Biological Water Quality Criteria

EPA Pesticide Factsheets

Page contains links to Technical Documents pertaining to Biological Water Quality Criteria, including, technical assistance documents for states, tribes and territories, program overviews, and case studies.

Study design and hierarchy of evidence for surgical decision making.

PubMed

Sprague, Sheila; McKay, Paula; Thoma, Achilleas

2008-04-01

This article provides a historical overview of the hierarchy of evidence for surgical decision making and discusses key study designs in the hierarchy of evidence. This encompasses meta-analyses, randomized controlled trials, and observational studies, including cohort and case-controlled studies, case series and case reports, and basic science studies. This article also reviews the principles and importance of evidence-based plastic surgery and describes several systems to rate the strength of the scientific evidence.

Academic Integrity--A Review and Case Study.

ERIC Educational Resources Information Center

Dowd, Steven B.

Focusing on the role of the community college in promoting academic integrity, this paper provides a review of the literature and a case study describing the development of a relevant college-wide policy. First, a general overview of the role of colleges in promoting values is presented. Next, the literature review on cheating and plagiarism in…

Researching Language Teacher Cognition and Practice: International Case Studies

ERIC Educational Resources Information Center

Barnard, Roger, Ed.; Burns, Anne, Ed.

2012-01-01

This book presents a novel approach to discussing how to research language teacher cognition and practice. An introductory chapter by the editors and an overview of the research field by Simon Borg precede eight case studies written by new researchers, each of which focuses on one approach to collecting data. These approaches range from…

Inclusive Education in an International School: A Case Study from Hong Kong

ERIC Educational Resources Information Center

Chan, Twiggy; Yuen, Mantak

2015-01-01

This case study provides an overview of current policy, practices and problems concerning inclusion in one international secondary school in Hong Kong. A total of 13 interviews were conducted with the school management team, teachers, students and parents, supplemented by 12 classroom observations and two "student-shadowing" exercises.…

Office of exploration overview

NASA Technical Reports Server (NTRS)

Alred, John

1989-01-01

The NASA Office of Exploration case studies for FY89 are reviewed with regard to study ground rules and constraints. Three study scenarios are presented: lunar evolution, Mars evolution, and Mars expedition with emphasis on the key mission objectives.

Teaching Case: Security Breach at Target

ERIC Educational Resources Information Center

Plachkinova, Miloslava; Maurer, Chris

2018-01-01

This case study follows the security breach that affected Target at the end of 2013 and resulted in the loss of financial data for over 70 million customers. The case provides an overview of the company and describes the reasons that led to one of the biggest security breaches in history. It offers a discussion on Target's vendor management…

Managing Criticism in Ph.D. Supervision: A Qualitative Case Study

ERIC Educational Resources Information Center

Li, Sarah; Seale, Clive

2007-01-01

This article is part of a larger study which presents findings from an in-depth longitudinal case study of a student's Ph.D. journey. It shows how criticism is produced and managed in the supervisory relationship. As well as an overview of types of criticism produced across a range of supervisory interactions, the article presents a micro-analysis…

Nutrition and Its Effects on the Hyperkinetic Child's Behavior and Learning: A Case Study.

ERIC Educational Resources Information Center

Noonan, Roberta L.

This case study reviews the literature related to diet, behavior and learning and describes procedures and results of a change in the diet of an adolescent girl who had an extensive history of problems at home and at school. Studies of nutritional deficiency, nutritional imbalance, allergies, and synthetic food additives are briefly overviewed.…

Current Trends in Microform Use by Secondary Schools: Four Case Studies.

ERIC Educational Resources Information Center

Lee, Thomas Graham

The case study section of this booklet discusses a number of current microform programs in secondary schools. The remainder of the booklet presents an overview of microform activity, including comments on the history of secondary school microform utilization and an up-to-date listing of microform selection aids. The amount of information available…

Unemployment, Education, and Training: Case Studies from North America and Europe.

ERIC Educational Resources Information Center

Forrester, Keith, Ed.; Ward, Kevin, Ed.

This book contains 12 chapters, each of which is a case study or a commentary on the unemployment of the 1980s and early 1990s and on the programs devised to retrain workers. Titles and authors are as follows: "Understanding Unemployment: A Critical Overview of Labour Market Trends, Employment, and Unemployment: (John Hughes); "A…

Ka Lama o ke Kaiaulu: Research on Teacher Education for a Hawaiian Community.

ERIC Educational Resources Information Center

Au, Kathryn H.; Maaka, Margaret J.

1998-01-01

Introduces a three-year research project designed to answer the questions of how schools can better meet the educational needs of individuals from underrepresented groups. Provides overviews of a case study of a preservice teacher of Hawaiian ethnicity and a set of case studies of five Hawaiian women throughout their educations. (SLD)

Who "owns" the network: a case study of new media artists' use of high-bandwidth networks

NASA Astrophysics Data System (ADS)

Lesage, F.

The objective of this paper is to briefly give an overview of a research project dealing with the social construction of use of information communication technologies among new media artists interested in online collaboration. It will outline the theoretical and methodological tools applied to the case study of the MARCEL Network.

EMS Response to Mass Casualty Incidents: The Critical Importance of Automatic Statewide Mutual Aid and MCI Training

DTIC Science & Technology

2008-09-01

difficulty in implementation for each case study. After an overview, each case study is given a score against each of the criteria of “meets” or “exceeds...While expectations may be different for different individuals, the narrative section provides supporting information for the assigned score , with...decrease in response time will improve patient outcome? The narrative discussing the score will give information from the case study on the specific

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Fact sheet that provides a brief overview of the viability of LED street lighting in municipalities and highlights case studies of two cities—Los Angeles and Seattle—that have invested in LED street lighting.

Methods to control for unmeasured confounding in pharmacoepidemiology: an overview.

PubMed

Uddin, Md Jamal; Groenwold, Rolf H H; Ali, Mohammed Sanni; de Boer, Anthonius; Roes, Kit C B; Chowdhury, Muhammad A B; Klungel, Olaf H

2016-06-01

Background Unmeasured confounding is one of the principal problems in pharmacoepidemiologic studies. Several methods have been proposed to detect or control for unmeasured confounding either at the study design phase or the data analysis phase. Aim of the Review To provide an overview of commonly used methods to detect or control for unmeasured confounding and to provide recommendations for proper application in pharmacoepidemiology. Methods/Results Methods to control for unmeasured confounding in the design phase of a study are case only designs (e.g., case-crossover, case-time control, self-controlled case series) and the prior event rate ratio adjustment method. Methods that can be applied in the data analysis phase include, negative control method, perturbation variable method, instrumental variable methods, sensitivity analysis, and ecological analysis. A separate group of methods are those in which additional information on confounders is collected from a substudy. The latter group includes external adjustment, propensity score calibration, two-stage sampling, and multiple imputation. Conclusion As the performance and application of the methods to handle unmeasured confounding may differ across studies and across databases, we stress the importance of using both statistical evidence and substantial clinical knowledge for interpretation of the study results.

Three Year Outcome of a Child with Beckwith-Wiedemann Syndrome.

ERIC Educational Resources Information Center

Phillips, Rebecca Barsh; Prudencio, Ma. Concepcion; Russo, Sheila Daly; Estillore, Alicia; Reyes-Lee, Martha

1998-01-01

Presents a diminutive overview of research and a case study of Beckwith-Wiedemann syndrome (BWS), a rare, genetically complex congenital disorder. Prenatal diagnosis of this case included omphalocele, hydonephrosis, and possible horseshoe kidney, detected by ultrasound. The characteristics of this disability and related problems are discussed.…

Compositional Specification of Software Architecture

NASA Technical Reports Server (NTRS)

Penix, John; Lau, Sonie (Technical Monitor)

1998-01-01

This paper describes our experience using parameterized algebraic specifications to model properties of software architectures. The goal is to model the decomposition of requirements independent of the style used to implement the architecture. We begin by providing an overview of the role of architecture specification in software development. We then describe how architecture specifications are build up from component and connector specifications and give an overview of insights gained from a case study used to validate the method.

The Economic Value of Remote Sensing of Earth Resources from Space: An ERTS Overview and the Value of Continuity of Service. Volume 1: Summary

NASA Technical Reports Server (NTRS)

Hazelrigg, G. A., Jr.; Heiss, K. P.

1974-01-01

An overview of the ERTS program is given to determine the magnitude of the benefits that can be reasonably expected to flow from an Earth Resources Survey (ERS) Program, and to assess the benefits foregone in the event of a one or two-year gap in ERS services. An independent evaluation of the benefits attributable to ERS-derived information in key application areas is presented. These include two case studies in agriculture-distribution, production and import/export, and one study in water management. The cost-effectiveness of satellites in an ERS system is studied by means of a land cover case study. The annual benefits achieveable from an ERS system are measured by the in-depth case studies to be in the range of $430 to $746 million. Benefits foregone in the event of a one-year gap in ERS service are estimated to be $147 to $220 million and $274 to $420 million for a two-year gap in ERS service.

A brief overview of channel monitoring in land management: Five case studies. Case study #1

Treesearch

Leslie Reid

1999-01-01

Yesterday we heard about some successful monitoring programs,but today I would like to share some findings from a study I did, which was basically a post-mortem of failed monitoring programs.There were about 30 projects,and I wanted to know why did they fail,and were there patterns of why they failed.The projects ranged from university studies,land management,and...

Database on veterinary clinical research in homeopathy.

PubMed

Clausen, Jürgen; Albrecht, Henning

2010-07-01

The aim of the present report is to provide an overview of the first database on clinical research in veterinary homeopathy. Detailed searches in the database 'Veterinary Clinical Research-Database in Homeopathy' (http://www.carstens-stiftung.de/clinresvet/index.php). The database contains about 200 entries of randomised clinical trials, non-randomised clinical trials, observational studies, drug provings, case reports and case series. Twenty-two clinical fields are covered and eight different groups of species are included. The database is free of charge and open to all interested veterinarians and researchers. The database enables researchers and veterinarians, sceptics and supporters to get a quick overview of the status of veterinary clinical research in homeopathy and alleviates the preparation of systematical reviews or may stimulate reproductions or even new studies. 2010 Elsevier Ltd. All rights reserved.

Transferring Learning to the Workplace. Seventeen Case Studies from the Real World of Training. In Action Series.

ERIC Educational Resources Information Center

Broad, Mary L., Ed.

Organized in three parts, this book contains an introductory chapter and 17 case studies selected to show transfer applications in a wide range of organizational settings. In part 1, two chapters review the rationale, context, and research relating to transfer: "Transfer Concepts and Research Overview" (Mary Broad); and "Success Factors in…

The Use of Facebook to Build a Community for Distance Learning Students: A Case Study from the Open University

ERIC Educational Resources Information Center

Callaghan, George; Fribbance, Ian

2016-01-01

Social media platforms such as Facebook are commonplace throughout society. However, within higher education institutions such networking environments are still in the developmental stage. This paper describes and discusses case study data from the Open University's Faculty of Social Science Facebook page. It starts by giving an overview of the…

Mining Data from Weibo to WeChat: A Comparative Case Study of MOOC Communities on Social Media in China

ERIC Educational Resources Information Center

Zhang, Ke

2015-01-01

This article starts with an overview on China's MOOC phenomenon and social media, and then reports a comparative, multiple case study on three selected MOOC communities that have emerged on social media in China. These representative MOOC communities included: (a) MOOC Academy, the largest MOOC community in China, (b) Zhejiang University of…

Telling Our Story: A Case Study of a Collaborative Departmental Blog at Syracuse University Libraries

ERIC Educational Resources Information Center

Rauh, Anne E.; McReynolds, Stephanie J. H.

2016-01-01

This case study will take readers through the planning and publication process of a collaborative departmental library blog at Syracuse University, which is a large private, non-profit research intensive university located in central New York State. It will provide an overview of the history of the project and the mission of the blog. It will…

Computer Chips and Paper Clips. Technology and Women's Employment. Volume II. Case Studies and Policy Perspectives.

ERIC Educational Resources Information Center

Hartmann, Heidi I., Ed.; And Others

This volume contains 12 papers commissioned by the Panel on Technology and Women's Employment. "Technology, Women, and Work: Policy Perspectives" (Eli Ginzberg) is an overview that provides a context for the volume. The four case studies in Part II describe the impact of information technology in the insurance industry, among bookkeepers, among…

Case studies for GSHP demonstration projects in the US

DOE PAGES

Liu, Xiaobing; Malhotra, Mini; Im, Piljae

2015-07-01

Under the American Recovery and Reinvestment Act , twenty-six ground source heat pump (GSHP) projects were competitively selected and carried out to demonstrate the benefits of GSHP systems and innovative technologies for cost reduction and/or performance improvement. This article gives an overview of the case studies for six of the systems. These case studies evaluated efficiencies, energy savings, and costs of the demonstrated systems. In addition, it was found that more energy savings could be achieved if controls of GSHP system are improved.

PolarWindsII_DAWN_DC8_1

Atmospheric Science Data Center

2018-04-18

... Layer Winds Surface Winds Upper Level Winds Wind Profiles LIDAR Calibration/Validation Order Data:  ... Model Barrier Flow Case Study DAWN Coherent Wind Profiling Flights DAWN Overview and Preliminary Flight Results ...

MOVES sensitivity analysis update : Transportation Research Board Summer Meeting 2012 : ADC-20 Air Quality Committee

DOT National Transportation Integrated Search

2012-01-01

OVERVIEW OF PRESENTATION : Evaluation Parameters : EPAs Sensitivity Analysis : Comparison to Baseline Case : MOVES Sensitivity Run Specification : MOVES Sensitivity Input Parameters : Results : Uses of Study

Connected Vehicle Infrastructure : Deployment and Funding Overview

DOT National Transportation Integrated Search

2018-01-01

This report reviews existing and proposed legislation relevant to connected vehicle infrastructure (CVI) implementation, identifies existing funding mechanisms for CVI implementation, reviews CVI pilot programs and case studies, and provides an overv...

Liability and Safety in Physical Education and Sport: A Practitioner's Guide to the Legal Aspects of Teaching and Coaching in Elementary and Secondary Schools.

ERIC Educational Resources Information Center

Hart, James E.; Ritson, Robert J.

This second edition contains updated information and new case studies, offering guidance for safer programs and management of risk while reinforcing sound educational practices. The book features overviews of legal concepts and presents examples of situations from the trenches. Case studies illustrate a variety of teacher, coach, and administrator…

Flexible public transportation services in Florida.

DOT National Transportation Integrated Search

2013-08-01

This synthesis research provides an overview of the current use of flexible transportation services in Florida through administration of a survey and subsequent identification and examination of case study locations. The research included a literatur...

Design and Facilitation of Problem-Based Learning in Graduate Teacher Education: An MA TESOL Case

ERIC Educational Resources Information Center

Caswell, Cynthia Ann

2016-01-01

This exploratory, evaluative case study introduces a new context for problem-based learning (PBL) involving an iterative, modular approach to curriculum-wide delivery of PBL in an MA TESOL program. The introduction to the curriculum context provides an overview of the design and delivery features particular to the situation. The delivery approach…

Applying Corpus-Based Findings to Form-Focused Instruction: The Case of Reported Speech

ERIC Educational Resources Information Center

Barbieri, Federica; Eckhardt, Suzanne E. B.

2007-01-01

Arguing that the introduction of corpus linguistics in teaching materials and the language classroom should be informed by theories and principles of SLA, this paper presents a case study illustrating how corpus-based findings on reported speech can be integrated into a form-focused model of instruction. After overviewing previous work which…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This brochure provides an overview of the challenges and successes of New York City, NY, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

Ethical issues in engineering models: an operations researcher's reflections.

PubMed

Kleijnen, J

2011-09-01

This article starts with an overview of the author's personal involvement--as an Operations Research consultant--in several engineering case-studies that may raise ethical questions; e.g., case-studies on nuclear waste, water management, sustainable ecology, military tactics, and animal welfare. All these case studies employ computer simulation models. In general, models are meant to solve practical problems, which may have ethical implications for the various stakeholders; namely, the modelers, the clients, and the public at large. The article further presents an overview of codes of ethics in a variety of disciples. It discusses the role of mathematical models, focusing on the validation of these models' assumptions. Documentation of these model assumptions needs special attention. Some ethical norms and values may be quantified through the model's multiple performance measures, which might be optimized. The uncertainty about the validity of the model leads to risk or uncertainty analysis and to a search for robust models. Ethical questions may be pressing in military models, including war games. However, computer games and the related experimental economics may also provide a special tool to study ethical issues. Finally, the article briefly discusses whistleblowing. Its many references to publications and websites enable further study of ethical issues in modeling.

A Case Study on the Status of Technical and Vocational Education in Thailand. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Shoolap, Charoon; Choomnoom, Siripan

This two-part report presents an overview of the vocational and technical education system in Thailand. The first part is a review of the current and likely future situations pertaining to vocational and technical education in that country. An analysis of economic conditions, human resource development, and the existing technical and vocational…

Does Homeland Security Constitute an Emerging Academic Discipline?

DTIC Science & Technology

2013-03-01

Postgraduate School NSA National Security Agency OED Oxford English Dictionary U.S. United States xiv THIS PAGE INTENTIONALLY LEFT BLANK xv...Curriculum Design: A Case Study in Neuroscience ,” The Journal of Undergraduate Neuroscience Education 10, no. 1 (2011): A71–A79. 37 physical reaction...article entitled, “A Conceptual Framework for Interdisciplinary Curriculum Design: A Case Study in Neuroscience :”140 Table 2. An Overview of

A review of atmospheric and land surface processes with emphasis on flood generation in the Southern Himalayan rivers.

PubMed

Dimri, A P; Thayyen, R J; Kibler, K; Stanton, A; Jain, S K; Tullos, D; Singh, V P

2016-06-15

Floods in the southern rim of the Indian Himalayas are a major cause of loss of life, property, crops, infrastructure, etc. They have long term socio-economic impacts on the habitat living along/across the Himalayas. In the recent decade extreme precipitation events have led to numerous flash floods in and around the Himalayan region. Sporadic case-based studies have tried to explain the mechanisms causing the floods. However, in some of the cases, the causative mechanisms have been elusive. Various types of flood events have been debated at different spatial and temporal scales. The present study provides an overview of mechanisms that lead to floods in and around the southern rim of the Indian Himalayas. Atmospheric processes, landuse interaction, and glacier-related outbreaks are considered in the overview. Copyright © 2016 Elsevier B.V. All rights reserved.

BacNet and Analog/Digital Interfaces of the Building Controls Virtual Testbed

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nouidui, Thierry Stephane; Wetter, Michael; Li, Zhengwei

2011-11-01

This paper gives an overview of recent developments in the Building Controls Virtual Test Bed (BCVTB), a framework for co-simulation and hardware-in-the-loop. First, a general overview of the BCVTB is presented. Second, we describe the BACnet interface, a link which has been implemented to couple BACnet devices to the BCVTB. We present a case study where the interface was used to couple a whole building simulation program to a building control system to assess in real-time the performance of a real building. Third, we present the ADInterfaceMCC, an analog/digital interface that allows a USB-based analog/digital converter to be linked tomore » the BCVTB. In a case study, we show how the link was used to couple the analog/digital converter to a building simulation model for local loop control.« less

[Personal genome research and neurological diseases: overview].

PubMed

Toda, Tatsushi

2013-03-01

Neurological diseases include those caused by a single defective gene,e.g., Huntington's disease, other polyglutamine diseases, and muscular dystrophies, and those that are mostly sporadic but rarely show Mendelian inheritance in some families, e.g., Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and epilepsy. The latter diseases are considered polygenic disorders. Both sporadic and Mendelian cases of these diseases are believed to share some common pathological mechanisms. Since the detection of causal genes for the Mendelian cases, studies have been initiated on disease pathology. SNPs and rare gene variants play important roles in common neurological diseases. From a technological perspective, next-generation sequencers have become widely available and have contributed to the advancement of research based on individual genome sequences (personal genome). This paper presents an overview, as well as a historical context, of the contribution of personal genome research to neurological disease studies.

Raising Roma Educational Participation and Achievement: Collaborative Relationships, Transformative Change, and a Social Europe

ERIC Educational Resources Information Center

Ryder, Andrew Richard

2015-01-01

The paper gives an overview of Roma, Gypsy and Traveller (RGT) educational exclusion in the European Union and seeks to provide insights into good practice through case studies focusing on Bulgaria and the UK. The paper makes a case for the promotion of collaborative relationships, where RGT communities are active partners in developing curricula…

Fostering a Child's Foundational Skills Leading to Self-Determination: A Case Study of a Refugee Family, a Head Start Agency, and Their Family-Professional Partnership

ERIC Educational Resources Information Center

Haines, Shana Jackson

2013-01-01

This qualitative case study investigated and described the views of both Head Start staff and a refugee family regarding adult fostering of foundational skills leading to self-determination in a young child at risk for disability as well as how these adults worked together in partnership. Chapter 1 provides an overview of this dissertation. It…

Overview of the 1988 GCE/CASE/WATOX Studies of biogeochemical cycles in the North Atlantic region

NASA Astrophysics Data System (ADS)

Pszenny, Alexander A. P.; Galloway, James N.; Artz, Richard S.; Boatman, Joseph F.

1990-06-01

The 1988 Global Change Expedition/Coordinated Air-Sea Experiment/Western Atlantic Ocean Experiment (GCE/CASE/WATOX) was a multifaceted research program designed to study atmospheric and oceanic processes affecting the biogeochemical cycles of carbon, nitrogen, sulfur, and trace metals in the North Atlantic Ocean region. Field work included (1) a 49-day research cruise aboard NOAA ship Mt. Mitchell (Global Change Expedition) from Norfolk, Virginia, to Bermuda, Iceland, the Azores, and Barbados, (2) eight flights of the NOAA King Air research aircraft, four off the Virginia Capes and four near Bermuda (CASE/WATOX), and (3) a research cruise aboard the yacht Fleurtie near Bermuda (WATOX). Objectives of GCE/CASE/WATOX were (1) to examine processes controlling the mesoscale distributions of productivity, chlorophyll, and phytoplankton growth rates in Atlantic surface waters, (2) to identify factors controlling the distribution of ozone in the North Atlantic marine boundary layer, and (3) to estimate the contributions of sources on surrounding continents to the biogeochemical cycles of sulfur, nitrogen, and trace metals over the North Atlantic region during the boreal summer season. The individual papers in this and the next two issues of Global Biogeochemical Cycles provide details on the results and analyses of the individual measurement efforts. This paper provides a brief overview of GCE/CASE/WATOX.

W-8 Acoustic Casing Treatment Test Overview

NASA Technical Reports Server (NTRS)

Bozak, Rick; Podboy, Gary; Dougherty, Robert

2017-01-01

During February 2017, aerodynamic and acoustic testing was performed on a scale-model high bypass ratio turbofan rotor, R4, in an internal flow component test facility. An overview of the testing completed is presented.

POLLUTION PREVENTION CAST STUDIES COMPENDIUM - 2ND EDITION

EPA Science Inventory

This compendium summarizes a compilation of case studies in the area of pollution prevention. he compendium is divided into 3 sections, featuring 3 of the Pollution Prevention Branch's key programs. An overview of each program is provided at the beginning of each section of the c...

UCLA Community College Bibliography: Nursing Education and Community Colleges

ERIC Educational Resources Information Center

Liu, Amy

2007-01-01

The references presented in this bibliography provide an overview of recent scholarship concerning associate degree nursing students, faculty, and pedagogy at community colleges. Included in this bibliography are studies that incorporate a variety of methodologies ranging from quasi-experimental, case study, and naturalistic inquiry to correlation…

Megastudies, crowdsourcing, and large datasets in psycholinguistics: An overview of recent developments.

PubMed

Keuleers, Emmanuel; Balota, David A

2015-01-01

This paper introduces and summarizes the special issue on megastudies, crowdsourcing, and large datasets in psycholinguistics. We provide a brief historical overview and show how the papers in this issue have extended the field by compiling new databases and making important theoretical contributions. In addition, we discuss several studies that use text corpora to build distributional semantic models to tackle various interesting problems in psycholinguistics. Finally, as is the case across the papers, we highlight some methodological issues that are brought forth via the analyses of such datasets.

Knoxville, Tennessee: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-10-01

This brochure provides an overview of the challenges and successes of Knoxville, TN, a 2008 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

Austin, Texas: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This brochure provides an overview of the challenges and successes of Austin, Texas, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

Denver, Colorado: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This brochure provides an overview of the challenges and successes of Denver, Colorado, a 2008 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

Executive Coaching Practices in the Adult Workplace

ERIC Educational Resources Information Center

Campone, Francine

2015-01-01

This chapter provides an overview of key principles and practices in executive coaching. Coaching is discussed as a reflective learning opportunity and offers the theoretical grounding, strategies, and case studies for each of four key elements of a coaching engagement.

Madison, Wisconsin: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-10-01

This brochure provides an overview of the challenges and successes of Madison, WI, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

MONITORING, ASSESSMENT, AND ENVIRONMENTAL POLICY

EPA Science Inventory

This overview chapter examines the roles that environmental monitoring and assessment can play in the development of environmental policy. It takes a case study approach, focusing on the key roles played by monitoring data in policy formulation in acid deposition, stratospheric...

Case Studies of Non-Formal Education by Distance and Open Learning.

ERIC Educational Resources Information Center

Siaciwena, Richard, Ed.

This document contains seven papers from a study of the role of distance learning approaches in enhancing the contribution of nonformal education to socioeconomic development in Africa. "Introduction" (Richard Siaciwena) presents an overview of the research project and defines key terms related to nonformal education. "Ghana: The…

A Comparison Study of Second-Order Screening Designs and Their Extension

DTIC Science & Technology

2013-12-01

H2 97 V. Nonlinear Screening Designs for Defense Testing: An Overview and Case Study 5.1 Introduction “Necessity is the Mother of Invention.” Plato is...involved concepts like design resolution, minimum aber- ration , power, the number of clear (non-confounded) effects, concepts like rotatability

Knowledge Management Analysis: A Case Study

ERIC Educational Resources Information Center

Mecha, Ezi I.; Desai, Mayur S.; Richards, Thomas C.

2009-01-01

It is imperative for businesses to manage knowledge and stay competitive in the marketplace. Knowledge management is critical and is a key to prevent organizations from duplicating their efforts with a subsequent improvement in their efficiency. This study focuses on overview of knowledge management, analyzes the current knowledge management in…

Bank Community Development Corporations.

ERIC Educational Resources Information Center

Illinois State Dept. of Commerce and Community Affairs, Springfield.

This handbook provides a brief overview of bank and bank holding company community development corporations (CDCs), the types of activities for which they can be used, the legal requirements in establishing such an entity, and how they are organized and operated. Case studies, including studies of the Shorebank Corporation of Chicago, the First…

An Analysis of Class II Supplies Requisitions in the Korean Army’s Organizational Supply

DTIC Science & Technology

2009-03-26

five methods for qualitative research : Case study , Ethnography , 45 Phenomenological study , Grounded theory , and...Approaches .. 42 Table 9 Five Qualitative Research Methods ..................................................................... 45 Table 10 Six...Content analysis. Table 9 provides a brief overview of the five methods . Table 9 Five Qualitative

Monitored Natural Attenuation Case Study Evaluations

EPA Science Inventory

Monitored natural attenuation (MNA) has been selected as a component of groundwater remedies at several sites with metals and/or radionuclide contamination. An overview of the site characterization effort and remedy performance will be provided for several sites where MNA was se...

ENVIRONMENTAL ECONOMICS FOR WATERSHED RESTORATION

EPA Science Inventory

This book overviews non-market valuation, input-output analysis, cost-benefit analysis, and presents case studies from the Mid Atlantic Highland region, with all but the bare minimum econometrics, statistics, and math excluded or relegated to an appendix. It is a non-market valu...

San Antonio, Texas: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-10-01

This brochure provides an overview of the challenges and successes of San Antonio, TX, a 2008 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

San Diego, California: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-10-01

This brochure provides an overview of the challenges and successes of San Diego, CA, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

Case studies of market research for three transportation communication products

DOT National Transportation Integrated Search

1994-03-01

This report completes a two-part project in support of the Volpe Center program, Public Acceptance and Markets for Various IVHS Services. The first report, A Primer on Marketing Research, provides an overview of the research approaches an...

Minneapolis and Saint Paul, Minnesota: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-10-01

This brochure provides an overview of the challenges and successes of Minneapolis, MN, a 2008 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

San Francisco, California: Solar in Action (Brochure)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-10-01

This brochure provides an overview of the challenges and successes of San Francisco, CA, a 2007 Solar America City awardee, on the path toward becoming a solar-powered community. Accomplishments, case studies, key lessons learned, and local resource information are given.

EIA model documentation: World oil refining logistics demand model,``WORLD`` reference manual. Version 1.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-04-11

This manual is intended primarily for use as a reference by analysts applying the WORLD model to regional studies. It also provides overview information on WORLD features of potential interest to managers and analysts. Broadly, the manual covers WORLD model features in progressively increasing detail. Section 2 provides an overview of the WORLD model, how it has evolved, what its design goals are, what it produces, and where it can be taken with further enhancements. Section 3 reviews model management covering data sources, managing over-optimization, calibration and seasonality, check-points for case construction and common errors. Section 4 describes in detailmore » the WORLD system, including: data and program systems in overview; details of mainframe and PC program control and files;model generation, size management, debugging and error analysis; use with different optimizers; and reporting and results analysis. Section 5 provides a detailed description of every WORLD model data table, covering model controls, case and technology data. Section 6 goes into the details of WORLD matrix structure. It provides an overview, describes how regional definitions are controlled and defines the naming conventions for-all model rows, columns, right-hand sides, and bounds. It also includes a discussion of the formulation of product blending and specifications in WORLD. Several Appendices supplement the main sections.« less

An overview of UK C130 observations from the FIRE marine stratocumulus IFO

NASA Technical Reports Server (NTRS)

Nicholls, S.; Leighton, J.; Barlow, R.

1990-01-01

An overview of the characteristics of the ten flights made by the C130 during the Intensive Field Observations (IFO) are presented. An indication of data quality is given. Comparisons of the carbon dioxide radiation thermometer and the Rosemount suggest there may be potentially serious wetting problems with the latter, especially close to cloud base. The main features of the cloud layers sampled by the C130 are summarized, including microphysical parameters. Many of the results shown are derived from a first order analysis of turbulence quantities. The gross vertical variation of heat, vapor, and liquid water fluxes from case to case, together with the observed vertical velocity variance, a good indicator of convective activity, are discussed. Preliminary results suggest that the different cases can be usefully categorized using these data. The relationship between these and the measured boundary conditions is mentioned. Similarities and differences between the various cases are highlighted, and interpreted in terms of the researchers' current understanding of stratocumulus. Attention is given to particular features of the various flights which may deserve more intensive study.

Cambridge Desegregation Succeeding.

ERIC Educational Resources Information Center

Alves, Michael

1983-01-01

This paper provides an overview of the controversy concerning "freedom of choice" desegregation plans and presents a case study of the plan adopted by Cambridge, Massachusetts, in 1981. Following the introduction, a short explanation of the plan's distinctive feature, controlled open enrollment, is given. (Under controlled open…

Factors leading to the involvement of Forensic Advisors in the Belgian criminal justice system.

PubMed

Bitzer, Sonja

2018-04-01

Forensic Advisors at the National Institute for Criminalistics and Criminology in Brussels act as advising body to the magistrate regarding analytical possibilities and the usefulness of trace analysis in a case. Initially, their function was devised to assist in complex murder cases with unknown offender. However, in a previous study, the increasing diversity of the cases they are requested for has been observed (Bitzer et al., in press). In order to deepen our understanding of the decision steps in the criminal investigation process, the decision to involve a Forensic Advisor and the factors leading to their involvement were evaluated. The study focused on homicide, robbery and burglary cases with and without requests for a Forensic Advisor between January 2014 and June 2016. The factors were categorised into five knowledge dimensions: strategic, immediate, physical, criminal and utility. Decision tree modelling was carried out in order to identify the factors influencing the request for a Forensic Advisor in the case. The decision to request a Forensic Advisor differs between different types of offences. It also depends on the complexity of the case in terms of the number of traces and objects collected at the crime scene, and the availability of witness reports. Indeed, Forensic Advisors take the role of trace analysis coordinator by providing an overview of all available traces, objects, analyses and results. According to the principal implication factors and the performed case study, the contribution of Forensic Advisors consists mainly in summarising all information and advise on potential additional analyses. This might be explained by a loss of overview of the information and the possibilities regarding trace analysis by the magistrate responsible of the case. Copyright © 2018 Elsevier B.V. All rights reserved.

Japanese Migration and the Americas: An Introduction to the Study of Migration.

ERIC Educational Resources Information Center

Mukai, Gary; Brunette, Rachel

This curriculum module introduces students to the study of migration, including a brief overview of some categories of migration and reasons why people migrate. As a case study, the module uses the Japanese migration experience in the United States, Peru, Brazil, Canada, Mexico, Argentina, Bolivia, and Paraguay. The module introduces students to…

Academic Marginalism in Western Balkans: The Case of Croatia

ERIC Educational Resources Information Center

Brajkovic, Lucia

2016-01-01

This qualitative study relies on document analysis and in-depth, open-ended interviews with university leaders and government officials in a post-socialist and a recent European Union entrant country, Croatia. The study seeks to provide a comprehensive overview of the Croatian academic sector, as well as to unpack the top academic officials'…

Understanding Australian Aboriginal Tertiary Student Needs

ERIC Educational Resources Information Center

Oliver, Rhonda; Rochecouste, Judith; Bennell, Debra; Anderson, Roz; Cooper, Inala; Forrest, Simon; Exell, Mike

2013-01-01

Drawing from a study of the experiences of Australian Aboriginal and Torres Strait Islander university students, this paper presents an overview of the specific needs of these students as they enter and progress through their tertiary education. Extracts from a set of case studies developed from both staff and student interviews and an online…

First Love: A Case Study in Quantitative Appropriation of Social Concepts

ERIC Educational Resources Information Center

Janssen, Diederik F.

2008-01-01

Peer love is a highly invested autobiographical marker, and its scientific ascent can be studied in terms of its literature's motives, stated objectives, exclusions, and delimitations. In this article an overview of numeric and selected ethnographic data on the timing of "first love" is presented, to inform an assessment of the ontological…

Compilation of Case Studies: Exemplary Placement and Follow-Up Studies.

ERIC Educational Resources Information Center

Dale, Jack

Examples of placement and follow-up conceptual models developed for a program of vocational education (kindergarten through university) are presented. Section 1 contains a historical overview of placement and follow-up activities in Florida and describes a comprehensive model. Section 2, describing a model for utilizing community resources for the…

Single-Case Design Research: Building the Evidence-Base in the Field of Education of Deaf and Hard of Hearing Students

ERIC Educational Resources Information Center

Cannon, Joanna E.; Guardino, Caroline; Antia, Shirin D.; Luckner, John L.

2015-01-01

The field of education of deaf and hard of hearing (DHH) students has a paucity of evidence-based practices (EBPs) to guide instruction. The authors discussed how the research methodology of single-case design (SCD) can be used to build EBPs through direct and systematic replication of studies. An overview of SCD research methods is presented,…

Modeling zero-modified count and semicontinuous data in health services research part 2: case studies.

PubMed

Neelon, Brian; O'Malley, A James; Smith, Valerie A

2016-11-30

This article is the second installment of a two-part tutorial on the analysis of zero-modified count and semicontinuous data. Part 1, which appears as a companion piece in this issue of Statistics in Medicine, provides a general background and overview of the topic, with particular emphasis on applications to health services research. Here, we present three case studies highlighting various approaches for the analysis of zero-modified data. The first case study describes methods for analyzing zero-inflated longitudinal count data. Case study 2 considers the use of hurdle models for the analysis of spatiotemporal count data. The third case study discusses an application of marginalized two-part models to the analysis of semicontinuous health expenditure data. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

How to Study the Influence of Intensity of Treatment on Generalized Skill and Knowledge Acquisition in Students with Disabilities

ERIC Educational Resources Information Center

Yoder, Paul J.; Woynaroski, Tiffany

2015-01-01

Seven empirical studies from this special issue and an overview chapter are reviewed to illustrate several points about studying the possible effects of treatment intensity manipulations on generalized skill or knowledge acquisition in students with disabilities. First, we make a case in favor of studying intensity as separate from complexity and…

Crime and Justice: 10 Activities.

ERIC Educational Resources Information Center

Constitutional Rights Foundation, Los Angeles, CA.

This manual contains learning activities to aid secondary teachers in clarifying and enriching the Scholastic materials "Living Law." The format of the manual includes a brief overview, background information, teacher instructions, and a description of each activity. Case studies, simulations, and role-playing activities are provided. Topics…

Challenges in Recruiting Aging Women Holocaust Survivors to a Case Control Study of Breast Cancer.

PubMed

Vin-Raviv, Neomi; Dekel, Rachel; Barchana, Micha; Linn, Shai; Keinan-Boker, Lital

2015-01-01

Older adults are underrepresented in medical research for many reasons, including recruitment difficulties. Recruitment of older adults for research studies is often a time-consuming process and can be more challenging when the study involves older adults with unique exposures to traumatic events and from minority groups. The current article provides a brief overview of (a) challenges encountered while recruiting aging women Holocaust survivors for a case control study and (b) strategies used for meeting those challenges. The case group comprised women Holocaust survivors who were recently diagnosed with breast cancer and the control group comprised healthy women from a Holocaust-survivor community in Israel. Copyright 2015, SLACK Incorporated.

New psychoactive substances: an overview on recent publications on their toxicodynamics and toxicokinetics.

PubMed

Meyer, Markus R

2016-10-01

This review article covers English-written and PubMed-listed review articles and original studies published between January 2015 and April 2016 dealing with the toxicodynamics and toxicokinetics of new psychoactive substances. Compounds covered include stimulants and entactogens, synthetic cannabinoids, tryptamines, NBOMes, phencyclidine-like drugs, benzodiazepines, and opioids. First, an overview and discussion is provided on timely review articles followed by an overview and discussion on recent original studies. Both sections are then concluded by an opinion on these latest developments. This review shows that the NPS market is still highly dynamic and that the data published on their toxicodynamics and toxicokinetics can hardly keep pace with the appearance of new entities. However, data available are very helpful to understand and predict how NPS may behave in severe intoxication. The currently best-documented parameter is the in vitro metabolism of NPS, a prerequisite to allow detection of NPS in biological matrices in cases of acute intoxications or chronic consumption. However, additional data such as their chronic toxicity are still lacking.

Commercial Buildings Partnerships - Overview of Higher education projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parrish, Kristen; Robinson, Alastair; Regnier, Cindy

2013-02-01

The Commercial Building Partnership (CBP), a public/private, cost-shared program sponsored by the U.S. Department of Energy (DOE), paired selected commercial building owners and operators with representatives of DOE, its national laboratories, and private-sector technical experts. These teams explored energy-saving measures across building systems – including some considered too costly or technologically challenging – and used advanced energy modeling to achieve peak whole-building performance. Modeling results were then included in new construction or retrofit designs to achieve significant energy reductions. CBP design goals aimed to achieve 50 percent energy savings compared to ANSI/ASHRAE/IES Standard 90.1-2004 for new construction, while retrofits aremore » designed to consume at least 30 percent less energy than either Standard 90.1-2004 or current consumption. After construction and commissioning of the project, laboratory staff continued to work with partners to collect and analyze data for verification of the actual energy reduction. CBP projects represent diverse building types in commercial real estate, including lodging, grocery, retail, higher education, office, and warehouse/storage facilities. Partners also commit to replicating low-energy technologies and strategies from their CBP projects throughout their building portfolios. As a result of CBP projects, five sector overviews (Lodging, Food Sales, General Merchandise, Higher Education, Offices) were created to capture successful strategies and recommended energy efficiency measures that could broadly be applied across these sectors. These overviews are supplemented with individual case studies providing specific details on the decision criteria, modeling results, and lessons learned on specific projects. Sector overviews and CBP case studies will also be updated to reflect verified data and replication strategies as they become available.« less

[Indication, type of resection and results of surgery in cases of lung tuberculosis. A historical and regional overview].

PubMed

Hillejan, L; Nemat, A; Marra, A; Stamatis, G

2002-06-01

Pulmonary tuberculosis has become a rare indication for surgical intervention in all industrial nations. Over a period of 10 years we overview 193 patients who were suffering this disease and underwent thoracotomy. Main indication (79.8 %) was pulmonary nodules, of unknown origin. In this cases wedge resection was performed. Expanded resectional techniques were necessary in cases of cavernes, superinfected bronchiectasis, bronchial stenosis, hemoptysis and destroyed lungs due to tuberculosis. Considering the heterogenous groups of patients, the perioperative morbidity (21.8 %) and mortality (0.5 %) has to be regarded in comparison to the data found in the literature.

77 FR 33195 - Western Pacific Fishery Management Council; Public Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... Workshop A. Introduction and Overview of FAD Issues in the Western Pacific Region B. Case Study of Local... Management Council; Public Meetings AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice of public meetings and hearings. SUMMARY: The...

Parent Involvement Facilitators: Unlocking Social Capital Wealth

ERIC Educational Resources Information Center

Ferrara, Margaret M.

2015-01-01

This case study provides an overview of a family outreach intervention that supports student retention in school through a school-home communication link. This intervention structure, which employs staff appropriately called parent involvement facilitators (PIFs), is one that school districts have employed to facilitate family engagement in…

Action Learning in China

ERIC Educational Resources Information Center

Marquardt, Michael J.

2015-01-01

Action learning was introduced into China less than 20 years ago, but has rapidly become a valuable tool for organizations seeking to solve problems, develop their leaders, and become learning organizations. This article provides an historical overview of action learning in China, its cultural underpinnings, and five case studies. It concludes…

A Case Study in E-Journal Developments: The Scandinavian Position.

ERIC Educational Resources Information Center

Joa, Harald

1997-01-01

Provides an overview of peer-reviewed scientific and scholarly electronic journals in Scandinavia from a publisher's point of view. Discusses the electronic journals market in Scandinavia, international electronic publishing, the Institute for Scientific Information's Electronic Library Project, the one-stop shopping concept, and copyright and…

The Labor Market Impacts of the Private Retirement System. Studies in Public Welfare, Paper No. 11.

ERIC Educational Resources Information Center

Taggart, Robert

After giving an overview of the private retirement system and considering deferred wages and labor costs, the study explores the extent of the influence of private pensions on early retirement and on job opportunities of older persons, and the influence of lengthy job tenure requirements on worker mobility. The study weakens the case for…

Computer aided system engineering and analysis (CASE/A) modeling package for ECLS systems - An overview

NASA Technical Reports Server (NTRS)

Dalee, Robert C.; Bacskay, Allen S.; Knox, James C.

1990-01-01

An overview of the CASE/A-ECLSS series modeling package is presented. CASE/A is an analytical tool that has supplied engineering productivity accomplishments during ECLSS design activities. A components verification program was performed to assure component modeling validity based on test data from the Phase II comparative test program completed at the Marshall Space Flight Center. An integrated plotting feature has been added to the program which allows the operator to analyze on-screen data trends or get hard copy plots from within the CASE/A operating environment. New command features in the areas of schematic, output, and model management, and component data editing have been incorporated to enhance the engineer's productivity during a modeling program.

Building America Energy Renovations. A Business Case for Home Performance Contracting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baechler, Michael C.; Antonopoulos, C. A.; Sevigny, M.

2012-10-01

This research report gives an overview of the needs and opportunities that exist in the U.S. home performance contracting industry. The report discusses industry trends, market drivers, different business models, and points of entry for existing and new businesses hoping to enter the home performance contracting industry. Case studies of eight companies who successfully entered the industry are provided, including business metrics, start-up costs, and marketing approaches.

Enhancing work outcome for three persons with traumatic brain injury.

PubMed

Target, P; Wehman, P; Petersen, R; Gorton, S

1998-03-01

A case study approach is used to illustrate how three survivors of severe traumatic brain injury were able to gain and maintain employment with the assistance of a supported employment programme. Emphasis on the different types of accommodations, including the design and implementation of compensatory strategies, is provided for each case. Finally, on overview of steps that can be taken to enhance the use of such strategies on the job is presented.

A Study of New Mexico Migrant Agricultural Workers.

ERIC Educational Resources Information Center

Borrego, John G.; And Others

The intent of this report, as stated, is to bring about an awareness of the kinds of problems faced by migrant agricultural workers (Mexican Americans and Navajos), by farmers, and by agencies offering services to these migrants in New Mexico. An overview of the national and state migrant situation is presented, as well as case studies of various…

Designing and Implementing ESP Courses in French Higher Education: A Case Study

ERIC Educational Resources Information Center

Birch-Bécaas, Susan; Hoskins, Laüra

2017-01-01

This chapter reports on the design, implementation and evaluation of an English for Specific Purposes (ESP) course for dental students at the University of Bordeaux. We give an overview of the "English for Dental Studies" courses taught from second year through to fifth year before focussing on the fifth year course in which the…

Study of New Youth Initiatives in Apprenticeship. Interim Report. Volume 2: Site Visit Reports.

ERIC Educational Resources Information Center

CSR, Inc., Washington, DC.

This second volume of the interim report provides detailed case study reports on each of the eight Youth Apprenticeship Projects. (Volume 1, an overview of data from the site visits, is available separately as CE 032 791.) Discussion areas covered in each site visit report are local context/operational environment, administrative information,…

Knowledge Discovery Process: Case Study of RNAV Adherence of Radar Track Data

NASA Technical Reports Server (NTRS)

Matthews, Bryan

2018-01-01

This talk is an introduction to the knowledge discovery process, beginning with: identifying the problem, choosing data sources, matching the appropriate machine learning tools, and reviewing the results. The overview will be given in the context of an ongoing study that is assessing RNAV adherence of commercial aircraft in the national airspace.

Professional Online Presence and Learning Networks: Educating for Ethical Use of Social Media

ERIC Educational Resources Information Center

Forbes, Dianne

2017-01-01

In a teacher education context, this study considers the use of social media for building a professional online presence and learning network. This article provides an overview of uses of social media in teacher education, presents a case study of key processes in relation to professional online presence and learning networks, and highlights…

Line transect estimation of population size: the exponential case with grouped data

USGS Publications Warehouse

Anderson, D.R.; Burnham, K.P.; Crain, B.R.

1979-01-01

Gates, Marshall, and Olson (1968) investigated the line transect method of estimating grouse population densities in the case where sighting probabilities are exponential. This work is followed by a simulation study in Gates (1969). A general overview of line transect analysis is presented by Burnham and Anderson (1976). These articles all deal with the ungrouped data case. In the present article, an analysis of line transect data is formulated under the Gates framework of exponential sighting probabilities and in the context of grouped data.

Making a Case for a Cross-Cultural Approach to Literacy in Appalachia.

ERIC Educational Resources Information Center

Thaller, Eva A.

An insider/outsider approach to Appalachian culture examines cultural differences of Appalachian people that necessitate cross-cultural educational studies usually reserved for ethnic and racial minority groups. An overview focuses on current economic conditions affecting the region's culture and some stereotypes of Appalachians that remain…

Overview of EPA tools for supporting local- and regional-scale decision makers addressing energy and environmental issues

EPA Science Inventory

EPA’s Office of Research and Development (ORD) has been developing tools and illustrative case studies for decision makers in local and regional authorities who are facing challenges of establishing resilience to extreme weather events, aging built environment and infrastru...

Beyond the Language Classroom

ERIC Educational Resources Information Center

Benson, Phil, Ed.; Reinders, Hayo, Ed.

2011-01-01

This comprehensive exploration of theoretical and practical aspects of out-of-class teaching and learning, from a variety of perspectives and in various settings around the world, includes a theoretical overview of the field, 11 data-based case studies, and practical advice on materials development for independent learning. Contents of this book…

A Service-Learning Model for At-Risk Adolescents

ERIC Educational Resources Information Center

Nelson, Judith A.; Eckstein, Daniel

2008-01-01

This article describes a service-learning case study and program description involving the development and the delivery of services in a Disciplinary Alternative Education Program for secondary students. Following an overview of the philosophy of constructivist theory applied to the concept of the dissemination of information concerning adolescent…

Exploring the Benefits of Teacher-Modeling Strategies Integrated into Career and Technical Education

ERIC Educational Resources Information Center

Cathers, Thomas J., Sr.

2013-01-01

This case study examined how career and technical education classes function using multiple instructional modeling strategies integrated into vocational and technical training environments. Seven New Jersey public school technical teachers received an introductory overview of the investigation and participated by responding to 10 open-end…

Geostatistics and petroleum geology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hohn, M.E.

1988-01-01

This book examines purpose and use of geostatistics in exploration and development of oil and gas with an emphasis on appropriate and pertinent case studies. It present an overview of geostatistics. Topics covered include: The semivariogram; Linear estimation; Multivariate geostatistics; Nonlinear estimation; From indicator variables to nonparametric estimation; and More detail, less certainty; conditional simulation.

Disruptive Innovation in Air Measurement Technology: Reality or Hype?

EPA Science Inventory

This presentation is a big picture overview on the changing state of air measurement technology in the world, with a focus on the introduction of low-cost sensors into the market place. The presentation discusses how these new technologies may be a case study in disruptive innov...

The Evolving Virtual Library: Visions and Case Studies.

ERIC Educational Resources Information Center

Saunders, Laverna M., Ed.

This book addresses many of the practical issues involved in developing the virtual library. Seven presentations from the Eighth Annual Computers in Libraries Conference are included in this book in augmented form. The papers are supplemented by "The Evolving Virtual Library: An Overview" (Laverna M. Saunders and Maurice Mitchell), a…

Communicating in the '80s. New Options for the Nonprofit Community.

ERIC Educational Resources Information Center

Green, Alan

This booklet includes descriptions of new communications technologies and case studies of how they can be used in planning for appropriate and effective use of technology to enhance service to the public. Single-page overviews of satellites, broadcasting, videotex, cable television, microcomputers, teleconferencing, personal video, and telephones…

A Special Issue: Geomathematics in practice: Case studies from earth- and environmental sciences - Proceedings of the Croatian-Hungarian Geomathematical Congress, Hungary 2015

NASA Astrophysics Data System (ADS)

Hatvani, István Gábor; Horváth, Janina

2016-01-01

The present paper aims to introduce the current problems of geomathematics along with giving on overview on the papers published in the special issue covering the Croatian-Hungarian Geomathematical Congress of 2015 in Hungary.

Using Satellite Data to Monitor the Impacts of CyanoHAB Events on Drinking Water: A Texas Case Study

EPA Science Inventory

Overview of CYAN and it's mission to support the environmental management and public use of U.S. lakes and estuaries by providing a capability of detecting and quantifying algal blooms and related water quality using satellite data records.

Integrating Shamanic Methodology into the Spirituality of Addictions Recovery Work

ERIC Educational Resources Information Center

Rich, Marcia L.

2012-01-01

Responding to an increased recognition of the importance of spirituality in the aetiology and treatment of addictions, this article provides an overview of the potential contributions of both transpersonal psychology and shamanic methodology for the addictions field. A case study is provided to illustrate the integration of conventional,…

Senecavirus A: overview of experimental studies

USDA-ARS?s Scientific Manuscript database

Introduction Senecavirus A (SVA) is a picornavirus in the same family as Foot and Mouth Disease virus (FMDV) and swine vesicular disease virus (SVDV). SVA has been associated with rare cases of idiopathic vesicular disease (IVD) in the past. A "mini-epidemic" of IVD in US finisher and sow farms beg...

International Handbook of Educational Reform.

ERIC Educational Resources Information Center

Cookson, Peter W., Jr., Ed.; And Others

This book provides an overview of education reform in 27 countries. Following the introduction by Peter W. Cookson, Jr., Alan R. Sadovnik, and Susan F. Semel, part 1 offers national case studies of educational reform in the 1980s. Chapters include: (2) "Argentina" (Ana Munoz-Sandoval); (3) "Australia" (Richard Teese); (4) "Brazil" (Robert Cowen…

The Infertility Experience: Biopsychosocial Effects and Suggestions for Counselors

ERIC Educational Resources Information Center

Watkins, Kathryn J.; Baldo, Tracy D.

2004-01-01

Infertility affects many individuals and couples. This article begins with a case study of a couple who have experienced infertility yet do not identify infertility as their presenting problem. Clients and counselors alike often overlook infertility. This article offers an overview of the biology of infertility and its psychological and…

ACHP | Energy Development, Transmission, and Historic Preservation

Science.gov Websites

provided an overview of select Section 106 cases in which the ACHP was involved. The cases below are this link to find 106 cases involving energy. Photovoltaic System on Roof of Ballaja Building, Spring

Hydraulic Fracturing of Soils; A Literature Review.

DTIC Science & Technology

1977-03-01

best case, or worst case. The study reported herein is an overview of one such test or technique, hydraulic fracturing , which is defined as the...formation of cracks, in soil by the application of hydraulic pressure greater than the minor principal stress at that point. Hydraulic fracturing , as a... hydraulic fracturing as a means for determination of lateral stresses, the technique can still be used for determining in situ total stress and permeability at a point in a cohesive soil.

Overview: The Design, Adoption, and Analysis of a Visual Document Mining Tool for Investigative Journalists.

PubMed

Brehmer, Matthew; Ingram, Stephen; Stray, Jonathan; Munzner, Tamara

2014-12-01

For an investigative journalist, a large collection of documents obtained from a Freedom of Information Act request or a leak is both a blessing and a curse: such material may contain multiple newsworthy stories, but it can be difficult and time consuming to find relevant documents. Standard text search is useful, but even if the search target is known it may not be possible to formulate an effective query. In addition, summarization is an important non-search task. We present Overview, an application for the systematic analysis of large document collections based on document clustering, visualization, and tagging. This work contributes to the small set of design studies which evaluate a visualization system "in the wild", and we report on six case studies where Overview was voluntarily used by self-initiated journalists to produce published stories. We find that the frequently-used language of "exploring" a document collection is both too vague and too narrow to capture how journalists actually used our application. Our iterative process, including multiple rounds of deployment and observations of real world usage, led to a much more specific characterization of tasks. We analyze and justify the visual encoding and interaction techniques used in Overview's design with respect to our final task abstractions, and propose generalizable lessons for visualization design methodology.

Cases and Controversy: Guide to Teaching the Public Issues Series/Harvard Social Studies Project, and Supplement.

ERIC Educational Resources Information Center

Oliver, Donald W.; Newmann, Fred M.

This general guide presents an overview and explains the rationale of the teaching approach of the "Public Issues Series," units produced by the Harvard Social Studies Project to help students in grades 9-19 analyze and discuss human dilemmas related to public issues. (A detailed report on the nature, development, and evaluation of the Harvard…

Attitudes to Ancient Greek in Three Schools: A Case Study

ERIC Educational Resources Information Center

Foster, Frances

2018-01-01

This study comes in response to recent changes in UK policy, whereby Ancient Greek and Latin have been included alongside modern languages as part of the curriculum at Key Stage 2. It aims to understand how Ancient Greek is surviving and thriving in three different types of schools. After a short overview of the history of Greek teaching in the…

Investigation of DBMS for Use in a Research Environment. Rand Paper Series 7002.

ERIC Educational Resources Information Center

Rosenfeld, Pilar N.

This investigation of the use of database management systems (DBMS) in a research environment used the Rand Corporation as a case study. After a general introduction in section 1, eight sections present the major components of the study. Section 2 contains an overview of DBMS terminology and concepts, followed in section 3 by a general dsecription…

Exploring the Transformative Potential of Recognition of Prior Informal Learning for Learners: A Case Study in Scotland

ERIC Educational Resources Information Center

Brown, Julie

2017-01-01

This article presents an overview of the findings of a recently completed study exploring the potentially transformative impact upon learners of recognition of prior informal learning (RPL). The specific transformative dimension being reported is learner identity. In addition to providing a starting point for an evidence base within Scotland, the…

SMART NAS Test Bed Overview

NASA Technical Reports Server (NTRS)

Palopo, Kee

2016-01-01

These slides presents an overview of SMART NAS Test Bed. The test bed is envisioned to be connected to operational systems and to allow a new concept and technology to be evaluated in its realistic environment. Its role as an accelerator of concepts and technologies development, its use-case-driven development approach, and its state are presented.

Nurse's Breakout Session Injury/Illness Case Management

NASA Technical Reports Server (NTRS)

Hesselgesser, Connie

2001-01-01

An overview of the work related injury and illness case management model developed at the Johnson Space Center was presented. The major accomplishments and the challenges of implementation were discussed.

Teaching Business Communication on the Production Line: A Case Study.

ERIC Educational Resources Information Center

Moore, Richard W.

1993-01-01

Analyzes the communication training received by over 4,000 workers as part of an effort to implement a team concept production system at a General Motors plant. Presents an overview of the team concept training. Discusses five barriers to effective training, four successful instructional methods, and implications for business communication. (RS)

EPA Workshop on Monitored Natural Attenuation for Inorganic Contaminants: 3 – Discussion of Specific Contaminants & Case Study

EPA Science Inventory

The purpose of this training is to present an overview of site characterization approaches to support evaluation of the potential for Monitored Natural Attenuation (MNA) as a remedy for inorganic contaminants in ground water. The training will include discussion of the types of ...

Internet Addiction: College Student Case Study Using Best Practices in Cognitive Behavior Therapy.

ERIC Educational Resources Information Center

Hall, Alex S.; Parsons, Jeffrey

2001-01-01

Internet Behavior Dependence (IBD), a form of Internet addiction, is a new disorder requiring informed response from addictions clinicians such as mental health counselors. Presents a working definition for IBD, overviews the prevalence rates and demographic profiles of dependent users, and reviews assessment criteria and treatment for IBD.…

Teaching History with Museums: Strategies for K-12 Social Studies

ERIC Educational Resources Information Center

Marcus, Alan; Stoddard, Jeremy; Woodward, Walter W.

2011-01-01

"Teaching History with Museums" provides an introduction and overview of the rich pedagogical power of museums. In this comprehensive textbook, the authors show how museums offer a sophisticated understanding of the past and develop habits of mind in ways that are not easily duplicated in the classroom. Using engaging cases to illustrate…

A Model for Outsourcing HRD

ERIC Educational Resources Information Center

Simmonds, David; Gibson, Rebecca

2008-01-01

Purpose: The purpose of this paper is to provide an overview of approaches to outsourcing HRD in the UK. Design/methodology/approach: This paper employs semi-structured interviews and case studies. The research model was developed from a literature review. Findings: There are many problems associated with outsourcing any or all aspects of the HRD…

Racial Identity Development and Academic Achievement of Academically Gifted African American Students: Implications for School Counselors

ERIC Educational Resources Information Center

Spencer, Natalie F.; Dowden, Angel Riddick

2014-01-01

Gifted African American students are underrepresented and underserved in gifted education. The current article provides an overview of proper identification, racial identity development implications, psycho-social concerns and the importance of family involvement in the development of gifted African American students. A case study is presented to…

Child Sexual Abuse: Prevention and Treatment. Continuing Education Manual.

ERIC Educational Resources Information Center

Stovall, Bennie

This self-study manual, for use by individuals or groups, was developed for social work practitioners, and focuses on total family assessment to determine prevention and treatment intervention in cases of child sexual abuse and neglect. The introduction presents the philosophy of continuing education on which the manual is based, an overview of…

Outplacement and Re-Employment Measures during Organizational Restructuring in Belgium: Overview of the Literature and Results of Qualitative Research

ERIC Educational Resources Information Center

De Witte, Hans; Vandoorne, Jan; Verlinden, Roel; De Cuyper, Nele

2005-01-01

Purpose: Aims to review the research literature and legislation on outplacement and re-employment interventions in Belgium and present results of qualitative research and case studies of companies, regarding interventions during organizational restructuring. Design/methodology/approach: Comprises a literature review, qualitative (semi-structured…

Contracting for Facilities Services. Critical Issues in Facilities Management. No. 9.

ERIC Educational Resources Information Center

APPA: Association of Higher Education Facilities Officers, Alexandria, VA.

This book has been designed to provide practical information to managers on how to work with outside contractors in the higher education facilities area, and provides "real world" advice on the opportunities and pitfalls of privatization. Overviews and detailed case studies of contracting-out for services such as custodial services and…

An Integrated Decision-Making Framework for Sustainability Assessment: A Case Study of Memorial University

ERIC Educational Resources Information Center

Waheed, Bushra; Khan, Faisal; Veitch, Brian; Hawboldt, Kelly

2011-01-01

This article presents an overview of the sustainability initiatives at the St. John's campus of Memorial University in Newfoundland and Labrador (Canada). The key initiatives include setting a realistic goal for energy efficiency, becoming carbon neutral, and conducting various research and outreach projects related to sustainability. As…

Why Reference to the Past Is Difficult for Agrammatic Speakers

ERIC Educational Resources Information Center

Bastiaanse, Roelien

2013-01-01

Many studies have shown that verb inflections are difficult to produce for agrammatic aphasic speakers: they are frequently omitted and substituted. The present article gives an overview of our search to understanding why this is the case. The hypothesis is that grammatical morphology referring to the past is selectively impaired in agrammatic…

Exploring Biliteracy Developments among Asian Women in Diasporas: The Case of Taiwan

ERIC Educational Resources Information Center

Lee, Yu-Hsiu Hugo

2010-01-01

This study presents a broad overview of diasporic biliteracy developments in immigrant women after examining observation data in one Taiwanese community. Methodologies include a mixture of narrative inquiry with some ethnographic methods. Fifteen Asian women in diaspora, two Burmese, one Cambodian, one Filipino, four Indonesians, three Thai and…

Identities of Dis/Ability and Music

ERIC Educational Resources Information Center

Watts, Michael; Ridley, Barbara

2012-01-01

Centring on a small-scale capability-based case study of music provision for adults with profound dis/abilities, this paper considers the significance of music and music education in people's lives. It offers a philosophical defence of music's importance in enjoying a truly human life and then, drawing on an overview of the work of dis/abled…

The Perceived Impact of External Evaluation: The System, Organisation and Individual Levels-Estonian Case

ERIC Educational Resources Information Center

Seema, Riin; Udam, Maiki; Mattisen, Heli; Lauri, Liia

2017-01-01

The purpose of this article is to provide an overview of how the employees of higher education institutions perceive the impact of external evaluations. The study was conducted using the concurrent mixed method and involved 361 employees from Estonian universities and professional higher education institutions. The results indicated that…

Raising the Degree of Service-Orientation of a SOA-based Software System: A Case Study

DTIC Science & Technology

2009-12-01

protocols, as well as executable processes that can be compiled into runtime scripts” [2] The Business Process Modeling Notation ( BPMN ) provides a...Notation ( BPMN ) 1.2. Jan. 2009. URL: http://www.omg.org/spec/ BPMN /1.2/ [25] .NET Framework Developer Center. .NET Remoting Overview. 2003. URL: http

Leadership and Gender: Conclusions Drawn from Wildrose School

ERIC Educational Resources Information Center

Burns, Amy M.

2006-01-01

In this article, I present the findings of a single-site case study which examined the role of gender in constituent group perceptions of effective female leadership. First, a brief description of the Wildrose School community context is presented followed by an overview of relevant literature on female leadership. The emergent themes regarding…

Small Town Renewal: Overview and Case Studies.

ERIC Educational Resources Information Center

Kenyon, Peter, Ed.; Black, Alan, Ed.

Many small, inland, and remote Australian rural communities continue to lose population and businesses, a trend that has intensified over the last 2 decades. Mean age continues to rise, while the 15-24 age group contracts dramatically. Such declining demographics are caused by the stress and uncertainty of volatile world commodity markets, as well…

Recent trends in preservative treatments for timber bridges

Treesearch

James P. Wacker

2004-01-01

An overview of wood preservatives currently used for timber bridges is presented through a series of case studies from different regions of the United States. New wood species and preservative treatment options for timber bridges have made choosing the appropriate preservative more complicated. The compatibility of wood species and preservative treatment is often...

Case Management: Service or Symptom?

ERIC Educational Resources Information Center

Netting, F. Ellen

1992-01-01

Provides overview of case management, its history, and contemporary models. Examines challenges that case management poses for social work profession: covering up issue that health and human services delivery system is nonsystem; maintaining client-centered perspective in cost-obsessed environment; dealing with quality control; coping with…

A case study of the influences of audience and purpose on the composing processes of an engineer

NASA Technical Reports Server (NTRS)

Stalnaker, B. J.

1981-01-01

The design and preliminary findings of a study of composing processes (on the job) of engineers, managers, and scientists is presented. The influences of audience and purpose on the composing process of engineers was of concern; specifically, the cognitive processes, physical behaviors, and factors that influence the evoluton of a piece of writing. An overview of the study, related literature, outlines of research design, and preliminary findings from a case study of engineers are given. It is suggested that teaching be adapted to help students learn to represent rhetorical problems to guide composing for effective writing.

Theoretical pluralism in psychoanalytic case studies.

PubMed

Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M B D

2015-01-01

The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or "Classical psychoanalysis" dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals.

Theoretical pluralism in psychoanalytic case studies

PubMed Central

Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M.; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M. B. D.

2015-01-01

The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or “Classical psychoanalysis” dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals. PMID:26483725

A Guide for Designing and Implementing a Case Processing System for Child Support Enforcement.

ERIC Educational Resources Information Center

Office of Child Support Enforcement (DHHS), Washington, DC.

This document was written to provide state and local child support offices with help in refining their case processing systems. The guide is divided into five chapters. Chapter I, Case Processing Overview, defines case processing and the case processing functions and provides a narrative description and graphic illustration of the processes…

Study protocol and overview of the literature on long-term health and quality of life outcomes in patients treated in adolescence for scoliosis with therapeutic exercises.

PubMed

Plaszewski, Maciej; Kotwicki, Tomasz; Chwala, Wieslaw; Terech, Jacek; Cieśliński, Igor

2015-01-01

Scoliosis, the most prevalent orthopaedic condition affecting children and adolescents, may have lasting physical, psychological and social consequences. With limited evidence-base, scoliosis-specific exercise therapies are an option. An overview of the subject and description of a long-term follow-up study including adults who in adolescence were treated with a scoliosis-specific exercise programme investigating the association of the exercise regime with present physical activity, physical functioning and subjective wellbeing. To the authors' best knowledge, this is the first long-term outcome study on scoliosis-specific exercises, in opposition to a number of studies in adults who were braced or treated surgically in adolescence. Observational, registry-based case-control study. Adult subjects who in adolescence were treated with an exercise programme or were under observation are invited. Spine and trunk deformity, respiratory function, physical capacity and trunk muscles' function are measured. Health-related quality of life with generic and condition-specific instruments, general mental health, depression and anxiety symptoms, disability due to low back problems and physical activity are assessed. The report is believed to provide the readers with an overview of this controversial aspect of rehabilitation, and that the proposed protocol will assist researchers designing their studies.

Overview of the Hydrogen Financial Analysis Scenario Tool (H2FAST); NREL (National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melaina, Marc; Bush, Brian; Penev, Michael

This presentation provides an introduction to the Hydrogen Financial Analysis Scenario Tool (H2FAST) and includes an overview of each of the three versions of H2FAST: the Web tool, the Excel spreadsheet version, and the beta version of the H2FAST Business Case Scenario tool.

The Law on Reduction In Force: An Overview and Update.

ERIC Educational Resources Information Center

Zirkel, Perry A.

This chapter provides an overview of legislation and litigation relating to reduction in force (RIF) with a focus on cases decided since 1980. State statutes continue to be the primary source of the law concerning RIF, so a table is provided for these statutes and their various provisions. These statutes include the dismissla-type, and the less…

Evidence-based nursing practice: both state of the art in general and specific to pressure sores.

PubMed

Buss, I C; Halfens, R J; Abu-Saad, H H; Kok, G

1999-01-01

The importance of research-based practice in nursing has been frequently stressed, and a number of nursing studies have been conducted whose results enable nursing to improve knowledge and practice. This study reports a literature review in which the current status of knowledge and research utilization with regard to pressure sores is described. This review first gives an overview of studies on knowledge utilization in general and shows that the spontaneous diffusion of knowledge is inappropriate. Furthermore, an overview of planned research utilization activities focusing on pressure sore prevention and treatment in nursing is presented. The results of these studies show that planned research utilization activities performed in individual organizations lead to positive outcomes in almost all cases. Therefore, it could be concluded that implementing planned research utilization activities in individual health care institutions seems to be an effective strategy to decrease pressure sore incidence and prevalence rates.

Strategic Integration of Open Educational Resources in Higher Education

NASA Astrophysics Data System (ADS)

Schaffert, Sandra

Open Educational Resources (OERs) can be seen as social movement but are also implemented as strategic measures in higher education institutions (HEIs). This chapter describes the current aims and experiences of OERs in HEIs. Starting with definitions and milestones in respect of the current status, this chapter gives an overview of projects and implementation objectives and it describes two concrete case studies, i.e., the Massachusetts Institute of Technology Open CourseWare project and the OpenLearn project at the Open University in the United Kingdom. The aim of this chapter is to give a comprehensive overview to decision makers and policy drivers within higher education organizations, and thus it develops a blueprint of an implementation model.

Thirty Years of Music and Drama Education in the Madeira Island: Facing Future Challenges

ERIC Educational Resources Information Center

Mota, Graça; Abreu, Liliana

2014-01-01

In this paper we give an overview of relevant findings of a three years long case study that was carried out in the Madeira Island, Portugal. It addresses a thirty years old project in music and drama education in primary schools, which involves all children within the school curriculum, but also in extra-curriculum activities. The study used…

Listeriosis in the far South of Brazil: neglected infection?

PubMed

Blum-Menezes, Dulcinéa; Deliberalli, Ivânia; Bittencourt, Najara Carneiro; Couto, Carlus Augustu Tavares do; Barbosa, Liana Nunes; Santos, Alessandro Marques dos; Pinto, Gabriel Godinho

2013-01-01

Listeriosis is an under-diagnosed and under-reported infection; however, listeriosis is not a compulsorily notifiable disease in Brazil. We provide an overview of the rates of listeriosis in the United States of America (USA), Europe, Latin America, and Brazil during the past decade. We also report a case of miscarriage caused by listeriosis in which there was no suspicion of this infection. This overview and the case we report serve as reminders of the often-neglected threat of listeriosis and its potential to cause miscarriage while highlighting the necessity of recognizing listeriosis as a compulsorily notifiable disease in Brazil.

Force Sensing Resistor (FSR): a brief overview and the low-cost sensor for active compliance control

NASA Astrophysics Data System (ADS)

Sadun, A. S.; Jalani, J.; Sukor, J. A.

2016-07-01

Force Sensing Resistors (FSR) sensors are devices that allow measuring static and dynamic forces applied to a contact surface. Their range of responses is basically depending on the variation of its electric resistance. In general, Flexiforce and Interlink are two common types of FSR sensors that are available, cheap and easily found in the market. Studies have shown that the FSR sensors are usually applied for robotic grippers and for biomechanical fields. This paper provides a brief overview of the application of the FSR sensors. Subsequently, two different set of experiments are carried out to test the effectiveness of the Flexiforce and Interlink sensors. First, the hardness detector system (Case Study A) and second, the force-position control system (Case Study B). The hardware used for the experiment was developed from low-cost materials. The results revealed that both FSR sensors are sufficient and reliable to provide a good sensing modality particularly for measuring force. Apart from the low-cost sensors, essentially, the FSR sensors are very useful devices that able to provide a good active compliance control, particularly for the grasping robotic hand.

Human urine-based therapeutics in Spain from the early 20th century to the present: a historical literature overview and a present-day case study.

PubMed

Vallejo, José Ramón; Aparicio Mena, Alfonso J; González, José Antonio

2017-06-01

Human urine is currently the subject of biomedical investigations as a potential therapeutic resource and it continues to be used in remedies in different cultures and societies, including the Spanish culture. In this study we gather etnomedical knowledge about urotherapy and determine their associated symbolisms in Spain. A literature overview and a case study were carried out to compile urine-based remedies and as a direct analysis of symbolic systems. Urotherapy is widespread in Spanish folk medicine. Among the 204 collected remedies, those related to treatment of diseases or skin conditions predominate (63%). Remedies have been reported for the treatment of skin diseases such as eczema, chloasma, alopecia, etc. to treat or alleviate burns, chilblains, wounds or skin chapping, and as a treatment of venomous bites. Most of the collected remedies have an associated naturalist symbolism, based on local traditions and the transmission of empirical initial knowledge. The use of urine in Spain is a result of the interaction of two types of practice: a local and traditional urotherapy, rural and with a utilitarian purpose, and a technical urotherapy, limited to an urban environment and a naturopathic medicine.

What ethics for case managers? Literature review and discussion.

PubMed

Corvol, Aline; Moutel, Grégoire; Somme, Dominique

2016-11-01

Little is known about case managers' ethical issues and professional values. This article presents an overview of ethical issues in case managers' current practice. Findings are examined in the light of nursing ethics, social work ethics and principle-based biomedical ethics. A systematic literature review was performed to identify and analyse empirical studies concerning ethical issues in case management programmes. It was completed by systematic content analysis of case managers' national codes of ethics. Only nine empirical studies were identified, eight of them from North America. The main dilemmas were how to balance system goals against the client's interest and client protection against autonomy. Professional codes of ethics shared important similarities, but offered different responses to these two dilemmas. We discuss the respective roles of professional and organizational ethics. Further lines of research are suggested. © The Author(s) 2015.

Utility Bill Calibration Test Cases | Buildings | NREL

Science.gov Websites

illustrates the utility bill calibration test cases in BESTEST-EX. In these cases, participants are given software results have been generated. This diagram provides an overview of the BESTEST-EX utility bill calibration case process. On the left side of the diagram is a box labeled "BESTEST-EX Document"

Passive Endwall Treatments for Enhancing Stability

NASA Technical Reports Server (NTRS)

Hathaway, Michael D.

2007-01-01

These lecture notes were presented at the von Karman Institutes lecture series on Advances in Axial Compressor Aerodynamics, May 2006. They provide a fairly extensive overview of what's been learned from numerous investigations of various passive casing endwall technologies that have been proposed for alleviating the stall limiting physics associated with the compressor endwall flow field. The lecture notes are organized to give an appreciation for the inventiveness and understanding of the earliest compressor technologists and to provide a coherent thread of understanding that has arisen out of the early investigations. As such the lecture notes begin with a historical overview of casing treatments from their infancy through the earliest proposed concepts involving blowing, suction and flow recirculation. A summary of lessons learned from these early investigations is provided at the end of this section. The lecture notes then provide a somewhat more in-depth overview of recent advancements in the development of passive casing treatments from the late 1990's through 2006, including advancements in understanding the flow mechanism of circumferential groove casing treatments, and the development of discrete tip injection and self-recirculating casing treatments. At the conclusion of the lecture notes a final summary of lessons learned throughout the history of the development of passive casing treatments is provided. Finally, a list of future needs is given. It is hoped that these lecture notes will be a useful reference for future research endeavors to improve our understanding of the fluid physics of passive casing treatments and how they act to enhance compressor stability, and that they will perhaps provide a springboard for future research activities in this area of interest

[The syndrome of Cotard: an overview].

PubMed

Van den Eynde, F; Debruyne, H; Portzky, M; De Saedeleer, S; Audenaert, K

2008-01-01

There is increasing controversy about whether psychiatric illnesses should be divided into categories. One of the reasons is that such a categorial system, by its very nature, cannot provide a detailed description of specific psychopathological symptoms. A patient with Cotard's syndrome, for instance, is characterised by a nihilistic delusion relating to his own body and the syndrome does not fit into any one category. We report on a case of Cotard's syndrome encountered at our clinic. To provide an overview of the characteristics of Cotard's syndrome, including its history, phenomenology, pathogenesis and treatment. A Medline search was conducted for the period 1980-2006 using the search term 'Cotard$'. This resulted in 68 publications, of which 18 were not used. Cross-references were used as well. Cotard's syndrome cannot be fitted unambiguously into any one category of the current classification system. Current evidence regarding Cotard's syndrome is based mainly on case studies and therefore no clarity can be obtained about the various aspects of the syndrome, such as prevalence, pathogenesis, treatment.

Trimble Use Case Information : A Presentation to DOT Adjacent Band Compatibility Workshop #2

DOT National Transportation Integrated Search

2014-12-04

Trimble Use Case Overview: Heavy Civil Construction - Planning, Designing, Building and Operating: Enhanced information, decision making and control across the entire project lifecycle, generating benefits including: - Faster Completion - Reduced Fue...

Headache (chronic tension-type)

PubMed Central

2016-01-01

Introduction Chronic tension-type headache (CTTH) is a disorder that evolves from episodic tension-type headache, with daily, or very frequent, episodes of headache lasting hours or they may be continuous. It affects up to 4% of the general population, and is more prevalent in women (up to 65% of cases). Methods and outcomes We conducted a systematic overview, aiming to answer the following clinical questions: What are the effects of drug treatments for CTTH? What are the effects of non-drug treatments for CTTH? We searched: Medline, Embase, The Cochrane Library, and other important databases up to December 2013 (BMJ Clinical Evidence overviews are updated periodically; please check our website for the most up-to-date version of this overview). Results At this update, searching of electronic databases retrieved 125 studies. After deduplication, 77 records were screened for inclusion in the overview. Appraisal of titles and abstracts led to the exclusion of 56 studies and the further review of 21 full publications. Of the 21 full articles evaluated, three systematic reviews and one RCT were included at this update. We performed a GRADE evaluation for 15 PICO combinations. Conclusions In this systematic overview, we categorised the efficacy for 12 interventions based on information about the effectiveness and safety of non-drug treatments acupuncture and cognitive behavioural therapy (CBT), as well as the drug treatments amitriptyline, anticonvulsant drugs (sodium valproate, topiramate, or gabapentin), benzodiazepines, botulinum toxin, noradrenergic and specific serotonergic antidepressants (mirtazapine), NSAIDs (e.g. ibuprofen); opioid analgesics (e.g. codeine), paracetamol, serotonin re-uptake inhibitor antidepressants (SSRIs, SNRIs), and tricyclic antidepressants (other than amitriptyline). PMID:26859719

“Overview and Evaluation of AQMEII Phase 2 Coupled ...

EPA Pesticide Factsheets

This presentation provides an overview of the second phase of the Air Quality Model Evaluation International Initative (AQMEII). Activities in this phase are focused on the application and evaluation of coupled meteorology-chemistry models to assess how well these models can simulate the observed spatio-temporal variability in the optical and radiative characteristics of atmospheric aerosols and associated feedbacks among aerosols, radiation, clouds, and precipitation. To this end, these modeling systems are being applied for annual simulations over both North America and Europe using common emissions and boundary conditions for all modeling groups. We present an overview of these common input datasets, observational datasets for model evaluation, and case studies for diagnostic evaluation. In addition to this overview, we also present results from AQMEII Phase 2 WRF/CMAQ simulations over North America for both 2006 and 2010. The time period between 2006 and 2010 was characterized by a 35% reduction in U.S. SO2 emissions and 20% reduction in U.S. NOx emissions, providing an opportunity for dynamic model evaluation by investigating the impact of emission reductions on ambient concentrations as well as aerosol/radiation feedback effects. We present results of this dynamic evaluation. We also present a brief overview of initial results from WRF-Chem and GEM-MACH simulations performed for the same time period and domain as part of AQMEII Phase 2. The National Exposu

An Overview of Maxillofacial Trauma in Oral and Maxillofacial Tertiary Trauma Centre, Queen Elizabeth Hospital, Kota Kinabalu, Sabah

PubMed Central

Lee, Chee Wei; Foo, Qi Chao; Wong, Ling Vuan; Leung, Yiu Yan

2016-01-01

The aims of this study were to provide an overview of maxillofacial trauma and its relationship to patient's demographic data and alcohol consumption within the state of Sabah. It was a retrospective study of maxillofacial trauma cases treated by Oral and Maxillofacial Surgery Department, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, from January 1, 2009, until December 31, 2013. A total of 630 maxillofacial trauma cases were included. Details of the trauma were collected from patients' record, including patients' cause of injuries, injuries suffered, treatment indications, and treatment received. Patients' demographic data (age, gender), alcohol consumption in relation to causes, and type of maxillofacial injury were analyzed. There were 538 male (85.4%) and 92 female (14.6%) patients (ratio: 5.8:1), with mean age of 31.0 years. Most common causes of maxillofacial injury were motor vehicle accident (MVA; 66.3%), followed by fall (12.4%) and assault (11.6%). Motorcyclists made up more than half of the total cases (53.1%). Cases referred were primarily due to soft-tissue injury (458 cases). Other cases were dentoalveolar and maxillofacial bone fractures. Treatment provided for the fractures included open reduction and internal fixation (22.9%), closed reduction (28.7%), and conservative management (48.4%). Toilet and suturing were done for all patients with soft-tissue injury. Maxillofacial trauma is a major problem in Sabah. It affects mostly males in the age group of 21 to 30 years. Most of the MVA patients were motorcyclists. Mandibular fracture with parasymphysis involvement recorded the highest number. Most of the patients preferred conservative management, probably due to financial and logistic issue. PMID:28210403

Rational Decisionmaking in Higher Education. An NCHEMS Executive Overview.

ERIC Educational Resources Information Center

Chaffee, Ellen Earle

Five models of organizational decision-making are described, and a case study of the rational model as seen in the budget process at Stanford University during the 1970s is presented. Several issues are addressed to help administrators who are interested in increasing the organization's rational decision-making. The five models are as follows: the…

Computer simulation modeling of recreation use: Current status, case studies, and future directions

Treesearch

David N. Cole

2005-01-01

This report compiles information about recent progress in the application of computer simulation modeling to planning and management of recreation use, particularly in parks and wilderness. Early modeling efforts are described in a chapter that provides an historical perspective. Another chapter provides an overview of modeling options, common data input requirements,...

Accounting in the Context of Its Environment: The Colombian Case.

ERIC Educational Resources Information Center

Laribee, Stephen F.; Laribee, Janet F.

This paper provides a study of the evolution of the accounting system in the country of Columbia, South America, in light of the conflict between cultural values, other environmental factors, and the financial information generated. The paper begins with an overview of Colombia's political history as well as its economic and social changes during…

How Schools Can Help Combat Student Eating Disorders. Anorexia Nervosa and Bulimia.

ERIC Educational Resources Information Center

Levine, Michael P.

This book presents a comprehensive review of anorexia nervosa and bulimia and the roles that schools can have in preventing, identifying, and treating these disorders. Chapter 1 provides an overview of student eating disorders and presents a case study of a high school student with an eating disorder. Chapter 2 discusses the nature of anorexia…

Integrating E-Learning 2.0 into Online Courses

ERIC Educational Resources Information Center

Yuen, Steve Chi-Yin

2014-01-01

This paper provides an overview of e-learning 2.0 concepts and presents a case study that involves the design, development, and teaching of two online courses based on e-learning 2.0 concepts. The design and the construction of e-learning 2.0 courses, and their effects on the students' learning experience are examined. In addition, students'…

User-Centered Design and Usability Testing of a Web Site: An Illustrative Case Study.

ERIC Educational Resources Information Center

Corry, Michael D.; Frick, Theodore W.; Hansen, Lisa

1997-01-01

Presents an overview of user-centered design and usability testing. Describes a Web site evaluation project at a university, the iterative process of rapid prototyping and usability testing, and how the findings helped to improve the design. Discusses recommendations for university Web site design and reflects on problems faced in usability…

Increasing Teachers' Use of Evidence-Based Classroom Management Strategies through Consultation: Overview and Case Studies

ERIC Educational Resources Information Center

MacSuga, Ashley S.; Simonsen, Brandi

2011-01-01

Many classroom teachers are faced with challenging student behaviors that impact their ability to facilitate learning in productive, safe environments. At the same time, high-stakes testing, increased emphasis on evidence-based instruction, data-based decision making, and response-to-intervention models have put heavy demands on teacher time and…

Evaluation of Dam Decommissioning in an Ice-Affected River: Case Study

DTIC Science & Technology

2007-09-01

Abdul-Mohsen 2005 and Kuby et al. 2005). Conyngham et al. (2006) provide an overview of the ecological and engi- neering aspects of dam decommissioning...2007) CRREL Ice Jam Database (http://www.crrel.usace.army.mil/ierd/ijdb/), accessed March 2007. Kuby , M.J., W.F. Fagan, C.S. ReVelle, W.L. Graf (2005

Managing e-Books at the University of Derby: A Case Study

ERIC Educational Resources Information Center

Wilkins, Valerie

2007-01-01

Purpose: The purpose of the paper is to describe the practical experience of managing e-books in an academic library. Design/methodology/approach: An overview of the three main e-book collections used (netLibrary, Taylor & Francis, and Ebook Library via Dawson) is provided, along with details such as the acquisition, cataloguing and…

Globalisation and Internationalisation of Teacher Education: A Comparative Case Study of Canada and Greater China

ERIC Educational Resources Information Center

Larsen, Marianne A.

2016-01-01

This article begins with a brief overview of the relationship between globalisation and the internationalisation of higher education. This serves as a backdrop for the focus of the article, which is the internationalisation of teacher education. In order to see the diverse ways that teacher education programmes have been internationalised over the…

Case Studies on Technical and Vocational Education in Asia and the Pacific. An Overview.

ERIC Educational Resources Information Center

Haas, Adrian

A project considered issues that might contribute toward raising the status of technical and vocational education (TVE) in Asia and the Pacific region. It also provided a review of TVE in Australia, Bangladesh, China, Fiji, India, Indonesia, Iran, Japan, Republic of Korea, Malaysia, Pakistan, Thailand, and Vietnam. Researchers involved in the…

Sustainable tourism development: the case study of Antalya, Turkey

Treesearch

Latif Gurkan Kaya; Richard Smardon

2001-01-01

This paper discuss ideas about how tourism can be made base for sustainable tourism development in Antalya, Turkey. The introduction is a general overview of sustainable tourism development in coastal areas. The paper also addresses the role of NGOs in the course of development. Information is given about coastal tourism facilities in Turkey. Finally, sustainable...

The Case of Educational Peacebuilding inside the United Nations Universities: A Review and Critique

ERIC Educational Resources Information Center

Kester, Kevin

2017-01-01

This article examines higher education for peace inside the United Nations (UN). It offers an overview and synthesis of core concepts, organizing frameworks and theoretical premises in the field of peace and conflict studies (PACS) higher education and in the UN universities in particular, as the field aspires toward transformative learning and…

Caring for Kids in Communities: Using Mentorship, Peer Support, & Student Leadership Programs in Schools. Counterpoint.

ERIC Educational Resources Information Center

Ellis, Julia; Small-McGinley, Jan; De Fabrizio, Lucy

This book invites schools to consider the use of mentorship, peer support, and student leadership programs to positively support the growth and learning of all students. It presents research on successful K-12 programs and case studies of individual programs and people. Eighteen chapters are: (1) "Introduction and Overview"; (2)…

Lazarus's BASIC ID: Making Initial Client Assessments Using Q-Sorts.

ERIC Educational Resources Information Center

Miller, Mark J.

1987-01-01

Presents overview of Lazarus's multimodal therapy model and the Q-sort, an observer-evaluation scoring instrument. Outlines feasibility of integrating Q-sort within multimodal model. Describes both a preliminary attempt using expert raters to categorize Q-sort cards within the model and a case study on how to assess client by incorporating Q-sort…

Financing Secondary Education in the Philippines. Financing of Educational Systems: Specific Case Studies - 11. IIEP Research Report: 4.

ERIC Educational Resources Information Center

Cruz, Leopoldo; Calado, Rene R.

This report describes the Philippine secondary educational system, with particular emphasis on the system of financing different types of secondary schools. Part 1 presents an introductory overview of the Philippine educational system, emphasizing the secondary school system in particular. Part 2 describes the methods of financing different types…

Quality Assurance in an International Higher Education Area: A Summary of a Case-Study Approach and Comparative Analysis

ERIC Educational Resources Information Center

Bernhard, Andrea

2012-01-01

Transparency and comparability of higher education institutions especially in terms of their academic programmes and research activities are important issues for today's working environment. This paper is an overview of a recently completed PhD thesis which outlines examples of selected Organization for Economic Co-operation and Development…

"Streams of Influence" in Student Affairs: A Renewed Emphasis on Leadership Education

ERIC Educational Resources Information Center

Gigliotti, Ralph A.

2015-01-01

This case study presents an overview of the development of a new Office for Leadership Programs at Villanova University, housed under the Office of Student Development. Adapting Kingdon's (1984) public policy model to the creation of new initiatives in student affairs, this article offers a conceptual framework for the design of new student…

Computer Science Education in North-Rhine Westphalia, Germany--A Case Study

ERIC Educational Resources Information Center

Knobelsdorf, Maria; Magenheim, Johannes; Brinda, Torsten; Engbring, Dieter; Humbert, Ludger; Pasternak, Arno; Schroeder, Ulrik; Thomas, Marco; Vahrenhold, Jan

2015-01-01

In North-Rhine Westphalia, the most populated state in Germany, Computer Science (CS) has been taught in secondary schools since the early 1970s. This article provides an overview of the past and current situation of CS education in North-Rhine Westphalia, including lessons learned through efforts to introduce and to maintain CS in secondary…

Grant Development for Large Scale Research Proposals: An Overview and Case Study

ERIC Educational Resources Information Center

Goodman, Ira S.

2011-01-01

With some NIH pay lines running at or below the 10th percentile, and funding becoming scarce for large science grants, new approaches are necessary to secure large interdisciplinary grant awards. The UCSD Moores Cancer Center has developed a team approach, starting with the identification of a competitive opportunity and progressing to the…

Ethics--Business Educators Teach Students To Do the Right Thing!

ERIC Educational Resources Information Center

Keying In, 1997

1997-01-01

This issue focuses on teaching ethics in business education programs. Exploring the teaching of ethics in both high school and college, the newsletter first presents an overview of ethics and the study of ethics and makes a case for teaching ethics in business education courses. Following a short commentary on the difficulty of teaching ethics is…

SERA Scenarios of Early Market Fuel Cell Electric Vehicle Introductions: Modeling Framework, Regional Markets, and Station Clustering; NREL (National Renewable Energy Laboratory)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melaina, M.

This presentation provides an overview of the Scenario Evaluation and Regionalization Analysis (SERA) model, describes the methodology for developing scenarios for hydrogen infrastructure development, outlines an example "Hydrogen Success" scenario, and discusses detailed scenario metrics for a particular case study region, the Northeast Corridor.

A Seven-Step Process To Align Curriculum with Oregon State Content Standards.

ERIC Educational Resources Information Center

Golden, Nancy; Lane, Marilyn

1998-01-01

The University of Oregon (UO) and Captain Robert Gray Elementary School formed a partnership where UO students used the elementary school as a case study for curriculum research. This document gives an overview of the 7-step process the students used to align the school's curriculum with Oregon's content and performance standards. The text opens…

Multitiered Support Framework for Teachers' Classroom-Management Practices: Overview and Case Study of Building the Triangle for Teachers

ERIC Educational Resources Information Center

Simonsen, Brandi; MacSuga-Gage, Ashley S.; Briere, Donald E.; Freeman, Jennifer; Myers, Diane; Scott, Terrance M.; Sugai, George

2014-01-01

Many teachers enter the field without sufficient training in classroom management and continue to experience challenges throughout their careers. Therefore, school-based leaders need a multi-tiered support (MTS) framework to (a) provide training to all teachers in classroom management (Tier 1), (b) identify teachers who require additional…

Technical and Vocational Education and Training in Fiji--An Overview. Case Studies on Technical and Vocational Education in Asia and the Pacific.

ERIC Educational Resources Information Center

Delailomaloma, N. H.

The Fiji economy has undergone structural transformation as the importance of agriculture, construction, social and community services, finance, and insurance declined, whereas that of hotels and catering, transportation, communication, and mining rose. Capacity utilization, including absorption of already trained and educated people into…

Building Physics Test Cases | Buildings | NREL

Science.gov Websites

building physics test cases in BESTEST-EX. In these cases, the model inputs that describe the house are programs. This diagram provides an overview of the BESTEST-EX physics case process. On the left side of the diagram is a box labeled "BESTEST-EX Document" with a list that contains two bulleted items. The

Use of EPR to Solve Biochemical Problems

PubMed Central

Sahu, Indra D.; McCarrick, Robert M.; Lorigan, Gary A.

2013-01-01

EPR spectroscopy is a very powerful biophysical tool that can provide valuable structural and dynamic information on a wide variety of biological systems. The intent of this review is to provide a general overview for biochemists and biological researchers on the most commonly used EPR methods and how these techniques can be used to answer important biological questions. The topics discussed could easily fill one or more textbooks; thus, we present a brief background on several important biological EPR techniques and an overview of several interesting studies that have successfully used EPR to solve pertinent biological problems. The review consists of the following sections: an introduction to EPR techniques, spin labeling methods, and studies of naturally occurring organic radicals and EPR active transition metal systems which are presented as a series of case studies in which EPR spectroscopy has been used to greatly further our understanding of several important biological systems. PMID:23961941

An Ontology for Modeling Complex Inter-relational Organizations

NASA Astrophysics Data System (ADS)

Wautelet, Yves; Neysen, Nicolas; Kolp, Manuel

This paper presents an ontology for organizational modeling through multiple complementary aspects. The primary goal of the ontology is to dispose of an adequate set of related concepts for studying complex organizations involved in a lot of relationships at the same time. In this paper, we define complex organizations as networked organizations involved in a market eco-system that are playing several roles simultaneously. In such a context, traditional approaches focus on the macro analytic level of transactions; this is supplemented here with a micro analytic study of the actors' rationale. At first, the paper overviews enterprise ontologies literature to position our proposal and exposes its contributions and limitations. The ontology is then brought to an advanced level of formalization: a meta-model in the form of a UML class diagram allows to overview the ontology concepts and their relationships which are formally defined. Finally, the paper presents the case study on which the ontology has been validated.

From Education to Work: Cross-National Perspectives. Revisitations of Papers Delivered at the Conference at the University of Toronto (April 18-20, 1996).

ERIC Educational Resources Information Center

Heinz, Walter R., Ed.

This volume is composed of 13 comparable longitudinal studies that draw on survey data and case studies of young people in Canada, Germany, Great Britain, and the United States. "Introduction: Transitions to Employment in a Cross-National Perspective" (Walter R. Heinz) provides a context and an overview. Part I has four chapters that…

An overview of history, pathogenesis and treatment of perforated peptic ulcer disease with evaluation of prognostic scoring in adults.

PubMed

Prabhu, V; Shivani, A

2014-01-01

Peptic ulcer disease including both gastric and duodenal ulcer form a substantial part of patients seeking surgical opinion world-wide. The concept of acid in peptic ulcer disease, which was the basis of treatment of peptic ulcer was revolutionized by the discovery of H2-receptor antagonists, that led to the principle of acid suppression therapy for duodenal ulcer which followed decades of preference for surgical interventions in the form of gastric resections, vagotomy etc., After the discovery of Helicobacter pylori organism as the causative factor a triple drug regime was identified to treat peptic disease which was further modified to sequential therapy to avoid antibiotic resistance. This recognition has not concluded the chapter on peptic ulcers. The management of ulcer disease and its complications remain a surgical challenge. All the materials for this review have been accessed from various internet search engines. The references have been narrowed down to 34 by excluding cross references, duplicated citations, pediatric studies, case reports, iatrogenic and malignant perforations and including microbiological, immunohistochemistry references and studies with more than a sample size of ten. Case control, cohort studies, prospective/retrospective, metaanalytical studies were preferred in that order. This article attempts to take an overview of all aspects of the management of peptic ulcer.

An Overview of History, Pathogenesis and Treatment of Perforated Peptic Ulcer Disease with Evaluation of Prognostic Scoring in Adults

PubMed Central

Prabhu, V; Shivani, A

2014-01-01

Peptic ulcer disease including both gastric and duodenal ulcer form a substantial part of patients seeking surgical opinion world-wide. The concept of acid in peptic ulcer disease, which was the basis of treatment of peptic ulcer was revolutionized by the discovery of H2-receptor antagonists, that led to the principle of acid suppression therapy for duodenal ulcer which followed decades of preference for surgical interventions in the form of gastric resections, vagotomy etc., After the discovery of Helicobacter pylori organism as the causative factor a triple drug regime was identified to treat peptic disease which was further modified to sequential therapy to avoid antibiotic resistance. This recognition has not concluded the chapter on peptic ulcers. The management of ulcer disease and its complications remain a surgical challenge. All the materials for this review have been accessed from various internet search engines. The references have been narrowed down to 34 by excluding cross references, duplicated citations, pediatric studies, case reports, iatrogenic and malignant perforations and including microbiological, immunohistochemistry references and studies with more than a sample size of ten. Case control, cohort studies, prospective/retrospective, metaanalytical studies were preferred in that order. This article attempts to take an overview of all aspects of the management of peptic ulcer. PMID:24669326

Reversible severe hepatitis in anorexia nervosa: a case report and overview.

PubMed

Ramsoekh, Dewkoemar; Taimr, Pavel; Vanwolleghem, Thomas

2014-04-01

Mildly elevated transaminases are often observed in anorexia nervosa patients, but severe hepatitis is less common. We suggest that hypoperfusion is the pathogenetic factor that causes severe hepatitis in a patient with a very poor nutritional status and present an overview of previous case reports. In our patient, early initiation of intravenous fluids resulted in rapid recovery of the liver test abnormalities, despite minimal oral caloric intake, the refusal of enteral feeding and the development of a hypoglycemic coma. Two months after admission, transaminases had normalized. Reversible severe hepatitis has been described in most of the cases, with only one anorexia nervosa-related fatal hepatitis. In general, both adequate hydration and gradual enteral feeding with monitoring of electrolytes are essential in the management of anorexia patients with severe hepatitis.

Gravity measurement, processing and evaluation: Test cases de Peel and South Limburg

NASA Astrophysics Data System (ADS)

Nohlmans, Ron

1990-05-01

A general overview of the process of the measurement and the adjustment of a gravity network and the computation of some output parameters of gravimetry, gravity values, gravity anomalies and mean block anomalies, is given. An overview of developments in gravimetry, globally and in the Netherlands, until now is given. The basic theory of relative gravity measurements is studied and a description of the most commonly used instrument, the LaCoste and Romberg gravimeter is given. The surveys done in the scope of this study are descibed. A more detailed impression of the adjustment procedure and the results of the adjustment are given. A closer look is taken at the more geophysical side of gravimetry: gravity reduction, the computation of anomalies and the correlation with elevation. The interpolation of gravity and the covariance of gravity anomalies are addressed.

The influence of posttraumatic stress disorder, depression, and sensory processing patterns on occupational engagement: a case study.

PubMed

Champagne, Tina

2011-01-01

The purpose of this article is to provide a brief overview of how Posttraumatic Stress Disorder (PTSD), Depression, and Sensory Processing patterns influence occupational engagement, including work performance. Interventions and outcomes of the Sensory Modulation Program and approaches from Cognitive Behavior Therapy (CBT) are reviewed through single case exploration with a 42 year-old woman in outpatient services. The marked increase in occupational engagement and improved work performance in this single case review demonstrates the need for more research on the use of the Sensory Modulation Program and approaches from CBT with populations with PTSD, Depression, and Sensory Processing disorder.

An overview of the National Earthquake Information Center acquisition software system, Edge/Continuous Waveform Buffer

USGS Publications Warehouse

Patton, John M.; Ketchum, David C.; Guy, Michelle R.

2015-11-02

This document provides an overview of the capabilities, design, and use cases of the data acquisition and archiving subsystem at the U.S. Geological Survey National Earthquake Information Center. The Edge and Continuous Waveform Buffer software supports the National Earthquake Information Center’s worldwide earthquake monitoring mission in direct station data acquisition, data import, short- and long-term data archiving, data distribution, query services, and playback, among other capabilities. The software design and architecture can be configured to support acquisition and (or) archiving use cases. The software continues to be developed in order to expand the acquisition, storage, and distribution capabilities.

Clinical overview: a framework for analysis.

PubMed

Bossen, Claus; Jensen, Lotte G

2013-01-01

In this presentation, we investigate concepts and theories for analysing how healthcare professionals achieve overview of patient cases. By 'overview' we mean the situation in which a healthcare professional with sufficient certainty and in concrete situations knows how to proceed based on available information upon a patient. Achieving overview is central for the efficient and safe use of healthcare IT systems, and for the realization of the potential improvements of healthcare that are behind investments in such systems. We focus on the theories of decision-making, sensemaking, narratives, ethnomethodology and distributed cognition. Whereas decision-making theory tend to be sequential and normative, we find the concept of 'functional deployment' in sensemaking theory, 'emplotment' in narrative theory, the focus on 'members' methods' in ethnomethodology and the inclusion of 'computational artifacts' in distributed cognition helpful.

Operational effectiveness and quality assurance mechanisms with stochastic demand of blood supply: blood bank case study.

PubMed

Smith, Alan D

2011-01-01

A general overview of various blood products operational effectiveness and related strategies that can be utilised by service providers (in particular, healthcare providers) is presented in the present study. In terms of the massive volumes of blood products, the North American blood centres collect more than eight million units of whole blood, which represents appropriately 50% of the US and Quebec, Canada?s volunteer donor blood supply. A case study of the quality inspection and inventory control concerns of the Central Blood Bank, located in the metropolitan area of Pittsburgh, PA, is presented. Initially, brief introduction to its general operating environment is followed by sections describing its general situation, quality-service initiatives, and followed by a fairly detailed discussion of the practical applications of lessons learned from the case study.

NEUROBILOGY OF ASPERGER'S SYNDROME : A CASE STUDY AND OVERVIEW

PubMed Central

Duggal, Harpreet S.; Dutta, Siddhartha; Sinha, Vinod K.; Basu, Soumya; Pandey, Smita; Nizamie, Haque S.; Nizamie, Alka

2001-01-01

Asperger's syndrome is an autistic spectrum disorder, which has engendered lesser attention in comparison to autism. Recent literature has focused on the involvement of cortical areas of the brain in this syndrome. We report a case of Asperger′s syndrome in which an extensive work-up, including neuropsychological, neurophysiological and neuroimaging procedures, were undertaken. The findings of the various investigative procedures are discussed and literature supporting the neurobiological basis of Asperger's syndrome is highlighted. Finally, we briefly touch upon the ‘Theory of Mind’ construct in autistic spectrum disorders. PMID:21407867

Overcoming Constraints in Healthcare with Cloud Technology.

PubMed

Hucíková, Anežka; Babic, Ankica

2016-01-01

Transitioning enterprise operations to the cloud brings a variety of opportunities and challenges. Such step requires a deep and complex understanding of all elements related to the technology as well as defining the manner in which specific cloud challenges can be dealt with. To provide a better understanding of these opportunities and challenges within healthcare, systematic literature overview and industrial cases review is used. Results of the two methods show interconnection between cloud deployment advantages and constrains. However, healthcare case studies provide interesting insights emphasizing cloud complexity and superposition which seems to balance organizational limitations.

Impact of Childhood Sexual Abuse on College Student Development: A Seven-Vectors Perspective

ERIC Educational Resources Information Center

Goldberg, Daniel B.

2016-01-01

The application of theory in this article expanded on Chickering and Reisser's ([Chickering, A. W., 1993]) 7-vectors framework by considering the effects of childhood sexual abuse (CSA) on the normal experience of student development in higher education. The article includes an overview of the prevalence and effects of CSA and a case study of a…

Voice/Data Integration in Mobile Radio Networks: Overview and Future Research Directions

DTIC Science & Technology

1989-09-30

degradation in interactive speech when delays are less than about 300 ms (Gold 1977; Gitman and Frank, 1978). When delays are larger (between 300 ms and 1.5...222-267. Gitman , 1. and H. Frank (1978), "Economic Analysis of Integrated Voice and Data Networks: A Case Study," Proc. IEEE 66 1549-1570. Glynn, P.W

More than Kissing Babies? Current Child and Family Policy in the United States.

ERIC Educational Resources Information Center

Jacobs, Francine H., Ed.; Davies, Margery W., Ed.

Meant to orient a broad audience to basic issues of child and family policy in the United States today, this book includes an overview of the recent history of child and family policy in the United States, an exploration of several political economic conditions underlying changes in these policies, case studies of selected local, state and federal…

Using Dynamic Geometry Software GeoGebra in Developing Countries: A Case Study of Impressions of Mathematics Teachers in Nepal

ERIC Educational Resources Information Center

Mainali, Bhesh Raj; Key, Mary Beth

2012-01-01

This article describes a professional development initiative for fifteen mathematics teachers in the use of dynamic geometry software GeoGebra. A four-day introductory workshop was given in Nepal to provide an overview of GeoGebra and its possible integration in the teaching/learning of secondary school mathematics there. Teachers' impressions and…

Construction Material-Based Methodology for Military Contingency Base Construction: Case Study of Dhaka, Bangladesh

DTIC Science & Technology

2016-08-01

of the operational environment to anticipate the impacts that siting and operating CBs will have on the local context, and to consider the effects ...17 Figure 7. Density and effective proximity factor (McNulty 2009b...Area-wise consumption of cement, FY2010 (Nahar 2011). ...............................44 Figure 23. Overview of Bangladesh [green: office, orange

Architecture Analysis with AADL: The Speed Regulation Case-Study

DTIC Science & Technology

2014-11-01

Overview Functional Hazard Analysis ( FHA ) Failures inventory with description, classification, etc. Fault-Tree Analysis (FTA) Dependencies between...University Pittsburgh, PA 15213 Julien Delange Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of...Information Operations and Reports , 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any

"The Sacred Spark of Wonder": Local Museums, Australian Curriculum History, and Pre-Service Primary Teacher Education: A Tasmanian Case Study

ERIC Educational Resources Information Center

Brett, Peter

2014-01-01

This article explores the intersections between museum learning in a distinctive Tasmanian setting, the possibilities of a new national History curriculum, and the evolving views and professional practices of pre-service primary teachers at one Australian university. Following a brief overview of the framework for local and Australian history that…

Re-Purposing an OER for the Online Language Course: A Case Study of "Deutsch Interaktiv" by the Deutsche Welle

ERIC Educational Resources Information Center

Dixon, Edward M.; Hondo, Junko

2014-01-01

This paper will describe pedagogical approaches for re-purposing an open educational resource (OER) designed and produced by the Deutsche Welle. This free online program, "Deutsch Interaktiv," consists of authentic digital videos, slideshows and audio texts and gives a contemporary overview of the culture and language in Germany, Austria…

Operation Slipper: The Australian Defence Force and Private Military Contractors in Afghanistan

DTIC Science & Technology

2015-05-21

methodology adopted for this study. 8 Brown, “Guns for Hire.” 6 Section four presents the case...PMCs.”11 Further, Stanley’s research provides an insight into the use of PMCs from a global perspective using the supply and demand framework. Stanley...seminal work is both historical and global while providing a holistic overview of 11 Stanley

Strategic Planning in Higher Education: A Guide for Heads of Institutions, Senior Managers and Members of Governing Bodies.

ERIC Educational Resources Information Center

Higher Education Funding Council for England, Bristol.

This guide provides examples of good practice in strategic planning within higher education, particularly as it applies to Northern Ireland. Examples are drawn from the experiences of 13 case study universities and colleges. Sections of the report include a summary; an introduction and overview of the strategic planning process; and a discussion…

Resilient Therapy: Strategic Therapeutic Engagement with Children in Crisis

ERIC Educational Resources Information Center

Hart, Angie; Blincow, Derek

2008-01-01

This article offers an overview of Resilient Therapy (RT) and outlines a case study of how it can be used in practice. RT draws on the resilience research base, and has been designed to meet the needs of children in crisis by providing insights and analytical tools that help carers and practitioners build relationships of trust in the hardest of…

Development of tools for evaluating integrated municipal waste management using life-cycle management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thorneloe, S.; Weitz, K.; Nishtala, S.

1998-08-01

Municipal solid waste (MSW) management increasingly is based on integrated systems. The US initiated research in 1994 through funding by the US Environmental Protection Agency and the US Department of Energy to develop (1) a decision support tool; (2) a database; and (3) case studies. This paper provides an overview of the research that is in process.

Nanomagnetism: A Case History of Nanoscience and Technology

ERIC Educational Resources Information Center

Freeman, Mark

2009-01-01

This paper overviews the occurrence and study of magnetism on nanometer-length scales, that is, at sizes where the natural unit on a ruler would be one-billionth of a meter. Nanomagnetism has fascinating early origins on planet Earth, and we must first go back a couple billion years to get to the beginning of the story. Then we will quickly make…

True and False Allegations of Child Sexual Abuse: Assessment and Case Management.

ERIC Educational Resources Information Center

Ney, Tara, Ed.

This book addresses the clinical, legal, and ethical issues arising in child sexual abuse cases; the assessment and case management of allegations; research issues; and practice recommendations. Chapter titles are as follows: "Assessing Allegations in Child Sexual Abuse: An Overview" (Tara Ney); "The Nature of Allegations of Child…

Medical social work practice in child protection in China: A multiple case study in Shanghai hospitals.

PubMed

Zhao, Fang; Hämäläinen, Juha; Chen, Yu-Ting

2017-01-01

With the rapid development of the child welfare system in China over recent years, medical social work has been increasingly involved in providing child protection services in several hospitals in Shanghai. Focusing on five cases in this paper, the exploratory study aims to present a critical overview of current practices and effects of medical social work for child protection, based on a critical analysis of the multidimensional role of social work practitioners engaged in the provision of child protection services as well as potential challenges. Implications and suggestions for future improvements of China's child protection system are also discussed.

Care of the suicidal pediatric patient in the ED: a case study.

PubMed

Schmid, Alexis M; Truog, Amy W; Damian, Frances J

2011-09-01

The suicide rate among children and adolescents has increased worldwide over the past few decades, and many who attempt suicide are first seen at EDs. At Childrens Hospital Boston (CHB), an algorithm-the Risk of Suicidality Clinical Practice Algorithm-has been developed to ensure evidence-based care supported by best practice guidelines. The authors of this article provide an overview of pediatric suicide and suicide attempts; describe screening, assessment, and interventions used at CHB; and discuss the nursing implications. An illustrative case study is also provided. algorithm, Asperger's syndrome, attempted suicide, bullying, emergency, emergency department, patient safety, pediatrics, pediatric suicide, suicide, suicide screening, triage.

Current Practices in Constructing and Evaluating Assurance Cases With Applications to Aviation

NASA Technical Reports Server (NTRS)

Rinehart, David J.; Knight, John C.; Rowanhill, Jonathan

2015-01-01

This report introduces and provides an overview of assurance cases including theory, practice, and evaluation. This report includes a section that introduces the principles, terminology, and history of assurance cases. The core of the report presents twelve example uses of assurance cases from a range of domains, using a novel classification scheme. The report also reviews the state of the art in assurance case evaluation methods.

Contaminated drinking water and rural health perspectives in Rajasthan, India: an overview of recent case studies.

PubMed

Suthar, Surindra

2011-02-01

Access to safe drinking water is an important issue of health and development at national, regional, and local levels. The concept of safe drinking water assumes greater significance in countries like India where the majority of the population lives in villages with bare infrastructures and poor sanitation facilities. This review presents an overview of drinking water quality in rural habitations of northern Rajasthan, India. Although fluoride is an endemic problem to the groundwater of this region, recently, other anthropogenic chemicals has also been reported in the local groundwater. Recent case studies indicate that about 95% of sites of this region contain a higher fluoride level in groundwater than the maximum permissible limit as decided by the Bureau of Indian Standards. Nitrate (as NO3-) contamination has appeared as another anthropogenic threat to some intensively cultivable rural habitations of this region. Biological contamination has appeared as another issue of unsafe drinking water resources in rural areas of the state. Recent studies have claimed a wide variety of pathogenic bacteria including members of the family Enterobacteriaceae in local drinking water resources. Overall, the quality of drinking water in this area is not up to the safe level, and much work is still required to establish a safe drinking water supply program in this area.

Informal Caregiving for Cancer Patients

PubMed Central

Romito, Francesca; Goldzweig, Gil; Cormio, Claudia; Hagedoorn, Mariët; Andersen, Barbara L.

2013-01-01

According to the recent worldwide estimation by the GLOBOCAN project, in total, 12.7 million new cancer cases and 7.6 million cancer deaths occurred in 2008. The worldwide number of cancer survivors within 5 years of diagnosis has been estimated at be almost 28.8 million. Informal caregivers, such as family members and close friends, provide essential support to cancer patients. The authors of this report provide an overview of issues in the study of informal caregivers for cancer patients and long-term survivors in the United States and Europe, characterizing the caregivers commonly studied; the resources currently available to them; and their unmet needs, their psychosocial outcomes, and the psychosocial interventions tailored to their special circumstances. A broad overview of the state of research and knowledge, both in Europe and the United States, and observations on the directions for future research are provided. PMID:23695928

Litigation and Students with Disabilities: An Overview of Cases From 2015

ERIC Educational Resources Information Center

Katsiyannis, Antonis; Counts, Jennifer; Popham, Michelle; Ryan, Joseph; Butzer, Madeline

2016-01-01

Special education is the most highly litigated area within the field of education. Therefore, the purpose of the current article is to highlight cases (court decisions, Office of Civil Rights rulings, and State Educational Agency hearings) involving students with disabilities in 2015. Highlights from the case law point to the need for school…

Getting Down to Business: What's It All About? Module 1. [Student Guide]. Entrepreneurship Training Components.

ERIC Educational Resources Information Center

McFarlane, Carolyn

This module, first of a series of 36, contains a general overview of small business ownership and what it involves. In the first unit, the student is presented with a case study. This is followed by a definition of small business, kinds of small businesses, life as a small business owner, and personal qualities that small business owners should…

Steps to Developing the New Orleans Strategic Energy Plan (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, E.

2011-01-01

This presentation was given by NREL's Elizabeth Doris (Brown) to the New Orleans City Council in January 2008. NREL was funded by DOE to provide technical assistance to New Orleans after Hurricanes Katrina and Rita. The presentation provides an overview of strategic energy planning, case studies, and suggested next steps for implementing energy efficiency and renewable energy into the city's rebuilding efforts.

Overview of Epidemiology, Genetics, Birth Defects, and Chromosome Abnormalities Associated With CDH

PubMed Central

Pober, Barbara R.

2010-01-01

Congenital diaphragmatic hernia (CDH) is a common and well-studied birth defect. The etiology of most cases remains unknown but increasing evidence points to genetic causation. The data supporting genetic etiologies which are detailed below include the association of CDH with recurring chromosome abnormalities, the existence of CDH-multiplex families, and the co-occurrence of CDH with additional congenital malformations. PMID:17436298

A Three-Dimensional Approach and Open Source Structure for the Design and Experimentation of Teaching-Learning Sequences: The Case of Friction

ERIC Educational Resources Information Center

Besson, Ugo; Borghi, Lidia; De Ambrosis, Anna; Mascheretti, Paolo

2010-01-01

We have developed a teaching-learning sequence (TLS) on friction based on a preliminary study involving three dimensions: an analysis of didactic research on the topic, an overview of usual approaches, and a critical analysis of the subject, considered also in its historical development. We found that mostly the usual presentations do not take…

A consumer`s guide to lattice QCD results

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeGrand, T.

1994-12-01

The author presents an overview of recent lattice QCD results on hadron spectroscopy and matrix elements. Case studies include light quark spectroscopy, the determination of {alpha}{sub s} from heavy quark spectroscopy, the D-meson decay constant, a calculation of the Isgur-Wise function, and some examples of the (lack of) effect of sea quarks on matrix elements. The review is intended for the nonexpert.

The Collective Impact Model and Its Potential for Health Promotion: Overview and Case Study of a Healthy Retail Initiative in San Francisco

ERIC Educational Resources Information Center

Flood, Johnna; Minkler, Meredith; Lavery, Susana Hennessey; Estrada, Jessica; Falbe, Jennifer

2015-01-01

As resources for health promotion become more constricted, it is increasingly important to collaborate across sectors, including the private sector. Although many excellent models for cross-sector collaboration have shown promise in the health field, collective impact (CI), an emerging model for creating larger scale change, has yet to receive…

Design and implementation of observational studies to measure disease burden with a focus on stroke.

PubMed

Howard, George; Howard, Virginia J

2018-02-01

Observational epidemiological studies have the dual goals of measuring disease burden and assessing the association between exposures and outcomes. This report focuses on the first of these goals and provides an overview of design considerations of commonly used approaches, specifically community surveillance studies, cross-sectional studies, and longitudinal cohort studies. Each of these designs has strengths and weaknesses, with no study design being superior in all cases. Rather, these designs are complementary to achieve a better understanding of the burden of stroke.

Safety analysis in test facility design

NASA Astrophysics Data System (ADS)

Valk, A.; Jonker, R. J.

1990-09-01

The application of safety analysis techniques as developed in, for example nuclear and petrochemical industry, can be very beneficial in coping with the increasing complexity of modern test facility installations and their operations. To illustrate the various techniques available and their phasing in a project, an overview of the most commonly used techniques is presented. Two case studies are described: the hazard and operability study techniques and safety zoning in relation to the possible presence of asphyxiating atmospheres.

The 'Amistad' Case. Lesson Plan.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

Teaching about the Amistad case provides correlations to the National Standards for History, and Civics and Government. An overview of the events of 1839 is given in this lesson plan. Seven student activities include reading and using primary source documents, writing journal articles, viewing the movie "Amistad," and giving…

Making intelligent systems team players: Additional case studies

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Schreckenghost, Debra L.; Rhoads, Ron W.

1993-01-01

Observations from a case study of intelligent systems are reported as part of a multi-year interdisciplinary effort to provide guidance and assistance for designers of intelligent systems and their user interfaces. A series of studies were conducted to investigate issues in designing intelligent fault management systems in aerospace applications for effective human-computer interaction. The results of the initial study are documented in two NASA technical memoranda: TM 104738 Making Intelligent Systems Team Players: Case Studies and Design Issues, Volumes 1 and 2; and TM 104751, Making Intelligent Systems Team Players: Overview for Designers. The objective of this additional study was to broaden the investigation of human-computer interaction design issues beyond the focus on monitoring and fault detection in the initial study. The results of this second study are documented which is intended as a supplement to the original design guidance documents. These results should be of interest to designers of intelligent systems for use in real-time operations, and to researchers in the areas of human-computer interaction and artificial intelligence.

Benefits and challenges of a QSP approach through case study: Evaluation of a hypothetical GLP-1/GIP dual agonist therapy.

PubMed

Rieger, Theodore R; Musante, Cynthia J

2016-10-30

Quantitative Systems Pharmacology (QSP) is an emerging science with increasing application to pharmaceutical research and development paradigms. Through case study we provide an overview of the benefits and challenges of applying QSP approaches to inform program decisions in the early stages of drug discovery and development. Specifically, we describe the use of a type 2 diabetes systems model to inform a No-Go decision prior to lead development for a potential GLP-1/GIP dual agonist program, enabling prioritization of exploratory programs with higher probability of clinical success. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Energy Sources and Systems Analysis: 40 South Lincoln Redevelopment District (Short Report)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2011-08-01

This report presents the a brief overview of the results of a case study to analyze district energy systems for their potential use in a project that involves redeveloping 270 units of existing public housing, along with other nearby sites. When complete, the redevelopment project will encompass more than 900 mixed-income residential units, commercial and retail properties, and open space. The analysis estimated the hourly heating, cooling, domestic hot water, and electric loads required by the community; investigated potential district system technologies to meet those needs; and researched available fuel sources to power such systems. A full report of thismore » case study is also available.« less

Developing a health information network within an integrated delivery system: a case study.

PubMed

Wager, K A; Heda, S; Austin, C J

1997-05-01

Changes in the health care environment, such as the growth of integrated delivery systems and the proliferation of managed care, are having a profound impact on the way in which health care organizations manage both clinical and financial information. Health information networks (HINs) are emerging to support the goals and internal needs of integrated delivery systems. In this environment, health care managers must assume a leadership role in planning for the development of HINs. The article provides an overview of the principal issues that should be addressed in an organization's information systems plan when a HIN is being developed and includes a case study that illustrates the key points discussed.

[Diphenhydramine addiction and detoxification. A systematic review and case report].

PubMed

Erbe, Sebastian; Bschor, Tom

2013-07-01

In many countries diphenhydramine (DPH) is commonly available over the counter, frequently used, and generally regarded as a harmless drug. It is used as a sedative, antiallergic or antiemetic substance. We present a systematic review of literature search in Pubmed from 1972 to 2012 describing DPH addiction. The literature search in reveals that the addictive potential of DPH can be regarded as proved, based on cases series, eight case reports, a pharmacological overview, one uncontrolled, and one randomized, placebo controlled study. In addition we report a case of an abstinent alcoholic patient treated in our department for DPH-dependency. Especially when treating patients with a history of addiction, physicians should consider and check the possibility of a DPH dependency. © Georg Thieme Verlag KG Stuttgart · New York.

Essentials of Enrollment Management: Cases in the Field

ERIC Educational Resources Information Center

Black, Jim

2004-01-01

In AACRAO's new publication Essentials of Enrollment Management: Cases in the Field experts in enrollment management representing all types of institutions reveal the evolution of the enrollment strategies implemented at their institutions, the results, and the lessons learned. The introductory chapter provides an overview of themes and models…

20 CFR 655.1300 - Overview of subpart B and definition of terms.

Code of Federal Regulations, 2010 CFR

2010-04-01

... a case-by-case basis. Such designations must be based on information provided by State agencies or... employee. Occupational Safety and Health Administration (OSHA) means the organizational component of the... Foreign Labor Certification (OFLC) means the organizational component of the ETA that provides national...

[Disciplinary verdicts in cases of child abuse; lessons for paediatricians].

PubMed

Berkers, Gitte; Biesaart, Monique C I H; Leeuwenburgh-Pronk, Wendela G

2015-01-01

To give an overview of disciplinary cases regarding action taken by paediatricians and paediatric residents in cases of (suspected) child abuse and to discuss the considerations of the disciplinary board in these cases. Retrospective, descriptive study. We considered all disciplinary cases instigated from 2001 to 2013 against paediatricians or paediatric residents and selected complaints regarding action taken in cases of (suspected) child abuse. We divided these complaints into six categories and studied the considerations of the disciplinary board in these cases. From 33 disciplinary cases instigated from 2001 to 2013, we selected 76 complaints regarding action taken by paediatricians or paediatric residents in cases of (suspected) child abuse. The majority of these complaints concerned the reporting or requesting of information in the context of (suspected) child abuse. All of the complaints in the category 'unwarranted reporting of child abuse' were declared unfounded by the disciplinary judge. The disciplinary board declared all complaints unfounded in cases where the paediatrician or paediatric resident had followed the Dutch national protocol regarding reporting of child abuse and domestic violence. The disciplinary board examines whether action was taken in accordance with reasonable standards of professional competence and considers that paediatricians have an important role in identifying child abuse.

Overview of MSFC AMSD Integrated Modeling and Analysis

NASA Technical Reports Server (NTRS)

Cummings, Ramona; Russell, Kevin (Technical Monitor)

2002-01-01

Structural, thermal, dynamic, and optical models of the NGST AMSD mirror assemblies are being finalized and integrated for predicting cryogenic vacuum test performance of the developing designs. Analyzers in use by the MSFC Modeling and Analysis Team are identified, with overview of approach to integrate simulated effects. Guidelines to verify the individual models and calibration cases for comparison with the vendors' analyses are presented. In addition, baseline and proposed additional scenarios for the cryogenic vacuum testing are briefly described.

A Descriptive Analysis of Overviews of Reviews Published between 2000 and 2011

PubMed Central

Hartling, Lisa; Chisholm, Annabritt; Thomson, Denise; Dryden, Donna M.

2012-01-01

Background Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis. Objectives To describe the methodological approaches in overviews of interventions. Design Descriptive study. Methods We searched 4 databases from 2000 to July 2011; we handsearched Evidence-based Child Health: A Cochrane Review Journal. We defined an overview as a study that: stated a clear objective; examined an intervention; used explicit methods to identify SRs; collected and synthesized outcome data from the SRs; and intended to include only SRs. We did not restrict inclusion by population characteristics (e.g., adult or children only). Two researchers independently screened studies and applied eligibility criteria. One researcher extracted data with verification by a second. We conducted a descriptive analysis. Results From 2,245 citations, 75 overviews were included. The number of overviews increased from 1 in 2000 to 14 in 2010. The interventions were pharmacological (n = 20, 26.7%), non-pharmacological (n = 26, 34.7%), or both (n = 29, 38.7%). Inclusion criteria were clearly stated in 65 overviews. Thirty-three (44%) overviews searched at least 2 databases. The majority reported the years and databases searched (n = 46, 61%), and provided key words (n = 58, 77%). Thirty-nine (52%) overviews included Cochrane SRs only. Two reviewers independently screened and completed full text review in 29 overviews (39%). Methods of data extraction were reported in 45 (60%). Information on quality of individual studies was extracted from the original SRs in 27 (36%) overviews. Quality assessment of the SRs was performed in 28 (37%) overviews; at least 9 different tools were used. Quality of the body of evidence was assessed in 13 (17%) overviews. Most overviews provided a narrative or descriptive analysis of the included SRs. One overview conducted indirect analyses and the other conducted mixed treatment comparisons. Publication bias was discussed in 18 (24%) overviews. Conclusions This study shows considerable variation in the methods used for overviews. There is a need for methodological rigor and consistency in overviews, as well as empirical evidence to support the methods employed. PMID:23166744

A descriptive analysis of overviews of reviews published between 2000 and 2011.

PubMed

Hartling, Lisa; Chisholm, Annabritt; Thomson, Denise; Dryden, Donna M

2012-01-01

Overviews of systematic reviews compile data from multiple systematic reviews (SRs) and are a new method of evidence synthesis. To describe the methodological approaches in overviews of interventions. Descriptive study. We searched 4 databases from 2000 to July 2011; we handsearched Evidence-based Child Health: A Cochrane Review Journal. We defined an overview as a study that: stated a clear objective; examined an intervention; used explicit methods to identify SRs; collected and synthesized outcome data from the SRs; and intended to include only SRs. We did not restrict inclusion by population characteristics (e.g., adult or children only). Two researchers independently screened studies and applied eligibility criteria. One researcher extracted data with verification by a second. We conducted a descriptive analysis. From 2,245 citations, 75 overviews were included. The number of overviews increased from 1 in 2000 to 14 in 2010. The interventions were pharmacological (n = 20, 26.7%), non-pharmacological (n = 26, 34.7%), or both (n = 29, 38.7%). Inclusion criteria were clearly stated in 65 overviews. Thirty-three (44%) overviews searched at least 2 databases. The majority reported the years and databases searched (n = 46, 61%), and provided key words (n = 58, 77%). Thirty-nine (52%) overviews included Cochrane SRs only. Two reviewers independently screened and completed full text review in 29 overviews (39%). Methods of data extraction were reported in 45 (60%). Information on quality of individual studies was extracted from the original SRs in 27 (36%) overviews. Quality assessment of the SRs was performed in 28 (37%) overviews; at least 9 different tools were used. Quality of the body of evidence was assessed in 13 (17%) overviews. Most overviews provided a narrative or descriptive analysis of the included SRs. One overview conducted indirect analyses and the other conducted mixed treatment comparisons. Publication bias was discussed in 18 (24%) overviews. This study shows considerable variation in the methods used for overviews. There is a need for methodological rigor and consistency in overviews, as well as empirical evidence to support the methods employed.

Proceedings of the Second Workshop on Numerical Analysis of Human and Surrogate Response to Accelerative Loading

DTIC Science & Technology

2018-02-01

Dissection  2 primary experimental loading cases Tissue-Level Characterization Quasi -Static Bending (Hueur et al., 2006) High-Rate Combined...Yang Hybrid III Crash-Dummy Lower Ext. under High Speed Vertical Loading: A Combined Experimental and Computational Study Wayne State 14:05...25 Tusit Weerasooriya Mechanical Response of Human and Animal Bones: Overview of ARL Experimental Research ARL 11:50 Wayne Chen

West Meets East in Central Asia: Competing Discourses on Secondary Education Reform in the Kyrgyz Republic.

ERIC Educational Resources Information Center

De Young, Alan J.

The Kyrgyz Republic--a remote mountainous region--is one of five former Soviet states in central Asia. This case study begins with a brief overview of the political and economic situation of the Kyrgyz Republic and its relation to aims of Soviet schooling in the 20th century. A critique of the Soviet schooling model by foreign academics before and…

Federal Litigation Arising from Personnel Practices of Southern School Boards from 1970 through 1981 in the Fifth Circuit Court of Appeals Area.

ERIC Educational Resources Information Center

Sistrunk, Walter E.; Guin, Mary Linda

This paper offers administrators, teachers, and school boards an introduction to legal issues surrounding teacher dismissal and school desegregation and summarizes a study of all teacher dismissal cases heard from 1970 through 1981 in the Fifth Circuit Court of Appeals. Most of the report is devoted to an overview of the historical development of…

Chinese Students' Attitudes Towards the Use of English-Medium Instruction into the Curriculum Courses: A Case Study of a National Key University in Beijing

ERIC Educational Resources Information Center

Muthanna, Abdulghani; Miao, Pei

2015-01-01

This article outlines the necessity for investigating the attitudes of local students towards the use of the English-medium instruction (EMI) strategy in their programs in China. It starts by presenting an overview of English as a global language, how English is emphasized in China, and briefly presents the concept of "Attitude" and how…

Are We Asking the Right Questions? Moving beyond the State vs Non-State Providers Debate: Reflections and a Case Study from India

ERIC Educational Resources Information Center

Bangay, Colin; Latham, Michael

2013-01-01

This paper provides an overview of recent trends in basic education provision in India: charting an impressive expansion of enrolment in public schools but a growing concern with the quality of learning. Concerns around quality are seen as a driving factor in the migration of students from the public sector to low fee private schools. While there…

Can We Get National Labour Market Information into the Classroom Faster? The Information Technology Professional Program. An Association of Canadian Community Colleges Sponsored Sectoral Case Study.

ERIC Educational Resources Information Center

Diakun, Denyce; Phillips, Rodger

The Software Human Resource Council (SHRC) is a nonprofit sectoral council that speaks for software professionals throughout the Canadian economy. The SHRC's mission is to increase the number of Information Technology (IT) workers in Canada. This paper gives a brief overview of the evolution of SHRC's Information Technology Professional Program…

Defense Advanced Research Projects Agency: Key Factors Drive Transition of Technologies, but Better Training and Data Dissemination Can Increase Success

DTIC Science & Technology

2015-11-01

more detail. Table 1: Overview of DARPA Programs Selected for GAO Case Study Analyses Program name Program description Advanced Wireless Networks ...Selected DARPA Programs Program name According to DARPA portfolio-level database According to GAO analysis Advanced Wireless Networks for the Soldier...with potential transition partners Achievement of clearly defined technical goals Successful transition Advanced Wireless Networks for Soldier

Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (PME 20) (20th, Valencia, Spain, July 8-12, 1996). Volume 4.

ERIC Educational Resources Information Center

Puig, Luis, Ed.; Gutierrez, Angel, Ed.

The fourth volume of this proceedings contains full research articles. Papers include: (1) "Conceptual and procedural approaches to problem-solving" (Y. Mohammad-Yusof and D. Tall); (2)"Teaching differential equations to chemistry and biology students: An overview on methodology of qualitative research. A case study" (M. Moreno and C. Azcarate);…

Evolving 50–50% bilingual pedagogy in Alberta: what does the research say?

PubMed Central

Naqvi, Rahat; Schmidt, Elaine; Krickhan, Marlene

2014-01-01

This paper outlines the provincial frameworks that define the Spanish bilingual program in Alberta, Canada, provides an historical overview of its pedagogic constraints and evolution, and proposes a framework for bilingual pedagogy. The framework is conceptualized from the research evidence of three local case studies, and is based on the centrality of cross-linguistic transfer, in relation to linguistic interdependence and bilingual learning. PMID:24987378

Mechanisms of ear trauma and reconstructive techniques in 105 consecutive patients.

PubMed

Kolodzynski, Michail N; Kon, Moshe; Egger, Silvan; Breugem, Corstiaan C

2017-02-01

Acquired auricular deformities may diminish facial esthetics and cause psychological distress. The aim of this article is to provide an overview of the type of injuries and applied reconstructive techniques in a large academic hospital in The Netherlands. A retrospective chart review was conducted for the last 105 patients who underwent auricular reconstruction for an acquired deformity. Data concerning gender, affected side, cause of injury, anatomical region, the previous and further surgeries, type of cartilage, and skin cover used were collected and analyzed. 105 patients were included. Acquired auricular deformities were mainly caused by bite injuries (22 %), traffic accidents (17 %), burns (9.5 %), and post-otoplasty complications (9.5 %). The upper third of the auricle was most often injured (41 %), followed by the entire auricle (19 %). 70 % of cases required reconstruction with costal cartilage. The most common form of cutaneous cover was a postauricular skin flap (40 % of cases). This study gives a complete overview of causes and treatment of acquired auricular deformities. The results are comparable with the results of similar studies found in literature. Bite wounds are the leading cause of acquired auricular injuries. The upper third is most commonly affected. In the largest percentage of reconstructions, costal cartilage and a postauricular flap were used to correct the deformity.

Legal issues in governing genetic biobanks: the Italian framework as a case study for the implications for citizen's health through public-private initiatives.

PubMed

Piciocchi, Cinzia; Ducato, Rossana; Martinelli, Lucia; Perra, Silvia; Tomasi, Marta; Zuddas, Carla; Mascalzoni, Deborah

2018-04-01

This paper outlines some of the challenges faced by regulation of genetic biobanking, using case studies coming from the Italian legal system. The governance of genetic resources in the context of genetic biobanks in Italy is discussed, as an example of the stratification of different inputs and rules: EU law, national law, orders made by authorities and soft law, which need to be integrated with ethical principles, technological strategies and solutions. After providing an overview of the Italian legal regulation of genetic data processing, it considers the fate of genetic material and IP rights in the event of a biobank's insolvency. To this end, it analyses two case studies: a controversial bankruptcy case which occurred in Sardinia, one of the first examples of private and public partnership biobanks. Another case study considered is the Chris project: an example of partnership between a research institute in Bolzano and the South Tyrolean Health System. Both cases seem to point in the same direction, suggesting expediency of promoting and improving public-private partnerships to manage biological tissues and biotrust to conciliate patent law and public interest.

Epidemiological profile of cutaneous leishmaniasis in Morocco, 2004-2013.

PubMed

Laboudi, M

2017-02-01

The main objective of our study is to provide a comprehensive overview of the situation of cutaneous leishmaniasis in Morocco. We therefore conducted a retrospective descriptive study covering the decade 2004-2013. Data were collected from the Moroccan Ministry of Health's annual reports about the national program against leishmaniasis. These data show a regression in the cases due to Leishmania major and the persistence of L. tropica transmission. Mapping cutaneous leishmaniasis cases reported between 2004 and 2013 showed geographical changes ; the number of cases due to L. tropica were concentrated in the regions of Marrakech-Tensift-Elhaouz, Souss Massa-Draa Tadla-Azila, and Taza-Al Hoceima-Taounate. Cutaneous disease due to L. major was most common in the Souss-Massa-Draa region. Continuous monitoring of the epidemiological situation is important to assess the actions taken to reduce its incidence.

Spatial distribution of structural defects in Cz-seeded directionally solidified silicon ingots: An etch pit study

NASA Astrophysics Data System (ADS)

Lantreibecq, A.; Legros, M.; Plassat, N.; Monchoux, J. P.; Pihan, E.

2018-02-01

The PV properties of wafers processed from Cz-seeded directionally solidified silicon ingots suffer from variable structural defects. In this study, we draw an overview on the types of structural defects encountered in the specific case of full 〈1 0 0〉 oriented growth. We found micro twins, background dislocations, and subgrains boundaries. We discuss the possible links between thermomechanical stresses and growth processes with spatial evolution of both background dislocation densities and subgrain boundaries length.

Reducing the number of laboratory animals used in tissue engineering research by restricting the variety of animal models. Articular cartilage tissue engineering as a case study.

PubMed

de Vries, Rob B M; Buma, Pieter; Leenaars, Marlies; Ritskes-Hoitinga, Merel; Gordijn, Bert

2012-12-01

The use of laboratory animals in tissue engineering research is an important underexposed ethical issue. Several ethical questions may be raised about this use of animals. This article focuses on the possibilities of reducing the number of animals used. Given that there is considerable debate about the adequacy of the current animal models in tissue engineering research, we investigate whether it is possible to reduce the number of laboratory animals by selecting and using only those models that have greatest predictive value for future clinical application of the tissue engineered product. The field of articular cartilage tissue engineering is used as a case study. Based on a study of the scientific literature and interviews with leading experts in the field, an overview is provided of the animal models used and the advantages and disadvantages of each model, particularly in terms of extrapolation to the human situation. Starting from this overview, it is shown that, by skipping the small models and using only one large preclinical model, it is indeed possible to restrict the number of animal models, thereby reducing the number of laboratory animals used. Moreover, it is argued that the selection of animal models should become more evidence based and that researchers should seize more opportunities to choose or create characteristics in the animal models that increase their predictive value.

The contribution of case study design to supporting research on Clubhouse psychosocial rehabilitation.

PubMed

Raeburn, Toby; Schmied, Virginia; Hungerford, Catherine; Cleary, Michelle

2015-10-01

Psychosocial Clubhouses provide recovery-focused psychosocial rehabilitation to people with serious mental illness at over 300 sites in more than 30 countries worldwide. To deliver the services involved, Clubhouses employ a complex mix of theory, programs and relationships, with this complexity presenting a number of challenges to those undertaking Clubhouse research. This paper provides an overview of the usefulness of case study designs for Clubhouse researchers; and suggests ways in which the evaluation of Clubhouse models can be facilitated. The paper begins by providing a brief explanation of the Clubhouse model of psychosocial rehabilitation, and the need for ongoing evaluation of the services delivered. This explanation is followed by an introduction to case study design, with consideration given to the way in which case studies have been used in past Clubhouse research. It is posited that case study design provides a methodological framework that supports the analysis of either quantitative, qualitative or a mixture of both types of data to investigate complex phenomena in their everyday contexts, and thereby support the development of theory. As such, case study approaches to research are well suited to the Clubhouse environment. The paper concludes with recommendations for future Clubhouse researchers who choose to employ a case study design. While the quality of case study research that explores Clubhouses has been variable in the past, if applied in a diligent manner, case study design has a valuable contribution to make in future Clubhouse research.

Critically appraising qualitative research: a guide for clinicians more familiar with quantitative techniques.

PubMed

Kisely, Stephen; Kendall, Elizabeth

2011-08-01

Papers using qualitative methods are increasingly common in psychiatric journals. This overview is an introduction to critically appraising a qualitative paper for clinicians who are more familiar with quantitative methods. Qualitative research uses data from interviews (semi-structured or unstructured), focus groups, observations or written materials. Data analysis is inductive, allowing meaning to emerge from the data, rather than the more deductive, hypothesis centred approach of quantitative research. This overview compares and contrasts quantitative and qualitative research methods. Quantitative concepts such as reliability, validity, statistical power, bias and generalisability have qualitative equivalents. These include triangulation, trustworthiness, saturation, reflexivity and applicability. Reflexivity also shares features of transference. Qualitative approaches include: ethnography, action-assessment, grounded theory, case studies and mixed methods. Qualitative research can complement quantitative approaches. An understanding of both is useful in critically appraising the psychiatric literature.

Space Shuttle Reusable Solid Rocket Motor Program Overview and Lessons Learned

NASA Technical Reports Server (NTRS)

Graves, Stan R.; McCool, Alex (Technical Monitor)

2001-01-01

An overview of the Space Shuttle Reusable Solid Rocket Motor (RSRM) program is provided with a summary of lessons learned since the first test firing in 1977. Fifteen different lessons learned are discussed that fundamentally changed the motor's design, processing, and RSRM program risk management systems. The evolution of the rocket motor design is presented including the baseline or High Performance Solid Rocket Motor (HPM), the Filament Wound Case (FWC), the RSRM, and the proposed Five-Segment Booster (FSB).

Poppers retinopathy

PubMed Central

Luis, Joshua; Virdi, Meena; Nabili, Shahriar

2016-01-01

We present a case of a 52-year-old man with sudden, bilateral central loss of vision as a result of inhalation of ‘poppers’. He was found to have characteristic changes on optical coherence tomography. With conservative treatment, the patient's vision improved marginally at 3 months follow-up. An overview of previous published cases is also included. PMID:26952176

The interface of legal and esthetic considerations

Treesearch

Richard C. Smardon

1979-01-01

This paper is an overview of development of legal/policy factors affecting visual resource management. Review of major legal issues, court cases, laws and administrative decisionmaking reveals that the "action" regarding legal and aesthetic issues is currently in the public arena as managed by administrative agencies. Analysis of key court cases reveals that...

Enhancing Systems Engineering Education Through Case Study Writing

NASA Technical Reports Server (NTRS)

Stevens, Jennifer Stenger

2016-01-01

Developing and refining methods for teaching systems engineering is part of Systems Engineering grand challenges and agenda for research in the SE research community. Retention of systems engineering knowledge is a growing concern in the United States as the baby boom generation continues to retire and the faster pace of technology development does not allow for younger generations to gain experiential knowledge through years of practice. Government agencies, including the National Aeronautics and Space Administration (NASA), develop their own curricula and SE leadership development programs to "grow their own" systems engineers. Marshall Space Flight Center (MSFC) conducts its own Center-focused Marshall Systems Engineering Leadership Development Program (MSELDP), a competitive program consisting of coursework, a guest lecture series, and a rotational assignment into an unfamiliar organization engaged in systems engineering. Independently, MSFC developed two courses to address knowledge retention and sharing concerns: Real World Marshall Mission Success course and its Case Study Writers Workshop and Writers Experience. Teaching case study writing and leading students through a hands-on experience at writing a case study on an SE topic can enhance SE training and has the potential to accelerate the transfer of experiential knowledge. This paper is an overview of the pilot experiences with teaching case study writing, its application in case study-based learning, and identifies potential areas of research and application for case study writing in systems engineering education.

Overview of pertussis: focus on epidemiology, sources of infection, and long term protection after infant vaccination.

PubMed

Edwards, Kathryn M

2005-06-01

Pertussis, or whooping cough, is a bacterial disease characterized by paroxysmal cough often accompanied by inspiratory whoop and posttussive emesis. Although the introduction of whole-cell pertussis vaccine in the 1940s led to a significant decline in the incidence of pertussis, there has been a gradual increase in reported pertussis cases since 1980. Some of these cases are in infants too young to have received routine pertussis vaccination, and many are in adolescents immunized previously as young children. Based on a literature review, an overview of pertussis is provided, focusing on epidemiology, sources of infection, and trends in incidence patterns, particularly among adolescents. Issues surrounding long-term protection after infant vaccination are also discussed. The most dramatic increase in pertussis incidence has been among adolescents and young adults. Waning vaccine-induced immunity and refinements in the diagnosis of pertussis have contributed to the rise in the occurrence of pertussis in older age groups. Disease rates in infants have also increased. Determining the source of infection in infants can be challenging, but studies have demonstrated that many infant cases are attributable to infections in adolescent or adult family members. Pertussis is on the rise, particularly in adolescents. Booster vaccination of adolescents with less-reactogenic acellular pertussis vaccines appears to be the most logical approach to disease prevention in adolescents and reduced transmission to young infants.

Myiasis in humans: an overview and a report of two cases in the Republic of Panama.

PubMed

Powers, N R; Yorgensen, M L; Rumm, P D; Souffront, W

1996-08-01

This paper on myiasis provides varied references from documented sources as an overall review. A review of two case studies, a primary screwworm (cochliomyia hominivorax) infestation and a human botfly (Dermatobia hominis) infestation, as well as information on approaches to positive intervention and remediation are presented. Human myiasis found in the subtropical and tropical regions of the world is a health threat. As a result of the military's expanding role in medical support to various regions where myiasis is endemic, this paper serves to familiarize health care providers with this condition and to provide guidance when dealing with patients affected by myiasis.

Life Cycle Cost Management, Methodology, and Case Studies

DTIC Science & Technology

1977-10-01

PAGES60 14. MONITORING AGENCY NAME G ADORESS(If different from Controlling Office) IS. SECURITY CLASS. (of this report) UNCLASSIFIED 150. DECLASSI FI...DISTRIBUTION STATEMENT (of thA abstract entered In Block 20, It different from Report) I8. SUPPLEMEINTARY NOTES ,.,IOUNCEI 0 Uy...... ....... 1. KEY WORDS...to provide the reader with an overview of the guidelines content and a preview of CAIG O&S costing method - ology .:,idelines. The RzMD report on LCC

A Large-Telescope Natural Guide Star AO System

NASA Technical Reports Server (NTRS)

Redding, David; Milman, Mark; Needels, Laura

1994-01-01

None given. From overview and conclusion:Keck Telescope case study. Objectives-low cost, good sky coverage. Approach--natural guide star at 0.8um, correcting at 2.2um.Concl- Good performance is possible for Keck with natural guide star AO system (SR>0.2 to mag 17+).AO-optimized CCD should b every effective. Optimizing td is very effective.Spatial Coadding is not effective except perhaps at extreme low light levels.

A superconducting quenchgun for delivering lunar derived oxygen to lunar orbit

NASA Technical Reports Server (NTRS)

Nottke, Nathan; Bilby, Curt R.

1990-01-01

The development of a parametric model for a superconducting quenchgun for launching lunar derived liquid oxygen to lunar orbit is detailed. An overview is presented of the quenchgun geometry and operating principles, a definition of the required support systems, and the methods used to size the quenchgun launcher and support systems. An analysis assessing the impact of a lunar quenchgun on the OEXP Lunar Evolution Case Study is included.

Vocational Training and Innovative Practices in the Environmental Sector: A Comparison of Ten EU [European Union] Member States with Specimen Cases. Synthesis Report in the Context of the "Observing Innovations in Vocational Training" Project. CEDEFOP Panorama.

ERIC Educational Resources Information Center

Loos, Roland

This report provides specialist information and application-oriented recommendations to implement innovative environmental vocational education and training (VET) measures and practices. Chapter 1 explains study method and structure. Chapter 2 provides an overview of the current state of environmental VET in Austria, Denmark, Finland, Germany,…

Wilderness - between the promise of hell and paradise: A cultural-historical exploration of a Dutch National Park

Treesearch

Koen Arts; Anke Fischer; Rene van der Wal

2011-01-01

‘Wilderness' is often seen as an ideal state in contemporary debates on ecological restoration. This paper asks what is left of ‘wilderness' in present-day Western Europe and explores this question by drawing on a case study of the Hoge Veluwe National Park in the Netherlands. An overview of intellectual histories of wilderness ideas is used as a backdrop to...

Terminology of the tonsils.

PubMed

Casteleyn, C; Simoens, P; Van den Broeck, W

2011-06-01

Many terms used for referring to tonsillar structures are applied in immunological research. However, in many cases, the use of these terms is not in compliance with official veterinary anatomical nomenclature. This is partly attributable to ambiguous descriptions present in conventional anatomical textbooks. This study gives an overview of pertaining controversial terms and promotes the official anatomical terminology applicable to the tonsils, to enhance the unequivocal transfer of knowledge generated during immunological research. © 2011 Blackwell Verlag GmbH.

Case Study of American Healthways' Diabetes Disease Management Program

PubMed Central

Pope, James E.; Hudson, Laurel R.; Orr, Patty M.

2005-01-01

Disease management has been defined as a system of coordinated health care interventions and communications for populations with conditions in which patient self-care efforts are significant (Disease Management Association of America, 2005). The purpose of this article is to provide an overview of the diabetes disease management program offered by American Healthways (AMHC) and highlight recently reported results of this program (Villagra, 2004a; Espinet et al., 2005). PMID:17288077

A Case Study of Internet Protocol Telephony (IPT) Implementation at United States Coast Guard Headquarters

DTIC Science & Technology

2005-03-01

conversations over data networks . Many organizations are replacing portions of their traditional phone systems to gain the benefits of cost savings and...relevant to the Coast Guard. It includes the discussion of the public switched telephone network , an overview of IPT, IPT security issues, the...transmitting voice conversations over data networks . Many organizations are replacing portions of their traditional phone systems to gain the benefits of

Numerical Modeling and Combustion Studies of Scram Jet Simulation

DTIC Science & Technology

2014-12-01

and this work is dedicated to them. xiii Chapter 1 1 Introduction 1.1 Background and Overview Scramjet ( Supersonic Combustion Ramjet) is a type of...engine that op- erates under supersonic airflow conditions. The efficiency in its propulsion system over ramjet has made it a very active research...from the boundary layer of the wall [41]. Moreover, when the crossflow is supersonic , as is the case in the Scramjet configuration, some additional

Possible Applications of Soil Remediation Technologies in Latvia

NASA Astrophysics Data System (ADS)

Burlakovs, Juris; Vircavs, Magnuss

2011-01-01

Increasing public concern about deleterious effects of contamination on the environment and human health has led to legislative actions aimed at controlling and regulating the emission of potential contaminants into the environment, but there is still a plethora of territories historically contaminated with different contaminants within the territory of Latvia. The purpose of the present study is to give an overview of the formerly and presently contaminated areas and give some recommendations for remediation. 242 first category contaminated territories (the contamination exceeds the acceptable normative 10 times or more) are mentioned in the National Register of Contaminated Territories, a lot of them are known as contaminated with hazardous contaminants such as heavy metals, oil products, organic compounds and other contaminants in different amounts and concentrations. An overview of soil contamination in Latvia is provided, the planned and recommended research, as well as the planned remediation in pilot case studies, are described, giving a review of the historical contamination situation and of applications of the planned remediation technologies.

Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

PubMed Central

Parente-Rocha, Juliana Alves; Bailão, Alexandre Melo; Amaral, André Correa; Paccez, Juliano Domiraci; Borges, Clayton Luiz

2017-01-01

Diseases caused by fungi can occur in healthy people, but immunocompromised patients are the major risk group for invasive fungal infections. Cases of fungal resistance and the difficulty of treatment make fungal infections a public health problem. This review explores mechanisms used by fungi to promote fungal resistance, such as the mutation or overexpression of drug targets, efflux and degradation systems, and pleiotropic drug responses. Alternative novel drug targets have been investigated; these include metabolic routes used by fungi during infection, such as trehalose and amino acid metabolism and mitochondrial proteins. An overview of new antifungal agents, including nanostructured antifungals, as well as of repositioning approaches is discussed. Studies focusing on the development of vaccines against antifungal diseases have increased in recent years, as these strategies can be applied in combination with antifungal therapy to prevent posttreatment sequelae. Studies focused on the development of a pan-fungal vaccine and antifungal drugs can improve the treatment of immunocompromised patients and reduce treatment costs. PMID:28694566

Diabetes mellitus associated with processed and unprocessed red meat: an overview.

PubMed

Kouvari, M; Notara, V; Kalogeropoulos, N; Panagiotakos, D B

2016-11-01

According to American Diabetes Association "as many as 1 in 3 American adults will have diabetes by 2050" imposing a serious burden on healthcare services and highlighting a substantial need to reduce "new-cases" incidence. Diabetes is inextricably linked to diet, in the prevention-spectrum. Red-meat-intake has been positively associated with reduced glycemic control. However, divergence exists among meat subtypes (i.e. fresh and processed) and the magnitude of their impact on diabetes development. The present overview attempted to summarize the latest data regarding red-meat subtypes on the examined association. Four meta-analysis and 10 prospective studies, focusing on the role of fresh and processed red meat in diabetes prevention, were selected. All of studies highlighted the aggravating role of processed meat-products in diabetes incidence, while fresh meat reached significance in only half of them. Therefore, the contribution of fresh red meat on diabetes remains inconclusive. Valid conclusions seem more robust concerning processed-meat-consumption.

Mass mortality events and the role of necrophagous invertebrates.

PubMed

Tomberlin, Jeffery K; Barton, Brandon T; Lashley, Marcus A; Jordan, Heather R

2017-10-01

Scale is important in understanding and applying concepts in ecology. Historically, the mechanisms regulating necrophagous arthropod community structure have been well explored on a single vertebrate carcass. However, practically nothing is known of whether such findings can be extrapolated to cases where large numbers of carcasses have been introduced into an ecosystem at a single time point. With the increasing incidences of mass mortality events (MMEs), understanding how scale effects community assembly of necrophagous insects and the resulting bottom-up or top-down effects on the impacted ecosystem are of utmost importance. Unfortunately, MMEs are unpredictable, making their study nearly impossible within a robust experimental framework. The objectives of this paper are to provide a brief overview of what is known with regards to ecological responses to carrion, opine on the ramifications of MMEs on local communities, and provide a brief overview of knowledge gaps, avenues for future research, and a potential study systems for rigorous MME experiments. Copyright © 2017 Elsevier Inc. All rights reserved.

An overview of STRUCTURE: applications, parameter settings, and supporting software

PubMed Central

Porras-Hurtado, Liliana; Ruiz, Yarimar; Santos, Carla; Phillips, Christopher; Carracedo, Ángel; Lareu, Maria V.

2013-01-01

Objectives: We present an up-to-date review of STRUCTURE software: one of the most widely used population analysis tools that allows researchers to assess patterns of genetic structure in a set of samples. STRUCTURE can identify subsets of the whole sample by detecting allele frequency differences within the data and can assign individuals to those sub-populations based on analysis of likelihoods. The review covers STRUCTURE's most commonly used ancestry and frequency models, plus an overview of the main applications of the software in human genetics including case-control association studies (CCAS), population genetics, and forensic analysis. The review is accompanied by supplementary material providing a step-by-step guide to running STRUCTURE. Methods: With reference to a worked example, we explore the effects of changing the principal analysis parameters on STRUCTURE results when analyzing a uniform set of human genetic data. Use of the supporting software: CLUMPP and distruct is detailed and we provide an overview and worked example of STRAT software, applicable to CCAS. Conclusion: The guide offers a simplified view of how STRUCTURE, CLUMPP, distruct, and STRAT can be applied to provide researchers with an informed choice of parameter settings and supporting software when analyzing their own genetic data. PMID:23755071

Chronic Diseases Overview

MedlinePlus

... cases of blindness among adults. 6 Health Risk Behaviors that Cause Chronic Diseases Health risk behaviors are ... The Cost of Chronic Diseases and Health Risk Behaviors In the United States, chronic diseases and conditions ...

Fear of Vaginal Penetration in the Absence of Pain as a Separate Category of Female Sexual Dysfunction: A Conceptual Overview

PubMed Central

Rabinowitz, David; Lowenstein, Lior; Gruenwald, Ilan

2017-01-01

Functional sexual pain disorders in women are a particular challenge to the gynecologist, inasmuch as phobic avoidance and guarding on the part of the patient lead to difficulties in the gynecological examination and diagnosis. In some such cases examination may even be impossible. Vaginismus is the commonly diagnosed etiology of such cases. This article offers an overview of vaginismus and approaches to its treatment but also examines a subset of penetration-avoidant patients who do not appear to have a pain component. We have reviewed this separate category conceptually and clinically, and propose that this case subset be separated from the diagnosis of vaginismus and designated as vaginal penetration phobia (VPP). We further propose that this category be diagnosed as one of several possible presentations of phobic disorder, under the rubric of mental health disorder, and thus be separated from gynecology. The nosological implications are raised. PMID:28467769

Imported malaria in Scotland--an overview of surveillance, reporting and trends.

PubMed

Unger, Holger W; McCallum, Andrew D; Ukachukwu, Vincent; McGoldrick, Claire; Perrow, Kali; Latin, Gareth; Norrie, Gillian; Morris, Sheila; Smith, Catherine C; Jones, Michael E

2011-11-01

Imported malaria cases continue to occur and are often underreported. This study assessed reporting of malaria cases and their characteristics in Scotland. Cases were identified at the study sites of Aberdeen, Edinburgh, Glasgow and Inverness. The number of cases identified in the period 2003-2008 was compared to surveillance databases from Health Protection Scotland (HPS) and the Malaria Reference Laboratory (MRL). Case characteristics were recorded and analysed. Of 252 cases of malaria diagnosed and treated, an estimated 235 (93.3%) were reported to the MRL. Between 2006 and 2008, 114 of 126 cases (90.5%) were reported to HPS. Plasmodium falciparum caused 173 cases (68.7%). Business and professional travel accounted for 35.3% of cases (higher in Aberdeen), followed by visiting friends and relatives (33.1%) and holiday makers (25.5%). The majority of infections were imported from West Africa and 65.7% of patients for whom data on prophylaxis was available had taken no or inappropriate prophylaxis. Reporting of malaria in Scotland can be improved. There is a continued need to optimise preventive measures and adherence to chemoprophylaxis amongst business travellers, those visiting friends and relatives, and holiday makers in endemic countries in order to reduce imported malaria cases. Copyright © 2011 Elsevier Ltd. All rights reserved.

Update on State-Wide School Finance Cases. School Finance Project.

ERIC Educational Resources Information Center

Lawyers' Committee for Civil Rights Under Law, Washington, DC.

In May 1974, the School Finance Project of the Lawyers' Committee published a Summary of State-Wide School Finance Cases. Its purpose was to provide an overview of the field so that interested persons could quickly learn the status of school finance litigation in the several states. This was accomplished by tracing the procedural history of each…

Students with Prader-Willi Syndrome: Case Law under the IDEA

ERIC Educational Resources Information Center

Zirkel, Perry A.

2017-01-01

Prader-Willi Syndrome (PWS) is one of the low-incidence physical disabilities that the literature has not addressed in relation to the Individuals with Disabilities Education Act and its case law applications. To help fill the gap, this relatively brief article provides (a) an introduction of PWS from legal sources; (b) an overview of the IDEA,…

Poppers retinopathy.

PubMed

Luis, Joshua; Virdi, Meena; Nabili, Shahriar

2016-03-07

We present a case of a 52-year-old man with sudden, bilateral central loss of vision as a result of inhalation of 'poppers'. He was found to have characteristic changes on optical coherence tomography. With conservative treatment, the patient's vision improved marginally at 3 months follow-up. An overview of previous published cases is also included. 2016 BMJ Publishing Group Ltd.

Macro-Language Planning for Multilingual Education: Focus on Programmes and Provision

ERIC Educational Resources Information Center

Taylor-Leech, Kerry; Liddicoat, Anthony J.

2014-01-01

This overview identifies some common features of macro-level language planning and briefly summarises the changing approaches to the analysis of macro-planning in the field. It previews six cases of language-in-education planning in response to linguistic diversity presented by the contributors to this issue. The cases show how macro-planning can…

"But They Just Can't Do It": Reconciling Teacher Expectations of Latino Students

ERIC Educational Resources Information Center

Rodriguez, Mariela A.

2012-01-01

This case begins with a contextual overview of the educational plight of Latino students in U.S. public schools. This pervasive plight has economic and social implications in the lives of these students. Using a Borderlands Cultural Wealth framework, the case focuses on the educational challenges of Mexican American and immigrant students in one…

The Santa Rosa Case: Women-Only Forums on the Internet and the First Amendment.

ERIC Educational Resources Information Center

Shade, Leslie Regan

1997-01-01

Provides an overview of a case at Santa Rosa Junior College in which the U.S. Department of Education's Office of Civil Rights found that single sex Internet bulletin boards operated by educational institutions receiving federal financial assistance violate federal sex equity law. Discusses free speech, sexual harassment and women only forums, and…

Institutionalizing China's Research University through Academic Mobility: The Case of PKU

ERIC Educational Resources Information Center

Xiaoguang, Shi

2015-01-01

Academic mobility is becoming a tread in academic life and a professional development globally, regionally and nationally. This article makes use of a case university--Peking University (PKU)--as an analytical approach to explore how and why academic mobility can happen in China's research universities. The author first presents an overview of the…

Reflecting on Role Play in Geographic Education: The Case of the Banana War

ERIC Educational Resources Information Center

Kurtz, Hilda E.

2004-01-01

Debates over the nature and extent of globalization raise many issues to be addressed in a geographic education. In this paper, I briefly review case method instruction and role-play as teaching strategies suitable for material on globalization and other geographic subject matter, and then sketch an overview of an undergraduate geography role-play…

Modeling tyrosinase activity. Effect of ligand topology on aromatic ring hydroxylation: an overview.

PubMed

De, Anindita; Mandal, Sukanta; Mukherjee, Rabindranath

2008-01-01

Synthetic modeling of tyrosinase (o-phenol ring hydroxylation) has emerged as a novel class of successful biomimetic studies. It is a well-established fact that the reaction of dioxygen with copper(I) complexes of m-xylyl-based ligands generate putative copper-oxygen intermediate species such as side-on peroxo {CuII2(mu-O2)}2+ [in some cases bis-oxo {CuIII2(mu-O)2}2+ in equilibrium with isomeric side-on peroxo], due to oxygen activation. Electrophilic attack of such species brings about monooxygenase activity by incorporating one of the oxygens to m-xylyl ring of the ligand and the other oxygen is reduced to hydroxide ion. The goal of this review is to provide a concise overview of the present day knowledge in this field of research to emphasize the important role the designed ligands play in eliciting the desired tyrosinase-like chemistry.

An overview of chronic kidney disease management and CAPD in the home.

PubMed

Jain, Neerja; Simoyi, Pat

2008-05-01

Chronic kidney disease (CKD) is a common, harmful, but treatable long term condition. An overview of CKD is provided in this article. Kidney Research UK, www.kidneyresearchuk.org a national charity dedicated to research, has developed the A Better Life through Education and empowerment (ABLE) programme which seeks to research and raise awareness o the issues among 'at risk' groups as well as among relevant health professionals. Part Two of the renal NSF suggests many actions that can be taken in primary care to prevent CKD. In the event of Established Renal Failure (ERF), there are a number of treatment options available including continuous ambulatory peritoneal dialysis (CAPD), described here. Kidney Research UK's Patient DVD module two (complimentary copy attached to this issue) provides more detail using case studies. The DVD offers practical help, support and guidance on how to overcome some of the challenges.

Overview of the Temperature Response in the Mesosphere and Lower Thermosphere to Solar Activity

NASA Technical Reports Server (NTRS)

Beig, Gufran; Scheer, Juergen; Mlynczak, Martin G.; Keckhut, Philippe

2008-01-01

The natural variability in the terrestrial mesosphere needs to be known to correctly quantify global change. The response of the thermal structure to solar activity variations is an important factor. Some of the earlier studies highly overestimated the mesospheric solar response. Modeling of the mesospheric temperature response to solar activity has evolved in recent years, and measurement techniques as well as the amount of data have improved. Recent investigations revealed much smaller solar signatures and in some case no significant solar signal at all. However, not much effort has been made to synthesize the results available so far. This article presents an overview of the energy budget of the mesosphere and lower thermosphere (MLT) and an up-to-date status of solar response in temperature structure based on recently available observational data. An objective evaluation of the data sets is attempted and important factors of uncertainty are discussed.

A critical overview of the current myofascial pain literature - March 2016.

PubMed

Dommerholt, Jan; Hooks, Todd; Finnegan, Michelle; Grieve, Rob

2016-04-01

The worldwide interest in myofascial pain syndrome (MPS) and trigger points (TrPs) is reflected in the increasing number of publications. In this overview of the literature, we included 26 studies, case reports and review articles by authors from 18 different countries. Several research groups are exploring the characteristic of TrPs such as Chen and colleagues, who continued their work on the quantification of the taut bands. Meng and colleagues studied the relationships between TrPs and central sensitization, while Yu and colleagues examined the electrophysiological characteristics that occur as a result of active TrPs. Several researchers used objective measurements to determine clinical outcomes, such as Koppenhaver and colleagues who measured objective changes in the function and nociceptive sensitivity of lumbar multifidus muscle subjects with low back pain. Turo and colleagues quantified muscle tissue changes after dry needling in chronic myofascial pain using elastography. Multiple studies explored various treatment options for TrPs, such as dry needling, injections with lidocaine or granisetron, traditional Thai massage, self-myofascial release, kinesiotaping, and monochromatic infrared photo energy, among others. Copyright © 2016 Elsevier Ltd. All rights reserved.

Applied remediation of petroleum hydrocarbons 3(6)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinchee, R.E.; Kittel, J.A.; Reisinger, H.J.

1995-12-31

This volume provides sound scientific and engineering approaches. Sections of this volume cover bioremediation markets, general technology overviews, and selected case studies of crude oil spills in marine environments, heavy-metal co-contamination, steam injection, nitrate-based bioremediation, land farming, nutrient addition, confined aquifers, anaerobic biodegradation, free-product recovery technologies, bioremediation in low permeability soils and rock, biopile treatment, field-scale studies, oily waste organics as soil amendments, BTEX degradation in a biofilter, surfactant-aided recovery, mass transport in BTEX removal, electron acceptor selection and delivery strategies, and electrokinetic moisture and nutrient control in unsaturated soils.

Sleep Eduction: Treatment & Therapy

MedlinePlus

... Overview & Facts Symptoms & Causes Diagnosis & Self Tests Treatment Sleep Apnea Overview & Facts Symptoms & Risk Factors Self-Tests Diagnosis ... for a Sleep Study Testing Process & Results Home Sleep Apnea Testing Overview Testing Process & Results CPAP Overview Benefits ...

Planning, implementation, and history of the first 5 years of operation of the Craig, Alaska, pool and school biomass heating system—a case study

Treesearch

Allen M. Brackley; K. Petersen

2016-01-01

A wood-based energy project in Craig, Alaska, to heat the community's aquatic center and two of its schools was the first such installation in Alaska to convert from fossil fuels to a renewable energy source. Initial interest in the project started in 2004. The system came online in April 2008. This report provides an overview of the new heating system's...

New Zealand geothermal: Wairakei -- 40 years

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This quarterly bulletin highlights the geothermal developments in New Zealand with the following articles: A brief history of the Wairakei geothermal power project; Geothermal resources in New Zealand -- An overview; Domestic and commercial heating and bathing -- Rotorua area; Kawerau geothermal development: A case study; Timber drying at Kawerau; Geothermal greenhouses at Kawerau; Drying of fibrous crops using geothermal steam and hot water at the Taupo Lucerne Company; Prawn Park -- Taupo, New Zealand; Geothermal orchids; Miranda hot springs; and Geothermal pipeline.

RS3PE syndrome: an overview.

PubMed

Olivieri, I; Salvarani, C; Cantini, F

2000-01-01

More than ten years ago McCarty et al. described the RS3PE syndrome based on their study of 23 patients. Numerous additional cases have since been reported. In addition to the isolated or "pure" type which probably forms part of the clinical spectrum of polymyalgia rheumatica, inflammatory swelling with pitting edema of the dorsum of the hands and/or feet can be observed in different inflammatory rheumatic diseases as well as in haematological and solid malignancies.

Sports pairs: insights on athletic talent; research reviews: twins with leukemia; parents and twins.

PubMed

Segal, Nancy L

2007-06-01

Twin research exploring genetic and environmental influences on athletic interests and talents is reviewed. Illustrative examples of twin athletes representing a variety of sports activities are presented. This is followed by an overview of twin studies offering critical insights into the onset and progress of leukemia. In the last section, timely events involving twins and parents of twins will be described--each case provides a new look at an old question.

American Health Lawyers Association: the year in review 2002-2003.

PubMed

Leibold, Peter

2003-01-01

Every year, the Practice Groups of the American Health Lawyers Association assemble a Year in Review summary of the leading developments in case law, legislation, and administrative actions affecting healthcare. This Article provides a comprehensive overview of these developments. The introduction presents a "Top Ten" list of the year's most noteworthy developments. The remainder of the Article is divided into fourteen topical areas, and offers a brief overview of issues in those areas. Overall, these various developments demonstrate society's efforts to balance accountability, efficiency, and affordability in the delivery of healthcare.

Treatment- and Disease-Related Complications of Prostate Cancer

PubMed Central

Simoneau, Anne R

2006-01-01

One of the highlights of the 16th International Prostate Cancer Update was a session on treatment- and disease-related complications of prostate disease. It began with presentation of a challenging case of rising prostate-specific antigen levels after radical prostatectomy, followed by an overview of the use of zoledronic acid in prostate cancer, a review of side effects of complementary medicines, an overview of complications of cryotherapy, an assessment of complications of brachytherapy and external beam radiation therapy, and a comparison of laparoscopy versus open prostatectomy. PMID:17021643

Considerations for conducting epidemiologic case-control studies of cancer in developing countries.

PubMed

Brinton, L A; Herrero, R; Brenes, M; Montalván, P; de la Guardia, M E; Avila, A; Domínguez, I L; Basurto, E; Reeves, W C

1991-01-01

The challenges involved in conducting epidemiologic studies of cancer in developing countries can be and often are unique. This article reports on our experience in performing a case-control study of invasive cervical cancer in four Latin American countries (Columbia, Costa Rica, Mexico, and Panama), the summary medical results of which have been published in a previous issue of this journal (1). The study involved a number of principal activities--mainly selecting, conducting interviews with, and obtaining appropriate biologic specimens from 759 cervical cancer patients, 1,467 matched female controls, and 689 male sex partners of monogamous female subjects. This presentation provides an overview of the planning and methods used to select the subjects, conduct the survey work, and obtain complete and effectively unbiased data. It also points out some of the important advantages and disadvantages of working in developing areas similar to those serving as locales for this study.

An experimental investigation of the flow physics of high-lift systems

NASA Technical Reports Server (NTRS)

Thomas, Flint O.; Nelson, R. C.

1995-01-01

This progress report is a series of overviews outlining experiments on the flow physics of confluent boundary layers for high-lift systems. The research objectives include establishing the role of confluent boundary layer flow physics in high-lift production; contrasting confluent boundary layer structures for optimum and non-optimum C(sub L) cases; forming a high quality, detailed archival data base for CFD/modelling; and examining the role of relaminarization and streamline curvature. Goals of this research include completing LDV study of an optimum C(sub L) case; performing detailed LDV confluent boundary layer surveys for multiple non-optimum C(sub L) cases; obtaining skin friction distributions for both optimum and non-optimum C(sub L) cases for scaling purposes; data analysis and inner and outer variable scaling; setting-up and performing relaminarization experiments; and a final report establishing the role of leading edge confluent boundary layer flow physics on high-lift performance.

Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature.

PubMed

Cabral, Andrea Maria; da Siveira Rioja, Suzimar; Brito-Santos, Fabio; Peres da Silva, Juliana Ribeiro; MacDowell, Maria Luíza; Melhem, Marcia S C; Mattos-Guaraldi, Ana Luíza; Hirata Junior, Raphael; Damasco, Paulo Vieira

2017-11-01

Introduction. Endocarditis caused by yeasts is currently an emerging cause of infective endocarditis and, when accompanied byfever of unknown origin, is more severe since interferes with proper diagnosis and endocarditis treatment. Case presentation. The Rio de Janeiro Infective Endocarditis Study Group reports a case of infectious endocarditis (IE) with negative blood cultures in a 45-year-old white female resident in Rio de Janeiro, Brazil, previously submitted to kidney transplantation. After diagnosis and intervention, the valve culture revealed Rhodotorula mucilaginosa . The clinical aspects and overview of endocarditis caused by Rhodotorula spp. demonstrated that R. muscilaginosa have been isolated from the last IE cases from kidney transplanted patients. Conclusion. Though most of the patients (in literature) recovered well from endocarditis caused by Rhodotorula spp., physicians must be aware for diagnosis of fungemia and fungal treatment in kidney transplanted patients suffering of fever of unknown origin in the modern immunosuppressive treatment.

Garmin : Market Diversification & Use Case Overview

DOT National Transportation Integrated Search

2018-01-25

Garmins aviation GPS products support both surface and airborne applications. Garmin produces FAA certified and non-certified equipment for the General Aviation market, including both fixed-wing and rotorcraft platforms. Aside from instrument appr...

An Epidemiological Overview of Chronic Obstructive Pulmonary Disease: What Can Real-Life Data Tell Us about Disease Management?

PubMed

Soriano, Joan B

2017-03-15

Chronic obstructive pulmonary disease (COPD) is a common condition, associated with increasing age and smoking exposure. COPD is a leading cause of morbidity, mortality and health care expenditure worldwide; yet, only 10-15% of all cases are identified medically. Alpha-1-antitrypsin deficiency (AATD) is responsible for about 1% of COPD cases but is also largely under-recognised, leading to diagnostic delay and missed treatment opportunities in patients who remain undetected. New evidence has recently highlighted the extent of overlap between COPD and bronchiectasis and the implications of comorbidity on clinical course and mortality. COPD with comorbid bronchiectasis deserves to be given research priority. This article overviews the epidemiology of COPD and examines the implications of overlap between COPD and AATD and between COPD and bronchiectasis.

On-Line Modal State Monitoring of Slowly Time-Varying Structures

NASA Technical Reports Server (NTRS)

Johnson, Erik A.; Bergman, Lawrence A.; Voulgaris, Petros G.

1997-01-01

Monitoring the dynamic response of structures is often performed for a variety of reasons. These reasons include condition-based maintenance, health monitoring, performance improvements, and control. In many cases the data analysis that is performed is part of a repetitive decision-making process, and in these cases the development of effective on-line monitoring schemes help to speed the decision-making process and reduce the risk of erroneous decisions. This report investigates the use of spatial modal filters for tracking the dynamics of slowly time-varying linear structures. The report includes an overview of modal filter theory followed by an overview of several structural system identification methods. Included in this discussion and comparison are H-infinity, eigensystem realization, and several time-domain least squares approaches. Finally, a two-stage adaptive on-line monitoring scheme is developed and evaluated.

Restless Legs Syndrome -- Self-Tests and Diagnosis

MedlinePlus

... Overview & Facts Symptoms & Causes Diagnosis & Self Tests Treatment Sleep Apnea Overview & Facts Symptoms & Risk Factors Self-Tests Diagnosis ... for a Sleep Study Testing Process & Results Home Sleep Apnea Testing Overview Testing Process & Results CPAP Overview Benefits ...

Find a Sleep Center Near You

MedlinePlus

... Overview & Facts Symptoms & Causes Diagnosis & Self Tests Treatment Sleep Apnea Overview & Facts Symptoms & Risk Factors Self-Tests Diagnosis ... for a Sleep Study Testing Process & Results Home Sleep Apnea Testing Overview Testing Process & Results CPAP Overview Benefits ...

Missed Diagnosis of Syrinx

PubMed Central

Oh, Chang Hyun; Kim, Chan Gyu; Lee, Jae-Hwan; Park, Hyeong-Chun; Park, Chong Oon

2012-01-01

Study Design Prospective, randomized, controlled human study. Purpose We checked the proportion of missed syrinx diagnoses among the examinees of the Korean military conscription. Overview of Literature A syrinx is a fluid-filled cavity within the spinal cord or brain stem and causes various neurological symptoms. A syrinx could easily be diagnosed by magnetic resonance image (MRI), but missed diagnoses seldom occur. Methods In this study, we reviewed 103 cases using cervical images, cervical MRI, or whole spine sagittal MRI, and syrinxes was observed in 18 of these cases. A review of medical certificates or interviews was conducted, and the proportion of syrinx diagnoses was calculated. Results The proportion of syrinx diagnoses was about 66.7% (12 cases among 18). Missed diagnoses were not the result of the length of the syrinx, but due to the type of image used for the initial diagnosis. Conclusions The missed diagnosis proportion of the syrinx is relatively high, therefore, a more careful imaging review is recommended. PMID:22439081

Methodological approaches in conducting overviews: current state in HTA agencies.

PubMed

Pieper, Dawid; Antoine, Sunya-Lee; Morfeld, Jana-Carina; Mathes, Tim; Eikermann, Michaela

2014-09-01

Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in international Health Technology Assessment (HTA) agencies. We identified 127 HTA agencies and scanned their websites for methodological handbooks as well as published overviews as HTA reports. Additionally, we contacted HTA agencies by e-mail to retrieve possible unidentified handbooks or other related sources. In total, eight HTA agencies providing methodological support were found. Thirteen HTA agencies were found to have produced overviews since 2007, but only six of them published more than four overviews. Overviews were mostly employed in HTA products related to rapid assessment. Additional searches for primary studies published after the last review are often mentioned in order to update results. Although the interest in overviews is rising, little methodological guidance for the conduct of overviews is provided by HTA agencies. Overviews are of special interest in the context of rapid assessments to support policy-making within a short time frame. Therefore, empirical work on overviews needs to be extended. National strategies and experience should be disclosed and discussed. Copyright © 2013 John Wiley & Sons, Ltd.

Application of geostatistics to coal-resource characterization and mine planning. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kauffman, P.W.; Walton, D.R.; Martuneac, L.

1981-12-01

Geostatistics is a proven method of ore reserve estimation in many non-coal mining areas but little has been published concerning its application to coal resources. This report presents the case for using geostatistics for coal mining applications and describes how a coal mining concern can best utilize geostatistical techniques for coal resource characterization and mine planning. An overview of the theory of geostatistics is also presented. Many of the applications discussed are documented in case studies that are a part of the report. The results of an exhaustive literature search are presented and recommendations are made for needed future researchmore » and demonstration projects.« less

[Treatment with sunitinib and hypothyroidism--a case report and overview of literature].

PubMed

Kreze, A; Stáhalová, V; Zadrazilová, A; Koskuba, J; Kosák, M

2009-01-01

In the article the authors present the case of a patient with clear cell renal carcinoma, where after nephrectomy local metastases appeared. The treatment of choice was sunitinib. After 20 cycles of therapy heavy hypothyroidism was verified which required substitution by thyroxine. Elevated levels of TSH appeared in up to 70% and hypothyrodism in up to 40% of thus treated patients. Also described is the mechanism of action of sunitinib. There seems to exist a correlation between the "adverse effects" of the drug and a better result of the therapy of cancer, however, prospective studies are absent. Most experts agree that the thyroid function during treatment with sunitinib needs to be monitored.

Mandated Mental Health Insurance: A Complex Case of Pros and Cons. Human Resources Series.

ERIC Educational Resources Information Center

Paterson, Andrea

1986-01-01

The pros and cons of state laws mandating mental health insurance are discussed in this report. The history of a 1985 Supreme Court case which held that states could mandate mental health benefits introduces the report. In an overview of the issue, the long-standing argument between the insurance industry and the mental health establishment is…

Nitrates and Nitrites TNC Presentation

EPA Pesticide Factsheets

The Nitrates and Nitrites Presentation gives an overview of nitrates and nitrites in drinking water, why it is important to monitor them and what to do in cases where the results exceed the maximum contaminant level (MCL).

Diarrheal Diseases - Acute and Chronic

MedlinePlus

... Topic / Diarrheal Diseases – Acute and Chronic Diarrheal Diseases – Acute and Chronic Basics Resources Overview Acute diarrhea is ... bulky, greasy or very bad smelling stools. Causes – Acute Diarrhea Most cases of acute, watery diarrhea are ...

Genetics Home Reference: autosomal dominant nocturnal frontal lobe epilepsy

MedlinePlus

... brain are involved in many critical functions, including reasoning, planning, judgment, and problem-solving. It is unclear ... E, Montagna P. Nocturnal frontal lobe epilepsy. A clinical and polygraphic overview of 100 consecutive cases. Brain. ...

Recap and Program Plan Update

DOT National Transportation Integrated Search

2015-03-12

Initial Workshop-I held on September 18, 2014 at the Volpe Center - Overview of DOT GPS Adjacent Band Compatibility Assessment Plan and plans/timeline for implementation - Presentation on GPS use cases and list of representative GPS receivers - Descr...

Interventions to Improve Neonatal Health and Later Survival: An Overview of Systematic Reviews.

PubMed

Lassi, Zohra S; Middleton, Philippa F; Crowther, Caroline; Bhutta, Zulfiqar A

2015-08-01

Evidence-based interventions and strategies are needed to improve child survival in countries with a high burden of neonatal and child mortality. An overview of systematic reviews can focus implementation on the most effective ways to increase child survival. In this overview we included published Cochrane and other systematic reviews of experimental and observational studies on antenatal, childbirth, postnatal and child health interventions aiming to prevent perinatal/neonatal and child mortality using the WHO list of essential interventions. We assessed the methodological quality of the reviews using the AMSTAR criteria and assessed the quality of the outcomes using the GRADE approach. Based on the findings from GRADE criteria, interventions were summarized as effective, promising or ineffective. The overview identified 148 Cochrane and other systematic reviews on 61 reproductive, maternal, newborn and child health interventions. Of these, only 57 reviews reported mortality outcomes. Using the GRADE approach, antenatal corticosteroids for preventing neonatal respiratory distress syndrome in preterm infants; early initiation of breastfeeding; hygienic cord care; kangaroo care for preterm infants; provision and promotion of use of insecticide treated bed nets (ITNs) for children; and vitamin A supplementation for infants from six months of age, were identified as clearly effective interventions for reducing neonatal, infant or child mortality. Antenatal care, tetanus immunization in pregnancy, prophylactic antimalarials during pregnancy, induction of labour for prolonged pregnancy, case management of neonatal sepsis, meningitis and pneumonia, prophylactic and therapeutic use of surfactant, continuous positive airway pressure for neonatal resuscitation, case management of childhood malaria and pneumonia, vitamin A as part of treatment for measles associated pneumonia for children above 6 months, and home visits across the continuum of care, were identified as promising interventions for reducing neonatal, infant, child or perinatal mortality. Comprehensive adoption of the above six effective and 11 promising interventions can improve neonatal and child survival around the world. Choice of intervention and degree of implementation currently depends on resources available and policies in individual countries and geographical settings. This review was part of doctoral thesis which was funded by University of Adelaide, Australia.

Building America Case Study: Cold Climate Foundation Wall Hygrothermal Research Facility, Cloquet, Minnesota (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NorthernSTAR

2014-09-01

This report focuses on the progress made to date and the technical details of the experiment. An overview of the experimental data being collected with some interesting highlights noted thus far is also provided. A full analysis of the experimental data and the drawing of conclusions with regard to the thermal and hygrothermal performance of the retrofit foundation insulation systems tested will only be possible after a full year of data has been collected in 2014.

Solitary morphea profunda following trauma sustained in an automobile accident.

PubMed

Touloei, Khasha; Wiener, Adam; Glick, Bradley P

2015-01-01

Solitary morphea profunda (SMP) is a variant of localized scleroderma (LS). We report the case of a 50-year-old white woman with a history of trauma sustained in an automobile accident who presented with SMP on the right upper arm. We also provide a review of the classification, epidemiology, etiology, diagnostic studies, pathogenesis, physical findings, histopathology, treatment, and prognosis of SMP, along with other important details pertaining to the disease. We also provide a brief overview of LS and morphea profunda (MP).

Evolutionary approach to communication between humans and dogs.

PubMed

Lakatos, Gabriella

2011-01-01

Dog-human communication has been widely investigated recently for different theoretical reasons, in most cases through dogs' comprehension of human gestural cues. Dogs have been reported to be very skilful in comprehending a variety of human pointing gestures in many independent studies. This paper provides a short overview of the possible explanations behind the dogs' exceptional communicational abilities towards humans from an evolutionary perspective, concluding that the different and seemingly contradictory hypotheses are not exclusive but they might have a synergic effect.

Benchmarking: measuring the outcomes of evidence-based practice.

PubMed

DeLise, D C; Leasure, A R

2001-01-01

Measurement of the outcomes associated with implementation of evidence-based practice changes is becoming increasingly emphasized by multiple health care disciplines. A final step to the process of implementing and sustaining evidence-supported practice changes is that of outcomes evaluation and monitoring. The comparison of outcomes to internal and external measures is known as benchmarking. This article discusses evidence-based practice, provides an overview of outcomes evaluation, and describes the process of benchmarking to improve practice. A case study is used to illustrate this concept.

Bacterial molecular networks: bridging the gap between functional genomics and dynamical modelling.

PubMed

van Helden, Jacques; Toussaint, Ariane; Thieffry, Denis

2012-01-01

This introductory review synthesizes the contents of the volume Bacterial Molecular Networks of the series Methods in Molecular Biology. This volume gathers 9 reviews and 16 method chapters describing computational protocols for the analysis of metabolic pathways, protein interaction networks, and regulatory networks. Each protocol is documented by concrete case studies dedicated to model bacteria or interacting populations. Altogether, the chapters provide a representative overview of state-of-the-art methods for data integration and retrieval, network visualization, graph analysis, and dynamical modelling.

Improving ostomates' confidence with a discharge-solidifying agent.

PubMed

Slater, Rebecca

Not every person with a stoma will develop problems or even feel that he or she is unable to manage a stoma independently. However, for the individual who does experience problems and struggles to cope, the stoma nurse is pivotal in providing resources and product experience. He or she can enable the ostomate to adapt to the stoma and maintain their quality of life. This article provides an overview of a solidifying agent and case studies illustrating how it can be used to help patients achieve independence.

Historical linguistics in Australia: trees, networks and their implications

PubMed Central

Bowern, Claire

2010-01-01

This paper presents an overview of the current state of historical linguistics in Australian languages. Australian languages have been important in theoretical debates about the nature of language change and the possibilities for reconstruction and classification in areas of intensive diffusion. Here are summarized the most important outstanding questions for Australian linguistic prehistory; I also present a case study of the Karnic subgroup of Pama–Nyungan, which illustrates the problems for classification in Australian languages and potential approaches using phylogenetic methods. PMID:21041209

Historical linguistics in Australia: trees, networks and their implications.

PubMed

Bowern, Claire

2010-12-12

This paper presents an overview of the current state of historical linguistics in Australian languages. Australian languages have been important in theoretical debates about the nature of language change and the possibilities for reconstruction and classification in areas of intensive diffusion. Here are summarized the most important outstanding questions for Australian linguistic prehistory; I also present a case study of the Karnic subgroup of Pama-Nyungan, which illustrates the problems for classification in Australian languages and potential approaches using phylogenetic methods.

Science with MATISSE

NASA Astrophysics Data System (ADS)

Wolf, Sebastian; Lopez, Bruno; Augereau, Jean-Charles; Delbo, Marco; Dominik, Carsten; Henning, Thomas; Hofmann, Karl-Heinz; Hogerheijde, Michiel; Hron, Josef; Jaffe, Walter; Lanz, Thierry; Meisenheimer, Klaus; Millour, Florentin; Pantin, Eric; Petrov, Roman; Schertl, Dieter; van Boekel, Roy; Weigelt, Gerd; Chiavassa, Andrea; Juhasz, Attila; Matter, Alexis; Meilland, Anthony; Nardetto, Nicolas; Paladini, Claudia

2016-07-01

We present an overview of the scientific potential of MATISSE, the Multi Aperture mid-Infrared SpectroScopic Experiment for the Very Large Telescope Interferometer. For this purpose we outline selected case studies from various areas, such as star and planet formation, active galactic nuclei, evolved stars, extrasolar planets, and solar system minor bodies and discuss strategies for the planning and analysis of future MATISSE observations. Moreover, the importance of MATISSE observations in the context of complementary high-angular resolution observations at near-infrared and submillimeter/millimeter wavelengths is highlighted.

Local Gov`t assistance in commercial waste reduction & recycling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hannah, C.W.

This paper outlines programs and strategies for reducing the waste stream by targeting the commercial, industrial and institutional sectors. The programs described are implemented by the Wake County Solid Waste Management Division, North Carolina. Findings and recommendations of a task force focusing on the role of the private sector in meeting state waste reduction mandates are summarized. Commercial initiatives, educational initiatives, and a grant program are described. Several case studies are provided which overview the variety of businesses and waste materials addressed.

The LARSYS educational package: Instructor's notes. [instructional materials for training people to analyze remotely sensed data

NASA Technical Reports Server (NTRS)

Lindenlaub, J. C.; Davis, S. M.

1974-01-01

Materials are presented for assisting instructors in teaching the LARSYS Educational Package, which is a set of instructional materials to train people to analyze remotely sensed multispectral data. The seven units of the package are described. These units are: quantitative remote sensing, overview of the LARSYS software system, the 2780 remote terminal, demonstration of LARSYS on the 2780 remote terminal, exercises, guide to multispectral data analysis, and a case study using LARSYS for analysis of LANDSAT data.

Case for Deploying Complex Systems Utilizing Commodity Components

NASA Technical Reports Server (NTRS)

Bryant, Barry S.; Pitts, R. Lee; Ritter, George

2003-01-01

This viewgraph representation presents a study of the transition of computer networks and software engineering at the Huntsville Operations Support Center (HOSC) from a client/server UNIX based system to a client/server system based on commodity priced and open system components. Topics covered include: an overview of HOSC ground support systems, an analysis for changes to the existing ground support system, an analysis of options considered for the transition to a new system, and a consideration of goals for a new system.

Telerehabilitation store and forward applications: a review of applications and privacy considerations in physical and occupational therapy practice.

PubMed

Peterson, Christopher; Watzlaf, Valerie

2014-01-01

An overview of store and forward applications commonly used in physical and occupational therapy practice is reviewed with respect to regulation, privacy, security, and clinical applications. A privacy and security checklist provides a clear reference of pertinent regulatory issues regarding these software applications. A case study format is used to highlight clinical applications of store and forward software features. Important considerations of successful implementation of store and forward applications are also identified and discussed.

An Approach for Identifying and Characterising Problems in the Iterative Development of C3l Capability.

DTIC Science & Technology

1999-11-01

OverviewNo. 23/1998, Australian Department of Defence. Denzin , N. K. and Y. S. Lincoln , Eds. (1994). Handbook of Qualitative Research. SAGE...Frey (1994). Interviewing: The Art of Science. In Handbook of Qualitative Research. (N. K. Denzin and Y. S. Lincoln . Eds.), pp. 377-392, SAGE...general. Yin’s book (1994) on case studies is worth reading, and Denzin (1994) provides a more detailed collection of papers on specific techniques, such

Coastal Frontogenesis and Associated Severe Weather on 13 March 1986 (GALE IOP 13)

DTIC Science & Technology

1989-01-01

facilities used in this research are described as follows: a) Sounding operations The GALE sounding operations were designed to provide three-dimensional...airplanes were developed for a variety of weather scenarios. These tracks were designed to provide, but were not limited to, in situ measurements of...NU PA NJ Figur 2.. TpgahMfIh otesen ntdSae D ikea .,18) 32 3. CASE STUDY 3.1 Synoptic Overview On 12 March 1986 a back-door cold front (Carr, 1951

Emergency department injury surveillance and aetiological research: bridging the gap with the two-stage case-control study design.

PubMed

Hagel, Brent E

2011-04-01

To provide an overview of the two-stage case-control study design and its potential application to ED injury surveillance data and to apply this approach to published ED data on the relation between brain injury and bicycle helmet use. Relevant background is presented on injury aetiology and case-control methodology with extension to the two-stage case-control design in the context of ED injury surveillance. The design is then applied to data from a published case-control study of the relation between brain injury and bicycle helmet use with motor vehicle involvement considered as a potential confounder. Taking into account the additional sampling at the second stage, the adjusted and corrected odds ratio and 95% confidence interval for the brain injury-helmet use relation is presented and compared with the estimate from the entire original dataset. Contexts where the two-stage case-control study design might be most appropriately applied to ED injury surveillance data are suggested. The adjusted odds ratio for the relation between brain injury and bicycle helmet use based on all data (n = 2833) from the original study was 0.34 (95% CI 0.25 to 0.46) compared with an estimate from a two-stage case-control design of 0.35 (95% CI 0.25 to 0.48) using only a fraction of the original subjects (n = 480). Application of the two-stage case-control study design to ED injury surveillance data has the potential to dramatically reduce study time and resource costs with acceptable losses in statistical efficiency.

[Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (dipnech) - an overview of the cases diagnosed at the department of thoracic surgery in the years 2010-2014].

PubMed

Stefański, Mariusz; Bruliński, Krzysztof; Stefańska, Marianna

Pulmonary neuroendocrine cells (PNEC) are present in the normal lungs with the incidence of 1 in 2500 epithelial cells. They usually proliferate in the presence of reactive processes related to inflammation and fibrosis of the lung parenchyma. The division of pulmonary neuroendocrine cell hyperplasia proposed by Travis et al. additionally distinguished diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) or proliferation that occurs in people without reactive hyperplasia risk factors. The confirmation of the DIPNECH diagnosis requires staining of biopsy specimens using the immunohistochemical technique for neuroendocrine markers. The aim of this study is to overview the cases of 5 patients in whom the histopathological DIPNECH diagnosis was made in the process of invasive diagnostics performed at the Department of Thoracic Surgery. The aim of the study is to evaluate typical clinical, functional, radiological and histopathological features of this rare disease syndrome. In the period from April 2010 to June 2014, five patients with lesions in the lungs were subjected to invasive diagnostics. Histopathological and immunohistochemical examinations of the collected specimens were used to make the DIPNECH diagnosis in these patients. The natural history of the disease was traced based on a 5-year follow-up in one of the patients. In addition, we analyzed the literature with regard to the described cases. Thanks to the early diagnosis of non-specific lesions in the lungs, typical carcinoid which develops on the basis of discussed DIPNECH, was found in the resected material in two out of five operated patients. The accurate diagnosis of DIPNECH allows for the implementation of appropriate treatment and channels further management of the patient into the right direction.

Kinematic models of the upper limb joints for multibody kinematics optimisation: An overview.

PubMed

Duprey, Sonia; Naaim, Alexandre; Moissenet, Florent; Begon, Mickaël; Chèze, Laurence

2017-09-06

Soft tissue artefact (STA), i.e. the motion of the skin, fat and muscles gliding on the underlying bone, may lead to a marker position error reaching up to 8.7cm for the particular case of the scapula. Multibody kinematics optimisation (MKO) is one of the most efficient approaches used to reduce STA. It consists in minimising the distance between the positions of experimental markers on a subject skin and the simulated positions of the same markers embedded on a kinematic model. However, the efficiency of MKO directly relies on the chosen kinematic model. This paper proposes an overview of the different upper limb models available in the literature and a discussion about their applicability to MKO. The advantages of each joint model with respect to its biofidelity to functional anatomy are detailed both for the shoulder and the forearm areas. Models capabilities of personalisation and of adaptation to pathological cases are also discussed. Concerning model efficiency in terms of STA reduction in MKO algorithms, a lack of quantitative assessment in the literature is noted. In priority, future studies should concern the evaluation and quantification of STA reduction depending on upper limb joint constraints. Copyright © 2016 Elsevier Ltd. All rights reserved.

Overview of Materials Qualification Needs for Metal Additive Manufacturing

NASA Astrophysics Data System (ADS)

Seifi, Mohsen; Salem, Ayman; Beuth, Jack; Harrysson, Ola; Lewandowski, John J.

2016-03-01

This overview highlights some of the key aspects regarding materials qualification needs across the additive manufacturing (AM) spectrum. AM technology has experienced considerable publicity and growth in the past few years with many successful insertions for non-mission-critical applications. However, to meet the full potential that AM has to offer, especially for flight-critical components (e.g., rotating parts, fracture-critical parts, etc.), qualification and certification efforts are necessary. While development of qualification standards will address some of these needs, this overview outlines some of the other key areas that will need to be considered in the qualification path, including various process-, microstructure-, and fracture-modeling activities in addition to integrating these with lifing activities targeting specific components. Ongoing work in the Advanced Manufacturing and Mechanical Reliability Center at Case Western Reserve University is focusing on fracture and fatigue testing to rapidly assess critical mechanical properties of some titanium alloys before and after post-processing, in addition to conducting nondestructive testing/evaluation using micro-computerized tomography at General Electric. Process mapping studies are being conducted at Carnegie Mellon University while large area microstructure characterization and informatics (EBSD and BSE) analyses are being conducted at Materials Resources LLC to enable future integration of these efforts via an Integrated Computational Materials Engineering approach to AM. Possible future pathways for materials qualification are provided.

Meeting the challenges of case management with remote patient monitoring technology.

PubMed

Cherry, J C; Colliflower, S J; Tsiperfal, A

2000-01-01

The article presents an overview of some of the current trends in health care and the challenges faced by nurse case managers who are providing disease management services. It discusses some of the emerging technologies available today for innovative case management. In particular, this article describes a program run by a healthcare system in Sacramento, California that uses an Internet-based technology to enhance their nurse case management model. The article demonstrates how the Health Hero platform enables interactive communication between nurse case managers and their patients, thereby meeting some of the challenges the nurse case managers are faced with in the modern disease-management world.

Space benefits: The secondary application of aerospace technology in other sectors of the economy

NASA Technical Reports Server (NTRS)

1976-01-01

A 'Benefit Briefing Notebook' was prepared for the NASA Technology Utilization Office to provide accurate, convenient, and integrated resource information on the transfer of aerospace technology to other sectors of the U.S. economy. The contents are divided into three sections: (1) transfer overview, (2) benefit cases, and (3) indexes. The transfer overview section provides a general perspective for technology transfer from NASA to other organizations. In addition to a description of the basic transfer modes, the selection criteria for notebook examples and the kinds of benefit data they contain are also presented. The benefits section is subdivided into nineteen subject areas. Each subsection presents one or more key issues of current interest, with discrete transfer cases related to each key issue. Additional transfer examples relevant to each subject area are then presented. Pertinent transfer data are given at the end of each example.

The Contemporary Setting for Water Management in the West: An Overview

NASA Astrophysics Data System (ADS)

Cummings, Ronald G.

1985-11-01

The socioeconomic, legal, and institutional settings for water resources management and use in the United States have undergone dramatic changes over recent years. The resulting confusion and uncertainties in terms of the structure of water rights, the prerogatives of sovereign states, and the limitations of state-federal interfaces provide the raison d'être for the collection of papers in this special section of Water Resources Research. This special issue is intended to serve several purposes: to inform, to provoke, and to invite. Thus many readers may find new and informative Tarlock's [this issue] overview of the evolution of groundwater law from English Common Law to laws based on notions of "reasonable use" and "sharing"; of particular importance is the readers appreciation of the changes and uncertainties in water law associated with the 1982 decision in Sporhase and in the later El Paso case. These cases, marking an end of the "immunity theory" wherein states were immune, in cases involving resources use, from challenges under the Commerce Clause, give rise to Tarlock's concern with the question, Might current conditions give rise to federal control of groundwater?

Richter’s Hernia and Sir Frederick Treves: An Original Clinical Experience, Review, and Historical Overview

PubMed Central

Steinke, Wolfgang; Zellweger, René

2000-01-01

Objective To describe the clinical recognition, pathology, and management of Richter’s hernia and to review the relevant literature of the past 400 years. Summary Background Data The earliest known reported case of Richter’s hernia occurred in 1598 and was described by Fabricius Hildanus. The first scientific description of this particular hernia was given by August Gottlob Richter in 1778, who presented it as “the small rupture.” In 1887, Sir Frederick Treves gave an excellent overview on the topic and proposed the title “Richter’s hernia.” To his work—a cornerstone to modern understanding—hardly any new aspects can be added today. Since then, only occasional case reports or small series of retrospectively collected Richter’s hernias have been published. Methods The authors draw on their experience with 18 prospectively collected cases treated in the ICRC Lopiding Hospital for War Surgery in northern Kenya between February and December 1998 and review the relevant literature of the past 400 years. Results The classic features of Richter’s hernia were confirmed in all case studies of patients: only part of the circumference of the bowel is entrapped and strangulated in the hernial orifice. The involved segment may rapidly pass into gangrene, yet signs of intestinal obstruction are often absent. The death rate in the authors’ collective was 17%. Conclusion Richter’s hernia is a deceptive entity whose high death rate can be reduced by accurate diagnosis and early surgery. Considering the increasing incidence at laparoscope insertion sites, awareness of this special type of hernia with its misleading clinical appearance is important and of general interest. PMID:11066144

Solving crimes with hypnosis.

PubMed

Wester, William C; Hammond, D Corydon

2011-04-01

Following a brief review of the literature on hypnosis and memory, this paper overviews the procedures that are used in conducting forensic hypnosis interviews. Ten forensic hypnosis cases are then described. These real world cases are in stark contrast to research done in an artificial laboratory setting where the information to be recalled lacks personal relevance and was not associated with emotionally arousing situations. These cases illustrate how forensic hypnosis can result in obtaining important additional investigative leads which lead to the solving of crimes.

Patent eligibility of stem cells in Europe: where do we stand after 8 years of case law?

PubMed

Storz, Ulrich; Faltus, Timo

2017-01-01

Since 2006, some of the highest ranking European Courts have issued decisions related to the patent eligibility of human embryonic stem cells. The question of patent eligibility of human embryonic stem cells remains, however, still erratic, at least in some aspects. This article will give a short comprehensive overview of the case history, and discuss questions still unsolved.

Case-Based Learning in Endocrine Physiology: An Approach toward Self-Directed Learning and the Development of Soft Skills in Medical Students

ERIC Educational Resources Information Center

Gade, Shubhada; Chari, Suresh

2013-01-01

The Medical Council of India, in the recent "Vision 2015" document, recommended curricular reforms for undergraduates. Case-based learning (CBL) is one method where students are motivated toward self-directed learning and to develop analytic and problem-solving skills. An overview of thyroid physiology was given in a didactic lecture. A…

Benefits briefing notebook: The secondary application of aerospace technology in other sectors of the economy

NASA Technical Reports Server (NTRS)

1976-01-01

Resource information on the transfer of aerospace technology to other sectors of the U.S. economy is presented. The contents of this notebook are divided into three sections: (1) benefit cases, (2) transfer overview, and (3) indexes. Transfer examples relevant to each subject area are presented. Pertinent transfer data are given. The Transfer Overview section provides a general perspective for technology transfer from NASA to other organizations. In addition to a description of the basic transfer modes, the selection criteria for notebook examples and the kinds of benefit data they contain are also presented.

Radiation oncology in Canada.

PubMed

Giuliani, Meredith; Gospodarowicz, Mary

2018-01-01

In this article we provide an overview of the Canadian healthcare system and the cancer care system in Canada as it pertains to the governance, funding and delivery of radiotherapy programmes. We also review the training and practice for radiation oncologists, medical physicists and radiation therapists in Canada. We describe the clinical practice of radiation medicine from patients' referral, assessment, case conferences and the radiotherapy process. Finally, we provide an overview of the practice culture for Radiation Oncology in Canada. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Cosmetic tail docking: an overview of abuse and report of an interesting case.

PubMed

Eyarefe, Oghenemega David; Oguntoye, Cecilia O

2016-02-29

This paper presents an overview of the global controversies surrounding cosmetic tail docking in puppies, some observed inconsistent practices among dog breeders and Veterinarians in West Africa, and the need for the African Veterinary Profession to take a decisive position on the cosmetic docking procedure. An interesting report of observed complications associated with cosmetic tail docking in a 3 week old male Boerboel is reported alongside the management of the ensuing complications. This paper highlights the still prevalent practice of cosmetic tail docking and seeks to enlighten clinicians towards stemming its abuse in Africa.

Effect of using cardiovascular risk scoring in routine risk assessment in primary prevention of cardiovascular disease: protocol for an overview of systematic reviews.

PubMed

Studziński, Krzysztof; Tomasik, Tomasz; Krzyszton, Janusz; Jóźwiak, Jacek; Windak, Adam

2017-03-08

Major clinical practice guidelines recommend assessing risk of cardiovascular disease (CVD) using absolute/global/total CVD risk scores. However, the effectiveness of using them in clinical practice, despite publication of numerous randomised controlled trials (RCTs), is still poorly understood. To summarise and analyse current knowledge in this field, we will carry out an overview of existing systematic reviews (SRs). The objective of this overview will be to assess the effect of using cardiovascular risk scoring in routine risk assessment in primary prevention of CVD compared with standard care. We will include SRs and meta-analyses which take into account RCTs and quasi-RCTs investigating the effect of using cardiovascular risk scoring in routine risk assessment in primary prevention of CVD. SRs will be retrieved from 4 bibliographical databases and reference lists of identified reviews. Additionally, the PROSPERO database will be searched for unpublished, ongoing or recently completed SRs. 2 reviewers will assess the SRs independently for eligibility and bias. The data will be extracted to a special form. Any disagreement will be resolved by discussion. In case of lack of consensus, a third author will arbitrate. The overview of SRs will be reported according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement. Ethics approval is not required for overview of SRs. We will summarise evidence concerning whether use of the absolute/global/total CVD risk scoring tools in primary prevention of CVD is effective and supported with scientific data or not. If we face unsatisfactory confirmation, we will highlight a need for further research and advice on how to plan such a study. We will submit the results of our study for peer-review publication in a journal indexed in the international bibliographic database of biomedical information. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

In-Flight Manual Electronics Repair for Deep-Space Missions

NASA Technical Reports Server (NTRS)

Pettegrew, Richard; Easton, John; Struk, Peter; Anderson, Eric

2007-01-01

Severe limitations on mass and volume available for spares on long-duration spaceflight missions will require electronics repair to be conducted at the component level, rather than at the sub-assembly level (referred to as Orbital Replacement Unit, or 'ORU'), as is currently the case aboard the International Space Station. Performing reliable component-level repairs in a reduced gravity environment by crew members will require careful planning, and some specialty tools and systems. Additionally, spacecraft systems must be designed to enable such repairs. This paper is an overview of a NASA project which examines all of these aspects of component level electronic repair. Results of case studies that detail how NASA, the U.S. Navy, and a commercial company currently approach electronics repair are presented, along with results of a trade study examining commercial technologies and solutions which may be used in future applications. Initial design recommendations resulting from these studies are also presented.

Genome research elucidating environmental adaptation: Dark-fly project as a case study.

PubMed

Fuse, Naoyuki

2017-08-01

Organisms have the capacity to adapt to diverse environments, and environmental adaptation is a substantial driving force of evolution. Recent progress of genome science has addressed the genetic mechanisms underlying environmental adaptation. Whole genome sequencing has identified adaptive genes selected under particular environments. Genome editing technology enables us to directly test the role(s) of a gene in environmental adaptation. Genome science has also shed light on a unique organism, Dark-fly, which has been reared long-term in the dark. We determined the whole genome sequence of Dark-fly and reenacted environmental selections of the Dark-fly genome to identify the genes related to dark-adaptation. Here I will give an overview of current progress in genome science and summarize our study using Dark-fly, as a case study for environmental adaptation. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ball Bearing Analysis with the ORBIS Tool

NASA Technical Reports Server (NTRS)

Halpin, Jacob D.

2016-01-01

Ball bearing design is critical to the success of aerospace mechanisms. Key bearing performance parameters, such as load capability, stiffness, torque, and life all depend on accurate determination of the internal load distribution. Hence, a good analytical bearing tool that provides both comprehensive capabilities and reliable results becomes a significant asset to the engineer. This paper introduces the ORBIS bearing tool. A discussion of key modeling assumptions and a technical overview is provided. Numerous validation studies and case studies using the ORBIS tool are presented. All results suggest the ORBIS code closely correlates to predictions on bearing internal load distributions, stiffness, deflection and stresses.

Genes contributing to the development of alcoholism: an overview.

PubMed

Edenberg, Howard J

2012-01-01

Genetic factors (i.e., variations in specific genes) account for a substantial portion of the risk for alcoholism. However, identifying those genes and the specific variations involved is challenging. Researchers have used both case-control and family studies to identify genes related to alcoholism risk. In addition, different strategies such as candidate gene analyses and genome-wide association studies have been used. The strongest effects have been found for specific variants of genes that encode two enzymes involved in alcohol metabolism-alcohol dehydrogenase and aldehyde dehydrogenase. Accumulating evidence indicates that variations in numerous other genes have smaller but measurable effects.

Recap, One-on-One Discussions, and Moving Forward

DOT National Transportation Integrated Search

2014-12-04

Recap. Initial WorkshopI held on September 18, 2014 at the Volpe Center. Overview of DOT GPS Adjacent Band Compatibility Assessment Plan and plans/timeline for implementation. Presentation on GPS use cases and list of representative GPS receivers....

An overview of traffic monitoring programs in large urban areas

DOT National Transportation Integrated Search

2008-08-01

This report is intended to assist transportation and environmental professionals in the event of a bridge collapse or similar emergency. It analyzes the environmental review process in five cases of bridge reconstruction following collapse in Florida...

Nursing ethics in the seventh-day adventist religious tradition.

PubMed

Taylor, Elizabeth Johnston; Carr, Mark F

2009-11-01

Nurses' religious beliefs influence their motivations and perspectives, including their practice of ethics in nursing care. When the impact of these beliefs is not recognized, great potential for unethical nursing care exists. Thus, this article examines how the theology of one religious tradition, Seventh-day Adventism (SDA), could affect nurses. An overview of SDA history and beliefs is presented, which explains why 'medical missionary' work is central to SDAs. Theological foundations that would permeate an SDA nurse's view of the nursing metaparadigm concepts of person, health, environment (i.e. community), and nursing (i.e. service) are presented. The ethical principles guiding SDA nurses (i.e. principled, case-based, and care ethics) and the implications of these theological foundations for nurses are noted in a case study.

Epilepsy and videogames.

PubMed

Bureau, Michelle; Hirsch, Edouard; Vigevano, Federico

2004-01-01

Since the first case of videogame (VG) epilepsy was reported in 1981, many cases of seizures triggered by VGs were reported, not only in photosensitive, but also in non-photosensitive children and adolescents with epilepsy. We provide an overview of the literature with overall conclusions and recommendations regarding VG playing. Specific preventive measures concerning the physical characteristics of images included in commercially available VGs (flash rate, choice of colors, patterns, and contrast) can lead in the future to a clear decrease of this problem. In addition to the positive effect of such measures, the collaborative studies performed in France and in the rest of Europe have stressed the importance of a safe distance to the screen of > or = 2 m, and the less provocative role of 100-Hz screens.

Soil ecotoxicology in Brazil is taking its course.

PubMed

Niva, Cintia Carla; Niemeyer, Julia Carina; Júnior, Flávio Manoel Rodrigues Da Silva; Nunes, Maria Edna Tenório; De Sousa, Danilo Lourenço; Aragão, Clara Wandenkolck Silva; Sautter, Klaus Dieter; Espindola, Evaldo Gaeta; Sousa, José Paulo; Römbke, Jörg

2016-06-01

Soil ecotoxicology has been motivated by the increasing global awareness on environmental issues. Northern Hemisphere has been the main driver of this science branch; however, the number and quality of contributions from the Southern Hemisphere are increasing quickly. In this case study, Brazil is taken as an example of how soil ecotoxicology has developed over the last 30 years. It starts with a brief historical overview depicting the main events on soil ecotoxicology in the country. Following, an overview on the Brazilian legislation related to soil ecotoxicology is given, covering regulations with prospective focus, mainly on the registration of pesticides. Regulations with retrospective focus in contaminated areas are also given. Then, an outline of the actors in soil ecotoxicology and examples of prospective ecotoxicological studies performed with soil organisms and plants are given by stressor groups: pesticides, pharmaceuticals, metals, and residues. Experiences from retrospective studies, mainly looking at the assessment of industrial sites, are also covered. Emphasis is given on methodological aspects, pointing to needed actions, mainly regarding the different biotic and abiotic conditions of a tropical country. Finally, the last session discusses how soil ecotoxicology could be improved in methodological adaptations as well as legal requirements.

Neurotoxic effects of gasoline and gasoline constituents.

PubMed Central

Burbacher, T M

1993-01-01

This overview was developed as part of a symposium on noncancer end points of gasoline and key gasoline components. The specific components included are methyl tertiary butyl ether, ethyl tertiary butyl ether, tertiary amyl methyl ether, butadiene, benzene, xylene, toluene, methyl alcohol, and ethyl alcohol. The overview focuses on neurotoxic effects related to chronic low-level exposures. A few general conclusions and recommendations can be made based on the results of the studies to date. a) All the compounds reviewed are neuroactive and, as such, should be examined for their neurotoxicity. b) For most of the compounds, there is a substantial margin of safety between the current permissible exposure levels and levels that would be expected to cause overt signs of neurotoxicity in humans. This is not the case for xylene, toluene, and methanol, however, where neurologic effects are observed at or below the current Threshold Limit Value. c) For most of the compounds, the relationship between chronic low-level exposure and subtle neurotoxic effects has not been studied. Studies therefore should focus on examining the dose-response relationship between chronic low-level exposure and subtle changes in central nervous system function. PMID:8020437

Munchausen syndrome by proxy presented as recurrent respiratory arrest and thigh abscess: a case study and overview.

PubMed

Foto Özdemir, Dilşad; Yalçın, Sıdıka Songül; Zeki, Ayşe; Yurdakök, Kadriye; Özusta, Şeniz; Köse, Aslıhan; Karadağ, Ferda; Yıldız, Irem; Balseven Odabaşı, Aysun; Kale, Gülsev

2013-01-01

While many physicians are familiar with the sexual or physical abuse of children, there is little awareness about Munchausen syndrome by proxy (MSBP). As case reports of MSBP increase, awareness among physicians is thought to increase as well. We thus present herein a 16-month-old girl who admitted to Hacettepe University İhsan Doğramacı Children's Hospital with the complaint of seizure, recurrent apnea and thigh abscess, who was later diagnosed as MSBP. The case was being followed by the Child Protection Team of the hospital (Haceteppe University Child Protection Unit [HU-CPU]). HU-CPU contributed to the early detection of this case and protected the child from a possible fatal outcome. The mother was confronted for MSBP and refused to take responsibility for her child's symptoms. As seen in this case, when MSBP is suspected, psychiatric evaluation of the mother, evaluation of the mother-child interaction and collection of a detailed family and social history can have a positive impact on the prognosis in these cases. This case report underlines the importance of multidisciplinary team work to share the responsibility and reduce the burden during the treatment process of these difficult and complicated cases.

Methodological Approaches in Conducting Overviews: Current State in HTA Agencies

ERIC Educational Resources Information Center

Pieper, Dawid; Antoine, Sunya-Lee; Morfeld, Jana-Carina; Mathes, Tim; Eikermann, Michaela

2014-01-01

Objectives: Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in…

Integration of Optimal Scheduling with Case-Based Planning.

DTIC Science & Technology

1995-08-01

integrates Case-Based Reasoning (CBR) and Rule-Based Reasoning (RBR) systems. ’ Tachyon : A Constraint-Based Temporal Reasoning Model and Its...Implementation’ provides an overview of the Tachyon temporal’s reasoning system and discusses its possible applications. ’Dual-Use Applications of Tachyon : From...Force Structure Modeling to Manufacturing Scheduling’ discusses the application of Tachyon to real world problems, specifically military force deployment and manufacturing scheduling.

Human reproductive cloning and related techniques: an overview of the legal environment and practitioner attitudes.

PubMed

Katayama, A

2001-08-01

This study provides an overview of the legal environment and assisted reproductive technology (ART) practitioner attitudes toward human reproductive cloning. A review of the law and a survey of ART practitioners and a comparison group of attorneys were undertaken. Human reproductive cloning has been prohibited in many countries, and may soon be prohibited in others. However, many ART practitioners support its use for limited indications. ART practitioners were surveyed concerning their views on human reproductive cloning and related techniques. A few had considered using or had used embryo splitting or germ cell nuclear transfer. Although they expressed some concerns about the present risk of reproductive cloning, most indicated that it did not violate their religious beliefs. More than three-quarters of ART practitioners responding indicated that they would be willing to provide human reproductive cloning in indicated cases if it were legally permissible to do so. A significant percentage of the group also indicated that they currently have the ability to provide this service.

Progress in bipolar disorder drug design toward the development of novel therapeutic targets: a clinician's perspective.

PubMed

Fornaro, Michele; Kardash, Lubna; Novello, Stefano; Fusco, Andrea; Anastasia, Annalisa; De Berardis, Domenico; Perna, Giampaolo; Carta, Mauro Giovanni

2018-03-01

Bipolar disorder (BD) is a considerable burden to the affected individual. The need for novel drug targets and improved drug design (DD) in BD is therefore clear. Areas covered: The following article provides a brief, narrative, clinician-oriented overview of the most promising novel pharmacological targets for BD along with a concise overview regarding the general DD process and the unmet needs relevant to BD. Expert opinion: A number of novel potential drug targets have been investigated. With the notable exception of the kynurenine pathway, available evidence is too scarce to highlight a definitive roadmap for forthcoming DD in BD. BD itself may present with different facets, as it is a polymorphic clinical spectrum. Therefore, promoting clinical-case stratification should be based on precision medicine, rather than on novel biological targets. Furthermore, the full release of raw study data to the scientific community and the development of uniform clinical trial standards (including more realistic outcomes) should be promoted to facilitate the DD process in BD.

Forensic psychiatric evaluations: an overview of methods, ethical issues, and criminal and civil assessments.

PubMed

Sher, Leo

2015-05-01

Forensic psychiatry is frequently defined as the branch of psychiatry that deals with issues arising in the interface between psychiatry and the law. Psychiatrists are called on by the legal system to provide testimony in a wide variety of cases, criminal and civil. In criminal cases, forensic psychiatrists may be asked to comment on the competence of a person to make decisions throughout all the phases of criminal investigation, trial, and punishment. These include the competence to stand trial, to plead guilty, to be sentenced, to waive appeal, and to be executed. In civil cases, forensic psychiatric experts are asked to evaluate a number of civil competences, including competence to make a will or contract or to make decisions about one's person and property. Psychiatrists are also called on to testify about many other issues related to civil cases. Forensic psychiatrists who work with children and adolescents are frequently involved in evaluations and testimonies concerning juvenile delinquency, child custody, termination of parental rights, and other issues. As such, forensic psychiatric experts have now developed into a reputable and well-known group of professionals. Forensic evaluation methods, ethical issues related to forensic psychiatric practice, and some common criminal and civil forensic psychiatric evaluations are discussed in this overview.

Tort and the Teacher: Some Considerations.

ERIC Educational Resources Information Center

Hammes, Richard P.

1979-01-01

This article provides teachers with an overview on tort liability as it applies to their profession, especially in relation to student injuries. Such legal concepts as tort, negligence, and in loco parentis are discussed and guidelines are drawn from selected court cases. (SJL)

Analysis of FMCSA Civil Penalty Enforcement Cases, 2010–14.

DOT National Transportation Integrated Search

2016-11-01

This report provides an overview of the civil penalty process and an analysis of the Federal Motor Carrier Safety Administrations (FMCSAs) civil penalty data from January 2010 through December 2014, in terms of claimed, settled, and paid dollar...

Recent Developments in the Law.

ERIC Educational Resources Information Center

Journal of Law and Education, 1983

1983-01-01

An overview of recent court decisions on prayer in public schools is followed by brief synopses of cases in nine areas concerning primary and secondary levels and four areas concerning higher education. Finally, law review articles on federal and state issues are summarized. (MD)

Benzene exposure in the petroleum distribution industry associated with leukemia in the United Kingdom: overview of the methodology of a case-control study.

PubMed Central

Rushton, L

1996-01-01

This paper describes basic principles underlying the methodology for obtaining quantitative estimates of benzene exposure in the petroleum marketing and distribution industry. Work histories for 91 cases of leukemia and 364 matched controls (4 per case) identified for a cohort of oil distribution workers up to the end of 1992 were obtained, primarily from personnel records. Information on the distribution sites, more than 90% of which were closed at the time of data collection, was obtained from site visits and archive material. Industrial hygiene measurements measured under known conditions were assembled for different tasks. These were adjusted for conditions where measured data were not available using variables known to influence exposure, such as temperature, technology, percentage of benzene in fuel handled, products handled, number of loads, and job activity. A quantitative estimate of dermal contact and peak exposure was also made. PMID:9118922

Advanced information processing system: Fault injection study and results

NASA Technical Reports Server (NTRS)

Burkhardt, Laura F.; Masotto, Thomas K.; Lala, Jaynarayan H.

1992-01-01

The objective of the AIPS program is to achieve a validated fault tolerant distributed computer system. The goals of the AIPS fault injection study were: (1) to present the fault injection study components addressing the AIPS validation objective; (2) to obtain feedback for fault removal from the design implementation; (3) to obtain statistical data regarding fault detection, isolation, and reconfiguration responses; and (4) to obtain data regarding the effects of faults on system performance. The parameters are described that must be varied to create a comprehensive set of fault injection tests, the subset of test cases selected, the test case measurements, and the test case execution. Both pin level hardware faults using a hardware fault injector and software injected memory mutations were used to test the system. An overview is provided of the hardware fault injector and the associated software used to carry out the experiments. Detailed specifications are given of fault and test results for the I/O Network and the AIPS Fault Tolerant Processor, respectively. The results are summarized and conclusions are given.

Kinematic and Hydrometer Data Products from Scanning Radars during MC3E

DOE Data Explorer

matthews, Alyssa; Dolan, Brenda; Rutledge, Steven

2016-02-29

Recently the Radar Meteorology Group at Colorado State University has completed major case studies of some top cases from MC3E including 25 April, 20 May and 23 May 2011. A discussion on the analysis methods as well as radar quality control methods is included. For each case, a brief overview is first provided. Then, multiple Doppler (using available X-SAPR and C-SAPR data) analyses are presented including statistics on vertical air motions, sub-divided by convective and stratiform precipitation. Mean profiles and CFAD's of vertical motion are included to facilitate comparison with ASR model simulations. Retrieved vertical motion has also been verified with vertically pointing profiler data. Finally for each case, hydrometeor types are included derived from polarimetric radar observations. The latter can be used to provide comparisons to model-generated hydrometeor fields. Instructions for accessing all the data fields are also included. The web page can be found at: http://radarmet.atmos.colostate.edu/mc3e/research/

Endocarditis due to Rhodotorula mucilaginosa in a kidney transplanted patient: case report and review of medical literature

PubMed Central

Cabral, Andrea Maria; da Siveira Rioja, Suzimar; Brito-Santos, Fabio; Peres da Silva, Juliana Ribeiro; MacDowell, Maria Luíza; Melhem, Marcia S. C.; Mattos-Guaraldi, Ana Luíza; Hirata Junior, Raphael

2017-01-01

Introduction. Endocarditis caused by yeasts is currently an emerging cause of infective endocarditis and, when accompanied byfever of unknown origin, is more severe since interferes with proper diagnosis and endocarditis treatment. Case presentation. The Rio de Janeiro Infective Endocarditis Study Group reports a case of infectious endocarditis (IE) with negative blood cultures in a 45-year-old white female resident in Rio de Janeiro, Brazil, previously submitted to kidney transplantation. After diagnosis and intervention, the valve culture revealed Rhodotorula mucilaginosa. The clinical aspects and overview of endocarditis caused by Rhodotorula spp. demonstrated that R. muscilaginosa have been isolated from the last IE cases from kidney transplanted patients. Conclusion. Though most of the patients (in literature) recovered well from endocarditis caused by Rhodotorula spp., physicians must be aware for diagnosis of fungemia and fungal treatment in kidney transplanted patients suffering of fever of unknown origin in the modern immunosuppressive treatment. PMID:29255609

Hepatitis E virus infection in Europe: surveillance and descriptive epidemiology of confirmed cases, 2005 to 2015.

PubMed

Aspinall, Esther J; Couturier, Elisabeth; Faber, Mirko; Said, Bengü; Ijaz, Samreen; Tavoschi, Lara; Takkinen, Johanna; Adlhoch, Cornelia

2017-06-29

Hepatitis E virus (HEV) is an under-recognised cause of acute hepatitis in high-income countries. The purpose of this study was to provide an overview of testing, diagnosis, surveillance activities, and data on confirmed cases in the European Union/European Economic Area (EU/EEA). A semi-structured survey was developed and sent to 31 EU/EEA countries in February 2016, 30 responded. Twenty of these countries reported that they have specific surveillance systems for HEV infection. Applied specific case definition for HEV infection varied widely across countries. The number of reported cases has increased from 514 cases per year in 2005 to 5,617 in 2015, with most infections being locally acquired. This increase could not be explained by additional countries implementing surveillance for HEV infections over time. Hospitalisations increased from less than 100 in 2005 to more than 1,100 in 2015 and 28 fatal cases were reported over the study period. EU/EEA countries are at different stages in their surveillance, testing schemes and policy response to the emergence of HEV infection in humans. The available data demonstrated a Europe-wide increase in cases. Standardised case definitions and testing policies would allow a better understanding of the epidemiology of HEV as an emerging cause of liver-related morbidity. This article is copyright of The Authors, 2017.

Coming to a town near you: corporate globalization and its impact on massachusetts workers.

PubMed

Mattera, Nancy Della; Gaudet, Jennifer

2002-01-01

This report examines five themes of globalization: trade agreements and job loss; corporate growth; outsourcing and privatization; downward wage pressures; and immigration. We begin with an overview that connects each of these themes to the Massachusetts experience and highlights the corporate strategies that are affecting this experience. These themes are then interwoven throughout the three case studies that follow: "forced supplier migration" at a GE supply plant in Wilmington; outsourced dining service workers at Harvard; and the transformation of the fish processing industry in New Bedford.

The economic value of remote sensing by satellite: An ERTS overview and the value of continuity of service. Volume 2: Source document

NASA Technical Reports Server (NTRS)

Andrews, J.; Donziger, A.; Hazelrigg, G. A., Jr.; Heiss, K. P.; Sand, F.; Stevenson, P.

1974-01-01

The economic value of an ERS system with a technical capability similar to ERTS, allowing for increased coverage obtained through the use of multiple active satellites in orbit is presented. A detailed breakdown of the benefits achievable from an ERS system is given and a methodology for their estimation is established. The ECON case studies in agriculture, water use, and land cover are described along with the current ERTS system. The cost for a projected ERS system is given.

Computer generated animation and movie production at LARC: A case study

NASA Technical Reports Server (NTRS)

Gates, R. L.; Matthews, C. G.; Vonofenheim, W. H.; Randall, D. P.; Jones, K. H.

1984-01-01

The process of producing computer generated 16mm movies using the MOVIE.BYU software package developed by Brigham Young University and the currently available hardware technology at the Langley Research Center is described. A general overview relates the procedures to a specific application. Details are provided which describe the data used, preparation of a storyboard, key frame generation, the actual animation, title generation, filming, and processing/developing the final product. Problems encountered in each of these areas are identified. Both hardware and software problems are discussed along with proposed solutions and recommendations.

A Case Study: Using Delmia at Kennedy Space Center to Support NASA's Constellation Program

NASA Technical Reports Server (NTRS)

Kickbusch, Tracey; Humeniuk, Bob

2010-01-01

The presentation examines the use of Delmia (Digital Enterprise Lean Manufacturing Interactive Application) for digital simulation in NASA's Constellation Program. Topics include an overview of the Kennedy Space Center (KSC) Design Visualization Group tasks, NASA's Constellation Program, Ares 1 ground processing preliminary design review, and challenges and how Delmia is used at KSC, Challenges include dealing with large data sets, creating and maintaining KSC's infrastructure, gathering customer requirements and meeting objectives, creating life-like simulations, and providing quick turn-around on varied products,

Evaluation of Navy Human Relations Training for Civilian and Military Supervisors and Managers - A Conceptual Framework and a Case Study

DTIC Science & Technology

1977-05-20

the knowledge of first- and second-line Navy civilian supervisors concerning the dynamics of sexism and racism , with implications for behavior...Identification of the problem ( sexism and racism )-Define what these things are, how they came to be, and what can be done about them. 2. Identification of...managers become reflected in the organization’s EEO statistics ; and an overview of the steps and procedures —Continued DD | j0R^3 1473 EDITION OF

Coding in Muscle Disease.

PubMed

Jones, Lyell K; Ney, John P

2016-12-01

Accurate coding is critically important for clinical practice and research. Ongoing changes to diagnostic and billing codes require the clinician to stay abreast of coding updates. Payment for health care services, data sets for health services research, and reporting for medical quality improvement all require accurate administrative coding. This article provides an overview of administrative coding for patients with muscle disease and includes a case-based review of diagnostic and Evaluation and Management (E/M) coding principles in patients with myopathy. Procedural coding for electrodiagnostic studies and neuromuscular ultrasound is also reviewed.

Overview of SPH-ALE applications for hydraulic turbines in ANDRITZ Hydro

NASA Astrophysics Data System (ADS)

Rentschler, M.; Marongiu, J. C.; Neuhauser, M.; Parkinson, E.

2018-02-01

Over the past 13 years, ANDRITZ Hydro has developed an in-house tool based on the SPH-ALE method for applications in flow simulations in hydraulic turbines. The initial motivation is related to the challenging simulation of free surface flows in Pelton turbines, where highly dynamic water jets interact with rotating buckets, creating thin water jets traveling inside the housing and possibly causing disturbances on the runner. The present paper proposes an overview of industrial applications allowed by the developed tool, including design evaluation of Pelton runners and casings, transient operation of Pelton units and free surface flows in hydraulic structures.

40 CFR 86.527-90 - Test procedures, overview.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Section 86.527-90 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... constant volume (variable dilution) sampler. (d) Except in cases of component malfunction or failure, all... emissions measurements are made. For exhaust testing, this requires sampling and analysis of the dilution...

Discrimination in Public Employment: The Evolving Law.

ERIC Educational Resources Information Center

McCarthy, Martha M.

This monograph reviews the current status of constitutional, statutory, and case law governing public employers' obligations to assure equal employment opportunities and employees' rights to nondiscriminatory treatment. An initial overview of the legal framework discusses federal equal protection mandates including the guarantee of equal…

Risk assessment as standard work in design.

PubMed

Morrill, Patricia W

2013-01-01

This case study article examines a formal risk assessment as part of the decision making process for design solutions in high risk areas. The overview of the Failure Modes and Effects Analysis (FMEA) tool with examples of its application in hospital building projects will demonstrate the benefit of those structured conversations. This article illustrates how two hospitals used FMEA when integrating operational processes with building projects: (1) adjacency decision for Intensive Care Unit (ICU); and (2) distance concern for handling of specimens from Surgery to Lab. Both case studies involved interviews that exposed facility solution concerns. Just-in-time studies using the FMEA followed the same risk assessment process with the same workshop facilitator involving structured conversations in analyzing risks. In both cases, participants uncovered key areas of risk enabling them to take the necessary next steps. While the focus of this article is not the actual design solution, it is apparent that the risk assessment brought clarity to the situations resulting in prompt decision making about facility solutions. Hospitals are inherently risky environments; therefore, use of the formal risk assessment process, FMEA, is an opportunity for design professionals to apply more rigor to design decision making when facility solutions impact operations in high risk areas. Case study, decision making, hospital, infection control, strategy, work environment.

Space benefits: The secondary application of aerospace technology in other sectors of the economy

NASA Technical Reports Server (NTRS)

1976-01-01

A benefits briefing notebook is presented for the NASA Technology Utilization Office in which 515 applications of NASA aerospace technology to other sections of the economy are described. An overview of technology transfer is given. Benefit cases are cited in 19 categories along with pertinent information, such as communication link, DRI transfer example file, and individual case number. General, organization, geographic, and field center indexes are provided.

Overview of Medicaid capitation and case-management initiatives

PubMed Central

Freund, Deborah A.; Neuschler, Edward

1986-01-01

Case-management programs have grown in number and in acceptance in the Medicaid program since 1981. In this article, we review their structure and incentives as well as what is known about their impact on cost and use. These programs also have been difficult to implement, posing myriad management challenges for prepaid program managers and State administrators. We highlight the problems in the following areas: eligibility, enrollment, rate setting, and management information systems. PMID:10311923

Metagenetic tools for the census of marine meiofaunal biodiversity: An overview.

PubMed

Carugati, Laura; Corinaldesi, Cinzia; Dell'Anno, Antonio; Danovaro, Roberto

2015-12-01

Marine organisms belonging to meiofauna (size range: 20-500 μm) are amongst the most abundant and highly diversified metazoans on Earth including 22 over 35 known animal Phyla and accounting for more than 2/3 of the abundance of metazoan organisms. In any marine system, meiofauna play a key role in the functioning of the food webs and sustain important ecological processes. Estimates of meiofaunal biodiversity have been so far almost exclusively based on morphological analyses, but the very small size of these organisms and, in some cases, the insufficient morphological distinctive features limit considerably the census of the biodiversity of this component. Molecular approaches recently applied also to small invertebrates (including meiofauna) can offer a new momentum for the census of meiofaunal biodiversity. Here, we provide an overview on the application of metagenetic approaches based on the use of next generation sequencing platforms to study meiofaunal biodiversity, with a special focus on marine nematodes. Our overview shows that, although such approaches can represent a useful tool for the census of meiofaunal biodiversity, there are still different shortcomings and pitfalls that prevent their extensive use without the support of the classical taxonomic identification. Future investigations are needed to address these problems and to provide a good match between the contrasting findings emerging from classical taxonomic and molecular/bioinformatic tools. Copyright © 2015. Published by Elsevier B.V.

Seal Technology for Hypersonic Vehicle and Propulsion: An Overview

NASA Technical Reports Server (NTRS)

Steinetz, Bruce M.

2008-01-01

Hypersonic vehicles and propulsion systems pose an extraordinary challenge for structures and materials. Airframes and engines require lightweight, high-temperature materials and structural configurations that can withstand the extreme environment of hypersonic flight. Some of the challenges posed include very high temperatures, heating of the whole vehicle, steady-state and transient localized heating from shock waves, high aerodynamic loads, high fluctuating pressure loads, potential for severe flutter, vibration, and acoustic loads and erosion. Correspondingly high temperature seals are required to meet these aggressive requirements. This presentation reviews relevant seal technology for both heritage (e.g. Space Shuttle, X-15, and X-38) vehicles and presents several seal case studies aimed at providing lessons learned for future hypersonic vehicle seal development. This presentation also reviews seal technology developed for the National Aerospace Plane propulsion systems and presents several seal case studies aimed at providing lessons learned for future hypersonic propulsion seal development.

The Potential and Limitations of Cross-Context Comparative Research on Migration

PubMed Central

Riosmena, Fernando

2017-01-01

This article is an overview of household survey approaches for the comparative study of international migration dynamics. Focusing on differences in the drivers of international mobility at different times and places, I highlight the problems of obtaining data with adequate representation across time periods and geographies, and discuss a broad constellation of prospective and retrospective approaches, paying particular attention to the migration ethnosurvey. I place this methodology within a broader constellation of prospective and retrospective data collection techniques, briefly describing the advantages and disadvantages of each and summarizing the commonalities and differences of ethnosurvey approaches adopted around the world. In particular, I discuss the potential and limitations of cross-context research and suggest post hoc case selection and other adjustments to ameliorate problems. I conclude with ideas about how case and sample selection can help to bolster migration studies in the future. PMID:29093598

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.

PubMed

Lilljebjörn, Henrik; Henningsson, Rasmus; Hyrenius-Wittsten, Axel; Olsson, Linda; Orsmark-Pietras, Christina; von Palffy, Sofia; Askmyr, Maria; Rissler, Marianne; Schrappe, Martin; Cario, Gunnar; Castor, Anders; Pronk, Cornelis J H; Behrendtz, Mikael; Mitelman, Felix; Johansson, Bertil; Paulsson, Kajsa; Andersson, Anna K; Fontes, Magnus; Fioretos, Thoas

2016-06-06

Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 paediatric B-cell precursor acute lymphoblastic leukaemia (BCP ALL). Using RNA sequencing, we find in-frame fusion genes in 127 (65%) cases, including 27 novel fusions. We describe a subtype characterized by recurrent IGH-DUX4 or ERG-DUX4 fusions, representing 4% of cases, leading to overexpression of DUX4 and frequently co-occurring with intragenic ERG deletions. Furthermore, we identify a subtype characterized by an ETV6-RUNX1-like gene-expression profile and coexisting ETV6 and IKZF1 alterations. Thus, this study provides a detailed overview of fusion genes in paediatric BCP ALL and adds new pathogenetic insights, which may improve risk stratification and provide therapeutic options for this disease.

Mapping Indigenous land management for threatened species conservation: An Australian case-study.

PubMed

Renwick, Anna R; Robinson, Catherine J; Garnett, Stephen T; Leiper, Ian; Possingham, Hugh P; Carwardine, Josie

2017-01-01

Much biodiversity lives on lands to which Indigenous people retain strong legal and management rights. However this is rarely quantified. Here we provide the first quantitative overview of the importance of Indigenous land for a critical and vulnerable part of biodiversity, threatened species, using the continent of Australia as a case study. We find that three quarters of Australia's 272 terrestrial or freshwater vertebrate species listed as threatened under national legislation have projected ranges that overlap Indigenous lands. On average this overlap represents 45% of the range of each threatened species while Indigenous land is 52% of the country. Hotspots where multiple threatened species ranges overlap occur predominantly in coastal Northern Australia. Our analysis quantifies the vast potential of Indigenous land in Australia for contributing to national level conservation goals, and identifies the main land management arrangements available to Indigenous people which may enable them to deliver those goals should they choose to do so.

What guidance is available for researchers conducting overviews of reviews of healthcare interventions? A scoping review and qualitative metasummary.

PubMed

Pollock, Michelle; Fernandes, Ricardo M; Becker, Lorne A; Featherstone, Robin; Hartling, Lisa

2016-11-14

Overviews of reviews (overviews) compile data from multiple systematic reviews to provide a single synthesis of relevant evidence for decision-making. Despite their increasing popularity, there is limited methodological guidance available for researchers wishing to conduct overviews. The objective of this scoping review is to identify and collate all published and unpublished documents containing guidance for conducting overviews examining the efficacy, effectiveness, and/or safety of healthcare interventions. Our aims were to provide a map of existing guidance documents; identify similarities, differences, and gaps in the guidance contained within these documents; and identify common challenges involved in conducting overviews. We conducted an iterative and extensive search to ensure breadth and comprehensiveness of coverage. The search involved reference tracking, database and web searches (MEDLINE, EMBASE, DARE, Scopus, Cochrane Methods Studies Database, Google Scholar), handsearching of websites and conference proceedings, and contacting overview producers. Relevant guidance statements and challenges encountered were extracted, edited, grouped, abstracted, and presented using a qualitative metasummary approach. We identified 52 guidance documents produced by 19 research groups. Relatively consistent guidance was available for the first stages of the overview process (deciding when and why to conduct an overview, specifying the scope, and searching for and including systematic reviews). In contrast, there was limited or conflicting guidance for the latter stages of the overview process (quality assessment of systematic reviews and their primary studies, collecting and analyzing data, and assessing quality of evidence), and many of the challenges identified were also related to these stages. An additional, overarching challenge identified was that overviews are limited by the methods, reporting, and coverage of their included systematic reviews. This compilation of methodological guidance for conducting overviews of healthcare interventions will facilitate the production of future overviews and can help authors address key challenges they are likely to encounter. The results of this project have been used to identify areas where future methodological research is required to generate empirical evidence for overview methods. Additionally, these results have been used to update the chapter on overviews in the next edition of the Cochrane Handbook for Systematic Reviews of Interventions.

Overview of reviews in child health: evidence synthesis and the knowledge base for a specific population.

PubMed

Thomson, Denise; Foisy, Michelle; Oleszczuk, Marta; Wingert, Aireen; Chisholm, Annabritt; Hartling, Lisa

2013-01-01

Overviews of reviews are an evolving form of evidence synthesis. The Cochrane Child Health Field has been producing overviews since 2006, during which time the methods that have been used have changed, both due to the development of guidance within The Cochrane Collaboration and to the decisions made by individual author teams. This paper studies the first 29 overviews published in EBCH. To describe some aspects of the approaches taken in EBCH overviews to producing evidence syntheses relevant to the healthcare needs of children; to highlight the contribution that overviews can make to the knowledge base for treatment for a particular population. Data was extracted on: whether the overview included systematic review (SR) data only, or also data from individual trials not present in the included SRs; name(s) of the Cochrane Review Group (CRG) that prepared the included SRs; topics of the overviews as compared to the topics of the included reviews; age-subgroup analyses presented in the overviews. In 23 overviews, all published in 2012, the authors included trial data as well as SR data; two overviews addressed conditions not explicitly addressed by the included reviews; three overviews included pre-specified age-subgroup analyses. The aim of clinical relevance has been achieved by means such as: drawing from reviews produced by multiple CRGs; using SR evidence to explore clinically relevant topics that may not match exactly with the topics covered by the SRs; ensuring that the evidence in overviews is as up to date as possible by redoing searches and including trials not incorporated in the included SRs; and, where permitted by the data, using age-subgroup analyses to present the data in a way which matches the stages of childhood development. Overview authors are dependent on the nature of the data and methods reported in the included SRs. This suggests a need for further study about how SRs could be conducted in order to facilitate the conduct of overviews. Copyright © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

The Legal Context of Sexual Harassment in Education.

ERIC Educational Resources Information Center

Shoop, Robert J.

1998-01-01

Discusses legal aspects of sexual harassment in educational settings: definitions, the central issue of impact on the educational environment, questions about consensual sexual relationships, the concept of welcomeness, rights of the accused, issues of academic freedom, and successful defenses. Overviews relevant legislation, court cases,…

National Earthquake Information Center systems overview and integration

USGS Publications Warehouse

Guy, Michelle R.; Patton, John M.; Fee, Jeremy; Hearne, Mike; Martinez, Eric; Ketchum, D.; Worden, Charles; Quitoriano, Vince; Hunter, Edward; Smoczyk, Gregory; Schwarz, Stan

2015-08-18

It is important to note that this document provides a brief introduction to the work of dozens of software developers and IT specialists, spanning in many cases more than a decade. References to significant amounts of supporting documentation, code, and information are supplied within.

Examples of EOS Variables as compared to the UMM-Var Data Model

NASA Technical Reports Server (NTRS)

Cantrell, Simon; Lynnes, Chris

2016-01-01

In effort to provide EOSDIS clients a way to discover and use variable data from different providers, a Unified Metadata Model for Variables is being created. This presentation gives an overview of the model and use cases we are handling.

Recap and Program Plan Update [GPS Adjacent Band Compatibility Assessment Workshop IV RTCA - Washington, DC

DOT National Transportation Integrated Search

2015-10-02

Initial WorkshopI held on September 18, 2014 at the Volpe Center; Overview of DOT GPS Adjacent Band Compatibility Assessment Plan and plans/timeline for implementation; Presentation on GPS use cases and list of representative GPS receivers; Descri...

From the Stadium Parking Lot to the Information Superhighway: How To Protect Your Trademarks from Infringement.

ERIC Educational Resources Information Center

Bearby, Scott; Siegal, Bruce

2002-01-01

Provides an overview of collegiate trademark cases; discusses several forms of infringement, including traditional infringement on commercial products, ambush marketing, and Internet infringement; addresses available remedies; and offers practical tips for dealing effectively with trademark protection. (EV)

Employees.

ERIC Educational Resources Information Center

Jones, Thomas N.

The purpose of this chapter is to offer an overview and analysis of all the cases rendered during 1980 concerning the legal parameters of employment issues in institutions of higher education. Judicial review of employment decisions encompassed a broad range of actions, including selection and appointment; dismissal and nonrenewal; the termination…

The Flipped Classroom in Counselor Education

ERIC Educational Resources Information Center

Moran, Kristen; Milsom, Amy

2015-01-01

The flipped classroom is proposed as an effective instructional approach in counselor education. An overview of the flipped-classroom approach, including advantages and disadvantages, is provided. A case example illustrates how the flipped classroom can be applied in counselor education. Recommendations for implementing or researching flipped…

Effects of the Atmosphere on the Propagation of 10.6-micro Laser Beams.

PubMed

Hayes, J N; Ulrich, P B; Aitken, A H

1972-02-01

This paper gives an overview of the use of a wave optics computer code to model the propagation of high power CO(2) laser beams in the atmosphere. The nonlinear effects of atmospheric heating and kinetic cooling phenomena are included in the analysis. Only steady-state, nonturbulent cases are studied. Thermal conduction and free convection are assumed negligible compared to other effects included in the calculation. Results showing the important effect of water vapor concentration on beam quality are given. Beam slewing is also studied. Comparison is made with geometrical optics results, and good agreement is found with laboratory experiments that simulate atmospheric propagation.

Material characterisation with methods of nonlinear optics

NASA Astrophysics Data System (ADS)

Prylepa, A.; Reitböck, C.; Cobet, M.; Jesacher, A.; Jin, X.; Adelung, R.; Schatzl-Linder, M.; Luckeneder, G.; Stellnberger, K.-H.; Steck, T.; Faderl, J.; Stehrer, T.; Stifter, D.

2018-01-01

In this review, we present nonlinear optical methods, based on the second and third order nonlinear polarization, especially in the context of material characterization tasks outside the area of life sciences—for which these techniques are mostly designed. An overview of application studies reported to date is given, together with a discussion on the advantages and limits of the individual methods. Furthermore, new ways of experimentally combining different optical concepts are introduced, and their potential for characterisation and inspection tasks is evaluated in the context of various case studies, including the investigation of semiconductor surfaces, metals and related corrosion products, as well as of organic materials.

Accessible Near-Earth Objects (NEOs)

NASA Technical Reports Server (NTRS)

Barbee, Brent W.

2015-01-01

Near Earth Objects (NEOs) are asteroids and comets whose orbits are in close proximity to Earth's orbit; specifically, they have perihelia less than 1.3 astronomical units. NEOs particularly near Earth asteroids (NEAs) are identified as potential destinations for future human exploration missions. In this presentation I provide an overview of the current state of knowledge regarding the astrodynamical accessibility of NEAs according to NASA's Near Earth Object Human Space Flight Accessible Targets Study (NHATS). I also investigate the extremes of NEA accessibility using case studies and illuminate the fact that a space-based survey for NEOs is essential to expanding the set of known accessible NEAs for future human exploration missions.

How to deal with bone exposure and osteomyelitis: an overview.

PubMed

Verhelle, Nicolas; Van Zele, Dirk; Liboutton, Laurent; Heymans, Olivier

2003-12-01

The authors present an overview of the various techniques which can be used to achieve coverage of exposed bone, particularly in cases of bone exposure associated with an underlying fracture or osteomyelitis. Adequate debridement, possibly in several stages, is necessary in all cases to prepare the receptor site for the next step which is soft tissue coverage, achieved using various types of surgical procedures. Adequate reconstruction can be achieved with pedicled flaps in some cases but in cases with exposure of bone, free flaps usually represent a better option in cases where the condition of the patient is not a limiting factor. Thin fascio-cutaneous free flaps may be used in some cases with small and simple soft tissue loss, so as to minimise donor site mobidity. Free muscle flaps, such as from the latissimus dorsi, are preferable in cases with bone loss in order to fill any dead space; in cases with major bone loss, a free vascularised bone graft can be used, or composite grafts including bone, muscle and/or skin (fibula or crista iliaca flaps). Some reconstructions require a functional approach, such as over an exposed joint, or for the weight-bearing area of the foot or the soft tissues over the Achilles tendon. Survival of a free flap requires perfect, permeable microsutures; thrombosis of the anastomosis is a major complication which jeopardizes flap survival; close surveillance of the flap is required during the first few days, with hourly Doppler monitoring of the pedicle on the first day. The success rate can be as high as 90 to 100% in simple cases; failures may be related to surgical technique, inadequate choice of the flap, or specific features of the patient. In cases with an underlying bone infection, recurrence of infection occurs in 5 to 20% of cases; this requires additional treatment, possibly with repeat debridement, prolonged antibiotic therapy and sometimes a second free flap.

An Overview of the Percutaneous Antibiotic Delivery Technique for Osteomyelitis Treatment and a Case Study of Calcaneal Osteomyelitis.

PubMed

Karr, Jeffrey C

2017-11-01

A percutaneous antibiotic delivery technique (PAD-T) used for the adjunctive management of osteomyelitis is presented. This surgical technique incorporates a calcium sulfate and hydroxyapatite (calcium phosphate) bone void filler acting as a carrier vehicle with either an antibiotic or an antifungal medicine, delivering this combination directly into the area of osteomyelitis. The benefit of the PAD-T is reviewed with a case presentation of a successfully treated calcaneal osteomyelitis. No previously reported PAD-T using a simple bone cortex incision in the adjunctive treatment of osteomyelitis has been reported. The PAD-T safely and effectively uses a calcium sulfate and hydroxyapatite bone void filler carrier vehicle to deliver either an antibiotic or an antifungal medicine directly into the area of osteomyelitis.

Approaches for assessing health risks from complex mixtures in indoor air: a panel overview.

PubMed Central

Henry, C J; Fishbein, L; Meggs, W J; Ashford, N A; Schulte, P A; Anderson, H; Osborne, J S; Sepkovic, D W

1991-01-01

Critical to a more definitive human health assessment of the potential health risks from exposure to complex mixtures in indoor air is the need for a more definitive clinical measure and etiology of the health effects of complex mixtures. This panel overview highlights six of the eight presentations of the conference panel discussion and features a number of the major topical areas of indoor air concern. W. G. Meggs assessed clinical research priorities with primary focus on the role of volatile organic chemicals in human health, recognizing the areas where definitive data are lacking. By recognizing many types of chemical sensitivity, it may be possible to design studies that can illuminate the mechanisms by which chemical exposure may cause disease. The critically important topic of multiple chemical sensitivity was discussed by N. A. Ashford, who identified four high risk groups and defined the demographics of these groups. P. A. Schulte addressed the issue of biological markers of susceptibility with specific considerations of both methodological and societal aspects that may be operative in the ability to detect innate or inborne differences between individuals and populations. Three case studies were reviewed. H. Anderson discussed the past and present priorities from a public health perspective, focusing on those issues dealing with exposures to environmental tobacco smoke and formaldehyde off-gassing from materials used in mobile home construction. J. J. Osborne described several case studies involving wood smoke exposure to children, with emphasis on the significantly greater occurrence of chronic respiratory symptoms and acute chest illness for children from homes heated with woodburning stoves.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1821367

The ethics of contacting family members of a subject in a genetic research study to return results for an autosomal dominant syndrome.

PubMed

Taylor, Holly A; Wilfond, Benjamin S

2013-01-01

This case explores the ethical landscape around recontacting a subject's relatives to return genetic research results when the informed consent form signed by the original cohort of subjects is silent on whether investigators may share new information with the research subject's family. As a result of rapid advances in genetic technology, methods to identify genetic markers can mature during the life course of a study. In this case, the investigators identified the genetic mutation responsible for the disorder after a number of their original subjects had died. The researchers now have the ability to inform relatives of the subject about their risk of developing the same disease. Mark Rothstein, JD, from the University of Louisville School of Medicine, provides an overview of the medical/scientific, legal, and ethical issues underlying this case. Lauren Milner, PhD, and colleagues at Stanford University explore how the relationship between researcher and subject affect this debate. Seema Shah, JD, and colleagues at the National Institutes of Health and University of California, Los Angeles (UCLA) discuss whether and how requirements of the duty to warn are applicable in this case.

The taxation of unhealthy energy-dense foods (EDFs) and sugar-sweetened beverages (SSBs): An overview of patterns observed in the policy content and policy context of 13 case studies.

PubMed

Hagenaars, Luc Louis; Jeurissen, Patrick Paulus Theodoor; Klazinga, Niek Sieds

2017-08-01

Taxation of energy-dense foods (EDFs) and sugar-sweetened beverages (SSBs) is increasingly of interest as a novel public health and fiscal policy instrument. However academic interest in policy determinants has remained limited. We address this paucity by comparing the policy content and policy context of EDF/SSB taxes witnessed in 13 case studies, of which we assume the tax is sufficiently high to induce behavioural change. The observational and non-randomized studies published on our case studies seem to indicate that the EDF/SSB taxes under investigation generally had the desired effects on prices and consumption of targeted products. The revenue collection of EDF/SSB taxes is minimal yet significant. Administrative practicalities in tax levying are important, possibly explaining why a drift towards solely taxing SSBs can be noted, as these can be demarcated more easily, with levies seemingly increasing in more recent case studies. Despite the growing body of evidence suggesting that EDF/SSB taxes have the potential to improve health, fiscal needs more often seem to lay their policy foundation rather than public health advocacy. A remarkable amount of conservative/liberal governments have adopted these taxes, although in many cases revenues are earmarked for benefits compensating regressive income effects. Governments voice diverse policy rationales, ranging from explicitly describing the tax as a public health instrument, to solely explicating revenue raising. Copyright © 2017 Elsevier B.V. All rights reserved.

Legal Issues in Terminating Tenured Faculty Members Because of Financial Exigency.

ERIC Educational Resources Information Center

Saunders, Marybeth K.

1984-01-01

An overview of recent court cases concerning dismissal of tenured college faculty for reasons of financial exigency focuses on court definitions of exigency, criteria for "just cause" for termination, due process requirements, reemployment, compensation for wrongful termination, and legal requirements that constitute "good…

OSATE Overview & Community Updates

DTIC Science & Technology

2015-02-15

update 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Delange /Julien 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...main language capabilities Modeling patterns & model samples for beginners Error-Model examples EMV2 model constructs Demonstration of tools Case

Legal Liabilities of Administrators.

ERIC Educational Resources Information Center

Underwood, Julie

This chapter of "Principles of School Business Management" discusses the implications of several court cases for legal issues affecting the role of the school business official. The issues addressed include civil rights, negligence, contracts, criminal liability, tuition and fees, and student records. The chapter opens with a brief overview of…

AN OVERVIEW OF COASTAL ENVIRONMENTAL HEALTH INDICATORS

EPA Science Inventory

Discussions of the coastal environment and its health can be improved by more precise use of terms and clarification of the relationship, if any, between the health of ecosystems and the risks to human health. Ecosystem health is seldom defined and, in any case, has to be regarde...

Seizure Disorders: An Alternative Explanation for Students' Inattention.

ERIC Educational Resources Information Center

Agnew, Christina M.; Nystul, Michael S.; Conner, Mary Catherine

1998-01-01

Provides an overview of seizure disorders. They are more common than previously thought, and most have their onset in adolescence. Types of seizure disorders common in children, their symptoms, and treatment are described. A case example illustrates behavior in school and a paradoxical medication effect. (EMK)

Technology, Disability, and Law: Then and Now

ERIC Educational Resources Information Center

Dalsen, Jennifer

2017-01-01

Disability law and technology services share a rich history. This article investigates this transformative relationship through the contextual framework of the Individuals with Disabilities Education Act. A summary of legal cases, accommodation services, and barriers to access are explored. This includes an overview of the challenges facing…

A literature review of blood concentrations of new psychoactive substances classified as phenethylamines, aminoindanes, arylalkylamines, arylcyclohexylamines, and indolalkylamines.

PubMed

Karinen, Ritva; Høiseth, Gudrun

2017-07-01

Interpretation of blood concentrations of new psychoactive substances (NPS) requires comparison of the results to previously published case reports; as only a few experimental studies for these substances exist. A large number of articles representing single or multiple cases have been published for a great number of substances, making a unified overview difficult. In this review we have collected all published blood concentrations from the NPS groups classified as phenethylamines, aminoindanes, arylalkylamines, arylcyclohexylamines, and indolalkylamines, and also included unpublished results for MPA, MXE, 4-FMA, 4-FA and 4-MA analyzed in our laboratory. In total, 71 publications on 35 different drugs were summarized. For most of the drugs, the total number of reported cases was very low (≤5). For some of the synthetic drugs, however, a higher number of blood concentrations are now available; especially for 5-IT (32 reported cases in total), MPA (31 reported cases in total) and MXE (36 reported cases in total), thus the published results are more substantial. The present compilation could be a helpful tool for forensic toxicologists when blood concentrations of NPS are assessed. Copyright © 2017. Published by Elsevier B.V.

The Case of the Great Space Exploration: An Educator Guide with Activities in Mathematics, Science, and Technology. The NASA SCI Files. EG-2004-09-12-LARC

ERIC Educational Resources Information Center

Ricles, Shannon; Jaramillo, Becky; Fargo, Michelle

2004-01-01

In this companion to the "NASA SCI Files" episode "The Case of the Great Space Exploration," the tree house detectives learn about NASA's new vision for exploring space. In four segments aimed at grades 3-5, students learn about a variety of aspects of space exploration. Each segment of the guide includes an overview, a set of objectives,…

Small bowel perforation: a rare complication of ventriculoperitoneal shunt placement

PubMed Central

Bourm, Kelsey; Pfeifer, Cory; Zarchan, Adam

2016-01-01

Small bowel perforation is a rare complication of ventriculoperitoneal (VP) shunt placement. When seen, it most commonly affects the stomach or colon. We describe a case and image findings of an 8-year-old female who presented with sepsis and erosion of the VP shunt into the small bowel. The imaging findings were confirmed surgically. We also provide an overview of the current literature discussing previously reported cases, clinical features, and treatment. PMID:27761183

The impact of demand management strategies on parents’ decision-making for out-of-hours primary care: findings from a survey in The Netherlands

PubMed Central

Giesen, Marie-Jeanne; Keizer, Ellen; van de Pol, Julia; Knoben, Joris; Wensing, Michel; Giesen, Paul

2017-01-01

Objective To explore the potential impact of demand management strategies on patient decision-making in medically non-urgent and urgent scenarios during out-of-hours for children between the ages of 0 and 4 years. Design and methods We conducted a cross-sectional survey with paper-based case scenarios. A survey was sent to all 797 parents of children aged between 0 and 4 years from four Dutch general practitioner (GP) practices. Four demand management strategies (copayment, online advice, overview medical cost and GP appointment next morning) were incorporated in two medically non-urgent and two urgent case scenarios. Combining the case scenarios with the demand management strategies resulted in 16 cases (four scenarios each with four demand management strategies). Each parent randomly received a questionnaire with three different case scenarios with three different demand strategies and a baseline case scenario without a demand management strategy. Results The response rate was 47.4%. The strategy online advice led to more medically appropriate decision-making for both non-urgent case scenarios (OR 0.26; 95% CI 0.11 to 0.58) and urgent case scenarios (OR 0.16; 95% CI 0.08 to 0.32). Overview of medical cost (OR 0.59; 95% CI 0.38 to 0.92) and a GP appointment planned the next morning (OR 0.57; 95% CI 0.34 to 0.97) had some influence on patient decisions for urgent cases, but not for non-urgent cases. Copayment had no influence on patient decisions. Conclusion Online advice has the highest potential to reduce medically unnecessary use. Furthermore it enhanced safety of parents' decisions on seeking help for their young children during out-of-hours primary care. Valid online information on health symptoms for patients should be promoted. PMID:28487458

The impact of demand management strategies on parents' decision-making for out-of-hours primary care: findings from a survey in The Netherlands.

PubMed

Giesen, Marie-Jeanne; Keizer, Ellen; van de Pol, Julia; Knoben, Joris; Wensing, Michel; Giesen, Paul

2017-05-09

To explore the potential impact of demand management strategies on patient decision-making in medically non-urgent and urgent scenarios during out-of-hours for children between the ages of 0 and 4 years. We conducted a cross-sectional survey with paper-based case scenarios. A survey was sent to all 797 parents of children aged between 0 and 4 years from four Dutch general practitioner (GP) practices. Four demand management strategies (copayment, online advice, overview medical cost and GP appointment next morning) were incorporated in two medically non-urgent and two urgent case scenarios. Combining the case scenarios with the demand management strategies resulted in 16 cases (four scenarios each with four demand management strategies). Each parent randomly received a questionnaire with three different case scenarios with three different demand strategies and a baseline case scenario without a demand management strategy. The response rate was 47.4%. The strategy online advice led to more medically appropriate decision-making for both non-urgent case scenarios (OR 0.26; CI 0.11 to 0.58) and urgent case scenarios (OR 0.16; CI 0.08 to 0.32). Overview of medical cost (OR 0.59; CI 0.38 to 0.92) and a GP appointment planned the next morning (OR 0.57; CI 0.34 to 0.97) had some influence on patient decisions for urgent cases, but not for non-urgent cases. Copayment had no influence on patient decisions. Online advice has the highest potential to reduce medically unnecessary use. Furthermore it enhanced safety of parents' decisions on seeking help for their young children during out-of-hours primary care. Valid online information on health symptoms for patients should be promoted. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

2011 Workplace and Equal Opportunity Survey of Reserve Component Members: Overview Report

DTIC Science & Technology

2014-02-06

2011 Workplace and Equal Opportunity Survey of Reserve Members Overview Report The estimated cost of report or study for the Department of...Ask for report by ADA602626 February 26, 2014 OVERVIEW REPORT Note No. 2013-003 1 2011 Workplace and Equal Opportunity Survey of Reserve...harassment and discrimination within the Reserve components. This overview report discusses findings from the 2011 Workplace and Equal Opportunity

The contribution of hospital library information services to clinical care: a study in eight hospitals.

PubMed Central

King, D N

1987-01-01

Hospital health sciences libraries represent, for the vast majority of health professionals, the most accessible source for library information and services. Most health professionals do not have available the specialized services of a clinical medical librarian, and rely instead upon general information services for their case-related information needs. The ability of the hospital library to meet these needs and the impact of the information on quality patient care have not been previously examined. A study was conducted in eight hospitals in the Chicago area as a quality assurance project. A total of 176 physicians, nurses, and other health professionals requested information from their hospital libraries related to a current case or clinical situation. They then assessed the quality of information received, its cognitive value, its contribution to patient care, and its impact on case management. Nearly two-thirds of the respondents asserted that they would definitely or probably handle their cases differently as a result of the information provided by the library. Almost all rated the libraries' performance and response highly. An overview of the context and purpose of the study, its methods, selected results, limitations, and conclusions are presented here, as is a review of selected earlier research. PMID:3450340

An overview of normal pressure hydrocephalus and its importance: how much do we really know?

PubMed

Siraj, Seema

2011-01-01

Normal pressure hydrocephalus (NPH) is a clinical triad of gait disturbance, dementia, and urinary incontinence combined with radiographic findings of ventriculomegaly and laboratory findings of normal cerebrospinal fluid pressures. Although it was first described by Hakim and Adams in 1965, there is no formal definition of NPH, causing discrepancy in its incidence in various studies. This ranges from 2 to 20 per million per year. It is estimated to be the cause of about 5% of cases of dementia and is one of the few reversible causes of dementia. Early diagnosis increases the rate of success to treatment. This makes accurate diagnosis and identification of responders to treatment important. There have been various studies on NPH in the general population, but not much has been said about it in long-term care facilities and the question arises on how many cases are missed. If a screening tool is in place to identify possible cases then further workup could be done to confirm the diagnosis and determine the need for shunting. Copyright © 2011 American Medical Directors Association. Published by Elsevier Inc. All rights reserved.

Is there still an unknown Freud? A note on the publications of Freud's texts and on unpublished documents.

PubMed

Falzeder, Ernst

2007-01-01

This article presents an overview of the existing editions of what Freud wrote (works, letters, manuscripts and drafts, diaries and calendar notes, dedications and margin notes in books, case notes, and patient calendars) and what he is recorded as having said (minutes of meetings, interviews, memoirs of and interviews with patients, family members, and followers, and other quotes). There follows a short overview of biographies of Freud and other documentation on his life. It is concluded that a wealth of material is now available to Freud scholars, although more often than not this information is used in a biased and partisan way.

Overview of mycotoxin methods, present status and future needs.

PubMed

Gilbert, J

1999-01-01

This article reviews current requirements for the analysis for mycotoxins in foods and identifies legislative as well as other factors that are driving development and validation of new methods. New regulatory limits for mycotoxins and analytical quality assurance requirements for laboratories to only use validated methods are seen as major factors driving developments. Three major classes of methods are identified which serve different purposes and can be categorized as screening, official and research. In each case the present status and future needs are assessed. In addition to an overview of trends in analytical methods, some other areas of analytical quality assurance such as participation in proficiency testing and reference materials are identified.

Brief Overview of a Decade of Genome-Wide Association Studies on Primary Hypertension.

PubMed

Azam, Afifah Binti; Azizan, Elena Aisha Binti

2018-01-01

Primary hypertension is widely believed to be a complex polygenic disorder with the manifestation influenced by the interactions of genomic and environmental factors making identification of susceptibility genes a major challenge. With major advancement in high-throughput genotyping technology, genome-wide association study (GWAS) has become a powerful tool for researchers studying genetically complex diseases. GWASs work through revealing links between DNA sequence variation and a disease or trait with biomedical importance. The human genome is a very long DNA sequence which consists of billions of nucleotides arranged in a unique way. A single base-pair change in the DNA sequence is known as a single nucleotide polymorphism (SNP). With the help of modern genotyping techniques such as chip-based genotyping arrays, thousands of SNPs can be genotyped easily. Large-scale GWASs, in which more than half a million of common SNPs are genotyped and analyzed for disease association in hundreds of thousands of cases and controls, have been broadly successful in identifying SNPs associated with heart diseases, diabetes, autoimmune diseases, and psychiatric disorders. It is however still debatable whether GWAS is the best approach for hypertension. The following is a brief overview on the outcomes of a decade of GWASs on primary hypertension.

Modeling zero-modified count and semicontinuous data in health services research Part 1: background and overview.

PubMed

Neelon, Brian; O'Malley, A James; Smith, Valerie A

2016-11-30

Health services data often contain a high proportion of zeros. In studies examining patient hospitalization rates, for instance, many patients will have no hospitalizations, resulting in a count of zero. When the number of zeros is greater or less than expected under a standard count model, the data are said to be zero modified relative to the standard model. A similar phenomenon arises with semicontinuous data, which are characterized by a spike at zero followed by a continuous distribution with positive support. When analyzing zero-modified count and semicontinuous data, flexible mixture distributions are often needed to accommodate both the excess zeros and the typically skewed distribution of nonzero values. Various models have been introduced over the past three decades to accommodate such data, including hurdle models, zero-inflated models, and two-part semicontinuous models. This tutorial describes recent modeling strategies for zero-modified count and semicontinuous data and highlights their role in health services research studies. Part 1 of the tutorial, presented here, provides a general overview of the topic. Part 2, appearing as a companion piece in this issue of Statistics in Medicine, discusses three case studies illustrating applications of the methods to health services research. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Overview of Seismic Hazard and Vulnerability of Ordinary Buildings in Belgium: Methodological Aspects and Study Cases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barszez, Anne-Marie; Camelbeeck, Thierry; Plumier, Andre

Northwest Europe is a region in which damaging earthquakes exist. Assessing the risks of damages is useful, but this is not an easy work based on exact science.In this paper, we propose a general tool for a first level assessment of seismic risks (rapid diagnosis). General methodological aspects are presented. For a given building, the risk is represented by a volume in a multi-dimensional space. This space is defined by axes representing the main parameters that have an influence on the risk. We notably express the importance of including a parameter to consider the specific value of cultural heritage.Then wemore » apply the proposed tool to analyze and compare methods of seismic risk assessment used in Belgium. They differ by the spatial scale of the studied area. Study cases for the whole Belgian Territory and for part of cities in Liege and Mons (Be) aim also to give some sense of the overall risk in Belgium.« less

CUBES: cassegrain U-band Brazil-ESO spectrograph

NASA Astrophysics Data System (ADS)

Barbuy, B.; Bawden Macanhan, V.; Bristow, P.; Castilho, B.; Dekker, H.; Delabre, B.; Diaz, M.; Gneiding, C.; Kerber, F.; Kuntschner, H.; La Mura, G.; Maciel, W.; Meléndez, J.; Pasquini, L.; Pereira, C. B.; Petitjean, P.; Reiss, R.; Siqueira-Mello, C.; Smiljanic, R.; Vernet, J.

2014-11-01

CUBES is a high-efficiency, medium-resolution ( R˜20,000) ground based UV (300-400 nm) spectrograph, to be installed in the cassegrain focus of one of ESO's VLT unit telescopes in 2017/18. The CUBES project is a joint venture between ESO and IAG/USP, and LNA/MCTI. CUBES will provide access to a wealth of new and relevant information for stellar as well as extragalactic sources. Main science cases include the study of beryllium and heavy elements in metal-poor stars, the direct determination of carbon, nitrogen and oxygen abundances by study of molecular bands in the UV range, as well as the study of active galactic nuclei and the quasar absorption lines. With a streamlined modern instrument design, high efficiency dispersing elements and UV-sensitive detectors, it will give a significant gain in sensitivity over existing ground based medium-high resolution spectrographs, enabling vastly increased sample sizes accessible to the astronomical community. We present here a brief overview of the project including the status, science cases and a discussion of the design options.

Modeling Signaling Networks to Advance New Cancer Therapies.

PubMed

Saez-Rodriguez, Julio; MacNamara, Aidan; Cook, Simon

2015-01-01

Cell signaling pathways control cells' responses to their environment through an intricate network of proteins and small molecules partitioned by intracellular structures, such as the cytoskeleton and nucleus. Our understanding of these pathways has been revised recently with the advent of more advanced experimental techniques; no longer are signaling pathways viewed as linear cascades of information flowing from membrane-bound receptors to the nucleus. Instead, such pathways must be understood in the context of networks, and studying such networks requires an integration of computational and experimental approaches. This understanding is becoming more important in designing novel therapies for diseases such as cancer. Using the MAPK (mitogen-activated protein kinase) and PI3K (class I phosphoinositide-3' kinase) pathways as case studies of cellular signaling, we give an overview of these pathways and their functions. We then describe, using a number of case studies, how computational modeling has aided in understanding these pathways' deregulation in cancer, and how such understanding can be used to optimally tailor current therapies or help design new therapies against cancer.

Delta Opioid Pharmacology in Relation to Alcohol Behaviors

PubMed Central

Alongkronrusmee, Doungkamol; Chiang, Terrance

2016-01-01

Delta opioid receptors (DORs) are heavily involved in alcohol-mediated processes in the brain. In this chapter we provide an overview of studies investigating how alcohol directly impacts DOR pharmacology and of early studies indicating DOR modulation of alcohol behavior. We will offer a brief summary of the different animal species used in alcohol studies investigating DORs followed by a broader overview of the types of alcohol behaviors modulated by DORs. We will highlight a small set of studies investigating the relationship between alcohol and DORs in analgesia. We will then provide an anatomical overview linking DOR expression in specific brain regions to different alcohol behaviors. In this section, we will provide two models that try to explain how endogenous opioids acting at DORs may influence alcohol behaviors. Next, we will provide an overview of studies investigating certain new aspects of DOR pharmacology, including the formation of heteromers and biased signaling. Finally, we provide a short overview of the genetics of the DORs in relation to alcohol use disorders (AUDs) and a short statement on the potential of using DOR-based therapeutics for treatment of AUDs. PMID:27316912

Choleperitoneum due to intrahepatic bile duct rupture - case report.

PubMed

Simion, L; Straja, Dn; Prunoiu, Vm; Alecu, M; Brătucu, E

2014-01-01

Non-traumatic perforations of the bile ducts are unfrequently encountered entities, all the more when they affect the intrahepatic bile ducts, exteriorizing their biliary content in the great peritoneal cavity. Reporting such a case has determined the authors to perform a careful overview of the cases present in the literature. An observation that can be made based on these is that the obstruction of the main bile duct due to lithiasis determines, by pressure increase, the dilation of the bile system branches, all on the background of an unknown malformation of the intrahepatic bile ducts. Celsius.

Applications of AN OO Methodology and Case to a Daq System

NASA Astrophysics Data System (ADS)

Bee, C. P.; Eshghi, S.; Jones, R.; Kolos, S.; Magherini, C.; Maidantchik, C.; Mapelli, L.; Mornacchi, G.; Niculescu, M.; Patel, A.; Prigent, D.; Spiwoks, R.; Soloviev, I.; Caprini, M.; Duval, P. Y.; Etienne, F.; Ferrato, D.; Le van Suu, A.; Qian, Z.; Gaponenko, I.; Merzliakov, Y.; Ambrosini, G.; Ferrari, R.; Fumagalli, G.; Polesello, G.

The RD13 project has evaluated the use of the Object Oriented Information Engineering (OOIE) method during the development of several software components connected to the DAQ system. The method is supported by a sophisticated commercial CASE tool (Object Management Workbench) and programming environment (Kappa) which covers the full life-cycle of the software including model simulation, code generation and application deployment. This paper gives an overview of the method, CASE tool, DAQ components which have been developed and we relate our experiences with the method and tool, its integration into our development environment and the spiral lifecycle it supports.

An unusual case of folliculitis spinulosa decalvans.

PubMed

Fan, Wenge; Zhang, Qingsong; Song, Linyi

2016-09-01

We report the case of a 24-year-old man who presented with pustules, atrophic scars, and alopecia on the scalp, along with follicular keratotic papules on the cheeks, chest, abdomen, back, lateral upper arms, thighs, and axillae, of 6 years' duration. A diagnosis of folliculitis spinulosa decalvans (FSD) was made based on the clinical manifestation and histopathological findings. Dental examination also revealed dental anomalies and a fissured tongue, which are not known to be related to FSD. We provide an overview of the characteristic findings of FSD as well as a review of previously reported cases.

A case management agency and bank create a service innovation.

PubMed

Katz, K S; Stowe, A W

1992-01-01

Connecticut Community Care, Inc. (CCCI), a statewide, nonprofit case management agency, in collaboration with Connecticut National Bank (CNB), developed a unique model of delivering case management services to bank trust clients. No reports of such a collaborative model have been found in the published literature in the United States. The article presents a historical overview of this innovative initiative; the identification of the target population; the delivery of the assessment, coordination, and monitoring services; and the marketing techniques. Utilization statistics, a synopsis of the model outcomes as viewed by the trust officers, and suggestions for replication are also presented.

Man-Machine Integrated Design and Analysis System (MIDAS): Functional Overview

NASA Technical Reports Server (NTRS)

Corker, Kevin; Neukom, Christian

1998-01-01

Included in the series of screen print-outs illustrates the structure and function of the Man-Machine Integrated Design and Analysis System (MIDAS). Views into the use of the system and editors are featured. The use-case in this set of graphs includes the development of a simulation scenario.

Preventive Law for School Administrators.

ERIC Educational Resources Information Center

Hawkins, Harold L.

This chapter focuses on the need for a revised relationship between schools and the courts through the concept of preventive law. The chapter reviews court cases and presents an overview of conflict resolution models and strategies for reducing litigation. Preventive law assumes that greater use of its strategies affords a lesser need for conflict…

Internationalizing Teacher Education: The Case of Belarus

ERIC Educational Resources Information Center

Lugovtsova, Alena; Krasnova, Tatiana; Torhova, Anna

2012-01-01

This article describes the unique characteristics of internationalization in teacher education in the Republic of Belarus, by asking how the creation of a national system of teacher education after the USSR's disintegration has both enhanced and hindered internationalization. The question is answered by providing an overview of the specific…

[Neurological diseases after lightning strike : Lightning strikes twice].

PubMed

Gruhn, K M; Knossalla, Frauke; Schwenkreis, Peter; Hamsen, Uwe; Schildhauer, Thomas A; Tegenthoff, Martin; Sczesny-Kaiser, Matthias

2016-06-01

Lightning strikes rarely occur but 85 % of patients have lightning-related neurological complications. This report provides an overview about different modes of energy transfer and neurological conditions related to lightning strikes. Moreover, two case reports demonstrate the importance of interdisciplinary treatment and the spectrum of neurological complications after lightning strikes.

Single-Subject Evaluation: A Tool for Quality Assurance.

ERIC Educational Resources Information Center

Nuehring, Elane M.; Pascone, Anne B.

1986-01-01

The use of single-subject designs in peer review, in utilization review, and in other quality-assurance audits is encouraged. Presents an overview of the methodologies of single-subject designs and quality assurance, and provides examples of cases in which single-subject techniques furnished relevant quality assurance documentation. (Author/ABB)

An Overview: The Crisis in Music Education.

ERIC Educational Resources Information Center

Prescott, Michael P.

1981-01-01

In this introductory article to a theme issue, the author discusses the impact of budget cuts, shrinking enrollment, the teacher's declining public image, and the fragmentation of the music industry and the music education field. On the positive side he describes two cases where community pressure prevented music program cuts. (SJL)

76 FR 5401 - Bureau of Justice Statistics; Agency Information Collection Activities: Proposed Collection...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-31

... collected will include the types of criminal cases appealed to state intermediate appellate courts and... notice of information collection under review: Survey of State Court Criminal Appeals, 2010. The... submission of responses. Overview of This Information (1) Type of information collection: New data collection...

76 FR 18581 - Agency Information Collection Activities: Proposed Collection; Comments Requested

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

... collected will include the types of criminal cases appealed to state intermediate appellate courts and... collection: Survey of State Court Criminal Appeals, 2010. The Department of Justice, Office of Justice... electronic submission of responses. Overview of This Information (1) Type of information collection: New data...

Literature-Based Instruction: Reshaping the Curriculum.

ERIC Educational Resources Information Center

Raphael, Taffy E., Ed.; Au, Kathryn H., Ed.

Making a case for the value of literature-based instruction, this book presents an overview of the extensive knowledge base supporting literature-based approaches to literacy instruction. It notes that literature-based instruction goes beyond simply changing the kinds of texts children read--also required in literature-based instruction are an…

Testing in Texas: Accountability for Bilingual Students.

ERIC Educational Resources Information Center

Porter, Rosalie Pedalino, Ed.

2000-01-01

This issue has a special, multi-article section on student testing in Texas and contains three additional and unrelated articles. "The Texas Testing Case Documents: G.I. Forum, et al. v. Texas Education Agency, et al." section has five articles: "Overview" (Roger Clegg); a copy of the "First Amended Complaint";…

Reduction-in-Force (RIF). A Legal Memorandum.

ERIC Educational Resources Information Center

Zirkel, Perry A.; Bargerstock, Charles T.

This legal memorandum provides an overview of the growing body of legislation and litigation concerning reduction in force (RIF). The focus of the article is the suspension or dismissal of teachers for reasons unrelated to their competence or behavior. Cases concerning other professional personnel such as principals, or other staffing strategies…

Youth and the Law: A Guide for Legislators.

ERIC Educational Resources Information Center

Minnesota House of Representatives, St. Paul. Research Dept.

This document describes Minnesota statutes and cases that provide rights, responsibilities, and protections for young people different from those applicable to adults. It gives legislators an overview of all laws affecting young people, serving as a reference aid for current state policies toward youth. It is basically a state guide, including…

Why CBI? An Examination of the Case for Computer-Based Instruction.

ERIC Educational Resources Information Center

Dean, Peter M.

1977-01-01

Discussion of the use of computers in instruction includes the relationship of theory to practice, the interactive nature of computer instruction, an overview of the Keller Plan, cost considerations, strategy for use of computers in instruction and training, and a look at examination procedure. (RAO)

76 FR 13137 - Equity Assistance Centers Program; Office of Elementary and Secondary Education; Overview...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-10

... uses multiple measures, that, in the case of teachers, may include observations for determining teacher...) training designed to improve the ability of teachers, supervisors, counselors, parents, community members... Effectiveness and Distribution of Effective Teachers or Principals. Projects that are designed to address the...

Utilizing Professional Learning Community Concepts and Social Networking for State Advocacy: The Arkansas Case

ERIC Educational Resources Information Center

Albritton, Shelly; Chadwick, Mona; Bangs, David; Holt, Carleton; Longing, Jeff; Duyar, Ibrihim

2016-01-01

This article provides an overview of National Council of Professors of Educational Administration (NCPEA) state affiliate, Arkansas Professors of Educational Administration's (ARPEA), activities, accomplishments, and advocacy efforts. Faced with numerous changes being implemented in education in the state, it became imperative for ARPEA's…

Special Education in Transition: Concepts to Guide the Education of Experienced Teachers.

ERIC Educational Resources Information Center

Corrigan, Dean C., Ed.; Howey, Kenneth R., Ed.

Eleven papers focus on issues in inservice education for helping experienced teachers accommodate handicapped children in the regular school setting. Two introductory chapters ("Overview" and "The School Based Teacher Educator: Developing a Conceptual Framework" both by K. Howey and D. Corrigan) make a case for developing a…

Special Education Program Evaluation: A Planning Guide. An Overview. CASE Commissioned Series.

ERIC Educational Resources Information Center

McLaughlin, John A.

This resource guide is intended to help in planning special education program evaluations. It focuses on: basic evaluation concepts, identification of special education decision makers and their information needs, specific evaluation questions, procedures for gathering relevant information, and evaluation of the evaluation process itself.…

Acousto-ultrasonics to Assess Material and Structural Properties

NASA Technical Reports Server (NTRS)

Kautz, Harold E.

2002-01-01

This report was created to serve as a manual for applying the Acousto-Ultrasonic NDE method, as practiced at NASA Glenn, to the study of materials and structures for a wide range of applications. Three state of the art acousto-ultrasonic (A-U) analysis parameters, ultrasonic decay (UD) rate, mean time (or skewing factor, "s"), and the centroid of the power spectrum, "f(sub c)," have been studied and applied at GRC for NDE interrogation of various materials and structures of aerospace interest. In addition to this, a unique application of Lamb wave analysis is shown. An appendix gives a brief overview of Lamb Wave analysis. This paper presents the analysis employed to calculate these parameters and the development and reasoning behind their use. It also discusses the planning of A-U measurements for materials and structures to be studied. Types of transducer coupling are discussed including contact and non-contact via laser and air. Experimental planning includes matching transducer frequency range to material and geometry of the specimen to be studied. The effect on results of initially zeroing the DC component of the ultrasonic waveform is compared with not doing so. A wide range of interrogation problems are addressed via the application of these analysis parameters to real specimens is shown for five cases: Case 1: Differences in density in [0] SiC/RBSN ceramic matrix composite. Case 2: Effect of tensile fatigue cycling in [+/-45] SiC/SiC ceramic matrix composite. Case 3: Detecting creep life, and failure, in Udimet 520 Nickel-Based Super Alloy. Case 4: Detecting Surface Layer Formation in T-650-35/PMR-15 Polymer Matrix Composites Panels due to Thermal Aging. Case 5: Detecting Spin Test Degradation in PMC Flywheels. Among these cases a wide range of materials and geometries are studied.

The properties of an ion selective enzymatic asymmetric synthetic membrane.

NASA Technical Reports Server (NTRS)

Mitz, M. A.

1971-01-01

With the aid of a simple model membrane system, the properties of cellulose enzymes and of membrane selectivity and pump-like action are considered. The model is based on materials possibly present on a primitive earth, as well as on a membrane able to sort or concentrate these materials. An overview of the model membrane system is presented in terms of how it is constructed, what its properties are, and what to expect in performance characteristics. The model system is shown to be useful for studying the selective and in some cases accelerated transfer of nutrients and metabolites.

Gratitude as a psychotherapeutic intervention.

PubMed

Emmons, Robert A; Stern, Robin

2013-08-01

Gratitude practice can be a catalyzing and relational healing force, often untapped in clinical practice. In this article, we provide an overview of current thinking about gratitude's defining and beneficial properties, followed by a brief review of the research on mental health outcomes that result from gratitude practice. Following an analysis of our case study of the use of gratitude as a psychotherapeutic intervention, we present various self-strategies and techniques for consciously choosing and cultivating gratitude. We conclude by describing ways in which gratitude might be capitalized upon for beneficial outcomes in therapeutic settings. © 2013 Wiley Periodicals, Inc.

Asian student migration to Australia.

PubMed

Shu, J; Hawthorne, L

1996-01-01

"This paper presents an overview of Asian student migration to Australia, together with an analysis of political and educational aspects of the overseas student programme. It focuses on some significant consequences of this flow for Australia. The characteristics of key student groups are contrasted to provide some perspective of the diversity of historical and cultural backgrounds, with the source countries of Malaysia, Indonesia and PRC [China] selected as case studies. Since the issue of PRC students in Australia has attracted considerable public attention and policy consideration, particular focus is placed on their experience." (SUMMARY IN FRE AND SPA) excerpt

Application of optical coherence tomography based microangiography for cerebral imaging

NASA Astrophysics Data System (ADS)

Baran, Utku; Wang, Ruikang K.

2016-03-01

Requirements of in vivo rodent brain imaging are hard to satisfy using traditional technologies such as magnetic resonance imaging and two-photon microscopy. Optical coherence tomography (OCT) is an emerging tool that can easily reach at high speeds and provide high resolution volumetric images with a relatively large field of view for rodent brain imaging. Here, we provide the overview of recent developments of functional OCT based imaging techniques for neuroscience applications on rodents. Moreover, a summary of OCT-based microangiography (OMAG) studies for stroke and traumatic brain injury cases on rodents are provided.

New and Innovative Library Services: Moving with Web 2.0 / Library 2.0 Technology, a Case Study

NASA Astrophysics Data System (ADS)

Sahu, H. K.; Pathak, S. K.; Singh, S. N.

2010-10-01

We give an overview and definition of Web 2.0 and Library 2.0 technology, especially addressing how it changes access to collections for users. We also describe its unlimited possibilities. The various components of Library 2.0 viz blogs, wikis, RSS, instant messaging, social networking, podcasting, and tagging are briefly summarized. Initiatives at three special information centers and libraries (IUCAA — Astronomy and Astrophysics; IIT — Science and Technology; and NIV — Viral Diseases) are described. We conclude with a futuristic view of Library 2.0.

Bunyavirus-Vector Interactions

PubMed Central

Horne, Kate McElroy; Vanlandingham, Dana L.

2014-01-01

The Bunyaviridae family is comprised of more than 350 viruses, of which many within the Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus genera are significant human or agricultural pathogens. The viruses within the Orthobunyavirus, Nairovirus, and Phlebovirus genera are transmitted by hematophagous arthropods, such as mosquitoes, midges, flies, and ticks, and their associated arthropods not only serve as vectors but also as virus reservoirs in many cases. This review presents an overview of several important emerging or re-emerging bunyaviruses and describes what is known about bunyavirus-vector interactions based on epidemiological, ultrastructural, and genetic studies of members of this virus family. PMID:25402172

Disruptive Innovation in Air Measurement Technology: Reality ...

EPA Pesticide Factsheets

This presentation is a big picture overview on the changing state of air measurement technology in the world, with a focus on the introduction of low-cost sensors into the market place. The presentation discusses how these new technologies may be a case study in disruptive innovation for the air pollution measurement field. The intended audience is primarily those with experience in air pollution measurement methods, but much of the talk is accessible to the general public. This is a keynote presentation on emerging air monitoring technology, to be provided at the AWMA measurements conference in March, 2016.

Development and release of phenological data products—A case study in compliance with federal open data policy

USGS Publications Warehouse

Rosemartin, Alyssa H.; Langseth, Madison L.; Crimmins, Theresa M.; Weltzin, Jake F.

2018-01-31

In Autumn 2015, USA National Phenology Network (USA-NPN) staff implemented new U.S. Geological Survey (USGS) data-management policies intended to ensure that the results of Federally funded research are made available to the public. The effort aimed both to improve USA-NPN data releases and to provide a model for similar programs within the USGS. This report provides an overview of the steps taken to ensure compliance, following the USGS Science Data Lifecycle, and provides lessons learned about the data-release process for USGS program leaders and data managers.

The merit of medicinal mushrooms from a pharmaceutical point of view.

PubMed

Lindequist, Ulrike

2013-01-01

Whereas pharmaceuticals prepared by extraction of medicinal plants constitute an important part of evidence-based medicine also in the Western Hemisphere, medicinal mushrooms are mainly used as dietary supplements without declaration of a medical indication. Scientific investigations and case studies from Asian medicine show that fungi have very promising pharmacological potential. This article provides an overview of the principles of authorization and market access of herbal drugs in Europe, with special reference to Germany. The current status regarding mushrooms is reported, with an aim toward supporting the development of legalized pharmaceutical preparations of medicinal mushrooms in Europe.

Clean Restructuring: Design Elements for Low Carbon Wholesale Markets and Beyond

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

Countries around the world are in various stages of power system reform and restructuring to more effectively meet development goals and decarbonization commitments. Changes in social dynamics, technology, business models, and environmental goals are increasing pressure for countries to consider improvements to their power systems. This brochure overviews the 21st Century Power Partnerships thought leadership report that explores the clean restructuring pathway in depth, envisions an end state, and articulates three main areas of consideration for decision makers embarking on a clean restructuring process. The report also details case studies from Germany, Denmark, and Mexico.

Fox transcription factors: from development to disease.

PubMed

Golson, Maria L; Kaestner, Klaus H

2016-12-15

Forkhead box (Fox) transcription factors are evolutionarily conserved in organisms ranging from yeast to humans. They regulate diverse biological processes both during development and throughout adult life. Mutations in many Fox genes are associated with human disease and, as such, various animal models have been generated to study the function of these transcription factors in mechanistic detail. In many cases, the absence of even a single Fox transcription factor is lethal. In this Primer, we provide an overview of the Fox family, highlighting several key Fox transcription factor families that are important for mammalian development. © 2016. Published by The Company of Biologists Ltd.

An Expert System for the Development of Efficient Parallel Code

NASA Technical Reports Server (NTRS)

Jost, Gabriele; Chun, Robert; Jin, Hao-Qiang; Labarta, Jesus; Gimenez, Judit

2004-01-01

We have built the prototype of an expert system to assist the user in the development of efficient parallel code. The system was integrated into the parallel programming environment that is currently being developed at NASA Ames. The expert system interfaces to tools for automatic parallelization and performance analysis. It uses static program structure information and performance data in order to automatically determine causes of poor performance and to make suggestions for improvements. In this paper we give an overview of our programming environment, describe the prototype implementation of our expert system, and demonstrate its usefulness with several case studies.

Apiose: one of nature's witty games.

PubMed

Pičmanová, Martina; Møller, Birger Lindberg

2016-05-01

Apiose is a unique branched-chain pentose found principally in plants. It is a key component of structurally complex cell wall polysaccharides, as well as being present in a large number of naturally occurring secondary metabolites. This review provides a comprehensive overview of the current state of knowledge on the metabolism and natural occurrence of apiose, using cyanogenic glycosides and their related compounds as a case study. The biological function of apiose and of apiosylated compounds is discussed. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Movies and juvenile delinquency: an overview.

PubMed

Snyder, S

1991-01-01

Film viewing may affect the juvenile delinquent through the processes known as social learning and instigation. Identification with the movie and its characters by the delinquent viewer is common, and studies have consistently demonstrated that films can affect delinquents, although in some cases the effects are small. Numerous examples of how films may serve as either the initiator or the final common pathway of delinquent acts are presented. However, prosocial aspects of films dealing with delinquency may exert a positive influence on the juvenile delinquent. Treatment implications of these observations are discussed from social learning and other perspectives.

Directed module detection in a large-scale expression compendium.

PubMed

Fu, Qiang; Lemmens, Karen; Sanchez-Rodriguez, Aminael; Thijs, Inge M; Meysman, Pieter; Sun, Hong; Fierro, Ana Carolina; Engelen, Kristof; Marchal, Kathleen

2012-01-01

Public online microarray databases contain tremendous amounts of expression data. Mining these data sources can provide a wealth of information on the underlying transcriptional networks. In this chapter, we illustrate how the web services COLOMBOS and DISTILLER can be used to identify condition-dependent coexpression modules by exploring compendia of public expression data. COLOMBOS is designed for user-specified query-driven analysis, whereas DISTILLER generates a global regulatory network overview. The user is guided through both web services by means of a case study in which condition-dependent coexpression modules comprising a gene of interest (i.e., "directed") are identified.

Natural antisense RNAs as mRNA regulatory elements in bacteria: a review on function and applications.

PubMed

Saberi, Fatemeh; Kamali, Mehdi; Najafi, Ali; Yazdanparast, Alavieh; Moghaddam, Mehrdad Moosazadeh

2016-01-01

Naturally occurring antisense RNAs are small, diffusible, untranslated transcripts that pair to target RNAs at specific regions of complementarity to control their biological function by regulating gene expression at the post-transcriptional level. This review focuses on known cases of antisense RNA control in prokaryotes and provides an overview of some natural RNA-based mechanisms that bacteria use to modulate gene expression, such as mRNA sensors, riboswitches and antisense RNAs. We also highlight recent advances in RNA-based technology. The review shows that studies on both natural and synthetic systems are reciprocally beneficial.

Growth and Endocrine Function in Tunisian Thalassemia Major Patients.

PubMed

Dhouib, Naouel Guirat; Ben Khaled, Monia; Ouederni, Monia; Besbes, Habib; Kouki, Ridha; Mellouli, Fethi; Bejaoui, Mohamed

2018-01-01

β-thalassemia major (β-TM) is among the most common hereditary disorders imposing high expenses on health-care system worldwide. The patient's survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity in various organs including endocrine glands. This article provides an overview of endocrine disorders in beta-TM patients. This single center investigation enrolled 28 β-TM patients (16 males, 12 females) regularly transfused with packed red cell since early years of life. For each patient were determined: age, sex, number of transfusions received, history of splenectomy and anthropometric parameters. All patients underwent an evaluation of hormonal status including growth, gonadal, thyroid, adrenal cortex, and parathyroid glands. Dual-energy X-ray absorptiometry was used to diagnose low bone mass. Assessment of iron overload status was performed by measuring the serum ferritin concentration and the results of magnetic resonance imaging T 2 *. Growth retardation was found in 16 of the 28 studied patients (57 %). Thirteen among them had delayed puberty. Spontaneous puberty was achieved in 16 cases. Growth hormone (GH) deficiency was found in 10 cases (35 %). Seventeen among the studied patients (60 %) developed disorders of glucose homeostasis. Subclinical hypothyroidism was found in six patients (21 %). Intensive chelation therapy had allowed the reversibility of this complication in five cases. Adrenal Insufficiency was observed in 9 cases (32%). Hypoparathyroidism has occurred in one case. Ten of the 28 studied patients had low bone mass (35%). Twenty-three of the 28 studied patients (82%) had at least one endocrine complication.

Design and life-cycle considerations for unconventional-reservoir wells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miskimins, J.L.

2009-05-15

This paper provides an overview of design and life-cycle considerations for certain unconventional-reservoir wells. An overview of unconventional-reservoir definitions is provided. Well design and life-cycle considerations are addressed from three aspects: upfront reservoir development, initial well completion, and well-life and long-term considerations. Upfront-reservoir-development issues discussed include well spacing, well orientation, reservoir stress orientations, and tubular metallurgy. Initial-well-completion issues include maximum treatment pressures and rates, treatment diversion, treatment staging, flowback and cleanup, and dewatering needs. Well-life and long-term discussions include liquid loading, corrosion, refracturing and associated fracture reorientation, and the cost of abandonment. These design considerations are evaluated with case studiesmore » for five unconventional-reservoir types: shale gas (Barnett shale), tight gas (Jonah feld), tight oil (Bakken play), coalbed methane (CBM) (San Juan basin), and tight heavy oil (Lost Hills field). In evaluating the life cycle and design of unconventional-reservoir wells, 'one size' does not fit all and valuable knowledge and a shortening of the learning curve can be achieved for new developments by studying similar, more-mature fields.« less

Oral dyskinesia: a clinical overview.

PubMed

Blanchet, Pierre J; Rompré, Pierre H; Lavigne, Gilles J; Lamarche, Claude

2005-01-01

Dentists may be the first health care professionals to recognize unusual and abnormal oral movements collectively termed oral dyskinesias. The aims of this clinical overview are to raise the dental community's awareness about this important and complex topic and describe the clinical features and management of the main entities. A MEDLINE search of the different entities reported in the English and French literature was conducted. The main findings of a field study on oral dyskinesia were also reviewed. Involuntary movement disorders are often drug related. In other cases, excessive oral movements may occur at any age in relation to various neuropsychiatric conditions. Orofacial dystonia apparently triggered by dental procedures has also been reported. Edentulousness has been associated with oral stereotypes. In a survey of 352 edentulous elderly individuals attending daycare centers, only 7% displayed visible oral sterotypes, and ill-fitting dentures were suggested as a possible triggering factor for the majority. A multidisciplinary evaluation is desirable in the care of individuals with oral dyskinesia and in the selection of those who may benefit from a prosthodontic approach. A good knowledge of potentially offending drugs may allow avoidance of unnecessary procedures.

An Overview on Wireless Sensor Networks Technology and Evolution

PubMed Central

Buratti, Chiara; Conti, Andrea; Dardari, Davide; Verdone, Roberto

2009-01-01

Wireless sensor networks (WSNs) enable new applications and require non-conventional paradigms for protocol design due to several constraints. Owing to the requirement for low device complexity together with low energy consumption (i.e., long network lifetime), a proper balance between communication and signal/data processing capabilities must be found. This motivates a huge effort in research activities, standardization process, and industrial investments on this field since the last decade. This survey paper aims at reporting an overview of WSNs technologies, main applications and standards, features in WSNs design, and evolutions. In particular, some peculiar applications, such as those based on environmental monitoring, are discussed and design strategies highlighted; a case study based on a real implementation is also reported. Trends and possible evolutions are traced. Emphasis is given to the IEEE 802.15.4 technology, which enables many applications of WSNs. Some example of performance characteristics of 802.15.4-based networks are shown and discussed as a function of the size of the WSN and the data type to be exchanged among nodes. PMID:22423202

Spondylodiskitis secondary to Streptococcus equi subspecies zooepidemicus.

PubMed

Bhatia, Ravi; Bhanot, Nitin

2012-01-01

Streptococcus equi subspecies zooepidemicus, traditionally classified under Group C Streptococci, is primarily a veterinary pathogen. Rarely, it may cause infections such as bacteremia, meningitis, endocarditis and pneumonia in humans. Musculoskeletal infections secondary to this pathogen are very uncommon. The authors present the first case of osteomyelitis due to S. zooepidemicus in a farmer who had close contact with a dead horse. The authors review all cases of osteoarticular infections secondary to this microbe, in addition to providing an overview of clinical manifestations, treatment and outcome of this infection.

State of the Art for Design and Construction of Sand Compaction Piles

DTIC Science & Technology

1987-11-01

Walz, Headquarters, US Army Corps of Engineers (HQUSACE), was REMR Technical Monitor. The REMR Overview Committee, consisted of Mr. John R. Nikel ... Wire Vibrator Hopper Casing Pipe Air Line Power Line Sand Skip Bucket Front End Loader Figure 2. Typical equipment used to construct a sand...8217~~~~--­ Rubber Packing Wire Inlet for air to close valve and press sand down ..,...__ Air lnl~ot: Figure 5. Special valve used to seal the casing when

Situation awareness acquired from monitoring process plants - the Process Overview concept and measure.

PubMed

Lau, Nathan; Jamieson, Greg A; Skraaning, Gyrd

2016-07-01

We introduce Process Overview, a situation awareness characterisation of the knowledge derived from monitoring process plants. Process Overview is based on observational studies of process control work in the literature. The characterisation is applied to develop a query-based measure called the Process Overview Measure. The goal of the measure is to improve coupling between situation and awareness according to process plant properties and operator cognitive work. A companion article presents the empirical evaluation of the Process Overview Measure in a realistic process control setting. The Process Overview Measure demonstrated sensitivity and validity by revealing significant effects of experimental manipulations that corroborated with other empirical results. The measure also demonstrated adequate inter-rater reliability and practicality for measuring SA based on data collected by process experts. Practitioner Summary: The Process Overview Measure is a query-based measure for assessing operator situation awareness from monitoring process plants in representative settings.

Delivery arrangements for health systems in low-income countries: an overview of systematic reviews

PubMed Central

Ciapponi, Agustín; Lewin, Simon; Herrera, Cristian A; Opiyo, Newton; Pantoja, Tomas; Paulsen, Elizabeth; Rada, Gabriel; Wiysonge, Charles S; Bastías, Gabriel; Dudley, Lilian; Flottorp, Signe; Gagnon, Marie-Pierre; Garcia Marti, Sebastian; Glenton, Claire; Okwundu, Charles I; Peñaloza, Blanca; Suleman, Fatima; Oxman, Andrew D

2017-01-01

Background Delivery arrangements include changes in who receives care and when, who provides care, the working conditions of those who provide care, coordination of care amongst different providers, where care is provided, the use of information and communication technology to deliver care, and quality and safety systems. How services are delivered can have impacts on the effectiveness, efficiency and equity of health systems. This broad overview of the findings of systematic reviews can help policymakers and other stakeholders identify strategies for addressing problems and improve the delivery of services. Objectives To provide an overview of the available evidence from up-to-date systematic reviews about the effects of delivery arrangements for health systems in low-income countries. Secondary objectives include identifying needs and priorities for future evaluations and systematic reviews on delivery arrangements and informing refinements of the framework for delivery arrangements outlined in the review. Methods We searched Health Systems Evidence in November 2010 and PDQ-Evidence up to 17 December 2016 for systematic reviews. We did not apply any date, language or publication status limitations in the searches. We included well-conducted systematic reviews of studies that assessed the effects of delivery arrangements on patient outcomes (health and health behaviours), the quality or utilisation of healthcare services, resource use, healthcare provider outcomes (such as sick leave), or social outcomes (such as poverty or employment) and that were published after April 2005. We excluded reviews with limitations important enough to compromise the reliability of the findings. Two overview authors independently screened reviews, extracted data, and assessed the certainty of evidence using GRADE. We prepared SUPPORT Summaries for eligible reviews, including key messages, 'Summary of findings' tables (using GRADE to assess the certainty of the evidence), and assessments of the relevance of findings to low-income countries. Main results We identified 7272 systematic reviews and included 51 of them in this overview. We judged 6 of the 51 reviews to have important methodological limitations and the other 45 to have only minor limitations. We grouped delivery arrangements into eight categories. Some reviews provided more than one comparison and were in more than one category. Across these categories, the following intervention were effective; that is, they have desirable effects on at least one outcome with moderate- or high-certainty evidence and no moderate- or high-certainty evidence of undesirable effects. Who receives care and when: queuing strategies and antenatal care to groups of mothers. Who provides care: lay health workers for caring for people with hypertension, lay health workers to deliver care for mothers and children or infectious diseases, lay health workers to deliver community-based neonatal care packages, midlevel health professionals for abortion care, social support to pregnant women at risk, midwife-led care for childbearing women, non-specialist providers in mental health and neurology, and physician-nurse substitution. Coordination of care: hospital clinical pathways, case management for people living with HIV and AIDS, interactive communication between primary care doctors and specialists, hospital discharge planning, adding a service to an existing service and integrating delivery models, referral from primary to secondary care, physician-led versus nurse-led triage in emergency departments, and team midwifery. Where care is provided: high-volume institutions, home-based care (with or without multidisciplinary team) for people living with HIV and AIDS, home-based management of malaria, home care for children with acute physical conditions, community-based interventions for childhood diarrhoea and pneumonia, out-of-facility HIV and reproductive health services for youth, and decentralised HIV care. Information and communication technology: mobile phone messaging for patients with long-term illnesses, mobile phone messaging reminders for attendance at healthcare appointments, mobile phone messaging to promote adherence to antiretroviral therapy, women carrying their own case notes in pregnancy, interventions to improve childhood vaccination. Quality and safety systems: decision support with clinical information systems for people living with HIV/AIDS. Complex interventions (cutting across delivery categories and other health system arrangements): emergency obstetric referral interventions. Authors' conclusions A wide range of strategies have been evaluated for improving delivery arrangements in low-income countries, using sound systematic review methods in both Cochrane and non-Cochrane reviews. These reviews have assessed a range of outcomes. Most of the available evidence focuses on who provides care, where care is provided and coordination of care. For all the main categories of delivery arrangements, we identified gaps in primary research related to uncertainty about the applicability of the evidence to low-income countries, low- or very low-certainty evidence or a lack of studies. Effects of delivery arrangements for health systems in low-income countries What is the aim of this overview? The aim of this Cochrane Overview is to provide a broad summary of what is known about the effects of delivery arrangements for health systems in low-income countries. This overview is based on 51 systematic reviews. These systematic reviews searched for studies that evaluated different types of delivery arrangements. The reviews included a total of 850 studies. This overview is one of a series of four Cochrane Overviews that evaluate health system arrangements. What was studied in the overview? Delivery arrangements include changes in who receives care and when, who provides care, the working conditions of those who provide care, coordination of care amongst different health care providers, where care is provided, the use of information and communication technology to deliver care, and quality and safety systems. How services are delivered can have impacts on the effectiveness, efficiency and equity of health systems. This overview can help policymakers and other stakeholders to identify evidence-informed strategies to improve the delivery of services. What are the main results of the overview? When focusing only on evidence assessed as high to moderate certainty, the overview points to a number of delivery arrangements that had at least one desirable outcome and no evidence of any undesirable outcomes. These include the following: Who receives care and when - Queuing strategies - Group antenatal care Who provides care – role expansion or task shifting - Lay or community health workers supporting the care of people with hypertension - Community-based neonatal packages that include additional training of outreach workers - Lay health workers to deliver care for mothers and children or for infectious diseases - Mid-level, non-physician providers for abortion care - Health workers providing social support during at-risk pregnancies - Midwife-led care for childbearing women and their infants - Non-specialist health workers or other professionals with health roles to help people with mental, neurological and substance-abuse disorders - Nurses substituting for physicians in providing care Coordination of care - Structured multidisciplinary care plans (care pathways) used by health care providers in hospitals to detail essential steps in the care of people with a specific clinical problem - Interactive communication between collaborating primary care physicians and specialist physicians in outpatient care - Planning to facilitate patients’ discharge from hospital to home - Adding a new health service to an existing service and integrating services in health care delivery - Integrating vaccination with other healthcare services - Using physicians rather than nurses to lead triage in emergency departments - Groups or teams of midwives providing care for a group of women during pregnancy and childbirth and after childbirth Where care is provided – site of service delivery - Clinics or hospitals that manage a high volume of people living with HIV and AIDS rather than smaller volumes - Intensive home-based care for people living with HIV and AIDS - Home-based management of malaria in children - Providing care closer to home for children with long-term health conditions - Community-based interventions using lay health workers for childhood diarrhoea and pneumonia - Youth HIV and reproductive health services provided outside of health facilities - Decentralising care for initiation and maintenance of HIV and AIDS medicine treatment to peripheral health centres or lower levels of healthcare Information and communication technology - Mobile phone messaging for people with long-term illnesses - Mobile phone messaging reminders for attendance at healthcare appointments - Mobile phone messaging to promote adherence to antiretroviral therapy - Women carrying their own case notes in pregnancy - Information and communication interventions to improve childhood vaccination coverage Quality and safety systems - Establishing clinical information systems to organize patient data for people living with HIV and AIDS Packages that include multiple interventions - Interventions to improve referral for emergency care during pregnancy and childbirth How up to date is this overview? The overview authors searched for systematic reviews that had been published up to 17 December 2016. PMID:28901005

Optimizing Wartime Materiel Delivery: An Overview of DoD containerization. Volume 3. Annotated Bibliography

DOT National Transportation Integrated Search

1988-10-01

This annotated bibliography, Volume III of the study entitled, Optimizing Wartime Materiel Delivery: An overview of DOD Containerization Efforts, documents studies related to containerization. Several objectives of the study were defined. These inclu...

An overview of the genetic dissection of complex traits.

PubMed

Rao, D C

2008-01-01

Thanks to the recent revolutionary genomic advances such as the International HapMap consortium, resolution of the genetic architecture of common complex traits is beginning to look hopeful. While demonstrating the feasibility of genome-wide association (GWA) studies, the pathbreaking Wellcome Trust Case Control Consortium (WTCCC) study also serves to underscore the critical importance of very large sample sizes and draws attention to potential problems, which need to be addressed as part of the study design. Even the large WTCCC study had vastly inadequate power for several of the associations reported (and confirmed) and, therefore, most of the regions harboring relevant associations may not be identified anytime soon. This chapter provides an overview of some of the key developments in the methodological approaches to genetic dissection of common complex traits. Constrained Bayesian networks are suggested as especially useful for analysis of pathway-based SNPs. Likewise, composite likelihood is suggested as a promising method for modeling complex systems. It discusses the key steps in a study design, with an emphasis on GWA studies. Potential limitations highlighted by the WTCCC GWA study are discussed, including problems associated with massive genotype imputation, analysis of pooled national samples, shared controls, and the critical role of interactions. GWA studies clearly need massive sample sizes that are only possible through genuine collaborations. After all, for common complex traits, the question is not whether we can find some pieces of the puzzle, but how large and what kind of a sample we need to (nearly) solve the genetic puzzle.

An overview of age estimation in forensic anthropology: perspectives and practical considerations.

PubMed

Márquez-Grant, Nicholas

2015-01-01

Information on methods of age estimation in physical anthropology, in particular with regard to age-at-death from human skeletal remains, is widely available in the literature. However, the practicalities and real challenges faced in forensic casework are not always highlighted. To provide a practitioner's perspective, regarding age estimation in forensic anthropology (both in the living as well as the dead), with an emphasis on the types of cases, the value of such work and its challenges and limitations. The paper reviews the current literature on age estimation with a focus on forensic anthropology, but it also brings the author's personal perspective derived from a number of forensic cases. Although much is known about what methods to use, but not always how to apply them, little attention has been given in the literature to the real practicalities faced by forensic anthropologists, for example: the challenges in different types of scenarios; how to report age estimations; responsibilities; and ethical concerns. This paper gathers some of these aspects into one overview which includes the value of such work and the practical challenges, not necessarily with the methods themselves, but also with regard to how these are applied in the different cases where age estimation is required.

[Corrected transposition of the great arteries].

PubMed

Alva-Espinosa, Carlos

2016-01-01

Corrected transposition of the great arteries is one of the most fascinating entities in congenital heart disease. The apparent corrected condition is only temporal. Over time, most patients develop systemic heart failure, even in the absence of associated lesions. With current imaging studies, precise visualization is achieved in each case though the treatment strategy remains unresolved. In asymptomatic patients or cases without associated lesions, focalized follow-up to assess systemic ventricular function and the degree of tricuspid valve regurgitation is important. In cases with normal ventricular function and mild tricuspid failure, it seems unreasonable to intervene surgically. In patients with significant associated lesions, surgery is indicated. In the long term, the traditional approach may not help tricuspid regurgitation and systemic ventricular failure. Anatomical correction is the proposed alternative to ease the right ventricle overload and to restore the systemic left ventricular function. However, this is a prolonged operation and not without risks and long-term complications. In this review the clinical, diagnostic, and therapeutic aspects are overviewed in the light of the most significant and recent literature.

A case report of neonatal thyrotoxicosis due to maternal autoimmune hyperthyroidism.

PubMed

Markham, Lori A; Stevens, Debra L

2003-12-01

A case of neonatal thyrotoxicosis secondary to maternal autoimmune hyperthyroidism is reported in an infant born at 34 weeks gestation who presented with tachycardia, jitteriness, diarrhea, and a small goiter. Propranolol and oxygen were used to treat high-output cardiac failure and transient persistent pulmonary hypertension. The infant's response to propylthiouracil therapy, gradual resolution of cardiac and systemic symptoms, and normaliziation of thyroid studies are described. Thyroid physiology and function and the special considerations in a premature infant are reviewed. An overview of maternal autoimmune hyperthyroidism and the implications for the developing fetus and neonate are presented. The risk factors for, and clinical presentation of, hyperthyroidism are outlined and treatment strategies highlighted. The nursing care of infants with hyperthyroidism is carefully described with an emphasis on the surveillance for and management of multisystem manifestations.

The LatHyS database for planetary plasma environment investigations: Overview and a case study of data/model comparisons

NASA Astrophysics Data System (ADS)

Modolo, R.; Hess, S.; Génot, V.; Leclercq, L.; Leblanc, F.; Chaufray, J.-Y.; Weill, P.; Gangloff, M.; Fedorov, A.; Budnik, E.; Bouchemit, M.; Steckiewicz, M.; André, N.; Beigbeder, L.; Popescu, D.; Toniutti, J.-P.; Al-Ubaidi, T.; Khodachenko, M.; Brain, D.; Curry, S.; Jakosky, B.; Holmström, M.

2018-01-01

We present the Latmos Hybrid Simulation (LatHyS) database, which is dedicated to the investigations of planetary plasma environment. Simulation results of several planetary objects (Mars, Mercury, Ganymede) are available in an online catalogue. The full description of the simulations and their results is compliant with a data model developped in the framework of the FP7 IMPEx project. The catalogue is interfaced with VO-visualization tools such AMDA, 3DView, TOPCAT, CLweb or the IMPEx portal. Web services ensure the possibilities of accessing and extracting simulated quantities/data. We illustrate the interoperability between the simulation database and VO-tools using a detailed science case that focuses on a three-dimensional representation of the solar wind interaction with the Martian upper atmosphere, combining MAVEN and Mars Express observations and simulation results.

Mapping R&D within Multinational Networks: Evidence from the Electronics Industry

NASA Astrophysics Data System (ADS)

Urze, Paula; Manatos, Maria João

Based on the final results of the R&D.COM - Local R&D COMpetencies within Global Value Chains project, this paper aims at mapping the trajectories of delocalised R&D units within a multinational’s global strategy and designing the knowledge flows within the global value chain. This analysis was performed using typologies proposed in the theoretical framework, which help us to have an overview of the network. The methodology is grounded on one extended case study that involves a local R&D unit (Portugal), a foreign R&D unit (Netherlands) and the headquarters (Norway) - developed on a multinational from the electronics industry. This case is an example of a multinational company where R&D is developed mainly in the headquarters but it is also delocalised to some subsidiaries with a certain level of autonomy.