels were similar in patients with a history of DTC and those with a history of nonmalignant thyroid diseases. The correlation between circulating OPG and RANK-L levels was not significant. The increase

  7. World History Curriculum Guide: Secondary Social Studies. Bulletin 1758.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Academic Programs.

    This state curriculum guide was developed to reaffirm the importance of world history in the Louisiana social studies curriculum. It contains statements of the Louisiana social studies goals, program scopes and sequences, a list of 14 generalizations and related concepts, and a master course content outline. Seven study units are presented that…

  8. Self-Concept of Pregnant Adolescents: A Case Study.

    ERIC Educational Resources Information Center

    Elkes, Barbara Halpren; Crocitto, John A.

    1987-01-01

    Used case study approach to assess self-concepts of pregnant adolescents regarding life history, personality traits, and development. Results revealed common themes of historic background and personality traits: no intact families, lack of trust in family members, history of drug and alcohol abuse, permissive sexual attitudes and early sexual…

  9. History of Physics and Conceptual Constructions: The Case of Magnetism

    ERIC Educational Resources Information Center

    Voutsina, Lambrini; Ravanis, Konstantinos

    2011-01-01

    This study documents the mental representations of magnetism constructed by students aged 15-17 and attempts to investigate whether these display the characteristics of models with an inner cohesiveness and constancy; whether they share common features with typical historical models of the Sciences; and whether they evolve through conventional…

  10. Nanomagnetism: A Case History of Nanoscience and Technology

    ERIC Educational Resources Information Center

    Freeman, Mark

    2009-01-01

    This paper overviews the occurrence and study of magnetism on nanometer-length scales, that is, at sizes where the natural unit on a ruler would be one-billionth of a meter. Nanomagnetism has fascinating early origins on planet Earth, and we must first go back a couple billion years to get to the beginning of the story. Then we will quickly make…

  11. Sixth-Form Projects in Biology: A Case History.

    ERIC Educational Resources Information Center

    Robinson, P. M.; Parker, R. E.

    1981-01-01

    Some of the problems encountered in devising sixth-form projects are discussed and a detailed account given of one project in which a study was made of the effect of onion bulb volatiles on the germination of lettuce seed. (Author)

  12. Nanomagnetism: A Case History of Nanoscience and Technology

    ERIC Educational Resources Information Center

    Freeman, Mark

    2009-01-01

    This paper overviews the occurrence and study of magnetism on nanometer-length scales, that is, at sizes where the natural unit on a ruler would be one-billionth of a meter. Nanomagnetism has fascinating early origins on planet Earth, and we must first go back a couple billion years to get to the beginning of the story. Then we will quickly make…

  13. Sixth-Form Projects in Biology: A Case History.

    ERIC Educational Resources Information Center

    Robinson, P. M.; Parker, R. E.

    1981-01-01

    Some of the problems encountered in devising sixth-form projects are discussed and a detailed account given of one project in which a study was made of the effect of onion bulb volatiles on the germination of lettuce seed. (Author)

  14. Apollo 13 Case Study

    NASA Technical Reports Server (NTRS)

    Anderson, Brenda Lindley

    2011-01-01

    The dramatic journey of the crippled Apollo 13 vehicle has been heavily documented and popularized. Many people know there was an explosion in the service module which caused the vehicle to lose its oxygen supply. Less well known is the set of circumstances which led to the explosion. This paper examines the manufacturing, processing and testing history of oxygen tank #2, detailing the additive effects which caused the oxygen to ignite and to overpressure the tank.

  15. Life history, diversity and distribution: A study of Japanese pteridophytes

    USGS Publications Warehouse

    Guo, Q.; Kato, Masako; Ricklefs, R.E.

    2003-01-01

    Many studies address the relationships between diversity or distribution and attributes of the physical environment. However, how these relationships are connected to variation in life history is poorly understood. This is particularly true in the case of pteridophytes. Japanese ferns and their allies comprise one of the best-known pteridophyte floras in the world. We analyzed ca 600 species of Japanese pteridophytes for which there is detailed information on distribution, reproduction, and chromosome number. Species richness was greatest in groups with a single reproductive mode (sexual, followed by apogamous), but distribution was greatest in species groups with multiple reproductive modes: sexual plus either sterile (irregular in meiosis) or apogamous. Geographical ranges varied greatly among species with small chromosome numbers but were uniformly small among species having high chromosome numbers. Seasonally green (mostly summer green) species had significantly larger distribution ranges than evergreen species. Endemic species had higher proportions of apogamy and sterility than non-endemic species. Seasonally green species had significantly larger distributional ranges, and a smaller proportion of species with apogamous reproduction, than evergreen species. There was no clear relationship between distribution and spore size, either among endemic species, non-endemic species, or all species combined. There was no relationship between spore size and chromosome number when all species were combined. However, positive relationships were detected within three of the nine largest genera, suggesting potential phylogenetic effects. We concluded that habitat availability, rather than dispersability, may be the limiting factor for the distribution of pteridophytes in Japan.

  16. SURF1 deficiency: a multi-centre natural history study.

    PubMed

    Wedatilake, Yehani; Brown, Ruth M; McFarland, Robert; Yaplito-Lee, Joy; Morris, Andrew A M; Champion, Mike; Jardine, Phillip E; Clarke, Antonia; Thorburn, David R; Taylor, Robert W; Land, John M; Forrest, Katharine; Dobbie, Angus; Simmons, Louise; Aasheim, Erlend T; Ketteridge, David; Hanrahan, Donncha; Chakrapani, Anupam; Brown, Garry K; Rahman, Shamima

    2013-07-05

    SURF1 deficiency, a monogenic mitochondrial disorder, is the most frequent cause of cytochrome c oxidase (COX) deficient Leigh syndrome (LS). We report the first natural history study of SURF1 deficiency. We conducted a multi-centre case notes review of 44 SURF1-deficient patients from ten different UK centres and two Australian centres. Survival data for LRPPRC-deficient LS and nuclear-encoded complex I-deficient LS patients were obtained from previous publications. The survival of SURF1-deficient patients was compared with these two groups using Kaplan-Meier survival analysis and logrank test. The majority of patients (32/44, 73%) presented in infancy (median 9.5 months). Frequent symptoms were poor weight gain (95%, median age 10 months), hypotonia (93%, median age 14 months), poor feeding/vomiting (89%, median age 10 months), developmental delay (88%, median age 14 months), developmental regression (71%, median age 19 months), movement disorder (52%, median age 24 months), oculomotor involvement (52%, median age 29 months) and central respiratory failure (78%, median age 31 months). Hypertrichosis (41%), optic atrophy (23%), encephalopathy (20%), seizures (14%) and cardiomyopathy (2%) were observed less frequently. SURF1-deficient patients have a homogeneous clinical and biochemical phenotype. Early recognition is essential to expedite diagnosis and enable prenatal diagnosis.

  17. A Rare Case of Primary Tuberculous Tenosynovitis in a Young Patient with an Acute History.

    PubMed

    Reed, Alistair J M; Rodrigues, Jeremy N; Al-Ghazal, Sharif; Shariff, Zakir

    2017-03-01

    We present a rare case of primary tuberculous tenosynovitis in a young patient with an acute history of non-penetrating traumatic injury. The patient had recently visited Pakistan and presented with sudden onset pain at the base of their right fifth digit after trying to catch a cricket ball. A provisional diagnosis of haematoma was made; however, ultrasonography revealed a mass attached to the A2 pulley. Surgical excision followed by histological examination and culture identified Mycobacterium Tuberculosis infection. This case serves to raise clinical awareness of this rare condition and highlight the importance of obtaining a travel history.

  18. Training managers for high productivity: Guidelines and a case history

    NASA Technical Reports Server (NTRS)

    Ranftl, R. M.

    1985-01-01

    Hughes Aircrafts 13-year productivity study clearly identifies management as the key link in the entire productivity chain. This fact led to the establishment of a long-term series of seminars on personal, managerial, organizational, and operational productivity for all levels and sectors of line and staff management. To inspire the work force to higher levels of productivity and creativity management, itself, must first be inspired. In turn they have to clearly understand the productive and creative processes, fashion an effective productivity improvement plan with sound strategy and implementation, create an optimal environmental chemistry, and provide the outstanding leadership necessary to propel their organizations to achieve full potential. The primary goals of the seminars are to (1) ignite that spark of inspiration, enabling productive action to follow, (2) provide participants a credible roadmap and effective tools for implementation, and (3) develop a dedicated commitment to leadership and productivity throughout the management team.

  19. United States -- Mexican joint ventures: A case history approach

    SciTech Connect

    Moore, N.L.; Chidester, R.J.; Hughes, K.R.; Fowler, R.A.

    1993-03-01

    Because the Mexican government has encouraged investment in Mexico by increasing the percentage of ownership of a Mexican business that a US company can hold, joint ventures are more attractive now than they had been in the past. This study provides preliminary information for US renewable energy companies who are interested in forming a joint venture with a Mexican company. This report is not intended to be a complete reference but does identifies a number of important factors that should be observed when forming a Mexican joint venture: (1)Successful joint ventures achieve the goals of each partner. (2)It is essential that all parties agree to the allocation of responsibilities. (3)Put everything in writing. (4)Research in depth the country or countries in which you are considering doing business.

  20. Training managers for high productivity: Guidelines and a case history

    NASA Technical Reports Server (NTRS)

    Ranftl, R. M.

    1985-01-01

    Hughes Aircrafts 13-year productivity study clearly identifies management as the key link in the entire productivity chain. This fact led to the establishment of a long-term series of seminars on personal, managerial, organizational, and operational productivity for all levels and sectors of line and staff management. To inspire the work force to higher levels of productivity and creativity management, itself, must first be inspired. In turn they have to clearly understand the productive and creative processes, fashion an effective productivity improvement plan with sound strategy and implementation, create an optimal environmental chemistry, and provide the outstanding leadership necessary to propel their organizations to achieve full potential. The primary goals of the seminars are to (1) ignite that spark of inspiration, enabling productive action to follow, (2) provide participants a credible roadmap and effective tools for implementation, and (3) develop a dedicated commitment to leadership and productivity throughout the management team.

  1. Mathematical representations in science: a cognitive-historical case history.

    PubMed

    Tweney, Ryan D

    2009-10-01

    The important role of mathematical representations in scientific thinking has received little attention from cognitive scientists. This study argues that neglect of this issue is unwarranted, given existing cognitive theories and laws, together with promising results from the cognitive historical analysis of several important scientists. In particular, while the mathematical wizardry of James Clerk Maxwell differed dramatically from the experimental approaches favored by Michael Faraday, Maxwell himself recognized Faraday as "in reality a mathematician of a very high order," and his own work as in some respects a re-representation of Faraday's field theory in analytic terms. The implications of the similarities and differences between the two figures open new perspectives on the cognitive role of mathematics as a learned mode of representation in science. Copyright © 2009 Cognitive Science Society, Inc.

  2. Summary of SPT based field case history data of CETIN (2016) database

    USGS Publications Warehouse

    Onder Cetin, K.; Seed, Raymond B.; Kayen, Robert E.; Moss, Robb E. S.; Bilge, H. Tolga; Ilgac, Makbule; Chowdhury, Khaled

    2016-01-01

    team. A more detailed description of some of the details of the methods and procedures used to evaluate and analyze these field performance case histories is also presented in Cetin (2000) and Cetin et al. (2000) though the final evaluations presented in this report are the most recent interpretations undertaken under these current studies.

  3. The Three Domains of Conservation Genetics: Case Histories from Hawaiian Waters.

    PubMed

    Bowen, Brian W

    2016-07-01

    The scientific field of conservation biology is dominated by 3 specialties: phylogenetics, ecology, and evolution. Under this triad, phylogenetics is oriented towards the past history of biodiversity, conserving the divergent branches in the tree of life. The ecological component is rooted in the present, maintaining the contemporary life support systems for biodiversity. Evolutionary conservation (as defined here) is concerned with preserving the raw materials for generating future biodiversity. All 3 domains can be documented with genetic case histories in the waters of the Hawaiian Archipelago, an isolated chain of volcanic islands with 2 types of biodiversity: colonists, and new species that arose from colonists. This review demonstrates that 1) phylogenetic studies have identified previously unknown branches in the tree of life that are endemic to Hawaiian waters; 2) population genetic surveys define isolated marine ecosystems as management units, and 3) phylogeographic analyses illustrate the pathways of colonization that can enhance future biodiversity. Conventional molecular markers have advanced all 3 domains in conservation biology over the last 3 decades, and recent advances in genomics are especially valuable for understanding the foundations of future evolutionary diversity. © The American Genetic Association. 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. The Ecology of Sustainable Implementation: Reflection on a 10-Year Case History Illustration.

    PubMed

    Rimehaug, Tormod

    2014-01-01

    The primary aim of this paper is to illustrate the strategic and ecological nature of implementation. The ultimate aim of implementation is not dissemination but sustainability beyond the implementation effort. A case study is utilized to illustrate these broad and long-term perspectives of sustainable implementation based on qualitative analyses of a 10-year implementation effort. The purveyors aimed to develop selective community prevention services for children in families burdened by parental psychiatric or addictive problems. Services were gradually disseminated to 23 sites serving 40 municipalities by 2013. Up to 2013, only one site terminated services after initial implementation. Although many sites suspended services for shorter periods, services are still offered at 22 sites. This case analysis is based on project reports, user evaluations, practitioner interviews, and service statistics. The paper focuses on the analyses and strategies utilized to cope with quality decay and setbacks as well as progress and success in disseminating and sustaining the services and their quality. Low-cost multilevel strategies to implement services at the community level were organized by a prevention unit in child psychiatry, supervised by a university department (purveyors). The purveyors were also involved in national and international collaboration and development. Multilevel strategies included manualized intervention, in-practice training methods, organizational responsibility, media strategies, service evaluation, staff motivation maintenance, quality assurance, and proposals for new law regulations. These case history aspects will be discussed in relation to the implementation literature, focusing on possible applicability across settings.

  5. Geophysics with applications to subsurface waste disposal: Case history

    SciTech Connect

    Lee, K.H.

    2001-08-09

    Recent development in geophysical methods allows us to accurately map the distribution of seismic velocity, density and electrical conductivity beneath the surface and between boreholes. These physical properties are dependent on porosity, fluid saturation, fluid conductivity, pressure, temperature, clay content, and in some circumstances, permeability. Hydrological parameters may be measured or inferred from drill hole experiments or directly from core samples. The point measurements in a drill hole are then interpolated to the interwell volume using either statistical properties of the local geology or reasonable estimates of the geological structure and lithology. More direct evidence is obtained from well tests, and interference tests between multiple wells, but these are ill posed inverse problems when it comes to defining the properties of the entire interwell volume. Furthermore such tests are impossible in the vadose zone. The interpolation of well data is often inaccurate or misleading and the central problem for all these studies is the lack of these fundamental parameters throughout the subsurface volume of interest.

  6. In situ diesel fuel bioremediation: A case history

    SciTech Connect

    Rhodes, D.K.; Burke, G.K.; Smith, N.; Clark, D.

    1995-12-31

    As a result of a ruptured fuel line, the study site had diesel fuel soil contamination and free product more than 2 ft (0.75 m) thick on the groundwater surface. Diesel fuel, which is composed of a high percentage of nonvolatile compounds, has proven difficult to remediate using conventional extraction remediation techniques. A number of remedial alternatives were reviewed, and the patented in situ biodegradation BioSparge{sup SM} technology was selected for the site and performed under license by a specialty contractor. BioSparge{sup SM} is a field-proven closed-loop (no vapor emissions) system that supplies a continuous, steady supply of oxygen, moisture, and additional heat to enhance microorganism activity. The system injects an enriched airstream beneath the groundwater surface elevation and/or within the contaminant plume and removes residual vapors from vadose zone soil within and above the contaminant plume. The technology has no air discharge, which is critical in areas where strict air discharge regulations apply. The focus of this paper is the viability of in situ biodegradation as an effective remediation alternative for reducing nonvolatile petroleum products.

  7. History or Social Studies? Frying Pan or Fire.

    ERIC Educational Resources Information Center

    English, Raymond

    Social studies as taught in many schools is anti-intellectual, formless, and ineffective. History, if properly taught, is at the opposite extreme: challenging to the point of being beyond the comprehension of young students. Social studies at its worst is experimental psychological manipulation. At its best it can be a useful synthesis of concepts…

  8. Toward Systematic Study of the History and Foundations of Literacy

    ERIC Educational Resources Information Center

    King, James R.; Stahl, Norman A.

    2012-01-01

    This study of a literacy course begins with methodological approaches useful in the historical study of the literacy profession, its practices, beliefs, and participants. A model course is presented via "moments" in the history of literacy. Results from implementations of the model course are also presented.

  9. Women's Studies in Australian Higher Education: Introduction and Brief History.

    ERIC Educational Resources Information Center

    Ryan, Lyndall

    1991-01-01

    The history of women's studies in Australian universities is reviewed from 1973 to the present. Three phases are identified: phase one 1972-82: revolutionary feminism versus liberal feminism; phase two 1983-88: development of academic feminism; and phase three 1989-91: women's studies in the post-Dawkins era. (DB)

  10. Dioxin: a case study.

    PubMed

    Bond, G G

    1993-01-01

    The need to notify individuals of a possible health risk from their past exposure to potentially hazardous agents frequently extends beyond workers to include community groups. The issues to consider in community notification are frequently similar to those that are important for worker notification but may include some that are unique. This case study traces the evolution of one company's strategy for communicating with the public about possible dioxin contamination associated with its operations. Early communications tended to emphasize the technical aspects of the issues in the fashion of scientists talking to other scientists. This was interpreted by some to be symptomatic of an arrogant and uncaring attitude. Beginning in the early 1980s, the company's management recognized the need to reach out to a variety of audiences on multiple levels, and shifted to a more comprehensive communications strategy. A similar shift is now occurring throughout the chemical manufacturing industry as top managers realize that, if they expect to continue to operate, they must become more accountable and responsive to the public.

  11. Natural Learning Case Study Archives

    ERIC Educational Resources Information Center

    Lawler, Robert W.

    2015-01-01

    Natural Learning Case Study Archives (NLCSA) is a research facility for those interested in using case study analysis to deepen their understanding of common sense knowledge and natural learning (how the mind interacts with everyday experiences to develop common sense knowledge). The database comprises three case study corpora based on experiences…

  12. Natural Learning Case Study Archives

    ERIC Educational Resources Information Center

    Lawler, Robert W.

    2015-01-01

    Natural Learning Case Study Archives (NLCSA) is a research facility for those interested in using case study analysis to deepen their understanding of common sense knowledge and natural learning (how the mind interacts with everyday experiences to develop common sense knowledge). The database comprises three case study corpora based on experiences…

  13. The Paradox of Case Study.

    ERIC Educational Resources Information Center

    Simons, Helen

    1996-01-01

    Examines the paradox of case studies' abilities to understand the complexity in particular contexts while not being generalizable. Argues that the pressure for quantification and multisite case study design in policy research has weakened the original utility of the case study method for understanding complex educational phenomena. (DSK)

  14. Interrupting History: Rethinking History Curriculum after "The End of History". Counterpoints: Studies in the Postmodern Theory of Education. Volume 404

    ERIC Educational Resources Information Center

    Parkes, Robert John

    2011-01-01

    Since the emergence of postmodern social theory, history has been haunted by predictions of its imminent end. Postmodernism has been accused of making historical research and writing untenable, encouraging the proliferation of revisionist histories, providing fertile ground for historical denial, and promoting the adoption of a mournful view of…

  15. Interrupting History: Rethinking History Curriculum after "The End of History". Counterpoints: Studies in the Postmodern Theory of Education. Volume 404

    ERIC Educational Resources Information Center

    Parkes, Robert John

    2011-01-01

    Since the emergence of postmodern social theory, history has been haunted by predictions of its imminent end. Postmodernism has been accused of making historical research and writing untenable, encouraging the proliferation of revisionist histories, providing fertile ground for historical denial, and promoting the adoption of a mournful view of…

  16. CASE HISTORY OF FINE PORE DIFFUSER RETROFIT AT RIDGEWOOD, NEW JERSEY

    EPA Science Inventory

    In April 1983, the Ridgewood, New Jersey Wastewater Treatment Plant underwent a retrofit from a coarse bubble to a fine pore aeration system. Also, process modification from contact stabilization to tapered aeration occurred. This report presents a case history of plant and aer...

  17. Four Case Histories and a Literature Review of Williams Syndrome and Autistic Behavior.

    ERIC Educational Resources Information Center

    Gillberg, Christopher; Rasmussen, Peder

    1994-01-01

    This paper summarizes the case histories of four young children with concurrent autistic disorder and Williams syndrome. Williams syndrome comprises a peculiar facial appearance, learning disorder, and often hypercalcemia, mild microcephaly, large blood vessel stenosis, and a specific behavioral phenotype. Literature on Williams syndrome is…

  18. CASE HISTORY OF FINE PORE DIFFUSER RETROFIT AT RIDGEWOOD, NEW JERSEY

    EPA Science Inventory

    In April 1983, the Ridgewood, New Jersey Wastewater Treatment Plant underwent a retrofit from a coarse bubble to a fine pore aeration system. Also, process modification from contact stabilization to tapered aeration occurred. This report presents a case history of plant and aer...

  19. Four Case Histories and a Literature Review of Williams Syndrome and Autistic Behavior.

    ERIC Educational Resources Information Center

    Gillberg, Christopher; Rasmussen, Peder

    1994-01-01

    This paper summarizes the case histories of four young children with concurrent autistic disorder and Williams syndrome. Williams syndrome comprises a peculiar facial appearance, learning disorder, and often hypercalcemia, mild microcephaly, large blood vessel stenosis, and a specific behavioral phenotype. Literature on Williams syndrome is…

  20. Case-Control Study: Smoking History Affects the Production of Tumor Antigen-Specific Antibodies NY-ESO-1 in Patients with Lung Cancer in Comparison with Cancer Disease-Free Group.

    PubMed

    Myšíková, Dagmar; Adkins, Irena; Hradilová, Nad'a; Palata, Ondřej; Šimonek, Jan; Pozniak, Jiří; Kolařík, Jan; Skallová-Fialová, Anna; Špíšek, Radek; Lischke, Robert

    2017-02-01

    Lung cancer is the leading cause of cancer mortality worldwide; therefore, understanding the biological or clinical role of tumor-associated antigens and autoantibodies is of eminent interest for designing antitumor immunotherapeutic strategies. Here we prospectively analyzed the serum frequencies of New York esophageal squamous cell carcinoma 1 (NY-ESO-1), human epidermal growth factor 2/neu, and melanoma-associated antigen A4 (MAGE-A4) antibodies and expression of the corresponding antigens in tumors of 121 patients with NSCLC undergoing an operation without prior neoadjuvant chemotherapy and compared them with those in 57 control age-matched patients with no history of a malignant disease. We found that only antibodies specific for NY-ESO-1 (19.8% [n = 24 of 121]) were significantly increased in the group of patients with NSCLC compared with in the controls. NY-ESO-1 seropositivity was significantly positively associated with an active smoking history in patients with NSCLC but not in smokers from the control group. In tumors, the frequency of NY-ESO-1 mRNA expression was 6.3% (in four of 64 patients), the frequency of human epidermal growth factor 2/neu (HER 2/neu) expression was 11.9% (five of 42), and the frequency of MAGE-A4 expression was 35.1% (20 of 57). MAGE-A4 expression in tumors correlated with smoking status and male sex in patients with NSCLC. Patients with squamous cell carcinoma displayed higher expression of NY-ESO-1 and MAGE-A4 in tumors than did patients with adenocarcinoma. On the other hand, 94.7% of nonsmoking patients in our study had adenocarcinoma (of whom 73.7% were women). These results confirm the reported high immunogenicity of NY-ESO-1 and suggest that a smoking-induced chronic inflammatory state might potentiate the development of NY-ESO-1-specific immune responses. Moreover, smoking might contribute to the expression of other cancer/testis antigens such as MAGE-A4 at early stages of NSCLC development. Copyright © 2016

  1. A Study of Work Histories of Married Nurses.

    ERIC Educational Resources Information Center

    Willis, Lucy Dorothea

    This study dealt with married women as past, present, and future members of the nursing force. Respondents were 53 married women, aged 22 to 68, in the Moose Jaw, Saskatchewan, Health Region who had been registered nurses. Data were gathered on personal, family, and work history, motives for entering the nursing profession, and satisfactions and…

  2. Decoding the Social Studies Production of Chicano History.

    ERIC Educational Resources Information Center

    Arries, Jonathan F.

    1994-01-01

    Analyzes in two fifth-grade social studies textbooks, the production of three "foundation myths" relating to Chicanos in American history: (1) Texas independence and the Alamo, (2) the Mexican War, and (3) the 20-century struggle for civil rights. How these contribute to cultural degradation is discussed. (SLD)

  3. The Multi-Disciplinary Approach in History and Ethnic Studies.

    ERIC Educational Resources Information Center

    Balogh, Sandor

    1980-01-01

    Considers the fractionalization of the social science disciplines indicating that this clear delineation of intellectual territory is important to research, but that in information assimilation and dissemination an interdisciplinary approach is more appropriate. Recommends two approaches to interdisciplinary studies based around history and ethnic…

  4. Rett syndrome diagnostic criteria: Lessons from the Natural History Study

    USDA-ARS?s Scientific Manuscript database

    Analysis of 819 participants enrolled in the Rett syndrome (RTT) Natural History Study, validates recently revised diagnostic criteria. Seven hundred sixty-five females fulfilled 2002 consensus criteria for classic (653/85.4%) or variant (112/14.6%) RTT. All participants classified as classic RTT fu...

  5. Connecticut Curriculum Trace Maps: History/Social Studies.

    ERIC Educational Resources Information Center

    Connecticut State Board of Education, Hartford.

    These Connecticut Curriculum Trace Maps are designed to help curriculum developers and teachers translate Connecticut's K-12 history and social studies performance standards into objectives and classroom practice. The Trace Maps provide detailed descriptions of what students should know and be able to do at smaller grade level clusters, K-2, 3-4,…

  6. Human Rights and History Education: An Australian Study

    ERIC Educational Resources Information Center

    Burridge Nina; Buchanan, John; Chodkiewicz, Andrew

    2014-01-01

    The place of education for and about human rights within the school curriculum remains contested and this paper reports on the first national cross-sectoral investigation of its place in Australian curricula and more specifically in national and state History curriculum documents. Opportunities for the inclusion of human rights based studies were…

  7. How to Teach Thinking Skills in Social Studies and History

    ERIC Educational Resources Information Center

    Beyer, Barry K.

    2008-01-01

    This article presents four guidelines for providing direct instruction in thinking skills in social studies and history at any grade level. The author first describes, with examples, three major components of any thinking skill that students need to know. Second, he presents teaching techniques for making these components explicit. Third, he…

  8. A Study about Using Internet in History Lessons

    ERIC Educational Resources Information Center

    Ulusoy, Kadir

    2012-01-01

    Internet has become an important part in the field of education as it is in every area nowadays as well. Internet has become appealing among educators and students with its easy and quick access and wide opportunities. In this study, an application of using internet in the history course was done. 160 students who were enrolled in College of…

  9. A Study about Using Internet in History Lessons

    ERIC Educational Resources Information Center

    Ulusoy, Kadir

    2012-01-01

    Internet has become an important part in the field of education as it is in every area nowadays as well. Internet has become appealing among educators and students with its easy and quick access and wide opportunities. In this study, an application of using internet in the history course was done. 160 students who were enrolled in College of…

  10. Women and History: Bibliography. Women's Studies: Potentialities and Implications.

    ERIC Educational Resources Information Center

    Laurel, Jeanne P., Comp.

    The amount of information available on Women's Studies has increased dramatically over the past two decades. Therefore, a brief bibliography of texts which focuses on women and history has been compiled. The items are grouped under the following headings: articles (published in a journal), bibliographies (including teaching guides and sources to…

  11. Teaching Pharmacology by Case Study.

    ERIC Educational Resources Information Center

    Jordan, Sue

    1997-01-01

    Using pharmacology case studies with nursing students encourages theory-practice links and infuses real-life content. Cases provide rich qualitative data for evaluating curriculum. However, they are not a substitute for evidence-based practice. (SK)

  12. Case study--leprosy.

    PubMed

    Wood, A M; Wood, C M; Bakker-Dyos, J

    2010-01-01

    We present the case of a 26 year old Indian base worker who attended the Role 2 enhanced hospital in Iraq with a case of leprosy. The patient presented four times over a 12 month period with non-specific pain in the right hand and forearm combined with a large lesion of dry skin and reduced sensation in the forearm. A clinical diagnosis of leprosy was made, which was subsequently confirmed as paucibacillary leprosy by skin smears sent to the UK. It was not possible to treat the patient locally and a recommendation made to the patient's employer that the patient return to India to commence treatment.

  13. Using the Case Study Method in Teaching College Physics

    ERIC Educational Resources Information Center

    Burko, Lior M.

    2016-01-01

    The case study teaching method has a long history (starting at least with Socrates) and wide current use in business schools, medical schools, law schools, and a variety of other disciplines. However, relatively little use is made of it in the physical sciences, specifically in physics or astronomy. The case study method should be considered by…

  14. Using the Case Study Method in Teaching College Physics

    ERIC Educational Resources Information Center

    Burko, Lior M.

    2016-01-01

    The case study teaching method has a long history (starting at least with Socrates) and wide current use in business schools, medical schools, law schools, and a variety of other disciplines. However, relatively little use is made of it in the physical sciences, specifically in physics or astronomy. The case study method should be considered by…

  15. Food and History: Teaching Social History Through the Study of Cuisine Patterns

    ERIC Educational Resources Information Center

    Gordon, Bertram M.

    1974-01-01

    Some interesting relationships between food and history -- working women and convenience food, exploration and the importation of new vegetables, reliance on potatoes and Irish emigration -- are suggested to indicate the usefulness of exploring history through eating habits. (JH)

  16. Food and History: Teaching Social History Through the Study of Cuisine Patterns

    ERIC Educational Resources Information Center

    Gordon, Bertram M.

    1974-01-01

    Some interesting relationships between food and history -- working women and convenience food, exploration and the importation of new vegetables, reliance on potatoes and Irish emigration -- are suggested to indicate the usefulness of exploring history through eating habits. (JH)

  17. Performable Case Studies in Ethics Education.

    PubMed

    Robeson, Richard; King, Nancy M P

    2017-09-12

    Bioethics education often includes the study of short stories, novels, plays, and films, because such materials present case examples that can highlight relevant issues and questions especially vividly for a wide range of students. In addition, creative writing is widely used in the education of health professional students and in continuing education settings for health professionals. There are very few academic or professional disciplines that do not use case studies, but the case study in dialogic form has not been standard practice for thousands of years. Dramatic arts casuistry-the creation and performance of short case studies designed specifically to raise bioethics issues for discussion-represents an application of literature and the medical humanities that is both unique and uniquely valuable. This essay describes the development and history of a course that has been successfully taught to medical students and graduate bioethics students, in which the class researches, writes, and performs a case study designed to elicit reflection and discussion about a topic and set of bioethics issues of current interest to both academic and general audiences. The model is also suited to the presentation and discussion of existing case studies, both live and via on-demand audio.

  18. Two new cases of liver angiosarcoma: history and perspectives of liver angiosarcoma among plastic industry workers.

    PubMed

    Hozo, I; Andelinović, S; Ljutić, D; Bojić, L; Mirić, D; Giunio, L

    1997-01-01

    In this report of two new cases of liver angiosarcoma (ASL) among plastic industry workers, the authors present the history and perspectives of this problem. The first cases of ASL have been registered since 1974, and in 1984, the European register of angiosarcoma was founded. In this register, 11 cases of ASL and one case of haemangiopericytoma have been registered from Croatia, all from a single plastics plant near Split. Two new cases of ASL (in retired autoclave cleaners, who were exposed to a concentration of 500-1000 ppm vinyl chloride monomer (VCM) during the working process) in the same plant are represented. They were detected with combined techniques of ASL detection, and both are still alive. The diagnoses have been histologically confirmed: one of them was surgically treated with segmental liver resection. The appearance of new cases of ASL confirms the perspective presented in the last report by the same authors.

  19. Lead poisoning: case studies.

    PubMed

    Gordon, J N; Taylor, A; Bennett, P N

    2002-05-01

    Early clinical features of lead toxicity are non-specific and an occupational history is particularly valuable. Lead in the body comprises 2% in the blood (t1/2 35 days) and 95% in bone and dentine (t1/2 20-30 years). Blood lead may remain elevated for years after cessation from long exposure, due to redistribution from bone. Blood lead concentration is the most widely used marker for inorganic lead exposure. Zinc protoporphyrin (ZPP) concentration in blood usefully reflects lead exposure over the prior 3 months. Symptomatic patients with blood lead concentration >2.4 micromol l-1 (50 microg dl-1) or in any event >3.8 micromol l-1 (80 microg dl-1) should receive sodium calciumedetate i.v., followed by succimer by mouth for 19 days. Asymptomatic patients with blood lead concentration >2.4 micromol l-1 (50 microg dl-1) may be treated with succimer alone. Sodium calciumedetate should be given with dimercaprol to treat lead encephalopathy.

  20. Nodular glomerulosclerosis in patients’ without history of diabetes mellitus: a case report

    PubMed Central

    Goucha, Rym; Karoui, Cyrine; Abderrahim, Ezzedine; Hamida, Fethi Ben; Elyounsi, Fethi; Maiz, Hedi Ben; Abdallah, Taieb Ben; Kheder, Adel

    2009-01-01

    Introduction Diabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus. The characteristic lesions are diffuse or nodular (Kimmelsteil-Wilson) diabetic glomerulosclerosis. The reported cases represent unusual presentations of diabetes mellitus. Case presentation We report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes. Conclusion Renal manifestations of diabetes mellitus may antedate other more common presenting symptoms of this disease and we critically review the literature on this subject. PMID:19918545

  1. Emotion, Engagement, and Case Studies

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman; Terry, David R.; Lemons, Paula; Armstrong, Norris; Brickman, Peggy; Ribbens, Eric

    2014-01-01

    Three college faculty taught large general biology classes using case studies and personal response systems (clickers). Each instructor taught the same eight cases in two different sections, except the questions within the cases differed. In one section the questions were lower order (LO) factual inquiries, and in the other they were largely…

  2. Emotion, Engagement, and Case Studies

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman; Terry, David R.; Lemons, Paula; Armstrong, Norris; Brickman, Peggy; Ribbens, Eric

    2014-01-01

    Three college faculty taught large general biology classes using case studies and personal response systems (clickers). Each instructor taught the same eight cases in two different sections, except the questions within the cases differed. In one section the questions were lower order (LO) factual inquiries, and in the other they were largely…

  3. History Electives in High School: Making Social Studies Engaging

    ERIC Educational Resources Information Center

    Kelsey, Sean

    2011-01-01

    The majority of public high school students in California are missing out on history. Many students may not see it that way, but that is because they have little understanding of what it means to appreciate history. The traditional high school history survey courses, US History and world history, provide an overview of "everything that ever…

  4. Tsetsaut History: The Forgotten Tribe of Southern Southeast Alaska. Portland Canal Early History (Misty Fiord National Monument). Alaska Historical Commission Studies in History #147.

    ERIC Educational Resources Information Center

    Dangeli, Reginald H.

    Written by one of the tribe's few remaining members and based on oral history and legend, this study traces the history of the Tsetsaut tribe, ancient original inhabitants of the Portland Canal area of southeastern Alaska. Chapters recount the quest for the coast, legends of Portland Canal, exploration of the area, material culture, establishment…

  5. Reusable experiment controllers, case studies

    NASA Astrophysics Data System (ADS)

    Buckley, Brian A.; Gaasbeck, Jim Van

    1996-03-01

    Congress has given NASA and the science community a reality check. The tight and ever shrinking budgets are trimming the fat from many space science programs. No longer can a Principal Investigator (PI) afford to waste development dollars on re-inventing spacecraft controllers, experiment/payload controllers, ground control systems, or test sets. Inheritance of the Ground Support Equipment (GSE) from one program to another is not a significant re-use of technology to develop a science mission in these times. Reduction of operational staff and highly autonomous experiments are needed to reduce the sustaining cost of a mission. The re-use of an infrastructure from one program to another is needed to truly attain the cost and time savings required. Interface and Control Systems, Inc. (ICS) has a long history of re-usable software. Navy, Air Force, and NASA programs have benefited from the re-use of a common control system from program to program. Several standardization efforts in the AIAA have adopted the Spacecraft Command Language (SCL) architecture as a point solution to satisfy requirements for re-use and autonomy. The Environmental Research Institute of Michigan (ERIM) has been a long-standing customer of ICS and are working on their 4th generation system using SCL. Much of the hardware and software infrastructure has been re-used from mission to mission with little cost for re-hosting a new experiment. The same software infrastructure has successfully been used on Clementine, and an end-to-end system is being deployed for the Far Ultraviolet Spectroscopic Explorer (FUSE) for Johns Hopkins University. A case study of the ERIM programs, Clementine and FUSE will be detailed in this paper.

  6. On the Psychometric Study of Human Life History Strategies.

    PubMed

    Richardson, George B; Sanning, Blair K; Lai, Mark H C; Copping, Lee T; Hardesty, Patrick H; Kruger, Daniel J

    2017-01-01

    This article attends to recent discussions of validity in psychometric research on human life history strategy (LHS), provides a constructive critique of the extant literature, and describes strategies for improving construct validity. To place the psychometric study of human LHS on more solid ground, our review indicates that researchers should (a) use approaches to psychometric modeling that are consistent with their philosophies of measurement, (b) confirm the dimensionality of life history indicators, and (c) establish measurement invariance for at least a subset of indicators. Because we see confirming the dimensionality of life history indicators as the next step toward placing the psychometrics of human LHS on more solid ground, we use nationally representative data and structural equation modeling to test the structure of middle adult life history indicators. We found statistically independent mating competition and Super-K dimensions and the effects of parental harshness and childhood unpredictability on Super-K were consistent with past research. However, childhood socioeconomic status had a moderate positive effect on mating competition and no effect on Super-K, while unpredictability did not predict mating competition. We conclude that human LHS is more complex than previously suggested-there does not seem to be a single dimension of human LHS among Western adults and the effects of environmental components seem to vary between mating competition and Super-K.

  7. A Case of Skin Picking Disorder of a Patient with a History of Childhood Abuse

    PubMed Central

    OKAN İBİLOĞLU, Aslıhan; ATLI, Abdullah; KAYA, Mehmet Cemal; DEMİR, Süleyman; BULUT, Mahmut; SIR, Aytekin

    2016-01-01

    Skin picking (excoriation) disorder is the recurrent excoriation of one’s own skin, resulting in noticeable skin damage. People pick their skin for different reasons. For the majority of patients, first skin picking is associated with a history of childhood abuse and personal problems. Subjects who moderately to severely cause injurious self-harm are more likely to have a history of exposure to domestic violence and childhood abuse than those who do not self-harm. At the same time, these conditions could be related to the etiology for majority of other psychiatric disorders. We report herein, a case of a patient with skin picking disorder who had a history of childhood physical and emotional abuse with borderline personality disorder. PMID:28360794

  8. A Case of Skin Picking Disorder of a Patient with a History of Childhood Abuse.

    PubMed

    Okan Ibiloğlu, Aslıhan; Atli, Abdullah; Kaya, Mehmet Cemal; Demir, Süleyman; Bulut, Mahmut; Sir, Aytekin

    2016-06-01

    Skin picking (excoriation) disorder is the recurrent excoriation of one's own skin, resulting in noticeable skin damage. People pick their skin for different reasons. For the majority of patients, first skin picking is associated with a history of childhood abuse and personal problems. Subjects who moderately to severely cause injurious self-harm are more likely to have a history of exposure to domestic violence and childhood abuse than those who do not self-harm. At the same time, these conditions could be related to the etiology for majority of other psychiatric disorders. We report herein, a case of a patient with skin picking disorder who had a history of childhood physical and emotional abuse with borderline personality disorder.

  9. Case Study: Case Studies and the Flipped Classroom

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman; Schiller, Nancy A.

    2013-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses the positive and negative aspects of the "flipped classroom." In the flipped classroom model, what is normally done in class and what is normally done as…

  10. Case Study: Case Studies and the Flipped Classroom

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman; Schiller, Nancy A.

    2013-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses the positive and negative aspects of the "flipped classroom." In the flipped classroom model, what is normally done in class and what is normally done as…

  11. [The trend and prospect of studies of East Asian medical history in Korea].

    PubMed

    Sihn, Kyuhwan

    2010-06-30

    Studies of East Asian medical history in Korea have progressively accumulated in the last twenty years. First, Korean scholars broadened the focus of research from China-centered research to East Asian research. Studies of Toyo medical history in Korea mainly concentrated on Chinese medical history. Toyo medical history originated from Japanese orientalism and imperialism. Today the studies of East Asian medical history in Korea include Korea, China and Japan, and attempt to deal with East Asia as a single conceptual category. Second, researchers in East Asian medical history are steadily increasing. They study Chinese medical history or Japanese medical history from universities. As they continue their research in academic positions, successive researchers emerge. Third, the number of Korean scholars remains relatively small, but they pursue original research. Their interests are in the discourse of East Asian medical history, colonial modernity, environmental history, oral history, and history of disease.

  12. U.S.-Japan Relations: The View from Both Sides of the Pacific. Part I, Episodes in the History of U.S.-Japan Relations: Case Studies of Conflict, Conflict Management & Resolution.

    ERIC Educational Resources Information Center

    Mukai, Gary

    This curriculum unit is the first part of a three-part series; it focuses on the theme of conflict. It introduces students to conflict on personal, group, international, and global levels and to basic conflict resolution/management alternatives. Students learn about six categories of conflict through the analysis of episodes in the history of…

  13. U.S.-Japan Relations: The View from Both Sides of the Pacific. Part I, Episodes in the History of U.S.-Japan Relations: Case Studies of Conflict, Conflict Management & Resolution.

    ERIC Educational Resources Information Center

    Mukai, Gary

    This curriculum unit is the first part of a three-part series; it focuses on the theme of conflict. It introduces students to conflict on personal, group, international, and global levels and to basic conflict resolution/management alternatives. Students learn about six categories of conflict through the analysis of episodes in the history of…

  14. Case report: clearance to dive for a naval candidate with family history of malignant hyperthermia.

    PubMed

    Vigilante, John A

    2013-01-01

    A 20-year-old male military recruit who presented for a screening physical for U.S.Naval Diving Duty was found to have family history significant for malignant hyperthermia. He had never been exposed to anesthesia, a trigger for the condition, and had not undergone testing. Medical history was otherwise unremarkable, and the patient was cleared for diving. Literature search was conducted using PubMed/Medline. Keywords included malignant hyperthermia, exertional heat illness, exertional rhabdomyolysis, diving, special operations, military. Results that included cases of malignant hyperthermia were included. Review of the literature reveals that malignant hyperthermia is primary a pharmacogenetic disorder limited to specific anesthetics, with rare reports of environmental triggers. Analysis of the disease, as well as the absence of reported cases of malignant hyperthermia in diving, suggest there is minimal increased risk in diving for subjects without history of exercise intolerance. Individuals with presumed or proven malignant hyperthermia susceptibility seeking activity clearance should be given precautions and undergo careful questioning for history of heat- or exercise-related illness. If negative, it seems reasonable to allow the patient participation in recreational or technical diving.

  15. Gulf of Mexico Climate-History Calibration Study

    USGS Publications Warehouse

    Spear, Jessica W.; Poore, Richard Z.

    2010-01-01

    Reliable instrumental records of past climate are available for about the last 150 years only. To supplement the instrumental record, reconstructions of past climate are made from natural recorders such as trees, ice, corals, and microfossils preserved in sediments. These proxy records provide information on the rate and magnitude of past climate variability, factors that are critical to distinguishing between natural and human-induced climate change in the present. However, the value of proxy records is heavily dependent on calibration between the chemistry of the natural recorder and of the modern environmental conditions. The Gulf of Mexico Climate and Environmental History Project is currently undertaking a climate-history calibration study with material collected from an automated sediment trap. The primary focus of the calibration study is to provide a better calibration of low-latitude environmental conditions and shell chemistry of calcareous microfossils, such as planktic Foraminifera.

  16. Diagnosis of penicillin allergy revisited: the value of case history, skin testing, specific IgE and prolonged challenge.

    PubMed

    Hjortlund, J; Mortz, C G; Skov, P S; Bindslev-Jensen, C

    2013-08-01

    Skin testing in duplicate, correlation between case history of immediate and nonimmediate reactions and challenge outcome and prolonged oral treatment with penicillin in the diagnostic evaluation of allergic reactions to β-lactam antibiotics, mimicking real-life situations, have only been addressed in few studies. A total of 342 patients suspected of having β-lactam allergy were investigated according to the European Network for Drug Allergy (ENDA) guidelines and patients found to be negative in the ENDA program were supplemented with a 7-day oral treatment with penicillin. Skin testing with penicillins was performed in duplicate. Patients with case histories of reactions to other β-lactams were also subsequently challenged with the culprit drug. Nineteen patients were IgE-sensitized to penicillin. Then, intracutaneous tests (ICTs) were performed, in which 35 patients tested positive for allergy, 21 with delayed and 14 with immediate reactions. Only three patients tested positive for the major (PPL) and/or minor (MDM) penicillin determinants, all being positive for penicillin G in ICT. The remaining 291 patients were challenged with penicillin: 10 tested positive in single-dose challenge and 23 tested positive in the 7-day challenge. A total of 17 of 78 patients with a negative penicillin challenge tested positive during challenges with other β-lactams. We found no correlation between case histories of immediate and nonimmediate reactions and reaction time during challenge. The data suggest that case history is often insufficient to discriminate between immediate reactors and nonimmediate reactors. A 7-day challenge with the culprit β-lactam may yield more positive reactions than the accepted one- or 2-day challenge. Interpretation of skin testing should be made with caution. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. THE JEWS IN AMERICAN HISTORY--A RESOURCE BOOK FOR TEACHERS OF SOCIAL STUDIES AND AMERICAN HISTORY.

    ERIC Educational Resources Information Center

    HARTSTEIN, JACOB I.

    A RESOURCE BOOK, PROVIDING AMERICAN HISTORY AND SOCIAL STUDIES TEACHERS WITH APPROPRIATE INFORMATION ABOUT THE PAST AND PRESENT OF JEWS IN AMERICA, IS PRESENTED. THE INFORMATION CAN BE USED IN CONNECTION WITH PROGRAMS, UNITS, AND COURSES IN HISTORY AND INTERCULTURAL EDUCATION. THE FIRST SECTION GIVES AN HISTORIC ACCOUNT OF DIFFERENT PERIODS IN…

  18. THE JEWS IN AMERICAN HISTORY--A RESOURCE BOOK FOR TEACHERS OF SOCIAL STUDIES AND AMERICAN HISTORY.

    ERIC Educational Resources Information Center

    HARTSTEIN, JACOB I.

    A RESOURCE BOOK, PROVIDING AMERICAN HISTORY AND SOCIAL STUDIES TEACHERS WITH APPROPRIATE INFORMATION ABOUT THE PAST AND PRESENT OF JEWS IN AMERICA, IS PRESENTED. THE INFORMATION CAN BE USED IN CONNECTION WITH PROGRAMS, UNITS, AND COURSES IN HISTORY AND INTERCULTURAL EDUCATION. THE FIRST SECTION GIVES AN HISTORIC ACCOUNT OF DIFFERENT PERIODS IN…

  19. Excessive yawning and thermoregulation: two case histories of chronic, debilitating bouts of yawning.

    PubMed

    Gallup, Gordon G; Gallup, Andrew C

    2010-06-01

    This report details the case histories of two women who suffer from chronic and debilitating episodes of excessive yawning in the absence of sleep problems. Each woman independently provided information and answered questions about their excessive yawning symptoms and medical histories. Both women show signs of thermoregulatory dysfunction, and each reports symptom relief and/or the postponement of yawning attacks through means of behavioral cooling. One woman recorded her body temperature before and after bouts of yawning, revealing a significant drop in temperature following each episode (p < 0.05). The trigger for yawning in these patients appears to be related to increases in body/brain temperature. These cases are consistent with growing evidence showing that recurrent episodes of excessive yawning are not necessarily associated with a sleep disorder, but rather may be indicative of thermoregulatory dysfunction.

  20. Nanomaterial Case Study: A Comparison of Multiwalled ...

    EPA Pesticide Factsheets

    The draft document is intended to be used as part of a process to identify what is known and, more importantly, what is not yet known that could be of value in assessing the broad implications of specific nanomaterials. Like previous case studies (see History/ Chronology below), this draft case study on multiwalled carbon nanotubes (MWCNTs) is based on the comprehensive environmental assessment (CEA) approach, which consists of both a framework and a process. Unlike previous case studies this case study incorporates information about a traditional (i.e., “non-nano-enabled”) product, against which the MWCNT flame-retardant coating applied to upholstery textiles (i.e., the “nano-enabled” product) can be compared. The comparative element serves dual-purposes: 1) to provide a more robust database that facilitates identification of data gaps related to the nano-enabled product and 2) to provide a context for identifying key factors and data gaps for future efforts to evaluate risk-related trade-offs between a nano-enabled and non-nano-enabled product. This draft case study does not represent a completed or even a preliminary assessment of MWCNTs; rather, it uses the CEA framework to structure information from available literature and other resources (e.g., government reports) on the product life cycle, fate and transport processes in various environmental media, exposure-dose characterization, and impacts in human, ecological, and environmental receptors.