Sample records for central difference approximation

  1. Rapidity dependence of antiproton-to-proton ratios in Au+Au collisions at square root of (sNN) = 130 GeV.

    PubMed

    Bearden, I G; Beavis, D; Besliu, C; Blyakhman, Y; Brzychczyk, J; Budick, B; Bøggild, H; Chasman, C; Christensen, C H; Christiansen, P; Cibor, J; Debbe, R; Gaardhøje, J J; Grotowski, K; Hagel, K; Hansen, O; Holm, A; Holme, A K; Ito, H; Jakobsen, E; Jipa, A; Jørdre, J I; Jundt, F; Jørgensen, C E; Keutgen, T; Kim, E J; Kozik, T; Larsen, T M; Lee, J H; Lee, Y K; Løvhøiden, G L; Majka, Z; Makeev, A; McBreen, B; Murray, M; Natowitz, J; Nielsen, B S; Olchanski, K; Olness, J; Ouerdane, D; Planeta, R; Rami, F; Röhrich, D; Samset, B H; Sanders, S J; Sheetz, R A; Sosin, Z; Staszel, P; Thorsteinsen, T F; Tveter, T S; Videbaek, F; Wada, R; Wieloch, A; Zgura, I S

    2001-09-10

    Measurements, with the BRAHMS detector, of the antiproton-to-proton ratio at midrapidities and forward rapidities, are presented for Au+Au reactions at square root of [s(NN)] = 130 GeV, and for three different collision centralities. For collisions in the 0%-40% centrality range, we find N(&pmacr;)/N(p) = 0.64+/-0.04((stat))+/-0.06((syst)) at y approximately 0, 0.66+/-0.03+/-0.06 at y approximately 0.7, and 0.41+/-0.04+/-0.06 at y approximately 2. The ratios are found to be nearly independent of collision centrality and transverse momentum. The antiproton and proton rapidity densities vary differently with rapidity, and indicate a significant degree of collision transparency, although a net-baryon free midrapidity plateau (Bjorken limit) is not yet reached.

  2. Automated facial recognition and candidate list rank change of computer generated facial approximations generated with multiple eye orb positions.

    PubMed

    Parks, Connie L; Monson, Keith L

    2016-09-01

    Expanding on research previously reported by the authors, this study further examines the recognizability of ReFace facial approximations generated with the following eye orb positions: (i) centrally within the bony eye socket, (ii) 1.0mm superior and 2.0mm lateral relative to center, and (iii) 1.0mm superior and 2.5mm lateral relative to center. Overall, 81% of the test subjects' approximation ranks improved with the use of either of the two supero-lateral eye orbs. Highly significant performance differences (p<0.01) were observed between the approximations with centrally positioned eye orbs (i) and approximations with the eye orbs placed in the supero-laterally positions (ii and iii). Noteworthy was the observation that in all cases when the best rank for an approximation was obtained with the eye orbs in position (iii), the second best rank was achieved with the eye orbs in position (ii). A similar pattern was also observed when the best rank was obtained with the eye orbs in position (ii), with 60% of the second best ranks observed in position (iii). It is argued, therefore, that an approximation constructed with the eye orbs placed in either of the two supero-lateral positions may be more effective and operationally informative than centrally positioned orbs. Copyright © 2016. Published by Elsevier Ireland Ltd.

  3. An algorithm for solving the perturbed gas dynamic equations

    NASA Technical Reports Server (NTRS)

    Davis, Sanford

    1993-01-01

    The present application of a compact, higher-order central-difference approximation to the linearized Euler equations illustrates the multimodal character of these equations by means of computations for acoustic, vortical, and entropy waves. Such dissipationless central-difference methods are shown to propagate waves exhibiting excellent phase and amplitude resolution on the basis of relatively large time-steps; they can be applied to wave problems governed by systems of first-order partial differential equations.

  4. Effects of Different Treatments of Pasture Restoration on Soil Trace Gas Emissions in the Cerrados of Central Brazil

    EPA Science Inventory

    Planted pastures ( mainly Brachiaria spp) are the most extensive land use in the cerrado (savannas of central Brazil) with an area of approximately 50 x 10(6) ha. The objective of the study was to assess the effects of pasture restoration on the N dynamics ( net N mineralization/...

  5. Black-Scholes finite difference modeling in forecasting of call warrant prices in Bursa Malaysia

    NASA Astrophysics Data System (ADS)

    Mansor, Nur Jariah; Jaffar, Maheran Mohd

    2014-07-01

    Call warrant is a type of structured warrant in Bursa Malaysia. It gives the holder the right to buy the underlying share at a specified price within a limited period of time. The issuer of the structured warrants usually uses European style to exercise the call warrant on the maturity date. Warrant is very similar to an option. Usually, practitioners of the financial field use Black-Scholes model to value the option. The Black-Scholes equation is hard to solve analytically. Therefore the finite difference approach is applied to approximate the value of the call warrant prices. The central in time and central in space scheme is produced to approximate the value of the call warrant prices. It allows the warrant holder to forecast the value of the call warrant prices before the expiry date.

  6. Helicopter electromagnetic and magnetic geophysical survey data, Hunton anticline, south-central Oklahoma

    USGS Publications Warehouse

    Smith, Bruce D.; Smith, David V.; Deszcz-Pan, Maryla; Blome, Charles D.; Hill, Patricia

    2011-01-01

    This report is a digital data release for multiple geophysical surveys conducted in the Hunton anticline area of south-central Oklahoma. The helicopter electromagnetic and magnetic surveys were flown on March 16–17, 2007, in four areas of the Hunton anticline in south-central Oklahoma. The objective of this project is to improve the understanding of the geohydrologic framework of the Arbuckle-Simpson aquifer. The electromagnetic sensor for the helicopter electromagnetic survey consisted of six different transmitter-receiver orientations that measured the earth's electrical response at six distinct frequencies from approximately 500 Hertz to approximately 115,000 Hertz. The electromagnetic measurements were converted to electrical resistivity values, which were gridded and plotted on georeferenced maps. The map from each frequency represents a different depth of investigation for each area. The range of subsurface investigation is comparable to the depth of shallow groundwater. The four areas selected for the helicopter electromagnetic study, blocks A–D, have different geologic and hydrologic settings. Geophysical and hydrologic information from U.S. Geological Survey studies are being used by modelers and resource managers to develop groundwater resource plans for the Arbuckle-Simpson aquifer.

  7. Numerical solution of nonlinear partial differential equations of mixed type. [finite difference approximation

    NASA Technical Reports Server (NTRS)

    Jameson, A.

    1976-01-01

    A review is presented of some recently developed numerical methods for the solution of nonlinear equations of mixed type. The methods considered use finite difference approximations to the differential equation. Central difference formulas are employed in the subsonic zone and upwind difference formulas are used in the supersonic zone. The relaxation method for the small disturbance equation is discussed and a description is given of difference schemes for the potential flow equation in quasi-linear form. Attention is also given to difference schemes for the potential flow equation in conservation form, the analysis of relaxation schemes by the time dependent analogy, the accelerated iterative method, and three-dimensional calculations.

  8. Improving the accuracy of central difference schemes

    NASA Technical Reports Server (NTRS)

    Turkel, Eli

    1988-01-01

    General difference approximations to the fluid dynamic equations require an artificial viscosity in order to converge to a steady state. This artificial viscosity serves two purposes. One is to suppress high frequency noise which is not damped by the central differences. The second purpose is to introduce an entropy-like condition so that shocks can be captured. These viscosities need a coefficient to measure the amount of viscosity to be added. In the standard scheme, a scalar coefficient is used based on the spectral radius of the Jacobian of the convective flux. However, this can add too much viscosity to the slower waves. Hence, it is suggested that a matrix viscosity be used. This gives an appropriate viscosity for each wave component. With this matrix valued coefficient, the central difference scheme becomes closer to upwind biased methods.

  9. Differing Gender Preferences for Educational Media among Thai Students Studying English at University

    ERIC Educational Resources Information Center

    Grubbs, Samuel Jacob

    2012-01-01

    There have been many reports indicating that there are differences between male and female students in various issues in education. This research examined the preferences for various forms of educational media by freshmen students studying English in Thailand. Approximately 3000 students at seven university campuses in central Thailand were…

  10. Revision of the documentation for a model for calculating effects of liquid waste disposal in deep saline aquifers

    USGS Publications Warehouse

    INTERA Environmental Consultants, Inc.

    1979-01-01

    The major limitation of the model arises using second-order correct (central-difference) finite-difference approximation in space. To avoid numerical oscillations in the solution, the user must restrict grid block and time step sizes depending upon the magnitude of the dispersivity.

  11. A seismic survey of the Manson disturbed area

    NASA Technical Reports Server (NTRS)

    Sendlein, L. V. A.; Smith, T. A.

    1971-01-01

    The region in north-central Iowa referred to as the Manson disturbed area was investigated with the seismic refraction method and the bedrock configuration mapped. The area is approximately 30 km in diameter and is not detectable from the surface topography; however, water wells that penetrate the bedrock indicate that the bedrock is composed of disturbed Cretaceous sediments with a central region approximately 6 km in diameter composed of Precambrian crystalline rock. Seismic velocity differences between the overlying glacial till and the Cretaceous sediments were so small that a statistical program was developed to analyze the data. The program developed utilizes existing 2 segment regression analyses and extends the method to fit 3 or more regression lines to seismic data.

  12. Optimal Keno Strategies and the Central Limit Theorem

    ERIC Educational Resources Information Center

    Johnson, Roger W.

    2006-01-01

    For the casino game Keno we determine optimal playing strategies. To decide such optimal strategies, both exact (hypergeometric) and approximate probability calculations are used. The approximate calculations are obtained via the Central Limit Theorem and simulation, and an important lesson about the application of the Central Limit Theorem is…

  13. CAD/CAM transtibial prosthetic sockets from central fabrication facilities: How accurate are they?

    PubMed Central

    Sanders, Joan E.; Rogers, Ellen L.; Sorenson, Elizabeth A.; Lee, Gregory S.; Abrahamson, Daniel C.

    2014-01-01

    This research compares transtibial prosthetic sockets made by central fabrication facilities with their corresponding American Academy of Orthotists and Prosthetists (AAOP) electronic shape files and assesses the central fabrication process. We ordered three different socket shapes from each of 10 manufacturers. Then we digitized the sockets using a very accurate custom mechanical digitizer. Results showed that quality varied considerably among the different manufacturers. Four of the companies consistently made sockets within +/−1.1% volume (approximately 1 sock ply) of the AAOP electronic shape file, while six other companies did not. Six of the companies showed consistent undersizing or oversizing in their sockets, which suggests a consistent calibration or manufacturing error. Other companies showed inconsistent sizing or shape distortion, a difficult problem that represents a most challenging limitation for central fabrication facilities. PMID:18247236

  14. Blue lobes in the Hydra A cluster central galaxy

    NASA Technical Reports Server (NTRS)

    Mcnamara, Brian R.

    1995-01-01

    We present new U- and I-band images of the centrally dominant galaxy in the Hydra A cluster, obtained with the 2.5 m Isaac Newton Telescope at La Palma. The galaxy is centered in a poor, X-ray-luminous cluster whose gaseous intracluster medium is apparently cooling at a rate of m-dot(sub CF) approximately 3000 solar masses/yr. The galaxy's structure is that of a normal giant elliptical galaxy, apart from the central approximately 8 x 6 arcsec (approximately 12 x 9 kpc) region which contains an unusually blue, lobelike structure that is spatially coincident with a luminous emission-line nebula in rotation about the nucleus. Based on near spatial coincidence of the central continuum structure and the emission-line nebula, we suggest that the blue continuum is due to a warm stellar population in a central disk. In order to isolate and study the structure of the disk, we have subtracted a smooth galactic background model from the U-band image. The disk's surface brightness profiles along its major and minor axes decline roughly exponentially with radius. The disk's axial ratio is consistent with a nearly edge-on thick disk or a thin disk that is inclined with respect to the line of sight. The bluest regions, located a few arcsec on either side of the nucleus (giving the lobelike appearance), may be due to locally enhanced star formation or a seeing-blurred ring of young stars embedded in the disk observed nearly edge-on. If star-formation is occurring with the local initial mass function, the central color, surface brightness, and dynamical mass would be consistent with models for star formation at a rate of less than and approximately 1 solar masses/yr which has persisted for the past approximately 10(exp 9) yr, a short burst (10(exp 7) yr) of star formation at a rate of approximately 30 solar masses/yr which occurred less than and approximately 10(exp 8) yr ago, or an instantaneous burst of star formation which occurred approximately 5 x 10(exp 7) yr ago. While the young population contributes approximately 30%-40% of the central U-band luminosity, its mass would be less than and approximately 1% to less than and approximately 10% (10(exp 8) solar masses - 2 x 10(exp 9) solar masses of the galaxy's central dynamical mass. We consider a number of possible origins for the disk material.

  15. Normalization and Implementation of Three Gravitational Acceleration Models

    NASA Technical Reports Server (NTRS)

    Eckman, Randy A.; Brown, Aaron J.; Adamo, Daniel R.; Gottlieb, Robert G.

    2016-01-01

    Unlike the uniform density spherical shell approximations of Newton, the consequence of spaceflight in the real universe is that gravitational fields are sensitive to the asphericity of their generating central bodies. The gravitational potential of an aspherical central body is typically resolved using spherical harmonic approximations. However, attempting to directly calculate the spherical harmonic approximations results in at least two singularities that must be removed to generalize the method and solve for any possible orbit, including polar orbits. Samuel Pines, Bill Lear, and Robert Gottlieb developed three unique algorithms to eliminate these singularities. This paper documents the methodical normalization of two of the three known formulations for singularity-free gravitational acceleration (namely, the Lear and Gottlieb algorithms) and formulates a general method for defining normalization parameters used to generate normalized Legendre polynomials and Associated Legendre Functions (ALFs) for any algorithm. A treatment of the conventional formulation of the gravitational potential and acceleration is also provided, in addition to a brief overview of the philosophical differences between the three known singularity-free algorithms.

  16. On the stability analysis of approximate factorization methods for 3D Euler and Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Demuren, A. O.; Ibraheem, S. O.

    1993-01-01

    The convergence characteristics of various approximate factorizations for the 3D Euler and Navier-Stokes equations are examined using the von-Neumann stability analysis method. Three upwind-difference based factorizations and several central-difference based factorizations are considered for the Euler equations. In the upwind factorizations both the flux-vector splitting methods of Steger and Warming and van Leer are considered. Analysis of the Navier-Stokes equations is performed only on the Beam and Warming central-difference scheme. The range of CFL numbers over which each factorization is stable is presented for one-, two-, and three-dimensional flow. Also presented for each factorization is the CFL number at which the maximum eigenvalue is minimized, for all Fourier components, as well as for the high frequency range only. The latter is useful for predicting the effectiveness of multigrid procedures with these schemes as smoothers. Further, local mode analysis is performed to test the suitability of using a uniform flow field in the stability analysis. Some inconsistencies in the results from previous analyses are resolved.

  17. Effects of the Temporal Variability of Evapotranspiration on Hydrologic Simulation in Central Florida

    USGS Publications Warehouse

    O'Reilly, Andrew M.

    2007-01-01

    The transient response of a hydrologic system can be of concern to water-resource managers, because it is often extreme relatively short-lived events, such as floods or droughts, that profoundly influence the management of the resource. The water available to a hydrologic system for stream flow and aquifer recharge is determined by the difference of precipitation and evapotranspiration (ET). As such, temporal variations in precipitation and ET determine the degree of influence each has on the transient response of the hydrologic system. Meteorological, ET, and hydrologic data collected from 1993 to 2003 and spanning 1- to 3 2/3 -year periods were used to develop a hydrologic model for each of five sites in central Florida. The sensitivities of simulated water levels and flows to simple approximations of ET were quantified and the adequacy of each ET approximation was assessed. ET was approximated by computing potential ET, using the Hargreaves and Priestley-Taylor equations, and applying vegetation coefficients to adjust the potential ET values to actual ET. The Hargreaves and Priestley-Taylor ET approximations were used in the calibrated hydrologic models while leaving all other model characteristics and parameter values unchanged. Two primary factors that influence how the temporal variability of ET affects hydrologic simulation in central Florida were identified: (1) stochastic character of precipitation and ET and (2) the ability of the local hydrologic system to attenuate variability in input stresses. Differences in the stochastic character of precipitation and ET, both the central location and spread of the data, result in substantial influence of precipitation on the quantity and timing of water available to the hydrologic system and a relatively small influence of ET. The temporal variability of ET was considerably less than that of precipitation at each site over a wide range of time scales (from daily to annual). However, when precipitation and ET are of similar magnitude, small errors in ET can produce relatively large errors in available water, and accurate estimates of actual ET are more important. Local hydrologic conditions can also be an important factor influencing the hydrologic response to ET variability. Various points along a flow path in a hydrologic system respond differently to temporal variations in ET. For example, soil moisture contents in the root zone are sensitive to daily variations in ET, whereas spring flow responds to only longer term variations in ET. Both the Hargreaves and Priestley-Taylor equations for potential ET, when applied with an annually invariant monthly vegetation coefficient derived from comparison of measured ET with computed potential ET values, can be used with a hydrologic model to produce reasonable predictions of water levels and flows. Baseline-adjusted modified coefficients of efficiency for simulated water levels ranged from 0.0, indicating that water levels were simulated equally as well with approximated ET as with actual ET values, to -0.6, indicating that water levels were simulated better with actual ET values. Simulations using the Hargreaves approximation consistently yielded larger absolute and relative errors than the Priestley-Taylor approximation. However, the differences between the Hargreaves and Priestley-Taylor simulations generally were much smaller than differences between these simulations and the simulations using actual ET. This suggests that the simpler Hargreaves equation may be an adequate substitute for the more complex Priestley-Taylor equation, depending on the level of accuracy required to satisfy the particular modeling objectives.

  18. Spatiotemporal processing of linear acceleration: primary afferent and central vestibular neuron responses

    NASA Technical Reports Server (NTRS)

    Angelaki, D. E.; Dickman, J. D.

    2000-01-01

    Spatiotemporal convergence and two-dimensional (2-D) neural tuning have been proposed as a major neural mechanism in the signal processing of linear acceleration. To examine this hypothesis, we studied the firing properties of primary otolith afferents and central otolith neurons that respond exclusively to horizontal linear accelerations of the head (0.16-10 Hz) in alert rhesus monkeys. Unlike primary afferents, the majority of central otolith neurons exhibited 2-D spatial tuning to linear acceleration. As a result, central otolith dynamics vary as a function of movement direction. During movement along the maximum sensitivity direction, the dynamics of all central otolith neurons differed significantly from those observed for the primary afferent population. Specifically at low frequencies (

  19. Mycobacterium tuberculosis infection in grazing cattle in central Ethiopia.

    PubMed

    Ameni, Gobena; Vordermeier, Martin; Firdessa, Rebuma; Aseffa, Abraham; Hewinson, Glyn; Gordon, Stephen V; Berg, Stefan

    2011-06-01

    A preliminary study to characterise mycobacteria infecting tuberculous cattle from two different management systems in central Ethiopia was carried out. Approximately 27% of isolates from grazing cattle were Mycobacterium tuberculosis, while cattle in a more intensive-production system were exclusively infected with M. bovis. The practice of local farmers discharging chewed tobacco directly into the mouths of pastured cattle was identified as a potential route of human-to-cattle transmission of M. tuberculosis. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Central masking with bilateral cochlear implants

    PubMed Central

    Lin, Payton; Lu, Thomas; Zeng, Fan-Gang

    2013-01-01

    Across bilateral cochlear implants, contralateral threshold shift has been investigated as a function of electrode difference between the masking and probe electrodes. For contralateral electric masking, maximum threshold elevations occurred when the position of the masker and probe electrode was approximately place-matched across ears. The amount of masking diminished with increasing masker-probe electrode separation. Place-dependent masking occurred in both sequentially implanted ears, and was not affected by the masker intensity or the time delay from the masker onset. When compared to previous contralateral masking results in normal hearing, the similarities between place-dependent central masking patterns suggest comparable mechanisms of overlapping excitation in the central auditory nervous system. PMID:23363113

  1. The fusimotor and reafferent origin of the sense of force and weight

    PubMed Central

    Luu, Billy L; Day, Brian L; Cole, Jonathan D; Fitzpatrick, Richard C

    2011-01-01

    Abstract Signals associated with the command the brain sends to muscles are thought to create the sensation of heaviness when we lift an object. Thus, as a muscle is weakened by fatigue or partial paralysis (neuromuscular blockade), the increase in the motor command needed to lift a weight is thought to explain the increasing subjective heaviness of the lifted object. With different fatiguing contractions we approximately halved the force output of the thumb flexor muscles, which were then used to lift an object. For two deafferented subjects the perceived heaviness of the lifted object approximately doubled, in keeping with the central-signal theory. However, for normal subjects this resulted in objects feeling the same or lighter, inconsistent with the central-signal theory but consistent with the expected effects of the conditioning contractions on the sensitivity of peripheral receptors. In separate experiments we subjected the forearm muscles to complete paralysis with a non-depolarising neuromuscular blocking agent and then allowed them to recover to approximately half-force output. This also resulted in objects feeling lighter when lifted by the semi-paralysed thumb, even though the motor command to the motoneurons must have been greater. This is readily explained by reduced lift-related reafference caused by the prolonged paralysis of muscle spindle intrafusal fibres. We conclude that peripheral signals, including a major contribution from muscle spindles, normally give rise to the sense of exerted force. In concept, however, reafference from peripheral receptors may also be considered a centrally generated signal that traverses efferent and then afferent pathways to feed perceptual centres rather than one confined entirely to the central nervous system. These results therefore challenge the distinction between central- and peripheral-based perception, and the concept that muscle spindles provide only information about limb position and movement. PMID:21521756

  2. Identified baryon and meson distributions at large transverse momenta from Au + Au collisions at square root sNN=200 GeV.

    PubMed

    Abelev, B I; Aggarwal, M M; Ahammed, Z; Anderson, B D; Anderson, M; Arkhipkin, D; Averichev, G S; Bai, Y; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Bekele, S; Belaga, V V; Bellingeri-Laurikainen, A; Bellwied, R; Benedosso, F; Bhardwaj, S; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Blyth, S-L; Bonner, B E; Botje, M; Bouchet, J; Brandin, A V; Bravar, A; Burton, T P; Bystersky, M; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Castillo, J; Catu, O; Cebra, D; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Coffin, J P; Cormier, T M; Cosentino, M R; Cramer, J G; Crawford, H J; Das, D; Das, S; Dash, S; Daugherity, M; de Moura, M M; Dedovich, T G; Dephillips, M; Derevschikov, A A; Didenko, L; Dietel, T; Djawotho, P; Dogra, S M; Dong, W J; Dong, X; Draper, J E; Du, F; Dunin, V B; Dunlop, J C; Dutta Mazumdar, M R; Eckardt, V; Edwards, W R; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Fatemi, R; Fedorisin, J; Filip, P; Finch, E; Fine, V; Fisyak, Y; Fu, J; Gagliardi, C A; Gaillard, L; Ganti, M S; Ghazikhanian, V; Ghosh, P; Gonzalez, J E; Gorbunov, Y G; Gos, H; Grebenyuk, O; Grosnick, D; Guertin, S M; Guimaraes, K S F F; Gupta, N; Gutierrez, T D; Haag, B; Hallman, T J; Hamed, A; Harris, J W; He, W; Heinz, M; Henry, T W; Hepplemann, S; Hippolyte, B; Hirsch, A; Hjort, E; Hoffman, A M; Hoffmann, G W; Horner, M J; Huang, H Z; Huang, S L; Hughes, E W; Humanic, T J; Igo, G; Jacobs, P; Jacobs, W W; Jakl, P; Jia, F; Jiang, H; Jones, P G; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kaplan, M; Keane, D; Kechechyan, A; Khodyrev, V Yu; Kim, B C; Kiryluk, J; Kisiel, A; Kislov, E M; Klein, S R; Kocoloski, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kouchpil, V; Kowalik, K L; Kramer, M; Kravtsov, P; Kravtsov, V I; Krueger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; Lapointe, S; Laue, F; Lauret, J; Lebedev, A; Lednicky, R; Lee, C-H; Lehocka, S; Levine, M J; Li, C; Li, Q; Li, Y; Lin, G; Lin, X; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, H; Liu, J; Liu, L; Liu, Z; Ljubicic, T; Llope, W J; Long, H; Longacre, R S; Love, W A; Lu, Y; Ludlam, T; Lynn, D; Ma, G L; Ma, J G; Ma, Y G; Magestro, D; Mahapatra, D P; Majka, R; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Martin, L; Matis, H S; Matulenko, Yu A; McClain, C J; McShane, T S; Melnick, Yu; Meschanin, A; Millane, J; Miller, M L; Minaev, N G; Mioduszewski, S; Mironov, C; Mischke, A; Mishra, D K; Mitchell, J; Mohanty, B; Molnar, L; Moore, C F; Morozov, D A; Munhoz, M G; Nandi, B K; Nattrass, C; Nayak, T K; Nelson, J M; Nepali, N S; Netrakanti, P K; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Pachr, M; Pal, S K; Panebratsev, Y; Panitkin, S Y; Pavlinov, A I; Pawlak, T; Peitzmann, T; Perevoztchikov, V; Perkins, C; Peryt, W; Phatak, S C; Picha, R; Planinic, M; Pluta, J; Poljak, N; Porile, N; Porter, J; Poskanzer, A M; Potekhin, M; Potrebenikova, E; Potukuchi, B V K S; Prindle, D; Pruneau, C; Putschke, J; Rakness, G; Raniwala, R; Raniwala, S; Ray, R L; Razin, S V; Reinnarth, J; Relyea, D; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Rose, A; Roy, C; Ruan, L; Russcher, M J; Sahoo, R; Sakuma, T; Salur, S; Sandweiss, J; Sarsour, M; Sazhin, P S; Schambach, J; Scharenberg, R P; Schmitz, N; Seger, J; Selyuzhenkov, I; Seyboth, P; Shabetai, A; Shahaliev, E; Shao, M; Sharma, M; Shen, W Q; Shimanskiy, S S; Sichtermann, E P; Simon, F; Singaraju, R N; Smirnov, N; Snellings, R; Sood, G; Sorensen, P; Sowinski, J; Speltz, J; Spinka, H M; Srivastava, B; Stadnik, A; Stanislaus, T D S; Stock, R; Stolpovsky, A; Strikhanov, M; Stringfellow, B; Suaide, A A P; Subba, N L; Sugarbaker, E; Sumbera, M; Sun, Z; Surrow, B; Swanger, M; Symons, T J M; Szanto de Toledo, A; Tai, A; Takahashi, J; Tang, A H; Tarnowsky, T; Thein, D; Thomas, J H; Timmins, A R; Timoshenko, S; Tokarev, M; Trainor, T A; Trentalange, S; Tribble, R E; Tsai, O D; Ulery, J; Ullrich, T; Underwood, D G; Van Buren, G; van der Kolk, N; van Leeuwen, M; Vander Molen, A M; Varma, R; Vasilevski, I M; Vasiliev, A N; Vernet, R; Vigdor, S E; Viyogi, Y P; Vokal, S; Voloshin, S A; Waggoner, W T; Wang, F; Wang, G; Wang, J S; Wang, X L; Wang, Y; Watson, J W; Webb, J C; Westfall, G D; Wetzler, A; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wood, J; Wu, J; Xu, N; Xu, Q H; Xu, Z; Yepes, P; Yoo, I-K; Yurevich, V I; Zhan, W; Zhang, H; Zhang, W M; Zhang, Y; Zhang, Z P; Zhao, Y; Zhong, C; Zoulkarneev, R; Zoulkarneeva, Y; Zubarev, A N; Zuo, J X

    2006-10-13

    Transverse momentum spectra of pi+/-, p, and p up to 12 GeV/c at midrapidity in centrality selected Au + Au collisions at square root sNN=200 GeV are presented. In central Au + Au collisions, both pi +/- and p(p) show significant suppression with respect to binary scaling at pT approximately >4 GeV/c. Protons and antiprotons are less suppressed than pi+/-, in the range 1.5 approximately < pT approximately < 6 GeV/c. The pi-/pi+ and p/p ratios show at most a weak pT dependence and no significant centrality dependence. The p/pi ratios in central Au + Au collisions approach the values in p + p and d + Au collisions at pT approximately >5 GeV/c. The results at high pT indicate that the partonic sources of pi+/-, p, and p have similar energy loss when traversing the nuclear medium.

  3. Normalization of Gravitational Acceleration Models

    NASA Technical Reports Server (NTRS)

    Eckman, Randy A.; Brown, Aaron J.; Adamo, Daniel R.

    2011-01-01

    Unlike the uniform density spherical shell approximations of Newton, the con- sequence of spaceflight in the real universe is that gravitational fields are sensitive to the nonsphericity of their generating central bodies. The gravitational potential of a nonspherical central body is typically resolved using spherical harmonic approximations. However, attempting to directly calculate the spherical harmonic approximations results in at least two singularities which must be removed in order to generalize the method and solve for any possible orbit, including polar orbits. Three unique algorithms have been developed to eliminate these singularities by Samuel Pines [1], Bill Lear [2], and Robert Gottlieb [3]. This paper documents the methodical normalization of two1 of the three known formulations for singularity-free gravitational acceleration (namely, the Lear [2] and Gottlieb [3] algorithms) and formulates a general method for defining normalization parameters used to generate normalized Legendre Polynomials and ALFs for any algorithm. A treatment of the conventional formulation of the gravitational potential and acceleration is also provided, in addition to a brief overview of the philosophical differences between the three known singularity-free algorithms.

  4. Anaglyph Image of the Mountain-Central Complex in Vesta South Polar Region

    NASA Image and Video Library

    2011-10-11

    The broad morphology of asteroid Vesta mountain/central complex is clear in this image from NASA Dawn spacecraft; it is a roughly circular topographic mound, which is approximately 200km in diameter and has approximately 20km of relief from its base.

  5. The Formation and Erosion History of Mt. Sharp

    NASA Technical Reports Server (NTRS)

    Allen, Carlton C.; Dapremont, Angela M.

    2014-01-01

    The Curiosity rover is exploring 155 km diameter Gale crater and Mt. Sharp, Gale's 5 km high central mound (Fig. 1). This study addresses the formation and erosion history of Mt. Sharp. Gale lies on the topographic dichotomy between the southern highlands and the northern plains - a drop of over 2 km [1,2]. Altitude differences between the north and south rim reflect this regional slope, as do altitude differences between the deep annulus north of Mt. Sharp and the southern crater floor. Orbiter and rover images demonstrate that most exposed areas on Mt. Sharp consist of thin, sub-parallel units interpreted as sedimentary layers [3]. Gale is typical of the 50 large martian craters that have been totally or partially filled with such layers [4,5]. In many craters these sediments have been deeply eroded. Central Peak and Peak Ring: The highest point on Mt. Sharp, near the crater's center, is interpreted as a central peak [6]. The peak has a massive lower portion and a thin, smooth capping deposit (Fig. 2). Gale's size is transitional between martian craters with single central peaks and craters with peak rings approximately half the crater's diameter [2,6]. The boundaries of Mt. Sharp, as well as an arc of hills to the southeast of the mountain, closely match a circle approximately 80 km in diameter (Fig. 3). This morphology suggests that the Gale impact may have formed both a central peak and a partial peak ring, which is covered by the sediments of Mt. Sharp in the north and possibly exposed in the arc of eroded hills in the southeast quadrant (Figs. 3,4).

  6. High order filtering methods for approximating hyperbolic systems of conservation laws

    NASA Technical Reports Server (NTRS)

    Lafon, F.; Osher, S.

    1991-01-01

    The essentially nonoscillatory (ENO) schemes, while potentially useful in the computation of discontinuous solutions of hyperbolic conservation-law systems, are computationally costly relative to simple central-difference methods. A filtering technique is presented which employs central differencing of arbitrarily high-order accuracy except where a local test detects the presence of spurious oscillations and calls upon the full ENO apparatus to remove them. A factor-of-three speedup is thus obtained over the full-ENO method for a wide range of problems, with high-order accuracy in regions of smooth flow.

  7. The Interactive Association of General Obesity and Central Obesity with Prevalent Hypertension in Rural Lanzhou, China

    PubMed Central

    Wang, Yuhong; Wan, Liping; Wang, Zengwu; Wang, Xin; Di, Zhaoxin; Liu, Xiaoyu

    2016-01-01

    Objective To evaluate the interactive association between obesity with different anthropometry indices and prevalence of hypertension in rural Lanzhou. Methods A cross-sectional survey was conducted in rural Lanzhou from April to July in 2013. The available information of 1275 rural residents aged more than 35 years was collected with a unified questionnaire and their blood pressure and anthropometry indices were measured in the field. The male-to-female ratio was 1:1.1. A generalized estimate equation (GEE) linear model was used to determine the association between obesity with different indexes and hypertension. Results There was a moderate prevalence of general obesity (~11%) and very high prevalence of central obesity (53.2~67%) among the adults of rural Lanzhou. The prevalence of hypertension approximated 28%. GEE linear models showed that obesity with any one of anthropometry indices was associated significantly with the increased prevalence of hypertension among both males and females. In females, general obesity increased the prevalence of hypertension by 37% (0.37, 95%CI: 0.27,0.47) but in males by 23% (0.23, 95%CI: 0.12,0.35). The hypertensive effect of all central obesity was much lower than that of general obesity but approximately comparable to that of overweight. In addition, the interactions of the classified body mass index (BMI) and central obesity showed that when general obesity or overweight coexisted with any one of central obesity, the prevalence of hypertension was increased significantly, and this effect was a little higher than the corresponding main effect of general obesity or overweight in females but was much higher in males. In addition, general obesity or overweight which did not coexist with central obesity was not significantly associated with the increased prevalence of hypertension, nor were the other situations of central obesity in the normal weight or underweight except for the situation of central obesity with waist-to-hip ratio in the males of normal weight or underweight. Conclusion In rural Lanzhou, higher BMI had larger associations with the increased prevalence of hypertension than central obesity indices. Only when general obesity or overweight coexisted with central obesity, the prevalence of hypertension was significantly increased. So, central obesity indices should be used jointly with BMI in evaluating the risk of hypertension. PMID:27732655

  8. An Examination of the Role of Listening in Judgments of Communication Competence in Co-Workers.

    ERIC Educational Resources Information Center

    Haas, John W.; Arnold, Christa L.

    1995-01-01

    Shows that listening plays a central role in assessments of communication competence, accounting for approximately one-third of the characteristics perceivers use to evaluate communication competence in coworkers. Finds that organization members differ in their use of listening in judgments of communication competence in several kinds of…

  9. More Alike than Different: Early Childhood Professional Development in Guatemala

    ERIC Educational Resources Information Center

    Hardin, Belinda J.; Vardell, Rosemarie; de Castaneda, Albertina

    2008-01-01

    This article describes an early childhood professional development project that took place in the summer of 2005 in Guatemala City. Located in Central America, Guatemala has a population of approximately 12.3 million people, including more than two million children under the age of 5 (UNESCO Institute for Statistics, 2007; UNICEF, 2004). Events…

  10. Genotype identification of human cystic echinococcosis in Isfahan, central Iran.

    PubMed

    Kia, Eshrat Bigom; Rahimi, Hamidreza; Sharbatkhori, Mitra; Talebi, Ardeshir; Fasihi Harandi, Majid; Mirhendi, Hossein

    2010-08-01

    Echinococcosis/hydatidosis is one of the most important zoonotic diseases commonly found in different regions of Iran with a major economic and public health importance. In the current study, Echinococcus granulosus isolates were collected from hospitalized patients in Isfahan, central Iran. The genotypes of 30 samples were determined by polymerase chain reaction amplification of internal transcribed spacer-1 region of ribosomal DNA, followed by restriction fragment length polymorphism (RFLP) with two restriction enzymes namely AluI and MspI. As expected, each isolate yielded an approximately 1-kbp DNA fragment on the electrophoresis gel. According to RFLP results for both enzymes, all isolates had an equal pattern indicating the G1 genotype. Our findings confirmed that G1 is the dominant genotype of cystic echinococcosis in human in central Iran, with predilection to different organs including liver, lung, and brain, and warrants the importance of sheep dog cycle in public health.

  11. Aging changes and gender differences in response to median nerve stimulation measured with MEG.

    PubMed

    Stephen, Julia M; Ranken, Doug; Best, Elaine; Adair, John; Knoefel, Janice; Kovacevic, Sanja; Padilla, Denise; Hart, Blaine; Aine, Cheryl J

    2006-01-01

    The current study uses magnetoencephalography (MEG) to characterize age-related changes and gender differences in the amplitudes and timing of cortical sources evoked by median nerve stimulation. Thirty-four healthy subjects from two age groups: 20-29 and >64 years of age were examined. After measuring the MEG responses, we modeled the data using a spatio-temporal multi-dipole modeling approach to determine the source locations and their associated timecourses. We found early, large amplitude responses in the elderly in primary somatosensory (approximately 20 ms) and pre-central sulcus timecourses (approximately 22 ms) and lower amplitude responses in the elderly later in primary somatosensory (approximately 32 ms) and contralateral secondary somatosensory timecourses (approximately 90 ms). In addition, females had larger peak amplitude responses than males in the contralateral secondary somatosensory timecourse (approximately 28 and 51 ms). These results show that the median nerve stimulation paradigm provides considerable sensitivity to age- and gender-related differences. The results are consistent with the theory that increased amplitudes identified in the elderly may be associated with decreased inhibition. The results emphasize that an examination of two discrete age groups, collapsed across gender, cannot provide a complete understanding of the fundamental changes that occur in the brain across the lifetime.

  12. An Advocate for Every Student at Millard Central Middle School

    ERIC Educational Resources Information Center

    Balkus, Beth

    2006-01-01

    Central Middle School, part of the Millard Public School District, is a grade six through eight urban school located in Omaha, Nebraska. Omaha has a metropolitan and surrounding suburban population of approximately one million. Along with approximately 800 students in traditional middle school teams, CMS also offers a Montessori mini-magnet and…

  13. A computer software system for the generation of global ocean tides including self-gravitation and crustal loading effects

    NASA Technical Reports Server (NTRS)

    Estes, R. H.

    1977-01-01

    A computer software system is described which computes global numerical solutions of the integro-differential Laplace tidal equations, including dissipation terms and ocean loading and self-gravitation effects, for arbitrary diurnal and semidiurnal tidal constituents. The integration algorithm features a successive approximation scheme for the integro-differential system, with time stepping forward differences in the time variable and central differences in spatial variables.

  14. Modular synchronization in complex networks.

    PubMed

    Oh, E; Rho, K; Hong, H; Kahng, B

    2005-10-01

    We study the synchronization transition (ST) of a modified Kuramoto model on two different types of modular complex networks. It is found that the ST depends on the type of intermodular connections. For the network with decentralized (centralized) intermodular connections, the ST occurs at finite coupling constant (behaves abnormally). Such distinct features are found in the yeast protein interaction network and the Internet, respectively. Moreover, by applying the finite-size scaling analysis to an artificial network with decentralized intermodular connections, we obtain the exponent associated with the order parameter of the ST to be beta approximately 1 different from beta(MF) approximately 1/2 obtained from the scale-free network with the same degree distribution but the absence of modular structure, corresponding to the mean field value.

  15. Comparison of Several Dissipation Algorithms for Central Difference Schemes

    NASA Technical Reports Server (NTRS)

    Swanson, R. C.; Radespiel, R.; Turkel, E.

    1997-01-01

    Several algorithms for introducing artificial dissipation into a central difference approximation to the Euler and Navier Stokes equations are considered. The focus of the paper is on the convective upwind and split pressure (CUSP) scheme, which is designed to support single interior point discrete shock waves. This scheme is analyzed and compared in detail with scalar and matrix dissipation (MATD) schemes. Resolution capability is determined by solving subsonic, transonic, and hypersonic flow problems. A finite-volume discretization and a multistage time-stepping scheme with multigrid are used to compute solutions to the flow equations. Numerical results are also compared with either theoretical solutions or experimental data. For transonic airfoil flows the best accuracy on coarse meshes for aerodynamic coefficients is obtained with a simple MATD scheme.

  16. Extraction of business relationships in supply networks using statistical learning theory.

    PubMed

    Zuo, Yi; Kajikawa, Yuya; Mori, Junichiro

    2016-06-01

    Supply chain management represents one of the most important scientific streams of operations research. The supply of energy, materials, products, and services involves millions of transactions conducted among national and local business enterprises. To deliver efficient and effective support for supply chain design and management, structural analyses and predictive models of customer-supplier relationships are expected to clarify current enterprise business conditions and to help enterprises identify innovative business partners for future success. This article presents the outcomes of a recent structural investigation concerning a supply network in the central area of Japan. We investigated the effectiveness of statistical learning theory to express the individual differences of a supply chain of enterprises within a certain business community using social network analysis. In the experiments, we employ support vector machine to train a customer-supplier relationship model on one of the main communities extracted from a supply network in the central area of Japan. The prediction results reveal an F-value of approximately 70% when the model is built by using network-based features, and an F-value of approximately 77% when the model is built by using attribute-based features. When we build the model based on both, F-values are improved to approximately 82%. The results of this research can help to dispel the implicit design space concerning customer-supplier relationships, which can be explored and refined from detailed topological information provided by network structures rather than from traditional and attribute-related enterprise profiles. We also investigate and discuss differences in the predictive accuracy of the model for different sizes of enterprises and types of business communities.

  17. Dose delivered from Varian's CBCT to patients receiving IMRT for prostate cancer.

    PubMed

    Wen, Ning; Guan, Huaiqun; Hammoud, Rabih; Pradhan, Deepak; Nurushev, T; Li, Shidong; Movsas, Benjamin

    2007-04-21

    With the increased use of cone beam CT (CBCT) for daily patient setup, the accumulated dose from CBCT may be significantly higher than that from simulation CT or portal imaging. The objective of this work is to measure the dose from daily pelvic scans with fixed technical settings and collimations. CBCT scans were acquired in half-fan mode using a half bowtie and x-rays were delivered in pulsed-fluoro mode. The skin doses for seven prostate patients were measured on an IRB-approved protocol. TLD capsules were placed on the patient's skin at the central axis of three beams: AP, left lateral (Lt Lat) and right lateral (Rt Lat). To avoid the ring artefacts centred in the prostate, the treatment couch was dropped 3 cm from the patient's tattoo (central axis). The measured AP skin doses ranged 3-6 cGy for 20-33 cm separation. The larger the patient size the less the AP skin dose. Lateral doses did not change much with patient size. The Lt Lat dose was approximately 4.0 cGy, which was approximately 40% higher than the Rt Lat dose of approximately 2.6 cGy. To verify this dose asymmetry, surface doses on an IMRT QA phantom (oval shaped, 30 cm x 20 cm) were measured at the same three sites using TLD capsules with 3 cm table-drop. The dose asymmetry was due to: (1) kV source rotation which always starts from the patient's Lt Lat and ends at Lt Lat. Gantry rotation gets much slower near the end of rotation but dose rate stays constant and (2) 370 degrees scan rotation (10 degrees scan overlap on the Lt Lat side). In vivo doses were measured inside a Rando pelvic heterogeneous phantom using TLDs. The left hip (femoral head and neck) received the highest doses of approximately 10-11 cGy while the right hip received approximately 6-7 cGy. The surface and in vivo doses were also measured for phantoms at the central-axis setup. The difference was less than approximately 12% to the table-drop setup.

  18. 76 FR 22746 - Wiregrass Central Railway, LLC-Acquisition and Operation Exemption-Wiregrass Central Railroad...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-22

    ... Railway, LLC--Acquisition and Operation Exemption--Wiregrass Central Railroad Company, Inc. Wiregrass Central Railway, LLC (WCR), a noncarrier, has filed a verified notice of exemption under 49 CFR 1150.31 to acquire from Wiregrass Central Railroad Company, Inc. (WGCR), and to operate approximately 21.2 miles of...

  19. Time-resolved spectroscopy of dye-labeled photoactive yellow protein suggests a pathway of light-induced structural changes in the N-terminal cap.

    PubMed

    Hoersch, Daniel; Otto, Harald; Cusanovich, Michael A; Heyn, Maarten P

    2009-07-14

    The photoreceptor PYP responds to light activation with global conformational changes. These changes are mainly located in the N-terminal cap of the protein, which is approximately 20 A away from the chromophore binding pocket and separated from it by the central beta-sheet. The question of the propagation of the structural change across the central beta-sheet is of general interest for the superfamily of PAS domain proteins, for which PYP is the structural prototype. Here we measured the kinetics of the structural changes in the N-terminal cap by transient absorption spectroscopy on the ns to second timescale. For this purpose the cysteine mutants A5C and N13C were prepared and labeled with thiol reactive 5-iodoacetamidofluorescein (IAF). A5 is located close to the N-terminus, while N13 is part of helix alpha1 near the functionally important salt bridge E12-K110 between the N-terminal cap and the central anti-parallel beta-sheet. The absorption spectrum of the dye is sensitive to its environment, and serves as a sensor for conformational changes near the labeling site. In both labeled mutants light activation results in a transient red-shift of the fluorescein absorption spectrum. To correlate the conformational changes with the photocycle intermediates of the protein, we compared the kinetics of the transient absorption signal of the dye with that of the p-hydroxycinnamoyl chromophore. While the structural change near A5 is synchronized with the rise of the I(2) intermediate, which is formed in approximately 200 mus, the change near N13 is delayed and rises with the next intermediate I(2)', which forms in approximately 2 ms. This indicates that different parts of the N-terminal cap respond to light activation with different kinetics. For the signaling pathway of photoactive yellow protein we propose a model in which the structural signal propagates from the chromophore binding pocket across the central beta-sheet via the N-terminal region to helix alpha1, resulting in a large change in the protein conformation.

  20. A multigrid LU-SSOR scheme for approximate Newton iteration applied to the Euler equations

    NASA Technical Reports Server (NTRS)

    Yoon, Seokkwan; Jameson, Antony

    1986-01-01

    A new efficient relaxation scheme in conjunction with a multigrid method is developed for the Euler equations. The LU SSOR scheme is based on a central difference scheme and does not need flux splitting for Newton iteration. Application to transonic flow shows that the new method surpasses the performance of the LU implicit scheme.

  1. Identification of influential nodes in complex networks: Method from spreading probability viewpoint

    NASA Astrophysics Data System (ADS)

    Bao, Zhong-Kui; Ma, Chuang; Xiang, Bing-Bing; Zhang, Hai-Feng

    2017-02-01

    The problem of identifying influential nodes in complex networks has attracted much attention owing to its wide applications, including how to maximize the information diffusion, boost product promotion in a viral marketing campaign, prevent a large scale epidemic and so on. From spreading viewpoint, the probability of one node propagating its information to one other node is closely related to the shortest distance between them, the number of shortest paths and the transmission rate. However, it is difficult to obtain the values of transmission rates for different cases, to overcome such a difficulty, we use the reciprocal of average degree to approximate the transmission rate. Then a semi-local centrality index is proposed to incorporate the shortest distance, the number of shortest paths and the reciprocal of average degree simultaneously. By implementing simulations in real networks as well as synthetic networks, we verify that our proposed centrality can outperform well-known centralities, such as degree centrality, betweenness centrality, closeness centrality, k-shell centrality, and nonbacktracking centrality. In particular, our findings indicate that the performance of our method is the most significant when the transmission rate nears to the epidemic threshold, which is the most meaningful region for the identification of influential nodes.

  2. A comparison of two central difference schemes for solving the Navier-Stokes equations

    NASA Technical Reports Server (NTRS)

    Maksymiuk, C. M.; Swanson, R. C.; Pulliam, T. H.

    1990-01-01

    Five viscous transonic airfoil cases were computed by two significantly different computational fluid dynamics codes: An explicit finite-volume algorithm with multigrid, and an implicit finite-difference approximate-factorization method with Eigenvector diagonalization. Both methods are described in detail, and their performance on the test cases is compared. The codes utilized the same grids, turbulence model, and computer to provide the truest test of the algorithms. The two approaches produce very similar results, which, for attached flows, also agree well with experimental results; however, the explicit code is considerably faster.

  3. LANDSAT demonstration/application and GIS integration in south central Alaska

    NASA Technical Reports Server (NTRS)

    Burns, A. W.; Derrenbacher, W.

    1981-01-01

    Automated geographic information systems were developed for two sites in Southcentral Alaska to serve as tests for both the process of integrating classified LANDSAT data into a comprehensive environmental data base and the process of using automated information in land capability/suitability analysis and environmental planning. The Big Lake test site, located approximately 20 miles north of the City of Anchorage, comprises an area of approximately 150 square miles. The Anchorage Hillside test site, lying approximately 5 miles southeast of the central part of the city, extends over an area of some 25 square miles. Map construction and content is described.

  4. Pion properties at finite isospin chemical potential with isospin symmetry breaking

    NASA Astrophysics Data System (ADS)

    Wu, Zuqing; Ping, Jialun; Zong, Hongshi

    2017-12-01

    Pion properties at finite temperature, finite isospin and baryon chemical potentials are investigated within the SU(2) NJL model. In the mean field approximation for quarks and random phase approximation fpr mesons, we calculate the pion mass, the decay constant and the phase diagram with different quark masses for the u quark and d quark, related to QCD corrections, for the first time. Our results show an asymmetry between μI <0 and μI >0 in the phase diagram, and different values for the charged pion mass (or decay constant) and neutral pion mass (or decay constant) at finite temperature and finite isospin chemical potential. This is caused by the effect of isospin symmetry breaking, which is from different quark masses. Supported by National Natural Science Foundation of China (11175088, 11475085, 11535005, 11690030) and the Fundamental Research Funds for the Central Universities (020414380074)

  5. A modified approach to controller partitioning

    NASA Technical Reports Server (NTRS)

    Garg, Sanjay; Veillette, Robert J.

    1993-01-01

    The idea of computing a decentralized control law for the integrated flight/propulsion control of an aircraft by partitioning a given centralized controller is investigated. An existing controller partitioning methodology is described, and a modified approach is proposed with the objective of simplifying the associated controller approximation problem. Under the existing approach, the decentralized control structure is a variable in the partitioning process; by contrast, the modified approach assumes that the structure is fixed a priori. Hence, the centralized controller design may take the decentralized control structure into account. Specifically, the centralized controller may be designed to include all the same inputs and outputs as the decentralized controller; then, the two controllers may be compared directly, simplifying the partitioning process considerably. Following the modified approach, a centralized controller is designed for an example aircraft mode. The design includes all the inputs and outputs to be used in a specified decentralized control structure. However, it is shown that the resulting centralized controller is not well suited for approximation by a decentralized controller of the given structure. The results indicate that it is not practical in general to cast the controller partitioning problem as a direct controller approximation problem.

  6. Metal concentration and X-ray cool spectral component in the central region of the Centaurus cluster of galaxies

    NASA Technical Reports Server (NTRS)

    Fukazawa, Yasushi; Ohashi, Takaya; Fabian, Andrew C.; Canizares, Claude R.; Ikebe, Yasushi; Makishima, Kazuo; Mushotzky, Richard F.; Yamashita, Koujun

    1994-01-01

    Spatially resolved energy spectra in the energy range 0.5-10 keV have been measured for the Centaurus cluster of galaxies with Advanced Satellite for Cosmology and Astrophysics (ASCA). Within 10 min (200 kpc) from the cluster center, the helium-like iron K emission line exhibits a dramatic increase toward the center rising from an equivalent width approximately 500 eV to approximately 1500 eV corresponding to an abundance change from 0.3 to 1.0 solar. The presence of strong iron L lines indicates an additional cool component (kT approximately 1 keV) within 10 min from the center. The cool component requires absorption in excess of the galactic value and this excess absorption increases towards the central region of the cluster. In the surrounding region with radius greater than 10 min, the spectra are well described by a single temperature thermal model with kT approximately 4 keV and spatially uniform abundances at about 0.3-0.4 times solar. The detection of metal-rich hot and cool gas in the cluster center implies a complex nature of the central cluster gas which is likely to be related to the presence of the central cD galaxy NGC 4696.

  7. High-Order Central WENO Schemes for Multi-Dimensional Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bryan (Technical Monitor)

    2002-01-01

    We present new third- and fifth-order Godunov-type central schemes for approximating solutions of the Hamilton-Jacobi (HJ) equation in an arbitrary number of space dimensions. These are the first central schemes for approximating solutions of the HJ equations with an order of accuracy that is greater than two. In two space dimensions we present two versions for the third-order scheme: one scheme that is based on a genuinely two-dimensional Central WENO reconstruction, and another scheme that is based on a simpler dimension-by-dimension reconstruction. The simpler dimension-by-dimension variant is then extended to a multi-dimensional fifth-order scheme. Our numerical examples in one, two and three space dimensions verify the expected order of accuracy of the schemes.

  8. Measurement of the centrality dependence of the charged-particle pseudorapidity distribution in proton-lead collisions at [Formula: see text] TeV with the ATLAS detector.

    PubMed

    Aad, G; Abajyan, T; Abbott, B; Abdallah, J; Abdel Khalek, S; Abdinov, O; Aben, R; Abi, B; Abolins, M; AbouZeid, O S; Abramowicz, H; Abreu, H; Abulaiti, Y; Acharya, B S; Adamczyk, L; Adams, D L; Addy, T N; Adelman, J; Adomeit, S; Adye, T; Agatonovic-Jovin, T; Aguilar-Saavedra, J A; Agustoni, M; Ahlen, S P; Ahmadov, F; Aielli, G; Åkesson, T P A; Akimoto, G; Akimov, A V; Albert, J; Albrand, S; Alconada Verzini, M J; Aleksa, M; Aleksandrov, I N; Alexa, C; Alexander, G; Alexandre, G; Alexopoulos, T; Alhroob, M; Alimonti, G; Alio, L; Alison, J; Allbrooke, B M M; Allison, L J; Allport, P P; Allwood-Spiers, S E; Almond, J; Aloisio, A; Alon, R; Alonso, A; Alonso, F; Alpigiani, C; Altheimer, A; Alvarez Gonzalez, B; Alviggi, M G; Amako, K; Amaral Coutinho, Y; Amelung, C; Ammosov, V V; Amor Dos Santos, S P; Amorim, A; Amoroso, S; Amram, N; Amundsen, G; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anderson, K J; Andreazza, A; Andrei, V; Anduaga, X S; Angelidakis, S; 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Van Nieuwkoop, J; van Vulpen, I; van Woerden, M C; Vanadia, M; Vandelli, W; Vaniachine, A; Vannucci, F; Vardanyan, G; Vari, R; Varnes, E W; Varol, T; Varouchas, D; Vartapetian, A; Varvell, K E; Vazeille, F; Vazquez Schroeder, T; Veatch, J; Veloso, F; Velz, T; Veneziano, S; Ventura, A; Ventura, D; Venturi, M; Venturi, N; Venturini, A; Vercesi, V; Verducci, M; Verkerke, W; Vermeulen, J C; Vest, A; Vetterli, M C; Viazlo, O; Vichou, I; Vickey, T; Vickey Boeriu, O E; Viehhauser, G H A; Viel, S; Vigne, R; Villa, M; Villaplana Perez, M; Vilucchi, E; Vincter, M G; Vinogradov, V B; Virzi, J; Vitells, O; Vivarelli, I; Vives Vaque, F; Vlachos, S; Vladoiu, D; Vlasak, M; Vogel, A; Vokac, P; Volpi, G; Volpi, M; von der Schmitt, H; von Radziewski, H; von Toerne, E; Vorobel, V; Vos, M; Voss, R; Vossebeld, J H; Vranjes, N; Vranjes Milosavljevic, M; Vrba, V; Vreeswijk, M; Vu Anh, T; Vuillermet, R; Vukotic, I; Vykydal, Z; Wagner, P; Wagner, W; Wahrmund, S; Wakabayashi, J; Walder, J; Walker, R; Walkowiak, W; Wall, R; Waller, P; Walsh, B; Wang, C; Wang, C; Wang, F; Wang, H; Wang, H; Wang, J; Wang, J; Wang, K; Wang, R; Wang, S M; Wang, T; Wang, X; Warburton, A; Ward, C P; Wardrope, D R; Warsinsky, M; Washbrook, A; Wasicki, C; Watanabe, I; Watkins, P M; Watson, A T; Watson, I J; Watson, M F; Watts, G; Watts, S; Waugh, A T; Waugh, B M; Webb, S; Weber, M S; Weber, S W; Webster, J S; Weidberg, A R; Weigell, P; Weingarten, J; Weiser, C; Weits, H; Wells, P S; Wenaus, T; Wendland, D; Weng, Z; Wengler, T; Wenig, S; Wermes, N; Werner, M; Werner, P; Wessels, M; Wetter, J; Whalen, K; White, A; White, M J; White, R; White, S; Whiteson, D; Wicke, D; Wickens, F J; Wiedenmann, W; Wielers, M; Wienemann, P; Wiglesworth, C; Wiik-Fuchs, L A M; Wijeratne, P A; Wildauer, A; Wildt, M A; Wilkens, H G; Will, J Z; Williams, H H; Williams, S; Willocq, S; Wilson, A; Wilson, J A; Wingerter-Seez, I; Winkelmann, S; Winklmeier, F; Wittgen, M; Wittig, T; Wittkowski, J; Wollstadt, S J; Wolter, M W; Wolters, H; Wosiek, B K; Wotschack, J; Woudstra, M J; Wozniak, K W; Wright, M; Wu, S L; Wu, X; Wu, Y; Wulf, E; Wyatt, T R; Wynne, B M; Xella, S; Xiao, M; Xu, D; Xu, L; Yabsley, B; Yacoob, S; Yamada, M; Yamaguchi, H; Yamaguchi, Y; Yamamoto, A; Yamamoto, K; Yamamoto, S; Yamamura, T; Yamanaka, T; Yamauchi, K; Yamazaki, Y; Yan, Z; Yang, H; Yang, H; Yang, U K; Yang, Y; Yanush, S; Yao, L; Yasu, Y; Yatsenko, E; Yau Wong, K H; Ye, J; Ye, S; Yen, A L; Yildirim, E; Yilmaz, M; Yoosoofmiya, R; Yorita, K; Yoshida, R; Yoshihara, K; Young, C; Young, C J S; Youssef, S; Yu, D R; Yu, J; Yu, J M; Yu, J; Yuan, L; Yurkewicz, A; Zabinski, B; Zaidan, R; Zaitsev, A M; Zaman, A; Zambito, S; Zanello, L; Zanzi, D; Zaytsev, A; Zeitnitz, C; Zeman, M; Zemla, A; Zengel, K; Zenin, O; Ženiš, T; Zerwas, D; Zevi Della Porta, G; Zhang, D; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, X; Zhang, Z; Zhao, Z; Zhemchugov, A; Zhong, J; Zhou, B; Zhou, L; Zhou, N; Zhu, C G; Zhu, H; Zhu, J; Zhu, Y; Zhuang, X; Zibell, A; Zieminska, D; Zimine, N I; Zimmermann, C; Zimmermann, R; Zimmermann, S; Zimmermann, S; Zinonos, Z; Ziolkowski, M; Zitoun, R; Zobernig, G; Zoccoli, A; Zur Nedden, M; Zurzolo, G; Zutshi, V; Zwalinski, L

    2016-01-01

    The centrality dependence of the mean charged-particle multiplicity as a function of pseudorapidity is measured in approximately 1 [Formula: see text]b[Formula: see text] of proton-lead collisions at a nucleon-nucleon centre-of-mass energy of [Formula: see text] [Formula: see text] using the ATLAS detector at the Large Hadron Collider. Charged particles with absolute pseudorapidity less than 2.7 are reconstructed using the ATLAS pixel detector. The [Formula: see text] collision centrality is characterised by the total transverse energy measured in the Pb-going direction of the forward calorimeter. The charged-particle pseudorapidity distributions are found to vary strongly with centrality, with an increasing asymmetry between the proton-going and Pb-going directions as the collisions become more central. Three different estimations of the number of nucleons participating in the [Formula: see text] collision have been carried out using the Glauber model as well as two Glauber-Gribov inspired extensions to the Glauber model. Charged-particle multiplicities per participant pair are found to vary differently for these three models, highlighting the importance of including colour fluctuations in nucleon-nucleon collisions in the modelling of the initial state of [Formula: see text] collisions.

  9. Measurement of the centrality dependence of the charged-particle pseudorapidity distribution in proton–lead collisions at $$\\sqrt{s_{_\\text {NN}}} = 5.02$$ TeV with the ATLAS detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aad, G.; Abajyan, T.; Abbott, B.

    2016-04-01

    The centrality dependence of the mean charged-particle multiplicity as a function of pseudorapidity is measured in approximately 1 μb -1 of proton–lead collisions at a nucleon–nucleon centre-of-mass energy ofmore » $$\\sqrt{s_{_\\text {NN}}} = 5.02$$ TeV using the ATLAS detector at the Large Hadron Collider. Charged particles with absolute pseudorapidity less than 2.7 are reconstructed using the ATLAS pixel detector. The ρ + Ρb collision centrality is characterised by the total transverse energy measured in the Pb-going direction of the forward calorimeter. The charged-particle pseudorapidity distributions are found to vary strongly with centrality, with an increasing asymmetry between the proton-going and Pb-going directions as the collisions become more central. Three different estimations of the number of nucleons participating in the ρ + Ρb collision have been carried out using the Glauber model as well as two Glauber–Gribov inspired extensions to the Glauber model. In conclusion, charged-particle multiplicities per participant pair are found to vary differently for these three models, highlighting the importance of including colour fluctuations in nucleon–nucleon collisions in the modelling of the initial state of ρ + Ρb collisions.« less

  10. Observations of Environmental Quenching in Groups in the 11 GYR Since z = 2.5: Different Quenching For Central and Satellite Galaxies

    NASA Technical Reports Server (NTRS)

    Tal, Tomer; Dekel, Avishai; Marchesini, Danilo; Momcheva, Ivelina; Nelson, Erica J.; Patel, Shannon G.; Quadri, Ryan F.; Rix, Hans-Walter; Skelton, Rosalind E.; Wake, David A.; hide

    2014-01-01

    We present direct observational evidence for star formation quenching in galaxy groups in the redshift range 0 less than z less than 2.5. We utilize a large sample of nearly 6000 groups, selected by fixed cumulative number density from three photometric catalogs, to follow the evolving quiescent fractions of central and satellite galaxies over roughly 11 Gyr. At z approximately 0, central galaxies in our sample range in stellar mass from Milky Way/M31 analogs (M=6.5x10(exp 10) M/solar mass) to nearby massive ellipticals (M=1.5x10(exp 11) M/solar mass). Satellite galaxies in the same groups reach masses as low as twice that of the Large Magellanic Cloud (M=6.5x10(exp 9) M/solar mass). Using statistical background subtraction, we measure the average rest-frame colors of galaxies in our groups and calculate the evolving quiescent fractions of centrals and satellites over seven redshift bins. Our analysis shows clear evidence for star formation quenching in group halos, with a different quenching onset for centrals and their satellite galaxies. Using halo mass estimates for our central galaxies, we find that star formation shuts off in centrals when typical halo masses reach between 10(exp 12) and 10(exp 13) M/solar mass, consistent with predictions from the halo quenching model. In contrast, satellite galaxies in the same groups most likely undergo quenching by environmental processes, whose onset is delayed with respect to their central galaxy. Although star formation is suppressed in all galaxies over time, the processes that govern quenching are different for centrals and satellites. While mass plays an important role in determining the star formation activity of central galaxies, quenching in satellite galaxies is dominated by the environment in which they reside.

  11. Identification of catalytic residues of a very large NAD-glutamate dehydrogenase from Janthinobacterium lividum by site-directed mutagenesis.

    PubMed

    Kawakami, Ryushi; Sakuraba, Haruhiko; Ohshima, Toshihisa

    2014-01-01

    We previously found a very large NAD-dependent glutamate dehydrogenase with approximately 170 kDa subunit from Janthinobacterium lividum (Jl-GDH) and predicted that GDH reaction occurred in the central domain of the subunit. To gain further insights into the role of the central domain, several single point mutations were introduced. The enzyme activity was completely lost in all single mutants of R784A, K810A, K820A, D885A, and S1142A. Because, in sequence alignment analysis, these residues corresponded to the residues responsible for glutamate binding in well-known small GDH with approximately 50 kDa subunit, very large GDH and well-known small GDH may share the same catalytic mechanism. In addition, we demonstrated that C1141, one of the three cysteine residues in the central domain, was responsible for the inhibition of enzyme activity by HgCl2, and HgCl2 functioned as an activating compound for a C1141T mutant. At low concentrations, moreover, HgCl2 was found to function as an activating compound for a wild-type Jl-GDH. This suggests that the mechanism for the activation is entirely different from that for the inhibition.

  12. Quasi-planar elemental clusters in pair interactions approximation

    NASA Astrophysics Data System (ADS)

    Chkhartishvili, Levan

    2016-01-01

    The pair-interactions approximation, when applied to describe elemental clusters, only takes into account bonding between neighboring atoms. According to this approach, isomers of wrapped forms of 2D clusters - nanotubular and fullerene-like structures - and truly 3D clusters, are generally expected to be more stable than their quasi-planar counterparts. This is because quasi-planar clusters contain more peripheral atoms with dangling bonds and, correspondingly, fewer atoms with saturated bonds. However, the differences in coordination numbers between central and peripheral atoms lead to the polarization of bonds. The related corrections to the molar binding energy can make small, quasi-planar clusters more stable than their 2D wrapped allotropes and 3D isomers. The present work provides a general theoretical frame for studying the relative stability of small elemental clusters within the pair interactions approximation.

  13. Structural characterization of a novel neuropeptide from the central nervous system of the leech Erpobdella octoculata. The leech osmoregulator factor.

    PubMed

    Salzet, M; Bulet, P; Weber, W M; Clauss, W; Verger-Bocquet, M; Malecha, J

    1996-03-22

    Purification of a material immunoreactive to an antiserum against the C-terminal part of the oxytocin (Pro-Leu-Gly-amide) and present in the central nervous system of the Pharyngobdellid leech Erpobdella octoculata was performed by reversed-phase high performance liquid chromatography combined with both enzyme-linked immunosorbent and dot immunobinding assays for oxytocin. The amino acid sequence of the purified peptide (Ile-Pro-Glu-Pro-Tyr-Val-Trp-Asp) was established by Edman degradation and confirmed by electrospray mass spectrometry measurement. When injected in leeches, purified or synthetic peptides exert an anti-diuretic effect, the most effective ranged between 10 pmol and 1 nmol. They provoked an uptake of water 1-2 h post-injection. Furthermore, electrophysiological experiments conducted in the leech Hirudo medicinalis revealed an inhibition of the potency of Na+ conductances of leech skin by this peptide. Immunocytochemical studies with an antiserum against synthetic oxytocin-like molecule provided the cytological basis for existence of a neuropeptide, since large amounts of immunoreactive neurons were detected in the central nervous systems of E. octoculata. The purified molecule is both different to peptides of the oxytocin/vasopressin family and is a novel neuropeptide in the animal kingdom. It was named the leech osmoregulator factor (LORF). An identification of the proteins immunoreactive to an antiserum against oxytocin performed at the level of both central nervous systems extracts and in vitro central nervous system-translated RNA products indicated that in the two cases, a single protein was detected. These proteins with a molecular masses of, respectively, approximately 34 kDa (homodimer of 17 kDa) for the central nervous systems extracts and approximately 19 kDa for in vitro central nervous system-translated RNA products were not recognized by the antiserum against MSEL- and VLDV-neurophysin (proteins associated to oxytocin and vasopressin), confirming that LORF did not belong to the oxytocin/vasopressin family.

  14. Reclaiming the Periphery: Automated Kinetic Perimetry for Measuring Peripheral Visual Fields in Patients With Glaucoma.

    PubMed

    Mönter, Vera M; Crabb, David P; Artes, Paul H

    2017-02-01

    Peripheral vision is important for mobility, balance, and guidance of attention, but standard perimetry examines only <20% of the entire visual field. We report on the relation between central and peripheral visual field damage, and on retest variability, with a simple approach for automated kinetic perimetry (AKP) of the peripheral field. Thirty patients with glaucoma (median age 68, range 59-83 years; median Mean Deviation -8.0, range -16.3-0.1 dB) performed AKP and static automated perimetry (SAP) (German Adaptive Threshold Estimation strategy, 24-2 test). Automated kinetic perimetry consisted of a fully automated measurement of a single isopter (III.1.e). Central and peripheral visual fields were measured twice on the same day. Peripheral and central visual fields were only moderately related (Spearman's ρ, 0.51). Approximately 90% of test-retest differences in mean isopter radius were < ±4 deg. Relative to the range of measurements in this sample, the retest variability of AKP was similar to that of SAP. Patients with similar central visual field loss can have strikingly different peripheral visual fields, and therefore measuring the peripheral visual field may add clinically valuable information.

  15. Structural and lithographic study of northern coast ranges and Sacramento Valley, California

    NASA Technical Reports Server (NTRS)

    Rich, E. I. (Principal Investigator)

    1973-01-01

    The author has identified the following significant results. The analysis of the ERTS data has disclosed three potentially important linear systems within the northern coast ranges and Sacramento Valley, California. A preliminary geomorphic analysis of the northern coast ranges discloses that the geomorphic characteristics of the area underlain by the Coastal system are much different from those associated with the Central system in the core of the Coast Ranges. Within the Coastal system, or Coastal belt, the drainage networks are moderately fine-textured and have moderately high density. The area associated with the Central system seems to be underlain by an heterogeneous assemblage of rock types which vary in their resistance to erosion. The boundary between the Coastal and Central geomorphic regions is poorly defined and, in a few places, the two regions can be separated only approximately.

  16. High-Order Semi-Discrete Central-Upwind Schemes for Multi-Dimensional Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bran R. (Technical Monitor)

    2002-01-01

    We present high-order semi-discrete central-upwind numerical schemes for approximating solutions of multi-dimensional Hamilton-Jacobi (HJ) equations. This scheme is based on the use of fifth-order central interpolants like those developed in [1], in fluxes presented in [3]. These interpolants use the weighted essentially nonoscillatory (WENO) approach to avoid spurious oscillations near singularities, and become "central-upwind" in the semi-discrete limit. This scheme provides numerical approximations whose error is as much as an order of magnitude smaller than those in previous WENO-based fifth-order methods [2, 1]. Thee results are discussed via examples in one, two and three dimensions. We also pregnant explicit N-dimensional formulas for the fluxes, discuss their monotonicity and tl!e connection between this method and that in [2].

  17. Growth status and estimated growth rate of youth football players: a community-based study.

    PubMed

    Malina, Robert M; Morano, Peter J; Barron, Mary; Miller, Susan J; Cumming, Sean P

    2005-05-01

    To characterize the growth status of participants in community-sponsored youth football programs and to estimate rates of growth in height and weight. Mixed-longitudinal over 2 seasons. Two communities in central Michigan. Members of 33 youth football teams in 2 central Michigan communities in the 2000 and 2001 seasons (Mid-Michigan PONY Football League). Height and weight of all participants were measured prior to each season, 327 in 2000 and 326 in 2001 (n = 653). The body mass index (kg/m) was calculated. Heights and weights did not differ from season to season and between the communities; the data were pooled and treated cross-sectionally. Increments of growth in height and weight were estimated for 166 boys with 2 measurements approximately 1 year apart to provide an estimate of growth rate. Growth status (size-attained) of youth football players relative to reference data (CDC) for American boys and estimated growth rate relative to reference values from 2 longitudinal studies of American boys. Median heights of youth football players approximate the 75th percentiles, while median weights approximate the 75th percentiles through 11 years and then drift toward the 90th percentiles of the reference. Median body mass indexes of youth football players fluctuate about the 85th percentiles of the reference. Estimated growth rates in height approximate the reference and may suggest earlier maturation, while estimated growth rates in weight exceed the reference. Youth football players are taller and especially heavier than reference values for American boys. Estimated rates of growth in height approximate medians for American boys and suggest earlier maturation. Estimated rates of growth in weight exceed those of the reference and may place many youth football players at risk for overweight/obesity, which in turn may be a risk factor for injury.

  18. Two-component gravitating systems and the red giant-like structure

    NASA Technical Reports Server (NTRS)

    Fujimoto, Masayuki Y.; Tomisaka, Kohji

    1992-01-01

    The present study investigates the equilibria and evolution of gravitating systems composed of two components by approximating their equations of states to polytropes. The structures are explored in hydrostatic equilibrium systematically under the condition that two components interact with each other only through gravity. The systems are found to be characterized by four parameters, the ratio of central densities and the ratio of central thermal energies per unit mass, and the polytropic indices of two components. If the central density is much higher, the structure is little affected by the presence of the other component. If the difference in the central thermal energies is smaller than specified by beta-cri, the system adopts an equilibrium configuration for any mass ratio. Two-component systems necessarily evolve to have the red giantlike structure if one component suffers cooling faster than the other. It is concluded that the red giant structure is a general characteristic of gravitating systems for which there is an appropriate mechanism to decouple the constituent into the hotter and cooler components.

  19. Spline smoothing of histograms by linear programming

    NASA Technical Reports Server (NTRS)

    Bennett, J. O.

    1972-01-01

    An algorithm for an approximating function to the frequency distribution is obtained from a sample of size n. To obtain the approximating function a histogram is made from the data. Next, Euclidean space approximations to the graph of the histogram using central B-splines as basis elements are obtained by linear programming. The approximating function has area one and is nonnegative.

  20. Racial differences in diabetes among Union Forces during the US Civil War.

    PubMed

    Smith, Jeffrey A; Frueh, B Christopher; Campbell, Jennifer; Egede, Leonard

    2015-01-01

    Diabetes is the seventh leading cause of death in the United States and disproportionately affects ethnic minorities. While research examining health disparities is well-established, an historical understanding of how the disparities evolved over time may be warranted. This article examined racial differences in prevalence of diabetes and associated mortality in Blacks and Whites during the US Civil War. Data were extracted from the Medical and Surgical History of the War of Rebellion, 1861-1865, representing segregated White and Black Union Forces who served during the war. Data were collapsed by war theater (Atlantic, Central, Pacific). Results by race show that, from 1861 to 1866, the rates of Whites diagnosed with diabetes ranged overall from 0% to .11% and was distributed throughout the war theaters as: Atlantic 0.3% to .05%; Central 0.3% to .08%, and Pacific 0% to .11%. For Blacks, Atlantic ranged from .02% to .07% and Central .03% to .06%. None were reported for Pacific. Mortality was approximately .01% for both Blacks and Whites. These data suggest no racial differences in diabetes prevalence and mortality existed between Blacks and Whites during this time, implying that disparities may have evolved more recently.

  1. First International Conference on Numerical Ship Hydrodynamics Held in Gaithersburg, Maryland on 20-22 October 1975.

    DTIC Science & Technology

    1975-01-01

    instance, Harlow and Amsden, 1971 ). In this method a staggered finite difference mesh as shown in Figure 2 is used. 4X 1X 41X 0X 4 - -* - 4 - * - 4 - -X I...in Harlow and Amsden ( 1971 ). It suffices to state here that spatial derivatives are approximated by central differences throughout giving 0(h 2...flow divergence.) The boundary conditions are not elaborated here (but see Harlow and Amsden, 1971 ) except to note that the free surface is advanced

  2. 78 FR 23633 - Union Pacific Railroad Company-Trackage Rights Exemption-Illinois Central Railroad Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... Railroad Company--Trackage Rights Exemption-- Illinois Central Railroad Company Illinois Central Railroad... trackage rights to Union Pacific Railroad Company (UP) over IC's Chicago Subdivision between milepost 21.0... predecessor railroads, it currently maintains trackage rights over approximately 60 miles of IC's rail line...

  3. 75 FR 63540 - Norfolk Southern Railway Company-Trackage Rights Exemption-Illinois Central Railroad Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Railway Company--Trackage Rights Exemption-- Illinois Central Railroad Company Pursuant to a written trackage rights agreement dated August 17, 2010, Illinois Central Railroad Company (IC) has agreed to grant overhead trackage rights to Norfolk Southern Railroad Company (NSR) over approximately 199.1 miles of rail...

  4. 77 FR 11192 - Cedar River Railroad Company-Trackage Rights Exemption-Chicago, Central & Pacific Railroad Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... Railroad Company--Trackage Rights Exemption--Chicago, Central & Pacific Railroad Company Pursuant to a written trackage rights agreement,\\1\\ Chicago, Central & Pacific Railroad Company (CCP) has agreed to grant nonexclusive overhead trackage rights to Cedar River Railroad Company (CEDR) over approximately 5...

  5. Conodonts of the Mississippian/Pennsylvanian boundary interval in Central Iran

    NASA Astrophysics Data System (ADS)

    Bahrami, A.; Boncheva, I.; Königshof, P.; Yazdi, M.; Ebrahimi Khan-Abadi, A.

    2014-10-01

    The record of conodonts related to the Mississippian/Pennsylvanian boundary interval was investigated in four sections in Central Iran from two different structural units. Two sections from the Sanandaj-Sirjan trend zone (Asad-abad, and Darchaleh sections) and two from the East-Central Iran Microplate (Shesh-angosht and Kale-Sardar sections) exhibit a nearly complete record previously described across the Mississippian/Pennsylvanian boundary in Iran. The investigated sections can be subdivided in three formations (Ghaleh-, Absheni-, and Zaluda Formation) which belong to the Sardar Group. The mid-Carboniferous boundary was defined by the occurrence of Declinognathus noduliferus s.l.. Bio-event characteristics of the Carboniferous conodont fauna (Mississippian genera Gnathodus and Lochriea have been replaced by Pennsylvanian genera Declinognathus and Idiognathodus) as well as sedimentological changes within overall shallow water deposits were located approximately 33° S of the paleoequator and suggest sea-level changes within the framework of the Late Paleozoic Ice Age (LPIA). Furthermore, a widespread crinoid marker horizon previously described from two localities in Iran can be subdivided into three units of different ages.

  6. Stochastic differential equation model for linear growth birth and death processes with immigration and emigration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Granita, E-mail: granitafc@gmail.com; Bahar, A.

    This paper discusses on linear birth and death with immigration and emigration (BIDE) process to stochastic differential equation (SDE) model. Forward Kolmogorov equation in continuous time Markov chain (CTMC) with a central-difference approximation was used to find Fokker-Planckequation corresponding to a diffusion process having the stochastic differential equation of BIDE process. The exact solution, mean and variance function of BIDE process was found.

  7. Dose profile variation with voltage in head CT scans using radiochromic films

    NASA Astrophysics Data System (ADS)

    Mourão, A. P.; Alonso, T. C.; DaSilva, T. A.

    2014-02-01

    The voltage source used in an X-ray tube is an important part of defining the generated beam spectrum energy profile. The X-ray spectrum energy defines the X-ray beam absorption as well as the characteristics of the energy deposition in an irradiated object. Although CT scanners allow one to choose between four different voltage values, most of them employ a voltage of 120 kV in their scanning protocols, regardless of the patient characteristics. Based on this fact, this work investigated the deposited dose in a polymethyl methacrylate (PMMA) cylindrical head phantom. The entire volume was irradiated twice. Two CT scanning protocols were used with two different voltage values: 100 and 120 kV. The phantom volume was irradiated, and radiochromic films were employed to record dose profiles. Measurements were conducted with a calibrated pencil ionization chamber, which was positioned in the center and in four peripheral bores of the head PMMA phantom, to calibrate the radiochromic films. The central slice was then irradiated. This procedure allowed us to find the conversion factors necessary to obtain dose values recorded in the films. The data obtained allowed us to observe the dose variation profile inside the phantom head as well as in the peripheral and central regions. The peripheral region showed higher dose values than those of the central region for scans using both voltage values: approximately 31% higher for scanning with 120 kV and 25% higher with 100 kV. Doses recorded with the highest voltage are significantly higher, approximately 50% higher in the peripheral region and 40% higher in the central region. A longitudinal variation could be observed, and the maximum dose was recorded at the peripheral region, at the midpoint of the longitudinal axis. The obtained results will most likely contribute to the dissemination of proper procedure as well as to optimize dosimetry and tests of quality control in CT because the choice of protocols with different voltage values can be a way to optimize the CT scans.

  8. A simple low-computation-intensity model for approximating the distribution function of a sum of non-identical lognormals for financial applications

    NASA Astrophysics Data System (ADS)

    Messica, A.

    2016-10-01

    The probability distribution function of a weighted sum of non-identical lognormal random variables is required in various fields of science and engineering and specifically in finance for portfolio management as well as exotic options valuation. Unfortunately, it has no known closed form and therefore has to be approximated. Most of the approximations presented to date are complex as well as complicated for implementation. This paper presents a simple, and easy to implement, approximation method via modified moments matching and a polynomial asymptotic series expansion correction for a central limit theorem of a finite sum. The method results in an intuitively-appealing and computation-efficient approximation for a finite sum of lognormals of at least ten summands and naturally improves as the number of summands increases. The accuracy of the method is tested against the results of Monte Carlo simulationsand also compared against the standard central limit theorem andthe commonly practiced Markowitz' portfolio equations.

  9. Evaluation of residue management practices effects on corn productivity, soil quality, and greenhouse gas emissions

    NASA Astrophysics Data System (ADS)

    Guzman, Jose German

    The removal of crop residues left after harvest is being considered as a potential feedstock source for bioethanol production which can contribute to the reduction of fossil fuel use and net greenhouse gas (GHG). The objectives of this study were to: (i) examine how tillage, N fertilization rates, residue removal, and their interactions affect crop productivity, (ii) SOC and soil physical properties, and (iii) GHG emissions, and (iv) calculated a soil C budget to determine how much crop residue can be sustainably be removed in Central and Southwest Iowa. After three years of residue removal under different management practices, the findings of this study suggest that a portion of the corn residue that is left on the soil surface after harvest can be removed, with no negative impacts in the short term continuous corn yield in sites at Central and Southwest Iowa. However, significant decreases in SOC sequestration rates, microbial biomass-C, bulk density, soil penetration resistance, wet aggregate stability, and infiltration rates were observed, but varied with soil type and management practices. Additionally, soil surface CO2 and N2O emissions were responsive to management practices; primarily by altering soil temperature, soil water content, soil mineral N, and crop growth. Results from soil C budget show that in 2010 when corn growth was not water stressed (lack of moisture), approximately 35 and 30% of the residue could be sustainably removed in the Central and Southwest sites, respectively. In 2011, drier soil conditions resulted in approximately 2 and 49% of the residue could be sustainably removed in the Central and Southwest sites, respectively.

  10. Centrality dependence of particle production in p - Pb collisions at s NN = 5.02 TeV

    DOE PAGES

    Adam, J.; Adamová, D.; Aggarwal, M. M.; ...

    2015-06-08

    Here, we report measurements of the primary charged-particle pseudorapidity density and transverse momentum distributions in p–Pb collisions at √s NN = 5.02TeV and investigate their correlation with experimental observables sensitive to the centrality of the collision. Centrality classes are defined by using different event-activity estimators, i.e., charged-particle multiplicities measured in three different pseudorapidity regions as well as the energy measured at beam rapidity (zero degree). The procedures to determine the centrality, quantified by the number of participants (N part) or the number of nucleon-nucleon binary collisions (N coll) are described. We show that, in contrast to Pb-Pb collisions, in p–Pbmore » collisions large multiplicity fluctuations together with the small range of participants available generate a dynamical bias in centrality classes based on particle multiplicity. We propose to use the zero-degree energy, which we expect not to introduce a dynamical bias, as an alternative event-centrality estimator. Based on zero-degree energy-centrality classes, the N part dependence of particle production is studied. Under the assumption that the multiplicity measured in the Pb-going rapidity region scales with the number of Pb participants, an approximate independence of the multiplicity per participating nucleon measured at mid-rapidity of the number of participating nucleons is observed. Furthermore, at high-p T the p–Pb spectra are found to be consistent with the pp spectra scaled by N coll for all centrality classes. Our results represent valuable input for the study of the event-activity dependence of hard probes in p–Pb collisions and, hence, help to establish baselines for the interpretation of the Pb-Pb data.« less

  11. Effectiveness of TAD-anchored maxillary protraction in late mixed dentition.

    PubMed

    Feng, Xiaoxia; Li, Jianhua; Li, Yu; Zhao, Zhihe; Zhao, Sen; Wang, Jue

    2012-11-01

    To evaluate the effectiveness of temporary anchorage device (TAD)-anchored maxillary protraction (MP) in terms of the skeletal and dentoalveolar changes and to compare it with traditional tooth-anchored MP. A computerized literature search for relative randomized controlled trials and prospective controlled trials was performed in PubMed, MEDLINE, Cochrane Central Register of Controlled Trials, Embase, CNKI, and Google Scholar, complemented with manual search. Data extraction and quality assessment were carried out by two reviewers independently. Meta-analysis was followed when possible; otherwise, description was done. Forty articles were found, among which four trials were qualified for meta-analysis. The results showed that there was significant difference between TAD-anchored MP and untreated control in terms of maxillary advancement (weighted mean differences (WMD) 3.08 mm; 95% CI: 1.61 to approximately 4.56; P < .0001), but there were no consistent points in terms of mandibular rotation. Also, there were significant differences between both treatment patterns regarding maxillary advancement (WMD 1.41 mm; 95% CI: 0.47 to approximately 2.35; P  =  .003), mandibular rotation (WMD -1.39°, 95% CI: -2.47 to approximately -0.31; P  =  .01), proclination of maxillary incisors (WMD -2.29°; 95% CI: -4.41 to approximately -0.17; P  =  .03), and extrusion of maxillary molars (WMD -1.68 mm; 95% CI: -2.51 to approximately -0.85; P < .0001). According to the present results, TAD-anchored MP might have a greater maxillary advancement effect and might reduce skeletal and dental side effects, compared with tooth-anchored MP.

  12. Human land use influences chronic wasting disease prevalence in mule deer

    USGS Publications Warehouse

    Farnsworth, Matthew L.; Wolfe, L.L.; Hobbs, N.T.; Burnham, K.P.; Williams, E.S.; Theobald, D.M.; Conner, M.M.; Miller, M.W.

    2005-01-01

    Human alteration of landscapes can affect the distribution, abundance, and behavior of wildlife. We explored the effects of human land use on the prevalence of chronic wasting disease (CWD) in mule deer (Odocoileus hemionus) populations residing in north-central Colorado. We chose best approximating models estimating CWD prevalence in relation to differences in human land use, sex, and geographic location. Prevalence was higher in developed areas and among male deer, suggesting anthropogenic influences on the occurrence of disease. We also found a relatively high degree of variation in prevalence across the three study sites, suggesting that spatial patterns in disease may be influenced by other factors operating at a broader, landscape scale. Our results suggest that multiple factors, including changes in land use, differences in exposure risk between sexes, and landscape-scaled heterogeneity, are associated with CWD prevalence in north-central Colorado.

  13. Pacifier Stiffness Alters the Dynamics of the Suck Central Pattern Generator.

    PubMed

    Zimmerman, Emily; Barlow, Steven M

    2008-06-01

    Variation in pacifier stiffness on non-nutritive suck (NNS) dynamics was examined among infants born prematurely with a history of respiratory distress syndrome. Three types of silicone pacifiers used in the NICU were tested for stiffness, revealing the Super Soothie™ nipple is 7 times stiffer than the Wee™ or Soothie™ pacifiers even though shape and displaced volume are identical. Suck dynamics among 20 preterm infants were subsequently sampled using the Soothie™ and Super Soothie™ pacifiers during follow-up at approximately 3 months of age. ANOVA revealed significant differences in NNS cycles/min, NNS amplitude, NNS cycles/burst, and NNS cycle periods as a function of pacifier stiffness. Infants modify the spatiotemporal output of their suck central pattern generator when presented with pacifiers with significantly different mechanical properties. Infants show a non-preference to suck due to high stiffness in the selected pacifier. Therefore, excessive pacifier stiffness may decrease ororhythmic patterning and impact feeding outcomes.

  14. Pacifier Stiffness Alters the Dynamics of the Suck Central Pattern Generator

    PubMed Central

    Zimmerman, Emily; Barlow, Steven M.

    2008-01-01

    Variation in pacifier stiffness on non-nutritive suck (NNS) dynamics was examined among infants born prematurely with a history of respiratory distress syndrome. Three types of silicone pacifiers used in the NICU were tested for stiffness, revealing the Super Soothie™ nipple is 7 times stiffer than the Wee™ or Soothie™ pacifiers even though shape and displaced volume are identical. Suck dynamics among 20 preterm infants were subsequently sampled using the Soothie™ and Super Soothie™ pacifiers during follow-up at approximately 3 months of age. ANOVA revealed significant differences in NNS cycles/min, NNS amplitude, NNS cycles/burst, and NNS cycle periods as a function of pacifier stiffness. Infants modify the spatiotemporal output of their suck central pattern generator when presented with pacifiers with significantly different mechanical properties. Infants show a non-preference to suck due to high stiffness in the selected pacifier. Therefore, excessive pacifier stiffness may decrease ororhythmic patterning and impact feeding outcomes. PMID:19492006

  15. Hematology and plasma biochemistry values for the giant garter snake (Thamnophis gigas) and valley garter snake (Thamnophis sirtalis fitchi) in the Central Valley of California.

    PubMed

    Wack, Raymund F; Hansen, Eric; Small, Marilyn; Poppenga, Robert; Bunn, David; Johnson, Christine K

    2012-04-01

    Hematology and plasma biochemistry parameters are useful in the assessment and management of threatened and endangered species. Although reference ranges are readily available for many mammalian species, reference ranges for snakes are lacking for most species. We determined hematology and plasma biochemistry reference ranges for giant garter snakes (Thamnophis gigas) and valley garter snakes (Thamnophis sirtalis fitchi) living in four management areas in the Central Valley of California. White blood cell, heterophil, lymphocyte, and azurophil counts in giant garter snakes were approximately twice the values of valley garter snakes. Statistically significant differences in aspartate aminotransferase, globulin, and potassium between the two species did not appear clinically significant. No significant differences were found in the measured parameters between male and female giant garter snakes. Some differences were found among collection sites. These reference ranges provide baseline data for comparisons over time and between collection sites.

  16. Single-dose effects of isosorbide mononitrate alone or in combination with losartan on central blood pressure.

    PubMed

    Kaufman, Rhonda; Nunes, Irene; Bolognese, James A; Miller, Deborah L; Salotti, Dennis; McCarthy, Jennifer M; Smith, William B; Herman, Gary A; Feig, Peter U

    2010-01-01

    Antihypertensive drugs can have different effects on central and brachial blood pressures, which may affect outcomes. Nitric oxide donors have acute effects on central blood pressure but have not been assessed with renin-angiotensin system blockade. Thirteen patients with prehypertensive/Stage 1 hypertension were randomized to five single-dose treatments separated by ≤4 days using a double-blind, crossover study design: angiotensin receptor blocker (ARB) losartan 100 mg, isosorbide mononitrate (ISMN) 60 mg, losartan 100 mg + ISMN 15 mg, losartan 100 mg + ISMN 60 mg, and placebo. Central and brachial blood pressures were measured throughout 10 hours. Mean placebo-subtracted decrease from baseline in augmentation index (AIx) approximately 1% for losartan 100 mg, 26% for ISMN 60 mg, 19% for losartan 100 mg + ISMN 15 mg, and 24% for losartan 100 mg + ISMN 60 mg. Administered with losartan 100 mg or alone, ISMN lowered AIx, demonstrating that acute effects of a nitrate donor are much larger than those of an ARB even when administered with an ARB. Differences from placebo were statistically significant except for losartan 100 mg. AIx is a good biomarker of acute hemodynamic effects of nitric oxide in prehypertensive/Stage 1 hypertension. 2010 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.

  17. Neutral hydrogen and optical properties of three amorphous galaxies

    NASA Technical Reports Server (NTRS)

    Hunter, Deidre A.; Woerden, Hugo Van; Gallagher, John S., III

    1994-01-01

    We present new interferometric H I and optical observations of three amorphous galaxies, systems with a smooth, high surface brightness but an asymmetrical distribution of light. All three galaxies are forming stars and have LMC-like emission-line ratios, low dust content, and high H I velocity dispersions. NGC 1140 has a boxy inner morphology with a hook off one corner. At low light levels unusual extensions of starlight are seen curving to the northwest and southeast. The galaxy contains a very luminous central star-forming region and a small chain of H II regions that coincide with the hook. The central H II region has broad H(alpha) velocity profiles full width at half maximum (FWHM) less than or equal to 140 km/s, and it is a radio continuum source. There is a rotating H I gas disk, 40 kpc in radius, at a position angle 51 deg from the optical major axis. The central gas ridge follows the chain of H II regions, and the H I peak is on the hook. The outer gas on the southeast side curves away from the H I major axis. The central gas density is high, and the surface density declines very slowly with radius. The rotation velocity yields a mass of 1 x 10(exp 11) solar mass at 3.3 Holmberg radii (R(sub H)). NGC 1800 has a hook that coincides with a large H II region, and an r(exp 1/4) luminosity distribution. There are numerous H II regions along the major axis and extraordinary filaments of ionized gas. Emanating from the major axis on either side of the galaxy are H(alpha) fingers approximately 750 pc long. About 2.3 kpc to the north is a web of filaments approximately 3 kpc in extent. H(alpha) profiles of H II regions and filaments are narrow. The H I gas disk has a position angle that is approximately 13 deg different from that of the optical axis. There are two peaks near the center, one of which is near the largest H II region. Beyond the Holmberg radius to the west is a 6 x 10(exp 6) solar mass H I cloud. Its velocity indicates a mass of approximately 6 x 10(exp 9) solar mass for NGC 1800 at 1.5 R(sub H). At approximately R(sub 25) to the east there is a large H I shell. Also at approximately R(sub 25) on both sides the velocity gradient switches by 90 deg, and in the interior the rotation is about the major axis. The central gas density is low and falls off slowly. In the inner regions NGC 4670 resembles an S0/a galaxy seen rather edge-on. It contains a central supergiant H II region with very high velocity widths (FWHM less than or equal to 180 km/s) and complex velocity structures. It is a radio continuum source as well. The H I gas is a single spherical cloud or a disk at low inclination centered on the galaxy with a slight elongation along the optical major axis and rotation about the minor axis. The central gas density is high, and there is a high degree of concentration. The rotation speed indicates a total mass of 5 x 10(exp 10) solar mass at 1.1 R(sub H). We compare these characteristics with properties of gas in the presence of stellar bar potentials, gas warps, and interacting and merging galaxy models. Although there are inconsistencies and uncertainties, we conclude that NGC 1140 is a spiral of low surface brightness that has undergone a merger, while NGC 1800 and NGC 4670 are, respectively, probably an Im system and a spiral that had an encounter of the Noguchi (1988a) kind.

  18. Low Vision Rehabilitation Intervention for People with Ring Scotomas

    ERIC Educational Resources Information Center

    Schoessow, Kimberly A.; Gilbert, Leah M.; Jackson, Mary Lou

    2010-01-01

    Central scotomas--areas of the nonseeing retina within the central 20 degrees of the visual field--are present in approximately 90% of vision rehabilitation patients. They vary in size and shape and can be small or large, symmetrical or asymmetrical, round or irregularly shaped. Most central scotomas border fixation on one side and can be overcome…

  19. Three-dimensional simulation of vortex breakdown

    NASA Technical Reports Server (NTRS)

    Kuruvila, G.; Salas, M. D.

    1990-01-01

    The integral form of the complete, unsteady, compressible, three-dimensional Navier-Stokes equations in the conservation form, cast in generalized coordinate system, are solved, numerically, to simulate the vortex breakdown phenomenon. The inviscid fluxes are discretized using Roe's upwind-biased flux-difference splitting scheme and the viscous fluxes are discretized using central differencing. Time integration is performed using a backward Euler ADI (alternating direction implicit) scheme. A full approximation multigrid is used to accelerate the convergence to steady state.

  20. Triple Asteroid System Triples Asteroid Observers Interest

    NASA Image and Video Library

    2009-08-06

    NASA Deep Space Network, Goldstone radar images show triple asteroid 1994 CC, which consists of a central object approximately 700 meters 2,300 feet in diameter and two smaller moons that orbit the central body. Animation available at the Photojournal

  1. A Study of Calculus Instructors' Perceptions of Approximation as a Unifying Thread of the First-Year Calculus

    ERIC Educational Resources Information Center

    Sofronas, Kimberly S.; DeFranco, Thomas C.; Swaminathan, Hariharan; Gorgievski, Nicholas; Vinsonhaler, Charles; Wiseman, Brianna; Escolas, Samuel

    2015-01-01

    This paper discusses findings from a research study designed to investigate calculus instructors' perceptions of approximation as a central concept and possible unifying thread of the first-year calculus. The study also examines the role approximation plays in participants' self-reported instructional practices. A survey was administered to 279…

  2. Thirty Years of Cloud Cover Patterns from Satellite Data: Fog in California's Central Valley and Coast

    NASA Astrophysics Data System (ADS)

    Waller, E.; Baldocchi, D. D.

    2012-12-01

    In an effort to assess long term trends in winter fog in the Central Valley of California, custom maps of daily cloud cover from an approximately 30 year record of AVHRR (1981-1999) and MODIS (2000-2012) satellite data were generated. Spatial rules were then used to differentiate between fog and general cloud cover. Differences among the sensors (e.g., spectral content, spatial resolution, overpass time) presented problems of consistency, but concurrent climate station data were used to resolve systematic differences in products, and to confirm long term trends. The frequency and extent of Central Valley ("Tule") fog appear to have some periodic oscillation, but also appear to be on the decline, especially in the Sacramento Valley and in the "shoulder" months of November and February. These results may have strong implications for growers of fruit and nut trees in the Central Valley dependent on winter chill hours that are augmented by the foggy daytime conditions. Conclusions about long term trends in fog are limited to daytime patterns, as results are primarily derived from reflectance-based products. Similar analyses of daytime cloud cover are performed on other areas of concern, such as the coastal fog belt of California. Large area and long term patterns here appear to have periodic oscillation similar to that for the Central Valley. However, the relatively coarse spatial resolution of the AVHRR LTDR (Long Term Data Record) data (~5-km) may be limiting for fine-scale analysis of trends.

  3. Effects of a Finger Tapping Fatiguing Task on M1-Intracortical Inhibition and Central Drive to the Muscle.

    PubMed

    Madrid, Antonio; Madinabeitia-Mancebo, Elena; Cudeiro, Javier; Arias, Pablo

    2018-06-19

    The central drive to the muscle reduces when muscle force wanes during sustained MVC, and this is generally considered the neurophysiological footprint of central fatigue. The question is if force loss and the failure of central drive to the muscle are responsible mechanisms of fatigue induced by un-resisted repetitive movements. In various experimental blocks, we validated a 3D-printed hand-fixation system permitting the execution of finger-tapping and maximal voluntary contractions (MVC). Subsequently, we checked the suitability of the system to test the level of central drive to the muscle and developed an algorithm to test it at the MVC force plateau. Our main results show that the maximum rate of finger-tapping dropped at 30 s, while the excitability of inhibitory M1-intracortical circuits and corticospinal excitability increased (all by approximately 15%). Furthermore, values obtained immediately after finger-tapping showed that MVC force and the level of central drive to the muscle remained unchanged. Our data suggest that force and central drive to the muscle are not determinants of fatigue induced by short-lasting un-resisted repetitive finger movements, even in the presence of increased inhibition of the motor cortex. According to literature, this profile might be different in longer-lasting, more complex and/or resisted repetitive movements.

  4. Collection development at the NOAA Central Library

    NASA Technical Reports Server (NTRS)

    Quillen, Steve R.

    1994-01-01

    The National Oceanic and Atmospheric Administration (NOAA) Central Library collection, approximately one million volumes, incorporates the holdings of its predecessor agencies. Within the library, the collections are filed separately, based on their source and/or classification schemes. The NOAA Central Library provides a variety of services to users, ranging from quick reference and interlibrary loan to in-depth research and online data bases.

  5. The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysis.

    PubMed

    Valstad, Mathias; Alvares, Gail A; Egknud, Maiken; Matziorinis, Anna Maria; Andreassen, Ole A; Westlye, Lars T; Quintana, Daniel S

    2017-07-01

    There is growing interest in the role of the oxytocin system in social cognition and behavior. Peripheral oxytocin concentrations are regularly used to approximate central concentrations in psychiatric research, however, the validity of this approach is unclear. Here we conducted a pre-registered systematic search and meta-analysis of correlations between central and peripheral oxytocin concentrations. A search of databases yielded 17 eligible studies, resulting in a total sample size of 516 participants and subjects. Overall, a positive association between central and peripheral oxytocin concentrations was revealed [r=0.29, 95% CI (0.14, 0.42), p<0.0001]. This association was moderated by experimental context [Q b (4), p=0.003]. While no association was observed under basal conditions (r=0.08, p=0.31), significant associations were observed after intranasal oxytocin administration (r=0.66, p<0.0001), and after experimentally induced stress (r=0.49, p=0.001). These results indicate a coordination of central and peripheral oxytocin release after stress and after intranasal administration. Although popular, the approach of using peripheral oxytocin levels to approximate central levels under basal conditions is not supported by the present results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Locus ceruleus control of state-dependent gene expression.

    PubMed

    Cirelli, Chiara; Tononi, Giulio

    2004-06-09

    Wakefulness and sleep are accompanied by changes in behavior and neural activity, as well as by the upregulation of different functional categories of genes. However, the mechanisms responsible for such state-dependent changes in gene expression are unknown. Here we investigate to what extent state-dependent changes in gene expression depend on the central noradrenergic (NA) system, which is active in wakefulness and reduces its firing during sleep. We measured the levels of approximately 5000 transcripts expressed in the cerebral cortex of control rats and in rats pretreated with DSP-4 [N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine], a neurotoxin that removes the noradrenergic innervation of the cortex. We found that NA depletion reduces the expression of approximately 20% of known wakefulness-related transcripts. Most of these transcripts are involved in synaptic plasticity and in the cellular response to stress. In contrast, NA depletion increased the expression of the sleep-related gene encoding the translation elongation factor 2. These results indicate that the activity of the central NA system during wakefulness modulates neuronal transcription to favor synaptic potentiation and counteract cellular stress, whereas its inactivity during sleep may play a permissive role to enhance brain protein synthesis.

  7. [Electromagnetic radiation of non-thermal intensity and short exposition as a sub-threshold irritant for the central nervous system].

    PubMed

    Luk'ianova, S N

    2013-01-01

    This work represents generalization and the analysis of the long-term own materials characterizing reaction of the brain on electromagnetic radiation of low intensity (energy flow density in the continuous regime or in the impulse approximately 500 microW/sm2) and a short exposition (approximately 30 min). A set of the experimental results received on separate neurons, formations and brain as a whole give an idea about the reaction of the central nervous system to the studied influence. Comparison of these data with the corresponding responses to the known incentives (light, sound, electric current) testifies to the electromagnetic radiation of low energy flow density and a short exposition as a sub-threshold irritant for the central nervous system.

  8. An explicit mixed numerical method for mesoscale model

    NASA Technical Reports Server (NTRS)

    Hsu, H.-M.

    1981-01-01

    A mixed numerical method has been developed for mesoscale models. The technique consists of a forward difference scheme for time tendency terms, an upstream scheme for advective terms, and a central scheme for the other terms in a physical system. It is shown that the mixed method is conditionally stable and highly accurate for approximating the system of either shallow-water equations in one dimension or primitive equations in three dimensions. Since the technique is explicit and two time level, it conserves computer and programming resources.

  9. The Acute Phase Response and Soman-Induced Status Epilepticus: Temporal, Regional and Cellular Changes in Rat Brain Cytokine Concentrations

    DTIC Science & Technology

    2010-07-22

    definite trend was observed, with an approximate 3-fold increase over vehicle control values. Significant IL-6 concentra- tion increases were observed in...differences occurred. How- ever, a strong increasing trend is apparent in both the mRNA (TNF-α and IL-6) and protein data (IL-1β) that is consistent with the...CNS pathologies. Trends Neurosci 1996, 19:409-410. 17. Wang CX, Shuaib A: Involvement of inflammatory cytokines in central nervous system injury

  10. Applying the Explicit Time Central Difference Method for Numerical Simulation of the Dynamic Behavior of Elastoplastic Flexible Reinforced Plates

    NASA Astrophysics Data System (ADS)

    Yankovskii, A. P.

    2017-12-01

    Based on a stepwise algorithm involving central finite differences for the approximation in time, a mathematical model is developed for elastoplastic deformation of cross-reinforced plates with isotropically hardening materials of components of the composition. The model allows obtaining the solution of elastoplastic problems at discrete points in time by an explicit scheme. The initial boundary value problem of the dynamic behavior of flexible plates reinforced in their own plane is formulated in the von Kármán approximation with allowance for their weakened resistance to the transverse shear. With a common approach, the resolving equations corresponding to two variants of the Timoshenko theory are obtained. An explicit "cross" scheme for numerical integration of the posed initial boundary value problem has been constructed. The scheme is consistent with the incremental algorithm used for simulating the elastoplastic behavior of a reinforced medium. Calculations of the dynamic behavior have been performed for elastoplastic cylindrical bending of differently reinforced fiberglass rectangular elongated plates. It is shown that the reinforcement structure significantly affects their elastoplastic dynamic behavior. It has been found that the classical theory of plates is as a rule unacceptable for carrying out the required calculations (except for very thin plates), and the first version of the Timoshenko theory yields reasonable results only in cases of relatively thin constructions reinforced by lowmodulus fibers. Proceeding from the results of the work, it is recommended to use the second variant of the Timoshenko theory (as a more accurate one) for calculations of the elastoplastic behavior of reinforced plates.

  11. Population-specific variation in haplotype composition and heterozygosity at the POLB locus.

    PubMed

    Yamtich, Jennifer; Speed, William C; Straka, Eva; Kidd, Judith R; Sweasy, Joann B; Kidd, Kenneth K

    2009-05-01

    DNA polymerase beta plays a central role in base excision repair (BER), which removes large numbers of endogenous DNA lesions from each cell on a daily basis. Little is currently known about germline polymorphisms within the POLB locus, making it difficult to study the association of variants at this locus with human diseases such as cancer. Yet, approximately thirty percent of human tumor types show variants of DNA polymerase beta. We have assessed the global frequency distributions of coding and common non-coding SNPs in and flanking the POLB gene for a total of 14 sites typed in approximately 2400 individuals from anthropologically defined human populations worldwide. We have found a marked difference between haplotype frequencies in African populations and in non-African populations.

  12. BUCKO- A BUCKLING ANALYSIS FOR RECTANGULAR PLATES WITH CENTRALLY LOCATED CUTOUTS

    NASA Technical Reports Server (NTRS)

    Nemeth, M. P.

    1994-01-01

    BUCKO is a computer program developed to predict the buckling load of a rectangular compression-loaded orthotropic plate with a centrally located cutout. The plate is assumed to be a balanced, symmetric laminate of uniform thickness. The cutout shape can be elliptical, circular, rectangular, or square. The BUCKO package includes sample data that demonstrates the essence of the program and its ease of usage. BUCKO uses an approximate one-dimensional formulation of the classical two-dimensional buckling problem following the Kantorovich method. The boundary conditions are considered to be simply supported unloaded edges and either clamped or simply supported loaded edges. The plate is loaded in uniaxial compression by either uniformly displacing or uniformly stressing two opposite edges of the plate. The BUCKO analysis consists of two parts: calculation of the inplane stress distribution prior to buckling, and calculation of the plate axial load and displacement at buckling. User input includes plate planform and cutout geometry, plate membrane and bending stiffnesses, finite difference parameters, boundary condition data, and loading data. Results generated by BUCKO are the prebuckling strain energy, inplane stress resultants, buckling mode shape, critical end shortening, and average axial and transverse strains at buckling. BUCKO is written in FORTRAN V for batch execution and has been implemented on a CDC CYBER 170 series computer operating under NOS with a central memory requirement of approximately 343K of 60 bit words. This program was developed in 1984 and was last updated in 1990.

  13. Fundamental gaps with approximate density functionals: The derivative discontinuity revealed from ensemble considerations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kraisler, Eli; Kronik, Leeor

    2014-05-14

    The fundamental gap is a central quantity in the electronic structure of matter. Unfortunately, the fundamental gap is not generally equal to the Kohn-Sham gap of density functional theory (DFT), even in principle. The two gaps differ precisely by the derivative discontinuity, namely, an abrupt change in slope of the exchange-correlation energy as a function of electron number, expected across an integer-electron point. Popular approximate functionals are thought to be devoid of a derivative discontinuity, strongly compromising their performance for prediction of spectroscopic properties. Here we show that, in fact, all exchange-correlation functionals possess a derivative discontinuity, which arises naturallymore » from the application of ensemble considerations within DFT, without any empiricism. This derivative discontinuity can be expressed in closed form using only quantities obtained in the course of a standard DFT calculation of the neutral system. For small, finite systems, addition of this derivative discontinuity indeed results in a greatly improved prediction for the fundamental gap, even when based on the most simple approximate exchange-correlation density functional – the local density approximation (LDA). For solids, the same scheme is exact in principle, but when applied to LDA it results in a vanishing derivative discontinuity correction. This failure is shown to be directly related to the failure of LDA in predicting fundamental gaps from total energy differences in extended systems.« less

  14. The probability of misassociation between neighboring targets

    NASA Astrophysics Data System (ADS)

    Areta, Javier A.; Bar-Shalom, Yaakov; Rothrock, Ronald

    2008-04-01

    This paper presents procedures to calculate the probability that the measurement originating from an extraneous target will be (mis)associated with a target of interest for the cases of Nearest Neighbor and Global association. It is shown that these misassociation probabilities depend, under certain assumptions, on a particular - covariance weighted - norm of the difference between the targets' predicted measurements. For the Nearest Neighbor association, the exact solution, obtained for the case of equal innovation covariances, is based on a noncentral chi-square distribution. An approximate solution is also presented for the case of unequal innovation covariances. For the Global case an approximation is presented for the case of "similar" innovation covariances. In the general case of unequal innovation covariances where this approximation fails, an exact method based on the inversion of the characteristic function is presented. The theoretical results, confirmed by Monte Carlo simulations, quantify the benefit of Global vs. Nearest Neighbor association. These results are applied to problems of single sensor as well as centralized fusion architecture multiple sensor tracking.

  15. Ground-state splitting of ultrashallow thermal donors with negative central-cell corrections in silicon

    NASA Astrophysics Data System (ADS)

    Hara, Akito; Awano, Teruyoshi

    2017-06-01

    Ultrashallow thermal donors (USTDs), which consist of light element impurities such as carbon, hydrogen, and oxygen, have been found in Czochralski silicon (CZ Si) crystals. To the best of our knowledge, these are the shallowest hydrogen-like donors with negative central-cell corrections in Si. We observed the ground-state splitting of USTDs by far-infrared optical absorption at different temperatures. The upper ground-state levels are approximately 4 meV higher than the ground-state levels. This energy level splitting is also consistent with that obtained by thermal excitation from the ground state to the upper ground state. This is direct evidence that the wave function of the USTD ground state is made up of a linear combination of conduction band minimums.

  16. High order filtering methods for approximating hyberbolic systems of conservation laws

    NASA Technical Reports Server (NTRS)

    Lafon, F.; Osher, S.

    1990-01-01

    In the computation of discontinuous solutions of hyperbolic systems of conservation laws, the recently developed essentially non-oscillatory (ENO) schemes appear to be very useful. However, they are computationally costly compared to simple central difference methods. A filtering method which is developed uses simple central differencing of arbitrarily high order accuracy, except when a novel local test indicates the development of spurious oscillations. At these points, the full ENO apparatus is used, maintaining the high order of accuracy, but removing spurious oscillations. Numerical results indicate the success of the method. High order of accuracy was obtained in regions of smooth flow without spurious oscillations for a wide range of problems and a significant speed up of generally a factor of almost three over the full ENO method.

  17. The interstellar medium in the starburst regions of NGC 253 and NGC 3256

    NASA Astrophysics Data System (ADS)

    Carral, P.; Hollenbach, D. J.; Lord, S. D.; Colgan, S. W. J.; Haas, Michael R.; Rubin, R. H.; Erickson, E. F.

    1994-03-01

    We discuss observations of the (C II) 158 micrometers, (O I) 63 micrometers, (Si II) 35 micrometers, (O III) 52,88 micrometers, and (S III) 33 micrometers fine-structure transitions toward the central 45 seconds of the starburst galaxies NGC 253 and NGC 3256. The (C II) and (O I) emission probably originates in photodissociated gas at the surfaces of molecular clouds, although a small (less than or approximately 30%) contribution to the (C II) flux from H II regions cannot be ruled out. The (O III) and (S III) lines originate in H II regions and the (Si II) flux is best explained as originating in H II regions with some contribution from photodissociation regions (PDRs). The gas phase silicon abundance is nearly solar in NGC 253, which we interpret as evidence for grain destruction in the starburst region. We find that the photodissociated atomic gas has densities approximately 104/cu cm and temperature 200-300 K. About 2% of the gas is in this phase. The thermal gas pressure in the PDRs, P(PDR)/k approximately 1-3 x 106 K/cu cm, might represent the 'typical' interstellar gas pressure in starburst systems. The Far Ultraviolet (FUV) radiation fields illuminating the clouds are 103-104 stronger than the local Galactic FUV field and come from the contribution of many closely packed O and B stars. For the central 250 pc of NGC 253, we find that the H II gas has an average density ne is approximately 400/cu cm. This corresponds to a thermal pressure P(H II)/k approximately 7 x 106 K/cu cm which is approximately P(PDR)/k, suggesting that the ionized gas is in pressure equilibrium with the photodissociated gas at the surfaces of molecular clouds. The H II gas fills a significant fraction, approximately 0.01-0.3, of the volume between the clouds. The effective temperature of the ionizing stars in NGC 253 is greater than or approximately 34,500 K; 2 x 105 O7.5 stars would produce the observed Lyman continuum photon luminosity. The average separation between the stars is approximately 3 pc. Applying the simple model for the interstellar medium in galactic nuclei of Wolfire, Tielens, & Hollenbach (1990), we find the molecular gas in the central regions of NGC 253 and NGC 3256 to be distributed in a large number (5 x 103 to 5 x 105) of small (0.5-2 pc), dense (approximately 104/cu cm) clouds (or alternatively 'thin-flattened' structures) with volume filling factors 10-3 to 10-2, very different from the local Interstellar Medium (ISM) of the Galaxy. We suggest a self-consistent scenario for the ISM in NGC 253 in which clouds and H II gas are in pressure balance with a supernova-shocked, hot 1-3 x 106 K, low-density (approximately 104/cu cm), all pervasive medium. A feedback mechanism may be indicated in which the pressure generated by the supernovae compresses the molecular clouds and triggers further massive star formation. The similarity of ISM parameters deduced for NGC 253, NGC 3256, and M82 (Lord et al. 1993) suggests that the ISM properties are independent of the luminosity of the starburst or the triggering mechanism, but are rather endemic to starburst systems. The starburst in NGC 3256 appears to be a scaled-up version of the NGC 253 and M82 starbursts.

  18. Consonants, vowels and tones across Vietnamese dialects.

    PubMed

    PhȦm, Ben; McLeod, Sharynne

    2016-04-01

    Vietnamese is spoken by over 89 million people in Vietnam and it is one of the most commonly spoken languages other than English in the US, Canada and Australia. This study defines between one and nine different dialects of Vietnamese spoken in Vietnam. In Vietnamese schools, children learn Standard Vietnamese which is based on the northern dialect; however, if they live in other regions they may speak a different dialect at home. This paper describes the differences between the consonants, semivowels, vowels, diphthongs and tones for four dialects: Standard, northern, central and southern Vietnamese. The number and type of initial consonants differs per dialect (i.e. Standard = 23, northern = 20, central = 23, southern = 21). For example, the letter "r" is pronounced in the Standard and central dialects as the retroflex /ʐ/, northern dialect as the voiced alveolar fricative /z/ or the trilled /r/ and in the southern dialect as the voiced velar fricative /ɣ/. Additionally, the letter "v" is pronounced in the Standard, northern and central dialects as the voiced bilabial fricative /v/, the southern dialect as the voiced palatal approximant /j/ and in the lower northern dialect (Ninh Binh) as the voiceless bilabial fricative /f/. Similarly, the number of final consonants differs per dialect (i.e. Standard = 6, northern = 10, central = 10, southern = 8). Finally, the number and type of tones differs per dialect (i.e. Standard = 6, northern = 6, central = 5, southern = 5). Understanding differences between Vietnamese dialects is important so that speech-language pathologists and educators provide appropriate services to people who speak Vietnamese.

  19. Trivial constraints on orbital-free kinetic energy density functionals

    NASA Astrophysics Data System (ADS)

    Luo, Kai; Trickey, S. B.

    2018-03-01

    Approximate kinetic energy density functionals (KEDFs) are central to orbital-free density functional theory. Limitations on the spatial derivative dependencies of KEDFs have been claimed from differential virial theorems. We identify a central defect in the argument: the relationships are not true for an arbitrary density but hold only for the minimizing density and corresponding chemical potential. Contrary to the claims therefore, the relationships are not constraints and provide no independent information about the spatial derivative dependencies of approximate KEDFs. A simple argument also shows that validity for arbitrary v-representable densities is not restored by appeal to the density-potential bijection.

  20. The D-dimensional non-relativistic particle in the Scarf Trigonometry plus Non-Central Rosen-Morse Potentials

    NASA Astrophysics Data System (ADS)

    Deta, U. A.; Lestari, N. A.; Yantidewi, M.; Suparmi, A.; Cari, C.

    2018-03-01

    The D-Dimensional Non-Relativistic Particle Properties in the Scarf Trigonometry plus Non-Central Rosen-Morse Potentials was investigated using an analytical method. The bound state energy is given approximately in the closed form. The approximate wave function for arbitrary l-state in D-dimensions are expressed in the form of generalised Jacobi Polynomials. The energy spectra of the particle are increased when the dimensions are higher. The relationship between the orbital number in each dimension is recursive. The special case in 3 dimensions is given to the ground state.

  1. Rice University observations of the galactic center

    NASA Technical Reports Server (NTRS)

    Meegan, C. A.

    1978-01-01

    The most sensitive of the four balloon fight observations of the galactic center made by Rice University was conducted in 1974 from Rio Cuarto, Argentina at a float altitude of 4 mbar. The count rate spectrum of the observed background and the energy spectrum of the galactic center region are discussed. The detector used consists of a 6 inch Nal(T 1ambda) central detector collimated to approximately 15 deg FWHM by a Nal(T lamdba) anticoincidence shield. The shield in at least two interaction mean free paths thick at all gamma ray energies. The instrumental resolution is approximately 11% FWHM at 662 keV. Pulses from the central detector are analyzed by two 256 channel PHA's covering the energy range approximately 20 keV to approximately 12 MeV. The detector is equatorially mounted and pointed by command from the ground. Observations are made by measuring source and background alternately for 10 minute periods. Background is measured by rotating the detector 180 deg about the azimuthal axis.

  2. Economic Development Through Biomass Systems Integration in Central Florida: Final Report; May 5, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stricker, J. A.; Smith, W. H.

    Reclaimed phosphate mined land in central Florida has been identified as an area with potential for growing biomass crops. Approximately 73,000 acres of land could be available for production. Additional research is needed to define the possibilities.

  3. High baryon and energy densities achievable in heavy-ion collisions at √{sN N}=39 GeV

    NASA Astrophysics Data System (ADS)

    Ivanov, Yu. B.; Soldatov, A. A.

    2018-02-01

    Baryon and energy densities, which are reached in central Au+Au collisions at collision energy of √{sN N}= 39 GeV, are estimated within the model of three-fluid dynamics. It is shown that the initial thermalized mean proper baryon and energy densities in a sizable central region approximately are nB/n0≈ 10 and ɛ ≈ 40 GeV/fm3, respectively. The study indicates that the deconfinement transition at the stage of interpenetration of colliding nuclei makes the system quite opaque. The final fragmentation regions in these collisions are formed not only by primordial fragmentation fireballs, i.e., the baryon-rich matter passed through the interaction region (containing approximately 30% of the total baryon charge), but also by the baryon-rich regions of the central fireball pushed out to peripheral rapidities by the subsequent almost one-dimensional expansion of the central fireball along the beam direction.

  4. Axonal Elongation into Peripheral Nervous System ``Bridges'' after Central Nervous System Injury in Adult Rats

    NASA Astrophysics Data System (ADS)

    David, Samuel; Aguayo, Albert J.

    1981-11-01

    The origin, termination, and length of axonal growth after focal central nervous system injury was examined in adult rats by means of a new experimental model. When peripheral nerve segments were used as ``bridges'' between the medulla and spinal cord, axons from neurons at both these levels grew approximately 30 millimeters. The regenerative potential of these central neurons seems to be expressed when the central nervous system glial environment is changed to that of the peripheral nervous system.

  5. Parallel Computing of Upwelling in a Rotating Stratified Flow

    NASA Astrophysics Data System (ADS)

    Cui, A.; Street, R. L.

    1997-11-01

    A code for the three-dimensional, unsteady, incompressible, and turbulent flow has been implemented on the IBM SP2, using message passing. The effects of rotation and variable density are included. A finite volume method is used to discretize the Navier-Stokes equations in general curvilinear coordinates on a non-staggered grid. All the spatial derivatives are approximated using second-order central differences with the exception of the convection terms, which are handled with special upwind-difference schemes. The semi-implicit, second-order accurate, time-advancement scheme employs the Adams-Bashforth method for the explicit terms and Crank-Nicolson for the implicit terms. A multigrid method, with the four-color ZEBRA as smoother, is used to solve the Poisson equation for pressure, while the momentum equations are solved with an approximate factorization technique. The code was successfully validated for a variety test cases. Simulations of a laboratory model of coastal upwelling in a rotating annulus are in progress and will be presented.

  6. A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity

    PubMed Central

    Brown, William R. A.; Liti, Gianni; Rosa, Carlos; James, Steve; Roberts, Ian; Robert, Vincent; Jolly, Neil; Tang, Wen; Baumann, Peter; Green, Carter; Schlegel, Kristina; Young, Jonathan; Hirchaud, Fabienne; Leek, Spencer; Thomas, Geraint; Blomberg, Anders; Warringer, Jonas

    2011-01-01

    The fission yeast Schizosaccharomyces pombe has been widely used to study eukaryotic cell biology, but almost all of this work has used derivatives of a single strain. We have studied 81 independent natural isolates and 3 designated laboratory strains of Schizosaccharomyces pombe. Schizosaccharomyces pombe varies significantly in size but shows only limited variation in proliferation in different environments compared with Saccharomyces cerevisiae. Nucleotide diversity, π, at a near neutral site, the central core of the centromere of chromosome II is approximately 0.7%. Approximately 20% of the isolates showed karyotypic rearrangements as detected by pulsed field gel electrophoresis and filter hybridization analysis. One translocation, found in 6 different isolates, including the type strain, has a geographically widespread distribution and a unique haplotype and may be a marker of an incipient speciation event. All of the other translocations are unique. Exploitation of this karyotypic diversity may cast new light on both the biology of telomeres and centromeres and on isolating mechanisms in single-celled eukaryotes. PMID:22384373

  7. Effect of Age and Glaucoma on the Detection of Darks and Lights

    PubMed Central

    Zhao, Linxi; Sendek, Caroline; Davoodnia, Vandad; Lashgari, Reza; Dul, Mitchell W.; Zaidi, Qasim; Alonso, Jose-Manuel

    2015-01-01

    Purpose We have shown previously that normal observers detect dark targets faster and more accurately than light targets, when presented in noisy backgrounds. We investigated how these differences in detection time and accuracy are affected by age and ganglion cell pathology associated with glaucoma. Methods We asked 21 glaucoma patients, 21 age-similar controls, and 5 young control observers to report as fast as possible the number of 1 to 3 light or dark targets. The targets were positioned at random in a binary noise background, within the central 30° of the visual field. Results We replicate previous findings that darks are detected faster and more accurately than lights. We extend these findings by demonstrating that differences in detection of darks and lights are found reliably across different ages and in observers with glaucoma. We show that differences in detection time increase at a rate of approximately 55 msec/dB at early stages of glaucoma and then remain constant at later stages at approximately 800 msec. In normal subjects, differences in detection time increase with age at a rate of approximately 8 msec/y. We also demonstrate that the accuracy to detect lights and darks is significantly correlated with the severity of glaucoma and that the mean detection time is significantly longer for subjects with glaucoma than age-similar controls. Conclusions We conclude that differences in detection of darks and lights can be demonstrated over a wide range of ages, and asymmetries in dark/light detection increase with age and early stages of glaucoma. PMID:26513506

  8. Effect of Age and Glaucoma on the Detection of Darks and Lights.

    PubMed

    Zhao, Linxi; Sendek, Caroline; Davoodnia, Vandad; Lashgari, Reza; Dul, Mitchell W; Zaidi, Qasim; Alonso, Jose-Manuel

    2015-10-01

    We have shown previously that normal observers detect dark targets faster and more accurately than light targets, when presented in noisy backgrounds. We investigated how these differences in detection time and accuracy are affected by age and ganglion cell pathology associated with glaucoma. We asked 21 glaucoma patients, 21 age-similar controls, and 5 young control observers to report as fast as possible the number of 1 to 3 light or dark targets. The targets were positioned at random in a binary noise background, within the central 30° of the visual field. We replicate previous findings that darks are detected faster and more accurately than lights. We extend these findings by demonstrating that differences in detection of darks and lights are found reliably across different ages and in observers with glaucoma. We show that differences in detection time increase at a rate of approximately 55 msec/dB at early stages of glaucoma and then remain constant at later stages at approximately 800 msec. In normal subjects, differences in detection time increase with age at a rate of approximately 8 msec/y. We also demonstrate that the accuracy to detect lights and darks is significantly correlated with the severity of glaucoma and that the mean detection time is significantly longer for subjects with glaucoma than age-similar controls. We conclude that differences in detection of darks and lights can be demonstrated over a wide range of ages, and asymmetries in dark/light detection increase with age and early stages of glaucoma.

  9. Spatiotemporal mapping of sex differences during attentional processing.

    PubMed

    Neuhaus, Andres H; Opgen-Rhein, Carolin; Urbanek, Carsten; Gross, Melanie; Hahn, Eric; Ta, Thi Minh Tam; Koehler, Simone; Dettling, Michael

    2009-09-01

    Functional neuroimaging studies have increasingly aimed at approximating neural substrates of human cognitive sex differences elicited by visuospatial challenge. It has been suggested that females and males use different behaviorally relevant neurocognitive strategies. In females, greater right prefrontal cortex activation has been found in several studies. The spatiotemporal dynamics of neural events associated with these sex differences is still unclear. We studied 22 female and 22 male participants matched for age, education, and nicotine with 29-channel-electroencephalogram recorded under a visual selective attention paradigm, the Attention Network Test. Visual event-related potentials (ERP) were topographically analyzed and neuroelectric sources were estimated. In absence of behavioral differences, ERP analysis revealed a novel frontal-occipital second peak of visual N100 that was significantly increased in females relative to males. Further, in females exclusively, a corresponding central ERP component at around 220 ms was found; here, a strong correlation between stimulus salience and sex difference of the central ERP component amplitude was observed. Subsequent source analysis revealed increased cortical current densities in right rostral prefrontal (BA 10) and occipital cortex (BA 19) in female subjects. This is the first study to report on a tripartite association between sex differences in ERPs, visual stimulus salience, and right prefrontal cortex activation during attentional processing. 2009 Wiley-Liss, Inc.

  10. 75 FR 56161 - Stillwater Central Railroad, Inc.-Trackage Rights Exemption-BNSF Railway Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... Railroad, Inc.--Trackage Rights Exemption-- BNSF Railway Company Pursuant to a written trackage rights agreement (Trackage Agreement) dated December 29, 2004, BNSF Railway Company (BNSF) granted approximately 5.5 miles of incidental overhead trackage rights to Stillwater Central Railroad, Inc. (SLWC...

  11. Total Variation Diminishing (TVD) schemes of uniform accuracy

    NASA Technical Reports Server (NTRS)

    Hartwich, PETER-M.; Hsu, Chung-Hao; Liu, C. H.

    1988-01-01

    Explicit second-order accurate finite-difference schemes for the approximation of hyperbolic conservation laws are presented. These schemes are nonlinear even for the constant coefficient case. They are based on first-order upwind schemes. Their accuracy is enhanced by locally replacing the first-order one-sided differences with either second-order one-sided differences or central differences or a blend thereof. The appropriate local difference stencils are selected such that they give TVD schemes of uniform second-order accuracy in the scalar, or linear systems, case. Like conventional TVD schemes, the new schemes avoid a Gibbs phenomenon at discontinuities of the solution, but they do not switch back to first-order accuracy, in the sense of truncation error, at extrema of the solution. The performance of the new schemes is demonstrated in several numerical tests.

  12. Radial Surface Density Profiles of Gas and Dust in the Debris Disk Around 49 Ceti

    NASA Technical Reports Server (NTRS)

    Hughes, A. Meredith; Lieman-Sifry, Jesse; Flaherty, Kevin M.; Daley, Cail M.; Roberge, Aki; Kospal, Agnes; Moor, Attila; Kamp, Inga; Wilner, David J.; Andrews, Sean M.; hide

    2017-01-01

    We present approximately 0".4 resolution images of CO(3-2) and associated continuum emission from the gas-bearing debris disk around the nearby A star 49 Ceti, observed with the Atacama Large Millimeter/Submillimeter Array (ALMA). We analyze the ALMA visibilities in tandem with the broadband spectral energy distribution to measure the radial surface density profiles of dust and gas emission from the system. The dust surface density decreases with radius between approximately 100 and 310 au, with a marginally significant enhancement of surface density at a radius of approximately 110 au. The SED requires an inner disk of small grains in addition to the outer disk of larger grains resolved by ALMA. The gas disk exhibits a surface density profile that increases with radius, contrary to most previous spatially resolved observations of circumstellar gas disks. While approximately 80% of the CO flux is well described by an axisymmetric power-law disk in Keplerian rotation about the central star, residuals at approximately 20% of the peak flux exhibit a departure from axisymmetry suggestive of spiral arms or a warp in the gas disk. The radial extent of the gas disk (approx. 220 au) is smaller than that of the dust disk (approx. 300 au), consistent with recent observations of other gasbearing debris disks. While there are so far only three broad debris disks with well characterized radial dust profiles at millimeter wavelengths, 49 Ceti's disk shows a markedly different structure from two radially resolved gas-poor debris disks, implying that the physical processes generating and sculpting the gas and dust are fundamentally different.

  13. Transverse bacterial migration induced by chemotaxis in a packed column with structured physical heterogeneity.

    PubMed

    Wang, Meng; Ford, Roseanne M

    2009-08-01

    The significance of chemotaxis in directing bacterial migration toward contaminants in natural porous media was investigated under groundwater flow conditions. A laboratory-scale column, with a coarse-grained sand core surrounded by a fine-grained annulus, was used to simulate natural aquifers with strata of different hydraulic conductivities. A chemoattractant source was placed along the central axis of the column to model contaminants trapped in the heterogeneous subsurface. Chemotactic bacterial strains, Escherichia coli HCB1 and Pseudomonas putida F1, introduced into the column by a pulse injection, were found to alter their transport behaviors under the influence of the attractant chemical emanating from the central source. For E. coil HCB1, approximately 18% more of the total population relative to the control without attractant exited the column from the coarse sand layer due to the chemotactic effects of alpha-methylaspartate under an average fluid velocity of 5.1 m/d. Although P. putida F1 demonstrated no observable changes in migration pathways with the model contaminant acetate under the same flow rate, when the flow rate was reduced to 1.9 m/d, approximately 6-10% of the population relative to the control migrated from the fine sand layer toward attractant into the coarse sand layer. Microbial transport properties were further quantified by a mathematical model to examine the significance of bacterial motility and chemotaxis under different hydrodynamic conditions, which suggested important considerations for strain selection and practical operation of bioremediation schemes.

  14. 2001 Annual Tropical Cyclone Report

    DTIC Science & Technology

    2001-12-01

    northwest passing over the central Philippine Islands then into the South China Sea before dissipating off western Luzon on 22 February. (3) Reuters...hours prior to making landfall in Southern Taiwan. (2) Taiwan’s Central Weather Bureau (CWB) indicated that rainfall rates in the Pingtung County...1) Attained peak intensity of 100 kts at approximately 1800Z 29 July after making landfall. (2) The Taipei Central News Agency reported 72 fatalities

  15. On the Total Variation of High-Order Semi-Discrete Central Schemes for Conservation Laws

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron

    2004-01-01

    We discuss a new fifth-order, semi-discrete, central-upwind scheme for solving one-dimensional systems of conservation laws. This scheme combines a fifth-order WENO reconstruction, a semi-discrete central-upwind numerical flux, and a strong stability preserving Runge-Kutta method. We test our method with various examples, and give particular attention to the evolution of the total variation of the approximations.

  16. High-Order Central WENO Schemes for 1D Hamilton-Jacobi Equations

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron; Biegel, Bryan A. (Technical Monitor)

    2002-01-01

    In this paper we derive fully-discrete Central WENO (CWENO) schemes for approximating solutions of one dimensional Hamilton-Jacobi (HJ) equations, which combine our previous works. We introduce third and fifth-order accurate schemes, which are the first central schemes for the HJ equations of order higher than two. The core ingredient is the derivation of our schemes is a high-order CWENO reconstructions in space.

  17. Chapter 1: Central Arizona Highlands

    Treesearch

    Peter F. Ffolliott

    1999-01-01

    The Central Arizona Highlands are a distinct biogeographic, climatic, and physiographic province that forms a diverse ecotone between the larger Colorado Plateau to the north and the Sonoran Desert ecoregions to the south (figure 1). The Highlands coincide approximately with the Arizona Transition Zone identified by ecologists, geologists and others. This region is one...

  18. 27 CFR 9.79 - Lake Michigan Shore.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Starting at the most northern point, the intersection the Kalamazoo River with Lake Michigan. (2) Then southeast along the winding course of the Kalamazoo River for approximately 35 miles until it intersects the Penn Central railroad line just south of the City of Otsego. (3) Then south along the Penn Central...

  19. DIGITAL GEOLOGIC MAP OF SHERMAN QUADRANGLE, NORTH CENTRAL TEXAS (CD-ROM)

    EPA Science Inventory

    This compact disc contains digital data sets of the surficial geology and geologic faults for the 1:250,000-scale Sherman quadrangle, North Central Texas, and can be used to make geologic maps, and determine approximate areas and locations of various geologic units. The source d...

  20. Readability of Questionnaires Assessing Listening Difficulties Associated with (Central) Auditory Processing Disorders

    ERIC Educational Resources Information Center

    Atcherson, Samuel R.; Richburg, Cynthia M.; Zraick, Richard I.; George, Cassandra M.

    2013-01-01

    Purpose: Eight English-language, student- or parent proxy-administered questionnaires for (central) auditory processing disorders, or (C)APD, were analyzed for readability. For student questionnaires, readability levels were checked against the approximate reading grade levels by intended administration age per the questionnaires' developers. For…

  1. Correlation between centrality metrics and their application to the opinion model

    NASA Astrophysics Data System (ADS)

    Li, Cong; Li, Qian; Van Mieghem, Piet; Stanley, H. Eugene; Wang, Huijuan

    2015-03-01

    In recent decades, a number of centrality metrics describing network properties of nodes have been proposed to rank the importance of nodes. In order to understand the correlations between centrality metrics and to approximate a high-complexity centrality metric by a strongly correlated low-complexity metric, we first study the correlation between centrality metrics in terms of their Pearson correlation coefficient and their similarity in ranking of nodes. In addition to considering the widely used centrality metrics, we introduce a new centrality measure, the degree mass. The mth-order degree mass of a node is the sum of the weighted degree of the node and its neighbors no further than m hops away. We find that the betweenness, the closeness, and the components of the principal eigenvector of the adjacency matrix are strongly correlated with the degree, the 1st-order degree mass and the 2nd-order degree mass, respectively, in both network models and real-world networks. We then theoretically prove that the Pearson correlation coefficient between the principal eigenvector and the 2nd-order degree mass is larger than that between the principal eigenvector and a lower order degree mass. Finally, we investigate the effect of the inflexible contrarians selected based on different centrality metrics in helping one opinion to compete with another in the inflexible contrarian opinion (ICO) model. Interestingly, we find that selecting the inflexible contrarians based on the leverage, the betweenness, or the degree is more effective in opinion-competition than using other centrality metrics in all types of networks. This observation is supported by our previous observations, i.e., that there is a strong linear correlation between the degree and the betweenness, as well as a high centrality similarity between the leverage and the degree.

  2. A new species of Alsodes (Anura: Alsodidae) from Altos de Cantillana, central Chile.

    PubMed

    Charrier, Andrés; Correa, Claudio; Castro, Camila; Méndez, Marco A

    2015-02-05

    Based on morphological and molecular evidence (mitochondrial and nuclear sequences) we describe a new species of spiny-chest frog, Alsodes cantillanensis, from central Chile (around 34°S). The type locality, Quebrada Infiernillo, is located in the Coastal Range at approximately 65 km from Santiago (Metropolitan Region), the capital of Chile. The distribution of the new species is included entirely in that of A. nodosus (32-36°S approximately), which was identified as the sister taxon according to molecular phylogenetic analyses. Moreover, both species are sympatric in the type locality. The new species was found in a Nothofagus macrocarpa relict forest potentially threatened by gold mining activities. We identify other threats for its conservation and some biological data needed for understanding the evolution of this species. This discovery reveals the scarce knowledge about biogeography, evolution and ecology of spiny-chest frogs from central Chile. 

  3. Finite element dynamic analysis on CDC STAR-100 computer

    NASA Technical Reports Server (NTRS)

    Noor, A. K.; Lambiotte, J. J., Jr.

    1978-01-01

    Computational algorithms are presented for the finite element dynamic analysis of structures on the CDC STAR-100 computer. The spatial behavior is described using higher-order finite elements. The temporal behavior is approximated by using either the central difference explicit scheme or Newmark's implicit scheme. In each case the analysis is broken up into a number of basic macro-operations. Discussion is focused on the organization of the computation and the mode of storage of different arrays to take advantage of the STAR pipeline capability. The potential of the proposed algorithms is discussed and CPU times are given for performing the different macro-operations for a shell modeled by higher order composite shallow shell elements having 80 degrees of freedom.

  4. Hybrid models for chemical reaction networks: Multiscale theory and application to gene regulatory systems.

    PubMed

    Winkelmann, Stefanie; Schütte, Christof

    2017-09-21

    Well-mixed stochastic chemical kinetics are properly modeled by the chemical master equation (CME) and associated Markov jump processes in molecule number space. If the reactants are present in large amounts, however, corresponding simulations of the stochastic dynamics become computationally expensive and model reductions are demanded. The classical model reduction approach uniformly rescales the overall dynamics to obtain deterministic systems characterized by ordinary differential equations, the well-known mass action reaction rate equations. For systems with multiple scales, there exist hybrid approaches that keep parts of the system discrete while another part is approximated either using Langevin dynamics or deterministically. This paper aims at giving a coherent overview of the different hybrid approaches, focusing on their basic concepts and the relation between them. We derive a novel general description of such hybrid models that allows expressing various forms by one type of equation. We also check in how far the approaches apply to model extensions of the CME for dynamics which do not comply with the central well-mixed condition and require some spatial resolution. A simple but meaningful gene expression system with negative self-regulation is analysed to illustrate the different approximation qualities of some of the hybrid approaches discussed. Especially, we reveal the cause of error in the case of small volume approximations.

  5. Hybrid models for chemical reaction networks: Multiscale theory and application to gene regulatory systems

    NASA Astrophysics Data System (ADS)

    Winkelmann, Stefanie; Schütte, Christof

    2017-09-01

    Well-mixed stochastic chemical kinetics are properly modeled by the chemical master equation (CME) and associated Markov jump processes in molecule number space. If the reactants are present in large amounts, however, corresponding simulations of the stochastic dynamics become computationally expensive and model reductions are demanded. The classical model reduction approach uniformly rescales the overall dynamics to obtain deterministic systems characterized by ordinary differential equations, the well-known mass action reaction rate equations. For systems with multiple scales, there exist hybrid approaches that keep parts of the system discrete while another part is approximated either using Langevin dynamics or deterministically. This paper aims at giving a coherent overview of the different hybrid approaches, focusing on their basic concepts and the relation between them. We derive a novel general description of such hybrid models that allows expressing various forms by one type of equation. We also check in how far the approaches apply to model extensions of the CME for dynamics which do not comply with the central well-mixed condition and require some spatial resolution. A simple but meaningful gene expression system with negative self-regulation is analysed to illustrate the different approximation qualities of some of the hybrid approaches discussed. Especially, we reveal the cause of error in the case of small volume approximations.

  6. Direct Collapse to Supermassive Black Hole Seeds with Radiative Transfer: Isolated Halos

    NASA Astrophysics Data System (ADS)

    Luo, Yang; Ardaneh, Kazem; Shlosman, Isaac; Nagamine, Kentaro; Wise, John H.; Begelman, Mitchell C.

    2018-05-01

    Direct collapse within dark matter haloes is a promising path to form supermassive black hole seeds at high redshifts. The outer part of this collapse remains optically thin. However, the innermost region of the collapse is expected to become optically thick and requires to follow the radiation field in order to understand its evolution. So far, the adiabatic approximation has been used exclusively for this purpose. We apply radiative transfer in the flux-limited diffusion (FLD) approximation to solve the evolution of coupled gas and radiation for isolated haloes. We find that (1) the photosphere forms at 10-6 pc and rapidly expands outwards. (2) A central core forms, with a mass of 1 M⊙, supported by gas pressure gradients and rotation. (3) Growing gas and radiation pressure gradients dissolve it. (4) This process is associated with a strong anisotropic outflow; another core forms nearby and grows rapidly. (5) Typical radiation luminosity emerging from the photosphere is 5 × 1037-5 × 1038 erg s-1, of the order the Eddington luminosity. (6) Two variability time-scales are associated with this process: a long one, which is related to the accretion flow within the central 10-4-10-3 pc, and 0.1 yr, related to radiation diffusion. (7) Adiabatic models evolution differs profoundly from that of the FLD models, by forming a geometrically thick disc. Overall, an adiabatic equation of state is not a good approximation to the advanced stage of direct collapse, because the radiation is capable of escaping due to anisotropy in the optical depth and associated gradients.

  7. Developing a structure-function model for the cryptophyte phycoerythrin 545 using ultrahigh resolution crystallography and ultrafast laser spectroscopy.

    PubMed

    Doust, Alexander B; Marai, Christopher N J; Harrop, Stephen J; Wilk, Krystyna E; Curmi, Paul M G; Scholes, Gregory D

    2004-11-12

    Cryptophyte algae differ from cyanobacteria and red algae in the architecture of their photosynthetic light harvesting systems, even though all three are evolutionarily related. Central to cryptophyte light harvesting is the soluble antenna protein phycoerythrin 545 (PE545). The ultrahigh resolution crystal structure of PE545, isolated from a unicellular cryptophyte Rhodomonas CS24, is reported at both 1.1A and 0.97A resolution, revealing details of the conformation and environments of the chromophores. Absorption, emission and polarized steady state spectroscopy (298K, 77K), as well as ultrafast (20fs time resolution) measurements of population dynamics are reported. Coupled with complementary quantum chemical calculations of electronic transitions of the bilins, these enable assignment of spectral absorption characteristics to each chromophore in the structure. Spectral differences between the tetrapyrrole pigments due to chemical differences between bilins, as well as their binding and interaction with the local protein environment are described. Based on these assignments, and considering customized optical properties such as strong coupling, a model for light harvesting by PE545 is developed which explains the fast, directional harvesting of excitation energy. The excitation energy is funnelled from four peripheral pigments (beta158,beta82) into a central chromophore dimer (beta50/beta61) in approximately 1ps. Those chromophores, in turn, transfer the excitation energy to the red absorbing molecules located at the periphery of the complex in approximately 4ps. A final resonance energy transfer step sensitizes just one of the alpha19 bilins on a time scale of 22ps. Furthermore, it is concluded that binding of PE545 to the thylakoid membrane is not essential for efficient energy transfer to the integral membrane chlorophyll a-containing complexes associated with PS-II.

  8. The scientific goal of the Japanese small astrometric satellite, Small-JASMINE

    NASA Astrophysics Data System (ADS)

    Yano, Taihei; Gouda, Naoteru; Kobayashi, Yukiyasu; Tsujimoto, Takuji; Niwa, Yoshito; Yamada, Yoshiyuki

    2013-02-01

    Small-JASMINE is a small Japanese astrometric satellite, developed mainly at the National Astronomical Observatory of Japan. The target launch date of Small-JASMINE is around 2017. The satellite will be equipped with a telescope with an aperture size of 30 cm and a focal length of approximately 3.9 m. The operational wavelength will be centered on the infrared Hw band, between 1.1 and 1.7 μm, using a HgCdTe detector with 4k × 4k pixels. This will enable us to observe the central regions of our Galaxy and clarify the dynamical structure of the bulge region. A restricted region of the Galactic bulge will be observed using a frame-linking method, which is different from the approach taken by both Hipparcos and Gaia, both developed at ESA. The target accuracy of the annual parallax and proper motion is approximately 10 μas and 10 μas yr-1, respectively, in the central region of the survey area of 0.3 × 0.3 deg2. The target accuracy of the annual parallax, ~ 50 μas, and that of the proper motion, ~ 50 μas yr-1, will be obtained within a region of 2 × 2 deg2. The observing region covers a field of approximately 3 × 3 deg2. The mission is required to continue for around three years to obtain reliable measurements. In the winter season, the angular distance between the Sun and the Galactic bulge region is small. Accordingly, we may have the chance to observe different regions which contain scientifically interesting targets, such as Cygnus X-1. If we are successful in observing the object over the course of a few weeks, the orbital elements of the star accompanying Cygnus X-1 can be resolved by Small-JASMINE.

  9. Approximations to galaxy star formation rate histories: properties and uses of two examples

    NASA Astrophysics Data System (ADS)

    Cohn, J. D.

    2018-05-01

    Galaxies evolve via a complex interaction of numerous different physical processes, scales and components. In spite of this, overall trends often appear. Simplified models for galaxy histories can be used to search for and capture such emergent trends, and thus to interpret and compare results of galaxy formation models to each other and to nature. Here, two approximations are applied to galaxy integrated star formation rate histories, drawn from a semi-analytic model grafted onto a dark matter simulation. Both a lognormal functional form and principal component analysis (PCA) approximate the integrated star formation rate histories fairly well. Machine learning, based upon simplified galaxy halo histories, is somewhat successful at recovering both fits. The fits to the histories give fixed time star formation rates which have notable scatter from their true final time rates, especially for quiescent and "green valley" galaxies, and more so for the PCA fit. For classifying galaxies into subfamilies sharing similar integrated histories, both approximations are better than using final stellar mass or specific star formation rate. Several subsamples from the simulation illustrate how these simple parameterizations provide points of contact for comparisons between different galaxy formation samples, or more generally, models. As a side result, the halo masses of simulated galaxies with early peak star formation rate (according to the lognormal fit) are bimodal. The galaxies with a lower halo mass at peak star formation rate appear to stall in their halo growth, even though they are central in their host halos.

  10. Decrease in early right alpha band phase synchronization and late gamma band oscillations in processing syntax in music.

    PubMed

    Ruiz, María Herrojo; Koelsch, Stefan; Bhattacharya, Joydeep

    2009-04-01

    The present study investigated the neural correlates associated with the processing of music-syntactical irregularities as compared with regular syntactic structures in music. Previous studies reported an early ( approximately 200 ms) right anterior negative component (ERAN) by traditional event-related-potential analysis during music-syntactical irregularities, yet little is known about the underlying oscillatory and synchronization properties of brain responses which are supposed to play a crucial role in general cognition including music perception. First we showed that the ERAN was primarily represented by low frequency (<8 Hz) brain oscillations. Further, we found that music-syntactical irregularities as compared with music-syntactical regularities, were associated with (i) an early decrease in the alpha band (9-10 Hz) phase synchronization between right fronto-central and left temporal brain regions, and (ii) a late ( approximately 500 ms) decrease in gamma band (38-50 Hz) oscillations over fronto-central brain regions. These results indicate a weaker degree of long-range integration when the musical expectancy is violated. In summary, our results reveal neural mechanisms of music-syntactic processing that operate at different levels of cortical integration, ranging from early decrease in long-range alpha phase synchronization to late local gamma oscillations. 2008 Wiley-Liss, Inc.

  11. Structure and evolution of Uranus and Neptune

    NASA Technical Reports Server (NTRS)

    Hubbard, W. B.; Macfarlane, J. J.

    1980-01-01

    Three-layer interior models of Uranus and Neptune with central rocky cores, mantles of water, methane, and ammonia (the 'ices'), and outer envelopes primarily composed of hydrogen and helium are presented. The models incorporate a new H2O equation of state based on experimental data which is considerably 'softer' than previous H2O equations of state. Corrections for interior temperatures approximately 5000 K are included in the models, and the thermal evolution of both planets is investigated using recent heat flow measurements. It is found that the evolutionary considerations are consistent with gravitational field data in supporting models with approximately solar abundances of 'ice' and 'rock'. Evolutionary considerations indicate that initial temperatures and luminosities for Uranus and Neptune were not substantially higher than the present value. Both planets apparently have relatively small approximately 1-2 earth masses) hydrogen-helium envelopes, with Neptune's envelope smaller than Uranus'. A monotonic trend is evident among the Jovian planets: all have central rock-ice cores of approximately 15 earth masses, but with hydrogen-helium envelopes which decrease in mass from Jupiter to Saturn to Uranus to Neptune.

  12. Overview of the hydraulic characteristics of the ITER Central Solenoid Model Coil conductors after 15 years of test campaigns

    NASA Astrophysics Data System (ADS)

    Brighenti, A.; Bonifetto, R.; Isono, T.; Kawano, K.; Russo, G.; Savoldi, L.; Zanino, R.

    2017-12-01

    The ITER Central Solenoid Model Coil (CSMC) is a superconducting magnet, layer-wound two-in-hand using Nb3Sn cable-in-conduit conductors (CICCs) with the central channel typical of ITER magnets, cooled with supercritical He (SHe) at ∼4.5 K and 0.5 MPa, operating for approximately 15 years at the National Institutes for Quantum and Radiological Science and Technology in Naka, Japan. The aim of this work is to give an overview of the issues related to the hydraulic performance of the three different CICCs used in the CSMC based on the extensive experimental database put together during the past 15 years. The measured hydraulic characteristics are compared for the different test campaigns and compared also to those coming from the tests of short conductor samples when available. It is shown that the hydraulic performance of the CSMC conductors did not change significantly in the sequence of test campaigns with more than 50 cycles up to 46 kA and 8 cooldown/warmup cycles from 300 K to 4.5 K. The capability of the correlations typically used to predict the friction factor of the SHe for the design and analysis of ITER-like CICCs is also shown.

  13. Learning to Leverage Student Thinking: What Novice Approximations Teach Us about Ambitious Practice

    ERIC Educational Resources Information Center

    Singer-Gabella, Marcy; Stengel, Barbara; Shahan, Emily; Kim, Min-Joung

    2016-01-01

    Central to ambitious teaching is a constellation of practices we have come to call "leveraging student thinking." In leveraging, teachers position students' understanding and reasoning as a central means to drive learning forward. While leveraging typically is described as a feature of mature practice, in this article we examine…

  14. 77 FR 14517 - Southern Star Central Gas Pipeline, Inc.; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-73-000] Southern Star..., 2012 Southern Star Central Gas Pipeline, Inc. (Southern Star), 4700 State Highway 56, Owensboro... Star proposes to replace 3 miles of 12-inch diameter XT pipeline by constructing approximately 3 miles...

  15. Improving the Procurement of Information Technology Commodities

    DTIC Science & Technology

    1994-04-12

    and 0 the federal government. Apply Electronic Data Interchange (EDI) to order processing at AVC. Implementing EDI at AVC and throughout the Air Force...ordering process by approximately 2 weeks. 4. Centralize the Central Order Processing Offices. By consolidating AVC and SSCs order processing responsibilities...Im plem entation ..................................................................................... 21 5. ORDER PROCESSING WITH EDI

  16. 75 FR 52818 - R.J. Corman Railroad Company/Central Kentucky Lines, LLC-Trackage Rights Exemption-CSX...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35386] R.J. Corman... to grant additional limited overhead trackage rights \\1\\ to R.J. Corman Railroad Company/Central... distance of approximately 17 miles.\\2\\ \\1\\ The original rights were obtained by R.J. Corman Railroad...

  17. Increasing Retention and Graduation Rates through a STEM Learning Community

    ERIC Educational Resources Information Center

    Dagley, Melissa; Georgiopoulos, Michael; Reece, Amber; Young, Cynthia

    2016-01-01

    The EXCEL Program began as a National Science Foundation-sponsored STEM Talent Expansion Program in 2006 and, because of its significant impact on retention of STEM majors, has since become an institutionalized program at the University of Central Florida. The University of Central Florida EXCEL Program annually recruits approximately 200…

  18. Distanze dei pianeti e dei satelliti nel sistema solare dedotte da massa, raggio equatoriale e densità del corpo centrale.

    NASA Astrophysics Data System (ADS)

    Lupato, G.

    1993-04-01

    The author illustrates an empirical correlation linking planet distances from the Sun to some physical characteristics of the central body such as mass, equatorial radius, density. Such a formula is applicable, with good approximation, also to the major planet satellite systems.

  19. Balanced Central Schemes for the Shallow Water Equations on Unstructured Grids

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron

    2004-01-01

    We present a two-dimensional, well-balanced, central-upwind scheme for approximating solutions of the shallow water equations in the presence of a stationary bottom topography on triangular meshes. Our starting point is the recent central scheme of Kurganov and Petrova (KP) for approximating solutions of conservation laws on triangular meshes. In order to extend this scheme from systems of conservation laws to systems of balance laws one has to find an appropriate discretization of the source terms. We first show that for general triangulations there is no discretization of the source terms that corresponds to a well-balanced form of the KP scheme. We then derive a new variant of a central scheme that can be balanced on triangular meshes. We note in passing that it is straightforward to extend the KP scheme to general unstructured conformal meshes. This extension allows us to recover our previous well-balanced scheme on Cartesian grids. We conclude with several simulations, verifying the second-order accuracy of our scheme as well as its well-balanced properties.

  20. Groundwater availability of the Central Valley Aquifer, California

    USGS Publications Warehouse

    Faunt, Claudia C.

    2009-01-01

    California's Central Valley covers about 20,000 square miles and is one of the most productive agricultural regions in the world. More than 250 different crops are grown in the Central Valley with an estimated value of $17 billion per year. This irrigated agriculture relies heavily on surface-water diversions and groundwater pumpage. Approximately one-sixth of the Nation's irrigated land is in the Central Valley, and about one-fifth of the Nation's groundwater demand is supplied from its aquifers. The Central Valley also is rapidly becoming an important area for California's expanding urban population. Since 1980, the population of the Central Valley has nearly doubled from 2 million to 3.8 million people. The Census Bureau projects that the Central Valley's population will increase to 6 million people by 2020. This surge in population has increased the competition for water resources within the Central Valley and statewide, which likely will be exacerbated by anticipated reductions in deliveries of Colorado River water to southern California. In response to this competition for water, a number of water-related issues have gained prominence: conservation of agricultural land, conjunctive use, artificial recharge, hydrologic implications of land-use change, and effects of climate variability. To provide information to stakeholders addressing these issues, the USGS Groundwater Resources Program made a detailed assessment of groundwater availability of the Central Valley aquifer system, that includes: (1) the present status of groundwater resources; (2) how these resources have changed over time; and (3) tools to assess system responses to stresses from future human uses and climate variability and change. This effort builds on previous investigations, such as the USGS Central Valley Regional Aquifer System and Analysis (CV-RASA) project and several other groundwater studies in the Valley completed by Federal, State and local agencies at differing scales. The principal product of this new assessment is a tool referred to as the Central Valley Hydrologic Model (CVHM) that accounts for integrated, variable water supply and demand, and simulates surface-water and groundwater-flow across the entire Central Valley system. The development of the CVHM comprised four major elements: (1) a comprehensive Geographic Information System (GIS) to compile, analyze and visualize data; (2) a texture model to characterize the aquifer system;(3) estimates of water-budget components by numerically modeling the hydrologic system with the Farm Process (FMP); and (4) simulations to assess and quantify hydrologic conditions.

  1. Changes in chemical components of aerosol particles in different haze regions in China from 2006 to 2013 and contribution of meteorological factors

    NASA Astrophysics Data System (ADS)

    Zhang, X. Y.; Wang, J. Z.; Wang, Y. Q.; Liu, H. L.; Sun, J. Y.; Zhang, Y. M.

    2015-11-01

    Since there have been individual reports of persistent haze-fog events in January 2013 in central-eastern China, questions on factors causing the drastic differences in changes in 2013 from changes in adjacent years have been raised. Changes in major chemical components of aerosol particles over the years also remain unclear. The extent of meteorological factors contributing to such changes is yet to be determined. The study intends to present the changes in daily based major water-soluble constituents, carbonaceous species, and mineral aerosol in PM10 at 13 stations within different haze regions in China from 2006 to 2013, which are associated with specific meteorological conditions that are highly related to aerosol pollution (parameterized as an index called Parameter Linking Aerosol Pollution and Meteorological Elements - PLAM). No obvious changes were found in annual mean concentrations of these various chemical components and PM10 in 2013, relative to 2012. By contrast, wintertime mass of these components was quite different. In Hua Bei Plain (HBP), sulfate, organic carbon (OC), nitrate, ammonium, element carbon (EC), and mineral dust concentrations in winter were approximately 43, 55, 28, 23, 21, and 130 μg m-3, respectively; these masses were approximately 2 to 4 times higher than those in background mass, which also exhibited a decline during 2006 to 2010 and then a rise till 2013. The mass of these concentrations and PM10, except minerals, respectively, increased by approximately 28 to 117 % and 25 % in January 2013 compared with that in January 2012. Thus, persistent haze-fog events occurred in January 2013, and approximately 60 % of this increase in component concentrations from 2012 to 2013 can be attributed to severe meteorological conditions in the winter of 2013. In the Yangtze River Delta (YRD) area, winter masses of these components, unlike HBP, have not significantly increase since 2010; PLAM were also maintained at a similar level without significant changes. In the Pearl River Delta (PRD) area, the regional background concentrations of the major chemical components were similar to those in the YRD, accounting for approximately 60-80 % of those in HBP. Since 2010, a decline has been found for winter concentrations, which can be partially attributable to persistently improving meteorological conditions and emission cutting with an emphasis on coal combustion in this area. In addition to the scattered and centralized coal combustion for heating, burning biomass fuels contributed to the large increase in concentrations of carbonaceous aerosol in major haze regions in winter, except in the PRD. No obvious changes were found for the proportions of each chemical components of PM10 from 2006 to 2013. Among all of the emissions recorded in chemical compositions in 2013, coal combustion was still the largest anthropogenic source of aerosol pollution in various areas in China, with a higher sulfate proportion of PM10 in most areas of China, and OC was normally ranked third. PM10 concentrations increased by approximately 25 % in January of 2013 relative to 2012, which caused persistent haze-fog events in HBP; emissions also reduced by approximately 35 % in Beijing and its vicinity (BIV) in late autumn of 2014, thereby producing the Asia Pacific Economic Cooperation (APEC) blue (extremely good air quality); thus, one can expect that the persistent haze-fog events would be reduced significantly in the BIV, if approx. one-third of the 2013 winter emissions were reduced, which can also be viewed as the upper limit of atmospheric aerosol pollution capacity in this area.

  2. Central California Valley Ecoregion: Chapter 17 in Status and trends of land change in the Western United States--1973 to 2000

    USGS Publications Warehouse

    Sleeter, Benjamin M.

    2012-01-01

    The Central California Valley Ecoregion, which covers approximately 45,983 km2 (17,754 mi2), is an elongated basin extending approximately 650 km north to south through central California (fig. 1) (Omernik, 1987; U.S. Environmental Protection Agency, 1997). The ecoregion is surrounded entirely by the Southern and Central California Chaparral and Oak Woodlands Ecoregion, which includes parts of the Coast Ranges to the west and which is bounded by the Sierra Nevada to the east. The Central California Valley Ecoregion accounts for more than half of California’s agricultural production value and is one of the most important agricultural regions in the country, with flat terrain, fertile soils, a favorable climate, and nearly 70 percent of its land in cultivation (Kuminoff and others, 2000; Sumner and others, 2003). Commodities produced in the region include milk and dairy, cattle and calves, cotton, almonds, citrus, and grapes, among others (U.S. Department of Agriculture, 2004; Johnston and McCalla, 2004; Kuminoff and others, 2000) (figs. 2A,B,C). Six of the top eight agricultural-producing counties in California are located at least partly within the Central California Valley Ecoregion (Kuminoff and others, 2000) (table 1). The Central California Valley Ecoregion is also home to nearly 5 million people spread throughout the region, including the major cities of Sacramento (state capital), Fresno, Bakersfield, and Stockton, California (U.S. Census Bureau, 2000) (fig. 1).

  3. UIT: Ultraviolet surface photometry of the spiral galaxy M74 (NGC 628)

    NASA Technical Reports Server (NTRS)

    Cornett, Robert H.; O'Connell, Robert W.; Greason, Michael R.; Offenberg, Joel D.; Angione, Ronald J.; Bohlin, Ralph C.; Cheng, K. P.; Roberts, Morton S.; Smith, Andrew M.; Smith, Eric P.

    1994-01-01

    Ultraviolet photometry, obtained from Ultraviolet Imaging Telescope (UIT) images at 1520 A (far-UV; magnitudes m(152)) and 2490 A (near-UV; magnitudes m(249)), of the spiral galaxy M74 (NGC 628) is compared with H-alpha, R, V, and B surface photometry and with models. M74's surface brightness profiles have a central peak with an exponential falloff; the exponential scale lengths of the profiles increase with decreasing wavelength for the broad-band images. The slope of the continuum-subtracted H-alpha profile is intermediate between those of far-UV and near-UV profiles, consistent with the related origins of H-alpha and UV emission in extreme Population I material. M74's color profiles all become bluer with increasing radius. The (m(152) - m(249)) color as measured by UIT averages near 0.0 (the color of an A0 star) over the central 20 sec radius and decreases from approximately -0.2 to approximately -0.4 from 20 sec to 200 sec. The spiral arms are the dominant component of the surface photometry colors; interarm regions are slightly redder. In the UV, M74's nuclear region resembles its disk/spiral arm material in colors and morphology, unlike galaxies such as M81. No UV 'bulge' is apparent. The m(152) - m(249) colors and models of M74's central region clearly demonstrate that there is no significant population of O or B stars present in the central 10 sec. M74's UV morphology and (m(152) - m(249)) color profiles are similar to those of M33, although M74 is approximately 0.5 mag redder. M81 has a smooth UV bulge which is much redder than the nuclear regions of M74 and M33. M74 is approximately 0.4 mag bluer than M81 in its outer disk, although M81 has bright UV sources only in spiral arms more than 5 kpc from its center. We investigate possible explanations for the color profiles of the galaxies and the differences among the galaxies: abundances; reddening due to internal dust; interplanetary magnetic field (IMF) variations, and the history of formation of the dominant generations of stars. Abundance and IMF variations do not produce large enough m(152) - m(249) or UV - V color differences. Comparing model UV/optical colors with those of M74 shows that M74's disk has undergone significant star formation over the past 500 Myr, and that either the star-formation history or the extinction varies systematically across M74's disk. Comparison of M74, M33, and M81 (UV - V) colors shows that M74 colors range from the bluest of M33's colors to the bluest of M81's. The failure of reddening models to cover the range of colors, and the known abundance range in such material, leads to the conclusion that star-formation history varies significantly as a function of radius in these galaxies, and that such variation is required to explain the range of colors observed in M74, M33, and M81.

  4. The Oncology Care Model: Perspectives From the Centers for Medicare & Medicaid Services and Participating Oncology Practices in Academia and the Community.

    PubMed

    Kline, Ron; Adelson, Kerin; Kirshner, Jeffrey J; Strawbridge, Larissa M; Devita, Marsha; Sinanis, Naralys; Conway, Patrick H; Basch, Ethan

    2017-01-01

    Cancer care delivery in the United States is often fragmented and inefficient, imposing substantial burdens on patients. Costs of cancer care are rising more rapidly than other specialties, with substantial regional differences in quality and cost. The Centers for Medicare & Medicaid Services (CMS) Innovation Center (CMMIS) recently launched the Oncology Care Model (OCM), which uses payment incentives and practice redesign requirements toward the goal of improving quality while controlling costs. As of March 2017, 190 practices were participating, with approximately 3,200 oncologists providing care for approximately 150,000 unique beneficiaries per year (approximately 20% of the Medicare Fee-for-Service population receiving chemotherapy for cancer). This article provides an overview of the program from the CMS perspective, as well as perspectives from two practices implementing OCM: an academic health system (Yale Cancer Center) and a community practice (Hematology Oncology Associates of Central New York). Requirements of OCM, as well as implementation successes, challenges, financial implications, impact on quality, and future visions, are provided from each perspective.

  5. Precision of Sensitivity in the Design Optimization of Indeterminate Structures

    NASA Technical Reports Server (NTRS)

    Patnaik, Surya N.; Pai, Shantaram S.; Hopkins, Dale A.

    2006-01-01

    Design sensitivity is central to most optimization methods. The analytical sensitivity expression for an indeterminate structural design optimization problem can be factored into a simple determinate term and a complicated indeterminate component. Sensitivity can be approximated by retaining only the determinate term and setting the indeterminate factor to zero. The optimum solution is reached with the approximate sensitivity. The central processing unit (CPU) time to solution is substantially reduced. The benefit that accrues from using the approximate sensitivity is quantified by solving a set of problems in a controlled environment. Each problem is solved twice: first using the closed-form sensitivity expression, then using the approximation. The problem solutions use the CometBoards testbed as the optimization tool with the integrated force method as the analyzer. The modification that may be required, to use the stiffener method as the analysis tool in optimization, is discussed. The design optimization problem of an indeterminate structure contains many dependent constraints because of the implicit relationship between stresses, as well as the relationship between the stresses and displacements. The design optimization process can become problematic because the implicit relationship reduces the rank of the sensitivity matrix. The proposed approximation restores the full rank and enhances the robustness of the design optimization method.

  6. Phenology and Growth dynamics of Avicennia marina in the Central Red Sea

    PubMed Central

    Almahasheer, Hanan; Duarte, Carlos M.; Irigoien, Xabier

    2016-01-01

    The formation of nodes, stem elongation and the phenology of stunted Avicennia marina was examined in the Central Red Sea, where Avicennia marina is at the limit of its distribution range and submitted to extremely arid conditions with salinity above 38 psu and water temperature as high as 35° C. The annual node production was rather uniform among locations averaging 9.59 node y−1, which resulted in a plastocron interval, the interval in between production of two consecutive nodes along a stem, of 38 days. However, the internodal length varied significantly between locations, resulting in growth differences possibly reflecting the environmental conditions of locations. The reproductive cycle lasted for approximately 12 months, and was characterized by peak flowering and propagule development in November and January. These phenological observations provide a starting point for research and restoration programs on the ecology of mangroves in the Central Red Sea, while the plastochrone index reported here would allow calculations of the growth and production of the species from simple morphological measurements. PMID:27892956

  7. Geophysical modeling of the northern Appalachian Brompton-Cameron, Central Maine, and Avalon terranes under the New Jersey Coastal Plain

    USGS Publications Warehouse

    Maguire, T.J.; Sheridan, R.E.; Volkert, R.A.

    2004-01-01

    A regional terrane map of the New Jersey Coastal Plain basement was constructed using seismic, drilling, gravity and magnetic data. The Brompton-Cameron and Central Maine terranes were coalesced as one volcanic island arc terrane before obducting onto Laurentian, Grenville age, continental crust in the Taconian orogeny [Rankin, D.W., 1994. Continental margin of the eastern United States: past and present. In: Speed, R.C., (Ed.), Phanerozoic Evolution of North American Continent-Ocean Transitions. DNAG Continent-Ocean Transect Volume. Geological Society of America, Boulder, Colorado, pp. 129-218]. Volcanic island-arc rocks of the Avalon terrane are in contact with Central Maine terrane rocks in southern Connecticut where the latter are overthrust onto the Brompton-Cameron terrane, which is thrust over Laurentian basement. Similarities of these allochthonous island arc terranes (Brompton-Cameron, Central Maine, Avalon) in lithology, fauna and age suggest that they are faulted segments of the margin of one major late Precambrian to early Paleozoic, high latitude peri-Gondwana island arc designated as "Avalonia", which collided with Laurentia in the early to middle Paleozoic. The Brompton Cameron, Central Maine, and Avalon terranes are projected as the basement under the eastern New Jersey Coastal Plain based on drill core samples of metamorphic rocks of active margin/magmatic arc origin. A seismic reflection profile across the New York Bight traces the gentle dipping (approximately 20 degrees) Cameron's Line Taconian suture southeast beneath allochthonous Avalon and other terranes to a 4 sec TWTT depth (approximately 9 km) where the Avalonian rocks are over Laurentian crust. Gentle up-plunge (approximately 5 degrees) projections to the southwest bring the Laurentian Grenville age basement and the drift-stage early Paleozoic cover rocks to windows in Burlington Co. at approximately 1 km depth and Cape May Co. at approximately 2 km depths. The antiformal Shellburne Falls and Chester domes and Chain Lakes-Pelham dome-Bronson Hill structural trends, and the synformal Connecticut Valley-Gaspe structural trend can be traced southwest into the New Jersey Coastal Plain basement. A Mesozoic rift basin, the "Sandy Hook basin", and associated eastern boundary fault is identified, based upon gravity modeling, in the vicinity of Sandy Hook, New Jersey. The thickness of the rift-basin sedimentary rocks contained within the "Sandy Hook basin" is approximately 4.7 km, with the basin extending offshore to the east of the New Jersey coast. Gravity modeling indicates a deep rift basin and the magnetic data indicates a shallow magnetic basement caused by magnetic diabase sills and/or basalt flows contained within the rift-basin sedimentary rocks. The igneous sills and/or flows may be the eastward continuation of the Watchung and Palisades bodies. ?? 2004 Elsevier Ltd. All rights reserved.

  8. The Effect of Size and Species on Lens Intracellular Hydrostatic Pressure

    PubMed Central

    Gao, Junyuan; Sun, Xiurong; Moore, Leon C.; Brink, Peter R.; White, Thomas W.; Mathias, Richard T.

    2013-01-01

    Purpose. Previous experiments showed that mouse lenses have an intracellular hydrostatic pressure that varied from 335 mm Hg in central fibers to 0 mm Hg in surface cells. Model calculations predicted that in larger lenses, all else equal, pressure should increase as the lens radius squared. To test this prediction, lenses of different radii from different species were studied. Methods. All studies were done in intact lenses. Intracellular hydrostatic pressures were measured with a microelectrode-manometer–based system. Membrane conductances were measured by frequency domain impedance analysis. Intracellular Na+ concentrations were measured by injecting the Na+-sensitive dye sodium-binding benzofuran isophthalate. Results. Intracellular hydrostatic pressures were measured in lenses from mice, rats, rabbits, and dogs with radii (cm) 0.11, 0.22, 0.49, and 0.57, respectively. In each species, pressure varied from 335 ± 6 mm Hg in central fiber cells to 0 mm Hg in surface cells. Further characterization of transport in lenses from mice and rats showed that the density of fiber cell gap junction channels was approximately the same, intracellular Na+ concentrations varied from 17 mM in central fiber cells to 7 mM in surface cells, and intracellular voltages varied from −45 mV in central fiber cells to −60 mV in surface cells. Fiber cell membrane conductance was a factor of 2.7 times larger in mouse than in rat lenses. Conclusions. Intracellular hydrostatic pressure is an important physiological parameter that is regulated in lenses from these different species. The most likely mechanism of regulation is to reduce the density of open Na+-leak channels in fiber cells of larger lenses. PMID:23211824

  9. Neural network classification technique and machine vision for bread crumb grain evaluation

    NASA Astrophysics Data System (ADS)

    Zayas, Inna Y.; Chung, O. K.; Caley, M.

    1995-10-01

    Bread crumb grain was studied to develop a model for pattern recognition of bread baked at Hard Winter Wheat Quality Laboratory (HWWQL), Grain Marketing and Production Research Center (GMPRC). Images of bread slices were acquired with a scanner in a 512 multiplied by 512 format. Subimages in the central part of the slices were evaluated by several features such as mean, determinant, eigen values, shape of a slice and other crumb features. Derived features were used to describe slices and loaves. Neural network programs of MATLAB package were used for data analysis. Learning vector quantization method and multivariate discriminant analysis were applied to bread slices from what of different sources. A training and test sets of different bread crumb texture classes were obtained. The ranking of subimages was well correlated with visual judgement. The performance of different models on slice recognition rate was studied to choose the best model. The recognition of classes created according to human judgement with image features was low. Recognition of arbitrarily created classes, according to porosity patterns, with several feature patterns was approximately 90%. Correlation coefficient was approximately 0.7 between slice shape features and loaf volume.

  10. Individual Differences in Algebraic Cognition: Relation to the Approximate Number and Sematic Memory Systems

    PubMed Central

    Geary, David C.; Hoard, Mary K.; Nugent, Lara; Rouder, Jeffrey N.

    2015-01-01

    The relation between performance on measures of algebraic cognition and acuity of the approximate number system (ANS) and memory for addition facts was assessed for 171 (92 girls) 9th graders, controlling parental education, sex, reading achievement, speed of numeral processing, fluency of symbolic number processing, intelligence, and the central executive component of working memory. The algebraic tasks assessed accuracy in placing x,y pairs in the coordinate plane, speed and accuracy of expression evaluation, and schema memory for algebra equations. ANS acuity was related to accuracy of placements in the coordinate plane and expression evaluation, but not schema memory. Frequency of fact-retrieval errors was related to schema memory but not coordinate plane or expression evaluation accuracy. The results suggest the ANS may contribute to or is influenced by spatial-numerical and numerical only quantity judgments in algebraic contexts, whereas difficulties in committing addition facts to long-term memory may presage slow formation of memories for the basic structure of algebra equations. More generally, the results suggest different brain and cognitive systems are engaged during the learning of different components of algebraic competence, controlling demographic and domain general abilities. PMID:26255604

  11. Lectures on Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Weinberg, Steven

    2015-09-01

    Preface; Notation; 1. Historical introduction; 2. Particle states in a central potential; 3. General principles of quantum mechanics; 4. Spin; 5. Approximations for energy eigenstates; 6. Approximations for time-dependent problems; 7. Potential scattering; 8. General scattering theory; 9. The canonical formalism; 10. Charged particles in electromagnetic fields; 11. The quantum theory of radiation; 12. Entanglement; Author index; Subject index.

  12. Sedimentation and subsidence patterns in the central and north basins of Lake Baikal from seismic stratigraphy

    USGS Publications Warehouse

    Moore, T.C.; Klitgord, Kim D.; Golmshtok, A.J.; Weber, E.

    1997-01-01

    Comparison of sedimentation patterns, basement subsidence, and faulting histories in the north and central basins of Lake Baikal aids in developing an interbasinal seismic stratigraphy that reveals the early synrift evolution of the central portion of the Baikal rift, a major continental rift system. Although there is evidence that the central and northern rift basins evolved at approximately the same time, their sedimentation histories are markedly different. Primary sediment sources for the initial rift phase were from the east flank of the rift; two major deltas developed adjacent to the central basin: the Selenga delta at the south end and the Barguzin delta at the north end. The Barguzin River system, located at the accommodation zone between the central and north basins, also fed into the southern part of the north basin and facilitated the stratigraphic linkage of the two basins. A shift in the regional tectonic environment in the mid Pliocene(?) created a second rift phase distinguished by more rapid subsidence and sediment accumulation in the north basin and by increased subsidence and extensive faulting in the central basin. The Barguzin delta ceased formation and parts of the old delta system were isolated within the north basin and on Academic Ridge. These isolated deltaic deposits provide a model for the development of hydrocarbon plays within ancient rift systems. In this second tectonic phase, the dominant sediment fill in the deeper and more rapidly subsiding north basin shifted from the flexural (eastern) margin to axial transport from the Upper Angara River at the north end of the basin.

  13. Broadscale postseismic deformation and lower crustal relaxation in the central Bayankala Block (central Tibetan Plateau) observed using InSAR data

    NASA Astrophysics Data System (ADS)

    Zhao, Dezheng; Qu, Chunyan; Shan, Xinjian; Zuo, Ronghu; Liu, Yunhua; Gong, Wenyu; Zhang, Guohong

    2018-04-01

    We have generated a more than 500 km long postseismic deformation rate map and cumulative displacement time series in the central Bayankala Block of the Tibetan Plateau using ENVISAT/ASAR data from 2003 to 2010 by the π-RATE stacking algorithm. This rate map spans a period of ∼7.2 years and reveals that postseismic motion of 2001 Kokoxili earthquake exhibits a striking signal, dominating crustal deformation of the central Bayankala Block with a cross-fault magnitude ∼9-11 mm/yr in line of sight (LOS) (∼93.1°E). The southern and northern parts of the postseismic deformation field exhibit different patterns and variable magnitudes, reflecting asymmetry of the displacement distribution. Postseismic motion affects eastward extrusion of the central Bayankala Block, which reaches ∼15 km north of the Ganzi-Yushu fault. To further investigate viscoelastic relaxation of the lower crust in this area after approximately two years, E-M, E-M-M and E-S models are constructed. The result shows that the best fit viscosity for the lower crust is about 1 × 1019 Pa·s. Comparison between cumulative displacements resolved by these three models shows that viscoelastic relaxation of the lower crust makes the most significant contribution to postseismic stress relaxation after 2001 event.

  14. Central Corneal Thickness in Children

    PubMed Central

    2011-01-01

    Objective To report the central corneal thickness (CCT) in healthy white, African-American, and Hispanic children from birth to 17 years of age. Design Prospective observational multicenter study. Central corneal thickness was measured with a hand-held contact pachymeter. Results Two thousand seventy-nine children were included in the study, with ages ranging from day of birth to 17 years. Included were 807 white, 494 Hispanic, and 474 African-American individuals, in addition to Asian, unknown and mixed race individuals. African-American children had thinner corneas on average than that of both white (p< .001) and Hispanic children (p< .001) by approximately 20 micrometers. Thicker median CCT was observed with each successive year of age from age 1 to 11 years, with year-to-year differences steadily decreasing and reaching a plateau after age 11 at 573 micrometers in white and Hispanic children and 551 micrometers in African-American children. For every 100 micrometers of thicker CCT measured, the intraocular pressure was 1.5 mmHg higher on average (p< 0.001). For every diopter of increased myopic refractive error (p< 0.001) CCT was 1 micrometer thinner on average. Conclusions Median CCT increases with age from 1 to 11 years with the greatest increase present in the youngest age groups. African-American children on average have thinner central corneas than white and Hispanic children, while white and Hispanic children demonstrate similar central corneal thickness. PMID:21911662

  15. The Relationship between Brainstem Temporal Processing and Performance on Tests of Central Auditory Function in Children with Reading Disorders

    ERIC Educational Resources Information Center

    Billiet, Cassandra R.; Bellis, Teri James

    2011-01-01

    Purpose: Studies using speech stimuli to elicit electrophysiologic responses have found approximately 30% of children with language-based learning problems demonstrate abnormal brainstem timing. Research is needed regarding how these responses relate to performance on behavioral tests of central auditory function. The purpose of the study was to…

  16. Visiting the Digital Divide: Women Entrepreneurs in Central America

    ERIC Educational Resources Information Center

    Tapper, Helena

    2006-01-01

    Micro and small enterprises comprise approximately 60-70% of enterprises in South and Central America. Most of these enterprises, particularly micro enterprises, are managed and owned by women. These women for the most part lack both skills and training in the use of computers and the Internet, and access to the use of information and…

  17. Radiation necrosis causing failure of automatic ventilation during sleep with central sleep apnea

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Udwadia, Z.F.; Athale, S.; Misra, V.P.

    A patient operated upon for a midline cerebellar hemangioblastoma developed failure of automatic respiration during sleep, together with central sleep apnea syndrome, approximately two years after receiving radiation therapy to the brain. Clinical and CT scan findings were compatible with a diagnosis of radiation necrosis as the cause of his abnormal respiratory control.

  18. Forest invasive adaptive management on national wildlife refuge lands in the central hardwood region

    Treesearch

    Damon B. Lesmeister; Sean M. Blomquist; Eric V. Lonsdorf; Daniel Wood; Perry J. Williams; Brad Pendley; Karen E. Mangan; Benjamin A. Walker

    2014-01-01

    Approximately 2.4 million acres of National Wildlife Refuge System lands are impacted by invasive plants and are the primary challenge for habitat management in the Central Hardwood region. In 2011, biologists, managers, and contracted support staff from six national wildlife refuges in southern Indiana, Illinois, and Missouri developed an adaptive management project...

  19. Update on GPS-Acoustics Measurements on the Continental Slope of the Cascadia Subduction Zone

    NASA Astrophysics Data System (ADS)

    Chadwell, C. D.

    2017-12-01

    Land-based GPS measurements suggest the megathrust is locked offshore along the Cascadia Subduction Zone. However, land-based data alone lack geometric resolution to constrain the how the slip is distributed. GPS-Acoustic measurements can provide these constraints, but using traditional GPS-Acoustic approaches employing a ship is costly. Wave Gliders, a wave- and solar-powered, remotely-piloted sea surface platform, provide a low cost method for collecting GPS-A data. We have adapted GPS-Acoustic technology to the Wave Glider and in 2016 began annual measurements at three sites in the Cascadia Subduction Zone (CSZ). Here, we review positioning results collected during summer 2017 at two sites on the continental slope of the Cascadia Subduction Zone: One site is approximately 45 NM offshore central Oregon and the other approximately 50 NM offshore central Washington State. A third site is approximately 90 NM offshore central Oregon on the incoming Juan de Fuca plate. We will report on initial results of the GPS-A data collection and operational experiences of the missions in 2016 and 2017. Wave Glider based GPS-A measurement have the potential to significantly increase the number and frequency of measurements of strain accumulation in Cascadia Subduction Zone and elsewhere.

  20. The performance of the ZEUS central tracking detector z-by-timing electronics in a transputer based data acquisition system

    NASA Astrophysics Data System (ADS)

    Foster, B.; Heath, G. P.; Llewellyn, T. J.; Gingrich, D. M.; Harnew, N.; Hallam-Baker, P. M.; Khatri, T.; McArthur, I. C.; Morawitz, P.; Nash, J.; Shield, P. D.; Topp-Jorgensen, S.; Wilson, F. F.; Allen, D. B.; Carter, R. C.; Jeffs, M. D.; Morrissey, M. C.; Quinton, S. P. H.; Lane, J. B.; Postranecky, M.

    1993-05-01

    The Central Tracking Detector of the ZEUS experiment employs a time difference technique to measure the z coordinate of each hit. The method provides fast, three-dimensional space point measurements which are used as input to all levels of the ZEUS trigger. Such a tracking trigger is essential in order to discriminate against events with vertices lying outside the nominal electron-proton interaction region. Since the beam crossing interval of the HERA collider is 96 ns, all data must be pipelined through the front-end readout electronics. Subsequent data aquisition employs a novel technique which utilizes a network of approximately 120 INMOS transputers to process the data in parallel. The z-by-timing method and its data aquisition have been employed successfully in recording and reconstructing tracks from electron-proton interactions in ZEUS.

  1. A possible relation between flare activity in super-luminous supernovae and gamma-ray bursts

    NASA Astrophysics Data System (ADS)

    Yu, Yun-Wei; Li, Shao-Ze

    2017-09-01

    Significant undulations appear in the light curve of a recently discovered super-luminous supernova (SLSN) SN 2015bn after the first peak, while the underlying profile of the light curve can be explained well by a continuous energy supply from a central engine, possibly the spin-down of a millisecond magnetar. We propose that these undulations are caused by an intermittent pulsed energy supply, indicating the energetic flare activity of the central engine of the SLSN. Many post-burst flares were discovered during X-ray afterglow observations of gamma-ray bursts (GRBs). We find that the SLSN flares described here approximately obey the empirical correlation between the luminosity and time-scale of GRB flares, extrapolated to the relevant longer time-scales of SLSN flares. This somewhat confirms the possible connection between these two different phenomena, as recently suggested by Yu et al.

  2. Partitioning of centralized integrated flight/propulsion control design for decentralized implementation

    NASA Technical Reports Server (NTRS)

    Garg, Sanjay

    1993-01-01

    The notion of partitioning a centralized controller into a decentralized, hierarchical structure suitable for integrated flight/propulsion control (IFPC) implementation is discussed. A systematic procedure is developed for determining partitioned airframe and engine subsystem controllers (subcontrollers), with the desired interconnection structure, that approximate the closed-loop performance and robustness characteristics of a given centralized controller. The procedure is demonstrated by application to IFPC design for a short take-off and vertical landing (STOVL) aircraft in the landing-approach-to-hover-transition flight phase.

  3. Pharmacotherapy for Adults with Tumors of the Central Nervous System

    PubMed Central

    Schor, Nina F.

    2009-01-01

    Tumors of the adult central nervous system are among the most common and most chemoresistant neoplasms. Malignant tumors of the brain and spinal cord collectively account for approximately 1.3% of all cancers and 2.2% of all cancer-related deaths. Novel pharmacological approaches to nervous system tumors are urgently needed. This review presents the current approaches and challenges to successful pharmacotherapy of adults with malignant tumors of the central nervous system and discusses novel approaches aimed at overcoming these challenges. PMID:19091301

  4. Compatible diagonal-norm staggered and upwind SBP operators

    NASA Astrophysics Data System (ADS)

    Mattsson, Ken; O'Reilly, Ossian

    2018-01-01

    The main motivation with the present study is to achieve a provably stable high-order accurate finite difference discretisation of linear first-order hyperbolic problems on a staggered grid. The use of a staggered grid makes it non-trivial to discretise advective terms. To overcome this difficulty we discretise the advective terms using upwind Summation-By-Parts (SBP) operators, while the remaining terms are discretised using staggered SBP operators. The upwind and staggered SBP operators (for each order of accuracy) are compatible, here meaning that they are based on the same diagonal norms, allowing for energy estimates to be formulated. The boundary conditions are imposed using a penalty (SAT) technique, to guarantee linear stability. The resulting SBP-SAT approximations lead to fully explicit ODE systems. The accuracy and stability properties are demonstrated for linear hyperbolic problems in 1D, and for the 2D linearised Euler equations with constant background flow. The newly derived upwind and staggered SBP operators lead to significantly more accurate numerical approximations, compared with the exclusive usage of (previously derived) central-difference first derivative SBP operators.

  5. A taxonomy and comparison of parallel block multi-level preconditioners for the incompressible Navier-Stokes equations.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shadid, John Nicolas; Elman, Howard; Shuttleworth, Robert R.

    2007-04-01

    In recent years, considerable effort has been placed on developing efficient and robust solution algorithms for the incompressible Navier-Stokes equations based on preconditioned Krylov methods. These include physics-based methods, such as SIMPLE, and purely algebraic preconditioners based on the approximation of the Schur complement. All these techniques can be represented as approximate block factorization (ABF) type preconditioners. The goal is to decompose the application of the preconditioner into simplified sub-systems in which scalable multi-level type solvers can be applied. In this paper we develop a taxonomy of these ideas based on an adaptation of a generalized approximate factorization of themore » Navier-Stokes system first presented in [25]. This taxonomy illuminates the similarities and differences among these preconditioners and the central role played by efficient approximation of certain Schur complement operators. We then present a parallel computational study that examines the performance of these methods and compares them to an additive Schwarz domain decomposition (DD) algorithm. Results are presented for two and three-dimensional steady state problems for enclosed domains and inflow/outflow systems on both structured and unstructured meshes. The numerical experiments are performed using MPSalsa, a stabilized finite element code.« less

  6. Kinematics of current region fragmentation in semi-inclusive deeply inelastic scattering

    DOE PAGES

    Boglione, M.; Collins, J.; Gamberg, L.; ...

    2017-01-16

    Different kinematical regions of semi-inclusive deeply inelastic scattering (SIDIS) processes correspond to different underlying partonic pictures, and it is important to understand the transition between them. We find criteria in semi-inclusive deeply inelastic scattering (SIDIS) for identifying the current fragmentation region — the kinematical region where a factorization picture with fragmentation functions is appropriate, especially for studies of transverse-momentum-dependent (TMD) functions. This region is distinguished from the central (soft) and target fragmentation regions. The basis of our argument is in the errors in approximations used in deriving factorization. As compared with previous work, we show that it is essential tomore » take account of the transverse momentum of the detected hadron, and we find a much more restricted range for genuine current fragmentation. As a result, we show that it is important to develop an extended factorization formulation to treat hadronization in the central region, as well as the current and target fragmentation regions, and to obtain a unified formalism spanning all rapidities for the detected hadron.« less

  7. 3D FEA of cemented glass fiber and cast posts with various dental cements in a maxillary central incisor.

    PubMed

    Madfa, Ahmed A; Al-Hamzi, Mohsen A; Al-Sanabani, Fadhel A; Al-Qudaimi, Nasr H; Yue, Xiao-Guang

    2015-01-01

    This study aimed to analyse and compare the stability of two dental posts cemented with four different luting agents by examining their shear stress transfer through the FEM. Eight three-dimensional finite element models of a maxillary central incisor restored with glass fiber and Ni-Cr alloy cast dental posts. Each dental post was luted with zinc phosphate, Panavia resin, super bond C&B resin and glass ionomer materials. Finite element models were constructed and oblique loading of 100 N was applied. The distribution of shear stress was investigated at posts and cement/dentine interfaces using ABAQUS/CAE software. The peak shear stress for glass fiber post models minimized approximately three to four times of those for Ni-Cr alloy cast post models. There was negligible difference in peak of shear stress when various cements were compared, irrespective of post materials. The shear stress had same trend for all cement materials. This study found that the glass fiber dental post reduced the shear stress concentration at interfacial of post and cement/dentine compared to Ni-Cr alloy cast dental post.

  8. Inflammation, Iron, Energy Failure, and Oxidative Stress in the Pathogenesis of Multiple Sclerosis

    PubMed Central

    Haider, Lukas

    2015-01-01

    Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. Different trigger pathologies have been suggested by the primary cytodegenerative “inside-out” and primary inflammation-driven “outside-in” hypotheses. Recent data indicate that mitochondrial injury and subsequent energy failure are key factors in the induction of demyelination and neurodegeneration. The brain weighs only a few percent of the body mass but accounts for approximately 20% of the total basal oxygen consumption of mitochondria. Oxidative stress induces mitochondrial injury in patients with multiple sclerosis and energy failure in the central nervous system of susceptible individuals. The interconnected mechanisms responsible for free radical production in patients with multiple sclerosis are as follows: (i) inflammation-induced production of free radicals by activated immune cells, (ii) liberation of iron from the myelin sheets during demyelination, and (iii) mitochondrial injury and thus energy failure-related free radical production. In the present review, the different sources of oxidative stress and their relationships to patients with multiple sclerosis considering tissue injury mechanisms and clinical aspects have been discussed. PMID:26106458

  9. Basement-involved faults and deep structures in the West Philippine Basin: constrains from gravity field

    NASA Astrophysics Data System (ADS)

    Wang, Gang; Jiang, Suhua; Li, Sanzhong; Zhang, Huixuan; Lei, Jianping; Gao, Song; Zhao, Feiyu

    2017-06-01

    To reveal the basement-involved faults and deep structures of the West Philippine Basin (WPB), the gravitational responses caused by these faults are observed and analyzed based on the latest spherical gravity model: WGM2012 Model. By mapping the free-air and Bouguer gravity anomalies, several main faults and some other linear structures are located and observed in the WPB. Then, by conducting a 2D discrete multi-scale wavelet decomposition, the Bouguer anomalies are decomposed into the first- to eighth-order detail and approximation fields (the first- to eighth-order Details and Approximations). The first- to third-order Details reflect detailed and localized geological information of the crust at different depths, and of which the higher-order reflects gravity field of the deeper depth. The first- to fourth-order Approximations represent the regional gravity fields at different depths of the crust, respectively. The fourth-order Approximation represents the regional gravity fluctuation caused by the density inhomogeneity of Moho interface. Therefore, taking the fourth-order Approximation as input, and adopting Parker-Oldenburg interactive inversion, We calculated the depth of Moho interface in the WPB. Results show that the Moho interface depth in the WPB ranges approximately from 8 to 12 km, indicating that there is typical oceanic crust in the basin. In the Urdaneta Plateau and the Benham Rise, the Moho interface depths are about 14 and 16 km, respectively, which provides a piece of evidence to support that the Banham Rise could be a transitional crust caused by a large igneous province. The second-order vertical derivative and the horizontal derivatives in direction 0° and 90° are computed based on the data of the third-order Detail, and most of the basement-involved faults and structures in the WPB, such as the Central Basin Fault Zone, the Gagua Ridge, the Luzon-Okinawa Fault Zone, and the Mindanao Fault Zone are interpreted by the gravity derivatives.

  10. Geology and mineral resources of the North-Central Idaho Sagebrush Focal Area: Chapter C in Mineral resources of the Sagebrush Focal Areas of Idaho, Montana, Nevada, Oregon, Utah, and Wyoming

    USGS Publications Warehouse

    Lund, Karen; Zürcher, Lukas; Hofstra, Albert H.; Van Gosen, Bradley S.; Benson, Mary Ellen; Box, Stephen E.; Anderson, Eric D.; Bleiwas, Donald I.; DeAngelo, Jacob; Drake, Ronald M.; Fernette, Gregory L.; Giles, Stuart A.; Glen, Jonathan M. G.; Haacke, Jon E.; Horton, John D.; John, David A.; Robinson, Gilpin R.; Rockwell, Barnaby W.; San Juan, Carma A.; Shaffer, Brian N.; Smith, Steven M.; Williams, Colin F.

    2016-10-04

    SummaryThe U.S. Department of the Interior has proposed to withdraw approximately 10 million acres of Federal lands from mineral entry (subject to valid existing rights) from 12 million acres of lands defined as Sagebrush Focal Areas (SFAs) in Idaho, Montana, Nevada, Oregon, Utah, and Wyoming (for further discussion on the lands involved see Scientific Investigations Report 2016–5089–A). The purpose of the proposed action is to protect the greater sage-grouse (Centrocercus urophasianus) and its habitat from potential adverse effects of locatable mineral exploration and mining. The U.S. Geological Survey Sagebrush Mineral-Resource Assessment (SaMiRA) project was initiated in November 2015 and supported by the Bureau of Land Management to (1) assess locatable mineral-resource potential and (2) to describe leasable and salable mineral resources for the seven SFAs and Nevada additions.This chapter summarizes the current status of locatable, leasable, and salable mineral commodities and assesses the potential of locatable minerals in the North-Central Idaho SFA, which extends from east-central to south-central Idaho. The geologically complex area is composed of many different rock units that locally contain potential mineral resources.

  11. Postglacial recolonization in a cold climate specialist in western Europe: patterns of genetic diversity in the adder (Vipera berus) support the central-marginal hypothesis.

    PubMed

    Ursenbacher, Sylvain; Guillon, Michaël; Cubizolle, Hervé; Dupoué, Andréaz; Blouin-Demers, Gabriel; Lourdais, Olivier

    2015-07-01

    Understanding the impact of postglacial recolonization on genetic diversity is essential in explaining current patterns of genetic variation. The central-marginal hypothesis (CMH) predicts a reduction in genetic diversity from the core of the distribution to peripheral populations, as well as reduced connectivity between peripheral populations. While the CMH has received considerable empirical support, its broad applicability is still debated and alternative hypotheses predict different spatial patterns of genetic diversity. Using microsatellite markers, we analysed the genetic diversity of the adder (Vipera berus) in western Europe to reconstruct postglacial recolonization. Approximate Bayesian Computation (ABC) analyses suggested a postglacial recolonization from two routes: a western route from the Atlantic Coast up to Belgium and a central route from the Massif Central to the Alps. This cold-adapted species likely used two isolated glacial refugia in southern France, in permafrost-free areas during the last glacial maximum. Adder populations further from putative glacial refugia had lower genetic diversity and reduced connectivity; therefore, our results support the predictions of the CMH. Our study also illustrates the utility of highly variable nuclear markers, such as microsatellites, and ABC to test competing recolonization hypotheses. © 2015 John Wiley & Sons Ltd.

  12. Size-dependent standard deviation for growth rates: empirical results and theoretical modeling.

    PubMed

    Podobnik, Boris; Horvatic, Davor; Pammolli, Fabio; Wang, Fengzhong; Stanley, H Eugene; Grosse, I

    2008-05-01

    We study annual logarithmic growth rates R of various economic variables such as exports, imports, and foreign debt. For each of these variables we find that the distributions of R can be approximated by double exponential (Laplace) distributions in the central parts and power-law distributions in the tails. For each of these variables we further find a power-law dependence of the standard deviation sigma(R) on the average size of the economic variable with a scaling exponent surprisingly close to that found for the gross domestic product (GDP) [Phys. Rev. Lett. 81, 3275 (1998)]. By analyzing annual logarithmic growth rates R of wages of 161 different occupations, we find a power-law dependence of the standard deviation sigma(R) on the average value of the wages with a scaling exponent beta approximately 0.14 close to those found for the growth of exports, imports, debt, and the growth of the GDP. In contrast to these findings, we observe for payroll data collected from 50 states of the USA that the standard deviation sigma(R) of the annual logarithmic growth rate R increases monotonically with the average value of payroll. However, also in this case we observe a power-law dependence of sigma(R) on the average payroll with a scaling exponent beta approximately -0.08 . Based on these observations we propose a stochastic process for multiple cross-correlated variables where for each variable (i) the distribution of logarithmic growth rates decays exponentially in the central part, (ii) the distribution of the logarithmic growth rate decays algebraically in the far tails, and (iii) the standard deviation of the logarithmic growth rate depends algebraically on the average size of the stochastic variable.

  13. Unexpected early extinction of the European pond turtle (Emys orbicularis) in Sweden and climatic impact on its Holocene range.

    PubMed

    Sommer, Robert S; Lindqvist, Charlotte; Persson, Arne; Bringsøe, Henrik; Rhodin, Anders G J; Schneeweiss, Norbert; Siroký, Pavel; Bachmann, Lutz; Fritz, Uwe

    2009-03-01

    Using ancient DNA sequences of subfossil European pond turtles (Emys orbicularis) from Britain, Central and North Europe and accelerator mass spectrometry radiocarbon dating for turtle remains from most Swedish sites, we provide evidence for a Holocene range expansion of the pond turtle from the southeastern Balkans into Britain, Central Europe and Scandinavia, according to the 'grasshopper pattern' of Hewitt. Northeastern Europe and adjacent Asia were colonized from another refuge located further east. With increasing annual mean temperatures, pond turtles reached southern Sweden approximately 9800 years ago. Until approximately 5500 years ago, rising temperatures facilitated a further range expansion up to Ostergötland, Sweden (approximately 58 degrees 30'N). However, around 5500 years ago pond turtle records suddenly terminate in Sweden, some 1500 years before the Holocene thermal maximum ended in Scandinavia and distinctly earlier than previously thought. This extinction coincides with a temporary cooling oscillation during the Holocene thermal maximum and is likely related to lower summer temperatures deteriorating reproductive success. Although climatic conditions improved later again, recolonization of Sweden from southern source populations was prevented by the Holocene submergence of the previous land connection via the Danish Straits that occurred approximately 8500 years ago.

  14. On the cost of approximating and recognizing a noise perturbed straight line or a quadratic curve segment in the plane. [central processing units

    NASA Technical Reports Server (NTRS)

    Cooper, D. B.; Yalabik, N.

    1975-01-01

    Approximation of noisy data in the plane by straight lines or elliptic or single-branch hyperbolic curve segments arises in pattern recognition, data compaction, and other problems. The efficient search for and approximation of data by such curves were examined. Recursive least-squares linear curve-fitting was used, and ellipses and hyperbolas are parameterized as quadratic functions in x and y. The error minimized by the algorithm is interpreted, and central processing unit (CPU) times for estimating parameters for fitting straight lines and quadratic curves were determined and compared. CPU time for data search was also determined for the case of straight line fitting. Quadratic curve fitting is shown to require about six times as much CPU time as does straight line fitting, and curves relating CPU time and fitting error were determined for straight line fitting. Results are derived on early sequential determination of whether or not the underlying curve is a straight line.

  15. Earth Observations

    NASA Image and Video Library

    2010-09-20

    ISS024-E-015121 (20 Sept. 2010) --- Twitchell Canyon Fire in central Utah is featured in this image photographed by an Expedition 24 crew member on the International Space Station (ISS). The Twitchell Canyon Fire near central Utah?s Fishlake National Forest is reported to have an area of approximately 13,383 hectares (approximately 134 square kilometers, or 33,071 acres). This detailed image shows smoke plumes generated by several fire spots close to the southwestern edge of the burned area. The fire was started by a lightning strike on July 20, 2010. Whereas many of the space station images of Earth are looking straight down (nadir), this photograph was exposed at an angle. The space station was located over a point approximately 509 kilometers (316 miles) to the northeast, near the Colorado/Wyoming border, at the time the image was taken on Sept. 20. Southwesterly winds were continuing to extend smoke plumes from the fire to the northeast. While the Twitchell Canyon region is sparsely populated, Interstate Highway 15 is visible at upper left.

  16. Postseismic Gravity Change After the 2006-2007 Great Earthquake Doublet and Constraints on the Asthenosphere Structure in the Central Kuril Islands

    NASA Technical Reports Server (NTRS)

    Shin-Chan, Han; Sauber, Jeanne; Pollitz, Fred

    2016-01-01

    Large earthquakes often trigger viscoelastic adjustment for years to decades depending on the rheological properties and the nature and spatial extent of coseismic stress. The 2006 Mw8.3 thrust and 2007 Mw8.1 normal fault earthquakes of the central Kuril Islands resulted in significant postseismic gravity change in GRACE but without a discernible coseismic gravity change. The gravity increase of approximately 4 micro-Gal, observed consistently from various GRACE solutions around the epicentral area during 2007-2015, is interpreted as resulting from gradual seafloor uplift by (is) approximately 6 cm produced by postseismic relaxation. The GRACE data are best fit with a model of 25-35 km for the elastic thickness and approximately 10(exp 18) Pa s for the Maxwell viscosity of the asthenosphere. The large measurable postseismic gravity change (greater than coseismic change) emphasizes the importance of viscoelastic relaxation in understanding tectonic deformation and fault-locking scenarios in the Kuril subduction zone.

  17. Air pollution dispersion models for human exposure predictions in London.

    PubMed

    Beevers, Sean D; Kitwiroon, Nutthida; Williams, Martin L; Kelly, Frank J; Ross Anderson, H; Carslaw, David C

    2013-01-01

    The London household survey has shown that people travel and are exposed to air pollutants differently. This argues for human exposure to be based upon space-time-activity data and spatio-temporal air quality predictions. For the latter, we have demonstrated the role that dispersion models can play by using two complimentary models, KCLurban, which gives source apportionment information, and Community Multi-scale Air Quality Model (CMAQ)-urban, which predicts hourly air quality. The KCLurban model is in close agreement with observations of NO(X), NO(2) and particulate matter (PM)(10/2.5), having a small normalised mean bias (-6% to 4%) and a large Index of Agreement (0.71-0.88). The temporal trends of NO(X) from the CMAQ-urban model are also in reasonable agreement with observations. Spatially, NO(2) predictions show that within 10's of metres of major roads, concentrations can range from approximately 10-20 p.p.b. up to 70 p.p.b. and that for PM(10/2.5) central London roadside concentrations are approximately double the suburban background concentrations. Exposure to different PM sources is important and we predict that brake wear-related PM(10) concentrations are approximately eight times greater near major roads than at suburban background locations. Temporally, we have shown that average NO(X) concentrations close to roads can range by a factor of approximately six between the early morning minimum and morning rush hour maximum periods. These results present strong arguments for the hybrid exposure model under development at King's and, in future, for in-building models and a model for the London Underground.

  18. A comparative analysis of centralized waiting lists for patients without a primary care provider implemented in six Canadian provinces: study protocol.

    PubMed

    Breton, Mylaine; Green, Michael; Kreindler, Sara; Sutherland, Jason; Jbilou, Jalila; Wong, Sabrina T; Shaw, Jay; Crooks, Valorie A; Contandriopoulos, Damien; Smithman, Mélanie Ann; Brousselle, Astrid

    2017-01-21

    Having a regular primary care provider (i.e., family physician or nurse practitioner) is widely considered to be a prerequisite for obtaining healthcare that is timely, accessible, continuous, comprehensive, and well-coordinated with other parts of the healthcare system. Yet, 4.6 million Canadians, approximately 15% of Canada's population, are unattached; that is, they do not have a regular primary care provider. To address the critical need for attachment, especially for more vulnerable patients, six Canadian provinces have implemented centralized waiting lists for unattached patients. These waiting lists centralize unattached patients' requests for a primary care provider in a given territory and match patients with providers. From the little information we have on each province's centralized waiting list, we know the way they work varies significantly from province to province. The main objective of this study is to compare the different models of centralized waiting lists for unattached patients implemented in six provinces of Canada to each other and to available scientific knowledge to make recommendations on ways to improve their design in an effort to increase attachment of patients to a primary care provider. A logic analysis approach developed in three steps will be used. Step 1: build logic models that describe each province's centralized waiting list through interviews with key stakeholders in each province; step 2: develop a conceptual framework, separate from the provincially informed logic models, that identifies key characteristics of centralized waiting lists for unattached patients and factors influencing their implementation through a literature review and interviews with experts; step 3: compare the logic models to the conceptual framework to make recommendations to improve centralized waiting lists in different provinces during a pan Canadian face-to-face exchange with decision-makers, clinicians and researchers. This study is based on an inter-provincial learning exchange approach where we propose to compare centralized waiting lists and analyze variations in strategies used to increase attachment to a regular primary care provider. Fostering inter-provincial healthcare systems connectivity to improve centralized waiting lists' practices across Canada can lever attachment to a regular provider for timely access to continuous, comprehensive and coordinated healthcare for all Canadians and particular for those who are vulnerable.

  19. Seismic characteristics of central Brazil crust and upper mantle: A deep seismic refraction study

    USGS Publications Warehouse

    Soares, J.E.; Berrocal, J.; Fuck, R.A.; Mooney, W.D.; Ventura, D.B.R.

    2006-01-01

    A two-dimensional model of the Brazilian central crust and upper mantle was obtained from the traveltime interpretation of deep seismic refraction data from the Porangatu and Cavalcante lines, each approximately 300 km long. When the lines were deployed, they overlapped by 50 km, forming an E-W transect approximately 530 km long across the Tocantins Province and western Sa??o Francisco Craton. The Tocantins Province formed during the Neoproterozoic when the Sa??o Francisco, the Paranapanema, and the Amazon cratons collided, following the subduction of the former Goia??s ocean basin. Average crustal VP and VP/VS ratios, Moho topography, and lateral discontinuities within crustal layers suggest that the crust beneath central Brazil can be associated with major geological domains recognized at the surface. The Moho is an irregular interface, between 36 and 44 km deep, that shows evidences of first-order tectonic structures. The 8.05 and 8.23 km s-1 P wave velocities identify the upper mantle beneath the Porangatu and Cavalcante lines, respectively. The observed seismic features allow for the identification of (1) the crust has largely felsic composition in the studied region, (2) the absence of the mafic-ultramafic root beneath the Goia??s magmatic arc, and (3) block tectonics in the foreland fold-and-thrust belt of the northern Brasi??lia Belt during the Neoproterozoic. Seismic data also suggested that the Bouguer gravimetric discontinuities are mainly compensated by differences in mass distribution within the lithospheric mantle. Finally, the Goia??s-Tocantins seismic belt can be interpreted as a natural seismic alignment related to the Neoproterozoic mantle domain. Copyright 2006 by the American Geophysical Union.

  20. Field Review of Fish Habitat Improvement Projects in Central Idaho.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beschta, Robert L.; Griffith, Jack; Wesche, Thomas A.

    1993-05-01

    The goal of this field review was to provide information to the Bonneville Power Administration (BPA) regarding previous and ongoing fish habitat improvement projects in central Idaho. On July 14, 1992, the review team met at the Sawtooth National Recreation Area office near Ketchum, Idaho, for a slide presentation illustrating several habitat projects during their construction phases. Following the slide presentation, the review team inspected fish habitat projects that have been implemented in the last several years in the Stanley Basin and adjacent valleys. At each site the habitat project was described to the field team and a brief periodmore » for project inspection followed. The review team visited approximately a dozen sites on the Challis, Sawtooth, and Boise National Forests over a period of approximately two and a half days. There are two objectives of this review namely to summarize observations for specific field sites and to provide overview commentary regarding the BPA habitat improvement program in central Idaho.« less

  1. Microgliomatosis in a Schnauzer dog.

    PubMed

    Willard, M D; Delahunta, A

    1982-04-01

    Microgliomatosis was found in the central nervous system of a 7-year-old male Standard Schnauzer. History, neurologic examination, laboratory tests and electrodiagnostics could not localize the disease process in the central nervous system. The animal was not treated, continued to deteriorate, and was euthanatized approximately 8 weeks after clinical signs were first detected. Diagnosis was made upon histologic examination of the brain.

  2. Diameter Growth Models Using Minnesota Forest Inventory and Analysis Data

    Treesearch

    Veronica C. Lessard; Ronald E. McRoberts; Margaret R. Holdaway

    2001-01-01

    The Forest Inventory and Analysis (FIA) program of the USDA Forest Service North Central Research Station (NCRS) has begun replacing the 12-to 13-yr periodic inventory cycles for the states in the North Central region with annual inventories featuring measurement of approximately 20% of all plots in each of the 11 states each year. State reports on summaries of the...

  3. Monitoring biological control agents and leafy spurge populations along the Smith River in Montana, USA

    Treesearch

    J. Birdsall; G. Markin; T. Kalaris; J. Runyon

    2013-01-01

    The Smith River originates in west central Montana and flows north approximately 100 miles before joining the Missouri River. The central 60 miles of the river flows through a relatively inaccessible, forested, scenic limestone canyon famous for its trout fishing. Because of its popularity, the area was designated Montana's first and only controlled river, with...

  4. The importance of federal grazing allotments to central Sierran oak woodland permittees: a first approximation

    Treesearch

    Adriana Sulak; Lynn Huntsinger

    2002-01-01

    The interlinkage of privately owned foothill oak woodlands and federal grazing permits in the central Sierra Nevada is examined. Knowledge of the viability of the range livestock industry is important to large-scale conservation of hardwood rangelands in the Sierran foothills. Because ranches in the Sierra often use USDA Forest Service grazing allotments, efforts at...

  5. Apollo 16 spacecraft touches down in the central Pacific Ocean

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The Apollo 16 spacecraft touches down in the central Pacific Ocean at the end of its mission. Splashdown occured at 1:45:06 p.m., Thursday, April 27, 1972, at coordinates of 00:45.2 degrees south latitude and 156:11.4 degrees west longitude, a point approximately 215 miles southeast of Christmas Island. All its parachutes are fully deployed.

  6. Gravity, aeromagnetic and rock-property data of the central California Coast Ranges

    USGS Publications Warehouse

    Langenheim, V.E.

    2014-01-01

    Gravity, aeromagnetic, and rock-property data were collected to support geologic-mapping, water-resource, and seismic-hazard studies for the central California Coast Ranges. These data are combined with existing data to provide gravity, aeromagnetic, and physical-property datasets for this region. The gravity dataset consists of approximately 18,000 measurements. The aeromagnetic dataset consists of total-field anomaly values from several detailed surveys that have been merged and gridded at an interval of 200 m. The physical property dataset consists of approximately 800 density measurements and 1,100 magnetic-susceptibility measurements from rock samples, in addition to previously published borehole gravity surveys from Santa Maria Basin, density logs from Salinas Valley, and intensities of natural remanent magnetization.

  7. Morphology and time variation of the Jovian Far UV aurora: Hubble Space Telescope observations

    NASA Technical Reports Server (NTRS)

    Gerard, Jean-Claude; Dols, Vincent; Paresce, Francesco; Prange, Renee

    1993-01-01

    High spatial resolution images of the north polar region of Jupiter have been obtained with the Faint Object Camera (FOC) on board the Hubble Space Telescope (HST). The first set of two images collected 87 min apart in February 1992 shows a bright (approximately or equal to 180 kR) emission superimposed on the background in rotation with the planet. Both Ly alpha images show common regions of enhanced emission but differences are also observed, possibly due to temporal variations. The second group of images obtained on June 23 and 26, 1992 isolates a spectral region near 153 nm dominated by the H2 Lyman bands and continuum. Both pictures exhibit a narrow arc structure fitting the L = 30 magnetotail field line footprint in the morning sector and a broader diffuse aurora in the afternoon. They show no indication of an evening twilight enhancement. Although the central meridian longitudes were similar, significant differences are seen in the two exposures, especially in the region of diffuse emission, and interpreted as signatures of temporal variations. The total power radiated in the H2 bands is approximately or equal to 2 x 10(exp 12) W, in agreement with previous UV spectrometer observations. The high local H2 emission rates (approximately 450 kR) imply a particle precipitation carrying an energy flux of about 5 x 10(exp -2) W/sq m.

  8. Experts' understanding of partial derivatives using the partial derivative machine

    NASA Astrophysics Data System (ADS)

    Roundy, David; Weber, Eric; Dray, Tevian; Bajracharya, Rabindra R.; Dorko, Allison; Smith, Emily M.; Manogue, Corinne A.

    2015-12-01

    [This paper is part of the Focused Collection on Upper Division Physics Courses.] Partial derivatives are used in a variety of different ways within physics. Thermodynamics, in particular, uses partial derivatives in ways that students often find especially confusing. We are at the beginning of a study of the teaching of partial derivatives, with a goal of better aligning the teaching of multivariable calculus with the needs of students in STEM disciplines. In this paper, we report on an initial study of expert understanding of partial derivatives across three disciplines: physics, engineering, and mathematics. We report on the central research question of how disciplinary experts understand partial derivatives, and how their concept images of partial derivatives differ, with a focus on experimentally measured quantities. Using the partial derivative machine (PDM), we probed expert understanding of partial derivatives in an experimental context without a known functional form. In particular, we investigated which representations were cued by the experts' interactions with the PDM. Whereas the physicists and engineers were quick to use measurements to find a numeric approximation for a derivative, the mathematicians repeatedly returned to speculation as to the functional form; although they were comfortable drawing qualitative conclusions about the system from measurements, they were reluctant to approximate the derivative through measurement. On a theoretical front, we found ways in which existing frameworks for the concept of derivative could be expanded to include numerical approximation.

  9. Exact relations between homoclinic and periodic orbit actions in chaotic systems

    NASA Astrophysics Data System (ADS)

    Li, Jizhou; Tomsovic, Steven

    2018-02-01

    Homoclinic and unstable periodic orbits in chaotic systems play central roles in various semiclassical sum rules. The interferences between terms are governed by the action functions and Maslov indices. In this article, we identify geometric relations between homoclinic and unstable periodic orbits, and derive exact formulas expressing the periodic orbit classical actions in terms of corresponding homoclinic orbit actions plus certain phase space areas. The exact relations provide a basis for approximations of the periodic orbit actions as action differences between homoclinic orbits with well-estimated errors. This enables an explicit study of relations between periodic orbits, which results in an analytic expression for the action differences between long periodic orbits and their shadowing decomposed orbits in the cycle expansion.

  10. A computer software system for the generation of global ocean tides including self-gravitation and crustal loading effects

    NASA Technical Reports Server (NTRS)

    Estes, R. H.

    1977-01-01

    A computer software system is described which computes global numerical solutions of the integro-differential Laplace tidal equations, including dissipation terms and ocean loading and self-gravitation effects, for arbitrary diurnal and semidiurnal tidal constituents. The integration algorithm features a successive approximation scheme for the integro-differential system, with time stepping forward differences in the time variable and central differences in spatial variables. Solutions for M2, S2, N2, K2, K1, O1, P1 tidal constituents neglecting the effects of ocean loading and self-gravitation and a converged M2, solution including ocean loading and self-gravitation effects are presented in the form of cotidal and corange maps.

  11. The role of external features in face recognition with central vision loss: A pilot study

    PubMed Central

    Bernard, Jean-Baptiste; Chung, Susana T.L.

    2016-01-01

    Purpose We evaluated how the performance for recognizing familiar face images depends on the internal (eyebrows, eyes, nose, mouth) and external face features (chin, outline of face, hairline) in individuals with central vision loss. Methods In Experiment 1, we measured eye movements for four observers with central vision loss to determine whether they fixated more often on the internal or the external features of face images while attempting to recognize the images. We then measured the accuracy for recognizing face images that contained only the internal, only the external, or both internal and external features (Experiment 2), and for hybrid images where the internal and external features came from two different source images (Experiment 3), for five observers with central vision loss and four age-matched control observers. Results When recognizing familiar face images, approximately 40% of the fixations of observers with central vision loss were centered on the external features of faces. The recognition accuracy was higher for images containing only external features (66.8±3.3% correct) than for images containing only internal features (35.8±15.0%), a finding contradicting that of control observers. For hybrid face images, observers with central vision loss responded more accurately to the external features (50.4±17.8%) than to the internal features (9.3±4.9%), while control observers did not show the same bias toward responding to the external features. Conclusions Contrary to people with normal vision who rely more on the internal features of face images for recognizing familiar faces, individuals with central vision loss show a higher dependence on using external features of face images. PMID:26829260

  12. The Role of External Features in Face Recognition with Central Vision Loss.

    PubMed

    Bernard, Jean-Baptiste; Chung, Susana T L

    2016-05-01

    We evaluated how the performance of recognizing familiar face images depends on the internal (eyebrows, eyes, nose, mouth) and external face features (chin, outline of face, hairline) in individuals with central vision loss. In experiment 1, we measured eye movements for four observers with central vision loss to determine whether they fixated more often on the internal or the external features of face images while attempting to recognize the images. We then measured the accuracy for recognizing face images that contained only the internal, only the external, or both internal and external features (experiment 2) and for hybrid images where the internal and external features came from two different source images (experiment 3) for five observers with central vision loss and four age-matched control observers. When recognizing familiar face images, approximately 40% of the fixations of observers with central vision loss was centered on the external features of faces. The recognition accuracy was higher for images containing only external features (66.8 ± 3.3% correct) than for images containing only internal features (35.8 ± 15.0%), a finding contradicting that of control observers. For hybrid face images, observers with central vision loss responded more accurately to the external features (50.4 ± 17.8%) than to the internal features (9.3 ± 4.9%), whereas control observers did not show the same bias toward responding to the external features. Contrary to people with normal vision who rely more on the internal features of face images for recognizing familiar faces, individuals with central vision loss show a higher dependence on using external features of face images.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ni, Nina, E-mail: nina.ni@yale.edu; Mojibian, Hamid; Pollak, Jeffrey

    To compare the rates of central venous stenosis in patients undergoing hemodialysis who underwent disruption of fibrin sheath with percutaneous transluminal angioplasty balloons and those who underwent over-the-wire catheter exchange. This study is a retrospective review of 209 percutaneous transluminal angioplasty balloon disruption and 1304 over-the-wire catheter exchange procedures performed in 753 patients. Approval from the Human Investigations Committee was obtained for this study. Up to 10-year follow-up was performed. A {chi}{sup 2} test was used to compare the rates of central venous stenosis after balloon disruption versus catheter exchange. A t-test was used to compare time to central venousmore » stenosis development. Of the 753 patients in the study, 127 patients underwent balloon disruption of fibrin sheath and 626 had catheter exchange. Within the balloon disruption group, 18 (14.2%) of 127 patients subsequently developed central venous stenosis, compared with 44 (7.0%) of 626 in the catheter exchange group (P < 0.01, {chi}{sup 2} test). Time to central venous stenosis development was approximately 3 years in both groups and not significantly different (1371 and 1010 days, P = 0.20). A total of 25.2% of patients in the balloon disruption group had four or more subsequent catheter exchanges, versus 12.6% in the catheter exchange group (P < 0.01, {chi}{sup 2} test). In conclusions, there is a possible association between percutaneous transluminal angioplasty balloon disruption of fibrin sheath and late-onset central venous stenosis. Because venography was not routinely performed in catheter exchange patients, future randomized studies are necessary to confirm these findings.« less

  14. A Well-Balanced Central-Upwind Scheme for the 2D Shallow Water Equations on Triangular Meshes

    NASA Technical Reports Server (NTRS)

    Bryson, Steve; Levy, Doron

    2004-01-01

    We are interested in approximating solutions of the two-dimensional shallow water equations with a bottom topography on triangular meshes. We show that there is a certain flexibility in choosing the numerical fluxes in the design of semi-discrete Godunov-type central schemes. We take advantage of this fact to generate a new second-order, central-upwind method for the two-dimensional shallow water equations that is well-balanced. We demonstrate the accuracy of our method as well as its balance properties in a variety of examples.

  15. Artificial recharge to the Floridan aquifer system, Orlando Area, Central Florida

    USGS Publications Warehouse

    German, E.R.; Bradner, L.A.

    1989-01-01

    Approximately 400 drainage wells exist in Orange County, central Florida. The rate of recharge through drainage wells is limited by the rate of surface flow to the wells; the hydraulic properties of weirs, overflow pipes, and well casings; or the water level above the top of the casing. The rate commonly is not limited by the hydraulic properties of the very transmissive aquifer system.

  16. Planting and care of fine hardwood seedlings: Planting hardwood seedlings in the Central Hardwood Region.

    Treesearch

    Paula M. Pijut

    2003-01-01

    Forest tree planting in the United States on public and private land exceeded 2.6 million acres in 1999. Of that total, approximately 1.3 million acres (48 percent) were planted by private individuals (AF & PA 2001). In the Central Hardwood Region forest tree planting by private landowners exceeded 100,000 acres in 1999. Trees are planted for various reasons...

  17. Distribution of fine roots of ponderosa pine and Douglas-fir in a central Idaho forest

    Treesearch

    Gabriel Dumm; Lauren Fins; Russell T. Graham; Theresa B. Jain

    2008-01-01

    This study describes soil horizon depth and fine root distribution in cores collected at two distances from the boles of Douglas-fir and ponderosa pine trees at a study site in a central Idaho forest. Concentration and content of fine roots extracted from soil cores were compared among species, soil horizons, tree size, and distance from bole. Approximately 80% of...

  18. Research on the relation of EEG signal chaos characteristics with high-level intelligence activity of human brain

    PubMed Central

    2010-01-01

    Using phase space reconstruct technique from one-dimensional and multi-dimensional time series and the quantitative criterion rule of system chaos, and combining the neural network; analyses, computations and sort are conducted on electroencephalogram (EEG) signals of five kinds of human consciousness activities (relaxation, mental arithmetic of multiplication, mental composition of a letter, visualizing a 3-dimensional object being revolved about an axis, and visualizing numbers being written or erased on a blackboard). Through comparative studies on the determinacy, the phase graph, the power spectra, the approximate entropy, the correlation dimension and the Lyapunov exponent of EEG signals of 5 kinds of consciousness activities, the following conclusions are shown: (1) The statistic results of the deterministic computation indicate that chaos characteristic may lie in human consciousness activities, and central tendency measure (CTM) is consistent with phase graph, so it can be used as a division way of EEG attractor. (2) The analyses of power spectra show that ideology of single subject is almost identical but the frequency channels of different consciousness activities have slight difference. (3) The approximate entropy between different subjects exist discrepancy. Under the same conditions, the larger the approximate entropy of subject is, the better the subject's innovation is. (4) The results of the correlation dimension and the Lyapunov exponent indicate that activities of human brain exist in attractors with fractional dimensions. (5) Nonlinear quantitative criterion rule, which unites the neural network, can classify different kinds of consciousness activities well. In this paper, the results of classification indicate that the consciousness activity of arithmetic has better differentiation degree than that of abstract. PMID:20420714

  19. Research on the relation of EEG signal chaos characteristics with high-level intelligence activity of human brain.

    PubMed

    Wang, Xingyuan; Meng, Juan; Tan, Guilin; Zou, Lixian

    2010-04-27

    Using phase space reconstruct technique from one-dimensional and multi-dimensional time series and the quantitative criterion rule of system chaos, and combining the neural network; analyses, computations and sort are conducted on electroencephalogram (EEG) signals of five kinds of human consciousness activities (relaxation, mental arithmetic of multiplication, mental composition of a letter, visualizing a 3-dimensional object being revolved about an axis, and visualizing numbers being written or erased on a blackboard). Through comparative studies on the determinacy, the phase graph, the power spectra, the approximate entropy, the correlation dimension and the Lyapunov exponent of EEG signals of 5 kinds of consciousness activities, the following conclusions are shown: (1) The statistic results of the deterministic computation indicate that chaos characteristic may lie in human consciousness activities, and central tendency measure (CTM) is consistent with phase graph, so it can be used as a division way of EEG attractor. (2) The analyses of power spectra show that ideology of single subject is almost identical but the frequency channels of different consciousness activities have slight difference. (3) The approximate entropy between different subjects exist discrepancy. Under the same conditions, the larger the approximate entropy of subject is, the better the subject's innovation is. (4) The results of the correlation dimension and the Lyapunov exponent indicate that activities of human brain exist in attractors with fractional dimensions. (5) Nonlinear quantitative criterion rule, which unites the neural network, can classify different kinds of consciousness activities well. In this paper, the results of classification indicate that the consciousness activity of arithmetic has better differentiation degree than that of abstract.

  20. Measuring (subglacial) bedform orientation, length, and longitudinal asymmetry - Method assessment.

    PubMed

    Jorge, Marco G; Brennand, Tracy A

    2017-01-01

    Geospatial analysis software provides a range of tools that can be used to measure landform morphometry. Often, a metric can be computed with different techniques that may give different results. This study is an assessment of 5 different methods for measuring longitudinal, or streamlined, subglacial bedform morphometry: orientation, length and longitudinal asymmetry, all of which require defining a longitudinal axis. The methods use the standard deviational ellipse (not previously applied in this context), the longest straight line fitting inside the bedform footprint (2 approaches), the minimum-size footprint-bounding rectangle, and Euler's approximation. We assess how well these methods replicate morphometric data derived from a manually mapped (visually interpreted) longitudinal axis, which, though subjective, is the most typically used reference. A dataset of 100 subglacial bedforms covering the size and shape range of those in the Puget Lowland, Washington, USA is used. For bedforms with elongation > 5, deviations from the reference values are negligible for all methods but Euler's approximation (length). For bedforms with elongation < 5, most methods had small mean absolute error (MAE) and median absolute deviation (MAD) for all morphometrics and thus can be confidently used to characterize the central tendencies of their distributions. However, some methods are better than others. The least precise methods are the ones based on the longest straight line and Euler's approximation; using these for statistical dispersion analysis is discouraged. Because the standard deviational ellipse method is relatively shape invariant and closely replicates the reference values, it is the recommended method. Speculatively, this study may also apply to negative-relief, and fluvial and aeolian bedforms.

  1. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications.

    PubMed

    Araújo, J; Gonzalez-Mira, E; Egea, M A; Garcia, M L; Souto, E B

    2010-06-30

    The purpose of this study was to develop a novel nanostructured lipid carrier (NLC) for the intravitreal-targeting delivery of triamcinolone acetonide (TA) by direct ocular instillation. A five-level central composite rotable design was used to study the influence of four different variables on the physicochemical characteristics of NLCs. The analysis of variance (ANOVA) statistical test was used to assess the optimization of NLC production parameters. The systems were produced by high pressure homogenization using Precirol ATO5 and squalene as solid and liquid lipids respectively, and Lutrol F68 as surfactant. Homogenization at 600 bar for 3 cycles of the optimized formulation resulted in the production of small NLC (mean diameter < 200 nm) with a homogeneous particle size distribution (polydispersity index (PI) approximately 0.1), of negatively charged surface (approximately |45| mV) and high entrapment efficiency (approximately 95%). Surface morphology was assessed by SEM which revealed fairly spherical shape. DSC, WAXS and FT-IR analyses confirmed that TA was mostly entrapped into the NLC, characterized by an amorphous matrix. In vivo Draize test showed no signs of ocular toxicity. 2010 Elsevier B.V. All rights reserved.

  2. A Systematic Analysis of the Sensitivity of Plasma Pharmacokinetics to Detect Differences in the Pulmonary Performance of Inhaled Fluticasone Propionate Products Using a Model-Based Simulation Approach.

    PubMed

    Weber, Benjamin; Hochhaus, Guenther

    2015-07-01

    The role of plasma pharmacokinetics (PK) for assessing bioequivalence at the target site, the lung, for orally inhaled drugs remains unclear. A validated semi-mechanistic model, considering the presence of mucociliary clearance in central lung regions, was expanded for quantifying the sensitivity of PK studies in detecting differences in the pulmonary performance (total lung deposition, central-to-peripheral lung deposition ratio, and pulmonary dissolution characteristics) between test (T) and reference (R) inhaled fluticasone propionate (FP) products. PK bioequivalence trials for inhaled FP were simulated based on this PK model for a varying number of subjects and T products. The statistical power to conclude bioequivalence when T and R products are identical was demonstrated to be 90% for approximately 50 subjects. Furthermore, the simulations demonstrated that PK metrics (area under the concentration time curve (AUC) and C max) are capable of detecting differences between T and R formulations of inhaled FP products when the products differ by more than 20%, 30%, and 25% for total lung deposition, central-to-peripheral lung deposition ratio, and pulmonary dissolution characteristics, respectively. These results were derived using a rather conservative risk assessment approach with an error rate of <10%. The simulations thus indicated that PK studies might be a viable alternative to clinical studies comparing pulmonary efficacy biomarkers for slowly dissolving inhaled drugs. PK trials for pulmonary efficacy equivalence testing should be complemented by in vitro studies to avoid false positive bioequivalence assessments that are theoretically possible for some specific scenarios. Moreover, a user-friendly web application for simulating such PK equivalence trials with inhaled FP is provided.

  3. A Monte Carlo model reveals independent signaling at central glutamatergic synapses.

    PubMed Central

    Franks, Kevin M; Bartol, Thomas M; Sejnowski, Terrence J

    2002-01-01

    We have developed a biophysically realistic model of receptor activation at an idealized central glutamatergic synapse that uses Monte Carlo techniques to simulate the stochastic nature of transmission following release of a single synaptic vesicle. For the a synapse with 80 AMPA and 20 NMDA receptors, a single quantum, with 3000 glutamate molecules, opened approximately 3 NMDARs and 20 AMPARs. The number of open receptors varied directly with the total number of receptors, and the fraction of open receptors did not depend on the ratio of co-localized AMPARs and NMDARs. Variability decreased with increases in either total receptor number or quantal size, and differences between the variability of AMPAR and NMDAR responses were due solely to unequal numbers of receptors at the synapse. Despite NMDARs having a much higher affinity for glutamate than AMPARs, quantal release resulted in similar occupancy levels in both receptor types. Receptor activation increased with number of transmitter molecules released or total receptor number, whereas occupancy levels were only dependent on quantal size. Tortuous diffusion spaces reduced the extent of spillover and the activation of extrasynaptic receptors. These results support the conclusion that signaling is spatially independent within and between central glutamatergic synapses. PMID:12414671

  4. Corneal subbasal nerve fiber regeneration in myopic patients after laser in situ keratomileusis★

    PubMed Central

    Deng, Shijing; Wang, Mengmeng; Zhang, Fengju; Sun, Xuguang; Hou, Wenbo; Guo, Ning

    2012-01-01

    A total of 26 myopic patients (52 eyes) underwent laser in situ keratomileusis. In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the corneal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients. Meanwhile, new fibers were also found to directly regenerate from deep in the stroma in some cases. Approximately 94% of regenerated corneal subbasal nerve fibers (73/78 eyes) regrew vertically into the peripheral central 6-mm circle area 1 month after surgery, 78% (28/36 eyes) grew into the central 3–6 mm area at 2 months, and 23% into the central 3-mm circle area at 3 months. In addition, there was no significant difference in corneal subbasal nerve fiber regenerative capacity between the basic fibroblast growth factor group and the 20% (v/v) deproteinized extract of calf blood group. The majority of corneal subbasal nerve fiber regeneration occurred from the stump of corneal subbasal nerve fibers outside the corneal flap, and the remaining growth occurred deep within the stroma. PMID:25657693

  5. Congenital transmission of Trypanosoma cruzi in central Brazil. A study of 1,211 individuals born to infected mothers

    PubMed Central

    Luquetti, Alejandro O; Tavares, Suelene Brito do Nascimento; Siriano, Liliane da Rocha; de Oliveira, Rozângela Amaral; Campos, Dayse Elizabeth; de Morais, Cicilio Alves; de Oliveira, Enio Chaves

    2015-01-01

    Transmission of Trypanosoma cruzi during pregnancy is estimated to occur in less than 20% of infected mothers; however, the etiopathogenesis is not completely understood. The Centre for Studies on Chagas Disease provides confirmation of T. cruzi infection for individuals living in central Brazil. In this retrospective hospital-based study, all requests for diagnosis of T. cruzi infection in individuals less than 21 years old from 1994-2014 were searched. We end with 1,211 individuals and their respective infected mothers. Congenital transmission of infection was confirmed in 24 individuals (2%) in central Brazil, an area where the main T. cruzi lineage circulating in humans is TcII. This low prevalence of congenital Chagas disease is discussed in relation to recent findings in the south region of Brazil, where TcV is the main lineage and congenital transmission has a higher prevalence (approximately 5%), similar to frequencies reported in Argentina, Paraguay and Bolivia. This is the first report to show geographical differences in the rates of congenital transmission of T. cruzi and the relationship between the prevalence of congenital transmission and the type of Tc prevalent in each region. PMID:25993506

  6. Peak streamflows and runoff volumes for the Central United States, February through September, 2011: Chapter C in 2011 floods of the central United States

    USGS Publications Warehouse

    Holmes, Robert R.; Wiche, Gregg J.; Koenig, Todd A.; Sando, Steven K.

    2013-01-01

    During 2011, excessive precipitation resulted in widespread flooding in the Central United States with 33 fatalities and approximately $4.2 billion in damages reported in the Souris/Red River of the North (Souris/Red) and Mississippi River Basins. At different times, beginning in late February 2011 and extending through September 2011, various rivers in these basins had major flooding, with some locations receiving multiple rounds of flooding. Peak streamflow records were broken at 105 streamgages in the Souris/Red and Mississippi River Basins and annual runoff volume records set at 47 of the 211 streamgages analyzed for annual runoff. For the period of 1950 through 2011, the Ohio River provided almost one-half of the annual runoff at Vicksburg; the Missouri River contributed less than one-fourth, and the lower Mississippi River less than one-fourth. Those relative contribution patterns also occurred in 1973 and 2011, with the notable exception of the decrease in contribution of the lower Mississippi River tributaries and the increase in contribution from the upper Missouri River Basin in 2011 as compared to 1973 and the long-term average from 1950 to 2011.

  7. Medications at school: disposing of pharmaceutical waste.

    PubMed

    Taras, Howard; Haste, Nina M; Berry, Angela T; Tran, Jennifer; Singh, Renu F

    2014-03-01

    This project quantified and categorized medications left unclaimed by students at the end of the school year. It determined the feasibility of a model medication disposal program and assessed school nurses' perceptions of environmentally responsible medication disposal. At a large urban school district all unclaimed medications were collected at the end of a school year to determine the extent and nature of this problem. Nurses documented unclaimed medications and transported them to a central district location. An environmentally responsible medication disposal program, consisting of sealed containers bound for a local hospital's disposal system, was implemented. In a school district of approximately 133,000 students, there were 926 different medications abandoned at the end of a school year brought to a central disposal area. Nurses complied with the newly implemented protocol. Information collected from nurses indicates acceptance of the program. Disposal of unclaimed medications at a central location, use of secured containers, and transportation to a hospital for environmentally responsible disposal proved to be feasible and acceptable to the staff. Unclaimed medications at school each year pose a potentially huge environmental risk when disposed of improperly. It is feasible to implement an environmentally responsible medication disposal protocol at schools. © 2014, American School Health Association.

  8. Individual differences in algebraic cognition: Relation to the approximate number and semantic memory systems.

    PubMed

    Geary, David C; Hoard, Mary K; Nugent, Lara; Rouder, Jeffrey N

    2015-12-01

    The relation between performance on measures of algebraic cognition and acuity of the approximate number system (ANS) and memory for addition facts was assessed for 171 ninth graders (92 girls) while controlling for parental education, sex, reading achievement, speed of numeral processing, fluency of symbolic number processing, intelligence, and the central executive component of working memory. The algebraic tasks assessed accuracy in placing x,y pairs in the coordinate plane, speed and accuracy of expression evaluation, and schema memory for algebra equations. ANS acuity was related to accuracy of placements in the coordinate plane and expression evaluation but not to schema memory. Frequency of fact retrieval errors was related to schema memory but not to coordinate plane or expression evaluation accuracy. The results suggest that the ANS may contribute to or be influenced by spatial-numerical and numerical-only quantity judgments in algebraic contexts, whereas difficulties in committing addition facts to long-term memory may presage slow formation of memories for the basic structure of algebra equations. More generally, the results suggest that different brain and cognitive systems are engaged during the learning of different components of algebraic competence while controlling for demographic and domain general abilities. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Inter-layer synchronization in non-identical multi-layer networks

    NASA Astrophysics Data System (ADS)

    Leyva, I.; Sevilla-Escoboza, R.; Sendiña-Nadal, I.; Gutiérrez, R.; Buldú, J. M.; Boccaletti, S.

    2017-04-01

    Inter-layer synchronization is a dynamical process occurring in multi-layer networks composed of identical nodes. This process emerges when all layers are synchronized, while nodes in each layer do not necessarily evolve in unison. So far, the study of such inter-layer synchronization has been restricted to the case in which all layers have an identical connectivity structure. When layers are not identical, the inter-layer synchronous state is no longer a stable solution of the system. Nevertheless, when layers differ in just a few links, an approximate treatment is still feasible, and allows one to gather information on whether and how the system may wander around an inter-layer synchronous configuration. We report the details of an approximate analytical treatment for a two-layer multiplex, which results in the introduction of an extra inertial term accounting for structural differences. Numerical validation of the predictions highlights the usefulness of our approach, especially for small or moderate topological differences in the intra-layer coupling. Moreover, we identify a non-trivial relationship connecting the betweenness centrality of the missing links and the intra-layer coupling strength. Finally, by the use of multiplexed layers of electronic circuits, we study the inter-layer synchronization as a function of the removed links.

  10. MO-FG-CAMPUS-IeP2-01: Characterization of Beam Shaping Filters and Photon Spectra From HVL Profiles in CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bujila, R; Royal Institute of Technology, Stockholm; Kull, L

    Purpose: Advanced dosimetry in CT (e.g. the Monte Carlo method) requires an accurate characterization of the shaped filter and radiation quality used during a scan. The purpose of this work was to develop a method where half value layer (HVL) profiles along shaped filters could be made. From the HVL profiles the beam shaping properties and effective photon spectrum for a particular scan can be inferred. Methods: A measurement rig was developed to allow determinations of the HVL under a scatter-free narrow-beam geometry and constant focal spot to ionization chamber distance for different fan angles. For each fan angle themore » HVL is obtained by fitting the transmission of radiation through different thicknesses of an Al absorber (type 1100) using an appropriate model. The effective Al thickness of shaped filters and effective photon spectra are estimated using a model of photon emission from a Tungsten anode. This method is used to obtain the effective photon spectra and effective Al thickness of shaped filters for a CT scanner recently introduced to the market. Results: This study resulted in a set of effective photon spectra (central ray) for each kVp along with effective Al thicknesses of the different shaped filters. The effective photon spectra and effective Al thicknesses of shaped filters were used to obtain numerically approximated HVL profiles and compared to measured HVL profiles (mean absolute percentage error = 0.02). The central axis HVL found in the vendor’s technical documentation were compared to approximated HVL values (mean absolute percentage error = 0.03). Conclusion: This work has resulted in a unique method of measuring HVL profiles along shaped filters in CT. Further the effective photon spectra and the effective Al thicknesses of shaped filters that were obtained can be incorporated into Monte Carlo simulations.« less

  11. Apollo 16 spacecraft touches down in the central Pacific Ocean

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The Apollo 16 spacecraft touches down in the central Pacific Ocean at the end of its mission. Splashdown occurred at 1:45:06 p.m., Thursday, April 27, 1972 at coordinates of 00:45.2 degrees south latitude and 156:11.4 degrees west longitude, a point approximately 215 miles southeast of Christmas Island. All its parachutes are collapsing in the ocean around the Command Module.

  12. Geochronology Database for Central Colorado

    USGS Publications Warehouse

    Klein, T.L.; Evans, K.V.; deWitt, E.H.

    2010-01-01

    This database is a compilation of published and some unpublished isotopic and fission track age determinations in central Colorado. The compiled area extends from the southern Wyoming border to the northern New Mexico border and from approximately the longitude of Denver on the east to Gunnison on the west. Data for the tephrochronology of Pleistocene volcanic ash, carbon-14, Pb-alpha, common-lead, and U-Pb determinations on uranium ore minerals have been excluded.

  13. Environmental assessment for the proposed effluent limitations guidelines, pretreatment standards, and new source performance standards for the centralized waste treatment industry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-12-01

    This report assesses the water quality related benefits that would be expected if the US Environmental Protection Agency (EPA) adopts the proposed effluent limitations, guidelines and pretreatment standards for the Centralized Waste Treatment (CWT) Industry. EPA estimates that under baseline conditions 205 CWT facilities discharge approximately 5.22 million lbs/year of metal and organic pollutants.

  14. Interpretation of fault-controlled ramp structures in sedimentary basins - example from Caspian Sea using Landsat TM data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Iranpanah, A.

    1989-03-01

    Lineaments on a series of edge-enhanced images (TM data) from a region around the Caspian Sea form a geomorphically significant linear trend along the major Caucasus-Kopeh Dagh fault line. This fault represents the line of collision between the Cimmerian continents and the Turan plate on the south and north, respectively. The lineament zone manifests a ramp structure that forms a relatively narrow topographic high in the Caspian Sea. Paleogeographic studies of the Caspian Sea suggest that the basin is part of the eastern Paratethys, which began to develop in the early Paleogene during the Alpine-Himalayan uplift. On the basis ofmore » the lineaments and associated geomorphic features, the Caspian Sea can be divided into southern, central, and the northern Caspian subbasins. The Caucasus-Kopeh Dagh fault line trends N80/degrees/W and separates the southern Caspian from the central subbasin, approximately along 40/degrees/N latitude. The boundary between the central and the northern subbasins is also a linear topographic high which trends N70/degrees/E and lies approximately at 44/degrees/N latitude. The southern and central subbasins have subequal areal extension covering 35.64% and the 36.63% of the whole sea, whereas the northern subbasin occupies only 27.73% of the basin.« less

  15. Discrete breathers for a discrete nonlinear Schrödinger ring coupled to a central site.

    PubMed

    Jason, Peter; Johansson, Magnus

    2016-01-01

    We examine the existence and properties of certain discrete breathers for a discrete nonlinear Schrödinger model where all but one site are placed in a ring and coupled to the additional central site. The discrete breathers we focus on are stationary solutions mainly localized on one or a few of the ring sites and possibly also the central site. By numerical methods, we trace out and study the continuous families the discrete breathers belong to. Our main result is the discovery of a split bifurcation at a critical value of the coupling between neighboring ring sites. Below this critical value, families form closed loops in a certain parameter space, implying that discrete breathers with and without central-site occupation belong to the same family. Above the split bifurcation the families split up into several separate ones, which bifurcate with solutions with constant ring amplitudes. For symmetry reasons, the families have different properties below the split bifurcation for even and odd numbers of sites. It is also determined under which conditions the discrete breathers are linearly stable. The dynamics of some simpler initial conditions that approximate the discrete breathers are also studied and the parameter regimes where the dynamics remain localized close to the initially excited ring site are related to the linear stability of the exact discrete breathers.

  16. Organizational capacity for chronic disease prevention: a survey of Canadian public health organizations.

    PubMed

    Hanusaik, Nancy; O'Loughlin, Jennifer L; Kishchuk, Natalie; Paradis, Gilles; Cameron, Roy

    2010-04-01

    There are no national data on levels of organizational capacity within the Canadian public health system to reduce the burden of chronic disease. Cross-sectional data were collected in a national survey (October 2004 to April 2005) of all 216 national, provincial and regional-level organizations engaged in chronic disease prevention through primary prevention or healthy lifestyle promotion. Levels of organizational capacity (defined as skills and resources to implement chronic disease prevention programmes), potential determinants of organizational capacity and involvement in chronic disease prevention programming were compared in western, central and eastern Canada and across three types of organizations (formal public health organizations, non-governmental organizations and grouped organizations). Forty percent of organizations were located in Central Canada. Approximately 50% were formal public health organizations. Levels of skill and involvement were highest for activities that addressed tobacco control and healthy eating; lowest for stress management, social determinants of health and programme evaluation. The few notable differences in skill levels by provincial grouping favoured Central Canada. Resource adequacy was rated low across the country; but was lowest in eastern Canada and among formal public health organizations. Determinants of organizational capacity (organizational supports and partnerships) were highest in central Canada and among grouped organizations. These data provide an evidence base to identify strengths and gaps in organizational capacity and involvement in chronic disease prevention programming in the organizations that comprise the Canadian public health system.

  17. Central corneal thickness in children.

    PubMed

    Bradfield, Yasmin S; Melia, B Michele; Repka, Michael X; Kaminski, Brett M; Davitt, Bradley V; Johnson, David A; Kraker, Raymond T; Manny, Ruth E; Matta, Noelle S; Weise, Katherine K; Schloff, Susan

    2011-09-01

    To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age and to determine whether CCT varies by age, race, or ethnicity. Prospective observational multicenter study. Central corneal thickness was measured with a handheld contact pachymeter. A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P < .001 for both) by approximately 20 μm. Thicker median CCT was observed with each successive year of age from age 1 to 11 years, with year-to-year differences steadily decreasing and reaching a plateau after age 11 at 573 μm in white and Hispanic children and 551 μm in African American children. For every 100 μm of thicker CCT measured, the intraocular pressure was 1.5 mm Hg higher on average (P < .001). For every diopter of increased myopic refractive error, CCT was 1 μm thinner on average (P < .001). Median CCT increases with age from 1 to 11 years, with the greatest increase present in the youngest age groups. African American children on average have thinner central corneas than white and Hispanic children, whereas white and Hispanic children demonstrate similar CCT.

  18. Shear and compression buckling analysis for anisotropic panels with centrally located elliptical cutouts

    NASA Technical Reports Server (NTRS)

    Britt, V. O.

    1993-01-01

    An approximate analysis for buckling of biaxial- and shear-loaded anisotropic panels with centrally located elliptical cutouts is presented in the present paper. The analysis is composed of two parts, a prebuckling analysis and a buckling analysis. The prebuckling solution is determined using Lekhnitskii's complex variable equations of plane elastostatics combined with a Laurent series approximation and a boundary collocation method. The buckling solution is obtained using the principle of minimum potential energy. A by-product of the minimum potential energy equation is an integral equation which is solved using Gaussian quadrature. Comparisons with documented experimental results and finite element analyses indicate that the approximate analysis accurately predicts the buckling loads of square biaxial- and shear-loaded panels having elliptical cutouts with major axes up to sixty percent of the panel width. Results of a parametric study are presented for shear- and compression-loaded rectangular anisotropic panels with elliptical cutouts. The effects of panel aspect ratio, cutout shape, cutout size, cutout orientation, laminate anisotropy, and combined loading on the buckling load are examined.

  19. Tsunami hazard assessment in El Salvador, Central America, from seismic sources through flooding numerical models

    NASA Astrophysics Data System (ADS)

    Álvarez-Gómez, J. A.; Aniel-Quiroga, Í.; Gutiérrez-Gutiérrez, O. Q.; Larreynaga, J.; González, M.; Castro, M.; Gavidia, F.; Aguirre-Ayerbe, I.; González-Riancho, P.; Carreño, E.

    2013-05-01

    El Salvador is the smallest and most densely populated country in Central America; its coast has approximately a length of 320 km, 29 municipalities and more than 700 000 inhabitants. In El Salvador there have been 15 recorded tsunamis between 1859 and 2012, 3 of them causing damages and hundreds of victims. The hazard assessment is commonly based on propagation numerical models for earthquake-generated tsunamis and can be approached from both Probabilistic and Deterministic Methods. A deterministic approximation has been applied in this study as it provides essential information for coastal planning and management. The objective of the research was twofold, on the one hand the characterization of the threat over the entire coast of El Salvador, and on the other the computation of flooding maps for the three main localities of the Salvadorian coast. For the latter we developed high resolution flooding models. For the former, due to the extension of the coastal area, we computed maximum elevation maps and from the elevation in the near-shore we computed an estimation of the run-up and the flooded area using empirical relations. We have considered local sources located in the Middle America Trench, characterized seismotectonically, and distant sources in the rest of Pacific basin, using historical and recent earthquakes and tsunamis. We used a hybrid finite differences - finite volumes numerical model in this work, based on the Linear and Non-linear Shallow Water Equations, to simulate a total of 24 earthquake generated tsunami scenarios. In the western Salvadorian coast, run-up values higher than 5 m are common, while in the eastern area, approximately from La Libertad to the Gulf of Fonseca, the run-up values are lower. The more exposed areas to flooding are the lowlands in the Lempa River delta and the Barra de Santiago Western Plains. The results of the empirical approximation used for the whole country are similar to the results obtained with the high resolution numerical modelling, being a good and fast approximation to obtain preliminary tsunami hazard estimations. In Acajutla and La Libertad, both important tourism centres being actively developed, flooding depths between 2 and 4 m are frequent, accompanied with high and very high person instability hazard. Inside the Gulf of Fonseca the impact of the waves is almost negligible.

  20. Tsunami hazard assessment in El Salvador, Central America, from seismic sources through flooding numerical models.

    NASA Astrophysics Data System (ADS)

    Álvarez-Gómez, J. A.; Aniel-Quiroga, Í.; Gutiérrez-Gutiérrez, O. Q.; Larreynaga, J.; González, M.; Castro, M.; Gavidia, F.; Aguirre-Ayerbe, I.; González-Riancho, P.; Carreño, E.

    2013-11-01

    El Salvador is the smallest and most densely populated country in Central America; its coast has an approximate length of 320 km, 29 municipalities and more than 700 000 inhabitants. In El Salvador there were 15 recorded tsunamis between 1859 and 2012, 3 of them causing damages and resulting in hundreds of victims. Hazard assessment is commonly based on propagation numerical models for earthquake-generated tsunamis and can be approached through both probabilistic and deterministic methods. A deterministic approximation has been applied in this study as it provides essential information for coastal planning and management. The objective of the research was twofold: on the one hand the characterization of the threat over the entire coast of El Salvador, and on the other the computation of flooding maps for the three main localities of the Salvadorian coast. For the latter we developed high-resolution flooding models. For the former, due to the extension of the coastal area, we computed maximum elevation maps, and from the elevation in the near shore we computed an estimation of the run-up and the flooded area using empirical relations. We have considered local sources located in the Middle America Trench, characterized seismotectonically, and distant sources in the rest of Pacific Basin, using historical and recent earthquakes and tsunamis. We used a hybrid finite differences-finite volumes numerical model in this work, based on the linear and non-linear shallow water equations, to simulate a total of 24 earthquake-generated tsunami scenarios. Our results show that at the western Salvadorian coast, run-up values higher than 5 m are common, while in the eastern area, approximately from La Libertad to the Gulf of Fonseca, the run-up values are lower. The more exposed areas to flooding are the lowlands in the Lempa River delta and the Barra de Santiago Western Plains. The results of the empirical approximation used for the whole country are similar to the results obtained with the high-resolution numerical modelling, being a good and fast approximation to obtain preliminary tsunami hazard estimations. In Acajutla and La Libertad, both important tourism centres being actively developed, flooding depths between 2 and 4 m are frequent, accompanied with high and very high person instability hazard. Inside the Gulf of Fonseca the impact of the waves is almost negligible.

  1. Evidence for Intermediate Polars as the Origin of the Galactic Center Hard X-Ray Emission

    NASA Technical Reports Server (NTRS)

    Hailey, Charles J.; Mori, Kaya; Perez, Kerstin; Canipe, Alicia M.; Hong, Jaesub; Tomsick, John A.; Boggs, Steven E.; Christensen, Finn E.; Craig, William W.; Fornasini, Francesa; hide

    2016-01-01

    Recently, unresolved hard (20-40 keV) X-ray emission has been discovered within the central 10 pc of the Galaxy, possibly indicating a large population of intermediate polars (IPs). Chandra and XMM-Newton measurements in the surrounding approximately 50 pc imply a much lighter population of IPs with (M(sub WD)) approximately 0.5 solar mass. Here we use broadband NuSTAR observations of two IPs: TV Columbae, which has a fairly typical but widely varying reported mass of (M(sub WD)) approximately 0.5-1.0 solar mass, and IGR J17303-0601, with a heavy reported mass of (M(sub WD)) approximately 1.0-1.2 solar mass. We investigate how varying spectral models and observed energy ranges influences estimated white dwarf mass. Observations of the inner 10 pc can be accounted for by IPs with (M(sub WD) approximately 0.9 solar mass, consistent with that of the CV population in general and the X-ray observed field IPs in particular. The lower mass derived by Chandra and XMM-Newton appears to be an artifact of narrow energy-band fitting. To explain the (unresolved) central hard X-ray emission (CHXE) by IPs requires an X-ray (2-8 keV) luminosity function (XLF) extending down to at least 5 x 10(exp 31) per erg s. The CHXE XLF, if extended to the surrounding approximately 50 pc observed by Chandra and XMM-Newton, requires that at least approximately 20%-40% of the approximately 9000 point sources are IPs. If the XLF extends just a factor of a few lower in luminosity, then the vast majority of these sources are IPs. This is in contrast to recent observations of the Galactic ridge, where the bulk of the 2-8 keV emission is ascribed to non-magnetic CVs.

  2. Charged-particle pseudorapidity distributions in Au+Au collisions at sNN=62.4 GeV

    NASA Astrophysics Data System (ADS)

    Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; Nieuwenhuizen, G. J. Van; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wysłouch, B.

    2006-08-01

    The charged-particle pseudorapidity density for Au+Au collisions at sNN=62.4 GeV has been measured over a wide range of impact parameters and compared to results obtained at other energies. As a function of collision energy, the pseudorapidity distribution grows systematically both in height and width. The midrapidity density is found to grow approximately logarithmically between BNL Alternating Gradient Synchrotron (AGS) energies and the top BNL Relativistic Heavy Ion Collider (RHIC) energy. There is also an approximate factorization of the centrality and energy dependence of the midrapidity yields. The new results at sNN=62.4 GeV confirm the previously observed phenomenon of “extended longitudinal scaling” in the pseudorapidity distributions when viewed in the rest frame of one of the colliding nuclei. It is also found that the evolution of the shape of the distribution with centrality is energy independent, when viewed in this reference frame. As a function of centrality, the total charged particle multiplicity scales linearly with the number of participant pairs as it was observed at other energies.

  3. Spatial interaction between tissue pressure and skeletal muscle perfusion during contraction.

    PubMed

    van Donkelaar, C C; Huyghe, J M; Vankan, W J; Drost, M R

    2001-05-01

    The vascular waterfall theory attributes decreased muscle perfusion during contraction to increased intramuscular pressure (P(IM)) and concomitant increase in venous resistance. Although P(IM) is distributed during contractions, this theory does not account for heterogeneity. This study hypothesises that pressure heterogeneity could affect the interaction between P(IM) rise and perfusion. Regional tissue perfusion during submaximum (100kPa) tetanic contraction is studied, using a finite element model of perfused contracting skeletal muscle. Capillary flow in muscles with one proximal artery and vein (SIM(1)) and with an additional distal artery and vein (SIM(2)) is compared. Blood flow and pressures at rest and P(IM) during contraction ( approximately 25kPa maximally) are similar between simulations, but capillary flow and venous pressure differ. In SIM(2), venous pressure and capillary flow correspond to P(IM) distribution, whereas capillary flow in SIM(1) is less than 10% of flow in SIM(2), in the muscle half without draining vein. This difference is caused by a high central P(IM), followed by central venous pressure rise, in agreement with the waterfall theory. The high central pressure (SIM(1)), obstructs outflow from the distal veins. Distal venous pressure rises until central blood pressure is reached, although local P(IM) is low. Adding a distal vein (SIM(2)) restores the perfusion. It is concluded that regional effects contribute to the interaction between P(IM) and perfusion during contraction. Unlike stated by the vascular waterfall theory, venous pressure may locally exceed P(IM). Although this can be explained by the principles of this theory, the theory does not include this phenomenon as such.

  4. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.

    PubMed

    Buchmueller, Karen L; Staples, Andrew M; Howard, Cameron M; Horick, Sarah M; Uthe, Peter B; Le, N Minh; Cox, Kari K; Nguyen, Binh; Pacheco, Kimberly A O; Wilson, W David; Lee, Moses

    2005-01-19

    Pyrrole (Py) and imidazole (Im) polyamides can be designed to target specific DNA sequences. The effect that the pyrrole and imidazole arrangement, plus DNA sequence, have on sequence specificity and binding affinity has been investigated using DNA melting (DeltaT(M)), circular dichroism (CD), and surface plasmon resonance (SPR) studies. SPR results obtained from a complete set of triheterocyclic polyamides show a dramatic difference in the affinity of f-ImPyIm for its cognate DNA (K(eq) = 1.9 x 10(8) M(-1)) and f-PyPyIm for its cognate DNA (K(eq) = 5.9 x 10(5) M(-1)), which could not have been anticipated prior to characterization of these compounds. Moreover, f-ImPyIm has a 10-fold greater affinity for CGCG than distamycin A has for its cognate, AATT. To understand this difference, the triamide dimers are divided into two structural groupings: central and terminal pairings. The four possible central pairings show decreasing selectivity and affinity for their respective cognate sequences: -ImPy > -PyPy- > -PyIm- approximately -ImIm-. These results extend the language of current design motifs for polyamide sequence recognition to include the use of "words" for recognizing two adjacent base pairs, rather than "letters" for binding to single base pairs. Thus, polyamides designed to target Watson-Crick base pairs should utilize the strength of -ImPy- and -PyPy- central pairings. The f/Im and f/Py terminal groups yielded no advantage for their respective C/G or T/A base pairs. The exception is with the -ImPy- central pairing, for which f/Im has a 10-fold greater affinity for C/G than f/Py has for T/A.

  5. Examining Racial and Ethnic Differences in Nursing Home Quality.

    PubMed

    Hefele, Jennifer Gaudet; Ritter, Grant A; Bishop, Christine E; Acevedo, Andrea; Ramos, Candi; Nsiah-Jefferson, Laurie A; Katz, Gabrielle

    2017-11-01

    Identifying racial/ethnic differences in quality is central to identifying, monitoring, and reducing disparities. Although disparities across all individual nursing home residents and disparities associated with between-nursing home differences have been established, little is known about the degree to which quality of care varies by race//ethnicity within nursing homes. A study was conducted to measure within-facility differences for a range of publicly reported nursing home quality measures. Resident assessment data on approximately 15,000 nursing homes and approximately 3 million residents (2009) were used to assess eight commonly used and publicly reported long-stay quality measures: the proportion of residents with weight loss, with high-risk and low-risk pressure ulcers, with incontinence, with depressive symptoms, in restraints daily, and who experienced a urinary tract infection or functional decline. Each measure was stratified by resident race/ethnicity (non-Hispanic white, non-Hispanic black, and Hispanic), and within-facility differences were examined. Small but significant differences in care on average were found, often in an unexpected direction; in many cases, white residents were experiencing poorer outcomes than black and Hispanic residents in the same facility. However, a broad range of differences in care by race/ethnicity within nursing homes was also found. The results suggest that care is delivered equally across all racial/ethnic groups in the same nursing home, on average. The results support the call for publicly reporting stratified nursing home quality measures and suggest that nursing home providers should attempt to identify racial/ethnic within-facility differences in care. Copyright © 2017 The Joint Commission. Published by Elsevier Inc. All rights reserved.

  6. Exact Riemann solutions of the Ripa model for flat and non-flat bottom topographies

    NASA Astrophysics Data System (ADS)

    Rehman, Asad; Ali, Ishtiaq; Qamar, Shamsul

    2018-03-01

    This article is concerned with the derivation of exact Riemann solutions for Ripa model considering flat and non-flat bottom topographies. The Ripa model is a system of shallow water equations accounting for horizontal temperature gradients. In the case of non-flat bottom topography, the mass, momentum and energy conservation principles are utilized to relate the left and right states across the step-type bottom topography. The resulting system of algebraic equations is solved iteratively. Different numerical case studies of physical interest are considered. The solutions obtained from developed exact Riemann solvers are compared with the approximate solutions of central upwind scheme.

  7. Young dispersal of xerophil Nitraria lineages in intercontinental disjunctions of the Old World

    PubMed Central

    Zhang, Ming-Li; Temirbayeva, Kamshat; Sanderson, Stewart C.; Chen, Xi

    2015-01-01

    Many cases of intercontinental disjunct distributions of seed plants have been investigated, however few have concerned the continents of Eurasia (mainly Central Asia), Africa, and Australia, especially the xerophytic lineages are lacking. Nitraria (Nitrariaceae) is just one of these xerophytic lineages. Previous Nitraria studies have hypothesized either Africa as the ancient center, with dispersals to Australia and Eurasia, or alternatively Central Asia, due to a concentration of endemism and diversity there. Our findings show eastern Central Asia, i.e. the eastern Tethys, to be the correct place of origin. Dispersal westward to Africa occurred during the late Oligocene to Pliocene, whereas dispersal to Australia from western Central Asia was young since Pliocene 2.61 Ma. Two related tetraploids are indicated to have diversified in eastern Central Asia at approximately 5.89 Ma, while the Australian tetraploid N. billardieri, is an independently derived, recent dispersal from western Central Asia. PMID:26343223

  8. Hafnium isotope stratigraphy of ferromanganese crusts

    PubMed

    Lee; Halliday; Hein; Burton; Christensen; Gunther

    1999-08-13

    A Cenozoic record of hafnium isotopic compositions of central Pacific deep water has been obtained from two ferromanganese crusts. The crusts are separated by more than 3000 kilometers but display similar secular variations. Significant fluctuations in hafnium isotopic composition occurred in the Eocene and Oligocene, possibly related to direct advection from the Indian and Atlantic oceans. Hafnium isotopic compositions have remained approximately uniform for the past 20 million years, probably reflecting increased isolation of the central Pacific. The mechanisms responsible for the increase in (87)Sr/(86)Sr in seawater through the Cenozoic apparently had no effect on central Pacific deep-water hafnium.

  9. Ash Shutbah: A possible impact structure in Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Gnos, Edwin; Hofmann, Beda A.; Schmieder, Martin; Al-Wagdani, Khalid; Mahjoub, Ayman; Al-Solami, Abdulaziz A.; Habibullah, Siddiq N.; Matter, Albert; Alwmark, Carl

    2014-10-01

    We have investigated the Ash Shutbah circular structure in central Saudi Arabia (21°37'N 45°39'E) using satellite imagery, field mapping, thin-section petrography, and X-ray diffraction of collected samples. The approximately 2.1 km sized structure located in flat-lying Jurassic Tuwaiq Mountain Limestone has been nearly peneplained by erosional processes. Satellite and structural data show a central area consisting of Dhruma Formation sandstones with steep bedding and tight folds plunging radially outward. Open folding occurs in displaced, younger Tuwaiq Mountain Limestone Formation blocks surrounding the central area, but is absent outside the circular structure. An approximately 60 cm thick, unique folded and disrupted orthoquartzitic sandstone marker bed occurring in the central area of the structure is found 140 m deeper in undisturbed escarpment outcrops located a few hundred meters west of the structure. With exception of a possible concave shatter cone found in the orthoquartzite of the central area, other diagnostic shock features are lacking. Some quartz-rich sandstones from the central area show pervasive fracturing of quartz grains with common concussion fractures. This deformation was followed by an event of quartz dissolution and calcite precipitation consistent with local sea- or groundwater heating. The combination of central stratigraphic uplift of 140 m, concussion features in discolored sandstone, outward-dipping concentric folds in the central area, deformation restricted to the rocks of the ring structure, a complex circular structure of 2.1 km diameter that appears broadly consistent with what one would expect from an impact structure in sedimentary targets, and a possible shatter cone all point to an impact origin of the Ash Shutbah structure. In fact, the Ash Shutbah structure appears to be a textbook example of an eroded, complex impact crater located in flat-lying sedimentary rocks, where the undisturbed stratigraphic section can be studied in escarpment outcrops in the vicinity of the structure.

  10. 78 FR 48766 - Petition for Waiver of Compliance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ...'s Network Management Center in Montreal, QC, Canada. CP operates approximately six to eight trains a day over this segment. The trackage is operated under a Centralized Traffic Control system and...

  11. Utilization of advanced calibration techniques in stochastic rock fall analysis of quarry slopes

    NASA Astrophysics Data System (ADS)

    Preh, Alexander; Ahmadabadi, Morteza; Kolenprat, Bernd

    2016-04-01

    In order to study rock fall dynamics, a research project was conducted by the Vienna University of Technology and the Austrian Central Labour Inspectorate (Federal Ministry of Labour, Social Affairs and Consumer Protection). A part of this project included 277 full-scale drop tests at three different quarries in Austria and recording key parameters of the rock fall trajectories. The tests involved a total of 277 boulders ranging from 0.18 to 1.8 m in diameter and from 0.009 to 8.1 Mg in mass. The geology of these sites included strong rock belonging to igneous, metamorphic and volcanic types. In this paper the results of the tests are used for calibration and validation a new stochastic computer model. It is demonstrated that the error of the model (i.e. the difference between observed and simulated results) has a lognormal distribution. Selecting two parameters, advanced calibration techniques including Markov Chain Monte Carlo Technique, Maximum Likelihood and Root Mean Square Error (RMSE) are utilized to minimize the error. Validation of the model based on the cross validation technique reveals that in general, reasonable stochastic approximations of the rock fall trajectories are obtained in all dimensions, including runout, bounce heights and velocities. The approximations are compared to the measured data in terms of median, 95% and maximum values. The results of the comparisons indicate that approximate first-order predictions, using a single set of input parameters, are possible and can be used to aid practical hazard and risk assessment.

  12. Global structure of magnetorotationally turbulent protoplanetary discs

    NASA Astrophysics Data System (ADS)

    Flaig, M.; Ruoff, Patrick; Kley, W.; Kissmann, R.

    2012-03-01

    The aim of this paper is to investigate the spatial structure of a protoplanetary disc whose dynamics is governed by magnetorotational turbulence. We perform a series of local three-dimensional chemoradiative magnetohydrodynamic simulations located at different radii of a disc which is twice as massive as the standard minimum mass solar nebula of Hayashi. The ionization state of the disc is calculated by including collisional ionization, stellar X-rays, cosmic rays and the decay of radionuclides as ionization sources, and by solving a simplified chemical network which includes the effect of the absorption of free charges by μm-sized dust grains. In the region where the ionization is too low to ensure good coupling between matter and magnetic fields, a non-turbulent central 'dead zone' forms, which ranges approximately from a distance of 2 to 4 au from the central star. The approach taken in this work allows for the first time to derive the global spatial structure of a protoplanetary disc from a set of physically realistic numerical simulations.

  13. One year of migration data for a western yellow-billed cuckoo

    USGS Publications Warehouse

    Sechrist, Juddson D.; Paxton, Eben H.; Ahlers, Darrell D.; Doster, Robert H.; Ryan, Vicky M.

    2012-01-01

    In 2009, we studied the migration of the Western Yellow-billed Cuckoo by capturing 13 breeding birds on the middle Rio Grande, New Mexico, and attaching a 1.5-g Mk 14-S British Antarctic Survey geolocator to each bird. In 2010, we recaptured one of the cuckoos, enabling us to download its geolocation data. The cuckoo had flown approximately 9500 km during its southward migration, traveling through Central America to winter in portions of Bolivia, Brazil, Paraguay, and Argentina. The spring migration route differed somewhat from the fall route, with the cuckoo bypassing Central America to migrate through the Caribbean. Additionally, it moved between New Mexico and Mexico at the end of summer in 2009 and again in 2010 before being recaptured at its breeding site. Our results, albeit from one individual, hint at a dynamic migration strategy and have broad implications for the ecology and conservation of the Western Yellow-billed Cuckoo, a species of conservation concern.

  14. Partonic Flow and phi-Meson production in Au+Au collisions at sqrt radical sNN = 200 GeV.

    PubMed

    Abelev, B I; Aggarwal, M M; Ahammed, Z; Anderson, B D; Arkhipkin, D; Averichev, G S; Bai, Y; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Baumgart, S; Belaga, V V; Bellingeri-Laurikainen, A; Bellwied, R; Benedosso, F; Betts, R R; Bhardwaj, S; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Blyth, S-L; Bombara, M; Bonner, B E; Botje, M; Bouchet, J; Brandin, A V; Bravar, A; Burton, T P; Bystersky, M; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Callner, J; Catu, O; Cebra, D; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Chung, S U; Coffin, J P; Cormier, T M; Cosentino, M R; Cramer, J G; Crawford, H J; Das, D; Dash, S; Daugherity, M; de Moura, M M; Dedovich, T G; DePhillips, M; Derevschikov, A A; Didenko, L; Dietel, T; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Du, F; Dunin, V B; Dunlop, J C; Dutta Mazumdar, M R; Eckardt, V; Edwards, W R; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Fatemi, R; Fedorisin, J; Feng, A; Filip, P; Finch, E; Fine, V; Fisyak, Y; Fu, J; Gagliardi, C A; Gaillard, L; Ganti, M S; Garcia-Solis, E; Ghazikhanian, V; Ghosh, P; Gorbunov, Y G; Gos, H; Grebenyuk, O; Grosnick, D; Grube, B; Guertin, S M; Guimaraes, K S F F; Gupta, N; Haag, B; Hallman, T J; Hamed, A; Harris, J W; He, W; Heinz, M; Henry, T W; Heppelmann, S; Hippolyte, B; Hirsch, A; Hjort, E; Hoffman, A M; Hoffmann, G W; Hofman, D J; Hollis, R S; Horner, M J; Huang, H Z; Hughes, E W; Humanic, T J; Igo, G; Iordanova, A; Jacobs, P; Jacobs, W W; Jakl, P; Jia, F; Jones, P G; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kaplan, M; Keane, D; Kechechyan, A; Kettler, D; Khodyrev, V Yu; Kim, B C; Kiryluk, J; Kisiel, A; Kislov, E M; Klein, S R; Knospe, A G; Kocoloski, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kouchpil, V; Kowalik, K L; Kravtsov, P; Kravtsov, V I; Krueger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kurnadi, P; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; LaPointe, S; Laue, F; Lauret, J; Lebedev, A; Lednicky, R; Lee, C-H; Lehocka, S; LeVine, M J; Li, C; Li, Q; Li, Y; Lin, G; Lin, X; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, H; Liu, J; Liu, L; Ljubicic, T; Llope, W J; Longacre, R S; Love, W A; Lu, Y; Ludlam, T; Lynn, D; Ma, G L; Ma, J G; Ma, Y G; Mahapatra, D P; Majka, R; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Martin, L; Matis, H S; Matulenko, Yu A; McClain, C J; McShane, T S; Melnick, Yu; Meschanin, A; Millane, J; Miller, M L; Minaev, N G; Mioduszewski, S; Mironov, C; Mischke, A; Mitchell, J; Mohanty, B; Morozov, D A; Munhoz, M G; Nandi, B K; Nattrass, C; Nayak, T K; Nelson, J M; Nepali, C; Netrakanti, P K; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Pachr, M; Pal, S K; Panebratsev, Y; Pavlinov, A I; Pawlak, T; Peitzmann, T; Perevoztchikov, V; Perkins, C; Peryt, W; Phatak, S C; Planinic, M; Pluta, J; Poljak, N; Porile, N; Poskanzer, A M; Potekhin, M; Potrebenikova, E; Potukuchi, B V K S; Prindle, D; Pruneau, C; Putschke, J; Qattan, I A; Raniwala, R; Raniwala, S; Ray, R L; Relyea, D; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Rose, A; Roy, C; Ruan, L; Russcher, M J; Sahoo, R; Sakrejda, I; Sakuma, T; Salur, S; Sandweiss, J; Sarsour, M; Sazhin, P S; Schambach, J; Scharenberg, R P; Schmitz, N; Seger, J; Selyuzhenkov, I; Seyboth, P; Shabetai, A; Shahaliev, E; Shao, M; Sharma, M; Shen, W Q; Shimanskiy, S S; Sichtermann, E P; Simon, F; Singaraju, R N; Smirnov, N; Snellings, R; Sorensen, P; Sowinski, J; Speltz, J; Spinka, H M; Srivastava, B; Stadnik, A; Stanislaus, T D S; Staszak, D; Stock, R; Strikhanov, M; Stringfellow, B; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Z; Surrow, B; Symons, T J M; Szanto de Toledo, A; Takahashi, J; Tang, A H; Tarnowsky, T; Thomas, J H; Timmins, A R; Timoshenko, S; Tokarev, M; Trainor, T A; Trentalange, S; Tribble, R E; Tsai, O D; Ulery, J; Ullrich, T; Underwood, D G; Van Buren, G; van der Kolk, N; van Leeuwen, M; Vander Molen, A M; Varma, R; Vasilevski, I M; Vasiliev, A N; Vernet, R; Vigdor, S E; Viyogi, Y P; Vokal, S; Voloshin, S A; Waggoner, W T; Wang, F; Wang, G; Wang, J S; Wang, X L; Wang, Y; Watson, J W; Webb, J C; Westfall, G D; Wetzler, A; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wu, J; Wu, Y; Xu, N; Xu, Q H; Xu, Z; Yepes, P; Yoo, I-K; Yue, Q; Yurevich, V I; Zhan, W; Zhang, H; Zhang, W M; Zhang, Y; Zhang, Z P; Zhao, Y; Zhong, C; Zhou, J; Zoulkarneev, R; Zoulkarneeva, Y; Zubarev, A N; Zuo, J X

    2007-09-14

    We present first measurements of the phi-meson elliptic flow (v2(pT)) and high-statistics pT distributions for different centralities from radical sNN=200 GeV Au+Au collisions at RHIC. In minimum bias collisions the v2 of the phi meson is consistent with the trend observed for mesons. The ratio of the yields of the Omega to those of the phi as a function of transverse momentum is consistent with a model based on the recombination of thermal s quarks up to pT approximately 4 GeV/c, but disagrees at higher momenta. The nuclear modification factor (R CP) of phi follows the trend observed in the K S 0 mesons rather than in Lambda baryons, supporting baryon-meson scaling. These data are consistent with phi mesons in central Au+Au collisions being created via coalescence of thermalized s quarks and the formation of a hot and dense matter with partonic collectivity at RHIC.

  15. The landscape of particle production: results from PHOBOS

    NASA Astrophysics Data System (ADS)

    Steinberg, Peter; PHOBOS Collaboration; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Becker, B.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Decowski, M. P.; García, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Harrington, A. S.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lee, J. W.; Lin, W. T.; Manly, S.; McLeod, D.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Sedykh, I.; Skulski, W.; Smith, C. E.; Stephans, G. S. F.; Sukhanov, A.; Tang, J.-L.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Verdier, R.; Veres, G. I.; Wolfs, F. L. H.; Wosiek, B.; Wozniak, K.; Wuosmaa, A. H.; Wysłouch, B.; Zhang, J.

    2004-08-01

    Recent results from the PHOBOS experiment at RHIC are presented, both from Au+Au collisions from the 2001 run and p+p and d+Au collisions from 2003. The centrality dependence of the total charged-particle multiplicity in p+p and d+Au shows features, such as Npart scaling and limiting fragmentation, similar to p+A collisions at lower energies. Multiparticle physics in Au+Au is found to be local in (pseudo)rapidity, both when observed by HBT correlations and by forward-backward pseudorapidity correlations. The shape of elliptic flow in Au+Au, measured over the full range of pseudorapidity, appears to have a very weak centrality dependence. Identified particle ratios in d+Au reactions show little difference between the shape of proton and anti-proton spectra, while the absolute yields show an approximate mT scaling. Finally, results on RdAu as a function of pseudorapidity show that this ratio decreases monotonically with η, even between 0.2 < η < 1.4.

  16. Measuring the glycemic index of foods: interlaboratory study.

    PubMed

    Wolever, Thomas M S; Brand-Miller, Jennie C; Abernethy, John; Astrup, Arne; Atkinson, Fiona; Axelsen, Mette; Björck, Inger; Brighenti, Furio; Brown, Rachel; Brynes, Audrey; Casiraghi, M Cristina; Cazaubiel, Murielle; Dahlqvist, Linda; Delport, Elizabeth; Denyer, Gareth S; Erba, Daniela; Frost, Gary; Granfeldt, Yvonne; Hampton, Shelagh; Hart, Valerie A; Hätönen, Katja A; Henry, C Jeya; Hertzler, Steve; Hull, Sarah; Jerling, Johann; Johnston, Kelly L; Lightowler, Helen; Mann, Neil; Morgan, Linda; Panlasigui, Leonora N; Pelkman, Christine; Perry, Tracy; Pfeiffer, Andreas F H; Pieters, Marlien; Ramdath, D Dan; Ramsingh, Rayna T; Robert, S Daniel; Robinson, Carol; Sarkkinen, Essi; Scazzina, Francesca; Sison, Dave Clark D; Sloth, Birgitte; Staniforth, Jane; Tapola, Niina; Valsta, Liisa M; Verkooijen, Inge; Weickert, Martin O; Weseler, Antje R; Wilkie, Paul; Zhang, Jian

    2008-01-01

    Many laboratories offer glycemic index (GI) services. We assessed the performance of the method used to measure GI. The GI of cheese-puffs and fruit-leather (centrally provided) was measured in 28 laboratories (n=311 subjects) by using the FAO/WHO method. The laboratories reported the results of their calculations and sent the raw data for recalculation centrally. Values for the incremental area under the curve (AUC) reported by 54% of the laboratories differed from central calculations. Because of this and other differences in data analysis, 19% of reported food GI values differed by >5 units from those calculated centrally. GI values in individual subjects were unrelated to age, sex, ethnicity, body mass index, or AUC but were negatively related to within-individual variation (P=0.033) expressed as the CV of the AUC for repeated reference food tests (refCV). The between-laboratory GI values (mean+/-SD) for cheese-puffs and fruit-leather were 74.3+/-10.5 and 33.2+/-7.2, respectively. The mean laboratory GI was related to refCV (P=0.003) and the type of restrictions on alcohol consumption before the test (P=0.006, r2=0.509 for model). The within-laboratory SD of GI was related to refCV (P<0.001), the glucose analysis method (P=0.010), whether glucose measures were duplicated (P=0.008), and restrictions on dinner the night before (P=0.013, r2=0.810 for model). The between-laboratory SD of the GI values is approximately 9. Standardized data analysis and low within-subject variation (refCV<30%) are required for accuracy. The results suggest that common misconceptions exist about which factors do and do not need to be controlled to improve precision. Controlled studies and cost-benefit analyses are needed to optimize GI methodology. The trial was registered at clinicaltrials.gov as NCT00260858.

  17. Disease dynamics of Montipora white syndrome within Kaneohe Bay, Oahu, Hawaii: distribution, seasonality, virulence, and transmissibility.

    PubMed

    Aeby, G S; Ross, M; Williams, G J; Lewis, T D; Works, T M

    2010-07-26

    We report on an investigation of Montipora white syndrome (MWS), which is a coral disease reported from Hawaii, U.S.A., that results in tissue loss. Disease surveys of Montipora capitata within Kaneohe Bay (Oahu) found colonies that were affected by MWS on 9 reefs within 3 regions of Kaneohe Bay (south, central, north). Mean MWS prevalence ranged from 0.02 to 0.87% and average number of MWS cases per survey site ranged from 1 to 28 colonies. MWS prevalence and number of cases were significantly lower in the central region as compared to those in the north and south regions of Kaneohe Bay. There was a positive relationship between host abundance and MWS prevalence, and differences in host abundance between sites explained approximately 27% of the variation in MWS prevalence. Reefs in central Kaneohe Bay had lower M. capitata cover and lower MWS levels. MWS prevalence on reefs was neither significantly different between seasons (spring versus fall) nor among 57 tagged colonies that were monitored through time. MWS is a chronic and progressive disease causing M. capitata colonies to lose an average of 3.1% of live tissue mo(-1). Case fatality rate was 28% after 2 yr but recovery occurred in some colonies (32%). Manipulative experiments showed that the disease is acquired through direct contact. This is the first study to examine the dynamics of MWS within Hawaii, and our findings suggest that MWS has the potential to degrade Hawaii's reefs through time.

  18. Approximation concepts for efficient structural synthesis

    NASA Technical Reports Server (NTRS)

    Schmit, L. A., Jr.; Miura, H.

    1976-01-01

    It is shown that efficient structural synthesis capabilities can be created by using approximation concepts to mesh finite element structural analysis methods with nonlinear mathematical programming techniques. The history of the application of mathematical programming techniques to structural design optimization problems is reviewed. Several rather general approximation concepts are described along with the technical foundations of the ACCESS 1 computer program, which implements several approximation concepts. A substantial collection of structural design problems involving truss and idealized wing structures is presented. It is concluded that since the basic ideas employed in creating the ACCESS 1 program are rather general, its successful development supports the contention that the introduction of approximation concepts will lead to the emergence of a new generation of practical and efficient, large scale, structural synthesis capabilities in which finite element analysis methods and mathematical programming algorithms will play a central role.

  19. Verified solutions for the gravitational attraction to an oblate spheroid: Implications for planet mass and satellite orbits

    NASA Astrophysics Data System (ADS)

    Hofmeister, Anne M.; Criss, Robert E.; Criss, Everett M.

    2018-03-01

    Forces external to the oblate spheroid shape, observed from planetary to galactic scales, are demonstrably non-central, which has important ramifications for planetary science. We simplify historic formulae and derive new analytical solutions for the gravitational potential and force outside a constant density oblate. Numerical calculations that sum point mass contributions in a >109 element mesh confirm our equations. We show that contours of constant force and potential about oblate bodies are closely approximated by two confocal families whose foci (f) respectively are (9/10)½ae and (3/5)½ae for a body with f = ae. This leads to useful approximations that address internal density variations. We demonstrate that the force on a general point is not directed towards the oblate's center, nor are forces simply proportional to the inverse square of that distance, despite forces in the equatorial and axial directions pointing towards the center. Our results explain complex dynamics of galactic systems. Because most planets and stars have an aspect ratio >0.9, the spherical approximation is reasonable except for orbits within ∼2 body radii. We show that applying the "generalized" potential, which assumes central forces, yields J2 values half those expected for oblate bodies, and probably underestimates masses of Uranus and Neptune by ∼0.2%. We show that the inner Saturnian moons are subject to non-central forces, which may affect calculations of their orbital precession. Our new series should improve interpretation of flyby data.

  20. Anterior Chamber Air Bubble to Achieve Graft Attachment After DMEK: Is Bigger Always Better?

    PubMed

    Ćirković, Aleksandar; Beck, Christina; Weller, Julia M; Kruse, Friedrich E; Tourtas, Theofilos

    2016-04-01

    To analyze the influence of the size of the air bubble subsequent to Descemet membrane endothelial keratoplasty (DMEK) surgery on the rate of graft detachment and need for rebubbling, the incidence of pupillary block, and the observed endothelial cell loss. This is a single-center, retrospective, consecutive case series of 74 cases undergoing DMEK and fulfilling the inclusion criteria concerning the size of the air bubble at the end of surgery. Based on the medical records, patients were divided into 2 groups (n = 37, respectively). The first group had an air bubble with a volume of approximately 50% and the second group of approximately 80% of the anterior chamber (AC) volume, respectively. Patients who did not comply with instructions to remain in the supine position until complete resorption of AC air or cases in which difficulties in graft preparation (eg, radial breaks) occurred were excluded from data analysis. The central corneal thickness and endothelial cell density were measured 6 months after surgery. Ten of 37 patients (27.0%) in the 50% air bubble group and 3 of 37 patients (8.1%) in the 80% air bubble group needed 1 rebubbling procedure (P = 0.032). There was no difference between the groups after 6 months regarding endothelial cell density and central corneal thickness. No pupillary block was observed. Larger air bubbles of 80% anterior chamber volume decrease the risk of graft detachment after DMEK with no detrimental effect on the outcome and risk for pupillary block.

  1. GECKO: a complete large-scale gene expression analysis platform.

    PubMed

    Theilhaber, Joachim; Ulyanov, Anatoly; Malanthara, Anish; Cole, Jack; Xu, Dapeng; Nahf, Robert; Heuer, Michael; Brockel, Christoph; Bushnell, Steven

    2004-12-10

    Gecko (Gene Expression: Computation and Knowledge Organization) is a complete, high-capacity centralized gene expression analysis system, developed in response to the needs of a distributed user community. Based on a client-server architecture, with a centralized repository of typically many tens of thousands of Affymetrix scans, Gecko includes automatic processing pipelines for uploading data from remote sites, a data base, a computational engine implementing approximately 50 different analysis tools, and a client application. Among available analysis tools are clustering methods, principal component analysis, supervised classification including feature selection and cross-validation, multi-factorial ANOVA, statistical contrast calculations, and various post-processing tools for extracting data at given error rates or significance levels. On account of its open architecture, Gecko also allows for the integration of new algorithms. The Gecko framework is very general: non-Affymetrix and non-gene expression data can be analyzed as well. A unique feature of the Gecko architecture is the concept of the Analysis Tree (actually, a directed acyclic graph), in which all successive results in ongoing analyses are saved. This approach has proven invaluable in allowing a large (approximately 100 users) and distributed community to share results, and to repeatedly return over a span of years to older and potentially very complex analyses of gene expression data. The Gecko system is being made publicly available as free software http://sourceforge.net/projects/geckoe. In totality or in parts, the Gecko framework should prove useful to users and system developers with a broad range of analysis needs.

  2. The inability to pay for health services in Central and Eastern Europe: evidence from six countries

    PubMed Central

    Pavlova, Milena; Rechel, Bernd; Golinowska, Stanisława; Sowada, Christoph; Groot, Wim

    2014-01-01

    Background: Out-of-pocket payments for health services constitute a major financial burden for patients in Central and Eastern European (CEE) countries. Individuals who are unable to pay use different coping strategies (e.g. borrowing money or foregoing service utilization), which can have negative consequences on their health and social welfare. This article explores patients’ inability to pay for outpatient and hospital services in six CEE countries: Bulgaria, Hungary, Lithuania, Poland, Romania and Ukraine. Methods: The analysis is based on quantitative data collected in 2010 in nationally representative surveys. Two indicators of inability to pay were considered: the need to borrow money or sell assets and foregoing service utilization. Statistical analyses were applied to investigate associations between the indicators of inability to pay and individual characteristics. Results: Patient payments are most common in Bulgaria, Ukraine, Romania and Lithuania and often include informal payments. Romanian and, particularly, Ukrainian patients most often face difficulties to pay for health services (with approximately 40% of Ukrainian payers borrowing money or selling assets to cover hospital payments and approximately 60% of respondents who need care foregoing services). Inability to pay mainly affects those with poor health and low incomes. Conclusion: Widespread patient payments constitute a major financial barrier to health service use in CEE. There is a need to formalize them where they are informal and to take measures to protect vulnerable population groups, especially those with limited possibilities to deal with payment difficulties. PMID:24065370

  3. 1. West portal of Tunnel 23, contextual view to northnortheast, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. West portal of Tunnel 23, contextual view to north-northeast, 135mm lens. Camera position is approximately centerline of original Central Pacific Transcontinental line, and bypassed Tunnel '0' (1873) (HAER CA-199) is hidden behind vegetation at center; original line was relocated to present position at right during construction of new line at left in 1909. - Central Pacific Transcontinental Railroad, Tunnel No. 23, Milepost 132.69, Applegate, Placer County, CA

  4. Field Scale Groundwater Nitrate Loading Model for the Central Valley, California, 1945-Current

    NASA Astrophysics Data System (ADS)

    Harter, T.; Dzurella, K.; Bell, A.; Kourakos, G.

    2015-12-01

    Anthropogenic groundwater nitrate contamination in the Central Valley aquifer system, California, is widespread, with over 40% of domestic wells in some counties exceeding drinking water standards. Sources of groundwater nitrate include leaky municipal wastewater systems, municipal wastewater recharge, onsite wastewater treatment (septic) systems, atmospheric nitrogen deposition, animal farming, application of organic waste materials (sludge, biosolids, animal manure) to agricultural lands, and synthetic fertilizer. At the site or field scale, nitrogen inputs to the landscape are balanced by plant nitrogen uptake and harvest, atmospheric nitrogen losses, surface runoff of nitrogen, soil nitrogen storage changes, and leaching to groundwater. Irrigated agriculture is a dominant player in the Central Valley nitrogen cycle: The largest nitrogen fluxes are synthetic fertilizer and animal manure applications to cropland, crop nitrogen uptake, and groundwater nitrogen losses. We construct a historic field/parcel scale groundwater nitrogen loading model distinguishing urban and residential areas, individual animal farming areas, leaky wastewater lagoons, and approximately 50 different categories of agricultural crops. For non-agricultural landuses, groundwater nitrate loading is based on reported leaching values, animal population, and human population. For cropland, groundwater nitrate loading is computed from mass balance, taking into account diverse and historically changing management practices between different crops. Groundwater nitrate loading is estimated for 1945 to current. Significant increases in groundwater nitrate loading are associated with the expansion of synthetic fertilizer use in the 1950s to 1970s. Nitrate loading from synthetic fertilizer use has stagnated over the past 20 years due to improvements in nutrient use efficiency. However, an unbroken 60 year exponential increase in dairy production until the late 2000s has significantly impacted the nitrogen imbalance and is a significant threat to future groundwater quality in the Central Valley system. The model provides the basis for evaluating future planning scenarios to develop and assess long-term solutions for sustainable groundwater quality management.Anthropogenic groundwater nitrate contamination in the Central Valley aquifer system, California, is widespread, with over 40% of domestic wells in some counties exceeding drinking water standards. Sources of groundwater nitrate include leaky municipal wastewater systems, municipal wastewater recharge, onsite wastewater treatment (septic) systems, atmospheric nitrogen deposition, animal farming, application of organic waste materials (sludge, biosolids, animal manure) to agricultural lands, and synthetic fertilizer. At the site or field scale, nitrogen inputs to the landscape are balanced by plant nitrogen uptake and harvest, atmospheric nitrogen losses, surface runoff of nitrogen, soil nitrogen storage changes, and leaching to groundwater. Irrigated agriculture is a dominant player in the Central Valley nitrogen cycle: The largest nitrogen fluxes are synthetic fertilizer and animal manure applications to cropland, crop nitrogen uptake, and groundwater nitrogen losses. We construct a historic field/parcel scale groundwater nitrogen loading model distringuishing urban and residential areas, individual animal farming areas, leaky wastewater lagoons, and approximately 50 different categories of agricultural crops. For non-agricultural landuses, groundwater nitrate loading is based on reported leaching values, animal population, and human population. For cropland, groundwater nitrate loading is computed from mass balance, taking into account diverse and historically changing management practices between different crops. Groundwater nitrate loading is estimated for 1945 to current. Significant increases in groundwater nitrate loading are associated with the expansion of synthetic fertilizer use in the 1950s to 1970s. Nitrate loading from synthetic fertilizer use has stagnated over the past 20 years due to improvements in nutrient use efficiency. However, an unbroken 60 year exponential increase in dairy production until the late 2000s has significantly impacted the nitrogen imbalance and is a significant threat to future groundwater quality in the Central Valley system. The model provides the basis for evaluating future planning scenarios to develop and assess long-term solutions for sustainable groundwater quality management.

  5. Understanding network concepts in modules

    PubMed Central

    2007-01-01

    Background Network concepts are increasingly used in biology and genetics. For example, the clustering coefficient has been used to understand network architecture; the connectivity (also known as degree) has been used to screen for cancer targets; and the topological overlap matrix has been used to define modules and to annotate genes. Dozens of potentially useful network concepts are known from graph theory. Results Here we study network concepts in special types of networks, which we refer to as approximately factorizable networks. In these networks, the pairwise connection strength (adjacency) between 2 network nodes can be factored into node specific contributions, named node 'conformity'. The node conformity turns out to be highly related to the connectivity. To provide a formalism for relating network concepts to each other, we define three types of network concepts: fundamental-, conformity-based-, and approximate conformity-based concepts. Fundamental concepts include the standard definitions of connectivity, density, centralization, heterogeneity, clustering coefficient, and topological overlap. The approximate conformity-based analogs of fundamental network concepts have several theoretical advantages. First, they allow one to derive simple relationships between seemingly disparate networks concepts. For example, we derive simple relationships between the clustering coefficient, the heterogeneity, the density, the centralization, and the topological overlap. The second advantage of approximate conformity-based network concepts is that they allow one to show that fundamental network concepts can be approximated by simple functions of the connectivity in module networks. Conclusion Using protein-protein interaction, gene co-expression, and simulated data, we show that a) many networks comprised of module nodes are approximately factorizable and b) in these types of networks, simple relationships exist between seemingly disparate network concepts. Our results are implemented in freely available R software code, which can be downloaded from the following webpage: http://www.genetics.ucla.edu/labs/horvath/ModuleConformity/ModuleNetworks PMID:17547772

  6. Evidence for Reduced Species Star Formation Rates in the Centers of Massive Galaxies at zeta = 4

    NASA Technical Reports Server (NTRS)

    Jung, Intae; Finkelstein, Steven L.; Song, Mimi; Dickinson, Mark; Dekel, Avishai; Ferguson, Henry C.; Fontana, Adriano; Koekemoer, Anton M.; Lu, Yu; Mobasher, Bahram; hide

    2017-01-01

    We perform the first spatially-resolved stellar population study of galaxies in the early universe z equals 3.5 -6.5, utilizing the Hubble Space Telescope Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) imaging dataset over the GOODS-S field. We select a sample of 418 bright and extended galaxies at z less than or approximately equal to 3.5-6.5 from a parent sample of approximately 8000 photometric-redshift selected galaxies from Finkelstein et al. We first examine galaxies at 3.5 less than or equal to z less than or approximately equal to 4.0 using additional deep K-band survey data from the HAWK-I UDS and GOODS Survey (HUGS) which covers the 4000 Angstrom break at these redshifts. We measure the stellar mass, star formation rate, and dust extinction for galaxy inner and outer regions via spatially-resolved spectral energy distribution fitting based on a Markov Chain Monte Carlo algorithm. By comparing specific star formation rates (sSFRs) between inner and outer parts of the galaxies we find that the majority of galaxies with the high central mass densities show evidence for a preferentially lower sSFR in their centers than in their outer regions, indicative of reduced sSFRs in their central regions. We also study galaxies at z approximately equal to 5 and 6 (here limited to high spatial resolution in the rest-frame ultraviolet only), finding that they show sSFRs which are generally independent of radial distance from the center of the galaxies. This indicates that stars are formed uniformly at all radii in massive galaxies at z approximately equal to 5-6, contrary tomassive galaxies at z. less than approximately equal to 4.

  7. Analysis of anatomic variability in children with low mathematical skills

    NASA Astrophysics Data System (ADS)

    Han, Zhaoying; Fuchs, Lynn; Davis, Nikki; Cannistraci, Christopher J.; Anderson, Adam W.; Gore, John C.; Dawant, Benoit M.

    2008-03-01

    Mathematical difficulty affects approximately 5-9% of the population. Studies on individuals with dyscalculia, a neurologically based math disorder, provide important insight into the neural correlates of mathematical ability. For example, cognitive theories, neuropsychological studies, and functional neuroimaging studies in individuals with dyscalculia suggest that the bilateral parietal lobes and intraparietal sulcus are central to mathematical performance. The purpose of the present study was to investigate morphological differences in a group of third grade children with poor math skills. We compare population averages of children with low math skill (MD) to gender and age matched controls with average math ability. Anatomical data were gathered with high resolution MRI and four different population averaging methods were used to study the effect of the normalization technique on the results. Statistical results based on the deformation fields between the two groups show anatomical differences in the bilateral parietal lobes, right frontal lobe, and left occipital/parietal lobe.

  8. Detection and mapping of mineralized areas in the Cortez-Uinta Belt, Utah-Nevada, using computer-enhanced ERTS imagery

    NASA Technical Reports Server (NTRS)

    Rowan, L. C. (Principal Investigator)

    1976-01-01

    The author has identified the following significant results. Mineralogical differences between hydrothermally altered rocks and most unaltered rocks in south central Nevada cause visible and near infrared (0.45-2.4 micron) spectral reflectance differences which can be used to discriminate broad categories of rocks in multispectral images. The most important mineralogical differences are the increased abundance of goethite, hematite, jarosite, alunite, montmorillonite, and kaolinite in the altered zones. Because of the wavelength positions and widths of the LANDSAT MSS bands, these spectral differences are not apparent in individual or color infrared composite MSS images. The technique developed to enhance these subtle spectral differences combines ratioing of the MSS bands and contrast stretching. Field evaluation of color-ratio composite shows that, after exclusion of alluvial areas, approximately 80% of the green and brown color patterns are related to hydrothermal alteration. The remaining 20% consists mainly of pink hematitic crystallized tuff and tan or red ferruginous shale and siltstone.

  9. Interaction of corneal nociceptive stimulation and lacrimal secretion.

    PubMed

    Situ, Ping; Simpson, Trefford L

    2010-11-01

    To investigate the interaction between corneal stimuli at different positions and tear secretion and to establish relationships between nociceptive stimuli detection thresholds and stimulated tearing. Using a computerized Belmonte-esthesiometer, mechanical and chemical stimuli, from 0% to 200% of the threshold in 50% steps, were delivered (in random order) to the central and peripheral (approximately 2-mm inside the limbus) cornea during four separate sessions to 15 subjects. Immediately after each stimulus, tear meniscus height (TMH) was measured using optical coherence tomography to quantify the amount of lacrimal secretion, and subjects reported whether they felt tears starting to accumulate in their eyes. Thresholds (50% detection) for detection of tearing were estimated. TMH increased with increasing stimulus intensity (P < 0.05), and the overall increase was higher with central stimulation than with peripheral stimulation (P < 0.05). The changes in TMH with threshold-scaled stimulus intensity depended on test location (P < 0.05) and stimulus modality (P < 0.05). The maximum intensity of mechanical stimulation of the central cornea induced the greatest TMH (all P < 0.05). For chemical stimulation, the stimulus intensity required to induce detectable tearing was higher than that required to detect a stimulus and higher in the periphery than at the center (all P < 0.05). Noxious mechanical and chemical stimuli evoked measurable tear secretion, with central corneal mechanical stimulation evoking the strongest lacrimation reflex. Central mechanical corneal stimulation is the most effective stimulus-position pairing and appears to be the major sensory driving force for reflex tear secretion by the lacrimal functional unit.

  10. Different alpha crystallin expression in human age-related and congenital cataract lens epithelium.

    PubMed

    Yang, Jing; Zhou, Sheng; Guo, Minfei; Li, Yuting; Gu, Jianjun

    2016-05-28

    The purpose of this study was to investigate the different expressions of αA-crystallin and αB-crystallin in human lens epithelium of age-related and congenital cataracts. The central part of the human anterior lens capsule approximately 5 mm in diameter together with the adhering epithelial cells, were harvested and processed within 6 hours after cataract surgery from age-related and congenital cataract patients or from normal eyes of fresh cadavers. The mRNA and soluble protein levels of αA-crystallin and αB-crystallin in the human lens epithelium were detected by real-time PCR and western blots, respectively. The mRNA and soluble protein expressions of αA-crystallin and αB-crystallin in the lens epithelium were both reduced in age-related and congenital cataract groups when compared with the normal control group. However, the degree of α-crystallin loss in the lens epithelium was highly correlated with different cataract types. The α-crystallin expression of the lens epithelium was greatly reduced in the congenital cataract group but only moderately decreased in the age-related cataract group. The reduction of αA-crystallin soluble protein levels in the congenital cataract group was approximately 2.4 fold decrease compared with that of the age-related cataract group, while an mRNA fold change of 1.67 decrease was observed for the age-related cataract group. Similarly, the reduction of soluble protein levels of αB-crystallin in the congenital cataract group was approximately a 1.57 fold change compared with that of the age-related cataract group. A 1.75 fold change for mRNA levels compared with that of the age-related cataract group was observed. The results suggest that the differential loss of α-crystallin in the human lens epithelium could be associated with the different mechanisms of cataractogenesis in age-related versus congenital cataracts, subsequently resulting in different clinical presentations.

  11. Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein.

    PubMed Central

    Hsiao, K K; Groth, D; Scott, M; Yang, S L; Serban, H; Rapp, D; Foster, D; Torchia, M; Dearmond, S J; Prusiner, S B

    1994-01-01

    Two lines of transgenic (Tg) mice expressing high (H) levels of the mutant P101L prion protein (PrP) developed a neurologic illness and central nervous system pathology indistinguishable from experimental murine scrapie; these mice were designated Tg(MoPrP-P101L)H. Brain homogenates from Tg(MoPrP-P101L)H mice were inoculated intracerebrally into CD-1 Swiss mice, Syrian hamsters, and Tg196 mice, Tg mice expressing the MoPrP-P101L transgene at low levels. None of the CD-1 mice developed central nervous system dysfunction, whereas approximately 10% of hamsters and approximately 40% of the Tg196 mice manifested neurologic signs between 117 and 639 days after inoculation. Serial transmission of neurodegeneration in Tg196 mice and Syrian hamsters was initiated with brain extracts, producing incubation times of approximately 400 and approximately 75 days, respectively. Although the Tg(MoPrP-P101L)H mice appear to accumulate only low levels of infections prions in their brains, the serial transmission of disease to inoculated recipients argues that prion formation occurs de novo in the brains of these uninoculated animals. These Tg mouse studies, taken together with similar findings in humans dying of inherited prion diseases, provide additional evidence that prions lack a foreign nucleic acid. Images PMID:7916462

  12. Development of a transition pathway model using three traditional variables to describe the main structural characteristics of a forest stand type, size, and density

    Treesearch

    Chad Larson

    2006-01-01

    The Central Hardwood Region is a unique forest region in the United States, encompassing 340 million acres of land, of which 100 million acres are forested (Parker 1993). The region contains one-fourth of the U.S. population, with approximately 90 percent of the land in private ownership (Parker 1993). In general, private forested lands in the Central Hardwood Region...

  13. Tertiary montane origin of the Central Asian flora, evidence inferred from cpDNA sequences of Atraphaxis (Polygonaceae)

    Treesearch

    Ming-Li Zhang; Stewart C. Sanderson; Yan-Xia Sun; Byalt V. Vyacheslav; Xiao-Li Hao

    2014-01-01

    Atraphaxis has approximately 25 species and a distribution center in Central Asia. It has been previously used to hypothesize an origin from montane forest. We sampled 18 species covering three sections within the genus and sequenced five cpDNA spacers, atpB-rbcL, psbK-psbI, psbAtrnH, rbcL, and trnL-trnF. BEAST was used to reconstruct phylogenetic relationship and time...

  14. Newly identified "Tunnunik" impact structure, Prince Albert Peninsula, northwestern Victoria Island, Arctic Canada

    NASA Astrophysics Data System (ADS)

    Dewing, Keith; Pratt, Brian R.; Hadlari, Thomas; Brent, Tom; BÉDard, Jean; Rainbird, Robert H.

    2013-02-01

    Regional geological mapping of the glaciated surface of northwestern Victoria Island in the western Canadian Arctic revealed an anomalous structure in otherwise flat-lying Neoproterozoic and lower Paleozoic carbonate rocks, located south of Richard Collinson Inlet. The feature is roughly circular in plan view, approximately 25 km in diameter, and characterized by quaquaversal dips of approximately 45°, decreasing laterally. The core of the feature also exhibits local vertical dips, low-angle reverse faults, and drag folds. Although brecciation was not observed, shatter cones are pervasive in all lithologies in the central area, including 723 Ma old dikes that penetrate Neoproterozoic limestones. Their abundance decreases distally, and none was observed in surrounding, horizontally bedded strata. This circular structure is interpreted as a deeply eroded meteorite impact crater of the complex type, and the dipping strata as the remnants of the central uplift. The variation in orientation and shape of shatter cones point to variably oriented stresses with the passage of the shock wave, possibly related to the presence of pore water in the target strata as well as rock type and lithological heterogeneities, especially bed thickness. Timing of impact is poorly constrained. The youngest rocks affected are Late Ordovician (approximately 450 Ma) and the impact structure is mantled by undisturbed postglacial sediments. Regional, hydrothermal dolomitization of the Ordovician limestones, possibly in the Late Devonian (approximately 360 Ma), took place before the impact, and widespread WSW-ENE-trending normal faults of probable Early Cretaceous age (approximately 130 Ma) apparently cross-cut the impact structure.

  15. The distribution and most recent common ancestor of the 17q21 inversion in humans.

    PubMed

    Donnelly, Michael P; Paschou, Peristera; Grigorenko, Elena; Gurwitz, David; Mehdi, Syed Qasim; Kajuna, Sylvester L B; Barta, Csaba; Kungulilo, Selemani; Karoma, N J; Lu, Ru-Band; Zhukova, Olga V; Kim, Jong-Jin; Comas, David; Siniscalco, Marcello; New, Maria; Li, Peining; Li, Hui; Manolopoulos, Vangelis G; Speed, William C; Rajeevan, Haseena; Pakstis, Andrew J; Kidd, Judith R; Kidd, Kenneth K

    2010-02-12

    The polymorphic inversion on 17q21, sometimes called the microtubular associated protein tau (MAPT) inversion, is an approximately 900 kb inversion found primarily in Europeans and Southwest Asians. We have identified 21 SNPs that act as markers of the inverted, i.e., H2, haplotype. The inversion is found at the highest frequencies in Southwest Asia and Southern Europe (frequencies of approximately 30%); elsewhere in Europe, frequencies vary from < 5%, in Finns, to 28%, in Orcadians. The H2 inversion haplotype also occurs at low frequencies in Africa, Central Asia, East Asia, and the Americas, though the East Asian and Amerindian alleles may be due to recent gene flow from Europe. Molecular evolution analyses indicate that the H2 haplotype originally arose in Africa or Southwest Asia. Though the H2 inversion has many fixed differences across the approximately 900 kb, short tandem repeat polymorphism data indicate a very recent date for the most recent common ancestor, with dates ranging from 13,600 to 108,400 years, depending on assumptions and estimation methods. This estimate range is much more recent than the 3 million year age estimated by Stefansson et al. in 2005. Copyright (c) 2010 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  16. Partial differential equation techniques for analysing animal movement: A comparison of different methods.

    PubMed

    Wang, Yi-Shan; Potts, Jonathan R

    2017-03-07

    Recent advances in animal tracking have allowed us to uncover the drivers of movement in unprecedented detail. This has enabled modellers to construct ever more realistic models of animal movement, which aid in uncovering detailed patterns of space use in animal populations. Partial differential equations (PDEs) provide a popular tool for mathematically analysing such models. However, their construction often relies on simplifying assumptions which may greatly affect the model outcomes. Here, we analyse the effect of various PDE approximations on the analysis of some simple movement models, including a biased random walk, central-place foraging processes and movement in heterogeneous landscapes. Perhaps the most commonly-used PDE method dates back to a seminal paper of Patlak from 1953. However, our results show that this can be a very poor approximation in even quite simple models. On the other hand, more recent methods, based on transport equation formalisms, can provide more accurate results, as long as the kernel describing the animal's movement is sufficiently smooth. When the movement kernel is not smooth, we show that both the older and newer methods can lead to quantitatively misleading results. Our detailed analysis will aid future researchers in the appropriate choice of PDE approximation for analysing models of animal movement. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Bayesian alternative to the ISO-GUM's use of the Welch Satterthwaite formula

    NASA Astrophysics Data System (ADS)

    Kacker, Raghu N.

    2006-02-01

    In certain disciplines, uncertainty is traditionally expressed as an interval about an estimate for the value of the measurand. Development of such uncertainty intervals with a stated coverage probability based on the International Organization for Standardization (ISO) Guide to the Expression of Uncertainty in Measurement (GUM) requires a description of the probability distribution for the value of the measurand. The ISO-GUM propagates the estimates and their associated standard uncertainties for various input quantities through a linear approximation of the measurement equation to determine an estimate and its associated standard uncertainty for the value of the measurand. This procedure does not yield a probability distribution for the value of the measurand. The ISO-GUM suggests that under certain conditions motivated by the central limit theorem the distribution for the value of the measurand may be approximated by a scaled-and-shifted t-distribution with effective degrees of freedom obtained from the Welch-Satterthwaite (W-S) formula. The approximate t-distribution may then be used to develop an uncertainty interval with a stated coverage probability for the value of the measurand. We propose an approximate normal distribution based on a Bayesian uncertainty as an alternative to the t-distribution based on the W-S formula. A benefit of the approximate normal distribution based on a Bayesian uncertainty is that it greatly simplifies the expression of uncertainty by eliminating altogether the need for calculating effective degrees of freedom from the W-S formula. In the special case where the measurand is the difference between two means, each evaluated from statistical analyses of independent normally distributed measurements with unknown and possibly unequal variances, the probability distribution for the value of the measurand is known to be a Behrens-Fisher distribution. We compare the performance of the approximate normal distribution based on a Bayesian uncertainty and the approximate t-distribution based on the W-S formula with respect to the Behrens-Fisher distribution. The approximate normal distribution is simpler and better in this case. A thorough investigation of the relative performance of the two approximate distributions would require comparison for a range of measurement equations by numerical methods.

  18. Properties of gamma-ray burst progenitor stars.

    PubMed

    Kumar, Pawan; Narayan, Ramesh; Johnson, Jarrett L

    2008-07-18

    We determined some basic properties of stars that produce spectacular gamma-ray bursts at the end of their lives. We assumed that accretion of the outer portion of the stellar core by a central black hole fuels the prompt emission and that fall-back and accretion of the stellar envelope later produce the plateau in the x-ray light curve seen in some bursts. Using x-ray data for three bursts, we estimated the radius of the stellar core to be approximately (1 - 3) x 10(10) cm and that of the stellar envelope to be approximately (1 - 2) x 10(11) cm. The density profile in the envelope is fairly shallow, with rho approximately r(-2) (where rho is density and r is distance from the center of the explosion). The rotation speeds of the core and envelope are approximately 0.05 and approximately 0.2 of the local Keplerian speed, respectively.

  19. Right Site, Wrong Route - Cannulating the Left Internal Jugular Vein.

    PubMed

    Paik, Peter; Arukala, Sanjay K; Sule, Anupam A

    2018-01-09

    Central venous catheters are placed in approximately five million patients annually in the US. The preferred site of insertion is one with fewer risks and easier access. Although the right internal jugular vein is preferred, on occasion, the left internal jugular may have to be accessed. A patient was admitted for septic shock, cerebrovascular accident, and non-ST-segment elevation myocardial infarction. A central venous line was needed for antibiotic and vasopressor administration. Due to trauma from a fall to the right side and previously failed catheterization attempts at the left subclavian and femoral veins, the left internal jugular vein was accessed. On chest radiography for confirmation, the left internal jugular central venous catheter was seen projecting down the left paraspinal region. It did not take the expected course across the midline toward the right and into the superior vena cava (SVC). A review of a computed tomography (CT) scan of the chest with contrast done on a prior admission revealed a duplicated SVC on the left side that had not been reported in the original CT scan interpretation. A left-sided SVC is present in approximately 0.3% to 0.5% of the population, with 90% of these draining into the coronary sinus. During placements of central venous lines and pacemakers, irritation of the coronary sinus may result in hypotension, arrhythmia, myocardial ischemia, or cardiac arrest. A widened mediastinum can be an indication of a duplicated SVC. When attempting a left internal jugular vein central venous catheter placement, it is important to be aware of venous anomalies in order to prevent complications.

  20. Idealized model of polar cap currents, fields, and auroras

    NASA Technical Reports Server (NTRS)

    Cornwall, J. M.

    1985-01-01

    During periods of northward Bz, the electric field applied to the magnetosphere is generally opposite to that occurring during southward Bz and complicated patterns of convection result, showing some features reversed in comparison with the southward Bz case. A study is conducted of a simple generalization of early work on idealized convection models, which allows for coexistence of sunward convection over the central polar cap and antisunward convection elsewhere in the cap. The present model, valid for By approximately 0, has a four-cell convection pattern and is based on the combination of ionospheric current conservation with a relation between parallel auroral currents and parallel potential drops. Global magnetospheric issues involving, e.g., reconnection are not considered. The central result of this paper is an expression giving the parallel potential drop for polar cap auroras (with By approximately 0) in terms of the polar cap convection field profile.

  1. Population genetic structure of codling moth (Lepidoptera: Tortricidae) from apple orchards in central Chile.

    PubMed

    Fuentes-Contreras, Eduardo; Espinoza, Juan L; Lavandero, Blas; Ramírez, Claudio C

    2008-02-01

    Codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), is the main pest of pome fruits worldwide. Despite its economic importance, little is known about the genetic structure and patterns of dispersal at the local and regional scale, which are important aspects for establishing a control strategy for this pest. An analysis of genetic variability using microsatellites was performed for 11 codling moth populations in the two major apple (Malus domestica Borkh) cropping regions in central Chile. Despite the geographical distances between some populations (approximately 185 km), there was low genetic differentiation among populations (F(ST) = 0.002176), with only slight isolation by distance. Only approximately 0.2% of the genetic variability was found among the populations. Geographically structured genetic variation was independent of apple orchard management (production or abandoned). These results suggest a high genetic exchange of codling moth between orchards, possibly mediated by human activities related to fruit production.

  2. Surname complex network for Brazil and Portugal

    NASA Astrophysics Data System (ADS)

    Ferreira, G. D.; Viswanathan, G. M.; da Silva, L. R.; Herrmann, H. J.

    2018-06-01

    We present a study of social networks based on the analysis of Brazilian and Portuguese family names (surnames). We construct networks whose nodes are names of families and whose edges represent parental relations between two families. From these networks we extract the connectivity distribution, clustering coefficient, shortest path and centrality. We find that the connectivity distribution follows an approximate power law. We associate the number of hubs, centrality and entropy to the degree of miscegenation in the societies in both countries. Our results show that Portuguese society has a higher miscegenation degree than Brazilian society. All networks analyzed lead to approximate inverse square power laws in the degree distribution. We conclude that the thermodynamic limit is reached for small networks (3 or 4 thousand nodes). The assortative mixing of all networks is negative, showing that the more connected vertices are connected to vertices with lower connectivity. Finally, the network of surnames presents some small world characteristics.

  3. Do pathogens become more virulent as they spread? Evidence from the amphibian declines in Central America

    PubMed Central

    Phillips, Ben L.; Puschendorf, Robert

    2013-01-01

    The virulence of a pathogen can vary strongly through time. While cyclical variation in virulence is regularly observed, directional shifts in virulence are less commonly observed and are typically associated with decreasing virulence of biological control agents through coevolution. It is increasingly appreciated, however, that spatial effects can lead to evolutionary trajectories that differ from standard expectations. One such possibility is that, as a pathogen spreads through a naive host population, its virulence increases on the invasion front. In Central America, there is compelling evidence for the recent spread of pathogenic Batrachochytrium dendrobatidis (Bd) and for its strong impact on amphibian populations. Here, we re-examine data on Bd prevalence and amphibian population decline across 13 sites from southern Mexico through Central America, and show that, in the initial phases of the Bd invasion, amphibian population decline lagged approximately 9 years behind the arrival of the pathogen, but that this lag diminished markedly over time. In total, our analysis suggests an increase in Bd virulence as it spread southwards, a pattern consistent with rapid evolution of increased virulence on Bd's invading front. The impact of Bd on amphibians might therefore be driven by rapid evolution in addition to more proximate environmental drivers. PMID:23843393

  4. Do pathogens become more virulent as they spread? Evidence from the amphibian declines in Central America.

    PubMed

    Phillips, Ben L; Puschendorf, Robert

    2013-09-07

    The virulence of a pathogen can vary strongly through time. While cyclical variation in virulence is regularly observed, directional shifts in virulence are less commonly observed and are typically associated with decreasing virulence of biological control agents through coevolution. It is increasingly appreciated, however, that spatial effects can lead to evolutionary trajectories that differ from standard expectations. One such possibility is that, as a pathogen spreads through a naive host population, its virulence increases on the invasion front. In Central America, there is compelling evidence for the recent spread of pathogenic Batrachochytrium dendrobatidis (Bd) and for its strong impact on amphibian populations. Here, we re-examine data on Bd prevalence and amphibian population decline across 13 sites from southern Mexico through Central America, and show that, in the initial phases of the Bd invasion, amphibian population decline lagged approximately 9 years behind the arrival of the pathogen, but that this lag diminished markedly over time. In total, our analysis suggests an increase in Bd virulence as it spread southwards, a pattern consistent with rapid evolution of increased virulence on Bd's invading front. The impact of Bd on amphibians might therefore be driven by rapid evolution in addition to more proximate environmental drivers.

  5. Space Radar Image of Central Java, Indonesia

    NASA Image and Video Library

    1999-04-15

    The summits of two large volcanoes in Central Java, Indonesia are shown in the center of this radar image. Lava flows of different ages and surface roughness appear in shades of green and yellow surrounding the summit of Mt. Merbabu (mid-center) and Mt. Merapi (lower center). Mt. Merapi erupted on November 28, 1994 about six weeks after this image was taken. The eruption killed more than 60 people and forced the evacuation of more than 6,000 others. Thousands of other residents were put on alert due to the possibility of volcanic debris mudflows, called lahars, that threatened nearby towns. Mt. Merapi is located approximately 40 kilometers (25 miles) north of Yogyakarta, the capital of Central Java. The older volcano at the top of the image is unnamed. Lake Rawapening is the dark blue feature in the upper right. The light blue area southeast of the lake is the city of Salatiga. Directly south of Salatiga and southeast of Mt. Merapi is the city of Boyolali. Scientists are studying Mt. Merapi as part of the international "Decade Volcanoes" project, because of its recent activity and potential threat to local populations. The radar data are being used to identify and distinguish a variety of volcanic features. http://photojournal.jpl.nasa.gov/catalog/PIA01782

  6. Application of fecal near-infrared spectroscopy and nutritional balance software to monitor diet quality and body condition in beef cows grazing Arizona rangeland.

    PubMed

    Tolleson, D R; Schafer, D W

    2014-01-01

    Monitoring the nutritional status of range cows is difficult. Near-infrared spectroscopy (NIRS) of feces has been used to predict diet quality in cattle. When fecal NIRS is coupled with decision support software such as the Nutritional Balance Analyzer (NUTBAL PRO), nutritional status and animal performance can be monitored. Approximately 120 Hereford and 90 CGC composite (50% Red Angus, 25% Tarentaise, and 25% Charolais) cows grazing in a single herd were used in a study to determine the ability of fecal NIRS and NutbalPro to project BCS (1 = thin and 9 = fat) under commercial scale rangeland conditions in central Arizona. Cattle were rotated across the 31,000 ha allotment at 10 to 20 d intervals. Cattle BCS and fecal samples (approximately 500 g) composited from 5 to 10 cows were collected in the pasture approximately monthly at the midpoint of each grazing period. Samples were frozen and later analyzed by NIRS for prediction of diet crude protein (CP) and digestible organic matter (DOM). Along with fecal NIRS predicted diet quality, animal breed type, reproductive status, and environmental conditions were input to the software for each fecal sampling and BCS date. Three different evaluations were performed. First, fecal NIRS and NutbalPro derived BCS was projected forward from each sampling as if it were a "one-time only" measurement. Second, BCS was derived from the average predicted weight change between 2 sampling dates for a given period. Third, inputs to the model were adjusted to better represent local animals and conditions. Fecal NIRS predicted diet quality varied from a minimum of approximately 5% CP and 57% DOM in winter to a maximum of approximately 11% CP and 60% DOM in summer. Diet quality correlated with observed seasonal changes and precipitation events. In evaluation 1, differences in observed versus projected BCS were not different (P > 0.1) between breed types but these values ranged from 0.1 to 1.1 BCS in Herefords and 0.0 to 0.9 in CGC. In evaluation 2, differences in observed versus projected BCS were not different (P > 0.1) between breed types but these values ranged from 0.00 to 0.46 in Hereford and 0.00 to 0.67 in CGC. In evaluation 3, the range of differences between observed and projected BCS was 0.04 to 0.28. The greatest difference in projected versus observed BCS occurred during periods of lowest diet quality. Body condition was predicted accurately enough to be useful in monitoring the nutrition of range beef cows under the conditions of this study.

  7. Different impacts of mega-ENSO and conventional ENSO on the Indian summer rainfall: developing phase

    NASA Astrophysics Data System (ADS)

    Zhang, Lei; Wu, Zhiwei; Zhou, Yefan

    2016-04-01

    Mega-El Niño-Southern Oscillation (ENSO), a boarder version of conventional ENSO, is found to be a main driving force of Northern Hemisphere summer monsoon rainfall including the Indian summer rainfall (ISR). The simultaneous impacts of "pure" mega-ENSO and "pure" conventional ENSO events on the ISR in its developing summer remains unclear. This study examines the different linkages between mega-ENSO-ISR and conventional ENSO-ISR. During the developing summer of mega-El Niño, negative rainfall anomalies are seen over the northeastern Indian subcontinent, while the anomalous rainfall pattern is almost the opposite for mega-La Niña; as for the conventional ENSO, the approximate "linear opposite" phenomenon vanishes. Furthermore, the global zonal wave trains anomalous are found at mid-latitude zones, with a local triple circulation pattern over the central-east Eurasia during mega-ENSO events, which might be an explanation of corresponding rainfall response over the Indian Peninsula. Among 106-year historical run (1900-2005) of 9 state-of-the-art models from the Coupled Model Inter-comparison Project Phase 5 (CMIP5), HadGEM2-ES performs a promising skill in simulating the anomalous circulation pattern over mid-latitude and central-east Eurasia while CanESM2 cannot. Probably, it is the models' ability of capturing the mega-ENSO-ISR linkage and the characteristic of mega-ENSO that make the difference.

  8. Multiple Invasions into Freshwater by Pufferfishes (Teleostei: Tetraodontidae): A Mitogenomic Perspective

    PubMed Central

    Yamanoue, Yusuke; Miya, Masaki; Doi, Hiroyuki; Mabuchi, Kohji; Sakai, Harumi; Nishida, Mutsumi

    2011-01-01

    Pufferfishes of the Family Tetraodontidae are the most speciose group in the Order Tetraodontiformes and mainly inhabit coastal waters along continents. Although no members of other tetraodontiform families have fully discarded their marine lives, approximately 30 tetraodontid species spend their entire lives in freshwaters in disjunct tropical regions of South America, Central Africa, and Southeast Asia. To investigate the interrelationships of tetraodontid pufferfishes and thereby elucidate the evolutionary origins of their freshwater habitats, we performed phylogenetic analysis based on whole mitochondrial genome sequences from 50 tetraodontid species and closely related species (including 31 newly determined sequences). The resulting phylogenies reveal that the family is composed of four major lineages and that freshwater species from the different continents are independently nested in two of the four lineages. A monophyletic origin of the use of freshwater habitats was statistically rejected, and ancestral habitat reconstruction on the resulting tree demonstrates that tetraodontids independently entered freshwater habitats in different continents at least three times. Relaxed molecular-clock Bayesian divergence time estimation suggests that the timing of these invasions differs between continents, occurring at 0–10 million years ago (MA) in South America, 17–38 MA in Central Africa, and 48–78 MA in Southeast Asia. These timings are congruent with geological events that could facilitate adaptation to freshwater habitats in each continent. PMID:21364898

  9. Understanding the Star Formation Process in the Filamentary Dark Cloud GF 9: Near-Infrared Observations

    NASA Technical Reports Server (NTRS)

    Ciardi, David R.; Woodward, Charles E.; Clemens, Dan P.; Harker, David E.; Rudy, Richard J.

    1998-01-01

    We have performed a near-infrared JHK survey of a dense core and a diffuse filament region within the filamentary dark cloud GF 9 (LDN 1082). The core region is associated with the IRAS point source PSC 20503+6006 and is suspected of being a site of star formation. The diffuse filament region has no associated IRAS point sources and is likely quiescent. We find that neither the core nor the filament region appears to contain a Class I or Class II young stellar object. As traced by the dust extinction, the core and filament regions contain 26 and 22 solar mass, respectively, with an average H2 volume density for both regions of approximately 2500/cu cm. The core region contains a centrally condensed extinction maximum with a peak extinction of A(sub v) greater than or approximately equal to 10 mag that appears to be associated with the IRAS point source. The average H2 volume density of the extinction core is approximately 8000/cu cm. The dust within the filament, however, shows no sign of a central condensation and is consistent with a uniform-density cylindrical distribution.

  10. Gynecologic disorders diagnosed during deployment to Southwest/Central Asia, active component females, U.S. Armed Forces, 2008-2013.

    PubMed

    2014-08-01

    Service women in the U.S. Armed Forces face unique challenges that may lead to or exacerbate gynecologic disorders - particularly during deployment. This report documented that approximately one in 10 military women who served in Southwest/Central Asia were diagnosed with a gynecologic disorder at least once during deployment. In addition, gynecologic disorders accounted for approximately one of every 20 medical evacuations of female service members from the war zone. A majority of clinically significant gynecologic disorder cases were attributable to irregular menstruation/bleeding or unspecified inflammation or pain of the female genital organs. Incidence rates of gynecologic disorder diagnoses were higher among black, non-Hispanic service women, among younger women, and among those in the Army and in motor transport and communications/intelligence occupations. Approximately 50% of gynecologic disorder cases had received gynecologic care within 6 months prior to deployment and nearly 90% had received care within 2 years of deployment. Despite pre-deployment care, it is apparent from this report that service women need continuous access to gynecologic care during deployment, particularly if conditions during deployment lead to and exacerbate gynecologic disorders.

  11. Sculpting a Pre-Planetary Nebula with a Precessing Jet: IRAS 16342-3814

    NASA Technical Reports Server (NTRS)

    Sahai, R.; Le Mignant, D.; Sanchez Contreras, C.; Campbell, R. D.; Chaffee, F. H.

    2005-01-01

    We have imaged the bipolar pre-planetary nebula IRAS 16342-3814 with the Keck adaptive optics (AO) system in four near-infrared bands in the 1.6-4.7 (micro)m range. The lobes, which showed smoothly varying brightness distributions in previous optical images taken with the Hubble Space Telescope, have a limb-brightened appearance in the AO images, with a remarkable corkscrew structure inscribed on the lobe walls. A well-collimated, precessing jet with a diameter less than or approximately equal to 100 AU and a precession period less than or approximately equal to 50 yr, interacting with ambient circumstellar material, is most likely responsible for the corkscrew structure and the lobes, as indicated by a detailed comparison of our observations with published numerical simulations. The very red colors of the lobes in the near-infrared, coupled with their visibility at optical wavelengths, require that at least half, but not all, of the light of the central star be trapped by a compact circumstellar dust cloud heated to approximately 600-700 K and reradiated in the infrared. The lobes are thus illuminated both by the infrared light from this dust cloud as well as by the optical light from the central star.

  12. Propagation of cosmic rays through the atmosphere in the quark-gluon strings model

    NASA Technical Reports Server (NTRS)

    Erlykin, A. D.; Krutikova, N. P.; Shabelski, Y. M.

    1985-01-01

    The quark-gluon strings model succeeds in the description of multiple hadron production in the central rapidity region of nucleon-nucleon interctions. This model was developed for hadron-nucleus interactions and used for calculation of the cosmic ray propagation through the atmosphere. It is shown that at energies 10 to the 11th power to the 12th power eV, this model gives a satisfactory description of experimental data. But with the increase of the energy up to approximately 10 to the 14th power eV, results of calculations and of experiments begin to differ and this difference rises with the energy. It may indicate that the scaling violation in the fragmentation region of inclusive spectra for hadron-nucleus interactions is stronger than in the quark-gluon strings model.

  13. Effect of Varying Crustal Thickness on CHAMP Geopotential Data

    NASA Technical Reports Server (NTRS)

    Taylor, P. T.; Kis, K. I.; vonFrese, R. R. B.; Korhonen, J. V.; Wittmann, G.; Kim, H. R.; Potts, L. V.

    2003-01-01

    To determine the effect of crustal thickness variation on satellite-altitude geopotential anomalies we compared two regions of Europe with vastly different values, Central/Southern Finland and the Pannonian Basin. Crustal thickness exceeds 62 km in Finland and is less than 26 km in the Pannonian Basin. Heat-flow maps indicate that the thinner and more active crust of the Pannonian Basin has a value nearly three times that of the Finnish Svecofennian Province. Ground based gravity mapping in Hungary shows that the free-air gravity anomalies across the Pannonian Basin are near 0 to +20 mGal with shorter wavelength anomalies from +40 to less than +60 mGal and some 0 to greater than -20 mGal. Larger anomalies are detected in the mountainous areas. The minor value anomalies can indicate the isostatic equilibrium for Hungary (the central part of the Pannonian Basin). Gravity data over Finland are complicated by de-glaciation. CHAMP gravity data (400 km) indicates a west-east positive gradient of greater than 4 mGal across Central/Southern Finland and an ovoid positive anomaly (approximately 4 mGal) quasi-coincidental with the magnetic anomaly traversing the Pannonian Basin. CHAMP magnetic data (425 km) reveal elongated semicircular negative anomalies for both regions with South-Central Finland having larger amplitude (less than -6 nT) than that over the Pannonian Basin, Hungary (less than -5 nT). In both regions subducted oceanic lithosphere has been proposed as the anomalous body.

  14. History of ground-water pumpage and water-level decline in the Black Creek and upper Cape Fear aquifers of the central coastal plain of North Carolina

    USGS Publications Warehouse

    Winner, M.D.; Lyke, W.L.

    1986-01-01

    Historical ground-water withdrawals and a general water-level decline in the Black Creek and upper Cape Fear aquifers of the central Coastal Plain of North Carolina are documented. Total municipal and industrial pumpage from these aquifers has increased from approximately 120,000 gal/day (gpd) in 1910 to >21 million gpd in 1980. Major pumpage, > 10,000 gpd, began around 1900. Since that time, per capita water use in the central Coastal Plain area has ranged from 17 to 172 gpd/person. The higher values partially represent the increasing availability and use of modern conveniences since the World War II era. The range of per capita water use can be subdivided according to general water-use and population characteristics for both urban and rural areas. The pumpage of ground water from the Black Creek and upper Cape Fear aquifers has created water-level declines from 0.5 to 4.9 ft/year since 1900. Approximately a third of the study area has experienced a decline > 50 ft up to the period 1979-1981, with 148 ft being the maximum.

  15. Central florida phosphate industry. Volume II. background and alternatives assessment. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1978-11-01

    The Central Florida Phosphate District encompasses an area of approximately 2000 square miles in Polk, Hillsborough, Manatee, Hardee, and DeSoto Counties, Florida. There are currently 17 potential new source mines in the district. This EIS assessed areawide and cumulative effects on the entire area and provides the basis for development of site specific EISs. The final EIS establishes a scenario of phosphate development which was determined to be as compatible as practicable with other desired and intended land uses in Central Florida. Volume II describes the Central Florida Phosphate Industry and the Natural and man-made environments of the study area.more » Several scenarios are presented as decision alternatives and primary and secondary effects are assessed and compared.« less

  16. Is HL Tauri and FU Orionis system in quiescence?

    NASA Technical Reports Server (NTRS)

    Lin, D. N. C.; Hayashi, M.; Bell, K. R.; Ohashi, N.

    1994-01-01

    A recent Nobeyama map of HL Tau reveals that gas is infalling in a flattened region approximately 1400 AU around the central star. The apparent motion of the gas provides the necessary condition for the formation of a Keplerian disk with a radius comparable to the size of the primordial solar nebula. The inferred mass infall rate onto the disk is approximately equal to 5 x 10(exp -6) solar mass/yr, which greatly exceeds the maximum estimate of the accretion rate onto the central star (approximately 7 x 10(exp -7) solar mass/yr). Consequently, mass must currently be accumulating in the disk. The estimated age and disk mass of HL Tau suggest that the accumulated matter has been flushed repeatedly on a timescale less than 10(exp 4) yr. Based on the similarites between their evolution patterns, we propose that HL Tau is an FU Orionis system in quiescence. In addition to HL Tau, 14 out of 86 pre-main-sequence stars in the Taurus-Auriga dark clouds have infrared luminosities much greater than their otherwise normal extinction-corrected stellar luminosities. These sources also tend to have flat spectra which may be due to the reprocessing of radiation by dusty, flattened, collapsing envelopes with infall rates a few 10(exp -6) solar mass/yr. Such rates are much larger than estimated central accretion rates for these systems, which suggests that mass must also be accumulating in these disks. If these sources are FU Orionis stars in quiescence, similar to HL Tau, their age and relative abundance imply that the FU Orionis phase occurs over a timescale of approixmately 10(exp 5) yr, and the quiescent phase between each outburst lasts approximately 10(exp 3) =10(exp 4) yr. These inferred properties are compatible with the scenario that FU Orionis outbursts are regulated by a thermal instability in the inner region of the disk.

  17. The nature of the dense obscuring material in the nucleus of NGC 1068

    NASA Technical Reports Server (NTRS)

    Tacconi, L. J.; Genzel, R.; Blietz, M.; Cameron, M.; Harris, A. I.; Madden, S.

    1994-01-01

    High spatial and spectral resolution observations of the distribution, physical parameters, and kinematics of the molecular interstellar medium toward the nucleus of the Seyfert 2 galaxy NGC 1068 are reported. The data consist of 2.4 by 3.4 arcseconds resolution interferometry of the 88.6 GHz HCN J = 1 towards 0 line at 17 km/s spectral resolution, single dish observations of several mm/submm isotopic lines of CO and HCN, and 0.85 arcseconds imaging spectroscopy of the 2.12 micron H2 S(1) line at a velocity resolution of 110 km/s. The central few hundred parsecs of NGC 1068 contain a system of dense (N(H2) approximately 10(exp 5) cm(exp -3)), warm (T greater than or equal to 70 K) molecular cloud cores. The low density molecular envelopes have probably been stripped by the nuclear wind and radiation. The molecular gas layer is located in the plane of NGC 1068's large scale disk (inclination approximately 35 deg) and orbits in elliptical streamlines in response to the central stellar bar. The spatial distribution of the 2 micron H2 emission suggests that gas is shocked at the leading edge of the bar, probably resulting in gas influx into the central 100 pc at a rate of a few solar mass per year. In addition to large scale streaming (with a solid body rotation curve), the HCN velocity field requires the presence of random motions of order 100 km/s. We interpret these large random motions as implying the nuclear gas disk to be very thick (scale height/radius approximately 1), probably as the result of the impact of nuclear radiation and wind on orbiting molecular clouds. Geometry and column density of the molecular cloud layer between approximately 30 pc to 300 pc from the nucleus can plausibly account for the nuclear obscuration and anisotropy of the radiation field in the visible and UV.

  18. Hydraulic seals and their origin: Evidence from the stable isotope geochemistry of dolomites in the Middle Ordovician St. Peter Sandstone, Michigan basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Winter, B.L.; Johnson, C.M.; Valley, J.W.

    1995-01-01

    Regionally extensive, overpressured natural gas pools within the St. Peter Sandstone (Middle Ordovician) of the Michigan basin are bounded by rock types that include 3-7-m-thick zones of low-permeability, low-porosity carbonates or diagenetically banded quartz sandstones. Replacive dolomite from an approximately 5-m-thick carbonate interval in the east-central portion of the Michigan basin has very low {delta}{sup 13}C values that systematically decrease from approximately -5% at the top to -10% (PDB) at the base. {delta}{sup 18}O values for the replacive dolomite also decrease systematically with depth from approximately 27 to 23% (SMOW). These data suggest an upward decrease in isotope exchange betweenmore » the replacive dolomitization fluid and the precursors rock (i.e., the system was rock dominated at the top of the carbonate interval), which implies upward, cross-formational movement of the dolomitizing fluid. Fluid-rock interaction modeling suggest that the dolomitizing fluid had a total dissolved carbon (TDC) content of approximately 4000 ppm and a {delta}{sup 13}C value of -27%, which indicates that the carbon was primarily derived from organic diagenesis. Sr isotope and major element data suggest that this dolomitizing fluid had a modified seawater origin. The {delta}{sup 13}C values of sandstone intervals from three locations in the central portion of the Michigan basin range from -9 to -4% and are relatively invariant at a particular locality; therefore, the TDC of the dolomitizing fluid in the central Michigan basin is interpreted to have contained only about 20-30% organic carbon. The fact that all dolomites analyzed in the St. Peter Sandstone have much lower {Delta}{sup 13}C values that carbonates in adjacent formations indicates that dolomitization and the formation of hydraulic seals were related to organic matter diagenesis.« less

  19. Coal-type gas provinces in China and their geochemical characteristics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang Xiaobao; Xu Yonghang; Shen Ping

    1996-12-31

    The distribution of coal - type gases in China can be divided into the east gas province, the central gas province and the west gas province the east gas province lies in the East China Meso - Cenozoic Rift Belt, including Donghai Basin and Bohaiwan Basin. The ages of gas source rocks are Carbo - Permian and Tertiary. The types of gas reservoirs are a anticline or a hidden mountain - fault block combination reservoir. The CH{sub 4} content ofthe gases there is 83 -90%, with {delta}{sup 13}C{sub 1} -35.5 {approximately} -39.9{per_thousand}, and {delta}{sup 13}C{sub 2} -24.0 {approximately} -26.8{per_thousand}. Themore » {delta}{sup 13}C of condensate oils associated with the gases ranges from -25.4{per_thousand} to -26.8{per_thousand}. The central gas province is inside the Central China Paleozoic Plates, including Orclos Basin and Sichuan Basin. The gas source rocks are Carbo - Permian and Triassic. The types of gas reservoirs are an anticline-fault combination or a lithological-tectonic combination reservoir. The {delta}{sup 13}C{sub 1} of the gases there is -37.9 {approximately} -37. l{per_thousand}, with the {delta}{sup 13}C of condensate oil accompanying them - 25.1 {approximately} -26.6{per_thousand}. The west gas province is within the West China Late Paleozoic Intracontinental Compressive Belt, including Tarim Basin, Jungar Basin and Tuna Basin. The age of gas source rocks is Jurassic. The types of gas reservoirs are an anticline or an anticline-fault reservoir. The CH{sub 4} content of the gases there varies from 60 to 90%, with {delta}{sup 13}C{sub 1} from - 38.7 to -43.7{per_thousand} and {delta} {sup 13}C{sub 2} from -25.9{per_thousand} to -29.9{per_thousand}. The {delta} {sup 13}C of light oils and condensate oils accompanying the gases changes from 24.3{per_thousand} to 27.8{per_thousand}.« less

  20. Coal-type gas provinces in China and their geochemical characteristics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang Xiaobao; Xu Yonghang; Shen Ping

    1996-01-01

    The distribution of coal - type gases in China can be divided into the east gas province, the central gas province and the west gas province the east gas province lies in the East China Meso - Cenozoic Rift Belt, including Donghai Basin and Bohaiwan Basin. The ages of gas source rocks are Carbo - Permian and Tertiary. The types of gas reservoirs are a anticline or a hidden mountain - fault block combination reservoir. The CH[sub 4] content ofthe gases there is 83 -90%, with [delta][sup 13]C[sub 1] -35.5 [approximately] -39.9[per thousand], and [delta][sup 13]C[sub 2] -24.0 [approximately] -26.8[permore » thousand]. The [delta][sup 13]C of condensate oils associated with the gases ranges from -25.4[per thousand] to -26.8[per thousand]. The central gas province is inside the Central China Paleozoic Plates, including Orclos Basin and Sichuan Basin. The gas source rocks are Carbo - Permian and Triassic. The types of gas reservoirs are an anticline-fault combination or a lithological-tectonic combination reservoir. The [delta][sup 13]C[sub 1] of the gases there is -37.9 [approximately] -37. l[per thousand], with the [delta][sup 13]C of condensate oil accompanying them - 25.1 [approximately] -26.6[per thousand]. The west gas province is within the West China Late Paleozoic Intracontinental Compressive Belt, including Tarim Basin, Jungar Basin and Tuna Basin. The age of gas source rocks is Jurassic. The types of gas reservoirs are an anticline or an anticline-fault reservoir. The CH[sub 4] content of the gases there varies from 60 to 90%, with [delta][sup 13]C[sub 1] from - 38.7 to -43.7[per thousand] and [delta] [sup 13]C[sub 2] from -25.9[per thousand] to -29.9[per thousand]. The [delta] [sup 13]C of light oils and condensate oils accompanying the gases changes from 24.3[per thousand] to 27.8[per thousand].« less

  1. Sensory Afferents Use Different Coding Strategies for Heat and Cold.

    PubMed

    Wang, Feng; Bélanger, Erik; Côté, Sylvain L; Desrosiers, Patrick; Prescott, Steven A; Côté, Daniel C; De Koninck, Yves

    2018-05-15

    Primary afferents transduce environmental stimuli into electrical activity that is transmitted centrally to be decoded into corresponding sensations. However, it remains unknown how afferent populations encode different somatosensory inputs. To address this, we performed two-photon Ca 2+ imaging from thousands of dorsal root ganglion (DRG) neurons in anesthetized mice while applying mechanical and thermal stimuli to hind paws. We found that approximately half of all neurons are polymodal and that heat and cold are encoded very differently. As temperature increases, more heating-sensitive neurons are activated, and most individual neurons respond more strongly, consistent with graded coding at population and single-neuron levels, respectively. In contrast, most cooling-sensitive neurons respond in an ungraded fashion, inconsistent with graded coding and suggesting combinatorial coding, based on which neurons are co-activated. Although individual neurons may respond to multiple stimuli, our results show that different stimuli activate distinct combinations of diversely tuned neurons, enabling rich population-level coding. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

  2. Transfer Learning to Accelerate Interface Structure Searches

    NASA Astrophysics Data System (ADS)

    Oda, Hiromi; Kiyohara, Shin; Tsuda, Koji; Mizoguchi, Teruyasu

    2017-12-01

    Interfaces have atomic structures that are significantly different from those in the bulk, and play crucial roles in material properties. The central structures at the interfaces that provide properties have been extensively investigated. However, determination of even one interface structure requires searching for the stable configuration among many thousands of candidates. Here, a powerful combination of machine learning techniques based on kriging and transfer learning (TL) is proposed as a method for unveiling the interface structures. Using the kriging+TL method, thirty-three grain boundaries were systematically determined from 1,650,660 candidates in only 462 calculations, representing an increase in efficiency over conventional all-candidate calculation methods, by a factor of approximately 3,600.

  3. Earth observations taken from Mir Space Station during NASA 7 mission

    NASA Image and Video Library

    2016-08-29

    NASA7-726-049 (May 1998) --- This view of a sunrise was taken as the Russia's Mir Space Station was on a descending track toward Johnston Island, in the central Pacific (18.1 degrees north latitude and 176.6 degrees west longitude). Sunrises and sunsets are seen by the astronauts and cosmonauts approximately every 45 minutes and differ in structure, since the tropopause altitude and atmospheric lamina temperatures vary with time of day, season, and latitude. From accounts by the astronauts, true replication of human vision is not possible using present film. Some have said there are many more layers in the atmosphere than what the film is recording.

  4. Radial flow in 40Ar+45Sc reactions at E=35-115 MeV/nucleon

    NASA Astrophysics Data System (ADS)

    Pak, R.; Craig, D.; Gualtieri, E. E.; Hannuschke, S. A.; Lacey, R. A.; Lauret, J.; Llope, W. J.; Stone, N. T. B.; Vander Molen, A. M.; Westfall, G. D.; Yee, J.

    1996-10-01

    Collective radial flow of light fragments from 40Ar+45Sc reactions at beam energies between 35 and 115 MeV/nucleon has been investigated using the Michigan State University 4π Array. The mean transverse kinetic energy of the different fragment types increases with event centrality and increases as a function of the incident beam energy. Comparison of our measured values of shows agreement with predictions of Boltzmann-Uehling-Uhlenbeck model and WIX multifragmentation model calculations. The radial flow extracted from accounts for approximately half of the emitted particle's energy for the heavier fragments (Z>=4) at the highest beam energy studied.

  5. A Different Point of View towards GRB 031203

    NASA Technical Reports Server (NTRS)

    Ramirez-Ruiz, E.; Granot, J.; Kouveliotou, C.; Woosley, S. E.; Patel, S. K.; Mazzali, P. A.

    2004-01-01

    One of the most fundamental characteristics of any explosion is its energy, yet despite lively debates, the gamma-ray burst (GRB) community has still to reach a consensus on whether GRBs are standard bombs with a total energy in their relativistic ejecta approximately 10(exp 51) ergs, or a broad range of phenomena with energies varying by many orders of magnitude. While low energy GRBs may well exist, we show here that observations of GRB 031203, do not require a sub-energetic nature for that event. In fact, contrary to previous claims, the data are more consistent with a typical, powerful GRB seen at an angle of about twice the opening angle of the central jet.

  6. Flux splitting algorithms for two-dimensional viscous flows with finite-rate chemistry

    NASA Technical Reports Server (NTRS)

    Shuen, Jian-Shun; Liou, Meng-Sing

    1989-01-01

    The Roe flux difference splitting method was extended to treat 2-D viscous flows with nonequilibrium chemistry. The derivations have avoided unnecessary assumptions or approximations. For spatial discretization, the second-order Roe upwind differencing is used for the convective terms and central differencing for the viscous terms. An upwind-based TVD scheme is applied to eliminate oscillations and obtain a sharp representation of discontinuities. A two-state Runge-Kutta method is used to time integrate the discretized Navier-Stokes and species transport equations for the asymptotic steady solutions. The present method is then applied to two types of flows: the shock wave/boundary layer interaction problems and the jet in cross flows.

  7. Flux splitting algorithms for two-dimensional viscous flows with finite-rate chemistry

    NASA Technical Reports Server (NTRS)

    Shuen, Jian-Shun; Liou, Meng-Sing

    1989-01-01

    The Roe flux-difference splitting method has been extended to treat two-dimensional viscous flows with nonequilibrium chemistry. The derivations have avoided unnecessary assumptions or approximations. For spatial discretization, the second-order Roe upwind differencing is used for the convective terms and central differencing for the viscous terms. An upwind-based TVD scheme is applied to eliminate oscillations and obtain a sharp representation of discontinuities. A two-stage Runge-Kutta method is used to time integrate the discretized Navier-Stokes and species transport equations for the asymptotic steady solutions. The present method is then applied to two types of flows: the shock wave/boundary layer interaction problems and the jet in cross flows.

  8. Comparison between two scalar field models using rotation curves of spiral galaxies

    NASA Astrophysics Data System (ADS)

    Fernández-Hernández, Lizbeth M.; Rodríguez-Meza, Mario A.; Matos, Tonatiuh

    2018-04-01

    Scalar fields have been used as candidates for dark matter in the universe, from axions with masses ∼ 10-5eV until ultra-light scalar fields with masses ∼ Axions behave as cold dark matter while the ultra-light scalar fields galaxies are Bose-Einstein condensate drops. The ultra-light scalar fields are also called scalar field dark matter model. In this work we study rotation curves for low surface brightness spiral galaxies using two scalar field models: the Gross-Pitaevskii Bose-Einstein condensate in the Thomas-Fermi approximation and a scalar field solution of the Klein-Gordon equation. We also used the zero disk approximation galaxy model where photometric data is not considered, only the scalar field dark matter model contribution to rotation curve is taken into account. From the best-fitting analysis of the galaxy catalog we use, we found the range of values of the fitting parameters: the length scale and the central density. The worst fitting results (values of χ red2 much greater than 1, on the average) were for the Thomas-Fermi models, i.e., the scalar field dark matter is better than the Thomas- Fermi approximation model to fit the rotation curves of the analysed galaxies. To complete our analysis we compute from the fitting parameters the mass of the scalar field models and two astrophysical quantities of interest, the dynamical dark matter mass within 300 pc and the characteristic central surface density of the dark matter models. We found that the value of the central mass within 300 pc is in agreement with previous reported results, that this mass is ≈ 107 M ⊙/pc2, independent of the dark matter model. And, on the contrary, the value of the characteristic central surface density do depend on the dark matter model.

  9. Deep-etch visualization of proteins involved in clathrin assembly

    PubMed Central

    1988-01-01

    Assembly proteins were extracted from bovine brain clathrin-coated vesicles with 0.5 M Tris and purified by clathrin-Sepharose affinity chromatography, then adsorbed to mica and examined by freeze-etch electron microscopy. The fraction possessing maximal ability to promote clathrin polymerization, termed AP-2, was found to be a tripartite structure composed of a relatively large central mass flanked by two smaller mirror-symmetric appendages. Elastase treatment quantitatively removed the appendages and clipped 35 kD from the molecule's major approximately 105-kD polypeptides, indicating that the appendages are made from portions of these polypeptides. The remaining central masses no longer promote clathrin polymerization, suggesting that the appendages are somehow involved in the clathrin assembly reaction. The central masses are themselves relatively compact and brick-shaped, and are sufficiently large to contain two copies of the molecule's other major polypeptides (16- and 50-kD), as well as two copies of the approximately 70-kD protease-resistant portions of the major approximately 105-kD polypeptides. Thus the native molecule seems to be a dimeric, bilaterally symmetrical entity. Direct visualization of AP-2 binding to clathrin was accomplished by preparing mixtures of the two molecules in buffers that marginally inhibit AP-2 aggregation and cage assembly. This revealed numerous examples of AP-2 molecules binding to the so-called terminal domains of clathrin triskelions, consistent with earlier electron microscopic evidence that in fully assembled cages, the AP's attach centrally to inwardly-directed terminal domains of the clathrin molecule. This would place AP-2s between the clathrin coat and the enclosed membrane in whole coated vesicles. AP-2s linked to the membrane were also visualized by enzymatically removing the clathrin from brain coated vesicles, using purified 70 kD, uncoating ATPase plus ATP. This revealed several brick-shaped molecules attached to the vesicle membrane by short stalks. The exact stoichiometry of APs to clathrin in such vesicles, before and after uncoating, remains to be determined. PMID:3417785

  10. Earth Observations taken by the Expedition 27 Crew

    NASA Image and Video Library

    2011-03-16

    ISS027-E-005274 (16 March 2011) --- Central Tien Shan in the People?s Republic of China is featured in this image photographed by an Expedition 27 crew member on the International Space Station (ISS). The Tien Shan (or ?celestial mountains? in Chinese) is one of the largest continuous mountain ranges in the world, extending approximately 2,500 kilometers roughly east-west across Central Asia. This photograph provides a detailed view of part of the central Tien Shan, located approximately 64 kilometers east of a point where the borders of China, Kyrgyzstan, and Kazakhstan meet. While the image looks like it might have been taken from an airplane, it was taken from the space station at an altitude of 341 kilometers. The distance between the ISS ground track position (approximately 304 kilometers to the southwest) and the imaged area produces an oblique ? looking outwards an angle, rather than straight down ? view that, together with shadowing of valleys, accentuates the mountainous topography. Like the Himalayas to the south, the uplift of the Tien Shan results from the ongoing collision between the Eurasian and Indian continental tectonic plates. The rugged topography of the range is the result of subsequent erosion by water, wind, and in the highest parts of the range, active glaciers. Two types of glaciers are visible in the image; cirque glaciers occupy amphitheater-like depressions on the upper slopes of the mountains, and feed ice downslope to aggregate into large valley glaciers such as the one visible at center. Low clouds obscure an adjacent valley and glaciers to the north (upper left). Two high peaks of the central Tien Shan are identifiable in the image. Xuelian Feng has a high summit of 6,527 meters above sea level. To the east, the aptly-named Peak 6231 has summit of 6,231 meters above sea level.

  11. The formation of protostellar disks. 2: Disks around intermediate-mass stars

    NASA Technical Reports Server (NTRS)

    Yorke, Harold W.; Bodenheimer, Peter; Laughlin, G.

    1995-01-01

    Hydrodynamical calculations of the evolution of a collapsing, rotating axisymmetric 10 solar masses molecular clump, including the effects of radiative acceleration but without magnetic fields, are represented. The initial cloud is assumed to be uniformly rotating, centrally condensed sphere with rho is proportional to r(exp -2). Several cases are considered, in which both the overall clump size and the total amount of angular momentum are varied. The calculations show how a warm, quasi-hydrostatic disk surrounding a central unresolved core of only a few solar masses forms and grows in size and mass. The disk is encased in two distinct accretion shock fronts, both of which are several scale heights above the equatorial plane. At the end of the calculation of our standard case, the central unresolved region is found to have a mass of 2.7 solar masses and a ratio of rotational to gravitational energy of approximately 0.45, sufficiently large to be unstable to nonaxisymmetric perturbations. In addition, the inner portions of the disk containing most of the mass are unstable according to the local Toomre criterion, implying that also in this region nonaxisymmetric perturbations will lead to rapid evolution. Under the assumption that gravitational torques would transport angular momentum out of this region, a central core of less than or approximately 8 solar masses with a stable disk of greater than or approximately = 2 solar masses should result. Frequency-dependent radiative transfer calculations of the standard case at selected ages show how the continuum spectrum of the structure depends on the disk's orientation and age and how the observed isophotal contours vary with wavelength. Because of the strong dependence on viewing angle, continuum spectra alone should not be used to estimate the evolutionary stage of development of these objects. Comparable results were obtained for the other cases considered.

  12. Annual water-resources review, White Sands Missile Range, New Mexico

    USGS Publications Warehouse

    Cruz, R.R.

    1982-01-01

    Ground-water data were collected in 1981 at White Sands Missile Range in south-central New Mexico. The total amount of water pumped at White Sands Missile Range was approximately 59 million gallons less than in 1980; however the five supply wells in the Range areas adjacent to the Post Headquarters area produced approximately 16.2 million gallons more in 1981 than in 1980. Depth-to-water measurements in the Post Headquarters supply wells continued to show seasonal declines. (USGS)

  13. Environmental Assessment for Construction at US Central Command Headquarters Complex MacDill AFB, Florida

    DTIC Science & Technology

    2005-12-01

    facility would cover approximately 85,000 square-feet, which would include an approximately 15,000 square-foot auditorium wing . The entire JICCENT...1992. US Air Force, 1986. From the 1940s to Now … A Historical Synopsis of the 56th Tactical Training Wing … and MacDill Air Force Base, Florida...leucocephalus T T Wood stork Mycteria americana E E Brown pelican Pelecanus occidentalis - sse Least tern Sterna antillarum - T Roseate tern Sterna dou!{alii

  14. Controller partitioning for integrated flight/propulsion control implementation

    NASA Technical Reports Server (NTRS)

    Garg, Sanjay

    1993-01-01

    The notion of partitioning a centralized controller into a decentralized, hierarchical structure suitable for integrated flight/propulsion control (IFPC) implementation is discussed. A systematic procedure is developed for determining partitioned airframe and engine subsystem controllers (subcontrollers), with the desired interconnection structure, that approximate the closed-loop performance and robustness characteristics of a given centralized controller. The procedure is demonstrated by application to IFPC design for a Short Take-Off and Vertical Landing (STOVL) aircraft in the landing approach to hover transition flight phase.

  15. KSC-04pd1902

    NASA Image and Video Library

    2004-09-22

    KENNEDY SPACE CENTER, FLA. - Workers attempt to secure the roof of the Tile Shop in the Thermal Protection System Facility (TPSF) in preparation for Hurricane Jeanne, which is expected to impact Central Florida Sunday. The TPSF, which creates the TPS tiles, blankets and all the internal thermal control systems for the Space Shuttles, lost approximately 35 percent of its roof during Hurricane Frances, which blew across Central Florida Sept. 4. Jeanne is the fourth hurricane in 45 days to make landfall somewhere in the state.

  16. Antiproton production in central Si+Au collisions at 14.6A GeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rothschild, P.J.

    1994-05-01

    Antiproton measurements made by E802 have been extended to lower rapidities, while in those y-p{sub T} regions already studied the statistics have been improved by approximately an order of magnitude. The author presents the dn/dy distribution for antiproton production in central 14.6 A{center_dot}GeV/c Si+Au collisions in the rapidity range 0.8 < y < 1.8. In addition, antilambda production has been detected for the first time in these collisions at the AGS.

  17. UX Tau A Artist Concept

    NASA Image and Video Library

    2007-11-28

    This artist concept is of the one-million-year-old star system called UX Tau A, approximately 450 light-years away. NASA Spitzer Space Telescope showed a gap in the dusty planet-forming disk swirling around the system central sun-like star.

  18. A Subsonic Aircraft Design Optimization With Neural Network and Regression Approximators

    NASA Technical Reports Server (NTRS)

    Patnaik, Surya N.; Coroneos, Rula M.; Guptill, James D.; Hopkins, Dale A.; Haller, William J.

    2004-01-01

    The Flight-Optimization-System (FLOPS) code encountered difficulty in analyzing a subsonic aircraft. The limitation made the design optimization problematic. The deficiencies have been alleviated through use of neural network and regression approximations. The insight gained from using the approximators is discussed in this paper. The FLOPS code is reviewed. Analysis models are developed and validated for each approximator. The regression method appears to hug the data points, while the neural network approximation follows a mean path. For an analysis cycle, the approximate model required milliseconds of central processing unit (CPU) time versus seconds by the FLOPS code. Performance of the approximators was satisfactory for aircraft analysis. A design optimization capability has been created by coupling the derived analyzers to the optimization test bed CometBoards. The approximators were efficient reanalysis tools in the aircraft design optimization. Instability encountered in the FLOPS analyzer was eliminated. The convergence characteristics were improved for the design optimization. The CPU time required to calculate the optimum solution, measured in hours with the FLOPS code was reduced to minutes with the neural network approximation and to seconds with the regression method. Generation of the approximators required the manipulation of a very large quantity of data. Design sensitivity with respect to the bounds of aircraft constraints is easily generated.

  19. Documentation of computer program VS2D to solve the equations of fluid flow in variably saturated porous media

    USGS Publications Warehouse

    Lappala, E.G.; Healy, R.W.; Weeks, E.P.

    1987-01-01

    This report documents FORTRAN computer code for solving problems involving variably saturated single-phase flow in porous media. The flow equation is written with total hydraulic potential as the dependent variable, which allows straightforward treatment of both saturated and unsaturated conditions. The spatial derivatives in the flow equation are approximated by central differences, and time derivatives are approximated either by a fully implicit backward or by a centered-difference scheme. Nonlinear conductance and storage terms may be linearized using either an explicit method or an implicit Newton-Raphson method. Relative hydraulic conductivity is evaluated at cell boundaries by using either full upstream weighting, the arithmetic mean, or the geometric mean of values from adjacent cells. Nonlinear boundary conditions treated by the code include infiltration, evaporation, and seepage faces. Extraction by plant roots that is caused by atmospheric demand is included as a nonlinear sink term. These nonlinear boundary and sink terms are linearized implicitly. The code has been verified for several one-dimensional linear problems for which analytical solutions exist and against two nonlinear problems that have been simulated with other numerical models. A complete listing of data-entry requirements and data entry and results for three example problems are provided. (USGS)

  20. Experimental studies in natural groundwater-recharge dynamics: The analysis of observed recharge events

    USGS Publications Warehouse

    Sophocleous, M.; Perry, C.A.

    1985-01-01

    The amounts and time distribution of groundwater recharge from precipitation over an approximately 19-month period were investigated at two instrumented sites in south-central Kansas. Precipitation and evapotranspiration sequences, soil-moisture profiles and storage changes, water fluxes in the unsaturated zone and hydraulic gradients in the saturated zone at various depths, soil temperatures, water-table hydrographs, and water-level changes in nearby wells clearly depict the recharge process. Antecedent moisture conditions and the thickness and nature of the unsaturated zone were found to be the major factors affecting recharge. Although the two instrumented sites are located in sand-dune environments in areas characterized by shallow water table and subhumid continental climate, a significant difference was observed in the estimated effective recharge. The estimates ranged from less than 2.5 to approximately 154 mm at the two sites from February to June 1983. The main reasons for this large difference in recharge estimates were the greater thickness of the unsaturated zone and the lower moisture content in that zone resulting from lower precipitation and higher potential evapotranspiration for one of the sites. Effective recharge took place only during late winter and spring. No summer or fall recharge was observed at either site during the observation period of this study. ?? 1985.

  1. Behavioural characterisation of the alpha-mannosidosis guinea pig.

    PubMed

    Robinson, A J; Crawley, A C; Auclair, D; Weston, P F; Hirte, C; Hemsley, K M; Hopwood, J J

    2008-01-25

    alpha-Mannosidosis is a lysosomal storage disorder resulting from a functional deficiency of the lysosomal enzyme alpha-mannosidase. This deficiency results in the accumulation of various oligosaccharides in the lysosomes of affected individuals, causing somatic pathology and progressive neurological degeneration that results in cognitive deficits, ataxia, and other neurological symptoms. We have a naturally occurring guinea pig model of this disease which exhibits a deficiency of lysosomal alpha-mannosidase and has a similar clinical presentation to human alpha-mannosidosis. Various tests were developed in the present study to characterise and quantitate the loss of neurological function in alpha-mannosidosis guinea pigs and to follow closely the progression of the disease. General neurological examinations showed progressive differences in alpha-mannosidosis animals from approximately 1 month of age. Significant differences were observed in hind limb gait width from 2 months of age and significant cognitive (memory and learning) deficits were observed from 3 months of age. Evoked response tests showed an increase in somatosensory P1 peak latency in alpha-mannosidosis guinea pigs from approximately 2 months of age, as well as progressive hearing loss using auditory brainstem evoked responses. The alpha-mannosidosis guinea pig therefore appears to exhibit many of the characteristics of the human disease, and will be useful in evaluating therapies for treatment of central nervous system pathology.

  2. Evidence of a Cooler Continental Climate in East China during the Warm Early Cenozoic

    PubMed Central

    Zhang, Qian-Qian; Smith, Thierry; Yang, Jian; Li, Cheng-Sen

    2016-01-01

    The early Cenozoic was characterized by a very warm climate especially during the Early Eocene. To understand climatic changes in eastern Asia, we reconstructed the Early Eocene vegetation and climate based on palynological data of a borehole from Wutu coal mine, East China and evaluated the climatic differences between eastern Asia and Central Europe. The Wutu palynological assemblages indicated a warm temperate vegetation succession comprising mixed needle- and broad-leaved forests. Three periods of vegetation succession over time were recognized. The changes of palynomorph relative abundance indicated that period 1 was warm and humid, period 2 was relatively warmer and wetter, and period 3 was cooler and drier again. The climatic parameters estimated by the coexistence approach (CA) suggested that the Early Eocene climate in Wutu was warmer and wetter. Mean annual temperature (MAT) was approximately 16°C and mean annual precipitation (MAP) was 800–1400 mm. Comparison of the Early Eocene climatic parameters of Wutu with those of 39 other fossil floras of different age in East China, reveals that 1) the climate became gradually cooler during the last 65 million years, with MAT dropping by 9.3°C. This cooling trend coincided with the ocean temperature changes but with weaker amplitude; 2) the Early Eocene climate was cooler in East China than in Central Europe; 3) the cooling trend in East China (MAT dropped by 6.9°C) was gentler than in Central Europe (MAT dropped by 13°C) during the last 45 million years. PMID:27196048

  3. Timing and patterns of diversification in the Neotropical bat genus Pteronotus (Mormoopidae).

    PubMed

    Pavan, Ana C; Marroig, Gabriel

    2017-03-01

    We investigate the biogeographic processes related to the origin and current patterns of distribution of the extant species of the genus Pteronotus. This clade of insectivorous bats is widely distributed in the Neotropical Region and has recently gone through a taxonomic update which increased more than twice its diversity. Using six molecular markers of 15 Pteronotus lineages ranging from Mexico to Central Brazil, we reconstruct a time-calibrated tree and infer molecular evolutionary rates for this bat genus. In addition, estimates of range evolution across phylogeny were obtained through statistical model testing among six different biogeographic models. The origin of the genus Pteronotus occurred approximately 16million years ago (Ma), with initial cladogenesis events being evenly distributed across the phylogeny. Divergence between most closely related species is recent, falling in the Pleistocene period less than 2.6Ma. Mainland lineages present congruent patterns of north versus south continent splitting while insular clades differ in their time of arrival in the Caribbean Islands. Temporal and geographic range estimates for early nodes of Pteronotus phylogeny suggest a central role of Neogene tectonic reorganizations of Central America in the group diversification process. Also, South American colonization by Pteronotus occurred early in the genus history. Founder-event speciation was an important mode of lineage splitting in Pteronotus, with two independent dispersal jumps having occurred to the Greater Antilles. Finally, Pleistocenic sea-level variation and climatic oscillations are possibly associated with divergence between sister-species and recent ages of MRCA for Pteronotus species. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Evidence of a Cooler Continental Climate in East China during the Warm Early Cenozoic.

    PubMed

    Zhang, Qian-Qian; Smith, Thierry; Yang, Jian; Li, Cheng-Sen

    2016-01-01

    The early Cenozoic was characterized by a very warm climate especially during the Early Eocene. To understand climatic changes in eastern Asia, we reconstructed the Early Eocene vegetation and climate based on palynological data of a borehole from Wutu coal mine, East China and evaluated the climatic differences between eastern Asia and Central Europe. The Wutu palynological assemblages indicated a warm temperate vegetation succession comprising mixed needle- and broad-leaved forests. Three periods of vegetation succession over time were recognized. The changes of palynomorph relative abundance indicated that period 1 was warm and humid, period 2 was relatively warmer and wetter, and period 3 was cooler and drier again. The climatic parameters estimated by the coexistence approach (CA) suggested that the Early Eocene climate in Wutu was warmer and wetter. Mean annual temperature (MAT) was approximately 16°C and mean annual precipitation (MAP) was 800-1400 mm. Comparison of the Early Eocene climatic parameters of Wutu with those of 39 other fossil floras of different age in East China, reveals that 1) the climate became gradually cooler during the last 65 million years, with MAT dropping by 9.3°C. This cooling trend coincided with the ocean temperature changes but with weaker amplitude; 2) the Early Eocene climate was cooler in East China than in Central Europe; 3) the cooling trend in East China (MAT dropped by 6.9°C) was gentler than in Central Europe (MAT dropped by 13°C) during the last 45 million years.

  5. Variation of Cone Photoreceptor Packing Density with Retinal Eccentricity and Age

    PubMed Central

    Song, Hongxin; Chui, Toco Yuen Ping; Zhong, Zhangyi; Elsner, Ann E.

    2011-01-01

    Purpose. To study the variation of cone photoreceptor packing density across the retina in healthy subjects of different ages. Methods. High-resolution adaptive optics scanning laser ophthalmoscope (AOSLO) systems were used to systematically image the retinas of two groups of subjects of different ages. Ten younger subjects (age range, 22–35 years) and 10 older subjects (age range, 50–65 years) were tested. Strips of cone photoreceptors, approximately 12° × 1.8° long were imaged for each of the four primary retinal meridians: superior, inferior, nasal, and temporal. Cone photoreceptors within the strips were counted, and cone photoreceptor packing density was calculated. Statistical analysis (three-way ANOVA) was used to calculate the interaction for cone photoreceptor packing density between age, meridian, and eccentricity. Results. As expected, cone photoreceptor packing density was higher close to the fovea and decreased with increasing retinal eccentricity from 0.18 to 3.5 mm (∼0.6–12°). Older subjects had approximately 75% of the cone density at 0.18 mm (∼0.6°), and this difference decreased rapidly with eccentricity, with the two groups having similar cone photoreceptor packing densities beyond 0.5 mm retinal eccentricity on average. Conclusions. Cone packing density in the living human retina decreases as a function of age within the foveal center with the largest difference being found at our most central measurement site. At all ages, the retina showed meridional difference in cone densities, with cone photoreceptor packing density decreasing faster with increasing eccentricity in the vertical dimensions than in the horizontal dimensions. PMID:21724911

  6. Variation of cone photoreceptor packing density with retinal eccentricity and age.

    PubMed

    Song, Hongxin; Chui, Toco Yuen Ping; Zhong, Zhangyi; Elsner, Ann E; Burns, Stephen A

    2011-09-01

    To study the variation of cone photoreceptor packing density across the retina in healthy subjects of different ages. High-resolution adaptive optics scanning laser ophthalmoscope (AOSLO) systems were used to systematically image the retinas of two groups of subjects of different ages. Ten younger subjects (age range, 22-35 years) and 10 older subjects (age range, 50-65 years) were tested. Strips of cone photoreceptors, approximately 12° × 1.8° long were imaged for each of the four primary retinal meridians: superior, inferior, nasal, and temporal. Cone photoreceptors within the strips were counted, and cone photoreceptor packing density was calculated. Statistical analysis (three-way ANOVA) was used to calculate the interaction for cone photoreceptor packing density between age, meridian, and eccentricity. As expected, cone photoreceptor packing density was higher close to the fovea and decreased with increasing retinal eccentricity from 0.18 to 3.5 mm (∼0.6-12°). Older subjects had approximately 75% of the cone density at 0.18 mm (∼0.6°), and this difference decreased rapidly with eccentricity, with the two groups having similar cone photoreceptor packing densities beyond 0.5 mm retinal eccentricity on average. Cone packing density in the living human retina decreases as a function of age within the foveal center with the largest difference being found at our most central measurement site. At all ages, the retina showed meridional difference in cone densities, with cone photoreceptor packing density decreasing faster with increasing eccentricity in the vertical dimensions than in the horizontal dimensions.

  7. Mining the protein data bank with CReF to predict approximate 3-D structures of polypeptides.

    PubMed

    Dorn, Márcio; de Souza, Osmar Norberto

    2010-01-01

    n this paper we describe CReF, a Central Residue Fragment-based method to predict approximate 3-D structures of polypeptides by mining the Protein Data Bank (PDB). The approximate predicted structures are good enough to be used as starting conformations in refinement procedures employing state-of-the-art molecular mechanics methods such as molecular dynamics simulations. CReF is very fast and we illustrate its efficacy in three case studies of polypeptides whose sizes vary from 34 to 70 amino acids. As indicated by the RMSD values, our initial results show that the predicted structures adopt the expected fold, similar to the experimental ones.

  8. Optimal partitioning of random programs across two processors

    NASA Technical Reports Server (NTRS)

    Nicol, D. M.

    1986-01-01

    The optimal partitioning of random distributed programs is discussed. It is concluded that the optimal partitioning of a homogeneous random program over a homogeneous distributed system either assigns all modules to a single processor, or distributes the modules as evenly as possible among all processors. The analysis rests heavily on the approximation which equates the expected maximum of a set of independent random variables with the set's maximum expectation. The results are strengthened by providing an approximation-free proof of this result for two processors under general conditions on the module execution time distribution. It is also shown that use of this approximation causes two of the previous central results to be false.

  9. Host–parasite behavioral interactions in a recently introduced, whooping crane population

    USGS Publications Warehouse

    King, Richard S.; McKann, Patrick C.; Gray, Brian R.; Putnam, Michael S.

    2015-01-01

    The whooping crane Grus americana has a long conservation history, but despite multiple attempts across North America, introduction success is lacking. Recently introduced, captively reared whooping cranes have had periods of poor reproductive performance in central Wisconsin that sometimes coincided with black fly (Diptera: Simuliidae) emergences. Sandhill crane Grus canadensis reproductive performance in central Wisconsin is approximately double that of whooping cranes. We used comfort behaviors as a measure of black fly harassment to infer whether behavioral differences existed between nesting sandhill cranes and nesting whooping cranes and between successful and unsuccessful whooping crane pairs. To further explore the interaction between black flies and incubating whooping cranes, we examined differences in behaviors between incubating birds and their off-nest mates. Compared to their off-nest mates, incubating whooping cranes exhibited elevated comfort behaviors, suggesting a bird at a nest may experience greater harassment from black flies. Sandhill cranes had elevated head-flicks over whooping cranes. Whooping cranes exhibited more head-rubs than sandhill cranes, and successful whooping crane pairs had elevated head-rubs over pairs that deserted their nests. Behavioral differences between sandhill cranes and whooping cranes as well as differences in reproductive performance, could be explained by exposure to local breeding conditions. Whereas sandhill cranes have nested in the area for hundreds, if not thousands, of years, whooping cranes were only recently introduced to the area. Behavioral differences between the species as well as those between successful and unsuccessful whooping crane pairs could also be explained by the effect of captive exposure, which could affect all whooping crane introductions.

  10. An electrophysiological index of changes in risk decision-making strategies.

    PubMed

    Zhang, Dandan; Gu, Ruolei; Wu, Tingting; Broster, Lucas S; Luo, Yi; Jiang, Yang; Luo, Yue-jia

    2013-07-01

    Human decision-making is significantly modulated by previously experienced outcomes. Using event-related potentials (ERPs), we examined whether ERP components evoked by outcome feedbacks could serve as biomarkers to signal the influence of current outcome evaluation on subsequent decision-making. In this study, 18 adult volunteers participated in a simple monetary gambling task, in which they were asked to choose between two options that differed in risk. Their decisions were immediately followed by outcome presentation. Temporospatial principle component analysis (PCA) was applied to the outcome-onset locked ERPs in the 200-1000 ms time window. The PCA factors that approximated classical ERP components (P2, feedback-related negativity, P3a, and P3b) in terms of time course and scalp distribution were tested for their association with subsequent decision-making strategies. Our results revealed that a fronto-central PCA factor approximating the classical P3a was related to changes of decision-making strategies on subsequent trials. The decision to switch between high- and low-risk options resulted in a larger P3a relative to the decision to retain the same choice. According to the results, we suggest that the amplitude of the fronto-central P3a is an electrophysiological index of the influence of current outcome on subsequent risk decision-making. Furthermore, the ERP source analysis indicated that the activations of the frontopolar cortex and sensorimotor cortex were involved in subsequent changes of strategies, which enriches our understanding of the neural mechanisms of adjusting decision-making strategies based on previous experience. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Suzaku observations of low surface brightness cluster Abell 1631

    NASA Astrophysics Data System (ADS)

    Babazaki, Yasunori; Mitsuishi, Ikuyuki; Ota, Naomi; Sasaki, Shin; Böhringer, Hans; Chon, Gayoung; Pratt, Gabriel W.; Matsumoto, Hironori

    2018-04-01

    We present analysis results for a nearby galaxy cluster Abell 1631 at z = 0.046 using the X-ray observatory Suzaku. This cluster is categorized as a low X-ray surface brightness cluster. To study the dynamical state of the cluster, we conduct four-pointed Suzaku observations and investigate physical properties of the Mpc-scale hot gas associated with the A 1631 cluster for the first time. Unlike relaxed clusters, the X-ray image shows no strong peak at the center and an irregular morphology. We perform spectral analysis and investigate the radial profiles of the gas temperature, density, and entropy out to approximately 1.5 Mpc in the east, north, west, and south directions by combining with the XMM-Newton data archive. The measured gas density in the central region is relatively low (a few ×10-4 cm-3) at the given temperature (˜2.9 keV) compared with X-ray-selected clusters. The entropy profile and value within the central region (r < 0.1 r200) are found to be flatter and higher (≳400 keV cm2). The observed bolometric luminosity is approximately three times lower than that expected from the luminosity-temperature relation in previous studies of relaxed clusters. These features are also observed in another low surface brightness cluster, Abell 76. The spatial distributions of galaxies and the hot gas appear to be different. The X-ray luminosity is relatively lower than that expected from the velocity dispersion. A post-merger scenario may explain the observed results.

  12. An electrophysiological index of changes in risk decision-making strategies

    PubMed Central

    Zhang, Dandan; Gu, Ruolei; Wu, Tingting; Broster, Lucas S.; Luo, Yi; Jiang, Yang; Luo, Yue-jia

    2014-01-01

    Human decision-making is significantly modulated by previously experienced outcomes. Using event-related potentials (ERPs), we examined whether ERP components evoked by outcome feedbacks could serve as biomarkers to signal the influence of current outcome evaluation on subsequent decision-making. In this study, eighteen adult volunteers participated in a simple monetary gambling task, in which they were asked to choose between two options that differed in risk. Their decisions were immediately followed by outcome presentation. Temporospatial principle component analysis (PCA) was applied to the outcome-onset locked ERPs in the -200 – 1000 ms time window. The PCA factors that approximated classical ERP components (P2, feedback-related negativity, P3a, & P3b) in terms of time course and scalp distribution were tested for their association with subsequent decision-making strategies. Our results revealed that a fronto-central PCA factor approximating the classical P3a was related to changes of decision-making strategies on subsequent trials. The decision to switch between high- and low-risk options resulted in a larger P3a relative to the decision to retain the same choice. According to the results, we suggest the amplitude of the fronto-central P3a is an electrophysiological index of the influence of current outcome on subsequent risk decision-making. Furthermore, the ERP source analysis indicated that the activations of the frontopolar cortex and sensorimotor cortex were involved in subsequent changes of strategies, which enriches our understanding of the neural mechanisms of adjusting decision-making strategies based on previous experience. PMID:23643796

  13. Suzaku observations of low surface brightness cluster Abell 1631

    NASA Astrophysics Data System (ADS)

    Babazaki, Yasunori; Mitsuishi, Ikuyuki; Ota, Naomi; Sasaki, Shin; Böhringer, Hans; Chon, Gayoung; Pratt, Gabriel W.; Matsumoto, Hironori

    2018-06-01

    We present analysis results for a nearby galaxy cluster Abell 1631 at z = 0.046 using the X-ray observatory Suzaku. This cluster is categorized as a low X-ray surface brightness cluster. To study the dynamical state of the cluster, we conduct four-pointed Suzaku observations and investigate physical properties of the Mpc-scale hot gas associated with the A 1631 cluster for the first time. Unlike relaxed clusters, the X-ray image shows no strong peak at the center and an irregular morphology. We perform spectral analysis and investigate the radial profiles of the gas temperature, density, and entropy out to approximately 1.5 Mpc in the east, north, west, and south directions by combining with the XMM-Newton data archive. The measured gas density in the central region is relatively low (a few ×10-4 cm-3) at the given temperature (˜2.9 keV) compared with X-ray-selected clusters. The entropy profile and value within the central region (r < 0.1 r200) are found to be flatter and higher (≳400 keV cm2). The observed bolometric luminosity is approximately three times lower than that expected from the luminosity-temperature relation in previous studies of relaxed clusters. These features are also observed in another low surface brightness cluster, Abell 76. The spatial distributions of galaxies and the hot gas appear to be different. The X-ray luminosity is relatively lower than that expected from the velocity dispersion. A post-merger scenario may explain the observed results.

  14. Testing for shared biogeographic history in the lower Central American freshwater fish assemblage using comparative phylogeography: concerted, independent, or multiple evolutionary responses?

    PubMed Central

    Bagley, Justin C; Johnson, Jerald B

    2014-01-01

    A central goal of comparative phylogeography is determining whether codistributed species experienced (1) concerted evolutionary responses to past geological and climatic events, indicated by congruent spatial and temporal patterns (“concerted-response hypothesis”); (2) independent responses, indicated by spatial incongruence (“independent-response hypothesis”); or (3) multiple responses (“multiple-response hypothesis”), indicated by spatial congruence but temporal incongruence (“pseudocongruence”) or spatial and temporal incongruence (“pseudoincongruence”). We tested these competing hypotheses using DNA sequence data from three livebearing fish species codistributed in the Nicaraguan depression of Central America (Alfaro cultratus, Poecilia gillii, and Xenophallus umbratilis) that we predicted might display congruent responses due to co-occurrence in identical freshwater drainages. Spatial analyses recovered different subdivisions of genetic structure for each species, despite shared finer-scale breaks in northwestern Costa Rica (also supported by phylogenetic results). Isolation-with-migration models estimated incongruent timelines of among-region divergences, with A. cultratus and Xenophallus populations diverging over Miocene–mid-Pleistocene while P. gillii populations diverged over mid-late Pleistocene. Approximate Bayesian computation also lent substantial support to multiple discrete divergences over a model of simultaneous divergence across shared spatial breaks (e.g., Bayes factor [B10] = 4.303 for Ψ [no. of divergences] > 1 vs. Ψ = 1). Thus, the data support phylogeographic pseudoincongruence consistent with the multiple-response hypothesis. Model comparisons also indicated incongruence in historical demography, for example, support for intraspecific late Pleistocene population growth was unique to P. gillii, despite evidence for finer-scale population expansions in the other taxa. Empirical tests for phylogeographic congruence indicate that multiple evolutionary responses to historical events have shaped the population structure of freshwater species codistributed within the complex landscapes in/around the Nicaraguan depression. Recent community assembly through different routes (i.e., different past distributions or colonization routes), and intrinsic ecological differences among species, has likely contributed to the unique phylogeographical patterns displayed by these Neotropical fishes. PMID:24967085

  15. Prevalences of overweight and obesity among children in remote Aboriginal communities in central Australia.

    PubMed

    Schultz, Rosalie

    2012-01-01

    The chronic diseases associated with overweight and obesity are major contributors to the excess disease burden of Aboriginal Australians. Surveillance of overweight and obesity is required to monitor these conditions, and to develop and evaluate interventions to improve health and wellbeing. Remote Aboriginal communities in Australia's Northern Territory (NT) are where approximately two-thirds of the NT Aboriginal people live, a proportion which has been stable over many years. However the remote communities suffer significant socioeconomic disadvantage including limited education and employment opportunities, and poor quality and overcrowded housing. Approximately one-third of Aboriginal people in NT live in central Australia, which consists of the Alice Springs and Barkly districts. The Healthy School-Aged Kids Program includes health promotion and child health screening, and is run in remote Aboriginal communities of NT. This report provides estimates of prevalences of overweight and obesity among children in central Australia who participated in health checks as part of Healthy School-Aged Kids Program in 2010. All children in remote central Australian Aboriginal communities were invited to participate in health checks. Children who attended were weighed and measured. Date of birth, sex, height and weight for each child were used to determine prevalence of overweight (≥+1 standard deviation [SD] BMI-for-age) and obesity (≥+2 SD BMI-for-age) according to WHO Growth standards. Differences in proportions of overweight and obesity by age group and sex, and their statistical significance were calculated. Weight, height, sex and age data were available for 996 children from a population of 1764. It was found that 22.1% of girls and 20.7% of boys were overweight; and 5.1% of girls and 5.8% of boys were obese as defined by BMI-for-age. Prevalence of overweight but not obesity increased with age (for overweight z=3.28, p=0.0011; for obesity z=0.68; p=0.50). The prevalences of overweight and obesity as estimated by BMI-for-age among children in remote central Australian Aboriginal communities were compared with those in other Australian surveys. They appear unlikely to reflect future relative risk of the chronic diseases with which overweight and obesity are associated. Routine collection of data on BMI-for-age may not provide adequate estimation of future risk of chronic disease burden attributable to overweight and obesity among these children. Alternative measures for surveillance for overweight such as waist circumference may prove more useful. Appropriate interventions to reduce risk of chronic disease are required, including interventions to reduce prevalences of overweight and obesity.

  16. One-dimensional model and solutions for creeping gas flows in the approximation of uniform pressure

    NASA Astrophysics Data System (ADS)

    Vedernikov, A.; Balapanov, D.

    2016-11-01

    A model, along with analytical and numerical solutions, is presented to describe a wide variety of one-dimensional slow flows of compressible heat-conductive fluids. The model is based on the approximation of uniform pressure valid for the flows, in which the sound propagation time is much shorter than the duration of any meaningful density variation in the system. The energy balance is described by the heat equation that is solved independently. This approach enables the explicit solution for the fluid velocity to be obtained. Interfacial and volumetric heat and mass sources as well as boundary motion are considered as possible sources of density variation in the fluid. A set of particular tasks is analyzed for different motion sources in planar, axial, and central symmetries in the quasistationary limit of heat conduction (i.e., for large Fourier number). The analytical solutions are in excellent agreement with corresponding numerical solutions of the whole system of the Navier-Stokes equations. This work deals with the ideal gas. The approach is also valid for other equations of state.

  17. Comparison of heaving buoy and oscillating flap wave energy converters

    NASA Astrophysics Data System (ADS)

    Abu Bakar, Mohd Aftar; Green, David A.; Metcalfe, Andrew V.; Najafian, G.

    2013-04-01

    Waves offer an attractive source of renewable energy, with relatively low environmental impact, for communities reasonably close to the sea. Two types of simple wave energy converters (WEC), the heaving buoy WEC and the oscillating flap WEC, are studied. Both WECs are considered as simple energy converters because they can be modelled, to a first approximation, as single degree of freedom linear dynamic systems. In this study, we estimate the response of both WECs to typical wave inputs; wave height for the buoy and corresponding wave surge for the flap, using spectral methods. A nonlinear model of the oscillating flap WEC that includes the drag force, modelled by the Morison equation is also considered. The response to a surge input is estimated by discrete time simulation (DTS), using central difference approximations to derivatives. This is compared with the response of the linear model obtained by DTS and also validated using the spectral method. Bendat's nonlinear system identification (BNLSI) technique was used to analyze the nonlinear dynamic system since the spectral analysis was only suitable for linear dynamic system. The effects of including the nonlinear term are quantified.

  18. Estimation of the cost of large-scale school deworming programmes with benzimidazoles

    PubMed Central

    Montresor, A.; Gabrielli, A.F.; Engels, D.

    2017-01-01

    Summary This study estimates the cost of distributing benzimidazole tablets in the context of school deworming programmes: we analysed studies reporting the cost of school deworming from seven countries in four WHO regions. The estimated cost for drug procurement to cover one million children (including customs clearance and international transport) is approximately US$20 000. The estimated financial costs (including the cost of training of personnel, drug transport, social mobilization and monitoring) is, on average, equivalent to US$33 000 per million school-age children with minimal variation in different countries and continents. The estimated economic costs of distribution (including the time spent by teachers, and health personnel at central, provincial and district level) to cover one million children approximately corresponds to US$19 000. This study shows the minimal cost of school deworming activities, but also shows the significant contribution (corresponding to a quarter of the entire cost of the programme) provided by health and education systems in endemic countries even in the case of drug donations and donor support of distribution costs. PMID:19926104

  19. Essentially nonoscillatory postprocessing filtering methods

    NASA Technical Reports Server (NTRS)

    Lafon, F.; Osher, S.

    1992-01-01

    High order accurate centered flux approximations used in the computation of numerical solutions to nonlinear partial differential equations produce large oscillations in regions of sharp transitions. Here, we present a new class of filtering methods denoted by Essentially Nonoscillatory Least Squares (ENOLS), which constructs an upgraded filtered solution that is close to the physically correct weak solution of the original evolution equation. Our method relies on the evaluation of a least squares polynomial approximation to oscillatory data using a set of points which is determined via the ENO network. Numerical results are given in one and two space dimensions for both scalar and systems of hyperbolic conservation laws. Computational running time, efficiency, and robustness of method are illustrated in various examples such as Riemann initial data for both Burgers' and Euler's equations of gas dynamics. In all standard cases, the filtered solution appears to converge numerically to the correct solution of the original problem. Some interesting results based on nonstandard central difference schemes, which exactly preserve entropy, and have been recently shown generally not to be weakly convergent to a solution of the conservation law, are also obtained using our filters.

  20. The Three-dimensional Structure of the Eta Carinae Homunculus

    NASA Technical Reports Server (NTRS)

    Steffen, W.; Teodoro, M.; Madura, T.I.; Groh, J.H.; Gull, T.R.; Mehner, A.; Corcoran, M.F.; Damineli, A.; Hamaguchi, K.

    2014-01-01

    We investigate, using the modeling code SHAPE, the three-dimensional structure of the bipolar Homunculus nebula surrounding Eta Carinae as mapped by new ESO VLT/X-Shooter observations of the H2 (lambda) = 2.12125 micrometers emission line. Our results reveal for the first time important deviations from the axisymmetric bipolar morphology: 1) circumpolar trenches in each lobe positioned point-symmetrically from the center and 2) offplanar protrusions in the equatorial region from each lobe at longitudinal (approximately 55 degrees) and latitudinal (10 degrees to 20 degrees) distances from the projected apastron direction of the binary orbit. The angular distance between the protrusions (approximately 110 degrees) is similar to the angular extent of each polar trench (approximately 130 degrees) and nearly equal to the opening angle of the wind-wind collision cavity (approximately 110 degrees). As in previous studies, we confirm a hole near the centre of each polar lobe and no detectable near-IR H2 emission from the thin optical skirt seen prominently in visible imagery. We conclude that the interaction between the outflows and/or radiation from the central binary stars and their orientation in space has had, and possibly still has, a strong influence on the Homunculus. This implies that prevailing theoretical models of the Homunculus are incomplete as most assume a single star origin that produces an axisymmetric nebula.We discuss how the newly found features might be related to the Homunculus ejection, the central binary and the interacting stellar winds.

  1. Geology, coal quality, and resources of the Antaramut-Kurtan-Dzoragukh coal field, north-central Armenia

    USGS Publications Warehouse

    Pierce, B.S.; Martirosyan, A.; Malkhasian, G.; Harutunian, S.; Harutunian, G.

    2001-01-01

    The Antaramut-Kurta-Dzoragukh (AKD) coal deposit is a previously unrecognized coal field in north-central Armenia. Coal has been known to exist in the general vicinity since the turn of the century, but coal was thought to be restricted to a small (1 km2) area only near the village of Antaramut. However, through detailed field work and exploratory drilling, this coal deposit has been expanded to at least 20 km2, and thus renamed the Antaramut-Kurtan-Dzoragukh coal field, for the three villages that the coal field encompasses. The entire coal-bearing horizon, a series of tuffaceous sandstones, siltstones, and claystones, is approximately 50 m thick. The AKD coal field contains two coal beds, each greater than 1 m thick, and numerous small rider beds, with a total resource of approximately 31,000,000 metric tonnes. The coals are late Eocene in age, high volatile bituminous in rank, relatively high in ash yield (approximately 40%, as-determined basis) and moderate in sulfur content (approximately 3%, as-determined basis). The two coal beds (No. 1 and No. 2), on a moist, mineral-matter-free basis, have high calorific values of 32.6 MJ/kg (7796 cal/g) and 36.0 MJ/kg (8599 cal/g), respectively. Coal is one of the few indigenous fossil fuel resources occurring in Armenia and thus, the AKD coal field could potentially provide fuel for heating and possibly energy generation in the Armenian energy budget. Published by Elsevier Science B.V.

  2. Lutzomyia umbratilis, the Main Vector of Leishmania guyanensis, Represents a Novel Species Complex?

    PubMed Central

    Scarpassa, Vera Margarete; Alencar, Ronildo Baiatone

    2012-01-01

    Background Lutzomyia umbratilis is an important Leishmania guyanensis vector in South America. Previous studies have suggested differences in the vector competence between L. umbratilis populations situated on opposite banks of the Amazonas and Negro Rivers in the central Amazonian Brazil region, likely indicating a species complex. However, few studies have been performed on these populations and the taxonomic status of L. umbratilis remains unclear. Methodology/Principal Findings Phylogeographic structure was estimated for six L. umbratilis samples from the central Amazonian region in Brazil by analyzing mtDNA using 1181 bp of the COI gene to assess whether the populations on opposite banks of these rivers consist of incipient or distinct species. The genetic diversity was fairly high and the results revealed two distinct clades ( = lineages) with 1% sequence divergence. Clade I consisted of four samples from the left bank of the Amazonas and Negro Rivers, whereas clade II comprised two samples from the right bank of Negro River. No haplotypes were shared between samples of two clades. Samples within clades exhibited low to moderate genetic differentiation (F ST = −0.0390–0.1841), whereas samples between clades exhibited very high differentiation (F ST = 0.7100–0.8497) and fixed differences. These lineages have diverged approximately 0.22 Mya in the middle Pleistocene. Demographic expansion was detected for the lineages I and II approximately 30,448 and 15,859 years ago, respectively, in the late Pleistocene. Conclusions/Significance The two genetic lineages may represent an advanced speciation stage suggestive of incipient or distinct species within L. umbratilis. These findings suggest that the Amazonas and Negro Rivers may be acting as effective barriers, thus preventing gene flow between populations on opposite sides. Such findings have important implications for epidemiological studies, especially those related to vector competence and anthropophily, and for vector control strategies. In addition, L. umbratilis represents an interesting example in speciation studies. PMID:22662146

  3. Assessment of road users' elemental carbon personal exposure levels, London, UK

    NASA Astrophysics Data System (ADS)

    Adams, H. S.; Nieuwenhuijsen, M. J.; Colvile, R. N.; Older, M. J.; Kendall, M.

    Little is known about particulate elemental carbon (EC) personal exposure levels, a key component of diesel exhaust, specifically in transport microenvironments. A method utilizing the optical properties of EC particles has been applied to personal exposure measurement filter samples. In a series of field studies carried out in London, UK, during 1999-2000 over 400 fine particle (PM 2.5) personal exposure level measurements were taken for journeys in bicycle, bus, car and underground rail transport microenvironments, along three main fixed routes. The particulate EC contribution to the PM 2.5 personal exposure was assessed indirectly by means of an optical technique and with the development and use of a size fraction specific and site-specific calibration curve. In this first EC personal exposure study of transport users geometric mean exposure levels in the summer field campaign were 11.2 μg m -3 (GSD=2.7) for cyclists, 13.6 μg m -3 (GSD=1.9) for bus passengers and 21.6 μg m -3 (GSD=2.1) for car drivers; corresponding exposure levels in the winter were 16.4 μg m -3 (GSD=1.8), 18.6 μg m -3 (GSD=2.3) and 27.3 μg m -3 (GSD=2.0), respectively. EC/PM 2.5 ratios were approximately 0.5-0.6 for bicycle and bus modes and 0.7-0.8 for the car mode. EC/PM 2.5 ratios for different routes ranged from approximately 0.7 for Route 1 to 0.4 for Route 3. Cyclists had the lowest exposure to EC, and car occupants the highest exposure. A large difference in exposure levels between a central high traffic density route and the other less central routes was observed. Particulate EC was a very significant proportion of the total PM 2.5 personal exposure and EC personal exposure levels were considerably higher than reported fixed site monitor EC concentrations.

  4. The Sparta Fault, Southern Greece: From segmentation and tectonic geomorphology to seismic hazard mapping and time dependent probabilities

    NASA Astrophysics Data System (ADS)

    Papanikolaοu, Ioannis D.; Roberts, Gerald P.; Deligiannakis, Georgios; Sakellariou, Athina; Vassilakis, Emmanuel

    2013-06-01

    The Sparta Fault system is a major structure approximately 64 km long that bounds the eastern flank of the Taygetos Mountain front (2407 m) and shapes the present-day Sparta basin. It was activated in 464 B.C., devastating the city of Sparta. This fault is examined and described in terms of its geometry, segmentation, drainage pattern and post-glacial throw, emphasising how these parameters vary along strike. Qualitative analysis of long profile catchments shows a significant difference in longitudinal convexity between the central and both the south and north parts of the fault system, leading to the conclusion of varying uplift rate along strike. Catchments are sensitive in differential uplift as it is observed by the calculated differences of the steepness index ksn between the outer (ksn < 83) and central parts (121 < ksn < 138) of the Sparta Fault along strike the fault system. Based on fault throw-rates and the bedrock geology a seismic hazard map has been constructed that extracts a locality specific long-term earthquake recurrence record. Based on this map the town of Sparta would experience a destructive event similar to that in 464 B.C. approximately every 1792 ± 458 years. Since no other major earthquake M ~ 7.0 has been generated by this system since 464 B.C., a future event could be imminent. As a result, not only time-independent but also time-dependent probabilities, which incorporate the concept of the seismic cycle, have been calculated for the town of Sparta, showing a considerably higher time-dependent probability of 3.0 ± 1.5% over the next 30 years compared to the time-independent probability of 1.66%. Half of the hanging wall area of the Sparta Fault can experience intensities ≥ IX, but belongs to the lowest category of seismic risk of the national seismic building code. On view of these relatively high calculated probabilities, a reassessment of the building code might be necessary.

  5. The Sparta Fault, Southern Greece: From Segmentation and Tectonic Geomorphology to Seismic Hazard Mapping and Time Dependent Probabilities

    NASA Astrophysics Data System (ADS)

    Papanikolaou, Ioannis; Roberts, Gerald; Deligiannakis, Georgios; Sakellariou, Athina; Vassilakis, Emmanuel

    2013-04-01

    The Sparta Fault system is a major structure approximately 64 km long that bounds the eastern flank of the Taygetos Mountain front (2.407 m) and shapes the present-day Sparta basin. It was activated in 464 B.C., devastating the city of Sparta. This fault is examined and described in terms of its geometry, segmentation, drainage pattern and postglacial throw, emphasizing how these parameters vary along strike. Qualitative analysis of long profile catchments shows a significant difference in longitudinal convexity between the central and both the south and north parts of the fault system, leading to the conclusion of varying uplift rate along strike. Catchments are sensitive in differential uplift as it is observed by the calculated differences of the steepness index ksn between the outer (ksn<83) and central parts (121

  6. On the Relationship between the Apollo 16 Ancient Regolith Breccias and Feldspathic Fragmental Breccias, and the Composition of the Prebasin Crust in the Central Highlands of the Moon

    NASA Technical Reports Server (NTRS)

    Korotev, Randy L.

    1996-01-01

    Two types of texturally and compositionally similar breccias that consist largely of fragmental debris from meteorite impacts occur at the Apollo 16 lunar site: Feldspathic fragmental breccias (FFBS) and ancient regolith breccias (ARBs). Both types of breccia are composed of a suite of mostly feldspathic components derived from the early crust of the Moon and mafic impact-melt breccias produced during the time of basin formation. The ARBs also contain components, such as agglutinates and glass spherules, indicating that the material of which they are composed occurred at the surface of the Moon as fine-grained regolith prior to lithification of the breccias. These components are absent from the FFBS, suggesting that the FFBs might be the protolith of the ARBS. However, several compositional differences exist between the two types of breccia, making any simple genetic relationship implausible. First, clasts of mafic impact-melt breccia occurring in the FFBs are of a different composition than those in the ARBS. Also the feldspathic "prebasin" components of the FFBs have a lower average Mg/Fe ratio than the corresponding components of the ARBS; the average composition of the plagiociase in the FFBs is more sodic than that of the ARBS; and there are differences in relative abundances of rare earth elements. The two breccia types also have different provenances: the FFBs occur primarily in ejecta from North Ray crater and presumably derive from the Descartes Formation, while the ARBs are restricted to the Cayley plains. Together these observations suggest that although some type of fragmental breccia may have been a precursor to the ARBS, the FFBs of North Ray crater are not a significant component of the ARBs and, by inference, the Cayley plains. The average compositions of the prebasin components of the two types of fragmental breccia are generally similar to the composition of the feldspathic lunar meteorites. With 30-31% Al203, however, they are slightly richer in plagiociase than the most feldspathic lunar meteorites (approximately 29% Al203), implying that the crust of the early central nearside of the Moon contained a higher abundance of highly feldspathic anorthosite than typical lunar highlands, as inferred from the lunar meteorites. The ancient regolith breccias, as well as the current surface regolith ofthe Cayley plains, are more mafic than (1) prebasin regoliths in the Central Highlands and (2) regions of highlands presently distant from nearside basins because they contain a high abundance (approximately 30%) of mafic impact-melt breccias produced during the time of basin formation that is absent from other regoliths.

  7. Near-optimal experimental design for model selection in systems biology.

    PubMed

    Busetto, Alberto Giovanni; Hauser, Alain; Krummenacher, Gabriel; Sunnåker, Mikael; Dimopoulos, Sotiris; Ong, Cheng Soon; Stelling, Jörg; Buhmann, Joachim M

    2013-10-15

    Biological systems are understood through iterations of modeling and experimentation. Not all experiments, however, are equally valuable for predictive modeling. This study introduces an efficient method for experimental design aimed at selecting dynamical models from data. Motivated by biological applications, the method enables the design of crucial experiments: it determines a highly informative selection of measurement readouts and time points. We demonstrate formal guarantees of design efficiency on the basis of previous results. By reducing our task to the setting of graphical models, we prove that the method finds a near-optimal design selection with a polynomial number of evaluations. Moreover, the method exhibits the best polynomial-complexity constant approximation factor, unless P = NP. We measure the performance of the method in comparison with established alternatives, such as ensemble non-centrality, on example models of different complexity. Efficient design accelerates the loop between modeling and experimentation: it enables the inference of complex mechanisms, such as those controlling central metabolic operation. Toolbox 'NearOED' available with source code under GPL on the Machine Learning Open Source Software Web site (mloss.org).

  8. Spontaneous vegetation succession at different central European mining sites: a comparison across seres.

    PubMed

    Prach, Karel; Lencová, Kamila; Rehounková, Klára; Dvořáková, Helena; Jírová, Alena; Konvalinková, Petra; Mudrák, Ondřej; Novák, Jan; Trnková, Romana

    2013-11-01

    We performed detrended correspondence analysis (DCA) ordination to compare seven successional seres running in stone quarries, coal mining spoil heaps, sand and gravel pits, and extracted peatlands in the Czech Republic in central Europe. In total, we obtained 1,187 vegetation samples containing 705 species. These represent various successional stages aged from 1 to 100 years. The successional seres studied were more similar in their species composition in the initial stages, in which synathropic species prevailed, than in later successional stages. This vegetation differentiation was determined especially by local moisture conditions. In most cases, succession led to a woodland, which usually established after approximately 20 years. In very dry or wet places, by contrast, where woody species were limited, often highly valuable, open vegetation developed. Except in the peatlands, the total number of species and the number of target species increased during succession. Participation of invasive aliens was mostly unimportant. Spontaneous vegetation succession generally appears to be an ecologically suitable and cheap way of ecosystem restoration of heavily disturbed sites. It should, therefore, be preferred over technical reclamation.

  9. Titius-Bode laws in the solar system. 2: Build your own law from disk models

    NASA Astrophysics Data System (ADS)

    Dubrulle, B.; Graner, F.

    1994-02-01

    Simply respecting both scale and rotational invariance, it is easy to construct an endless collection of theoretical models predicting a Titius-Bode law, irrespective to their physical content. Due to the numerous ways to get the law and its intrinsic arbitrariness, it is not a useful constraint on theories of solar system formation. To illustrate the simple elegance of scale-invariant methods, we explicitly cook up one of the simplest examples, an infinitely thin cold gaseous disk rotating around a central object. In that academic case, the Titius-Bode law holds during the linear stage of the gravitational instability. The time scale of the instability is of the order of a self-gravitating time scale, (G rhod)-1/2, where rhod is the disk density. This model links the separation between different density maxima with the ratio MD/MC of the masses of the disk and the central object; for instance, MD/MC of the order of 0.18 roughly leads to the observed separation between the planets. We discuss the boundary conditions and the limit of the Wentzel-Kramer-Brillouin (WKB) approximation.

  10. Fermionic halos at finite temperature in AdS/CFT

    NASA Astrophysics Data System (ADS)

    Argüelles, Carlos R.; Grandi, Nicolás E.

    2018-05-01

    We explore the gravitational backreaction of a system consisting in a very large number of elementary fermions at finite temperature, in asymptotically AdS space. We work in the hydrodynamic approximation, and solve the Tolman-Oppenheimer-Volkoff equations with a perfect fluid whose equation of state takes into account both the relativistic effects of the fermionic constituents, as well as its finite temperature effects. We find a novel dense core-diluted halo structure for the density profiles in the AdS bulk, similarly as recently reported in flat space, for the case of astrophysical dark matter halos in galaxies. We further study the critical equilibrium configurations above which the core undergoes gravitational collapse towards a massive black hole, and calculate the corresponding critical central temperatures, for two qualitatively different central regimes of the fermions: the diluted-Fermi case, and the degenerate case. As a probe for the dual CFT, we construct the holographic two-point correlator of a scalar operator with large conformal dimension in the worldline limit, and briefly discuss on the boundary CFT effects at the critical points.

  11. Estimating Planetary Boundary Layer Heights from NOAA Profiler Network Wind Profiler Data

    NASA Technical Reports Server (NTRS)

    Molod, Andrea M.; Salmun, H.; Dempsey, M

    2015-01-01

    An algorithm was developed to estimate planetary boundary layer (PBL) heights from hourly archived wind profiler data from the NOAA Profiler Network (NPN) sites located throughout the central United States. Unlike previous studies, the present algorithm has been applied to a long record of publicly available wind profiler signal backscatter data. Under clear conditions, summertime averaged hourly time series of PBL heights compare well with Richardson-number based estimates at the few NPN stations with hourly temperature measurements. Comparisons with clear sky reanalysis based estimates show that the wind profiler PBL heights are lower by approximately 250-500 m. The geographical distribution of daily maximum PBL heights corresponds well with the expected distribution based on patterns of surface temperature and soil moisture. Wind profiler PBL heights were also estimated under mostly cloudy conditions, and are generally higher than both the Richardson number based and reanalysis PBL heights, resulting in a smaller clear-cloudy condition difference. The algorithm presented here was shown to provide a reliable summertime climatology of daytime hourly PBL heights throughout the central United States.

  12. Impulse responses of visible phototubes used in National Ignition Facility neutron time of flight diagnostics.

    PubMed

    Datte, P S; Eckart, M; Moore, A S; Thompson, W; Vergel de Dios, G

    2016-11-01

    Neutron-induced visible scintillation in neutron time of flight (NToF) diagnostics at the National Ignition Facility (NIF) is measured with 40 mm single stage micro-channel plate photomultipliers and a 40 mm vacuum photodiode, outside the neutron line of sight. In NIF experiments with 14 MeV neutron yields above Y > 10 × 10 15 these tubes are configured to deliver of order 1 nC of charge in the nominally 5 ns NToF into a 50 Ω load. We have examined a number of 40 mm tubes manufactured by Photek Ltd. of St. Leonards on Sea, UK, to determine possible changes in the instrument impulse response as a function of signal charge delivered in 1 ns. Precision NToF measurements at approximately 20 m require that we characterize changes in the impulse response moments to <40 ps for the first central moment and ∼2% rms for the square root of the second central moment with ∼500 ps value. Detailed results are presented for three different diode configurations.

  13. Using historical ecology to reassess the conservation status of coniferous forests in Central Europe.

    PubMed

    Szabó, Péter; Kuneš, Petr; Svobodová-Svitavská, Helena; Švarcová, Markéta Gabriela; Křížová, Lucie; Suchánková, Silvie; Müllerová, Jana; Hédl, Radim

    2017-02-01

    Forests cover approximately one-third of Central Europe. Oak (Quercus) and European beech (Fagus sylvatica) are considered the natural dominants at low and middle elevations, respectively. Many coniferous forests (especially of Picea abies) occur primarily at midelevations, but these are thought to have resulted from forestry plantations planted over the past 200 years. Nature conservation and forestry policy seek to promote broadleaved trees over conifers. However, there are discrepancies between conservation guidelines (included in Natura 2000) and historical and palaeoecological data with regard to the distribution of conifers. Our aim was to bring new evidence to the debate on the conservation of conifers versus broadleaved trees at midelevations in Central Europe. We created a vegetation and land-cover model based on pollen data for a highland area of 11,300 km 2 in the Czech Republic and assessed tree species composition in the forests before the onset of modern forestry based on 18th-century archival sources. Conifers dominated the study region throughout the entire Holocene (approximately 40-60% of the area). Broadleaved trees were present in a much smaller area than envisaged by current ideas of natural vegetation. Rather than casting doubt on the principles of Central European nature conservation in general, our results highlight the necessity of detailed regional investigations and the importance of historical data in challenging established notions on the natural distribution of tree species. © 2016 Society for Conservation Biology.

  14. Periodontal probing of an impacted tooth recovered through a surgical-orthodontic approach: a case report.

    PubMed

    Dinoi, Maria Teresa; Lacarbonara, Mariano; Dimartino, Salvatore; Monaco, Annalisa; Marzo, Giuseppe

    2014-01-27

    The aim of this work was to assess the periodontal support of a central upper incisor recovered through a surgical-orthodontic approach compared to the spontaneously erupted contralateral incisor. This case study describes an 8-year-old Caucasian female with an impacted upper right central incisor. Surgical-orthodontic treatment was performed to reset the impacted dental element in the arch. Periodontal probing was performed of all sites (mesio-buccal, central-buccal, disto-buccal, mesio-palatal, central-palatal and disto-palatal) of the recovered impacted tooth and the contralateral tooth. The results were compared to determine whether the treated element showed signs of periodontal injury. Most of the probing results on both her right and left incisors gave values of approximately 3mm, which were not considered pathological. Both dental elements had adequate and physiological osseous attachments.

  15. Triatoma dimidiata Infestation in Chagas Disease Endemic Regions of Guatemala: Comparison of Random and Targeted Cross-Sectional Surveys

    PubMed Central

    King, Raymond J.; Cordon-Rosales, Celia; Cox, Jonathan; Kitron, Uriel D.

    2011-01-01

    Background Guatemala is presently engaged in the Central America Initiative to interrupt Chagas disease transmission by reducing intradomiciliary prevalence of Triatoma dimidiata, using targeted cross-sectional surveys to direct control measures to villages exceeding the 5% control threshold. The use of targeted surveys to guide disease control programs has not been evaluated. Here, we compare the findings from the targeted surveys to concurrent random cross-sectional surveys in two primary foci of Chagas disease transmission in central and southeastern Guatemala. Methodology/Principal Findings Survey prevalences of T. dimidiata intradomiciliary infestation by village and region were compared. Univariate logistic regression was used to assess the use of risk factors to target surveys and to evaluate indicators associated with village level intradomiciliary prevalences >5% by survey and region. Multivariate logistic regression models were developed to assess the ability of random and targeted surveys to target villages with intradomiciliary prevalence exceeding the control threshold within each region. Regional prevalences did not vary by survey; however, village prevalences were significantly greater in random surveys in central (13.0% versus 8.7%) and southeastern (22.7% versus 6.9%) Guatemala. The number of significant risk factors detected did not vary by survey in central Guatemala but differed considerably in the southeast with a greater number of significant risk factors in the random survey (e.g. land surface temperature, relative humidity, cropland, grassland, tile flooring, and stick and mud and palm and straw walls). Differences in the direction of risk factor associations were observed between regions in both survey types. The overall discriminative capacity was significantly greater in the random surveys in central and southeastern Guatemala, with an area under the receiver-operator curve (AUC) of 0.84 in the random surveys and approximately 0.64 in the targeted surveys in both regions. Sensitivity did not differ between surveys, but the positive predictive value was significantly greater in the random surveys. Conclusions/Significance Surprisingly, targeted surveys were not more effective at determining T. dimidiata prevalence or at directing control to high risk villages in comparison to random surveys. We recommend that random surveys should be selected over targeted surveys whenever possible, particularly when the focus is on directing disease control and elimination and when risk factor association has not been evaluated for all regions under investigation. PMID:21532742

  16. Temporal resolution improvement using PICCS in MDCT cardiac imaging.

    PubMed

    Chen, Guang-Hong; Tang, Jie; Hsieh, Jiang

    2009-06-01

    The current paradigm for temporal resolution improvement is to add more source-detector units and/or increase the gantry rotation speed. The purpose of this article is to present an innovative alternative method to potentially improve temporal resolution by approximately a factor of 2 for all MDCT scanners without requiring hardware modification. The central enabling technology is a most recently developed image reconstruction method: Prior image constrained compressed sensing (PICCS). Using the method, cardiac CT images can be accurately reconstructed using the projection data acquired in an angular range of about 120 degrees, which is roughly 50% of the standard short-scan angular range (approximately 240 degrees for an MDCT scanner). As a result, the temporal resolution of MDCT cardiac imaging can be universally improved by approximately a factor of 2. In order to validate the proposed method, two in vivo animal experiments were conducted using a state-of-the-art 64-slice CT scanner (GE Healthcare, Waukesha, WI) at different gantry rotation times and different heart rates. One animal was scanned at heart rate of 83 beats per minute (bpm) using 400 ms gantry rotation time and the second animal was scanned at 94 bpm using 350 ms gantry rotation time, respectively. Cardiac coronary CT imaging can be successfully performed at high heart rates using a single-source MDCT scanner and projection data from a single heart beat with gantry rotation times of 400 and 350 ms. Using the proposed PICCS method, the temporal resolution of cardiac CT imaging can be effectively improved by approximately a factor of 2 without modifying any scanner hardware. This potentially provides a new method for single-source MDCT scanners to achieve reliable coronary CT imaging for patients at higher heart rates than the current heart rate limit of 70 bpm without using the well-known multisegment FBP reconstruction algorithm. This method also enables dual-source MDCT scanner to achieve higher temporal resolution without further hardware modifications.

  17. Elastic expansion of the lithosphere caused by groundwater withdrawal in south-central Arizona

    USGS Publications Warehouse

    Holzer, T.L.

    1979-01-01

    Relative crustal uplift observed from 1948-1949 to 1967 in the Lower Santa Cruz River Basin in south-central Arizona is attributed at least in part to elastic expansion of the lithosphere induced by the removal, and subsequent loss by evapo transpiration, of 4.35 ?? 1013 kg of groundwater from alluvium. The area of unloading is approximately 8070 km2. Uplift, relative to an apparently stable area west of the unloaded area, was observed in two areas near Casa Grande and Florence where crystalline bedrock is either close to the land surface or crops out through alluvium from which groundwater was withdrawn. The magnitudes of uplift were approximately 6.3 and 7.5 cm respectively. The observations are based on first-order leveling. The observations are significant at three standard deviations for random surveying errors, and are not believed to be affected by systematic errors. However, the 7.5-cm uplift observed at Florence may be from 1 to 2 cm in excess of the actual uplift because of the possibility of subsidence of a tie point due to groundwater pumping during the leveling in 1948-1949. Uplift is attributed to groundwater withdrawal on three bases. First, the observed uplift is consistent with a theoretical evaluation of elastic expansion based on linear elasticity theory. For the observed distribution of unloading and uplift and a Poisson's ratio of 0.25, a Young's modulus for the lithosphere of approximately 0.68 Mbar is implied. This value is comparable to values of the lithosphere reported elsewhere. Second, the magnitude of uplift compares favorably with the magnitude of elastic depression caused by the formation of Lake Mead, Arizona-Nevada, 430 km northwest of the study area, when allowance is made for the different magnitudes and areal distributions of surface (un)loading. And third, in the area near Casa Grande, a reversal in the sense of bedrock displacement form subsidence of tectonic origin to uplift approximately coincided with the beginning of large groundwater overdraft. The uplift from 1948 to 1967 near Casa Grande was preceded from 1905 to 1948 by 7-8 cm of tectonic subsidence; no precise data for the area near Florence are available before 1948. ?? 1979.

  18. FDTD simulation of EM wave propagation in 3-D media

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, T.; Tripp, A.C.

    1996-01-01

    A finite-difference, time-domain solution to Maxwell`s equations has been developed for simulating electromagnetic wave propagation in 3-D media. The algorithm allows arbitrary electrical conductivity and permittivity variations within a model. The staggered grid technique of Yee is used to sample the fields. A new optimized second-order difference scheme is designed to approximate the spatial derivatives. Like the conventional fourth-order difference scheme, the optimized second-order scheme needs four discrete values to calculate a single derivative. However, the optimized scheme is accurate over a wider wavenumber range. Compared to the fourth-order scheme, the optimized scheme imposes stricter limitations on the time stepmore » sizes but allows coarser grids. The net effect is that the optimized scheme is more efficient in terms of computation time and memory requirement than the fourth-order scheme. The temporal derivatives are approximated by second-order central differences throughout. The Liao transmitting boundary conditions are used to truncate an open problem. A reflection coefficient analysis shows that this transmitting boundary condition works very well. However, it is subject to instability. A method that can be easily implemented is proposed to stabilize the boundary condition. The finite-difference solution is compared to closed-form solutions for conducting and nonconducting whole spaces and to an integral-equation solution for a 3-D body in a homogeneous half-space. In all cases, the finite-difference solutions are in good agreement with the other solutions. Finally, the use of the algorithm is demonstrated with a 3-D model. Numerical results show that both the magnetic field response and electric field response can be useful for shallow-depth and small-scale investigations.« less

  19. Growth and yield models for central hardwoods

    Treesearch

    Martin E. Dale; Donald E. Hilt

    1989-01-01

    Over the last 20 years computers have become an efficient tool to estimate growth and yield. Computerized yield estimates vary from simple approximation or interpolation of traditional normal yield tables to highly sophisticated programs that simulate the growth and yield of each individual tree.

  20. Behavioural Indices of Central Auditory Processing

    DTIC Science & Technology

    2009-06-01

    materials were presented monaurally or binaurally over a headset at a comfortable listening level. All but the Gaps-in-Noise Test were presented twice...Milford, New Hampshire). Stimulus materials were pesented monaurally or binaurally at a comfortable listening level of approximately 50 decibels above

  1. 78 FR 65040 - Chicago Central & Pacific Railroad Company-Abandonment Exemption-in Linn County, Iowa

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... Abandonments to abandon an approximately 0.49-mile line of railroad extending between milepost 230.24 and... assessment (EA) on October 23, 2013. Interested persons may obtain a copy of the EA by writing to OEA (Room...

  2. Site characteristics and prey abundance at foraging sites used by Lesser Scaup (Aythya affinis) wintering in Florida

    USGS Publications Warehouse

    Herring, Garth; Collazo, Jaime

    2009-01-01

    We examined site characteristics and prey abundances where wintering Aythya affinis (Lesser Scaup; hereafter scaup) foraged within three regions of the Indian River Lagoon system in central Florida. We observed that scaup concentrated in the Indian and Banana rivers; however, density of prey items did not differ between foraging sites and random sites. We also found that site characteristics were similar between foraging and random sites. Differences in site characteristics between random points across all three regions did not explain the distribution of Foraging scaup (no scaup foraged in the Mosquito Lagoon); however, prey densities were approximately 3 times lower in the Mosquito Lagoon region. Our study suggests that current habitat conditions within the northern Indian River Lagoon system meet the overwintering requirements of scaup; however, prey densities in the Mosquito Lagoon may have been too low to be profitable for foraging scaup during the period of our study.

  3. Decay of Far-Flowfield in Trailing Vortices

    NASA Technical Reports Server (NTRS)

    Baldwin, B. S.; Chigier, N. A.; Sheaffer, Y. S.

    1973-01-01

    Methods for reduction of velocities in trailing vortices of large aircraft are of current interest for the purpose of shortening the waiting time between landings at central airports. We have made finite-difference calculations of the flow in turbulent wake vortices as an aid to interpretation of wind-tunnel and flight experiments directed toward that end. Finite-difference solutions are capable of adding flexibility to such investigations if they are based on an adequate model of turbulence. Interesting developments have been taking place in the knowledge of turbulence that may lead to a complete theory in the future. In the meantime, approximate methods that yield reasonable agreement with experiment are appropriate. The simplified turbulence model we have selected contains features that account for the major effects disclosed by more sophisticated models in which the parameters are not yet established. Several puzzles are thereby resolved that arose in previous theoretical investigations of wake vortices.

  4. Parallel gradualistic evolution of Ordovician trilobites.

    PubMed

    Sheldon, P R

    There are very few high-resolution studies of the fossil record from which to assess the relative frequency of gradualistic and punctuated evolution. Here I report some of the first detailed evidence of phyletic gradualism in benthic macroinvertebrates, based on a study of approximately 15,000 trilobites from central Wales. Over a period of about three million years, as many as eight lineages underwent a net increase in the number of pygidial ribs, a species-diagnostic character. The end members of most lineages have previously been assigned to different species and, in one case, to different genera. In view of intermediate morphologies and temporary trend reversals, however, practical taxonomic subdivision of each lineage proved impossible. The apparent success of earlier Linnean nomenclature (with its implications of discrete species) could easily have been misinterpreted as evidence of punctuation and stasis, and it is probable that detection of many other gradualistic patterns has been hindered by ready application of binominal taxonomy to fossils.

  5. Earth Observation

    NASA Image and Video Library

    2012-07-29

    ISS032-E-010482 (29 July 2012) --- Sutter Buttes in California are featured in this image photographed by an Expedition 32 crew member on the International Space Station. Sometimes called the ?smallest mountain range in the world?, the Sutter Buttes rise almost 610 meters above the surrounding flat agricultural fields of the Great Valley of central California. Scientists believe the Sutter Buttes are remnants of a volcano that was active approximately 1.6 ? 1.4 million years ago during the Pleistocene Epoch. The central core of the Buttes is characterized by lava domes?piles of viscous lava that erupted onto the surface, building higher with each successive layer. Today, these lava domes form the high central hills of the Buttes; shadows cast by the hills are visible at center. Surrounding the central core is an apron of fragmental material created by occasional eruptions of the lava domes ? this apron extends roughly 18 kilometers east-west and 16 kilometers north-south. The volcanic material was transported outwards from the central core during eruptions by hot gasses (pyroclastic flows) or by cooler water-driven flows (lahars). Later stream erosion of the debris apron is evident from the radial drainage pattern surrounding the central core. A third geomorphic region of valleys known as the ?moat? is present between the core and the debris apron, and was formed from erosion of older, exposed sedimentary rocks that underlie the volcanic rocks. The Sutter Buttes present a striking visual contrast with the surrounding green agricultural fields?here mostly rice, with some sunflower, winter wheat, tomato, and almonds?of the Great Valley. Urban areas such as Yuba City, CA (located 18 kilometers to the southeast) appear as light to dark gray stippled regions. Sacramento, CA (not shown) is located approximately 80 kilometers to the south-southeast. The image appears slightly distorted (oblique) due to the viewing angle from the space station.

  6. Infrared photometry of the black hole candidate Sagittarius A*

    NASA Technical Reports Server (NTRS)

    Close, Laird M.; Mccarthy, Donald W. JR.; Melia, Fulvio

    1995-01-01

    An infrared source has been imaged within 0.2 +/- 0.3 arcseconds of the unique Galactic center radio source Sgr A* High angular resolution (averaged value of the Full Width at Half Maximum (FWHM) approximately 0.55 arcseconds) was achieved by rapid (approximately 50 Hz) real-time images motion compensation. The source's near-infrared magnitudes (K = 12.1 +/- 0.3, H = 13.7 +/- 0.3, and J = 16.6 +/- 0.4) are consistent with a hot object reddened by the local extinction A(sub v) approximately 27). At the 3 sigma level of confidence, a time series of 80 images limits the source variability to less than 50% on timescales from 3 to 30 minutes. The photometry is consistent with the emission from a simple accretion disk model for a approximately 1 x 10(exp 6) solar mass black hole. However, the fluxes are also consistent with a hot luminous (L approximately 10(exp 3.5) to 10(exp 4-6) solar luminosity) central cluster star positionally coincident with Sgr A*.

  7. Alluvial diamond resource potential and production capacity assessment of the Central African Republic

    USGS Publications Warehouse

    Chirico, Peter G.; Barthelemy, Francis; Ngbokoto, Francois A.

    2010-01-01

    In May of 2000, a meeting was convened in Kimberley, South Africa, and attended by representatives of the diamond industry and leaders of African governments to develop a certification process intended to assure that rough, exported diamonds were free of conflict concerns. This meeting was supported later in 2000 by the United Nations in a resolution adopted by the General Assembly. By 2002, the Kimberly Process Certification Scheme (KPCS) was ratified and signed by diamond-producing and diamond-importing countries. Over 70 countries were included as members of the KPCS at the end of 2007. To prevent trade in "conflict diamonds" while protecting legitimate trade, the KPCS requires that each country set up an internal system of controls to prevent conflict diamonds from entering any imported or exported shipments of rough diamonds. Every diamond or diamond shipment must be accompanied by a Kimberley Process (KP) certificate and be contained in tamper-proof packaging. The objective of this study was (1) to assess the naturally occurring endowment of diamonds in the Central African Republic (potential resources) based on geological evidence, previous studies, and recent field data and (2) to assess the diamond-production capacity and measure the intensity of mining activity. Several possible methods can be used to estimate the potential diamond resource. However, because there is generally a lack of sufficient and consistent data recording all diamond mining in the Central African Republic and because time to conduct fieldwork and accessibility to the diamond mining areas are limited, two different methodologies were used: the volume and grade approach and the content per kilometer approach. Estimates are that approximately 39,000,000 carats of alluvial diamonds remain in the eastern and western zones of the CAR combined. This amount is roughly twice the total amount of diamonds reportedly exported from the Central African Republic since 1931. Production capacity is calculated to be 840,000 carats per year, a number that is nearly twice the 450,000 carats per year reported annually by the Central African Republic. The difference in the two numbers reflects the lack of sufficient data on diamond resource grades, worker productivity, and the number and locations of sites being worked.

  8. Central-place foraging and ecological effects of an invasive predator across multiple habitats.

    PubMed

    Benkwitt, Cassandra E

    2016-10-01

    Cross-habitat foraging movements of predators can have widespread implications for predator and prey populations, community structure, nutrient transfer, and ecosystem function. Although central-place foraging models and other aspects of optimal foraging theory focus on individual predator behavior, they also provide useful frameworks for understanding the effects of predators on prey populations across multiple habitats. However, few studies have examined both the foraging behavior and ecological effects of nonnative predators across multiple habitats, and none has tested whether nonnative predators deplete prey in a manner predicted by these foraging models. I conducted behavioral observations of invasive lionfish (Pterois volitans) to determine whether they exhibit foraging movements similar to other central-place consumers. Then, I used a manipulative field experiment to test whether their effects on prey populations are consistent with three qualitative predictions from optimal foraging models. Specifically, I predicted that the effects of invasive lionfish on native prey will (1) occur at central sites first and then in surrounding habitats, (2) decrease with increasing distance away from their shelter site, and (3) extend to greater distances when prey patches are spaced closer together. Approximately 40% of lionfish exhibited short-term crepuscular foraging movements into surrounding habitats from the coral patch reefs where they shelter during daylight hours. Over the course of 7 weeks, lionfish depleted native fish populations on the coral patch reefs where they reside, and subsequently on small structures in the surrounding habitat. However, their effects did not decrease with increasing distance from the central shelter site and the influence of patch spacing was opposite the prediction. Instead, lionfish always had the greatest effects in areas with the highest prey densities. The differences between the predicted and observed effects of lionfish foraging are likely due to different constraints faced by invasive predators compared to native predators, namely that lionfish do not face increased predation risk with increased movement away from shelter sites. By foraging at greater distances from patch reefs than native predators, lionfish eliminated a spatial refuge from predation used by juveniles of many commercially and ecologically important reef fishes. © 2016 by the Ecological Society of America.

  9. The Anisotropic Structure of South China Sea: Using OBS Data to Constrain Mantle Flow

    NASA Astrophysics Data System (ADS)

    Li, L.; Xue, M.; Yang, T.; Liu, C.; Hua, Q.; Xia, S.; Huang, H.; Le, B. M.; Huo, D.; Pan, M.

    2015-12-01

    The dynamic mechanism of the formation of South China Sea (SCS) has been debated for decades. The anisotropic structure can provide useful insight into the complex evolution of SCS by indicating its mantle flow direction and strength. In this study, we employ shear wave splitting methods on two half-year seismic data collected from 10 and 6 passive source Ocean Bottom Seismometers (OBS) respectively. These OBSs were deployed along both sides of the extinct ridge in the central basin of SCS by Tongji University in 2012 and 2013 respectively, which were then successfully recovered in 2013 and 2015 respectively. Through processing and inspecting the global and regional earthquakes (with local events being processing) of the 2012 dataset, measurements are made for 2 global events and 24 regional events at 5 OBSs using the tangential energy minimization, the smallest eigenvalue minimization, as well as the correlation methods. We also implement cluster analysis on the splitting results obtained for different time windows as well as filtered at different frequency bands. For teleseismic core phases like SKS and PKS, we find the fast polarization direction beneath the central basin is approximately NE-SW, nearly parallel to the extinct ridge in the central basin of SCS. Whereas for regional events, the splitting analysis on S, PS and ScS phases shows much more complicated fast directions as the ray path varies for different phases. The fast directions observed can be divided into three groups: (1) for the events from the Eurasia plate, a gradual rotation of the fast polarization direction from NNE-SSW to NEE-SWW along the path from the inner Eurasia plate to the central SCS is observed, implying the mantle flow is controlled by the India-Eurasia collision; (2) for the events located at the junction of Pacific plate and Philippine plate, the dominant fast direction is NW-SE, almost perpendicular to Ryukyu Trench as well as sub-parallel to the absolute direction of Philippine plate; (3) for the events occurred in the SE direction near the Philippine Fault zone, the observed NE-SW fast direction is sub-parallel to the subduction direction of the Philippine plate.

  10. The sub-chronic toxicity of regular White Spirit in rats.

    PubMed

    Carrillo, Juan-Carlos; Adenuga, M David; Mckee, Richard H

    2014-10-01

    Hydrocarbon solvents are mostly complex substances (UVCB) with carbon numbers in the range of approximately C5-C20. One of the most common types is a C9-C14 aliphatic solvent containing approximately 20% aromatics and commonly known as White Spirit in Europe and mineral spirits in the US. In previous repeated inhalation toxicity studies, White Spirit was reported to cause minimal systemic effects in most animal species with few effects other than male rat-specific kidney changes at levels up to approximately 2000mg/m(3). In the present study male and female rats were exposed to White Spirit vapors, 6h/day, 5days/week for 13weeks at levels of approximately 2000, 4000, or 8000mg/m(3) to assess the potential for effects at higher exposure levels. All of the rats survived the treatment period. In life observations were largely restricted to acute central nervous system (CNS) effects in the high exposure group. Terminal body weights of high exposure groups animals were significantly below control values. Statistically significant differences in the clinical and hematological observations were small and within normal physiological limits. Weights of some organs including liver, spleen and kidneys were elevated, but microscopic examination indicated that the only pathological effects were changes in the kidneys of the male rats, consistent with an α2u-globulin-mediated process, which is gender and species-specific and not relevant to humans. The overall no observed adverse effect level (NOAEC) was 4000mg/m(3). Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Determining the best forecasting method to estimate unitary charges price indexes of PFI data in central region Peninsular Malaysia

    NASA Astrophysics Data System (ADS)

    Ahmad Kamaruddin, Saadi Bin; Md Ghani, Nor Azura; Mohamed Ramli, Norazan

    2013-04-01

    The concept of Private Financial Initiative (PFI) has been implemented by many developed countries as an innovative way for the governments to improve future public service delivery and infrastructure procurement. However, the idea is just about to germinate in Malaysia and its success is still vague. The major phase that needs to be given main attention in this agenda is value for money whereby optimum efficiency and effectiveness of each expense is attained. Therefore, at the early stage of this study, estimating unitary charges or materials price indexes in each region in Malaysia was the key objective. This particular study aims to discover the best forecasting method to estimate unitary charges price indexes in construction industry by different regions in the central region of Peninsular Malaysia (Selangor, Federal Territory of Kuala Lumpur, Negeri Sembilan, and Melaka). The unitary charges indexes data used were from year 2002 to 2011 monthly data of different states in the central region Peninsular Malaysia, comprising price indexes of aggregate, sand, steel reinforcement, ready mix concrete, bricks and partition, roof material, floor and wall finishes, ceiling, plumbing materials, sanitary fittings, paint, glass, steel and metal sections, timber and plywood. At the end of the study, it was found that Backpropagation Neural Network with linear transfer function produced the most accurate and reliable results for estimating unitary charges price indexes in every states in central region Peninsular Malaysia based on the Root Mean Squared Errors, where the values for both estimation and evaluation sets were approximately zero and highly significant at p < 0.01. Therefore, artificial neural network is sufficient to forecast construction materials price indexes in Malaysia. The estimated price indexes of construction materials will contribute significantly to the value for money of PFI as well as towards Malaysian economical growth.

  12. Effect of hole size on fluid dynamics of a posterior-chamber phakic intraocular lens with a central perforation by using computational fluid dynamics.

    PubMed

    Kawamorita, Takushi; Shimizu, Kimiya; Shoji, Nobuyuki

    2016-04-01

    A modified implantable collamer lens (ICL) with a central hole with a diameter of 0.36 mm, referred to as a hole-ICL, was created to improve aqueous humour circulation. The aim of this study is to investigate the ideal hole size in a hole-ICL from the standpoint of the fluid dynamic characteristics of the aqueous humour using computational fluid dynamics. Fluid dynamics simulation using an ICL was performed with thermal-hydraulic analysis software FloEFD V 12.2 (Mentor Graphics Corp.). In the simulation, three-dimensional eye models based on a modified Liou-Brennan model eye with a conventional ICL (Model ICM, Staar Surgical) and a hole-ICL were used. The hole-ICL was -9.0 dioptres (D) and 12.0 mm in length, with an optic zone of 5.5 mm. The vaulting was 0.50 mm. The quantity of aqueous humour produced by the ciliary body was set at 2.80 μL/min. Flow distribution between the anterior surface of the crystalline lens and the posterior surface of the ICL was calculated, and trajectory analysis was performed. With an increase in the central hole size, the velocity of the aqueous humour increased, with the peak velocity occurring at a diameter of approximately 0.4 mm. Once the diameter had increased above 0.4 mm, the velocity then decreased. The velocity difference between the cases of a central hole size of 0.1 mm and 0.2 mm was significant. The desirable central hole size was 0.2 mm or larger in terms of flow dynamics. The current model, based on a central hole size of 0.36 mm, was close to ideal. The optimisation of the hole size should be performed based on results from a long-term clinical study so as to analyse the incidence rate of secondary cataract and optical performance.

  13. Adiposity and Blood Pressure in 110 000 Mexican Adults

    PubMed Central

    Gnatiuc, Louisa; Halsey, Jim; Herrington, William G.; López-Cervantes, Malaquías; Lewington, Sarah; Collins, Rory; Tapia-Conyer, Roberto; Peto, Richard; Kuri-Morales, Pablo

    2017-01-01

    Previous studies have reached differing conclusions about the importance of general versus central markers of adiposity to blood pressure, leading to suggestions that population-specific adiposity thresholds may be needed. We examined the relevance of adiposity to blood pressure among 111 911 men and women who, when recruited into the Mexico City Prospective Study, were aged 35 to 89 years, had no chronic disease, and were not taking antihypertensives. Linear regression was used to estimate the effects on systolic and diastolic blood pressure of 2 markers of general adiposity (body mass index and height-adjusted weight) and 4 markers of central adiposity (waist circumference, hip circumference, waist:hip ratio, and waist:height ratio), adjusted for relevant confounders. Mean (SD) adiposity levels were: body mass index (28.7±4.5 kg/m2), height-adjusted weight (70.2±11.2 kg), waist circumference (93.3±10.6 cm), hip circumference (104.0±9.0 cm), waist:hip ratio (0.90±0.06), and waist:height ratio (0.60±0.07). Associations with blood pressure were linear with no threshold levels below which lower general or central adiposity was not associated with lower blood pressure. On average, each 1 SD higher measured adiposity marker was associated with a 3 mm Hg higher systolic blood pressure and 2 mm Hg higher diastolic blood pressure (SEs <0.1 mm Hg), but for the waist:hip ratio, associations were only approximately half as strong. General adiposity associations were independent of central adiposity, but central adiposity associations were substantially reduced by adjustment for general adiposity. Findings were similar for men and women. In Mexican adults, often overweight or obese, markers of general adiposity were stronger independent predictors of blood pressure than measured markers of central adiposity, with no threshold effects. PMID:28223471

  14. AEGIS-X: Deep Chandra Imaging of the Central Groth Strip

    NASA Astrophysics Data System (ADS)

    Nandra, K.; Laird, E. S.; Aird, J. A.; Salvato, M.; Georgakakis, A.; Barro, G.; Perez-Gonzalez, P. G.; Barmby, P.; Chary, R.-R.; Coil, A.; Cooper, M. C.; Davis, M.; Dickinson, M.; Faber, S. M.; Fazio, G. G.; Guhathakurta, P.; Gwyn, S.; Hsu, L.-T.; Huang, J.-S.; Ivison, R. J.; Koo, D. C.; Newman, J. A.; Rangel, C.; Yamada, T.; Willmer, C.

    2015-09-01

    We present the results of deep Chandra imaging of the central region of the Extended Groth Strip, the AEGIS-X Deep (AEGIS-XD) survey. When combined with previous Chandra observations of a wider area of the strip, AEGIS-X Wide (AEGIS-XW), these provide data to a nominal exposure depth of 800 ks in the three central ACIS-I fields, a region of approximately 0.29 deg2. This is currently the third deepest X-ray survey in existence; a factor ∼ 2-3 shallower than the Chandra Deep Fields (CDFs), but over an area ∼3 times greater than each CDF. We present a catalog of 937 point sources detected in the deep Chandra observations, along with identifications of our X-ray sources from deep ground-based, Spitzer, GALEX, and Hubble Space Telescope imaging. Using a likelihood ratio analysis, we associate multiband counterparts for 929/937 of our X-ray sources, with an estimated 95% reliability, making the identification completeness approximately 94% in a statistical sense. Reliable spectroscopic redshifts for 353 of our X-ray sources are available predominantly from Keck (DEEP2/3) and MMT Hectospec, so the current spectroscopic completeness is ∼38%. For the remainder of the X-ray sources, we compute photometric redshifts based on multiband photometry in up to 35 bands from the UV to mid-IR. Particular attention is given to the fact that the vast majority the X-ray sources are active galactic nuclei and require hybrid templates. Our photometric redshifts have mean accuracy of σ =0.04 and an outlier fraction of approximately 5%, reaching σ =0.03 with less than 4% outliers in the area covered by CANDELS . The X-ray, multiwavelength photometry, and redshift catalogs are made publicly available.

  15. High rotational CO lines in post-AGB stars and PNe

    NASA Technical Reports Server (NTRS)

    Justtanont, K.; Tielens, Alexander G. G. M.; Skinner, C. J.; Haas, Michael R.

    1995-01-01

    A significant fraction of a star's initial mass is lost while it is on the Asymptotic Giant Branch (AGB). Mass loss rates range from 10(exp -7) solar mass/yr for early AGB stars to a few 10(exp -4) solar mass/yr for stars at the tip of the AGB. Dust grains condense from the outflow as the gas expands and form a dust shell around the central star. A superwind (approximately 10(exp -4) to 10(exp -3) solar mass/yr) is thought to terminate the AGB phase. In the post-AGB phase, the star evolves to a higher effective temperature, the mass loss decreases (approximately 10(exp -8) solar mass/yr), but the wind velocity increases (approximately 1000 km/s). During this evolution, dust and gas are exposed to an increasingly harsher radiation field and when T(sub eff) reaches about 30,000 K, the nebula is ionized and becomes a planetary nebula (PN). Photons from the central star can create a photodissociation region (PDR) in the expanding superwind. Gas can be heated through the photoelectric effect working on small grains and polycyclic aromatic hydrocarbons (PAH's). This gas can cool via the atomic fine structure lines of O I (63 microns and 145 microns) and C II (158 microns), as well as the rotational lines of CO. In the post-AGB phase, the fast wind from the central star will interact with the material ejected during the AGB phase. The shock caused by this interaction will dissociate and heat the gas. This warm gas will cool through atomic fine structure lines of O I and the rotational lines of (newly formed) CO.

  16. Structural control on arc volcanism: The Caviahue Copahue complex, Central to Patagonian Andes transition (38°S)

    NASA Astrophysics Data System (ADS)

    Melnick, Daniel; Folguera, Andrés; Ramos, Victor A.

    2006-11-01

    This paper describes the volcanostratigraphy, structure, and tectonic implications of an arc volcanic complex in an oblique subduction setting: the Caviahue caldera Copahue volcano (CAC) of the Andean margin. The CAC is located in a first-order morphotectonic transitional zone, between the low and narrow Patagonian and the high and broad Central Andes. The evolution of the CAC started at approximately 4-3 Ma with the opening of the 20 × 15 km Caviahue pull-apart caldera; Las Mellizas volcano formed inside the caldera and collapsed at approximately 2.6 Ma; and the Copahue volcano evolved in three stages: (1) 1.2-0.7 Ma formed the approximately 1 km thick andesitic edifice, (2) 0.7-0.01 Ma erupted andesitic-dacitic subglacial pillow lavas, and (3) 0.01-0 Ma erupted basaltic-andesites and pyroclastic flows from fissures, aligned cones, and summit craters. Magma ascent has occurred along planes perpendicular to the least principal horizontal stress, whereas hydrothermal activity and hot springs also occur along parallel planes. At a regional scale, Quaternary volcanism concentrates along the NE-trending, 90 km long Callaqui-Copahue-Mandolegüe lineament, the longest of the southern volcanic zone, which is here interpreted as an inherited crustal-scale transfer zone from a Miocene rift basin. At a local scale within the CAC, effusions are controlled by local structures that formed at the intersection of regional fault systems. The Central to Patagonian Andes transition occurs at the Callaqui-Copahue-Mandolegüe lineament, which decouples active deformation from the intra-arc strike-slip Liquiñe-Ofqui fault zone to the south and the backarc Copahue-Antiñir thrust system.

  17. Diffraction and imaging study of imperfections of crystallized lysozyme with coherent X-rays

    NASA Technical Reports Server (NTRS)

    Hu, Z. W.; Chu, Y. S.; Lai, B.; Thomas, B. R.; Chernov, A. A.

    2004-01-01

    Phase-contrast X-ray diffraction imaging and high-angular-resolution diffraction combined with phase-contrast radiographic imaging were employed to characterize defects and perfection of a uniformly grown tetragonal lysozyme crystal in the symmetric Laue case. The full-width at half-maximum (FWHM) of a 4 4 0 rocking curve measured from the original crystal was approximately 16.7 arcsec and imperfections including line defects, inclusions and other microdefects were observed in the diffraction images of the crystal. The observed line defects carry distinct dislocation features running approximately along the <1 1 0> growth front and have been found to originate mostly in a central growth area and occasionally in outer growth regions. Inclusions of impurities or formations of foreign particles in the central growth region are resolved in the images with high sensitivity to defects. Slow dehydration led to the broadening of a fairly symmetric 4 4 0 rocking curve by a factor of approximately 2.6, which was primarily attributed to the dehydration-induced microscopic effects that are clearly shown in X-ray diffraction images. The details of the observed defects and the significant change in the revealed microstructures with drying provide insight into the nature of imperfections, nucleation and growth, and the properties of protein crystals.

  18. User's manual for three dimensional FDTD version D code for scattering from frequency-dependent dielectric and magnetic materials

    NASA Technical Reports Server (NTRS)

    Beggs, John H.; Luebbers, Raymond J.; Kunz, Karl S.

    1992-01-01

    The Penn State Finite Difference Time Domain Electromagnetic Scattering Code version D is a 3-D numerical electromagnetic scattering code based upon the finite difference time domain technique (FDTD). The manual provides a description of the code and corresponding results for several scattering problems. The manual is organized into 14 sections: introduction; description of the FDTD method; operation; resource requirements; version D code capabilities; a brief description of the default scattering geometry; a brief description of each subroutine; a description of the include file; a section briefly discussing Radar Cross Section computations; a section discussing some scattering results; a sample problem setup section; a new problem checklist; references and figure titles. The FDTD technique models transient electromagnetic scattering and interactions with objects of arbitrary shape and/or material composition. In the FDTD method, Maxwell's curl equations are discretized in time-space and all derivatives (temporal and spatial) are approximated by central differences.

  19. Spectroscopy -- An introduction and overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Isgur, N.

    1999-02-01

    The study of baryons can provide one with critical insights into the nature of QCD in the confinement domain. The key to progress in this field is the identification of its important degrees of freedom. The author explains why he believes that the adiabatic approximation is central to understanding the absence of gluonic excitations at low energies, and describe an extension of this approximation which can help one to understand the resiliency of the valence quark model to meson loop corrections. He closes with a survey of issues that he hopes to see resolved before Baryon 2001.

  20. Optimum Distribution of Metal Particles in the Solid-Propellant Charge in the Approximation of a One-Dimensional Flow Field in a Cylindrical Channel

    NASA Astrophysics Data System (ADS)

    Min'kov, L. L.; Shrager, É. R.

    2015-03-01

    A study has been made of ways of optimum distribution of particles of dispersed metal in the solid-propellant charge with a cylindrical central channel, which is firmly fastened to the case. The efficiency of combustion of this metal has been analyzed. Consideration has been given to the influence of the dynamic nonequilibrium of two-phase flow on the optimum distribution of metal particles in the indicated charge in the approximation of one-dimensionality of the flow field.

  1. Thermal Conductance and High-Frequency Properties of Cryogenic Normal or Superconducting Semi-rigid Coaxial Cables in the Temperature Range of 1-8 K

    NASA Astrophysics Data System (ADS)

    Kushino, A.; Kasai, S.; Ukibe, M.; Ohkubo, M.

    2018-04-01

    In this study, the characteristics of thin semi-rigid cables composed of different conductors and with outer diameters ranging from 0.86 to 1.19 mm were investigated at low temperatures. The thermal conductance was measured between approximately 1 and 8 K, and the frequency dependence of the attenuation in the cables was obtained at 3 K. The electrical conductors used in the cables were alloys: beryllium copper, brass, stainless steel (SUS304), phosphor bronze, cupronickel (CuNi), and niobium-titanium (NbTi). The thermal conductance of a commercial miniature coaxial cable with braided wires forming the outer electrical conductor was also examined for reference. The measured thermal conductance was compared to published data and that generated from material libraries and databases. Among the measured cables using normal metals, the semi-rigid cable composed of SUS304 conductors and a polytetrafluoroethylene insulator showed the lowest thermal conductance. The transmission performance of the semi-rigid cables using SUS304 or CuNi was improved by plating the central conductors with a silver coating of approximately 3 μm thickness, and their thermal conductance with the plating increased by approximately one order of magnitude. The superconducting NbTi semi-rigid cable exhibited the lowest thermal conductance of all the cables considered in the present study along with very small attenuation up to above 5 GHz.

  2. A dynamical model for the formation of gas rings and episodic starbursts near galactic centres

    NASA Astrophysics Data System (ADS)

    Krumholz, Mark R.; Kruijssen, J. M. Diederik

    2015-10-01

    We develop a simple dynamical model for the evolution of gas in the centres of barred spiral galaxies, using the Milky Way's Central Molecular Zone (CMZ, i.e. the central few hundred pc) as a case study. We show that, in the presence of a galactic bar, gas in a disc in the central regions of a galaxy will be driven inwards by angular momentum transport induced by acoustic instabilities within the bar's inner Lindblad resonance. This transport process drives turbulence within the gas that temporarily keeps it strongly gravitationally stable and prevents the onset of rapid star formation. However, at some point the rotation curve must transition from approximately flat to approximately solid body, and the resulting reduction in shear reduces the transport rates and causes gas to build up, eventually producing a gravitationally unstable region that is subject to rapid and violent star formation. For the observed rotation curve of the Milky Way, the accumulation happens ˜100 pc from the centre of the Galaxy, in good agreement with the observed location of gas clouds and young star clusters in the CMZ. The characteristic time-scale for gas accumulation and star formation is of the order of 10-20 Myr. We argue that similar phenomena should be ubiquitous in other barred spiral galaxies.

  3. UIT ultraviolet imaging of 30 Doradus

    NASA Technical Reports Server (NTRS)

    Hintzen, P.; Cheng, K.-P.; Michalitsianos, A.; Bohlin, R.; O'Connell, R.; Cornett, R.; Roberts, M.; Smith, A.; Smith, E.; Stecher, T.

    1992-01-01

    During the Astro-1 mission, near- and far-UV images of the 30 Doradus region were obtained using the Ultraviolet Imaging Telescope (UIT). These wide-field, 40 min in diameter, high spatial resolution, 2-3 sec, UIT UV images reveal a rich field of luminous UV-bright stars, clusters, and associations. There are 181 stars brighter than m(sub 2558A) = 16.5 and 197 stars brighter than m(sub 1615A) = 16.4 within 3 min diameter of the 30 Doradus central cluster. We have derived UV fluxes emitted from the 30 Doradus central cluster and from its UV bright core, R136. The region within 5 sec of R136 produces approximately 14% of the far-UV flux (lambda = 1892 A) and approximately 16% of the near-UV flux (lambda = 2558 A) emitted from the 3 min diameter central cluster. The derived UV luminosity of R136 at 1892 A is only 7.8 times that of the nearby O6-7 Iaf star, R139, and the m(sub 1892) - m(sub v) colors of R136 are similar to other O or Wolf-Rayet stars in the same region. These UIT data, combined with other published observations at longer wavelengths, indicate that there is no observational evidence for a supermassive star in R136.

  4. UIT ultraviolet imaging of 30 Doradus

    NASA Astrophysics Data System (ADS)

    Hintzen, P.; Cheng, K.-P.; Michalitsianos, A.; Bohlin, R.; O'Connell, R.; Cornett, R.; Roberts, M.; Smith, A.; Smith, E.; Stecher, T.

    During the Astro-1 mission, near- and far-UV images of the 30 Doradus region were obtained using the Ultraviolet Imaging Telescope (UIT). These wide-field, 40 min in diameter, high spatial resolution, 2-3 sec, UIT UV images reveal a rich field of luminous UV-bright stars, clusters, and associations. There are 181 stars brighter than m2558A = 16.5 and 197 stars brighter than m1615A = 16.4 within 3 min diameter of the 30 Doradus central cluster. We have derived UV fluxes emitted from the 30 Doradus central cluster and from its UV bright core, R136. The region within 5 sec of R136 produces approximately 14% of the far-UV flux (lambda = 1892 A) and approximately 16% of the near-UV flux (lambda = 2558 A) emitted from the 3 min diameter central cluster. The derived UV luminosity of R136 at 1892 A is only 7.8 times that of the nearby O6-7 Iaf star, R139, and the m1892 - mv colors of R136 are similar to other O or Wolf-Rayet stars in the same region. These UIT data, combined with other published observations at longer wavelengths, indicate that there is no observational evidence for a supermassive star in R136.

  5. Pre-Hispanic agricultural decline prior to the Spanish Conquest in southern Central America

    NASA Astrophysics Data System (ADS)

    Taylor, Zachary P.; Horn, Sally P.; Finkelstein, David B.

    2013-08-01

    Archeological and paleoenvironmental records from southern Central America attribute population collapse to the Spanish Conquest about 500 years ago. Paleoclimate records from the circum-Caribbean have shown evidence of severe, regional droughts that contributed to the collapse of the Mayan Civilization, but there are few records of these droughts in southern Central America and no records of their effects on prehistoric populations in the region. Here we present a high-resolution lake sediment record of prehistoric agricultural activities using bulk sediment stable carbon isotopes from Laguna Zoncho, Costa Rica. We find isotopic evidence that agriculture was nearly absent from the watershed approximately 220 years prior to the Spanish arrival in Costa Rica and identify two distinct periods of agricultural decline, 1150-970 and 860-640 cal yr BP, which correspond to severe droughts in central Mexico. We attribute decreases in agriculture to a weakened Central American monsoon, which would have shortened the growing season at Laguna Zoncho, reduced crop yields, and negatively affected prehistoric populations.

  6. Norepinephrine transporter blocker atomoxetine increases salivary alpha amylase.

    PubMed

    Warren, Christopher M; van den Brink, Ruud L; Nieuwenhuis, Sander; Bosch, Jos A

    2017-04-01

    It has been suggested that central norepinephrine (NE) activity may be inferred from increases in salivary alpha-amylase (SAA), but data in favor of this proposition are limited. We administered 40mg of atomoxetine, a selective NE transporter blocker that increases central NE levels, to 24 healthy adult participants in a double-blind, placebo-controlled cross-over design. Atomoxetine administration significantly increased SAA secretion and concentrations at 75-180min after treatment (more than doubling baseline levels). Consistent with evidence that elevation in central NE is a co-determinant of hypothalamic-pituitary-adrenal axis activity, salivary cortisol also approximately doubled at the same time points. Moreover, changes in salivary cortisol positively correlated with SAA (0.44

  7. Computation and visualization of geometric partial differential equations

    NASA Astrophysics Data System (ADS)

    Tiee, Christopher L.

    The chief goal of this work is to explore a modern framework for the study and approximation of partial differential equations, recast common partial differential equations into this framework, and prove theorems about such equations and their approximations. A central motivation is to recognize and respect the essential geometric nature of such problems, and take it into consideration when approximating. The hope is that this process will lead to the discovery of more refined algorithms and processes and apply them to new problems. In the first part, we introduce our quantities of interest and reformulate traditional boundary value problems in the modern framework. We see how Hilbert complexes capture and abstract the most important properties of such boundary value problems, leading to generalizations of important classical results such as the Hodge decomposition theorem. They also provide the proper setting for numerical approximations. We also provide an abstract framework for evolution problems in these spaces: Bochner spaces. We next turn to approximation. We build layers of abstraction, progressing from functions, to differential forms, and finally, to Hilbert complexes. We explore finite element exterior calculus (FEEC), which allows us to approximate solutions involving differential forms, and analyze the approximation error. In the second part, we prove our central results. We first prove an extension of current error estimates for the elliptic problem in Hilbert complexes. This extension handles solutions with nonzero harmonic part. Next, we consider evolution problems in Hilbert complexes and prove abstract error estimates. We apply these estimates to the problem for Riemannian hypersurfaces in R. {n+1},generalizing current results for open subsets of R. {n}. Finally, we applysome of the concepts to a nonlinear problem, the Ricci flow on surfaces, and use tools from nonlinear analysis to help develop and analyze the equations. In the appendices, we detail some additional motivation and a source for further examples: canonical geometries that are realized as steady-state solutions to parabolic equations similar to that of Ricci flow. An eventual goal is to compute such solutions using the methods of the previous chapters.

  8. The 8 micron band of silicon monoxide in the expanding cloud around VY Canis Majoris

    NASA Technical Reports Server (NTRS)

    Geballe, T. R.; Lacy, J. H.; Beck, S. C.

    1979-01-01

    Observations of vibration-rotation transitions of silicon monoxide in VY CMa show that the lines originate in accelerating, expanding, and cool (about 600 K) layers of a circumstellar cloud at a distance of approximately 0.15 arcsec from the central star. The central stellar velocity, as estimated from observed SiO P Cygni line profiles, is somewhat redshifted from the midpoint of the maser emission features. Most of the silicon is probably in the form of dust grains. The isotopic ratios of silicon are nearly terrestrial.

  9. Interplay of soft and perturbative correlations in multiparton interactions at central rapidities

    DOE PAGES

    Blok, B.; Strikman, M.

    2017-06-22

    We study the role of soft/nonperturbative correlations in the multi parton interactions in the central kinematics relevant for double parton scattering (DPS) and underlying event (UE) measurements at ATLAS and CMS. We show that the effect of soft correlations is negligible for DPS regime (typical transverse momenta larger than 10–20 GeV), but may be important for UE (several GeV scale). The characteristic scale where soft correlations become important increases with decrease of x (energy increase) leading to approximately constant σ eff at small x.

  10. Flood of June 17, 1990, in the Clear Creek Basin, east-central Iowa

    USGS Publications Warehouse

    Barnes, K.K.; Eash, D.A.

    1994-01-01

    A water-surface-elevation profile for the flood of June 17, 1990, in the Clear Creek Basin, east-central Iowa, is given in this report. The maximum flood-peak discharge of 10,200 cubic feet per second for the streamflow-gaging station on Clear Creek near Coralville, Iowa (station number 05454300), occurred on June 17, 1990. This discharge was approximately equal to the 80-year recurrence-interval discharge. A flood history describes rainfall conditions for floods that occurred during 1982, 1990, and 1993.

  11. Interplay of soft and perturbative correlations in multiparton interactions at central rapidities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blok, B.; Strikman, M.

    We study the role of soft/nonperturbative correlations in the multi parton interactions in the central kinematics relevant for double parton scattering (DPS) and underlying event (UE) measurements at ATLAS and CMS. We show that the effect of soft correlations is negligible for DPS regime (typical transverse momenta larger than 10–20 GeV), but may be important for UE (several GeV scale). The characteristic scale where soft correlations become important increases with decrease of x (energy increase) leading to approximately constant σ eff at small x.

  12. Flood of August 31-September 1, 1978, in Crosswicks Creek basin and vicinity, central New Jersey

    USGS Publications Warehouse

    Vickers, Arthur A.

    1980-01-01

    A thunderstorm during the evening of August 31, 1978, caused flooding in a small area of south central New Jersey. Maximum peaks of record occurred on the upper Crosswicks Creek basin in the vicinity of Fort Dix, Wrightstown, and New Egypt. At New Egypt, high water crest elevations for Crosswicks Creek were approximately 4 feet higher than the previous maximum recorded on August 28, 1971. Total damages were in excess of 2 million dollars, with 70 houses and 14 businesses affected.

  13. Excitatory inputs to four types of spinocerebellar tract neurons in the cat and the rat thoraco-lumbar spinal cord

    PubMed Central

    Shrestha, Sony Shakya; Bannatyne, B Anne; Jankowska, Elzbieta; Hammar, Ingela; Nilsson, Elin; Maxwell, David J

    2012-01-01

    The cerebellum receives information from the hindlimbs through several populations of spinocerebellar tract neurons. Although the role of these neurons has been established in electrophysiological experiments, the relative contribution of afferent fibres and central neurons to their excitatory input has only been estimated approximately so far. Taking advantage of differences in the immunohistochemistry of glutamatergic terminals of peripheral afferents and of central neurons (with vesicular glutamate transporters VGLUT1 or VGLUT2, respectively), we compared sources of excitatory input to four populations of spinocerebellar neurons in the thoraco-lumbar spinal cord: dorsal spinocerebellar tract neurons located in Clarke's column (ccDSCT) and in the dorsal horn (dhDSCT) and ventral spinocerebellar tract (VSCT) neurons including spinal border (SB) neurons. This was done on 22 electrophysiologically identified intracellularly labelled neurons in cats and on 80 neurons labelled by retrograde transport of cholera toxin b subunit injected into the cerebellum of rats. In both species distribution of antibodies against VGLUT1 and VGLUT2 on SB neurons (which have dominating inhibitory input from limb muscles), revealed very few VGLUT1 contacts and remarkably high numbers of VGLUT2 contacts. In VSCT neurons with excitatory afferent input, the number of VGLUT1 contacts was relatively high although VGLUT2 contacts likewise dominated, while the proportions of VGLUT1 and VGLUT2 immunoreactive terminals were the reverse on the two populations of DSCT neurons. These findings provide morphological evidence that SB neurons principally receive excitatory inputs from central neurons and provide the cerebellum with information regarding central neuronal activity. PMID:22371473

  14. Excitatory inputs to four types of spinocerebellar tract neurons in the cat and the rat thoraco-lumbar spinal cord.

    PubMed

    Shrestha, Sony Shakya; Bannatyne, B Anne; Jankowska, Elzbieta; Hammar, Ingela; Nilsson, Elin; Maxwell, David J

    2012-04-01

    The cerebellum receives information from the hindlimbs through several populations of spinocerebellar tract neurons. Although the role of these neurons has been established in electrophysiological experiments, the relative contribution of afferent fibres and central neurons to their excitatory input has only been estimated approximately so far. Taking advantage of differences in the immunohistochemistry of glutamatergic terminals of peripheral afferents and of central neurons (with vesicular glutamate transporters VGLUT1 or VGLUT2, respectively), we compared sources of excitatory input to four populations of spinocerebellar neurons in the thoraco-lumbar spinal cord: dorsal spinocerebellar tract neurons located in Clarke's column (ccDSCT) and in the dorsal horn (dhDSCT) and ventral spinocerebellar tract (VSCT) neurons including spinal border (SB) neurons. This was done on 22 electrophysiologically identified intracellularly labelled neurons in cats and on 80 neurons labelled by retrograde transport of cholera toxin b subunit injected into the cerebellum of rats. In both species distribution of antibodies against VGLUT1 and VGLUT2 on SB neurons (which have dominating inhibitory input from limb muscles), revealed very few VGLUT1 contacts and remarkably high numbers of VGLUT2 contacts. In VSCT neurons with excitatory afferent input, the number of VGLUT1 contacts was relatively high although VGLUT2 contacts likewise dominated, while the proportions of VGLUT1 and VGLUT2 immunoreactive terminals were the reverse on the two populations of DSCT neurons. These findings provide morphological evidence that SB neurons principally receive excitatory inputs from central neurons and provide the cerebellum with information regarding central neuronal activity.

  15. Impact of changes in inspired oxygen and carbon dioxide on respiratory instability in the lamb.

    PubMed

    Wilkinson, Malcolm H; Sia, Kah-Ling; Skuza, Elizabeth M; Brodecky, Vojta; Berger, Philip J

    2005-02-01

    We examined the effect of hypoxia and hypercapnia administered during deliberately induced periodic breathing (PB) in seven lambs following posthyperventilation apnea. Based on our theoretical analysis, the sensitivity or loop gain (LG) of the respiratory control system of the lamb is directly proportional to the difference between alveolar PO2 and inspired PO2. This analysis indicates that during PB, when by necessity LG is >1, replacement of the inspired gas with one of reduced PO2 lowers LG; if we made inspired PO2 approximate alveolar PO2, we predict that LG would be approximately zero and breathing would promptly stabilize. In six lambs, we switched the inspired gas from an inspiratory oxygen fraction of 0.4 to one of 0.12 during an epoch of PB; PB was immediately suppressed, supporting the view that the peripheral chemoreceptors play a pivotal role in the genesis and control of unstable breathing in the lamb. In the six lambs in which we administered hypercapnic gas during PB, breathing instability was also suppressed, but only after a considerable time lag, indicating the CO2 effect is likely to have been mediated through the central chemoreceptors. When we simulated both interventions in a published model of the adult respiratory controller, PB was immediately suppressed by CO2 inhalation and exacerbated by inhalation of hypoxic gas. These fundamentally different responses in lambs and adult humans demonstrate that PB has differing underlying mechanisms in the two species.

  16. Nuclear force from lattice QCD.

    PubMed

    Ishii, N; Aoki, S; Hatsuda, T

    2007-07-13

    The nucleon-nucleon (NN) potential is studied by lattice QCD simulations in the quenched approximation, using the plaquette gauge action and the Wilson quark action on a 32(4) [approximately (4.4 fm)(4)] lattice. A NN potential V(NN)(r) is defined from the equal-time Bethe-Salpeter amplitude with a local interpolating operator for the nucleon. By studying the NN interaction in the (1)S(0) and (3)S(1) channels, we show that the central part of V(NN)(r) has a strong repulsive core of a few hundred MeV at short distances (r approximately < 0.5 fm) surrounded by an attractive well at medium and long distances. These features are consistent with the known phenomenological features of the nuclear force.

  17. Effect of central corneal thickness, corneal curvature, and axial length on applanation tonometry.

    PubMed

    Kohlhaas, Markus; Boehm, Andreas G; Spoerl, Eberhard; Pürsten, Antje; Grein, Hans J; Pillunat, Lutz E

    2006-04-01

    To evaluate the effect of central corneal thickness (CCT), corneal curvature, and axial length on applanation tonometry in an in vivo study. In a masked, prospective clinical trial, we examined 125 eyes of 125 patients scheduled for cataract surgery. Corneal curvature was measured by means of keratometry and axial length by A-scan ultrasonography. By cannulating the anterior chamber before surgery, intraocular pressure (IOP) was set to 20, 35, and 50 mm Hg in a closed system by means of a water column. After measuring thickness, the IOP was measured with an applanation tonometer. Pearson product moment correlations and multiple linear regression analyses were performed, and significance levels were evaluated by the paired, 2-tailed t test. The difference between measured and real IOP was significantly dependent (P < .001) on CCT. The associations between IOP and corneal curvature or IOP and axial length were not statistically significant (P = .31). The association between IOP reading and CCT is shown in the "Dresdner correction table," which illustrates an approximately 1-mm Hg correction for every 25-microm deviation from a CCT of 550 microm. The correction values were positive as thickness decreased and negative as thickness increased. Central corneal thickness significantly affects IOP readings obtained by applanation tonometry according to the Goldmann principle. A correction of IOP readings by considering CCT according to the Dresdner correction table might be helpful for determining an accurate IOP value.

  18. A T-shaped double quantum dot system as a Fano interferometer: Interplay of coherence and correlation upon spin currents

    NASA Astrophysics Data System (ADS)

    Fernandes, I. L.; Cabrera, G. G.

    2018-05-01

    Based on Keldysh non-equilibrium Green function method, we have investigated spin current production in a hybrid T-shaped device, consisting of a central quantum dot connected to the leads and a side dot which only couples to the central dot. The topology of this structure allows for quantum interference of the different paths that go across the device, yielding Fano resonances in the spin dependent transport properties. Correlation effects are taken into account at the central dot and handled within a mean field approximation. Its interplay with the Fano effect is analyzed in the strong coupling regime. Non-vanishing spin currents are only obtained when the leads are ferromagnetic, the current being strongly dependent on the relative orientation of the lead polarizations. We calculate the conductance (spin and charge) by numerically differentiating the current, and a rich structure is obtained as a manifestation of quantum coherence and correlation effects. Increase of the Coulomb interaction produces localization of states at the side dot, largely suppressing Fano resonances. The interaction is also responsible for the negative values of the spin conductance in some regions of the voltage near resonances, effect which is the spin analog of the Esaki tunnel diode. We also analyze control of the currents via gate voltages applied to the dots, possibility which is interesting for practical operations.

  19. Molecular descriptors calculation as a tool in the analysis of the antileishmanial activity achieved by two series of diselenide derivatives. An insight into its potential action mechanism.

    PubMed

    Font, María; Baquedano, Ylenia; Plano, Daniel; Moreno, Esther; Espuelas, Socorro; Sanmartín, Carmen; Palop, Juan Antonio

    2015-07-01

    A molecular modeling study has been carried out on two previously reported series of symmetric diselenide derivatives that show remarkable antileishmanial in vitro activity against Leishmania infantum intracellular amastigotes and in infected macrophages (THP-1 cells), in addition to showing favorable selectivity indices. Series 1 consists of compounds that can be considered as central scaffold constructed with a diaryl/dialkylaryl diselenide central nucleus, decorated with different substituents located on the aryl rings. Series 2 consists of compounds constructed over a diaryl diselenide central nucleus, decorated in 4 and 4' positions with an aryl or heteroaryl sulfonamide fragment, thus forming the diselenosulfonamide derivatives. With regard to the diselenosulfonamide derivatives (2 series), the activity can be related, as a first approximation, with (a) the ability to release bis(4-aminophenyl) diselenide, the common fragment which can be ultimately responsible for the activity of the compounds. (b) the anti-parasitic activity achieved by the sulfonamide pharmacophore present in the analyzed derivatives. The data that support this connection include the topography of the molecules, the conformational behavior of the compounds, which influences the bond order, as well as the accessibility of the hydrolysis point, and possibly the hydrophobicity and polarizability of the compounds. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Breeding phenology and reproductive success of the Brandt's Cormorant at three nearshore colonies in central California, 1997-2001

    USGS Publications Warehouse

    Jones, Nathan M.; McChesney, Gerard; Parker, Michael W.; Yee, Julie L.; Carter, Harry R.; Golightly, Richard T.

    2008-01-01

    Brandt's Cormorant (Phalacrocorax penicillatus) breeding effort, phenology and success were studied in 1997-2001 at three colonies spanning approximately 200 km of the central California coast: Point Reyes (PR); Devil's Slide Rock and Mainland (DS); and Castle-Hurricane Colony Complex (CH). Breeding effort was reduced at all three colonies in the 1998 El Niño event. Mean clutch initiation dates differed significantly among colonies, with cormorants at the southernmost colony (CH) laying earliest, and those at the northernmost colony (PR) laying latest. Productivity at individual colonies varied greatly among years (range 0.7-2.5 fledglings per pair). Overall colony means were lowest (1.6 fledglings/pair) during the 1998 El Niño event and highest (2.5 fledglings/pair) in the 1999 La Niña event. Productivity at CH (1.7 fledglings/pair) was significantly lower than at PR (2.2 fledglings/pair), and interannual variation was greatest at CH. Late-nesting birds laid fewer eggs, hatched fewer chicks, and fledged fewer chicks per pair than early-nesters. The rapid rate of growth at some nearshore colonies in central California suggests immigration from elsewhere, most likely the large offshore colony at the South Farallon Islands. Variation in timing of breeding and reproductive success among colonies demonstrates a value in maintaining multiple study locations when assessing Brandt's Cormorant population parameters in the California Current System.

  1. Photosynthetic fractionation of 13C and concentrations of dissolved CO2 in the central equatorial Pacific during the last 255,000 years

    NASA Technical Reports Server (NTRS)

    Jasper, J. P.; Hayes, J. M.; Mix, A. C.; Prahl, F. G.

    1994-01-01

    Carbon isotopically based estimates of CO2 levels have been generated from a record of the photosynthetic fractionation of 13C [is equivalent to epsilon(p)] in a central equatorial Pacific sediment core that spans the last approximately 255 ka. Contents of 13C in phytoplanktonic biomass were determined by analysis of C37 alkadienones. These compounds are exclusive products of Prymnesiophyte algae which at present grow most abundantly at depths of 70-90 m in the central equatorial Pacific. A record of the isotopic composition of dissolved CO2 was constructed from isotopic analyses of the planktonic foraminifera Neogloboquadrina dutertrei, which calcifies at 70-90 m in the same region. Values of epsilon(p), derived by comparison of the organic and inorganic delta values, were transformed to yield concentrations of dissolved CO2 [is equivalent to c(e)] based on a new, site-specific calibration of the relationship between epsilon(p) and c(e). The calibration was based on reassessment of existing epsilon(p) versus c(e) data, which support a physiologically based model in which epsilon(p) is inversely related to c(e). Values of PCO2, the partial pressure of CO2 that would be in equilibrium with the estimated concentrations of dissolved CO2, were calculated using Henry's law and the temperature determined from the alkenone-unsaturation index U(K/37). Uncertainties in these values arise mainly from uncertainties about the appropriateness (particularly over time) of the site-specific relationship between epsilon(p) and 1/c(e). These are discussed in detail and it is concluded that the observed record of epsilon(p) most probably reflects significant variations in delta pCO2, the ocean-atmosphere disequilibrium, which appears to have ranged from approximately 110 microatmospheres during glacial intervals (ocean > atmosphere) to approximately 60 microatmospheres during interglacials. Fluxes of CO2 to the atmosphere would thus have been significantly larger during glacial intervals. If this were characteristic of large areas of the equatorial Pacific, then greater glacial sinks for the equatorially evaded CO2 must have existed elsewhere. Statistical analysis of air-sea pCO2 differences and other parameters revealed significant (p<0.01) inverse correlations of delta pCO2 with sea surface temperature and with the mass accumulation rate of opal. The former suggests response to the strength of upwelling, the latter may indicate either drawdown of CO2 by siliceous phytoplankton or variation of [CO2]/[Si(OH)4] ratios in upwelling waters.

  2. Unification of Gauge Couplings in the E{sub 6}SSM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Athron, P.; King, S. F.; Luo, R.

    2010-02-10

    We argue that in the two--loop approximation gauge coupling unification in the exceptional supersymmetric standard model (E{sub 6}SSM) can be achieved for any phenomenologically reasonable value of alpha{sub 3}(M{sub Z}) consistent with the experimentally measured central value.

  3. A profile of Wisconsin's private forest landowers

    Treesearch

    Earl C. Leatherberry

    2000-01-01

    In 1997, the USDA Forest Service, & Forest Inventory and Analysis (FIA) Program at the North Central Research Station in St. Paul, Minnesota contacted approximately 3,000 private forest landowners in Wisconsin as part of acomprehensive statewide survey. FIA routinely collects and analyzes forest resources data.

  4. Tabular comparisons of the Flynn Creek impact crater, United States, Steinheim impact crater, Germany and Snowball explosion crater, Canada

    NASA Technical Reports Server (NTRS)

    Roddy, D. J.

    1977-01-01

    A tabular outline of comparative data is presented for 340 basic dimensional, morphological, and structural parameters and related aspects for three craters of the flat-floored, central uplift type, two of which are natural terrestrial impact craters and one is a large-scale experimental explosion crater. The three craters are part of a general class, in terms of their morphology and structural deformation that is represented on each of the terrestrial planets including the moon. One of the considered craters, the Flynn Creek Crater, was formed by a hypervelocity impact event approximately 360 m.y. ago in what is now north central Tennessee. The impacting body appears to have been a carbonaceous chondrite or a cometary mass. The second crater, the Steinheim Crater, was formed by an impact event approximately 14.7 m.y. ago in what is now southwestern Germany. The Snowball Crater was formed by the detonation of a 500-ton TNT hemisphere on flat-lying, unconsolidated alluvium in Alberta, Canada.

  5. Progress in the Biological Understanding and Management of Breast Cancer-Associated Central Nervous System Metastases

    PubMed Central

    Gonzalez-Angulo, Ana M.

    2013-01-01

    Metastasis to the central nervous system (CNS) is a devastating neurological complication of systemic cancer. Brain metastases from breast cancer have been documented to occur in approximately 10%–16% of cases over the natural course of the disease with leptomeningeal metastases occurring in approximately 2%–5% of cases of breast cancer. CNS metastases among women with breast cancer tend to occur among those who are younger, have larger tumors, and have a more aggressive histological subtype such as the triple negative and HER2-positive subtypes. Treatment of CNS metastases involves various combinations of whole brain radiation therapy, surgery, stereotactic radiosurgery, and chemotherapy. We will discuss the progress made in the treatment and prevention of breast cancer-associated CNS metastases and will delve into the biological underpinnings of CNS metastases including evaluating the role of breast tumor subtype on the incidence, natural history, prognostic outcome, and impact of therapeutic efficacy. PMID:23740934

  6. Zero absolute vorticity: insight from experiments in rotating laminar plane Couette flow.

    PubMed

    Suryadi, Alexandre; Segalini, Antonio; Alfredsson, P Henrik

    2014-03-01

    For pressure-driven turbulent channel flows undergoing spanwise system rotation, it has been observed that the absolute vorticity, i.e., the sum of the averaged spanwise flow vorticity and system rotation, tends to zero in the central region of the channel. This observation has so far eluded a convincing theoretical explanation, despite experimental and numerical evidence reported in the literature. Here we show experimentally that three-dimensional laminar structures in plane Couette flow, which appear under anticyclonic system rotation, give the same effect, namely, that the absolute vorticity tends to zero if the rotation rate is high enough. It is shown that this is equivalent to a local Richardson number of approximately zero, which would indicate a stable condition. We also offer an explanation based on Kelvin's circulation theorem to demonstrate that the absolute vorticity should remain constant and approximately equal to zero in the central region of the channel when going from the nonrotating fully turbulent state to any state with sufficiently high rotation.

  7. Mathematical formalisms based on approximated kinetic representations for modeling genetic and metabolic pathways.

    PubMed

    Alves, Rui; Vilaprinyo, Ester; Hernádez-Bermejo, Benito; Sorribas, Albert

    2008-01-01

    There is a renewed interest in obtaining a systemic understanding of metabolism, gene expression and signal transduction processes, driven by the recent research focus on Systems Biology. From a biotechnological point of view, such a systemic understanding of how a biological system is designed to work can facilitate the rational manipulation of specific pathways in different cell types to achieve specific goals. Due to the intrinsic complexity of biological systems, mathematical models are a central tool for understanding and predicting the integrative behavior of those systems. Particularly, models are essential for a rational development of biotechnological applications and in understanding system's design from an evolutionary point of view. Mathematical models can be obtained using many different strategies. In each case, their utility will depend upon the properties of the mathematical representation and on the possibility of obtaining meaningful parameters from available data. In practice, there are several issues at stake when one has to decide which mathematical model is more appropriate for the study of a given problem. First, one needs a model that can represent the aspects of the system one wishes to study. Second, one must choose a mathematical representation that allows an accurate analysis of the system with respect to different aspects of interest (for example, robustness of the system, dynamical behavior, optimization of the system with respect to some production goal, parameter value determination, etc). Third, before choosing between alternative and equally appropriate mathematical representations for the system, one should compare representations with respect to easiness of automation for model set-up, simulation, and analysis of results. Fourth, one should also consider how to facilitate model transference and re-usability by other researchers and for distinct purposes. Finally, one factor that is important for all four aspects is the regularity in the mathematical structure of the equations because it facilitates computational manipulation. This regularity is a mark of kinetic representations based on approximation theory. The use of approximation theory to derive mathematical representations with regular structure for modeling purposes has a long tradition in science. In most applied fields, such as engineering and physics, those approximations are often required to obtain practical solutions to complex problems. In this paper we review some of the more popular mathematical representations that have been derived using approximation theory and are used for modeling in molecular systems biology. We will focus on formalisms that are theoretically supported by the Taylor Theorem. These include the Power-law formalism, the recently proposed (log)linear and Lin-log formalisms as well as some closely related alternatives. We will analyze the similarities and differences between these formalisms, discuss the advantages and limitations of each representation, and provide a tentative "road map" for their potential utilization for different problems.

  8. A computerized aircraft battery servicing facility

    NASA Technical Reports Server (NTRS)

    Glover, Richard D.

    1992-01-01

    The latest upgrade to the Aerospace Energy Systems Laboratory (AESL) is described. The AESL is a distributed digital system consisting of a central system and battery servicing stations connected by a high-speed serial data bus. The entire system is located in two adjoining rooms; the bus length is approximately 100 ft. Each battery station contains a digital processor, data acquisition, floppy diskette data storage, and operator interfaces. The operator initiates a servicing task and thereafter the battery station monitors the progress of the task and terminates it at the appropriate time. The central system provides data archives, manages the data bus, and provides a timeshare interface for multiple users. The system also hosts software production tools for the battery stations and the central system.

  9. 2011 Annual Wastewater Reuse Report for the Idaho National Laboratory Site’s Central Facilities Area Sewage Treatment Plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Michael G. Lewis

    2012-02-01

    This report describes conditions, as required by the state of Idaho Wastewater Reuse Permit (LA-000141-03), for the wastewater land application site at Idaho National Laboratory Site's Central Facilities Area Sewage Treatment Plant from November 1, 2010, through October 31, 2011. The report contains the following information: (1) Site description; (2) Facility and system description; (3) Permit required monitoring data and loading rates; (4) Status of special compliance conditions and activities; and (5) Discussion of the facility's environmental impacts. During the 2011 permit year, approximately 1.22 million gallons of treated wastewater was land-applied to the irrigation area at Central Facilities Areamore » Sewage Treatment plant.« less

  10. Soft, Rotating Pneumatic Actuator.

    PubMed

    Ainla, Alar; Verma, Mohit S; Yang, Dian; Whitesides, George M

    2017-09-01

    This article describes a soft pneumatic actuator that generates cyclical motion. The actuator consists of several (three, four, or five) chambers (arranged around the circumference of a circle surrounding a central rod) that can be actuated independently using negative pressure (or partial vacuum). Sequential actuation of the four-chamber device using reduced pressure moves the central rod cyclically in an approximately square path. We characterize the trajectory of the actuator and the force exerted by it, as we vary the material used for fabrication, the number of chambers, and the size of the actuator. We demonstrate two applications of this actuator: to deliver fluid while stirring (by replacing the central rod with a needle) and for locomotion that mimics a reptilian gait (by combining four actuators together).

  11. An upwind space-time conservation element and solution element scheme for solving dusty gas flow model

    NASA Astrophysics Data System (ADS)

    Rehman, Asad; Ali, Ishtiaq; Qamar, Shamsul

    An upwind space-time conservation element and solution element (CE/SE) scheme is extended to numerically approximate the dusty gas flow model. Unlike central CE/SE schemes, the current method uses the upwind procedure to derive the numerical fluxes through the inner boundary of conservation elements. These upwind fluxes are utilized to calculate the gradients of flow variables. For comparison and validation, the central upwind scheme is also applied to solve the same dusty gas flow model. The suggested upwind CE/SE scheme resolves the contact discontinuities more effectively and preserves the positivity of flow variables in low density flows. Several case studies are considered and the results of upwind CE/SE are compared with the solutions of central upwind scheme. The numerical results show better performance of the upwind CE/SE method as compared to the central upwind scheme.

  12. Degree-Pruning Dynamic Programming Approaches to Central Time Series Minimizing Dynamic Time Warping Distance.

    PubMed

    Sun, Tao; Liu, Hongbo; Yu, Hong; Chen, C L Philip

    2016-06-28

    The central time series crystallizes the common patterns of the set it represents. In this paper, we propose a global constrained degree-pruning dynamic programming (g(dp)²) approach to obtain the central time series through minimizing dynamic time warping (DTW) distance between two time series. The DTW matching path theory with global constraints is proved theoretically for our degree-pruning strategy, which is helpful to reduce the time complexity and computational cost. Our approach can achieve the optimal solution between two time series. An approximate method to the central time series of multiple time series [called as m_g(dp)²] is presented based on DTW barycenter averaging and our g(dp)² approach by considering hierarchically merging strategy. As illustrated by the experimental results, our approaches provide better within-group sum of squares and robustness than other relevant algorithms.

  13. Diffracted field distributions from the HE11 mode in a hollow optical fibre for an atomic funnel

    NASA Astrophysics Data System (ADS)

    Ni, Yun; Liu, Nanchun; Yin, Jianping

    2003-06-01

    The diffracted near field distribution from an LP01 mode in a hollow optical fibre was recently calculated using a scalar model based on the weakly waveguiding approximation (Yoo et al 1999 J. Opt. B: Quantum Semiclass. Opt. 1 364). It showed a dominant Gaussian-like distribution with an increased axial intensity in the central region (not a doughnut-like distribution), so the diffracted output beam from the hollow fibre cannot be used to form an atomic funnel. Using exact solutions of the Maxwell equations based on a vector model, however, we calculate the electric field and intensity distributions of the HE11 mode in the same hollow fibre and study the diffracted near- and far-field distributions of the HE11-mode output beam under the Fresnel approximation. We analyse and compare the differences between the output beams from the HE11 and LP01 modes. Our study shows that both the near- and far-field intensity distributions of the HE11-mode output beam are doughnut-like and can be used to form a simple atomic funnel. However, it is not suitable to use the weakly waveguiding approximation to calculate the diffracted near-field distribution of the hollow fibre due to the greater refractive-index difference between the hollow region (n0 = 1) and the core (n1 = 1.45 or 1.5). Finally, the 3D intensity distribution of the HE11-mode output beam is modelled and the corresponding optical potentials for cold atoms are calculated. Some potential applications of the HE11-mode output beam in an atomic guide and funnel are briefly discussed.

  14. A summary of the geology and petrology of the Sierra La Primavera, Jalisco, Mexico

    NASA Astrophysics Data System (ADS)

    Mahood, Gail A.

    1981-11-01

    The Sierra La Primavera, near Guadalajara, Mexico, is a Late Pleistocene rhyolitic center consisting of lava flows and domes, ash flow tuff, air fall pumice, and caldera lake sediments. All eruptive units are high-silica rhyolites, but systematic compositional differences correlate with age and eruptive mode. The earliest lavas erupted approximately 145,000 years ago and were followed approximately 95,000 years ago by the eruption of about 20 km3 of magma as ash flows that form the Tala Tuff. The Tala Tuff is zoned from a mildly peralkaline first-erupted portion enriched in Na, Rb, Cs, Cl, F, Zn, Y, Zr, Nb, Sb, HREE, Hf, Ta, Pb, Th, and U to a metaluminous last-erupted part enriched in K, LREE, Sc, and Ti; Al, Ca, Mg, Mn, Fe, and Eu are constant within analytical errors. Collapse of the roof zone of the magma chamber led to the formation of a shallow 11-km-diameter caldera in which lake sediments began to collect. The earliest postcaldera lava, the south-central dome, is nearly identical to the last-erupted portion of the Tala Tuff, whereas the slightly younger north-central dome is chemically transitional from the south-central dome to later, more mafic, ring domes. This sequence of ash flow tuff and domes represents the tapping of progressively deeper levels of a zoned magma chamber 95,000 ± 5,000 years ago. Sedimentation continued and a period of volcanic quiescence was marked by the deposition of some 30 m of fine-grained ashy sediments. Approximately 75,000 years ago a new group of ring domes erupted at the southern margin of the lake. These domes are lapped by only 10-20 m of sediments as uplift resulting from renewed insurgence of magma brought an end to the lake. This uplift culminated in the eruption, beginning approximately 60,000 years ago, of aphyric lavas along a southern arc. The youngest of these lavas erupted approximately 30,000 years ago. The lavas that erupted 75,000, 60,000, and 30,000 years ago became decreasingly peralkaline and progressively enriched only in Si, Rb, Cs, and possibly U with time. They represent successive eruption of the uppermost magma in the postcaldera magma chamber. Eruptive units of La Primavera are either aphyric or contain up to 15% phenocrysts of sodic sanidine ≥ quartz ≫ ferrohedenbergite > fayalite > ilmenite ± titanomagnetite. Major element compositions of sanidine, clinopyroxene, and fayalite phenocrysts vary only slightly between eruptive groups, but the concentrations of many trace elements change by factors of 5-10. This is reflected in phenocryst/glass partition coefficients that differ by factors of up to 20 between successively erupted units. Because the major element compositions of the phenocrysts and the pressure, temperature, and ƒO2 of the magmas were essentially constant, the large variations in partitioning behavior are thought to result from small changes in bulk composition of the melt. Crystal settling and incremental partial melting are by themselves incapable of producing either the chemical gradients within the Tala Tuff magma chamber or the trends with time in the post-95,000-year lavas. Rather, diffusional processes in the silicate liquid are thought to have been the dominant differentiation mechanisms. The zonation in the Tala Tuff is attributed to transport of trace metals as volatile complexes within a thermal and gravitational gradient in a volatile-rich but water-undersaturated magma. The evolution of the postcaldera lavas with time is thought to involve the diffusive emigration of trace elements from a relatively dry magma as a decreasing proportion of network modifiers and/or a decreasing concentration of complexing ligands progressively reduced octahedral site availability in the silicate melt.

  15. The Dense Gas Fraction in the Central Molecular Zone in the Milky Way

    NASA Astrophysics Data System (ADS)

    Vargas-Salazar, Irene; Battersby, Cara; Walker, Daniel; Zhang, Qizhou; CMZoom

    2017-01-01

    The Central Molecular Zone (CMZ), a large reservoir of dense molecular gas occupying the central 500pc of the Milky Way, is an extreme star-formation environment where the validity of star formation prescriptions can be tested. The star formation rate (SFR) in the CMZ is about an order of magnitude lower than predicted by the currently accepted prescriptions. An international team lead by PIs Battersby and Keto conducted a survey from 2013-2016 called CMZoom using the Submillimeter Array (SMA) to characterize star formation within resolved molecular clouds in this extreme region. One of the main goals of this survey is to further quantify and understand the low SFR found in this region of the Galaxy. Here, we use the CASA software package to run synthetic observations of hydrodynamical simulations of molecular clouds and vary the observation parameters in such a way that we explore the real parameter space that was probed during the survey. The purpose of this is to investigate how the different observational parameters affect the resultant data. Afterwards, we estimate the “dense gas fraction” (DGF) found in regions across the CMZ. This estimate was found by using the interferometric flux from SMA and the single-dish flux from the Bolocam Galactic Plane Survey. We analyzed the effects that different locations of the CMZ had on these approximate DGF. With these simulations and DGF estimates, we are able to generate improved methods to analyze the data from this survey that will help understand star formation in an extreme environment.The SAO REU program is funded in part by the National Science Foundation REU and Department of Defense ASSURE programs under NSF Grant no.1262851, and by the Smithsonian Institution.

  16. Age, Sex, and Ethnic Variations in Inner and Outer Retinal and Choroidal Thickness on Spectral-Domain Optical Coherence Tomography.

    PubMed

    Bafiq, Rinoza; Mathew, Raeba; Pearce, Elizabeth; Abdel-Hey, Ahmed; Richardson, Matthew; Bailey, Thomas; Sivaprasad, Sobha

    2015-11-01

    To evaluate age, sex, and ethnic variations in inner and outer retinal and choroidal thickness and foveal pit, using spectral-domain optical coherence tomography (SD OCT). Single-center observational cross-sectional study. Ninety randomly selected, healthy individuals of white, black, and South Asian origin underwent SD OCT raster and enhanced depth imaging scan. Manual measurements of inner and outer retinal thickness and choroidal thickness up to 3 mm nasal and temporal to the fovea were performed. The age, sex, and ethnic differences in these parameters were analyzed. The mean inner retinal thickness was lower by approximately 12 μm in black subjects across the central retina compared to white subjects (P < .05). The central foveal thickness below the foveal pit was lower in eyes of blacks compared to South Asians (12 μm, P = .035) and white subjects (18 μm, P < .0001). The fovea was also significantly wider in eyes of black and South Asian subjects compared to white individuals. The inner retinal thickness decreased by 0.5 μm per year of age of subjects and was thinner by 6.1 μm (P < .02) in female compared to male subjects. The subfoveal choroidal thickness did not vary between ethnic groups but the temporal choroid was significantly thinner in black subjects (P < .05). The choroid showed an age-related decline in thickness of 2 μm per year of age of the subjects. Interethnic differences include wider fovea, lower central foveal thickness, and thinner inner retina in eyes of black subjects compared to their white and South Asian counterparts. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. The planetary nebula IC 4776 and its post-common-envelope binary central star

    NASA Astrophysics Data System (ADS)

    Sowicka, Paulina; Jones, David; Corradi, Romano L. M.; Wesson, Roger; García-Rojas, Jorge; Santander-García, Miguel; Boffin, Henri M. J.; Rodríguez-Gil, Pablo

    2017-11-01

    We present a detailed analysis of IC 4776, a planetary nebula displaying a morphology believed to be typical of central star binarity. The nebula is shown to comprise a compact hourglass-shaped central region and a pair of precessing jet-like structures. Time-resolved spectroscopy of its central star reveals a periodic radial velocity variability consistent with a binary system. Whilst the data are insufficient to accurately determine the parameters of the binary, the most likely solutions indicate that the secondary is probably a low-mass main-sequence star. An empirical analysis of the chemical abundances in IC 4776 indicates that the common-envelope phase may have cut short the asymptotic giant branch evolution of the progenitor. Abundances calculated from recombination lines are found to be discrepant by a factor of approximately 2 relative to those calculated using collisionally excited lines, suggesting a possible correlation between low-abundance discrepancy factors and intermediate-period post-common-envelope central stars and/or Wolf-Rayet central stars. The detection of a radial velocity variability associated with the binarity of the central star of IC 4776 may be indicative of a significant population of (intermediate-period) post-common-envelope binary central stars that would be undetected by classic photometric monitoring techniques.

  18. A profile of Wisconsin''s private forest landowners

    Treesearch

    Earl C. Leatherberry

    2001-01-01

    In 1997, the USDA Forest Service, Forest Inventory and Analysis (FIA) Program at the North Central Research Station in St. Paul, Minnesota contacted approximately 3,000 private forest landowners in Wisconsin as part of a comprehensive statewide survey. FIA routinely collects and analyzes forest resources data.

  19. Pleistocene refugia and polytopic replacement of diploids by tetraploids in the Patagonian and Subantarctic plant Hypochaeris incana (Asteraceae, Cichorieae).

    PubMed

    Tremetsberger, Karin; Urtubey, Estrella; Terrab, Anass; Baeza, Carlos M; Ortiz, María Angeles; Talavera, María; König, Christiane; Temsch, Eva M; Kohl, Gudrun; Talavera, Salvador; Stuessy, Tod F

    2009-09-01

    We report the phylogeographic pattern of the Patagonian and Subantarctic plant Hypochaeris incana endemic to southeastern South America. We applied amplified fragment length polymorphism (AFLP) and chloroplast DNA (cpDNA) analysis to 28 and 32 populations, respectively, throughout its distributional range and assessed ploidy levels using flow cytometry. While cpDNA data suggest repeated or simultaneous parallel colonization of Patagonia and Tierra del Fuego by several haplotypes and/or hybridization, AFLPs reveal three clusters corresponding to geographic regions. The central and northern Patagonian clusters (approximately 38-51 degrees S), which are closer to the outgroup, contain mainly tetraploid, isolated and highly differentiated populations with low genetic diversity. To the contrary, the southern Patagonian and Fuegian cluster (approximately 51-55 degrees S) contains mainly diploid populations with high genetic diversity and connected by high levels of gene flow. The data suggest that H. incana originated at the diploid level in central or northern Patagonia, from where it migrated south. All three areas, northern, central and southern, have similar levels of rare and private AFLP bands, suggesting that all three served as refugia for H. incana during glacial times. In southern Patagonia and Tierra del Fuego, the species seems to have expanded its populational system in postglacial times, when the climate became warmer and more humid. In central and northern Patagonia, the populations seem to have become restricted to favourable sites with increasing temperature and decreasing moisture and there was a parallel replacement of diploids by tetraploids in local populations.

  20. Periodontal disease awareness among pregnant women in the central and eastern regions of Saudi Arabia.

    PubMed

    Asa'ad, Farah A; Rahman, Ghousia; Al Mahmoud, Noura; Al Shamasi, Ebtehaj; Al Khuwaileidi, Abrar

    2015-02-01

    The purpose of this study was to assess the knowledge and awareness regarding periodontal disease and its effects on pregnancy among pregnant women in the central and eastern regions of Saudi Arabia. In this cross-sectional survey, self-administered, structured questionnaires were distributed to 300 pregnant women who were chosen randomly from attendees of maternity health care centers in the central and eastern regions of Saudi Arabia. The questions were developed from literature reviews of articles. The questionnaire addressed personal and sociodemographic variables, periodontal health awareness, and knowledge of pregnant women. The questionnaire was translated into Arabic and was pretested during the pilot study on a random sample of 50 pregnant women. Data were analyzed by χ(2) -tests, with the level of significance set at P < 0.05. An overall response rate of 81% was obtained. Approximately 53% had a higher level of education, but only 21% knew how to define dental plaque and 30% knew its harmful effects. Almost 73% stated that gum disease could be prevented through toothbrushing and flossing. Approximately 97% of the respondents knew the negative effect of smoking, while only 12% knew there was a possible relationship between periodontal disease and adverse pregnancy outcomes. The results of this cross-sectional study found that there is limited knowledge and awareness about periodontal disease and its possible effects on pregnancy among pregnant women attending maternal health care centers in the central and eastern regions of Saudi Arabia. © 2013 Wiley Publishing Asia Pty Ltd.

  1. Detection and mapping of mineralized areas in the Cortez-Uinta Belt, Utah-Nevada, using computer-enhanced ERTS imagery

    NASA Technical Reports Server (NTRS)

    Rowan, L. C. (Principal Investigator)

    1976-01-01

    The author has identified the following significant results. Preliminary analysis indicates that mineralogical differences between altered rocks and most unaltered rocks in south-central Nevada cause visible and near infrared spectral reflectance differences, which can be used to discriminate these broad categories of rocks in multispectral images. The most important mineralogical differences are the increased abundance of goethite, hematite, and jarosite, and the presence of alunite, montmorillonite, and kaolinite in the altered rock. The technique to enhance subtle spectral differences combines ratioing of the MSS bands and contrast stretching. The stretched ratio values are used to produce black and white images that depict materials according to spectral reflectance; rationing minimizes the influence of topography and overall albedo on the grouping of spectrally similar materials. Field evaluation of color-ratio composite shows that, excluding alluvial areas, approximately 80 percent of the green and brown color patterns are related to hydrothermal alternation. The remaining 20 percent consists mainly of pink hematitic crystallized tuff, a result of vapor phase crystallization, and of tan and red ferruginous shale and siltstone.

  2. Cooling and inferred uplift/erosion history of the Grenville Orogen, Ontario: Constraints from sup 40 Ar/ sup 39 Ar thermochronology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cosca, M.A.

    1989-01-01

    Thermochronological ({sup 40}Ar/{sup 39}Ar) data are presented from 76 mineral separates of hornblende, muscovite, biotite, phlogopite, and K-feldspar. Samples were selected from regionally metamorphosed gneiss, amphibolite, metasediment, marble, metagabbro and pegmatite across the two major metamorphic belts of the Grenville Province, the Central Metasedimentary Belt (CMB) and the Central Gneiss Belt (CGB). When combined with published temperature estimates for closure to argon diffusion in the phases analyzed, cooling rates from {approximately}500 C to {approximately}120 C of 1-4 C/MA are calculated across the entire Grenville Province of Ontario. Regional uplift/erosion rates for the Grenville Orogen of Ontario have been estimated frommore » the {sup 40}Ar/{sup 39}Ar data, a retrograde P-T path for rocks of the CGB, and an upper time constraint provided by flat, overlying Cambro-Ordovician sediments. Twenty-two of the hornblendes used for thermochronology have been quantitatively analyzed for major elements by microprobe, Fe{sup 2+}/Fe{sup 3+} by wet chemistry, and for H{sub 2}O by manometric measurement. Water activities calculated from hornblende equilibria are typically low (<0.01) because of the exponential dilutions in hornblende (tremolite) activity required by present activity-composition models. An oxyamphibole component of 25% further reduces any amphibole component and the H{sub 2}O activity by as much as 50% below that calculated with simplifying assumption. These findings indicate that different amphibole normalization schemes have a marked effect on the activity calculated for a specific amphibole or H{sub 2}O, and should be carefully evaluated.« less

  3. Functional and neurochemical characterization of angiotensin type 1A receptor-expressing neurons in the nucleus of the solitary tract of the mouse.

    PubMed

    Carter, D A; Choong, Y-T; Connelly, A A; Bassi, J K; Hunter, N O; Thongsepee, N; Llewellyn-Smith, I J; Fong, A Y; McDougall, S J; Allen, A M

    2017-10-01

    Angiotensin II acts via two main receptors within the central nervous system, with the type 1A receptor (AT 1A R) most widely expressed in adult neurons. Activation of the AT 1 R in the nucleus of the solitary tract (NTS), the principal nucleus receiving central synapses of viscerosensory afferents, modulates cardiovascular reflexes. Expression of the AT 1 R occurs in high density within the NTS of most mammals, including humans, but the fundamental electrophysiological and neurochemical characteristics of the AT 1A R-expressing NTS neurons are not known. To address this, we have used a transgenic mouse, in which the AT 1A R promoter drives expression of green fluorescent protein (GFP). Approximately one-third of AT 1A R-expressing neurons express the catecholamine-synthetic enzyme tyrosine hydroxylase (TH), and a subpopulation of these stained for the transcription factor paired-like homeobox 2b (Phox2b). A third group, comprising approximately two-thirds of the AT 1A R-expressing NTS neurons, showed Phox2b immunoreactivity alone. A fourth group in the ventral subnucleus expressed neither TH nor Phox2b. In whole cell recordings from slices in vitro, AT 1A R-GFP neurons exhibited voltage-activated potassium currents, including the transient outward current and the M-type potassium current. In two different mouse strains, both AT 1A R-GFP neurons and TH-GFP neurons showed similar AT 1A R-mediated depolarizing responses to superfusion with angiotensin II. These data provide a comprehensive description of AT 1A R-expressing neurons in the NTS and increase our understanding of the complex actions of this neuropeptide in the modulation of viscerosensory processing. Copyright © 2017 the American Physiological Society.

  4. Fully decoupled monolithic projection method for natural convection problems

    NASA Astrophysics Data System (ADS)

    Pan, Xiaomin; Kim, Kyoungyoun; Lee, Changhoon; Choi, Jung-Il

    2017-04-01

    To solve time-dependent natural convection problems, we propose a fully decoupled monolithic projection method. The proposed method applies the Crank-Nicolson scheme in time and the second-order central finite difference in space. To obtain a non-iterative monolithic method from the fully discretized nonlinear system, we first adopt linearizations of the nonlinear convection terms and the general buoyancy term with incurring second-order errors in time. Approximate block lower-upper decompositions, along with an approximate factorization technique, are additionally employed to a global linearly coupled system, which leads to several decoupled subsystems, i.e., a fully decoupled monolithic procedure. We establish global error estimates to verify the second-order temporal accuracy of the proposed method for velocity, pressure, and temperature in terms of a discrete l2-norm. Moreover, according to the energy evolution, the proposed method is proved to be stable if the time step is less than or equal to a constant. In addition, we provide numerical simulations of two-dimensional Rayleigh-Bénard convection and periodic forced flow. The results demonstrate that the proposed method significantly mitigates the time step limitation, reduces the computational cost because only one Poisson equation is required to be solved, and preserves the second-order temporal accuracy for velocity, pressure, and temperature. Finally, the proposed method reasonably predicts a three-dimensional Rayleigh-Bénard convection for different Rayleigh numbers.

  5. A computer program for the geometrically nonlinear static and dynamic analysis of arbitrarily loaded shells of revolution, theory and users manual

    NASA Technical Reports Server (NTRS)

    Ball, R. E.

    1972-01-01

    A digital computer program known as SATANS (static and transient analysis, nonlinear, shells) for the geometrically nonlinear static and dynamic response of arbitrarily loaded shells of revolution is presented. Instructions for the preparation of the input data cards and other information necessary for the operation of the program are described in detail and two sample problems are included. The governing partial differential equations are based upon Sanders' nonlinear thin shell theory for the conditions of small strains and moderately small rotations. The governing equations are reduced to uncoupled sets of four linear, second order, partial differential equations in the meridional and time coordinates by expanding the dependent variables in a Fourier sine or cosine series in the circumferential coordinate and treating the nonlinear modal coupling terms as pseudo loads. The derivatives with respect to the meridional coordinate are approximated by central finite differences, and the displacement accelerations are approximated by the implicit Houbolt backward difference scheme with a constant time interval. The boundaries of the shell may be closed, free, fixed, or elastically restrained. The program is coded in the FORTRAN 4 language and is dimensioned to allow a maximum of 10 arbitrary Fourier harmonics and a maximum product of the total number of meridional stations and the total number of Fourier harmonics of 200. The program requires 155,000 bytes of core storage.

  6. RATIONAL SPLINE SUBROUTINES

    NASA Technical Reports Server (NTRS)

    Schiess, J. R.

    1994-01-01

    Scientific data often contains random errors that make plotting and curve-fitting difficult. The Rational-Spline Approximation with Automatic Tension Adjustment algorithm lead to a flexible, smooth representation of experimental data. The user sets the conditions for each consecutive pair of knots:(knots are user-defined divisions in the data set) to apply no tension; to apply fixed tension; or to determine tension with a tension adjustment algorithm. The user also selects the number of knots, the knot abscissas, and the allowed maximum deviations from line segments. The selection of these quantities depends on the actual data and on the requirements of a particular application. This program differs from the usual spline under tension in that it allows the user to specify different tension values between each adjacent pair of knots rather than a constant tension over the entire data range. The subroutines use an automatic adjustment scheme that varies the tension parameter for each interval until the maximum deviation of the spline from the line joining the knots is less than or equal to a user-specified amount. This procedure frees the user from the drudgery of adjusting individual tension parameters while still giving control over the local behavior of the spline The Rational Spline program was written completely in FORTRAN for implementation on a CYBER 850 operating under NOS. It has a central memory requirement of approximately 1500 words. The program was released in 1988.

  7. Using NDVI to assess vegetative land cover change in central Puget Sound.

    PubMed

    Morawitz, Dana F; Blewett, Tina M; Cohen, Alex; Alberti, Marina

    2006-03-01

    We used the Normalized Difference Vegetation Index (NDVI) in the rapidly growing Puget Sound region over three 5-year time blocks between 1986-1999 at three spatial scales in 42 Watershed Administrative Units (WAUs) to assess changes in the amounts and patterns of green vegetation. On average, approximately 20% of the area in each WAU experienced significant NDVI change over each 5-year time block. Cumulative NDVI change over 15 years (summing change over each 5-year time block) was an average of approximately 60% of each WAU, but was as high as 100% in some. At the regional scale, seasonal weather patterns and green-up from logging were the primary drivers of observed increases in NDVI values. At the WAU scale, anthropogenic factors were important drivers of both positive and negative NDVI change. For example, population density was highly correlated with negative NDVI change over 15 years (r = 0.66, P < 0.01), as was road density (r = 0.71, P < 0.01). At the smallest scale (within 3 case study WAUs) land use differences such as preserving versus harvesting forest lands drove vegetation change. We conclude that large areas within most watersheds are continually and heavily impacted by the high levels of human use and development over short time periods. Our results indicate that varying patterns and processes can be detected at multiple scales using changes in NDVIa values.

  8. Influence of ancient glacial periods on the Andean fauna: the case of the pampas cat (Leopardus colocolo)

    PubMed Central

    Cossíos, Daniel; Lucherini, Mauro; Ruiz-García, Manuel; Angers, Bernard

    2009-01-01

    Background While numerous studies revealed the major role of environmental changes of the Quaternary on the evolution of biodiversity, research on the influence of that period on current South-American fauna is scarce and have usually focused on lowland regions. In this study, the genetic structure of the pampas cat (Leopardus colocolo), a widely distributed felid, was determined and linked to ancient climate fluctuations on the Andean region. Results Using both mitochondrial sequences and nuclear microsatellites, we inferred the existence of at least four groups of populations in the central Andes, while other three localities, with little sample sizes (n = 3), presented differences in only one of these markers. The distribution of these groups is correlated to latitude, with a central area characterized by admixture of numerous mitochondrial clades. This suggests colonization from at least three glacial refuges and a contact zone between 20 degrees and 23 degrees S following a glaciation event. The similar coalescence times of the mitochondrial haplotypes indicated that the major clades split approximately one million years ago, likely during the Pre-Pastonian glacial period (0.80 – 1.30 MYA), followed by a demographic expansion in every clade during the Aftonian interglacial period (0.45 – 0.62 MYA). Interestingly, this structure roughly corresponds to the current recognised distribution of morphological subspecies. Conclusion The four groups of populations identified here must be considered different management units, and we propose the three localities showing differences in only mtDNA or ncDNA as provisional management units. The results revealed the influence of ancient climate fluctuations on the evolutionary history of this species. It is expected that the other species of land vertebrates with a smaller or similar mobility have been affected in the same manner by the glacial and interglacial periods in the central Andes PMID:19331650

  9. A Genome-Wide Analysis of Populations from European Russia Reveals a New Pole of Genetic Diversity in Northern Europe

    PubMed Central

    Khrunin, Andrey V.; Khokhrin, Denis V.; Filippova, Irina N.; Esko, Tõnu; Nelis, Mari; Bebyakova, Natalia A.; Bolotova, Natalia L.; Klovins, Janis; Nikitina-Zake, Liene; Rehnström, Karola; Ripatti, Samuli; Schreiber, Stefan; Franke, Andre; Macek, Milan; Krulišová, Veronika; Lubinski, Jan; Metspalu, Andres; Limborska, Svetlana A.

    2013-01-01

    Several studies examined the fine-scale structure of human genetic variation in Europe. However, the European sets analyzed represent mainly northern, western, central, and southern Europe. Here, we report an analysis of approximately 166,000 single nucleotide polymorphisms in populations from eastern (northeastern) Europe: four Russian populations from European Russia, and three populations from the northernmost Finno-Ugric ethnicities (Veps and two contrast groups of Komi people). These were compared with several reference European samples, including Finns, Estonians, Latvians, Poles, Czechs, Germans, and Italians. The results obtained demonstrated genetic heterogeneity of populations living in the region studied. Russians from the central part of European Russia (Tver, Murom, and Kursk) exhibited similarities with populations from central–eastern Europe, and were distant from Russian sample from the northern Russia (Mezen district, Archangelsk region). Komi samples, especially Izhemski Komi, were significantly different from all other populations studied. These can be considered as a second pole of genetic diversity in northern Europe (in addition to the pole, occupied by Finns), as they had a distinct ancestry component. Russians from Mezen and the Finnic-speaking Veps were positioned between the two poles, but differed from each other in the proportions of Komi and Finnic ancestries. In general, our data provides a more complete genetic map of Europe accounting for the diversity in its most eastern (northeastern) populations. PMID:23505534

  10. Phenotypic covariance at species’ borders

    PubMed Central

    2013-01-01

    Background Understanding the evolution of species limits is important in ecology, evolution, and conservation biology. Despite its likely importance in the evolution of these limits, little is known about phenotypic covariance in geographically marginal populations, and the degree to which it constrains, or facilitates, responses to selection. We investigated phenotypic covariance in morphological traits at species’ borders by comparing phenotypic covariance matrices (P), including the degree of shared structure, the distribution of strengths of pair-wise correlations between traits, the degree of morphological integration of traits, and the ranks of matricies, between central and marginal populations of three species-pairs of coral reef fishes. Results Greater structural differences in P were observed between populations close to range margins and conspecific populations toward range centres, than between pairs of conspecific populations that were both more centrally located within their ranges. Approximately 80% of all pair-wise trait correlations within populations were greater in the north, but these differences were unrelated to the position of the sampled population with respect to the geographic range of the species. Conclusions Neither the degree of morphological integration, nor ranks of P, indicated greater evolutionary constraint at range edges. Characteristics of P observed here provide no support for constraint contributing to the formation of these species’ borders, but may instead reflect structural change in P caused by selection or drift, and their potential to evolve in the future. PMID:23714580

  11. Group Independent Component Analysis (gICA) and Current Source Density (CSD) in the study of EEG in ADHD adults.

    PubMed

    Ponomarev, Valery A; Mueller, Andreas; Candrian, Gian; Grin-Yatsenko, Vera A; Kropotov, Juri D

    2014-01-01

    To investigate the performance of the spectral analysis of resting EEG, Current Source Density (CSD) and group independent components (gIC) in diagnosing ADHD adults. Power spectra of resting EEG, CSD and gIC (19 channels, linked ears reference, eyes open/closed) from 96 ADHD and 376 healthy adults were compared between eyes open and eyes closed conditions, and between groups of subjects. Pattern of differences in gIC and CSD spectral power between conditions was approximately similar, whereas it was more widely spatially distributed for EEG. Size effect (Cohen's d) of differences in gIC and CSD spectral power between groups of subjects was considerably greater than in the case of EEG. Significant reduction of gIC and CSD spectral power depending on conditions was found in ADHD patients. Reducing power in a wide frequency range in the fronto-central areas is a common phenomenon regardless of whether the eyes were open or closed. Spectral power of local EEG activity isolated by gICA or CSD in the fronto-central areas may be a suitable marker for discrimination of ADHD and healthy adults. Spectral analysis of gIC and CSD provides better sensitivity to discriminate ADHD and healthy adults. Copyright © 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  12. Phenotypic covariance at species' borders.

    PubMed

    Caley, M Julian; Cripps, Edward; Game, Edward T

    2013-05-28

    Understanding the evolution of species limits is important in ecology, evolution, and conservation biology. Despite its likely importance in the evolution of these limits, little is known about phenotypic covariance in geographically marginal populations, and the degree to which it constrains, or facilitates, responses to selection. We investigated phenotypic covariance in morphological traits at species' borders by comparing phenotypic covariance matrices (P), including the degree of shared structure, the distribution of strengths of pair-wise correlations between traits, the degree of morphological integration of traits, and the ranks of matricies, between central and marginal populations of three species-pairs of coral reef fishes. Greater structural differences in P were observed between populations close to range margins and conspecific populations toward range centres, than between pairs of conspecific populations that were both more centrally located within their ranges. Approximately 80% of all pair-wise trait correlations within populations were greater in the north, but these differences were unrelated to the position of the sampled population with respect to the geographic range of the species. Neither the degree of morphological integration, nor ranks of P, indicated greater evolutionary constraint at range edges. Characteristics of P observed here provide no support for constraint contributing to the formation of these species' borders, but may instead reflect structural change in P caused by selection or drift, and their potential to evolve in the future.

  13. 75 FR 25313 - Stillwater Central Railroad, Inc.-Trackage Rights Exemption-Wichita, Tillman and Jackson Railway...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... Railroad, Inc.--Trackage Rights Exemption-- Wichita, Tillman and Jackson Railway Company, Inc., and Hollis & Eastern Railroad Company Pursuant to a written trackage rights agreement (Trackage Agreement) dated January 22, 1992, Wichita, Tillman & Jackson Railway Co. (WTJ) granted approximately 4.6 miles of...

  14. Hazardous Waste Cleanup: TAPI Puerto Rico Incorporated in Guayama, Puerto Rico

    EPA Pesticide Factsheets

    The TAPI facility is located on the southeastern coastal plain of Puerto Rico. The facility is about 1.1 miles north of the Caribbean Sea and 3.5 miles south of the foothills of the Cordillera Central Mountains. The Town of Guayama is located approximately

  15. Soil Exchangeable Phosphorus Pools, Equilibrium Characteristics, and Mass Distribution Coefficients for Eight-Mile Run Watershed, Wisconsin

    DTIC Science & Technology

    2009-09-01

    Galle River Basin, west-central Wisconsin (Figure 1). Livestock ( dairy ) pasture and associated barnyards represent approximately 6 percent of the...Reddy. 1998. Dairy manure influences on phosphorus retention capacity of Spodosols. J. Environ. Qual. 27:522-527. Pierzynski, G. M. 2000. Methods

  16. 33 CFR 110.9 - Wells Harbor, Maine.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 110.9 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.9 Wells Harbor, Maine. (a) Anchorage “A”. All of the... approximately 5,800 sq. yards, encompassing the central portion of Wells Harbor. (b) Anchorage “B”. All of the...

  17. A Policy-Based Approach to Technology Systems

    ERIC Educational Resources Information Center

    Kuhn, Robert M.; Brookes, Kimberly H.; Bellos, Nephellie

    2008-01-01

    Discussions with a central IT organization about integration with existing systems on campus, support costs for the new implementation, and total cost of ownership frequently become adversarial. Simmons College, a small college in Boston with an enrollment of approximately 1,900 undergraduate and 2,800 graduate students, reframed these issues in…

  18. Helping Young Hispanic Learners

    ERIC Educational Resources Information Center

    Garcia, Eugene E.; Jensen, Bryant

    2007-01-01

    Hispanics are the largest and youngest ethnic group in the United States. Moreover, young Hispanic children make up approximately 80 percent of the U.S. English language learner population. They are a heterogeneous group, born both inside and outside the United States and having origins in Mexico, Cuba, Central America, South America, and the…

  19. Phenological changes in nutritive value of honey mesquite leaves, pods and flowers

    USDA-ARS?s Scientific Manuscript database

    The objective of this study was to examine changes in potential forage value of honey mesquite (Prosopis glandulosa) throughout the year. During 2012, samples were obtained at approximately 2 week intervals from April to December in south-central New Mexico. Crude protein content of leaves decreased...

  20. They Remember the "Lost" People.

    ERIC Educational Resources Information Center

    Klages, Karen

    Estimates of the number of children currently missing in the United States are only approximate because there is no effective central data bank to collect information on missing persons and unidentified bodies. However, the problem appears to have reached epidemic proportions. Some parents of missing persons have formed organizations in different…

  1. Serving Distant Learners through Instructional Technologies.

    ERIC Educational Resources Information Center

    Drea, John T.; Armistead, L. Pendleton

    John Wood Community College (JWCC) serves a district population of approximately 90,000 in a predominantly rural section of west-central Illinois. In an effort to address the needs of the rural long-distance learner, JWCC has implemented a variety of instructional delivery techniques. Since its inception, JWCC has contracted with other area…

  2. 76 FR 18165 - Advisory Committee on Earthquake Hazards Reduction Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... from remote locations by calling into a central phone number. DATES: The ACEHR will hold a meeting via... phone number is (301) 975-5640. SUPPLEMENTARY INFORMATION: The Committee was established in accordance... Harman's e-mail address is [email protected] , and her phone number is 301-975-5324. Approximately...

  3. Teaching "With" and "About" Nature of Science, and Science Teacher Knowledge Domains

    ERIC Educational Resources Information Center

    Abd-El-Khalick, Fouad

    2013-01-01

    The ubiquitous goals of helping precollege students develop informed conceptions of nature of science (NOS) and experience inquiry learning environments that progressively approximate authentic scientific practice have been long-standing and central aims of science education reforms around the globe. However, the realization of these goals…

  4. Analysis of environmental setting, surface-water and groundwater data, and data gaps for the Citizen Potawatomi Nation Tribal Jurisdictional Area, Oklahoma, through 2011

    USGS Publications Warehouse

    Andrews, William J.; Harich, Christopher R.; Smith, S. Jerrod; Lewis, Jason M.; Shivers, Molly J.; Seger, Christian H.; Becker, Carol J.

    2013-01-01

    The Citizen Potawatomi Nation Tribal Jurisdictional Area, consisting of approximately 960 square miles in parts of three counties in central Oklahoma, has an abundance of water resources, being underlain by three principal aquifers (alluvial/terrace, Central Oklahoma, and Vamoosa-Ada), bordered by two major rivers (North Canadian and Canadian), and has several smaller drainages. The Central Oklahoma aquifer (also referred to as the Garber-Wellington aquifer) underlies approximately 3,000 square miles in central Oklahoma in parts of Cleveland, Logan, Lincoln, Oklahoma, and Pottawatomie Counties and much of the tribal jurisdictional area. Water from these aquifers is used for municipal, industrial, commercial, agricultural, and domestic supplies. The approximately 115,000 people living in this area used an estimated 4.41 million gallons of fresh groundwater, 12.12 million gallons of fresh surface water, and 8.15 million gallons of saline groundwater per day in 2005. Approximately 8.48, 2.65, 2.24, 1.55, 0.83, and 0.81 million gallons per day of that water were used for domestic, livestock, commercial, industrial, crop irrigation, and thermoelectric purposes, respectively. Approximately one-third of the water used in 2005 was saline water produced during petroleum production. Future changes in use of freshwater in this area will be affected primarily by changes in population and agricultural practices. Future changes in saline water use will be affected substantially by changes in petroleum production. Parts of the area periodically are subject to flooding and severe droughts that can limit available water resources, particularly during summers, when water use increases and streamflows substantially decrease. Most of the area is characterized by rural types of land cover such as grassland, pasture/hay fields, and deciduous forest, which may limit negative effects on water quality by human activities because of lesser emissions of man-made chemicals on such areas than in more urbanized areas. Much of the water in the area is of good quality, though some parts of this area have water quality impaired by very hard surface water and groundwater; large chloride concentrations in some smaller streams; relatively large concentrations of nutrients and counts of fecal-indicator bacteria in the North Canadian River; and chloride, iron, manganese, and uranium concentrations that exceed primary or secondary drinking-water standards in water samples collected from small numbers of wells. Substantial amounts of hydrologic and water-quality data have been collected in much of this area, but there are gaps in those data caused by relatively few streamflow-gaging stations, uneven distribution of surface-water quality sampling sites, lack of surface-water quality sampling at high-flow and low-flow conditions, and lack of a regularly measured and sampled groundwater network. This report summarizes existing water-use, climatic, geographic, hydrologic, and water-quality data and describes several means of filling gaps in hydrologic data for this area.

  5. WFPC2 Observations of the URSA Minor Dwarf Spheroidal Galaxy

    NASA Technical Reports Server (NTRS)

    Mighell, Kenneth J.; Burke, Christopher J.

    1999-01-01

    We present our analysis of archival Hubble Space Telescope Wide Field Planetary Camera 2 (WFPC2) observations in F555W (approximately V) and F814W (approximately I) of the central region of the Ursa Minor dwarf spheroidal galaxy. The V versus V - I color-magnitude diagram features a sparsely populated blue horizontal branch, a steep thin red giant branch, and a narrow subgiant branch. The main sequence reaches approximately 2 magnitudes below the main-sequence turnoff (V(sup UMi, sub TO) approximately equals 23.27 +/- 0.11 mag) of the median stellar population. We compare the fiducial sequence of the Galactic globular cluster M92 (NGC 6341). The excellent match between Ursa Minor and M92 confirms that the median stellar population of the UMi dSph galaxy is metal poor ([Fe/H](sub UMi) approximately equals [Fe/H](sub M92) approximately equals -2.2 dex) and ancient (age(sub UMi)approximately equalsage(sub M92) approximately equals 14 Gyr). The B - V reddening and the absorption in V are estimated to be E(B - V) = 0.03 +/- 0.01 mag and A(sup UMi, sub V) = 0.09 +/- 0.03 mag. A new estimate of the distance modulus of Ursa Minor, (m - M)(sup UMi, sub 0) = 19.18 +/- 0.12 mag, has been derived based on fiducial-sequence fitting M92 [DELTA.V(sub UMi - M92) = 4.60 +/- 0.03 mag and DELTA(V - I)(sub UMi - M92) = 0.010 +/- 0.005 mag] and the adoption of the apparent V distance modulus for M92 of (m - M)(sup M92, sub V) = 14.67 +/- 0.08 mag (Pont et al. 1998, A&A, 329, 87). The Ursa Minor dwarf spheroidal galaxy is then at a distance of 69 +/- 4 kpc from the Sun. These HST observations indicate that Ursa Minor has had a very simple star formation history consisting mainly of a single major burst of star formation about 14 Gyr ago which lasted approximately < 2 Gyr. While we may have missed minor younger stellar populations due to the small field-of-view of the WFPC2 instrument, these observations clearly show that most of the stars in the central region Ursa Minor dwarf spheroidal galaxy are ancient. If the ancient Galactic globular clusters, like M92, formed concurrently with the early formation of the Milky Way galaxy itself, then the Ursa Minor dwarf spheroidal is probably as old as the Milky Way.

  6. A Weighted Measurement Fusion Particle Filter for Nonlinear Multisensory Systems Based on Gauss–Hermite Approximation

    PubMed Central

    Li, Yun

    2017-01-01

    We addressed the fusion estimation problem for nonlinear multisensory systems. Based on the Gauss–Hermite approximation and weighted least square criterion, an augmented high-dimension measurement from all sensors was compressed into a lower dimension. By combining the low-dimension measurement function with the particle filter (PF), a weighted measurement fusion PF (WMF-PF) is presented. The accuracy of WMF-PF appears good and has a lower computational cost when compared to centralized fusion PF (CF-PF). An example is given to show the effectiveness of the proposed algorithms. PMID:28956862

  7. Direct spectroscopic evidence for ionized polycyclic aromatic hydrocarbons in the interstellar medium.

    PubMed

    Sloan, G C; Hayward, T L; Allamandola, L J; Bregman, J D; DeVito, B; Hudgins, D M

    1999-03-01

    Long-slit 8-13 micrometers spectroscopy of the nebula around NGC 1333 SVS 3 reveals spatial variations in the strength and shape of emission features that are probably produced by polycyclic aromatic hydrocarbons (PAHs). Close to SVS 3, the 11.2 micrometers feature develops an excess at approximately 10.8-11.0 micrometers and a feature appears at approximately 10 micrometers. These features disappear with increasing distance from the central source, and they show striking similarities to recent laboratory data of PAH cations, providing the first identification of emission features arising specifically from ionized PAHs in the interstellar medium.

  8. The ESR signals in silk fibroin and wool keratin under both the effect of UV-irradiation and without any external effects and the formation of free radicals.

    PubMed

    Mamedov, Sh V; Aktas, B; Cantürk, M; Aksakal, B; Alekperov, V; Bülbül, F; Yilgin, R; Aslanov, R B

    2002-08-01

    ESR studies have been done on natural and UV-irradiated silk fibroins and wool keratins at the temperature range of -196 degrees C to 20 C. The intensities of ESR signals obtained from the irradiated samples at -196 C remarkably increase with respect to those of natural samples. While the signals mainly consist of triplet peaks at -196 C. a doublet arises around the room temperatures. For the first time, at room temperature without any external effect the complicated ESR spectra of fibrous proteins (wool keratin and silk fibroin) whose components are as follows have been observed: (1) (for white wool keratin) a central doublet with deltaHm = 1.1 mT and g = 2.0075; deltaHm = 5mT and g = 2.1911; (2) a wide peak with deltaHm approximately 66 mT and g approximately 2.1575; (3) the 'sulfur' peak given in the literature with deltaHm = 2.2 mT and g = 2.0218; (4) the signal with deltaHm = 0.6 mT and g = 2.0065, and for silk fibroin, (a) a very wide signal with deltaHm approximately 70 mT and g approximately 2.084; (b) a very sharp signal with deltaHm approximately 1.1 mT and g approximately 2.01; and (c) relatively narrower signal with deltaHm approximately 5 mT and g approximately 2.336. It has been shown by recombination kinetic method that 30-50% of the free radicals formed by UV-irradiation do not undergo recombination up to 220 degrees C and 15 degrees C for silk libroin and wool keratin, respectively, even they keep their concentration constant for long period of time (weeks, months, even longer). In this article, considering above-mentioned results, the mechanism of signals observed in natural wool keratin and silk fibroin without any external effects is examined. We can briefly explain the role of the subject of the article, by considering fibrous proteins and some applications of the reactions by free radical occurring in these proteins tinder the effects of different factors in medicine and biology and the important role of oxidation and the other kinds of degradations on these processes. as well as the significant applications of ESR investigations on comprehending the processes by free radical.

  9. Sediment Deposition, Erosion, and Bathymetric Change in Central San Francisco Bay: 1855-1979

    USGS Publications Warehouse

    Fregoso, Theresa A.; Foxgrover, Amy C.; Jaffe, Bruce E.

    2008-01-01

    Central San Francisco Bay is the hub of a dynamic estuarine system connecting the San Joaquin and Sacramento River Deltas, Suisun Bay, and San Pablo Bay to the Pacific Ocean and South San Francisco Bay. To understand the role that Central San Francisco Bay plays in sediment transport throughout the system, it is necessary to first determine historical changes in patterns of sediment deposition and erosion from both natural and anthropogenic forces. The first extensive hydrographic survey of Central San Francisco Bay was conducted in 1853 by the National Ocean Service (NOS) (formerly the United States Coast and Geodetic Survey (USCGS)). From 1894 to 1979, four additional surveys, composed of a total of approximately 700,000 bathymetric soundings, were collected within Central San Francisco Bay. Converting these soundings into accurate bathymetric models involved many steps. The soundings were either hand digitized directly from the original USCGS and NOS hydrographic sheets (H-sheets) or obtained digitally from the National Geophysical Data Center's (NGDC) Geophysical Data System (GEODAS) (National Geophysical Data Center, 1996). Soundings were supplemented with contours that were either taken directly from the H-sheets or added in by hand. Shorelines and marsh areas were obtained from topographic sheets. The digitized soundings, depth contours, shorelines, and marsh areas were entered into a geographic information system (GIS) and georeferenced to a common horizontal datum. Using surface modeling software, bathymetric grids with a horizontal resolution of 25 m were developed for each of the five hydrographic surveys. Before analyses of sediment deposition and erosion were conducted, interpolation bias was removed and all of the grids were converted to a common vertical datum. These bathymetric grids were then used to develop bathymetric change maps for subsequent survey periods and to determine long-term changes in deposition and erosion by calculating volumes and rates of net sediment change. Central San Francisco Bay experienced periods of both deposition and erosion, but overall experienced a net gain in sediment from 1855 to 1979 of approximately 42x106 m3 (0.33x106 m3 / yr). Over this same time period, 92 percent of the tidal marsh and 69 percent of the intertidal mudflats were lost as human activity increased and the shorefront was developed. During the first time period, from 1855 to 1895, Central San Francisco Bay was erosional, losing roughly 2x106 m3 / yr of sediment. The next time period was depositional, with a net gain of approximately 3x106 m3 / yr of sediment from 1895 to 1947. The last time period, from 1947 to 1979, was erosional again, losing roughly 2x106 m3 / yr of sediment. Sedimentation patterns also varied spatially. The northern part of Central San Francisco Bay was depositional during all change periods while the eastern region alternated between erosional and depositional. Central San Francisco Bay sedimentation patterns have also been strongly impacted by anthropogenic activities, such as dredging and dredge disposal, borrow pits, and sand mining. For example, bathymetric change at a borrow pit created near Bay Farm Island sometime between the 1947 and 1979 surveys indicates roughly 25x106 m3 of sediment was removed from the system.

  10. Geologic Map of the Nulato Quadrangle, West-Central Alaska

    USGS Publications Warehouse

    Patton, W.W.; Moll-Stalcup, E. J.

    2000-01-01

    Introduction The Nulato quadrangle encompasses approximately 17,000 km2 (6,500 mi2) of west-central Alaska within the Yukon River drainage basin. The quadrangle straddles two major geologic features-the Yukon-Koyukuk sedimentary basin, a huge triangle-shaped Cretaceous depression that stretches across western Alaska from the Brooks Range to the Yukon delta; and the Ruby geanticline,a broad uplift of pre-Cretaceous rocks that borders the Yukon-Koyukuk basin on the southeast. The Kaltag Fault crosses the quadrangle diagonally from northeast to southwest and dextrally offsets all major geologic features as much as 130 km.

  11. Groundwater quality in the shallow aquifers of the Monterey Bay, Salinas Valley, and adjacent highland areas, Southern Coast Ranges, California

    USGS Publications Warehouse

    Burton, Carmen

    2018-05-30

    The Monterey-Salinas Shallow Aquifer study unit covers approximately 7,820 square kilometers (km2) in Santa Cruz, Monterey, and San Luis Obispo Counties in the Central Coast Hydrologic Region of California. The study unit was divided into four study areas—Santa Cruz, Pajaro Valley, Salinas Valley, and Highlands. More than 75 percent of the water used for drinking-water supply in the Central Coast Hydrologic Region of California is groundwater, and there are more than 8,000 well driller’s logs for domestic wells (California Department of Water Resources, 2013).

  12. Storm-related mortality--central Texas, October 17-31, 1998.

    PubMed

    2000-02-25

    On October 17, 1998, a series of storms moved across the central and south regions of Texas, dropping up to 22 inches of rain in some areas and spawning several tornados. Sixty Texas counties (24%) reported flooding during October 17-19. Thirty-six counties became eligible for federal and/or state assistance as a result of damages suffered from this storm system during October 17-31. Estimated flood damage was approximately $900 million, including damage to 12,000 homes, 700 businesses, and public property. This report summarizes findings of an epidemiologic investigation of 31 deaths associated with the storm system.

  13. Groundwater Quality in the Shallow Aquifers of the Monterey Bay, Salinas Valley, and Adjacent Highland Areas, Southern Coast Ranges, California

    USGS Publications Warehouse

    Burton, Carmen

    2018-05-30

    The Monterey-Salinas Shallow Aquifer study unit covers approximately 7,820 square kilometers (km2) in Santa Cruz, Monterey, and San Luis Obispo Counties in the Central Coast Hydrologic Region of California. The study unit was divided into four study areas—Santa Cruz, Pajaro Valley, Salinas Valley, and Highlands. More than 75 percent of the water used for drinking-water supply in the Central Coast Hydrologic Region of California is groundwater, and there are more than 8,000 well driller’s logs for domestic wells (California Department of Water Resources, 2013).

  14. ASCA observation of NGC 4636: Dark matter and metallicity gradient

    NASA Technical Reports Server (NTRS)

    Mushotzky, R. F.; Loewenstein, M.; Awaki, H.; Makishima, K.; Matsushita, K.; Matsumoto, H.

    1994-01-01

    We present our analysis of ASCA PV phase observation of the elliptical galaxy NGC 4636. Solid state imaging spectrometer (SIS) spectra in six concentric annuli centered on NGC 4636 are used to derive temperature, metallicity, and column density profiles for the hot interstellar medium. Outside of the central 3 min the temperature is roughly constant at approximately 0.85 keV, while the metallicity decreases from greater than 0.36 solar at the center to less than 0.12 solar at R approximately 9 min. The implications of this gradient for elliptical galaxy formation and the enrichment of intracluster gas are discussed. We derive a detailed mass profile consistent with the stellar velocity dispersion and with ROSAT position sensitive proportional counter (PSPC) and ASCA SIS X-ray temperature profiles. We find that NGC 4636 becomes dark matter dominated at roughly the de Vaucouleurs radius, and, at r approximately 100 kpc, the ratio of dark to luminous matter density is approximately 80 and solar mass/solar luminosity approximately equal to 150. Evidence for the presence of a cooling flow is also discussed.

  15. Exploiting the dynamics of S-phase tracers in developing brain: interkinetic nuclear migration for cells entering versus leaving the S-phase

    NASA Technical Reports Server (NTRS)

    Hayes, N. L.; Nowakowski, R. S.

    2000-01-01

    Two S-phase markers for in vivo studies of cell proliferation in the developing central nervous system, tritiated thymidine ((3)H-TdR) and bromodeoxyuridine (BUdR), were compared using double-labeling techniques in the developing mouse cortex at embryonic day 14 (E14). The labeling efficiencies and detectability of the two tracers were approximately equivalent, and there was no evidence of significant tracer interactions that depend on order of administration. For both tracers, the loading time needed to label an S-phase cell to detectability is estimated at <0.2 h shortly after the injection of the label, but, as the concentration of the label falls, it increases to approximately 0.65 h after about 30 min. Thereafter, cells that enter the S-phase continue to become detectably labeled for approximately 5-6 h. The approximate equivalence of these two tracers was exploited to observe directly the numbers and positions of nuclei entering (labeled with the second tracer only) and leaving (labeled with the first tracer only) the S-phase. As expected, the numbers of nuclei entering and leaving the S-phase both increased as the interval between the two injections lengthened. Also, nuclei leaving the S-phase rapidly move towards the ventricular surface during G2, but, unexpectedly, the distribution of the entering nuclei does not differ significantly from the distribution of the nuclei in the S-phase. This indicates that: (1) the extent and rate of abventricular nuclear movement during G1 is variable, such that not all nuclei traverse the entire width of the ventricular zone, and (2) interkinetic nuclear movements are minimal during S-phase. Copyright 2000 S. Karger AG, Basel.

  16. 2 Micron Spectroscopy within 0&farcs;3 of Sagittarius A*

    PubMed

    Figer; Becklin; McLean; Gilbert; Graham; Larkin; Levenson; Teplitz; Wilcox; Morris

    2000-04-10

    We present moderate- (R approximately 2700) and high-resolution (R approximately 22,400) 2.0-2.4 µm spectroscopy of the central 0.1 arcsec2 of the Galaxy obtained with the facility near-infrared spectrometer (NIRSPEC) for the Keck II telescope. The composite spectra do not have any features attributable to the brightest stars in the central cluster; i.e., after background subtraction, W12CO&parl0;2-0&parr0;<2 Å. This stringent limit leads us to conclude that the majority, if not all, of the stars are hotter than typical red giants. Coupled with previously reported photometry, we conclude that the sources are likely OB main-sequence stars. In addition, the continuum slope in the composite spectrum is bluer than that of a red giant and is similar to that of the nearby hot star IRS 16NW. It is unlikely that they are late-type giants stripped of their outer envelopes because such sources would be much fainter than those observed. Given their inferred youth (tauage<20 Myr), we suggest the possibility that the stars have formed within 0.1 pc of the supermassive black hole. We find a newly identified broad-line component (VFWHM approximately 1000 km s-1) toward the 2.2178 µm [Fe iii] line located within a few arcseconds of Sagittarius A*. A similar component is not seen in the Brgamma emission.

  17. Mixed models and reduction method for dynamic analysis of anisotropic shells

    NASA Technical Reports Server (NTRS)

    Noor, A. K.; Peters, J. M.

    1985-01-01

    A time-domain computational procedure is presented for predicting the dynamic response of laminated anisotropic shells. The two key elements of the procedure are: (1) use of mixed finite element models having independent interpolation (shape) functions for stress resultants and generalized displacements for the spatial discretization of the shell, with the stress resultants allowed to be discontinuous at interelement boundaries; and (2) use of a dynamic reduction method, with the global approximation vectors consisting of the static solution and an orthogonal set of Lanczos vectors. The dynamic reduction is accomplished by means of successive application of the finite element method and the classical Rayleigh-Ritz technique. The finite element method is first used to generate the global approximation vectors. Then the Rayleigh-Ritz technique is used to generate a reduced system of ordinary differential equations in the amplitudes of these modes. The temporal integration of the reduced differential equations is performed by using an explicit half-station central difference scheme (Leap-frog method). The effectiveness of the proposed procedure is demonstrated by means of a numerical example and its advantages over reduction methods used with the displacement formulation are discussed.

  18. A seismological overview of the induced earthquakes in the Duvernay play near Fox Creek, Alberta

    NASA Astrophysics Data System (ADS)

    Schultz, Ryan; Wang, Ruijia; Gu, Yu Jeffrey; Haug, Kristine; Atkinson, Gail

    2017-01-01

    This paper summarizes the current state of understanding regarding the induced seismicity in connection with hydraulic fracturing operations targeting the Duvernay Formation in central Alberta, near the town of Fox Creek. We demonstrate that earthquakes in this region cluster into distinct sequences in time, space, and focal mechanism using (i) cross-correlation detection methods to delineate transient temporal relationships, (ii) double-difference relocations to confirm spatial clustering, and (iii) moment tensor solutions to assess fault motion consistency. The spatiotemporal clustering of the earthquake sequences is strongly related to the nearby hydraulic fracturing operations. In addition, we identify a preference for strike-slip motions on subvertical faults with an approximate 45° P axis orientation, consistent with expectation from the ambient stress field. The hypocentral geometries for two of the largest-magnitude (M 4) sequences that are robustly constrained by local array data provide compelling evidence for planar features starting at Duvernay Formation depths and extending into the shallow Precambrian basement. We interpret these lineaments as subvertical faults orientated approximately north-south, consistent with the regional moment tensor solutions. Finally, we conclude that the sequences were triggered by pore pressure increases in response to hydraulic fracturing stimulations along previously existing faults.

  19. Synaptic excitation mediated by AMPA receptors in rat cerebellar slices is selectively enhanced by aniracetam and cyclothiazide.

    PubMed

    Boxall, A R; Garthwaite, J

    1995-05-01

    AMPA receptors mediate fast, glutamatergic synaptic transmission in the central nervous system. The time-course of the associated postsynaptic current has been suggested to be determined principally by the kinetics of glutamate binding and receptor desensitization. Aniracetam and cyclothiazide are drugs capable of selectively preventing desensitization of the AMPA receptor. To investigate the relevance of desensitization to fast synaptic transmission in the cerebellum we have tested these compounds against AMPA-induced depolarizations and postsynaptic potentials using the grease-gap recording technique. Aniracetam (1 microM-5 mM) and cyclothiazide (1 microM-500 microM) both enhanced the depolarising action of AMPA (1 microM) on Purkinje cells in a concentration-dependent manner. At the highest concentrations tested, the increases over controls were approximately 600% and 800% respectively. Aniracetam also increased, in a concentration-dependent manner, the amplitude of the evoked synaptic potentials of both parallel fibre-Purkinje cell and mossy fibre-granule cell pathways, with the highest concentrations tested enhancing the potentials by approximately 60% and 75% respectively. These data suggest that, at two different synapses in the cerebellum, AMPA receptor desensitization occurs physiologically and is likely to contribute to the shape of fast synaptic currents.

  20. A clinical trial to evaluate the effects of flumethrin or ivermectin treatment on hemoparasites, gastrointestinal parasites, conception and daily weight gain in a dairy farm in Japan.

    PubMed

    Yamane, I; Arai, S; Nakamura, Y; Hisashi, M; Fukazawa, Y; Onuki, T

    2000-02-01

    A clinical trial was performed to compare the effects of flumethrin and ivermectin treatments of grazing heifers at one farm in central Japan. 64 heifers were randomly allocated into two groups. Flumethrin (1 mg/kg pour on) was applied approximately once every 3 weeks to heifers in one group and heifers in the second group were injected approximately once every month with ivermectin (200 microg/kg; id). Between groups, no significant differences were detected in the proportions of animals that showed parasitemia of Theileria sergenti and conception risks. Significantly lower average log-transformed nematode-egg counts and higher average daily weight gain were observed in the ivermectin-treated group. Animals with higher body weight at the start of grazing and lower log-transformed total nematode-egg and coccidia-oocyst counts had higher odds of conceiving. Animals with ivermectin treatment, lower body weight at the start of grazing and lower log-transformed coccidia-oocyst count had higher daily weight gain. Ivermectin may be more useful in this farm because of the higher productivity for cattle and lower cost for its usage.

  1. Multiple cooling episodes in the Central Tarim (Northwest China) revealed by apatite fission track analysis and vitrinite reflectance data

    NASA Astrophysics Data System (ADS)

    Chang, Jian; Qiu, Nansheng; Song, Xinying; Li, Huili

    2016-06-01

    Apatite fission track and vitrinite reflectance are integrated for the first time to study the cooling history in the Central Tarim, northwest China. The paleo-temperature profiles from vitrinite reflectance data of the Z1 and Z11 wells showed a linear relationship with depth, suggesting an approximately 24.8 °C/km paleo-geothermal gradient and 2700-3900 m of erosion during the Early Mesozoic. The measured apatite fission track ages from well Z2 in the Central Tarim range from 39 to 159 Ma and effectively record the Meso-Cenozoic cooling events that occurred in Central Tarim. Moreover, two cooling events at 190-140 Ma in the Early Jurassic-Early Cretaceous and 80-45 Ma in the Late Cretaceous-Paleocene revealed by measured AFT data and thermal modeling results are related to the collisions of the Qiangtang-Lhasa terranes and the Greater India Plate with the southern margin of the Eurasian Plate, respectively. This study provides new insights into the tectonic evolution of the Tarim Basin (and more broadly Central Asia) and for hydrocarbon generation and exploration in the Central Tarim.

  2. Numerical simulation of groundwater flow, resource optimization, and potential effects of prolonged drought for the Citizen Potawatomi Nation Tribal Jurisdictional Area, central Oklahoma

    USGS Publications Warehouse

    Ryter, Derek W.; Kunkel, Christopher D.; Peterson, Steven M.; Traylor, Jonathan P.

    2015-08-13

    The hypothetical decrease in recharge during the simulated drought caused groundwater in storage over the entire model in the study area to decrease by 361,500 acre-feet (14,100 acre-feet in the North Canadian River alluvial aquifer and 347,400 acre-feet in the Central Oklahoma aquifer), or approximately 0.2 percent of the total groundwater in storage over the drought period. This small percentage of groundwater loss showed that the Central Oklahoma aquifer as a bedrock aquifer has relatively low rates of recharge from the surface relative to the approximate storage. The budget for base flow to the North Canadian River indicated that the change in groundwater flow to the North Canadian River decreased during the 10-year drought by 386,500 acre-feet, or 37 percent. In all other parts of the Citizen Potawatomi Nation Tribal Jurisdictional Area, base flow decreased by 292,000 acre-feet, or 28 percent. Streamflow in the North Canadian River at the streamflow-gaging station at Shawnee, Okla., decreased during the hypothetical drought by as much as 28 percent, and the mean change in streamflow decreased as much as 16 percent. Streamflow at the Shawnee streamflow-gaging station did not recover to nondrought conditions until about 3 years after the simulated drought ended, during the relatively wet year of 2007.

  3. ARM - Midlatitude Continental Convective Clouds (jensen-sonde)

    DOE Data Explorer

    Jensen, Mike; Comstock, Jennifer; Genio, Anthony Del; Giangrande, Scott; Kollias, Pavlos

    2012-01-19

    A major component of the Mid-latitude Continental Convective Clouds Experiment (MC3E) field campaign was the deployment of an enhanced radiosonde array designed to capture the vertical profile of atmospheric state variables (pressure, temperature, humidity wind speed and wind direction) for the purpose of deriving the large-scale forcing for use in modeling studies. The radiosonde array included six sites (enhanced Central Facility [CF-1] plus five new sites) launching radiosondes at 3-6 hour sampling intervals. The network will cover an area of approximately (300)2 km2 with five outer sounding launch sites and one central launch location. The five outer sounding launch sites are: S01 Pratt, KS [ 37.7oN, 98.75oW]; S02 Chanute, KS [37.674, 95.488]; S03 Vici, Oklahoma [36.071, -99.204]; S04 Morris, Oklahoma [35.687, -95.856]; and S05 Purcell, Oklahoma [34.985, -97.522]. Soundings from the SGP Central Facility during MC3E can be retrieved from the regular ARM archive. During routine MC3E operations 4 radiosondes were launched from each of these sites (approx. 0130, 0730, 1330 and 1930 UTC). On days that were forecast to be convective up to four additional launches were launched at each site (approx. 0430, 1030, 1630, 2230 UTC). There were a total of approximately 14 of these high frequency launch days over the course of the experiment.

  4. Radio and near-infrared images of IRAS 21282+5050: A transitional planetary nebula

    NASA Astrophysics Data System (ADS)

    Likkel, L.; Morris, M.; Kastner, J. H.; Forveille, T.

    1994-02-01

    We present 2 and 6 cm Very Large Array (VLA) images of the young planetary nebula IRAS 21282+5050. The nebular dimensions at 2 and 6 cm are about 4 sec x 3 sec, and the total flux density is almost 7 mJy at each wavelength, suggesting a spectral index of approximately 0. The emission is not centrally peaked and appears to arise in a shell or torus. The relatively low flux for the angular size and assumed distance implies an average electron density of 2000-10000/cu cm, low for compact planetary nebulae. An image and a polarization map of IRAS 21282+5050 at 2.2 microns are also presented. At 2.2 microns (K-band), the nebula has a diameter of approximately 6 sec. The image is centrally peaked, in large part because the central star contributes significantly to the K magnitude of 9.46 (104 mJy). The 2.2 micron polarization map does not display a centrosymmetric pattern characteristic of scattering; within a 7 sec aperture, we find an upper limit of 1.1% for the polarization. These results indicate that there is not a large component of scattered light in the near-infrared. IRAS 21282+5050 has significantly more emission at 2 microns than is expected for free-free and free-bound emission, however. We suggest that this emission may arise from transiently heated dust.

  5. Quetzal: a transposon of the Tc1 family in the mosquito Anopheles albimanus.

    PubMed

    Ke, Z; Grossman, G L; Cornel, A J; Collins, F H

    1996-10-01

    A member of the Tc1 family of transposable elements has been identified in the Central and South American mosquito Anopheles albimanus. The full-length Quetzal element is 1680 base pairs (bp) in length, possesses 236 bp inverted terminal repeats (ITRs), and has a single open reading frame (ORF) with the potential of encoding a 341-amino-acid (aa) protein that is similar to the transposases of other members of the Tc1 family, particularly elements described from three different Drosophila species. The approximately 10-12 copies per genome of Quetzal are found in the euchromatin of all three chromosomes of A. albimanus. One full-length clone, Que27, appears capable of encoding a complete transposase and may represent a functional copy of this element.

  6. Universal recovery map for approximate Markov chains.

    PubMed

    Sutter, David; Fawzi, Omar; Renner, Renato

    2016-02-01

    A central question in quantum information theory is to determine how well lost information can be reconstructed. Crucially, the corresponding recovery operation should perform well without knowing the information to be reconstructed. In this work, we show that the quantum conditional mutual information measures the performance of such recovery operations. More precisely, we prove that the conditional mutual information I ( A : C | B ) of a tripartite quantum state ρ ABC can be bounded from below by its distance to the closest recovered state [Formula: see text], where the C -part is reconstructed from the B -part only and the recovery map [Formula: see text] merely depends on ρ BC . One particular application of this result implies the equivalence between two different approaches to define topological order in quantum systems.

  7. Comparative transcriptome analysis reveals vertebrate phylotypic period during organogenesis

    PubMed Central

    Irie, Naoki; Kuratani, Shigeru

    2011-01-01

    One of the central issues in evolutionary developmental biology is how we can formulate the relationships between evolutionary and developmental processes. Two major models have been proposed: the 'funnel-like' model, in which the earliest embryo shows the most conserved morphological pattern, followed by diversifying later stages, and the 'hourglass' model, in which constraints are imposed to conserve organogenesis stages, which is called the phylotypic period. Here we perform a quantitative comparative transcriptome analysis of several model vertebrate embryos and show that the pharyngula stage is most conserved, whereas earlier and later stages are rather divergent. These results allow us to predict approximate developmental timetables between different species, and indicate that pharyngula embryos have the most conserved gene expression profiles, which may be the source of the basic body plan of vertebrates. PMID:21427719

  8. Universal recovery map for approximate Markov chains

    PubMed Central

    Sutter, David; Fawzi, Omar; Renner, Renato

    2016-01-01

    A central question in quantum information theory is to determine how well lost information can be reconstructed. Crucially, the corresponding recovery operation should perform well without knowing the information to be reconstructed. In this work, we show that the quantum conditional mutual information measures the performance of such recovery operations. More precisely, we prove that the conditional mutual information I(A:C|B) of a tripartite quantum state ρABC can be bounded from below by its distance to the closest recovered state RB→BC(ρAB), where the C-part is reconstructed from the B-part only and the recovery map RB→BC merely depends on ρBC. One particular application of this result implies the equivalence between two different approaches to define topological order in quantum systems. PMID:27118889

  9. Cellular RNA-dependent RNA polymerase involved in posttranscriptional gene silencing has two distinct activity modes.

    PubMed

    Makeyev, Eugene V; Bamford, Dennis H

    2002-12-01

    Recent genetic data suggest that proteins homologous to a plant RNA-dependent RNA polymerase (RdRP) play a central role in posttranscriptional gene silencing (PTGS) in many organisms. We show here that purified recombinant protein QDE-1, a genetic component of PTGS ("quelling") in the fungus Neurospora crassa, possesses RNA polymerase activity in vitro. The full-length enzyme and its enzymatically active C-terminal fragment perform two different reactions on single-stranded RNA templates, synthesizing either extensive RNA chains that form template-length duplexes or approximately 9-21-mer complementary RNA oligonucleotides scattered along the entire template. QDE-1 supports both de novo and primer-dependent initiation mechanisms. These results suggest that several distinct activities of cell-encoded RdRPs can be employed for efficient PTGS in vivo.

  10. Collapse and Fragmentation of Molecular Cloud Cores. VII. Magnetic Fields and Multiple Protostar Formation

    NASA Astrophysics Data System (ADS)

    Boss, Alan P.

    2002-04-01

    Recent observations of star-forming regions suggest that binary and multiple young stars are the rule rather than the exception and implicate fragmentation as the likely mechanism for their formation. Most numerical hydrodynamic calculations of fragmentation have neglected the possibly deleterious effects of magnetic fields, despite ample evidence for the importance of magnetic support of precollapse clouds. We present here the first numerical hydrodynamic survey of the collapse and fragmentation of initially magnetically supported clouds that takes into account several magnetic field effects in an approximate manner. The models are calculated with a three-dimensional, finite differences code that solves the equations of hydrodynamics, gravitation, and radiative transfer in the Eddington and diffusion approximations. Magnetic field effects are included through two simple approximations: magnetic pressure is added to the gas pressure, and magnetic tension is approximated by gravity dilution once collapse is well underway. Ambipolar diffusion of the magnetic field leading to cloud collapse is treated approximately as well. Models are calculated for a variety of initial cloud density profiles, shapes, and rotation rates. We find that in spite of the inclusion of magnetic field effects, dense cloud cores are capable of fragmenting into binary and multiple protostar systems. Initially prolate clouds tend to fragment into binary protostars, while initially oblate clouds tend to fragment into multiple protostar systems containing a small number (of the order of 4) of fragments. The latter are likely to be subject to rapid orbital evolution, with close encounters possibly leading to the ejection of fragments. Contrary to expectation, magnetic tension effects appear to enhance fragmentation, allowing lower mass fragments to form than would otherwise be possible, because magnetic tension helps to prevent a central density singularity from forming and producing a dominant single object. Magnetically supported dense cloud cores thus seem to be capable of collapsing and fragmenting into sufficient numbers of binary and multiple protostar systems to be compatible with observations of the relative rarity of single protostars.

  11. The small-x gluon distribution in centrality biased pA and pp collisions

    NASA Astrophysics Data System (ADS)

    Dumitru, Adrian; Kapilevich, Gary; Skokov, Vladimir

    2018-06-01

    The nuclear modification factor RpA (pT) provides information on the small-x gluon distribution of a nucleus at hadron colliders. Several experiments have recently measured the nuclear modification factor not only in minimum bias but also for central pA collisions. In this paper we analyze the bias on the configurations of soft gluon fields introduced by a centrality selection via the number of hard particles. Such bias can be viewed as reweighting of configurations of small-x gluons. We find that the biased nuclear modification factor QpA (pT) for central collisions is above RpA (pT) for minimum bias events, and that it may redevelop a "Cronin peak" even at small x. The magnitude of the peak is predicted to increase approximately like 1 /A⊥ ν, ν ∼ 0.6 ± 0.1, if one is able to select more compact configurations of the projectile proton where its gluons occupy a smaller transverse area A⊥. We predict an enhanced Qpp (pT) - 1 ∼ 1 /(pT2) ν and a Cronin peak even for central pp collisions.

  12. Structure of pseudotachylyte vein systems as a key to co-seismic rupture dynamics: the case of Gavilgarh-Tan Shear Zone, central India

    NASA Astrophysics Data System (ADS)

    Chattopadhyay, A.; Bhattacharjee, D.; Mukherjee, S.

    2014-04-01

    The secondary fractures associated with a major pseudotachylyte-bearing fault vein in the sheared aplitic granitoid of the Proterozoic Gavilgarh-Tan Shear Zone in central India are mapped at the outcrop scale. The fracture maps help to identify at least three different types of co-seismic ruptures, e.g., X-X', T1 and T2, which characterize sinistral-sense shearing of rocks, confined between two sinistral strike-slip faults slipping at seismic rate. From the asymmetric distribution of tensile fractures around the sinistral-sense fault vein, the direction of seismic rupture propagation is predicted to have occurred from west-southwest to east-northeast, during an ancient (Ordovician?) earthquake. Calculations of approximate co-seismic displacement on the faults and seismic moment ( M 0) of the earthquake are attempted, following the methods proposed by earlier workers. These estimates broadly agree to the findings from other studied fault zones (e.g., Gole Larghe Fault zone, Italian Alps). This study supports the proposition by some researchers that important seismological information can be extracted from tectonic pseudotachylytes of all ages, provided they are not reworked by subsequent tectonic activity.

  13. Independent origins of Indian caste and tribal paternal lineages.

    PubMed

    Cordaux, Richard; Aunger, Robert; Bentley, Gillian; Nasidze, Ivane; Sirajuddin, S M; Stoneking, Mark

    2004-02-03

    The origins of the nearly one billion people inhabiting the Indian subcontinent and following the customs of the Hindu caste system are controversial: are they largely derived from Indian local populations (i.e. tribal groups) or from recent immigrants to India? Archaeological and linguistic evidence support the latter hypothesis, whereas recent genetic data seem to favor the former hypothesis. Here, we analyze the most extensive dataset of Indian caste and tribal Y chromosomes to date. We find that caste and tribal groups differ significantly in their haplogroup frequency distributions; caste groups are homogeneous for Y chromosome variation and more closely related to each other and to central Asian groups than to Indian tribal or any other Eurasian groups. We conclude that paternal lineages of Indian caste groups are primarily descended from Indo-European speakers who migrated from central Asia approximately 3,500 years ago. Conversely, paternal lineages of tribal groups are predominantly derived from the original Indian gene pool. We also provide evidence for bidirectional male gene flow between caste and tribal groups. In comparison, caste and tribal groups are homogeneous with respect to mitochondrial DNA variation, which may reflect the sociocultural characteristics of the Indian caste society.

  14. Determination of Stability and Control Derivatives using Computational Fluid Dynamics and Automatic Differentiation

    NASA Technical Reports Server (NTRS)

    Park, Michael A.; Green, Lawrence L.; Montgomery, Raymond C.; Raney, David L.

    1999-01-01

    With the recent interest in novel control effectors there is a need to determine the stability and control derivatives of new aircraft configurations early in the design process. These derivatives are central to most control law design methods and would allow the determination of closed-loop control performance of the vehicle. Early determination of the static and dynamic behavior of an aircraft may permit significant improvement in configuration weight, cost, stealth, and performance through multidisciplinary design. The classical method of determining static stability and control derivatives - constructing and testing wind tunnel models - is expensive and requires a long lead time for the resultant data. Wind tunnel tests are also limited to the preselected control effectors of the model. To overcome these shortcomings, computational fluid dynamics (CFD) solvers are augmented via automatic differentiation, to directly calculate the stability and control derivatives. The CFD forces and moments are differentiated with respect to angle of attack, angle of sideslip, and aircraft shape parameters to form these derivatives. A subset of static stability and control derivatives of a tailless aircraft concept have been computed by two differentiated inviscid CFD codes and verified for accuracy with central finite-difference approximations and favorable comparisons to a simulation database.

  15. High Resolution Observations of Escaping Ions in the Martian Magnetotail

    NASA Astrophysics Data System (ADS)

    Halekas, J. S.; Raman, C.; Brain, D.; DiBraccio, G. A.; Harada, Y.; McFadden, J. P.; Mitchell, D. L.; Connerney, J. E. P.; Jakosky, B. M.

    2016-12-01

    Ions escape from the Martian upper atmosphere via a number of channels, including the central plasmasheet of the magnetotail. Mars Express observations show that the heavy ions O+ and O2+ escaping through the central tail often have approximately the same energy, suggesting acceleration in a quasi-static electric field, which has been interpreted as a Hall electric field. The Solar Wind Ion Analyzer (SWIA) on MAVEN was designed to measure the upstream solar wind. However, during orbit segments with appropriate spacecraft attitude, SWIA can also make high resolution measurements of escaping ions in the tail. During the prime mission, these observations were only returned sporadically, during periods of intense escaping fluxes that fortuitously triggered a mode switch. Now, in the extended mission, we return high resolution observations from SWIA routinely. Some of these high resolution measurements reveal slight differences in both the direction and energy of escaping O+ and O2+ ions, which may help determine the acceleration process(es). We investigate the location and solar wind conditions for which the escaping ions separate in energy and angle and the systematics of their energies and flow vectors, and discuss the implications for ion acceleration and the overall picture of Martian atmospheric escape.

  16. Central corneal thickness measurements in unoperated eyes and eyes after PRK for myopia using Pentacam, Orbscan II, and ultrasonic pachymetry.

    PubMed

    Kim, Sun Woong; Byun, Yeo Jue; Kim, Eung Kweon; Kim, Tae-im

    2007-11-01

    To compare central corneal thickness measurements obtained in unoperated eyes and eyes after myopic photorefractive keratectomy (PRK) using a rotating Scheimpflug camera (Pentacam), a scanning slit corneal topography system (Orbscan II), and ultrasonic pachymetry. Corneal thickness was measured using Pentacam, Orbscan II, and ultrasonic pachymetry in 25 unoperated eyes (unoperated group), 24 eyes 1 to 3 months after myopic PRK (early postoperative PRK group), and 21 eyes 4 months or more after myopic PRK (late postoperative PRK group). In the unoperated group, corneal thickness measurements were similar for all three methods (P=.125). In the early postoperative PRK group, Orbscan measurements were thinner than Pentacam and ultrasonic measurements by a mean of 69.4 microm and 63.4 microm (P<.001 and P=.002, respectively). In the late postoperative PRK group, Orbscan measurements were thinner than Pentacam measurements by a mean of 36.0 microm (P=.017). Pentacam and ultrasonic pachymetry measurements were similar for all three groups with a mean difference of approximately 10 microm. Following myopic PRK, Pentacam was comparable to ultrasonic pachymetry in measuring corneal thickness, whereas Orbscan measurements were thinner.

  17. Microbial diversity in Cenozoic sediments recovered from the Lomonosov Ridge in the Central Arctic basin.

    PubMed

    Forschner, Stephanie R; Sheffer, Roberta; Rowley, David C; Smith, David C

    2009-03-01

    The current understanding of microbes inhabiting deeply buried marine sediments is based largely on samples collected from continental shelves in tropical and temperate latitudes. The geographical range of marine subsurface coring was expanded during the Integrated Ocean Drilling Program Arctic Coring Expedition (IODP ACEX). This expedition to the ice-covered central Arctic Ocean successfully cored the entire 428 m sediment stack on the Lomonosov Ridge during August and September 2004. The recovered cores vary from siliciclastic sediment low in organic carbon (< 0.2%) to organic rich ( approximately 3%) black sediments that rapidly accumulated in the early middle Eocene. Three geochemical environments were characterized based on chemical analyses of porewater: an upper ammonium oxidation zone, a carbonate dissolution zone and a deep (> 200 m below sea floor) sulfate reduction zone. The diversity of microbes within each zone was assessed using 16S rRNA phylogenetic markers. Bacterial 16S rRNA genes were successfully amplified from each of the biogeochemical zones, while archaea was only amplified from the deep sulfate reduction zone. The microbial communities at each zone are phylogenetically different and are most closely related to those from other deep subsurface environments.

  18. Modeling and Simulation of Linear and Nonlinear MEMS Scale Electromagnetic Energy Harvesters for Random Vibration Environments

    PubMed Central

    Sassani, Farrokh

    2014-01-01

    The simulation results for electromagnetic energy harvesters (EMEHs) under broad band stationary Gaussian random excitations indicate the importance of both a high transformation factor and a high mechanical quality factor to achieve favourable mean power, mean square load voltage, and output spectral density. The optimum load is different for random vibrations and for sinusoidal vibration. Reducing the total damping ratio under band-limited random excitation yields a higher mean square load voltage. Reduced bandwidth resulting from decreased mechanical damping can be compensated by increasing the electrical damping (transformation factor) leading to a higher mean square load voltage and power. Nonlinear EMEHs with a Duffing spring and with linear plus cubic damping are modeled using the method of statistical linearization. These nonlinear EMEHs exhibit approximately linear behaviour under low levels of broadband stationary Gaussian random vibration; however, at higher levels of such excitation the central (resonant) frequency of the spectral density of the output voltage shifts due to the increased nonlinear stiffness and the bandwidth broadens slightly. Nonlinear EMEHs exhibit lower maximum output voltage and central frequency of the spectral density with nonlinear damping compared to linear damping. Stronger nonlinear damping yields broader bandwidths at stable resonant frequency. PMID:24605063

  19. An algorithm to estimate PBL heights from wind profiler data

    NASA Astrophysics Data System (ADS)

    Molod, A.; Salmun, H.

    2016-12-01

    An algorithm was developed to estimate planetary boundary layer (PBL) heights from hourlyarchived wind profiler data from the NOAA Profiler Network (NPN) sites located throughoutthe central United States from the period 1992-2012. The long period of record allows ananalysis of climatological mean PBL heights as well as some estimates of year to yearvariability. Under clear conditions, summertime averaged hourly time series of PBL heightscompare well with Richardson-number based estimates at the few NPN stations with hourlytemperature measurements. Comparisons with clear sky MERRA estimates show that the windprofiler (WP) and the Richardson number based PBL heights are lower by approximately 250-500 m.The geographical distribution of daily maximum WP PBL heights corresponds well with theexpected distribution based on patterns of surface temperature and soil moisture. Windprofiler PBL heights were also estimated under mostly cloudy conditions, but the WP estimatesshow a smaller clear-cloudy condition difference than either of the other two PBL height estimates.The algorithm presented here is shown to provide a reliable summer, fall and springclimatology of daytime hourly PBL heights throughout the central United States. The reliabilityof the algorithm has prompted its use to obtain hourly PBL heights from other archived windprofiler data located throughout the world.

  20. Statistical inference on genetic data reveals the complex demographic history of human populations in central Asia.

    PubMed

    Palstra, Friso P; Heyer, Evelyne; Austerlitz, Frédéric

    2015-06-01

    The demographic history of modern humans constitutes a combination of expansions, colonizations, contractions, and remigrations. The advent of large scale genetic data combined with statistically refined methods facilitates inference of this complex history. Here we study the demographic history of two genetically admixed ethnic groups in Central Asia, an area characterized by high levels of genetic diversity and a history of recurrent immigration. Using Approximate Bayesian Computation, we infer that the timing of admixture markedly differs between the two groups. Admixture in the traditionally agricultural Tajiks could be dated back to the onset of the Neolithic transition in the region, whereas admixture in Kyrgyz is more recent, and may have involved the westward movement of Turkic peoples. These results are confirmed by a coalescent method that fits an isolation-with-migration model to the genetic data, with both Central Asian groups having received gene flow from the extremities of Eurasia. Interestingly, our analyses also uncover signatures of gene flow from Eastern to Western Eurasia during Paleolithic times. In conclusion, the high genetic diversity currently observed in these two Central Asian peoples most likely reflects the effects of recurrent immigration that likely started before historical times. Conversely, conquests during historical times may have had a relatively limited genetic impact. These results emphasize the need for a better understanding of the genetic consequences of transmission of culture and technological innovations, as well as those of invasions and conquests. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Pituitary adenylate cyclase activating polypeptide and PAC1 receptor signaling increase Homer 1a expression in central and peripheral neurons.

    PubMed

    Girard, Beatrice M; Keller, Emily T; Schutz, Kristin C; May, Victor; Braas, Karen M

    2004-12-15

    Pituitary adenylate cyclase activating polypeptides (PACAP) and PAC1 receptor signaling have diverse roles in central and peripheral nervous system development and function. In recent microarray analyses for PACAP and PAC1 receptor modulation of neuronal transcripts, the mRNA of Homer 1a (H1a), which encodes the noncrosslinking and immediate early gene product isoform of Homer, was identified to be strongly upregulated in superior cervical ganglion (SCG) sympathetic neurons. Given the prominent roles of Homer in synaptogenesis, synaptic protein complex assembly and receptor/channel signaling, we have examined the ability for PACAP to induce H1a expression in sympathetic, cortical and hippocampal neurons to evaluate more comprehensively the roles of PACAP in synaptic function. In both central and peripheral neuronal cultures, PACAP peptides increased transiently H1a transcript levels approximately 3.5- to 6-fold. From real-time quantitative PCR measurements, the temporal patterns of PACAP-mediated H1a mRNA induction among the different neuronal cultures appeared similar although the onset of sympathetic H1a transcript expression appeared protracted. The increase in H1a transcripts was accompanied by increases in H1a protein levels. Comparative studies with VIP and PACAP(6-38) antagonist demonstrated that the PACAP effects reflected PAC1 receptor activation and signaling. The PAC1 receptor isoforms expressed in central and peripheral neurons can engage diverse intracellular second messenger systems, and studies using selective signaling pathway inhibitors demonstrated that the cyclic AMP/PKA and MEK/ERK cascades are principal mediators of the PACAP-mediated H1a induction response. In modulating H1a transcript and protein expression, these studies may implicate broad roles for PACAP and PAC1 receptor signaling in synaptic development and plasticity.

  2. Basement Structure and Styles of Active Tectonic Deformation in Central Interior Alaska

    NASA Astrophysics Data System (ADS)

    Dixit, N.; Hanks, C.

    2017-12-01

    Central Interior Alaska is one of the most seismically active regions in North America, exhibiting a high concentration of intraplate earthquakes approximately 700 km away from the southern Alaska subduction zone. Based on increasing seismological evidence, intraplate seismicity in the region does not appear to be uniformly distributed, but concentrated in several discrete seismic zones, including the Nenana basin and the adjacent Tanana basin. Recent seismological and neotectonics data further suggests that these seismic zones operate within a field of predominantly pure shear driven primarily by north-south crustal shortening. Although the location and magnitude of the seismic activity in both basins are well defined by a network of seismic stations in the region, the tectonic controls on intraplate earthquakes and the heterogeneous nature of Alaska's continental interior remain poorly understood. We investigated the current crustal architecture and styles of tectonic deformation of the Nenana and Tanana basins using existing geological, geophysical and geochronological datasets. The results of our study demonstrate that the basements of the basins show strong crustal heterogeneity. The Tanana basin is a relatively shallow (up to 2 km) asymmetrical foreland basin with its southern, deeper side controlled by the northern foothills of the central Alaska Range. Northeast-trending strike-slip faults within the Tanana basin are interpreted as a zone of clockwise crustal block rotation. The Nenana basin has a fundamentally different geometry; it is a deep (up to 8 km), narrow transtensional pull-apart basin that is deforming along the left-lateral Minto Fault. This study identifies two distinct modes of tectonic deformation in central Interior Alaska at present, and provides a basis for modeling the interplay between intraplate stress fields and major structural features that potentially influence the generation of intraplate earthquakes in the region.

  3. Evaluating Failure Mechanics of the Malpais Landslide, Eureka County, Nevada

    NASA Astrophysics Data System (ADS)

    Wilhite, C. P.; Carr, J. R.; Wallace, A. R.; Watters, R. J.

    2008-12-01

    The Malpais Landslide is located on the northeast end of the Shoshone Mountains in north-central Nevada. The 2.3 square kilometer slide originated near the crest of the Malpais Rim and flowed north into Whirlwind Valley. Given the proximity to Holocene faulting and active geothermal conditions, destabilizing forces include seismic activity, hydrothermal alteration, and changes in groundwater conditions. Approximately 3 km west of the slide is the Beowawe Geothermal Field, which is partially recharged along local faults and has altered geologic units throughout the slide area. The area contains two major normal faults (the approximately east striking Malpais Fault and the approximately north striking Dunphy Pass Fault) and numerous smaller faults. The most recent offset along the Malpais fault was approximately 7450 years B.P. (Wesnousky et al., 2005). The resulting scarp cannot be traced through the slide, therefore sliding occurred after that time (though previous sliding has not been ruled out). The stratigraphy in the slide area consists of a basal Paleozoic quartzite, unconformably overlain by Oligocene to Miocene conglomeratic to tuffaceous sediments with interbedded volcanic flows, capped by a sequence of mafic flow units. Except for the lowest sedimentary unit, Tts, all units dip approximately 25 degrees southeast. Tts was measured in outcrops east of the site and dips approximately 20 degrees north; since these outcrops could not be traced into the slide area, the dip of Tts at the slide is unknown. Point-load testing showed Tts to have a tensile strength of 3.12 MPa which is 55% weaker than the next weakest unit in the area. These factors, as well as Tts" semiconsolidated nature, suggest that Tts was the unit of failure. Further testing of the Malpais Landslide, as well as computer simulation, will be used to determine the cause of failure. This information and the examination of other nearby landslides may be helpful in assessing landslide risk in north-central Nevada and regions with similar characteristics. Reference: Wesnousky, S., Barron, A., Briggs, R., Caskey, S., Kumar, S., and Owen, L., 2005, Paleoseismic Transect Across the Northern Great Basin, Journal of Geophysical Research, v. 110.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campigotto, M.C.; Diaferio, A.; Hernandez, X.

    We discuss the phenomenology of gravitational lensing in the purely metric f (χ) gravity, an f ( R ) gravity where the action of the gravitational field depends on the source mass. We focus on the strong lensing regime in galaxy-galaxy lens systems and in clusters of galaxies. By adopting point-like lenses and using an approximate metric solution accurate to second order of the velocity field v / c , we show how, in the f (χ) = χ{sup 3/2} gravity, the same light deflection can be produced by lenses with masses smaller than in General Relativity (GR); this massmore » difference increases with increasing impact parameter and decreasing lens mass. However, for sufficiently massive point-like lenses and small impact parameters, f (χ) = χ{sup 3/2} and GR yield indistinguishable light deflection angles: this regime occurs both in observed galaxy-galaxy lens systems and in the central regions of galaxy clusters. In the former systems, the GR and f (χ) masses are compatible with the mass of standard stellar populations and little or no dark matter, whereas, on the scales of the core of galaxy clusters, the presence of substantial dark matter is required by our point-like lenses both in GR and in our approximate f (χ) = χ{sup 3/2} solution. We thus conclude that our approximate metric solution of f (χ) = χ{sup 3/2} is unable to describe the observed phenomenology of the strong lensing regime without the aid of dark matter.« less

  5. Helical filaments of human Dmc1 protein on single-stranded DNA: a cautionary tale.

    PubMed

    Yu, Xiong; Egelman, Edward H

    2010-08-20

    Proteins in the RecA/Rad51/RadA family form nucleoprotein filaments on DNA that catalyze a strand exchange reaction as part of homologous genetic recombination. Because of the centrality of this system to many aspects of DNA repair, the generation of genetic diversity, and cancer when this system fails or is not properly regulated, these filaments have been the object of many biochemical and biophysical studies. A recent paper has argued that the human Dmc1 protein, a meiotic homolog of bacterial RecA and human Rad51, forms filaments on single-stranded DNA with approximately 9 subunits per turn in contrast to the filaments formed on double-stranded DNA with approximately 6.4 subunits per turn and that the stoichiometry of DNA binding is different between these two filaments. We show using scanning transmission electron microscopy that the Dmc1 filament formed on single-stranded DNA has a mass per unit length expected from approximately 6.5 subunits per turn. More generally, we show how ambiguities in helical symmetry determination can generate incorrect solutions and why one sometimes must use other techniques, such as biochemistry, metal shadowing, or scanning transmission electron microscopy, to resolve these ambiguities. While three-dimensional reconstruction of helical filaments from EM images is a powerful tool, the intrinsic ambiguities that may be present with limited resolution are not sufficiently appreciated. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  6. CHAP III- CHARRING ABLATOR PROGRAM FOR ADVANCED INVESTIGATION OF THERMAL PROTECTION SYSTEMS FOR ENTRY

    NASA Technical Reports Server (NTRS)

    Stroud, C. W.

    1994-01-01

    The transient response of a thermal protection material to heat applied to the surface can be calculated using the CHAP III computer program. CHAP III can be used to analyze pyrolysis gas chemical kinetics in detail and examine pyrolysis reactions-indepth. The analysis includes the deposition of solid products produced by chemical reactions in the gas phase. CHAP III uses a modelling technique which can approximate a wide range of ablation problems. The energy equation used in CHAP III incorporates pyrolysis (both solid and gas reactions), convection, conduction, storage, work, kinetic energy, and viscous dissipation. The chemically reacting components of the solid are allowed to vary as a function of position and time. CHAP III employs a finite difference method to approximate the energy equations. Input values include specific heat, thermal conductivity, thermocouple locations, enthalpy, heating rates, and a description of the chemical reactions expected. The output tabulates the temperature at locations throughout the ablator, gas flow within the solid, density of the solid, weight of pyrolysis gases, and rate of carbon deposition. A sample case is included, which analyzes an ablator material containing several pyrolysis reactions subjected to an environment typical of entry at lunar return velocity. CHAP III is written in FORTRAN IV for batch execution and has been implemented on a CDC CYBER 170 series computer operating under NOS with a central memory requirement of approximately 102K (octal) of 60 bit words. This program was developed in 1985.

  7. Lens dose in routine head CT: comparison of different optimization methods with anthropomorphic phantoms.

    PubMed

    Nikupaavo, Ulla; Kaasalainen, Touko; Reijonen, Vappu; Ahonen, Sanna-Mari; Kortesniemi, Mika

    2015-01-01

    The purpose of this study was to study different optimization methods for reducing eye lens dose in head CT. Two anthropomorphic phantoms were scanned with a routine head CT protocol for evaluation of the brain that included bismuth shielding, gantry tilting, organ-based tube current modulation, or combinations of these techniques. Highsensitivity metal oxide semiconductor field effect transistor dosimeters were used to measure local equivalent doses in the head region. The relative changes in image noise and contrast were determined by ROI analysis. The mean absorbed lens doses varied from 4.9 to 19.7 mGy and from 10.8 to 16.9 mGy in the two phantoms. The most efficient method for reducing lens dose was gantry tilting, which left the lenses outside the primary radiation beam, resulting in an approximately 75% decrease in lens dose. Image noise decreased, especially in the anterior part of the brain. The use of organ-based tube current modulation resulted in an approximately 30% decrease in lens dose. However, image noise increased as much as 30% in the posterior and central parts of the brain. With bismuth shields, it was possible to reduce lens dose as much as 25%. Our results indicate that gantry tilt, when possible, is an effective method for reducing exposure of the eye lenses in CT of the brain without compromising image quality. Measurements in two different phantoms showed how patient geometry affects the optimization. When lenses can only partially be cropped outside the primary beam, organ-based tube current modulation or bismuth shields can be useful in lens dose reduction.

  8. Registration of Vehicle-Borne Point Clouds and Panoramic Images Based on Sensor Constellations.

    PubMed

    Yao, Lianbi; Wu, Hangbin; Li, Yayun; Meng, Bin; Qian, Jinfei; Liu, Chun; Fan, Hongchao

    2017-04-11

    A mobile mapping system (MMS) is usually utilized to collect environmental data on and around urban roads. Laser scanners and panoramic cameras are the main sensors of an MMS. This paper presents a new method for the registration of the point clouds and panoramic images based on sensor constellation. After the sensor constellation was analyzed, a feature point, the intersection of the connecting line between the global positioning system (GPS) antenna and the panoramic camera with a horizontal plane, was utilized to separate the point clouds into blocks. The blocks for the central and sideward laser scanners were extracted with the segmentation feature points. Then, the point clouds located in the blocks were separated from the original point clouds. Each point in the blocks was used to find the accurate corresponding pixel in the relative panoramic images via a collinear function, and the position and orientation relationship amongst different sensors. A search strategy is proposed for the correspondence of laser scanners and lenses of panoramic cameras to reduce calculation complexity and improve efficiency. Four cases of different urban road types were selected to verify the efficiency and accuracy of the proposed method. Results indicate that most of the point clouds (with an average of 99.7%) were successfully registered with the panoramic images with great efficiency. Geometric evaluation results indicate that horizontal accuracy was approximately 0.10-0.20 m, and vertical accuracy was approximately 0.01-0.02 m for all cases. Finally, the main factors that affect registration accuracy, including time synchronization amongst different sensors, system positioning and vehicle speed, are discussed.

  9. Successive post-Variscan stress fields in the French Massif Central and its borders (Western European plate): comparison with geodynamic data

    NASA Astrophysics Data System (ADS)

    Blés, J. L.; Bonijoly, D.; Castaing, C.; Gros, Y.

    1989-11-01

    Structural analysis and particularly microtectonic methods have made it possible to define the different stages of brittle deformation of the Massif Central basement and the surrounding sedimentary cover from the end of the Hercynian orogeny to the end of the Tertiary. During the Stephanian a compressional tectonic regime prevailed: regional faults appeared or were react vated reactivation as a result of initial N-S compression, becoming NW then E-W. These regional strike-slip faults caused local extension which led to the formation of small coal-bearing basins. This compressional regime, which marked the end of the formation of Pangea. was followed by a series of extension episodes: Permian-Triassic extension oscillating around N-S. E-W to NW-SE extension in the Early and Middle Jurassic and finally N-S to NE-SW extension in the Late Jurassic to Cretaceous. The normal faults formed during these episodes strongly influenced the distribution of emerging continents and sedimentary basins. From the Campanian (75 Ma) to the Present, the convergence of Africa and Eurasia involved the distribut on of stresses in the West European plate. Several tectonic episodes are distinguished in the Massif Central. During the Eocene approximately N-S compression predominated. General E-W extension in the Late Eocene-Oligocene resulted in grabens with general northerly strike, mainly in the centre of the Massif Central and on its east and southeast borders. Lastly, compression, varying from NW-SE to E-W, in the north and south of the Massif Central, prevailed during the Alpine orogenic phase at the end of the Miocene. These successive stages of brittle deformation are interpreted in the context of the evolution of the West European plate and its displacement in relation to the African plate. The correspondences between the major geodynamic periods and the distribution of stresses over the West European continent are noted as well as the problems which remair to be resolved.

  10. Centralities in simplicial complexes. Applications to protein interaction networks.

    PubMed

    Estrada, Ernesto; Ross, Grant J

    2018-02-07

    Complex networks can be used to represent complex systems which originate in the real world. Here we study a transformation of these complex networks into simplicial complexes, where cliques represent the simplices of the complex. We extend the concept of node centrality to that of simplicial centrality and study several mathematical properties of degree, closeness, betweenness, eigenvector, Katz, and subgraph centrality for simplicial complexes. We study the degree distributions of these centralities at the different levels. We also compare and describe the differences between the centralities at the different levels. Using these centralities we study a method for detecting essential proteins in PPI networks of cells and explain the varying abilities of the centrality measures at the different levels in identifying these essential proteins. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Effect of water temperature on diuresis-natriuresis: AVP, ANP, and urodilatin during immersion in men

    NASA Technical Reports Server (NTRS)

    Nakamitsu, S.; Sagawa, S.; Miki, K.; Wada, F.; Nagaya, K.; Keil, L. C.; Drummer, C.; Gerzer, R.; Greenleaf, J. E.; Hong, S. K.

    1994-01-01

    Effects of water temperature on diuresis, natriuresis, and associated endocrine responses during head-out immersion were studied in eight men during four 5-h experimental conditions: air control at 28 C and immersion at 34.5 C (thermoneutral (Tnt)), 36 C (above Tnt (aTnt)), and 32 C (below Tnt (bTnt). Esophageal temperature decreased by approximately 0.4 C in bTnt and increased by approximately 0.5 C in aTnt. Cardiac output increased by approximately 80% in aTnt and approximately 40% in bTnt while thoracic impedance, an index of central blood pooling, decreased by 7.5 ohms in bTnt (NS vs. Tnt) and 8.8 ohms in aTnt. Total peripheral resistance decreased at all temperatures (50% in aTnt, 20% in bTnt). Urine flow and Na(+) excretion increased by sixfold in bTnt and Tnt but by only threefold in aTnt. Creatinine clearance was unchanged while osmolal clearance (but not free water clearance) increased two-fold with all immersions. Plasma atrial natriuretic peptide (ANP), urinary urodilatin, and urinary guanosine 3',5'-cyclic monophosphate increased while plasma renin activity, aldosterone, and arginine vasopressin (AVP) decreased similarly at all temperatures. bTnt did not potentiate diuresis by selective attenuation of AVP. The overall natriuretic response exhibited a higher correlation with urodilatin than with ANP. Because diuresis and natriuresis were significantly attenuated in aTnt where central blood pooling was greater, we conclude that mechanisms other than the atrial stretch receptor reflex, i.e., urodilatin and effective arterial blood volume, may play more predominant roles in the mechanism of immersion-induced diuresis and natriuresis.

  12. Counterstreaming beams and flat-top electron distributions observed with Langmuir, Whistler, and compressional Alfvén waves in earth's magnetic tail.

    PubMed

    Teste, Alexandra; Parks, George K

    2009-02-20

    Relevant new clues to wave-particle interactions have been obtained in Earth's plasma sheet (PS). The plasma measurements made on Cluster spacecraft show that broadband (approximately 2-6 kHz) electrostatic emissions, in the PS boundary layer, are associated with cold counterstreaming electrons flowing at 5-12x10(3) km s(-1) through hot Maxwellian plasma. In the current sheet (CS), electromagnetic whistler mode waves (approximately 10-80 Hz) and compressional Alfvén waves (<2 Hz) are detected with flat-topped electron distributions whose cutoff speeds are approximately 15-17x10(3) km s(-1). These waves are damped in the central CS where |B|

  13. Algorithmic vs. finite difference Jacobians for infrared atmospheric radiative transfer

    NASA Astrophysics Data System (ADS)

    Schreier, Franz; Gimeno García, Sebastián; Vasquez, Mayte; Xu, Jian

    2015-10-01

    Jacobians, i.e. partial derivatives of the radiance and transmission spectrum with respect to the atmospheric state parameters to be retrieved from remote sensing observations, are important for the iterative solution of the nonlinear inverse problem. Finite difference Jacobians are easy to implement, but computationally expensive and possibly of dubious quality; on the other hand, analytical Jacobians are accurate and efficient, but the implementation can be quite demanding. GARLIC, our "Generic Atmospheric Radiation Line-by-line Infrared Code", utilizes algorithmic differentiation (AD) techniques to implement derivatives w.r.t. atmospheric temperature and molecular concentrations. In this paper, we describe our approach for differentiation of the high resolution infrared and microwave spectra and provide an in-depth assessment of finite difference approximations using "exact" AD Jacobians as a reference. The results indicate that the "standard" two-point finite differences with 1 K and 1% perturbation for temperature and volume mixing ratio, respectively, can exhibit substantial errors, and central differences are significantly better. However, these deviations do not transfer into the truncated singular value decomposition solution of a least squares problem. Nevertheless, AD Jacobians are clearly recommended because of the superior speed and accuracy.

  14. Targeted agents for patients with advanced/metastatic pancreatic cancer: A protocol for systematic review and network meta-analysis.

    PubMed

    Di, Baoshan; Pan, Bei; Ge, Long; Ma, Jichun; Wu, Yiting; Guo, Tiankang

    2018-03-01

    Pancreatic cancer (PC) is a devastating malignant tumor. Although surgical resection may offer a good prognosis and prolong survival, approximately 80% patients with PC are always diagnosed as unresectable tumor. National Comprehensive Cancer Network's (NCCN) recommended gemcitabine-based chemotherapy as efficient treatment. While, according to recent studies, targeted agents might be a better available option for advanced or metastatic pancreatic cancer patients. The aim of this systematic review and network meta-analysis will be to examine the differences of different targeted interventions for advanced/metastatic PC patients. We will conduct this systematic review and network meta-analysis using Bayesian method and according to Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) statement. To identify relevant studies, 6 electronic databases including PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), Web of science, CNKI (Chinese National Knowledge Infrastructure), and CBM (Chinese Biological Medical Database) will be searched. The risk of bias in included randomized controlled trials (RCTs) will be assessed using the Cochrane Handbook version 5.1.0. And we will use GRADE approach to assess the quality of evidence from network meta-analysis. Data will be analyzed using R 3.4.1 software. To the best of our knowledge, this systematic review and network meta-analysis will firstly use both direct and indirect evidence to compare the differences of different targeted agents and targeted agents plus chemotherapy for advanced/metastatic pancreatic cancer patients. This is a protocol of systematic review and meta-analysis, so the ethical approval and patient consent are not required. We will disseminate the results of this review by submitting to a peer-reviewed journal.

  15. Earth's partial pressure of CO2 over the past 100-500 Ma; evidence from Ce anomalies in mostly shallow seas (less than 200 m) as recorded in carbonate sediments, 2

    NASA Technical Reports Server (NTRS)

    Liu, Y.-G.; Reinhardt, J. W.; Schmitt, R. A.

    1993-01-01

    We reported the direct relationship of Ce anomalies recorded in 0.2-119 Ma CaCO3 sediments (Ce(sup A*)) to the Ce anomalies in the parental Pacific deep seawater (Ce(sup A)) and their relationship to atmospheric P(CO2) relative to present P(CO2). We have analyzed continental CaCO3 samples that were deposited in ancient oceans and shallow sea platforms less than 200 m over central USA, central Europe, China, and Saudi-Arabia/Oman. We have plotted Ce(sup A*) over the 75-470 Ma interval. For P(CO2) calculations, we assumed as a reference standard the less than 200 m mixed Pacific Ocean with a Ce(sup A) geometric mean of 0.22 and a range of 0.10-0.43. Because P(CO2) values obtained from reliable deep Pacific Ocean carbonates in the 67-119 Ma interval were similar to the present P(CO2) values, we have drawn a 1.0 ratio for that interval. Although there is considerable scatter among the approximately 150 Ma carbonates, the average Ce(sup A*) value suggests that P(CO2) increased during the early Cretaceous, from 1.0X at approximately 120 Ma to about 1.4X at approximately 150 Ma. At approximately 250 Ma, the average Ce(sup A*) in 13 shallow sea China carbonates agrees well with the single and more reliable approximately 250 Ma China carbonate deposited in deeper open platform. We suggest that P(CO2) ranged from 1.4-1.7X over the Jurassic and Triassic periods. At approximately 280 Ma, three China carbonates deposited in deeper open platforms and therefore considered more reliable are consistent with a European carbonate, which indicate Ce(sup A) and P(CO2) values similar to the present. The minimum at this time corresponds to the great Permo-Carboniferous glaciation. From 280 Ma to 470 Ma, the trend favors increasing Ce(sup A*) and corresponding P(CO2) values between 1.9-2.7X, with a more reliable value closer to 2.7X at 430 Ma because of the unknown higher temperature in the less than 100 m seawater over continental USA which was located just south of the equator at approximately 430 Ma.

  16. Insulin resistance in prepubertal obese children correlates with sex-dependent early onset metabolomic alterations.

    PubMed

    Mastrangelo, A; Martos-Moreno, G Á; García, A; Barrios, V; Rupérez, F J; Chowen, J A; Barbas, C; Argente, J

    2016-10-01

    Insulin resistance (IR) is usually the first metabolic alteration diagnosed in obese children and the key risk factor for development of comorbidities. The factors determining whether or not IR develops as a result of excess body mass index (BMI) are still not completely understood. This study aimed to elucidate the mechanisms underpinning the predisposition toward hyperinsulinemia-related complications in obese children by using a metabolomic strategy that allows a profound interpretation of metabolic profiles potentially affected by IR. Serum from 60 prepubertal obese children (30 girls/30 boys, 50% IR and 50% non-IR in each group, but with similar BMIs) were analyzed by using liquid chromatography-mass spectrometry, gas chromatography-mass spectrometry and capillary electrophoresis-mass spectrometry following an untargeted metabolomics approach. Validation was then performed on a group of 100 additional children with the same characteristics. When obese children with and without IR were compared, 47 metabolites out of 818 compounds (P<0.05) obtained after data pre-processing were found to be significantly different. Bile acids exhibit the greatest changes (that is, approximately a 90% increase in IR). The majority of metabolites differing between groups were lysophospholipids (15) and amino acids (17), indicating inflammation and central carbon metabolism as the most altered processes in impaired insulin signaling. Multivariate analysis (OPLS-DA models) showed subtle differences between groups that were magnified when females were analyzed alone. Inflammation and central carbon metabolism, together with the contribution of the gut microbiota, are the most altered processes in obese children with impaired insulin signaling in a sex-specific fashion despite their prepubertal status.

  17. The Evolution History of South China Sea: a Synthesis of Recent Geophysical, Geological, and Geochemical Results

    NASA Astrophysics Data System (ADS)

    Xue, M.; Li, L.; Chen, L.

    2016-12-01

    South China Sea (SCS) is located in the continental margin of Eurasia plate, where different geological blocks/tectonic plates interact. The dynamic mechanism of the formation of South China Sea (SCS) has been debated for decades. In this study, we first synthesize our geophysical results obtained in South China Sea, including an updated 3D velocity model from surface tomography using surrounding land stations and regional earthquakes, and shear wave splitting results obtained at surrounding land stations and OBS, using local, regional, and teleseismic earthquakes. The observed splitting results in South China Sea are complex: the fast polarization direction beneath the central basin is approximately NE-SW, nearly parallel to the extinct ridge in the central basin of SCS; however, the fast axis within the slab is trench-parallel outside the ridge subduction region. In 3D velocity models, subducting slabs are observed as dipping high velocity anomalies, and discontinuous low velocities are observed above the subduction slab, as well as in the basin. How the splitting observations are connected with the velocity models? How observations are linked to one another? How are the observations in central basin linked with surrounding region? We are aiming to link these observations themselves as well as with newly published results from geophysics, geochemistry, and geology in this region. Such a synthesis will improve our understanding about the evolution of South China Sea and facilitate new ideas.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nakamura, K.; Jacob, K.

    Flank eruptions of polygenetic volcanoes are regarded as surface expressions of radial dikes. Therefore, the approximate pattern of radial dikes is revealed by the distribution of sites of flank eruptions. Bending of radial dikes into a preferred orientation reveals the maximum horizontal compressive stress axis. The Aleutian and Alaskan volcanoes are studied using this concept and 28 orientations of the maximum horizontal compressive stress axis are obtained. Combined with the orientation of similar quality obtained from active faults in central Alaska the trajectories of the maximum horizontal stress for the entire area during recent 10,000 to 100,000 years or longermore » is depicted. Along the Aleutian-Alaska volcanic belt, the maximum horizontal compression parallels the direction of relative motion between the North American and Pacific plates. Seven roughly east-westerly orientations are obtained from west Alaskan and Bering Sea volcanoes. In central Alaska, the trajectories spread north-westward in a fan shape with axis of symmetry in a N25/sup 0/W direction passing through the easternmost part of the Aleutian trench. The trajectories continue westward onto the Bering Sea shelf with a generally westerly trend. The overall pattern of orientations of maximum horizontal compressive stresses seems to be explained by the convergent plate motions along. An exception is the high--angle relationship between the maximum horizontal stress orientation in the central Aleutians and the immediate back-arc region, which suggests that in the back-arc region the tectonic stress system has a different origin probably at considerable depth beneath the crust.« less

  19. Neutronic reactor

    DOEpatents

    Wende, Charles W. J.

    1976-08-17

    A safety rod for a nuclear reactor has an inner end portion having a gamma absorption coefficient and neutron capture cross section approximately equal to those of the adjacent shield, a central portion containing materials of high neutron capture cross section and an outer end portion having a gamma absorption coefficient at least equal to that of the adjacent shield.

  20. 76 FR 50541 - Endangered and Threatened Wildlife and Plants; Designation of Revised Critical Habitat for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... centimeters (5.8 inches) in length. The flycatcher is one of four subspecies of the willow flycatcher... clustering into two groups separated approximately along the currently recognized boundary; however, they... central Arizona. Flycatchers are believed to exist and interact as groups of metapopulations (Service 2002...

  1. Auke Lake Campus Site Development Plan.

    ERIC Educational Resources Information Center

    Alaska Univ., Juneau. Dept. of Facilities Planning and Construction.

    The University of Alaska, Juneau (UAJ), is the center for the University of Alaska Southeast and includes both a senior college and a community college. Most of the university facilities within the Juneau area are on the Auke Lake Campus, approximately 12 miles northwest of central Juneau. This report delineates the location of the campus, then…

  2. Recommendations for constructing forest stream crossings to control soil losses

    Treesearch

    Pamela J. Edwards; Jingxin Wang; Joshua T. Stedman

    2009-01-01

    Stream water samples were collected once daily and throughout storms from a small forested watershed in north central West Virginia for approximately 8 years. The turbidities of the samples were measured to determine how water quality changed in response to the construction of three associated stream crossings. The influence of the...

  3. Using a soil moisture and precipitation network for satellite validation

    USDA-ARS?s Scientific Manuscript database

    A long term in situ network for the study of soil moisture and precipitation was deployed in north central Iowa, in cooperation between USDA and NASA. A total of 20 dual precipitation gages were established across a watershed landscape with an area of approximately 600 km2. In addition, four soil mo...

  4. Introducing Winter Canola in the Wheat-Fallow Region of North Central Washington

    USDA-ARS?s Scientific Manuscript database

    Approximately 60% of the cereal and grain legume production areas of the Pacific Northwest are characterized by the winter wheat/summer fallow system. This system is plagued by winter annual grass weeds such as jointed goatgrass, feral rye, and downy brome. Growers are becoming more interested in pr...

  5. 33 CFR 110.9 - Wells Harbor, Maine.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Wells Harbor, Maine. 110.9... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.9 Wells Harbor, Maine. (a) Anchorage “A”. All of the... approximately 5,800 sq. yards, encompassing the central portion of Wells Harbor. (b) Anchorage “B”. All of the...

  6. Continuity and Change: The Integration of Oxford University's Libraries

    ERIC Educational Resources Information Center

    Moran, Barbara B.

    2005-01-01

    Prior to 1997, the University of Oxford in Great Britain had approximately one hundred autonomous libraries with little coordination of services, collection development, or management among them. In that year a new director was hired with the mandate to integrate many of these libraries into one centralized system. Over the past seven years…

  7. 78 FR 19335 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... disapproving the application. The total annual burden imposed by Rule 15a-4 is approximately 8.46 hours, based... of the Exchange Act; (2) to develop a central information resource where members of the public may... the PRA that does not display a valid OMB control number. The public may view background documentation...

  8. A Precarious Position of Power: Soviet School Directors in the 1930s

    ERIC Educational Resources Information Center

    Ewing, E. Thomas

    2009-01-01

    In September 1931, the Communist Party Central Committee, the highest political authority in the Soviet Union, declared that "single person rule" ("edinonachalie") should prevail in the administration of schools. The history of approximately 100,000 school directors in the 1930s was shaped by a rapid expansion in numbers as…

  9. Evaluation of evapotranspiration estimates derived using satellite remote sensing for irrigation management in California vineyards

    USDA-ARS?s Scientific Manuscript database

    Water management is a critical aspect of successful grape production in California’s Central Valley, which represents nearly 1 million acres of grape production valued at approximately 6 billion dollars. Despite competing water use interest and a reduction in water availability over much of Californ...

  10. An intercomparison of evapotranspiration estimates derived using thermal-based satellite remote sensing for irrigation management in California vineyards

    USDA-ARS?s Scientific Manuscript database

    Irrigation in the central valley of California is essential for successful wine grape production, which represents nearly 1 million acres valued at approximately 6 billion dollars. With reductions in water availability and competing water use interests in much of California, there is a critical need...

  11. Environmental Assessment for Central Wyoming Relay Node, Site Number RN 8C928WY

    DTIC Science & Technology

    1993-02-19

    alkali sacaton, Indian ricegrass, basin wild rye, thread leaf sedge, side oats grama, and milk vetch (SCS, 1990). 3-4 The SSA contains an abundance of free...Russian thistle , indicating that its native vegetation has been disturbed. Thermopolis, the nearest residential community, is approximately 7.5 miles

  12. 76 FR 24080 - Houston District Office Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... is issuing this notice to announce the location, date, time, and agenda for the next meeting of the... will be held on May 24, 2011 from approximately 11:30 a.m. to 12:30 p.m. Central Standard Time... we can better serve our community and to create new networking opportunities with the Houston...

  13. Finite size and geometrical non-linear effects during crack pinning by heterogeneities: An analytical and experimental study

    NASA Astrophysics Data System (ADS)

    Vasoya, Manish; Unni, Aparna Beena; Leblond, Jean-Baptiste; Lazarus, Veronique; Ponson, Laurent

    2016-04-01

    Crack pinning by heterogeneities is a central toughening mechanism in the failure of brittle materials. So far, most analytical explorations of the crack front deformation arising from spatial variations of fracture properties have been restricted to weak toughness contrasts using first order approximation and to defects of small dimensions with respect to the sample size. In this work, we investigate the non-linear effects arising from larger toughness contrasts by extending the approximation to the second order, while taking into account the finite sample thickness. Our calculations predict the evolution of a planar crack lying on the mid-plane of a plate as a function of material parameters and loading conditions, especially in the case of a single infinitely elongated obstacle. Peeling experiments are presented which validate the approach and evidence that the second order term broadens its range of validity in terms of toughness contrast values. The work highlights the non-linear response of the crack front to strong defects and the central role played by the thickness of the specimen on the pinning process.

  14. Farming and fishing in the wake of El Nino

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tibbetts, J.

    How does the periodic warming of the waters of the central Pacific relate to global climate change and food production? In Queensland, Australia, savvy farmers keep a sharp eye on signs of El Nino, which usually brings drought that withers the state`s winter wheat crop. Returning every four years on average and usually lasting approximately a year, El Nino is an unusual warming in the central Pacific that builds storms and disrupts wind patterns, turning weather upside down in far-removed regions. But El Nino took scientists by surprise when it persisted from 1991 to 1995. This was the first timemore » that El Nino had lasted for more than three years since monitoring began in the 1870s. And true to form, El Nino of 1991-1995 brought extreme drought to Queensland, in north-eastern Australia, drying out farmland and costing the state economy approximately $1 billion (Australian) a year. The drought, for example, dropped rainfall levels to all-time lows in Toowoomba, one of the state`s prime cereal-growing regions.« less

  15. Hydrology of the Floral City Pool of Tsala Apopka Lake, west-central Florida

    USGS Publications Warehouse

    Bradner, L.A.

    1988-01-01

    Tsala Apopka Lake, in west-central Florida, has an area of about 19,000 acres and is divided into three water-management pools, with the Floral City Pool, the most upgradient. The Floral City Pool, which has a surface area of approximately 4,750 acres, contains an extensive combination of lakes, wetlands, and connecting canals. The Pool receives inflow from the Withlacoochee River through two canals. Outflow is through one manmade canal and one natural slough. Canal flow is partially controlled by manmade structures. A cumulative deficit of 19.4 inches of rainfall from August 1984 through May 1985 reduced surface-water inflow to the Floral City Pool to about 0.5 cu ft/sec by May 1985. During May 1985, pool levels declined approximately 0.04 ft/day. By the end of May, there was no observable outflow. From June 1985 through September 1985, 39.8 inches of rainfall caused above-average inflow to the Floral City Pool and a pool-level increase of 6.2 ft. The inflow of 340 CFS nearly equaled the outflow of 338 CFS by the end of September. (USGS)

  16. Temporal-varying failures of nodes in networks

    NASA Astrophysics Data System (ADS)

    Knight, Georgie; Cristadoro, Giampaolo; Altmann, Eduardo G.

    2015-08-01

    We consider networks in which random walkers are removed because of the failure of specific nodes. We interpret the rate of loss as a measure of the importance of nodes, a notion we denote as failure centrality. We show that the degree of the node is not sufficient to determine this measure and that, in a first approximation, the shortest loops through the node have to be taken into account. We propose approximations of the failure centrality which are valid for temporal-varying failures, and we dwell on the possibility of externally changing the relative importance of nodes in a given network by exploiting the interference between the loops of a node and the cycles of the temporal pattern of failures. In the limit of long failure cycles we show analytically that the escape in a node is larger than the one estimated from a stochastic failure with the same failure probability. We test our general formalism in two real-world networks (air-transportation and e-mail users) and show how communities lead to deviations from predictions for failures in hubs.

  17. Intermittency via moments and distributions in central O+Cu collisions at 14. 6 A[center dot]GeV/c

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tannenbaum, M.J.

    Fluctuations in pseudorapidity distributions of charged particles from central (ZCAL) collisions of [sup 16]O+Cu at 14.6 A[center dot]GeV/c have been analyzed by Ju Kang using the method of scaled factorial moments as a function of the interval [delta][eta] an apparent power-law growth of moments with decreasing interval is observed down to [delta][eta] [approximately] 0.1, and the measured slope parameters are found to obey two scaling rules. Previous experience with E[sub T] distributions suggested that fluctuations of multiplicity and transverse energy can be well described by Gamma or Negative Binomial Distributions (NBD) and excellent fits to NBD were obtained in allmore » [delta][eta] bins. The k parameter of the NBD fit was found to increase linearly with the [delta][eta] interval, which due to the well known property of the NBD under convolution, indicates that the multiplicity distributions in adjacent bins of pseudorapidity [delta][eta] [approximately] 0.1 are largely statistically independent.« less

  18. Intermittency via moments and distributions in central O+Cu collisions at 14.6 A{center_dot}GeV/c

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tannenbaum, M.J.; The E802 Collaboration

    Fluctuations in pseudorapidity distributions of charged particles from central (ZCAL) collisions of {sup 16}O+Cu at 14.6 A{center_dot}GeV/c have been analyzed by Ju Kang using the method of scaled factorial moments as a function of the interval {delta}{eta} an apparent power-law growth of moments with decreasing interval is observed down to {delta}{eta} {approximately} 0.1, and the measured slope parameters are found to obey two scaling rules. Previous experience with E{sub T} distributions suggested that fluctuations of multiplicity and transverse energy can be well described by Gamma or Negative Binomial Distributions (NBD) and excellent fits to NBD were obtained in all {delta}{eta}more » bins. The k parameter of the NBD fit was found to increase linearly with the {delta}{eta} interval, which due to the well known property of the NBD under convolution, indicates that the multiplicity distributions in adjacent bins of pseudorapidity {delta}{eta} {approximately} 0.1 are largely statistically independent.« less

  19. Output characteristics of SASE-driven short wavelength FEL`s

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fawley, W.M.

    This paper investigates various properties of the ``microspikes`` associated with self-amplified spontaneous emission (SASE) in a short wavelength free-electron laser (FEL). Using results from the 2-D numerical simulation code GINGER, we confirm theoretical predictions such as the convective group velocity in the exponential gain regime. In the saturated gain regime beyond the initial saturation, we find that the average radiation power continues to grow with an approximately linearly dependence upon undulator length. Moreover, the spectrum significantly broadens and shifts in wavelength to the redward direction, with{ital P(w)} approaching a constant, asymptotic value. This is in marked contrast to the exponentialmore » gain regime where the spectrum steadily narrows, {ital P(w)} grows, and the central wavelength remains constant with {ital z}. Via use of a spectrogram diagnostic {ital S(w,t)}, it appears that the radiation pattern in the saturated gain regime is composed of an ensemble of distinct ``sinews`` whose widths AA remain approximately constant but whose central wavelengths can ``chirp`` by varying a small extent with {ital t}.« less

  20. Centralized Fabric Management Using Puppet, Git, and GLPI

    NASA Astrophysics Data System (ADS)

    Smith, Jason A.; De Stefano, John S., Jr.; Fetzko, John; Hollowell, Christopher; Ito, Hironori; Karasawa, Mizuki; Pryor, James; Rao, Tejas; Strecker-Kellogg, William

    2012-12-01

    Managing the infrastructure of a large and complex data center can be extremely difficult without taking advantage of recent technological advances in administrative automation. Puppet is a seasoned open-source tool that is designed for enterprise class centralized configuration management. At the RHIC and ATLAS Computing Facility (RACF) at Brookhaven National Laboratory, we use Puppet along with Git, GLPI, and some custom scripts as part of our centralized configuration management system. In this paper, we discuss how we use these tools for centralized configuration management of our servers and services, change management requiring authorized approval of production changes, a complete version controlled history of all changes made, separation of production, testing and development systems using puppet environments, semi-automated server inventory using GLPI, and configuration change monitoring and reporting using the Puppet dashboard. We will also discuss scalability and performance results from using these tools on a 2,000+ node cluster and 400+ infrastructure servers with an administrative staff of approximately 25 full-time employees (FTEs).

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