Sample records for cavitation oxidation process

  1. Study of ultrasonic cavitation during extraction of the peanut oil at varying frequencies.

    PubMed

    Zhang, Lei; Zhou, Cunshan; Wang, Bei; Yagoub, Abu El-Gasim A; Ma, Haile; Zhang, Xiao; Wu, Mian

    2017-07-01

    The ultrasonic extraction of oils is a typical physical processing technology. The extraction process was monitored from the standpoint of the oil quality and efficiency of oil extraction. In this study, the ultrasonic cavitation fields were measured by polyvinylidene fluoride (PVDF) sensor. Waveform of ultrasonic cavitation fields was gained and analyzed. The extraction yield and oxidation properties were compared. The relationship between the fields and cavitation oxidation was established. Numerical calculation of oscillation cycle was done for the cavitation bubbles. Results showed that the resonance frequency, f r , of the oil extraction was 40kHz. At f r , the voltage amplitude was the highest; the time was the shortest as reaching the amplitude of the waveform. Accordingly, the cavitation effect worked most rapidly, resulting in the strongest cavitation intensity. The extraction yield and oxidation properties were closely related to the cavitation effect. It controlled the cavitation oxidation effectively from the viewpoint of chemical and physical aspects. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Effective method of treatment of effluents from production of bitumens under basic pH conditions using hydrodynamic cavitation aided by external oxidants.

    PubMed

    Boczkaj, Grzegorz; Gągol, Michał; Klein, Marek; Przyjazny, Andrzej

    2018-01-01

    Utilization of cavitation in advanced oxidation processes (AOPs) is a promising trend in research on treatment of industrial effluents. The paper presents the results of investigations on the use of hydrodynamic cavitation aided by additional oxidation processes (O 3 /H 2 O 2 /Peroxone) to reduce the total pollution load in the effluent from the production of bitumens. A detailed analysis of changes in content of volatile organic compounds (VOCs) for all processes studied was also performed. The studies revealed that the most effective treatment process involves hydrodynamic cavitation aided by ozonation (40% COD reduction and 50% BOD reduction). The other processes investigated (hydrodynamic cavitation+H 2 O 2 , hydrodynamic cavitation+Peroxone and hydrodynamic cavitation alone) ensure reduction of COD by 20, 25 and 13% and reduction of BOD by 49, 32 and 18%, respectively. The results of this research revealed that most of the VOCs studied are effectively degraded. The formation of byproducts is one of the aspects that must be considered in evaluation of the AOPs studied. This work confirmed that furfural is one of the byproducts whose concentration increased during treatment by hydrodynamic cavitation alone as well as hydrodynamic cavitation aided by H 2 O 2 as an external oxidant and it should be controlled during treatment processes. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Highly effective degradation of selected groups of organic compounds by cavitation based AOPs under basic pH conditions.

    PubMed

    Gągol, Michał; Przyjazny, Andrzej; Boczkaj, Grzegorz

    2018-07-01

    Cavitation has become on the most often applied methods in a number of industrial technologies. In the case of oxidation of organic pollutants occurring in the aqueous medium, cavitation forms the basis of numerous advanced oxidation processes (AOPs). This paper presents the results of investigations on the efficiency of oxidation of the following groups of organic compounds: organosulfur, nitro derivatives of benzene, BTEX, and phenol and its derivatives in a basic model effluent using hydrodynamic and acoustic cavitation combined with external oxidants, i.e., hydrogen peroxide, ozone and peroxone. The studies revealed that the combination of cavitation with additional oxidants allows 100% oxidation of the investigated model compounds. However, individual treatments differed with respect to the rate of degradation. Hydrodynamic cavitation aided by peroxone was found to be the most effective treatment (100% oxidation of all the investigated compounds in 60 min). When using hydrodynamic and acoustic cavitation alone, the effectiveness of oxidation was diversified. Under these conditions, nitro derivatives of benzene and phenol and its derivatives were found to be resistant to oxidation. In addition, hydrodynamic cavitation was found to be more effective in degradation of model compounds than acoustic cavitation. The results of investigations presented in this paper compare favorably with the investigations on degradation of organic contaminants using AOPs under conditions of basic pH published thus far. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Treatment of wastewater streams containing phenolic compounds using hybrid techniques based on cavitation: a review of the current status and the way forward.

    PubMed

    Gogate, Parag R

    2008-01-01

    Phenolic compounds, including its chloro and nitro derivatives, contribute significantly to environmental hazards due to high degree of toxicity as well as improper disposal methods. Cavitation can be used for degradation of phenolic compounds and recently Kidak and Ince [R. Kidak, N.H. Ince, Ultrason. Sonochem. 13 (2006) 195] have given an interesting review on the application of cavitation for destruction of phenolic compounds. A main finding of their work and generally accepted fact is that cavitation alone cannot be an economical technique for wastewater treatment. The present work overviews the different ways in which the cavitation phenomena can be intensified by using additives and/or combining cavitation with other oxidation processes. Hybrid methods viz. Ultrasound/H2O2 or ozone, cavitation assisted by use of catalysts/additives, sonophotocatalytic oxidation and cavitation coupled with biological oxidation have been discussed with specific reference to the principle behind the expected synergism, different reactor configurations used and optimum considerations for the operating and geometric parameters. Some of the important works evaluating the application of these processes for the destruction of phenolic compounds has been described in details. Some guidelines for the future work required to facilitate efficient large-scale operation have also been given.

  5. Degradation of 2,4-dinitrophenol using a combination of hydrodynamic cavitation, chemical and advanced oxidation processes.

    PubMed

    Bagal, Manisha V; Gogate, Parag R

    2013-09-01

    In the present work, degradation of 2,4-dinitrophenol (DNP), a persistent organic contaminant with high toxicity and very low biodegradability has been investigated using combination of hydrodynamic cavitation (HC) and chemical/advanced oxidation. The cavitating conditions have been generated using orifice plate as a cavitating device. Initially, the optimization of basic operating parameters have been done by performing experiments over varying inlet pressure (over the range of 3-6 bar), temperature (30 °C, 35 °C and 40 °C) and solution pH (over the range of 3-11). Subsequently, combined treatment strategies have been investigated for process intensification of the degradation process. The effect of HC combined with chemical oxidation processes such as hydrogen peroxide (HC/H2O2), ferrous activated persulfate (HC/Na2S2O8/FeSO4) and HC coupled with advanced oxidation processes such as conventional Fenton (HC/FeSO4/H2O2), advanced Fenton (HC/Fe/H2O2) and Fenton-like process (HC/CuO/H2O2) on the extent of degradation of DNP have also been investigated at optimized conditions of pH 4, temperature of 35 °C and inlet pressure of 4 bar. Kinetic study revealed that degradation of DNP fitted first order kinetics for all the approaches under investigation. Complete degradation with maximum rate of DNP degradation has been observed for the combined HC/Fenton process. The energy consumption analysis for hydrodynamic cavitation based process has been done on the basis of cavitational yield. Degradation intermediates have also been identified and quantified in the current work. The synergistic index calculated for all the combined processes indicates HC/Fenton process is more feasible than the combination of HC with other Fenton like processes. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Effect of hydrodynamic cavitation on the rate of OH-radical formation in the presence of hydrogen peroxide

    NASA Astrophysics Data System (ADS)

    Aseev, D. G.; Batoeva, A. A.

    2014-01-01

    It is shown experimentally that hydrogen peroxide is the source of OH-radicals at low-pressure hydrodynamic cavitation. Major preconditions for the intensification of oxidative destruction processes in organic pollutants with an added cavitation stimulus are determined.

  7. Combined treatment technology based on synergism between hydrodynamic cavitation and advanced oxidation processes.

    PubMed

    Gogate, Parag R; Patil, Pankaj N

    2015-07-01

    The present work highlights the novel approach of combination of hydrodynamic cavitation and advanced oxidation processes for wastewater treatment. The initial part of the work concentrates on the critical analysis of the literature related to the combined approaches based on hydrodynamic cavitation followed by a case study of triazophos degradation using different approaches. The analysis of different combinations based on hydrodynamic cavitation with the Fenton chemistry, advanced Fenton chemistry, ozonation, photocatalytic oxidation, and use of hydrogen peroxide has been highlighted with recommendations for important design parameters. Subsequently degradation of triazophos pesticide in aqueous solution (20 ppm solution of commercially available triazophos pesticide) has been investigated using hydrodynamic cavitation and ozonation operated individually and in combination for the first time. Effect of different operating parameters like inlet pressure (1-8 bar) and initial pH (2.5-8) have been investigated initially. The effect of addition of Fenton's reagent at different loadings on the extent of degradation has also been investigated. The combined method of hydrodynamic cavitation and ozone has been studied using two approaches of injecting ozone in the solution tank and at the orifice (at the flow rate of 0.576 g/h and 1.95 g/h). About 50% degradation of triazophos was achieved by hydrodynamic cavitation alone under optimized operating parameters. About 80% degradation of triazophos was achieved by combination of hydrodynamic cavitation and Fenton's reagent whereas complete degradation was achieved using combination of hydrodynamic cavitation and ozonation. TOC removal of 96% was also obtained for the combination of ozone and hydrodynamic cavitation making it the best treatment strategy for removal of triazophos. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. CAV-OX CAVITATION OXIDIATION PROCESS - MAGNUM WATER TECHNOLOGY, INC. - APPLICATIONS ANALYSIS REPORT

    EPA Science Inventory

    This report evaluates the ability of the CAV-OX cavitation oxidation process to remove volatile organic compounds (VOC) present in aqueous wastes. This report also presents economic data based on the Superfund Innovative Technology Evaluation (SITE) Program demonstration and nine...

  9. Application of salicylic acid dosimetry to evaluate hydrodynamic cavitation as an advanced oxidation process.

    PubMed

    Arrojo, S; Nerín, C; Benito, Y

    2007-03-01

    The generation of OH* radicals inside hydrodynamic cavitation bubbles was monitored using a salicylic acid dosimeter. The reaction of this scavenger with OH* produces 2,5-dihydroxybenzoic acid (2,5-DHB) and, to a lesser degree, 2,3-DHB. The former, is a specific reaction product that can be determined with a very high sensitivity using HPLC-IF. This method has been applied to study the influence of the flow-rate and the solution pH for a given cavitation chamber geometry. The salicylic dosimetry has proven especially suitable for the characteristic time scales of hydrodynamic cavitation (higher than those of ultrasonic cavitation), which usually gives rise to recombination of radicals before they can reach the liquid-phase. Working at low pH the hydrophobic salicylic acid migrates to the gas-liquid interface and reacts with the OH* radicals, increasing the trapping efficiency of the dosimeter. Hydrodynamic cavitation works as a very low frequency sonochemical reactor, and therefore its potential as an Advanced Oxidation Process might be limited to reactions at the gas-liquid interface and inner bubble (i.e. with volatiles and/or hydrophobic substances).

  10. Hybrid reactor based on combined cavitation and ozonation: from concept to practical reality.

    PubMed

    Gogate, P R; Mededovic-Thagard, S; McGuire, D; Chapas, G; Blackmon, J; Cathey, R

    2014-03-01

    The present work gives an in depth discussion related to the development of a hybrid advanced oxidation reactor, which can be effectively used for the treatment of various types of water. The reactor is based on the principle of intensifying degradation/disinfection using a combination of hydrodynamic cavitation, acoustic cavitation, ozone injection and electrochemical oxidation/precipitation. Theoretical studies have been presented to highlight the uniform distribution of the cavitational activity and enhanced generation of hydroxyl radicals in the cavitation zone, as well as higher turbulence in the main reactor zone. The combination of these different oxidation technologies have been shown to result in enhanced water treatment ability, which can be attributed to the enhanced generation of hydroxyl radicals, enhanced contact of ozone and contaminants, and the elimination of mass transfer resistances during electrochemical oxidation/precipitation. Compared to the use of individual approaches, the hybrid reactor is expected to intensify the treatment process by 5-20 times, depending on the application in question, which can be confirmed based on the literature illustrations. Also, the use of Ozonix® has been successfully proven while processing recycled fluids at commercial sites on over 750 oil and natural gas wells during hydraulic operations around the United States. The superiority of the hybrid process over conventional chemical treatments in terms of bacteria and scale reduction as well as increased water flowability and better chemical compatibility, which is a key requirement for oil and gas applications, has been established. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. Evaluation of inertial cavitation activity in tissue through measurement of oxidative stress.

    PubMed

    Prieur, Fabrice; Pialoux, Vincent; Mestas, Jean-Louis; Mury, Pauline; Skinner, Sarah; Lafon, Cyril

    2015-09-01

    Ultrasound cavitation is an essential mechanism involved in the therapeutic local enhancement of drug delivery by ultrasound for cancer treatment. Inertial cavitation also triggers chemical reactions that generate free radicals and subsequent oxidative stress in the tissue. The aim of this study was to measure the oxidative stress induced by inertial cavitation in ex vivo tissue and to test the association between the exposure conditions and the oxidative stress. A confocal ultrasound setup was used to sonicate and create inertial cavitation in freshly excised adipose pig tissue. The ex vivo tissue samples were then processed to measure the quantity of malondialdehyde (MDA), an end-product of polyunsaturated free fatty acid oxidation. The creation of hydroxyterephthalic acid (HTA) from the reaction of terephthalic acid (TA) with free radicals in water was also quantified in vitro. Samples were sonicated for different durations using various amplitudes for the applied pressure. The results showed a minimum 2-fold increase in the amount of detected MDA in the sonicated tissue samples compared to baseline clearly suggesting the generation of free radicals by inertial cavitation. The method exhibited a moderate dependence of MDA generated upon the duration of exposure (R(2)=057,p<0.0001). The average increase in MDA concentration was approximately 2-fold, 5-fold, 6-fold, and 9-fold for exposure durations per unit of volume of 0.13, 0.17, 0.25, and 0.50s/mm(3), respectively. The results showed no statistically significant dependence on the amplitude of the pressure within the used range. Both pressure amplitude and exposure duration, however, influenced the HTA concentration (R(2)>0.95,p<0.0001). This biochemical method can be used on ex vivo tissue to detect the generation of free radicals induced by inertial cavitation. In large enough sample populations, the cavitation activity is linked to the exposure conditions of the sonication. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Determination of sulfuric acid concentration for anti-cavitation characteristics of Al alloy by two step anodizing process to forming nano porous.

    PubMed

    Lee, Seung-Jun; Kim, Seong-Kweon; Jeong, Jae-Yong; Kim, Seong-Jong

    2014-12-01

    Al alloy is a highly active metal but forms a protective oxide film having high corrosion resistance in atmosphere environment. However, the oxide film is not suitable for practical use, since the thickness of the film is not uniform and it is severly altered with formation conditions. This study focused on developing an aluminum anodizing layer having hardness, corrosion resistance and abrasion resistance equivalent to a commercial grade protective layer. Aluminum anodizing layer was produced by two-step aluminum anodizing oxide (AAO) process with different sulfuric acid concentrations, and the cavitation characteristics of the anodized coating layer was investigated. In hardness measurement, the anodized coating layer produced with 15 vol.% of sulfuric acid condition had the highest value of hardness but exhibited poor cavitation resistance due to being more brittle than those with other conditions. The 10 vol.% of sulfuric acid condition was thus considered to be the optimum condition as it had the lowest weight loss and damage depth.

  13. Current knowledge and potential applications of cavitation technologies for the petroleum industry.

    PubMed

    Avvaru, Balasubrahmanyam; Venkateswaran, Natarajan; Uppara, Parasuveera; Iyengar, Suresh B; Katti, Sanjeev S

    2018-04-01

    Technologies based on cavitation, produced by either ultrasound or hydrodynamic means, are part of growing literature for individual refinery unit processes. In this review, we have explained the mechanism through which these cavitation technologies intensify individual unit processes such as enhanced oil recovery, demulsification of water in oil emulsions during desalting stage, crude oil viscosity reduction, oxidative desulphurisation/demetallization, and crude oil upgrading. Apart from these refinery processes, applications of this technology are also mentioned for other potential crude oil sources such as oil shale and oil sand extraction. The relative advantages and current situation of each application/process at commercial scale is explained. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. DEMONSTRATION BULLETIN: CAV-OX ULTRAVIOLET OXIDATION PROCESS MAGNUM WATER TECHNOLOGY

    EPA Science Inventory

    The CAV-OX® technology (see Fig- ure 1) destroys organic contaminants, including chlorinated hy- drocarbons, in water. The process uses hydrogen peroxide, hy- drodynamic cavitation, and ultraviolet (UV) radiation to photolyze and oxidize organic compounds present in water at ...

  15. Cavitation and non-cavitation regime for large-scale ultrasonic standing wave particle separation systems--In situ gentle cavitation threshold determination and free radical related oxidation.

    PubMed

    Johansson, Linda; Singh, Tanoj; Leong, Thomas; Mawson, Raymond; McArthur, Sally; Manasseh, Richard; Juliano, Pablo

    2016-01-01

    We here suggest a novel and straightforward approach for liter-scale ultrasound particle manipulation standing wave systems to guide system design in terms of frequency and acoustic power for operating in either cavitation or non-cavitation regimes for ultrasound standing wave systems, using the sonochemiluminescent chemical luminol. We show that this method offers a simple way of in situ determination of the cavitation threshold for selected separation vessel geometry. Since the pressure field is system specific the cavitation threshold is system specific (for the threshold parameter range). In this study we discuss cavitation effects and also measure one implication of cavitation for the application of milk fat separation, the degree of milk fat lipid oxidation by headspace volatile measurements. For the evaluated vessel, 2 MHz as opposed to 1 MHz operation enabled operation in non-cavitation or low cavitation conditions as measured by the luminol intensity threshold method. In all cases the lipid oxidation derived volatiles were below the human sensory detection level. Ultrasound treatment did not significantly influence the oxidative changes in milk for either 1 MHz (dose of 46 kJ/L and 464 kJ/L) or 2 MHz (dose of 37 kJ/L and 373 kJ/L) operation. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Wastewater treatment using hybrid treatment schemes based on cavitation and Fenton chemistry: a review.

    PubMed

    Bagal, Manisha V; Gogate, Parag R

    2014-01-01

    Advanced oxidation processes such as cavitation and Fenton chemistry have shown considerable promise for wastewater treatment applications due to the ease of operation and simple reactor design. In this review, hybrid methods based on cavitation coupled with Fenton process for the treatment of wastewater have been discussed. The basics of individual processes (Acoustic cavitation, Hydrodynamic cavitation, Fenton chemistry) have been discussed initially highlighting the need for combined processes. The different types of reactors used for the combined processes have been discussed with some recommendations for large scale operation. The effects of important operating parameters such as solution temperature, initial pH, initial pollutant concentration and Fenton's reagent dosage have been discussed with guidelines for selection of optimum parameters. The optimization of power density is necessary for ultrasonic processes (US) and combined processes (US/Fenton) whereas the inlet pressure needs to be optimized in the case of Hydrodynamic cavitation (HC) based processes. An overview of different pollutants degraded under optimized conditions using HC/Fenton and US/Fenton process with comparison with individual processes have been presented. It has been observed that the main mechanism for the synergy of the combined process depends on the generation of additional hydroxyl radicals and its proper utilization for the degradation of the pollutant, which is strongly dependent on the loading of hydrogen peroxide. Overall, efficient wastewater treatment with high degree of energy efficiency can be achieved using combined process operating under optimized conditions, as compared to the individual process. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Cavitational synthesis of nanostructured inorganic materials for enhanced heterogeneous catalysis

    NASA Astrophysics Data System (ADS)

    Krausz, Ivo Michael

    The synthesis of nanostructured inorganic materials by hydrodynamic cavitation processing was investigated. The goal of this work was to develop a general synthesis technique for nanostructured materials with a control over crystallite size in the 1--20 nm range. Materials with crystallite sizes in this range have shown enhanced catalytic activity compared to materials with larger crystallite sizes. Several supported and unsupported inorganic materials were studied to understand the effects of cavitation on crystallite size. Cavitation processing of calcium fluoride resulted in more spherical particles, attached to one another by melted necks. This work produced the first evidence of shock wave heating of nanostructured materials by hydrodynamic cavitation processing. Hydrodynamic cavitation synthesis of various catalytic support materials indicated that their phase composition and purity could be controlled by adjustment of the processing parameters. Zirconia/alumina supports synthesized using hydro-dynamic cavitation and calcined to 1368 K retained a high purity cubic zirconia phase, whereas classically prepared samples showed a phase transformation to monoclinic zirconia. Similarly, the synthesis of alumina resulted in materials with varying Bohmite and Bayerite contents as a function of the process parameters. High temperature calcination resulted in stable alumina supports with varying amounts of delta-, and theta-alumina. Synthesis studies of palladium and silver showed modest variations in crystallite size as a function of cavitation process parameters. Calcination resulted in larger grain materials, indicating a disappearance of intergrain boundaries. Based on these results, a new synthesis method was studied involving controlled agglomeration of small silver crystallites by hydrodynamic cavitation processing, followed by deposition on alumina. The optimal pH, concentration, and processing time for controlling the silver crystallite size in the cavitation equipment were determined using a statistical design of experiments approach. Three series of alumina supported silver catalysts were prepared, with silver weight loadings of 1%, 2%, and 5%. Variation of cavitation processing time between 1--64 min allowed the systematic control of silver crystallite size in the range of 3--19 nm. The preferred oxidation of CO in hydrogen (PROX) was chosen as a catalytic test reaction, because of its increasing importance for fuel cell applications. It was found that the catalytic activity was significantly increased for silver crystallite sizes below 5 nm. This work is the first experimental evidence of independent crystallite size control by hydrodynamic cavitation for alumina supported silver catalysts. The synthesis method involving controlled agglomeration and calcination is a general synthesis procedure that can be used to synthesize a wide range of novel catalysts and advanced materials.

  18. Hydrodynamic cavitation for sonochemical effects.

    PubMed

    Moholkar, V S; Kumar, P S; Pandit, A B

    1999-03-01

    A comparative study of hydrodynamic and acoustic cavitation has been made on the basis of numerical solutions of the Rayleigh-Plesset equation. The bubble/cavity behaviour has been studied under both acoustic and hydrodynamic cavitation conditions. The effect of varying pressure fields on the collapse of the cavity (sinusoidal for acoustic and linear for hydrodynamic) and also on the latter's dynamic behaviour has been studied. The variations of parameters such as initial cavity size, intensity of the acoustic field and irradiation frequency in the case of acoustic cavitation, and initial cavity size, final recovery pressure and time for pressure recovery in the case of hydrodynamic cavitation, have been found to have significant effects on cavity/bubble dynamics. The simulations reveal that the bubble/cavity collapsing behaviour in the case of hydrodynamic cavitation is accompanied by a large number of pressure pulses of relatively smaller magnitude, compared with just one or two pulses under acoustic cavitation. It has been shown that hydrodynamic cavitation offers greater control over operating parameters and the resultant cavitation intensity. Finally, a brief summary of the experimental results on the oxidation of aqueous KI solution with a hydrodynamic cavitation set-up is given which supports the conclusion of this numerical study. The methodology presented allows one to manipulate and optimise of specific process, either physical or chemical.

  19. A Non-catalytic Deep Desulphurization Process using Hydrodynamic Cavitation

    PubMed Central

    Suryawanshi, Nalinee B.; Bhandari, Vinay M.; Sorokhaibam, Laxmi Gayatri; Ranade, Vivek V.

    2016-01-01

    A novel approach is developed for desulphurization of fuels or organics without use of catalyst. In this process, organic and aqueous phases are mixed in a predefined manner under ambient conditions and passed through a cavitating device. Vapor cavities formed in the cavitating device are then collapsed which generate (in-situ) oxidizing species which react with the sulphur moiety resulting in the removal of sulphur from the organic phase. In this work, vortex diode was used as a cavitating device. Three organic solvents (n-octane, toluene and n-octanol) containing known amount of a model sulphur compound (thiophene) up to initial concentrations of 500 ppm were used to verify the proposed method. A very high removal of sulphur content to the extent of 100% was demonstrated. The nature of organic phase and the ratio of aqueous to organic phase were found to be the most important process parameters. The results were also verified and substantiated using commercial diesel as a solvent. The developed process has great potential for deep of various organics, in general, and for transportation fuels, in particular. PMID:27605492

  20. A Non-catalytic Deep Desulphurization Process using Hydrodynamic Cavitation.

    PubMed

    Suryawanshi, Nalinee B; Bhandari, Vinay M; Sorokhaibam, Laxmi Gayatri; Ranade, Vivek V

    2016-09-08

    A novel approach is developed for desulphurization of fuels or organics without use of catalyst. In this process, organic and aqueous phases are mixed in a predefined manner under ambient conditions and passed through a cavitating device. Vapor cavities formed in the cavitating device are then collapsed which generate (in-situ) oxidizing species which react with the sulphur moiety resulting in the removal of sulphur from the organic phase. In this work, vortex diode was used as a cavitating device. Three organic solvents (n-octane, toluene and n-octanol) containing known amount of a model sulphur compound (thiophene) up to initial concentrations of 500 ppm were used to verify the proposed method. A very high removal of sulphur content to the extent of 100% was demonstrated. The nature of organic phase and the ratio of aqueous to organic phase were found to be the most important process parameters. The results were also verified and substantiated using commercial diesel as a solvent. The developed process has great potential for deep of various organics, in general, and for transportation fuels, in particular.

  1. A Non-catalytic Deep Desulphurization Process using Hydrodynamic Cavitation

    NASA Astrophysics Data System (ADS)

    Suryawanshi, Nalinee B.; Bhandari, Vinay M.; Sorokhaibam, Laxmi Gayatri; Ranade, Vivek V.

    2016-09-01

    A novel approach is developed for desulphurization of fuels or organics without use of catalyst. In this process, organic and aqueous phases are mixed in a predefined manner under ambient conditions and passed through a cavitating device. Vapor cavities formed in the cavitating device are then collapsed which generate (in-situ) oxidizing species which react with the sulphur moiety resulting in the removal of sulphur from the organic phase. In this work, vortex diode was used as a cavitating device. Three organic solvents (n-octane, toluene and n-octanol) containing known amount of a model sulphur compound (thiophene) up to initial concentrations of 500 ppm were used to verify the proposed method. A very high removal of sulphur content to the extent of 100% was demonstrated. The nature of organic phase and the ratio of aqueous to organic phase were found to be the most important process parameters. The results were also verified and substantiated using commercial diesel as a solvent. The developed process has great potential for deep of various organics, in general, and for transportation fuels, in particular.

  2. An analysis of pump cavitation damage. [Space Shuttle main engine high pressure oxidizer turbopump

    NASA Technical Reports Server (NTRS)

    Brophy, M. C.; Stinebring, D. R.; Billet, M. L.

    1985-01-01

    The cavitation assessment for the space shuttle main engine high pressure oxidizer turbopump is documented. A model of the flow through the pump was developed. Initially, a computational procedure was used to analyze the flow through the inlet casing including the prediction of wakes downstream of the casing vanes. From these flow calculations, cavitation patterns on the inducer blades were approximated and the damage rate estimated. The model correlates the heavy damage on the housing and over the inducer with unsteady blade surface cavitation. The unsteady blade surface cavitation is due to the large incidence changes caused by the wakes of the upstream vanes. Very high cavitation damage rates are associated with this type of cavitation. Design recommendations for reducing the unsteady cavitation include removing the set of vanes closest to the inducer and modifying the remaining vanes.

  3. A study of pump cavitation damage. [space shuttle main engine high pressure oxidizer turbopump

    NASA Technical Reports Server (NTRS)

    Brophy, M. C.; Stinebring, D. R.; Billet, M. L.

    1983-01-01

    The cavitation assessment for the space shuttle main engine high pressure oxidizer turbopump is documented. A model of the flow through the pump was developed. Initially, a computational procedure was used to analyze the flow through the inlet casing including the prediction of wakes downstream of the casing vanes. From these flow calculations, cavitation patterns on the inducer blades were approximated and the damage rate estimated. The model correlates the heavy damage on the housing and over the inducer with unsteady blade surface cavitation. The unsteady blade surface cavitation is due to the large incidence changes caused by the wakes of the upstream vanes. Very high cavitation damage rates are associated with this type of cavitation. Design recommendations for reducing the unsteady cavitation include removing the set of vanes closest to the inducer and modifying the remaining vanes.

  4. Influence of Particle Size Distribution on the Morphology and Cavitation Resistance of High-Velocity Oxygen Fuel Coatings

    NASA Astrophysics Data System (ADS)

    Silveira, L. L.; Sucharski, G. B.; Pukasiewicz, A. G. M.; Paredes, R. S. C.

    2018-04-01

    The cavitation wear process is one of the major wear mechanisms in turbines and rotors of hydroelectric power plants in Brazil. An effective way to increase the cavitation resistance is the use of coatings, applied by thermal spraying. The high-velocity oxy-fuel process (HVOF) is one of the most used thermal spraying processes, and it is widely adopted for applying coatings for protection against wear and in maintenance components. A FeCrMnSiB experimental alloy was deposited onto SAE 1020 substrate by HVOF process, in order to evaluate the influence of the powder particle size range on the morphology and cavitation resistance of the coatings. The morphology of the coatings showed an increase in oxide content with powder size reduction. The increase in the powder particle size reduced the wettability of the particles, observed by the increase in the quantity of non-melted particles. Higher particle size distribution led to an increase in erosion rate, due to higher presence of non-melted particles in the coatings and consequently reduction of splats adhesion. The cavitation damage was perceived mainly by the mechanism of lamellae detachment; however, part of the damage was also absorbed by strain hardening due to the γ- ɛ martensitic transformation.

  5. Degradation of reactive orange 4 dye using hydrodynamic cavitation based hybrid techniques.

    PubMed

    Gore, Mohan M; Saharan, Virendra Kumar; Pinjari, Dipak V; Chavan, Prakash V; Pandit, Aniruddha B

    2014-05-01

    In the present work, degradation of reactive orange 4 dye (RO4) has been investigated using hydrodynamic cavitation (HC) and in combination with other AOP's. In the hybrid techniques, combination of hydrodynamic cavitation and other oxidizing agents such as H2O2 and ozone have been used to get the enhanced degradation efficiency through HC device. The hydrodynamic cavitation was first optimized in terms of different operating parameters such as operating inlet pressure, cavitation number and pH of the operating medium to get the maximum degradation of RO4. Following the optimization of HC parameters, the degradation of RO4 was carried out using the combination of HC with H2O2 and ozone. It has been found that the efficiency of the HC can be improved significantly by combining it with H2O2 and ozone. The mineralization rate of RO4 increases considerably with 14.67% mineralization taking place using HC alone increases to 31.90% by combining it with H2O2 and further increases to 76.25% through the combination of HC and ozone. The synergetic coefficient of greater than one for the hybrid processes of HC+H2O2 and HC+Ozone has suggested that the combination of HC with other oxidizing agents is better than the individual processes for the degradation of dye effluent containing RO4. The combination of HC with ozone proves to be the most energy efficient method for the degradation of RO4 as compared to HC alone and the hybrid process of HC and H2O2. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Ultrasonic cavitation erosion of 316L steel weld joint in liquid Pb-Bi eutectic alloy at 550°C.

    PubMed

    Lei, Yucheng; Chang, Hongxia; Guo, Xiaokai; Li, Tianqing; Xiao, Longren

    2017-11-01

    Liquid lead-bismuth eutectic alloy (LBE) is applied in the Accelerator Driven transmutation System (ADS) as the high-power spallation neutron targets and coolant. A 19.2kHz ultrasonic device was deployed in liquid LBE at 550°C to induce short and long period cavitation erosion damage on the surface of weld joint, SEM and Atomic force microscopy (AFM) were used to map out the surface properties, and Energy Dispersive Spectrometer (EDS) was applied to the qualitative and quantitative analysis of elements in the micro region of the surface. The erosion mechanism for how the cavitation erosion evolved by studying the element changes, their morphology evolution, the surface hardness and the roughness evolution, was proposed. The results showed that the pits, caters and cracks appeared gradually on the erode surface after a period of cavitation. The surface roughness increased along with exposure time. Work hardening by the bubbles impact in the incubation stage strengthened the cavitation resistance efficiently. The dissolution and oxidation corrosion and cavitation erosion that simultaneously happened in liquid LBE accelerated corrosion-erosion process, and these two processes combined to cause more serious damage on the material surface. Contrast to the performance of weld metal, base metal exhibited a much better cavitation resistance. Copyright © 2017. Published by Elsevier B.V.

  7. The cavitation induced Becquerel effect and the hot spot theory of sonoluminescence.

    PubMed

    Prevenslik, T V

    2003-06-01

    Over 150 years ago, Becquerel discovered the ultraviolet illumination of one of a pair of identical electrodes in liquid water produced an electric current, the phenomenon called the Becquerel effect. Recently, a similar effect was observed if the water surrounding one electrode is made to cavitate by focused acoustic radiation, which by similarity is referred to as the cavitation induced Becquerel effect. The current in the cavitation induced Becquerel effect was found to be semi-logarithmic with the standard electrode potential that is consistent with the oxidation of the electrode surface by the photo-decomposition theory of photoelectrochemistry. But oxidation of the electrode surface usually requires high temperatures, say as in cavitation. Absent high bubble temperatures, cavitation may produce vacuum ultraviolet (VUV) light that excites water molecules in the electrode film to higher H(2)O(*) energy states, the excited states oxidizing the electrode surface by chemical reaction. Solutions of the Rayleigh-Plesset equation during bubble collapse that include the condensation of water vapor show any increase in temperature or pressure of the water vapor by compression heating is compensated by the condensation of vapor to the bubble wall, the bubbles collapsing almost isothermally. Hence, the cavitation induced Becquerel effect is likely caused by cavitation induced VUV light at ambient temperature.

  8. Plastic deformation of a magnesium oxide 001-plane surface produced by cavitation

    NASA Technical Reports Server (NTRS)

    Hattori, S.; Miyoshi, K.; Buckley, D. H.; Okada, T.

    1986-01-01

    An investigation was conducted to examine plastic deformation of a cleaved single-crystal magnesium oxide 001-plane surface exposed to cavitation. Cavitation damage experiments were carried out in distilled water at 25 C by using a magnetostrictive oscillator in close proximity (2 mm) to the surface of the cleaved specimen. The dislocation-etch-pit patterns induced by cavitation were examined and compared with that of microhardness indentations. The results revealed that dislocation-etch-pit patterns around hardness indentations contain both screw and edge dislocations, while the etch-pit patterns on the surface exposed to cavitation contain only screw dislocations. During cavitation, deformation occurred in a thin surface layer, accompanied by work-hardening of the ceramic. The row of screw dislocations underwent a stable growth, which was analyzed crystallographically.

  9. Oxidation of alkylarenes to the corresponding acids using aqueous potassium permanganate by hydrodynamic cavitation.

    PubMed

    Ambulgekar, G V; Samant, S D; Pandit, A B

    2004-05-01

    Oxidation of toluene using aqueous potassium permanganate was studied under heterogeneous condition in the presence of hydrodynamic cavitation and compared with the results of the reaction under acoustic cavitation. Various parameters, such as quantity of potassium permanganate, toluene to aqueous phase ratio, reaction time and cavitation parameters such as orifice plate, and pump discharge pressure were optimized. The reaction was found to be considerably accelerated at ambient temperature in the presence of cavitation. On comparison, it was found that when 1 kJ of energy was passed to the reaction mixture in the case of acoustic cavitation, the product obtained was 4.63 x 10(-6) mol, whereas when 1 kJ of energy was passed to the reaction mixture in the case of hydrodynamic cavitation the product obtained was 2.70 x 10(-5) mol. Hence, about six times more product would be obtained in the case of hydrodynamic cavitation than in the case of acoustic cavitation at same energy dissipation. It has been observed that further optimization is possible.

  10. Cavitation During Superplastic Forming

    PubMed Central

    Campbell, John

    2011-01-01

    Cavitation is the opening of pores during superplastic forming, typically at grain boundary triple points or on second phase grain boundary particles during slip of grain boundaries. Theories for the initiation of cavitation are reviewed. It seems that cavitation is unlikely to occur by processes intrinsic to metals such as dislocation mechanisms or point defect condensation. It is proposed that cavitation can only occur at non-bonded interfaces such as those introduced extrinsically (i.e., from the outside) during the original casting of the metal. These defects, known as oxide bifilms, are naturally introduced during pouring of the liquid metal, and are frozen into the solid, often pushed by dendritic growth into grain boundaries where they are difficult to detect because of their extreme thinness, often measured in nanometres. Their unbonded central interface acts as a crack and can initiate cavitation. Second phase precipitates probably do not nucleate and grow on grain boundaries but grow on bifilms in the boundaries, explaining the apparent association between boundaries, second phase particles and failure initiation. Improved melting and casting techniques can provide metal with reduced or zero bifilm population for which cavitation would not be possible, promising significant improvements in superplastic behaviour. PMID:28824142

  11. Cavitation During Superplastic Forming.

    PubMed

    Campbell, John

    2011-07-08

    Cavitation is the opening of pores during superplastic forming, typically at grain boundary triple points or on second phase grain boundary particles during slip of grain boundaries. Theories for the initiation of cavitation are reviewed. It seems that cavitation is unlikely to occur by processes intrinsic to metals such as dislocation mechanisms or point defect condensation. It is proposed that cavitation can only occur at non-bonded interfaces such as those introduced extrinsically (i.e., from the outside) during the original casting of the metal. These defects, known as oxide bifilms, are naturally introduced during pouring of the liquid metal, and are frozen into the solid, often pushed by dendritic growth into grain boundaries where they are difficult to detect because of their extreme thinness, often measured in nanometres. Their unbonded central interface acts as a crack and can initiate cavitation. Second phase precipitates probably do not nucleate and grow on grain boundaries but grow on bifilms in the boundaries, explaining the apparent association between boundaries, second phase particles and failure initiation. Improved melting and casting techniques can provide metal with reduced or zero bifilm population for which cavitation would not be possible, promising significant improvements in superplastic behaviour.

  12. Efficient inactivation of MS-2 virus in water by hydrodynamic cavitation.

    PubMed

    Kosel, Janez; Gutiérrez-Aguirre, Ion; Rački, Nejc; Dreo, Tanja; Ravnikar, Maja; Dular, Matevž

    2017-11-01

    The aim of this study was to accurately quantify the impact of hydrodynamic cavitation on the infectivity of bacteriophage MS2, a norovirus surrogate, and to develop a small scale reactor for testing the effect of hydrodynamic cavitation on human enteric viruses, which cannot be easily prepared in large quantities. For this purpose, 3 mL scale and 1 L scale reactors were constructed and tested. Both devices were efficient in generating hydrodynamic cavitation and in reducing the infectivity of MS2 virus. Furthermore, they reached more than 4 logs reductions of viral infectivity, thus confirming the scalability of hydrodynamic cavitation for this particular application. As for the mechanism of page inactivation, we suspect that cavitation generated OH - radicals formed an advanced oxidation process, which could have damaged the host's recognition receptors located on the surface of the bacteriophage. Additional damage could arise from the high shear forces inside the cavity. Moreover, the effectiveness of the cavitation was higher for suspensions containing low initial viral titers that are in similar concentration to the ones found in real water samples. According to this, cavitation generators could prove to be a useful tool for treating virus-contaminated wastewaters in the future. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Analysis of cavitation damage on the Space Shuttle main engine high pressure oxidizer turbopump

    NASA Technical Reports Server (NTRS)

    Stinebring, D. R.

    1985-01-01

    The performance of the Space Shuttle Main Engines (SSME) has met or exceeded specifications. However, the durability for selected components has not met the desired lifetime criteria. Thus, the High-Pressure Oxidizer Turbopump (HPOTP) has experienced cavitation erosion problems in a number of locations in the pump. An investigation was conducted, taking into account an analysis of the cavitation damage, the development of a flow model for the pump, and the recommendation of design changes which would increase the life expectancy of the unit. The present paper is concerned with the cavitation damage analysis. A model is presented which relates the heavy damage on the housing and over the inducer blades to unsteady blade surface cavitation. This cavitation occurs on the inducer blades in the wakes downstream of the pump inlet housing vanes.

  14. Water Flow Testing and Unsteady Pressure Analysis of a Two-Bladed Liquid Oxidizer Pump Inducer

    NASA Technical Reports Server (NTRS)

    Schwarz, Jordan B.; Mulder, Andrew; Zoladz, Thomas

    2011-01-01

    The unsteady fluid dynamic performance of a cavitating two-bladed oxidizer turbopump inducer was characterized through sub-scale water flow testing. While testing a novel inlet duct design that included a cavitation suppression groove, unusual high-frequency pressure oscillations were observed. With potential implications for inducer blade loads, these high-frequency components were analyzed extensively in order to understand their origins and impacts to blade loading. Water flow testing provides a technique to determine pump performance without the costs and hazards associated with handling cryogenic propellants. Water has a similar density and Reynolds number to liquid oxygen. In a 70%-scale water flow test, the inducer-only pump performance was evaluated. Over a range of flow rates, the pump inlet pressure was gradually reduced, causing the flow to cavitate near the pump inducer. A nominal, smooth inducer inlet was tested, followed by an inlet duct with a circumferential groove designed to suppress cavitation. A subsequent 52%-scale water flow test in another facility evaluated the combined inducer-impeller pump performance. With the nominal inlet design, the inducer showed traditional cavitation and surge characteristics. Significant bearing loads were created by large side loads on the inducer during synchronous cavitation. The grooved inlet successfully mitigated these loads by greatly reducing synchronous cavitation, however high-frequency pressure oscillations were observed over a range of frequencies. Analytical signal processing techniques showed these oscillations to be created by a rotating, multi-celled train of pressure pulses, and subsequent CFD analysis suggested that such pulses could be created by the interaction of rotating inducer blades with fluid trapped in a cavitation suppression groove. Despite their relatively low amplitude, these high-frequency pressure oscillations posed a design concern due to their sensitivity to flow conditions and test scale. The amplitude and frequency of oscillations varied considerably over the pump s operating space, making it difficult to predict blade loads.

  15. Degradation of imidacloprid using combined advanced oxidation processes based on hydrodynamic cavitation.

    PubMed

    Patil, Pankaj N; Bote, Sayli D; Gogate, Parag R

    2014-09-01

    The harmful effects of wastewaters containing pesticides or insecticides on human and aquatic life impart the need of effectively treating the wastewater streams containing these contaminants. In the present work, hydrodynamic cavitation reactors have been applied for the degradation of imidacloprid with process intensification studies based on different additives and combination with other similar processes. Effect of different operating parameters viz. concentration (20-60 ppm), pressure (1-8 bar), temperature (34 °C, 39 °C and 42 °C) and initial pH (2.5-8.3) has been investigated initially using orifice plate as cavitating device. It has been observed that 23.85% degradation of imidacloprid is obtained at optimized set of operating parameters. The efficacy of different process intensifying approaches based on the use of hydrogen peroxide (20-80 ppm), Fenton's reagent (H2O2:FeSO4 ratio as 1:1, 1:2, 2:1, 2:2, 4:1 and 4:2), advanced Fenton process (H2O2:Iron Powder ratio as 1:1, 2:1 and 4:1) and combination of Na2S2O8 and FeSO4 (FeSO4:Na2S2O8 ratio as 1:1, 1:2, 1:3 and 1:4) on the extent of degradation has been investigated. It was observed that near complete degradation of imidacloprid was achieved in all the cases at optimized values of process intensifying parameters. The time required for complete degradation of imidacloprid for approach based on hydrogen peroxide was 120 min where as for the Fenton and advance Fenton process, the required time was only 60 min. To check the effectiveness of hydrodynamic cavitation with different cavitating devices, few experiments were also performed with the help of slit venturi as a cavitating device at already optimized values of parameters. The present work has conclusively established that combined processes based on hydrodynamic cavitation can be effectively used for complete degradation of imidacloprid. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Enhanced decolorization of methyl orange using zero-valent copper nanoparticles under assistance of hydrodynamic cavitation.

    PubMed

    Li, Pan; Song, Yuan; Wang, Shuai; Tao, Zheng; Yu, Shuili; Liu, Yanan

    2015-01-01

    The rate of reduction reactions of zero-valent metal nanoparticles is restricted by their agglomeration. Hydrodynamic cavitation was used to overcome the disadvantage in this study. Experiments for decolorization of methyl orange azo dye by zero-valent copper nanoparticles were carried out in aqueous solution with and without hydrodynamic cavitation. The results showed that hydrodynamic cavitation greatly accelerated the decolorization rate of methyl orange. The size of nanoparticles was decreased after hydrodynamic cavitation treatment. The effects of important operating parameters such as discharge pressure, initial solution pH, and copper nanoparticle concentration on the degradation rates were studied. It was observed that there was an optimum discharge pressure to get best decolorization performance. Lower solution pH were favorable for the decolorization. The pseudo-first-order kinetic constant for the degradation of methyl orange increased linearly with the copper dose. UV-vis spectroscopic and Fourier transform infrared (FT-IR) analyses confirmed that many degradation intermediates were formed. The results indicated hydroxyl radicals played a key role in the decolorization process. Therefore, the enhancement of decolorization by hydrodynamic cavitation could due to the deagglomeration of nanoparticles as well as the oxidation by the in situ generated hydroxyl radicals. These findings greatly increase the potential of the Cu(0)/hydrodynamic cavitation technique for use in the field of treatment of wastewater containing hazardous materials. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Treatment of industrial wastewater effluents using hydrodynamic cavitation and the advanced Fenton process.

    PubMed

    Chakinala, Anand G; Gogate, Parag R; Burgess, Arthur E; Bremner, David H

    2008-01-01

    For the first time, hydrodynamic cavitation induced by a liquid whistle reactor (LWR) has been used in conjunction with the advanced Fenton process (AFP) for the treatment of real industrial wastewater. Semi-batch experiments in the LWR were designed to investigate the performance of the process for two different industrial wastewater samples. The effect of various operating parameters such as pressure, H2O2 concentration and the initial concentration of industrial wastewater samples on the extent of mineralization as measured by total organic carbon (TOC) content have been studied with the aim of maximizing the extent of degradation. It has been observed that higher pressures, sequential addition of hydrogen peroxide at higher loadings and lower concentration of the effluent are more favourable for a rapid TOC mineralization. In general, the novel combination of hydrodynamic cavitation with AFP results in about 60-80% removal of TOC under optimized conditions depending on the type of industrial effluent samples. The combination described herein is most useful for treatment of bio-refractory materials where the diminution in toxicity can be achieved up to a certain level and then conventional biological oxidation can be employed for final treatment. The present work is the first to report the use of a hydrodynamic cavitation technique for real industrial wastewater treatment.

  18. Treatment of persistent organic pollutants in wastewater using hydrodynamic cavitation in synergy with advanced oxidation process.

    PubMed

    Badmus, Kassim Olasunkanmi; Tijani, Jimoh Oladejo; Massima, Emile; Petrik, Leslie

    2018-03-01

    Persistent organic pollutants (POPs) are very tenacious wastewater contaminants. The consequences of their existence have been acknowledged for negatively affecting the ecosystem with specific impact upon endocrine disruption and hormonal diseases in humans. Their recalcitrance and circumvention of nearly all the known wastewater treatment procedures are also well documented. The reported successes of POPs treatment using various advanced technologies are not without setbacks such as low degradation efficiency, generation of toxic intermediates, massive sludge production, and high energy expenditure and operational cost. However, advanced oxidation processes (AOPs) have recently recorded successes in the treatment of POPs in wastewater. AOPs are technologies which involve the generation of OH radicals for the purpose of oxidising recalcitrant organic contaminants to their inert end products. This review provides information on the existence of POPs and their effects on humans. Besides, the merits and demerits of various advanced treatment technologies as well as the synergistic efficiency of combined AOPs in the treatment of wastewater containing POPs was reported. A concise review of recently published studies on successful treatment of POPs in wastewater using hydrodynamic cavitation technology in combination with other advanced oxidation processes is presented with the highlight of direction for future research focus.

  19. The effect of chloride ions on the corroded surface layer of 00Cr22Ni5Mo3N duplex stainless steel under cavitation.

    PubMed

    Wan, Tong; Xiao, Ning; Shen, Hanjie; Yong, Xingyue

    2016-11-01

    The effects of Cl(-) on the corroded surface layer of 00Cr22Ni5Mo3N duplex stainless steel under cavitation in chloride solutions were investigated using nanoindentation in conjunction with XRD and XPS. The results demonstrate that Cl(-) had a strong effect on the nano-mechanical properties of the corroded surface layer under cavitation, and there was a threshold Cl(-) concentration. Furthermore, a close relationship between the nano-mechanical properties and the cavitation corrosion resistance of 00Cr22Ni5Mo3N duplex stainless steel was observed. The degradation of the nano-mechanical properties of the corroded surface layer was accelerated by the synergistic effect between cavitation erosion and corrosion. A key factor was the adsorption of Cl(-), which caused a preferential dissolution of the ferrous oxides in the passive film layer on the corroded surface layer. Cavitation further promoted the preferential dissolution of the ferrous oxides in the passive film layer. Simultaneously, cavitation accelerated the erosion of the ferrite in the corroded surface layer, resulting in the degradation of the nano-mechanical properties of the corroded surface layer on 00Cr22Ni5Mo3N duplex stainless steel under cavitation. Copyright © 2016. Published by Elsevier B.V.

  20. Decolourization of Rhodamine B: A swirling jet-induced cavitation combined with NaOCl.

    PubMed

    Mancuso, Giuseppe; Langone, Michela; Laezza, Marco; Andreottola, Gianni

    2016-09-01

    A hydrodynamic cavitation reactor (Ecowirl) based on swirling jet-induced cavitation has been used in order to allow the degradation of a waste dye aqueous solution (Rhodamine B, RhB). Cavitation generated by Ecowirl reactor was directly compared with cavitation generated by using multiple hole orifice plates. The effects of operating conditions and parameters such as pressure, pH of dye solution, initial concentration of RhB and geometry of the cavitating devices on the degradation rate of RhB were discussed. In similar operative conditions, higher extents of degradation (ED) were obtained using Ecowirl reactor rather than orifice plate. An increase in the ED from 8.6% to 14.7% was observed moving from hole orifice plates to Ecowirl reactor. Intensification in ED of RhB by using hydrodynamic cavitation in presence of NaOCl as additive has been studied. It was found that the decolourization was most efficient for the combination of hydrodynamic cavitation and chemical oxidation as compared to chemical oxidation and hydrodynamic cavitation alone. The value of ED of 83.4% was reached in 37min using Ecowirl combined with NaOCl (4.0mgL(-1)) as compared to the 100min needed by only mixing NaOCl at the same concentration. At last, the energetic consumptions of the cavitation devices have been evaluated. Increasing the ED and reducing the treatment time, Ecowirl reactor resulted to be more energy efficient as compared to hole orifice plates, Venturi and other swirling jet-induced cavitation devices, as reported in literature. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Decontamination of unsymmetrical dimethylhydrazine waste water by hydrodynamic cavitation-induced advanced Fenton process.

    PubMed

    Torabi Angaji, Mahmood; Ghiaee, Reza

    2015-03-01

    A pilot scale hydrodynamic cavitation (HC) reactor, using iron metal blades, as the heterogeneous catalyst, with no external source of H₂O₂ was developed for catalytic decontamination of unsymmetrical dimethylhydrazine (UDMH) waste water. In situ generation of Fenton reagents suggested an induced advanced Fenton process (IAFP) to explain the enhancing effect of the used catalyst in the HC process. The effects of the applied catalyst, pH of the initial solution (1.0-9.7), initial UDMH concentration (2-15 mg/l), inlet pressure (5.5-7.8bar), and downstream pressure (2-6 bar), have been investigated. The results showed that the highest cavitation yield can be obtained at pH 3 and initial UDMH concentration of 10mg/l. Also, an increase in the inlet pressure would lead to an increase in the extent of UDMH degradation. In addition, the optimum value of 3 bar was determined for the downstream pressure that resulted to 98.6% degradation of UDMH after 120 min of processing time. Neither n-nitrosodimethylamine (NDMA) nor any other toxic byproduct (/end-product) was observed in the investigated samples. Formic acid and acetic acid, as well as nitromethane, were identified as oxidation by-products. The present work has conclusively established that hydrodynamic cavitation in combination with Fenton's chemistry can be effectively used for the degradation of UDMH. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. A study of pump cavitation damage

    NASA Astrophysics Data System (ADS)

    Brophy, M. C.; Stinebring, D. R.; Billet, M. L.

    1983-11-01

    The cavitation assessment for the space shuttle main engine high pressure oxidizer turbopump is documented. A model of the flow through the pump was developed. Initially, a computational procedure was used to analyze the flow through the inlet casing including the prediction of wakes downstream of the casing vanes. From these flow calculations, cavitation patterns on the inducer blades were approximated and the damage rate estimated. The model correlates the heavy damage on the housing and over the inducer with unsteady blade surface cavitation. The unsteady blade surface cavitation is due to the large incidence changes caused by the wakes of the upstream vanes. Very high cavitation damage rates are associated with this type of cavitation. Design recommendations for reducing the unsteady cavitation include removing the set of vanes closest to the inducer and modifying the remaining vanes.

  3. Degradation of a cationic dye (Rhodamine 6G) using hydrodynamic cavitation coupled with other oxidative agents: Reaction mechanism and pathway.

    PubMed

    Rajoriya, Sunil; Bargole, Swapnil; Saharan, Virendra Kumar

    2017-01-01

    In the present study, decolorization and mineralization of a cationic dye, Rhodamine 6G (Rh6G), has been carried out using hydrodynamic cavitation (HC). Two cavitating devices such as slit and circular venturi were used to generate cavitation in HC reactor. The process parameters such as initial dye concentration, solution pH, operating inlet pressure, and cavitation number were investigated in detail to evaluate their effects on the decolorization efficiency of Rh6G. Decolorization of Rh6G was marginally higher in the case of slit venturi as compared to circular venturi. The kinetic study showed that decolorization and mineralization of the dye fitted first-order kinetics. The loadings of H 2 O 2 and ozone have been optimized to intensify the decolorization and mineralization efficiency of Rh6G using HC. Nearly 54% decolorization of Rh6G was obtained using a combination of HC and H 2 O 2 at a dye to H 2 O 2 molar ratio of 1:30. The combination of HC with ozone resulted in 100% decolorization in almost 5-10min of processing time depending upon the initial dye concentration. To quantify the extent of mineralization, total organic carbon (TOC) analysis was also performed using various processes and almost 84% TOC removal was obtained using HC coupled with 3g/h of ozone. The degradation by-products formed during the complete degradation process were qualitatively identified by liquid chromatography-mass spectrometry (LC-MS) and a detailed degradation pathway has been proposed. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Hydrodynamic cavitation in combination with the ozone, hydrogen peroxide and the UV-based advanced oxidation processes for the removal of natural organic matter from drinking water.

    PubMed

    Čehovin, Matej; Medic, Alojz; Scheideler, Jens; Mielcke, Jörg; Ried, Achim; Kompare, Boris; Žgajnar Gotvajn, Andreja

    2017-07-01

    Natural organic matter in drinking water is causing concern especially due to the formation of disinfection by-products (DBPs) by chlorine, as these are proven to have adverse health effects on consumers. In this research, humic acid was used as a source of dissolved organic carbon (DOC) in drinking water (up to 3mgL -1 ). The efficiency of DOC removal was studied by applying O 3 , H 2 O 2 /O 3 , H 2 O 2 /UV and O 3 /UV advanced oxidation processes (AOPs) alone and combined with hybrid hydrodynamic cavitation (HC), generated by an orifice plate, as this technology recently shows promising potential for the treatment of water, containing recalcitrant organic substances. It was observed that the combined treatment by HC could significantly affect the performance of the applied AOPs, with as little as 3-9 passes through the cavitation generators. For O 3 and H 2 O 2 dosages up to 2 and 4mgL -1 , respectively, and UV dosage up to 300mJcm -2 , HC enhanced DOC removal by 5-15% in all combinations, except for O 3 /UV AOPs. Overall, the potential benefits of HC for DOC removal were emphasized for low ratio between applied oxidants to DOC and high UV absorbance of the sample. Investigated DBPs formation potentials require special attention for H 2 O 2 /UV AOPs and combinations with HC. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. A novel device for hazardous substances degradation based on double-cavitating-jets impingement: Parameters optimization and efficiency assessment.

    PubMed

    Tao, Yuequn; Cai, Jun; Huai, Xiulan; Liu, Bin

    2017-08-05

    Hydrodynamic cavitation is an effective advanced oxidation process. But sometimes it cannot obtain satisfactory treatment efficiency by using hydrodynamic cavitation individually, so it is necessary to introduce intensive methods. Based on double-cavitating-jets impingement, this paper presents a novel device that has advantages of strong heat and mass transfer and efficient chemical reactions. Based on the device, a series of experimental investigations on degradation of a basic dye, i.e. Rhodamine B were carried out. Significant Rhodamine B removal from aqueous solution was observed during 2h treatment and the degradation reaction conformed to pseudo-first-order kinetics. The synergetic effects between double-cavitating-jets impingement and Fenton chemistry on simultaneous degradation of Rhodamine B were confirmed. Both single-variable experiments and orthogonal experiments were carried out to study the effects of initial hydrogen peroxide, ferrous sulfate and Rhodamine B concentrations and the optimum conditions were found out. Effects of jet inlet pressure in the range of 6-12MPa and solution pH value in the range of 2-8 were also investigated. The cavitation yield was evaluated to assess the energy efficiency. The present treatment scheme showed advantages in terms of reducing the demand of hydrogen peroxide concentration and enhancing the treatment efficiency in large scale operation. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Removing Fats, Oils and Greases from Grease Trap by Hybrid AOPs (Ozonation and Sonication)

    NASA Astrophysics Data System (ADS)

    Kwiatkowski, Michal Piotr; Satoh, Saburoh; Yamabe, Chobei; Ihara, Satoshi; Nieda, Masanori

    The purpose of this study was to investigate the electrical energy for the environmental applications using AOPs (advanced oxidation processes) combined with ozonation and sonication to remove the FOG (fats, oils and greases) from wastewater of the sewage system. This study focused on FOG removal from a grease trap using the hybrid AOPs. Fatty acids (linoleic, oleic, stearic and palmitic acids) were used as representative standards of FOG. The studies were conducted experimentally in a glass reactor under various operational conditions. The oxidation efficiency using the combination of the ozonation and sonication was determined by the KI dosimetry method and the calorimetry method. Fatty acids concentration were measured by GC/MS. The local reaction field of the high temperature and high pressure, so-called hot spot, was generated by the quasi-adiabatic collapse of bubbles produced in the water under sonication, which is called cavitation phenomenon. Mixing the ozone bubbles into the water under acoustic cavitation, the formation of OH radicals increased. The mechanical effect of acoustic cavitation such as microstreaming and shock waves have an influence on the probability of reactions of ozone and radicals with fatty acids.

  7. Deformation processes in forging ceramics

    NASA Technical Reports Server (NTRS)

    Cannon, R. M.; Rhodes, W. H.

    1972-01-01

    The deformation processes involved in the forging of refractory ceramic oxides were investigated. A combination of mechanical testing and forging are utilized to investigate both the flow and fracture processes involved. An additional hemisphere forging was done which failed prematurely. Analysis and comparison with available fracture data for AL2O3 indicated possible causes of the failure. Examination of previous forgings indicated an increase in grain boundary cavitation with increasing strain.

  8. Investigation of characteristics of feed system instabilities

    NASA Technical Reports Server (NTRS)

    Vaage, R. D.; Fidler, L. E.; Zehnle, R. A.

    1972-01-01

    The relationship between the structural and feed system natural frequencies in structure-propulsion system coupled longitudinal oscillations (pogo) is investigated. The feed system frequencies are usually very dependent upon the compressibility (compliance) of cavitation bubbles that exist to some extent in all operating turbopumps. This document includes: a complete review of cavitation mechanisms; development of a turbopump cavitation compliance model; an accumulation and analysis of all available cavitation compliance test data; and a correlation of empirical-analytical results. The analytical model is based on the analysis of flow relative to a set of cascaded blades, having any described shape, and assumes phase changes occur under conditions of isentropic equilibrium. Analytical cavitation compliance predictions for the J-2 LOX, F-1 LOX, H-1 LOX and LR87 oxidizer turbopump inducers do not compare favorably with test data. The model predicts much less cavitation than is derived from the test data. This implies that mechanisms other than blade cavitation contribute significantly to the total amount of turbopump cavitation.

  9. Characterization of Axial Inducer Cavitation Instabilities via High Speed Video Recordings

    NASA Technical Reports Server (NTRS)

    Arellano, Patrick; Peneda, Marinelle; Ferguson, Thomas; Zoladz, Thomas

    2011-01-01

    Sub-scale water tests were undertaken to assess the viability of utilizing high resolution, high frame-rate digital video recordings of a liquid rocket engine turbopump axial inducer to characterize cavitation instabilities. These high speed video (HSV) images of various cavitation phenomena, including higher order cavitation, rotating cavitation, alternating blade cavitation, and asymmetric cavitation, as well as non-cavitating flows for comparison, were recorded from various orientations through an acrylic tunnel using one and two cameras at digital recording rates ranging from 6,000 to 15,700 frames per second. The physical characteristics of these cavitation forms, including the mechanisms that define the cavitation frequency, were identified. Additionally, these images showed how the cavitation forms changed and transitioned from one type (tip vortex) to another (sheet cavitation) as the inducer boundary conditions (inlet pressures) were changed. Image processing techniques were developed which tracked the formation and collapse of cavitating fluid in a specified target area, both in the temporal and frequency domains, in order to characterize the cavitation instability frequency. The accuracy of the analysis techniques was found to be very dependent on target size for higher order cavitation, but much less so for the other phenomena. Tunnel-mounted piezoelectric, dynamic pressure transducers were present throughout these tests and were used as references in correlating the results obtained by image processing. Results showed good agreement between image processing and dynamic pressure spectral data. The test set-up, test program, and test results including H-Q and suction performance, dynamic environment and cavitation characterization, and image processing techniques and results will be discussed.

  10. Dependence of cavitation, chemical effect, and mechanical effect thresholds on ultrasonic frequency.

    PubMed

    Thanh Nguyen, Tam; Asakura, Yoshiyuki; Koda, Shinobu; Yasuda, Keiji

    2017-11-01

    Cavitation, chemical effect, and mechanical effect thresholds were investigated in wide frequency ranges from 22 to 4880kHz. Each threshold was measured in terms of sound pressure at fundamental frequency. Broadband noise emitted from acoustic cavitation bubbles was detected by a hydrophone to determine the cavitation threshold. Potassium iodide oxidation caused by acoustic cavitation was used to quantify the chemical effect threshold. The ultrasonic erosion of aluminum foil was conducted to estimate the mechanical effect threshold. The cavitation, chemical effect, and mechanical effect thresholds increased with increasing frequency. The chemical effect threshold was close to the cavitation threshold for all frequencies. At low frequency below 98kHz, the mechanical effect threshold was nearly equal to the cavitation threshold. However, the mechanical effect threshold was greatly higher than the cavitation threshold at high frequency. In addition, the thresholds of the second harmonic and the first ultraharmonic signals were measured to detect bubble occurrence. The threshold of the second harmonic approximated to the cavitation threshold below 1000kHz. On the other hand, the threshold of the first ultraharmonic was higher than the cavitation threshold below 98kHz and near to the cavitation threshold at high frequency. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Investigations of effect of phase change mass transfer rate on cavitation process with homogeneous relaxation model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    He, Zhixia; Zhang, Liang; Saha, Kaushik

    The super high fuel injection pressure and micro size of nozzle orifice has been an important development trend for the fuel injection system. Accordingly, cavitation transient process, fuel compressibility, amount of noncondensable gas in the fuel and cavitation erosion have attracted more attention. Based on the fact of cavitation in itself is a kind of thermodynamic phase change process, this paper takes the perspective of the cavitation phase change mass transfer process to analyze above mentioned phenomenon. The two-phase cavitating turbulent flow simulations with VOF approach coupled with HRM cavitation model and U-RANS of standard k-ε turbulence model were performedmore » for investigations of cavitation phase change mass transfer process. It is concluded the mass transfer time scale coefficient in the Homogenous Relaxation Model (HRM) representing mass transfer rate should tend to be as small as possible in a condition that ensured the solver stable. At very fast mass transfer rate, the phase change occurs at very thin interface between liquid and vapor phase and condensation occurs more focused and then will contribute predictably to a more serious cavitation erosion. Both the initial non-condensable gas in fuel and the fuel compressibility can accelerate the cavitation mass transfer process.« less

  12. Acoustic Cavitation Studies

    DTIC Science & Technology

    1981-09-01

    were made of the acoustic cavitation threshold as a function of polymer concentration for additives such as guar gum and polyethelene oxide. The...of California P.O. Box 808 Livermore, California 94550 Harry Diamond Laboratories I copy Technical Library 2800 Powder Mill Road Adelphi, Maryland

  13. Grain boundary oxidation and its effects on high temperature fatigue life

    NASA Technical Reports Server (NTRS)

    Liu, H. W.; Oshida, Yoshiki

    1986-01-01

    Fatigue lives at elevated temperatures are often shortened by creep and/or oxidation. Creep causes grain boundary void nucleation and grain boundary cavitation. Grain boundary voids and cavities will accelerate fatigue crack nucleation and propagation, and thereby shorten fatigue life. The functional relationships between the damage rate of fatigue crack nucleation and propagation and the kinetic process of oxygen diffusion depend on the detailed physical processes. The kinetics of grain boundary oxidation penetration was investigated. The statistical distribution of grain boundary penetration depth was analyzed. Its effect on high temperature fatigue life are discussed. A model of intermittent micro-ruptures of grain boundary oxide was proposed for high temperature fatigue crack growth. The details of these studies are reported.

  14. Effect of Applied Current Density on Cavitation-Erosion Characteristics for Anodized Al Alloy.

    PubMed

    Lee, Seung-Jun; Kim, Seong-Jong

    2018-02-01

    Surface finishing is as important as selection of material to achieve durability. Surface finishing is a process to provide surface with the desired performance and features by applying external forces such as thermal energy or stress. This study investigated the optimum supply current density for preventing from cavitation damages by applying to an anodizing technique that artificially forms on the surface an oxide coating that has excellent mechanical characteristics, such as hardness, wear resistance. Result of hardness test, the greater hardness was associated with greater brittleness, resulting in deleterious characteristics. Consequently, under conditions such as the electrolyte concentration of 10 vol.%, the processing time of 40 min, the electrolyte temperature of 10 °C, and the current density of 20 mA/cm2 were considered to be the optimum anodizing conditions for improvement of durability in seawater.

  15. Study of Traverse Speed Effects on Residual Stress State and Cavitation Erosion Behavior of Arc-Sprayed Aluminum Bronze Coatings

    NASA Astrophysics Data System (ADS)

    Hauer, Michél; Henkel, Knuth Michael; Krebs, Sebastian; Kroemmer, Werner

    2017-01-01

    Within a research project regarding cavitation erosion-resistant coatings, arc spraying was used with different traverse speeds to influence heat transfer and the resulting residual stress state. The major reason for this study is the lack of knowledge concerning the influence of residual stress distribution on mechanical properties and coating adhesion, especially with respect to heterogeneous aluminum bronze alloys. The materials used for spray experiments were the highly cavitation erosion-resistant propeller alloys CuAl9Ni5Fe4Mn (Ni-Al-Bronze) and CuMn13Al8Fe3Ni2 (Mn-Al-Bronze). Analyses of cavitation erosion behavior were carried out to evaluate the suitability for use in marine environments. Further microstructural, chemical and mechanical analyses were realized to examine adhesive and cohesive coating properties. Residual stress distribution was measured by modified hole drilling method using electronic speckle pattern interferometry (ESPI). It was found that the highest traverse speed led to higher tensile residual stresses near the surface and less cavitation erosion resistance of the coatings. Moreover, high oxygen affinity of main alloying element aluminum was identified to severely influence the microstructures by the formation of large oxides and hence the coating properties. Overall, Mn-Al-Bronze coatings showed lower residual stresses, a more homogeneous pore and oxide distribution and less material loss by cavitation than Ni-Al-Bronze coatings.

  16. Warm Spraying of High-Strength Ni-Al-Bronze: Cavitation Characteristics and Property Prediction

    NASA Astrophysics Data System (ADS)

    Krebs, Sebastian; Kuroda, Seiji; Katanoda, Hiroshi; Gaertner, Frank; Klassen, Thomas; Araki, Hiroshi; Frede, Simon

    2017-01-01

    Bronze materials such as Ni-Al-bronze show exceptional performances against cavitation erosion, due to their high fatigue strength and high strength. These materials are used for ship propellers, pump systems or for applications with alternating stresses. Usually, the respective parts are cast. With the aim to use resources more efficiently and to reduce costs, this study aimed to evaluate opportunities to apply bronze as a coating to critical areas of respective parts. The coatings should have least amounts of pores and non-bonded areas and any contaminations that might act as crack nuclei and contribute to material damages. Processes with low oxidation and high kinetic impacts fulfill these criteria. Especially warm spraying, a nitrogen-cooled HVOF process, with similar impact velocities as cold gas spraying but enhanced process temperature, allows for depositing high-strength Ni-Al-bronze. This study systematically simulates and evaluates the formation and performance of warm-sprayed Ni-Al-bronze coatings for different combustion pressures and nitrogen flow rates. Substrate preheating was used to improve coating adhesion for lower spray parameter sets. Furthermore, this study introduces an energy-based concept to compare spray parameter sets and to predict coating properties. Coatings with low porosities and high mechanical strengths are obtained, allowing for a cavitation resistance similar to bulk material.

  17. A theoretical study of hydrodynamic cavitation.

    PubMed

    Arrojo, S; Benito, Y

    2008-03-01

    The optimization of hydrodynamic cavitation as an AOP requires identifying the key parameters and studying their effects on the process. Specific simulations of hydrodynamic bubbles reveal that time scales play a major role on the process. Rarefaction/compression periods generate a number of opposing effects which have demonstrated to be quantitatively different from those found in ultrasonic cavitation. Hydrodynamic cavitation can be upscaled and offers an energy efficient way of generating cavitation. On the other hand, the large characteristic time scales hinder bubble collapse and generate a low number of cavitation cycles per unit time. By controlling the pressure pulse through a flexible cavitation chamber design these limitations can be partially compensated. The chemical processes promoted by this technique are also different from those found in ultrasonic cavitation. Properties such as volatility or hydrophobicity determine the potential applicability of HC and therefore have to be taken into account.

  18. Cavitation Generation and Usage Without Ultrasound: Hydrodynamic Cavitation

    NASA Astrophysics Data System (ADS)

    Gogate, Parag R.; Pandit, Aniruddha B.

    Hydrodynamic Cavitation, which was and is still looked upon as an unavoidable nuisance in the flow systems, can be a serious contender as an alternative to acoustic cavitation for harnessing the spectacular effects of cavitation in physical and chemical processing. The present chapter covers the basics of hydrodynamic cavitation including the considerations for the bubble dynamics analysis, reactor designs and recommendations for optimum operating parameters. An overview of applications in different areas of physical, chemical and biological processing on scales ranging from few grams to several hundred kilograms has also been presented. Since hydrodynamic cavitation was initially proposed as an alternative to acoustic cavitation, it is necessary to compare the efficacy of both these modes of cavitations for a variety of applications and hence comparisons have been discussed either on the basis of energy efficiency or based on the scale of operation. Overall it appears that hydrodynamic cavitation results in conditions similar to those generated using acoustic cavitation but at comparatively much larger scale of operation and with better energy efficiencies.

  19. Acoustic cavitation studies

    NASA Astrophysics Data System (ADS)

    Crum, L. A.

    1981-09-01

    The primary thrust of this study was toward a more complete understanding of general aspects of acoustic cavitation. The effect of long-chain polymer additives on the cavitation threshold was investigated to determine if they reduced the acoustic cavitation threshold in a similar manner to the observed reduction in the cavitation index in hydrodynamic cavitation. Measurements were made of the acoustic cavitation threshold as a function of polymer concentration for additives such as guar gum and polyethelene oxide. The measurements were also made as a function of dissolved gas concentration, surface tension and viscosity. It was determined that there was a significant increase in the acoustic cavitation threshold for increased concentrations of the polymer additives (measurable effects could be obtained for concentrations as low as a few parts per million). One would normally expect that an additive that reduces surface tension to decrease the pressure required to cause a cavity to grow and thus these additives, at first thought, should reduce the threshold. However, even in the hydrodynamic case, the threshold was increased. In both of the hydrodynamic cases considered, the explanation for the increased threshold was given in terms of changed fluid dynamics rather than changed physical properties of the fluid.

  20. Degradation of carbamazepine using hydrodynamic cavitation combined with advanced oxidation processes.

    PubMed

    Thanekar, Pooja; Panda, Mihir; Gogate, Parag R

    2018-01-01

    Degradation of carbamazepine (CBZ), a widely detected recalcitrant pharmaceutical in sewage treatment plant (STP) effluent, has been studied in the present work using combination of hydrodynamic cavitation (HC) and advanced oxidation processes (AOPs). Due to its recalcitrant nature, it cannot be removed effectively by the conventional wastewater treatment plants (WWTPs) which make CBZ a pharmaceutical of very high environmental relevance and impact as well as stressing the need for developing new treatment schemes. In the present study, the effect of inlet pressure (3-5bar) and operating pH (3-11) on the extent of degradation have been initially studied with an objective of maximizing the degradation using HC alone. The established optimum conditions as pressure of 4bar and pH of 4 resulted in maximum degradation of CBZ as 38.7%. The combined approaches of HC with ultraviolet irradiation (HC+UV), hydrogen peroxide (HC+H 2 O 2 ), ozone (HC+O 3 ) as well as combination of HC, H 2 O 2 and O 3 (HC+H 2 O 2 +O 3 ) have been investigated under optimized pressure and operating pH. It was observed that a significant increase in the extent of degradation is obtained for the combined operations of HC+H 2 O 2 +O 3 , HC+O 3 , HC+H 2 O 2 , and HC+UV with the actual extent of degradation being 100%, 91.4%, 58.3% and 52.9% respectively. Kinetic analysis revealed that degradation of CBZ fitted into first order kinetics model for all the approaches. The processes were also compared on the basis of cavitational yield and also in terms of total treatment cost. Overall, it has been demonstrated that combined process of HC, H 2 O 2 and O 3 can be effectively used for treatment of wastewater containing CBZ. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Closed loop cavitation control - A step towards sonomechatronics.

    PubMed

    Saalbach, Kai-Alexander; Ohrdes, Hendrik; Twiefel, Jens

    2018-06-01

    In the field of sonochemistry, many processes are made possible by the generation of cavitation. This article is about closed loop control of ultrasound assisted processes with the aim of controlling the intensity of cavitation-based sonochemical processes. This is the basis for a new research field which the authors call "sonomechatronics". In order to apply closed loop control, a so called self-sensing technique is applied, which uses the ultrasound transducer's electrical signals to gain information about cavitation activity. Experiments are conducted to find out if this self-sensing technique is capable of determining the state and intensity of acoustic cavitation. A distinct frequency component in the transducer's current signal is found to be a good indicator for the onset and termination of transient cavitation. Measurements show that, depending on the boundary conditions, the onset and termination of transient cavitation occur at different thresholds, with the onset occurring at a higher value in most cases. This known hysteresis effect offers the additional possibility of achieving an energetic optimization by controlling cavitation generation. Using the cavitation indicator for the implementation of a double set point closed loop control, the mean driving current was reduced by approximately 15% compared to the value needed to exceed the transient cavitation threshold. The results presented show a great potential for the field of sonomechatronics. Nevertheless, further investigations are necessary in order to design application-specific sonomechatronic processes. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Cavitation induced Becquerel effect.

    PubMed

    Prevenslik, T V

    2003-06-01

    The observation of an electrical current upon the ultraviolet (UV) illumination of one of a pair of identical electrodes in liquid water, called the Becquerel effect, was made over 150 years ago. More recently, an electrical current was found if the water surrounding one electrode was made to cavitate by focused acoustic radiation, the phenomenon called the cavitation induced Becquerel effect. Since cavitation is known to produce UV light, the electrode may simply absorb the UV light and produce the current by the photo-emission theory of photoelectrochemistry. But the current was found to be semi-logarithmic with the standard electrode potential which is characteristic of the oxidation of the electrode surface in the photo-decomposition theory, and not the photo-emission theory. High bubble collapse temperatures may oxidize the electrode, but this is unlikely because melting was not observed on the electrode surfaces. At ambient temperature, oxidation may proceed by chemical reaction provided a source of vacuum ultraviolet (VUV) radiation is available to produce the excited OH* states of water to react with the electrode. The source of VUV radiation is shown to be the spontaneous emission of coherent infrared (IR) radiation from water molecules in particles that form in bubbles because of surface tension, the spontaneous IR emission induced by cavity quantum electrodynamics. The excited OH* states are produced as the IR radiation accumulates to VUV levels in the bubble wall molecules.

  3. Empirical evaluation of pump inlet compliance

    NASA Technical Reports Server (NTRS)

    Ghahremani, F. G.; Rubin, S.

    1972-01-01

    Cavitation compliance was determined experimentally from pulsing tests on a number of rocket turbopumps. The primary test data used for this study are those for the Rocketdyne H-1, F-1, and J-2 oxidizer and fuel pumps employed on Saturn vehicles. The study shows that these data can be correlated by a particular form of nondimensionalization, the key feature of which is to divide the operating cavitation number or suction specific speed by its value at head breakdown. An expression is obtained for a best-fit curve for these data. Another set of test data for the Aerojet LR87 and 91 pumps can be correlated by a somewhat different nondimensional pump performance parameter, specifically by relating the cavitation number to its position between the head breakdown point and the point of zero slope of the head coefficient versus cavitation number. Recommendations are given for the estimation of the cavitation compliance for new designs in the Rocketdyne family of pumps.

  4. Ultrasonic cavitation erosion-corrosion behavior of friction stir processed stainless steel.

    PubMed

    Selvam, Karthikeyan; Mandal, Priya; Grewal, Harpreet Singh; Arora, Harpreet Singh

    2018-06-01

    Cavitation erosion remains the primary cause of material degradation in fluid machinery components operating at high speed. Micro-jets/shock waves caused by implosion of bubbles on material surface results in significant material loss and premature failure of the components. The presence of corrosive medium further exuberates this effect, causing rapid degradation. Here, we demonstrate a novel pathway to control cavitation erosion-corrosion by tailoring the surface properties using submerged friction stir processing (FSP), a severe plastic deformation process. FSP parameters were varied over wide range of strain-rates to generate tailored microstructures. High strain-rate processing resulted in nearly single phase fine grained structure while low strain-rate processing resulted in phase transformation in addition to grain refinement. As-received and processed samples were subjected to ultrasonic cavitation in distilled water as well as in corrosive environment of 3.5% NaCl solution. Individual roles of cavitation erosion, corrosion and their synergistic effects were analyzed. Depending on the microstructure, processed samples showed nearly 4-6 times higher cavitation erosion resistance compared to as-received alloy. Superior cavitation erosion-corrosion resistance of processed samples was attributed to surface strengthening, higher strain-hardening ability and quick passivation kinetics. The results of current study could be potentially transformative in designing robust materials for hydro-dynamic applications. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. Experimental Waterflow Determination of the Dynamic Hydraulic Transfer Function for the J-2X Oxidizer Turbopump. Part Two; Results and Interpretation

    NASA Technical Reports Server (NTRS)

    Zoladz, Tom; Patel, Sandeep; Lee, Erik; Karon, Dave

    2011-01-01

    Experimental results describing the hydraulic dynamic pump transfer matrix (Yp) for a cavitating J-2X oxidizer turbopump inducer+impeller tested in subscale waterflow are presented. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Dynamic transfer functions across widely varying pump hydrodynamic inlet conditions are extracted from measured data in conjunction with 1D-model based corrections. Derived Dynamic transfer functions are initially interpreted relative to traditional Pogo pump equations. Water-to-liquid oxygen scaling of measured cavitation characteristics are discussed. Comparison of key dynamic transfer matrix terms derived from waterflow testing are made with those implemented in preliminary Ares Upper Stage Pogo stability modeling. Alternate cavitating pump hydraulic dynamic equations are suggested which better reflect frequency dependencies of measured transfer matrices.

  6. Hydrodynamic cavitation as a novel approach for delignification of wheat straw for paper manufacturing.

    PubMed

    Badve, Mandar P; Gogate, Parag R; Pandit, Aniruddha B; Csoka, Levente

    2014-01-01

    The present work deals with application of hydrodynamic cavitation for intensification of delignification of wheat straw as an essential step in the paper manufacturing process. Wheat straw was first treated with potassium hydroxide (KOH) for 48 h and subsequently alkali treated wheat straw was subjected to hydrodynamic cavitation. Hydrodynamic cavitation reactor used in the work is basically a stator and rotor assembly, where the rotor is provided with indentations and cavitational events are expected to occur on the surface of rotor as well as within the indentations. It has been observed that treatment of alkali treated wheat straw in hydrodynamic cavitation reactor for 10-15 min increases the tensile index of the synthesized paper sheets to about 50-55%, which is sufficient for paper board manufacture. The final mechanical properties of the paper can be effectively managed by controlling the processing parameters as well as the cavitational parameters. It has also been established that hydrodynamic cavitation proves to be an effective method over other standard digestion techniques of delignification in terms of electrical energy requirements as well as the required time for processing. Overall, the work is first of its kind application of hydrodynamic cavitation for enhancing the effectiveness of delignification and presents novel results of significant interest to the paper and pulp industry opening an entirely new area of application of cavitational reactors. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. A simple process to achieve microchannels geometries able to produce hydrodynamic cavitation

    NASA Astrophysics Data System (ADS)

    Qiu, X.; Cherief, W.; Colombet, D.; Ayela, F.

    2017-04-01

    We present a simple process to perform microchannels in which cavitating two phase flows are easily producible. Up to now, hydrodynamic cavitation ‘on a chip’ was reached with small flow rates inside microchannels whose micromachining had involved a deep reactive ion etching (D-RIE). The process we present here does not require a D-RIE reactor, as it is only funded on a wet etching of silicon. It leads to a so-called microstep profile, and large cavitating flow rates become possible together with moderate pressure drops.

  8. Drag Reducing and Cavitation Resistant Coatings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pease, Leonard F.

    2016-12-28

    Client, Green Building Systems (GBS), presented PNNL a coating reported to reduce drag and prevent cavitation damage on marine vessels, turbines and pumps. The composition of the coating remains proprietary but has as constituents including silicon oxides, aliphatic carbon chains, and fluorine rich particles. The coating is spray applied to surfaces. Prior GBS testing and experiments suggest reduction of both drag and cavitation on industrial scale propellers, but the underlying mechanism for these effects remains unclear. Yet, the application is compelling because even modest reductions in drag to marine vessels and cavitation to propellers and turbines present a significant economicmore » and environmental opportunity. To discern among possible mechanisms, PNNL considered possible mechanisms with the client, executed multiple experiments, and completed one theoretical analysis (see appendix). The remainder of this report first considers image analysis to gain insight into drag reduction mechanisms and then exposes the coating to cavitation to explore its response to an intensely cavitating environment. Although further efforts may be warranted to confirm mechanisms, this report presents a first investigation into these coatings within the scope and resources of the technology assistance program (TAP).« less

  9. Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling.

    PubMed

    Belcik, J Todd; Davidson, Brian P; Xie, Aris; Wu, Melinda D; Yadava, Mrinal; Qi, Yue; Liang, Sherry; Chon, Chae Ryung; Ammi, Azzdine Y; Field, Joshua; Harmann, Leanne; Chilian, William M; Linden, Joel; Lindner, Jonathan R

    2017-03-28

    Augmentation of tissue blood flow by therapeutic ultrasound is thought to rely on convective shear. Microbubble contrast agents that undergo ultrasound-mediated cavitation markedly amplify these effects. We hypothesized that purinergic signaling is responsible for shear-dependent increases in muscle perfusion during therapeutic cavitation. Unilateral exposure of the proximal hindlimb of mice (with or without ischemia produced by iliac ligation) to therapeutic ultrasound (1.3 MHz, mechanical index 1.3) was performed for 10 minutes after intravenous injection of 2×10 8 lipid microbubbles. Microvascular perfusion was evaluated by low-power contrast ultrasound perfusion imaging. In vivo muscle ATP release and in vitro ATP release from endothelial cells or erythrocytes were assessed by a luciferin-luciferase assay. Purinergic signaling pathways were assessed by studying interventions that (1) accelerated ATP degradation; (2) inhibited P2Y receptors, adenosine receptors, or K ATP channels; or (3) inhibited downstream signaling pathways involving endothelial nitric oxide synthase or prostanoid production (indomethacin). Augmentation in muscle perfusion by ultrasound cavitation was assessed in a proof-of-concept clinical trial in 12 subjects with stable sickle cell disease. Therapeutic ultrasound cavitation increased muscle perfusion by 7-fold in normal mice, reversed tissue ischemia for up to 24 hours in the murine model of peripheral artery disease, and doubled muscle perfusion in patients with sickle cell disease. Augmentation in flow extended well beyond the region of ultrasound exposure. Ultrasound cavitation produced an ≈40-fold focal and sustained increase in ATP, the source of which included both endothelial cells and erythrocytes. Inhibitory studies indicated that ATP was a critical mediator of flow augmentation that acts primarily through either P2Y receptors or adenosine produced by ectonucleotidase activity. Combined indomethacin and inhibition of endothelial nitric oxide synthase abolished the effects of therapeutic ultrasound, indicating downstream signaling through both nitric oxide and prostaglandins. Therapeutic ultrasound using microbubble cavitation to increase muscle perfusion relies on shear-dependent increases in ATP, which can act through a diverse portfolio of purinergic signaling pathways. These events can reverse hindlimb ischemia in mice for >24 hours and increase muscle blood flow in patients with sickle cell disease. URL: http://clinicaltrials.gov. Unique identifier: NCT01566890. © 2017 American Heart Association, Inc.

  10. Study on tip leakage vortex cavitating flows using a visualization method

    NASA Astrophysics Data System (ADS)

    Zhao, Yu; Jiang, Yutong; Cao, Xiaolong; Wang, Guoyu

    2018-01-01

    Experimental investigations of unsteady cavitating flows in a hydrofoil tip leakage region with different gap sizes are conducted to highlight the development of gap cavitation. The experiments were taken in a closed cavitation tunnel, during which high-speed camera had been used to capture the cavitation patterns. A new visualization method based on image processing was developed to capture time-dependent cavitation patterns. The results show that the visualization method can effectively capture the cavitation patterns in the tip region, including both the attached cavity in the gap and the tip leakage vortex (TLV) cavity near the trailing edge. Moreover, with the decrease of cavitation number, the TLV cavity develops from a rapid onset-growth-collapse process to a continuous process, and extends both upstream and downstream. The attached cavity in the gap develops gradually stretching beyond the gap and combines with the vortex cavity to form the triangle cavitating region. Furthermore, the influences of gap size on the cavitation are also discussed. The gap size has a great influence on the loss across the gap, and hence the locations of the inception attached cavity. Besides, inception locations and extending direction of the TLV cavity with different gap sizes also differ. The TLV in the case with τ = 0.061 is more likely to be jet-like compared with that in the case with τ = 0.024, and the gap size has a great influence on the TLV strength.

  11. Cavitation erosion - scale effect and model investigations

    NASA Astrophysics Data System (ADS)

    Geiger, F.; Rutschmann, P.

    2015-12-01

    The experimental works presented in here contribute to the clarification of erosive effects of hydrodynamic cavitation. Comprehensive cavitation erosion test series were conducted for transient cloud cavitation in the shear layer of prismatic bodies. The erosion pattern and erosion rates were determined with a mineral based volume loss technique and with a metal based pit count system competitively. The results clarified the underlying scale effects and revealed a strong non-linear material dependency, which indicated significantly different damage processes for both material types. Furthermore, the size and dynamics of the cavitation clouds have been assessed by optical detection. The fluctuations of the cloud sizes showed a maximum value for those cavitation numbers related to maximum erosive aggressiveness. The finding suggests the suitability of a model approach which relates the erosion process to cavitation cloud dynamics. An enhanced experimental setup is projected to further clarify these issues.

  12. Unraveling the Geometry Dependence of In-Nozzle Cavitation in High-Pressure Injectors

    PubMed Central

    Im, Kyoung-Su; Cheong, Seong-Kyun; Powell, Christopher F.; Lai, Ming-chia D.; Wang, Jin

    2013-01-01

    Cavitation is an intricate multiphase phenomenon that interplays with turbulence in fluid flows. It exhibits clear duality in characteristics, being both destructive and beneficial in our daily lives and industrial processes. Despite the multitude of occurrences of this phenomenon, highly dynamic and multiphase cavitating flows have not been fundamentally well understood in guiding the effort to harness the transient and localized power generated by this process. In a microscale, multiphase flow liquid injection system, we synergistically combined experiments using time-resolved x-radiography and a novel simulation method to reveal the relationship between the injector geometry and the in-nozzle cavitation quantitatively. We demonstrate that a slight alteration of the geometry on the micrometer scale can induce distinct laminar-like or cavitating flows, validating the multiphase computational fluid dynamics simulation. Furthermore, the simulation identifies a critical geometric parameter with which the high-speed flow undergoes an intriguing transition from non-cavitating to cavitating. PMID:23797665

  13. Generation of OH Radical by Ultrasonic Irradiation in Batch and Circulatory Reactor

    NASA Astrophysics Data System (ADS)

    Fang, Yu; Shimizu, Sayaka; Yamamoto, Takuya; Komarov, Sergey

    2018-03-01

    Ultrasonic technology has been widely investigated in the past as one of the advance oxidation processes to treat wastewater, in this process acoustic cavitation causes generation of OH radical, which play a vital role in improving the treatment efficiency. In this study, OH radical formation rate was measured in batch and circulatory reactor by using Weissler reaction at various ultrasound output power. It is found that the generation rate in batch reactor is higher than that in circulatory reactor at the same output power. The generation rate tended to be slower when output power exceeds 137W. The optimum condition for circulatory reactor was found to be 137W output and 4L/min flow rate. Results of aluminum foil erosion test revealed a strong dependence of cavitation zone length on the ultrasound output power. This is assumed to be one of the reasons why the generation rate of HO radicals becomes slower at higher output power in circulatory reactor.

  14. A review and assessment of hydrodynamic cavitation as a technology for the future.

    PubMed

    Gogate, Parag R; Pandit, Aniruddha B

    2005-01-01

    In the present work, the current status of the hydrodynamic cavitation reactors has been reviewed discussing the bubble dynamics analysis, optimum design considerations, design correlations for cavitational intensity (in terms of collapse pressure)/cavitational yield and different successful chemical synthesis applications clearly illustrating the utility of these types of reactors. The theoretical discussion based on the modeling of the bubble dynamics equations aims at understanding the design information related to the dependency of the cavitational intensity on the operating parameters and recommendations have been made for the choice of the optimized conditions of operating parameters. The design information based on the theoretical analysis has also been supported with some experimental illustrations concentrating on the chemical synthesis applications. Assessment of the hydrodynamic cavitation reactors and comparison with the sonochemical reactors has been done by citing the different industrially important reactions (oxidation of toluene, o-xylene, m-xylene, p-xylene, mesitylene, o-nitrotoluene, p-nitrotoluene, m-nitrotoluene, o-chlorotoluene and p-chlorotoulene, and trans-esterification reaction i.e., synthesis of bio-diesel). Some recommendations have also been made for the future work to be carried out as well as the choice of the operating conditions for realizing the dream of industrial scale applications of the cavitational reactors.

  15. Current research in cavitating fluid films

    NASA Technical Reports Server (NTRS)

    Brewe, D. E. (Editor); Ball, J. H. (Editor); Khonsari, M. M. (Editor)

    1990-01-01

    A review of the current research of cavitation in fluid films is presented. Phenomena and experimental observations include gaseous cavitation, vapor cavitation, and gas entrainment. Cavitation in flooded, starved, and dynamically loaded journal bearings, as well as squeeze films are reviewed. Observations of cavitation damage in bearings and the possibility of cavitation between parallel plates with microasperities were discussed. The transcavity fluid transport process, meniscus motion and geometry or form of the film during rupture, and reformation were summarized. Performance effects were related to heat transfer models in the cavitated region and hysteresis influence on rotor dynamics coefficients. A number of cavitation algorithms was presented together with solution procedures using the finite difference and finite element methods. Although Newtonian fluids were assumed in most of the discussions, the effect of non-Newtonian fluids on cavitation was also discussed.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Disselkamp, Robert S.; Chajkowski, Sarah M.; Boyles, Kelly R.

    Here we discuss results obtained as part of a three-year investigation at Pacific Northwest National Laboratory of ultrasound processing to effect selectivity and activity in the hydrogenation of water-soluble olefins on transition metal catalysts. We have shown previously that of the two regimes for ultrasound processing, high-power cavitating and high-power non-cavitating, only the former can effect product selectivity dramatically (> 1000%) whereas the selectivity of the latter was comparable with those obtained in stirred/silent control experiments [R.S. Disselkamp, Y.-H. Chin, C.H.F. Peden, J. Catal., 227, 552 (2005)]. As a means of ensuring the benefits of cavitating ultrasound processing, we introducedmore » the concept of employing inert dopants into the reacting solution. These inert dopants do not partake in solution chemistry but enable a more facile transition from high-power non-cavitating to cavitating conditions during sonication treatment. With cavitation processing conditions ensured, we discuss here results of isotopic H/D substitution for a variety of substrates and illustrate how such isotope dependent chemistries during substrate hydrogenation elucidate detailed mechanistic information about these reaction systems.« less

  17. Numerical simulation of cryogenic cavitating flow by an extended transport-based cavitation model with thermal effects

    NASA Astrophysics Data System (ADS)

    Zhang, Shaofeng; Li, Xiaojun; Zhu, Zuchao

    2018-06-01

    Thermodynamic effects on cryogenic cavitating flow is important to the accuracy of numerical simulations mainly because cryogenic fluids are thermo-sensitive, and the vapour saturation pressure is strongly dependent on the local temperature. The present study analyses the thermal cavitating flows in liquid nitrogen around a 2D hydrofoil. Thermal effects were considered using the RNG k-ε turbulence model with a modified turbulent eddy viscosity and the mass transfer homogenous cavitation model coupled with energy equation. In the cavitation model process, the saturated vapour pressure is modified based on the Clausius-Clapron equation. The convection heat transfer approach is also considered to extend the Zwart-Gerber-Belamri model. The predicted pressure and temperature inside the cavity under cryogenic conditions show that the modified Zwart-Gerber-Belamri model is in agreement with the experimental data of Hord et al. in NASA, especially in the thermal field. The thermal effect significantly affects the cavitation dynamics during phase-change process, which could delay or suppress the occurrence and development of cavitation behaviour. Based on the modified Zwart-Gerber-Belamri model proposed in this paper, better prediction of the cryogenic cavitation is attainable.

  18. The role of ultrasonic cavitation in refining the microstructure of aluminum based nanocomposites during the solidification process.

    PubMed

    Xuan, Yang; Nastac, Laurentiu

    2018-02-01

    Recent studies showed that the microstructure and mechanical properties of aluminum based nanocomposites can be significantly improved when ultrasonic cavitation and solidification processing is used. This is because ultrasonic cavitation processing plays an important role not only in degassing and dispersion of the nanoparticles, but also in breaking up the dendritic grains and refining the as-cast microstructure. In the present study, A356 alloy and Al 2 O 3 nanoparticles are used as the matrix alloy and the reinforcement, respectively. Nanoparticles were added into the molten A356 alloy and dispersed via ultrasonic cavitation processing. Ultrasonic cavitation was applied over various temperature ranges during molten alloy cooling and solidification to investigate the grain structure formation and the nanoparticle dispersion behavior. Optical Microscopy and Scanning Electron Microscopy were used to investigate in detail the differences in the microstructure characteristics and the nanoparticle distribution. Experimental results indicated that the ultrasonic cavitation processing and Al 2 O 3 nanoparticles play an important role for microstructure refinement. In addition, it was shown in this study that the Al 2 O 3 nanoparticles modified the eutectic phase. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Application of the "Full Cavitation Model" to the fundamental study of cavitation in liquid metal processing

    NASA Astrophysics Data System (ADS)

    Lebon, G. S. B.; Pericleous, K.; Tzanakis, I.; Eskin, D.

    2015-01-01

    Ultrasonic cavitation treatment of melt significantly improves the downstream properties and quality of conventional and advanced metallic materials. However, the transfer of this technology has been hindered by difficulties in treating large volumes of liquid metal. To improve the understanding of cavitation processing efficiency, the Full Cavitation Model, which is derived from a reduced form of the Rayleigh-Plesset equation, is modified and applied to the two-phase problem of bubble propagation in liquid melt. Numerical simulations of the sound propagation are performed in the microsecond time scale to predict the maximum and minimum acoustic pressure amplitude fields in the domain. This field is applied to the source term of the bubble transport equation to predict the generation and destruction of cavitation bubbles in a time scale relevant to the fluid flow. The use of baffles to limit flow speed in a launder conduit is studied numerically, to determine the optimum configuration that maximizes the residence time of the liquid in high cavitation activity regions. With this configuration, it is then possible to convert the batch processing of liquid metal into a continuous process. The numerical simulations will be validated against water and aluminium alloy experiments, carried out at Brunel University.

  20. Phase-shift nano-emulsions induced cavitation and ablation during high intensity focused ultrasound exposure

    NASA Astrophysics Data System (ADS)

    Qiao, Yangzi; Yin, Hui; Chang, Nan; Wan, Mingxi

    2017-03-01

    Phase-shift Nano-emulsions (PSNEs) with a small initial diameter in nanoscale have the potential to leak out of the blood vessels and to accumulate at target point of tissue. At desired location, PSNEs can undergo acoustic droplet vaporization (ADV) process, change into gas bubbles and enhance focused ultrasound efficiency. The aim of this work was to provide spatial and temporal information on PSNE induced cavitation and ablation effects during pulsed high intensity focused ultrasound (HIFU) exposure. The PSNEs were composed of perfluorohaxane (PFH) and bovine serum albumin (BSA), and then uniformly distributed in a transparent polyacrylamide phantom. The Sonoluminescence (SL) method was employed to visualize the cavitation distribution and formation process of PSNEs induced cavitation. For the phantom which was used for ablation observation, heat sensitive BSA was added. When the temperature generated by ultrasound exposure was high enough to denature BSA, the transparent phantom would turn out white lesions. The shape of the lesion and the formation process were compared with those of cavitation. Each of the pulse contained 12 cycles for a duration of 10 µs. And the duty cycle changed from 1:10 to 1:40. The total "on" time of HIFU was 2s. PSNE can evidently accelerate cavitation emitting bright SL in pre-focal region. The cavitation was generated layer by layer towards the transducer. The formed bubble wall can block acoustic waves transmitting to the distal end. And the lesion appeared to be separated into two parts. One in pre-focal region stemmed from one point and grew quickly toward the transducer. The other in focal region was formed by merging some small white dots, and grew much slower. The influence of duty cycle has also been examined. The lower duty cycle with longer pulse-off time would generate more intense cavitation, however, smaller lesion. Bubble cloud gradually developed within phantom would greatly influence the cavitation and ablation process. One hand, the evaporated bubbles could enhance both the cavitation and thermal effects of HIFU. The other hand, outside layer bubbles would block the acoustic wave transmission, inducing distinctive cavitation and ablation formation process. The spatial distribution of cavitation and lesion organized into special structures under different acoustic parameters.

  1. Investigations in physical mechanism of the oxidative desulfurization process assisted simultaneously by phase transfer agent and ultrasound.

    PubMed

    Bhasarkar, Jaykumar B; Chakma, Sankar; Moholkar, Vijayanand S

    2015-05-01

    This paper attempts to discern the physical mechanism of the oxidative desulfurization process simultaneously assisted by ultrasound and phase transfer agent (PTA). With different experimental protocols, an attempt is made to deduce individual beneficial effects of PTA and ultrasound on the oxidative desulfurization system, and also the synergy between the effects of PTA and ultrasound. Effect of PTA is more marked for mechanically stirred system due to mass transfer limitations, while intense emulsification due to ultrasound helps overcome the mass transfer limitations and reduces the extent of enhancement of oxidation by PTA. Despite application of PTA and ultrasound, the intrinsic factors and properties of the reactants such as polarity (and hence partition coefficient) and diffusivity have a crucial effect on the extent of oxidation. The intrinsic reactivity of the oxidant also plays a vital role, as seen from the extent of oxidation achieved with performic acid and peracetic acid. The interfacial transport of oxidant in the form of oxidant-PTA complex reduces the undesired consumption of oxidant by the reducing species formed during transient cavitation in organic medium, which helps effective utilization of oxidant towards desulfurization. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Cavitating Jet Method and System for Oxygenation of Liquids

    NASA Technical Reports Server (NTRS)

    Chahine, Georges L.

    2012-01-01

    Reclamation and re-use of water is critical for space-based life support systems. A number of functions must be performed by any such system including removal of various contaminants and oxygenation. For long-duration space missions, this must be done with a compact, reliable system that requires little or no use of expendables and minimal power. DynaJets cavitating jets can oxidize selected organic compounds with much greater energy efficiency than ultrasonic devices typically used in sonochemistry. The focus of this work was to develop cavitating jets to simultaneously accomplish the functions of oxygenation and removal of contaminants of importance to space-structured water reclamation systems. The innovation is a method to increase the concentration of dissolved oxygen or other gasses in a liquid. It utilizes a particular form of novel cavitating jet operating at low to moderate pressures to achieve a high-efficiency means of transporting and mixing the gas into the liquid. When such a jet is utilized to simultaneously oxygenate the liquid and to oxidize organic compounds within the liquid, such as those in waste water, the rates of contaminant removal are increased. The invention is directed toward an increase in the dissolved gas content of a liquid, in general, and the dissolved oxygen content of a liquid in particular.

  3. Statistical characteristics of mechanical heart valve cavitation in accelerated testing.

    PubMed

    Wu, Changfu; Hwang, Ned H C; Lin, Yu-Kweng M

    2004-07-01

    Cavitation damage has been observed on mechanical heart valves (MHVs) undergoing accelerated testing. Cavitation itself can be modeled as a stochastic process, as it varies from beat to beat of the testing machine. This in-vitro study was undertaken to investigate the statistical characteristics of MHV cavitation. A 25-mm St. Jude Medical bileaflet MHV (SJM 25) was tested in an accelerated tester at various pulse rates, ranging from 300 to 1,000 bpm, with stepwise increments of 100 bpm. A miniature pressure transducer was placed near a leaflet tip on the inflow side of the valve, to monitor regional transient pressure fluctuations at instants of valve closure. The pressure trace associated with each beat was passed through a 70 kHz high-pass digital filter to extract the high-frequency oscillation (HFO) components resulting from the collapse of cavitation bubbles. Three intensity-related measures were calculated for each HFO burst: its time span; its local root-mean-square (LRMS) value; and the area enveloped by the absolute value of the HFO pressure trace and the time axis, referred to as cavitation impulse. These were treated as stochastic processes, of which the first-order probability density functions (PDFs) were estimated for each test rate. Both the LRMS value and cavitation impulse were log-normal distributed, and the time span was normal distributed. These distribution laws were consistent at different test rates. The present investigation was directed at understanding MHV cavitation as a stochastic process. The results provide a basis for establishing further the statistical relationship between cavitation intensity and time-evolving cavitation damage on MHV surfaces. These data are required to assess and compare the performance of MHVs of different designs.

  4. Effect of Spray Particle Velocity on Cavitation Erosion Resistance Characteristics of HVOF and HVAF Processed 86WC-10Co4Cr Hydro Turbine Coatings

    NASA Astrophysics Data System (ADS)

    Kumar, R. K.; Kamaraj, M.; Seetharamu, S.; Pramod, T.; Sampathkumaran, P.

    2016-08-01

    The hydro plants utilizing silt-laden water for power generation suffer from severe metal wastage due to particle-induced erosion and cavitation. High-velocity oxy-fuel process (HVOF)-based coatings is widely applied to improve the erosion life. The process parameters such as particle velocity, size, powder feed rate, temperature, affect their mechanical properties. The high-velocity air fuel (HVAF) technology, with higher particle velocities and lower spray temperatures, gives dense and substantially nonoxidized coating. In the present study, the cavitation resistance of 86WC-10Co4Cr-type HVOF coating processed at 680 m/s spray particle velocity was compared with HVAF coatings made at 895, 960, and 1010 m/s. The properties such as porosity, hardness, indentation toughness, and cavitation resistance were investigated. The surface damage morphology has been analyzed in SEM. The cohesion between different layers has been examined qualitatively through scratch depth measurements across the cross section. The HVAF coatings have shown a lower porosity, higher hardness, and superior cavitation resistance. Delamination, extensive cracking of the matrix interface, and detachment of the WC grains were observed in HVOF coating. The rate of metal loss is low in HVAF coatings implying that process parameters play a vital role in achieving improved cavitation resistance.

  5. J-2X Turbopump Cavitation Diagnostics

    NASA Technical Reports Server (NTRS)

    Santi, I. Michael; Butas, John P.; Tyler, Thomas R., Jr.; Aguilar, Robert; Sowers, T. Shane

    2010-01-01

    The J-2X is the upper stage engine currently being designed by Pratt & Whitney Rocketdyne (PWR) for the Ares I Crew Launch Vehicle (CLV). Propellant supply requirements for the J-2X are defined by the Ares Upper Stage to J-2X Interface Control Document (ICD). Supply conditions outside ICD defined start or run boxes can induce turbopump cavitation leading to interruption of J-2X propellant flow during hot fire operation. In severe cases, cavitation can lead to uncontained engine failure with the potential to cause a vehicle catastrophic event. Turbopump and engine system performance models supported by system design information and test data are required to predict existence, severity, and consequences of a cavitation event. A cavitation model for each of the J-2X fuel and oxidizer turbopumps was developed using data from pump water flow test facilities at Pratt & Whitney Rocketdyne (PWR) and Marshall Space Flight Center (MSFC) together with data from Powerpack 1A testing at Stennis Space Center (SSC) and from heritage systems. These component models were implemented within the PWR J-2X Real Time Model (RTM) to provide a foundation for predicting system level effects following turbopump cavitation. The RTM serves as a general failure simulation platform supporting estimation of J-2X redline system effectiveness. A study to compare cavitation induced conditions with component level structural limit thresholds throughout the engine was performed using the RTM. Results provided insight into system level turbopump cavitation effects and redline system effectiveness in preventing structural limit violations. A need to better understand structural limits and redline system failure mitigation potential in the event of fuel side cavitation was indicated. This paper examines study results, efforts to mature J-2X turbopump cavitation models and structural limits, and issues with engine redline detection of cavitation and the use of vehicle-side abort triggers to augment the engine redline system.

  6. A sonochemical approach to the direct surface functionalization of superparamagnetic iron oxide nanoparticles with (3-aminopropyl)triethoxysilane.

    PubMed

    Sodipo, Bashiru Kayode; Aziz, Azlan Abdul

    2014-01-01

    We report a sonochemical method of functionalizing superparamagnetic iron oxide nanoparticles (SPION) with (3-aminopropyl)triethoxysilane (APTES). Mechanical stirring, localized hot spots and other unique conditions generated by an acoustic cavitation (sonochemical) process were found to induce a rapid silanization reaction between SPION and APTES. FTIR, XPS and XRD measurements were used to demonstrate the grafting of APTES on SPION. Compared to what was reported in literature, the results showed that the silanization reaction time was greatly minimized. More importantly, the product displayed superparamagnetic behaviour at room temperature with a more than 20% higher saturation magnetization.

  7. Numerical and experimental investigations on cavitation erosion

    NASA Astrophysics Data System (ADS)

    Fortes Patella, R.; Archer, A.; Flageul, C.

    2012-11-01

    A method is proposed to predict cavitation damage from cavitating flow simulations. For this purpose, a numerical process coupling cavitating flow simulations and erosion models was developed and applied to a two-dimensional (2D) hydrofoil tested at TUD (Darmstadt University of Technology, Germany) [1] and to a NACA 65012 tested at LMH-EPFL (Lausanne Polytechnic School) [2]. Cavitation erosion tests (pitting tests) were carried out and a 3D laser profilometry was used to analyze surfaces damaged by cavitation [3]. The method allows evaluating the pit characteristics, and mainly the volume damage rates. The paper describes the developed erosion model, the technique of cavitation damage measurement and presents some comparisons between experimental results and numerical damage predictions. The extent of cavitation erosion was correctly estimated in both hydrofoil geometries. The simulated qualitative influence of flow velocity, sigma value and gas content on cavitation damage agreed well with experimental observations.

  8. Detecting cavitation in vivo from shock-wave therapy devices

    NASA Astrophysics Data System (ADS)

    Matula, Thomas J.; Yu, Jinfei; Bailey, Michael R.

    2005-04-01

    Extracorporeal shock-wave therapy (ESWT) has been used as a treatment for plantar faciitis, lateral epicondylitis, shoulder tendonitis, non-unions, and other indications where conservative treatments have been unsuccessful. However, in many areas, the efficacy of SW treatment has not been well established, and the mechanism of action, particularly the role of cavitation, is not well understood. Research indicates cavitation plays an important role in other ultrasound therapies, such as lithotripsy and focused ultrasound surgery, and in some instances, cavitation has been used as a means to monitor or detect a biological effect. Although ESWT can generate cavitation easily in vitro, it is unknown whether or not cavitation is a significant factor in vivo. The purpose of this investigation is to use diagnostic ultrasound to detect and monitor cavitation generated by ESWT devices in vivo. Diagnostic images are collected at various times during and after treatment. The images are then post-processed with image-processing algorithms to enhance the contrast between bubbles and surrounding tissue. The ultimate goal of this research is to utilize cavitation as a means for optimizing shock wave parameters such as amplitude and pulse repetition frequency. [Work supported by APL internal funds and NIH DK43881 and DK55674.

  9. Synthesis of nanometer-size inorganic materials for the examination of particle size effects on heterogeneous catalysis

    NASA Astrophysics Data System (ADS)

    Emerson, Sean Christian

    The effect of acoustic and hydrodynamic cavitation on the precipitation of inorganic catalytic materials, specifically titania supported gold, was investigated. The overall objective was to understand the fundamental factors involved in synthesizing nanometer-size catalytic materials in the 1--10 nm range in a cavitating field. Materials with grain sizes in this range have been associated with enhanced catalytic activity compared to larger grain size materials. A new chemical approach was used to produce titania supported gold by co-precipitation with higher gold yields compared to other synthesis methods. Using this approach, it was determined that acoustic cavitation was unable to influence the gold mean crystallite size compared to non-sonicated catalysts. However, gold concentration on the catalysts was found to be very important for CO oxidation activity. By decreasing the gold concentration from a weight loading of 0.50% down to approximately 0.05%, the rate of reaction per mole of gold was found to increase by a factor of 19. Hydrodynamic cavitation at low pressures (6.9--48 bar) was determined to have no effect on gold crystallite size at a fixed gold content for the same precipitation technique used in the acoustic cavitation studies. By changing the chemistry of the precipitation system, however, it was found that a synergy existed between the dilution of the gold precursor solution, the orifice diameter, and the reducing agent addition rate. Individually, these factors were found to have little effect and only their interaction allowed gold grain size control in the range of 8--80 nm. Further modification of the system chemistry and the use of hydrodynamic cavitation at pressures in excess of 690 bar allowed the systematic control of gold crystallite size in the range of 2--9 nm for catalysts containing 2.27 +/- 0.17% gold. In addition, it was shown that the enhanced mixing due to cavitation led to larger gold yields compared to classical syntheses. The control of gold grain size was gained at the loss of CO activity, which was attributed to the formation of non-removable sodium titanate species. The increased mixing associated with cavitation contributed to the activity loss by partially burying the gold and incorporating more of the sodium titanate species into the catalysts. This work produced the first evidence of hydrodynamic cavitation influencing the gold crystallite size on titania supported gold catalysts and is the only study reporting the control of grain size by simple mechanical adjustment of the experimental parameters. Despite the low activity observed due to sodium titanate, the methodology of adjusting the chemistry of a precipitating system could be used to eliminate such species. The approach of modifying the chemical precipitation kinetics relative to the dynamics of cavitation offers a general scheme for future research on cavitational processing effects.

  10. Intensification of oxidation capacity using chloroalkanes as additives in hydrodynamic and acoustic cavitation reactors.

    PubMed

    Chakinala, Anand G; Gogate, Parag R; Chand, Rashmi; Bremner, David H; Molina, Raúl; Burgess, Arthur E

    2008-03-01

    The effect of the presence and absence of the chloroalkanes, dichloromethane (CH(2)Cl(2)), chloroform (CHCl(3)) and carbon tetrachloride (CCl(4)) on the extent of oxidation of aqueous I(-) to I(3)(-) has been investigated in (a) a liquid whistle reactor (LWR) generating hydrodynamic cavitation and (b) an ultrasonic probe, which produces acoustic cavitation. The aim has been to examine the intensification achieved in the extent of oxidation due to the generation of additional free radicals/oxidants in the reactor as a result of the presence of chloroalkanes. It has been observed that the extent of increase in the oxidation reaction is strongly dependent on the applied pressure in the case of the LWR. Also, higher volumes of the chloroalkanes favour the intensification and the order of effectiveness is CCl(4)>CHCl(3)>CH(2)Cl(2). However, the results with the ultrasonic probe suggest that an optimum concentration of CH(2)Cl(2) or CHCl(3) exists beyond which there is little increase in the extent of observed intensification. For CCl(4), however, no such optimum concentration was observed and the extent of increase in the rates of oxidation reaction rose with the amount of CCl(4) added. Stage wise addition of the chloroalkanes was found to give marginally better results in the case of the ultrasonic probe as compared to bulk addition at the start of the run. Although CCl(4) is the most effective, its toxicity and carcinogenicity may mean that CH(2)Cl(2) and CHCl(3) offer a safer viable alternative and the present work should be useful in establishing the amount of chloroalkanes required for obtaining a suitable degree of intensification.

  11. Effects of Laser Shock Processing on Morphologies and Mechanical Properties of ANSI 304 Stainless Steel Weldments Subjected to Cavitation Erosion

    PubMed Central

    Zhang, Lei; Lu, Jin-Zhong; Zhang, Yong-Kang; Ma, Hai-Le; Luo, Kai-Yu; Dai, Feng-Ze

    2017-01-01

    Effects of laser shock processing (LSP) on the cavitation erosion resistance of laser weldments were investigated by optical microscope (OM), scanning electron microscope (SEM) observations, roughness tester, micro hardness tester, and X-ray diffraction (XRD) technology. The morphological microstructures were characterized. Cumulative mass loss, incubation period, erosion rate, and damaged surface areas were monitored during cavitation erosion. Surface roughness, micro-hardness, and residual stress were measured in different zones. Results showed that LSP could improve the damage of morphological microstructures and mechanical properties after cavitation erosion. The compressive residual stresses were generated during the process of LSP, which was an effective guarantee for the improvement of the above mentioned properties. PMID:28772652

  12. Hybrid treatment strategies for 2,4,6-trichlorophenol degradation based on combination of hydrodynamic cavitation and AOPs.

    PubMed

    Barik, Arati J; Gogate, Parag R

    2018-01-01

    Utilization of hybrid treatment schemes involving advanced oxidation processes and hydrodynamic cavitation in the wastewater treatment forms the prime focus of the present work. The initial phase of the work includes analysis of recent literature relating to the performance of combined approach based on hydrodynamic cavitation (HC) for degradation of different pollutants followed by a detailed investigation into degradation of 2,4,6-trichlorophenol (2,4,6-TCP). The degradation of the priority pollutant, 2,4,6-TCP, using combination of HC based on slit-venturi used as the cavitating device, ozone and H 2 O 2 has been investigated. The effect of operating pressure (2-5bar) and initial pH (3-11) have been investigated for the degradation using only HC. The degradation using only ozone (100-400mg/h) and only H 2 O 2 has also been studied. The efficacy of the combined operation of HC+O 3 at different ozone flow rates (100-400mg/h) and the combined operation of HC+H 2 O 2 at different loadings of H 2 O 2 (2,4,6-TCP:H 2 O 2 as 1:1-1:7) have been subsequently investigated. The degradation efficacy has also been established for the combined treatment strategies of O 3 +H 2 O 2 and HC+O 3 +H 2 O 2 at the optimum conditions of temperature as 30°C, inlet pressure of 4bar and initial pH of 7. Extent of 2,4,6-TCP degradation, TOC and COD removal obtained for HC+O 3 process were 97.1%, 94.4% and 78.5% respectively whereas for O 3 +H 2 O 2 process, the values were 95.5%, 94.8% and 76.2% and for HC+O 3 +H 2 O 2 process the extent of reduction were 100%, 95.6% and 80.9% in the same order. The combined treatment approach as HC+O 3 +H 2 O 2 was established as the most efficient approach for complete removal of 2,4,6-TCP with near complete TOC removal. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Effect of process intensifying parameters on the hydrodynamic cavitation based degradation of commercial pesticide (methomyl) in the aqueous solution.

    PubMed

    Raut-Jadhav, Sunita; Saini, Daulat; Sonawane, Shirish; Pandit, Aniruddha

    2016-01-01

    Methomyl, a carbamate pesticide, is classified as a pesticide of category-1 toxicity and hence shows harmful effects on both human and aquatic life. In the present work, the degradation of methomyl has been studied by using hydrodynamic cavitation reactor (HC) and its combination with intensifying agents such as H2O2, fenton reagent and ozone (hybrid processes). Initially, the optimization of operating parameters such pH and inlet pressure to the cavitating device (circular venturi) has been carried out for maximizing the efficacy of hydrodynamic cavitation. Further degradation study of methomyl by the application of hybrid processes was carried out at an optimal pH of 2.5 and the optimal inlet pressure of 5 bar. Significant synergetic effect has been observed in case of all the hybrid processes studied. Synergetic coefficient of 5.8, 13.41 and 47.6 has been obtained by combining hydrodynamic cavitation with H2O2, fenton process and ozone respectively. Efficacy of individual and hybrid processes has also been obtained in terms of energy efficiency and extent of mineralization. HC+Ozone process has proved to be the most effective process having highest synergetic coefficient, energy efficiency and the extent of mineralization. The study has also encompassed the identification of intermediate by-products generated during the degradation and has proposed the probable degradation pathway. It has been conclusively established that hydrodynamic cavitation in the presence of intensifying agents can effectively be used for complete degradation of methomyl. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Four-photon spectroscopy of rotational transitions in liquid: recording of changes in the chemical composition of water caused by cavitation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bunkin, Aleksei F; Pershin, S M

    2010-05-26

    It is shown for the first time by the method of four-photon coherent scattering by rotational molecular resonances that the cavitation action on water changes its chemical composition, resulting in the formation of hydrogen peroxide. It is found that the concentration of hydrogen peroxide during cavitation grows by several times and depends on the cavitation process technology.

  15. Cavitation in centrifugal pump with rotating walls of axial inlet device

    NASA Astrophysics Data System (ADS)

    Moloshnyi, O.; Sotnyk, M.

    2017-08-01

    The article deals with the analysis of cavitation processes in the flowing part of the double entry centrifugal pump. The analysis is conducted using numerical modeling of the centrifugal pump operating process in the software environment ANSYS CFX. Two models of the axial inlet device is researched. It is shaped by a cylindrical section and diffuser section in front of the impeller, which includes fairing. The walls of the axial inlet device rotate with the same speed as the pump rotor. The numerical experiment is conducted under the condition of the flow rate change and absolute pressure at the inlet. The analysis shows that the pump has the average statistical cavitation performance. The occurrence of the cavitation in the axial inlet device is after narrowing the cross-section of flow channel and at the beginning of the diffuser section. Additional sudden expansion at the outlet of the axial inlet diffuser section does not affect the cavitation characteristics of the impeller, however, improves cavitation characteristics of the axial inlet device. For considered geometric parameters of the axial inlet device the cavitation in the impeller begins earlier than in the axial inlet device. That is, the considered design of the axial inlet device will not be subjected to destruction at the ensuring operation without cavitation in the impeller.

  16. Investigation of Microbubble Cavitation-Induced Calcein Release from Cells In Vitro.

    PubMed

    Maciulevičius, Martynas; Tamošiūnas, Mindaugas; Jakštys, Baltramiejus; Jurkonis, Rytis; Venslauskas, Mindaugas Saulius; Šatkauskas, Saulius

    2016-12-01

    In the present study, microbubble (MB) cavitation signal analysis was performed together with calcein release evaluation in both pressure and exposure duration domains of the acoustic field. A passive cavitation detection system was used to simultaneously measure MB scattering and attenuation signals for subsequent extraction efficiency relative to MB cavitation activity. The results indicate that the decrease in the efficiency of extraction of calcein molecules from Chinese hamster ovary cells, as well as cell viability, is associated with MB cavitation activity and can be accurately predicted using inertial cavitation doses up to 0.18 V × s (R 2  > 0.9, p < 0.0001). No decrease in additional calcein release or cell viability was observed after complete MB sonodestruction was achieved. This indicates that the optimal exposure duration within which maximal sono-extraction efficiency is obtained coincides with the time necessary to achieve complete MB destruction. These results illustrate the importance of MB inertial cavitation in the sono-extraction process. To our knowledge, this study is the first to (i) investigate small molecule extraction from cells via sonoporation and (ii) relate the extraction process to the quantitative characteristics of MB cavitation acoustic spectra. Copyright © 2016 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  17. Disruption of Brewers' yeast by hydrodynamic cavitation: Process variables and their influence on selective release.

    PubMed

    Balasundaram, B; Harrison, S T L

    2006-06-05

    Intracellular products, not secreted from the microbial cell, are released by breaking the cell envelope consisting of cytoplasmic membrane and an outer cell wall. Hydrodynamic cavitation has been reported to cause microbial cell disruption. By manipulating the operating variables involved, a wide range of intensity of cavitation can be achieved resulting in a varying extent of disruption. The effect of the process variables including cavitation number, initial cell concentration of the suspension and the number of passes across the cavitation zone on the release of enzymes from various locations of the Brewers' yeast was studied. The release profile of the enzymes studied include alpha-glucosidase (periplasmic), invertase (cell wall bound), alcohol dehydrogenase (ADH; cytoplasmic) and glucose-6-phosphate dehydrogenase (G6PDH; cytoplasmic). An optimum cavitation number Cv of 0.13 for maximum disruption was observed across the range Cv 0.09-0.99. The optimum cell concentration was found to be 0.5% (w/v, wet wt) when varying over the range 0.1%-5%. The sustained effect of cavitation on the yeast cell wall when re-circulating the suspension across the cavitation zone was found to release the cell wall bound enzyme invertase (86%) to a greater extent than the enzymes from other locations of the cell (e.g. periplasmic alpha-glucosidase at 17%). Localised damage to the cell wall could be observed using transmission electron microscopy (TEM) of cells subjected to less intense cavitation conditions. Absence of the release of cytoplasmic enzymes to a significant extent, absence of micronisation as observed by TEM and presence of a lower number of proteins bands in the culture supernatant on SDS-PAGE analysis following hydrodynamic cavitation compared to disruption by high-pressure homogenisation confirmed the selective release offered by hydrodynamic cavitation. Copyright 2006 Wiley Periodicals, Inc.

  18. Cavitations synthesis of carbon nanostructures

    NASA Astrophysics Data System (ADS)

    Voropaev, S.

    2011-04-01

    Originally an idea of diamonds production by hydrodynamical cavitation was presented by academician E M Galimov. He supposed the possibility of nature diamonds formation at fast magma flowing in kimberlitic pipes during bubbles collapse. This hypothesis assumes a number of processes, which were not under consideration until now. It concerns cavitation under high pressure, growth and stability of the gas- and vapors bubbles, their evolution, and corresponding physical- and chemical processes inside. Experimental setup to reproduce the high pressure and temperature reaction centers by means of the cavitation following the above idea was created. A few crystalline nanocarbon forms were successfully recovered after treatment of benzene (C6H6).

  19. Cavitation in Poly(4-methyl-1-pentene) during Tensile Deformation.

    PubMed

    Chen, Ran; Lu, Ying; Jiang, Zhiyong; Men, Yongfeng

    2018-04-12

    The poly(4-methyl-1-pentene) sample was used to investigate the cavitation-induced stress-whitening phenomenon during stretching at different temperatures via the ultrasmall-angle X-ray scattering technique. Two modes of cavitation were found that mode I cavitation activated around yield point followed by mode II cavitation generated in highly oriented state. The critical strain for initiating the mode II cavitation increases with the increase of the stretching temperature, whereas the critical stress grew steadily in the lower temperature regime (30-60 °C) and reached a plateau at 70 °C. The appearance of mode II cavitation at large strains was independent of the mode I cavitation. The mode I cavitation was attributed to the competitive process between the formation of cavities and shearing yield of lamellae, whereas the mode II cavitation was proven to be related to the failure of the whole highly oriented entangled amorphous network because of the breaking of interfibrillar load-bearing tie molecules. Size distribution of cavities has been successfully calculated using a model fitting procedure. The results showed that the quantity of cavities increased heavily while the size was kept nearly constant during the propagation of the mode II cavitation.

  20. Intensification of esterification of acids for synthesis of biodiesel using acoustic and hydrodynamic cavitation.

    PubMed

    Kelkar, Mandar A; Gogate, Parag R; Pandit, Aniruddha B

    2008-03-01

    Cavitation results in conditions of turbulence and liquid circulation in the reactor which can aid in eliminating mass transfer resistances. The present work illustrates the use of cavitation for intensification of biodiesel synthesis (esterification) reaction, which is mass transfer limited reaction considering the immiscible nature of the reactants, i.e., fatty acids and alcohol. Esterification of fatty acid (FA) odour cut (C(8)-C(10)) with methanol in the presence of concentrated H(2)SO(4) as a catalyst has been studied in hydrodynamic cavitation reactor as well as in the sonochemical reactor. The different reaction operating parameters such as molar ratio of acid to alcohol, catalyst quantity have been optimized under acoustic as well as hydrodynamic cavitating conditions in addition to the optimization of the geometry of the orifice plate in the case of hydrodynamic cavitation reactors. Few experiments have also been carried out with other acid (lower and higher)/methanol combination viz. caprylic acid and capric acids with methanol with an aim of investigating the efficacy of cavitation for giving the desired yields and also to quantify the degree of process intensification that can be achieved using the same. It has been observed that ambient operating conditions of temperature and pressure and reaction times of <3h, for all the different combinations of acid (lower and higher)/methanol studied in the present work, was sufficient for giving >90% conversion (mol%). This clearly establishes the efficacy of cavitation as an excellent way to achieve process intensification of the biodiesel synthesis process.

  1. Effect of cavitation on the properties of coal-tar pitch as studied by gas-liquid chromatography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    M.I. Baikenov; T.B. Omarbekov; S.K. Amerkhanova

    2008-02-15

    The applicability of the cavitation-wave effect to coal-tar pitch processing is considered. The results of the GLC analysis of the test material before and after rotor-pulsation cavitation treatment are given. The organic matter of coal-tar pitch was found to degrade upon cavitation; as a result of this, the yields of light and medium fractions considerably increased. 5 refs., 2 figs., 4 tabs.

  2. Degradation of reactive blue 13 using hydrodynamic cavitation: Effect of geometrical parameters and different oxidizing additives.

    PubMed

    Rajoriya, Sunil; Bargole, Swapnil; Saharan, Virendra Kumar

    2017-07-01

    Decolorization of reactive blue 13 (RB13), a sulphonated azo dye, was investigated using hydrodynamic cavitation (HC). The aim of research article is to check the influence of geometrical parameters (total flow area, the ratio of throat perimeter to its cross-sectional area, throat shape and size, etc.) and configuration of the cavitating devices on decolorization of RB13 in aqueous solution. For this purpose, eight cavitating devices i.e. Circular and slit venturi, and six orifice plates having different flow area and perimeter were used in the present work. Initially, the effects of various operating parameters such as solution pH, initial dye concentration, operating inlet pressure and cavitation number on the decolorization of RB13 have been investigated, and the optimum operating conditions were found. Kinetic analysis revealed that the decolorization and mineralization of RB13 using HC followed first order reaction kinetics. Almost 47% decolorization of RB13 was achieved using only HC with slit venturi as a cavitating device at an optimum inlet pressure of 0.4MPa and pH of the solution as 2.0. It has been found that in case of orifice plates, higher decolorization rate of 4×10 -3 min -1 was achieved using orifice plate 2 (OP2) which is having higher flow area and perimeter (α=2.28). The effect of process intensifying agents (hydrogen peroxide and ferrous sulphate) and different gaseous additives (oxygen and ozone) on the extent of decolorization of RB13 were also examined. Almost 66% decolorization of RB13 was achieved using HC combined with 2Lmin -1 of oxygen and in combination with ferrous sulphate (1:3). Nearly 91% decolorization was achieved using HC combined with H 2 O 2 at an optimum molar ratio (dye:H 2 O 2 ) of 1:20 while almost complete decolorization was observed in 15min using a combination of HC and ozone at 3gh -1 ozone feed rate. Maximum 72% TOC was removed using HC coupled with 3gh -1 ozone feed rate. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Reduction in excess sludge production in a dairy wastewater treatment plant via nozzle-cavitation treatment: case study of an on-farm wastewater treatment plant.

    PubMed

    Hirooka, Kayako; Asano, Ryoki; Yokoyama, Atsushi; Okazaki, Masao; Sakamoto, Akira; Nakai, Yutaka

    2009-06-01

    Nozzle-cavitation treatment was used to reduce excess sludge production in a dairy wastewater treatment plant. During the 450-d pilot-scale membrane bioreactor (MBR) operation, when 300 l of the sludge mixed liquor (1/10 of the MBR volume) was disintegrated per day by the nozzle-cavitation treatment with the addition of sodium hydrate (final concentration: 0.01% W/W) and returned to the MBR, the amount of excess sludge produced was reduced by 80% compared with that when sludge was not disintegrated. On the basis of the efficiency of CODCr removal and the ammonia oxidation reaction, it was concluded that the nozzle-cavitation treatment did not have a negative impact on the performance of the MBR. The estimation of the inorganic material balance showed that when the mass of the excess sludge was decreased, the inorganic content of the activated sludge increased and some part of the inorganic material was simultaneously solubilized in the effluent.

  4. Developing a CD-CBM Anticipatory Approach for Cavitation - Defining a Model Descriptor Consistent Between Processes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allgood, G.O.; Dress, W.B.; Kercel, S.W.

    1999-05-10

    A major problem with cavitation in pumps and other hydraulic devices is that there is no effective method for detecting or predicting its inception. The traditional approach is to declare the pump in cavitation when the total head pressure drops by some arbitrary value (typically 3o/0) in response to a reduction in pump inlet pressure. However, the pump is already cavitating at this point. A method is needed in which cavitation events are captured as they occur and characterized by their process dynamics. The object of this research was to identify specific features of cavitation that could be used asmore » a model-based descriptor in a context-dependent condition-based maintenance (CD-CBM) anticipatory prognostic and health assessment model. This descriptor was based on the physics of the phenomena, capturing the salient features of the process dynamics. An important element of this concept is the development and formulation of the extended process feature vector @) or model vector. Thk model-based descriptor encodes the specific information that describes the phenomena and its dynamics and is formulated as a data structure consisting of several elements. The first is a descriptive model abstracting the phenomena. The second is the parameter list associated with the functional model. The third is a figure of merit, a single number between [0,1] representing a confidence factor that the functional model and parameter list actually describes the observed data. Using this as a basis and applying it to the cavitation problem, any given location in a flow loop will have this data structure, differing in value but not content. The extended process feature vector is formulated as follows: E`> [ , {parameter Iist}, confidence factor]. (1) For this study, the model that characterized cavitation was a chirped-exponentially decaying sinusoid. Using the parameters defined by this model, the parameter list included frequency, decay, and chirp rate. Based on this, the process feature vector has the form: @=> [, {01 = a, ~= b, ~ = c}, cf = 0.80]. (2) In this experiment a reversible catastrophe was examined. The reason for this is that the same catastrophe could be repeated to ensure the statistical significance of the data.« less

  5. Numerical investigation of cavitation performance on bulb tubular turbine

    NASA Astrophysics Data System (ADS)

    Sun, L. G.; Guo, P. C.; Zheng, X. B.; Luo, X. Q.

    2016-05-01

    The cavitation flow phenomena may occur in the bulb tubular turbine at some certain operation conditions, which even decrease the performance of units and causes insatiably noise and vibration when it goes worse. A steady cavitating flow numerical simulations study is carried out on the bulb tubular unit with the same blade pitch angle and different guide vane openings by using the commercial code ANSYS CFX in this paper. The phenomena of cavitation induction areas and development process are obtained and draws cavitation performance curves. The numerical results show that the travelling bubble cavity is the main types of cavitation development over a wide operating range of discharge and this type of cavitation begins to sensitive to the value of cavitation number when the discharge exceeding a certain valve, in this condition, it can lead to a severe free bubble formation with the gradually decrement of cavitation number. The reported cavitation performance curves results indicate that the flow blockage incident would happen because of a mount of free bubble formation in the flow passage when the cavity developed to certain extend, which caused head drop behavior and power broken dramatically and influenced the output power.

  6. High Speed Imaging of Cavitation around Dental Ultrasonic Scaler Tips.

    PubMed

    Vyas, Nina; Pecheva, Emilia; Dehghani, Hamid; Sammons, Rachel L; Wang, Qianxi X; Leppinen, David M; Walmsley, A Damien

    2016-01-01

    Cavitation occurs around dental ultrasonic scalers, which are used clinically for removing dental biofilm and calculus. However it is not known if this contributes to the cleaning process. Characterisation of the cavitation around ultrasonic scalers will assist in assessing its contribution and in developing new clinical devices for removing biofilm with cavitation. The aim is to use high speed camera imaging to quantify cavitation patterns around an ultrasonic scaler. A Satelec ultrasonic scaler operating at 29 kHz with three different shaped tips has been studied at medium and high operating power using high speed imaging at 15,000, 90,000 and 250,000 frames per second. The tip displacement has been recorded using scanning laser vibrometry. Cavitation occurs at the free end of the tip and increases with power while the area and width of the cavitation cloud varies for different shaped tips. The cavitation starts at the antinodes, with little or no cavitation at the node. High speed image sequences combined with scanning laser vibrometry show individual microbubbles imploding and bubble clouds lifting and moving away from the ultrasonic scaler tip, with larger tip displacement causing more cavitation.

  7. High Speed Imaging of Cavitation around Dental Ultrasonic Scaler Tips

    PubMed Central

    Vyas, Nina; Pecheva, Emilia; Dehghani, Hamid; Sammons, Rachel L.; Wang, Qianxi X.; Leppinen, David M.; Walmsley, A. Damien

    2016-01-01

    Cavitation occurs around dental ultrasonic scalers, which are used clinically for removing dental biofilm and calculus. However it is not known if this contributes to the cleaning process. Characterisation of the cavitation around ultrasonic scalers will assist in assessing its contribution and in developing new clinical devices for removing biofilm with cavitation. The aim is to use high speed camera imaging to quantify cavitation patterns around an ultrasonic scaler. A Satelec ultrasonic scaler operating at 29 kHz with three different shaped tips has been studied at medium and high operating power using high speed imaging at 15,000, 90,000 and 250,000 frames per second. The tip displacement has been recorded using scanning laser vibrometry. Cavitation occurs at the free end of the tip and increases with power while the area and width of the cavitation cloud varies for different shaped tips. The cavitation starts at the antinodes, with little or no cavitation at the node. High speed image sequences combined with scanning laser vibrometry show individual microbubbles imploding and bubble clouds lifting and moving away from the ultrasonic scaler tip, with larger tip displacement causing more cavitation. PMID:26934340

  8. Dynamic behaviors of cavitation bubble for the steady cavitating flow

    NASA Astrophysics Data System (ADS)

    Cai, Jun; Huai, Xiulan; Li, Xunfeng

    2009-12-01

    In this paper, by introducing the flow velocity item into the classical Rayleigh-Plesset dynamic equation, a new equation, which does not involve the time term and can describe the motion of cavitation bubble in the steady cavitating flow, has been obtained. By solving the new motion equation using Runge-Kutta fourth order method with adaptive step size control, the dynamic behaviors of cavitation bubble driven by the varying pressure field downstream of a venturi cavitation reactor are numerically simulated. The effects of liquid temperature (corresponding to the saturated vapor pressure of liquid), cavitation number and inlet pressure of venturi on radial motion of bubble and pressure pulse due to the radial motion are analyzed and discussed in detail. Some dynamic behaviors of bubble different from those in previous papers are displayed. In addition, the internal relationship between bubble dynamics and process intensification is also discussed. The simulation results reported in this work reveal the variation laws of cavitation intensity with the flow conditions of liquid, and will lay a foundation for the practical application of hydrodynamic cavitation technology.

  9. FOREWORD: International Symposium of Cavitation and Multiphase Flow (ISCM 2014)

    NASA Astrophysics Data System (ADS)

    Wu, Yulin

    2015-01-01

    The International Symposium on Cavitation and Multiphase Flow (ISCM 2014) was held in Beijing, China during 18th-21st October, 2014, which was jointly organized by Tsinghua University, Beijing, China and Jiangsu University, Zhenjiang, China. The co-organizer was the State Key Laboratory of Hydroscience and Engineering, Beijing, China. Cavitation and multiphase flow is one of paramount topics of fluid mechanics with many engineering applications covering a broad range of topics, e.g. hydraulic machinery, biomedical engineering, chemical and process industry. In order to improve the performances of engineering facilities (e.g. hydraulic turbines) and to accelerate the development of techniques for medical treatment of serious diseases (e.g. tumors), it is essential to improve our understanding of cavitation and Multiphase Flow. For example, the present development towards the advanced hydrodynamic systems (e.g. space engine, propeller, hydraulic machinery system) often requires that the systems run under cavitating conditions and the risk of cavitation erosion needs to be controlled. The purpose of the ISCM 2014 was to discuss the state-of-the-art cavitation and multiphase flow research and their up-to-date applications, and to foster discussion and exchange of knowledge, and to provide an opportunity for the researchers, engineers and graduate students to report their latest outputs in these fields. Furthermore, the participants were also encouraged to present their work in progress with short lead time and discuss the encountered problems. ISCM 2014 covers all aspects of cavitation and Multiphase Flow, e.g. both fundamental and applied research with a focus on physical insights, numerical modelling and applications in engineering. Some specific topics are: Cavitating and Multiphase Flow in hydroturbines, pumps, propellers etc. Numerical simulation techniques Cavitation and multiphase flow erosion and anti-erosion techniques Measurement techniques for cavitation and multiphase flow detection Fluid-structure interaction induced by cavitation and multiphase flow Multi-scale modelling of cavitating flows and Multiphase Flow Cavitation nuclei: theory and experiments Supercavitation and its applications Synergetic effects of cavitation and silt-laden erosion Shock waves and microjets generated by cavitation Nonlinear oscillations of gas and vapour bubbles Fundamentals of physics of acoustic cavitation Sonochemistry and sonoluminescence Biomedical applications of cavitation effects Ultrasonic cavitation for molten metal treatment Cavitation for enhanced heat transfer The ISCM 2014 brought together 95 scientists, researchers and graduate students from 11 countries, affiliated with universities, technology centers and industrial firms to debate topics related to advanced technologies for cavitation and Multiphase Flow, which would enhance the sustainable development of cavitation and Multiphase Flow in interdisciplinary sciences and technology. The technical committee selected 54 technical papers on the following topics: (i) Hydrodynamic Cavitation, (ii) Super Cavitation, (iii) Pump Cavitation, (iv) Acoustic Cavitation, (v) Interdisciplinary Research of Cavitation and Multi-Phase Flows, and 13 invited plenary and invited forum lectures, which were presented at the symposium, to be included in the proceedings. All the papers of ISCM 2014, which are published in this Volume of IOP Conference Series: Materials Science and Engineering, had been peer reviewed through processes administered by the editors of the ISCM 2014, those are Yulin WU, Shouqi YUAN, Zhengwei WANG, Shuhong LIU, Xingqi LUO, Fujun WANG and Guoyu WANG. The papers published in this Volume include 54 technical papers and 3 full length texts of the invited lectures. We sincerely hope that the International Symposium on Cavitation and Multiphase Flow is a significant step forward in the world wide efforts to address the present challenges in the modern science and technology. Professor Yulin WU Chairman of the Local Organizing Committee International Symposium on Cavitation and Multiphase Flow (ISCM 2014) October, 2014

  10. Continuous Cavitation Designed for Enhancing Radiofrequency Ablation via a Special Radiofrequency Solidoid Vaporization Process.

    PubMed

    Zhang, Kun; Li, Pei; Chen, Hangrong; Bo, Xiaowan; Li, Xiaolong; Xu, Huixiong

    2016-02-23

    Lowering power output and radiation time during radiofrequency (RF) ablation is still a challenge. Although it is documented that metal-based magnetothermal conversion and microbubbles-based inertial cavitation have been tried to overcome above issues, disputed toxicity and poor magnetothermal conversion efficiency for metal-based nanoparticles and violent but transient cavitation for microbubbles are inappropriate for enhancing RF ablation. In this report, a strategy, i.e., continuous cavitation, has been proposed, and solid menthol-encapsulated poly lactide-glycolide acid (PLGA) nanocapsules have been constructed, as a proof of concept, to validate the role of such a continuous cavitation principle in continuously enhancing RF ablation. The synthesized PLGA-based nanocapsules can respond to RF to generate menthol bubbles via distinctive radiofrequency solidoid vaporization (RSV) process, meanwhile significantly enhance ultrasound imaging for HeLa solid tumor, and further facilitate RF ablation via the continuous cavitation, as systematically demonstrated both in vitro and in vivo. Importantly, this RSV strategy can overcome drawbacks and limitations of acoustic droplet vaporization (ADV) and optical droplet vaporization (ODV), and will probably find broad applications in further cancer theranostics.

  11. Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation.

    PubMed

    Mah, In Kyoung; Soloff, Rachel; Izuhara, Audrey K; Lakeland, Daniel L; Wang, Charles; Mariani, Francesca V

    2016-08-01

    Polarized epithelia define boundaries, spaces, and cavities within organisms. Cavitation, a process by which multicellular hollow balls or tubes are produced, is typically associated with the formation of organized epithelia. In order for these epithelial layers to form, cells must ultimately establish a distinct apical-basal polarity. Atypical PKCs have been proposed to be required for apical-basal polarity in diverse species. Here we show that while cells null for the Prkci isozyme exhibit some polarity characteristics, they fail to properly segregate apical-basal proteins, form a coordinated ectodermal epithelium, or participate in normal cavitation. A failure to cavitate could be due to an overgrowth of interior cells or to an inability of interior cells to die. Null cells however, do not have a marked change in proliferation rate and are still capable of undergoing cell death, suggesting that alterations in these processes are not the predominant cause of the failed cavitation. Overexpression of BMP4 or EZRIN can partially rescue the phenotype possibly by promoting cell death, polarity, and differentiation. However, neither is sufficient to provide the required cues to generate a polarized epithelium and fully rescue cavitation. Interestingly, when wildtype and Prkci(-/-) ES cells are mixed together, a polarized ectodermal epithelium forms and cavitation is rescued, likely due to the ability of wildtype cells to produce non-autonomous polarity cues. We conclude that Prkci is not required for cells to respond to these cues, though it is required to produce them. Together these findings indicate that environmental cues can facilitate the formation of polarized epithelia and that cavitation requires the proper coordination of multiple basic cellular processes including proliferation, differentiation, cell death, and apical-basal polarization. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Experimental investigation of cavitation induced air release

    NASA Astrophysics Data System (ADS)

    Kowalski, Karoline; Pollak, Stefan; Hussong, Jeanette

    Variations in cross-sectional areas may lead to pressure drops below a critical value, such that cavitation and air release are provoked in hydraulic systems. Due to a relatively slow dissolution of gas bubbles, the performance of hydraulic systems will be affected on long time scales by the gas phase. Therefore predictions of air production rates are desirable to describe the system characteristics. Existing investigations on generic geometries such as micro-orifice flows show an outgassing process due to hydrodynamic cavitation which takes place on time scales far shorter than diffusion processes. The aim of the present investigation is to find a correlation between global, hydrodynamic flow characteristics and cavitation induced undissolved gas fractions generated behind generic flow constrictions such as an orifice or venturi tube. Experimental investigations are realised in a cavitation channel that enables an independent adjustment of the pressure level upstream and downstream of the orifice. Released air fractions are determined by means of shadowgraphy imaging. First results indicate that an increased cavitation activity leads to a rapid increase in undissolved gas volume only in the choking regime. The frequency distribution of generated gas bubble size seems to depend only indirectly on the cavitation intensity driven by an increase of downstream coalescence events due to a more densely populated bubbly flow.

  13. Influence of experimental parameters on sonochemistry dosimetries: KI oxidation, Fricke reaction and H2O2 production.

    PubMed

    Merouani, Slimane; Hamdaoui, Oualid; Saoudi, Fethi; Chiha, Mahdi

    2010-06-15

    Central events of the ultrasonic action are the cavitation bubbles that can be considered as microreactors. Adiabatic collapse of cavitation bubbles leads to the formation of reactive species such as hydroxyl radicals (*OH), hydrogen peroxide (H(2)O(2)) and hydroperoxyl radicals (HOO*). Several chemical methods were used to detect the production of these reactive moieties in sonochemistry. In this work, the influence of several operational parameters on the sonochemistry dosimetries namely KI oxidation, Fricke reaction and H(2)O(2) production using 300 kHz ultrasound was investigated. The main experimental parameters showing significant effect in KI oxidation dosimetry were initial KI concentration, acoustic power and pH. The solution temperature showed restricted influence on KI oxidation. The acoustic power and liquid temperature highly affected Fricke reaction dosimetry. Operational conditions having important influence on H(2)O(2) formation were acoustic power, solution temperature and pH. For the three tested dosimetries, the sonochemical efficiency was independent of liquid volume. Copyright 2010 Elsevier B.V. All rights reserved.

  14. Numerical simulation of cavitation flow characteristic on Pelton turbine bucket surface

    NASA Astrophysics Data System (ADS)

    Zeng, C. J.; Xiao, Y. X.; Zhu, W.; Yao, Y. Y.; Wang, Z. W.

    2015-01-01

    The internal flow in the rotating bucket of Pelton turbine is free water sheet flow with moving boundary. The runner operates under atmospheric and the cavitation in the bucket is still a controversial problem. While more and more field practice proved that there exists cavitation in the Pelton turbine bucket and the cavitation erosion may occur at the worst which will damage the bucket. So a well prediction about the cavitation flow on the bucket surface of Pelton turbine and the followed cavitation erosion characteristic can effectively guide the optimization of Pelton runner bucket and the stable operation of unit. This paper will investigate the appropriate numerical model and method for the unsteady 3D water-air-vapour multiphase cavitation flow which may occur on the Pelton bucket surface. The computational domain will include the nozzle pipe flow, semi-free surface jet and runner domain. Via comparing the numerical results of different turbulence, cavity and multiphase models, this paper will determine the suitable numerical model and method for the simulation of cavitation on the Pelton bucket surface. In order to investigate the conditions corresponding to the cavitation phenomena on the bucket surface, this paper will adopt the suitable model to simulate the various operational conditions of different water head and needle travel. Then, the characteristics of cavitation flow the development process of cavitation will be analysed in in great detail.

  15. Treatment of cyanide containing wastewater using cavitation based approach.

    PubMed

    Jawale, Rajashree H; Gogate, Parag R; Pandit, Aniruddha B

    2014-07-01

    Industrial wastewater streams containing high concentrations of biorefractory materials like cyanides should ideally be treated at source. In the present work, degradation of potassium ferrocyanide (K4Fe(CN)6) as a model pollutant has been investigated using cavitational reactors with possible intensification studies using different approaches. Effect of different operating parameters such as initial concentration, temperature and pH on the extent of degradation using acoustic cavitation has been investigated. For the case of hydrodynamic cavitation, flow characteristics of cavitating device (venturi) have been established initially followed by the effect of inlet pressure and pH on the extent of degradation. Under the optimized set of operating parameters, the addition of hydrogen peroxide (ratio of K4Fe(CN)6:H2O2 varied from 1:1 to 1:30 mol basis) as process intensifying approach has been investigated. The present work has conclusively established that under the set of optimized operating parameters, cavitation can be effectively used for degradation of potassium ferrocyanide. The comparative study of hydrodynamic cavitation and acoustic cavitation suggested that hydrodynamic cavitation is more energy efficient and gives higher degradation as compared to acoustic cavitation for equivalent power/energy dissipation. The present work is the first one to report comparison of cavitation based treatment schemes for degradation of cyanide containing wastewaters. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Spatial-temporal three-dimensional ultrasound plane-by-plane active cavitation mapping for high-intensity focused ultrasound in free field and pulsatile flow.

    PubMed

    Ding, Ting; Hu, Hong; Bai, Chen; Guo, Shifang; Yang, Miao; Wang, Supin; Wan, Mingxi

    2016-07-01

    Cavitation plays important roles in almost all high-intensity focused ultrasound (HIFU) applications. However, current two-dimensional (2D) cavitation mapping could only provide cavitation activity in one plane. This study proposed a three-dimensional (3D) ultrasound plane-by-plane active cavitation mapping (3D-UPACM) for HIFU in free field and pulsatile flow. The acquisition of channel-domain raw radio-frequency (RF) data in 3D space was performed by sequential plane-by-plane 2D ultrafast active cavitation mapping. Between two adjacent unit locations, there was a waiting time to make cavitation nuclei distribution of the liquid back to the original state. The 3D cavitation map equivalent to the one detected at one time and over the entire volume could be reconstructed by Marching Cube algorithm. Minimum variance (MV) adaptive beamforming was combined with coherence factor (CF) weighting (MVCF) or compressive sensing (CS) method (MVCS) to process the raw RF data for improved beamforming or more rapid data processing. The feasibility of 3D-UPACM was demonstrated in tap-water and a phantom vessel with pulsatile flow. The time interval between temporal evolutions of cavitation bubble cloud could be several microseconds. MVCF beamformer had a signal-to-noise ratio (SNR) at 14.17dB higher, lateral and axial resolution at 2.88times and 1.88times, respectively, which were compared with those of B-mode active cavitation mapping. MVCS beamformer had only 14.94% time penalty of that of MVCF beamformer. This 3D-UPACM technique employs the linear array of a current ultrasound diagnosis system rather than a 2D array transducer to decrease the cost of the instrument. Moreover, although the application is limited by the requirement for a gassy fluid medium or a constant supply of new cavitation nuclei that allows replenishment of nuclei between HIFU exposures, this technique may exhibit a useful tool in 3D cavitation mapping for HIFU with high speed, precision and resolution, especially in a laboratory environment where more careful analysis may be required under controlled conditions. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. Novel cavitation fluid jet polishing process based on negative pressure effects.

    PubMed

    Chen, Fengjun; Wang, Hui; Tang, Yu; Yin, Shaohui; Huang, Shuai; Zhang, Guanghua

    2018-04-01

    Traditional abrasive fluid jet polishing (FJP) is limited by its high-pressure equipment, unstable material removal rate, and applicability to ultra-smooth surfaces because of the evident air turbulence, fluid expansion, and a large polishing spot in high-pressure FJP. This paper presents a novel cavitation fluid jet polishing (CFJP) method and process based on FJP technology. It can implement high-efficiency polishing on small-scale surfaces in a low-pressure environment. CFJP uses the purposely designed polishing equipment with a sealed chamber, which can generate a cavitation effect in negative pressure environment. Moreover, the collapse of cavitation bubbles can spray out a high-energy microjet and shock wave to enhance the material removal. Its feasibility is verified through researching the flow behavior and the cavitation results of the negative pressure cavitation machining of pure water in reversing suction flow. The mechanism is analyzed through a computational fluid dynamics simulation. Thus, its cavitation and surface removal mechanisms in the vertical CFJP and inclined CFJP are studied. A series of polishing experiments on different materials and polishing parameters are conducted to validate its polishing performance compared with FJP. The maximum removal depth increases, and surface roughness gradually decreases with increasing negative outlet pressures. The surface becomes smooth with the increase of polishing time. The experimental results confirm that the CFJP process can realize a high material removal rate and smooth surface with low energy consumption in the low-pressure environment, together with compatible surface roughness to FJP. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Quantitative Frequency-Domain Passive Cavitation Imaging

    PubMed Central

    Haworth, Kevin J.; Bader, Kenneth B.; Rich, Kyle T.; Holland, Christy K.; Mast, T. Douglas

    2017-01-01

    Passive cavitation detection has been an instrumental technique for measuring cavitation dynamics, elucidating concomitant bioeffects, and guiding ultrasound therapies. Recently, techniques have been developed to create images of cavitation activity to provide investigators with a more complete set of information. These techniques use arrays to record and subsequently beamform received cavitation emissions, rather than processing emissions received on a single-element transducer. In this paper, the methods for performing frequency-domain delay, sum, and integrate passive imaging are outlined. The method can be applied to any passively acquired acoustic scattering or emissions, including cavitation emissions. In order to compare data across different systems, techniques for normalizing Fourier transformed data and converting the data to the acoustic energy received by the array are described. A discussion of hardware requirements and alternative imaging approaches are additionally outlined. Examples are provided in MATLAB. PMID:27992331

  19. Optical observation of shock waves and cavitation bubbles in high intensity laser-induced shock processes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marti-Lopez, L.; Ocana, R.; Porro, J. A.

    2009-07-01

    We report an experimental study of the temporal and spatial dynamics of shock waves, cavitation bubbles, and sound waves generated in water during laser shock processing by single Nd:YAG laser pulses of nanosecond duration. A fast ICCD camera (2 ns gate time) was employed to record false schlieren photographs, schlieren photographs, and Mach-Zehnder interferograms of the zone surrounding the laser spot site on the target, an aluminum alloy sample. We recorded hemispherical shock fronts, cylindrical shock fronts, plane shock fronts, cavitation bubbles, and phase disturbance tracks.

  20. Alternative Gas Mixtures in Arc Spraying: A Chance to Improve Coating Properties and Residual Stress States

    NASA Astrophysics Data System (ADS)

    Hauer, Michél; Henkel, Knuth Michael; Krebs, Sebastian; Kroemmer, Werner

    2018-01-01

    The highly cavitation erosion-resistant propeller alloys CuAl9Ni5Fe4Mn (Ni-Al-Bronze) and CuMn13Al8Fe3Ni2 (Mn-Al-Bronze) were arc-sprayed using a mixture of nitrogen and 2% of hydrogen as atomizing gas and different traverse speeds. The objective was to identify the influences of the different spraying conditions, such as temperature regime and melting loss, on the resulting residual stress states and coating properties. Residual stresses were measured by the incremental hole-drilling method using ESPI. Temperature measurements were carried out by thermographic imaging. Microstructural, chemical and mechanical analyses were realized to examine adhesive and cohesive properties. Additionally, the cavitation erosion behavior was investigated to analyze cohesive coating properties. The spraying process itself was improved, which was apparent by mainly enhanced deposition efficiency and reduced surface temperatures. The amount of oxides and pores as well as the melting loss of alloying elements were reduced. Moreover, an increased cavitation erosion resistance and thus coating cohesion as well as less residual stresses were identified. The change in atomizing gas diminished the impact of the quenching stresses on the coating properties. In contrast, the adhesive strength, Young's moduli and partially the hardness were slightly reduced. With regard to materials, Ni-Al-Bronze revealed superior coating properties in comparison with Mn-Al-Bronze.

  1. Study of Anti-Vortex Baffle Effect in Suppressing Swirling Flow in LOX Tank

    NASA Technical Reports Server (NTRS)

    Yang, H. Q.; Peugeot, John

    2011-01-01

    Experimental results describing the hydraulic dynamic pump transfer matrix (Yp) for a cavitating J-2X oxidizer turbopump inducer+impeller tested in subscale waterflow are presented. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Dynamic transfer functions across widely varying pump hydrodynamic inlet conditions are extracted from measured data in conjunction with 1D-model based corrections. Derived Dynamic transfer functions are initially interpreted relative to traditional Pogo pump equations. Water-to-liquid oxygen scaling of measured cavitation characteristics are discussed. Comparison of key dynamic transfer matrix terms derived from waterflow testing are made with those implemented in preliminary Ares Upper Stage Pogo stability modeling. Alternate cavitating pump hydraulic dynamic equations are suggested which better reflect frequency dependencies of measured transfer matrices.

  2. The influence of surface roughness on cloud cavitation flow around hydrofoils

    NASA Astrophysics Data System (ADS)

    Hao, Jiafeng; Zhang, Mindi; Huang, Xu

    2018-02-01

    The aim of this study is to investigate experimentally the effect of surface roughness on cloud cavitation around Clark-Y hydrofoils. High-speed video and particle image velocimetry (PIV) were used to obtain cavitation patterns images (Prog. Aerosp. Sci. 37: 551-581, 2001), as well as velocity and vorticity fields. Results are presented for cloud cavitating conditions around a Clark-Y hydrofoil fixed at angle of attack of α =8{°} for moderate Reynolds number of Re=5.6 × 105. The results show that roughness had a great influence on the pattern, velocity and vorticity distribution of cloud cavitation. For cavitating flow around a smooth hydrofoil (A) and a rough hydrofoil (B), cloud cavitation occurred in the form of finger-like cavities and attached subulate cavities, respectively. The period of cloud cavitation around hydrofoil A was shorter than for hydrofoil B. Surface roughness had a great influence on the process of cloud cavitation. The development of cloud cavitation around hydrofoil A consisted of two stages: (1) Attached cavities developed along the surface to the trailing edge; (2) A reentrant jet developed, resulting in shedding and collapse of cluster bubbles or vortex structure. Meanwhile, its development for hydrofoil B included three stages: (1) Attached cavities developed along the surface to the trailing edge, with accumulation and rotation of bubbles at the trailing edge of the hydrofoil affecting the flow field; (2) Development of a reentrant jet resulted in the first shedding of cavities. Interaction and movement of flows from the pressure side and suction side brought liquid water from the pressure side to the suction side of the hydrofoil, finally forming a reentrant jet. The jet kept moving along the surface to the leading edge of the hydrofoil, resulting in large-scale shedding of cloud bubbles. Several vortices appeared and dissipated during the process; (3) Cavities grew and shed again.

  3. Tip Vortex Cavitation

    NASA Astrophysics Data System (ADS)

    Maines, Brant H.; Arndt, Roger E. A.

    2000-11-01

    Cavitation in vortical flows is a problem of practical importance, that is relatively unexplored. Vortical structures of importance range from the eddies occurring randomly in space and time in turbulent flows to the developed vortices that occur at the tips of lifting surfaces and at the hubs of propellers and hydraulic turbines. A variety of secondary flow phenomena such as the horse shoe vortices that form around bridge piers, chute blocks and struts, and the secondary vortices found in the clearance passages of turbomachinery are also important cavitation sites. Tip vortex cavitation can be viewed as a canonical problem that captures many of the essential physics associated with vortex cavitation in general. This paper describes the inception process and focuses on the high levels of tension that can be sustained in the flow, which appears to scale with the blade loading. High speed video visualization indicates that the details of how free stream nuclei are ingested plays a major role in the nucleation and inception process. A new photographic technique was used to obtain high quality images of the bubble growth process at framing rates as high as 40,000 fps. Sponsored by the Office of Naval Research

  4. Time-resolved monitoring of cavitation activity in megasonic cleaning systems.

    PubMed

    Hauptmann, M; Brems, S; Struyf, H; Mertens, P; Heyns, M; De Gendt, S; Glorieux, C

    2012-03-01

    The occurrence of acoustic cavitation in the cleaning liquid is a crucial precondition for the performance of megasonic cleaning systems. Hence, a fundamental understanding of the impact of different parameters of the megasonic process on cavitation activity is necessary. A setup capable of synchronously measuring sonoluminescence and acoustic emission originating from acoustically active bubbles is presented. The system also includes a high-speed-stroboscopic Schlieren imaging system to directly visualize the influence of cavitation activity on the Schlieren contrast and resolvable bubbles. This allows a thorough characterization of the mutual interaction of cavitation bubbles with the sound field and with each other. Results obtained during continuous sonication of argon-saturated water at various nominal power densities indicate that acoustic cavitation occurs in a cyclic manner, during which periods of stable and inertial cavitation activity alternate. The occurrence of higher and ultraharmonics in the acoustic emission spectra is characteristic for the stable cavitation state. The inertial cavitation state is characterized by a strong attenuation of the sound field, the explosive growth of bubbles and the occurrence of broadband components in the acoustic spectra. Both states can only be sustained at sufficiently high intensities of the sound field. At lower intensities, their occurrences are limited to short, random bursts. Cleaning activity can be linked to the cavitation activity through the measurement of particle removal on standard 200 mm silicon wafers. It is found that the particle removal efficiency is reduced, when a continuous state of cavitation activity ceases to exist.

  5. Numerical simulation on the cavitation of waterjet propulsion pump

    NASA Astrophysics Data System (ADS)

    Xia, C. Z.; Cheng, L.; Shang, Y. N.; Zhou, J. R.; Yang, F.; Jin, Y.

    2016-05-01

    Waterjet propulsion system is widely used in high speed vessels with advantages of simple transmission mechanism, low noise underwater and good manoeuvrability. Compared with the propeller, waterjet propulsion can be used flow stamping to increasing cavitation resistance at high speed. But under certain conditions, such as low ship speed or high ship speed, cavitation problem still exists. If water-jet propulsion pump is run in cavitation condition for a long time, then the cavitation will cause a great deal of noise CFD is applied to analysis and predict the process of production and development of cavitation in waterjet propulsion pump. Based on the cavitation model of Zwart-Gerber-Belamri and a mixture of homogeneous flow model, commercial CFD software CFX was taken for characteristics of cavitation under the three operating conditions. Commercial software ANSYS 14.0 is used to build entity model, mesh and numerical simulation. The grid independence analysis determine the grid number of mixed flow pump model is about 1.6 million and the grid number of water-jet pump system unit is about 2.7 million. The cavitation characteristics of waterjet pump under three operating conditions are studied. The results show that the cavitation development trend is similar design and small rate of flow condition .Under the design conditions Cavitation bubbles are mainly gathered in suction surface of blade near the inlet side of the hub under the primary stage, and gradually extended to the water side in the direction of the rim with the loss of the inlet total pressure. Cavitation appears in hub before the blade rim, but the maximum value of gas content in blade rim is bigger than that in hub. Under large flow conditions, bubble along the direction of wheel hub extends to the rim gradually. Cavitation is found in the pressure surface of blade near the hub region under the critical point of cavitation nearby. When NPSHa is lower than critical point, the area covering by bubbles is about 40% in the suction surface of blade. It means that the critical point of cavitation of pump system is not the accrue point of install cavitation but cavitation has been developed to a certain stage.

  6. Augmentation of limb perfusion and reversal of tissue ischemia produced by ultrasound-mediated microbubble cavitation.

    PubMed

    Belcik, J Todd; Mott, Brian H; Xie, Aris; Zhao, Yan; Kim, Sajeevani; Lindner, Nathan J; Ammi, Azzdine; Linden, Joel M; Lindner, Jonathan R

    2015-04-01

    Ultrasound can increase tissue blood flow, in part, through the intravascular shear produced by oscillatory pressure fluctuations. We hypothesized that ultrasound-mediated increases in perfusion can be augmented by microbubble contrast agents that undergo ultrasound-mediated cavitation and sought to characterize the biological mediators. Contrast ultrasound perfusion imaging of hindlimb skeletal muscle and femoral artery diameter measurement were performed in nonischemic mice after unilateral 10-minute exposure to intermittent ultrasound alone (mechanical index, 0.6 or 1.3) or ultrasound with lipid microbubbles (2×10(8) IV). Studies were also performed after inhibiting shear- or pressure-dependent vasodilator pathways, and in mice with hindlimb ischemia. Ultrasound alone produced a 2-fold increase (P<0.05) in muscle perfusion regardless of ultrasound power. Ultrasound-mediated augmentation in flow was greater with microbubbles (3- and 10-fold higher than control for mechanical index 0.6 and 1.3, respectively; P<0.05), as was femoral artery dilation. Inhibition of endothelial nitric oxide synthase attenuated flow augmentation produced by ultrasound and microbubbles by 70% (P<0.01), whereas inhibition of adenosine-A2a receptors and epoxyeicosatrienoic acids had minimal effect. Limb nitric oxide production and muscle phospho-endothelial nitric oxide synthase increased in a stepwise fashion by ultrasound and ultrasound with microbubbles. In mice with unilateral hindlimb ischemia (40%-50% reduction in flow), ultrasound (mechanical index, 1.3) with microbubbles increased perfusion by 2-fold to a degree that was greater than the control nonischemic limb. Increases in muscle blood flow during high-power ultrasound are markedly amplified by the intravascular presence of microbubbles and can reverse tissue ischemia. These effects are most likely mediated by cavitation-related increases in shear and activation of endothelial nitric oxide synthase. © 2015 American Heart Association, Inc.

  7. Coherent-Phase Monitoring Of Cavitation In Turbomachines

    NASA Technical Reports Server (NTRS)

    Jong, Jen-Yi

    1996-01-01

    Digital electronic signal-processing system analyzes outputs of accelerometers mounted on turbomachine to detect vibrations characteristic of cavitation. Designed to overcome limitation imposed by interference from discrete components. System digitally implements technique called "coherent-phase wide-band demodulation" (CPWBD), using phase-only (PO) filtering along envelope detection to search for unique coherent-phase relationship associated with cavitation and to minimize influence of large-amplitude discrete components.

  8. Lamellar Thickness and Stretching Temperature Dependency of Cavitation in Semicrystalline Polymers

    PubMed Central

    Wang, Yaotao; Jiang, Zhiyong; Fu, Lianlian; Lu, Ying; Men, Yongfeng

    2014-01-01

    Polybutene-1 (PB-1), a typical semicrystalline polymer, in its stable form I shows a peculiar temperature dependent strain-whitening behavior when being stretched at temperatures in between room temperature and melting temperature of the crystallites where the extent of strain-whitening weakens with the increasing of stretching temperature reaching a minima value followed by an increase at higher stretching temperatures. Correspondingly, a stronger strain-hardening phenomenon was observed at higher temperatures. The strain-whitening phenomenon in semicrystalline polymers has its origin of cavitation process during stretching. In this work, the effect of crystalline lamellar thickness and stretching temperature on the cavitation process in PB-1 has been investigated by means of combined synchrotron ultrasmall-angle and wide-angle X-ray scattering techniques. Three modes of cavitation during the stretching process can be identified, namely “no cavitation” for the quenched sample with the thinnest lamellae where only shear yielding occurred, “cavitation with reorientation” for the samples stretched at lower temperatures and samples with thicker lamellae, and “cavitation without reorientation” for samples with thinner lamellae stretched at higher temperatures. The mode “cavitation with reorientation” occurs before yield point where the plate-like cavities start to be generated within the lamellar stacks with normal perpendicular to the stretching direction due to the blocky substructure of the crystalline lamellae and reorient gradually to the stretching direction after strain-hardening. The mode of “cavitation without reorientation” appears after yield point where ellipsoidal shaped cavities are generated in those lamellae stacks with normal parallel to the stretching direction followed by an improvement of their orientation at larger strains. X-ray diffraction results reveal a much improved crystalline orientation for samples with thinner lamellae stretched at higher temperatures. The observed behavior of microscopic structural evolution in PB-1 stretched at different temperatures explains above mentioned changes in macroscopic strain-whitening phenomenon with increasing in stretching temperature and stress-strain curves. PMID:24820772

  9. Chemical reactions at aqueous interfaces

    NASA Astrophysics Data System (ADS)

    Vecitis, Chad David

    2009-12-01

    Interfaces or phase boundaries are a unique chemical environment relative to individual gas, liquid, or solid phases. Interfacial reaction mechanisms and kinetics are often at variance with homogeneous chemistry due to mass transfer, molecular orientation, and catalytic effects. Aqueous interfaces are a common subject of environmental science and engineering research, and three environmentally relevant aqueous interfaces are investigated in this thesis: 1) fluorochemical sonochemistry (bubble-water), 2) aqueous aerosol ozonation (gas-water droplet), and 3) electrolytic hydrogen production and simultaneous organic oxidation (water-metal/semiconductor). Direct interfacial analysis under environmentally relevant conditions is difficult, since most surface-specific techniques require relatively `extreme' conditions. Thus, the experimental investigations here focus on the development of chemical reactors and analytical techniques for the completion of time/concentration-dependent measurements of reactants and their products. Kinetic modeling, estimations, and/or correlations were used to extract information on interfacially relevant processes. We found that interfacial chemistry was determined to be the rate-limiting step to a subsequent series of relatively fast homogeneous reactions, for example: 1) Pyrolytic cleavage of the ionic headgroup of perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) adsorbed to cavitating bubble-water interfaces during sonolysis was the rate-determining step in transformation to their inorganic constituents carbon monoxide, carbon dioxide, and fluoride; 2) ozone oxidation of aqueous iodide to hypoiodous acid at the aerosol-gas interface is the rate-determining step in the oxidation of bromide and chloride to dihalogens; 3) Electrolytic oxidation of anodic titanol surface groups is rate-limiting for the overall oxidation of organics by the dichloride radical. We also found chemistry unique to the interface, for example: 1) Adsorption of dilute PFOS(aq) and PFOA(aq) to acoustically cavitating bubble interfaces was greater than equilibrium expectations due to high-velocity bubble radial oscillations; 2) Relative ozone oxidation kinetics of aqueous iodide, sulfite, and thiosulfate were at variance with previously reported bulk aqueous kinetics; 3) Organics that directly chelated with the anode surface were oxidized by direct electron transfer, resulting in immediate carbon dioxide production but slower overall oxidation kinetics. Chemical reactions at aqueous interfaces can be the rate-limiting step of a reaction network and often display novel mechanisms and kinetics as compared to homogeneous chemistry.

  10. Application of Technology of Hydrodynamic Cavitation Processing High-Viscosity Oils for the Purpose of Improving the Rheological Characteristics of Oils

    NASA Astrophysics Data System (ADS)

    Zemenkov, Y. D.; Zemenkova, M. Y.; Vengerov, A. A.; Brand, A. E.

    2016-10-01

    There is investigated the technology of hydrodynamic cavitational processing viscous and high-viscosity oils and the possibility of its application in the pipeline transport system for the purpose of increasing of rheological properties of the transported oils, including dynamic viscosity shear stress in the article. It is considered the possibility of application of the combined hydrodynamic cavitational processing with addition of depressor additive for identification of effect of a synergism. It is developed the laboratory bench and they are presented results of modeling and laboratory researches. It is developed the hardware and technological scheme of application of the developed equipment at industrial objects of pipeline transport.

  11. Hydrodynamic cavitation: from theory towards a new experimental approach

    NASA Astrophysics Data System (ADS)

    Lucia, Umberto; Gervino, Gianpiero

    2009-09-01

    Hydrodynamic cavitation is analysed by a global thermodynamics principle following an approach based on the maximum irreversible entropy variation that has already given promising results for open systems and has been successfully applied in specific engineering problems. In this paper we present a new phenomenological method to evaluate the conditions inducing cavitation. We think this method could be useful in the design of turbo-machineries and related technologies: it represents both an original physical approach to cavitation and an economical saving in planning because the theoretical analysis could allow engineers to reduce the experimental tests and the costs of the design process.

  12. Microgravity Experiment: The Fate of Confined Shock Waves

    NASA Astrophysics Data System (ADS)

    Kobel, P.; Obreschkow, D.; Dorsaz, N.; de Bosset, A.; Farhat, M.

    2007-11-01

    Shockwave induced cavitation is a form of hydrodynamic cavitation generated by the interaction of shock waves with vapor nuclei and microscopic impurities. Both the shock waves and the induced cavitation are known as sources of erosion damage in hydraulic industrial systems and hence represent an important research topic in fluid dynamics. Here we present the first investigation of shock wave induced cavitation inside closed and isolated liquid volumes, which confine the shock wave by reflections and thereby promise a particularly strong coupling with cavitation. A microgravity platform (ESA, 42^nd parabolic flight campaign) was used to produce stable water drops with centimetric diameters. Inside these drops, a fast electrical discharge was generated to release a strong shock wave. This setting results in an amplified form of shockwave induced cavitation, visible in high-speed images as a transient haze of sub-millimetric bubbles synchronized with the shockwave radiation. A comparison between high-speed visualizations and 3D simulations of a shock front inside a liquid sphere reveals that focus zones within the drop lead to a significantly increased density of induced cavitation. Considering shock wave crossing and focusing may hence prove crucially useful to understand the important process of cavitation erosion.

  13. Inactivation of food spoilage microorganisms by hydrodynamic cavitation to achieve pasteurization and sterilization of fluid foods.

    PubMed

    Milly, P J; Toledo, R T; Harrison, M A; Armstead, D

    2007-11-01

    Hydrodynamic cavitation is the formation of gas bubbles in a fluid due to pressure fluctuations induced by mechanical means. Various high-acid (pH < [corrected]/= 4.6) fluid foods were processed in a hydrodynamic cavitation reactor to determine if commercial sterility can be achieved at reduced processing temperatures. Sporicidal properties of the process were also tested on a low-acid (pH > [corrected] 4.6) fluid food. Fluid foods were pumped under pressure into a hydrodynamic cavitation reactor and subjected to 2 rotor speeds and flow rates to achieve 2 designated exit temperatures. Thermal inactivation kinetics were used to determine heat-induced lethality for all organisms. Calcium-fortified apple juice processed at 3000 and 3600 rpm rotor speeds on the reactor went through a transient temperature change from 20 to 65.6 or 76.7 degrees C and the total process lethality exceeded 5-log reduction of Lactobacillus plantarum and Lactobacillus sakei cells, and Zygosaccharomyces bailii cells and ascospores. Tomato juice inoculated with Bacillus coagulans spores and processed at 3000 and 3600 rpm rotor speeds endured a transient temperature from 37.8 to 93.3 or 104.4 degrees C with viable CFU reductions of 0.88 and 3.10 log cycles, respectively. Skim milk inoculated with Clostridium sporogenes putrefactive anaerobe 3679 spores and processed at 3000 or 3600 rpm rotor speeds endured a transient temperature from 48.9 to 104.4 or 115.6 degrees C with CFU reductions of 0.69 and 2.84 log cycles, respectively. Utilizing hydrodynamic cavitation to obtain minimally processed pasteurized low-acid and commercially sterilized high-acid fluid foods is possible with appropriate process considerations for different products.

  14. The Enhancement of H2O2/UV AOPs for the Removal of Selected Organic Pollutants from Drinking Water with Hydrodynamic Cavitation.

    PubMed

    Čehovin, Matej; Medic, Alojz; Kompare, Boris; Žgajnar Gotvajn, Andreja

    2016-12-01

    Drinking water contains organic matter that occasionally needs to be treated to assure its sufficient quality and safety for the consumers. H2O2 and UV advanced oxidation processes (H2O2/UV AOPs) were combined with hydrodynamic cavitation (HC) to assess the effects on the removal of selected organic pollutants. Water samples containing humic acid, methylene blue dye and micropollutants (metaldehyde, diatrizoic acid, iohexol) were treated first by H2O2 (dosages from 1 to 12 mg L-1) and UV (dosages from 300 to 2800 mJ cm-2) AOPs alone and later in combination with HC, generated by nozzles and orifice plates (4, 8, 18 orifices). Using HC, the removal of humic acid was enhanced by 5-15%, methylene blue by 5-20% and metaldehyde by approx. 10%. Under favouring conditions, i.e. high UV absorbance of the matrix (more than 0.050 cm-1 at a wavelength of 254 nm) and a high pollutant to oxidants ratio, HC was found to improve the hydrodynamic conditions in the photolytic reactor, to improve the subjection of the H2O2 to the UV fluence rate distribution and to enhance the removal of the tested organic pollutants, thus showing promising potential of further research in this field.

  15. Assessment of Cavitation-Erosion Resistance of 316LN Stainless Steel Following a Nitro-Carburizing Surface Treatment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pawel, Steven J

    2009-11-01

    A nitro-carburizing surface treatment known domestically as the Melonite process was applied to type 316LN stainless steel test pieces and exposed to sonication conditions in mercury using a vibratory horn technique. Cavitation-erosion damage was evaluated for extended exposures and compared to other surface treatments on the same substrate alloy. The results indicate that the Melonite process substantially retards weight loss and crater development for extended periods, but gradually is eroded/destroyed leading to exposure of the substrate and cavitation-erosion behavior similar to untreated specimens. Compared with other surface treatments, cavitation-erosion results indicate that specimens treated with Melonite perform similarly to specimensmore » treated with a simple nitriding process. Neither the simple nitriding nor the Melonite treatment is quite as effective as a previously evaluated low temperature carburizing treatment, the latter being about a factor of three better than Melonite in terms of weight loss during sonication in mercury.« less

  16. Process to restore obliterated serial numbers on metal surfaces

    NASA Technical Reports Server (NTRS)

    Young, S. G.; Parker, B.; Chisum, W. J.

    1974-01-01

    Metal smeared into grooves of serial numbers by grinding or filing can be cleaned out by process called cavitation. Ultrasonic vibrator generates very high frequency vibrations in water which create millions of microscopic bubbles. Cavitation bubbles impact metal surface at thousands of pounds per square inch pressure. Metal particles filling grooves are broken away.

  17. Harmonic responses and cavitation activity of encapsulated microbubbles coupled with magnetic nanoparticles.

    PubMed

    Gu, Yuyang; Chen, Chuyi; Tu, Juan; Guo, Xiasheng; Wu, Hongyi; Zhang, Dong

    2016-03-01

    Encapsulated microbubbles coupled with magnetic nanoparticles, one kind of hybrid agents that can integrate both ultrasound and magnetic resonance imaging/therapy functions, have attracted increasing interests in both research and clinic communities. However, there is a lack of comprehensive understanding of their dynamic behaviors generated in diagnostic and therapeutic applications. In the present work, a hybrid agent was synthesized by integrating superparamagnetic iron oxide nanoparticles (SPIOs) into albumin-shelled microbubbles (named as SPIO-albumin microbubbles). Then, both the stable and inertial cavitation thresholds of this hybrid agent were measured at varied SPIO concentrations and ultrasound parameters (e.g., frequency, pressure amplitude, and pulse length). The results show that, at a fixed acoustic driving frequency, both the stable and inertial cavitation thresholds of SPIO-albumin microbubble should decrease with the increasing SPIO concentration and acoustic driving pulse length. The inertial cavitation threshold of SPIO-albumin microbubbles also decreases with the raised driving frequency, while the minimum sub- and ultra-harmonic thresholds appear at twice and two thirds resonance frequency, respectively. It is also noticed that both the stable and inertial cavitation thresholds of SonoVue microbubbles are similar to those measured for hybrid microbubbles with a SPIO concentration of 114.7 μg/ml. The current work could provide better understanding on the impact of the integrated SPIOs on the dynamic responses (especially the cavitation activities) of hybrid microbubbles, and suggest the shell composition of hybrid agents should be appropriately designed to improve their clinical diagnostic and therapeutic performances of hybrid microbubble agents. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Synergetic effect of combination of AOP's (hydrodynamic cavitation and H₂O₂) on the degradation of neonicotinoid class of insecticide.

    PubMed

    Raut-Jadhav, Sunita; Saharan, Virendra Kumar; Pinjari, Dipak; Sonawane, Shirish; Saini, Daulat; Pandit, Aniruddha

    2013-10-15

    In the present work, degradation of imidacloprid (neonicotinoid class of insecticide) in aqueous solution has been systematically investigated using hydrodynamic cavitation and combination of hydrodynamic cavitation (HC) and H2O2. Initially, effect of different operating parameters such as inlet pressure to the cavitating device (5-20 bar) and operating pH (2-7.5) has been investigated. Optimization of process parameters was followed by the study of effect of combination of HC and H2O2 process on the rate of degradation of imidacloprid. Significant enhancement in the rate of degradation of imidacloprid has been observed using HC+H2O2 process which lead to a complete degradation of imidacloprid in 45 min of operation using optimal molar ratio of imidacloprid:H2O2 as 1:40. Substantial synergetic effect has been observed using HC+H2O2 process which confer the synergetic coefficient of 22.79. An attempt has been made to investigate and compare the energy efficiency and extent of mineralization of individual and combined processes applied in the present work. Identification of the byproducts formed during degradation of imidacloprid has also been done using LC-MS analysis. The present work has established a fact that hydrodynamic cavitation in combination with H2O2 can be effectively used for degradation of imidacloprid. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. Enhancing the aggressive intensity of hydrodynamic cavitation through a Venturi tube by increasing the pressure in the region where the bubbles collapse

    NASA Astrophysics Data System (ADS)

    Soyama, H.; Hoshino, J.

    2016-04-01

    In this paper, we used a Venturi tube for generating hydrodynamic cavitation, and in order to obtain the optimum conditions for this to be used in chemical processes, the relationship between the aggressive intensity of the cavitation and the downstream pressure where the cavitation bubbles collapse was investigated. The acoustic power and the luminescence induced by the bubbles collapsing were investigated under various cavitating conditions, and the relationships between these and the cavitation number, which depends on the upstream pressure, the downstream pressure at the throat of the tube and the vapor pressure of the test water, was found. It was shown that the optimum downstream pressure, i.e., the pressure in the region where the bubbles collapse, increased the aggressive intensity by a factor of about 100 compared to atmospheric pressure without the need to increase the input power. Although the optimum downstream pressure varied with the upstream pressure, the cavitation number giving the optimum conditions was constant for all upstream pressures.

  20. Cavitation Erosion in Hydraulic Turbine Components and Mitigation by Coatings: Current Status and Future Needs

    NASA Astrophysics Data System (ADS)

    Singh, Raghuvir; Tiwari, S. K.; Mishra, Suman K.

    2012-07-01

    Cavitation erosion is a frequently observed phenomenon in underwater engineering materials and is the primary reason for component failure. The damage due to cavitation erosion is not yet fully understood, as it is influenced by several parameters, such as hydrodynamics, component design, environment, and material chemistry. This article gives an overview of the current state of understanding of cavitation erosion of materials used in hydroturbines, coatings and coating methodologies for combating cavitation erosion, and methods to characterize cavitation erosion. No single material property fully characterizes the resistance to cavitation erosion. The combination of ultimate resilience, hardness, and toughness rather may be useful to estimate the cavitation erosion resistance of material. Improved hydrodynamic design and appropriate surface engineering practices reduce damage due to cavitation erosion. The coatings suggested for combating the cavitation erosion encompasses carbides (WC Cr2C3, Cr3C2, 20CrC-80WC), cermets of different compositions (e.g., 56W2C/Ni/Cr, 41WC/Ni/Cr/Co), intermetallic composites, intermetallic matrix composites with TiC reinforcement, composite nitrides such as TiAlN and elastomers. A few of them have also been used commercially. Thermal spraying, arc plasma spraying, and high velocity oxy-fuel (HVOF) processes have been used commercially to apply the coatings. Boronizing, laser surface hardening and cladding, chemical vapor deposition, physical vapor deposition, and plasma nitriding have been tried for surface treatments at laboratory levels and have shown promise to be used on actual components.

  1. Removal of pharmaceuticals from wastewater by biological processes, hydrodynamic cavitation and UV treatment.

    PubMed

    Zupanc, Mojca; Kosjek, Tina; Petkovšek, Martin; Dular, Matevž; Kompare, Boris; Širok, Brane; Blažeka, Željko; Heath, Ester

    2013-07-01

    To augment the removal of pharmaceuticals different conventional and alternative wastewater treatment processes and their combinations were investigated. We tested the efficiency of (1) two distinct laboratory scale biological processes: suspended activated sludge and attached-growth biomass, (2) a combined hydrodynamic cavitation-hydrogen peroxide process and (3) UV treatment. Five pharmaceuticals were chosen including ibuprofen, naproxen, ketoprofen, carbamazepine and diclofenac, and an active metabolite of the lipid regulating agent clofibric acid. Biological treatment efficiency was evaluated using lab-scale suspended activated sludge and moving bed biofilm flow-through reactors, which were operated under identical conditions in respect to hydraulic retention time, working volume, concentration of added pharmaceuticals and synthetic wastewater composition. The suspended activated sludge process showed poor and inconsistent removal of clofibric acid, carbamazepine and diclofenac, while ibuprofen, naproxen and ketoprofen yielded over 74% removal. Moving bed biofilm reactors were filled with two different types of carriers i.e. Kaldnes K1 and Mutag BioChip™ and resulted in higher removal efficiencies for ibuprofen and diclofenac. Augmentation and consistency in the removal of diclofenac were observed in reactors using Mutag BioChip™ carriers (85%±10%) compared to reactors using Kaldnes carriers and suspended activated sludge (74%±22% and 48%±19%, respectively). To enhance the removal of pharmaceuticals hydrodynamic cavitation with hydrogen peroxide process was evaluated and optimal conditions for removal were established regarding the duration of cavitation, amount of added hydrogen peroxide and initial pressure, all of which influence the efficiency of the process. Optimal parameters resulted in removal efficiencies between 3-70%. Coupling the attached-growth biomass biological treatment, hydrodynamic cavitation/hydrogen peroxide process and UV treatment resulted in removal efficiencies of >90% for clofibric acid and >98% for carbamazepine and diclofenac, while the remaining compounds were reduced to levels below the LOD. For ibuprofen, naproxen, ketoprofen and diclofenac the highest contribution to overall removal was attributed to biological treatment, for clofibric acid UV treatment was the most efficient, while for carbamazepine hydrodynamic cavitation/hydrogen peroxide process and UV treatment were equally efficient. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. Ray-based acoustic localization of cavitation in a highly reverberant environment.

    PubMed

    Chang, Natasha A; Dowling, David R

    2009-05-01

    Acoustic detection and localization of cavitation have inherent advantages over optical techniques because cavitation bubbles are natural sound sources, and acoustic transduction of cavitation sounds does not require optical access to the region of cavitating flow. In particular, near cavitation inception, cavitation bubbles may be visually small and occur infrequently, but may still emit audible sound pulses. In this investigation, direct-path acoustic recordings of cavitation events are made with 16 hydrophones mounted on the periphery of a water tunnel test section containing a low-cavitation-event-rate vortical flow. These recordings are used to localize the events in three dimensions via cross correlations to obtain arrival time differences. Here, bubble localization is hindered by reverberation, background noise, and the fact that both the pulse emission time and waveform are unknown. These hindrances are partially mitigated by a signal-processing scheme that incorporates straight-ray acoustic propagation and Monte-Carlo techniques for compensating ray-path, sound-speed, and hydrophone-location uncertainties. The acoustic localization results are compared to simultaneous optical localization results from dual-camera high-speed digital-video recordings. For 53 bubbles and a peak-signal to noise ratio frequency of 6.7 kHz, the root-mean-square spatial difference between optical and acoustic bubble location results was 1.94 cm. Parametric dependences in acoustic localization performance are also presented.

  3. Experimental investigation on cavitating flow shedding over an axisymmetric blunt body

    NASA Astrophysics Data System (ADS)

    Hu, Changli; Wang, Guoyu; Huang, Biao

    2015-03-01

    Nowadays, most researchers focus on the cavity shedding mechanisms of unsteady cavitating flows over different objects, such as 2D/3D hydrofoils, venturi-type section, axisymmetric bodies with different headforms, and so on. But few of them pay attention to the differences of cavity shedding modality under different cavitation numbers in unsteady cavitating flows over the same object. In the present study, two kinds of shedding patterns are investigated experimentally. A high speed camera system is used to observe the cavitating flows over an axisymmetric blunt body and the velocity fields are measured by a particle image velocimetry (PIV) technique in a water tunnel for different cavitation conditions. The U-type cavitating vortex shedding is observed in unsteady cavitating flows. When the cavitation number is 0.7, there is a large scale cavity rolling up and shedding, which cause the instability and dramatic fluctuation of the flows, while at cavitation number of 0.6, the detached cavities can be conjunct with the attached part to induce the break-off behavior again at the tail of the attached cavity, as a result, the final shedding is in the form of small scale cavity and keeps a relatively steady flow field. It is also found that the interaction between the re-entrant flow and the attached cavity plays an important role in the unsteady cavity shedding modality. When the attached cavity scale is insufficient to overcome the re-entrant flow, it deserves the large cavity rolling up and shedding just as that at cavitation number of 0.7. Otherwise, the re-entrant flow is defeated by large enough cavity to induce the cavity-combined process and small scale cavity vortexes shedding just as that of the cavitation number of 0.6. This research shows the details of two different cavity shedding modalities which is worthful and meaningful for the further study of unsteady cavitation.

  4. Cavitation controlled acoustic probe for fabric spot cleaning and moisture monitoring

    DOEpatents

    Sheen, Shuh-Haw; Chien, Hual-Te; Raptis, Apostolos C.

    1997-01-01

    A method and apparatus are provided for monitoring a fabric. An acoustic probe generates acoustic waves relative to the fabric. An acoustic sensor, such as an accelerometer is coupled to the acoustic probe for generating a signal representative of cavitation activity in the fabric. The generated cavitation activity representative signal is processed to indicate moisture content of the fabric. A feature of the invention is a feedback control signal is generated responsive to the generated cavitation activity representative signal. The feedback control signal can be used to control the energy level of the generated acoustic waves and to control the application of a cleaning solution to the fabric.

  5. Cavitation erosion mechanism of titanium alloy radiation rods in aluminum melt.

    PubMed

    Dong, Fang; Li, Xiaoqian; Zhang, Lihua; Ma, Liyong; Li, Ruiqing

    2016-07-01

    Ultrasound radiation rods play a key role in introducing ultrasonic to the grain refinement of large-size cast aluminum ingots (with diameter over 800 mm), but the severe cavitation corrosion of radiation rods limit the wide application of ultrasonic in the metallurgy field. In this paper, the cavitation erosion of Ti alloy radiation rod (TARR) in the semi-continuous direct-chill casting of 7050 Al alloy was investigated using a 20 kHz ultrasonic vibrator. The macro/micro characterization of Ti alloy was performed using an optical digital microscopy and a scanning electron microscopy, respectively. The results indicated that the cavitation erosion and the chemical reaction play different roles throughout different corrosion periods. Meanwhile, the relationship between mass-loss and time during cavitation erosion was measured and analyzed. According to the rate of mass-loss to time, the whole cavitation erosion process was divided into four individual periods and the mechanism in each period was studied accordingly. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Improvement of the cavitation erosion resistance for Cr3Si film on stainless steel by double cathode glow discharge

    NASA Astrophysics Data System (ADS)

    Ding, Hongqin; Qiu, Yujiang

    2017-04-01

    In this study, sputter-deposited Cr3Si film was prepared by double cathode glow discharge (DCGD) technique onto 304 stainless steel. The phase constituents, surface microstructure and chemical compositions of the film were examined by using X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). After the DCGD process, the hardness of Cr3Si film was 26 GPa, about 10 times of the stainless steel, 2.5 GPa. The cavitation erosion resistance of Cr3Si film and stainless steel were investigated by using an ultrasonic vibration cavitation erosion system. After 30 hours of cavitation tests, the cumulative mass loss of Cr3Si film was only 60% of the stainless steel. Compared with the untreated stainless steel, the cavitation erosion resistance of Cr3Si film was improved. The cavitation mechanism of Cr3Si film is due to the delamination and spalling of local surface layer derived from its inherent brittleness.

  7. Correlating Inertial Acoustic Cavitation Emissions with Material Erosion Resistance

    NASA Astrophysics Data System (ADS)

    Ibanez, I.; Hodnett, M.; Zeqiri, B.; Frota, M. N.

    The standard ASTM G32-10 concerns the hydrodynamic cavitation erosion resistance of materials by subjecting them to acoustic cavitation generated by a sonotrode. The work reported extends this technique by detecting and monitoring the ultrasonic cavitation, considered responsible for the erosion process, specifically for coupons of aluminium-bronze alloy. The study uses a 65 mm diameter variant of NPL's cavitation sensor, which detects broadband acoustic emissions, and logs acoustic signals generated in the MHz frequency range, using NPL's Cavimeter. Cavitation readings were made throughout the exposure duration, which was carried out at discrete intervals (900 to 3600 s), allowing periodic mass measurements to be made to assess erosion loss under a strict protocol. Cavitation measurements and erosion were compared for different separations of the sonotrode tip from the material under test. The maximum variation associated with measurement of cavitation level was between 2.2% and 3.3% when the separation (λ) between the transducer horn and the specimen increased from 0.5 to 1.0 mm, for a transducer (sonotrode) displacement amplitude of 43.5 μm. Experiments conducted at the same transducer displacement amplitude show that the mass loss of the specimen -a measure of erosion- was 67.0 mg (λ = 0.5 mm) and 66.0 mg (λ = 1.0 mm).

  8. On the flow structure of cloud cavitating flow around an axisymmetric body near the free surface

    NASA Astrophysics Data System (ADS)

    Wang, Yiwei; Wu, Xiaocui; Huang, Chenguang; Yu, XianXian

    2015-12-01

    The influence of the free surface on the cavitating flow is an important issue involved in the design of high speed surface vehicles. In the present paper, unsteady cavitating turbulent flow around an axisymmetric body near the free surface was investigated by both launching experiment and LES simulation. The vortex motion induced by cavity shedding under the effect of the free surface is emphatically analyzed by comparing with the submerged condition. The vortex shedding process around the projectile is not synchronized, while the asymmetric characteristic in collapse process is more remarkable, with the generation of multiple vortex ring structures.

  9. Detection of cavitation in hydraulic turbines

    NASA Astrophysics Data System (ADS)

    Escaler, Xavier; Egusquiza, Eduard; Farhat, Mohamed; Avellan, François; Coussirat, Miguel

    2006-05-01

    An experimental investigation has been carried out in order to evaluate the detection of cavitation in actual hydraulic turbines. The methodology is based on the analysis of structural vibrations, acoustic emissions and hydrodynamic pressures measured in the machine. The proposed techniques have been checked in real prototypes suffering from different types of cavitation. In particular, one Kaplan, two Francis and one Pump-Turbine have been investigated in the field. Additionally, one Francis located in a laboratory has also been tested. First, a brief description of the general features of cavitation phenomenon is given as well as of the main types of cavitation occurring in hydraulic turbines. The work presented here is focused on the most important ones which are the leading edge cavitation due to its erosive power, the bubble cavitation because it affects the machine performance and the draft tube swirl that limits the operation stability. Cavitation detection is based on the previous understanding of the cavity dynamics and its location inside the machine. This knowledge has been gained from flow visualisations and measurements in laboratory devices such as a high-speed cavitation tunnel and a reduced scale turbine test rig. The main techniques are the study of the high frequency spectral content of the signals and of their amplitude demodulation for a given frequency band. Moreover, low frequency spectral content can also be used in certain cases. The results obtained for the various types of cavitation found in the selected machines are presented and discussed in detail in the paper. Conclusions are drawn about the best sensor, measuring location, signal processing and analysis for each type of cavitation, which serve to validate and to improve the detection techniques.

  10. Diagnosing non-cavitated lesions in epidemiological studies: practical and scientific considerations.

    PubMed

    Carvalho, Joana Christina; Mestrinho, Heliana Dantas

    2014-01-01

    Over the last decade, there has been growing interest in diagnosing non-cavitated lesions in epidemiological studies involving large numbers of preschool children, schoolchildren and young adults. In this context, assessment of lesions characteristics indicating whether or not there is ongoing mineral loss is also considered relevant. The reasoning sustained by these studies is that diagnosis of the caries process limited to the cavitated level is no longer in accordance with current state-of-the-art knowledge in cariology. This paper highlights one topic of the lecture entitled "Caries Process: Evolving Evidence and Understanding," presented at the 18th Congress of the Brazilian Association for Oral Health Promotion (Associação Brasileira de Odontologia de Promoção de Saúde - ABOPREV) in April 2013. In the framework of epidemiological studies, the interest in diagnosing active and inactive non-cavitated lesions was elucidated. However, relevant questions associated with the diagnosis of non-cavitated lesions that might raise concerns among researchers and health administrators were not addressed. The present paper aims to bring these questions into discussion. The contribution of this discussion in terms of developing the understanding of caries decline is analyzed by using data from a caries trends study of Brazilian preschool children residing in the Federal District of Brazil as an example. The inclusion of active and inactive non-cavitated lesions in the diagnosis of the caries process allowed us to demonstrate that, in Brazilian 1- to 5-year-old children, caries prevalence decreased significantly from 1996 to 2006, simultaneously with a reduction in the rate of caries progression.

  11. Homogenization-assisted cavitation hybrid rotation extraction and macroporous resin enrichment of dihydroquercetin from Larix gmelinii.

    PubMed

    Xia, Yu; Wang, Yinhang; Li, Wei; Ma, Chunhui; Liu, Shouxin

    2017-12-01

    Cavitation hybrid rotation, which was and is still looked upon as an unavoidable nuisance in the flow systems, for extraction processing intensification of active chemical compounds from natural products. In this study, a homogenization-assisted cavitation hybrid rotation extraction method was applied to extract dihydroquercetin (DHQ) from larch (Larix gmelinii) wood root. The extraction parameters were optimized in single factor experiments with the DHQ extraction yields as the response values. The optimum conditions were as follows: number of extractions, three; ethanol volume fraction for the extraction, 60%; liquid-solid ratio for homogenization, 10mL/g; homogenization time, 8min; liquid-solid ratio for cavitation extraction, 9mL/g, and cavitation extraction time, 35min. Under these conditions, the DHQ content in extract was 4.50±0.02mg/g, and the extraction efficiency was higher than those of traditional techniques. Cavitation can be effectively used to improve the extraction rate by increasing the mass transfer rates and possible rupture of cell wall due to formation of microcavities leading to higher product yields with reduced processing time and solvent consumption. After the extraction process, macroporous resin column chromatography was used to concentrate and purify the DHQ. Three resins were selected from fifteen macroporous resins for further investigation of their performance. Among these resins, AB-8 resin exhibited relatively better adsorption capacities and desorption ratios for DHQ. The ethanol volume fraction of the solutions for sample loading and desorption, and flow rates for loading and desorption were optimized for the macroporous resin column chromatography. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Investigation of nozzle flow and cavitation characteristics in a diesel injector.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Som, S.; Ramirez, A.; Aggarwal, S.

    2010-04-01

    Cavitation and turbulence inside a diesel injector play a critical role in primary spray breakup and development processes. The study of cavitation in realistic injectors is challenging, both theoretically and experimentally, since the associated two-phase flow field is turbulent and highly complex, characterized by large pressure gradients and small orifice geometries. We report herein a computational investigation of the internal nozzle flow and cavitation characteristics in a diesel injector. A mixture based model in FLUENT V6.2 software is employed for simulations. In addition, a new criterion for cavitation inception based on the total stress is implemented, and its effectiveness inmore » predicting cavitation is evaluated. Results indicate that under realistic diesel engine conditions, cavitation patterns inside the orifice are influenced by the new cavitation criterion. Simulations are validated using the available two-phase nozzle flow data and the rate of injection measurements at various injection pressures (800-1600 bar) from the present study. The computational model is then used to characterize the effects of important injector parameters on the internal nozzle flow and cavitation behavior, as well as on flow properties at the nozzle exit. The parameters include injection pressure, needle lift position, and fuel type. The propensity of cavitation for different on-fleet diesel fuels is compared with that for n-dodecane, a diesel fuel surrogate. Results indicate that the cavitation characteristics of n-dodecane are significantly different from those of the other three fuels investigated. The effect of needle movement on cavitation is investigated by performing simulations at different needle lift positions. Cavitation patterns are seen to shift dramatically as the needle lift position is changed during an injection event. The region of significant cavitation shifts from top of the orifice to bottom of the orifice as the needle position is changed from fully open (0.275 mm) to nearly closed (0.1 mm), and this behavior can be attributed to the effect of needle position on flow patterns upstream of the orifice. The results demonstrate the capability of the cavitation model to predict cavitating nozzle flows in realistic diesel injectors and provide boundary conditions, in terms of vapor fraction, velocity, and turbulence parameters at the nozzle exit, which can be coupled with the primary breakup simulation.« less

  13. Numerical estimation of cavitation intensity

    NASA Astrophysics Data System (ADS)

    Krumenacker, L.; Fortes-Patella, R.; Archer, A.

    2014-03-01

    Cavitation may appear in turbomachinery and in hydraulic orifices, venturis or valves, leading to performance losses, vibrations and material erosion. This study propose a new method to predict the cavitation intensity of the flow, based on a post-processing of unsteady CFD calculations. The paper presents the analyses of cavitating structures' evolution at two different scales: • A macroscopic one in which the growth of cavitating structures is calculated using an URANS software based on a homogeneous model. Simulations of cavitating flows are computed using a barotropic law considering presence of air and interfacial tension, and Reboud's correction on the turbulence model. • Then a small one where a Rayleigh-Plesset software calculates the acoustic energy generated by the implosion of the vapor/gas bubbles with input parameters from macroscopic scale. The volume damage rate of the material during incubation time is supposed to be a part of the cumulated acoustic energy received by the solid wall. The proposed analysis method is applied to calculations on hydrofoil and orifice geometries. Comparisons between model results and experimental works concerning flow characteristic (size of cavity, pressure,velocity) as well as pitting (erosion area, relative cavitation intensity) are presented.

  14. Bubble dynamics in viscoelastic soft tissue in high-intensity focal ultrasound thermal therapy.

    PubMed

    Zilonova, E; Solovchuk, M; Sheu, T W H

    2018-01-01

    The present study is aimed to investigate bubble dynamics in a soft tissue, to which HIFU's continuous harmonic pulse is applied by introducing a viscoelastic cavitation model. After a comparison of some existing cavitation models, we decided to employ Gilmore-Akulichev model. This chosen cavitation model should be coupled with the Zener viscoelastic model in order to be able to simulate soft tissue features such as elasticity and relaxation time. The proposed Gilmore-Akulichev-Zener model was investigated for exploring cavitation dynamics. The parametric study led us to the conclusion that the elasticity and viscosity both damp bubble oscillations, whereas the relaxation effect depends mainly on the period of the ultrasound wave. The similar influence of elasticity, viscosity and relaxation time on the temperature inside the bubble can be observed. Cavitation heat source terms (corresponding to viscous damping and pressure wave radiated by bubble collapse) were obtained based on the proposed model to examine the cavitation significance during the treatment process. Their maximum values both overdominate the acoustic ultrasound term in HIFU applications. Elasticity was revealed to damp a certain amount of deposited heat for both cavitation terms. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Development of an Acoustic Localization Method for Cavitation Experiments in Reverberant Environments

    NASA Astrophysics Data System (ADS)

    Ranjeva, Minna; Thompson, Lee; Perlitz, Daniel; Bonness, William; Capone, Dean; Elbing, Brian

    2011-11-01

    Cavitation is a major concern for the US Navy since it can cause ship damage and produce unwanted noise. The ability to precisely locate cavitation onset in laboratory scale experiments is essential for proper design that will minimize this undesired phenomenon. Measuring the cavitation onset is more accurately determined acoustically than visually. However, if other parts of the model begin to cavitate prior to the component of interest the acoustic data is contaminated with spurious noise. Consequently, cavitation onset is widely determined by optically locating the event of interest. The current research effort aims at developing an acoustic localization scheme for reverberant environments such as water tunnels. Currently cavitation bubbles are being induced in a static water tank with a laser, allowing the localization techniques to be refined with the bubble at a known location. The source is located with the use of acoustic data collected with hydrophones and analyzed using signal processing techniques. To verify the accuracy of the acoustic scheme, the events are simultaneously monitored visually with the use of a high speed camera. Once refined testing will be conducted in a water tunnel. This research was sponsored by the Naval Engineering Education Center (NEEC).

  16. Passive acoustic mapping of magnetic microbubbles for cavitation enhancement and localization.

    PubMed

    Crake, Calum; Victor, Marie de Saint; Owen, Joshua; Coviello, Christian; Collin, Jamie; Coussios, Constantin-C; Stride, Eleanor

    2015-01-21

    Magnetic targeting of microbubbles functionalized with superparamagnetic nanoparticles has been demonstrated previously for diagnostic (B-mode) ultrasound imaging and shown to enhance gene delivery in vitro and in vivo. In the present work, passive acoustic mapping (PAM) was used to investigate the potential of magnetic microbubbles for localizing and enhancing cavitation activity under focused ultrasound. Suspensions of magnetic microbubbles consisting of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), air and 10 nm diameter iron oxide nanoparticles were injected into a tissue mimicking phantom at different flow velocities (from 0 to 50 mm s(-1)) with or without an applied magnetic field. Microbubbles were excited using a 500 kHz single element focused transducer at peak negative focal pressures of 0.1-1.0 MPa, while a 64 channel imaging array passively recorded their acoustic emissions. Magnetic localization of microbubble-induced cavitation activity was successfully achieved and could be resolved using PAM as a shift in the spatial distribution and increases in the intensity and sustainability of cavitation activity under the influence of a magnetic field. Under flow conditions at shear rates of up to 100 s(-1) targeting efficacy was maintained. Application of a magnetic field was shown to consistently increase the energy of cavitation emissions by a factor of 2-5 times over the duration of exposures compared to the case without targeting, which was approximately equivalent to doubling the injected microbubble dose. These results suggest that magnetic targeting could be used to localize and increase the concentration of microbubbles and hence cavitation activity for a given systemic dose of microbubbles or ultrasound intensity.

  17. Hydrodynamic cavitation: characterization of a novel design with energy considerations for the inactivation of Saccharomyces cerevisiae in apple juice.

    PubMed

    Milly, P J; Toledo, R T; Kerr, W L; Armstead, D

    2008-08-01

    A Shockwave Power Reactor consisting of an annulus with a rotating pock-marked inner cylinder was used to induce hydrodynamic cavitation in calcium-fortified apple juice flowing in the annular space. Lethality on Saccharomyces cerevisiae was assessed at processing temperatures of 65 and 76.7 degrees C. Details of the novel equipment design were presented and energy consumption was compared to conventional and pulsed electric fields processing technologies. The mean log cycle reduction of S. cerevisiae was 6.27 CFU/mL and all treatments resulted in nonrecoverable viable cells. Induced lethality from hydrodynamic cavitation on S. cerevisiae exceeded the predicted values based on experimentally determined thermal resistance. Rotation of 3000 and 3600 rpm at flow rates greater than 1.0 L/min raised product temperature from 20 to 65.6 or 76.7 degrees C, respectively, and energy input was less than 220 kJ/kg. Conversion efficiency from electrical to thermal was 55% to 84%. Hydrodynamic cavitation enhanced lethality of spoilage microorganisms in minimally processed juices and reduced energy usage.

  18. Effect of ultrasonic cavitation on the diffusivity of a point defect in the passive film on formed Nb in 0.5 M HCl solution.

    PubMed

    Li, D G

    2015-11-01

    This work primarily focused on the influence of ultrasonic cavitation on the transport property of the point defect in the passive film on formed Nb in 0.5M HCl solution via electrochemical techniques based on the point defect model (PDM). The influence of ultrasonic cavitation on the composition and structure of the passive film was detected by X-ray photoelectron spectroscopy (XPS) and Auger electron spectroscopy (AES). The transport property of a point defect in the passive film was characterized by the diffusivity of the point defect (D0). The influences of the ultrasonic cavitation power, passivated time and the distance between horn bottom and sample surface on D0 were analyzed. The results demonstrated that the passive film formed on Nb was an n-type semiconductor with a donor density (ND) ranging from 10(19) cm(-3) to 10(20) cm(-3) in the case of static state, while the order of ND increased one to two times by applying ultrasonic cavitation during film formation. The diffusivity of the point defect (D0) in the passive film formed on Nb at 0.5 V for 1 h in a 0.5 M HCl solution in the static state was calculated to be 9.704×10(-18) cm(2) s(-1), and it increased to 1.255×10(-16) cm(2) s(-1), 7.259×10(-16) cm(2) s(-1) and 7.296×10(-15) cm(2) s(-1) when applying the 180 W, 270 W and 450 W ultrasonic cavitation powers during film formation. D0 increased with the increment of the ultrasonic cavitation power, and decreased with the increased in formation time and distance between the horn bottom and sample surface. AES results showed the film structure and composition were changed by applying the ultrasonic cavitation. XPS results revealed that the passive film was mainly composed of Nb2O5 in the static state, and the low valence Nb-oxide (NbO) appeared in the passive film except Nb2O5 in the case of applying a 270 W ultrasonic cavitation power. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Developing a CD-CBM Anticipatory Approach for Cavitation - Defining a Model-Based Descriptor Consistent Across Processes, Phase 1 Final Report Context-Dependent Prognostics and Health Assessment: A New Paradigm for Condition-based Maintenance SBIR Topic No. N98-114

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allgood, G.O.; Dress, W.B.; Kercel, S.W.

    1999-06-01

    The objective of this research, and subsequent testing, was to identify specific features of cavitation that could be used as a model-based descriptor in a context-dependent condition-based maintenance (CD-CBM) anticipatory prognostic and health assessment model. This descriptor is based on the physics of the phenomena, capturing the salient features of the process dynamics. The test methodology and approach were developed to make the cavitation features the dominant effect in the process and collected signatures. This would allow the accurate characterization of the salient cavitation features at different operational states. By developing such an abstraction, these attributes can be used asmore » a general diagnostic for a system or any of its components. In this study, the particular focus will be pumps. As many as 90% of pump failures are catastrophic. They seem to be operating normally and fail abruptly without warning. This is true whether the failure is sudden hardware damage requiring repair, such as a gasket failure, or a transition into an undesired operating mode, such as cavitation. This means that conventional diagnostic methods fail to predict 90% of incipient failures and that in addressing this problem, model-based methods can add value where it is actually needed.« less

  20. Investigation of the properties of laser-induced cavitation bubble collapse and sound waves

    NASA Astrophysics Data System (ADS)

    Li, Shengyong; Ai, Xiaochuan; Wu, Ronghua; Cao, Jing

    2017-02-01

    The theoretical model of single bubble movement in an ideal solution, to carry on the numerical simulation of the process of cavitation in the liquid, the liquid in different laser energy, laser induced cavitation rules and acoustic characteristics were studied by high-speed camera, high frequency measurements of the hydrophone. The results show that with the increase of laser energy, the period of bubble pulsation and the maximum bubble radius increase gradually, and the amplitude of the laser acoustic signal becomes larger.

  1. Universal approach to analysis of cavitation and liquid-impingement erosion data

    NASA Technical Reports Server (NTRS)

    Rao, P. V.; Young, S. G.

    1982-01-01

    Cavitation erosion experimental data was analyzed by using normalization and curve-fitting techniques. Data were taken from experiments on several materials tested in both a rotating disk device and a magnetostriction apparatus. Cumulative average volume loss rate and time data were normalized relative to the peak erosion rate and the time to peak erosion rate, respectively. From this process a universal approach was derived that can include data on specific materials from different test devices for liquid impingement and cavitation erosion studies.

  2. Combined slurry and cavitation erosion resistance of surface modified SS410 stainless steel

    NASA Astrophysics Data System (ADS)

    Amarendra, H. J.; Pratap, M. S.; Karthik, S.; Punitha Kumara, M. S.; Rajath, H. C.; Ranjith, H.; Shubhatunga, S. V.

    2018-03-01

    Slurry erosion and combined slurry and cavitation erosion resistance of thermal spray coatings are studied and compared with the as-received martensitic stainless steel material. 70Ni-Cr coatings are deposited on SS 410 material through plasma thermal spray process. The synergy effect of the combined slurry and cavitation erosion resistance of plasma thermal spray coatings were investigated in a slurry pot tester in the presence of bluff bodies known as Cavitation Inducers. Results showed the combined slurry and cavitation erosion resistance of martensitic stainless steel - 410 can be improved by plasma thermal spray coating. It is observed that the plasma spray coated specimens are better erosion resistant than the as- received material, subjected to erosion test under similar conditions. As-received and the surface modified steels are mechanically characterized for its hardness, bending. Morphological studies are conducted through scanning electron microscope.

  3. Application of hydrodynamic cavitation to improve the biodegradability of mature landfill leachate.

    PubMed

    Bis, M; Montusiewicz, A; Ozonek, J; Pasieczna-Patkowska, S

    2015-09-01

    In this study, the application of hydrodynamic cavitation to improve the biodegradability of mature landfill leachate was investigated. Three configurations of cavitation device were examined and operational parameters of the process were selected. The study indicated that the orifice plate with a 3/10mm diameter conical concentric hole, characterized by the cavitation number of 0.033, is a reasonable choice to ensure the enhanced biodegradability of mature leachate. Using such a configuration and maintaining 30 recirculation passes through the cavitation zone at inlet pressure of 7 bar, the highest increase of biodegradability index (BI) of approximately 22% occurred, i.e., from the value of 0.046 to 0.056. The FT-IR/PAS analysis confirmed a degradation of refractory compounds that typically prevail in mature leachate. An evaluation of energy efficiency was made in terms of the actual consumed energy measured by using the Kyoritsu KEW6310 Power Quality Tester. A cavitational yield of 9.8 mg COD kJ(-1) was obtained for the optimum configuration and 30 recirculation passes. Regarding energy efficiency, the application of 10 cavitation cycles appeared to be the most profitable. This was due to an almost threefold higher cavitational yield of 27.5 mg COD kJ(-1). However, the preferable option should be selected by considering a satisfactory effect in the biodegradability enhancement. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Scale effects on propeller cavitating hydrodynamic and hydroacoustic performances with non-uniform inflow

    NASA Astrophysics Data System (ADS)

    Yang, Qiongfang; Wang, Yongsheng; Zhang, Zhihong

    2013-03-01

    Considering the lack of theoretical models and ingredients necessary to explain the scaling of the results of propeller cavitation inception and cavitating hydroacoustics from model tests to full scale currently, and the insufficient reflection of the nuclei effects on cavitation in the numerical methods, the cavitating hydrodynamics and cavitation low frequency noise spectrum of three geometrically similar 7-bladed highly skewed propellers with non-uniform inflow are addressed. In this process, a numerical bridge from the multiphase viscous simulation of propeller cavitation hydrodynamics to its hydro-acoustics is built, and the scale effects on performances and the applicability of exist scaling law are analyzed. The effects of non-condensable gas(NCG) on cavitation inception are involved explicitly in the improved Sauer's cavitation model, and the cavity volume acceleration related to its characteristic length is used to produce the noise spectrum. Results show that, with the same cavitation number, the cavity extension on propeller blades increases with diameter associated with an earlier shift of the beginning point of thrust decline induced by cavitation, while the three decline slopes of thrust breakdown curves are found to be nearly the same. The power of the scaling law based on local Reynolds number around 0.9 R section is determined as 0.11. As for the smallest propeller, the predominant tonal noise is located at blade passing frequency(BPF), whereas 2BPF for the middle and both 2BPF and 3BPF for the largest, which shows the cavitating line spectrum is fully related to the interaction between non-uniform inflow and fluctuated cavity volume. The predicted spectrum level exceedance from the middle to the large propeller is 6.65 dB at BPF and 5.94 dB at 2BPF. Since it just differs less than 2 dB to the increment obtained by empirical scaling law, it is inferred that the scale effects on them are acceptable with a sufficient model scale, and so do the scaling law. The numerical implementation of cavitating hydrodynamics and hydro-acoustics prediction of propeller in big scale in wake has been completed.

  5. In situ observation of ultrasonic cavitation-induced fragmentation of the primary crystals formed in Al alloys.

    PubMed

    Wang, Feng; Tzanakis, Iakovos; Eskin, Dmitry; Mi, Jiawei; Connolley, Thomas

    2017-11-01

    The cavitation-induced fragmentation of primary crystals formed in Al alloys were investigated for the first time by high-speed imaging using a novel experimental approach. Three representative primary crystal types, Al 3 Ti, Si and Al 3 V with different morphologies and mechanical properties were first extracted by deep etching of the corresponding Al alloys and then subjected to ultrasonic cavitation processing in distilled water. The dynamic interaction between the cavitation bubbles and primary crystals was imaged in situ and in real time. Based on the recorded image sequences, the fragmentation mechanisms of primary crystals were studied. It was found that there are three major mechanisms by which the primary crystals were fragmented by cavitation bubbles. The first one was a slow process via fatigue-type failure. A cyclic pressure exerted by stationary pulsating bubbles caused the propagation of a crack pre-existing in the primary crystal to a critical length which led to fragmentation. The second mechanism was a sudden process due to the collapse of bubbles in a passing cavitation cloud. The pressure produced upon the collapse of the cloud promoted rapid monotonic crack growth and fast fracture in the primary crystals. The third observed mechanism was normal bending fracture as a result of the high pressure arising from the collapse of a bubble cloud and the crack formation at the branch connection points of dendritic primary crystals. The fragmentation of dendrite branches due to the interaction between two freely moving dendritic primary crystals was also observed. A simplified fracture analysis of the observed phenomena was performed. The specific fragmentation mechanism for the primary crystals depended on their morphology and mechanical properties. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  6. Degradation of organic wastewater by hydrodynamic cavitation combined with acoustic cavitation.

    PubMed

    Yi, Chunhai; Lu, Qianqian; Wang, Yun; Wang, Yixuan; Yang, Bolun

    2018-05-01

    In this paper, the decomposition of Rhodamine B (RhB) by hydrodynamic cavitation (HC), acoustic cavitation (AC) and the combination of these individual methods (HAC) have been investigated. The degradation of 20 L RhB aqueous solution was carried out in a self-designed HAC reactor, where hydrodynamic cavitation and acoustic cavitation could take place in the same space simultaneously. The effects of initial concentration, inlet pressure, solution temperature and ultrasonic power were studied and discussed. Obvious synergies were found in the HAC process. The combined method achieved the best conversion, and the synergistic effect in HAC was even up to 119% with the ultrasonic power of 220 W in a treatment time of 30 min. The time-independent synergistic factor based on rate constant was introduced and the maximum value reached 40% in the HAC system. Besides, the hybrid HAC method showed great superiority in energy efficiency at lower ultrasonic power (88-176 W). Therefore, HAC technology can be visualized as a promising method for wastewater treatment with good scale-up possibilities. Copyright © 2018 Elsevier B.V. All rights reserved.

  7. Impact characteristics for high-pressure large-flow water-based emulsion pilot operated check valve reverse opening

    NASA Astrophysics Data System (ADS)

    Liu, Lei; Huang, Chuanhui; Yu, Ping; Zhang, Lei

    2017-10-01

    To improve the dynamic characteristics and cavitation characteristics of large-flow pilot operated check valve, consider the pilot poppet as the research object, analyses working principle and design three different kinds of pilot poppets. The vibration characteristics and impact characteristics are analyzed. The simulation model is established through flow field simulation software. The cavitation characteristics of large-flow pilot operated check valve are studied and discussed. On this basis, high-pressure large-flow impact experimental system is used for impact experiment, and the cavitation index is discussed. Then optimal structure is obtained. Simulation results indicate that the increase of pilot poppet half cone angle can effectively reduce the cavitation area, reducing the generation of cavitation. Experimental results show that the pressure impact is not decreasing with increasing of pilot poppet half cone angle in process of unloading, but the unloading capacity, response speed and pilot poppet half cone angle are positively correlated. The impact characteristics of 60° pilot poppet, and its cavitation index is lesser, which indicates 60° pilot poppet is the optimal structure, with the theory results are basically identical.

  8. Enhancement and Passive Acoustic Mapping of Cavitation from Fluorescently Tagged Magnetic Resonance-Visible Magnetic Microbubbles In Vivo.

    PubMed

    Crake, Calum; Owen, Joshua; Smart, Sean; Coviello, Christian; Coussios, Constantin-C; Carlisle, Robert; Stride, Eleanor

    2016-12-01

    Previous work has indicated the potential of magnetically functionalized microbubbles to localize and enhance cavitation activity under focused ultrasound exposure in vitro. The aim of this study was to investigate magnetic targeting of microbubbles for promotion of cavitation in vivo. Fluorescently labelled magnetic microbubbles were administered intravenously in a murine xenograft model. Cavitation was induced using a 0.5-MHz focused ultrasound transducer at peak negative focal pressures of 1.2-2.0 MPa and monitored in real-time using B-mode imaging and passive acoustic mapping. Magnetic targeting was found to increase the amplitude of the cavitation signal by approximately 50% compared with untargeted bubbles. Post-exposure magnetic resonance imaging indicated deposition of magnetic nanoparticles in tumours. Magnetic targeting was similarly associated with increased fluorescence intensity in the tumours after the experiments. These results suggest that magnetic targeting could potentially be used to improve delivery of cavitation-mediated therapy and that passive acoustic mapping could be used for real-time monitoring of this process. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Numerical Investigation of a Cavitating Mixing Layer of Liquefied Natural Gas (LNG) Behind a Flat Plate Splitter

    NASA Astrophysics Data System (ADS)

    Rahbarimanesh, Saeed; Brinkerhoff, Joshua

    2017-11-01

    The mutual interaction of shear layer instabilities and phase change in a two-dimensional cryogenic cavitating mixing layer is investigated using a numerical model. The developed model employs the homogeneous equilibrium mixture (HEM) approach in a density-based framework to compute the temperature-dependent cavitation field for liquefied natural gas (LNG). Thermal and baroclinic effects are captured via iterative coupled solution of the governing equations with dynamic thermophysical models that accurately capture the properties of LNG. The mixing layer is simulated for vorticity-thickness Reynolds numbers of 44 to 215 and cavitation numbers of 0.1 to 1.1. Attached cavity structures develop on the splitter plate followed by roll-up of the separated shear layer via the well-known Kelvin-Helmholtz mode, leading to streamwise accumulation of vorticity and eventual shedding of discrete vortices. Cavitation occurs as vapor cavities nucleate and grow from the low-pressure cores in the rolled-up vortices. Thermal effects and baroclinic vorticity production are found to have significant impacts on the mixing layer instability and cavitation processes.

  10. Relating xylem cavitation to gas exchange in cotton

    USDA-ARS?s Scientific Manuscript database

    Acoustic emissions (AEs) from xylem cavitation events are characteristic of transpiration processes. Though a body of work using AE exists with a large number of species, cotton and other agronomically important crops have either not been investigated, or limited information exists. The objective of...

  11. Relating xylem cavitation to transpiration in cotton

    USDA-ARS?s Scientific Manuscript database

    Acoustic emmisions (AEs) from xylem cavitation events are characteristic of transpiration processes. Even though a body of work employing AE exists with a large number of species, cotton and other agronomically important crops have either not been investigated, or limited information exists. A few s...

  12. CAVITATION SOUNDS DURING CERVICOTHORACIC SPINAL MANIPULATION.

    PubMed

    Dunning, James; Mourad, Firas; Zingoni, Andrea; Iorio, Raffaele; Perreault, Thomas; Zacharko, Noah; de Las Peñas, César Fernández; Butts, Raymond; Cleland, Joshua A

    2017-08-01

    No study has previously investigated the side, duration or number of audible cavitation sounds during high-velocity low-amplitude (HVLA) thrust manipulation to the cervicothoracic spine. The primary purpose was to determine which side of the spine cavitates during cervicothoracic junction (CTJ) HVLA thrust manipulation. Secondary aims were to calculate the average number of cavitations, the duration of cervicothoracic thrust manipulation, and the duration of a single cavitation. Quasi-experimental study. Thirty-two patients with upper trapezius myalgia received two cervicothoracic HVLA thrust manipulations targeting the right and left T1-2 articulation, respectively. Two high sampling rate accelerometers were secured bilaterally 25 mm lateral to midline of the T1-2 interspace. For each manipulation, two audio signals were extracted using Short-Time Fourier Transformation (STFT) and singularly processed via spectrogram calculation in order to evaluate the frequency content and number of instantaneous energy bursts of both signals over time for each side of the CTJ. Unilateral cavitation sounds were detected in 53 (91.4%) of 58 cervicothoracic HVLA thrust manipulations and bilateral cavitation sounds were detected in just five (8.6%) of the 58 thrust manipulations; that is, cavitation was significantly (p<0.001) more likely to occur unilaterally than bilaterally. In addition, cavitation was significantly (p<0.0001) more likely to occur on the side contralateral to the clinician's short-lever applicator. The mean number of audible cavitations per manipulation was 4.35 (95% CI 2.88, 5.76). The mean duration of a single manipulation was 60.77 ms (95% CI 28.25, 97.42) and the mean duration of a single audible cavitation was 4.13 ms (95% CI 0.82, 7.46). In addition to single-peak and multi-peak energy bursts, spectrogram analysis also demonstrated high frequency sounds, low frequency sounds, and sounds of multiple frequencies for all 58 manipulations. Cavitation was significantly more likely to occur unilaterally, and on the side contralateral to the short-lever applicator contact, during cervicothoracic HVLA thrust manipulation. Clinicians should expect multiple cavitation sounds when performing HVLA thrust manipulation to the CTJ. Due to the presence of multi-peak energy bursts and sounds of multiple frequencies, the cavitation hypothesis (i.e. intra-articular gas bubble collapse) alone appears unable to explain all of the audible sounds during HVLA thrust manipulation, and the possibility remains that several phenomena may be occurring simultaneously. 2b.

  13. The role of positive and negative pressure on cavitation nucleation in nanodroplet-mediated histotripsy.

    PubMed

    Vlaisavljevich, Eli; Aydin, Omer; Lin, Kuang-Wei; Durmaz, Yasemin Yuksel; Fowlkes, Brian; ElSayed, Mohamed; Xu, Zhen

    2016-01-21

    Nanodroplet-mediated histotripsy (NMH) is an ultrasound ablation technique combining histotripsy with acoustically sensitive perfluorocarbon (PFC) nanodroplets that can be selectively delivered to tumor cells for targeted tumor ablation. NMH takes advantage of the significantly reduced cavitation threshold of the nanodroplets, allowing for cavitation to be selectively generated only in regions containing nanodroplets. Understanding the physical mechanisms underlying the nanodroplet cavitation process is essential to the development of NMH. In this study, we hypothesize that cavitation nucleation is caused by the negative pressure (p-) exposed to the PFC, and the NMH cavitation threshold is therefore determined by the incident p-  of the single-cycle pulses commonly used in NMH. This paper reports the first study that separately investigates the effects of negative and positive pressure on the NMH cavitation threshold using near half-cycle ultrasound pulses with dominant negative (negative-polarity pulses) or positive (positive-polarity pulses) pressure phases. Tissue phantoms containing perfluorohexane (PFH) nanodroplets were exposed to negative-polarity and positive-polarity pulses generated by a frequency compounding transducer recently developed in our lab, and the probability of generating cavitation was measured as a function of peak negative (p-) and peak positive (p+) pressure. The results showed close agreement in the p- cavitation threshold for PFH phantoms exposed to negative-polarity (11.4 ± 0.1 MPa) and positive-polarity (11.7 ± 0.2 MPa) pulses. The p+ at the cavitation threshold, in contrast, was measured to be sign ficantly different for the negative-polarity (4.0 ± 0.1 MPa) and positive-polarity (42.6 ± 0.2 MPa) pulses. In the final part of this study, the experimental results were compared to the cavitation threshold predicted by classical nucleation theory (CNT), with results showing close agreement between simulations and experiments. Overall, the results support our hypothesis and provide significant insight into the physical mechanisms underlying NMH.

  14. AN EFFICIENT TREATMENT STRATEGY FOR HISTOTRIPSY BY REMOVING CAVITATION MEMORY

    PubMed Central

    Wang, Tzu-Yin; Xu, Zhen; Hall, Timothy L.; Fowlkes, J. Brian; Cain, Charles A.

    2012-01-01

    Cavitation memory effects occur when remnants of cavitation bubbles (nuclei) persist in the host medium and act as seeds for subsequent events. In pulsed cavitational ultrasound therapy, or histotripsy, this effect may cause cavitation to repeatedly occur at these seeded locations within a target volume, producing inhomogeneous tissue fractionation or requiring an excess number of pulses to completely homogenize the target volume. We hypothesized that by removing the cavitation memory, i.e., the persistent nuclei, the cavitation bubbles could be induced at random locations in response to each pulse; therefore, complete disruption of a tissue volume may be achieved with fewer pulses. To test the hypothesis, the cavitation memory was passively removed by increasing the intervals between successive pulses, Δt, from 2, 10, 20, 50 and 100, to 200 ms. Histotripsy treatments were performed in red blood cell tissue phantoms and ex vivo livers using 1-MHz ultrasound pulses of 10 cycles at P−/P+ pressure of 21/59 MPa. The phantom study allowed for direct visualization of the cavitation patterns and the lesion development process in real time using high-speed photography; the ex vivo tissue study provided validation of the memory effect in real tissues. Results of the phantom study showed an exponential decrease in the correlation coefficient between cavitation patterns in successive pulses from 0.5 ± 0.1 to 0.1 ± 0.1 as Δt increased from 2–200 ms; correspondingly, the lesion was completely fractionated with significantly fewer pulses for longer Δts. In the tissue study, given the same number of therapy pulses, complete and homogeneous tissue fractionation with well-defined lesion boundaries was achieved only for Δt ≥ 100 ms. These results indicated that the removal of the cavitation memory resulted in more efficient treatments and homogeneous lesions. PMID:22402025

  15. Effect of sonication on the colloidal stability of iron oxide nanoparticles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sodipo, Bashiru Kayode; Aziz, Azlan Abdul

    2015-04-24

    Colloidal stability of superparamagnetic iron oxide nanoparticles’ (SPION) suspensions, ultrasonically irradiated at various pH was studied. Electrophoresis measurement of the sonicated SPION showed that the shock waves and other unique conditions generated from the acoustic cavitation process (formation, growth and collapse of bubbles) affect the zeta potential value of the suspension. In this work, stabled colloidal suspensions of SPION were prepared and their pH is varied between 3 and 5. Prior to ultrasonic irradiation of the suspensions, their initial zeta potential values were determined. After ultrasonic irradiation of the suspensions, we observed that the sonication process interacts with colloidal stabilitymore » of the nanoparticles. The results demonstrated that only suspensions with pH less 4 were found stable and able to retain more than 90% of its initial zeta potential value. However, at pH greater than 4, the suspensions were found unstable. The result implies that good zeta potential value of SPION can be sustained in sonochemical process as long as the pH of the mixture is kept below 4.« less

  16. Mitigation of tip vortex cavitation by means of air injection on a Kaplan turbine scale model

    NASA Astrophysics Data System (ADS)

    Rivetti, A.; Angulo, M.; Lucino, C.; Liscia, S.

    2014-03-01

    Kaplan turbines operating at full-load conditions may undergo excessive vibration, noise and cavitation. In such cases, damage by erosion associated to tip vortex cavitation can be observed at the discharge ring. This phenomenon involves design features such as (1) overhang of guide vanes; (2) blade profile; (3) gap increasing size with blade opening; (4) suction head; (5) operation point; and (6) discharge ring stiffness, among others. Tip vortex cavitation may cause erosion at the discharge ring and draft tube inlet following a wavy pattern, in which the number of vanes can be clearly identified. Injection of pressurized air above the runner blade centerline was tested as a mean to mitigate discharge ring cavitation damage on a scale model. Air entrance was observed by means of a high-speed camera in order to track the air trajectory toward its mergence with the tip vortex cavitation core. Post-processing of acceleration signals shows that the level of vibration and the RSI frequency amplitude decrease proportionally with air flow rate injected. These findings reveal the potential mitigating effect of air injection in preventing cavitation damage and will be useful in further tests to be performed on prototype, aiming at determining the optimum air flow rate, size and distribution of the injectors.

  17. Spatial-temporal ultrasound imaging of residual cavitation bubbles around a fluid-tissue interface in histotripsy.

    PubMed

    Hu, Hong; Xu, Shanshan; Yuan, Yuan; Liu, Runna; Wang, Supin; Wan, Mingxi

    2015-05-01

    Cavitation is considered as the primary mechanism of soft tissue fragmentation (histotripsy) by pulsed high-intensity focused ultrasound. The residual cavitation bubbles have a dual influence on the histotripsy pulses: these serve as nuclei for easy generation of new cavitation, and act as strong scatterers causing energy "shadowing." To monitor the residual cavitation bubbles in histotripsy, an ultrafast active cavitation imaging method with relatively high signal-to-noise ratio and good spatial-temporal resolution was proposed in this paper, which combined plane wave transmission, minimum variance beamforming, and coherence factor weighting. The spatial-temporal evolutions of residual cavitation bubbles around a fluid-tissue interface in histotripsy under pulse duration (PD) of 10-40 μs and pulse repetition frequency (PRF) of 0.67-2 kHz were monitored by this method. The integrated bubble area curves inside the tissue interface were acquired from the bubble image sequence, and the formation process of histotripsy damage was estimated. It was observed that the histotripsy efficiency decreased with both longer PDs and higher PRFs. A direct relationship with a coefficient of 1.0365 between histotripsy lesion area and inner residual bubble area was found. These results can assist in monitoring and optimization of the histotripsy treatment further.

  18. The improvement of the surface hardness of stainless steel and aluminium alloy by ultrasonic cavitation peening

    NASA Astrophysics Data System (ADS)

    Janka, Styková; Miloš, Müller; Jan, Hujer

    This article presents first results of the experimental investigation of the influence of the cavitation shot less peening process on the properties of stainless steel and aluminium alloy specimens. The cavitation field was generated by an ultrasonic horn submerged in water and operated by an ultrasonic generator. The temperature of the water was controlled by thermometer and adjusted by separate water cooling system. The mass loss, the mass loss rate and the modification of the surface hardness are evaluated for different cavitation exposure intervals. The mass loss was measured by micro weighing scale and the surface hardness by the micro-hardness meter. The presented results indicates the significant improvement in the surface hardness for both tested materials.

  19. Dendrites fragmentation induced by oscillating cavitation bubbles in ultrasound field.

    PubMed

    Wang, S; Kang, J; Zhang, X; Guo, Z

    2018-02-01

    The fragmentation of the dendrites of succinonitrile (SCN)-2-wt.% acetone organic transparent alloy caused by ultrasound-induced cavitation bubbles was studied by using ultra-high-speed digital camera with a rate of 40,000fps. Real-time imaging reveals that the vibrating cavitation bubbles can fragment not only secondary arms but also the primary ones under high ultrasound power. The secondary arms always broke at their roots as a result of stress concentration induced by oscillated cavitation bubble and then ripped off from their primary arms. Generally the fragment process takes tens of milliseconds from bending to breaking, while the break always occurs immediately in less than 25μs. Copyright © 2017. Published by Elsevier B.V.

  20. A Study of Cavitation-Ignition Bubble Combustion

    NASA Technical Reports Server (NTRS)

    Nguyen, Quang-Viet; Jacqmin, David A.

    2005-01-01

    We present the results of an experimental and computational study of the physics and chemistry of cavitation-ignition bubble combustion (CIBC), a process that occurs when combustible gaseous mixtures are ignited by the high temperatures found inside a rapidly collapsing bubble. The CIBC process was modeled using a time-dependent compressible fluid-dynamics code that includes finite-rate chemistry. The model predicts that gas-phase reactions within the bubble produce CO and other gaseous by-products of combustion. In addition, heat and mechanical energy release through a bubble volume-expansion phase are also predicted by the model. We experimentally demonstrate the CIBC process using an ultrasonically excited cavitation flow reactor with various hydrocarbon-air mixtures in liquid water. Low concentrations (< 160 ppm) of carbon monoxide (CO) emissions from the ultrasonic reactor were measured, and found to be proportional to the acoustic excitation power. The results of the model were consistent with the measured experimental results. Based on the experimental findings, the computational model, and previous reports of the "micro-diesel effect" in industrial hydraulic systems, we conclude that CIBC is indeed possible and exists in ultrasonically- and hydrodynamically-induced cavitation. Finally, estimates of the utility of CIBC process as a means of powering an idealized heat engine are also presented.

  1. Influence of ultrasound power and frequency upon corrosion kinetics of zinc in saline media.

    PubMed

    Doche, M-L; Hihn, J-Y; Mandroyan, A; Viennet, R; Touyeras, F

    2003-10-01

    This paper is devoted to zinc corrosion and oxidation mechanism in an ultrasonically stirred aerated sodium sulfate electrolyte. It follows a previous study devoted to the influence of 20 kHz ultrasound upon zinc corrosion in NaOH electrolytes [Ultrason. Sonochemis. 8 (2001) 291]. In the present work, various ultrasound regimes were applied by changing the transmitted power and the wave frequency (20 and 40 kHz). Unlike NaOH electrolyte which turns the zinc electrode into a passive state, Na2SO4 saline media induces soft corrosion conditions. This allows a study of the combined effects of ultrasonically modified hydrodynamic and mechanical damage (cavitation) upon the zinc corrosion process. A series of initial experiments were carried out so as to determine the transmitted power and to characterize mass transfer distribution in the electrochemical cell. Zinc corrosion and oxidation process were subsequently studied with respect to the vibrating parameters. When exposed to a 20 kHz ultrasonic field, and provided that the electrode is situated at a maximum mass transfer point, the corrosion rate reaches values six to eight times greater than in silent conditions. The zinc oxidation reaction, in the absence of competitive reduction reactions, is also activated by ultrasound (20 and 40 kHz) but probably through a different process of surface activation.

  2. Physical and chemical mechanism underlying ultrasonically enhanced hydrochloric acid leaching of non-oxidative roasting of bastnaesite.

    PubMed

    Zhang, Dongliang; Li, Mei; Gao, Kai; Li, Jianfei; Yan, Yujun; Liu, Xingyu

    2017-11-01

    In this study, we investigated an alternative to the conventional hydrochloric acid leaching of roasted bastnaesite. The studies suggested that the rare earth oxyfluorides in non-oxidatively roasted bastnaesite can be selectively leached only at elevated temperatures Further, the Ce(IV) in oxidatively roasted bastnaesite does not leach readily at low temperatures, and it is difficult to induce it to form a complex with F - ions in order to increase the leaching efficiency. Moreover, it is inevitably reduced to Ce(III) at elevated temperatures. Thus, the ultrasonically-assisted hydrochloric acid leaching of non-oxidatively roasted bastnaesite was studied in detail, including, the effects of several process factors and the, physical and chemical mechanisms underlying the leaching process. The results show that the leaching rate for the ultrasonically assisted process at 55°C (65% rare earth oxides) is almost the same as that for the conventional leaching process at 85°C. Based on the obtained results, it is concluded that ultrasonic cavitation plays a key role in the proposed process, resulting not only in a high shear stress, which damages the solid surface, but also in the formation of hydroxyl radicals (OH) and hydrogen peroxide (H 2 O 2 ). Standard electrode potential analysis and experimental results indicate that Ce(III) isoxidized by the hydroxyl radicals to Ce(IV), which can be leached with F - ions in the form of a complex, and that the Ce(IV) can subsequently be reduced to Ce(III) by the H 2 O 2. This prevents the Cl - ions in the solution from being oxidized to form chlorine. These results imply that the ultrasonically-assisted process can be used for the leaching of non-oxidatively roasted bastnaesite at low temperatures in the absence of a reductant. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Optical Sound Generation and Amplification

    DTIC Science & Technology

    1983-01-15

    acoustic cavitation threshold of water with concentration of the polymer additives polyethylene oxide and guar gum . It was found that small amounts of...Technical Library 2800 Powder Mill Road Adelphi, Maryland 20783 1 copy 3 copies 1 copy 1 copy 1 copy 1 copy 1 copy Naval Air Development Center

  4. Simulation for Carbon Nanotube Dispersion and Microstructure Formation in CNTs/AZ91D Composite Fabricated by Ultrasonic Processing

    NASA Astrophysics Data System (ADS)

    Yang, Yuansheng; Zhao, Fuze; Feng, Xiaohui

    2017-10-01

    The dispersion of carbon nanotubes (CNTs) in AZ91D melt by ultrasonic processing and microstructure formation of CNTs/AZ91D composite were studied using numerical and physical simulations. The sound field and acoustic streaming were predicted using finite element method. Meanwhile, optimal immersion depth of the ultrasonic probe and suitable ultrasonic power were obtained. Single-bubble model was used to predict ultrasonic cavitation in AZ91D melt. The relationship between sound pressure amplitude and ultrasonic cavitation was established. Physical simulations of acoustic streaming and ultrasonic cavitation agreed well with the numerical simulations. It was confirmed that the dispersion of carbon nanotubes was remarkably improved by ultrasonic processing. Microstructure formation of CNTs/AZ91D composite was numerically simulated using cellular automation method. In addition, grain refinement was achieved and the growth of dendrites was changed due to the uniform dispersion of CNTs.

  5. Formation of a cavitation cluster in the vicinity of a quasi-empty rupture

    NASA Astrophysics Data System (ADS)

    Bol'shakova, E. S.; Kedrinskiy, V. K.

    2017-09-01

    The presentation deals with one of the experimental and numerical models of a quasi-empty rupture in the magma melt. This rupture is formed in the liquid layer of a distilled cavitating fluid under shock loading within the framework of the problem formulation with a small electromagnetic hydrodynamic shock tube. It is demonstrated that the rupture is shaped as a spherical segment, which retains its topology during the entire process of its evolution and collapsing. The dynamic behavior of the quasi-empty rupture is analyzed, and the growth of cavitating nuclei in the form of the boundary layer near the entire rupture interface is found. It is shown that rupture implosion is accompanied by the transformation of the bubble boundary layer to a cavitating cluster, which takes the form of a ring-shaped vortex floating upward to the free surface of the liquid layer. A p-κ mathematical model is formulated, and calculations are performed to investigate the implosion of a quasi-empty spherical cavity in the cavitating liquid, generation of a shock wave by this cavity, and dynamics of the bubble density growth in the cavitating cluster by five orders of magnitude.

  6. Lowering of the cavitation threshold in aqueous suspensions of porous silicon nanoparticles for sonodynamic therapy applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sviridov, A. P., E-mail: asagittarius89@gmail.com; Osminkina, L. A.; Nikolaev, A. L.

    2015-09-21

    A significant decrease of the cavitation threshold in aqueous suspensions of porous silicon nanoparticles (PSi NPs) with sizes about 100 nm as compared with pure water was observed for ultrasound irradiation (USI) with therapeutic frequency (0.88 MHz) and intensities (about 1 W/cm{sup 2}). This effect is explained by porous morphology of PSi NPs, which promotes the nucleation of cavitation bubbles. In vitro experiments revealed a suppression of the proliferation of cancer cells with the introduced PSi NPs after exposure to USI related to the enhanced cavitation processes, which led to the cell destruction. The obtained results demonstrate that PSi NPs are prospectivemore » for applications as sonosensitizers in mild cancer therapy.« less

  7. Light activated microbubbles for imaging and microsurgery

    NASA Astrophysics Data System (ADS)

    Cavigli, Lucia; Micheletti, Filippo; Tortoli, Paolo; Centi, Sonia; Lai, Sarah; Borri, Claudia; Rossi, Francesca; Ratto, Fulvio; Pini, Roberto

    2017-03-01

    Imaging and microsurgery procedures based on the photoacoustic effect have recently attracted much attention for cancer treatment. Light absorption in the nanosecond regime triggers thermoelastic processes that induce ultrasound emission and even cavitation. The ultrasound waves may be detected to reconstruct images, while cavitation may be exploited to kill malignant cells. The potential of gold nanorods as contrast agents for photoacoustic imaging has been extensively investigated, but still little is known about their use to trigger cavitation. Here, we investigated the influence of environment thermal properties on the ability of gold nanorods to trigger cavitation by probing the photoacoustic emission as a function of the excitation fluence. We are confident that these results will provide useful directions to the development of new strategies for therapies based on the photoacoustic effect.

  8. Controlled cavitation to augment SWL stone comminution: mechanistic insights in vitro.

    PubMed

    Duryea, Alexander P; Roberts, William W; Cain, Charles A; Hall, Timothy L

    2013-02-01

    Stone comminution in shock wave lithotripsy (SWL) has been documented to result from mechanical stresses conferred directly to the stone, as well as the activity of cavitational microbubbles. Studies have demonstrated that the presence of this cavitation activity is crucial for stone subdivision; however, its exact role in the comminution process remains somewhat weakly defined, in part because it is difficult to isolate the cavitational component from the shock waves themselves. In this study, we further explored the importance of cavitation in SWL stone comminution through the use of histotripsy ultrasound therapy. Histotripsy was used to target model stones designed to mimic the mid-range tensile fracture strength of naturally occurring cystine calculi with controlled cavitation at strategic time points in the SWL comminution process. All SWL was applied at a peak positive pressure (p+) of 34 MPa and a peak negative pressure (p-) of 8 MPa; a shock rate of 1 Hz was used. Histotripsy pulses had a p- of 33 MPa and were applied at a pulse repetition frequency (PRF) of 100 Hz. Ten model stones were sonicated in vitro with each of five different treatment schemes: A) 10 min of SWL (600 shocks) with 0.7 s of histotripsy interleaved between successive shocks (totaling to 42 000 pulses); B) 10 min of SWL (600 shocks) followed by 10 min of histotripsy applied in 0.7-s bursts (1 burst per second, totaling to 42 000 pulses); C) 10 min of histotripsy applied in 0.7-s bursts (42 000 pulses) followed by 10 min of SWL (600 shocks); D) 10 min of SWL only (600 shocks); E) 10 min of histotripsy only, applied in 0.7-s bursts (42 000 pulses). Following sonication, debris was collected and sieved through 8-, 6-, 4-, and 2-mm filters. It was found that scheme D, SWL only, generated a broad range of fragment sizes, with an average of 14.9 ± 24.1% of the original stone mass remaining > 8 mm. Scheme E, histotripsy only, eroded the surface of stones to tiny particulate debris that was small enough to pass through the finest filter used in this study (<2 mm), leaving behind a single primary stone piece (>8 mm) with mass 85.1 ± 1.6% of the original following truncated sonication. The combination of SWL and histotripsy (schemes A, B, and C) resulted in a shift in the size distribution toward smaller fragments and complete elimination of debris > 8 mm. When histotripsy-controlled cavitation was applied following SWL (B), the increase in exposed stone surface area afforded by shock wave stone subdivision led to enhanced cavitation erosion. When histotripsy-controlled cavitation was applied before SWL (C), it is likely that stone surface defects induced by cavitation erosion provided sites for crack nucleation and accelerated shock wave stone subdivision. Both of these effects are likely at play in the interleaved therapy (A), although shielding of shock waves by remnant histotripsy microbubble nuclei may have limited the efficacy of this scheme. Nevertheless, these results demonstrate the important role played by cavitation in the stone comminution process, and suggest that the application of controlled cavitation at strategic time points can provide an adjunct to traditional SWL therapy.

  9. High-temperature deformation and microstructural analysis for silicon nitride-scandium(III) oxide

    NASA Technical Reports Server (NTRS)

    Cheong, Deock-Soo; Sanders, William A.

    1992-01-01

    It was indicated that Si3N4 doped with Sc2O3 may exhibit high temperature mechanical properties superior to Si3N4 systems with various other oxide sintered additives. High temperature deformation of samples was studied by characterizing the microstructures before and after deformation. It was found that elements of the additive, such as Sc and O, exist in small amounts at very thin grain boundary layers and most of them stay in secondary phases at tripple and multiple grain boundary junctions. These secondary phases are devitrified as crystalline Sc2Si2O7. Deformation of the samples was dominated by cavitational processes rather than movements of dislocations. Thus the excellent deformation resistance of the samples at high temperature can be attributed to the very small thickness of the grain boundary layers and the crystalline secondary phase.

  10. Effect of ultrasound on dynamics characteristic of the cavitation bubble in grinding fluids during honing process.

    PubMed

    Guo, Ce; Zhu, Xijing

    2018-03-01

    The effect of ultrasound on generating and controlling the cavitation bubble of the grinding fluid during ultrasonic vibration honing was investigated. The grinding fluid on the surface of the honing stone was measured by utilizing the digital microscope VHX-600ESO. Based on analyzing the cavitation mechanism of the grinding fluid, the bubble dynamics model under conventional honing (CH) and ultrasonic vibration honing (UVH) was established respectively. Difference of dynamic behaviors of the bubble between the cases in UVH and CH was compared respectively, and the effects of acoustic amplitude and ultrasonic frequency on the bubble dynamics were simulated numerically using the Runge-Kutta fourth order method with variable step size adaptive control. Finally, the cavitation intensity of grinding fluids under ultrasound was measured quantitatively using acoustimeter. The results showed that the grinding fluid subjected to ultrasound can generate many bubbles and further forms numerous groups of araneose cavitation bubbles on the surface of the honing stone. The oscillation of the bubble under UVH is more intense than the case under CH, and the maximum velocity of the bubble wall under UVH is higher two magnitudes than the case under CH. For lower acoustic amplitude, the dynamic behaviors of the bubble under UVH are similar to that case under CH. As increasing acoustic amplitude, the cavitation intensity of the bubble is growing increased. Honing pressure has an inhabitation effect on cavitation effect of the grinding fluid. The perfect performance of cavitation of the grinding fluid can be obtained when the device of UVH is in the resonance. However, the cavitation intensity of the grinding fluid can be growing weakened with increasing ultrasonic frequency, when the device of UVH is in the off-resonance. The experimental results agree with the theoretical and numerical analysis, which provides a method for exploring applications of the cavitation effect in ultrasonic assisted machining. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Rotating Balances Used for Fluid Pump Testing

    NASA Technical Reports Server (NTRS)

    Skelley, Stephen; Mulder, Andrew

    2014-01-01

    Marshall Space Flight Center has developed and demonstrated two direct read force and moment balances for sensing and resolving the hydrodynamic loads on rotating fluid machinery. These rotating balances consist of a series of stainless steel flexures instrumented with semiconductor type, unidirectional strain gauges arranged into six bridges, then sealed and waterproofed, for use fully submerged in degassed water at rotational speeds up to six thousand revolutions per minute. The balances are used to measure the forces and moments due to the onset and presence of cavitation or other hydrodynamic phenomena on subscale replicas of rocket engine turbomachinery, principally axial pumps (inducers) designed specifically to operate in a cavitating environment. The balances are inserted into the drive assembly with power to and signal from the sensors routed through the drive shaft and out through an air-cooled twenty-channel slip ring. High frequency data - balance forces and moments as well as extensive, flush-mounted pressures around the rotating component periphery - are acquired via a high-speed analog to digital data acquisition system while the test rig conditions are varied continuously. The data acquisition and correction process is described, including the in-situ verifications that are performed to quantify and correct for known system effects such as mechanical imbalance, "added mass," buoyancy, mechanical resonance, and electrical bias. Examples of four types of cavitation oscillations for two typical inducers are described in the laboratory (pressure) and rotating (force) frames: 1) attached, symmetric cavitation, 2) rotating cavitation, 3) attached, asymmetric cavitation, and 4) cavitation surge. Rotating and asymmetric cavitation generate a corresponding unbalanced radial force on the rotating assembly while cavitation surge generates an axial force. Attached, symmetric cavitation induces no measurable force. The frequency of the forces can be determined a priori from the pressure environment while the magnitude of the hydrodynamic force is proportional to the pressure unsteadiness.

  12. Numerical analyses of ventilated cavitation over a 2-D NACA0015 hydrofoil using two turbulence modeling methods

    NASA Astrophysics Data System (ADS)

    Yang, Dan-dan; Yu, An; Ji, Bin; Zhou, Jia-jian; Luo, Xian-wu

    2018-04-01

    The present paper studies the ventilated cavitation over a NACA0015 hydrofoil by numerical methods. The corresponding cavity evolutions are obtained at three ventilation rates by using the level set method. To depict the complicated turbulent flow structure, the filter-based density corrected model (FBDCM) and the modified partially-averaged Navier-Stokes (MPANS) model are applied in the present numerical analyses. It is indicated that the predicted results of the cavitation shedding dynamics by both turbulence models agree fairly well with the experimental data. It is also noted that the shedding frequency and the super cavity length predicted by the MPANS method are closer to the experiment data as compared to that predicted by the FBDCM model. The simulation results show that in the ventilated cavitation, the vapor cavity and the air cavity have the same shedding frequency. As the ventilated rate increases, the vapor cavity is depressed rapidly. The cavitation-vortex interaction in the ventilated cavitation is studied based on the vorticity transport equation (VTE) and the Lagrangian coherent structure (LCS). Those results demonstrate that the vortex dilatation and baroclinic torque terms are highly dependent on the evolution of the cavitation. In addition, from the LCSs and the tracer particles in the flow field, one may see the process from the attached cavity to the cloud cavity.

  13. CAVITATION SOUNDS DURING CERVICOTHORACIC SPINAL MANIPULATION

    PubMed Central

    Mourad, Firas; Zingoni, Andrea; Iorio, Raffaele; Perreault, Thomas; Zacharko, Noah; de las Peñas, César Fernández; Butts, Raymond; Cleland, Joshua A.

    2017-01-01

    Background No study has previously investigated the side, duration or number of audible cavitation sounds during high-velocity low-amplitude (HVLA) thrust manipulation to the cervicothoracic spine. Purpose The primary purpose was to determine which side of the spine cavitates during cervicothoracic junction (CTJ) HVLA thrust manipulation. Secondary aims were to calculate the average number of cavitations, the duration of cervicothoracic thrust manipulation, and the duration of a single cavitation. Study Design Quasi-experimental study Methods Thirty-two patients with upper trapezius myalgia received two cervicothoracic HVLA thrust manipulations targeting the right and left T1-2 articulation, respectively. Two high sampling rate accelerometers were secured bilaterally 25 mm lateral to midline of the T1-2 interspace. For each manipulation, two audio signals were extracted using Short-Time Fourier Transformation (STFT) and singularly processed via spectrogram calculation in order to evaluate the frequency content and number of instantaneous energy bursts of both signals over time for each side of the CTJ. Result Unilateral cavitation sounds were detected in 53 (91.4%) of 58 cervicothoracic HVLA thrust manipulations and bilateral cavitation sounds were detected in just five (8.6%) of the 58 thrust manipulations; that is, cavitation was significantly (p<0.001) more likely to occur unilaterally than bilaterally. In addition, cavitation was significantly (p<0.0001) more likely to occur on the side contralateral to the clinician's short-lever applicator. The mean number of audible cavitations per manipulation was 4.35 (95% CI 2.88, 5.76). The mean duration of a single manipulation was 60.77 ms (95% CI 28.25, 97.42) and the mean duration of a single audible cavitation was 4.13 ms (95% CI 0.82, 7.46). In addition to single-peak and multi-peak energy bursts, spectrogram analysis also demonstrated high frequency sounds, low frequency sounds, and sounds of multiple frequencies for all 58 manipulations. Discussion Cavitation was significantly more likely to occur unilaterally, and on the side contralateral to the short-lever applicator contact, during cervicothoracic HVLA thrust manipulation. Clinicians should expect multiple cavitation sounds when performing HVLA thrust manipulation to the CTJ. Due to the presence of multi-peak energy bursts and sounds of multiple frequencies, the cavitation hypothesis (i.e. intra-articular gas bubble collapse) alone appears unable to explain all of the audible sounds during HVLA thrust manipulation, and the possibility remains that several phenomena may be occurring simultaneously. Level of Evidence 2b PMID:28900571

  14. Controlled permeation of cell membrane by single bubble acoustic cavitation

    PubMed Central

    Zhou, Y.; Yang, K.; Cui, J.; Ye, J. Y.; Deng, C. X.

    2011-01-01

    Sonoporation is the membrane disruption generated by ultrasound and has been exploited as a non-viral strategy for drug and gene delivery. Acoustic cavitation of microbubbles has been recognized to play an important role in sonoporation. However, due to the lack of adequate techniques for precise control of cavitation activities and real-time assessment of the resulting sub-micron process of sonoporation, limited knowledge has been available regarding the detail processes and correlation of cavitation with membrane disruption at the single cell level. In the current study, we developed a combined approach including optical, acoustic, and electrophysiological techniques to enable synchronized manipulation, imaging, and measurement of cavitation of single bubbles and the resulting cell membrane disruption in real-time. Using a self-focused femtosecond laser and high frequency (7.44 MHz) pulses, a single microbubble was generated and positioned at a desired distance from the membrane of a Xenopus oocyte. Cavitation of the bubble was achieved by applying a low frequency (1.5 MHz) ultrasound pulse (duration 13.3 or 40 µs) to induce bubble collapse. Disruption of the cell membrane was assessed by the increase in the transmembrane current (TMC) of the cell under voltage clamp. Simultaneous high-speed bright field imaging of cavitation and measurements of the TMC were obtained to correlate the ultrasound-generated bubble activities with the cell membrane poration. The change in membrane permeability was directly associated with the formation of a sub-micrometer pore from a local membrane rupture generated by bubble collapse or bubble compression depending on ultrasound amplitude and duration. The impact of the bubble collapse on membrane permeation decreased rapidly with increasing distance (D) between the bubble (diameter d) and the cell membrane. The effective range of cavitation impact on membrane poration was determined to be D/d = 0.75. The maximum mean radius of the pores was estimated from the measured TMC to be 0.106 ± 0.032 µm (n = 70) for acoustic pressure of 1.5 MPa (duration 13.3 µs), and increased to 0.171 ± 0.030 µm (n = 125) for acoustic pressure of 1.7 MPa and to 0.182 ± 0.052 µm (n=112) for a pulse duration of 40 µs (1.5 MPa). These results from controlled cell membrane permeation by cavitation of single bubbles revealed insights and key factors affecting sonoporation at the single cell level. PMID:21945682

  15. Effects of power ultrasound on oxidation and structure of beef proteins during curing processing.

    PubMed

    Kang, Da-Cheng; Zou, Yun-He; Cheng, Yu-Ping; Xing, Lu-Juan; Zhou, Guang-Hong; Zhang, Wan-Gang

    2016-11-01

    The aim of this study was to evaluate the effects of power ultrasound intensity (PUS, 2.39, 6.23, 11.32 and 20.96Wcm(-2)) and treatment time (30, 60, 90 and 120min) on the oxidation and structure of beef proteins during the brining procedure with 6% NaCl concentration. The investigation was conducted with an ultrasonic generator with the frequency of 20kHz and fresh beef at 48h after slaughter. Analysis of TBARS (Thiobarbituric acid reactive substances) contents showed that PUS treatment significantly increased the extent of lipid oxidation compared to static brining (P<0.05). As indicators of protein oxidation, the carbonyl contents were significantly affected by PUS (P<0.05). SDS-PAGE analysis showed that PUS treatment increased protein aggregation through disulfide cross-linking, indicated by the decreasing content of total sulfhydryl groups which would contribute to protein oxidation. In addition, changes in protein structure after PUS treatment are suggested by the increases in free sulfhydryl residues and protein surface hydrophobicity. Fourier transformed infrared spectroscopy (FTIR) provided further information about the changes in protein secondary structures with increases in β-sheet and decreases in α-helix contents after PUS processing. These results indicate that PUS leads to changes in structures and oxidation of beef proteins caused by mechanical effects of cavitation and the resultant generation of free radicals. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Two reference time scales for studying the dynamic cavitation of liquid films

    NASA Technical Reports Server (NTRS)

    Sun, D. C.; Brewe, D. E.

    1992-01-01

    Two formulas, one for the characteristic time of filling a void with the vapor of the surrounding liquid, and one of filling the void by diffusion of the dissolved gas in the liquid, are derived. By comparing these time scales with that of the dynamic operation of oil film bearings, it is concluded that the evaporation process is usually fast enough to fill the cavitation bubble with oil vapor; whereas the diffusion process is much too slow for the dissolved air to liberate itself and enter the cavitation bubble. These results imply that the formation of a two phase fluid in dynamically loaded bearings, as often reported in the literature, is caused by air entrainment. They further indicate a way to simplify the treatment of the dynamic problem of bubble evolution.

  17. Removal of blue-green algae using the hybrid method of hydrodynamic cavitation and ozonation.

    PubMed

    Wu, Zhilin; Shen, Haifeng; Ondruschka, Bernd; Zhang, Yongchun; Wang, Weimin; Bremner, David H

    2012-10-15

    A suspension of Microcystis aeruginosa (30 μg L(-1)chlorophyll a) was circulated in a hydrodynamic cavitation device and ozone was introduced at the suction side of the pump. The removal of algae over 10 min using hydrodynamic cavitation alone and ozone alone is less than 15% and 35%, respectively. The destruction of algae rises significantly from 24% in the absence of the orifice to 91% with the optimized orifice on 5 min of processing using hydrodynamic cavitation along with ozone (HC/O(3)) and the utilization of ozone increases from 32% to 61%. Interestingly, the suction process is more effective than the extrusion method (positive pressure) and the optimal bulk temperature for algal elimination was found to be 20 °C. Increasing the input concentration of ozone is favorable for the removal of algae but leads to a greater loss of ozone and a decrease in the utilization of ozone. Under the optimal conditions, the algal cells and chlorophyll a are completely destroyed in 10 min by use of the hybrid method. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Detection of cystic structures using pulsed ultrasonically induced resonant cavitation

    NASA Technical Reports Server (NTRS)

    Bar-Cohen, Yoseph (Inventor); Kovach, John S. (Inventor)

    2002-01-01

    Apparatus and method for early detection of cystic structures indicative of ovarian and breast cancers uses ultrasonic wave energy at a unique resonance frequency for inducing cavitation in cystic fluid characteristic of cystic structures in the ovaries associated with ovarian cancer, and in cystic structures in the breast associated with breast cancer. Induced cavitation bubbles in the cystic fluid implode, creating implosion waves which are detected by ultrasonic receiving transducers attached to the abdomen of the patient. Triangulation of the ultrasonic receiving transducers enables the received signals to be processed and analyzed to identify the location and structure of the cyst.

  19. Visualisation of diesel injector with neutron imaging

    NASA Astrophysics Data System (ADS)

    Lehmann, E.; Grünzweig, C.; Jollet, S.; Kaiser, M.; Hansen, H.; Dinkelacker, F.

    2015-12-01

    The injection process of diesel engines influences the pollutant emissions. The spray formation is significantly influenced by the internal flow of the injector. One of the key parameters here is the generation of cavitation caused by the geometry and the needle lift. In modern diesel engines the injection pressure is established up to 3000 bar. The details of the flow and phase change processes inside the injector are of increasing importance for such injectors. With these experimental measurements the validation of multiphase and cavitation models is possible for the high pressure range. Here, for instance, cavitation effects can occur. Cavitation effects in the injection port area destabilize the emergent fuel jet and improve the jet break-up. The design of the injection system in direct-injection diesel engines is an important challenge, as the jet breakup, the atomization and the mixture formation in the combustion chamber are closely linked. These factors have a direct impact on emissions, fuel consumption and performance of an engine. The shape of the spray at the outlet is determined by the internal flow of the nozzle. Here, geometrical parameters, the injection pressure, the injection duration and the cavitation phenomena play a major role. In this work, the flow dependency in the nozzles are analysed with the Neutron-Imaging. The great advantage of this method is the penetrability of the steel structure while a high contrast to the fuel is given due to the interaction of the neutrons with the hydrogen amount. Compared to other methods (optical with glass structures) we can apply real components under highest pressure conditions. During the steady state phase of the injection various cavitation phenomena are visible in the injector, being influenced by the nozzle geometry and the fuel pressure. Different characteristics of cavitation in the sac and spray hole can be detected, and the spray formation in the primary breakup zone is influenced.

  20. Spatial and temporal observation of phase-shift nano-emulsions assisted cavitation and ablation during focused ultrasound exposure.

    PubMed

    Qiao, Yangzi; Zong, Yujin; Yin, Hui; Chang, Nan; Li, Zhaopeng; Wan, Mingxi

    2014-09-01

    Phase-shift nano-emulsions (PSNEs) with a small initial diameter in nanoscale have the potential to leak out of the blood vessels and to accumulate at the target point of tissue. At desired location, PSNEs can undergo acoustic droplet vaporization (ADV) process, change into gas bubbles and enhance focused ultrasound efficiency. The threshold of droplet vaporization and influence of acoustic parameters have always been research hotspots in order to spatially control the potential of bioeffects and optimize experimental conditions. However, when the pressure is much higher than PSNEs' vaporization threshold, there were little reports on their cavitation and thermal effects. In this study, PSNEs induced cavitation and ablation effects during pulsed high-intensity focused ultrasound (HIFU) exposure were investigated, including the spatial and temporal information and the influence of acoustic parameters. Two kinds of tissue-mimicking phantoms with uniform PSNEs were prepared because of their optical transparency. The Sonoluminescence (SL) method was employed to visualize the cavitation activities. And the ablation process was observed as the heat deposition could produce white lesion. Precisely controlled HIFU cavitation and ablation can be realized at a relatively low input power. But when the input power was high, PSNEs can accelerate cavitation and ablation in pre-focal region. The cavitation happened layer by layer advancing the transducer. While the lesion appeared to be separated into two parts, one in pre-focal region stemmed from one point and grew quickly, the other in focal region grew much more slowly. The influence of duty cycle has also been examined. Longer pulse off time would cause heat transfer to the surrounding media, and generate smaller lesion. On the other hand, this would give outer layer bubbles enough time to dissolve, and inner bubbles can undergo violent collapse and emit bright light. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Hydrodynamic cavitation as a strategy to enhance the efficiency of lignocellulosic biomass pretreatment.

    PubMed

    Terán Hilares, Ruly; Ramos, Lucas; da Silva, Silvio Silvério; Dragone, Giuliano; Mussatto, Solange I; Santos, Júlio César Dos

    2018-06-01

    Hydrodynamic cavitation (HC) is a process technology with potential for application in different areas including environmental, food processing, and biofuels production. Although HC is an undesirable phenomenon for hydraulic equipment, the net energy released during this process is enough to accelerate certain chemical reactions. The application of cavitation energy to enhance the efficiency of lignocellulosic biomass pretreatment is an interesting strategy proposed for integration in biorefineries for the production of bio-based products. Moreover, the use of an HC-assisted process was demonstrated as an attractive alternative when compared to other conventional pretreatment technologies. This is not only due to high pretreatment efficiency resulting in high enzymatic digestibility of carbohydrate fraction, but also, by its high energy efficiency, simple configuration, and construction of systems, besides the possibility of using on the large scale. This paper gives an overview regarding HC technology and its potential for application on the pretreatment of lignocellulosic biomass. The parameters affecting this process and the perspectives for future developments in this area are also presented and discussed.

  2. Studies on the preparation of Caro’s acid by ultrasonic enhanced electrochemistry

    NASA Astrophysics Data System (ADS)

    Li, Linbo; Yu, Zeli; Hong, Tao; Fang, Zhao; Peng, Jishi; Yang, Zhao

    2017-06-01

    Ultrasonic cavitation effects can generate hydroxyl radicals and high energy, which is widely applied in the field of oxidation currently. Ultrasound-enhanced electrochemical is used to prepare Caro’s acid, which improves the generate rate of Caro’s acid. In this article, the influences of ultrasonic frequency and ultrasonic power on the electrolysis voltage, electrolyte temperature, electrolyte concentration and the concentration of additive in the process of electrochemical preparation of Caro’s acid was studied. And the optimal production conditions were determined. The research results showed that ultrasonic can significantly improve the production of Caro’s acid and the product can increase by about 20 g/L under the best condition.

  3. Imaging and analysis of individual cavitation microbubbles around dental ultrasonic scalers.

    PubMed

    Vyas, N; Dehghani, H; Sammons, R L; Wang, Q X; Leppinen, D M; Walmsley, A D

    2017-11-01

    Cavitation is a potentially effective and less damaging method of removing biofilm from biomaterial surfaces. The aim of this study is to characterise individual microbubbles around ultrasonic scaler tips using high speed imaging and image processing. This information will provide improved understanding on the disruption of dental biofilm and give insights into how the instruments can be optimised for ultrasonic cleaning. Individual cavitation microbubbles around ultrasonic scalers were analysed using high speed recordings up to a million frames per second with image processing of the bubble movement. The radius and rate of bubble growth together with the collapse was calculated by tracking multiple points on bubbles over time. The tracking method to determine bubble speed demonstrated good inter-rater reliability (intra class correlation coefficient: 0.993) and can therefore be a useful method to apply in future studies. The bubble speed increased over its oscillation cycle and a maximum of 27ms -1 was recorded during the collapse phase. The maximum bubble radii ranged from 40 to 80μm. Bubble growth was observed when the ultrasonic scaler tip receded from an area and similarly bubble collapse was observed when the tip moved towards an area, corresponding to locations of low pressure around the scaler tip. Previous work shows that this cavitation is involved in biofilm removal. Future experimental work can be based on these findings by using the protocols developed to experimentally analyse cavitation around various clinical instruments and comparing with theoretical calculations. This will help to determine the main cleaning mechanisms of cavitation and how clinical instruments such as ultrasonic scalers can be optimised. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  4. Using the cavitation collapse time to indicate the extent of histotripsy-induced tissue fractionation

    NASA Astrophysics Data System (ADS)

    Macoskey, J. J.; Choi, S. W.; Hall, T. L.; Vlaisavljevich, E.; Lundt, J. E.; Lee, F. T., Jr.; Johnsen, E.; Cain, C. A.; Xu, Z.

    2018-03-01

    Histotripsy is an ultrasonic tissue ablation method based on acoustic cavitation. It has been shown that cavitation dynamics change depending on the mechanical properties of the host medium. During histotripsy treatment, the target-tissue is gradually fractionated and eventually liquefied to acellular homogenate. In this study, the change in the collapse time (t col) of the cavitation bubble cloud over the course of histotripsy treatment is investigated as an indicator for progression of the tissue fractionation process throughout treatment. A 500 kHz histotripsy transducer is used to generate single-location lesions within tissue-mimicking agar phantoms of varying stiffness levels as well as ex vivo bovine liver samples. Cavitation collapse signals are acquired with broadband hydrophones, and cavitation is imaged optically using a high-speed camera in transparent tissue-mimicking phantoms. The high-speed-camera-acquired measurements of t col validate the acoustic hydrophone measurements. Increases in t col are observed both with decreasing phantom stiffness and throughout histotripsy treatment with increasing number of pulses applied. The increasing trend of t col throughout the histotripsy treatment correlates well with the progression of lesion formation generated in tissue-mimicking phantoms (R 2  =  0.87). Finally, the increasing trend of t col over the histotripsy treatment is validated in ex vivo bovine liver.

  5. Coupling of Acoustic Cavitation with Dem-Based Particle Solvers for Modeling De-agglomeration of Particle Clusters in Liquid Metals

    NASA Astrophysics Data System (ADS)

    Manoylov, Anton; Lebon, Bruno; Djambazov, Georgi; Pericleous, Koulis

    2017-11-01

    The aerospace and automotive industries are seeking advanced materials with low weight yet high strength and durability. Aluminum and magnesium-based metal matrix composites with ceramic micro- and nano-reinforcements promise the desirable properties. However, larger surface-area-to-volume ratio in micro- and especially nanoparticles gives rise to van der Waals and adhesion forces that cause the particles to agglomerate in clusters. Such clusters lead to adverse effects on final properties, no longer acting as dislocation anchors but instead becoming defects. Also, agglomeration causes the particle distribution to become uneven, leading to inconsistent properties. To break up clusters, ultrasonic processing may be used via an immersed sonotrode, or alternatively via electromagnetic vibration. This paper combines a fundamental study of acoustic cavitation in liquid aluminum with a study of the interaction forces causing particles to agglomerate, as well as mechanisms of cluster breakup. A non-linear acoustic cavitation model utilizing pressure waves produced by an immersed horn is presented, and then applied to cavitation in liquid aluminum. Physical quantities related to fluid flow and quantities specific to the cavitation solver are passed to a discrete element method particles model. The coupled system is then used for a detailed study of clusters' breakup by cavitation.

  6. Degradation of diclofenac sodium using combined processes based on hydrodynamic cavitation and heterogeneous photocatalysis.

    PubMed

    Bagal, Manisha V; Gogate, Parag R

    2014-05-01

    Diclofenac sodium, a widely detected pharmaceutical drug in wastewater samples, has been selected as a model pollutant for degradation using novel combined approach of hydrodynamic cavitation and heterogeneous photocatalysis. A slit venturi has been used as cavitating device in the hydrodynamic cavitation reactor. The effect of various operating parameters such as inlet fluid pressure (2-4 bar) and initial pH of the solution (4-7.5) on the extent of degradation have been studied. The maximum extent of degradation of diclofenac sodium was obtained at inlet fluid pressure of 3 bar and initial pH as 4 using hydrodynamic cavitation alone. The loadings of TiO2 and H2O2 have been optimised to maximise the extent of degradation of diclofenac sodium. Kinetic study revealed that the degradation of diclofenac sodium fitted first order kinetics over the selected range of operating protocols. It has been observed that combination of hydrodynamic cavitation with UV, UV/TiO2 and UV/TiO2/H2O2 results in enhanced extents of degradation as compared to the individual schemes. The maximum extent of degradation as 95% with 76% reduction in TOC has been observed using hydrodynamic cavitation in conjunction with UV/TiO2/H2O2 under the optimised operating conditions. The diclofenac sodium degradation byproducts have been identified using LC/MS analysis. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Numerical modelling of ultrasonic waves in a bubbly Newtonian liquid using a high-order acoustic cavitation model.

    PubMed

    Lebon, G S Bruno; Tzanakis, I; Djambazov, G; Pericleous, K; Eskin, D G

    2017-07-01

    To address difficulties in treating large volumes of liquid metal with ultrasound, a fundamental study of acoustic cavitation in liquid aluminium, expressed in an experimentally validated numerical model, is presented in this paper. To improve the understanding of the cavitation process, a non-linear acoustic model is validated against reference water pressure measurements from acoustic waves produced by an immersed horn. A high-order method is used to discretize the wave equation in both space and time. These discretized equations are coupled to the Rayleigh-Plesset equation using two different time scales to couple the bubble and flow scales, resulting in a stable, fast, and reasonably accurate method for the prediction of acoustic pressures in cavitating liquids. This method is then applied to the context of treatment of liquid aluminium, where it predicts that the most intense cavitation activity is localised below the vibrating horn and estimates the acoustic decay below the sonotrode with reasonable qualitative agreement with experimental data. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  8. Efficient and controllable thermal ablation induced by short-pulsed HIFU sequence assisted with perfluorohexane nanodroplets.

    PubMed

    Chang, Nan; Lu, Shukuan; Qin, Dui; Xu, Tianqi; Han, Meng; Wang, Supin; Wan, Mingxi

    2018-07-01

    A HIFU sequence with extremely short pulse duration and high pulse repetition frequency can achieve thermal ablation at a low acoustic power using inertial cavitation. Because of its cavitation-dependent property, the therapeutic outcome is unreliable when the treatment zone lacks cavitation nuclei. To overcome this intrinsic limitation, we introduced perfluorocarbon nanodroplets as extra cavitation nuclei into short-pulsed HIFU-mediated thermal ablation. Two types of nanodroplets were used with perfluorohexane (PFH) as the core material coated with bovine serum albumin (BSA) or an anionic fluorosurfactant (FS) to demonstrate the feasibility of this study. The thermal ablation process was recorded by high-speed photography. The inertial cavitation activity during the ablation was revealed by sonoluminescence (SL). The high-speed photography results show that the thermal ablation volume increased by ∼643% and 596% with BSA-PFH and FS-PFH, respectively, than the short-pulsed HIFU alone at an acoustic power of 19.5 W. Using nanodroplets, much larger ablation volumes were created even at a much lower acoustic power. Meanwhile, the treatment time for ablating a desired volume significantly reduced in the presence of nanodroplets. Moreover, by adjusting the treatment time, lesion migration towards the HIFU transducer could also be avoided. The SL results show that the thermal lesion shape was significantly dependent on the inertial cavitation in this short-pulsed HIFU-mediated thermal ablation. The inertial cavitation activity became more predictable by using nanodroplets. Therefore, the introduction of PFH nanodroplets as extra cavitation nuclei made the short-pulsed HIFU thermal ablation more efficient by increasing the ablation volume and speed, and more controllable by reducing the acoustic power and preventing lesion migration. Copyright © 2018. Published by Elsevier B.V.

  9. Study of physical and biological factors involved in the disruption of E. coli by hydrodynamic cavitation.

    PubMed

    Balasundaram, B; Harrison, S T L

    2006-01-01

    Hydrodynamic cavitation results in flow restriction in a flow system causing rapid pressure fluctuations and significant fluid forces. These can be harnessed to mediate microbial cell damage. Hydrodynamic cavitation was studied for the partial disruption of E. coli and selective release of specific proteins relative to the total soluble protein. The effects of the cavitation number, the number of passes, and the specific growth rate of E. coli on the release of periplasmic and cytoplasmic proteins were studied. At the optimum cavitation number of 0.17 for this experimental configuration, 48% of the total soluble protein, 88% of acid phosphatase, and 67% of beta-galactosidase were released by hydrodynamic cavitation in comparison with the maximum release attained using multiple passes through the French Press. The higher release of the acid phosphatase over the total soluble protein suggested preferred release of periplasmic compounds. This was supported by SDS-PAGE analysis. The absence of micronization of cell material resulting in the potential for ease of solid-liquid separation downstream of the cell disruption operation was confirmed by TEM microscopy. E. coli cells cultivated at a higher specific growth rate (0.36 h(-1)) were more easily disrupted than slower grown cells (0.11 h(-1)). The specific activity of the enzyme of interest released by hydrodynamic cavitation, defined as the units of enzyme in solution per milligram of total soluble protein, was greater than that obtained on release by the French Press, high-pressure homogenization, osmotic shock, and EDTA treatment. The selectivity offered indicates the potential of enzyme release by hydrodynamic cavitation to ease the purification in the subsequent downstream processing.

  10. Monitoring of transient cavitation induced by ultrasound and intense pulsed light in presence of gold nanoparticles.

    PubMed

    Sazgarnia, Ameneh; Shanei, Ahmad; Shanei, Mohammad Mahdi

    2014-01-01

    One of the most important challenges in medical treatment is invention of a minimally invasive approach in order to induce lethal damages to cancer cells. Application of high intensity focused ultrasound can be beneficial to achieve this goal via the cavitation process. Existence of the particles and vapor in a liquid decreases the ultrasonic intensity threshold required for cavitation onset. In this study, synergism of intense pulsed light (IPL) and gold nanoparticles (GNPs) has been investigated as a means of providing nucleation sites for acoustic cavitation. Several approaches have been reported with the aim of cavitation monitoring. We conducted the experiments on the basis of sonochemiluminescence (SCL) and chemical dosimetric methods. The acoustic cavitation activity was investigated by determining the integrated SCL signal acquired over polyacrylamide gel phantoms containing luminol in the presence and absence of GNPs in the wavelength range of 400-500 nm using a spectrometer equipped with cooled charged coupled devices (CCD) during irradiation by different intensities of 1 MHz ultrasound and IPL pulses. In order to confirm these results, the terephthalic acid chemical dosimeter was utilized as well. The SCL signal recorded in the gel phantoms containing GNPs at different intensities of ultrasound in the presence of intense pulsed light was higher than the gel phantoms without GNPs. These results have been confirmed by the obtained data from the chemical dosimetry method. Acoustic cavitation in the presence of GNPs and intense pulsed light has been suggested as a new approach designed for decreasing threshold intensity of acoustic cavitation and improving targeted therapeutic effects. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. Vortex flow and cavitation in diesel injector nozzles

    NASA Astrophysics Data System (ADS)

    Andriotis, A.; Gavaises, M.; Arcoumanis, C.

    Flow visualization as well as three-dimensional cavitating flow simulations have been employed for characterizing the formation of cavitation inside transparent replicas of fuel injector valves used in low-speed two-stroke diesel engines. The designs tested have incorporated five-hole nozzles with cylindrical as well as tapered holes operating at different fixed needle lift positions. High-speed images have revealed the formation of an unsteady vapour structure upstream of the injection holes inside the nozzle volume, which is referred to as . Computation of the flow distribution and combination with three-dimensional reconstruction of the location of the strings inside the nozzle volume has revealed that strings are found at the core of recirculation zones; they originate either from pre-existing cavitation sites forming at sharp corners inside the nozzle where the pressure falls below the vapour pressure of the flowing liquid, or even from suction of outside air downstream of the hole exit. Processing of the acquired images has allowed estimation of the mean location and probability of appearance of the cavitating strings in the three-dimensional space as a function of needle lift, cavitation and Reynolds number. The frequency of appearance of the strings has been correlated with the Strouhal number of the vortices developing inside the sac volume; the latter has been found to be a function of needle lift and hole shape. The presence of strings has significantly affected the flow conditions at the nozzle exit, influencing the injected spray. The cavitation structures formed inside the injection holes are significantly altered by the presence of cavitation strings and are jointly responsible for up to 10% variation in the instantaneous fuel injection quantity. Extrapolation using model predictions for real-size injectors operating at realistic injection pressures indicates that cavitation strings are expected to appear within the time scales of typical injection events, implying significant hole-to-hole and cycle-to-cycle variations during the corresponding spray development.

  12. Excellent mechanical properties and resistance to cavitation erosion for an ultra-low carbon CrMnN stainless steel through quenching and partitioning treatment

    NASA Astrophysics Data System (ADS)

    Zhou, Ze-an; Fu, Wan-tang; Zhu, Zhe; Li, Bin; Shi, Zhong-ping; Sun, Shu-hua

    2018-05-01

    The retained austenite content (RAC), the mechanical properties, and the resistance to cavitation erosion (CE) of the 00Cr13Mn8MoN steel after quenching and partitioning (Q&P) processing were investigated. The results show that the Q&P process affected the RAC, which reached the maximum value after partitioning at 400°C for 10 min. The tensile strength of the steel slightly decreased with increasing partitioning temperature and time. However, the elongation and product of strength and elongation first increased and then decreased. The sample partitioned at 400°C for 10 min exhibited the optimal property: a strength-ductility of 23.8 GPa·%. The resistance to CE for the 00Cr13Mn8MoN steel treated by the Q&P process was improved due to work hardening, spalling, and cavitation-induced martensitic transformation of the retained austenite.

  13. Influence of mixing and ultrasound frequency on antisolvent crystallisation of sodium chloride.

    PubMed

    Lee, Judy; Ashokkumar, Muthupandian; Kentish, Sandra E

    2014-01-01

    Ultrasound is known to promote nucleation of crystals and produce a narrower size distribution in a controlled and reproducible manner for the crystallisation process. Although there are various theories that suggest cavitation bubbles are responsible for sonocrystallisation, most studies use power ultrasonic horns that generate both intense shear and cavitation and this can mask the role that cavitation bubbles play. High frequency ultrasound from a plate transducer can be used to examine the effect of cavitation bubbles without the intense shear effect. This study reports the crystal size and morphology with various mixing speeds and ultrasound frequencies. The results show high frequency ultrasound produced sodium chloride crystals of similar size distribution as an ultrasonic horn. In addition, ultrasound generated sodium chloride crystals having a more symmetrical cubic structure compared to crystals produced by a high shear mixer. Copyright © 2013 Elsevier B.V. All rights reserved.

  14. Sonoporation of adherent cells under regulated ultrasound cavitation conditions.

    PubMed

    Muleki Seya, Pauline; Fouqueray, Manuela; Ngo, Jacqueline; Poizat, Adrien; Inserra, Claude; Béra, Jean-Christophe

    2015-04-01

    A sonoporation device dedicated to the adherent cell monolayer has been implemented with a regulation process allowing the real-time monitoring and control of inertial cavitation activity. Use of the cavitation-regulated device revealed first that adherent cell sonoporation efficiency is related to inertial cavitation activity, without inducing additional cell mortality. Reproducibility is enhanced for the highest sonoporation rates (up to 17%); sonoporation efficiency can reach 26% when advantage is taken of the standing wave acoustic configuration by applying a frequency sweep with ultrasound frequency tuned to the modal acoustic modes of the cavity. This device allows sonoporation of adherent and suspended cells, and the use of regulation allows some environmental parameters such as the temperature of the medium to be overcome, resulting in the possibility of cell sonoporation even at ambient temperature. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  15. Incubation pit analysis and calculation of the hydrodynamic impact pressure from the implosion of an acoustic cavitation bubble.

    PubMed

    Tzanakis, I; Eskin, D G; Georgoulas, A; Fytanidis, D K

    2014-03-01

    An experimental study to evaluate cavitation bubble dynamics is conducted. The aim is to predict the magnitude and statistical distribution of hydrodynamic impact pressure generated from the implosion of various individual acoustic cavitation bubbles near to a rigid boundary, considering geometrical features of the pitted area. A steel sample was subjected to cavitation impacts by an ultrasonic transducer with a 5mm diameter probe. The pitted surface was then examined using high-precision 3D optical interferometer techniques. Only the incubation period where surface is plastically deformed without material loss is taken into account. The exposure time was adjusted in the range of 3-60 s to avoid pit overlapping and a special procedure for pit analysis and characterisation was then followed. Moreover, a high-speed camera device was deployed to capture the implosion mechanisms of cavitation bubbles near to the surface. The geometrical characteristics of single incubation pits as well as pit clusters were studied and their deformation patterns were compared. Consequently, a reverse engineering approach was applied in order the hydrodynamic impact pressure from the implosion of an individual cavitation bubble to be determined. The characteristic parameters of the cavitation implosion process such as hydrodynamic impact pressure and liquid micro-jet impact velocity as well as the hydrodynamic severity of the cavitation impacts were quantified. It was found that the length of the hypotenuse of the orthographic projections from the center of the pit, which basically represents the deformed area of the pit, increases with the hydrodynamic impact aggressiveness in a linear rate. Majority of the hydrodynamic impacts were in the range of 0.4-1 GPa while the corresponding micro-jet velocities were found to be in the range of 200-700 m/s. Outcomes of this study, contribute to further understanding the cavitation intensity from the implosion of acoustically generated bubbles and could certainly represent a significant step towards developing more accurate cavitation models. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. The Effect of Fabric Position to the Distribution of Acoustic Pressure Field in Ultrasonic Bath

    NASA Astrophysics Data System (ADS)

    Gürses, B. O.; Özdemir, A. O.; Tonay, Ö.; Şener, M.; Perinçek, S.

    2017-10-01

    Nowadays, the use of ultrasonic energy in textile wet processes at industrial-scale is limited. It is largely due to the lack of understanding about design, operational and performance characteristics of the ultrasonic bath, suitable for textile treatments. In the context of this study, the effect of fabric position, as one of the design parameter, to the distribution of acoustic pressure field in ultrasonic bath was investigated. The ultrasonic bath in the size 20×30 cm2 with one transducer at frequency 40 kHz was used in experiments. The cotton fabric with 1 mm thickness was moved along vertical and horizontal directions of the ultrasonic bath. The acoustic field and cavitation volume density in the bath is analyzed by COMSOL Multiphysic. The cavitation volume density is calculated by comparing the pressure points in the bath with cavitation threshold pressure. Consequently, it was found that the position of the textile material in the ultrasonic bath is one of the most important factors to achieve the uniform and maximum acoustic cavitation field. So, it should be taken into consideration during the design of industrial-scale ultrasonic bath used in textile wet processes.

  17. Study on characteristics of single cavitation bubble considering condensation and evaporation of kerosene steam under ultrasonic vibration honing.

    PubMed

    Ye, Linzheng; Zhu, Xijing; Wang, Lujie; Guo, Ce

    2018-01-01

    Ultrasonic vibration honing technology is an effective means for materials difficult to machine, where cavitation occurs in grinding fluid under the action of ultrasound. To investigate the changes of single cavitation bubble characteristics in the grinding area and how honing parameters influence bubble characteristics, a dynamic model of single cavitation bubble in the ultrasonic vibration honing grinding area was established. The model was based on the bubble dynamics and considered the condensation and evaporation of kerosene steam and honing processing environment. The change rules of bubble radius, temperature, pressure and number of kerosene steam molecules inside the bubble were numerically simulated in the process of bubble moving. The results show that the condensation and evaporation of kerosene steam can help to explain the changes of temperature and pressure inside the bubble. Compared with ultrasonic vibration, the amplitude of bubble radius is greatly suppressed in the ultrasonic honing environment. However, the rate of movement of the bubble is faster. Meanwhile, the minimum values of pressure and temperature are larger, and the number of kerosene steam molecules is less. By studying the effect of honing factors on the movement of the cavitation bubble, it is found that honing pressure has a greater influence on bubble evolution characteristics, while rotation speed of honing head has a minor effect and the reciprocating speed of honing head has little impacts. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. AUGMENTATION OF MUSCLE BLOOD FLOW BY ULTRASOUND CAVITATION IS MEDIATED BY ATP AND PURINERGIC SIGNALING

    PubMed Central

    Belcik, J. Todd; Davidson, Brian P.; Xie, Aris; Wu, Melinda D.; Yadava, Mrinal; Qi, Yue; Liang, Sherry; Chon, Chae Ryung; Ammi, Azzdine Y.; Field, Joshua; Harmann, Leanne; Chilian, William M.; Linden, Joel; Lindner, Jonathan R.

    2017-01-01

    Background Augmentation of tissue blood flow by therapeutic ultrasound is thought to rely on convective shear. Microbubble contrast agents that undergo ultrasound-mediated cavitation markedly amplify these effects. We hypothesized that purinergic signalling is responsible for shear-dependent increases in muscle perfusion during therapeutic cavitation. Methods Unilateral exposure of the proximal hindlimb of mice (with or without ischemia produced by iliac ligation) to therapeutic ultrasound (1.3 MHz, mechanical index 1.3) was performed for ten minutes after intravenous injection of 2×108 lipid microbubbles. Microvascular perfusion was evaluated by low-power contrast ultrasound perfusion imaging. In vivo muscle ATP release and in vitro ATP release from endothelial cells or erythrocytes were assessed by a luciferin-luciferase assay. Purinergic signalling pathways were assessed by studying interventions that either (1) accelerated ATP degradation; (2) inhibited P2Y receptors, adenosine receptors, or KATP channels; or (3) inhibited downstream signalling pathways involving endothelial nitric oxide synthase (eNOS) or prostanoid production (indomethacin). Augmentation in muscle perfusion by ultrasound cavitation was assessed in a proof-of-concept clinical trial in 12 subjects with stable sickle cell disease (SCD). Results Therapeutic ultrasound cavitation increased muscle perfusion by 7-fold in normal mice, reversed tissue ischemia for up to 24 hrs in the murine model of peripheral artery disease, and doubled muscle perfusion in patients with SCD. Augmentation in flow extended well beyond the region of ultrasound exposure. Ultrasound cavitation produced a nearly 40-fold focal and sustained increase in ATP, the source of which included both endothelial cells and erythrocytes. Inhibitory studies indicated that ATP was a critical mediator of flow augmentation that acts primarily through either P2Y receptors or through adenosine produced by ectonucleotidase activity. Combined indomethacin and inhibition of eNOS abolished the effects of therapeutic ultrasound, indicating downstream signalling through both NO and prostaglandins. Conclusions Therapeutic ultrasound using microbubble cavitation to increase muscle perfusion relies on shear-dependent increases in ATP which can act through a diverse portfolio of purinergic signalling pathways. These events can reverse hindlimb ischemia in mice for >24 hours, and increase muscle blood flow in patients with sickle cell disease. Clinical Trial Registration NCT01566890 (https://clinicaltrials.gov/ct2/show/NCT01566890) PMID:28174191

  19. Occurrence of cyclophosphamide and ifosfamide in aqueous environment and their removal by biological and abiotic wastewater treatment processes.

    PubMed

    Česen, Marjeta; Kosjek, Tina; Laimou-Geraniou, Maria; Kompare, Boris; Širok, Brane; Lambropolou, Dimitra; Heath, Ester

    2015-09-15

    Cytostatic drug residues in the aqueous environment are of concern due to their possible adverse effects on non-target organisms. Here we report the occurrence and removal efficiency of cyclophosphamide (CP) and ifosfamide (IF) by biological and abiotic treatments including advanced oxidation processes (AOPs). Cyclophosphamide was detected in hospital wastewaters (14-22,000 ng L(-1)), wastewater treatment plant influents (19-27 ng L(-1)) and effluent (17 ng L(-1)), whereas IF was detected only in hospital wastewaters (48-6800 ng L(-1)). The highest removal efficiency during biological treatment (attached growth biomass in a flow through bioreactor) was 59 ± 15% and 35 ± 9.3% for CP and IF, respectively. Also reported are the removal efficiencies of both compounds from wastewater using hydrodynamic cavitation (HC), ozonation (O3) and/or UV, either individually or in combination with hydrogen peroxide (H2O2). Hydrodynamic cavitation did not remove CP and IF to any significant degree. The highest removal efficiencies: 99 ± 0.71% for CP and 94 ± 2.4% for IF, were achieved using UV/O3/H2O2 at 5 g L(-1) for 120 min. When combined with biological treatment, removal efficiencies were >99% for both compounds. This is the first report of combined biological and AOP treatment of CP and IF from wastewater with a removal efficiency >99%. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Cavitation effect of holmium laser pulse applied to ablation of hard tissue underwater.

    PubMed

    Lü, Tao; Xiao, Qing; Xia, Danqing; Ruan, Kai; Li, Zhengjia

    2010-01-01

    To overcome the inconsecutive drawback of shadow and schlieren photography, the complete dynamics of cavitation bubble oscillation or ablation products induced by a single holmium laser pulse [2.12 microm, 300 micros (FWHM)] transmitted in different core diameter (200, 400, and 600 microm) fibers is recorded by means of high-speed photography. Consecutive images from high-speed cameras can stand for the true and complete process of laser-water or laser-tissue interaction. Both laser pulse energy and fiber diameter determine cavitation bubble size, which further determines acoustic transient amplitudes. Based on the pictures taken by high-speed camera and scanned by an optical coherent microscopy (OCM) system, it is easily seen that the liquid layer at the distal end of the fiber plays an important role during the process of laser-tissue interaction, which can increase ablation efficiency, decrease heat side effects, and reduce cost.

  1. Decolorization of Acid Orange 7 by an electric field-assisted modified orifice plate hydrodynamic cavitation system: Optimization of operational parameters.

    PubMed

    Jung, Kyung-Won; Park, Dae-Seon; Hwang, Min-Jin; Ahn, Kyu-Hong

    2015-09-01

    In this study, the decolorization of Acid Orange 7 (AO-7) with intensified performance was obtained using hydrodynamic cavitation (HC) combined with an electric field (graphite electrodes). As a preliminary step, various HC systems were compared in terms of decolorization, and, among them, the electric field-assisted modified orifice plate HC (EFM-HC) system exhibited perfect decolorization performance within 40 min of reaction time. Interestingly, when H2O2 was injected into the EFM-HC system as an additional oxidant, the reactor performance gradually decreased as the dosing ratio increased; thus, the remaining experiments were performed without H2O2. Subsequently, an optimization process was conducted using response surface methodology with a Box-Behnken design. The inlet pressure, initial pH, applied voltage, and reaction time were chosen as operational key factors, while decolorization was selected as the response variable. The overall performance revealed that the selected parameters were either slightly interdependent, or had significant interactive effects on the decolorization. In the verification test, complete decolorization was observed under statistically optimized conditions. This study suggests that EFM-HC is a useful method for pretreatment of dye wastewater with positive economic and commercial benefits. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Cavitation inception by the backscattering of pressure waves from a bubble interface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Takahira, Hiroyuki, E-mail: takahira@me.osakafu-u.ac.jp; Ogasawara, Toshiyuki, E-mail: oga@me.osakafu-u.ac.jp; Mori, Naoto, E-mail: su101064@edu.osakafu-u.ac.jp

    2015-10-28

    The secondary cavitation that occurs by the backscattering of focused ultrasound from a primary cavitation bubble caused by the negative pressure part of the ultrasound (Maxwell, et al., 2011) might be useful for the energy exchange due to bubble oscillations in High Intensity Focused Ultrasound (HIFU). The present study is concerned with the cavitation inception by the backscattering of ultrasound from a bubble. In the present experiment, a laser-induced bubble which is generated by a pulsed focused laser beam with high intensity is utilized as a primary cavitation bubble. After generating the bubble, focused ultrasound is emitted to the bubble.more » The acoustic field and the bubble motion are observed with a high-speed video camera. It is confirmed that the secondary cavitation bubble clouds are generated by the backscattering from the laser-induced bubble. The growth of cavitation bubble clouds is analyzed with the image processing method. The experimental results show that the height and width of the bubble clouds grow in stepwise during their evolution. The direct numerical simulations are also conducted for the backscattering of incident pressure waves from a bubble in order to evaluate a pressure field near the bubble. It is shown that the ratio of a bubble collapse time t{sub 0} to a characteristic time of wave propagation t{sub S}, η = t{sub 0}/t{sub s}, is an important determinant for generating negative pressure region by backscattering. The minimum pressure location by the backscattering in simulations is in good agreement with the experiment.« less

  3. Impact of Cavitation, High Shear Stress and Air/Liquid Interfaces on Protein Aggregation.

    PubMed

    Duerkop, Mark; Berger, Eva; Dürauer, Astrid; Jungbauer, Alois

    2018-03-25

    The reported impact of shear stress on protein aggregation has been contradictory. At high shear rates, the occurrence of cavitation or entrapment of air is reasonable and their effects possibly misattributed to shear stress. Nine different proteins (α-lactalbumin, two antibodies, fibroblast growth factor 2, granulocyte colony stimulating factor [GCSF], green fluorescence protein [GFP], hemoglobin, human serum albumin, and lysozyme) are tested for their aggregation behavior on vapor/liquid interfaces generated by cavitation and compared it to the isolated effects of high shear stress and air/liquid interfaces generated by foaming. Cavitation induced the aggregation of GCSF by +68.9%, hemoglobin +4%, and human serum albumin +2.9%, compared to a control, whereas the other proteins do not aggregate. The protein aggregation behaviors of the different proteins at air/liquid interfaces are similar to cavitation, but the effect is more pronounced. Air-liquid interface induced the aggregation of GCSF by +94.5%, hemoglobin +35.5%, and human serum albumin (HSA) +31.1%. The results indicate that the sensitivity of a certain protein toward cavitation is very similar to air/liquid-induced aggregation. Hence, hydroxyl radicals cannot be seen as the driving force for protein aggregation when cavitation occurs. Further, high shear rates of up to 10 8  s -1 do not affect any of the tested proteins. Therefore, also within this study generated extremely high isolated shear rates cannot be considered to harm structural integrity when processing proteins. © 2018 The Authors. Biotechnology Journal Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  4. Ultrasound line-by-line scanning method of spatial-temporal active cavitation mapping for high-intensity focused ultrasound.

    PubMed

    Ding, Ting; Zhang, Siyuan; Fu, Quanyou; Xu, Zhian; Wan, Mingxi

    2014-01-01

    This paper presented an ultrasound line-by-line scanning method of spatial-temporal active cavitation mapping applicable in a liquid or liquid filled tissue cavities exposed by high-intensity focused ultrasound (HIFU). Scattered signals from cavitation bubbles were obtained in a scan line immediately after one HIFU exposure, and then there was a waiting time of 2 s long enough to make the liquid back to the original state. As this pattern extended, an image was built up by sequentially measuring a series of such lines. The acquisition of the beamformed radiofrequency (RF) signals for a scan line was synchronized with HIFU exposure. The duration of HIFU exposure, as well as the delay of the interrogating pulse relative to the moment while HIFU was turned off, could vary from microseconds to seconds. The feasibility of this method was demonstrated in tap-water and a tap-water filled cavity in the tissue-mimicking gelatin-agar phantom as capable of observing temporal evolutions of cavitation bubble cloud with temporal resolution of several microseconds, lateral and axial resolution of 0.50 mm and 0.29 mm respectively. The dissolution process of cavitation bubble cloud and spatial distribution affected by cavitation previously generated were also investigated. Although the application is limited by the requirement for a gassy fluid (e.g. tap water, etc.) that allows replenishment of nuclei between HIFU exposures, the technique may be a useful tool in spatial-temporal cavitation mapping for HIFU with high precision and resolution, providing a reference for clinical therapy. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. Surface modification of hydroturbine steel using friction stir processing

    NASA Astrophysics Data System (ADS)

    Grewal, H. S.; Arora, H. S.; Singh, H.; Agrawal, A.

    2013-03-01

    Friction stir processing (FSP) has proved to be a viable tool for enhancing the mechanical properties of materials, however, the major focus has been upon improving the bulk properties of light metals and their alloys. Hydroturbines are susceptible to damage owing to slurry and cavitation erosion. In this study, FSP of a commonly employed hydroturbine steel, 13Cr4Ni was undertaken. Microstructural characterization of the processed steel was conducted using optical microscopy (OM), scanning electron microscopy (SEM) equipped with energy dispersive spectroscopy (EDS), X-ray diffraction (XRD) and electron back scatter diffraction (EBSD) techniques. Mechanical characterization of the steel was undertaken in terms of microhardness and resistance to cavitation erosion (CE). FSP resulted in the refinement of the microstructure with reduction in grain size by a factor of 10. EBSD results confirmed the existence of submicron and ultrafine grained microstructure. The microhardness of the steel was found to enhance by 2.6 times after processing. The processed steel also showed 2.4 times higher resistance against cavitation erosion in comparison to unprocessed steel. The primary erosion mechanism for both the steels was identical in nature, with plastic deformation responsible for the loss of material.

  6. Field Experience with Lock Culvert Valves

    DTIC Science & Technology

    2013-12-01

    factors pertaining to valves such as the hoist loads, cavitation parameter, and effects of venting. To reduce the surge in the navigation channel...2 min 15 sec, filling-and-emptying valve opening time) ensures that adequate air is drawn into the culvert to cushion the cavitation implosions...shape can have adverse hydrodynamic loading consequences. The USACE, Mobile District (SAM) is in the process of designing replacement valves that are

  7. Cavitation studies in microgravity

    NASA Astrophysics Data System (ADS)

    Kobel, Philippe; Obreschkow, Danail; Farhat, Mohamed; Dorsaz, Nicolas; de Bosset, Aurele

    The hydrodynamic cavitation phenomenon is a major source of erosion for many industrial systems such as cryogenic pumps for rocket propulsion, fast ship propellers, hydraulic pipelines and turbines. Erosive processes are associated with liquid jets and shockwaves emission fol-lowing the cavity collapse. Yet, fundamental understanding of these processes requires further cavitation studies inside various geometries of liquid volumes, as the bubble dynamics strongly depends the surrounding pressure field. To this end, microgravity represents a unique platform to produce spherical fluid geometries and remove the hydrostatic pressure gradient induced by gravity. The goal of our first experiment (flown on ESA's parabolic flight campaigns 2005 and 2006) was to study single bubble dynamics inside large spherical water drops (having a radius between 8 and 13 mm) produced in microgravity. The water drops were created by a micro-pump that smoothly expelled the liquid through a custom-designed injector tube. Then, the cavitation bubble was generated through a fast electrical discharge between two electrodes immersed in the liquid from above. High-speed imaging allowed to analyze the implications of isolated finite volumes and spherical free surfaces on bubble evolution, liquid jets formation and shock wave dynamics. Of particular interest are the following results: (A) Bubble lifetimes are shorter than in extended liquid volumes, which could be explain by deriving novel corrective terms to the Rayleigh-Plesset equation. (B) Transient crowds of micro-bubbles (smaller than 1mm) appeared at the instants of shockwaves emission. A comparison between high-speed visualizations and 3D N-particle simulations of a shock front inside a liquid sphere reveals that focus zones within the drop lead to a significantly increased density of induced cavitation. Considering shock wave crossing and focusing may hence prove crucially useful to understand the important process of cavitation erosion. The aim of our future microgravity experiment is to assess the direct effects of gravity on cavitation bubble collapse through a comparison of single cavitation bubbles collapsing in mi-crogravity, normal gravity, and hypergravity. In particular, we shall investigate the shape of the bubble in its final collapse stage and the amount of energy dissipated in the dominant collapse channels, such as liquid jet, shock wave, and rebound bubble. The highly spherical bubbles will be produced via a point-like plasma generated by a high power laser beam. One major hypothesis that we will test is an increase in shock wave energy with decreasing gravity as a consequence of the higher final sphericity and suppression of liquid jets. To support this, we introduce an analytical model for the gravity-perturbed asymmetric collapse of spherical bubbles, and demonstrate that all initially spherical bubbles develop a gravity-related vertical jet along their collapse.

  8. Influence of hydrodynamic cavitation on the rheological properties and microstructure of formulated Greek-style yogurts.

    PubMed

    Meletharayil, G H; Metzger, L E; Patel, Hasmukh A

    2016-11-01

    With limited applications of acid whey generated during the manufacture of Greek yogurts, an alternate processing technology to sidestep the dewheying process was developed. Milk protein concentrate (MPC) and carbon dioxide-treated milk protein concentrate (TMPC) were used as sources of protein to fortify skim milk to 9% (wt/wt) protein for the manufacture of Greek-style yogurts (GSY). The GSY bases were inoculated and fermented with frozen direct vat set yogurt culture to a pH of 4.6. Owing to the difference in buffering of MPC and TMPC, GSY with TMPC and MPC exhibited different acidification kinetics, with GSY containing TMPC having a lower fermentation time. The GSY with TMPC had a titratable acidity of 1.45% lactic acid and was comparable to acidity of commercial Greek yogurt (CGY). Hydrodynamic cavitation at 4 different rotor speeds (0, 15, 30, and 60 Hz) as a postfermentation tool reduced the consistency coefficient (K) of GSY containing TMPC from 79.4 Pa·s n at 0 Hz to 17.59 Pa·s n at 60 Hz. Similarly for GSY containing MPC, K values decreased from 165.74 Pa·s n at 0 Hz to 53.04 Pa·s n at 60 Hz. The apparent viscosity (η 100 ) was 0.25 Pa·s for GSY containing TMPC and 0.66 Pa·s for GSY containing MPC at 60 Hz. The CGY had a η 100 value of 0.74 Pa·s. Small amplitude rheological analysis performed on GSY indicated a loss of elastic modulus dependency on frequency caused by the breakdown of protein interactions with increasing cavitator rotor speeds. A steady decrease in hardness and adhesiveness values of GSY was observed with increasing cavitational intensities. Numbers of grains with a perimeter of >1mm of cavitated GSY with TMPC and MPC were 35 and 13 grains/g of yogurt, respectively, and were lower than 293 grains/g observed in CGY. The water-holding capacity of GSY was higher than that observed for a commercial strained Greek yogurt. The ability to scale up the process of hydrodynamic cavitation industrially, and the ease of controlling events of cavitation that can influence final textural properties of the product, make this technology promising for large-scale industrial application. Overall, the current set of experiments employed in the manufacture of GSY, which included the use of TMPC as a protein source in conjunction with hydrodynamic cavitation, could help achieve comparable titratable acidity values, rheological properties, and microstructure to that of a commercial strained Greek yogurt. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  9. A New Unsteady Model for Dense Cloud Cavitation in Cryogenic Fluids

    NASA Technical Reports Server (NTRS)

    Hosangadi, A.; Ahuja, V.

    2005-01-01

    A new unsteady, cavitation model is presented wherein the phase change process (bubble growth/collapse) is coupled to the acoustic field in a cryogenic fluid. It predicts the number density and radius of bubbles in vapor clouds by tracking both the aggregate surface area and volume fraction of the cloud. Hence, formulations for the dynamics of individual bubbles (e.g. Rayleigh-Plesset equation) may be integrated within the macroscopic context of a dense vapor cloud i.e. a cloud that occupies a significant fraction of available volume and contains numerous bubbles. This formulation has been implemented within the CRUNCH CFD, which has a compressible real fluid formulation, a multi-element, unstructured grid framework, and has been validated extensively for liquid rocket turbopump inducers. Detailed unsteady simulations of a cavitating ogive in liquid nitrogen are presented where time-averaged mean cavity pressure and temperature depressions due to cavitation are compared with experimental data. The model also provides the spatial and temporal history of the bubble size distribution in the vapor clouds that are shed, an important physical parameter that is difficult to measure experimentally and is a significant advancement in the modeling of dense cloud cavitation.

  10. Optimization of biodiesel production in a hydrodynamic cavitation reactor using used frying oil.

    PubMed

    Ghayal, Dyneshwar; Pandit, Aniruddha B; Rathod, Virendra K

    2013-01-01

    The present work demonstrates the application of a hydrodynamic cavitation reactor for the synthesis of biodiesel with used frying oil as a feedstock. The synthesis involved the transesterification of used frying oil (UFO) with methanol in the presence of potassium hydroxide as a catalyst. The effect of geometry and upstream pressure of a cavitating orifice plate on the rate of transesterification reaction has been studied. It is observed that the micro level turbulence created by hydrodynamic cavitation somewhat overcomes the mass transfer limitations for triphasic transesterification reaction. The significant effects of upstream pressure on the rate of formation of methyl esters have been seen. It has been observed that flow geometry of orifice plate plays a crucial role in process intensification. With an optimized plate geometry of 2mm hole diameter and 25 holes, more than 95% of triglycerides have been converted to methyl esters in 10 min of reaction time with cavitational yield of 1.28 × 10(-3) (Grams of methyl esters produced per Joule of energy supplied). The potential of UFO to produce good quality methyl esters has been demonstrated. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Cavitation during wire brushing

    NASA Astrophysics Data System (ADS)

    Li, Bo; Zou, Jun; Ji, Chen

    2016-11-01

    In our daily life, brush is often used to scrub the surface of objects, for example, teeth, pots, shoes, pool, etc. And cleaning rust and stripping paint are accomplished using wire brush. Wire brushes also can be used to clean the teeth for large animals, such as horses, crocodiles. By observing brushing process in water, we capture the cavitation phenomenon on the track of moving brush wire. It shows that the cavitation also can affect the surface. In order to take clear and entire pictures of cavity, a simplified model of one stainless steel wire brushing a boss is adopted in our experiment. A transparent organic tank filled with deionized water is used as a view box. And a high speed video camera is used to record the sequences. In experiment, ambient pressure is atmospheric pressure and deionized water temperature is kept at home temperature. An obvious beautiful flabellate cavity zone appears behind the moving steel wire. The fluctuation of pressure near cavity is recorded by a hydrophone. More movies and pictures are used to show the behaviors of cavitation bubble following a restoring wire. Beautiful tracking cavitation bubble cluster is captured and recorded to show.

  12. Counterbalancing the use of ultrasound contrast agents by a cavitation-regulated system.

    PubMed

    Desjouy, C; Fouqueray, M; Lo, C W; Muleki Seya, P; Lee, J L; Bera, J C; Chen, W S; Inserra, C

    2015-09-01

    The stochastic behavior of cavitation can lead to major problems of initiation and maintenance of cavitation during sonication, responsible of poor reproducibility of US-induced bioeffects in the context of sonoporation for instance. To overcome these disadvantages, the injection of ultrasound contrast agents as cavitation nuclei ensures fast initiation and lower acoustic intensities required for cavitation activity. More recently, regulated-cavitation devices based on the real-time modulation of the applied acoustic intensity have shown their potential to maintain a stable cavitation state during an ultrasonic shot, in continuous or pulsed wave conditions. In this paper is investigated the interest, in terms of cavitation activity, of using such regulated-cavitation device or injecting ultrasound contrast agents in the sonicated medium. When using fixed applied acoustic intensity, results showed that introducing ultrasound contrast agents increases reproducibility of cavitation activity (coefficient of variation 62% and 22% without and with UCA, respectively). Moreover, the use of the regulated-cavitation device ensures a given cavitation activity (coefficient of variation less 0.4% in presence of UCAs or not). This highlights the interest of controlling cavitation over time to free cavitation-based application from the use of UCAs. Interestingly, during a one minute sonication, while ultrasound contrast agents progressively disappear, the regulated-cavitation device counterbalance their destruction to sustain a stable inertial cavitation activity. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Unstable 3D phenomena: Dynamic interactions of a cavitation bubble and Richtmyer-Meshkov unstable divot

    NASA Astrophysics Data System (ADS)

    Buttler, William; Renner, Dru; Morris, Chris; Manzanares, Ruben; Heidemann, Joel; Kalas, Ryan; Llobet, Anna; Martinez, John; Payton, Jeremy; Saunders, Andy; Schmidt, Derek; Tainter, Amy; Vincent, Samuel; Vogan-McNeil, Wendy

    2017-06-01

    We radiographically explore a shock-induced Sn cavitation bubble as it interacts with a transverse cavitation wave caused by a Richtmyer-Meshkov unstable spike from a divot. The cavitation bubble forms as two shockwaves collide under the divot, as the shockwaves release to ambient pressure at the surface. The divot inverts and unstably grows, as expected and predicted, but the release waves that form the cavitation bubble reflect from and constrain the cavitation wave growth. As the cavitation wave grows it pierces the cavitation bubble, deflating it onto the unstable transverse cavitation wave.

  14. Cavitation study of a pump-turbine at turbine mode with critical cavitation coefficient condition

    NASA Astrophysics Data System (ADS)

    Wang, J.; Yang, D.; Xu, J. W.; Liu, J. T.; Jiao, L.

    2016-05-01

    To study the cavitation phenomenon of a pump-turbine at turbine mode when it ran at the critical cavitation coefficient condition, a high-head model pump-turbine was disperse using hexahedron grid. Three dimensional, steady cavitating flow was numerically studied using SST k-ω model. It is confirmed that ZGB cavitation model and SST k-ω model are useful ways to study the two-phase cavitation flow in pump-turbine. Mass flow inlet and pressure outlet were specified at the casing inlet and draft tube outlet, respectively. The static pressure was set according to the cavitation coefficient. The steady cavitating flows at critical cavitation coefficient condition were analysed. The cavitation area in the runner was investigated. It was found that the pressure of the suction on the blade surface was decreasing gradually with the decrease of the cavitation coefficient. In addition, the vortex flow in the draft tube was observed at the critical cavitation coefficient. It was found that the vortex flow appeared at the center of the draft tube inlet with the decreasing of the cavitation coefficient. Compared with the experimental data, the simulation results show reasonable agreement with the experimental data.

  15. Cavitation guide for control valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tullis, J.P.

    1993-04-01

    This guide teaches the basic fundamentals of cavitation to provide the reader with an understanding of what causes cavitation, when it occurs, and the potential problems cavitation can cause to a valve and piping system. The document provides guidelines for understanding how to reduce the cavitation and/or select control valves for a cavitating system. The guide provides a method for predicting the cavitation intensity of control valves, and how the effect of cavitation on a system will vary with valve type, valve function, valve size, operating pressure, duration of operation and details of the piping installation. The guide defines sixmore » cavitation limits identifying cavitation intensities ranging from inception to the maximum intensity possible. The intensity of the cavitation at each limit Is described, including a brief discussion of how each level of cavitation influences the valve and system. Examples are included to demonstrate how to apply the method, including making both size and pressure scale effects corrections. Methods of controlling cavitation are discussed providing information on various techniques which can be used to design a new system or modify an existing one so it can operate at a desired level of cavitation.« less

  16. Hemolytic potential of hydrodynamic cavitation.

    PubMed

    Chambers, S D; Bartlett, R H; Ceccio, S L

    2000-08-01

    The purpose of this study was to determine the hemolytic potentials of discrete bubble cavitation and attached cavitation. To generate controlled cavitation events, a venturigeometry hydrodynamic device, called a Cavitation Susceptibility Meter (CSM), was constructed. A comparison between the hemolytic potential of discrete bubble cavitation and attached cavitation was investigated with a single-pass flow apparatus and a recirculating flow apparatus, both utilizing the CSM. An analytical model, based on spherical bubble dynamics, was developed for predicting the hemolysis caused by discrete bubble cavitation. Experimentally, discrete bubble cavitation did not correlate with a measurable increase in plasma-free hemoglobin (PFHb), as predicted by the analytical model. However, attached cavitation did result in significant PFHb generation. The rate of PFHb generation scaled inversely with the Cavitation number at a constant flow rate, suggesting that the size of the attached cavity was the dominant hemolytic factor.

  17. Post-fire Tree Mortality: Heating Increases Vulnerability to Cavitation in Longleaf Pine Branches

    NASA Astrophysics Data System (ADS)

    Lodge, A.; Kavanagh, K.; Dickinson, M. B.

    2016-12-01

    Tree mortality following wild and prescribed fires is of interest to both researchers and land managers. While some models exist that can predict mortality following fires, process-based models that incorporate physiological mechanisms of mortality are still being developed and improved. Delayed post-fire tree mortality has recently received increased attention, in part due to an increased use of prescribed fire as a restoration and management tool. One hypothesized mechanism of delayed mortality in trees is disruption of water transport in xylem due to exposure to the heat plume of a fire. This heat plume rapidly increases the vapor pressure deficit in the tree canopy, quickly increasing the tension on the water held in the xylem and leaves, potentially leading to cavitation. Cavitated xylem conduits can no longer transport water, eventually leading to tree death. We conducted a laboratory experiment examining whether heating stems increases their vulnerability to cavitation. We placed longleaf pine (Pinus palustris) branches in a water bath at sub-lethal temperatures (<60°C) and applied pressure in a cavitation chamber to simulate a range of xylem tension levels that may occur during fire. Percent loss of conductivity was measured following cavitation induced by various levels of applied pressure. When we compared the resulting vulnerability curves of heated branches to those of branches pressurized at room temperature, we observed increased vulnerability to cavitation in the heated samples especially at lower pressures. P50, or the pressure at which 50% of conductivity has been lost, decreased by 18% on branches heated to approximately 54°C. This suggests that stems heated during fires may be more vulnerable to cavitation, and provides some support for hydraulic disruption as a mechanism for post-fire tree mortality. Continued advancement in understanding of the mechanisms leading to delayed mortality will improve models predicting tree mortality.

  18. Cellular High-Energy Cavitation Trauma - Description of a Novel In Vitro Trauma Model in Three Different Cell Types.

    PubMed

    Cao, Yuli; Risling, Mårten; Malm, Elisabeth; Sondén, Anders; Bolling, Magnus Frödin; Sköld, Mattias K

    2016-01-01

    The mechanisms involved in traumatic brain injury have yet to be fully characterized. One mechanism that, especially in high-energy trauma, could be of importance is cavitation. Cavitation can be described as a process of vaporization, bubble generation, and bubble implosion as a result of a decrease and subsequent increase in pressure. Cavitation as an injury mechanism is difficult to visualize and model due to its short duration and limited spatial distribution. One strategy to analyze the cellular response of cavitation is to employ suitable in vitro models. The flyer-plate model is an in vitro high-energy trauma model that includes cavitation as a trauma mechanism. A copper fragment is accelerated by means of a laser, hits the bottom of a cell culture well causing cavitation, and shock waves inside the well and cell medium. We have found the flyer-plate model to be efficient, reproducible, and easy to control. In this study, we have used the model to analyze the cellular response to microcavitation in SH-SY5Y neuroblastoma, Caco-2, and C6 glioma cell lines. Mitotic activity in neuroblastoma and glioma was investigated with BrdU staining, and cell numbers were calculated using automated time-lapse imaging. We found variations between cell types and between different zones surrounding the lesion with these methods. It was also shown that the injured cell cultures released S-100B in a dose-dependent manner. Using gene expression microarray, a number of gene families of potential interest were found to be strongly, but differently regulated in neuroblastoma and glioma at 24 h post trauma. The data from the gene expression arrays may be used to identify new candidates for biomarkers in cavitation trauma. We conclude that our model is useful for studies of trauma in vitro and that it could be applied in future treatment studies.

  19. High speed imaging of bubble clouds generated in pulsed ultrasound cavitational therapy--histotripsy.

    PubMed

    Xu, Zhen; Raghavan, Mekhala; Hall, Timothy L; Chang, Ching-Wei; Mycek, Mary-Ann; Fowlkes, J Brian; Cain, Charles A

    2007-10-01

    Our recent studies have demonstrated that mechanical fractionation of tissue structure with sharply demarcated boundaries can be achieved using short (< 20 micros), high intensity ultrasound pulses delivered at low duty cycles. We have called this technique histotripsy. Histotripsy has potential clinical applications where noninvasive tissue fractionation and/or tissue removal are desired. The primary mechanism of histotripsy is thought to be acoustic cavitation, which is supported by a temporally changing acoustic backscatter observed during the histotripsy process. In this paper, a fast-gated digital camera was used to image the hypothesized cavitating bubble cloud generated by histotripsy pulses. The bubble cloud was produced at a tissue-water interface and inside an optically transparent gelatin phantom which mimics bulk tissue. The imaging shows the following: (1) Initiation of a temporally changing acoustic backscatter was due to the formation of a bubble cloud; (2) The pressure threshold to generate a bubble cloud was lower at a tissue-fluid interface than inside bulk tissue; and (3) at higher pulse pressure, the bubble cloud lasted longer and grew larger. The results add further support to the hypothesis that the histotripsy process is due to a cavitating bubble cloud and may provide insight into the sharp boundaries of histotripsy lesions.

  20. High Speed Imaging of Bubble Clouds Generated in Pulsed Ultrasound Cavitational Therapy—Histotripsy

    PubMed Central

    Xu, Zhen; Raghavan, Mekhala; Hall, Timothy L.; Chang, Ching-Wei; Mycek, Mary-Ann; Fowlkes, J. Brian; Cain, Charles A.

    2009-01-01

    Our recent studies have demonstrated that mechanical fractionation of tissue structure with sharply demarcated boundaries can be achieved using short (<20 μs), high intensity ultrasound pulses delivered at low duty cycles. We have called this technique histotripsy. Histotripsy has potential clinical applications where noninvasive tissue fractionation and/or tissue removal are desired. The primary mechanism of histotripsy is thought to be acoustic cavitation, which is supported by a temporally changing acoustic backscatter observed during the histotripsy process. In this paper, a fast-gated digital camera was used to image the hypothesized cavitating bubble cloud generated by histotripsy pulses. The bubble cloud was produced at a tissue-water interface and inside an optically transparent gelatin phantom which mimics bulk tissue. The imaging shows the following: 1) Initiation of a temporally changing acoustic backscatter was due to the formation of a bubble cloud; 2) The pressure threshold to generate a bubble cloud was lower at a tissue-fluid interface than inside bulk tissue; and 3) at higher pulse pressure, the bubble cloud lasted longer and grew larger. The results add further support to the hypothesis that the histotripsy process is due to a cavitating bubble cloud and may provide insight into the sharp boundaries of histotripsy lesions. PMID:18019247

  1. PREFACE: 9th International Symposium on Cavitation (CAV2015)

    NASA Astrophysics Data System (ADS)

    Farhat, M.; Müller, A.

    2015-12-01

    It is our pleasure and privilege to welcome all the participants of the 9th International Symposium on Cavitation (CAV2015) to Lausanne. Since its initiation in 1986 in Sendai, Japan, the CAV symposium has grown to become the world's foremost event dedicated to cavitation. Hosted by EPFL (Ecole Polytechnique Fédérale de Lausanne) and staged at the SwissTech Convention Center, CAV2015 is a unique opportunity to exchange with leading scientists and industry experts about the latest advances in theoretical modelling, numerical simulation and experimentation related to cavitation phenomena with a special emphasis on practical applications. The topics covered by CAV2015 include cavitation in ¬fluid machinery and fuel systems, bubble dynamics, cavitation erosion, advanced numerical simulation, sonochemistery, biomedicine and experimental techniques. CAV2015 will also host an exhibition of leading providers of state of the art measurement equipment, including high-speed imaging systems, non-intrusive velocimetry, pressure sensors, as well as numerical solvers. We have accepted over 190 papers, which will be presented in four parallel sessions. The proceedings will appear in the open access Journal of Physics: Conference Series (JPCS), which is part of the IOP Conference Series. All published papers are fully citable and upon publication will be free to download in perpetuity. We would like to thank all the reviewers for their great help during the selection process. We will also propose six plenary speakers to highlight cavitation issues in different fields. Finally, we would like to warmly thank our sponsors for their valuable support and the local Organizing Committee for the efforts in setting up this important event. We look forward to seeing you in Lausanne!

  2. Towards numerical prediction of cavitation erosion.

    PubMed

    Fivel, Marc; Franc, Jean-Pierre; Chandra Roy, Samir

    2015-10-06

    This paper is intended to provide a potential basis for a numerical prediction of cavitation erosion damage. The proposed method can be divided into two steps. The first step consists in determining the loading conditions due to cavitation bubble collapses. It is shown that individual pits observed on highly polished metallic samples exposed to cavitation for a relatively small time can be considered as the signature of bubble collapse. By combining pitting tests with an inverse finite-element modelling (FEM) of the material response to a representative impact load, loading conditions can be derived for each individual bubble collapse in terms of stress amplitude (in gigapascals) and radial extent (in micrometres). This step requires characterizing as accurately as possible the properties of the material exposed to cavitation. This characterization should include the effect of strain rate, which is known to be high in cavitation erosion (typically of the order of several thousands s(-1)). Nanoindentation techniques as well as compressive tests at high strain rate using, for example, a split Hopkinson pressure bar test system may be used. The second step consists in developing an FEM approach to simulate the material response to the repetitive impact loads determined in step 1. This includes a detailed analysis of the hardening process (isotropic versus kinematic) in order to properly account for fatigue as well as the development of a suitable model of material damage and failure to account for mass loss. Although the whole method is not yet fully operational, promising results are presented that show that such a numerical method might be, in the long term, an alternative to correlative techniques used so far for cavitation erosion prediction.

  3. Towards numerical prediction of cavitation erosion

    PubMed Central

    Fivel, Marc; Franc, Jean-Pierre; Chandra Roy, Samir

    2015-01-01

    This paper is intended to provide a potential basis for a numerical prediction of cavitation erosion damage. The proposed method can be divided into two steps. The first step consists in determining the loading conditions due to cavitation bubble collapses. It is shown that individual pits observed on highly polished metallic samples exposed to cavitation for a relatively small time can be considered as the signature of bubble collapse. By combining pitting tests with an inverse finite-element modelling (FEM) of the material response to a representative impact load, loading conditions can be derived for each individual bubble collapse in terms of stress amplitude (in gigapascals) and radial extent (in micrometres). This step requires characterizing as accurately as possible the properties of the material exposed to cavitation. This characterization should include the effect of strain rate, which is known to be high in cavitation erosion (typically of the order of several thousands s−1). Nanoindentation techniques as well as compressive tests at high strain rate using, for example, a split Hopkinson pressure bar test system may be used. The second step consists in developing an FEM approach to simulate the material response to the repetitive impact loads determined in step 1. This includes a detailed analysis of the hardening process (isotropic versus kinematic) in order to properly account for fatigue as well as the development of a suitable model of material damage and failure to account for mass loss. Although the whole method is not yet fully operational, promising results are presented that show that such a numerical method might be, in the long term, an alternative to correlative techniques used so far for cavitation erosion prediction. PMID:26442139

  4. Visualization of fluid turbulence and acoustic cavitation during phacoemulsification.

    PubMed

    Tognetto, Daniele; Sanguinetti, Giorgia; Sirotti, Paolo; Brezar, Edoardo; Ravalico, Giuseppe

    2005-02-01

    To describe a technique for visualizing fluid turbulence and cavitational energy created by ultrasonic phaco tips. University Eye Clinic of Trieste, Trieste, Italy. Generation of cavitational energy by the phaco tip was visualized using an optical test bench comprising several components. The technique uses a telescope system to expand a laser light source into a coherent, collimated beam of light with a diameter of approximately 50.0 mm. The expanded laser beam shines on the test tube containing the tip activated in a medium of water or ophthalmic viscosurgical device (OVD). Two precision optical collimators complete the optical test bench and form the system used to focus data onto a charge-coupled device television camera connected to a recorder. Images of irrigation, irrigation combined with aspiration, irrigation/aspiration, and phacosonication were obtained with the tip immersed in a tube containing water or OVD. Optical image processing enabled acoustic cavitation to be visualized during phacosonication. The system is a possible means of evaluating a single phaco apparatus power setting and comparing phaco machines and techniques.

  5. Observation of chemiluminescence induced by hydrodynamic cavitation in microchannels.

    PubMed

    Podbevsek, D; Colombet, D; Ledoux, G; Ayela, F

    2018-05-01

    We have performed hydrodynamic cavitation experiments with an aqueous luminol solution as the working fluid. Light emission, together with the high frequency noise which characterizes cavitation, was emitted by the two-phase flow, whereas no light emission from luminol was recorded in the single phase liquid flow. Light emission occurs downstream transparent microdiaphragms. The maximum level of the recorded signal was around 180 photons per second with flow rates of 380 µl/s, that corresponds to a real order of magnitude of the chemiluminescence of 75,000 photons per second. The yield of emitted photons increases linearly with the pressure drop, which is proportional to the square of the total flow rate. Chemiluminescence of luminol is a direct and a quantitative demonstration of the presence of OH hydroxyl radicals created by hydrodynamic cavitation. The presented method could be a key to optimize channel geometry for processes where radical production is essential. Copyright © 2018 Elsevier B.V. All rights reserved.

  6. Mineralisation of 2,4-dichlorophenoxyacetic acid by acoustic or hydrodynamic cavitation in conjunction with the advanced Fenton process.

    PubMed

    Bremner, David H; Carlo, Stefano Di; Chakinala, Anand G; Cravotto, Giancarlo

    2008-04-01

    The mineralisation of 2,4-dichlorophenoxyacetic acid (2,4-D) in the presence of zero-valent iron and hydrogen peroxide (the advanced Fenton process--AFP) whilst being subjected to acoustic or hydrodynamic cavitation is reported. If the reaction is merely stirred then there is 57% removal of TOC whilst on irradiation the figure is 64% although the latter reaction is more rapid. Use of ultrasound alone results in only 11% TOC removal in 60 min of treatment time. Addition of iron powder marginally enhances the extent of degradation but an appreciable increase is observed in the presence of hydrogen peroxide which acts as a source for hydroxyl radicals by Fenton chemistry as well as by dissociation in the presence of ultrasound. The use of hydrodynamic cavitation in conjunction with the advanced Fenton process has also been found to be a useful tool for continuous remediation of water contaminated with 2,4-D. After 20 min of treatment the residual TOC is reduced to 30% and this probably represents the remaining highly recalcitrant small organic molecules.

  7. AUGMENTATION OF LIMB PERFUSION AND REVERSAL OF TISSUE ISCHEMIA PRODUCED BY ULTRASOUND-MEDIATED MICROBUBBLE CAVITATION

    PubMed Central

    Belcik, J. Todd; Mott, Brian H.; Xie, Aris; Zhao, Yan; Kim, Sajeevani; Lindner, Nathan J.; Ammi, Azzdine; Linden, Joel M.; Lindner, Jonathan R.

    2015-01-01

    Background Ultrasound can increase tissue blood flow in part through the intravascular shear produced by oscillatory pressure fluctuations. We hypothesized that ultrasound-mediated increases in perfusion can be augmented by microbubble contrast agents that undergo ultrasound-mediated cavitation, and sought to characterize the biologic mediators. Methods and Results Contrast ultrasound perfusion imaging of hindlimb skeletal muscle and femoral artery diameter measurement were performed in non-ischemic mice after unilateral 10 min exposure to intermittent ultrasound alone (mechanical index [MI] 0.6 or 1.3) or ultrasound with lipid microbubbles (2×108 I.V.). Studies were also performed after inhibiting shear- or pressure-dependent vasodilator pathways, and in mice with hindlimb ischemia. Ultrasound alone produced a 2-fold increase (p<0.05) in muscle perfusion regardless of ultrasound power. Ultrasound-mediated augmentation in flow was greater with microbubbles (3-fold and 10-fold higher than control for MI 0.6 and 1.3, respectively; p<0.05), as was femoral artery dilation. Inhibition of endothelial nitric oxide synthase (eNOS) attenuated flow augmentation produced by ultrasound and microbubbles by 70% (p<0.01), whereas inhibition of adenosine-A2a receptors and epoxyeicosatrienoic acids had minimal effect. Limb nitric oxide (NO) production and muscle phospho-eNOS increased in a stepwise fashion by ultrasound and ultrasound with microbubbles. In mice with unilateral hindlimb ischemia (40–50% reduction in flow), ultrasound (MI 1.3) with microbubbles increased perfusion by 2-fold to a degree that was greater than the control non-ischemic limb. Conclusions Increases in muscle blood flow during high-power ultrasound are markedly amplified by the intravascular presence of microbubbles and can reverse tissue ischemia. These effects are most likely mediated by cavitation-related increases in shear and activation of eNOS. PMID:25834183

  8. Acoustic and visual characteristics of cavitation induced by mechanical heart valves.

    PubMed

    Sohn, Kwanghyun; Manning, Keefe B; Fontaine, Arnold A; Tarbell, John M; Deutsch, Steven

    2005-07-01

    A sudden pressure drop and recovery can induce cavitation in liquids. Mechanical heart valves (MHVs) generate such a pressure drop at closure, and cavitation generation around MHVs has been demonstrated many times. Cavitation is suspected as being a cause of blood and valve material damage. In this in-vitro experiment, visual images and acoustic signals associated with MHV cavitation were studied to reveal cavitation characteristics. Björk-Shiley Convex-Concave valves, one with a pyrolytic carbon occluder and one with a Delrin occluder, were installed in a single-shot valve chamber. Cavitation intensity was controlled by load (dP/dt) and air content of water. The acoustic signal was measured using a hydrophone and visual images recorded with a high-speed digital camera system. Cavitation images showed that 10 ppm water rarely developed cavitation, unlike the 16 ppm water. A distinct peak pressure was observed at cavitation collapse that was a good indicator of MHV cavitation intensity. The average of the peak pressures revealed that cavitation intensity increased faster with increasing load for the 16 ppm water. The use of the peak pressure may be the preferred method for correlating cavitation intensity in structures for which the separation of valve closure noise and cavitation signal is difficult, as for the valves studied here.

  9. Prediction of Cavitation Depth in an Al-Cu Alloy Melt with Bubble Characteristics Based on Synchrotron X-ray Radiography

    NASA Astrophysics Data System (ADS)

    Huang, Haijun; Shu, Da; Fu, Yanan; Zhu, Guoliang; Wang, Donghong; Dong, Anping; Sun, Baode

    2018-06-01

    The size of cavitation region is a key parameter to estimate the metallurgical effect of ultrasonic melt treatment (UST) on preferential structure refinement. We present a simple numerical model to predict the characteristic length of the cavitation region, termed cavitation depth, in a metal melt. The model is based on wave propagation with acoustic attenuation caused by cavitation bubbles which are dependent on bubble characteristics and ultrasonic intensity. In situ synchrotron X-ray imaging of cavitation bubbles has been made to quantitatively measure the size of cavitation region and volume fraction and size distribution of cavitation bubbles in an Al-Cu melt. The results show that cavitation bubbles maintain a log-normal size distribution, and the volume fraction of cavitation bubbles obeys a tanh function with the applied ultrasonic intensity. Using the experimental values of bubble characteristics as input, the predicted cavitation depth agrees well with observations except for a slight deviation at higher acoustic intensities. Further analysis shows that the increase of bubble volume and bubble size both leads to higher attenuation by cavitation bubbles, and hence, smaller cavitation depth. The current model offers a guideline to implement UST, especially for structural refinement.

  10. Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles

    NASA Astrophysics Data System (ADS)

    Burgess, M. T.; Apostolakis, I.; Konofagou, E. E.

    2018-03-01

    Image-guided monitoring of microbubble-based focused ultrasound (FUS) therapies relies on the accurate localization of FUS-stimulated microbubble activity (i.e. acoustic cavitation). Passive cavitation imaging with ultrasound arrays can achieve this, but with insufficient spatial resolution. In this study, we address this limitation and perform high-resolution monitoring of acoustic cavitation-mediated blood-brain barrier (BBB) opening with a new technique called power cavitation imaging. By synchronizing the FUS transmit and passive receive acquisition, high-resolution passive cavitation imaging was achieved by using delay and sum beamforming with absolute time delays. Since the axial image resolution is now dependent on the duration of the received acoustic cavitation emission, short pulses of FUS were used to limit its duration. Image sets were acquired at high-frame rates for calculation of power cavitation images analogous to power Doppler imaging. Power cavitation imaging displays the mean intensity of acoustic cavitation over time and was correlated with areas of acoustic cavitation-induced BBB opening. Power cavitation-guided BBB opening with FUS could constitute a standalone system that may not require MRI guidance during the procedure. The same technique can be used for other acoustic cavitation-based FUS therapies, for both safety and guidance.

  11. Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles.

    PubMed

    Burgess, M T; Apostolakis, I; Konofagou, E E

    2018-03-15

    Image-guided monitoring of microbubble-based focused ultrasound (FUS) therapies relies on the accurate localization of FUS-stimulated microbubble activity (i.e. acoustic cavitation). Passive cavitation imaging with ultrasound arrays can achieve this, but with insufficient spatial resolution. In this study, we address this limitation and perform high-resolution monitoring of acoustic cavitation-mediated blood-brain barrier (BBB) opening with a new technique called power cavitation imaging. By synchronizing the FUS transmit and passive receive acquisition, high-resolution passive cavitation imaging was achieved by using delay and sum beamforming with absolute time delays. Since the axial image resolution is now dependent on the duration of the received acoustic cavitation emission, short pulses of FUS were used to limit its duration. Image sets were acquired at high-frame rates for calculation of power cavitation images analogous to power Doppler imaging. Power cavitation imaging displays the mean intensity of acoustic cavitation over time and was correlated with areas of acoustic cavitation-induced BBB opening. Power cavitation-guided BBB opening with FUS could constitute a standalone system that may not require MRI guidance during the procedure. The same technique can be used for other acoustic cavitation-based FUS therapies, for both safety and guidance.

  12. Prediction of Cavitation Depth in an Al-Cu Alloy Melt with Bubble Characteristics Based on Synchrotron X-ray Radiography

    NASA Astrophysics Data System (ADS)

    Huang, Haijun; Shu, Da; Fu, Yanan; Zhu, Guoliang; Wang, Donghong; Dong, Anping; Sun, Baode

    2018-04-01

    The size of cavitation region is a key parameter to estimate the metallurgical effect of ultrasonic melt treatment (UST) on preferential structure refinement. We present a simple numerical model to predict the characteristic length of the cavitation region, termed cavitation depth, in a metal melt. The model is based on wave propagation with acoustic attenuation caused by cavitation bubbles which are dependent on bubble characteristics and ultrasonic intensity. In situ synchrotron X-ray imaging of cavitation bubbles has been made to quantitatively measure the size of cavitation region and volume fraction and size distribution of cavitation bubbles in an Al-Cu melt. The results show that cavitation bubbles maintain a log-normal size distribution, and the volume fraction of cavitation bubbles obeys a tanh function with the applied ultrasonic intensity. Using the experimental values of bubble characteristics as input, the predicted cavitation depth agrees well with observations except for a slight deviation at higher acoustic intensities. Further analysis shows that the increase of bubble volume and bubble size both leads to higher attenuation by cavitation bubbles, and hence, smaller cavitation depth. The current model offers a guideline to implement UST, especially for structural refinement.

  13. Liquefaction process for solid carbonaceous materials containing alkaline earth metal humates

    DOEpatents

    Epperly, William R.; Deane, Barry C.; Brunson, Roy J.

    1982-01-01

    An improved liquefaction process wherein wall scale and particulate agglomeration during the liquefaction of solid carbonaceous materials containing alkaline earth metal humates is reduced and/or eliminated by subjecting the solid carbonaceous materials to controlled cyclic cavitation during liquefaction. It is important that the solid carbonaceous material be slurried in a suitable solvent or diluent during liquefaction. The cyclic cavitation may be imparted via pressure cycling, cyclic agitation and the like. When pressure cycling or the like is employed an amplitude equivalent to at least 25 psia is required to effectively remove scale from the liquefaction vessel walls.

  14. CAVITATION DAMAGE STUDY VIA A NOVEL REPETITIVE PRESSURE PULSE APPROACH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Jy-An John; Ren, Fei; Wang, Hong

    2010-01-01

    Cavitation damage can significantly affect system performance. Thus, there is great interest in characterizing cavitation damage and improving materials resistance to cavitation damage. In this paper, we present a novel methodology to simulate cavitation environment. A pulsed laser is utilized to induce optical breakdown in the cavitation media, with the emission of shock wave and the generation of bubbles. The pressure waves induced by the optical breakdown fluctuate/propagate within the media, which enables the cavitation to occur and to further develop cavitation damage at the solid boundary. Using the repetitive pulsed-pressure apparatus developed in the current study, cavitation damage inmore » water media was verified on stainless steel and aluminum samples. Characteristic cavitation damages such as pitting and indentation are observed on sample surfaces using scanning electron microscopy.« less

  15. Stability of cavitation structures in a thin liquid layer.

    PubMed

    Wu, Pengfei; Bai, Lixin; Lin, Weijun; Yan, Jiuchun

    2017-09-01

    The inception and evolution of acoustic cavitation structures in thin liquid layers under different conditions and perturbations are investigated experimentally with high speed photography. The stability and characterization of cavitation structures are quantified by image analysis methods. It is found that cavitation structures (shape of bubble cloud and number of bubbles) are stable under unaltered experimental conditions, and the cavitation bubble cloud will return to the original structure and remain stable even in the face of large perturbations. When the experimental conditions are altered (for example, acoustic intensity, cavitation nuclei, boundary), the cavitation structures will vary correspondingly. Further analysis implies that the stability of cavitation structures is closely related to the number of bubbles in the cavitation bubble cloud. There are two mechanisms acting simultaneously in the cavitation bubble cloud evolution, one "bubble production" and the other "bubble disappearance". We propose that the two mechanisms acting together constitute the most likely explanation for the stability of cavitation structures and their transformation. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Synchrotron x-ray imaging of acoustic cavitation bubbles induced by acoustic excitation

    NASA Astrophysics Data System (ADS)

    Jung, Sung Yong; Park, Han Wook; Park, Sung Ho; Lee, Sang Joon

    2017-04-01

    The cavitation induced by acoustic excitation has been widely applied in various biomedical applications because cavitation bubbles can enhance the exchanges of mass and energy. In order to minimize the hazardous effects of the induced cavitation, it is essential to understand the spatial distribution of cavitation bubbles. The spatial distribution of cavitation bubbles visualized by the synchrotron x-ray imaging technique is compared to that obtained with a conventional x-ray tube. Cavitation bubbles with high density in the region close to the tip of the probe are visualized using the synchrotron x-ray imaging technique, however, the spatial distribution of cavitation bubbles in the whole ultrasound field is not detected. In this study, the effects of the ultrasound power of acoustic excitation and working medium on the shape and density of the induced cavitation bubbles are examined. As a result, the synchrotron x-ray imaging technique is useful for visualizing spatial distributions of cavitation bubbles, and it could be used for optimizing the operation conditions of acoustic cavitation.

  17. Processing of Microalgae: Acoustic Cavitation and Hydrothermal Conversion

    NASA Astrophysics Data System (ADS)

    Greenly, Justin Michael

    The production of energy dense fuels from renewable algal biomass feedstocks -- if sustainably developed at a sufficiently large scale -- may reduce the consumption of petroleum from fossil fuels and provide many environmental benefits. Achieving economic feasibility has several technical engineering challenges that arise from dilute concentration of growing algae in aqueous media, small cell sizes, and durable cell walls. For microalgae to be a sustainable source of biofuels and co-products, efficient fractionation and conversion of the cellular contents is necessary. Research was carried out to address two processing options for efficient microalgae biofuel production: 1. Ultrasonic cavitation for cell disruption and 2. Hydrothermal conversion of a model algal triglyceride. 1. Ultrasonic cell disruption, which relies on cavitating bubbles in the suspension to produce damaging shock waves, was investigated experimentally over a range of concentrations and species types. A few seconds of high intensity sonication at fixed frequency yielded significant cell disruption, even for the more durable cells. At longer exposure times, effectiveness was seen to decline and was attributed, using acoustic measurements, to ultrasonic power attenuation in the ensuing cloud of cavitating bubbles. Processing at higher cell concentrations slowed cell disintegration marginally, but increased the effectiveness of dissipating ultrasonic energy. A theoretical study effectively predicted optimal conditions for a variety of parameters that were inaccessible in this experimental investigation. In that study, single bubble collapse was modeled to identify operating conditions that would increase cavitation, and thus cell disruption. Simulations were conducted by varying frequency and pressure amplitude of the ultrasound wave, and initial bubble size. The simulation results indicated that low frequency, high sound wave amplitudes, and small initial bubble size generate the highest shock wave pressures. 2. Hydrolysis of a pure model triglyceride compound was experimentally examined for the first time at hydrothermal conditions -- from 225 to 300°C. Lipid product composition assessed by GC-FID was compared to previous studies with mixed vegetable oils and used to develop a kinetic model for this oil phase reaction.

  18. Empirical relations for cavitation and liquid impingement erosion processes

    NASA Technical Reports Server (NTRS)

    Rao, P. V.; Buckley, D. H.

    1984-01-01

    A unified power-law relationship between average erosion rate and cumulative erosion is presented. Extensive data analyses from venturi, magnetostriction (stationary and oscillating specimens), liquid drop, and jet impact devices appear to conform to this relation. A normalization technique using cavitation and liquid impingement erosion data is also presented to facilitate prediction. Attempts are made to understand the relationship between the coefficients in the power-law relationships and the material properties.

  19. Evaluation of the Destruction of the Harmful Cyanobacteria, Microcystis aeruginosa, with a Cavitation and Superoxide Generating Water Treatment Reactor.

    PubMed

    Medina, Victor F; Griggs, Chris S; Thomas, Catherine

    2016-06-01

    Cyanobacterial/Harmful Algal Blooms are a major issue for lakes and reservoirs throughout the U.S.A. An effective destructive technology could be useful to protect sensitive areas, such as areas near water intakes. The study presented in this article explored the use of a reactor called the KRIA Water Treatment System. The reactor focuses on the injection of superoxide (O2 (-)), which is generated electrochemically from the atmosphere, into the water body. In addition, the injection process generates a significant amount of cavitation. The treatment process was tested in 190-L reactors spiked with water from cyanobacterial contaminated lakes. The treatment was very effective at destroying the predominant species of cyanobacteria, Microcystis aeruginosa, organic matter, and decreasing chlorophyll concentration. Microcystin toxin concentrations were also reduced. Data suggest that cavitation alone was an effective treatment, but the addition of superoxide improved performance, particularly regarding removal of cyanobacteria and reduction of microcystin concentration.

  20. Bubbles in an acoustic field: an overview.

    PubMed

    Ashokkumar, Muthupandian; Lee, Judy; Kentish, Sandra; Grieser, Franz

    2007-04-01

    Acoustic cavitation is the fundamental process responsible for the initiation of most of the sonochemical reactions in liquids. Acoustic cavitation originates from the interaction between sound waves and bubbles. In an acoustic field, bubbles can undergo growth by rectified diffusion, bubble-bubble coalescence, bubble dissolution or bubble collapse leading to the generation of primary radicals and other secondary chemical reactions. Surface active solutes have been used in association with a number of experimental techniques in order to isolate and understand these activities. A strobe technique has been used for monitoring the growth of a single bubble by rectified diffusion. Multibubble sonoluminescence has been used for monitoring the growth of the bubbles as well as coalescence between bubbles. The extent of bubble coalescence has also been monitored using a newly developed capillary technique. An overview of the various experimental results has been presented in order to highlight the complexities involved in acoustic cavitation processes, which on the other hand arise from a simple, mechanical interaction between sound waves and bubbles.

  1. Degradation of 4-chloro 2-aminophenol using a novel combined process based on hydrodynamic cavitation, UV photolysis and ozone.

    PubMed

    Barik, Arati J; Gogate, Parag R

    2016-05-01

    The degradation of 4-chloro 2-aminophenol (4C2AP), an acute toxic organic compound, has been studied using different approaches based on the hydrodynamic cavitation (HC) with orifice plate as cavitating device, photolysis (UV) and ozonation (O3). The dependency of extent of degradation on operating parameters like operating pressure (2-5 bar), initial pH (3-8) and temperature (30-38 °C) have been established initially to maximize the efficacy of hydrodynamic cavitation. Subsequently the degradation has been studied using combined treatment strategies as HC+UV, HC+O3, UV+O3 and HC+UV+O3 at the established optimum parameters of operating temperature as 30 °C, initial pH of 6 and inlet pressure of 4 bar. The maximum extent of degradation as 96.85% and 73.6% reduction in TOC has been obtained using hydrodynamic cavitation in combination with UV photolysis and ozonation under the optimized operating conditions. The degradation products of 4C2AP have been identified using GC-MS. The present work has clearly established the efficacy of combined treatment approach (HC+UV+O3) for the removal of organic pollutant for the first time. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Pre-breakdown processes in a dielectric fluid in inhomogeneous pulsed electric fields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shneider, Mikhail N., E-mail: m.n.shneider@gmail.com; Pekker, Mikhail

    2015-06-14

    We consider the development of pre-breakdown cavitation nanopores appearing in the dielectric fluid under the influence of the electrostrictive stresses in the inhomogeneous pulsed electric field. It is shown that three characteristic regions can be distinguished near the needle electrode. In the first region, where the electric field gradient is greatest, the cavitation nanopores, occurring during the voltage nanosecond pulse, may grow to the size at which an electron accelerated by the field inside the pores can acquire enough energy for excitation and ionization of the liquid on the opposite pore wall, i.e., the breakdown conditions are satisfied. In themore » second region, the negative pressure caused by the electrostriction is large enough for the cavitation initiation (which can be registered by optical methods), but, during the voltage pulse, the pores do not reach the size at which the potential difference across their borders becomes sufficient for ionization or excitation of water molecules. And, in the third, the development of cavitation is impossible, due to an insufficient level of the negative pressure: in this area, the spontaneously occurring micropores do not grow and collapse under the influence of surface tension forces. This paper discusses the expansion dynamics of the cavitation pores and their most probable shape.« less

  3. The effect of ultrasound on enzymatic degumming process of rapeseed oil by the use of phospholipase A(1).

    PubMed

    Jiang, Xiaofei; Chang, Ming; Wang, Xiaosan; Jin, Qingzhe; Wang, Xingguo

    2014-01-01

    Comparative studies of enzymatic degumming process of rapeseed oil were carried out in mechanical-stirring and ultrasonic-assisted mechanical-stirring systems. The influences of enzyme dosage (10-50 mg/kg), pH (4.5-6), temperature (45-65 °C), water amount (1-3%), ultrasonic power (0.06-0.09 W/cm(3)) and reaction time were investigated subsequently. A suitable ultrasonic power of 0.07 W/cm(3) was determined to guarantee satisfactory degumming efficiency and enzyme activity. Compared to the mechanical-stirring system, optimum temperature of phospholipase A (PLA) in the ultrasonic-assisted mechanical-stirring system was about 5 °C higher, while the effects of pH on both of the two systems were quite similar. Less time and water were used in the ultrasonic-assisted mechanical-stirring system for enzymatic degumming. The study on the quality changes of degummed oils showed that ultrasound could accelerate the oxidation of edible oils due to the effect of cavitation, thus more attention should be paid on the oxidative stability in the further application. Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.

  4. Application of analyzer based X-ray imaging technique for detection of ultrasound induced cavitation bubbles from a physical therapy unit.

    PubMed

    Izadifar, Zahra; Belev, George; Babyn, Paul; Chapman, Dean

    2015-10-19

    The observation of ultrasound generated cavitation bubbles deep in tissue is very difficult. The development of an imaging method capable of investigating cavitation bubbles in tissue would improve the efficiency and application of ultrasound in the clinic. Among the previous imaging modalities capable of detecting cavitation bubbles in vivo, the acoustic detection technique has the positive aspect of in vivo application. However the size of the initial cavitation bubble and the amplitude of the ultrasound that produced the cavitation bubbles, affect the timing and amplitude of the cavitation bubbles' emissions. The spatial distribution of cavitation bubbles, driven by 0.8835 MHz therapeutic ultrasound system at output power of 14 Watt, was studied in water using a synchrotron X-ray imaging technique, Analyzer Based Imaging (ABI). The cavitation bubble distribution was investigated by repeated application of the ultrasound and imaging the water tank. The spatial frequency of the cavitation bubble pattern was evaluated by Fourier analysis. Acoustic cavitation was imaged at four different locations through the acoustic beam in water at a fixed power level. The pattern of cavitation bubbles in water was detected by synchrotron X-ray ABI. The spatial distribution of cavitation bubbles driven by the therapeutic ultrasound system was observed using ABI X-ray imaging technique. It was observed that the cavitation bubbles appeared in a periodic pattern. The calculated distance between intervals revealed that the distance of frequent cavitation lines (intervals) is one-half of the acoustic wave length consistent with standing waves. This set of experiments demonstrates the utility of synchrotron ABI for visualizing cavitation bubbles formed in water by clinical ultrasound systems working at high frequency and output powers as low as a therapeutic system.

  5. Fluid dynamics of acoustic and hydrodynamic cavitation in hydraulic power systems.

    PubMed

    Ferrari, A

    2017-03-01

    Cavitation is the transition from a liquid to a vapour phase, due to a drop in pressure to the level of the vapour tension of the fluid. Two kinds of cavitation have been reviewed here: acoustic cavitation and hydrodynamic cavitation. As acoustic cavitation in engineering systems is related to the propagation of waves through a region subjected to liquid vaporization, the available expressions of the sound speed are discussed. One of the main effects of hydrodynamic cavitation in the nozzles and orifices of hydraulic power systems is a reduction in flow permeability. Different discharge coefficient formulae are analysed in this paper: the Reynolds number and the cavitation number result to be the key fluid dynamical parameters for liquid and cavitating flows, respectively. The latest advances in the characterization of different cavitation regimes in a nozzle, as the cavitation number reduces, are presented. The physical cause of choked flows is explained, and an analogy between cavitation and supersonic aerodynamic flows is proposed. The main approaches to cavitation modelling in hydraulic power systems are also reviewed: these are divided into homogeneous-mixture and two-phase models. The homogeneous-mixture models are further subdivided into barotropic and baroclinic models. The advantages and disadvantages of an implementation of the complete Rayleigh-Plesset equation are examined.

  6. Fluid dynamics of acoustic and hydrodynamic cavitation in hydraulic power systems

    NASA Astrophysics Data System (ADS)

    Ferrari, A.

    2017-03-01

    Cavitation is the transition from a liquid to a vapour phase, due to a drop in pressure to the level of the vapour tension of the fluid. Two kinds of cavitation have been reviewed here: acoustic cavitation and hydrodynamic cavitation. As acoustic cavitation in engineering systems is related to the propagation of waves through a region subjected to liquid vaporization, the available expressions of the sound speed are discussed. One of the main effects of hydrodynamic cavitation in the nozzles and orifices of hydraulic power systems is a reduction in flow permeability. Different discharge coefficient formulae are analysed in this paper: the Reynolds number and the cavitation number result to be the key fluid dynamical parameters for liquid and cavitating flows, respectively. The latest advances in the characterization of different cavitation regimes in a nozzle, as the cavitation number reduces, are presented. The physical cause of choked flows is explained, and an analogy between cavitation and supersonic aerodynamic flows is proposed. The main approaches to cavitation modelling in hydraulic power systems are also reviewed: these are divided into homogeneous-mixture and two-phase models. The homogeneous-mixture models are further subdivided into barotropic and baroclinic models. The advantages and disadvantages of an implementation of the complete Rayleigh-Plesset equation are examined.

  7. Fluid dynamics of acoustic and hydrodynamic cavitation in hydraulic power systems

    PubMed Central

    2017-01-01

    Cavitation is the transition from a liquid to a vapour phase, due to a drop in pressure to the level of the vapour tension of the fluid. Two kinds of cavitation have been reviewed here: acoustic cavitation and hydrodynamic cavitation. As acoustic cavitation in engineering systems is related to the propagation of waves through a region subjected to liquid vaporization, the available expressions of the sound speed are discussed. One of the main effects of hydrodynamic cavitation in the nozzles and orifices of hydraulic power systems is a reduction in flow permeability. Different discharge coefficient formulae are analysed in this paper: the Reynolds number and the cavitation number result to be the key fluid dynamical parameters for liquid and cavitating flows, respectively. The latest advances in the characterization of different cavitation regimes in a nozzle, as the cavitation number reduces, are presented. The physical cause of choked flows is explained, and an analogy between cavitation and supersonic aerodynamic flows is proposed. The main approaches to cavitation modelling in hydraulic power systems are also reviewed: these are divided into homogeneous-mixture and two-phase models. The homogeneous-mixture models are further subdivided into barotropic and baroclinic models. The advantages and disadvantages of an implementation of the complete Rayleigh–Plesset equation are examined. PMID:28413332

  8. Cavitating behaviour analysis of Darrieus-type cross flow water turbines

    NASA Astrophysics Data System (ADS)

    Aumelas, V.; Pellone, C.; Maître, T.

    2010-08-01

    The aim of this paper is to study the cavitating behaviour of bare Darrieus-type turbines. For that, the RANS code CAVKA, has been used. Under non-cavitating conditions, the power coefficient and the thrusts calculated with CAVKA are compared to experimental values obtained in the LEGI hydrodynamic tunnel. Under cavitating conditions, for several cavitation numbers, the numerical power coefficients and vapour structures are compared to experimental ones. Different blade profiles and camber lines are also studied for non-cavitating and cavitating conditions.

  9. A New Unsteady Model for Dense Cloud Cavitation in Cryogenic Fluids

    NASA Technical Reports Server (NTRS)

    Hosangadi, Ashvin; Ahuja, Vineet

    2005-01-01

    Contents include the following: Background on thermal effects in cavitation. Physical properties of hydrogen. Multi-phase cavitation with thermal effect. Solution procedure. Cavitation model overview. Cavitation source terms. New cavitation model. Source term for bubble growth. One equation les model. Unsteady ogive simulations: liquid nitrogen. Unsteady incompressible flow in a pipe. Time averaged cavity length for NACA15 flowfield.

  10. Study on Effects of The Shape of Cavitator on Supercavitation Flow Field Characteristics

    NASA Astrophysics Data System (ADS)

    Wang, Rui; Dang, Jianjun; Yao, Zhong

    2018-03-01

    The cavitator is the key part of the nose of the vehicle to induce the formation of supercavity, which has an important influence in the cavity formation rate, cavity shape and cavity stability. To study the influence of the shape on the supercavitation flew field characteristics, the cavity characteristics and the resistance characteristics of different shapes of cavitator under different working conditions are obtained by combining technical methods of numerical simulation and experimental research in water tunnel. The simulation results are contrast and analyzed with the test results. The analysis results show that : in terms of the cavity size, the inverted-conic cavitator can form the biggest cavity size, followed by the disk cavitator, and the truncated-conic cavitator is the least; in terms of the cavity formation speed, the inverted-conic cavitator has the fastest cavity formation speed, then is the truncated-conic cavitator, and the disk cavitator is the least; in terms of the drag characteristic, the truncated-conic cavitator has the maximum coefficient, disk cavitator is the next, the inverted-conic cavitator is the minimal. The research conclusion can provide reference and basis for the head shape design of supercavitating underwater ordnance and the design of hydrodynamic layout.

  11. Super-Cavitating Flow Around Two-Dimensional Conical, Spherical, Disc and Stepped Disc Cavitators

    NASA Astrophysics Data System (ADS)

    Sooraj, S.; Chandrasekharan, Vaishakh; Robson, Rony S.; Bhanu Prakash, S.

    2017-08-01

    A super-cavitating object is a high speed submerged object that is designed to initiate a cavitation bubble at the nose which extends past the aft end of the object, substantially reducing the skin friction drag that would be present if the sides of the object were in contact with the liquid in which the object is submerged. By reducing the drag force the thermal energy consumption to move faster can also be minimised. The super-cavitation behavioural changes with respect to Cavitators of various geometries have been studied by varying the inlet velocity. Two-dimensional computational fluid dynamics analysis has been carried out by applying k-ε turbulence model. The variation of drag coefficient, cavity length with respect to cavitation number and inlet velocity are analyzed. Results showed conical Cavitator with wedge angle of 30° has lesser drag coefficient and cavity length when compared to conical Cavitators with wedge angles 45° and 60°, spherical, disc and stepped disc Cavitators. Conical cavitator 60° and disc cavitator have the maximum cavity length but with higher drag coefficient. Also there is significant variation of supercavitation effect observed between inlet velocities of 32 m/s to 40 m/s.

  12. Review on Lithotripsy and Cavitation in Urinary Stone Therapy.

    PubMed

    Ghorbani, Morteza; Oral, Ozlem; Ekici, Sinan; Gozuacik, Devrim; Kosar, Ali

    2016-01-01

    Cavitation is the sudden formation of vapor bubbles or voids in liquid media and occurs after rapid changes in pressure as a consequence of mechanical forces. It is mostly an undesirable phenomenon. Although the elimination of cavitation is a major topic in the study of fluid dynamics, its destructive nature could be exploited for therapeutic applications. Ultrasonic and hydrodynamic sources are two main origins for generating cavitation. The purpose of this review is to give the reader a general idea about the formation of cavitation phenomenon and existing biomedical applications of ultrasonic and hydrodynamic cavitation. Because of the high number of the studies on ultrasound cavitation in the literature, the main focus of this review is placed on the lithotripsy techniques, which have been widely used for the treatment of urinary stones. Accordingly, cavitation phenomenon and its basic concepts are presented in Section II. The significance of the ultrasound cavitation in the urinary stone treatment is discussed in Section III in detail and hydrodynamic cavitation as an important alternative for the ultrasound cavitation is included in Section IV. Finally, side effects of using both ultrasound and hydrodynamic cavitation in biomedical applications are presented in Section V.

  13. Microbubble Cavitation Imaging

    PubMed Central

    Vignon, Francois; Shi, William T.; Powers, Jeffry E.; Everbach, E. Carr; Liu, Jinjin; Gao, Shunji; Xie, Feng; Porter, Thomas R.

    2014-01-01

    Ultrasound cavitation of microbubble contrast agents has a potential for therapeutic applications such as sonothrombolysis (STL) in acute ischemic stroke. For safety, efficacy, and reproducibility of treatment, it is critical to evaluate the cavitation state (moderate oscillations, stable cavitation, and inertial cavitation) and activity level in and around a treatment area. Acoustic passive cavitation detectors (PCDs) have been used to this end but do not provide spatial information. This paper presents a prototype of a 2-D cavitation imager capable of producing images of the dominant cavitation state and activity level in a region of interest. Similar to PCDs, the cavitation imaging described here is based on the spectral analysis of the acoustic signal radiated by the cavitating microbubbles: ultraharmonics of the excitation frequency indicate stable cavitation, whereas elevated noise bands indicate inertial cavitation; the absence of both indicates moderate oscillations. The prototype system is a modified commercially available ultrasound scanner with a sector imaging probe. The lateral resolution of the system is 1.5 mm at a focal depth of 3 cm, and the axial resolution is 3 cm for a therapy pulse length of 20 µs. The maximum frame rate of the prototype is 2 Hz. The system has been used for assessing and mapping the relative importance of the different cavitation states of a microbubble contrast agent. In vitro (tissue-mimicking flow phantom) and in vivo (heart, liver, and brain of two swine) results for cavitation states and their changes as a function of acoustic amplitude are presented. PMID:23549527

  14. Cavitation in flowing superfluid helium

    NASA Technical Reports Server (NTRS)

    Daney, D. E.

    1988-01-01

    Flowing superfluid helium cavitates much more readily than normal liquid helium, and there is a marked difference in the cavitation behavior of the two fluids as the lambda point is traversed. Examples of cavitation in a turbine meter and centrifugal pump are given, together with measurements of the cavitation strength of flowing superfluid helium. The unusual cavitation behavior of superfluid helium is attributed to its immense thermal conductivity .

  15. Simultaneous pressure measurement and high-speed photography study of cavitation in a dynamically loaded journal bearing

    NASA Technical Reports Server (NTRS)

    Sun, D. C.; Brewe, D. E.; Abel, P. B.

    1993-01-01

    Cavitation of the oil film in a dynamically loaded journal bearing was studied using high-speed photography and pressure measurement simultaneously. Comparison of the visual and pressure data provided considerable insight into the occurence and non-occurrence of cavitation. It was found that (1), cavitation typically occurred in the form of one bubble with the pressure in the cavitation bubble close to the absolute zero; and (2), for cavitation-producing operating conditions, cavitation did not always occur; with the oil film then supporting a tensile stress.

  16. Relationship between loss of echogenicity and cavitation emissions from echogenic liposomes insonified by spectral Doppler ultrasound

    NASA Astrophysics Data System (ADS)

    Radhakrishnan, Kirthi

    Cardiovascular disease is the leading cause of death and disability in the United States and worldwide. Echogenic liposomes (ELIP) are theragonistic ultrasound contrast agents (UCAs) being developed for the early detection and treatment of cardiovascular disease. Stability of the echogenicity of ELIP in physiologic conditions is crucial to their successful translation to clinical use. The stability of ELIP echogenicity was determined in vitro under physiologic conditions of total dissolved gas concentration, temperature, and hydrodynamic pressure in porcine plasma and whole blood. Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation as a function of pulse duration and pulse repetition frequency (PRF). Previous studies have also demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of ELIP as a function of pulse duration and pulse repetition frequency. Determining the relationship between cavitation thresholds and loss of echogenicity of ELIP would enable monitoring of cavitation based upon the on-screen echogenicity in clinical applications. ELIP were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations and four PRFs in a static fluid and in a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a single-element passive cavitation detection (PCD) system and a passive cavitation imaging (PCI) system. Stable and inertial cavitation thresholds were ascertained. Loss of echogenicity from ELIP was assessed within regions of interest on B-mode images. Stable cavitation thresholds were found to be lower than inertial cavitation thresholds. Stable and inertial cavitation thresholds of ELIP were found to have a weak dependence on pulse duration. However, the stable cavitation threshold of ELIP had no dependence on PRF. The inertial cavitation threshold of ELIP had a weak dependence on PRF. Cavitation thresholds ascertained using a PCI agreed with the thresholds ascertained using a single-element PCD. The azimuthal beamwidth of the cavitation emissions detected by the PCI system agreed with the calibrated beamwidth of the insonation Doppler pressure exceeding the cavitation threshold. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. ELIP lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation emissions were detected in the physiologic flow phantom. These results indicate that 80% loss of echogenicity may be used as a qualitative metric to gauge the onset of stable and inertial cavitation from ELIP.

  17. Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal.

    PubMed

    Schwendicke, F; Frencken, J E; Bjørndal, L; Maltz, M; Manton, D J; Ricketts, D; Van Landuyt, K; Banerjee, A; Campus, G; Doméjean, S; Fontana, M; Leal, S; Lo, E; Machiulskiene, V; Schulte, A; Splieth, C; Zandona, A F; Innes, N P T

    2016-05-01

    The International Caries Consensus Collaboration undertook a consensus process and here presents clinical recommendations for carious tissue removal and managing cavitated carious lesions, including restoration, based on texture of demineralized dentine. Dentists should manage the disease dental caries and control activity of existing cavitated lesions to preserve hard tissues and retain teeth long-term. Entering the restorative cycle should be avoided as far as possible. Controlling the disease in cavitated carious lesions should be attempted using methods which are aimed at biofilm removal or control first. Only when cavitated carious lesions either are noncleansable or can no longer be sealed are restorative interventions indicated. When a restoration is indicated, the priorities are as follows: preserving healthy and remineralizable tissue, achieving a restorative seal, maintaining pulpal health, and maximizing restoration success. Carious tissue is removed purely to create conditions for long-lasting restorations. Bacterially contaminated or demineralized tissues close to the pulp do not need to be removed. In deeper lesions in teeth with sensible (vital) pulps, preserving pulpal health should be prioritized, while in shallow or moderately deep lesions, restoration longevity becomes more important. For teeth with shallow or moderately deep cavitated lesions, carious tissue removal is performed according toselective removal to firm dentine.In deep cavitated lesions in primary or permanent teeth,selective removal to soft dentineshould be performed, although in permanent teeth,stepwise removalis an option. The evidence and, therefore, these recommendations support less invasive carious lesion management, delaying entry to, and slowing down, the restorative cycle by preserving tooth tissue and retaining teeth long-term. © International & American Associations for Dental Research 2016.

  18. Studies on the Tempo of Bubble Formation in Recently Cavitated Vessels: A Model to Predict the Pressure of Air Bubbles1

    PubMed Central

    Wang, Yujie; Pan, Ruihua; Tyree, Melvin T.

    2015-01-01

    A cavitation event in a vessel replaces water with a mixture of water vapor and air. A quantitative theory is presented to argue that the tempo of filling of vessels with air has two phases: a fast process that extracts air from stem tissue adjacent to the cavitated vessels (less than 10 s) and a slow phase that extracts air from the atmosphere outside the stem (more than 10 h). A model was designed to estimate how water tension (T) near recently cavitated vessels causes bubbles in embolized vessels to expand or contract as T increases or decreases, respectively. The model also predicts that the hydraulic conductivity of a stem will increase as bubbles collapse. The pressure of air bubbles trapped in vessels of a stem can be predicted from the model based on fitting curves of hydraulic conductivity versus T. The model was validated using data from six stem segments each of Acer mono and the clonal hybrid Populus 84K (Populus alba × Populus glandulosa). The model was fitted to results with root mean square error less than 3%. The model provided new insight into the study of embolism formation in stem tissue and helped quantify the bubble pressure immediately after the fast process referred to above. PMID:25907963

  19. Studies on the tempo of bubble formation in recently cavitated vessels: a model to predict the pressure of air bubbles.

    PubMed

    Wang, Yujie; Pan, Ruihua; Tyree, Melvin T

    2015-06-01

    A cavitation event in a vessel replaces water with a mixture of water vapor and air. A quantitative theory is presented to argue that the tempo of filling of vessels with air has two phases: a fast process that extracts air from stem tissue adjacent to the cavitated vessels (less than 10 s) and a slow phase that extracts air from the atmosphere outside the stem (more than 10 h). A model was designed to estimate how water tension (T) near recently cavitated vessels causes bubbles in embolized vessels to expand or contract as T increases or decreases, respectively. The model also predicts that the hydraulic conductivity of a stem will increase as bubbles collapse. The pressure of air bubbles trapped in vessels of a stem can be predicted from the model based on fitting curves of hydraulic conductivity versus T. The model was validated using data from six stem segments each of Acer mono and the clonal hybrid Populus 84 K (Populus alba × Populus glandulosa). The model was fitted to results with root mean square error less than 3%. The model provided new insight into the study of embolism formation in stem tissue and helped quantify the bubble pressure immediately after the fast process referred to above. © 2015 American Society of Plant Biologists. All Rights Reserved.

  20. Measurements of void fraction distribution in cavitating pipe flow using x-ray CT

    NASA Astrophysics Data System (ADS)

    Bauer, D.; Chaves, H.; Arcoumanis, C.

    2012-05-01

    Measuring the void fraction distribution is still one of the greatest challenges in cavitation research. In this paper, a measurement technique for the quantitative void fraction characterization in a cavitating pipe flow is presented. While it is almost impossible to visualize the inside of the cavitation region with visible light, it is shown that with x-ray computed tomography (CT) it is possible to capture the time-averaged void fraction distribution in a quasi-steady pipe flow. Different types of cavitation have been investigated including cloud-like cavitation, bubble cavitation and film cavitation at very high flow rates. A specially designed nozzle was employed to induce very stable quasi-steady cavitation. The obtained results demonstrate the advantages of the measurement technique compared to other ones; for example, structures were observed inside the cavitation region that could not be visualized by photographic images. Furthermore, photographic images and pressure measurements were used to allow comparisons to be made and to prove the superiority of the CT measurement technique.

  1. Numerical investigations on cavitation intensity for 3D homogeneous unsteady viscous flows

    NASA Astrophysics Data System (ADS)

    Leclercq, C.; Archer, A.; Fortes-Patella, R.

    2016-11-01

    The cavitation erosion remains an industrial issue. In this paper, we deal with the cavitation intensity which can be described as the aggressiveness - or erosive capacity - of a cavitating flow. The estimation of this intensity is a challenging problem both in terms of modelling the cavitating flow and predicting the erosion due to cavitation. For this purpose, a model was proposed to estimate cavitation intensity from 3D unsteady cavitating flow simulations. An intensity model based on pressure and void fraction derivatives was developped and applied to a NACA 65012 hydrofoil tested at LMH-EPFL (École Polytechnique Fédérale de Lausanne) [1]. 2D and 3D unsteady cavitating simulations were performed using a homogeneous model with void fraction transport equation included in Code_Saturne with cavitating module [2]. The article presents a description of the numerical code and the physical approach considered. Comparisons between 2D and 3D simulations, as well as between numerical and experimental results obtained by pitting tests, are analyzed in the paper.

  2. Characterization of string cavitation in large-scale Diesel nozzles with tapered holes

    NASA Astrophysics Data System (ADS)

    Gavaises, M.; Andriotis, A.; Papoulias, D.; Mitroglou, N.; Theodorakakos, A.

    2009-05-01

    The cavitation structures formed inside enlarged transparent replicas of tapered Diesel valve covered orifice nozzles have been characterized using high speed imaging visualization. Cavitation images obtained at fixed needle lift and flow rate conditions have revealed that although the conical shape of the converging tapered holes suppresses the formation of geometric cavitation, forming at the entry to the cylindrical injection hole, string cavitation has been found to prevail, particularly at low needle lifts. Computational fluid dynamics simulations have shown that cavitation strings appear in areas where large-scale vortices develop. The vortical structures are mainly formed upstream of the injection holes due to the nonuniform flow distribution and persist also inside them. Cavitation strings have been frequently observed to link adjacent holes while inspection of identical real-size injectors has revealed cavitation erosion sites in the area of string cavitation development. Image postprocessing has allowed estimation of their frequency of appearance, lifetime, and size along the injection hole length, as function of cavitation and Reynolds numbers and needle lift.

  3. Acoustic methods for cavitation mapping in biomedical applications

    NASA Astrophysics Data System (ADS)

    Wan, M.; Xu, S.; Ding, T.; Hu, H.; Liu, R.; Bai, C.; Lu, S.

    2015-12-01

    In recent years, cavitation is increasingly utilized in a wide range of applications in biomedical field. Monitoring the spatial-temporal evolution of cavitation bubbles is of great significance for efficiency and safety in biomedical applications. In this paper, several acoustic methods for cavitation mapping proposed or modified on the basis of existing work will be presented. The proposed novel ultrasound line-by-line/plane-by-plane method can depict cavitation bubbles distribution with high spatial and temporal resolution and may be developed as a potential standard 2D/3D cavitation field mapping method. The modified ultrafast active cavitation mapping based upon plane wave transmission and reception as well as bubble wavelet and pulse inversion technique can apparently enhance the cavitation to tissue ratio in tissue and further assist in monitoring the cavitation mediated therapy with good spatial and temporal resolution. The methods presented in this paper will be a foundation to promote the research and development of cavitation imaging in non-transparent medium.

  4. Alternative approach for cavitation damage study utilizing repetitive laser pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ren, Fei; Wang, Jy-An John; Wang, Hong

    2010-01-01

    Cavitation is a common phenomenon in fluid systems that can lead to dramatic degradation of solid materials surface in contact with the cavitating media. Study of cavitation damage has great significance in many engineering fields. Current techniques for cavitation damage study either require large scale equipments or tend to introduce damages from other mechanisms. In this project, we utilized the cavitation phenomenon induced by laser optical breakdown and developed a prototype apparatus for cavitation damage study. In our approach, cavitation was generated by the repetitive pressure waves induced by high-power laser pulses. As proof of principal study, stainless steel andmore » aluminum samples were tested using the novel apparatus. Surface characterization via scanning electron microscopy revealed damages such as indentation and surface pitting, which were similar to those reported in literature using other state-of-the-art techniques. These preliminary results demonstrated the new device was capable of generating cavitation damages and could be used as an alternative method for cavitation damage study.« less

  5. RANS computations for identification of 1-D cavitation model parameters: application to full load cavitation vortex rope

    NASA Astrophysics Data System (ADS)

    Alligné, S.; Decaix, J.; Müller, A.; Nicolet, C.; Avellan, F.; Münch, C.

    2017-04-01

    Due to the massive penetration of alternative renewable energies, hydropower is a key energy conversion technology for stabilizing the electrical power network by using hydraulic machines at off design operating conditions. At full load, the axisymmetric cavitation vortex rope developing in Francis turbines acts as an internal source of energy, leading to an instability commonly referred to as self-excited surge. 1-D models are developed to predict this phenomenon and to define the range of safe operating points for a hydropower plant. These models require a calibration of several parameters. The present work aims at identifying these parameters by using CFD results as objective functions for an optimization process. A 2-D Venturi and 3-D Francis turbine are considered.

  6. Hydrodynamic cavitation kills prostate cells and ablates benign prostatic hyperplasia tissue.

    PubMed

    Itah, Zeynep; Oral, Ozlem; Perk, Osman Yavuz; Sesen, Muhsincan; Demir, Ebru; Erbil, Secil; Dogan-Ekici, A Isin; Ekici, Sinan; Kosar, Ali; Gozuacik, Devrim

    2013-11-01

    Hydrodynamic cavitation is a physical phenomenon characterized by vaporization and bubble formation in liquids under low local pressures, and their implosion following their release to a higher pressure environment. Collapse of the bubbles releases high energy and may cause damage to exposed surfaces. We recently designed a set-up to exploit the destructive nature of hydrodynamic cavitation for biomedical purposes. We have previously shown that hydrodynamic cavitation could kill leukemia cells and erode kidney stones. In this study, we analyzed the effects of cavitation on prostate cells and benign prostatic hyperplasia (BPH) tissue. We showed that hydrodynamic cavitation could kill prostate cells in a pressure- and time-dependent manner. Cavitation did not lead to programmed cell death, i.e. classical apoptosis or autophagy activation. Following the application of cavitation, we observed no prominent DNA damage and cells did not arrest in the cell cycle. Hence, we concluded that cavitation forces directly damaged the cells, leading to their pulverization. Upon application to BPH tissues from patients, cavitation could lead to a significant level of tissue destruction. Therefore similar to ultrasonic cavitation, we propose that hydrodynamic cavitation has the potential to be exploited and developed as an approach for the ablation of aberrant pathological tissues, including BPH.

  7. Assessment of cavitation in artificial approximal dental lesions with near-IR imaging

    NASA Astrophysics Data System (ADS)

    Simon, Jacob C.; Darling, Cynthia L.; Fried, Daniel

    2017-02-01

    Bitewing radiography is still considered state-of-the-art diagnostic technology for assessing cavitation within approximal carious dental lesions, even though radiographs cannot resolve cavitated surfaces but instead are used to measure lesion depth in order to predict cavitation. Clinicians need new technologies capable of determining whether approximal carious lesions have become cavitated because not all lesions progress to cavitation. Assessing lesion cavitation from near-infrared (NIR) imaging methods holds great potential due to the high transparency of enamel in the NIR region from λ=1300-1700-nm, which allows direct visualization and quantified measurements of enamel demineralization. The objective of this study was to measure the change in lesion appearance between non-cavitated and cavitated lesions in artificially generated lesions using NIR imaging modalities (two-dimensional) at λ=1300-nm and λ=1450-nm and cross-polarization optical coherence tomography (CP-OCT) (thee-dimensional) λ=1300-nm. Extracted human posterior teeth with sound proximal surfaces were chosen for this study and imaged before and after artificial lesions were made. A high speed dental hand piece was used to create artificial cavitated proximal lesions in sound samples and imaged. The cavitated artificial lesions were then filled with hydroxyapatite powder to simulate non-cavitated proximal lesions.

  8. Assessment of cavitation in artificial approximal dental lesions with near-IR imaging.

    PubMed

    Simon, Jacob C; Darling, Cynthia L; Fried, Daniel

    2017-01-28

    Bitewing radiography is still considered state-of-the-art diagnostic technology for assessing cavitation within approximal carious dental lesions, even though radiographs cannot resolve cavitated surfaces but instead are used to measure lesion depth in order to predict cavitation. Clinicians need new technologies capable of determining whether approximal carious lesions have become cavitated because not all lesions progress to cavitation. Assessing lesion cavitation from near-infrared (NIR) imaging methods holds great potential due to the high transparency of enamel in the NIR region from λ=1300-1700-nm, which allows direct visualization and quantified measurements of enamel demineralization. The objective of this study was to measure the change in lesion appearance between non-cavitated and cavitated lesions in artificially generated lesions using NIR imaging modalities (two-dimensional) at λ =1300-nm and λ=1450-nm and cross-polarization optical coherence tomography (CP-OCT) (thee-dimensional) λ =1300-nm. Extracted human posterior teeth with sound proximal surfaces were chosen for this study and imaged before and after artificial lesions were made. A high speed dental hand piece was used to create artificial cavitated proximal lesions in sound samples and imaged. The cavitated artificial lesions were then filled with hydroxyapatite powder to simulate non-cavitated proximal lesions.

  9. Seasonality of cavitation and frost fatigue in Acer mono Maxim.

    PubMed

    Zhang, Wen; Feng, Feng; Tyree, Melvin T

    2017-12-08

    Although cavitation is common in plants, it is unknown whether the cavitation resistance of xylem is seasonally constant or variable. We tested the changes in cavitation resistance of Acer mono before and after a controlled cavitation-refilling and freeze-thaw cycles for a whole year. Cavitation resistance was determined from 'vulnerability curves' showing the percent loss of conductivity versus xylem tension. Cavitation fatigue was defined as a reduction of cavitation resistance following a cavitation-refilling cycle, whereas frost fatigue was caused by a freeze-thaw cycle. A. mono developed seasonal changes in native embolisms; values were relatively high during winter but relatively low and constant throughout the growing season. Cavitation fatigue occurred and changed seasonally during the 12-month cycle; the greatest fatigue response occurred during summer and the weakest during winter, and the transitions occurred during spring and autumn. A. mono was highly resistant to frost damage during the relatively mild winter months; however, a quite different situation occurred during the growing season, as the seasonal trend of frost fatigue was strikingly similar to that of cavitation fatigue. Seasonality changes in cavitation resistance may be caused by seasonal changes in the mechanical properties of the pit membranes. © 2017 John Wiley & Sons Ltd.

  10. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents

    NASA Astrophysics Data System (ADS)

    Radhakrishnan, Kirthi; Bader, Kenneth B.; Haworth, Kevin J.; Kopechek, Jonathan A.; Raymond, Jason L.; Huang, Shao-Ling; McPherson, David D.; Holland, Christy K.

    2013-09-01

    Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pulse-duration-dependent pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation. Previous studies have demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of UCAs as a function of pulse duration. Determining the relationship between cavitation thresholds and loss of echogenicity of UCAs would enable monitoring of cavitation based upon the onscreen echogenicity in clinical applications. Two lipid-shelled UCAs, echogenic liposomes (ELIP) and Definity®, were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations (‘sample volumes’) in both a static system and a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a passive cavitation detection system and stable and inertial cavitation thresholds ascertained. Loss of echogenicity from ELIP and Definity® was assessed within regions of interest on B-mode images. A numerical model based on UCA rupture predicted the functional form of the loss of echogenicity from ELIP and Definity®. Stable and inertial cavitation thresholds were found to have a weak dependence on pulse duration. Stable cavitation thresholds were lower than inertial cavitation thresholds. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. Both ELIP and Definity® lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation were detected in the physiologic flow phantom. These results imply that stable and inertial cavitation are necessary in order to trigger complete loss of echogenicity acoustically from UCAs and this finding can be used when planning diagnostic and therapeutic applications.

  11. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents

    PubMed Central

    Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K

    2014-01-01

    Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pulse-duration dependent pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation. Previous studies have demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of UCAs as a function of pulse duration. Determining the relationship between cavitation thresholds and loss of echogenicity of UCAs would enable monitoring of cavitation based upon the on-screen echogenicity in clinical applications. Two lipid-shelled UCAs, echogenic liposomes (ELIP) and Definity®, were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations (“sample volumes”) in both a static system and a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a passive cavitation detection system and stable and inertial cavitation thresholds ascertained. Loss of echogenicity from ELIP and Definity® was assessed within regions of interest on B-mode images. A numerical model based on UCA rupture predicted the functional form of the loss of echogenicity from ELIP and Definity®. Stable and inertial cavitation thresholds were found to have a weak dependence on pulse duration. Stable cavitation thresholds were lower than inertial cavitation thresholds. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. Both ELIP and Definity® lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation were detected in the physiologic flow phantom. These results imply that stable and inertial cavitation are necessary in order to trigger complete loss of echogenicity acoustically from UCAs and this finding can be used when planning diagnostic and therapeutic applications. PMID:24002637

  12. Relationship between cavitation and loss of echogenicity from ultrasound contrast agents.

    PubMed

    Radhakrishnan, Kirthi; Bader, Kenneth B; Haworth, Kevin J; Kopechek, Jonathan A; Raymond, Jason L; Huang, Shao-Ling; McPherson, David D; Holland, Christy K

    2013-09-21

    Ultrasound contrast agents (UCAs) have the potential to nucleate cavitation and promote both beneficial and deleterious bioeffects in vivo. Previous studies have elucidated the pulse-duration-dependent pressure amplitude threshold for rapid loss of echogenicity due to UCA fragmentation. Previous studies have demonstrated that UCA fragmentation was concomitant with inertial cavitation. The purpose of this study was to evaluate the relationship between stable and inertial cavitation thresholds and loss of echogenicity of UCAs as a function of pulse duration. Determining the relationship between cavitation thresholds and loss of echogenicity of UCAs would enable monitoring of cavitation based upon the onscreen echogenicity in clinical applications. Two lipid-shelled UCAs, echogenic liposomes (ELIP) and Definity®, were insonified by a clinical ultrasound scanner in duplex spectral Doppler mode at four pulse durations ('sample volumes') in both a static system and a flow system. Cavitation emissions from the UCAs insonified by Doppler pulses were recorded using a passive cavitation detection system and stable and inertial cavitation thresholds ascertained. Loss of echogenicity from ELIP and Definity® was assessed within regions of interest on B-mode images. A numerical model based on UCA rupture predicted the functional form of the loss of echogenicity from ELIP and Definity®. Stable and inertial cavitation thresholds were found to have a weak dependence on pulse duration. Stable cavitation thresholds were lower than inertial cavitation thresholds. The power of cavitation emissions was an exponential function of the loss of echogenicity over the investigated range of acoustic pressures. Both ELIP and Definity® lost more than 80% echogenicity before the onset of stable or inertial cavitation. Once this level of echogenicity loss occurred, both stable and inertial cavitation were detected in the physiologic flow phantom. These results imply that stable and inertial cavitation are necessary in order to trigger complete loss of echogenicity acoustically from UCAs and this finding can be used when planning diagnostic and therapeutic applications.

  13. Three-dimensional reconstruction of rat knee joint using episcopic fluorescence image capture.

    PubMed

    Takaishi, R; Aoyama, T; Zhang, X; Higuchi, S; Yamada, S; Takakuwa, T

    2014-10-01

    Development of the knee joint was morphologically investigated, and the process of cavitation was analyzed by using episcopic fluorescence image capture (EFIC) to create spatial and temporal three-dimensional (3D) reconstructions. Knee joints of Wister rat embryos between embryonic day (E)14 and E20 were investigated. Samples were sectioned and visualized using an EFIC. Then, two-dimensional image stacks were reconstructed using OsiriX software, and 3D reconstructions were generated using Amira software. Cavitations of the knee joint were constructed from five divided portions. Cavity formation initiated at multiple sites at E17; among them, the femoropatellar cavity (FPC) was the first. Cavitations of the medial side preceded those of the lateral side. Each cavity connected at E20 when cavitations around the anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) were completed. Cavity formation initiated from six portions. In each portion, development proceeded asymmetrically. These results concerning anatomical development of the knee joint using EFIC contribute to a better understanding of the structural feature of the knee joint. Copyright © 2014 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

  14. Dynamic analysis on cavitation and embolization in vascular plants under tension

    NASA Astrophysics Data System (ADS)

    Ryu, Jeongeun; Hwang, Bae Geun; Kim, Yangmin; Lee, Sang Joon

    2014-11-01

    Plants can transport sap water from the soil to the tip of their leaves using the tensile forces created by leaf transpiration without any mechanical pumps. However, the high tension adversely induces a thermodynamically metastable state in sap water with negative pressure and gas bubbles are prone to be formed in xylem vessels. Cavitation easily breaks down continuous water columns and grows into embolization, which limits water transport through xylem vessels. Meanwhile, the repair process of embolization is closely related to water management and regulation of sap flow in plants. In this study, the cavitation and embolization phenomena of liquid water in vascular plants and a physical model system are experimentally and theoretically investigated in detail under in vivo and in vitro conditions. This study will not only shed light on the understanding of these multiphase flows under tension but also provide a clue to solve cavitation problems in micro-scale conduits and microfluidic network systems. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2008-0061991).

  15. Simulation and Experimental Study on Cavitating Water Jet Nozzle

    NASA Astrophysics Data System (ADS)

    Zhou, Wei; He, Kai; Cai, Jiannan; Hu, Shaojie; Li, Jiuhua; Du, Ruxu

    2017-01-01

    Cavitating water jet technology is a new kind of water jet technology with many advantages, such as energy-saving, efficient, environmentally-friendly and so on. Based on the numerical simulation and experimental verification in this paper, the research on cavitating nozzle has been carried out, which includes comparison of the cleaning ability of the cavitating jet and the ordinary jet, and comparison of cavitation effects of different structures of cavitating nozzles.

  16. Simultaneous pressure measurement and high-speed photography study of cavitation in a dynamically loaded journal bearing

    NASA Technical Reports Server (NTRS)

    Sun, D. C.; Brewe, David E.; Abel, Philip B.

    1994-01-01

    Cavitation of the oil film in a dynamically loaded journal bearing was studied using high-speed photography and pressure measurement simultaneously. Comparison of the visual and pressure data provided considerable insight into the occurrence and nonoccurrence of cavitation. It was found that (1) for the submerged journal bearing, cavitation typically occurred in the form of one bubble with the pressure in the cavitation bubble close to the absolute zero; and (2) for cavitation-producing operating conditions, cavitation did not always occur; with the oil film then supporting a tensile stress.

  17. Controlling cavitation-based image contrast in focused ultrasound histotripsy surgery.

    PubMed

    Allen, Steven P; Hall, Timothy L; Cain, Charles A; Hernandez-Garcia, Luis

    2015-01-01

    To develop MRI feedback for cavitation-based, focused ultrasound, tissue erosion surgery (histotripsy), we investigate image contrast generated by transient cavitation events. Changes in GRE image intensity are observed while balanced pairs of field gradients are varied in the presence of an acoustically driven cavitation event. The amplitude of the acoustic pulse and the timing between a cavitation event and the start of these gradient waveforms are also varied. The magnitudes and phases of the cavitation site are compared with those of control images. An echo-planar sequence is used to evaluate histotripsy lesions in ex vivo tissue. Cavitation events in water cause localized attenuation when acoustic pulses exceed a pressure threshold. Attenuation increases with increasing gradient amplitude and gradient lobe separation times and is isotropic with gradient direction. This attenuation also depends upon the relative timing between the cavitation event and the start of the balanced gradients. These factors can be used to control the appearance of attenuation while imaging ex vivo tissue. By controlling the timing between cavitation events and the imaging gradients, MR images can be made alternately sensitive or insensitive to cavitation. During therapy, these images can be used to isolate contrast generated by cavitation. © 2014 Wiley Periodicals, Inc.

  18. PASSIVE CAVITATION DETECTION DURING PULSED HIFU EXPOSURES OF EX VIVO TISSUES AND IN VIVO MOUSE PANCREATIC TUMORS

    PubMed Central

    Li, Tong; Chen, Hong; Khokhlova, Tatiana; Wang, Yak-Nam; Kreider, Wayne; He, Xuemei; Hwang, Joo Ha

    2014-01-01

    Pulsed high-intensity focused ultrasound (pHIFU) has been demonstrated to enhance vascular permeability, disrupt tumor barriers and enhance drug penetration into tumor tissue through acoustic cavitation. Monitoring of cavitation activity during pHIFU treatments and knowing the ultrasound pressure levels sufficient to reliably induce cavitation in a given tissue are therefore very important. Here, three metrics of cavitation activity induced by pHIFU and evaluated by confocal passive cavitation detection were introduced: cavitation probability, cavitation persistence and the level of the broadband acoustic emissions. These metrics were used to characterize cavitation activity in several ex vivo tissue types (bovine tongue and liver and porcine adipose tissue and kidney) and gel phantoms (polyacrylamide and agarose) at varying peak-rarefactional focal pressures (1–12 MPa) during the following pHIFU protocol: frequency 1.1 MHz, pulse duration 1 ms, pulse repetition frequency 1 Hz. To evaluate the relevance of the measurements in ex vivo tissue, cavitation metrics were also investigated and compared in the ex vivo and in vivo murine pancreatic tumors that develop spontaneously in transgenic KPC mice and closely recapitulate human disease in their morphology. The cavitation threshold, defined at 50 % cavitation probability, was found to vary broadly among the investigated tissues (within 2.5–10 MPa), depending mostly on the water-lipid ratio that characterizes the tissue composition. Cavitation persistence and the intensity of broadband emissions depended both on tissue structure and lipid concentration. Both the cavitation threshold and broadband noise emission level were similar between ex vivo and in vivo pancreatic tumor tissue. The largest difference between in vivo and ex vivo settings was found in the pattern of cavitation occurrence throughout pHIFU exposure: it was sporadic in vivo, but ex vivo it decreased rapidly and stopped over the first few pulses. Cavitation activity depended on the interplay between the destruction and circulation of cavitation nuclei, which are not only used up by HIFU treatment but also replenished or carried away by circulation in vivo. These findings are important for treatment planning and optimization in pHIFU-induced drug delivery, in particular for pancreatic tumors. PMID:24613635

  19. Cavitation nucleation in gelatin: Experiment and mechanism.

    PubMed

    Kang, Wonmo; Adnan, Ashfaq; O'Shaughnessy, Thomas; Bagchi, Amit

    2018-02-01

    Dynamic cavitation in soft materials is becoming increasingly relevant due to emerging medical implications such as the potential of cavitation-induced brain injury or cavitation created by therapeutic medical devices. However, the current understanding of dynamic cavitation in soft materials is still very limited, mainly due to lack of robust experimental techniques. To experimentally characterize cavitation nucleation under dynamic loading, we utilize a recently developed experimental instrument, the integrated drop tower system. This technique allows quantitative measurements of the critical acceleration (a cr ) that corresponds to cavitation nucleation while concurrently visualizing time evolution of cavitation. Our experimental results reveal that a cr increases with increasing concentration of gelatin in pure water. Interestingly, we have observed the distinctive transition from a sharp increase (pure water to 1% gelatin) to a much slower rate of increase (∼10× slower) between 1% and 7.5% gelatin. Theoretical cavitation criterion predicts the general trend of increasing a cr , but fails to explain the transition rates. As a likely mechanism, we consider concentration-dependent material properties and non-spherical cavitation nucleation sites, represented by pre-existing bubbles in gels, due to possible interplay between gelatin molecules and nucleation sites. This analysis shows that cavitation nucleation is very sensitive to the initial configuration of a bubble, i.e., a non-spherical bubble can significantly increase a cr . This conclusion matches well with the experimentally observed liquid-to-gel transition in the critical acceleration for cavitation nucleation. From a medical standpoint, understanding dynamic cavitation within soft materials, i.e., tissues, is important as there are both potential injury implications (blast-induced cavitation within the brain) as well as treatments utilizing the phenomena (lithotripsy). In this regard, the main results of the present work are (1) quantitative characterization of cavitation nucleation in gelatin samples as a function of gel concentration utilizing well-controlled mechanical impacts and (2) mechanistic understanding of complex coupling between cavitation and liquid-/solid-like material properties of gel. The new capabilities of testing soft gels, which can be tuned to mimic material properties of target organs, at high loading rate conditions and accurately predicting their cavitation behavior are an important step towards developing reliable cavitation criteria in the scope of their biomedical applications. Copyright © 2017 Acta Materialia Inc. All rights reserved.

  20. Intensification of esterification of non edible oil as sustainable feedstock using cavitational reactors.

    PubMed

    Mohod, Ashish V; Subudhi, Abhijeet S; Gogate, Parag R

    2017-05-01

    Using sustainable feed stock such as non-edible oil for the biodiesel production can be one of the cost effective approaches considering the ever growing interest towards renewable energy and problems in existing approaches for production. However, due to the high free fatty acid content, non-edible oils require considerable preprocessing before the actual transesterification reaction for biodiesel production. The present work focuses on intensification of the esterification reaction used as preprocessing step based on acoustic and hydrodynamic cavitation also presenting the comparison with the conventional approach. Karanja oil with initial acid value as 14.15mg of KOH/g of oil has been used as a sustainable feedstock. Effect of operating parameters such as molar ratio, catalyst loading, temperature and type of catalyst (sulfuric acid and Amberlyst-15) on the acid value reduction has been investigated. The maximum reduction in the acid value (final acid value as 2.7mg of KOH/g of oil) was obtained using acoustic cavitation at optimum molar ratio of oil to methanol as 1:5 and 2% sulfuric acid loading at ambient temperature. In the case of hydrodynamic cavitation, acid value reduced upto 4.2mg of KOH under optimized conditions of first stage processing. In the second stage esterification using hydrodynamic cavitation and conventional approach, the final acid value was 3.6 and 3.8mg of KOH/g of oil respectively. Energy requirement analysis for ultrasound and conventional approaches clearly established the superiority of the ultrasound based approach. The present study clearly demonstrated that significant intensification benefits can be obtained in terms of the reduction in the molar ratio and operating temperature for the case of acoustic cavitation as compared to the conventional approach with somewhat lower effects for the hydrodynamic cavitation. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Experimental evidence of inter-blade cavitation vortex development in Francis turbines at deep part load condition

    NASA Astrophysics Data System (ADS)

    Yamamoto, K.; Müller, A.; Favrel, A.; Avellan, F.

    2017-10-01

    Francis turbines are subject to various types of cavitation flow depending on the operating condition. To enable a smooth integration of the renewable energy sources, hydraulic machines are now increasingly required to extend their operating range, especially down to extremely low discharge conditions called deep part load operation. The inter-blade cavitation vortex is a typical cavitation phenomenon observed at deep part load operation. However, its dynamic characteristics are insufficiently understood today. In an objective of revealing its characteristics, the present study introduces a novel visualization technique with instrumented guide vanes embedding the visualization devices, providing unprecedented views on the inter-blade cavitation vortex. The binary image processing technique enables the successful evaluation of the inter-blade cavitation vortex in the images. As a result, it is shown that the probability of the inter-blade cavitation development is significantly high close to the runner hub. Furthermore, the mean vortex line is calculated and the vortex region is estimated in the three-dimensional domain for the comparison with numerical simulation results. In addition, the on-board pressure measurements on a runner blade is conducted, and the influence of the inter-blade vortex on the pressure field is investigated. The analysis suggests that the presence of the inter-blade vortex can magnify the amplitude of pressure fluctuations especially on the blade suction side. Furthermore, the wall pressure difference between pressure and suction sides of the blade features partially low or negative values near the hub at the discharge region where the inter-blade vortex develops. This negative pressure difference on the blade wall suggests the development of a backflow region caused by the flow separation near the hub, which is closely related to the development of the inter-blade vortex. The development of the backflow region is confirmed by the numerical simulation, and the physical mechanisms of the inter-blade vortex development is, furthermore, discussed.

  2. Effect of austempering temperature on cavitation behaviour of unalloyed ADI material

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dojcinovic, Marina; Eric, Olivera; Rajnovic, Dragan

    2013-08-15

    This paper provides an in-depth study and description of cavitation damage and microstructural changes in two types of unalloyed austempered ductile iron (ADI). ADI materials used were austempered at 300 and 400 °C having ausferrite microstructure with 16 and 31.4% of retained austenite, respectively. Metallographic examination was carried out to study the morphology of their cavitation-damaged surfaces. Cavitation damage was initiated at graphite nodules as well as in the interface between a graphite nodule and an ausferrite matrix. Furthermore, microcracking and ferrite/retained austenite morphology were proved to be of great importance for cavitation resistance. Mass loss rate revealed that ADImore » austempered at 400 °C has a higher cavitation resistance in water than ADI austempered at 300 °C. A higher amount of retained austenite in ADI austempered at 400 °C played an important role in increasing cavitation resistance. The good cavitation behaviour of ADI austempered at 400 °C was due to the matrix hardening by stress assisted phase transformation of retained austenite into martensite (SATRAM) phenomenon, as shown by X-ray diffraction analysis. - Highlights: • Cavitation rate of two ADI materials was tested. • ADI material with a lower hardness has had a lower cavitation rate. • The main reason is microstructural transformations during cavitation. • SATRAM phenomenon increases cavitation resistance.« less

  3. A Study of Cavitation Erosion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hiromu Isaka; Masatsugu Tsutsumi; Tadashi Shiraishi

    2002-07-01

    The authors performed experimental study for the purpose of the following two items from a viewpoint of cavitation erosion of a cylindrical orifice in view of a problem at the letdown orifice in PWR (Pressurized Water Reactor). 1. To get the critical cavitation parameter of the cylindrical orifice to establish the design criteria for prevention of cavitation erosion, and 2. to ascertain the erosion rate in such an eventuality that the cavitation erosion occurs with the orifice made of stainless steel with precipitation hardening (17-4-Cu hardening type stainless steel), so that we confirm the appropriateness of the design criteria. Regardingmore » the 1. item, we carried out the cavitation tests to get the critical cavitation parameters inside and downstream of the orifice. The test results showed that the cavitation parameter at inception is independent of the length or the diameter of the orifice. Moreover, the design criteria of cavitation erosion of cylindrical orifices have been established. Regarding the 2. item, we tested the erosion rate under high-pressure conditions. The cavitation erosion actually occurred in the cylindrical orifice at the tests that was strongly resemble to the erosion occurred at the plant. It will be seldom to reproduce resemble cavitation erosion in a cylindrical orifice with the hard material used at plants. We could establish the criteria for preventing the cavitation erosion from the test results. (authors)« less

  4. Probability of cavitation for single ultrasound pulses applied to tissues and tissue-mimicking materials

    PubMed Central

    Maxwell, Adam D.; Cain, Charles A.; Hall, Timothy L.; Fowlkes, J. Brian; Xu, Zhen

    2012-01-01

    In this article, the negative pressure values at which inertial cavitation consistently occurs in response to a single, 2-cycle, focused ultrasound pulse were measured in several media relevant to cavitation-based ultrasound therapy. The pulse was focused into a chamber containing one of the media, which included liquids, tissue-mimicking materials, and ex-vivo canine tissue. Focal waveforms were measured by two separate techniques using a fiber-optic hydrophone. Inertial cavitation was identified by high-speed photography in optically transparent media and an acoustic passive cavitation detector. The probability of cavitation (Pcav) for a single pulse as a function of peak negative pressure (p−) followed a sigmoid curve, with the probability approaching 1 when the pressure amplitude was sufficient. The statistical threshold (defined as Pcav = 0.5) was between p− = 26.0–30.0 MPa in all samples with a high water content, but varied between p− = 13.7 to > 36 MPa for other media. A model for radial cavitation bubble dynamics was employed to evaluate the behavior of cavitation nuclei at these pressure levels. A single bubble nucleus with an inertial cavitation threshold of p− = 28.2 MPa was estimated to have a 2.5 nm radius in distilled water. These data may be valuable for cavitation-based ultrasound therapy to predict the likelihood of cavitation at different pressure levels and dimensions of cavitation-induced lesions in tissue. PMID:23380152

  5. A New Active Cavitation Mapping Technique for Pulsed HIFU Applications – Bubble Doppler

    PubMed Central

    Li, Tong; Khokhlova, Tatiana; Sapozhnikov, Oleg; Hwang, Joo Ha; Sapozhnikov, Oleg; O’Donnell, Matthew

    2015-01-01

    In this work, a new active cavitation mapping technique for pulsed high-intensity focused ultrasound (pHIFU) applications termed bubble Doppler is proposed and its feasibility tested in tissue-mimicking gel phantoms. pHIFU therapy uses short pulses, delivered at low pulse repetition frequency, to cause transient bubble activity that has been shown to enhance drug and gene delivery to tissues. The current gold standard for detecting and monitoring cavitation activity during pHIFU treatments is passive cavitation detection (PCD), which provides minimal information on the spatial distribution of the bubbles. B-mode imaging can detect hyperecho formation, but has very limited sensitivity, especially to small, transient microbubbles. The bubble Doppler method proposed here is based on a fusion of the adaptations of three Doppler techniques that had been previously developed for imaging of ultrasound contrast agents – color Doppler, pulse inversion Doppler, and decorrelation Doppler. Doppler ensemble pulses were interleaved with therapeutic pHIFU pulses using three different pulse sequences and standard Doppler processing was applied to the received echoes. The information yielded by each of the techniques on the distribution and characteristics of pHIFU-induced cavitation bubbles was evaluated separately, and found to be complementary. The unified approach - bubble Doppler – was then proposed to both spatially map the presence of transient bubbles and to estimate their sizes and the degree of nonlinearity. PMID:25265178

  6. Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging

    NASA Astrophysics Data System (ADS)

    Chu, Po-Chun; Chai, Wen-Yen; Tsai, Chih-Hung; Kang, Shih-Tsung; Yeh, Chih-Kuang; Liu, Hao-Li

    2016-09-01

    Focused ultrasound (FUS) with microbubbles can temporally open the blood-brain barrier (BBB), and the cavitation activities of microbubbles play a key role in the BBB-opening process. Previous attempts used contrast-enhanced magnetic resonance imaging (CE-MRI) to correlate the mechanical index (MI) with the scale of BBB-opening, but MI only partially gauged acoustic activities, and CE-MRI did not fully explore correlations of pharmacodynamic/pharmacokinetic behaviors. Recently, the cavitation index (CI) has been derived to serve as an indicator of microbubble-ultrasound stable cavitation, and may also serve as a valid indicator to gauge the level of FUS-induced BBB opening. This study investigates the feasibility of gauging FUS-induced BBB opened level via the two indexes, MI and CI, through dynamic contrast-enhanced (DCE)-MRI analysis as well as passive cavitation detection (PCD) analysis. Pharmacodynamic/pharmacokinetic parameters derived from DCE-MRI were characterized to identify the scale of FUS-induced BBB opening. Our results demonstrated that DCE-MRI can successfully access pharmacodynamic/pharmacokinetic BBB-opened behavior, and was highly correlated both with MI and CI, implying the feasibility in using these two indices to gauge the scale of FUS-induced BBB opening. The proposed finding may facilitate the design toward using focused ultrasound as a safe and reliable noninvasive CNS drug delivery.

  7. A new methodology to prepare ceramic-organic composite coatings with good cavitation erosion resistance.

    PubMed

    Deng, Wen; Hou, Guoliang; Li, Shuangjian; Han, Jiesheng; Zhao, Xiaoqin; Liu, Xia; An, Yulong; Zhou, Huidi; Chen, Jianmin

    2018-06-01

    A simple, scalable and economical method was proposed to obtain ceramic-organic composite coating with excellent comprehensive properties include hardness, toughness, elastic recovery, lamellar interfacial bonding and anti-cavitation erosion: introducing epoxy resin into the pores and micro-cracks of plasma sprayed ceramic coating. The results indicate that the epoxy resin was successfully penetrated into the whole ceramic coating and filled almost all defects by vacuum impregnation, which greatly enhanced its compactness and mechanical properties. The bonding strength between top coating and metal interlayer significantly increased from 17.3 MPa to 53.0 MPa, and the hardness (H) of top coating greatly increased from 11.07 GPa to 23.57 GPa. Besides, the value of H 3 /E 2 also increased from 0.06 GPa to 0.15 GPa, meaning the toughness of ceramic coating had been obviously improved. The pure ceramic coating had been punctured only after 4 h of cavitation test. However, the resin with high elasticity and toughness can effectively absorb impact energy, prevent cracks propagation and delay splats spallation during the cavitation erosion process. The novel composite coating displayed far better cavitation erosion resistance than pure ceramic coating, and it was still intact after 10 h of test. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging.

    PubMed

    Chu, Po-Chun; Chai, Wen-Yen; Tsai, Chih-Hung; Kang, Shih-Tsung; Yeh, Chih-Kuang; Liu, Hao-Li

    2016-09-15

    Focused ultrasound (FUS) with microbubbles can temporally open the blood-brain barrier (BBB), and the cavitation activities of microbubbles play a key role in the BBB-opening process. Previous attempts used contrast-enhanced magnetic resonance imaging (CE-MRI) to correlate the mechanical index (MI) with the scale of BBB-opening, but MI only partially gauged acoustic activities, and CE-MRI did not fully explore correlations of pharmacodynamic/pharmacokinetic behaviors. Recently, the cavitation index (CI) has been derived to serve as an indicator of microbubble-ultrasound stable cavitation, and may also serve as a valid indicator to gauge the level of FUS-induced BBB opening. This study investigates the feasibility of gauging FUS-induced BBB opened level via the two indexes, MI and CI, through dynamic contrast-enhanced (DCE)-MRI analysis as well as passive cavitation detection (PCD) analysis. Pharmacodynamic/pharmacokinetic parameters derived from DCE-MRI were characterized to identify the scale of FUS-induced BBB opening. Our results demonstrated that DCE-MRI can successfully access pharmacodynamic/pharmacokinetic BBB-opened behavior, and was highly correlated both with MI and CI, implying the feasibility in using these two indices to gauge the scale of FUS-induced BBB opening. The proposed finding may facilitate the design toward using focused ultrasound as a safe and reliable noninvasive CNS drug delivery.

  9. Pressure in a cavity under unsteady conditions

    NASA Astrophysics Data System (ADS)

    Ershov, N. S.

    A transparent Venturi tube equipped with an inductive sensor and an inlet pulser has been used to measure pressure inside a cavity, both in cold and hot water. It is found that at frequencies up to 25 Hz, pressure inside the cavity remains constant and is equal to the steam elasticity over cold and hot water. It is suggested that evaporation and condensation are controlling, rather than accompanying, processes in the dynamics of cavitation. Implications of the results for cavitation pumps are briefly discussed.

  10. Cavitation during the protein misfolding cyclic amplification (PMCA) method – The trigger for de novo prion generation?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haigh, Cathryn L., E-mail: chaigh@unimelb.edu.au; Drew, Simon C., E-mail: sdrew@unimelb.edu.au

    The protein misfolding cyclic amplification (PMCA) technique has become a widely-adopted method for amplifying minute amounts of the infectious conformer of the prion protein (PrP). PMCA involves repeated cycles of 20 kHz sonication and incubation, during which the infectious conformer seeds the conversion of normally folded protein by a templating interaction. Recently, it has proved possible to create an infectious PrP conformer without the need for an infectious seed, by including RNA and the phospholipid POPG as essential cofactors during PMCA. The mechanism underpinning this de novo prion formation remains unknown. In this study, we first establish by spin trapping methodsmore » that cavitation bubbles formed during PMCA provide a radical-rich environment. Using a substrate preparation comparable to that employed in studies of de novo prion formation, we demonstrate by immuno-spin trapping that PrP- and RNA-centered radicals are generated during sonication, in addition to PrP-RNA cross-links. We further show that serial PMCA produces protease-resistant PrP that is oxidatively modified. We suggest a unique confluence of structural (membrane-mimetic hydrophobic/hydrophilic bubble interface) and chemical (ROS) effects underlie the phenomenon of de novo prion formation by PMCA, and that these effects have meaningful biological counterparts of possible relevance to spontaneous prion formation in vivo. - Highlights: • Sonication during PMCA generates free radicals at the surface of cavitation bubbles. • PrP-centered and RNA-centered radicals are formed in addition to PrP-RNA adducts. • De novo prions may result from ROS and structural constraints during cavitation.« less

  11. Ultrasound detection of cavitation as a phenomenon common to intervention devices causing tissue ablation

    NASA Astrophysics Data System (ADS)

    Bach, David S.; Armstrong, William F.; Erbel, Raimund; Ellis, Stephen G.; Sousa, Joao; Rosenschein, Uri

    1992-08-01

    Cavitation previously has been observed in association with ultrasonic angioplasty and high- frequency rotational atherectomy. This study evaluates the production of cavitation accompanying the use of several catheter-based devices under development or in current use in the practice of interventional cardiology. Catheters were examined in an in vitro model, and cavitation was evaluated using standard ultrasound imaging equipment. Cavitation was detected with each of the devices that effects tissue ablation, but not tissue resection. Devices produced characteristic patterns of cavitation dependent on the mode of energy release of the device. The size, but not the intensity, of the cavitation effect was proportional to the energy output of the devices. The precise role of cavitation in the mechanism of tissue ablation remains uncertain.

  12. Numerical simulation of cavitation and atomization using a fully compressible three-phase model

    NASA Astrophysics Data System (ADS)

    Mithun, Murali-Girija; Koukouvinis, Phoevos; Gavaises, Manolis

    2018-06-01

    The aim of this paper is to present a fully compressible three-phase (liquid, vapor, and air) model and its application to the simulation of in-nozzle cavitation effects on liquid atomization. The model employs a combination of the homogeneous equilibrium barotropic cavitation model with an implicit sharp interface capturing volume of fluid (VOF) approximation. The numerical predictions are validated against the experimental results obtained for injection of water into the air from a step nozzle, which is designed to produce asymmetric cavitation along its two sides. Simulations are performed for three injection pressures, corresponding to three different cavitation regimes, referred to as cavitation inception, developing cavitation, and hydraulic flip. Model validation is achieved by qualitative comparison of the cavitation, spray pattern, and spray cone angles. The flow turbulence in this study is resolved using the large-eddy simulation approach. The simulation results indicate that the major parameters that influence the primary atomization are cavitation, liquid turbulence, and, to a smaller extent, the Rayleigh-Taylor and Kelvin-Helmholtz aerodynamic instabilities developing on the liquid-air interface. Moreover, the simulations performed indicate that periodic entrainment of air into the nozzle occurs at intermediate cavitation numbers, corresponding to developing cavitation (as opposed to incipient and fully developed cavitation regimes); this transient effect causes a periodic shedding of the cavitation and air clouds and contributes to improved primary atomization. Finally, the cone angle of the spray is found to increase with increased injection pressure but drops drastically when hydraulic flip occurs, in agreement with the relevant experiments.

  13. Mechanisms of mechanical heart valve cavitation: investigation using a tilting disk valve model.

    PubMed

    He, Z; Xi, B; Zhu, K; Hwang, N H

    2001-09-01

    The induction of mechanical heart valve (MHV) cavitation was investigated using a 27 mm Medtronic Hall (MH27) tilting disk valve. The MH27 valve was mounted in the mitral position of a simulating pulse flow system, and stroboscopic lighting used to visualize cavitation bubbles on the occluder inflow surface at the instant of valve closure. MHV cavitation was monitored using a digital camera with 0.04 mm/pixel resolution sufficient to render the tiny bubbles clearly visible on the computer monitor screen. Cavitation on MH27 valve was classified as five types according to the time, site and shape of the cavitation bubbles. Valve cavitation occurred at the instant of occluder impact with the valve seat at closing. The impact motion was subdivided into three temporal phases: (i) squeezing flow; (ii) elastic collision; and (iii) leaflet rebound. MHV cavitation caused by vortices was found to be initiated by the squeezing jet and/or by the transvalvular leakage jets. By using a tension wave which swept across the occluder surface immediately upon elastic impact, nuclei in the vortex core were expanded to form cavitation bubbles. Analysis of the shape and location of the cavitation bubbles permitted a better understanding of MHV cavitation mechanisms, based on the fluid dynamics of jet vortex and tension wave propagations.

  14. Cavitation in flow through a micro-orifice inside a silicon microchannel

    NASA Astrophysics Data System (ADS)

    Mishra, Chandan; Peles, Yoav

    2005-01-01

    Hydrodynamic cavitation in flows through a micro-orifice entrenched in a microchannel has been detected and experimentally investigated. Microfabrication techniques have been employed to design and develop a microfluidic device containing an 11.5μm wide micro-orifice inside a 100.2μm wide and 101.3μm deep microchannel. The flow of de-ionized water through the micro-orifice reveals the presence of multifarious cavitating flow regimes. This investigation divulges both similarities and differences between cavitation in micro-orifices and cavitation in their macroscale counterparts. The low incipient cavitation number obtained from the current experiments suggests a dominant size scale effect. Choking cavitation is observed to be independent of any pressure or velocity scale effects. However, choking is significantly influenced by the small stream nuclei residence time at such scales. Flow rate choking leads to the establishment of a stationary cavity. Large flow and cavitation hysteresis have been detected at the microscale leading to very high desinent cavitation numbers. The rapid transition from incipient bubbles to choking cavitation and subsequent supercavitation suggests the presence of radically different flow patterns at the microscale. Supercavitation results in a thick cavity, which extends throughout the microchannel, and is encompassed by the liquid. Cavitation at the microscale is expected to considerably influence the design of innovative high-speed microfluidic systems.

  15. High-speed motion picture camera experiments of cavitation in dynamically loaded journal bearings

    NASA Technical Reports Server (NTRS)

    Jacobson, B. O.; Hamrock, B. J.

    1982-01-01

    A high-speed camera was used to investigate cavitation in dynamically loaded journal bearings. The length-diameter ratio of the bearing, the speeds of the shaft and bearing, the surface material of the shaft, and the static and dynamic eccentricity of the bearing were varied. The results reveal not only the appearance of gas cavitation, but also the development of previously unsuspected vapor cavitation. It was found that gas cavitation increases with time until, after many hundreds of pressure cycles, there is a constant amount of gas kept in the cavitation zone of the bearing. The gas can have pressures of many times the atmospheric pressure. Vapor cavitation bubbles, on the other hand, collapse at pressures lower than the atmospheric pressure and cannot be transported through a high-pressure zone, nor does the amount of vapor cavitation in a bearing increase with time. Analysis is given to support the experimental findings for both gas and vapor cavitation.

  16. Cavitation onset caused by acceleration

    PubMed Central

    Pan, Zhao; Kiyama, Akihito; Tagawa, Yoshiyuki; Daily, David J.; Thomson, Scott L.; Hurd, Randy

    2017-01-01

    Striking the top of a liquid-filled bottle can shatter the bottom. An intuitive interpretation of this event might label an impulsive force as the culprit in this fracturing phenomenon. However, high-speed photography reveals the formation and collapse of tiny bubbles near the bottom before fracture. This observation indicates that the damaging phenomenon of cavitation is at fault. Cavitation is well known for causing damage in various applications including pipes and ship propellers, making accurate prediction of cavitation onset vital in several industries. However, the conventional cavitation number as a function of velocity incorrectly predicts the cavitation onset caused by acceleration. This unexplained discrepancy leads to the derivation of an alternative dimensionless term from the equation of motion, predicting cavitation as a function of acceleration and fluid depth rather than velocity. Two independent research groups in different countries have tested this theory; separate series of experiments confirm that an alternative cavitation number, presented in this paper, defines the universal criteria for the onset of acceleration-induced cavitation. PMID:28739956

  17. Cavitation onset caused by acceleration.

    PubMed

    Pan, Zhao; Kiyama, Akihito; Tagawa, Yoshiyuki; Daily, David J; Thomson, Scott L; Hurd, Randy; Truscott, Tadd T

    2017-07-24

    Striking the top of a liquid-filled bottle can shatter the bottom. An intuitive interpretation of this event might label an impulsive force as the culprit in this fracturing phenomenon. However, high-speed photography reveals the formation and collapse of tiny bubbles near the bottom before fracture. This observation indicates that the damaging phenomenon of cavitation is at fault. Cavitation is well known for causing damage in various applications including pipes and ship propellers, making accurate prediction of cavitation onset vital in several industries. However, the conventional cavitation number as a function of velocity incorrectly predicts the cavitation onset caused by acceleration. This unexplained discrepancy leads to the derivation of an alternative dimensionless term from the equation of motion, predicting cavitation as a function of acceleration and fluid depth rather than velocity. Two independent research groups in different countries have tested this theory; separate series of experiments confirm that an alternative cavitation number, presented in this paper, defines the universal criteria for the onset of acceleration-induced cavitation.

  18. Cavitation onset caused by acceleration

    NASA Astrophysics Data System (ADS)

    Pan, Zhao; Kiyama, Akihito; Tagawa, Yoshiyuki; Daily, David J.; Thomson, Scott L.; Hurd, Randy; Truscott, Tadd T.

    2017-08-01

    Striking the top of a liquid-filled bottle can shatter the bottom. An intuitive interpretation of this event might label an impulsive force as the culprit in this fracturing phenomenon. However, high-speed photography reveals the formation and collapse of tiny bubbles near the bottom before fracture. This observation indicates that the damaging phenomenon of cavitation is at fault. Cavitation is well known for causing damage in various applications including pipes and ship propellers, making accurate prediction of cavitation onset vital in several industries. However, the conventional cavitation number as a function of velocity incorrectly predicts the cavitation onset caused by acceleration. This unexplained discrepancy leads to the derivation of an alternative dimensionless term from the equation of motion, predicting cavitation as a function of acceleration and fluid depth rather than velocity. Two independent research groups in different countries have tested this theory; separate series of experiments confirm that an alternative cavitation number, presented in this paper, defines the universal criteria for the onset of acceleration-induced cavitation.

  19. Experiences with the hydraulic design of the high specific speed Francis turbine

    NASA Astrophysics Data System (ADS)

    Obrovsky, J.; Zouhar, J.

    2014-03-01

    The high specific speed Francis turbine is still suitable alternative for refurbishment of older hydro power plants with lower heads and worse cavitation conditions. In the paper the design process of such kind of turbine together with the results comparison of homological model tests performed in hydraulic laboratory of ČKD Blansko Engineering is introduced. The turbine runner was designed using the optimization algorithm and considering the high specific speed hydraulic profile. It means that hydraulic profiles of the spiral case, the distributor and the draft tube were used from a Kaplan turbine. The optimization was done as the automatic cycle and was based on a simplex optimization method as well as on a genetic algorithm. The number of blades is shown as the parameter which changes the resulting specific speed of the turbine between ns=425 to 455 together with the cavitation characteristics. Minimizing of cavitation on the blade surface as well as on the inlet edge of the runner blade was taken into account during the design process. The results of CFD analyses as well as the model tests are mentioned in the paper.

  20. An acoustofluidic micromixer via bubble inception and cavitation from microchannel sidewalls.

    PubMed

    Ozcelik, Adem; Ahmed, Daniel; Xie, Yuliang; Nama, Nitesh; Qu, Zhiguo; Nawaz, Ahmad Ahsan; Huang, Tony Jun

    2014-05-20

    During the deep reactive ion etching process, the sidewalls of a silicon mold feature rough wavy structures, which can be transferred onto a polydimethylsiloxane (PDMS) microchannel through the soft lithography technique. In this article, we utilized the wavy structures of PDMS microchannel sidewalls to initiate and cavitate bubbles in the presence of acoustic waves. Through bubble cavitation, this acoustofluidic approach demonstrates fast, effective mixing in microfluidics. We characterized its performance by using viscous fluids such as poly(ethylene glycol) (PEG). When two PEG solutions with a resultant viscosity 54.9 times higher than that of water were used, the mixing efficiency was found to be 0.92, indicating excellent, homogeneous mixing. The acoustofluidic micromixer presented here has the advantages of simple fabrication, easy integration, and capability to mix high-viscosity fluids (Reynolds number: ~0.01) in less than 100 ms.

  1. Numerical 3D flow simulation of attached cavitation structures at ultrasonic horn tips and statistical evaluation of flow aggressiveness via load collectives

    NASA Astrophysics Data System (ADS)

    Mottyll, S.; Skoda, R.

    2015-12-01

    A compressible inviscid flow solver with barotropic cavitation model is applied to two different ultrasonic horn set-ups and compared to hydrophone, shadowgraphy as well as erosion test data. The statistical analysis of single collapse events in wall-adjacent flow regions allows the determination of the flow aggressiveness via load collectives (cumulative event rate vs collapse pressure), which show an exponential decrease in agreement to studies on hydrodynamic cavitation [1]. A post-processing projection of event rate and collapse pressure on a reference grid reduces the grid dependency significantly. In order to evaluate the erosion-sensitive areas a statistical analysis of transient wall loads is utilised. Predicted erosion sensitive areas as well as temporal pressure and vapour volume evolution are in good agreement to the experimental data.

  2. Inside a Collapsing Bubble: Sonoluminescence and the Conditions During Cavitation

    NASA Astrophysics Data System (ADS)

    Suslick, Kenneth S.; Flannigan, David J.

    2008-05-01

    Acoustic cavitation, the growth and rapid collapse of bubbles in a liquid irradiated with ultrasound, is a unique source of energy for driving chemical reactions with sound, a process known as sonochemistry. Another consequence of acoustic cavitation is the emission of light [sonoluminescence (SL)]. Spectroscopic analyses of SL from single bubbles as well as a cloud of bubbles have revealed line and band emission, as well as an underlying continuum arising from a plasma. Application of spectrometric methods of pyrometry as well as tools of plasma diagnostics to relative line intensities, profiles, and peak positions have allowed the determination of intracavity temperatures and pressures. These studies have shown that extraordinary conditions (temperatures up to 20,000 K; pressures of several thousand bar; and heating and cooling rates of >1012 K s1) are generated within an otherwise cold liquid.

  3. Passive cavitation detection during pulsed HIFU exposures of ex vivo tissues and in vivo mouse pancreatic tumors.

    PubMed

    Li, Tong; Chen, Hong; Khokhlova, Tatiana; Wang, Yak-Nam; Kreider, Wayne; He, Xuemei; Hwang, Joo Ha

    2014-07-01

    Pulsed high-intensity focused ultrasound (pHIFU) has been shown to enhance vascular permeability, disrupt tumor barriers and enhance drug penetration into tumor tissue through acoustic cavitation. Monitoring of cavitation activity during pHIFU treatments and knowing the ultrasound pressure levels sufficient to reliably induce cavitation in a given tissue are therefore very important. Here, three metrics of cavitation activity induced by pHIFU and evaluated by confocal passive cavitation detection were introduced: cavitation probability, cavitation persistence and the level of the broadband acoustic emissions. These metrics were used to characterize cavitation activity in several ex vivo tissue types (bovine tongue and liver and porcine adipose tissue and kidney) and gel phantoms (polyacrylamide and agarose) at varying peak-rare factional focal pressures (1-12 MPa) during the following pHIFU protocol: frequency 1.1 MHz, pulse duration 1 ms and pulse repetition frequency 1 Hz. To evaluate the relevance of the measurements in ex vivo tissue, cavitation metrics were also investigated and compared in the ex vivo and in vivo murine pancreatic tumors that develop spontaneously in transgenic KrasLSL.G12 D/+; p53 R172 H/+; PdxCretg/+ (KPC) mice and closely re-capitulate human disease in their morphology. The cavitation threshold, defined at 50% cavitation probability, was found to vary broadly among the investigated tissues (within 2.5-10 MPa), depending mostly on the water-lipid ratio that characterizes the tissue composition. Cavitation persistence and the intensity of broadband emissions depended both on tissue structure and lipid concentration. Both the cavitation threshold and broadband noise emission level were similar between ex vivo and in vivo pancreatic tumor tissue. The largest difference between in vivo and ex vivo settings was found in the pattern of cavitation occurrence throughout pHIFU exposure: it was sporadic in vivo, but it decreased rapidly and stopped over the first few pulses ex vivo. Cavitation activity depended on the interplay between the destruction and circulation of cavitation nuclei, which are not only used up by HIFU treatment but also replenished or carried away by circulation in vivo. These findings are important for treatment planning and optimization in pHIFU-induced drug delivery, in particular for pancreatic tumors. Published by Elsevier Inc.

  4. Numerical Study of the Transition Between Reentrant Jet and Twin Vortex Flow Regimes in Ventilated Cavitation

    NASA Astrophysics Data System (ADS)

    Adama Maiga, Mahamadou; Coutier-Delgosha, Olivier; Bois, Gérard

    2018-06-01

    Contrary to natural cavitation, ventilated cavitation is controllable and is not harmful. It is particularly used to reduce the drag of the hydraulic vehicles. The ventilated cavitation is characterized by various gas regimes. The mechanisms of ventilated cavitation are investigated in the present work with CFD based on a 2D solver. The attention is especially focused on the transition between the reentrant jet and twin vortex regimes. The results confirm that the product of ventilated cavitation number and Froude number is lower than 1 (σ c Fr < 1) in the twin vortex regime, while it is higher than 1 (σ c Fr > 1) in the reentrant jet regime, as reported in the literature. Further analysis shows that ventilated cavitation is significantly influenced by the natural cavitation number.

  5. Precise spatial control of cavitation erosion in a vessel phantom by using an ultrasonic standing wave.

    PubMed

    Shi, Aiwei; Huang, Peixuan; Guo, Shifang; Zhao, Lu; Jia, Yingjie; Zong, Yujin; Wan, Mingxi

    2016-07-01

    In atherosclerotic inducement in animal models, the conventionally used balloon injury is invasive, produces excessive vessel injuries at unpredictable locations and is inconvenient in arterioles. Fortunately, cavitation erosion, which plays an important role in therapeutic ultrasound in blood vessels, has the potential to induce atherosclerosis noninvasively at predictable sites. In this study, precise spatial control of cavitation erosion for superficial lesions in a vessel phantom was realised by using an ultrasonic standing wave (USW) with the participation of cavitation nuclei and medium-intensity ultrasound pulses. The superficial vessel erosions were restricted between adjacent pressure nodes, which were 0.87 mm apart in the USW field of 1 MHz. The erosion positions could be shifted along the vessel by nodal modulation under a submillimetre-scale accuracy without moving the ultrasound transducers. Moreover, the cavitation erosion of the proximal or distal wall could be determined by the types of cavitation nuclei and their corresponding cavitation pulses, i.e., phase-change microbubbles with cavitation pulses of 5 MHz and SonoVue microbubbles with cavitation pulses of 1 MHz. Effects of acoustic parameters of the cavitation pulses on the cavitation erosions were investigated. The flow conditions in the experiments were considered and discussed. Compared to only using travelling waves, the proposed method in this paper improves the controllability of the cavitation erosion and reduces the erosion depth, providing a more suitable approach for vessel endothelial injury while avoiding haemorrhage. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Cavitation noise studies on marine propellers

    NASA Astrophysics Data System (ADS)

    Sharma, S. D.; Mani, K.; Arakeri, V. H.

    1990-04-01

    Experimental observations are described of cavitation inception and noise from five model propellers, three basic and two modified, tested in the open jet section of the Indian Institute of Science high-speed water tunnel facility. Extensive experiments on the three basic propellers of different design, which included visualization of cavitation and measurements of noise, showed that the dominant type of cavitation was in the form of tip vortex cavitation, accompanied by leading edge suction side sheet cavitation in its close vicinity, and the resultant noise depended on parameters such as the advance coefficient, the cavitation number, and the propeller geometry. Of these, advance coefficient was found to have the maximum influence not only on cavitation noise but also on the inception of cavitation. Noise levels and frequencies of spectra obtained from all the three basic propellers at conditions near inception and different advance coefficient values, when plotted in the normalized form as suggested by Blake, resulted in a universal spectrum which would be useful for predicting cavitation noise at prototype scales when a limited extent of cavitation is expected in the same form as observed on the present models. In an attempt to delay the onset of tip vortex cavitation, the blades of two of the three basic propellers were modified by drilling small holes in the tip and leading edge areas. Studies on the modified propellers showed that the effectiveness of the blade modification was apparently stronger at low advance coefficient values and depended on the blade sectional profile. Measurements of cavitation noise indicated that the modification also improved the acoustic performance of the propellers as it resulted in a complete attenuation of the low-frequency spectral peaks, which were prominent with the basic propellers. In addition to the above studies, which were conducted under uniform flow conditions, one of the basic propellers was tested in the simulated wake of a typical single screw ship. The wake was simulated by using a wire screen technique. Observations of cavitation and measurement of noise clearly showed that the presence of the wake had a strong influence on the propeller cavitation and noise performance. Cavitation was found to be of the cloud type, which generated very intense noise compared to that generated by tip vortex cavitation along with leading edge suction side sheet cavitation in the uniform flow conditions. The noise spectra obtained with wake simulation also are presented in a normalized form to be of general utility.

  7. Tip-leakage cavitation in the clearance of a 2D hydrofoil with fillets: high-speed visualization and PIV/PTV measurements

    NASA Astrophysics Data System (ADS)

    Zapryagaev, Ivan I.; Timoshevskiy, Mikhail V.; Pervunin, Konstantin S.

    2017-09-01

    Tip-clearance cavitation is one of the most aggressive forms of cavitation as it can cause surface erosion of hydraulic machinery elements and, as a result, their fatigue damage and disturb designed operating conditions. At present, the literature lacks for detailed experimental data on the inception and development of this type of cavitation at various flow conditions. In the paper, a tip-leakage cavitation occurring in the clearance between an end face of a 2D hydrofoil (a scaled-down model of guide vanes (GV) of a Francis turbine) and a transparent wall of the test section was studied. The experiments were carried out for different cavitating regimes on the cavitation number and two attack angles of 3° and 9°, with the gap size (tip clearance width) varied in the range from 0.4 to 0.8 mm. In order to determine the cavitation inception conditions and investigate the dynamics of the tip-leakage cavitation, a high-speed visualization was applied. A modified PIV/PTV technique with a diverging laser beam instead of a laser light sheet was used to measure the mean velocity distributions within the gap. It was shown that the cavitation pattern on the suction side of the GV model impacts the dynamics of the leakage flow in the gap but does not affect the sheet cavity formed close to the foil leading edge in the clearance as well as its size and dynamics. When the gap size is increased, the tip-leakage cavitation initiates at higher cavitation numbers or, in other words, conditions for the cavitation occurrence become more favorable.

  8. Dental caries: a dynamic disease process.

    PubMed

    Featherstone, J D B

    2008-09-01

    Abstract Dental caries is a transmissible bacterial disease process caused by acids from bacterial metabolism diffusing into enamel and dentine and dissolving the mineral. The bacteria responsible produce organic acids as a by-product of their metabolism of fermentable carbohydrates. The caries process is a continuum resulting from many cycles of demineralization and remineralization. Demineralization begins at the atomic level at the crystal surface inside the enamel or dentine and can continue unless halted with the end-point being cavitation. There are many possibilities to intervene in this continuing process to arrest or reverse the progress of the lesion. Remineralization is the natural repair process for non-cavitated lesions, and relies on calcium and phosphate ions assisted by fluoride to rebuild a new surface on existing crystal remnants in subsurface lesions remaining after demineralization. These remineralized crystals are acid resistant, being much less soluble than the original mineral.

  9. Cavitation in a metallic liquid: Homogeneous nucleation and growth of nanovoids

    NASA Astrophysics Data System (ADS)

    Cai, Y.; Wu, H. A.; Luo, S. N.

    2014-06-01

    Large-scale molecular dynamics (MD) simulations are performed to investigate homogeneous nucleation and growth of nanovoids during cavitation in liquid Cu. We characterize in detail the atomistic cavitation processes by following the temporal evolution of cavities or voids, analyze the nucleation behavior with the mean first-passage time (MFPT) and survival probability (SP) methods, and discuss the results against classical nucleation theory (CNT), the Tolman equation for surface energy, independent calculation of surface tension via integrating the stress profiles, the Johnson-Mehl-Avrami (JMA) growth law, and the power law for nucleus size distributions. Cavitation in this representative metallic liquid is a high energy barrier Poisson processes, and the steady-state nucleation rates obtained from statistical runs with the MFPT and SP methods are in agreement. The MFPT method also yields the critical nucleus size and the Zeldovich factor. Fitting with the Tolman's equation to the MD simulations yields the surface energy of a planar interface (˜0.9 J {m}^{-2}) and the Tolman length (0.4-0.5 Å), and those values are in accord with those from integrating the stress profiles of a planar interface. Independent CNT predictions of the nucleation rate (1033 - 34 s-1 m-3) and critical size (3-4 Å in radius) are in agreement with the MFPT and SP results. The JMA law can reasonably describe the nucleation and growth process. The size distribution of subcritical nuclei appears to follow a power law with an exponent decreasing with increasing tension owing to coupled nucleation and growth, and that of the supercritical nuclei becomes flattened during further stress relaxation due to void coalescence.

  10. Cavitation in a metallic liquid: homogeneous nucleation and growth of nanovoids.

    PubMed

    Cai, Y; Wu, H A; Luo, S N

    2014-06-07

    Large-scale molecular dynamics (MD) simulations are performed to investigate homogeneous nucleation and growth of nanovoids during cavitation in liquid Cu. We characterize in detail the atomistic cavitation processes by following the temporal evolution of cavities or voids, analyze the nucleation behavior with the mean first-passage time (MFPT) and survival probability (SP) methods, and discuss the results against classical nucleation theory (CNT), the Tolman equation for surface energy, independent calculation of surface tension via integrating the stress profiles, the Johnson-Mehl-Avrami (JMA) growth law, and the power law for nucleus size distributions. Cavitation in this representative metallic liquid is a high energy barrier Poisson processes, and the steady-state nucleation rates obtained from statistical runs with the MFPT and SP methods are in agreement. The MFPT method also yields the critical nucleus size and the Zeldovich factor. Fitting with the Tolman's equation to the MD simulations yields the surface energy of a planar interface (~0.9 J m⁻²) and the Tolman length (0.4-0.5 Å), and those values are in accord with those from integrating the stress profiles of a planar interface. Independent CNT predictions of the nucleation rate (10(33 - 34) s(-1) m(-3)) and critical size (3-4 Å in radius) are in agreement with the MFPT and SP results. The JMA law can reasonably describe the nucleation and growth process. The size distribution of subcritical nuclei appears to follow a power law with an exponent decreasing with increasing tension owing to coupled nucleation and growth, and that of the supercritical nuclei becomes flattened during further stress relaxation due to void coalescence.

  11. Cavitation in a metallic liquid: Homogeneous nucleation and growth of nanovoids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cai, Y.; The Peac Institute of Multiscale Sciences, Chengdu, Sichuan 610207; Wu, H. A., E-mail: wuha@ustc.edu.cn

    2014-06-07

    Large-scale molecular dynamics (MD) simulations are performed to investigate homogeneous nucleation and growth of nanovoids during cavitation in liquid Cu. We characterize in detail the atomistic cavitation processes by following the temporal evolution of cavities or voids, analyze the nucleation behavior with the mean first-passage time (MFPT) and survival probability (SP) methods, and discuss the results against classical nucleation theory (CNT), the Tolman equation for surface energy, independent calculation of surface tension via integrating the stress profiles, the Johnson-Mehl-Avrami (JMA) growth law, and the power law for nucleus size distributions. Cavitation in this representative metallic liquid is a high energymore » barrier Poisson processes, and the steady-state nucleation rates obtained from statistical runs with the MFPT and SP methods are in agreement. The MFPT method also yields the critical nucleus size and the Zeldovich factor. Fitting with the Tolman's equation to the MD simulations yields the surface energy of a planar interface (∼0.9 J m{sup −2}) and the Tolman length (0.4–0.5 Å), and those values are in accord with those from integrating the stress profiles of a planar interface. Independent CNT predictions of the nucleation rate (10{sup 33−34} s{sup −1} m{sup −3}) and critical size (3–4 Å in radius) are in agreement with the MFPT and SP results. The JMA law can reasonably describe the nucleation and growth process. The size distribution of subcritical nuclei appears to follow a power law with an exponent decreasing with increasing tension owing to coupled nucleation and growth, and that of the supercritical nuclei becomes flattened during further stress relaxation due to void coalescence.« less

  12. Studies of cavitation and ice nucleation in 'doubly-metastable' water: time-lapse photography and neutron diffraction.

    PubMed

    Barrow, Matthew S; Williams, P Rhodri; Chan, Hoi-Houng; Dore, John C; Bellissent-Funel, Marie-Claire

    2012-10-14

    High-speed photographic studies and neutron diffraction measurements have been made of water under tension in a Berthelot tube. Liquid water was cooled below the normal ice-nucleation temperature and was in a doubly-metastable state prior to a collapse of the liquid state. This transition was accompanied by an exothermic heat release corresponding with the rapid production of a solid phase nucleated by cavitation. Photographic techniques have been used to observe the phase transition over short time scales in which a solidification front is observed to propagate through the sample. Significantly, other images at a shorter time interval reveal the prior formation of cavitation bubbles at the beginning of the process. The ice-nucleation process is explained in terms of a mechanism involving hydrodynamically-induced changes in tension in supercooled water in the near vicinity of an expanding cavitation bubble. Previous explanations have attributed the nucleation of the solid phase to the production of high positive pressures. Corresponding results are presented which show the initial neutron diffraction pattern after ice-nucleation. The observed pattern does not exhibit the usual crystalline pattern of hexagonal ice [I(h)] that is formed under ambient conditions, but indicates the presence of other ice forms. The composite features can be attributed to a mixture of amorphous ice, ice-I(h)/I(c) and the high-pressure form, ice-III, and the diffraction pattern continues to evolve over a time period of about an hour.

  13. Effects of ultrasound-induced inertial cavitation on enzymatic thrombolysis.

    PubMed

    Chuang, Yueh-Hsun; Cheng, Po-Wen; Chen, Szu-Chia; Ruan, Jia-Ling; Li, Pai-Chi

    2010-04-01

    Cavitation induced by ultrasound enhances enzymatic fibrinolysis by increasing the transport of reactants. However, the effects of cavitation need to be fully understood before sonothrombolysis can be applied clinically. In order to understand the underlying mechanisms, we examined the effects of combining ultrasound, microbubbles and thrombolytic enzymes on thrombolysis. First, we evaluated the relations between inertial cavitation and the reduction in the weight of a blood clot. Inertial cavitation was varied by changing the amplitude and duration of the transmitted acoustic wave as well as the concentration of microbubbles used to induce cavitation. Second, we studied the combined effects of streptokinase and inertial cavitation on thrombolysis. The results show that inertial cavitation increases the weight reduction of a blood clot by up to 33.9%. With linear regression fitting, the measured differential inertial cavitation dose and the weight reduction had a correlation coefficient of 0.66. Microscopically, enzymatic thrombolysis effects manifest as multiple large cavities within the clot that are uniformly distributed on the side exposed to ultrasound. This suggests that inertial cavitation plays an important role in producing cavities, while microjetting of the microbubbles induces pits on the clot surface. These observations preliminarily demonstrate the clinical potential of sonothrombolysis. The use of the differential inertial cavitation dose as an indicator of blood clot weight loss for controlled sonothrombolysis is also possible and will be further explored.

  14. Transition of cavitating flow to supercavitation within Venturi nozzle - hysteresis investigation

    NASA Astrophysics Data System (ADS)

    Jiří, Kozák; Pavel, Rudolf; Rostislav, Huzlík; Martin, Hudec; Radomír, Chovanec; Ondřej, Urban; Blahoslav, Maršálek; Eliška, Maršálková; František, Pochylý; David, Štefan

    Cavitation is usually considered as undesirable phenomena. On the other hand, it can be utilized in many applications. One of the technical applications is using cavitation in water treatment, where hydrodynamic cavitation seems to be effective way how to reduce cyanobacteria within large bulks of water. The main scope of this paper is investigation of the cavitation within Venturi nozzle during the transition from fully developed cavitation to supercavitation regime and vice versa. Dynamics of cavitation was investigated using experimental data of pressure pulsations and analysis of high speed videos, where FFT of the pixel intensity and Proper Orthogonal Decomposition (POD) of the records were done to identify dominant frequencies connected with the presence of cavitation. The methodology of the high speed (HS) records semiautomated analysis using the FFT was described. Obtained results were correlated and above that the possible presence of hysteresis was discussed.

  15. Ultrafast cavitation induced by an X-ray laser in water drops

    NASA Astrophysics Data System (ADS)

    Stan, Claudiu; Willmott, Philip; Stone, Howard; Koglin, Jason; Liang, Mengning; Aquila, Andrew; Robinson, Joseph; Gumerlock, Karl; Blaj, Gabriel; Sierra, Raymond; Boutet, Sebastien; Guillet, Serge; Curtis, Robin; Vetter, Sharon; Loos, Henrik; Turner, James; Decker, Franz-Josef

    2016-11-01

    Cavitation in pure water is determined by an intrinsic heterogeneous cavitation mechanism, which prevents in general the experimental generation of large tensions (negative pressures) in bulk liquid water. We developed an ultrafast decompression technique, based on the reflection of shock waves generated by an X-ray laser inside liquid drops, to stretch liquids to large negative pressures in a few nanoseconds. Using this method, we observed cavitation in liquid water at pressures below -100 MPa. These large tensions exceed significantly those achieved previously, mainly due to the ultrafast decompression. The decompression induced by shock waves generated by an X-ray laser is rapid enough to continue to stretch the liquid phase after the heterogeneous cavitation occurs in water, despite the rapid growth of cavitation nanobubbles. We developed a nucleation-and-growth hydrodynamic cavitation model that explains our results and estimates the concentration of heterogeneous cavitation nuclei in water.

  16. Kaplan turbine tip vortex cavitation - analysis and prevention

    NASA Astrophysics Data System (ADS)

    Motycak, L.; Skotak, A.; Kupcik, R.

    2012-11-01

    The work is focused on one type of Kaplan turbine runner cavitation - a tip vortex cavitation. For detailed description of the tip vortex, the CFD analysis is used. On the basis of this analysis it is possible to estimate the intensity of cavitating vortex core, danger of possible blade surface and runner chamber cavitation pitting. In the paper, the ways how to avoid the pitting effect of the tip vortex are described. In order to prevent the blade surface against pitting, the following possibilities as the change of geometry of the runner blade, dimension of tip clearance and finally the installation of the anti-cavitation lips are discussed. The knowledge of the shape and intensity of the tip vortex helps to design the anti-cavitation lips more sophistically. After all, the results of the model tests of the Kaplan runner with or without anti-cavitation lips and the results of the CFD analysis are compared.

  17. Laser-nucleated acoustic cavitation in focused ultrasound.

    PubMed

    Gerold, Bjoern; Kotopoulis, Spiros; McDougall, Craig; McGloin, David; Postema, Michiel; Prentice, Paul

    2011-04-01

    Acoustic cavitation can occur in therapeutic applications of high-amplitude focused ultrasound. Studying acoustic cavitation has been challenging, because the onset of nucleation is unpredictable. We hypothesized that acoustic cavitation can be forced to occur at a specific location using a laser to nucleate a microcavity in a pre-established ultrasound field. In this paper we describe a scientific instrument that is dedicated to this outcome, combining a focused ultrasound transducer with a pulsed laser. We present high-speed photographic observations of laser-induced cavitation and laser-nucleated acoustic cavitation, at frame rates of 0.5×10(6) frames per second, from laser pulses of energy above and below the optical breakdown threshold, respectively. Acoustic recordings demonstrated inertial cavitation can be controllably introduced to the ultrasound focus. This technique will contribute to the understanding of cavitation evolution in focused ultrasound including for potential therapeutic applications. © 2011 American Institute of Physics

  18. Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low-frequency sonophoresis.

    PubMed

    Tezel, Ahmet; Mitragotri, Samir

    2003-12-01

    Interactions of acoustic cavitation bubbles with biological tissues play an important role in biomedical applications of ultrasound. Acoustic cavitation plays a particularly important role in enhancing transdermal transport of macromolecules, thereby offering a noninvasive mode of drug delivery (sonophoresis). Ultrasound-enhanced transdermal transport is mediated by inertial cavitation, where collapses of cavitation bubbles microscopically disrupt the lipid bilayers of the stratum corneum. In this study, we describe a theoretical analysis of the interactions of cavitation bubbles with the stratum corneum lipid bilayers. Three modes of bubble-stratum corneum interactions including shock wave emission, microjet penetration into the stratum corneum, and impact of microjet on the stratum corneum are considered. By relating the mechanical effects of these events on the stratum corneum structure, the relationship between the number of cavitation events and collapse pressures with experimentally measured increase in skin permeability was established. Theoretical predictions were compared to experimentally measured parameters of cavitation events.

  19. Probability of cavitation for single ultrasound pulses applied to tissues and tissue-mimicking materials.

    PubMed

    Maxwell, Adam D; Cain, Charles A; Hall, Timothy L; Fowlkes, J Brian; Xu, Zhen

    2013-03-01

    In this study, the negative pressure values at which inertial cavitation consistently occurs in response to a single, two-cycle, focused ultrasound pulse were measured in several media relevant to cavitation-based ultrasound therapy. The pulse was focused into a chamber containing one of the media, which included liquids, tissue-mimicking materials, and ex vivo canine tissue. Focal waveforms were measured by two separate techniques using a fiber-optic hydrophone. Inertial cavitation was identified by high-speed photography in optically transparent media and an acoustic passive cavitation detector. The probability of cavitation (P(cav)) for a single pulse as a function of peak negative pressure (p(-)) followed a sigmoid curve, with the probability approaching one when the pressure amplitude was sufficient. The statistical threshold (defined as P(cav) = 0.5) was between p(-) = 26 and 30 MPa in all samples with high water content but varied between p(-) = 13.7 and >36 MPa in other media. A model for radial cavitation bubble dynamics was employed to evaluate the behavior of cavitation nuclei at these pressure levels. A single bubble nucleus with an inertial cavitation threshold of p(-) = 28.2 megapascals was estimated to have a 2.5 nm radius in distilled water. These data may be valuable for cavitation-based ultrasound therapy to predict the likelihood of cavitation at various pressure levels and dimensions of cavitation-induced lesions in tissue. Copyright © 2013 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  20. Sub-scale Waterflow Cavitation and Dynamic Transfer Function Testing of an Oxidizer Turbo-Pump Combined Inducer and Impeller

    NASA Technical Reports Server (NTRS)

    Karon, D. M.; Patel, S. K.; Zoladz, T. F.

    2016-01-01

    In 2009 and 2010, Concepts NREC prepared for and performed a series of tests on a 52% scale of a version of the Pratt & Whitney Rocketdyne J-2X Oxidizer Turbopump under a Phase III SBIR with NASA MSFC. The test article was a combined inducer and impeller, tested as a unit. This paper presents an overview of the test rig and facility, instrumentation, signal conditioning, data acquisition systems, testing approach, measurement developments, and lessons learned. Results from these tests were presented in the form of two papers at the previous JANNAF joint propulsion conference, in December of 2011.

  1. Limitations of the Weissler reaction as a model reaction for measuring the efficiency of hydrodynamic cavitation.

    PubMed

    Morison, K R; Hutchinson, C A

    2009-01-01

    The Weissler reaction in which iodide is oxidised to a tri-iodide complex (I(3)(-)) has been widely used for measurement of the intensity of ultrasonic and hydrodynamic cavitation. It was used in this work to compare ultrasonic cavitation at 24 kHz with hydrodynamic cavitation using two different devices, one a venturi and the other a sudden expansion, operated up to 8.7 bar. Hydrodynamic cavitation had a maximum efficiency of about 5 x 10(-11) moles of I(3)(-) per joule of energy compared with the maximum of almost 8 x 10(-11) mol J(-1) for ultrasonic cavitation. Hydrodynamic cavitation was found to be most effective at 10 degrees C compared with 20 degrees C and 30 degrees C and at higher upstream pressures. However, it was found that in hydrodynamic conditions, even without cavitation, I(3)(-) was consumed at a rapid rate leading to an equilibrium concentration. It was concluded that the Weissler reaction was not a good model reaction for the assessment of the effectiveness of hydrodynamic cavitation.

  2. The issue of cavitation number value in studies of water treatment by hydrodynamic cavitation.

    PubMed

    Šarc, Andrej; Stepišnik-Perdih, Tadej; Petkovšek, Martin; Dular, Matevž

    2017-01-01

    Within the last years there has been a substantial increase in reports of utilization of hydrodynamic cavitation in various applications. It has came to our attention that many times the results are poorly repeatable with the main reason being that the researchers put significant emphasis on the value of the cavitation number when describing the conditions at which their device operates. In the present paper we firstly point to the fact that the cavitation number cannot be used as a single parameter that gives the cavitation condition and that large inconsistencies in the reports exist. Then we show experiments where the influences of the geometry, the flow velocity, the medium temperature and quality on the size, dynamics and aggressiveness of cavitation were assessed. Finally we show that there are significant inconsistencies in the definition of the cavitation number itself. In conclusions we propose a number of parameters, which should accompany any report on the utilization of hydrodynamic cavitation, to make it repeatable and to enable faster progress of science and technology development. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Killing rate of colony count by hydrodynamic cavitation due to square multi-orifice plates

    NASA Astrophysics Data System (ADS)

    Dong, Zhiyong; Zhao, Wenqian

    2018-02-01

    Currently,in water supply engineering, the conventional technique of disinfection by chlorination is employed to kill pathogenic microorganisms in raw water. However, chlorine reacts with organic compounds in water and generates disinfection byproducts (DBPs), such as trihalomethanes (THMs), haloacetic acids (HAAs) etc. These byproducts are of carcinogenic, teratogenic and mutagenic effects, which seriously threaten human health. Hydrodynamic cavitation is a novel technique of drinking water disinfection without DBPs. Effects of orifice size, orifice number and orifice layout of multi-orifice plate, cavitation number, cavitation time and orifice velocity on killing pathogenic microorganisms by cavitation were investigated experimentally in a self-developed square multi-orifice plate-type hydrodynamic cavitation device. The experimental results showed that cavitation effects increased with decrease in orifice size and increase in orifice number, cavitation time and orifice velocity. Along with lowering in cavitation number, there was an increase in Reynolds shear stress,thus enhancing the killing rate of pathogenic microorganism in raw water. In addition, the killing rate by staggered orifice layout was greater than that by checkerboard-type orifice layout.

  4. Long-time cavitation threshold of silica water mixture under acoustic drive

    NASA Astrophysics Data System (ADS)

    Bussonniére, Adrien; Liu, Qingxia; Tsai, Peichun Amy

    2017-11-01

    The low cavitation threshold of water observed experimentally has been attributed to the presence of pre-existing tiny bubbles stabilized by impurities. However, the origin and stability of these cavitation nuclei remain unresolved. We therefore investigate the long-time cavitation evolution of water seeded with micron-sized silica particles under the influences of several parameters. Experimentally, cavitation is induced by a High Intensity Focused Ultrasound and subsequently detected by monitoring the backscattered sound. Degassed or aerated solutions of different concentrations are subjected to acoustic pulses (with the amplitude ranging from 0.1 to 1.7 MPa and a fixed repetition frequency between 0.1 and 6.5 Hz). The cavitation threshold was measured by fitting the cavitation probability curve, averaged over 1000 pulses. Surprisingly, our results shown that the cavitation threshold stabilizes at a reproducible value after a few thousand pulses. Moreover, this long-time threshold was found to decrease with increasing particle concentration, pulse period, and initial oxygen level. In contrast to the depletion of nuclei expected under long acoustic cavitation, the results suggest stabilized nuclei population depending on concentration, oxygen level, and driving period.

  5. Using acoustic cavitation to enhance chemotherapy of DOX liposomes: experiment in vitro and in vivo.

    PubMed

    Zhao, Ying-Zheng; Dai, Dan-Dan; Lu, Cui-Tao; Lv, Hai-Feng; Zhang, Yan; Li, Xing; Li, Wen-Feng; Wu, Yan; Jiang, Lei; Li, Xiao-Kun; Huang, Pin-Tong; Chen, Li-Juan; Lin, Min

    2012-09-01

    Experiments in vitro and in vivo were designed to investigate tumor growth inhibition of chemotherapeutics-loaded liposomes enhanced by acoustic cavitation. Doxorubicin-loaded liposomes (DOX liposomes) were used in experiments to investigate acoustic cavitation mediated effects on cell viability and chemotherapeutic function. The influence of lingering sensitive period after acoustic cavitation on tumor inhibition was also investigated. Animal experiment was carried out to verify the practicability of this technique in vivo. From experiment results, blank phospholipid-based microbubbles (PBM) combined with ultrasound (US) at intensity below 0.3 W/cm² could produce acoustic cavitation which maintained cell viability at high level. Compared with DOX solution, DOX liposomes combined with acoustic cavitation exerted effective tumor inhibition in vitro and in vivo. The lingering sensitive period after acoustic cavitation could also enhance the susceptibility of tumor to chemotherapeutic drugs. DOX liposomes could also exert certain tumor inhibition under preliminary acoustic cavitation. Acoustic cavitation could enhance the absorption efficiency of DOX liposomes, which could be used to reduce DOX adverse effect on normal organs in clinical chemotherapy.

  6. The effect of hydrodynamic cavitation on Microcystis aeruginosa: Physical and chemical factors.

    PubMed

    Li, Pan; Song, Yuan; Yu, Shuili; Park, Hee-Deung

    2015-10-01

    The various effects of hydrodynamic cavitation (HC) on algal growth inhibition were investigated. The gas-vacuolate species Microcystis aeruginosa responded differently to the gas-vacuole-negative alga Chlorella sp. When M. aeruginosa was subjected to HC, both its cell density and photosynthetic activity were subsequently reduced by nearly 90% after three days culture. However, the cell density of Chlorella sp. was reduced by only 63%, and its final photosynthetic activity was unaffected. Electron microscopy confirmed that HC had a minimal impact on algal cells that lack gas vacuoles. Shear stress during recirculation only modestly inhibited the growth of M. aeruginosa. The relative malondialdehyde (MDA) content, a quantitative indicator of lipid peroxidation, increased significantly during HC treatment, indicating the production of free radicals. Accordingly, the addition of H2O2 to the HC process promoted the production of free radicals, which also improved algal reduction. A comparison of the outcomes and energy efficiency of HC and ultrasonic cavitation indicated that HC gives the best performance: under 10 min cavitation treatment, the algal removal rate of HC could reach 88% while that of sonication was only 39%. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Cell damage evaluation of mammalian cells in cell manipulation by amplified femtosecond ytterbium laser

    NASA Astrophysics Data System (ADS)

    Hong, Z.-Y.; Iino, T.; Hagihara, H.; Maeno, T.; Okano, K.; Yasukuni, R.; Hosokawa, Y.

    2018-03-01

    A micrometer-scale explosion with cavitation bubble generation is induced by focusing a femtosecond laser in an aqueous solution. We have proposed to apply the explosion as an impulsive force to manipulate mammalian cells especially in microfluidic chip. Herein, we employed an amplified femtosecond ytterbium laser as an excitation source for the explosion and evaluated cell damage in the manipulation process to clarify the application potential. The damage of C2C12 myoblast cell prepared as a representative mammalian cell was investigated as a function of distance between cell and laser focal point. Although the cell received strong damage on the direct laser irradiation condition, the damage sharply decreased with increasing distance. Since the threshold distance, above which the cell had no damage, was consistent with radius of the cavitation bubble, impact of the cavitation bubble would be a critical factor for the cell damage. The damage had strong nonlinearity in the pulse energy dependence. On the other hand, cell position shift by the impact of the cavitation bubble was almost proportional to the pulse energy. In balance between the cell viability and the cell position shift, we elucidated controllability of the cell manipulation in microfluidic chip.

  8. Observation of pressure variation in the cavitation region of submerged journal bearings

    NASA Technical Reports Server (NTRS)

    Etsion, I.; Ludwig, L. P.

    1980-01-01

    Visual observations and pressure measurements in the cavitation zone of a submerged journal bearing are described. Tests were performed at various shaft speeds and ambient pressure levels. Some photographs of the cavitation region are presented showing strong reverse flow at the downstream end of the region. Pressure profiles are presented showing significant pressure variations inside the cavitation zone, contrary to common assumptions of constant cavitation pressure.

  9. Prediction of pump cavitation performance

    NASA Technical Reports Server (NTRS)

    Moore, R. D.

    1974-01-01

    A method for predicting pump cavitation performance with various liquids, liquid temperatures, and rotative speeds is presented. Use of the method requires that two sets of test data be available for the pump of interest. Good agreement between predicted and experimental results of cavitation performance was obtained for several pumps operated in liquids which exhibit a wide range of properties. Two cavitation parameters which qualitatively evaluate pump cavitation performance are also presented.

  10. Impact of L/D on 90 Degree Sharp-Edge Orifice Flow with Manifold Passage Cross Flow (Preprint)

    DTIC Science & Technology

    2007-04-30

    that are observed by measurement as the flow transitions from non-cavitation to cavitation (turbulent flow), supercavitation , and finally separation in...include inception of cavitation, supercavitation , and separation. 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF...cavitation to cavitation (turbulent flow), supercavitation , and finally separation in sharp-edge 90 degree orifices. This study includes orifice L/D from

  11. Detecting Cavitation Pitting Without Disassembly

    NASA Technical Reports Server (NTRS)

    Barkhoudarian, S.

    1986-01-01

    Technique for detecting cavitation pitting in pumps, turbines, and other machinery uses low-level nuclear irradiation. Isotopes concentrated below surface emit gamma radiation, a portion of which is attenuated by overlying material. Where there are cavitation pits, output of gamma-ray detector fluctuates as detector is scanned near pits. Important to detect cavitation pits because nozzle, turbine blade, or other pump component weakened by cavitation could fail catastrophically and cause machine to explode.

  12. Observations on Rotating Cavitation and Cavitation Surge from the Development of the Fastrac Engine Turbopump

    NASA Technical Reports Server (NTRS)

    Zoladz, Thomas F.

    2000-01-01

    Observations regarding rotating cavitation and cavitation surge experienced during the development of the Fastrac engine turbopump are discussed. Detailed observations acquired from the analysis of both water flow and liquid oxygen test data are offered in this paper. Scaling and general comparison of rotating cavitation between water flow and liquid oxygen testing are discussed. Complex data features linking the localized rotating cavitation mechanism of the inducer to system surge components are described in detail. Finally a description of a lumped-parameter hydraulic system model developed to better understand observed data is given.

  13. Overview of Rotating Cavitation and Cavitation Surge in the Fastrac Engine LOX Turbopump

    NASA Technical Reports Server (NTRS)

    Zoladz, Thomas; Turner, Jim (Technical Monitor)

    2001-01-01

    Observations regarding rotating cavitation and cavitation surge experienced during the development of the Fastrac 60 Klbf engine turbopump are discussed. Detailed observations from the analysis of both water flow and liquid oxygen test data are offered. Scaling and general comparison of rotating cavitation between water flow and liquid oxygen testing are discussed. Complex data features linking the localized rotating cavitation mechanism of the inducer to system surge components are described in detail. Finally a description of a simple lumped-parameter hydraulic system model developed to better understand observed data is given.

  14. Experimental investigation of hydrodynamic cavitation through orifices of different geometries

    NASA Astrophysics Data System (ADS)

    Rudolf, Pavel; Kubina, Dávid; Hudec, Martin; Kozák, Jiří; Maršálek, Blahoslav; Maršálková, Eliška; Pochylý, František

    Hydrodynamic cavitation in single and multihole orifices was experimentally investigated to assess their hydraulic characteristics: loss coefficients, inception cavitation number, cavitation number for transition to supercavitation. Significant difference for singlehole and multihole orifices was observed in terms of the measured loss coefficient. It is significantly more effective to use multihole orifices, where energy dissipation is much lower.It was found that using scaling factor given by ratio of orifice thickness suggests linear behaviour of both loss coefficient and inception cavitation number. Orifices seem to be convenient choice as flow constriction devices inducing cavitation due to their simplicity.

  15. Bubbly cavitating flow generation and investigation of its erosional nature for biomedical applications.

    PubMed

    Koşar, Ali; Şeşen, Muhsincan; Oral, Ozlem; Itah, Zeynep; Gozuacik, Devrim

    2011-05-01

    This paper presents a study that investigates the destructive energy output resulting from hydrodynamic bubbly cavitation in microchannels and its potential use in biomedical applications. The research performed in this study includes results from bubbly cavitation experiments and findings showing the destructive effects of bubbly cavitating flow on selected solid specimens and live cells. The bubbles generated by hydrodynamic cavitation are highly destructive at the surfaces of the target medium on which they are carefully focused. The resulting destructive energy output could be effectively used for biomedical treatments, such as destroying kidney stones (renal calculi) or killing cancer cells. Motivated by this potential, the cavitation damage to cancerous cells and material removal from chalk pieces (which possess similar material properties as some kidney stones) was investigated. Our results showed that cavitation could induce damage both on chalk pieces and leukemia/lymphoma cells. We discovered that hydrodynamic cavitation exposure had early and delayed effects on cancer cell survival. Hence, the potential of hydrodynamic bubbly cavitation generated at the microscale for biomedical treatments was revealed using the microchannel configuration as a microorifice (with an inner diameter of 147 μm and a length of 1.52 cm), which acts as the source of bubbly cavitating flows. © 2011 IEEE

  16. Experimental Investigation of Cavitation Induced Feedline Instability from an Orifice

    NASA Technical Reports Server (NTRS)

    Hitt, Matthew A.; Lineberry, David M.; Ahuja, Vineet; Frederick, Robert A,

    2012-01-01

    This paper details the results of an experimental investigation into the cavitation instabilities created by a circular orifice conducted at the University of Alabama in Huntsville Propulsion Research Center. This experiment was conducted in concert with a computational simulation to serve as a reference point for the simulation. Testing was conducted using liquid nitrogen as a cryogenic propellant simulant. A 1.06 cm diameter thin orifice with a rounded inlet was tested in an approximately 1.25 kg/s flow with inlet pressures ranging from 504.1 kPa to 829.3 kPa. Pressure fluctuations generated by the orifice were measured using a high frequency pressure sensor located 0.64 tube diameters downstream of the orifice. Fast Fourier Transforms were performed on the high frequency data to determine the instability frequency. Shedding resulted in a primary frequency with a cavitation related subharmonic frequency. For this experiment, the cavitation instability ranged from 153 Hz to 275 Hz. Additionally, the strength of the cavitation occur red as a function of cavitation number. At lower cavitation numbers, the strength of the cavitation instability ranged from 2.4 % to 7 % of the inlet pressure. However, at higher cavitation numbers, the strength of the cavitation instability ranged from 0.6 % to 1 % of the inlet pressure.

  17. Propeller sheet cavitation noise source modeling and inversion

    NASA Astrophysics Data System (ADS)

    Lee, Keunhwa; Lee, Jaehyuk; Kim, Dongho; Kim, Kyungseop; Seong, Woojae

    2014-02-01

    Propeller sheet cavitation is the main contributor to high level of noise and vibration in the after body of a ship. Full measurement of the cavitation-induced hull pressure over the entire surface of the affected area is desired but not practical. Therefore, using a few measurements on the outer hull above the propeller in a cavitation tunnel, empirical or semi-empirical techniques based on physical model have been used to predict the hull-induced pressure (or hull-induced force). In this paper, with the analytic source model for sheet cavitation, a multi-parameter inversion scheme to find the positions of noise sources and their strengths is suggested. The inversion is posed as a nonlinear optimization problem, which is solved by the optimization algorithm based on the adaptive simplex simulated annealing algorithm. Then, the resulting hull pressure can be modeled with boundary element method from the inverted cavitation noise sources. The suggested approach is applied to the hull pressure data measured in a cavitation tunnel of the Samsung Heavy Industry. Two monopole sources are adequate to model the propeller sheet cavitation noise. The inverted source information is reasonable with the cavitation dynamics of the propeller and the modeled hull pressure shows good agreement with cavitation tunnel experimental data.

  18. Effects of Radio Frequency and Ultrasound Cavitation Therapy on Serum C-reactive Protein and Pro-oxidant-Antioxidant Levels.

    PubMed

    Mohammadzadeh, Mahsa; Nasrfard, Samira; Nezafati, Pouya; Arabpour, Mahla; Ghaane, Narjes; Salehi, Maryam; Safarian, Mohammad; Ghayour-Mobarhan, Majid; Ferns, Gordon A; Norouzy, Abdolreza

    2016-05-01

    A combination of radio-frequency (RF) and ultrasound cavitation (UC) has been reported to reduce indices of obesity. In this study, we aimed to investigate the effect of a combination of these techniques on anthropometric indices, pro-oxidant-antioxidant balance (PAB), and serum high-sensitivity C-reactive protein (hs-CRP). This randomized clinical trial was performed on 50 healthy women between January 2014 and June 2014 in Ghaem Hospital, Mashhad, Iran. Participants were randomized to one of two groups, both of which received a low-calorie diet containing 500-kcal energy deficit per day. The trial group included twenty-five subjects who were assigned to the combined treatment of RF and ultrasound cavitation program of abdomen and flank areas. There were twenty-five control subjects who received the low calorie diet alone. Biochemical markers, including serum hs-CRP and PAB values, and anthropometric indices were measured in the intervention group and healthy controls. For both the intervention and control groups, waist circumference was reduced significantly by 3.76 ± 1.69 and 2.40 ± 1.04, respectively (P < 0.05). In addition, abdominal circumference was reduced by 9.5 ± 2.66 and 3.12 ± 1.88, in these groups, respectively (P < 0.001). Decrement of PAB level in the intervention group, and its increment in the control group, were not significant (P > 0.05). In addition, reductions of hs-CRP and PAB between the two studied groups during five weeks of study were not significant (P > 0.05). Although there were significant reductions in anthropometric indices following treatment with RF and UC, the effects on serum PAB or hs-CRP were no significantly different, compared to the control group. Further studies are needed to confirm the beneficial effect for the use of these techniques.

  19. Influence of shock wave pressure amplitude and pulse repetition frequency on the lifespan, size and number of transient cavities in the field of an electromagnetic lithotripter.

    PubMed

    Huber, P; Jöchle, K; Debus, J

    1998-10-01

    Monitoring the generation of cavitation is of great interest for diagnostic and therapeutic use of ultrasound in medicine, since cavitation is considered to play a major role in nonthermal ultrasound interactions with tissue. Important parameters are the number of cavitation events and the energy released during the bubble collapse. This energy is correlated to the maximum bubble radius which is related to the cavitation lifespan. The aim of this study was therefore to investigate the influence of the acoustic pressure amplitude and the pulse repetition frequency (PRF) in the field of a lithotripter (Lithostar, Siemens) on the number, size and lifespan of transient cavitation bubbles in water. We used scattered laser light recorded by a photodiode and stroboscopic photographs to monitor the cavitation activity. We found that PRF (range 0.5-5 Hz) had no influence on the cavitation bubble lifespan and size, whereas lifespan and size increased with the acoustic pressure amplitude. In contrast, the number of cavitation events strongly increased with PRF, whereas the pressure amplitude had no significant influence on the number of cavitation events. Thus, by varying the pressure amplitude and PRF, it might be possible to deliver a defined relative number of cavitations at a defined relative energy level in a defined volume. This seems to be relevant to further studies that address the biological effects of transient cavitation occurring in the fields of lithotripters.

  20. Towards the concept of hydrodynamic cavitation control

    NASA Astrophysics Data System (ADS)

    Chatterjee, Dhiman; Arakeri, Vijay H.

    1997-02-01

    A careful study of the existing literature available in the field of cavitation reveals the potential of ultrasonics as a tool for controlling and, if possible, eliminating certain types of hydrodynamic cavitation through the manipulation of nuclei size present in a flow. A glass venturi is taken to be an ideal device to study the cavitation phenomenon at its throat and its potential control. A piezoelectric transducer, driven at the crystal resonant frequency, is used to generate an acoustic pressure field and is termed an ‘ultrasonic nuclei manipulator (UNM)’. Electrolysis bubbles serve as artificial nuclei to produce travelling bubble cavitation at the venturi throat in the absence of a UNM but this cavitation is completely eliminated when a UNM is operative. This is made possible because the nuclei, which pass through the acoustic field first, cavitate, collapse violently and perhaps fragment and go into dissolution before reaching the venturi throat. Thus, the potential nuclei for travelling bubble cavitation at the venturi throat seem to be systematically destroyed through acoustic cavitation near the UNM. From the solution to the bubble dynamics equation, it has been shown that the potential energy of a bubble at its maximum radius due to an acoustic field is negligible compared to that for the hydrodynamic field. Hence, even though the control of hydrodynamic macro cavitation achieved in this way is at the expense of acoustic micro cavitation, it can still be considered to be a significant gain. These are some of the first results in this direction.

  1. On viscoelastic cavitating flows: A numerical study

    NASA Astrophysics Data System (ADS)

    Naseri, Homa; Koukouvinis, Phoevos; Malgarinos, Ilias; Gavaises, Manolis

    2018-03-01

    The effect of viscoelasticity on turbulent cavitating flow inside a nozzle is simulated for Phan-Thien-Tanner (PTT) fluids. Two different flow configurations are used to show the effect of viscoelasticity on different cavitation mechanisms, namely, cloud cavitation inside a step nozzle and string cavitation in an injector nozzle. In incipient cavitation condition in the step nozzle, small-scale flow features including cavitating microvortices in the shear layer are suppressed by viscoelasticity. Flow turbulence and mixing are weaker compared to the Newtonian fluid, resulting in suppression of microcavities shedding from the cavitation cloud. Moreover, mass flow rate fluctuations and cavity shedding frequency are reduced by the stabilizing effect of viscoelasticity. Time averaged values of the liquid volume fraction show that cavitation formation is strongly suppressed in the PTT viscoelastic fluid, and the cavity cloud is pushed away from the nozzle wall. In the injector nozzle, a developed cloud cavity covers the nozzle top surface, while a vortex-induced string cavity emerges from the turbulent flow inside the sac volume. Similar to the step nozzle case, viscoelasticity reduces the vapor volume fraction in the cloud region. However, formation of the streamwise string cavity is stimulated as turbulence is suppressed inside the sac volume and the nozzle orifice. Vortical perturbations in the vicinity of the vortex are damped, allowing more vapor to develop in the string cavity region. The results indicate that the effect of viscoelasticity on cavitation depends on the alignment of the cavitating vortices with respect to the main flow direction.

  2. Degradation of alachlor in aqueous solution by using hydrodynamic cavitation.

    PubMed

    Wang, Xikui; Zhang, Yong

    2009-01-15

    The degradation of alachlor aqueous solution by using hydrodynamic cavitation was systematically investigated. It was found that alachlor in aqueous solution can be deomposed with swirling jet-induced cavitation. The degradation can be described by a pseudo-first-order kinetics and the degradation rate was found to be 4.90x10(-2)min(-1). The effects of operating parameters such as fluid pressure, solution temperature, initial concentration of alachlor and medium pH on the degradation rates of alachlor were also discussed. The results showed that the degradation rates of alachlor increased with increasing pressure and decreased with increasing initial concentration. An optimum temperature of 40 degrees C existed for the degradation rate of alachlor and the degradation rate was also found to be slightly depend on medium pH. Many degradation products formed during the process, and some of them were qualitatively identified by GC-MS.

  3. An Acoustofluidic Micromixer via Bubble Inception and Cavitation from Microchannel Sidewalls

    PubMed Central

    2015-01-01

    During the deep reactive ion etching process, the sidewalls of a silicon mold feature rough wavy structures, which can be transferred onto a polydimethylsiloxane (PDMS) microchannel through the soft lithography technique. In this article, we utilized the wavy structures of PDMS microchannel sidewalls to initiate and cavitate bubbles in the presence of acoustic waves. Through bubble cavitation, this acoustofluidic approach demonstrates fast, effective mixing in microfluidics. We characterized its performance by using viscous fluids such as poly(ethylene glycol) (PEG). When two PEG solutions with a resultant viscosity 54.9 times higher than that of water were used, the mixing efficiency was found to be 0.92, indicating excellent, homogeneous mixing. The acoustofluidic micromixer presented here has the advantages of simple fabrication, easy integration, and capability to mix high-viscosity fluids (Reynolds number: ∼0.01) in less than 100 ms. PMID:24754496

  4. MS2 and ΦX174 inactivation by high frequency ultrasound

    NASA Astrophysics Data System (ADS)

    Manariotis, I. D.; Syngouna, V.; Chrysikopoulos, C. V.

    2012-04-01

    Biocolloid inactivation in water with the use of ultrasound can be quite effective, because the implosion of cavitation bubbles can generate high temperatures and pressures at the heart of collapsed bubbles. Biocolloid inactivation by cavitation takes place due to a combination of simultaneously acting processes involving mechanical effects (caused by turbulence generation, microstreaming, liquid circulation currents, and shear stresses), chemical effects of cavitation (generation of active free radicals), and heat effects (generation of local hot spots). Generally, the mechanical effects are more responsible for biocolloid disinfection, whereas the chemical and heat effects play only a supporting role. The present study focuses on inactivation of MS2 and ΦΧ174 at three different relatively high frequencies (i.e. 582, 862, and 1142 kHz). The experimental results indicate that, for all three frequencies and power input of 133 W, both phages were at least 90% inactivated after 60 min of sonication.

  5. Effect of microbubble-induced cavitation on the dispersion of sprays

    NASA Astrophysics Data System (ADS)

    van der Voort, D. D.; Dam, N. J.; Kunnen, R. P. J.; van Heijst, G. J. F.; Clercx, H. J. H.

    2017-03-01

    The presence of bubbles and voids inside nozzles has a large effect on the morphology and atomization of sprays. In this investigation the voids formed by microbubbles entering the nozzle are investigated using transparent glass nozzles, pressure transducers, and high-speed diffuse backlight imaging. A correlation is found between the magnitude of pressure pulses inside the nozzle and the size of the bubbles causing these pulses. This relation allows the prediction of cavity formation also in nontransparent nozzles, which allow more realistic conditions of operation. Subsequently, the direct measurements of dispersion derived from the spread of glowing fluid showed no significant increase of the dispersion compared to cavitation-free conditions. This indicates that, while the spray angle may increase, the turbulence (in both liquid and gas phase) that governs the dispersion remains the same and the cavitation bubble events do not have a significant impact on this process.

  6. Thresholds of Transient Cavitation Produced by Pulsed Ultrasound in a Controlled Nuclei Environment.

    NASA Astrophysics Data System (ADS)

    Holland, Christy Katherine Smith

    The possibility of hazardous bioeffects from medical ultrasound examinations and therapy, although not demonstrated in current epidemiologic data, is still of interest to the medical community. In particular, concern persists over the potential of damage at the cellular level due to transient cavitation produced by diagnostic and high intensity therapeutic ultrasound. Transient cavitation is a discrete phenomenon which relies on the existence of stabilized nuclei, or pockets of gas within a host fluid, for its genesis. A convenient descriptor for assessing the likelihood of transient cavitation is the threshold pressure, or the minimum acoustic pressure necessary to initiate bubble growth and subsequent collapse. Experimental measurements of cavitation thresholds are presented here which elucidate the importance of ultrasound host fluid and nuclei parameters in determining these thresholds. These results are interpreted in the context of an approximate theory, included as an appendix, describing the relationship between these parameters and cavitation threshold pressures. An automated experimental apparatus has been developed to determine thresholds for cavitation produced in a fluid by short tone bursts of ultrasound at 0.76, 0.99, and 2.30 MHz. A fluid jet was used to convect potential cavitation nuclei through the focal region of the insonifying transducer. Potential nuclei tested include 1mum polystyrene spheres, microbubbles in the 1-10 μm range that are stabilized with human serum albumin, and whole blood constituents. Cavitation was detected by a passive acoustical technique which is sensitive to sound scattered from cavitation bubbles. Measurements of the transient cavitation threshold in water, in a fluid of higher viscosity, and in diluted whole blood are presented. Results from these experiments which permit the control of nuclei and host fluid properties are compared to the approximate analytical theory for the prediction of the onset of cavitation.

  7. Tumoral cavitation in patients with non-small-cell lung cancer treated with antiangiogenic therapy using bevacizumab

    PubMed Central

    Nishino, Mizuki; Cryer, Sarah K.; Okajima, Yuka; Sholl, Lynette M.; Hatabu, Hiroto; Rabin, Michael S.; Jackman, David M.; Johnson, Bruce E.

    2012-01-01

    Abstract Rationale and objectives: To investigate the frequency and radiographic patterns of tumoral cavitation in patients with non-small cell lung cancer (NSCLC) treated with bevacizumab, and correlate the imaging findings with the pathology, clinical characteristics and outcome. Materials and methods: Seventy-two patients with NSCLC treated with bevacizumab therapy were identified retrospectively. Baseline and follow-up chest computed tomography scan were reviewed to identify tumoral cavitation and subsequent filling in of cavitation. Radiographic cavitation patterns were classified into 3 groups. The clinical and outcome data were correlated with cavity formation and patterns. Results: Out of 72 patients, 14 patients developed cavitation after the initiation of bevacizumab therapy (19%; median time to event, 1.5 months; range 1.0–24.8 months). Three radiographic patterns of tumoral cavitation were noted: (1) development of cavity within the dominant lung tumor (n = 8); (2) development of non-dominant cavitary nodules (n = 3); and (3) development of non-dominant cavitary nodules with adjacent interstitial abnormalities (n = 3). Eleven patients (79%) demonstrated subsequent filling in of cavitation (the time from the cavity formation to filling in; median 3.7 months; range 1.9–22.7 months). No significant difference was observed in the clinical characteristics, including smoking history, or in the survival between patients who developed cavitation and those who did not. Smoking history demonstrated a significant difference across 3 radiographic cavitation patterns (P = 0.006). Hemoptysis was noted in 1 patient with cavity formation and 4 patients without, with no significant difference between the 2 groups. Conclusion: Tumoral cavitation occurred in 19% in patients with NSCLC treated with bevacizumab and demonstrated 3 radiographic patterns. Subsequent filling in of cavitation was noted in the majority of cases. PMID:22743083

  8. Flow Characteristics and Status of CFD Hydrodynamic Model Development in Sudden Contraction Manifold/Orifice Configurations

    DTIC Science & Technology

    2011-07-01

    Branching Configuration 33 6.6 CONTRACTION COEFFICIENT 35 7.0 SUPERCAVITATION 36 7.1 FLOW REATTACHMENT 36 7.1.1 In-Line... SUPERCAVITATION 37 7.2.1 In-Line Configuration Critical Cavitation 37 7.2.2 Dead Head Configuration Critical Cavitation 38 7.2.3 Approach...regimes are: (1) Non-Cavitation, (2) Inception of Cavitation, (3) Full Cavitation, (4) Supercavitation , and (5) Hydraulic Flip. The flow

  9. Regulating Ultrasound Cavitation in order to Induce Reproducible Sonoporation

    NASA Astrophysics Data System (ADS)

    Mestas, J.-L.; Alberti, L.; El Maalouf, J.; Béra, J.-C.; Gilles, B.

    2010-03-01

    Sonoporation would be linked to cavitation, which generally appears to be a non reproducible and unstationary phenomenon. In order to obtain an acceptable trade-off between cell mortality and transfection, a regulated cavitation generator based on an acoustical cavitation measurement was developed and tested. The medium to be sonicated is placed in a sample tray. This tray is immersed in in degassed water and positioned above the face of a flat ultrasonic transducer (frequency: 445 kHz; intensity range: 0.08-1.09 W/cm2). This technical configuration was admitted to be conducive to standing-wave generation through reflection at the air/medium interface in the well thus enhancing the cavitation phenomenon. Laterally to the transducer, a homemade hydrophone was oriented to receive the acoustical signal from the bubbles. From this spectral signal recorded at intervals of 5 ms, a cavitation index was calculated as the mean of the cavitation spectrum integration in a logarithmic scale, and the excitation power is automatically corrected. The device generates stable and reproducible cavitation level for a wide range of cavitation setpoint from stable cavitation condition up to full-developed inertial cavitation. For the ultrasound intensity range used, the time delay of the response is lower than 200 ms. The cavitation regulation device was evaluated in terms of chemical bubble collapse effect. Hydroxyl radical production was measured on terephthalic acid solutions. In open loop, the results present a great variability whatever the excitation power. On the contrary the closed loop allows a great reproducibility. This device was implemented for study of sonodynamic effect. The regulation provides more reproducible results independent of cell medium and experimental conditions (temperature, pressure). Other applications of this regulated cavitation device concern internalization of different particles (Quantum Dot) molecules (SiRNA) or plasmids (GFP, DsRed) into different types of cells (AT2, RL, LLC…). Preliminary results are presented.

  10. Influence of blade tip rounding on tip leakage vortex cavitation of axial flow pump

    NASA Astrophysics Data System (ADS)

    Wu, S. Q.; Shi, W. D.; Zhang, D. S.; Yao, J.; Cheng, C.

    2013-12-01

    Tip leakage flow in axial flow pumps is mainly caused by the tip clearance, which is the main cause of tip leakage vortex cavitation and blade tip cavitation erosion. In order to improve tip clearance flow and reduce TLV cavitation, four schemes were adopted to the round blade tip. These are: no tip rounding, one time tip clearance tip rounding, two times tip clearance tip rounding, four times tip clearance tip rounding. Using SST k-ω turbulence model and Zwart cavitation model in CFX software, this simulation obtained four kinds of inner flow field results. The numerical results indicated that with the increase of r*, NPSHc gradually increased and the cavitation performance reduced. However, corner vortex was eliminated so that cavitation in gap was restrained. But TLV vorticity increased and cavitation's range here had a little expansion. Combined with the research of this paper and the different analyses of four schemes, we recommend adopting the two times of the tip clearance rounding.

  11. Current Status in Cavitation Modeling

    NASA Technical Reports Server (NTRS)

    Singhal, Ashok K.; Avva, Ram K.

    1993-01-01

    Cavitation is a common problem for many engineering devices in which the main working fluid is in liquid state. In turbomachinery applications, cavitation generally occurs on the inlet side of pumps. The deleterious effects of cavitation include: lowered performance, load asymmetry, erosion and pitting of blade surfaces, vibration and noise, and reduction of the overall machine life. Cavitation models in use today range from rather crude approximations to sophisticated bubble dynamics models. Details about bubble inception, growth and collapse are relevant to the prediction of blade erosion, but are not necessary to predict the performance of pumps. An engineering model of cavitation is proposed to predict the extent of cavitation and performance. The vapor volume fraction is used as an indicator variable to quantify cavitation. A two-phase flow approach is employed with the assumption of the thermal equilibrium between liquid and vapor. At present velocity slip between the two phases is selected. Preliminary analyses of 2D flows shows qualitatively correct results.

  12. Interstitial Matrix Prevents Therapeutic Ultrasound From Causing Inertial Cavitation in Tumescent Subcutaneous Tissue.

    PubMed

    Koulakis, John P; Rouch, Joshua; Huynh, Nhan; Dubrovsky, Genia; Dunn, James C Y; Putterman, Seth

    2018-01-01

    We search for cavitation in tumescent subcutaneous tissue of a live pig under application of pulsed, 1-MHz ultrasound at 8 W cm -2 spatial peak and pulse-averaged intensity. We find no evidence of broadband acoustic emission indicative of inertial cavitation. These acoustic parameters are representative of those used in external-ultrasound-assisted lipoplasty and in physical therapy and our null result brings into question the role of cavitation in those applications. A comparison of broadband acoustic emission from a suspension of ultrasound contrast agent in bulk water with a suspension injected subcutaneously indicates that the interstitial matrix suppresses cavitation and provides an additional mechanism behind the apparent lack of in-vivo cavitation to supplement the absence of nuclei explanation offered in the literature. We also find a short-lived cavitation signal in normal, non-tumesced tissue that disappears after the first pulse, consistent with cavitation nuclei depletion in vivo. Copyright © 2018 World Federation for Ultrasound in Medicine and Biology. Published by Elsevier Inc. All rights reserved.

  13. Visualization of ultrasound induced cavitation bubbles using the synchrotron x-ray Analyzer Based Imaging technique.

    PubMed

    Izadifar, Zahra; Belev, George; Izadifar, Mohammad; Izadifar, Zohreh; Chapman, Dean

    2014-12-07

    Observing cavitation bubbles deep within tissue is very difficult. The development of a method for probing cavitation, irrespective of its location in tissues, would improve the efficiency and application of ultrasound in the clinic. A synchrotron x-ray imaging technique, which is capable of detecting cavitation bubbles induced in water by a sonochemistry system, is reported here; this could possibly be extended to the study of therapeutic ultrasound in tissues. The two different x-ray imaging techniques of Analyzer Based Imaging (ABI) and phase contrast imaging (PCI) were examined in order to detect ultrasound induced cavitation bubbles. Cavitation was not observed by PCI, however it was detectable with ABI. Acoustic cavitation was imaged at six different acoustic power levels and six different locations through the acoustic beam in water at a fixed power level. The results indicate the potential utility of this technique for cavitation studies in tissues, but it is time consuming. This may be improved by optimizing the imaging method.

  14. Research on axial thrust of the waterjet pump based on CFD under cavitation conditions

    NASA Astrophysics Data System (ADS)

    Shen, Z. H.; Pan, Z. Y.

    2015-01-01

    Based on RANS equations, performance of a contra-rotating axial-flow waterjet pump without hydrodynamic cavitation state had been obtained combined with shear stress transport turbulence model. Its cavitation hydrodynamic performance was calculated and analysed with mixture homogeneous flow cavitation model based on Rayleigh-Plesset equations. The results shows that the cavitation causes axial thrust of waterjet pump to drop. Furthermore, axial thrust and head cavitation characteristic curve is similar. However, the drop point of the axial thrust is postponed by 5.1% comparing with one of head, and the critical point of the axial thrust is postponed by 2.6%.

  15. Investigation on the cavitation effect of underwater shock near different boundaries

    NASA Astrophysics Data System (ADS)

    Xiao, Wei; Wei, Hai-peng; Feng, Liang

    2017-08-01

    When the shock wave of underwater explosion propagates to the surfaces of different boundaries, it gets reflected. Then, a negative pressure area is formed by the superposition of the incident wave and reflected wave. Cavitation occurs when the value of the negative pressure falls below the vapor pressure of water. An improved numerical model based on the spectral element method is applied to investigate the cavitation effect of underwater shock near different boundaries, mainly including the feature of cavitation effect near different boundaries and the influence of different parameters on cavitation effect. In the implementation of the improved numerical model, the bilinear equation of state is used to deal with the fluid field subjected to cavitation, and the field separation technique is employed to avoid the distortion of incident wave propagating through the mesh and the second-order doubly asymptotic approximation is applied to simulate the non-reflecting boundary. The main results are as follows. As the peak pressure and decay constant of shock wave increases, the range of cavitation domain increases, and the duration of cavitation increases. As the depth of water increases, the influence of cavitation on the dynamic response of spherical shell decreases.

  16. Application of Cavitation Promoting Surfaces in Management of Acute Ischemic Stroke

    PubMed Central

    Soltani, Azita

    2012-01-01

    High frequency, low intensity ultrasound has the potential to accelerate the clearance of thrombotic occlusion in the absence of cavitation. At high frequency ultrasound, high acoustic pressures, > 5.2 MPa, are required to generate cavitation in thrombus. The focus of this study was to reduce the cavitation threshold by applying materials with appropriate nucleation sites at the transducer-thrombus boundary to further augment sonothrombolysis. Heterogeneous and homogenous nucleation sites were generated on the outer surface of a polyimide tube (PI) using microfringed (MPI) and laser induced (LPI) microcavities. The cavitation threshold of these materials was determined using a passive cavitation detection system. Furthermore, the biological impact of both materials was investigated in vitro. The results revealed that both MPI and LPI have the potential to induce cavitation at acoustic pressure levels as low as 2.3 MPa. In the presence of cavitation, thrombolysis rate could be enhanced by up to 2 times without any evidence of hemolysis that is generally associated with cavitation activities in blood. A prototype ultrasonic catheter operating at 1.7MHz frequency and acoustic pressure of 2.3MPa with either of MPI or LPI could be considered as a viable option for treatment of acute ischemic stroke. PMID:23141666

  17. An objective comparison of commercially-available cavitation meters.

    PubMed

    Sarno, Daniel; Hodnett, Mark; Wang, Lian; Zeqiri, Bajram

    2017-01-01

    With a number of cavitation meters on the market which claim to characterise fields in ultrasonic cleaning baths, this paper provides an objective comparison of a selection of these devices and establishes the extent to which their claims are met. The National Physical Laboratory's multi-frequency ultrasonic reference vessel provided the stable 21.06kHz field, above and below the inertial cavitation threshold, as a test bed for the sensor comparison. Measurements from these devices were evaluated in relation to the known acoustic pressure distribution in the cavitating vessel as a means of identifying the mode of operation of the sensors and to examine the particular indicator of cavitation activity which they deliver. Through the comparison with megahertz filtered acoustic signals generated by inertial cavitation, it was determined that the majority of the cavitation meters used in this study responded to acoustic pressure generated by the direct applied acoustic field and therefore tended to overestimate the occurrence of cavitation within the vessel, giving non-zero responses under conditions when there was known to be no inertial cavitation occurring with the reference vessel. This has implications for interpreting the data they provide in user applications. Copyright © 2016. Published by Elsevier B.V.

  18. Capability evaluation of ultrasonic cavitation peening at different standoff distances.

    PubMed

    Bai, Fushi; Saalbach, Kai-Alexander; Long, Yangyang; Twiefel, Jens; Wallaschek, Jörg

    2018-03-01

    Ultrasonic cavitation peening is a novel surface treatment technology which utilizes the effect of cavitation bubble collapses to improve the properties of metal surfaces. In order to obtain high impact during ultrasonic cavitation peening, a small standoff distance between a sound radiator and a rigid reflector (the surface of treated specimen) is necessary. However, the effects of different standoff distances on the capability of ultrasonic cavitation peening are not yet clear. In this paper, a simplified model was developed to evaluate the cavitation capability at different standoff distances. Meanwhile, to validate the theoretical model, the plastic deformation or erosion on the peening surface before and after treatment were compared. It was found that at a very small standoff distance the impact pressure generated by cavitation bubbles did not cause much deformation or erosion, as the dynamics of cavitation bubbles was limited. At a large standoff distance, due to much attenuation of sound propagation in the bubbly liquid, little impact pressure was generated by the collapse of cavitation bubbles and reached the treated surface. A fixed vibration amplitude, however, corresponded to a standoff distance which caused the largest deformation or erosion on the treated surface. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Stabilizing in vitro ultrasound-mediated gene transfection by regulating cavitation.

    PubMed

    Lo, Chia-Wen; Desjouy, Cyril; Chen, Shing-Ru; Lee, Jyun-Lin; Inserra, Claude; Béra, Jean-Christophe; Chen, Wen-Shiang

    2014-03-01

    It is well known that acoustic cavitation can facilitate the inward transport of genetic materials across cell membranes (sonoporation). However, partially due to the unstationary behavior of the initiation and leveling of cavitation, the sonoporation effect is usually unstable, especially in low intensity conditions. A system which is able to regulate the cavitation level during sonication by modulating the applied acoustic intensity with a feedback loop is implemented and its effect on in vitro gene transfection is tested. The regulated system provided better time stability and reproducibility of the cavitation levels than the unregulated conditions. Cultured hepatoma cells (BNL) mixed with 10 μg luciferase plasmids are exposed to 1-MHz pulsed ultrasound with or without cavitation regulation, and the gene transfection efficiency and cell viability are subsequently assessed. Experimental results show that for all exposure intensities (low, medium, and high), stable and intensity dependent, although not higher, gene expression could be achieved in the regulated cavitation system than the unregulated conditions. The cavitation regulation system provides a better control of cavitation and its bioeffect which are crucial important for clinical applications of ultrasound-mediated gene transfection. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Mapping cavitation activity around dental ultrasonic tips.

    PubMed

    Walmsley, A Damien; Lea, Simon C; Felver, Bernhard; King, David C; Price, Gareth J

    2013-05-01

    Cavitation arising within the water around the oscillating ultrasonic scaler tip is an area that may lead to advances in enhancing biofilm removal. The aim of this study is to map the occurrence of cavitation around scaler tips under loaded conditions. Two designs of piezoelectric ultrasonic scaling probes were evaluated with a scanning laser vibrometer and luminol dosimetric system under loaded (100 g/200 g) and unloaded conditions. Loads were applied to the probe tips via teeth mounted in a load-measuring apparatus. There was a positive correlation between probe displacement amplitude and cavitation production for ultrasonic probes. The position of cavitation at the tip of each probe was greater under loaded conditions than unloaded and for the longer P probe towards the tip. Whilst increasing vibration displacement amplitude of ultrasonic scalers increases the occurrence of cavitation, factors such as the length of the probe influence the amount of cavitation activity generated. The application of load affects the production of cavitation at the most clinically relevant area-the tip. Loading and the design of ultrasonic scalers lead to maximising the occurrence of the cavitation at the tip and enhance the cleaning efficiency of the scaler.

  1. Detection of cavitation vortex in hydraulic turbines using acoustic techniques

    NASA Astrophysics Data System (ADS)

    Candel, I.; Bunea, F.; Dunca, G.; Bucur, D. M.; Ioana, C.; Reeb, B.; Ciocan, G. D.

    2014-03-01

    Cavitation phenomena are known for their destructive capacity in hydraulic machineries and are caused by the pressure decrease followed by an implosion when the cavitation bubbles find an adverse pressure gradient. A helical vortex appears in the turbine diffuser cone at partial flow rate operation and can be cavitating in its core. Cavity volumes and vortex frequencies vary with the under-pressure level. If the vortex frequency comes close to one of the eigen frequencies of the turbine, a resonance phenomenon may occur, the unsteady fluctuations can be amplified and lead to important turbine and hydraulic circuit damage. Conventional cavitation vortex detection techniques are based on passive devices (pressure sensors or accelerometers). Limited sensor bandwidths and low frequency response limit the vortex detection and characterization information provided by the passive techniques. In order to go beyond these techniques and develop a new active one that will remove these drawbacks, previous work in the field has shown that techniques based on acoustic signals using adapted signal content to a particular hydraulic situation, can be more robust and accurate. The cavitation vortex effects in the water flow profile downstream hydraulic turbines runner are responsible for signal content modifications. Basic signal techniques use narrow band signals traveling inside the flow from an emitting transducer to a receiving one (active sensors). Emissions of wide band signals in the flow during the apparition and development of the vortex embeds changes in the received signals. Signal processing methods are used to estimate the cavitation apparition and evolution. Tests done in a reduced scale facility showed that due to the increasing flow rate, the signal -- vortex interaction is seen as modifications on the received signal's high order statistics and bandwidth. Wide band acoustic transducers have a higher dynamic range over mechanical elements; the system's reaction time is reduced, resulting in a faster detection of the unwanted effects. The paper will present an example of this new investigation technique on a vortex generator in the test facility that belongs to ICPE- CA.

  2. Monitoring Cavitation in HIFU as an Aid to Assisting Treatment

    NASA Astrophysics Data System (ADS)

    Hsieh, Chang-yu; Smith, Penny Probert; Kennedy, James; Leslie, Thomas

    2007-05-01

    Rapid hypothermia resulting in tissue necrosis is often associated with bubble activity (normally from cavitation) in HIFU treatment. Indeed in some HIFU protocols, the evidence of cavitation is taken as an indicator of tissue lesions. In this paper we discuss two methods to delineate reliably the region in which cavitation occurs, so that a history of the cavitation events can be provided automatically during treatment. Results are shown on simulated images and from a clinical treatment session.

  3. An Experimental Study of Cavitation Detection in a Centrifugal Pump Using Envelope Analysis

    NASA Astrophysics Data System (ADS)

    Tan, Chek Zin; Leong, M. Salman

    Cavitation represents one of the most common faults in pumps and could potentially lead to a series of failure in mechanical seal, impeller, bearing, shaft, motor, etc. In this work, an experimental rig was setup to investigate cavitation detection using vibration envelope analysis method, and measured parameters included sound, pressure and flow rate for feasibility of cavitation detection. The experiment testing included 3 operating points of the centrifugal pump (B.E.P, 90% of B.E.P and 80% of B.E.P). Suction pressure of the centrifugal pump was decreased gradually until the inception point of cavitation. Vibration measurements were undertaken at various locations including casing, bearing, suction and discharge flange of the centrifugal pump. Comparisons of envelope spectrums under cavitating and non-cavitating conditions were presented. Envelope analysis was proven useful in detecting cavitation over the 3 testing conditions. During the normal operating condition, vibration peak synchronous to rotational speed was more pronounced. It was however during cavitation condition, the half order sub-harmonic vibration component was clearly evident in the envelope spectrums undertaken at all measurement locations except at the pump bearing. The possible explanation of the strong sub-harmonic (½ of BPF) during cavitation existence in the centrifugal pump was due to insufficient time for the bubbles to collapse completely before the end of the single cycle.

  4. Physical and numerical investigation of the flow induced vibration of the hydrofoil

    NASA Astrophysics Data System (ADS)

    Wu, Q.; Wang, G. Y.; Huang, B.

    2016-11-01

    The objective of this paper is to investigate the flow induced vibration of a flexible hydrofoil in cavitating flows via combined experimental and numerical studies. The experiments are presented for the modified NACA66 hydrofoil made of POM Polyacetate in the closed-loop cavitation tunnel at Beijing Institute of Technology. The high-speed camera and the single point Laser Doppler Vibrometer are applied to analyze the transient flow structures and the corresponding structural vibration characteristics. The hybrid coupled fluid structure interaction model is conducted to couple the incompressible and unsteady Reynolds Averaged Navier-Stokes solver with a simplified two-degree-of-freedom structural model. The k-ω SST turbulence model with the turbulence viscosity correction and the Zwart cavitation model are introduced to the present simulations. The results showed that with the decreasing of the cavitation number, the cavitating flows display incipient cavitation, sheet cavitation, cloud cavitation and supercavitation. The vibration magnitude increases dramatically for the cloud cavitation and decline for the supercavitation. The cloud cavitation development strongly affects the vibration response, which is corresponding to the periodically developing and shedding of the large-scale cloud cavity. The main frequency of the vibration amplitude is accordance with the cavity shedding frequency and other two frequencies of the vibration amplitude are corresponding to the natural frequencies of the bending and twisting modes.

  5. Detecting cavitation in mercury exposed to a high-energy pulsed proton beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manzi, Nicholas J; Chitnis, Parag V; Holt, Ray G

    2010-01-01

    The Oak Ridge National Laboratory Spallation Neutron Source employs a high-energy pulsed proton beam incident on a mercury target to generate short bursts of neutrons. Absorption of the proton beam produces rapid heating of the mercury, resulting in the formation of acoustic shock waves and the nucleation of cavitation bubbles. The subsequent collapse of these cavitation bubbles promote erosion of the steel target walls. Preliminary measurements using two passive cavitation detectors (megahertz-frequency focused and unfocused piezoelectric transducers) installed in a mercury test target to monitor cavitation generated by proton beams with charges ranging from 0.041 to 4.1 C will bemore » reported on. Cavitation was initially detected for a beam charge of 0.082 C by the presence of an acoustic emission approximately 250 s after arrival of the incident proton beam. This emission was consistent with an inertial cavitation collapse of a bubble with an estimated maximum bubble radius of 0.19 mm, based on collapse time. The peak pressure in the mercury for the initiation of cavitation was predicted to be 0.6 MPa. For a beam charge of 0.41 C and higher, the lifetimes of the bubbles exceeded the reverberation time of the chamber (~300 s), and distinct windows of cavitation activity were detected, a phenomenon that likely resulted from the interaction of the reverberation in the chamber and the cavitation bubbles.« less

  6. Cavitation in liquid cryogens. 4: Combined correlations for venturi, hydrofoil, ogives, and pumps

    NASA Technical Reports Server (NTRS)

    Hord, J.

    1974-01-01

    The results of a series of experimental and analytical cavitation studies are presented. Cross-correlation is performed of the developed cavity data for a venturi, a hydrofoil and three scaled ogives. The new correlating parameter, MTWO, improves data correlation for these stationary bodies and for pumping equipment. Existing techniques for predicting the cavitating performance of pumping machinery were extended to include variations in flow coefficient, cavitation parameter, and equipment geometry. The new predictive formulations hold promise as a design tool and universal method for correlating pumping machinery performance. Application of these predictive formulas requires prescribed cavitation test data or an independent method of estimating the cavitation parameter for each pump. The latter would permit prediction of performance without testing; potential methods for evaluating the cavitation parameter prior to testing are suggested.

  7. A real-time controller for sustaining thermally relevant acoustic cavitation during ultrasound therapy.

    PubMed

    Hockham, Natalie; Coussios, Constantin C; Arora, Manish

    2010-12-01

    A novel method for sustaining inertial cavitation during high-intensity focused ultrasound (HIFU) exposure in an agar-based tissue-mimicking material is presented. Inertial cavitation occurs during HIFU therapy when the local rarefaction pressure exceeds the inertial cavitation threshold of the insonated medium, and is characterized by broadband acoustic emissions which can be easily detected non-invasively using a passive cavitation detector (PCD). Under the right conditions, inertial cavitation has been previously shown to greatly enhance the rate of heat deposition by redistributing part of the energy carried at the fundamental HIFU frequency to higher frequencies, which are more readily absorbed by visco-elastic media such as soft tissue. However, in the absence of any cavitation control, inertial cavitation activity at the focus decays rapidly over a few seconds of exposure because of the combined effects of cavitation nuclei depletion, bubble dissolution, bubble-bubble interactions, increased vapor pressure caused by heating, and focal shielding caused by pre-focal bubble activity. The present work describes the design, validation, and testing of a real-time adaptive controller, with integrated passive localization capabilities, for sustaining inertial cavitation within the focal region of a HIFU transducer by modulation of the HIFU amplitude. Use of the controller in agar gel, originally at room temperature, has enabled therapeutically relevant temperatures in excess of 55°C to be maintained continuously in the focal region for more than 20 s using significantly less acoustic energy than is required to achieve the same temperature rise in the absence of cavitation control.

  8. Longitudinal associations between children’s dental caries and risk factors

    PubMed Central

    Chankanka, Oitip; Cavanaugh, Joseph E.; Levy, Steven M.; Marshall, Teresa A.; Warren, John J; Broffitt, Barbara; Kolker, Justine L.

    2015-01-01

    Dental caries is a common disease in children of all ages. It is desirable to know whether children with primary, mixed and permanent dentitions share risk factors for cavitated and non-cavitated caries. Objective To assess the longitudinal associations between caries outcomes and modifiable risk factors. Methods One hundred and fifty-six children in the Iowa Fluoride Study met inclusion criteria of three dental examinations and caries-related risk factor assessments preceding each examination. Surface-specific counts of new non-cavitated caries and cavitated caries at the primary (Exam 1: age 5), mixed (Exam 2: age 9) and permanent (Exam 3: age 13) dentition examinations were outcome variables. Explanatory variables were caries-related factors, including averaged beverage exposure frequencies, toothbrushing frequencies, and composite water fluoride levels collected from 3–5, 6–8, and 11–13 years, dentition category, socioeconomic status and gender. Generalized linear mixed models (GLMMs) were used to explore the relationships between new non-cavitated or cavitated caries and caries-related variables. Results Greater frequency of 100% juice exposure was significantly associated with fewer non-cavitated and cavitated caries surfaces. Greater toothbrushing frequency and high SES were significantly associated with fewer new non-cavitated caries. Children had significantly more new cavitated caries surfaces at the mixed dentition examination than at the primary and permanent dentition examinations. Conclusions There were common caries-related factors for more new non-cavitated caries across the three exams, including less frequent 100% juice exposure, lower toothbrushing frequency and lower socioeconomic status. Less frequent 100% juice exposures might be associated with higher exposures to several other cariogenic beverages. PMID:22320287

  9. Characterization of cavitational activity in lithotripsy fields using a robust electromagnetic probe.

    PubMed

    Pye, S D; Dineley, J A

    1999-03-01

    A robust electromagnetic probe has been used to investigate cavitational activity in vitro in the fields of two extracorporeal lithotripters and one intracorporeal lithotripter. Some aspects of the electromagnetic probe design and characteristics are described. A series of experiments have been carried out with results indicating that the probe head moves in response to the pressure gradient generated by radial motion of cavitation bubbles. Empirical expressions have been derived for the cavitational force acting on the probe head, and for the low-frequency sawtooth pressure wave generated by inertial cavitation. This is the first time that the existence of a low-frequency sawtooth wave produced by inertial cavitation has been described. A linear relationship exists between the negative pressure amplitude of the sawtooth wave and the lifetime of the bubbles. Close to the cavitation site, substantial negative pressure is maintained throughout bubble expansion. This can easily exceed the tensile strength of urinary calculi, and may be considered to be an important mechanism for disintegrating these relatively weak structures. A pilot study has also been carried out involving three patients treated by extracorporeal lithotripsy. Signals similar to those recorded during the in vitro cavitation experiments were detected. We conclude that the electromagnetic probe is capable of detecting and quantifying aspects of cavitational activity in vitro, and potentially also in vivo. The observation that the probe responds directly to the motion of cavitation bubbles, coupled with its ability to detect cavitation at a distance, give it the potential for use in a range of medical and industrial applications.

  10. Loss of echogenicity and onset of cavitation from echogenic liposomes: pulse repetition frequency independence

    PubMed Central

    Radhakrishnan, Kirthi; Haworth, Kevin J; Peng, Tao; McPherson, David D.; Holland, Christy K.

    2014-01-01

    Echogenic liposomes (ELIP) are being developed for the early detection and treatment of atherosclerotic lesions. An 80% loss of echogenicity of ELIP (Radhakrishnan et al. 2013) has been shown to be concomitant with the onset of stable and inertial cavitation. The ultrasound pressure amplitude at which this occurs is weakly dependent on pulse duration. Smith et al. (2007) have reported that the rapid fragmentation threshold of ELIP (based on changes in echogenicity) is dependent on the insonation pulse repetition frequency (PRF). The current study evaluates the relationship between loss of echogenicity and cavitation emissions from ELIP insonified by duplex Doppler pulses at four PRFs (1.25 kHz, 2.5 kHz, 5 kHz, and 8.33 kHz). Loss of echogenicity was evaluated on B-mode images of ELIP. Cavitation emissions from ELIP were recorded passively on a focused single-element transducer and a linear array. Emissions recorded by the linear array were beamformed and the spatial widths of stable and inertial cavitation emissions were compared to the calibrated azimuthal beamwidth of the Doppler pulse exceeding the stable and inertial cavitation thresholds. The inertial cavitation thresholds had a very weak dependence on PRF and stable cavitation thresholds were independent of PRF. The spatial widths of the cavitation emissions recorded by the passive cavitation imaging system agreed with the calibrated Doppler beamwidths. The results also show that 64%–79% loss of echogenicity can be used to classify the presence or absence of cavitation emissions with greater than 80% accuracy. PMID:25438849

  11. Loss of echogenicity and onset of cavitation from echogenic liposomes: pulse repetition frequency independence.

    PubMed

    Radhakrishnan, Kirthi; Haworth, Kevin J; Peng, Tao; McPherson, David D; Holland, Christy K

    2015-01-01

    Echogenic liposomes (ELIP) are being developed for the early detection and treatment of atherosclerotic lesions. An 80% loss of echogenicity of ELIP has been found to be concomitant with the onset of stable and inertial cavitation. The ultrasound pressure amplitude at which this occurs is weakly dependent on pulse duration. It has been reported that the rapid fragmentation threshold of ELIP (based on changes in echogenicity) is dependent on the insonation pulse repetition frequency (PRF). The study described here evaluates the relationship between loss of echogenicity and cavitation emissions from ELIP insonified by duplex Doppler pulses at four PRFs (1.25, 2.5, 5 and 8.33 kHz). Loss of echogenicity was evaluated on B-mode images of ELIP. Cavitation emissions from ELIP were recorded passively on a focused single-element transducer and a linear array. Emissions recorded by the linear array were beamformed, and the spatial widths of stable and inertial cavitation emissions were compared with the calibrated azimuthal beamwidth of the Doppler pulse exceeding the stable and inertial cavitation thresholds. The inertial cavitation thresholds had a very weak dependence on PRF, and stable cavitation thresholds were independent of PRF. The spatial widths of the cavitation emissions recorded by the passive cavitation imaging system agreed with the calibrated Doppler beamwidths. The results also indicate that 64%-79% loss of echogenicity can be used to classify the presence or absence of cavitation emissions with greater than 80% accuracy. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  12. Anaerobic Digestion of Cattle Manure Influenced by Swirling Jet Induced Hydrodynamic Cavitation.

    PubMed

    Langone, Michela; Soldano, Mariangela; Fabbri, Claudio; Pirozzi, Francesco; Andreottola, Gianni

    2018-04-01

    In this work, a modified swirling jet-induced cavitation has been employed for increasing anaerobic digestion efficiency of cattle manure. The hydrodynamic cavitation (HC) treatment improved the organic matter solubilization and the anaerobic biodegradability of cattle manure. The degree of disintegration increased by 5.8, 8.9, and 15.8% after the HC treatment at 6.0, 7.0, and 8.0 bars, respectively. However, the HC treatment at 7.0 bars had better results in terms of methane production. This result may be attributed to the possible formation of toxic and refractory compounds at higher inlet pressures, which could inhibit the methanization process. Further, total Kjeldahl nitrogen content was found to decrease with increasing inlet pressures, as the pH and the turbulent mixing favored the ammonia stripping processes. HC treatment decreased the viscosity of the treated cattle manure, favoring the manure pumping and mixing. Considerations on the energy input due to the HC pre-treatment and the energy output due to the enhanced methane yield have been presented. A positive energy balance can be obtained looking at the improved operational practices in the anaerobic digesters after the implementation of the HC pre-treatment.

  13. Biological efficacy and toxic effect of emergency water disinfection process based on advanced oxidation technology.

    PubMed

    Tian, Yiping; Yuan, Xiaoli; Xu, Shujing; Li, Rihong; Zhou, Xinying; Zhang, Zhitao

    2015-12-01

    An innovative and removable water treatment system consisted of strong electric field discharge and hydrodynamic cavitation based on advanced oxidation technologies was developed for reactive free radicals producing and waterborne pathogens eliminating in the present study. The biological efficacy and toxic effects of this advanced oxidation system were evaluated during water disinfection treatments. Bench tests were carried out with synthetic microbial-contaminated water, as well as source water in rainy season from a reservoir of Dalian city (Liaoning Province, China). Results showed that high inactivation efficiency of Escherichia coli (>5 log) could be obtained for synthetic contaminated water at a low concentration (0.5-0.7 mg L(-1)) of total oxidants in 3-10 s. The numbers of wild total bacteria (108 × 10(3) CFU mL(-1)) and total coliforms (260 × 10(2) MPN 100 mL(-1)) in source water greatly reduced to 50 and 0 CFU mL(-1) respectively after treated by the advanced oxidation system, which meet the microbiological standards of drinking water, and especially that the inactivation efficiency of total coliforms could reach 100%. Meanwhile, source water qualities were greatly improved during the disinfection processes. The values of UV254 in particular were significantly reduced (60-80%) by reactive free radicals. Moreover, the concentrations of possible disinfection by-products (formaldehyde and bromide) in treated water were lower than detection limits, indicating that there was no harmful effect on water after the treatments. These investigations are helpful for the ecotoxicological studies of advanced oxidation system in the treatments of chemical polluted water or waste water. The findings of this work suggest that the developed water treatment system is ideal in the acute phases of emergencies, which also could offer additional advantages over a wide range of applications in water pollution control.

  14. The singing vortex.

    PubMed

    Arndt, R; Pennings, P; Bosschers, J; van Terwisga, T

    2015-10-06

    Marine propellers display several forms of cavitation. Of these, propeller-tip vortex cavitation is one of the important factors in propeller design. The dynamic behaviour of the tip vortex is responsible for hull vibration and noise. Thus, cavitation in the vortices trailing from tips of propeller blades has been studied extensively. Under certain circumstances cavitating vortices have been observed to have wave-like disturbances on the surfaces of vapour cores. Intense sound at discrete frequencies can result from a coupling between tip vortex disturbances and oscillating sheet cavitation on the surfaces of the propeller blades. This research article focuses on the dynamics of vortex cavitation and more in particular on the energy and frequency content of the radiated pressures.

  15. The singing vortex

    PubMed Central

    Arndt, R.; Pennings, P.; Bosschers, J.; van Terwisga, T.

    2015-01-01

    Marine propellers display several forms of cavitation. Of these, propeller-tip vortex cavitation is one of the important factors in propeller design. The dynamic behaviour of the tip vortex is responsible for hull vibration and noise. Thus, cavitation in the vortices trailing from tips of propeller blades has been studied extensively. Under certain circumstances cavitating vortices have been observed to have wave-like disturbances on the surfaces of vapour cores. Intense sound at discrete frequencies can result from a coupling between tip vortex disturbances and oscillating sheet cavitation on the surfaces of the propeller blades. This research article focuses on the dynamics of vortex cavitation and more in particular on the energy and frequency content of the radiated pressures. PMID:26442147

  16. A study to determine whether cavitation occurs around dental ultrasonic scaling instruments.

    PubMed

    Lea, S C; Price, G J; Walmsley, A D

    2005-02-01

    The aim of this investigation was to determine if cavitation occurred around dental ultrasonic scalers and to estimate the amount of cavitation occurring. Three styles of tip (3 x TFI-10, 3 x TFI-3, 3 x TFI-1) were used, in conjunction with a Cavitron SPS ultrasonic generator (Dentsply, USA), to insonate terephthalic acid solution. The hydroxyl radical, [*OH], concentration, produced due to cavitation from the scaler tips, was monitored by fluorescence spectroscopy. Cavitational activity was enhanced at higher power settings and at longer operating times. The tip dimensions and geometry as well as the generator power setting are both important factors that affect the production of cavitation.

  17. Three-dimensional numerical simulations of turbulent cavitating flow in a rectangular channel

    NASA Astrophysics Data System (ADS)

    Iben, Uwe; Makhnov, Andrei; Schmidt, Alexander

    2018-05-01

    Cavitation is a phenomenon of formation of bubbles (cavities) in liquid as a result of pressure drop. Cavitation plays an important role in a wide range of applications. For example, cavitation is one of the key problems of design and manufacturing of pumps, hydraulic turbines, ship's propellers, etc. Special attention is paid to cavitation erosion and to performance degradation of hydraulic devices (noise, fluctuations of the mass flow rate, etc.) caused by the formation of a two-phase system with an increased compressibility. Therefore, development of a model to predict cavitation inception and collapse of cavities in high-speed turbulent flows is an important fundamental and applied task. To test the algorithm three-dimensional simulations of turbulent flow of a cavitating liquid in a rectangular channel have been conducted. The obtained results demonstrate the efficiency and robustness of the formulated model and the algorithm.

  18. Theoretical and experimental comparison of vapor cavitation in dynamically loaded journal bearings

    NASA Astrophysics Data System (ADS)

    Brewe, D. E.; Hamrock, B. J.; Jacobson, B. A.

    Vapor cavitation for a submerged journal bearing under dynamically loaded conditions was investigated. The observation of vapor cavitation in the laboratory was done by high-speed photography. It was found that vapor cavitation occurs when the tensile stress applied to the oil exceeded the tensile strength of the oil or the binding of the oil to the surface. The theoretical solution to the Reynolds equation is determined numerically using a moving boundary algorithm. This algorithm conserves mass throughout the computational domain including the region of cavitation and its boundaries. An alternating direction implicit (MDI) method is used to effect the time march. A rotor undergoing circular whirl was studied. Predicted cavitation behavior was analyzed by three-dimensional computer graphic movies. The formation, growth, and collapse of the bubble in response to the dynamic conditions is shown. For the same conditions of dynamic loading, the cavitation bubble was studied in the laboratory using high-speed photography.

  19. Hydrodynamic cavitation in Stokes flow of anisotropic fluids.

    PubMed

    Stieger, Tillmann; Agha, Hakam; Schoen, Martin; Mazza, Marco G; Sengupta, Anupam

    2017-05-30

    Cavitation, the nucleation of vapour in liquids, is ubiquitous in fluid dynamics, and is often implicated in a myriad of industrial and biomedical applications. Although extensively studied in isotropic liquids, corresponding investigations in anisotropic liquids are largely lacking. Here, by combining liquid crystal microfluidic experiments, nonequilibrium molecular dynamics simulations and theoretical arguments, we report flow-induced cavitation in an anisotropic fluid. The cavitation domain nucleates due to sudden pressure drop upon flow past a cylindrical obstacle within a microchannel. For an anisotropic fluid, the inception and growth of the cavitation domain ensued in the Stokes regime, while no cavitation was observed in isotropic liquids flowing under similar hydrodynamic parameters. Using simulations we identify a critical value of the Reynolds number for cavitation inception that scales inversely with the order parameter of the fluid. Strikingly, the critical Reynolds number for anisotropic fluids can be 50% lower than that of isotropic fluids.

  20. Hydrodynamic cavitation in Stokes flow of anisotropic fluids

    PubMed Central

    Stieger, Tillmann; Agha, Hakam; Schoen, Martin; Mazza, Marco G.; Sengupta, Anupam

    2017-01-01

    Cavitation, the nucleation of vapour in liquids, is ubiquitous in fluid dynamics, and is often implicated in a myriad of industrial and biomedical applications. Although extensively studied in isotropic liquids, corresponding investigations in anisotropic liquids are largely lacking. Here, by combining liquid crystal microfluidic experiments, nonequilibrium molecular dynamics simulations and theoretical arguments, we report flow-induced cavitation in an anisotropic fluid. The cavitation domain nucleates due to sudden pressure drop upon flow past a cylindrical obstacle within a microchannel. For an anisotropic fluid, the inception and growth of the cavitation domain ensued in the Stokes regime, while no cavitation was observed in isotropic liquids flowing under similar hydrodynamic parameters. Using simulations we identify a critical value of the Reynolds number for cavitation inception that scales inversely with the order parameter of the fluid. Strikingly, the critical Reynolds number for anisotropic fluids can be 50% lower than that of isotropic fluids. PMID:28555615

  1. A physics based multiscale modeling of cavitating flows.

    PubMed

    Ma, Jingsen; Hsiao, Chao-Tsung; Chahine, Georges L

    2017-03-02

    Numerical modeling of cavitating bubbly flows is challenging due to the wide range of characteristic lengths of the physics at play: from micrometers (e.g., bubble nuclei radius) to meters (e.g., propeller diameter or sheet cavity length). To address this, we present here a multiscale approach which integrates a Discrete Singularities Model (DSM) for dispersed microbubbles and a two-phase Navier Stokes solver for the bubbly medium, which includes a level set approach to describe large cavities or gaseous pockets. Inter-scale schemes are used to smoothly bridge the two transitioning subgrid DSM bubbles into larger discretized cavities. This approach is demonstrated on several problems including cavitation inception and vapor core formation in a vortex flow, sheet-to-cloud cavitation over a hydrofoil, cavitation behind a blunt body, and cavitation on a propeller. These examples highlight the capabilities of the developed multiscale model in simulating various form of cavitation.

  2. Theoretical and experimental comparison of vapor cavitation in dynamically loaded journal bearings

    NASA Technical Reports Server (NTRS)

    Brewe, D. E.; Hamrock, B. J.; Jacobson, B. A.

    1985-01-01

    Vapor cavitation for a submerged journal bearing under dynamically loaded conditions was investigated. The observation of vapor cavitation in the laboratory was done by high-speed photography. It was found that vapor cavitation occurs when the tensile stress applied to the oil exceeded the tensile strength of the oil or the binding of the oil to the surface. The theoretical solution to the Reynolds equation is determined numerically using a moving boundary algorithm. This algorithm conserves mass throughout the computational domain including the region of cavitation and its boundaries. An alternating direction implicit (MDI) method is used to effect the time march. A rotor undergoing circular whirl was studied. Predicted cavitation behavior was analyzed by three-dimensional computer graphic movies. The formation, growth, and collapse of the bubble in response to the dynamic conditions is shown. For the same conditions of dynamic loading, the cavitation bubble was studied in the laboratory using high-speed photography.

  3. Compressive spherical beamforming for localization of incipient tip vortex cavitation.

    PubMed

    Choo, Youngmin; Seong, Woojae

    2016-12-01

    Noises by incipient propeller tip vortex cavitation (TVC) are generally generated at regions near the propeller tip. Localization of these sparse noises is performed using compressive sensing (CS) with measurement data from cavitation tunnel experiments. Since initial TVC sound radiates in all directions as a monopole source, a sensing matrix for CS is formulated by adopting spherical beamforming. CS localization is examined with known source acoustic measurements, where the CS estimated source position coincides with the known source position. Afterwards, CS is applied to initial cavitation noise cases. The result of cavitation localization was detected near the upper downstream area of the propeller and showed less ambiguity compared to Bartlett spherical beamforming. Standard constraint in CS was modified by exploiting the physical features of cavitation to suppress remaining ambiguity. CS localization of TVC using the modified constraint is shown according to cavitation numbers and compared to high-speed camera images.

  4. Cavitation measurement during sonic and ultrasonic activated irrigation.

    PubMed

    Macedo, Ricardo; Verhaagen, Bram; Rivas, David Fernandez; Versluis, Michel; Wesselink, Paul; van der Sluis, Luc

    2014-04-01

    The aims of this study were to quantify and to visualize the possible occurrence of transient cavitation (bubble formation and implosion) during sonic and ultrasonic (UAI) activated irrigation. The amount of cavitation generated around several endodontic instruments was measured by sonochemiluminescence dosimetry inside 4 root canal models of human dimensions and varying complexity. Furthermore, the spatial distribution of the sonochemiluminescence in the root canal was visualized with long-exposure photography. Instrument oscillation frequency, ultrasonic power, and file taper influenced the occurrence and amount of cavitation. In UAI, cavitation was distributed between the file and the wall extending beyond the file and inside lateral canals/isthmuses. In sonic activated irrigation, no cavitation was detected. Cavitation was shown to occur in UAI at clinically relevant ultrasonic power settings in both straight and curved canals but not around sonically oscillating instruments, driven at their highest frequency. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  5. Validity of Molecular Tagging Velocimetry in a Cavitating Flow for Turbopump Analysis

    NASA Astrophysics Data System (ADS)

    Kuzmich, Kayla; Bohl, Doug

    2012-11-01

    This research establishes multi-phase molecular tagging velocimetry (MTV) use and explores its limitations. The flow conditions and geometry in the inducer of an upper stage liquid Oxygen (LOX)/LH2 engine frequently cause cavitation which decreases turbopump performance. Complications arise in performing experiments in liquid hydrogen and oxygen due to high costs, high pressures, extremely low fluid temperatures, the presence of cavitation, and associated safety risks. Due to the complex geometry and hazardous nature of the fluids, a simplified throat geometry with water as a simulant fluid is used. Flow characteristics are measured using MTV, a noninvasive flow diagnostic technique. MTV is found to be an applicable tool in cases of low cavitation. Highly cavitating flows reflect and scatter most of the laser beam disallowing penetration into the cavitation cloud. However, data can be obtained in high cavitation cases near the cloud boundary layer. Distribution A: Public Release, Public Affairs Clearance Number: 12654

  6. A physics based multiscale modeling of cavitating flows

    PubMed Central

    Ma, Jingsen; Hsiao, Chao-Tsung; Chahine, Georges L.

    2018-01-01

    Numerical modeling of cavitating bubbly flows is challenging due to the wide range of characteristic lengths of the physics at play: from micrometers (e.g., bubble nuclei radius) to meters (e.g., propeller diameter or sheet cavity length). To address this, we present here a multiscale approach which integrates a Discrete Singularities Model (DSM) for dispersed microbubbles and a two-phase Navier Stokes solver for the bubbly medium, which includes a level set approach to describe large cavities or gaseous pockets. Inter-scale schemes are used to smoothly bridge the two transitioning subgrid DSM bubbles into larger discretized cavities. This approach is demonstrated on several problems including cavitation inception and vapor core formation in a vortex flow, sheet-to-cloud cavitation over a hydrofoil, cavitation behind a blunt body, and cavitation on a propeller. These examples highlight the capabilities of the developed multiscale model in simulating various form of cavitation. PMID:29720773

  7. Hydrodynamic cavitation in Stokes flow of anisotropic fluids

    NASA Astrophysics Data System (ADS)

    Stieger, Tillmann; Agha, Hakam; Schoen, Martin; Mazza, Marco G.; Sengupta, Anupam

    2017-05-01

    Cavitation, the nucleation of vapour in liquids, is ubiquitous in fluid dynamics, and is often implicated in a myriad of industrial and biomedical applications. Although extensively studied in isotropic liquids, corresponding investigations in anisotropic liquids are largely lacking. Here, by combining liquid crystal microfluidic experiments, nonequilibrium molecular dynamics simulations and theoretical arguments, we report flow-induced cavitation in an anisotropic fluid. The cavitation domain nucleates due to sudden pressure drop upon flow past a cylindrical obstacle within a microchannel. For an anisotropic fluid, the inception and growth of the cavitation domain ensued in the Stokes regime, while no cavitation was observed in isotropic liquids flowing under similar hydrodynamic parameters. Using simulations we identify a critical value of the Reynolds number for cavitation inception that scales inversely with the order parameter of the fluid. Strikingly, the critical Reynolds number for anisotropic fluids can be 50% lower than that of isotropic fluids.

  8. Enhancement of cavitation erosion resistance of 316 L stainless steel by adding molybdenum.

    PubMed

    Li, D G; Chen, D R; Liang, P

    2017-03-01

    The influence of Mo on ultrasonic cavitation erosion of 316 L stainless steel in 3.5% NaCl solution were investigated using an ultrasonic cavitation erosion (CE) facility. The morphologies of specimen after cavitation erosion were observed by scanning electron microscopy (SEM). The results showed that the addition of Mo can sharply decrease the mean depth of erosion (MDE) of 316 L SS, implying the increased resistance of cavitation erosion. In order to better understanding the influence of Mo on the cavitation erosion of 316 L SS, the semi-conductive property of passive films on 316 L SS containing different concentrations of Mo were studied by Mott-Schottky plot. Based on Mott-Schottky results and semiconductor physics, a physical model was proposed to explain the effect mechanism of Mo on cavitation erosion of 316 L SS. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Effect of ultrasonic cavitation on measurement of sound pressure using hydrophone

    NASA Astrophysics Data System (ADS)

    Thanh Nguyen, Tam; Asakura, Yoshiyuki; Okada, Nagaya; Koda, Shinobu; Yasuda, Keiji

    2017-07-01

    Effect of ultrasonic cavitation on sound pressure at the fundamental, second harmonic, and first ultraharmonic frequencies was investigated from low to high ultrasonic intensities. The driving frequencies were 22, 304, and 488 kHz. Sound pressure was measured using a needle-type hydrophone and ultrasonic cavitation was estimated from the broadband integrated pressure (BIP). With increasing square root of electric power applied to a transducer, the sound pressure at the fundamental frequency linearly increased initially, dropped at approximately the electric power of cavitation inception, and afterward increased again. The sound pressure at the second harmonic frequency was detected just below the electric power of cavitation inception. The first ultraharmonic component appeared at around the electric power of cavitation inception at 304 and 488 kHz. However, at 22 kHz, the first ultraharmonic component appeared at a higher electric power than that of cavitation inception.

  10. Observation of a cavitation cloud in tissue using correlation between ultrafast ultrasound images.

    PubMed

    Prieur, Fabrice; Zorgani, Ali; Catheline, Stefan; Souchon, Rémi; Mestas, Jean-Louis; Lafond, Maxime; Lafon, Cyril

    2015-07-01

    The local application of ultrasound is known to improve drug intake by tumors. Cavitating bubbles are one of the contributing effects. A setup in which two ultrasound transducers are placed confocally is used to generate cavitation in ex vivo tissue. As the transducers emit a series of short excitation bursts, the evolution of the cavitation activity is monitored using an ultrafast ultrasound imaging system. The frame rate of the system is several thousands of images per second, which provides several tens of images between consecutive excitation bursts. Using the correlation between consecutive images for speckle tracking, a decorrelation of the imaging signal appears due to the creation, fast movement, and dissolution of the bubbles in the cavitation cloud. By analyzing this area of decorrelation, the cavitation cloud can be localized and the spatial extent of the cavitation activity characterized.

  11. Optimal design of solenoid valve to minimize cavitation by numerical analysis

    NASA Astrophysics Data System (ADS)

    Ko, Seungbin; Jang, Ilhoon; Song, Simon

    2012-11-01

    Keeping pace with the development of clean energy, hybrid cars and electric vehicles are getting extensive attention recently. In an electronic-control brake system which is essential to those vehicles, a solenoid valve is used to control external hydraulic pressure that boosts up the driver's braking force. However, strong cavitation occurs at the narrow passage between the ball and seat of a solenoid valve due to sudden decrease in pressure, leading to severe damage to the valve. In this study, we investigate the cavitation numerically to discover geometric parameters to affect the cavitation, and an optimal design to minimize the cavitation using optimization technique. As a result, we found four parameters: seat inner radius, seat angle, seat length, and ball radius. Among them, the seat inner radius affects the cavitation most. Also, we found that preventing a sudden reduction in a flow passage is important to reduce cavitation. Finally using an evolutionary algorithm for optimization we minimized cavitation. The optimal design resulted in the maximum vapor volume of fraction of 0.04 while it was 0.7 for reference geometry.

  12. Application of X-ray micro-computed tomography on high-speed cavitating diesel fuel flows

    NASA Astrophysics Data System (ADS)

    Mitroglou, N.; Lorenzi, M.; Santini, M.; Gavaises, M.

    2016-11-01

    The flow inside a purpose built enlarged single-orifice nozzle replica is quantified using time-averaged X-ray micro-computed tomography (micro-CT) and high-speed shadowgraphy. Results have been obtained at Reynolds and cavitation numbers similar to those of real-size injectors. Good agreement for the cavitation extent inside the orifice is found between the micro-CT and the corresponding temporal mean 2D cavitation image, as captured by the high-speed camera. However, the internal 3D structure of the developing cavitation cloud reveals a hollow vapour cloud ring formed at the hole entrance and extending only at the lower part of the hole due to the asymmetric flow entry. Moreover, the cavitation volume fraction exhibits a significant gradient along the orifice volume. The cavitation number and the needle valve lift seem to be the most influential operating parameters, while the Reynolds number seems to have only small effect for the range of values tested. Overall, the study demonstrates that use of micro-CT can be a reliable tool for cavitation in nozzle orifices operating under nominal steady-state conditions.

  13. Dynamics and noise emission of laser induced cavitation bubbles in a vortical flow field

    NASA Astrophysics Data System (ADS)

    Oweis, Ghanem F.; Choi, Jaehyug; Ceccio, Steven L.

    2004-03-01

    The sound produced by the collapse of discrete cavitation bubbles was examined. Laser-generated cavitation bubbles were produced in both a quiescent and a vortical flow. The sound produced by the collapse of the cavitation bubbles was recorded, and its spectral content was determined. It was found that the risetime of the sound pulse produced by the collapse of single, spherical cavitation bubbles in quiescent fluid exceeded that of the slew rate of the hydrophone, which is consistent with previously published results. It was found that, as collapsing bubbles were deformed by the vortical flow, the acoustic impulse of the bubbles was reduced. Collapsing nonspherical bubbles often created a sound pulse with a risetime that exceeded that of the hydrophone slew rate, although the acoustic impulse created by the bubbles was influenced largely by the degree to which the bubbles became nonspherical before collapse. The noise produced by the slow growth of cavitation bubbles in the vortex core was not detectable. These results have implications for the interpretation of hydrodynamic cavitation noise produced by vortex cavitation.

  14. Cavitation control on a 2D hydrofoil through a continuous tangential injection of liquid: Experimental study

    NASA Astrophysics Data System (ADS)

    Timoshevskiy, M. V.; Zapryagaev, I. I.; Pervunin, K. S.; Markovich, D. M.

    2016-10-01

    In the paper, the possibility of active control of a cavitating flow over a 2D hydrofoil that replicates a scaled-down model of high-pressure hydroturbine guide vane (GV) was tested. The flow manipulation was implemented by a continuous tangential liquid injection at different flow rates through a spanwise slot in the foil surface. In experiments, the hydrofoil was placed in the test channel at the attack angle of 9°. Different cavitation conditions were reached by varying the cavitation number and injection velocity. In order to study time dynamics and spatial patterns of partial cavities, high-speed imaging was employed. A PIV method was used to measure the mean and fluctuating velocity fields over the hydrofoil. Hydroacoustic measurements were carried out by means of a pressure transducer to identify spectral characteristics of the cavitating flow. It was found that the present control technique is able to modify the partial cavity pattern (or even totally suppress cavitation) in case of stable sheet cavitation and change the amplitude of pressure pulsations at unsteady regimes. The injection technique makes it also possible to significantly influence the spatial distributions of the mean velocity and its turbulent fluctuations over the GV section for non-cavitating flow and sheet cavitation.

  15. Correlation between cavitation erosion resistance and cyclic mechanical properties of different metallic materials

    NASA Astrophysics Data System (ADS)

    Kaufhold, Corinna; Pöhl, Fabian; Theisen, Werner

    2017-05-01

    Machine components in contact with flowing fluids are especially prone to cavitation erosion, where plastic deformation and material loss occur due to the repeated implosion of cavitation bubbles in the vicinity of a solid surface. Identifying a correlation between experimentally derivable material properties and resistance against cavitation erosion could help improve the lifetime of cavitation-affected components. Cavitation erosion is a predominantly fatigue-driven phenomenon. In this investigation, we conducted nanoindentation experiments to examine cyclic micromechanical material properties in response to an increasing number of cycles. The experiments were performed on pure iron and different steel grades, i.e., austenitic stainless CrMnCN steels, interstitially alloyed with carbon and nitrogen. We confirmed the view, also proposed in literature, that indentation hardness is inappropriate for ordering the investigated materials by incubation period or maximum erosion rate. We found that the percentage increase of nanoindentation contact stiffness, after an increasing number of cycles, is a promising indicator in terms of the overall ranking of cavitation erosion resistance among the considered materials. Although a single cavitation impact is associated with a significantly higher strain rate than nanoindentation experiments, it is shown that the plastically deformed area around each indent exhibits indications of deformation, such as the formation of slip lines that are also observable after cavitation-induced impacts.

  16. Modeling cavitation in a rapidly changing pressure field - application to a small ultrasonic horn.

    PubMed

    Žnidarčič, Anton; Mettin, Robert; Dular, Matevž

    2015-01-01

    Ultrasonic horn transducers are frequently used in applications of acoustic cavitation in liquids. It has been observed that if the horn tip is sufficiently small and driven at high amplitude, cavitation is very strong, and the tip can be covered entirely by the gas/vapor phase for longer time intervals. A peculiar dynamics of the attached cavity can emerge with expansion and collapse at a self-generated frequency in the subharmonic range, i.e. below the acoustic driving frequency. The term "acoustic supercavitation" was proposed for this type of cavitation Žnidarčič et al. (2014) [1]. We tested several established hydrodynamic cavitation models on this problem, but none of them was able to correctly predict the flow features. As a specific characteristic of such acoustic cavitation problems lies in the rapidly changing driving pressures, we present an improved approach to cavitation modeling, which does not neglect the second derivatives in the Rayleigh-Plesset equation. Comparison with measurements of acoustic supercavitation at an ultrasonic horn of 20kHz frequency revealed a good agreement in terms of cavity dynamics, cavity volume and emitted pressure pulsations. The newly developed cavitation model is particularly suited for simulation of cavitating flow in highly fluctuating driving pressure fields. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Are flowers vulnerable to xylem cavitation during drought?

    PubMed

    Zhang, Feng-Ping; Brodribb, Timothy J

    2017-05-17

    Water stress is known to cause xylem cavitation in the leaves, roots and stems of plants, but little is known about the vulnerability of flowers to xylem damage during drought. This is an important gap in our understanding of how and when plants become damaged by water stress. Here we address fundamental questions about if and when flowers suffer cavitation damage, using a new technique of cavitation imaging to resolve the timing of cavitation in water-stressed flower petals compared with neighbouring leaves. Leaves and flowers from a sample of two herbaceous and two woody eudicots were exposed to a severe water stress while the spatial and temporal propagation of embolism through veins was recorded. Although in most cases water potentials inducing 50% embolism of herbaceous flower veins were more negative than neighbouring leaves, there was no significant difference between the average vulnerability of leaves and petals of herbaceous species. In both woody species, petals were more vulnerable to cavitation than leaves, in one case by more than 3 MPa. Early cavitation and subsequent damage of flowers in the two woody species would thus be expected to precede leaf damage during drought. Similar cavitation thresholds of flowers and leaves in the herb sample suggest that cavitation during water shortage in these species will occur simultaneously among aerial tissues. Species-specific differences in the cavitation thresholds of petals provide a new axis of variation that may explain contrasting flowering ecology among plant species. © 2017 The Author(s).

  18. Investigation of the cavitating flow in injector nozzles for diesel and biodiesel

    NASA Astrophysics Data System (ADS)

    Zhong, Wenjun; He, Zhixia; Wang, Qian; Jiang, Zhaochen; Fu, Yanan

    2013-07-01

    In diesel engines, the cavitating flow in nozzles greatly affects the fuel atomization characteristics and then the subsequent combustion and exhaust emissions. At present the biodiesel is a kind of prospective alternative fuel in diesel engines, the flow characteristics for the biodiesel fuel need to be investigated. In this paper, based on the third-generation synchrotrons of Shanghai Synchrotron Radiation facility (SSRF), a high-precision three-dimension structure of testing nozzle with detailed internal geometry information was obtained using X-ray radiography for a more accurate physical model. A flow visualization experiment system with a transparent scaled-up vertical multi-hole injector nozzle tip was setup. A high resolution and speed CCD camera equipped with a long distance microscope device was used to acquire flow images of diesel and biodiesel fuel, respectively. Then, the characteristics of cavitating flow and their effects on the fuel atomization characteristics were investigated. The experimental results show that the nozzle cavitating flow of both the diesel and biodiesel fuel could be divided into four regimes: turbulent flow, cavitation inception, development of cavitation and hydraulic flip. The critical pressures of both the cavitating flow and hydraulic flip of biodiesel are higher than those of diesel. The spray cone angle increases as the cavitation occurs, but it decreases when the hydraulic flip appears. Finally, it can be concluded that the Reynolds number decreases with the increase of cavitation number, and the discharge coefficient increases with the increase of cavitation number.

  19. Recovery performance in xylem hydraulic conductivity is correlated with cavitation resistance for temperate deciduous tree species.

    PubMed

    Ogasa, Mayumi; Miki, Naoko H; Murakami, Yuki; Yoshikawa, Ken

    2013-04-01

    Woody species hydraulically vulnerable to xylem cavitation may experience daily xylem embolism. How such species cope with the possibility of accumulated embolism is unclear. In this study, we examined seven temperate woody species to assess the hypothesis that low cavitation resistance (high vulnerability to cavitation) is compensated by high recovery performance via vessel refilling. We also evaluated leaf functional and xylem structural traits. The xylem recovery index (XRI), defined as the ratio of xylem hydraulic conductivity in plants rewatered after soil drought to that in plants under moist conditions, varied among species. The xylem water potential causing 50% loss of hydraulic conductivity (Ψ50) varied among the species studied, whereas only a slight difference was detected with respect to midday xylem water potential (Ψmin), indicating smaller hydraulic safety margins (Ψmin - Ψ50) for species more vulnerable to cavitation. Cavitation resistance (|Ψ50|) was negatively correlated with XRI across species, with cavitation-vulnerable species showing a higher performance in xylem recovery. Wood density was positively correlated with cavitation resistance and was negatively correlated with XRI. These novel results reveal that coordination exists between cavitation resistance and xylem recovery performance, in association with wood functional traits such as denser wood for cavitation-resistant xylem and less-dense but water-storable wood for refillable xylem. These findings provide insights into long-term maintenance of water transport in tree species growing under variable environmental conditions.

  20. Trans-Stent B-Mode Ultrasound and Passive Cavitation Imaging

    PubMed Central

    Haworth, Kevin J.; Raymond, Jason L.; Radhakrishnan, Kirthi; Moody, Melanie R.; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E.; Kim, Hyunggun; Mcpherson, David D.; Holland, Christy K.

    2015-01-01

    Angioplasty and stenting of a stenosed artery enable acute restoration of blood flow. However, restenosis or a lack of re-endothelization can subsequently occur depending on the stent type. Cavitation-mediated drug delivery is a potential therapy for these conditions, but requires that particular types of cavitation be induced by ultrasound insonation. Because of the heterogeneity of tissue and stochastic nature of cavitation, feedback mechanisms are needed to determine whether the sustained bubble activity is induced. The objective of this study was to determine the feasibility of passive cavitation imaging through a metal stent in a flow phantom and an animal model. In this study, an endovascular stent was deployed in a flow phantom and in porcine femoral arteries. Fluorophore-labeled echogenic liposomes, a theragnostic ultrasound contrast agent, were injected proximal to the stent. Cavitation images were obtained by passively recording and beamforming the acoustic emissions from echogenic liposomes insonified with a low-frequency (500 kHz) transducer. In vitro experiments revealed that the signal-to-noise ratio for detecting stable cavitation activity through the stent was greater than 8 dB. The stent did not significantly reduce the signal-to-noise ratio. Trans-stent cavitation activity was also detected in vivo via passive cavitation imaging when echogenic liposomes were insonified by the 500-kHz transducer. When stable cavitation was detected, delivery of the fluorophore into the arterial wall was observed. Increased echogenicity within the stent was also observed when echogenic liposomes were administered. Thus, both B-mode ultrasound imaging and cavitation imaging are feasible in the presence of an endovascular stent in vivo. Demonstration of this capability supports future studies to monitor restenosis with contrast-enhanced ultrasound and pursue image-guided ultrasound-mediated drug delivery to inhibit restenosis. PMID:26547633

  1. Incidence and clinical implication of tumor cavitation in patients with advanced non-small cell lung cancer induced by Endostar, an angiogenesis inhibitor.

    PubMed

    Huang, Chun; Wang, Xuan; Wang, Jing; Lin, Li; Liu, Zhujun; Xu, Wenjing; Wang, Liuchun; Xiao, Jianyu; Li, Kai

    2014-09-01

    Antiangiogenesis plays a key role in the treatment of non-small lung cancer (NSCLC). We observed the cavitation of lesions in patients with stage IIIB/IV NSCLC treated with Endostar and vinorelbine-cisplatin (NP) chemotherapy, and evaluated the imaging characteristics and clinical outcome of patients who developed tumor cavitation. Our study included 105 untreated NSCLC patients who received Endostar in combination with NP chemotherapy at the Tianjin Lung Cancer Center. Chest computed tomography (CT) was performed to evaluate the efficacy every two cycles. The number of activated circulating endothelial cells (aCECs) was measured by flow cytometry. Rates of tumor cavitation were documented and their clinical CT imaging data were analyzed. Tumor cavitation occurred in 11 of the 105 (10.5%) patients treated with Endostar and NP. The response rates were 37.2% (35/94) in patients without cavitation, 27.3% (3/11) evaluated by Response Evaluation Criteria in Solid Tumors, and 100.0% (11/11) if evaluated by an alternate method in patients who developed cavitation. Three of the 11 cases with cavitation had a centrally located tumor. No patients had hemoptysis or any other severe side effects. Compared with patients not developing cavitation, cavity formation resulted in a longer median survival time (13.6 vs. 11.8 months, P = 0.011) and an increase in the number of aCECs (244.4/10(5) vs. 23.3/10(5), P = 0.000). Intratumoral cavitation induced by Endostar is common in NSCLC patients, and is not correlated with squamous histology, tumor location or pulmonary hemorrhage. Cavitation might have a significant effect on the number of aCECs and overall prognosis.

  2. Clinical significance of tumor cavitation in surgically resected early-stage primary lung cancer.

    PubMed

    Tomizawa, Kenji; Shimizu, Shigeki; Ohara, Shuta; Fujino, Toshio; Nishino, Masaya; Sesumi, Yuichi; Kobayashi, Yoshihisa; Sato, Katsuaki; Chiba, Masato; Shimoji, Masaki; Suda, Kenichi; Takemoto, Toshiki; Mitsudomi, Tetsuya

    2017-10-01

    The prognostic impact of tumor cavitation is unclear in patients with early-stage primary lung cancer. The aim of the present study was to examine the clinicopathological features and prognoses of patients with pathological stage I-IIA (p-stage I-IIA) primary lung cancers harboring tumor cavitation. This study was conducted according to the eighth edition of the TNM classification for lung cancer. We examined 602 patients with p-stage I-IIA primary lung cancer out of 890 patients who underwent pulmonary resection from January 2007 through March 2014 and searched for the presence of tumor cavitation, which is defined as the presence of air space within the primary tumor. A total of 59 out of the 602 patients had tumor cavitation (10%). Compared with patients without tumor cavitation, those with tumor cavitation had a significantly higher frequency of the following characteristics: high serum carcinoembryonic antigen (CEA) level (≥5ng/ml, p=0.027), interstitial pneumonia (p=0.0001), high SUVmax value on FDG-PET scan (≥4.2, p=0.023), tumors located in the lower lobe (p=0.024), large tumor size (>3cm, p=0.002), vascular invasion (66% vs 17%, p<0.0001) and non-adenocarcinoma histology (p=0.025). The overall survival period of patients with tumor cavitation was significantly shorter than that of patients without tumor cavitation (log-rank test: p<0.0001, 5-year OS rate: 56% vs 81%). Tumor cavitation was found to be an independent and significant factor associated with poor prognosis in the multivariate analysis (hazard ratio: 1.76, 95% confidence interval: 1.02-3.10, p=0.042). Tumor cavitation is an independent factor for poor prognosis in patients with resected p-stage I-IIA primary lung cancer. Based on our analyses, patients with tumor cavitation should be regarded as a separate cohort that requires more intensive follow-up. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Laser surface alloying of FeCoCrAlNi high-entropy alloy on 304 stainless steel to enhance corrosion and cavitation erosion resistance

    NASA Astrophysics Data System (ADS)

    Zhang, S.; Wu, C. L.; Zhang, C. H.; Guan, M.; Tan, J. Z.

    2016-10-01

    FeCoCrAlNi high-entropy alloy coating was synthesized with premixed high-purity Co, Cr, Al and Ni powders on 304 stainless steel by laser surface alloying, aiming at improving corrosion and cavitation erosion resistance. Phase constituents, microstructure and microhardness were investigated using XRD, SEM, and microhardness tester, respectively. The cavitation erosion and electrochemical corrosion behavior of FeCoCrAlNi coating in 3.5% NaCl solution were also evaluated using an ultrasonic vibrator and potentiodynamic polarization measurement. Experimental results showed that with appropriate laser processing parameters, FeCoCrAlNi coating with good metallurgical bonding to the substrate could be achieved. FeCoCrAlNi coating was composed of a single BCC solid solution. The formation of simple solid solutions in HEAs was the combined effect of mixing entropy (ΔSmix), mixing enthalpy (ΔHmix), atom-size difference (δ) and valence electron concentration (VEC), and the effect of ΔSmix was much larger than that of the other factors. The microhardness of the FeCoCrAlNi coating was ~3 times that of the 304 stainless steel. Both the corrosion and cavitation erosion resistance of the coating were improved. The cavitation erosion resistance for FeCoCrAlNi HEA coating was ~7.6 times that of 304 stainless steel. The corrosion resistance was also improved as reflected by a reduction in the current density of one order of magnitude as compared with 304 stainless steel.

  4. 3-D Lagrangian-based investigations of the time-dependent cloud cavitating flows around a Clark-Y hydrofoil with special emphasis on shedding process analysis

    NASA Astrophysics Data System (ADS)

    Cheng, Huai-yu; Long, Xin-ping; Ji, Bin; Liu, Qi; Bai, Xiao-rui

    2018-02-01

    In the present paper, the unsteady cavitating flow around a 3-D Clark-Y hydrofoil is numerically investigated with the filter-based density correction model (FBDCM), a turbulence model and the Zwart-Gerber-Belamri (ZGB) cavitation model. A reasonable agreement is obtained between the numerical and experimental results. To study the complex flow structures more straightforwardly, a 3-D Lagrangian technology is developed, which can provide the particle tracks and the 3-D Lagrangian coherent structures (LCSs). Combined with the traditional methods based on the Eulerian viewpoint, this technology is used to analyze the attached cavity evolution and the re-entrant jet behavior in detail. At stage I, the collapse of the previous shedding cavity and the growth of a new attached cavity, the significant influence of the collapse both on the suction and pressure sides are captured quite well by the 3-D LCSs, which is underestimated by the traditional methods like the iso-surface of Q-criteria. As a kind of special LCSs, the arching LCSs are observed in the wake, induced by the counter-rotating vortexes. At stage II, with the development of the re-entrant jet, the influence of the cavitation on the pressure side is still not negligible. And with this 3-D Lagrangian technology, the tracks of the re-entrant jet are visualized clearly, moving from the trailing edge to the leading edge. Finally, at stage III, the re-entrant jet collides with the mainstream and finally induces the shedding. The cavitation evolution and the re-entrant jet movement in the whole cycle are well visualized with the 3-D Lagrangian technology. Moreover, the comparison between the LCSs obtained with 2-D and 3-D Lagrangian technologies indicates the advantages of the latter. It is demonstrated that the 3-D Lagrangian technology is a promising tool in the investigation of complex cavitating flows.

  5. Cellulose nanofibers from banana peels as a Pickering emulsifier: High-energy emulsification processes.

    PubMed

    Costa, Ana Letícia Rodrigues; Gomes, Andresa; Tibolla, Heloisa; Menegalli, Florencia Cecilia; Cunha, Rosiane Lopes

    2018-08-15

    Cellulose nanofibers (CNFs) from banana peels was evaluated as promising stabilizer for oil-in-water emulsions. CNFs were treated using ultrasound and high-pressure homogenizer. Changes on the size, crystallinity index and zeta potential of CNFs were associated with the intense effects of cavitation phenomenon and shear forces promoted by mechanical treatments. CNFs-stabilized emulsions were produced under the same process conditions as the particles. Coalescence phenomenon was observed in the emulsions produced using high-pressure homogenizer, whereas droplets flocculation occurred in emulsions processed by ultrasound. In the latter, coalescence stability was associated with effects of cavitation forces acting on the CNFs breakup. Thus, smaller droplets created during the ultrasonication process could be recovered by particles that acted as an effective barrier against droplets coalescence. Our results improved understanding about the relationship between the choice of emulsification process and their effects on the CNFs properties influencing the potential application of CNFs as a food emulsifier. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Prediction of Shock-Induced Cavitation in Water

    NASA Astrophysics Data System (ADS)

    Brundage, Aaron

    2013-06-01

    Fluid-structure interaction problems that require estimating the response of thin structures within fluids to shock loading has wide applicability. For example, these problems may include underwater explosions and the dynamic response of ships and submarines; and biological applications such as Traumatic Brain Injury (TBI) and wound ballistics. In all of these applications the process of cavitation, where small cavities with dissolved gases or vapor are formed as the local pressure drops below the vapor pressure due to shock hydrodynamics, can cause significant damage to the surrounding thin structures or membranes if these bubbles collapse, generating additional shock loading. Hence, a two-phase equation of state (EOS) with three distinct regions of compression, expansion, and tension was developed to model shock-induced cavitation. This EOS was evaluated by comparing data from pressure and temperature shock Hugoniot measurements for water up to 400 kbar, and data from ultrasonic pressure measurements in tension to -0.3 kbar, to simulated responses from CTH, an Eulerian, finite volume shock code. The new EOS model showed significant improvement over pre-existing CTH models such as the SESAME EOS for capturing cavitation. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy/NNSA under contract DE-AC04-94AL85000.

  7. Vortex formation with a snapping shrimp claw.

    PubMed

    Hess, David; Brücker, Christoph; Hegner, Franziska; Balmert, Alexander; Bleckmann, Horst

    2013-01-01

    Snapping shrimp use one oversized claw to generate a cavitating high speed water jet for hunting, defence and communication. This work is an experimental investigation about the jet generation. Snapping shrimp (Alpheus-bellulus) were investigated by using an enlarged transparent model reproducing the closure of the snapper claw. Flow inside the model was studied using both High-Speed Particle Image Velocimetry (HS-PIV) and flow visualization. During claw closure a channel-like cavity was formed between the plunger and the socket featuring a nozzle-type contour at the orifice. Closing the mechanism led to the formation of a leading vortex ring with a dimensionless formation number of approximate ΔT*≈4. This indicates that the claw might work at maximum efficiency, i.e. maximum vortex strength was achieved by a minimum of fluid volume ejected. The subsequent vortex cavitation with the formation of an axial reentrant jet is a reasonable explanation for the large penetration depth of the water jet. That snapping shrimp can reach with their claw-induced flow. Within such a cavitation process, an axial reentrant jet is generated in the hollow cylindrical core of the cavitated vortex that pushes the front further downstream and whose length can exceed the initial jet penetration depth by several times.

  8. Cavitation clouds created by shock scattering from bubbles during histotripsy

    PubMed Central

    Maxwell, Adam D.; Wang, Tzu-Yin; Cain, Charles A.; Fowlkes, J. Brian; Sapozhnikov, Oleg A.; Bailey, Michael R.; Xu, Zhen

    2011-01-01

    Histotripsy is a therapy that focuses short-duration, high-amplitude pulses of ultrasound to incite a localized cavitation cloud that mechanically breaks down tissue. To investigate the mechanism of cloud formation, high-speed photography was used to observe clouds generated during single histotripsy pulses. Pulses of 5−20 cycles duration were applied to a transparent tissue phantom by a 1-MHz spherically focused transducer. Clouds initiated from single cavitation bubbles that formed during the initial cycles of the pulse, and grew along the acoustic axis opposite the propagation direction. Based on these observations, we hypothesized that clouds form as a result of large negative pressure generated by the backscattering of shockwaves from a single bubble. The positive-pressure phase of the wave inverts upon scattering and superimposes on the incident negative-pressure phase to create this negative pressure and cavitation. The process repeats with each cycle of the incident wave, and the bubble cloud elongates toward the transducer. Finite-amplitude propagation distorts the incident wave such that the peak-positive pressure is much greater than the peak-negative pressure, which exaggerates the effect. The hypothesis was tested with two modified incident waves that maintained negative pressure but reduced the positive pressure amplitude. These waves suppressed cloud formation which supported the hypothesis. PMID:21973343

  9. Numerical modeling of ultrasonic cavitation in ionic liquids

    NASA Astrophysics Data System (ADS)

    Calvisi, Michael L.; Elder, Ross M.

    2017-11-01

    Ionic liquids have favorable properties for sonochemistry applications in which the high temperatures and pressures achieved by cavitation bubbles are important drivers of chemical processes. Two different numerical models are presented to simulate ultrasonic cavitation in ionic liquids, each with different capabilities and physical assumptions. A model based on a compressible form of the Rayleigh-Plesset equation (RPE) simulates ultrasonic cavitation of a spherical bubble with a homogeneous interior, incorporating evaporation and condensation at the bubble surface, and temperature-varying thermodynamic properties in the interior. A second, more computationally intensive model of a spherical bubble uses the finite element method (FEM) and accounts for spatial variations in pressure and temperature throughout the flow domain. This model provides insight into heat transfer across the bubble surface and throughout the bubble interior and exterior. Parametric studies are presented for sonochemistry applications involving ionic liquids as a solvent, examining a range of realistic ionic liquid properties and initial conditions to determine their effect on temperature and pressure. Results from the two models are presented for parametric variations including viscosity, thermal conductivity, water content of the ionic liquid solvent, acoustic frequency, and initial bubble pressure. An additional study performed with the FEM model examines thermal penetration into the surrounding ionic liquid during bubble oscillation. The results suggest the prospect of tuning ionic liquid properties for specific applications.

  10. Fast X-ray imaging of cavitating flows

    DOE PAGES

    Khlifa, Ilyass; Vabre, Alexandre; Hočevar, Marko; ...

    2017-10-20

    A new method based on ultra-fast X-ray imaging was developed in this work for simultaneous investigations of the dynamics and the structures of complex two-phase flows. Here in this paper, cavitation was created inside a millimetric 2D Venturi-type test section, while seeding particles were injected into the flow. Thanks to the phase-contrast enhancement technique provided by the APS (Advanced Photon Source) synchrotron beam, high definition X-ray images of the complex cavitating flows were obtained. These images contain valuable information about both the liquid and the gaseous phases. By means of image processing, the two phases were separated, and velocity fieldsmore » of each phase were therefore calculated using image cross-correlations. The local vapour volume fractions were also obtained thanks to the local intensity levels within the recorded images. These simultaneous measurements, provided by this new technique, afford more insight into the structure and the dynamic of two-phase flows as well as the interactions between then, and hence enable to improve our understanding of their behavior. In the case of cavitating flows inside a Venturi-type test section, the X-ray measurements demonstrates, for the first time, the presence of significant slip velocities between the phases within sheet cavities for both steady and unsteady flow configurations.« less

  11. Fast X-ray imaging of cavitating flows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khlifa, Ilyass; Vabre, Alexandre; Hočevar, Marko

    A new method based on ultra-fast X-ray imaging was developed in this work for simultaneous investigations of the dynamics and the structures of complex two-phase flows. Here in this paper, cavitation was created inside a millimetric 2D Venturi-type test section, while seeding particles were injected into the flow. Thanks to the phase-contrast enhancement technique provided by the APS (Advanced Photon Source) synchrotron beam, high definition X-ray images of the complex cavitating flows were obtained. These images contain valuable information about both the liquid and the gaseous phases. By means of image processing, the two phases were separated, and velocity fieldsmore » of each phase were therefore calculated using image cross-correlations. The local vapour volume fractions were also obtained thanks to the local intensity levels within the recorded images. These simultaneous measurements, provided by this new technique, afford more insight into the structure and the dynamic of two-phase flows as well as the interactions between then, and hence enable to improve our understanding of their behavior. In the case of cavitating flows inside a Venturi-type test section, the X-ray measurements demonstrates, for the first time, the presence of significant slip velocities between the phases within sheet cavities for both steady and unsteady flow configurations.« less

  12. Applications of Hydrofoils with Leading Edge Protuberances

    DTIC Science & Technology

    2012-03-30

    of angles of attack. Table 20 presents important hydrodynamic characteristics of the finite-span rectangular hydrofoils with cavitation . 107...Table 20. Hydrodynamic characteristics of finite-span rectangular planform hydrofoils with cavitation . Rec = 7.2 × 105 [deg−1] CLmax α...characteristics of the swept planform hydrofoils under cavitation conditions. Table 21. Hydrodynamic characteristics of swept planform hydrofoils under cavitation

  13. Observations on Rotating Cavitation and Cavitation Surge From The Development of the Fastrac Engine Turbopump

    NASA Technical Reports Server (NTRS)

    Zoladz, Thomas F.; Turner, James E. (Technical Monitor)

    2000-01-01

    The effects of rotating cavitation and cavitation surges on the Fastrac Engine Turbopump are described in a viewgraph presentation format. The bent inducer blade dilemma and observations of unsteady data and oscillation components are discussed. The pump-feed system stability modeling assessment is outlined. Recommendations are made urging further investigation.

  14. Development of a Finite Element Model for Blast Brain Injury and the Effects of CSF Cavitation

    DTIC Science & Technology

    2012-02-02

    FIGURE 1. Brain geometry from photo ( left ; Visible Human Project) and plane-strain model ( right ). Development of a Finite Element Model method in LS-Dyna...between the non-cavitating ( left ) and cavitating ( right ) models for the 500 kPa/4 ms blast condition. FIGURE 6. (a) Comparing the time-history and (b...between the non-cavitating ( left ) and cavitating ( right ) models for the 500 kPa/4 ms blast condition. PANZER et al. Brain Response to Blast Over the wide

  15. Experimental investigation on dynamic characteristics and strengthening mechanism of laser-induced cavitation bubbles.

    PubMed

    Ren, X D; He, H; Tong, Y Q; Ren, Y P; Yuan, S Q; Liu, R; Zuo, C Y; Wu, K; Sui, S; Wang, D S

    2016-09-01

    The dynamic features of nanosecond laser-induced cavitation bubbles near the light alloy boundary were investigated with the high-speed photography. The shock-waves and the dynamic characteristics of the cavitation bubbles generated by the laser were detected using the hydrophone. The dynamic features and strengthening mechanism of cavitation bubbles were studied. The strengthening mechanisms of cavitation bubble were discussed when the relative distance parameter γ was within the range of 0.5-2.5. It showed that the strengthening mechanisms caused by liquid jet or shock-waves depended on γ much. The research results provided a new strengthening method based on laser-induced cavitation shotless peening (CSP). Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Cavitation in Amorphous Solids

    NASA Astrophysics Data System (ADS)

    Guan, Pengfei; Lu, Shuo; Spector, Michael J. B.; Valavala, Pavan K.; Falk, Michael L.

    2013-05-01

    Molecular dynamics simulations of cavitation in a Zr50Cu50 metallic glass exhibit a waiting time dependent cavitation rate. On short time scales nucleation rates and critical cavity sizes are commensurate with a classical theory of nucleation that accounts for both the plastic dissipation during cavitation and the cavity size dependence of the surface energy. All but one parameter, the Tolman length, can be extracted directly from independent calculations or estimated from physical principles. On longer time scales strain aging in the form of shear relaxations results in a systematic decrease of cavitation rate. The high cavitation rates that arise due to the suppression of the surface energy in small cavities provide a possible explanation for the quasibrittle fracture observed in metallic glasses.

  17. Effect of micro-particles on cavitation erosion of Ti6Al4V alloy in sulfuric acid solution.

    PubMed

    Li, D G; Long, Y; Liang, P; Chen, D R

    2017-05-01

    The influences of micro-particles on ultrasonic cavitation erosion of Ti6Al4V alloy in 0.1M H 2 SO 4 solution were investigated using mass loss weight, scanning electron microscopy (SEM) and white light interferometer. Mass loss results revealed that the cavitation erosion damage obviously decreased with increasing particle size and mass concentration. Open circuit potential recorded during cavitation erosion shifted to positive direction with the decreased mass loss. Meanwhile, the mass loss sharply decreased with applying a positive potential during the entire ultrasonic cavitation erosion, and the relationship between the open circuit potential and the cavitation erosion resistance was discussed. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. A multimodal instrument for real-time in situ study of ultrasound and cavitation mediated drug delivery.

    PubMed

    Bian, Shuning; Seth, Anjali; Daly, Dan; Carlisle, Robert; Stride, Eleanor

    2017-03-01

    The development of a multimodal instrument capable of real-time in situ measurements of cavitation activity and effect in tissue mimicking phantoms during ultrasound and cavitation mediated drug delivery experiments is described here. The instrument features an acoustic arm that can expose phantoms to high-intensity focused-ultrasound while measuring cavitation activity and an optical arm that monitors cavitation effect using confocal microscopy. This combination of modalities allows real-time in situ characterisation of drug delivery in tissue and tissue mimicking phantoms during ultrasound and cavitation mediated drug delivery experiments. A representative result, obtained with a tissue mimicking phantom and acoustically activated droplets, is presented here as a demonstration of the instrument's capabilities and potential applications.

  19. Extension of transonic flow computational concepts in the analysis of cavitated bearings

    NASA Technical Reports Server (NTRS)

    Vijayaraghavan, D.; Keith, T. G., Jr.; Brewe, D. E.

    1990-01-01

    An analogy between the mathematical modeling of transonic potential flow and the flow in a cavitating bearing is described. Based on the similarities, characteristics of the cavitated region and jump conditions across the film reformation and rupture fronts are developed using the method of weak solutions. The mathematical analogy is extended by utilizing a few computational concepts of transonic flow to numerically model the cavitating bearing. Methods of shock fitting and shock capturing are discussed. Various procedures used in transonic flow computations are adapted to bearing cavitation applications, for example, type differencing, grid transformation, an approximate factorization technique, and Newton's iteration method. These concepts have proved to be successful and have vastly improved the efficiency of numerical modeling of cavitated bearings.

  20. High-temperature deformation and microstructural analysis for Si3N4-Sc2O3

    NASA Technical Reports Server (NTRS)

    Cheong, Deock-Soo; Sanders, William A.

    1990-01-01

    It was indicated that Si3N4 doped with Sc2O3 may exhibit high temperature mechanical properties superior to Si3N4 systems with various other oxide sintered additives. High temperature deformation of samples was studied by characterizing the microstructures before and after deformation. It was found that elements of the additive, such as Sc and O, exist in small amounts at very thin grain boundary layers and most of them stay in secondary phases at triple and multiple grain boundary junctions. These secondary phases are devitrified as crystalline Sc2Si2O7. Deformation of the samples was dominated by cavitational processes rather than movements of dislocations. Thus the excellent deformation resistance of the samples at high temperature can be attributed to the very small thickness of the grain boundary layers and the crystalline secondary phase.

  1. Bilateral and multiple cavitation sounds during upper cervical thrust manipulation

    PubMed Central

    2013-01-01

    Background The popping produced during high-velocity, low-amplitude (HVLA) thrust manipulation is a common sound; however to our knowledge, no study has previously investigated the location of cavitation sounds during manipulation of the upper cervical spine. The primary purpose was to determine which side of the spine cavitates during C1-2 rotatory HVLA thrust manipulation. Secondary aims were to calculate the average number of pops, the duration of upper cervical thrust manipulation, and the duration of a single cavitation. Methods Nineteen asymptomatic participants received two upper cervical thrust manipulations targeting the right and left C1-2 articulation, respectively. Skin mounted microphones were secured bilaterally over the transverse process of C1, and sound wave signals were recorded. Identification of the side, duration, and number of popping sounds were determined by simultaneous analysis of spectrograms with audio feedback using custom software developed in Matlab. Results Bilateral popping sounds were detected in 34 (91.9%) of 37 manipulations while unilateral popping sounds were detected in just 3 (8.1%) manipulations; that is, cavitation was significantly (P < 0.001) more likely to occur bilaterally than unilaterally. Of the 132 total cavitations, 72 occurred ipsilateral and 60 occurred contralateral to the targeted C1-2 articulation. In other words, cavitation was no more likely to occur on the ipsilateral than the contralateral side (P = 0.294). The mean number of pops per C1-2 rotatory HVLA thrust manipulation was 3.57 (95% CI: 3.19, 3.94) and the mean number of pops per subject following both right and left C1-2 thrust manipulations was 6.95 (95% CI: 6.11, 7.79). The mean duration of a single audible pop was 5.66 ms (95% CI: 5.36, 5.96) and the mean duration of a single manipulation was 96.95 ms (95% CI: 57.20, 136.71). Conclusions Cavitation was significantly more likely to occur bilaterally than unilaterally during upper cervical HVLA thrust manipulation. Most subjects produced 3–4 pops during a single rotatory HVLA thrust manipulation targeting the right or left C1-2 articulation; therefore, practitioners of spinal manipulative therapy should expect multiple popping sounds when performing upper cervical thrust manipulation to the atlanto-axial joint. Furthermore, the traditional manual therapy approach of targeting a single ipsilateral or contralateral facet joint in the upper cervical spine may not be realistic. PMID:23320608

  2. Utilization of diagnostic ultrasound and intravenous lipid-encapsulated perfluorocarbons in non-invasive targeted cardiovascular therapeutics.

    PubMed

    Porter, Thomas R; Choudhury, Songita A; Xie, Feng

    2016-01-01

    Diagnostic ultrasound (DUS) pressures have the ability to induce inertial cavitation (IC) of systemically administered microbubbles; this bioeffect has many diagnostic and therapeutic implications in cardiovascular care. Diagnostically, commercially available lipid-encapsulated perfluorocarbons (LEP) can be utilized to improve endocardial and vascular border delineation as well as assess myocardial perfusion. Therapeutically, the liquid jets induced by IC can alter endothelial function and dissolve thrombi within the immediate vicinity of the cavitating microbubbles. The cavitating LEP can also result in the localized release of any bound therapeutic substance at the site of insonation. DUS-induced IC has been tested in pre-clinical studies to determine what effect it has on acute vascular and microvascular thrombosis as well as nitric oxide (NO) release. These pre-clinical studies have consistently shown that DUS-induced IC of LEP is effective in restoring coronary vascular and microvascular flow in acute ST segment elevation myocardial infarction (STEMI), with microvascular flow improving even if upstream large vessel flow has not been achieved. The initial clinical trials examining the efficacy of short pulse duration DUS high mechanical index impulses in patients with STEMI are underway, and preliminary studies have suggested that earlier epicardial vessel recanalization can be achieved prior to arriving in the cardiac catheterization laboratory. DUS high mechanical index impulses have also been effective in pre-clinical studies for targeting DNA delivery that has restored islet cell function in type I diabetes and restored vascular flow in the extremities downstream from a peripheral vascular occlusion. Improvements in this technique will come from three dimensional arrays for therapeutic applications, more automated delivery techniques that can be applied in the field, and use of submicron-sized acoustically activated LEP droplets that may better permeate the clot prior to DUS activation and cavitation. This article will focus on these newer developments for DUS therapeutic applications.

  3. Extracting a Whisper from the DIN: A Bayesian-Inductive Approach to Learning an Anticipatory Model of Cavitation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kercel, S.W.

    1999-11-07

    For several reasons, Bayesian parameter estimation is superior to other methods for inductively learning a model for an anticipatory system. Since it exploits prior knowledge, the analysis begins from a more advantageous starting point than other methods. Also, since "nuisance parameters" can be removed from the Bayesian analysis, the description of the model need not be as complete as is necessary for such methods as matched filtering. In the limit of perfectly random noise and a perfect description of the model, the signal-to-noise ratio improves as the square root of the number of samples in the data. Even with themore » imperfections of real-world data, Bayesian methods approach this ideal limit of performance more closely than other methods. These capabilities provide a strategy for addressing a major unsolved problem in pump operation: the identification of precursors of cavitation. Cavitation causes immediate degradation of pump performance and ultimate destruction of the pump. However, the most efficient point to operate a pump is just below the threshold of cavitation. It might be hoped that a straightforward method to minimize pump cavitation damage would be to simply adjust the operating point until the inception of cavitation is detected and then to slightly readjust the operating point to let the cavitation vanish. However, due to the continuously evolving state of the fluid moving through the pump, the threshold of cavitation tends to wander. What is needed is to anticipate cavitation, and this requires the detection and identification of precursor features that occur just before cavitation starts.« less

  4. Frequency characteristics of liquid hydrogen cavitating flow over a NACA0015 hydrofoil

    NASA Astrophysics Data System (ADS)

    Zhu, Jiakai; Wang, Shunhao; Qiu, Limin; Zhi, Xiaoqin; Zhang, Xiaobin

    2018-03-01

    Large eddy simulation on unsteady cavitating flow of liquid hydrogen over a three-dimensional NACA0015 hydrofoil with the attack angle (α) of 6° are carried out to investigate the dynamic features of cavity with the existence of thermal effects. The numerical model considers the compressibility of both liquid and vapor phase, and is validated by comparing the results with the available experimental data. Special emphasis is put on analyzing the frequency characteristics of cavitation cloud. Strouhal number (St) is plotted against σ/2α (σ is cavitation number), and the water cavitation data reported by Andrt et al. are also used as a reference. It is found that the St number for LH2 cavitation is much smaller than the water, in which the thermal effects are generally not considered, at the same σ/2α value when it is greater than about 2.0, while it returns to the same level as water when σ/2α decreases to below 2.0. The reason is primarily ascribed to the thermal effects, and the detailed explanations are given based on the recognitions that the shedding mechanism of cavitation clouds is predominated by the combined action of the vortex flow and thermal effects. While, when σ/2α decreases to a critical value, the relative effect of the thermal effects on the cavitation dynamics is greatly weakened compared with the mechanism due to the vortex flow, like those in isothermal cavitation flow in traditional fluids. The results provide a deeper understanding of the cryogenic fluid cavitation flow.

  5. Non-human primate skull effects on the cavitation detection threshold of FUS-induced blood-brain barrier opening

    NASA Astrophysics Data System (ADS)

    Wu, Shih-Ying; Tung, Yao-Sheng; Marquet, Fabrice; Chen, Cherry C.; Konofagou, Elisa E.

    2012-11-01

    Microbubble (MB)-assisted focused ultrasound is a promising technique for delivering drugs to the brain by noninvasively and transiently opening the blood-brain barrier (BBB), and monitoring BBB opening using passive cavitation detection (PCD) is critical in detecting its occurrence, extent as well as assessing its mechanism. One of the main obstacles in achieving those objectives in large animals is the transcranial attenuation. To study the effects, the cavitation response through the in-vitro non-human primate (NHP) skull was investigated. In-house manufactured lipid-shelled MB (medium diameter: 4-5 um) were injected into a 4-mm channel of a phantom below a degassed monkey skull. A hydrophone confocally aligned with the FUS transducer served as PCD during sonication (frequency: 0.50 MHz, peak rarefactional pressures: 0.05-0.60 MPa, pulse length: 100 cycles, PRF: 10 Hz, duration: 2 s) for four cases: water without skull, water with skull, MB without skull and MB with skull. A 5.1-MHz linear-array transducer was also used to monitor the MB disruption. The frequency spectra, spectrograms, stable cavitation dose (SCD) and inertial cavitation dose (ICD) were quantified. Results showed that the onset of stable cavitation and inertial cavitation in the experiments occurred at 50 kPa, and was detectable throught the NHP skull since the both the detection thresholds for stable cavitation and inertial cavitation remained unchanged compared to the non-skull case, and the SCD and ICD acquired transcranially may not adequately represent the true extent of stable and inertial cavitation due to the skull attenuation.

  6. Pulse-Inversion Subharmonic Ultrafast Active Cavitation Imaging in Tissue Using Fast Eigenspace-Based Adaptive Beamforming and Cavitation Deconvolution.

    PubMed

    Bai, Chen; Xu, Shanshan; Duan, Junbo; Jing, Bowen; Yang, Miao; Wan, Mingxi

    2017-08-01

    Pulse-inversion subharmonic (PISH) imaging can display information relating to pure cavitation bubbles while excluding that of tissue. Although plane-wave-based ultrafast active cavitation imaging (UACI) can monitor the transient activities of cavitation bubbles, its resolution and cavitation-to-tissue ratio (CTR) are barely satisfactory but can be significantly improved by introducing eigenspace-based (ESB) adaptive beamforming. PISH and UACI are a natural combination for imaging of pure cavitation activity in tissue; however, it raises two problems: 1) the ESB beamforming is hard to implement in real time due to the enormous amount of computation associated with the covariance matrix inversion and eigendecomposition and 2) the narrowband characteristic of the subharmonic filter will incur a drastic degradation in resolution. Thus, in order to jointly address these two problems, we propose a new PISH-UACI method using novel fast ESB (F-ESB) beamforming and cavitation deconvolution for nonlinear signals. This method greatly reduces the computational complexity by using F-ESB beamforming through dimensionality reduction based on principal component analysis, while maintaining the high quality of ESB beamforming. The degraded resolution is recovered using cavitation deconvolution through a modified convolution model and compressive deconvolution. Both simulations and in vitro experiments were performed to verify the effectiveness of the proposed method. Compared with the ESB-based PISH-UACI, the entire computation of our proposed approach was reduced by 99%, while the axial resolution gain and CTR were increased by 3 times and 2 dB, respectively, confirming that satisfactory performance can be obtained for monitoring pure cavitation bubbles in tissue erosion.

  7. Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent.

    PubMed

    Datta, Saurabh; Coussios, Constantin-C; Ammi, Azzdine Y; Mast, T Douglas; de Courten-Myers, Gabrielle M; Holland, Christy K

    2008-09-01

    Ultrasound has been shown previously to act synergistically with a thrombolytic agent, such as recombinant tissue plasminogen activator (rt-PA) to accelerate thrombolysis. In this in vitro study, a commercial contrast agent, Definity, was used to promote and sustain the nucleation of cavitation during pulsed ultrasound exposure at 120 kHz. Ultraharmonic signals, broadband emissions and harmonics of the fundamental were measured acoustically by using a focused hydrophone as a passive cavitation detector and used to quantify the level of cavitation activity. Human whole blood clots suspended in human plasma were exposed to a combination of rt-PA, Definity and ultrasound at a range of ultrasound peak-to-peak pressure amplitudes, which were selected to expose clots to various degrees of cavitation activity. Thrombolytic efficacy was determined by measuring clot mass loss before and after the treatment and correlated with the degree of cavitation activity. The penetration depth of rt-PA and plasminogen was also evaluated in the presence of cavitating microbubbles using a dual-antibody fluorescence imaging technique. The largest mass loss (26.2%) was observed for clots treated with 120-kHz ultrasound (0.32-MPa peak-to-peak pressure amplitude), rt-PA and stable cavitation nucleated by Definity. A significant correlation was observed between mass loss and ultraharmonic signals (r = 0.85, p < 0.0001, n = 24). The largest mean penetration depth of rt-PA (222 microm) and plasminogen (241 microm) was observed in the presence of stable cavitation activity. Stable cavitation activity plays an important role in enhancement of thrombolysis and can be monitored to evaluate the efficacy of thrombolytic treatment.

  8. A Numerical Study of Cavitation Inception in Complex Flow Fields

    DTIC Science & Technology

    2007-12-01

    field in a tip vortex flow of an open propeller to better describe the interaction between the blade wake and the tip vortex (i.e. the roll-up... WAKE INTERACTION ON CAVITATION INCEPTION IN AN OPEN PROPELLER ................15 2.5 NON-SPHERICAL BUBBLE EFFECTS ON CAVITATION INCEPTION [14,15...18 2.6 STUDY OF CAVITATION INCEPTION NOISE [16,17,18

  9. Influence of cavitation bubble growth by rectified diffusion on cavitation-enhanced HIFU

    NASA Astrophysics Data System (ADS)

    Okita, Kohei; Sugiyama, Kazuyasu; Takagi, Shu; Matsumoto, Yoichiro

    2017-11-01

    Cavitation is becoming increasingly important in therapeutic ultrasound applications such as diagnostic, tumor ablation and lithotripsy. Mass transfer through gas-liquid interface due to rectified diffusion is important role in an initial stage of cavitation bubble growth. In the present study, influences of the rectified diffusion on cavitation-enhanced high-intensity focused ultrasound (HIFU) was investigated numerically. Firstly, the mass transfer rate of gas from the surrounding medium to the bubble was examined as function of the initial bubble radius and the driving pressure amplitude. As the result, the pressure required to bubble growth was decreases with increasing the initial bubble radius. Next, the cavitation-enhanced HIFU, which generates cavitation bubbles by high-intensity burst and induces the localized heating owing to cavitation bubble oscillation by low-intensity continuous waves, was reproduced by the present simulation. The heating region obtained by the simulation is agree to the treatment region of an in vitro experiment. Additionally, the simulation result shows that the localized heating is enhanced by the increase of the equilibrium bubble size due to the rectified diffusion. This work was supported by JSPS KAKENHI Grant Numbers JP26420125,JP17K06170.

  10. A New Strategy to Enhance Cavitational Tissue Erosion Using a High-Intensity, Initiating Sequence

    PubMed Central

    Xu, Zhen; Fowlkes, J. Brian; Cain, Charles A.

    2009-01-01

    Our previous studies have shown that pulsed ultrasound can physically remove soft tissue through cavitation. A new strategy to enhance the cavitation-induced erosion is proposed wherein tissue erosion is initiated by a short, high-intensity sequence of pulses and sustained by lower intensity pulses. We investigated effects of the initiating sequence on erosion and cavitation sustained by lower intensity pulses. Multiple three-cycle pulses at a pulse repetition frequency of 20 kHz delivered by a 788-kHz focused transducer were used for tissue erosion. Fixing the initiating sequence at ISPPA of 9000 W/cm2, 16 combinations of different numbers of pulses within the initiating sequence and different sustaining pulse intensities were tested. Results showed: the initiating sequence increases the probability of erosion occurrence and the erosion rate with only slight overall increases in propagated energy; the initiating sequence containing more pulses does not increase the sustained cavitation period; and if extinguished and reinitiated, the sustained cavitation period becomes shorter after each initiation, although the waiting time between adjacent cavitation periods is random. The high-intensity, initiating sequence enhances cavitational tissue erosion and enables erosion at intensities significantly lower than what is required to initiate erosion. PMID:16921893

  11. Influence of the vibro-acoustic sensor position on cavitation detection in a Kaplan turbine

    NASA Astrophysics Data System (ADS)

    Schmidt, H.; Kirschner, O.; Riedelbauch, S.; Necker, J.; Kopf, E.; Rieg, M.; Arantes, G.; Wessiak, M.; Mayrhuber, J.

    2014-03-01

    Hydraulic turbines can be operated close to the limits of the operating range to meet the demand of the grid. When operated close to the limits, the risk increases that cavitation phenomena may occur at the runner and / or at the guide vanes of the turbine. Cavitation in a hydraulic turbine can cause material erosion on the runner and other turbine parts and reduce the durability of the machine leading to required outage time and related repair costs. Therefore it is important to get reliable information about the appearance of cavitation during prototype operation. In this experimental investigation the high frequency acoustic emissions and vibrations were measured at 20 operating points with different cavitation behaviour at different positions in a large prototype Kaplan turbine. The main goal was a comparison of the measured signals at different sensor positions to identify the sensitivity of the location for cavitation detection. The measured signals were analysed statistically and specific values were derived. Based on the measured signals, it is possible to confirm the cavitation limit of the examined turbine. The result of the investigation shows that the position of the sensors has a significant influence on the detection of cavitation.

  12. Effects of physical properties on thermo-fluids cavitating flows

    NASA Astrophysics Data System (ADS)

    Chen, T. R.; Wang, G. Y.; Huang, B.; Li, D. Q.; Ma, X. J.; Li, X. L.

    2015-12-01

    The aims of this paper are to study the thermo-fluid cavitating flows and to evaluate the effects of physical properties on cavitation behaviours. The Favre-averaged Navier-Stokes equations with the energy equation are applied to numerically investigate the liquid nitrogen cavitating flows around a NASA hydrofoil. Meanwhile, the thermodynamic parameter Σ is used to assess the thermodynamic effects on cavitating flows. The results indicate that the thermodynamic effects on the thermo-fluid cavitating flows significantly affect the cavitation behaviours, including pressure and temperature distribution, the variation of physical properties, and cavity structures. The thermodynamic effects can be evaluated by physical properties under the same free-stream conditions. The global sensitivity analysis of liquid nitrogen suggests that ρv, Cl and L significantly influence temperature drop and cavity structure in the existing numerical framework, while pv plays the dominant role when these properties vary with temperature. The liquid viscosity μl slightly affects the flow structure via changing the Reynolds number Re equivalently, however, it hardly affects the temperature distribution.

  13. Biomedical device prototype based on small scale hydrodynamic cavitation

    NASA Astrophysics Data System (ADS)

    Ghorbani, Morteza; Sozer, Canberk; Alcan, Gokhan; Unel, Mustafa; Ekici, Sinan; Uvet, Huseyin; Koşar, Ali

    2018-03-01

    This study presents a biomedical device prototype based on small scale hydrodynamic cavitation. The application of small scale hydrodynamic cavitation and its integration to a biomedical device prototype is offered as an important alternative to other techniques, such as ultrasound therapy, and thus constitutes a local, cheap, and energy-efficient solution, for urinary stone therapy and abnormal tissue ablation (e.g., benign prostate hyperplasia (BPH)). The destructive nature of bubbly, cavitating, flows was exploited, and the potential of the prototype was assessed and characterized. Bubbles generated in a small flow restrictive element (micro-orifice) based on hydrodynamic cavitation were utilized for this purpose. The small bubbly, cavitating, flow generator (micro-orifice) was fitted to a small flexible probe, which was actuated with a micromanipulator using fine control. This probe also houses an imaging device for visualization so that the emerging cavitating flow could be locally targeted to the desired spot. In this study, the feasibility of this alternative treatment method and its integration to a device prototype were successfully accomplished.

  14. URANS simulations of the tip-leakage cavitating flow with verification and validation procedures

    NASA Astrophysics Data System (ADS)

    Cheng, Huai-yu; Long, Xin-ping; Liang, Yun-zhi; Long, Yun; Ji, Bin

    2018-04-01

    In the present paper, the Vortex Identified Zwart-Gerber-Belamri (VIZGB) cavitation model coupled with the SST-CC turbulence model is used to investigate the unsteady tip-leakage cavitating flow induced by a NACA0009 hydrofoil. A qualitative comparison between the numerical and experimental results is made. In order to quantitatively evaluate the reliability of the numerical data, the verification and validation (V&V) procedures are used in the present paper. Errors of numerical results are estimated with seven error estimators based on the Richardson extrapolation method. It is shown that though a strict validation cannot be achieved, a reasonable prediction of the gross characteristics of the tip-leakage cavitating flow can be obtained. Based on the numerical results, the influence of the cavitation on the tip-leakage vortex (TLV) is discussed, which indicates that the cavitation accelerates the fusion of the TLV and the tip-separation vortex (TSV). Moreover, the trajectory of the TLV, when the cavitation occurs, is close to the side wall.

  15. Cavitation erosion in blocked flow with a ducted ice-class propeller

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Doucet, J.M.; Bose, N.; Walker, D.

    1996-12-31

    Ships that operate in ice often encounter momentary increased propeller cavitation because ice pieces block the flow into the propeller. For ducted propellers, this additional cavitation is more significant than it is for open propellers; ice pieces may become lodged against and within the duct and subject the propeller to longer periods of increased cavitation due to the blocked flow. Associated with this blocked flow is the possibility of cavitation erosion on the propeller. An erosion study, using paint films, was conducted in a cavitation tunnel with a model propeller of the type fitted to the Canadian Marine Drilling Ltd.more » vessel MV Robert LeMeur. A simulated ice blockage was installed ahead of the propeller model and within the duct. Tests were carried out over a range of advance coefficients for various test conditions. The resulting types of cavitation were documented, the erosion patterns were photographed and comparisons between each test were made.« less

  16. Spectral Analysis of Pressure, Noise and Vibration Velocity Measurement in Cavitation

    NASA Astrophysics Data System (ADS)

    Jablonská, Jana; Mahdal, Miroslav; Kozubková, Milada

    2017-12-01

    The article deals with experimental investigation of water cavitation in the convergent-divergent nozzle of rectangular cross-section. In practice, a quick and simple determination of cavitation is essential, especially if it is basic cavitation or cavitation generated additionally by the air being sucked. Air influences the formation, development and size of the cavity area in hydraulic elements. Removal or reduction of the cavity area is possible by structural changes of the element. In case of the cavitation with the suction air, it is necessary to find the source of the air and seal it. The pressure gradient, the flow, the oxygen content in the tank, and hence the air dissolved in the water, the air flow rate, the noise intensity and the vibration velocity on the nozzle wall were measured on laboratory equipment. From the selected measurements the frequency spectrum of the variation of the water flow of the cavity with cavitation without air saturation and with air saturation was compared and evaluated.

  17. Large eddy simulation of turbulent cavitating flows

    NASA Astrophysics Data System (ADS)

    Gnanaskandan, A.; Mahesh, K.

    2015-12-01

    Large Eddy Simulation is employed to study two turbulent cavitating flows: over a cylinder and a wedge. A homogeneous mixture model is used to treat the mixture of water and water vapor as a compressible fluid. The governing equations are solved using a novel predictor- corrector method. The subgrid terms are modeled using the Dynamic Smagorinsky model. Cavitating flow over a cylinder at Reynolds number (Re) = 3900 and cavitation number (σ) = 1.0 is simulated and the wake characteristics are compared to the single phase results at the same Reynolds number. It is observed that cavitation suppresses turbulence in the near wake and delays three dimensional breakdown of the vortices. Next, cavitating flow over a wedge at Re = 200, 000 and σ = 2.0 is presented. The mean void fraction profiles obtained are compared to experiment and good agreement is obtained. Cavity auto-oscillation is observed, where the sheet cavity breaks up into a cloud cavity periodically. The results suggest LES as an attractive approach for predicting turbulent cavitating flows.

  18. Cavitation Bubble Streaming in Ultrasonic-Standing-Wave Field

    NASA Astrophysics Data System (ADS)

    Nomura, Shinfuku; Mukasa, Shinobu; Kuroiwa, Masaya; Okada, Yasuyuki; Murakami, Koichi

    2005-05-01

    The mechanism of cavitation bubble streaming by ultrasonic vibration in a water tank was experimentally investigated. A standard ultrasonic cleaner unit with a resonant frequency of 40 kHz was used as an ultrasonic generator. The behavior of the streaming was visualized by the schlieren method and sonochemical luminescence, and the velocity of the streaming was measured by laser Doppler velocity measurement equipment (LDV). The cavitation bubble streaming has two structures. A cavitation cloud, which consists of many cavitation bubbles, is shaped like a facing pair of bowls with a diameter of approximately 1/3 the wavelength of the standing wave, and moves inside the standing-wave field with a velocity of 30 to 60 mm/s. The cavitation bubbles move intensely in the cloud with a velocity of 5 m/s at an ultrasonic output power of 75 W. The streaming is completely different from conventional acoustic streaming. Also the cavitation bubble is generated neither at the pressure node nor at the antinode.

  19. Large-eddy simulation of turbulent cavitating flow in a micro channel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Egerer, Christian P., E-mail: christian.egerer@aer.mw.tum.de; Hickel, Stefan; Schmidt, Steffen J.

    2014-08-15

    Large-eddy simulations (LES) of cavitating flow of a Diesel-fuel-like fluid in a generic throttle geometry are presented. Two-phase regions are modeled by a parameter-free thermodynamic equilibrium mixture model, and compressibility of the liquid and the liquid-vapor mixture is taken into account. The Adaptive Local Deconvolution Method (ALDM), adapted for cavitating flows, is employed for discretizing the convective terms of the Navier-Stokes equations for the homogeneous mixture. ALDM is a finite-volume-based implicit LES approach that merges physically motivated turbulence modeling and numerical discretization. Validation of the numerical method is performed for a cavitating turbulent mixing layer. Comparisons with experimental data ofmore » the throttle flow at two different operating conditions are presented. The LES with the employed cavitation modeling predicts relevant flow and cavitation features accurately within the uncertainty range of the experiment. The turbulence structure of the flow is further analyzed with an emphasis on the interaction between cavitation and coherent motion, and on the statistically averaged-flow evolution.« less

  20. Computing Thermal Effects of Cavitation in Cryogenic Liquids

    NASA Technical Reports Server (NTRS)

    Hosangadi, Ashvin; Ahuja, Vineet; Dash, Sanford M.

    2005-01-01

    A computer program implements a numerical model of thermal effects of cavitation in cryogenic fluids. The model and program were developed for use in designing and predicting the performances of turbopumps for cryogenic fluids. Prior numerical models used for this purpose do not account for either the variability of properties of cryogenic fluids or the thermal effects (especially, evaporative cooling) involved in cavitation. It is important to account for both because in a cryogenic fluid, the thermal effects of cavitation are substantial, and the cavitation characteristics are altered by coupling between the variable fluid properties and the phase changes involved in cavitation. The present model accounts for both thermal effects and variability of properties by incorporating a generalized representation of the properties of cryogenic fluids into a generalized compressible-fluid formulation for a cavitating pump. The model has been extensively validated for liquid nitrogen and liquid hydrogen. Using the available data on the properties of these fluids, the model has been shown to predict accurate temperature-depression values.

  1. Cavitation behavior observed in three monoleaflet mechanical heart valves under accelerated testing conditions.

    PubMed

    Lo, Chi-Wen; Liu, Jia-Shing; Li, Chi-Pei; Lu, Po-Chien; Hwang, Ned H

    2008-01-01

    Accelerated testing provides a substantial amount of data on mechanical heart valve durability in a short period of time, but such conditions may not accurately reflect in vivo performance. Cavitation, which occurs during mechanical heart valve closure when local flow field pressure decreases below vapor pressure, is thought to play a role in valve damage under accelerated conditions. The underlying flow dynamics and mechanisms behind cavitation bubble formation are poorly understood. Under physiologic conditions, random perivalvular cavitation is difficult to capture. We applied accelerated testing at a pulse rate of 600 bpm and transvalvular pressure of 120 mm Hg, with synchronized videographs and high-frequency pressure measurements, to study cavitation of the Medtronic Hall Standard (MHS), Medtronic Hall D-16 (MHD), and Omni Carbon (OC) valves. Results showed cavitation bubbles between 340 and 360 micros after leaflet/housing impact of the MHS, MHD, and OC valves, intensified by significant leaflet rebound. Squeeze flow, Venturi, and water hammer effects each contributed to cavitation, depending on valve design.

  2. Selective detection of cavitation bubbles by triplet pulse sequence in high-intensity focused ultrasound treatment

    NASA Astrophysics Data System (ADS)

    Iwasaki, Ryosuke; Nagaoka, Ryo; Yoshizawa, Shin; Umemura, Shin-ichiro

    2018-07-01

    Acoustic cavitation bubbles are known to enhance the heating effect in high-intensity focused ultrasound (HIFU) treatment. The detection of cavitation bubbles with high sensitivity and selectivity is required to predict the therapeutic and side effects of cavitation, and ensure the efficacy and safety of the treatment. A pulse inversion (PI) technique has been widely used for imaging microbubbles through enhancing the second-harmonic component of echo signals. However, it has difficulty in separating the nonlinear response of microbubbles from that due to nonlinear propagation. In this study, a triplet pulse (3P) method was investigated to specifically image cavitation bubbles by extracting the 1.5th fractional harmonic component. The proposed 3P method depicted cavitation bubbles with a contrast ratio significantly higher than those in conventional imaging methods with and without PI. The results suggest that the 3P method is effective for specifically detecting microbubbles in cavitation-enhanced HIFU treatment.

  3. Localization of incipient tip vortex cavitation using ray based matched field inversion method

    NASA Astrophysics Data System (ADS)

    Kim, Dongho; Seong, Woojae; Choo, Youngmin; Lee, Jeunghoon

    2015-10-01

    Cavitation of marine propeller is one of the main contributing factors of broadband radiated ship noise. In this research, an algorithm for the source localization of incipient vortex cavitation is suggested. Incipient cavitation is modeled as monopole type source and matched-field inversion method is applied to find the source position by comparing the spatial correlation between measured and replicated pressure fields at the receiver array. The accuracy of source localization is improved by broadband matched-field inversion technique that enhances correlation by incoherently averaging correlations of individual frequencies. Suggested localization algorithm is verified through known virtual source and model test conducted in Samsung ship model basin cavitation tunnel. It is found that suggested localization algorithm enables efficient localization of incipient tip vortex cavitation using a few pressure data measured on the outer hull above the propeller and practically applicable to the typically performed model scale experiment in a cavitation tunnel at the early design stage.

  4. Observation of pressure variation in the cavitation region of submerged journal bearings

    NASA Technical Reports Server (NTRS)

    Etsion, I.; Ludwig, L. P.

    1981-01-01

    Visual observations and pressure measurements in the cavitation zone of a submerged journal bearing are described. Tests are run at speeds of 1840 and 3000 rpm, and at each speed, four different levels of the ambient supply pressure are applied, ranging from 13.6 KPa to 54.4 KPa. A strong reverse flow is detected inside the cavitation area adjacent to its downstream end, and significant pressure variations on the order of 50 KPa are found inside the cavitation region at the downstream portion of its circumferential extent. Results indicate that the assumption of a constant cavitation pressure is incorrect in the case of enclosed cavitations, and it is postulated that oil which is saturated with air under atmospheric pressure becomes oversaturated in the subcavity pressure loop.

  5. On fiber optic probe hydrophone measurements in a cavitating liquid.

    PubMed

    Zijlstra, Aaldert; Ohl, Claus Dieter

    2008-01-01

    The measurement of high-pressure signals is often hampered by cavitation activity. The usage of a fiber optic probe hydrophone possesses advantages over other hydrophones, yet when measuring in a cavitating liquid large variations in the signal amplitude are found; in particular when the pressure signal recovers back to positive values. With shadowgraphy the wave propagation and cavity dynamics are imaged and the important contributions of secondary shock waves emitted from collapsing cavitation bubbles are revealed. Interestingly, just adding a small amount of acidic acid reduces the cavitation activity to a large extent. With this treatment an altered primary pressure profile which does not force the cavitation bubbles close to fiber tip into collapse has been found. Thereby, the shot-to-shot variations are greatly reduced.

  6. Integrated ultrasound and magnetic resonance imaging for simultaneous temperature and cavitation monitoring during focused ultrasound therapies

    PubMed Central

    Arvanitis, Costas D.; McDannold, Nathan

    2013-01-01

    Purpose: Ultrasound can be used to noninvasively produce different bioeffects via viscous heating, acoustic cavitation, or their combination, and these effects can be exploited to develop a wide range of therapies for cancer and other disorders. In order to accurately localize and control these different effects, imaging methods are desired that can map both temperature changes and cavitation activity. To address these needs, the authors integrated an ultrasound imaging array into an MRI-guided focused ultrasound (MRgFUS) system to simultaneously visualize thermal and mechanical effects via passive acoustic mapping (PAM) and MR temperature imaging (MRTI), respectively. Methods: The system was tested with an MRgFUS system developed for transcranial sonication for brain tumor ablation in experiments with a tissue mimicking phantom and a phantom-filled ex vivo macaque skull. In experiments on cavitation-enhanced heating, 10 s continuous wave sonications were applied at increasing power levels (30–110 W) until broadband acoustic emissions (a signature for inertial cavitation) were evident. The presence or lack of signal in the PAM, as well as its magnitude and location, were compared to the focal heating in the MRTI. Additional experiments compared PAM with standard B-mode ultrasound imaging and tested the feasibility of the system to map cavitation activity produced during low-power (5 W) burst sonications in a channel filled with a microbubble ultrasound contrast agent. Results: When inertial cavitation was evident, localized activity was present in PAM and a marked increase in heating was observed in MRTI. The location of the cavitation activity and heating agreed on average after registration of the two imaging modalities; the distance between the maximum cavitation activity and focal heating was −3.4 ± 2.1 mm and −0.1 ± 3.3 mm in the axial and transverse ultrasound array directions, respectively. Distortions and other MRI issues introduced small uncertainties in the PAM/MRTI registration. Although there was substantial variation, a nonlinear relationship between the average intensity of the cavitation maps, which was relatively constant during sonication, and the peak temperature rise was evident. A fit to the data to an exponential had a correlation coefficient (R2) of 0.62. The system was also found to be capable of visualizing cavitation activity with B-mode imaging and of passively mapping cavitation activity transcranially during cavitation-enhanced heating and during low-power sonication with an ultrasound contrast agent. Conclusions: The authors have demonstrated the feasibility of integrating an ultrasound imaging array into an MRgFUS system to simultaneously map localized cavitation activity and temperature. The authors anticipate that this integrated approach can be utilized to develop controllers for cavitation-enhanced ablation and facilitate the optimization and development of this and other ultrasound therapies. The integrated system may also provide a useful tool to study the bioeffects of acoustic cavitation. PMID:24320468

  7. Integrated ultrasound and magnetic resonance imaging for simultaneous temperature and cavitation monitoring during focused ultrasound therapies.

    PubMed

    Arvanitis, Costas D; McDannold, Nathan

    2013-11-01

    Ultrasound can be used to noninvasively produce different bioeffects via viscous heating, acoustic cavitation, or their combination, and these effects can be exploited to develop a wide range of therapies for cancer and other disorders. In order to accurately localize and control these different effects, imaging methods are desired that can map both temperature changes and cavitation activity. To address these needs, the authors integrated an ultrasound imaging array into an MRI-guided focused ultrasound (MRgFUS) system to simultaneously visualize thermal and mechanical effects via passive acoustic mapping (PAM) and MR temperature imaging (MRTI), respectively. The system was tested with an MRgFUS system developed for transcranial sonication for brain tumor ablation in experiments with a tissue mimicking phantom and a phantom-filled ex vivo macaque skull. In experiments on cavitation-enhanced heating, 10 s continuous wave sonications were applied at increasing power levels (30-110 W) until broadband acoustic emissions (a signature for inertial cavitation) were evident. The presence or lack of signal in the PAM, as well as its magnitude and location, were compared to the focal heating in the MRTI. Additional experiments compared PAM with standard B-mode ultrasound imaging and tested the feasibility of the system to map cavitation activity produced during low-power (5 W) burst sonications in a channel filled with a microbubble ultrasound contrast agent. When inertial cavitation was evident, localized activity was present in PAM and a marked increase in heating was observed in MRTI. The location of the cavitation activity and heating agreed on average after registration of the two imaging modalities; the distance between the maximum cavitation activity and focal heating was -3.4 ± 2.1 mm and -0.1 ± 3.3 mm in the axial and transverse ultrasound array directions, respectively. Distortions and other MRI issues introduced small uncertainties in the PAM∕MRTI registration. Although there was substantial variation, a nonlinear relationship between the average intensity of the cavitation maps, which was relatively constant during sonication, and the peak temperature rise was evident. A fit to the data to an exponential had a correlation coefficient (R(2)) of 0.62. The system was also found to be capable of visualizing cavitation activity with B-mode imaging and of passively mapping cavitation activity transcranially during cavitation-enhanced heating and during low-power sonication with an ultrasound contrast agent. The authors have demonstrated the feasibility of integrating an ultrasound imaging array into an MRgFUS system to simultaneously map localized cavitation activity and temperature. The authors anticipate that this integrated approach can be utilized to develop controllers for cavitation-enhanced ablation and facilitate the optimization and development of this and other ultrasound therapies. The integrated system may also provide a useful tool to study the bioeffects of acoustic cavitation.

  8. Numerical and experimental study of a hydrodynamic cavitation tube

    NASA Astrophysics Data System (ADS)

    Hu, H.; Finch, J. A.; Zhou, Z.; Xu, Z.

    1998-08-01

    A numerical analysis of hydrodynamics in a cavitation tube used for activating fine particle flotation is described. Using numerical procedures developed for solving the turbulent k-ɛ model with boundary fitted coordinates, the stream function, vorticity, velocity, and pressure distributions in a cavitation tube were calculated. The calculated pressure distribution was found to be in excellent agreement with experimental results. The requirement of a pressure drop below approximately 10 m water for cavitation to occur was observed experimentally and confirmed by the model. The use of the numerical procedures for cavitation tube design is discussed briefly.

  9. Cavitation induced by high speed impact of a solid surface on a liquid jet

    NASA Astrophysics Data System (ADS)

    Farhat, Mohamed; Tinguely, Marc; Rouvinez, Mathieu

    2009-11-01

    A solid surface may suffer from severe erosion if it impacts a liquid jet at high speed. The physics behind the erosion process remains unclear. In the present study, we have investigated the impact of a gun bullet on a laminar water jet with the help of a high speed camera. The bullet has a flat front and 11 mm diameter, which is half of jet diameter. The impact speed was varied between 200 and 500 ms-1. Immediately after the impact, a systematic shock wave and high speed jetting were observed. As the compression waves reflect on the jet boundary, a spectacular number of vapour cavities are generated within the jet. Depending on the bullet velocity, these cavities may grow and collapse violently on the bullet surface with a risk of cavitation erosion. We strongly believe that this transient cavitation is the main cause of erosion observed in many industrial applications such as Pelton turbines.

  10. The Role of Acoustic Cavitation in Ultrasound-triggered Drug Release from Echogenic Liposomes

    NASA Astrophysics Data System (ADS)

    Kopechek, Jonathan A.

    Cardiovascular disease (CVD) is the leading cause of death in the United States and globally. CVD-related mortality, including coronary heart disease, heart failure, or stroke, generally occurs due to atherosclerosis, a condition in which plaques build up within arterial walls, potentially causing blockage or rupture. Targeted therapies are needed to achieve more effective treatments. Echogenic liposomes (ELIP), which consist of a lipid membrane surrounding an aqueous core, have been developed to encapsulate a therapeutic agent and/or gas bubbles for targeted delivery and ultrasound image enhancement. Under certain conditions ultrasound can cause nonlinear bubble growth and collapse, known as "cavitation." Cavitation activity has been associated with enhanced drug delivery across cellular membranes. However, the mechanisms of ultrasound-mediated drug release from ELIP have not been previously investigated. Thus, the objective of this dissertation is to elucidate the role of acoustic cavitation in ultrasound-mediated drug release from ELIP. To determine the acoustic and physical properties of ELIP, the frequency-dependent attenuation and backscatter coefficients were measured between 3 and 30 MHz. The results were compared to a theoretical model by measuring the ELIP size distribution in order to determine properties of the lipid membrane. It was found that ELIP have a broad size distribution and can provide enhanced ultrasound image contrast across a broad range of clinically-relevant frequencies. Calcein, a hydrophilic fluorescent dye, and papaverine, a lipophilic vasodilator, were separately encapsulated in ELIP and exposed to color Doppler ultrasound pulses from a clinical diagnostic ultrasound scanner in a flow system. Spectrophotometric techniques (fluorescence and absorbance measurements) were used to detect calcein or papaverine release. As a positive control, Triton X-100 (a non-ionic detergent) was added to ELIP samples not exposed to ultrasound in order to release encapsulated agents completely. Also, sham samples without Triton X-100 or ultrasound exposure were used as negative controls. Color Doppler ultrasound did not release encapsulated calcein or papaverine from ELIP even though there was a complete loss of echogenicity. In subsequent experiments, calcein and rosiglitazone, a hydrophobic anti-diabetic drug, were separately encapsulated in ELIP and exposed to pulsed Doppler ultrasound in a flow system while monitoring cavitation. Samples were exposed to ultrasound pressures above and below cavitation thresholds. In addition, Triton X-100 was used for positive control samples and sham samples were also tested without ultrasound exposure. Adding Triton X-100 resulted in complete release of encapsulated calcein or rosiglitzone. However, Doppler ultrasound exposure did not induce calcein or rosiglitazone release from ELIP in the flow system even when there was persistent cavitation activity and a loss of echogenicity. The results of this dissertation indicate that cavitation of encapsulated bubbles in ELIP solutions is not sufficient to induce drug release. It is possible that ultrasoundmediated thermal processes may have a stronger effect on ELIP permeability than cavitation activity. Perhaps ultrasound-triggered drug release will be possible by improving the ELIP formulation or encapsulating a different gas instead of air. However, cavitation is not a reliable indicator of ultrasound-mediated drug release with the ELIP formulations used in this dissertation.

  11. A critical review on textile wastewater treatments: Possible approaches.

    PubMed

    Holkar, Chandrakant R; Jadhav, Ananda J; Pinjari, Dipak V; Mahamuni, Naresh M; Pandit, Aniruddha B

    2016-11-01

    Waste water is a major environmental impediment for the growth of the textile industry besides the other minor issues like solid waste and resource waste management. Textile industry uses many kinds of synthetic dyes and discharge large amounts of highly colored wastewater as the uptake of these dyes by fabrics is very poor. This highly colored textile wastewater severely affects photosynthetic function in plant. It also has an impact on aquatic life due to low light penetration and oxygen consumption. It may also be lethal to certain forms of marine life due to the occurrence of component metals and chlorine present in the synthetic dyes. So, this textile wastewater must be treated before their discharge. In this article, different treatment methods to treat the textile wastewater have been presented along with cost per unit volume of treated water. Treatment methods discussed in this paper involve oxidation methods (cavitation, photocatalytic oxidation, ozone, H2O2, fentons process), physical methods (adsorption and filtration), biological methods (fungi, algae, bacteria, microbial fuel cell). This review article will also recommend the possible remedial measures to treat different types of effluent generated from each textile operation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Occurrence of hydrodynamic cavitation.

    PubMed

    Nosov, V R; Gómez-Mancilla, J C; Meda-Campaña, J A

    2011-01-01

    In this paper, the conditions under which cavitation (or liquid film rupture) can or cannot occur in thin layers of moving liquid are derived for three typical cases. At the same time, expressions depending on geometrical and movement parameters, where cavitation might start, are given. The results are obtained using simple engineering terms, which can be used in cases whether it is necessary to avoid cavitation or to induce it.

  13. Role of H2O2 in the fluctuating patterns of COD (chemical oxygen demand) during the treatment of palm oil mill effluent (POME) using pilot scale triple frequency ultrasound cavitation reactor.

    PubMed

    Manickam, Sivakumar; Abidin, Norhaida binti Zainal; Parthasarathy, Shridharan; Alzorqi, Ibrahim; Ng, Ern Huay; Tiong, Timm Joyce; Gomes, Rachel L; Ali, Asgar

    2014-07-01

    Palm oil mill effluent (POME) is a highly contaminating wastewater due to its high chemical oxygen demand (COD) and biochemical oxygen demand (BOD). Conventional treatment methods require longer residence time (10-15 days) and higher operating cost. Owing to this, finding a suitable and efficient method for the treatment of POME is crucial. In this investigation, ultrasound cavitation technology has been used as an alternative technique to treat POME. Cavitation is the phenomenon of formation, growth and collapse of bubbles in a liquid. The end process of collapse leads to intense conditions of temperature and pressure and shock waves which assist various physical and chemical transformations. Two different ultrasound systems i.e. ultrasonic bath (37 kHz) and a hexagonal triple frequency ultrasonic reactor (28, 40 and 70 kHz) of 15 L have been used. The results showed a fluctuating COD pattern (in between 45,000 and 60,000 mg/L) while using ultrasound bath alone, whereas a non-fluctuating COD pattern with a final COD of 27,000 mg/L was achieved when hydrogen peroxide was introduced. Similarly for the triple frequency ultrasound reactor, coupling all the three frequencies resulted into a final COD of 41,300 mg/L compared to any other individual or combination of two frequencies. With the possibility of larger and continuous ultrasonic cavitational reactors, it is believed that this could be a promising and a fruitful green process engineering technique for the treatment of POME. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Acoustic Cavitation-Based Monitoring of the Reversibility and Permeability of Ultrasound-Induced Blood-Brain Barrier Opening

    PubMed Central

    Sun, Tao; Samiotaki, Gesthimani; Wang, Shutao; Acosta, Camilo; Chen, Cherry C.; Konofagou, Elisa E.

    2015-01-01

    Cavitation events seeded by microbubbles have been previously reported to be associated with MR- or fluorescent-contrast enhancement after focused ultrasound (FUS)-induced blood-brain barrier (BBB) opening. However, it is still unknown whether bubble activity can be correlated with the reversibility (the duration of opening and the likelihood of safe reinstatement) and the permeability of opened BBB, which is critical for the clinical translation of using passive cavitation detection to monitor, predict and control the opening. In this study, the dependence of acoustic cavitation on the BBB opening duration, permeability coefficient and histological damage occurrence were thus investigated. Transcranial pulsed FUS at 1.5 MHz in the presence of systemically circulating microbubbles was applied in the mouse hippocampi (n = 60). The stable and inertial cavitation activities were monitored during sonication. Contrast-enhanced MRI was performed immediately after sonication and every 24 h up to 6 days thereafter, to assess BBB opening, brain tissue permeability and potential edema. Histological evaluations were used to assess the occurrence of neurovascular damages. It was found that stable cavitation was well correlated with: 1) the duration of the BBB opening (r2 = 0.77); 2) the permeability of the opened BBB (r2 = 0.82); 3) the likelihood of safe opening (P < 0.05, safe opening compared to cases of damage; P < 0.0001, no opening compared to safe opening). The inertial cavitation dose was correlated with the resulting BBB permeability (r2 = 0.72). Stable cavitation was found to be more reliable than inertial cavitation at assessing the BBB opening within the pressure range used in this study. This study demonstrates that the stable cavitation response during BBB opening holds promise for predicting and controlling the restoration and pharmacokinetics of FUS-opened BBB. The stable cavitation response therefore showed great promise in predicting the BBB opening duration, enabling thus control of opening according to the drug circulation time. In addition, avoiding adverse effects in the brain and assessing the pharmacokinetics of the compounds delivered can also be achieved by monitoring and controlling the stable cavitation emissions. PMID:26562661

  15. Multi-focal HIFU reduces cavitation in mild-hyperthermia.

    PubMed

    Chaplin, Vandiver; Caskey, Charles F

    2017-01-01

    Mild-hyperthermia therapy (40-45 °C) with high-intensity focused ultrasound (HIFU) is a technique being considered in a number of different treatments such as thermally activated drug delivery, immune-stimulation, and as a chemotherapy adjuvant. Mechanical damage and loss of cell viability associated with HIFU-induced acoustic cavitation may pose a risk during these treatments or may hinder their success. Here we present a method that achieves mild heating and reduces cavitation by using a multi-focused HIFU beam. We quantify cavitation level and temperature rise in multi-focal sonications and compare it to single-focus sonications at the transducer geometric focus. Continuous wave sonications were performed with the Sonalleve V2 transducer in gel phantoms and pork at 5, 10, 20, 40, 60, 80 acoustic watts for 30 s. Cavitation activity was measured with two ultrasound (US) imaging probes, both by computing the raw channel variance and using passive acoustic mapping (PAM). Temperature rise was measured with MR thermometry at 3 T. Cavitation and heating were compared for single- and multi-focal sonication geometries. Multi-focal sonications used four points equally spaced on a ring of either 4 mm or 8 mm diameter. Single-focus sonications were not steered. Multi-focal sonication generated distinct foci that were visible in MRI thermal maps in both phantoms and pork, and visible in PAM images in phantoms only. Cavitation activity (measured by channel variance) and mean PAM image value were highly correlated (r > 0.9). In phantoms, cavitation exponentially decreased over the 30-second sonication, consistent with depletion of cavitation nuclei. In pork, sporadic spikes signaling cavitation were observed with single focusing only. In both materials, the widest beam reduced average and peak cavitation level by a factor of two or more at each power tested when compared to a single focus. The widest beam reduced peak temperature by at least 10 °C at powers above 5 W, and created heating that was more spatially diffuse than single focus, resulting in more voxels in the mild heating (3-8 °C) range. Multi-focal HIFU can be used to achieve mild temperature elevation and reduce cavitation activity.

  16. Effect of acoustic parameters on the cavitation behavior of SonoVue microbubbles induced by pulsed ultrasound.

    PubMed

    Lin, Yutong; Lin, Lizhou; Cheng, Mouwen; Jin, Lifang; Du, Lianfang; Han, Tao; Xu, Lin; Yu, Alfred C H; Qin, Peng

    2017-03-01

    SonoVue microbubbles could serve as artificial nuclei for ultrasound-triggered stable and inertial cavitation, resulting in beneficial biological effects for future therapeutic applications. To optimize and control the use of the cavitation of SonoVue bubbles in therapy while ensuring safety, it is important to comprehensively understand the relationship between the acoustic parameters and the cavitation behavior of the SonoVue bubbles. An agarose-gel tissue phantom was fabricated to hold the SonoVue bubble suspension. 1-MHz transmitting transducer calibrated by a hydrophone was used to trigger the cavitation of SonoVue bubbles under different ultrasonic parameters (i.e., peak rarefactional pressure (PRP), pulse repetition frequency (PRF), and pulse duration (PD)). Another 7.5-MHz focused transducer was employed to passively receive acoustic signals from the exposed bubbles. The ultraharmonics and broadband intensities in the acoustic emission spectra were measured to quantify the extent of stable and inertial cavitation of SonoVue bubbles, respectively. We found that the onset of both stable and inertial cavitation exhibited a strong dependence on the PRP and PD and a relatively weak dependence on the PRF. Approximate 0.25MPa PRP with more than 20μs PD was considered to be necessary for ultraharmonics emission of SonoVue bubbles, and obvious broadband signals started to appear when the PRP exceeded 0.40MPa. Moreover, the doses of stable and inertial cavitation varied with the PRP. The stable cavitation dose initially increased with increasing PRP, and then decreased rapidly after 0.5MPa. By contrast, the inertial cavitation dose continuously increased with increasing PRP. Finally, the doses of both stable and inertial cavitation were positively correlated with PRF and PD. These results could provide instructive information for optimizing future therapeutic applications of SonoVue bubbles. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. Trans-Stent B-Mode Ultrasound and Passive Cavitation Imaging.

    PubMed

    Haworth, Kevin J; Raymond, Jason L; Radhakrishnan, Kirthi; Moody, Melanie R; Huang, Shao-Ling; Peng, Tao; Shekhar, Himanshu; Klegerman, Melvin E; Kim, Hyunggun; McPherson, David D; Holland, Christy K

    2016-02-01

    Angioplasty and stenting of a stenosed artery enable acute restoration of blood flow. However, restenosis or a lack of re-endothelization can subsequently occur depending on the stent type. Cavitation-mediated drug delivery is a potential therapy for these conditions, but requires that particular types of cavitation be induced by ultrasound insonation. Because of the heterogeneity of tissue and stochastic nature of cavitation, feedback mechanisms are needed to determine whether the sustained bubble activity is induced. The objective of this study was to determine the feasibility of passive cavitation imaging through a metal stent in a flow phantom and an animal model. In this study, an endovascular stent was deployed in a flow phantom and in porcine femoral arteries. Fluorophore-labeled echogenic liposomes, a theragnostic ultrasound contrast agent, were injected proximal to the stent. Cavitation images were obtained by passively recording and beamforming the acoustic emissions from echogenic liposomes insonified with a low-frequency (500 kHz) transducer. In vitro experiments revealed that the signal-to-noise ratio for detecting stable cavitation activity through the stent was greater than 8 dB. The stent did not significantly reduce the signal-to-noise ratio. Trans-stent cavitation activity was also detected in vivo via passive cavitation imaging when echogenic liposomes were insonified by the 500-kHz transducer. When stable cavitation was detected, delivery of the fluorophore into the arterial wall was observed. Increased echogenicity within the stent was also observed when echogenic liposomes were administered. Thus, both B-mode ultrasound imaging and cavitation imaging are feasible in the presence of an endovascular stent in vivo. Demonstration of this capability supports future studies to monitor restenosis with contrast-enhanced ultrasound and pursue image-guided ultrasound-mediated drug delivery to inhibit restenosis. Copyright © 2016 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  18. Laser-generated Micro-bubbles for Molecular Delivery to Adherent Cells

    NASA Astrophysics Data System (ADS)

    Genc, Suzanne Lee

    We examine the use of optical breakdown in aqueous media as a means to deliver molecules into live adherent cell cultures. This process, called optoinjection (OI), is affected both by the media composition and the cellular exposure to hydrodynamic stresses associated with the cavitation bubble formed by the optical breakdown process. Here we explore the possibility of performing OI using laser microbeams focused at low numerical aperture to provide conditions where OI can be performed at high-throughput. We first investigate the effect of media composition on plasma and cavitation bubble formation. We make the discovery that irradiation of minimal essential media, supports the formation of low-density plasmas (LDP) resulting in the generation of small (2--20 mum radius) cavitation bubbles. This provides gentle specific hydrodynamic perturbations to single or small groups of cells. The addition of supplemental fetal bovine serum to the medium prevents the formation LDPs and the resulting avalanche ionization generates larger (> 100 mum radius) bubbles and more violent hydrodynamic effects. Second, using high-speed photography we provide the first visualization of LDP-generated cavitation bubbles at precise offset locations relative to a boundary on which a cell monolayer can be cultured. These images depict the cellular exposure to different hydrodynamic conditions depending on the normalized offset distance (gamma = s/Rmax) and show how it affects the cellular exposure to shear stresses upon bubble expansion and different distributions of bubble energy upon collapse. Lastly, we examine the effects of pulse energy, parameters, and single vs. multiple laser exposures on the ability to deliver 3-5 kDa dextrans into adherent cells using both small (< 20 mum) and large (100mu m) radius bubbles. For single exposures, we identify several conditions under which OI can be optimized: (a) conditions where cell viability is maximized (˜90%) but optoinjection of viable cells is relatively low (˜30%) and (b) conditions where cell viability is compromised (˜80%) but where the optoinjection of viable cells is higher (˜50%). For multiple exposures in a grid pattern, we generally found reduced optoinjection efficacy but do identify conditions where we achieve injection of viable cells approaching 50%. We correlate these results to the cavitation bubble dynamics.

  19. Effects of HIFU induced cavitation on flooded lung parenchyma.

    PubMed

    Wolfram, Frank; Dietrich, Georg; Boltze, Carsten; Jenderka, Klaus Vitold; Lesser, Thomas Günther

    2017-01-01

    High intensity focused ultrasound (HIFU) has gained clinical interest as a non-invasive local tumour therapy in many organs. In addition, it has been shown that lung cancer can be targeted by HIFU using One-Lung Flooding (OLF). OLF generates a gas free saline-lung compound in one lung wing and therefore acoustic access to central lung tumours. It can be assumed that lung parenchyma is exposed to ultrasound intensities in the pre-focal path and in cases of misguiding. If so, cavitation might be induced in the saline fraction of flooded lung and cause tissue damage. Therefore this study was aimed to determine the thresholds of HIFU induced cavitation and tissue erosion in flooded lung. Resected human lung lobes were flooded ex-vivo. HIFU (1,1 MHz) was targeted under sonographic guidance into flooded lung parenchyma. Cavitation events were counted using subharmonic passive cavitation detection (PCD). B-Mode imaging was used to detect cavitation and erosion sonographically. Tissue samples out of the focal zone were analysed histologically. In flooded lung, a PCD and a sonographic cavitation detection threshold of 625  Wcm - 2 ( p r  = 4, 3  MPa ) and 3.600  Wcm - 2 ( p r  = 8, 3  MPa ) was found. Cavitation in flooded lung appears as blurred hyperechoic focal region, which enhances echogenity with insonation time. Lung parenchyma erosion was detected at intensities above 7.200  Wcm - 2 ( p r  = 10, 9  MPa ). Cavitation occurs in flooded lung parenchyma, which can be detected passively and by B-Mode imaging. Focal intensities required for lung tumour ablation are below levels where erosive events occur. Therefore focal cavitation events can be monitored and potential risk from tissue erosion in flooded lung avoided.

  20. Relations between acoustic cavitation and skin resistance during intermediate- and high-frequency sonophoresis.

    PubMed

    Rich, Kyle T; Hoerig, Cameron L; Rao, Marepalli B; Mast, T Douglas

    2014-11-28

    Enhanced skin permeability is known to be achieved during sonophoresis due to ultrasound-induced cavitation. However, the mechanistic role of cavitation during sonophoresis has been extensively investigated only for low-frequency (LFS, <100 kHz) applications. Here, mechanisms of permeability-enhancing stable and inertial cavitation were investigated by passively monitoring subharmonic and broadband emissions arising from cavitation isolated within or external to porcine skin in vitro during intermediate- (IFS, 100-700 kHz) and high-frequency sonophoresis (HFS, >1 MHz). The electrical resistance of skin, a surrogate measure of the permeability of skin to a variety of compounds, was measured to quantify the reduction and subsequent recovery of the skin barrier during and after exposure to pulsed (1 second pulse, 20% duty cycle) 0.41 and 2.0 MHz ultrasound over a range of acoustic powers (0-21.7 W) for 30 min. During IFS, significant skin resistance reductions and acoustic emissions from cavitation were measured exclusively when cavitation was isolated outside of the skin. Time-dependent skin resistance reductions measured during IFS correlated significantly with subharmonic and broadband emission levels. During HFS, significant skin resistance reductions were accompanied by significant acoustic emissions from cavitation measured during trials that isolated cavitation activity either outside of skin or within skin. Time-dependent skin resistance reductions measured during HFS correlated significantly greater with subharmonic than with broadband emission levels. The reduction of the skin barrier due to sonophoresis was reversible in all trials; however, effects incurred during IFS recovered more slowly and persisted over a longer period of time than HFS. These results quantitatively demonstrate the significance of cavitation during sonophoresis and suggest that the mechanisms and post-treatment longevity of permeability enhancement due to IFS and HFS treatments are different. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Cavitation phenomena in mechanical heart valves: studied by using a physical impinging rod system.

    PubMed

    Lo, Chi-Wen; Chen, Sheng-Fu; Li, Chi-Pei; Lu, Po-Chien

    2010-10-01

    When studying mechanical heart valve cavitation, a physical model allows direct flow field and pressure measurements that are difficult to perform with actual valves, as well as separate testing of water hammer and squeeze flow effects. Movable rods of 5 and 10 mm diameter impinged same-sized stationary rods to simulate squeeze flow. A 24 mm piston within a tube simulated water hammer. Adding a 5 mm stationary rod within the tube generated both effects simultaneously. Charged-coupled device (CCD) laser displacement sensors, strobe lighting technique, laser Doppler velocimetry (LDV), particle image velocimetry (PIV) and high fidelity piezoelectric pressure transducers measured impact velocities, cavitation images, squeeze flow velocities, vortices, and pressure changes at impact, respectively. The movable rods created cavitation at critical impact velocities of 1.6 and 1.2 m/s; squeeze flow velocities were 2.8 and 4.64 m/s. The isolated water hammer created cavitation at 1.3 m/s piston speed. The combined piston and stationary rod created cavitation at an impact speed of 0.9 m/s and squeeze flow of 3.2 m/s. These results show squeeze flow alone caused cavitation, notably at lower impact velocity as contact area increased. Water hammer alone also caused cavitation with faster displacement. Both effects together were additive. The pressure change at the vortex center was only 150 mmHg, which cannot generate the magnitude of pressure drop required for cavitation bubble formation. Cavitation occurred at 3-5 m/s squeeze flow, significantly different from the 14 m/s derived by Bernoulli's equation; the temporal acceleration of unsteady flow requires further study.

  2. Space Shuttle Main Engine Low Pressure Oxidizer Turbo-Pump Inducer Dynamic Environment Characterization through Water Model and Hot-Fire Testing

    NASA Technical Reports Server (NTRS)

    Arellano, Patrick; Patton, Marc; Schwartz, Alan; Stanton, David

    2006-01-01

    The Low Pressure Oxidizer Turbopump (LPOTP) inducer on the Block II configuration Space Shuttle Main Engine (SSME) experienced blade leading edge ripples during hot firing. This undesirable condition led to a minor redesign of the inducer blades. This resulted in the need to evaluate the performance and the dynamic environment of the redesign, relative to the current configuration, as part of the design acceptance process. Sub-scale water model tests of the two inducer configurations were performed, with emphasis on the dynamic environment due to cavitation induced vibrations. Water model tests were performed over a wide range of inlet flow coefficient and pressure conditions, representative of the scaled operating envelope of the Block II SSME, both in flight and in ground hot-fire tests, including all power levels. The water test hardware, facility set-up, type and placement of instrumentation, the scope of the test program, specific test objectives, data evaluation process and water test results that characterize and compare the two SSME LPOTP inducers are discussed. In addition, dynamic characteristics of the two water models were compared to hot fire data from specially instrumented ground tests. In general, good agreement between the water model and hot fire data was found, which confirms the value of water model testing for dynamic characterization of rocket engine turbomachinery.

  3. Effect of vibration amplitude on vapor cavitation in journal bearings

    NASA Astrophysics Data System (ADS)

    Brewe, D. E.; Jacobson, B. O.

    Computational movies were used to analyze the formation and collapse of vapor cavitation bubbles in a submerged journal bearing. The effect of vibration amplitude on vapor cavitation was studied for a journal undergoing circular whirl. The boundary conditions were implemented using Elrod's algorithm, which conserves mass flow through the cavitation bubble as well as through the oil-film region of the bearing. The vibration amplitudes for the different cases studied resulted in maximum eccentricity ratios ranging from 0.4 to 0.9. The minimum eccentricity ratio reached in each case was 0.1. For the least vibration amplitude studied in which the eccentricity ratio varied between 0.1 and 0.4, no vapor cavitation occurred. The largest vibration amplitude (i.e., eccentricity ratios of 0.1 to 0.9) resulted in vapor cavitation present 76 percent of one complete orbit.

  4. Singular value decomposition of received ultrasound signal to separate tissue, blood flow, and cavitation signals

    NASA Astrophysics Data System (ADS)

    Ikeda, Hayato; Nagaoka, Ryo; Lafond, Maxime; Yoshizawa, Shin; Iwasaki, Ryosuke; Maeda, Moe; Umemura, Shin-ichiro; Saijo, Yoshifumi

    2018-07-01

    High-intensity focused ultrasound is a noninvasive treatment applied by externally irradiating ultrasound to the body to coagulate the target tissue thermally. Recently, it has been proposed as a noninvasive treatment for vascular occlusion to replace conventional invasive treatments. Cavitation bubbles generated by the focused ultrasound can accelerate the effect of thermal coagulation. However, the tissues surrounding the target may be damaged by cavitation bubbles generated outside the treatment area. Conventional methods based on Doppler analysis only in the time domain are not suitable for monitoring blood flow in the presence of cavitation. In this study, we proposed a novel filtering method based on the differences in spatiotemporal characteristics, to separate tissue, blood flow, and cavitation by employing singular value decomposition. Signals from cavitation and blood flow were extracted automatically using spatial and temporal covariance matrices.

  5. Application of Hydrodynamic Cavitation for Food and Bioprocessing

    NASA Astrophysics Data System (ADS)

    Gogate, Parag R.

    Hydrodynamic cavitation can be simply generated by the alterations in the flow field in high speed/high pressure devices and also by passage of the liquid through a constriction such as orifice plate, venturi, or throttling valve. Hydrodynamic cavitation results in the formation of local hot spots, release of highly reactive free radicals, and enhanced mass transfer rates due to turbulence generated as a result of liquid circulation currents. These conditions can be suitably applied for intensification of different bioprocessing applications in an energy-efficient manner as compared to conventionally used ultrasound-based reactors. The current chapter aims at highlighting different aspects related to hydrodynamic cavitation, including the theoretical aspects for optimization of operating parameters, reactor designs, and overview of applications relevant to food and bioprocessing. Some case studies highlighting the comparison of hydrodynamic cavitation and acoustic cavitation reactors will also be discussed.

  6. Effect of vibration amplitude on vapor cavitation in journal bearings

    NASA Technical Reports Server (NTRS)

    Brewe, D. E.; Jacobson, B. O.

    1986-01-01

    Computational movies were used to analyze the formation and collapse of vapor cavitation bubbles in a submerged journal bearing. The effect of vibration amplitude on vapor cavitation was studied for a journal undergoing circular whirl. The boundary conditions were implemented using Elrod's algorithm, which conserves mass flow through the cavitation bubble as well as through the oil-film region of the bearing. The vibration amplitudes for the different cases studied resulted in maximum eccentricity ratios ranging from 0.4 to 0.9. The minimum eccentricity ratio reached in each case was 0.1. For the least vibration amplitude studied in which the eccentricity ratio varied between 0.1 and 0.4, no vapor cavitation occurred. The largest vibration amplitude (i.e., eccentricity ratios of 0.1 to 0.9) resulted in vapor cavitation present 76 percent of one complete orbit.

  7. Hydrodynamic cavitation in microsystems. I. Experiments with deionized water and nanofluids

    NASA Astrophysics Data System (ADS)

    Medrano, M.; Zermatten, P. J.; Pellone, C.; Franc, J. P.; Ayela, F.

    2011-12-01

    An experimental study of hydrodynamic cavitation downstream microdiaphragms and microventuris is presented. Deionized water and nanofluids have been characterized within silicon-Pyrex micromachined devices with hydraulic diameters ranging from 51 μm to 104 μm. The input pressure could reach up to 10 bars, and the flow rate was below 1 liter per hour. The output pressure of the devices was fixed at values ranging from 0.3 bar to 2 bars, so that it was possible to study the evolution of the cavitation number as a function of the Reynolds number in the orifice of the diaphragms or in the throat of the venturis. A delay on the onset of cavitation has been recorded for all the devices when they are fed with deionized water, because of the metastability of the liquid and because of the lack of roughness of the walls. For the first time, hydrodynamic cavitation of nanofluids (nanoparticles dispersed into the liquid) has been considered. The presence of nano-aggregates in the liquid does not exhibit any noticeable effect on the cavitation threshold through the venturis. However, such a presence has a strong influence on the cavitation onset in microdiaphragms: above a critical volume solid concentration of ≈10-5, the metastability is broken and the nanofluids behave as tap water filled up with large nuclei. These microdevices, where a low amount of fluid is required to reach cavitating flows, appear to be useful tools in order to study cavitating phenomena in localized area with specific fluids.

  8. Characterizing the cavitation development and acoustic spectrum in various liquids.

    PubMed

    Tzanakis, I; Lebon, G S B; Eskin, D G; Pericleous, K A

    2017-01-01

    A bespoke cavitometer that measures acoustic spectrum and is capable of operating in a range of temperatures (up to 750°C) was used to study the cavitation behaviour in three transparent liquids and in molten aluminium. To relate these acoustic measurements to cavitation development, the dynamics of the cavitation bubble structures was observed in three Newtonian, optically transparent liquids with significantly different physical properties: water, ethanol, and glycerine. Each liquid was treated at 20kHz with a piezoelectric ultrasonic transducer coupled to a titanium sonotrode with a tip diameter of 40mm. Two different transducer power levels were deployed: 50% and 100%, with the maximum power corresponding to a peak-to-peak amplitude of 17μm. The cavitation structures and the flow patterns were filmed with a digital camera. To investigate the effect of distance from the ultrasound source on the cavitation intensity, acoustic emissions were measured with the cavitometer at two points: below the sonotrode and near the edge of the experimental vessel. The behaviour of the three tested liquids was very different, implying that their physical parameters played a decisive role in the establishment of the cavitation regime. Non dimensional analysis revealed that water shares the closest cavitation behaviour with liquid aluminium and can therefore be used as its physical analogue in cavitation studies; this similarity was also confirmed when comparing the measured acoustic spectra of water and liquid aluminium. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.

  9. Observation of cavitation in a mechanical heart valve in a total artificial heart.

    PubMed

    Lee, Hwansung; Tsukiya, Tomonori; Homma, Akihiko; Kamimura, Tadayuki; Takewa, Yoshiaki; Nishinaka, Tomohiro; Tatsumi, Eisuke; Taenaka, Yoshiyuki; Takano, Hisateru; Kitamura, Soichiro

    2004-01-01

    Recently, cavitation on the surface of mechanical heart valves has been studied as a cause of fractures occurring in implanted mechanical heart valves. The cause of cavitation in mechanical heart valves was investigated using the 25 mm Medtronic Hall valve and the 23 mm Omnicarbon valve. Closing of these valves in the mitral position was simulated in an electrohydraulic totally artificial heart. Tests were conducted under physiologic pressures at heart rates from 60 to 100 beats per minute with cardiac outputs from 4.8 to 7.7 L/min. The disk closing motion was measured by a laser displacement sensor. A high-speed video camera was used to observe the cavitation bubbles in the mechanical heart valves. The maximum closing velocity of the Omnicarbon valve was faster than that of the Medtronic Hall valve. In both valves, the closing velocity of the leaflet, used as the cavitation threshold, was approximately 1.3-1.5 m/s. In the case of the Medtronic Hall valve, cavitation bubbles were generated by the squeeze flow and by the effects of the venturi and the water hammer. With the Omnicarbon valve, the cavitation bubbles were generated by the squeeze flow and the water hammer. The mechanism leading to the development of cavitation bubbles depended on the valve closing velocity and the valve stop geometry. Most of the cavitation bubbles were observed around the valve stop and were generated by the squeeze flow.

  10. Effects of ultrasonic and hydrodynamic cavitation on the treatment of cork wastewater by flocculation and Fenton processes.

    PubMed

    Wu, Zhilin; Yuste-Córdoba, Francisco J; Cintas, Pedro; Wu, Zhansheng; Boffa, Luisa; Mantegna, Stefano; Cravotto, Giancarlo

    2018-01-01

    This paper reports that ultrasonic (US) and hydrodynamic cavitation (HC) are efficient strategies for the environmental remediation of cork wastewater (CW). It is necessary to remove toxic, inhibitory or refractory organic matter from CW using physical and chemical techniques (pre-treatment) prior to performing conventional biological treatment. After this biological treatment, it is also critical to further decontaminate (post-treatment) in order to meet the discharge limitation. The pre-treatment of diluted CW using Fenton oxidation (FE) alone led to COD and polyphenol (PP) removal values of 30% and 61%, respectively, while HC and US resulted in 83-90% increases in COD reduction and 26-33% increases in PP reduction. Whereas 55% and 91% COD and PP removal were achieved using flocculation (Floc) alone, COD elimination was increased by a further 7-18% under HC and US. No noticeable improvement in PP elimination was observed. US did not enhance the Floc decontamination of the original concentrated CW, however, considerable quantities of white biofilm were surprisingly generated on the CW surface after the pre-treatment, thus indicating the improvement of biodegradability of the resulting liquid. In fact, the post-treatment stage, using FE alone after having filtered the biofilms, led to reductions of 53% in COD and 90% in PP. The HC and US protocols resulted in 26-34% increases in COD elimination. HC further enhanced PP elimination caused by FE, while US resulted in lower levels of PP elimination. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Dynamic and interaction of fs-laser induced cavitation bubbles for analyzing the cutting effect

    NASA Astrophysics Data System (ADS)

    Tinne, N.; Schumacher, S.; Nuzzo, V.; Ripken, T.; Lubatschowski, H.

    2009-07-01

    A prominent laser based treatment in ophthalmology is the LASIK procedure which nowadays includes a cutting of the corneal tissue based on ultra short pulses. Focusing an ultra short laser pulse below the surface of biological tissue an optical breakdown is caused and hence a dissection is obtained. The laser energy of the laser pulses is absorbed by nonlinear processes. As a result a cavitation bubble expands and ruptures the tissue. Hence positioning of several optical breakdowns side by side generates an incision. Due to a reduction of the duration of the treatment the current development of ultra short laser systems points to higher repetition rates in the range of hundreds of KHz or even MHz instead of tens of kHz. This in turn results in a probable occurrence of interaction between different optical breakdowns and respectively cavitation bubbles of adjacent optical breakdowns. While the interaction of one single laser pulse with biological tissue is analyzed reasonably well experimentally and theoretically, the interaction of several spatial and temporal following pulses is scarcely determined yet. Thus the aim of this study is to analyse the dynamic and interaction of two cavitation bubbles by using high speed photography. The applied laser pulse energy, the energy ratio and the spot distance between different cavitation bubbles were varied. Depending on a change of these parameters different kinds of interactions such as a flattening and deformation of bubble shape or jet formation are observed. Based on these results a further research seems to be inevitable to comprehend and optimize the cutting effect of ultra short pulse laser systems with high (> 1 MHz) repetition rates.

  12. Computation and analysis of cavitating flow in Francis-class hydraulic turbines

    NASA Astrophysics Data System (ADS)

    Leonard, Daniel J.

    Hydropower is the most proven renewable energy technology, supplying the world with 16% of its electricity. Conventional hydropower generates a vast majority of that percentage. Although a mature technology, hydroelectric generation shows great promise for expansion through new dams and plants in developing hydro countries. Moreover, in developed hydro countries, such as the United States, installing generating units in existing dams and the modern refurbishment of existing plants can greatly expand generating capabilities with little to no further impact on the environment. In addition, modern computational technology and fluid dynamics expertise has led to substantial improvements in modern turbine design and performance. Cavitation has always presented a problem in hydroturbines, causing performance breakdown, erosion, damage, vibration, and noise. While modern turbines are usually designed to be cavitation-free at their best efficiency point, due to the variable demand of the energy market it is fairly common to operate at off-design conditions. Here, cavitation and its deleterious effects are unavoidable, and hence, cavitation is a limiting factor on the design and operation of these turbines. Multiphase Computational Fluid Dynamics (CFD) has been used in recent years to model cavitating flow for a large range of problems, including turbomachinery. However, CFD of cavitating flow in hydroturbines is still in its infancy. This dissertation presents steady-periodic Reynolds-averaged Navier-Stokes simulations of a cavitating Francis-class hydroturbine at model and prototype scales. Computational results of the reduced-scale model and full-scale prototype, undergoing performance breakdown, are compared with empirical model data and prototype performance estimations based on standard industry scalings from the model data. Mesh convergence of the simulations is also displayed. Comparisons are made between the scales to display that cavitation performance breakdown can occur more abruptly in the model than the prototype, due to lack of Froude similitude between the two. When severe cavitation occurs, clear differences are observed in vapor content between the scales. A stage-by-stage performance decomposition is conducted to analyze the losses within individual components of each scale of the machine. As cavitation becomes more severe, the losses in the draft tube account for an increasing amount of the total losses in the machine. More losses occur in the model draft tube as cavitation formation in the prototype draft tube is prevented by the larger hydrostatic pressure gradient across the machine. Additionally, unsteady Detached Eddy Simulations of the fully-coupled cavitating hydroturbine are performed for both scales. Both mesh and temporal convergence studies are provided. The temporal and spectral content of fluctuations in torque and pressure are monitored and compared between single-phase, cavitating, model, and prototype cases. A shallow draft tube induced runner imbalance results in an asymmetric vapor distribution about the runner, leading to more extensive growth and collapse of vapor on any individual blade as it undergoes a revolution. Unique frequency components manifest and persist through the entire machine only when cavitation is present in the hub vortex. Large maximum pressure spikes, which result from vapor collapse, are observed on the blade surfaces in the multiphase simulations, and these may be a potential source of cavitation damage and erosion. Multiphase CFD is shown to be an accurate and effective technique for simulating and analyzing cavitating flow in Francis-class hydraulic turbines. It is recommended that it be used as an industrial tool to supplement model cavitation experiments for all types of hydraulic turbines. Moreover, multiphase CFD can be equally effective as a research tool, to investigate mechanisms of cavitating hydraulic turbines that are not understood, and to uncover unique new phenomena which are currently unknown.

  13. Kidney stone erosion by micro scale hydrodynamic cavitation and consequent kidney stone treatment.

    PubMed

    Perk, Osman Yavuz; Şeşen, Muhsincan; Gozuacik, Devrim; Koşar, Ali

    2012-09-01

    The objective of this study is to reveal the potential of micro scale hydrodynamic bubbly cavitation for the use of kidney stone treatment. Hydrodynamically generated cavitating bubbles were targeted to the surfaces of 18 kidney stone samples made of calcium oxalate, and their destructive effects were exploited in order to remove kidney stones in in vitro experiments. Phosphate buffered saline (PBS) solution was used as the working fluid under bubbly cavitating conditions in a 0.75 cm long micro probe of 147 μm inner diameter at 9790 kPa pressure. The surface of calcium oxalate type kidney stones were exposed to bubbly cavitation at room temperature for 5 to 30 min. The eroded kidney stones were visually analyzed with a high speed CCD camera and using SEM (scanning electron microscopy) techniques. The experiments showed that at a cavitation number of 0.017, hydrodynamic bubbly cavitation device could successfully erode stones with an erosion rate of 0.31 mg/min. It was also observed that the targeted application of the erosion with micro scale hydrodynamic cavitation may even cause the fracture of the kidney stones within a short time of 30 min. The proposed treatment method has proven to be an efficient instrument for destroying kidney stones.

  14. Mechanism of water-stress induced cavitation in conifers: bordered pit structure and function support the hypothesis of seal capillary-seeding

    PubMed Central

    DELZON, SYLVAIN; DOUTHE, CYRIL; SALA, ANNA; COCHARD, HERVE

    2010-01-01

    Resistance to water-stress induced cavitation is an important indicator of drought tolerance in woody species and is known to be intimately linked to the anatomy of the xylem. However, the actual mechanical properties of the pit membrane are not well known and the exact mode of air-seeding by which cavitation occurs is still uncertain. We examined the relationship between cavitation resistance and bordered pit structure and function in 40 coniferous species. Xylem pressure inducing 50% loss of hydraulic conductance (P50, a proxy for cavitation resistance) varied widely among species, from −2.9 to −11.3 MPa. The valve effect of the pit membrane, measured as a function of margo flexibility and torus overlap, explained more variation in cavitation-resistance than simple anatomical traits such as pit membrane, pit aperture or torus size. Highly cavitation resistant species exhibited both a high flexibility of the margo and a large overlap between the torus and the pit aperture, allowing the torus to tightly seal the pit aperture. Our results support the hypothesis of seal capillary-seeding as the most likely mode of air-seeding, and suggest that the adhesion of the torus to the pit border may be the main determinant of cavitation resistance in conifers. PMID:20636490

  15. Effect of gold nanoparticle size on acoustic cavitation using chemical dosimetry method.

    PubMed

    Shanei, Ahmad; Shanei, Mohammad Mahdi

    2017-01-01

    When a liquid is irradiated with high intensities of ultrasound irradiation, acoustic cavitation occurs. Acoustic cavitation generates free radicals from the breakdown of water and other molecules. Cavitation can be fatal to cells and is utilized to destroy cancer tumors. The existence of particles in liquid provides nucleation sites for cavitation bubbles and leads to decrease the ultrasonic intensity threshold needed for cavitation onset. In the present investigation, the effect of gold nanoparticles with appropriate amount and size on the acoustic cavitation activity has been shown by determining hydroxyl radicals in terephthalic acid solutions containing 15, 20, 28 and 35nm gold nanoparticles sizes by using 1MHz low level ultrasound. The effect of sonication intensity in hydroxyl radical production was considered. The recorded fluorescence signal in terephthalic acid solutions containing gold nanoparticles was considerably higher than the terephthalic acid solutions without gold nanoparticles at different intensities of ultrasound irradiation. Also, the results showed that the recorded fluorescence signal intensity in terephthalic acid solution containing finer size of gold nanoparticles was lower than the terephthalic acid solutions containing larger size of gold nanoparticles. Acoustic cavitation in the presence of gold nanoparticles can be used as a way for improving therapeutic effects on the tumors. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Cavitation of deep lacunar infarcts in patients with first-ever lacunar stroke: a 2-year follow-up study with MR.

    PubMed

    Loos, Caroline M J; Staals, Julie; Wardlaw, Joanna M; van Oostenbrugge, Robert J

    2012-08-01

    Studies in patients with lacunar stroke often assess the number of lacunes. However, data on how many symptomatic lacunar infarcts cavitate into a lacune are limited. We assessed the evolution of symptomatic lacunar infarcts over 2-year follow-up. In 82 patients with first-ever lacunar stroke with a lacunar infarct in the deep brain regions (excluding the centrum semiovale), we performed a brain MR at presentation and 2 years later. We classified cavitation of lacunar infarcts at baseline and on follow-up MR as absent, incomplete, or complete. We recorded time to imaging, infarct size, and vascular risk factors. On baseline MR, 38 (46%) index infarcts showed complete or incomplete cavitation. Median time to imaging was 8 (0-73) days in noncavitated and 63 (1-184) days in cavitated lesions (P<0.05). On follow-up imaging, 94% of the lacunar infarcts were completely or incompletely cavitated, most had reduced in diameter, and 5 (6%) had disappeared. Vascular risk factors were not associated with cavitation. Cavitation and lesion shrinkage were seen in almost all symptomatic lacunar infarcts in the deep brain regions over 2-year follow-up. Counting lacunes in these specific regions at a random moment might slightly, however not substantially, underestimate the burden of deep lacunar infarction.

  17. The cavitation erosion of ultrasonic sonotrode during large-scale metallic casting: Experiment and simulation.

    PubMed

    Tian, Yang; Liu, Zhilin; Li, Xiaoqian; Zhang, Lihua; Li, Ruiqing; Jiang, Ripeng; Dong, Fang

    2018-05-01

    Ultrasonic sonotrodes play an essential role in transmitting power ultrasound into the large-scale metallic casting. However, cavitation erosion considerably impairs the in-service performance of ultrasonic sonotrodes, leading to marginal microstructural refinement. In this work, the cavitation erosion behaviour of ultrasonic sonotrodes in large-scale castings was explored using the industry-level experiments of Al alloy cylindrical ingots (i.e. 630 mm in diameter and 6000 mm in length). When introducing power ultrasound, severe cavitation erosion was found to reproducibly occur at some specific positions on ultrasonic sonotrodes. However, there is no cavitation erosion present on the ultrasonic sonotrodes that were not driven by electric generator. Vibratory examination showed cavitation erosion depended on the vibration state of ultrasonic sonotrodes. Moreover, a finite element (FE) model was developed to simulate the evolution and distribution of acoustic pressure in 3-D solidification volume. FE simulation results confirmed that significant dynamic interaction between sonotrodes and melts only happened at some specific positions corresponding to severe cavitation erosion. This work will allow for developing more advanced ultrasonic sonotrodes with better cavitation erosion-resistance, in particular for large-scale castings, from the perspectives of ultrasonic physics and mechanical design. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Characterization of acoustic cavitation in water and molten aluminum alloy.

    PubMed

    Komarov, Sergey; Oda, Kazuhiro; Ishiwata, Yasuo; Dezhkunov, Nikolay

    2013-03-01

    High-intensive ultrasonic vibrations have been recognized as an attractive tool for refining the grain structure of metals in casting technology. However, the practical application of ultrasonics in this area remains rather limited. One of the reasons is a lack of data needed to optimize the ultrasonic treatment conditions, particularly those concerning characteristics of cavitation zone in molten aluminum. The main aim of the present study was to investigate the intensity and spectral characteristics of cavitation noise generated during radiation of ultrasonic waves into water and molten aluminum alloys, and to establish a measure for evaluating the cavitation intensity. The measurements were performed by using a high temperature cavitometer capable of measuring the level of cavitation noise within five frequency bands from 0.01 to 10MHz. The effect of cavitation treatment was verified by applying high-intense ultrasonic vibrations to a DC caster to refine the primary silicon grains of a model Al-17Si alloy. It was found that the level of high frequency noise components is the most adequate parameter for evaluating the cavitation intensity. Based on this finding, it was concluded that implosions of cavitation bubbles play a decisive role in refinement of the alloy structure. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Mechanism of water-stress induced cavitation in conifers: bordered pit structure and function support the hypothesis of seal capillary-seeding.

    PubMed

    Delzon, Sylvain; Douthe, Cyril; Sala, Anna; Cochard, Herve

    2010-12-01

    Resistance to water-stress induced cavitation is an important indicator of drought tolerance in woody species and is known to be intimately linked to the anatomy of the xylem. However, the actual mechanical properties of the pit membrane are not well known and the exact mode of air-seeding by which cavitation occurs is still uncertain. We examined the relationship between cavitation resistance and bordered pit structure and function in 40 coniferous species. Xylem pressure inducing 50% loss of hydraulic conductance (P(50), a proxy for cavitation resistance) varied widely among species, from -2.9 to -11.3 MPa. The valve effect of the pit membrane, measured as a function of margo flexibility and torus overlap, explained more variation in cavitation-resistance than simple anatomical traits such as pit membrane, pit aperture or torus size. Highly cavitation resistant species exhibited both a high flexibility of the margo and a large overlap between the torus and the pit aperture, allowing the torus to tightly seal the pit aperture. Our results support the hypothesis of seal capillary-seeding as the most likely mode of air-seeding, and suggest that the adhesion of the torus to the pit border may be the main determinant of cavitation resistance in conifers. © 2010 Blackwell Publishing Ltd.

  20. Use of hydrodynamic cavitation in (waste)water treatment.

    PubMed

    Dular, Matevž; Griessler-Bulc, Tjaša; Gutierrez-Aguirre, Ion; Heath, Ester; Kosjek, Tina; Krivograd Klemenčič, Aleksandra; Oder, Martina; Petkovšek, Martin; Rački, Nejc; Ravnikar, Maja; Šarc, Andrej; Širok, Brane; Zupanc, Mojca; Žitnik, Miha; Kompare, Boris

    2016-03-01

    The use of acoustic cavitation for water and wastewater treatment (cleaning) is a well known procedure. Yet, the use of hydrodynamic cavitation as a sole technique or in combination with other techniques such as ultrasound has only recently been suggested and employed. In the first part of this paper a general overview of techniques that employ hydrodynamic cavitation for cleaning of water and wastewater is presented. In the second part of the paper the focus is on our own most recent work using hydrodynamic cavitation for removal of pharmaceuticals (clofibric acid, ibuprofen, ketoprofen, naproxen, diclofenac, carbamazepine), toxic cyanobacteria (Microcystis aeruginosa), green microalgae (Chlorella vulgaris), bacteria (Legionella pneumophila) and viruses (Rotavirus) from water and wastewater. As will be shown, hydrodynamic cavitation, like acoustic, can manifest itself in many different forms each having its own distinctive properties and mechanisms. This was until now neglected, which eventually led to poor performance of the technique. We will show that a different type of hydrodynamic cavitation (different removal mechanism) is required for successful removal of different pollutants. The path to use hydrodynamic cavitation as a routine water cleaning method is still long, but recent results have already shown great potential for optimisation, which could lead to a low energy tool for water and wastewater cleaning. Copyright © 2015 Elsevier B.V. All rights reserved.

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