Atmospheric considerations regarding the impact of heat dissipation from a nuclear energy center

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rotty, R.M.; Bauman, H.; Bennett, L.L.

1976-05-01

Potential changes in climate resulting from a large nuclear energy center are discussed. On a global scale, no noticeable changes are likely, but on both a regional and a local scale, changes can be expected. Depending on the cooling system employed, the amount of fog may increase, the amount and distribution of precipitation will change, and the frequency or location of severe storms may change. Very large heat releases over small surface areas can result in greater atmospheric instability; a large number of closely spaced natural-draft cooling towers have this disadvantage. On the other hand, employment of natural-draft towers makesmore » an increase in the occurrence of ground fog unlikely. The analysis suggests that the cooling towers for a large nuclear energy center should be located in clusters of four with at least 2.5-mile spacing between the clusters. This is equivalent to the requirement of one acre of land surface per each two megawatts of heat being rejected.« less

Large-scale Labeled Datasets to Fuel Earth Science Deep Learning Applications

NASA Astrophysics Data System (ADS)

Maskey, M.; Ramachandran, R.; Miller, J.

2017-12-01

Deep learning has revolutionized computer vision and natural language processing with various algorithms scaled using high-performance computing. However, generic large-scale labeled datasets such as the ImageNet are the fuel that drives the impressive accuracy of deep learning results. Large-scale labeled datasets already exist in domains such as medical science, but creating them in the Earth science domain is a challenge. While there are ways to apply deep learning using limited labeled datasets, there is a need in the Earth sciences for creating large-scale labeled datasets for benchmarking and scaling deep learning applications. At the NASA Marshall Space Flight Center, we are using deep learning for a variety of Earth science applications where we have encountered the need for large-scale labeled datasets. We will discuss our approaches for creating such datasets and why these datasets are just as valuable as deep learning algorithms. We will also describe successful usage of these large-scale labeled datasets with our deep learning based applications.

Mobility Data Analytics Center.

DOT National Transportation Integrated Search

2016-01-01

Mobility Data Analytics Center aims at building a centralized data engine to efficiently manipulate : large-scale data for smart decision making. Integrating and learning the massive data are the key to : the data engine. The ultimate goal of underst...

A High Resolution View of Galactic Centers: Arp 220 and M31

NASA Astrophysics Data System (ADS)

Lockhart, Kelly E.

The centers of galaxy are small in size and yet incredibly complex. They play host to supermassive black holes and nuclear star clusters (NSCs) and are subject to large gas inows, nuclear starbursts, and active galactic nuclear (AGN) activity. They can also be the launching site for large-scale galactic outows. However, though these systems are quite important to galactic evolution, observations are quite difficult due to their small size. Using high spatial resolution narrowband imaging with HST/WFC3 of Arp 220, a latestage galaxy merger, I discover an ionized gas bubble feature ( r = 600 pc) just off the nucleus. The bubble is aligned with both the western nucleus and with the large-scale galactic outflow. Using energetics arguments, I link the bubble with a young, obscured AGN or with an intense nuclear starburst. Given its alignment along the large-scale outflow axis, I argue that the bubble presents evidence for a link between the galactic center and the large-scale outflow. I also present new observations of the NSC in M31, the closest large spiral galaxy to our own. Using the OSIRIS near-infrared integral field spectrograph (IFS) on Keck, I map the kinematics of the old stellar population in the eccentric disk of the NSC. I compare the observations to models to derive a precession speed of the disk of 0+/-5 km s-1 pc-1 , and hence confirm that winds from the old stellar population may be the source of gas needed to form the young stellar population in the NSC. Studies of galactic centers are dependent on high spatial resolution observations. In particular, IFSs are ideal instruments for these studies as they provide two-dimensional spectroscopy of the field of view, enabling 2D kinematic studies. I report on work to characterize and improve the data reduction pipeline of the OSIRIS IFS, and discuss implications for future generations of IFS instrumentation.

Measured acoustic characteristics of ducted supersonic jets at different model scales

NASA Technical Reports Server (NTRS)

Jones, R. R., III; Ahuja, K. K.; Tam, Christopher K. W.; Abdelwahab, M.

1993-01-01

A large-scale (about a 25x enlargement) model of the Georgia Tech Research Institute (GTRI) hardware was installed and tested in the Propulsion Systems Laboratory of the NASA Lewis Research Center. Acoustic measurements made in these two facilities are compared and the similarity in acoustic behavior over the scale range under consideration is highlighted. The study provide the acoustic data over a relatively large-scale range which may be used to demonstrate the validity of scaling methods employed in the investigation of this phenomena.

Potential utilization of the NASA/George C. Marshall Space Flight Center in earthquake engineering research

NASA Technical Reports Server (NTRS)

Scholl, R. E. (Editor)

1979-01-01

Earthquake engineering research capabilities of the National Aeronautics and Space Administration (NASA) facilities at George C. Marshall Space Flight Center (MSFC), Alabama, were evaluated. The results indicate that the NASA/MSFC facilities and supporting capabilities offer unique opportunities for conducting earthquake engineering research. Specific features that are particularly attractive for large scale static and dynamic testing of natural and man-made structures include the following: large physical dimensions of buildings and test bays; high loading capacity; wide range and large number of test equipment and instrumentation devices; multichannel data acquisition and processing systems; technical expertise for conducting large-scale static and dynamic testing; sophisticated techniques for systems dynamics analysis, simulation, and control; and capability for managing large-size and technologically complex programs. Potential uses of the facilities for near and long term test programs to supplement current earthquake research activities are suggested.

Spatial and temporal distribution of pore gas concentrations during mainstream large-scale trough composting in China.

PubMed

Zeng, Jianfei; Shen, Xiuli; Sun, Xiaoxi; Liu, Ning; Han, Lujia; Huang, Guangqun

2018-05-01

With the advantages of high treatment capacity and low operational cost, large-scale trough composting has become one of the mainstream composting patterns in composting plants in China. This study measured concentrations of O 2 , CO 2 , CH 4 and NH 3 on-site to investigate the spatial and temporal distribution of pore gas concentrations during mainstream large-scale trough composting in China. The results showed that the temperature in the center of the pile was obviously higher than that in the side of the pile. Pore O 2 concentration rapidly decreased and maintained <5% (in volume) for 38 days or more in both the center and side of the pile and effective O 2 diffusion occurred at most in every two contiguous layers. Pore CO 2 and CH 4 concentrations at each measurement point were positively correlated (0.436 ≤ r ≤ 0.570, P < 0.01) and the concentrations in the side of the pile were obviously lower than those in the center. The top layer exhibited highest pore O 2 concentration and lowest CO 2 and CH 4 concentrations, and the bottom layer was on the contrary. No significant differences in pore NH 3 concentrations between different layers or between different measurement points in the same layer were found. Therefore, mixing the center and the side of the pile when mechanical turning and adjusting the height of the pile according to the physical properties of bulking agents are suggested to optimize the oxygen distribution and promote the composting process during large-scale trough composting when the pile was naturally aerated, which will contribute to improving the current undesirable atmosphere environment in China. Copyright © 2018 Elsevier Ltd. All rights reserved.

A study on large-scale nudging effects in regional climate model simulation

NASA Astrophysics Data System (ADS)

Yhang, Yoo-Bin; Hong, Song-You

2011-05-01

The large-scale nudging effects on the East Asian summer monsoon (EASM) are examined using the National Centers for Environmental Prediction (NCEP) Regional Spectral Model (RSM). The NCEP/DOE reanalysis data is used to provide large-scale forcings for RSM simulations, configured with an approximately 50-km grid over East Asia, centered on the Korean peninsula. The RSM with a variant of spectral nudging, that is, the scale selective bias correction (SSBC), is forced by perfect boundary conditions during the summers (June-July-August) from 1979 to 2004. The two summers of 2000 and 2004 are investigated to demonstrate the impact of SSBC on precipitation in detail. It is found that the effect of SSBC on the simulated seasonal precipitation is in general neutral without a discernible advantage. Although errors in large-scale circulation for both 2000 and 2004 are reduced by using the SSBC method, the impact on simulated precipitation is found to be negative in 2000 and positive in 2004 summers. One possible reason for a different effect is that precipitation in the summer of 2004 is characterized by a strong baroclinicity, while precipitation in 2000 is caused by thermodynamic instability. The reduction of convective rainfall over the oceans by the application of the SSBC method seems to play an important role in modeled atmosphere.

The Limits and Possibilities of International Large-Scale Assessments. Education Policy Brief. Volume 9, Number 2, Spring 2011

ERIC Educational Resources Information Center

Rutkowski, David J.; Prusinski, Ellen L.

2011-01-01

The staff of the Center for Evaluation & Education Policy (CEEP) at Indiana University is often asked about how international large-scale assessments influence U.S. educational policy. This policy brief is designed to provide answers to some of the most frequently asked questions encountered by CEEP researchers concerning the three most popular…

Experimental feasibility study of the application of magnetic suspension techniques to large-scale aerodynamic test facilities. [cryogenic traonics wind tunnel

NASA Technical Reports Server (NTRS)

Zapata, R. N.; Humphris, R. R.; Henderson, K. C.

1975-01-01

Based on the premises that magnetic suspension techniques can play a useful role in large scale aerodynamic testing, and that superconductor technology offers the only practical hope for building large scale magnetic suspensions, an all-superconductor 3-component magnetic suspension and balance facility was built as a prototype and tested sucessfully. Quantitative extrapolations of design and performance characteristics of this prototype system to larger systems compatible with existing and planned high Reynolds number facilities at Langley Research Center were made and show that this experimental technique should be particularly attractive when used in conjunction with large cryogenic wind tunnels.

Engineering a Large Scale Indium Nanodot Array for Refractive Index Sensing.

PubMed

Xu, Xiaoqing; Hu, Xiaolin; Chen, Xiaoshu; Kang, Yangsen; Zhang, Zhiping; B Parizi, Kokab; Wong, H-S Philip

2016-11-23

In this work, we developed a simple method to fabricate 12 × 4 mm 2 large scale nanostructure arrays and investigated the feasibility of indium nanodot (ND) array with different diameters and periods for refractive index sensing. Absorption resonances at multiple wavelengths from the visible to the near-infrared range were observed for various incident angles in a variety of media. Engineering the ND array with a centered square lattice, we successfully enhanced the sensitivity by 60% and improved the figure of merit (FOM) by 190%. The evolution of the resonance dips in the reflection spectra, of square lattice and centered square lattice, from air to water, matches well with the results of Lumerical FDTD simulation. The improvement of sensitivity is due to the enhancement of local electromagnetic field (E-field) near the NDs with centered square lattice, as revealed by E-field simulation at resonance wavelengths. The E-field is enhanced due to coupling between the two square ND arrays with [Formula: see text]x period at phase matching. This work illustrates an effective way to engineer and fabricate a refractive index sensor at a large scale. This is the first experimental demonstration of poor-metal (indium) nanostructure array for refractive index sensing. It also demonstrates a centered square lattice for higher sensitivity and as a better basic platform for more complex sensor designs.

An Overview of NASA Efforts on Zero Boiloff Storage of Cryogenic Propellants

NASA Technical Reports Server (NTRS)

Hastings, Leon J.; Plachta, D. W.; Salerno, L.; Kittel, P.; Haynes, Davy (Technical Monitor)

2001-01-01

Future mission planning within NASA has increasingly motivated consideration of cryogenic propellant storage durations on the order of years as opposed to a few weeks or months. Furthermore, the advancement of cryocooler and passive insulation technologies in recent years has substantially improved the prospects for zero boiloff storage of cryogenics. Accordingly, a cooperative effort by NASA's Ames Research Center (ARC), Glenn Research Center (GRC), and Marshall Space Flight Center (MSFC) has been implemented to develop and demonstrate "zero boiloff" concepts for in-space storage of cryogenic propellants, particularly liquid hydrogen and oxygen. ARC is leading the development of flight-type cryocoolers, GRC the subsystem development and small scale testing, and MSFC the large scale and integrated system level testing. Thermal and fluid modeling involves a combined effort by the three Centers. Recent accomplishments include: 1) development of "zero boiloff" analytical modeling techniques for sizing the storage tankage, passive insulation, cryocooler, power source mass, and radiators; 2) an early subscale demonstration with liquid hydrogen 3) procurement of a flight-type 10 watt, 95 K pulse tube cryocooler for liquid oxygen storage and 4) assembly of a large-scale test article for an early demonstration of the integrated operation of passive insulation, destratification/pressure control, and cryocooler (commercial unit) subsystems to achieve zero boiloff storage of liquid hydrogen. Near term plans include the large-scale integrated system demonstration testing this summer, subsystem testing of the flight-type pulse-tube cryocooler with liquid nitrogen (oxygen simulant), and continued development of a flight-type liquid hydrogen pulse tube cryocooler.

Preschool Center Quality and School Readiness: Quality Effects and Variation by Demographic and Child Characteristics

ERIC Educational Resources Information Center

Keys, Tran D.; Farkas, George; Burchinal, Margaret R.; Duncan, Greg J.; Vandell, Deborah L.; Li, Weilin; Ruzek, Erik A.; Howes, Carollee

2013-01-01

This article examines associations between observed quality in preschool center classrooms for approximately 6,250 three- to five-year-olds and their school readiness skills at kindergarten entry. Secondary analyses were conducted using data from four large-scale studies to estimate the effects of preschool center quality and interactions between…

Keeping Teachers in the Center: A Framework of Data-Driven Decision-Making

ERIC Educational Resources Information Center

Light, Daniel; Wexler, Dara H.; Heinze, Juliette

2004-01-01

The Education Development Center's Center for Children and Technology (CCT) conducted a three year study of a large-scale data reporting system, developed by the Grow Network for New York City's Department of Education. This paper presents a framework based on two years of research exploring the intersection of decision-support technologies,…

NOAA's world-class weather and climate prediction center opens at

Science.gov Websites

StumbleUpon Digg More Destinations NOAA's world-class weather and climate prediction center opens at currents and large-scale rain and snow storms. Billions of earth observations from around the world flow operations. Investing in this center is an investment in our human capital, serving as a world class facility

The Relationship Between Galaxies and the Large-Scale Structure of the Universe

NASA Astrophysics Data System (ADS)

Coil, Alison L.

2018-06-01

I will describe our current understanding of the relationship between galaxies and the large-scale structure of the Universe, often called the galaxy-halo connection. Galaxies are thought to form and evolve in the centers of dark matter halos, which grow along with the galaxies they host. Large galaxy redshift surveys have revealed clear observational signatures of connections between galaxy properties and their clustering properties on large scales. For example, older, quiescent galaxies are known to cluster more strongly than younger, star-forming galaxies, which are more likely to be found in galactic voids and filaments rather than the centers of galaxy clusters. I will show how cosmological numerical simulations have aided our understanding of this galaxy-halo connection and what is known from a statistical point of view about how galaxies populate dark matter halos. This knowledge both helps us learn about galaxy evolution and is fundamental to our ability to use galaxy surveys to reveal cosmological information. I will talk briefly about some of the current open questions in the field, including galactic conformity and assembly bias.

Template Interfaces for Agile Parallel Data-Intensive Science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramakrishnan, Lavanya; Gunter, Daniel; Pastorello, Gilerto Z.

Tigres provides a programming library to compose and execute large-scale data-intensive scientific workflows from desktops to supercomputers. DOE User Facilities and large science collaborations are increasingly generating large enough data sets that it is no longer practical to download them to a desktop to operate on them. They are instead stored at centralized compute and storage resources such as high performance computing (HPC) centers. Analysis of this data requires an ability to run on these facilities, but with current technologies, scaling an analysis to an HPC center and to a large data set is difficult even for experts. Tigres ismore » addressing the challenge of enabling collaborative analysis of DOE Science data through a new concept of reusable "templates" that enable scientists to easily compose, run and manage collaborative computational tasks. These templates define common computation patterns used in analyzing a data set.« less

Measuring large scale space perception in literary texts

NASA Astrophysics Data System (ADS)

Rossi, Paolo

2007-07-01

A center and radius of “perception” (in the sense of environmental cognition) can be formally associated with a written text and operationally defined. Simple algorithms for their computation are presented, and indicators for anisotropy in large scale space perception are introduced. The relevance of these notions for the analysis of literary and historical records is briefly discussed and illustrated with an example taken from medieval historiography.

Research-Based Recommendations for the Use of Accommodations in Large-Scale Assessments: 2012 Update. Practical Guidelines for the Education of English Language Learners. Book 4

ERIC Educational Resources Information Center

Kieffer, Michael J.; Rivera, Mabel; Francis, David J.

2012-01-01

This report presents results from a new quantitative synthesis of research on the effectiveness and validity of test accommodations for English language learners (ELLs) taking large-scale assessments. In 2006, the Center on Instruction published a review of the literature on test accommodations for ELLs titled "Practical Guidelines for the…

Modeling relief demands in an emergency supply chain system under large-scale disasters based on a queuing network.

PubMed

He, Xinhua; Hu, Wenfa

2014-01-01

This paper presents a multiple-rescue model for an emergency supply chain system under uncertainties in large-scale affected area of disasters. The proposed methodology takes into consideration that the rescue demands caused by a large-scale disaster are scattered in several locations; the servers are arranged in multiple echelons (resource depots, distribution centers, and rescue center sites) located in different places but are coordinated within one emergency supply chain system; depending on the types of rescue demands, one or more distinct servers dispatch emergency resources in different vehicle routes, and emergency rescue services queue in multiple rescue-demand locations. This emergency system is modeled as a minimal queuing response time model of location and allocation. A solution to this complex mathematical problem is developed based on genetic algorithm. Finally, a case study of an emergency supply chain system operating in Shanghai is discussed. The results demonstrate the robustness and applicability of the proposed model.

Modeling Relief Demands in an Emergency Supply Chain System under Large-Scale Disasters Based on a Queuing Network

PubMed Central

He, Xinhua

2014-01-01

This paper presents a multiple-rescue model for an emergency supply chain system under uncertainties in large-scale affected area of disasters. The proposed methodology takes into consideration that the rescue demands caused by a large-scale disaster are scattered in several locations; the servers are arranged in multiple echelons (resource depots, distribution centers, and rescue center sites) located in different places but are coordinated within one emergency supply chain system; depending on the types of rescue demands, one or more distinct servers dispatch emergency resources in different vehicle routes, and emergency rescue services queue in multiple rescue-demand locations. This emergency system is modeled as a minimal queuing response time model of location and allocation. A solution to this complex mathematical problem is developed based on genetic algorithm. Finally, a case study of an emergency supply chain system operating in Shanghai is discussed. The results demonstrate the robustness and applicability of the proposed model. PMID:24688367

A Dialogue with Carl Rogers: Cross-Cultural Challenges of Facilitating Person-Centered Groups in Africa.

ERIC Educational Resources Information Center

Hain-Hill, Alicia; Rogers, Carl R.

1988-01-01

Presents brainstorming dialogue with Carl Rogers which was held in January of 1987, shortly before Rogers's death. Explores basic challenges involved in a large-scale, cross-cultural application of person-centered group work in South Africa. (Author)

Photogrammetric Technique for Center of Gravity Determination

NASA Technical Reports Server (NTRS)

Jones, Thomas W.; Johnson, Thomas H.; Shemwell, Dave; Shreves, Christopher M.

2012-01-01

A new measurement technique for determination of the center of gravity (CG) for large scale objects has been demonstrated. The experimental method was conducted as part of an LS-DYNA model validation program for the Max Launch Abort System (MLAS) crew module. The test was conducted on the full scale crew module concept at NASA Langley Research Center. Multi-camera photogrammetry was used to measure the test article in several asymmetric configurations. The objective of these measurements was to provide validation of the CG as computed from the original mechanical design. The methodology, measurement technique, and measurement results are presented.

The Mothball, Sustainment, and Proposed Reactivation of the Hypersonic Tunnel Facility (HTF) at NASA Glenn Research Center Plum Brook Station

NASA Technical Reports Server (NTRS)

Thomas, Scott R.; Lee, Jinho; Stephens, John W.; Hostler, Robert W., Jr.; VonKamp, William D.

2010-01-01

The Hypersonic Tunnel Facility (HTF) located at the NASA Glenn Research Center s Plum Brook Station in Sandusky, Ohio, is the nation s only large-scale, non-vitiated, hypersonic propulsion test facility. The HTF, with its 4-story graphite induction heater, is capable of duplicating Mach 5, 6, and 7 flight conditions. This unique propulsion system test facility has experienced several standby and reactivation cycles. The intent of the paper is to overview the HTF capabilities to the propulsion community, present the current status of HTF, and share the lessons learned from putting a large-scale facility into mothball status for a later restart

Hydroclimatic variability in the Lake Mondsee region and its relationships with large-scale climate anomaly patterns

NASA Astrophysics Data System (ADS)

Rimbu, Norel; Ionita, Monica; Swierczynski, Tina; Brauer, Achim; Kämpf, Lucas; Czymzik, Markus

2017-04-01

Flood triggered detrital layers in varved sediments of Lake Mondsee, located at the northern fringe of the European Alps (47°48'N,13°23'E), provide an important archive of regional hydroclimatic variability during the mid- to late Holocene. To improve the interpretation of the flood layer record in terms of large-scale climate variability, we investigate the relationships between observational hydrological records from the region, like the Mondsee lake level, the runoff of the lake's main inflow Griesler Ache, with observed precipitation and global climate patterns. The lake level shows a strong positive linear trend during the observational period in all seasons. Additionally, lake level presents important interannual to multidecadal variations. These variations are associated with distinct seasonal atmospheric circulation patterns. A pronounced anomalous anticyclonic center over the Iberian Peninsula is associated with high lake levels values during winter. This center moves southwestward during spring, summer and autumn. In the same time, a cyclonic anomaly center is recorded over central and western Europe. This anomalous circulation extends southwestward from winter to autumn. Similar atmospheric circulation patterns are associated with river runoff and precipitation variability from the region. High lake levels are associated with positive local precipitation anomalies in all seasons as well as with negative local temperature anomalies during spring, summer and autumn. A correlation analysis reveals that lake level, runoff and precipitation variability is related to large-scale sea surface temperature anomaly patterns in all seasons suggesting a possible impact of large-scale climatic modes, like the North Atlantic Oscillation and Atlantic Multidecadal Oscillation on hydroclimatic variability in the Lake Mondsee region. The results presented in this study can be used for a more robust interpretation of the long flood layer record from Lake Mondsee sediments in terms of regional and large-scale climate variability during the past.

High-Performance Computing Unlocks Innovation at NREL - Video Text Version

Science.gov Websites

scales, data visualizations and large-scale modeling provide insights and test new ideas. But this type most energy-efficient data center in the world. NREL and Hewlett-Packard won an R&D 100 award-the

High Fidelity Simulations of Large-Scale Wireless Networks (Plus-Up)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Onunkwo, Uzoma

Sandia has built a strong reputation in scalable network simulation and emulation for cyber security studies to protect our nation’s critical information infrastructures. Georgia Tech has preeminent reputation in academia for excellence in scalable discrete event simulations, with strong emphasis on simulating cyber networks. Many of the experts in this field, such as Dr. Richard Fujimoto, Dr. George Riley, and Dr. Chris Carothers, have strong affiliations with Georgia Tech. The collaborative relationship that we intend to immediately pursue is in high fidelity simulations of practical large-scale wireless networks using ns-3 simulator via Dr. George Riley. This project will have mutualmore » benefits in bolstering both institutions’ expertise and reputation in the field of scalable simulation for cyber-security studies. This project promises to address high fidelity simulations of large-scale wireless networks. This proposed collaboration is directly in line with Georgia Tech’s goals for developing and expanding the Communications Systems Center, the Georgia Tech Broadband Institute, and Georgia Tech Information Security Center along with its yearly Emerging Cyber Threats Report. At Sandia, this work benefits the defense systems and assessment area with promise for large-scale assessment of cyber security needs and vulnerabilities of our nation’s critical cyber infrastructures exposed to wireless communications.« less

Propulsion simulator for magnetically-suspended wind tunnel models

NASA Technical Reports Server (NTRS)

Joshi, Prakash B.; Goldey, C. L.; Sacco, G. P.; Lawing, Pierce L.

1991-01-01

The objective of phase two of a current investigation sponsored by NASA Langley Research Center is to demonstrate the measurement of aerodynamic forces/moments, including the effects of exhaust gases, in magnetic suspension and balance system (MSBS) wind tunnels. Two propulsion simulator models are being developed: a small-scale and a large-scale unit, both employing compressed, liquified carbon dioxide as propellant. The small-scale unit was designed, fabricated, and statically-tested at Physical Sciences Inc. (PSI). The large-scale simulator is currently in the preliminary design stage. The small-scale simulator design/development is presented, and the data from its static firing on a thrust stand are discussed. The analysis of this data provides important information for the design of the large-scale unit. A description of the preliminary design of the device is also presented.

The large-scale distribution of galaxies

NASA Technical Reports Server (NTRS)

Geller, Margaret J.

1989-01-01

The spatial distribution of galaxies in the universe is characterized on the basis of the six completed strips of the Harvard-Smithsonian Center for Astrophysics redshift-survey extension. The design of the survey is briefly reviewed, and the results are presented graphically. Vast low-density voids similar to the void in Bootes are found, almost completely surrounded by thin sheets of galaxies. Also discussed are the implications of the results for the survey sampling problem, the two-point correlation function of the galaxy distribution, the possibility of detecting large-scale coherent flows, theoretical models of large-scale structure, and the identification of groups and clusters of galaxies.

Measuring the efficiency of dental departments in medical centers: a nonparametric analysis approach.

PubMed

Wang, Su-Chen; Tsai, Chi-Cheng; Huang, Shun-Te; Hong, Yu-Jue

2002-12-01

Data envelopment analysis (DEA), a cross-sectional study design based on secondary data analysis, was used to evaluate the relative operational efficiency of 16 dental departments in medical centers in Taiwan in 1999. The results indicated that 68.7% of all dental departments in medical centers had poor performance in terms of overall efficiency and scale efficiency. All relatively efficient dental departments were in private medical centers. Half of these dental departments were unable to fully utilize available medical resources. 75.0% of public medical centers did not take full advantage of medical resources at their disposal. In the returns to scale, 56.3% of dental departments in medical centers exhibited increasing returns to scale, due to the insufficient scale influencing overall hospital operational efficiency. Public medical centers accounted for 77.8% of the institutions affected. The scale of dental departments in private medical centers was more appropriate than those in public medical centers. In the sensitivity analysis, the numbers of residents, interns, and published papers were used to assess teaching and research. Greater emphasis on teaching and research in medical centers has a large effect on the relative inefficiency of hospital operation. Dental departments in private medical centers had a higher mean overall efficiency score than those in public medical centers, and the overall efficiency of dental departments in non-university hospitals was greater than those in university hospitals. There was no information to evaluate the long-term efficiency of each dental department in all hospitals. A different combination of input and output variables, using common multipliers for efficiency value measurements in DEA, may help establish different pioneering dental departments in hospitals.

The MMPI-2 Symptom Validity Scale (FBS) Not Influenced by Medical Impairment: A Large Sleep Center Investigation

ERIC Educational Resources Information Center

Greiffenstein, Manfred F.

2010-01-01

The Symptom Validity Scale (Minnesota Multiphasic Personality Inventory-2-FBS [MMPI-2-FBS]) is a standard MMPI-2 validity scale measuring overstatement of somatic distress and subjective disability. Some critics assert the MMPI-2-FBS misclassifies too many medically impaired persons as malingering symptoms. This study tests the assertion of…

The two-point correlation function for groups of galaxies in the Center for Astrophysics redshift survey

NASA Technical Reports Server (NTRS)

Ramella, Massimo; Geller, Margaret J.; Huchra, John P.

1990-01-01

The large-scale distribution of groups of galaxies selected from complete slices of the CfA redshift survey extension is examined. The survey is used to reexamine the contribution of group members to the galaxy correlation function. The relationship between the correlation function for groups and those calculated for rich clusters is discussed, and the results for groups are examined as an extension of the relation between correlation function amplitude and richness. The group correlation function indicates that groups and individual galaxies are equivalent tracers of the large-scale matter distribution. The distribution of group centers is equivalent to random sampling of the galaxy distribution. The amplitude of the correlation function for groups is consistent with an extrapolation of the amplitude-richness relation for clusters. The amplitude scaled by the mean intersystem separation is also consistent with results for richer clusters.

The Effect of Student-Centered Approaches on Students' Interest and Achievement in Science: Relevant Topic-Based, Open and Guided Inquiry-Based, and Discussion-Based Approaches

NASA Astrophysics Data System (ADS)

Kang, Jingoo; Keinonen, Tuula

2017-04-01

Since students have lost their interest in school science, several student-centered approaches, such as using topics that are relevant for students, inquiry-based learning, and discussion-based learning have been implemented to attract pupils into science. However, the effect of these approaches was usually measured in small-scale research, and thus, the large-scale evidence supporting student-centered approaches in general use is insufficient. Accordingly, this study aimed to investigate the effect of student-centered approaches on students' interest and achievement by analyzing a large-scale data set derived from Program for International Student Assessment (PISA) 2006, to add evidence for advocating these approaches in school science, and to generalize the effects on a large population. We used Finnish PISA 2006 data, which is the most recent data that measures science literacy and that contains relevant variables for the constructs of this study. As a consequence of the factor analyses, four teaching methods were grouped as student-centered approaches (relevant topic-based, open and guided inquiry-based, and discussion-based approaches in school science) from the Finnish PISA 2006 sample. The structural equation modeling result indicated that using topics relevant for students positively affected students' interest and achievement in science. Guided inquiry-based learning was also indicated as a strong positive predictor for students' achievement, and its effect was also positively associated with students' interest. On the other hand, open inquiry-based learning was indicated as a strong negative predictor for students' achievement, as was using discussion in school science. Implications and limitations of the study were discussed.

Towards Portable Large-Scale Image Processing with High-Performance Computing.

PubMed

Huo, Yuankai; Blaber, Justin; Damon, Stephen M; Boyd, Brian D; Bao, Shunxing; Parvathaneni, Prasanna; Noguera, Camilo Bermudez; Chaganti, Shikha; Nath, Vishwesh; Greer, Jasmine M; Lyu, Ilwoo; French, William R; Newton, Allen T; Rogers, Baxter P; Landman, Bennett A

2018-05-03

High-throughput, large-scale medical image computing demands tight integration of high-performance computing (HPC) infrastructure for data storage, job distribution, and image processing. The Vanderbilt University Institute for Imaging Science (VUIIS) Center for Computational Imaging (CCI) has constructed a large-scale image storage and processing infrastructure that is composed of (1) a large-scale image database using the eXtensible Neuroimaging Archive Toolkit (XNAT), (2) a content-aware job scheduling platform using the Distributed Automation for XNAT pipeline automation tool (DAX), and (3) a wide variety of encapsulated image processing pipelines called "spiders." The VUIIS CCI medical image data storage and processing infrastructure have housed and processed nearly half-million medical image volumes with Vanderbilt Advanced Computing Center for Research and Education (ACCRE), which is the HPC facility at the Vanderbilt University. The initial deployment was natively deployed (i.e., direct installations on a bare-metal server) within the ACCRE hardware and software environments, which lead to issues of portability and sustainability. First, it could be laborious to deploy the entire VUIIS CCI medical image data storage and processing infrastructure to another HPC center with varying hardware infrastructure, library availability, and software permission policies. Second, the spiders were not developed in an isolated manner, which has led to software dependency issues during system upgrades or remote software installation. To address such issues, herein, we describe recent innovations using containerization techniques with XNAT/DAX which are used to isolate the VUIIS CCI medical image data storage and processing infrastructure from the underlying hardware and software environments. The newly presented XNAT/DAX solution has the following new features: (1) multi-level portability from system level to the application level, (2) flexible and dynamic software development and expansion, and (3) scalable spider deployment compatible with HPC clusters and local workstations.

Condition Monitoring of Large-Scale Facilities

NASA Technical Reports Server (NTRS)

Hall, David L.

1999-01-01

This document provides a summary of the research conducted for the NASA Ames Research Center under grant NAG2-1182 (Condition-Based Monitoring of Large-Scale Facilities). The information includes copies of view graphs presented at NASA Ames in the final Workshop (held during December of 1998), as well as a copy of a technical report provided to the COTR (Dr. Anne Patterson-Hine) subsequent to the workshop. The material describes the experimental design, collection of data, and analysis results associated with monitoring the health of large-scale facilities. In addition to this material, a copy of the Pennsylvania State University Applied Research Laboratory data fusion visual programming tool kit was also provided to NASA Ames researchers.

Using the ACRL Framework to Develop a Student-Centered Model for Program-Level Assessment

ERIC Educational Resources Information Center

Gammons, Rachel Wilder; Inge, Lindsay Taylor

2017-01-01

Information literacy instruction presents a difficult balance between quantity and quality, particularly for large-scale general education courses. This paper discusses the overhaul of the freshman composition instruction program at the University of Maryland Libraries, focusing on the transition from survey assessments to a student-centered and…

Grant Development for Large Scale Research Proposals: An Overview and Case Study

ERIC Educational Resources Information Center

Goodman, Ira S.

2011-01-01

With some NIH pay lines running at or below the 10th percentile, and funding becoming scarce for large science grants, new approaches are necessary to secure large interdisciplinary grant awards. The UCSD Moores Cancer Center has developed a team approach, starting with the identification of a competitive opportunity and progressing to the…

Influence of Antarctic Oscillation on Intraseasonal Variability of Large-Scale Circulations Over the Western North Pacific

DTIC Science & Technology

2005-03-01

quartiles, and thus locates the central 50% of the data. The center bar through each box represents the persistence median. The whiskers extend away from...level of tropical cyclone activity. Numerous factors (e.g., scarcity of observations over large ocean basins , various scales of motion present in the... central South Indian Ocean, South Pacific Ocean east of New Zealand, and South Atlantic Ocean near the Falkland Islands. The increased pressure gradient

Modeling Change in Large-Scale Longitudinal Studies of Educational Growth: Four Decades of Contributions to the Assessment of Educational Growth. ETC R&D Scientific and Policy Contributions Series. ETS SPC-12-01. Research Report No. RR-12-04

ERIC Educational Resources Information Center

Rock, Donald A.

2012-01-01

This paper provides a history of ETS's role in developing assessment instruments and psychometric procedures for measuring change in large-scale national assessments funded by the Longitudinal Studies branch of the National Center for Education Statistics. It documents the innovations developed during more than 30 years of working with…

Modeling Change in Large-Scale Longitudinal Studies of Educational Growth: Four Decades of Contributions to the Assessment of Educational Growth. Research Report. ETS RR-12-04. ETS R&D Scientific and Policy Contributions Series. ETS SPC-12-01

ERIC Educational Resources Information Center

Rock, Donald A.

2012-01-01

This paper provides a history of ETS's role in developing assessment instruments and psychometric procedures for measuring change in large-scale national assessments funded by the Longitudinal Studies branch of the National Center for Education Statistics. It documents the innovations developed during more than 30 years of working with…

Impact of spectral nudging on the downscaling of tropical cyclones in regional climate simulations

NASA Astrophysics Data System (ADS)

Choi, Suk-Jin; Lee, Dong-Kyou

2016-06-01

This study investigated the simulations of three months of seasonal tropical cyclone (TC) activity over the western North Pacific using the Advanced Research WRF Model. In the control experiment (CTL), the TC frequency was considerably overestimated. Additionally, the tracks of some TCs tended to have larger radii of curvature and were shifted eastward. The large-scale environments of westerly monsoon flows and subtropical Pacific highs were unreasonably simulated. The overestimated frequency of TC formation was attributed to a strengthened westerly wind field in the southern quadrants of the TC center. In comparison with the experiment with the spectral nudging method, the strengthened wind speed was mainly modulated by large-scale flow that was greater than approximately 1000 km in the model domain. The spurious formation and undesirable tracks of TCs in the CTL were considerably improved by reproducing realistic large-scale atmospheric monsoon circulation with substantial adjustment between large-scale flow in the model domain and large-scale boundary forcing modified by the spectral nudging method. The realistic monsoon circulation took a vital role in simulating realistic TCs. It revealed that, in the downscaling from large-scale fields for regional climate simulations, scale interaction between model-generated regional features and forced large-scale fields should be considered, and spectral nudging is a desirable method in the downscaling method.

"Fan-Tip-Drive" High-Power-Density, Permanent Magnet Electric Motor and Test Rig Designed for a Nonpolluting Aircraft Propulsion Program

NASA Technical Reports Server (NTRS)

Brown, Gerald V.; Kascak, Albert F.

2004-01-01

A scaled blade-tip-drive test rig was designed at the NASA Glenn Research Center. The rig is a scaled version of a direct-current brushless motor that would be located in the shroud of a thrust fan. This geometry is very attractive since the allowable speed of the armature is approximately the speed of the blade tips (Mach 1 or 1100 ft/s). The magnetic pressure generated in the motor acts over a large area and, thus, produces a large force or torque. This large force multiplied by the large velocity results in a high-power-density motor.

Dependence of high density nitrogen-vacancy center ensemble coherence on electron irradiation doses and annealing time

NASA Astrophysics Data System (ADS)

Zhang, C.; Yuan, H.; Zhang, N.; Xu, L. X.; Li, B.; Cheng, G. D.; Wang, Y.; Gui, Q.; Fang, J. C.

2017-12-01

Negatively charged nitrogen-vacancy (NV-) center ensembles in diamond have proved to have great potential for use in highly sensitive, small-package solid-state quantum sensors. One way to improve sensitivity is to produce a high-density NV- center ensemble on a large scale with a long coherence lifetime. In this work, the NV- center ensemble is prepared in type-Ib diamond using high energy electron irradiation and annealing, and the transverse relaxation time of the ensemble—T 2—was systematically investigated as a function of the irradiation electron dose and annealing time. Dynamical decoupling sequences were used to characterize T 2. To overcome the problem of low signal-to-noise ratio in T 2 measurement, a coupled strip lines waveguide was used to synchronously manipulate NV- centers along three directions to improve fluorescence signal contrast. Finally, NV- center ensembles with a high concentration of roughly 1015 mm-3 were manipulated within a ~10 µs coherence time. By applying a multi-coupled strip-lines waveguide to improve the effective volume of the diamond, a sub-femtotesla sensitivity for AC field magnetometry can be achieved. The long-coherence high-density large-scale NV- center ensemble in diamond means that types of room-temperature micro-sized solid-state quantum sensors with ultra-high sensitivity can be further developed in the near future.

Clinical Scales Do Not Reliably Identify Acute Ischemic Stroke Patients With Large-Artery Occlusion.

PubMed

Turc, Guillaume; Maïer, Benjamin; Naggara, Olivier; Seners, Pierre; Isabel, Clothilde; Tisserand, Marie; Raynouard, Igor; Edjlali, Myriam; Calvet, David; Baron, Jean-Claude; Mas, Jean-Louis; Oppenheim, Catherine

2016-06-01

It remains debated whether clinical scores can help identify acute ischemic stroke patients with large-artery occlusion and hence improve triage in the era of thrombectomy. We aimed to determine the accuracy of published clinical scores to predict large-artery occlusion. We assessed the performance of 13 clinical scores to predict large-artery occlusion in consecutive patients with acute ischemic stroke undergoing clinical examination and magnetic resonance or computed tomographic angiography ≤6 hours of symptom onset. When no cutoff was published, we used the cutoff maximizing the sum of sensitivity and specificity in our cohort. We also determined, for each score, the cutoff associated with a false-negative rate ≤10%. Of 1004 patients (median National Institute of Health Stroke Scale score, 7; range, 0-40), 328 (32.7%) had an occlusion of the internal carotid artery, M1 segment of the middle cerebral artery, or basilar artery. The highest accuracy (79%; 95% confidence interval, 77-82) was observed for National Institute of Health Stroke Scale score ≥11 and Rapid Arterial Occlusion Evaluation Scale score ≥5. However, these cutoffs were associated with false-negative rates >25%. Cutoffs associated with an false-negative rate ≤10% were 5, 1, and 0 for National Institute of Health Stroke Scale, Rapid Arterial Occlusion Evaluation Scale, and Cincinnati Prehospital Stroke Severity Scale, respectively. Using published cutoffs for triage would result in a loss of opportunity for ≥20% of patients with large-artery occlusion who would be inappropriately sent to a center lacking neurointerventional facilities. Conversely, using cutoffs reducing the false-negative rate to 10% would result in sending almost every patient to a comprehensive stroke center. Our findings, therefore, suggest that intracranial arterial imaging should be performed in all patients with acute ischemic stroke presenting within 6 hours of symptom onset. © 2016 American Heart Association, Inc.

Scaling and Sustaining Effective Early Childhood Programs through School-Family-University Collaboration

ERIC Educational Resources Information Center

Reynolds, Arthur J.; Hayakawa, Momoko; Ou, Suh-Ruu; Mondi, Christina F.; Englund, Michelle M.; Candee, Allyson J.; Smerillo, Nicole E.

2017-01-01

We describe the development, implementation, and evaluation of a comprehensive preschool to third grade prevention program for the goals of sustaining services at a large scale. The Midwest Child-Parent Center (CPC) Expansion is a multilevel collaborative school reform model designed to improve school achievement and parental involvement from ages…

Robust Control of Multivariable and Large Scale Systems.

DTIC Science & Technology

1986-03-14

AD-A175 $5B ROBUST CONTROL OF MULTIVRRIALE AND LARG SCALE SYSTEMS V2 R75 (U) HONEYWELL SYSTEMS AND RESEARCH CENTER MINNEAPOLIS MN J C DOYLE ET AL...ONIJQ 86 R alFS ja ,.AMIECFOEPF:ORMING ORGANIZATION So OFFICE SYMBOL 7a NAME OF MONITORING ORGANIZATI ON jonevwell Systems & Research If 4000c" Air...Force Office of Scientific Research .~ C :AE S C.rv. Stare arma ZIP Code) 7C ADDRESS (Crty. Stare. am ZIP Code, *3660 Marshall Street NE Building 410

Model Analysis of an Aircraft Fueslage Panel using Experimental and Finite-Element Techniques

NASA Technical Reports Server (NTRS)

Fleming, Gary A.; Buehrle, Ralph D.; Storaasli, Olaf L.

1998-01-01

The application of Electro-Optic Holography (EOH) for measuring the center bay vibration modes of an aircraft fuselage panel under forced excitation is presented. The requirement of free-free panel boundary conditions made the acquisition of quantitative EOH data challenging since large scale rigid body motions corrupted measurements of the high frequency vibrations of interest. Image processing routines designed to minimize effects of large scale motions were applied to successfully resurrect quantitative EOH vibrational amplitude measurements

Scale-Up: Improving Large Enrollment Physics Courses

NASA Astrophysics Data System (ADS)

Beichner, Robert

1999-11-01

The Student-Centered Activities for Large Enrollment University Physics (SCALE-UP) project is working to establish a learning environment that will promote increased conceptual understanding, improved problem-solving performance, and greater student satisfaction, while still maintaining class sizes of approximately 100. We are also addressing the new ABET engineering accreditation requirements for inquiry-based learning along with communication and team-oriented skills development. Results of studies of our latest classroom design, plans for future classroom space, and the current iteration of instructional materials will be discussed.

A Three Dimensional Picture of Galactic Center Mass Flows From Kiloparsec to Subparsec Scales

NASA Astrophysics Data System (ADS)

Mills, Elisabeth A.

2018-06-01

The centers of galaxies host extreme and energetic phenomena, from the amassing of incredibly dense reservoirs of gas to nuclear starbursts producing tens to hundreds of solar masses per year to accreting supermassive black holes launching jets. All of these are found on compact scales from hundreds of parsecs to less than a microparsec. The nearest laboratory for examining these processes is the center of our own Milky Way Galaxy. Although the black hole is not currently active and the star formation rate is relatively low, it is still our best opportunity for detailed insight into the processes that regulate the growth of the central supermassive black hole. By providing access to mid and far infrared wavelengths, SOFIA plays a unique role in connecting large and small scales in the Galactic center and studying the cycling of gas through this region. In this talk I will highlight several key open questions and outline the role that SOFIA continues to play in answering them.

On the Relationality of Centers, Peripheries and Interactional Regimes: Translanguaging in a Community Interpreting Event

ERIC Educational Resources Information Center

Baynham, Mike; Hanušová, Jolana

2017-01-01

In this paper we discuss a multilingual interactional event that involves both interpreting and literacy work, part of a large scale study on translanguaging in superdiverse urban settings. In the first part of the interaction, the center/periphery dynamic is played out in what might be called "contested translanguaging" between Standard…

Differences in Access to Care among Students Using School-Based Health Centers

ERIC Educational Resources Information Center

Parasuraman, Sarika Rane; Shi, Leiyu

2015-01-01

Health care reform has changed the landscape for the nation's health safety net, and school-based health centers (SBHCs) remain an important part of this system. However, few large-scale studies have been conducted to assess their impact on access to care. This study investigated differences in access among a nationally representative sample of…

Fluorescent nanodiamonds and their use in biomedical research

NASA Astrophysics Data System (ADS)

Suarez-Kelly, Lorena P.; Rampersaud, Isaac V.; Moritz, Charles E.; Campbell, Amanda R.; Hu, Zhiwei; Alkahtani, Masfer H.; Alghannam, Fahad S.; Hemmer, Phillip; Carson, William E.; Rampersaud, Arfaan A.

2016-03-01

Nanodiamonds containing color-centers produce non-quenching fluorescence that is easily detected. This makes them useful for cellular, proteomic and genomic applications. However, fluorescent nanodiamonds have yet to become popular in the biomedical research community as labeling reagents. We discuss production of nanodiamonds with distinct color-centers and assess their biocompatibility and techniques for bioconjugation. Fluorescent diamonds were fabricated by electron irradiation of high-pressure, high-temperature micron-sized diamonds which generated diamonds with vacancy-related defects (V). These diamonds were annealed to create nitrogen vacancy (NV)-centers then following a milling step were fractionated into nanoparticle sizes of 30, 60, and 95 nm. Optical characterization of Vand NV-center diamonds demonstrated fluorescence in two distinct green and red channels, respectively. In vitro studies demonstrated that these nanodiamonds are biocompatible and readily taken up by murine macrophage cells. Quantification of NV-center nanodiamond uptake by flow cytometry, showed that uptake was independent of nanodiamond size. Confocal microscopy demonstrated that NV-center nanodiamonds accumulate within the cytoplasm of these cells. NV-center nanodiamonds were then conjugated with streptavidin using a short polyethylene chain as linker. Conjugation was confirmed via a catalytic assay employing biotinylated-horseradish peroxidase. We present a technique for large-scale production of biocompatible conjugated V- or NV-center nanodiamonds. Functional testing is essential for standardization of fluorescent nanodiamond bioconjugates and quality control. Large-scale production of bioconjugated fluorescent nanodiamonds is crucial to their development as novel tools for biological and medical applications.

Large-scale solar magnetic fields and H-alpha patterns

NASA Technical Reports Server (NTRS)

Mcintosh, P. S.

1972-01-01

Coronal and interplanetary magnetic fields computed from measurements of large-scale photospheric magnetic fields suffer from interruptions in day-to-day observations and the limitation of using only measurements made near the solar central meridian. Procedures were devised for inferring the lines of polarity reversal from H-alpha solar patrol photographs that map the same large-scale features found on Mt. Wilson magnetograms. These features may be monitored without interruption by combining observations from the global network of observatories associated with NOAA's Space Environment Services Center. The patterns of inferred magnetic fields may be followed accurately as far as 60 deg from central meridian. Such patterns will be used to improve predictions of coronal features during the next solar eclipse.

Development of Dynamic Flow Field Pressure Probes Suitable for Use in Large Scale Supersonic Wind Tunnels

NASA Technical Reports Server (NTRS)

Porro, A. Robert

2000-01-01

A series of dynamic flow field pressure probes were developed for use in large-scale supersonic wind tunnels at NASA Glenn Research Center. These flow field probes include pitot, static, and five-hole conical pressure probes that are capable of capturing fast acting flow field pressure transients that occur on a millisecond time scale. The pitot and static probes can be used to determine local Mach number time histories during a transient event. The five-hole conical pressure probes are used primarily to determine local flow angularity, but can also determine local Mach number. These probes were designed, developed, and tested at the NASA Glenn Research Center. They were also used in a NASA Glenn 10-by 10-Foot Supersonic Wind Tunnel (SWT) test program where they successfully acquired flow field pressure data in the vicinity of a propulsion system during an engine compressor staff and inlet unstart transient event. Details of the design, development, and subsequent use of these probes are discussed in this report.

Iterative User-Centered Design of a Next Generation Patient Monitoring System for Emergency Medical Response

PubMed Central

Gao, Tia; Kim, Matthew I.; White, David; Alm, Alexander M.

2006-01-01

We have developed a system for real-time patient monitoring during large-scale disasters. Our system is designed with scalable algorithms to monitor large numbers of patients, an intuitive interface to support the overwhelmed responders, and ad-hoc mesh networking capabilities to maintain connectivity to patients in the chaotic settings. This paper describes an iterative approach to user-centered design adopted to guide development of our system. This system is a part of the Advanced Health and Disaster Aid Network (AID-N) architecture. PMID:17238348

The mean density and two-point correlation function for the CfA redshift survey slices

NASA Technical Reports Server (NTRS)

De Lapparent, Valerie; Geller, Margaret J.; Huchra, John P.

1988-01-01

The effect of large-scale inhomogeneities on the determination of the mean number density and the two-point spatial correlation function were investigated for two complete slices of the extension of the Center for Astrophysics (CfA) redshift survey (de Lapparent et al., 1986). It was found that the mean galaxy number density for the two strips is uncertain by 25 percent, more so than previously estimated. The large uncertainty in the mean density introduces substantial uncertainty in the determination of the two-point correlation function, particularly at large scale; thus, for the 12-deg slice of the CfA redshift survey, the amplitude of the correlation function at intermediate scales is uncertain by a factor of 2. The large uncertainties in the correlation functions might reflect the lack of a fair sample.

Spatial and Temporal scales of time-averaged 700 MB height anomalies

NASA Technical Reports Server (NTRS)

Gutzler, D.

1981-01-01

The monthly and seasonal forecasting technique is based to a large extent on the extrapolation of trends in the positions of the centers of time averaged geopotential height anomalies. The complete forecasted height pattern is subsequently drawn around the forecasted anomaly centers. The efficacy of this technique was tested and time series of observed monthly mean and 5 day mean 700 mb geopotential heights were examined. Autocorrelation statistics are generated to document the tendency for persistence of anomalies. These statistics are compared to a red noise hypothesis to check for evidence of possible preferred time scales of persistence. Space-time spectral analyses at middle latitudes are checked for evidence of periodicities which could be associated with predictable month-to-month trends. A local measure of the average spatial scale of anomalies is devised for guidance in the completion of the anomaly pattern around the forecasted centers.

US EPA - ToxCast and the Tox21 program: perspectives

EPA Science Inventory

ToxCast is a large-scale project being conducted by the U.S. EPA to screen ~2000 chemicals against a large battery of in vitro high-throughput screening (HTS) assays. ToxCast is complemented by the Tox21 project being jointly carried out by the U.S. NIH Chemical Genomics Center (...

Artificial intelligence issues related to automated computing operations

NASA Technical Reports Server (NTRS)

Hornfeck, William A.

1989-01-01

Large data processing installations represent target systems for effective applications of artificial intelligence (AI) constructs. The system organization of a large data processing facility at the NASA Marshall Space Flight Center is presented. The methodology and the issues which are related to AI application to automated operations within a large-scale computing facility are described. Problems to be addressed and initial goals are outlined.

Adjoint-Based Aerodynamic Design of Complex Aerospace Configurations

NASA Technical Reports Server (NTRS)

Nielsen, Eric J.

2016-01-01

An overview of twenty years of adjoint-based aerodynamic design research at NASA Langley Research Center is presented. Adjoint-based algorithms provide a powerful tool for efficient sensitivity analysis of complex large-scale computational fluid dynamics (CFD) simulations. Unlike alternative approaches for which computational expense generally scales with the number of design parameters, adjoint techniques yield sensitivity derivatives of a simulation output with respect to all input parameters at the cost of a single additional simulation. With modern large-scale CFD applications often requiring millions of compute hours for a single analysis, the efficiency afforded by adjoint methods is critical in realizing a computationally tractable design optimization capability for such applications.

Large-scale horizontal flows from SOUP observations of solar granulation

NASA Technical Reports Server (NTRS)

November, L. J.; Simon, G. W.; Tarbell, T. D.; Title, A. M.; Ferguson, S. H.

1987-01-01

Using high resolution time sequence photographs of solar granulation from the SOUP experiment on Spacelab 2, large scale horizontal flows were observed in the solar surface. The measurement method is based upon a local spatial cross correlation analysis. The horizontal motions have amplitudes in the range 300 to 1000 m/s. Radial outflow of granulation from a sunspot penumbra into surrounding photosphere is a striking new discovery. Both the supergranulation pattern and cellular structures having the scale of mesogranulation are seen. The vertical flows that are inferred by continuity of mass from these observed horizontal flows have larger upflow amplitudes in cell centers than downflow amplitudes at cell boundaries.

Comparing Validity Evidence of Two ECERS-R Scoring Systems

ERIC Educational Resources Information Center

Zeng, Songtian

2017-01-01

Over 30 states have adopted the Early Childhood Environmental Rating Scale-Revised (ECERS-R) as a component of their program quality assessment systems, but the use of ECERS-R on such a large scale has raised important questions about implementation. One of the most pressing question centers upon decisions users must make between two scoring…

Interprofessional transformation of clinical education: The first six years of the Veterans Affairs Centers of Excellence in Primary Care Education.

PubMed

Harada, Nancy D; Traylor, Laural; Rugen, Kathryn Wirtz; Bowen, Judith L; Smith, C Scott; Felker, Bradford; Ludke, Deborah; Tonnu-Mihara, Ivy; Ruberg, Joshua L; Adler, Jayson; Uhl, Kimberly; Gardner, Annette L; Gilman, Stuart C

2018-02-20

This paper describes the Centers of Excellence in Primary Care Education (CoEPCE), a seven-site collaborative project funded by the Office of Academic Affiliations (OAA) within the Veterans Health Administration of the United States Department of Veterans Affairs (VA). The CoEPCE was established to fulfill OAA's vision of large-scale transformation of the clinical learning environment within VA primary care settings. This was accomplished by funding new Centers within VA facilities to develop models of interprofessional education (IPE) to teach health professions trainees to deliver high quality interprofessional team-based primary care to Veterans. Using reports and data collected and maintained by the National Coordinating Center over the first six years of the project, we describe program inputs, the multicomponent intervention, activities undertaken to develop the intervention, and short-term outcomes. The findings have implications for lessons learned that can be considered by others seeking large-scale transformation of education within the clinical workplace and the development of interprofessional clinical learning environments. Within the VA, the CoEPCE has laid the foundation for IPE and collaborative practice, but much work remains to disseminate this work throughout the national VA system.

Implementation of Fiber Optic Sensing System on Sandwich Composite Cylinder Buckling Test

NASA Technical Reports Server (NTRS)

Pena, Francisco; Richards, W. Lance; Parker, Allen R.; Piazza, Anthony; Schultz, Marc R.; Rudd, Michelle T.; Gardner, Nathaniel W.; Hilburger, Mark W.

2018-01-01

The National Aeronautics and Space Administration (NASA) Engineering and Safety Center Shell Buckling Knockdown Factor Project is a multicenter project tasked with developing new analysis-based shell buckling design guidelines and design factors (i.e., knockdown factors) through high-fidelity buckling simulations and advanced test technologies. To validate these new buckling knockdown factors for future launch vehicles, the Shell Buckling Knockdown Factor Project is carrying out structural testing on a series of large-scale metallic and composite cylindrical shells at the NASA Marshall Space Flight Center (Marshall Space Flight Center, Alabama). A fiber optic sensor system was used to measure strain on a large-scale sandwich composite cylinder that was tested under multiple axial compressive loads up to more than 850,000 lb, and equivalent bending loads over 22 million in-lb. During the structural testing of the composite cylinder, strain data were collected from optical cables containing distributed fiber Bragg gratings using a custom fiber optic sensor system interrogator developed at the NASA Armstrong Flight Research Center. A total of 16 fiber-optic strands, each containing nearly 1,000 fiber Bragg gratings, measuring strain, were installed on the inner and outer cylinder surfaces to monitor the test article global structural response through high-density real-time and post test strain measurements. The distributed sensing system provided evidence of local epoxy failure at the attachment-ring-to-barrel interface that would not have been detected with conventional instrumentation. Results from the fiber optic sensor system were used to further refine and validate structural models for buckling of the large-scale composite structures. This paper discusses the techniques employed for real-time structural monitoring of the composite cylinder for structural load introduction and distributed bending-strain measurements over a large section of the cylinder by utilizing unique sensing capabilities of fiber optic sensors.

Climatic Consequences of a Large-Scale Desertification in Northeast Brazil: A GCM Simulation Study.

NASA Astrophysics Data System (ADS)

Oyama, Marcos Daisuke; Nobre, Carlos Afonso

2004-08-01

The climatic impacts of a large-scale desertification in northeast Brazil (NEB) are assessed by using the Center for Weather Forecasting and Climate Studies Center for Ocean Land Atmosphere Studies (CPTEC COLA) AGCM. Two numerical runs are performed. In the control run, NEB is covered by its natural vegetation (most of NEB is covered by a xeromorphic vegetation known as caatinga); in the desertification run, NEB vegetation is changed to desert (bare soil). Each run consists of five 1-yr numerical integrations. The results for NEB wet season (March May) are analyzed. Desertification results in hydrological cycle weakening: precipitation, evapotranspiration, moisture convergence, and runoff decrease. Surface net radiation decreases and this reduction is almost evenly divided between sensible and latent heat flux. Atmospheric diabatic heating decreases and subsidence anomalies confined at lower atmospheric levels are found. The climatic impacts result from the cooperative action of feedback processes related to albedo increase, plant transpiration suppression, and roughness length decrease. On a larger scale, desertification leads to precipitation increase in the oceanic belt close to the northernmost part of NEB (NNEB). In the NEB NNEB dipole, the anomalies of vertical motion and atmospheric circulation are confined to lower atmospheric levels, that is, 850 700 hPa. At these levels, circulation anomalies resemble the linear baroclinic response of a shallow atmospheric layer (850 700 hPa) to a tropical heat sink placed over NEB at the middle-layer level. Therefore, NEB climate does show sensitivity to a vegetation change to desert. The present work shows the possibility of significant and pronounced climate impacts, on both regional and large scales, if the environmental degradation in NEB continues unchecked.

DISRUPTION OF LARGE-SCALE NEURAL NETWORKS IN NON-FLUENT/AGRAMMATIC VARIANT PRIMARY PROGRESSIVE APHASIA ASSOCIATED WITH FRONTOTEMPORAL DEGENERATION PATHOLOGY

PubMed Central

Grossman, Murray; Powers, John; Ash, Sherry; McMillan, Corey; Burkholder, Lisa; Irwin, David; Trojanowski, John Q.

2012-01-01

Non-fluent/agrammatic primary progressive aphasia (naPPA) is a progressive neurodegenerative condition most prominently associated with slowed, effortful speech. A clinical imaging marker of naPPA is disease centered in the left inferior frontal lobe. We used multimodal imaging to assess large-scale neural networks underlying effortful expression in 15 patients with sporadic naPPA due to frontotemporal lobar degeneration (FTLD) spectrum pathology. Effortful speech in these patients is related in part to impaired grammatical processing, and to phonologic speech errors. Gray matter (GM) imaging shows frontal and anterior-superior temporal atrophy, most prominently in the left hemisphere. Diffusion tensor imaging reveals reduced fractional anisotropy in several white matter (WM) tracts mediating projections between left frontal and other GM regions. Regression analyses suggest disruption of three large-scale GM-WM neural networks in naPPA that support fluent, grammatical expression. These findings emphasize the role of large-scale neural networks in language, and demonstrate associated language deficits in naPPA. PMID:23218686

Friction Stir Welding of Large Scale Cryogenic Tanks for Aerospace Applications

NASA Technical Reports Server (NTRS)

Russell, Carolyn; Ding, R. Jeffrey

1998-01-01

The Marshall Space Flight Center (MSFC) has established a facility for the joining of large-scale aluminum cryogenic propellant tanks using the friction stir welding process. Longitudinal welds, approximately five meters in length, have been made by retrofitting an existing vertical fusion weld system, designed to fabricate tank barrel sections ranging from two to ten meters in diameter. The structural design requirements of the tooling, clamping and travel system will be described in this presentation along with process controls and real-time data acquisition developed for this application. The approach to retrofitting other large welding tools at MSFC with the friction stir welding process will also be discussed.

CD-ROM technology at the EROS data center

USGS Publications Warehouse

Madigan, Michael E.; Weinheimer, Mary C.

1993-01-01

The vast amount of digital spatial data often required by a single user has created a demand for media alternatives to 1/2" magnetic tape. One such medium that has been recently adopted at the U.S. Geological Survey's EROS Data Center is the compact disc (CD). CD's are a versatile, dynamic, and low-cost method for providing a variety of data on a single media device and are compatible with various computer platforms. CD drives are available for personal computers, UNIX workstations, and mainframe systems, either directly connected, or through a network. This medium furnishes a quick method of reproducing and distributing large amounts of data on a single CD. Several data sets are already available on CD's, including collections of historical Landsat multispectral scanner data and biweekly composites of Advanced Very High Resolution Radiometer data for the conterminous United States. The EROS Data Center intends to provide even more data sets on CD's. Plans include specific data sets on a customized disc to fulfill individual requests, and mass production of unique data sets for large-scale distribution. Requests for a single compact disc-read only memory (CD-ROM) containing a large volume of data either for archiving or for one-time distribution can be addressed with a CD-write once (CD-WO) unit. Mass production and large-scale distribution will require CD-ROM replication and mastering.

Electricity's Future: The Shift to Efficiency and Small-Scale Power. Worldwatch Paper 61.

ERIC Educational Resources Information Center

Flavin, Christopher

Electricity, which has largely supplanted oil as the most controversial energy issue of the 1980s, is at the center of some of the world's bitterest economic and environmental controversies. Soaring costs, high interest rates, and environmental damage caused by large power plants have wreaked havoc on the once booming electricity industry.…

Landscape scale attributes of elk centers of activity in the central Black Hills of South Dakota

Treesearch

Cynthia H. Stubblefield; Kerri T. Vierling; Mark A. Rumble

2006-01-01

We researched the environmental attributes (n = 28) associated with elk (n = 50) summer range (1 May ­30 Sep) in the central Black Hills of South Dakota, USA, during 1998-­2001. We defined high-use areas or centers of activity as landscapes underlying large concentrations of elk locations resulting from the shared fidelity of...

Contruction worker profile. community report--Center, North Dakota

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chalmers, J.A.; Glazner, J.

Center, North Dakota is one of the currently affected communities included in the study to help us learn something of the effects which large-scale construction projects have on small communities. The findings of the Project Survey, which was conducted at the Milton R. Young and Leland Olds Power plants, along with the findings of the Household Survey and the Community Survey, are presented.

Improved Calibration Shows Images True Colors

NASA Technical Reports Server (NTRS)

2015-01-01

Innovative Imaging and Research, located at Stennis Space Center, used a single SBIR contract with the center to build a large-scale integrating sphere, capable of calibrating a whole array of cameras simultaneously, at a fraction of the usual cost for such a device. Through the use of LEDs, the company also made the sphere far more efficient than existing products and able to mimic sunlight.

Evaluating Introductory Physics Classes in Light of the ABET Criteria: An Example from the SCALE-UP Project.

ERIC Educational Resources Information Center

Saul, Jeffery M.; Deardorff, Duane L.; Abbott, David S.; Allain, Rhett J.; Beichner, Robert J.

The Student-Centered Activities for Large Enrollment University Physics (SCALE-UP) project at North Carolina State University (NCSU) is developing a curriculum to promote learning through in-class group activities in introductory physics classes up to 100 students. The authors are currently in Phase II of the project using a specially designed…

Mach Number effects on turbulent superstructures in wall bounded flows

NASA Astrophysics Data System (ADS)

Kaehler, Christian J.; Bross, Matthew; Scharnowski, Sven

2017-11-01

Planer and three-dimensional flow field measurements along a flat plat boundary layer in the Trisonic Wind Tunnel Munich (TWM) are examined with the aim to characterize the scaling, spatial organization, and topology of large scale turbulent superstructures in compressible flow. This facility is ideal for this investigation as the ratio of boundary layer thickness to test section spanwise extent ratio is around 1/25, ensuring minimal sidewall and corner effects on turbulent structures in the center of the test section. A major difficulty in the experimental investigation of large scale features is the mutual size of the superstructures which can extend over many boundary layer thicknesses. Using multiple PIV systems, it was possible to capture the full spatial extent of large-scale structures over a range of Mach numbers from Ma = 0.3 - 3. To calculate the average large-scale structure length and spacing, the acquired vector fields were analyzed by statistical multi-point methods that show large scale structures with a correlation length of around 10 boundary layer thicknesses over the range of Mach numbers investigated. Furthermore, the average spacing between high and low momentum structures is on the order of a boundary layer thicknesses. This work is supported by the Priority Programme SPP 1881 Turbulent Superstructures of the Deutsche Forschungsgemeinschaft.

Scale-Up Method for the Shock Compaction of Powders

NASA Astrophysics Data System (ADS)

Carton, E. P.; Stuivinga, M.

2004-07-01

Shock wave compaction in the cylindrical configuration lends itself to be scaled-up for small-scale industrial applications. While scaling up in the axial direction is easy, scaling up in the lateral direction is less straightforward and may lead to cracks in the center. A different scale up method is presented here; aluminum tubes are filled with the powder to be compacted and placed in a circle inside a large metal tube, with a metal shock wave reflector in the center. The space in between is filled with an inert powder medium: alumina, salt or sand. It is found that salt is the best medium for the integrity of the aluminum tube and for the ease of removal of the aluminum tube out of the (densified) powder medium. Experimental results of (slightly ellipsoidal) shock compacted tubes that are produced this way are shown as an example. In the case of B4C, after infiltration with the aluminum of the tube, fully dense cermet compacts without any cracks are thus produced, batch by batch.

Ballast degradation characterized through triaxial test : research results.

DOT National Transportation Integrated Search

2016-06-01

Transportation Technology Center, Inc. (TTCI) : has supported the development of a large-scale : triaxial test device (Figure 1) for testing ballast : size aggregate materials at the University of : Illinois at Urbana-Champaign (UIUC). This new : tes...

The NASA Glen Research Center's Hypersonic Tunnel Facility. Chapter 16

NASA Technical Reports Server (NTRS)

Woike, Mark R.; Willis, Brian P.

2001-01-01

The NASA Glenn Research Center's Hypersonic Tunnel Facility (HTF) is a blow-down, freejet wind tunnel that provides true enthalpy flight conditions for Mach numbers of 5, 6, and 7. The Hypersonic Tunnel Facility is unique due to its large scale and use of non-vitiated (clean air) flow. A 3MW graphite core storage heater is used to heat the test medium of gaseous nitrogen to the high stagnation temperatures required to produce true enthalpy conditions. Gaseous oxygen is mixed into the heated test flow to generate the true air simulation. The freejet test section is 1.07m (42 in.) in diameter and 4.3m (14 ft) in length. The facility is well suited for the testing of large scale airbreathing propulsion systems. In this chapter, a brief history and detailed description of the facility are presented along with a discussion of the facility's application towards hypersonic airbreathing propulsion testing.

A case study of the intraseasonal oscillation traversing the TOGA-COARE LSD. [large-scale domain

NASA Technical Reports Server (NTRS)

Vincent, Dayton G.; Schrage, Jon M.; Sliwinski, L. D.

1993-01-01

The paper presents examination of tree intraseasonal (30-60 day) oscillations (ISOs) that occurred during the southern summer season (December 1, 1985 - February 28, 1986) traversing the Large-Scale Domain (LSD) TOGA-COARE, the region which also plays an important role in ENSO, Australian monsoon, and extratropical circulations. Data presented include Hovmoeller diagrams of 5-day running means of 250-mb velocity potential anomalies and OLR anomalies; graphs of five-day running means of OLR in precipitable water (W) per sq m, averaged over 10 x 10 deg boxes centered on 5 S and (1) 145 E, (2) 155 E, (3) 165 E, and (4) 165 D, indicating the midpoint of each ISO; and vertical profiles of zonal wind in m/s averaged over the time period that each ISO spends in the 10 x 10 deg box centered at 5 S, and 175 E and 145 E.

Thermophoretically induced large-scale deformations around microscopic heat centers

NASA Astrophysics Data System (ADS)

Puljiz, Mate; Orlishausen, Michael; Köhler, Werner; Menzel, Andreas M.

2016-05-01

Selectively heating a microscopic colloidal particle embedded in a soft elastic matrix is a situation of high practical relevance. For instance, during hyperthermic cancer treatment, cell tissue surrounding heated magnetic colloidal particles is destroyed. Experiments on soft elastic polymeric matrices suggest a very long-ranged, non-decaying radial component of the thermophoretically induced displacement fields around the microscopic heat centers. We theoretically confirm this conjecture using a macroscopic hydrodynamic two-fluid description. Both thermophoretic and elastic effects are included in this theory. Indeed, we find that the elasticity of the environment can cause the experimentally observed large-scale radial displacements in the embedding matrix. Additional experiments confirm the central role of elasticity. Finally, a linearly decaying radial component of the displacement field in the experiments is attributed to the finite size of the experimental sample. Similar results are obtained from our theoretical analysis under modified boundary conditions.

Large-scale horizontal flows from SOUP observations of solar granulation

NASA Astrophysics Data System (ADS)

November, L. J.; Simon, G. W.; Tarbell, T. D.; Title, A. M.; Ferguson, S. H.

1987-09-01

Using high-resolution time-sequence photographs of solar granulation from the SOUP experiment on Spacelab 2 the authors observed large-scale horizontal flows in the solar surface. The measurement method is based upon a local spatial cross correlation analysis. The horizontal motions have amplitudes in the range 300 to 1000 m/s. Radial outflow of granulation from a sunspot penumbra into the surrounding photosphere is a striking new discovery. Both the supergranulation pattern and cellular structures having the scale of mesogranulation are seen. The vertical flows that are inferred by continuity of mass from these observed horizontal flows have larger upflow amplitudes in cell centers than downflow amplitudes at cell boundaries.

Solar Power in Space?

DTIC Science & Technology

2012-01-01

orbit stupendously large orbital power plants—kilometers across—which collect the sun’s raw energy and beam it down to where it is needed on the earth...24-hour, large -scale power to the urban centers where the majority of humanity lives. A network of thousands of solar-power satellites (SPS) could...provide all the power required for an Earth-based population as large as 10 billion people, even for a fully developed “first world” lifestyle but

Regional Climate Simulations over North America: Interaction of Local Processes with Improved Large-Scale Flow.

NASA Astrophysics Data System (ADS)

Miguez-Macho, Gonzalo; Stenchikov, Georgiy L.; Robock, Alan

2005-04-01

The reasons for biases in regional climate simulations were investigated in an attempt to discern whether they arise from deficiencies in the model parameterizations or are due to dynamical problems. Using the Regional Atmospheric Modeling System (RAMS) forced by the National Centers for Environmental Prediction-National Center for Atmospheric Research reanalysis, the detailed climate over North America at 50-km resolution for June 2000 was simulated. First, the RAMS equations were modified to make them applicable to a large region, and its turbulence parameterization was corrected. The initial simulations showed large biases in the location of precipitation patterns and surface air temperatures. By implementing higher-resolution soil data, soil moisture and soil temperature initialization, and corrections to the Kain-Fritch convective scheme, the temperature biases and precipitation amount errors could be removed, but the precipitation location errors remained. The precipitation location biases could only be improved by implementing spectral nudging of the large-scale (wavelength of 2500 km) dynamics in RAMS. This corrected for circulation errors produced by interactions and reflection of the internal domain dynamics with the lateral boundaries where the model was forced by the reanalysis.

Single-domain monoclonal antibodies for the treatment of hepatocellular carcinoma | NCI Technology Transfer Center | TTC

Cancer.gov

The National Cancer Institute seeks parties to license human monoclonal antibodies and immunoconjugates and co-develop, evaluate, and/or commercialize large-scale antibody production and hepatocellular carcinoma (HCC) xenograft mouse models.

The Center for Multiscale Plasma Dynamics, Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gombosi, Tamas I.

The University of Michigan participated in the joint UCLA/Maryland fusion science center focused on plasma physics problems for which the traditional separation of the dynamics into microscale and macroscale processes breaks down. These processes involve large scale flows and magnetic fields tightly coupled to the small scale, kinetic dynamics of turbulence, particle acceleration and energy cascade. The interaction between these vastly disparate scales controls the evolution of the system. The enormous range of temporal and spatial scales associated with these problems renders direct simulation intractable even in computations that use the largest existing parallel computers. Our efforts focused on twomore » main problems: the development of Hall MHD solvers on solution adaptive grids and the development of solution adaptive grids using generalized coordinates so that the proper geometry of inertial confinement can be taken into account and efficient refinement strategies can be obtained.« less

Wind Power Innovation Enables Shift to Utility-Scale - Continuum Magazine

Science.gov Websites

the 1930s, a farmer in South Dakota built a small wind turbine on his farm, generating enough enough electricity to power thousands of homes. Aerial photo of large wind turbine with mountains in the background. Aerial view of the Siemens utility-scale wind turbine at the National Wind Technology Center

Friction-Stir Welding of Large Scale Cryogenic Fuel Tanks for Aerospace Applications

NASA Technical Reports Server (NTRS)

Jones, Clyde S., III; Venable, Richard A.

1998-01-01

The Marshall Space Flight Center has established a facility for the joining of large-scale aluminum-lithium alloy 2195 cryogenic fuel tanks using the friction-stir welding process. Longitudinal welds, approximately five meters in length, were made possible by retrofitting an existing vertical fusion weld system, designed to fabricate tank barrel sections ranging from two to ten meters in diameter. The structural design requirements of the tooling, clamping and the spindle travel system will be described in this paper. Process controls and real-time data acquisition will also be described, and were critical elements contributing to successful weld operation.

Impact of potential large-scale and medium-scale irrigation on the West African Monsoon and its dependence on location of irrigated area

NASA Astrophysics Data System (ADS)

Eltahir, E. A. B.; IM, E. S.

2014-12-01

This study investigates the impact of potential large-scale (about 400,000 km2) and medium-scale (about 60,000 km2) irrigation on the climate of West Africa using the MIT Regional Climate Model. A new irrigation module is implemented to assess the impact of location and scheduling of irrigation on rainfall distribution over West Africa. A control simulation (without irrigation) and various sensitivity experiments (with irrigation) are performed and compared to discern the effects of irrigation location, size and scheduling. In general, the irrigation-induced surface cooling due to anomalously wet soil tends to suppress moist convection and rainfall, which in turn induces local subsidence and low level anti-cyclonic circulation. These local effects are dominated by a consistent reduction of local rainfall over the irrigated land, irrespective of its location. However, the remote response of rainfall distribution to irrigation exhibits a significant sensitivity to the latitudinal position of irrigation. The low-level northeasterly flow associated with anti-cyclonic circulation centered over the irrigation area can enhance the extent of low level convergence through interaction with the prevailing monsoon flow, leading to significant increase in rainfall. Despite much reduced forcing of irrigation water, the medium-scale irrigation seems to draw the same response as large-scale irrigation, which supports the robustness of the response to irrigation in our modeling system. Both large-scale and medium-scale irrigation experiments show that an optimal irrigation location and scheduling exists that would lead to a more efficient use of irrigation water. The approach of using a regional climate model to investigate the impact of location and size of irrigation schemes may be the first step in incorporating land-atmosphere interactions in the design of location and size of irrigation projects. However, this theoretical approach is still in early stages of development and further research is needed before any practical application in water resources planning. Acknowledgements.This research was supported by the National Research Foundation Singapore through the Singapore MIT Alliance for Research and Technology's Center for Environmental Sensing and Modeling interdisciplinary research program.

A comprehensive study on urban true orthorectification

USGS Publications Warehouse

Zhou, G.; Chen, W.; Kelmelis, J.A.; Zhang, Dongxiao

2005-01-01

To provide some advanced technical bases (algorithms and procedures) and experience needed for national large-scale digital orthophoto generation and revision of the Standards for National Large-Scale City Digital Orthophoto in the National Digital Orthophoto Program (NDOP), this paper presents a comprehensive study on theories, algorithms, and methods of large-scale urban orthoimage generation. The procedures of orthorectification for digital terrain model (DTM)-based and digital building model (DBM)-based orthoimage generation and their mergence for true orthoimage generation are discussed in detail. A method of compensating for building occlusions using photogrammetric geometry is developed. The data structure needed to model urban buildings for accurately generating urban orthoimages is presented. Shadow detection and removal, the optimization of seamline for automatic mosaic, and the radiometric balance of neighbor images are discussed. Street visibility analysis, including the relationship between flight height, building height, street width, and relative location of the street to the imaging center, is analyzed for complete true orthoimage generation. The experimental results demonstrated that our method can effectively and correctly orthorectify the displacements caused by terrain and buildings in urban large-scale aerial images. ?? 2005 IEEE.

Multiresolution comparison of precipitation datasets for large-scale models

NASA Astrophysics Data System (ADS)

Chun, K. P.; Sapriza Azuri, G.; Davison, B.; DeBeer, C. M.; Wheater, H. S.

2014-12-01

Gridded precipitation datasets are crucial for driving large-scale models which are related to weather forecast and climate research. However, the quality of precipitation products is usually validated individually. Comparisons between gridded precipitation products along with ground observations provide another avenue for investigating how the precipitation uncertainty would affect the performance of large-scale models. In this study, using data from a set of precipitation gauges over British Columbia and Alberta, we evaluate several widely used North America gridded products including the Canadian Gridded Precipitation Anomalies (CANGRD), the National Center for Environmental Prediction (NCEP) reanalysis, the Water and Global Change (WATCH) project, the thin plate spline smoothing algorithms (ANUSPLIN) and Canadian Precipitation Analysis (CaPA). Based on verification criteria for various temporal and spatial scales, results provide an assessment of possible applications for various precipitation datasets. For long-term climate variation studies (~100 years), CANGRD, NCEP, WATCH and ANUSPLIN have different comparative advantages in terms of their resolution and accuracy. For synoptic and mesoscale precipitation patterns, CaPA provides appealing performance of spatial coherence. In addition to the products comparison, various downscaling methods are also surveyed to explore new verification and bias-reduction methods for improving gridded precipitation outputs for large-scale models.

White paper: A plan for cooperation between NASA and DARPA to establish a center for advanced architectures

NASA Technical Reports Server (NTRS)

Denning, P. J.; Adams, G. B., III; Brown, R. L.; Kanerva, P.; Leiner, B. M.; Raugh, M. R.

1986-01-01

Large, complex computer systems require many years of development. It is recognized that large scale systems are unlikely to be delivered in useful condition unless users are intimately involved throughout the design process. A mechanism is described that will involve users in the design of advanced computing systems and will accelerate the insertion of new systems into scientific research. This mechanism is embodied in a facility called the Center for Advanced Architectures (CAA). CAA would be a division of RIACS (Research Institute for Advanced Computer Science) and would receive its technical direction from a Scientific Advisory Board established by RIACS. The CAA described here is a possible implementation of a center envisaged in a proposed cooperation between NASA and DARPA.

US National Large-scale City Orthoimage Standard Initiative

USGS Publications Warehouse

Zhou, G.; Song, C.; Benjamin, S.; Schickler, W.

2003-01-01

The early procedures and algorithms for National digital orthophoto generation in National Digital Orthophoto Program (NDOP) were based on earlier USGS mapping operations, such as field control, aerotriangulation (derived in the early 1920's), the quarter-quadrangle-centered (3.75 minutes of longitude and latitude in geographic extent), 1:40,000 aerial photographs, and 2.5 D digital elevation models. However, large-scale city orthophotos using early procedures have disclosed many shortcomings, e.g., ghost image, occlusion, shadow. Thus, to provide the technical base (algorithms, procedure) and experience needed for city large-scale digital orthophoto creation is essential for the near future national large-scale digital orthophoto deployment and the revision of the Standards for National Large-scale City Digital Orthophoto in National Digital Orthophoto Program (NDOP). This paper will report our initial research results as follows: (1) High-precision 3D city DSM generation through LIDAR data processing, (2) Spatial objects/features extraction through surface material information and high-accuracy 3D DSM data, (3) 3D city model development, (4) Algorithm development for generation of DTM-based orthophoto, and DBM-based orthophoto, (5) True orthophoto generation by merging DBM-based orthophoto and DTM-based orthophoto, and (6) Automatic mosaic by optimizing and combining imagery from many perspectives.

The Direct Referral to Endovascular Center criteria: a proposal for pre-hospital evaluation of acute stroke in the Madrid Stroke Network.

PubMed

Rodríguez-Pardo, J; Fuentes, B; Alonso de Leciñana, M; Ximénez-Carrillo, Á; Zapata-Wainberg, G; Álvarez-Fraga, J; Barriga, F J; Castillo, L; Carneado-Ruiz, J; Díaz-Guzman, J; Egido-Herrero, J; de Felipe, A; Fernández-Ferro, J; Frade-Pardo, L; García-Gallardo, Á; García-Pastor, A; Gil-Núñez, A; Gómez-Escalonilla, C; Guillán, M; Herrero-Infante, Y; Masjuan-Vallejo, J; Ortega-Casarrubios, M Á; Vivancos-Mora, J; Díez-Tejedor, E

2017-03-01

For patients with acute ischaemic stroke due to large-vessel occlusion, it has recently been shown that mechanical thrombectomy (MT) with stent retrievers is better than medical treatment alone. However, few hospitals can provide MT 24 h/day 365 days/year, and it remains unclear whether selected patients with acute stroke should be directly transferred to the nearest MT-providing hospital to prevent treatment delays. Clinical scales such as Rapid Arterial Occlusion Evaluation (RACE) have been developed to predict large-vessel occlusion at a pre-hospital level, but their predictive value for MT is low. We propose new criteria to identify patients eligible for MT, with higher accuracy. The Direct Referral to Endovascular Center criteria were defined based on a retrospective cohort of 317 patients admitted to a stroke center. The association of age, sex, RACE scale score and blood pressure with the likelihood of receiving MT were analyzed. Cut-off points with the highest association were thereafter evaluated in a prospective cohort of 153 patients from nine stroke units comprising the Madrid Stroke Network. Patients with a RACE scale score ≥ 5, systolic blood pressure <190 mmHg and age <81 years showed a significantly higher probability of undergoing MT (odds ratio, 33.38; 95% confidence interval, 12-92.9). This outcome was confirmed in the prospective cohort, with 68% sensitivity, 84% specificity, 42% positive and 94% negative predictive values for MT, ruling out 83% of hemorrhagic strokes. The Direct Referral to Endovascular Center criteria could be useful for identifying patients suitable for MT. © 2017 EAN.

Data management for community research projects: A JGOFS case study

NASA Technical Reports Server (NTRS)

Lowry, Roy K.

1992-01-01

Since the mid 1980s, much of the marine science research effort in the United Kingdom has been focused into large scale collaborative projects involving public sector laboratories and university departments, termed Community Research Projects. Two of these, the Biogeochemical Ocean Flux Study (BOFS) and the North Sea Project incorporated large scale data collection to underpin multidisciplinary modeling efforts. The challenge of providing project data sets to support the science was met by a small team within the British Oceanographic Data Centre (BODC) operating as a topical data center. The role of the data center was to both work up the data from the ship's sensors and to combine these data with sample measurements into online databases. The working up of the data was achieved by a unique symbiosis between data center staff and project scientists. The project management, programming and data processing skills of the data center were combined with the oceanographic experience of the project communities to develop a system which has produced quality controlled, calibrated data sets from 49 research cruises in 3.5 years of operation. The data center resources required to achieve this were modest and far outweighed by the time liberated in the scientific community by the removal of the data processing burden. Two online project databases have been assembled containing a very high proportion of the data collected. As these are under the control of BODC their long term availability as part of the UK national data archive is assured. The success of the topical data center model for UK Community Research Project data management has been founded upon the strong working relationships forged between the data center and project scientists. These can only be established by frequent personal contact and hence the relatively small size of the UK has been a critical factor. However, projects covering a larger, even international scale could be successfully supported by a network of topical data centers managing online databases which are interconnected by object oriented distributed data management systems over wide area networks.

High-Resolution Subtropical Summer Precipitation Derived from Dynamical Downscaling of the NCEP-DOE Reanalysis: How Much Small-Scale Information Is Added by a Regional Model?

NASA Technical Reports Server (NTRS)

Lim, Young-Kwon; Stefanova, Lydia B.; Chan, Steven C.; Schubert, Siegfried D.; OBrien, James J.

2010-01-01

This study assesses the regional-scale summer precipitation produced by the dynamical downscaling of analyzed large-scale fields. The main goal of this study is to investigate how much the regional model adds smaller scale precipitation information that the large-scale fields do not resolve. The modeling region for this study covers the southeastern United States (Florida, Georgia, Alabama, South Carolina, and North Carolina) where the summer climate is subtropical in nature, with a heavy influence of regional-scale convection. The coarse resolution (2.5deg latitude/longitude) large-scale atmospheric variables from the National Center for Environmental Prediction (NCEP)/DOE reanalysis (R2) are downscaled using the NCEP Environmental Climate Prediction Center regional spectral model (RSM) to produce precipitation at 20 km resolution for 16 summer seasons (19902005). The RSM produces realistic details in the regional summer precipitation at 20 km resolution. Compared to R2, the RSM-produced monthly precipitation shows better agreement with observations. There is a reduced wet bias and a more realistic spatial pattern of the precipitation climatology compared with the interpolated R2 values. The root mean square errors of the monthly R2 precipitation are reduced over 93 (1,697) of all the grid points in the five states (1,821). The temporal correlation also improves over 92 (1,675) of all grid points such that the domain-averaged correlation increases from 0.38 (R2) to 0.55 (RSM). The RSM accurately reproduces the first two observed eigenmodes, compared with the R2 product for which the second mode is not properly reproduced. The spatial patterns for wet versus dry summer years are also successfully simulated in RSM. For shorter time scales, the RSM resolves heavy rainfall events and their frequency better than R2. Correlation and categorical classification (above/near/below average) for the monthly frequency of heavy precipitation days is also significantly improved by the RSM.

Analogue scale modelling of extensional tectonic processes using a large state-of-the-art centrifuge

NASA Astrophysics Data System (ADS)

Park, Heon-Joon; Lee, Changyeol

2017-04-01

Analogue scale modelling of extensional tectonic processes such as rifting and basin opening has been numerously conducted. Among the controlling factors, gravitational acceleration (g) on the scale models was regarded as a constant (Earth's gravity) in the most of the analogue model studies, and only a few model studies considered larger gravitational acceleration by using a centrifuge (an apparatus generating large centrifugal force by rotating the model at a high speed). Although analogue models using a centrifuge allow large scale-down and accelerated deformation that is derived by density differences such as salt diapir, the possible model size is mostly limited up to 10 cm. A state-of-the-art centrifuge installed at the KOCED Geotechnical Centrifuge Testing Center, Korea Advanced Institute of Science and Technology (KAIST) allows a large surface area of the scale-models up to 70 by 70 cm under the maximum capacity of 240 g-tons. Using the centrifuge, we will conduct analogue scale modelling of the extensional tectonic processes such as opening of the back-arc basin. Acknowledgement This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant number 2014R1A6A3A04056405).

Charting the Emergence of Corporate Procurement of Utility-Scale PV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heeter, Jenny S.; Cook, Jeffrey J.; Bird, Lori A.

Corporations and other institutions have contracted for more than 2300 MW of off-site solar, using power purchase agreements, green tariffs, or bilateral deals with utilities. This paper examines the benefits, challenges, and outlooks for large-scale off-site solar purchasing in the United States. Pathways differ based on where they are available, the hedge value they can provide, and their ease of implementation. The paper features case studies of an aggregate PPA (Massachusetts Institute of Technology, Boston Medical Center, and Post Office Square), a corporation exiting their incumbent utility (MGM Resorts), a utility offering large scale renewables to corporate customers (Alabama Powersmore » Renewable Procurement Program), and a company with approval to sell energy into wholesale markets (Google Energy Inc.).« less

Exposure to the World Trade Center Attack and the Use of Cigarettes and Alcohol Among New York City Public High-School Students

PubMed Central

Wu, Ping; Duarte, Cristiane S.; Mandell, Donald J.; Fan, Bin; Liu, Xinhua; Fuller, Cordelia J.; Musa, George; Cohen, Michael; Cohen, Patricia; Hoven, Christina W.

2006-01-01

We examined exposure to the World Trade Center attack and changes in cigarette smoking and drinking among 2731 New York City public high-school students evaluated 6 months after the attack. Increased drinking was associated with direct exposure to the World Trade Center attack (P < .05). Increased smoking was not directly associated with exposure to the World Trade Center attack but was marginally significantly associated with posttraumatic stress disorder (P= .06). Our findings suggest that targeted substance-use interventions for youths may be warranted after large-scale disasters. PMID:16571705

Externally blown flap noise research

NASA Technical Reports Server (NTRS)

Dorsch, R. G.

1974-01-01

The Lewis Research Center cold-flow model externally blown flap (EBF) noise research test program is summarized. Both engine under-the-wing and over-the-wing EBF wing section configurations were studied. Ten large scale and nineteen small scale EBF models were tested. A limited number of forward airspeed effect and flap noise suppression tests were also run. The key results and conclusions drawn from the flap noise tests are summarized and discussed.

Oklahoma Downbursts and Their Asymmetry.

DTIC Science & Technology

1986-11-01

velocity across the divergence center of at least 10 m s-1. Further, downbursts are called micro- bursts when they are 0.4-4 km in diameter, and macrobursts ...outflows in- vestigated in this study are larger-scale downbursts ( macrobursts ) that were imbedded in large intense convective storms. This does not...observed in this study were associated with intense convective storms and were generally of much larger horizontal scale ( macrobursts ). However, due to

A study of rotor and platform design trade-offs for large-scale floating vertical axis wind turbines

NASA Astrophysics Data System (ADS)

Griffith, D. Todd; Paquette, Joshua; Barone, Matthew; Goupee, Andrew J.; Fowler, Matthew J.; Bull, Diana; Owens, Brian

2016-09-01

Vertical axis wind turbines are receiving significant attention for offshore siting. In general, offshore wind offers proximity to large populations centers, a vast & more consistent wind resource, and a scale-up opportunity, to name a few beneficial characteristics. On the other hand, offshore wind suffers from high levelized cost of energy (LCOE) and in particular high balance of system (BoS) costs owing to accessibility challenges and limited project experience. To address these challenges associated with offshore wind, Sandia National Laboratories is researching large-scale (MW class) offshore floating vertical axis wind turbines (VAWTs). The motivation for this work is that floating VAWTs are a potential transformative technology solution to reduce offshore wind LCOE in deep-water locations. This paper explores performance and cost trade-offs within the design space for floating VAWTs between the configurations for the rotor and platform.

Intermountain Cyclogenesis: a Climatology and Multiscale Case Studies

NASA Astrophysics Data System (ADS)

Lee, Tiros Peijiun

1995-11-01

A detailed study of Intermountain cyclones over the western United States is conducted through climatological and case studies. An eleven-year (1976-1986) statistical survey shows that the Nevada cyclogenesis is mainly a springtime (March, April) event while a secondary maximum of cyclogenesis frequency is found in November. Nearly 75% of the Nevada cyclogenesis events (177 out of 237 cases) take place under large-scale westerly to southerly flow aloft across the Sierra Nevada Mountains, while 24% of the events (57 out of 237 cases) occur under northwesterly flow aloft. A composite study of these two types of the flow is shown to demonstrate how differences in large-scale topography affect Intermountain cyclogenesis processes. The result from a case study of 9-11 February 1984 reveals that an antecedent Nevada lee trough formed as a result of large-scale southwesterly flow aloft interacting with the underlying terrain well before the surface and upper-level troughs moved onshore. Subsequent cyclogenesis took place in situ with the axis of the trough as the center of large-scale quasi-geostrophic ascent/positive potential vorticity advection began to spread across the Sierra Nevada Mountains. As the cyclone moved downstream, it was observed to weaken well before reaching the Continental Divide while a new cyclonic development occurred east of the Rocky Mountains. It is shown that the weakening of the Intermountain cyclone was associated with the ongoing interaction between the Intermountain cyclone and large-scale topography and the progressive outrunning of the large-scale dynamical forcing aloft away from the surface cyclone center. An investigation of the large-scale evolution for the 26-29 January 1980 case, which developed beneath the northwesterly flow aloft, further reveals that the underlying topography plays two major roles in contributing to the initial cyclogenesis: (1) to block and to retard cold, stable air east of the Continental Divide from rushing into the Great Basin region, and (2) to produce differential pressure falls across the Sierra Nevada Mountains (more along the eastern slopes) in response to increasing cross -mountain flow. Numerous transient shortwaves in the midtroposphere rapidly move across the GB and the Rocky Mountains into the Plains States, while the Intermountain cyclone moves slower than to the disturbances aloft. There is no downstream lee trough/cyclogenesis to the east of the Rockies during the investigation period since the leeside is characterized by cold, stable air. The third case study is made of an 11-14 December 1987 Intermountain cyclogenesis case which took place in an area of relatively warm and less stable environment near the Arizona-New Mexico border beneath northwesterly flow aloft. The ensuing interaction between the large -scale flow and underlying terrain allowed the surface cyclone to remain quasi-stationary for its entire 36 h life span. We also document a cold-season small-scale Catalina eddy development in the coastal southern California waters in this case. The eddy formed as the equatorward and northeasterly flow upstream of the coastal (San Rafael and Saint Ynez) mountains increased in the lower troposphere. Weak large-scale ascent in the mid- and upper-troposphere over the incipient eddy environment provided evidence of the orographic nature of the small -scale cyclone. The eddy was eventually displaced seaward and weakened with the arrival of powerful large-scale subsidence and increasing northeasterly downslope flow at the lower levels that reached the coastal waters.

Linking Teleconnections and Iowa's Climate

NASA Astrophysics Data System (ADS)

Rowe, S. T.; Villarini, G.; Lavers, D. A.; Scoccimarro, E.

2013-12-01

In recent years Iowa and the U.S. Midwest has experienced both extreme drought and flood periods. With a drought in 2012 bounded by major floods in 2011 and 2013, the rapid progression from one extreme to the next is on the forefront of the public mind. Given that Iowa is a major agricultural state, extreme weather conditions can have severe socioeconomic consequences. In this research we investigate the large-scale climate processes that occurred concurrently and before a range of dry/wet and cold/hot periods to improve process understanding of these events. It is essential to understand the large-scale climate processes, as these can then provide valuable insight toward the development of long-term climate forecasts for Iowa. In this study monthly and seasonal surface temperature and precipitation over 1950-2012 across Iowa are used. Precipitation and surface temperature data are retrieved from the Parameter-elevation Regressions on Independent Slopes Model (PRISM) Climate Group at Oregon State University. The large-scale atmospheric fields are obtained from the National Center for Environmental Prediction (NCEP) / National Center for Atmospheric Research (NCAR) Reanalysis 1 Project. Precipitation is stratified according to wet, normal, and dry conditions, while temperature according to hot, average, and cold periods. Different stratification criteria based on the precipitation and temperature distributions are examined. Mean sea-level pressure and sea-surface temperature composite maps for the northern hemisphere are then produced for the wet/dry conditions, and cold/hot conditions. Further analyses include correlation, anomalies, and assessment of large-scale planetary wave activity, shedding light on the differences and similarities among the opposite weather conditions. The results of this work will highlight regional weather patterns that are related to the climate over Iowa, providing valuable insight into the mechanisms controlling the occurrence of potentially extreme weather conditions over this area.

Pioneering University/Industry Venture Explores VLSI Frontiers.

ERIC Educational Resources Information Center

Davis, Dwight B.

1983-01-01

Discusses industry-sponsored programs in semiconductor research, focusing on Stanford University's Center for Integrated Systems (CIS). CIS, while pursuing research in semiconductor very-large-scale integration, is merging the fields of computer science, information science, and physical science. Issues related to these university/industry…

Measurements of the center-of-mass energies at BESIII via the di-muon process

NASA Astrophysics Data System (ADS)

Ablikim, M.; N. Achasov, M.; C. Ai, X.; Albayrak, O.; Albrecht, M.; J. Ambrose, D.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Baldini, Ferroli R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Y. Deng, Z.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Fava, L.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, X. Y.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Q. Hao, X. Q.; Harris, F. A.; He, K. L.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. M.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang Y.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kühn, W.; Kupsc, A.; Lange, J. S.; Lara, M.; Larin, P.; Leng, C.; Li, C.; Cheng, Li; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. M.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, X.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Fang, Liu; Feng, Liu; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, H. J; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Maas, F. E.; Maggiora, M.; Mao, Y. Y.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Min, J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Moriya, K.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Santoro, V.; Sarantsev, A. A.; Savrié, M.; Schoenning, B. K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, S. G.; Wang, W.; Wang, W. P.; Wang, X. F.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Wei, J. B.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, A. Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. N.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; , S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

2016-06-01

From 2011 to 2014, the BESIII experiment collected about 5 fb-1 data at center-of-mass energies around 4 GeV for the studies of the charmonium-like and higher excited charmonium states. By analyzing the di-muon process e+e- → γISR/FSRμ+μ-, the center-of-mass energies of the data samples are measured with a precision of 0.8 MeV. The center-of-mass energy is found to be stable for most of the time during data taking. Supported by National Key Basic Research Program of China (2015CB856700), National Natural Science Foundation of China (11125525, 11235011, 11322544, 11335008, 11425524, Y61137005C), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, CAS Center for Excellence in Particle Physics (CCEPP), Collaborative Innovation Center for Particles and Interactions (CICPI), Joint Large-Scale Scientific Facility Funds of NSFC and CAS (11179007, U1232201, U1332201), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, National 1000 Talents Program of China, INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy, Ministry of Development of Turkey (DPT2006K-120470), Russian Foundation for Basic Research (14-07-91152), Swedish Research Council, U. S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0).

Large-Scale Hybrid Motor Testing. Chapter 10

NASA Technical Reports Server (NTRS)

Story, George

2006-01-01

Hybrid rocket motors can be successfully demonstrated at a small scale virtually anywhere. There have been many suitcase sized portable test stands assembled for demonstration of hybrids. They show the safety of hybrid rockets to the audiences. These small show motors and small laboratory scale motors can give comparative burn rate data for development of different fuel/oxidizer combinations, however questions that are always asked when hybrids are mentioned for large scale applications are - how do they scale and has it been shown in a large motor? To answer those questions, large scale motor testing is required to verify the hybrid motor at its true size. The necessity to conduct large-scale hybrid rocket motor tests to validate the burn rate from the small motors to application size has been documented in several place^'^^.^. Comparison of small scale hybrid data to that of larger scale data indicates that the fuel burn rate goes down with increasing port size, even with the same oxidizer flux. This trend holds for conventional hybrid motors with forward oxidizer injection and HTPB based fuels. While the reason this is occurring would make a great paper or study or thesis, it is not thoroughly understood at this time. Potential causes include the fact that since hybrid combustion is boundary layer driven, the larger port sizes reduce the interaction (radiation, mixing and heat transfer) from the core region of the port. This chapter focuses on some of the large, prototype sized testing of hybrid motors. The largest motors tested have been AMROC s 250K-lbf thrust motor at Edwards Air Force Base and the Hybrid Propulsion Demonstration Program s 250K-lbf thrust motor at Stennis Space Center. Numerous smaller tests were performed to support the burn rate, stability and scaling concepts that went into the development of those large motors.

The impact of a large-scale power outage on hemodialysis center operations.

PubMed

Abir, Mahshid; Jan, Sophia; Jubelt, Lindsay; Merchant, Raina M; Lurie, Nicole

2013-12-01

On June 29, 2012, mid-Atlantic storms resulted in a large-scale power outage affecting up to three million people across multiple (US) states. Hemodialysis centers are dependent on electricity to provide dialysis care to end-stage renal disease patients. The objective of this study was to determine how the power outage impacted operations in a sample of hemodialysis centers in the impacted regions. The sample consisted of all hemodialysis centers located in the District of Columbia and a total of five counties with the largest power losses in West Virginia, Virginia, and Maryland. A semi-structured interview guide was developed, and the charge nurse or supervisor in each facility was interviewed. The survey questions addressed whether their centers lost power, if so, for how long, where their patients received dialysis, whether their centers had backup generators, and if so, whether they had any problems operating them, and whether their center received patients from other centers if they had power. Calls were placed to 90 dialysis centers in the sampled areas and a 90% response rate was achieved. Overall, hemodialysis operations at approximately 30% (n = 24) of the centers queried were impacted by the power outage. Of the 36 centers that lost power, 31% (n = 11) referred their patients to other dialysis centers, 22% (n = 8) accommodated their patients during a later shift or on a different day; the rest of the centers either experienced brief power outages that did not affect operations or experienced a power outage on days that the center is usually closed. Some centers in the study cohort reported receiving patients from other centers for dialysis 33% (n = 27). Thirty-two percent (n = 26) of the centers queried had backup generators on site. Eleven percent (n = 4) of the centers experiencing power outages reported that backup generators were brought in by their parent companies. Comprehensive emergency planning for dialysis centers should include provisions for having backup generators on site, having plans in place for the timely delivery of a generator during a power outage, or having predesignated backup dialysis centers for patients to receive dialysis during emergencies. Most dialysis centers surveyed in this study were able to sustain continuity of care by implementing such pre-existing emergency plans.

A Mixed-dimensional Model for Determining the Impact of Permafrost Polygonal Ground Degradation on Arctic Hydrology.

NASA Astrophysics Data System (ADS)

Coon, E.; Jan, A.; Painter, S. L.; Moulton, J. D.; Wilson, C. J.

2017-12-01

Many permafrost-affected regions in the Arctic manifest a polygonal patterned ground, which contains large carbon stores and is vulnerability to climate change as warming temperatures drive melting ice wedges, polygon degradation, and thawing of the underlying carbon-rich soils. Understanding the fate of this carbon is difficult. The system is controlled by complex, nonlinear physics coupling biogeochemistry, thermal-hydrology, and geomorphology, and there is a strong spatial scale separation between microtopograpy (at the scale of an individual polygon) and the scale of landscape change (at the scale of many thousands of polygons). Physics-based models have come a long way, and are now capable of representing the diverse set of processes, but only on individual polygons or a few polygons. Empirical models have been used to upscale across land types, including ecotypes evolving from low-centered (pristine) polygons to high-centered (degraded) polygon, and do so over large spatial extent, but are limited in their ability to discern causal process mechanisms. Here we present a novel strategy that looks to use physics-based models across scales, bringing together multiple capabilities to capture polygon degradation under a warming climate and its impacts on thermal-hydrology. We use fine-scale simulations on individual polygons to motivate a mixed-dimensional strategy that couples one-dimensional columns representing each individual polygon through two-dimensional surface flow. A subgrid model is used to incorporate the effects of surface microtopography on surface flow; this model is described and calibrated to fine-scale simulations. And critically, a subsidence model that tracks volume loss in bulk ice wedges is used to alter the subsurface structure and subgrid parameters, enabling the inclusion of the feedbacks associated with polygon degradation. This combined strategy results in a model that is able to capture the key features of polygon permafrost degradation, but in a simulation across a large spatial extent of polygonal tundra.

Signatures of the Primordial Universe from Its Emptiness: Measurement of Baryon Acoustic Oscillations from Minima of the Density Field.

PubMed

Kitaura, Francisco-Shu; Chuang, Chia-Hsun; Liang, Yu; Zhao, Cheng; Tao, Charling; Rodríguez-Torres, Sergio; Eisenstein, Daniel J; Gil-Marín, Héctor; Kneib, Jean-Paul; McBride, Cameron; Percival, Will J; Ross, Ashley J; Sánchez, Ariel G; Tinker, Jeremy; Tojeiro, Rita; Vargas-Magana, Mariana; Zhao, Gong-Bo

2016-04-29

Sound waves from the primordial fluctuations of the Universe imprinted in the large-scale structure, called baryon acoustic oscillations (BAOs), can be used as standard rulers to measure the scale of the Universe. These oscillations have already been detected in the distribution of galaxies. Here we propose to measure BAOs from the troughs (minima) of the density field. Based on two sets of accurate mock halo catalogues with and without BAOs in the seed initial conditions, we demonstrate that the BAO signal cannot be obtained from the clustering of classical disjoint voids, but it is clearly detected from overlapping voids. The latter represent an estimate of all troughs of the density field. We compute them from the empty circumsphere centers constrained by tetrahedra of galaxies using Delaunay triangulation. Our theoretical models based on an unprecedented large set of detailed simulated void catalogues are remarkably well confirmed by observational data. We use the largest recently publicly available sample of luminous red galaxies from SDSS-III BOSS DR11 to unveil for the first time a >3σ BAO detection from voids in observations. Since voids are nearly isotropically expanding regions, their centers represent the most quiet places in the Universe, keeping in mind the cosmos origin and providing a new promising window in the analysis of the cosmological large-scale structure from galaxy surveys.

PREPping Students for Authentic Science

ERIC Educational Resources Information Center

Dolan, Erin L.; Lally, David J.; Brooks, Eric; Tax, Frans E.

2008-01-01

In this article, the authors describe a large-scale research collaboration, the Partnership for Research and Education in Plants (PREP), which has capitalized on publicly available databases that contain massive amounts of biological information; stock centers that house and distribute inexpensive organisms with different genotypes; and the…

Factors Influencing College Science Success

ERIC Educational Resources Information Center

Tai, Robert H.; Sadler, Philip M.; Mintzes, Joel J.

2006-01-01

In this paper, the authors report some of the salient findings of a large-scale, four-year national study, conducted at the Harvard-Smithsonian Center for Astrophysics, entitled "Factors Influencing College Science Success" (FICSS), which surveyed college students who enrolled in first-year biology, chemistry, and physics courses…

Get It Together

ERIC Educational Resources Information Center

Coffey, Dave

2006-01-01

The scale of the mechanical and plumbing systems required to support a large, multi-building academic health sciences/research center entails a lot of ductwork. Getting mechanical systems installed and running while carrying out activities from other building disciplines requires a great deal of coordinated effort. A university and its…

The Practical Impact of Recent Computer Advances on the Analysis and Design of Large Scale Networks

DTIC Science & Technology

1974-06-01

Capacity Considerations," ARPA Network Information Center, Stanford Research Institute. 10. Gitman , I., R. M. VanSlyke, H. Frank: "On Splitting...281-285. 12. Gitman , I., "On : ^e Capacity of Slotted ALOHA Networks and Some Design Problems", ARPANET Network Information Center, Stanford...sum of the average demands of that population." Gitman , Van Slyke, and Frank [3], have addressed the problem of splitting a channel between two

Sources of Wind Variability at a Single Station in Complex Terrain During Tropical Cyclone Passage

DTIC Science & Technology

2013-12-01

Mesoscale Prediction System CPA Closest point of approach ET Extratropical transition FNMOC Fleet Numerical Meteorology and Oceanography Center...forecasts. However, 2 the TC forecast tracks and warnings they issue necessarily focus on the large-scale structure of the storm , and are not...winds at one station. Also, this technique is a storm - centered forecast and even if the grid spacing is on order of one kilometer, it is unlikely

Ammunition Suite for the FCS Multi-role Armament and Ammunition System (MRAAS)

DTIC Science & Technology

2001-06-20

Cards Large Scale Gap Test (LSGT) Exploding Foil Initiator ( EFI ) Effort 19 Slow Burning Layer Fast Burning Layer FASTCORE Nitramines ETPEs RDX CL20...Center Burst Charge 48 M80 Grenades With Center Burst Charge ü Trade off performance with size, weight, etc. ü Develop initial space claim for...submunition ü Dynamic Analysis of projectile for different submunitions MRAAS Trades underway • Accomplishments – Initial meetings with TRADOC, Ft Knox and Ft

Iterative quantization: a Procrustean approach to learning binary codes for large-scale image retrieval.

PubMed

Gong, Yunchao; Lazebnik, Svetlana; Gordo, Albert; Perronnin, Florent

2013-12-01

This paper addresses the problem of learning similarity-preserving binary codes for efficient similarity search in large-scale image collections. We formulate this problem in terms of finding a rotation of zero-centered data so as to minimize the quantization error of mapping this data to the vertices of a zero-centered binary hypercube, and propose a simple and efficient alternating minimization algorithm to accomplish this task. This algorithm, dubbed iterative quantization (ITQ), has connections to multiclass spectral clustering and to the orthogonal Procrustes problem, and it can be used both with unsupervised data embeddings such as PCA and supervised embeddings such as canonical correlation analysis (CCA). The resulting binary codes significantly outperform several other state-of-the-art methods. We also show that further performance improvements can result from transforming the data with a nonlinear kernel mapping prior to PCA or CCA. Finally, we demonstrate an application of ITQ to learning binary attributes or "classemes" on the ImageNet data set.

Evaluation of the Atlantic Multidecadal Oscillation Impact on Large-Scale Atmospheric Circulation in the Atlantic Region in Summer

NASA Astrophysics Data System (ADS)

Semenov, V. A.; Cherenkova, E. A.

2018-02-01

The influence of the Atlantic Multidecadal Oscillation (AMO) on large-scale atmospheric circulation in the Atlantic region in summer for the period of 1950-2015 is investigated. It is shown that the intensification of the summer North Atlantic Oscillation (NAO) with significant changes in sea level pressure anomalies in the main centers of action (over Greenland and the British Isles) occurred while the North Atlantic was cooler. Sea surface temperature anomalies, which are linked to the AMO in the summer season, affect both the NAO index and fluctuations of the Eastern Atlantic/Western Russia (EAWR) centers of action. The positive (negative) phase of the AMO is characterized by a combination of negative (positive) values of the NAO and EAWR indices. The dominance of the opposite phases of the teleconnection indices in summer during the warm North Atlantic and in its colder period resulted in differences in the regional climate in Europe.

First-principles study of the binding energy between nanostructures and its scaling with system size

NASA Astrophysics Data System (ADS)

Tao, Jianmin; Jiao, Yang; Mo, Yuxiang; Yang, Zeng-Hui; Zhu, Jian-Xin; Hyldgaard, Per; Perdew, John P.

2018-04-01

The equilibrium van der Waals binding energy is an important factor in the design of materials and devices. However, it presents great computational challenges for materials built up from nanostructures. Here we investigate the binding-energy scaling behavior from first-principles calculations. We show that the equilibrium binding energy per atom between identical nanostructures can scale up or down with nanostructure size, but can be parametrized for large N with an analytical formula (in meV/atom), Eb/N =a +b /N +c /N2+d /N3 , where N is the number of atoms in a nanostructure and a , b , c , and d are fitting parameters, depending on the properties of a nanostructure. The formula is consistent with a finite large-size limit of binding energy per atom. We find that there are two competing factors in the determination of the binding energy: Nonadditivities of van der Waals coefficients and center-to-center distance between nanostructures. To decode the detail, the nonadditivity of the static multipole polarizability is investigated from an accurate spherical-shell model. We find that the higher-order multipole polarizability displays ultrastrong intrinsic nonadditivity, no matter if the dipole polarizability is additive or not.

Managing large-scale workflow execution from resource provisioning to provenance tracking: The CyberShake example

USGS Publications Warehouse

Deelman, E.; Callaghan, S.; Field, E.; Francoeur, H.; Graves, R.; Gupta, N.; Gupta, V.; Jordan, T.H.; Kesselman, C.; Maechling, P.; Mehringer, J.; Mehta, G.; Okaya, D.; Vahi, K.; Zhao, L.

2006-01-01

This paper discusses the process of building an environment where large-scale, complex, scientific analysis can be scheduled onto a heterogeneous collection of computational and storage resources. The example application is the Southern California Earthquake Center (SCEC) CyberShake project, an analysis designed to compute probabilistic seismic hazard curves for sites in the Los Angeles area. We explain which software tools were used to build to the system, describe their functionality and interactions. We show the results of running the CyberShake analysis that included over 250,000 jobs using resources available through SCEC and the TeraGrid. ?? 2006 IEEE.

Technology and testing.

PubMed

Quellmalz, Edys S; Pellegrino, James W

2009-01-02

Large-scale testing of educational outcomes benefits already from technological applications that address logistics such as development, administration, and scoring of tests, as well as reporting of results. Innovative applications of technology also provide rich, authentic tasks that challenge the sorts of integrated knowledge, critical thinking, and problem solving seldom well addressed in paper-based tests. Such tasks can be used on both large-scale and classroom-based assessments. Balanced assessment systems can be developed that integrate curriculum-embedded, benchmark, and summative assessments across classroom, district, state, national, and international levels. We discuss here the potential of technology to launch a new era of integrated, learning-centered assessment systems.

The efficacy of student-centered instruction in supporting science learning.

PubMed

Granger, E M; Bevis, T H; Saka, Y; Southerland, S A; Sampson, V; Tate, R L

2012-10-05

Transforming science learning through student-centered instruction that engages students in a variety of scientific practices is central to national science-teaching reform efforts. Our study employed a large-scale, randomized-cluster experimental design to compare the effects of student-centered and teacher-centered approaches on elementary school students' understanding of space-science concepts. Data included measures of student characteristics and learning and teacher characteristics and fidelity to the instructional approach. Results reveal that learning outcomes were higher for students enrolled in classrooms engaging in scientific practices through a student-centered approach; two moderators were identified. A statistical search for potential causal mechanisms for the observed outcomes uncovered two potential mediators: students' understanding of models and evidence and the self-efficacy of teachers.

Experimental investigation of an ejector-powered free-jet facility

NASA Technical Reports Server (NTRS)

Long, Mary JO

1992-01-01

NASA Lewis Research Center's (LeRC) newly developed Nozzle Acoustic Test Rig (NATR) is a large free-jet test facility powered by an ejector system. In order to assess the pumping performance of this ejector concept and determine its sensitivity to various design parameters, a 1/5-scale model of the NATR was built and tested prior to the operation of the actual facility. This paper discusses the results of the 1/5-scale model tests and compares them with the findings from the full-scale tests.

Overview of Dynamic Test Techniques for Flight Dynamics Research at NASA LaRC (Invited)

NASA Technical Reports Server (NTRS)

Owens, D. Bruce; Brandon, Jay M.; Croom, Mark A.; Fremaux, C. Michael; Heim, Eugene H.; Vicroy, Dan D.

2006-01-01

An overview of dynamic test techniques used at NASA Langley Research Center on scale models to obtain a comprehensive flight dynamics characterization of aerospace vehicles is presented. Dynamic test techniques have been used at Langley Research Center since the 1920s. This paper will provide a partial overview of the current techniques available at Langley Research Center. The paper will discuss the dynamic scaling necessary to address the often hard-to-achieve similitude requirements for these techniques. Dynamic test techniques are categorized as captive, wind tunnel single degree-of-freedom and free-flying, and outside free-flying. The test facilities, technique specifications, data reduction, issues and future work are presented for each technique. The battery of tests conducted using the Blended Wing Body aircraft serves to illustrate how the techniques, when used together, are capable of characterizing the flight dynamics of a vehicle over a large range of critical flight conditions.

Evaluation and comparison of health care Work Environment Scale in military settings.

PubMed

Maloney, J P; Anderson, F D; Gladd, D L; Brown, D L; Hardy, M A

1996-05-01

The purpose of this study was to describe health care providers' perceptions of their work environment at a large U.S. Army medical center, and to compare the findings to other military medical centers. The sample (N = 112) consisted of the professional nursing staff working on the nine inpatient units. The Work Environmental Scale (WES) was used to measure perceptions of the workplace relative to gender, position (head nurses, staff nurses, and agency nurses), specialty nursing (intensive care unit [ICU] versus non-ICU), education (MSN, BSN, and ADN), and patterns of differences between the WES subscales of four military medical centers. Results of the study indicate that there were no significant gender differences. Head nurses, non-ICU nurses, and MSN nurses perceived their environment more positively. There were significant differences in the WES subscales between the military hospitals. Implications for nursing using the WES were recommended.

Cloud-enabled large-scale land surface model simulations with the NASA Land Information System

NASA Astrophysics Data System (ADS)

Duffy, D.; Vaughan, G.; Clark, M. P.; Peters-Lidard, C. D.; Nijssen, B.; Nearing, G. S.; Rheingrover, S.; Kumar, S.; Geiger, J. V.

2017-12-01

Developed by the Hydrological Sciences Laboratory at NASA Goddard Space Flight Center (GSFC), the Land Information System (LIS) is a high-performance software framework for terrestrial hydrology modeling and data assimilation. LIS provides the ability to integrate satellite and ground-based observational products and advanced modeling algorithms to extract land surface states and fluxes. Through a partnership with the National Center for Atmospheric Research (NCAR) and the University of Washington, the LIS model is currently being extended to include the Structure for Unifying Multiple Modeling Alternatives (SUMMA). With the addition of SUMMA in LIS, meaningful simulations containing a large multi-model ensemble will be enabled and can provide advanced probabilistic continental-domain modeling capabilities at spatial scales relevant for water managers. The resulting LIS/SUMMA application framework is difficult for non-experts to install due to the large amount of dependencies on specific versions of operating systems, libraries, and compilers. This has created a significant barrier to entry for domain scientists that are interested in using the software on their own systems or in the cloud. In addition, the requirement to support multiple run time environments across the LIS community has created a significant burden on the NASA team. To overcome these challenges, LIS/SUMMA has been deployed using Linux containers, which allows for an entire software package along with all dependences to be installed within a working runtime environment, and Kubernetes, which orchestrates the deployment of a cluster of containers. Within a cloud environment, users can now easily create a cluster of virtual machines and run large-scale LIS/SUMMA simulations. Installations that have taken weeks and months can now be performed in minutes of time. This presentation will discuss the steps required to create a cloud-enabled large-scale simulation, present examples of its use, and describe the potential deployment of this information technology with other NASA applications.

Comparative Effectiveness Research and Children With Cerebral Palsy: Identifying a Conceptual Framework and Specifying Measures.

PubMed

Gannotti, Mary E; Law, Mary; Bailes, Amy F; OʼNeil, Margaret E; Williams, Uzma; DiRezze, Briano

2016-01-01

A step toward advancing research about rehabilitation service associated with positive outcomes for children with cerebral palsy is consensus about a conceptual framework and measures. A Delphi process was used to establish consensus among clinicians and researchers in North America. Directors of large pediatric rehabilitation centers, clinicians from large hospitals, and researchers with expertise in outcomes participated (N = 18). Andersen's model of health care utilization framed outcomes: consumer satisfaction, activity, participation, quality of life, and pain. Measures agreed upon included Participation and Environment Measure for Children and Youth, Measure of Processes of Care, PEDI-CAT, KIDSCREEN-10, PROMIS Pediatric Pain Interference Scale, Visual Analog Scale for pain intensity, PROMIS Global Health Short Form, Family Environment Scale, Family Support Scale, and functional classification levels for gross motor, manual ability, and communication. Universal forms for documenting service use are needed. Findings inform clinicians and researchers concerned with outcome assessment.

“Real-Time” Cosmology with Extragalactic Proper Motions: the Secular Aberration Drift and Evolution of Large-Scale Structure

NASA Astrophysics Data System (ADS)

Truebenbach, Alexandra; Darling, Jeremy

2018-01-01

We present the VLBA Extragalactic Proper Motion Catalog, a catalog of extragalactic proper motions created using archival VLBI data and our own VLBA astrometry. The catalog contains 713 proper motions, with average uncertainties of ~ 24 microarcsec/yr, including 40 new or improved proper motion measurements using relative astrometry with the VLBA. We detect the secular aberration drift – the apparent motion of extragalactic objects caused by the solar system's acceleration around the Galactic Center – at 6.3 sigma significance with an amplitude of 1.69 +/- 0.27 microarcsec/yr and an apex consistent with the Galactic Center (275.2 +/- 10.0 deg, -29.4 +/- 8.8 deg). Our dipole model detects the aberration drift at a higher significance than some previous studies (e.g., Titov & Lambert 2013), but at a lower amplitude than expected or previously measured. We then use the correlated relative proper motions of extragalactic objects to place upper limits on the rate of large-scale structure collapse (e.g., Quercellini et al. 2009; Darling 2013). Pairs of small separation objects that are in gravitationally interacting structures such as filaments of large-scale structure will show a net decrease in angular separation (> - 15.5 microarcsec/yr) as they move towards each other, while pairs of large separation objects that are gravitationally unbound and move with the Hubble expansion will show no net change in angular separation. With our catalog, we place a 3 sigma limit on the rate of convergence of large-scale structure of -11.4 microarcsec/yr for extragalactic objects within 100 comoving Mpc of each other. We also confirm that large separation objects (> 800 comoving Mpc) move with the Hubble flow to within ~ 2.2 microarcsec/yr. In the future, we plan to incorporate the upcoming Gaia proper motions into our catalog to achieve a higher precision measurement of the average relative proper motion of gravitationally interacting extragalactic objects and to refine our measurement of the collapse of large-scale structure. This research was performed with support from the NSF grant AST-1411605.Darling, J. 2013, AJ, 777, L21; Quercellini et al. 2009. Phys. Rev. Lett., 102, 151302; Titov, O. & Lambert, S. 2013, A&A, 559, A95

Investigating a link between large and small-scale chaos features on Europa

NASA Astrophysics Data System (ADS)

Tognetti, L.; Rhoden, A.; Nelson, D. M.

2017-12-01

Chaos is one of the most recognizable, and studied, features on Europa's surface. Most models of chaos formation invoke liquid water at shallow depths within the ice shell; the liquid destabilizes the overlying ice layer, breaking it into mobile rafts and destroying pre-existing terrain. This class of model has been applied to both large-scale chaos like Conamara and small-scale features (i.e. microchaos), which are typically <10 km in diameter. Currently unknown, however, is whether both large-scale and small-scale features are produced together, e.g. through a network of smaller sills linked to a larger liquid water pocket. If microchaos features do form as satellites of large-scale chaos features, we would expect a drop off in the number density of microchaos with increasing distance from the large chaos feature; the trend should not be observed in regions without large-scale chaos features. Here, we test the hypothesis that large chaos features create "satellite" systems of smaller chaos features. Either outcome will help us better understand the relationship between large-scale chaos and microchaos. We focus first on regions surrounding the large chaos features Conamara and Murias (e.g. the Mitten). We map all chaos features within 90,000 sq km of the main chaos feature and assign each one a ranking (High Confidence, Probable, or Low Confidence) based on the observed characteristics of each feature. In particular, we look for a distinct boundary, loss of preexisting terrain, the existence of rafts or blocks, and the overall smoothness of the feature. We also note features that are chaos-like but lack sufficient characteristics to be classified as chaos. We then apply the same criteria to map microchaos features in regions of similar area ( 90,000 sq km) that lack large chaos features. By plotting the distribution of microchaos with distance from the center point of the large chaos feature or the mapping region (for the cases without a large feature), we determine whether there is a distinct signature linking large-scale chaos features with nearby microchaos. We discuss the implications of these results on the process of chaos formation and the extent of liquid water within Europa's ice shell.

Bayesian methods to determine performance differences and to quantify variability among centers in multi-center trials: the IHAST trial.

PubMed

Bayman, Emine O; Chaloner, Kathryn M; Hindman, Bradley J; Todd, Michael M

2013-01-16

To quantify the variability among centers and to identify centers whose performance are potentially outside of normal variability in the primary outcome and to propose a guideline that they are outliers. Novel statistical methodology using a Bayesian hierarchical model is used. Bayesian methods for estimation and outlier detection are applied assuming an additive random center effect on the log odds of response: centers are similar but different (exchangeable). The Intraoperative Hypothermia for Aneurysm Surgery Trial (IHAST) is used as an example. Analyses were adjusted for treatment, age, gender, aneurysm location, World Federation of Neurological Surgeons scale, Fisher score and baseline NIH stroke scale scores. Adjustments for differences in center characteristics were also examined. Graphical and numerical summaries of the between-center standard deviation (sd) and variability, as well as the identification of potential outliers are implemented. In the IHAST, the center-to-center variation in the log odds of favorable outcome at each center is consistent with a normal distribution with posterior sd of 0.538 (95% credible interval: 0.397 to 0.726) after adjusting for the effects of important covariates. Outcome differences among centers show no outlying centers. Four potential outlying centers were identified but did not meet the proposed guideline for declaring them as outlying. Center characteristics (number of subjects enrolled from the center, geographical location, learning over time, nitrous oxide, and temporary clipping use) did not predict outcome, but subject and disease characteristics did. Bayesian hierarchical methods allow for determination of whether outcomes from a specific center differ from others and whether specific clinical practices predict outcome, even when some centers/subgroups have relatively small sample sizes. In the IHAST no outlying centers were found. The estimated variability between centers was moderately large.

Integrated energy system for the Asphalt Green Youth Sports and Arts Center and the Fireboat House

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barron, J.; Cole, W.J.

Energy conservation and solar energy measures are described for two old buildings, different in scale and character, that are being recycled by the Neighborhood Committee for the Asphalt Green into a community Sports and Arts Center and an Environmental Studies Center. The approach taken by the Authority in developing the integrated energy system design for the larger, commercial-scale Sports and Arts Center was to incorporate energy conservation and renewable energy measures that minimize life cycle costs. The benefits of this approach are significant. As documented in this report, energy costs will be reduced from about $50,000 per year (in 1979more » dollars) to $15,000 per year. The final design incorporates exterior shell insulation, on-site mechanical equipment, and a wind energy conversion system to generate electricity for the large lighting and cooling requirements, heat recovery from the ventilation exhaust air, generator motors and refrigeration system, and hot and cold thermal storage for load management. The Environmental Studies Center, formerly a fireboat station on the East River, is a smaller residential-scale structure. The approach in developing the renovation plan was to assess retrofit potential for cost-effective energy conservation, solar domestic hot water, and active and passive solar space heating. Energy measures were selected which would maximize educational potential for school children and which could be replicated by the general public.« less

Optimizing C-17 Pacific Basing

DTIC Science & Technology

2014-05-01

Starlifter and C-5 Galaxy turbofan -powered aircraft (Owen, 2014). Pax Americana was characterized by a busy and steady operating environment for US global...center of the Pacific as well as the north and western Pacific rim (Owen, 2014). Turbofan airlifters began to be integrated into the large-scale

Test Design Considerations for Students with Significant Cognitive Disabilities

ERIC Educational Resources Information Center

Anderson, Daniel; Farley, Dan; Tindal, Gerald

2015-01-01

Students with significant cognitive disabilities present an assessment dilemma that centers on access and validity in large-scale testing programs. Typically, access is improved by eliminating construct-irrelevant barriers, while validity is improved, in part, through test standardization. In this article, one state's alternate assessment data…

Tony Jimenez | NREL

Science.gov Websites

pre-feasibility analysis; wind data analysis; the small wind turbine certification process; economic Regional Test Center effort, analysis of the potential economic impact of large-scale MHK deployment off pre-feasibility analysis. Tony is an engineer officer in the Army Reserve. He has deployed twice

Nancy Dowe | NREL

Science.gov Websites

Center Bioprocess Development Group. The group is largely made up of fermentation scientists and engineers whose focus is on fermentation process development and pilot plant scale-up. Dowe has nearly 30 years of experience working with a wide variety of fermentation processes and microorganisms for the

Expansive Northern Volcanic Plains

NASA Image and Video Library

2015-04-16

Mercury northern region is dominated by expansive smooth plains, created by huge amounts of volcanic material flooding across Mercury surface in the past, as seen by NASA MESSENGER spacecraft. The volcanic lava flows buried craters, leaving only traces of their rims visible. Such craters are called ghost craters, and there are many visible in this image, including a large one near the center. Wrinkle ridges cross this scene and small troughs are visible regionally within ghost craters, formed as a result of the lava cooling. The northern plains are often described as smooth since their surface has fewer impact craters and thus has been less battered by such events. This indicates that these volcanic plains are younger than Mercury's rougher surfaces. Instrument: Mercury Dual Imaging System (MDIS) Center Latitude: 60.31° N Center Longitude: 36.87° E Scale: The large ghost crater at the center of the image is approximately 103 kilometers (64 miles) in diameter http://photojournal.jpl.nasa.gov/catalog/PIA19415

An investigation of small scales of turbulence in a boundary layer at high Reynolds numbers

NASA Technical Reports Server (NTRS)

Wallace, James M.; Ong, L.; Balint, J.-L.

1993-01-01

The assumption that turbulence at large wave-numbers is isotropic and has universal spectral characteristics which are independent of the flow geometry, at least for high Reynolds numbers, has been a cornerstone of closure theories as well as of the most promising recent development in the effort to predict turbulent flows, viz. large eddy simulations. This hypothesis was first advanced by Kolmogorov based on the supposition that turbulent kinetic energy cascades down the scales (up the wave-numbers) of turbulence and that, if the number of these cascade steps is sufficiently large (i.e. the wave-number range is large), then the effects of anisotropies at the large scales are lost in the energy transfer process. Experimental attempts were repeatedly made to verify this fundamental assumption. However, Van Atta has recently suggested that an examination of the scalar and velocity gradient fields is necessary to definitively verify this hypothesis or prove it to be unfounded. Of course, this must be carried out in a flow with a sufficiently high Reynolds number to provide the necessary separation of scales in order unambiguously to provide the possibility of local isotropy at large wave-numbers. An opportunity to use our 12-sensor hot-wire probe to address this issue directly was made available at the 80'x120' wind tunnel at the NASA Ames Research Center, which is normally used for full-scale aircraft tests. An initial report on this high Reynolds number experiment and progress toward its evaluation is presented.

A Historical Perspective on Dynamics Testing at the Langley Research Center

NASA Technical Reports Server (NTRS)

Horta, Lucas G.; Kvaternik, Raymond G.

2000-01-01

The history of structural dynamics testing research over the past four decades at the Langley Research Center of the National Aeronautics and Space Administration is reviewed. Beginning in the early sixties, Langley investigated several scale model and full-scale spacecraft including the NIMBUS and various concepts for Apollo and Viking landers. Langley engineers pioneered the use of scaled models to study the dynamics of launch vehicles including Saturn I, Saturn V, and Titan III. In the seventies, work emphasized the Space Shuttle and advanced test and data analysis methods. In the eighties, the possibility of delivering large structures to orbit by the Space Shuttle shifted focus towards understanding the interaction of flexible space structures with attitude control systems. Although Langley has maintained a tradition of laboratory-based research, some flight experiments were supported. This review emphasizes work that, in some way, advanced the state of knowledge at the time.

A Global Survey of Oceanic Mesoscale Convective Systems in Association with the Large-scale Water Vapor and Vertical Wind Shear

NASA Astrophysics Data System (ADS)

Yuan, J.; Zhan, T.

2017-12-01

Sizes and organizations of mesoscale scale convective systems (MCSs) usually are related to both their precipitation characteristics and anvil productivity, which are crucial but not well-represented in current climate models. This study aims to further our knowledge about MCSs by documenting the relationship between MCSs and their associated large-scale environmental moisture and wind shear in different phases of large-scale convection. A dataset derived from MODIS and AMSR-E and TRMM, CMOPH and ERA-Interim reanalysis are used. Larger and merged systems tend to occur more frequently when the large-scale convection is stronger. At the occurrence time of MCSs, the middle troposphere relative humidity (MRH, 800-400hPa) shows large increases ( 15%) from the suppressed to the active phases. Differences of the MRH across phases appear in a large area and reaches its maximum at 650 850 km away from the center of MCSs. Higher MRH is found within 650 km around the center of merged and large MCSs in all phases. This distance is much larger than the size of any single MCSs. The MRH shows larger spatial gradients around merged MCSs, indicating that moisture tends to cluster around merged systems. Similar spatial differences of MRH appear at all phases 1-3 days before the MCSs occur. In lower troposphere (1000-850hPa), differences in the relative humidity are much smaller than that of MRH. In all phases around all MCSs the oceanic boundary layer is always effectively moisturized (RH>92%). Temporally the lower troposphere relative humidity is dominated by diurnal variations. No clear difference across systems of the wind shear is found when the domain-wide upward motion is dominated. In all cases there are always large low-level (1000-750hPa) wind shear (7-9m/s) and middle level (1000-750hPa) wind shear (11-15m/s) occurring at large distances (>500km) away from MCSs. However, both the low-level and the middle level wind shear closely around the MCSs converge to moderate values of 3-4.2m/s and 5-7m/s, respectively. Indicating that weak or moderate wind shear conditions favor developments of MCSs. Small but systematical differences in wind shear across phases are found. This study provides an observational reference for both cloud resovling or climate models to diagnose and improve their representaions of organized convection.

Life cycles of persistent anomalies. I - Evolution of 500 mb height fields

NASA Technical Reports Server (NTRS)

Dole, Randall M.

1989-01-01

The life cycles of persistent anomalies of the extratropical Northern Hemisphere wintertime circulation are studied, focusing on the typical characteristics of the 500 mb height anomaly and flow patterns accompanying the development and breakdown of large-scale flow anomalies in the eastern North Atlantic and the northern Soviet Union. Following onset, anomaly centers develop and intensify in sequence downstream from the main center, forming a quasi-stationary wavetrain pattern. From development through decay, corresponding positive and negative patterns have similar evolutions.

Experimental program for real gas flow code validation at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

Deiwert, George S.; Strawa, Anthony W.; Sharma, Surendra P.; Park, Chul

1989-01-01

The experimental program for validating real gas hypersonic flow codes at NASA Ames Rsearch Center is described. Ground-based test facilities used include ballistic ranges, shock tubes and shock tunnels, arc jet facilities and heated-air hypersonic wind tunnels. Also included are large-scale computer systems for kinetic theory simulations and benchmark code solutions. Flight tests consist of the Aeroassist Flight Experiment, the Space Shuttle, Project Fire 2, and planetary probes such as Galileo, Pioneer Venus, and PAET.

Final Technical Report - Center for Technology for Advanced Scientific Component Software (TASCS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sussman, Alan

2014-10-21

This is a final technical report for the University of Maryland work in the SciDAC Center for Technology for Advanced Scientific Component Software (TASCS). The Maryland work focused on software tools for coupling parallel software components built using the Common Component Architecture (CCA) APIs. Those tools are based on the Maryland InterComm software framework that has been used in multiple computational science applications to build large-scale simulations of complex physical systems that employ multiple separately developed codes.

Hydrological response of karst systems to large-scale climate variability for different catchments of the French karst observatory network INSU/CNRS SNO KARST

NASA Astrophysics Data System (ADS)

Massei, Nicolas; Labat, David; Jourde, Hervé; Lecoq, Nicolas; Mazzilli, Naomi

2017-04-01

The french karst observatory network SNO KARST is a national initiative from the National Institute for Earth Sciences and Astronomy (INSU) of the National Center for Scientific Research (CNRS). It is also part of the new french research infrastructure for the observation of the critical zone OZCAR. SNO KARST is composed by several karst sites distributed over conterminous France which are located in different physiographic and climatic contexts (Mediterranean, Pyrenean, Jura mountain, western and northwestern shore near the Atlantic or the English Channel). This allows the scientific community to develop advanced research and experiments dedicated to improve understanding of the hydrological functioning of karst catchments. Here we used several sites of SNO KARST in order to assess the hydrological response of karst catchments to long-term variation of large-scale atmospheric circulation. Using NCEP reanalysis products and karst discharge, we analyzed the links between large-scale circulation and karst water resources variability. As karst hydrosystems are highly heterogeneous media, they behave differently across different time-scales : we explore the large-scale/local-scale relationships according to time-scales using a wavelet multiresolution approach of both karst hydrological variables and large-scale climate fields such as sea level pressure (SLP). The different wavelet components of karst discharge in response to the corresponding wavelet component of climate fields are either 1) compared to physico-chemical/geochemical responses at karst springs, or 2) interpreted in terms of hydrological functioning by comparing discharge wavelet components to internal components obtained from precipitation/discharge models using the KARSTMOD conceptual modeling platform of SNO KARST.

Analysis of the ability of large-scale reanalysis data to define Siberian fire danger in preparation for future fire prediction

NASA Astrophysics Data System (ADS)

Soja, Amber; Westberg, David; Stackhouse, Paul, Jr.; McRae, Douglas; Jin, Ji-Zhong; Sukhinin, Anatoly

2010-05-01

Fire is the dominant disturbance that precipitates ecosystem change in boreal regions, and fire is largely under the control of weather and climate. Fire frequency, fire severity, area burned and fire season length are predicted to increase in boreal regions under current climate change scenarios. Therefore, changes in fire regimes have the potential to compel ecological change, moving ecosystems more quickly towards equilibrium with a new climate. The ultimate goal of this research is to assess the viability of large-scale (1°) data to be used to define fire weather danger and fire regimes, so that large-scale data can be confidently used to predict future fire regimes using large-scale fire weather data, like that available from current Intergovernmental Panel on Climate Change (IPCC) climate change scenarios. In this talk, we intent to: (1) evaluate Fire Weather Indices (FWI) derived using reanalysis and interpolated station data; (2) discuss the advantages and disadvantages of using these distinct data sources; and (3) highlight established relationships between large-scale fire weather data, area burned, active fires and ecosystems burned. Specifically, the Canadian Forestry Service (CFS) Fire Weather Index (FWI) will be derived using: (1) NASA Goddard Earth Observing System version 4 (GEOS-4) large-scale reanalysis and NASA Global Precipitation Climatology Project (GPCP) data; and National Climatic Data Center (NCDC) surface station-interpolated data. Requirements of the FWI are local noon surface-level air temperature, relative humidity, wind speed, and daily (noon-noon) rainfall. GEOS-4 reanalysis and NCDC station-interpolated fire weather indices are generally consistent spatially, temporally and quantitatively. Additionally, increased fire activity coincides with increased FWI ratings in both data products. Relationships have been established between large-scale FWI to area burned, fire frequency, ecosystem types, and these can be use to estimate historic and future fire regimes.

Non-invasive Prediction of Pork Loin Tenderness

USDA-ARS?s Scientific Manuscript database

The present experiment was conducted to develop a non-invasive method to predict tenderness of pork loins. Boneless pork loins (n = 901) were evaluated either on line on the loin boning and trimming line of large-scale commercial plants (n = 465) or at the U.S. Meat Animal Research Center abattoir ...

Prediction of Pork Longissimus Lean Color Stability Using VIS/NIR

USDA-ARS?s Scientific Manuscript database

Insufficient case-life is a costly problem facing pork processors. To assess Visible and Near-Infrared (VIS/NIR) spectroscopy as a technology to sort pork loins according to lean color stability, center-cut pork loins (n = 1208) were selected from the boning lines of four large-scale pork processor...

Science Information System in Japan. NIER Occasional Paper 02/83.

ERIC Educational Resources Information Center

Matsumura, Tamiko

This paper describes the development of a proposed Japanese Science Information System (SIS), a nationwide network of research and academic libraries, large-scale computer centers, national research institutes, and other organizations, to be formed for the purpose of sharing information and resources in the natural sciences, technology, the…

Emily Evans | NREL

Science.gov Websites

Evans Emily Evans Project Controller Emily.Evans@nrel.gov | 303-275-3125 Emily joined NREL in 2010 . As a Project Administrator in the Integrated Applications Center, Emily works with project managers and teams to develop and maintain project management excellence on large-scale, multi-year projects

Strain coupling between nitrogen vacancy centers and the mechanical motion of a diamond optomechanical crystal resonator

NASA Astrophysics Data System (ADS)

Cady, J. V.; Lee, K. W.; Ovartchaiyapong, P.; Bleszynski Jayich, A. C.

Several experiments have recently demonstrated coupling between nitrogen vacancy (NV) centers in diamond and mechanical resonators via crystal strain. In the strong coupling regime, such devices could realize applications critical to emerging quantum technologies, including phonon-mediated spin-spin interactions and mechanical cooling with the NV center1. An outstanding challenge for these devices is generating higher strain coupling in high frequency devices while maintaining the excellent coherence properties of the NV center and high mechanical quality factors. As a step toward these objectives, we demonstrate single-crystal diamond optomechanical crystal resonators with embedded NV centers. These devices host highly-confined GHz-scale mechanical modes that are isolated from mechanical clamping losses and generate strain profiles that allow for large strain coupling to NV centers far from noise-inducing surfaces.

Preschool Center Quality and School Readiness: Quality Effects and Variation by Demographic and Child Characteristics

PubMed Central

Keys, Tran D.; Farkas, George; Burchinal, Margaret R.; Duncan, Greg J.; Vandell, Deborah L.; Li, Weilin; Ruzek, Erik A.; Howes, Carollee

2014-01-01

This article examines associations between observed quality in preschool center classrooms for approximately 6,250 three- to five-year-olds and their school readiness skills at kindergarten entry. Secondary analyses were conducted using data from four large-scale studies to estimate the effects of preschool center quality and interactions between quality and demographic characteristics and child entry skills and behaviors. Findings were summarized across studies using meta-analytic methods. Results indicate small, but statistically significant associations for preschool center quality main effects on language and mathematics outcomes with little evidence of moderation by demographic characteristics or child entry skills and behaviors. Preschool center quality was not reliably related to socioemotional outcomes. The authors discuss possible explanations for the small effect sizes and lack of differential effects. PMID:23331043

Excellence in Physics Education Award: SCALE-UP, Student Centered Active Learning Environment with Upside-down Pedagogies

NASA Astrophysics Data System (ADS)

Beichner, Robert

2016-03-01

The Student-Centered Active Learning Environment with Upside-down Pedagogies (SCALE-UP) Project combines curricula and a specially-designed instructional space to enhance learning. SCALE-UP students practice communication and teamwork skills while performing activities that enhance their conceptual understanding and problem solving skills. This can be done with small or large classes and has been implemented at more than 250 institutions. Educational research indicates that students should collaborate on interesting tasks and be deeply involved with the material they are studying. SCALE-UP classtime is spent primarily on ``tangibles'' and ``ponderables''--hands-on measurements/observations and interesting questions. There are also computer simulations (called ``visibles'') and hypothesis-driven labs. Students sit at tables designed to facilitate group interactions. Instructors circulate and engage in Socratic dialogues. The setting looks like a banquet hall, with lively interactions nearly all the time. Impressive learning gains have been measured at institutions across the US and internationally. This talk describes today's students, how lecturing got started, what happens in a SCALE-UP classroom, and how the approach has spread. The SCALE-UP project has greatly benefitted from numerous Grants made by NSF and FIPSE to NCSU and other institutions.

Search for large extra dimensions in dielectron and diphoton production.

PubMed

Abbott, B; Abolins, M; Abramov, V; Acharya, B S; Adams, D L; Adams, M; Alves, G A; Amos, N; Anderson, E W; Baarmand, M M; Babintsev, V V; Babukhadia, L; Baden, A; Baldin, B; Balm, P W; Banerjee, S; Bantly, J; Barberis, E; Baringer, P; Bartlett, J F; Bassler, U; Bean, A; Begel, M; Belyaev, A; Beri, S B; Bernardi, G; Bertram, I; Besson, A; Bezzubov, V A; Bhat, P C; Bhatnagar, V; Bhattacharjee, M; Blazey, G; Blessing, S; Boehnlein, A; Bojko, N I; Borcherding, F; Brandt, A; Breedon, R; Briskin, G; Brock, R; Brooijmans, G; Bross, A; Buchholz, D; Buehler, M; Buescher, V; Burtovoi, V S; Butler, J M; Canelli, F; Carvalho, W; Casey, D; Casilum, Z; Castilla-Valdez, H; Chakraborty, D; Chan, K M; Chekulaev, S V; Cho, D K; Choi, S; Chopra, S; Christenson, J H; Chung, M; Claes, D; Clark, A R; Cochran, J; Coney, L; Connolly, B; Cooper, W E; Coppage, D; Cummings, M A; Cutts, D; Dahl, O I; Davis, G A; Davis, K; De, K; Del Signore, K; Demarteau, M; Demina, R; Demine, P; Denisov, D; Denisov, S P; Desai, S; Diehl, H T; Diesburg, M; Di Loreto, G; Doulas, S; Draper, P; Ducros, Y; Dudko, L V; Duensing, S; Dugad, S R; Dyshkant, A; Edmunds, D; Ellison, J; Elvira, V D; Engelmann, R; Eno, S; Eppley, G; Ermolov, P; Eroshin, O V; Estrada, J; Evans, H; Evdokimov, V N; Fahland, T; Feher, S; Fein, D; Ferbel, T; Fisk, H E; Fisyak, Y; Flattum, E; Fleuret, F; Fortner, M; Frame, K C; Fuess, S; Gallas, E; Galyaev, A N; Gartung, P; Gavrilov, V; Genik, R J; Genser, K; Gerber, C E; Gershtein, Y; Gibbard, B; Gilmartin, R; Ginther, G; Gómez, B; Gómez, G; Goncharov, P I; González Solís, J L; Gordon, H; Goss, L T; Gounder, K; Goussiou, A; Graf, N; Graham, G; Grannis, P D; Green, J A; Greenlee, H; Grinstein, S; Groer, L; Grudberg, P; Grünendahl, S; Gupta, A; Gurzhiev, S N; Gutierrez, G; Gutierrez, P; Hadley, N J; Haggerty, H; Hagopian, S; Hagopian, V; Hahn, K S; Hall, R E; Hanlet, P; Hansen, S; Hauptman, J M; Hays, C; Hebert, C; Hedin, D; Heinson, A P; Heintz, U; Heuring, T; Hirosky, R; Hobbs, J D; Hoeneisen, B; Hoftun, J S; Hou, S; Huang, Y; Ito, A S; Jerger, S A; Jesik, R; Johns, K; Johnson, M; Jonckheere, A; Jones, M; Jöstlein, H; Juste, A; Kahn, S; Kajfasz, E; Karmanov, D; Karmgard, D; Kehoe, R; Kim, S K; Klima, B; Klopfenstein, C; Knuteson, B; Ko, W; Kohli, J M; Kostritskiy, A V; Kotcher, J; Kotwal, A V; Kozelov, A V; Kozlovsky, E A; Krane, J; Krishnaswamy, M R; Krzywdzinski, S; Kubantsev, M; Kuleshov, S; Kulik, Y; Kunori, S; Kuznetsov, V E; Landsberg, G; Leflat, A; Lehner, F; Li, J; Li, Q Z; Lima, J G; Lincoln, D; Linn, S L; Linnemann, J; Lipton, R; Lucotte, A; Lueking, L; Lundstedt, C; Maciel, A K; Madaras, R J; Manankov, V; Mao, H S; Marshall, T; Martin, M I; Martin, R D; Mauritz, K M; May, B; Mayorov, A A; McCarthy, R; McDonald, J; McMahon, T; Melanson, H L; Meng, X C; Merkin, M; Merritt, K W; Miao, C; Miettinen, H; Mihalcea, D; Mincer, A; Mishra, C S; Mokhov, N; Mondal, N K; Montgomery, H E; Moore, R W; Mostafa, M; da Motta, H; Nagy, E; Nang, F; Narain, M; Narasimham, V S; Neal, H A; Negret, J P; Negroni, S; Norman, D; Oesch, L; Oguri, V; Olivier, B; Oshima, N; Padley, P; Pan, L J; Para, A; Parashar, N; Partridge, R; Parua, N; Paterno, M; Patwa, A; Pawlik, B; Perkins, J; Peters, M; Peters, O; Piegaia, R; Piekarz, H; Pope, B G; Popkov, E; Prosper, H B; Protopopescu, S; Qian, J; Quintas, P Z; Raja, R; Rajagopalan, S; Ramberg, E; Rapidis, P A; Reay, N W; Reucroft, S; Rha, J; Rijssenbeek, M; Rockwell, T; Roco, M; Rubinov, P; Ruchti, R; Rutherfoord, J; Santoro, A; Sawyer, L; Schamberger, R D; Schellman, H; Schwartzman, A; Sculli, J; Sen, N; Shabalina, E; Shankar, H C; Shivpuri, R K; Shpakov, D; Shupe, M; Sidwell, R A; Simak, V; Singh, H; Singh, J B; Sirotenko, V; Slattery, P; Smith, E; Smith, R P; Snihur, R; Snow, G R; Snow, J; Snyder, S; Solomon, J; Sorín, V; Sosebee, M; Sotnikova, N; Soustruznik, K; Souza, M; Stanton, N R; Steinbrück, G; Stephens, R W; Stevenson, M L; Stichelbaut, F; Stoker, D; Stolin, V; Stoyanova, D A; Strauss, M; Streets, K; Strovink, M; Stutte, L; Sznajder, A; Taylor, W; Tentindo-Repond, S; Thompson, J; Toback, D; Tripathi, S M; Trippe, T G; Turcot, A S; Tuts, P M; van Gemmeren, P; Vaniev, V; Van Kooten, R; Varelas, N; Volkov, A A; Vorobiev, A P; Wahl, H D; Wang, H; Wang, Z; Warchol, J; Watts, G; Wayne, M; Weerts, H; White, A; White, J T; Whiteson, D; Wightman, J A; Wijngaarden, D A; Willis, S; Wimpenny, S J; Wirjawan, J V; Womersley, J; Wood, D R; Yamada, R; Yamin, P; Yasuda, T; Yip, K; Youssef, S; Yu, J; Yu, Z; Zanabria, M; Zheng, H; Zhou, Z; Zhu, Z H; Zielinski, M; Zieminska, D; Zieminski, A; Zutshi, V; Zverev, E G; Zylberstejn, A

2001-02-12

We report a search for effects of large extra spatial dimensions in pp collisions at a center-of-mass energy of 1.8 TeV with the D0 detector, using events containing a pair of electrons or photons. The data are in good agreement with the expected background and do not exhibit evidence for large extra dimensions. We set the most restrictive lower limits to date, at the 95% C.L. on the effective Planck scale between 1.0 and 1.4 TeV for several formalisms and numbers of extra dimensions.

Direct and inverse energy cascades in a forced rotating turbulence experiment

NASA Astrophysics Data System (ADS)

Campagne, Antoine; Gallet, Basile; Moisy, Frédéric; Cortet, Pierre-Philippe

2014-12-01

We present experimental evidence for a double cascade of kinetic energy in a statistically stationary rotating turbulence experiment. Turbulence is generated by a set of vertical flaps, which continuously injects velocity fluctuations towards the center of a rotating water tank. The energy transfers are evaluated from two-point third-order three-component velocity structure functions, which we measure using stereoscopic particle image velocimetry in the rotating frame. Without global rotation, the energy is transferred from large to small scales, as in classical three-dimensional turbulence. For nonzero rotation rates, the horizontal kinetic energy presents a double cascade: a direct cascade at small horizontal scales and an inverse cascade at large horizontal scales. By contrast, the vertical kinetic energy is always transferred from large to small horizontal scales, a behavior reminiscent of the dynamics of a passive scalar in two-dimensional turbulence. At the largest rotation rate, the flow is nearly two-dimensional, and a pure inverse energy cascade is found for the horizontal energy. To describe the scale-by-scale energy budget, we consider a generalization of the Kármán-Howarth-Monin equation to inhomogeneous turbulent flows, in which the energy input is explicitly described as the advection of turbulent energy from the flaps through the surface of the control volume where the measurements are performed.

Investigation of multilayer domains in large-scale CVD monolayer graphene by optical imaging

NASA Astrophysics Data System (ADS)

Yu, Yuanfang; Li, Zhenzhen; Wang, Wenhui; Guo, Xitao; Jiang, Jie; Nan, Haiyan; Ni, Zhenhua

2017-03-01

CVD graphene is a promising candidate for optoelectronic applications due to its high quality and high yield. However, multi-layer domains could inevitably form at the nucleation centers during the growth. Here, we propose an optical imaging technique to precisely identify the multilayer domains and also the ratio of their coverage in large-scale CVD monolayer graphene. We have also shown that the stacking disorder in twisted bilayer graphene as well as the impurities on the graphene surface could be distinguished by optical imaging. Finally, we investigated the effects of bilayer domains on the optical and electrical properties of CVD graphene, and found that the carrier mobility of CVD graphene is seriously limited by scattering from bilayer domains. Our results could be useful for guiding future optoelectronic applications of large-scale CVD graphene. Project supported by the National Natural Science Foundation of China (Nos. 61422503, 61376104), the Open Research Funds of Key Laboratory of MEMS of Ministry of Education (SEU, China), and the Fundamental Research Funds for the Central Universities.

Large-Scale Advanced Prop-Fan (LAP)

NASA Technical Reports Server (NTRS)

Degeorge, C. L.

1988-01-01

In recent years, considerable attention has been directed toward improving aircraft fuel efficiency. Analytical studies and research with wind tunnel models have demonstrated that the high inherent efficiency of low speed turboprop propulsion systems may now be extended to the Mach .8 flight regime of today's commercial airliners. This can be accomplished with a propeller, employing a large number of thin highly swept blades. The term Prop-Fan has been coined to describe such a propulsion system. In 1983 the NASA-Lewis Research Center contracted with Hamilton Standard to design, build and test a near full scale Prop-Fan, designated the Large Scale Advanced Prop-Fan (LAP). This report provides a detailed description of the LAP program. The assumptions and analytical procedures used in the design of Prop-Fan system components are discussed in detail. The manufacturing techniques used in the fabrication of the Prop-Fan are presented. Each of the tests run during the course of the program are also discussed and the major conclusions derived from them stated.

Introduction: demography and cultural macroevolution.

PubMed

Steele, James; Shennan, Stephen

2009-04-01

The papers in this special issue of Human Biology, which derive from a conference sponsored by the Arts and Humanities Research Council (AHRC) Center for the Evolution of Cultural Diversity, lay some of the foundations for an empirical macroevolutionary analysis of cultural dynamics. Our premise here is that cultural dynamics-including the stability of traditions and the rate of origination of new variants-are influenced by independently occurring demographic processes (population size, structure, and distribution as these vary over time as a result of changes in rates of fertility, mortality, and migration). The contributors focus on three sets of problems relevant to empirical studies of cultural macroevolution: large-scale reconstruction of past population dynamics from archaeological and genetic data; juxtaposition of models and evidence of cultural dynamics using large-scale archaeological and historical data sets; and juxtaposition of models and evidence of cultural dynamics from large-scale linguistic data sets. In this introduction we outline some of the theoretical and methodological issues and briefly summarize the individual contributions.

Large-Scale Low-Boom Inlet Test Overview

NASA Technical Reports Server (NTRS)

Hirt, Stefanie

2011-01-01

This presentation provides a high level overview of the Large-Scale Low-Boom Inlet Test and was presented at the Fundamental Aeronautics 2011 Technical Conference. In October 2010 a low-boom supersonic inlet concept with flow control was tested in the 8'x6' supersonic wind tunnel at NASA Glenn Research Center (GRC). The primary objectives of the test were to evaluate the inlet stability and operability of a large-scale low-boom supersonic inlet concept by acquiring performance and flowfield validation data, as well as evaluate simple, passive, bleedless inlet boundary layer control options. During this effort two models were tested: a dual stream inlet intended to model potential flight hardware and a single stream design to study a zero-degree external cowl angle and to permit surface flow visualization of the vortex generator flow control on the internal centerbody surface. The tests were conducted by a team of researchers from NASA GRC, Gulfstream Aerospace Corporation, University of Illinois at Urbana-Champaign, and the University of Virginia

Interobserver Agreement in Clinical Grading of Vitreous Haze Using Alternative Grading Scales

PubMed Central

Hornbeak, Dana M; Payal, Abhishek; Pistilli, Maxwell; Biswas, Jyotirmay; Ganesh, Sudha K; Gupta, Vishali; Rathinam, Sivakumar R; Davis, Janet L; Kempen, John H

2014-01-01

Purpose To evaluate the reliability of clinical grading of vitreous haze using a new 9-step ordinal scale vs. the existing 6-step ordinal scale. Design Evaluation of Diagnostic Test (interobserver agreement study). Participants 119 consecutive patients (204 uveitic eyes) presenting for uveitis subspecialty care on the study day at one of three large uveitis centers. Methods Five pairs of uveitis specialists clinically graded vitreous haze in the same eyes, one after the other using the same equipment, using the 6- and 9-step scales. Main Outcome Measures Agreement in vitreous haze grade between each pair of specialists was evaluated by the κ statistic (exact agreement and agreement within one or two grades). Results The scales correlated well (Spearman’s ρ=0.84). Exact agreement was modest using both the 6-step and 9-step scales: average κ=0.46 (range 0.28–0.81) and κ=0.40 (range 0.15–0.63), respectively. Within-1-grade agreement was slightly more favorable for the scale with fewer steps, but values were excellent for both scales: κ=0.75 (range 0.66–0.96) and κ=0.62 (range 0.38–0.87), respectively. Within-2-grade agreement for the 9-step scale also was excellent [κ=0.85 (range 0.79–0.92)]. Two-fold more cases were potentially clinical trial eligible based on the 9- than the 6-step scale (p<0.001). Conclusions Both scales are sufficiently reproducible using clinical grading for clinical and research use with the appropriate threshold (a ≥2 and ≥3 step differences for the 6-step and 9-step scales respectively). The results suggest that more eyes are likely to meet eligibility criteria for trials using the 9-step scale. The 9-step scale appears to have higher reproducibility with Reading Center grading than clinical grading, suggesting Reading Center grading may be preferable for clinical trials. PMID:24697913

Aft-End Flow of a Large-Scale Lifting Body During Free-Flight Tests

NASA Technical Reports Server (NTRS)

Banks, Daniel W.; Fisher, David F.

2006-01-01

Free-flight tests of a large-scale lifting-body configuration, the X-38 aircraft, were conducted using tufts to characterize the flow on the aft end, specifically in the inboard region of the vertical fins. Pressure data was collected on the fins and base. Flow direction and movement were correlated with surface pressure and flight condition. The X-38 was conceived to be a rescue vehicle for the International Space Station. The vehicle shape was derived from the U.S. Air Force X-24 lifting body. Free-flight tests of the X-38 configuration were conducted at the NASA Dryden Flight Research Center at Edwards Air Force Base, California from 1997 to 2001.

NASA Space Engineering Research Center for VLSI systems design

NASA Technical Reports Server (NTRS)

1991-01-01

This annual review reports the center's activities and findings on very large scale integration (VLSI) systems design for 1990, including project status, financial support, publications, the NASA Space Engineering Research Center (SERC) Symposium on VLSI Design, research results, and outreach programs. Processor chips completed or under development are listed. Research results summarized include a design technique to harden complementary metal oxide semiconductors (CMOS) memory circuits against single event upset (SEU); improved circuit design procedures; and advances in computer aided design (CAD), communications, computer architectures, and reliability design. Also described is a high school teacher program that exposes teachers to the fundamentals of digital logic design.

Relation of major volcanic center concentration on Venus to global tectonic patterns

NASA Technical Reports Server (NTRS)

Crumpler, L. S.; Head, James W.; Aubele, Jayne C.

1993-01-01

Global analysis of Magellan image data indicates that a major concentration of volcanic centers covering about 40 percent of the surface of Venus occurs between the Beta, Atla, and Themis regions. Associated with this enhanced concentration are geological characteristics commonly interpreted as rifting and mantle upwelling. Interconnected low plains in an annulus around this concentration are characterized by crustal shortening and infrequent volcanic centers that may represent sites of mantle return flow and net downwelling. Together, these observations suggest the existence of relatively simple, large-scale patterns of mantle circulation similar to those associated with concentrations of intraplate volcanism on earth.

Wing force and surface pressure data from a hover test of a 0.658-scale V-22 rotor and wing

NASA Technical Reports Server (NTRS)

Felker, Fort F.; Shinoda, Patrick R.; Heffernan, Ruth M.; Sheehy, Hugh F.

1990-01-01

A hover test of a 0.658-scale V-22 rotor and wing was conducted in the 40 x 80 foot wind tunnel at Ames Research Center. The principal objective of the test was to measure the surface pressures and total download on a large scale V-22 wing in hover. The test configuration consisted of a single rotor and semispan wing on independent balance systems. A large image plane was used to represent the aircraft plane of symmetry. Wing flap angles ranging from 45 to 90 degrees were examined. Data were acquired for both directions of the rotor rotation relative to the wing. Steady and unsteady wing surface pressures, total wing forces, and rotor performance data are presented for all of the configurations that were tested.

Plot-scale field experiment of surface hydrologic processes with EOS implications

NASA Technical Reports Server (NTRS)

Laymon, Charles A.; Macari, Emir J.; Costes, Nicholas C.

1992-01-01

Plot-scale hydrologic field studies were initiated at NASA Marshall Space Flight Center to a) investigate the spatial and temporal variability of surface and subsurface hydrologic processes, particularly as affected by vegetation, and b) develop experimental techniques and associated instrumentation methodology to study hydrologic processes at increasingly large spatial scales. About 150 instruments, most of which are remotely operated, have been installed at the field site to monitor ground atmospheric conditions, precipitation, interception, soil-water status, and energy flux. This paper describes the nature of the field experiment, instrumentation and sampling rationale, and presents preliminary findings.

The Transgenic RNAi Project at Harvard Medical School: Resources and Validation

PubMed Central

Perkins, Lizabeth A.; Holderbaum, Laura; Tao, Rong; Hu, Yanhui; Sopko, Richelle; McCall, Kim; Yang-Zhou, Donghui; Flockhart, Ian; Binari, Richard; Shim, Hye-Seok; Miller, Audrey; Housden, Amy; Foos, Marianna; Randkelv, Sakara; Kelley, Colleen; Namgyal, Pema; Villalta, Christians; Liu, Lu-Ping; Jiang, Xia; Huan-Huan, Qiao; Wang, Xia; Fujiyama, Asao; Toyoda, Atsushi; Ayers, Kathleen; Blum, Allison; Czech, Benjamin; Neumuller, Ralph; Yan, Dong; Cavallaro, Amanda; Hibbard, Karen; Hall, Don; Cooley, Lynn; Hannon, Gregory J.; Lehmann, Ruth; Parks, Annette; Mohr, Stephanie E.; Ueda, Ryu; Kondo, Shu; Ni, Jian-Quan; Perrimon, Norbert

2015-01-01

To facilitate large-scale functional studies in Drosophila, the Drosophila Transgenic RNAi Project (TRiP) at Harvard Medical School (HMS) was established along with several goals: developing efficient vectors for RNAi that work in all tissues, generating a genome-scale collection of RNAi stocks with input from the community, distributing the lines as they are generated through existing stock centers, validating as many lines as possible using RT–qPCR and phenotypic analyses, and developing tools and web resources for identifying RNAi lines and retrieving existing information on their quality. With these goals in mind, here we describe in detail the various tools we developed and the status of the collection, which is currently composed of 11,491 lines and covering 71% of Drosophila genes. Data on the characterization of the lines either by RT–qPCR or phenotype is available on a dedicated website, the RNAi Stock Validation and Phenotypes Project (RSVP, http://www.flyrnai.org/RSVP.html), and stocks are available from three stock centers, the Bloomington Drosophila Stock Center (United States), National Institute of Genetics (Japan), and TsingHua Fly Center (China). PMID:26320097

Micro-Level Adaptation, Macro-Level Selection, and the Dynamics of Market Partitioning

PubMed Central

García-Díaz, César; van Witteloostuijn, Arjen; Péli, Gábor

2015-01-01

This paper provides a micro-foundation for dual market structure formation through partitioning processes in marketplaces by developing a computational model of interacting economic agents. We propose an agent-based modeling approach, where firms are adaptive and profit-seeking agents entering into and exiting from the market according to their (lack of) profitability. Our firms are characterized by large and small sunk costs, respectively. They locate their offerings along a unimodal demand distribution over a one-dimensional product variety, with the distribution peak constituting the center and the tails standing for the peripheries. We found that large firms may first advance toward the most abundant demand spot, the market center, and release peripheral positions as predicted by extant dual market explanations. However, we also observed that large firms may then move back toward the market fringes to reduce competitive niche overlap in the center, triggering nonlinear resource occupation behavior. Novel results indicate that resource release dynamics depend on firm-level adaptive capabilities, and that a minimum scale of production for low sunk cost firms is key to the formation of the dual structure. PMID:26656107

Micro-Level Adaptation, Macro-Level Selection, and the Dynamics of Market Partitioning.

PubMed

García-Díaz, César; van Witteloostuijn, Arjen; Péli, Gábor

2015-01-01

This paper provides a micro-foundation for dual market structure formation through partitioning processes in marketplaces by developing a computational model of interacting economic agents. We propose an agent-based modeling approach, where firms are adaptive and profit-seeking agents entering into and exiting from the market according to their (lack of) profitability. Our firms are characterized by large and small sunk costs, respectively. They locate their offerings along a unimodal demand distribution over a one-dimensional product variety, with the distribution peak constituting the center and the tails standing for the peripheries. We found that large firms may first advance toward the most abundant demand spot, the market center, and release peripheral positions as predicted by extant dual market explanations. However, we also observed that large firms may then move back toward the market fringes to reduce competitive niche overlap in the center, triggering nonlinear resource occupation behavior. Novel results indicate that resource release dynamics depend on firm-level adaptive capabilities, and that a minimum scale of production for low sunk cost firms is key to the formation of the dual structure.

Validation of large-scale, monochromatic UV disinfection systems for drinking water using dyed microspheres.

PubMed

Blatchley, E R; Shen, C; Scheible, O K; Robinson, J P; Ragheb, K; Bergstrom, D E; Rokjer, D

2008-02-01

Dyed microspheres have been developed as a new method for validation of ultraviolet (UV) reactor systems. When properly applied, dyed microspheres allow measurement of the UV dose distribution delivered by a photochemical reactor for a given operating condition. Prior to this research, dyed microspheres had only been applied to a bench-scale UV reactor. The goal of this research was to extend the application of dyed microspheres to large-scale reactors. Dyed microsphere tests were conducted on two prototype large-scale UV reactors at the UV Validation and Research Center of New York (UV Center) in Johnstown, NY. All microsphere tests were conducted under conditions that had been used previously in biodosimetry experiments involving two challenge bacteriophage: MS2 and Qbeta. Numerical simulations based on computational fluid dynamics and irradiance field modeling were also performed for the same set of operating conditions used in the microspheres assays. Microsphere tests on the first reactor illustrated difficulties in sample collection and discrimination of microspheres against ambient particles. Changes in sample collection and work-up were implemented in tests conducted on the second reactor that allowed for improvements in microsphere capture and discrimination against the background. Under these conditions, estimates of the UV dose distribution from the microspheres assay were consistent with numerical simulations and the results of biodosimetry, using both challenge organisms. The combined application of dyed microspheres, biodosimetry, and numerical simulation offers the potential to provide a more in-depth description of reactor performance than any of these methods individually, or in combination. This approach also has the potential to substantially reduce uncertainties in reactor validation, thereby leading to better understanding of reactor performance, improvements in reactor design, and decreases in reactor capital and operating costs.

Recognising Axionic Dark Matter by Compton and de-Broglie Scale Modulation of Pulsar Timing

NASA Astrophysics Data System (ADS)

De Martino, Ivan; Broadhurst, Tom; Tye, S.-H. Henry; Chiueh, Tzihong; Schive, Hsi-Yu; Lazkoz, Ruth

2017-11-01

Light Axionic Dark Matter, motivated by string theory, is increasingly favored for the "no-WIMP era". Galaxy formation is suppressed below a Jeans scale, of ≃ 10^8 M_⊙ by setting the axion mass to, m_B ˜ 10^{-22}eV, and the large dark cores of dwarf galaxies are explained as solitons on the de-Broglie scale. This is persuasive, but detection of the inherent scalar field oscillation at the Compton frequency, ω_B= (2.5 months)^{-1}(m_B/10^{-22}eV), would be definitive. By evolving the coupled Schrödinger-Poisson equation for a Bose-Einstein condensate, we predict the dark matter is fully modulated by de-Broglie interference, with a dense soliton core of size ≃ 150pc, at the Galactic center. The oscillating field pressure induces General Relativistic time dilation in proportion to the local dark matter density and pulsars within this dense core have detectably large timing residuals, of ≃ 400nsec/(m_B/10^{-22}eV). This is encouraging as many new pulsars should be discovered near the Galactic center with planned radio surveys. More generally, over the whole Galaxy, differences in dark matter density between pairs of pulsars imprints a pairwise Galactocentric signature that can be distinguished from an isotropic gravitational wave background.

Measurement of integrated luminosity and center-of-mass energy of data taken by BESIII at

NASA Astrophysics Data System (ADS)

Ablikim, M.; Achasov, M. N.; Ahmed, S.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, S.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Farinelli, R.; Fava, L.; Fedorov, O.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, R. P.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Y.; Huang, Z. L.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kupsc, A.; Küuhn, W.; Lange, J. S.; Lara, M.; Larin, P.; Leithoff, H.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Y. B.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Y. Y.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Long, Y. F.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Musiol, P.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Shi, M.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, W.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. N.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; (BESIII Collaboration

2017-11-01

To study the nature of the state Y (2175), a dedicated data set of e+e- collision data was collected at the center-of-mass energy of 2.125 GeV with the BESIII detector at the BEPCII collider. By analyzing large-angle Bhabha scattering events, the integrated luminosity of this data set is determined to be 108.49±0.02±0.85 pb-1, where the first uncertainty is statistical and the second one is systematic. In addition, the center-of-mass energy of the data set is determined with radiative dimuon events to be 2126.55±0.03±0.85 MeV, where the first uncertainty is statistical and the second one is systematic. Supported in part by National Key Basic Research Program of China (2015CB856700), National Natural Science Foundation of China (NSFC) (11235011, 11322544, 11335008, 11425524, 11635010, 11675184, 11735014), the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; the CAS Center for Excellence in Particle Physics (CCEPP); the Collaborative Innovation Center for Particles and Interactions (CICPI); Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (U1232201, U1332201, U1532257, U1532258), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS; National 1000 Talents Program of China; INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology; German Research Foundation DFG (Collaborative Research Center CRC 1044, FOR 2359), Istituto Nazionale di Fisica Nucleare, Italy; Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03), Ministry of Development of Turkey (DPT2006K-120470), National Natural Science Foundation of China (NSFC) (11505010), The Swedish Resarch Council; U. S. Department of Energy (DE-FG02-05ER41374, DE-SC-0010118, DE-SC-0010504, DE-SC-0012069), U.S. National Science Foundation; University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0)

Large-Area Subwavelength Aperture Arrays Fabricated Using Nanoimprint Lithography

DOE PAGES

Skinner, J. L.; Hunter, L. L.; Talin, A. A.; ...

2008-07-29

In this paper, we report on the fabrication and characterization of large-area 2-D square arrays of subwavelength holes in Ag and Al films. Fabrication is based on thermal nanoimprint lithography and metal evaporation, without the need for etching, and is compatible with low-cost, large-scale production. Reflectance spectra for these arrays display an intensity minimum whose amplitude, center wavelength, and line width depend on the geometry of the array and the reflectivity of the metal film. By placing various fluids in contact with the subwavelength aperture arrays, we observe that the center wavelength of the reflectance minimum varies linearly with themore » refractive index of the fluid with a sensitivity of over 500 nm per refractive index unit. Lastly, the surface plasmon theory is used to predict sensitivities to refractive index change with accuracies better than 0.5%.« less

Lectures on algebraic system theory: Linear systems over rings

NASA Technical Reports Server (NTRS)

Kamen, E. W.

1978-01-01

The presentation centers on four classes of systems that can be treated as linear systems over a ring. These are: (1) discrete-time systems over a ring of scalars such as the integers; (2) continuous-time systems containing time delays; (3) large-scale discrete-time systems; and (4) time-varying discrete-time systems.

Effective CPD on a Large Scale: Examining the Development of Multipliers

ERIC Educational Resources Information Center

Roesken-Winter, Bettina; Schüler, Sven; Stahnke, Rebekka; Blömeke, Sigrid

2015-01-01

Much research has been conducted on exploring teacher learning and constituting Continuous Professional Development (CPD) designs for teachers. Yet, little is known about appropriate design principles of CPD for teacher trainers/multipliers who in turn are supposed to provide CPD for teachers. The German Center for Mathematics Teacher Education…

1.5 MW turbine installation at NREL's NWTC on Aug. 21

ScienceCinema

None

2017-12-27

Generating 20 percent of the nation's electricity from clean wind resources will require more and bigger wind turbines. NREL is installing two large wind turbines at the National Wind Technology Center to examine some of the industry's largest machines and address issues to expand wind energy on a commercial scale.

Studies in Environment--Volume III: Pollution and the Municipality.

ERIC Educational Resources Information Center

Cooper, Pamela C.; And Others

Recent studies have focused attention on the fact that residents of inner-city neighborhoods are subject to greater amounts of pollutants than are other neighborhoods of large cities. In this study, the premise is set forth and investigated at the metropolitan scale, seeking to discover differences of impact between the center city and its…

Network-based approaches to climate knowledge discovery

NASA Astrophysics Data System (ADS)

Budich, Reinhard; Nyberg, Per; Weigel, Tobias

2011-11-01

Climate Knowledge Discovery Workshop; Hamburg, Germany, 30 March to 1 April 2011 Do complex networks combined with semantic Web technologies offer the next generation of solutions in climate science? To address this question, a first Climate Knowledge Discovery (CKD) Workshop, hosted by the German Climate Computing Center (Deutsches Klimarechenzentrum (DKRZ)), brought together climate and computer scientists from major American and European laboratories, data centers, and universities, as well as representatives from industry, the broader academic community, and the semantic Web communities. The participants, representing six countries, were concerned with large-scale Earth system modeling and computational data analysis. The motivation for the meeting was the growing problem that climate scientists generate data faster than it can be interpreted and the need to prepare for further exponential data increases. Current analysis approaches are focused primarily on traditional methods, which are best suited for large-scale phenomena and coarse-resolution data sets. The workshop focused on the open discussion of ideas and technologies to provide the next generation of solutions to cope with the increasing data volumes in climate science.

Search and rescue response to a large-scale rockfall disaster.

PubMed

Procter, Emily; Strapazzon, Giacomo; Balkenhol, Karla; Fop, Ernst; Faggionato, Alessandro; Mayr, Karl; Falk, Markus; Brugger, Hermann

2015-03-01

To describe the prehospital management and safety of search and rescue (SAR) teams involved in a large-scale rockfall disaster and monitor the acute and chronic health effects on personnel with severe dolomitic dust exposure. SAR personnel underwent on-site medical screening and lung function testing 3 months and 3 years after the event. The emergency dispatch center was responsible for central coordination of resources. One hundred fifty SAR members from multidisciplinary air- and ground-based teams as well as geotechnical experts were dispatched to a provisionary operation center. Acute exposure to dolomite dust with detectable silicon and magnesium concentrations was not associated with (sub)acute or chronic sequelae or a clinically significant impairment in lung function in exposed personnel. The risk for personnel involved in mountain SAR operations is rarely reported and not easily investigated or quantified. This case exemplifies the importance of a multiskilled team and additional considerations for prehospital management during natural hazard events. Safety plans should include compulsory protective measures and medical monitoring of personnel. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

Performing a Large-Scale Modal Test on the B2 Stand Crane at NASA's Stennis Space Center

NASA Technical Reports Server (NTRS)

Stasiunas, Eric C.; Parks, Russel A.; Sontag, Brendan D.

2018-01-01

A modal test of NASA's Space Launch System (SLS) Core Stage is scheduled to occur at the Stennis Space Center B2 test stand. A derrick crane with a 150-ft long boom, located at the top of the stand, will be used to suspend the Core Stage in order to achieve defined boundary conditions. During this suspended modal test, it is expected that dynamic coupling will occur between the crane and the Core Stage. Therefore, a separate modal test was performed on the B2 crane itself, in order to evaluate the varying dynamic characteristics and correlate math models of the crane. Performing a modal test on such a massive structure was challenging and required creative test setup and procedures, including implementing both AC and DC accelerometers, and performing both classical hammer and operational modal analysis. This paper describes the logistics required to perform this large-scale test, as well as details of the test setup, the modal test methods used, and an overview and application of the results.

Performing a Large-Scale Modal Test on the B2 Stand Crane at NASA's Stennis Space Center

NASA Technical Reports Server (NTRS)

Stasiunas, Eric C.; Parks, Russel A.

2018-01-01

A modal test of NASA’s Space Launch System (SLS) Core Stage is scheduled to occur prior to propulsion system verification testing at the Stennis Space Center B2 test stand. A derrick crane with a 180-ft long boom, located at the top of the stand, will be used to suspend the Core Stage in order to achieve defined boundary conditions. During this suspended modal test, it is expected that dynamic coupling will occur between the crane and the Core Stage. Therefore, a separate modal test was performed on the B2 crane itself, in order to evaluate the varying dynamic characteristics and correlate math models of the crane. Performing a modal test on such a massive structure was challenging and required creative test setup and procedures, including implementing both AC and DC accelerometers, and performing both classical hammer and operational modal analysis. This paper describes the logistics required to perform this large-scale test, as well as details of the test setup, the modal test methods used, and an overview of the results.

Auxiliary basis expansions for large-scale electronic structure calculations.

PubMed

Jung, Yousung; Sodt, Alex; Gill, Peter M W; Head-Gordon, Martin

2005-05-10

One way to reduce the computational cost of electronic structure calculations is to use auxiliary basis expansions to approximate four-center integrals in terms of two- and three-center integrals, usually by using the variationally optimum Coulomb metric to determine the expansion coefficients. However, the long-range decay behavior of the auxiliary basis expansion coefficients has not been characterized. We find that this decay can be surprisingly slow. Numerical experiments on linear alkanes and a toy model both show that the decay can be as slow as 1/r in the distance between the auxiliary function and the fitted charge distribution. The Coulomb metric fitting equations also involve divergent matrix elements for extended systems treated with periodic boundary conditions. An attenuated Coulomb metric that is short-range can eliminate these oddities without substantially degrading calculated relative energies. The sparsity of the fit coefficients is assessed on simple hydrocarbon molecules and shows quite early onset of linear growth in the number of significant coefficients with system size using the attenuated Coulomb metric. Hence it is possible to design linear scaling auxiliary basis methods without additional approximations to treat large systems.

Effect of oxygen plasma and thermal oxidation on shallow nitrogen-vacancy centers in diamond

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, M.; Rugar, D., E-mail: rugar@us.ibm.com; Center for Probing the Nanoscale, Stanford University, Stanford, California 94305

2014-07-28

We investigate the effect of two different surface treatments on shallow nitrogen-vacancy (NV) centers in diamond. Short duration oxygen plasma exposure is found to damage near-surface NV centers, resulting in their disappearance in fluorescence images. Subsequent annealing creates large numbers of new NV centers, attributed to plasma-induced vacancy creation. By tracking individual NV centers during thermal oxidation, we show that oxidation at 550 °C results in modest improvement of spin coherence. Higher temperature oxidations correlate with gradual decline in spin coherence and eventual instability of NV centers before ultimate disappearance. This is indicative of a reduction of the NV-to-surface distance duemore » to oxidative etching. Thermal oxidation can offer controlled access to near-surface NV spins at the nanometer scale, an important requirement for many applications of NV-based nanomagnetometry.« less

An increase in aerosol burden due to the land-sea warming contrast

NASA Astrophysics Data System (ADS)

Hassan, T.; Allen, R.; Randles, C. A.

2017-12-01

Climate models simulate an increase in most aerosol species in response to warming, particularly over the tropics and Northern Hemisphere midlatitudes. This increase in aerosol burden is related to a decrease in wet removal, primarily due to reduced large-scale precipitation. Here, we show that the increase in aerosol burden, and the decrease in large-scale precipitation, is related to a robust climate change phenomenon—the land/sea warming contrast. Idealized simulations with two state of the art climate models, the National Center for Atmospheric Research Community Atmosphere Model version 5 (NCAR CAM5) and the Geophysical Fluid Dynamics Laboratory Atmospheric Model 3 (GFDL AM3), show that muting the land-sea warming contrast negates the increase in aerosol burden under warming. This is related to smaller decreases in near-surface relative humidity over land, and in turn, smaller decreases in large-scale precipitation over land—especially in the NH midlatitudes. Furthermore, additional idealized simulations with an enhanced land/sea warming contrast lead to the opposite result—larger decreases in relative humidity over land, larger decreases in large-scale precipitation, and larger increases in aerosol burden. Our results, which relate the increase in aerosol burden to the robust climate projection of enhanced land warming, adds confidence that a warmer world will be associated with a larger aerosol burden.

Large-scale Vertical Motions, Intensity Change and Precipitation Associated with Land falling Hurricane Katrina over the Gulf of Mexico

NASA Astrophysics Data System (ADS)

Reddy, S. R.; Kwembe, T.; Zhang, Z.

2016-12-01

We investigated the possible relationship between the large- scale heat fluxes and intensity change associated with the landfall of Hurricane Katrina. After reaching the category 5 intensity on August 28th , 2005 over the central Gulf of Mexico, Katrina weekend to category 3 before making landfall (August 29th , 2005) on the Louisiana coast with the maximum sustained winds of over 110 knots. We also examined the vertical motions associated with the intensity change of the hurricane. The data for Convective Available Potential Energy for water vapor (CAPE), sea level pressure and wind speed were obtained from the Atmospheric Soundings, and NOAA National Hurricane Center (NHC), respectively for the period August 24 to September 3, 2005. We also computed vertical motions using CAPE values. The study showed that the large-scale heat fluxes reached maximum (7960W/m2) with the central pressure 905mb. The Convective Available Potential Energy and the vertical motions peaked 3-5 days before landfall. The large atmospheric vertical motions associated with the land falling hurricane Katrina produced severe weather including thunderstorm, tornadoes, storm surge and floods Numerical model (WRF/ARW) with data assimilations have been used for this research to investigate the model's performances on hurricane tracks and intensities associated with the hurricane Katrina, which began to strengthen until reaching Category 5 on 28 August 2005. The model was run on a doubly nested domain centered over the central Gulf of Mexico, with grid spacing of 90 km and 30 km for 6 hr periods, from August 28th to August 30th. The model output was compared with the observations and is capable of simulating the surface features, intensity change and track associated with hurricane Katrina.

Investigation of Hydrological Response of Three Identical Artificial Hillslopes at the Landscape Evolution Observatory

NASA Astrophysics Data System (ADS)

Matos, K.; Alves Meira Neto, A.; Troch, P. A. A.; Volkmann, T.

2017-12-01

Hydrological processes at the hillslope scale are complex and heterogeneous, but monitoring hillslopes with a large number of sensors or replicate experimental designs is rarely feasible. The Landscape Evolution Observatory (LEO) at Biosphere 2 consists of three replicated, large (330 m2) artificial hillslopes (East, Center and West) packed with 1-m depth of initially homogeneous, basaltic soil. Each landscape contains a spatially dense network of sensors capable of resolving meter-scale lateral heterogeneity and sub-meter scale vertical heterogeneity in moisture content and water potential, as well as the hillslope-integrated water balance components. A sophisticated irrigation system allows performing controlled forcing experiments. The three hillslopes are thought to be nearly identical, however recent data showed significant differences in discharge and storage behavior. A 45-day periodic-steady-state tracer experiment was conducted in November and December of 2016, where a 3.5-day long, identical irrigation sequence was repeated 15 times. Each sequence's rainfall, runoff, and storage dynamics were recorded, and distributed moisture characteristics were derived using paired moisture content and matric potential data from 496 positions in each hillslope. In order to understand why the three hillslopes behave hydrologically different, we analyzed soil water retention characteristics at various scales ranging from individually paired moisture and matric potential to whole-hillslope soil water retention characteristics. The results confirm the distinct hydrological behavior between the three hillslopes. The East and West hillslopes behave more similar with respect to the release of water. In contrast, the East and Center hillslopes are more similar with respect to their storage behavior. The differences in hillslope behavior arising from three identically built hillslopes are a surprising and beneficial opportunity to explore how differences in small-scale heterogeneity can impact hydrological dynamics at the hillslope scale.

Distribution of guidance models for cardiac resynchronization therapy in the setting of multi-center clinical trials

NASA Astrophysics Data System (ADS)

Rajchl, Martin; Abhari, Kamyar; Stirrat, John; Ukwatta, Eranga; Cantor, Diego; Li, Feng P.; Peters, Terry M.; White, James A.

2014-03-01

Multi-center trials provide the unique ability to investigate novel techniques across a range of geographical sites with sufficient statistical power, the inclusion of multiple operators determining feasibility under a wider array of clinical environments and work-flows. For this purpose, we introduce a new means of distributing pre-procedural cardiac models for image-guided interventions across a large scale multi-center trial. In this method, a single core facility is responsible for image processing, employing a novel web-based interface for model visualization and distribution. The requirements for such an interface, being WebGL-based, are minimal and well within the realms of accessibility for participating centers. We then demonstrate the accuracy of our approach using a single-center pacemaker lead implantation trial with generic planning models.

Estimated allele substitution effects underlying genomic evaluation models depend on the scaling of allele counts.

PubMed

Bouwman, Aniek C; Hayes, Ben J; Calus, Mario P L

2017-10-30

Genomic evaluation is used to predict direct genomic values (DGV) for selection candidates in breeding programs, but also to estimate allele substitution effects (ASE) of single nucleotide polymorphisms (SNPs). Scaling of allele counts influences the estimated ASE, because scaling of allele counts results in less shrinkage towards the mean for low minor allele frequency (MAF) variants. Scaling may become relevant for estimating ASE as more low MAF variants will be used in genomic evaluations. We show the impact of scaling on estimates of ASE using real data and a theoretical framework, and in terms of power, model fit and predictive performance. In a dairy cattle dataset with 630 K SNP genotypes, the correlation between DGV for stature from a random regression model using centered allele counts (RRc) and centered and scaled allele counts (RRcs) was 0.9988, whereas the overall correlation between ASE using RRc and RRcs was 0.27. The main difference in ASE between both methods was found for SNPs with a MAF lower than 0.01. Both the ratio (ASE from RRcs/ASE from RRc) and the regression coefficient (regression of ASE from RRcs on ASE from RRc) were much higher than 1 for low MAF SNPs. Derived equations showed that scenarios with a high heritability, a large number of individuals and a small number of variants have lower ratios between ASE from RRc and RRcs. We also investigated the optimal scaling parameter [from - 1 (RRcs) to 0 (RRc) in steps of 0.1] in the bovine stature dataset. We found that the log-likelihood was maximized with a scaling parameter of - 0.8, while the mean squared error of prediction was minimized with a scaling parameter of - 1, i.e., RRcs. Large differences in estimated ASE were observed for low MAF SNPs when allele counts were scaled or not scaled because there is less shrinkage towards the mean for scaled allele counts. We derived a theoretical framework that shows that the difference in ASE due to shrinkage is heavily influenced by the power of the data. Increasing the power results in smaller differences in ASE whether allele counts are scaled or not.

An Upper Limit on the Mass of a Central Black Hole in the Large Magellanic Cloud from the Stellar Rotation Field

NASA Astrophysics Data System (ADS)

Boyce, H.; Lützgendorf, N.; van der Marel, R. P.; Baumgardt, H.; Kissler-Patig, M.; Neumayer, N.; de Zeeuw, P. T.

2017-09-01

We constrain the possible presence of a central black hole (BH) in the center of the Large Magellanic Cloud. This requires spectroscopic measurements over an area of the order of a square degree, due to the poorly known position of the kinematic center. Such measurements are now possible with the impressive field of view of the Multi Unit Spectroscopic Explorer (MUSE) on the ESO Very Large Telescope. We used the Calcium Triplet (˜850 nm) spectral lines in many short-exposure MUSE pointings to create a two-dimensional integrated-light line-of-sight velocity map from the ˜ {10}8 individual spectra, taking care to identify and remove Galactic foreground populations. The data reveal a clear velocity gradient at an unprecedented spatial resolution of 1 arcmin2. We fit kinematic models to arrive at a 3σ upper-mass limit of {10}7.1 {M}⊙ for any central BH—consistent with the known scaling relations for supermassive black holes and their host systems. This adds to the growing body of knowledge on the presence of BHs in low-mass and dwarf galaxies, and their scaling relations with host-galaxy properties, which can shed light on theories of BH growth and host system interaction.

Gravity Anomalies

NASA Image and Video Library

2015-04-15

Analysis of radio tracking data have enabled maps of the gravity field of Mercury to be derived. In this image, overlain on a mosaic obtained by MESSENGER's Mercury Dual Imaging System and illuminated with a shape model determined from stereo-photoclinometry, Mercury's gravity anomalies are depicted in colors. Red tones indicate mass concentrations, centered on the Caloris basin (center) and the Sobkou region (right limb). Such large-scale gravitational anomalies are signatures of subsurface structure and evolution. The north pole is near the top of the sunlit area in this view. http://photojournal.jpl.nasa.gov/catalog/PIA19285

Cruise noise of the 2/9th scale model of the Large-scale Advanced Propfan (LAP) propeller, SR-7A

NASA Technical Reports Server (NTRS)

Dittmar, James H.; Stang, David B.

1987-01-01

Noise data on the Large-scale Advanced Propfan (LAP) propeller model SR-7A were taken in the NASA Lewis Research Center 8 x 6 foot Wind Tunnel. The maximum blade passing tone noise first rises with increasing helical tip Mach number to a peak level, then remains the same or decreases from its peak level when going to higher helical tip Mach numbers. This trend was observed for operation at both constant advance ratio and approximately equal thrust. This noise reduction or, leveling out at high helical tip Mach numbers, points to the use of higher propeller tip speeds as a possible method to limit airplane cabin noise while maintaining high flight speed and efficiency. Projections of the tunnel model data are made to the full scale LAP propeller mounted on the test bed aircraft and compared with predictions. The prediction method is found to be somewhat conservative in that it slightly overpredicts the projected model data at the peak.

Cruise noise of the 2/9 scale model of the Large-scale Advanced Propfan (LAP) propeller, SR-7A

NASA Technical Reports Server (NTRS)

Dittmar, James H.; Stang, David B.

1987-01-01

Noise data on the Large-scale Advanced Propfan (LAP) propeller model SR-7A were taken in the NASA Lewis Research Center 8 x 6 foot Wind Tunnel. The maximum blade passing tone noise first rises with increasing helical tip Mach number to a peak level, then remains the same or decreases from its peak level when going to higher helical tip Mach numbers. This trend was observed for operation at both constant advance ratio and approximately equal thrust. This noise reduction or, leveling out at high helical tip Mach numbers, points to the use of higher propeller tip speeds as a possible method to limit airplane cabin noise while maintaining high flight speed and efficiency. Projections of the tunnel model data are made to the full scale LAP propeller mounted on the test bed aircraft and compared with predictions. The prediction method is found to be somewhat conservative in that it slightly overpredicts the projected model data at the peak.

Characterizing the Severe Turbulence Environments Associated With Commercial Aviation Accidents. Part 1; 44 Case Study Synoptic Observational Analyses

NASA Technical Reports Server (NTRS)

Kaplan, Michael L.; Huffman, Allan W.; Lux, Kevin M.; Charney, Joseph J.; Riordan, Allan J.; Lin, Yuh-Lang; Proctor, Fred H. (Technical Monitor)

2002-01-01

A 44 case study analysis of the large-scale atmospheric structure associated with development of accident-producing aircraft turbulence is described. Categorization is a function of the accident location, altitude, time of year, time of day, and the turbulence category, which classifies disturbances. National Centers for Environmental Prediction Reanalyses data sets and satellite imagery are employed to diagnose synoptic scale predictor fields associated with the large-scale environment preceding severe turbulence. These analyses indicate a predominance of severe accident-producing turbulence within the entrance region of a jet stream at the synoptic scale. Typically, a flow curvature region is just upstream within the jet entrance region, convection is within 100 km of the accident, vertical motion is upward, absolute vorticity is low, vertical wind shear is increasing, and horizontal cold advection is substantial. The most consistent predictor is upstream flow curvature and nearby convection is the second most frequent predictor.

PoPLAR: Portal for Petascale Lifescience Applications and Research

PubMed Central

2013-01-01

Background We are focusing specifically on fast data analysis and retrieval in bioinformatics that will have a direct impact on the quality of human health and the environment. The exponential growth of data generated in biology research, from small atoms to big ecosystems, necessitates an increasingly large computational component to perform analyses. Novel DNA sequencing technologies and complementary high-throughput approaches--such as proteomics, genomics, metabolomics, and meta-genomics--drive data-intensive bioinformatics. While individual research centers or universities could once provide for these applications, this is no longer the case. Today, only specialized national centers can deliver the level of computing resources required to meet the challenges posed by rapid data growth and the resulting computational demand. Consequently, we are developing massively parallel applications to analyze the growing flood of biological data and contribute to the rapid discovery of novel knowledge. Methods The efforts of previous National Science Foundation (NSF) projects provided for the generation of parallel modules for widely used bioinformatics applications on the Kraken supercomputer. We have profiled and optimized the code of some of the scientific community's most widely used desktop and small-cluster-based applications, including BLAST from the National Center for Biotechnology Information (NCBI), HMMER, and MUSCLE; scaled them to tens of thousands of cores on high-performance computing (HPC) architectures; made them robust and portable to next-generation architectures; and incorporated these parallel applications in science gateways with a web-based portal. Results This paper will discuss the various developmental stages, challenges, and solutions involved in taking bioinformatics applications from the desktop to petascale with a front-end portal for very-large-scale data analysis in the life sciences. Conclusions This research will help to bridge the gap between the rate of data generation and the speed at which scientists can study this data. The ability to rapidly analyze data at such a large scale is having a significant, direct impact on science achieved by collaborators who are currently using these tools on supercomputers. PMID:23902523

Precision measurement of the integrated luminosity of the data taken by BESIII at center-of-mass energies between 3.810 GeV and 4.600 GeV

NASA Astrophysics Data System (ADS)

Ablikim, M.; N. Achasov, M.; Ai, X. C.; Albayrak, O.; Albrecht, M.; J. Ambrose, D.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; R. Baldini, Ferroli; Ban, Y.; W. Bennett, D.; V. Bennett, J.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Bondarenko, O.; Boyko, I.; A. Briere, R.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; A. Cetin, S.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Cronin-Hennessy, D.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; F. De, Mori; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Fava, L.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, Y.; Gao, Z.; Garzia, I.; Geng, C.; Goetzen, K.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, Y.; P. Guo, Y.; Haddadi, Z.; Hafner, A.; Han, S.; Han, Y. L.; Hao, X. Q.; A. Harris, F.; He, K. L.; He, Z. Y.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. M.; Huang, G. S.; Huang, H. P.; Huang, J. S.; Huang, X. T.; Huang, Y.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. L.; Jiang, L. W.; Jiang, X. S.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; C. Ke, B.; Kliemt, R.; Kloss, B.; B. Kolcu, O.; Kopf, B.; Kornicer, M.; Kuehn, W.; Kupsc, A.; Lai, W.; S. Lange, J.; M., Lara; Larin, P.; Leng, C.; Li, C. H.; Li, Cheng; Li, D. M.; Li, F.; Li, G.; Li, H. B.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. M.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; X. Lin(Lin, D.; Liu, B. J.; Liu, C. X.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, X. X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqiang; Zhiqing, Liu; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, R. Q.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lv, M.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, Q. M.; Ma, S.; Ma, T.; Ma, X. N.; Ma, X. Y.; E. Maas, F.; Maggiora, M.; A. Malik, Q.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; G. Messchendorp, J.; Min, J.; Min, T. J.; E. Mitchell, R.; Mo, X. H.; Mo, Y. J.; C. Morales, Morales; Moriya, K.; Yu. Muchnoi, N.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; B. Nikolaev, I.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Ping, J. L.; Ping, R. G.; Poling, R.; Pu, Y. N.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Y.; Qin, Z. H.; Qiu, J. F.; H. Rashid, K.; F. Redmer, C.; Ren, H. L.; Ripka, M.; Rong, G.; Ruan, X. D.; Santoro, V.; Sarantsev, A.; Savrié, M.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; H. Thorndike, E.; Tiemens, M.; Toth, D.; Ullrich, M.; Uman, I.; S. Varner, G.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, Q. J.; Wang, S. G.; Wang, W.; Wang, X. F.; Yadi, Wang; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Wei, J. B.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. X.; Yang, L.; Yang, Y.; Yang, Y. X.; Ye, H.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, H. W.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; A. Zafar, A.; Zallo, A.; Zeng, Y.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. H.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, Li; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

2015-09-01

From December 2011 to May 2014, about 5 fb-1 of data were taken with the BESIII detector at center-of-mass energies between 3.810 GeV and 4.600 GeV to study the charmonium-like states and higher excited charmonium states. The time-integrated luminosity of the collected data sample is measured to a precision of 1% by analyzing events produced by the large-angle Bhabha scattering process. Supported by National Key Basic Research Program of China (2015CB856700), National Natural Science Foundation of China (NSFC) (11125525, 11235011, 11322544, 11335008, 11425524), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (11179007, U1232201, U1332201) CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey (DPT2006K-120470), Russian Foundation for Basic Research (14-07-91152), U.S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt and WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0)

The Center for Optimized Structural Studies (COSS) platform for automation in cloning, expression, and purification of single proteins and protein-protein complexes.

PubMed

Mlynek, Georg; Lehner, Anita; Neuhold, Jana; Leeb, Sarah; Kostan, Julius; Charnagalov, Alexej; Stolt-Bergner, Peggy; Djinović-Carugo, Kristina; Pinotsis, Nikos

2014-06-01

Expression in Escherichia coli represents the simplest and most cost effective means for the production of recombinant proteins. This is a routine task in structural biology and biochemistry where milligrams of the target protein are required in high purity and monodispersity. To achieve these criteria, the user often needs to screen several constructs in different expression and purification conditions in parallel. We describe a pipeline, implemented in the Center for Optimized Structural Studies, that enables the systematic screening of expression and purification conditions for recombinant proteins and relies on a series of logical decisions. We first use bioinformatics tools to design a series of protein fragments, which we clone in parallel, and subsequently screen in small scale for optimal expression and purification conditions. Based on a scoring system that assesses soluble expression, we then select the top ranking targets for large-scale purification. In the establishment of our pipeline, emphasis was put on streamlining the processes such that it can be easily but not necessarily automatized. In a typical run of about 2 weeks, we are able to prepare and perform small-scale expression screens for 20-100 different constructs followed by large-scale purification of at least 4-6 proteins. The major advantage of our approach is its flexibility, which allows for easy adoption, either partially or entirely, by any average hypothesis driven laboratory in a manual or robot-assisted manner.

Thermospheric Airglow Perturbations in the Upper Atmosphere Caused by Hurricane Harvey

NASA Astrophysics Data System (ADS)

Bhatt, A.; Kendall, E. A.

2017-12-01

The Midlatitude Allsky imaging Network for Geophysical Observations (MANGO) consists of seven allsky imagers distributed across the United States recording observations of large-scale airglow perturbations. The imagers are filtered at 630 nm, a forbidden oxygen line, in order to record the predominant source of airglow at 250 km altitude. While the ubiquitous airglow layer is challenging to observe when under uniform conditions, waves in the upper atmosphere cause ripples in the airglow layer which can easily be imaged by appropriate instrumentation. MANGO is the first network to record perturbations in the airglow layer on a continent-size scale. Large and Mid-scale Traveling Ionospheric Disturbances (LSTIDs and MSTIDs) are recorded that are caused by auroral forcing, mountain turbulence, and tidal variations. On August 25, airglow perturbations centered on the Hurricane Harvey path were observed by MANGO. These images and connections to other complimentary data sets such as GPS will be presented.

The Army’s National Training Center: A Case Study in Management of a Large Defense Project

DTIC Science & Technology

1983-04-26

34Desining . . .," op cit, p. 130. IT. M3l Ior-ritc’h and C. K. Prahalad , "Managing Multi-Organization Enterprises: The Emerging Strategic Frontier...Rational Altor TModel "assumes that what must be explained is an action, i.e., behavior that reflects purpose or intention .Ŗ It assumes "that what human...a fourth element is essential to the success of large-scale commerciali- zation programs: a favorable corporate strategic environment. This element

The dynamics underlying the regeneration and stalling of Hurricane Harvey

NASA Astrophysics Data System (ADS)

Liang, X. S.

2017-12-01

The explosive regeneration and stalling make the hurricane Harvey go from a little-noticed storm to an extremely destructive behemoth in late August 2017 that incurred an estimated economic loss at 70-200 billion USD. In this study, we use a recently developed analysis tool, namely, multiscale window transform (MWT), and the MWT-based theory of canonical transfer, to investigate the dynamics underlying this regeneration and stalling. The atmospheric fields are reconstructed onto three scale ranges or windows, namely, large-scale, tropical cyclone-scale, and cumulus convection-scale windows. The intertwined cyclone-scale nonlinear energy process is uniquely separated into a transport of energy within the cyclone window and an interscale transfer through reconstructing the "atomic" energy fluxes on the multiple scale windows. The resulting transfer bears a Lie bracket form, reminiscent of the Poisson bracket in Hamiltonian mechanics, and is hence referred to as canonical. It is found that within the Gulf of Mexico, Harvey gains much energy from the cumulus convection window through an inverse energy cascade, leading to its explosive growth. In the mean time, there is a barotropic instability (positive canonical transfer) center of the mean circulation in the lower and mid troposphere which lies quasi-steadily over Houston during August 22 through early September. The northwestward propagating Harvey meets that center and then stalls for two days near the coastline, dropping torrential and unprecedented amounts of rainfall and causing catastrophic flooding. It moves out of the instability center by the end of August, and then dissipates quickly in the following days.

Selection and Manufacturing of Membrane Materials for Solar Sails

NASA Technical Reports Server (NTRS)

Bryant, Robert G.; Seaman, Shane T.; Wilkie, W. Keats; Miyaucchi, Masahiko; Working, Dennis C.

2013-01-01

Commercial metallized polyimide or polyester films and hand-assembly techniques are acceptable for small solar sail technology demonstrations, although scaling this approach to large sail areas is impractical. Opportunities now exist to use new polymeric materials specifically designed for solar sailing applications, and take advantage of integrated sail manufacturing to enable large-scale solar sail construction. This approach has, in part, been demonstrated on the JAXA IKAROS solar sail demonstrator, and NASA Langley Research Center is now developing capabilities to produce ultrathin membranes for solar sails by integrating resin synthesis with film forming and sail manufacturing processes. This paper will discuss the selection and development of polymer material systems for space, and these new processes for producing ultrathin high-performance solar sail membrane films.

Large scale cryogenic fluid systems testing

NASA Technical Reports Server (NTRS)

1992-01-01

NASA Lewis Research Center's Cryogenic Fluid Systems Branch (CFSB) within the Space Propulsion Technology Division (SPTD) has the ultimate goal of enabling the long term storage and in-space fueling/resupply operations for spacecraft and reusable vehicles in support of space exploration. Using analytical modeling, ground based testing, and on-orbit experimentation, the CFSB is studying three primary categories of fluid technology: storage, supply, and transfer. The CFSB is also investigating fluid handling, advanced instrumentation, and tank structures and materials. Ground based testing of large-scale systems is done using liquid hydrogen as a test fluid at the Cryogenic Propellant Tank Facility (K-site) at Lewis' Plum Brook Station in Sandusky, Ohio. A general overview of tests involving liquid transfer, thermal control, pressure control, and pressurization is given.

Photogrammetry of a Hypersonic Inflatable Aerodynamic Decelerator

NASA Technical Reports Server (NTRS)

Kushner, Laura Kathryn; Littell, Justin D.; Cassell, Alan M.

2013-01-01

In 2012, two large-scale models of a Hypersonic Inflatable Aerodynamic decelerator were tested in the National Full-Scale Aerodynamic Complex at NASA Ames Research Center. One of the objectives of this test was to measure model deflections under aerodynamic loading that approximated expected flight conditions. The measurements were acquired using stereo photogrammetry. Four pairs of stereo cameras were mounted inside the NFAC test section, each imaging a particular section of the HIAD. The views were then stitched together post-test to create a surface deformation profile. The data from the photogram- metry system will largely be used for comparisons to and refinement of Fluid Structure Interaction models. This paper describes how a commercial photogrammetry system was adapted to make the measurements and presents some preliminary results.

Parallel Visualization of Large-Scale Aerodynamics Calculations: A Case Study on the Cray T3E

NASA Technical Reports Server (NTRS)

Ma, Kwan-Liu; Crockett, Thomas W.

1999-01-01

This paper reports the performance of a parallel volume rendering algorithm for visualizing a large-scale, unstructured-grid dataset produced by a three-dimensional aerodynamics simulation. This dataset, containing over 18 million tetrahedra, allows us to extend our performance results to a problem which is more than 30 times larger than the one we examined previously. This high resolution dataset also allows us to see fine, three-dimensional features in the flow field. All our tests were performed on the Silicon Graphics Inc. (SGI)/Cray T3E operated by NASA's Goddard Space Flight Center. Using 511 processors, a rendering rate of almost 9 million tetrahedra/second was achieved with a parallel overhead of 26%.

Direct and inverse energy cascades in a forced rotating turbulence experiment

NASA Astrophysics Data System (ADS)

Campagne, Antoine; Gallet, Basile; Moisy, Frédéric; Cortet, Pierre-Philippe

2014-11-01

Turbulence in a rotating frame provides a remarkable system where 2D and 3D properties may coexist, with a possible tuning between direct and inverse cascades. We present here experimental evidence for a double cascade of kinetic energy in a statistically stationary rotating turbulence experiment. Turbulence is generated by a set of vertical flaps which continuously injects velocity fluctuations towards the center of a rotating water tank. The energy transfers are evaluated from two-point third-order three-component velocity structure functions, which we measure using stereoscopic PIV in the rotating frame. Without global rotation, the energy is transferred from large to small scales, as in classical 3D turbulence. For nonzero rotation rates, the horizontal kinetic energy presents a double cascade: a direct cascade at small horizontal scales and an inverse cascade at large horizontal scales. By contrast, the vertical kinetic energy is always transferred from large to small horizontal scales, a behavior reminiscent of the dynamics of a passive scalar in 2D turbulence. At the largest rotation rate, the flow is nearly 2D and a pure inverse energy cascade is found for the horizontal energy.

HCN(1-0) enhancement in the bar of NGC 2903

NASA Astrophysics Data System (ADS)

Leon, S.; Jeyakumar, S.; Pérez-Ramírez, D.; Verdes-Montenegro, L.; Lee, S. W.; Ocaña Flaquer, B.

2008-12-01

We have mapped the HCN(1-0) emission from two spiral galaxies, NGC 2903 and NGC 3504 to study the gas properties in the bars. The HCN(1-0) emission is detected in the center and along the bar of NGC 2903. The line ratio HCN(1-0)/ 12CO(1-0) ranges from 0.07 to 0.12 with the lowest value in the center. The enhancement of HCN(1-0) emission along the bar indicates a higher fraction of dense molecular gas in the bar than at the center. The mass of dense molecular gas in the center (2.2 × 107 M⊙) is about 6 times lower than that in the bar (1.2 × 108 M⊙). The total star formation rate (SFR) is estimated to be 1.4 M⊙ yr-1, where the SFR at the center is 1.9 times higher than that in the bar. The time scale of consumption of the dense molecular gas in the center is about ~ 3 × 107 yr which is much shorter than that in the bar of about 2 to 10 × 108 yr. The dynamical time scale of inflow of the gas from the bar to the center is shorter than the consumption time scale in the bar, which suggests that the star formation (SF) activity at the center is not deprived of fuel. In the bar, the fraction of dense molecular gas mass relative to the total molecular gas mass is twice as high along the leading edge than along the central axis of the bar. The HCN(1-0) emission has a large velocity dispersion in the bar, which can be attributed partially to the streaming motions indicative of shocks along the bar. In NGC 3504, the HCN(1-0) emission is detected only at the center. The fraction of dense molecular gas mass in the center is about 15%. Comparison of the SFR with the predictions from numerical simulations suggest that NGC 2903 harbors a young type B bar with a strong inflow of gas toward the center whereas NGC 3504 has an older bar and has already passed the phase of inflow of gas toward the center.

AirSTAR: A UAV Platform for Flight Dynamics and Control System Testing

NASA Technical Reports Server (NTRS)

Jordan, Thomas L.; Foster, John V.; Bailey, Roger M.; Belcastro, Christine M.

2006-01-01

As part of the NASA Aviation Safety Program at Langley Research Center, a dynamically scaled unmanned aerial vehicle (UAV) and associated ground based control system are being developed to investigate dynamics modeling and control of large transport vehicles in upset conditions. The UAV is a 5.5% (seven foot wingspan), twin turbine, generic transport aircraft with a sophisticated instrumentation and telemetry package. A ground based, real-time control system is located inside an operations vehicle for the research pilot and associated support personnel. The telemetry system supports over 70 channels of data plus video for the downlink and 30 channels for the control uplink. Data rates are in excess of 200 Hz. Dynamic scaling of the UAV, which includes dimensional, weight, inertial, actuation, and control system scaling, is required so that the sub-scale vehicle will realistically simulate the flight characteristics of the full-scale aircraft. This testbed will be utilized to validate modeling methods, flight dynamics characteristics, and control system designs for large transport aircraft, with the end goal being the development of technologies to reduce the fatal accident rate due to loss-of-control.

Modeled change in carbon balance between 1970-2100 of a polygonal arctic tundra ecosystem near Barrow, Alaska

NASA Astrophysics Data System (ADS)

Lara, M. J.; McGuire, A. D.; Euskirchen, E. S.; Sloan, V. L.; Iversen, C. M.; Norby, R. J.; Genet, H.; Zhang, Y.; Yuan, F.

2013-12-01

Northern permafrost regions are estimated to cover 16% of the global soil area and account for approximately 50% of the global belowground organic carbon pool. However, there are considerable uncertainties regarding the fate of this soil carbon pool with projected climate warming over the next century. In northern Alaska, nearly 65% of the terrestrial surface is composed of polygonal tundra, where microtopographic position (i.e. high center, low center, trough) varies surface hydrology, plant community composition, and biogeochemical cycling, over small (<5m) spatial scales. Due to large spatial heterogeneity and other non-linear responses of soil carbon to altered thermal regime, it is difficult to accurately estimate the fate of terrestrial carbon balance over decadal time-scales without explicitly considering the dynamically coupled processes driving permafrost dynamics, community structure, and ecosystem function. We use a new version of the terrestrial ecosystem model (TEM), which couples a dynamic vegetation and dynamic organic soil model (DVM-DOS-TEM). This large-scale ecosystem model is designed to study interactions among carbon and nitrogen cycling, vegetation composition, and soil physical properties, including permafrost and active layer dynamics. The model is parameterized and calibrated using data specific to the local climate, vegetation, and soils within various polygon land cover types (i.e. high center & rim, low center, trough) collected from sites (71.28°N 156.60° W) on the arctic coastal plain near Barrow, Alaska to estimate the likely change in carbon balance between 1970 and 2100 in this landscape. Model outputs are scaled across the Barrow Peninsula using the distribution of polygonal tundra land cover types, described by a land cover classification of 26.9 km2, using a 2008 multi-spectral QuickBird satellite image. The polygonal tundra land cover classification found high center & rims to represent 37.5% of the study area, low centers 19.7%, troughs 9.9%, water bodies (i.e. lakes, ponds, rivers) 17.8%, and non-polygonal tundra (i.e. drainage terraces & graminoid meadows) 15.1%, respectively. The overall accuracy of the map was 86%, based on 250 ground control points, and the Kappa coefficient was 0.77. Preliminary model runs for this region indicated variability in response to specific polygonal tundra land cover type through time. Overall, results suggest that it is important to consider discrete polygonal tundra features in regional estimates of carbon balance in northern Alaska.

Examination of Daily Weather in the NCAR CCM

NASA Astrophysics Data System (ADS)

Cocke, S. D.

2006-05-01

The NCAR CCM is one of the most extensively studied climate models in the scientific community. However, most studies focus primarily on the long term mean behavior, typically monthly or longer time scales. In this study we examine the daily weather in the GCM by performing a series of daily or weekly 10 day forecasts for one year at moderate (T63) and high (T126) resolution. The model is initialized with operational "AVN" and ECMWF analyses, and model performance is compared to that of major operational centers, using conventional skill scores used by the major centers. Such a detailed look at the CCM at shorter time scales may lead to improvements in physical parameterizations, which may in turn lead to improved climate simulations. One finding from this study is that the CCM has a significant drying tendency in the lower troposphere compared to the operational analyses. Another is that the large scale predictability of the GCM is competitive with most of the operational models, particularly in the southern hemisphere.

Vanderbilt University Institute of Imaging Science Center for Computational Imaging XNAT: A multimodal data archive and processing environment.

PubMed

Harrigan, Robert L; Yvernault, Benjamin C; Boyd, Brian D; Damon, Stephen M; Gibney, Kyla David; Conrad, Benjamin N; Phillips, Nicholas S; Rogers, Baxter P; Gao, Yurui; Landman, Bennett A

2016-01-01

The Vanderbilt University Institute for Imaging Science (VUIIS) Center for Computational Imaging (CCI) has developed a database built on XNAT housing over a quarter of a million scans. The database provides framework for (1) rapid prototyping, (2) large scale batch processing of images and (3) scalable project management. The system uses the web-based interfaces of XNAT and REDCap to allow for graphical interaction. A python middleware layer, the Distributed Automation for XNAT (DAX) package, distributes computation across the Vanderbilt Advanced Computing Center for Research and Education high performance computing center. All software are made available in open source for use in combining portable batch scripting (PBS) grids and XNAT servers. Copyright © 2015 Elsevier Inc. All rights reserved.

The SCALE-UP Project

NASA Astrophysics Data System (ADS)

Beichner, Robert

2015-03-01

The Student Centered Active Learning Environment with Upside-down Pedagogies (SCALE-UP) project was developed nearly 20 years ago as an economical way to provide collaborative, interactive instruction even for large enrollment classes. Nearly all research-based pedagogies have been designed with fairly high faculty-student ratios. The economics of introductory courses at large universities often precludes that situation, so SCALE-UP was created as a way to facilitate highly collaborative active learning with large numbers of students served by only a few faculty and assistants. It enables those students to learn and succeed not only in acquiring content, but also to practice important 21st century skills like problem solving, communication, and teamsmanship. The approach was initially targeted at undergraduate science and engineering students taking introductory physics courses in large enrollment sections. It has since expanded to multiple content areas, including chemistry, math, engineering, biology, business, nursing, and even the humanities. Class sizes range from 24 to over 600. Data collected from multiple sites around the world indicates highly successful implementation at more than 250 institutions. NSF support was critical for initial development and dissemination efforts. Generously supported by NSF (9752313, 9981107) and FIPSE (P116B971905, P116B000659).

An Overview of NASA's In-Space Cryogenic Propellant Management Technologies

NASA Technical Reports Server (NTRS)

Tucker, Stephen; Hastings, Leon; Haynes, Davy (Technical Monitor)

2001-01-01

Future mission planning within NASA continues to include cryogenic propellants for in space transportation, with mission durations ranging from days to years. Between 1995 and the present, NASA has pursued a diversified program of ground-based testing to prepare the various technologies associated with in-space cryogenic fluid management (CFM) for implementation. CFM technology areas being addressed include passive insulation, zero gravity pressure control, zero gravity mass gauging, capillary liquid acquisition devices, and zero boiloff storage. NASA CFM technologies are planned, coordinated, and implemented through the Cryogenic Technology Working Group which is comprised of representatives from the various NASA Centers as well as the National Institute of Standards and Technologies (NIST) and, on selected occasions, the Air Force. An overview of the NASA program and Marshall Space Flight Center (MSFC) roles, accomplishments, and near-term activities are presented herein. Basic CFM technology areas being addressed include passive insulation, zero gravity pressure control, zero gravity mass gauging, capillary liquid acquisition devices, and zero boiloff storage. Recent MSFC accomplishments include: the large scale demonstration of a high performance variable density multilayer insulation (MLI) that reduced the boiloff by about half that of standard MLI; utilization of a foam substrate under MLI to eliminate the need for a helium purge bag system; demonstrations of both spray-bar and axial-jet mixer concepts for zero gravity pressure control; and sub-scale testing that verified an optical sensor concept for measuring liquid hydrogen mass in zero gravity. In response to missions requiring cryogenic propellant storage durations on the order of years, a cooperative effort by NASA's Ames Research Center, Glenn Research Center, and MSFC has been implemented to develop and demonstrate zero boiloff concepts for in-space storage of cryogenic propellants. An MSFC contribution to this cooperative effort is a large-scale demonstration of the integrated operation of passive insulation, destratification/pressure control, and cryocooler (commercial unit) subsystems to achieve zero boiloff storage of liquid hydrogen. Testing is expected during the Summer of 2001.

A Hybrid Coarse-graining Approach for Lipid Bilayers at Large Length and Time Scales

PubMed Central

Ayton, Gary S.; Voth, Gregory A.

2009-01-01

A hybrid analytic-systematic (HAS) coarse-grained (CG) lipid model is developed and employed in a large-scale simulation of a liposome. The methodology is termed hybrid analyticsystematic as one component of the interaction between CG sites is variationally determined from the multiscale coarse-graining (MS-CG) methodology, while the remaining component utilizes an analytic potential. The systematic component models the in-plane center of mass interaction of the lipids as determined from an atomistic-level MD simulation of a bilayer. The analytic component is based on the well known Gay-Berne ellipsoid of revolution liquid crystal model, and is designed to model the highly anisotropic interactions at a highly coarse-grained level. The HAS CG approach is the first step in an “aggressive” CG methodology designed to model multi-component biological membranes at very large length and timescales. PMID:19281167

Bureaucratic Activism and Radical School Change in Tamil Nadu, India

ERIC Educational Resources Information Center

Niesz, Tricia; Krishnamurthy, Ramchandar

2013-01-01

In 2007, Activity Based Learning (ABL), a child-centered, activity-based method of pedagogical practice, transformed classrooms in all of the over 37,000 primary-level government schools in Tamil Nadu, India. The large scale, rapid pace, and radical nature of educational change sets the ABL initiative apart from most school reform efforts.…

Effects of a Data-Driven District-Level Reform Model

ERIC Educational Resources Information Center

Slavin, Robert E.; Holmes, GwenCarol; Madden, Nancy A.; Chamberlain, Anne; Cheung, Alan

2010-01-01

Despite a quarter-century of reform, US schools serving students in poverty continue to lag far behind other schools. There are proven programs, but these are not widely used. This large-scale experiment evaluated a district-level reform model created by the Center for DataDriven Reform in Education (CDDRE). The CDDRE model provided consultation…

Technical Assessment: Integrated Photonics

DTIC Science & Technology

2015-10-01

in global internet protocol traffic as a function of time by local access technology. Photonics continues to play a critical role in enabling this...communication networks. This has enabled services like the internet , high performance computing, and power-efficient large-scale data centers. The...signal processing, quantum information science, and optics for free space applications. However major obstacles challenge the implementation of

Beyond the Classroom: Creating and Implementing New Models for Teaching.

ERIC Educational Resources Information Center

Free, Coen; Moerman, Yvonne

In the Netherlands, educational innovation related to community colleges has mostly emphasized enlarging the scale of the colleges, resulting in large regional educational centers serving 10,000 students or more. New demand on the educational process has also resulted in a growing examination of the role of the teacher in the classroom. At King…

Wildland fire probabilities estimated from weather model-deduced monthly mean fire danger indices

Treesearch

Haiganoush K. Preisler; Shyh-Chin Chen; Francis Fujioka; John W. Benoit; Anthony L. Westerling

2008-01-01

The National Fire Danger Rating System indices deduced from a regional simulation weather model were used to estimate probabilities and numbers of large fire events on monthly and 1-degree grid scales. The weather model simulations and forecasts are ongoing experimental products from the Experimental Climate Prediction Center at the Scripps Institution of Oceanography...

XC-142 Tilt Wing; 0.6 Scale Model in the 40x80 Foot Wind Tunnel at NASA Ames Research Center.

NASA Image and Video Library

1964-01-22

3/4 front right side only with Tim Wills on right and Charles Greco, mechanic. Large flaps on Variable height struts. XC-142 was a tri-service tiltwing experimental aircraft designed to investigate the operational suitability of vertical/short takeoff and landing (V/STOL) transports.

International Comparative Studies in Education: Descriptions of Selected Large-Scale Assessments and Case Studies.

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC. Commission on Behavioral and Social Sciences and Education.

Since its inception in 1988, the Board on International Comparative Studies in Education (BICSE) has monitored U.S. participation in those cross national comparative studies in education that are funded by its sponsors, the National Science Foundation and the National Center for Education Statistics. This set of international study descriptions…

The Promises and Challenges of Implementing Evidence-Centered Design in Large Scale Assessment

ERIC Educational Resources Information Center

Huff, Kristen; Steinberg, Linda; Matts, Tom

2009-01-01

Presented at the Annual Meeting of National Council on Measurement in Education (NCME) in San Diego, CA in April 2009. This presentation provides an overview of ECD. In addition, the presentation describes the benefits of, as well as the challenges that were faced, in implementing ECD in the Advanced Placement Program.

Pre-Layoff Intervention: A Response to Unemployment. Second Edition.

ERIC Educational Resources Information Center

Stone, Judson; And Others

Based on a program provided by a consortium of mental health centers in the Detroit, Michigan, area, this manual is intended to assist in the development and delivery of programs that allay or prevent the devastating human impact of plant shutdowns and large-scale layoffs. The guide focuses on delivery of programs that promote more effective use…

An Evaluation of the Conditions, Processes, and Consequences of Laptop Computing in K-12 Classrooms

ERIC Educational Resources Information Center

Cavanaugh, Cathy; Dawson, Kara; Ritzhaupt, Albert

2011-01-01

This article examines how laptop computing technology, teacher professional development, and systematic support resulted in changed teaching practices and increased student achievement in 47 K-12 schools in 11 Florida school districts. The overview of a large-scale study documents the type and magnitude of change in student-centered teaching,…

ET4ET: A Large-Scale Faculty Professional Development Program on Effective Integration of Educational Technology

ERIC Educational Resources Information Center

Murthy, Sahana; Iyer, Sridhar; Warriem, Jayakrishnan

2015-01-01

Educators have recommended that the affordances provided by ICTs should be used to promote student-centered constructivist learning. While the actual use of ICT in education has increased, not much change has occurred in terms of the pedagogical practices followed. Information transmission models of teaching are still being followed, albeit with…

The Labor Market Returns to Sub-Baccalaureate College: A Review. A CAPSEE Working Paper

ERIC Educational Resources Information Center

Belfield, Clive; Bailey, Thomas

2017-01-01

This paper reviews recent evidence on the labor market returns to credit accumulation, certificates, and associate degrees from community colleges. Evidence is collated from estimates of earnings gaps across college students using large-scale, statewide administrative datasets from eight states. Six of these states were partners of the Center for…

Adsorption and diffusion of Ru adatoms on Ru(0001)-supported graphene: Large-scale first-principles calculations

DOE PAGES

Han, Yong; Evans, James W.

2015-10-27

Large-scale first-principles density functional theory calculations are performed to investigate the adsorption and diffusion of Ru adatoms on monolayer graphene (G) supported on Ru(0001). The G sheet exhibits a periodic moiré-cell superstructure due to lattice mismatch. Within a moiré cell, there are three distinct regions: fcc, hcp, and mound, in which the C6-ring center is above a fcc site, a hcp site, and a surface Ru atom of Ru(0001), respectively. The adsorption energy of a Ru adatom is evaluated at specific sites in these distinct regions. We find the strongest binding at an adsorption site above a C atom inmore » the fcc region, next strongest in the hcp region, then the fcc-hcp boundary (ridge) between these regions, and the weakest binding in the mound region. Behavior is similar to that observed from small-unit-cell calculations of Habenicht et al. [Top. Catal. 57, 69 (2014)], which differ from previous large-scale calculations. We determine the minimum-energy path for local diffusion near the center of the fcc region and obtain a local diffusion barrier of ~0.48 eV. We also estimate a significantly lower local diffusion barrier in the ridge region. These barriers and information on the adsorption energy variation facilitate development of a realistic model for the global potential energy surface for Ru adatoms. Furthermore, this in turn enables simulation studies elucidating diffusion-mediated directed-assembly of Ru nanoclusters during deposition of Ru on G/Ru(0001).« less

Long-term change of potential evapotranspiration over Southwest China and teleconnections with large-scale climate anomalies

NASA Astrophysics Data System (ADS)

Liu, B.; Chen, X.; Li, Y.; Chen, Z.

2017-12-01

bstract: Potential evapotranspiration (PET) is a sensitive factor for atmospheric and ecological systems over Southwest China which is characterized by intensive karst geomorphology and fragile environment. Based on daily meteorological data of 94 stations during 1961-2013, the spatiotemporal characteristics of PET are analyzed. The changing characteristics of local meteorological factors and large-scale climatic features are also investigated to explain the potential reasons for changing PET. Study results are as follows: (1) The high-value center of PET with a mean value of 1097 mm/a locates in the south mainly resulted from the regional climatic features of higher air temperature (TEM), sunshine duration (SSD) and lower relative humidity (RHU); and the low-value center of PET with a mean value of 831 mm/a is in the northeast primarily attributed to higher RHU and weaker SSD. (2) Annual PET decreases at -10.04 mm decade-1 before the year 2000 but increases at 50.65 mm decade-1 thereafter; and the dominant factors of PET change are SSD, RHU and wind speed (WIN), with the relative contributions of 33.29%, 25.42% and 22.16%, respectively. (3) The abrupt change of PET in 2000 is strongly dominated by large-scale climatic anomalies. The strengthened 850hPa geostrophic wind (0.51 ms-1 decade-1), weakened total cloud cover (-2.25 % decade-1) and 500hPa water vapor flux (-2.85 % decade-1) have provided advantageous dynamic, thermal and dry conditions for PET over Southwest China since the 21st century.

Adsorption and diffusion of Ru adatoms on Ru(0001)-supported graphene: Large-scale first-principles calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, Yong; Evans, James W.

2015-10-28

Large-scale first-principles density functional theory calculations are performed to investigate the adsorption and diffusion of Ru adatoms on monolayer graphene (G) supported on Ru(0001). The G sheet exhibits a periodic moiré-cell superstructure due to lattice mismatch. Within a moiré cell, there are three distinct regions: fcc, hcp, and mound, in which the C{sub 6}-ring center is above a fcc site, a hcp site, and a surface Ru atom of Ru(0001), respectively. The adsorption energy of a Ru adatom is evaluated at specific sites in these distinct regions. We find the strongest binding at an adsorption site above a C atommore » in the fcc region, next strongest in the hcp region, then the fcc-hcp boundary (ridge) between these regions, and the weakest binding in the mound region. Behavior is similar to that observed from small-unit-cell calculations of Habenicht et al. [Top. Catal. 57, 69 (2014)], which differ from previous large-scale calculations. We determine the minimum-energy path for local diffusion near the center of the fcc region and obtain a local diffusion barrier of ∼0.48 eV. We also estimate a significantly lower local diffusion barrier in the ridge region. These barriers and information on the adsorption energy variation facilitate development of a realistic model for the global potential energy surface for Ru adatoms. This in turn enables simulation studies elucidating diffusion-mediated directed-assembly of Ru nanoclusters during deposition of Ru on G/Ru(0001)« less

Development of a database system for mapping insertional mutations onto the mouse genome with large-scale experimental data

PubMed Central

2009-01-01

Background Insertional mutagenesis is an effective method for functional genomic studies in various organisms. It can rapidly generate easily tractable mutations. A large-scale insertional mutagenesis with the piggyBac (PB) transposon is currently performed in mice at the Institute of Developmental Biology and Molecular Medicine (IDM), Fudan University in Shanghai, China. This project is carried out via collaborations among multiple groups overseeing interconnected experimental steps and generates a large volume of experimental data continuously. Therefore, the project calls for an efficient database system for recording, management, statistical analysis, and information exchange. Results This paper presents a database application called MP-PBmice (insertional mutation mapping system of PB Mutagenesis Information Center), which is developed to serve the on-going large-scale PB insertional mutagenesis project. A lightweight enterprise-level development framework Struts-Spring-Hibernate is used here to ensure constructive and flexible support to the application. The MP-PBmice database system has three major features: strict access-control, efficient workflow control, and good expandability. It supports the collaboration among different groups that enter data and exchange information on daily basis, and is capable of providing real time progress reports for the whole project. MP-PBmice can be easily adapted for other large-scale insertional mutation mapping projects and the source code of this software is freely available at http://www.idmshanghai.cn/PBmice. Conclusion MP-PBmice is a web-based application for large-scale insertional mutation mapping onto the mouse genome, implemented with the widely used framework Struts-Spring-Hibernate. This system is already in use by the on-going genome-wide PB insertional mutation mapping project at IDM, Fudan University. PMID:19958505

Effects of Large-Scale Solar Installations on Dust Mobilization and Air Quality

NASA Astrophysics Data System (ADS)

Pratt, J. T.; Singh, D.; Diffenbaugh, N. S.

2012-12-01

Large-scale solar projects are increasingly being developed worldwide and many of these installations are located in arid, desert regions. To examine the effects of these projects on regional dust mobilization and air quality, we analyze aerosol product data from NASA's Multi-angle Imaging Spectroradiometer (MISR) at annual and seasonal time intervals near fifteen photovoltaic and solar thermal stations ranging from 5-200 MW (12-4,942 acres) in size. The stations are distributed over eight different countries and were chosen based on size, location and installation date; most of the installations are large-scale, took place in desert climates and were installed between 2006 and 2010. We also consider air quality measurements of particulate matter between 2.5 and 10 micrometers (PM10) from the Environmental Protection Agency (EPA) monitoring sites near and downwind from the project installations in the U.S. We use monthly wind data from the NOAA's National Center for Atmospheric Prediction (NCEP) Global Reanalysis to select the stations downwind from the installations, and then perform statistical analysis on the data to identify any significant changes in these quantities. We find that fourteen of the fifteen regions have lower aerosol product after the start of the installations as well as all six PM10 monitoring stations showing lower particulate matter measurements after construction commenced. Results fail to show any statistically significant differences in aerosol optical index or PM10 measurements before and after the large-scale solar installations. However, many of the large installations are very recent, and there is insufficient data to fully understand the long-term effects on air quality. More data and higher resolution analysis is necessary to better understand the relationship between large-scale solar, dust and air quality.

The MMPI-2 Symptom Validity Scale (FBS) not influenced by medical impairment: a large sleep center investigation.

PubMed

Greiffenstein, Manfred F

2010-06-01

The Symptom Validity Scale (Minnesota Multiphasic Personality Inventory-2-FBS [MMPI-2-FBS]) is a standard MMPI-2 validity scale measuring overstatement of somatic distress and subjective disability. Some critics assert the MMPI-2-FBS misclassifies too many medically impaired persons as malingering symptoms. This study tests the assertion of malingering misclassification with a large sample of 345 medical inpatients undergoing sleep studies that standardly included MMPI-2 testing. The variables included standard MMPI-2 validity scales (Lie Scale [L], Infrequency Scale [F], K-Correction [K]; FBS), objective medical data (e.g., body mass index, pulse oximetry), and polysomnographic scores (e.g., apnea/hypopnea index). The results showed the FBS had no substantial or unique association with medical/sleep variables, produced false positive rates <20% (median = 9, range = 4-11), and male inpatients showed marginally higher failure rates than females. The MMPI-2-FBS appears to have acceptable specificity, because it did not misclassify as biased responders those medical patients with sleep problems, male or female, with primary gain only (reducing sickness). Medical impairment does not appear to be a major influence on deviant MMPI-2-FBS scores.

Dynamic structural disorder in supported nanoscale catalysts

NASA Astrophysics Data System (ADS)

Rehr, J. J.; Vila, F. D.

2014-04-01

We investigate the origin and physical effects of "dynamic structural disorder" (DSD) in supported nano-scale catalysts. DSD refers to the intrinsic fluctuating, inhomogeneous structure of such nano-scale systems. In contrast to bulk materials, nano-scale systems exhibit substantial fluctuations in structure, charge, temperature, and other quantities, as well as large surface effects. The DSD is driven largely by the stochastic librational motion of the center of mass and fluxional bonding at the nanoparticle surface due to thermal coupling with the substrate. Our approach for calculating and understanding DSD is based on a combination of real-time density functional theory/molecular dynamics simulations, transient coupled-oscillator models, and statistical mechanics. This approach treats thermal and dynamic effects over multiple time-scales, and includes bond-stretching and -bending vibrations, and transient tethering to the substrate at longer ps time-scales. Potential effects on the catalytic properties of these clusters are briefly explored. Model calculations of molecule-cluster interactions and molecular dissociation reaction paths are presented in which the reactant molecules are adsorbed on the surface of dynamically sampled clusters. This model suggests that DSD can affect both the prefactors and distribution of energy barriers in reaction rates, and thus can significantly affect catalytic activity at the nano-scale.

Sign: large-scale gene network estimation environment for high performance computing.

PubMed

Tamada, Yoshinori; Shimamura, Teppei; Yamaguchi, Rui; Imoto, Seiya; Nagasaki, Masao; Miyano, Satoru

2011-01-01

Our research group is currently developing software for estimating large-scale gene networks from gene expression data. The software, called SiGN, is specifically designed for the Japanese flagship supercomputer "K computer" which is planned to achieve 10 petaflops in 2012, and other high performance computing environments including Human Genome Center (HGC) supercomputer system. SiGN is a collection of gene network estimation software with three different sub-programs: SiGN-BN, SiGN-SSM and SiGN-L1. In these three programs, five different models are available: static and dynamic nonparametric Bayesian networks, state space models, graphical Gaussian models, and vector autoregressive models. All these models require a huge amount of computational resources for estimating large-scale gene networks and therefore are designed to be able to exploit the speed of 10 petaflops. The software will be available freely for "K computer" and HGC supercomputer system users. The estimated networks can be viewed and analyzed by Cell Illustrator Online and SBiP (Systems Biology integrative Pipeline). The software project web site is available at http://sign.hgc.jp/ .

Opportunities for Breakthroughs in Large-Scale Computational Simulation and Design

NASA Technical Reports Server (NTRS)

Alexandrov, Natalia; Alter, Stephen J.; Atkins, Harold L.; Bey, Kim S.; Bibb, Karen L.; Biedron, Robert T.; Carpenter, Mark H.; Cheatwood, F. McNeil; Drummond, Philip J.; Gnoffo, Peter A.

2002-01-01

Opportunities for breakthroughs in the large-scale computational simulation and design of aerospace vehicles are presented. Computational fluid dynamics tools to be used within multidisciplinary analysis and design methods are emphasized. The opportunities stem from speedups and robustness improvements in the underlying unit operations associated with simulation (geometry modeling, grid generation, physical modeling, analysis, etc.). Further, an improved programming environment can synergistically integrate these unit operations to leverage the gains. The speedups result from reducing the problem setup time through geometry modeling and grid generation operations, and reducing the solution time through the operation counts associated with solving the discretized equations to a sufficient accuracy. The opportunities are addressed only at a general level here, but an extensive list of references containing further details is included. The opportunities discussed are being addressed through the Fast Adaptive Aerospace Tools (FAAST) element of the Advanced Systems Concept to Test (ASCoT) and the third Generation Reusable Launch Vehicles (RLV) projects at NASA Langley Research Center. The overall goal is to enable greater inroads into the design process with large-scale simulations.

A Ground-Based Research Vehicle for Base Drag Studies at Subsonic Speeds

NASA Technical Reports Server (NTRS)

Diebler, Corey; Smith, Mark

2002-01-01

A ground research vehicle (GRV) has been developed to study the base drag on large-scale vehicles at subsonic speeds. Existing models suggest that base drag is dependent upon vehicle forebody drag, and for certain configurations, the total drag of a vehicle can be reduced by increasing its forebody drag. Although these models work well for small projectile shapes, studies have shown that they do not provide accurate predictions when applied to large-scale vehicles. Experiments are underway at the NASA Dryden Flight Research Center to collect data at Reynolds numbers to a maximum of 3 x 10(exp 7), and to formulate a new model for predicting the base drag of trucks, buses, motor homes, reentry vehicles, and other large-scale vehicles. Preliminary tests have shown errors as great as 70 percent compared to Hoerner's two-dimensional base drag prediction. This report describes the GRV and its capabilities, details the studies currently underway at NASA Dryden, and presents preliminary results of both the effort to formulate a new base drag model and the investigation into a method of reducing total drag by manipulating forebody drag.

Enterprise PACS and image distribution.

PubMed

Huang, H K

2003-01-01

Around the world now, because of the need to improve operation efficiency and better cost effective healthcare, many large-scale healthcare enterprises have been formed. Each of these enterprises groups hospitals, medical centers, and clinics together as one enterprise healthcare network. The management of these enterprises recognizes the importance of using PACS and image distribution as a key technology in cost-effective healthcare delivery in the enterprise level. As a result, many large-scale enterprise level PACS/image distribution pilot studies, full design and implementation, are underway. The purpose of this paper is to provide readers an overall view of the current status of enterprise PACS and image distribution. reviews three large-scale enterprise PACS/image distribution systems in USA, Germany, and South Korean. The concept of enterprise level PACS/image distribution, its characteristics and ingredients are then discussed. Business models for enterprise level implementation available by the private medical imaging and system integration industry are highlighted. One current system under development in designing a healthcare enterprise level chest tuberculosis (TB) screening in Hong Kong is described in detail. Copyright 2002 Elsevier Science Ltd.

GSDC: A Unique Data Center in Korea for HEP research

NASA Astrophysics Data System (ADS)

Ahn, Sang-Un

2017-04-01

Global Science experimental Data hub Center (GSDC) at Korea Institute of Science and Technology Information (KISTI) is a unique data center in South Korea established for promoting the fundamental research fields by supporting them with the expertise on Information and Communication Technology (ICT) and the infrastructure for High Performance Computing (HPC), High Throughput Computing (HTC) and Networking. GSDC has supported various research fields in South Korea dealing with the large scale of data, e.g. RENO experiment for neutrino research, LIGO experiment for gravitational wave detection, Genome sequencing project for bio-medical, and HEP experiments such as CDF at FNAL, Belle at KEK, and STAR at BNL. In particular, GSDC has run a Tier-1 center for ALICE experiment using the LHC at CERN since 2013. In this talk, we present the overview on computing infrastructure that GSDC runs for the research fields and we discuss on the data center infrastructure management system deployed at GSDC.

Optimal distribution of medical backpacks and health surveillance assistants in Malawi.

PubMed

Kunkel, Amber G; Van Itallie, Elizabeth S; Wu, Duo

2014-09-01

Despite recent progress, Malawi continues to perform poorly on key health indicators such as child mortality and life expectancy. These problems are exacerbated by a severe lack of access to health care. Health Surveillance Assistants (HSAs) help bridge this gap by providing community-level access to basic health care services. However, the success of these HSAs is limited by a lack of supplies and long distances between HSAs and patients. To address this issue, we used large-scale weighted p-median and capacitated facility location problems to create a scalable, three-tiered plan for optimal allocation of HSAs, HSA designated medical backpacks, and backpack resupply centers. Our analysis uses real data on the location and characteristics of hospitals, health centers, and the general population. In addition to offering specific recommendations for HSA, backpack, and resupply center locations, it provides general insights into the scope of the proposed HSA backpack program scale-up. In particular, it demonstrates the importance of local health centers to the resupply network. The proposed assignments are robust to changes in the underlying population structure, and could significantly improve access to medical supplies for both HSAs and patients.

The Transgenic RNAi Project at Harvard Medical School: Resources and Validation.

PubMed

Perkins, Lizabeth A; Holderbaum, Laura; Tao, Rong; Hu, Yanhui; Sopko, Richelle; McCall, Kim; Yang-Zhou, Donghui; Flockhart, Ian; Binari, Richard; Shim, Hye-Seok; Miller, Audrey; Housden, Amy; Foos, Marianna; Randkelv, Sakara; Kelley, Colleen; Namgyal, Pema; Villalta, Christians; Liu, Lu-Ping; Jiang, Xia; Huan-Huan, Qiao; Wang, Xia; Fujiyama, Asao; Toyoda, Atsushi; Ayers, Kathleen; Blum, Allison; Czech, Benjamin; Neumuller, Ralph; Yan, Dong; Cavallaro, Amanda; Hibbard, Karen; Hall, Don; Cooley, Lynn; Hannon, Gregory J; Lehmann, Ruth; Parks, Annette; Mohr, Stephanie E; Ueda, Ryu; Kondo, Shu; Ni, Jian-Quan; Perrimon, Norbert

2015-11-01

To facilitate large-scale functional studies in Drosophila, the Drosophila Transgenic RNAi Project (TRiP) at Harvard Medical School (HMS) was established along with several goals: developing efficient vectors for RNAi that work in all tissues, generating a genome-scale collection of RNAi stocks with input from the community, distributing the lines as they are generated through existing stock centers, validating as many lines as possible using RT-qPCR and phenotypic analyses, and developing tools and web resources for identifying RNAi lines and retrieving existing information on their quality. With these goals in mind, here we describe in detail the various tools we developed and the status of the collection, which is currently composed of 11,491 lines and covering 71% of Drosophila genes. Data on the characterization of the lines either by RT-qPCR or phenotype is available on a dedicated website, the RNAi Stock Validation and Phenotypes Project (RSVP, http://www.flyrnai.org/RSVP.html), and stocks are available from three stock centers, the Bloomington Drosophila Stock Center (United States), National Institute of Genetics (Japan), and TsingHua Fly Center (China). Copyright © 2015 by the Genetics Society of America.

A Census of Large-scale (≥10 PC), Velocity-coherent, Dense Filaments in the Northern Galactic Plane: Automated Identification Using Minimum Spanning Tree

NASA Astrophysics Data System (ADS)

Wang, Ke; Testi, Leonardo; Burkert, Andreas; Walmsley, C. Malcolm; Beuther, Henrik; Henning, Thomas

2016-09-01

Large-scale gaseous filaments with lengths up to the order of 100 pc are on the upper end of the filamentary hierarchy of the Galactic interstellar medium (ISM). Their association with respect to the Galactic structure and their role in Galactic star formation are of great interest from both an observational and theoretical point of view. Previous “by-eye” searches, combined together, have started to uncover the Galactic distribution of large filaments, yet inherent bias and small sample size limit conclusive statistical results from being drawn. Here, we present (1) a new, automated method for identifying large-scale velocity-coherent dense filaments, and (2) the first statistics and the Galactic distribution of these filaments. We use a customized minimum spanning tree algorithm to identify filaments by connecting voxels in the position-position-velocity space, using the Bolocam Galactic Plane Survey spectroscopic catalog. In the range of 7\\buildrel{\\circ}\\over{.} 5≤slant l≤slant 194^\\circ , we have identified 54 large-scale filaments and derived mass (˜ {10}3{--}{10}5 {M}⊙ ), length (10-276 pc), linear mass density (54-8625 {M}⊙ pc-1), aspect ratio, linearity, velocity gradient, temperature, fragmentation, Galactic location, and orientation angle. The filaments concentrate along major spiral arms. They are widely distributed across the Galactic disk, with 50% located within ±20 pc from the Galactic mid-plane and 27% run in the center of spiral arms. An order of 1% of the molecular ISM is confined in large filaments. Massive star formation is more favorable in large filaments compared to elsewhere. This is the first comprehensive catalog of large filaments that can be useful for a quantitative comparison with spiral structures and numerical simulations.

Optimal Transport Destination for Ischemic Stroke Patients With Unknown Vessel Status: Use of Prehospital Triage Scores.

PubMed

Schlemm, Eckhard; Ebinger, Martin; Nolte, Christian H; Endres, Matthias; Schlemm, Ludwig

2017-08-01

Patients with acute ischemic stroke (AIS) and large vessel occlusion may benefit from direct transportation to an endovascular capable comprehensive stroke center (mothership approach) as opposed to direct transportation to the nearest stroke unit without endovascular therapy (drip and ship approach). The optimal transport strategy for patients with AIS and unknown vessel status is uncertain. The rapid arterial occlusion evaluation scale (RACE, scores ranging from 0 to 9, with higher scores indicating higher stroke severity) correlates with the National Institutes of Health Stroke Scale and was developed to identify patients with large vessel occlusion in a prehospital setting. We evaluate how the RACE scale can help to inform prehospital triage decisions for AIS patients. In a model-based approach, we estimate probabilities of good outcome (modified Rankin Scale score of ≤2 at 3 months) as a function of severity of stroke symptoms and transport times for the mothership approach and the drip and ship approach. We use these probabilities to obtain optimal RACE cutoff scores for different transfer time settings and combinations of treatment options (time-based eligibility for secondary transfer under the drip and ship approach, time-based eligibility for thrombolysis at the comprehensive stroke center under the mothership approach). In our model, patients with AIS are more likely to benefit from direct transportation to the comprehensive stroke center if they have more severe strokes. Values of the optimal RACE cutoff scores range from 0 (mothership for all patients) to >9 (drip and ship for all patients). Shorter transfer times and longer door-to-needle and needle-to-transfer (door out) times are associated with lower optimal RACE cutoff scores. Use of RACE cutoff scores that take into account transport times to triage AIS patients to the nearest appropriate hospital may lead to improved outcomes. Further studies should examine the feasibility of translation into clinical practice. © 2017 American Heart Association, Inc.

Communication Skills Training for Physicians Improves Patient Satisfaction.

PubMed

Boissy, Adrienne; Windover, Amy K; Bokar, Dan; Karafa, Matthew; Neuendorf, Katie; Frankel, Richard M; Merlino, James; Rothberg, Michael B

2016-07-01

Skilled physician communication is a key component of patient experience. Large-scale studies of exposure to communication skills training and its impact on patient satisfaction have not been conducted. We aimed to examine the impact of experiential relationship-centered physician communication skills training on patient satisfaction and physician experience. This was an observational study. The study was conducted at a large, multispecialty academic medical center. Participants included 1537 attending physicians who participated in, and 1951 physicians who did not participate in, communication skills training between 1 August 2013 and 30 April 2014. An 8-h block of interactive didactics, live or video skill demonstrations, and small group and large group skills practice sessions using a relationship-centered model. Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS), Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CGCAHPS), Jefferson Scale of Empathy (JSE), Maslach Burnout Inventory (MBI), self-efficacy, and post course satisfaction. Following the course, adjusted overall CGCAHPS scores for physician communication were higher for intervention physicians than for controls (92.09 vs. 91.09, p < 0.03). No significant interactions were noted between physician specialty or baseline CGCAHPS and improvement following the course. Significant improvement in the post-course HCAHPS Respect domain adjusted mean was seen in intervention versus control groups (91.08 vs. 88.79, p = 0.02) and smaller, non-statistically significant improvements were also seen for adjusted HCAHPS communication scores (83.95 vs. 82.73, p = 0.22). Physicians reported high course satisfaction and showed significant improvement in empathy (116.4 ± 12.7 vs. 124 ± 11.9, p < 0.001) and burnout, including all measures of emotional exhaustion, depersonalization, and personal accomplishment. Less depersonalization and greater personal accomplishment were sustained for at least 3 months. System-wide relationship-centered communication skills training improved patient satisfaction scores, improved physician empathy, self-efficacy, and reduced physician burnout. Further research is necessary to examine longer-term sustainability of such interventions.

Measurement of the integrated Luminosities of cross-section scan data samples around the {\\rm{\\psi }}(3770) mass region

NASA Astrophysics Data System (ADS)

Ablikim, M.; Achasov, M. N.; Ahmed, S.; Albrecht, M.; Alekseev, M.; Amoroso, A.; An, F. F.; An, Q.; Bai, Y.; Bakina, O.; Baldini Ferroli, R.; Ban, Y.; Begzsuren, K.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chang, W. L.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, P. L.; Chen, S. J.; Chen, X. R.; Chen, Y. B.; Chu, X. K.; Cibinetto, G.; Cossio, F.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fang, J.; Fang, S. S.; Fang, Y.; Farinelli, R.; Fava, L.; Fegan, S.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Y. G.; Gao, Z.; Garillon, B.; Garzia, I.; Gilman, A.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, L. M.; Gu, M. H.; Gu, Y. T.; Guo, A. Q.; Guo, L. B.; Guo, R. P.; Guo, Y. P.; Guskov, A.; Haddadi, Z.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; He, X. Q.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Z. L.; Hussain, T.; Ikegami Andersson, W.; Irshad, M.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Jin, Y.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Khan, T.; Khoukaz, A.; Kiese, P.; Kliemt, R.; Koch, L.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuemmel, M.; Kuessner, M.; Kupsc, A.; Kurth, M.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Lavezzi, L.; Leiber, S.; Leithoff, H.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, J. W.; Li, K. J.; Li, Kang; Li, Ke; Li, Lei; Li, P. L.; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Liao, L. Z.; Libby, J.; Lin, C. X.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, D. Y.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. L.; Liu, H. M.; Liu, Huanhuan; Liu, Huihui; Liu, J. B.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, Ke; Liu, L. D.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Long, Y. F.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, X. L.; Lusso, S.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mangoni, A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Meng, Z. X.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Morello, G.; Muchnoi, N. Yu; Muramatsu, H.; Mustafa, A.; Nakhoul, S.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Papenbrock, M.; Patteri, P.; Pelizaeus, M.; Pellegrino, J.; Peng, H. P.; Peng, Z. Y.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Pitka, A.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qi, T. Y.; Qian, S.; Qiao, C. F.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Richter, M.; Ripka, M.; Rolo, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Shan, W.; Shan, X. Y.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Shi, X.; Song, J. J.; Song, W. M.; Song, X. Y.; Sosio, S.; Sowa, C.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, L.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. K.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tan, Y. T.; Tang, C. J.; Tang, G. Y.; Tang, X.; Tapan, I.; Tiemens, M.; Tsednee, B.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, C. W.; Wang, D.; Wang, D. Y.; Wang, Dan; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, Meng; Wang, P.; Wang, P. L.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. Y.; Wang, Zongyuan; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, X.; Xia, Y.; Xiao, D.; Xiao, Y. J.; Xiao, Z. J.; Xie, Y. G.; Xie, Y. H.; Xiong, X. A.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, F.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, S. L.; Yang, Y. H.; Yang, Y. X.; Yang, Yifan; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. F.; Zhang, T. J.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Yang; Zhang, Yao; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, Q.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, A. N.; Zhu, J.; Zhu, J.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

2018-05-01

To investigate the nature of the {{\\psi }}(3770) resonance and to measure the cross section for {{{e}}}+{{{e}}}-\\to {{D}}\\bar{{{D}}}, a cross-section scan data sample, distributed among 41 center-of-mass energy points from 3.73 to 3.89 GeV, was taken with the BESIII detector operated at the BEPCII collider in the year 2010. By analyzing the large angle Bhabha scattering events, we measure the integrated luminosity of the data sample at each center-of-mass energy point. The total integrated luminosity of the data sample is 76.16+/- 0.04+/- 0.61 {pb}}-1, where the first uncertainty is statistical and the second systematic. Supported by National Key Basic Research Program of China (2015CB856700), National Natural Science Foundation of China (NSFC) (11235011, 11335008, 11425524, 11625523, 11635010), the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, the CAS Center for Excellence in Particle Physics (CCEPP), Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (U1332201, U1532257, U1532258), CAS Key Research Program of Frontier Sciences (QYZDJ-SSW-SLH003, QYZDJ-SSW-SLH040), 100 Talents Program of CAS, National 1000 Talents Program of China, INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG under Contracts Nos. Collaborative Research Center CRC 1044, FOR 2359, Istituto Nazionale di Fisica Nucleare, Italy, Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03), Ministry of Development of Turkey (DPT2006K-120470), National Science and Technology fund, The Swedish Research Council, U. S. Department of Energy (DE-FG02-05ER41374, DE-SC-0010118, DE-SC-0010504, DE-SC-0012069), University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0)

Recognizing Axionic Dark Matter by Compton and de Broglie Scale Modulation of Pulsar Timing.

PubMed

De Martino, Ivan; Broadhurst, Tom; Tye, S-H Henry; Chiueh, Tzihong; Schive, Hsi-Yu; Lazkoz, Ruth

2017-12-01

Light axionic dark matter, motivated by string theory, is increasingly favored for the "no weakly interacting massive particle era". Galaxy formation is suppressed below a Jeans scale of ≃10^{8}  M_{⊙} by setting the axion mass to m_{B}∼10^{-22}  eV, and the large dark cores of dwarf galaxies are explained as solitons on the de Broglie scale. This is persuasive, but detection of the inherent scalar field oscillation at the Compton frequency ω_{B}=(2.5  months)^{-1}(m_{B}/10^{-22}  eV) would be definitive. By evolving the coupled Schrödinger-Poisson equation for a Bose-Einstein condensate, we predict the dark matter is fully modulated by de Broglie interference, with a dense soliton core of size ≃150  pc, at the Galactic center. The oscillating field pressure induces general relativistic time dilation in proportion to the local dark matter density and pulsars within this dense core have detectably large timing residuals of ≃400  nsec/(m_{B}/10^{-22}  eV). This is encouraging as many new pulsars should be discovered near the Galactic center with planned radio surveys. More generally, over the whole Galaxy, differences in dark matter density between pairs of pulsars imprints a pairwise Galactocentric signature that can be distinguished from an isotropic gravitational wave background.

Establishment of a National Wind Energy Center at University of Houston

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Su Su

The DOE-supported project objectives are to: establish a national wind energy center (NWEC) at University of Houston and conduct research to address critical science and engineering issues for the development of future large MW-scale wind energy production systems, especially offshore wind turbines. The goals of the project are to: (1) establish a sound scientific/technical knowledge base of solutions to critical science and engineering issues for developing future MW-scale large wind energy production systems, (2) develop a state-of-the-art wind rotor blade research facility at the University of Houston, and (3) through multi-disciplinary research, introducing technology innovations on advanced wind-turbine materials, processing/manufacturingmore » technology, design and simulation, testing and reliability assessment methods related to future wind turbine systems for cost-effective production of offshore wind energy. To achieve the goals of the project, the following technical tasks were planned and executed during the period from April 15, 2010 to October 31, 2014 at the University of Houston: (1) Basic research on large offshore wind turbine systems (2) Applied research on innovative wind turbine rotors for large offshore wind energy systems (3) Integration of offshore wind-turbine design, advanced materials and manufacturing technologies (4) Integrity and reliability of large offshore wind turbine blades and scaled model testing (5) Education and training of graduate and undergraduate students and post- doctoral researchers (6) Development of a national offshore wind turbine blade research facility The research program addresses both basic science and engineering of current and future large wind turbine systems, especially offshore wind turbines, for MW-scale power generation. The results of the research advance current understanding of many important scientific issues and provide technical information for solving future large wind turbines with advanced design, composite materials, integrated manufacturing, and structural reliability and integrity. The educational program have trained many graduate and undergraduate students and post-doctoral level researchers to learn critical science and engineering of wind energy production systems through graduate-level courses and research, and participating in various projects in center’s large multi-disciplinary research. These students and researchers are now employed by the wind industry, national labs and universities to support the US and international wind energy industry. The national offshore wind turbine blade research facility developed in the project has been used to support the technical and training tasks planned in the program to accomplish their goals, and it is a national asset which is available for used by domestic and international researchers in the wind energy arena.« less

Towards Development of Clustering Applications for Large-Scale Comparative Genotyping and Kinship Analysis Using Y-Short Tandem Repeats.

PubMed

Seman, Ali; Sapawi, Azizian Mohd; Salleh, Mohd Zaki

2015-06-01

Y-chromosome short tandem repeats (Y-STRs) are genetic markers with practical applications in human identification. However, where mass identification is required (e.g., in the aftermath of disasters with significant fatalities), the efficiency of the process could be improved with new statistical approaches. Clustering applications are relatively new tools for large-scale comparative genotyping, and the k-Approximate Modal Haplotype (k-AMH), an efficient algorithm for clustering large-scale Y-STR data, represents a promising method for developing these tools. In this study we improved the k-AMH and produced three new algorithms: the Nk-AMH I (including a new initial cluster center selection), the Nk-AMH II (including a new dominant weighting value), and the Nk-AMH III (combining I and II). The Nk-AMH III was the superior algorithm, with mean clustering accuracy that increased in four out of six datasets and remained at 100% in the other two. Additionally, the Nk-AMH III achieved a 2% higher overall mean clustering accuracy score than the k-AMH, as well as optimal accuracy for all datasets (0.84-1.00). With inclusion of the two new methods, the Nk-AMH III produced an optimal solution for clustering Y-STR data; thus, the algorithm has potential for further development towards fully automatic clustering of any large-scale genotypic data.

Multilevel Hierarchical Kernel Spectral Clustering for Real-Life Large Scale Complex Networks

PubMed Central

Mall, Raghvendra; Langone, Rocco; Suykens, Johan A. K.

2014-01-01

Kernel spectral clustering corresponds to a weighted kernel principal component analysis problem in a constrained optimization framework. The primal formulation leads to an eigen-decomposition of a centered Laplacian matrix at the dual level. The dual formulation allows to build a model on a representative subgraph of the large scale network in the training phase and the model parameters are estimated in the validation stage. The KSC model has a powerful out-of-sample extension property which allows cluster affiliation for the unseen nodes of the big data network. In this paper we exploit the structure of the projections in the eigenspace during the validation stage to automatically determine a set of increasing distance thresholds. We use these distance thresholds in the test phase to obtain multiple levels of hierarchy for the large scale network. The hierarchical structure in the network is determined in a bottom-up fashion. We empirically showcase that real-world networks have multilevel hierarchical organization which cannot be detected efficiently by several state-of-the-art large scale hierarchical community detection techniques like the Louvain, OSLOM and Infomap methods. We show that a major advantage of our proposed approach is the ability to locate good quality clusters at both the finer and coarser levels of hierarchy using internal cluster quality metrics on 7 real-life networks. PMID:24949877

Incorporating Geodectic Processing Modules into a Real-Time Earthworm Environment to Enhance NOAA's Tsunami Warning Capability

NASA Astrophysics Data System (ADS)

Macpherson, K. A.

2017-12-01

The National Oceanographic and Atmospheric Administration's National and Pacific Tsunami Warning Centers currently rely on traditional seismic data in order to detect and evaluate potential tsunamigenic earthquakes anywhere on the globe. The first information products disseminated by the centers following a significant seismic event are based solely on seismically-derived earthquake locations and magnitudes, and are issued within minutes of the earthquake origin time. Thus, the rapid and reliable determination of the earthquake magnitude is a critical piece of information needed by the centers to generate the appropriate alert levels. However, seismically-derived magnitudes of large events are plagued by well-known problems, particularly during the first few minutes following the origin time; near-source broad-band instruments may go off scale, and magnitudes tend to saturate until sufficient teleseismic data arrive to represent the long-period signal that characterizes large events. However, geodetic data such as high-rate Global Positioning System (hGPS) displacements and seismogeodetic data that is a combination of collocated hGPS and accelerometer data do not suffer from these limitations. These sensors stay on scale, even for large events, and they record both dynamic and static displacements that may be used to estimate magnitude without saturation. Therefore, there is an ongoing effort to incorporate these data streams into the operations of the tsunami warning centers to enhance current magnitude determination capabilities, and eventually, to invert the geodetic displacements for mechanism and finite-fault information. These later quantities will be useful for tsunami modeling and forecasting. The tsunami warning centers rely on the Earthworm system for real-time data acquisition, so we have developed Earthworm modules for the Magnitude from Peak Ground Displacement (MPGD) algorithm, developed at the University of Washington and the University of California, Berkeley, and a module for a Static Offset Estimator algorithm that was developed by the NASA Jet Propulsion Laboratory. In this presentation we will discuss module architecture and show output computed by replaying both synthetic and historical scenarios in a simulated real-time Earthworm environment.

DIALOG: An executive computer program for linking independent programs

NASA Technical Reports Server (NTRS)

Glatt, C. R.; Hague, D. S.; Watson, D. A.

1973-01-01

A very large scale computer programming procedure called the DIALOG Executive System has been developed for the Univac 1100 series computers. The executive computer program, DIALOG, controls the sequence of execution and data management function for a library of independent computer programs. Communication of common information is accomplished by DIALOG through a dynamically constructed and maintained data base of common information. The unique feature of the DIALOG Executive System is the manner in which computer programs are linked. Each program maintains its individual identity and as such is unaware of its contribution to the large scale program. This feature makes any computer program a candidate for use with the DIALOG Executive System. The installation and use of the DIALOG Executive System are described at Johnson Space Center.

Ancient geodynamics and global-scale hydrology on Mars.

PubMed

Phillips, R J; Zuber, M T; Solomon, S C; Golombek, M P; Jakosky, B M; Banerdt, W B; Smith, D E; Williams, R M; Hynek, B M; Aharonson, O; Hauck , S A

2001-03-30

Loading of the lithosphere of Mars by the Tharsis rise explains much of the global shape and long-wavelength gravity field of the planet, including a ring of negative gravity anomalies and a topographic trough around Tharsis, as well as gravity anomaly and topographic highs centered in Arabia Terra and extending northward toward Utopia. The Tharsis-induced trough and antipodal high were largely in place by the end of the Noachian Epoch and exerted control on the location and orientation of valley networks. The release of carbon dioxide and water accompanying the emplacement of approximately 3 x 10(8) cubic kilometers of Tharsis magmas may have sustained a warmer climate than at present, enabling the formation of ancient valley networks and fluvial landscape denudation in and adjacent to the large-scale trough.

A Simple Non-equilibrium Model of Star Formation and Scatter in the Kennicutt-Schmidt Relation and Star Formation Efficiencies in Galaxies

NASA Astrophysics Data System (ADS)

Orr, Matthew; Hopkins, Philip F.

2018-06-01

I will present a simple model of non-equilibrium star formation and its relation to the scatter in the Kennicutt-Schmidt relation and large-scale star formation efficiencies in galaxies. I will highlight the importance of a hierarchy of timescales, between the galaxy dynamical time, local free-fall time, the delay time of stellar feedback, and temporal overlap in observables, in setting the scatter of the observed star formation rates for a given gas mass. Further, I will talk about how these timescales (and their associated duty-cycles of star formation) influence interpretations of the large-scale star formation efficiency in reasonably star-forming galaxies. Lastly, the connection with galactic centers and out-of-equilibrium feedback conditions will be mentioned.

Large-scale variations in observed Antarctic Sea ice extent and associated atmospheric circulation

NASA Technical Reports Server (NTRS)

Cavalieri, D. J.; Parkinson, C. L.

1981-01-01

The 1974 Antarctic large scale sea ice extent is studied from data from Nimbus 2 and 5 and temperature and sea level pressure fields from the Australian Meteorological Data Set. Electrically Scanning Microwave Radiometer data were three-day averaged and compared with 1000 mbar atmospheric pressure and sea level pressure data, also in three-day averages. Each three-day period was subjected to a Fourier analysis and included the mean latitude of the ice extent and the phases and percent variances in terms of the first six Fourier harmonics. Centers of low pressure were found to be generally east of regions which displayed rapid ice growth, and winds acted to extend the ice equatorward. An atmospheric response was also noted as caused by the changing ice cover.

Policy approaches to renewable energy investment in the Mediterranean region

NASA Astrophysics Data System (ADS)

Patt, A.; Komendantova, N.; Battaglini, A.; Lilliestam, J.; Williges, K.

2009-04-01

Europe's climate policy objective of 20% renewable energy by 2020, and the call by the IPCC to reduce greenhouse gas emissions by 80% by 2050, pose major challenges for the European Union. Several policy options are available to move towards these objectives. In this paper, we will address the most critical policy and governance issues associated with one particular approach to scaling up renewable energy resources: reliance on large-scale energy generation facilities outside the European continent, such as onshore and offshore wind farms and concentrating solar power (CSP) facilities in the Mediterranean region. Several feasibility studies completed over the past three years (German Aerospace Center 2006; German Aerospace Center 2005; Czisch, Elektrotechnik 2005, p. 488; Lorenz, Pinner, Seitz, McKinsey Quarterly 2008, p.10; German Aerospace Center 2005; Knies 2008, The Club of Rome; Khosla, Breaking the Climate Deadlock Briefing Papers, 2008, p.19) have convincingly demonstrated that large-scale wind and CSP projects ought to be very attractive for a number of reasons, including cost, reliability of power supply, and technological maturity. According to these studies it would be technically possible for Europe to rely on large-scale wind and CSP for the majority of its power needs by 2050—indeed enough to completely replace its reliance on fossil fuels for power generation—at competitive cost over its current, carbon intensive system. While it has been shown to be technically feasible to develop renewable resources in North Africa to account for a large share of Europe's energy needs, doing so would require sustained double digit rates of growth in generating and long-distance transmission capacity, and would potentially require a very different high voltage grid architecture within Europe. Doing so at a large scale could require enormous up-front investments in technical capacity, financial instruments and human resources. What are the policy instruments best suited to achieving such growth quickly and smoothly? What bottlenecks—in terms of supply chains, human capital, finance, and transmission capacity—need to be anticipated and addressed if the rate of capacity growth is to be sustained over several decades? What model of governance would create a safe investment climate in consistence with new EU legislation (i.e. EU Renewable Energy Directive) as well as expected post-Kyoto targets and mechanisms? The material that we present here is based on a series of workshops held between November 2008 and January 2009, in which a wide range of stakeholders expressed their views about the fundamental needs for policy intervention. Supplementing the results from these workshops have been additional expert interviews, and basic financial modeling. One of the interesting results from this research is the need for a multi-pronged approach. First, there is a need for a support scheme, potentially compatible with in all cases supplementing the EU REN Directive, that would create a stable market for North African electricity in Europe. Second, there is a need for policies that facilitate the formation of public private partnerships in North Africa, as the specific investment vehicle, as a way to manage some of the uncertainties associated with large-scale investments in the region. Third, attention has to be paid to the development of supply chains within the Mediterranean region, as a way of ensuring the compatibility of such investments with sustainable development.

Heritage Gallery

NASA Technical Reports Server (NTRS)

2002-01-01

Marshall Space Flight Center's (MSFC's) building 4200 hosts a new spaceflight history museum referred to as the Heritage Gallery, allowing employees and visitors alike to have the opportunity to experience history first hand. On display are many models of launch vehicles and spacecraft that have made the center famous. It features a full-scale mockup of the lunar roving vehicle, three built-in multimedia displays, a large theater screen, and two glass cases that house memorabilia such as personal items belonging to Wernher von Braun, MSFC's first Center Director. The new Heritage Gallery features the accomplishments of several past and present members of the Marshall team. Attending the ribbon cutting ceremony are: (left to right) Gerhard Reisig; Cort Durocher, executive director of the American Institute of Aeronautics and Astronautics; Ernst Stuhlinger; Konrad Darnenburg; Werner Dahm; Walter Jacobi; and host of event, Center Director Art Stephenson.

Around Marshall

NASA Image and Video Library

2002-10-30

Marshall Space Flight Center's (MSFC's) building 4200 hosts a new spaceflight history museum referred to as the Heritage Gallery, allowing employees and visitors alike to have the opportunity to experience history first hand. On display are many models of launch vehicles and spacecraft that have made the center famous. It features a full-scale mockup of the lunar roving vehicle, three built-in multimedia displays, a large theater screen, and two glass cases that house memorabilia such as personal items belonging to Wernher von Braun, MSFC's first Center Director. The new Heritage Gallery features the accomplishments of several past and present members of the Marshall team. Attending the ribbon cutting ceremony are: (left to right) Gerhard Reisig; Cort Durocher, executive director of the American Institute of Aeronautics and Astronautics; Ernst Stuhlinger; Konrad Darnenburg; Werner Dahm; Walter Jacobi; and host of event, Center Director Art Stephenson.

Three-dimensional constrained variational analysis: Approach and application to analysis of atmospheric diabatic heating and derivative fields during an ARM SGP intensive observational period

NASA Astrophysics Data System (ADS)

Tang, Shuaiqi; Zhang, Minghua

2015-08-01

Atmospheric vertical velocities and advective tendencies are essential large-scale forcing data to drive single-column models (SCMs), cloud-resolving models (CRMs), and large-eddy simulations (LESs). However, they cannot be directly measured from field measurements or easily calculated with great accuracy. In the Atmospheric Radiation Measurement Program (ARM), a constrained variational algorithm (1-D constrained variational analysis (1DCVA)) has been used to derive large-scale forcing data over a sounding network domain with the aid of flux measurements at the surface and top of the atmosphere (TOA). The 1DCVA algorithm is now extended into three dimensions (3DCVA) along with other improvements to calculate gridded large-scale forcing data, diabatic heating sources (Q1), and moisture sinks (Q2). Results are presented for a midlatitude cyclone case study on 3 March 2000 at the ARM Southern Great Plains site. These results are used to evaluate the diabatic heating fields in the available products such as Rapid Update Cycle, ERA-Interim, National Centers for Environmental Prediction Climate Forecast System Reanalysis, Modern-Era Retrospective Analysis for Research and Applications, Japanese 55-year Reanalysis, and North American Regional Reanalysis. We show that although the analysis/reanalysis generally captures the atmospheric state of the cyclone, their biases in the derivative terms (Q1 and Q2) at regional scale of a few hundred kilometers are large and all analyses/reanalyses tend to underestimate the subgrid-scale upward transport of moist static energy in the lower troposphere. The 3DCVA-gridded large-scale forcing data are physically consistent with the spatial distribution of surface and TOA measurements of radiation, precipitation, latent and sensible heat fluxes, and clouds that are better suited to force SCMs, CRMs, and LESs. Possible applications of the 3DCVA are discussed.

[Prospect of the Advanced Life Support Program Breadboard Project at Kennedy Space Center in USA].

PubMed

Guo, S S; Ai, W D

2001-04-01

The Breadboard Project at Kennedy Space Center in NASA of USA was focused on the development of the bioregenerative life support components, crop plants for water, air, and food production and bioreactors for recycling of wastes. The keystone of the Breadboard Project was the Biomass Production Chamber (BPC), which was supported by 15 environmentally controlled chambers and several laboratory facilities holding a total area of 2150 m2. In supporting the Advanced Life Support Program (ALS Program), the Project utilizes these facilities for large-scale testing of components and development of required technologies for human-rated test-beds at Johnson Space Center in NASA, in order to enable a Lunar and a Mars mission finally.

Deep JVLA Imaging of GOODS-N at 20 cm

NASA Astrophysics Data System (ADS)

Owen, Frazer N.

2018-04-01

New wideband continuum observations in the 1–2 GHz band of the GOODS-N field using NSF’s Karl G. Jansky Very Large Array (VLA) are presented. The best image with an effective frequency of 1525 MHz reaches an rms noise in the field center of 2.2 μJy, with 1.″6 resolution. A catalog of 795 sources is presented covering a radius of 9 arcminutes centered near the nominal center for the GOODS-N field, very near the nominal VLA pointing center for the observations. Optical/NIR identifications and redshift estimates both from ground-based and HST observations are discussed. Using these optical/NIR data, it is most likely that fewer than 2% of the sources without confusion problems do not have a correct identification. A large subset of the detected sources have radio sizes >1″. It is shown that the radio orientations for such sources correlate well with the HST source orientations, especially for z < 1. This suggests that a least a large subset of the 10 kpc-scale disks of luminous infrared/ultraluminous infrared galaxies (LIRG/ULIRG) have strong star formation, not just in the nucleus. For the half of the objects with z > 1, the sample must be some mixture of very high star formation rates, typically 300 M ⊙ yr‑1, assuming pure star formation, and an active galactic nucleus (AGN) or a mixed AGN/star formation population.

Development of a system for classification of pork loins for tenderness using visible and near-infrared reflectance spectroscopy

USDA-ARS?s Scientific Manuscript database

Boneless pork loins (n = 901) were evaluated either on the loin boning and trimming line of large-scale commercial plants (n = 465) or at the U.S. Meat Animal Research Center abattoir (n = 436). Exposed LM on the ventral side of boneless loins was evaluated with visible and near-infrared spectrosco...

2001 Industry Studies: Electronics

DTIC Science & Technology

2001-01-01

Center, Dallas, TX Northrop Grumman Corp, Electronic Sensors & Systems, Baltimore, MD International Acer Incorporated, Hsin Chu, Taiwan Aerospace...manufacturing. Many of the large-scale fabrication foundries are offshore in such countries as Taiwan, Singapore and Malaysia .5 - 5 - The largest market for...done in the US. However, more of the actual mass manufacturing of the chips are done in Taiwan, Singapore, and Malaysia . A new semiconductor facility

Secondary Analysis of State Assessment Data: Why We Can't Say Much about Students with Disabilities. Technical Report 10.

ERIC Educational Resources Information Center

McGrew, Kevin S.; And Others

This report summarizes activities of the National Center on Educational Outcomes directed at producing a report on the status of students with disabilities from the secondary analysis of state-collected achievement data. Although 27 states reported that large-scale achievement data were available for some students with disabilities, potentially…

Pathways--A Case of Large-Scale Implementation of Evidence-Based Practice in Scientific Inquiry-Based Science Education

ERIC Educational Resources Information Center

Sotiriou, Sofoklis; Bybee, Rodger W.; Bogner, Franz X.

2017-01-01

The fundamental pioneering ideas about student-centered, inquiry-based learning initiatives are differing in Europe and the US. The latter had initiated various top-down schemes that have led to well-defined standards, while in Europe, with its some 50 independent educational systems, a wide variety of approaches has been evolved. In this present…

Application of Evidence-Centered Assessment Design to the Advanced Placement Redesign: A Graphic Restatement

ERIC Educational Resources Information Center

Bejar, Isaac I.

2010-01-01

The foregoing articles constitute what I consider a comprehensive and clear description of the redesign process of a major assessment. The articles serve to illustrate the problems that will need to be addressed by large-scale assessments in the twenty-first century. Primary among them is how to organize the development of such assessments to meet…

Psychosocial Factors in Adolescent and Young Adult Self-Reported Depressive Symptoms: Causal or Correlational Associations?

ERIC Educational Resources Information Center

Steinhausen, Hans-Christoph; Haslimeier, Claudia; Metzke, Christa Winkler

2007-01-01

Using a large longitudinal representative community sample, this study identified three groups of subjects who were depressed either in pre-adolescence, late adolescence or early adulthood, and matched by age and gender to controls without depression. The 90th percentile on one or two self-reported symptom scales [i. e. the Center for…

Children as Artists: The Preschool as a Community of Creative Practice

ERIC Educational Resources Information Center

Cutcher, Alexandra; Boyd, Wendy

2016-01-01

Picasso once famously said "All children are artists. The problem is how to remain an artist once he grows up." This visual inquiry is engaged through a community of creative practice in two rural children's centers where the researchers along with 4- and 5-year-old children collaborated to create a large-scale canvas and several smaller…

Complex dynamics and empirical evidence (Invited Paper)

NASA Astrophysics Data System (ADS)

Delli Gatti, Domenico; Gaffeo, Edoardo; Giulioni, Gianfranco; Gallegati, Mauro; Kirman, Alan; Palestrini, Antonio; Russo, Alberto

2005-05-01

Standard macroeconomics, based on a reductionist approach centered on the representative agent, is badly equipped to explain the empirical evidence where heterogeneity and industrial dynamics are the rule. In this paper we show that a simple agent-based model of heterogeneous financially fragile agents is able to replicate a large number of scaling type stylized facts with a remarkable degree of statistical precision.

Towards a High Quality High School Workforce: A Longitudinal, Demographic Analysis of U.S. Public School Physics Teachers

ERIC Educational Resources Information Center

Rushton, Gregory T.; Rosengrant, David; Dewar, Andrew; Shah, Lisa; Ray, Herman E.; Sheppard, Keith; Watanabe, Lynn

2017-01-01

Efforts to improve the number and quality of the high school physics teaching workforce have taken several forms, including those sponsored by professional organizations. Using a series of large-scale teacher demographic data sets from the National Center for Education Statistics (NCES), this study sought to investigate trends in teacher quality…

Tree species associations of Pinus echinata mill. over a large-scale sampling regime on the interior highlands of Arkansas

Treesearch

James F., Jr. Rosson

2007-01-01

The Interior Highlands physiographic province of Arkansas is considered the ecological center of the geographic distribution of shortleaf pine (Pinus echinata Mill.). I used data from the U.S. Forest Service, Forest Inventory and Analysis (FIA) program to identify the major tree species associates of P. echinata across this 66,700-...

Efficient Generation of an Array of Single Silicon-Vacancy Defects in Silicon Carbide

NASA Astrophysics Data System (ADS)

Wang, Junfeng; Zhou, Yu; Zhang, Xiaoming; Liu, Fucai; Li, Yan; Li, Ke; Liu, Zheng; Wang, Guanzhong; Gao, Weibo

2017-06-01

Color centers in silicon carbide have increasingly attracted attention in recent years owing to their excellent properties such as single-photon emission, good photostability, and long spin-coherence time even at room temperature. As compared to diamond, which is widely used for hosting nitrogen-vacancy centers, silicon carbide has an advantage in terms of large-scale, high-quality, and low-cost growth, as well as an advanced fabrication technique in optoelectronics, leading to prospects for large-scale quantum engineering. In this paper, we report an experimental demonstration of the generation of a single-photon-emitter array through ion implantation. VSi defects are generated in predetermined locations with high generation efficiency (approximately 19 % ±4 % ). The single emitter probability reaches approximately 34 % ±4 % when the ion-implantation dose is properly set. This method serves as a critical step in integrating single VSi defect emitters with photonic structures, which, in turn, can improve the emission and collection efficiency of VSi defects when they are used in a spin photonic quantum network. On the other hand, the defects are shallow, and they are generated about 40 nm below the surface which can serve as a critical resource in quantum-sensing applications.

Auxiliary basis expansions for large-scale electronic structure calculations

PubMed Central

Jung, Yousung; Sodt, Alex; Gill, Peter M. W.; Head-Gordon, Martin

2005-01-01

One way to reduce the computational cost of electronic structure calculations is to use auxiliary basis expansions to approximate four-center integrals in terms of two- and three-center integrals, usually by using the variationally optimum Coulomb metric to determine the expansion coefficients. However, the long-range decay behavior of the auxiliary basis expansion coefficients has not been characterized. We find that this decay can be surprisingly slow. Numerical experiments on linear alkanes and a toy model both show that the decay can be as slow as 1/r in the distance between the auxiliary function and the fitted charge distribution. The Coulomb metric fitting equations also involve divergent matrix elements for extended systems treated with periodic boundary conditions. An attenuated Coulomb metric that is short-range can eliminate these oddities without substantially degrading calculated relative energies. The sparsity of the fit coefficients is assessed on simple hydrocarbon molecules and shows quite early onset of linear growth in the number of significant coefficients with system size using the attenuated Coulomb metric. Hence it is possible to design linear scaling auxiliary basis methods without additional approximations to treat large systems. PMID:15845767

Changing classroom designs: Easy; Changing instructors' pedagogies: Not so easy...

NASA Astrophysics Data System (ADS)

Lasry, Nathaniel; Charles, Elizabeth; Whittaker, Chris; Dedic, Helena; Rosenfield, Steven

2013-01-01

Technology-rich student-centered classrooms such as SCALE-UP and TEAL are designed to actively engage students. We examine what happens when instructors adopt the classroom but not the pedagogy that goes with it. We measure the effect of using socio-technological spaces on students' conceptual change and compare learning gains made in groups using different pedagogies (active learning vs. conventional instruction). We also correlate instructors' self-reported instructional approach (teacher-centered, student-centered) with their classes' normalized FCI gains. We find that technology-rich spaces are only effective when implemented with student-centered active pedagogies. In their absence, the technology-rich classroom is not significantly different from conventional teacher-centered classrooms. We also find that instructors' self-reported perception of student-centeredness accounts for a large fraction of the variance (r2 = 0.83) in their class' average normalized gain. Adopting student-centered pedagogies appears to be a necessary condition for the effective use of technology-rich spaces. However, adopting a new pedagogy seems more difficult than adopting new technology.

Disruption of posteromedial large-scale neural communication predicts recovery from coma.

PubMed

Silva, Stein; de Pasquale, Francesco; Vuillaume, Corine; Riu, Beatrice; Loubinoux, Isabelle; Geeraerts, Thomas; Seguin, Thierry; Bounes, Vincent; Fourcade, Olivier; Demonet, Jean-Francois; Péran, Patrice

2015-12-08

We hypothesize that the major consciousness deficit observed in coma is due to the breakdown of long-range neuronal communication supported by precuneus and posterior cingulate cortex (PCC), and that prognosis depends on a specific connectivity pattern in these networks. We compared 27 prospectively recruited comatose patients who had severe brain injury (Glasgow Coma Scale score <8; 14 traumatic and 13 anoxic cases) with 14 age-matched healthy participants. Standardized clinical assessment and fMRI were performed on average 4 ± 2 days after withdrawal of sedation. Analysis of resting-state fMRI connectivity involved a hypothesis-driven, region of interest-based strategy. We assessed patient outcome after 3 months using the Coma Recovery Scale-Revised (CRS-R). Patients who were comatose showed a significant disruption of functional connectivity of brain areas spontaneously synchronized with PCC, globally notwithstanding etiology. The functional connectivity strength between PCC and medial prefrontal cortex (mPFC) was significantly different between comatose patients who went on to recover and those who eventually scored an unfavorable outcome 3 months after brain injury (Kruskal-Wallis test, p < 0.001; linear regression between CRS-R and PCC-mPFC activity coupling at rest, Spearman ρ = 0.93, p < 0.003). In both etiology groups (traumatic and anoxic), changes in the connectivity of PCC-centered, spontaneously synchronized, large-scale networks account for the loss of external and internal self-centered awareness observed during coma. Sparing of functional connectivity between PCC and mPFC may predict patient outcome, and further studies are needed to substantiate this potential prognosis biomarker. © 2015 American Academy of Neurology.

KSC-2011-8244

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida travels northbound along Kennedy Parkway toward NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

NASA Automated Fiber Placement Capabilities: Similar Systems, Complementary Purposes

NASA Technical Reports Server (NTRS)

Wu, K. Chauncey; Jackson, Justin R.; Pelham, Larry I.; Stewart, Brian K.

2015-01-01

New automated fiber placement systems at the NASA Langley Research Center and NASA Marshall Space Flight Center provide state-of-art composites capabilities to these organizations. These systems support basic and applied research at Langley, complementing large-scale manufacturing and technology development at Marshall. These systems each consist of a multi-degree of freedom mobility platform including a commercial robot, a commercial tool changer mechanism, a bespoke automated fiber placement end effector, a linear track, and a rotational tool support structure. In addition, new end effectors with advanced capabilities may be either bought or developed with partners in industry and academia to extend the functionality of these systems. These systems will be used to build large and small composite parts in support of the ongoing NASA Composites for Exploration Upper Stage Project later this year.

Assessing Hydrological and Energy Budgets in Amazonia through Regional Downscaling, and Comparisons with Global Reanalysis Products

NASA Astrophysics Data System (ADS)

Nunes, A.; Ivanov, V. Y.

2014-12-01

Although current global reanalyses provide reasonably accurate large-scale features of the atmosphere, systematic errors are still found in the hydrological and energy budgets of such products. In the tropics, precipitation is particularly challenging to model, which is also adversely affected by the scarcity of hydrometeorological datasets in the region. With the goal of producing downscaled analyses that are appropriate for a climate assessment at regional scales, a regional spectral model has used a combination of precipitation assimilation with scale-selective bias correction. The latter is similar to the spectral nudging technique, which prevents the departure of the regional model's internal states from the large-scale forcing. The target area in this study is the Amazon region, where large errors are detected in reanalysis precipitation. To generate the downscaled analysis, the regional climate model used NCEP/DOE R2 global reanalysis as the initial and lateral boundary conditions, and assimilated NOAA's Climate Prediction Center (CPC) MORPHed precipitation (CMORPH), available at 0.25-degree resolution, every 3 hours. The regional model's precipitation was successfully brought closer to the observations, in comparison to the NCEP global reanalysis products, as a result of the impact of a precipitation assimilation scheme on cumulus-convection parameterization, and improved boundary forcing achieved through a new version of scale-selective bias correction. Water and energy budget terms were also evaluated against global reanalyses and other datasets.

Advanced Hypervelocity Aerophysics Facility Workshop

NASA Technical Reports Server (NTRS)

Witcofski, Robert D. (Compiler); Scallion, William I. (Compiler)

1989-01-01

The primary objective of the workshop was to obtain a critical assessment of a concept for a large, advanced hypervelocity ballistic range test facility powered by an electromagnetic launcher, which was proposed by the Langley Research Center. It was concluded that the subject large-scale facility was feasible and would provide the required ground-based capability for performing tests at entry flight conditions (velocity and density) on large, complex, instrumented models. It was also concluded that advances in remote measurement techniques and particularly onboard model instrumentation, light-weight model construction techniques, and model electromagnetic launcher (EML) systems must be made before any commitment for the construction of such a facility can be made.

Development and psychometric characteristics of the SCI-QOL Pressure Ulcers scale and short form.

PubMed

Kisala, Pamela A; Tulsky, David S; Choi, Seung W; Kirshblum, Steven C

2015-05-01

To develop a self-reported measure of the subjective impact of pressure ulcers on health-related quality of life (HRQOL) in individuals with spinal cord injury (SCI) as part of the SCI quality of life (SCI-QOL) measurement system. Grounded-theory based qualitative item development methods, large-scale item calibration testing, confirmatory factor analysis (CFA), and item response theory-based psychometric analysis. Five SCI Model System centers and one Department of Veterans Affairs medical center in the United States. Adults with traumatic SCI. SCI-QOL Pressure Ulcers scale. 189 individuals with traumatic SCI who experienced a pressure ulcer within the past 7 days completed 30 items related to pressure ulcers. CFA confirmed a unidimensional pool of items. IRT analyses were conducted. A constrained Graded Response Model with a constant slope parameter was used to estimate item thresholds for the 12 retained items. The 12-item SCI-QOL Pressure Ulcers scale is unique in that it is specifically targeted to individuals with spinal cord injury and at every stage of development has included input from individuals with SCI. Furthermore, use of CFA and IRT methods provide flexibility and precision of measurement. The scale may be administered in its entirety or as a 7-item "short form" and is available for both research and clinical practice.

Subsonic Dynamics of Stardust Sample Return Capsule

NASA Technical Reports Server (NTRS)

Mitcheltree, Robert A.; Fremaux, Charles M.

1997-01-01

Subsonic dynamic stability tests performed in the NASA Langley 20-Foot Vertical Spin-Tunnel on a 0.238 scale model of the Stardust Sample Return Capsule are discussed. The tests reveal that the blunted 60 degree half-angle cone capsule is dynamically unstable at low subsonic conditions due to the aft location of the center-of-gravity (0.351 body diameters back from the nose). The divergent behavior of the capsule continued when the center-of-gravity was moved to 0.337 and 0.313 body diameters back from the nose. When the center-of-gravity was moved further forward to 0.290 body diameters back from the nose, the vehicle established itself in a limit cycle with amplitude around 10 degrees. Two afterbody modifications were examined which proved unsuccessful in alleviating the instability of the original design. Finally, the addition of different sized parachutes was examined as a means to stabilize the vehicle. The parachute tests indicate that a parachute with equivalent full scale drag area of at least 2.24 ft. is necessary to assure large perturbations are damped.

Statistical Analysis of Acoustic Wave Power and Flows around Solar Active Regions

NASA Astrophysics Data System (ADS)

Rabello-Soares, M. Cristina; Bogart, Richard S.; Scherrer, Philip H.

2018-05-01

We analyze the effect of a sunspot in its quiet surroundings applying a helioseismic technique on almost three years of Helioseismic and Magnetic Imager (HMI) observations obtained during solar cycle 24 to further study the sunspot structure below the solar surface. The attenuation of acoustic waves with frequencies lower than 4.2 mHz depends more strongly on the wave direction at a distance of 6°–7° from the sunspot center. The amplification of higher frequency waves is highest 6° away from the active region and is largely independent of the wave’s direction. We observe a mean clockwise flow around active regions, the angular speed of which decreases exponentially with distance and has a coefficient close to ‑0.7 degree‑1. The observed horizontal flow in the direction of the nearby active region agrees with a large-scale circulation around the sunspot in the shape of cylindrical shell. The center of the shell seems to be centered around 7° from the sunspot center, where we observe an inflow close to the surface down to ∼2 Mm, followed by an outflow at deeper layers until at least 7 Mm.

Small-scale behavior in distorted turbulent boundary layers at low Reynolds number

NASA Technical Reports Server (NTRS)

Saddoughi, Seyed G.

1994-01-01

During the last three years we have conducted high- and low-Reynolds-number experiments, including hot-wire measurements of the velocity fluctuations, in the test-section-ceiling boundary layer of the 80- by 120-foot Full-Scale Aerodynamics Facility at NASA Ames Research Center, to test the local-isotropy predictions of Kolmogorov's universal equilibrium theory. This hypothesis, which states that at sufficiently high Reynolds numbers the small-scale structures of turbulent motions are independent of large-scale structures and mean deformations, has been used in theoretical studies of turbulence and computational methods such as large-eddy simulation; however, its range of validity in shear flows has been a subject of controversy. The present experiments were planned to enhance our understanding of the local-isotropy hypothesis. Our experiments were divided into two sets. First, measurements were taken at different Reynolds numbers in a plane boundary layer, which is a 'simple' shear flow. Second, experiments were designed to address this question: will our criteria for the existence of local isotropy hold for 'complex' nonequilibrium flows in which extra rates of mean strain are added to the basic mean shear?

A curvature-based weighted fuzzy c-means algorithm for point clouds de-noising

NASA Astrophysics Data System (ADS)

Cui, Xin; Li, Shipeng; Yan, Xiutian; He, Xinhua

2018-04-01

In order to remove the noise of three-dimensional scattered point cloud and smooth the data without damnify the sharp geometric feature simultaneity, a novel algorithm is proposed in this paper. The feature-preserving weight is added to fuzzy c-means algorithm which invented a curvature weighted fuzzy c-means clustering algorithm. Firstly, the large-scale outliers are removed by the statistics of r radius neighboring points. Then, the algorithm estimates the curvature of the point cloud data by using conicoid parabolic fitting method and calculates the curvature feature value. Finally, the proposed clustering algorithm is adapted to calculate the weighted cluster centers. The cluster centers are regarded as the new points. The experimental results show that this approach is efficient to different scale and intensities of noise in point cloud with a high precision, and perform a feature-preserving nature at the same time. Also it is robust enough to different noise model.

A single-stage optical load-balanced switch for data centers.

PubMed

Huang, Qirui; Yeo, Yong-Kee; Zhou, Luying

2012-10-22

Load balancing is an attractive technique to achieve maximum throughput and optimal resource utilization in large-scale switching systems. However current electronic load-balanced switches suffer from severe problems in implementation cost, power consumption and scaling. To overcome these problems, in this paper we propose a single-stage optical load-balanced switch architecture based on an arrayed waveguide grating router (AWGR) in conjunction with fast tunable lasers. By reuse of the fast tunable lasers, the switch achieves both functions of load balancing and switching through the AWGR. With this architecture, proof-of-concept experiments have been conducted to investigate the feasibility of the optical load-balanced switch and to examine its physical performance. Compared to three-stage load-balanced switches, the reported switch needs only half of optical devices such as tunable lasers and AWGRs, which can provide a cost-effective solution for future data centers.

Solar powered oxygen systems in remote health centers in Papua New Guinea: a large scale implementation effectiveness trial.

PubMed

Duke, Trevor; Hwaihwanje, Ilomo; Kaupa, Magdalynn; Karubi, Jonah; Panauwe, Doreen; Sa'avu, Martin; Pulsan, Francis; Prasad, Peter; Maru, Freddy; Tenambo, Henry; Kwaramb, Ambrose; Neal, Eleanor; Graham, Hamish; Izadnegahdar, Rasa

2017-06-01

Pneumonia is the largest cause of child deaths in Papua New Guinea (PNG), and hypoxaemia is the major complication causing death in childhood pneumonia, and hypoxaemia is a major factor in deaths from many other common conditions, including bronchiolitis, asthma, sepsis, malaria, trauma, perinatal problems, and obstetric emergencies. A reliable source of oxygen therapy can reduce mortality from pneumonia by up to 35%. However, in low and middle income countries throughout the world, improved oxygen systems have not been implemented at large scale in remote, difficult to access health care settings, and oxygen is often unavailable at smaller rural hospitals or district health centers which serve as the first point of referral for childhood illnesses. These hospitals are hampered by lack of reliable power, staff training and other basic services. We report the methodology of a large implementation effectiveness trial involving sustainable and renewable oxygen and power systems in 36 health facilities in remote rural areas of PNG. The methodology is a before-and after evaluation involving continuous quality improvement, and a health systems approach. We describe this model of implementation as the considerations and steps involved have wider implications in health systems in other countries. The implementation steps include: defining the criteria for where such an intervention is appropriate, assessment of power supplies and power requirements, the optimal design of a solar power system, specifications for oxygen concentrators and other oxygen equipment that will function in remote environments, installation logistics in remote settings, the role of oxygen analyzers in monitoring oxygen concentrator performance, the engineering capacity required to sustain a program at scale, clinical guidelines and training on oxygen equipment and the treatment of children with severe respiratory infection and other critical illnesses, program costs, and measurement of processes and outcomes to support continuous quality improvement. This study will evaluate the feasibility and sustainability issues in improving oxygen systems and providing reliable power on a large scale in remote rural settings in PNG, and the impact of this on child mortality from pneumonia over 3 years post-intervention. Taking a continuous quality improvement approach can be transformational for remote health services.

Determination of the number of ψ(3686) events at BESIII

NASA Astrophysics Data System (ADS)

Ablikim, M.; Achasov, M. N.; Ai, X. C.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Baldini Ferroli, R.; Ban, Y.; Bennett, J. V.; Bertani, M.; Bian, J. M.; Boger, E.; Bondarenko, O.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Chu, X. K.; Chu, Y. P.; Cronin-Hennessy, D.; Dai, H. L.; Dai, J. P.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Du, S. X.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, Y.; Fava, L.; Feldbauer, F.; Feng, C. Q.; Fu, C. D.; Gao, Q.; Gao, Y.; Goetzen, K.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, Y. P.; Han, Y. L.; Harris, F. A.; He, K. L.; He, M.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, H. M.; Hu, T.; Huang, G. S.; Huang, J. S.; Huang, L.; Huang, X. T.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. L.; Jiang, X. S.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Kloss, B.; Kopf, B.; Kornicer, M.; Kupsc, A.; Kühn, W.; Lai, W.; Lange, J. S.; Lara, M.; Larin, P.; Li, C. H.; Li, Cheng; Li, D. M.; Li, F.; Li, G.; Li, H. B.; Li, J. C.; Li, Kang; Li, Ke; Li, Lei; Li, P. R.; Li, Q. J.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, X. R.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B. J.; Liu, C. X.; Liu, F. H.; Liu, Fang.; Liu, Feng.; Liu, H. B.; Liu, H. M.; Liu, Huihui.; Liu, J.; Liu, J. P.; Liu, K.; Liu, K. Y.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqiang.; Liu, Zhiqing.; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, H. L.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lv, M.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, Q. M.; Ma, S.; Ma, T.; Ma, X. Y.; Maas, F. E.; Maggiora, M.; Mao, Y. J.; Mao, Z. P.; Messchendorp, J. G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Moriya, K.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Ping, J. L.; Ping, R. G.; Poling, R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Sarantsev, A.; Schoenning, K.; Shan, W.; Shao, M.; Shen, C. P.; Shen, X. Y.; Sheng, H. Y.; Shepherd, M. R.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Toth, D.; Uman, I.; Varner, G. S.; Wang, B.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, Q. J.; Wang, W.; Wang, X. F.; Wang(Yadi, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. Y.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, W. B.; Yan, Y. H.; Yang, H. X.; Yang, Y.; Yang, Y. X.; Ye, H.; Ye, M.; Ye, M. H.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Zafar, A. A.; Zeng, Y.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, L.; Zhang, R.; Zhang, S. H.; Zhang, X. J.; Zhang, X. Y.; Zhang, Y. H.; Zhang, Yao.; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling.; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

2018-02-01

The numbers of ψ(3686) events accumulated by the BESIII detector for the data taken during 2009 and 2012 are determined to be (107.0+/- 0.8)× {10}6 and (341.1+/- 2.1)× {10}6, respectively, by counting inclusive hadronic events, where the uncertainties are systematic and the statistical uncertainties are negligible. The number of events for the sample taken in 2009 is consistent with that of the previous measurement. The total number of ψ(3686) events for the two data taking periods is (448.1+/- 2.9)× {10}6. Supported by the Ministry of Science and Technology of China (2009CB825200), National Natural Science Foundation of China (NSFC) (11235011, 11322544, 11335008, 11425524, 11475207), the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, the Collaborative Innovation Center for Particles and Interactions (CICPI), Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (11179014), Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (11179007, U1232201, U1532257, U1532258), Joint Funds of the National Natural Science Foundation of China (11079008), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, National 1000 Talents Program of China, German Research Foundation DFG (Collaborative Research Center CRC 1044), Istituto Nazionale di Fisica Nucleare, Italy, Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03), Ministry of Development of Turkey (DPT2006K-120470), National Natural Science Foundation of China (11205082), The Swedish Research Council, U. S. Department of Energy (DE-FG02-05ER41374, DE-SC-0010118, DE-SC-0010504), U.S. National Science Foundation, University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0).

Innovation in a Learning Health Care System: Veteran-Directed Home- and Community-Based Services.

PubMed

Garrido, Melissa M; Allman, Richard M; Pizer, Steven D; Rudolph, James L; Thomas, Kali S; Sperber, Nina R; Van Houtven, Courtney H; Frakt, Austin B

2017-11-01

A path-breaking example of the interplay between geriatrics and learning healthcare systems is the Veterans Health Administration's (VHA's) planned roll-out of a program for providing participant-directed home- and community-based services to veterans with cognitive and functional limitations. We describe the design of a large-scale, stepped-wedge, cluster-randomized trial of the Veteran-Directed Home- and Community-Based Services (VD-HCBS) program. From March 2017 through December 2019, up to 77 Veterans Affairs Medical Centers will be randomized to times to begin offering VD-HCBS to veterans at risk of nursing home placement. Services will be provided to community-dwelling participants with support from Aging and Disability Network Agencies. The VHA Partnered Evidence-based Policy Resource Center (PEPReC) is coordinating the evaluation, which includes collaboration from operational stakeholders from the VHA and Administration for Community Living and interdisciplinary researchers from the Center of Innovation in Long-Term Services and Supports and the Center for Health Services Research in Primary Care. For older veterans with functional limitations who are eligible for VD-HCBS, we will evaluate health outcomes (hospitalizations, emergency department visits, nursing home admissions, days at home) and healthcare costs associated with VD-HCBS availability. Learning healthcare systems facilitate diffusion of innovation while enabling rigorous evaluation of effects on patient outcomes. The VHA's randomized rollout of VD-HCBS to veterans at risk of nursing home placement is an example of how to achieve these goals simultaneously. PEPReC's experience designing an evaluation with researchers and operations stakeholders may serve as a framework for others seeking to develop rapid, rigorous, large-scale evaluations of delivery system innovations targeted to older adults. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.

Cloud Properties under Different Synoptic Circulations: Comparison of Radiosonde and Ground-Based Active Remote Sensing Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Jinqiang; Li, Jun; Xia, Xiangao

In this study, long-term (10 years) radiosonde-based cloud data are compared with the ground-based active remote sensing product under six prevailing large-scale synoptic patterns, i.e., cyclonic center (CC), weak pressure pattern (WP), the southeast bottom of cyclonic center (CB), cold front (CF), anticyclone edge (AE) and anticyclone center (AC) over the Southern Great Plains (SGP) site. The synoptic patterns are generated by applying the self-organizing map weather classification method to the daily National Centers for Environmental Protection mean sea level pressure records from the North American Regional Reanalysis. It reveals that the large-scale synoptic circulations can strongly influence the regionalmore » cloud formation, and thereby have impact on the consistency of cloud retrievals from the radiosonde and ground-based cloud product. The total cloud cover at the SGP site is characterized by the least in AC and the most in CF. The minimum and maximum differences between the two cloud methods are 10.3% for CC and 13.3% for WP. Compared to the synoptic patterns characterized by scattered cloudy and clear skies (AE and AC), the agreement of collocated cloud boundaries between the two cloud approaches tends to be better under the synoptic patterns dominated by overcast and cloudy skies (CC, WP and CB). The rainy and windy weather conditions in CF synoptic pattern influence the consistency of the two cloud retrieval methods associated with the limited capabilities inherent to the instruments. As a result, the cloud thickness distribution from the two cloud datasets compares favorably with each other in all synoptic patterns, with relative discrepancy of ≤0.3 km.« less

Cloud Properties under Different Synoptic Circulations: Comparison of Radiosonde and Ground-Based Active Remote Sensing Measurements

DOE PAGES

Zhang, Jinqiang; Li, Jun; Xia, Xiangao; ...

2016-11-28

In this study, long-term (10 years) radiosonde-based cloud data are compared with the ground-based active remote sensing product under six prevailing large-scale synoptic patterns, i.e., cyclonic center (CC), weak pressure pattern (WP), the southeast bottom of cyclonic center (CB), cold front (CF), anticyclone edge (AE) and anticyclone center (AC) over the Southern Great Plains (SGP) site. The synoptic patterns are generated by applying the self-organizing map weather classification method to the daily National Centers for Environmental Protection mean sea level pressure records from the North American Regional Reanalysis. It reveals that the large-scale synoptic circulations can strongly influence the regionalmore » cloud formation, and thereby have impact on the consistency of cloud retrievals from the radiosonde and ground-based cloud product. The total cloud cover at the SGP site is characterized by the least in AC and the most in CF. The minimum and maximum differences between the two cloud methods are 10.3% for CC and 13.3% for WP. Compared to the synoptic patterns characterized by scattered cloudy and clear skies (AE and AC), the agreement of collocated cloud boundaries between the two cloud approaches tends to be better under the synoptic patterns dominated by overcast and cloudy skies (CC, WP and CB). The rainy and windy weather conditions in CF synoptic pattern influence the consistency of the two cloud retrieval methods associated with the limited capabilities inherent to the instruments. As a result, the cloud thickness distribution from the two cloud datasets compares favorably with each other in all synoptic patterns, with relative discrepancy of ≤0.3 km.« less

Measurement of the absolute branching fraction of D+ → K̅0 e+νe via K̅0 → π 0 π 0

NASA Astrophysics Data System (ADS)

Ablikim, M.; Achasov, M. N.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Farinelli, R.; Fava, L.; Fedorov, O.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, X. Y.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, R. P.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Y.; Huang, Z. L.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Y. B.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lü, H. J.; Lü, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lü, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Sarantsev, A.; Savrié, M.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Shi, M.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, W.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. N.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

2016-11-01

By analyzing 2.93 fb-1 data collected at the center-of-mass energy with the BESIII detector, we measure the absolute branching fraction of the semileptonic decay D+ → K̅0 e+νe to be ℬ(D + → K̅0 e+νe) = (8.59 ± 0.14 ± 0.21)% using , where the first uncertainty is statistical and the second systematic. Our result is consistent with previous measurements within uncertainties.. Supported by National Key Basic Research Program of China (2009CB825204, 2015CB856700), National Natural Science Foundation of China (NSFC) (10935007, 11125525, 11235011, 11305180, 11322544, 11335008, 11425524, 11475123), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, CAS Center for Excellence in Particle Physics (CCEPP), Collaborative Innovation Center for Particles and Interactions (CICPI), Joint Large-Scale Scientific Facility Funds of NSFC and CAS (11179007, U1232201, U1332201, U1532101), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, National 1000 Talents Program of China, INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy, Koninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03), Ministry of Development of Turkey (DPT2006K-120470), National Natural Science Foundation of China (NSFC) (11405046, U1332103), Russian Foundation for Basic Research (14-07-91152), Swedish Resarch Council, U. S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-SC0012069, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0).

The transboundary non-renewable Nubian Aquifer System of Chad, Egypt, Libya and Sudan: classical groundwater questions and parsimonious hydrogeologic analysis and modelin

USGS Publications Warehouse

Voss, Clifford I.; Soliman, Safaa M.

2014-01-01

Parsimonious groundwater modeling provides insight into hydrogeologic functioning of the Nubian Aquifer System (NAS), the world’s largest non-renewable groundwater system (belonging to Chad, Egypt, Libya, and Sudan). Classical groundwater-resource issues exist (magnitude and lateral extent of drawdown near pumping centers) with joint international management questions regarding transboundary drawdown. Much of NAS is thick, containing a large volume of high-quality groundwater, but receives insignificant recharge, so water-resource availability is time-limited. Informative aquifer data are lacking regarding large-scale response, providing only local-scale information near pumps. Proxy data provide primary underpinning for understanding regional response: Holocene water-table decline from the previous pluvial period, after thousands of years, results in current oasis/sabkha locations where the water table still intersects the ground. Depletion is found to be controlled by two regional parameters, hydraulic diffusivity and vertical anisotropy of permeability. Secondary data that provide insight are drawdowns near pumps and isotope-groundwater ages (million-year-old groundwaters in Egypt). The resultant strong simply structured three-dimensional model representation captures the essence of NAS regional groundwater-flow behavior. Model forecasts inform resource management that transboundary drawdown will likely be minimal—a nonissue—whereas drawdown within pumping centers may become excessive, requiring alternative extraction schemes; correspondingly, significant water-table drawdown may occur in pumping centers co-located with oases, causing oasis loss and environmental impacts.

The transboundary non-renewable Nubian Aquifer System of Chad, Egypt, Libya and Sudan: classical groundwater questions and parsimonious hydrogeologic analysis and modeling

NASA Astrophysics Data System (ADS)

Voss, Clifford I.; Soliman, Safaa M.

2014-03-01

Parsimonious groundwater modeling provides insight into hydrogeologic functioning of the Nubian Aquifer System (NAS), the world's largest non-renewable groundwater system (belonging to Chad, Egypt, Libya, and Sudan). Classical groundwater-resource issues exist (magnitude and lateral extent of drawdown near pumping centers) with joint international management questions regarding transboundary drawdown. Much of NAS is thick, containing a large volume of high-quality groundwater, but receives insignificant recharge, so water-resource availability is time-limited. Informative aquifer data are lacking regarding large-scale response, providing only local-scale information near pumps. Proxy data provide primary underpinning for understanding regional response: Holocene water-table decline from the previous pluvial period, after thousands of years, results in current oasis/sabkha locations where the water table still intersects the ground. Depletion is found to be controlled by two regional parameters, hydraulic diffusivity and vertical anisotropy of permeability. Secondary data that provide insight are drawdowns near pumps and isotope-groundwater ages (million-year-old groundwaters in Egypt). The resultant strong simply structured three-dimensional model representation captures the essence of NAS regional groundwater-flow behavior. Model forecasts inform resource management that transboundary drawdown will likely be minimal—a nonissue—whereas drawdown within pumping centers may become excessive, requiring alternative extraction schemes; correspondingly, significant water-table drawdown may occur in pumping centers co-located with oases, causing oasis loss and environmental impacts.

Some Studies in Large-Scale Surface Fluxes and Vertical Motions Associated with Land falling Hurricane Katrina over the Gulf of Mexico

NASA Astrophysics Data System (ADS)

Reddy, S. R.

2010-12-01

We investigated the possible relationship between the large- scale heat fluxes and intensity change associated with the landfall of Hurricane Katrina. After reaching the category 5 intensity on August 28th , 2005 over the central Gulf of Mexico, Katrina weekend to category 3 before making landfall (August 29th , 2005) on the Louisiana coast with the maximum sustained winds of over 110 knots. We also examined the vertical motions associated with the intensity change of the hurricane. The data on Convective Available Potential Energy (CAPE), sea level pressure and wind speed were obtained from the Atmospheric Soundings, and NOAA National Hurricane Center (NHC), respectively for the period August 24 to September 3, 2005. We developed an empirical model and a C++ program to calculate surface potential temperatures and heat fluxes using the above data. We also computed vertical motions using CAPE values. The study showed that the large-scale heat fluxes reached maximum (7960W/m2) with the central pressure 905mb. The Convective Available Potential Energy and the vertical motions peaked 3-5 days before landfall. The large atmospheric vertical motions associated with the land falling hurricane Katrina produced severe weather including thunderstorms and tornadoes.

The influence of the Atlantic Warm Pool on the Florida panhandle sea breeze

USGS Publications Warehouse

Misra, Vasubandhu; Moeller, Lauren; Stefanova, Lydia; Chan, Steven; O'Brien, James J.; Smith, Thomas J.; Plant, Nathaniel

2011-01-01

In this paper we examine the variations of the boreal summer season sea breeze circulation along the Florida panhandle coast from relatively high resolution (10 km) regional climate model integrations. The 23 year climatology (1979–2001) of the multidecadal dynamically downscaled simulations forced by the National Centers for Environmental Prediction–Department of Energy (NCEP-DOE) Reanalysis II at the lateral boundaries verify quite well with the observed climatology. The variations at diurnal and interannual time scales are also well simulated with respect to the observations. We show from composite analyses made from these downscaled simulations that sea breezes in northwestern Florida are associated with changes in the size of the Atlantic Warm Pool (AWP) on interannual time scales. In large AWP years when the North Atlantic Subtropical High becomes weaker and moves further eastward relative to the small AWP years, a large part of the southeast U.S. including Florida comes under the influence of relatively strong anomalous low-level northerly flow and large-scale subsidence consistent with the theory of the Sverdrup balance. This tends to suppress the diurnal convection over the Florida panhandle coast in large AWP years. This study is also an illustration of the benefit of dynamic downscaling in understanding the low-frequency variations of the sea breeze.

Modeling the Hydrologic Effects of Large-Scale Green Infrastructure Projects with GIS

NASA Astrophysics Data System (ADS)

Bado, R. A.; Fekete, B. M.; Khanbilvardi, R.

2015-12-01

Impervious surfaces in urban areas generate excess runoff, which in turn causes flooding, combined sewer overflows, and degradation of adjacent surface waters. Municipal environmental protection agencies have shown a growing interest in mitigating these effects with 'green' infrastructure practices that partially restore the perviousness and water holding capacity of urban centers. Assessment of the performance of current and future green infrastructure projects is hindered by the lack of adequate hydrological modeling tools; conventional techniques fail to account for the complex flow pathways of urban environments, and detailed analyses are difficult to prepare for the very large domains in which green infrastructure projects are implemented. Currently, no standard toolset exists that can rapidly and conveniently predict runoff, consequent inundations, and sewer overflows at a city-wide scale. We demonstrate how streamlined modeling techniques can be used with open-source GIS software to efficiently model runoff in large urban catchments. Hydraulic parameters and flow paths through city blocks, roadways, and sewer drains are automatically generated from GIS layers, and ultimately urban flow simulations can be executed for a variety of rainfall conditions. With this methodology, users can understand the implications of large-scale land use changes and green/gray storm water retention systems on hydraulic loading, peak flow rates, and runoff volumes.

Full-scale flammability test data for validation of aircraft fire mathematical models

NASA Technical Reports Server (NTRS)

Kuminecz, J. F.; Bricker, R. W.

1982-01-01

Twenty-five large scale aircraft flammability tests were conducted in a Boeing 737 fuselage at the NASA Johnson Space Center (JSC). The objective of this test program was to provide a data base on the propagation of large scale aircraft fires to support the validation of aircraft fire mathematical models. Variables in the test program included cabin volume, amount of fuel, fuel pan area, fire location, airflow rate, and cabin materials. A number of tests were conducted with jet A-1 fuel only, while others were conducted with various Boeing 747 type cabin materials. These included urethane foam seats, passenger service units, stowage bins, and wall and ceiling panels. Two tests were also included using special urethane foam and polyimide foam seats. Tests were conducted with each cabin material individually, with various combinations of these materials, and finally, with all materials in the cabin. The data include information obtained from approximately 160 locations inside the fuselage.

International Halley Watch: Discipline specialists for large scale phenomena

NASA Technical Reports Server (NTRS)

Brandt, J. C.; Niedner, M. B., Jr.

1986-01-01

The largest scale structures of comets, their tails, are extremely interesting from a physical point of view, and some of their properties are among the most spectacular displayed by comets. Because the tail(s) is an important component part of a comet, the Large-Scale Phenomena (L-SP) Discipline was created as one of eight different observational methods in which Halley data would be encouraged and collected from all around the world under the aspices of the International Halley Watch (IHW). The L-SP Discipline Specialist (DS) Team resides at NASA/Goddard Space Flight Center under the leadership of John C. Brandt, Malcolm B. Niedner, and their team of image-processing and computer specialists; Jurgan Rahe at NASA Headquarters completes the formal DS science staff. The team has adopted the study of disconnection events (DE) as its principal science target, and it is because of the rapid changes which occur in connection with DE's that such extensive global coverage was deemed necessary to assemble a complete record.

Spin-Tunnel Investigation of a 1/20-Scale Model of the Northrop F-5E Airplane

NASA Technical Reports Server (NTRS)

Scher, Stanley H.; White, William L.

1977-01-01

An investigation has been conducted in the Langley spin tunnel to determine the spin and recovery characteristics of a 1/20-scale model of the Northrop F-5E airplane. The investigation included erect and inverted spins, a range of center-of- gravity locations and moments of inertia, symmetric and asymmetric store loadings, and a determination of the parachute size required for emergency spin recovery. The effects of increased elevator trailing-edge-up deflections, of leading-edge and trailing-edge flap deflections, and of simulating the geometry of large external stores were also determined.

The Field Assessment Stroke Triage for Emergency Destination (FAST-ED): a Simple and Accurate Pre-Hospital Scale to Detect Large Vessel Occlusion Strokes

PubMed Central

Lima, Fabricio O.; Silva, Gisele S.; Furie, Karen L.; Frankel, Michael R.; Lev, Michael H.; Camargo, Érica CS; Haussen, Diogo C.; Singhal, Aneesh B.; Koroshetz, Walter J.; Smith, Wade S.; Nogueira, Raul G.

2016-01-01

Background and Purpose Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. Methods The FAST-ED scale was based on items of the NIHSS with higher predictive value for LVOS and tested in the STOPStroke cohort, in which patients underwent CT angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial-ICA, MCA-M1, MCA-2, or basilar arteries. Patients with partial, bi-hemispheric, and/or anterior + posterior circulation occlusions were excluded. Receiver operating characteristic (ROC) curve, sensitivity, specificity, positive (PPV) and negative predictive values (NPV) of FAST-ED were compared with the NIHSS, Rapid Arterial oCclusion Evaluation (RACE) scale and Cincinnati Prehospital Stroke Severity Scale (CPSSS). Results LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the ROC curve: FAST-ED=0.81 as reference; NIHSS=0.80, p=0.28; RACE=0.77, p=0.02; and CPSS=0.75, p=0.002). A FAST-ED ≥4 had sensitivity of 0.60, specificity 0.89, PPV 0.72, and NPV 0.82 versus RACE ≥5 of 0.55, 0.87, 0.68, 0.79 and CPSS ≥2 of 0.56, 0.85, 0.65, 0.78, respectively. Conclusions FAST-ED is a simple scale that if successfully validated in the field may be used by medical emergency professionals to identify LVOS in the pre-hospital setting enabling rapid triage of patients. PMID:27364531

Using First Differences to Reduce Inhomogeneity in Radiosonde Temperature Datasets.

NASA Astrophysics Data System (ADS)

Free, Melissa; Angell, James K.; Durre, Imke; Lanzante, John; Peterson, Thomas C.; Seidel, Dian J.

2004-11-01

The utility of a “first difference” method for producing temporally homogeneous large-scale mean time series is assessed. Starting with monthly averages, the method involves dropping data around the time of suspected discontinuities and then calculating differences in temperature from one year to the next, resulting in a time series of year-to-year differences for each month at each station. These first difference time series are then combined to form large-scale means, and mean temperature time series are constructed from the first difference series. When applied to radiosonde temperature data, the method introduces random errors that decrease with the number of station time series used to create the large-scale time series and increase with the number of temporal gaps in the station time series. Root-mean-square errors for annual means of datasets produced with this method using over 500 stations are estimated at no more than 0.03 K, with errors in trends less than 0.02 K decade-1 for 1960 97 at 500 mb. For a 50-station dataset, errors in trends in annual global means introduced by the first differencing procedure may be as large as 0.06 K decade-1 (for six breaks per series), which is greater than the standard error of the trend. Although the first difference method offers significant resource and labor advantages over methods that attempt to adjust the data, it introduces an error in large-scale mean time series that may be unacceptable in some cases.

Description of a Compensatory College Education Program for the Disadvantaged and Its Associated Research and Evaluation Program.

ERIC Educational Resources Information Center

Spuck, Dennis W.; And Others

This paper reports on a large-scale project of research and evaluation of a program for disadvantaged minority group students conducted by the Center for Educational Opportunity at the Claremont Colleges. The Program of Special Directed Studies for Transition to College (PSDS), a five-year experimental project, is aimed at providing a four-year,…

Applications for Micrographics in Large Scale Information Systems of the Future. Volume II: Part III. A Review of Micrographics State-of-the-Art.

ERIC Educational Resources Information Center

Information Dynamics Corp., Reading, MA.

A five-year development program plan was drawn up for the Defense Documentation Center (DDC). This report presents in summary form the results of various surveys and reviews performed in selected areas of micrographics to support the efforts of the program's planners. Exhibits of supporting documentation are presented, together with a discussion…

Methodological Issues in the Study of Teachers' Careers: Critical Features of a Truly Longitudinal Study. Working Paper Series.

ERIC Educational Resources Information Center

Singer, Judith D.; Willett, John B.

The National Center for Education Statistics (NCES) is exploring the possibility of conducting a large-scale multi-year study of teachers' careers. The proposed new study is intended to follow a national probability sample of teachers over an extended period of time. A number of methodological issues need to be addressed before the study can be…

A new FIA-Type strategic inventory (NFI)

Treesearch

Richard A. Grotefendt; Hans T. Schreuder

2006-01-01

New remote sensing technologies are now available to lower the cost of doing strategic surveys. A new sampling approach for the Forest Inventory and Analysis program (FIA) of the U.S.D.A. Forest Service is discussed involving a bi-sampling unit (BSU) that is composed of a field sample unit (FSU) centered within a large scale (1:1,000 to 1:3,000) photo sample unit (PSU...

Characteristics of At-Risk Students in NELS:88. National Education Longitudinal Study of 1988. Statistical Analysis Report. Contractor Report. NCES 92-042

ERIC Educational Resources Information Center

Kaufman, Phillip; Bradbury, Denise

1992-01-01

The National Education Longitudinal Study of 1988 (NELS:88) is a large-scale, national longitudinal study designed and sponsored by the National Center for Education Statistics (NCES), with support from other government agencies. Beginning in the spring of 1988 with a cohort of eighth graders (25,000) attending public and private schools across…

Large-Scale Physical Separation of Depleted Uranium from Soil

DTIC Science & Technology

2012-09-01

Earth and Environment 285 Davidson Avenue, Suite 100 Somerset, NJ 08873 Catherine Nestler Applied Research Associates, Inc. 119 Monument Place...square meters square miles 2.589998 E+06 square meters square yards 0.8361274 square meters yards 0.9144 meters ERDC/EL TR-12-25 viii...depleted uranium EL Environmental Laboratory ERDC Engineer Research and Development Center ICP-MS Inductively coupled plasma - mass spectroscopy

Vaccine manufacturing and technology: from biotechnological platforms to syntethic epitopes, current viepoint.

PubMed

Ignateva, G A

2016-01-01

The Purposes: the review take into account short history of vaccination practice and development of vaccine technology. In the review we include data from several monographs about manufacturing of vaccines published by authors from such companies as Merck & Co; Sanofi Pasteur; Dynavax Europe/Rhein Biotech GmbH; Latham Biopharm Group; Aridis Pharmaceuticals LLC; Genentech; Amgen; Shamir Biologics LLC; Biopharm Services US; Novartis Pharma AG, аnd several research centers: Laboratory of Bacterial Polysaccharides, Center for Biologics Evaluation and Research; Purdue University, West Lafayette, IN, US; Department of Pharmaceutical Chemistry, Univ. Of Kansas; Max Planck Institute for dynamics of Complex Technical Systems; Fraunhofer USA Center for Molecular Biotechnology; US Dep. of Agriculture Animal and Plant Health Inspection Service, etc. In historic literature there are data about inoculation practices in antique China, Persia, India, Byzantium, native Americans, some African population. In modern immunology since the end of XIX century the vaccines were produced at the in vivo platforms - in animals (rabbits, mice, cows). Since 1931 due to E. Goodpasture' elaboration most virus vaccines were and are produced at the in ovo platform. In 1949 J.F. Enders elaborated large-scale polio virus production in the primary culture of monkey kidney cells in vitro. Up to day primary culture of chiken embrio fibroblasts are used to large-scale production of vaccine viruses of measles, mumps, rabies. Since 2000-th in Western countries most part of virus vaccines were began to produced via a cultivation in continuous tumor cell lines. The last technology is the most low cost for large-scale production of vaccines. We review several new biotechnological platforms for the production of the recombinant protein or virus-like particles as subunit vaccines: plant system, algae, mushrooms, insect cells, etc. Beside of good purpose of vaccination - prophylactic of several infectious deseases, doctors must take into account possibility of inter-species transmission of unknown pathogens (retroviruses, prions, etc) from biotechnological platforms - animals, cell cultures - into human population, and don't ignore L.A. Zilber' theory of virus' etiology of cancer diseases.

The circumstellar disk response to the motion of the host star

NASA Astrophysics Data System (ADS)

Regály, Zs.; Vorobyov, E.

2017-05-01

Context. Grid-based hydrodynamics simulations of circumstellar disks are often performed in the curvilinear coordinate system, in which the center of the computational domain coincides with the motionless star. However, the center of mass may be shifted from the star due to the presence of any non-axisymmetric mass distribution. As a result, the system exerts a non-zero gravity force on the star, causing the star to move in response, which can in turn affect the evolution of the circumstellar disk. Aims: We aim at studying the effects of stellar motion on the evolution of protostellar and protoplanetary disks. In protostellar disks, a non-axisymmetric distribution of matter in the form of spiral arms and/or massive clumps can form due to gravitational instability. Protoplanetary disks can also feature non-axisymmetric structures caused by an embedded high-mass planet or a large-scale vortex formed at viscosity transitions. Methods: We use 2D grid-based numerical hydrodynamic simulations to explore the effect of stellar motion. We adopt a non-inertial polar coordinate system centered on the star, in which the stellar motion is taken into account by calculating the indirect potential caused by the non-axisymmetric disk, a high-mass planet, or a large-scale vortex. We compare the results of numerical simulations with and without stellar motion. Results: We found that the stellar motion has a moderate effect on the evolution history and the mass accretion rate in protostellar disks, reducing somewhat the disk size and mass, while having a profound effect on the collapsing envelope, changing its inner shape from an initially axisymmetric to a non-axisymmetric configuration. Protoplanetary disk simulations show that the stellar motion slightly reduces the width of the gap opened by a high-mass planet, decreases the planet migration rate, and strengthens the large-scale vortices formed at the viscosity transition. Conclusions: We conclude that the inclusion of the indirect potential is recommended in grid-based hydrodynamics simulations of circumstellar disks which use the curvilinear coordinate system.

A Continental-scale River Corridor Model to Synthesize Understanding and Prioritize Management of Water Purification Functions and Ecological Services in Large Basins

NASA Astrophysics Data System (ADS)

Harvey, J. W.; Gomez-Velez, J. D.; Scott, D.; Boyer, E. W.; Schmadel, N. M.; Alexander, R. B.; Eng, K.; Golden, H. E.; Kettner, A.; Konrad, C. P.; Moore, R. B.; Pizzuto, J. E.; Schwarz, G. E.; Soulsby, C.

2017-12-01

The functional values of rivers depend on more than just wetted river channels. Instead, the river channel exchanges water and suspended materials with adjacent riparian, floodplain, hyporheic zones, and ponded waters such as lakes and reservoirs. Together these features comprise a larger functional unit known as the river corridor. The exchange of water, solutes, and sediments within the river corridor alters downstream water quality and ecological functions, but our understanding of the large-scale, cumulative impacts is inadequate and has limited advancements in sustainable management practices. A problem with traditional watershed, groundwater, and river water quality models is that none of them explicitly accounts for river corridor storage and processing, and the exchanges of water, solutes, and sediments that occur many times between the channel and off-channel environments during a river's transport to the sea. Our River Corridor Working Group at the John Wesley Powell Center is quantifying the key components of river corridor functions. Relying on foundational studies that identified floodplain, riparian, and hyporheic exchange flows and resulting enhancement of chemical reactions at river reach scales, we are assembling the datasets and building the models to upscale that understanding onto 2.6 million river reaches in the U.S. A principal goal of the River Corridor Working group is to develop a national-scale river corridor model for the conterminous U.S. that will reveal, perhaps for the first time, the relative influences of hyporheic, riparian, floodplain, and ponded waters at large spatial scales. The simple but physically-based models are predictive for changing conditions and therefore can directly address the consequences and effectiveness of management actions in sustaining valuable river corridor functions. This presentation features interpretation of useful river corridor connectivity metrics and ponded water influences on nutrient and sediment processing in river networks of the Mid-Atlantic and Northeastern U.S. This research is a product of the John Wesley Powell Center River Corridor Working Group https://powellcenter.usgs.gov/view-project

A Green Bank Telescope 21cm survey of HI clouds in the Milky Way's nuclear wind

NASA Astrophysics Data System (ADS)

Denbo, Sara; Endsley, Ryan; Lockman, Felix J.; Ford, Alyson

2015-01-01

Feedback processes such as large-scale galactic winds are thought to be responsible for distributing enriched gas throughout a galaxy and even into the IGM. Such winds have been found in many galaxies with active star formation near their center, and the Fermi bubbles provide evidence for such a nuclear wind in our own Milky Way. A recent 21 cm HI survey by the Australia Telescope Compact Array discovered a population of compact, isolated clouds surrounding the Galactic Center that may be entrained in the Fermi bubble wind. We present data from a survey of 21cm HI over an extended region around the Galactic Center using the Green Bank Telescope. These observations provide more strict constraints on neutral clouds in the Fermi bubble wind, and a more robust description of the parameters of HI clouds (i.e., mass, column density, and lifetime) near the Galactic Center.

Physics of the 1 Teraflop RIKEN-BNL-Columbia QCD project. Proceedings of RIKEN BNL Research Center workshop: Volume 13

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-10-16

A workshop was held at the RIKEN-BNL Research Center on October 16, 1998, as part of the first anniversary celebration for the center. This meeting brought together the physicists from RIKEN-BNL, BNL and Columbia who are using the QCDSP (Quantum Chromodynamics on Digital Signal Processors) computer at the RIKEN-BNL Research Center for studies of QCD. Many of the talks in the workshop were devoted to domain wall fermions, a discretization of the continuum description of fermions which preserves the global symmetries of the continuum, even at finite lattice spacing. This formulation has been the subject of analytic investigation for somemore » time and has reached the stage where large-scale simulations in QCD seem very promising. With the computational power available from the QCDSP computers, scientists are looking forward to an exciting time for numerical simulations of QCD.« less

Compression Buckling Behavior of Large-Scale Friction Stir Welded and Riveted 2090-T83 Al-Li Alloy Skin-Stiffener Panels

NASA Technical Reports Server (NTRS)

Hoffman, Eric K.; Hafley, Robert A.; Wagner, John A.; Jegley, Dawn C.; Pecquet, Robert W.; Blum, Celia M.; Arbegast, William J.

2002-01-01

To evaluate the potential of friction stir welding (FSW) as a replacement for traditional rivet fastening for launch vehicle dry bay construction, a large-scale friction stir welded 2090-T83 aluminum-lithium (Al-Li) alloy skin-stiffener panel was designed and fabricated by Lockheed-Martin Space Systems Company - Michoud Operations (LMSS) as part of NASA Space Act Agreement (SAA) 446. The friction stir welded panel and a conventional riveted panel were tested to failure in compression at the NASA Langley Research Center (LaRC). The present paper describes the compression test results, stress analysis, and associated failure behavior of these panels. The test results provide useful data to support future optimization of FSW processes and structural design configurations for launch vehicle dry bay structures.

A Two-Stage Approach for Medical Supplies Intermodal Transportation in Large-Scale Disaster Responses

PubMed Central

Ruan, Junhu; Wang, Xuping; Shi, Yan

2014-01-01

We present a two-stage approach for the “helicopters and vehicles” intermodal transportation of medical supplies in large-scale disaster responses. In the first stage, a fuzzy-based method and its heuristic algorithm are developed to select the locations of temporary distribution centers (TDCs) and assign medial aid points (MAPs) to each TDC. In the second stage, an integer-programming model is developed to determine the delivery routes. Numerical experiments verified the effectiveness of the approach, and observed several findings: (i) More TDCs often increase the efficiency and utility of medical supplies; (ii) It is not definitely true that vehicles should load more and more medical supplies in emergency responses; (iii) The more contrasting the traveling speeds of helicopters and vehicles are, the more advantageous the intermodal transportation is. PMID:25350005

A streamlined collecting and preparation protocol for DNA barcoding of Lepidoptera as part of large-scale rapid biodiversity assessment projects, exemplified by the Indonesian Biodiversity Discovery and Information System (IndoBioSys).

PubMed

Schmidt, Olga; Hausmann, Axel; Cancian de Araujo, Bruno; Sutrisno, Hari; Peggie, Djunijanti; Schmidt, Stefan

2017-01-01

Here we present a general collecting and preparation protocol for DNA barcoding of Lepidoptera as part of large-scale rapid biodiversity assessment projects, and a comparison with alternative preserving and vouchering methods. About 98% of the sequenced specimens processed using the present collecting and preparation protocol yielded sequences with more than 500 base pairs. The study is based on the first outcomes of the Indonesian Biodiversity Discovery and Information System (IndoBioSys). IndoBioSys is a German-Indonesian research project that is conducted by the Museum für Naturkunde in Berlin and the Zoologische Staatssammlung München, in close cooperation with the Research Center for Biology - Indonesian Institute of Sciences (RCB-LIPI, Bogor).

Large Field Photogrammetry Techniques in Aircraft and Spacecraft Impact Testing

NASA Technical Reports Server (NTRS)

Littell, Justin D.

2010-01-01

The Landing and Impact Research Facility (LandIR) at NASA Langley Research Center is a 240 ft. high A-frame structure which is used for full-scale crash testing of aircraft and rotorcraft vehicles. Because the LandIR provides a unique capability to introduce impact velocities in the forward and vertical directions, it is also serving as the facility for landing tests on full-scale and sub-scale Orion spacecraft mass simulators. Recently, a three-dimensional photogrammetry system was acquired to assist with the gathering of vehicle flight data before, throughout and after the impact. This data provides the basis for the post-test analysis and data reduction. Experimental setups for pendulum swing tests on vehicles having both forward and vertical velocities can extend to 50 x 50 x 50 foot cubes, while weather, vehicle geometry, and other constraints make each experimental setup unique to each test. This paper will discuss the specific calibration techniques for large fields of views, camera and lens selection, data processing, as well as best practice techniques learned from using the large field of view photogrammetry on a multitude of crash and landing test scenarios unique to the LandIR.

Aeroelastic Stability Investigations for Large-scale Vertical Axis Wind Turbines

NASA Astrophysics Data System (ADS)

Owens, B. C.; Griffith, D. T.

2014-06-01

The availability of offshore wind resources in coastal regions, along with a high concentration of load centers in these areas, makes offshore wind energy an attractive opportunity for clean renewable electricity production. High infrastructure costs such as the offshore support structure and operation and maintenance costs for offshore wind technology, however, are significant obstacles that need to be overcome to make offshore wind a more cost-effective option. A vertical-axis wind turbine (VAWT) rotor configuration offers a potential transformative technology solution that significantly lowers cost of energy for offshore wind due to its inherent advantages for the offshore market. However, several potential challenges exist for VAWTs and this paper addresses one of them with an initial investigation of dynamic aeroelastic stability for large-scale, multi-megawatt VAWTs. The aeroelastic formulation and solution method from the BLade Aeroelastic STability Tool (BLAST) for HAWT blades was employed to extend the analysis capability of a newly developed structural dynamics design tool for VAWTs. This investigation considers the effect of configuration geometry, material system choice, and number of blades on the aeroelastic stability of a VAWT, and provides an initial scoping for potential aeroelastic instabilities in large-scale VAWT designs.

Application of Dynamic Mode Decomposition: Temporal Evolution of Flow Structures in an Aneurysm

NASA Astrophysics Data System (ADS)

Conlin, William; Yu, Paulo; Durgesh, Vibhav

2017-11-01

An aneurysm is an enlargement of a weakened arterial wall that can be fatal or debilitating on rupture. Aneurysm hemodynamics is integral to developing an understanding of aneurysm formation, growth, and rupture. The flow in an aneurysm exhibits complex fluid dynamics behavior due to an inherent unsteady inflow condition and its interactions with large-scale flow structures present in the aneurysm. The objective of this study is to identify the large-scale structures in the aneurysm, study temporal behavior, and quantify their interaction with the inflow condition. For this purpose, detailed Particle Image Velocimetry (PIV) measurements were performed at the center plane of an idealized aneurysm model for a range of inflow conditions. Inflow conditions were precisely controlled using a ViVitro SuperPump system. Dynamic Modal Decomposition (DMD) of the velocity field was used to identify coherent structures and their temporal behavior. DMD was successful in capturing the large-scale flow structures and their temporal behavior. A low dimensional approximation to the flow field was obtained with the most relevant dynamic modes and was used to obtain temporal information about the coherent structures and their interaction with the inflow, formation, evolution, and growth.

Applying the 15 Public Health Emergency Preparedness Capabilities to Support Large-Scale Tuberculosis Investigations in Complex Congregate Settings

PubMed Central

Toren, Katelynne Gardner; Elsenboss, Carina; Narita, Masahiro

2017-01-01

Public Health—Seattle and King County, a metropolitan health department in western Washington, experiences rates of tuberculosis (TB) that are 1.6 times higher than are state and national averages. The department’s TB Control Program uses public health emergency management tools and capabilities sustained with Centers for Disease Control and Prevention grant funding to manage large-scale complex case investigations. We have described 3 contact investigations in large congregate settings that the TB Control Program conducted in 2015 and 2016. The program managed the investigations using public health emergency management tools, with support from the Preparedness Program. The 3 investigations encompassed medical evaluation of more than 1600 people, used more than 100 workers, identified nearly 30 individuals with latent TB infection, and prevented an estimated 3 cases of active disease. These incidents exemplify how investments in public health emergency preparedness can enhance health outcomes in traditional areas of public health. PMID:28892445

Zebrafish Health Conditions in the China Zebrafish Resource Center and 20 Major Chinese Zebrafish Laboratories.

PubMed

Liu, Liyue; Pan, Luyuan; Li, Kuoyu; Zhang, Yun; Zhu, Zuoyan; Sun, Yonghua

2016-07-01

In China, the use of zebrafish as an experimental animal in the past 15 years has widely expanded. The China Zebrafish Resource Center (CZRC), which was established in 2012, is becoming one of the major resource centers in the global zebrafish community. Large-scale use and regular exchange of zebrafish resources have put forward higher requirements on zebrafish health issues in China. This article reports the current aquatic infrastructure design, animal husbandry, and health-monitoring programs in the CZRC. Meanwhile, through a survey of 20 Chinese zebrafish laboratories, we also describe the current health status of major zebrafish facilities in China. We conclude that it is of great importance to establish a widely accepted health standard and health-monitoring strategy in the Chinese zebrafish research community.

Expectancy violation in physics and mathematics classes in a student-centered classroom

NASA Astrophysics Data System (ADS)

Alvarado, Carolina; Dominguez, Angeles; Rodriguez, Ruth; Zavala, Genaro

2012-02-01

This report analyzes the results of the implementation at a large private Mexican university of the Pedagogical Expectancy Violation Assessment (PEVA), developed by Gaffney, Gaffney and Beichner [1]. The PEVA was designed to evaluate shifts of the first student's expectations due to the initial orientation and experiences in the classroom. The data was collected at the Student-Centered Learning (ACE) classroom, based on the Student Centered Active Learning Environment for Undergraduate Programs (SCALE-UP) classroom. Three professors participated with their groups during the first semester they implemented their courses in this environment. Participants were enrolled either in a Pre-Calculus, Differential Equations, or Electricity and Magnetism course. The results indicate shifts in students' expectations during the semester and reveals differences in shifts among the different courses.

Atla Regio, Venus: Geology and origin of a major equatorial volcanic rise

NASA Technical Reports Server (NTRS)

Senske, D. A.; Head, James W., III

1992-01-01

Regional volcanic rises form a major part of the highlands in the equatorial region of Venus. These broad domical uplands, 1000 to 3000 km across, contain centers of volcanism forming large edifices and are associated with extension and rifting. Two classes of rises are observed: (1) those that are dominated by tectonism, acting as major centers for converging rifts such as Beta Regio and Alta Regio, and are termed tectonic junctions; and (2) those forming uplands characterized primarily by large-scale volcanism forming edifices. Western Eistla Regio and Bell Regio, where zones of extension and rifting are less developed. Within this second class of features the edifices are typically found at the end of a single rift, or are associated with a linear belt of deformation. We examine the geologic characteristics of the tectonic junction at Alta Regio, concentrating on documenting the styles of volcanism and assessing mechanisms for the formation of regional topography.

Launch processing system transition from development to operation

NASA Technical Reports Server (NTRS)

Paul, H. C.

1977-01-01

The Launch Processing System has been under development at Kennedy Space Center since 1973. A prototype system was developed and delivered to Marshall Space Flight Center for Solid Rocket Booster checkout in July 1976. The first production hardware arrived in late 1976. The System uses a distributed computer network for command and monitoring and is supported by a dual large scale computer system for 'off line' processing. A high level of automation is anticipated for Shuttle and Payload testing and launch operations to gain the advantages of short turnaround capability, repeatability of operations, and minimization of operations and maintenance (O&M) manpower. Learning how to efficiently apply the system is our current problem. We are searching for more effective ways to convey LPS system performance characteristics from the designer to a large number of users. Once we have done this, we can realize the advantages of LPS system design.

Modernization of the graphics post-processors of the Hamburg German Climate Computer Center Carbon Cycle Codes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stevens, E.J.; McNeilly, G.S.

The existing National Center for Atmospheric Research (NCAR) code in the Hamburg Oceanic Carbon Cycle Circulation Model and the Hamburg Large-Scale Geostrophic Ocean General Circulation Model was modernized and reduced in size while still producing an equivalent end result. A reduction in the size of the existing code from more than 50,000 lines to approximately 7,500 lines in the new code has made the new code much easier to maintain. The existing code in Hamburg model uses legacy NCAR (including even emulated CALCOMP subrountines) graphics to display graphical output. The new code uses only current (version 3.1) NCAR subrountines.

SANs and Large Scale Data Migration at the NASA Center for Computational Sciences

NASA Technical Reports Server (NTRS)

Salmon, Ellen M.

2004-01-01

Evolution and migration are a way of life for provisioners of high-performance mass storage systems that serve high-end computers used by climate and Earth and space science researchers: the compute engines come and go, but the data remains. At the NASA Center for Computational Sciences (NCCS), disk and tape SANs are deployed to provide high-speed I/O for the compute engines and the hierarchical storage management systems. Along with gigabit Ethernet, they also enable the NCCS's latest significant migration: the transparent transfer of 300 Til3 of legacy HSM data into the new Sun SAM-QFS cluster.

Dark Energy Domination In The Virgocentric Flow

NASA Astrophysics Data System (ADS)

Byrd, Gene; Chernin, A. D.; Karachentsev, I. D.; Teerikorpi, P.; Valtonen, M.; Dolgachev, V. P.; Domozhilova, L. M.

2011-04-01

Dark energy (DE) was first observationally detected at large Gpc distances. If it is a vacuum energy formulated as Einstein's cosmological constant, Λ, DE should also have dynamical effects at much smaller scales. Previously, we found its effects on much smaller Mpc scales in our Local Group (LG) as well as in other nearby groups. We used new HST observations of member 3D distances from the group centers and Doppler shifts. We find each group's gravity dominates a bound central system of galaxies but DE antigravity results in a radial recession increasing with distance from the group center of the outer members. Here we focus on the much larger (but still cosmologically local) Virgo Cluster and systems around it using new observations of velocities and distances. We propose an analytic model whose key parameter is the zero-gravity radius (ZGR) from the cluster center where gravity and DE antigravity balance. DE brings regularity to the Virgocentric flow. Beyond Virgo's 10 Mpc ZGR, the flow curves to approach a linear global Hubble law at larger distances. The Virgo cluster and its outer flow are similar to the Local Group and its local outflow with a scaling factor of about 10; the ZGR for Virgo is 10 times larger than that of the LG. The similarity of the two systems on the scales of 1 to 30 Mpc suggests that a quasi-stationary bound central component and an expanding outflow applies to a wide range of groups and clusters due to small scale action of DE as well as gravity. Chernin, et al 2009 Astronomy and Astrophysics 507, 1271 http://arxiv.org/abs/1006.0066 http://arxiv.org/abs/1006.0555

LOLA Project Artists

NASA Image and Video Library

1965-08-10

Artists used paintbrushes and airbrushes to recreate the lunar surface on each of the four models comprising the LOLA simulator. Project LOLA or Lunar Orbit and Landing Approach was a simulator built at Langley to study problems related to landing on the lunar surface. It was a complex project that cost nearly 2 million dollars. James Hansen wrote: This simulator was designed to provide a pilot with a detailed visual encounter with the lunar surface the machine consisted primarily of a cockpit, a closed-circuit TV system, and four large murals or scale models representing portions of the lunar surface as seen from various altitudes. The pilot in the cockpit moved along a track past these murals which would accustom him to the visual cues for controlling a spacecraft in the vicinity of the moon. Unfortunately, such a simulation--although great fun and quite aesthetic--was not helpful because flight in lunar orbit posed no special problems other than the rendezvous with the LEM, which the device did not simulate. Not long after the end of Apollo, the expensive machine was dismantled. (p. 379) Ellis J. White described the simulator as follows: Model 1 is a 20-foot-diameter sphere mounted on a rotating base and is scaled 1 in. 9 miles. Models 2,3, and 4 are approximately 15x40 feet scaled sections of model 1. Model 4 is a scaled-up section of the Crater Alphonsus and the scale is 1 in. 200 feet. All models are in full relief except the sphere. -- Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From Sputnik to Apollo, (Washington: NASA, 1995), p. 379 Ellis J. White, Discussion of Three Typical Langley Research Center Simulation Programs, Paper presented at the Eastern Simulation Council (EAI s Princeton Computation Center), Princeton, NJ, October 20, 1966.

LOLA Project

NASA Image and Video Library

1964-10-28

Artists used paintbrushes and airbrushes to recreate the lunar surface on each of the four models comprising the LOLA simulator. Project LOLA or Lunar Orbit and Landing Approach was a simulator built at Langley to study problems related to landing on the lunar surface. It was a complex project that cost nearly $2 million dollars. James Hansen wrote: "This simulator was designed to provide a pilot with a detailed visual encounter with the lunar surface; the machine consisted primarily of a cockpit, a closed-circuit TV system, and four large murals or scale models representing portions of the lunar surface as seen from various altitudes. The pilot in the cockpit moved along a track past these murals which would accustom him to the visual cues for controlling a spacecraft in the vicinity of the moon. Unfortunately, such a simulation--although great fun and quite aesthetic--was not helpful because flight in lunar orbit posed no special problems other than the rendezvous with the LEM, which the device did not simulate. Not long after the end of Apollo, the expensive machine was dismantled." (p. 379) Ellis J. White further described LOLA in his paper "Discussion of Three Typical Langley Research Center Simulation Programs," "Model 1 is a 20-foot-diameter sphere mounted on a rotating base and is scaled 1 in. = 9 miles. Models 2,3, and 4 are approximately 15x40 feet scaled sections of model 1. Model 4 is a scaled-up section of the Crater Alphonsus and the scale is 1 in. = 200 feet. All models are in full relief except the sphere." -- Published in James R. Hansen, Spaceflight Revolution, NASA SP-4308, p. 379; Ellis J. White, "Discussion of Three Typical Langley Research Center Simulation Programs," Paper presented at the Eastern Simulation Council (EAI's Princeton Computation Center), Princeton, NJ, October 20, 1966.

The OLI Radiometric Scale Realization Round Robin Measurement Campaign

NASA Technical Reports Server (NTRS)

Cutlip, Hansford; Cole,Jerold; Johnson, B. Carol; Maxwell, Stephen; Markham, Brian; Ong, Lawrence; Hom, Milton; Biggar, Stuart

2011-01-01

A round robin radiometric scale realization was performed at the Ball Aerospace Radiometric Calibration Laboratory in January/February 2011 in support of the Operational Land Imager (OLI) Program. Participants included Ball Aerospace, NIST, NASA Goddard Space Flight Center, and the University of Arizona. The eight day campaign included multiple observations of three integrating sphere sources by nine radiometers. The objective of the campaign was to validate the radiance calibration uncertainty ascribed to the integrating sphere used to calibrate the OLI instrument. The instrument level calibration source uncertainty was validated by quatnifying: (1) the long term stability of the NIST calibrated radiance artifact, (2) the responsivity scale of the Ball Aerospace transfer radiometer and (3) the operational characteristics of the large integrating sphere.

Dynamical Processes Near the Super Massive Black Hole at the Galactic Center

NASA Astrophysics Data System (ADS)

Antonini, Fabio

2011-01-01

Observations of the stellar environment near the Galactic center provide the strongest empirical evidence for the existence of massive black holes in the Universe. Theoretical models of the Milky Way nuclear star cluster fail to explain numerous properties of such environment, including the presence of very young stars close to the super massive black hole (SMBH) and the more recent discovery of a parsec-scale core in the central distribution of the bright late-type (old) stars. In this thesis we present a theoretical study of dynamical processes near the Galactic center, strongly related to these issues. Using different numerical techniques we explore the close environment of a SMBH as catalyst for stellar collisions and mergers. We study binary stars that remain bound for several revolutions around the SMBH, finding that in the case of highly inclined binaries the Kozai resonance can lead to large periodic oscillations in the internal binary eccentricity and inclination. Collisions and mergers of the binary elements are found to increase significantly for multiple orbits around the SMBH. In collisions involving a low-mass and a high-mass star, the merger product acquires a high core hydrogen abundance from the smaller star, effectively resetting the nuclear evolution clock to a younger age. This process could serve as an important source of young stars at the Galactic center. We then show that a core in the old stars can be naturally explained in a scenario in which the Milky Way nuclear star cluster (NSC) is formed via repeated inspiral of globular clusters into the Galactic center. We present results from a set of N -body simulations of this process, which show that the fundamental properties of the NSC, including its mass, outer density profile and velocity structure, are also reproduced. Chandrasekhar's dynamical friction formula predicts no frictional force on a test body in a low-density core, regardless of its density, due to the absence of stars moving more slowly than the local circular velocity. We have tested this prediction using large-scale N -body experiments. The rate of orbital decay never drops precisely to zero, because stars moving faster than the test body also contribute to the frictional force. When the contribution from the fast-moving stars is included in the expression for the dynamical friction force, and the changes induced by the massive body on the stellar distribution are taken into account, Chandrasekhar's theory is found to reproduce the rate of orbital decay remarkably well. However, this rate is still substantially smaller than the rate predicted by Chandrasekhar's formula in its most widely-used forms, implying longer time scales for inspiral. Motivated by recent observations that suggest a parsec-scale core around the Galactic center SMBH, we investigated the evolution of a population of stellar-mass black holes (BHs) as they spiral in to the center of the Galaxy. After ˜ 10 Gyr, we find that the density of BHs can remain substantially less than the density in stars at all radii; we conclude that it would be unjustified to assume that the spatial distribution of BHs at the Galactic center is well described by steady-state models.

Prediction of Large Vessel Occlusions in Acute Stroke: National Institute of Health Stroke Scale Is Hard to Beat.

PubMed

Vanacker, Peter; Heldner, Mirjam R; Amiguet, Michael; Faouzi, Mohamed; Cras, Patrick; Ntaios, George; Arnold, Marcel; Mattle, Heinrich P; Gralla, Jan; Fischer, Urs; Michel, Patrik

2016-06-01

Endovascular treatment for acute ischemic stroke with a large vessel occlusion was recently shown to be effective. We aimed to develop a score capable of predicting large vessel occlusion eligible for endovascular treatment in the early hospital management. Retrospective, cohort study. Two tertiary, Swiss stroke centers. Consecutive acute ischemic stroke patients (1,645 patients; Acute STroke Registry and Analysis of Lausanne registry), who had CT angiography within 6 and 12 hours of symptom onset, were categorized according to the occlusion site. Demographic and clinical information was used in logistic regression analysis to derive predictors of large vessel occlusion (defined as intracranial carotid, basilar, and M1 segment of middle cerebral artery occlusions). Based on logistic regression coefficients, an integer score was created and validated internally and externally (848 patients; Bernese Stroke Registry). None. Large vessel occlusions were present in 316 patients (21%) in the derivation and 566 (28%) in the external validation cohort. Five predictors added significantly to the score: National Institute of Health Stroke Scale at admission, hemineglect, female sex, atrial fibrillation, and no history of stroke and prestroke handicap (modified Rankin Scale score, < 2). Diagnostic accuracy in internal and external validation cohorts was excellent (area under the receiver operating characteristic curve, 0.84 both). The score performed slightly better than National Institute of Health Stroke Scale alone regarding prediction error (Wilcoxon signed rank test, p < 0.001) and regarding discriminatory power in derivation and pooled cohorts (area under the receiver operating characteristic curve, 0.81 vs 0.80; DeLong test, p = 0.02). Our score accurately predicts the presence of emergent large vessel occlusions, which are eligible for endovascular treatment. However, incorporation of additional demographic and historical information available on hospital arrival provides minimal incremental predictive value compared with the National Institute of Health Stroke Scale alone.

Determining pain scale preference in a veteran population experiencing chronic pain.

PubMed

Douglas, Mary E; Randleman, Mary L; DeLane, Alice M; Palmer, Glen A

2014-09-01

The purpose of this study was to determine veteran pain scale preference of four common pain scales: the Faces Scale, the Visual Analog Scale, the Numeric Rating Scale, and the Mankoski Pain Scale. The study also examined the reliability and validity of the Mankoski Pain Scale with the other three scales. A sample of veterans (N = 200) with chronic pain receiving treatment in a residential rehabilitation treatment program (RRTP) and a surgical and specialty care (SSC) outpatient clinic at a Department of Veterans Affairs (VA) medical center participated in the study. There was a significant difference between scales in regard to preference, χ2(3) = 64.59, p < .001. A large percentage of the sample preferred the Mankoski Pain Scale (46%). Test-retest of the reliability was comparable for all the scales. Validity of the Mankoski scale was excellent, as it correlated very well with the Numeric (r = .84, p < .001), Analog (r = .83, p < .001), and Faces (r = .78, p < .001) scales. The findings indicate that the Mankoski Pain Scale is a valid and reliable tool for pain with veterans, and it was the preferred scale by veterans for use when describing pain. Published by Elsevier Inc.

Visualizing the Big (and Large) Data from an HPC Resource

NASA Astrophysics Data System (ADS)

Sisneros, R.

2015-10-01

Supercomputers are built to endure painfully large simulations and contend with resulting outputs. These are characteristics that scientists are all too willing to test the limits of in their quest for science at scale. The data generated during a scientist's workflow through an HPC center (large data) is the primary target for analysis and visualization. However, the hardware itself is also capable of generating volumes of diagnostic data (big data); this presents compelling opportunities to deploy analogous analytic techniques. In this paper we will provide a survey of some of the many ways in which visualization and analysis may be crammed into the scientific workflow as well as utilized on machine-specific data.

Characterization of Mineralogy Across Vesta

NASA Technical Reports Server (NTRS)

De Sanctis, M. C.; Ammannito, E.; Capria, M. T.; Capaccioni, F.; Carraro, F.; Fonte, S.; Frigeri, A.; Magni, G.; Marchi, S.; Palomba, E.;

Dislocation Multiplication by Single Cross Slip for FCC at Submicron Scales

NASA Astrophysics Data System (ADS)

Cui, Yi-Nan; Liu, Zhan-Li; Zhuang, Zhuo

2013-04-01

The operation mechanism of single cross slip multiplication (SCSM) is investigated by studying the response of one dislocation loop expanding in face-centered-cubic (FCC) single crystal using three-dimensional discrete dislocation dynamic (3D-DDD) simulation. The results show that SCSM can trigger highly correlated dislocation generation in a short time, which may shed some light on understanding the large strain burst observed experimentally. Furthermore, we find that there is a critical stress and material size for the operation of SCSM, which agrees with that required to trigger large strain burst in the compression tests of FCC micropillars.

KSC-2011-8245

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida negotiates the turn from Kennedy Parkway onto Schwartz Road on its way toward NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8243

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida moves past the traffic signals onto Kennedy Parkway as it travels northbound toward NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8236

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida nears the intersection of NASA Causeway and Kennedy Parkway. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8228

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – A transporter carrying the high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida rolls along the NASA Causeway as it leaves the visitor complex on its way to NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

Development and psychometric characteristics of the SCI-QOL Pressure Ulcers scale and short form

PubMed Central

Kisala, Pamela A.; Tulsky, David S.; Choi, Seung W.; Kirshblum, Steven C.

2015-01-01

Objective To develop a self-reported measure of the subjective impact of pressure ulcers on health-related quality of life (HRQOL) in individuals with spinal cord injury (SCI) as part of the SCI quality of life (SCI-QOL) measurement system. Design Grounded-theory based qualitative item development methods, large-scale item calibration testing, confirmatory factor analysis (CFA), and item response theory-based psychometric analysis. Setting Five SCI Model System centers and one Department of Veterans Affairs medical center in the United States. Participants Adults with traumatic SCI. Main Outcome Measures SCI-QOL Pressure Ulcers scale. Results 189 individuals with traumatic SCI who experienced a pressure ulcer within the past 7 days completed 30 items related to pressure ulcers. CFA confirmed a unidimensional pool of items. IRT analyses were conducted. A constrained Graded Response Model with a constant slope parameter was used to estimate item thresholds for the 12 retained items. Conclusions The 12-item SCI-QOL Pressure Ulcers scale is unique in that it is specifically targeted to individuals with spinal cord injury and at every stage of development has included input from individuals with SCI. Furthermore, use of CFA and IRT methods provide flexibility and precision of measurement. The scale may be administered in its entirety or as a 7-item “short form” and is available for both research and clinical practice. PMID:26010965

Applications for Micrographics in Large Scale Information Systems of the Future. Volume I: Part I. Summary. Part II. Five-Year Plan for DDC Micrographic Development Actions.

ERIC Educational Resources Information Center

Information Dynamics Corp., Reading, MA.

A study intended to provide the Defense Documentation Center (DDC) with a five-year plan for the development of improved and new microfiche products, services, and production capabilities is summarized in this report. In addition, the major findings, conclusions, and recommendations developed during the study are noted. The results of the research…

Data Intensive Scientific Workflows on a Federated Cloud: CRADA Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garzoglio, Gabriele

The Fermilab Scientific Computing Division and the KISTI Global Science Experimental Data Hub Center have built a prototypical large-scale infrastructure to handle scientific workflows of stakeholders to run on multiple cloud resources. The demonstrations have been in the areas of (a) Data-Intensive Scientific Workflows on Federated Clouds, (b) Interoperability and Federation of Cloud Resources, and (c) Virtual Infrastructure Automation to enable On-Demand Services.

Environmental Management Approach to Improve College Student and Community Relations to Reduce Binge and High-Risk Alcohol Use and Other Drug Problems. Prevention Update

ERIC Educational Resources Information Center

Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2011

2011-01-01

A central feature of the U.S. Department of Education's Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention is the promotion of multiple prevention strategies that affect campus and surrounding community environments as a whole and can, thereby, have a large-scale effect on the entire campus community. In outlining the…

Emory University: High-Throughput Protein-Protein Interaction Dataset for Lung Cancer-Associated Genes | Office of Cancer Genomics

Cancer.gov

To discover novel PPI signaling hubs for lung cancer, CTD2 Center at Emory utilized large-scale genomics datasets and literature to compile a set of lung cancer-associated genes. A library of expression vectors were generated for these genes and utilized for detecting pairwise PPIs with cell lysate-based TR-FRET assays in high-throughput screening format. Read the abstract.

Impacts of Social-Emotional Curricula on Three-Year-Olds: Exploratory Findings from the Head Start CARES Demonstration. Research Snapshot. OPRE Report 2014-78

ERIC Educational Resources Information Center

Hsueh, JoAnn; Lowenstein, Amy E.; Morris, Pamela; Mattera, Shira K.; Bangser, Michael

2014-01-01

This report presents exploratory impact findings for 3-year-olds from the Head Start CARES demonstration, a large-scale randomized controlled trial implemented in Head Start centers for one academic year across the country. The study was designed primarily to test the effects of the enhancements on 4-year-olds, but it also provides an opportunity…

Ubiquitous and Continuous Propagating Disturbances in the Solar Corona

NASA Astrophysics Data System (ADS)

Morgan, Huw; Hutton, Joseph

2018-02-01

A new processing method applied to Atmospheric Imaging Assembly/Solar Dynamic Observatory observations reveals continuous propagating faint motions throughout the corona. The amplitudes are small, typically 2% of the background intensity. An hour’s data are processed from four AIA channels for a region near disk center, and the motions are characterized using an optical flow method. The motions trace the underlying large-scale magnetic field. The motion vector field describes large-scale coherent regions that tend to converge at narrow corridors. Large-scale vortices can also be seen. The hotter channels have larger-scale regions of coherent motion compared to the cooler channels, interpreted as the typical length of magnetic loops at different heights. Regions of low mean and high time variance in velocity are where the dominant motion component is along the line of sight as a result of a largely vertical magnetic field. The mean apparent magnitude of the optical velocities are a few tens of km s‑1, with different distributions in different channels. Over time, the velocities vary smoothly between a few km s‑1 to 100 km s‑1 or higher, varying on timescales of minutes. A clear bias of a few km s‑1 toward positive x-velocities is due to solar rotation and may be used as calibration in future work. All regions of the low corona thus experience a continuous stream of propagating disturbances at the limit of both spatial resolution and signal level. The method provides a powerful new diagnostic tool for tracing the magnetic field, and to probe motions at sub-pixel scales, with important implications for models of heating and of the magnetic field.

Field Assessment Stroke Triage for Emergency Destination: A Simple and Accurate Prehospital Scale to Detect Large Vessel Occlusion Strokes.

PubMed

Lima, Fabricio O; Silva, Gisele S; Furie, Karen L; Frankel, Michael R; Lev, Michael H; Camargo, Érica C S; Haussen, Diogo C; Singhal, Aneesh B; Koroshetz, Walter J; Smith, Wade S; Nogueira, Raul G

2016-08-01

Patients with large vessel occlusion strokes (LVOS) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers. However, accurate stroke field triage remains challenging. We aimed to develop a simple field scale to identify LVOS. The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) scale was based on items of the National Institutes of Health Stroke Scale (NIHSS) with higher predictive value for LVOS and tested in the Screening Technology and Outcomes Project in Stroke (STOPStroke) cohort, in which patients underwent computed tomographic angiography within the first 24 hours of stroke onset. LVOS were defined by total occlusions involving the intracranial internal carotid artery, middle cerebral artery-M1, middle cerebral artery-2, or basilar arteries. Patients with partial, bihemispheric, and anterior+posterior circulation occlusions were excluded. Receiver operating characteristic curve, sensitivity, specificity, positive predictive value, and negative predictive value of FAST-ED were compared with the NIHSS, Rapid Arterial Occlusion Evaluation (RACE) scale, and Cincinnati Prehospital Stroke Severity (CPSS) scale. LVO was detected in 240 of the 727 qualifying patients (33%). FAST-ED had comparable accuracy to predict LVO to the NIHSS and higher accuracy than RACE and CPSS (area under the receiver operating characteristic curve: FAST-ED=0.81 as reference; NIHSS=0.80, P=0.28; RACE=0.77, P=0.02; and CPSS=0.75, P=0.002). A FAST-ED ≥4 had sensitivity of 0.60, specificity of 0.89, positive predictive value of 0.72, and negative predictive value of 0.82 versus RACE ≥5 of 0.55, 0.87, 0.68, and 0.79, and CPSS ≥2 of 0.56, 0.85, 0.65, and 0.78, respectively. FAST-ED is a simple scale that if successfully validated in the field, it may be used by medical emergency professionals to identify LVOS in the prehospital setting enabling rapid triage of patients. © 2016 American Heart Association, Inc.

Impact of the nursing home scale on residents' social engagement in South Korea.

PubMed

Yoon, Ju Young; Kim, Hongsoo; Jung, Young-Il; Ha, Jung-Hwa

2016-12-01

This study aimed to describe the levels of social engagement and to examine the relationship between the nursing home scale groups and social engagement in nursing homes in South Korea. A total of 314 residents were randomly selected from rosters provided by 10 nursing homes located in three metropolitan areas in South Korea. The outcome variable was social engagement measured by the Revised Index of Social Engagement (RISE), and the key independent variable was the nursing home scale (small, medium, and large). Individual factors (age, gender, activities of daily living and cognitive function, and depressive symptoms) and organizational factors (location, ownership, and staffing levels) were controlled in the model as covariates. Multilevel logistic regression was used in this study. About half of the residents (46%) in this study were not socially engaged in the nursing home (RISE=0) where they resided. Controlling for individual- and organizational-level factors, the nursing home facility size was a significant factor to predict the likelihood of residents' social engagement, with that the residents in large-scale nursing homes being less likely to be socially engaged than those in medium-scale nursing homes (odds ratio = 0.457; p-value = 0.005). This study supports evidence from previous studies that smaller-scale nursing homes are likely to provide more person-centered care compared to larger-scale nursing homes. Subsequent quality studies are needed to examine how the mechanisms for how smaller-scale nursing homes can enhance residents' social engagement in terms of care delivery processes.

Annual Research Briefs

NASA Technical Reports Server (NTRS)

Spinks, Debra (Compiler)

1997-01-01

This report contains the 1997 annual progress reports of the research fellows and students supported by the Center for Turbulence Research (CTR). Titles include: Invariant modeling in large-eddy simulation of turbulence; Validation of large-eddy simulation in a plain asymmetric diffuser; Progress in large-eddy simulation of trailing-edge turbulence and aeronautics; Resolution requirements in large-eddy simulations of shear flows; A general theory of discrete filtering for LES in complex geometry; On the use of discrete filters for large eddy simulation; Wall models in large eddy simulation of separated flow; Perspectives for ensemble average LES; Anisotropic grid-based formulas for subgrid-scale models; Some modeling requirements for wall models in large eddy simulation; Numerical simulation of 3D turbulent boundary layers using the V2F model; Accurate modeling of impinging jet heat transfer; Application of turbulence models to high-lift airfoils; Advances in structure-based turbulence modeling; Incorporating realistic chemistry into direct numerical simulations of turbulent non-premixed combustion; Effects of small-scale structure on turbulent mixing; Turbulent premixed combustion in the laminar flamelet and the thin reaction zone regime; Large eddy simulation of combustion instabilities in turbulent premixed burners; On the generation of vorticity at a free-surface; Active control of turbulent channel flow; A generalized framework for robust control in fluid mechanics; Combined immersed-boundary/B-spline methods for simulations of flow in complex geometries; and DNS of shock boundary-layer interaction - preliminary results for compression ramp flow.

Obscuring and Feeding Supermassive Black Holes with Evolving Nuclear Star Clusters

NASA Astrophysics Data System (ADS)

Schartmann, M.; Burkert, A.; Krause, M.; Camenzind, M.; Meisenheimer, K.; Davies, R. I.

2010-05-01

Recently, high-resolution observations made with the help of the near-infrared adaptive optics integral field spectrograph SINFONI at the VLT proved the existence of massive and young nuclear star clusters in the centers of a sample of Seyfert galaxies. With the help of high-resolution hydrodynamical simulations with the pluto code, we follow the evolution of such clusters, especially focusing on mass and energy feedback from young stars. This leads to a filamentary inflow of gas on large scales (tens of parsecs), whereas a turbulent and very dense disk builds up on the parsec scale. Here we concentrate on the long-term evolution of the nuclear disk in NGC 1068 with the help of an effective viscous disk model, using the mass input from the large-scale simulations and accounting for star formation in the disk. This two-stage modeling enables us to connect the tens-of-parsecs scale region (observable with SINFONI) with the parsec-scale environment (MIDI observations). At the current age of the nuclear star cluster, our simulations predict disk sizes of the order 0.8 to 0.9 pc, gas masses of order 106 M⊙, and mass transfer rates through the inner boundary of order 0.025 M⊙ yr-1, in good agreement with values derived from observations.

Lessons learned from cross-border medical response to the terrorist bombings in Tabba and Ras-el-Satan, Egypt, on 07 October 2004.

PubMed

Leiba, Adi; Blumenfeld, Amir; Hourvitz, Ariel; Weiss, Gali; Peres, Michal; Laor, Dani; Schwartz, Dagan; Arad, Jacob; Goldberg, Avishay; Levi, Yeheskel; Bar-Dayan, Yaron

2005-01-01

Large-scale, terrorist attacks can happen in peripheral areas, which are located close to a country's borders and far from its main medical facilities and involve multi-national casualties and responders. The objective of this study was to analyze the terrorist suicide bombings that occurred on 07 October 2004, near the Israeli-Egyptian border, as representative of such a complex scenario. Data from formal debriefings after the event were processed in order to learn about victim outcomes, resource utilization, critical events, and time course of the emergency response. A total of 185 injured survivors were repatriated: four were severely wounded, 13 were moderately injured, and 168 were mildly injured. Thirty-eight people died. A forward medical team landed at the border town's airport, which provided reinforcement in the field and in the local hospital. Israeli and Egyptian search and rescue teams collaborated at the destruction site. One-hundred sixty-eight injured patients arrived at the small border hospital that rapidly organized itself for the mass-casualty incident, operating as an evacuation "staging hospital". Twenty-three casualties secondarily were distributed to two major trauma centers in the south and the center of Israel, respectively, either by ambulance or by helicopter. Large-scale, terrorist attacks at a peripheral border zone can be handled by international collaboration, reinforcement of medical teams at the site itself and at the peripheral neighboring hospital, rapid rearrangement of an "evacuation hospital", and efficient transport to trauma centers by ambulances, helicopters, and other aircraft.

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research

PubMed Central

Becker, Christian M.; Laufer, Marc R.; Stratton, Pamela; Hummelshoj, Lone; Missmer, Stacey A.; Zondervan, Krina T.; Adamson, G. David; Adamson, G.D.; Allaire, C.; Anchan, R.; Becker, C.M.; Bedaiwy, M.A.; Buck Louis, G.M.; Calhaz-Jorge, C.; Chwalisz, K.; D'Hooghe, T.M.; Fassbender, A.; Faustmann, T.; Fazleabas, A.T.; Flores, I.; Forman, A.; Fraser, I.; Giudice, L.C.; Gotte, M.; Gregersen, P.; Guo, S.-W.; Harada, T.; Hartwell, D.; Horne, A.W.; Hull, M.L.; Hummelshoj, L.; Ibrahim, M.G.; Kiesel, L.; Laufer, M.R.; Machens, K.; Mechsner, S.; Missmer, S.A.; Montgomery, G.W.; Nap, A.; Nyegaard, M.; Osteen, K.G.; Petta, C.A.; Rahmioglu, N.; Renner, S.P.; Riedlinger, J.; Roehrich, S.; Rogers, P.A.; Rombauts, L.; Salumets, A.; Saridogan, E.; Seckin, T.; Stratton, P.; Sharpe-Timms, K.L.; Tworoger, S.; Vigano, P.; Vincent, K.; Vitonis, A.F.; Wienhues-Thelen, U.-H.; Yeung, P.P.; Yong, P.; Zondervan, K.T.

2014-01-01

Objective To standardize the recording of surgical phenotypic information on endometriosis and related sample collections obtained at laparoscopy, allowing large-scale collaborative research into the condition. Design An international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries. Setting Two workshops were conducted in 2013, bringing together 54 clinical, academic, and industry leaders in endometriosis research and management worldwide. Patient(s) None. Intervention(s) A postsurgical scoring sheet containing general and gynecological patient and procedural information, extent of disease, the location and type of endometriotic lesion, and any other findings was developed during several rounds of review. Comments and any systematic surgical data collection tools used in the reviewers' centers were incorporated. Main Outcome Measure(s) The development of a standard recommended (SSF) and minimum required (MSF) form to collect data on the surgical phenotype of endometriosis. Result(s) SSF and MSF include detailed descriptions of lesions, modes of procedures and sample collection, comorbidities, and potential residual disease at the end of surgery, along with previously published instruments such as the revised American Society for Reproductive Medicine and Endometriosis Fertility Index classification tools for comparison and validation. Conclusion(s) This is the first multicenter, international collaboration between academic centers and industry addressing standardization of phenotypic data collection for a specific disease. The Endometriosis Phenome and Biobanking Harmonisation Project SSF and MSF are essential tools to increase our understanding of the pathogenesis of endometriosis by allowing large-scale collaborative research into the condition. PMID:25150390

ATCA survey of ammonia in the galactic center: The temperatures of dense gas clumps between Sgr A* and Sgr B2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ott, Jürgen; Weiß, Axel; Henkel, Christian

We present a large-scale, interferometric survey of ammonia (1, 1) and (2, 2) toward the Galactic center observed with the Australia Telescope Compact Array. The survey covers Δℓ ∼ 1° (∼150 pc at an assumed distance of 8.5 kpc) and Δb ∼ 0.°2 (∼30 pc) which spans the region between the supermassive black hole Sgr A* and the massive star forming region Sgr B2. The resolution is ∼20'' (∼0.8 pc) and emission at scales ≳ 2' (≳ 3.2 pc) is filtered out due to missing interferometric short spacings. Consequently, the data represent the denser, compact clouds and disregards the large-scale,more » diffuse gas. Many of the clumps align with the 100 pc dust ring and mostly anti-correlate with 1.2 cm continuum emission. We present a kinetic temperature map of the dense gas. The temperature distribution peaks at ∼38 K with a width at half maximum between 18 K and 61 K (measurements sensitive within T {sub kin} ∼ 10-80 K). Larger clumps are on average warmer than smaller clumps which suggests internal heating sources. Our observations indicate that the circumnuclear disk ∼1.5 pc around Sgr A* is supplied with gas from the 20 km s{sup –1} molecular cloud. This gas is substantially cooler than gas ∼3-15 pc away from Sgr A*. We find a strong temperature gradient across Sgr B2. Ammonia column densities correlate well with SCUBA 850 μm fluxes, but the relation is shifted from the origin, which may indicate a requirement for a minimum amount of dust to form and shield ammonia. Around the Arches and Quintuplet clusters we find shell morphologies with UV-influenced gas in their centers, followed by ammonia and radio continuum layers.« less

Cyber Security and Reliability in a Digital Cloud

DTIC Science & Technology

2013-01-01

a higher utilization of servers, lower professional support staff needs, economies of scale for the physical facility, and the flexibility to locate...as  a  system,  the  DoD  can  achieve  the  economies  of scale typically associated with large data centers.  Recommendation 3: The DoD CIO and DISA...providers will help set  standards for secure cloud computing across the  economy .  Recommendation 7: The DoD CIO and DISA should participate in the

The influence of the Atlantic Warm Pool on the Florida panhandle sea breeze

USGS Publications Warehouse

Misra, V.; Moeller, L.; Stefanova, L.; Chan, S.; O'Brien, J. J.; Smith, T.J.; Plant, N.

2011-01-01

In this paper we examine the variations of the boreal summer season sea breeze circulation along the Florida panhandle coast from relatively high resolution (10 km) regional climate model integrations. The 23 year climatology (1979-2001) of the multidecadal dynamically downscaled simulations forced by the National Centers for Environmental Prediction-Department of Energy (NCEP-DOE) Reanalysis II at the lateral boundaries verify quite well with the observed climatology. The variations at diurnal and interannual time scales are also well simulated with respect to the observations. We show from composite analyses made from these downscaled simulations that sea breezes in northwestern Florida are associated with changes in the size of the Atlantic Warm Pool (AWP) on interannual time scales. In large AWP years when the North Atlantic Subtropical High becomes weaker and moves further eastward relative to the small AWP years, a large part of the southeast U.S. including Florida comes under the influence of relatively strong anomalous low-level northerly flow and large-scale subsidence consistent with the theory of the Sverdrup balance. This tends to suppress the diurnal convection over the Florida panhandle coast in large AWP years. This study is also an illustration of the benefit of dynamic downscaling in understanding the low-frequency variations of the sea breeze. Copyright 2011 by the American Geophysical Union.

Computational Issues in Damping Identification for Large Scale Problems

NASA Technical Reports Server (NTRS)

Pilkey, Deborah L.; Roe, Kevin P.; Inman, Daniel J.

1997-01-01

Two damping identification methods are tested for efficiency in large-scale applications. One is an iterative routine, and the other a least squares method. Numerical simulations have been performed on multiple degree-of-freedom models to test the effectiveness of the algorithm and the usefulness of parallel computation for the problems. High Performance Fortran is used to parallelize the algorithm. Tests were performed using the IBM-SP2 at NASA Ames Research Center. The least squares method tested incurs high communication costs, which reduces the benefit of high performance computing. This method's memory requirement grows at a very rapid rate meaning that larger problems can quickly exceed available computer memory. The iterative method's memory requirement grows at a much slower pace and is able to handle problems with 500+ degrees of freedom on a single processor. This method benefits from parallelization, and significant speedup can he seen for problems of 100+ degrees-of-freedom.

Low-speed wind-tunnel investigation of the longitudinal characteristics of a large-scale variable wing-sweep fighter model in the high-lift configuration

NASA Technical Reports Server (NTRS)

Eckert, W. T.; Maki, R. L.

1973-01-01

The low-speed characteristics of a large-scale model of the U. S. Navy/Grumman F-14A aircraft were studied in tests conducted in the Ames Research Center 40- by 80-Foot Wind Tunnel. The primary purpose of the program was the determination of lift and stability levels and landing approach attitude of the aircraft in its high-lift configuration. Tests were conducted at wing angles of attack between minus 2 deg and 30 deg with zero yaw. Data were taken at Reynolds numbers ranging from 3.48 million to 9.64 million based on a wing mean aerodynamic chord of 7.36 ft. The model configuration was changed as required to show the effects of glove slat, wing slat leading-edge radius, cold flow ducting, flap deflection, direct lift control (spoilers), horizontal tail, speed brake, landing gear and missiles.

Low-speed wind tunnel investigation of the lateral-directional characterisitcs of a large-scale variable wing-sweep fighter model in the high-lift configuration

NASA Technical Reports Server (NTRS)

Eckert, W. T.; Maki, R. L.

1973-01-01

The low-speed characteristics of a large-scale model of the F-14A aircraft were studied in tests conducted in the Ames Research Center 40- by 80-Foot Wind Tunnel. The primary purpose of the present tests was the determination of lateral-directional stability levels and control effectiveness of the aircraft in its high-lift configuration. Tests were conducted at wing angles of attack between minus 2 deg and 30 deg and with sideslip angles between minus 12 deg and 12 deg. Data were taken at a Reynolds number of 8.0 million based on a wing mean aerodynamic chord of 2.24 m (7.36 ft). The model configuration was changed as required to show the effects of direct lift control (spoilers) at yaw, yaw angle with speed brake deflected, and various amounts and combinations of roll control.

Experimental Investigation of a Large-Scale Low-Boom Inlet Concept

NASA Technical Reports Server (NTRS)

Hirt, Stefanie M.; Chima, Rodrick V.; Vyas, Manan A.; Wayman, Thomas R.; Conners, Timothy R.; Reger, Robert W.

2011-01-01

A large-scale low-boom inlet concept was tested in the NASA Glenn Research Center 8- x 6- foot Supersonic Wind Tunnel. The purpose of this test was to assess inlet performance, stability and operability at various Mach numbers and angles of attack. During this effort, two models were tested: a dual stream inlet designed to mimic potential aircraft flight hardware integrating a high-flow bypass stream; and a single stream inlet designed to study a configuration with a zero-degree external cowl angle and to permit surface visualization of the vortex generator flow on the internal centerbody surface. During the course of the test, the low-boom inlet concept was demonstrated to have high recovery, excellent buzz margin, and high operability. This paper will provide an overview of the setup, show a brief comparison of the dual stream and single stream inlet results, and examine the dual stream inlet characteristics.

Molecular clouds and the large-scale structure of the galaxy

NASA Technical Reports Server (NTRS)

Thaddeus, Patrick; Stacy, J. Gregory

1990-01-01

The application of molecular radio astronomy to the study of the large-scale structure of the Galaxy is reviewed and the distribution and characteristic properties of the Galactic population of Giant Molecular Clouds (GMCs), derived primarily from analysis of the Columbia CO survey, and their relation to tracers of Population 1 and major spiral features are described. The properties of the local molecular interstellar gas are summarized. The CO observing programs currently underway with the Center for Astrophysics 1.2 m radio telescope are described, with an emphasis on projects relevant to future comparison with high-energy gamma-ray observations. Several areas are discussed in which high-energy gamma-ray observations by the EGRET (Energetic Gamma-Ray Experiment Telescope) experiment aboard the Gamma Ray Observatory will directly complement radio studies of the Milky Way, with the prospect of significant progress on fundamental issues related to the structure and content of the Galaxy.

A streamlined collecting and preparation protocol for DNA barcoding of Lepidoptera as part of large-scale rapid biodiversity assessment projects, exemplified by the Indonesian Biodiversity Discovery and Information System (IndoBioSys)

PubMed Central

Hausmann, Axel; Cancian de Araujo, Bruno; Sutrisno, Hari; Peggie, Djunijanti; Schmidt, Stefan

2017-01-01

Abstract Here we present a general collecting and preparation protocol for DNA barcoding of Lepidoptera as part of large-scale rapid biodiversity assessment projects, and a comparison with alternative preserving and vouchering methods. About 98% of the sequenced specimens processed using the present collecting and preparation protocol yielded sequences with more than 500 base pairs. The study is based on the first outcomes of the Indonesian Biodiversity Discovery and Information System (IndoBioSys). IndoBioSys is a German-Indonesian research project that is conducted by the Museum für Naturkunde in Berlin and the Zoologische Staatssammlung München, in close cooperation with the Research Center for Biology – Indonesian Institute of Sciences (RCB-LIPI, Bogor). PMID:29134041

Large-Eddy Simulation of Aeroacoustic Applications

NASA Technical Reports Server (NTRS)

Pruett, C. David; Sochacki, James S.

1999-01-01

This report summarizes work accomplished under a one-year NASA grant from NASA Langley Research Center (LaRC). The effort culminates three years of NASA-supported research under three consecutive one-year grants. The period of support was April 6, 1998, through April 5, 1999. By request, the grant period was extended at no-cost until October 6, 1999. Its predecessors have been directed toward adapting the numerical tool of large-eddy simulation (LES) to aeroacoustic applications, with particular focus on noise suppression in subsonic round jets. In LES, the filtered Navier-Stokes equations are solved numerically on a relatively coarse computational grid. Residual stresses, generated by scales of motion too small to be resolved on the coarse grid, are modeled. Although most LES incorporate spatial filtering, time-domain filtering affords certain conceptual and computational advantages, particularly for aeroacoustic applications. Consequently, this work has focused on the development of subgrid-scale (SGS) models that incorporate time-domain filters.

Scale effects between body size and limb design in quadrupedal mammals.

PubMed

Kilbourne, Brandon M; Hoffman, Louwrens C

2013-01-01

Recently the metabolic cost of swinging the limbs has been found to be much greater than previously thought, raising the possibility that limb rotational inertia influences the energetics of locomotion. Larger mammals have a lower mass-specific cost of transport than smaller mammals. The scaling of the mass-specific cost of transport is partly explained by decreasing stride frequency with increasing body size; however, it is unknown if limb rotational inertia also influences the mass-specific cost of transport. Limb length and inertial properties--limb mass, center of mass (COM) position, moment of inertia, radius of gyration, and natural frequency--were measured in 44 species of terrestrial mammals, spanning eight taxonomic orders. Limb length increases disproportionately with body mass via positive allometry (length ∝ body mass(0.40)); the positive allometry of limb length may help explain the scaling of the metabolic cost of transport. When scaled against body mass, forelimb inertial properties, apart from mass, scale with positive allometry. Fore- and hindlimb mass scale according to geometric similarity (limb mass ∝ body mass(1.0)), as do the remaining hindlimb inertial properties. The positive allometry of limb length is largely the result of absolute differences in limb inertial properties between mammalian subgroups. Though likely detrimental to locomotor costs in large mammals, scale effects in limb inertial properties appear to be concomitant with scale effects in sensorimotor control and locomotor ability in terrestrial mammals. Across mammals, the forelimb's potential for angular acceleration scales according to geometric similarity, whereas the hindlimb's potential for angular acceleration scales with positive allometry.

Scale Effects between Body Size and Limb Design in Quadrupedal Mammals

PubMed Central

Kilbourne, Brandon M.; Hoffman, Louwrens C.

2013-01-01

Recently the metabolic cost of swinging the limbs has been found to be much greater than previously thought, raising the possibility that limb rotational inertia influences the energetics of locomotion. Larger mammals have a lower mass-specific cost of transport than smaller mammals. The scaling of the mass-specific cost of transport is partly explained by decreasing stride frequency with increasing body size; however, it is unknown if limb rotational inertia also influences the mass-specific cost of transport. Limb length and inertial properties – limb mass, center of mass (COM) position, moment of inertia, radius of gyration, and natural frequency – were measured in 44 species of terrestrial mammals, spanning eight taxonomic orders. Limb length increases disproportionately with body mass via positive allometry (length ∝ body mass0.40); the positive allometry of limb length may help explain the scaling of the metabolic cost of transport. When scaled against body mass, forelimb inertial properties, apart from mass, scale with positive allometry. Fore- and hindlimb mass scale according to geometric similarity (limb mass ∝ body mass1.0), as do the remaining hindlimb inertial properties. The positive allometry of limb length is largely the result of absolute differences in limb inertial properties between mammalian subgroups. Though likely detrimental to locomotor costs in large mammals, scale effects in limb inertial properties appear to be concomitant with scale effects in sensorimotor control and locomotor ability in terrestrial mammals. Across mammals, the forelimb's potential for angular acceleration scales according to geometric similarity, whereas the hindlimb's potential for angular acceleration scales with positive allometry. PMID:24260117

“Local” Dark Energy Outflows Around Galaxy Groups and Rich Clusters

NASA Astrophysics Data System (ADS)

Byrd, Gene G.; Chernin, A. D.; Teerikorpi, P.; Dolgachev, V. P.; Kanter, A. A.; Domozhilova, L. M.; Valtonen, M.

2013-01-01

First detected at large Gpc distances, dark energy is a vacuum energy formulated as Einstein's cosmological constant, Λ. We have found its effects on “small” 1-3 Mpc scales in our Local Group. We have now found these effects in other nearby groups using member Doppler shifts and 3D distances from group centers (Cen A-M83; M81-M82; CV I). For the larger 20-30 Mpc Virgo and Fornax clusters, we now have found similar effects. Observationally, for both groups and clusters, gravity dominates a bound central system. The system gravitation and dark energy create a “zero-gravity” radius (R_{ZG}) from the center where the two balance. Smaller members bound inside R_{ZG} may be pulled out along with the less bound members which recede farther. A linear increase of recession with distance results which approaches a linear global Hubble law. These outflows are seen around groups in cosmological simulations which include galaxies as small as ~10^{-4} of the group mass. Scaled plots of asymptotic recessional velocity, V/(H(R_{ZG})), versus distance/ R_{ZG} of the outer galaxies are very similar for both the small groups and large clusters. This similarity on 1-30 Mpc scales suggests that a quasi-stationary bound central component and an expanding outflow applies to a wide range of groups and clusters due to small scale action of dark energy. Our new text book: Byrd, G., Chernin, A., Terrikorpi, P. and Valtonen, M. 2012, "Paths to Dark Energy: Theory and Observation," de Gruyter, Berlin/Boston, contains background and cosmological simulation plots. Group data and scaled plots are in our new article: A. D. Chernin, P. Teerikorpi, V. P. Dolgachev, A. A. Kanter, L. M. Domozhilova, M. J. Valtonen, and G. G. Byrd, 2012, Astronomy Reports, Vol. 56 , p. 653-669.

A construct-driven investigation of gender differences in a leadership-role assessment center.

PubMed

Anderson, Neil; Lievens, Filip; van Dam, Karen; Born, Marise

2006-05-01

This study examined gender differences in a large-scale assessment center for officer entry in the British Army. Subgroup differences were investigated for a sample of 1,857 candidates: 1,594 men and 263 women. A construct-driven approach was chosen (a) by examining gender differences at the construct level, (b) by formulating a priori hypotheses about which constructs would be susceptible to gender effects, and (c) by using both effect size statistics and latent mean analyses to investigate gender differences in assessment center ratings. Results showed that female candidates were rated notably higher on constructs reflecting an interpersonally oriented leadership style (i.e., oral communication and interaction) and on drive and determination. These results are discussed in light of role congruity theory and of the advantages of using latent mean analyses.

The Stability Of Disk Barred Galaxies Over the Past 7 Billion Years

NASA Astrophysics Data System (ADS)

Tapia, Amauri; Simmons, Brooke

2017-01-01

A recently released model of interacting disk galaxies provides a hypothesis for the origins of off center bars in disks. No systematic search for offset bars in the early universe has yet been undertaken. The Galaxy Zoo project has produced data regarding the large-scale bars of many galaxies. Using this data alongside images collected by the Hubble Space Telescope and other sources, we have examined 5190 galaxies for signatures of off-centered bars. Less than 5 percent of the sample shows clear signs of an offset bar. We describe their overall properties of this sub-sample and compare the properties of galaxies with offset bars to those with centered bars. We assess the feasibility of the proposed model and place these galaxies in the context of the overall evolution of galaxies.

Utilizing the dynamic stark shift as a probe for dielectric relaxation in photosynthetic reaction centers during charge separation.

PubMed

Guo, Zhi; Lin, Su; Woodbury, Neal W

2013-09-26

In photosynthetic reaction centers, the electric field generated by light-induced charge separation produces electrochromic shifts in the transitions of reaction center pigments. The extent of this Stark shift indirectly reflects the effective field strength at a particular cofactor in the complex. The dynamics of the effective field strength near the two monomeric bacteriochlorophylls (BA and BB) in purple photosynthetic bacterial reaction centers has been explored near physiological temperature by monitoring the time-dependent Stark shift during charge separation (dynamic Stark shift). This dynamic Stark shift was determined through analysis of femtosecond time-resolved absorbance change spectra recorded in wild type reaction centers and in four mutants at position M210. In both wild type and the mutants, the kinetics of the dynamic Stark shift differ from those of electron transfer, though not in the same way. In wild type, the initial electron transfer and the increase in the effective field strength near the active-side monomer bacteriochlorophyll (BA) occur in synchrony, but the two signals diverge on the time scale of electron transfer to the quinone. In contrast, when tyrosine is replaced by aspartic acid at M210, the kinetics of the BA Stark shift and the initial electron transfer differ, but transfer to the quinone coincides with the decay of the Stark shift. This is interpreted in terms of differences in the dynamics of the local dielectric environment between the mutants and the wild type. In wild type, comparison of the Stark shifts associated with BA and BB on the two quasi-symmetric halves of the reaction center structure confirm that the effective dielectric constants near these cofactors are quite different when the reaction center is in the state P(+)QA(-), as previously determined by Steffen et al. at 1.5 K (Steffen, M. A.; et al. Science 1994, 264, 810-816). However, it is not possible to determine from static, low-temperature measurments if the difference in the effective dielectric constant between the two sides of the reaction center is manifest on the time scale of initial electron transfer. By comparing directly the Stark shift dynamics of the ground-state spectra of the two monomer bacteriochlorophylls, it is evident that there is, in fact, a large dielectric difference between protein environments of the two quasi-symmetric electron-transfer branches on the time scale of initial electron transfer and that the effective dielectric constant in the region continues to evolve on a time scale of hundreds of picoseconds.

Probing high scale physics with top quarks at the Large Hadron Collider

NASA Astrophysics Data System (ADS)

Dong, Zhe

With the Large Hadron Collider (LHC) running at TeV scale, we are expecting to find the deviations from the Standard Model in the experiments, and understanding what is the origin of these deviations. Being the heaviest elementary particle observed so far in the experiments with the mass at the electroweak scale, top quark is a powerful probe for new phenomena of high scale physics at the LHC. Therefore, we concentrate on studying the high scale physics phenomena with top quark pair production or decay at the LHC. In this thesis, we study the discovery potential of string resonances decaying to t/tbar final state, and examine the possibility of observing baryon-number-violating top-quark production or decay, at the LHC. We point out that string resonances for a string scale below 4 TeV can be detected via the t/tbar channel, by reconstructing center-of-mass frame kinematics of the resonances from either the t/tbar semi-leptonic decay or recent techniques of identifying highly boosted tops. For the study of baryon-number-violating processes, by a model independent effective approach and focusing on operators with minimal mass-dimension, we find that corresponding effective coefficients could be directly probed at the LHC already with an integrated luminosity of 1 inverse femtobarns at 7 TeV, and further constrained with 30 (100) inverse femtobarns at 7 (14) TeV.

A Metascalable Computing Framework for Large Spatiotemporal-Scale Atomistic Simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nomura, K; Seymour, R; Wang, W

2009-02-17

A metascalable (or 'design once, scale on new architectures') parallel computing framework has been developed for large spatiotemporal-scale atomistic simulations of materials based on spatiotemporal data locality principles, which is expected to scale on emerging multipetaflops architectures. The framework consists of: (1) an embedded divide-and-conquer (EDC) algorithmic framework based on spatial locality to design linear-scaling algorithms for high complexity problems; (2) a space-time-ensemble parallel (STEP) approach based on temporal locality to predict long-time dynamics, while introducing multiple parallelization axes; and (3) a tunable hierarchical cellular decomposition (HCD) parallelization framework to map these O(N) algorithms onto a multicore cluster based onmore » hybrid implementation combining message passing and critical section-free multithreading. The EDC-STEP-HCD framework exposes maximal concurrency and data locality, thereby achieving: (1) inter-node parallel efficiency well over 0.95 for 218 billion-atom molecular-dynamics and 1.68 trillion electronic-degrees-of-freedom quantum-mechanical simulations on 212,992 IBM BlueGene/L processors (superscalability); (2) high intra-node, multithreading parallel efficiency (nanoscalability); and (3) nearly perfect time/ensemble parallel efficiency (eon-scalability). The spatiotemporal scale covered by MD simulation on a sustained petaflops computer per day (i.e. petaflops {center_dot} day of computing) is estimated as NT = 2.14 (e.g. N = 2.14 million atoms for T = 1 microseconds).« less

Status of DSMT research program

NASA Technical Reports Server (NTRS)

Mcgowan, Paul E.; Javeed, Mehzad; Edighoffer, Harold H.

1991-01-01

The status of the Dynamic Scale Model Technology (DSMT) research program is presented. DSMT is developing scale model technology for large space structures as part of the Control Structure Interaction (CSI) program at NASA Langley Research Center (LaRC). Under DSMT a hybrid-scale structural dynamics model of Space Station Freedom was developed. Space Station Freedom was selected as the focus structure for DSMT since the station represents the first opportunity to obtain flight data on a complex, three-dimensional space structure. Included is an overview of DSMT including the development of the space station scale model and the resulting hardware. Scaling technology was developed for this model to achieve a ground test article which existing test facilities can accommodate while employing realistically scaled hardware. The model was designed and fabricated by the Lockheed Missile and Space Co., and is assembled at LaRc for dynamic testing. Also, results from ground tests and analyses of the various model components are presented along with plans for future subassembly and matted model tests. Finally, utilization of the scale model for enhancing analysis verification of the full-scale space station is also considered.

The proximity of hotspots to convergent and divergent plate boundaries

NASA Technical Reports Server (NTRS)

Weinstein, Stuart A.; Olson, Peter L.

1989-01-01

An analysis of four different hotspot distributions, ranging from Morgan's (1972) original list of 19 to Vogt's (1981) list of 117 reveals that the hotspots are preferentially located near divergent plate boundaries. The probability of this proximity occurring by chance alone is quite remote, less than 0.01 for all four hotspot distributions. The same analysis also reveals that the hotspots are preferentially excluded from regions near convergent plate boundaries. The probability of this exclusion occurring by chance alone is 0.1 or less for three out of the four distributions examined. We interpret this behavior as being a consequence of the effects of large scale convective circulation on ascending mantle plumes. Mantle thermal plumes, the most probable source of hotspots, arise from instabilities in a basal thermal boundary layer. Plumes are suppressed from regions beneath convergent boundaries by descending flow and are entrained into the upwelling flow beneath spreading centers. Plate-scale convective circulation driven by subduction may also advect mantle thermal plumes toward spreading centers.

Large-Scale Flow Structure in Turbulent Nonpremixed Flames under Normal- And Low-Gravity Conditions

NASA Technical Reports Server (NTRS)

Clemens, N. T.; Idicheria, C. A.; Boxx, I. G.

2001-01-01

It is well known that buoyancy has a major influence on the flow structure of turbulent nonpremixed jet flames. Buoyancy acts by inducing baroclinic torques, which generate large-scale vortical structures that can significantly modify the flow field. Furthermore, some suggest that buoyancy can substantially influence the large-scale structure of even nominally momentum-dominated flames, since the low velocity flow outside of the flame will be more susceptible to buoyancy effects. Even subtle buoyancy effects may be important because changes in the large-scale structure affects the local entrainment and fluctuating strain rate, and hence the structure of the flame. Previous studies that have compared the structure of normal- and micro-gravity nonpremixed jet flames note that flames in microgravity are longer and wider than in normal-gravity. This trend was observed for jet flames ranging from laminar to turbulent regimes. Furthermore, imaging of the flames has shown possible evidence of helical instabilities and disturbances starting from the base of the flame in microgravity. In contrast, these characteristics were not observed in normal-gravity. The objective of the present study is to further advance our knowledge of the effects of weak levels of buoyancy on the structure of transitional and turbulent nonpremixed jet flames. In later studies we will utilize the drop tower facilities at NASA Glenn Research Center (GRC), but the preliminary work described in this paper was conducted using the 1.25-second drop tower located at the University of Texas at Austin. A more detailed description of these experiments can be found in Idicheria et al.

KSC-2011-8238

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida negotiates the on-ramp at the intersection of NASA Causeway and Kennedy Parkway to gain entrance to the northbound roadways on the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8242

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida arrives at the foot of the on-ramp at the intersection of NASA Causeway and Kennedy Parkway to gain entrance to the northbound roadways on the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8240

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida moves along the on-ramp from NASA Causeway to Kennedy Parkway to gain entrance to the northbound roadways on the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8237

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida uses the on-ramp at the intersection of NASA Causeway and Kennedy Parkway to gain entrance to the northbound roadways on the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8241

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida monopolizes the on-ramp at the intersection of NASA Causeway and Kennedy Parkway to gain entrance to the northbound roadways on the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8239

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida creeps along the on-ramp from NASA Causeway to Kennedy Parkway to gain entrance to the northbound roadways on the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8235

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – Once it has passed the security gate, the high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida changes lanes as it rolls onto the center. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The model is being moved from the visitor complex to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

RIKEN BNL Research Center

NASA Astrophysics Data System (ADS)

Samios, Nicholas

2014-09-01

Since its inception in 1997, the RIKEN BNL Research Center (RBRC) has been a major force in the realms of Spin Physics, Relativistic Heavy Ion Physics, large scale Computing Physics and the training of a new generation of extremely talented physicists. This has been accomplished through the recruitment of an outstanding non-permanent staff of Fellows and Research associates in theory and experiment. RBRC is now a mature organization that has reached a steady level in the size of scientific and support staff while at the same time retaining its vibrant youth. A brief history of the scientific accomplishments and contributions of the RBRC physicists will be presented as well as a discussion of the unique RBRC management structure.

Optimization of a Monte Carlo Model of the Transient Reactor Test Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Kristin; DeHart, Mark; Goluoglu, Sedat

2017-03-01

The ultimate goal of modeling and simulation is to obtain reasonable answers to problems that don’t have representations which can be easily evaluated while minimizing the amount of computational resources. With the advances during the last twenty years of large scale computing centers, researchers have had the ability to create a multitude of tools to minimize the number of approximations necessary when modeling a system. The tremendous power of these centers requires the user to possess an immense amount of knowledge to optimize the models for accuracy and efficiency.This paper seeks to evaluate the KENO model of TREAT to optimizemore » calculational efforts.« less

Rocket University at KSC

NASA Technical Reports Server (NTRS)

Sullivan, Steven J.

2014-01-01

"Rocket University" is an exciting new initiative at Kennedy Space Center led by NASA's Engineering and Technology Directorate. This hands-on experience has been established to develop, refine & maintain targeted flight engineering skills to enable the Agency and KSC strategic goals. Through "RocketU", KSC is developing a nimble, rapid flight engineering life cycle systems knowledge base. Ongoing activities in RocketU develop and test new technologies and potential customer systems through small scale vehicles, build and maintain flight experience through balloon and small-scale rocket missions, and enable a revolving fresh perspective of engineers with hands on expertise back into the large scale NASA programs, providing a more experienced multi-disciplined set of systems engineers. This overview will define the Program, highlight aspects of the training curriculum, and identify recent accomplishments and activities.

Scaling behavior in exclusive meson photoproduction from Jefferson Lab at large momentum transfers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dey, Biplab

2014-07-01

With the availability of new high-statistics and wide-angle measurements for several exclusive non-πN meson photoproduction channels from Jefferson Lab, we examine the fundamental scaling law of 90° scattering in QCD that was originally derived in the high-energy perturbative limit. The data show scaling to be prominently visible even in the medium-energy domain of 2.5 GeV ≲√s≲2.84 GeV, where √s is the center-of-mass energy. While constituent quark exchange suffices for pseudoscalar mesons, additional gluon exchanges from higher Fock states of the hadronic wave functions appear be needed for vector-meson production. Finally, the case of the Φ(1020), where two-gluon exchanges are knownmore » to dominate, is especially illuminating.« less

Effective control parameters in a deep convection scheme for improved simulation of the Madden-Julian oscillation

NASA Astrophysics Data System (ADS)

Choi, Jin-Ho; Seo, Kyong-Hwan

2017-06-01

This work seeks to find the most effective parameters in a deep convection scheme (relaxed Arakawa-Schubert scheme) of the National Centers of Environmental Prediction Climate Forecast System model for improved simulation of the Madden-Julian Oscillation (MJO). A suite of sensitivity experiments are performed by changing physical components such as the relaxation parameter of mass flux for adjustment of the environment, the evaporation rate from large-scale precipitation, the moisture trigger threshold using relative humidity of the boundary layer, and the fraction of re-evaporation of convective (subgrid-scale) rainfall. Among them, the last two parameters are found to produce a significant improvement. Increasing the strength of these two parameters reduces light rainfall that inhibits complete formation of the tropical convective system or supplies more moisture that help increase a potential energy to large-scale environment in the lower troposphere (especially at 700 hPa), leading to moisture preconditioning favorable for further development and eastward propagation of the MJO. In a more humid environment, more organized MJO structure (i.e., space-time spectral signal, eastward propagation, and tilted vertical structure) is produced.

Disruption of posteromedial large-scale neural communication predicts recovery from coma

PubMed Central

de Pasquale, Francesco; Vuillaume, Corine; Riu, Beatrice; Loubinoux, Isabelle; Geeraerts, Thomas; Seguin, Thierry; Bounes, Vincent; Fourcade, Olivier; Demonet, Jean-Francois; Péran, Patrice

2015-01-01

Objective: We hypothesize that the major consciousness deficit observed in coma is due to the breakdown of long-range neuronal communication supported by precuneus and posterior cingulate cortex (PCC), and that prognosis depends on a specific connectivity pattern in these networks. Methods: We compared 27 prospectively recruited comatose patients who had severe brain injury (Glasgow Coma Scale score <8; 14 traumatic and 13 anoxic cases) with 14 age-matched healthy participants. Standardized clinical assessment and fMRI were performed on average 4 ± 2 days after withdrawal of sedation. Analysis of resting-state fMRI connectivity involved a hypothesis-driven, region of interest–based strategy. We assessed patient outcome after 3 months using the Coma Recovery Scale–Revised (CRS-R). Results: Patients who were comatose showed a significant disruption of functional connectivity of brain areas spontaneously synchronized with PCC, globally notwithstanding etiology. The functional connectivity strength between PCC and medial prefrontal cortex (mPFC) was significantly different between comatose patients who went on to recover and those who eventually scored an unfavorable outcome 3 months after brain injury (Kruskal-Wallis test, p < 0.001; linear regression between CRS-R and PCC-mPFC activity coupling at rest, Spearman ρ = 0.93, p < 0.003). Conclusion: In both etiology groups (traumatic and anoxic), changes in the connectivity of PCC-centered, spontaneously synchronized, large-scale networks account for the loss of external and internal self-centered awareness observed during coma. Sparing of functional connectivity between PCC and mPFC may predict patient outcome, and further studies are needed to substantiate this potential prognosis biomarker. PMID:26561296

Some practical observations on the accelerated testing of Nickel-Cadmium Cells

NASA Technical Reports Server (NTRS)

Mcdermott, P. P.

1979-01-01

A large scale test of 6.0 Ah Nickel-Cadmium Cells conducted at the Naval Weapons Support Center, Crane, Indiana has demonstrated a methodology for predicting battery life based on failure data from cells cycled in an accelerated mode. After examining eight variables used to accelerate failure, it was determined that temperature and depth of discharge were the most reliable and efficient parameters for use in accelerating failure and for predicting life.

NASA's Pleiades Supercomputer Crunches Data For Groundbreaking Analysis and Visualizations

NASA Image and Video Library

2016-11-23

The Pleiades supercomputer at NASA's Ames Research Center, recently named the 13th fastest computer in the world, provides scientists and researchers high-fidelity numerical modeling of complex systems and processes. By using detailed analyses and visualizations of large-scale data, Pleiades is helping to advance human knowledge and technology, from designing the next generation of aircraft and spacecraft to understanding the Earth's climate and the mysteries of our galaxy.

FARMS: The Flexible Agricultural Robotics Manipulator

NASA Technical Reports Server (NTRS)

Gill, Paul S.

1991-01-01

A technology utilization project was established with the Marshall Space Flight Center and the University of Georgia to develop an Earth-based, robotic end effector to process live plant (geranium) material which will improve productivity and efficiency in agricultural systems such as commercial nurseries and greenhouse systems. The aim is to apply this technology to NASA's presence in space, including permanently manned space stations and manned planetary communities requiring large scale food production needs.

The Comet Halley archive: Summary volume

NASA Technical Reports Server (NTRS)

Sekanina, Zdenek (Editor); Fry, Lori (Editor)

1991-01-01

The contents are as follows: The Organizational History of the International Halley Watch; Operations of the International Halley Watch from a Lead Center Perspective; The Steering Group; Astrometry Network; Infrared Studies Network; Large-Scale Phenomena Network; Meteor Studies Network; Near-Nucleus Studies Network; Photometry and Polarimetry Network; Radio Science Network; Spectroscopy and Spectrophotometry Network; Amateur Observation Network; Use of the CD-ROM Archive; The 1986 Passage of Comet Halley; and Recent Observations of Comet Halley.

Inquiring Minds Want to Know: Progress Report on SCALE-UP Physics at Penn State Erie

NASA Astrophysics Data System (ADS)

Hall, Jonathan

2008-03-01

SCALE-UP (Student Centered Activities for Large Enrollment University Programs) is a ``studio'' approach to learning developed by Bob Beichner at North Carolina State University. SCALE-UP was adapted for teaching and learning in the introductory calculus-based mechanics course at Penn State Erie, The Behrend College, starting in Spring 2007. We are presently doing quantitative and qualitative research on using inquiry-based learning with first year college students, in particular how it effects female students and students from groups that are traditionally under-represented in STEM fields. Using field notes of observations of the classes, focus groups, and the collection of quantitative data, the feedback generated by the research is also being used to improve the delivery of the course, and in the planning of adopting SCALE-UP to the second semester course on electromagnetism in the Fall 2008 semester.

The fuelling of active galactic nuclei

NASA Technical Reports Server (NTRS)

Shlosman, Isaac; Begelman, Mitchell C.; Frank, Julian

1990-01-01

Accretion mechanisms for powering the central engines of active galactic nuclei (AGN) and possible sources of fuel are reviewed. It is a argued that the interstellar matter in the main body of the host galaxy is channeled toward the center, and the problem of angular momentum transport is addressed. Thin accretion disks are not a viable means of delivering fuel to luminous AGN on scales much larger than a parsec because of the long inflow time and effects of self-gravity. There are also serious obstacles to maintaining and regulating geometrically thick, hot accretion flows. The role of nonaxisymmetric perturbations of the gravitational potential on galactic scales and their triggers is emphasized. A unified model is outlined for fueling AGN, in which the inflow on large scales is driven by gravitational torques, and on small scales forms a mildly self-gravitating disk of clouds with inflow driven by magnetic torques or cloud-cloud collisions.

Cold Episodes, Their Precursors and Teleconnections in the Central Peruvian Andes (1958-2009)

NASA Astrophysics Data System (ADS)

Sulca, J. C.; Vuille, M. F.; Trasmonte, G.; Silva, Y.; Takahashi, K.

2014-12-01

The Mantaro valley (MV) is located in the central Peruvian Andes. Occasionally, cold episodes are observed during the austral summer (January-March), which strongly damage crops. However, little is known about the causes and impacts of such cold episodes in the MV. The main goal of this study is thus to characterize cold episodes in the MV and assess their large-scale circulation and teleconnections over South America (SA) during austral summer. To identify cold events in the MV daily minimum temperature for the period 1958-2009 from Huayao station, located within the MV was used. We defined a cold episode as the period when daily minimum temperature drops below the 10-percentile for at least one day. Several gridded reanalysis and satellite products were used to characterize the large-scale circulation, cloud cover and rainfall over SA associated with these events for same period. Cold episodes in the MV are associated with positive OLR anomalies, which extend over much of the central Andes, indicating reduced convective cloud cover during these extremes, but also affirm the large-scale nature of these events. At the same time, northeastern Brazil (NEB) registers negative OLR anomalies, strong convective activity and enhanced cloud cover because displacement of the South Atlantic Convergence Zone (SACZ) toward the northeast of its climatologic position. Further, it is associated with a weakening of the Bolivian High - Nordeste Low (BH-NL) system at upper levels, but also influenced by a low-level migratory high-pressure center develops at 30°S, 50°W; propagating from mid- to low latitudes as part of an extratropical Rossby wave train. In conclusion, cold episodes in the MV appear to be caused by radiative cooling associated with reduced cloudiness, rather than cold air advection. The reduced cloud cover in turn results from a robust large-scale pattern of westerly wind anomalies over central Peruvian Andes, inhibiting moisture influx, convective activity and hence cloud formation. At the same time NEB registers strong convective activity and enhanced cloud cover. This dipole is caused by a weakening of BH-NL system at upper levels, which is associated with a low-level migratory high-pressure center, propagating from mid- to low latitudes as part of an extratropical Rossby wave train.

Solar powered oxygen systems in remote health centers in Papua New Guinea: a large scale implementation effectiveness trial

PubMed Central

Duke, Trevor; Hwaihwanje, Ilomo; Kaupa, Magdalynn; Karubi, Jonah; Panauwe, Doreen; Sa’avu, Martin; Pulsan, Francis; Prasad, Peter; Maru, Freddy; Tenambo, Henry; Kwaramb, Ambrose; Neal, Eleanor; Graham, Hamish; Izadnegahdar, Rasa

2017-01-01

Background Pneumonia is the largest cause of child deaths in Papua New Guinea (PNG), and hypoxaemia is the major complication causing death in childhood pneumonia, and hypoxaemia is a major factor in deaths from many other common conditions, including bronchiolitis, asthma, sepsis, malaria, trauma, perinatal problems, and obstetric emergencies. A reliable source of oxygen therapy can reduce mortality from pneumonia by up to 35%. However, in low and middle income countries throughout the world, improved oxygen systems have not been implemented at large scale in remote, difficult to access health care settings, and oxygen is often unavailable at smaller rural hospitals or district health centers which serve as the first point of referral for childhood illnesses. These hospitals are hampered by lack of reliable power, staff training and other basic services. Methods We report the methodology of a large implementation effectiveness trial involving sustainable and renewable oxygen and power systems in 36 health facilities in remote rural areas of PNG. The methodology is a before–and after evaluation involving continuous quality improvement, and a health systems approach. We describe this model of implementation as the considerations and steps involved have wider implications in health systems in other countries. Results The implementation steps include: defining the criteria for where such an intervention is appropriate, assessment of power supplies and power requirements, the optimal design of a solar power system, specifications for oxygen concentrators and other oxygen equipment that will function in remote environments, installation logistics in remote settings, the role of oxygen analyzers in monitoring oxygen concentrator performance, the engineering capacity required to sustain a program at scale, clinical guidelines and training on oxygen equipment and the treatment of children with severe respiratory infection and other critical illnesses, program costs, and measurement of processes and outcomes to support continuous quality improvement. Conclusions This study will evaluate the feasibility and sustainability issues in improving oxygen systems and providing reliable power on a large scale in remote rural settings in PNG, and the impact of this on child mortality from pneumonia over 3 years post–intervention. Taking a continuous quality improvement approach can be transformational for remote health services. PMID:28567280

The use of a biplot in studying outcomes after stroke.

PubMed

De Wit, Liesbet; Molas, Marek; Dejaeger, Eddy; De Weerdt, Willy; Feys, Hilde; Jenni, Walter; Lincoln, Nadina; Putman, Koen; Schupp, Wilfried; Lesaffre, Emmanuel

2009-10-01

This study aimed to unravel the multidimensional profile of stroke outcomes by investigating the global correlation structure of motor, functional, and emotional problems of patients, as well as their caregivers' strain, at 6 months after stroke. Potential differential associations based on patients' level of functioning on admission to the rehabilitation center were analyzed. Data were collected within the CERISE-study (Collaborative Evaluation of Rehabilitation in Stroke across Europe). Six months after stroke, the Rivermead Motor Assessment (RMA), Extended Activities of Daily Living (EADL), Hospital Anxiety and Depression Scale-Anxiety (HADS-A) and Hospital Anxiety and Depression Scale-Depression (HADS-D), EuroQol-Health State (EQ-HS), EuroQol-Visual Analogue Scale (EQ-VAS), and Caregiver Strain Index (CSI) were administered. Patients were classified into 3 categories according to their Barthel Index (BI) score on admission to the rehabilitation center. Principal component analysis was carried out, and a biplot was constructed. Data were available on 510 patients. One cluster was formed by RMA and EADL, and a second one by HADS-A, HADS-D, and EQ-VAS. EQ-HS was situated between these two. CSI formed a third dimension. Patients with low BI scores on admission to the rehabilitation center had higher HADS-A and HADS-D scores 6 months after stroke. High BI scores were associated with large variations in HADS-A and HADS-D scores. This novel biplot strategy for rehabilitation studies revealed 2 clusters: one of motor/functional problems and one of emotional problems. Patients with mild functional deficit measured on admission to the rehabilitation center can suffer from mild to severe anxiety and depression at 6 months poststroke. Screening for emotional disorders in all patients is recommended.

High-uniformity centimeter-wide Si etching method for MEMS devices with large opening elements

NASA Astrophysics Data System (ADS)

Okamoto, Yuki; Tohyama, Yukiya; Inagaki, Shunsuke; Takiguchi, Mikio; Ono, Tomoki; Lebrasseur, Eric; Mita, Yoshio

2018-04-01

We propose a compensated mesh pattern filling method to achieve highly uniform wafer depth etching (over hundreds of microns) with a large-area opening (over centimeter). The mesh opening diameter is gradually changed between the center and the edge of a large etching area. Using such a design, the etching depth distribution depending on sidewall distance (known as the local loading effect) inversely compensates for the over-centimeter-scale etching depth distribution, known as the global or within-die(chip)-scale loading effect. Only a single DRIE with test structure patterns provides a micro-electromechanical systems (MEMS) designer with the etched depth dependence on the mesh opening size as well as on the distance from the chip edge, and the designer only has to set the opening size so as to obtain a uniform etching depth over the entire chip. This method is useful when process optimization cannot be performed, such as in the cases of using standard conditions for a foundry service and of short turn-around-time prototyping. To demonstrate, a large MEMS mirror that needed over 1 cm2 of backside etching was successfully fabricated using as-is-provided DRIE conditions.

The goat domestication process inferred from large-scale mitochondrial DNA analysis of wild and domestic individuals

PubMed Central

Naderi, Saeid; Rezaei, Hamid-Reza; Pompanon, François; Blum, Michael G. B.; Negrini, Riccardo; Naghash, Hamid-Reza; Balkız, Özge; Mashkour, Marjan; Gaggiotti, Oscar E.; Ajmone-Marsan, Paolo; Kence, Aykut; Vigne, Jean-Denis; Taberlet, Pierre

2008-01-01

The emergence of farming during the Neolithic transition, including the domestication of livestock, was a critical point in the evolution of human kind. The goat (Capra hircus) was one of the first domesticated ungulates. In this study, we compared the genetic diversity of domestic goats to that of the modern representatives of their wild ancestor, the bezoar, by analyzing 473 samples collected over the whole distribution range of the latter species. This partly confirms and significantly clarifies the goat domestication scenario already proposed by archaeological evidence. All of the mitochondrial DNA haplogroups found in current domestic goats have also been found in the bezoar. The geographic distribution of these haplogroups in the wild ancestor allowed the localization of the main domestication centers. We found no haplotype that could have been domesticated in the eastern half of the Iranian Plateau, nor further to the east. A signature of population expansion in bezoars of the C haplogroup suggests an early domestication center on the Central Iranian Plateau (Yazd and Kerman Provinces) and in the Southern Zagros (Fars Province), possibly corresponding to the management of wild flocks. However, the contribution of this center to the current domestic goat population is rather low (1.4%). We also found a second domestication center covering a large area in Eastern Anatolia, and possibly in Northern and Central Zagros. This last domestication center is the likely origin of almost all domestic goats today. This finding is consistent with archaeological data identifying Eastern Anatolia as an important domestication center. PMID:19004765

Non-Gaussian shape discrimination with spectroscopic galaxy surveys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Byun, Joyce; Bean, Rachel, E-mail: byun@astro.cornell.edu, E-mail: rbean@astro.cornell.edu

2015-03-01

We consider how galaxy clustering data, from Mpc to Gpc scales, from upcoming large scale structure surveys, such as Euclid and DESI, can provide discriminating information about the bispectrum shape arising from a variety of inflationary scenarios. Through exploring in detail the weighting of shape properties in the calculation of the halo bias and halo mass function we show how they probe a broad range of configurations, beyond those in the squeezed limit, that can help distinguish between shapes with similar large scale bias behaviors. We assess the impact, on constraints for a diverse set of non-Gaussian shapes, of galaxymore » clustering information in the mildly non-linear regime, and surveys that span multiple redshifts and employ different galactic tracers of the dark matter distribution. Fisher forecasts are presented for a Euclid-like spectroscopic survey of Hα-selected emission line galaxies (ELGs), and a DESI-like survey, of luminous red galaxies (LRGs) and [O-II] doublet-selected ELGs, in combination with Planck-like CMB temperature and polarization data.While ELG samples provide better probes of shapes that are divergent in the squeezed limit, LRG constraints, centered below z<1, yield stronger constraints on shapes with scale-independent large-scale halo biases, such as the equilateral template. The ELG and LRG samples provide complementary degeneracy directions for distinguishing between different shapes. For Hα-selected galaxies, we note that recent revisions of the expected Hα luminosity function reduce the halo bias constraints on the local shape, relative to the CMB. For galaxy clustering constraints to be comparable to those from the CMB, additional information about the Gaussian galaxy bias is needed, such as can be determined from the galaxy clustering bispectrum or probing the halo power spectrum directly through weak lensing. If the Gaussian galaxy bias is constrained to better than a percent level then the LSS and CMB data could provide complementary constraints that will enable differentiation of bispectrum with distinct theoretical origins but with similar large scale, squeezed-limit properties.« less

High-Throughput Microbore UPLC-MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies.

PubMed

Gray, Nicola; Lewis, Matthew R; Plumb, Robert S; Wilson, Ian D; Nicholson, Jeremy K

2015-06-05

A new generation of metabolic phenotyping centers are being created to meet the increasing demands of personalized healthcare, and this has resulted in a major requirement for economical, high-throughput metabonomic analysis by liquid chromatography-mass spectrometry (LC-MS). Meeting these new demands represents an emerging bioanalytical problem that must be solved if metabolic phenotyping is to be successfully applied to large clinical and epidemiological sample sets. Ultraperformance (UP)LC-MS-based metabolic phenotyping, based on 2.1 mm i.d. LC columns, enables comprehensive metabolic phenotyping but, when employed for the analysis of thousands of samples, results in high solvent usage. The use of UPLC-MS employing 1 mm i.d. columns for metabolic phenotyping rather than the conventional 2.1 mm i.d. methodology shows that the resulting optimized microbore method provided equivalent or superior performance in terms of peak capacity, sensitivity, and robustness. On average, we also observed, when using the microbore scale separation, an increase in response of 2-3 fold over that obtained with the standard 2.1 mm scale method. When applied to the analysis of human urine, the 1 mm scale method showed no decline in performance over the course of 1000 analyses, illustrating that microbore UPLC-MS represents a viable alternative to conventional 2.1 mm i.d. formats for routine large-scale metabolic profiling studies while also resulting in a 75% reduction in solvent usage. The modest increase in sensitivity provided by this methodology also offers the potential to either reduce sample consumption or increase the number of metabolite features detected with confidence due to the increased signal-to-noise ratios obtained. Implementation of this miniaturized UPLC-MS method of metabolic phenotyping results in clear analytical, economic, and environmental benefits for large-scale metabolic profiling studies with similar or improved analytical performance compared to conventional UPLC-MS.

The Space Operations Simulation Center (SOSC) and Closed-loop Hardware Testing for Orion Rendezvous System Design

NASA Technical Reports Server (NTRS)

D'Souza, Christopher; Milenkovich, Zoran; Wilson, Zachary; Huich, David; Bendle, John; Kibler, Angela

2011-01-01

The Space Operations Simulation Center (SOSC) at the Lockheed Martin (LM) Waterton Campus in Littleton, Colorado is a dynamic test environment focused on Autonomous Rendezvous and Docking (AR&D) development testing and risk reduction activities. The SOSC supports multiple program pursuits and accommodates testing Guidance, Navigation, and Control (GN&C) algorithms for relative navigation, hardware testing and characterization, as well as software and test process development. The SOSC consists of a high bay (60 meters long by 15.2 meters wide by 15.2 meters tall) with dual six degree-of-freedom (6DOF) motion simulators and a single fixed base 6DOF robot. The large testing area (maximum sensor-to-target effective range of 60 meters) allows for large-scale, flight-like simulations of proximity maneuvers and docking events. The facility also has two apertures for access to external extended-range outdoor target test operations. In addition, the facility contains four Mission Operations Centers (MOCs) with connectivity to dual high bay control rooms and a data/video interface room. The high bay is rated at Class 300,000 (. 0.5 m maximum particles/m3) cleanliness and includes orbital lighting simulation capabilities.

Virtual Network Configuration Management System for Data Center Operations and Management

NASA Astrophysics Data System (ADS)

Okita, Hideki; Yoshizawa, Masahiro; Uehara, Keitaro; Mizuno, Kazuhiko; Tarui, Toshiaki; Naono, Ken

Virtualization technologies are widely deployed in data centers to improve system utilization. However, they increase the workload for operators, who have to manage the structure of virtual networks in data centers. A virtual-network management system which automates the integration of the configurations of the virtual networks is provided. The proposed system collects the configurations from server virtualization platforms and VLAN-supported switches, and integrates these configurations according to a newly developed XML-based management information model for virtual-network configurations. Preliminary evaluations show that the proposed system helps operators by reducing the time to acquire the configurations from devices and correct the inconsistency of operators' configuration management database by about 40 percent. Further, they also show that the proposed system has excellent scalability; the system takes less than 20 minutes to acquire the virtual-network configurations from a large scale network that includes 300 virtual machines. These results imply that the proposed system is effective for improving the configuration management process for virtual networks in data centers.

Lewis Research Center R and D Facilities

NASA Technical Reports Server (NTRS)

1991-01-01

The NASA Lewis Research Center (LeRC) defines and develops advanced technology for high priority national needs. The work of the Center is directed toward new propulsion, power, and communications technologies for application to aeronautics and space, so that U.S. leadership in these areas is ensured. The end product is knowledge, usually in a report, that is made fully available to potential users--the aircraft engine industry, the energy industry, the automotive industry, the space industry, and other NASA centers. In addition to offices and laboratories for almost every kind of physical research in such fields as fluid mechanics, physics, materials, fuels, combustion, thermodynamics, lubrication, heat transfer, and electronics, LeRC has a variety of engineering test cells for experiments with components such as compressors, pumps, conductors, turbines, nozzles, and controls. A number of large facilities can simulate the operating environment for a complete system: altitude chambers for aircraft engines; large supersonic wind tunnels for advanced airframes and propulsion systems; space simulation chambers for electric rockets or spacecraft; and a 420-foot-deep zero-gravity facility for microgravity experiments. Some problems are amenable to detection and solution only in the complete system and at essentially full scale. By combining basic research in pertinent disciplines and generic technologies with applied research on components and complete systems, LeRC has become one of the most productive centers in its field in the world. This brochure describes a number of the facilities that provide LeRC with its exceptional capabilities.

Extraterrestrial resource utilization for economy in space missions

NASA Technical Reports Server (NTRS)

Lewis, J. S.; Ramohalli, K.; Triffet, T.

1990-01-01

The NASA/University of Arizona Space Engineering Research Center is dedicated to research on the discovery, characterization, mapping, beneficiation, extraction, processing, and fabrication of useful products from extraterrestrial material. Schemes for the automated production of low-technology products that are likely to be desired in large quantities in the early stages of any large-scale space activity are identified and developed. This paper summarizes the research program, concentrating upon the production of (1) propellants, both cryogenic and storable, (2) volatiles such as water, nitrogen, and carbon dioxide for use in life-support systems (3) structural metals, and (4) refractories for use in aerobrakes and furnace linings.

Fermi Gamma-Ray Space Telescope Science Overview

NASA Technical Reports Server (NTRS)

Thompson, David J.

2010-01-01

After more than 2 years of science operations, the Fermi Gamma-ray Space Telescope continues to survey the high-energy sky on a daily basis. In addition to the more than 1400 sources found in the first Fermi Large Area Telescope Catalog (I FGL), new results continue to emerge. Some of these are: (1) Large-scale diffuse emission suggests possible activity from the Galactic Center region in the past; (2) a gamma-ray nova was found, indicating particle acceleration in this binary system; and (3) the Crab Nebula, long thought to be a steady source, has varied in the energy ranges seen by both Fermi instruments.

A new large area scintillator screen for X-ray imaging

NASA Astrophysics Data System (ADS)

Nagarkar, V. V.; Miller, S. R.; Tipnis, S. V.; Lempicki, A.; Brecher, C.; Lingertat, H.

2004-01-01

We report on the development of a new, large area, powdered scintillator screen based on Lu 2O 3(Eu). As reported earlier, the transparent ceramic form of this material has a very high density of 9.4 g/cm 3, a high light output comparable to that of CsI(Tl), and emits in a narrow spectral band centered at about 610 nm. Research into fabrication of this ceramic scintillator in a large area format is currently underway, however the process is not yet practical for large scale production. Here we have explored fabrication of large area screens using precursor powders from which the ceramics are fabricated. To date we have produced up to 16 × 16 cm 2 area screens with thickness in the range of 18 mg/cm 2. This paper outlines the screen fabrication technique and presents its imaging performance in comparison with a commercial Gd 2O 2S:Tb (GOS) screen.

Impact of SCALE-UP on science teaching self-efficacy of students in general education science courses

NASA Astrophysics Data System (ADS)

Cassani, Mary Kay Kuhr

The objective of this study was to evaluate the effect of two pedagogical models used in general education science on non-majors' science teaching self-efficacy. Science teaching self-efficacy can be influenced by inquiry and cooperative learning, through cognitive mechanisms described by Bandura (1997). The Student Centered Activities for Large Enrollment Undergraduate Programs (SCALE-UP) model of inquiry and cooperative learning incorporates cooperative learning and inquiry-guided learning in large enrollment combined lecture-laboratory classes (Oliver-Hoyo & Beichner, 2004). SCALE-UP was adopted by a small but rapidly growing public university in the southeastern United States in three undergraduate, general education science courses for non-science majors in the Fall 2006 and Spring 2007 semesters. Students in these courses were compared with students in three other general education science courses for non-science majors taught with the standard teaching model at the host university. The standard model combines lecture and laboratory in the same course, with smaller enrollments and utilizes cooperative learning. Science teaching self-efficacy was measured using the Science Teaching Efficacy Belief Instrument - B (STEBI-B; Bleicher, 2004). A science teaching self-efficacy score was computed from the Personal Science Teaching Efficacy (PTSE) factor of the instrument. Using non-parametric statistics, no significant difference was found between teaching models, between genders, within models, among instructors, or among courses. The number of previous science courses was significantly correlated with PTSE score. Student responses to open-ended questions indicated that students felt the larger enrollment in the SCALE-UP room reduced individual teacher attention but that the large round SCALE-UP tables promoted group interaction. Students responded positively to cooperative and hands-on activities, and would encourage inclusion of more such activities in all of the courses. The large enrollment SCALE-UP model as implemented at the host university did not increase science teaching self-efficacy of non-science majors, as hypothesized. This was likely due to limited modification of standard cooperative activities according to the inquiry-guided SCALE-UP model. It was also found that larger SCALE-UP enrollments did not decrease science teaching self-efficacy when standard cooperative activities were used in the larger class.

Design of a decentralized reusable research database architecture to support data acquisition in large research projects.

PubMed

Iavindrasana, Jimison; Depeursinge, Adrien; Ruch, Patrick; Spahni, Stéphane; Geissbuhler, Antoine; Müller, Henning

2007-01-01

The diagnostic and therapeutic processes, as well as the development of new treatments, are hindered by the fragmentation of information which underlies them. In a multi-institutional research study database, the clinical information system (CIS) contains the primary data input. An important part of the money of large scale clinical studies is often paid for data creation and maintenance. The objective of this work is to design a decentralized, scalable, reusable database architecture with lower maintenance costs for managing and integrating distributed heterogeneous data required as basis for a large-scale research project. Technical and legal aspects are taken into account based on various use case scenarios. The architecture contains 4 layers: data storage and access are decentralized at their production source, a connector as a proxy between the CIS and the external world, an information mediator as a data access point and the client side. The proposed design will be implemented inside six clinical centers participating in the @neurIST project as part of a larger system on data integration and reuse for aneurism treatment.

A prototype automatic phase compensation module

NASA Technical Reports Server (NTRS)

Terry, John D.

1992-01-01

The growing demands for high gain and accurate satellite communication systems will necessitate the utilization of large reflector systems. One area of concern of reflector based satellite communication is large scale surface deformations due to thermal effects. These distortions, when present, can degrade the performance of the reflector system appreciable. This performance degradation is manifested by a decrease in peak gain, and increase in sidelobe level, and pointing errors. It is essential to compensate for these distortion effects and to maintain the required system performance in the operating space environment. For this reason the development of a technique to offset the degradation effects is highly desirable. Currently, most research is direct at developing better material for the reflector. These materials have a lower coefficient of linear expansion thereby reducing the surface errors. Alternatively, one can minimize the distortion effects of these large scale errors by adaptive phased array compensation. Adaptive phased array techniques have been studied extensively at NASA and elsewhere. Presented in this paper is a prototype automatic phase compensation module designed and built at NASA Lewis Research Center which is the first stage of development for an adaptive array compensation module.

The Large-Scale Cosmic-Ray Anisotropy as Observed with Milagro

NASA Astrophysics Data System (ADS)

Abdo, A. A.; Allen, B. T.; Aune, T.; Berley, D.; Casanova, S.; Chen, C.; Dingus, B. L.; Ellsworth, R. W.; Fleysher, L.; Fleysher, R.; Gonzalez, M. M.; Goodman, J. A.; Hoffman, C. M.; Hopper, B.; Hüntemeyer, P. H.; Kolterman, B. E.; Lansdell, C. P.; Linnemann, J. T.; McEnery, J. E.; Mincer, A. I.; Nemethy, P.; Noyes, D.; Pretz, J.; Ryan, J. M.; Parkinson, P. M. Saz; Shoup, A.; Sinnis, G.; Smith, A. J.; Sullivan, G. W.; Vasileiou, V.; Walker, G. P.; Williams, D. A.; Yodh, G. B.

2009-06-01

Results are presented of a harmonic analysis of the large-scale cosmic-ray (CR) anisotropy as observed by the Milagro observatory. We show a two-dimensional display of the sidereal anisotropy projections in right ascension (R.A.) generated by the fitting of three harmonics to 18 separate declination bands. The Milagro observatory is a water Cherenkov detector located in the Jemez mountains near Los Alamos, New Mexico. With a high duty cycle and large field of view, Milagro is an excellent instrument for measuring this anisotropy with high sensitivity at TeV energies. The analysis is conducted using a seven-year data sample consisting of more than 95 billion events, the largest such data set in existence. We observe an anisotropy with a magnitude around 0.1% for CRs with a median energy of 6 TeV. The dominant feature is a deficit region of depth (2.49 ± 0.02 stat. ± 0.09 sys.) ×10-3 in the direction of the Galactic north pole centered at 189 deg R.A. We observe a steady increase in the magnitude of the signal over seven years.

KSC-2011-8246

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida negotiates the turn from Kennedy Parkway onto Schwartz Road on its way toward NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The 525-foot-tall Vehicle Assembly Building peeps over the treetops, at right. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8247

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida travels along Schwartz Road on its way toward NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The Assembly and Refurbishment Facility, formerly used to process components of space shuttle solid rocket boosters, is in the background at right. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

KSC-2011-8227

NASA Image and Video Library

2011-12-11

CAPE CANAVERAL, Fla. – The transporter carrying the high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida makes a wide turn into the right-hand lane of the NASA Causeway as it leaves the visitor complex on its way to NASA Kennedy Space Center's Launch Complex 39 turn basin. It is standard procedure for large payloads and equipment to travel against the normal flow of traffic under the supervision of a move crew when being transported on or off center property. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

Luminosity measurements for the R scan experiment at BESIII

NASA Astrophysics Data System (ADS)

Ablikim, M.; Achasov, M. N.; Ahmed, S.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Bakina, O.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, S.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Farinelli, R.; Fava, L.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, R. P.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Z. L.; Hussain, T.; Ikegami Andersson, W.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Leithoff, H.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Y. B.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Y. Y.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Musiol, P.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, W.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xie, Y. H.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. N.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

2017-06-01

By analyzing the large-angle Bhabha scattering events e+e- → (γ)e+e- and diphoton events e+e- → (γ)γγ for the data sets collected at center-of-mass (c.m.) energies between 2.2324 and 4.5900 GeV (131 energy points in total) with the upgraded Beijing Spectrometer (BESIII) at the Beijing Electron-Positron Collider (BEPCII), the integrated luminosities have been measured at the different c.m. energies, individually. The results are important inputs for the R value and J/ψ resonance parameter measurements. Supported by National Key Basic Research Program of China (2015CB856700), National Natural Science Foundation of China (NSFC) (10935007, 11121092, 11125525, 11235011, 11322544, 11335008, 11375170, 11275189, 11079030, 11475164, 11475169, 11005109, 10979095, 11275211), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program; Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (11179007, U1232201, U1332201, U1532102). (KJCX2-YW-N29, KJCX2-YW-N45). 100 Talents Program of CAS, INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy, Ministry of Development of Turkey (DPT2006K-120470), Russian Foundation for Basic Research (14-07-91152), U. S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt, WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0)

Effect of turning frequency on co-composting pig manure and fungus residue.

PubMed

Jiang-Ming, Zhou

2017-03-01

Composting of agricultural wastes not only can reduce environmental pollution caused by improper disposal, but also can recycle agricultural wastes and transform them into highly valuable products, such as fertilizers or soil conditioners, for agricultural applications. However, the composting process and final product are easily affected by the limited oxygen supply that results from insufficient aeration, especially in the center of a large-scale windrow. Hence, a pilot-scale experiment was conducted to investigate the effects of the turning frequency on the composting efficiency and compost quality of used pig manure and fungus residue. Physical and chemical characteristics were measured over the course of 63 days of composting. The data indicate that higher temperatures and more rapid moisture removal generally result from a turning treatment of once every 2-4 days than in fewer, or no, turning treatments. The total nitrogen, total phosphorus, and total potassium contents increased in all windrows as the organic matter content decreased, but both the increases and decrease were greater in windrows that were turned more frequently. The reduction of the organic matter mass by 53.7-66.0% for a turning of once every 2-8 days is significantly higher than that for the static windrow (39.1%). Although there is an increase in nitrogen mass loss with an increased turning frequency, lower nitrogen mass losses (12.7-25.7%) in all treatments were noted compared with previous studies. A final compost product with less moisture, less weight, higher nutrient content (N, P, and K), and greater stability was obtained in windrows with turning frequencies of once every 2-4 days, which is recommended when composting pig manure and fungus residue. Composting of agricultural wastes not only can reduce environmental pollution caused by improper disposal, but recycling of agricultural wastes transforms them into highly valuable products, such as fertilizers or soil conditioners, for agricultural applications. However, the composting process and final product are easily affected by the limited oxygen supply that results from insufficient aeration, especially in the center of a large-scale windrow. Hence, a pilot-scale experiment was conducted to investigate the effects of the turning frequency on the composting efficiency and compost quality of used pig manure and fungus residue, so as to capture an operational technique suitable for the effective co-composting pig manure and edible fungi residue for a large-scale composting plant.

Consistency of clinical biomechanical measures between three different institutions: implications for multi-center biomechanical and epidemiological research.

PubMed

Myer, Gregory D; Wordeman, Samuel C; Sugimoto, Dai; Bates, Nathaniel A; Roewer, Benjamin D; Medina McKeon, Jennifer M; DiCesare, Christopher A; Di Stasi, Stephanie L; Barber Foss, Kim D; Thomas, Staci M; Hewett, Timothy E

2014-05-01

Multi-center collaborations provide a powerful alternative to overcome the inherent limitations to single-center investigations. Specifically, multi-center projects can support large-scale prospective, longitudinal studies that investigate relatively uncommon outcomes, such as anterior cruciate ligament injury. This project was conceived to assess within- and between-center reliability of an affordable, clinical nomogram utilizing two-dimensional video methods to screen for risk of knee injury. The authors hypothesized that the two-dimensional screening methods would provide good-to-excellent reliability within and between institutions for assessment of frontal and sagittal plane biomechanics. Nineteen female, high school athletes participated. Two-dimensional video kinematics of the lower extremity during a drop vertical jump task were collected on all 19 study participants at each of the three facilities. Within-center and between-center reliability were assessed with intra- and inter-class correlation coefficients. Within-center reliability of the clinical nomogram variables was consistently excellent, but between-center reliability was fair-to-good. Within-center intra-class correlation coefficient for all nomogram variables combined was 0.98, while combined between-center inter-class correlation coefficient was 0.63. Injury risk screening protocols were reliable within and repeatable between centers. These results demonstrate the feasibility of multi-site biomechanical studies and establish a framework for further dissemination of injury risk screening algorithms. Specifically, multi-center studies may allow for further validation and optimization of two-dimensional video screening tools. 2b.

On the relationship between water vapor over the oceans and sea surface temperature

NASA Technical Reports Server (NTRS)

Stephens, Graeme L.

1990-01-01

Monthly mean precipitable water data obtained from passive microwave radiometry were correlated with the National Meteorological Center (NMC) blended sea surface temperature data. It is shown that the monthly mean water vapor content of the atmosphere above the oceans can generally be prescribed from the sea surface temperature with a standard deviation of 0.36 g/sq cm. The form of the relationship between precipitable water and sea surface temperature in the range T (sub s) greater than 18 C also resembles that predicted from simple arguments based on the Clausius-Clapeyron relationship. The annual cycle of the globally integrated mass of Scanning Multichannel Microwave Radiometer (SMMR) water vapor is shown to differ from analyses of other water vapor data in both phase and amplitude and these differences point to a significant influence of the continents on water vapor. Regional scale analyses of water vapor demonstrate that monthly averaged water vapor data, when contrasted with the bulk sea surface temperature relationship developed in this study, reflect various known characteristics of the time mean large-scale circulation over the oceans. A water vapor parameter is introduced to highlight the effects of large-scale motion on atmospheric water vapor. Based on the magnitude of this parameter, it is shown that the effects of large-scale flow on precipitable water vapor are regionally dependent, but for the most part, the influence of circulation is generally less than about + or - 20 percent of the seasonal mean.

On the relationship between water vapor over the oceans and sea surface temperature

NASA Technical Reports Server (NTRS)

Stephens, Graeme L.

1989-01-01

Monthly mean precipitable water data obtained from passive microwave radiometry were correlated with the National Meteorological Center (NMC) blended sea surface temperature data. It is shown that the monthly mean water vapor content of the atmosphere above the oceans can generally be prescribed from the sea surface temperature with a standard deviation of 0.36 g/sq cm. The form of the relationship between precipitable water and sea surface temperature in the range T(sub s) greater than 18 C also resembles that predicted from simple arguments based on the Clausius-Clapeyron relationship. The annual cycle of the globally integrated mass of Scanning Multichannel Microwave Radiometer (SMMR) water vapor is shown to differ from analyses of other water vapor data in both phase and amplitude and these differences point to a significant influence of the continents on water vapor. Regional scale analyses of water vapor demonstrate that monthly averaged water vapor data, when contrasted with the bulk sea surface temperature relationship developed in this study, reflect various known characteristics of the time mean large-scale circulation over the oceans. A water vapor parameter is introduced to highlight the effects of large-scale motion on atmospheric water vapor. Based on the magnitude of this parameter, it is shown that the effects of large-scale flow on precipitable water vapor are regionally dependent, but for the most part, the influence of circulation is generally less than about + or - 20 percent of the seasonal mean.

Large Magneto-ionic Variations toward the Galactic Center Magnetar, PSR J1745-2900

NASA Astrophysics Data System (ADS)

Desvignes, G.; Eatough, R. P.; Pen, U. L.; Lee, K. J.; Mao, S. A.; Karuppusamy, R.; Schnitzeler, D. H. F. M.; Falcke, H.; Kramer, M.; Wucknitz, O.; Spitler, L. G.; Torne, P.; Liu, K.; Bower, G. C.; Cognard, I.; Lyne, A. G.; Stappers, B. W.

2018-01-01

Polarized radio emission from PSR J1745‑2900 has already been used to investigate the strength of the magnetic field in the Galactic center (GC), close to Sagittarius A*. Here we report how persistent radio emission from this magnetar, for over four years since its discovery, has revealed large changes in the observed Faraday rotation measure (RM), by up to 3500 rad m‑2 (a 5% fractional change). From simultaneous analysis of the dispersion measure, we determine that these fluctuations are dominated by variations in either the projected magnetic field or the free electron content within the GC, along the changing line of sight to the rapidly moving magnetar. From a structure function analysis of RM variations, and a recent epoch of rapid change of RM, we determine a minimum scale of magneto-ionic fluctuations of size ∼2 au at the GC distance, inferring PSR J1745‑2900 is just ∼0.1 pc behind an additional scattering screen.

Replacement of Hydrochlorofluorocarbon (HCFC) -225 Solvent for Cleaning and Verification Sampling of NASA Propulsion Oxygen Systems Hardware, Ground Support Equipment, and Associated Test Systems

NASA Technical Reports Server (NTRS)

Burns, H. D.; Mitchell, M. A.; McMillian, J. H.; Farner, B. R.; Harper, S. A.; Peralta, S. F.; Lowrey, N. M.; Ross, H. R.; Juarez, A.

2015-01-01

Since the 1990's, NASA's rocket propulsion test facilities at Marshall Space Flight Center (MSFC) and Stennis Space Center (SSC) have used hydrochlorofluorocarbon-225 (HCFC-225), a Class II ozone-depleting substance, to safety clean and verify the cleanliness of large scale propulsion oxygen systems and associated test facilities. In 2012 through 2014, test laboratories at MSFC, SSC, and Johnson Space Center-White Sands Test Facility collaborated to seek out, test, and qualify an environmentally preferred replacement for HCFC-225. Candidate solvents were selected, a test plan was developed, and the products were tested for materials compatibility, oxygen compatibility, cleaning effectiveness, and suitability for use in cleanliness verification and field cleaning operations. Honewell Soltice (TradeMark) Performance Fluid (trans-1-chloro-3,3, 3-trifluoropropene) was selected to replace HCFC-225 at NASA's MSFC and SSC rocket propulsion test facilities.

Organizational factors and office workers' health after the World Trade Center terrorist attacks: long-term physical symptoms, psychological distress, and work productivity.

PubMed

Osinubi, Omowunmi Y O; Gandhi, Sampada K; Ohman-Strickland, Pamela; Boglarsky, Cheryl; Fiedler, Nancy; Kipen, Howard; Robson, Mark

2008-02-01

To assess if organizational factors are predictors of workers' health and productivity after the World Trade Center attacks. We conducted a survey of 750 workers and compared those who had direct exposures to the World Trade Center attacks (south of Canal Street workers; primary victims) with those less directly exposed (north of Canal Street workers; other victims and non-victims). South of Canal Street workers reported headache more frequently than north of Canal Street workers did (P = 0.0202). Primary victims reported headache and cough more frequently than did other victims and non-victims (P = 0.0086 and 0.0043, respectively). Defensive organizational culture was an independent predictor of cough and job stress, and job stress was an independent predictor of on-the-job productivity losses. Organizational variables may modify health and productivity outcomes after a large-scale traumatic event in the workplace.

The influence of sea surface temperature anomalies on low-frequency variability of the North Atlantic Oscillation

NASA Astrophysics Data System (ADS)

Manganello, Julia V.

2008-05-01

The influence of sea surface temperature anomalies (SSTA) on multi-year persistence of the North Atlantic Oscillation (NAO) during the second half of the twentieth century is investigated using the Center for Ocean-Land-Atmosphere Studies (COLA) Atmospheric GCM (AGCM) with an emphasis on isolating the geographic location of the SSTA that produce this influence. The present study focuses on calculating the atmospheric response to the SSTA averaged over 1988 1995 (1961 1968) corresponding to the observed period of strong persistence of the positive (negative) phase of the decadal NAO. The model response to the global 1988 1995 average SSTA shows a statistically significant large-scale pattern characteristic of the positive phase of the NAO. Forcing with the global 1961 1968 average SSTA generates a NAO of the opposite polarity compared to observations. However, all large-scale features both in the model and observations during this period are weaker in magnitude and less significant compared to 1988 1995. Additional idealized experiments show that over the northern center of the NAO the non-linear component of the forced response appears to be quite important and acts to enhance the positive NAO signal. On the other hand, over the southern center where the model response is the strongest, it is also essentially linear. The 1988 1995 average SSTA restricted to the western tropical Pacific region produce a positive NAO remarkably similar in structure but stronger in magnitude than the model response to the global and tropical Indo-Pacific 1988 1995 forcing. A 200-hPa geopotential height response in these experiments shows a positive anomaly over the southern center of the NAO embedded in the Rossby wave trains propagating from the western tropical Pacific. Indian Ocean SSTA lead to much weaker positive NAO primarily through the effect on its northern center. SST forcing confined to the North Atlantic north of equator does not produce a response statistically different from the control simulation, suggesting that it is not strong enough to significantly affect the phase of the decadal NAO. Inclusion of the South Atlantic north of 45° south does not change this result.

Cross-cultural adaptation of the German version of the spinal stenosis measure.

PubMed

Wertli, Maria M; Steurer, Johann; Wildi, Lukas M; Held, Ulrike

2014-06-01

To validate the German version of the spinal stenosis measure (SSM), a disease-specific questionnaire assessing symptom severity, physical function, and satisfaction with treatment in patients with lumbar spinal stenosis. After translation, cross-cultural adaptation, and pilot testing, we assessed internal consistency, test-retest reliability, construct validity, and responsiveness of the SSM subscales. Data from a large Swiss multi-center prospective cohort study were used. Reference scales for the assessment of construct validity and responsiveness were the numeric rating scale, pain thermometer, and the Roland Morris Disability Questionnaire. One hundred and eight consecutive patients were included in this validation study, recruited from five different centers. Cronbach's alpha was above 0.8 for all three subscales of the SSM. The objectivity of the SSM was assessed using a partial credit approach. The model showed a good global fit to the data. Of the 108 patients 78 participated in the test-retest procedure. The ICC values were above 0.8 for all three subscales of the SSM. Correlations with reference scales were above 0.7 for the symptom and function subscales. For satisfaction subscale, it was 0.66 or above. Clinically meaningful changes of the reference scales over time were associated with significantly more improvement in all three SSM subscales (p < 0.001). Conclusion: The proposed version of the SSM showed very good measurement properties and can be considered validated for use in the German language.

Diversity in the representation of large-scale circulation associated with ENSO-Indian summer monsoon teleconnections in CMIP5 models

NASA Astrophysics Data System (ADS)

Ramu, Dandi A.; Chowdary, Jasti S.; Ramakrishna, S. S. V. S.; Kumar, O. S. R. U. B.

2018-04-01

Realistic simulation of large-scale circulation patterns associated with El Niño-Southern Oscillation (ENSO) is vital in coupled models in order to represent teleconnections to different regions of globe. The diversity in representing large-scale circulation patterns associated with ENSO-Indian summer monsoon (ISM) teleconnections in 23 Coupled Model Intercomparison Project Phase 5 (CMIP5) models is examined. CMIP5 models have been classified into three groups based on the correlation between Niño3.4 sea surface temperature (SST) index and ISM rainfall anomalies, models in group 1 (G1) overestimated El Niño-ISM teleconections and group 3 (G3) models underestimated it, whereas these teleconnections are better represented in group 2 (G2) models. Results show that in G1 models, El Niño-induced Tropical Indian Ocean (TIO) SST anomalies are not well represented. Anomalous low-level anticyclonic circulation anomalies over the southeastern TIO and western subtropical northwest Pacific (WSNP) cyclonic circulation are shifted too far west to 60° E and 120° E, respectively. This bias in circulation patterns implies dry wind advection from extratropics/midlatitudes to Indian subcontinent. In addition to this, large-scale upper level convergence together with lower level divergence over ISM region corresponding to El Niño are stronger in G1 models than in observations. Thus, unrealistic shift in low-level circulation centers corroborated by upper level circulation changes are responsible for overestimation of ENSO-ISM teleconnections in G1 models. Warm Pacific SST anomalies associated with El Niño are shifted too far west in many G3 models unlike in the observations. Further large-scale circulation anomalies over the Pacific and ISM region are misrepresented during El Niño years in G3 models. Too strong upper-level convergence away from Indian subcontinent and too weak WSNP cyclonic circulation are prominent in most of G3 models in which ENSO-ISM teleconnections are underestimated. On the other hand, many G2 models are able to represent most of large-scale circulation over Indo-Pacific region associated with El Niño and hence provide more realistic ENSO-ISM teleconnections. Therefore, this study advocates the importance of representation/simulation of large-scale circulation patterns during El Niño years in coupled models in order to capture El Niño-monsoon teleconnections well.

Multigrid calculation of three-dimensional viscous cascade flows

NASA Technical Reports Server (NTRS)

Arnone, A.; Liou, M.-S.; Povinelli, L. A.

1991-01-01

A 3-D code for viscous cascade flow prediction was developed. The space discretization uses a cell-centered scheme with eigenvalue scaling to weigh the artificial dissipation terms. Computational efficiency of a four stage Runge-Kutta scheme is enhanced by using variable coefficients, implicit residual smoothing, and a full multigrid method. The Baldwin-Lomax eddy viscosity model is used for turbulence closure. A zonal, nonperiodic grid is used to minimize mesh distortion in and downstream of the throat region. Applications are presented for an annular vane with and without end wall contouring, and for a large scale linear cascade. The calculation is validated by comparing with experiments and by studying grid dependency.

Improving Large-Scale Testing Capability by Modifying the 40- by 80-ft Wind Tunnel

NASA Technical Reports Server (NTRS)

Mort, Kenneth W.; Soderman, Paul T.; Eckert, William T.

1979-01-01

Interagency studies conducted during the last several years have indicated the need to Improve full-scale testing capabilities. The studies showed that the most effective trade between test capability and facility cost was provided by re-powering the existing Ames Research Center 40- by 80-ft Wind Tunnel to Increase the maximum speed from about 100 m/s (200 knots) lo about 150 m/s (300 knots) and by adding a new 24- by 37-m (80- by 120-ft) test section powered for about a 50-m/s (100-knot) maximum speed. This paper reviews the design of the facility, a few or its capabilities, and some of its unique features.

Conference Summary

NASA Technical Reports Server (NTRS)

Begelman, Mitchell C.

1997-01-01

At the end of three days' spirited discussion of the type 2 Seyfert galaxy NGC 1068, what do we think we understand about this object? New observations, particularly in the infrared and radio are helping to resolve old problems, while drawing attention to new ones. It appears that NGC 1068 is a relatively normal spiral galaxy in which large-scale gravitational disturbances are funneling matter into the nucleus. A collimated outflow disturbs the interstellar medium out to kiloparsec scales, but the nucleus itself is hidden behind an opaque screen. Radio observations have now pierced the screen, and suggest that at the center of it all, a 10-20 million solar mass black hole is accreting at close to its Eddington limit.

Multigrid calculation of three-dimensional viscous cascade flows

NASA Technical Reports Server (NTRS)

Arnone, A.; Liou, M.-S.; Povinelli, L. A.

1991-01-01

A three-dimensional code for viscous cascade flow prediction has been developed. The space discretization uses a cell-centered scheme with eigenvalue scaling to weigh the artificial dissipation terms. Computational efficiency of a four-stage Runge-Kutta scheme is enhanced by using variable coefficients, implicit residual smoothing, and a full-multigrid method. The Baldwin-Lomax eddy-viscosity model is used for turbulence closure. A zonal, nonperiodic grid is used to minimize mesh distortion in and downstream of the throat region. Applications are presented for an annular vane with and without end wall contouring, and for a large-scale linear cascade. The calculation is validated by comparing with experiments and by studying grid dependency.

Robotic Manufacturing of 18-ft (5.5m) Diameter Cryogenic Fuel Tank Dome Assemblies for the NASA Ares I Rocket

NASA Technical Reports Server (NTRS)

Jones, Ronald E.; Carter, Robert W.

2012-01-01

The Ares I rocket was the first launch vehicle scheduled for manufacture under the National Aeronautic and Space Administration's Constellation program. A series of full-scale Ares I development articles were constructed on the Robotic Weld Tool at the NASA George C. Marshall Space Flight Center in Huntsville, Alabama. The Robotic Weld Tool is a 100 ton, 7- axis, robotic manufacturing system capable of machining and friction stir welding large-scale space hardware. This paper will focus on the friction stir welding of 18-ft (5.5m) diameter cryogenic fuel tank components; specifically, the liquid hydrogen forward dome and two common bulkhead manufacturing development articles.

Circumnuclear Structures in Megamaser Host Galaxies

NASA Astrophysics Data System (ADS)

Pjanka, Patryk; Greene, Jenny E.; Seth, Anil C.; Braatz, James A.; Henkel, Christian; Lo, Fred K. Y.; Läsker, Ronald

2017-08-01

Using the Hubble Space Telescope, we identify circumnuclear (100-500 pc scale) structures in nine new H2O megamaser host galaxies to understand the flow of matter from kpc-scale galactic structures down to the supermassive black holes (SMBHs) at galactic centers. We double the sample analyzed in a similar way by Greene et al. and consider the properties of the combined sample of 18 sources. We find that disk-like structure is virtually ubiquitous when we can resolve <200 pc scales, in support of the notion that non-axisymmetries on these scales are a necessary condition for SMBH fueling. We perform an analysis of the orientation of our identified nuclear regions and compare it with the orientation of megamaser disks and the kpc-scale disks of the hosts. We find marginal evidence that the disk-like nuclear structures show increasing misalignment from the kpc-scale host galaxy disk as the scale of the structure decreases. In turn, we find that the orientation of both the ˜100 pc scale nuclear structures and their host galaxy large-scale disks is consistent with random with respect to the orientation of their respective megamaser disks.

Biophysical Model of Cortical Network Activity and the Influence of Electrical Stimulation

DTIC Science & Technology

2015-11-13

dynamics of seizure propagation across micro domains in the vicinity of the seizure onset zone, Journal of Neural Engineering, (08 2015): 46016. doi...field potential (lfp) in a large scalesimulation of cerebral cortex , Society for Neuroscience. 19-OCT-15, . : , TOTAL: 2 Number of Peer-Reviewed...of graduating undergraduates who achieved a 3.5 GPA to 4.0 (4.0 max scale ): Number of graduating undergraduates funded by a DoD funded Center of

Conference on Fire Resistant Materials (FIREMEN): A compilation of presentations and papers

NASA Technical Reports Server (NTRS)

Kourtides, D. A. (Editor)

1978-01-01

The proceedings of the NASA Fire Resistant Materials Engineering (FIREMEN) Program held at Ames Research Center on April, 13, 14, 1978 are reported. The purpose of the conference was to discuss the results of NASA in the field of aircraft fire safety and fire resistant materials. The program components include the following: (1) large-scale testing; (2) fire toxicology; (3) polymeric materials; and (4) bibliography related and/or generated from the program.

Sub-daily sea ice motion and deformation from RADARSAT observations

NASA Technical Reports Server (NTRS)

Kwok, R.; Cunningham, G. F.

2003-01-01

We find a persistent level of oscillatory sea ice motion and deformation, superimposed on the large-scale wind-driven field, in May 2002 (spring) and February 2003 (mid-winter), in the high Arctic over a region centered at approx.(85degreeN, 135degreeW). At this latitude, the RADARSAT wide-swath SAR coverage provides 4??equential observations every day, for ice motion retrieval, with a sampling interval at the orbital period of approx. 101 minutes.

Experience in Organization of Urgent Medical Care in Large-Scale Accident Conditions at Nuclear Power Stations

DTIC Science & Technology

2001-05-01

approximately 340 Gwt) which is 17% of the worldwide electricity production level. The Chernobyl Nuclear Disaster with its long-term medico-biological...population to avoid or minimize the risk of their exposure. In October 1986, after the Chernobyl Nuclear Disaster the Federal Center of Radiation...period of their cooperation the Urgent Medical Care Department and the Rapid Response Teams visited the following sites of accidents: "* Chernobyl (a fire

Staff Development, Deception Operations, and Force Projection: Lessons from the Normandy Invasion

DTIC Science & Technology

2015-12-21

1940.8 The Allies needed to breach Germany’s Atlantic Wall and establish a lodgment and logistic center before large-scale ground operations could...invasion of Italy in 1943 — was the third allied amphibious operation in the North African, Mediterranean, and European Theatre . Between 1942 and 1943, the...Schuster 1948), 122-125. 18 Pogue, The Supreme Command, 45-48; Douglas Porch, The Mediterranean Theatre in World War II: The Path to Victory (New

Analysis of Stress Distributions Under Lightweight Wheeled Vehicles

DTIC Science & Technology

2013-10-09

For a balanced analysis it is important at examine the full scale error ε f . Sinkage error, although large in a relative sense is typically on the...director of the Edgerton Center at MIT, to Thuan Doan, and to Meccanotecnica Riesi SRL for collaborating on manufacturing the custom sensing array...a pulling/braking force at the vehicle axle. Fx = T −Rc (33) The importance of drawbar force is obvious, since a positive drawbar force implies that

Large-scale clustering of galaxies in the CfA Redshift Survey

NASA Technical Reports Server (NTRS)

Vogeley, Michael S.; Park, Changbom; Geller, Margaret J.; Huchra, John P.

1992-01-01

The power spectrum of the galaxy distribution in the Center for Astrophysics Redshift Survey (de Lapparent et al., 1986; Geller and Huchra, 1989; and Huchra et al., 1992) is measured up to wavelengths of 200/h Mpc. Results are compared with several cosmological simulations with Gaussian initial conditions. It is shown that the power spectrum of the standard CDM model is inconsistent with the observed power spectrum at the 99 percent confidence level.

What Works? Common Practices in High Functioning Afterschool Programs across the Nation in Math, Reading, Science, Arts, Technology, and Homework--A Study by the National Partnership. The Afterschool Program Assessment Guide. CRESST Report 768

ERIC Educational Resources Information Center

Huang, Denise; Cho, Jamie; Mostafavi, Sima; Nam, Hannah H.; Oh, Christine; Harven, Aletha; Leon, Seth

2010-01-01

In an effort to identify and incorporate exemplary practices into existing and future afterschool programs, the U.S. Department of Education commissioned a large-scale evaluation of the 21st Century Community Learning Center (CCLC) program. The purpose of this evaluation project was to develop resources and professional development that addresses…

Subsurface Fluxes Beneath Large-Scale Convective Centers in the Indian Ocean: Coupled Air-Wave-Sea Processes in the Subtropics

DTIC Science & Technology

2013-09-30

Figure 1 – Measurement systems installed on R/V Roger Revelle for DYNAMO /LASP. Inset map shows locations of land-based sounding stations...oceanographic moorings and the research vessels Mirai and Revelle during the intensive observation period of DYNAMO . The black line outlines the flight...under which each dominates. Transmission profile plus near-surface mixing measurements from LASP/ DYNAMO are being used to assess bounds on the

Evaluations of treatment efficacy of depression from perspective of both patients' symptoms and general sense of mental health and wellbeing: A large scale, multi-centered, longitudinal study in China.

PubMed

Zeng, Qingzhi; Wang, Wei Chun; Fang, Yiru; Mellor, David; Mccabe, Marita; Byrne, Linda; Zuo, Sai; Xu, Yifeng

2016-07-30

Relying on the absence, presence of level of symptomatology may not provide an adequate indication of the effects of treatment for depression, nor sufficient information for the development of treatment plans that meet patients' needs. Using a prospective, multi-centered, and observational design, the present study surveyed a large sample of outpatients with depression in China (n=9855). The 17-item Hamilton Rating Scale for Depression (HRSD-17) and the Remission Evaluation and Mood Inventory Tool (REMIT) were administered at baseline, two weeks later and 4 weeks, to assess patients' self-reported symptoms and general sense of mental health and wellbeing. Of 9855 outpatients, 91.3% were diagnosed as experiencing moderate to severe depression. The patients reported significant improvement over time on both depressive symptoms and general sense after 4-week treatment. The effect sizes of change in general sense were lower than those in symptoms at both two week and four week follow-up. Treatment effects on both general sense and depressive symptomatology were associated with demographic and clinical factors. The findings indicate that a focus on both general sense of mental health and wellbeing in addition to depressive symptomatology will provide clinicians, researchers and patients themselves with a broader perspective of the status of patients. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

PubMed Central

Koleti, Amar; Terryn, Raymond; Stathias, Vasileios; Chung, Caty; Cooper, Daniel J; Turner, John P; Vidović, Dušica; Forlin, Michele; Kelley, Tanya T; D’Urso, Alessandro; Allen, Bryce K; Torre, Denis; Jagodnik, Kathleen M; Wang, Lily; Jenkins, Sherry L; Mader, Christopher; Niu, Wen; Fazel, Mehdi; Mahi, Naim; Pilarczyk, Marcin; Clark, Nicholas; Shamsaei, Behrouz; Meller, Jarek; Vasiliauskas, Juozas; Reichard, John; Medvedovic, Mario; Ma’ayan, Avi; Pillai, Ajay

2018-01-01

Abstract The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national consortium funded by the NIH to generate a diverse and extensive reference library of cell-based perturbation-response signatures, along with novel data analytics tools to improve our understanding of human diseases at the systems level. In contrast to other large-scale data generation efforts, LINCS Data and Signature Generation Centers (DSGCs) employ a wide range of assay technologies cataloging diverse cellular responses. Integration of, and unified access to LINCS data has therefore been particularly challenging. The Big Data to Knowledge (BD2K) LINCS Data Coordination and Integration Center (DCIC) has developed data standards specifications, data processing pipelines, and a suite of end-user software tools to integrate and annotate LINCS-generated data, to make LINCS signatures searchable and usable for different types of users. Here, we describe the LINCS Data Portal (LDP) (http://lincsportal.ccs.miami.edu/), a unified web interface to access datasets generated by the LINCS DSGCs, and its underlying database, LINCS Data Registry (LDR). LINCS data served on the LDP contains extensive metadata and curated annotations. We highlight the features of the LDP user interface that is designed to enable search, browsing, exploration, download and analysis of LINCS data and related curated content. PMID:29140462

Regional and local land subsidence at the Venice coastland by TerraSAR-X PSI

NASA Astrophysics Data System (ADS)

Tosi, L.; Strozzi, T.; Da Lio, C.; Teatini, P.

2015-11-01

Land subsidence occurred at the Venice coastland over the 2008-2011 period has been investigated by Persistent Scatterer Interferometry (PSI) using a stack of 90 TerraSAR-X stripmap images with a 3 m resolution and a 11-day revisiting time. The regular X-band SAR acquisitions over more than three years coupled with the very-high image resolution has significantly improved the monitoring of ground displacements at regional and local scales, e.g., the entire lagoon, especially the historical palaces, the MoSE large structures under construction at the lagoon inlets to disconnect the lagoon from the Adriatic Sea during high tides, and single small structures scattered within the lagoon environments. Our results show that subsidence is characterized by a certain variability at the regional scale with superimposed important local displacements. The movements range from a gentle uplift to subsidence rates of up to 35 mm yr-1. For instance, settlements of 30-35 mm yr-1 have been detected at the three lagoon inlets in correspondence of the MoSE works, and local sinking bowls up to 10 mm yr-1 connected with the construction of new large buildings or restoration works have been measured in the Venice and Chioggia historical centers. Focusing on the city of Venice, the mean subsidence of 1.1 ± 1.0 mm yr-1 confirms the general stability of the historical center.

Near Earth Asteroid Scout Thrust and Torque Model

NASA Technical Reports Server (NTRS)

Heaton, Andrew; Ahmad, Naeem; Miller, Kyle

2017-01-01

The Near Earth Asteroid (NEA) Scout is a solar sail mission whose objective is to scout at least one Near Earth Asteroid in preparation for manned missions to asteroids. NEA Scout will use a solar sail as the primary means of propulsion. Thus it is important for mission planning to accurately characterize the thrust of the sail. Additionally, the solar sail creates a relatively large solar disturbance torque that must be mitigated. For early mission design studies a flat plate model of the solar sail with a fixed center of pressure was adequate, but as mission concepts and the sail design matured, greater fidelity was required. Here we discuss the progress to a three-dimensional sail model that includes the effects of tension and thermal deformation that has been derived from a large structural Finite Element Model (FEM) developed by the Langley Research Center. We have found that the deformed sail membrane affects torque relatively much more than thrust. We have also found that other than uncertainty over the precise shape, the effect of small (approximately millimeter scale) wrinkles on the diffusivity of the sail is the leading remaining source of uncertainty. We demonstrate that millimeter-scale wrinkles can be modeled analytically as a change in the fraction of specular reflection. Finally we discuss the implications of these results for the NEA Scout mission.

Conduct of Occupational Health During Major Disasters: A Comparison of Literature on Occupational Health Issues in the World Trade Center Terrorist Attack and the Fukushima Nuclear Power Plant Accident.

PubMed

Toyoda, Hiroyuki; Mori, Koji

2017-01-01

Workers who respond to large-scale disasters can be exposed to health hazards that do not exist in routine work. It is assumed that learning from past cases is effective for preparing for and responding to such problems, but published information is still insufficient. Accordingly, we conducted a literature review about the health issues and occupational health activities at the World Trade Center (WTC) terrorist attack and at the Fukushima Nuclear Power Plant accident to investigate how occupational health activities during disasters should be conducted. Seven studies about the WTC attack were extracted and categorized into the following topics: "in relation to emergency systems including occupational health management"; "in relation to improvement and prevention of health effects and occupational hygiene"; and "in relation to care systems aimed at mitigating health effects." Studies about the Fukushima Nuclear Power Plant accident have been used in a previous review. We conclude that, to prevent health effects in workers who respond to large-scale disasters, it is necessary to incorporate occupational health regulations into the national response plan, and to develop practical support functions that enable support to continue for an extended period, training systems for workers with opportunities to report accidents, and care systems to mitigate the health effects.

Electronic medical record integration with a database for adult congenital heart disease: Early experience and progress in automating multicenter data collection.

PubMed

Broberg, Craig S; Mitchell, Julie; Rehel, Silven; Grant, Andrew; Gianola, Ann; Beninato, Peter; Winter, Christiane; Verstappen, Amy; Valente, Anne Marie; Weiss, Joseph; Zaidi, Ali; Earing, Michael G; Cook, Stephen; Daniels, Curt; Webb, Gary; Khairy, Paul; Marelli, Ariane; Gurvitz, Michelle Z; Sahn, David J

2015-10-01

The adoption of electronic health records (EHR) has created an opportunity for multicenter data collection, yet the feasibility and reliability of this methodology is unknown. The aim of this study was to integrate EHR data into a homogeneous central repository specifically addressing the field of adult congenital heart disease (ACHD). Target data variables were proposed and prioritized by consensus of investigators at five target ACHD programs. Database analysts determined which variables were available within their institutions' EHR and stratified their accessibility, and results were compared between centers. Data for patients seen in a single calendar year were extracted to a uniform database and subsequently consolidated. From 415 proposed target variables, only 28 were available in discrete formats at all centers. For variables of highest priority, 16/28 (57%) were available at all four sites, but only 11% for those of high priority. Integration was neither simple nor straightforward. Coding schemes in use for congenital heart diagnoses varied and would require additional user input for accurate mapping. There was considerable variability in procedure reporting formats and medication schemes, often with center-specific modifications. Despite the challenges, the final acquisition included limited data on 2161 patients, and allowed for population analysis of race/ethnicity, defect complexity, and body morphometrics. Large-scale multicenter automated data acquisition from EHRs is feasible yet challenging. Obstacles stem from variability in data formats, coding schemes, and adoption of non-standard lists within each EHR. The success of large-scale multicenter ACHD research will require institution-specific data integration efforts. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Role of Intracranial Pressure Monitoring in Management of Patients with Severe Traumatic Brain Injury: Results of a Large Level I Trauma Center in Southern Iran.

PubMed

Khalili, Hosseinali; Sadraei, Nazanin; Niakan, Amin; Ghaffarpasand, Fariborz; Sadraei, Amin

2016-10-01

To determine the role of intracranial pressure (ICP) monitoring in management of patients with severe traumatic brain injury (TBI) admitted to a large level I trauma center in Southern Iran. This was a cohort study performed during a 2-year period in a level I trauma center in Southern Iran including all adult patients (>16 years) with severe TBI (Glasgow Coma Scale [GCS] score, 3-8) who underwent ICP monitoring through ventriculostomy. The management was based on the recorded ICP values with threshold of 20 mm Hg. Decompressive craniectomy was performed in patients with intractable intracranial hypertension (persistent ICP ≥25 mm Hg). In unresponsive patients, barbiturate coma was induced. Patients were followed for 6 months and Glasgow Outcome Scale Extended was recorded. The determinants of favorable and unfavorable outcome were also determined. Overall, we included 248 patients with mean age of 34.6 ± 16.6 years, among whom there were 216 men (87.1%) and 32 women (12.9%). Eighty-five patients (34.2%) had favorable and 163 (65.8%) unfavorable outcomes. Those with favorable outcome had significantly lower age (P = 0.004), higher GCS score on admission (P < 0.001), lower Rotterdam score (P = 0.035), fewer episodes of intracranial hypertension (P < 0.001), and lower maximum recorded ICP (P = 0.041). These factors remained statistically significant after elimination of confounders by multivariate logistic regression model. Age, GCS score on admission, Rotterdam score, intracranial hypertension, and maximum recorded ICP are important determinants of outcome in patients with severe TBI. ICP monitoring assisted us in targeted therapy and management of patients with severe TBI. Copyright © 2016 Elsevier Inc. All rights reserved.

Psychometric validity of the Cochlear Implant Function Index (CIFI): a quality of life assessment tool for adult cochlear implant users.

PubMed

Coelho, Daniel H; Hammerschlag, Paul E; Bat-Chava, Yael; Kohan, Darius

2009-06-01

The Cochlear Implant Function Index (CIFI) is created to assess adult cochlear implant (CI) auditory effectiveness in real world situations. Our objective is to evaluate the CIFI as a reliable psychometric tool to assess 1) reliance on visual assistance, 2) telephone use, 3) communication at work, 4) 'hearing' in noise, 5) in groups, and 6) in large room settings. Based upon Guttman scaling properties, the CIFI elicits implanted respondent's functional level with auditory independence from Level 1 (still requiring signing) to level 4 (without any help beyond CI). A blinded, retrospective questionnaire is anonymously answered by cochlear implant recipients. CI centers of tertiary care medical centers, CI support group, and an interactive web page of a hearing and speech center in a large metropolitan region. 245 respondents from a varied adult CI population implanted for one month to 19 years prior to answering the questionnaire. An assessment tool of CI function. A coefficient of reproducibility (CR) for the Guttman scale format equal or greater than 0.90, indicating good scalability. CR in the CIFI was above 0.90. Effective scalability and mean scores from 2.5 to 3.5 for the six areas examined (1.00-4.00) were achieved. The psychometric properties of this user friendly survey demonstrate consistently good scalability. Based on these findings, the CIFI provides a validated tool that can be used for systematic comparisons between groups of patients or for follow-up outcomes in patients who use cochlear implants. Further study is indicated to correlate CIFI scores with sound and speech perception scores. Copyright 2009 John Wiley & Sons, Ltd.

Sensitivity of Age-of-Air Calculations to the Choice of Advection Scheme

NASA Technical Reports Server (NTRS)

Eluszkiewicz, Janusz; Hemler, Richard S.; Mahlman, Jerry D.; Bruhwiler, Lori; Takacs, Lawrence L.

2000-01-01

The age of air has recently emerged as a diagnostic of atmospheric transport unaffected by chemical parameterizations, and the features in the age distributions computed in models have been interpreted in terms of the models' large-scale circulation field. This study shows, however, that in addition to the simulated large-scale circulation, three-dimensional age calculations can also be affected by the choice of advection scheme employed in solving the tracer continuity equation, Specifically, using the 3.0deg latitude X 3.6deg longitude and 40 vertical level version of the Geophysical Fluid Dynamics Laboratory SKYHI GCM and six online transport schemes ranging from Eulerian through semi-Lagrangian to fully Lagrangian, it will be demonstrated that the oldest ages are obtained using the nondiffusive centered-difference schemes while the youngest ages are computed with a semi-Lagrangian transport (SLT) scheme. The centered- difference schemes are capable of producing ages older than 10 years in the mesosphere, thus eliminating the "young bias" found in previous age-of-air calculations. At this stage, only limited intuitive explanations can be advanced for this sensitivity of age-of-air calculations to the choice of advection scheme, In particular, age distributions computed online with the National Center for Atmospheric Research Community Climate Model (MACCM3) using different varieties of the SLT scheme are substantially older than the SKYHI SLT distribution. The different varieties, including a noninterpolating-in-the-vertical version (which is essentially centered-difference in the vertical), also produce a narrower range of age distributions than the suite of advection schemes employed in the SKYHI model. While additional MACCM3 experiments with a wider range of schemes would be necessary to provide more definitive insights, the older and less variable MACCM3 age distributions can plausibly be interpreted as being due to the semi-implicit semi-Lagrangian dynamics employed in the MACCM3. This type of dynamical core (employed with a 60-min time step) is likely to reduce SLT's interpolation errors that are compounded by the short-term variability characteristic of the explicit centered-difference dynamics employed in the SKYHI model (time step of 3 min). In the extreme case of a very slowly varying circulation, the choice of advection scheme has no effect on two-dimensional (latitude-height) age-of-air calculations, owing to the smooth nature of the transport circulation in 2D models. These results suggest that nondiffusive schemes may be the preferred choice for multiyear simulations of tracers not overly sensitive to the requirement of monotonicity (this category includes many greenhouse gases). At the same time, age-of-air calculations offer a simple quantitative diagnostic of a scheme's long-term diffusive properties and may help in the evaluation of dynamical cores in multiyear integrations. On the other hand, the sensitivity of the computed ages to the model numerics calls for caution in using age of air as a diagnostic of a GCM's large-scale circulation field.

THE EFFECT OF INTERMITTENT GYRO-SCALE SLAB TURBULENCE ON PARALLEL AND PERPENDICULAR COSMIC-RAY TRANSPORT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Le Roux, J. A.

Earlier work based on nonlinear guiding center (NLGC) theory suggested that perpendicular cosmic-ray transport is diffusive when cosmic rays encounter random three-dimensional magnetohydrodynamic turbulence dominated by uniform two-dimensional (2D) turbulence with a minor uniform slab turbulence component. In this approach large-scale perpendicular cosmic-ray transport is due to cosmic rays microscopically diffusing along the meandering magnetic field dominated by 2D turbulence because of gyroresonant interactions with slab turbulence. However, turbulence in the solar wind is intermittent and it has been suggested that intermittent turbulence might be responsible for the observation of 'dropout' events in solar energetic particle fluxes on small scales.more » In a previous paper le Roux et al. suggested, using NLGC theory as a basis, that if gyro-scale slab turbulence is intermittent, large-scale perpendicular cosmic-ray transport in weak uniform 2D turbulence will be superdiffusive or subdiffusive depending on the statistical characteristics of the intermittent slab turbulence. In this paper we expand and refine our previous work further by investigating how both parallel and perpendicular transport are affected by intermittent slab turbulence for weak as well as strong uniform 2D turbulence. The main new finding is that both parallel and perpendicular transport are the net effect of an interplay between diffusive and nondiffusive (superdiffusive or subdiffusive) transport effects as a consequence of this intermittency.« less

Large scale features and energetics of the hybrid subtropical low `Duck' over the Tasman Sea

NASA Astrophysics Data System (ADS)

Pezza, Alexandre Bernardes; Garde, Luke Andrew; Veiga, José Augusto Paixão; Simmonds, Ian

2014-01-01

New aspects of the genesis and partial tropical transition of a rare hybrid subtropical cyclone on the eastern Australian coast are presented. The `Duck' (March 2001) attracted more recent attention due to its underlying genesis mechanisms being remarkably similar to the first South Atlantic hurricane (March 2004). Here we put this cyclone in climate perspective, showing that it belongs to a class within the 1 % lowest frequency percentile in the Southern Hemisphere as a function of its thermal evolution. A large scale analysis reveals a combined influence from an existing tropical cyclone and a persistent mid-latitude block. A Lagrangian tracer showed that the upper level air parcels arriving at the cyclone's center had been modified by the blocking. Lorenz energetics is used to identify connections with both tropical and extratropical processes, and reveal how these create the large scale environment conducive to the development of the vortex. The results reveal that the blocking exerted the most important influence, with a strong peak in barotropic generation of kinetic energy over a large area traversed by the air parcels just before genesis. A secondary peak also coincided with the first time the cyclone developed an upper level warm core, but with insufficient amplitude to allow for a full tropical transition. The applications of this technique are numerous and promising, particularly on the use of global climate models to infer changes in environmental parameters associated with severe storms.

Projections of the Ganges-Brahmaputra precipitation: downscaled from GCM predictors

USGS Publications Warehouse

Pervez, Md Shahriar; Henebry, Geoffrey M.

2014-01-01

Downscaling Global Climate Model (GCM) projections of future climate is critical for impact studies. Downscaling enables use of GCM experiments for regional scale impact studies by generating regionally specific forecasts connecting global scale predictions and regional scale dynamics. We employed the Statistical Downscaling Model (SDSM) to downscale 21st century precipitation for two data-sparse hydrologically challenging river basins in South Asia—the Ganges and the Brahmaputra. We used CGCM3.1 by Canadian Center for Climate Modeling and Analysis version 3.1 predictors in downscaling the precipitation. Downscaling was performed on the basis of established relationships between historical Global Summary of Day observed precipitation records from 43 stations and National Center for Environmental Prediction re-analysis large scale atmospheric predictors. Although the selection of predictors was challenging during the set-up of SDSM, they were found to be indicative of important physical forcings in the basins. The precipitation of both basins was largely influenced by geopotential height: the Ganges precipitation was modulated by the U component of the wind and specific humidity at 500 and 1000 h Pa pressure levels; whereas, the Brahmaputra precipitation was modulated by the V component of the wind at 850 and 1000 h Pa pressure levels. The evaluation of the SDSM performance indicated that model accuracy for reproducing precipitation at the monthly scale was acceptable, but at the daily scale the model inadequately simulated some daily extreme precipitation events. Therefore, while the downscaled precipitation may not be the suitable input to analyze future extreme flooding or drought events, it could be adequate for analysis of future freshwater availability. Analysis of the CGCM3.1 downscaled precipitation projection with respect to observed precipitation reveals that the precipitation regime in each basin may be significantly impacted by climate change. Precipitation during and after the monsoon is likely to increase in both basins under the A1B and A2 emission scenarios; whereas, the pre-monsoon precipitation is likely to decrease. Peak monsoon precipitation is likely to shift from July to August, and may impact the livelihoods of large rural populations linked to subsistence agriculture in the basins. Uncertainty analysis of the downscaled precipitation indicated that the uncertainty in the downscaled precipitation was less than the uncertainty in the original CGCM3.1 precipitation; hence, the CGCM3.1 downscaled precipitation was a better input for the regional hydrological impact studies. However, downscaled precipitation from multiple GCMs is suggested for comprehensive impact studies.

Step scaling and the Yang-Mills gradient flow

NASA Astrophysics Data System (ADS)

Lüscher, Martin

2014-06-01

The use of the Yang-Mills gradient flow in step-scaling studies of lattice QCD is expected to lead to results of unprecedented precision. Step scaling is usually based on the Schrödinger functional, where time ranges over an interval [0 , T] and all fields satisfy Dirichlet boundary conditions at time 0 and T. In these calculations, potentially important sources of systematic errors are boundary lattice effects and the infamous topology-freezing problem. The latter is here shown to be absent if Neumann instead of Dirichlet boundary conditions are imposed on the gauge field at time 0. Moreover, the expectation values of gauge-invariant local fields at positive flow time (and of other well localized observables) that reside in the center of the space-time volume are found to be largely insensitive to the boundary lattice effects.

Molecular Origins of Mesoscale Ordering in a Metalloamphiphile Phase

PubMed Central

2015-01-01

Controlling the assembly of soft and deformable molecular aggregates into mesoscale structures is essential for understanding and developing a broad range of processes including rare earth extraction and cleaning of water, as well as for developing materials with unique properties. By combined synchrotron small- and wide-angle X-ray scattering with large-scale atomistic molecular dynamics simulations we analyze here a metalloamphiphile–oil solution that organizes on multiple length scales. The molecules associate into aggregates, and aggregates flocculate into meso-ordered phases. Our study demonstrates that dipolar interactions, centered on the amphiphile headgroup, bridge ionic aggregate cores and drive aggregate flocculation. By identifying specific intermolecular interactions that drive mesoscale ordering in solution, we bridge two different length scales that are classically addressed separately. Our results highlight the importance of individual intermolecular interactions in driving mesoscale ordering. PMID:27163014

The 2-MEV model: Constancy of adolescent environmental values within an 8-year time frame

NASA Astrophysics Data System (ADS)

Bogner, F. X.; Johnson, B.; Buxner, S.; Felix, L.

2015-08-01

The 2-MEV model is a widely used tool to monitor children's environmental perception by scoring individual values. Although the scale's validity has been confirmed repeatedly and independently as well as the scale is in usage within more than two dozen language units all over the world, longitudinal properties still need clarification. The purpose of the present study therefore was to validate the 2-MEV scale based on a large data basis of 10,676 children collected over an eight-year period. Cohorts of three different US states contributed to the sample by responding to a paper-and-pencil questionnaire within their pre-test initiatives in the context of field center programs. Since we used only the pre-program 2-MEV scale results (which is before participation in education programs), the data were clearly unspoiled by any follow-up interventions. The purpose of analysis was fourfold: First, to test and confirm the hypothesized factorized structure for the large data set and for the subsample of each of the three states. Second, to analyze the scoring pattern across the eight years' time range for both preservation and utilitarian preferences. Third, to investigate any age effects in the extracted factors. Finally, to extract suitable recommendations for educational implementation efforts.

How do glacier inventory data aid global glacier assessments and projections?

NASA Astrophysics Data System (ADS)

Hock, R.

2017-12-01

Large-scale glacier modeling relies heavily on datasets that are collected by many individuals across the globe, but managed and maintained in a coordinated fashion by international data centers. The Global Terrestrial Network for Glaciers (GTN-G) provides the framework for coordinating and making available a suite of data sets such as the Randolph Glacier Inventory (RGI), the Glacier Thickness Dataset or the World Glacier Inventory (WGI). These datasets have greatly increased our ability to assess global-scale glacier mass changes. These data have also been vital for projecting the glacier mass changes of all mountain glaciers in the world outside the Greenland and Antarctic ice sheet, a total >200,000 glaciers covering an area of more than 700,000 km2. Using forcing from 8 to 15 GCMs and 4 different emission scenarios, global-scale glacier evolution models project multi-model mean net mass losses of all glaciers between 7 cm and 24 cm sea-level equivalent by the end of the 21st century. Projected mass losses vary greatly depending on the choice of the forcing climate and emission scenario. Insufficiently constrained model parameters likely are an important reason for large differences found among these studies even when forced by the same emission scenario, especially on regional scales.

Large-scale modeling of the primary visual cortex: influence of cortical architecture upon neuronal response.

PubMed

McLaughlin, David; Shapley, Robert; Shelley, Michael

2003-01-01

A large-scale computational model of a local patch of input layer 4 [Formula: see text] of the primary visual cortex (V1) of the macaque monkey, together with a coarse-grained reduction of the model, are used to understand potential effects of cortical architecture upon neuronal performance. Both the large-scale point neuron model and its asymptotic reduction are described. The work focuses upon orientation preference and selectivity, and upon the spatial distribution of neuronal responses across the cortical layer. Emphasis is given to the role of cortical architecture (the geometry of synaptic connectivity, of the ordered and disordered structure of input feature maps, and of their interplay) as mechanisms underlying cortical responses within the model. Specifically: (i) Distinct characteristics of model neuronal responses (firing rates and orientation selectivity) as they depend upon the neuron's location within the cortical layer relative to the pinwheel centers of the map of orientation preference; (ii) A time independent (DC) elevation in cortico-cortical conductances within the model, in contrast to a "push-pull" antagonism between excitation and inhibition; (iii) The use of asymptotic analysis to unveil mechanisms which underly these performances of the model; (iv) A discussion of emerging experimental data. The work illustrates that large-scale scientific computation--coupled together with analytical reduction, mathematical analysis, and experimental data, can provide significant understanding and intuition about the possible mechanisms of cortical response. It also illustrates that the idealization which is a necessary part of theoretical modeling can outline in sharp relief the consequences of differing alternative interpretations and mechanisms--with final arbiter being a body of experimental evidence whose measurements address the consequences of these analyses.

Large-scale brain network coupling predicts acute nicotine abstinence effects on craving and cognitive function.

PubMed

Lerman, Caryn; Gu, Hong; Loughead, James; Ruparel, Kosha; Yang, Yihong; Stein, Elliot A

2014-05-01

Interactions of large-scale brain networks may underlie cognitive dysfunctions in psychiatric and addictive disorders. To test the hypothesis that the strength of coupling among 3 large-scale brain networks--salience, executive control, and default mode--will reflect the state of nicotine withdrawal (vs smoking satiety) and will predict abstinence-induced craving and cognitive deficits and to develop a resource allocation index (RAI) that reflects the combined strength of interactions among the 3 large-scale networks. A within-subject functional magnetic resonance imaging study in an academic medical center compared resting-state functional connectivity coherence strength after 24 hours of abstinence and after smoking satiety. We examined the relationship of abstinence-induced changes in the RAI with alterations in subjective, behavioral, and neural functions. We included 37 healthy smoking volunteers, aged 19 to 61 years, for analyses. Twenty-four hours of abstinence vs smoking satiety. Inter-network connectivity strength (primary) and the relationship with subjective, behavioral, and neural measures of nicotine withdrawal during abstinence vs smoking satiety states (secondary). The RAI was significantly lower in the abstinent compared with the smoking satiety states (left RAI, P = .002; right RAI, P = .04), suggesting weaker inhibition between the default mode and salience networks. Weaker inter-network connectivity (reduced RAI) predicted abstinence-induced cravings to smoke (r = -0.59; P = .007) and less suppression of default mode activity during performance of a subsequent working memory task (ventromedial prefrontal cortex, r = -0.66, P = .003; posterior cingulate cortex, r = -0.65, P = .001). Alterations in coupling of the salience and default mode networks and the inability to disengage from the default mode network may be critical in cognitive/affective alterations that underlie nicotine dependence.

Restoration of the Hypersonic Tunnel Facility at NASA Glenn Research Center, Plum Brook Station

NASA Technical Reports Server (NTRS)

Woodling, Mark A.

2000-01-01

The NASA Glenn Research Center's Hypersonic Tunnel Facility (HTF), located at the Plum Brook Station in Sandusky, Ohio, is a non-vitiated, free-jet facility, capable of testing large-scale propulsion systems at Mach Numbers from 5 to 7. As a result of a component failure in September of 1996, a restoration project was initiated in mid- 1997 to repair the damage to the facility. Following the 2-1/2 year effort, the HTF has been returned to an operational condition. Significant repairs and operational improvements have been implemented in order to ensure facility reliability and personnel safety. As of January 2000, this unique, state-of-the-art facility was ready for integrated systems testing.

Strategy, structure, and patient quality outcomes in ambulatory surgery centers (1997-2004).

PubMed

Chukmaitov, Askar; Devers, Kelly J; Harless, David W; Menachemi, Nir; Brooks, Robert G

2011-04-01

The purpose of this study was to examine potential associations among ambulatory surgery centers' (ASCs) organizational strategy, structure, and quality performance. The authors obtained several large-scale, all-payer claims data sets for the 1997 to 2004 period. The authors operationalized quality performance as unplanned hospitalizations at 30 days after outpatient arthroscopy and colonoscopy procedures. The authors draw on related organizational theory, behavior, and health services research literatures to develop their conceptual framework and hypotheses and fitted fixed and random effects Poisson regression models with the count of unplanned hospitalizations. Consistent with the key hypotheses formulated, the findings suggest that higher levels of specialization and the volume of procedures may be associated with a decrease in unplanned hospitalizations at ASCs.

Large-Scale Cryogenic Testing of Launch Vehicle Ground Systems at the Kennedy Space Center

NASA Technical Reports Server (NTRS)

Ernst, E. W.; Sass, J. P.; Lobemeyer, D. A.; Sojourner, S. J.; Hatfield, W. H.; Rewinkel, D. A.

2007-01-01

The development of a new launch vehicle to support NASA's future exploration plans requires significant redesign and upgrade of Kennedy Space Center's (KSC) launch pad and ground support equipment systems. In many cases, specialized test equipment and systems will be required to certify the function of the new system designs under simulated operational conditions, including propellant loading. This paper provides an overview of the cryogenic test infrastructure that is in place at KSC to conduct development and qualification testing that ranges from the component level to the integrated-system level. An overview of the major cryogenic test facilities will be provided, along with a detailed explanation of the technology focus area for each facility

NASA Marshall Space Flight Center Controls Systems Design and Analysis Branch

NASA Technical Reports Server (NTRS)

Gilligan, Eric

2014-01-01

Marshall Space Flight Center maintains a critical national capability in the analysis of launch vehicle flight dynamics and flight certification of GN&C algorithms. MSFC analysts are domain experts in the areas of flexible-body dynamics and control-structure interaction, thrust vector control, sloshing propellant dynamics, and advanced statistical methods. Marshall's modeling and simulation expertise has supported manned spaceflight for over 50 years. Marshall's unparalleled capability in launch vehicle guidance, navigation, and control technology stems from its rich heritage in developing, integrating, and testing launch vehicle GN&C systems dating to the early Mercury-Redstone and Saturn vehicles. The Marshall team is continuously developing novel methods for design, including advanced techniques for large-scale optimization and analysis.

Tight-binding calculation studies of vacancy and adatom defects in graphene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Wei; Lu, Wen-Cai; Zhang, Hong-Xing

2016-02-19

Computational studies of complex defects in graphene usually need to deal with a larger number of atoms than the current first-principles methods can handle. We show a recently developed three-center tight-binding potential for carbon is very efficient for large scale atomistic simulations and can accurately describe the structures and energies of various defects in graphene. Using the three-center tight-binding potential, we have systematically studied the stable structures and formation energies of vacancy and embedded-atom defects of various sizes up to 4 vacancies and 4 embedded atoms in graphene. In conclusion, our calculations reveal low-energy defect structures and provide a moremore » comprehensive understanding of the structures and stability of defects in graphene.« less

KSC-08pd2189

NASA Image and Video Library

2008-07-29

CAPE CANAVERAL, Fla. – At NASA's Kennedy Space Center, workers from NASA's Goddard Space Flight Center roll the Cosmic Origins Spectrograph, or COS, into the clean room of the Payload Hazardous Servicing Facility. The COS will be installed on the Hubble Space Telescope on space shuttle Atlantis' STS-125 mission. COS will be the most sensitive ultraviolet spectrograph ever flown on Hubble and will probe the "cosmic web" - the large-scale structure of the universe whose form is determined by the gravity of dark matter and is traced by galaxies and intergalactic gas. COS's far-ultraviolet channel has a sensitivity 30 times greater than that of previous spectroscopic instruments for the detection of extremely low light levels. Launch of STS-125 is targeted for Oct. 8. Photo credit: NASA/Jack Pfaller

Finding topological center of a geographic space via road network

NASA Astrophysics Data System (ADS)

Gao, Liang; Miao, Yanan; Qin, Yuhao; Zhao, Xiaomei; Gao, Zi-You

2015-02-01

Previous studies show that the center of a geographic space is of great importance in urban and regional studies, including study of population distribution, urban growth modeling, and scaling properties of urban systems, etc. But how to well define and how to efficiently extract the center of a geographic space are still largely unknown. Recently, Jiang et al. have presented a definition of topological center by their block detection (BD) algorithm. Despite the fact that they first introduced the definition and discovered the 'true center', in human minds, their algorithm left several redundancies in its traversal process. Here, we propose an alternative road-cycle detection (RCD) algorithm to find the topological center, which extracts the outmost road-cycle recursively. To foster the application of the topological center in related research fields, we first reproduce the BD algorithm in Python (pyBD), then implement the RCD algorithm in two ways: the ArcPy implementation (arcRCD) and the Python implementation (pyRCD). After the experiments on twenty-four typical road networks, we find that the results of our RCD algorithm are consistent with those of Jiang's BD algorithm. We also find that the RCD algorithm is at least seven times more efficient than the BD algorithm on all the ten typical road networks.

Validation of the DRAGON score in 12 stroke centers in anterior and posterior circulation.

PubMed

Strbian, Daniel; Seiffge, David J; Breuer, Lorenz; Numminen, Heikki; Michel, Patrik; Meretoja, Atte; Coote, Skye; Bordet, Régis; Obach, Victor; Weder, Bruno; Jung, Simon; Caso, Valeria; Curtze, Sami; Ollikainen, Jyrki; Lyrer, Philippe A; Eskandari, Ashraf; Mattle, Heinrich P; Chamorro, Angel; Leys, Didier; Bladin, Christopher; Davis, Stephen M; Köhrmann, Martin; Engelter, Stefan T; Tatlisumak, Turgut

2013-10-01

The DRAGON score predicts functional outcome in the hyperacute phase of intravenous thrombolysis treatment of ischemic stroke patients. We aimed to validate the score in a large multicenter cohort in anterior and posterior circulation. Prospectively collected data of consecutive ischemic stroke patients who received intravenous thrombolysis in 12 stroke centers were merged (n=5471). We excluded patients lacking data necessary to calculate the score and patients with missing 3-month modified Rankin scale scores. The final cohort comprised 4519 eligible patients. We assessed the performance of the DRAGON score with area under the receiver operating characteristic curve in the whole cohort for both good (modified Rankin scale score, 0-2) and miserable (modified Rankin scale score, 5-6) outcomes. Area under the receiver operating characteristic curve was 0.84 (0.82-0.85) for miserable outcome and 0.82 (0.80-0.83) for good outcome. Proportions of patients with good outcome were 96%, 93%, 78%, and 0% for 0 to 1, 2, 3, and 8 to 10 score points, respectively. Proportions of patients with miserable outcome were 0%, 2%, 4%, 89%, and 97% for 0 to 1, 2, 3, 8, and 9 to 10 points, respectively. When tested separately for anterior and posterior circulation, there was no difference in performance (P=0.55); areas under the receiver operating characteristic curve were 0.84 (0.83-0.86) and 0.82 (0.78-0.87), respectively. No sex-related difference in performance was observed (P=0.25). The DRAGON score showed very good performance in the large merged cohort in both anterior and posterior circulation strokes. The DRAGON score provides rapid estimation of patient prognosis and supports clinical decision-making in the hyperacute phase of stroke care (eg, when invasive add-on strategies are considered).

Amp: A modular approach to machine learning in atomistic simulations

NASA Astrophysics Data System (ADS)

Khorshidi, Alireza; Peterson, Andrew A.

2016-10-01

Electronic structure calculations, such as those employing Kohn-Sham density functional theory or ab initio wavefunction theories, have allowed for atomistic-level understandings of a wide variety of phenomena and properties of matter at small scales. However, the computational cost of electronic structure methods drastically increases with length and time scales, which makes these methods difficult for long time-scale molecular dynamics simulations or large-sized systems. Machine-learning techniques can provide accurate potentials that can match the quality of electronic structure calculations, provided sufficient training data. These potentials can then be used to rapidly simulate large and long time-scale phenomena at similar quality to the parent electronic structure approach. Machine-learning potentials usually take a bias-free mathematical form and can be readily developed for a wide variety of systems. Electronic structure calculations have favorable properties-namely that they are noiseless and targeted training data can be produced on-demand-that make them particularly well-suited for machine learning. This paper discusses our modular approach to atomistic machine learning through the development of the open-source Atomistic Machine-learning Package (Amp), which allows for representations of both the total and atom-centered potential energy surface, in both periodic and non-periodic systems. Potentials developed through the atom-centered approach are simultaneously applicable for systems with various sizes. Interpolation can be enhanced by introducing custom descriptors of the local environment. We demonstrate this in the current work for Gaussian-type, bispectrum, and Zernike-type descriptors. Amp has an intuitive and modular structure with an interface through the python scripting language yet has parallelizable fortran components for demanding tasks; it is designed to integrate closely with the widely used Atomic Simulation Environment (ASE), which makes it compatible with a wide variety of commercial and open-source electronic structure codes. We finally demonstrate that the neural network model inside Amp can accurately interpolate electronic structure energies as well as forces of thousands of multi-species atomic systems.

How large a dataset should be in order to estimate scaling exponents and other statistics correctly in studies of solar wind turbulence

NASA Astrophysics Data System (ADS)

Rowlands, G.; Kiyani, K. H.; Chapman, S. C.; Watkins, N. W.

2009-12-01

Quantitative analysis of solar wind fluctuations are often performed in the context of intermittent turbulence and center around methods to quantify statistical scaling, such as power spectra and structure functions which assume a stationary process. The solar wind exhibits large scale secular changes and so the question arises as to whether the timeseries of the fluctuations is non-stationary. One approach is to seek a local stationarity by parsing the time interval over which statistical analysis is performed. Hence, natural systems such as the solar wind unavoidably provide observations over restricted intervals. Consequently, due to a reduction of sample size leading to poorer estimates, a stationary stochastic process (time series) can yield anomalous time variation in the scaling exponents, suggestive of nonstationarity. The variance in the estimates of scaling exponents computed from an interval of N observations is known for finite variance processes to vary as ~1/N as N becomes large for certain statistical estimators; however, the convergence to this behavior will depend on the details of the process, and may be slow. We study the variation in the scaling of second-order moments of the time-series increments with N for a variety of synthetic and “real world” time series, and we find that in particular for heavy tailed processes, for realizable N, one is far from this ~1/N limiting behavior. We propose a semiempirical estimate for the minimum N needed to make a meaningful estimate of the scaling exponents for model stochastic processes and compare these with some “real world” time series from the solar wind. With fewer datapoints the stationary timeseries becomes indistinguishable from a nonstationary process and we illustrate this with nonstationary synthetic datasets. Reference article: K. H. Kiyani, S. C. Chapman and N. W. Watkins, Phys. Rev. E 79, 036109 (2009).

Ecological scale and seasonal heterogeneity in the spatial behaviors of giant pandas.

PubMed

Zhang, Zejun; Sheppard, James K; Swaisgood, Ronald R; Wang, Guan; Nie, Yonggang; Wei, Wei; Zhao, Naxun; Wei, Fuwen

2014-01-01

We report on the first study to track the spatial behaviors of wild giant pandas (Ailuropoda melanoleuca) using high-resolution global positioning system (GPS) telemetry. Between 2008 and 2009, 4 pandas (2 male and 2 female) were tracked in Foping Reserve, China for an average of 305 days (± 54.8 SE). Panda home ranges were larger than those of previous very high frequency tracking studies, with a bimodal distribution of space-use and distinct winter and summer centers of activity. Home range sizes were larger in winter than in summer, although there was considerable individual variability. All tracked pandas exhibited individualistic, unoriented and multiphasic movement paths, with a high level of tortuosity within seasonal core habitats and directed, linear, large-scale movements between habitats. Pandas moved from low elevation winter habitats to high elevation (>2000 m) summer habitats in May, when temperatures averaged 17.5 °C (± 0.3 SE), and these large-scale movements took <1 month to complete. The peak in panda mean elevation occurred in Jul, after which they began slow, large-scale movements back to winter habitats that were completed in Nov. An adult female panda made 2 longdistance movements during the mating season. Pandas remain close to rivers and streams during winter, possibly reflecting the elevated water requirements to digest their high-fiber food. Panda movement path tortuosity and first-passage-time as a function of spatial scale indicated a mean peak in habitat search effort and patch use of approximately 700 m. Despite a high degree of spatial overlap between panda home ranges, particularly in winter, we detected neither avoidance nor attraction behavior between conspecifics. © 2012 Wiley Publishing Asia Pty Ltd, ISZS and IOZ/CAS.

Development of a refractive error quality of life scale for Thai adults (the REQ-Thai).

PubMed

Sukhawarn, Roongthip; Wiratchai, Nonglak; Tatsanavivat, Pyatat; Pitiyanuwat, Somwung; Kanato, Manop; Srivannaboon, Sabong; Guyatt, Gordon H

2011-08-01

To develop a scale for measuring refractive error quality of life (QOL) for Thai adults. The full survey comprised 424 respondents from 5 medical centers in Bangkok and from 3 medical centers in Chiangmai, Songkla and KhonKaen provinces. Participants were emmetropes and persons with refractive correction with visual acuity of 20/30 or better An item reduction process was employed by combining 3 methods-expert opinion, impact method and item-total correlation methods. The classical reliability testing and the validity testing including convergent, discriminative and construct validity was performed. The developed questionnaire comprised 87 items in 6 dimensions: 1) quality of vision, 2) visual function, 3) social function, 4) psychological function, 5) symptoms and 6) refractive correction problems. It is the 5-level Likert scale type. The Cronbach's Alpha coefficients of its dimensions ranged from 0.756 to 0. 979. All validity testing were shown to be valid. The construct validity was validated by the confirmatory factor analysis. A short version questionnaire comprised 48 items with good reliability and validity was also developed. This is the first validated instrument for measuring refractive error quality of life for Thai adults that was developed with strong research methodology and large sample size.

Large-scale natural gradient tracer test in sand and gravel, Cape Cod, Massachusetts: 2. Analysis of spatial moments for a nonreactive tracer

USGS Publications Warehouse

Garabedian, Stephen P.; LeBlanc, Dennis R.; Gelhar, Lynn W.; Celia, Michael A.

1991-01-01

A large-scale natural gradient tracer test was conducted to examine the transport of reactive and nonreactive tracers in a sand and gravel aquifer on Cape Cod, Massachusetts. As part of this test the transport of bromide, a nonreactive tracer, was monitored for about 280 m and quantified using spatial moments. The calculated mass of bromide for each sampling date varied between 85% and 105% of the injected mass using an estimated porosity of 0.39, and the center of mass moved at a nearly constant horizontal velocity of 0.42 m per day. A nonlinear change in the bromide longitudinal variance was observed during the first 26 m of travel distance, but afterward the variance followed a linear trend, indicating the longitudinal dispersivity had reached a constant value of 0.96 m. The transverse dispersivities were much smaller; transverse horizontal dispersivity was 1.8 cm, and transverse vertical dispersivity was about 1.5 mm.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shang Yazhuo; Hu Jun; Liu Honglai, E-mail: yazhuoshang@ecust.edu.c

Novel large-scale hollow ZnO spherical shells were synthesized by ionic liquids assisted hydrothermal oxidization of pure zinc powder without any catalyst at a relatively low temperature of 160 deg. C. X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM) patterns show that the shells are composed of ZnO and the structure of the shells is very unique. Textured flower-like ZnO consisting of ZnO rods is grown on the outer surfaces of shells forming a triple assembly. Room-temperature photoluminescence spectra of the oxidized material show a sharp peak at 379 nm and a wider broad peak centeredmore » at 498 nm. The possible growth mechanism of the triple assembly of ZnO is discussed in detail. - Graphical abstract: A proposed growth mechanism of large scale hollow ZnO. Bubbles provide the aggregation center for ionic liquids that leads to the formation of hollow Zn particle-dotted shells, buoyancy promotes shells to go upward, the breach occurs when shells are subjected to overpressure.« less

Software engineering risk factors in the implementation of a small electronic medical record system: the problem of scalability.

PubMed

Chiang, Michael F; Starren, Justin B

2002-01-01

The successful implementation of clinical information systems is difficult. In examining the reasons and potential solutions for this problem, the medical informatics community may benefit from the lessons of a rich body of software engineering and management literature about the failure of software projects. Based on previous studies, we present a conceptual framework for understanding the risk factors associated with large-scale projects. However, the vast majority of existing literature is based on large, enterprise-wide systems, and it unclear whether those results may be scaled down and applied to smaller projects such as departmental medical information systems. To examine this issue, we discuss the case study of a delayed electronic medical record implementation project in a small specialty practice at Columbia-Presbyterian Medical Center. While the factors contributing to the delay of this small project share some attributes with those found in larger organizations, there are important differences. The significance of these differences for groups implementing small medical information systems is discussed.

Dissociative recombination of the ground state of N2(+)

NASA Technical Reports Server (NTRS)

Guberman, Steven L.

1991-01-01

Large-scale calculations of the dissociative recombination cross sections and rates for the v = 0 level of the N2(+) ground state are reported, and the important role played by vibrationally excited Rydberg states lying both below and above the v = 0 level of the ion is demonstrated. The large-scale electronic wave function calculations were done using triple zeta plus polarization nuclear-centered-valence Gaussian basis sets. The electronic widths were obtained using smaller wave functions, and the cross sections were calculated on the basis of the multichannel quantum defect theory. The DR rate is calculated at 1.6 x 10 to the -7th x (Te/300) to the -0.37 cu cm/sec for Te in the range of 100 to 1000 K, and is found to be in excellent agreement with prior microwave afterglow experiments but in disagreement with recent merged beam results. It is inferred that the dominant mechanism for DR imparts sufficient energy to the product atoms to allow for escape from the Martian atmosphere.

Vibration and flutter characteristics of the SR7L large-scale propfan

NASA Technical Reports Server (NTRS)

August, Richard; Kaza, Krishna Rao V.

1988-01-01

An investigation of the vibration characteristics and aeroelastic stability of the SR7L Large-Scale Advanced Propfan was performed using a finite element blade model and an improved aeroelasticity code. Analyses were conducted for different blade pitch angles, blade support conditions, number of blades, rotational speeds, and freestream Mach numbers. A finite element model of the blade was used to determine the blade's vibration behavior and sensitivity to support stiffness. The calculated frequencies and mode shape obtained with this model agreed well with the published experimental data. A computer code recently developed at NASA Lewis Research Center and based on three-dimensional, unsteady, lifting surface aerodynamic theory was used for the aeroelastic analysis to examine the blade's stability at a cruise condition of Mach 0.8 at 1700 rpm. The results showed that the blade is stable for that operating point. However, a flutter condition was predicted if the cruise Mach number was increased to 0.9.

Direct EUV/X-Ray Modulation of the Ionosphere During the August 2017 Total Solar Eclipse

NASA Astrophysics Data System (ADS)

Mrak, Sebastijan; Semeter, Joshua; Drob, Douglas; Huba, J. D.

2018-05-01

The great American total solar eclipse of 21 August 2017 offered a fortuitous opportunity to study the response of the atmosphere and ionosphere using a myriad of ground instruments. We have used the network of U.S. Global Positioning System receivers to examine perturbations in maps of ionospheric total electron content (TEC). Coherent large-scale variations in TEC have been interpreted by others as gravity wave-induced traveling ionospheric disturbances. However, the solar disk had two active regions at that time, one near the center of the disk and one at the edge, which resulted in an irregular illumination pattern in the extreme ultraviolet (EUV)/X-ray bands. Using detailed EUV occultation maps calculated from the National Aeronautics and Space Administration Solar Dynamics Observatory Atmospheric Imaging Assembly images, we show excellent agreement between TEC perturbations and computed gradients in EUV illumination. The results strongly suggest that prominent large-scale TEC disturbances were consequences of direct EUV modulation, rather than gravity wave-induced traveling ionospheric disturbances.

Consciousness, cognition and brain networks: New perspectives.

PubMed

Aldana, E M; Valverde, J L; Fábregas, N

2016-10-01

A detailed analysis of the literature on consciousness and cognition mechanisms based on the neural networks theory is presented. The immune and inflammatory response to the anesthetic-surgical procedure induces modulation of neuronal plasticity by influencing higher cognitive functions. Anesthetic drugs can cause unconsciousness, producing a functional disruption of cortical and thalamic cortical integration complex. The external and internal perceptions are processed through an intricate network of neural connections, involving the higher nervous activity centers, especially the cerebral cortex. This requires an integrated model, formed by neural networks and their interactions with highly specialized regions, through large-scale networks, which are distributed throughout the brain collecting information flow of these perceptions. Functional and effective connectivity between large-scale networks, are essential for consciousness, unconsciousness and cognition. It is what is called the "human connectome" or map neural networks. Copyright © 2014 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

Kinetic description of large-scale low pressure glow discharges

NASA Astrophysics Data System (ADS)

Kortshagen, Uwe; Heil, Brian

1997-10-01

In recent years the so called ``nonlocal approximation'' to the solution of the electron Boltzmann equation has attracted considerable attention as an extremely efficient method for the kinetic modeling of low pressure discharges. However, it appears that modern discharges, which are optimized to provide large-scale plasma uniformity, are explicitly designed to work in a regime, in which the nonlocal approximation is no longer strictly valid. In the presentation we discuss results of a hybrid model, which is based on the natural division of the electron distribution function into a nonlocal body, which is determined by elastic collisions only, and a high energy part which requires a more complete treatment due to the action of inelastic collisions and wall losses of electrons. The method is applied to an inductively coupled low pressure discharge. We discuss the transition from plasma density profiles maximal on the discharge axis to plasma density profiles with off-center maxima, which has been observed in experiments. A positive feedback mechanism involved in this transition is pointed out.

The Large Scale Structure of the Galactic Magnetic Field and High Energy Cosmic Ray Anisotropy

NASA Astrophysics Data System (ADS)

Alvarez-Muñiz, Jaime; Stanev, Todor

2006-10-01

Measurements of the magnetic field in our Galaxy are complex and usually difficult to interpret. A spiral regular field in the disk is favored by observations, however the number of field reversals is still under debate. Measurements of the parity of the field across the Galactic plane are also very difficult due to the presence of the disk field itself. In this work we demonstrate that cosmic ray protons in the energy range 1018 to 1019eV, if accelerated near the center of the Galaxy, are sensitive to the large scale structure of the Galactic Magnetic Field (GMF). In particular if the field is of even parity, and the spiral field is bi-symmetric (BSS), ultra high energy protons will predominantly come from the Southern Galactic hemisphere, and predominantly from the Northern Galactic hemisphere if the field is of even parity and axi-symmetric (ASS). There is no sensitivity to the BSS or ASS configurations if the field is of odd parity.

Propagation of electromagnetic waves in a turbulent medium

NASA Technical Reports Server (NTRS)

Canuto, V. M.; Hartke, G. J.

1986-01-01

Theoretical modeling of the wealth of experimental data on propagation of electromagnetic radiation through turbulent media has centered on the use of the Heisenberg-Kolmogorov (HK) model, which is, however, valid only for medium to small sized eddies. Ad hoc modifications of the HK model to encompass the large-scale region of the eddy spectrum have been widely used, but a sound physical basis has been lacking. A model for large-scale turbulence that was recently proposed is applied to the above problem. The spectral density of the temperature field is derived and used to calculate the structure function of the index of refraction N. The result is compared with available data, yielding a reasonably good fit. The variance of N is also in accord with the data. The model is also applied to propagation effects. The phase structure function, covariance of the log amplitude, and variance of the log intensity are calculated. The calculated phase structure function is in excellent agreement with available data.

Linking Low-Frequency Large-Scale Circulation Patterns to Cold Air Outbreak Formation in the Northeastern North Atlantic

NASA Astrophysics Data System (ADS)

Papritz, L.; Grams, C. M.

2018-03-01

The regional variability of wintertime marine cold air outbreaks (CAOs) in the northeastern North Atlantic is studied focusing on the role of weather regimes in modulating the large-scale circulation. Each regime is characterized by a typical CAO frequency anomaly pattern and a corresponding imprint in air-sea heat fluxes. Cyclonically dominated regimes, Greenland blocking and the Atlantic ridge regime are found to provide favorable conditions for CAO formation in at least one major sea of the study region; CAO occurrence is suppressed, however, by blocked regimes whose associated anticyclones are centered over northern Europe (European / Scandinavian blocking). Kinematic trajectories reveal that strength and location of the storm tracks are closely linked to the pathways of CAO air masses and, thus, CAO occurrence. Finally, CAO frequencies are also linked to the strength of the stratospheric polar vortex, which is understood in terms of associated variations in the frequency of weather regimes.

Some further developments in the dynamic modelling and control of the large angle magnetic suspension test fixture

NASA Technical Reports Server (NTRS)

Britcher, Colin P.; Foster, Lucas E.

1994-01-01

A small-scale laboratory magnetic suspension system, the Large Angle Magnetic Suspension Test Fixture (LAMSTF) has been constructed at NASA Langley Research Center. This paper first presents some recent developments in the mathematical modelling of the system, particularly in the area of eddy current effects. It is shown that these effects are significant, but may be amenable to modelling and measurement. Next, a theoretical framework is presented, together with a comparison of computed and experimental data. Finally, some control aspects are discussed, together with illustration that the major design objective of LAMSTF - a controlled 360 deg rotation about the vertical axis, has been accomplished.

Zero Launch Mass 3D printer

NASA Image and Video Library

2018-05-01

Packing light is the idea behind the Zero Launch Mass 3-D Printer. Instead of loading up on heavy building supplies, a large scale 3-D printer capable of using recycled plastic waste and dirt at the destination as construction material would save mass and money when launching robotic precursor missions to build infrastructure on the Moon or Mars in preparation for human habitation. To make this a reality, Nathan Gelino, a researcher engineer with NASA’s Swamp Works at Kennedy Space Center, measured the temperature of a test specimen from the 3-D printer Tuesday as an early step in characterizing printed material strength properties. Material temperature plays a large role in the strength of bonds between layers.

History of the Army Ground Forces. Study Number 24. History of the Mountain Training Center

DTIC Science & Technology

1948-01-01

yaws, pius the knowledge of mevoral experienced mountaineers and skiers in the Office of the Quartermster General. On 20 May 1943 the Mountain and... skier ? Or will a mini- of knowledge and proficiency be sufficient? These are the questions that tad to be answered before the large-scale trainiag of...the prerogatives of Army co-nand were subordinated to the superior knowledge and skills of the mountaineering experts who had come into the Army7

Evaluation of a metal shear web selectively reinforced with filamentary composites for space shuttle application. Phase 2: summary report: Shear web component fabrication

NASA Technical Reports Server (NTRS)

Laakso, J. H.; Smith, D. D.; Zimmerman, D. K.

1973-01-01

The fabrication of two shear web test elements and three large scale shear web test components are reported. In addition, the fabrication of test fixtures for the elements and components is described. The center-loaded beam test fixtures were configured to have a test side and a dummy or permanent side. The test fixtures were fabricated from standard extruded aluminum sections and plates and were designed to be reuseable.

Epigenome data release: a participant-centered approach to privacy protection.

PubMed

Dyke, Stephanie O M; Cheung, Warren A; Joly, Yann; Ammerpohl, Ole; Lutsik, Pavlo; Rothstein, Mark A; Caron, Maxime; Busche, Stephan; Bourque, Guillaume; Rönnblom, Lars; Flicek, Paul; Beck, Stephan; Hirst, Martin; Stunnenberg, Henk; Siebert, Reiner; Walter, Jörn; Pastinen, Tomi

2015-07-17

Large-scale epigenome mapping by the NIH Roadmap Epigenomics Project, the ENCODE Consortium and the International Human Epigenome Consortium (IHEC) produces genome-wide DNA methylation data at one base-pair resolution. We examine how such data can be made open-access while balancing appropriate interpretation and genomic privacy. We propose guidelines for data release that both reduce ambiguity in the interpretation of open-access data and limit immediate access to genetic variation data that are made available through controlled access.

Analysis of terrestrial conditions and dynamics

NASA Technical Reports Server (NTRS)

Goward, S. N. (Principal Investigator)

1984-01-01

Land spectral reflectance properties for selected locations, including the Goddard Space Flight Center, the Wallops Flight Facility, a MLA test site in Cambridge, Maryland, and an acid test site in Burlington, Vermont, were measured. Methods to simulate the bidirectional reflectance properties of vegetated landscapes and a data base for spatial resolution were developed. North American vegetation patterns observed with the Advanced Very High Resolution Radiometer were assessed. Data and methods needed to model large-scale vegetation activity with remotely sensed observations and climate data were compiled.

Evolution of the Tropical Cyclone Integrated Data Exchange And Analysis System (TC-IDEAS)

NASA Technical Reports Server (NTRS)

Turk, J.; Chao, Y.; Haddad, Z.; Hristova-Veleva, S.; Knosp, B.; Lambrigtsen, B.; Li, P.; Licata, S.; Poulsen, W.; Su, H.;

Management Science Relations for Evaluation and Management Accountability

DTIC Science & Technology

1979-05-01

report i ,C ssI Ied 7 a G .C , -I T I ’ Coporate artho) 2a. P , R r SECtrP Ta (LASSI -1C A Center for Cybernetic Studies Unclassified The University of...efficiency of not-for-profit entities . An illustra- tive application to a recently completed large-scale social experiment in edu- cating...agement amd managed entities . As indicative of some of these differences, we may here, for the moment, distinguish between "pure predictioas" and

An integrated circuit floating point accumulator

NASA Technical Reports Server (NTRS)

Goldsmith, T. C.

1977-01-01

Goddard Space Flight Center has developed a large scale integrated circuit (type 623) which can perform pulse counting, storage, floating point compression, and serial transmission, using a single monolithic device. Counts of 27 or 19 bits can be converted to transmitted values of 12 or 8 bits respectively. Use of the 623 has resulted in substantial savaings in weight, volume, and dollar resources on at least 11 scientific instruments to be flown on 4 NASA spacecraft. The design, construction, and application of the 623 are described.

The Center for Astrophysics Redshift Survey - Recent results

NASA Technical Reports Server (NTRS)

Geller, Margaret J.; Huchra, John P.

1989-01-01

Six strips of the CfA redshift survey extension are now complete. The data continue to support a picture in which galaxies are on thin sheets which nearly surround vast low-density voids. The largest structures are comparable with the extent of the survey. Voids like the one in Bootes are a common feature of the large-scale distribution of galaxies. The issue of fair samples of the galaxy distribution is discussed, examining statistical measures of the galaxy distribution including the two-point correlation functions.