Sample records for central capacity sharing

  1. Testing the Predictions of the Central Capacity Sharing Model

    ERIC Educational Resources Information Center

    Tombu, Michael; Jolicoeur, Pierre

    2005-01-01

    The divergent predictions of 2 models of dual-task performance are investigated. The central bottleneck and central capacity sharing models argue that a central stage of information processing is capacity limited, whereas stages before and after are capacity free. The models disagree about the nature of this central capacity limitation. The…

  2. Dual-task interference with equal task emphasis: graded capacity sharing or central postponement?

    NASA Technical Reports Server (NTRS)

    Ruthruff, Eric; Pashler, Harold E.; Hazeltine, Eliot

    2003-01-01

    Most studies using the psychological refractory period (PRP) design suggest that dual-task performance is limited by a central bottleneck. Because subjects are usually told to emphasize Task 1, however, the bottleneck might reflect a strategic choice rather than a structural limitation. To evaluate the possibility that central operations can proceed in parallel, albeit with capacity limitations, we conducted two dual-task experiments with equal task emphasis. In both experiments, subjects tended to either group responses together or respond to one task well before the other. In addition, stimulus-response compatibility effects were roughly constant across stimulus onset asynchronies (SOAs). At the short SOA, compatibility effects also carried over onto response times for the other task. This pattern of results is difficult to reconcile with the possibility that subjects share capacity roughly equally between simultaneous central operations. However, this pattern is consistent with the existence of a structural central bottleneck.

  3. IVHS Institutional Issues And Case Studies: Westchester Commuter Central Case Study

    DOT National Transportation Integrated Search

    1997-01-01

    Shared resource projects are public-private arrangements that involve sharing public property such as rights-of-way and private resources such as telecommunications capacity and expertise. Typically, private telecommunications providers are granted a...

  4. "Come and See": An Existential Approach to Received Wisdom

    ERIC Educational Resources Information Center

    Frendo, Anthony J.

    2007-01-01

    Experience and community have always played a central role in the construction of knowledge. It is upon reflecting on everyday life experiences, and sharing these experiences and reflections with one's community, that knowledge is filtered and transformed into wisdom. The same acts of reflection and sharing are part of human's capacity to…

  5. A Healthy Communities Initiative in Rural Alberta: Building Rural Capacity for Health.

    ERIC Educational Resources Information Center

    GermAnn, Kathy; Smith, Neale; Littlejohns, Lori Baugh

    Efforts of health professionals are shifting away from programs that "deliver health" toward those that build the capacity of communities to work together to create healthy places. The Healthy Communities Initiative (HCI) is a community development model in central Alberta (Canada) that involves the creation of a widely shared vision of…

  6. Discrete Resource Allocation in Visual Working Memory

    ERIC Educational Resources Information Center

    Barton, Brian; Ester, Edward F.; Awh, Edward

    2009-01-01

    Are resources in visual working memory allocated in a continuous or a discrete fashion? On one hand, flexible resource models suggest that capacity is determined by a central resource pool that can be flexibly divided such that items of greater complexity receive a larger share of resources. On the other hand, if capacity in working memory is…

  7. Distributed control system for parallel-connected DC boost converters

    DOEpatents

    Goldsmith, Steven

    2017-08-15

    The disclosed invention is a distributed control system for operating a DC bus fed by disparate DC power sources that service a known or unknown load. The voltage sources vary in v-i characteristics and have time-varying, maximum supply capacities. Each source is connected to the bus via a boost converter, which may have different dynamic characteristics and power transfer capacities, but are controlled through PWM. The invention tracks the time-varying power sources and apportions their power contribution while maintaining the DC bus voltage within the specifications. A central digital controller solves the steady-state system for the optimal duty cycle settings that achieve a desired power supply apportionment scheme for a known or predictable DC load. A distributed networked control system is derived from the central system that utilizes communications among controllers to compute a shared estimate of the unknown time-varying load through shared bus current measurements and bus voltage measurements.

  8. Improvement of multiprocessing performance by using optical centralized shared bus

    NASA Astrophysics Data System (ADS)

    Han, Xuliang; Chen, Ray T.

    2004-06-01

    With the ever-increasing need to solve larger and more complex problems, multiprocessing is attracting more and more research efforts. One of the challenges facing the multiprocessor designers is to fulfill in an effective manner the communications among the processes running in parallel on multiple multiprocessors. The conventional electrical backplane bus provides narrow bandwidth as restricted by the physical limitations of electrical interconnects. In the electrical domain, in order to operate at high frequency, the backplane topology has been changed from the simple shared bus to the complicated switched medium. However, the switched medium is an indirect network. It cannot support multicast/broadcast as effectively as the shared bus. Besides the additional latency of going through the intermediate switching nodes, signal routing introduces substantial delay and considerable system complexity. Alternatively, optics has been well known for its interconnect capability. Therefore, it has become imperative to investigate how to improve multiprocessing performance by utilizing optical interconnects. From the implementation standpoint, the existing optical technologies still cannot fulfill the intelligent functions that a switch fabric should provide as effectively as their electronic counterparts. Thus, an innovative optical technology that can provide sufficient bandwidth capacity, while at the same time, retaining the essential merits of the shared bus topology, is highly desirable for the multiprocessing performance improvement. In this paper, the optical centralized shared bus is proposed for use in the multiprocessing systems. This novel optical interconnect architecture not only utilizes the beneficial characteristics of optics, but also retains the desirable properties of the shared bus topology. Meanwhile, from the architecture standpoint, it fits well in the centralized shared-memory multiprocessing scheme. Therefore, a smooth migration with substantial multiprocessing performance improvement is expected. To prove the technical feasibility from the architecture standpoint, a conceptual emulation of the centralized shared-memory multiprocessing scheme is demonstrated on a generic PCI subsystem with an optical centralized shared bus.

  9. The vision in supervision: transference-countertransference dynamics and disclosure in the supervision relationship.

    PubMed

    Coburn, W J

    1997-01-01

    The centrality of the supervision experience in the development of the supervisee's personal and professional capacities is addressed. The supervision relationship and process are explored in light of the potential effects of transference-countertransference configurations of supervisor and supervisee. Parallels between supervision and treatment are highlighted. The importance of developing and utilizing the capacity for reflectivity is reviewed, as is the impact of supervisee nondisclosure to supervisor. The direct use of countertransference experiences in the context of supervision is explored, and the centrality of self-disclosure is highlighted. It is recommended that supervisor and supervisee remain receptive to exploring these experiences in the service of developing a shared subjective sense of the patient, of increasing the supervisee's capacity to treat his or her patient, and of providing the supervisee with a novel, growth-enhancing relationship.

  10. Leading with Intent: Cultivating Community Conversation to Create Shared Understanding

    ERIC Educational Resources Information Center

    Marsh, Scott; Waniganayake, Manjula; De Nobile, John J.

    2016-01-01

    School improvement is a central focus for school leaders. Whilst measures such as high-stakes testing and other government accountability agendas have at times marred the discourse of school improvement, how schools develop their capacity to ultimately improve the core business of student learning remains important. As an extensive area of…

  11. Life, Liberty, and the Pursuit of . . .

    ERIC Educational Resources Information Center

    Eberly, Rosa A.; Serber, Brad

    2013-01-01

    With the hope of inspiring readers to reimagine the centrality of general education in constituting young adult capacities to create and sustain collective self-governance, this essay describes two courses and one activity built around public problems. General education viewed as a human right as well as a shared responsibility can thus serve as a…

  12. U.S.-India Security Burden-Sharing? The Potential for Coordinated Capacity-Building in the Indian Ocean

    DTIC Science & Technology

    2013-04-01

    their country’s eco - nomic image and prospects. Regardless of terminology, many Bang- ladeshi officers and experts express a desire to coordinate on...put on the back burner for short-term considerations. 2014 Indian central elections – A new Prime Minister in India could inject a very different tone

  13. Exploring the Cognitive Foundations of the Shared Attention Mechanism: Evidence for a Relationship Between Self-Categorization and Shared Attention Across the Autism Spectrum.

    PubMed

    Skorich, Daniel P; Gash, Tahlia B; Stalker, Katie L; Zheng, Lidan; Haslam, S Alexander

    2017-05-01

    The social difficulties of autism spectrum disorder (ASD) are typically explained as a disruption in the Shared Attention Mechanism (SAM) sub-component of the theory of mind (ToM) system. In the current paper, we explore the hypothesis that SAM's capacity to construct the self-other-object relations necessary for shared-attention arises from a self-categorization process, which is weaker among those with more autistic-like traits. We present participants with self-categorization and shared-attention tasks, and measure their autism-spectrum quotient (AQ). Results reveal a negative relationship between AQ and shared-attention, via self-categorization, suggesting a role for self-categorization in the disruption in SAM seen in ASD. Implications for intervention, and for a ToM model in which weak central coherence plays a role are discussed.

  14. Stakeholders' views of shared learning models in general practice: a national survey.

    PubMed

    van de Mortel, Thea; Silberberg, Peter; Ahern, Christine; Pit, Sabrina

    2014-09-01

    The number of learners requiring general practice placements creates supervisory capacity constraints. This research examined how a shared learning model may affect training capacity. The number of learners requiring general practice placements creates supervisory capacity constraints. This research examined how a shared learning model may affect training capacity. A total of 1122 surveys were completed: 75% of learners had participated in shared learning; 25% of multi-level learner practices were not using shared learning. Learners were positive about shared learning (4.3-4.4/5), considering it an effective way to learn that created training capacity (4.1-4.2/5). 79-88% of learners preferred a mixture of one-to-one teaching and shared learning. Supervisors thought shared learning was more cost- and time-efficient, and created training capacity (4.3-4.4/5). Shared learning models have the potential to increase GP training capacity. Many practices are not utilising shared learning, representing capacity loss. Regional training providers should emphasise positive aspects of shared learning to facilitate uptake.

  15. Motor-cognitive dual-task performance: effects of a concurrent motor task on distinct components of visual processing capacity.

    PubMed

    Künstler, E C S; Finke, K; Günther, A; Klingner, C; Witte, O; Bublak, P

    2018-01-01

    Dual tasking, or the simultaneous execution of two continuous tasks, is frequently associated with a performance decline that can be explained within a capacity sharing framework. In this study, we assessed the effects of a concurrent motor task on the efficiency of visual information uptake based on the 'theory of visual attention' (TVA). TVA provides parameter estimates reflecting distinct components of visual processing capacity: perceptual threshold, visual processing speed, and visual short-term memory (VSTM) storage capacity. Moreover, goodness-of-fit values and bootstrapping estimates were derived to test whether the TVA-model is validly applicable also under dual task conditions, and whether the robustness of parameter estimates is comparable in single- and dual-task conditions. 24 subjects of middle to higher age performed a continuous tapping task, and a visual processing task (whole report of briefly presented letter arrays) under both single- and dual-task conditions. Results suggest a decline of both visual processing capacity and VSTM storage capacity under dual-task conditions, while the perceptual threshold remained unaffected by a concurrent motor task. In addition, goodness-of-fit values and bootstrapping estimates support the notion that participants processed the visual task in a qualitatively comparable, although quantitatively less efficient way under dual-task conditions. The results support a capacity sharing account of motor-cognitive dual tasking and suggest that even performing a relatively simple motor task relies on central attentional capacity that is necessary for efficient visual information uptake.

  16. Shared Decision-Making and Patient Empowerment in Preventive Cardiology.

    PubMed

    Kambhampati, Swetha; Ashvetiya, Tamara; Stone, Neil J; Blumenthal, Roger S; Martin, Seth S

    2016-05-01

    Shared decision-making, central to evidence-based medicine and good patient care, begins and ends with the patient. It is the process by which a clinician and a patient jointly make a health decision after discussing options, potential benefits and harms, and considering the patient's values and preferences. Patient empowerment is crucial to shared decision-making and occurs when a patient accepts responsibility for his or her health. They can then learn to solve their own problems with information and support from professionals. Patient empowerment begins with the provider acknowledging that patients are ultimately in control of their care and aims to increase a patient's capacity to think critically and make autonomous, informed decisions about their health. This article explores the various components of shared decision-making in scenarios such as hypertension and hyperlipidemia, heart failure, and diabetes. It explores barriers and the potential for improving medication adherence, disease awareness, and self-management of chronic disease.

  17. Multi-dimension and Comprehensive Assessment on the Utilizing and Sharing of Regional Large-Scale Scientific Equipment

    PubMed Central

    Li, Chen; Yongbo, Lv; Chi, Chen

    2015-01-01

    Based on the data from 30 provincial regions in China, an assessment and empirical analysis was carried out on the utilizing and sharing of the large-scale scientific equipment with a comprehensive assessment model established on the three dimensions, namely, equipment, utilization and sharing. The assessment results were interpreted in light of relevant policies. The results showed that on the whole, the overall development level in the provincial regions in eastern and central China is higher than that in western China. This is mostly because of the large gap among the different provincial regions with respect to the equipped level. But in terms of utilizing and sharing, some of the Western provincial regions, such as Ningxia, perform well, which is worthy of our attention. Policy adjustment targeting at the differentiation, elevation of the capacity of the equipment management personnel, perfection of the sharing and cooperation platform, and the promotion of the establishment of open sharing funds, are all important measures to promote the utilization and sharing of the large-scale scientific equipment and to narrow the gap among different regions. PMID:25937850

  18. Promoting evaluation capacity building in a complex adaptive system.

    PubMed

    Lawrenz, Frances; Kollmann, Elizabeth Kunz; King, Jean A; Bequette, Marjorie; Pattison, Scott; Nelson, Amy Grack; Cohn, Sarah; Cardiel, Christopher L B; Iacovelli, Stephanie; Eliou, Gayra Ostgaard; Goss, Juli; Causey, Lauren; Sinkey, Anne; Beyer, Marta; Francisco, Melanie

    2018-04-10

    This study provides results from an NSF funded, four year, case study about evaluation capacity building in a complex adaptive system, the Nanoscale Informal Science Education Network (NISE Net). The results of the Complex Adaptive Systems as a Model for Network Evaluations (CASNET) project indicate that complex adaptive system concepts help to explain evaluation capacity building in a network. The NISE Network was found to be a complex learning system that was supportive of evaluation capacity building through feedback loops that provided for information sharing and interaction. Participants in the system had different levels of and sources of evaluation knowledge. To be successful at building capacity, the system needed to have a balance between both centralized and decentralized control, coherence, redundancy, and diversity. Embeddedness of individuals within the system also provided support and moved the capacity of the system forward. Finally, success depended on attention being paid to the control of resources. Implications of these findings are discussed. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Advancing the Interdisciplinary Collaborative Health Team Model: Applying Democratic Professionalism, Implementation Science, and Therapeutic Alliance to Enact Social Justice Practice.

    PubMed

    Murphy, Nancy

    2015-01-01

    This essay reframes the interdisciplinary collaborative health team model by proposing the application of 3 foundational pillars-democratic professionalism, implementation science, and therapeutic alliance to advance this practice. The aim was to address challenges to the model, enhance their functional capacity, and explicate and enact social justice practices to affect individual health outcomes while simultaneously addressing health inequities. The pillars are described and examples from the author's dissertation research illustrate how the pillars were used to bring about action. Related theories, models, and frameworks that have negotiation, capacity building, collaboration, and knowledge/task/power sharing as central concepts are presented under each of the pillars.

  20. Shared filtering processes link attentional and visual short-term memory capacity limits.

    PubMed

    Bettencourt, Katherine C; Michalka, Samantha W; Somers, David C

    2011-09-30

    Both visual attention and visual short-term memory (VSTM) have been shown to have capacity limits of 4 ± 1 objects, driving the hypothesis that they share a visual processing buffer. However, these capacity limitations also show strong individual differences, making the degree to which these capacities are related unclear. Moreover, other research has suggested a distinction between attention and VSTM buffers. To explore the degree to which capacity limitations reflect the use of a shared visual processing buffer, we compared individual subject's capacities on attentional and VSTM tasks completed in the same testing session. We used a multiple object tracking (MOT) and a VSTM change detection task, with varying levels of distractors, to measure capacity. Significant correlations in capacity were not observed between the MOT and VSTM tasks when distractor filtering demands differed between the tasks. Instead, significant correlations were seen when the tasks shared spatial filtering demands. Moreover, these filtering demands impacted capacity similarly in both attention and VSTM tasks. These observations fail to support the view that visual attention and VSTM capacity limits result from a shared buffer but instead highlight the role of the resource demands of underlying processes in limiting capacity.

  1. Improving nutrition surveillance and public health research in Central and Eastern Europe/Balkan Countries using the Balkan Food Platform and dietary tools.

    PubMed

    Gurinović, Mirjana; Milešević, Jelena; Novaković, Romana; Kadvan, Agnes; Djekić-Ivanković, Marija; Šatalić, Zvonimir; Korošec, Mojca; Spiroski, Igor; Ranić, Marija; Dupouy, Eleonora; Oshaug, Arne; Finglas, Paul; Glibetić, Maria

    2016-02-15

    The objective of this paper is to share experience and provide updated information on Capacity Development in the Central and Eastern Europe/Balkan Countries (CEE/BC) region relevant to public health nutrition, particularly in creation of food composition databases (FCDBs), applying dietary intake assessment and monitoring tools, and harmonizing methodology for nutrition surveillance. Balkan Food Platform was established by a Memorandum of Understanding among EuroFIR AISBL, Institute for Medical Research, Belgrade, Capacity Development Network in Nutrition in CEE - CAPNUTRA and institutions from nine countries in the region. Inventory on FCDB status identified lack of harmonized and standardized research tools. To strengthen harmonization in CEE/BC in line with European research trends, the Network members collaborated in development of a Regional FCDB, using web-based food composition data base management software following EuroFIR standards. Comprehensive nutrition assessment and planning tool - DIET ASSESS & PLAN could enable synchronization of nutrition surveillance across countries. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Controlled replication: reduce the capacity occupied by redundant replicas in tiled chip multiprocessors

    NASA Astrophysics Data System (ADS)

    Li, Hao; Xie, Lunguo

    2013-03-01

    The design of cache system for Chip Multiprocessor (CMP) face many challenges because future CMPs will have more cores and greater on-chip cache capacity. There are two base design schemes about L2 cache: private scheme in which each L2 slice is treated as a private L2 cache and shared scheme in which all L2 slices are treated as a large L2 cache shared by all cores. Private caches provide the lowest hit latency but reduce the total effective cache capacity. A shared L2 cache increases the effective cache capacity but has long hit latencies when data is on a remote tile. This paper present a new Controlled Replication (CR) policy to reduce the capacities occupied by redundant shared replicas. the new CR policy increases the effective capacity than victim replication scheme and has lower hit latency than shared scheme. We evaluate the various schemes using full-system simulation of parallel applications. Results show that CR reduces the average memory access latency of shared scheme by an average of 13%, providing better overall performance than victim replication and shared schemes.

  3. Effect of infrastructure design on commons dilemmas in social-ecological system dynamics.

    PubMed

    Yu, David J; Qubbaj, Murad R; Muneepeerakul, Rachata; Anderies, John M; Aggarwal, Rimjhim M

    2015-10-27

    The use of shared infrastructure to direct natural processes for the benefit of humans has been a central feature of human social organization for millennia. Today, more than ever, people interact with one another and the environment through shared human-made infrastructure (the Internet, transportation, the energy grid, etc.). However, there has been relatively little work on how the design characteristics of shared infrastructure affect the dynamics of social-ecological systems (SESs) and the capacity of groups to solve social dilemmas associated with its provision. Developing such understanding is especially important in the context of global change where design criteria must consider how specific aspects of infrastructure affect the capacity of SESs to maintain vital functions in the face of shocks. Using small-scale irrigated agriculture (the most ancient and ubiquitous example of public infrastructure systems) as a model system, we show that two design features related to scale and the structure of benefit flows can induce fundamental changes in qualitative behavior, i.e., regime shifts. By relating the required maintenance threshold (a design feature related to infrastructure scale) to the incentives facing users under different regimes, our work also provides some general guidance on determinants of robustness of SESs under globalization-related stresses.

  4. Effect of infrastructure design on commons dilemmas in social−ecological system dynamics

    PubMed Central

    Yu, David J.; Qubbaj, Murad R.; Muneepeerakul, Rachata; Anderies, John M.; Aggarwal, Rimjhim M.

    2015-01-01

    The use of shared infrastructure to direct natural processes for the benefit of humans has been a central feature of human social organization for millennia. Today, more than ever, people interact with one another and the environment through shared human-made infrastructure (the Internet, transportation, the energy grid, etc.). However, there has been relatively little work on how the design characteristics of shared infrastructure affect the dynamics of social−ecological systems (SESs) and the capacity of groups to solve social dilemmas associated with its provision. Developing such understanding is especially important in the context of global change where design criteria must consider how specific aspects of infrastructure affect the capacity of SESs to maintain vital functions in the face of shocks. Using small-scale irrigated agriculture (the most ancient and ubiquitous example of public infrastructure systems) as a model system, we show that two design features related to scale and the structure of benefit flows can induce fundamental changes in qualitative behavior, i.e., regime shifts. By relating the required maintenance threshold (a design feature related to infrastructure scale) to the incentives facing users under different regimes, our work also provides some general guidance on determinants of robustness of SESs under globalization-related stresses. PMID:26460043

  5. Design of an Input-Parallel Output-Parallel LLC Resonant DC-DC Converter System for DC Microgrids

    NASA Astrophysics Data System (ADS)

    Juan, Y. L.; Chen, T. R.; Chang, H. M.; Wei, S. E.

    2017-11-01

    Compared with the centralized power system, the distributed modularized power system is composed of several power modules with lower power capacity to provide a totally enough power capacity for the load demand. Therefore, the current stress of the power components in each module can then be reduced, and the flexibility of system setup is also enhanced. However, the parallel-connected power modules in the conventional system are usually controlled to equally share the power flow which would result in lower efficiency in low loading condition. In this study, a modular power conversion system for DC micro grid is developed with 48 V dc low voltage input and 380 V dc high voltage output. However, in the developed system control strategy, the numbers of power modules enabled to share the power flow is decided according to the output power at lower load demand. Finally, three 350 W power modules are constructed and parallel-connected to setup a modular power conversion system. From the experimental results, compared with the conventional system, the efficiency of the developed power system in the light loading condition is greatly improved. The modularized design of the power system can also decrease the power loss ratio to the system capacity.

  6. Large-Capacity Three-Party Quantum Digital Secret Sharing Using Three Particular Matrices Coding

    NASA Astrophysics Data System (ADS)

    Lai, Hong; Luo, Ming-Xing; Pieprzyk, Josef; Tao, Li; Liu, Zhi-Ming; Orgun, Mehmet A.

    2016-11-01

    In this paper, we develop a large-capacity quantum digital secret sharing (QDSS) scheme, combined the Fibonacci- and Lucas-valued orbital angular momentum (OAM) entanglement with the recursive Fibonacci and Lucas matrices. To be exact, Alice prepares pairs of photons in the Fibonacci- and Lucas-valued OAM entangled states, and then allocates them to two participants, say, Bob and Charlie, to establish the secret key. Moreover, the available Fibonacci and Lucas values from the matching entangled states are used as the seed for generating the Fibonacci and Lucas matrices. This is achieved because the entries of the Fibonacci and Lucas matrices are recursive. The secret key can only be obtained jointly by Bob and Charlie, who can further recover the secret. Its security is based on the facts that nonorthogonal states are indistinguishable, and Bob or Charlie detects a Fibonacci number, there is still a twofold uncertainty for Charlie' (Bob') detected value. Supported by the Fundamental Research Funds for the Central Universities under Grant No. XDJK2016C043 and the Doctoral Program of Higher Education under Grant No. SWU115091, the National Natural Science Foundation of China under Grant No. 61303039, the Fundamental Research Funds for the Central Universities under Grant No. XDJK2015C153 and the Doctoral Program of Higher Education under Grant No. SWU114112, and the Financial Support the 1000-Plan of Chongqing by Southwest University under Grant No. SWU116007

  7. Relational learning and interprofessional practice: transforming health education for the 21st century.

    PubMed

    Konrad, Shelley Cohen; Browning, David M

    2012-01-01

    Theories and traditions emphasizing the centrality of caring have guided the evolution of the healthcare professions. In contemporary practice, creating a therapeutic context in which healing can occur relies not just on the caring dispositions of individual clinicians, but also on the collective relational capacities of interprofessional healthcare teams. This article describes the intersection and complementarity of relational and interprofessional learning approaches to health education, provides exemplars of shared learning models and discusses the benefits and obstacles to integrating relational and interprofessional philosophies into real world practice.

  8. Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseases

    PubMed Central

    Allarakhia, Minna

    2013-01-01

    Repurposing has the objective of targeting existing drugs and failed, abandoned, or yet-to-be-pursued clinical candidates to new disease areas. The open-source model permits for the sharing of data, resources, compounds, clinical molecules, small libraries, and screening platforms to cost-effectively advance old drugs and/or candidates into clinical re-development. Clearly, at the core of drug-repurposing activities is collaboration, in many cases progressing beyond the open sharing of resources, technology, and intellectual property, to the sharing of facilities and joint program development to foster drug-repurposing human-capacity development. A variety of initiatives under way for drug repurposing, including those targeting rare and neglected diseases, are discussed in this review and provide insight into the stakeholders engaged in drug-repurposing discovery, the models of collaboration used, the intellectual property-management policies crafted, and human capacity developed. In the case of neglected tropical diseases, it is suggested that the development of human capital be a central aspect of drug-repurposing programs. Open-source models can support human-capital development through collaborative data generation, open compound access, open and collaborative screening, preclinical and possibly clinical studies. Given the urgency of drug development for neglected tropical diseases, the review suggests elements from current repurposing programs be extended to the neglected tropical diseases arena. PMID:23966771

  9. Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseases.

    PubMed

    Allarakhia, Minna

    2013-01-01

    Repurposing has the objective of targeting existing drugs and failed, abandoned, or yet-to-be-pursued clinical candidates to new disease areas. The open-source model permits for the sharing of data, resources, compounds, clinical molecules, small libraries, and screening platforms to cost-effectively advance old drugs and/or candidates into clinical re-development. Clearly, at the core of drug-repurposing activities is collaboration, in many cases progressing beyond the open sharing of resources, technology, and intellectual property, to the sharing of facilities and joint program development to foster drug-repurposing human-capacity development. A variety of initiatives under way for drug repurposing, including those targeting rare and neglected diseases, are discussed in this review and provide insight into the stakeholders engaged in drug-repurposing discovery, the models of collaboration used, the intellectual property-management policies crafted, and human capacity developed. In the case of neglected tropical diseases, it is suggested that the development of human capital be a central aspect of drug-repurposing programs. Open-source models can support human-capital development through collaborative data generation, open compound access, open and collaborative screening, preclinical and possibly clinical studies. Given the urgency of drug development for neglected tropical diseases, the review suggests elements from current repurposing programs be extended to the neglected tropical diseases arena.

  10. A Novel Optimal Joint Resource Allocation Method in Cooperative Multicarrier Networks: Theory and Practice

    PubMed Central

    Gao, Yuan; Zhou, Weigui; Ao, Hong; Chu, Jian; Zhou, Quan; Zhou, Bo; Wang, Kang; Li, Yi; Xue, Peng

    2016-01-01

    With the increasing demands for better transmission speed and robust quality of service (QoS), the capacity constrained backhaul gradually becomes a bottleneck in cooperative wireless networks, e.g., in the Internet of Things (IoT) scenario in joint processing mode of LTE-Advanced Pro. This paper focuses on resource allocation within capacity constrained backhaul in uplink cooperative wireless networks, where two base stations (BSs) equipped with single antennae serve multiple single-antennae users via multi-carrier transmission mode. In this work, we propose a novel cooperative transmission scheme based on compress-and-forward with user pairing to solve the joint mixed integer programming problem. To maximize the system capacity under the limited backhaul, we formulate the joint optimization problem of user sorting, subcarrier mapping and backhaul resource sharing among different pairs (subcarriers for users). A novel robust and efficient centralized algorithm based on alternating optimization strategy and perfect mapping is proposed. Simulations show that our novel method can improve the system capacity significantly under the constraint of the backhaul resource compared with the blind alternatives. PMID:27077865

  11. A Framework for Shared Leadership.

    ERIC Educational Resources Information Center

    Lambert, Linda

    2002-01-01

    Asserts that principals can improve student learning by sharing the leadership of instruction with teachers and parents thereby building leadership capacity. Describes characteristics of schools with high leadership capacity. Provides examples of building leadership capacity through the use of study groups, action-research teams, and leadership…

  12. Central African Field Epidemiology and Laboratory Training Program: building and strengthening regional workforce capacity in public health.

    PubMed

    Andze, Gervais Ondobo; Namsenmo, Abel; Illunga, Benoit Kebella; Kazambu, Ditu; Delissaint, Dieula; Kuaban, Christopher; Mbopi-Kéou, Francois-Xavier; Gabsa, Wilfred; Mulumba, Leopold; Bangamingo, Jean Pierre; Ngulefac, John; Dahlke, Melissa; Mukanga, David; Nsubuga, Peter

    2011-01-01

    The Central African Field Epidemiology and Laboratory Training Program (CAFELTP) is a 2-year public health leadership capacity building training program. It was established in October 2010 to enhance capacity for applied epidemiology and public health laboratory services in three countries: Cameroon, Central African Republic, and the Democratic Republic of Congo. The aim of the program is to develop a trained public health workforce to assure that acute public health events are detected, investigated, and responded to quickly and effectively. The program consists of 25% didactic and 75% practical training (field based activities). Although the program is still in its infancy, the residents have already responded to six outbreak investigations in the region, evaluated 18 public health surveillance systems and public health programs, and completed 18 management projects. Through these various activities, information is shared to understand similarities and differences in the region leading to new and innovative approaches in public health. The program provides opportunities for regional and international networking in field epidemiology and laboratory activities, and is particularly beneficial for countries that may not have the immediate resources to host an individual country program. Several of the trainees from the first cohort already hold leadership positions within the ministries of health and national laboratories, and will return to their assignments better equipped to face the public health challenges in the region. They bring with them knowledge, practical training, and experiences gained through the program to shape the future of the public health landscape in their countries.

  13. Central African Field Epidemiology and Laboratory Training Program: building and strengthening regional workforce capacity in public health

    PubMed Central

    Ondobo Andze, Gervais; Namsenmo, Abel; Kebella Illunga, Benoit; Kazambu, Ditu; Delissaint, Dieula; Kuaban, Christopher; Mbopi-Kéou, Francois-Xavier; Gabsa, Wilfred; Mulumba, Leopold; Pierre Bangamingo, Jean; Ngulefac, John; Dahlke, Melissa; Mukanga, David; Nsubuga, Peter

    2011-01-01

    The Central African Field Epidemiology and Laboratory Training Program (CAFELTP) is a 2-year public health leadership capacity building training program. It was established in October 2010 to enhance capacity for applied epidemiology and public health laboratory services in three countries: Cameroon, Central African Republic, and the Democratic Republic of Congo. The aim of the program is to develop a trained public health workforce to assure that acute public health events are detected, investigated, and responded to quickly and effectively. The program consists of 25% didactic and 75% practical training (field based activities). Although the program is still in its infancy, the residents have already responded to six outbreak investigations in the region, evaluated 18 public health surveillance systems and public health programs, and completed 18 management projects. Through these various activities, information is shared to understand similarities and differences in the region leading to new and innovative approaches in public health. The program provides opportunities for regional and international networking in field epidemiology and laboratory activities, and is particularly beneficial for countries that may not have the immediate resources to host an individual country program. Several of the trainees from the first cohort already hold leadership positions within the ministries of health and national laboratories, and will return to their assignments better equipped to face the public health challenges in the region. They bring with them knowledge, practical training, and experiences gained through the program to shape the future of the public health landscape in their countries. PMID:22359692

  14. 77 FR 56209 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ..., Lebanon, Missouri, to acquire additional voting shares of Central Missouri Shares, Inc., and thereby indirectly acquire additional voting shares of Central Missouri Bank, Inc., both of Lebanon, Missouri. Board...

  15. Team-building activities as strategies for improving community-university partnerships: lessons learned from Nuestro Futuro Saludable.

    PubMed

    Ndulue, Uchenna; Peréa, Flavia C; Kayou, Bashier; Martinez, Linda Sprague

    2012-01-01

    Collaboration characterized by mutual capacity building, asset sharing, and tangible outcomes that work to further health equity are central tenets of community-based participatory (CBPR) approaches to research. Such efforts require the establishment, development, and maintenance of trusting relationships between community and institutional stakeholders. The objective of the strategies discussed here was to strengthen a community-academic partnership by facilitating communication and empowering project partners. Team-building activities and experiential exercises were intentionally utilized with project stakeholders to clarify roles and responsibilities, provide alternative avenues for authentic communication, and share power. Team-building activities can be effective in promoting CBPR partnerships when utilized appropriately. Through the course of the partnership building process, best practices emerged for utilizing experiential learning exercises to enhance partnership dynamics. Team-building activities provide a useful tool for developing supportive environments that encourage open dialogue.

  16. Evaluation of transboundary environmental issues in Central Europe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Engi, D.; Kapustka, L.A.; Williams, B.A.

    1997-05-01

    Central Europe has experienced environmental degradation for hundreds of years. The proximity of countries, their shared resources, and transboundary movement of environmental pollution, create the potential for regional environmental strife. The goal of this project was to identify the sources and sinks of environmental pollution in Central Europe and evaluate the possible impact of transboundary movement of pollution on the countries of Central Europe. In meeting the objectives of identifying sources of contaminants, determining transboundary movement of contaminants, and assessing socio-economic implications, large quantities of disparate data were examined. To facilitate use of the data, the authors refined mapping proceduresmore » that enable processing information from virtually any map or spreadsheet data that can be geo-referenced. Because the procedure is freed from a priori constraints of scale that confound most Geographical Information Systems, they have the capacity to generate new projections and apply sophisticated statistical analyses to the data. The analysis indicates substantial environmental problems. While transboundary pollution issues may spawn conflict among the Central European countries and their neighbors, it appears that common environmental problems facing the entire region have had the effect of bringing the countries together, even though opportunities for deteriorating relationships may still arise.« less

  17. Central and Peripheral Components of Working Memory Storage

    PubMed Central

    Cowan, Nelson; Saults, J. Scott; Blume, Christopher L.

    2014-01-01

    This study re-examines the issue of how much of working memory storage is central, or shared across sensory modalities and verbal and nonverbal codes, and how much is peripheral, or specific to a modality or code. In addition to the exploration of many parameters in 9 new dual-task experiments and re-analysis of some prior evidence, the innovations of the present work compared to previous studies of memory for two stimulus sets include (1) use of a principled set of formulas to estimate the number of items in working memory, and (2) a model to dissociate central components, which are allocated to very different stimulus sets depending on the instructions, from peripheral components, which are used for only one kind of material. We consistently find that the central contribution is smaller than was suggested by Saults and Cowan (2007), and that the peripheral contribution is often much larger when the task does not require the binding of features within an object. Previous capacity estimates are consistent with the sum of central plus peripheral components observed here. We consider the implications of the data as constraints on theories of working memory storage and maintenance. PMID:24867488

  18. Supporting capacity sharing in the cloud manufacturing environment based on game theory and fuzzy logic

    NASA Astrophysics Data System (ADS)

    Argoneto, Pierluigi; Renna, Paolo

    2016-02-01

    This paper proposes a Framework for Capacity Sharing in Cloud Manufacturing (FCSCM) able to support the capacity sharing issue among independent firms. The success of geographical distributed plants depends strongly on the use of opportune tools to integrate their resources and demand forecast in order to gather a specific production objective. The framework proposed is based on two different tools: a cooperative game algorithm, based on the Gale-Shapley model, and a fuzzy engine. The capacity allocation policy takes into account the utility functions of the involved firms. It is shown how the capacity allocation policy proposed induces all firms to report truthfully their information about their requirements. A discrete event simulation environment has been developed to test the proposed FCSCM. The numerical results show the drastic reduction of unsatisfied capacity obtained by the model of cooperation implemented in this work.

  19. 16 CFR Appendix H to Part 305 - Cooling Performance and Cost for Central Air Conditioners

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... for Central Air Conditioners Manufacturer's rated cooling capacities (Btu's/hr.) Range of SEER's Low High Single Package Units Central Air Conditioners (Cooling Only): All capacities 10.6 16.5 Heat Pumps (Cooling Function): All capacities 10.6 16.0 Split System Units Central Air Conditioners (Cooling Only...

  20. Peer-to-peer architecture for multi-departmental distributed PACS

    NASA Astrophysics Data System (ADS)

    Rosset, Antoine; Heuberger, Joris; Pysher, Lance; Ratib, Osman

    2006-03-01

    We have elected to explore peer-to-peer technology as an alternative to centralized PACS architecture for the increasing requirements for wide access to images inside and outside a radiology department. The goal being to allow users across the enterprise to access any study anytime without the need for prefetching or routing of images from central archive. Images can be accessed between different workstations and local storage nodes. We implemented "bonjour" a new remote file access technology developed by Apple allowing applications to share data and files remotely with optimized data access and data transfer. Our Open-source image display platform called OsiriX was adapted to allow sharing of local DICOM images through direct access of each local SQL database to be accessible from any other OsiriX workstation over the network. A server version of Osirix Core Data database also allows to access distributed archives servers in the same way. The infrastructure implemented allows fast and efficient access to any image anywhere anytime independently from the actual physical location of the data. It also allows benefiting from the performance of distributed low-cost and high capacity storage servers that can provide efficient caching of PACS data that was found to be 10 to 20 x faster that accessing the same date from the central PACS archive. It is particularly suitable for large hospitals and academic environments where clinical conferences, interdisciplinary discussions and successive sessions of image processing are often part of complex workflow or patient management and decision making.

  1. 16 CFR 305.7 - Determinations of capacity.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... appendix P to 10 CFR part 430, subpart B. (f) Room air conditioners. The capacity shall be the cooling... 430, subpart B. (i) Central air conditioners, cooling. The capacity shall be the cooling capacity in... capacities between 38,000 and 64,999 Btu's per hour. (j) Central air conditioners, heating. The capacity...

  2. Institutional capacity for health systems research in East and Central Africa schools of public health: enhancing capacity to design and implement teaching programs.

    PubMed

    Nangami, Mabel N; Rugema, Lawrence; Tebeje, Bosena; Mukose, Aggrey

    2014-06-02

    The role of health systems research (HSR) in informing and guiding national programs and policies has been increasingly recognized. Yet, many universities in sub-Saharan African countries have relatively limited capacity to teach HSR. Seven schools of public health (SPHs) in East and Central Africa undertook an HSR institutional capacity assessment, which included a review of current HSR teaching programs. This study determines the extent to which SPHs are engaged in teaching HSR-relevant courses and assessing their capacities to effectively design and implement HSR curricula whose graduates are equipped to address HSR needs while helping to strengthen public health policy. This study used a cross-sectional study design employing both quantitative and qualitative approaches. An organizational profile tool was administered to senior staff across the seven SPHs to assess existing teaching programs. A self-assessment tool included nine questions relevant to teaching capacity for HSR curricula. The analysis triangulates the data, with reflections on the responses from within and across the seven SPHs. Proportions and average of values from the Likert scale are compared to determine strengths and weaknesses, while themes relevant to the objectives are identified and clustered to elicit in-depth interpretation. None of the SPHs offer an HSR-specific degree program; however, all seven offer courses in the Master of Public Health (MPH) degree that are relevant to HSR. The general MPH curricula partially embrace principles of competency-based education. Different strengths in curricula design and staff interest in HSR at each SPH were exhibited but a number of common constraints were identified, including out-of-date curricula, face-to-face delivery approaches, inadequate staff competencies, and limited access to materials. Opportunities to align health system priorities to teaching programs include existing networks. Each SPH has key strengths that can be leveraged to design and implement HSR teaching curricula. We propose networking for standardizing HSR curricula competencies, institutionalizing sharing of teaching resources, creating an HSR eLearning platform to expand access, regularly reviewing HSR teaching content to infuse competency-based approaches, and strengthening staff capacity to deliver such curricula.

  3. Institutional capacity for health systems research in East and Central Africa schools of public health: enhancing capacity to design and implement teaching programs

    PubMed Central

    2014-01-01

    Background The role of health systems research (HSR) in informing and guiding national programs and policies has been increasingly recognized. Yet, many universities in sub-Saharan African countries have relatively limited capacity to teach HSR. Seven schools of public health (SPHs) in East and Central Africa undertook an HSR institutional capacity assessment, which included a review of current HSR teaching programs. This study determines the extent to which SPHs are engaged in teaching HSR-relevant courses and assessing their capacities to effectively design and implement HSR curricula whose graduates are equipped to address HSR needs while helping to strengthen public health policy. Methods This study used a cross-sectional study design employing both quantitative and qualitative approaches. An organizational profile tool was administered to senior staff across the seven SPHs to assess existing teaching programs. A self-assessment tool included nine questions relevant to teaching capacity for HSR curricula. The analysis triangulates the data, with reflections on the responses from within and across the seven SPHs. Proportions and average of values from the Likert scale are compared to determine strengths and weaknesses, while themes relevant to the objectives are identified and clustered to elicit in-depth interpretation. Results None of the SPHs offer an HSR-specific degree program; however, all seven offer courses in the Master of Public Health (MPH) degree that are relevant to HSR. The general MPH curricula partially embrace principles of competency-based education. Different strengths in curricula design and staff interest in HSR at each SPH were exhibited but a number of common constraints were identified, including out-of-date curricula, face-to-face delivery approaches, inadequate staff competencies, and limited access to materials. Opportunities to align health system priorities to teaching programs include existing networks. Conclusions Each SPH has key strengths that can be leveraged to design and implement HSR teaching curricula. We propose networking for standardizing HSR curricula competencies, institutionalizing sharing of teaching resources, creating an HSR eLearning platform to expand access, regularly reviewing HSR teaching content to infuse competency-based approaches, and strengthening staff capacity to deliver such curricula. PMID:24888353

  4. An open-source software platform for data management, visualisation, model building and model sharing in water, energy and other resource modelling domains.

    NASA Astrophysics Data System (ADS)

    Knox, S.; Meier, P.; Mohammed, K.; Korteling, B.; Matrosov, E. S.; Hurford, A.; Huskova, I.; Harou, J. J.; Rosenberg, D. E.; Thilmant, A.; Medellin-Azuara, J.; Wicks, J.

    2015-12-01

    Capacity expansion on resource networks is essential to adapting to economic and population growth and pressures such as climate change. Engineered infrastructure systems such as water, energy, or transport networks require sophisticated and bespoke models to refine management and investment strategies. Successful modeling of such complex systems relies on good data management and advanced methods to visualize and share data.Engineered infrastructure systems are often represented as networks of nodes and links with operating rules describing their interactions. Infrastructure system management and planning can be abstracted to simulating or optimizing new operations and extensions of the network. By separating the data storage of abstract networks from manipulation and modeling we have created a system where infrastructure modeling across various domains is facilitated.We introduce Hydra Platform, a Free Open Source Software designed for analysts and modelers to store, manage and share network topology and data. Hydra Platform is a Python library with a web service layer for remote applications, called Apps, to connect. Apps serve various functions including network or results visualization, data export (e.g. into a proprietary format) or model execution. This Client-Server architecture allows users to manipulate and share centrally stored data. XML templates allow a standardised description of the data structure required for storing network data such that it is compatible with specific models.Hydra Platform represents networks in an abstract way and is therefore not bound to a single modeling domain. It is the Apps that create domain-specific functionality. Using Apps researchers from different domains can incorporate different models within the same network enabling cross-disciplinary modeling while minimizing errors and streamlining data sharing. Separating the Python library from the web layer allows developers to natively expand the software or build web-based apps in other languages for remote functionality. Partner CH2M is developing a commercial user-interface for Hydra Platform however custom interfaces and visualization tools can be built. Hydra Platform is available on GitHub while Apps will be shared on a central repository.

  5. Evaluating the use of operational management techniques for capacity improvements on shared-use rail corridors : final report.

    DOT National Transportation Integrated Search

    2016-01-01

    The majority of intercity passenger and commuter rail services in the United States (U.S.) operate on the shared-use corridors with : freight rail services. These types of operations tend to be challenging for efficient capacity utilization and relia...

  6. Shared decision-making as an existential journey: Aiming for restored autonomous capacity.

    PubMed

    Gulbrandsen, Pål; Clayman, Marla L; Beach, Mary Catherine; Han, Paul K; Boss, Emily F; Ofstad, Eirik H; Elwyn, Glyn

    2016-09-01

    We describe the different ways in which illness represents an existential problem, and its implications for shared decision-making. We explore core concepts of shared decision-making in medical encounters (uncertainty, vulnerability, dependency, autonomy, power, trust, responsibility) to interpret and explain existing results and propose a broader understanding of shared-decision making for future studies. Existential aspects of being are physical, social, psychological, and spiritual. Uncertainty and vulnerability caused by illness expose these aspects and may lead to dependency on the provider, which underscores that autonomy is not just an individual status, but also a varying capacity, relational of nature. In shared decision-making, power and trust are important factors that may increase as well as decrease the patient's dependency, particularly as information overload may increase uncertainty. The fundamental uncertainty, state of vulnerability, and lack of power of the ill patient, imbue shared decision-making with a deeper existential significance and call for greater attention to the emotional and relational dimensions of care. Hence, we propose that the aim of shared decision-making should be restoration of the patient's autonomous capacity. In doing shared decision-making, care is needed to encompass existential aspects; informing and exploring preferences is not enough. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Confidence Sharing: An Economic Strategy for Efficient Information Flows in Animal Groups

    PubMed Central

    Korman, Amos; Greenwald, Efrat; Feinerman, Ofer

    2014-01-01

    Social animals may share information to obtain a more complete and accurate picture of their surroundings. However, physical constraints on communication limit the flow of information between interacting individuals in a way that can cause an accumulation of errors and deteriorated collective behaviors. Here, we theoretically study a general model of information sharing within animal groups. We take an algorithmic perspective to identify efficient communication schemes that are, nevertheless, economic in terms of communication, memory and individual internal computation. We present a simple and natural algorithm in which each agent compresses all information it has gathered into a single parameter that represents its confidence in its behavior. Confidence is communicated between agents by means of active signaling. We motivate this model by novel and existing empirical evidences for confidence sharing in animal groups. We rigorously show that this algorithm competes extremely well with the best possible algorithm that operates without any computational constraints. We also show that this algorithm is minimal, in the sense that further reduction in communication may significantly reduce performances. Our proofs rely on the Cramér-Rao bound and on our definition of a Fisher Channel Capacity. We use these concepts to quantify information flows within the group which are then used to obtain lower bounds on collective performance. The abstract nature of our model makes it rigorously solvable and its conclusions highly general. Indeed, our results suggest confidence sharing as a central notion in the context of animal communication. PMID:25275649

  8. Confidence sharing: an economic strategy for efficient information flows in animal groups.

    PubMed

    Korman, Amos; Greenwald, Efrat; Feinerman, Ofer

    2014-10-01

    Social animals may share information to obtain a more complete and accurate picture of their surroundings. However, physical constraints on communication limit the flow of information between interacting individuals in a way that can cause an accumulation of errors and deteriorated collective behaviors. Here, we theoretically study a general model of information sharing within animal groups. We take an algorithmic perspective to identify efficient communication schemes that are, nevertheless, economic in terms of communication, memory and individual internal computation. We present a simple and natural algorithm in which each agent compresses all information it has gathered into a single parameter that represents its confidence in its behavior. Confidence is communicated between agents by means of active signaling. We motivate this model by novel and existing empirical evidences for confidence sharing in animal groups. We rigorously show that this algorithm competes extremely well with the best possible algorithm that operates without any computational constraints. We also show that this algorithm is minimal, in the sense that further reduction in communication may significantly reduce performances. Our proofs rely on the Cramér-Rao bound and on our definition of a Fisher Channel Capacity. We use these concepts to quantify information flows within the group which are then used to obtain lower bounds on collective performance. The abstract nature of our model makes it rigorously solvable and its conclusions highly general. Indeed, our results suggest confidence sharing as a central notion in the context of animal communication.

  9. On-demand high-capacity ride-sharing via dynamic trip-vehicle assignment

    PubMed Central

    Alonso-Mora, Javier; Samaranayake, Samitha; Wallar, Alex; Frazzoli, Emilio; Rus, Daniela

    2017-01-01

    Ride-sharing services are transforming urban mobility by providing timely and convenient transportation to anybody, anywhere, and anytime. These services present enormous potential for positive societal impacts with respect to pollution, energy consumption, congestion, etc. Current mathematical models, however, do not fully address the potential of ride-sharing. Recently, a large-scale study highlighted some of the benefits of car pooling but was limited to static routes with two riders per vehicle (optimally) or three (with heuristics). We present a more general mathematical model for real-time high-capacity ride-sharing that (i) scales to large numbers of passengers and trips and (ii) dynamically generates optimal routes with respect to online demand and vehicle locations. The algorithm starts from a greedy assignment and improves it through a constrained optimization, quickly returning solutions of good quality and converging to the optimal assignment over time. We quantify experimentally the tradeoff between fleet size, capacity, waiting time, travel delay, and operational costs for low- to medium-capacity vehicles, such as taxis and van shuttles. The algorithm is validated with ∼3 million rides extracted from the New York City taxicab public dataset. Our experimental study considers ride-sharing with rider capacity of up to 10 simultaneous passengers per vehicle. The algorithm applies to fleets of autonomous vehicles and also incorporates rebalancing of idling vehicles to areas of high demand. This framework is general and can be used for many real-time multivehicle, multitask assignment problems. PMID:28049820

  10. On-demand high-capacity ride-sharing via dynamic trip-vehicle assignment.

    PubMed

    Alonso-Mora, Javier; Samaranayake, Samitha; Wallar, Alex; Frazzoli, Emilio; Rus, Daniela

    2017-01-17

    Ride-sharing services are transforming urban mobility by providing timely and convenient transportation to anybody, anywhere, and anytime. These services present enormous potential for positive societal impacts with respect to pollution, energy consumption, congestion, etc. Current mathematical models, however, do not fully address the potential of ride-sharing. Recently, a large-scale study highlighted some of the benefits of car pooling but was limited to static routes with two riders per vehicle (optimally) or three (with heuristics). We present a more general mathematical model for real-time high-capacity ride-sharing that (i) scales to large numbers of passengers and trips and (ii) dynamically generates optimal routes with respect to online demand and vehicle locations. The algorithm starts from a greedy assignment and improves it through a constrained optimization, quickly returning solutions of good quality and converging to the optimal assignment over time. We quantify experimentally the tradeoff between fleet size, capacity, waiting time, travel delay, and operational costs for low- to medium-capacity vehicles, such as taxis and van shuttles. The algorithm is validated with ∼3 million rides extracted from the New York City taxicab public dataset. Our experimental study considers ride-sharing with rider capacity of up to 10 simultaneous passengers per vehicle. The algorithm applies to fleets of autonomous vehicles and also incorporates rebalancing of idling vehicles to areas of high demand. This framework is general and can be used for many real-time multivehicle, multitask assignment problems.

  11. Wireless Shared Resources: Sharing Right-Of-Way For Wireless Telecommunications, Guidance On Legal And Institutional Issues

    DOT National Transportation Integrated Search

    1997-06-06

    PUBLIC-PRIVATE PARTNERSHIPS SHARED RESOURCE PROJECTS ARE PUBLIC-PRIVATE ARRANGEMENTS THAT INVOLVE SHARING PUBLIC PROPERTY SUCH AS RIGHTS-OF-WAY AND PRIVATE RESOURCES SUCH AS TELECOMMUNICATIONS CAPACITY AND EXPERTISE. TYPICALLY, PRIVATE TELECOMMUNI...

  12. 16 CFR 305.7 - Determinations of capacity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... determined according to appendix P to 10 CFR part 430, subpart B. (f) Room air conditioners. The capacity... 10 CFR part 430, subpart B. (i) Central air conditioners, cooling. The capacity shall be the cooling... hour for capacities between 38,000 and 64,999 Btu's per hour. (j) Central air conditioners, heating...

  13. Substitute consent to data sharing: a way forward for international dementia research?

    PubMed Central

    Thorogood, Adrian; Deschênes St-Pierre, Constance; Knoppers, Bartha Maria

    2017-01-01

    Abstract A deluge of genetic and health-related data is being generated about patients with dementia. International sharing of these data accelerates dementia research. Seeking consent to data sharing is a challenge for dementia research where patients have lost or risk losing legal capacity. The laws of most countries enable substitute decision makers (SDMs) to consent on behalf of incapable adults to research participation. We compare regulatory frameworks governing capacity, research, and personal data protection across eight countries to determine when SDMs can consent to data sharing. In most countries, an SDM can consent to data sharing in the incapable adult's best interests. Best interests typically include consideration of the individual's previously expressed wishes, values and beliefs; well-being; and inclusion in decision making. Countries differ in how these considerations are balanced. A clear previous consent or refusal to share data typically binds the discretion of an SDM. Though generally permissive, National patchworks of laws and guidelines cause confusion. Clarity on the applicable law and processes to enhance ethical decision making are needed to facilitate substitute consent. Researchers can encourage patients to communicate their research preferences before a loss of capacity, and educate SDMs about their ethical and legal duties. The research community must also continue to promote the importance of data sharing in dementia. PMID:28852560

  14. Minority business bidding for local government contracts: the complexity of availability.

    PubMed

    Bangs, Ralph L; Murrell, Audrey; Constance-Huggins, Monique

    2007-01-01

    While minority-business enterprises (MBEs) have gained some access to local government contracts during the last three decades, these firms continue to receive a small share of local government contract spending relative to the number of available firms. Researchers have suggested two general explanations for the low representation of MBEs in contract awards: (1) lack of qualifications and capacity among MBEs, and (2) public and private discrimination against MBEs in contracting processes. This study on prime contract opportunities in a Northern central city and county with a large minority population finds that low bid rates greatly contribute to the low MBE shares of prime contracts and that bidding is reduced by both local government processes and characteristics of the firms. Some implications of these findings are that local governments need to: (1) monitor MBE shares of prime contract bids by size of contract and use share of bids as one measure of program and organizational effectiveness; (2) identify MBEs that are qualified for prime contracts and encourage and help interested firms to submit competitive bids; and (3) ensure that local government policies and practices do not diminish access to information about prime contract opportunities for qualified and interested minority firms. Another implication is that bidders lists should not be a primary basis for determining MBE availability, since many qualified and interested MBEs do not bid because of perceived barriers in local government.

  15. Help Central: Creating a Help Desk and Knowledge Portal in SharePoint

    ERIC Educational Resources Information Center

    Ennis, Lisa A.; Tims, Randy S.

    2012-01-01

    This article discusses the authors' implementation of Help Central, a site within the Lister Hill Library Collection on the University of Alabama-Birmingham's SharePoint server. Initially, Help Central was designed to address the inadequacies in the library's old, static HTML web-based support system, including haphazard issue reporting by staff…

  16. Community Capacity for Watershed Conservation: A Quantitative Assessment of Indicators and Core Dimensions

    NASA Astrophysics Data System (ADS)

    Brinkman, Elliot; Seekamp, Erin; Davenport, Mae A.; Brehm, Joan M.

    2012-10-01

    Community capacity for watershed management has emerged as an important topic for the conservation of water resources. While much of the literature on community capacity has focused primarily on theory construction, there have been few efforts to quantitatively assess community capacity variables and constructs, particularly for watershed management and conservation. This study seeks to identify predictors of community capacity for watershed conservation in southwestern Illinois. A subwatershed-scale survey of residents from four communities located within the Lower Kaskaskia River watershed of southwestern Illinois was administered to measure three specific capacity variables: community empowerment, shared vision and collective action. Principal component analysis revealed key dimensions of each variable. Specifically, collective action was characterized by items relating to collaborative governance and social networks, community empowerment was characterized by items relating to community competency and a sense of responsibility and shared vision was characterized by items relating to perceptions of environmental threats, issues with development, environmental sense of place and quality of life. From the emerging factors, composite measures were calculated to determine the extent to which each variable contributed to community capacity. A stepwise regression revealed that community empowerment explained most of the variability in the composite measure of community capacity for watershed conservation. This study contributes to the theoretical understanding of community capacity by quantifying the role of collective action, community empowerment and shared vision in community capacity, highlighting the need for multilevel interaction to address watershed issues.

  17. KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy (center) makes a presentation to NASA and other officials about the benefits of locating NASA’s new Shared Services Center in the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy (center) makes a presentation to NASA and other officials about the benefits of locating NASA’s new Shared Services Center in the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  18. Utilization of an interorganizational network analysis to evaluate the development of community capacity among a community-academic partnership.

    PubMed

    Clark, Heather R; Ramirez, Albert; Drake, Kelly N; Beaudoin, Christopher E; Garney, Whitney R; Wendel, Monica L; Outley, Corliss; Burdine, James N; Player, Harold D

    2014-01-01

    Following a community health assessment the Brazos Valley Health Partnership (BVHP) organized to address fragmentation of services and local health needs. This regional partnership employs the fundamental principles of community-based participatory research, fostering an equitable partnership with the aim of building community capacity to address local health issues. This article describes changes in relationships as a result of capacity building efforts in a community-academic partnership. Growth in network structure among organizations is hypothesized to be indicative of less fragmentation of services for residents and increased capacity of the BVHP to collectively address local health issues. Each of the participant organizations responded to a series of questions regarding its relationships with other organizations. Each organization was asked about information sharing, joint planning, resource sharing, and formal agreements with other organizations. The network survey has been administered 3 times between 2004 and 2009. Network density increased for sharing information and jointly planning events. Growth in the complexity of relationships was reported for sharing tangible resources and formal agreements. The average number of ties between organizations as well as the strength of relationships increased. This study provides evidence that the community capacity building efforts within these communities have contributed to beneficial changes in interorganizational relationships. Results from this analysis are useful for understanding how a community partnership's efforts to address access to care can strengthen a community's capacity for future action. Increased collaboration also leads to new assets, resources, and the transfer of knowledge and skills.

  19. Uncover it, students would learn leadership from Team-Based Learning (TBL): The effect of guided reflection and feedback.

    PubMed

    Alizadeh, Maryam; Mirzazadeh, Azim; Parmelee, Dean X; Peyton, Elizabeth; Janani, Leila; Hassanzadeh, Gholamreza; Nedjat, Saharnaz

    2017-04-01

    Little is known about best practices for teaching and learning leadership through Team-Based learning™ (TBL™) with medical students. We hypothesized that guided reflection and feedback would improve shared leadership and shared leadership capacity, and enhance team decision quality in TBL teams. We used the Kolb experiential learning theory as the theoretical framework. The study was conducted at Tehran University of Medical Sciences. Three TBL sessions with 206 students (39 teams) participated in the study. Using a quasi-experimental design, one batch received guided reflection and feedback on their team leadership processes (n = 20 teams) and the other received only TBL (n = 19 teams). Observers measured shared leadership using a checklist. Shared leadership capacity was measured using a questionnaire. Scores on a team application exercise were used to assess quality of team decisions. Evidence did not support our first hypothesis that reflection and feedback enhance shared leadership in TBL teams. Percentages of teams displaying shared leadership did not differ between intervention and control groups in sessions 1 (p = 0.6), 2 (p = 1) or 3 (p = 1). The results did not support the second hypothesis. We found no difference in quality of decision making between the intervention and control groups for sessions 1 (p = 0.77), 2 (p = 0.23), or 3 (p = 0.07). The third hypothesis that the reflection and feedback would have an effect on shared leadership capacity was supported (T = -8.55, p > 0.001 adjusted on baseline; T = -8.55, p > 0.001 adjusted on gender). We found that reflection and feedback improved shared leadership capacity but not shared leadership behaviors or team decision quality. We propose medical educators who apply TBL, should provide guided exercise in reflection and feedback so that students may better understand the benefits of working in teams as preparation for their future roles as leaders and members of health care teams.

  20. Establishing Networks to Lever Investments in Developing Capacity for Agricultural Monitoring: A GEOGLAM Perspective

    NASA Astrophysics Data System (ADS)

    Whitcraft, A. K.; Becker-Reshef, I.

    2016-12-01

    Since 2011, the Group on Earth Observations Global Agricultural Monitoring (GEOGLAM) Initiative has been working to strengthen the international community's capacity to use Earth observation (EO) data to derive timely, accurate, and transparent information on agriculture. A key component of GEOGLAM is the development of individual and institutional capacity for EO-based agricultural monitoring at multiple scales, from national to regional to global, in low-, middle-, and high-income countries. Despite the fact that the need for enhancing capacity is frequently acknowledged, there is little formal or informal literature documenting best practices for developing and implementing comprehensive capacity development strategies around Earth observations knowledge sharing. As a result, many projects and activities develop knowledge-sharing strategies on an ad hoc basis, and may be missing out on levering lessons, techniques, and toolsets already developed. In the past year, GEOGLAM has aimed to spur relationships and collaborations with capacity development initiatives and networks, toward sharing and documenting strategies and tactical experiences in this domain. This presentation will provide some perspective on challenges and opportunities encountered so far, from the GEOGLAM perspective, with the goal of continued dialogue and coordination with other session participants.

  1. A Drosophila In Vivo Injury Model for Studying Neuroregeneration in the Peripheral and Central Nervous System.

    PubMed

    Li, Dan; Li, Feng; Guttipatti, Pavithran; Song, Yuanquan

    2018-05-05

    The regrowth capacity of damaged neurons governs neuroregeneration and functional recovery after nervous system trauma. Over the past few decades, various intrinsic and extrinsic inhibitory factors involved in the restriction of axon regeneration have been identified. However, simply removing these inhibitory cues is insufficient for successful regeneration, indicating the existence of additional regulatory machinery. Drosophila melanogaster, the fruit fly, shares evolutionarily conserved genes and signaling pathways with vertebrates, including humans. Combining the powerful genetic toolbox of flies with two-photon laser axotomy/dendriotomy, we describe here the Drosophila sensory neuron - dendritic arborization (da) neuron injury model as a platform for systematically screening for novel regeneration regulators. Briefly, this paradigm includes a) the preparation of larvae, b) lesion induction to dendrite(s) or axon(s) using a two-photon laser, c) live confocal imaging post-injury and d) data analysis. Our model enables highly reproducible injury of single labeled neurons, axons, and dendrites of well-defined neuronal subtypes, in both the peripheral and central nervous system.

  2. Managing the water-energy-food nexus: Opportunities in Central Asia

    NASA Astrophysics Data System (ADS)

    Jalilov, Shokhrukh-Mirzo; Amer, Saud A.; Ward, Frank A.

    2018-02-01

    This article examines impacts of infrastructure development and climate variability on economic outcomes for the Amu Darya Basin in Central Asia. It aims to identify the most economically productive mix of expanded reservoir storage for economic benefit sharing to occur, in which economic welfare of all riparians is improved. Policies examined include four combinations of storage infrastructure for each of two climate futures. An empirical optimization model is developed and applied to identify opportunities for improving the welfare of Tajikistan, Uzbekistan, Afghanistan, and Turkmenistan. The analysis 1) characterizes politically constrained and economically optimized water-use patterns for these combinations of expanded reservoir storage capacity, 2) describes Pareto-Improving packages of expanded storage capacity that could raise economic welfare for all four riparians, and accounts for impacts for each of two climate scenarios. Results indicate that a combination of targeted water storage infrastructure and efficient water allocation could produce outcomes for which the discounted net present value of benefits are favorable for each riparian. Results identify a framework to provide economic motivation for all riparians to cooperate through development of water storage infrastructure. Our findings illustrate the principle that development of water infrastructure can expand the negotiation space by which all communities can gain economic benefits in the face of limited water supply. Still, despite our optimistic findings, patient and deliberate negotiation will be required to transform potential improvements into actual gains.

  3. Shared learning in general practice--facilitators and barriers.

    PubMed

    van de Mortel, Thea; Silberberg, Peter; Ahern, Christine

    2013-03-01

    Capacity for teaching in general practice clinics is limited. Shared learning sessions are one form of vertically integrated teaching that may ameliorate capacity constraints. This study sought to understand the perceptions of general practitioner supervisors, learners and practice staff of the facilitators of shared learning in general practice clinics. Using a grounded theory approach, semistructured interviews were conducted and analysed to generate a theory about the topic. Thirty-five stakeholders from nine general practices participated. Facilitators of shared learning included enabling factors such as small group facilitation skills, space, administrative support and technological resources; reinforcing factors such as targeted funding, and predisposing factors such as participant attributes. Views from multiple stakeholders suggest that the implementation of shared learning in general practice clinics would be supported by an ecological approach that addresses all these factors.

  4. Advancing the Practice of CRCs: Why Professional Development Matters.

    PubMed

    Behar-Horenstein, Linda S; Prikhidko, Alena; Kolb, H Robert

    2018-01-01

    Clinical research coordinators (CRCs) assume critical responsibilities central to the success of the research team. The complexity of their role requires essential professional qualifications. One barrier to professionalization, however, has been the inconsistent, or absent, competency-based training. This study explored participants' perceptions of training experiences designed to prepare them for the national certification exam. Focus group methodology was used to document their experiences. The findings showed that sustainable mentoring relationships developed, participant confidence levels increased, and anxiety about performance capacity diminished. Cognitive reframing of the work environment and CRC roles was facilitated by training that fostered sharing and social reinforcement of professional and personal identities. Findings from this study suggest that access to meaningful training and quality instruction supports the professionalization of CRCs.

  5. Flow experience in teams: The role of shared leadership.

    PubMed

    Aubé, Caroline; Rousseau, Vincent; Brunelle, Eric

    2018-04-01

    The present study tests a multilevel mediation model concerning the effect of shared leadership on team members' flow experience. Specifically, we investigate the mediating role of teamwork behaviors in the relationships between 2 complementary indicators of shared leadership (i.e., density and centralization) and flow. Based on a multisource approach, we collected data through observation and survey of 111 project teams (521 individuals) made up of university students participating in a project management simulation. The results show that density and centralization have both an additive effect and an interaction effect on teamwork behaviors, such that the relationship between density and teamwork behaviors is stronger when centralization is low. In addition, teamwork behaviors play a mediating role in the relationship between shared leadership and flow. Overall, the findings highlight the importance of promoting team-based shared leadership in organizations to favor the flow experience. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  6. Upstream capacity upgrade in TDM-PON using RSOA based tunable fiber ring laser.

    PubMed

    Yi, Lilin; Li, Zhengxuan; Dong, Yi; Xiao, Shilin; Chen, Jian; Hu, Weisheng

    2012-04-23

    An upstream multi-wavelength shared (UMWS) time division multiplexing passive optical network (TDM-PON) is presented by using a reflective semiconductor amplifier (RSOA) and tunable optical filter (TOF) based directly modulated fiber ring laser as upstream laser source. The stable laser operation is easily achieved no matter what the bandwidth and shape of the TOF is and it can be directly modulated when the RSOA is driven at its saturation region. In this UMWS TDM-PON system, an individual wavelength can be assigned to the user who has a high bandwidth demand by tuning the central wavelength of the TOF in its upgraded optical network unit (ONU), while others maintain their traditional ONU structure and share the bandwidth via time slots, which greatly and dynamically upgrades the upstream capacity. We experimentally demonstrated the bidirectional transmission of downstream data at 10-Gb/s and upstream data at 1.25-Gb/s per wavelength over 25-km single mode fiber (SMF) with almost no power penalty at both ends. A stable performance is observed for the upstream wavelength tuned from 1530 nm to 1595 nm. Moreover, due to the high extinction ratio (ER) of the upstream signal, the burst-mode transmitting is successfully presented and a better time-division multiplexing performance can be obtained by turning off the unused lasers thanks to the rapid formation of the laser in the fiber ring. © 2012 Optical Society of America

  7. 78 FR 45521 - Centralized Capacity Markets in Regional Transmission Organizations and Independent System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    .... This conference is free of charge and open to the public. Commission members may participate in the..., supplement or substitute for typical centralized capacity market design elements in order to meet current and... Capacity Markets in Regional Transmission Organizations and Independent System Operators:Supplemental...

  8. Nonlinear secret image sharing scheme.

    PubMed

    Shin, Sang-Ho; Lee, Gil-Je; Yoo, Kee-Young

    2014-01-01

    Over the past decade, most of secret image sharing schemes have been proposed by using Shamir's technique. It is based on a linear combination polynomial arithmetic. Although Shamir's technique based secret image sharing schemes are efficient and scalable for various environments, there exists a security threat such as Tompa-Woll attack. Renvall and Ding proposed a new secret sharing technique based on nonlinear combination polynomial arithmetic in order to solve this threat. It is hard to apply to the secret image sharing. In this paper, we propose a (t, n)-threshold nonlinear secret image sharing scheme with steganography concept. In order to achieve a suitable and secure secret image sharing scheme, we adapt a modified LSB embedding technique with XOR Boolean algebra operation, define a new variable m, and change a range of prime p in sharing procedure. In order to evaluate efficiency and security of proposed scheme, we use the embedding capacity and PSNR. As a result of it, average value of PSNR and embedding capacity are 44.78 (dB) and 1.74t⌈log2 m⌉ bit-per-pixel (bpp), respectively.

  9. Nonlinear Secret Image Sharing Scheme

    PubMed Central

    Shin, Sang-Ho; Yoo, Kee-Young

    2014-01-01

    Over the past decade, most of secret image sharing schemes have been proposed by using Shamir's technique. It is based on a linear combination polynomial arithmetic. Although Shamir's technique based secret image sharing schemes are efficient and scalable for various environments, there exists a security threat such as Tompa-Woll attack. Renvall and Ding proposed a new secret sharing technique based on nonlinear combination polynomial arithmetic in order to solve this threat. It is hard to apply to the secret image sharing. In this paper, we propose a (t, n)-threshold nonlinear secret image sharing scheme with steganography concept. In order to achieve a suitable and secure secret image sharing scheme, we adapt a modified LSB embedding technique with XOR Boolean algebra operation, define a new variable m, and change a range of prime p in sharing procedure. In order to evaluate efficiency and security of proposed scheme, we use the embedding capacity and PSNR. As a result of it, average value of PSNR and embedding capacity are 44.78 (dB) and 1.74t⌈log2⁡m⌉ bit-per-pixel (bpp), respectively. PMID:25140334

  10. Key factors of clinical research network capacity building.

    PubMed

    Li, Guowei; Wu, Qianyu; Jin, Yanling; Vanniyasingam, Thuva; Thabane, Lehana

    2018-01-01

    In general, clinical research network capacity building refers to programs aimed at enhancing networks of researchers to conduct clinical research. Although in the literature there is a large body of research on how to develop and build capacity in clinical research networks, the conceptualizations and implementations remain controversial and challenging. Moreover, the experiences learnt from the past accomplishments and failures can assist in the future capacity building efforts to be more practical, effective and efficient. In this paper, we aim to provide an overview of capacity building in clinical research network by (1) identifying the key barriers to clinical research network capacity building, (2) providing insights into how to overcome those obstacles, and (3) sharing our experiences in collaborating with national and international partners to build capacity in clinical research networks. In conclusion, we have provided some insight into how to address the key factors of clinical research network capacity building and shared some empirical experiences. A successful capacity building practice requires a joint endeavor to procure sufficient resources and support from the relevant stakeholders, to ensure its efficiency, cost-effectiveness, and sustainability.

  11. Convergent? Minds? Some questions about mental evolution.

    PubMed

    Cartmill, Matt

    2017-06-06

    In investigating convergent minds, we need to be sure that the things we are looking at are both minds and convergent. In determining whether a shared character state represents a convergence between two organisms, we must know the wider distribution and primitive state of that character so that we can map that character and its state transitions onto a phylogenetic tree. When we do this, some apparently primitive shared traits may prove to represent convergent losses of cognitive capacities. To avoid having to talk about the minds of plants and paramecia, we need to go beyond assessments of behaviourally defined cognition to ask questions about mind in the primary sense of the word, defined by the presence of mental events and consciousness. These phenomena depend upon the possession of brains of adequate size and centralized ontogeny and organization. They are probably limited to vertebrates. Recent discoveries suggest that consciousness is adaptively valuable as a late error-detection mechanism in the initiation of action, and point to experimental techniques for assessing its presence or absence in non-human mammals.

  12. Carotid flow pulsatility is higher in women with greater decrement in gait speed during multi-tasking.

    PubMed

    Gonzales, Joaquin U; James, C Roger; Yang, Hyung Suk; Jensen, Daniel; Atkins, Lee; Al-Khalil, Kareem; O'Boyle, Michael

    2017-05-01

    Central arterial hemodynamics is associated with cognitive impairment. Reductions in gait speed during walking while performing concurrent tasks known as dual-tasking (DT) or multi-tasking (MT) is thought to reflect the cognitive cost that exceeds neural capacity to share resources. We hypothesized that central vascular function would associate with decrements in gait speed during DT or MT. Gait speed was measured using a motion capture system in 56 women (30-80y) without mild-cognitive impairment. Dual-tasking was considered walking at a fast-pace while balancing a tray. Multi-tasking was the DT condition plus subtracting by serial 7's. Applanation tonometry was used for measurement of aortic stiffness and central pulse pressure. Doppler-ultrasound was used to measure blood flow velocity and β-stiffness index in the common carotid artery. The percent change in gait speed was larger for MT than DT (14.1±11.2 vs. 8.7±9.6%, p <0.01). Tertiles were formed based on the percent change in gait speed for each condition. No vascular parameters differed across tertiles for DT. In contrast, carotid flow pulsatility (1.85±0.43 vs. 1.47±0.42, p=0.02) and resistance (0.75±0.07 vs. 0.68±0.07, p=0.01) indices were higher in women with more decrement (third tertile) as compared to women with less decrement (first tertile) in gait speed during MT after adjusting for age, gait speed, and task error. Carotid pulse pressure and β-stiffness did not contribute to these tertile differences. Elevated carotid flow pulsatility and resistance are characteristics found in healthy women that show lower cognitive capacity to walk and perform multiple concurrent tasks. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Combating Terrorism: Additional Steps Needed to Enhance Foreign Partners’ Capacity to Prevent Terrorist Travel

    DTIC Science & Technology

    2011-06-01

    identified enhancing the capacity of partner nations as one of two pillars supporting that strategy. The attempted attack on a Detroit-bound airliner on...not have reciprocal relationships to share such information or other travel-related information, such as airline passenger lists, with other...Bureau of European and Eurasian Affairs • Negotiations to share Passenger Name Records data to prescreen airline passengers against terrorist

  14. On Channel Sharing in Discrete-Time, Multi-Access Broadcast Communications,

    DTIC Science & Technology

    1980-09-01

    towards a physical intepretation . of the solutions. 1.4.3 THE PROBLEM OF CAPACITY Our discussion of capacity has two objectives. First, to explore...8021 (DARPA). Yemnii, Y., "On Channel Sharing in Discrete-Time, Multi-Access Broadcast Communication," Sep- tember 1980, UCLA-ENG-8061. (DARPA). 280 FILMED 9-83 DTIC 𔃾’W 9111 ’K4VFClMlP-- Om mFoca 1,00,

  15. Study on evaluation of environmental carrying capacity of pig breeding in Central China

    NASA Astrophysics Data System (ADS)

    Leng, Bi-Bin; Liu, Wei; Ji, Xue-Qiang; Zhang, Qi-Zhen

    2017-08-01

    China’s central six provinces are located in the hinterland of the mainland of China and play an increasingly important role in the process of China’s economic and social development. This paper uses the 2016 statistical yearbook data to synthesize the environmental carrying capacity of six provinces in central China Evaluation. The results show that Shanxi Province has the highest environmental pollution carrying index, followed by Jiangxi Province, Anhui Province, Hunan Province and Hubei Province. Henan Province is with the lowest index, which shows that the carrying capacity of pig breeding in Shanxi outpaces the other provinces. And Henan Province owns the weakest carrying capacity.

  16. KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy makes a presentation to NASA and other officials about the benefits of locating NASA’s new Shared Services Center in the Central Florida Research Park, near Orlando. At the far left is Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy makes a presentation to NASA and other officials about the benefits of locating NASA’s new Shared Services Center in the Central Florida Research Park, near Orlando. At the far left is Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  17. Number As a Primary Perceptual Attribute: A Review.

    PubMed

    Anobile, Giovanni; Cicchini, Guido Marco; Burr, David C

    2016-01-01

    Although humans are the only species to possess language-driven abstract mathematical capacities, we share with many other animals a nonverbal capacity for estimating quantities or numerosity. For some time, researchers have clearly differentiated between small numbers of items--less than about four--referred to as the subitizing range, and larger numbers, where counting or estimation is required. In this review, we examine more recent evidence suggesting a further division, between sets of items greater than the subitizing range, but sparse enough to be individuated as single items; and densely packed stimuli, where they crowd each other into what is better considered as a texture. These two different regimes are psychophysically discriminable in that they follow distinct psychophysical laws and show different dependencies on eccentricity and on luminance levels. But provided the elements are not too crowded (less than about two items per square degree in central vision, less in the periphery), there is little evidence that estimation of numerosity depends on mechanisms responsive to texture. The distinction is important, as the ability to discriminate numerosity, but not texture, correlates with formal maths skills. © The Author(s) 2015.

  18. Function Allocation between Automation and Human Pilot for Airborne Separation Assurance

    NASA Technical Reports Server (NTRS)

    Idris, Husni; Enea, Gabriele; Lewis, TImothy A.

    2016-01-01

    Maintaining safe separation between aircraft is a key determinant of the airspace capacity to handle air transportation. With the advent of satellite-based surveillance, aircraft equipped with the needed technologies are now capable of maintaining awareness of their location in the airspace and sharing it with their surrounding traffic. As a result, concepts and cockpit automation are emerging to enable delegating the responsibility of maintaining safe separation from traffic to the pilot; thus increasing the airspace capacity by alleviating the limitation of the current non-scalable centralized ground-based system. In this paper, an analysis of allocating separation assurance functions to the human pilot and cockpit automation is presented to support the design of these concepts and technologies. A task analysis was conducted with the help of Petri nets to identify the main separation assurance functions and their interactions. Each function was characterized by three behavior levels that may be needed to perform the task: skill, rule and knowledge based levels. Then recommendations are made for allocating each function to an automation scale based on their behavior level characterization and with the help of Subject matter experts.

  19. 78 FR 37537 - Centralized Capacity Markets in Regional Transmission Organizations and Independent System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-21

    ... existing centralized capacity markets (e.g., resource adequacy, long-term price signals, fixed-cost[email protected] . Sarah McKinley (Logistical Information), Office of External Affairs, Federal Energy...

  20. Identifying organizational capacities and incentives for clinical data-sharing: the case of a regional perinatal information system.

    PubMed

    Korst, Lisa M; Signer, Jordana M K; Aydin, Carolyn E; Fink, Arlene

    2008-01-01

    The development of regional data-sharing among healthcare organizations is viewed as an important step in the development of health information technology (HIT), but little is known about this complex task. This is a case study of a regional perinatal data system that involved four hospitals, together responsible for over 10,000 births annually. Using standard qualitative methods, we chronicled project milestones, and identified 31 "critical incidents" that delayed or prevented their achievement. We then used these critical incidents to articulate six organizational capacity domains associated with the achievement of project milestones, and a seventh domain consisting of organizational incentives. Finally, we analyzed the relationship of milestone achievement to the presence of these capacities and incentives. This data center case suggests four requirements for sharing data across organizations: 1) a readiness assessment; 2) a perceived mandate; 3) a formal governance structure; and 4) a third party IT component.

  1. Phases of "pre-engagement" capacity building: discovery, exploration, and trial alliance.

    PubMed

    Campbell-Voytal, Kimberly

    2010-01-01

    Academic prevention researchers who engage limited-resource communities may find that organizational or community capacity for prevention is low. Community organizations, neighborhoods, and academic partners may lack shared issue awareness, mutual interests, and interactive skills necessary for collaborative intervention. Existing capacity building models either ignore a 'pre-engagement' phase or acknowledge it without offering strategic detail. An exploratory or developmental phase before active engagement can be achieved through co-located work in a community setting. The construct, "ecology of practice," provides conceptual background for examining how "shared work" introduces and prepares partners for future collaboration consistent with community-based participatory research (CBPR) principles. This paper presents two case studies where pre-engagement capacity building involved partners who were initially unaware, disinterested, or unable to engage in preventive interventions. These cases illustrate how mutual participation in shared "ecologies of practice" enabled an exchange of cultural knowledge, skill, and language that laid the groundwork for future preventive intervention. A trajectory of developmental work in each case occurred over 5 years. Historical timelines, interviews, and personal communications between community and academic leaders were reviewed and common themes identified. A model of "pre-capacity building" emerged. Capacity-building models that detail strategies for developing equitable engagement in under-resourced settings will more effectively move best practices into vulnerable communities. Preventive interventions must be translated equitably if health disparities are to be reduced.

  2. Tourism Skills Delivery: Sharing Tourism Knowledge Online

    ERIC Educational Resources Information Center

    Braun, Patrice; Hollick, Mary

    2006-01-01

    Purpose: The purpose of this paper is to share the authors' initial insights into tourism industry capacity building via flexibly delivered online skilling and knowledge sharing. Design/methodology/approach: An online research survey approach was employed, involving a sample of 64 micro tourism operators. Findings: The paper finds that the major…

  3. Physician Willingness and Resources to Serve More Medicaid Patients: Perspectives from Primary Care Physicians

    PubMed Central

    Sommers, Anna S.; Paradise, Julia; Miller, Carolyn

    2011-01-01

    Objective Sixteen million people will gain Medicaid under health reform. This study compares primary care physicians (PCPs) on reported acceptance of new Medicaid patients and practice characteristics. Data and Methods Sample of 1,460 PCPs in outpatient settings was drawn from a 2008 nationally representative survey of physicians. PCPs were classified into four categories based on distribution of practice revenue from Medicaid and Medicare and acceptance of new Medicaid patients. Fifteen in-depth telephone interviews supplemented analysis. Findings Most high- and moderate-share Medicaid PCPs report accepting “all” or “most” new Medicaid patients. High-share Medicaid PCPs were more likely than others to work in hospital-based practices (20%) and health centers (18%). About 30% of high- and moderate-share Medicaid PCPs worked in practices with a hospital ownership interest. Health IT use was similar between these two groups and high-share Medicare PCPs, but more high- and moderate-share Medicaid PCPs provided interpreters and non-physician staff for patient education. Over 40% of high- and moderate-share Medicaid PCPs reported inadequate patient time as a major problem. Low- and no-share Medicaid PCPs practiced in higher-income areas than high-share Medicaid PCPs. In interviews, difficulty arranging specialist care, reimbursement, and administrative hassles emerged as reasons for limiting Medicaid patients. Policy Implications PCPs already serving Medicaid are positioned to expand capacity but also face constraints. Targeted efforts to increase their capacity could help. Acceptance of new Medicaid patients under health reform will hinge on multiple factors, not payment alone. Trends toward hospital ownership could increase practices' capacity and willingness to serve Medicaid. PMID:22340772

  4. Clinical Trial Data as Public Goods: Fair Trade and the Virtual Knowledge Bank as a Solution to the Free Rider Problem - A Framework for the Promotion of Innovation by Facilitation of Clinical Trial Data Sharing among Biopharmaceutical Companies in the Era of Omics and Big Data.

    PubMed

    Evangelatos, Nikolaos; Reumann, Matthias; Lehrach, Hans; Brand, Angela

    2016-01-01

    Knowledge in the era of Omics and Big Data has been increasingly conceptualized as a public good. Sharing of de-identified patient data has been advocated as a means to increase confidence and public trust in the results of clinical trials. On the other hand, research has shown that the current research and development model of the biopharmaceutical industry has reached its innovation capacity. In response to that, the biopharmaceutical industry has adopted open innovation practices, with sharing of clinical trial data being among the most interesting ones. However, due to the free rider problem, clinical trial data sharing among biopharmaceutical companies could undermine their innovativeness. Based on the theory of public goods, we have developed a commons arrangement and devised a model, which enables secure and fair clinical trial data sharing over a Virtual Knowledge Bank based on a web platform. Our model uses data as a virtual currency and treats knowledge as a club good. Fair sharing of clinical trial data over the Virtual Knowledge Bank has positive effects on the innovation capacity of the biopharmaceutical industry without compromising the intellectual rights, proprietary interests and competitiveness of the latter. The Virtual Knowledge Bank is a sustainable and self-expanding model for secure and fair clinical trial data sharing that allows for sharing of clinical trial data, while at the same time it increases the innovation capacity of the biopharmaceutical industry. © 2016 S. Karger AG, Basel.

  5. How much electrical energy storage do we need? A synthesis for the U.S., Europe, and Germany

    DOE PAGES

    Cebulla, Felix; Haas, Jannik; Eichman, Josh; ...

    2018-02-03

    Electrical energy storage (EES) is a promising flexibility source for prospective low-carbon energy systems. In the last couple of years, many studies for EES capacity planning have been produced. However, these resulted in a very broad range of power and energy capacity requirements for storage, making it difficult for policymakers to identify clear storage planning recommendations. Therefore, we studied 17 recent storage expansion studies pertinent to the U.S., Europe, and Germany. We then systemized the storage requirement per variable renewable energy (VRE) share and generation technology. Our synthesis reveals that with increasing VRE shares, the EES power capacity increases linearly;more » and the energy capacity, exponentially. Further, by analyzing the outliers, the EES energy requirements can be at least halved. It becomes clear that grids dominated by photovoltaic energy call for more EES, while large shares of wind rely more on transmission capacity. Taking into account the energy mix clarifies - to a large degree - the apparent conflict of the storage requirements between the existing studies. Finally, there might exist a negative bias towards storage because transmission costs are frequently optimistic (by neglecting execution delays and social opposition) and storage can cope with uncertainties, but these issues are rarely acknowledged in the planning process.« less

  6. How much electrical energy storage do we need? A synthesis for the U.S., Europe, and Germany

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cebulla, Felix; Haas, Jannik; Eichman, Josh

    Electrical energy storage (EES) is a promising flexibility source for prospective low-carbon energy systems. In the last couple of years, many studies for EES capacity planning have been produced. However, these resulted in a very broad range of power and energy capacity requirements for storage, making it difficult for policymakers to identify clear storage planning recommendations. Therefore, we studied 17 recent storage expansion studies pertinent to the U.S., Europe, and Germany. We then systemized the storage requirement per variable renewable energy (VRE) share and generation technology. Our synthesis reveals that with increasing VRE shares, the EES power capacity increases linearly;more » and the energy capacity, exponentially. Further, by analyzing the outliers, the EES energy requirements can be at least halved. It becomes clear that grids dominated by photovoltaic energy call for more EES, while large shares of wind rely more on transmission capacity. Taking into account the energy mix clarifies - to a large degree - the apparent conflict of the storage requirements between the existing studies. Finally, there might exist a negative bias towards storage because transmission costs are frequently optimistic (by neglecting execution delays and social opposition) and storage can cope with uncertainties, but these issues are rarely acknowledged in the planning process.« less

  7. Top 10 research priorities relating to stroke nursing: a rigorous approach to establish a national nurse-led research agenda.

    PubMed

    Rowat, Anne; Pollock, Alex; St George, Bridget; Cowey, Eileen; Booth, Joanne; Lawrence, Maggie

    2016-11-01

    To determine the top 10 research priorities specific to stroke nursing. It is important that stroke nurses build their research capability and capacity. This project built on a previous James Lind Alliance prioritization project, which established the shared stroke research priorities of stroke survivors, carers and health professionals. Research priority setting project using James Lind Alliance methods; a survey for interim prioritization and a consensus meeting for final priority setting. Between September - November 2014, stroke nurses were invited to select their top 10 priorities from a previously established list of 226 unique unanswered questions. These data were used to generate a list of shared research priorities (interim priority setting stage). A purposefully selected group of stroke nurses attended a final consensus meeting (April 2015) to determine the top 10 research priorities. During the interim prioritization stage, 97 stroke nurses identified 28 shared priority treatment uncertainties. At the final consensus meeting, 27 stroke nurses reached agreement on the top 10 stroke nursing research priorities. Five of the top 10 questions relate to stroke-specific impairments and five relate to rehabilitation and long-term consequences of stroke. The research agenda for stroke nursing has now been clearly defined, facilitating nurses to undertake research, which is of importance to stroke survivors and carers and central to supporting optimal recovery and quality of life after stroke. © 2016 John Wiley & Sons Ltd.

  8. Exploring the Cognitive Foundations of the Shared Attention Mechanism: Evidence for a Relationship between Self-Categorization and Shared Attention across the Autism Spectrum

    ERIC Educational Resources Information Center

    Skorich, Daniel P.; Gash, Tahlia B.; Stalker, Katie L.; Zheng, Lidan; Haslam, S. Alexander

    2017-01-01

    The social difficulties of autism spectrum disorder (ASD) are typically explained as a disruption in the Shared Attention Mechanism (SAM) sub-component of the theory of mind (ToM) system. In the current paper, we explore the hypothesis that SAM's capacity to construct the self-other-object relations necessary for shared-attention arises from a…

  9. EEG measures reveal dual-task interference in postural performance in young adults

    PubMed Central

    Woollacott, Marjorie

    2014-01-01

    The study used a dual-task (DT) postural paradigm (two tasks performed at once) that included electroencephalography (EEG) to examine cortical interference when a visual working memory (VWM) task was paired with a postural task. The change detection task was used, as it requires storage of information without updating or manipulation and predicts VWM capacity. Ground reaction forces (GRFs) (horizontal and vertical), EMG, and EEG elements, time locked to support surface perturbations, were used to infer the active neural processes underlying the automatic control of balance in 14 young adults. A significant reduction was seen between single task (ST) and DT conditions in VWM capacity (F(1,13) = 6.175, p < 0.05, r = 0.6) and event-related potential (ERP) N1 component amplitude over the L motor (p < 0.001) and R sensory (p < 0.05) cortical areas. In addition, a significant increase in the COP trajectory peak (pkcopx) was seen in the DT versus ST condition. Modulation of VWM capacity as well as ERP amplitude and pkcopx in DT conditions provided evidence of an interference pattern, suggesting that the two modalities shared a similar set of attentional resources. The results provide direct evidence of the competition for central processing attentional resources between the two modalities, through the reduction in amplitude of the ERP evoked by the postural perturbation. PMID:25273924

  10. Contingent capture of visual-spatial attention depends on capacity-limited central mechanisms: evidence from human electrophysiology and the psychological refractory period.

    PubMed

    Brisson, Benoit; Leblanc, Emilie; Jolicoeur, Pierre

    2009-02-01

    It has recently been demonstrated that a lateralized distractor that matches the individual's top-down control settings elicits an N2pc wave, an electrophysiological index of the focus of visual-spatial attention, indicating that contingent capture has a visual-spatial locus. Here, we investigated whether contingent capture required capacity-limited central resources by incorporating a contingent capture task as the second task of a psychological refractory period (PRP) dual-task paradigm. The N2pc was used to monitor where observers were attending while they performed concurrent central processing known to cause the PRP effect. The N2pc elicited by the lateralized distractor that matched the top-down control settings was attenuated in high concurrent central load conditions, indicating that although involuntary, the deployment of visual-spatial attention occurring during contingent capture depends on capacity-limited central resources.

  11. The Contribution of Working Memory to Fluid Reasoning: Capacity, Control, or Both?

    ERIC Educational Resources Information Center

    Chuderski, Adam; Necka, Edward

    2012-01-01

    Fluid reasoning shares a large part of its variance with working memory capacity (WMC). The literature on working memory (WM) suggests that the capacity of the focus of attention responsible for simultaneous maintenance and integration of information within WM, as well as the effectiveness of executive control exerted over WM, determines…

  12. 78 FR 6391 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing and Immediate Effectiveness...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... shares other than 100.\\8\\ Moreover, the concept of listing and trading parallel options products of... system capacity, the Exchange has analyzed its capacity and represents that it and the Options Price Reporting Authority (``OPRA'') have the necessary systems capacity to handle the potential additional...

  13. Working memory capacity and visual-verbal cognitive load modulate auditory-sensory gating in the brainstem: toward a unified view of attention.

    PubMed

    Sörqvist, Patrik; Stenfelt, Stefan; Rönnberg, Jerker

    2012-11-01

    Two fundamental research questions have driven attention research in the past: One concerns whether selection of relevant information among competing, irrelevant, information takes place at an early or at a late processing stage; the other concerns whether the capacity of attention is limited by a central, domain-general pool of resources or by independent, modality-specific pools. In this article, we contribute to these debates by showing that the auditory-evoked brainstem response (an early stage of auditory processing) to task-irrelevant sound decreases as a function of central working memory load (manipulated with a visual-verbal version of the n-back task). Furthermore, individual differences in central/domain-general working memory capacity modulated the magnitude of the auditory-evoked brainstem response, but only in the high working memory load condition. The results support a unified view of attention whereby the capacity of a late/central mechanism (working memory) modulates early precortical sensory processing.

  14. Simulation modelling of central order processing system under resource sharing strategy in demand-driven garment supply chains

    NASA Astrophysics Data System (ADS)

    Ma, K.; Thomassey, S.; Zeng, X.

    2017-10-01

    In this paper we proposed a central order processing system under resource sharing strategy for demand-driven garment supply chains to increase supply chain performances. We examined this system by using simulation technology. Simulation results showed that significant improvement in various performance indicators was obtained in new collaborative model with proposed system.

  15. 78 FR 65632 - Centralized Capacity Markets in Regional Transmission Organizations and Independent System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... capacity product, as under current market designs, are there certain fundamental performance standards that... necessary for capacity investment? PJM offers LSEs the alternative to opt out of its capacity auction by... transmission may substitute for capacity resources. How can investment in capacity and transmission planning be...

  16. 78 FR 59924 - Centralized Capacity Markets in Regional Transmission Organizations and Independent System...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... does the changing resource mix (i.e., increased reliance on natural gas-fired generation, increasing... resource planning policies, emerging technologies and fuels such as shale gas, price responsive demand and... design tools could prospectively augment, supplement or substitute for typical centralized capacity...

  17. KSC-04PD-0253

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. KSC Director Jim Kennedy (center) makes a presentation to NASA and other officials about the benefits of locating NASAs new Shared Services Center in the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  18. The benefits of convergence.

    PubMed

    Chang, Gee-Kung; Cheng, Lin

    2016-03-06

    A multi-tier radio access network (RAN) combining the strength of fibre-optic and radio access technologies employing adaptive microwave photonics interfaces and radio-over-fibre (RoF) techniques is envisioned for future heterogeneous wireless communications. All-band radio spectrum from 0.1 to 100 GHz will be used to deliver wireless services with high capacity, high link speed and low latency. The multi-tier RAN will improve the cell-edge performance in an integrated heterogeneous environment enabled by fibre-wireless integration and networking for mobile fronthaul/backhaul, resource sharing and all-layer centralization of multiple standards with different frequency bands and modulation formats. In essence, this is a 'no-more-cells' architecture in which carrier aggregation among multiple frequency bands can be easily achieved with seamless handover between cells. In this way, current and future mobile network standards such as 4G and 5G can coexist with optimized and continuous cell coverage using multi-tier RoF regardless of the underlying network topology or protocol. In terms of users' experience, the future-proof approach achieves the goals of system capacity, link speed, latency and continuous heterogeneous cell coverage while overcoming the bandwidth crunch in next-generation communication networks. © 2016 The Author(s).

  19. Corporate Social Responsibility: A Real Options Approach to the Challenge of Financial Sustainability

    PubMed Central

    2015-01-01

    Background In contemporary complex societies, social values like ethics, corporate social responsibility, and being respectful with the environment, among others, are becoming social requirements. Corporations are expected to fulfill them and, according to empirical evidence, an overwhelming majority aspires to good social valuation. At the same time, the maximization of market share value in the long run continues to be the central corporate goal. Making environmental and social expenses compatible with value creation is a central challenge for corporations since it implies the financial sustainability of Corporate Social Responsibility (CSR). Methods and Results The value creation capacity of CSR projects, mainly through innovation, is widely acknowledged in economic literature and corporate practice. This fact arouses the need of having a quantitative framework capable of summarizing the value creation capacity of the variables involved in CSR projects. With this aim we build up a sensitivity analysis of real option ratios that studies and quantifies the value creation capacity of CSR projects connected with innovation. Ratio analysis has the advantage of being scale independent. Hence, it furnishes a homogeneous framework to express the interaction of value creation variables and, thus, supports strategic thinking quantitatively. Often, CSR expenses can be regarded as preliminary projects that create the opportunity to undertake a full future project. For them, we obtain the minimum expectations scenario that makes financially sustainable a preliminary project that can be interpreted as a call option. We propose a classification of CSR projects from the decision analysis perspective following a two-fold approach: Their relationship with value creation and their links with existing corporate activities. This classification of CSR projects aims at contributing to choose the best capital budgeting method to study the financial sustainability of the project and identifying those CSR projects that fulfill the required features to be studied from the real options perspective. PMID:25938410

  20. Corporate social responsibility: a real options approach to the challenge of financial sustainability.

    PubMed

    Bosch-Badia, Maria-Teresa; Montllor-Serrats, Joan; Tarrazon-Rodon, Maria-Antonia

    2015-01-01

    In contemporary complex societies, social values like ethics, corporate social responsibility, and being respectful with the environment, among others, are becoming social requirements. Corporations are expected to fulfill them and, according to empirical evidence, an overwhelming majority aspires to good social valuation. At the same time, the maximization of market share value in the long run continues to be the central corporate goal. Making environmental and social expenses compatible with value creation is a central challenge for corporations since it implies the financial sustainability of Corporate Social Responsibility (CSR). The value creation capacity of CSR projects, mainly through innovation, is widely acknowledged in economic literature and corporate practice. This fact arouses the need of having a quantitative framework capable of summarizing the value creation capacity of the variables involved in CSR projects. With this aim we build up a sensitivity analysis of real option ratios that studies and quantifies the value creation capacity of CSR projects connected with innovation. Ratio analysis has the advantage of being scale independent. Hence, it furnishes a homogeneous framework to express the interaction of value creation variables and, thus, supports strategic thinking quantitatively. Often, CSR expenses can be regarded as preliminary projects that create the opportunity to undertake a full future project. For them, we obtain the minimum expectations scenario that makes financially sustainable a preliminary project that can be interpreted as a call option. We propose a classification of CSR projects from the decision analysis perspective following a two-fold approach: Their relationship with value creation and their links with existing corporate activities. This classification of CSR projects aims at contributing to choose the best capital budgeting method to study the financial sustainability of the project and identifying those CSR projects that fulfill the required features to be studied from the real options perspective.

  1. The economics of time shared computing: Congestion, user costs and capacity

    NASA Technical Reports Server (NTRS)

    Agnew, C. E.

    1982-01-01

    Time shared systems permit the fixed costs of computing resources to be spread over large numbers of users. However, bottleneck results in the theory of closed queueing networks can be used to show that this economy of scale will be offset by the increased congestion that results as more users are added to the system. If one considers the total costs, including the congestion cost, there is an optimal number of users for a system which equals the saturation value usually used to define system capacity.

  2. Share and Succeed: The Development of Knowledge Sharing and Brokerage in Data Teams' Network Structures

    ERIC Educational Resources Information Center

    Hubers, Mireille D.; Moolenaar, Nienke M.; Schildkamp, Kim; Daly, Alan J.; Handelzalts, Adam; Pieters, Jules M.

    2018-01-01

    The data team intervention was designed to support Dutch secondary schools in using data while developing a solution to an educational problem. A data team can build school-wide capacity for data use through knowledge sharing among data team members, and knowledge brokerage between the team and other colleagues. The goal of this mixed-methods…

  3. The study of environmental carrying capacity for sustainable tourism in Telaga Warna Telaga Pengilon Nature Park, Dieng Plateu, Central Java

    NASA Astrophysics Data System (ADS)

    Melat Aryasa, Alexander; Nur Bambang, Azis; Muhammad, Fuad

    2017-06-01

    The increasing in quantity of the tourists visiting Telaga Warna Telaga Pengilon Nature Park, Dieng Plateau, Central Java, can cause a potential threat toward the conservation sustainability of the tourist attraction and the surrounding area. The utilization of conservation area for tourist attraction has to be carried out based on the principal of Environmental Carrying Capacity so that it will not affect the ecosystem. This study aims to determine the value of Telaga Warna Telaga Pengilon Nature Park environmental carrying capacity as a conservation area used for tourism activities. The environmental carrying capacities calculated in this study were physical carrying capacity, real carrying capacity, and effective carrying capacity. Results of this research show that the physical carrying capacity of The Telaga Warna Telaga Pengilon Nature Park was 31,302 visitors, the real capacity was 869 visitors/day and the effective carrying capacity was 579 visitors/day. Thus, the sustainable tourism development strategy is needed to manage the everlasting natural resources.

  4. Organizational capacity for chronic disease prevention: a survey of Canadian public health organizations.

    PubMed

    Hanusaik, Nancy; O'Loughlin, Jennifer L; Kishchuk, Natalie; Paradis, Gilles; Cameron, Roy

    2010-04-01

    There are no national data on levels of organizational capacity within the Canadian public health system to reduce the burden of chronic disease. Cross-sectional data were collected in a national survey (October 2004 to April 2005) of all 216 national, provincial and regional-level organizations engaged in chronic disease prevention through primary prevention or healthy lifestyle promotion. Levels of organizational capacity (defined as skills and resources to implement chronic disease prevention programmes), potential determinants of organizational capacity and involvement in chronic disease prevention programming were compared in western, central and eastern Canada and across three types of organizations (formal public health organizations, non-governmental organizations and grouped organizations). Forty percent of organizations were located in Central Canada. Approximately 50% were formal public health organizations. Levels of skill and involvement were highest for activities that addressed tobacco control and healthy eating; lowest for stress management, social determinants of health and programme evaluation. The few notable differences in skill levels by provincial grouping favoured Central Canada. Resource adequacy was rated low across the country; but was lowest in eastern Canada and among formal public health organizations. Determinants of organizational capacity (organizational supports and partnerships) were highest in central Canada and among grouped organizations. These data provide an evidence base to identify strengths and gaps in organizational capacity and involvement in chronic disease prevention programming in the organizations that comprise the Canadian public health system.

  5. Motivation enhances visual working memory capacity through the modulation of central cognitive processes.

    PubMed

    Sanada, Motoyuki; Ikeda, Koki; Kimura, Kenta; Hasegawa, Toshikazu

    2013-09-01

    Motivation is well known to enhance working memory (WM) capacity, but the mechanism underlying this effect remains unclear. The WM process can be divided into encoding, maintenance, and retrieval, and in a change detection visual WM paradigm, the encoding and retrieval processes can be subdivided into perceptual and central processing. To clarify which of these segments are most influenced by motivation, we measured ERPs in a change detection task with differential monetary rewards. The results showed that the enhancement of WM capacity under high motivation was accompanied by modulations of late central components but not those reflecting attentional control on perceptual inputs across all stages of WM. We conclude that the "state-dependent" shift of motivation impacted the central, rather than the perceptual functions in order to achieve better behavioral performances. Copyright © 2013 Society for Psychophysiological Research.

  6. The Developmental Influence of Primary Memory Capacity on Working Memory and Academic Achievement

    PubMed Central

    2015-01-01

    In this study, we investigate the development of primary memory capacity among children. Children between the ages of 5 and 8 completed 3 novel tasks (split span, interleaved lists, and a modified free-recall task) that measured primary memory by estimating the number of items in the focus of attention that could be spontaneously recalled in serial order. These tasks were calibrated against traditional measures of simple and complex span. Clear age-related changes in these primary memory estimates were observed. There were marked individual differences in primary memory capacity, but each novel measure was predictive of simple span performance. Among older children, each measure shared variance with reading and mathematics performance, whereas for younger children, the interleaved lists task was the strongest single predictor of academic ability. We argue that these novel tasks have considerable potential for the measurement of primary memory capacity and provide new, complementary ways of measuring the transient memory processes that predict academic performance. The interleaved lists task also shared features with interference control tasks, and our findings suggest that young children have a particular difficulty in resisting distraction and that variance in the ability to resist distraction is also shared with measures of educational attainment. PMID:26075630

  7. The developmental influence of primary memory capacity on working memory and academic achievement.

    PubMed

    Hall, Debbora; Jarrold, Christopher; Towse, John N; Zarandi, Amy L

    2015-08-01

    In this study, we investigate the development of primary memory capacity among children. Children between the ages of 5 and 8 completed 3 novel tasks (split span, interleaved lists, and a modified free-recall task) that measured primary memory by estimating the number of items in the focus of attention that could be spontaneously recalled in serial order. These tasks were calibrated against traditional measures of simple and complex span. Clear age-related changes in these primary memory estimates were observed. There were marked individual differences in primary memory capacity, but each novel measure was predictive of simple span performance. Among older children, each measure shared variance with reading and mathematics performance, whereas for younger children, the interleaved lists task was the strongest single predictor of academic ability. We argue that these novel tasks have considerable potential for the measurement of primary memory capacity and provide new, complementary ways of measuring the transient memory processes that predict academic performance. The interleaved lists task also shared features with interference control tasks, and our findings suggest that young children have a particular difficulty in resisting distraction and that variance in the ability to resist distraction is also shared with measures of educational attainment. (c) 2015 APA, all rights reserved).

  8. A methodology toward manufacturing grid-based virtual enterprise operation platform

    NASA Astrophysics Data System (ADS)

    Tan, Wenan; Xu, Yicheng; Xu, Wei; Xu, Lida; Zhao, Xianhua; Wang, Li; Fu, Liuliu

    2010-08-01

    Virtual enterprises (VEs) have become one of main types of organisations in the manufacturing sector through which the consortium companies organise their manufacturing activities. To be competitive, a VE relies on the complementary core competences among members through resource sharing and agile manufacturing capacity. Manufacturing grid (M-Grid) is a platform in which the production resources can be shared. In this article, an M-Grid-based VE operation platform (MGVEOP) is presented as it enables the sharing of production resources among geographically distributed enterprises. The performance management system of the MGVEOP is based on the balanced scorecard and has the capacity of self-learning. The study shows that a MGVEOP can make a semi-automated process possible for a VE, and the proposed MGVEOP is efficient and agile.

  9. Optimal resource allocation strategy for two-layer complex networks

    NASA Astrophysics Data System (ADS)

    Ma, Jinlong; Wang, Lixin; Li, Sufeng; Duan, Congwen; Liu, Yu

    2018-02-01

    We study the traffic dynamics on two-layer complex networks, and focus on its delivery capacity allocation strategy to enhance traffic capacity measured by the critical value Rc. With the limited packet-delivering capacity, we propose a delivery capacity allocation strategy which can balance the capacities of non-hub nodes and hub nodes to optimize the data flow. With the optimal value of parameter αc, the maximal network capacity is reached because most of the nodes have shared the appropriate delivery capacity by the proposed delivery capacity allocation strategy. Our work will be beneficial to network service providers to design optimal networked traffic dynamics.

  10. 78 FR 61352 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... shares of FirstSecure Bank and Trust Company, Palos Hill, IL. B. Federal Reserve Bank of Minneapolis..., Julie Jennings, Lone Tree, Colorado, and R. Will Isham, Gordon, Nebraska, in their individual capacities...

  11. Research Stakeholders' Views on Benefits and Challenges for Public Health Research Data Sharing in Kenya: The Importance of Trust and Social Relations.

    PubMed

    Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy; Marsh, Vicki

    2015-01-01

    There is increasing recognition of the importance of sharing research data within the international scientific community, but also of the ethical and social challenges this presents, particularly in the context of structural inequities and varied capacity in international research. Public involvement is essential to building locally responsive research policies, including on data sharing, but little research has involved stakeholders from low-to-middle income countries. Between January and June 2014, a qualitative study was conducted in Kenya involving sixty stakeholders with varying experiences of research in a deliberative process to explore views on benefits and challenges in research data sharing. In-depth interviews and extended small group discussions based on information sharing and facilitated debate were used to collect data. Data were analysed using Framework Analysis, and charting flow and dynamics in debates. The findings highlight both the opportunities and challenges of communicating about this complex and relatively novel topic for many stakeholders. For more and less research-experienced stakeholders, ethical research data sharing is likely to rest on the development and implementation of appropriate trust-building processes, linked to local perceptions of benefits and challenges. The central nature of trust is underpinned by uncertainties around who might request what data, for what purpose and when. Key benefits perceived in this consultation were concerned with the promotion of public health through science, with legitimate beneficiaries defined differently by different groups. Important challenges were risks to the interests of study participants, communities and originating researchers through stigmatisation, loss of privacy, impacting autonomy and unfair competition, including through forms of intentional and unintentional 'misuse' of data. Risks were also seen for science. Given background structural inequities in much international research, building trust in this low-to-middle income setting includes ensuring that the interests of study participants, primary communities and originating researchers will be promoted as far as possible, as well as protected. Important ways of building trust in data sharing include involving the public in policy development and implementation, promoting scientific collaborations around data sharing and building close partnerships between researchers and government health authorities to provide checks and balances on data sharing, and promote near and long-term translational benefits.

  12. Research Stakeholders’ Views on Benefits and Challenges for Public Health Research Data Sharing in Kenya: The Importance of Trust and Social Relations

    PubMed Central

    Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy; Marsh, Vicki

    2015-01-01

    Background There is increasing recognition of the importance of sharing research data within the international scientific community, but also of the ethical and social challenges this presents, particularly in the context of structural inequities and varied capacity in international research. Public involvement is essential to building locally responsive research policies, including on data sharing, but little research has involved stakeholders from low-to-middle income countries. Methods Between January and June 2014, a qualitative study was conducted in Kenya involving sixty stakeholders with varying experiences of research in a deliberative process to explore views on benefits and challenges in research data sharing. In-depth interviews and extended small group discussions based on information sharing and facilitated debate were used to collect data. Data were analysed using Framework Analysis, and charting flow and dynamics in debates. Findings The findings highlight both the opportunities and challenges of communicating about this complex and relatively novel topic for many stakeholders. For more and less research-experienced stakeholders, ethical research data sharing is likely to rest on the development and implementation of appropriate trust-building processes, linked to local perceptions of benefits and challenges. The central nature of trust is underpinned by uncertainties around who might request what data, for what purpose and when. Key benefits perceived in this consultation were concerned with the promotion of public health through science, with legitimate beneficiaries defined differently by different groups. Important challenges were risks to the interests of study participants, communities and originating researchers through stigmatisation, loss of privacy, impacting autonomy and unfair competition, including through forms of intentional and unintentional 'misuse' of data. Risks were also seen for science. Discussion Given background structural inequities in much international research, building trust in this low-to-middle income setting includes ensuring that the interests of study participants, primary communities and originating researchers will be promoted as far as possible, as well as protected. Important ways of building trust in data sharing include involving the public in policy development and implementation, promoting scientific collaborations around data sharing and building close partnerships between researchers and government health authorities to provide checks and balances on data sharing, and promote near and long-term translational benefits. PMID:26331716

  13. KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (center) is welcomed to the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (center) is welcomed to the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  14. Improved Secret Image Sharing Scheme in Embedding Capacity without Underflow and Overflow.

    PubMed

    Pang, Liaojun; Miao, Deyu; Li, Huixian; Wang, Qiong

    2015-01-01

    Computational secret image sharing (CSIS) is an effective way to protect a secret image during its transmission and storage, and thus it has attracted lots of attentions since its appearance. Nowadays, it has become a hot topic for researchers to improve the embedding capacity and eliminate the underflow and overflow situations, which is embarrassing and difficult to deal with. The scheme, which has the highest embedding capacity among the existing schemes, has the underflow and overflow problems. Although the underflow and overflow situations have been well dealt with by different methods, the embedding capacities of these methods are reduced more or less. Motivated by these concerns, we propose a novel scheme, in which we take the differential coding, Huffman coding, and data converting to compress the secret image before embedding it to further improve the embedding capacity, and the pixel mapping matrix embedding method with a newly designed matrix is used to embed secret image data into the cover image to avoid the underflow and overflow situations. Experiment results show that our scheme can improve the embedding capacity further and eliminate the underflow and overflow situations at the same time.

  15. Improved Secret Image Sharing Scheme in Embedding Capacity without Underflow and Overflow

    PubMed Central

    Pang, Liaojun; Miao, Deyu; Li, Huixian; Wang, Qiong

    2015-01-01

    Computational secret image sharing (CSIS) is an effective way to protect a secret image during its transmission and storage, and thus it has attracted lots of attentions since its appearance. Nowadays, it has become a hot topic for researchers to improve the embedding capacity and eliminate the underflow and overflow situations, which is embarrassing and difficult to deal with. The scheme, which has the highest embedding capacity among the existing schemes, has the underflow and overflow problems. Although the underflow and overflow situations have been well dealt with by different methods, the embedding capacities of these methods are reduced more or less. Motivated by these concerns, we propose a novel scheme, in which we take the differential coding, Huffman coding, and data converting to compress the secret image before embedding it to further improve the embedding capacity, and the pixel mapping matrix embedding method with a newly designed matrix is used to embed secret image data into the cover image to avoid the underflow and overflow situations. Experiment results show that our scheme can improve the embedding capacity further and eliminate the underflow and overflow situations at the same time. PMID:26351657

  16. Shared resources : sharing right-of-way for telecommunications : identificaiton, review and analysis of legal and institutional issues

    DOT National Transportation Integrated Search

    1996-04-01

    The advent of fiber-optic communications technology coupled with continued rapid growth in demand for communications capacity have led private communications companies to seek to build new, and extend existing, fiber-optics networks. There is increas...

  17. Evaluating scenarios of locations and capacities for vaccine storage in Nigeria.

    PubMed

    Hirsh Bar Gai, Dor; Graybill, Zachary; Voevodsky, Paule; Shittu, Ekundayo

    2018-06-07

    Many developing countries still face the prevalence of preventable childhood diseases because their vaccine supply chain systems are inadequate by design or structure to meet the needs of their populations. Currently, Nigeria is evaluating options in the redesign of the country's vaccine supply chain. Using Nigeria as a case study, the objective is to evaluate different regional supply chain scenarios to identify the cost minimizing optimal hub locations and storage capacities for doses of different vaccines to achieve a 100% fill rate. First, we employ a shortest-path optimization routine to determine hub locations. Second, we develop a total cost minimizing routine based on stochastic optimization to determine the optimal capacities at the hubs. This model uses vaccine supply data between 2011 and 2014 provided by Nigeria's National Primary Health Care Development Agency (NPHCDA) on Tuberculosis, Polio, Yellow Fever, Tetanus Toxoid, and Hepatitis B. We find that a two-regional system with no central hub (NC2) cut costs by 23% to achieve a 100% fill rate when compared to optimizing the existing chain of six regions with a central hub (EC6). While the government's leading redesign alternative - no central three-hub system (Gov NC3) - reduces costs by 21% compared with the current EC6, it is more expensive than our NC2 system by 3%. In terms of capacity increases, optimizing the current system requires 42% more capacity than our NC2 system. Although the proposed Gov NC3 system requires the least increase in storage capacity, it requires the most distance to achieve a 100% coverage and about 15% more than our NC2. Overall, we find that improving the current system with a central hub and all its variants, even with optimal regional hub locations, require more storage capacities and are costlier than systems without a central hub. While this analysis prescribes the no central hub with two regions (NC2) as the least cost scenario, it is imperative to note that other configurations have benefits and comparative tradeoffs. Our approach and results offer some guidance for future vaccine supply chain redesigns in countries with similar layouts to Nigeria's. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. A thermal storage capacity market for non dispatchable renewable energies

    NASA Astrophysics Data System (ADS)

    Bennouna, El Ghali; Mouaky, Ammar; Arrad, Mouad; Ghennioui, Abdellatif; Mimet, Abdelaziz

    2017-06-01

    Due to the increasingly high capacity of wind power and solar PV in Germany and some other European countries and the high share of variable renewable energy resources in comparison to fossil and nuclear capacity, a power reserve market structured by auction systems was created to facilitate the exchange of balance power capacities between systems and even grid operators. Morocco has a large potential for both wind and solar energy and is engaged in a program to deploy 2000MW of wind capacity by 2020 and 3000 MW of solar capacity by 2030. Although the competitiveness of wind energy is very strong, it appears clearly that the wind program could be even more ambitious than what it is, especially when compared to the large exploitable potential. On the other hand, heavy investments on concentrated solar power plants equipped with thermal energy storage have triggered a few years ago including the launching of the first part of the Nour Ouarzazate complex, the goal being to reach stable, dispatchable and affordable electricity especially during evening peak hours. This paper aims to demonstrate the potential of shared thermal storage capacity between dispatchable and non dispatchable renewable energies and particularly CSP and wind power. Thus highlighting the importance of a storage capacity market in parallel to the power reserve market and the and how it could enhance the development of both wind and CSP market penetration.

  19. Correcting quantum errors with entanglement.

    PubMed

    Brun, Todd; Devetak, Igor; Hsieh, Min-Hsiu

    2006-10-20

    We show how entanglement shared between encoder and decoder can simplify the theory of quantum error correction. The entanglement-assisted quantum codes we describe do not require the dual-containing constraint necessary for standard quantum error-correcting codes, thus allowing us to "quantize" all of classical linear coding theory. In particular, efficient modern classical codes that attain the Shannon capacity can be made into entanglement-assisted quantum codes attaining the hashing bound (closely related to the quantum capacity). For systems without large amounts of shared entanglement, these codes can also be used as catalytic codes, in which a small amount of initial entanglement enables quantum communication.

  20. Reconciliation of the cloud computing model with US federal electronic health record regulations

    PubMed Central

    2011-01-01

    Cloud computing refers to subscription-based, fee-for-service utilization of computer hardware and software over the Internet. The model is gaining acceptance for business information technology (IT) applications because it allows capacity and functionality to increase on the fly without major investment in infrastructure, personnel or licensing fees. Large IT investments can be converted to a series of smaller operating expenses. Cloud architectures could potentially be superior to traditional electronic health record (EHR) designs in terms of economy, efficiency and utility. A central issue for EHR developers in the US is that these systems are constrained by federal regulatory legislation and oversight. These laws focus on security and privacy, which are well-recognized challenges for cloud computing systems in general. EHRs built with the cloud computing model can achieve acceptable privacy and security through business associate contracts with cloud providers that specify compliance requirements, performance metrics and liability sharing. PMID:21727204

  1. The Stellenbosch consensus statement on health promoting schools.

    PubMed

    Macnab, Andrew

    2013-03-01

    Health promotion uses a range of complementary approaches to provide individuals and communities with knowledge that will enable them to improve their own health and wellbeing. Encouraging children to adopt healthy lifestyle habits is a central objective, and health promotion at a community level, particularly through health promoting schools, may be an effective strategy. Health promoting schools are well within the capacity of even poor countries, as they focus on the school and its culture, and establishing health promoting schools requires a change in mindset and refinement of educational investment rather than the provision of major new resources, engagement of non-government organizations or obtaining international funding. A consensus of current evidence and essential concepts underlying health promotion in schools, principles that contribute to success or failure, and opportunities for implementation and engagement is presented, based on shared experience and dialogue at a 2011 international colloquium held at Stellenbosch University.

  2. Wandering tales: evolutionary origins of mental time travel and language

    PubMed Central

    Corballis, Michael C.

    2013-01-01

    A central component of mind wandering is mental time travel, the calling to mind of remembered past events and of imagined future ones. Mental time travel may also be critical to the evolution of language, which enables us to communicate about the non-present, sharing memories, plans, and ideas. Mental time travel is indexed in humans by hippocampal activity, and studies also suggest that the hippocampus in rats is active when the animals replay or pre play activity in a spatial environment, such as a maze. Mental time travel may have ancient origins, contrary to the view that it is unique to humans. Since mental time travel is also thought to underlie language, these findings suggest that language evolved gradually from pre-existing cognitive capacities, contrary to the view of Chomsky and others that language and symbolic thought emerged abruptly, in a single step, within the past 100,000 years. PMID:23908641

  3. Sharing smaller pies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bender, T.

    Depletion of the earth's natural resources is rapidly forcing society to choose values and life styles that will enable survival and well-being for all. Fundamental changes in institutions can be accomplished by developing the self-discipline to limit population and demands. These new values must be adopted: stewardship for growth; austerity for excessive consumption; permanence for profit; responsibilities for rights; people for professions; quality for quantity; sufficiency for affluence; localization for centralization; equity for urbanization; work for leisure; and jobs for machines. People must develop both the capacity for self-sufficiency and the ability to develop interdependent relationships. By studying successful, butmore » less consuming, countries, the U.S. can develop technologies that are fundamentally better and more responsive to scarcity. Evidence exists that smaller scales of operation are better. To accomplish this change, responsibility must be assumed by individuals, communities, governments, and all professional and industrial groups. (17 references) (DCK)« less

  4. Reconciliation of the cloud computing model with US federal electronic health record regulations.

    PubMed

    Schweitzer, Eugene J

    2012-01-01

    Cloud computing refers to subscription-based, fee-for-service utilization of computer hardware and software over the Internet. The model is gaining acceptance for business information technology (IT) applications because it allows capacity and functionality to increase on the fly without major investment in infrastructure, personnel or licensing fees. Large IT investments can be converted to a series of smaller operating expenses. Cloud architectures could potentially be superior to traditional electronic health record (EHR) designs in terms of economy, efficiency and utility. A central issue for EHR developers in the US is that these systems are constrained by federal regulatory legislation and oversight. These laws focus on security and privacy, which are well-recognized challenges for cloud computing systems in general. EHRs built with the cloud computing model can achieve acceptable privacy and security through business associate contracts with cloud providers that specify compliance requirements, performance metrics and liability sharing.

  5. Cultural competence and social relationships: a social network analysis.

    PubMed

    Dauvrin, M; Lorant, V

    2017-06-01

    This study investigated the role of social relationships in the sharing of cultural competence by testing two hypotheses: cultural competence is a socially shared behaviour; and central healthcare professionals are more culturally competent than non-central healthcare professionals. Sustaining cultural competence in healthcare services relies on the assumption that being culturally competent is a socially shared behaviour among health professionals. This assumption has never been tested. Organizational aspects surrounding cultural competence are poorly considered. This therefore leads to a heterogeneous implementation of cultural competence - especially in continental Europe. We carried out a social network analysis in 24 Belgian inpatient and outpatient health services. All healthcare professionals (ego) were requested to fill in a questionnaire (Survey on social relationships of health care professionals) on their level of cultural competence and to identify their professional relationships (alter). We fitted regression models to assess whether (1) at the dyadic level, ego cultural competence was associated with alter cultural competence, and (2) health professionals of greater centrality had greater cultural competence. At the dyadic level, no significant associations were found between ego cultural competence and alter cultural competence, with the exception of subjective exposure to intercultural situations. No significant associations were found between centrality and cultural competence, except for subjective exposure to intercultural situations. Being culturally competent is not a shared behaviour among health professionals. The most central healthcare professionals are not more culturally competent than less central health professionals. Culturally competent health care is not yet a norm in health services. Health care and training authorities should either make cultural competent health care a licensing criteria or reward culturally competent health care. © 2016 The Authors International Nursing Review published by John Wiley & Sons Ltd on behalf of International Council of Nurses.

  6. Periodic variation in physical and chemical properties of two central Washington soils.

    Treesearch

    Tom D. Anderson; Arthur R. Tiedemann

    1970-01-01

    Soils derived from two widely distributed parent materials in central Washington were examined periodically during 1968-69 for physical and chemical properties. Basalt soils showed significant periodic variation in cation exchange capacity, pH, and Na and K contents. In sandstone soils, cation exchange capacity and Ca, Na, and K contents varied significantly among...

  7. The use of abstract paintings and narratives to foster reflective capacity in medical educators: a multinational faculty development workshop

    PubMed Central

    Karkabi, Khaled; Wald, Hedy S; Cohen Castel, Orit

    2014-01-01

    Reflective capacity is integral to core healthcare professional practice competencies. Reflection plays a central role in teacher education as reflecting on teaching behaviours with critical analysis can potentially improve teaching practice. The humanities including narrative and the visual arts can serve as a valuable tool for fostering reflection. We conducted a multinational faculty development workshop aiming to enhance reflective capacity in medical educators by using a combination of abstract paintings and narratives. Twenty-three family physicians or physicians-in-training from 10 countries participated in the workshop. Qualitative assessment of the workshop showed that the combined use of art and narrative was well received and perceived as contributing to the reflective exercise. Participants generally felt that viewing abstract paintings had facilitated a valuable mood transformation and prepared them emotionally for the reflective writing. Our analysis found that the following themes emerged from participants’ responses: (1) narratives from different countries are similar; (2) the use of art helped access feelings; (3) viewing abstract paintings facilitated next steps; (4) writing reflective narratives promoted examination of educational challenges, compassion for self and other, and building an action plan; and (5) sharing of narrative was helpful for fostering active listening and appreciating multiple perspectives. Future research might include comparing outcomes for a group participating in arts–narrative-based workshops with those of a control group using only reflective narrative or in combination with figurative art, and implementing a combination of qualitative and quantitative methods of assessment. PMID:24273319

  8. Building Interdisciplinary Research Capacity: a Key Challenge for Ecological Approaches in Public Health.

    PubMed

    Galway, Lindsay P; Parkes, Margot W; Allen, Diana; Takaro, Tim K

    2016-01-01

    The shortcomings of public health research informed by reductionist and fragmented biomedical approaches and the emergence of wicked problems are fueling a renewed interest in ecological approaches in public health. Despite the central role of interdisciplinarity in the context of ecological approaches in public health research, inadequate attention has been given to the specific challenge of doing interdisciplinary research in practice. As a result, important knowledge gaps exist with regards to the practice of interdisciplinary research. We argue that explicit attention towards the challenge of doing interdisciplinary research is critical in order to effectively apply ecological approaches to public health issues. This paper draws on our experiences developing and conducting an interdisciplinary research project exploring the links among climate change, water, and health to highlight five specific insights which we see as relevant to building capacity for interdisciplinary research specifically, and which have particular relevance to addressing the integrative challenges demanded by ecological approaches to address public health issues. These lessons include: (i) the need for frameworks that facilitate integration; (ii) emphasize learning-by-doing; (iii) the benefits of examining issues at multiple scales; (iv) make the implicit, explicit; and (v) the need for reflective practice. By synthesizing and sharing experiences gained by engaging in interdisciplinary inquiries using an ecological approach, this paper responds to a growing need to build interdisciplinary research capacity as a means for advancing the ecological public health agenda more broadly.

  9. Building Interdisciplinary Research Capacity: a Key Challenge for Ecological Approaches in Public Health

    PubMed Central

    Galway, Lindsay P.; Parkes, Margot W.; Allen, Diana; Takaro, Tim K.

    2016-01-01

    The shortcomings of public health research informed by reductionist and fragmented biomedical approaches and the emergence of wicked problems are fueling a renewed interest in ecological approaches in public health. Despite the central role of interdisciplinarity in the context of ecological approaches in public health research, inadequate attention has been given to the specific challenge of doing interdisciplinary research in practice. As a result, important knowledge gaps exist with regards to the practice of interdisciplinary research. We argue that explicit attention towards the challenge of doing interdisciplinary research is critical in order to effectively apply ecological approaches to public health issues. This paper draws on our experiences developing and conducting an interdisciplinary research project exploring the links among climate change, water, and health to highlight five specific insights which we see as relevant to building capacity for interdisciplinary research specifically, and which have particular relevance to addressing the integrative challenges demanded by ecological approaches to address public health issues. These lessons include: (i) the need for frameworks that facilitate integration; (ii) emphasize learning-by-doing; (iii) the benefits of examining issues at multiple scales; (iv) make the implicit, explicit; and (v) the need for reflective practice. By synthesizing and sharing experiences gained by engaging in interdisciplinary inquiries using an ecological approach, this paper responds to a growing need to build interdisciplinary research capacity as a means for advancing the ecological public health agenda more broadly. PMID:29546171

  10. IHE profiles applied to regional PACS.

    PubMed

    Fernandez-Bayó, Josep

    2011-05-01

    PACS has been widely adopted as an image storage solution that perfectly fits the radiology department workflow and that can be easily extended to other hospital departments. Integrations with other hospital systems, like the Radiology Information System, the Hospital Information System and the Electronic Patient Record are fully achieved but still challenging aims. PACS also creates the perfect environment for teleradiology and teleworking setups. One step further is the regional PACS concept where different hospitals or health care enterprises share the images in an integrated Electronic Patient Record. Among the different solutions available to share images between different hospitals IHE (Integrating the Healthcare Enterprise) organization presents the Cross Enterprise Document Sharing profile (XDS) which allows sharing images from different hospitals even if they have different PACS vendors. Adopting XDS has multiple advantages, images do not need to be duplicated in a central archive to be shared among the different healthcare enterprises, they only need to be indexed and published in a central document registry. In the XDS profile IHE defines the mechanisms to publish and index the images in the central document registry. It also defines the mechanisms that each hospital will use to retrieve those images regardless on the Hospital PACS they are stored. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  11. Army Investment Casting Industry Report

    DTIC Science & Technology

    1987-04-01

    Page 9 #5 Capacity Utilization Rates Page 10 #6 Labor Intensity Indicator Page 11 #7 Market Share By Firm Size Page 12 #8 Market Share By Type of Firm...information gathered from the U.S. casters. These similarities coupled with the relatively small Canadian market share resulted in similar conclusions...investment castings further expanding into the Defense market some foreseeable difficulties that could arise would be: a. Lack of adequate tooling. b

  12. Regionalization of municipal solid waste management in Japan: balancing the proximity principle with economic efficiency.

    PubMed

    Okuda, Itaru; Thomson, Vivian E

    2007-07-01

    The proximity principle - disposing of waste close to its origin - has been a central value in municipal solid waste (MSW) management in Japan for the last 30 years and its widespread adoption has helped resolve numerous "Not in My Backyard" issues related to MSW management. However, MSW management costs have soared, in large part because of aggressive recycling efforts and because most MSW is incinerated in a country that has scarce landfill capacity. In addition, smaller, less sophisticated incinerators have been closed because of high dioxin emissions. Rising costs combined with the closure of smaller incinerators have shifted MSW management policy toward regionalization, which is the sharing of waste management facilities across municipalities. Despite the increased use of regionalized MSW facilities, the proximity principle remains the central value in Japanese MSW management. Municipal solid waste management has become increasingly regionalized in the United States, too, but different driving forces are at work in these two countries. The transition to regionalized MSW management in Japan results from strong governmental control at all levels, with the central government providing funds and policy direction and prefectures and municipalities being the primary implementing authorities. By contrast, market forces are a much stronger force with US MSW management, where local governments - with state government oversight - have primary responsibility for MSW management. We describe recent changes in Japan's MSW programs. We examine the connections between MSW facility regionalization, on the one hand, and, on the other hand, the proximity principle, coordination among local governments, central government control, and financing mechanisms.

  13. Global mental health: transformative capacity building in Nicaragua

    PubMed Central

    Sapag, Jaime C.; Herrera, Andrés; Trainor, Ruth; Caldera, Trinidad; Khenti, Akwatu

    2013-01-01

    Background Mental health is increasingly recognised as integral to good public health, but this area continues to lack sufficient planning, resources, and global strategy. It is a pressing concern in Latin America, where social determinants of health aggravate existing inequities in access to health services. Nicaragua faces serious mental health needs and challenges. One key strategy for addressing gaps in mental health services is building capacity at the primary healthcare and system levels. Objective Using the framework of best practice literature, this article analyses the four-year collaborative process between the National Autonomous University of Nicaragua in León (UNAN-León) and the Centre for Addiction and Mental Health (CAMH) in Canada, which is aimed at improving mental healthcare in Nicaragua. Design Based on a critical analysis of evaluation reports, key documents, and discussion among partners, the central steps of the collaboration are analysed and main successes and challenges identified. Results A participatory needs assessment identified local strengths and weaknesses, expected outcomes regarding competencies, and possible methodologies and recommendations for the development of a comprehensive capacity-building programme. The partners delivered two international workshops on mental health and addiction with an emphasis on primary healthcare. More recently, an innovative Diploma and Master programme was launched to foster interprofessional leadership and effective action to address mental health and addiction needs. Collaborative activities have taken place in Nicaragua and Canada. Discussion To date, international collaboration between Nicaragua and CAMH has been successful in achieving the jointly defined goals. The process has led to mutual knowledge sharing, strong networking, and extensive educational opportunities. Evidence of effective and respectful global health capacity building is provided. Lessons learned and implications for global health action are identified and discussed. PMID:24088364

  14. Interprofessional simulated learning: short-term associations between simulation and interprofessional collaboration

    PubMed Central

    2011-01-01

    Background Health professions education programs use simulation for teaching and maintaining clinical procedural skills. Simulated learning activities are also becoming useful methods of instruction for interprofessional education. The simulation environment for interprofessional training allows participants to explore collaborative ways of improving communicative aspects of clinical care. Simulation has shown communication improvement within and between health care professions, but the impacts of teamwork simulation on perceptions of others' interprofessional practices and one's own attitudes toward teamwork are largely unknown. Methods A single-arm intervention study tested the association between simulated team practice and measures of interprofessional collaboration, nurse-physician relationships, and attitudes toward health care teams. Participants were 154 post-licensure nurses, allied health professionals, and physicians. Self- and proxy-report survey measurements were taken before simulation training and two and six weeks after. Results Multilevel modeling revealed little change over the study period. Variation in interprofessional collaboration and attitudes was largely attributable to between-person characteristics. A constructed categorical variable indexing 'leadership capacity' found that participants with highest and lowest values were more likely to endorse shared team leadership over physician centrality. Conclusion Results from this study indicate that focusing interprofessional simulation education on shared leadership may provide the most leverage to improve interprofessional care. PMID:21443779

  15. KSC-04PD-0254

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. KSC Director Jim Kennedy makes a presentation to NASA and other officials about the benefits of locating NASAs new Shared Services Center in the Central Florida Research Park, near Orlando. At the far left is Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  16. Use of nontraditional flight displays for the reduction of central visual overload in the cockpit

    NASA Technical Reports Server (NTRS)

    Weinstein, Lisa F.; Wickens, Christopher D.

    1992-01-01

    The use of nontraditional flight displays to reduce visual overload in the cockpit was investigated in a dual-task paradigm. Three flight displays (central, peripheral, and ecological) were used between subjects for the primary tasks, and the type of secondary task (object identification or motion judgment) and the presentation of the location of the task in the visual field (central or peripheral) were manipulated with groups. The two visual-spatial tasks were time-shared to study the possibility of a compatibility mapping between task type and task location. The ecological display was found to allow for the most efficient time-sharing.

  17. Realizing Shared Services--A Punctuated Process Analysis of a Public IT Department

    ERIC Educational Resources Information Center

    Olsen, Timothy John

    2012-01-01

    IT services are increasingly being offered via a shared service model. This model promises the benefits of centralization and consolidation, as well as an increased customer satisfaction. Adopting shared services is not easy as it necessitates a major organizational change, with few documented exemplars to guide managers. This research explores a…

  18. Distributed generation of shared RSA keys in mobile ad hoc networks

    NASA Astrophysics Data System (ADS)

    Liu, Yi-Liang; Huang, Qin; Shen, Ying

    2005-12-01

    Mobile Ad Hoc Networks is a totally new concept in which mobile nodes are able to communicate together over wireless links in an independent manner, independent of fixed physical infrastructure and centralized administrative infrastructure. However, the nature of Ad Hoc Networks makes them very vulnerable to security threats. Generation and distribution of shared keys for CA (Certification Authority) is challenging for security solution based on distributed PKI(Public-Key Infrastructure)/CA. The solutions that have been proposed in the literature and some related issues are discussed in this paper. The solution of a distributed generation of shared threshold RSA keys for CA is proposed in the present paper. During the process of creating an RSA private key share, every CA node only has its own private security. Distributed arithmetic is used to create the CA's private share locally, and that the requirement of centralized management institution is eliminated. Based on fully considering the Mobile Ad Hoc network's characteristic of self-organization, it avoids the security hidden trouble that comes by holding an all private security share of CA, with which the security and robustness of system is enhanced.

  19. Provision of CT Scanning Capability to VA/DoD (Veterans Administration/ Department of Defense) Health Care Facilities through a Shared Mobile CT Unit: A Feasibility Study

    DTIC Science & Technology

    1984-07-27

    all Federal sectoT facilities. Shared services have long been recna, nzed as one way to reduce costs, throuph optima’ itilizaticn of capacity, but...stock arguments against shared services . A CT scanner may be installed in a mobile van and the service moved in its entirety from hospital to hospital...annually. This severely restricted further acquisition by hospitals in most health service areas (5,9,14). Shared Services : A Response to Regulation

  20. Can job sharing work for nurse managers?

    PubMed

    Dubourg, Laurence; Ahmling, Janette A; Bujas, Lenka

    2006-02-01

    Addressing employer reluctance to employ nurse managers in a job-sharing capacity, the aim of this paper is to explore job sharing among nurse managers. The literature highlighted potential fragmentation of leadership, breakdown of communication and higher costs as issues, with the retention of experienced highly motivated managers identified as an advantage. A staff survey explored whether the job-sharing arrangement trialled in a day surgery setting by two nurse managers was successful compared with similar roles held by full-time managers. This paper suggests that nurse managers can successfully job share. Overall, this paper recommends that employers consider a job-sharing arrangement when they wish to retain experienced nurse managers, and highlights aspects that can enhance a successful outcome.

  1. The Cultural Ecogram: A Tool for Enhancing Culturally Anchored Shared Understanding in the Treatment of Ethnic Minority Families

    PubMed Central

    YASUI, MIWA

    2015-01-01

    Ethnic and racial disparities in mental health care continue to exist, highlighting the increasing concern within the realm of clinical practice as to how clinicians are to effectively integrate the central role of culture and context into the treatment delivery process for culturally diverse children and families. The current paper presents the Cultural Ecogram, - a clinical engagement tool designed to facilitate the development of a culturally anchored shared understanding – as one method that may facilitate clinician-client shared understanding on the client’s cultural, ethnic and racial context central to the effective implementation of treatments with ethnic minority children and families. PMID:26273233

  2. Pieces of Civic Intelligence: Towards a Capacities Framework

    ERIC Educational Resources Information Center

    Schuler, Douglas

    2014-01-01

    Civic intelligence is the capacity of collectivities--from small informal groups to humanity as a whole--to equitably and effectively address important shared problems such as poverty, bioterrorism, and natural disasters. It's an abstract concept that can be expressed in policy, art, demonstrations, or conversation. In this article, civic…

  3. KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (left) greets U.S. Representative Ric Keller during a tour of the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (left) greets U.S. Representative Ric Keller during a tour of the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  4. KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (right) greets Florida Congressman Tom Feeney during a tour of the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (right) greets Florida Congressman Tom Feeney during a tour of the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  5. Does working memory capacity predict cross-modally induced failures of awareness?

    PubMed

    Kreitz, Carina; Furley, Philip; Simons, Daniel J; Memmert, Daniel

    2016-01-01

    People often fail to notice unexpected stimuli when they are focusing attention on another task. Most studies of this phenomenon address visual failures induced by visual attention tasks (inattentional blindness). Yet, such failures also occur within audition (inattentional deafness), and people can even miss unexpected events in one sensory modality when focusing attention on tasks in another modality. Such cross-modal failures are revealing because they suggest the existence of a common, central resource limitation. And, such central limits might be predicted from individual differences in cognitive capacity. We replicated earlier evidence, establishing substantial rates of inattentional deafness during a visual task and inattentional blindness during an auditory task. However, neither individual working memory capacity nor the ability to perform the primary task predicted noticing in either modality. Thus, individual differences in cognitive capacity did not predict failures of awareness even though the failures presumably resulted from central resource limitations. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. The evolutionary biology of musical rhythm: was Darwin wrong?

    PubMed

    Patel, Aniruddh D

    2014-03-01

    In The Descent of Man, Darwin speculated that our capacity for musical rhythm reflects basic aspects of brain function broadly shared among animals. Although this remains an appealing idea, it is being challenged by modern cross-species research. This research hints that our capacity to synchronize to a beat, i.e., to move in time with a perceived pulse in a manner that is predictive and flexible across a broad range of tempi, may be shared by only a few other species. Is this really the case? If so, it would have important implications for our understanding of the evolution of human musicality.

  7. The Evolutionary Biology of Musical Rhythm: Was Darwin Wrong?

    PubMed Central

    Patel, Aniruddh D.

    2014-01-01

    In The Descent of Man, Darwin speculated that our capacity for musical rhythm reflects basic aspects of brain function broadly shared among animals. Although this remains an appealing idea, it is being challenged by modern cross-species research. This research hints that our capacity to synchronize to a beat, i.e., to move in time with a perceived pulse in a manner that is predictive and flexible across a broad range of tempi, may be shared by only a few other species. Is this really the case? If so, it would have important implications for our understanding of the evolution of human musicality. PMID:24667562

  8. Partnership to build research capacity.

    PubMed

    Boland, Mary G; Kamikawa, Cindy; Inouye, Jillian; Latimer, Renee W; Marshall, Stephanie

    2010-01-01

    Today's nursing leaders are setting the stage for the next evolution--bringing together skilled clinicians and administrators with peers in education to create new approaches to leading the profession forward. Partnerships share goals, common purpose, mutual respect, willingness to negotiate and compromise, informed participation, information giving, and shared decision making. The shared practice academia effort between a public university and a private health care system situated in the island state of Hawai'i is described. The medical center and school of nursing pursued individual strategic efforts to build research capacity and used the opportunity to fund academic practice research projects. The mutual need and recognition of the high stakes involved, in concert with stable, committed leaders at all levels, were key to the early success of their efforts. Through the formal research partnership mechanism, a discrete focus was created for efforts and used to move to tactical, operational, and interpersonal integration in this relationship.

  9. The highs and lows of theoretical interpretation in animal-metacognition research

    PubMed Central

    Smith, J. David; Couchman, Justin J.; Beran, Michael J.

    2012-01-01

    Humans feel uncertain. They know when they do not know. These feelings and the responses to them ground the research literature on metacognition. It is a natural question whether animals share this cognitive capacity, and thus animal metacognition has become an influential research area within comparative psychology. Researchers have explored this question by testing many species using perception and memory paradigms. There is an emerging consensus that animals share functional parallels with humans’ conscious metacognition. Of course, this research area poses difficult issues of scientific inference. How firmly should we hold the line in insisting that animals’ performances are low-level and associative? How high should we set the bar for concluding that animals share metacognitive capacities with humans? This area offers a constructive case study for considering theoretical problems that often confront comparative psychologists. The authors present this case study and address diverse issues of scientific judgement and interpretation within comparative psychology. PMID:22492748

  10. Voice, (inter-)subjectivity, and real time recurrent interaction

    PubMed Central

    Cummins, Fred

    2014-01-01

    Received approaches to a unified phenomenon called “language” are firmly committed to a Cartesian view of distinct unobservable minds. Questioning this commitment leads us to recognize that the boundaries conventionally separating the linguistic from the non-linguistic can appear arbitrary, omitting much that is regularly present during vocal communication. The thesis is put forward that uttering, or voicing, is a much older phenomenon than the formal structures studied by the linguist, and that the voice has found elaborations and codifications in other domains too, such as in systems of ritual and rite. Voice, it is suggested, necessarily gives rise to a temporally bound subjectivity, whether it is in inner speech (Descartes' “cogito”), in conversation, or in the synchronized utterances of collective speech found in prayer, protest, and sports arenas world wide. The notion of a fleeting subjective pole tied to dynamically entwined participants who exert reciprocal influence upon each other in real time provides an insightful way to understand notions of common ground, or socially shared cognition. It suggests that the remarkable capacity to construct a shared world that is so characteristic of Homo sapiens may be grounded in this ability to become dynamically entangled as seen, e.g., in the centrality of joint attention in human interaction. Empirical evidence of dynamic entanglement in joint speaking is found in behavioral and neuroimaging studies. A convergent theoretical vocabulary is now available in the concept of participatory sense-making, leading to the development of a rich scientific agenda liberated from a stifling metaphysics that obscures, rather than illuminates, the means by which we come to inhabit a shared world. PMID:25101028

  11. Teachers Rally around Writing: Shared Leadership Transforms Low-Performing Colorado Elementary

    ERIC Educational Resources Information Center

    Frazee, Dana; Frunzi, Kay; Hein, Heather

    2013-01-01

    To improve the quality of instruction and the achievement of all students, effective school leaders develop capacity, advocate, and create support systems for professional learning. Creating a team of teachers to share leadership, responsibility, and accountability for achieving collective goals is essential. This was the task of a first-time…

  12. 7 CFR 701.105 - Land eligibility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... is the subject of the cost share: (1) Will have new conservation problems caused as a result of a... productive capacity of the land; (iii) Represent unusual damage that, except for wind erosion, is not of the... existing prior to the disaster are not eligible for cost-share assistance. (2) Be physically located in a...

  13. 7 CFR 701.105 - Land eligibility.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... is the subject of the cost share: (1) Will have new conservation problems caused as a result of a... productive capacity of the land; (iii) Represent unusual damage that, except for wind erosion, is not of the... existing prior to the disaster are not eligible for cost-share assistance. (2) Be physically located in a...

  14. 7 CFR 701.105 - Land eligibility.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... is the subject of the cost share: (1) Will have new conservation problems caused as a result of a... productive capacity of the land; (iii) Represent unusual damage that, except for wind erosion, is not of the... existing prior to the disaster are not eligible for cost-share assistance. (2) Be physically located in a...

  15. 7 CFR 701.105 - Land eligibility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... is the subject of the cost share: (1) Will have new conservation problems caused as a result of a... productive capacity of the land; (iii) Represent unusual damage that, except for wind erosion, is not of the... existing prior to the disaster are not eligible for cost-share assistance. (2) Be physically located in a...

  16. A Point to Share: Streamlining Access Services Workflow through Online Collaboration, Communication, and Storage with Microsoft SharePoint

    ERIC Educational Resources Information Center

    Diffin, Jennifer; Chirombo, Fanuel; Nangle, Dennis; de Jong, Mark

    2010-01-01

    This article explains how the document management team (circulation and interlibrary loan) at the University of Maryland University College implemented Microsoft's SharePoint product to create a central hub for online collaboration, communication, and storage. Enhancing the team's efficiency, organization, and cooperation was the primary goal.…

  17. Benefit of adaptive FEC in shared backup path protected elastic optical network.

    PubMed

    Guo, Hong; Dai, Hua; Wang, Chao; Li, Yongcheng; Bose, Sanjay K; Shen, Gangxiang

    2015-07-27

    We apply an adaptive forward error correction (FEC) allocation strategy to an Elastic Optical Network (EON) operated with shared backup path protection (SBPP). To maximize the protected network capacity that can be carried, an Integer Linear Programing (ILP) model and a spectrum window plane (SWP)-based heuristic algorithm are developed. Simulation results show that the FEC coding overhead required by the adaptive FEC scheme is significantly lower than that needed by a fixed FEC allocation strategy resulting in higher network capacity for the adaptive strategy. The adaptive FEC allocation strategy can also significantly outperform the fixed FEC allocation strategy both in terms of the spare capacity redundancy and the average FEC coding overhead needed per optical channel. The proposed heuristic algorithm is efficient and not only performs closer to the ILP model but also does much better than the shortest-path algorithm.

  18. Building Capacity through International Student Affairs Exchange

    ERIC Educational Resources Information Center

    Roberts, Dennis C.; Roberts, Darbi L.

    2012-01-01

    In order to build local capacity in an international higher education setting, the Qatar Study Tour and Young Professionals Institute (QST and YPI) was created as an inquiry-based learning experience shared among diverse participants and designed to enhance learning at both the local and international levels. The intent of the QST and YPI model…

  19. 78 FR 6382 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... shares other than 100.\\8\\ Moreover, the concept of listing and trading parallel options products of... terms of the Options Disclosure Document. With regard to the impact of this proposal on system capacity... Authority (``OPRA'') have the necessary systems capacity to handle the potential additional traffic...

  20. A Formal Model of Capacity Limits in Working Memory

    ERIC Educational Resources Information Center

    Oberauer, Klaus; Kliegl, Reinhold

    2006-01-01

    A mathematical model of working-memory capacity limits is proposed on the key assumption of mutual interference between items in working memory. Interference is assumed to arise from overwriting of features shared by these items. The model was fit to time-accuracy data of memory-updating tasks from four experiments using nonlinear mixed effect…

  1. A Comprehensive and Cost-Effective Computer Infrastructure for K-12 Schools

    NASA Technical Reports Server (NTRS)

    Warren, G. P.; Seaton, J. M.

    1996-01-01

    Since 1993, NASA Langley Research Center has been developing and implementing a low-cost Internet connection model, including system architecture, training, and support, to provide Internet access for an entire network of computers. This infrastructure allows local area networks which exceed 50 machines per school to independently access the complete functionality of the Internet by connecting to a central site, using state-of-the-art commercial modem technology, through a single standard telephone line. By locating high-cost resources at this central site and sharing these resources and their costs among the school districts throughout a region, a practical, efficient, and affordable infrastructure for providing scale-able Internet connectivity has been developed. As the demand for faster Internet access grows, the model has a simple expansion path that eliminates the need to replace major system components and re-train personnel. Observations of optical Internet usage within an environment, particularly school classrooms, have shown that after an initial period of 'surfing,' the Internet traffic becomes repetitive. By automatically storing requested Internet information on a high-capacity networked disk drive at the local site (network based disk caching), then updating this information only when it changes, well over 80 percent of the Internet traffic that leaves a location can be eliminated by retrieving the information from the local disk cache.

  2. Community Capacity Building.

    ERIC Educational Resources Information Center

    McGinty, Sue

    As community assets, schools are central to community development and are best suited to provide a learning community that can build the whole community's capacity to address educational disadvantage. Community capacity building means strengthening a community's ability to become self-reliant by increasing social cohesion and social capital. In…

  3. An Efficient Multiparty Quantum Secret Sharing Protocol Based on Bell States in the High Dimension Hilbert Space

    NASA Astrophysics Data System (ADS)

    Gao, Gan; Wang, Li-Ping

    2010-11-01

    We propose a quantum secret sharing protocol, in which Bell states in the high dimension Hilbert space are employed. The biggest advantage of our protocol is the high source capacity. Compared with the previous secret sharing protocol, ours has the higher controlling efficiency. In addition, as decoy states in the high dimension Hilbert space are used, we needn’t destroy quantum entanglement for achieving the goal to check the channel security.

  4. Systematic revision of the marbled velvet geckos (Oedura marmorata species complex, Diplodactylidae) from the Australian arid and semi-arid zones.

    PubMed

    Oliver, Paul M; Doughty, Paul

    2016-03-08

    Lizards restricted to rocky habitats often comprise numerous deeply divergent lineages, reflecting the disjunct nature of their preferred habitat and the capacity of rocky habitats to function as evolutionary refugia. Here we review the systematics and diversity of the predominantly saxicoline Australian marbled velvet geckos (genus Oedura) in the Australian arid and semi-arid zones using newly-gathered morphological data and previously published genetic data. Earlier work showed that four largely allopatric and genetically divergent lineages are present: Western (Pilbara and Gascoyne regions), Gulf (west and south of the Gulf of Carpentaria), Central (central ranges) and Eastern (Cooper and Darling Basins). None of these four populations are conspecific with true O. marmorata, a seperate species complex that is restricted to the Top End region of the Northern Territory. Top End forms share a short, bulbous tail whereas the other four lineages treated here possess a long, tapering tail. Morphological differences among the arid and semi-arid lineages include smaller body size, tapering lamellae and a shorter tail for the Gulf population, and a partially divided rostral scale in the Western population compared to the Central and Eastern populations. Accordingly, we resurrect O. cincta de Vis from synonymy for the Central and Eastern lineages, and regard this species as being comprised of two evolutionary significant units. We also describe the Gulf and Western lineages as new species: Oedura bella sp. nov. and O. fimbria sp. nov., respectively. We note that a predominantly arboreal lineage (the Eastern lineage of O. cincta) is more widely distributed than the other lineages and is phylogenetically nested within a saxicoline clade, but tends to have a deeper head and shorter limbs, consistent with morphological variation observed in other lizard radiations including both saxicoline and arboreal taxa.

  5. Positivity, discontinuity, finite resources, and nonzero error for arbitrarily varying quantum channels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boche, H., E-mail: boche@tum.de, E-mail: janis.noetzel@tum.de; Nötzel, J., E-mail: boche@tum.de, E-mail: janis.noetzel@tum.de

    2014-12-15

    This work is motivated by a quite general question: Under which circumstances are the capacities of information transmission systems continuous? The research is explicitly carried out on finite arbitrarily varying quantum channels (AVQCs). We give an explicit example that answers the recent question whether the transmission of messages over AVQCs can benefit from assistance by distribution of randomness between the legitimate sender and receiver in the affirmative. The specific class of channels introduced in that example is then extended to show that the unassisted capacity does have discontinuity points, while it is known that the randomness-assisted capacity is always continuousmore » in the channel. We characterize the discontinuity points and prove that the unassisted capacity is always continuous around its positivity points. After having established shared randomness as an important resource, we quantify the interplay between the distribution of finite amounts of randomness between the legitimate sender and receiver, the (nonzero) probability of a decoding error with respect to the average error criterion and the number of messages that can be sent over a finite number of channel uses. We relate our results to the entanglement transmission capacities of finite AVQCs, where the role of shared randomness is not yet well understood, and give a new sufficient criterion for the entanglement transmission capacity with randomness assistance to vanish.« less

  6. The Empathetic School

    ERIC Educational Resources Information Center

    Tomlinson, Carol Ann; Murphy, Michael

    2018-01-01

    Carol Ann Tomlinson and Michael Murphy explore how educators can create an empathetic school--"a place where our central and shared goal was to understand the experiences and perspectives of those who share our space and making decisions based on what would serve them best."

  7. Integrating art and science: A case study of middle school reform

    NASA Astrophysics Data System (ADS)

    Smar, Benedict J.

    2000-10-01

    Schools are under tremendous pressure to change and improve. Among the many strategies advocated to improve learning is that of curriculum integration. For arts advocates, that translates into an interest in integrating the arts into the curriculum. While the arts have never been at the forefront of America's educational priorities, recent rhetoric, policy, and research suggested they are more a part of mainstream educational reform policy at this time. However, while current policy and the literature support a strong role for the arts in education, practice may be more influenced by the variety of complex, powerful issues faced by schools as organizations engaged in navigating the turbulent waters of change. The juxtaposition of these factors, along with limited empirical data about the practical considerations of arts integration in the context of change, created a need to know more about the practicalities of integrating the arts into the curriculum. The purpose of this study was to examine the practical considerations which surround integrating art and science at the middle school level. A case study design was employed which used qualitative methods to gather data including interviews, informal conversations, direct observations, and the examination of artifacts. Data were analyzed using a theoretically grounded, Capacity Analysis Model developed through review of the literature. The findings indicated that integrating the arts into the curriculum must be considered in light of the broader context of educational change. The school's capacity to deal with change is central to the integrative process. Building capacity on individual, cultural, structural, and environmental levels facilitated an emergent link between art and science. The process was interactive and complex. The continuous interaction and synthesis of the four capacities manifested itself as the school's integrative capacity. It was concluded that building the capacity to address change, engaging in meaningful dialogue, collaborating in curriculum planning, developing common teaching practices and definitions, integrating the people, sharing ownership of curriculum, and active participation of the art teacher in the process are critical elements when considering the practical side of integrating the arts into the curriculum.

  8. KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (center) listens to Congressman Tom Feeney (second from left) during a tour of the Central Florida Research Park, near Orlando. At right is U.S. Congressman Dave Weldon. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA Administrator Sean O’Keefe (center) listens to Congressman Tom Feeney (second from left) during a tour of the Central Florida Research Park, near Orlando. At right is U.S. Congressman Dave Weldon. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  9. Group learning capacity: the roles of open-mindedness and shared vision

    PubMed Central

    Lord, Mimi

    2015-01-01

    Open-mindedness (OPM) is a construct that is considered a key foundational aspect of learning in individuals, groups and organizations. Also known as critical inquiry or reflection, OPM is believed to increase learning through examination of prior beliefs, decisions and mistakes, and also through openness to new ideas. Renowned theorists including Dewey and Argyris have emphasized the relationship between OPM and learning, yet little quantitative research has tested it or examined moderators of the linkage. The setting for the current study is that of endowment investment committees at U.S. universities and colleges who need to make knowledgeable and well-reasoned decisions about the composition of investment portfolios. Findings indicate that OPM has a positive, significant effect on group learning capacity (LCAP) and also that shared vision, which represents the group's collective purpose and direction, moderates that relationship. The literature review and discussion offer insights about how OPM is related to the research on group conflict, and how shared vision (SHV) differs from concepts such as interpersonal cohesiveness and conformity that have been associated with groupthink. A review of relevant research from the fields of organizational learning, group dynamics, and absorptive capacity provides context for the development of the hypotheses and the discussion of findings. PMID:25774141

  10. Making a Difference: The Future of HPT in Sustaining Best-Practice International Capacity Development

    ERIC Educational Resources Information Center

    Kelly, Steven J.; Coughlin, Patrick C.; Novak, M. Mari

    2012-01-01

    Over the past decade, human performance technology (HPT) has become an important source of rigor and application in support of best practices in capacity development. HPT shares common principles with the Organisation for Economic Co-operation and Development best practices. This article explores HPT's critical role as the methodology of choice…

  11. Enumeration of Objects and Substances in Non-Human Primates: Experiments with Brown Lemurs ("Eulemur Fulvus")

    ERIC Educational Resources Information Center

    Mahajan, Neha; Barnes, Jennifer L.; Blanco, Marissa; Santos, Laurie R.

    2009-01-01

    Both human infants and adult non-human primates share the capacity to track small numbers of objects across time and occlusion. The question now facing developmental and comparative psychologists is whether similar mechanisms give rise to this capacity across the two populations. Here, we explore whether non-human primates' object tracking…

  12. Within Connections: Empathy, Mirror Neurons, and Art Education

    ERIC Educational Resources Information Center

    Jeffers, Carol S.

    2009-01-01

    The capacity for empathy is important to the human community, and the art classroom provides a unique environment in which this capacity can be developed. Connections to objects of art and material culture, as forged by individual students and also shared with classmates, can be as empathic as they are meaningful. An openness to others and their…

  13. An Analysis of Medical Imaging Costs in Military Treatment Facilities

    DTIC Science & Technology

    2014-09-01

    authority to completely control the medical systems of each service, the DHA 7 was given management responsibility for specific shared services , functions...efficient health operations through enhanced enterprise-wide shared services . • Deliver more comprehensive primary care and integrated health...of shared services that will fall under central control: • facility planning • medical logistics • health information technology • Tricare health

  14. Achievement Goal Orientations and Identity Formation Styles

    ERIC Educational Resources Information Center

    Kaplan, Avi; Flum, Hanoch

    2010-01-01

    The present article points to shared underlying theoretical assumptions and central processes of a prominent academic motivation perspective--achievement goal theory--and recent process perspectives in the identity formation literature, and more specifically, identity formation styles. The review highlights the shared definition of achievement…

  15. E-Content Capacity Development--RUFORUM Network Experiences

    ERIC Educational Resources Information Center

    Dhlamini, Nodumo

    2011-01-01

    The Regional Universities Forum for Capacity Building in Agriculture (RUFORUM), established in 2004, is a network of 25 universities at the postgraduate level in 15 countries in Eastern, Central, and Southern Africa. RUFORUM's mission is to strengthen the capacity of universities to foster innovations responsive to demands of smallholder farmers…

  16. Centrally managed unified shared virtual address space

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkes, John

    Systems, apparatuses, and methods for managing a unified shared virtual address space. A host may execute system software and manage a plurality of nodes coupled to the host. The host may send work tasks to the nodes, and for each node, the host may externally manage the node's view of the system's virtual address space. Each node may have a central processing unit (CPU) style memory management unit (MMU) with an internal translation lookaside buffer (TLB). In one embodiment, the host may be coupled to a given node via an input/output memory management unit (IOMMU) interface, where the IOMMU frontendmore » interface shares the TLB with the given node's MMU. In another embodiment, the host may control the given node's view of virtual address space via memory-mapped control registers.« less

  17. Potential for shared log transport services

    Treesearch

    Tim McDonald; Steve Taylor; Jorge Valenzuela

    2001-01-01

    A simulation model of a log transport logistics network was developed. The model could be structured to either share truck capacity among a group of loggers, or to assign a fixed number of trucks to individual loggers. Another variation of the model allowed the use of a staging yard to set out loaded trailers and deliver them to destinations using dedicated shuttle...

  18. Building Capacity for a Long-Term, in-Situ, National-Scale Phenology Monitoring Network: Successes, Challenges and Lessons Learned

    NASA Astrophysics Data System (ADS)

    Weltzin, J. F.; Browning, D. M.

    2014-12-01

    The USA National Phenology Network (USA-NPN; www.usanpn.org) is a national-scale science and monitoring initiative focused on phenology - the study of seasonal life-cycle events such as leafing, flowering, reproduction, and migration - as a tool to understand the response of biodiversity to environmental variation and change. USA-NPN provides a hierarchical, national monitoring framework that enables other organizations to leverage the capacity of the Network for their own applications - minimizing investment and duplication of effort - while promoting interoperability. Network participants can leverage: (1) Standardized monitoring protocols that have been broadly vetted, tested and published; (2) A centralized National Phenology Database (NPDb) for maintaining, archiving and replicating data, with standard metadata, terms-of-use, web-services, and documentation of QA/QC, plus tools for discovery, visualization and download of raw data and derived data products; and/or (3) A national in-situ, multi-taxa phenological monitoring system, Nature's Notebook, which enables participants to observe and record phenology of plants and animals - based on the protocols and information management system (IMS) described above - via either web or mobile applications. The protocols, NPDb and IMS, and Nature's Notebook represent a hierarchy of opportunities for involvement by a broad range of interested stakeholders, from individuals to agencies. For example, some organizations have adopted (e.g., the National Ecological Observatory Network or NEON) -- or are considering adopting (e.g., the Long-Term Agroecosystems Network or LTAR) -- the USA-NPN standardized protocols, but will develop their own database and IMS with web services to promote sharing of data with the NPDb. Other organizations (e.g., the Inventory and Monitoring Programs of the National Wildlife Refuge System and the National Park Service) have elected to use Nature's Notebook to support their phenological monitoring programs. We highlight the challenges and benefits of integrating phenology monitoring within existing and emerging national monitoring networks, and showcase opportunities that exist when standardized protocols are adopted and implemented to promote data interoperability and sharing.

  19. A medical home: value and implications of knowledge management.

    PubMed

    Orzano, A John; McInerney, Claire R; McDaniel, Reuben R; Meese, Abigail; Alajmi, Bibi; Mohr, Stewart M; Tallia, Alfred F

    2009-01-01

    Central to the "medical home" concept is the premise that the delivery of effective primary care requires a fundamental shift in relationships among practice members and between practice members and patients. Primary care practices can potentially increase their capacity to deliver effective care through knowledge management (KM), a process of sharing and making existing knowledge available or by developing new knowledge among practice members and patients. KM affects performance by influencing work relationships to enhance learning, decision making, and task execution. We extend our previous work to further characterize, describe, and contrast how primary care practices exhibit KM and explain why KM deserves attention in medical home redesign initiatives. Case studies were conducted, drawn from two higher and lower performing practices, which were purposely selected based on disease management, prevention, and productivity measures from an improvement trial. Observations of operations, clinical encounters, meetings, and interviews with office members and patients were transcribed and coded independently using a KM template developed from a previous secondary analysis. Face-to-face discussions resolved coding differences among research team members. Confirmation of findings was sought from practice participants. Practices manifested varying degrees of KM effectiveness through six interdependent processes and multiple overlapping tools. Social tools, such as face-to-face-communication for sharing and developing knowledge, were often more effective than were expensive technical tools such as an electronic medical record. Tool use was tailored for specific outcomes, interacted with each other, and leveraged by other organizational capacities. Practices with effective KM were more open to adopting and sustaining new ways of functioning, ways reflecting attributes of a medical home. Knowledge management differences occur within and between practices and can explain differences in performance. By relying more on social tools rather than costly, high-tech investment, KM leverages primary care's relationship-centered strength, facilitating practice redesign as a medical home.

  20. Enhancing the relevance of new scenarios for climate change impacts, adaptation and vulnerability research

    NASA Astrophysics Data System (ADS)

    van Ruijven, B. J.

    2013-12-01

    Over the past three decades, scenario analyses have occupied a central role in assessments of the potential impacts of climate change on natural and human systems at different scales during the 21st century. Here, we discuss the role and relevance of new scenarios using shared socioeconomic pathways (SSPs) and representative concentration pathways (RCPs) for climate change impacts, adaptation, and vulnerability (IAV) research. It first provides an overview of uses of social-environmental scenarios in IAV studies and identifies the main shortcomings of earlier such scenarios. Second, the paper elaborates on two aspects of new scenarios needing to be improved in order to enhance their usefulness for IAV studies: the ability to work coherently across spatial scales and adding indicators of importance to projections of vulnerability and adaptive capacity in addition to standard indicators of population and gross domestic product. This paper presents a research agenda to add income distribution, spatial population, human health projections, and governance indicators to the new scenarios.

  1. The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

    PubMed Central

    MELANDER, MARIA C.; JÜRGENSEN, HENRIK J.; MADSEN, DANIEL H.; ENGELHOLM, LARS H.; BEHRENDT, NIELS

    2015-01-01

    The collagen receptor uPARAP/Endo180, the product of the MRC2 gene, is a central component in the collagen turnover process governed by various mesenchymal cells. Through the endocytosis of collagen or large collagen fragments, this recycling receptor serves to direct basement membrane collagen as well as interstitial collagen to lysosomal degradation. This capacity, shared only with the mannose receptor from the same protein family, endows uPARAP/Endo180 with a critical role in development and homeostasis, as well as in pathological disruptions of the extracellular matrix structure. Important pathological functions of uPARAP/Endo180 have been identified in various cancers and in several fibrotic conditions. With a particular focus on matrix turnover in cancer, this review presents the necessary background for understanding the function of uPARAP/Endo180 at the molecular and cellular level, followed by an in-depth survey of the available knowledge of the expression and role of this receptor in various types of cancer and other degenerative diseases. PMID:26316068

  2. A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury

    PubMed Central

    Koch, Marta; Nicolas, Maya; Zschaetzsch, Marlen; de Geest, Natalie; Claeys, Annelies; Yan, Jiekun; Morgan, Matthew J.; Erfurth, Maria-Luise; Holt, Matthew; Schmucker, Dietmar; Hassan, Bassem A.

    2018-01-01

    Injury to the adult central nervous systems (CNS) can result in severe long-term disability because damaged CNS connections fail to regenerate after trauma. Identification of regulators that enhance the intrinsic growth capacity of severed axons is a first step to restore function. Here, we conducted a gain-of-function genetic screen in Drosophila to identify strong inducers of axonal growth after injury. We focus on a novel axis the Down Syndrome Cell Adhesion Molecule (Dscam1), the de-ubiquitinating enzyme Fat Facets (Faf)/Usp9x and the Jun N-Terminal Kinase (JNK) pathway transcription factor Kayak (Kay)/Fos. Genetic and biochemical analyses link these genes in a common signaling pathway whereby Faf stabilizes Dscam1 protein levels, by acting on the 3′-UTR of its mRNA, and Dscam1 acts upstream of the growth-promoting JNK signal. The mammalian homolog of Faf, Usp9x/FAM, shares both the regenerative and Dscam1 stabilizing activities, suggesting a conserved mechanism. PMID:29472843

  3. A Tamper-Resistant and Portable Healthcare Folder

    PubMed Central

    Anciaux, Nicolas; Berthelot, Morgane; Braconnier, Laurent; Bouganim, Luc; De la Blache, Martine; Gardarin, Georges; Kesmarszky, Philippe; Lartigue, Sophie; Navarre, Jean-François; Pucheral, Philippe; Vandewalle, Jean-Jacques; Zeitouni, Karine

    2008-01-01

    Electronic health record (EHR) projects have been launched in most developed countries to increase the quality of healthcare while decreasing its cost. The benefits provided by centralizing the healthcare information in database systems are unquestionable in terms of information quality, availability, and protection against failure. Yet, patients are reluctant to give to a distant server the control over highly sensitive data (e.g., data revealing a severe or shameful disease). This paper capitalizes on a new hardware portable device, associating the security of a smart card to the storage capacity of a USB key, to give back to the patient the control over his medical data. This paper shows how this device can complement a traditional EHR server to (1) protect and share highly sensitive data among trusted parties and (2) provide a seamless access to the data even in disconnected mode. The proposed architecture is experimented in the context of a medicosocial network providing medical care and social services at home for elderly people. PMID:18615200

  4. Uncharted terrain: preference construction at the end of life.

    PubMed

    White, Mary T

    2014-01-01

    Respect for patients' self-determination has long been considered central to efforts to improve end-of-life care, yet efforts to promote advance directives or engage patients in end-of-life discussions are often unsuccessful. In this article, I contend that this is because the shared decision-making approach typically used in healthcare assumes patients' capacity to make rational choices, which is not always possible in end-of-life decisions. Drawing on decision theory, behavioral psychology, and related studies of end-of-life care, I present a growing body of evidence that suggests the novelty, complexity, and uncertainty of end-of-life circumstances make rational and stable preferences difficult to establish. I argue that an effective decision-making approach for the terminally ill must recognize and respond to the unique characteristics of end-of-life choices, including their nonrational dimensions. I conclude with a description of an initiative that appears to do so, resulting in increased patients' satisfaction. Copyright 2014 The Journal of Clinical Ethics. All rights reserved.

  5. Single-molecule protein unfolding and translocation by an ATP-fueled proteolytic machine

    PubMed Central

    Aubin-Tam, Marie-Eve; Olivares, Adrian O.; Sauer, Robert T.; Baker, Tania A.; Lang, Matthew J.

    2011-01-01

    All cells employ ATP-powered proteases for protein-quality control and regulation. In the ClpXP protease, ClpX is a AAA+ machine that recognizes specific protein substrates, unfolds these molecules, and then translocates the denatured polypeptide through a central pore and into ClpP for degradation. Here, we use optical-trapping nanometry to probe the mechanics of enzymatic unfolding and translocation of single molecules of a multidomain substrate. Our experiments demonstrate the capacity of ClpXP and ClpX to perform mechanical work under load, reveal very fast and highly cooperative unfolding of individual substrate domains, suggest a translocation step size of 5–8 amino acids, and support a power-stroke model of denaturation in which successful enzyme-mediated unfolding of stable domains requires coincidence between mechanical pulling by the enzyme and a transient stochastic reduction in protein stability. We anticipate that single-molecule studies of the mechanical properties of other AAA+ proteolytic machines will reveal many shared features with ClpXP. PMID:21496645

  6. The Adoption of Shared Mobility in California and Its Relationship with Other Components of Travel Behavior

    DOT National Transportation Integrated Search

    2018-03-01

    Emerging technologies and shared mobility services are quickly changing transportation. The popularity of these services is particularly high among millennials and those living in the dense central parts of cities. Still, the reasons behind the adopt...

  7. Capacity-Building Programs Under the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR)

    EPA Pesticide Factsheets

    The United States signed the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR) in August 2004 with five Central American countries (Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua) and the Dominican Republic.

  8. Watershed Central: Harnessing a social media tool to organize local technical knowledge and find the right watershed resources for your watershed

    EPA Science Inventory

    Watershed Central was developed to be a bridge between sharing and searching for information relating to watershed issues. This is dependent upon active user support through additions and updates to the Watershed Central Wiki. Since the wiki is user driven, the content and applic...

  9. A benders decomposition approach to multiarea stochastic distributed utility planning

    NASA Astrophysics Data System (ADS)

    McCusker, Susan Ann

    Until recently, small, modular generation and storage options---distributed resources (DRs)---have been installed principally in areas too remote for economic power grid connection and sensitive applications requiring backup capacity. Recent regulatory changes and DR advances, however, have lead utilities to reconsider the role of DRs. To a utility facing distribution capacity bottlenecks or uncertain load growth, DRs can be particularly valuable since they can be dispersed throughout the system and constructed relatively quickly. DR value is determined by comparing its costs to avoided central generation expenses (i.e., marginal costs) and distribution investments. This requires a comprehensive central and local planning and production model, since central system marginal costs result from system interactions over space and time. This dissertation develops and applies an iterative generalized Benders decomposition approach to coordinate models for optimal DR evaluation. Three coordinated models exchange investment, net power demand, and avoided cost information to minimize overall expansion costs. Local investment and production decisions are made by a local mixed integer linear program. Central system investment decisions are made by a LP, and production costs are estimated by a stochastic multi-area production costing model with Kirchhoff's Voltage and Current Law constraints. The nested decomposition is a new and unique method for distributed utility planning that partitions the variables twice to separate local and central investment and production variables, and provides upper and lower bounds on expected expansion costs. Kirchhoff's Voltage Law imposes nonlinear, nonconvex constraints that preclude use of LP if transmission capacity is available in a looped transmission system. This dissertation develops KVL constraint approximations that permit the nested decomposition to consider new transmission resources, while maintaining linearity in the three individual models. These constraints are presented as a heuristic for the given examples; future research will investigate conditions for convergence. A ten-year multi-area example demonstrates the decomposition approach and suggests the ability of DRs and new transmission to modify capacity additions and production costs by changing demand and power flows. Results demonstrate that DR and new transmission options may lead to greater capacity additions, but resulting production cost savings more than offset extra capacity costs.

  10. Impact of auditory selective attention on verbal short-term memory and vocabulary development.

    PubMed

    Majerus, Steve; Heiligenstein, Lucie; Gautherot, Nathalie; Poncelet, Martine; Van der Linden, Martial

    2009-05-01

    This study investigated the role of auditory selective attention capacities as a possible mediator of the well-established association between verbal short-term memory (STM) and vocabulary development. A total of 47 6- and 7-year-olds were administered verbal immediate serial recall and auditory attention tasks. Both task types probed processing of item and serial order information because recent studies have shown this distinction to be critical when exploring relations between STM and lexical development. Multiple regression and variance partitioning analyses highlighted two variables as determinants of vocabulary development: (a) a serial order processing variable shared by STM order recall and a selective attention task for sequence information and (b) an attentional variable shared by selective attention measures targeting item or sequence information. The current study highlights the need for integrative STM models, accounting for conjoined influences of attentional capacities and serial order processing capacities on STM performance and the establishment of the lexical language network.

  11. Measuring the learning capacity of organisations: development and factor analysis of the Questionnaire for Learning Organizations.

    PubMed

    Oudejans, S C C; Schippers, G M; Schramade, M H; Koeter, M W J; van den Brink, W

    2011-04-01

    To investigate internal consistency and factor structure of a questionnaire measuring learning capacity based on Senge's theory of the five disciplines of a learning organisation: Personal Mastery, Mental Models, Shared Vision, Team Learning, and Systems Thinking. Cross-sectional study. Substance-abuse treatment centres (SATCs) in The Netherlands. A total of 293 SATC employees from outpatient and inpatient treatment departments, financial and human resources departments. Psychometric properties of the Questionnaire for Learning Organizations (QLO), including factor structure, internal consistency, and interscale correlations. A five-factor model representing the five disciplines of Senge showed good fit. The scales for Personal Mastery, Shared Vision and Team Learning had good internal consistency, but the scales for Systems Thinking and Mental Models had low internal consistency. The proposed five-factor structure was confirmed in the QLO, which makes it a promising instrument to assess learning capacity in teams. The Systems Thinking and the Mental Models scales have to be revised. Future research should be aimed at testing criterion and discriminatory validity.

  12. An Analysis of Implementation of the Defense Travel System at the Naval Postgraduate School

    DTIC Science & Technology

    2002-03-01

    processing called the Shared Services Office. The justification for this reorganization decision was to eliminate some inefficiency in the travel process...Table 2 shows the pros, cons, and issues surrounding the decision to create a Shared Services Office. Travel Manager was also modified to submit...service Location/space issues Expertise is centralized Travelers waiting for shared services concept to fail Coordinating the best order for

  13. Community Capacity Building and Sustainability: Outcomes of Community-Based Participatory Research

    PubMed Central

    Hacker, Karen; Tendulkar, Shalini A.; Rideout, Catlin; Bhuiya, Nazmim; Trinh-Shevrin, Chau; Savage, Clara P.; Grullon, Milagro; Strelnick, Hal; Leung, Carolyn; DiGirolamo, Ann

    2013-01-01

    Background For communities, the value of community-based participatory research (CBPR) is often manifested in the outcomes of increased capacity and sustainable adoption of evidence-based practices for social change. Educational opportunities that promote discourse between community and academic partners can help to advance CBPR and better define these outcomes. Objectives This paper describes a community–academic conference to develop shared definitions of community capacity building and sustainability related to CBPR and to identify obstacles and facilitators to both. Methods “Taking It to the Curbside: Engaging Communities to Create Sustainable Change for Health” was planned by five Clinical Translational Science Institutes and four community organizations. After a keynote presentation, breakout groups of community and academic members met to define community capacity building and sustainability, and to identify facilitators and barriers to achieving both. Groups were facilitated by researcher–community partner teams and conversations were recorded and transcribed. Qualitative analysis for thematic content was conducted by a subset of the planning committee. Results Important findings included learning that (1) the concepts of capacity and sustainability were considered interconnected; (2) partnership was perceived as both a facilitator and an outcome of CBPR; (3) sustainability was linked to “transfer of knowledge” from one generation to another within a community; and (4) capacity and sustainability were enhanced when goals were shared and health outcomes were achieved. Conclusions Community capacity building and sustainability are key outcomes of CBPR for communities. Co-learning opportunities that engage and mutually educate both community members and academics can be useful strategies for identifying meaningful strategies to achieve these outcomes. PMID:22982848

  14. Perceptions of organizational capacity to promote physical activity in Canada and ParticipACTION's influence five years after its relaunch: a qualitative study.

    PubMed

    Ramanathan, Subha; Faulkner, Guy; Berry, Tanya; Deshpande, Sameer; Latimer-Cheung, Amy E; Rhodes, Ryan E; Spence, John C; Tremblay, Mark S

    2018-04-01

    ParticipACTION is a Canadian physical activity communications and social marketing organization relaunched in 2007. The purpose of this study was to qualitatively investigate organizational capacity for physical activity promotion among Canadian organizations, and the influence of ParticipACTION on capacity five years after relaunch. Using a purposive sampling strategy, semi-structured telephone interviews were conducted with 44 key informants representing national, provincial, and local organizations with a mandate to promote physical activity. Interview data were analyzed using a thematic analytic approach. Organizational capacity in terms of partnerships and collaborations, and the general climate for physical activity promotion have improved since ParticipACTION's relaunch. Although financial resources reduced the ability of organizations to fulfil their mandates, internal factors such as skilled employees and sponsorships, and external factors such as technological improvements in communication and information sharing helped to offset this strain. There were mixed feelings on ParticipACTION's contribution to capacity. While ParticipACTION has brought more attention to inactivity, this was perceived as a complement to work already taking place. While some organizations perceived ParticipACTION's relaunch as competition to funding and access to popular media, others found it as an opportunity to co-brand social marketing campaigns, utilizing ParticipACTION's products and reputation. According to participants, organizational capacity to promote physical activity in Canada has increased since 2007 in subtle but important ways because of a strong climate for physical activity promotion, skilled employees, and information sharing technology. Organizational capacity changes were minimally attributed to ParticipACTION.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caldwell, M.M.; Eissenstat, D.M.; Richards, J.H.

    Two species of Agropyron grass differed strikingly in their capacity to compete for phosphate in soil interspaces shared with a common competitor, the sagebrush Artemisia tridentata. Of the total phosphorus-32 and -33 absorbed by Artemisia, 86% was from the interspace shared with Agropyron spicatum and only 14% from that shared with Agropyron desertorum. Actively absorbing mycorrhizal roots of Agropyron and Artemisia were present in both interspaces, where competition for the labeled phosphate occurred. The results have important implications about the way in which plants compete for resources below ground in both natural plant communities and agricultural intercropping systems.

  16. Erasmus+: Capacity Building in Higher Education. EU Support to Higher Education Institutions around the World

    ERIC Educational Resources Information Center

    Jongsma, Ard

    2016-01-01

    The aim of this brochure is to introduce those who are new to working with European Union funding, to the philosophy of Erasmus+ "capacity-building in higher education" projects. European Union experience of working on these types of projects will be shared. Examples of existing projects are scattered throughout the text to inspire you…

  17. Attention and Visuospatial Working Memory Share the Same Processing Resources

    PubMed Central

    Feng, Jing; Pratt, Jay; Spence, Ian

    2012-01-01

    Attention and visuospatial working memory (VWM) share very similar characteristics; both have the same upper bound of about four items in capacity and they recruit overlapping brain regions. We examined whether both attention and VWM share the same processing resources using a novel dual-task costs approach based on a load-varying dual-task technique. With sufficiently large loads on attention and VWM, considerable interference between the two processes was observed. A further load increase on either process produced reciprocal increases in interference on both processes, indicating that attention and VWM share common resources. More critically, comparison among four experiments on the reciprocal interference effects, as measured by the dual-task costs, demonstrates no significant contribution from additional processing other than the shared processes. These results support the notion that attention and VWM share the same processing resources. PMID:22529826

  18. Demographic patterns and trends in Central Ghana: baseline indicators from the Kintampo Health and Demographic Surveillance System

    PubMed Central

    Owusu-Agyei, Seth; Nettey, Obed Ernest A.; Zandoh, Charles; Sulemana, Abubakari; Adda, Robert; Amenga-Etego, Seeba; Mbacke, Cheikh

    2012-01-01

    Background The dearth of health and demographic data in sub-Saharan Africa from vital registration systems and its impact on effective planning for health and socio-economic development is widely documented. Health and Demographic Surveillance Systems have the capacity to address the dearth of quality data for policy making in resource-poor settings. Objective This article demonstrates the utility of the Kintampo Health and Demographic Surveillance System (KHDSS) by showing the patterns and trends of population change from 2005 to 2009 in the Kintampo North Municipality and Kintampo South districts of Ghana through data obtained from the KHDSS biannual update rounds. Design Basic demographic rates for fertility, mortality, and migration were computed by year. School enrolment was computed as a percentage in school by age and sex for 6–18 year-olds. Socio-economic status was derived by use of Principal Components Analysis on household assets. Results Over the period, an earlier fertility decline was reversed in 2009; mortality declined slightly for all age-groups, and a significant share of working-age population was lost through out-migration. Large minorities of children of school-going age are not in school. Socio-economic factors are shown to be important determinants of fertility and mortality. Conclusion Strengthening the capacity of HDSSs could offer added value to evidence-driven policymaking at local level. PMID:23273249

  19. Demographic patterns and trends in Central Ghana: baseline indicators from the Kintampo Health and Demographic Surveillance System.

    PubMed

    Owusu-Agyei, Seth; Nettey, Obed Ernest A; Zandoh, Charles; Sulemana, Abubakari; Adda, Robert; Amenga-Etego, Seeba; Mbacke, Cheikh

    2012-12-20

    The dearth of health and demographic data in sub-Saharan Africa from vital registration systems and its impact on effective planning for health and socio-economic development is widely documented. Health and Demographic Surveillance Systems have the capacity to address the dearth of quality data for policy making in resource-poor settings. This article demonstrates the utility of the Kintampo Health and Demographic Surveillance System (KHDSS) by showing the patterns and trends of population change from 2005 to 2009 in the Kintampo North Municipality and Kintampo South districts of Ghana through data obtained from the KHDSS biannual update rounds. Basic demographic rates for fertility, mortality, and migration were computed by year. School enrolment was computed as a percentage in school by age and sex for 6-18 year-olds. Socio-economic status was derived by use of Principal Components Analysis on household assets. Over the period, an earlier fertility decline was reversed in 2009; mortality declined slightly for all age-groups, and a significant share of working-age population was lost through out-migration. Large minorities of children of school-going age are not in school. Socio-economic factors are shown to be important determinants of fertility and mortality. Strengthening the capacity of HDSSs could offer added value to evidence-driven policymaking at local level.

  20. The Magical Mystery Four: How is Working Memory Capacity Limited, and Why?

    PubMed Central

    Cowan, Nelson

    2009-01-01

    Working memory storage capacity is important because cognitive tasks can be completed only with sufficient ability to hold information as it is processed. The ability to repeat information depends on task demands but can be distinguished from a more constant, underlying mechanism: a central memory store limited to 3 to 5 meaningful items in young adults. I will discuss why this central limit is important, how it can be observed, how it differs among individuals, and why it may occur. PMID:20445769

  1. 75 FR 55317 - Central Vermont Public Service Corporation; Notice of Application for Amendment of License and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... approval to replace the existing Unit 1 turbine, with a hydraulic capacity of 162 cfs and a nameplate capacity of 1,100 kW, with a new turbine unit having a hydraulic capacity of 177 cfs and a nameplate... 1,900 kW to 2,251 kW, and increase total project hydraulic capacity from 254 cfs to 269 cfs. l. A...

  2. Working memory capacity and the functional connectome - insights from resting-state fMRI and voxelwise centrality mapping.

    PubMed

    Markett, Sebastian; Reuter, Martin; Heeren, Behrend; Lachmann, Bernd; Weber, Bernd; Montag, Christian

    2018-02-01

    The functional connectome represents a comprehensive network map of functional connectivity throughout the human brain. To date, the relationship between the organization of functional connectivity and cognitive performance measures is still poorly understood. In the present study we use resting-state functional magnetic resonance imaging (fMRI) data to explore the link between the functional connectome and working memory capacity in an individual differences design. Working memory capacity, which refers to the maximum amount of context information that an individual can retain in the absence of external stimulation, was assessed outside the MRI scanner and estimated based on behavioral data from a change detection task. Resting-state time series were analyzed by means of voxelwise degree and eigenvector centrality mapping, which are data-driven network analytic approaches for the characterization of functional connectivity. We found working memory capacity to be inversely correlated with both centrality in the right intraparietal sulcus. Exploratory analyses revealed that this relationship was putatively driven by an increase in negative connectivity strength of the structure. This resting-state connectivity finding fits previous task based activation studies that have shown that this area responds to manipulations of working memory load.

  3. Super Kitchen Centralizes Food Service

    ERIC Educational Resources Information Center

    Modern Schools, 1975

    1975-01-01

    To centralize food service within the entire Pittsburgh school district, a 90,000-square-foot food service preparation building contains cranes and monorails to move 500-pound capacity vats throughout the kitchen. (Author/MLF)

  4. KENNEDY SPACE CENTER, FLA. - - U.S. Representative Ric Keller (left) listens intently to a presentation proposing the use of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. NASA and Florida officials toured the research park as well. Central Florida leaders are proposing the research park as the site for the center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - - U.S. Representative Ric Keller (left) listens intently to a presentation proposing the use of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. NASA and Florida officials toured the research park as well. Central Florida leaders are proposing the research park as the site for the center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  5. Levels of Social Sharing and Clinical Implications for Severe Social Withdrawal in Patients with Personality Disorders.

    PubMed

    Colle, Livia; Pellecchia, Giovanni; Moroni, Fabio; Carcione, Antonino; Nicolò, Giuseppe; Semerari, Antonio; Procacci, Michele

    2017-01-01

    Social sharing capacities have attracted attention from a number of fields of social cognition and have been variously defined and analyzed in numerous studies. Social sharing consists in the subjective awareness that aspects of the self's experience are held in common with other individuals. The definition of social sharing must take a variety of elements into consideration: the motivational element, the contents of the social sharing experience, the emotional responses it evokes, the behavioral outcomes, and finally, the circumstances and the skills which enable social sharing. The primary objective of this study is to explore some of the diverse forms of human social sharing and to classify them according to levels of complexity. We identify four different types of social sharing, categorized according to the nature of the content being shared and the complexity of the mindreading skills required. The second objective of this study is to consider possible applications of this graded model of social sharing experience in clinical settings. Specifically, this model may support the development of graded, focused clinical interventions for patients with personality disorders characterized by severe social withdrawal.

  6. The Shared Bibliographic Input Network (SBIN): A Summary of the Experiment.

    ERIC Educational Resources Information Center

    Cotter, Gladys A.

    As part of its mission to provide centralized services for the acquisition, storage, retrieval, and dissemination of scientific and technical information (STI) to support Department of Defense (DoD) research, development, and engineering studies programs, the Defense Technical Information Center (DTIC) sponsors the Shared Bibliographic Input…

  7. Reconnecting: A Phenomenological Study of Transition within a Shared Model of Academic Advising

    ERIC Educational Resources Information Center

    Barker, Shane; Mamiseishvili, Ketevan

    2014-01-01

    This study explored students' experiences of transition from centralized, professional advising to decentralized, faculty-based advising within a shared advising model at a public research university. Data were collected via focus groups and interviews from 17 participants and examined using phenomenological analysis. Four fundamental themes were…

  8. Learning to Share

    ERIC Educational Resources Information Center

    Raths, David

    2010-01-01

    In the tug-of-war between researchers and IT for supercomputing resources, a centralized approach can help both sides get more bang for their buck. As 2010 began, the University of Washington was preparing to launch its first shared high-performance computing cluster, a 1,500-node system called Hyak, dedicated to research activities. Like other…

  9. Experience Facilitates the Emergence of Sharing Behavior among 7.5-Month-Old Infants

    ERIC Educational Resources Information Center

    Xu, Jing; Saether, Lucie; Sommerville, Jessica A.

    2016-01-01

    Given the centrality of prosociality in everyday social functioning, understanding the factors and mechanisms underlying the origins of prosocial development is of critical importance. This experiment investigated whether experience with reciprocal object exchanges can drive the developmental onset of sharing behavior. Seven-month-old infants took…

  10. 12 CFR 725.7 - Special share accounts in federally chartered agent members.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Special share accounts in federally chartered agent members. 725.7 Section 725.7 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS NATIONAL CREDIT UNION ADMINISTRATION CENTRAL LIQUIDITY FACILITY § 725.7 Special...

  11. Hybrid lithium-ion capacitor with LiFePO4/AC composite cathode - Long term cycle life study, rate effect and charge sharing analysis

    NASA Astrophysics Data System (ADS)

    Shellikeri, A.; Yturriaga, S.; Zheng, J. S.; Cao, W.; Hagen, M.; Read, J. A.; Jow, T. R.; Zheng, J. P.

    2018-07-01

    Energy storage devices, which can combine the advantages of lithium-ion battery with that of electric double layer capacitor, are of prime interest. Recently, composite cathodes, which combine a battery material with capacitor material, have shown promise in enhancing life cycle and energy/power performances. Lithium-ion capacitor (LIC), with unique charge storage mechanism of combining a pre-lithiated battery anode with a capacitor cathode, is one such device which has the potential to synergistically incorporate the composite cathode to enhance capacity and cycle life. We report here a hybrid LIC consisting of a lithium iron phosphate (LiFePO4-LFP)/Activated Carbon composite cathode in combination with a hard carbon anode, by integrating the cycle life and capacity enhancing strategies of a dry method of electrode fabrication, anode pre-lithiation and a 3:1 anode to cathode capacity ratio, demonstrating a long cycle life, while elaborating on the charge sharing between the faradaic and non-faradaic mechanism in the battery and capacitor materials, respectively in the composite cathode. An excellent cell capacity retention of 94% (1000 cycles at 1C) and 92% (100,000 cycles at 60C) were demonstrated, while retaining 78% (over 6000 cycles at 2.7C) and 67% (over 70,000 cycles at 43C) of the LFP capacity in the composite cathode.

  12. Effects of massive wind power integration on short-term water resource management in central Chile - a grid-wide study

    NASA Astrophysics Data System (ADS)

    Haas, J.; Olivares, M. A.; Palma, R.

    2013-12-01

    In central Chile, water from reservoirs and streams is mainly used for irrigation and power generation. Hydropower reservoirs operation is particularly challenging because: i) decisions at each plant impact the entire power system, and ii) the existence of large storage capacity implies inter-temporal ties. An Independent System Operator (ISO) decides the grid-wide optimal allocation of water for power generation, under irrigation-related constraints. To account for the long-term opportunity cost of water, a future cost function is determined and used in the short term planning. As population growth and green policies demand increasing levels of renewable energy in power systems, deployment of wind farms and solar plants is rising quickly. However, their power output is highly fluctuating on short time scales, affecting the operation of power plants, particularly those fast responding units as hydropower reservoirs. This study addresses these indirect consequences of massive introduction of green energy sources on reservoir operations. Short-term reservoir operation, under different wind penetration scenarios, is simulated using a replica of Chile's ISO's scheduling optimization tools. Furthermore, an ongoing study is exploring the potential to augment the capacity the existing hydro-power plants to better cope with the balancing needs due to a higher wind power share in the system. As reservoir releases determine to a great extent flows at downstream locations, hourly time series of turbined flows for 24-hour periods were computed for selected combinations between new wind farms and increased capacity of existing hydropower plants. These time series are compiled into subdaily hydrologic alteration (SDHA) indexes (Zimmerman et al, 2010). The resulting sample of indexes is then analyzed using duration curves. Results show a clear increase in the SDHA for every reservoir of the system as more fluctuating renewables are integrated into the system. High-fluctuation events become more frequent. While the main load-following reservoirs are very susceptible to even small levels of additional wind power, the remaining withstand greater amounts before producing a significant SDHA. The additional effect of augmented installed capacity of existing hydropower plants on the SDHA is modest. The increase in SDHA calls for alternative operational constraints beyond the current practice based exclusively on minimum instream flows. Previous research by this group has shown the potential of maximum ramping rates constraints to efficiently achieve improvement in the SDHA. This alternative is being studied as part of a project currently in progress. This may contribute to make hydropower projects more socially acceptable and environmentally sound.

  13. Metadata based management and sharing of distributed biomedical data

    PubMed Central

    Vergara-Niedermayr, Cristobal; Liu, Peiya

    2014-01-01

    Biomedical research data sharing is becoming increasingly important for researchers to reuse experiments, pool expertise and validate approaches. However, there are many hurdles for data sharing, including the unwillingness to share, lack of flexible data model for providing context information, difficulty to share syntactically and semantically consistent data across distributed institutions, and high cost to provide tools to share the data. SciPort is a web-based collaborative biomedical data sharing platform to support data sharing across distributed organisations. SciPort provides a generic metadata model to flexibly customise and organise the data. To enable convenient data sharing, SciPort provides a central server based data sharing architecture with a one-click data sharing from a local server. To enable consistency, SciPort provides collaborative distributed schema management across distributed sites. To enable semantic consistency, SciPort provides semantic tagging through controlled vocabularies. SciPort is lightweight and can be easily deployed for building data sharing communities. PMID:24834105

  14. Research into display sharing techniques for distributed computing environments

    NASA Technical Reports Server (NTRS)

    Hugg, Steven B.; Fitzgerald, Paul F., Jr.; Rosson, Nina Y.; Johns, Stephen R.

    1990-01-01

    The X-based Display Sharing solution for distributed computing environments is described. The Display Sharing prototype includes the base functionality for telecast and display copy requirements. Since the prototype implementation is modular and the system design provided flexibility for the Mission Control Center Upgrade (MCCU) operational consideration, the prototype implementation can be the baseline for a production Display Sharing implementation. To facilitate the process the following discussions are presented: Theory of operation; System of architecture; Using the prototype; Software description; Research tools; Prototype evaluation; and Outstanding issues. The prototype is based on the concept of a dedicated central host performing the majority of the Display Sharing processing, allowing minimal impact on each individual workstation. Each workstation participating in Display Sharing hosts programs to facilitate the user's access to Display Sharing as host machine.

  15. Patient-controlled sharing of medical imaging data across unaffiliated healthcare organizations

    PubMed Central

    Ahn, David K; Unde, Bhagyashree; Gage, H Donald; Carr, J Jeffrey

    2013-01-01

    Background Current image sharing is carried out by manual transportation of CDs by patients or organization-coordinated sharing networks. The former places a significant burden on patients and providers. The latter faces challenges to patient privacy. Objective To allow healthcare providers efficient access to medical imaging data acquired at other unaffiliated healthcare facilities while ensuring strong protection of patient privacy and minimizing burden on patients, providers, and the information technology infrastructure. Methods An image sharing framework is described that involves patients as an integral part of, and with full control of, the image sharing process. Central to this framework is the Patient Controlled Access-key REgistry (PCARE) which manages the access keys issued by image source facilities. When digitally signed by patients, the access keys are used by any requesting facility to retrieve the associated imaging data from the source facility. A centralized patient portal, called a PCARE patient control portal, allows patients to manage all the access keys in PCARE. Results A prototype of the PCARE framework has been developed by extending open-source technology. The results for feasibility, performance, and user assessments are encouraging and demonstrate the benefits of patient-controlled image sharing. Discussion The PCARE framework is effective in many important clinical cases of image sharing and can be used to integrate organization-coordinated sharing networks. The same framework can also be used to realize a longitudinal virtual electronic health record. Conclusion The PCARE framework allows prior imaging data to be shared among unaffiliated healthcare facilities while protecting patient privacy with minimal burden on patients, providers, and infrastructure. A prototype has been implemented to demonstrate the feasibility and benefits of this approach. PMID:22886546

  16. Attention capacity in European adolescents: role of different health-related factors. The HELENA study.

    PubMed

    Esteban-Cornejo, Irene; Cadenas-Sanchez, Cristina; Vanhelst, Jérémy; Michels, Nathalie; Lambrinou, Christina-Paulina; González-Gross, Marcela; Widhalm, Kurt; Kersting, Mathilde; de la O Puerta, Alejandro; Kafatos, Anthony; Moreno, Luis A; Ortega, Francisco B

    2017-10-01

    We compared the level of attention capacity between adolescents from the center and south of Europe. The study included 627 European adolescents (54% girls), aged 12.5-17.5 years, who participated in the HELENA Study. The d2 Test of Attention was administered to assess attention capacity. The main results showed that adolescents from the south of Europe had significantly higher score in attention capacity compared with adolescents from central Europe (score + 8.1; 95%CI, 2.44-13.61) after adjustment for age, sex, socioeconomic indicators, body mass index, cardiorespiratory fitness and diet quality index (p = 0.012). Adolescents from the south of Europe had higher levels of attention capacity than their counterparts from central Europe independently of sociodemographic and health-related factors. These differences should be taken into account by educational institutions when promoting new approaches for putting into the practice student's capacities. What is Known? • Attention is a crucial capacity during adolescence. • Several health-related factors (i.e., physical activity, fitness or fatness) may influence attention capacity in adolescents. What is New? • Adolescents from the south of Europe had higher levels of attention capacity than their counterparts from the center, after accounting for socioeconomic factors, fitness, fatness and quality of diet. • These differences should be taken into account by educational institutions when promoting new approaches for putting into the practice student's capacities.

  17. Using secure web services to visualize poison center data for nationwide biosurveillance: a case study.

    PubMed

    Savel, Thomas G; Bronstein, Alvin; Duck, William; Rhodes, M Barry; Lee, Brian; Stinn, John; Worthen, Katherine

    2010-01-01

    Real-time surveillance systems are valuable for timely response to public health emergencies. It has been challenging to leverage existing surveillance systems in state and local communities, and, using a centralized architecture, add new data sources and analytical capacity. Because this centralized model has proven to be difficult to maintain and enhance, the US Centers for Disease Control and Prevention (CDC) has been examining the ability to use a federated model based on secure web services architecture, with data stewardship remaining with the data provider. As a case study for this approach, the American Association of Poison Control Centers and the CDC extended an existing data warehouse via a secure web service, and shared aggregate clinical effects and case counts data by geographic region and time period. To visualize these data, CDC developed a web browser-based interface, Quicksilver, which leveraged the Google Maps API and Flot, a javascript plotting library. Two iterations of the NPDS web service were completed in 12 weeks. The visualization client, Quicksilver, was developed in four months. This implementation of web services combined with a visualization client represents incremental positive progress in transitioning national data sources like BioSense and NPDS to a federated data exchange model. Quicksilver effectively demonstrates how the use of secure web services in conjunction with a lightweight, rapidly deployed visualization client can easily integrate isolated data sources for biosurveillance.

  18. Organisational adaptation in an activist network: social networks, leadership, and change in al-Muhajiroun.

    PubMed

    Kenney, Michael; Horgan, John; Horne, Cale; Vining, Peter; Carley, Kathleen M; Bigrigg, Michael W; Bloom, Mia; Braddock, Kurt

    2013-09-01

    Social networks are said to facilitate learning and adaptation by providing the connections through which network nodes (or agents) share information and experience. Yet, our understanding of how this process unfolds in real-world networks remains underdeveloped. This paper explores this gap through a case study of al-Muhajiroun, an activist network that continues to call for the establishment of an Islamic state in Britain despite being formally outlawed by British authorities. Drawing on organisation theory and social network analysis, we formulate three hypotheses regarding the learning capacity and social network properties of al-Muhajiroun (AM) and its successor groups. We then test these hypotheses using mixed methods. Our methods combine quantitative analysis of three agent-based networks in AM measured for structural properties that facilitate learning, including connectedness, betweenness centrality and eigenvector centrality, with qualitative analysis of interviews with AM activists focusing organisational adaptation and learning. The results of these analyses confirm that al-Muhajiroun activists respond to government pressure by changing their operations, including creating new platforms under different names and adjusting leadership roles among movement veterans to accommodate their spiritual leader's unwelcome exodus to Lebanon. Simple as they are effective, these adaptations have allowed al-Muhajiroun and its successor groups to continue their activism in an increasingly hostile environment. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  19. Prediction-based dynamic load-sharing heuristics

    NASA Technical Reports Server (NTRS)

    Goswami, Kumar K.; Devarakonda, Murthy; Iyer, Ravishankar K.

    1993-01-01

    The authors present dynamic load-sharing heuristics that use predicted resource requirements of processes to manage workloads in a distributed system. A previously developed statistical pattern-recognition method is employed for resource prediction. While nonprediction-based heuristics depend on a rapidly changing system status, the new heuristics depend on slowly changing program resource usage patterns. Furthermore, prediction-based heuristics can be more effective since they use future requirements rather than just the current system state. Four prediction-based heuristics, two centralized and two distributed, are presented. Using trace driven simulations, they are compared against random scheduling and two effective nonprediction based heuristics. Results show that the prediction-based centralized heuristics achieve up to 30 percent better response times than the nonprediction centralized heuristic, and that the prediction-based distributed heuristics achieve up to 50 percent improvements relative to their nonprediction counterpart.

  20. Perceptions of organizational capacity to promote physical activity in Canada and ParticipACTION’s influence five years after its relaunch: a qualitative study

    PubMed Central

    Subha, Ramanathan; Guy, Faulkner; Tanya, Berry; Sameer, Deshpande; Amy E., Latimer-Cheung; Ryan E., Rhodes; John C., Spence; Mark S., Tremblay

    2018-01-01

    Abstract Introduction: ParticipACTION is a Canadian physical activity communications and social marketing organization relaunched in 2007. The purpose of this study was to qualitatively investigate organizational capacity for physical activity promotion among Canadian organizations, and the influence of ParticipACTION on capacity five years after relaunch. Methods: Using a purposive sampling strategy, semi-structured telephone interviews were conducted with 44 key informants representing national, provincial, and local organizations with a mandate to promote physical activity. Interview data were analyzed using a thematic analytic approach. Results: Organizational capacity in terms of partnerships and collaborations, and the general climate for physical activity promotion have improved since ParticipACTION’s relaunch. Although financial resources reduced the ability of organizations to fulfil their mandates, internal factors such as skilled employees and sponsorships, and external factors such as technological improvements in communication and information sharing helped to offset this strain. There were mixed feelings on ParticipACTION’s contribution to capacity. While ParticipACTION has brought more attention to inactivity, this was perceived as a complement to work already taking place. While some organizations perceived ParticipACTION’s relaunch as competition to funding and access to popular media, others found it as an opportunity to co-brand social marketing campaigns, utilizing ParticipACTION’s products and reputation. Conclusion: According to participants, organizational capacity to promote physical activity in Canada has increased since 2007 in subtle but important ways because of a strong climate for physical activity promotion, skilled employees, and information sharing technology. Organizational capacity changes were minimally attributed to ParticipACTION. PMID:29671966

  1. 16 CFR Appendix I to Part 305 - Heating Performance and Cost for Central Air Conditioners

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... for Central Air Conditioners Manufacturer's rated heating capacity (Btu's/hr.) Range of HSPF's Low... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Heating Performance and Cost for Central Air Conditioners I Appendix I to Part 305 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC...

  2. From Policy to Practice: The Implementation and Negotiation of Technologies in Everyday Child Welfare

    ERIC Educational Resources Information Center

    Peckover, Sue; Hall, Christopher; White, Sue

    2009-01-01

    A central element of the Every Child Matters reforms in England are measures which aim at improving information sharing. Amongst these are the children's database and the Common Assessment Framework, both representing technological solutions to long-standing concerns about information sharing in child welfare. This article reports some findings…

  3. An Evaluation of a Shared Leadership Training Program

    ERIC Educational Resources Information Center

    Allen, Lavonda Ann

    2010-01-01

    The purpose of the quantitative quasi-experimental equivalent time series study was to evaluate the effectiveness of a work based shared leadership training program in a less than 200 bed hospital in rural, south-central United States. Nursing shortages and the current emphasis on quality are factors that make recruitment and retention of nurses…

  4. Intergovernmental Information Highways for Local Police Organizations: A Case Study

    ERIC Educational Resources Information Center

    Vidal, Denise Helena

    2013-01-01

    A lack of communication, information sharing, and a centralized and unified intelligence repository to gather, maintain, and analyze intelligence information before the September 11, 2001 (9/11) terrorist attacks limited the ability of U.S. law enforcement to share intelligence. The problem addressed in this case study was the lack of multiagency…

  5. Information-Sharing Application Standards for Integrated Government Systems

    DTIC Science & Technology

    2010-12-01

    23 4. Federated Search and Role-Based Data Access ................ 24 G. LESSONS FROM HSIN...4. Federated Search and Role-Based Data Access One of the original purposes of HSIN was to facilitate information sharing...recent search paradigm, Federated Search , allows separate systems to feed external data requests without the need for a huge centralized database

  6. Usage Analysis of a Shared Care Planning System

    PubMed Central

    Warren, Jim; Gu, Yulong; Humphrey, Gayl

    2012-01-01

    We examined the content of electronically mediated communications in a trial of shared care planning (SCP) for long-term condition management. Software supports SCP by sharing patient records and care plans among members of the multidisciplinary care team (with patient access). Our analysis focuses on a three-month period with 73 enrolled patients, 149 provider-assigned tasks, 64 clinical notes and 48 care plans with 162 plan elements. Results show that content of notes entries is often related to task assignment and that nurses are the most active users. Directions for refinement of the SCP technology are indicated, including better integration of notes, tasks and care team notifications, as well as the central role of nurses for design use cases. Broader issues are raised about workforce roles and responsibilities for SCP, integrating patient-provider and provider-provider communications, and the centrality of care plans as the key entity in mediation of the care team. PMID:23304370

  7. Adoption of a Nationwide Shared Medical Record in France: Lessons Learnt after 5 Years of Deployment

    PubMed Central

    Séroussi, Brigitte; Bouaud, Jacques

    2016-01-01

    Information sharing among health practitioners, either for coordinated or unscheduled care, is necessary to guarantee care quality and patient safety. In most countries, nationwide programs have provided tools to support information sharing, from centralized care records to health information exchange between electronic health records (EHRs). The French personal medical record (DMP) is a centralized patient-controlled record, created according to the opt-in consent model. It contains the documents health practitioners voluntarily push into the DMP from their EHRs. Five years after the launching of the program in December 2010, there were nearly 570,000 DMPs covering only 1.5% of the target population in December 2015. Reasons for this poor level of adoption are discussed in the perspective of other countries’ initiatives. The new French governmental strategy for the DMP deployment in 2016 is outlined, with the implementation of measures similar to the US Meaningful Use. PMID:28269907

  8. Use of a Nationwide Personally Controlled Electronic Health Record by Healthcare Professionals and Patients: A Case Study with the French DMP.

    PubMed

    Seroussi, Brigitte; Bouaud, Jacques

    2017-01-01

    If the wide adoption of electronic health records (EHRs) is necessary to address health information sharing and care coordination issues, it is not sufficient. In order to address health information sharing, some countries, among which, France, have implemented a centralized framework with "new" nationwide care records. The French DMP is a centralized, nationally shared, electronic medical record, created according to the opt-in model. More than five years after the launching of the DMP project, DMPs have been created for 1.5% of the target population, which demonstrates the poor adoption of the tool by healthcare professionals. Among the 583,997 existing DMPs in June 2016, 41% were empty, and 24% of non-empty DMPs were actually accessed. If these "active" DMPs were equally accessed by both healthcare professionals and patients, patients accessed DMP documents four times more than healthcare professionals.

  9. Integration of land-sharing and land-sparing conservation strategies through regional networking: the Mesoamerican Biological Corridor as a lifeline for carnivores in El Salvador.

    PubMed

    Crespin, Silvio J; García-Villalta, Jorge E

    2014-10-01

    Nations with little remaining natural habitat and small extent are challenged when trying to achieve biodiversity targets. We show that the Central American nation of El Salvador cannot viably sustain populations of 87 % of its extant carnivores, especially in the case of large-bodied species with low population densities. Current land-sparing strategies will not suffice; therefore we propose that land-sharing strategies be implemented in tandem with protected areas to expand current conservation efforts via new regional networks. In Central America such a network can be established by linking international protected area systems in a way that implements the existing vision for the Mesoamerican Biological Corridor. Specifically, we propose a re-envisioning of the Mesoamerican Biological Corridor in which land-sharing practices are adopted throughout the agricultural matrix while ensuring formal protection of the remaining natural habitat. Such an integration of land-sparing and land-sharing could result in the creation of an effective network of protected areas, thereby increasing the probability of safeguarding species with populations that overlap national borders.

  10. Annotating Atomic Components of Papers in Digital Libraries: The Semantic and Social Web Heading towards a Living Document Supporting eSciences

    NASA Astrophysics Data System (ADS)

    García Castro, Alexander; García-Castro, Leyla Jael; Labarga, Alberto; Giraldo, Olga; Montaña, César; O'Neil, Kieran; Bateman, John A.

    Rather than a document that is being constantly re-written as in the wiki approach, the Living Document (LD) is one that acts as a document router, operating by means of structured and organized social tagging and existing ontologies. It offers an environment where users can manage papers and related information, share their knowledge with their peers and discover hidden associations among the shared knowledge. The LD builds upon both the Semantic Web, which values the integration of well-structured data, and the Social Web, which aims to facilitate interaction amongst people by means of user-generated content. In this vein, the LD is similar to a social networking system, with users as central nodes in the network, with the difference that interaction is focused on papers rather than people. Papers, with their ability to represent research interests, expertise, affiliations, and links to web based tools and databanks, represent a central axis for interaction amongst users. To begin to show the potential of this vision, we have implemented a novel web prototype that enables researchers to accomplish three activities central to the Semantic Web vision: organizing, sharing and discovering. Availability: http://www.scientifik.info/

  11. Values of decentralized systems that avoid investments in idle capacity within the wastewater sector: a theoretical justification.

    PubMed

    Wang, Sheng

    2014-04-01

    In this work, the values of decentralized (onsite) systems that avoid investments in idle capacity within wastewater plans are quantitatively justified using the specific net present value (SNPV) approach. SNPV is a currently proposed criterion in environmental engineering economics that is defined as the net present value of the cost per unit of service or per population equivalent (PE). The SNPV approach was reintroduced with bugs fixed and then applied to the economic analysis of the capital and operating costs of one-stage completed central plants, stage-expanded central plants, and decentralized treatment facilities. The results show that under a demand growth scenario, the central plant will inevitably reach idle capacity, which can be reduced by a staged expansion. However, the staged expansion plan will lose the economies of scale and, hence, is only viable under projections of a low or moderate price inflation rate or high demand growth rate. Onsite treatment systems can theoretically achieve 100% utilization. Assuming that the capital costs per PE of the onsite and central systems are equal, the former is economically favorable in most cases of price inflation as a result of its cost saving on idle capacity. Onsite treatment systems can be viable even though their capital expenditures per PE are higher than that of a comparable centralized option as to a capital investment. This finding suggests wide opening of onsite technology choices. Use of the SNPV showed that average operating expenses of centralized plants decrease as demand growth rates increase as a benefit of economies of scale, whereas those of onsite treatment systems depend only on price inflation. Semi-decentralized systems feature both the financial advantage of the onsite system (capital investment) and the superiority of centralized systems (operation and maintenance); thus, it is worth consideration. The results of this study illustrate not only the value of decentralized systems but also the value of the SNPV approach in the planning of wastewater services, especially in areas undergoing high demand growth. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Moving towards shared decision making in the physician-patient encounter in France: State of the art and future prospects.

    PubMed

    Moumjid, Nora; Carretier, Julien; Marsico, Giovanna; Blot, François; Durif-Bruckert, Christine; Chauvin, Franck

    2017-06-01

    In this paper we present the evolution of shared decision making since the mid-nineties in terms of legislation, official statements and guidelines. We outline the goals and declarations of the French Ministry of Health and the French National Authority for Health, for whom informing patients and shared decision-making are central concerns. Finally, we discuss research projects and clinical initiatives in shared decision-making in France and provide a general overview of progress and barriers to progress. Copyright © 2017. Published by Elsevier GmbH.

  13. Fellowship Connects Principal Learning to Student Achievement: How an External Benefactor, a Research University, and an Urban School District Build Capacity for Problem Solving

    ERIC Educational Resources Information Center

    Dunbar, Krista; Monson, Robert J.

    2011-01-01

    Much has been written about the disconnect between education research produced in graduate schools of education and the practice of school leaders. In this article, the authors share one story of an external partnership that promotes the development of a principal's capacity for complex problem solving and the early research that suggests this…

  14. Steganography on multiple MP3 files using spread spectrum and Shamir's secret sharing

    NASA Astrophysics Data System (ADS)

    Yoeseph, N. M.; Purnomo, F. A.; Riasti, B. K.; Safiie, M. A.; Hidayat, T. N.

    2016-11-01

    The purpose of steganography is how to hide data into another media. In order to increase security of data, steganography technique is often combined with cryptography. The weakness of this combination technique is the data was centralized. Therefore, a steganography technique is develop by using combination of spread spectrum and secret sharing technique. In steganography with secret sharing, shares of data is created and hidden in several medium. Medium used to concealed shares were MP3 files. Hiding technique used was Spread Spectrum. Secret sharing scheme used was Shamir's Secret Sharing. The result showed that steganography with spread spectrum combined with Shamir's Secret Share using MP3 files as medium produce a technique that could hid data into several cover. To extract and reconstruct the data hidden in stego object, it is needed the amount of stego object which more or equal to its threshold. Furthermore, stego objects were imperceptible and robust.

  15. The conduct and process of mental capacity assessments in home health care settings.

    PubMed

    Cliff, Charlotte; McGraw, Caroline

    2016-11-02

    The assessment of capacity to consent to treatment is key to shared practitioner-patient decision-making. It is the responsibility of the person closest to the decision being made to carry out the assessment. The aim was to examine the factors that influence mental capacity assessments in home health care settings and identify the facilitators and inhibitors to the conduct and process of assessments as perceived and experienced by non-medical health practitioners providing generalist community services. Semi-structured interviews with a purposive sample of community nurses, community physiotherapists and community occupational therapists in one NHS Trust in London. Data were analysed thematically. The main themes were issues relating to: intrinsic patient factors and behaviours; recognising, managing and utilising the influence of the family; practitioner motivation and competence; working together as a team to optimise shared decision making, and; the importance of place. While some issues appear germane to both hospital and home health care settings, others are unique to - or manifest very differently in - home health care settings. The findings suggest that the influence of family members, long-term practitioner-patient relationships and physical distance from co-workers make the conduct and process of mental capacity assessments in home health care settings an inherently complex endeavour.

  16. Supporting shared decision making beyond consumer-prescriber interactions: Initial development of the CommonGround fidelity scale

    PubMed Central

    Fukui, Sadaaki; Salyers, Michelle P.; Rapp, Charlie; Goscha, Rick; Young, Leslie; Mabry, Ally

    2015-01-01

    Shared decision-making has become a central tenet of recovery-oriented, person-centered mental health care, yet the practice is not always transferred to the routine psychiatric visit. Supporting the practice at the system level, beyond the interactions of consumers and medication prescribers, is needed for successful adoption of shared decision-making. CommonGround is a systemic approach, intended to be part of a larger integration of shared decision-making tools and practices at the system level. We discuss the organizational components that CommonGround uses to facilitate shared decision-making, and we present a fidelity scale to assess how well the system is being implemented. PMID:28090194

  17. Dynamic segment shared protection for multicast traffic in meshed wavelength-division-multiplexing optical networks

    NASA Astrophysics Data System (ADS)

    Liao, Luhua; Li, Lemin; Wang, Sheng

    2006-12-01

    We investigate the protection approach for dynamic multicast traffic under shared risk link group (SRLG) constraints in meshed wavelength-division-multiplexing optical networks. We present a shared protection algorithm called dynamic segment shared protection for multicast traffic (DSSPM), which can dynamically adjust the link cost according to the current network state and can establish a primary light-tree as well as corresponding SRLG-disjoint backup segments for a dependable multicast connection. A backup segment can efficiently share the wavelength capacity of its working tree and the common resources of other backup segments based on SRLG-disjoint constraints. The simulation results show that DSSPM not only can protect the multicast sessions against a single-SRLG breakdown, but can make better use of the wavelength resources and also lower the network blocking probability.

  18. GOFC-GOLD/LCLUC/START Regional Networking: building capacity for science and decision-making.

    NASA Astrophysics Data System (ADS)

    Justice, C. O.; Vadrevu, K.; Gutman, G.

    2016-12-01

    Over the past 20 years, the international GOFC-GOLD Program and START, with core funding from the NASA LCLUC program and ESA have been developing regional networks of scientists and data users for scientific capacity building and sharing experience in the use and application of Earth Observation data. Regional networks connect scientists from countries with similar environmental and social issues and often with shared water and airsheds. Through periodic regional workshops, regional and national projects are showcased and national priorities and policy drivers are articulated. The workshops encourage both north-south and south-south exchange and collaboration. The workshops are multi-sponsored and each include a training component, targeting early career scientists and data users from the region. The workshops provide an opportunity for regional scientists to publish in peer-reviewed special editions focused on regional issues. Currently, the NASA LCLUC program funded "South and Southeast Asia Regional Initiative (SARI)" team is working closely with the USAID/NASA SERVIR program to implement some capacity building and training activities jointly in south/southeast Asian countries to achieve maximum benefit.

  19. Medicaid Expansion And Grant Funding Increases Helped Improve Community Health Center Capacity.

    PubMed

    Han, Xinxin; Luo, Qian; Ku, Leighton

    2017-01-01

    Through the expansion of Medicaid eligibility and increases in core federal grant funding, the Affordable Care Act (ACA) sought to increase the capacity of community health centers to provide primary care to low-income populations. We examined the effects of the ACA Medicaid expansion and changes in federal grant levels on the centers' numbers of patients, percentages of patients by type of insurance, and numbers of visits from 2012 to 2015. In the period after expansion (2014-15), health centers in expansion states had a 5 percent higher total patient volume, larger shares of Medicaid patients, smaller shares of uninsured patients, and increases in overall visits and mental health visits, compared to centers in nonexpansion states. Increases in federal grant funding levels were associated with increases in numbers of patients and of overall, medical, and preventive service visits. If federal grant levels are not sustained after 2017, there could be marked reductions in health center capacity in both expansion and nonexpansion states. Project HOPE—The People-to-People Health Foundation, Inc.

  20. Library and Information Networks: Centralization and Decentralization.

    ERIC Educational Resources Information Center

    Segal, JoAnn S.

    1988-01-01

    Describes the development of centralized library networks and the current factors that make library sharing on a smaller scale feasible. The discussion covers the need to decide the level at which library cooperation should occur and the possibility of linking via the Open System Interface Reference Model. (37 references) (CLB)

  1. Timbercrest Elementary and the University of Central Florida: From Theory into Practice--A School's Story

    ERIC Educational Resources Information Center

    Banta, Sarah; Cool, Mary; Hansen, Mary; Heckler, Jessica; Masker, Trish; Plavchan, Krista; Sobol, Michele; Blessing, Lew; Starzynski, Mary; Carr, Melissa

    2013-01-01

    From an informal discussion to being awarded the National Association for Professional Development School's Award for Exemplary Professional Development School Achievement, this article presents the story of the Timbercrest Elementary/University of Central Florida Professional Development School Partnership's journey. As the authors shared their…

  2. The Collaborative Capacity of the NYPD, FDNY, and EMS in New York City: A Focus on the First Line Officer

    DTIC Science & Technology

    2010-03-01

    of shared assumptions. Each respective agency has rituals and celebrations that reinforce traditions within an individualistic culture . The...to consider ways of enhancing members’ sense of shared values. Developing a more collectivistic culture , one that emphasizes the value of common...environment and to meet the challenges with all the homeland security partners. Different types of trust and influences of organizational cultures

  3. Levels of Social Sharing and Clinical Implications for Severe Social Withdrawal in Patients with Personality Disorders

    PubMed Central

    Colle, Livia; Pellecchia, Giovanni; Moroni, Fabio; Carcione, Antonino; Nicolò, Giuseppe; Semerari, Antonio; Procacci, Michele

    2017-01-01

    Social sharing capacities have attracted attention from a number of fields of social cognition and have been variously defined and analyzed in numerous studies. Social sharing consists in the subjective awareness that aspects of the self’s experience are held in common with other individuals. The definition of social sharing must take a variety of elements into consideration: the motivational element, the contents of the social sharing experience, the emotional responses it evokes, the behavioral outcomes, and finally, the circumstances and the skills which enable social sharing. The primary objective of this study is to explore some of the diverse forms of human social sharing and to classify them according to levels of complexity. We identify four different types of social sharing, categorized according to the nature of the content being shared and the complexity of the mindreading skills required. The second objective of this study is to consider possible applications of this graded model of social sharing experience in clinical settings. Specifically, this model may support the development of graded, focused clinical interventions for patients with personality disorders characterized by severe social withdrawal. PMID:29255430

  4. Implementation of a Centralized Patient Transfer Center: Improving the Care Experience of Patients and their Families

    DTIC Science & Technology

    2011-01-25

    Sharing Knowledge: Achieving Breakthrough Performance 2010 Military Health System Conference Implementation of a Centralized Patient Transfer...Improving the Care Experience of Patients and their Families Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the...Implementation of a Centralized Patient Transfer Center: Improving the Care Experience of Patients and their Families 5a. CONTRACT NUMBER 5b. GRANT

  5. East Europe Report

    DTIC Science & Technology

    1986-07-22

    trust’s system and by Kiril Zarev, BCP Central Committee secretary, Vasil Kalaydzhiev, secretary of the Central Committee of our trade union, and... Dimitrov and Bobov Dol combines, by 300,000 cubic meters each. We are not satisfied with the results of the organization and the efforts made by...institutes on the problems under discussion, Kiril Zarev, BCP Central Committee secretary, shared his thoughts on the ways and means for the successful

  6. Collective action in the management of a tropical dry forest ecosystem: effects of Mexico's property rights regime.

    PubMed

    Schroeder, Natalia Mariel; Castillo, Alicia

    2013-04-01

    Dilemmas of natural resources governance have been a central concern for scholars, policy makers, and users. Major debates occur over the implications of property rights for common resources management. After the Mexican Revolution (1910-1917), land was distributed mainly as ejidos conceived as a hereditary but unalienable collective form of property. In 1992, a new Agrarian Law was decreed that allows individual ownership by removing various restrictions over the transfer of land. Scholars have examined the reform mainly focusing on land-tenure changes and environmental fragmentation. This study examines how the new ownership regime is affecting collective decision-making in ejidos located in a tropical dry forest (TDF) ecosystem. Information on decision-making processes before and after the 1992 reform was gathered through 52 interviews conducted in four ejidos selected along a gradient including agricultural, cattle-raising, and TDF use. The new individualized land property system reduced collective action in ejidos but did not trigger it. Collective action responses to the 1992 reform were buffered by self-organization each ejido already had. Heterogeneous users who shared a short history and showed little understanding of TDF and low dependence on its resources seemed to explain why ejidos have not been able to share a sense of community that would shape the construction of institutions for the collective management of forest resources. However, when a resource is scarce and highly valuable such as water the same users showed capacities for undertaking costly co-operative activities.

  7. Collective Action in the Management of a Tropical Dry Forest Ecosystem: Effects of Mexico's Property Rights Regime

    NASA Astrophysics Data System (ADS)

    Schroeder, Natalia Mariel; Castillo, Alicia

    2013-04-01

    Dilemmas of natural resources governance have been a central concern for scholars, policy makers, and users. Major debates occur over the implications of property rights for common resources management. After the Mexican Revolution (1910-1917), land was distributed mainly as ejidos conceived as a hereditary but unalienable collective form of property. In 1992, a new Agrarian Law was decreed that allows individual ownership by removing various restrictions over the transfer of land. Scholars have examined the reform mainly focusing on land-tenure changes and environmental fragmentation. This study examines how the new ownership regime is affecting collective decision-making in ejidos located in a tropical dry forest (TDF) ecosystem. Information on decision-making processes before and after the 1992 reform was gathered through 52 interviews conducted in four ejidos selected along a gradient including agricultural, cattle-raising, and TDF use. The new individualized land property system reduced collective action in ejidos but did not trigger it. Collective action responses to the 1992 reform were buffered by self-organization each ejido already had. Heterogeneous users who shared a short history and showed little understanding of TDF and low dependence on its resources seemed to explain why ejidos have not been able to share a sense of community that would shape the construction of institutions for the collective management of forest resources. However, when a resource is scarce and highly valuable such as water the same users showed capacities for undertaking costly co-operative activities.

  8. Expenditure and Revenue Problems in Central-City School Districts: Problems for the 1980s.

    ERIC Educational Resources Information Center

    Murphy, Joseph F.; Hack, Walter G.

    1983-01-01

    Investigates the combination of expenditure and revenue problems facing central-city school districts. Examines educational overburden, related overburden, and cost differentials between central city and other types of districts. Also looks at tax capacity and efforts, and analyzes the effects of Federal and State activity on the problems of city…

  9. Where are we on the diffusion curve? Trends and drivers of primary care physicians' use of health information technology.

    PubMed

    Audet, Anne-Marie; Squires, David; Doty, Michelle M

    2014-02-01

    To describe trends in primary care physicians' use of health information technology (HIT) between 2009 and 2012, examine practice characteristics associated with greater HIT capacity in 2012, and explore factors such as delivery system and payment reforms that may affect adoption and functionality. We used data from the 2012 and 2009 Commonwealth Fund International Health Policy Surveys of Primary Care Physicians. The data were collected in both years by postal mail between March and July among a nationally representative sample of primary care physicians in the United States. We compared primary care physicians' HIT capacity in 2009 and 2012. We employed multivariable logistic regression to analyze whether participating in an integrated delivery system, sharing resources and support with other practices, and being eligible for financial incentives were associated with greater HIT capacity in 2012. Primary care physicians' HIT capacity has significantly expanded since 2009, although solo practices continue to lag. Practices that are part of an integrated delivery system or share resources with other practices have higher rates of electronic medical record (EMR) adoption, multifunctional HIT, electronic information exchange, and electronic access for patients. Receiving or being eligible for financial incentives is associated with greater adoption of EMRs and information exchange. Federal efforts to increase adoption have coincided with a rapid increase in HIT capacity. Delivery system and payment reforms and federally funded extension programs could offer promising pathways for further diffusion. © Health Research and Educational Trust.

  10. Promoting Shared Decision Making through Descriptive Inquiry

    ERIC Educational Resources Information Center

    Seher, Rachel; Traugh, Cecelia; Cheng, Alan

    2018-01-01

    This article shows how City-As-School, a progressive public school in New York City, used descriptive inquiry to deepen shared decision making, which is a central value of the school and part of a democratic way of life. Descriptive inquiry is a democratic knowledge-making process that was developed at the Prospect School in North Bennington,…

  11. Visual and Spatial Working Memory Are Not that Dissociated after All: A Time-Based Resource-Sharing Account

    ERIC Educational Resources Information Center

    Vergauwe, Evie; Barrouillet, Pierre; Camos, Valerie

    2009-01-01

    Examinations of interference between visual and spatial materials in working memory have suggested domain- and process-based fractionations of visuo-spatial working memory. The present study examined the role of central time-based resource sharing in visuo-spatial working memory and assessed its role in obtained interference patterns. Visual and…

  12. Putting It All Together: Learning for Work and Learning About Work in the Horticulture Industry.

    ERIC Educational Resources Information Center

    Trenerry, Ruth

    Literacy is a social practice central to sharing of knowledge and skills in the workplace. Workplaces increasingly demand workers who take on multiple roles and share and manage knowledge in new ways, so high levels of worker literacy and worker collaboration are increasingly important. Workplace training must facilitate development of active and…

  13. Auditory Short-Term Memory Capacity Correlates with Gray Matter Density in the Left Posterior STS in Cognitively Normal and Dyslexic Adults

    ERIC Educational Resources Information Center

    Richardson, Fiona M.; Ramsden, Sue; Ellis, Caroline; Burnett, Stephanie; Megnin, Odette; Catmur, Caroline; Schofield, Tom M.; Leff, Alex P.; Price, Cathy J.

    2011-01-01

    A central feature of auditory STM is its item-limited processing capacity. We investigated whether auditory STM capacity correlated with regional gray and white matter in the structural MRI images from 74 healthy adults, 40 of whom had a prior diagnosis of developmental dyslexia whereas 34 had no history of any cognitive impairment. Using…

  14. Developing a Capacity to Engage in Critical Reflection: Students' "Ways of Knowing" within an Undergraduate Business and Accounting Programme

    ERIC Educational Resources Information Center

    Lucas, Ursula; Tan, Phaik Leng

    2013-01-01

    The development of a capacity to engage in critical reflection is central to higher education. However, students vary in this capacity and its development requires students to move from an absolute towards a contextual way of knowing. Using 32 semi-structured interviews, this study identifies the ways of knowing of 17 business and accounting…

  15. Mental capacity and decision making: defining capacity.

    PubMed

    Dimond, Bridgit

    The Mental Capacity Act 2005 came fully into force on 1st October 2007 (some sections came into force on 1 April 2007). This series of articles considers some of the key features of the Act, including the concepts of best interests, the lasting power of attorney, the role of the new Court of Protection, the Office of Public Guardian and the deputies of the Court, to name but a few. This first article looks at the central feature of the Act: how mental capacity is determined.

  16. Effects of Scandinavian hydro power on storage needs in a fully renewable European power system for various transmission capacity scenarios

    NASA Astrophysics Data System (ADS)

    Kies, Alexander; Nag, Kabitri; von Bremen, Lueder; Lorenz, Elke; Heinemann, Detlev

    2015-04-01

    The penetration of renewable energies in the European power system has increased in the last decades (23.5% share of renewables in the gross electricity consumption of the EU-28 in 2012) and is expected to increase further up to very high shares close to 100%. Planning and organizing this European energy transition towards sustainable power sources will be one of the major challenges of the 21st century. It is very likely that in a fully renewable European power system wind and photovoltaics (pv) will contribute the largest shares to the generation mix followed by hydro power. However, feed-in from wind and pv is due to the weather dependant nature of their resources fluctuating and non-controllable. To match generation and consumption several solutions and their combinations were proposed like very high backup-capacities of conventional power generation (e.g. fossile or nuclear), storages or the extension of the transmission grid. Apart from those options hydro power can be used to counterbalance fluctuating wind and pv generation to some extent. In this work we investigate the effects of hydro power from Norway and Sweden on residual storage needs in Europe depending on the overlaying grid scenario. High temporally and spatially resolved weather data with a spatial resolution of 7 x 7 km and a temporal resolution of 1 hour was used to model the feed-in from wind and pv for 34 investigated European countries for the years 2003-2012. Inflow into hydro storages and generation by run-of-river power plants were computed from ERA-Interim reanalysis runoff data at a spatial resolution of 0.75° x 0.75° and a daily temporal resolution. Power flows in a simplified transmission grid connecting the 34 European countries were modelled minimizing dissipation using a DC-flow approximation. Previous work has shown that hydro power, namely in Norway and Sweden, can reduce storage needs in a renewable European power system by a large extent. A 15% share of hydro power in Europe can reduce storage needs by up to 50% with respect to stored energy. This requires however large transmission capacities between the major hydro power producers in Scandinavia and the largest consumers of electrical energy in Western Europe. We show how Scandinavian hydro power can reduce storage needs in dependency of the transmission grid for two fully renewable scenarios: The first one has its wind and pv generation capacities distributed according to an empirically derived approach. The second scenario has an optimal spatial distribution to minimize storage needs distribution of wind and pv generation capacities across Europe. We show that in both cases hydro power together with a well developed transmission grid has the potential to contribute a large share to the solution of the generation-consumption mismatch problem. The work is part of the RESTORE 2050 project (BMBF) that investigates the requirements for cross-country grid extensions, usage of storage technologies and capacities and the development of new balancing technologies.

  17. High-cost, high-capacity backbone for global brain communication.

    PubMed

    van den Heuvel, Martijn P; Kahn, René S; Goñi, Joaquín; Sporns, Olaf

    2012-07-10

    Network studies of human brain structural connectivity have identified a specific set of brain regions that are both highly connected and highly central. Recent analyses have shown that these putative hub regions are mutually and densely interconnected, forming a "rich club" within the human brain. Here we show that the set of pathways linking rich club regions forms a central high-cost, high-capacity backbone for global brain communication. Diffusion tensor imaging (DTI) data of two sets of 40 healthy subjects were used to map structural brain networks. The contributions to network cost and communication capacity of global cortico-cortical connections were assessed through measures of their topology and spatial embedding. Rich club connections were found to be more costly than predicted by their density alone and accounted for 40% of the total communication cost. Furthermore, 69% of all minimally short paths between node pairs were found to travel through the rich club and a large proportion of these communication paths consisted of ordered sequences of edges ("path motifs") that first fed into, then traversed, and finally exited the rich club, while passing through nodes of increasing and then decreasing degree. The prevalence of short paths that follow such ordered degree sequences suggests that neural communication might take advantage of strategies for dynamic routing of information between brain regions, with an important role for a highly central rich club. Taken together, our results show that rich club connections make an important contribution to interregional signal traffic, forming a central high-cost, high-capacity backbone for global brain communication.

  18. COINSTAC: A Privacy Enabled Model and Prototype for Leveraging and Processing Decentralized Brain Imaging Data.

    PubMed

    Plis, Sergey M; Sarwate, Anand D; Wood, Dylan; Dieringer, Christopher; Landis, Drew; Reed, Cory; Panta, Sandeep R; Turner, Jessica A; Shoemaker, Jody M; Carter, Kim W; Thompson, Paul; Hutchison, Kent; Calhoun, Vince D

    2016-01-01

    The field of neuroimaging has embraced the need for sharing and collaboration. Data sharing mandates from public funding agencies and major journal publishers have spurred the development of data repositories and neuroinformatics consortia. However, efficient and effective data sharing still faces several hurdles. For example, open data sharing is on the rise but is not suitable for sensitive data that are not easily shared, such as genetics. Current approaches can be cumbersome (such as negotiating multiple data sharing agreements). There are also significant data transfer, organization and computational challenges. Centralized repositories only partially address the issues. We propose a dynamic, decentralized platform for large scale analyses called the Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymous Computation (COINSTAC). The COINSTAC solution can include data missing from central repositories, allows pooling of both open and "closed" repositories by developing privacy-preserving versions of widely-used algorithms, and incorporates the tools within an easy-to-use platform enabling distributed computation. We present an initial prototype system which we demonstrate on two multi-site data sets, without aggregating the data. In addition, by iterating across sites, the COINSTAC model enables meta-analytic solutions to converge to "pooled-data" solutions (i.e., as if the entire data were in hand). More advanced approaches such as feature generation, matrix factorization models, and preprocessing can be incorporated into such a model. In sum, COINSTAC enables access to the many currently unavailable data sets, a user friendly privacy enabled interface for decentralized analysis, and a powerful solution that complements existing data sharing solutions.

  19. COINSTAC: A Privacy Enabled Model and Prototype for Leveraging and Processing Decentralized Brain Imaging Data

    PubMed Central

    Plis, Sergey M.; Sarwate, Anand D.; Wood, Dylan; Dieringer, Christopher; Landis, Drew; Reed, Cory; Panta, Sandeep R.; Turner, Jessica A.; Shoemaker, Jody M.; Carter, Kim W.; Thompson, Paul; Hutchison, Kent; Calhoun, Vince D.

    2016-01-01

    The field of neuroimaging has embraced the need for sharing and collaboration. Data sharing mandates from public funding agencies and major journal publishers have spurred the development of data repositories and neuroinformatics consortia. However, efficient and effective data sharing still faces several hurdles. For example, open data sharing is on the rise but is not suitable for sensitive data that are not easily shared, such as genetics. Current approaches can be cumbersome (such as negotiating multiple data sharing agreements). There are also significant data transfer, organization and computational challenges. Centralized repositories only partially address the issues. We propose a dynamic, decentralized platform for large scale analyses called the Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymous Computation (COINSTAC). The COINSTAC solution can include data missing from central repositories, allows pooling of both open and “closed” repositories by developing privacy-preserving versions of widely-used algorithms, and incorporates the tools within an easy-to-use platform enabling distributed computation. We present an initial prototype system which we demonstrate on two multi-site data sets, without aggregating the data. In addition, by iterating across sites, the COINSTAC model enables meta-analytic solutions to converge to “pooled-data” solutions (i.e., as if the entire data were in hand). More advanced approaches such as feature generation, matrix factorization models, and preprocessing can be incorporated into such a model. In sum, COINSTAC enables access to the many currently unavailable data sets, a user friendly privacy enabled interface for decentralized analysis, and a powerful solution that complements existing data sharing solutions. PMID:27594820

  20. Spatial navigation, episodic memory, episodic future thinking, and theory of mind in children with autism spectrum disorder: evidence for impairments in mental simulation?

    PubMed Central

    Lind, Sophie E.; Bowler, Dermot M.; Raber, Jacob

    2014-01-01

    This study explored spatial navigation alongside several other cognitive abilities that are thought to share common underlying neurocognitive mechanisms (e.g., the capacity for self-projection, scene construction, or mental simulation), and which we hypothesized may be impaired in autism spectrum disorder (ASD). Twenty intellectually high-functioning children with ASD (with a mean age of ~8 years) were compared to 20 sex, age, IQ, and language ability matched typically developing children on a series of tasks to assess spatial navigation, episodic memory, episodic future thinking (also known as episodic foresight or prospection), theory of mind (ToM), relational memory, and central coherence. This is the first study to explore these abilities concurrently within the same sample. Spatial navigation was assessed using the “memory island” task, which involves finding objects within a realistic, computer simulated, three-dimensional environment. Episodic memory and episodic future thinking were assessed using a past and future event description task. ToM was assessed using the “animations” task, in which children were asked to describe the interactions between two animated triangles. Relational memory was assessed using a recognition task involving memory for items (line drawings), patterned backgrounds, or combinations of items and backgrounds. Central coherence was assessed by exploring differences in performance across segmented and unsegmented versions of block design. Children with ASD were found to show impairments in spatial navigation, episodic memory, episodic future thinking, and central coherence, but not ToM or relational memory. Among children with ASD, spatial navigation was found to be significantly negatively related to the number of repetitive behaviors. In other words, children who showed more repetitive behaviors showed poorer spatial navigation. The theoretical and practical implications of the results are discussed. PMID:25538661

  1. Spatial navigation, episodic memory, episodic future thinking, and theory of mind in children with autism spectrum disorder: evidence for impairments in mental simulation?

    PubMed

    Lind, Sophie E; Bowler, Dermot M; Raber, Jacob

    2014-01-01

    This study explored spatial navigation alongside several other cognitive abilities that are thought to share common underlying neurocognitive mechanisms (e.g., the capacity for self-projection, scene construction, or mental simulation), and which we hypothesized may be impaired in autism spectrum disorder (ASD). Twenty intellectually high-functioning children with ASD (with a mean age of ~8 years) were compared to 20 sex, age, IQ, and language ability matched typically developing children on a series of tasks to assess spatial navigation, episodic memory, episodic future thinking (also known as episodic foresight or prospection), theory of mind (ToM), relational memory, and central coherence. This is the first study to explore these abilities concurrently within the same sample. Spatial navigation was assessed using the "memory island" task, which involves finding objects within a realistic, computer simulated, three-dimensional environment. Episodic memory and episodic future thinking were assessed using a past and future event description task. ToM was assessed using the "animations" task, in which children were asked to describe the interactions between two animated triangles. Relational memory was assessed using a recognition task involving memory for items (line drawings), patterned backgrounds, or combinations of items and backgrounds. Central coherence was assessed by exploring differences in performance across segmented and unsegmented versions of block design. Children with ASD were found to show impairments in spatial navigation, episodic memory, episodic future thinking, and central coherence, but not ToM or relational memory. Among children with ASD, spatial navigation was found to be significantly negatively related to the number of repetitive behaviors. In other words, children who showed more repetitive behaviors showed poorer spatial navigation. The theoretical and practical implications of the results are discussed.

  2. An assessment of potential hydro-political tensions in transboundary river basins using environmental, political, and economic indicators

    NASA Astrophysics Data System (ADS)

    De Stefano, Lucia; Petersen-Perlman, Jacob; Sproles, Eric; Eynard, James; Wolf, Aaron T.

    2015-04-01

    Globally 286 river basins extend across international borders, covering over 61.9 million km2 of the earth's surface and hosting a total of approximately 2.7 billion people. In these basins, transboundary water resources support an interdependent web of environmental, political, and economic systems that can enhance or destabilize a region. We present an integrated global-scale assessment of transboundary watersheds to identify regions more likely to experience hydro-political tensions over the next decade and beyond based upon environmental, political, and economic indicators. We combine NASA's Gravity Recovery and Climate Experiment (GRACE) measurements of changes in terrestrial water storage with metrics of projected climate change impacts on water variability, the institutional capacity of countries to manage shared water resources, the development of new water infrastructure, per capita gross national income, domestic and international armed conflicts, and recent history of disputes over transboundary waters. The construction of new water-related infrastructure is on-going or planned in many basins worldwide. New water infrastructure is foreseen also in areas where instruments of international cooperation are still absent or limited in scope, e.g. in Southeast Asia, South Asia, Central America, the northern part of the South American continent, and the southern Balkans as well as in different parts of Africa. Moreover, in Central and Eastern Africa, the Middle East, and Central, South and South-East Asia there is a concomitance of several political, environmental and socioeconomic factors that could exacerbate hydropolitical tensions. Our analysis integrates political, economic and environmental metrics and is part of the United Nation's Transboundary Waters Assessment Programme to provide the first global-scale assessment of its type.

  3. Food load manipulation ability shapes flight morphology in females of central-place foraging Hymenoptera

    PubMed Central

    2013-01-01

    Background Ecological constraints related to foraging are expected to affect the evolution of morphological traits relevant to food capture, manipulation and transport. Females of central-place foraging Hymenoptera vary in their food load manipulation ability. Bees and social wasps modulate the amount of food taken per foraging trip (in terms of e.g. number of pollen grains or parts of prey), while solitary wasps carry exclusively entire prey items. We hypothesized that the foraging constraints acting on females of the latter species, imposed by the upper limit to the load size they are able to transport in flight, should promote the evolution of a greater load-lifting capacity and manoeuvrability, specifically in terms of greater flight muscle to body mass ratio and lower wing loading. Results Our comparative study of 28 species confirms that, accounting for shared ancestry, female flight muscle ratio was significantly higher and wing loading lower in species taking entire prey compared to those that are able to modulate load size. Body mass had no effect on flight muscle ratio, though it strongly and negatively co-varied with wing loading. Across species, flight muscle ratio and wing loading were negatively correlated, suggesting coevolution of these traits. Conclusions Natural selection has led to the coevolution of resource load manipulation ability and morphological traits affecting flying ability with additional loads in females of central-place foraging Hymenoptera. Release from load-carrying constraints related to foraging, which took place with the evolution of food load manipulation ability, has selected against the maintenance of a powerful flight apparatus. This could be the case since investment in flight muscles may have to be traded against other life-history traits, such as reproductive investment. PMID:23805850

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    A new generation of central, ducted variable-capacity heat pump systems has come on the market, promising very high cooling and heating efficiency. Instead of cycling on at full capacity and then cycling off when the thermostat is satisfied, they vary their cooling and heating output over a wide range (approximately 40 to 118% of nominal full capacity); thus, staying 'on' for 60% to 100% more hours per day compared to fixed-capacity systems. Current Phase 4 experiments in an instrumented lab home with simulated occupancy evaluate the impact of duct R-value enhancement on the overall operating efficiency of the variable-capacity systemmore » compared to the fixed-capacity system.« less

  5. Ancient DNA Reveals Matrilineal Continuity in Present-Day Poland over the Last Two Millennia

    PubMed Central

    Juras, Anna; Dabert, Miroslawa; Kushniarevich, Alena; Malmström, Helena; Raghavan, Maanasa; Kosicki, Jakub Z.; Metspalu, Ene; Willerslev, Eske; Piontek, Janusz

    2014-01-01

    While numerous ancient human DNA datasets from across Europe have been published till date, modern-day Poland in particular, remains uninvestigated. Besides application in the reconstruction of continent-wide human history, data from this region would also contribute towards our understanding of the history of the Slavs, whose origin is hypothesized to be in East or Central Europe. Here, we present the first population-scale ancient human DNA study from the region of modern-day Poland by establishing mitochondrial DNA profiles for 23 samples dated to 200 BC – 500 AD (Roman Iron Age) and for 20 samples dated to 1000–1400 AD (Medieval Age). Our results show that mitochondrial DNA sequences from both periods belong to haplogroups that are characteristic of contemporary West Eurasia. Haplotype sharing analysis indicates that majority of the ancient haplotypes are widespread in some modern Europeans, including Poles. Notably, the Roman Iron Age samples share more rare haplotypes with Central and Northeast Europeans, whereas the Medieval Age samples share more rare haplotypes with East-Central and South-East Europeans, primarily Slavic populations. Our data demonstrates genetic continuity of certain matrilineages (H5a1 and N1a1a2) in the area of present-day Poland from at least the Roman Iron Age until present. As such, the maternal gene pool of present-day Poles, Czechs and Slovaks, categorized as Western Slavs, is likely to have descended from inhabitants of East-Central Europe during the Roman Iron Age. PMID:25337992

  6. KSC-04PD-0250

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. NASA Administrator Sean OKeefe (center) is welcomed to the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  7. KSC-04PD-0270

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. After a presentation about the assets of the Central Florida Research Park, near Orlando, as the site of NASAs new Shared Services Center, Congressmen Tom Feeney (center) and Dave Weldon (right) share a humorous moment with NASA Administrator Sean OKeefe (foreground). Six sites around the U.S. are under consideration for location of the Center, which would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Others attending the presentation included Congressman Dave Weldon, U.S. Representative Ric Keller, Center Director Jim Kennedy and Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida.

  8. Benefit sharing: it's time for a definition.

    PubMed

    Schroeder, D

    2007-04-01

    Benefit sharing has been a recurrent theme in international debates for the past two decades. However, despite its prominence in law, medical ethics and political philosophy, the concept has never been satisfactorily defined. In this conceptual paper, a definition that combines current legal guidelines with input from ethics debates is developed. Philosophers like boxes; protective casings into which they can put concisely-defined concepts. Autonomy is the human capacity for self-determination; beneficence denotes the virtue of good deeds, coercion is the intentional threat of harm and so on. What about benefit sharing? Does the concept have a box and are the contents clearly defined? The answer to this question has to be no. The concept of benefit sharing is almost unique in that various disciplines use it regularly without precise definitions. In this article, a definition for benefit sharing is provided, to eliminate unnecessary ambiguity.

  9. Benefit sharing: it's time for a definition

    PubMed Central

    Schroeder, D

    2007-01-01

    Benefit sharing has been a recurrent theme in international debates for the past two decades. However, despite its prominence in law, medical ethics and political philosophy, the concept has never been satisfactorily defined. In this conceptual paper, a definition that combines current legal guidelines with input from ethics debates is developed. Philosophers like boxes; protective casings into which they can put concisely‐defined concepts. Autonomy is the human capacity for self‐determination; beneficence denotes the virtue of good deeds, coercion is the intentional threat of harm and so on. What about benefit sharing? Does the concept have a box and are the contents clearly defined? The answer to this question has to be no. The concept of benefit sharing is almost unique in that various disciplines use it regularly without precise definitions. In this article, a definition for benefit sharing is provided, to eliminate unnecessary ambiguity. PMID:17400617

  10. Job sharing for women pharmacists in academia.

    PubMed

    Rogers, Kelly C; Finks, Shannon W

    2009-11-12

    The pharmacist shortage, increasing numbers of female pharmacy graduates, more pharmacy schools requiring faculty members, and a lower percentage of female faculty in academia are reasons to develop unique arrangements for female academic pharmacists who wish to work part-time. Job sharing is an example of a flexible alternative work arrangement that can be successful for academic pharmacists who wish to continue in a part-time capacity. Such partnerships have worked for other professionals but have not been widely adopted in pharmacy academia. Job sharing can benefit the employer through retention of experienced employees who collectively offer a wider range of skills than a single employee. Benefits to the employee include balanced work and family lives with the ability to maintain their knowledge and skills by remaining in the workforce. We discuss the additional benefits of job-sharing as well as our experience in a non-tenure track job-sharing position at the University of Tennessee College of Pharmacy.

  11. On the Roles of External Knowledge Representations in Assessment Design

    ERIC Educational Resources Information Center

    Mislevy, Robert J.; Behrens, John T.; Bennett, Randy E.; Demark, Sarah F.; Frezzo, Dennis C.; Levy, Roy; Robinson, Daniel H.; Rutstein, Daisy Wise; Shute, Valerie J.; Stanley, Ken; Winters, Fielding I.

    2010-01-01

    People use external knowledge representations (KRs) to identify, depict, transform, store, share, and archive information. Learning how to work with KRs is central to be-coming proficient in virtually every discipline. As such, KRs play central roles in curriculum, instruction, and assessment. We describe five key roles of KRs in assessment: (1)…

  12. On the Roles of External Knowledge Representations in Assessment Design. CSE Report 722

    ERIC Educational Resources Information Center

    Mislevy, Robert J.; Behrens, John T.; Bennett, Randy E.; Demark, Sarah F.; Frezzo, Dennis C.; Levy, Roy; Robinson, Daniel H.; Rutstein, Daisy Wise; Shute, Valerie J.; Stanley, Ken; Winters, Fielding I.

    2007-01-01

    People use external knowledge representations (EKRs) to identify, depict, transform, store, share, and archive information. Learning how to work with EKRs is central to becoming proficient in virtually every discipline. As such, EKRs play central roles in curriculum, instruction, and assessment. Five key roles of EKRs in educational assessment are…

  13. Health policies and federative gaps in Brazil: an analysis of regional capacity of services delivery.

    PubMed

    Ribeiro, José Mendes; Moreira, Marcelo Rasga; Ouverney, Assis Mafort; Silva, Cosme Marcelo Furtado Passos da

    2017-04-01

    This paper analyzes Brazilian health regions according to their service delivery capacity from the debate on the crisis of cooperative federalism in the SUS that resulted from decentralizing process established in the 1988 Constitution. Service delivery capacity tracer indicators were selected by regions and statistical analyses evidenced greater regional capacity in hospital care and large asymmetries with regard to the availability of physicians, high complexity equipment and private insurance coverage. In conclusion,we argue that further solutions are required to strengthen governmental capacity to reduce regional inequalities throughincreased central coordination.

  14. KENNEDY SPACE CENTER, FLA. - Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida, takes part in the proposal for locating NASA’s new Shared Services Center in the Central Florida Research Park, near Orlando. The presentation was given to NASA Administrator Sean O’Keefe and other officials. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida, takes part in the proposal for locating NASA’s new Shared Services Center in the Central Florida Research Park, near Orlando. The presentation was given to NASA Administrator Sean O’Keefe and other officials. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  15. Moving beyond Bermuda: sharing data to build a medical information commons.

    PubMed

    Cook-Deegan, Robert; McGuire, Amy L

    2017-06-01

    The ubiquity of DNA sequencing and the advent of medical imaging, electronic health records, and "omics" technologies have produced a deluge of data. Making meaning of those data-creating scientific knowledge and useful clinical information-will vastly exceed the capacity of even the largest institutions. Data must be shared to achieve the promises of genomic science and precision medicine. © 2017 Cook-Deegan and McGuire; Published by Cold Spring Harbor Laboratory Press.

  16. CORE-SINEs: eukaryotic short interspersed retroposing elements with common sequence motifs.

    PubMed

    Gilbert, N; Labuda, D

    1999-03-16

    A 65-bp "core" sequence is dispersed in hundreds of thousands copies in the human genome. This sequence was found to constitute the central segment of a group of short interspersed elements (SINEs), referred to as mammalian-wide interspersed repeats, that proliferated before the radiation of placental mammals. Here, we propose that the core identifies an ancient tRNA-like SINE element, which survived in different lineages such as mammals, reptiles, birds, and fish, as well as mollusks, presumably for >550 million years. This element gave rise to a number of sequence families (CORE-SINEs), including mammalian-wide interspersed repeats, whose distinct 3' ends are shared with different families of long interspersed elements (LINEs). The evolutionary success of the generic CORE-SINE element can be related to the recruitment of the internal promoter from highly transcribed host RNA as well as to its capacity to adapt to changing retropositional opportunities by sequence exchange with actively amplifying LINEs. It reinforces the notion that the very existence of SINEs depends on the cohabitation with both LINEs and the host genome.

  17. CORE-SINEs: Eukaryotic short interspersed retroposing elements with common sequence motifs

    PubMed Central

    Gilbert, Nicolas; Labuda, Damian

    1999-01-01

    A 65-bp “core” sequence is dispersed in hundreds of thousands copies in the human genome. This sequence was found to constitute the central segment of a group of short interspersed elements (SINEs), referred to as mammalian-wide interspersed repeats, that proliferated before the radiation of placental mammals. Here, we propose that the core identifies an ancient tRNA-like SINE element, which survived in different lineages such as mammals, reptiles, birds, and fish, as well as mollusks, presumably for >550 million years. This element gave rise to a number of sequence families (CORE-SINEs), including mammalian-wide interspersed repeats, whose distinct 3′ ends are shared with different families of long interspersed elements (LINEs). The evolutionary success of the generic CORE-SINE element can be related to the recruitment of the internal promoter from highly transcribed host RNA as well as to its capacity to adapt to changing retropositional opportunities by sequence exchange with actively amplifying LINEs. It reinforces the notion that the very existence of SINEs depends on the cohabitation with both LINEs and the host genome. PMID:10077603

  18. Endoplasmic reticulum proteostasis impairment in aging.

    PubMed

    Martínez, Gabriela; Duran-Aniotz, Claudia; Cabral-Miranda, Felipe; Vivar, Juan P; Hetz, Claudio

    2017-08-01

    Perturbed neuronal proteostasis is a salient feature shared by both aging and protein misfolding disorders. The proteostasis network controls the health of the proteome by integrating pathways involved in protein synthesis, folding, trafficking, secretion, and their degradation. A reduction in the buffering capacity of the proteostasis network during aging may increase the risk to undergo neurodegeneration by enhancing the accumulation of misfolded proteins. As almost one-third of the proteome is synthetized at the endoplasmic reticulum (ER), maintenance of its proper function is fundamental to sustain neuronal function. In fact, ER stress is a common feature of most neurodegenerative diseases. The unfolded protein response (UPR) operates as central player to maintain ER homeostasis or the induction of cell death of chronically damaged cells. Here, we discuss recent evidence placing ER stress as a driver of brain aging, and the emerging impact of neuronal UPR in controlling global proteostasis at the whole organismal level. Finally, we discuss possible therapeutic interventions to improve proteostasis and prevent pathological brain aging. © 2017 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  19. Global HIV/AIDS funding and health systems: Searching for the win-win.

    PubMed

    Levine, Ruth; Oomman, Nandini

    2009-11-01

    Donors, developing country governments, and NGOs are searching for ways to use funding for HIV/AIDS programs that strengthen the functioning of weak health systems. This is motivated both by the realization that a large share of donor funding for global health is and will continue to be dedicated to HIV/AIDS, and that the aims of more and better treatment, prevention, and care can be achieved only with attention to systemic capacities. For AIDS resources to strengthen health systems, decision makers should: (a) mitigate the risks that AIDS spending may weaken the ability of health systems to respond to other health problems; (b) find ways for procurement, supply chain, management information, and other systems that are created to support AIDS treatment to be broadened to serve other types of services; and (c) build upon the ways in which AIDS programs have overcome some demand-side barriers to use of services. In pursuing this agenda, donors should recognize that health system development is a function of the national and local political economy and place respect for national sovereignty as a central tenet of their policies and practices.

  20. A Word to the Wise: Advice for Scientists Engaged in Collaborative Adaptive Management

    NASA Astrophysics Data System (ADS)

    Hopkinson, Peter; Huber, Ann; Saah, David S.; Battles, John J.

    2017-05-01

    Collaborative adaptive management is a process for making decisions about the environment in the face of uncertainty and conflict. Scientists have a central role to play in these decisions. However, while scientists are well trained to reduce uncertainty by discovering new knowledge, most lack experience with the means to mitigate conflict in contested situations. To address this gap, we drew from our efforts coordinating a large collaborative adaptive management effort, the Sierra Nevada Adaptive Management Project, to offer advice to our fellow environmental scientists. Key challenges posed by collaborative adaptive management include the confusion caused by multiple institutional cultures, the need to provide information at management-relevant scales, frequent turnover in participants, fluctuations in enthusiasm among key constituencies, and diverse definitions of success among partners. Effective strategies included a dedication to consistency, a commitment to transparency, the willingness to communicate frequently via multiple forums, and the capacity for flexibility. Collaborative adaptive management represents a promising, new model for scientific engagement with the public. Learning the lessons of effective collaboration in environmental management is an essential task to achieve the shared goal of a sustainable future.

  1. Solar PV O&M Standards and Best Practices – Existing Gaps and Improvement Efforts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klise, Geoffrey Taylor; Balfour, John R.; Keating, T. J.

    2014-11-01

    As greater numbers of photovoltaic (PV) systems are being installed, operations & maintenance (O&M) activities will need to be performed to ensure the PV system is operating as designed over its useful lifetime. To mitigate risks to PV system availability and performance, standardized procedures for O&M activities are needed to ensure high reliability and long-term system bankability. Efforts are just getting underway to address the need for standard O&M procedures as PV gains a larger share of U.S. generation capacity. Due to the existing landscape of how and where PV is installed, including distributed generation from small and medium PVmore » systems, as well as large, centralized utility-scale PV, O&M activities will require different levels of expertise and reporting, making standards even more important. This report summarizes recent efforts made by solar industry stakeholders to identify the existing standards and best practices applied to solar PV O&M activities, and determine the gaps that have yet to be, or are currently being addressed by industry.« less

  2. Solar PV O&M Standards and Best Practices - Existing Gaps and Improvement Efforts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klise, Geoffrey Taylor; Balfour, John R.; Keating, T. J.

    2014-11-01

    As greater numbers of photovoltaic (PV) systems are being installed, operations & maintenance (O&M) activities will need to be performed to ensure the PV system is operating as designed over its useful lifetime. To mitigate risks to PV system availability and performance, standardized procedures for O&M activities are needed to ensure high reliability and long-term system bankability. Efforts are just getting underway to address the need for standard O&M procedures as PV gains a larger share of U.S. generation capacity. Due to the existing landscape of how and where PV is installed, including distributed generation from small and medium PVmore » systems, as well as large, centralized utility-scale PV, O&M activities will require different levels of expertise and reporting, making standards even more important. This report summarizes recent efforts made by solar industry stakeholders to identify the existing standards and best practices applied to solar PV O&M activities, and determine the gaps that have yet to be, or are currently being addressed by industry.« less

  3. Realising the ICPD 20 years later: shifting the paradigms for research and education.

    PubMed

    Gruskin, Sofia; Ravindran, T K Sundari

    2014-01-01

    The extent to which people can enjoy their sexual and reproductive health is invariably intertwined with issues of disadvantage, inequality and human rights. Increased conservatism, lack of political will, outright resistance and the limited incorporation of human rights norms and standards into sexual and reproductive health policies and programmes are central challenges. Building capacity and skills to understand and address the range of issues raised by sexual and reproductive health and rights is of critical importance. Committed to the principles underlying the ICPD agenda and heavily involved in research and education, with a shared desire to bring global attention to the need for gender- and rights-oriented research and training in sexual and reproductive health, a group of us came together to form the Rights-Oriented Research and Education (RORE) Network for Sexual and Reproductive Health at the end of 2012. To generate dialogue, discussion and action, we propose what we mean by a human rights orientation to sexual and reproductive health and what we believe is needed going forward to achieve a human rights orientation to sexual and reproductive health education and research.

  4. Thoughts on the development of active regional public health systems.

    PubMed

    Reis, Ademar Arthur Chioro Dos; Sóter, Ana Paula Menezes; Furtado, Lumena Almeida Castro; Pereira, Silvana Souza da Silva

    2017-04-01

    Decentralization and regionalization are strategic themes for reforms in the health system. This paper analyzes the complex process of health regionalization being developed in Brazil. This paper identifies that the normative framework from the Brazilian National Health System, SUS has made advances with respect to its institutionalization and overcoming the initial centrality involved in municipalization. This has strengthened the development of regionalization and the intergovernmental agreement on health but the evidence points to the need to promote a revision. Based on document analysis, literature review and the views given by the authors involved in management in SUS as well as generating radically different views, the challenges for the construction of a regionalization that is active, is debated. We also discuss: its relations with planning and the dimensioning of service networks, the production of active care networks and shared management spaces, the inter-federative agreements and regional regulations, the capacity to coordinate regional systems and financing and the impact of the political dimension and electoral cycles. Regionalization (and SUS itself) is an open book, therefore ways and possibilities on how to maintain an active form of regionalization can be recommended.

  5. The Endemic Treponematoses

    PubMed Central

    Giacani, Lorenzo

    2014-01-01

    SUMMARY The agents of human treponematoses include four closely related members of the genus Treponema: three subspecies of Treponema pallidum plus Treponema carateum. T. pallidum subsp. pallidum causes venereal syphilis, while T. pallidum subsp. pertenue, T. pallidum subsp. endemicum, and T. carateum are the agents of the endemic treponematoses yaws, bejel (or endemic syphilis), and pinta, respectively. All human treponematoses share remarkable similarities in pathogenesis and clinical manifestations, consistent with the high genetic and antigenic relatedness of their etiological agents. Distinctive features have been identified in terms of age of acquisition, most common mode of transmission, and capacity for invasion of the central nervous system and fetus, although the accuracy of these purported differences is debated among investigators and no biological basis for these differences has been identified to date. In 2012, the World Health Organization (WHO) officially set a goal for yaws eradication by 2020. This challenging but potentially feasible endeavor is favored by the adoption of oral azithromycin for mass treatment and the currently focused distribution of yaws and endemic treponematoses and has revived global interest in these fascinating diseases and their causative agents. PMID:24396138

  6. Capacity development for health research in Africa: experiences managing the African Doctoral Dissertation Research Fellowship Program

    PubMed Central

    2010-01-01

    Africa's progress depends on her capacity to generate, adapt, and use scientific knowledge to meet regional health and development needs. Yet, Africa's higher education institutions that are mandated to foster this capacity lack adequate resources to generate and apply knowledge, raising the need for innovative approaches to enhance research capacity. In this paper, we describe a newly-developed program to support PhD research in health and population sciences at African universities, the African Doctoral Dissertation Research Fellowship (ADDRF) Program. We also share our experiences implementing the program. As health research capacity-strengthening in Africa continues to attract attention and as the need for such programs to be African-led is emphasized, our experiences in developing and implementing the ADDRF offer invaluable lessons to other institutions undertaking similar initiatives. PMID:20587016

  7. Demonstration and Evaluation of the Effects of Incentives on Resource Sharing Using a Computerized Interlibrary Communications System.

    ERIC Educational Resources Information Center

    New England Board of Higher Education, Wellesley, MA. New England Library Information Network.

    The potential for using a computerized communication system to facilitate resource sharing in New England has been investigated by the staff of the New England Information Network (NELINET). The central purpose of their research was to determine whether a strategy for load leveling of interlibrary loan (ILL) requests could be implemented online as…

  8. Collective Designing and Sharing of Open Educational Resources: A Study of the French CARTOUN Platform

    ERIC Educational Resources Information Center

    Quere, Nolwenn

    2017-01-01

    Designing and sharing Open Educational Resources (OERs) requires teachers to develop new competences, in particular with digital resources. In this paper, the case of a language resource production group is introduced. Due to the centrality of the OERs in their collective activity, I show that the documents they produce are essential to the…

  9. Central Sensitivity Syndromes: Mounting Pathophysiologic Evidence to Link Fibromyalgia with other Common Chronic Pain Disorders

    PubMed Central

    Kindler, Lindsay L.; Bennett, Robert M.; Jones, Kim D.

    2009-01-01

    Objective To review emerging data from the fields of nursing, rheumatology, dentistry, gastroenterology, gynecology, neurology, and orthopedics that supports or disputes pathophysiologic similarities in pain syndromes studied by each specialty. Methods A literature search was performed through PubMed and Ovid using the terms fibromyalgia, temporomandibular joint disorder, irritable bowel syndrome, irritable bladder/interstitial cystitis, headache, chronic low back pain, chronic neck pain, functional syndromes and somatization. Each term was linked with pathophysiology and/or central sensitization. This paper presents a review of relevant articles with a specific goal of identifying pathophysiological findings related to nociceptive processing. Results The extant literature presents considerable overlap in the pathophysiology of these diagnoses. Given the psychosomatic lens through which many of these disorders are viewed, demonstration of evidence based links supporting shared pathophysiology between these disorders could provide direction to clinicians and researchers working to treat these diagnoses. Conclusions Central sensitivity syndromes denotes an emerging nomenclature that could be embraced by researchers investigating each of these disorders. Moreover, a shared paradigm would be useful in promoting cross-fertilization between researchers. Scientists and clinicians could most effectively forward the understanding and treatment of fibromyalgia and other common chronic pain disorders through an appreciation of their shared pathophysiology. PMID:21349445

  10. Heuristic approaches for energy-efficient shared restoration in WDM networks

    NASA Astrophysics Data System (ADS)

    Alilou, Shahab

    In recent years, there has been ongoing research on the design of energy-efficient Wavelength Division Multiplexing (WDM) networks. The explosive growth of Internet traffic has led to increased power consumption of network components. Network survivability has also been a relevant research topic, as it plays a crucial role in assuring continuity of service with no disruption, regardless of network component failure. Network survivability mechanisms tend to utilize considerable resources such as spare capacity in order to protect and restore information. This thesis investigates techniques for reducing energy demand and enhancing energy efficiency in the context of network survivability. We propose two novel heuristic energy-efficient shared protection approaches for WDM networks. These approaches intend to save energy by setting on sleep mode devices that are not being used while providing shared backup paths to satisfy network survivability. The first approach exploits properties of a math series in order to assign weight to the network links. It aims at reducing power consumption at the network indirectly by aggregating traffic on a set of nodes and links with high traffic load level. Routing traffic on links and nodes that are already under utilization makes it possible for the links and nodes with no load to be set on sleep mode. The second approach is intended to dynamically route traffic through nodes and links with high traffic load level. Similar to the first approach, this approach computes a pair of paths for every newly arrived demand. It computes these paths for every new demand by comparing the power consumption of nodes and links in the network before the demand arrives with their potential power consumption if they are chosen along the paths of this demand. Simulations of two different networks were used to compare the total network power consumption obtained using the proposed techniques against a standard shared-path restoration scheme. Shared-path restoration is a network survivability method in which a link-disjoint backup path and wavelength is reserved at the time of call setup for a working path. However, in order to reduce spare capacity consumption, this reserved backup path and wavelength may be shared with other backup paths. Pool Sharing Scheme (PSS) is employed to implement shared-path restoration scheme [1]. In an optical network, the failure of a single link leads to the failure of all the lightpaths that pass through that particular link. PSS ensures that the amount of backup bandwidth required on a link to restore the failed connections will not be more than the total amount of reserved backup bandwidth on that link. Simulation results indicate that the proposed approaches lead to up to 35% power savings in WDM networks when traffic load is low. However, power saving decreases to 14% at high traffic load level. Furthermore, in terms of the total capacity consumption for working paths, PSS outperforms the two proposed approaches, as expected. In terms of total capacity consumption all the approaches behave similarly. In general, at low traffic load level, the two proposed approaches behave similar to PSS in terms of average link load, and the ratio of block demands. Nevertheless, at high traffic load, the proposed approaches result in higher ratio of blocked demands than PSS. They also lead to higher average link load than PSS for the equal number of generated demands.

  11. Data Sharing For Precision Medicine: Policy Lessons And Future Directions.

    PubMed

    Blasimme, Alessandro; Fadda, Marta; Schneider, Manuel; Vayena, Effy

    2018-05-01

    Data sharing is a precondition of precision medicine. Numerous organizations have produced abundant guidance on data sharing. Despite such efforts, data are not being shared to a degree that can trigger the expected data-driven revolution in precision medicine. We set out to explore why. Here we report the results of a comprehensive analysis of data-sharing guidelines issued over the past two decades by multiple organizations. We found that the guidelines overlap on a restricted set of policy themes. However, we observed substantial fragmentation in the policy landscape across specific organizations and data types. This may have contributed to the current stalemate in data sharing. To move toward a more efficient data-sharing ecosystem for precision medicine, policy makers should explore innovative ways to cope with central policy themes such as privacy, consent, and data quality; focus guidance on interoperability, attribution, and public engagement; and promote data-sharing policies that can be adapted to multiple data types.

  12. Building America Case Study: Impact of Improved Duct Insulation on Fixed-Capacity (SEER 13) and Variable-Capacity (SEER 22) Heat Pumps, Cocoa, Florida

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    C. Withers, J. Cummings, B. Nigusse, E. Martin

    A new generation of central, ducted variable-capacity heat pump systems has come on the market, promising very high cooling and heating efficiency. Instead of cycling on at full capacity and then cycling off when the thermostat is satisfied, they vary their cooling and heating output over a wide range (approximately 40 to 118% of nominal full capacity); thus, staying 'on' for 60% to 100% more hours per day compared to fixed-capacity systems. Current Phase 4 experiments in an instrumented lab home with simulated occupancy evaluate the impact of duct R-value enhancement on the overall operating efficiency of the variable-capacity systemmore » compared to the fixed-capacity system.« less

  13. On thinking and not being able to think: reflections on viewing the Abu Ghraib photos.

    PubMed

    Moss, Donald B

    2007-04-01

    Using experiences from childhood, from encounters with contemporary art, from clinical experience, and, most elaborately, from an initial viewing of the Abu Ghraib photos, the author argues that the interpretability of experience depends upon its being legible. This legibility, in turn, depends upon the interpreter maintaining contact with his/her own capacities for thought, and, more fundamentally, with the vitally necessary community of others with whom he/she shares those capacities.

  14. Shared-resource computing for small research labs.

    PubMed

    Ackerman, M J

    1982-04-01

    A real time laboratory computer network is described. This network is composed of four real-time laboratory minicomputers located in each of four division laboratories and a larger minicomputer in a centrally located computer room. Off the shelf hardware and software were used with no customization. The network is configured for resource sharing using DECnet communications software and the RSX-11-M multi-user real-time operating system. The cost effectiveness of the shared resource network and multiple real-time processing using priority scheduling is discussed. Examples of utilization within a medical research department are given.

  15. NASA Shared Services Center breaks ground

    NASA Image and Video Library

    2006-02-24

    NASA officials and elected leaders were on hand for the groundbreaking ceremony of the NASA Shared Services Center Feb. 24, 2006, on the grounds of Stennis Space Center. The NSSC provides agency centralized administrative processing, human resources, procurement and financial services. From left, Louisiana Economic Development Secretary Mike Olivier, Stennis Space Center Director Rick Gilbrech, Computer Sciences Corp. President Michael Laphen, NASA Deputy Administrator Shana Dale, Rep. Gene Taylor, Sen. Trent Lott, Mississippi Gov. Haley Barbour, NASA Administrator Mike Griffin and Shared Services Center Executive Director Arbuthnot use golden shovels to break ground at the site.

  16. NASA Shared Services Center breaks ground

    NASA Technical Reports Server (NTRS)

    2006-01-01

    NASA officials and elected leaders were on hand for the groundbreaking ceremony of the NASA Shared Services Center Feb. 24, 2006, on the grounds of Stennis Space Center. The NSSC provides agency centralized administrative processing, human resources, procurement and financial services. From left, Louisiana Economic Development Secretary Mike Olivier, Stennis Space Center Director Rick Gilbrech, Computer Sciences Corp. President Michael Laphen, NASA Deputy Administrator Shana Dale, Rep. Gene Taylor, Sen. Trent Lott, Mississippi Gov. Haley Barbour, NASA Administrator Mike Griffin and Shared Services Center Executive Director Arbuthnot use golden shovels to break ground at the site.

  17. A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research.

    PubMed

    Meeker, Daniella; Jiang, Xiaoqian; Matheny, Michael E; Farcas, Claudiu; D'Arcy, Michel; Pearlman, Laura; Nookala, Lavanya; Day, Michele E; Kim, Katherine K; Kim, Hyeoneui; Boxwala, Aziz; El-Kareh, Robert; Kuo, Grace M; Resnic, Frederic S; Kesselman, Carl; Ohno-Machado, Lucila

    2015-11-01

    Centralized and federated models for sharing data in research networks currently exist. To build multivariate data analysis for centralized networks, transfer of patient-level data to a central computation resource is necessary. The authors implemented distributed multivariate models for federated networks in which patient-level data is kept at each site and data exchange policies are managed in a study-centric manner. The objective was to implement infrastructure that supports the functionality of some existing research networks (e.g., cohort discovery, workflow management, and estimation of multivariate analytic models on centralized data) while adding additional important new features, such as algorithms for distributed iterative multivariate models, a graphical interface for multivariate model specification, synchronous and asynchronous response to network queries, investigator-initiated studies, and study-based control of staff, protocols, and data sharing policies. Based on the requirements gathered from statisticians, administrators, and investigators from multiple institutions, the authors developed infrastructure and tools to support multisite comparative effectiveness studies using web services for multivariate statistical estimation in the SCANNER federated network. The authors implemented massively parallel (map-reduce) computation methods and a new policy management system to enable each study initiated by network participants to define the ways in which data may be processed, managed, queried, and shared. The authors illustrated the use of these systems among institutions with highly different policies and operating under different state laws. Federated research networks need not limit distributed query functionality to count queries, cohort discovery, or independently estimated analytic models. Multivariate analyses can be efficiently and securely conducted without patient-level data transport, allowing institutions with strict local data storage requirements to participate in sophisticated analyses based on federated research networks. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association.

  18. Acción Mutua (Shared Action): a multipronged approach to delivering capacity-building assistance to agencies serving Latino communities in the United States.

    PubMed

    Ayala, George; Chión, Miguel; Díaz, Rafael M; Heckert, Andrea L; Nuño, Monica; del Pino, Homero E; Rodríguez, Claudia; Schroeder, Kurt; Smith, Terry

    2007-01-01

    Culturally appropriate, theory-based capacity-building assistance can serve a vital role in helping HIV prevention providers remain up-to-date, effective, and responsive to those they serve. Funded by the Centers for Disease Control and Prevention (CDC), AIDS Project Los Angeles, in collaboration with San Francisco State University's César E. Chávez Institute, conducted full-day site visits and qualitative interviews in 2005 with mid-level management staff of CDC-funded community-based organizations delivering HIV prevention services to Latino communities in the western region of the United States. We found that agencies we visited (1) had not yet adapted the evidence-based interventions they were using at the time of our visit and (2) requested technical assistance and training in the areas of program development, evaluation, group facilitation techniques, consumer recruitment, client retention, intervention adaptation, and materials development. Findings from this needs assessment were used to inform our seven-pronged approach to delivering capacity-building assistance entitled "Acción Mutua" (Shared Action). The approach emphasizes strategic partnerships, stakeholder involvement, organizational self-assessment, culturally appropriate materials development, interactive training, tailored onsite technical assistance, and professional networking opportunities. This article describes our approach in detail, the assessment process we used to develop it, and its implications for capacity-building practice.

  19. Institutional capacity for health systems research in East and Central African schools of public health: experiences with a capacity assessment tool.

    PubMed

    Jessani, Nasreen; Lewy, Daniela; Ekirapa-Kiracho, Elizabeth; Bennett, Sara

    2014-06-02

    Despite significant investments in health systems research (HSR) capacity development, there is a dearth of information regarding how to assess HSR capacity. An alliance of schools of public health (SPHs) in East and Central Africa developed a tool for the self-assessment of HSR capacity with the aim of producing institutional capacity development plans. Between June and November 2011, seven SPHs across the Democratic Republic of Congo, Ethiopia, Kenya, Rwanda, Tanzania, and Uganda implemented this co-created tool. The objectives of the institutional assessments were to assess existing capacities for HSR and to develop capacity development plans to address prioritized gaps. A mixed-method approach was employed consisting of document analysis, self-assessment questionnaires, in-depth interviews, and institutional dialogues aimed at capturing individual perceptions of institutional leadership, collective HSR skills, knowledge translation, and faculty incentives to engage in HSR. Implementation strategies for the capacity assessment varied across the SPHs. This paper reports findings from semi-structured interviews with focal persons from each SPH, to reflect on the process used at each SPH to execute the institutional assessments as well as the perceived strengths and weaknesses of the assessment process. The assessment tool was robust enough to be utilized in its entirety across all seven SPHs resulting in a thorough HSR capacity assessment and a capacity development plan for each SPH. Successful implementation of the capacity assessment exercises depended on four factors: (i) support from senior leadership and collaborators, (ii) a common understanding of HSR, (iii) adequate human and financial resources for the exercise, and (iv) availability of data. Methods of extracting information from the results of the assessments, however, were tailored to the unique objectives of each SPH. This institutional HSR capacity assessment tool and the process for its utilization may be valuable for any SPH. The self-assessments, as well as interviews with external stakeholders, provided diverse sources of input and galvanized interest around HSR at multiple levels.

  20. Network Analysis of an Emergent Massively Collaborative Creation on Video Sharing Website

    NASA Astrophysics Data System (ADS)

    Hamasaki, Masahiro; Takeda, Hideaki; Nishimura, Takuichi

    The Web technology enables numerous people to collaborate in creation. We designate it as massively collaborative creation via the Web. As an example of massively collaborative creation, we particularly examine video development on Nico Nico Douga, which is a video sharing website that is popular in Japan. We specifically examine videos on Hatsune Miku, a version of a singing synthesizer application software that has inspired not only song creation but also songwriting, illustration, and video editing. As described herein, creators of interact to create new contents through their social network. In this paper, we analyzed the process of developing thousands of videos based on creators' social networks and investigate relationships among creation activity and social networks. The social network reveals interesting features. Creators generate large and sparse social networks including some centralized communities, and such centralized community's members shared special tags. Different categories of creators have different roles in evolving the network, e.g., songwriters gather more links than other categories, implying that they are triggers to network evolution.

  1. 32 CFR 1904.3 - Procedures governing acceptance of service of process.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... INTELLIGENCE AGENCY PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1904.3 Procedures governing... addressed as follows: Litigation Division, Office of General Counsel, Central Intelligence Agency... Director and Deputy Director of Central Intelligence—in his or her individual capacity. (3) Mail Service...

  2. 32 CFR 1904.3 - Procedures governing acceptance of service of process.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... INTELLIGENCE AGENCY PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1904.3 Procedures governing... addressed as follows: Litigation Division, Office of General Counsel, Central Intelligence Agency... Director and Deputy Director of Central Intelligence—in his or her individual capacity. (3) Mail Service...

  3. 32 CFR 1904.3 - Procedures governing acceptance of service of process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... INTELLIGENCE AGENCY PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1904.3 Procedures governing... addressed as follows: Litigation Division, Office of General Counsel, Central Intelligence Agency... Director and Deputy Director of Central Intelligence—in his or her individual capacity. (3) Mail Service...

  4. 32 CFR 1904.3 - Procedures governing acceptance of service of process.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... INTELLIGENCE AGENCY PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1904.3 Procedures governing... addressed as follows: Litigation Division, Office of General Counsel, Central Intelligence Agency... Director and Deputy Director of Central Intelligence—in his or her individual capacity. (3) Mail Service...

  5. 32 CFR 1904.3 - Procedures governing acceptance of service of process.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INTELLIGENCE AGENCY PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1904.3 Procedures governing... addressed as follows: Litigation Division, Office of General Counsel, Central Intelligence Agency... Director and Deputy Director of Central Intelligence—in his or her individual capacity. (3) Mail Service...

  6. 77 FR 796 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-06

    ... fiduciary capacity, 9.75 percent of the outstanding voting shares of Mechanics Financial Corporation, and thereby retain Mechanics Savings Bank, both in Mansfield, Ohio. B. Federal Reserve Bank of Kansas City...

  7. Building team adaptive capacity: the roles of sensegiving and team composition.

    PubMed

    Randall, Kenneth R; Resick, Christian J; DeChurch, Leslie A

    2011-05-01

    The current study draws on motivated information processing in groups theory to propose that leadership functions and composition characteristics provide teams with the epistemic and social motivation needed for collective information processing and strategy adaptation. Three-person teams performed a city management decision-making simulation (N=74 teams; 222 individuals). Teams first managed a simulated city that was newly formed and required growth strategies and were then abruptly switched to a second simulated city that was established and required revitalization strategies. Consistent with hypotheses, external sensegiving and team composition enabled distinct aspects of collective information processing. Sensegiving prompted the emergence of team strategy mental models (i.e., cognitive information processing); psychological collectivism facilitated information sharing (i.e., behavioral information processing); and cognitive ability provided the capacity for both the cognitive and behavioral aspects of collective information processing. In turn, team mental models and information sharing enabled reactive strategy adaptation.

  8. Mental time travel and the shaping of the human mind

    PubMed Central

    Suddendorf, Thomas; Addis, Donna Rose; Corballis, Michael C.

    2009-01-01

    Episodic memory, enabling conscious recollection of past episodes, can be distinguished from semantic memory, which stores enduring facts about the world. Episodic memory shares a core neural network with the simulation of future episodes, enabling mental time travel into both the past and the future. The notion that there might be something distinctly human about mental time travel has provoked ingenious attempts to demonstrate episodic memory or future simulation in non-human animals, but we argue that they have not yet established a capacity comparable to the human faculty. The evolution of the capacity to simulate possible future events, based on episodic memory, enhanced fitness by enabling action in preparation of different possible scenarios that increased present or future survival and reproduction chances. Human language may have evolved in the first instance for the sharing of past and planned future events, and, indeed, fictional ones, further enhancing fitness in social settings. PMID:19528013

  9. KENNEDY SPACE CENTER, FLA. - NASA officials and government representatives are gathered to learn about the assets of the Central Florida Research Park, near Orlando. At the far end of the table is NASA Administrator Sean O’Keefe. He is flanked, on the left, by Florida Congressman Tom Feeney and U.S. Senator Bill Nelson; and on the right by U.S. Congressman Dave Weldon. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA officials and government representatives are gathered to learn about the assets of the Central Florida Research Park, near Orlando. At the far end of the table is NASA Administrator Sean O’Keefe. He is flanked, on the left, by Florida Congressman Tom Feeney and U.S. Senator Bill Nelson; and on the right by U.S. Congressman Dave Weldon. Central Florida leaders are proposing the research park as the site for the NASA Shared Services Center. The center would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  10. Building Cross-Country Networks for Laboratory Capacity and Improvement.

    PubMed

    Schneidman, Miriam; Matu, Martin; Nkengasong, John; Githui, Willie; Kalyesubula-Kibuuka, Simeon; Silva, Kelly Araujo

    2018-03-01

    Laboratory networks are vital to well-functioning public health systems and disease control efforts. Cross-country laboratory networks play a critical role in supporting epidemiologic surveillance, accelerating disease outbreak response, and tracking drug resistance. The East Africa Public Health Laboratory Network was established to bolster diagnostic and disease surveillance capacity. The network supports the introduction of regional quality standards; facilitates the rollout and evaluation of new diagnostic tools; and serves as a platform for training, research, and knowledge sharing. Participating facilities benefitted from state-of-the art investments, capacity building, and mentorship; conducted multicountry research studies; and contributed to disease outbreak response. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Sharing Data in the Global Ocean Observing System (Invited)

    NASA Astrophysics Data System (ADS)

    Lindstrom, E. J.; McCurdy, A.; Young, J.; Fischer, A. S.

    2010-12-01

    We examine the evolution of data sharing in the field of physical oceanography to highlight the challenges now before us. Synoptic global observation of the ocean from space and in situ platforms has significantly matured over the last two decades. In the early 1990’s the community data sharing challenges facing the World Ocean Circulation Experiment (WOCE) largely focused on the behavior of individual scientists. Satellite data sharing depended on the policy of individual agencies. Global data sets were delivered with considerable delay and with enormous personal sacrifice. In the 2000’s the requirements for global data sets and sustained observations from the likes of the U.N. Framework Convention on Climate Change have led to data sharing and cooperation at a grander level. It is more effective and certainly more efficient. The Joint WMO/IOC Technical Commission on Oceanography and Marine Meteorology (JCOMM) provided the means to organize many aspects of data collection and data dissemination globally, for the common good. In response the Committee on Earth Observing Satellites organized Virtual Constellations to enable the assembly and sharing of like kinds of satellite data (e.g., sea surface topography, ocean vector winds, and ocean color). Individuals in physical oceanography have largely adapted to the new rigors of sharing data for the common good, and as a result of this revolution new science has been enabled. Primary obstacles to sharing have shifted from the individual level to the national level. As we enter into the 2010’s the demands for ocean data continue to evolve with an expanded requirement for more real-time reporting and broader disciplinary coverage, to answer key scientific and societal questions. We are also seeing the development of more numerous national contributions to the global observing system. The drivers for the establishment of global ocean observing systems are expanding beyond climate to include biological and biogeochemical issues (e.g. biodiversity and ecosystem services, fisheries collapse, and ocean acidification). This expanded suite of demands and drivers challenge us further to share data for the common good across specialties. This requires that more ocean scientific communities and national ocean observing programs move towards maturity in terms of global data collection capability, sharing capacity, and data management standards. In oceanography the time has arrived for a cultural shift toward more shared collective observing capabilities. Necessarily we must also rapidly move toward harmony in national data sharing policies for the ocean environment. Building capacity to share ocean observations has been an objective for decades and has resulted in an expanded understanding of technologies and management policies that foster data sharing and provenance tracking.

  12. Implementing Health Impact Assessment Programs in State Health Agencies: Lessons Learned From Pilot Programs, 2009-2011.

    PubMed

    Goff, Nancy; Wyss, Kerry; Wendel, Arthur; Jarris, Paul

    2016-01-01

    Health Impact Assessment (HIA) has emerged as a promising tool to integrate health considerations into decision making. The growth and success of HIA practice in the United States will be dependent on building the capacity of practitioners. This article seeks to identify the role of state health agencies (SHAs) in building capacity for conducting HIAs and the key components of initiatives that produced effective HIAs and HIA programs. The authors proposed to answer 3 research questions: (1) What can be the role of the SHA in HIA? (2) What are the characteristics of successful state HIA programs? and (3) What are some effective strategies for building capacity for HIA in SHAs and local health departments? The authors reviewed program reports from the ASTHO's pilot state health agencies (California, Minnesota, Oregon, and Wisconsin) that, between 2009 and 2011, created HIA programs to provide HIA training, conduct HIAs, and build practitioner networks. Program reports were examined for shared themes on the role of SHAs in a statewide HIA initiative, the characteristics of successful programs, and effective strategies for building capacity. Despite differences among the programs, many shared themes existed. These include stressing the importance of a basic, sustained infrastructure for HIA practice; leveraging existing programs and networks; and working in partnership with diverse stakeholders. SHAs can build capacity for HIA, and SHAs can both lead and support the completion of individual HIAs. States and territories interested in starting comprehensive statewide HIA initiatives could consider implementing the strategies identified by the pilot programs.

  13. The Role of Gender in the Crisis at Central High, 1957.

    ERIC Educational Resources Information Center

    Butler, Judy D.

    This paper examines the role of women in the 1957 desegregation of Arkansas's Central High School, using data from interviews with black and white teachers and other prominent community members at the time. The paper shares stories of teachers, students, the Mother's League, the Women's Emergency Community, and Daisy Bates, president of the…

  14. Making STEM Fun: How to Organize a STEM Camp

    ERIC Educational Resources Information Center

    Davis, Kimberly E. Bryant; Hardin, Stacey E.

    2013-01-01

    The work from the University of Central Florida's STEM summer camp (sponsored by Workforce Central Florida) is shared. The camps targeted low-SES schools with a high percentage of students on free and reduced lunch as well as high percentages of students with. Students were given preassessments and postassessments to gauge their knowledge of and…

  15. Gulf of Fonseca, Pacifica coast of Central America as seen from Apollo 9

    NASA Image and Video Library

    1969-03-12

    AS09-19-3019 (3-13 March 1969) --- Gulf of Fonseca, on the Pacific coast of Central America, as photographed from the Apollo 9 spacecraft during its Earth-orbital mission. The gulf is shared by the nations of El Salvador, Honduras, and Nicaragua. The prominent volcano on the peninsula in Nicaragua is Volcan Cosiguina.

  16. GECKO: a complete large-scale gene expression analysis platform.

    PubMed

    Theilhaber, Joachim; Ulyanov, Anatoly; Malanthara, Anish; Cole, Jack; Xu, Dapeng; Nahf, Robert; Heuer, Michael; Brockel, Christoph; Bushnell, Steven

    2004-12-10

    Gecko (Gene Expression: Computation and Knowledge Organization) is a complete, high-capacity centralized gene expression analysis system, developed in response to the needs of a distributed user community. Based on a client-server architecture, with a centralized repository of typically many tens of thousands of Affymetrix scans, Gecko includes automatic processing pipelines for uploading data from remote sites, a data base, a computational engine implementing approximately 50 different analysis tools, and a client application. Among available analysis tools are clustering methods, principal component analysis, supervised classification including feature selection and cross-validation, multi-factorial ANOVA, statistical contrast calculations, and various post-processing tools for extracting data at given error rates or significance levels. On account of its open architecture, Gecko also allows for the integration of new algorithms. The Gecko framework is very general: non-Affymetrix and non-gene expression data can be analyzed as well. A unique feature of the Gecko architecture is the concept of the Analysis Tree (actually, a directed acyclic graph), in which all successive results in ongoing analyses are saved. This approach has proven invaluable in allowing a large (approximately 100 users) and distributed community to share results, and to repeatedly return over a span of years to older and potentially very complex analyses of gene expression data. The Gecko system is being made publicly available as free software http://sourceforge.net/projects/geckoe. In totality or in parts, the Gecko framework should prove useful to users and system developers with a broad range of analysis needs.

  17. A link between LEAFY and B-gene homologues in Welwitschia mirabilis sheds light on ancestral mechanisms prefiguring floral development.

    PubMed

    Moyroud, Edwige; Monniaux, Marie; Thévenon, Emmanuel; Dumas, Renaud; Scutt, Charles P; Frohlich, Michael W; Parcy, François

    2017-10-01

    Flowering plants evolved from an unidentified gymnosperm ancestor. Comparison of the mechanisms controlling development in angiosperm flowers and gymnosperm cones may help to elucidate the mysterious origin of the flower. We combined gene expression studies with protein behaviour characterization in Welwitschia mirabilis to test whether the known regulatory links between LEAFY and its MADS-box gene targets, central to flower development, might also contribute to gymnosperm reproductive development. We found that WelLFY, one of two LEAFY-like genes in Welwitschia, could be an upstream regulator of the MADS-box genes APETALA3/PISTILLATA-like (B-genes). We demonstrated that, even though their DNA-binding domains are extremely similar, WelLFY and its paralogue WelNDLY exhibit distinct DNA-binding specificities, and that, unlike WelNDLY, WelLFY shares with its angiosperm orthologue the capacity to bind promoters of Welwitschia B-genes. Finally, we identified several cis-elements mediating these interactions in Welwitschia and obtained evidence that the link between LFY homologues and B-genes is also conserved in two other gymnosperms, Pinus and Picea. Although functional approaches to investigate cone development in gymnosperms are limited, our state-of-the-art biophysical techniques, coupled with expression studies, provide evidence that crucial links, central to the control of floral development, may already have existed before the appearance of flowers. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  18. Using Secure Web Services to Visualize Poison Center Data for Nationwide Biosurveillance: A Case Study

    PubMed Central

    Savel, Thomas G; Bronstein, Alvin; Duck, William; Rhodes, M. Barry; Lee, Brian; Stinn, John; Worthen, Katherine

    2010-01-01

    Objectives Real-time surveillance systems are valuable for timely response to public health emergencies. It has been challenging to leverage existing surveillance systems in state and local communities, and, using a centralized architecture, add new data sources and analytical capacity. Because this centralized model has proven to be difficult to maintain and enhance, the US Centers for Disease Control and Prevention (CDC) has been examining the ability to use a federated model based on secure web services architecture, with data stewardship remaining with the data provider. Methods As a case study for this approach, the American Association of Poison Control Centers and the CDC extended an existing data warehouse via a secure web service, and shared aggregate clinical effects and case counts data by geographic region and time period. To visualize these data, CDC developed a web browser-based interface, Quicksilver, which leveraged the Google Maps API and Flot, a javascript plotting library. Results Two iterations of the NPDS web service were completed in 12 weeks. The visualization client, Quicksilver, was developed in four months. Discussion This implementation of web services combined with a visualization client represents incremental positive progress in transitioning national data sources like BioSense and NPDS to a federated data exchange model. Conclusion Quicksilver effectively demonstrates how the use of secure web services in conjunction with a lightweight, rapidly deployed visualization client can easily integrate isolated data sources for biosurveillance. PMID:23569581

  19. Proteomics and comparative genomics of Nitrososphaera viennensis reveal the core genome and adaptations of archaeal ammonia oxidizers

    PubMed Central

    Kerou, Melina; Offre, Pierre; Valledor, Luis; Abby, Sophie S.; Melcher, Michael; Nagler, Matthias; Weckwerth, Wolfram; Schleper, Christa

    2016-01-01

    Ammonia-oxidizing archaea (AOA) are among the most abundant microorganisms and key players in the global nitrogen and carbon cycles. They share a common energy metabolism but represent a heterogeneous group with respect to their environmental distribution and adaptions, growth requirements, and genome contents. We report here the genome and proteome of Nitrososphaera viennensis EN76, the type species of the archaeal class Nitrososphaeria of the phylum Thaumarchaeota encompassing all known AOA. N. viennensis is a soil organism with a 2.52-Mb genome and 3,123 predicted protein-coding genes. Proteomic analysis revealed that nearly 50% of the predicted genes were translated under standard laboratory growth conditions. Comparison with genomes of closely related species of the predominantly terrestrial Nitrososphaerales as well as the more streamlined marine Nitrosopumilales [Candidatus (Ca.) order] and the acidophile “Ca. Nitrosotalea devanaterra” revealed a core genome of AOA comprising 860 genes, which allowed for the reconstruction of central metabolic pathways common to all known AOA and expressed in the N. viennensis and “Ca. Nitrosopelagicus brevis” proteomes. Concomitantly, we were able to identify candidate proteins for as yet unidentified crucial steps in central metabolisms. In addition to unraveling aspects of core AOA metabolism, we identified specific metabolic innovations associated with the Nitrososphaerales mediating growth and survival in the soil milieu, including the capacity for biofilm formation, cell surface modifications and cell adhesion, and carbohydrate conversions as well as detoxification of aromatic compounds and drugs. PMID:27864514

  20. Static Memory Deduplication for Performance Optimization in Cloud Computing.

    PubMed

    Jia, Gangyong; Han, Guangjie; Wang, Hao; Yang, Xuan

    2017-04-27

    In a cloud computing environment, the number of virtual machines (VMs) on a single physical server and the number of applications running on each VM are continuously growing. This has led to an enormous increase in the demand of memory capacity and subsequent increase in the energy consumption in the cloud. Lack of enough memory has become a major bottleneck for scalability and performance of virtualization interfaces in cloud computing. To address this problem, memory deduplication techniques which reduce memory demand through page sharing are being adopted. However, such techniques suffer from overheads in terms of number of online comparisons required for the memory deduplication. In this paper, we propose a static memory deduplication (SMD) technique which can reduce memory capacity requirement and provide performance optimization in cloud computing. The main innovation of SMD is that the process of page detection is performed offline, thus potentially reducing the performance cost, especially in terms of response time. In SMD, page comparisons are restricted to the code segment, which has the highest shared content. Our experimental results show that SMD efficiently reduces memory capacity requirement and improves performance. We demonstrate that, compared to other approaches, the cost in terms of the response time is negligible.

  1. Static Memory Deduplication for Performance Optimization in Cloud Computing

    PubMed Central

    Jia, Gangyong; Han, Guangjie; Wang, Hao; Yang, Xuan

    2017-01-01

    In a cloud computing environment, the number of virtual machines (VMs) on a single physical server and the number of applications running on each VM are continuously growing. This has led to an enormous increase in the demand of memory capacity and subsequent increase in the energy consumption in the cloud. Lack of enough memory has become a major bottleneck for scalability and performance of virtualization interfaces in cloud computing. To address this problem, memory deduplication techniques which reduce memory demand through page sharing are being adopted. However, such techniques suffer from overheads in terms of number of online comparisons required for the memory deduplication. In this paper, we propose a static memory deduplication (SMD) technique which can reduce memory capacity requirement and provide performance optimization in cloud computing. The main innovation of SMD is that the process of page detection is performed offline, thus potentially reducing the performance cost, especially in terms of response time. In SMD, page comparisons are restricted to the code segment, which has the highest shared content. Our experimental results show that SMD efficiently reduces memory capacity requirement and improves performance. We demonstrate that, compared to other approaches, the cost in terms of the response time is negligible. PMID:28448434

  2. Criminal Use of Assault Weapons and High-Capacity Semiautomatic Firearms: an Updated Examination of Local and National Sources.

    PubMed

    Koper, Christopher S; Johnson, William D; Nichols, Jordan L; Ayers, Ambrozine; Mullins, Natalie

    2018-06-01

    Policies restricting semiautomatic assault weapons and large-capacity ammunition magazines are intended to reduce gunshot victimizations by limiting the stock of semiautomatic firearms with large ammunition capacities and other military-style features conducive to criminal use. The federal government banned such weaponry from 1994 to 2004, and a few states currently impose similar restrictions. Recent debates concerning these weapons have highlighted their use in mass shootings, but there has been little examination of their use in gun crime more generally since the expiration of the federal ban. This study investigates current levels of criminal activity with assault weapons and other high-capacity semiautomatics in the USA using several local and national data sources including the following: (1) guns recovered by police in ten large cities, (2) guns reported by police to federal authorities for investigative tracing, (3) guns used in murders of police, and (4) guns used in mass murders. Results suggest assault weapons (primarily assault-type rifles) account for 2-12% of guns used in crime in general (most estimates suggest less than 7%) and 13-16% of guns used in murders of police. Assault weapons and other high-capacity semiautomatics together generally account for 22 to 36% of crime guns, with some estimates upwards of 40% for cases involving serious violence including murders of police. Assault weapons and other high-capacity semiautomatics appear to be used in a higher share of firearm mass murders (up to 57% in total), though data on this issue are very limited. Trend analyses also indicate that high-capacity semiautomatics have grown from 33 to 112% as a share of crime guns since the expiration of the federal ban-a trend that has coincided with recent growth in shootings nationwide. Further research seems warranted on how these weapons affect injuries and deaths from gun violence and how their regulation may impact public health.

  3. Preliminary Findings of the South Africa Power System Capacity Expansion and Operational Modelling Study: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reber, Timothy J; Chartan, Erol Kevin; Brinkman, Gregory L

    Wind and solar power contract prices have recently become cheaper than many conventional new-build alternatives in South Africa and trends suggest a continued increase in the share of variable renewable energy (vRE) on South Africa's power system with coal technology seeing the greatest reduction in capacity, see 'Figure 6: Percentage share by Installed Capacity (MW)' in [1]. Hence it is essential to perform a state-of-the-art grid integration study examining the effects of these high penetrations of vRE on South Africa's power system. Under the 21st Century Power Partnership (21CPP), funded by the U.S. Department of Energy, the National Renewable Energymore » Laboratory (NREL) has significantly augmented existing models of the South African power system to investigate future vRE scenarios. NREL, in collaboration with Eskom's Planning Department, further developed, tested and ran a combined capacity expansion and operational model of the South African power system including spatially disaggregated detail and geographical representation of system resources. New software to visualize and interpret modelling outputs has been developed, and scenario analysis of stepwise vRE build targets reveals new insight into associated planning and operational impacts and costs. The model, built using PLEXOS, is split into two components, firstly a capacity expansion model and secondly a unit commitment and economic dispatch model. The capacity expansion model optimizes new generation decisions to achieve the lowest cost, with a full understanding of capital cost and an approximated understanding of operational costs. The operational model has a greater set of detailed operational constraints and is run at daily resolutions. Both are run from 2017 through 2050. This investigation suggests that running both models in tandem may be the most effective means to plan the least cost South African power system as build plans seen to be more expensive than optimal by the capacity expansion model can produce greater operational cost savings seen only in the operational model.« less

  4. JPRS Report, East Europe

    DTIC Science & Technology

    1987-12-03

    is also surprising in the film and television industry . It often happens that Slovak actors play in our films and always speak Czech badly (with...Metallurgical Pro- cessing Industry in Liberec, the Tesla in Holesovice, the Bytex in Liberec, the Plastika in Nitra, the First of May Rubber Plants in...Presov. [Question] Could you describe their share in our national economy? [Answer] In the centrally managed industry these orga- nizations share

  5. Report to Congress on the Strategic Defense Initiative, 1992

    DTIC Science & Technology

    1992-07-01

    1.4.3 Shared View on Defenses .............................................................. 1-6 1.5 U.S. Contribution to a Global Defense System...including, in our view , that such defenses would not threaten existing deterrents--and the willingness of the U.S. to extend protection to allies...representing the central government as well as several Republics, the presentation was positively received. 1.4.3 Shared View on Defenses President

  6. Bermuda 2.0: reflections from Santa Cruz

    PubMed Central

    Reardon, Jenny; Ankeny, Rachel A.; Bangham, Jenny; W. Darling, Katherine; Hilgartner, Stephen; Jones, Kathryn Maxson; Shapiro, Beth; Stevens, Hallam

    2016-01-01

    Abstract In February 1996, the genome community met in Bermuda to formulate principles for circulating genomic data. Although it is now 20 years since the Bermuda Principles were formulated, they continue to play a central role in shaping genomic and data-sharing practices. However, since 1996, “openness” has become an increasingly complex issue. This commentary seeks to articulate three core challenges data-sharing faces today. PMID:28369360

  7. KSC-04pd0270

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - After a presentation about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center, Congressmen Tom Feeney (center) and Dave Weldon (right) share a humorous moment with NASA Administrator Sean O’Keefe (foreground). Six sites around the U.S. are under consideration for location of the Center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Others attending the presentation included Congressman Dave Weldon, U.S. Representative Ric Keller, Center Director Jim Kennedy and Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida.

  8. High-Dimensional Circular Quantum Secret Sharing Using Orbital Angular Momentum

    NASA Astrophysics Data System (ADS)

    Tang, Dawei; Wang, Tie-jun; Mi, Sichen; Geng, Xiao-Meng; Wang, Chuan

    2016-11-01

    Quantum secret sharing is to distribute secret message securely between multi-parties. Here exploiting orbital angular momentum (OAM) state of single photons as the information carrier, we propose a high-dimensional circular quantum secret sharing protocol which increases the channel capacity largely. In the proposed protocol, the secret message is split into two parts, and each encoded on the OAM state of single photons. The security of the protocol is guaranteed by the laws of non-cloning theorem. And the secret messages could not be recovered except that the two receivers collaborated with each other. Moreover, the proposed protocol could be extended into high-level quantum systems, and the enhanced security could be achieved.

  9. Study of car-sharing diffusion criticality conditions based on human traveling network

    NASA Astrophysics Data System (ADS)

    Xu, Yan; Ji, Xuehong

    Car-sharing program, like Car2go, is an innovative urban transportation mode where the car-sharing company provides a car fleet to offer people with the short-term access of car traveling. As a new traveling service, car-sharing platforms have been struggling hard to trigger initial users and speed up their diffusion process. Unlike new product spreading via geographical proximity people, car-sharing users usually drive sharing cars to different destinations and influence people there, and potential user decision also depends on previous user activity at all their destinations. Car-sharing user connections are mainly affected by their traveling behaviors. The influence of user traveling network on new service/product spreading process has been rarely studied before. Here, we find that the infective rate between users with the same destination is critical to the minimum user base of car-sharing diffusion. Moreover, a city with central user network is more appropriate for car-sharing. It leads to a small critical infective rate for diffusion, and a large stable market size of car-sharing service. Our study can impact car-sharing market strategies ranging from market expansion in one city to optimal market selection among different cities.

  10. Experience facilitates the emergence of sharing behavior among 7.5-month-old infants

    PubMed Central

    Xu, Jing; Saether, Lucie; Sommerville, Jessica A.

    2016-01-01

    Given the centrality of prosociality in everyday social functioning, understanding the factors and mechanisms underlying the origins of prosocial development is of critical importance. This experiment investigated whether experience with reciprocal object exchanges can drive the developmental onset of sharing behavior. Seven-month-old infants took part in two laboratory visits to assess their sharing behavior and ability to release objects. During the intervening 7 −14 day period parents led infants in an intervention in which they were either encouraged to release objects into a container (bucket condition, n = 20), or share objects with the parent in the context of reciprocal object exchanges (sharing condition, n = 20). Results showed that infants in the sharing condition shared significantly more than infants in the bucket condition following the intervention, and infants in the sharing condition significantly increased their sharing behavior across the two visits. Parental empathy moderated the effect of this sharing intervention, but frequency of practice did not. These results suggest that reciprocal turn-taking in dyadic object-exchange interactions may facilitate the early emergence of sharing behavior, and this effect is mediated by parental empathy. PMID:27657650

  11. Rural Labour in Latin America.

    ERIC Educational Resources Information Center

    de Janvry, Alain; And Others

    1989-01-01

    Discusses the status of rural labor and the performance of labor markets in Latin American agriculture. Points out the rapidly declining share of agriculture in the total labor force, weak capacity for creating nonagricultural employment, and rapidly increasing migration to towns. (JOW)

  12. Wellhead power production with a rotary separator turbine (RP 1196)

    NASA Astrophysics Data System (ADS)

    Cerini, D. J.; Record, J.

    1982-12-01

    A rotary-separator turbine was built with full flow capacity for a 500 F downhole temperature with a 850,000 lbm/hr production rate. The test system and results obtained in field tests are described. The preliminary design of a 10-megawatt wellhead power plant for the Roosevelt type resource is described. This system shows a specific power of .0013 kW hr per lbm, which is 20 percent greater than an optimized wellhead single stage flash plant. This is 26 percent greater than a central plant of 20 to 50 MW capacity when consideration is given to steam-gathering system pressure drop between the wells and central plant.

  13. KSC-04PD-0249

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. NASA Administrator Sean OKeefe (right) greets Florida Congressman Tom Feeney during a tour of the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  14. KSC-04PD-0252

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. NASA Administrator Sean OKeefe (left) greets U.S. Representative Ric Keller during a tour of the Central Florida Research Park, near Orlando. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  15. 28 CFR 0.75 - Policy functions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., automated information services, publication services, library services and any other Department-wide central...) Provide computer and digital telecommunications services on an equitable resource-sharing basis to all...

  16. 28 CFR 0.75 - Policy functions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., automated information services, publication services, library services and any other Department-wide central...) Provide computer and digital telecommunications services on an equitable resource-sharing basis to all...

  17. Sovereignty Under Siege: Drug Trafficking and State Capacity in the Caribbean and Central America

    DTIC Science & Technology

    2016-06-01

    CARIBBEAN AND CENTRAL AMERICA 5. FUNDING NUMBERS 6. AUTHOR(S) Ryan Thomas King 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval...Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME(S) AND ADDRESS(ES) N/A...trafficking organizations have increased their prominence throughout the Caribbean and Central America. These organizations undermine the rule of law

  18. 16 CFR 305.12 - Labeling for central air conditioners, heat pumps, and furnaces.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... pumps, and furnaces. (a) Layout. All energy labels for central air conditioners, heat pumps, and... the end of this part illustrating the basic layout. All positioning, spacing, type sizes, and line... calculated for heating Region IV for the standardized design heating requirement nearest the capacity...

  19. 16 CFR 305.12 - Labeling for central air conditioners, heat pumps, and furnaces.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... pumps, and furnaces. (a) Layout. All energy labels for central air conditioners, heat pumps, and... the end of this part illustrating the basic layout. All positioning, spacing, type sizes, and line... calculated for heating Region IV for the standardized design heating requirement nearest the capacity...

  20. 16 CFR 305.12 - Labeling for central air conditioners, heat pumps, and furnaces.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... pumps, and furnaces. (a) Layout. All energy labels for central air conditioners, heat pumps, and... end of this part illustrating the basic layout. All positioning, spacing, type sizes, and line widths... calculated for heating Region IV for the standardized design heating requirement nearest the capacity...

  1. 16 CFR 305.12 - Labeling for central air conditioners, heat pumps, and furnaces.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... pumps, and furnaces. (a) Layout. All energy labels for central air conditioners, heat pumps, and... the end of this part illustrating the basic layout. All positioning, spacing, type sizes, and line... calculated for heating Region IV for the standardized design heating requirement nearest the capacity...

  2. 75 FR 40802 - Southern Star Central Gas Pipeline, Inc.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP10-2-001] Southern Star... Star Central Gas Pipeline, Inc. (Southern Star), 4700 Highway 56, Owensboro, Kentucky 42301, filed in... CP10-2-000. Specifically, Southern Star proposes to increase the working gas capacity and amend the...

  3. Absorptive Capacity: A Conceptual Framework for Understanding District Central Office Learning

    ERIC Educational Resources Information Center

    Farrell, Caitlin C.; Coburn, Cynthia E.

    2017-01-01

    Globally, school systems are pressed to engage in large-scale school improvement. In the United States and other countries, school district central offices and other local governing agencies often engage with external organizations and individuals to support such educational change efforts. However, initiatives with external partners are not…

  4. "Islands of Decency": Building Capacity in a Sea of Despair

    ERIC Educational Resources Information Center

    Abu El-Haj, Thea Renda

    2013-01-01

    This response focuses attention on three key issues raised by Brayboy's talk: training our analyses on the impact of neoliberal policies reshaping schools and societies, developing an engaged anthropology of education to build local capacity, and remembering the centrality of our relationships in the midst of this work. (Contains 3 notes.)

  5. Value of Coaching in Building Leadership Capacity of Principals in Urban Schools

    ERIC Educational Resources Information Center

    Farver, Anita R.; Holt, Carleton R.

    2015-01-01

    The purpose of this qualitative case study was to understand how coaching support structures enabled and sustained leadership practices of urban principals. The study investigated how the intervention of coaching for academic leaders can serve as evidence-based professional development for building leadership capacity. The central focus was on…

  6. An Estimation of the Potential Utilization in Iranian Pharmaceutical Industry Involved in the Stock Exchange, 2008-2012.

    PubMed

    Annabi, Majid; Kebriaeezadeh, Abbas; Mohammadi, Timor; Marashi Shoshtari, Seyed Nasrolah; Abedin Dorkoosh, Farid; Pourreza, Abolghasem; Heydari, Hassan

    2017-01-01

    The aim of this study was to measure the potential of production and the capacity used in the pharmaceutical industry. Capacity use is the actual production rate to the potential output, which reflects the gap between actual production and production capacity . Through econometric methods, translog cost function in the short run along with functions of share cost of production factors is estimated through seemingly unrelated repeated regression (SURE) as a multivariate regression analysis provided by zeller. During the study the capacity used is decreasing. The capacity used, which calculated by weighted average, also decreased and the amount during the study period is much less than the simple average of the industry. Average capacity utilization in the industry over five years of study is equal to 57% while the average capacity used calculated by the weighted of industry average is 37%. To enhance the economic potential requires a proper use of resources, creation of favorable economic structure and productivity of the industry. Due to the large amount of unused capacity in the pharmaceutical industry there is no need to invest anymore unless in new grounds and it is obvious that more investment will change using capacity.

  7. An Estimation of the Potential Utilization in Iranian Pharmaceutical Industry Involved in the Stock Exchange, 2008-2012

    PubMed Central

    Annabi, Majid; Kebriaeezadeh, Abbas; Mohammadi, Timor; Marashi Shoshtari, Seyed Nasrolah; Abedin Dorkoosh, Farid; Pourreza, Abolghasem; Heydari, Hassan

    2017-01-01

    The aim of this study was to measure the potential of production and the capacity used in the pharmaceutical industry. Capacity use is the actual production rate to the potential output, which reflects the gap between actual production and production capacity. Through econometric methods, translog cost function in the short run along with functions of share cost of production factors is estimated through seemingly unrelated repeated regression (SURE) as a multivariate regression analysis provided by zeller. During the study the capacity used is decreasing. The capacity used, which calculated by weighted average, also decreased and the amount during the study period is much less than the simple average of the industry. Average capacity utilization in the industry over five years of study is equal to 57% while the average capacity used calculated by the weighted of industry average is 37%. To enhance the economic potential requires a proper use of resources, creation of favorable economic structure and productivity of the industry. Due to the large amount of unused capacity in the pharmaceutical industry there is no need to invest anymore unless in new grounds and it is obvious that more investment will change using capacity. PMID:29552074

  8. Involving Research Stakeholders in Developing Policy on Sharing Public Health Research Data in Kenya

    PubMed Central

    Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy

    2015-01-01

    Increased global sharing of public health research data has potential to advance scientific progress but may present challenges to the interests of research stakeholders, particularly in low-to-middle income countries. Policies for data sharing should be responsive to public views, but there is little evidence of the systematic study of these from low-income countries. This qualitative study explored views on fair data-sharing processes among 60 stakeholders in Kenya with varying research experience, using a deliberative approach. Stakeholders’ attitudes were informed by perceptions of benefit and concerns for research data sharing, including risks of stigmatization, loss of privacy, and undermining scientific careers and validity, reported in detail elsewhere. In this article, we discuss institutional trust-building processes seen as central to perceptions of fairness in sharing research data in this setting, including forms of community involvement, individual prior awareness and agreement to data sharing, independence and accountability of governance mechanisms, and operating under a national framework. PMID:26297748

  9. Professional Use of Social Media by Pharmacists: A Qualitative Study.

    PubMed

    Benetoli, Arcelio; Chen, Timothy Frank; Schaefer, Marion; Chaar, Betty B; Aslani, Parisa

    2016-09-23

    Social media is frequently used by consumers and health care professionals; however, our knowledge about its use in a professional capacity by pharmacists is limited. Our aim was to investigate the professional use of social media by pharmacists. In-depth semistructured interviews were conducted with practicing pharmacists (N=31) from nine countries. Interviews were recorded, transcribed verbatim, and thematically analyzed. Wikipedia, YouTube, and Facebook were the main social media platforms used. Professional use of social media included networking with peers, discussion of health and professional topics, accessing and sharing health and professional information, job searching, and professional promotion. Wikipedia was the participants' first choice when seeking information about unfamiliar topics, or topics that were difficult to search for. Very few pharmacy-related contributions to Wikipedia were reported. YouTube, a video-sharing platform, was used for self-education. University lectures, "how-to" footage, and professionally made videos were commonly watched. No professional contribution was made to YouTube. Facebook, a general social networking site, was used for professional networking, promotion of achievements, and job advertisements. It also afforded engagement in professional discussions and information sharing among peers. Participants used social media in a professional capacity, specifically for accessing and sharing health and professional information among peers. Pharmacists, as medicines experts, should take a leading role in contributing to health information dissemination in these user-friendly virtual environments, to reach not only other health care professionals but also health consumers.

  10. Professional Use of Social Media by Pharmacists: A Qualitative Study

    PubMed Central

    Benetoli, Arcelio; Chen, Timothy Frank; Schaefer, Marion; Chaar, Betty B

    2016-01-01

    Background Social media is frequently used by consumers and health care professionals; however, our knowledge about its use in a professional capacity by pharmacists is limited. Objective Our aim was to investigate the professional use of social media by pharmacists. Methods In-depth semistructured interviews were conducted with practicing pharmacists (N=31) from nine countries. Interviews were recorded, transcribed verbatim, and thematically analyzed. Results Wikipedia, YouTube, and Facebook were the main social media platforms used. Professional use of social media included networking with peers, discussion of health and professional topics, accessing and sharing health and professional information, job searching, and professional promotion. Wikipedia was the participants’ first choice when seeking information about unfamiliar topics, or topics that were difficult to search for. Very few pharmacy-related contributions to Wikipedia were reported. YouTube, a video-sharing platform, was used for self-education. University lectures, “how-to” footage, and professionally made videos were commonly watched. No professional contribution was made to YouTube. Facebook, a general social networking site, was used for professional networking, promotion of achievements, and job advertisements. It also afforded engagement in professional discussions and information sharing among peers. Conclusions Participants used social media in a professional capacity, specifically for accessing and sharing health and professional information among peers. Pharmacists, as medicines experts, should take a leading role in contributing to health information dissemination in these user-friendly virtual environments, to reach not only other health care professionals but also health consumers. PMID:27663570

  11. Radiologic image communication and archive service: a secure, scalable, shared approach

    NASA Astrophysics Data System (ADS)

    Fellingham, Linda L.; Kohli, Jagdish C.

    1995-11-01

    The Radiologic Image Communication and Archive (RICA) service is designed to provide a shared archive for medical images to the widest possible audience of customers. Images are acquired from a number of different modalities, each available from many different vendors. Images are acquired digitally from those modalities which support direct digital output and by digitizing films for projection x-ray exams. The RICA Central Archive receives standard DICOM 3.0 messages and data streams from the medical imaging devices at customer institutions over the public telecommunication network. RICA represents a completely scalable resource. The user pays only for what he is using today with the full assurance that as the volume of image data that he wishes to send to the archive increases, the capacity will be there to accept it. To provide this seamless scalability imposes several requirements on the RICA architecture: (1) RICA must support the full array of transport services. (2) The Archive Interface must scale cost-effectively to support local networks that range from the very small (one x-ray digitizer in a medical clinic) to the very large and complex (a large hospital with several CTs, MRs, Nuclear medicine devices, ultrasound machines, CRs, and x-ray digitizers). (3) The Archive Server must scale cost-effectively to support rapidly increasing demands for service providing storage for and access to millions of patients and hundreds of millions of images. The architecture must support the incorporation of improved technology as it becomes available to maintain performance and remain cost-effective as demand rises.

  12. Historical trends and projections of land use for the South-Central United States.

    Treesearch

    SoEun Ahn; Andrew J. Plantinga; Ralph J. Alig

    2000-01-01

    This report presents historical trends and future projections of forest, agricultural, and urban and other land uses for the South-Central United States. A land use share model is used to investigate the relation between the areas of land in alternative uses and economic and demographic factors influencing land use decisions. Two different versions of the empirical...

  13. College Curriculum-Sharing Via CTS.

    ERIC Educational Resources Information Center

    Hudson, Heather E.; And Others

    Domestic communication satellites and video compression techniques will increase communication channel capacity and reduce cost of video transmission. The National Aeronautics and Space Administration Ames Research Center, Stanford University, and Carleton University are participants in an experiment to develop, demonstrate, and evaluate the…

  14. Elements for harnessing participatory action research to strengthen health managers' capacity: a critical interpretative synthesis.

    PubMed

    Tetui, Moses; Zulu, Joseph Mumba; Hurtig, Anna-Karin; Ekirapa-Kiracho, Elizabeth; Kiwanuka, Suzanne N; Coe, Anna-Britt

    2018-04-19

    Health managers play a key role in ensuring that health services are responsive to the needs of the population. Participatory action research (PAR) is one of the approaches that have been used to strengthen managers' capacity. However, collated knowledge on elements for harnessing PAR to strengthen managers' capacity is missing. This paper bridges this gap by reviewing existing literature on the subject matter. A critical interpretive synthesis method was used to interrogate eight selected articles. These articles reported the use of PAR to strengthen health managers' capacity. The critical interpretive synthesis method's approach to analysis guided the synthesis. Here, the authors interpretively made connections and linkages between different elements identified in the literature. Finally, the Atun et al. (Heal Pol Plann, 25:104-111, 2010) framework on integration was used to model the elements synthesised in the literature into five main domains. Five elements with intricate bi-directional interactions were identified in the literature reviewed. These included a shared purpose, skilled facilitation and psychological safety, activity integration into organisational procedures, organisational support, and external supportive monitoring. A shared purpose of the managers' capacity strengthening initiative created commitment and motivation to learn. This purpose was built upon a set of facilitation skills that included promoting participation, self-efficacy and reflection, thereby creating a safe psychological space within which the managers interacted and learnt from each other and their actions. Additionally, an integrated intervention strengthened local capacity and harnessed organisational support for learning. Finally, supportive monitoring from external partners, such as researchers, ensured quality, building of local capacity and professional safety networks essential for continued learning. The five elements identified in this synthesis provide a basis upon which the use of PAR can be harnessed, not only to strengthen health managers' capacity, but also to foster other health systems strengthening initiatives involving implementation research. In addition, the findings demonstrated the intricate and complex relations between the elements, which further affirms the need for a systems thinking approach to tackling health systems challenges.

  15. Data Democratization - Promoting Real-Time Data Sharing and Use Worldwide

    NASA Astrophysics Data System (ADS)

    Yoksas, T. C.; Almeida, W. G.; Leon, V. C.

    2007-05-01

    The Unidata Program Center (Unidata) of the University Corporation of Atmospheric Research (UCAR) is actively involved in international collaborations whose goals are the free-and-open sharing of hydro-meteorological data; the distribution of analysis and visualization tools for those data; the establishment of server technologies that provide easy-to-use, programmatic remote-access to a wide variety of datasets, and in the building of a community where data, tools, and best practices in education and research are shared. The tools and services provided by Unidata are available to the research and education community free-of-charge. Data sharing capabilities are being provided by Unidata's Internet Data Distribution (IDD) system, a community-based effort that has been the primary source of real-time meteorological data in the US university community for over a decade. A collaboration among Unidata, Brazil's Centro de Previso de Tempo e Estudos Climaticos (CPTEC), the Universidad Federal do Rio de Janeiro (UFRJ), and the Universidade de Sao Paulo (USP) has resulted in the creation of a Brazilian peer of the North American IDD, the IDD-Brasil. Collaboration between Unidata and the Universidad de Costa Rica (UCR) seeks to extend IDD data sharing throughout Central America and the Caribbean in an IDD-Caribe. Efforts aimed at creating a data sharing network for researchers on the Antarctic continent have resulted in the establishment of the Antarctic-IDD. Most recently, explorations of data sharing between UCAR and select countries in Africa have begun. Data analysis and visualization capabilities are available through Unidata in a suite of freely-available applications: the National Centers for Environmental Prediction (NCEP) GEneral Meteorology PAcKage (GEMPAK); the Unidata Integrated Data Viewer (IDV); and University of Wisconsin, Space Science and Engineering Center (SSEC) Man-computer Interactive Data Access System (McIDAS). Remote data access capabilities are provided by Unidata's Thematic Realtime Environmental Data Services (THREDDS) servers (which incorporate Open-source Project for a Network Data Access (OPeNDAP) data services), and the Abstract Data Distribution Environment (ADDE) of McIDAS. It is envisioned that the data sharing capabilities available in the IDD, IDD-Brasil, IDD-Caribe, and Antarctic-IDD, remote data access capabilities available in THREDDS and ADDE, and analysis capabilities available in GEMPAK, the IDV, and McIDAS will help foster new collaborations among prominent universities, national meteorological agencies, and WMO Regional Meteorological Training Centers throughout North, Central, and South America, in the Antarctic research community, and eventually in Africa. This paper is intended to inform AGU 2007 Joint Assembly attendees, especially those in Mexico and Central America, of the availability of real-time data and tools to analyze/visualize those data, and to promote the free-and-open sharing of data, especially of locally-held datasets of general interest.

  16. Evidence for shared cognitive processing of pitch in music and language.

    PubMed

    Perrachione, Tyler K; Fedorenko, Evelina G; Vinke, Louis; Gibson, Edward; Dilley, Laura C

    2013-01-01

    Language and music epitomize the complex representational and computational capacities of the human mind. Strikingly similar in their structural and expressive features, a longstanding question is whether the perceptual and cognitive mechanisms underlying these abilities are shared or distinct--either from each other or from other mental processes. One prominent feature shared between language and music is signal encoding using pitch, conveying pragmatics and semantics in language and melody in music. We investigated how pitch processing is shared between language and music by measuring consistency in individual differences in pitch perception across language, music, and three control conditions intended to assess basic sensory and domain-general cognitive processes. Individuals' pitch perception abilities in language and music were most strongly related, even after accounting for performance in all control conditions. These results provide behavioral evidence, based on patterns of individual differences, that is consistent with the hypothesis that cognitive mechanisms for pitch processing may be shared between language and music.

  17. Food Sharing across Borders : First Observation of Intercommunity Meat Sharing by Bonobos at LuiKotale, DRC.

    PubMed

    Fruth, Barbara; Hohmann, Gottfried

    2018-06-01

    Evolutionary models consider hunting and food sharing to be milestones that paved the way from primate to human societies. Because fossil evidence is scarce, hominoid primates serve as referential models to assess our common ancestors' capacity in terms of communal use of resources, food sharing, and other forms of cooperation. Whereas chimpanzees form male-male bonds exhibiting resource-defense polygyny with intolerance and aggression toward nonresidents, bonobos form male-female and female-female bonds resulting in relaxed relations with neighboring groups. Here we report the first known case of meat sharing between members of two bonobo communities, revealing a new dimension of social tolerance in this species. This observation testifies to the behavioral plasticity that exists in the two Pan species and contributes to scenarios concerning the traits of the last common ancestor of Pan and Homo. It also contributes to the discussion of physiological triggers of in-group/out-group behavior and allows reconsideration of the emergence of social norms in prehuman societies.

  18. Sharing possibilities amongst CDMA Mobile Satellite Systems, and impacts of terminal characteristics on sharing

    NASA Astrophysics Data System (ADS)

    Bambace, Luís Antonio Waack; Ceballos, Décio Castilho

    CDMA Mobile Satellite Systems (CDMA MSS) are able to co-directional, co-frequency and co-coverage sharing, and they are strongly interdependent in case of such a sharing. It is also known that the success of any telecommunication project is the use of the correct media to each task. Operators have a clear sight of such a media adequacy in traditional systems, but not necessarily in the case of Mobile Satellite Systems. This creates a risk that a wrong market objective operator causes trouble to other systems. This paper deals with the sharing alternatives for up to four CDMA MSS operating in the same frequency band, and analysts both: satellite to user downlink and user to satellite uplink. The influence of several items in capacity is here treated. The scope includes: downlink power flux density: code availability; single system internal interference; inter-system interference; diversity schemes: average link impairments, margins; user cooperation; terminal specifications and the dependence of the insulation between RHCP and LHCP with fade.

  19. Job Sharing for Women Pharmacists in Academia

    PubMed Central

    Finks, Shannon W.

    2009-01-01

    The pharmacist shortage, increasing numbers of female pharmacy graduates, more pharmacy schools requiring faculty members, and a lower percentage of female faculty in academia are reasons to develop unique arrangements for female academic pharmacists who wish to work part-time. Job sharing is an example of a flexible alternative work arrangement that can be successful for academic pharmacists who wish to continue in a part-time capacity. Such partnerships have worked for other professionals but have not been widely adopted in pharmacy academia. Job sharing can benefit the employer through retention of experienced employees who collectively offer a wider range of skills than a single employee. Benefits to the employee include balanced work and family lives with the ability to maintain their knowledge and skills by remaining in the workforce. We discuss the additional benefits of job-sharing as well as our experience in a non-tenure track job-sharing position at the University of Tennessee College of Pharmacy. PMID:19960092

  20. Symmetric reconfigurable capacity assignment in a bidirectional DWDM access network.

    PubMed

    Ortega, Beatriz; Mora, José; Puerto, Gustavo; Capmany, José

    2007-12-10

    This paper presents a novel architecture for DWDM bidirectional access networks providing symmetric dynamic capacity allocation for both downlink and uplink signals. A foldback arrayed waveguide grating incorporating an optical switch enables the experimental demonstration of flexible assignment of multiservice capacity. Different analog and digital services, such as CATV, 10 GHz-tone, 155Mb/s PRBS and UMTS signals have been transmitted in order to successfully test the system performance under different scenarios of total capacity distribution from the Central Station to different Base Stations with two reconfigurable extra channels for each down and upstream direction.

  1. A Novel Capacity Analysis for Wireless Backhaul Mesh Networks

    NASA Astrophysics Data System (ADS)

    Chung, Tein-Yaw; Lee, Kuan-Chun; Lee, Hsiao-Chih

    This paper derived a closed-form expression for inter-flow capacity of a backhaul wireless mesh network (WMN) with centralized scheduling by employing a ring-based approach. Through the definition of an interference area, we are able to accurately describe a bottleneck collision area for a WMN and calculate the upper bound of inter-flow capacity. The closed-form expression shows that the upper bound is a function of the ratio between transmission range and network radius. Simulations and numerical analysis show that our analytic solution can better estimate the inter-flow capacity of WMNs than that of previous approach.

  2. Improved Efficient Routing Strategy on Scale-Free Networks

    NASA Astrophysics Data System (ADS)

    Jiang, Zhong-Yuan; Liang, Man-Gui

    Since the betweenness of nodes in complex networks can theoretically represent the traffic load of nodes under the currently used routing strategy, we propose an improved efficient (IE) routing strategy to enhance to the network traffic capacity based on the betweenness centrality. Any node with the highest betweenness is susceptible to traffic congestion. An efficient way to improve the network traffic capacity is to redistribute the heavy traffic load from these central nodes to non-central nodes, so in this paper, we firstly give a path cost function by considering the sum of node betweenness with a tunable parameter β along the actual path. Then, by minimizing the path cost, our IE routing strategy achieved obvious improvement on the network transport efficiency. Simulations on scale-free Barabási-Albert (BA) networks confirmed the effectiveness of our strategy, when compared with the efficient routing (ER) and the shortest path (SP) routing.

  3. 76 FR 20713 - Bureau of International Labor Affairs; Office of Trade and Labor Affairs; Request for Comments on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ...This notice is a request for comments from the public to assist the Secretary of Labor and the United States Trade Representative in preparing a report on labor capacity-building efforts under Chapter 16 (``the Labor Chapter'') and Annex 16.5 of the Dominican Republic--Central America--United States Free Trade Agreement (``the CAFTA-DR''), as well as efforts made by the CAFTA-DR countries to implement the recommendations contained in the report entitled ``The Labor Dimension in Central America and the Dominican Republic--Building on Progress: Strengthening Compliance and Enhancing Capacity'' (``the White Paper''). This report is required under the Dominican Republic-- Central America--United States Free Trade Agreement Implementation Act (``the CAFTA-DR Implementation Act''). The reporting function and the responsibility for soliciting public comments required under this Act were assigned to the Secretary of Labor, in consultation with the United States Trade Representative.

  4. Twiddlenet: Metadata Tagging and Data Dissemination in Mobile Device Networks

    DTIC Science & Technology

    2007-09-01

    hosting a distributed data dissemination application. Stated simply, there are a multitude of handheld devices on the market that can communicate in...content ( UGC ) across a network of distributed devices. This sharing is accomplished through the use of descriptive metadata tags that are assigned to a...file once it has been shared. These metadata files are uploaded to a centralized portal and arranged for efficient UGC location and searching

  5. Industry Study, Electronics Industry, Spring 2009

    DTIC Science & Technology

    2009-01-01

    Toshiba, Samsung , and NEC.7 The microprocessor is a central processing unit containing hundreds of millions of transistors and logic to perform...business with an 11.7% market share followed closely by Samsung with a 10.3% market share.40 Intel is the leader in the production of microprocessors...while Samsung is the leading memory chip producer. Other US chip manufacturers include Texas Instruments (TI), Advanced Micro Devices (AMD), Micron

  6. Independent Contributions of the Central Executive, Intelligence, and In-Class Attentive Behavior to Developmental Change in the Strategies Used to Solve Addition Problems

    PubMed Central

    Geary, David C.; Hoard, Mary K.; Nugent, Lara

    2012-01-01

    Children’s (n = 275) use of retrieval, decomposition (e.g., 7 = 4+3, and thus 6+7=6+4+3), and counting to solve additional problems was longitudinally assessed from first to fourth grade, and intelligence, working memory, and in-class attentive behavior was assessed in one or several grades. The goal was to assess the relation between capacity of the central executive component of working memory, controlling for intelligence and in-class attentive behavior, and grade-related changes in children’s use of these strategies. The predictor on intercept effects from multilevel models revealed that children with higher central executive capacity correctly retrieved more facts and used the most sophisticated counting procedure more frequently and accurately than did their lower capacity peers at the beginning of first grade, but the predictor on slope effects indicated that this advantage disappeared (retrieval) or declined in importance (counting) from first to fourth grade. The predictor on slope effects also revealed that from first through fourth grade, children with higher capacity adopted the decomposition strategy more quickly than did other children. The results remained robust with controls for children’s sex, race, school site, speed of encoding Arabic numerals and articulating number words, and mathematics achievement in kindergarten. The results also revealed that intelligence and in-class attentive behavior independently contributed to children’s strategy development. PMID:22698947

  7. Independent contributions of the central executive, intelligence, and in-class attentive behavior to developmental change in the strategies used to solve addition problems.

    PubMed

    Geary, David C; Hoard, Mary K; Nugent, Lara

    2012-09-01

    Children's (N=275) use of retrieval, decomposition (e.g., 7=4+3 and thus 6+7=6+4+3), and counting to solve additional problems was longitudinally assessed from first grade to fourth grade, and intelligence, working memory, and in-class attentive behavior was assessed in one or several grades. The goal was to assess the relation between capacity of the central executive component of working memory, controlling for intelligence and in-class attentive behavior, and grade-related changes in children's use of these strategies. The predictor on intercept effects from multilevel models revealed that children with higher central executive capacity correctly retrieved more facts and used the most sophisticated counting procedure more frequently and accurately than their lower capacity peers at the beginning of first grade, but the predictor on slope effects indicated that this advantage disappeared (retrieval) or declined in importance (counting) from first grade to fourth grade. The predictor on slope effects also revealed that from first grade to fourth grade, children with higher capacity adopted the decomposition strategy more quickly than other children. The results remained robust with controls for children's sex, race, school site, speed of encoding Arabic numerals and articulating number words, and mathematics achievement in kindergarten. The results also revealed that intelligence and in-class attentive behavior independently contributed to children's strategy development. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Shared decision-making at the end of life: A focus group study exploring the perceptions and experiences of multi-disciplinary healthcare professionals working in the home setting.

    PubMed

    Brogan, Paula; Hasson, Felicity; McIlfatrick, Sonja

    2018-01-01

    Globally recommended in healthcare policy, Shared Decision-Making is also central to international policy promoting community palliative care. Yet realities of implementation by multi-disciplinary healthcare professionals who provide end-of-life care in the home are unclear. To explore multi-disciplinary healthcare professionals' perceptions and experiences of Shared Decision-Making at end of life in the home. Qualitative design using focus groups, transcribed verbatim and analysed thematically. A total of 43 participants, from multi-disciplinary community-based services in one region of the United Kingdom, were recruited. While the rhetoric of Shared Decision-Making was recognised, its implementation was impacted by several interconnecting factors, including (1) conceptual confusion regarding Shared Decision-Making, (2) uncertainty in the process and (3) organisational factors which impeded Shared Decision-Making. Multiple interacting factors influence implementation of Shared Decision-Making by professionals working in complex community settings at the end of life. Moving from rhetoric to reality requires future work exploring the realities of Shared Decision-Making practice at individual, process and systems levels.

  9. Network Centrality of Metro Systems

    PubMed Central

    Derrible, Sybil

    2012-01-01

    Whilst being hailed as the remedy to the world’s ills, cities will need to adapt in the 21st century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the evolution of centrality with network size and examine several individual systems in more detail. Betweenness was notably found to consistently become more evenly distributed with size (i.e. no “winner takes all”) unlike other complex network properties. Two distinct regimes were also observed that are representative of their structure. Moreover, the share of betweenness was found to decrease in a power law with size (with exponent 1 for the average node), but the share of most central nodes decreases much slower than least central nodes (0.87 vs. 2.48). Finally the betweenness of individual stations in several systems were examined, which can be useful to locate stations where passengers can be redistributed to relieve pressure from overcrowded stations. Overall, this study offers significant insights that can help planners in their task to design the systems of tomorrow, and similar undertakings can easily be imagined to other urban infrastructure systems (e.g., electricity grid, water/wastewater system, etc.) to develop more sustainable cities. PMID:22792373

  10. Distinct neural markers of TVA-based visual processing speed and short-term storage capacity parameters.

    PubMed

    Wiegand, Iris; Töllner, Thomas; Habekost, Thomas; Dyrholm, Mads; Müller, Hermann J; Finke, Kathrin

    2014-08-01

    An individual's visual attentional capacity is characterized by 2 central processing resources, visual perceptual processing speed and visual short-term memory (vSTM) storage capacity. Based on Bundesen's theory of visual attention (TVA), independent estimates of these parameters can be obtained from mathematical modeling of performance in a whole report task. The framework's neural interpretation (NTVA) further suggests distinct brain mechanisms underlying these 2 functions. Using an interindividual difference approach, the present study was designed to establish the respective ERP correlates of both parameters. Participants with higher compared to participants with lower processing speed were found to show significantly reduced visual N1 responses, indicative of higher efficiency in early visual processing. By contrast, for participants with higher relative to lower vSTM storage capacity, contralateral delay activity over visual areas was enhanced while overall nonlateralized delay activity was reduced, indicating that holding (the maximum number of) items in vSTM relies on topographically specific sustained activation within the visual system. Taken together, our findings show that the 2 main aspects of visual attentional capacity are reflected in separable neurophysiological markers, validating a central assumption of NTVA. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  11. Decision-making capacity and competency in the elderly: a clinical and neuropsychological perspective.

    PubMed

    Moberg, Paul J; Rick, Jacqueline H

    2008-01-01

    With our ageing population, the number of older adults with cognitive impairment has also increased. There is both an acute and growing need for evidence-based assessments to identify their decision making capacity and competence. In the present article we (1) present definitions of decision-making capacity and competence, (2) review cognitive functions that are central to decision-making capacity as well as the methods and procedures commonly used to assess these domains, and (3) address the communication of assessment findings to patients and their loved ones. The importance of assessing decision-making capacity in the context of specific functions and of respecting the values and interests of older adults are emphasized.

  12. A Next-Generation Parallel File System Environment for the OLCF

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dillow, David A; Fuller, Douglas; Gunasekaran, Raghul

    2012-01-01

    When deployed in 2008/2009 the Spider system at the Oak Ridge National Laboratory s Leadership Computing Facility (OLCF) was the world s largest scale Lustre parallel file system. Envisioned as a shared parallel file system capable of delivering both the bandwidth and capacity requirements of the OLCF s diverse computational environment, Spider has since become a blueprint for shared Lustre environments deployed worldwide. Designed to support the parallel I/O requirements of the Jaguar XT5 system and other smallerscale platforms at the OLCF, the upgrade to the Titan XK6 heterogeneous system will begin to push the limits of Spider s originalmore » design by mid 2013. With a doubling in total system memory and a 10x increase in FLOPS, Titan will require both higher bandwidth and larger total capacity. Our goal is to provide a 4x increase in total I/O bandwidth from over 240GB=sec today to 1TB=sec and a doubling in total capacity. While aggregate bandwidth and total capacity remain important capabilities, an equally important goal in our efforts is dramatically increasing metadata performance, currently the Achilles heel of parallel file systems at leadership. We present in this paper an analysis of our current I/O workloads, our operational experiences with the Spider parallel file systems, the high-level design of our Spider upgrade, and our efforts in developing benchmarks that synthesize our performance requirements based on our workload characterization studies.« less

  13. [How many kids are there with excess weight? What information should be published?

    PubMed

    Pérez-Ríos, Mónica; Santiago-Pérez, María I; Malvar Pintos, Alberto; Suanzes Hernández, Jorge; Hervada Vidal, Xurxo

    2018-06-11

    In epidemiological studies, there is no consensus on which references should be used to characterize the weight status of schoolchildren after estimating their body mass index. The aim of this study is to evaluate the influence that different criteria have on the characterization of the weight status of Galician schoolchildren from 6 to 15 years old and to identify the criterion that best characterizes central obesity. Cross-sectional study on a sample of 7.438 schoolchildren representative by sex and age of the Galician population of 6 to 15 year olds. The prevalence of central obesity and underweight, normal weight, overweight and obesity was estimated using the reference standards of the World Health Organization (WHO), Cole, Orbegozo-2011 and the Enkid study. In order to identify the criterion that best characterizes central obesity, the positive predictive values of obesity and the negative ones of overweight and obesity were calculated. The characterization of schoolchildren according to their weight status was different depending on the reference used with estimates that vary by 20.4 percentage points being prevalence of excess weight using WHO references 41.5% while with Enkid it is 21.1%. The reference with the best predictive capacity of central obesity was those proposed by Cole. The variability observed in the characterization of the weight status of schoolchildren asso- ciated with the use of different reference criteria is very important. If central obesity is a good indicator of excess of weight, the reference proposed by Cole would be the one with the best capacity to characterize the child and youth population, related to the best predictive capacity.

  14. In Abundance: Networked Participatory Practices as Scholarship

    ERIC Educational Resources Information Center

    Stewart, Bonnie E.

    2015-01-01

    In an era of knowledge abundance, scholars have the capacity to distribute and share ideas and artifacts via digital networks, yet networked scholarship often remains unrecognized within institutional spheres of influence. Using ethnographic methods including participant observation, interviews, and document analysis, this study investigates…

  15. 77 FR 40413 - Third-Party Provision of Ancillary Services; Accounting and Financial Reporting for New Electric...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... share on that basis. \\52\\ For example, the Commission has allowed wind generating facilities that lack five years of operational data to use a five- year average regional wind capacity factor based on data...

  16. Understanding District-Charter Collaboration Grants. Final Report

    ERIC Educational Resources Information Center

    Tuttle, Christina; McCullough, Moira; Richman, Scott; Booker, Kevin; Burnett, Alyson; Keating, Betsy; Cavanaugh, Michael

    2016-01-01

    In November 2012, the Bill & Melinda Gates Foundation invested in seven innovative district-charter partnerships with "the potential capacity and commitment to accelerate student college ready rates through deep collaboration and sharing of best practices" (District-Charter Collaboration Grant Request for Proposal [RFP]). These…

  17. Centralized automated cataloging of health science materials in the MLC/SUNY/OCLC shared cataloging service.

    PubMed Central

    Raper, J E

    1977-01-01

    Since February 1976, The Medical Library Center of New York, with the assistance of the SUNY/OCLC Network, has offered, on a subscription basis, a centralized automated cataloging service to health science libraries in the greater metropolitan New York area. By using workforms and prints of OCLC record (amended by the subscribing participants), technical services personnel at the center have fed cataloging data, via a CRT terminal, into the OCLC system, which provides (1) catalog cards, received in computer filing order; (2) book card, spine, and pocket labels; (3) accessions lists; and (4) data for eventual production of book catalogs and union catalogs. The experience of the center in the development, implementation, operation, and budgeting of its shared cataloging service is discussed. PMID:843650

  18. Centralized automated cataloging of health science materials in the MLC/SUNY/OCLC shared cataloging service.

    PubMed

    Raper, J E

    1977-04-01

    Since February 1976, The Medical Library Center of New York, with the assistance of the SUNY/OCLC Network, has offered, on a subscription basis, a centralized automated cataloging service to health science libraries in the greater metropolitan New York area. By using workforms and prints of OCLC record (amended by the subscribing participants), technical services personnel at the center have fed cataloging data, via a CRT terminal, into the OCLC system, which provides (1) catalog cards, received in computer filing order; (2) book card, spine, and pocket labels; (3) accessions lists; and (4) data for eventual production of book catalogs and union catalogs. The experience of the center in the development, implementation, operation, and budgeting of its shared cataloging service is discussed.

  19. Decision on risk-averse dual-channel supply chain under demand disruption

    NASA Astrophysics Data System (ADS)

    Yan, Bo; Jin, Zijie; Liu, Yanping; Yang, Jianbo

    2018-02-01

    We studied dual-channel supply chains using centralized and decentralized decision-making models. We also conducted a comparative analysis of the decisions before and after demand disruption. The study shows that the amount of change in decision-making is a linear function of the amount of demand disruption, and it is independent of the risk-averse coefficient. The optimal sales volume decision of the disturbing supply chain is related to market share and demand disruption in the decentralized decision-making model. The optimal decision is only influenced by demand disruption in the centralized decision-making model. The stability of the sales volume of the two models is related to market share and demand disruption. The optimal system production of the two models shows robustness, but their stable internals are different.

  20. Managing diminished irrigation capacity with preseason irrigation and plant density for corn production

    USDA-ARS?s Scientific Manuscript database

    Many of the irrigation systems today in the U.S. Central Great Plains no longer have the capacity to match peak irrigation needs during the summer and must rely on soil water reserves to buffer the crop from water stress. Considerable research was conducted on preseason irrigation in the U.S. Great ...

  1. After the Fall: The Use of Surplus Capacity in an Academic Library Automation System.

    ERIC Educational Resources Information Center

    Wright, A. J.

    The possible uses of excess central processing unit capacity in an integrated academic library automation system discussed in this draft proposal include (1) in-house services such as word processing, electronic mail, management decision support using PERT/CPM techniques, and control of physical plant operation; (2) public services such as the…

  2. Individual Differences in Working Memory Capacity and Dual-Process Theories of the Mind

    ERIC Educational Resources Information Center

    Barrett, Lisa Feldman; Tugade, Michele M.; Engle, Randall W.

    2004-01-01

    Dual-process theories of the mind are ubiquitous in psychology. A central principle of these theories is that behavior is determined by the interplay of automatic and controlled processing. In this article, the authors examine individual differences in the capacity to control attention as a major contributor to differences in working memory…

  3. Value of Coaching in Building Leadership Capacity of Principals in Urban Schools: A Case Study

    ERIC Educational Resources Information Center

    Farver, Anita

    2014-01-01

    The purpose of this qualitative case study was to understand how coaching support structures enabled and sustained leadership practices of urban principals. The study investigated how the intervention of coaching for academic leaders can serve as evidence based professional development for building leadership capacity. The central focus was on…

  4. Cognitive Load Theory, Educational Research, and Instructional Design: Some Food for Thought

    ERIC Educational Resources Information Center

    de Jong, Ton

    2010-01-01

    Cognitive load is a theoretical notion with an increasingly central role in the educational research literature. The basic idea of cognitive load theory is that cognitive capacity in working memory is limited, so that if a learning task requires too much capacity, learning will be hampered. The recommended remedy is to design instructional systems…

  5. Building Teachers' Data-Use Capacity: Insights from Strong and Developing Coaches

    ERIC Educational Resources Information Center

    Huguet, Alice; Marsh, Julie A.; Farrell, Caitlin C.

    2014-01-01

    Coaching has become a central strategy in district and school efforts to build teacher capacity to interpret and respond to student learning data. Despite their popularity, there is limited research on the implementation of these initiatives. This article begins to addresses this gap by examining the elements of a coach's practice that appear…

  6. Calculating the ecosystem service of water storage in isolated wetlands using LiDAR in north central Florida, USA (presentation)

    EPA Science Inventory

    This study used remotely-sensed Light Detection and Ranging (LiDAR) data to estimate potential water storage capacity of isolated wetlands in north central Florida. The data were used to calculate the water storage potential of >8500 polygons identified as isolated wetlands. We f...

  7. Impact of Working Memory Training Targeting the Central Executive on Kindergarteners' Numerical Skills

    ERIC Educational Resources Information Center

    Honoré, Nastasya; Noël, Marie-Pascale

    2017-01-01

    Working memory capacities are associated with mathematical development. Many studies have tried to improve working memory abilities through training. Furthermore, the central executive has been shown to be the component of working memory, which is the most strongly related to numerical and arithmetical skills. Therefore, we developed a training…

  8. Calculating the ecosystem service of water storage in isolated wetlands using LIDAR in north central Florida, USA

    EPA Science Inventory

    This study used remotely-sensed Light Detection and Ranging (LiDAR) data to estimate potential water storage capacity of isolated wetlands in north central Florida. The data were used to calculate the water storage potential of >8500 polygons identified as isolated wetlands. We ...

  9. Growth-simulation model for lodgepole pine in central Oregon.

    Treesearch

    Walter G. Dahms

    1983-01-01

    A growth-simulation model for central Oregon lodgepole pine (Pinus contorta Dougl.) has been constructed by combining data from temporary and permanent sample plots. The model is similar to a conventional yield table with the added capacity for dealing with the stand-density variable. The simulator runs on a desk-top computer.

  10. Too Little and Too Much Trust: Performance Measurement in Australian Higher Education

    ERIC Educational Resources Information Center

    Woelert, Peter; Yates, Lyn

    2015-01-01

    A striking feature of contemporary Australian higher education governance is the strong emphasis on centralized, template style, metric-based, and consequential forms of performance measurement. Such emphasis is indicative of a low degree of political trust among the central authorities in Australia in the intrinsic capacity of universities and…

  11. A Computer Program for Training Eccentric Reading in Persons with Central Scotoma

    ERIC Educational Resources Information Center

    Kasten, Erich; Haschke, Peggy; Meinhold, Ulrike; Oertel-Verweyen, Petra

    2010-01-01

    This article explores the effectiveness of a computer program--Xcentric viewing--for training eccentric reading in persons with central scotoma. The authors conducted a small study to investigate whether this program increases the reading capacities of individuals with age-related macular degeneration (AMD). Instead of a control group, they…

  12. Multi-Model Assessment of Global Hydropower and Cooling Water Discharge Potential Under Climate Change

    NASA Technical Reports Server (NTRS)

    van Vliet, M. T. H.; van Beek, L. P. H.; Eisener, S.; Wada, Y.; Bierkens, M. F. P.

    2016-01-01

    Worldwide, 98% of total electricity is currently produced by thermoelectric power and hydropower. Climate change is expected to directly impact electricity supply, in terms of both water availability for hydropower generation and cooling water usage for thermoelectric power. Improved understanding of how climate change may impact the availability and temperature of water resources is therefore of major importance. Here we use a multi-model ensemble to show the potential impacts of climate change on global hydropower and cooling water discharge potential. For the first time, combined projections of streamflow and water temperature were produced with three global hydrological models (GHMs) to account for uncertainties in the structure and parametrization of these GHMs in both water availability and water temperature. The GHMs were forced with bias-corrected output of five general circulation models (GCMs) for both the lowest and highest representative concentration pathways (RCP2.6 and RCP8.5). The ensemble projections of streamflow and water temperature were then used to quantify impacts on gross hydropower potential and cooling water discharge capacity of rivers worldwide. We show that global gross hydropower potential is expected to increase between +2.4% (GCM-GHM ensemble mean for RCP 2.6) and +6.3% (RCP 8.5) for the 2080s compared to 1971-2000. The strongest increases in hydropower potential are expected for Central Africa, India, central Asia and the northern high-latitudes, with 18-33% of the world population living in these areas by the 2080s. Global mean cooling water discharge capacity is projected to decrease by 4.5-15% (2080s). The largest reductions are found for the United States, Europe, eastern Asia, and southern parts of South America, Africa and Australia, where strong water temperature increases are projected combined with reductions in mean annual streamflow. These regions are expected to affect 11-14% (for RCP2.6 and the shared socioeconomic pathway (SSP)1, SSP2, SSP4) and 41-51% (RCP8.5-SSP3, SSP5) of the world population by the 2080s.

  13. The manifold nature of interpersonal relations: the quest for a common mechanism.

    PubMed Central

    Gallese, Vittorio

    2003-01-01

    It has been proposed that the capacity to code the 'like me' analogy between self and others constitutes a basic prerequisite and a starting point for social cognition. It is by means of this self/other equivalence that meaningful social bonds can be established, that we can recognize others as similar to us, and that imitation can take place. In this article I discuss recent neurophysiological and brain imaging data on monkeys and humans, showing that the 'like me' analogy may rest upon a series of 'mirror-matching' mechanisms. A new conceptual tool able to capture the richness of the experiences we share with others is introduced: the shared manifold of intersubjectivity. I propose that all kinds of interpersonal relations (imitation, empathy and the attribution of intentions) depend, at a basic level, on the constitution of a shared manifold space. This shared space is functionally characterized by automatic, unconscious embodied simulation routines. PMID:12689377

  14. ADHD and working memory: the impact of central executive deficits and exceeding storage/rehearsal capacity on observed inattentive behavior.

    PubMed

    Kofler, Michael J; Rapport, Mark D; Bolden, Jennifer; Sarver, Dustin E; Raiker, Joseph S

    2010-02-01

    Inattentive behavior is considered a core and pervasive feature of ADHD; however, an alternative model challenges this premise and hypothesizes a functional relationship between working memory deficits and inattentive behavior. The current study investigated whether inattentive behavior in children with ADHD is functionally related to the domain-general central executive and/or subsidiary storage/rehearsal components of working memory. Objective observations of children's attentive behavior by independent observers were conducted while children with ADHD (n = 15) and typically developing children (n = 14) completed counterbalanced tasks that differentially manipulated central executive, phonological storage/rehearsal, and visuospatial storage/rehearsal demands. Results of latent variable and effect size confidence interval analyses revealed two conditions that completely accounted for the attentive behavior deficits in children with ADHD: (a) placing demands on central executive processing, the effect of which is evident under even low cognitive loads, and (b) exceeding storage/rehearsal capacity, which has similar effects on children with ADHD and typically developing children but occurs at lower cognitive loads for children with ADHD.

  15. Story of Stone Soup: A Recipe to Improve Health Disparities

    PubMed Central

    Chung, Bowen; Jones, Loretta; Terry, Chrystene; Jones, Andrea; Forge, Nell; Norris, Keith C.

    2013-01-01

    Just as scientific articles are used as a way of sharing knowledge in scientific communities, stories are used as a way of transferring knowledge within African American communities. This article uses the story and metaphor of Stone Soup to illustrate the Healthy African American Families' (HAAF) Community Partnered Participatory Research (CPPR) method of engaging diverse partners to address health issues, such as preterm birth, depression, diabetes, and kidney disease, and to create community-wide change through education, capacity building, resource sharing, and intervention development. PMID:20629241

  16. Ethical management guidelines for the shanghai disease-based biobank network.

    PubMed

    Zhu, Shu; Shen, Mingxian; Qiu, Xiangxing; Gan, Rongxing; Hu, Qingli

    2015-02-01

    The Ethical Management Guidelines for the Shanghai Disease-Based Biobank Network are intended to safeguard the interests of all the participants, to standardize the construction, management, and resource sharing of the Shanghai Disease-based Biobank Network, to promote the development of medical research, and to improve public health and well-being. The guidelines contain seven chapters: General Principles; Informed Consent; Use of Bio-samples from Persons without the Capacity to Consent; Privacy and Confidentiality; Applications of Use of Biological Samples and Data; Intellectual Property and Resource Sharing; and Conflict of Interest.

  17. Lack of agreement over the use and ownership of the internationally shared resources (such as air space, outer space and the oceans) leading to international conflict

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The lack of adequate institutional mechanisms to regulate, monitor and govern the use of commonly owned world resources appears to be politically destabilizing and subject to socioeconomic pressures of overpopulation, food shortages, cartelism, terrorism, and wealth distribution to developing countries. The capacity and propensity to wage war and its potential consequences are elaborated. It is shown that technology is one of the dominant factors affecting the exploration and management of commonly shared resources.

  18. Spatial heterogeneity in the carrying capacity of sika deer in Japan.

    PubMed

    Iijima, Hayato; Ueno, Mayumi

    2016-06-09

    Carrying capacity is 1 driver of wildlife population dynamics. Although in previous studies carrying capacity was considered to be a fixed entity, it may differ among locations due to environmental variation. The factors underlying variability in carrying capacity, however, have rarely been examined. Here, we investigated spatial heterogeneity in the carrying capacity of Japanese sika deer ( Cervus nippon ) from 2005 to 2014 in Yamanashi Prefecture, central Japan (mesh with grid cells of 5.5×4.6 km) by state-space modeling. Both carrying capacity and density dependence differed greatly among cells. Estimated carrying capacities ranged from 1.34 to 98.4 deer/km 2 . According to estimated population dynamics, grid cells with larger proportions of artificial grassland and deciduous forest were subject to lower density dependence and higher carrying capacity. We conclude that population dynamics of ungulates may vary spatially through spatial variation in carrying capacity and that the density level for controlling ungulate abundance should be based on the current density level relative to the carrying capacity for each area.

  19. The extent of interorganizational resource sharing among local health departments: the association with organizational characteristics and institutional factors.

    PubMed

    Vest, Joshua R; Shah, Gulzar H

    2012-11-01

    Resource sharing, arrangements between local health departments (LHDs) for joint programs or to share staff, is a growing occurrence. The post-9/11 influx of federal funding and new public health preparedness responsibilities dramatically increased the occurrence of these inter-LHD relationships, and several states have pursed more intrastate collaboration. This article describes the current state of resource sharing among LHDs and identifies the factors associated with resource sharing. Using the National Association of County & City Health Officials' 2010 Profile Survey, we determined the self-reported number of shared programmatic activities and the number of shared organizational functions for a sample of LHDs. Negative binomial regression models described the relationships between factors suggested by interorganizational theory and the counts of sharing activities. We examined the extent of resource sharing using 2 different count variables: (1) number of shared programmatic activities and (2) number of shared organizational functions. About one-half of all LHDs are engaged in resource sharing. The extent of sharing was lower for those serving larger populations, with city jurisdictions, or of larger size. Sharing was more extensive for state-governed LHDs, those covering multiple jurisdictions, states with centralized governance, and in instances of financial constraint. Many LHDs are engaged in a greater extent of resource sharing than others. Leaders of LHDs can work within the context of these factors to leverage resource sharing to meet their organizational needs.

  20. Correlations between human mobility and social interaction reveal general activity patterns.

    PubMed

    Mollgaard, Anders; Lehmann, Sune; Mathiesen, Joachim

    2017-01-01

    A day in the life of a person involves a broad range of activities which are common across many people. Going beyond diurnal cycles, a central question is: to what extent do individuals act according to patterns shared across an entire population? Here we investigate the interplay between different activity types, namely communication, motion, and physical proximity by analyzing data collected from smartphones distributed among 638 individuals. We explore two central questions: Which underlying principles govern the formation of the activity patterns? Are the patterns specific to each individual or shared across the entire population? We find that statistics of the entire population allows us to successfully predict 71% of the activity and 85% of the inactivity involved in communication, mobility, and physical proximity. Surprisingly, individual level statistics only result in marginally better predictions, indicating that a majority of activity patterns are shared across our sample population. Finally, we predict short-term activity patterns using a generalized linear model, which suggests that a simple linear description might be sufficient to explain a wide range of actions, whether they be of social or of physical character.

  1. Decision support for hospital bed management using adaptable individual length of stay estimations and shared resources

    PubMed Central

    2013-01-01

    Background Elective patient admission and assignment planning is an important task of the strategic and operational management of a hospital and early on became a central topic of clinical operations research. The management of hospital beds is an important subtask. Various approaches have been proposed, involving the computation of efficient assignments with regard to the patients’ condition, the necessity of the treatment, and the patients’ preferences. However, these approaches are mostly based on static, unadaptable estimates of the length of stay and, thus, do not take into account the uncertainty of the patient’s recovery. Furthermore, the effect of aggregated bed capacities have not been investigated in this context. Computer supported bed management, combining an adaptable length of stay estimation with the treatment of shared resources (aggregated bed capacities) has not yet been sufficiently investigated. The aim of our work is: 1) to define a cost function for patient admission taking into account adaptable length of stay estimations and aggregated resources, 2) to define a mathematical program formally modeling the assignment problem and an architecture for decision support, 3) to investigate four algorithmic methodologies addressing the assignment problem and one base-line approach, and 4) to evaluate these methodologies w.r.t. cost outcome, performance, and dismissal ratio. Methods The expected free ward capacity is calculated based on individual length of stay estimates, introducing Bernoulli distributed random variables for the ward occupation states and approximating the probability densities. The assignment problem is represented as a binary integer program. Four strategies for solving the problem are applied and compared: an exact approach, using the mixed integer programming solver SCIP; and three heuristic strategies, namely the longest expected processing time, the shortest expected processing time, and random choice. A baseline approach serves to compare these optimization strategies with a simple model of the status quo. All the approaches are evaluated by a realistic discrete event simulation: the outcomes are the ratio of successful assignments and dismissals, the computation time, and the model’s cost factors. Results A discrete event simulation of 226,000 cases shows a reduction of the dismissal rate compared to the baseline by more than 30 percentage points (from a mean dismissal ratio of 74.7% to 40.06% comparing the status quo with the optimization strategies). Each of the optimization strategies leads to an improved assignment. The exact approach has only a marginal advantage over the heuristic strategies in the model’s cost factors (≤3%). Moreover,this marginal advantage was only achieved at the price of a computational time fifty times that of the heuristic models (an average computing time of 141 s using the exact method, vs. 2.6 s for the heuristic strategy). Conclusions In terms of its performance and the quality of its solution, the heuristic strategy RAND is the preferred method for bed assignment in the case of shared resources. Future research is needed to investigate whether an equally marked improvement can be achieved in a large scale clinical application study, ideally one comprising all the departments involved in admission and assignment planning. PMID:23289448

  2. Decision support for hospital bed management using adaptable individual length of stay estimations and shared resources.

    PubMed

    Schmidt, Robert; Geisler, Sandra; Spreckelsen, Cord

    2013-01-07

    Elective patient admission and assignment planning is an important task of the strategic and operational management of a hospital and early on became a central topic of clinical operations research. The management of hospital beds is an important subtask. Various approaches have been proposed, involving the computation of efficient assignments with regard to the patients' condition, the necessity of the treatment, and the patients' preferences. However, these approaches are mostly based on static, unadaptable estimates of the length of stay and, thus, do not take into account the uncertainty of the patient's recovery. Furthermore, the effect of aggregated bed capacities have not been investigated in this context. Computer supported bed management, combining an adaptable length of stay estimation with the treatment of shared resources (aggregated bed capacities) has not yet been sufficiently investigated. The aim of our work is: 1) to define a cost function for patient admission taking into account adaptable length of stay estimations and aggregated resources, 2) to define a mathematical program formally modeling the assignment problem and an architecture for decision support, 3) to investigate four algorithmic methodologies addressing the assignment problem and one base-line approach, and 4) to evaluate these methodologies w.r.t. cost outcome, performance, and dismissal ratio. The expected free ward capacity is calculated based on individual length of stay estimates, introducing Bernoulli distributed random variables for the ward occupation states and approximating the probability densities. The assignment problem is represented as a binary integer program. Four strategies for solving the problem are applied and compared: an exact approach, using the mixed integer programming solver SCIP; and three heuristic strategies, namely the longest expected processing time, the shortest expected processing time, and random choice. A baseline approach serves to compare these optimization strategies with a simple model of the status quo. All the approaches are evaluated by a realistic discrete event simulation: the outcomes are the ratio of successful assignments and dismissals, the computation time, and the model's cost factors. A discrete event simulation of 226,000 cases shows a reduction of the dismissal rate compared to the baseline by more than 30 percentage points (from a mean dismissal ratio of 74.7% to 40.06% comparing the status quo with the optimization strategies). Each of the optimization strategies leads to an improved assignment. The exact approach has only a marginal advantage over the heuristic strategies in the model's cost factors (≤3%). Moreover,this marginal advantage was only achieved at the price of a computational time fifty times that of the heuristic models (an average computing time of 141 s using the exact method, vs. 2.6 s for the heuristic strategy). In terms of its performance and the quality of its solution, the heuristic strategy RAND is the preferred method for bed assignment in the case of shared resources. Future research is needed to investigate whether an equally marked improvement can be achieved in a large scale clinical application study, ideally one comprising all the departments involved in admission and assignment planning.

  3. Soils in our big back yard: characterizing the state, vulnerabilities, and opportunities for detecting changes in soil carbon storage

    NASA Astrophysics Data System (ADS)

    Harden, Jennifer W.; Loiesel, Julie; Ryals, Rebecca; Lawrence, Corey; Blankinship, Joseph; Phillips, Claire; Bond-Lamberty, Ben; Todd-Brown, Katherine; Vargas, Rodrigo; Hugelius, Gustaf; Nave, Luke; Malhotra, Avni; Silver, Whendee; Sanderman, Jon

    2017-04-01

    A number of diverse approaches and sciences can contribute to a robust understanding of the I. state, II. vulnerabilities, and III. opportunities for soil carbon in context of its potential contributions to the atmospheric C budget. Soil state refers to the current C stock of a given site, region, or ecosystem/landuse type. Soil vulnerabilities refers to the forms and bioreactivity of C stocks, which determine how soil C might respond to climate, disturbance, and landuse perturbations. Opportunities refer to the potential for soils in their current state to increase capacity for and rate of C storage under future conditions, thereby impacting atmospheric C budgets. In order to capture the state, vulnerability, and opportunities for soil C, a robust C accounting scheme must include at least three science needs: (1) a user-friendly and dynamic database with transparent, shared coding in which data layers of solid, liquid, and gaseous phases share relational metadata and allow for changes over time (2) a framework to characterize the capacity and reactivity of different soil types based on climate, historic, and landscape factors (3) a framework to characterize landuse practices and their impact on physical state, capacity/reactivity, and potential for C change. In order to transfer our science information to practicable implementations for land policies, societal and social needs must also include: (1) metrics for landowners and policy experts to recognize conditions of vulnerability or opportunity (2)communication schemes for accessing salient outcomes of the science. Importantly, there stands an opportunity for contributions of data, model code, and conceptual frameworks in which scientists, educators, and decision-makers can become citizens of a shared, scrutinized database that contributes to a dynamic, improved understanding of our soil system.

  4. Celebrating indigenous communities compassionate traditions.

    PubMed

    Prince, Holly

    2018-01-01

    Living in a compassionate community is not a new practice in First Nations communities; they have always recognized dying as a social experience. First Nations hold extensive traditional knowledge and have community-based practices to support the personal, familial, and community experiences surrounding end-of-life. However, western health systems were imposed and typically did not support these social and cultural practices at end of life. In fact, the different expectations of western medicine and the community related to end of life care has created stress and misunderstanding for both. One solution is for First Nations communities to develop palliative care programs so that people can receive care at home amongst their family, community and culture. Our research project "Improving End-of-Life Care in First Nations Communities" (EOLFN) was funded by the Canadian Institutes of Health Research [2010-2015] and was conducted in partnership with four First Nations communities in Canada (see www.eolfn.lakeheadu.ca). Results included a community capacity development approach to support Indigenous models of care at end-of-life. The workshop will describe the community capacity development process used to develop palliative care programs in First Nations communities. It will highlight the foundation to this approach, namely, grounding the program in community values and principles, rooted in individual, family, community and culture. Two First Nations communities will share stories about their experiences developing their own palliative care programs, which celebrated cultural capacity in their communities while enhancing medical palliative care services in a way that respected and integrated with their community cultural practices. This workshop shares the experiences of two First Nations communities who developed palliative care programs by building upon community culture, values and principles. The underlying model guiding development is shared.

  5. Financial and economic determinants of collective action: The case of wastewater management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brunner, Norbert, E-mail: norbert.brunner@cemds.org; Starkl, Markus, E-mail: markus.starkl@boku.ac.at

    Where public environmental funds support development of wastewater infrastructure, funding institutions ensure the economic use of funds, while the beneficiaries minimize their own costs. In rural areas, there is often a choice between decentralized or centralized (multi-village) systems: if the centralized system is most economic, then only this system is eligible for public funding. However, its implementation requires a voluntary cooperation of the concerned communities, who need to organize themselves to develop and run the infrastructure. The paper analyzes the social determinants of collaboration in a generic case study, using the following variables: method of (economic) assessment, modeled by themore » social discount rate, funding policy, modeled by the funding rate, and users' self-organization, modeled by cost sharing. In a borderline situation, where the centralized system turns out to be most economic, but this assessment is contingent on the assessment method, collective action may fail: the advantages of collective action from funding are too small to outweigh organizational deficiencies. Considering in this situation sanitation as a human right, authors recommend using innovative forms of organization and, if these fail, reassessing either the amount of funding or the eligibility for funding of more acceptable alternatives. - Highlights: Black-Right-Pointing-Pointer A generic case study models collective action and funding in wastewater management. Black-Right-Pointing-Pointer Determinants of success: economic assessment, funding policy and self-organization. Black-Right-Pointing-Pointer Success indicators: conflict rate, funds needed to make cost shares fair. Black-Right-Pointing-Pointer Method for analyzing centralized vs. decentralized disputes. Black-Right-Pointing-Pointer If collective action has less benefits, innovative cost sharing may ensure success.« less

  6. Landscape scale attributes of elk centers of activity in the central Black Hills of South Dakota

    Treesearch

    Cynthia H. Stubblefield; Kerri T. Vierling; Mark A. Rumble

    2006-01-01

    We researched the environmental attributes (n = 28) associated with elk (n = 50) summer range (1 May ­30 Sep) in the central Black Hills of South Dakota, USA, during 1998-­2001. We defined high-use areas or centers of activity as landscapes underlying large concentrations of elk locations resulting from the shared fidelity of...

  7. Solar thermal electricity generation

    NASA Astrophysics Data System (ADS)

    Gasemagha, Khairy Ramadan

    1993-01-01

    This report presents the results of modeling the thermal performance and economic feasibility of large (utility scale) and small solar thermal power plants for electricity generation. A number of solar concepts for power systems applications have been investigated. Each concept has been analyzed over a range of plant power ratings from 1 MW(sub e) to 300 MW(sub e) and over a range of capacity factors from a no-storage case (capacity factor of about 0.25 to 0.30) up to intermediate load capacity factors in the range of 0.46 to 0.60. The solar plant's economic viability is investigated by examining the effect of various parameters on the plant costs (both capital and O & M) and the levelized energy costs (LEC). The cost components are reported in six categories: collectors, energy transport, energy storage, energy conversion, balance of plant, and indirect/contingency costs. Concentrator and receiver costs are included in the collector category. Thermal and electric energy transport costs are included in the energy transport category. Costs for the thermal or electric storage are included in the energy storage category; energy conversion costs are included in the energy conversion category. The balance of plant cost category comprises the structures, land, service facilities, power conditioning, instrumentation and controls, and spare part costs. The indirect/contingency category consists of the indirect construction and the contingency costs. The concepts included in the study are (1) molten salt cavity central receiver with salt storage (PFCR/R-C-Salt); (2) molten salt external central receiver with salt storage (PFCR/R-E-Salt); (3) sodium external central receiver with sodium storage (PFCR/RE-Na); (4) sodium external central receiver with salt storage (PFCR/R-E-Na/Salt); (5) water/steam external central receiver with oil/rock storage (PFCR/R-E-W/S); (6) parabolic dish with stirling engine conversion and lead acid battery storage (PFDR/SLAB); (7) parabolic dish with stirling engine conversion and redox advanced battery storage (PFDR/S-RAB); and (8) parabolic trough with oil/rock storage (LFDR/R-HT-45). Key annual efficiency and economic results of the study are highlighted in tabular format for plant sizes and capacity factor that resulted in the lowest LEC over the analysis range.

  8. Bermuda 2.0: reflections from Santa Cruz.

    PubMed

    Reardon, Jenny; Ankeny, Rachel A; Bangham, Jenny; W Darling, Katherine; Hilgartner, Stephen; Jones, Kathryn Maxson; Shapiro, Beth; Stevens, Hallam

    2016-12-01

    In February 1996, the genome community met in Bermuda to formulate principles for circulating genomic data. Although it is now 20 years since the Bermuda Principles were formulated, they continue to play a central role in shaping genomic and data-sharing practices. However, since 1996, "openness" has become an increasingly complex issue. This commentary seeks to articulate three core challenges data-sharing faces today. © The Authors 2016. Published by Oxford University Press.

  9. KSC-04PD-0251

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. NASA Administrator Sean OKeefe (center) listens to Congressman Tom Feeney (second from left) during a tour of the Central Florida Research Park, near Orlando. At right is U.S. Congressman Dave Weldon. Central Florida leaders are proposing the research park as the site for the new NASA Shared Services Center. The center would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  10. KSC-04PD-0259

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. U.S. Representative Ric Keller (left) listens intently to a presentation proposing the use of the Central Florida Research Park, near Orlando, as the site of NASAs new Shared Services Center. NASA and Florida officials toured the research park as well. Central Florida leaders are proposing the research park as the site for the center, which would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Six sites around the U.S. are under consideration by NASA.

  11. Collaborative Manufacturing for Small-Medium Enterprises

    NASA Astrophysics Data System (ADS)

    Irianto, D.

    2016-02-01

    Manufacturing systems involve decisions concerning production processes, capacity, planning, and control. In a MTO manufacturing systems, strategic decisions concerning fulfilment of customer requirement, manufacturing cost, and due date of delivery are the most important. In order to accelerate the decision making process, research on decision making structure when receiving order and sequencing activities under limited capacity is required. An effective decision making process is typically required by small-medium components and tools maker as supporting industries to large industries. On one side, metal small-medium enterprises are expected to produce parts, components or tools (i.e. jigs, fixture, mold, and dies) with high precision, low cost, and exact delivery time. On the other side, a metal small- medium enterprise may have weak bargaining position due to aspects such as low production capacity, limited budget for material procurement, and limited high precision machine and equipment. Instead of receiving order exclusively, a small-medium enterprise can collaborate with other small-medium enterprise in order to fulfill requirements high quality, low manufacturing cost, and just in time delivery. Small-medium enterprises can share their best capabilities to form effective supporting industries. Independent body such as community service at university can take a role as a collaboration manager. The Laboratory of Production Systems at Bandung Institute of Technology has implemented shared manufacturing systems for small-medium enterprise collaboration.

  12. Shared Decision-Making for Nursing Practice: An Integrative Review.

    PubMed

    Truglio-Londrigan, Marie; Slyer, Jason T

    2018-01-01

    Shared decision-making has received national and international interest by providers, educators, researchers, and policy makers. The literature on shared decision-making is extensive, dealing with the individual components of shared decision-making rather than a comprehensive process. This view of shared decision-making leaves healthcare providers to wonder how to integrate shared decision-making into practice. To understand shared decision-making as a comprehensive process from the perspective of the patient and provider in all healthcare settings. An integrative review was conducted applying a systematic approach involving a literature search, data evaluation, and data analysis. The search included articles from PubMed, CINAHL, the Cochrane Central Register of Controlled Trials, and PsycINFO from 1970 through 2016. Articles included quantitative experimental and non-experimental designs, qualitative, and theoretical articles about shared decision-making between all healthcare providers and patients in all healthcare settings. Fifty-two papers were included in this integrative review. Three categories emerged from the synthesis: (a) communication/ relationship building; (b) working towards a shared decision; and (c) action for shared decision-making. Each major theme contained sub-themes represented in the proposed visual representation for shared decision-making. A comprehensive understanding of shared decision-making between the nurse and the patient was identified. A visual representation offers a guide that depicts shared decision-making as a process taking place during a healthcare encounter with implications for the continuation of shared decisions over time offering patients an opportunity to return to the nurse for reconsiderations of past shared decisions.

  13. Preface

    Treesearch

    David DeYoe

    1999-01-01

    The idea for this workshop began in 1996 when the folks in Quebec, faced with some unappealing fiscal realities that promised to devastate their provincial forest research capacity, held a meeting that convened representatives from research organizations around the world to share their experiences under similar circumstances. The meeting gathered senior research...

  14. Developing regionally specific grazing practices to promote production, profitability, and environmental quality

    USDA-ARS?s Scientific Manuscript database

    Rangelands are valued for their capacity to provide diverse suites of ecosystem services, from food production to carbon storage to biological diversity. Although rangelands worldwide share common characteristics, differences among biogeographic regions result in differences in the types of opportun...

  15. Crucibles of Leadership.

    ERIC Educational Resources Information Center

    Bennis, Warren G.; Thomas, Robert J.

    2002-01-01

    Often, a traumatic event that forces a profound redefinition of the self forges leadership. The stories of a diverse group of business leaders and the "crucible experiences" that shaped them reveal four essential skills: ability to engage others in shared meanings, compelling voice, integrity, and adaptive capacity (applied creativity). (SK)

  16. The natural antibody repertoire of sharks and humans recognizes the potential universe of antigens.

    PubMed

    Adelman, Miranda K; Schluter, Samuel F; Marchalonis, John J

    2004-02-01

    In ancestral sharks, a rapid emergence in the evolution of the immune system occurred, giving jawed-vertebrates the necessary components for the combinatorial immune response (CIR). To compare the natural antibody (NAb) repertoires of the most divergent vertebrates with the capacity to produce antibodies, we isolated NAbs to the same set of antigens by affinity chromatography from two species of Carcharhine sharks and from human polyclonal IgG and IgM antibody preparations. The activities of the affinity-purified anti-T-cell receptor (anti-TCR) NAbs were compared with those of monoclonal anti-TCR NAbs that were generated from a systemic lupus erythematosus patient. We report that sharks and humans, representing the evolutionary extremes of vertebrate species sharing the CIR, have NAbs to human TCRs, Igs, the human senescent cell antigen, and to numerous retroviral antigens, indicating that essential features of the combinatorial repertoire and the capacity to recognize the potential universe of antigens is shared among all jawed-vertebrates.

  17. Shared influence of pathogen and host genetics on a trade-off between latent period and spore production capacity in the wheat pathogen, Puccinia triticina.

    PubMed

    Pariaud, Bénédicte; Berg, Femke; Bosch, Frank; Powers, Stephen J; Kaltz, Oliver; Lannou, Christian

    2013-02-01

    Crop pathogens are notorious for their rapid adaptation to their host. We still know little about the evolution of their life cycles and whether there might be trade-offs between fitness components, limiting the evolutionary potential of these pathogens. In this study, we explored a trade-off between spore production capacity and latent period in Puccinia triticina, a fungal pathogen causing leaf rust on wheat. Using a simple multivariate (manova) technique, we showed that the covariance between the two traits is under shared control of host and pathogen, with contributions from host genotype (57%), pathogen genotype (18.4%) and genotype × genotype interactions (12.5%). We also found variation in sign and strength of genetic correlations for the pathogen, when measured on different host varieties. Our results suggest that these important pathogen life-history traits do not freely respond to directional selection and that precise evolutionary trajectories are contingent on the genetic identity of the interacting host and pathogen.

  18. Oil and gas pipeline construction cost analysis and developing regression models for cost estimation

    NASA Astrophysics Data System (ADS)

    Thaduri, Ravi Kiran

    In this study, cost data for 180 pipelines and 136 compressor stations have been analyzed. On the basis of the distribution analysis, regression models have been developed. Material, Labor, ROW and miscellaneous costs make up the total cost of a pipeline construction. The pipelines are analyzed based on different pipeline lengths, diameter, location, pipeline volume and year of completion. In a pipeline construction, labor costs dominate the total costs with a share of about 40%. Multiple non-linear regression models are developed to estimate the component costs of pipelines for various cross-sectional areas, lengths and locations. The Compressor stations are analyzed based on the capacity, year of completion and location. Unlike the pipeline costs, material costs dominate the total costs in the construction of compressor station, with an average share of about 50.6%. Land costs have very little influence on the total costs. Similar regression models are developed to estimate the component costs of compressor station for various capacities and locations.

  19. Pediatric Brain Tumor Foundation

    MedlinePlus

    ... navigate their brain tumor diagnosis. WATCH AND SHARE Brain tumors and their treatment can be deadly so ... Pediatric Central Nervous System Cancers Read more >> Pediatric Brain Tumor Foundation 302 Ridgefield Court, Asheville, NC 28806 ...

  20. Leadership, Knowledge Sharing, and Creativity: The Key Factors in Nurses' Innovative Behaviors.

    PubMed

    Kim, Sung-Jin; Park, Myonghwa

    2015-12-01

    This study identified the factors that affect the innovative behaviors of nurses at general hospitals based on their individual and organizational characteristics. The predictors of innovative nursing behaviors, such as self-leadership, individual knowledge sharing, creative self-efficacy, organizational knowledge sharing, and innovative organizational cultures, should be explored at individual and organizational level. This study administered a cross-sectional survey to 347 registered nurses working at 6 general hospitals (with >300 beds) in central South Korea. Data were collected using a self-report questionnaire and analyzed using structural equation modeling. Self-leadership, creative self-efficacy, and individual knowledge sharing directly affected individual innovative behaviors. Organizational knowledge sharing indirectly affected individual innovative behaviors, and this effect was mediated by an innovative organizational culture. This study contributes to the knowledge base regarding the effective management of individuals and organizations through innovative behavior; furthermore, it provides future directions for nursing interventions.

  1. Climate Change and Water Infrastructure in Central Asia: adaptation capacities and institutional challenges

    NASA Astrophysics Data System (ADS)

    Abdullaev, Iskandar; Rakhmatullaev, Shavkat

    2014-05-01

    The paper discusses vulnerability areas of water sector in arid Central Asia due to climate change projections with particular focus on adaptation to sustainable operation of physical infrastructure capacities (from legal, institutional and technical aspects). Two types of technical installations are the main focus of this paper, i.e., electrical lift irrigation systems and water reservoirs. The first set of electrical lift infrastructure is strategic for delivering water to water users via pumps, diversion structures, vertical drainage facilities and groundwater boreholes; on the other hand, the primarily task of second set of structures is to accumulate the water resources for sectors of economy. In Central Asia, approximately, 20-50% of irrigation water is lifted, yet major of lift structures are in very poor technical conditions coupled with ever increasing of electricity tariffs. Furthermore, useful volumes capacities of water reservoirs are being severely diminished due to bio-physical geomorphologic processes, improper operational regimes and chronic financing for special in-house sedimentation surveys. Most importantly, the key argument is that irrigation sector should internalize its adaptation efforts, i.e., integrate renewable energy technologies, energy audit programs and lastly design comprehensive investment prioritization processes and programs. Otherwise, water sector will be at great risk for continued provision of fundamental services to the public, food security and industry

  2. Dynamic conversion of solar generated heat to electricity

    NASA Technical Reports Server (NTRS)

    Powell, J. C.; Fourakis, E.; Hammer, J. M.; Smith, G. A.; Grosskreutz, J. C.; Mcbride, E.

    1974-01-01

    The effort undertaken during this program led to the selection of the water-superheated steam (850 psig/900 F) crescent central receiver as the preferred concept from among 11 candidate systems across the technological spectrum of the dynamic conversion of solar generated heat to electricity. The solar power plant designs were investigated in the range of plant capacities from 100 to 1000 Mw(e). The investigations considered the impacts of plant size, collector design, feed-water temperature ratio, heat rejection equipment, ground cover, and location on solar power technical and economic feasibility. For the distributed receiver systems, the optimization studies showed that plant capacities less than 100 Mw(e) may be best. Although the size of central receiver concepts was not parametrically investigated, all indications are that the optimal plant capacity for central receiver systems will be in the range from 50 to 200 Mw(e). Solar thermal power plant site selection criteria and methodology were also established and used to evaluate potentially suitable sites. The result of this effort was to identify a site south of Inyokern, California, as typically suitable for a solar thermal power plant. The criteria used in the selection process included insolation and climatological characteristics, topography, and seismic history as well as water availability.

  3. Legal and regulatory capacity to support the global health security agenda.

    PubMed

    Morhard, Ryan; Katz, Rebecca

    2014-01-01

    On February 13, 2014, 27 nations, along with 3 international organizations, launched the Global Health Security Agenda (GHSA). The intent of GHSA is to accelerate progress in enabling countries around the world to prevent, detect, and respond to public health emergencies-capacities to be achieved through 9 core objectives. Building national, regional, and international capacity includes creating strong legal and regulatory regimes to support national and international capacities to prevent, detect, and respond to public health emergencies. Accordingly, establishing and reinforcing international and national-level legal preparedness is central to advancing elements of each of the 9 objectives of the GHSA.

  4. "I share, therefore I am": personality traits, life satisfaction, and Facebook check-ins.

    PubMed

    Wang, Shaojung Sharon

    2013-12-01

    This study explored whether agreeableness, extraversion, and openness function to influence self-disclosure behavior, which in turn impacts the intensity of checking in on Facebook. A complete path from extraversion to Facebook check-in through self-disclosure and sharing was found. The indirect effect from sharing to check-in intensity through life satisfaction was particularly salient. The central component of check-in is for users to disclose a specific location selectively that has implications on demonstrating their social lives, lifestyles, and tastes, enabling a selective and optimized self-image. Implications on the hyperpersonal model and warranting principle are discussed.

  5. Update on CERN Search based on SharePoint 2013

    NASA Astrophysics Data System (ADS)

    Alvarez, E.; Fernandez, S.; Lossent, A.; Posada, I.; Silva, B.; Wagner, A.

    2017-10-01

    CERN’s enterprise Search solution “CERN Search” provides a central search solution for users and CERN service providers. A total of about 20 million public and protected documents from a wide range of document collections is indexed, including Indico, TWiki, Drupal, SharePoint, JACOW, E-group archives, EDMS, and CERN Web pages. In spring 2015, CERN Search was migrated to a new infrastructure based on SharePoint 2013. In the context of this upgrade, the document pre-processing and indexing process was redesigned and generalised. The new data feeding framework allows to profit from new functionality and it facilitates the long term maintenance of the system.

  6. Using Hazard Functions to Assess Changes in Processing Capacity in an Attentional Cuing Paradigm

    ERIC Educational Resources Information Center

    Wenger, Michael J.; Gibson, Bradley S.

    2004-01-01

    Processing capacity-defined as the relative ability to perform mental work in a unit of time-is a critical construct in cognitive psychology and is central to theories of visual attention. The unambiguous use of the construct, experimentally and theoretically, has been hindered by both conceptual confusions and the use of measures that are at best…

  7. Skidders, Trucking, and Fellers limiting Factors in WV Logging Industry

    Treesearch

    William G. Luppold; Curt C. Hassler; Shawn Grushecky; Shawn Grushecky

    1998-01-01

    Like many states in the Central Appalachian region West Virginia has experienced a continual expansion in primary hardwood processing capacity during the 1990s. In the early part of the decade, hardwood sawmill capacity increased by nearly 40 percent to more than 700 million board feet per year. In the mid and late 1990s, several other primary processing facilities...

  8. Place-Conscious Capacity-Building: A Systemic Model for the Revitalisation and Renewal of Rural Schools and Communities through University-Based Regional Stewardship

    ERIC Educational Resources Information Center

    Johnson, Jerry; Thompson, Aaron; Naugle, Kim

    2009-01-01

    This paper sets forth a model of regional stewardship developed and implemented at a post-compulsory institution serving rural communities in central Appalachia, a region that is among the most impoverished in the United States. The model, termed place-conscious capacity-building, emphasises culturally-responsive methodologies and the strategic…

  9. Combining local and global limitations of visual search.

    PubMed

    Põder, Endel

    2017-04-01

    There are different opinions about the roles of local interactions and central processing capacity in visual search. This study attempts to clarify the problem using a new version of relevant set cueing. A central precue indicates two symmetrical segments (that may contain a target object) within a circular array of objects presented briefly around the fixation point. The number of objects in the relevant segments, and density of objects in the array were varied independently. Three types of search experiments were run: (a) search for a simple visual feature (color, size, and orientation); (b) conjunctions of simple features; and (c) spatial configuration of simple features (rotated Ts). For spatial configuration stimuli, the results were consistent with a fixed global processing capacity and standard crowding zones. For simple features and their conjunctions, the results were different, dependent on the features involved. While color search exhibits virtually no capacity limits or crowding, search for an orientation target was limited by both. Results for conjunctions of features can be partly explained by the results from the respective features. This study shows that visual search is limited by both local interference and global capacity, and the limitations are different for different visual features.

  10. Assessing Clinical Research Capacity in Vietnam: A Framework for Strengthening Capability for Clinical Trials in Developing Countries.

    PubMed

    Kagan, Jonathan; Giang, Dao Duc; Iademarco, Michael F; Phung, Van Tt; Lau, Chuen-Yen; Quang, Nguyen Ngo

    2016-01-01

    Although improving health systems promises important benefits, most developing nations lack the resources to support nationally driven clinical research. Strengthened clinical research capacity can advance national health goals by supporting greater autonomy in aligning research with national priorities. From March through June 2010, we assessed six elements of clinical research capacity in Vietnam: research agenda; clinical investigators and biostatisticians; donors and sponsors; community involvement; scientific, ethical, safety, and quality oversight; and clinical research institutions. Assessments were drawn from interviews with investigators, Ministry of Health staff members, nongovernment organizations, and U.S. Mission staff members, and document review. Observations and recommendations were shared with collaborators. Reassessment in 2015 found growth in the number of clinical trials, improved regulation in human subjects protection and community engagement, and modest advances in research agenda setting. Training and investment in institutions remain challenging. A framework for assessing clinical research capacity can affirm strengths and weaknesses and guide the coordination of capacity-building efforts.

  11. Involving Research Stakeholders in Developing Policy on Sharing Public Health Research Data in Kenya: Views on Fair Process for Informed Consent, Access Oversight, and Community Engagement.

    PubMed

    Jao, Irene; Kombe, Francis; Mwalukore, Salim; Bull, Susan; Parker, Michael; Kamuya, Dorcas; Molyneux, Sassy; Marsh, Vicki

    2015-07-01

    Increased global sharing of public health research data has potential to advance scientific progress but may present challenges to the interests of research stakeholders, particularly in low-to-middle income countries. Policies for data sharing should be responsive to public views, but there is little evidence of the systematic study of these from low-income countries. This qualitative study explored views on fair data-sharing processes among 60 stakeholders in Kenya with varying research experience, using a deliberative approach. Stakeholders' attitudes were informed by perceptions of benefit and concerns for research data sharing, including risks of stigmatization, loss of privacy, and undermining scientific careers and validity, reported in detail elsewhere. In this article, we discuss institutional trust-building processes seen as central to perceptions of fairness in sharing research data in this setting, including forms of community involvement, individual prior awareness and agreement to data sharing, independence and accountability of governance mechanisms, and operating under a national framework. © The Author(s) 2015.

  12. Involvement of the Central Cognitive Mechanism in Word Production in Adults Who Stutter

    ERIC Educational Resources Information Center

    Tsai, Pei-Tzu; Bernstein Ratner, Nan

    2016-01-01

    Purpose: The study examined whether semantic and phonological encoding processes were capacity demanding, involving the central cognitive mechanism, in adults who do and do not stutter (AWS and NS) to better understand the role of cognitive demand in linguistic processing and stuttering. We asked (a) whether the two linguistic processes in AWS are…

  13. Managing the Night Off-Peak Power Demand in the Central Region UPS with Newly Commissioned NPP Capacities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aminov, R. Z.; Pron’, D. M.

    2014-01-15

    The use of hydrogen technologies as a controlled-load consumer based on the newly commissioned base-load nuclear power plants to level out the daily load profile is justified for the Unified Power System (UPS) of the Central Region of Russia, as an example, for the period till 2020.

  14. Using Data Wisely at the System Level

    ERIC Educational Resources Information Center

    Lockwood, Meghan; Dillman, Mary; Boudett, Kathryn Parker

    2017-01-01

    District administrators who want to build capacity for data use in schools may be well-served by starting in the central office. This case study of the Boston Public Schools shows how central office administrators can leverage their own data inquiry cycles to improve the ways they support schools in using data. Using the Data Wise Improvement…

  15. Centralized waste treatment of industrial wastewater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saltzberg, E.R.; Cushnie, G.C. Jr.

    1985-01-01

    Centralized waste treatment (CWT) for industrial wastewater is described in this book. With the CWT approach, industrial firms send their wastes to a common processing plant. The book addresses the engineering and business-related problems that are encountered by private CWT firms, local governments, and industry in creating sufficient CWT capacity to meet the growing demand for CWT services.

  16. Multiprocessor shared-memory information exchange

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Santoline, L.L.; Bowers, M.D.; Crew, A.W.

    1989-02-01

    In distributed microprocessor-based instrumentation and control systems, the inter-and intra-subsystem communication requirements ultimately form the basis for the overall system architecture. This paper describes a software protocol which addresses the intra-subsystem communications problem. Specifically the protocol allows for multiple processors to exchange information via a shared-memory interface. The authors primary goal is to provide a reliable means for information to be exchanged between central application processor boards (masters) and dedicated function processor boards (slaves) in a single computer chassis. The resultant Multiprocessor Shared-Memory Information Exchange (MSMIE) protocol, a standard master-slave shared-memory interface suitable for use in nuclear safety systems, ismore » designed to pass unidirectional buffers of information between the processors while providing a minimum, deterministic cycle time for this data exchange.« less

  17. Framework for Shared Drinking Water Risk Assessment.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowry, Thomas Stephen; Tidwell, Vincent C.; Peplinski, William John

    Central to protecting our nation's critical infrastructure is the development of methodologies for prioritizing action and supporting resource allocation decisions associated with risk-reduction initiatives. Toward this need a web-based risk assessment framework that promotes the anonymous sharing of results among water utilities is demonstrated. Anonymous sharing of results offers a number of potential advantages such as assistance in recognizing and correcting bias, identification of 'unknown, unknowns', self-assessment and benchmarking for the local utility, treatment of shared assets and/or threats across multiple utilities, and prioritization of actions beyond the scale of a single utility. The constructed framework was demonstrated for threemore » water utilities. Demonstration results were then compared to risk assessment results developed using a different risk assessment application by a different set of analysts.« less

  18. Shared decision making in mental health: the importance for current clinical practice.

    PubMed

    Alguera-Lara, Victoria; Dowsey, Michelle M; Ride, Jemimah; Kinder, Skye; Castle, David

    2017-12-01

    We reviewed the literature on shared decision making (regarding treatments in psychiatry), with a view to informing our understanding of the decision making process and the barriers that exist in clinical practice. Narrative review of published English-language articles. After culling, 18 relevant articles were included. Themes identified included models of psychiatric care, benefits for patients, and barriers. There is a paucity of published studies specifically related to antipsychotic medications. Shared decision making is a central part of the recovery paradigm and is of increasing importance in mental health service delivery. The field needs to better understand the basis on which decisions are reached regarding psychiatric treatments. Discrete choice experiments might be useful to inform the development of tools to assist shared decision making in psychiatry.

  19. Optical threshold secret sharing scheme based on basic vector operations and coherence superposition

    NASA Astrophysics Data System (ADS)

    Deng, Xiaopeng; Wen, Wei; Mi, Xianwu; Long, Xuewen

    2015-04-01

    We propose, to our knowledge for the first time, a simple optical algorithm for secret image sharing with the (2,n) threshold scheme based on basic vector operations and coherence superposition. The secret image to be shared is firstly divided into n shadow images by use of basic vector operations. In the reconstruction stage, the secret image can be retrieved by recording the intensity of the coherence superposition of any two shadow images. Compared with the published encryption techniques which focus narrowly on information encryption, the proposed method can realize information encryption as well as secret sharing, which further ensures the safety and integrality of the secret information and prevents power from being kept centralized and abused. The feasibility and effectiveness of the proposed method are demonstrated by numerical results.

  20. Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.

    PubMed

    Cypess, Aaron M; White, Andrew P; Vernochet, Cecile; Schulz, Tim J; Xue, Ruidan; Sass, Christina A; Huang, Tian Liang; Roberts-Toler, Carla; Weiner, Lauren S; Sze, Cathy; Chacko, Aron T; Deschamps, Laura N; Herder, Lindsay M; Truchan, Nathan; Glasgow, Allison L; Holman, Ashley R; Gavrila, Alina; Hasselgren, Per-Olof; Mori, Marcelo A; Molla, Michael; Tseng, Yu-Hua

    2013-05-01

    The imbalance between energy intake and expenditure is the underlying cause of the current obesity and diabetes pandemics. Central to these pathologies is the fat depot: white adipose tissue (WAT) stores excess calories, and brown adipose tissue (BAT) consumes fuel for thermogenesis using tissue-specific uncoupling protein 1 (UCP1). BAT was once thought to have a functional role in rodents and human infants only, but it has been recently shown that in response to mild cold exposure, adult human BAT consumes more glucose per gram than any other tissue. In addition to this nonshivering thermogenesis, human BAT may also combat weight gain by becoming more active in the setting of increased whole-body energy intake. This phenomenon of BAT-mediated diet-induced thermogenesis has been observed in rodents and suggests that activation of human BAT could be used as a safe treatment for obesity and metabolic dysregulation. In this study, we isolated anatomically defined neck fat from adult human volunteers and compared its gene expression, differentiation capacity and basal oxygen consumption to different mouse adipose depots. Although the properties of human neck fat vary substantially between individuals, some human samples share many similarities with classical, also called constitutive, rodent BAT.

  1. Sex differences in social modulation of learning in rats.

    PubMed

    Mikosz, Marta; Nowak, Aleksandra; Werka, Tomasz; Knapska, Ewelina

    2015-12-14

    In its simplest form, empathy can be characterized as the capacity to share the emotional experiences among individuals, a phenomenon known as emotional contagion. Recent research shows that emotional contagion and its adaptive role can be studied in rodents. However, it is not known whether sex differences observed in human empathy extend to its more primitive forms. In the present study, we used a rat model of emotional contagion to compare the behavioral consequences of social transfer of information about threat, and the subsequent neural activation patterns in male and female rats. We found that: (1) males and females display a similar behavioral pattern during the interaction with either a fear-conditioned or a control rat; (2) interaction with a fear-conditioned conspecific positively modulates two-way avoidance learning in male and diestral female rats but not in estral females; and (3) such interaction results in increased c-Fos expression in the central and lateral nuclei of the amygdala and the prelimbic and infralimbic cortex in males, whereas in females no such changes were observed. Collectively, our results point to the occurrence of sex and estrus cycle phase differences in susceptibility to emotional contagion and underlying neuronal activation in rodents.

  2. Sex differences in social modulation of learning in rats

    PubMed Central

    Mikosz, Marta; Nowak, Aleksandra; Werka, Tomasz; Knapska, Ewelina

    2015-01-01

    In its simplest form, empathy can be characterized as the capacity to share the emotional experiences among individuals, a phenomenon known as emotional contagion. Recent research shows that emotional contagion and its adaptive role can be studied in rodents. However, it is not known whether sex differences observed in human empathy extend to its more primitive forms. In the present study, we used a rat model of emotional contagion to compare the behavioral consequences of social transfer of information about threat, and the subsequent neural activation patterns in male and female rats. We found that: (1) males and females display a similar behavioral pattern during the interaction with either a fear-conditioned or a control rat; (2) interaction with a fear-conditioned conspecific positively modulates two-way avoidance learning in male and diestral female rats but not in estral females; and (3) such interaction results in increased c-Fos expression in the central and lateral nuclei of the amygdala and the prelimbic and infralimbic cortex in males, whereas in females no such changes were observed. Collectively, our results point to the occurrence of sex and estrus cycle phase differences in susceptibility to emotional contagion and underlying neuronal activation in rodents. PMID:26655917

  3. The effects of economic and political integration on power plants’ carbon emissions in the post-soviet transition nations

    NASA Astrophysics Data System (ADS)

    Jorgenson, Andrew K.; Longhofer, Wesley; Grant, Don; Sie, Amanda; Giedraitis, Vincentas

    2017-04-01

    The combustion of fossil fuels for electricity generation, which accounts for a significant share of the world’s CO2 emissions, varies by macro-regional context. Here we use multilevel regression modeling techniques to analyze CO2 emissions levels in the year 2009 for 1360 fossil-fuel power plants in the 25 post-Soviet transition nations in Central and Eastern Europe and Eurasia. We find that various facility-level factors are positively associated with plant-level emissions, including plant size, age, heat rate, capacity utilization rate, and coal as the primary fuel source. Results further indicate that plant-level emissions are lower, on average, in the transition nations that joined the European Union (EU), whose market reforms and environmental directives are relevant for emissions reductions. These negative associations between plant-level emissions and EU accession are larger for the nations that joined the EU in 2004 relative to those that joined in 2007. The findings also suggest that export-oriented development is positively associated with plant-level CO2 emissions in the transition nations. Our results highlight the importance in macro-regional assessments of the conjoint effects of political and economic integration for facility-level emissions.

  4. Health Literacy and Atrial Fibrillation: Relevance and Future Directions for Patient-centred Care.

    PubMed

    Aronis, Konstantinos N; Edgar, Brittany; Lin, Wendy; Martins, Maria Auxiliadora Parreiras; Paasche-Orlow, Michael K; Magnani, Jared W

    2017-01-01

    Atrial fibrillation (AF) is a common cardiac arrhythmia with significant clinical outcomes, and is associated with high medical and social costs. AF is complicated for patients because of its specialised terminology, long-term adherence, symptom monitoring, referral to specialty care, array of potential interventions and potential for adversity. Health literacy is a frequently under-recognised, yet fundamental, component towards successful care in AF. Health literacy is defined as the capacity to obtain, process and understand health information, and has had markedly limited study in AF. However, health literacy could contribute to how patients interpret symptoms, navigate care, and participate in treatment evaluation and decision-making. This review aims to summarise the clinical importance and essential relevance of health literacy in AF. We focus here on central aspects of AF care that are most related to self-care, including understanding the symptoms of AF, shared decision-making, adherence and anticoagulation for stroke prevention. We discuss opportunities to enhance AF care based on findings from the literature on health literacy, and identify important gaps. Our overall objective is to articulate the importance and relevance of integrating health literacy in the care of individuals with AF.

  5. Expanding the Horizon: A Journey to Explore and Share Effective Geoscience Research Experiences

    NASA Astrophysics Data System (ADS)

    Bolman, J.

    2013-12-01

    The Indian Natural Resource Science and Engineering Program (INRSEP) has worked diligently over the past 40 + years to ensure the success of Tribal, Indigenous and Underrepresented undergraduate and graduate students in geoscience and natural resources fields of study. Central to this success has been the development of cultural relevant research opportunities directed by Tribal people. The research experiences have been initiated to address culturally relevant challenges on Tribal and non-Tribal lands. It has become critically important to ensure students have multiple research experiences across North America as well as throughout the continent. The INRSEP community has found creating and maintaining relationships with organizations like the Geoscience Alliance, Minorities Striving and Pursuing Higher Degrees of Success (MSPHD's) and the Louis Stokes Alliance for Minority Participation (LSAMP) program has greatly improved the success of students matriculating to graduate STEM programs. These relationships also serve an immense capacity in tracking students, promoting best practices in research development and assessing outcomes. The presentation will highlight lessons learned on how to 1) Develop a diverse cohort or 'community' of student researchers; 2) Evolve intergenerational mentoring processes and outcomes; 3) Tether to related research and programs; and Foster the broader impact of geoscience research and outcomes.

  6. Linking knowledge with action in the pursuit of sustainable water-resources management

    PubMed Central

    Jacobs, Katharine; Lebel, Louis; Buizer, James; Addams, Lee; Matson, Pamela; McCullough, Ellen; Garden, Po; Saliba, George; Finan, Timothy

    2016-01-01

    Managing water for sustainable use and economic development is both a technical and a governance challenge in which knowledge production and sharing play a central role. This article evaluates and compares the role of participatory governance and scientific information in decision-making in four basins in Brazil, Mexico, Thailand, and the United States. Water management institutions in each of the basins have evolved during the last 10–20 years from a relatively centralized water-management structure at the state or national level to a decision structure that involves engaging water users within the basins and the development of participatory processes. This change is consistent with global trends in which states increasingly are expected to gain public acceptance for larger water projects and policy changes. In each case, expanded citizen engagement in identifying options and in decision-making processes has resulted in more complexity but also has expanded the culture of integrated learning. International funding for water infrastructure has been linked to requirements for participatory management processes, but, ironically, this study finds that participatory processes appear to work better in the context of decisions that are short-term and easily adjusted, such as water-allocation decisions, and do not work so well for longer-term, high-stakes decisions regarding infrastructure. A second important observation is that the costs of capacity building to allow meaningful stakeholder engagement in water-management decision processes are not widely recognized. Failure to appreciate the associated costs and complexities may contribute to the lack of successful engagement of citizens in decisions regarding infrastructure. PMID:20080611

  7. Treatment of substance use disorders through the government health facilities: Developments in the "Drug De-addiction Programme" of Ministry of Health and Family Welfare, Government of India.

    PubMed

    Dhawan, Anju; Rao, Ravindra; Ambekar, Atul; Pusp, Amal; Ray, Rajat

    2017-01-01

    Substance use disorder (SUD) is a major problem worldwide, including in India, and contributes significantly to morbidity and mortality. The Ministry of Social Justice and Empowerment, Government of India, addresses the prevention and rehabilitation aspect of substance use through the establishment of "rehabilitation centers" run by nongovernmental organizations. The Drug De-addiction Programme (DDAP) was initiated in 1988 under the Ministry of Health and Family Welfare, Government of India, and was mandated with provision of treatment for SUDs. Through the DDAP, de-addiction centers (DACs) have been established in government hospitals by providing a one-time financial grant by the central government, with the recurring expenses to be borne by the state governments. In addition, some premier institutions as well as DACs from Northeastern region are provided annual recurring grants for their functioning. Capacity building has been a major focus area of DDAP in which nonspecialist medical officers working in government hospitals have been trained, and various training materials have been developed. Another major area of work is the development of "drug abuse monitoring system" to track the pattern of drug use and profile among individuals seeking treatment in the DACs. Monitoring and evaluation exercises carried out show that the existing model of inpatient treatment and of shared responsibility between central and state governments is partially successful. The establishment of drug treatment clinics on pilot basis with a focus on outpatient treatment and direct support from the DDAP for staff as well as for medicines is showing encouraging results.

  8. MAppERS experience: natural processes and preparedness in the societal context

    NASA Astrophysics Data System (ADS)

    Frigerio, Simone; Schenato, Luca; Bossi, Giulia; Mantovani, Matteo; Marcato, Gianluca; Pasuto, Alessandro

    2016-04-01

    Within natural processes responsibilities from central authorities to local levels as first actors of civil protection is a changing pattern. Prevention and preparedness in natural hazards are long-term goals based on capacities of professional volunteers, and improving the awareness of the citizens as local inhabitants. Local people have impacts on their lives but training and involvement towards specific techniques change their role within risk communication and emergency preparedness. A collaborative user environment is useful for emergency response and support in the wake of disasters, feeding updated information on the ground directly to on-site responders. MAppERS (Mobile Application for Emergency Response and Support) is a funded project (2013-2015 Humanitarian Aid and Civil Protection, ECHO A5) based on human role as "crowd-sourced mappers" through smart phone application able to share GPS-localised and detailed parameters. The feedback from testing and the training courses aim to raising public awareness and participation in a networked disaster response. The project implies design and test of smart phone linked with a real-time dashboard platform for rescue services citizens and volunteers of civil protection. Two pilot sites, including trainings on modules functioning control usability and quality of the product. The synchronized platform offers the activity of cloud data collection with a central data dashboard. Information is collected in a context of floods processes, with crowdsourcing action from local population, for proper awareness with own personal flood plan and long-term preparedness. A second context tested pre-emergency actions on field with rescue team, collecting state-of-art and condition of hazards.

  9. Tracing the Potential Flow of Consumer Data: A Network Analysis of Prominent Health and Fitness Apps

    PubMed Central

    Held, Fabian P; Bero, Lisa A

    2017-01-01

    Background A great deal of consumer data, collected actively through consumer reporting or passively through sensors, is shared among apps. Developers increasingly allow their programs to communicate with other apps, sensors, and Web-based services, which are promoted as features to potential users. However, health apps also routinely pose risks related to information leaks, information manipulation, and loss of information. There has been less investigation into the kinds of user data that developers are likely to collect, and who might have access to it. Objective We sought to describe how consumer data generated from mobile health apps might be distributed and reused. We also aimed to outline risks to individual privacy and security presented by this potential for aggregating and combining user data across apps. Methods We purposively sampled prominent health and fitness apps available in the United States, Canada, and Australia Google Play and iTunes app stores in November 2015. Two independent coders extracted data from app promotional materials on app and developer characteristics, and the developer-reported collection and sharing of user data. We conducted a descriptive analysis of app, developer, and user data collection characteristics. Using structural equivalence analysis, we conducted a network analysis of sampled apps’ self-reported sharing of user-generated data. Results We included 297 unique apps published by 231 individual developers, which requested 58 different permissions (mean 7.95, SD 6.57). We grouped apps into 222 app families on the basis of shared ownership. Analysis of self-reported data sharing revealed a network of 359 app family nodes, with one connected central component of 210 app families (58.5%). Most (143/222, 64.4%) of the sampled app families did not report sharing any data and were therefore isolated from each other and from the core network. Fifteen app families assumed more central network positions as gatekeepers on the shortest paths that data would have to travel between other app families. Conclusions This cross-sectional analysis highlights the possibilities for user data collection and potential paths that data is able to travel among a sample of prominent health and fitness apps. While individual apps may not collect personally identifiable information, app families and the partners with which they share data may be able to aggregate consumer data, thus achieving a much more comprehensive picture of the individual consumer. The organizations behind the centrally connected app families represent diverse industries, including apparel manufacturers and social media platforms that are not traditionally involved in health or fitness. This analysis highlights the potential for anticipated and voluntary but also possibly unanticipated and involuntary sharing of user data, validating privacy and security concerns in mobile health. PMID:28659254

  10. Centralized Planning for Multiple Exploratory Robots

    NASA Technical Reports Server (NTRS)

    Estlin, Tara; Rabideau, Gregg; Chien, Steve; Barrett, Anthony

    2005-01-01

    A computer program automatically generates plans for a group of robotic vehicles (rovers) engaged in geological exploration of terrain. The program rapidly generates multiple command sequences that can be executed simultaneously by the rovers. Starting from a set of high-level goals, the program creates a sequence of commands for each rover while respecting hardware constraints and limitations on resources of each rover and of hardware (e.g., a radio communication terminal) shared by all the rovers. First, a separate model of each rover is loaded into a centralized planning subprogram. The centralized planning software uses the models of the rovers plus an iterative repair algorithm to resolve conflicts posed by demands for resources and by constraints associated with the all the rovers and the shared hardware. During repair, heuristics are used to make planning decisions that will result in solutions that will be better and will be found faster than would otherwise be possible. In particular, techniques from prior solutions of the multiple-traveling- salesmen problem are used as heuristics to generate plans in which the paths taken by the rovers to assigned scientific targets are shorter than they would otherwise be.

  11. Unconstrained Capacities of Quantum Key Distribution and Entanglement Distillation for Pure-Loss Bosonic Broadcast Channels.

    PubMed

    Takeoka, Masahiro; Seshadreesan, Kaushik P; Wilde, Mark M

    2017-10-13

    We consider quantum key distribution (QKD) and entanglement distribution using a single-sender multiple-receiver pure-loss bosonic broadcast channel. We determine the unconstrained capacity region for the distillation of bipartite entanglement and secret key between the sender and each receiver, whenever they are allowed arbitrary public classical communication. A practical implication of our result is that the capacity region demonstrated drastically improves upon rates achievable using a naive time-sharing strategy, which has been employed in previously demonstrated network QKD systems. We show a simple example of a broadcast QKD protocol overcoming the limit of the point-to-point strategy. Our result is thus an important step toward opening a new framework of network channel-based quantum communication technology.

  12. Crowdsourcing: Global search and the twisted roles of consumers and producers.

    PubMed

    Bauer, Robert M; Gegenhuber, Thomas

    2015-09-01

    Crowdsourcing spreads and morphs quickly, shaping areas as diverse as creating, organizing, and sharing knowledge; producing digital artifacts; providing services involving tangible assets; or monitoring and evaluating. Crowdsourcing as sourcing by means of 'global search' yields four types of values for sourcing actors: creative expertise, critical items, execution capacity, and bargaining power. It accesses cheap excess capacities at the work realm's margins, channeling them toward production. Provision and utilization of excess capacities rationalize society while intimately connecting to a broader societal trend twisting consumers' and producers' roles: leading toward 'working consumers' and 'consuming producers' and shifting power toward the latter. Similarly, marketers using crowdsourcing's look and feel to camouflage traditional approaches to bringing consumers under control preserve producer power.

  13. Analysis of Requirements of On-Line Network Cataloging Services for Small, Academic, Public, School and Other Libraries: A Demonstration Project using the OCLC System. Final Report.

    ERIC Educational Resources Information Center

    Markuson, Barbara Evans

    This report results from a project using the OCLC system to provide catalog services to small libraries. Alternatives described include: centralized cataloging, centralized book processing, sharing of OCLC terminals, and use of dial-up terminals. The OCLC data base was found useful for all types of small libraries. It is recommended that network…

  14. About opportunities of the sharing of city infrastructure centralized warmly - and water supply

    NASA Astrophysics Data System (ADS)

    Zamaleev, M. M.; Gubin, I. V.; Sharapov, V. I.

    2017-11-01

    It is shown that joint use of engineering infrastructure of centralized heat and water supply of consumers will be the cost-efficient decision for municipal services of the city. The new technology for regulated heating of drinking water in the condenser of steam turbines of combined heat and power plant is offered. Calculation of energy efficiency from application of new technology is executed.

  15. Determination of Predominance of Influenza Virus Strains in the Americas.

    PubMed

    Azziz-Baumgartner, Eduardo; Garten, Rebecca J; Palekar, Rakhee; Cerpa, Mauricio; Mirza, Sara; Ropero, Alba Maria; Palomeque, Francisco S; Moen, Ann; Bresee, Joseph; Shaw, Michael; Widdowson, Marc-Alain

    2015-07-01

    During 2001-2014, predominant influenza A(H1N1) and A(H3N2) strains in South America predominated in all or most subsequent influenza seasons in Central and North America. Predominant A(H1N1) and A(H3N2) strains in North America predominated in most subsequent seasons in Central and South America. Sharing data between these subregions may improve influenza season preparedness.

  16. KENNEDY SPACE CENTER, FLA. - Congressman Dave Weldon listens to a presentation about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. Six sites around the U.S. are under consideration for location of the Center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Others attending the presentation included Congressman Tom Feeney, U.S. Representative Ric Keller, U.S. Senator Bill Nelson, Center Director Jim Kennedy and Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - Congressman Dave Weldon listens to a presentation about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. Six sites around the U.S. are under consideration for location of the Center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus. Others attending the presentation included Congressman Tom Feeney, U.S. Representative Ric Keller, U.S. Senator Bill Nelson, Center Director Jim Kennedy and Pamella J. Dana, Ph.D., director, Office of Tourism, Trade, and Economic Development in Florida.

  17. KENNEDY SPACE CENTER, FLA. - NASA and government officials are gathered to hear about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. Seated at right are Lisa Malone, director of KSC External Affairs, and Joel Wells, with the Government Relations Office. Fourth from right is Jim Jennings, NASA deputy associate administrator for institutions and asset management. Six sites around the U.S. are under consideration for the center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA and government officials are gathered to hear about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. Seated at right are Lisa Malone, director of KSC External Affairs, and Joel Wells, with the Government Relations Office. Fourth from right is Jim Jennings, NASA deputy associate administrator for institutions and asset management. Six sites around the U.S. are under consideration for the center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus.

  18. Mobile Element Evolution Playing Jigsaw—SINEs in Gastropod and Bivalve Mollusks

    PubMed Central

    Matetovici, Irina; Sajgo, Szilard; Ianc, Bianca; Ochis, Cornelia; Bulzu, Paul; Popescu, Octavian; Damert, Annette

    2016-01-01

    SINEs (Short INterspersed Elements) are widely distributed among eukaryotes. Some SINE families are organized in superfamilies characterized by a shared central domain. These central domains are conserved across species, classes, and even phyla. Here we report the identification of two novel such superfamilies in the genomes of gastropod and bivalve mollusks. The central conserved domain of the first superfamily is present in SINEs in Caenogastropoda and Vetigastropoda as well as in all four subclasses of Bivalvia. We designated the domain MESC (Romanian for MElc—snail and SCoica—mussel) because it appears to be restricted to snails and mussels. The second superfamily is restricted to Caenogastropoda. Its central conserved domain—Snail—is related to the Nin-DC domain. Furthermore, we provide evidence that a 40-bp subdomain of the SINE V-domain is conserved in SINEs in mollusks and arthropods. It is predicted to form a stable stem-loop structure that is preserved in the context of the overall SINE RNA secondary structure in invertebrates. Our analysis also recovered short retrotransposons with a Long INterspersed Element (LINE)-derived 5′ end. These share the body and/or the tail with transfer RNA (tRNA)-derived SINEs within and across species. Finally, we identified CORE SINEs in gastropods and bivalves—extending the distribution range of this superfamily. PMID:26739168

  19. 75 FR 29725 - Mid-Atlantic Fishery Management Council; Public Hearings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... management process; the biological and socio-economic outcomes of a catch share system and how such outcomes depend on specific program design features; the possible need for changes to existing information...) fisheries and that uncontrolled activation of latent capacity could cause negative economic effects for...

  20. A Solid Foundation: Key Capacities of Construction Pre-Apprenticeship Programs

    ERIC Educational Resources Information Center

    Helmer, Matt; Blair, Amy; Gerber, Allison

    2012-01-01

    This publication shares research from site visits conducted to construction pre-apprenticeship programs in Baltimore, Hartford, Milwaukee and Portland (OR). Findings from the site visits, which included interviews and focus groups with pre-apprenticeship program staff, public officials, philanthropic leaders, construction industry leaders and…

  1. 47 CFR 101.521 - Spectrum utilization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... applicants for DEMS frequencies in the 10.6 GHz band must submit as part of the original application a... contain detailed descriptions of the modulation method, the channel time sharing method, any error detecting and/or correcting codes, any spatial frequency reuse system and the total data throughput capacity...

  2. Contributing Meaning to Research in Developmental Disabilities: Integrating Participatory Action and Methodological Rigor

    ERIC Educational Resources Information Center

    Powers, Laurie E.

    2017-01-01

    Action research approaches reflecting power sharing by academic and community researchers, full engagement of community partners across all study phases, and ongoing commitment to partnership and capacity building have been increasingly embraced, particularly in research affecting marginalized populations. Findings suggest action research…

  3. Optical memories in digital computing

    NASA Technical Reports Server (NTRS)

    Alford, C. O.; Gaylord, T. K.

    1979-01-01

    High capacity optical memories with relatively-high data-transfer rate and multiport simultaneous access capability may serve as basis for new computer architectures. Several computer structures that might profitably use memories are: a) simultaneous record-access system, b) simultaneously-shared memory computer system, and c) parallel digital processing structure.

  4. Trans-Pacific RAD-Seq population genomics confirms introgressive hybridization in Eastern Pacific Pocillopora corals.

    PubMed

    Combosch, David J; Vollmer, Steven V

    2015-07-01

    Discrepancies between morphology-based taxonomy and phylogenetic systematics are common in Scleractinian corals. In Pocillopora corals, nine recently identified genetic lineages disagree fundamentally with the 17 recognized Pocillopora species, including 5 major Indo-Pacific reef-builders. Pocillopora corals hybridize in the Tropical Eastern Pacific, so it is possible that some of the disagreement between the genetics and taxonomy may be due to introgressive hybridization. Here we used 6769 genome-wide SNPs from Restriction-site Associated DNA Sequencing (RAD-Seq) to conduct phylogenomic comparisons among three common, Indo-Pacific Pocillopora species - P. damicornis, P. eydouxi and P. elegans - within and between populations in the Tropical Eastern Pacific (TEP) and the Central Pacific. Genome-wide RAD-Seq comparisons of Central and TEP Pocillopora confirm that the morphospecies P. damicornis, P. eydouxi and P. elegans are not monophyletic, but instead fall into three distinct genetic groups. However, hybrid samples shared fixed alleles with their respective parental species and, even without strict monophyly, P. damicornis share a common set of 33 species-specific alleles across the Pacific. RAD-Seq data confirm the pattern of one-way introgressive hybridization among TEP Pocillopora, suggesting that introgression may play a role in generating shared, polyphyletic lineages among currently recognized Pocillopora species. Levels of population differentiation within genetic lineages indicate significantly higher levels of population differentiation in the Tropical Eastern Pacific than in the Central West Pacific. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Private practice outcomes: validated outcomes data collection in private practice.

    PubMed

    Goldstein, Jack

    2010-10-01

    Improved patient care is related to validated outcome measures requiring the collection of three distinct data types: (1) demographics; (2) patient outcome measures; and (3) physician treatment. Previous impediments to widespread data collection have been: cost, office disruption, personnel requirements, physician motivation, data integration, and security. There are currently few means to collect data to be used for collaborative analysis. We therefore developed an inexpensive, patient-centric mechanism to reduce redundant data entry, limiting cost and personnel requirements. Using an intuitive touch-screen kiosk interface program, all data elements have been captured in a private practice setting since 2000. Developed for small to medium sized offices, this is scalable to larger organizations. Questionnaire navigation is patient driven, with demographics shared with EMR and billing systems. Integration of billing and EMR with outcomes minimizes cost and personnel time. Data are deidentified locally and may be centrally shared. Since data are entered by the patients, minimal personnel costs are incurred. Physician disincentives are minimized with cost reduction, time savings and ease of use. To date, we have collected high level data on most total joint patients, with excellent patient compliance. By addressing impediments to broad application, we may enable widespread local data collection in all practice settings. Data may be shared centrally, allowing comparative effectiveness research to become a reality. Future success will require broad physician participation, uniformity of data collected, and designation of a central site for receipt of data and its collaborative comparative analysis.

  6. A BASELINE PROFILE OF ASBESTOS IN THE US-AFFILIATED PACIFIC ISLANDS

    PubMed Central

    David, Annette M.; Ogawa, Hisashi; Takahashi, Ken

    2013-01-01

    Asbestos is a recognized occupational and environmental hazard in the Asia-Pacific Region, yet information regarding asbestos consumption, exposure and asbestos-related diseases in the US affiliated Pacific Islands (USAPIs) is scarce and the situation regarding asbestos in these islands, particularly with regards to disease burden, surveillance and health care capacity, is not well understood. Searching through scientific and “grey” literature and interviews with local cancer registry personnel and health professionals yielded no published data but sufficient indirect evidence of past and ongoing asbestos exposure, documented cases of mesothelioma and asbestosis, and minimal capacity for preventing and recognizing asbestos-related illnesses. The relatively low levels of capacity and resources within the USAPIs can impede regional progress in asbestos prevention and highlight the need for an integrated regional approach to address these data and capacity gaps. A regional mechanism to share expertise and resources and facilitate technical assistance to the USAPIs is urgently needed. PMID:22550694

  7. Interaction dynamics: The case of the water sector skills plan in South Africa.

    PubMed

    Moyo, Laurane; Wehn, Uta

    2017-02-01

    Despite extensive and continuous efforts to strengthen the capacity of people, organizations and institutions, there is evidence of an increasing gap between the existing and required capacities within the water sector. Consensus seems to be emerging regarding the need for national strategies to improve water sector capacity development. This paper analyses the dynamics of actors' interactions and their characteristics (motivation, cognition and power) during the formulation and implementation of a specific capacity development strategy, namely the Water Sector Skills Plan (SSP) in South Africa. Based on the Contextual Interactive Theory and empirical findings, our analysis indicates slow progression and challenges with implementing the SSP, mainly due to the lack of consultation with key stakeholders during the formulation stage, a lack of data sharing among the target group (the Sector Education Training Authorities), and a lack of capacities within the key implementing organizations. These policy dynamics need to be taken into account when advocating for national capacity development strategies as a solution for challenges with water sector capacity development. The paper proposes the recommendations that are of relevance for the SSP as well as similar initiatives in other countries. Copyright © 2016. Published by Elsevier Ltd.

  8. Dissecting the link between the enzymatic activity and the SaPI inducing capacity of the phage 80α dUTPase.

    PubMed

    Alite, Christian; Humphrey, Suzanne; Donderis, Jordi; Maiques, Elisa; Ciges-Tomas, J Rafael; Penadés, José R; Marina, Alberto

    2017-09-11

    The trimeric staphylococcal phage-encoded dUTPases (Duts) are signalling molecules that induce the cycle of some Staphylococcal pathogenicity islands (SaPIs) by binding to the SaPI-encoded Stl repressor. To perform this regulatory role, these Duts require an extra motif VI, as well as the Dut conserved motifs IV and V. While the apo form of Dut is required for the interaction with the Stl repressor, usually only those Duts with normal enzymatic activity can induce the SaPI cycle. To understand the link between the enzymatic activities and inducing capacities of the Dut protein, we analysed the structural, biochemical and physiological characteristics of the Dut80α D95E mutant, which loses the SaPI cycle induction capacity despite retaining enzymatic activity. Asp95 is located at the threefold central channel of the trimeric Dut where it chelates a divalent ion. Here, using state-of-the-art techniques, we demonstrate that D95E mutation has an epistatic effect on the motifs involved in Stl binding. Thus, ion binding in the central channel correlates with the capacity of motif V to twist and order in the SaPI-inducing disposition, while the tip of motif VI is disturbed. These alterations in turn reduce the affinity for the Stl repressor and the capacity to induce the SaPI cycle.

  9. Heat capacity of a self-gravitating spherical shell of radiations

    NASA Astrophysics Data System (ADS)

    Kim, Hyeong-Chan

    2017-10-01

    We study the heat capacity of a static system of self-gravitating radiations analytically in the context of general relativity. To avoid the complexity due to a conical singularity at the center, we excise the central part and replace it with a regular spherically symmetric distribution of matters of which specifications we are not interested in. We assume that the mass inside the inner boundary and the locations of the inner and the outer boundaries are given. Then, we derive a formula relating the variations of physical parameters at the outer boundary with those at the inner boundary. Because there is only one free variation at the inner boundary, the variations at the outer boundary are related, which determines the heat capacity. To get an analytic form for the heat capacity, we use the thermodynamic identity δ Srad=β δ Mrad additionally, which is derived from the variational relation of the entropy formula with the restriction that the mass inside the inner boundary does not change. Even if the radius of the inner boundary of the shell goes to zero, in the presence of a central conical singularity, the heat capacity does not go to the form of the regular sphere. An interesting discovery is that another legitimate temperature can be defined at the inner boundary which is different from the asymptotic one β-1.

  10. International Health Regulations (2005) and the U.S. Department of Defense: Building Core Capacities on a Foundation of Partnership and Trust

    DTIC Science & Technology

    2010-12-03

    with the CDC’s Central America and Panama Center, the U.S. Army Public Health Command Region–South (PHCR-South) provided laboratory tech- nical...Introduction and background Th e central focus of disease surveillance systems is the early identifi cation of infectious disease outbreaks in...been leveraged by AFHSC- GEIS for the purpose of disease surveillance and response through a growing network of centrally funded partners (Figure 1

  11. Land Cover Analysis of Temperate Asia

    NASA Technical Reports Server (NTRS)

    Justice, Chris

    1998-01-01

    Satellite data from the advanced very high resolution radiometer (AVHRR) instrument were used to produce a general land cover distribution of temperate Asia (referred to hence as Central Asia) from 1982, starting with the NOAA-7 satellite, and continuing through 1991, ending with the NOAA-11 satellite. Emphasis was placed upon delineating the and and semi-arid zones of Central Asia (largely Mongolia and adjacent areas), mapping broad categories of aggregated land cover, and upon studying photosynthetic capacity increases in Central Asia from 1982 to 1991.

  12. Central control of body temperature

    PubMed Central

    Morrison, Shaun F.

    2016-01-01

    Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains body temperature during environmental temperature challenges and alters body temperature during the inflammatory response and behavioral states and in response to declining energy homeostasis. This review summarizes the central nervous system circuit mechanisms controlling the principal thermoeffectors for body temperature regulation: cutaneous vasoconstriction regulating heat loss and shivering and brown adipose tissue for thermogenesis. The activation of these thermoeffectors is regulated by parallel but distinct efferent pathways within the central nervous system that share a common peripheral thermal sensory input. The model for the neural circuit mechanism underlying central thermoregulatory control provides a useful platform for further understanding of the functional organization of central thermoregulation, for elucidating the hypothalamic circuitry and neurotransmitters involved in body temperature regulation, and for the discovery of novel therapeutic approaches to modulating body temperature and energy homeostasis. PMID:27239289

  13. Central control of body temperature.

    PubMed

    Morrison, Shaun F

    2016-01-01

    Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains body temperature during environmental temperature challenges and alters body temperature during the inflammatory response and behavioral states and in response to declining energy homeostasis. This review summarizes the central nervous system circuit mechanisms controlling the principal thermoeffectors for body temperature regulation: cutaneous vasoconstriction regulating heat loss and shivering and brown adipose tissue for thermogenesis. The activation of these thermoeffectors is regulated by parallel but distinct efferent pathways within the central nervous system that share a common peripheral thermal sensory input. The model for the neural circuit mechanism underlying central thermoregulatory control provides a useful platform for further understanding of the functional organization of central thermoregulation, for elucidating the hypothalamic circuitry and neurotransmitters involved in body temperature regulation, and for the discovery of novel therapeutic approaches to modulating body temperature and energy homeostasis.

  14. Faunistic Composition, Ecological Properties and Zoogeographical Composition of the Family Elateridae (Coleoptera) of the Central Anatolian Region of Turkey

    PubMed Central

    Kabalak, Mahmut; Sert, Osman

    2011-01-01

    The focus of this study was to understand the faunistic composition, ecological properties and zoogeographical composition of Elateridae (Coleoptera) of the Central Anatolian region. 72 species belonging to seven subfamilies and 25 genera were identified. The major part of the Elateridae fauna of the Central Anatolian region is formed by the subfamilies Elaterinae and Cardiophorinae. The genus Cardiophorus was the most species-rich genus. The species composition of the Elateridae fauna of the Central Anatolian region is partially consistent with known Elateridae fauna of Turkey. The Central Anatolian region shares most species with the European part of the Western Palaearctic as does the Elateridae fauna of Turkey. Detailed localities of nine species are given for the first time for Turkey, with emphasis on the Central Anatolian region. PMID:21864150

  15. A Public Health Preparedness Logic Model: Assessing Preparedness for Cross-border Threats in the European Region

    PubMed Central

    Nelson, Christopher; Savoia, Elena; Ljungqvist, Irina; Ciotti, Massimo

    2017-01-01

    Improving preparedness in the European region requires a clear understanding of what European Union (EU) member states should be able to do, whether acting internally or in cooperation with each other or the EU and other multilateral organizations. We have developed a preparedness logic model that specifies the aims and objectives of public health preparedness, as well as the response capabilities and preparedness capacities needed to achieve them. The capabilities, which describe the ability to effectively use capacities to identify, characterize, and respond to emergencies, are organized into 5 categories. The first 3 categories—(1) assessment; (2) policy development, adaptation, and implementation; and (3) prevention and treatment services in the health sector—represent what the public health system must accomplish to respond effectively. The fourth and fifth categories represent a series of interrelated functions needed to ensure that the system fulfills its assessment, policy development, and prevention and treatment roles: (4) coordination and communication regards information sharing within the public health system, incident management, and leadership, and (5) emergency risk communication focuses on communication with the public. This model provides a framework for identifying what to measure in capacity inventories, exercises, critical incident analyses, and other approaches to assessing public health emergency preparedness, not how to measure them. Focusing on a common set of capacities and capabilities to measure allows for comparisons both over time and between member states, which can enhance learning and sharing results and help identify both strengths and areas for improvement of public health emergency preparedness in the EU. PMID:29058967

  16. Common capacity-limited neural mechanisms of selective attention and spatial working memory encoding

    PubMed Central

    Fusser, Fabian; Linden, David E J; Rahm, Benjamin; Hampel, Harald; Haenschel, Corinna; Mayer, Jutta S

    2011-01-01

    One characteristic feature of visual working memory (WM) is its limited capacity, and selective attention has been implicated as limiting factor. A possible reason why attention constrains the number of items that can be encoded into WM is that the two processes share limited neural resources. Functional magnetic resonance imaging (fMRI) studies have indeed demonstrated commonalities between the neural substrates of WM and attention. Here we investigated whether such overlapping activations reflect interacting neural mechanisms that could result in capacity limitations. To independently manipulate the demands on attention and WM encoding within one single task, we combined visual search and delayed discrimination of spatial locations. Participants were presented with a search array and performed easy or difficult visual search in order to encode one, three or five positions of target items into WM. Our fMRI data revealed colocalised activation for attention-demanding visual search and WM encoding in distributed posterior and frontal regions. However, further analysis yielded two patterns of results. Activity in prefrontal regions increased additively with increased demands on WM and attention, indicating regional overlap without functional interaction. Conversely, the WM load-dependent activation in visual, parietal and premotor regions was severely reduced during high attentional demand. We interpret this interaction as indicating the sites of shared capacity-limited neural resources. Our findings point to differential contributions of prefrontal and posterior regions to the common neural mechanisms that support spatial WM encoding and attention, providing new imaging evidence for attention-based models of WM encoding. PMID:21781193

  17. A Public Health Preparedness Logic Model: Assessing Preparedness for Cross-border Threats in the European Region.

    PubMed

    Stoto, Michael A; Nelson, Christopher; Savoia, Elena; Ljungqvist, Irina; Ciotti, Massimo

    Improving preparedness in the European region requires a clear understanding of what European Union (EU) member states should be able to do, whether acting internally or in cooperation with each other or the EU and other multilateral organizations. We have developed a preparedness logic model that specifies the aims and objectives of public health preparedness, as well as the response capabilities and preparedness capacities needed to achieve them. The capabilities, which describe the ability to effectively use capacities to identify, characterize, and respond to emergencies, are organized into 5 categories. The first 3 categories-(1) assessment; (2) policy development, adaptation, and implementation; and (3) prevention and treatment services in the health sector-represent what the public health system must accomplish to respond effectively. The fourth and fifth categories represent a series of interrelated functions needed to ensure that the system fulfills its assessment, policy development, and prevention and treatment roles: (4) coordination and communication regards information sharing within the public health system, incident management, and leadership, and (5) emergency risk communication focuses on communication with the public. This model provides a framework for identifying what to measure in capacity inventories, exercises, critical incident analyses, and other approaches to assessing public health emergency preparedness, not how to measure them. Focusing on a common set of capacities and capabilities to measure allows for comparisons both over time and between member states, which can enhance learning and sharing results and help identify both strengths and areas for improvement of public health emergency preparedness in the EU.

  18. Sharing resources: opportunities for smaller primary care practices to increase their capacity for patient care. Findings from the 2009 Commonwealth Fund International Health Policy Survey of Primary Care Physicians.

    PubMed

    Fryer, Ashley-Kay; Doty, Michelle M; Audet, Anne-Marie J

    2011-03-01

    Most Americans get their health care in small physician practices. Yet, small practice settings are often unable to provide the same range of services or partici­pate in quality improvement initiatives as large practices because they lack the staff, infor­mation technology, and office systems. One promising strategy is to share clinical sup­port services and information systems with other practices. New findings from the 2009 Commonwealth Fund International Health Policy Survey of Primary Care Physicians suggest smaller practices that share resources are more likely than those without shared resources to have advanced electronic medical records and health information technology, routinely track and manage patient information, have after-hours care arrangements, and engage in quality monitoring and benchmarking. This issue brief highlights strategies that can increase resources among small- and medium-sized practices and efforts supported by states, the private sector, and the Affordable Care Act that encourage the expansion of shared-resource models.

  19. Adapted shared reading at school for minimally verbal students with autism.

    PubMed

    Mucchetti, Charlotte A

    2013-05-01

    Almost nothing is known about the capacity of minimally verbal students with autism to develop literacy skills. Shared reading is a regular practice in early education settings and is widely thought to encourage language and literacy development. There is some evidence that children with severe disabilities can be engaged in adapted shared reading activities. The current study examines the impact of teacher-led adapted shared reading activities on engagement and story comprehension in minimally verbal 5-6-year-old children with autism using a multiple baseline/alternating treatment design. Four students and three teachers participated. Teachers conducted adapted shared reading activities with modified books (visual supports, three-dimensional objects, simplified text) and used specific strategies for increasing student engagement. Student performance during adapted activities was compared to performance during standard shared reading sessions. All four students showed increased story comprehension and engagement during adapted shared reading. Average percentage of session engaged was 87%-100% during adapted sessions, compared with 41%-52% during baseline. Average number of correct responses to story comprehension questions was 4.2-4.8 out of 6 during adapted sessions compared with 1.2-2 during baseline. Visual supports, tactile objects, and specific teaching strategies offer ways for minimally verbal students to meaningfully participate in literacy activities. Future research should investigate adapted shared reading activities implemented classroom-wide as well as joint engagement, language, and literacy outcomes after using such activities over time.

  20. Food Security Monitoring via Mobile Data Collection and Remote Sensing: Results from the Central African Republic

    PubMed Central

    Enenkel, Markus; See, Linda; Karner, Mathias; Álvarez, Mònica; Rogenhofer, Edith; Baraldès-Vallverdú, Carme; Lanusse, Candela; Salse, Núria

    2015-01-01

    The Central African Republic is one of the world’s most vulnerable countries, suffering from chronic poverty, violent conflicts and weak disaster resilience. In collaboration with Doctors without Borders/Médecins Sans Frontières (MSF), this study presents a novel approach to collect information about socio-economic vulnerabilities related to malnutrition, access to resources and coping capacities. The first technical test was carried out in the North of the country (sub-prefecture Kabo) in May 2015. All activities were aimed at the investigation of technical feasibility, not at operational data collection, which requires a random sampling strategy. At the core of the study is an open-source Android application named SATIDA COLLECT that facilitates rapid and simple data collection. All assessments were carried out by local MSF staff after they had been trained for one day. Once a mobile network is available, all assessments can easily be uploaded to a database for further processing and trend analysis via MSF in-house software. On one hand, regularly updated food security assessments can complement traditional large-scale surveys, whose completion can take up to eight months. Ideally, this leads to a gain in time for disaster logistics. On the other hand, recording the location of every assessment via the smart phones’ GPS receiver helps to analyze and display the coupling between drought risk and impacts over many years. Although the current situation in the Central African Republic is mostly related to violent conflict it is necessary to consider information about drought risk, because climatic shocks can further disrupt the already vulnerable system. SATIDA COLLECT can easily be adapted to local conditions or other applications, such as the evaluation of vaccination campaigns. Most importantly, it facilitates the standardized collection of information without pen and paper, as well as straightforward sharing of collected data with the MSF headquarters or other aid organizations. PMID:26581042

  1. Providers' perspectives on inbound medical tourism in Central America and the Caribbean: factors driving and inhibiting sector development and their health equity implications.

    PubMed

    Johnston, Rory; Crooks, Valorie A; Cerón, Alejandro; Labonté, Ronald; Snyder, Jeremy; Núñez, Emanuel O; Flores, Walter G

    2016-01-01

    Many governments and health care providers worldwide are enthusiastic to develop medical tourism as a service export. Despite the popularity of this policy uptake, there is relatively little known about the specific local factors prospectively motivating and informing development of this sector. To identify common social, economic, and health system factors shaping the development of medical tourism in three Central American and Caribbean countries and their health equity implications. In-depth, semi-structured interviews were conducted in Mexico, Guatemala, and Barbados with 150 health system stakeholders. Participants were recruited from private and public sectors working in various fields: trade and economic development, health services delivery, training and administration, and civil society. Transcribed interviews were coded using qualitative data management software, and thematic analysis was used to identify cross-cutting issues regarding the drivers and inhibitors of medical tourism development. Four common drivers of medical tourism development were identified: 1) unused capacity in existing private hospitals, 2) international portability of health insurance, vis-a-vis international hospital accreditation, 3) internationally trained physicians as both marketable assets and industry entrepreneurs, and 4) promotion of medical tourism by public export development corporations. Three common inhibitors for the development of the sector were also identified: 1) the high expense of market entry, 2) poor sector-wide planning, and 3) structural socio-economic issues such as insecurity or relatively high business costs and financial risks. There are shared factors shaping the development of medical tourism in Central America and the Caribbean that help explain why it is being pursued by many hospitals and governments in the region. Development of the sector is primarily being driven by public investment promotion agencies and the private health sector seeking economic benefits with limited consideration and planning for the health equity concerns medical tourism raises.

  2. Food Security Monitoring via Mobile Data Collection and Remote Sensing: Results from the Central African Republic.

    PubMed

    Enenkel, Markus; See, Linda; Karner, Mathias; Álvarez, Mònica; Rogenhofer, Edith; Baraldès-Vallverdú, Carme; Lanusse, Candela; Salse, Núria

    2015-01-01

    The Central African Republic is one of the world's most vulnerable countries, suffering from chronic poverty, violent conflicts and weak disaster resilience. In collaboration with Doctors without Borders/Médecins Sans Frontières (MSF), this study presents a novel approach to collect information about socio-economic vulnerabilities related to malnutrition, access to resources and coping capacities. The first technical test was carried out in the North of the country (sub-prefecture Kabo) in May 2015. All activities were aimed at the investigation of technical feasibility, not at operational data collection, which requires a random sampling strategy. At the core of the study is an open-source Android application named SATIDA COLLECT that facilitates rapid and simple data collection. All assessments were carried out by local MSF staff after they had been trained for one day. Once a mobile network is available, all assessments can easily be uploaded to a database for further processing and trend analysis via MSF in-house software. On one hand, regularly updated food security assessments can complement traditional large-scale surveys, whose completion can take up to eight months. Ideally, this leads to a gain in time for disaster logistics. On the other hand, recording the location of every assessment via the smart phones' GPS receiver helps to analyze and display the coupling between drought risk and impacts over many years. Although the current situation in the Central African Republic is mostly related to violent conflict it is necessary to consider information about drought risk, because climatic shocks can further disrupt the already vulnerable system. SATIDA COLLECT can easily be adapted to local conditions or other applications, such as the evaluation of vaccination campaigns. Most importantly, it facilitates the standardized collection of information without pen and paper, as well as straightforward sharing of collected data with the MSF headquarters or other aid organizations.

  3. Providers’ perspectives on inbound medical tourism in Central America and the Caribbean: factors driving and inhibiting sector development and their health equity implications

    PubMed Central

    Johnston, Rory; Crooks, Valorie A.; Cerón, Alejandro; Labonté, Ronald; Snyder, Jeremy; Núñez, Emanuel O.; Flores, Walter G.

    2016-01-01

    Background Many governments and health care providers worldwide are enthusiastic to develop medical tourism as a service export. Despite the popularity of this policy uptake, there is relatively little known about the specific local factors prospectively motivating and informing development of this sector. Objective To identify common social, economic, and health system factors shaping the development of medical tourism in three Central American and Caribbean countries and their health equity implications. Design In-depth, semi-structured interviews were conducted in Mexico, Guatemala, and Barbados with 150 health system stakeholders. Participants were recruited from private and public sectors working in various fields: trade and economic development, health services delivery, training and administration, and civil society. Transcribed interviews were coded using qualitative data management software, and thematic analysis was used to identify cross-cutting issues regarding the drivers and inhibitors of medical tourism development. Results Four common drivers of medical tourism development were identified: 1) unused capacity in existing private hospitals, 2) international portability of health insurance, vis-a-vis international hospital accreditation, 3) internationally trained physicians as both marketable assets and industry entrepreneurs, and 4) promotion of medical tourism by public export development corporations. Three common inhibitors for the development of the sector were also identified: 1) the high expense of market entry, 2) poor sector-wide planning, and 3) structural socio-economic issues such as insecurity or relatively high business costs and financial risks. Conclusion There are shared factors shaping the development of medical tourism in Central America and the Caribbean that help explain why it is being pursued by many hospitals and governments in the region. Development of the sector is primarily being driven by public investment promotion agencies and the private health sector seeking economic benefits with limited consideration and planning for the health equity concerns medical tourism raises. PMID:27876457

  4. Spatial heterogeneity in the carrying capacity of sika deer in Japan

    PubMed Central

    Iijima, Hayato; Ueno, Mayumi

    2016-01-01

    Abstract Carrying capacity is 1 driver of wildlife population dynamics. Although in previous studies carrying capacity was considered to be a fixed entity, it may differ among locations due to environmental variation. The factors underlying variability in carrying capacity, however, have rarely been examined. Here, we investigated spatial heterogeneity in the carrying capacity of Japanese sika deer ( Cervus nippon ) from 2005 to 2014 in Yamanashi Prefecture, central Japan (mesh with grid cells of 5.5×4.6 km) by state-space modeling. Both carrying capacity and density dependence differed greatly among cells. Estimated carrying capacities ranged from 1.34 to 98.4 deer/km 2 . According to estimated population dynamics, grid cells with larger proportions of artificial grassland and deciduous forest were subject to lower density dependence and higher carrying capacity. We conclude that population dynamics of ungulates may vary spatially through spatial variation in carrying capacity and that the density level for controlling ungulate abundance should be based on the current density level relative to the carrying capacity for each area. PMID:29692470

  5. Adaptation in Collaborative Governance Regimes

    NASA Astrophysics Data System (ADS)

    Emerson, Kirk; Gerlak, Andrea K.

    2014-10-01

    Adaptation and the adaptive capacity of human and environmental systems have been of central concern to natural and social science scholars, many of whom characterize and promote the need for collaborative cross-boundary systems that are seen as flexible and adaptive by definition. Researchers who study collaborative governance systems in the public administration, planning and policy literature have paid less attention to adaptive capacity specifically and institutional adaptation in general. This paper bridges the two literatures and finds four common dimensions of capacity, including structural arrangements, leadership, knowledge and learning, and resources. In this paper, we focus on institutional adaptation in the context of collaborative governance regimes and try to clarify and distinguish collaborative capacity from adaptive capacity and their contributions to adaptive action. We posit further that collaborative capacities generate associated adaptive capacities thereby enabling institutional adaptation within collaborative governance regimes. We develop these distinctions and linkages between collaborative and adaptive capacities with the help of an illustrative case study in watershed management within the National Estuary Program.

  6. Numerical computation of central crack growth in an active particle of electrodes influenced by multiple factors

    NASA Astrophysics Data System (ADS)

    Zhang, Yuwei; Guo, Zhansheng

    2018-03-01

    Mechanical degradation, especially fractures in active particles in an electrode, is a major reason why the capacity of lithium-ion batteries fades. This paper proposes a model that couples Li-ion diffusion, stress evolution, and damage mechanics to simulate the growth of central cracks in cathode particles (LiMn2O4) by an extended finite element method by considering the influence of multiple factors. The simulation shows that particles are likely to crack at a high discharge rate, when the particle radius is large, or when the initial central crack is longer. It also shows that the maximum principal tensile stress decreases and cracking becomes more difficult when the influence of crack surface diffusion is considered. The fracturing process occurs according to the following stages: no crack growth, stable crack growth, and unstable crack growth. Changing the charge/discharge strategy before unstable crack growth sets in is beneficial to prevent further capacity fading during electrochemical cycling.

  7. Enhanced clonal burst size corrects an otherwise defective memory response by CD8+ recent thymic emigrants

    PubMed Central

    Deets, Katherine A.; Berkley, Amy M.; Bergsbaken, Tessa; Fink, Pamela J.

    2016-01-01

    The youngest peripheral T cells (recent thymic emigrants or RTEs) are functionally distinct from naïve T cells that have completed post-thymic maturation. We now assess the RTE memory response, and find that RTEs produced less granzyme B than their mature counterparts during infection, but proliferated more and therefore generated equivalent target killing in vivo. After infection, RTE numbers contracted less dramatically than those of mature T cells, but RTEs were delayed in their transition to central memory, displaying impaired expression of CD62L, IL-2, Eomesodermin, and CXCR4, which resulted in impaired bone marrow localization. RTE-derived and mature memory cells expanded equivalently during rechallenge, indicating the robust proliferative capacity of RTEs was maintained independently of central memory phenotype. Thus, the diminished effector function and delayed central memory differentiation of RTE-derived memory cells are counterbalanced by their increased proliferative capacity, driving the efficacy of the RTE response to that of mature T cells. PMID:26873989

  8. Cutting Edge: Enhanced Clonal Burst Size Corrects an Otherwise Defective Memory Response by CD8+ Recent Thymic Emigrants.

    PubMed

    Deets, Katherine A; Berkley, Amy M; Bergsbaken, Tessa; Fink, Pamela J

    2016-03-15

    The youngest peripheral T cells (recent thymic emigrants [RTEs]) are functionally distinct from naive T cells that have completed postthymic maturation. We assessed the RTE memory response and found that RTEs produced less granzyme B than their mature counterparts during infection but proliferated more and, therefore, generated equivalent target killing in vivo. Postinfection, RTE numbers contracted less dramatically than those of mature T cells, but RTEs were delayed in their transition to central memory, displaying impaired expression of CD62L, IL-2, Eomesodermin, and CXCR4, which resulted in impaired bone marrow localization. RTE-derived and mature memory cells expanded equivalently during rechallenge, indicating that the robust proliferative capacity of RTEs was maintained independently of central memory phenotype. Thus, the diminished effector function and delayed central memory differentiation of RTE-derived memory cells are counterbalanced by their increased proliferative capacity, driving the efficacy of the RTE response to that of mature T cells. Copyright © 2016 by The American Association of Immunologists, Inc.

  9. Shared Decision-Making for Nursing Practice: An Integrative Review

    PubMed Central

    Truglio-Londrigan, Marie; Slyer, Jason T.

    2018-01-01

    Background: Shared decision-making has received national and international interest by providers, educators, researchers, and policy makers. The literature on shared decision-making is extensive, dealing with the individual components of shared decision-making rather than a comprehensive process. This view of shared decision-making leaves healthcare providers to wonder how to integrate shared decision-making into practice. Objective: To understand shared decision-making as a comprehensive process from the perspective of the patient and provider in all healthcare settings. Methods: An integrative review was conducted applying a systematic approach involving a literature search, data evaluation, and data analysis. The search included articles from PubMed, CINAHL, the Cochrane Central Register of Controlled Trials, and PsycINFO from 1970 through 2016. Articles included quantitative experimental and non-experimental designs, qualitative, and theoretical articles about shared decision-making between all healthcare providers and patients in all healthcare settings. Results: Fifty-two papers were included in this integrative review. Three categories emerged from the synthesis: (a) communication/ relationship building; (b) working towards a shared decision; and (c) action for shared decision-making. Each major theme contained sub-themes represented in the proposed visual representation for shared decision-making. Conclusion: A comprehensive understanding of shared decision-making between the nurse and the patient was identified. A visual representation offers a guide that depicts shared decision-making as a process taking place during a healthcare encounter with implications for the continuation of shared decisions over time offering patients an opportunity to return to the nurse for reconsiderations of past shared decisions. PMID:29456779

  10. Cloning and molecular characterization of the betaine aldehyde dehydrogenase involved in the biosynthesis of glycine betaine in white shrimp (Litopenaeus vannamei).

    PubMed

    Delgado-Gaytán, María F; Rosas-Rodríguez, Jesús A; Yepiz-Plascencia, Gloria; Figueroa-Soto, Ciria G; Valenzuela-Soto, Elisa M

    2017-10-01

    The enzyme betaine aldehyde dehydrogenase (BADH) catalyzes the irreversible oxidation of betaine aldehyde to glycine betaine (GB), a very efficient osmolyte accumulated during osmotic stress. In this study, we determined the nucleotide sequence of the cDNA for the BADH from the white shrimp Litopenaeus vannamei (LvBADH). The cDNA was 1882 bp long, with a complete open reading frame of 1524 bp, encoding 507 amino acids with a predicted molecular mass of 54.15 kDa and a pI of 5.4. The predicted LvBADH amino acid sequence shares a high degree of identity with marine invertebrate BADHs. Catalytic residues (C-298, E-264 and N-167) and the decapeptide VTLELGGKSP involved in nucleotide binding and highly conserved in BADHs were identified in the amino acid sequence. Phylogenetic analyses classified LvBADH in a clade that includes ALDH9 sequences from marine invertebrates. Molecular modeling of LvBADH revealed that the protein has amino acid residues and sequence motifs essential for the function of the ALDH9 family of enzymes. LvBADH modeling showed three potential monovalent cation binding sites, one site is located in an intra-subunit cavity; other in an inter-subunit cavity and a third in a central-cavity of the protein. The results show that LvBADH shares a high degree of identity with BADH sequences from marine invertebrates and enzymes that belong to the ALDH9 family. Our findings suggest that the LvBADH has molecular mechanisms of regulation similar to those of other BADHs belonging to the ALDH9 family, and that BADH might be playing a role in the osmoregulation capacity of L. vannamei. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Producing Cochrane systematic reviews-a qualitative study of current approaches and opportunities for innovation and improvement.

    PubMed

    Turner, Tari; Green, Sally; Tovey, David; McDonald, Steve; Soares-Weiser, Karla; Pestridge, Charlotte; Elliott, Julian

    2017-08-01

    Producing high-quality, relevant systematic reviews and keeping them up to date is challenging. Cochrane is a leading provider of systematic reviews in health. For Cochrane to continue to contribute to improvements in heath, Cochrane Reviews must be rigorous, reliable and up to date. We aimed to explore existing models of Cochrane Review production and emerging opportunities to improve the efficiency and sustainability of these processes. To inform discussions about how to best achieve this, we conducted 26 interviews and an online survey with 106 respondents. Respondents highlighted the importance and challenge of creating reliable, timely systematic reviews. They described the challenges and opportunities presented by current production models, and they shared what they are doing to improve review production. They particularly highlighted significant challenges with increasing complexity of review methods; difficulty keeping authors on board and on track; and the length of time required to complete the process. Strong themes emerged about the roles of authors and Review Groups, the central actors in the review production process. The results suggest that improvements to Cochrane's systematic review production models could come from improving clarity of roles and expectations, ensuring continuity and consistency of input, enabling active management of the review process, centralising some review production steps; breaking reviews into smaller "chunks", and improving approaches to building capacity of and sharing information between authors and Review Groups. Respondents noted the important role new technologies have to play in enabling these improvements. The findings of this study will inform the development of new Cochrane Review production models and may provide valuable data for other systematic review producers as they consider how best to produce rigorous, reliable, up-to-date reviews.

  12. Parents of children with neurogenic bowel dysfunction: their experiences of using transanal irrigation with their child.

    PubMed

    Sanders, C; Bray, L; Driver, C; Harris, V

    2014-11-01

    Neurogenic bowel dysfunction in children is a lifelong condition often resulting in the need for active bowel management programmes, such as transanal irrigation. Parents are central in the decision-making process to initiate and carry out treatments until such a time their child becomes independent. Minimal research has focussed on examining parents' experiences of undertaking transanal irrigation with their child. This study aimed to explore parents' experiences of learning about and using irrigation with their child and how parents motivated their children to become independent. Semi-structured telephone interviews were conducted with parents with experience of using transanal irrigation with their child. Interviews were undertaken by a parent researcher. Data were analysed using qualitative content analysis. Eighteen telephone interviews (16 mothers, 1 father and 1 carer) were conducted. Parents shared how they had negotiated getting started and using transanal irrigation with their child. They discussed a sense of success derived from their confidence in using and mastering irrigation, the process of making decisions to continue or stop using irrigation and how they motivated themselves and their child to continue with the irrigation regime. Challenges included minimizing their child's distress during the irrigation procedure and how they negotiated and moved towards their child becoming independent. Despite the emotional difficulty parents experienced as a result of the invasive nature of transanal irrigation most parents reported an improvement in their child's faecal continence which positively impacted on the child and family's lives. The child's physical ability and emotional readiness to develop independent irrigation skills in the future concerned some parents. The experiences shared by parents in this study has the capacity to inform transanal irrigation nursing and medical care. © 2013 John Wiley & Sons Ltd.

  13. 48 CFR 5152.208-9001 - Industrial preparedness planning.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... in paragraph (e) of this clause. As an LFPP for the listed items, the contractor will be solicited..., i.e. by assigning workload to a government-owned facility. (b) The Contractor agrees to: (i) Update... certifies that this capacity is not shared by any other mobilization production requirements. (e) This...

  14. The Role of Reading in Fostering Transcultural Competence

    ERIC Educational Resources Information Center

    Koda, Keiko

    2010-01-01

    This response was constructed based on the author's experience as a language program coordinator and her expertise in second language (L2) reading development. Because "transcultural competence," as defined in the MLA Report (2007), shares much of its underlying capacities with "reading ability," in principle, reading instruction could play a…

  15. Office of Environmental Information (OEI) Tribal Strategy: Partnership to Support Environmental Information and Decision-Making in Indian Country and Alaska Native Villages

    EPA Pesticide Factsheets

    This draft strategy provides a description of goals OEI seeks to accomplish to support tribal information and environmental decision-making. States objectives to facilitate and strengthen tribal capacity to collect, analyze and share data.

  16. Nurturing Interdisciplinary Competence in Academic Writing Classes: Two Taiwanese TESOL Professionals' Shared Journey

    ERIC Educational Resources Information Center

    Chen, Cheryl Wei-yu; Wang, Hung-chun

    2016-01-01

    This study delineates two Taiwanese TESOL teachers' efforts of combining English writing with entrepreneurship education to cultivate English majors' interdisciplinary competence in academic writing classes. An integrated business-and-writing approach was proposed to foster English majors' academic writing skills and entrepreneurial capacities. In…

  17. DOBIS and NOTIS: A Contrast in Design.

    ERIC Educational Resources Information Center

    Juergens, Bonnie; Blake, Ruth

    1987-01-01

    Compares and contrasts two systems designed for library automation applications--NOTIS, which was developed in the United States, and DOBIS, which was developed in Europe. The differences in the systems are discussed in terms of the availability or absence of machine readable bibliographic sharing capacities in the countries of origin. (CLB)

  18. Essentialism in the Absence of Language? Evidence from Rhesus Monkeys ("Macaca mulatta")

    ERIC Educational Resources Information Center

    Phillips, Webb; Shankar, Maya; Santos, Laurie R.

    2010-01-01

    We explored whether rhesus monkeys (Macaca mulatta) share one important feature of human essentialist reasoning: the capacity to track category membership across radical featural transformations. Specifically, we examined whether monkeys--like children (Keil, 1989)--expect a transformed object to have the internal properties of its original…

  19. District-Charter Collaboration Grant Implementation: Findings from Teacher and Principal Surveys. Summary Brief

    ERIC Educational Resources Information Center

    Richman, Scott; Burnett, Alyson; Dillon, Erin; Goble, Lisbeth; McCullough, Moira; Tuttle, Christina Clark

    2016-01-01

    In November 2012, the Bill & Melinda Gates Foundation invested in seven innovative district-charter partnerships with "the potential capacity and commitment to accelerate student college ready rates through deep collaboration and sharing of best practices" (District-Charter Collaboration Grant Request for Proposal). These…

  20. District-Charter Collaboration Grant Implementation: Final Findings from Interviews and Site Visits. Interim Report

    ERIC Educational Resources Information Center

    McCullough, Moira; Keating, Betsy; Heinkel, Luke

    2016-01-01

    In November 2012, the Bill & Melinda Gates Foundation invested in seven innovative district-charter partnerships with "the potential capacity and commitment to accelerate student college ready rates through deep collaboration and sharing of best practices" (District-Charter Collaboration Grant Request for Proposal). These…

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