Extending the amygdala in theories of threat processing

PubMed Central

Fox, Andrew S.; Oler, Jonathan A.; Tromp, Do P.M.; Fudge, Julie L.; Kalin, Ned H.

2015-01-01

The central extended amygdala is an evolutionarily conserved set of interconnected brain regions that play an important role in threat processing to promote survival. Two core components of the central extended amygdala, the central nucleus of the amygdala (Ce) and the lateral bed nucleus of the stria terminalis (BST) are highly similar regions that serve complimentary roles by integrating fear- and anxiety-relevant information. Survival depends on the central extended amygdala's ability to rapidly integrate and respond to threats that vary in their immediacy, proximity, and characteristics. Future studies will benefit from understanding alterations in central extended amygdala function in relation to stress-related psychopathology. PMID:25851307

Challenges Facing Managers in Managing Conflict in Schools in the South and South Central Regions of Botswana

ERIC Educational Resources Information Center

Morake, Nnior Machomi; Monobe, Ratau John; Dingwe, Stephonia

2011-01-01

The purpose of this study was to examine the challenges facing managers in managing conflict in schools of South and South Central Regions of Botswana. In this study, the schedule of interview was used to collect empirical data. A random sample of 50 school managers and deputy school managers was selected for interviews. Major findings of the…

The Complex Life Experience of First-Generation College Students Who Are Working Adults in the Appalachian Region of the United States: A Phenomenological Study

ERIC Educational Resources Information Center

Thurman, Deborah Elizabeth

2016-01-01

The purpose of this transcendental phenomenological study was to describe and understand the complexity of life experiences for first-generation college students or recent graduates who are working adults in the Central and South-Central Appalachian region of the United States in light of the construct resilience and how purposefully selected…

Transmission Reinforcements in the Central American Regional Power System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elizondo, Marcelo A.; Vallem, Mallikarjuna R.; Samaan, Nader A.

The Central American regional interconnected power system (SER) connects the countries members of the Central American regional electricity market (MER): Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, and Panama. The SER was a result of a long term regional effort, and was initially conceived to transfer 300 MW between countries. However, the current transfer limits between countries range from 70 MW to 300 MW. Regional entities, like CRIE (Regional Commission of Electrical Interconnection), EOR (Central American Regional System Operator), and CDMER (Board of Directors of the Central American Market) are working on coordinating the national transmission expansion plans with regionalmore » transmission planning efforts. This paper presents experience in Central America region to recommend transmission reinforcements to achieve 300 MW transfer capacity between any pair of member countries of the Central American regional electricity market (MER). This paper also provides a methodology for technical analysis and for coordination among the regional and national entities. This methodology is unique for transmission systems of these characteristics.« less

The architecture of the joint head cuticle and its transition to the arthrodial membrane in the terrestrial crustacean Porcellio scaber.

PubMed

Ruangchai, Sukhum; Reisecker, Christian; Hild, Sabine; Ziegler, Andreas

2013-04-01

The cuticle of terrestrial isopods is an interesting model for the study of structure-function relationships in biological composite materials. Its organic matrix has a hierarchically organised structure, and type and phase of the mineral compound can vary. The cuticle forms functionally diverse skeletal elements whose properties are adapted to their specific functions. In order to better understand the relation between structure, composition and function of isopod cuticle, we studied the structure and composition of the joint head that is part of the pereiopod's basis. It consists of a central region, whose shape fits well into the joint socket, and an edge region that is connected to the soft arthrodial membrane and protects the central region from mechanical load. The cuticle architecture of the joint head has local variations in structure and composition. In the central region the cuticle is similar to the previously published tergite cuticle. High concentrations of amorphous calcium phosphate are located in the endocuticle suggesting a coexistence with amorphous calcium carbonate. The edge region has an unexpected organisation characterised by thickening of the epi- and exocuticle and an unusual unidirectional orientation of chitin-protein fibrils within the endocuticle. The concentrations of phosphate are considerably higher than in the central region. The overall differentiation in the cuticular architecture of the edge in comparison to the central region reflects the adaptation to mechanical strains the cuticle has to sustain during contraction of extensor muscles, and to the structural and compositional transition from the edge to the connecting arthrodial membrane. Copyright © 2013 Elsevier Inc. All rights reserved.

Migratory connectivity of american woodcock using band return data

USGS Publications Warehouse

Moore, Joseph D.; Krementz, David G.

2017-01-01

American woodcock (Scolopax minor) are managed as a Central and an Eastern population in the United States and Canada based on band return data showing little crossover between populations or management regions. The observed proportion of crossover between management regions, however, depends on the criteria used to subset the band return data. We analyzed the amount of crossover between management regions using only band return records that represent complete migrations between the breeding and wintering grounds by using only band return records in which the capture took place during the breeding season and the band recovery took place during the wintering season or vice versa (n = 224). Additionally, we applied spatial statistics and a clustering algorithm to investigate woodcock migratory connectivity using this subset of migratory woodcock band return records. Using raw counts, 17.9% of records showed crossover between management regions, a higher proportion than the <5% crossover reported in studies that did not use only migratory band returns. Our results showed woodcock from the breeding grounds in the Central Region largely migrate to destinations within the Central Region, whereas woodcock from the breeding grounds in the Eastern Region migrate to destinations across the entire wintering range and mix with individuals from the Central Region. Using the division coefficient, we estimated that 54% of woodcock from the breeding grounds of the Eastern Region migrate to the Central Region wintering grounds. Our result that many woodcock from separate regions of the breeding grounds mix on the wintering grounds has implications for the 2-region basis for woodcock management. Elucidating finer scale movement patterns among regions provides a basis for reassessing the need for separate management regions to ensure optimal conservation and management of the species.

Perceptual load in different regions of the visual scene and its relevance for driving.

PubMed

Marciano, Hadas; Yeshurun, Yaffa

2015-06-01

The aim of this study was to better understand the role played by perceptual load, at both central and peripheral regions of the visual scene, in driving safety. Attention is a crucial factor in driving safety, and previous laboratory studies suggest that perceptual load is an important factor determining the efficiency of attentional selectivity. Yet, the effects of perceptual load on driving were never studied systematically. Using a driving simulator, we orthogonally manipulated the load levels at the road (central load) and its sides (peripheral load), while occasionally introducing critical events at one of these regions. Perceptual load affected driving performance at both regions of the visual scene. Critically, the effect was different for central versus peripheral load: Whereas load levels on the road mainly affected driving speed, load levels on its sides mainly affected the ability to detect critical events initiating from the roadsides. Moreover, higher levels of peripheral load impaired performance but mainly with low levels of central load, replicating findings with simple letter stimuli. Perceptual load has a considerable effect on driving, but the nature of this effect depends on the region of the visual scene at which the load is introduced. Given the observed importance of perceptual load, authors of future studies of driving safety should take it into account. Specifically, these findings suggest that our understanding of factors that may be relevant for driving safety would benefit from studying these factors under different levels of load at different regions of the visual scene. © 2014, Human Factors and Ergonomics Society.

40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...

40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...

40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...

40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...

40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...

40 CFR 81.105 - South Central Pennsylvania Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false South Central Pennsylvania Intrastate... Designation of Air Quality Control Regions § 81.105 South Central Pennsylvania Intrastate Air Quality Control Region. The South Central Pennsylvania Intrastate Air Quality Control Region consists of the territorial...

40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 18 2012-07-01 2012-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...

40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 18 2013-07-01 2013-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...

40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...

40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 18 2014-07-01 2014-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...

40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 17 2011-07-01 2011-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...

Regional variations in hypertension prevalence and management in Germany: results from the German Health Interview and Examination Survey (DEGS1).

PubMed

Diederichs, Claudia; Neuhauser, Hannelore

2014-07-01

This study analyzed regional differences in blood pressure (BP) distribution and management in Germany 2008-2011 in a nationwide study. The analyses were based on standardized BP measurements and anatomical therapeutic chemical classification-coded medication from the population-based German Health Interview and Examination Survey (DEGS1) 2008-2011 (N = 7074, 18-79 years, 180 study points, five regions: Central-East, South, Central-West, North-West, and North-East). Regional differences were tested between the region with the highest and lowest values. Regional variations were observed in mean SBP, mean DBP, and the prevalence of hypertension in both sexes, as well as awareness, treatment, and control in men. Differences in blood pressure (in mmHg) between Central-East, the region with the highest BP level and the region with the lowest BP level, were SBP 3.2 and DBP 2.5 in men and SBP 4.5 and DBP 2.4 in women. In Central-East 39% of men and 40% of women had hypertension, versus 30% of men in the North-West and 26% of women in the South. The percentage of aware, treated, and controlled men ranged between 92, 78, and 56% in the North-East and 74, 59, and 41% in the South, respectively. After multivariate adjustment for sociodemographic variables and hypertension risk factors, geographical differences persisted for hypertension prevalence in women and hypertension awareness and treatment in men. So far, national surveys allowed only BP comparisons along the former East-West border and showed more elevated BP in the East. New analyses suggest regional differences with both the most and the least favorable results in the two neighboring parts of former East Germany.

Autonomic responses to exercise: where is central command?

PubMed

Williamson, J W

2015-03-01

A central command is thought to involve a signal arising in a central area of the brain eliciting a parallel activation of the autonomic nervous system and skeletal muscle contraction during exercise. Although much of the neural circuitry involved in autonomic control has been identified, defining the specific higher brain region(s) serving in a central command capacity has proven more challenging. Investigators have been faced with redundancies in regulatory systems, feedback mechanisms and the complexities ofhuman neural connectivity. Several studies have attempted to address these issues and provide more definitive neuroanatomical information. However, none have clearly answered the question, "where is central command?" Copyright © 2014 Elsevier B.V. All rights reserved.

40 CFR 81.127 - Central New York Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central New York Intrastate Air... Air Quality Control Regions § 81.127 Central New York Intrastate Air Quality Control Region. The Central New York Intrastate Air Quality Control Region consists of the territorial area encompassed by the...

40 CFR 81.95 - Central Florida Intrastate Air Quality Control Region.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Quality Control Regions § 81.95 Central Florida Intrastate Air Quality Control Region. The Central Florida Intrastate Air Quality Control Region consists of the territorial area encompassed by the boundaries of the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Central Florida Intrastate Air Quality...

40 CFR 81.95 - Central Florida Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Quality Control Regions § 81.95 Central Florida Intrastate Air Quality Control Region. The Central Florida Intrastate Air Quality Control Region consists of the territorial area encompassed by the boundaries of the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Florida Intrastate Air Quality...

Preliminary results of ERTS-investigations by W-German investigations. [multidisciplinary geoscientific experiments in central Germany and hydrogeology of Argentina Pampas

NASA Technical Reports Server (NTRS)

Muehlfeld, R.

1974-01-01

Results are presented of West German investigations into multidisciplinary geoscientific experiments in central Germany and the Alps, and hydrogeological investigations in the Pampa of Argentina based on ERTS-1 data. The main goals of the investigation were achieved. The studies have given a good idea of the possibilities and limitations of ERTS imagery depending on the objectives in question and on the geographical conditions of the areas under investigation. Even in the well known region of central Europe, ERTS has proven its ability of improving present knowledge. In fields such as pollution monitoring and regional planning the satellite techniques should have distinct practical value. For any regional study of less known areas, the value of ERTS imagery can hardly be overestimated.

Use of ERIC Materials by Certified School Personnel in Three Educational Service Regions in West Central Illinois.

ERIC Educational Resources Information Center

MacVean, Donald S.

Designed to determine to what extent the Educational Resources Information Center (ERIC) products and services are utilized by certified school personnel, this study found that, on the average, 25.1% of the teachers, librarians, counselors, and administrators in three educational service regions in west central Illinois have used Resources in…

North Central Region 4-H Volunteers: Documenting Their Contributions and Volunteer Development

ERIC Educational Resources Information Center

Nippolt, Pamela Larson; Pleskac, Sue; Schwartz, Vicki; Swanson, Doug

2012-01-01

Documenting volunteer contributions strengthens Extension partnerships with volunteers. A team of North Central Region 4-H volunteer specialists collaborated to conduct a study of 4-H volunteer contributions and impacts related to working with youth within the 4-H program. Over three thousand (3,332) 4-H volunteers from throughout the 12-state…

High-fat diet feeding differentially affects the development of inflammation in the central nervous system.

PubMed

Guillemot-Legris, Owein; Masquelier, Julien; Everard, Amandine; Cani, Patrice D; Alhouayek, Mireille; Muccioli, Giulio G

2016-08-26

Obesity and its associated disorders are becoming a major health issue in many countries. The resulting low-grade inflammation not only affects the periphery but also the central nervous system. We set out to study, in a time-dependent manner, the effects of a high-fat diet on different regions of the central nervous system with regard to the inflammatory tone. We used a diet-induced obesity model and compared at several time-points (1, 2, 4, 6, 8, and 16 weeks) a group of mice fed a high-fat diet with its respective control group fed a standard diet. We also performed a large-scale analysis of lipids in the central nervous system using HPLC-MS, and we then tested the lipids of interest on a primary co-culture of astrocytes and microglial cells. We measured an increase in the inflammatory tone in the cerebellum at the different time-points. However, at week 16, we evidenced that the inflammatory tone displayed significant differences in two different regions of the central nervous system, specifically an increase in the cerebellum and no modification in the cortex for high-fat diet mice when compared with chow-fed mice. Our results clearly suggest region-dependent as well as time-dependent adaptations of the central nervous system to the high-fat diet. The differences in inflammatory tone between the two regions considered seem to involve astrocytes but not microglial cells. Furthermore, a large-scale lipid screening coupled to ex vivo testing enabled us to identify three classes of lipids-phosphatidylinositols, phosphatidylethanolamines, and lysophosphatidylcholines-as well as palmitoylethanolamide, as potentially responsible for the difference in inflammatory tone. This study demonstrates that the inflammatory tone induced by a high-fat diet does not similarly affect distinct regions of the central nervous system. Moreover, the lipids identified and tested ex vivo showed interesting anti-inflammatory properties and could be further studied to better characterize their activity and their role in controlling inflammation in the central nervous system.

The central spheroids of Milky Way mass-sized galaxies

NASA Astrophysics Data System (ADS)

Tissera, Patricia B.; Machado, Rubens E. G.; Carollo, Daniela; Minniti, Dante; Beers, Timothy C.; Zoccali, Manuela; Meza, Andres

2018-01-01

We study the properties of the central spheroids located within 10 kpc of the centre of mass of Milky Way mass-sized galaxies simulated in a cosmological context. The simulated central regions are dominated by stars older than 10 Gyr, mostly formed in situ, with a contribution of ∼30 per cent from accreted stars. These stars formed in well-defined starbursts, although accreted stars exhibit sharper and earlier ones. The fraction of accreted stars increases with galactocentric distance, so that at a radius of ∼8-10 kpc, a fraction of ∼40 per cent, on average, is detected. Accreted stars are slightly younger, lower metallicity, and more α-enhanced than in situ stars. A significant fraction of old stars in the central regions come from a few (2-3) massive satellites (∼1010 M⊙). The bulge components receive larger contributions of accreted stars formed in dwarfs smaller than ∼109.5 M⊙. The difference between the distributions of ages and metallicities of old stars is thus linked to the accretion histories - those central regions with a larger fraction of accreted stars are those with contributions from more massive satellites. The kinematical properties of in situ and accreted stars are consistent with the latter being supported by their velocity dispersions, while the former exhibit clear signatures of rotational support. Our simulations demonstrate a range of characteristics, with some systems exhibiting a co-existing bar and spheroid in their central regions, resembling in some respect the central region of the Milky Way.

Assessing Lightning and Wildfire Hazard by Land Properties and Cloud to Ground Lightning Data with Association Rule Mining in Alberta, Canada

PubMed Central

Cha, DongHwan; Wang, Xin; Kim, Jeong Woo

2017-01-01

Hotspot analysis was implemented to find regions in the province of Alberta (Canada) with high frequency Cloud to Ground (CG) lightning strikes clustered together. Generally, hotspot regions are located in the central, central east, and south central regions of the study region. About 94% of annual lightning occurred during warm months (June to August) and the daily lightning frequency was influenced by the diurnal heating cycle. The association rule mining technique was used to investigate frequent CG lightning patterns, which were verified by similarity measurement to check the patterns’ consistency. The similarity coefficient values indicated that there were high correlations throughout the entire study period. Most wildfires (about 93%) in Alberta occurred in forests, wetland forests, and wetland shrub areas. It was also found that lightning and wildfires occur in two distinct areas: frequent wildfire regions with a high frequency of lightning, and frequent wild-fire regions with a low frequency of lightning. Further, the preference index (PI) revealed locations where the wildfires occurred more frequently than in other class regions. The wildfire hazard area was estimated with the CG lightning hazard map and specific land use types. PMID:29065564

Assessing Lightning and Wildfire Hazard by Land Properties and Cloud to Ground Lightning Data with Association Rule Mining in Alberta, Canada.

PubMed

Cha, DongHwan; Wang, Xin; Kim, Jeong Woo

2017-10-23

Hotspot analysis was implemented to find regions in the province of Alberta (Canada) with high frequency Cloud to Ground (CG) lightning strikes clustered together. Generally, hotspot regions are located in the central, central east, and south central regions of the study region. About 94% of annual lightning occurred during warm months (June to August) and the daily lightning frequency was influenced by the diurnal heating cycle. The association rule mining technique was used to investigate frequent CG lightning patterns, which were verified by similarity measurement to check the patterns' consistency. The similarity coefficient values indicated that there were high correlations throughout the entire study period. Most wildfires (about 93%) in Alberta occurred in forests, wetland forests, and wetland shrub areas. It was also found that lightning and wildfires occur in two distinct areas: frequent wildfire regions with a high frequency of lightning, and frequent wild-fire regions with a low frequency of lightning. Further, the preference index (PI) revealed locations where the wildfires occurred more frequently than in other class regions. The wildfire hazard area was estimated with the CG lightning hazard map and specific land use types.

40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Quality Control Region. 81.104 Section 81.104 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality Control Region consists of the territorial area encompassed by...

40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Quality Control Region. 81.104 Section 81.104 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality Control Region consists of the territorial area encompassed by...

Central Appalachia in advanced capitalism: its coal industry structure and coal operator associations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walls, D.S.

1978-01-01

This study traces the origins of the notion that Appalachia constitutes a unique social-problem region, examines the models of Appalachian problems popularized during the 1960s, proposes an alternative framework for situating the Central Appalachian coalfields, and examines aspects of the coal industry's structure in the Central Appalachian region. The idea of Appalachia as a distinctive social problem region was created between 1890 and 1930 by a social movement affiliated with various Protestant church home mission boards and organizationally focused in the Conference of Southern Mountain Workers and Berea College. The movement stressed an environmental explanation of regional problems. During themore » 1960s, three explanatory models of Appalachian poverty and underdevelopment achieved prominence: the subculture of poverty model, the regional development model, and the internal colonialism model. Each contributed to a regionalized conception of Appalachian problems. Empirical studies show the subculture of poverty model to fail as an explanation of regional underdevelopment. In the absence of a critique of domination and a redistribution of power and wealth, the regional development model serves as a rationalization of existing structures of privilege. The internal colonialism model provides a critique of domination, but not the most appropriate one. This study argues that the above models should not be viewed as mutually exclusive formulations, and that they may be reconstructed to represent different dimensions of social existence.« less

Distribution and time course of hair cell regeneration in the pigeon utricle

NASA Technical Reports Server (NTRS)

Dye, B. J.; Frank, T. C.; Newlands, S. D.; Dickman, J. D.

1999-01-01

Vestibular and cochlear regeneration following ototoxic insult from aminoglycoside antibiotics has been well documented, particularly in birds. In the present study, intraotic application of a 2 mg streptomycin paste was used to achieve complete vestibular hair cell destruction in pigeons (Columba livia) while preserving regenerative ability. Scanning electron microscopy was used to quantify hair cell density longitudinally during regeneration in three different utricular macula locations, including the striola, central and peripheral regions. The utricular epithelium was void of stereocilia (indicating hair cell loss) at 4 days after intraotic treatment with streptomycin. At 2 weeks the stereocilia began to appear randomly and mostly in an immature form. However, when present most kinocilia were polarized toward the developing striola. Initially, regeneration occurred more rapidly in the central and peripheral regions of the utricle as compared to the striola. As regeneration proceeded from 2 to 12 weeks, hair cell density in the striola region equaled the density noted in the central and peripheral regions. At 24 weeks, hair cell density of the central and peripheral regions was equal to normal values, however the striola region had a slightly greater hair cell density than that observed for normal animals.

Institutional Innovation and Public Extension Services Provision: The Marche Regional Administration Reform in Central Italy

ERIC Educational Resources Information Center

Pascucci, Stefano; De Magistris, Tiziana

2011-01-01

This paper describes how Marche Regional Administration (MRA) introduced an innovative institutional reform of an Agricultural Knowledge and Information System (AKIS) in central Italy. In order to study the main features of the MRA reform we used a methodological approach based on three steps: (i) first we applied a desk analysis to sketch the…

African American and Hispanic American sportsmen in the north central region

Treesearch

Allan Marsinko; John Dwyer

2003-01-01

Public forest managers need an awareness and understanding of their clients in order to better address their needs for recreational uses of forest lands. This study examines and characterizes African American and Hispanic American sportsmen (hunters and anglers) in the North Central Region of the United Stares (IA, IL, IN, MI, MN, MO, WI) and compares them to African...

Student Mobility in Rural and Nonrural Districts in Five Central Region States. Issues & Answers. REL 2010-No. 089

ERIC Educational Resources Information Center

Beesley, Andrea; Moore, Laurie; Gopalani, Sarah

2010-01-01

This report describes the extent and distribution of student mobility in five Central Region states. The study, which calculated student mobility percentages in each state and compared percentages by locale (city, suburb, town, and rural locale, and degree of rurality) within each state, found no consistent patterns across locales. Research…

Burnout and Associated Factors among Administrators/Mid-Managers of the Cooperative Extension Service in the North Central Region. Summary of Research 46.

ERIC Educational Resources Information Center

Clark, Richard Warner; Smith, Keith L.

A study was conducted to (1) determine the level of burnout, job satisfaction, personal strain, occupational stress, and personal coping resources of associate directors, assistant directors, and district supervisors of the Cooperative Extension Service in the North Central Region; (2) determine the extent of association between burnout and…

High baryon and energy densities achievable in heavy-ion collisions at √{sN N}=39 GeV

NASA Astrophysics Data System (ADS)

Ivanov, Yu. B.; Soldatov, A. A.

2018-02-01

Baryon and energy densities, which are reached in central Au+Au collisions at collision energy of √{sN N}= 39 GeV, are estimated within the model of three-fluid dynamics. It is shown that the initial thermalized mean proper baryon and energy densities in a sizable central region approximately are nB/n0≈ 10 and ɛ ≈ 40 GeV/fm3, respectively. The study indicates that the deconfinement transition at the stage of interpenetration of colliding nuclei makes the system quite opaque. The final fragmentation regions in these collisions are formed not only by primordial fragmentation fireballs, i.e., the baryon-rich matter passed through the interaction region (containing approximately 30% of the total baryon charge), but also by the baryon-rich regions of the central fireball pushed out to peripheral rapidities by the subsequent almost one-dimensional expansion of the central fireball along the beam direction.

Regional differences in the psychological recovery of Christchurch residents following the 2010/2011 earthquakes: a longitudinal study.

PubMed

Greaves, Lara M; Milojev, Petar; Huang, Yanshu; Stronge, Samantha; Osborne, Danny; Bulbulia, Joseph; Grimshaw, Michael; Sibley, Chris G

2015-01-01

We examined changes in psychological distress experienced by residents of Christchurch following two catastrophic earthquakes in late 2010 and early 2011, using data from the New Zealand Attitudes and Values Study (NZAVS), a national probability panel study of New Zealand adults. Analyses focused on the 267 participants (172 women, 95 men) who were living in central Christchurch in 2009 (i.e., before the Christchurch earthquakes), and who also provided complete responses to our yearly panel questionnaire conducted in late 2010 (largely between the two major earthquakes), late 2011, and late 2012. Levels of psychological distress were similar across the different regions of central Christchurch immediately following the September 2010 earthquake, and remained comparable across regions in 2011. By late 2012, however, average levels of psychological distress in the regions had diverged as a function of the amount of property damage experienced within each given region. Specifically, participants in the least damaged region (i.e., the Fendalton-Waimairi and Riccarton-Wigram wards) experienced greater drops in psychological distress than did those in the moderately damaged region (i.e., across the Spreydon-Heathcote and Hagley-Ferrymead wards). However, the level of psychological distress reported by participants in the most damaged region (i.e., across Shirley-Papanui and Burwood-Pegasus) were not significantly different to those in the least damaged region of central Christchurch. These findings suggest that different patterns of psychological recovery emerged across the different regions of Christchurch, with the moderately damaged region faring the worst, but only after the initial shock of the destruction had passed.

Regional Differences in the Psychological Recovery of Christchurch Residents Following the 2010/2011 Earthquakes: A Longitudinal Study

PubMed Central

Greaves, Lara M.; Milojev, Petar; Huang, Yanshu; Stronge, Samantha; Osborne, Danny; Bulbulia, Joseph; Grimshaw, Michael; Sibley, Chris G.

2015-01-01

We examined changes in psychological distress experienced by residents of Christchurch following two catastrophic earthquakes in late 2010 and early 2011, using data from the New Zealand Attitudes and Values Study (NZAVS), a national probability panel study of New Zealand adults. Analyses focused on the 267 participants (172 women, 95 men) who were living in central Christchurch in 2009 (i.e., before the Christchurch earthquakes), and who also provided complete responses to our yearly panel questionnaire conducted in late 2010 (largely between the two major earthquakes), late 2011, and late 2012. Levels of psychological distress were similar across the different regions of central Christchurch immediately following the September 2010 earthquake, and remained comparable across regions in 2011. By late 2012, however, average levels of psychological distress in the regions had diverged as a function of the amount of property damage experienced within each given region. Specifically, participants in the least damaged region (i.e., the Fendalton-Waimairi and Riccarton-Wigram wards) experienced greater drops in psychological distress than did those in the moderately damaged region (i.e., across the Spreydon-Heathcote and Hagley-Ferrymead wards). However, the level of psychological distress reported by participants in the most damaged region (i.e., across Shirley-Papanui and Burwood-Pegasus) were not significantly different to those in the least damaged region of central Christchurch. These findings suggest that different patterns of psychological recovery emerged across the different regions of Christchurch, with the moderately damaged region faring the worst, but only after the initial shock of the destruction had passed. PMID:25932919

Research on trend of warm-humid climate in Central Asia

NASA Astrophysics Data System (ADS)

Gong, Zhi; Peng, Dailiang; Wen, Jingyi; Cai, Zhanqing; Wang, Tiantian; Hu, Yuekai; Ma, Yaxin; Xu, Junfeng

2017-07-01

Central Asia is a typical arid area, which is sensitive and vulnerable part of climate changes, at the same time, Central Asia is the Silk Road Economic Belt of the core district, the warm-humid climate change will affect the production and economic development of neighboring countries. The average annual precipitation, average anneal temperature and evapotranspiration are the important indexes to weigh the climate change. In this paper, the annual precipitation, annual average temperature and evapotranspiration data of every pixel point in Central Asia are analyzed by using long-time series remote sensing data to analyze the trend of warm and humid conditions. Finally, using the model to analyzed the distribution of warm-dry trend, the warm-wet trend, the cold-dry trend and the cold-wet trend in Central Asia and Xinjiang area. The results showed that most of the regions of Central Asia were warm-humid and warm-dry trends, but only a small number of regions showed warm-dry and cold-dry trends. It is of great significance to study the climatic change discipline and guarantee the ecological safety and improve the ability to cope with climate change in the region. It also provide scientific basis for the formulation of regional climate change program. The first section in your paper

Population structure and relatedness among female Northern Pintails in three California wintering regions

USGS Publications Warehouse

Fleskes, Joseph P.; Fowler, Ada C.; Casazza, Michael L.; Eadie, John M.

2010-01-01

Female Northern Pintails (Anas acuta) were sampled in California's three main Central Valley wintering regions (Sacramento Valley, Suisun Marsh, San Joaquin Valley) during September–October before most regional movements occur and microsatellite and mitochondrial DNA were analyzed to examine population structure and relatedness. Despite reportedly high rates of early-fall pairing and regional fidelity, both sets of markers indicated that there was little overall genetic structuring by region. Pintails from Suisun Marsh did exhibit higher relatedness among individuals and capture groups than in the Sacramento or San Joaquin Valleys, likely reflecting a sample comprised of a greater proportion of local breeders. The lack of genetic structuring among regions indicates that a high degree of movement and interchange occurs among pintails wintering in the Central Valley. Thus, although maintaining the existing distribution of pintails among Central Valley regions is important for other reasons, it does not appear to be critical to retain current patterns of population genetic variation. Because of potential lack of independence among highly related study individuals, researchers should consider regional differences in relatedness when designing sampling schemes and interpreting research findings.

An Evaluation of Science Teacher Candidates' Energy Saving Behavior Intention Based on the Theory of Planned Behaviour

ERIC Educational Resources Information Center

Yüzüak, Ahmet Volkan; Erten, Sinan

2018-01-01

Aim of the study is to evaluate science teacher candidates' behaviour of energy saving intention among sustainable behaviours within the frame of the Theory of Planned Behaviour. The study was conducted with 1947 teacher candidates studying in six geographical regions of Turkey (Central Anatolia Region, Black Sea Region, Aegean Region, Marmara…

40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...

40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...

40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...

40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...

40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...

External Review Teams Training in Central America

ERIC Educational Resources Information Center

Silva-Trivino; Moises; Ramirez-Gatica, Soledad

2004-01-01

Many Latin American countries have started actions to promote a higher education quality assurance system. Central America appears as a regional effort that includes universities from all seven countries under the initiative of Central American University Higher Council (CSUCA). After focusing in quality management and self-study processes, CSUCA…

40 CFR 81.219 - Central Oregon Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Oregon Intrastate Air Quality... Quality Control Regions § 81.219 Central Oregon Intrastate Air Quality Control Region. The Central Oregon... outermost boundaries of the area so delimited): In the State of Oregon: Crook County, Deschutes County, Hood...

40 CFR 81.219 - Central Oregon Intrastate Air Quality Control Region.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Central Oregon Intrastate Air Quality... Quality Control Regions § 81.219 Central Oregon Intrastate Air Quality Control Region. The Central Oregon... outermost boundaries of the area so delimited): In the State of Oregon: Crook County, Deschutes County, Hood...

40 CFR 81.219 - Central Oregon Intrastate Air Quality Control Region.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Central Oregon Intrastate Air Quality... Quality Control Regions § 81.219 Central Oregon Intrastate Air Quality Control Region. The Central Oregon... outermost boundaries of the area so delimited): In the State of Oregon: Crook County, Deschutes County, Hood...

40 CFR 81.219 - Central Oregon Intrastate Air Quality Control Region.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Central Oregon Intrastate Air Quality... Quality Control Regions § 81.219 Central Oregon Intrastate Air Quality Control Region. The Central Oregon... outermost boundaries of the area so delimited): In the State of Oregon: Crook County, Deschutes County, Hood...

40 CFR 81.219 - Central Oregon Intrastate Air Quality Control Region.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Central Oregon Intrastate Air Quality... Quality Control Regions § 81.219 Central Oregon Intrastate Air Quality Control Region. The Central Oregon... outermost boundaries of the area so delimited): In the State of Oregon: Crook County, Deschutes County, Hood...

Demography of the Early Neolithic Population in Central Balkans: Population Dynamics Reconstruction Using Summed Radiocarbon Probability Distributions

PubMed Central

2016-01-01

The Central Balkans region is of great importance for understanding the spread of the Neolithic in Europe but the Early Neolithic population dynamics of the region is unknown. In this study we apply the method of summed calibrated probability distributions to a set of published radiocarbon dates from the Republic of Serbia in order to reconstruct population dynamics in the Early Neolithic in this part of the Central Balkans. The results indicate that there was a significant population growth after ~6200 calBC, when the Neolithic was introduced into the region, followed by a bust at the end of the Early Neolithic phase (~5400 calBC). These results are broadly consistent with the predictions of the Neolithic Demographic Transition theory and the patterns of population booms and busts detected in other regions of Europe. These results suggest that the cultural process that underlies the patterns observed in Central and Western Europe was also in operation in the Central Balkan Neolithic and that the population increase component of this process can be considered as an important factor for the spread of the Neolithic as envisioned in the demic diffusion hypothesis. PMID:27508413

Identification and classification of hubs in brain networks.

PubMed

Sporns, Olaf; Honey, Christopher J; Kötter, Rolf

2007-10-17

Brain regions in the mammalian cerebral cortex are linked by a complex network of fiber bundles. These inter-regional networks have previously been analyzed in terms of their node degree, structural motif, path length and clustering coefficient distributions. In this paper we focus on the identification and classification of hub regions, which are thought to play pivotal roles in the coordination of information flow. We identify hubs and characterize their network contributions by examining motif fingerprints and centrality indices for all regions within the cerebral cortices of both the cat and the macaque. Motif fingerprints capture the statistics of local connection patterns, while measures of centrality identify regions that lie on many of the shortest paths between parts of the network. Within both cat and macaque networks, we find that a combination of degree, motif participation, betweenness centrality and closeness centrality allows for reliable identification of hub regions, many of which have previously been functionally classified as polysensory or multimodal. We then classify hubs as either provincial (intra-cluster) hubs or connector (inter-cluster) hubs, and proceed to show that lesioning hubs of each type from the network produces opposite effects on the small-world index. Our study presents an approach to the identification and classification of putative hub regions in brain networks on the basis of multiple network attributes and charts potential links between the structural embedding of such regions and their functional roles.

Early Intervention for At-Risk Children in the North Central Region: A Comparative Analysis of Selected State Education Agencies' Policies.

ERIC Educational Resources Information Center

Kunesh, Linda G.

The primary purpose of this policy study was to identify and examine early intervention policies for young children at risk of academic failure in selected state education agencies (SEAs) in the North Central Region of the United States. The secondary purpose was to document the processes by which the selected states in the north central…

A Comparative Economic Analysis of North-Central New Mexico. New Mexico Agricultural Experiment Station Research Report 211.

ERIC Educational Resources Information Center

Carruthers, Garrey E.; Eastman, Clyde

North-Central New Mexico has many of the problems common to other rural areas. Unemployment and underemployment rates tend to be high and per capita income relatively low. This study evaluated regional economic performance over a 19-year period (1949-1968) as compared to other regions and the nation. Shift analysis (a means of examining regional…

Active cycling of organic carbon in the central Arctic Ocean

NASA Astrophysics Data System (ADS)

Wheeler, Patricia A.; Gosselin, Michel; Sherr, Evelyn; Thibaultc, Delphine; Kirchman, David L.; Benner, Ronald; Whitledge, Terry E.

1996-04-01

THE notion of a barren central Arctic Ocean has been accepted since English's pioneering work1 on drifting ice-islands. The year-round presence of ice, a short photosynthetic season and low temperatures were thought to severely limit biological production1,2, although the paucity of data was often noted. Because primary production appeared to be low1,2, subsequent studies assumed that most organic carbon was either derived from river inputs or imported from adjacent continental-shelf regions3,4. Here we present shipboard measurements of biological produc-tion, biomass and organic carbon standing-stocks made during a cruise through the ice covering the central Arctic Ocean. Our results indicate that the central Arctic region is not a biological desert. Although it is less productive than oligotrophic ocean regions not covered by ice, it supports an active biological community which contributes to the cycling of organic carbon through dissolved and particulate pools.

Retinopathy of prematurity: the high cost of screening regional and remote infants.

PubMed

Yu, Tzu-Ying; Donovan, Tim; Armfield, Nigel; Gole, Glen A

2018-01-25

Demand for retinopathy of prematurity (ROP) screening is increasing for infants born at rural and regional hospitals where the service is not generally available. The health system cost for screening regional/remote infants has not been reported. The objective of this study is to evaluate the cost of ROP screening at a large centralized tertiary neonatal service for infants from regional/rural hospitals. This is a retrospective study to establish the cost of transferring regional/rural infants to the Royal Brisbane and Women's Hospital for ROP screening over a 28-month period. A total of 131 infants were included in this study. Individual infant costs were calculated from analysis of clinical and administrative records. Economic cost of ROP screening for all transfers from regional/rural hospitals to Royal Brisbane and Women's Hospital. The average economic cost of ROP screening for this cohort was AUD$5110 per infant screened and the total cost was AUD$669 413. The average cost per infant screened was highest for infants from a regional centre with a population of 75 000 (AUD$14 856 per child), which was also geographically furthest from Brisbane. No infant in this cohort transferred from a regional nursery reached criteria for intervention for ROP by standard guidelines. Health system costs for ROP screening of remote infants at a centralized hospital are high. Alternative strategies using telemedicine can now be compared with centralized screening. © 2018 Royal Australian and New Zealand College of Ophthalmologists.

Decreased centrality of cortical volume covariance networks in autism spectrum disorders.

PubMed

Balardin, Joana Bisol; Comfort, William Edgar; Daly, Eileen; Murphy, Clodagh; Andrews, Derek; Murphy, Declan G M; Ecker, Christine; Sato, João Ricardo

2015-10-01

Autism spectrum disorders (ASD) are a group of neurodevelopmental conditions characterized by atypical structural and functional brain connectivity. Complex network analysis has been mainly used to describe altered network-level organization for functional systems and white matter tracts in ASD. However, atypical functional and structural connectivity are likely to be also linked to abnormal development of the correlated structure of cortical gray matter. Such covariations of gray matter are particularly well suited to the investigation of the complex cortical pathology of ASD, which is not confined to isolated brain regions but instead acts at the systems level. In this study, we examined network centrality properties of gray matter networks in adults with ASD (n = 84) and neurotypical controls (n = 84) using graph theoretical analysis. We derived a structural covariance network for each group using interregional correlation matrices of cortical volumes extracted from a surface-based parcellation scheme containing 68 cortical regions. Differences between groups in closeness network centrality measures were evaluated using permutation testing. We identified several brain regions in the medial frontal, parietal and temporo-occipital cortices with reductions in closeness centrality in ASD compared to controls. We also found an association between an increased number of autistic traits and reduced centrality of visual nodes in neurotypicals. Our study shows that ASD are accompanied by atypical organization of structural covariance networks by means of a decreased centrality of regions relevant for social and sensorimotor processing. These findings provide further evidence for the altered network-level connectivity model of ASD. Copyright © 2015 Elsevier Ltd. All rights reserved.

Multi-tier drugs assessment in a decentralised health care system. The Italian case-study.

PubMed

Jommi, Claudio; Costa, Enrico; Michelon, Alessandra; Pisacane, Maria; Scroccaro, Giovanna

2013-10-01

To investigate the organisation and decision-making processes of regional and local therapeutic committees in Italy, as a case-study of decentralised health care systems. A structured questionnaire was designed, validated, and self-administered to respondents. Committee members, prioritisation, assessment process and criteria, and transparency of committees were investigated. The respondents represent 100% of the 17 regional committees out of 21 regions (in 4 regions there is not any regional formulary), 88% of the 16 hospital networks and 42% of the 183 public hospitals. The assessment process appears fragmented and may take a long time: drugs inclusion into hospital formularies requires two steps in most regions (regional and local assessment). Most of the therapeutic committees are closed to industry and patients associations involvement. Prioritisation in the assessment is mostly driven by disease severity, clinical evidence, and the absence of therapeutic alternatives. Only 13 out of the 17 regional committees have a public application form for drugs inclusion into regional formulary. Regional and local committees (i) often re-assess the clinical evidence already evaluated at central level and (ii) mostly rely on comparative drug unit prices per DDD and drug budget impact. The level of transparency is quite low. The Italian case-study provides useful insights into an appropriate management of multi-tier drugs assessment, which is particularly complex in decentralised health care systems, but exists also in centralised systems where drugs are assessed by local therapeutic committees. A clear definition of regulatory competences at different levels, a higher collaboration between central, regional and local actors, and increased transparency are necessary to pursue consistency between central policies on price and reimbursement and budget accountability at the regional and local levels. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

East and central farming and forest region and Atlantic basin diversified farming region: LRRs N and S

Treesearch

Brad D. Lee; John M. Kabrick

2017-01-01

The central, unglaciated US east of the Great Plains to the Atlantic coast corresponds to the area covered by LRR N (East and Central Farming and Forest Region) and S (Atlantic Basin Diversified Farming Region). These regions roughly correspond to the Interior Highlands, Interior Plains, Appalachian Highlands, and the Northern Coastal Plains.

Antibodies in sera from camels (Camelus dromedarius) in western and sothren regions of Central Province, Saudi Arabia.

PubMed

Al-Anazi, Abdullah D

2012-12-01

The study evaluated the seroprevalence of Toxoplasma gondii in domestic camels in Western and Southern regions of Central province of Saudi Arabia. In total, 713 serum samples from clinically healthy camels were analyzed for anti-T. gondii antibodies using the Latex agglutination test (LAT). Antibodies to T. gondii were found in 94 (13.1%) camels. The number of seropositive in Al-Quwayiyah region (16.9%) was considerably higher than in other regions. However, the differences in seroprevalence between the 4 regions were not statistically significant (P >. 0.05). These results indicate that T. gondii antibodies are widespread in the camel populations and suggest that toxoplasmosis is a widely spread zoonotic infection this region.

Not sending the message: A low prevalence of strength-based exercise participation in rural and regional Central Queensland.

PubMed

Dalbo, Vincent J; Czerepusko, James B; Tucker, Patrick S; Kingsley, Michael I; Moon, Jordan R; Young, Kaelin; Scanlan, Aaron T

2015-10-01

The primary aim of this study was to determine the prevalence of current strength-based exercise in rural and regional populations of Central Queensland. The secondary aim was to examine the proportion of residents from various demographic groups who currently partake in strength-based exercise to allow for targeted strength training campaigns. A cross-sectional, survey-based experimental design was followed. Rural and regional Australia. Rural and regional community-dwelling individuals living in Central Queensland and aged 18 years and older. Survey data was collected in October and November 2010 as part of the Central Queensland University Social Survey. Strength-based exercise participation, gender, age, income, years of education, self-reported physical activity and perception of health. Participation in strength-based exercise was 13.2%. Women were less likely to partake in strength-based exercise than male, and ≥55 year old adults were less likely to partake in strength-based exercise than 18-34 year old adults. Participation in strength-based exercise was found to increase with years of education, self-reported physical activity and self-rated health. The prevalence of adults in rural and regional Central Queensland engaging in strength-based exercise is low. Exercise physiologists, clinicians and government officials must work together to ensure that this form of exercise is acknowledged as a vital component of health in rural and regional areas. © 2015 National Rural Health Alliance Inc.

Monitoring the Mesoamerican Biological Corridor: A NASA/CCAD Cooperative Research Project

NASA Technical Reports Server (NTRS)

Sever, Thomas; Irwin, Daniel; Sader, Steven A.; Saatchi, Sassan

2004-01-01

To foster scientific cooperation under a Memorandum of Understanding between NASA and the Central American countries, the research project developed regional databases to monitor forest condition and environmental change throughout the region. Of particular interest is the Mesoamerican Biological Corridor (MBC), a chain of protected areas and proposed conservation areas that will link segments of natural habitats in Central America from the borders of northern Columbia to southern Mexico. The first and second year of the project focused on the development of regional satellite databases (JERS-IC, MODIS, and Landsat-TM), training of Central American cooperators and forest cover and change analysis. The three regional satellite mosaics were developed and distributed on CD-ROM to cooperators and regional outlets. Four regional remote sensing training courses were conducted in 3 countries including participants from all 7 Central American countries and Mexico. In year 3, regional forest change assessment in reference to Mesoamerican Biological Corridor was completed and land cover maps (from Landsat TM) were developed for 7 Landsat scenes and accuracy assessed. These maps are being used to support validation of MODIS forest/non forest maps and to examine forest fragmentation and forest cover change in selected study sites. A no-cost time extension (2003-2004) allowed the completion of an M.S. thesis by a Costa Rican student and preparation of manuscripts for future submission to peer-reviewed outlets. Proposals initiated at the end of the project have generated external funding from the U.S. Forest Service (to U. Maine), NASA-ESSF (Oregon State U.) and from USAID and EPA (to NASA-MSFC-GHCC) to test MODIS capabilities to detect forest change; conduct literature review on biomass estimation and carbon stocks and develop a regional remote sensing monitoring center in Central America. The success of the project has led to continued cooperation between NASA, other federal agencies, and scientists from all seven Central American Countries (see SERVIR web site for this ongoing work - servir.nsstc.nasa.gov).

Arg25Pro polymorphism of transforming growth factor-beta1 and its role in the pathogenesis of essential hypertension in Russian population of the Central Chernozem Region.

PubMed

Ivanov, V P; Solodilova, M A; Polonnikov, A V; Belugin, D A; Shestakov, A M; Ushachev, D V; Khoroshaya, I V; Katargina, L N; Kozhukhov, M A; Kolesnikova, O E

2007-07-01

We studied the relationship between Arg25Pro polymorphism of TGFbeta1 gene and predisposition to essential hypertension in the Russian population of Central Chernozem Region (n=402). An association was found between 25Pro allele and 25ArgPro genotype with low risk of essential hypertension in male individuals.

Analysis of variables affecting unemployment rate and detecting for cluster in West Java, Central Java, and East Java in 2012

NASA Astrophysics Data System (ADS)

Samuel, Putra A.; Widyaningsih, Yekti; Lestari, Dian

2016-02-01

The objective of this study is modeling the Unemployment Rate (UR) in West Java, Central Java, and East Java, with rate of disease, infant mortality rate, educational level, population size, proportion of married people, and GDRP as the explanatory variables. Spatial factors are also considered in the modeling since the closer the distance, the higher the correlation. This study uses the secondary data from BPS (Badan Pusat Statistik). The data will be analyzed using Moran I test, to obtain the information about spatial dependence, and using Spatial Autoregressive modeling to obtain the information, which variables are significant affecting UR and how great the influence of the spatial factors. The result is, variables proportion of married people, rate of disease, and population size are related significantly to UR. In all three regions, the Hotspot of unemployed will also be detected districts/cities using Spatial Scan Statistics Method. The results are 22 districts/cities as a regional group with the highest unemployed (Most likely cluster) in the study area; 2 districts/cities as a regional group with the highest unemployed in West Java; 1 district/city as a regional groups with the highest unemployed in Central Java; 15 districts/cities as a regional group with the highest unemployed in East Java.

Active tectonics and strain partitioning along dextral fault system in Central Iran: Analysis of geomorphological observations and geophysical data in the Kashan region

NASA Astrophysics Data System (ADS)

Jamali, Farshad; Hessami, Khaled; Ghorashi, Manoochehr

2011-03-01

This paper uses high-resolution images and field investigations, in conjunction with seismic reflection data, to constrain active structural deformation in the Kashan region of Central Iran. Offset stream beds and Qanats indicate right-lateral strike slip motion at a rate of about 2 mm/yr along the NW-SE trending Qom-Zefreh fault zone which has long been recognized as one of the major faults in Central Iran. However, the pattern of drainage systems across the active growing folds including deep incision of stream beds and deflected streams indicate uplift at depth on thrust faults dipping SW beneath the anticlines. Therefore, our studies in the Kashan region indicate that deformation occurs within Central Iran which is often considered to behave as a non-deforming block within the Arabia-Eurasia collision zone. The fact that the active Qom-Zefreh strike-slip fault runs parallel to the active folds, which overlie blind thrust faults, suggests that oblique motion of Arabia with respect to Eurasia is partitioned in this part of Central Iran.

EXCESS CANCER MORTALITY IN AGRICULTURAL REGIONS OF MINNESOTA

EPA Science Inventory

Because of its unique geology, Minnesota can be divided into four agricultural regions: south-central region one (corn, soybeans); west-central region two (wheat, corn, soybeans); northwest region three (wheat, sugar beets, potatoes); and northeast region four (forested and urban...

The influence of land urbanization on landslides: An empirical estimation based on Chinese provincial panel data.

PubMed

Li, Gerui; Lei, Yalin; Yao, Huajun; Wu, Sanmang; Ge, Jianping

2017-10-01

This study used panel data for 28 provinces and municipalities in China from 2003 to 2014 to investigate the relationship between land urbanization and landslides by building panel models for a national sample and subsamples from the three regions of China and studied the problems of landslide prevention measures based on the relationship. The results showed that 1) at the national level, the percentage of built-up area and road density are respectively negative and positive for landslides. 2) At the regional level, the improvement of landslide prevention measures with increasing economic development only appears in built-up areas. The percentage of built-up areas increases the number of landslides in the western region and decreases the number in the central and eastern regions; the degree of decrease in the eastern region is larger than in the central region. Road density increases the number of landslides in each region, and the degree increases gradually from the west to the east. 3) The effect of landslide prevention funding is not obvious. Although the amount of landslide prevention funds decreases the number of landslides at the national level, the degree of increase is too small. Except in the central region, the amount of landslide prevention funding did not decrease the number of landslides effectively in the western and eastern regions. We propose a series of policy implications based on these test results that may help to improve landslide prevention measures. Copyright © 2017 Elsevier B.V. All rights reserved.

Functional network centrality in obesity: A resting-state and task fMRI study.

PubMed

García-García, Isabel; Jurado, María Ángeles; Garolera, Maite; Marqués-Iturria, Idoia; Horstmann, Annette; Segura, Bàrbara; Pueyo, Roser; Sender-Palacios, María José; Vernet-Vernet, Maria; Villringer, Arno; Junqué, Carme; Margulies, Daniel S; Neumann, Jane

2015-09-30

Obesity is associated with structural and functional alterations in brain areas that are often functionally distinct and anatomically distant. This suggests that obesity is associated with differences in functional connectivity of regions distributed across the brain. However, studies addressing whole brain functional connectivity in obesity remain scarce. Here, we compared voxel-wise degree centrality and eigenvector centrality between participants with obesity (n=20) and normal-weight controls (n=21). We analyzed resting state and task-related fMRI data acquired from the same individuals. Relative to normal-weight controls, participants with obesity exhibited reduced degree centrality in the right middle frontal gyrus in the resting-state condition. During the task fMRI condition, obese participants exhibited less degree centrality in the left middle frontal gyrus and the lateral occipital cortex along with reduced eigenvector centrality in the lateral occipital cortex and occipital pole. Our results highlight the central role of the middle frontal gyrus in the pathophysiology of obesity, a structure involved in several brain circuits signaling attention, executive functions and motor functions. Additionally, our analysis suggests the existence of task-dependent reduced centrality in occipital areas; regions with a role in perceptual processes and that are profoundly modulated by attention. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

[Central nervous system dysgerminoma: a clinicopathological study of 3 cases].

PubMed

Bellil, Selma; Braham, Emna; Limaiem, Faten; Bellil, Khadija; Chelly, Ines; Mekni, Amina; Haouet, Slim; Zitouna, Moncef; Jemel, Hafedh; Khaldi, Moncef; Kchir, Nidhameddine

2009-03-01

Intracranial germ cell tumors are rarely seen and typically localize in the pineal or suprasellar region. The largest category of germ cell tumors is dysgerminoma. to describe clinicopathological features and immunohistochemical profile of dysgerminomas. We report three cases of central nervous system dysgerminomas. There were two young women and a man who were 6, 11 and 23-year-old. They presented with symptoms of insipidus diabetes (n=3) with association to visual field defects in the third case. Radiological findings showed a supra seller lesion in two cases. Double localization in the pineal and suprasellar regions was seen in the third case. Histologic examination and immunohistochemical study of surgical specimen were consistent with primary central nervous system dysgerminoma.

Assessment of groundwater vulnerability in the coastal region of Oman using DRASTIC index method in GIS environment.

PubMed

Jamrah, Ahmad; Al-Futaisi, Ahmed; Rajmohan, Natarajan; Al-Yaroubi, Saif

2008-12-01

A study was carried out to develop a vulnerability map for Barka region in the North Batina of Oman using DRASTIC vulnerability index method in GIS environment. DRASTIC layers were created using data from published reports and the seven DRASTIC layers were processed by the ArcGIS geographic information system. Finally, DRASTIC maps were created for 1995 and 2004 to understand the long-term changes in the vulnerability index. DRASTIC vulnerability maps were evaluated using groundwater quality data such as chemical and biological parameters. DRASTIC vulnerability maps of 1995 and 2004 indicate that the northern part of Barka is more vulnerable to pollution than southern part and the central part of Barka also shows high relative vulnerability which is mostly related to the high conductivity values. Moreover, the changes in water level due to high abstraction rate of groundwater reflect in the vulnerability maps and low vulnerability area is increased in the southern part during 2004 compared to 1995. Moreover, regional distribution maps of nitrate, chloride and total and fecal coliforms are well correlated with DRASTIC vulnerability maps. In contrast to this, even though DRASTIC method predicted the central part of the study region is highly vulnerable, both chemical and biological parameters show lower concentrations in this region compared to coastal belt, which is mainly due to agricultural and urban development. In Barka, urban development and agricultural activities are very high in coastal region compared to southern and central part of the study area. Hence, this study concluded that DRASTIC method is also applicable in coastal region having ubiquitous contamination sources.

CYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome

PubMed Central

Mirzaev, Karin B; Zelenskaya, Elena M; Barbarash, Olga L; Ganyukov, Vladimir I; Apartsin, Konstantin A; Saraeva, Natalya O; Nikolaev, Konstantin Y; Ryzhikova, Kristina A; Lifshits, Galina I; Sychev, Dmitry A

2017-01-01

Purpose The aim of this study is to investigate the frequency of CYP2C19*2, *3 allelic variants, associated with poor response to clopidogrel, and CYP2C19*17, associated with excessive response to clopidogrel, in patients with acute coronary syndrome (ACS) from Siberia and Moscow regions of Russia. Patients and methods The study included 512 ACS patients who were subsequently treated with coronary arterial stenting. The subjects assigned were from the cities of Central (Novosibirsk, Kemerovo), Eastern (Irkutsk), Northern (Surgut) Siberia regions and from Moscow region. The mean age of patients enrolled was 63.9±10.9 years. Among the assigned subjects, the proportion of men accounted for 80% and women 20%. Results According to the results obtained in the present study, from 16% up to 27.5% of patients in different regions of Russia have at least one CYP2C19 “poor metabolizer” (PM) allele variant affecting clopidogrel metabolism and, therefore, suppressing its antiplatelet activity. CYP2C19*17 allele variant was identified with the frequency of 15.4% up to 33.3%. The study revealed the presence of statistically significant differences in CYP2C19*3 allele frequency between the Russian ethnic group patients from Eastern and Central Siberia (p=0.001; odds ratio=1.05 [95% confidence interval 1.01–1.09]). Conclusion The study revealed statistically significant differences between the allele frequencies in Eastern and Central Siberia, which can probably be caused by a considerable number of Buryats inhabiting Eastern Siberia. PMID:28442925

Groundwater quality in the shallow aquifers of the Monterey Bay, Salinas Valley, and adjacent highland areas, Southern Coast Ranges, California

USGS Publications Warehouse

Burton, Carmen

2018-05-30

The Monterey-Salinas Shallow Aquifer study unit covers approximately 7,820 square kilometers (km2) in Santa Cruz, Monterey, and San Luis Obispo Counties in the Central Coast Hydrologic Region of California. The study unit was divided into four study areas—Santa Cruz, Pajaro Valley, Salinas Valley, and Highlands. More than 75 percent of the water used for drinking-water supply in the Central Coast Hydrologic Region of California is groundwater, and there are more than 8,000 well driller’s logs for domestic wells (California Department of Water Resources, 2013).

Groundwater Quality in the Shallow Aquifers of the Monterey Bay, Salinas Valley, and Adjacent Highland Areas, Southern Coast Ranges, California

USGS Publications Warehouse

Burton, Carmen

2018-05-30

The Monterey-Salinas Shallow Aquifer study unit covers approximately 7,820 square kilometers (km2) in Santa Cruz, Monterey, and San Luis Obispo Counties in the Central Coast Hydrologic Region of California. The study unit was divided into four study areas—Santa Cruz, Pajaro Valley, Salinas Valley, and Highlands. More than 75 percent of the water used for drinking-water supply in the Central Coast Hydrologic Region of California is groundwater, and there are more than 8,000 well driller’s logs for domestic wells (California Department of Water Resources, 2013).

Determining hydroclimatic extreme events over the south-central Andes

NASA Astrophysics Data System (ADS)

RamezaniZiarani, Maryam; Bookhagen, Bodo; Schmidt, Torsten; Wickert, Jens; de la Torre, Alejandro; Volkholz, Jan

2017-04-01

The south-central Andes in NW Argentina are characterized by a strong rainfall asymmetry. In the east-west direction exists one of the steepest rainfall gradients on Earth, resulting from the large topographic differences in this region. In addition, in the north-south direction the rainfall intensity varies as the climatic regime shifts from the tropical central Andes to the subtropical south-central Andes. In this study, we investigate hydroclimatic extreme events over the south-central Andes using ERA-Interim reanalysis data of the ECMWF (European Centre for Medium-Range Weather Forecasts), the high resolution regional climate model (COSMO-CLM) data and TRMM (Tropical Rainfall Measuring Mission) data. We divide the area in three different study regions based on elevation: The high-elevation Altiplano-Puna plateau, an intermediate area characterized by intramontane basins, and the foreland area. We analyze the correlations between climatic variables, such as specific humidity, zonal wind component, meridional wind component and extreme rainfall events in all three domains. The results show that there is a high positive temporal correlation between extreme rainfall events (90th and 99th percentile rainfall) and extreme specific humidity events (90th and 99th percentile specific humidity). In addition, the temporal variations analysis represents a trend of increasing specific humidity with time during time period (1994-2013) over the Altiplano-Puna plateau which is in agreement with rainfall trend. Regarding zonal winds, our results indicate that 99th percentile rainfall events over the Altiplano-Puna plateau coincide temporally with strong easterly winds from intermountain and foreland regions in the east. In addition, the results regarding the meridional wind component represent strong northerly winds in the foreland region coincide temporally with 99th percentile rainfall over the Altiplano-Puna plateau.

Estructura, Cinemática y Condiciones Físicas del Merger NGC3256

NASA Astrophysics Data System (ADS)

Lípari, S.; Díaz, R. J.; Carranza, G.

We studied in detail the structure, the kinematics, and the physical conditions in the nuclear, central and external regions of the nearby merger and luminous IR source NGC 3256 (LIR = 3.3 × 1011Lsolar). Using broad-- (B, V, I) and narrow--band (Hα, [OIII]λ5007) images --obtained at ESO-NTT and CASLEO during march'89 to july'97-- we studied the properties of the main structures in this merger. In particular, we analyzed in detail the giant HII regions which are extended in the nuclear and central region of NGC 3256 and are probably associated to a massive starburst originated in the merger process of two gas rich spirals galaxies.

Radon Concentration in Groundwater in the Central Region of Gyeongju, Korea - 13130

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Jung Min; Lee, A. Rim; Park, Chan Hee

Radon is a naturally occurring radioactive gas that is a well known cause of lung cancer through inhalation. Nevertheless, stomach cancer can also occur if radon-containing water is ingested. This study measured the radon concentration in groundwater for drinking or other domestic uses in the central region of Gyeongju, Korea. The groundwater samples were taken from 11 points chosen from the 11 administrative districts in the central region of Gyeongju by selecting a point per district considering the demographic distribution including the number of tourists who visit the ancient ruins and archaeological sites. The mean radon concentrations in the groundwatermore » samples ranged from 14.38 to 9050.73 Bq.m{sup -3}, which were below the recommendations by the U.S. EPA and WHO. (authors)« less

Innovative Approaches to Collaborative Groundwater Governance in the United States: Case Studies from Three High-Growth Regions in the Sun Belt.

PubMed

Megdal, Sharon B; Gerlak, Andrea K; Huang, Ling-Yee; Delano, Nathaniel; Varady, Robert G; Petersen-Perlman, Jacob D

2017-05-01

Groundwater is an increasingly important source of freshwater, especially where surface water resources are fully or over-allocated or becoming less reliable due to climate change. Groundwater reliance has created new challenges for sustainable management. This article examines how regional groundwater users coordinate and collaborate to manage shared groundwater resources, including attention to what drives collaboration. To identify and illustrate these facets, this article examines three geographically diverse cases of groundwater governance and management from the United States Sun Belt: Orange County Water District in southern California; Prescott Active Management Area in north-central Arizona; and the Central Florida Water Initiative in central Florida. These regions have different surface water laws, groundwater allocation and management laws and regulations, demographics, economics, topographies, and climate. These cases were selected because the Sun Belt faces similar pressures on groundwater due to historical and projected population growth and limited availability of usable surface water supplies. Collectively, they demonstrate groundwater governance trends in the United States, and illustrate distinctive features of regional groundwater management strategies. Our research shows how geophysical realities and state-level legislation have enabled and/or stimulated regions to develop groundwater management plans and strategies to address the specific issues associated with their groundwater resources. We find that litigation involvement and avoidance, along with the need to finance projects, are additional drivers of regional collaboration to manage groundwater. This case study underscores the importance of regionally coordinated and sustained efforts to address serious groundwater utilization challenges faced by the regions studied and around the world.

Innovative Approaches to Collaborative Groundwater Governance in the United States: Case Studies from Three High-Growth Regions in the Sun Belt

NASA Astrophysics Data System (ADS)

Megdal, Sharon B.; Gerlak, Andrea K.; Huang, Ling-Yee; Delano, Nathaniel; Varady, Robert G.; Petersen-Perlman, Jacob D.

2017-05-01

Groundwater is an increasingly important source of freshwater, especially where surface water resources are fully or over-allocated or becoming less reliable due to climate change. Groundwater reliance has created new challenges for sustainable management. This article examines how regional groundwater users coordinate and collaborate to manage shared groundwater resources, including attention to what drives collaboration. To identify and illustrate these facets, this article examines three geographically diverse cases of groundwater governance and management from the United States Sun Belt: Orange County Water District in southern California; Prescott Active Management Area in north-central Arizona; and the Central Florida Water Initiative in central Florida. These regions have different surface water laws, groundwater allocation and management laws and regulations, demographics, economics, topographies, and climate. These cases were selected because the Sun Belt faces similar pressures on groundwater due to historical and projected population growth and limited availability of usable surface water supplies. Collectively, they demonstrate groundwater governance trends in the United States, and illustrate distinctive features of regional groundwater management strategies. Our research shows how geophysical realities and state-level legislation have enabled and/or stimulated regions to develop groundwater management plans and strategies to address the specific issues associated with their groundwater resources. We find that litigation involvement and avoidance, along with the need to finance projects, are additional drivers of regional collaboration to manage groundwater. This case study underscores the importance of regionally coordinated and sustained efforts to address serious groundwater utilization challenges faced by the regions studied and around the world.

Canadian forest products shipped into the north-central region.

Treesearch

Eugene M. Carpenter

1972-01-01

Documents the imports of Canadian forest products into the north central region and relates import trends to the potential for expanding markets for the region's surplus volume of hardwood growing stock. More than 42% of the $2.1 billion of forest products imported from Canada in 1969 came into the north central region. The value of forest imports has increased...

SKS splitting results in central Italy and Dinaric region inside the AlpArray-CASE project

NASA Astrophysics Data System (ADS)

Salimbeni, S.; Prevolnik, S.; Pondrelli, S.; Molinari, I.; Stipcevic, J.; Kissling, E.; Šipka, V.; Herak, M.

2017-12-01

In the framework of the AlpArray project (AlpArray Seismic Network, 2015), the complementary "Central Adriatic Seismic Experiment" (CASE; AlpArray Seismic Network, 2016) was established as collaboration between ETH Zürich, University of Zagreb, INGV and Republic Hydrometeorological Service of Republic of Srpska. The CASE project consists of 9 temporary stations, installed in October 2016, located in Bosnia and Herzegovina, Croatia and Italy. Temporary broadband seismic stations, with the permanent stations present in the region shared by the Croatian Seismological Service and INGV, make an almost continuous transect cutting the Central-Southern Appenines, the central Adriatic region, central External Dinarides and finishing at the eastern margin of the Internal Dinarides. The presence of the the Apenninic and Dinarides slabs, verging in opposite directions and plunging along the opposite sides of the Adriatic plate, make this area a peculiar spot to understand the complex dynamic of the region. Various tomographic images (e.g. Bijwaard and Spakman, 2000; Piromallo and Morelli, 2003) shows not continuous slabs under the Appenines and the Dinarides, suggesting the presence of slab-gaps right beneath the region covered by the CASE experiment. Here we present the preliminary results of the SKS splitting analysis performed on the data recorded by the temporary and permanent seismic stations included in the CASE project. The new results, in combination with previous interpretation, will provide clues about how Northern and Southern Apennines are connected at depth, how the slab rollback of the Apennines thrust belt acted and if and how the Apennines are in relation with the Dinaric region. Together with the measurements from previous studies and from the AlpArray project, our new data will support the mapping of the seismic anisotropy deformation pattern from Western Alps to Pannonian region.

Effect of anthropogenic sulphate aerosol in China on the drought in the western-to-central US

NASA Astrophysics Data System (ADS)

Yeh, Sang-Wook; Park, Rokjin J.; Kim, Minjoong J.; Jeong, Jaein I.; Song, Chang-Keun

2015-09-01

In recent decades, droughts have occurred in the western-to-central United States (US), significantly affecting food production, water supplies, ecosystem health, and the propagation of vector-borne diseases. Previous studies have suggested natural sea surface temperature (SST) forcing in the Pacific as the main driver of precipitation deficits in the US. Here, we show that the aerosol forcing in China, which has been known to alter the regional hydrological cycle in East Asia, may also contribute to reducing the precipitation in the western-to-central US through atmospheric teleconnections across the Pacific. Our model experiments show some indications that both the SST forcing and the increase in regional sulphate forcing in China play a similar role in modulating the western-to-central US precipitation, especially its long-term variation. This result indicates that regional air quality regulations in China have important implications for hydrological cycles in East Asia, as well as in the US.

Exercise-related alterations in crimp morphology in the central regions of superficial digital flexor tendons from young thoroughbreds: a controlled study.

PubMed

Patterson-Kane, J C; Wilson, A M; Firth, E C; Parry, D A; Goodship, A E

1998-01-01

Injury to the core of the mid-metacarpal region of the superficial digital flexor tendon in Thoroughbred racehorses is a very frequent but poorly understood condition. It has been suggested that subclinical changes induced by galloping exercise weaken the collagen in this region of the tendon, predisposing it to rupture. The longitudinally arranged collagen fibrils in tendon follow a planar waveform, termed the crimp. Fibril bundles with a smaller crimp angle fail at a lower level of strain than those with a larger crimp angle. This study tested the hypothesis that a specific 18 month exercise programme would result in significant reduction of collagen fibril crimp angle and period length in the core region of the superficial digital flexor tendon of young Thoroughbreds (21 +/- 1 months), compared to the normal change in these parameters with age. Central region crimp angle and length were significantly lower in exercised horses than in control horses (P < 0.05). The crimp angle was significantly lower in this central region than in the peripheral region of the tendon in 4 of the 5 exercised horses, as was the crimp length in 3 of the 4 horses. The crimp angle in the peripheral region was significantly greater in exercised horses than in the controls (P < 0.05), which may indicate functional adaptation due to differing mechanical environment between the 2 tendon regions. The results of this study supported previous evidence that galloping exercise modifies normal age-related changes in crimp morphology in the core of the superficial digital flexor tendon. Such changes are indicative of microtrauma and would be detrimental to tendon strength.

Forest soils bibliography for the North-Central Region (including subject matter index through 1972).

Treesearch

Willard H. Carmean

1973-01-01

Includes 793 publications dealing with forest soils in the North-Central States (Minnesota, Wisconsin, Michigan, Iowa, Missouri, Illinois, and Indiana); Ohio; and the Northern Plains States (Kansas, Nebraska, and the Dakotas). Includes some publications from other regions considered applicable to conditions in the North-Central Region.

The Central Hardwood Forest: its boundaries and physiographic provinces

Treesearch

James S. Fralish

2003-01-01

The Central Hardwood Forest (CHF) refers to the area where deciduous hardwood species overwhelmingly, but not exclusively, dominate the stands and cover types that occur as repeating units across the landscape. Transition zones where Central Hardwood species mix with species from adjacent regions identify boundaries of the region. These regions are the Northern...

The Central Hardwood Forest: Its Boundaries and Physiographic Provinces

Treesearch

James S. Fralish

2003-01-01

The Central Hardwood Forest (CHF) refers to the area where deciduous hardwood species overwhelmingly, but not exclusively, dominate the stands and cover types that occur as repeating units across the landscape. Transition zones where Central Hardwood species mix with species from adjacent regions identify boundaries of the region. These regions are the Northern...

Vegetation impoverishment despite greening: a case study from central Senegal

USGS Publications Warehouse

Herrmann, Stefanie M.; Tappan, G. Gray

2013-01-01

Recent remote sensing studies have documented a greening trend in the semi-arid Sahel and Sudan zones of West Africa since the early 1980s, which challenges the mainstream paradigm of irreversible land degradation in this region. What the greening trend means on the ground, however, has not yet been explored. This research focuses on a region in central Senegal to examine changes in woody vegetation abundance and composition in selected sites by means of a botanical inventory of woody vegetation species, repeat photography, and perceptions of local land users. Despite the greening, an impoverishment of the woody vegetation cover was observed in the studied sites, indicated by an overall reduction in woody species richness, a loss of large trees, an increasing dominance of shrubs, and a shift towards more arid-tolerant, Sahelian species since 1983. Thus, interpretation of the satellite-derived greening trend as an improvement or recovery is not always justified. The case of central Senegal represents only one of several possible pathways of greening throughout the region, all of which result in similar satellite-derived greening signals.

Impacts of Central American Fires on Ozone Air Quality along the US Gulf Coast

NASA Astrophysics Data System (ADS)

Wang, S. C.; Wang, Y.; Estes, M. J.; Lei, R.; Talbot, R. W.

2017-12-01

Biomass burning in Central America is associated with agriculture activities and occurs regularly during April and May every year. Satellite observations have documented frequent transport of wildfire smoke from Mexico and Central America to the southern US, causing haze and exceedance of fine particle matter. However, the impacts of those fires on surface ozone in the US are poorly understood. This study uses both observations and modeling to examine the effects of the springtime Central America fire emissions on surface ozone over the Gulf coastal regions over a long-term time period (2002-2015). Passive tracer simulation in the nested-grid version of the GEOS-Chem chemical transport model over North America is used to identify the days when Central American fire plumes reached the US Gulf Coast. During the identified fire-impact days, Central American fires are estimated to result in an average of 9 ppbv enhancement of regional background ozone over the Houston-Galveston-Brazoria (HGB) region. Satellite-observed distributions of AOD and CO are used to examine the transport pathways and effects of those fires on atmospheric composition. Finally, we integrate satellite observations, ground measurements, and modeling to quantify the impact of Central American fires on springtime ozone air quality along the US Gulf Coast in terms of both long-term (2002-2015) mean and extreme cases.

Wildlife-associated recreation in the North Central Region: participation patterns and management implications

Treesearch

Allan Marsinko; John Dwyer

2002-01-01

The North Central Region (IA, IL, IN, MI, MN, MO, WI) is a diverse area of the United States. Compared to the remainder of the country, the region as a whole is demographically similar in terms of mean age, education, household income, and gender. However, the North Central region has a higher proportion of Whites and a slightly lower proportion of people residing in...

Nucleosome exclusion from the interspecies-conserved central AT-rich region of the Ars insulator.

PubMed

Takagi, Haruna; Inai, Yuta; Watanabe, Shun-ichiro; Tatemoto, Sayuri; Yajima, Mamiko; Akasaka, Koji; Yamamoto, Takashi; Sakamoto, Naoaki

2012-01-01

The Ars insulator is a boundary element identified in the upstream region of the arylsulfatase (HpArs) gene in the sea urchin, Hemicentrotus pulcherrimus, and possesses the ability to both block enhancer-promoter communications and protect transgenes from silent chromatin. To understand the molecular mechanism of the Ars insulator, we investigated the correlation between chromatin structure, DNA structure and insulator activity. Nuclease digestion of nuclei isolated from sea urchin embryos revealed the presence of a nuclease-hypersensitive site within the Ars insulator. Analysis of micrococcal nuclease-sensitive sites in the Ars insulator, reconstituted with nucleosomes, showed the exclusion of nucleosomes from the central AT-rich region. Furthermore, the central AT-rich region in naked DNA was sensitive to nucleotide base modification by diethylpyrocarbonate (DEPC). These observations suggest that non-B-DNA structures in the central AT-rich region may inhibit nucleosomal formation, which leads to nuclease hypersensitivity. Furthermore, comparison of nucleotide sequences between the HpArs gene and its ortholog in Strongylocentrotus purpuratus revealed that the central AT-rich region of the Ars insulator is conserved, and this conserved region showed significant enhancer blocking activity. These results suggest that the central AT-rich nucleosome-free region plays an important role in the function of the Ars insulator.

Low levels of arsenic in drinking water and type 2 diabetes in Middle Banat region, Serbia.

PubMed

Jovanovic, Dragana; Rasic-Milutinovic, Zorica; Paunovic, Katarina; Jakovljevic, Branko; Plavsic, Snezana; Milosevic, Jelena

2013-01-01

Arsenic in drinking water presents a serious public health problem in Serbia, but its relationship with diabetes has not been studied previously. The aim of this study was to explore the association between exposure to arsenic in drinking water and the occurrence of type 2 diabetes in Middle Banat region, Serbia. This cross-sectional study comprised two populations. Exposed population in Middle Banat region consumes drinking water with arsenic (mean = 56 μg/L); unexposed population from six regions in Central Serbia consumes arsenic below detection limit (2 μg/L). Newly diagnosed cases of type 2 diabetes were obtained from the National Registry of Diabetes in 2008. The Registry included age, gender, family history of diabetes, presence of overweight, central obesity, cholesterol and triglyceride levels. In addition, the number of cases of diabetes reported in years 2006, 2007 and 2009 was used to calculate standardized incidence rates for both populations. Two populations were comparable by age, family history of diabetes and prevalence of overweight persons. Unexposed population was more likely to have central obesity, and high total cholesterol and triglycerides. Standardized incidence rates of type 2 diabetes were higher in exposed population. Odds ratios for type 2 diabetes were significantly higher for the exposed population, both men and women, in the period from 2006 to 2009, when compared with the unexposed population. The population from Middle Banat region, consuming drinking water with low levels of arsenic, was at higher risk for the occurrence of type 2 diabetes in comparison to the unexposed population in Central Serbia. Copyright © 2012 Elsevier GmbH. All rights reserved.

Drought Vulnerability Mapping with Geomorphological Approach in Yogyakarta Special Region (DIY) and Central Java

NASA Astrophysics Data System (ADS)

Sudaryatno

2016-11-01

This study aims to determine the level of vulnerability of the geomorphologic drought that occurred in Central Java and Yogyakarta Special Region. This study examines geomorphologic drought. Parameters used were slope, drainage, Available Water Capacity (AWC), permeability, landform, and land use. Landsat 8 and SRTM data were used for the extraction of physical parameters, such as slope, drainage, landform, and land use. The method used in this study is scoring and weighting. Query results were used for data classification by overlaying drought geomorphologic parameters. The expected outcome of this research is to map the geomorphologic drought vulnerability on Central Java and Yogyakarta Special Region. Drought vulnerability was divided into wet, normal and dry classes. Distribution of the dry class is frequent. Some of the dry classes are distributed on the steep till extremely steep slope region and on the structural and karsts landform. This was related to AWC value where region with high AWC contributed to the poor drainage of the soil, such as at Kulonprogo, Purworejo, Kebumen, Blora, Wonogiri, Purbalingga, Pekalongan, Jepara and Kudus regency. Normal classes are distributed on the sloping till steep slope, have moderate till well-drained soil and low AWC, such as at Gunung Kidul, Pati, Temanggung regency, and Magelang city. Wet classes are distributed on the flat or almost flat and sloping region. Most of the wet classes are distributed on volcanic hills and coastal area. Those regions are well-drained and the land uses are mostly for settlement and farming, such as at Sleman, Yogyakarta city, Klaten, Bantul, and Wonosobo regency.

Possible existence of wormholes in the central regions of halos

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rahaman, Farook, E-mail: rahaman@iucaa.ernet.in; Salucci, P., E-mail: salucci@sissa.it; INFN, Sezione di Trieste, Via Valerio 2, 34127, Trieste

2014-11-15

An earlier study (Rahaman, et al., 2014 and Kuhfittig, 2014) has demonstrated the possible existence of wormholes in the outer regions of the galactic halo, based on the Navarro–Frenk–White (NFW) density profile. This paper uses the Universal Rotation Curve (URC) dark matter model to obtain analogous results for the central parts of the halo. This result is an important compliment to the earlier result, thereby confirming the possible existence of wormholes in most of the spiral galaxies. - Highlights: • Earlier we showed possible existence of wormholes in the outer regions of halo. • We obtain here analogous results for themore » central parts of the galactic halo. • Our result is an important compliment to the earlier result. • This confirms possible existence of wormholes in most of the spiral galaxies.« less

A histomorphometric study of adaptive responses of cancellous bone in different regions in the sheep mandibular condyle following experimental forward mandibular displacement.

PubMed

Ma, Bingkui; Sampson, Wayne; Wilson, David; Wiebkin, Ole; Fazzalari, Nicola

2002-07-01

Forward mandibular displacement in animal models is associated with faster and/or redirected condylar growth. Here the effect of forward displacement induced with an intraoral appliance on modelling/remodelling of the mandibular condyle was investigated in eight, 4-month-old, castrated male Merino sheep, randomly allocated to experimental and control groups (n=4 in each group). The study period was 15 weeks, during that time, (1). calcein, (2). tetracycline, and (3). alizarin red S fluorochromes were given to all animals from day 1. Midsagittal sections of the temporomandibular joints were selected for analysis. Dynamic variables of bone formation, static indices of bone-forming and -resorbing activity, and structural indices of trabecular bone were estimated histomorphometrically. The sampling site was divided into two regions for analysis: (a). a 'subchondral region' (2 and 3 labels only), believed to be the bone newly formed during the experimental period; (b). a 'central region' (labelled by all three fluorochromes), believed to be the bone that existed before the experiment. Regional differences in adaptive response were found. In the experimental group, the bone-volume fraction (BV/TV) of the subchondral regions had decreased, although the specific bone-surface and bone-formation rates had increased. This low BV/TV was associated with decreased trabecular thickness and increased trabecular separation. In the central condylar region of the experimental group, BV/TV was unchanged, but an increased osteoid surface was apparent when the eroded surface was taken into consideration. These adaptive condylar responses to forward mandibular displacement appeared to be the result of increased osteoblastic activity. Further studies are recommended to examine why the subchondral and central regions responded differently.

Association of tongue brushing with the number of fungiform taste buds and taste perception: A preliminary study using confocal laser scanning microscopy in combination with a filter-paper disc method.

PubMed

Kobayashi, Junichi; Saito, Takehisa; Ito, Tetsufumi; Yoshimura, Hitoshi; Matsuda, Shinpei; Yoshida, Hisato; Fujita, Ryousuke; Sano, Kazuo

2017-12-01

The aim of this study was to investigate the association of tongue brushing with the number of fungiform taste buds and taste perception using a confocal laser scanning microscopy in combination with a filter-paper disc method (FPDM). Twenty-four subjects with or without a habit of tongue brushing (11 males and 13 females, 20-46 years old) participated in this study. Nine of the 24 subjects had no habit of tongue brushing (Group 1, n=9). Fifteen subjects had a habit of tongue brushing, and the brushing regions of the tongue were as follows: central region (Group 2, n=7), or entire region (Group 3, n=8) of the tongue dorsum. Using confocal laser scanning microscopy, the average number of taste buds per fungiform papilla (FP) was counted. Taste perception was evaluated using an FPDM. These observations were performed in the midlateral region of the tongue since the distribution of fungiform papillae is large in the midlateral region compared to that in the central region. The subjects in Group 3 showed a significantly decreased number of fungiform taste buds compared to Group 1 and Group 2. Group 3 also showed significantly higher FPDM scores than the other two groups. Excessive tongue brushing of the entire tongue dorsum, including the midlateral region, may have an association with the decreased number of FP and taste buds and decreased taste sensation. To avoid these conditions, instituting proper tongue brushing methods, such as limiting it to the central region of the tongue and using a light touch, is suggested and is important for the subjects who are eager to participate in tongue brushing. Copyright © 2017 Elsevier Ltd. All rights reserved.

Impacts of Changing Climate on Agricultural Variability: Implications for Smallholder Farmers in India

NASA Astrophysics Data System (ADS)

Mondal, P.; Jain, M.; DeFries, R. S.; Galford, G. L.; Small, C.

2013-12-01

Agriculture is the largest employment sector in India, where food productivity, and thus food security, is highly dependent on seasonal rainfall and temperature. Projected increase in temperature, along with less frequent but intense rainfall events, will have a negative impact on crop productivity in India in the coming decades. These changes, along with continued ground water depletion, could have serious implications for Indian smallholder farmers, who are among some of the most vulnerable communities to climatic and economic changes. Hence baseline information on agricultural sensitivity to climate variability is important for strategies and policies that promote adaptation to climate variability. This study examines how cropping patterns in different agro-ecological zones in India respond to variations in precipitation and temperature. We specifically examine: a) which climate variables most influence crop cover for monsoon and winter crops? and b) how does the sensitivity of crop cover to climate variability vary in different agro-ecological regions with diverse socio-economic factors? We use remote sensing data (2000-01 - 2012-13) for cropping patterns (developed using MODIS satellite data), climate parameters (derived from MODIS and TRMM satellite data) and agricultural census data. We initially assessed the importance of these climate variables in two agro-ecoregions: a predominantly groundwater irrigated, cash crop region in western India, and a region in central India primarily comprised of rain-fed or surface water irrigated subsistence crops. Seasonal crop cover anomaly varied between -25% and 25% of the 13-year mean in these two regions. Predominantly climate-dependent region in central India showed high anomalies up to 200% of the 13-year crop cover mean, especially during winter season. Winter daytime mean temperature is overwhelmingly the most important climate variable for winter crops irrespective of the varied biophysical and socio-economic conditions across the study regions. Despite access to groundwater irrigation, crop cover in the western Indian study region showed substantial fluctuations during monsoon, probably due to changing planting strategies. This region is less sensitive to precipitation compared to the central Indian study region with predominantly climate-dependent irrigation from surface water. In western Indian study region a greater number of rainy days, increased intensity of rainfall, and cooler daytime and nighttime temperatures lead to increased crop cover during monsoon season, compared to in the central Indian study region where monsoon timing and amount of total rainfall are the most important factors of crop cover. Our findings indicate that different regions respond differently to climate, since socio-economic factors, such as irrigation access, market influences, demography, and policies play critical role in agricultural production. In the wake of projected precipitation and temperature changes, better access to irrigation and heat-tolerant high-yielding crop varieties will be crucial for future food production.

The growth of the central region by acquisition of counterrotating gas in star-forming galaxies

PubMed Central

Chen, Yan-Mei; Shi, Yong; Tremonti, Christy A.; Bershady, Matt; Merrifield, Michael; Emsellem, Eric; Jin, Yi-Fei; Huang, Song; Fu, Hai; Wake, David A.; Bundy, Kevin; Stark, David; Lin, Lihwai; Argudo-Fernandez, Maria; Bergmann, Thaisa Storchi; Bizyaev, Dmitry; Brownstein, Joel; Bureau, Martin; Chisholm, John; Drory, Niv; Guo, Qi; Hao, Lei; Hu, Jian; Li, Cheng; Li, Ran; Lopes, Alexandre Roman; Pan, Kai-Ke; Riffel, Rogemar A.; Thomas, Daniel; Wang, Lan; Westfall, Kyle; Yan, Ren-Bin

2016-01-01

Galaxies grow through both internal and external processes. In about 10% of nearby red galaxies with little star formation, gas and stars are counter-rotating, demonstrating the importance of external gas acquisition in these galaxies. However, systematic studies of such phenomena in blue, star-forming galaxies are rare, leaving uncertain the role of external gas acquisition in driving evolution of blue galaxies. Here, based on new measurements with integral field spectroscopy of a large representative galaxy sample, we find an appreciable fraction of counter-rotators among blue galaxies (9 out of 489 galaxies). The central regions of blue counter-rotators show younger stellar populations and more intense, ongoing star formation than their outer parts, indicating ongoing growth of the central regions. The result offers observational evidence that the acquisition of external gas in blue galaxies is possible; the interaction with pre-existing gas funnels the gas into nuclear regions (<1 kpc) to form new stars. PMID:27759033

The growth of the central region by acquisition of counterrotating gas in star-forming galaxies.

PubMed

Chen, Yan-Mei; Shi, Yong; Tremonti, Christy A; Bershady, Matt; Merrifield, Michael; Emsellem, Eric; Jin, Yi-Fei; Huang, Song; Fu, Hai; Wake, David A; Bundy, Kevin; Stark, David; Lin, Lihwai; Argudo-Fernandez, Maria; Bergmann, Thaisa Storchi; Bizyaev, Dmitry; Brownstein, Joel; Bureau, Martin; Chisholm, John; Drory, Niv; Guo, Qi; Hao, Lei; Hu, Jian; Li, Cheng; Li, Ran; Lopes, Alexandre Roman; Pan, Kai-Ke; Riffel, Rogemar A; Thomas, Daniel; Wang, Lan; Westfall, Kyle; Yan, Ren-Bin

2016-10-19

Galaxies grow through both internal and external processes. In about 10% of nearby red galaxies with little star formation, gas and stars are counter-rotating, demonstrating the importance of external gas acquisition in these galaxies. However, systematic studies of such phenomena in blue, star-forming galaxies are rare, leaving uncertain the role of external gas acquisition in driving evolution of blue galaxies. Here, based on new measurements with integral field spectroscopy of a large representative galaxy sample, we find an appreciable fraction of counter-rotators among blue galaxies (9 out of 489 galaxies). The central regions of blue counter-rotators show younger stellar populations and more intense, ongoing star formation than their outer parts, indicating ongoing growth of the central regions. The result offers observational evidence that the acquisition of external gas in blue galaxies is possible; the interaction with pre-existing gas funnels the gas into nuclear regions (<1 kpc) to form new stars.

Earth and water resources and hazards in Central America

USGS Publications Warehouse

Cunningham, Charles G.; Fary, R.W.; Guffanti, Marianne; Laura, Della; Lee, M.P.; Masters, C.D.; Miller, R.L.; Quinones-Marques, Ferdinand; Peebles, R.W.; Reinemund, J.A.; Russ, D.P.

1984-01-01

Long-range economic development in Central America will depend in large part on production of indigenous mineral, energy, and water resources and on mitigation of the disastrous effects of geologic and hydrologic hazards such as landslides, earthquakes, volcanic eruptions, and floods. The region has six world-class metal mines at present as well as additional evidence of widespread mineralization. Systematic investigations using modern mineral exploration techniques should reveal more mineral deposits suitable for development. Widespread evidence of lignite and geothermal resources suggests that intensive studies could identify producible energy sources in most Central American countries. Water supply and water quality vary greatly from country to country. Local problems of ground- and surface-water availability and of contamination create a need for systematic programs to provide better hydrologic data, capital improvements, and management. Disastrous earthquakes have destroyed or severely damaged many cities in Central America. Volcanic eruptions, landslides, mudflows, and floods have devastated most of the Pacific side of Central America at one time or another. A regional approach to earthquake, volcano, and flood-risk analysis and monitoring, using modern technology and concepts, would provide the facilities and means for acquiring knowledge necessary to reduce future losses. All Central American countries need to strengthen institutions and programs dealing with earth and water resources and natural hazards. Some of these needs may be satisfied through existing or pending projects and technical and economic assistance from U.S. or other sources. The need for a comprehensive study of the natural resources of Central America and the requirements for their development is evident. The U.S. Caribbean Basin Initiative offers both an excellent opportunity for a regional approach to these pervasive problems and an opportunity for international cooperation.

SDSS-IV MaNGA: the spatial distribution of star formation and its dependence on mass, structure, and environment

NASA Astrophysics Data System (ADS)

Spindler, Ashley; Wake, David; Belfiore, Francesco; Bershady, Matthew; Bundy, Kevin; Drory, Niv; Masters, Karen; Thomas, Daniel; Westfall, Kyle; Wild, Vivienne

2018-05-01

We study the spatially resolved star formation of 1494 galaxies in the SDSS-IV MaNGA Survey. Star formation rates (SFRs) are calculated using a two-step process, using H α in star-forming regions and Dn4000 in regions identified as active galactic nucleus/low-ionization (nuclear) emission region [AGN/LI(N)ER] or lineless. The roles of secular and environmental quenching processes are investigated by studying the dependence of the radial profiles of specific star formation rate on stellar mass, galaxy structure, and environment. We report on the existence of `centrally suppressed' galaxies, which have suppressed Specific Star Formation Rate (SSFR) in their cores compared to their discs. The profiles of centrally suppressed and unsuppressed galaxies are distributed in a bimodal way. Galaxies with high stellar mass and core velocity dispersion are found to be much more likely to be centrally suppressed than low-mass galaxies, and we show that this is related to morphology and the presence of AGN/LI(N)ER like emission. Centrally suppressed galaxies also display lower star formation at all radii compared to unsuppressed galaxies. The profiles of central and satellite galaxies are also compared, and we find that satellite galaxies experience lower specific star formation rates at all radii than central galaxies. This uniform suppression could be a signal of the stripping of hot halo gas in the process known as strangulation. We find that satellites are not more likely to be suppressed in their cores than centrals, indicating that the core suppression is an entirely internal process. We find no correlation between the local environment density and the profiles of star formation rate surface density.

Food and water security issues in Russia II: Water security in general population of Russian Arctic, Siberia and Far East, 2000–2011

PubMed Central

Dudarev, Alexey A.; Dushkina, Eugenia V.; Sladkova, Yuliya N.; Alloyarov, Pavel R.; Chupakhin, Valery S.; Dorofeyev, Vitaliy M.; Kolesnikova, Tatjana A.; Fridman, Kirill B.; Evengard, Birgitta; Nilsson, Lena M.

2013-01-01

Background Poor state of water supply systems, shortage of water purification facilities and disinfection systems, low quality of drinking water generally in Russia and particularly in the regions of the Russian Arctic, Siberia and Far East have been defined in the literature. However, no standard protocol of water security assessment has been used in the majority of studies. Study design and methods Uniform water security indicators collected from Russian official statistical sources for the period 2000–2011 were used for comparison for 18 selected regions in the Russian Arctic, Siberia and Far East. The following indicators of water security were analyzed: water consumption, chemical and biological contamination of water reservoirs of Categories I and II of water sources (centralized – underground and surface, and non-centralized) and of drinking water. Results Water consumption in selected regions fluctuated from 125 to 340 L/person/day. Centralized water sources (both underground and surface sources) are highly contaminated by chemicals (up to 40–80%) and biological agents (up to 55% in some regions), mainly due to surface water sources. Underground water sources show relatively low levels of biological contamination, while chemical contamination is high due to additional water contamination during water treatment and transportation in pipelines. Non-centralized water sources are highly contaminated (both chemically and biologically) in 32–90% of samples analyzed. Very high levels of chemical contamination of drinking water (up to 51%) were detected in many regions, mainly in the north-western part of the Russian Arctic. Biological contamination of drinking water was generally much lower (2.5–12%) everywhere except Evenki AO (27%), and general and thermotolerant coliform bacteria predominated in drinking water samples from all regions (up to 17.5 and 12.5%, correspondingly). The presence of other agents was much lower: Coliphages – 0.2–2.7%, Clostridia spores, Giardia cysts, pathogenic bacteria, Rotavirus – up to 0.8%. Of a total of 56 chemical pollutants analyzed in water samples from centralized water supply systems, 32 pollutants were found to be in excess of hygienic limits, with the predominant pollutants being Fe (up to 55%), Cl (up to 57%), Al (up to 43%) and Mn (up to 45%). Conclusion In 18 selected regions of the Russian Arctic, Siberia and Far East Category I and II water reservoirs, water sources (centralized – underground, surface; non-centralized) and drinking water are highly contaminated by chemical and biological agents. Full-scale reform of the Russian water industry and water security system is urgently needed, especially in selected regions. PMID:24350065

Global brain connectivity alterations in patients with schizophrenia and bipolar spectrum disorders.

PubMed

Skåtun, Kristina C; Kaufmann, Tobias; Tønnesen, Siren; Biele, Guido; Melle, Ingrid; Agartz, Ingrid; Alnæs, Dag; Andreassen, Ole A; Westlye, Lars T

2016-08-01

The human brain is organized into functionally distinct modules of which interactions constitute the human functional connectome. Accumulating evidence has implicated perturbations in the patterns of brain connectivity across a range of neurologic and neuropsychiatric disorders, but little is known about diagnostic specificity. Schizophrenia and bipolar disorders are severe mental disorders with partly overlapping symptomatology. Neuroimaging has demonstrated brain network disintegration in the pathophysiologies; however, to which degree the 2 diagnoses present with overlapping abnormalities remains unclear. We collected resting-state fMRI data from patients with schizophrenia or bipolar disorder and from healthy controls. Aiming to characterize connectivity differences across 2 severe mental disorders, we derived global functional connectivity using eigenvector centrality mapping, which allows for regional inference of centrality or importance in the brain network. Seventy-one patients with schizophrenia, 43 with bipolar disorder and 196 healthy controls participated in our study. We found significant effects of diagnosis in 12 clusters, where pairwise comparisons showed decreased global connectivity in high-centrality clusters: sensory regions in patients with schizophrenia and subcortical regions in both patient groups. Increased connectivity occurred in frontal and parietal clusters in patients with schizophrenia, with intermediate effects in those with bipolar disorder. Patient groups differed in most cortical clusters, with the strongest effects in sensory regions. Methodological concerns of in-scanner motion and the use of full correlation measures may make analyses more vulnerable to noise. Our results show decreased eigenvector centrality of limbic structures in both patient groups and in sensory regions in patients with schizophrenia as well as increased centrality in frontal and parietal regions in both groups, with stronger effects in patients with schizophrenia.

Effects of irrigation on sorghum forage yield and quality in the central sands region of Wisconsin

USDA-ARS?s Scientific Manuscript database

A study was conducted to assess effects of irrigation on yield and quality of photoperiod sensitive (PS) and non-PS forage sorghum, sorghum-sudangrass, and sudangrass in comparison to corn in central Wisconsin. The study was a strip-plot design with a 5 x 8 factorial arrangement of treatments. Five ...

TORCAPP: time-dependent cyclotron orbit calculation and plotting package

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malarkey, C.H.; McNeilly, G.S.; Merriman, L.D.

1982-11-01

This addendum describes the modifications and additions to TORCAPP which have been implemented since the original report was issued in November 1979 by L.B. Maddox and G.S. McNeilly. Major changes include input of electric field data for central region studies, provision for extractor elements to allow extraction studies, and three-dimensional tracking of central rays.

RELATIONSHIPS BETWEEN ENVIRONMENTAL VARIABLES AND BENTHIC DIATOM ASSEMBLAGES IN CALIFORNIA CENTRAL VALLEY STREAMS (USA)

EPA Science Inventory

Streams and rivers in the California Central Valley Ecoregion have been substantially modified by human activities. This study examines distributional patterns of benthic diatom assemblages in relation to environmental characteristics in streams and rivers of this region. Benthic...

Chemical mixing model studies of lunar orbital geochemical data - Apollo 16 and 17 highlands compositions

NASA Technical Reports Server (NTRS)

Spudis, P. D.; Hawke, B. R.

1982-01-01

Chemical mixing model studies of lunar geochemical data for the central and Taurus-Littrow lunar highlands were performed utilizing pristine highland rock types as end member compositions. The central highlands show considerable diversity in composition; anorthosite is the principal rock type in the Apollo 16/Descartes region, while norite predominates in the highlands west of the landing site. This change in crustal composition is coincident with a major color boundary seen in earth-based multispectral data and probably represents the presence of distinct geochemical provinces within the central highlands. The Taurus-Littrow highlands are dominated by norite; anorthosite is far less abundant than in the central highlands. This suggests that the impact target for the Serenitatis basin was different than that of the Nectaris basin and further strengthens the hypothesis that the lunar highlands are petrologically heterogeneous on a regional basis. It is suggested that the lunar highlands should be viewed in terms of geochemical provinces that have undergone distinct and complex igneous and impact histories.

Comprehending expository texts: the dynamic neurobiological correlates of building a coherent text representation

PubMed Central

Swett, Katherine; Miller, Amanda C.; Burns, Scott; Hoeft, Fumiko; Davis, Nicole; Petrill, Stephen A.; Cutting, Laurie E.

2013-01-01

Little is known about the neural correlates of expository text comprehension. In this study, we sought to identify neural networks underlying expository text comprehension, how those networks change over the course of comprehension, and whether information central to the overall meaning of the text is functionally distinct from peripheral information. Seventeen adult subjects read expository passages while being scanned using functional magnetic resonance imaging (fMRI). By convolving phrase onsets with the hemodynamic response function (HRF), we were able to identify regions that increase and decrease in activation over the course of passage comprehension. We found that expository text comprehension relies on the co-activation of the semantic control network and regions in the posterior midline previously associated with mental model updating and integration [posterior cingulate cortex (PCC) and precuneus (PCU)]. When compared to single word comprehension, left PCC and left Angular Gyrus (AG) were activated only for discourse-level comprehension. Over the course of comprehension, reliance on the same regions in the semantic control network increased, while a parietal region associated with attention [intraparietal sulcus (IPS)] decreased. These results parallel previous findings in narrative comprehension that the initial stages of mental model building require greater visuospatial attention processes, while maintenance of the model increasingly relies on semantic integration regions. Additionally, we used an event-related analysis to examine phrases central to the text's overall meaning vs. peripheral phrases. It was found that central ideas are functionally distinct from peripheral ideas, showing greater activation in the PCC and PCU, while over the course of passage comprehension, central and peripheral ideas increasingly recruit different parts of the semantic control network. The finding that central information elicits greater response in mental model updating regions than peripheral ideas supports previous behavioral models on the cognitive importance of distinguishing textual centrality. PMID:24376411

Temporal patterns of woody species diversity in a central Appalachian forest from 1856 to 1997

Treesearch

Thomas M. Schuler; Andrew R. Gillespie

2000-01-01

This study examined the composition of woody species in a mixed mesophytic forest in the central Appalachian region with respect to both time and different disturbance regimes. Species composition and diversity were assessed from 1856 to 1997 on a tract of land that currently is part of the Fernow Experimental Forest in north-central West Virginia. Additionally, the...

Importance of U.S. 395 Corridor For Local and Regional Commerce in South Central Washington

DOT National Transportation Integrated Search

1995-04-01

This study examined the importance of the U.S. 395 corridor area for local and regional commerce. The analysis focuses on the use and importance of the highway system for local and regional commerce. However, it is recognized that the highway system ...

EPA's Role with the Regional Environmental Center (REC) for Central and Eastern Europe

EPA Pesticide Factsheets

The Regional Environmental Center (REC) for Central and Eastern Europe provides assistance in solving environmental problems in Central and Eastern Europe by promoting cooperation among governments, non-governmental organizations, businesses and others.

Determining the best forecasting method to estimate unitary charges price indexes of PFI data in central region Peninsular Malaysia

NASA Astrophysics Data System (ADS)

Ahmad Kamaruddin, Saadi Bin; Md Ghani, Nor Azura; Mohamed Ramli, Norazan

2013-04-01

The concept of Private Financial Initiative (PFI) has been implemented by many developed countries as an innovative way for the governments to improve future public service delivery and infrastructure procurement. However, the idea is just about to germinate in Malaysia and its success is still vague. The major phase that needs to be given main attention in this agenda is value for money whereby optimum efficiency and effectiveness of each expense is attained. Therefore, at the early stage of this study, estimating unitary charges or materials price indexes in each region in Malaysia was the key objective. This particular study aims to discover the best forecasting method to estimate unitary charges price indexes in construction industry by different regions in the central region of Peninsular Malaysia (Selangor, Federal Territory of Kuala Lumpur, Negeri Sembilan, and Melaka). The unitary charges indexes data used were from year 2002 to 2011 monthly data of different states in the central region Peninsular Malaysia, comprising price indexes of aggregate, sand, steel reinforcement, ready mix concrete, bricks and partition, roof material, floor and wall finishes, ceiling, plumbing materials, sanitary fittings, paint, glass, steel and metal sections, timber and plywood. At the end of the study, it was found that Backpropagation Neural Network with linear transfer function produced the most accurate and reliable results for estimating unitary charges price indexes in every states in central region Peninsular Malaysia based on the Root Mean Squared Errors, where the values for both estimation and evaluation sets were approximately zero and highly significant at p < 0.01. Therefore, artificial neural network is sufficient to forecast construction materials price indexes in Malaysia. The estimated price indexes of construction materials will contribute significantly to the value for money of PFI as well as towards Malaysian economical growth.

(Findings of the Costa Rica power sector efficiency study)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waddle, D.B.

To present findings of the Costa Rica Power Sector Efficiency Study to the Instituto Costarricense de Electridad, and to the Ministry of Energy, Natural Resources and Mining. To discuss the progress and plans for the Central American Rural Electrification Project with US Agency for International Development (USAID)/Regional Office Central American Program (ROCAP). I traveled to San Jose, Costa Rica to present the findings of the Costa Rica Power Sector Efficiency Study to our counterparts in the utility and the Ministry of Energy. Discussions were held with line level managers at Instituto Costarricensede Electricidad (ICE) and Ministry of Energy Mines andmore » Natural Resources (MIRENEM), as well as a plan of action set for the final stage of the project. Discussions were held for a one day period with both the bilateral Agency for International Development (AID) and the regional AID mission regarding the need for a similar study in Guatemala and matters directly pertaining to the Central American Rural Electrification Study (CARES) project.« less

Periodontal disease awareness among pregnant women in the central and eastern regions of Saudi Arabia.

PubMed

Asa'ad, Farah A; Rahman, Ghousia; Al Mahmoud, Noura; Al Shamasi, Ebtehaj; Al Khuwaileidi, Abrar

2015-02-01

The purpose of this study was to assess the knowledge and awareness regarding periodontal disease and its effects on pregnancy among pregnant women in the central and eastern regions of Saudi Arabia. In this cross-sectional survey, self-administered, structured questionnaires were distributed to 300 pregnant women who were chosen randomly from attendees of maternity health care centers in the central and eastern regions of Saudi Arabia. The questions were developed from literature reviews of articles. The questionnaire addressed personal and sociodemographic variables, periodontal health awareness, and knowledge of pregnant women. The questionnaire was translated into Arabic and was pretested during the pilot study on a random sample of 50 pregnant women. Data were analyzed by χ(2) -tests, with the level of significance set at P < 0.05. An overall response rate of 81% was obtained. Approximately 53% had a higher level of education, but only 21% knew how to define dental plaque and 30% knew its harmful effects. Almost 73% stated that gum disease could be prevented through toothbrushing and flossing. Approximately 97% of the respondents knew the negative effect of smoking, while only 12% knew there was a possible relationship between periodontal disease and adverse pregnancy outcomes. The results of this cross-sectional study found that there is limited knowledge and awareness about periodontal disease and its possible effects on pregnancy among pregnant women attending maternal health care centers in the central and eastern regions of Saudi Arabia. © 2013 Wiley Publishing Asia Pty Ltd.

Lightning Evolution In Two North Central Florida Summer Multicell Storms and Three Winter/Spring Frontal Storms

NASA Astrophysics Data System (ADS)

Caicedo, J. A.; Uman, M. A.; Pilkey, J. T.

2018-01-01

We present the first lightning evolution studies, via the Lightning Mapping Array (LMA) and radar, performed in North Central Florida. Parts of three winter/spring frontal storms (cold season) and two complete summer (warm season) multicell storms are studied. Storm parameters measured are as follows: total number of flashes, flash-type classification, first flashes, flash initiation altitude, flash initiation power, flash rate (flashes per minute), charge structure, altitude and temperature ranges of the inferred charge regions, atmospheric isotherm altitude, radar base reflectivity (dBZ), and radar echo tops (EET). Several differences were found between summer multicell and winter/spring frontal storms in North Central Florida: (1) in winter/spring storms, the range of altitudes that all charge regions occupy is up to 1 km lower in altitude than in summer storms, as are the 0°C, -10°C, and -20°C isotherms; (2) lightning activity in summer storms is highly correlated with changes in radar signatures, in particular, echo tops; and (3) the LMA average initiation power of all flash types in winter/frontal storms is about an order of magnitude larger than that for summer storms. In relation to storms in other geographical locations, North Central Florida seasonal storms were found to have similarities in most parameters studied with a few differences, examples in Florida being (1) colder initiation altitudes for intracloud flashes, (2) charge regions occupying larger ranges of atmospheric temperatures, and (3) winter/spring frontal storms not having much lightning activity in the stratiform region.

Sonoanatomy relevant for ultrasound-guided central neuraxial blocks via the paramedian approach in the lumbar region

PubMed Central

Karmakar, M K; Li, X; Kwok, W H; Ho, A M-H; Ngan Kee, W D

2012-01-01

Objectives The use of ultrasound to guide peripheral nerve blocks is now a well-established technique in regional anaesthesia. However, despite reports of ultrasound guided epidural access via the paramedian approach, there are limited data on the use of ultrasound for central neuraxial blocks, which may be due to a poor understanding of spinal sonoanatomy. The aim of this study was to define the sonoanatomy of the lumbar spine relevant for central neuraxial blocks via the paramedian approach. Methods The sonoanatomy of the lumbar spine relevant for central neuraxial blocks via the paramedian approach was defined using a “water-based spine phantom”, young volunteers and anatomical slices rendered from the Visible Human Project data set. Results The water-based spine phantom was a simple model to study the sonoanatomy of the osseous elements of the lumbar spine. Each osseous element of the lumbar spine, in the spine phantom, produced a “signature pattern” on the paramedian sagittal scans, which was comparable to its sonographic appearance in vivo. In the volunteers, despite the narrow acoustic window, the ultrasound visibility of the neuraxial structures at the L3/L4 and L4/L5 lumbar intervertebral spaces was good, and we were able to delineate the sonoanatomy relevant for ultrasound-guided central neuraxial blocks via the paramedian approach. Conclusion Using a simple water-based spine phantom, volunteer scans and anatomical slices from the Visible Human Project (cadaver) we have described the sonoanatomy relevant for ultrasound-guided central neuraxial blocks via the paramedian approach in the lumbar region. PMID:22010025

Regional Strategic Appraisal of Central America

DTIC Science & Technology

2003-04-07

effective region, to increase its competitiveness in the face of the challenges from globalization . Therefore, I recommend a deepening of the regional...centroamericanos, 1970 a 1999, Mexico City, Mach 2000. 7 Agosin, Bloom and Gitli, Globalization , Liberalization, and Sustainable Human Development in Central...Bloom, and Eduardo Gitli, “ Globalization , Liberalization, and Sustainable Human Development in Central America,” February, 2000; available from <http

Health disparities among the western, central and eastern rural regions of China after a decade of health promotion and disease prevention programming.

PubMed

Zhang, Xi-Fan; Tian, Xiang-Yang; Cheng, Yu-Lan; Feng, Zhan-Chun; Wang, Liang; Southerland, Jodi

2015-08-01

Health disparities between the western, central and eastern regions of rural China, and the impact of national health improvement policies and programming were assessed. A total of 400 counties were randomly sampled. ANOVA and Logistic regression modeling were employed to estimate differences in health outcomes and determinants. Significant differences were found between the western, central and eastern rural regions in community infrastructure and health outcomes. From 2000 to 2010, health indicators in rural China were improved significantly, and the infant mortality rate (IMR), maternal mortality rate (MMR) and under 5 mortality rate (U5MR) had fallen by 62.79%, 71.74% and 61.92%, respectively. Central rural China had the greatest decrease in IMR (65.05%); whereas, western rural China had the greatest reduction in MMR (72.99%) but smallest reduction in U5MR (57.36%). Despite these improvements, Logistic regression analysis showed regional differences in key health outcome indicators (odds ratios): IMR (central: 2.13; western: 5.31), U5MR (central: 2.25; western: 5.69), MMR (central: 1.94; western: 3.31), and prevalence of infectious diseases (central: 1.62; western: 3.58). The community infrastructure and health outcomes of the western and central rural regions of China have been improved markedly during the first decade of the 21st century. However, health disparities still exist across the three regions. National efforts to increase per capita income, community empowerment and mobilization, community infrastructure, capacity of rural health facilities, and health literacy would be effective policy options to attain health equity.

Health challenges in Kazakhstan and Central Asia.

PubMed

Adambekov, Shalkar; Kaiyrlykyzy, Aiym; Igissinov, Nurbek; Linkov, Faina

2016-01-01

The Central Asian region, which encompasses Kazakhstan, Uzbekistan, Tajikistan, Turkmenistan and Kyrgyzstan, is an interesting geographic region with a rich history dating back to the Silk Road, Mongol conquests and expansion of the Russian Empire. However, from a public health viewpoint, the Central Asian region is under-investigated, and many public health challenges exist, as countries of Central Asia inherited the centralised medical systems practiced in the Soviet Union, and are currently undergoing rapid transitions. A large number of low and middle-income countries around the world, including countries of Central Asia, face a double burden of chronic and infectious disease. This essay focuses on the exploration of the most important public health challenges in the Central Asian region, including limited scientific productivity, the double burden of chronic and infectious disease, the need for healthcare reform and the reduction in care variation. Central Asia has a large number of medical schools, medical centres, and emerging research institutes that can be used to foster a change in medical and public health practice in the region. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

A reconnaissance study of the effect of irrigated agriculture on water quality in the Ogallala Formation, Central High Plains Aquifer

USGS Publications Warehouse

McMahon, Peter B.

2000-01-01

In 1998, the U.S. Geological Survey's National Water-Quality Assessment (NAWQA) Program began a regional study of water quality in the High Plains aquifer. The High Plains aquifer underlies an area of about 174,000 square miles in parts of eight States. Because of its large size, the High Plains aquifer has been divided into three regions: the Southern High Plains, Central High Plains, and Northern High Plains. Although an assessment of water quality in each of the three regions is planned, the initial focus will be the Central High Plains aquifer. Anyone who has flown over the Central High Plains in the summer and has seen the large green circles associated with center pivot sprinklers knows that irrigated agriculture is a widespread land use. Pesticides and fertilizers applied on those irrigated fields will not degrade ground-water quality if they remain in or above the root zone. However, if those chemicals move downward through the unsaturated zone to the water table, they may degrade the quality of the ground water. Water is the principal agent for transporting chemicals from land surface to the water table, and in the semiarid Central High Plains, irrigation often represents the most abundant source of water during the growing season. One objective of NAWQA's High Plains Regional Ground-Water study is to evaluate the effect of irrigated agriculture on the quality of recently recharged water in the Ogallala Formation of the Central High Plains aquifer. The Ogallala Formation is the principal geologic unit in the Central High Plains aquifer, and it consists of poorly sorted clay, silt, sand, and gravel that generally is unconsolidated (Gutentag and others, 1984). Approximately 23 percent of the cropland overlying the Ogallala Formation is irrigated (U.S. Department of Agriculture, 1999). The NAWQA Program generally defines recently recharged ground water to be water recharged in the last 50 years. The water table in the Ogallala Formation is separated from overlying land-use practices by as much as 400 feet of unsaturated sediments. Consequently, one may hypothesize that recently recharged water is not present in the formation. The U.S. Geological Survey conducted a reconnaissance study in 1999 to establish (a) if recently recharged water was present in the Ogallala Formation underlying irrigated cropland and (b) if agricultural land-use practices affect water quality. Results from the reconnaissance study will be used to determine whether a full-scale land-use study is warranted.

Updated azca (Farallon)—South America relative motions during the last 40 My: implications for mountain building in the central Andean region

NASA Astrophysics Data System (ADS)

Somoza, R.

1998-05-01

Recently published seafloor data around the Antarctica plate boundaries, as well as calibration of the Cenozoic Magnetic Polarity Time Scale, allow a reevaluation of the Nazca (Farallon)-South America relative convergence kinematics since late Middle Eocene time. The new reconstruction parameters confirm the basic characteristics determined in previous studies. However, two features are notable in the present data set: a strong increase in convergence rate in Late Oligocene time, and a slowdown during Late Miocene time. The former is coeval with the early development of important tectonic characteristics of the present Central Andes, such as compressional failure in wide areas of the region, and the establishment of Late Cenozoic magmatism. This supports the idea that a relationship exists between strong acceleration of convergence and mountain building in the Central Andean region.

Aerosol optical depth over central north Asia based on MODIS-Aqua data

NASA Astrophysics Data System (ADS)

Avgousta Foutsi, Athina; Korras Carraca, Marios Bruno; Matsoukas, Christos; Biskos, George

2016-04-01

Atmospheric aerosols, both natural and anthropogenic, can affect the regional and global climate through their direct, indirect, and semi-direct effects on the radiative energy budget of the Earth-atmosphere system. To quantify these effects it is important to determine the aerosol load, and an effective way to do that is by measuring the aerosol optical depth (AOD). The central Asia region (mainly the Caspian and Aral sea basins), the arid and semi-arid regions of Western China as well as Siberia are of great interest due to the significant natural sources of mineral aerosols originating from local deserts and biomass burning from wildfires in boreal forests. What is of particular interest in the region is the phenomenal shrinking and desertification of the Aral Sea that drives an intense salt and dust transport from the exposed sea-bed to the surrounding regions with important implications in regional air quality. Anthropogenic particles are also observed due to fossil-fuel combustion occurring mainly at oil refineries in the Caspian Sea basin. Here we investigate the spatial and temporal variability of the AOD at 550 nm over central Asia, Siberia and western China, in the region located between 35° N - 65° N and 45° E - 110° E. For our analysis we use Level-3 daily MODIS - Aqua Dark Target - Deep Blue combined product, from the latest collection (006), available in a 1°×1° resolution (ca. 100 km × 100 km) over the period 2002-2014. Our results indicate a significant spatial variability of the aerosol load over the study region. The highest AODs are observed over the Aral Sea year-round, with extreme values reaching 2.1 during July. In the rest of our study region a clear seasonal cycle with highest AOD values (up to 1.2 over the Taklamakan Desert) during spring and summer is observed. The arid parts of central north Asia are characterized by larger aerosol loads during spring, lower but still high AOD in summer and much lower values in autumn and spring. In the northern and northeastern parts of our study region (Siberia), the relatively high AOD observed during summer (reaching or exceeding 0.5) is most likely associated with biomass burning (wildfires). Most parts of our study region exhibit an overall increasing AOD trend during the study period. The changes are more pronounced over and around the Aral Sea (relative change exceeding 50%), and are stronger during the warm period of the year (April to September). First comparisons with the trends of other possible aerosol sources in the region suggest that the observed overall trend is primarily associated with the increased dust transport from the exposed Aral Sea sea-bed under strong northerly and north-easterly winds.

SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model.

PubMed

Petrov, Anton; Perekhvatova, Natalia; Skulachev, Maxim; Stein, Linda; Ousler, George

2016-01-01

This Phase 2 clinical trial assessed the efficacy and safety of the novel antioxidative, renewable compound SkQ1 for topical treatment of dry eye signs and symptoms. In a single-center, randomized, double-masked, placebo-controlled, 29-day study, 91 subjects with mild to moderate dry eye instilled the study drug twice daily and recorded dry eye symptoms daily. Subjects were randomized 1:1:1 into one of three ophthalmic solution treatment groups: SkQ1 1.55 µg/mL, SkQ1 0.155 µg/mL, or 0.0 µg/mL (placebo). Subjects were exposed to a controlled adverse environment chamber at 3 of the 4 study visits (Day -7, Day 1, and Day 29). Investigator assessments occurred at all study visits. SkQ1 was safe and efficacious in treating dry eye signs and symptoms. Statistically significant improvements with SkQ1 compared to placebo occurred for the dry eye signs of corneal fluorescein staining and lissamine green staining in the central region and lid margin redness, and for the dry eye symptoms of ocular discomfort, dryness, and grittiness. In addition, SkQ1 demonstrated greater efficacy compared to placebo, although the differences were not statistically significant, for corneal fluorescein staining in other regions and/or time points (total staining score, central region, corneal sum score, and temporal region), lissamine green staining for the central and nasal regions, and blink rate scores. This Phase 2 study indicated that SkQ1 is safe and efficacious for the treatment of dry eye signs and symptoms and supported previous study results. Clinicaltrials.gov identifier: NCT02121301. Miotech S.A.

The central element of the synaptonemal complex in mice is organized as a bilayered junction structure.

PubMed

Hernández-Hernández, Abrahan; Masich, Sergej; Fukuda, Tomoyuki; Kouznetsova, Anna; Sandin, Sara; Daneholt, Bertil; Höög, Christer

2016-06-01

The synaptonemal complex transiently stabilizes pairing interactions between homologous chromosomes during meiosis. Assembly of the synaptonemal complex is mediated through integration of opposing transverse filaments into a central element, a process that is poorly understood. We have, here, analyzed the localization of the transverse filament protein SYCP1 and the central element proteins SYCE1, SYCE2 and SYCE3 within the central region of the synaptonemal complex in mouse spermatocytes using immunoelectron microscopy. Distribution of immuno-gold particles in a lateral view of the synaptonemal complex, supported by protein interaction data, suggest that the N-terminal region of SYCP1 and SYCE3 form a joint bilayered central structure, and that SYCE1 and SYCE2 localize in between the two layers. We find that disruption of SYCE2 and TEX12 (a fourth central element protein) localization to the central element abolishes central alignment of the N-terminal region of SYCP1. Thus, our results show that all four central element proteins, in an interdependent manner, contribute to stabilization of opposing N-terminal regions of SYCP1, forming a bilayered transverse-filament-central-element junction structure that promotes synaptonemal complex formation and synapsis. © 2016. Published by The Company of Biologists Ltd.

Experimental Study of Small-Scale Mineral Particles in the Atmosphere of Central Asia

NASA Astrophysics Data System (ADS)

Adushkin, V. V.; Chen, B. B.; Popel, S. I.; Dubinskii, A. Yu.; Weidler, P. G.; Friedrich, F.

2018-03-01

An experimental study of small-scale mineral particles in the atmosphere over Kyrgyzstan is carried out. It is shown that the substance of the studied particles corresponds to quartz-enriched minerals, feldspars, layered silicates, minerals containing lime carbonate, etc. Overall, there is a definite correspondence between the mineral particle compositions in the atmosphere of Kyrgyzstan and in the other regions of Central Asia. The constructed size-distribution functions of the particles agree with the results of studying the dust aerosol properties in the deserts of Central Asia obtained in the southwestern part of Tajikistan in 1989.

Isotopic composition in precipitation and groundwater in the northern mountainous region of the Central Valley of Costa Rica.

PubMed

Sánchez-Murillo, Ricardo; Esquivel-Hernández, Germain; Sáenz-Rosales, Oscar; Piedra-Marín, Gilberto; Fonseca-Sánchez, Alicia; Madrigal-Solís, Helga; Ulloa-Chaverri, Franz; Rojas-Jiménez, Luis D; Vargas-Víquez, José A

2017-03-01

The linkage between precipitation and recharge is still poorly understood in the Central America region. This study focuses on stable isotopic composition in precipitation and groundwater in the northern mountainous region of the Central Valley of Costa Rica. During the dry season, rainfall samples corresponded to enriched events with high deuterium excess. By mid-May, the Intertropical Convergence Zone poses over Costa Rica resulting in a depletion of 18 O/ 16 O and 2 H/H ratios. A parsimonious four-variable regression model (r 2  = 0.52) was able to predict daily δ 18 O in precipitation. Air mass back trajectories indicated a combination of Caribbean Sea and Pacific Ocean sources, which is clearly depicted in groundwater isoscape. Aquifers relying on Pacific-originated recharge exhibited a more depleted pattern, whereas recharge areas relying on Caribbean parental moisture showed an enrichment trend. These results can be used to enhance modelling efforts in Central America where scarcity of long-term data limits water resources management plans.

Regulatory Regionalism and Education: The European Union in Central Asia

ERIC Educational Resources Information Center

Jones, Peter

2010-01-01

This paper investigates the purchase which Jayasuriya's regulatory regionalism approach offers for an analysis of the European Union's engagement in Central Asia. The European Union has a clearly articulated strategy through which to pursue what it sees as its interests in Central Asia and the development of a range of EU-Central Asia education…

Remote sensing-based characterization of rainfall during atmospheric rivers over the central United States

NASA Astrophysics Data System (ADS)

Nayak, Munir A.; Villarini, Gabriele

2018-01-01

Atmospheric rivers (ARs) play a central role in the hydrology and hydroclimatology of the central United States. More than 25% of the annual rainfall is associated with ARs over much of this region, with many large flood events tied to their occurrence. Despite the relevance of these storms for flood hydrology and water budget, the characteristics of rainfall associated with ARs over the central United has not been investigated thus far. This study fills this major scientific gap by describing the rainfall during ARs over the central United States using five remote sensing-based precipitation products over a 12-year study period. The products we consider are: Stage IV, Tropical Rainfall Measuring Mission - Multi-satellite Precipitation Analysis (TMPA, both real-time and research version); Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks (PERSIANN); the CPC MORPHing Technique (CMORPH). As part of the study, we evaluate these products against a rain gauge-based dataset using both graphical- and metrics-based diagnostics. Based on our analyses, Stage IV is found to better reproduce the reference data. Hence, we use it for the characterization of rainfall in ARs. Most of the AR-rainfall is located in a narrow region within ∼150 km on both sides of the AR major axis. In this region, rainfall has a pronounced positive relationship with the magnitude of the water vapor transport. Moreover, we have also identified a consistent increase in rainfall intensity with duration (or persistence) of AR conditions. However, there is not a strong indication of diurnal variability in AR rainfall. These results can be directly used in developing flood protection strategies during ARs. Further, weather prediction agencies can benefit from the results of this study to achieve higher skill of resolving precipitation processes in their models.

Lithospheric Structure of Central Asia

NASA Astrophysics Data System (ADS)

Martin, R. J.; Gulen, L.; Sun, Y.; Toksoz, M. N.

2009-12-01

The active tectonics of Central Asia is the result of ongoing, active continental collision between the Indian and the Eurasian plates. This geologically and tectonically complex area is also one of the most seismically active regions in the world. Previous studies in this region mostly depended on teleseismic data and the local and regional data from the stations located in China. In this study we used the local travel time data from Kazakhstan, Kyrgyzstan, Tajikistan, and Uzbekistan to study the lithospheric structure in this region. We selected the events and stations between 32°N-65°E and 45°N-85°E and focused on the areas of Pamir and Tien Shan. In this data set, there are more than 3000 P and S arrivals received at 68 stations from about 220 events. The double difference tomography is applied to relocate events and to invert for seismic structure simultaneously. Our results provide accurate locations of earthquakes and high resolution lithospheric structure in this region. We use both; the local travel times, and also the regional travel times to invert the 3D lithospheric velocity structure in this region. More than 2200 P wave phase picks were used in the inversion. The average grid spacing is 100km and the inverted grids lay on six layers. Then we use the Double Difference Tomography method developed by Zhang and Thurber (2003, 2006) to invert the 3-D P-wave velocity structure. Our tomographic results show highly heterogeneous crust and upper mantle structure for Central Asia. Some crustal low velocity zones are found beneath Tien Shan, the northern Pamir, and the Tajik depression, while high velocity anomalies are found beneath the Kazakh shield, the southern Pamir, and the Tarim basin.

High level of molecular and phenotypic biodiversity in Jatropha curcas from Central America compared to Africa, Asia and South America

PubMed Central

2014-01-01

Background The main bottleneck to elevate jatropha (Jatropha curcas L.) from a wild species to a profitable biodiesel crop is the low genetic and phenotypic variation found in different regions of the world, hampering efficient plant breeding for productivity traits. In this study, 182 accessions from Asia (91), Africa (35), South America (9) and Central America (47) were evaluated at genetic and phenotypic level to find genetic variation and important traits for oilseed production. Results Genetic variation was assessed with SSR (Simple Sequence Repeat), TRAP (Target Region Amplification Polymorphism) and AFLP (Amplified fragment length polymorphism) techniques. Phenotypic variation included seed morphological characteristics, seed oil content and fatty acid composition and early growth traits. Jaccard’s similarity and cluster analysis by UPGM (Unweighted Paired Group Method) with arithmetic mean and PCA (Principle Component Analysis) indicated higher variability in Central American accessions compared to Asian, African and South American accessions. Polymorphism Information Content (PIC) values ranged from 0 to 0.65. In the set of Central American accessions. PIC values were higher than in other regions. Accessions from the Central American population contain alleles that were not found in the accessions from other populations. Analysis of Molecular Variance (AMOVA; P < 0.0001) indicated high genetic variation within regions (81.7%) and low variation across regions (18.3%). A high level of genetic variation was found on early growth traits and on components of the relative growth rate (specific leaf area, leaf weight, leaf weight ratio and net assimilation rate) as indicated by significant differences between accessions and by the high heritability values (50–88%). The fatty acid composition of jatropha oil significantly differed (P < 0.05) between regions. Conclusions The pool of Central American accessions showed very large genetic variation as assessed by DNA-marker variation compared to accessions from other regions. Central American accessions also showed the highest phenotypic variation and should be considered as the most important source for plant breeding. Some variation in early growth traits was found within a group of accessions from Asia and Africa, while these accessions did not differ in a single DNA-marker, possibly indicating epigenetic variation. PMID:24666927

Regional Centre of Expertise (RCE) Graz-Styria: A Process of Mobilization Facing Regional Challenges

ERIC Educational Resources Information Center

Mader, Clemens; Zimmermann, Friedrich M.; Steiner, Gerald; Risopoulos, Filippina

2008-01-01

Purpose: The purpose of this paper is to present how the Regional Centres of Expertise (RCE) Graz-Styria as well as RCEs as instruments can contribute to regional development. The RCE Graz-Styria is representing a case study of Central European RCEs. Design/methodology/approach: The paper describes the development process of RCE Graz-Styria.…

Weather and climate socio-economic impacts in Central America for the management and protection of world heritage sites and the Diquis Delta culture in Costa Rica (a case study)

NASA Astrophysics Data System (ADS)

Amador, J. A.; Alfaro, E. J.

2014-01-01

The Central America region hosts a valuable amount of World Heritage Sites (WHS), many of them located in areas of floods, landslides, drought, high winds, intense precipitations, and earthquakes. The effective management of WHS requires the understanding of this type of environmental phenomena and their potential impacts on these sites. The objective of this work is twofold. To make an analysis of some of the atmospheric systems (easterly waves, cold fronts and tropical cyclones [TCs]) hitting Central America, to estimate their effects on socio-economic activities and potential impacts on WHS during the period 2002-2012. The second objective is to identify, for a case study, the potential effects of hydro-meteorological events associated with a tropical storm on the Diquis Delta region in southern Costa Rica. This site, an important unique archeological site of stone spheres, has been proposed by this country as a WHS. To achieve both, public data bases like HURDAT (North Atlantic Hurricane Database), and information from regional newspapers and National Emergency Committees, among other sources, were used for the study of socio-economic impacts caused by these natural hazards. To accomplish the latter, course resolution NCEP/NCAR (National Center for Environmental Prediction/National Center for Atmospheric Research) Reanalysis atmospheric data served to initialize version 5 of a numerical atmospheric mesoscale model (MM5). This approach permitted to obtain higher resolution gridded data for a set of atmospheric variables for a case study associated with the formation of tropical storm Alma upon the Pacific basin. The MM5 resulted winds and precipitation, among other variables, were then used to evaluate potential impacts on the WHS region. Among the systems analyzed for Central America, TCs were the ones that most severely impacted regional social life and worsened the already weak regional economies. During the period analyzed, TCs affected regions where WHS are very relevant to cultural life and touristic income. The MM5 derived data shows its potential for providing detailed space-time atmospheric data to help quantify and anticipate impacts for WHS protection and management. The overall results are expected to bring the attention of organizations and governments about the importance of socio-economic and cultural losses associated with the impacts caused by natural hazards near WHS in the region.

Recent trends (2003-2013) of land surface heat fluxes on the southern side of the central Himalayas, Nepal

NASA Astrophysics Data System (ADS)

Amatya, Pukar Man; Ma, Yaoming; Han, Cunbo; Wang, Binbin; Devkota, Lochan Prasad

2015-12-01

Novice efforts have been made in order to study the regional distribution of land surface heat fluxes on the southern side of the central Himalayas utilizing high-resolution remotely sensed products, but these have been on instantaneous scale. In this study the Surface Energy Balance System model is used to obtain annual averaged maps of the land surface heat fluxes for 11 years (2003-2013) and study their annual trends on the central Himalayan region. The maps were derived at 5 km resolution using monthly input products ranging from satellite derived to Global Land Data Assimilation System meteorological data. It was found that the net radiation flux is increasing as a result of decreasing precipitation (drier environment). The sensible heat flux did not change much except for the northwestern High Himalaya and High Mountains. In northwestern High Himalaya sensible heat flux is decreasing because of decrease in wind speed, ground-air temperature difference, and increase in winter precipitation, whereas in High Mountains it is increasing due to increase in ground-air temperature difference and high rate of deforestation. The latent heat flux has an overall increasing trend with increase more pronounced in the lower regions compared to high elevated regions. It has been reported that precipitation is decreasing with altitude in this region. Therefore, the increasing trend in latent heat flux can be attributed to increase in net radiation flux under persistent forest cover and irrigation land used for agriculture.

Central diffractive resonance production at the LHC

NASA Astrophysics Data System (ADS)

Fiore, Roberto; Jenkovszky, Laszlo; Schicker, Rainer

2016-07-01

Central production of resonances resulting from the scattering of Pomerons in the central rapidity region of proton-proton scattering is studied. Estimates for relevant cross sections are presented. L.J. gratefully acknowledges an EMMI visiting Professorship at the University of Heidelberg for completion of this work. He is grateful to the organizers of this meeting for their hospitality and support. His work was supported also by DOMUS, Hungarian Academy of Sciences

Predicting Eight Grade Students' Equation Solving Performances via Concepts of Variable and Equality

ERIC Educational Resources Information Center

Ertekin, Erhan

2017-01-01

This study focused on how two algebraic concepts- equality and variable- predicted 8th grade students' equation solving performance. In this study, predictive design as a correlational research design was used. Randomly selected 407 eight-grade students who were from the central districts of a city in the central region of Turkey participated in…

Is there evidence of mesophication of oak forests in the Missouri Ozarks?

Treesearch

Matthew G. Olson; Aaron P. Stevenson; Benjamin O. Knapp; John M. Kabrick; Randy G. Jensen

2014-01-01

Many studies on oak-dominated forests of the Central Hardwood region (CHR) have reported increasing abundance of fire-sensitive species and poor recruitment of oak (Quercus spp.) in the absence of frequent fire. However, most of these studies were conducted in the eastern and central CHR, and the assumption that similar dynamics occur in the western...

Multi-Wavelength Study of W40 HII Region

NASA Astrophysics Data System (ADS)

Shenoy, Sachindev S.; Shuping, R.; Vacca, W. D.

2013-01-01

W40 is an HII region (Sh2-64) within the Serpens molecular cloud in the Aquila rift region. Recent near infrared spectroscopic observations of the brightest members of the central cluster of W40 reveal that the region is powered by at least three early B-type stars and one late O-type star. Near and mid-infrared spectroscopy and photometry, combined with SED modeling of these sources, suggest that the distance to the cluster is between 455 and 535 pc, with about 10 mag of visual extinction. Velocity and extinction measurement of all the nearby regions i.e. Serpens main, Aquila rift, and MWC297 suggest that the entire system (including the W40 extended emission) is associated with the extinction wall at 260 pc. Here we present some preliminary results of a multi-wavelength study of the central cluster and the extended emission of W40. We used Spitzer IRAC data to measure accurate photometry of all the point sources within 4.32 pc of W40 via PRF fitting. This will provide us with a complete census of YSOs in the W40 region. The Spitzer data are combined with publicly available data in 2MASS, WISE and Hershel archives and used to model YSOs in the region. The SEDs and near-IR colors of all the point sources should allow us to determine the age of the central cluster of W40. The results from this work will put W40 in a proper stellar evolutionary context. After subtracting the point sources from the IRAC images, we are able to study the extended emission free from point source contamination. We choose a few morphologically interesting regions in W40 and use the data to model the dust emission. The results from this effort will allow us to study the correlation between dust properties and the large scale physical properties of W40.

Tree Rings as Chroniclers of Mercury Exposure in Shenandoah National Park, Virginia

NASA Astrophysics Data System (ADS)

Riscassi, A. L.; Camper, T.; Lee, T. R.; Druckenbrod, D.; Scanlon, T. M.

2016-12-01

Although historical Hg emissions and subsequent deposition play a dominant role in shaping present and future Hg cycling, our knowledge of this is limited in both space and time. Recent studies have shown Hg concentrations in tree rings have the potential to archive historical Hg exposure from local, regional, and global sources, however, no studies have evaluated tree rings in the eastern U.S., a region of elevated Hg deposition from upwind power plants. In order to chronicle the historical Hg exposure of the central Appalachian region through dendrochemical analysis, tree rings were cored along a latitudinal gradient in Shenandoah National Park with sites clustered in North, Central and Southern regions. Long-lived tree species with low radial permeability, chosen to avoid the potential for chemical translocation, included white oak (Quercus Alba), northern red oak (Quercus rubra), and pitch pine (Pinus rigida). In each of the three regions, we collected a core from three individuals of each tree species (27 total cores) and analyzed each for Hg content in 10-yr increments. Overall, tree ring Hg concentrations (average 0.88 ng Hg g-1) were similar to other studies and varied between species. Temporal tree-core Hg trends did not relate to trends in modeled global atmospheric Hg concentrations or regional sources (e.g., fire, coal production), but rather tracked the use of Hg from a local industrial point source. Contemporary wind data originating from the location of the local Hg source in conjunction with an atmospheric model indicate emissions from the plant likely impact the southern region of the park, with a lesser influence in the central and north regions, matching the longitudinal gradient observed in tree rings. This study raises questions about the extent of historical contamination from the industrial site and demonstrates the potential usefulness of tree ring dendrochemistry for identifying historical sources of atmospheric Hg exposure.

Improved Phase Characterization of Far-Regional Body Wave Arrivals in Central Asia

DTIC Science & Technology

2008-09-30

developing array -based methods that can more accurately characterize far-regional (14*-29*) seismic wavefield structure. Far- regional (14*-29*) seismograms...arrivals with the primary arrivals. These complexities can be region and earthquake specific. The regional seismic arrays that have been built in the last...fifteen years should be a rich data source for the study of far-regional phase behavior. The arrays are composed of high-quality borehole seismometers

Central and eastern Anatolian crustal deformation rate and velocity fields derived from GPS and earthquake data

NASA Astrophysics Data System (ADS)

Simão, N. M.; Nalbant, S. S.; Sunbul, F.; Komec Mutlu, A.

2016-01-01

We present a new strain-rate and associated kinematic model for the eastern and central parts of Turkey. In the east, a quasi N-S compressional tectonic regime dominates the deformation field and is partitioned through the two major structural elements of the region, which are the conjugate dextral strike-slip North Anatolian Fault Zone (NAFZ) and the sinistral strike slip East Anatolian Fault Zone (EAFZ). The observed surface deformation is similar to that inferred by anisotropy studies which sampled the region of the mantle closer to the crust (i.e. the lithospheric mantle and the Moho), and is dependent on the presence or absence of a lithospheric mantle, and of the level of coupling between it and the overlaying crust. The areas of the central and eastern parts of Turkey which are deforming at elevated rates are situated above areas with strong gradients in crustal thickness. This seems to indicate that these transition zones, situated between thinner and thicker crusts, promote more deformation at the surface. The regions that reveal elevated strain-rate values are 1) the Elaziğ-Bingol segment of the EAFZ, 2) the region around the Karlıova triple-junction including the Yedisu segment and the Varto fault, 3) the section of the NAFZ that extends from the Erzincan province up to the NAFZ-Ezinepazarı fault junction, and 4) sections of the Tuz Gölü Fault Zone. Other regions like the Adana basin, a significant part of the Central Anatolian Fault Zone (CAFZ), the Aksaray and the Ankara provinces, are deforming at smaller but still considerable rates and therefore should be considered as areas well capable of producing damaging earthquakes (between M6 and 7). This study also reveals that the central part of Turkey is moving at a faster rate towards the west than the eastern part Turkey, and that the wedge region between the NAFZ and the EAFZ accounts for the majority of the counter clockwise rotation between the eastern and the central parts of Turkey. This change in movement rate and direction could be the cause of the extensional deformation and respective crustal thinning, with the resulting upwelling of warmer upper mantle observed in tomographic studies for the region between the Iskenderun bay and the CAFZ. The partitioning of deformation into an extensional regime could be the cause of the relatively low levels of strain-rate in the south-west part of the EAFZ and the northern part of the Dead Sea Fault Zone. Finally, using this new compilation of GPS data for the central-eastern part of Turkey, we obtained a new Anatolia-Eurasia rotation pole situated at 2.01°W and 31.94°N with a rotation rate of 1.053 ± 0.015° /Ma.

The infield varietu of available forms in the forest-steppe of western part Central Chernozemic region

NASA Astrophysics Data System (ADS)

Belik, Anton; Devyatova, Tatiana; Bozhko, Svetlana; Gorbunova, Yulia

2016-04-01

The infield varietu of available forms in the forest-steppe of western part Central Chernozemic region The Central Chernozemic region of Russia has been a region with a strong agricultural industry and determines the food security of the state by most part. The soil cover of the region is represented mainly by chernozems and is favorable for the cultivation of major crops and produce high crop yields. However, the high development of agriculture in the territory of Central Chernozemic region are led to the development of agrogenic degradation processes which impacts on the growth of the soil cover complexity and contrast, and as a consequence a significant infield variety of soil fertility and yields of major crops. In this regard, very promising direction in CChR is the development and practical application technologies of precision agriculture, which implies the spatial variety of soil fertility analysis within specific fields and work areas, especially the content of available forms of nutrients. The aim of our research was a study of the agro-ecological characteristics of the spatial variety of the content by available forms to plants of major nutrients in representative areas of sloping agricultural landscapes with forest-steppe chernozems in the western part of Central Chernozemic region of Russia. The research of infield variety by content of available forms of major nutrients are carried in the fields of Russian Research Institute of Agriculture and Protect the Soil from Erosion experimental and industrial farm in Medvensky district of Kursk region. The area characterized by a complex organization of relief. The soil cover is represented by full-profile typical (conventional and carbonate), leached chernozems. The growth of contrast of the soil cover are largely determined by the appearance of eroded soils of these analogues, as well as zoogenic dug and accumulative soils All of the studied areas with the forest-steppe chernozems were characterized by pronounced variation in the content of available forms of nitrogen, phosphorus and potassium. In the most varied contents of available phosphorus and potassium (coefficients of variation increase by 1.2 - 1.3 times as the complexity of the soil cover and reduced 1.3 - 1.6 times as reducing the area of the site and the growth detailed studies). The least within the fields of content of nitrogen are varied at its most high average grade. As the most important factors determining the spatial variety of the batteries for the phosphorus and potassium should be made kind of soil, the degree of erosion, the depth of the carbonates. The above factors the humus content is added the level of applied agricultural technologies and the history of land use within the studied areas for the nitrogen. Thus, the identification of significant infield variety in the content of available forms of nutrients in the forest-steppe chernozems is the result of processes of water erosion. In terms of slope forest-steppe agricultural landscapes of Central Chernozemic region of spatial variability of available forms of nitrogen, phosphorus and potassium is an important factor, which is limited the yields and causes the most promising application the technologies of precision agriculture.

Central America: A Regional Study.

ERIC Educational Resources Information Center

Mowry, George; Lacy, Ann

This lesson is a series of activities and multi-media presentations designed to enable students to understand the historic and geographic roots of some of the problems that Central American nations have faced. Geography, history, writing, and storytelling are used as ways of understanding a multicultural world. Creative thinking and participation…

Pilot Study for an Assessment of Vegetation Structure for Steppe Rangelands of Central Anatolia

USDA-ARS?s Scientific Manuscript database

In the last fifty years, rangelands in the Central Anatolian Region of Turkey have been converted to cropping lands, which has negatively accelerated vegetation change, resulting in overgrazing, poor condition and productivity. In these steppe rangelands, to develop a rational basis for making resto...

Planning for Change in Higher Education.

ERIC Educational Resources Information Center

Ostergren, Bertil

This document, adapted to readers who are not familiar with institutional details in Swedish higher education, outlines planning and management at regional and central levels. Emphasis is placed on qualitative aspects of planning and on identification of obstacles and possibilities of change and innovation. A central problem for the study is to…

The implications of trade liberalization for diet and health: a case study from Central America

PubMed Central

Thow, Anne Marie; Hawkes, Corinna

2009-01-01

Background Central America has undergone extensive trade liberalization over the past two decades, and has recently signed a Free Trade Agreement with the United States. The region is also experiencing a dual burden of malnutrition with the growth of dietary patterns associated with the global 'nutrition transition'. This study describes the relationship between trade liberalization policies and food imports and availability, and draws implications for diet and health, using Central America as a case study region. Methods Changes in tariff and non-tariff barriers for each country were documented, and compared with time-series graphs of import, production and availability data to show the outcome of changes in trade policy in relation to food imports and food availability. Results Changes in trade policy in Central America have directly affected food imports and availability via three avenues. First, the lowering of trade barriers has promoted availability by facilitating higher imports of a wide range of foods. Second, trade liberalization has affected food availability through promoting domestic meat production. Third, reductions in barriers to investment appear to be critical in expansion of processed food markets. This suggests that changes in trade policies have facilitated rising availability and consumption of meat, dairy products, processed foods and temperate (imported fruits) in Central America. Conclusion This study indicates that the policies of trade liberalization in Central American countries over the past two decades, particularly in relation to the United States, have implications for health in the region. Specifically, they have been a factor in facilitating the "nutrition transition", which is associated with rising rates of obesity and chronic diseases such as cardiovascular disease and cancer. Given the significant cost of chronic disease for the health care system, individuals and the wider community, it is critical that preventive health measures address such upstream determinants of poor nutrition. PMID:19638196

The implications of trade liberalization for diet and health: a case study from Central America.

PubMed

Thow, Anne Marie; Hawkes, Corinna

2009-07-28

Central America has undergone extensive trade liberalization over the past two decades, and has recently signed a Free Trade Agreement with the United States. The region is also experiencing a dual burden of malnutrition with the growth of dietary patterns associated with the global 'nutrition transition'. This study describes the relationship between trade liberalization policies and food imports and availability, and draws implications for diet and health, using Central America as a case study region. Changes in tariff and non-tariff barriers for each country were documented, and compared with time-series graphs of import, production and availability data to show the outcome of changes in trade policy in relation to food imports and food availability. Changes in trade policy in Central America have directly affected food imports and availability via three avenues. First, the lowering of trade barriers has promoted availability by facilitating higher imports of a wide range of foods. Second, trade liberalization has affected food availability through promoting domestic meat production. Third, reductions in barriers to investment appear to be critical in expansion of processed food markets. This suggests that changes in trade policies have facilitated rising availability and consumption of meat, dairy products, processed foods and temperate (imported fruits) in Central America. This study indicates that the policies of trade liberalization in Central American countries over the past two decades, particularly in relation to the United States, have implications for health in the region. Specifically, they have been a factor in facilitating the "nutrition transition", which is associated with rising rates of obesity and chronic diseases such as cardiovascular disease and cancer. Given the significant cost of chronic disease for the health care system, individuals and the wider community, it is critical that preventive health measures address such upstream determinants of poor nutrition.

Rhipicephalus (Boophilus) microplus in the western-central region of Rio Grande do Sul, Brazil: multiresistant tick.

PubMed

Machado, Fabrício Amadori; Pivoto, Felipe Lamberti; Ferreira, Maiara Sanitá Tafner; Gregorio, Fabiano de Vargas; Vogel, Fernanda Silveira Flores; Sangioni, Luís Antônio

2014-01-01

The aim of the present study was to assess the acaricide resistance of tick populations in the western-central region of Rio Grande do Sul (Brazil), which has not previously been reported. Fifty-four cattle farms were visited and specimens of Rhipicephalus (Boophilus) microplus were collected and subjected to the adult immersion test, using nine commercial acaricides in the amidine, pyrethroid and organophosphate groups. Climatic data, including monthly precipitation, were recorded. The results from the present study demonstrated that seven of the acaricides analyzed presented mean efficacy values of less than 95%, with large differences among the products tested. Nine of them exhibited satisfactory and unsatisfactory acaricide results on at least one farm. In conclusion, the farms located in the western-central region of Rio Grande do Sul, Brazil, exhibited populations of R. (Boophilus) microplus with variable degrees of susceptibility to different acaricides, thus suggesting that resistance to the active compounds exists. It is suggested that treatment protocols should be implemented at the beginning of winter and summer, using the acaricides that showed efficacy in the adult immersion test.

Melioidosis in Mexico, Central America, and the Caribbean

PubMed Central

Sanchez-Villamil, Javier I.; Torres, Alfredo G.

2018-01-01

Burkholderia pseudomallei is the causative agent of melioidosis, an endemic disease in tropical areas around the world. Cumulative human cases have demonstrated that melioidosis is prevalent and increasingly recognized in the American continent. Even though the first reports of melioidosis in Mexico, Central America, and the Caribbean Islands date back to the late 1940s, the potential of the disease as a public health concern in the region has not been fully appreciated. Unfortunately, recent studies predicting the global distribution of the disease and the demonstration of melioidosis endemicity in Puerto Rico have not increased recognition of the disease by health professionals in this region. Furthermore, a lack of both diagnostic capacity and awareness of the disease has resulted in a limited number of studies that have attempted to accurately determine its prevalence and geographical distribution. In this review, a summary of reported cases in the countries of this region are presented, as well as recommendations to increase the diagnosis and awareness of the disease as an important public health problem in Mexico, Central America, and the Caribbean islands. PMID:29780897

Photon-assisted tunneling in an asymmetrically coupled triple quantum dot

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Bao-Chuan; Cao, Gang, E-mail: gcao@ustc.edu.cn; Chen, Bao-Bao

The gate-defined quantum dot is regarded as one of the basic structures required for scalable semiconductor quantum processors. Here, we demonstrate a structure that contains three quantum dots scaled in series. The electron number of each dot and the tunnel coupling between them can be tuned conveniently using splitting gates. We tune the quantum dot array asymmetrically such that the tunnel coupling between the right dot and the central dot is much larger than that between the left dot and the central dot. When driven by microwaves, the sidebands of the photon-assisted tunneling process appear not only in the left-to-centralmore » dot transition region but also in the left-to-right dot transition region. These sidebands are both attributed to the left-to-central transition for asymmetric coupling. Our result shows that there is a region of a triple quantum dot structure that remains indistinct when studied with a normal two-dimensional charge stability diagram; this will be helpful in future studies of the scalability of quantum dot systems.« less

Factors Affecting Regional Per-Capita Carbon Emissions in China Based on an LMDI Factor Decomposition Model

PubMed Central

Dong, Feng; Long, Ruyin; Chen, Hong; Li, Xiaohui; Yang, Qingliang

2013-01-01

China is considered to be the main carbon producer in the world. The per-capita carbon emissions indicator is an important measure of the regional carbon emissions situation. This study used the LMDI factor decomposition model–panel co-integration test two-step method to analyze the factors that affect per-capita carbon emissions. The main results are as follows. (1) During 1997, Eastern China, Central China, and Western China ranked first, second, and third in the per-capita carbon emissions, while in 2009 the pecking order changed to Eastern China, Western China, and Central China. (2) According to the LMDI decomposition results, the key driver boosting the per-capita carbon emissions in the three economic regions of China between 1997 and 2009 was economic development, and the energy efficiency was much greater than the energy structure after considering their effect on restraining increased per-capita carbon emissions. (3) Based on the decomposition, the factors that affected per-capita carbon emissions in the panel co-integration test showed that Central China had the best energy structure elasticity in its regional per-capita carbon emissions. Thus, Central China was ranked first for energy efficiency elasticity, while Western China was ranked first for economic development elasticity. PMID:24353753

Factors affecting regional per-capita carbon emissions in China based on an LMDI factor decomposition model.

PubMed

Dong, Feng; Long, Ruyin; Chen, Hong; Li, Xiaohui; Yang, Qingliang

2013-01-01

China is considered to be the main carbon producer in the world. The per-capita carbon emissions indicator is an important measure of the regional carbon emissions situation. This study used the LMDI factor decomposition model-panel co-integration test two-step method to analyze the factors that affect per-capita carbon emissions. The main results are as follows. (1) During 1997, Eastern China, Central China, and Western China ranked first, second, and third in the per-capita carbon emissions, while in 2009 the pecking order changed to Eastern China, Western China, and Central China. (2) According to the LMDI decomposition results, the key driver boosting the per-capita carbon emissions in the three economic regions of China between 1997 and 2009 was economic development, and the energy efficiency was much greater than the energy structure after considering their effect on restraining increased per-capita carbon emissions. (3) Based on the decomposition, the factors that affected per-capita carbon emissions in the panel co-integration test showed that Central China had the best energy structure elasticity in its regional per-capita carbon emissions. Thus, Central China was ranked first for energy efficiency elasticity, while Western China was ranked first for economic development elasticity.

Residues of legacy organochlorine contaminants in the milk of Alpine and Saanen goats from the central region of Mexico.

PubMed

Schettino, Beatriz; Gutiérrez, Rey; Ortiz, Rutilio; Vega, Salvador; Urban, Georgina; Ramírez, Acacia

2013-08-01

This study investigated a suite of legacy organochlorine contaminants in the milk of two breeds of goats raised in the central region of Mexico, where this agricultural production is of national (Mexican) economic importance. Forty milk samples from Alpine and Saanen goats were assessed. It was found that the concentrations of the majority of organochlorine pesticides in milk samples were lower than those stipulated in Mexican and international regulation. The values in both breeds of goat exceeded the upper permissible limits of Codex Alimentarius for delta hexachloro cyclohexane (HCH) (17.3 of samples of Saanen) and heptachlor plus heptachlor epoxide (50 % and 13 % of samples). It may be concluded that milk from these goat breeds from central Mexico showed some risks of contamination in certain times of the year (dry season). However, under further assessment and use of pesticides the goat's milk will likely be safe for human consumption and for use in products such as cheeses, regional candies and desserts (cajeta). In recent years, goat milk production has increased in the central regions and it is an economic alternative to milk from livestock. It is necessary to continue the monitoring of goat's milk to assess the presence and control of HCHs through best management practices.

Morphologic and morphometric studies of impact craters in the northern plains of Mars

NASA Technical Reports Server (NTRS)

Barlow, N. G.

1993-01-01

Fresh impact craters in the northern plains of Mars display a variety of morphologic and morphometric properties. Ejecta morphologies range from radial to fluidized, interior features include central peaks and central pits, fluidized morphologies display a range of sinuosities, and depth-diameter ratios are being measured to determine regional variations. Studies of the martian northern plains over the past five years have concentrated in three areas: (1) determining correlations of ejecta morphologies with crater diameter, latitude, and underlying terrain; (2) determining variations in fluidized ejecta blanket sinuosity across the planet; and (3) measurement of depth-diameter ratios and determination of regional variations in this ratio.

[Occupational asthma in the Tunisian central region: etiologies and professional status].

PubMed

Chatti, S; Maoua, M; Rhif, H; Dahmoul, M; Abbassi, A; Mlaouah, A J; Hadj Salah, H; Debbabi, F; Mrizak, N

2011-10-01

To study the etiologies of occupational asthma and determine its impact on the professional status of asthmatic subjects. The authors carried out a descriptive study on all of the cases of asthma recognized as an occupational disease and declared in the private sector over nine years (2000-2008) in the Tunisian central region. Cases (219) of occupational asthma were listed, accounting for 16.8% of all of the occupational diseases recognized during the period studied. Occupational asthma concerned young adults (40±8.2 years), with a predominance of women (67.7%). The textile sector dominated (74.9%). The majority of the employees were exposed to high molecular weight allergens (82.3%) and cotton dust was the principal offending agent (75.3%). Involuntary unemployment was observed in about half of the cases (46.6%) and was associated with an age lower or equal to 35 years (p = 0.01) and under 15 years of professional seniority (p=0.03). Occupational asthma in the Tunisian central region prevails in the textile sector thereby justifying the reinforcement of preventive measures in this branch of industry. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

Study of Star Formation Regions with Molecular Hydrogen Emission Lines

NASA Astrophysics Data System (ADS)

Pak, Soojong

The goal of my dissertation is to understand the large-scale, near-infrared (near-IR) H2 emission from the central kiloparsec (kpc) regions of galaxies, and to study the structure and physics of photon-dominated regions (or photodissociation regions, hereafter PDRs). In order to explore the near-IR H2 lines, our group built the University of Texas near-IR Fabry-Perot Spectrometer optimized for observations of extended, low surface brightness sources. In this instrument project, I designed and built a programmable high voltage DC amplifier for the Fabry-Perot piezoelectric transducers, a temperature-controlled cooling box for the Fabry-Perot etalon, instrument control software, and data reduction software. With this instrument, we observed H2 emission lines in the inner 400 pc of the Galaxy, the central ~1 kpc of NGC 253 and M82, and the star formation regions in the Magellanic Clouds. We also observed the Magellanic Clouds in the CO J=1/to0 line. We found that the H2 emission is very extended in the central kpc of the galaxies and is mostly UV-excited. The ratios of the H2 (1,0) S(1) luminosities to the far-IR continuum luminosities in the central kpc regions do not change from the Galactic center to starburst galaxies and to ultraluminous IR bright galaxies. Using the data from the Magellanic Clouds, we studied the microscopic structure of star forming clouds. We compiled data sets including our H2 (1,0) S(1) and CO J=1/to0 results and published (C scII) and far-IR data from the Magellanic Clouds, and compared these observations with models we made using a PDR code and a radiative transfer code. Assuming the cloud is spherical, we derived the physical sizes of H2, (C scII), and CO emission regions. The average cloud size appears to increase as the metallicity decreases. Our results agree with the theory of photoionization-regulated star formation in which the interplay between the ambipolar diffusion and ionization by far-UV photons determines the size of stable clouds.

Oil and the geopolitics of Central Asia: A "new 'great game'"?

NASA Astrophysics Data System (ADS)

Al-Sati, Saud M.

The nineteenth century rivalry between the Russian Empire and Great Britain over Central Asia, known as the "great game," was triggered by the quest for power and dominance. This study revisits Sir Halford Mackinder's thesis, which viewed the "heartland," consisting of Russia and Central Asia, as being crucial for international politics. It also discusses the influence of Mackinder's ideas on twentieth century geopolitical thinking. The study also examines the common assumption that the new "great game" in Central Asia is evolving around the exploitation of energy resources, and analyzes the consequences of this new factor for the geopolitical significance of the region. The landlocked nature of the Central Asian countries makes it necessary for them to rely on their neighbors for the export of oil and gas to international markets. Thus, the political and economic interests of Russia, Iran, and Turkey motivate them to compete with each other for export routes through their territories. This study also shows that the estimates of Central Asian proven oil reserves are characterized by considerable ambiguity. Estimates vary from seven to twenty-two billion barrels. Despite the fact that these proven oil reserves are limited compared to those of other regions, such as the Middle East, continued exploration is compatible with the Western strategy of energy resource diversification. Another primary aim of American involvement is to prevent the reintegration of Central Asia into the Russian federation and to block Chinese influence in Central Asia. This study reveals that realities in today's Central Asia are different from those of the nineteenth century. Central Asia now consists of independent countries; the competing powers have changed, with the exception of Russia; and oil has emerged as a new factor. However, the perpetual quest for power and dominance that marked the historical "great game" is still at work in the last decade of the twentieth century. Finally, the study shows that the traditional principles of geopolitics are challenged in Central Asia today by cross-border economic and political factors that undermine the importance of territorial control as the key source of power.

Land surface phenological responses to land use and climate variation in a changing Central Asia

NASA Astrophysics Data System (ADS)

Kariyeva, Jahan

During the last few decades Central Asia has experienced widespread changes in land cover and land use following the socio-economic and institutional transformations of the region catalyzed by the USSR collapse in 1991. The decade-long drought events and steadily increasing temperature regimes in the region came on top of these institutional transformations, affecting the long term and landscape scale vegetation responses. This research is based on the need to better understand the potential ecological and policy implications of climate variation and land use practices in the contexts of landscape-scale changes dynamics and variability patterns of land surface phenology responses in Central Asia. The land surface phenology responses -- the spatio-temporal dynamics of terrestrial vegetation derived from the remotely sensed data -- provide measurements linked to the timing of vegetation growth cycles (e.g., start of growing season) and total vegetation productivity over the growing season, which are used as a proxy for the assessment of effects of variations in environmental settings. Local and regional scale assessment of the before and after the USSR collapse vegetation response patterns in the natural and agricultural systems of the Central Asian drylands was conducted to characterize newly emerging links (since 1991) between coupled human and natural systems, e.g., socio-economic and policy drivers of altered land and water use and distribution patterns. Spatio-temporal patterns of bioclimatic responses were examined to determine how phenology is associated with temperature and precipitation in different land use types, including rainfed and irrigated agricultural types. Phenological models were developed to examine relationship between environmental drivers and effect of their altitudinal and latitudinal gradients on the broad-scale vegetation response patterns in non-cropland ecosystems of the desert, steppe, and mountainous regional landscapes of Central Asia. The study results demonstrated that the satellite derived measurements of temporal cycles of vegetation greenness and productivity data was a valuable bioclimatic integrator of climatic and land use variation in Central Asia. The synthesis of broad-scale phenological changes in Central Asia showed that linkages of natural and human systems vary across space and time comprising complex and tightly integrated patterns and processes that are not evident when studied separately.

Coal workers' pneumoconiosis in the United States: regional differences 40 years after implementation of the 1969 Federal Coal Mine Health and Safety Act.

PubMed

Suarthana, Eva; Laney, A Scott; Storey, Eileen; Hale, Janet M; Attfield, Michael D

2011-12-01

To assess whether the recent increases in the prevalence of coal workers' pneumoconiosis (CWP) in the USA reflect increased measured exposures over recent decades, and to identify other potential causative factors. The observed CWP prevalence was calculated for 12,408 underground coal miner participants in the Coal Workers' Health Surveillance Program for the period 2005-2009, stratified by the Mine Safety and Health Administration (MSHA) geographical districts. The predicted prevalence was estimated using a published exposure-response model from a large epidemiological study among U.S. coal miners using dust exposure, tenure, miner's age and coal rank as predictors. χ2 Testing was performed to compare the observed versus predicted CWP prevalence. Observed prevalence was significantly higher than predicted prevalence in MSHA districts 4-7 (central Appalachian region) (10.1% vs. 4.2%; prevalence ratio (PR) 2.4; p<0.001) and significantly lower than predicted in other regions (1.6% vs. 3.6%; PR 0.4; p<0.001). The central Appalachian region had a significantly older workforce with greater mining tenure, a lower proportion of mines with 200 or more employees, and lower seam heights. Significant lower average compliance dust concentrations were reported for this region. The observed CWP prevalence substantially exceeded predicted levels in central Appalachia. However, the increased prevalence was not explained by the measured levels of dust exposures. Likely contributing factors include mine size and low seam mining, which may be associated with higher exposure to silica. Further study is needed to characterise the responsible factors for the elevated CWP rates in central Appalachia.

Seasonal variation and source analysis of persistent organic pollutants in the atmosphere over the western Tibetan Plateau.

PubMed

Zhang, Jingyi; Wang, Xiaoping; Gong, Ping; Wang, Chuanfei; Sun, Dianchao

2018-06-08

Over the past few decades, the Tibetan Plateau (TP) region has become gradually contaminated by persistent organic pollutants (POPs). The picture regarding POPs is clear in the central and southern parts of the TP; however, few observational campaigns have focused on the western TP. To clarify the concentrations, seasonal trends and source regions of POPs in the western TP, a first study of POPs in Muztagh Ata (westerly region) and a long-term (5 years) monitoring program in Ngari (transect region influenced by both the Indian monsoon and westerly climate) were conducted. Except for hexachlorobenzene (HCB) and polychlorinated biphenyls (PCBs), relatively low POP levels were observed in the western TP. In Muztagh Ata, dichlorodiphenyltrichloroethanes (DDTs) showed higher concentrations in winter and lower ones in summer, whereas at Ngari, higher DDTs and hexachlorocyclohexanes (HCHs) concentrations were observed in summer as compared with winter. Source diagnosis indicated that Xinjiang and central Asia were the main source regions for POPs in Muztagh Ata and that westerly winds play a key role in transporting POPs from central Asia. No correlation was found between the height of the atmospheric boundary layer and the concentrations of POPs over the TP.

Spatial genetic structure and regional demography in the southern torrent salamander: Implications for conservation and management

USGS Publications Warehouse

Miller, Mark P.; Haig, Susan M.; Wagner, R.S.

2006-01-01

The Southern torrent salamander (Rhyacotriton variegatus) was recently found not warranted for listing under the US Endangered Species Act due to lack of information regarding population fragmentation and gene flow. Found in small-order streams associated with late-successional coniferous forests of the US Pacific Northwest, threats to their persistence include disturbance related to timber harvest activities. We conducted a study of genetic diversity throughout this species' range to 1) identify major phylogenetic lineages and phylogeographic barriers and 2) elucidate regional patterns of population genetic and spatial phylogeographic structure. Cytochrome b sequence variation was examined for 189 individuals from 72 localities. We identified 3 major lineages corresponding to nonoverlapping geographic regions: a northern California clade, a central Oregon clade, and a northern Oregon clade. The Yaquina River may be a phylogeographic barrier between the northern Oregon and central Oregon clades, whereas the Smith River in northern California appears to correspond to the discontinuity between the central Oregon and northern California clades. Spatial analyses of genetic variation within regions encompassing major clades indicated that the extent of genetic structure is comparable among regions. We discuss our results in the context of conservation efforts for Southern torrent salamanders.

Centrality measures highlight proton traps and access points to proton highways in kinetic Monte Carlo trajectories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krueger, Rachel A.; Haibach, Frederick G.; Fry, Dana L.

2015-04-21

A centrality measure based on the time of first returns rather than the number of steps is developed and applied to finding proton traps and access points to proton highways in the doped perovskite oxides: AZr{sub 0.875}D{sub 0.125}O{sub 3}, where A is Ba or Sr and the dopant D is Y or Al. The high centrality region near the dopant is wider in the SrZrO{sub 3} systems than the BaZrO{sub 3} systems. In the aluminum-doped systems, a region of intermediate centrality (secondary region) is found in a plane away from the dopant. Kinetic Monte Carlo (kMC) trajectories show that thismore » secondary region is an entry to fast conduction planes in the aluminum-doped systems in contrast to the highest centrality area near the dopant trap. The yttrium-doped systems do not show this secondary region because the fast conduction routes are in the same plane as the dopant and hence already in the high centrality trapped area. This centrality measure complements kMC by highlighting key areas in trajectories. The limiting activation barriers found via kMC are in very good agreement with experiments and related to the barriers to escape dopant traps.« less

Food and water security issues in Russia II: water security in general population of Russian Arctic, Siberia and Far East, 2000-2011.

PubMed

Dudarev, Alexey A; Dushkina, Eugenia V; Sladkova, Yuliya N; Alloyarov, Pavel R; Chupakhin, Valery S; Dorofeyev, Vitaliy M; Kolesnikova, Tatjana A; Fridman, Kirill B; Evengard, Birgitta; Nilsson, Lena M

2013-01-01

Poor state of water supply systems, shortage of water purification facilities and disinfection systems, low quality of drinking water generally in Russia and particularly in the regions of the Russian Arctic, Siberia and Far East have been defined in the literature. However, no standard protocol of water security assessment has been used in the majority of studies. Uniform water security indicators collected from Russian official statistical sources for the period 2000-2011 were used for comparison for 18 selected regions in the Russian Arctic, Siberia and Far East. The following indicators of water security were analyzed: water consumption, chemical and biological contamination of water reservoirs of Categories I and II of water sources (centralized--underground and surface, and non-centralized) and of drinking water. Water consumption in selected regions fluctuated from 125 to 340 L/person/day. Centralized water sources (both underground and surface sources) are highly contaminated by chemicals (up to 40-80%) and biological agents (up to 55% in some regions), mainly due to surface water sources. Underground water sources show relatively low levels of biological contamination, while chemical contamination is high due to additional water contamination during water treatment and transportation in pipelines. Non-centralized water sources are highly contaminated (both chemically and biologically) in 32-90% of samples analyzed. Very high levels of chemical contamination of drinking water (up to 51%) were detected in many regions, mainly in the north-western part of the Russian Arctic. Biological contamination of drinking water was generally much lower (2.5-12%) everywhere except Evenki AO (27%), and general and thermotolerant coliform bacteria predominated in drinking water samples from all regions (up to 17.5 and 12.5%, correspondingly). The presence of other agents was much lower: Coliphages--0.2-2.7%, Clostridia spores, Giardia cysts, pathogenic bacteria, Rotavirus--up to 0.8%. Of a total of 56 chemical pollutants analyzed in water samples from centralized water supply systems, 32 pollutants were found to be in excess of hygienic limits, with the predominant pollutants being Fe (up to 55%), Cl (up to 57%), Al (up to 43%) and Mn (up to 45%). In 18 selected regions of the Russian Arctic, Siberia and Far East Category I and II water reservoirs, water sources (centralized--underground, surface; non-centralized) and drinking water are highly contaminated by chemical and biological agents. Full-scale reform of the Russian water industry and water security system is urgently needed, especially in selected regions.

48 CFR 502.101 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Acquisition Service (FAS), a director of a Central Office or Regional office Division responsible for performing contracting or contract administration functions. (b) In FAS Central Office— (1) The Assistant... functions. (c) In FAS Regions, the Assistant Regional Commissioner or designee. Contracting officer's...

48 CFR 502.101 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Acquisition Service (FAS), a director of a Central Office or Regional office Division responsible for performing contracting or contract administration functions. (b) In FAS Central Office— (1) The Assistant... functions. (c) In FAS Regions, the Assistant Regional Commissioner or designee. Contracting officer's...

48 CFR 502.101 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Acquisition Service (FAS), a director of a Central Office or Regional office Division responsible for performing contracting or contract administration functions. (b) In FAS Central Office— (1) The Assistant... functions. (c) In FAS Regions, the Assistant Regional Commissioner or designee. Contracting officer's...

48 CFR 502.101 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Acquisition Service (FAS), a director of a Central Office or Regional office Division responsible for performing contracting or contract administration functions. (b) In FAS Central Office— (1) The Assistant... functions. (c) In FAS Regions, the Assistant Regional Commissioner or designee. Contracting officer's...

48 CFR 502.101 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Acquisition Service (FAS), a director of a Central Office or Regional office Division responsible for performing contracting or contract administration functions. (b) In FAS Central Office— (1) The Assistant... functions. (c) In FAS Regions, the Assistant Regional Commissioner or designee. Contracting officer's...

Modeling Seasonal Influenza Transmission and Its Association with Climate Factors in Thailand Using Time-Series and ARIMAX Analyses.

PubMed

Chadsuthi, Sudarat; Iamsirithaworn, Sopon; Triampo, Wannapong; Modchang, Charin

2015-01-01

Influenza is a worldwide respiratory infectious disease that easily spreads from one person to another. Previous research has found that the influenza transmission process is often associated with climate variables. In this study, we used autocorrelation and partial autocorrelation plots to determine the appropriate autoregressive integrated moving average (ARIMA) model for influenza transmission in the central and southern regions of Thailand. The relationships between reported influenza cases and the climate data, such as the amount of rainfall, average temperature, average maximum relative humidity, average minimum relative humidity, and average relative humidity, were evaluated using cross-correlation function. Based on the available data of suspected influenza cases and climate variables, the most appropriate ARIMA(X) model for each region was obtained. We found that the average temperature correlated with influenza cases in both central and southern regions, but average minimum relative humidity played an important role only in the southern region. The ARIMAX model that includes the average temperature with a 4-month lag and the minimum relative humidity with a 2-month lag is the appropriate model for the central region, whereas including the minimum relative humidity with a 4-month lag results in the best model for the southern region.

Genetic potential of black bean genotypes with predictable behaviors in multienvironment trials.

PubMed

Torga, P P; Melo, P G S; Pereira, H S; Faria, L C; Melo, L C

2016-10-24

The aim of this study was to evaluate the phenotypic stability and specific and broad adaptability of common black bean genotypes for the Central and Center-South regions of Brazil by using the Annicchiarico and AMMI (weighted average of absolute scores: WAAS, and weighted average of absolute scores and productivity: WAASP) methodologies. We carried out 69 trials, with 43 and 26 trials in the Central and Center-South regions, respectively. Thirteen genotypes were evaluated in a randomized block design with three replications, during the rainy, dry, and winter seasons in 2 years. To obtain estimates of specific adaptation, we analyzed the parameters for each method obtained in the two geographic regions separately. To estimate broad adaptation, we used the average of the parameters obtained from each region. The lines identified with high specific adaptation in each region were not the same based on the Annicchiarico and AMMI (WAAS) methodologies. It was not possible to identify the same genotypes with specific or broad stability by using these methods. By contrast, the Annicchiarico and AMMI (WAASP) methods presented very similar estimates of broad and specific adaptation. Based on these methods, the lines with more specific adaptation were CNFP 8000 and CNFP 7994, in the Central and Center-South regions, respectively, of which the CNFP 8000 line was more widely adapted.

Identification of a Fourth Haplotype of Bactericera cockerelli (Hemiptera: Triozidae) in the United States

PubMed Central

Swisher, Kylie D.; Henne, Donald C.; Crosslin, James M.

2014-01-01

Abstract The potato psyllid, Bactericera cockerelli (Sulc) (Hemiptera: Triozidae), is a pest of potato and other solanaceous crops in North and Central America and New Zealand. Previous genotyping studies have demonstrated the presence of three different haplotypes of B. cockerelli in the United States corresponding to three geographical regions: Central, Western, and Northwestern. These studies utilized psyllids collected in the western and central United States between 1998 and 2011. In an effort to further genotype potato psyllids collected in the 2012 growing season, a fourth B. cockerelli haplotype was discovered corresponding to the Southwestern United States geographical region. High-resolution melting analyses identified this new haplotype using an amplicon generated from a portion of the B. cockerelli mitochondrial cytochrome coxidase subunit I gene. Sequencing of this gene, as well as use of a restriction enzyme assay, confirmed the identification of the novel B. cockerelli haplotype in the United States. PMID:25368079

Triggered earthquakes and the 1811-1812 New Madrid, central United States, earthquake sequence

USGS Publications Warehouse

Hough, S.E.

2001-01-01

The 1811-1812 New Madrid, central United States, earthquake sequence included at least three events with magnitudes estimated at well above M 7.0. I discuss evidence that the sequence also produced at least three substantial triggered events well outside the New Madrid Seismic Zone, most likely in the vicinity of Cincinnati, Ohio. The largest of these events is estimated to have a magnitude in the low to mid M 5 range. Events of this size are large enough to cause damage, especially in regions with low levels of preparedness. Remotely triggered earthquakes have been observed in tectonically active regions in recent years, but not previously in stable continental regions. The results of this study suggest, however, that potentially damaging triggered earthquakes may be common following large mainshocks in stable continental regions. Thus, in areas of low seismic activity such as central/ eastern North America, the hazard associated with localized source zones might be more far reaching than previously recognized. The results also provide additional evidence that intraplate crust is critically stressed, such that small stress changes are especially effective at triggering earthquakes.

Regional cyst concentration as a prognostic biomarker for polycystic kidney disease

NASA Astrophysics Data System (ADS)

Warner, Joshua D.; Irazabal, Maria V.; Torres, Vicente E.; King, Bernard F.; Erickson, Bradley J.

2014-03-01

Polycystic kidney disease (PKD) is a major cause of renal failure. Despite recent advances in understanding the biochemistry and genetics of PKD, the functional mechanisms underpinning the declines in renal function observed in the disorder are not well established. No studies investigating the distribution of cysts within polycystic kidneys exist. This work introduces regional cyst concentration as a new biomarker for evaluation of patients suffering from PKD. We derive a method to define central and peripheral regions of the kidney, approximating the anatomical division between cortex and medulla, and apply it to two cohorts of ten patients with early/mild or late/severe disease. Our results from the late/severe cohort show peripheral cyst concentration correlates with the current standard PKD biomarker, total kidney volume (TKV), signi cantly better than central cyst concentration (p < 0.05). We also find that cyst concentration was globally increased in the late/severe cohort (p << 0.01) compared to the early/mild cohort, for both central and peripheral regions. These findings show cysts in PKD are not distributed homogeneously throughout the renal tissues.

Ground cover in old-growth forests of the central hardwood region

Treesearch

Martin A. Spetich; Stephen R. Shifley; George R. Parker; Felix, Jr. Ponder

1997-01-01

Differences in ground cover (percent cover of litter, percent cover of vegetation and litter weight) in old-growth forests across this region are not well understood. We initiated a long-term study in a three-state region to enhance knowledge in this area. We present baseline results for ground cover and compare these data across productivity regions. Thirty 0.25-ac (0...

Atmospheric Transport of Arid Aerosol from Desert Regions of Central Asia

NASA Astrophysics Data System (ADS)

Chen, Boris; Solomon, Paul; Sitnov, Sergei; Grechko, Evgeny; Maximenkov, Leonid; Artamonova, Maria; Pogarski, Fedor

2010-05-01

Investigation of atmospheric transport of arid aerosol from Central Asia was held within the ISTC project 3715. Particular attention was paid to the removal of aerosol from the Aral Sea region and its further transport, because aerosol and pollutants emission from Central Asia affect the airspace of the entire Asian continent. At the same time measurements of aerosols in the atmosphere of Central Asia are holding in a small number of stations, and currently available data are insufficient to define the initial conditions and/or verification of models of long-range transport. To identify sources of pollution transported from Central Asia, in Kyrgyzstan measurement and sampling of air were organized: at the station on the northern slope of the Kirgiz Range, 30 km south of Bishkek, at an altitude of 1700 m above sea level (Bishkek Site, 42,683N; 74,694E ), and on permanent alpine Teploklyuchenka lidar station in the Central Tien Shan at an altitude of 2000 m above sea level (Lidar Site, 42,467N; 78,533E). The chemical analysis of collected aerosol and soils samples was carried out. Measurements of aerosol at these stations have been merged with the simulation of the trajectories of air masses in the study region and with the satellite (the Terra and Aqua satellites) observations of aerosol optical thickness in this region. Satellite data for the region 43-47 N, and 58-62 E (Aral Sea) from April 2008 to September 2009 were analyzed. The moments were selected, when the value of aerosol optical thickness (AOT) was greatest (more than 0.5), and the transport from the Aral Sea region to the observation sites took place. For each of these days, the forward trajectories, which started at 6 points within the region, were calculated using the HYSPLIT model. The days, on which the trajectories reached the BISHKEK and LIDAR sites, were determined from the data obtained. Calculations on the basis of the RAMS model were performed for these days. These calculations were performed using a grid of 160*120*30 points. The obtained meteorological fields were used in the HYPACT model; the source of Lagrangian particles was located over the Aral Sea region. As the result for 2008 11 days were detected when aerosol from the Aral Sea was actively transported to the observation sites. Comparative chemical analysis of aerosol samples at the stations of observation and soil samples from the Aral Sea region would confirm the presence of emissions and regional transport. It should be noted that the main source of aerosol in Central Asia is Taklamakan desert. Average value and AOT variability over it several times higher than corresponding AOT values over the rest of the region. The greatest variability aerosol over Taklamakan observed from late March to mid-May. For example, on April 22, 2008 average of the AOT in cell 5° x 5° over the western part of Taklamakan - value reached 3,171. AOT virtually throughout the region positively correlated with AOT over Taklamakan desert. The most noticeable effect makes an aerosol of Taklamakan found in the south-east Kyrgyzstan, Tajikistan in the east and north of the Tibetan highlands. The impact of the Aral Sea area is restricted significantly less. In doing so, AOT in the central part of the region reveals a weak negative correlation with the AOT over the Aral Sea.

Multiregional input-output model for the evaluation of Spanish water flows.

PubMed

Cazcarro, Ignacio; Duarte, Rosa; Sánchez Chóliz, Julio

2013-01-01

We construct a multiregional input-output model for Spain, in order to evaluate the pressures on the water resources, virtual water flows, and water footprints of the regions, and the water impact of trade relationships within Spain and abroad. The study is framed with those interregional input-output models constructed to study water flows and impacts of regions in China, Australia, Mexico, or the UK. To build our database, we reconcile regional IO tables, national and regional accountancy of Spain, trade and water data. Results show an important imbalance between origin of water resources and final destination, with significant water pressures in the South, Mediterranean, and some central regions. The most populated and dynamic regions of Madrid and Barcelona are important drivers of water consumption in Spain. Main virtual water exporters are the South and Central agrarian regions: Andalusia, Castile-La Mancha, Castile-Leon, Aragon, and Extremadura, while the main virtual water importers are the industrialized regions of Madrid, Basque country, and the Mediterranean coast. The paper shows the different location of direct and indirect consumers of water in Spain and how the economic trade and consumption pattern of certain areas has significant impacts on the availability of water resources in other different and often drier regions.

Central Asia: Regional Developments and Implications for U.S. Interests

DTIC Science & Technology

2012-05-18

Representatives, Committee on International Relations, Subcommittee on the Middle East and Central Asia, Assessing Energy and Security Issues in Central Asia...Akiner, Violence in Andijon, 13 May 2005: An Independent Assessment , Central Asia-Caucasus Institute, July 2005; AbduMannob Polat, Reassessing Andijan...observers warn that Islamic extremism could increase dramatically in the region, others discount the risk that the existing secular governments soon

Central Hardwoods ecosystem vulnerability assessment and synthesis: a report from the Central Hardwoods Climate Change Response Framework project

Treesearch

Leslie Brandt; Hong He; Louis Iverson; Frank R. Thompson; Patricia Butler; Stephen Handler; Maria Janowiak; P. Danielle Shannon; Chris Swanston; Matthew Albrecht; Richard Blume-Weaver; Paul Deizman; John DePuy; William D. Dijak; Gary Dinkel; Songlin Fei; D. Todd Jones-Farrand; Michael Leahy; Stephen Matthews; Paul Nelson; Brad Oberle; Judi Perez; Matthew Peters; Anantha Prasad; Jeffrey E. Schneiderman; John Shuey; Adam B. Smith; Charles Studyvin; John M. Tirpak; Jeffery W. Walk; Wen J. Wang; Laura Watts; Dale Weigel; Steve Westin

2014-01-01

The forests in the Central Hardwoods Region will be affected directly and indirectly by a changing climate over the next 100 years. This assessment evaluates the vulnerability of terrestrial ecosystems in the Central Hardwoods Region of Illinois, Indiana, and Missouri to a range of future climates. Information on current forest conditions, observed climate trends,...

Regional analysis of hardwood lumber production: 1963 - 2005

Treesearch

William Luppold; Matthew Bumgardner

2008-01-01

Between 1963 and 2005 hardwood lumber production in the eastern United States increased by more than 50%. Production more than doubled in the northeastern and north central regions while increasing by less than 25% in the southeastern and south central regions. Increased lumber production in the northern regions was facilitated by an expanding sawtimber inventory,...

Amodal processing in human prefrontal cortex.

PubMed

Tamber-Rosenau, Benjamin J; Dux, Paul E; Tombu, Michael N; Asplund, Christopher L; Marois, René

2013-07-10

Information enters the cortex via modality-specific sensory regions, whereas actions are produced by modality-specific motor regions. Intervening central stages of information processing map sensation to behavior. Humans perform this central processing in a flexible, abstract manner such that sensory information in any modality can lead to response via any motor system. Cognitive theories account for such flexible behavior by positing amodal central information processing (e.g., "central executive," Baddeley and Hitch, 1974; "supervisory attentional system," Norman and Shallice, 1986; "response selection bottleneck," Pashler, 1994). However, the extent to which brain regions embodying central mechanisms of information processing are amodal remains unclear. Here we apply multivariate pattern analysis to functional magnetic resonance imaging (fMRI) data to compare response selection, a cognitive process widely believed to recruit an amodal central resource across sensory and motor modalities. We show that most frontal and parietal cortical areas known to activate across a wide variety of tasks code modality, casting doubt on the notion that these regions embody a central processor devoid of modality representation. Importantly, regions of anterior insula and dorsolateral prefrontal cortex consistently failed to code modality across four experiments. However, these areas code at least one other task dimension, process (instantiated as response selection vs response execution), ensuring that failure to find coding of modality is not driven by insensitivity of multivariate pattern analysis in these regions. We conclude that abstract encoding of information modality is primarily a property of subregions of the prefrontal cortex.

Regional variation in smoking among African Americans.

PubMed

King, G; Polednak, A P; Bendel, R

1999-08-01

The impact of geographic region and metropolitan residence on smoking prevalence among African Americans has not been adequately examined. This study analyzed 5 years of data from the National Health Interview Survey (1990-1994) on current smoking and regional variation among 16,738 African Americans. Results. Respondents in the West had the lowest unadjusted smoking prevalence rates and Midwest residents had the highest. Current smoking was lower among African Americans living in non-central cities than in central cities even after adjusting for several sociodemographic covariates. Multivariate logistic regression analysis revealed that black women in the South were significantly less likely to be smokers compared with any other gender/region group. These findings suggest the significance of gender and regional factors such as the social history of migration, social stress and racism, exposure to tobacco advertisement, variations in cultural influences, community structures, and coping strategies in under standing African American smoking behavior. Copyright 1999 American Health Foundation and Academic Press.

Assessment of geothermal energy potential by geophysical methods: Nevşehir Region, Central Anatolia

NASA Astrophysics Data System (ADS)

Kıyak, Alper; Karavul, Can; Gülen, Levent; Pekşen, Ertan; Kılıç, A. Rıza

2015-03-01

In this study, geothermal potential of the Nevşehir region (Central Anatolia) was assessed by using vertical electrical sounding (VES), self-potential (SP), magnetotelluric (MT), gravity and gravity 3D Euler deconvolution structure analysis methods. Extensive volcanic activity occurred in this region from Upper Miocene to Holocene time. Due to the young volcanic activity Nevşehir region can be viewed as a potential geothermal area. We collected data from 54 VES points along 5 profiles, from 28 MT measurement points along 2 profiles (at frequency range between 320 and 0.0001 Hz), and from 4 SP profiles (total 19 km long). The obtained results based on different geophysical methods are consistent with each other. Joint interpretation of all geological and geophysical data suggests that this region has geothermal potential and an exploration well validated this assessment beyond doubt.

Central Asian Republics: A Case Study for Medical Education Reform

ERIC Educational Resources Information Center

Conaboy, Kathleen A.; Nugmanova, Zhamilya; Yeguebaeva, Saltanat; Jaeger, Frances; Daugherty, Robert M.

2005-01-01

Social, political, and economic changes in the former Soviet Union precipitated both the collapse of a once-centralized medical education system in the region and the development of individual models in its place. In the context of rapid globalization and international concerns about health, this development of "nation-based" models for…

Chilocorus stigma (Coleoptera: Coccinellidae) and other predators of beech scale in central New York

Treesearch

Mark Mayer; Douglas C. Allen

1983-01-01

The twice-stabbed lady beetle Chilocorus stigma (Say), was studied in two infestations of beech scale, Cryptococccus fagisuga Lind., to elucidate predator biology and to determine the predator's effect on scale populations. C. stigma is univoltine in north-central regions of New York and its seasonal...

Regional variation in epiphytic macrolichen communities in northern and central California forests

Treesearch

Sarah Jovan; Bruce McCune

2004-01-01

We studied epiphytic macrolichen communities in northern and central California to 1) describe how gradients in community composition relate to climate, topography, and stand structure and 2) define subregions of relatively homogeneous lichen communities and environmental conditions. Non-metric multidimensional scaling was used to characterize landscape-level trends in...

Centralized Workshops in Singapore. Education and Work 1.

ERIC Educational Resources Information Center

Singh, P. Harbans

First in an education and work series on innovative vocational training programs in Asian countries, this booklet describes the program in Singapore of integrating technical studies with general education at the lower secondary level through centralized workshops that provide training for students from all types of secondary schools in a region.…

NASA LCLUC Program: An Integrated Forest Monitoring System for Central Africa

NASA Technical Reports Server (NTRS)

Laporte, Nadine; LeMoigne, Jacqueline; Elkan, Paul; Desmet, Olivier; Paget, Dominique; Pumptre, Andrew; Gouala, Patrice; Honzack, Miro; Maisels, Fiona

2004-01-01

Central Africa has the second largest unfragmented block of tropical rain forest in the world; it is also one of the largest carbon and biodiversity reservoirs. With nearly one-third of the forest currently allocated for logging, the region is poised to undergo extensive land-use change. Through the mapping of the forests, our Integrated Forest Monitoring System for Central Africa (INFORMS) project aims to monitor habitat alteration, support biodiversity conservation, and promote better land-use planning and forest management. Designed as an interdisciplinary project, its goal is to integrate data acquired from satellites with field observations from forest inventories, wildlife surveys, and socio-economic studies to map and monitor forest resources. This project also emphasizes on collaboration and coordination with international, regional, national, and local partners-including non-profit, governmental, and commercial sectors. This project has been focused on developing remote sensing products for the needs of forest conservation and management, insuring that research findings are incorporated in forest management plans at the national level. The societal impact of INFORMS can be also appreciated through the development of a regional remote sensing network in central Africa. With a regional office in Kinshasa, (www.OSFAC.org), the contribution to the development of forest management plans for 1.5 million hectares of forests in northern Republic of Congo (www.tt-timber.com), and the monitoring of park encroachments in the Albertine region (Uganda and DRC) (www.albertinerift.org).

A modeling study of the role of deforestation on the climate of central and eastern Africa

DOE Office of Scientific and Technical Information (OSTI.GOV)

Semazzi, F.H.M.; Sun, Liqiang; Giorgi, F.

1997-11-01

This study assessed the effects of deforestation on the physical climate system of eastern and central Africa. The model used was the regional climate model (RegCM2) developed at the National Center for Atmospheric Research, and customized for the region under study. In the anomaly simulation, the land cover was systematically altered to replace the tropical forest with grass and Savannah cover. The RegCM2 realistically simulated the main features of the climate over eastern and central Africas. It was found that: (1) the rainfall dramatically decreased in 2 subregions, decreased in two subregions, increased in 1 subregion, and remained the samemore » in 1 subregion; (2) rainfall deficit mainly happened during night time over the TF subregion and daytime over the LV subregion; and (3) mean surface air temperature increased over 5 subregions and decreased in 1 subregions. Deforestation also increased the diurnal variation of surface air temperature over one subregion. 12 refs., 2 figs., 3 tabs.« less

Tree biomass in the North Central Region.

Treesearch

Gerhard K. Raile; Pamela J. Jakes

1982-01-01

Methods for calculating tree biomass are outlined, and the biomass on commercial forest land is estimated for 11 north-central states. Tree biomass in the North Central Region totals 3.6 billion tons, or 50 tons per commercial forest acre. For all species, total tree biomass is concentrated in growing-stock boles.

Hierarchical modeling of genome-wide Short Tandem Repeat (STR) markers infers native American prehistory.

PubMed

Lewis, Cecil M

2010-02-01

This study examines a genome-wide dataset of 678 Short Tandem Repeat loci characterized in 444 individuals representing 29 Native American populations as well as the Tundra Netsi and Yakut populations from Siberia. Using these data, the study tests four current hypotheses regarding the hierarchical distribution of neutral genetic variation in native South American populations: (1) the western region of South America harbors more variation than the eastern region of South America, (2) Central American and western South American populations cluster exclusively, (3) populations speaking the Chibchan-Paezan and Equatorial-Tucanoan language stock emerge as a group within an otherwise South American clade, (4) Chibchan-Paezan populations in Central America emerge together at the tips of the Chibchan-Paezan cluster. This study finds that hierarchical models with the best fit place Central American populations, and populations speaking the Chibchan-Paezan language stock, at a basal position or separated from the South American group, which is more consistent with a serial founder effect into South America than that previously described. Western (Andean) South America is found to harbor similar levels of variation as eastern (Equatorial-Tucanoan and Ge-Pano-Carib) South America, which is inconsistent with an initial west coast migration into South America. Moreover, in all relevant models, the estimates of genetic diversity within geographic regions suggest a major bottleneck or founder effect occurring within the North American subcontinent, before the peopling of Central and South America. 2009 Wiley-Liss, Inc.

Ethanol and corticotropin releasing factor receptor modulation of central amygdala neurocircuitry: An update and future directions.

PubMed

Silberman, Yuval; Winder, Danny G

2015-05-01

The central amygdala is a critical brain region for many aspects of alcohol dependence. Much of the work examining the mechanisms by which the central amygdala mediates the development of alcohol dependence has focused on the interaction of acute and chronic ethanol with central amygdala corticotropin releasing factor signaling. This work has led to a great deal of success in furthering the general understanding of central amygdala neurocircuitry and its role in alcohol dependence. Much of this work has primarily focused on the hypothesis that ethanol utilizes endogenous corticotropin releasing factor signaling to upregulate inhibitory GABAergic transmission in the central amygdala. Work that is more recent suggests that corticotropin releasing factor also plays an important role in mediating anxiety-like behaviors via the enhancement of central amygdala glutamatergic transmission, implying that ethanol/corticotropin releasing factor interactions may modulate excitatory neurotransmission in this brain region. In addition, a number of studies utilizing optogenetic strategies or transgenic mouse lines have begun to examine specific central amygdala neurocircuit dynamics and neuronal subpopulations to better understand overall central amygdala neurocircuitry and the role of neuronal subtypes in mediating anxiety-like behaviors. This review will provide a brief update on this literature and describe some potential future directions that may be important for the development of better treatments for alcohol addiction. Copyright © 2015 Elsevier Inc. All rights reserved.

Trait-Related Cortical-Subcortical Dissociation in Bipolar Disorder: Analysis of Network Degree Centrality.

PubMed

Zhou, Qian; Womer, Fay Y; Kong, Lingtao; Wu, Feng; Jiang, Xiaowei; Zhou, Yifang; Wang, Dahai; Bai, Chuan; Chang, Miao; Fan, Guoguang; Xu, Ke; He, Yong; Tang, Yanqing; Wang, Fei

2017-05-01

Bipolar disorder is a systemic brain disorder. Accumulated evidence suggested that cortical-subcortical imbalance could be a trait-related pathogenic factor of bipolar disorder. Degree centrality, a robust index of focal connectivity in which the number of direct connections from one node to all nodes is counted, has not previously been studied in bipolar disorder as a whole. Resting state functional magnetic resonance imaging was performed on 52 patients with DSM-IV bipolar I disorder and 70 healthy controls recruited between September 2009 and July 2014. Degree centrality was calculated within cerebral gray matter for each subject and compared between patients with bipolar disorder and healthy controls. Hub distributions of both groups were explored. Effects of medication exposure and mood state on degree centrality, as well as cortical-subcortical degree centrality correlations, were explored. Compared to healthy controls, patients with bipolar disorder exhibited significant decrease in degree centrality in cortical regions, including the middle temporal pole, inferior temporal gyrus, and ventral prefrontal cortex, but showed significant increase in degree centrality mainly in subcortical regions, including caudate, thalamus, parahippocampal gyrus, hippocampi, anterior cingulate, insula, and amygdala, and a small portion of cortical regions, such as superior and middle frontal gyrus (P < .05, corrected). Spatial distributions of the 2 groups were very similar. No significant effects of medication exposure or mood state on degree centrality were found. Patients with bipolar disorder also showed significant decrease in cortical-subcortical degree centrality correlation (P = .003). These findings further contribute to the mounting evidence of cortical-subcortical dissociation in bipolar disorder pathophysiology. In addition, this study supports the continued development and implementation of graph-based techniques to enhance our understanding of the underlying neural mechanisms in mental disorders such as bipolar disorder, which are increasingly viewed as systemic brain disorders rather than disorders arising from disruption within a single structure or a limited number of structures. Due to the heterogeneity of our sample, as well as the small sample size of each medication and mood state subgroups, further investigation is needed to support our findings. © Copyright 2016 Physicians Postgraduate Press, Inc.

A Study of Policy, Organisation and Provision in Community Education and Leisure and Recreation in Three Scottish Regions.

ERIC Educational Resources Information Center

Alexander, D. J.; And Others

This document describes a study conducted to examine the effectiveness and efficiency of the provision of leisure and recreation services and community education services in selected areas of the Tayside, Central, and Fife Regions of Scotland. The 18-month-long study gathered 826 responses from 1,060 questionnaires issued in order to study the…

The impact of HTA and procurement practices on the selection and prices of medical devices.

PubMed

Callea, Giuditta; Armeni, Patrizio; Marsilio, Marta; Jommi, Claudio; Tarricone, Rosanna

2017-02-01

Technological innovation in healthcare yields better health outcomes but also drives healthcare expenditure, and governments are struggling to maintain an appropriate balance between patient access to modern care and the economic sustainability of healthcare systems. Health Technology Assessment (HTA) and centralized procurement are increasingly used to govern the introduction and diffusion of new technologies in an effort to make access to innovation financially sustainable. However, little empirical evidence is available to determine how they affect the selection of new technologies and unit prices. This paper focuses on medical devices (MDs) and investigates the combined effect of various HTA governance models and procurement practices on the two steps of the MD purchasing process (i.e., selecting the product and setting the unit price). Our analyses are based on primary data collected through a national survey of Italian public hospitals. The Italian National Health Service is an ideal case study because it is highly decentralized and because regions have adopted different HTA governance models (i.e., regional, hospital-based, double-level or no HTA), often in combination with centralized regional procurement programs. Hence, the Italian case allows us to test the impact of different combinations of HTA models and procurement programs in the various regions. The results show that regional HTA increases the probability of purchasing the costliest devices, whereas hospital-based HTA functions more like a cost-containment unit. Centralized regional procurement does not significantly affect MD selection and is associated with a reduction in the MD unit price: on average, hospitals located in regions with centralized procurement pay 10.1% less for the same product. Hospitals located in regions with active regional HTA programs pay higher prices for the same device (+23.2% for inexpensive products), whereas hospitals that have developed internal HTA programs pay 8.3% on average more for the same product. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Genetic Factors and Orofacial Motor Learning Selectively Influence Variability in Central Sulcus Morphology in Chimpanzees (Pan troglodytes)

PubMed Central

Autrey, Michelle; Mahovetz, Lindsay; Pope, Sarah; Mareno, Mary Catherine; Schapiro, Steven J.

2017-01-01

Captive chimpanzees (Pan troglodytes) have been shown to learn the use of novel attention-getting (AG) sounds to capture the attention of humans as a means of requesting or drawing their attention to a desired object or food. There are significant individual differences in the use of AG sounds by chimpanzees and, here, we examined whether changes in cortical organization of the central sulcus (CS) were associated with AG sound production. MRI scans were collected from 240 chimpanzees, including 122 that reliably produced AG sounds and 118 that did not. For each subject, the depth of CS was quantified along the superior–inferior plane with specific interest in the inferior portion corresponding to the region of the motor cortex where the mouth and orofacial movements are controlled. Results indicated that CS depth in the inferior, but not superior, portion was significantly greater in chimpanzees that reliably produced AG sounds compared with those who did not. Quantitative genetic analyses indicated that overall CS surface area and depth were significantly heritable, particularly in the superior regions, but less so in the inferior and central portions. Further, heritability in CS depth was altered as a function of acquisition of AG sounds. The collective results suggest that learning to produce AG sounds resulted in region-specific cortical reorganization within the inferior portion of the CS, a finding previously undocumented in chimpanzees or any nonhuman primate. SIGNIFICANCE STATEMENT Recent studies in chimpanzees (Pan troglodytes) have shown that some can learn to produce novel sounds by configuring different orofacial movement patterns and these sounds are used in communicatively relevant contexts. Here, we examined the neuromorphological correlates in the production of these sounds in chimpanzees. We show that chimpanzees that have learned to produce these sounds show significant differences in central sulcus (CS) morphology, particularly in the inferior region. We further show that overall CS morphology and regions within the superior portion are significantly heritable, whereas central and inferior portions of the CS are not. The collective findings suggest chimpanzees exhibit cortical plasticity in regions of the brain that were central to the emergence of speech functions in humans. PMID:28473646

Central Asia: Regional Developments and Implications for U.S. Interests

DTIC Science & Technology

2012-01-03

Central Asia, Assessing Energy and Security Issues in Central Asia, Testimony of Steven Mann, Principal Deputy Assistant Secretary for South and...Akiner, Violence in Andijon, 13 May 2005: An Independent Assessment , Central Asia-Caucasus Institute, July 2005; AbduMannob Polat, Reassessing Andijan...dramatically in the region, others discount the risk that the existing secular governments soon will be overthrown by Islamic extremists.57 In the case

Central New York Library Resources Council CLRC Regional Digitization Plan. Final Report for the Preparing Central New York History for the Future LSTA Project.

ERIC Educational Resources Information Center

Sywetz, Betsy

The primary goal for digitization projects sponsored by the Central New York Library Resources Council (CLRC) is enhanced access for the people of the region to digital resources created from collections in Central New York's libraries, archives and museums. The CLRC Digitization Plan provides a framework for the support of digitization activities…

Receiver function images of the central Chugoku region in the Japanese islands using Hi-net data

NASA Astrophysics Data System (ADS)

Ramesh, D. S.; Wakatsu, H. K.; Watada, S.; Yuan, X.

2005-04-01

Crustal configuration of the central Chugoku region with disposition of the Philippine Sea Plate (PHS) in this area are investigated through the receiver function approach using short-period Hi-net data. Images of the upper mantle discontinuities are also obtained. Restituted short-period receiver functions bring out discernible variations in average composition of the crust and its thickness in the study region. The Vp/ Vs values in the study area are generally high, reaching values in excess of 1.85 at a few places. The central part of the study region showing the highest Vp/ Vs values is coincidentally a subregion of least seismicity, possibly bestowed with special subsurface structure. Migrated receiver function images, both Ps and Pps images, unambiguously trace the NW subducting PHS taking a steeper plunge in the northwest part of the Chugoku region reaching depths of 70 km from its low dip disposition in the southeast. An excellent correlation of the subducting PHS with the hypocenters is also seen. We demonstrate that short-period data after restitution and application of appropriate low pass filters can indeed detect presence of the global 410-km and 660-km discontinuities and map their disposition reasonably well. Our migrated receiver functions image the deflections in the 410-km and 660-km discontinuities in an anti-correlated fashion on expected lines of Clapeyron slope predictions induced by subduction of the Pacific plate (PAC) beneath Japanese islands, though PAC itself is feebly traced but shows good correlation with slab seismicity.

A Nonlinear Inversion Approach to Map the Magnetic Basement: A Case Study from Central India Using Aeromagnetic Data

NASA Astrophysics Data System (ADS)

Kumar, R.; Bansal, A. R.; Anand, S. P.; Rao, V. K.; Singh, U. K.

2016-12-01

The central India region is having complex geology covering various geological units e.g., Precambrian Bastar Craton (including Proterozoic Chhattisgarh Basin, granitic intrusions etc.) and Eastern Ghat Mobile Belt, Gondwana Godavari and Mahanadi Grabens, Late Cretaceous Deccan Traps etc. The central India is well covered by reconnaissance scale aeromagnetic data. We analyzed this data for mapping the basement by dividing into143 overlapping blocks of 100×100km using least square nonlinear inversion method for fractal distribution of sources. The scaling exponents and depth values are optimized using grid search method. We interpreted estimated depths of anomalous sources as magnetic basement and shallow anomalous magnetic sources. The shallow magnetic anomalies are found to vary from 1 to 3km whereas magnetic basement depths are found to vary from 2km to 7km. The shallowest basement depth of 2km found corresponding to Kanker granites a part of Bastar Craton whereas deepest basement depth of 7km is associated with Godavari Graben and south eastern part of Eastern Ghat Mobile Belts near the Parvatipuram Bobbili fault. The variation of magnetic basement, shallow depths and scaling exponent in the region indicate complex tectonic, heterogeneity and intrusive bodies at different depths which is due to different tectonic processes in the region. The detailed basement depth of central India is presented in this study.

Potential effects of climate change on streamflow for seven watersheds in eastern and central Montana

USGS Publications Warehouse

Chase, Katherine J.; Haj, Adel E.; Regan, R. Steven; Viger, Roland J.

2016-01-01

Study regionEastern and central Montana.Study focusFish in Northern Great Plains streams tolerate extreme conditions including heat, cold, floods, and drought; however changes in streamflow associated with long-term climate change may render some prairie streams uninhabitable for current fish species. To better understand future hydrology of these prairie streams, the Precipitation-Runoff Modeling System model and output from the RegCM3 Regional Climate model were used to simulate streamflow for seven watersheds in eastern and central Montana, for a baseline period (water years 1982–1999) and three future periods: water years 2021–2038 (2030 period), 2046–2063 (2055 period), and 2071–2088 (2080 period).New hydrological insights for the regionProjected changes in mean annual and mean monthly streamflow vary by the RegCM3 model selected, by watershed, and by future period. Mean annual streamflows for all future periods are projected to increase (11–21%) for two of the four central Montana watersheds: Middle Musselshell River and Cottonwood Creek. Mean annual streamflows for all future periods are projected to decrease (changes of −24 to −75%) for Redwater River watershed in eastern Montana. Mean annual streamflows are projected to increase slightly (2–15%) for the 2030 period and decrease (changes of −16 to −44%) for the 2080 period for the four remaining watersheds.

Sex differences in the influence of body mass index on anatomical architecture of brain networks.

PubMed

Gupta, A; Mayer, E A; Hamadani, K; Bhatt, R; Fling, C; Alaverdyan, M; Torgerson, C; Ashe-McNalley, C; Van Horn, J D; Naliboff, B; Tillisch, K; Sanmiguel, C P; Labus, J S

2017-08-01

The brain has a central role in regulating ingestive behavior in obesity. Analogous to addiction behaviors, an imbalance in the processing of rewarding and salient stimuli results in maladaptive eating behaviors that override homeostatic needs. We performed network analysis based on graph theory to examine the association between body mass index (BMI) and network measures of integrity, information flow and global communication (centrality) in reward, salience and sensorimotor regions and to identify sex-related differences in these parameters. Structural and diffusion tensor imaging were obtained in a sample of 124 individuals (61 males and 63 females). Graph theory was applied to calculate anatomical network properties (centrality) for regions of the reward, salience and sensorimotor networks. General linear models with linear contrasts were performed to test for BMI and sex-related differences in measures of centrality, while controlling for age. In both males and females, individuals with high BMI (obese and overweight) had greater anatomical centrality (greater connectivity) of reward (putamen) and salience (anterior insula) network regions. Sex differences were observed both in individuals with normal and elevated BMI. In individuals with high BMI, females compared to males showed greater centrality in reward (amygdala, hippocampus and nucleus accumbens) and salience (anterior mid-cingulate cortex) regions, while males compared to females had greater centrality in reward (putamen) and sensorimotor (posterior insula) regions. In individuals with increased BMI, reward, salience and sensorimotor network regions are susceptible to topological restructuring in a sex-related manner. These findings highlight the influence of these regions on integrative processing of food-related stimuli and increased ingestive behavior in obesity, or in the influence of hedonic ingestion on brain topological restructuring. The observed sex differences emphasize the importance of considering sex differences in obesity pathophysiology.

Sex Differences in the Influence of Body Mass Index on Anatomical Architecture of Brain Networks

PubMed Central

Gupta, Arpana; Mayer, Emeran A.; Hamadani, Kareem; Bhatt, Ravi; Fling, Connor; Alaverdyan, Mher; Torgenson, Carinna; Ashe-McNalley, Cody; Van Horn, John D; Naliboff, Bruce; Tillisch, Kirsten; Sanmiguel, Claudia P.; Labus, Jennifer S.

2017-01-01

Background/Objective The brain plays a central role in regulating ingestive behavior in obesity. Analogous to addiction behaviors, an imbalance in the processing of rewarding and salient stimuli results in maladaptive eating behaviors that override homeostatic needs. We performed network analysis based on graph theory to examine the association between body mass index (BMI) and network measures of integrity, information flow, and global communication (centrality) in reward, salience and sensorimotor regions, and to identify sex-related differences in these parameters. Subjects/Methods Structural and diffusion tensor imaging were obtained in a sample of 124 individuals (61 males and 63 females). Graph theory was applied to calculate anatomical network properties (centrality) for regions of the reward, salience, and sensorimotor networks. General linear models with linear contrasts were performed to test for BMI and sex-related differences in measures of centrality, while controlling for age. Results In both males and females, individuals with high BMI (obese and overweight) had greater anatomical centrality (greater connectivity) of reward (putamen) and salience (anterior insula) network regions. Sex differences were observed both in individuals with normal and elevated BMI. In individuals with high BMI, females compared to males showed greater centrality in reward (amygdala, hippocampus, nucleus accumbens) and salience (anterior mid cingulate cortex) regions, while males compared to females had greater centrality in reward (putamen) and sensorimotor (posterior insula) regions. Conclusions In individuals with increased BMI, reward, salience, and sensorimotor network regions are susceptible to topological restructuring in a sex related manner. These findings highlight the influence of these regions on integrative processing of food-related stimuli and increased ingestive behavior in obesity, or in the influence of hedonic ingestion on brain topological restructuring. The observed sex differences emphasize the importance of considering sex differences in obesity pathophysiology. PMID:28360430

Spatial patterns of cryptobenthic coral-reef fishes in the Red Sea

NASA Astrophysics Data System (ADS)

Coker, Darren J.; DiBattista, Joseph D.; Sinclair-Taylor, Tane H.; Berumen, Michael L.

2018-03-01

Surveys to document coral-reef fish assemblages are often limited to visually conspicuous species, thus excluding a significant proportion of the biodiversity. Through standardized collections of cryptobenthic reef fishes in the central and southern Red Sea, a total of 238 species and operational taxonomic units (OTUs) from 35 families were collected. Abundance and species richness increased by 60 and 30%, respectively, from north to south, and fish community composition differed between the two regions and with proximity to shore in the central region. Models suggest regional influences in fish communities, with latitudinal patterns influenced by key coral groups ( Acropora, Pocilloporidae) and variation in environmental parameters (chlorophyll a, sea surface temperature, salinity). This study illustrates the limited taxonomic resolution in this group and in this region, and the need to expand baseline data for this under-studied assemblage. To assist in advancing this initiative, we have produced a catalogue of specimens, archived photographs, and established a DNA sequence library based on cytochrome-c oxidase subunit-I barcodes for all OTUs.

New insights on the recent and current deformation in Central-Eastern Iran, derived from a combined tectonic and GPS analysis

NASA Astrophysics Data System (ADS)

Walpersdorf, A.; Manighetti, I.; Tavakoli, F.; Mousavi, Z.; Vergnolle, M.; Jadidi, A.; Hatzfeld, D.; Aghamohammadi, A.; Djamour, Y.; Nankali, H.; Sedighi, M.; Lutz, L.

2012-04-01

We have studied the recent to current deformation in Iran and especially Central-Eastern Iran by tightly combining tectonic and GPS analyses. Based on morphotectonic analyses of satellite images, we have identified and mapped the major active faults that dissect the entire ≈ 4500 km x 2500 km2 region that extends from Eastern Turkey to Western Afghanistan/Pakistan and hence encompasses Iran, emphasizing their large-scale organization and kinematic relationships. Doing so, we have identified the major fault systems that control the tectonics of Iran, especially in its central-eastern part. We have also analyzed the 11 years GPS record on the 92 stations deployed in central-eastern Iran in the framework of the Iranian-French collaboration. The GPS analysis reveals that all major faults identified as seismogenic in central-eastern Iran are indeed currently active and slipping at fast rates. The northerly-trending East Lut, West Lut, Kuhbanan, Anar and Deshir faults have a current right-lateral slip rate of 5.7 ± 0.9, 4.7 ± 1.7, 2.3 ± 1.9, 2.7 ± 1.3 and 0.5 ± 0.2 mm/yr, respectively, while the ≈ EW-trending Doruneh and Sedeh faults have a left-lateral current slip rate of 3.1 ± 1.8 and 1.7 ± 0.2 mm/yr, respectively. The large regions bounded by the northerly-striking faults behave as fairly rigid blocks that are all found to move towards both the N13°E ARA-EUR convergence direction and the WNW, at fast rates, in the range 6.5-12.5 and 1-5 mm/yr, respectively. Combined with the available data on the studied faults, our tectonic and geodetic results suggest that a bookshelf faulting strain transfer mechanism has been and is still operating in central-eastern Iran. The coeval dextral motion of the two major, overlapping, North Anatolian-Main Recent and Caucasus-Kopeh Dagh-Herat fault lines that embrace central-eastern Iran, induces a large-scale regional sinistral shear on either side of the region, which forces the northerly-trending right-lateral faults and the blocks they bound to rotate counterclockwise in the horizontal plane. The faults and blocks have been rotating over the last ≈12 Ma, at rates reaching 1.8 °/Ma, and are still currently rotating at about these rates. We estimate the sinistral shear imposed at both edges of the central-eastern rotating zone to be in the range 2.2 - 7.2 mm/yr. The Doruneh fault likely formed more recently than the other central-eastern Iranian faults, as the imposed sinistral shear was evolving from diffuse to more localized. As a consequence, the western half of the Doruneh fault currently accommodates a significant part of the imposed regional sinistral shear. Our study thus shows that the recent to current tectonics of central-eastern Iran is not only controlled by the ARA-EUR convergence, but also by the large-scale kinematics of the adjacent plates. We finally discuss the implications of the novel strain model that we propose on the seismicity that occurs in Central-Eastern Iran.

Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.

PubMed

Jones, Harrison G; Ritschel, Tina; Pascual, Gabriel; Brakenhoff, Just P J; Keogh, Elissa; Furmanova-Hollenstein, Polina; Lanckacker, Ellen; Wadia, Jehangir S; Gilman, Morgan S A; Williamson, R Anthony; Roymans, Dirk; van 't Wout, Angélique B; Langedijk, Johannes P; McLellan, Jason S

2018-03-01

Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants and the elderly, and yet there remains no effective treatment or vaccine. The surface of the virion is decorated with the fusion glycoprotein (RSV F) and the attachment glycoprotein (RSV G), which binds to CX3CR1 on human airway epithelial cells to mediate viral attachment and subsequent infection. RSV G is a major target of the humoral immune response, and antibodies that target the central conserved region of G have been shown to neutralize both subtypes of RSV and to protect against severe RSV disease in animal models. However, the molecular underpinnings for antibody recognition of this region have remained unknown. Therefore, we isolated two human antibodies directed against the central conserved region of RSV G and demonstrated that they neutralize RSV infection of human bronchial epithelial cell cultures in the absence of complement. Moreover, the antibodies protected cotton rats from severe RSV disease. Both antibodies bound with high affinity to a secreted form of RSV G as well as to a peptide corresponding to the unglycosylated central conserved region. High-resolution crystal structures of each antibody in complex with the G peptide revealed two distinct conformational epitopes that require proper folding of the cystine noose located in the C-terminal part of the central conserved region. Comparison of these structures with the structure of fractalkine (CX3CL1) alone or in complex with a viral homolog of CX3CR1 (US28) suggests that RSV G would bind to CX3CR1 in a mode that is distinct from that of fractalkine. Collectively, these results build on recent studies demonstrating the importance of RSV G in antibody-mediated protection from severe RSV disease, and the structural information presented here should guide the development of new vaccines and antibody-based therapies for RSV.

Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies

PubMed Central

Jones, Harrison G.; Brakenhoff, Just P. J.; Furmanova-Hollenstein, Polina; Wadia, Jehangir S.; Gilman, Morgan S. A.; Roymans, Dirk

2018-01-01

Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants and the elderly, and yet there remains no effective treatment or vaccine. The surface of the virion is decorated with the fusion glycoprotein (RSV F) and the attachment glycoprotein (RSV G), which binds to CX3CR1 on human airway epithelial cells to mediate viral attachment and subsequent infection. RSV G is a major target of the humoral immune response, and antibodies that target the central conserved region of G have been shown to neutralize both subtypes of RSV and to protect against severe RSV disease in animal models. However, the molecular underpinnings for antibody recognition of this region have remained unknown. Therefore, we isolated two human antibodies directed against the central conserved region of RSV G and demonstrated that they neutralize RSV infection of human bronchial epithelial cell cultures in the absence of complement. Moreover, the antibodies protected cotton rats from severe RSV disease. Both antibodies bound with high affinity to a secreted form of RSV G as well as to a peptide corresponding to the unglycosylated central conserved region. High-resolution crystal structures of each antibody in complex with the G peptide revealed two distinct conformational epitopes that require proper folding of the cystine noose located in the C-terminal part of the central conserved region. Comparison of these structures with the structure of fractalkine (CX3CL1) alone or in complex with a viral homolog of CX3CR1 (US28) suggests that RSV G would bind to CX3CR1 in a mode that is distinct from that of fractalkine. Collectively, these results build on recent studies demonstrating the importance of RSV G in antibody-mediated protection from severe RSV disease, and the structural information presented here should guide the development of new vaccines and antibody-based therapies for RSV. PMID:29509814

The cold chain and the expanded program on immunization in Chile: an evaluation exercise.

PubMed

Carrasco, R; Dinstrans, R; Montaldo, I; Medina, E; Reyes, M; Vergara, I; Piwonka, A; Thomas, E R

1982-01-01

It was decided that a study of the cold chain should be conducted in Chile in an effort to identify situations that could be corrected and to improve the technical and administrative development of the program. Specifically, study objectives were as follows: to determine the degree to which the EPI standards for procurement, receipt, transfer, control, maintenance, and distribution of vaccines were being met; to assess the turnover, knowledge, and training of auxiliary vaccination personnel against the relevant standards established for vaccine and cold chain management; to determine the antigenic potency of measles vaccine samples available at the time visits were made to local clinics, regional health storage sites, and the central supply facility; and to test a written instrument designed for the express purpose of assessing achievement of the first 2 objectives cited. The study sought to provide a descriptive assessment of work being performed at the central, regional, and local levels in the Metropolitan Region. The operating units involved included the airport and main supply center at the central level; the 7 storage facilities of the Metropolitan Region's 78 local clinics providing maternal and child health care. 40 clinics, selected by lot, represented 51% of the region's 78 clinics and provided coverage for 49% of the population assigned to the region's health services. The units studied failed to satisfy half the investigated Expanded Program for Immunization (EPI) standards, i.e., the average achievement rating of the 3 levels combined (49.3%) fell short of half the desired 100%. The airport unit met very few of the EPI implementation standards, scoring only 20% in this area. Deficiencies were found in systems for shipping vaccine in cold boxes, for making cold rooms permanently available, and for providing adequate vaccine transportation. The central supply facility, responsible for the purchase, storage, distribution, and maintenance of an adequate vaccine stock, had an achievement score of only 41%. The regional level, represented by the 7 storage facilities studied, obtained a lower overall achievement score than the other 2 levels and appears to be a high-risk link in the cold chain. The local level, represented by the 40 clinics studied, attained the highest average achievement score of any level (57%). Yet, serious deficiencies also emerged at this level, particularly regarding implementation and control activities. These deficiencies were aggravated by the fact that vaccines undoubtedly encounter a larger number of potentially damaging contingencies at the local level than they do elsewhere. Suggestions are made for overcoming these difficulties.

The hydrology of three high-altitude forests in Central Himalaya, India: a reconnaissance study

NASA Astrophysics Data System (ADS)

Negi, G. C. S.; Rikhari, H. C.; Garkoti, S. C.

1998-02-01

In this preliminary study the partitioning of rain-water into various components of the hydrological cycle in three high-altitude forests of contrasting tree physiognomies (namely, Aesculus indica, Quercus semecarpifolia and Abies pindrow) were studied in the Nandadevi Biosphere Reserve, Central Himalaya, India. The results are compared with the hydrological characteristics of low-altitude forests of this region. The study has indicated a significant role of tree physiognomy with regard to rainfall partitioning into the various components of the hydrological cycle. It is suggested that A. pindrow (an evergreen tree) should be considered superior to A. indica (a deciduous tree) with regard to soil and water conservation in this region. This work is of relevance to land management programmes pertaining to afforestation, logging and regeneration.

Posterior Wnts Have Distinct Roles in Specification and Patterning of the Planarian Posterior Region

PubMed Central

Sureda-Gómez, Miquel; Pascual-Carreras, Eudald; Adell, Teresa

2015-01-01

The wnt signaling pathway is an intercellular communication mechanism essential in cell-fate specification, tissue patterning and regional-identity specification. A βcatenin-dependent signal specifies the AP (Anteroposterior) axis of planarians, both during regeneration of new tissues and during normal homeostasis. Accordingly, four wnts (posterior wnts) are expressed in a nested manner in central and posterior regions of planarians. We have analyzed the specific role of each posterior wnt and the possible cooperation between them in specifying and patterning planarian central and posterior regions. We show that each posterior wnt exerts a distinct role during re-specification and maintenance of the central and posterior planarian regions, and that the integration of the different wnt signals (βcatenin dependent and independent) underlies the patterning of the AP axis from the central region to the tip of the tail. Based on these findings and data from the literature, we propose a model for patterning the planarian AP axis. PMID:26556349

Posterior Wnts Have Distinct Roles in Specification and Patterning of the Planarian Posterior Region.

PubMed

Sureda-Gómez, Miquel; Pascual-Carreras, Eudald; Adell, Teresa

2015-11-05

The wnt signaling pathway is an intercellular communication mechanism essential in cell-fate specification, tissue patterning and regional-identity specification. A βcatenin-dependent signal specifies the AP (Anteroposterior) axis of planarians, both during regeneration of new tissues and during normal homeostasis. Accordingly, four wnts (posterior wnts) are expressed in a nested manner in central and posterior regions of planarians. We have analyzed the specific role of each posterior wnt and the possible cooperation between them in specifying and patterning planarian central and posterior regions. We show that each posterior wnt exerts a distinct role during re-specification and maintenance of the central and posterior planarian regions, and that the integration of the different wnt signals (βcatenin dependent and independent) underlies the patterning of the AP axis from the central region to the tip of the tail. Based on these findings and data from the literature, we propose a model for patterning the planarian AP axis.

Characteristics and Differences of Lifelong Learning Policy Implementation for the Elderly in Thailand

ERIC Educational Resources Information Center

Dhirathiti, Nopraenue S.; Pichitpatja, Pojjana

2018-01-01

The study examined the process of policy implementation of lifelong learning for the elderly in Thailand, covering four main regions within the country. The study empirically compared inputs, processes, outputs, and outcomes of policy implementation in the north, south, northeast, and central regions of Thailand and captured the rigor of policy…

An Investigation of Elementary Teachers' and Principals' Perceptions of Teacher Working Conditions and Academic Achievement in North Carolina

ERIC Educational Resources Information Center

Applewhite, Michael Anthony

2009-01-01

The purpose of this study was to investigate elementary teachers' and principals' perceptions of working conditions and academic achievement in selected regions in North Carolina public schools. The participants in this study were North Carolina principals and elementary teachers from the north and south central school regions. These educators…

Respect, Recognition and Reconciliation: Emerging Models of Integrated Education in Regions of Conflict

ERIC Educational Resources Information Center

Ben-Nun, Merav

2009-01-01

A comparative case study of integrated schools in two regions of conflict, this study addresses the potential and limitations of education to promote individual and societal processes of change and peace building. In modern societies, education is expected to play a central function in socializing young generations into their culture and the…

Multiscale Simulations Reveal Key Aspects of the Proton Transport Mechanism in the ClC-ec1 Antiporter

PubMed Central

Lee, Sangyun; Swanson, Jessica M.J.; Voth, Gregory A.

2016-01-01

Multiscale reactive molecular dynamics simulations are used to study proton transport through the central region of ClC-ec1, a widely studied ClC transporter that enables the stoichiometric exchange of 2 Cl– ions for 1 proton (H+). It has long been known that both Cl– and proton transport occur through partially congruent pathways, and that their exchange is strictly coupled. However, the nature of this coupling and the mechanism of antiporting remain topics of debate. Here multiscale simulations have been used to characterize proton transport between E203 (Gluin) and E148 (Gluex), the internal and external intermediate proton binding sites, respectively. Free energy profiles are presented, explicitly accounting for the binding of Cl– along the central pathway, the dynamically coupled hydration changes of the central region, and conformational changes of Gluin and Gluex. We find that proton transport between Gluin and Gluex is possible in both the presence and absence of Cl– in the central binding site, although it is facilitated by the anion presence. These results support the notion that the requisite coupling between Cl– and proton transport occurs elsewhere (e.g., during proton uptake or release). In addition, proton transport is explored in the E203K mutant, which maintains proton permeation despite the substitution of a basic residue for Gluin. This collection of calculations provides for the first time, to our knowledge, a detailed picture of the proton transport mechanism in the central region of ClC-ec1 at a molecular level. PMID:27028643

Normal central retinal function and structure preserved in retinitis pigmentosa.

PubMed

Jacobson, Samuel G; Roman, Alejandro J; Aleman, Tomas S; Sumaroka, Alexander; Herrera, Waldo; Windsor, Elizabeth A M; Atkinson, Lori A; Schwartz, Sharon B; Steinberg, Janet D; Cideciyan, Artur V

2010-02-01

To determine whether normal function and structure, as recently found in forms of Usher syndrome, also occur in a population of patients with nonsyndromic retinitis pigmentosa (RP). Patients with simplex, multiplex, or autosomal recessive RP (n = 238; ages 9-82 years) were studied with static chromatic perimetry. A subset was evaluated with optical coherence tomography (OCT). Co-localized visual sensitivity and photoreceptor nuclear layer thickness were measured across the central retina to establish the relationship of function and structure. Comparisons were made to patients with Usher syndrome (n = 83, ages 10-69 years). Cross-sectional psychophysical data identified patients with RP who had normal rod- and cone-mediated function in the central retina. There were two other patterns with greater dysfunction, and longitudinal data confirmed that progression can occur from normal rod and cone function to cone-only central islands. The retinal extent of normal laminar architecture by OCT corresponded to the extent of normal visual function in patients with RP. Central retinal preservation of normal function and structure did not show a relationship with age or retained peripheral function. Usher syndrome results were like those in nonsyndromic RP. Regional disease variation is a well-known finding in RP. Unexpected was the observation that patients with presumed recessive RP can have regions with functionally and structurally normal retina. Such patients will require special consideration in future clinical trials of either focal or systemic treatment. Whether there is a common molecular mechanism shared by forms of RP with normal regions of retina warrants further study.

Kinematics of current region fragmentation in semi-inclusive deeply inelastic scattering

DOE PAGES

Boglione, M.; Collins, J.; Gamberg, L.; ...

2017-01-16

Different kinematical regions of semi-inclusive deeply inelastic scattering (SIDIS) processes correspond to different underlying partonic pictures, and it is important to understand the transition between them. We find criteria in semi-inclusive deeply inelastic scattering (SIDIS) for identifying the current fragmentation region — the kinematical region where a factorization picture with fragmentation functions is appropriate, especially for studies of transverse-momentum-dependent (TMD) functions. This region is distinguished from the central (soft) and target fragmentation regions. The basis of our argument is in the errors in approximations used in deriving factorization. As compared with previous work, we show that it is essential tomore » take account of the transverse momentum of the detected hadron, and we find a much more restricted range for genuine current fragmentation. As a result, we show that it is important to develop an extended factorization formulation to treat hadronization in the central region, as well as the current and target fragmentation regions, and to obtain a unified formalism spanning all rapidities for the detected hadron.« less

Impacts of climate change on forest phenology and implications for streamflow in the central Appalachian Mountains region, United States

NASA Astrophysics Data System (ADS)

Zegre, N.; Gaertner, B. A.; Fernandez, R.

2016-12-01

The timing of phenological parameters such as spring onset and autumn senescence are important controls on the partitioning of water into evaporation and streamflow. Climate largely drives seasonal characteristics of plants and changes in phenological timing can be used to detect the impacts of climate change on water balance controls. However, limited phenological research is available for regions dominated by forest cover such as the central Appalachian Mountains region of the United States. To quantify the impacts of climate change on phenological timing and streamflow in this region, we used GIMMS AVHRR NDVI 13g data from 1982-2012 and the TIMESAT program to extract seasonality parameters. Results show that spring onset has advanced by 9 days, autumn senescence has been delayed by 11 days, and growing season has lengthened by 20 days. Above 500 m elevation, spring onset occurs 2-3 days later; fall senescence arrives 1-2 days earlier, and growing season shortens by 3-5 days. Streamflow has decreased during the growing season over the 31-year study period throughout the region, with the most pronounced effects for the Tennessee River watershed, the southernmost reach of the study area. The elevation patterns are in general agreement with Hopkins law, which states a one-day delay in spring onset for every 30-meter increase in elevation. Streamflow patterns suggest that the southern central Appalachian region is sensitive to changes in climate and are becoming drier, having important implications for drinking water supply, forest ecosystem management, ecosystem services including drinking water supply, and overall forest health.

Neural Mechanisms of Selective Attention in Children with Amblyopia.

PubMed

Zhou, Aibao; Jiang, Yanfei; Chen, Jianming; Wei, Jianlan; Dang, Baobao; Li, Shifeng; Xu, Qiongying

2015-01-01

Previous studies have indicated that amblyopia might affect children's attention. We recruited amblyopic children and normal children aged 9-11 years as study subjects and compared selective attention between the two groups of children. Chinese characters denoting colors were used in the Stroop task, and the event-related potential (ERP) was analyzed. The results show that the accuracy of both groups in the congruent condition was higher than the incongruent condition, and the reaction time (RT) of amblyopic children was longer. The latency of the occipital P1 in the incongruent condition was shorter than the neutral condition for both groups; the peak of the occipital P1 elicited by the incongruent stimuli in amblyopic children was higher. In both groups, the N1 peak was higher in the occipital region than frontal and central regions. The N1 latency of normal children was shorter in the congruent and neutral conditions and longer in the incongruent condition; the N1 peak of normal children was higher. The N270 latencies of normal children in the congruent and neutral conditions were shorter; the N270 peak was higher in parietal and occipital regions than frontal and central regions for both groups. The N450 latency of normal children was shorter; in both groups, the N450 average amplitude was significantly higher in the parietal region than central and frontal regions. The accuracy was the same for both groups, but the response of amblyopic children was significantly slower. The two groups showed differences in both stages of the Stroop task. Normal children showed advantages in processing speed on both stimulus and response conflict stages.Brain regions activated during the Stroop task were consistent between groups, in line with their age characteristics.

Electromagnetic constraints on a melt region beneath the central Mariana back-arc spreading ridge

NASA Astrophysics Data System (ADS)

Matsuno, Tetsuo; Evans, Rob L.; Seama, Nobukazu; Chave, Alan D.

2012-10-01

An electrical resistivity profile across the central Mariana subduction system shows high resistivity in the upper mantle beneath the back-arc spreading ridge where melt might be expected to exist. Although seismic data are equivocal on the extent of a possible melt region, the question arises as to why a 2-D magnetotelluric (MT) survey apparently failed to image any melt. We have run forward models and inversions that test possible 3-D melt geometries that are consistent with the MT data and results of other studies from the region, and that we use to place upper bounds on the possible extent of 3-D melt region beneath the spreading center. Our study suggests that the largest melt region that was not directly imaged by the 2-D MT data, but that is compatible with the observations as well as the likely effects of melt focusing, has a 3-D shape on a ridge-segment scale focused toward the spreading center and a resistivity of 100 Ω-m that corresponds to ˜0.1-˜1% interconnected silicate melt embedded in a background resistivity of ˜500 Ω-m. In contrast to the superfast spreading southern East Pacific Rise, the 3-D melt region suggests that buoyant mantle upwelling on a ridge-segment scale is the dominant process beneath the slow-spreading central Mariana back-arc. A final test considers whether the inability to image a 3-D melt region was a result of the 2-D survey geometry. The result reveals that the 2-D transect completed is useful to elucidate a broad range of 3-D melt bodies.

Does fiscal decentralization improve health outcomes? Evidence from infant mortality in Italy.

PubMed

Cavalieri, Marina; Ferrante, Livio

2016-09-01

Despite financial and decision-making responsibilities having been increasingly devolved to lower levels of government worldwide, the potential impact of these reforms remains largely controversial. This paper investigates the hypothesis that a shift towards a higher degree of fiscal autonomy of sub-national governments could improve health outcomes, as measured by infant mortality rates. Italy is used as a case study since responsibilities for healthcare have been decentralized to regions, though the central government still retains a key role in ensuring all citizens uniform access to health services throughout the country. A linear fixed-effects regression model with robust standard errors is employed for a panel of 20 regions over the period 1996-2012 (340 observations in the full sample). Decentralization is proxied by two different indicators, capturing the degree of decision-making autonomy in the allocation of tax revenues and the extent to which regions rely on fiscal transfers from the central government. The results show that a higher proportion of tax revenues raised and/or controlled locally as well as a lower transfer dependency from the central government are consistently associated with lower infant mortality rates, ceteris paribus. The marginal benefit from fiscal decentralization, however, is not constant but depends on the level of regional wealth, favouring poorest regions. In terms of policy implications, this study outlines how the effectiveness of decentralization in improving health outcomes is contingent on the characteristics of the context in which the process takes place. Copyright © 2016 Elsevier Ltd. All rights reserved.

Geographic distribution of phlebotomine sandfly species (Diptera: Psychodidae) in Central-West Brazil.

PubMed

Almeida, Paulo Silva de; Andrade, Andrey José de; Sciamarelli, Alan; Raizer, Josué; Menegatti, Jaqueline Aparecida; Hermes, Sandra Cristina Negreli Moreira; Carvalho, Maria do Socorro Laurentino de; Gurgel-Gonçalves, Rodrigo

2015-06-01

This study updates the geographic distributions of phlebotomine species in Central-West Brazil and analyses the climatic factors associated with their occurrence. The data were obtained from the entomology services of the state departments of health in Central-West Brazil, scientific collections and a literature review of articles from 1962-2014. Ecological niche models were produced for sandfly species with more than 20 occurrences using the Maxent algorithm and eight climate variables. In all, 2,803 phlebotomine records for 127 species were analysed. Nyssomyia whitmani, Evandromyia lenti and Lutzomyia longipalpis were the species with the greatest number of records and were present in all the biomes in Central-West Brazil. The models, which were produced for 34 species, indicated that the Cerrado areas in the central and western regions of Central-West Brazil were climatically more suitable to sandflies. The variables with the greatest influence on the models were the temperature in the coldest months and the temperature seasonality. The results show that phlebotomine species in Central-West Brazil have different geographical distribution patterns and that climate conditions in essentially the entire region favour the occurrence of at least one Leishmania vector species, highlighting the need to maintain or intensify vector control and surveillance strategies.

Geographic distribution of phlebotomine sandfly species (Diptera: Psychodidae) in Central-West Brazil

PubMed Central

de Almeida, Paulo Silva; de Andrade, Andrey José; Sciamarelli, Alan; Raizer, Josué; Menegatti, Jaqueline Aparecida; Hermes, Sandra Cristina Negreli Moreira; de Carvalho, Maria do Socorro Laurentino; Gurgel-Gonçalves, Rodrigo

2015-01-01

This study updates the geographic distributions of phlebotomine species in Central-West Brazil and analyses the climatic factors associated with their occurrence. The data were obtained from the entomology services of the state departments of health in Central-West Brazil, scientific collections and a literature review of articles from 1962-2014. Ecological niche models were produced for sandfly species with more than 20 occurrences using the Maxent algorithm and eight climate variables. In all, 2,803 phlebotomine records for 127 species were analysed. Nyssomyia whitmani, Evandromyia lenti and Lutzomyia longipalpis were the species with the greatest number of records and were present in all the biomes in Central-West Brazil. The models, which were produced for 34 species, indicated that the Cerrado areas in the central and western regions of Central-West Brazil were climatically more suitable to sandflies. The variables with the greatest influence on the models were the temperature in the coldest months and the temperature seasonality. The results show that phlebotomine species in Central-West Brazil have different geographical distribution patterns and that climate conditions in essentially the entire region favour the occurrence of at least one Leishmania vector species, highlighting the need to maintain or intensify vector control and surveillance strategies. PMID:26018450

Geohydrologic systems in Kansas; physical framework of the confining unit in the Western Interior Plains aquifer system

USGS Publications Warehouse

Hansen, C.V.; Wolf, R.J.; Spinazola, J.M.

1992-01-01

The purpose of this Hydrologic Investigations Atlas is to provide a description of the geohydrologic systems in Upper Cambrian through Lower Cretaceous rocks in Kansas. This investigation was made as part of the Central Midwest Regional Aquifer-System Analysis (CMRASA). The CMRASA is one of several major investigations by the U.S. Geological Survey of regional aquifer systems in the United States. These regional investigations are designed to increase knowledge of the flow regime and hydrologic properties of major aquifer systems and to provide quantitative information for the assessment, development, and management of water supplies. The CMRASA study area includes all or parts of 10 Central Midwestern States (Jorgensen and Signor, 1981), as shown on the envelope cover.

Geohydrologic systems in Kansas physical framework of the western interior plains confining system

USGS Publications Warehouse

Wolf, R.J.; McGovern, Harold E.; Spinazola, Joseph M.

1992-01-01

The purpose of this Hydrologic Investigations Atlas is to provide a description of the principal geohydrologic systems in the Upper Cambrian through Lower Cretaceous rocks in Kansas.  This investigation was made as part of the Central Midwest Regional Aquifer-System Analysis (CMRASA). The CMRASA is one of several major investigations by the U.S. Geological Survey of regional aquifer systems in the United States. These regional investigations are designed to increase knowledge of the flow regime and hydrologic properties of major aquifer systems and to provide quantitative information for assessing, developing, and managing water supplies.  The CMRASA study area includes all or parts of 10 Central Midwestern States (Jorgensen and Signor, 1981) as shown on the envelope cover.

Autotransplantation and Orthodontic Treatment after Maxillary Central Incisor Region Trauma: A 13-Year Follow-Up Case Report Study.

PubMed

Piroozmand, Farzad; Hessari, Hossein; Shirazi, Mohsen; Khazaei, Pegah

2018-01-01

The anterior maxilla is the most prone region to the trauma during childhood, and tooth loss sometimes happens due to trauma. Replacing the missing teeth has always been one of the dentists' challenges in children and adolescents, since their dentofacial growth is not complete. Autotransplantation of mandibular premolars with two-thirds or three-quarters of root formation provides the best prognosis for the tooth survival. This case report describes the management of a 10-year-old boy suffering a severe dental injury who received the autotransplantation of the premolars from mandible to restore the space caused by trauma in maxillary central incisor region and a 13-year follow-up of the autotransplantation.

Holistic Analysis of the Urban Water Systems in Greater Cincinnati Region

EPA Science Inventory

Urban water and wastewater systems with two utilities in Greater Cincinnati region were evaluated as a case study to elucidates a bigger picture of a typical centralized urban water system. Two different integrated assessment metrics were used to analyze the same system. LCA an...

Age-and Brain Region-Specific Differences in Mitochondrial Bioenergetics in Brown Norway Rats

EPA Science Inventory

Mitochondria are central regulators of energy homeostasis and play a pivotal role in mechanisms of cellular senescence. The objective of the present study was to evaluate mitochondrial bio­-energetic parameters in five brain regions [brainstem (BS), frontal cortex (FC), cerebellu...

Artificial Regeneration of Blue and Coast Live Oaks in the Central Coast

Treesearch

Tim R. Plumb; Bennie Hannah

1991-01-01

The primary goal of this study was to find economical and effective planting techniques that will ensure the establishment and early survival of coast live oak (Quercus agrifolia Née) and blue oak (Q. douglasii H. and A.) in the Central Coast region of California. Eight treatments were evaluated ranging from unprotected seed spots...

An Examination of Social Media Policy Usage of South Central United States' Universities

ERIC Educational Resources Information Center

Eaton, Virginia J.; Luse, Donna W.; Hodge, Thomas G.

2012-01-01

Since the use of social media tools by universities has expanded exponentially, a university can easily find itself in a precarious situation in a moment's notice because social media tools have been used inadvertently. This study investigated the social media policies of AACSB-International accredited schools in the SREB South Central Region of…

Campsite impacts in four wildernesses in the south-central United States

Treesearch

Douglas McEwen; David N. Cole; Mark Simon

1996-01-01

Campsite impacts were studied in four wildernesses in the South-Central United States - Caney Creek, AR, Upper Buffalo, AR, Hercules Glades, MO, and Garden of the Gods, IL. Compared with wildernesses in other regions, campsite densities in these wildernesses are low to moderate, while impact intensities on individual campsites are low. Implications for monitoring...

Assessing Cultural Change in North-Central New Mexico.

ERIC Educational Resources Information Center

Eastman, Clyde

A study conducted during the summer of 1969 researched the concept of culture with regard to the acculturation process of Spanish Americans. The Spanish Americans of north-central New Mexico were compared with the Anglo Americans living within that region. Data were collected on 799 adults from the 2 groups by means of personal interviews. Factor…

A comparison of small tractors for thinning central hardwoods

Treesearch

N. Huyler; C.B. LeDoux

1991-01-01

Young-growth hardwood forests in the central hardwood region will require intensive management if they are to help meet the Nation's increasing demand for wood. Such management generally will require entries into the stands when the trees are small. Many small-scale machines are available for harvesting small wood. Time and motion studies were conducted on small-...

Timber resource statistics of south-central Alaska, 2003.

Treesearch

Willem W.S. van Hees

2005-01-01

Estimates of timber resources for south-central Alaska are presented. Data collection began in 2000 and was completed in 2003. All forest lands over all ownerships were considered for sampling. The inventory unit was, roughly, the region between Icy Bay to the east and Kodiak Island to the west. Forest lands within national forest wilderness study areas and recommended...

The Latin-American region and the challenges to develop one homogeneous and harmonized hazard model: preliminary results for the Caribbean and Central America regions in the GEM context

NASA Astrophysics Data System (ADS)

Garcia, J.; Arcila, M.; Benito, B.; Eraso, J.; García, R.; Gomez Capera, A.; Pagani, M.; Pinho, R.; Rendon, H.; Torres, Y.

2013-05-01

Latin America is a seismically active region with complex tectonic settings that make the creation of hazard models challenging. Over the past two decades PSHA studies have been completed for this region in the context of global (Shedlock, 1999), regional (Dimaté et al., 1999) and national initiatives. Currently different research groups are developing new models for various nations. The Global Earthquake Model (GEM), an initiative aiming at the creation of a large global community working collaboratively on building hazard and risk models using open standards and tools, is promoting the collaboration between different national projects and groups so as to facilitate the creation of harmonized regional models. The creation of a harmonized hazard model can follow different approaches, varying from a simple patching of available models to a complete homogenisation of basic information and the subsequent creation of a completely new PSHA model. In this contribution we describe the process and results of a first attempt aiming at the creation of a community based model covering the Caribbean and Central America regions. It consists of five main steps: 1- Identification and collection of available PSHA input models; 2- Analysis of the consistency, transparency and reproducibility of each model; 3- Selection (if more then a model exists for the same region); 4- Representation of the models in a standardized format and incorporation of new knowledge from recent studies; 5- Proposal(s) of harmonization We consider some PHSA studies completed over the latest twenty years in the region comprising the Caribbean (CAR), Central America (CAM) and northern South America (SA), we illustrate a tentative harmonization of the seismic source geometries models and we discuss the steps needed toward a complete harmonisation of the models. Our will is to have a model based on best practices and high standards created though a combination of knowledge and competences coming from the scientific community, incorporating national and regional Institutions. This is an ambitious goal that can be pursued only through an intense and open cooperation between all the interested subjects.

Vortex flows with suspended separation regions and long-range untwisted central jets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abramovich, G.N.; Trofimov, R.S.

1988-05-01

A study is made of possible physicoaerodynamic configurations of vortical flow with suspended separation regions and untwisted central jets. Such flows are encountered in power plants (heat exchangers, combustion chambers, and chemical reactors) and in nature (tornadoes). The basic configurations of several flows of this type are described, including the structure of a flow formed by coaxial cocurrent twisted jets, the flow in a conical swirl chamber with the formation of an untwisted long-range axial jet, the flow pattern in a gas turbine engine chamber, and some considerations regarding the aerodynamics of a tornado.

Epidemiology of Ocular Toxoplasmosis in Three Community Surveys in the Central Region of Ghana, West Africa.

PubMed

Abu, Emmanuel Kwasi; Boampong, Johnson Nyarko; Amoabeng, Joseph Kwame; Ilechie, Alex A; Kyei, Samuel; Owusu-Ansah, Andrew; Boadi-Kusi, Samuel Bert; Amoani, Benjamin; Ayi, Irene

2016-01-01

To conduct the first ever population-based survey on ocular toxoplasmosis in the Central Region of Ghana. A cross-sectional population-based study was conducted in three randomly selected communities in the Central Region, Ghana. Visual acuity (VA) measurement, dilated fundus examination by indirect ophthalmoscopy and serology testing were performed on all participants. Ocular toxoplasmosis was diagnosed based on characteristic retinal lesions and supported by positive serologic testing using commercial enzyme-linked immunosorbent assay (ELISA) kits. A total of 390 subjects aged 10-100 years (mean age 47 years) were examined; 118 (30.3%) were male and 272 (69.7%) female. Ten subjects (6 females and 4 males) had toxoplasmic ocular lesions (prevalence 2.6%). Of these, two had bilateral lesions and eight had unilateral lesions. Subjects with toxoplasmic ocular lesions were older than those without lesions (p = 0.028). The development of ocular toxoplasmosis was not associated with rural dwelling, sex, keeping cats, or consumption of meat. The prevalence of ocular toxoplasmosis in our Ghanaian study population was lower than findings from Southern Brazil, where there is a similar prevalence of infection in the general population.

Mapping lake level changes using ICESat/GLAS satellite laser altimetry data: a case study in arid regions of central Asia

NASA Astrophysics Data System (ADS)

Li, JunLi; Fang, Hui; Yang, Liao

2011-12-01

Lakes in arid regions of Central Asia act as essential components of regional water cycles, providing sparse but valuable water resource for the fragile ecological environments and human lives. Lakes in Central Asia are sensitive to climate change and human activities, and great changes have been found since 1960s. Mapping and monitoring these inland lakes would improve our understanding of mechanism of lake dynamics and climatic impacts. ICESat/GLAS satellite laser altimetry provides an efficient tool of continuously measuring lake levels in these poorly surveyed remote areas. An automated mapping scheme of lake level changes is developed based on GLAS altimetry products, and the spatial and temporal characteristics of 9 typical lakes in Central Asia are analyzed to validate the level accuracies. The results show that ICESat/GLAS has a good performance of lake level monitoring, whose patterns of level changes are the same as those of field observation, and the max differences between GLAS and field data is 3cm. Based on the results, it is obvious that alpine lakes are increasing greatly in lake levels during 2003-2009 due to climate change, while open lakes with dams and plain endorheic lakes decrease dramatically in water levels due to human activities, which reveals the overexploitation of water resource in Central Asia.

Lyman-continuum leakage as dominant source of diffuse ionized gas in the Antennae galaxy

NASA Astrophysics Data System (ADS)

Weilbacher, Peter M.; Monreal-Ibero, Ana; Verhamme, Anne; Sandin, Christer; Steinmetz, Matthias; Kollatschny, Wolfram; Krajnović, Davor; Kamann, Sebastian; Roth, Martin M.; Erroz-Ferrer, Santiago; Marino, Raffaella Anna; Maseda, Michael V.; Wendt, Martin; Bacon, Roland; Dreizler, Stefan; Richard, Johan; Wisotzki, Lutz

2018-04-01

The Antennae galaxy (NGC 4038/39) is the closest major interacting galaxy system and is therefore often studied as a merger prototype. We present the first comprehensive integral field spectroscopic dataset of this system, observed with the MUSE instrument at the ESO VLT. We cover the two regions in this system which exhibit recent star formation: the central galaxy interaction and a region near the tip of the southern tidal tail. In these fields, we detect HII regions and diffuse ionized gas to unprecedented depth. About 15% of the ionized gas was undetected by previous observing campaigns. This newly detected faint ionized gas is visible everywhere around the central merger, and shows filamentary structure. We estimate diffuse gas fractions of about 60% in the central field and 10% in the southern region. We are able to show that the southern region contains a significantly different population of HII regions, showing fainter luminosities. By comparing HII region luminosities with the HST catalog of young star clusters in the central field, we estimate that there is enough Lyman-continuum leakage in the merger to explain the amount of diffuse ionized gas that we detect. We compare the Lyman-continuum escape fraction of each HII region against emission line ratios that are sensitive to the ionization parameter. While we find no systematic trend between these properties, the most extreme line ratios seem to be strong indicators of density bounded ionization. Extrapolating the Lyman-continuum escape fractions to the southern region, we conclude that simply from the comparison of the young stellar populations to the ionized gas there is no need to invoke other ionization mechanisms than Lyman-continuum leaking HII regions for the diffuse ionized gas in the Antennae. FITS images and Table of HII regions are available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A95 and at http://muse-vlt.eu/science/antennae/

NEUTRONIC REACTOR

DOEpatents

Hurwitz, H. Jr.; Brooks, H.; Mannal, C.; Payne, J.H.; Luebke, E.A.

1959-03-24

A reactor of the heterogeneous, liquid cooled type is described. This reactor is comprised of a central region of a plurality of vertically disposed elongated tubes surrounded by a region of moderator material. The central region is comprised of a central core surrounded by a reflector region which is surrounded by a fast neutron absorber region, which in turn is surrounded by a slow neutron absorber region. Liquid sodium is used as the primary coolant and circulates through the core which contains the fuel elements. Control of the reactor is accomplished by varying the ability of the reflector region to reflect neutrons back into the core of the reactor. For this purpose the reflector is comprised of moderator and control elements having varying effects on reactivity, the control elements being arranged and actuated by groups to give regulation, shim, and safety control.

Impacts of biogeographic history and marginal population genetics on species range limits: a case study of Liriodendron chinense.

PubMed

Yang, Aihong; Dick, Christopher W; Yao, Xiaohong; Huang, Hongwen

2016-05-10

Species ranges are influenced by past climate oscillations, geographical constraints, and adaptive potential to colonize novel habitats at range limits. This study used Liriodendron chinense, an important temperate Asian tree species, as a model system to evaluate the roles of biogeographic history and marginal population genetics in determining range limits. We examined the demographic history and genetic diversity of 29 L. chinense populations using both chloroplast and nuclear microsatellite loci. Significant phylogeographic structure was recovered with haplotype clusters coinciding with major mountain regions. Long-term demographical stability was suggested by mismatch distribution analyses, neutrality tests, and ecological niche models (ENM) and suggested the existence of LGM refuges within mountain regions. Differences in genetic diversity between central and marginal populations were not significant for either genomic region. However, asymmetrical gene flow was inferred from central populations to marginal populations, which could potentially limit range adaptation and expansion of L. chinense.

Health conditions and role limitation in three European Regions: a public-health perspective.

PubMed

Barbaglia, Gabriela; Adroher, Núria D; Vilagut, Gemma; Bruffaerts, Ronny; Bunting, Brentan; Caldas de Almeida, José Miguel; Florescu, Silvia; de Girolamo, Giovanni; de Graaf, Ron; Haro, Josep Maria; Hinkov, Hristo; Kovess-Masfety, Vivianne; Matschinger, Herbert; Alonso, Jordi

To describe the distribution of role limitation in the European population aged 18-64 years and to examine the contribution of health conditions to role limitation using a public-health approach. Representative samples of the adult general population (n=13,666) aged 18-64 years from 10 European countries of the World Mental Health (WMH) Surveys Initiative, grouped into three regions: Central-Western, Southern and Central-Eastern. The Composite International Diagnostic Interview (CIDI 3.0) was used to assess six mental disorders and standard checklists for seven physical conditions. Days with full and with partial role limitation in the month previous to the interview were reported (WMH-WHODAS). Population Attributable Fraction (PAFs) of full and partial role limitation were estimated. Health conditions explained a large proportion of full role limitation (PAF=62.6%) and somewhat less of partial role limitation (46.6%). Chronic pain was the single condition that consistently contributed to explain both disability measures in all European Regions. Mental disorders were the most important contributors to full and partial role limitation in Central-Western and Southern Europe. In Central-Eastern Europe, where mental disorders were less prevalent, physical conditions, especially cardiovascular diseases, were the highest contributors to disability. The contribution of health conditions to role limitation in the three European regions studied is high. Mental disorders are associated with the largest impact in most of the regions. There is a need for mainstreaming disability in the public health agenda to reduce the role limitation associated with health conditions. The cross-regional differences found require further investigation. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

Climatology and trends of summer high temperature days in India during 1969-2013

NASA Astrophysics Data System (ADS)

Jaswal, A. K.; Rao, P. C. S.; Singh, Virendra

2015-02-01

Based on the daily maximum air temperature data from 176 stations in India from 1969 to 2013, the climatological distribution of the number of days with high temperature (HT) defined as days with maximum temperature higher than 37°C during summer season (March-June) are studied. With a focus on the regional variability and long-term trends, the impacts of HT days are examined by dividing the country into six geographical regions (North, West, North-central, East, South-central and South). Although the long-term (1969-2013) climatological numbers of HT days display well-defined spatial patterns, there is clear change in climatological mean and coefficient of variation of HT days in a recent period (1991-2013). The long period trends indicate increase in summer HT days by 3%, 5%, and 18% in north, west, and south regions, respectively and decrease by 4% and 9% in north-central and east regions respectively. However, spatial variations in HT days exist across different regions in the country. The data analysis shows that 2010 was the warmest summer year and 2013 was the coolest summer year in India. Comparison of spatial distributions of trends in HT days for 1969-1990 and 1991-2013 periods reveal that there is an abrupt increase in the number of HT days over north, west and north-central regions of India probably from mid 1990s. A steep increase in summer HT days in highly populated cities of Mumbai, New Delhi, Chennai, Jaipur, and Visakhapatnam is noticed during the recent period of 1991-2013. The summer HT days over southern India indicate significant positive correlation with Nino 3.4 index for three months' running mean (December-January-February, January-March, February-April, March-May and April-June).

Hydroclimatic variability in loess δDwax records from the central Chinese Loess Plateau over the past 250 ka

NASA Astrophysics Data System (ADS)

Wang, Zheng; An, Zhisheng; Liu, Zhonghui; Qiang, Xiaoke; Zhang, Fan; Liu, Weiguo

2018-04-01

This study reports hydrogen isotopic records from the central Chinese Loess Plateau (CLP) over the past 250 ka. After eliminating the influence of ice and local temperatures, the δDwax records extracted from two loess sites at Xifeng and Luochuan can be taken to represent arid/humid alternations in the hydrological environment in this marginal Asian Summer Monsoon (ASM) region; they also contain integrated information on summer precipitation patterns and the corresponding responses to these changes by predominant vegetation cover types. These arid/humid alternations show 100 ka, 40 ka and 20 ka cycles. An increase in precipitation in association with an enhanced summer monsoon has historically been taken to be the major factor driving a humid environment in the central CLP. However, hydroclimatic changes in δDwax records differ for the central CLP, central China and southern China. Over a 20 ka cycle, the influence of solar insolation on hydroclimatic changes can be shown to be consistent throughout the central CLP. However, changes in the relative location of the land and sea may have caused different hydroclimatic responses between southern China and the central CLP on a glacial-interglacial scale. The hydroclimatic variability in the central CLP would suggest that an enhanced summer monsoon due to climatic warming is the key to understanding decreased drought degree in this marginal monsoonal region.

Rapidities of produced particles in 200-GeV/ c. pi. sup + /p/K sup + interactions on Au, Ag, and Mg

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brick, D.H.; Widgoff, M.; Beilliere, P.

1990-02-01

We have used the Fermilab 30-in. bubble chamber--hybrid spectrometer to study the rapidities of produced particles'' in the interactions of 200-GeV/{ital c} protons and {pi}{sup +} and {ital K}{sup +} mesons with nuclei of gold, silver, and magnesium. The average rapidity decreases linearly with the number of projectile collisions {nu}{sub {ital p}} (up to {nu}{sub {ital p}}=5) with no {ital A} dependence and little beam dependence. The ratio {ital R} of normalized rapidity distributions for hadron-nucleus to hadron-proton interactions shows a plateau in the central region, and becomes much larger in the target region. However, the increase is significantly lessmore » than has been reported in previous experiments. As a function of {nu}{sub {ital p}}, the ratio {ital R} rises linearly in the target region, more gently in the central region, and decreases slowly in the projectile region, in all cases with no {ital A} dependence. Some discrepancies with a previous experiment are observed in the central region. Long-range rapidity correlations are observed in hadron-nucleus events, but not in hadron-proton events. For the former, it is shown that the correlations exist only for those events with multiple projectile collisions, as expected in the multichain dual parton model.« less

Transcriptomic Profiling of Central Nervous System Regions in Three Species of Honey Bee during Dance Communication Behavior

PubMed Central

Sen Sarma, Moushumi; Rodriguez-Zas, Sandra L.; Hong, Feng; Zhong, Sheng; Robinson, Gene E.

2009-01-01

Background We conducted a large-scale transcriptomic profiling of selected regions of the central nervous system (CNS) across three species of honey bees, in foragers that were performing dance behavior to communicate to their nestmates the location, direction and profitability of an attractive floral resource. We used microarrays to measure gene expression in bees from Apis mellifera, dorsata and florea, species that share major traits unique to the genus and also show striking differences in biology and dance communication. The goals of this study were to determine the extent of regional specialization in gene expression and to explore the molecular basis of dance communication. Principal Findings This “snapshot” of the honey bee CNS during dance behavior provides strong evidence for both species-consistent and species-specific differences in gene expression. Gene expression profiles in the mushroom bodies consistently showed the biggest differences relative to the other CNS regions. There were strong similarities in gene expression between the central brain and the second thoracic ganglion across all three species; many of the genes were related to metabolism and energy production. We also obtained gene expression differences between CNS regions that varied by species: A. mellifera differed the most, while dorsata and florea tended to be more similar. Significance Species differences in gene expression perhaps mirror known differences in nesting habit, ecology and dance behavior between mellifera, florea and dorsata. Species-specific differences in gene expression in selected CNS regions that relate to synaptic activity and motor control provide particularly attractive candidate genes to explain the differences in dance behavior exhibited by these three honey bee species. Similarities between central brain and thoracic ganglion provide a unique perspective on the potential coupling of these two motor-related regions during dance behavior and perhaps provide a snapshot of the energy intensive process of dance output generation. Mushroom body results reflect known roles for this region in the regulation of learning, memory and rhythmic behavior. PMID:19641619

Transcriptomic profiling of central nervous system regions in three species of honey bee during dance communication behavior.

PubMed

Sen Sarma, Moushumi; Rodriguez-Zas, Sandra L; Hong, Feng; Zhong, Sheng; Robinson, Gene E

2009-07-29

We conducted a large-scale transcriptomic profiling of selected regions of the central nervous system (CNS) across three species of honey bees, in foragers that were performing dance behavior to communicate to their nestmates the location, direction and profitability of an attractive floral resource. We used microarrays to measure gene expression in bees from Apis mellifera, dorsata and florea, species that share major traits unique to the genus and also show striking differences in biology and dance communication. The goals of this study were to determine the extent of regional specialization in gene expression and to explore the molecular basis of dance communication. This "snapshot" of the honey bee CNS during dance behavior provides strong evidence for both species-consistent and species-specific differences in gene expression. Gene expression profiles in the mushroom bodies consistently showed the biggest differences relative to the other CNS regions. There were strong similarities in gene expression between the central brain and the second thoracic ganglion across all three species; many of the genes were related to metabolism and energy production. We also obtained gene expression differences between CNS regions that varied by species: A. mellifera differed the most, while dorsata and florea tended to be more similar. Species differences in gene expression perhaps mirror known differences in nesting habit, ecology and dance behavior between mellifera, florea and dorsata. Species-specific differences in gene expression in selected CNS regions that relate to synaptic activity and motor control provide particularly attractive candidate genes to explain the differences in dance behavior exhibited by these three honey bee species. Similarities between central brain and thoracic ganglion provide a unique perspective on the potential coupling of these two motor-related regions during dance behavior and perhaps provide a snapshot of the energy intensive process of dance output generation. Mushroom body results reflect known roles for this region in the regulation of learning, memory and rhythmic behavior.

Large-scale cortical volume correlation networks reveal disrupted small world patterns in Parkinson's disease.

PubMed

Wu, Qiong; Gao, Yang; Liu, Ai-Shi; Xie, Li-Zhi; Qian, Long; Yang, Xiao-Guang

2018-01-01

To date, the most frequently reported neuroimaging biomarkers in Parkinson's disease (PD) are direct brain imaging measurements focusing on local disrupted regions. However, the notion that PD is related to abnormal functional and structural connectivity has received support in the past few years. Here, we employed graph theory to analyze the structural co-variance networks derived from 50 PD patients and 48 normal controls (NC). Then, the small world properties of brain networks were assessed in the structural networks that were constructed based on cortical volume data. Our results showed that both the PD and NC groups had a small world architecture in brain structural networks. However, the PD patients had a higher characteristic path length and clustering coefficients compared with the NC group. With regard to the nodal centrality, 11 regions, including 3 association cortices, 5 paralimbic cortices, and 3 subcortical regions were identified as hubs in the PD group. In contrast, 10 regions, including 7 association cortical regions, 2 paralimbic cortical regions, and the primary motor cortex region, were identified as hubs. Moreover, the regional centrality was profoundly affected in PD patients, including decreased nodal centrality in the right inferior occipital gyrus and the middle temporal gyrus and increased nodal centrality in the right amygdala, the left caudate and the superior temporal gyrus. In addition, the structural cortical network of PD showed reduced topological stability for targeted attacks. Together, this study shows that the coordinated patterns of cortical volume network are widely altered in PD patients with a decrease in the efficiency of parallel information processing. These changes provide structural evidence to support the concept that the core pathophysiology of PD is associated with disruptive alterations in the coordination of large-scale brain networks that underlie high-level cognition. Copyright © 2017. Published by Elsevier B.V.

A review of bioinformatics training applied to research in molecular medicine, agriculture and biodiversity in Costa Rica and Central America.

PubMed

Orozco, Allan; Morera, Jessica; Jiménez, Sergio; Boza, Ricardo

2013-09-01

Today, Bioinformatics has become a scientific discipline with great relevance for the Molecular Biosciences and for the Omics sciences in general. Although developed countries have progressed with large strides in Bioinformatics education and research, in other regions, such as Central America, the advances have occurred in a gradual way and with little support from the Academia, either at the undergraduate or graduate level. To address this problem, the University of Costa Rica's Medical School, a regional leader in Bioinformatics in Central America, has been conducting a series of Bioinformatics workshops, seminars and courses, leading to the creation of the region's first Bioinformatics Master's Degree. The recent creation of the Central American Bioinformatics Network (BioCANET), associated to the deployment of a supporting computational infrastructure (HPC Cluster) devoted to provide computing support for Molecular Biology in the region, is providing a foundational stone for the development of Bioinformatics in the area. Central American bioinformaticians have participated in the creation of as well as co-founded the Iberoamerican Bioinformatics Society (SOIBIO). In this article, we review the most recent activities in education and research in Bioinformatics from several regional institutions. These activities have resulted in further advances for Molecular Medicine, Agriculture and Biodiversity research in Costa Rica and the rest of the Central American countries. Finally, we provide summary information on the first Central America Bioinformatics International Congress, as well as the creation of the first Bioinformatics company (Indromics Bioinformatics), spin-off the Academy in Central America and the Caribbean.

Evolution of the Earthquake Catalog in Central America

NASA Astrophysics Data System (ADS)

Rojas, W.; Camacho, E. I.; Marroquín, G.; Molina, E.; Talavera, E.; Benito, M. B.; Lindholm, C.

2013-05-01

Central America (CA) is known as a seismically active region in which several historic destructive earthquakes have occurred. This fact has promoved the development of seismic hazard studies that provide necessary estimates for decision making and risk assessment efforts, requiring a complete and standardized seismic catalog. With this aim, several authors have contributed to the study of the historical seismicity of Central America (e.g. Grases, Feldaman; White y Harlow, 1993; White et al. 2004; Ambraseys y Adams, 2001; Peraldo y Montero, 1999), who complied historical data. A first catalogue was developed by Rojas (1993) that comprises the 1522 to 1993 period. This information was integrated in 2007, together with data from the International Seismological Centre (CASC) and the national catalogs of CA countries in a new regional catalogue. Since 2007 a continuous effort has been done in order to complete and update this CA earthquake catalog. In particular, two workshops were held in 2008 and 2011 in the Universidad Politécnica de Madrid (Spain), joining experts from the different CA countries who worked each one in its own catalogue covering the entire region and the border with northwestern Colombia and southern Mexico. These national catalogues were later integrated in a common regional catalogue in SEISAN format. At this aim it was necessary to solve some problems, like to avoid duplicity of events, specially close to the boundaries, to consider the different scales of magnitude adopted by different countries, to take into account the completeness by the different national networks, etc. Some solutions were adopted for obtaining a homogenized catalogue to Mw, containing historical and instrumental events with Mw > 3.5 from 1522 up to 2011. The catalogue updated to December 2007 was the basis for the first regional hazard study carried out by Benito et al., (2011) as part of the collaborative RESIS II project under coordination of NORSAR. The ones updated to 2011 is been used in a new seismic hazard study for the entire region. The responsable institutions of each CA country are: INSIVUMEH in Guatemala; Servicio Nacional de Estudios Territoriales, (SNET) in El Salvador; Red Sismológica National-RSN and Observatorio Sismológico and Vulcanológico de Costa Rica-OVSICORI, Observatorio Sismológico de la Universidad de Panama-UPA and Centro Sismológico de America Central, CASC This catalog is a very useful tool to conduct regional or local seismic hazard studies.

Elasto-plastic deformation and plate weakening due to normal faulting in the subducting plate along the Mariana Trench

NASA Astrophysics Data System (ADS)

Zhou, Zhiyuan; Lin, Jian

2018-06-01

We investigated variations in the elasto-plastic deformation of the subducting plate along the Mariana Trench through an analysis of flexural bending and normal fault characteristics together with geodynamic modeling. Most normal faults were initiated at the outer-rise region and grew toward the trench axis with strikes mostly subparallel to the local trench axis. The average trench relief and maximum fault throws were measured to be significantly greater in the southern region (5 km and 320 m, respectively) than the northern and central regions (2 km and 200 m). The subducting plate was modeled as an elasto-plastic slab subjected to tectonic loading at the trench axis. The calculated strain rates and velocities revealed an array of normal fault-like shear zones in the upper plate, resulting in significant faulting-induced reduction in the deviatoric stresses. We then inverted for solutions that best fit the observed flexural bending and normal faulting characteristics, revealing normal fault penetration to depths of 21, 20, and 32 km beneath the seafloor for the northern, central, and southern regions, respectively, which is consistent with the observed depths of the relocated normal faulting earthquakes in the central Mariana Trench. The calculated deeper normal faults of the southern region might lead to about twice as much water being carried into the mantle per unit trench length than the northern and central regions. We further calculated that normal faulting has reduced the effective elastic plate thickness Te by up to 52% locally in the southern region and 33% in both the northern and central regions. The best-fitting solutions revealed a greater apparent angle of the pulling force in the southern region (51-64°) than in the northern (22-35°) and central (20-34°) regions, which correlates with a general southward increase in the seismically-determined dip angle of the subducting slab along the Mariana Trench.

Evaluating regional differences in macroinvertebrate communities from forested depressional wetlands across eastern and central North America

Treesearch

Darold P. Batzer; Susan E. Dietz-Brantley; Barbara E. Taylor; Adrienne E. DeBiase

2005-01-01

Forested depressional wetlands are an important seasonal wetland type across eastern and central North America. Macroinvertebrates are crucial ecosystem components of most forested depressional wetlands, but community compositions can vary widely across the region. We evaluated variation in macroinvertebrate faunas across eastern and central North America using 5...

Connecting Students, Creating Futures at Central Campus

ERIC Educational Resources Information Center

Rosin, Julie; Erbes, Elizabeth; Britt, James; Good, Bill

2012-01-01

Des Moines is an urban community located in the heart of Iowa. Des Moines Public Schools serves 32,000 students in a system with 62 buildings, including Central Campus--a Regional Academy. Central Campus is housed in four buildings, including the main campus at 1800 Grand located on the western edge of downtown Des Moines. As a regional academy,…

9 CFR 93.422 - Import permit and declaration for ruminants.

Code of Federal Regulations, 2010 CFR

2010-01-01

... regions of Central America or of the West Indies, the importer shall first apply for and obtain from APHIS...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Ruminants Central America and West Indies 9 § 93... paragraph (c) of § 93.423. 9 Importations from regions of Central America and the West Indies shall be...

Aberrant Global and Regional Topological Organization of the Fractional Anisotropy-weighted Brain Structural Networks in Major Depressive Disorder

PubMed Central

Chen, Jian-Huai; Yao, Zhi-Jian; Qin, Jiao-Long; Yan, Rui; Hua, Ling-Ling; Lu, Qing

2016-01-01

Background: Most previous neuroimaging studies have focused on the structural and functional abnormalities of local brain regions in major depressive disorder (MDD). Moreover, the exactly topological organization of networks underlying MDD remains unclear. This study examined the aberrant global and regional topological patterns of the brain white matter networks in MDD patients. Methods: The diffusion tensor imaging data were obtained from 27 patients with MDD and 40 healthy controls. The brain fractional anisotropy-weighted structural networks were constructed, and the global network and regional nodal metrics of the networks were explored by the complex network theory. Results: Compared with the healthy controls, the brain structural network of MDD patients showed an intact small-world topology, but significantly abnormal global network topological organization and regional nodal characteristic of the network in MDD were found. Our findings also indicated that the brain structural networks in MDD patients become a less strongly integrated network with a reduced central role of some key brain regions. Conclusions: All these resulted in a less optimal topological organization of networks underlying MDD patients, including an impaired capability of local information processing, reduced centrality of some brain regions and limited capacity to integrate information across different regions. Thus, these global network and regional node-level aberrations might contribute to understanding the pathogenesis of MDD from the view of the brain network. PMID:26960371

Molecular evolution of respiratory syncytial virus subgroup A genotype NA1 and ON1 attachment glycoprotein (G) gene in central Vietnam.

PubMed

Yoshihara, Keisuke; Le, Minh Nhat; Nagasawa, Koo; Tsukagoshi, Hiroyuki; Nguyen, Hien Anh; Toizumi, Michiko; Moriuchi, Hiroyuki; Hashizume, Masahiro; Ariyoshi, Koya; Dang, Duc Anh; Kimura, Hirokazu; Yoshida, Lay-Myint

2016-11-01

We performed molecular evolutionary analyses of the G gene C-terminal 3rd hypervariable region of RSV-A genotypes NA1 and ON1 strains from the paediatric acute respiratory infection patients in central Vietnam during the 2010-2012 study period. Time-scaled phylogenetic analyses were performed using Bayesian Markov Chain Monte Carlo (MCMC) method, and pairwise distances (p-distances) were calculated. Bayesian Skyline Plot (BSP) was constructed to analyze the time-trend relative genetic diversity of central Vietnam RSV-A strains. We also estimated the N-glycosylation sites within G gene hypervariable region. Amino acid substitutions under positive and negative selection pressure were examined using Conservative Single Likelihood Ancestor Counting (SLAC), Fixed Effects Likelihood (FEL), Internal Fixed Effects Likelihood (IFEL) and Mixed Effects Model for Episodic Diversifying Selection (MEME) models. The majority of central Vietnam ON1 strains detected in 2012 were classified into lineage 1 with few positively selected substitutions. As for the Vietnamese NA1 strains, four lineages were circulating during the study period with a few positive selection sites. Shifting patterns of the predominantly circulating NA1 lineage were observed in each year during the investigation period. Median p-distance of central Vietnam NA1 strains was wider (p-distance=0.028) than that of ON1 (p-distance=0.012). The molecular evolutionary rate of central Vietnam ON1 strains was estimated to be 2.55×10 -2 (substitutions/site/year) and was faster than NA1 (7.12×10 -3 (substitutions/site/year)). Interestingly, the evolutionary rates of both genotypes ON1 and NA1 strains from central Vietnam were faster than the global strains respectively. Furthermore, the shifts of N-glycosylation pattern within the G gene 3rd hypervariable region of Vietnamese NA1 strains were observed in each year. BSP analysis indicated the rapid growth of RSV-A effective population size in early 2012. These results suggested that the molecular evolution of RSV-A G gene detected in central Vietnam was fast with unique evolutionary dynamics. Copyright © 2016 Elsevier B.V. All rights reserved.

Assessing the performance of centralized waiting lists for patients without a regular family physician using clinical-administrative data.

PubMed

Breton, Mylaine; Smithman, Mélanie Ann; Brousselle, Astrid; Loignon, Christine; Touati, Nassera; Dubois, Carl-Ardy; Nour, Kareen; Boivin, Antoine; Berbiche, Djamal; Roberge, Danièle

2017-01-05

With 4.6 million patients who do not have a regular family physician, Canada performs poorly compared to other OECD countries in terms of attachment to a family physician. To address this issue, several provinces have implemented centralized waiting lists to coordinate supply and demand for attachment to a family physician. Although significant resources are invested in these centralized waiting lists, no studies have measured their performance. In this article, we present a performance assessment of centralized waiting lists for unattached patients implemented in Quebec, Canada. We based our approach on the Balanced Scorecard method. A committee of decision-makers, managers, healthcare professionals, and researchers selected five indicators for the performance assessment of centralized waiting lists, including both process and outcome indicators. We analyzed and compared clinical-administrative data from 86 centralized waiting lists (GACOs) located in 14 regions in Quebec, from April 1, 2013, to March 31, 2014. During the study period, although over 150,000 patients were attached to a family physician, new requests resulted in a 30% median increase in patients on waiting lists. An inverse correlation of average strength was found between the rates of patients attached to a family physician and the proportion of vulnerable patients attached to a family physician meaning that as more patients became attached to an FP through GACOs, the proportion of vulnerable patients became smaller (r = -0.31, p < 0.005). The results showed very large performance variations both among GACOs of different regions and among those of a same region for all performance indicators. Centralized waiting lists for unattached patients in Quebec seem to be achieving their twofold objective of attaching patients to a family physician and giving priority to vulnerable patients. However, the demand for attachment seems to exceed the supply and there appears to be a tension between giving priority to vulnerable patients and attaching of a large number of patients. Results also showed heterogeneity in the performance of centralized waiting lists across Quebec. Finally, our findings suggest it is critical that similar mechanisms should use available data to identify the best strategies for reducing variations and improving performance.

Using data from a multi-hospital clinical network to explore prevalence of pediatric rickets in Kenya

PubMed Central

Karuri, Stella W.; Murithi, Maureen K.; Irimu, Grace; English, Mike

2017-01-01

Background: Nutritional rickets is a public health concern in developing countries despite tropical climates and a re-emerging issue in developed countries. In this study, we reviewed pediatric admission data from the Clinical Information Network (CIN) to help determine hospital and region based prevalence of rickets in three regions of Kenya (Central Kenya, Western Kenya and Nairobi County). We also examine the association of rickets with other diagnosis, such as malnutrition and pneumonia, and study the effect of rickets on regional hospital stays. Methods: We analyzed discharge records for children aged 1 month to 5 years from county (formerly district) hospitals in the CIN, with admissions from February 1 st 2014 to February 28 th 2015. The strength of the association between rickets and key demographic factors, as well as with malnutrition and pneumonia, was assessed using odds ratios. The Fisher exact test was used to test the significance of the estimated odd ratios. Kaplan-Meier curves were used to analyze length of hospital stays. Results: There was a marked difference in prevalence across the three regions, with Nairobi having the highest number of cases of rickets at a proportion of 4.01%, followed by Central Region at 0.92%. Out of 9756 admissions in the Western Region, there was only one diagnosis of rickets. Malnutrition was associated with rickets; this association varied regionally. Pneumonia was found to be associated with rickets in Central Kenya. Children diagnosed with rickets had longer hospital stays, even when cases of malnutrition and pneumonia were excluded in the analysis. Conclusion: There was marked regional variation in hospital based prevalence of rickets, but in some regions it is a common clinical diagnosis suggesting the need for targeted public health interventions. Factors such as maternal and child nutrition, urbanization and cultural practices might explain these differences. PMID:29062911

Structural covariance and cortical reorganisation in schizophrenia: a MRI-based morphometric study.

PubMed

Palaniyappan, Lena; Hodgson, Olha; Balain, Vijender; Iwabuchi, Sarina; Gowland, Penny; Liddle, Peter

2018-05-06

In patients with schizophrenia, distributed abnormalities are observed in grey matter volume. A recent hypothesis posits that these distributed changes are indicative of a plastic reorganisation process occurring in response to a functional defect in neuronal information transmission. We investigated the structural covariance across various brain regions in early-stage schizophrenia to determine if indeed the observed patterns of volumetric loss conform to a coordinated pattern of structural reorganisation. Structural magnetic resonance imaging scans were obtained from 40 healthy adults and 41 age, gender and parental socioeconomic status matched patients with schizophrenia. Volumes of grey matter tissue were estimated at the regional level across 90 atlas-based parcellations. Group-level structural covariance was studied using a graph theoretical framework. Patients had distributed reduction in grey matter volume, with high degree of localised covariance (clustering) compared with controls. Patients with schizophrenia had reduced centrality of anterior cingulate and insula but increased centrality of the fusiform cortex, compared with controls. Simulating targeted removal of highly central nodes resulted in significant loss of the overall covariance patterns in patients compared with controls. Regional volumetric deficits in schizophrenia are not a result of random, mutually independent processes. Our observations support the occurrence of a spatially interconnected reorganisation with the systematic de-escalation of conventional 'hub' regions. This raises the question of whether the morphological architecture in schizophrenia is primed for compensatory functions, albeit with a high risk of inefficiency.

Carbon stock and its responses to climate change in Central Asia.

PubMed

Li, Chaofan; Zhang, Chi; Luo, Geping; Chen, Xi; Maisupova, Bagila; Madaminov, Abdullo A; Han, Qifei; Djenbaev, Bekmamat M

2015-05-01

Central Asia has a land area of 5.6 × 10(6) km(2) and contains 80-90% of the world's temperate deserts. Yet it is one of the least characterized areas in the estimation of the global carbon (C) stock/balance. This study assessed the sizes and spatiotemporal patterns of C pools in Central Asia using both inventory (based on 353 biomass and 284 soil samples) and process-based modeling approaches. The results showed that the C stock in Central Asia was 31.34-34.16 Pg in the top 1-m soil with another 10.42-11.43 Pg stored in deep soil (1-3 m) of the temperate deserts. They amounted to 18-24% of the global C stock in deserts and dry shrublands. The C stock was comparable to that of the neighboring regions in Eurasia or major drylands around the world (e.g. Australia). However, 90% of Central Asia C pool was stored in soil, and the fraction was much higher than in other regions. Compared to hot deserts of the world, the temperate deserts in Central Asia had relatively high soil organic carbon density. The C stock in Central Asia is under threat from dramatic climate change. During a decadal drought between 1998 and 2008, which was possibly related to protracted La Niña episodes, the dryland lost approximately 0.46 Pg C from 1979 to 2011. The largest C losses were found in northern Kazakhstan, where annual precipitation declined at a rate of 90 mm decade(-1) . The regional C dynamics were mainly determined by changes in the vegetation C pool, and the SOC pool was stable due to the balance between reduced plant-derived C influx and inhibited respiration. © 2015 John Wiley & Sons Ltd.

Using LiDAR and remote microclimate loggers to downscale near-surface air temperatures for site-level studies

Treesearch

Andrew D. George; Frank R. Thompson; John. Faaborg

2015-01-01

A spatial mismatch exists between regional climate models and conditions experienced by individual organisms. We demonstrate an approach to downscaling air temperatures for site-level studies using airborne LiDAR data and remote microclimate loggers. In 2012-2013, we established a temperature logger network in the forested region of central Missouri, USA, and obtained...

Functional Assessment of Alaska Peatlands in Cook Inlet Basin, Region 10 Regional Applied Research Effort (RARE)

EPA Science Inventory

Peatlands in south central Alaska are the dominant wetland class in the lowlands of the Cook Inlet Basin. Currently Alaska peatlands are extensive and largely pristine but these areas are facing increasing human development. This study focused on obtaining measures of ecologica...

The Role of Multicultural Personality in Predicting University Adjustment of International Students in Turkey

ERIC Educational Resources Information Center

Kagnici, Dilek Yelda

2012-01-01

The study examined how particular demographic and multicultural personality variables might predict university adjustment of international students in Turkey. One hundred and twenty-one international students from five geographical regions, including Middle Central Asia, the Balkans, the Middle East, the Kafkasia Region, and the Russian…

A comparative study of texture and rheology of Argentinian honeys from two regions.

PubMed

Maldonado, Ezequiel; Navarro, Alba S; Yamul, Diego K

2018-06-23

The rheological and textural properties of 26 eastern Argentinian honeys from two different regions (North and Central) were investigated. The viscosity curves of the samples were obtained using a rotational rheometer over a temperature range of 10 to 50°C. The viscosity decreased with temperature and all honeys showed a Newtonian behaviour. The temperature dependence of viscosity was described using the Arrhenius, Williams- Landel-Ferry, Vogel-Taumman-Fulcher and Power Law models. The glass transition temperatures of honeys were measured with differential scanning calorimetry and values ranged from -42.63 to -47.71°C. The glass transition temperature was also predicted with the Williams- Landel-Ferry model and no significant differences were observed with the experimental results. Rheological parameters were obtained by small amplitude oscillation experiments. Results indicated that the viscous modulus was higher than the storage modulus within all the frequency ranges assayed and honeys from the North region were more viscous. Results of the back extrusion test showed that honeys from the Central region are harder and both groups of honeys (North and Central) exhibited the same consistency and adhesivity. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Influence of ENSO on Gulf Stream cyclogenesis and the North Atlantic storm track

NASA Astrophysics Data System (ADS)

Li, C.; Schemm, S.; Ciasto, L.; Kvamsto, N. G.

2015-12-01

There is emerging evidence that climate in the North Atlantic-European sector is sensitive to vacillations of tropical Pacific sea surface temperatures, in particular, the central Pacific flavour of the El Nino Southern Oscillation (ENSO) and concomitant trends in atmospheric heating. The frequency of central Pacific ENSOs appears to have increased over the last decades and some studies suggest it may continue increasing in the future, but the precise mechanisms by which these events affect the North Atlantic synoptic scale circulation are poorly understood. Here, we show that central Pacific ENSOs influence where midlatitude cyclogenesis occurs over the Gulf Stream, producing more cyclogenesis in the jet exit region rather than in the climatologically preferred jet entrance region. The cyclones forming over the Gulf Stream in central Pacific ENSO seasons tend to veer north, penetrating deeper into the Arctic rather than into continental Europe. The shift in cyclogenesis is linked to changes in the large scale circulation, namely, the upper-level trough formed in the lee of the Rocky Mountains.

Suppression of Rayleigh backscattering noise using cascaded-SOA and microwave photonic filter for 10 Gb/s loop-back WDM-PON.

PubMed

Feng, Hanlin; Ge, Jia; Xiao, Shilin; Fok, Mable P

2014-05-19

In this paper, we present a novel Rayleigh backscattering (RB) noise mitigation scheme based on central carrier suppression for 10 Gb/s loop-back wavelength division multiplexing passive optical network (WDM-PON). Microwave modulated multi-subcarrier optical signal is used as downstream seeding light, while cascaded semiconductor optical amplifier (SOA) are used in the optical network unit (ONU) for suppressing the central carrier of the multi-subcarrier upstream signal. With central carrier suppression, interference generated by carrier RB noise at low frequency region is eliminated successfully. Transmission performance over 45 km single mode fiber (SMF) is studied experimentally, and the optical-signal-to-Rayleigh-noise-ratio (OSRNR) can be reduced to 15 dB with central carrier suppression ratio (CCSR) of 21 dB. Receiver sensitivity is further improved by 6 dB with the use of microwave photonic filter (MPF) for suppressing residual upstream microwave signal and residual carrier RB at high frequency region.

Effect of the hardwood resource on the sawmill industry in the central and Appalachian regions

Treesearch

William Luppold

1995-01-01

The Central and Appalachian hardwood regions contain a diverse and valuable timber resource. The regions are important to the hardwood industry because they contain 68 percent of the eastern hardwood sawtimber. Furthermore, more than 70 percent of the hardwood lumber produced in the United States is manufactured at mills located in 16 of the states in the regions. This...

Basement Structure and Styles of Active Tectonic Deformation in Central Interior Alaska

NASA Astrophysics Data System (ADS)

Dixit, N.; Hanks, C.

2017-12-01

Central Interior Alaska is one of the most seismically active regions in North America, exhibiting a high concentration of intraplate earthquakes approximately 700 km away from the southern Alaska subduction zone. Based on increasing seismological evidence, intraplate seismicity in the region does not appear to be uniformly distributed, but concentrated in several discrete seismic zones, including the Nenana basin and the adjacent Tanana basin. Recent seismological and neotectonics data further suggests that these seismic zones operate within a field of predominantly pure shear driven primarily by north-south crustal shortening. Although the location and magnitude of the seismic activity in both basins are well defined by a network of seismic stations in the region, the tectonic controls on intraplate earthquakes and the heterogeneous nature of Alaska's continental interior remain poorly understood. We investigated the current crustal architecture and styles of tectonic deformation of the Nenana and Tanana basins using existing geological, geophysical and geochronological datasets. The results of our study demonstrate that the basements of the basins show strong crustal heterogeneity. The Tanana basin is a relatively shallow (up to 2 km) asymmetrical foreland basin with its southern, deeper side controlled by the northern foothills of the central Alaska Range. Northeast-trending strike-slip faults within the Tanana basin are interpreted as a zone of clockwise crustal block rotation. The Nenana basin has a fundamentally different geometry; it is a deep (up to 8 km), narrow transtensional pull-apart basin that is deforming along the left-lateral Minto Fault. This study identifies two distinct modes of tectonic deformation in central Interior Alaska at present, and provides a basis for modeling the interplay between intraplate stress fields and major structural features that potentially influence the generation of intraplate earthquakes in the region.

Examining the value of global seasonal reference evapotranspiration forecasts to support FEWS NET’s food insecurity outlooks

USGS Publications Warehouse

Shukla, Shraddhanand; McEvoy, Daniel; Hobbins, Michael; Husak, Gregory; Huntington, Justin; Funk, Chris; Macharia, Denis; Verdin, James P.

2017-01-01

The Famine Early Warning Systems Network (FEWS NET) team provides food insecurity outlooks for several developing countries in Africa, Central Asia, and Central America. This study describes development of a new global reference evapotranspiration (ETo) seasonal reforecast and skill evaluation with a particular emphasis on the potential use of this dataset by the FEWS NET to support food insecurity early warning. The ETo reforecasts span the 1982-2009 period and are calculated following ASCE’s formulation of Penman-Monteith method driven by seasonal climate forecasts of monthly mean temperature, humidity, wind speed, and solar radiation from NCEP’s CFSv2 and NASA’s GEOS-5 models. The skill evaluation using deterministic and probabilistic scores, focuses on the December-February (DJF), March-May (MAM), June-August (JJA) and September-November (SON) seasons. The results indicate that ETo forecasts are a promising tool for early warning of drought and food insecurity. Globally, the regions where forecasts are most skillful (correlation >0.35 at lead-2) include Western U.S., northern parts of South America, parts of Sahel region and Southern Africa. The FEWS NET regions where forecasts are most skillful (correlation >0.35 at lead-3) include Northern Sub-Saharan Africa (DJF, dry season), Central America (DJF, dry season), parts of East Africa (JJA, wet Season), Southern Africa (JJA, dry season), and Central Asia (MAM, wet season). A case study over parts of East Africa for the JJA season shows that ETo forecasts in combination with the precipitation forecasts could have provided early warning of recent severe drought events (e.g., 2002, 2004, 2009) that contributed to substantial food insecurity in the region.

The evolutionary dynamics of highly pathogenic avian influenza H5N1 in south-central Vietnam reveals multiple clades evolving from Chinese and Cambodian viruses.

PubMed

Nguyen, Tinh Huu; Than, Van Thai; Thanh, Hien Dang; Nguyen, Van Quang; Nguyen, Kim Hue; Nguyen, Duc Tan; Park, Jong-Hwa; Chung, In Sik; Jeong, Dae Gwin; Chang, Kyu-Tae; Oh, Tae Kwang; Kim, Wonyong

2015-10-01

In Vietnam, highly pathogenic avian influenza (HPAI), such as that caused by H5N1 viruses, is the most highly contagious infectious disease that has been affecting domestic poultry in recent years. Vietnam might be an evolutionary hotspot and a potential source of globally pandemic strains. However, few studies have reported viruses circulating in the south-central region of Vietnam. In the present study, 47 H5N1-positive samples were collected from both vaccinated and unvaccinated poultry farms in the South Central Coast region of Vietnam during 2013-2014, and their genetic diversity was analyzed. A common sequence motif for HPAI virus was identified at HA-cleavage sites in all samples: either RERRRKR/G (clades 2.3.2.1c and 2.3.2.1a) or REGRRKKR/G (clade 1.1.2). Phylogenetic analysis of HA genes identified three clades of HPAI H5N1: 1.1.2 (n=1), 2.3.2.1a (n=1), and 2.3.2.1c (n=45). The phylogenetic analysis indicated that these Vietnamese clades may have evolved from Chinese and Cambodian virus clades isolated in 2012-2013 but are less closely related to the clades detected from the Tyva Republic, Bulgaria, Mongolia, Japan, and Korea in 2009-2011. Detection of the coexistence of virus clades 2.3.2.1 and the very virulent 1.1.2 in the south-central regions suggests their local importance and highlights concerns regarding their spread, both northwards and southwards, as well as the potential for reassortment. The obtained data highlight the importance of regular identification of viral evolution and the development and use of region-specific vaccines. Copyright © 2015 Elsevier Ltd. All rights reserved.

Pattern of Bone Generation after Irradiation in Vascularized Tissue Engineered Constructs.

PubMed

Eweida, Ahmad; Fathi, Ibrahim; Eltawila, Ahmed M; Elsherif, Ahmad M; Elkerm, Yasser; Harhaus, Leila; Kneser, Ulrich; Sakr, Mahmoud F

2018-02-01

 Regenerative medicine modalities provide promising alternatives to conventional reconstruction techniques but are still deficient after malignant tumor excision or irradiation due to defective vascularization.  We investigated the pattern of bone formation in axially vascularized tissue engineering constructs (AVTECs) after irradiation in a study that mimics the clinical scenario after head and neck cancer. Heterotopic bone generation was induced in a subcutaneously implanted AVTEC in the thigh of six male New Zealand rabbits. The tissue construct was made up of Nanobone (Artoss GmbH; Rostock, Germany) granules mixed with autogenous bone marrow and 80 μL of bone morphogenic protein-2 at a concentration of 1.5 μg/μL. An arteriovenous loop was created microsurgically between the saphenous vessels and implanted in the core of the construct to induce axial vascularization. The constructs were subjected to external beam irradiation on postoperative day 20 with a single dose of 15 Gy. The constructs were removed 20 days after irradiation and subjected to histological and immunohistochemical analysis for vascularization, bone formation, apoptosis, and cellular proliferation.  The vascularized constructs showed homogenous vascularization and bone formation both in their central and peripheral regions. Although vascularity, proliferation, and apoptosis were similar between central and peripheral regions of the constructs, significantly more bone was formed in the central regions of the constructs.  The study shows for the first time the pattern of bone formation in AVTECs after irradiation using doses comparable to those applied after head and neck cancer. Axial vascularization probably enhances the osteoinductive properties in the central regions of AVTECs after irradiation. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Chromosomal instability in Streptomyces avermitilis: major deletion in the central region and stable circularized chromosome

PubMed Central

2010-01-01

Background The chromosome of Streptomyces has been shown to be unstable, frequently undergoing gross chromosomal rearrangements. However, the mechanisms underlying this phenomenon remain unclear, with previous studies focused on two chromosomal ends as targets for rearrangements. Here we investigated chromosomal instability of Streptomyces avermitilis, an important producer of avermectins, and characterized four gross chromosomal rearrangement events, including a major deletion in the central region. The present findings provide a valuable contribution to the mechanistic study of genetic instability in Streptomyces. Results Thirty randomly-selected "bald" mutants derived from the wild-type strain all contained gross chromosomal rearrangements of various types. One of the bald mutants, SA1-8, had the same linear chromosomal structure as the high avermectin-producing mutant 76-9. Chromosomes of both strains displayed at least three independent chromosomal rearrangements, including chromosomal arm replacement to form new 88-kb terminal inverted repeats (TIRs), and two major deletions. One of the deletions eliminated the 36-kb central region of the chromosome, but surprisingly did not affect viability of the cells. The other deletion (74-kb) was internal to the right chromosomal arm. The chromosome of another bald mutant, SA1-6, was circularized with deletions at both ends. No obvious homology was found in all fusion sequences. Generational stability analysis showed that the chromosomal structure of SA1-8 and SA1-6 was stable. Conclusions Various chromosomal rearrangements, including chromosomal arm replacement, interstitial deletions and chromosomal circularization, occurred in S. avermitilis by non-homologous recombination. The finding of an inner deletion involving in the central region of S. avermitilis chromosome suggests that the entire Streptomyces chromosome may be the target for rearrangements, which are not limited, as previously reported, to the two chromosomal ends. PMID:20653985

Lake Ontario Shore Protection Study: Literature Review Report.

DTIC Science & Technology

1979-07-01

Rochester Region - Extracted from IJC, May 1976 31 Recreational Facilities and Lake Ontario State Parkway Expressways - Existing and Proposed...Throughout Areas of the Lake Ontario Western and Central Basins and the Genesee and Oswego River Basins - Extracted from the Genesee/Finger Lakes Regional...Planning Board, Nov. 1972 32 Recreational Facilities of the Rochester to St. Lawrence Region - Extracted from IJC, May 1976 33 Aquatic Vegetation

Hydraulic-Geometry Relations for Rivers in Coastal and Central Maine

USGS Publications Warehouse

Dudley, Robert W.

2004-01-01

Hydraulic-geometry relations (curves) were derived for 15 sites on 12 rivers in coastal and central Maine on the basis of site-specific (at-a-station) hydraulic-geometry relations and hydraulic models. At-a-station hydraulic-geometry curves, expressed as well-established power functions, describe the relations between channel geometry, velocity, and flow at a given point on a river. The derived at-a-station hydraulic-geometry curves indicate that, on average, a given increase in flow at a given river cross section in the study area will be nearly equally conveyed by increases in velocity and channel cross-sectional area. Regional curves describing the bankfull streamflow and associated channel geometry as functions of drainage area were derived for use in stream-channel assessment and restoration projects specific to coastal and central Maine. Regional hydraulic-geometry curves were derived by combining hydraulic-geometry information for 15 river cross sections using bankfull flow as the common reference streamflow. The exponents of the derived regional hydraulic-geometry relations indicate that, in the downstream direction, most of the conveyance of increasing contribution of flow is accommodated by an increase in cross-sectional area?with about 50 percent of the increase in flow accommodated by an increase in channel width, and 32 percent by an increase in depth. The remaining 18 percent is accommodated by an increase in streamflow velocity. On an annual-peak-series basis, results of this study indicate that the occurrence of bankfull streamflow for rivers in Maine is more frequent than the 1.5-year streamflow. On a flow-duration basis, bankfull streamflow for rivers in coastal and central Maine is equaled or exceeded approximately 8.1 percent of the time on mean?or about 30 days a year. Bankfull streamflow is roughly three times that of the mean annual streamflow for the sites investigated in this study. Regional climate, snowmelt hydrology, and glacial geology may play important roles in dictating the magnitude and frequency of occurrence of bankfull streamflows observed for rivers in coastal and central Maine.

Human resources for refraction services in Central Nepal.

PubMed

Kandel, Himal; Murthy, G V S; Bascaran, Covadonga

2015-07-01

Uncorrected refractive error is a public health problem globally and in Nepal. Planning of refraction services is hampered by a paucity of data. This study was conducted to determine availability and distribution of human resources for refraction, their efficiency, the type and extent of their training; the current service provision of refraction services and the unmet need in human resources for refraction in Central Nepal. This was a descriptive cross-sectional study. All refraction facilities in the Central Region were identified through an Internet search and interviews of key informants from the professional bodies and parent organisations of primary eye centres. A stratified simple random sampling technique was used to select 50 per cent of refraction facilities. The selected facilities were visited for primary data collection. Face-to-face interviews were conducted with the managers and the refractionists available in the facilities using a semi-structured questionnaire. Data was collected in 29 centres. All the managers (n=29; response rate 100 per cent) and 50 refractionists (Response rate 65.8 per cent) were interviewed. Optometrists and ophthalmic assistants were the main providers of refraction services (n=70, 92.11 per cent). They were unevenly distributed across the region, highly concentrated around urban areas. The median number of refractions per refractionist per year was 3,600 (IQR: 2,400 - 6,000). Interviewed refractionists stated that clients' knowledge, attitude and practice related factors such as lack of awareness of the need for refraction services and/or availability of existing services were the major barriers to the output of refraction services. The total number of refractions carried out in the Central Region per year was 653,176. An additional 170 refractionists would be needed to meet the unmet need of 1,323,234 refractions. The study findings demand a major effort to develop appropriately trained personnel when planning refraction services in the Central Region and in Nepal as a whole. The equitable distribution of the refractionists, their community-outreach services and awareness raising activities should be emphasised. © 2015 The Authors. Clinical and Experimental Optometry © 2015 Optometry Australia.

REGIONAL EMISSIONS OF NITRIC OXIDE (NO) AND CARBON DIOXIDE (CO2) IN AGROECOSYSTEMS IN CENTRAL WEST REGION, BRAZIL.

EPA Science Inventory

The Central West Region in Brazil has been the focus of intense agricultural expansion since the 1970s and, nowadays, a large area of native cerrado has been converted to agricultural use. The expansion was accompanied by intensive use of fertilizer, irrigation and management pra...

Lake Baikal isotope records of Holocene Central Asian precipitation

NASA Astrophysics Data System (ADS)

Swann, George E. A.; Mackay, Anson W.; Vologina, Elena; Jones, Matthew D.; Panizzo, Virginia N.; Leng, Melanie J.; Sloane, Hilary J.; Snelling, Andrea M.; Sturm, Michael

2018-06-01

Climate models currently provide conflicting predictions of future climate change across Central Asia. With concern over the potential for a change in water availability to impact communities and ecosystems across the region, an understanding of historical trends in precipitation is required to aid model development and assess the vulnerability of the region to future changes in the hydroclimate. Here we present a record from Lake Baikal, located in the southern Siberian region of central Asia close to the Mongolian border, which demonstrates a relationship between the oxygen isotope composition of diatom silica (δ18Odiatom) and precipitation to the region over the 20th and 21st Century. From this, we suggest that annual rates of precipitation in recent times are at their lowest for the past 10,000 years and identify significant long-term variations in precipitation throughout the early to late Holocene interval. Based on comparisons to other regional records, these trends are suggested to reflect conditions across the wider Central Asian region around Lake Baikal and highlight the potential for further changes in precipitation with future climate change.

Pharmacogenetic research activity in Central America and the Caribbean: a systematic review

PubMed Central

Céspedes-Garro, Carolina; Naranjo, María-Eugenia G; Rodrigues-Soares, Fernanda; LLerena, Adrián; Duconge, Jorge; Montané-Jaime, Lazara K; Roblejo, Hilda; Fariñas, Humberto; Campos, María de los A; Ramírez, Ronald; Serrano, Víctor; Villagrán, Carmen I; Peñas-LLedó, Eva M

2016-01-01

Aim: The present review was aimed at analyzing the pharmacogenetic scientific activity in Central America and the Caribbean. Materials & methods: A literature search for pharmacogenetic studies in each country of the region was conducted on three databases using a list of the most relevant pharmacogenetic biomarkers including ‘phenotyping probe drugs’ for major drug metabolizing enzymes. The review included 132 papers involving 47 biomarkers and 35,079 subjects (11,129 healthy volunteers and 23,950 patients). Results: The country with the most intensive pharmacogenetic research was Costa Rica. The most studied medical therapeutic area was oncology, and the most investigated biomarkers were CYP2D6 and HLA-A/B. Conclusion: Research activity on pharmacogenetics in Central American and the Caribbean populations is limited or absent. Therefore, strategies to promote effective collaborations, and foster interregional initiatives and research efforts among countries from the region could help for the rational clinical implementation of pharmacogenetics and personalized medicine. PMID:27633613

Monitoring lake level changes by altimetry in the arid region of Central Asia

NASA Astrophysics Data System (ADS)

Zhao, Y.; Liao, J. J.; Shen, G. Z.; Zhang, X. L.

2017-07-01

The study of lake level changes in arid region of Central Asia not only has important significance for the management and sustainable development of inland water resources, but also provides the basis for further study on the response of lakes to climate change and human activities. Therefore, in this paper, eleven typical lakes in Central Asia were observed. The lake edges were obtained through image interpretation using the quasi-synchronous MODIS image, and then water level information with long period (2002-2015) was acquired using ENVISAT/RA-2 and Cryosat-2 satellite borne radar altimeter data. The results show that these 11 lakes all have obvious seasonal changes of water level in a year with a high peak at different month. During 2002 - 2015, their water levels present decreased trend generally except Sarygamysh Lake, Alakol Lake and North Aral Sea. The alpine lakes are most stables, while open lakes’ levels change the most violently and closed lakes change diversely among different lakes.

Conventional tree height-diameter relationships significantly overestimate aboveground carbon stocks in the Central Congo Basin.

PubMed

Kearsley, Elizabeth; de Haulleville, Thales; Hufkens, Koen; Kidimbu, Alidé; Toirambe, Benjamin; Baert, Geert; Huygens, Dries; Kebede, Yodit; Defourny, Pierre; Bogaert, Jan; Beeckman, Hans; Steppe, Kathy; Boeckx, Pascal; Verbeeck, Hans

2013-01-01

Policies to reduce emissions from deforestation and forest degradation largely depend on accurate estimates of tropical forest carbon stocks. Here we present the first field-based carbon stock data for the Central Congo Basin in Yangambi, Democratic Republic of Congo. We find an average aboveground carbon stock of 162 ± 20  Mg  C  ha(-1) for intact old-growth forest, which is significantly lower than stocks recorded in the outer regions of the Congo Basin. The best available tree height-diameter relationships derived for Central Africa do not render accurate canopy height estimates for our study area. Aboveground carbon stocks would be overestimated by 24% if these inaccurate relationships were used. The studied forests have a lower stature compared with forests in the outer regions of the basin, which confirms remotely sensed patterns. Additionally, we find an average soil carbon stock of 111 ± 24  Mg  C  ha(-1), slightly influenced by the current land-use change.

Centrality dependence of particle production in p - Pb collisions at s NN = 5.02 TeV

DOE PAGES

Adam, J.; Adamová, D.; Aggarwal, M. M.; ...

2015-06-08

Here, we report measurements of the primary charged-particle pseudorapidity density and transverse momentum distributions in p–Pb collisions at √s NN = 5.02TeV and investigate their correlation with experimental observables sensitive to the centrality of the collision. Centrality classes are defined by using different event-activity estimators, i.e., charged-particle multiplicities measured in three different pseudorapidity regions as well as the energy measured at beam rapidity (zero degree). The procedures to determine the centrality, quantified by the number of participants (N part) or the number of nucleon-nucleon binary collisions (N coll) are described. We show that, in contrast to Pb-Pb collisions, in p–Pbmore » collisions large multiplicity fluctuations together with the small range of participants available generate a dynamical bias in centrality classes based on particle multiplicity. We propose to use the zero-degree energy, which we expect not to introduce a dynamical bias, as an alternative event-centrality estimator. Based on zero-degree energy-centrality classes, the N part dependence of particle production is studied. Under the assumption that the multiplicity measured in the Pb-going rapidity region scales with the number of Pb participants, an approximate independence of the multiplicity per participating nucleon measured at mid-rapidity of the number of participating nucleons is observed. Furthermore, at high-p T the p–Pb spectra are found to be consistent with the pp spectra scaled by N coll for all centrality classes. Our results represent valuable input for the study of the event-activity dependence of hard probes in p–Pb collisions and, hence, help to establish baselines for the interpretation of the Pb-Pb data.« less

Interior and Ejecta Morphologies of Impact Craters on Ganymede

NASA Astrophysics Data System (ADS)

Barlow, Nadine G.; Klaybor, K.; Katz-Wigmore, J.

2006-09-01

We are utilizing Galileo SSI imagery of Ganymede to classify impact crater interior and ejecta morphologies. Although we are in the early stages of compiling our Catalog of Impact Craters on Ganymede, some interesting trends are beginning to emerge. Few craters display obvious ejecta morphologies, but 68 craters are classified as single layer ejecta and 3 as double layer ejecta. We see no obvious correlation of layered ejecta morphologies with terrain or latitude. All layered ejecta craters have diameters between 10 and 40 km. Sinuosity ("lobateness") and ejecta extent ("ejecta mobility ratio") of Ganymede layered ejecta craters are lower than for martian layered ejecta craters. This suggests less mobility of ejecta materials on Ganymede, perhaps due to the colder temperatures. Interior structures being investigated include central domes, peaks, and pits. 57 dome craters, 212 central peak craters, and 313 central pit craters have been identified. Central domes occur in 50-100 km diameter craters while peaks are found in craters between 20 and 50 km and central pit craters range between 29 and 74 km in diameter. The Galileo Regio region displays higher concentrations of central dome and central pit craters than other regions we have investigated. 67% of central pit craters studied to date are small pits, where the ratio of pit diameter to crater diameter is <0.2. Craters containing the three interior structures preferentially occur on darker terrain units, suggesting that an ice-silicate composition is more conducive to interior feature formation than pure ice alone. Results of this study have important implications not only for the formation of specific interior and ejecta morphologies on Ganymede but also for analogous features associated with Martian impact craters. This research is funded through NASA Outer Planets Research Program Award #NNG05G116G to N. G. Barlow.

Prehospital factors determining regional variation in thrombolytic therapy in acute ischemic stroke.

PubMed

Lahr, Maarten M H; Vroomen, Patrick C A J; Luijckx, Gert-Jan; van der Zee, Durk-Jouke; de Vos, Ronald; Buskens, Erik

2014-10-01

Treatment rates with intravenous tissue plasminogen activator vary by region, which can be partially explained by organizational models of stroke care. A recent study demonstrated that prehospital factors determine a higher thrombolysis rate in a centralized vs. decentralized model in the north of the Netherlands. To investigate prehospital factors that may explain variation in thrombolytic therapy between a centralized and a decentralized model. A consecutive case observational study was conducted in the north of the Netherlands comparing patients arriving within 4·5 h in a centralized vs. decentralized stroke care model. Factors investigated were transportation mode, prehospital diagnostic accuracy, and preferential referral of thrombolysis candidates. Potential confounders were adjusted using logistic regression analysis. A total of 172 and 299 arriving within 4·5 h were enrolled in centralized and decentralized settings, respectively. The rate of transportation by emergency medical services was greater in the centralized model (adjusted odds ratio 3·11; 95% confidence interval, 1·59-6·06). Also, more misdiagnoses of stroke occurred in the central model (P = 0·05). In postal code areas with and without potential preferential referral of thrombolysis candidates due to overlapping catchment areas, the odds of hospital arrival within 4·5 h in the central vs. decentral model were 2·15 (95% confidence interval, 1·39-3·32) and 1·44 (95% confidence interval, 1·04-2·00), respectively. These results suggest that the larger proportion of patients arriving within 4·5 h in the centralized model might be related to a lower threshold to use emergency services to transport stroke patients and partly to preferential referral of thrombolysis candidates. © 2013 The Authors. International Journal of Stroke © 2013 World Stroke Organization.

Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: The N-terminal region is more important than enzymatic activity

PubMed Central

Rouault, Morgane; Rash, Lachlan D.; Escoubas, Pierre; Boilard, Eric; Bollinger, James; Lomonte, Bruno; Maurin, Thomas; Guillaume, Carole; Canaan, Stéphane; Deregnaucourt, Christiane; Schrével, Joseph; Doglio, Alain; Gutiérrez, José María; Lazdunski, Michel; Gelb, Michael H.; Lambeau, Gérard

2009-01-01

Several snake venom secreted phospholipases A2 (sPLA2s) including OS2 exert a variety of pharmacological effects ranging from central neurotoxicity to anti-HIV activity by mechanisms that are not yet fully understood. To conclusively address the role of enzymatic activity and map the key structural elements of OS2 responsible for its pharmacological properties, we have prepared single point OS2 mutants at the catalytic site and large chimeras between OS2 and OS1, an homologous but non toxic sPLA2. Most importantly, we found that the enzymatic activity of the active site mutant H48Q is 500-fold lower than that of the wild-type protein, while central neurotoxicity is only 16-fold lower, providing convincing evidence that catalytic activity is at most a minor factor that determines central neurotoxicity. The chimera approach has identified the N-terminal region (residues 1–22) of OS2, but not the central one (residues 58–89), as crucial for both enzymatic activity and pharmacological effects. The C-terminal region of OS2 (residues 102–119) was found to be critical for enzymatic activity, but not for central neurotoxicity and anti-HIV activity, allowing us to further dissociate enzymatic activity and pharmacological effects. Finally, direct binding studies with the C-terminal chimera which poorly binds to phospholipids while it is still neurotoxic, led to the identification of a subset of brain N-type receptors which may be directly involved in central neurotoxicity. PMID:16669624

Rising prevalence of back pain in Austria: considering regional disparities.

PubMed

Großschädl, Franziska; Stolz, Erwin; Mayerl, Hannes; Rásky, Éva; Freidl, Wolfgang; Stronegger, Willibald J

2016-01-01

Back pain is the most common form of musculoskeletal conditions and leads to high health care costs. Information about geographic variations in highly prevalent diseases/disorders represents important implications for public health planning to face structural challenges. The present study aims to investigate regional trends in the prevalence of back pain and the role of obesity and social inequalities among Austrian adults. A secondary data analysis based on five nationally representative cross-sectional surveys (1973-2007) was carried out (N = 178,818). Back pain was measured as self-reported presence. Obesity (BMI ≥ 30 kg/m²) was adjusted for self-report bias. For the regional analyses, Austria was divided into Western, Central and Eastern Austria. A relative index of inequality (RII) was computed to quantify the extent of social inequality. A continuous rise in back pain prevalence was observed in the three regions and among all investigated subgroups. In 2007 the age-standardised prevalence was similar in Central (36.9 %), Western (35.2 %) and Eastern Austria (34.3 %). The absolute change in back pain prevalence was highest among obese subjects in Central Austria (women: + 29.8 %, men: + 32.5 %). RIIs were unstable during the study period and in 2007 highest in Eastern Austria. Variation and trends in back pain are not attributable to geographic variation in Austria: an assumed East-West gradient in Austria has not been confirmed. Nevertheless our study confirms that back pain dramatically increased in all Austrian regions and investigated subgroups. This worrying trend should be further monitored and public health interventions should be implemented increasingly, especially among obese women and men.

Contributions of the Central Extended Amygdala to Fear and Anxiety.

PubMed

Shackman, Alexander J; Fox, Andrew S

2016-08-03

It is widely thought that phasic and sustained responses to threat reflect dissociable circuits centered on the central nucleus of the amygdala (Ce) and the bed nucleus of the stria terminalis (BST), the two major subdivisions of the central extended amygdala. Early versions of this hypothesis remain highly influential and have been incorporated into the National Institute of Mental Health Research Research Domain Criteria framework. However, new observations encourage a different perspective. Anatomical studies show that the Ce and BST form a tightly interconnected unit, where different kinds of threat-relevant information can be integrated and used to assemble states of fear and anxiety. Imaging studies in humans and monkeys show that the Ce and BST exhibit similar functional profiles. Both regions are sensitive to a range of aversive challenges, including uncertain or temporally remote threat; both covary with concurrent signs and symptoms of fear and anxiety; both show phasic responses to short-lived threat; and both show heightened activity during sustained exposure to diffusely threatening contexts. Mechanistic studies demonstrate that both regions can control the expression of fear and anxiety during sustained exposure to diffuse threat. These observations compel a reconsideration of the central extended amygdala's contributions to fear and anxiety and its role in neuropsychiatric disease. Copyright © 2016 the authors 0270-6474/16/368050-14$15.00/0.

Contributions of the Central Extended Amygdala to Fear and Anxiety

PubMed Central

2016-01-01

It is widely thought that phasic and sustained responses to threat reflect dissociable circuits centered on the central nucleus of the amygdala (Ce) and the bed nucleus of the stria terminalis (BST), the two major subdivisions of the central extended amygdala. Early versions of this hypothesis remain highly influential and have been incorporated into the National Institute of Mental Health Research Research Domain Criteria framework. However, new observations encourage a different perspective. Anatomical studies show that the Ce and BST form a tightly interconnected unit, where different kinds of threat-relevant information can be integrated and used to assemble states of fear and anxiety. Imaging studies in humans and monkeys show that the Ce and BST exhibit similar functional profiles. Both regions are sensitive to a range of aversive challenges, including uncertain or temporally remote threat; both covary with concurrent signs and symptoms of fear and anxiety; both show phasic responses to short-lived threat; and both show heightened activity during sustained exposure to diffusely threatening contexts. Mechanistic studies demonstrate that both regions can control the expression of fear and anxiety during sustained exposure to diffuse threat. These observations compel a reconsideration of the central extended amygdala's contributions to fear and anxiety and its role in neuropsychiatric disease. PMID:27488625

Twentieth Century Regional Climate Change During the Summer in the Central United States Attributed to Agricultural Intensification

NASA Astrophysics Data System (ADS)

Alter, Ross E.; Douglas, Hunter C.; Winter, Jonathan M.; Eltahir, Elfatih A. B.

2018-02-01

Both land use changes and greenhouse gas (GHG) emissions have significantly modified regional climate over the last century. In the central United States, for example, observational data indicate that rainfall increased, surface air temperature decreased, and surface humidity increased during the summer over the course of the twentieth century concurrently with increases in both agricultural production and global GHG emissions. However, the relative contributions of each of these forcings to the observed regional changes remain unclear. Results of both regional climate model simulations and observational analyses suggest that much of the observed rainfall increase—as well as the decrease in temperature and increase in humidity—is attributable to agricultural intensification in the central United States, with natural variability and GHG emissions playing secondary roles. Thus, we conclude that twentieth century land use changes contributed more to forcing observed regional climate change during the summer in the central United States than increasing GHG emissions.

Structural and lithographic study of northern coast ranges and Sacramento Valley, California

NASA Technical Reports Server (NTRS)

Rich, E. I. (Principal Investigator)

1973-01-01

The author has identified the following significant results. The analysis of the ERTS data has disclosed three potentially important linear systems within the northern coast ranges and Sacramento Valley, California. A preliminary geomorphic analysis of the northern coast ranges discloses that the geomorphic characteristics of the area underlain by the Coastal system are much different from those associated with the Central system in the core of the Coast Ranges. Within the Coastal system, or Coastal belt, the drainage networks are moderately fine-textured and have moderately high density. The area associated with the Central system seems to be underlain by an heterogeneous assemblage of rock types which vary in their resistance to erosion. The boundary between the Coastal and Central geomorphic regions is poorly defined and, in a few places, the two regions can be separated only approximately.

Poverty and Ethnicity: A Cross-Country Study of Roma Poverty in Central Europe. World Bank Technical Paper.

ERIC Educational Resources Information Center

Revenga, Ana; Ringold, Dena; Tracy, William Martin

Roma, or "gypsies," are the main poverty risk group in many countries of central and eastern Europe. Living standards for the Roma have deteriorated more severely during the region's transition to a market economy than they have for other population groups, and Roma have been poorly positioned to take advantage of emerging economic and…

Private Tutoring in Eastern Europe and Central Asia: Policy Choices and Implications

ERIC Educational Resources Information Center

Silova, Iveta

2010-01-01

Private tutoring has become increasingly visible in Eastern Europe and Central Asia since the collapse of the socialist bloc in the early 1990s. Yet, this unprecedented growth of private tutoring, in its varied forms and arrangements, has remained largely unnoticed by policymakers in the region. Based on the data from the cross-national studies of…

Annotated zoogeography of non-marine Tardigrada. Part I: Central America.

PubMed

Kaczmarek, Łukasz; Michalczyk, Łukasz; McInnes, Sandra J

2014-02-05

Dividing the world into nine regions, this first paper describes literature records of the limno-terrestrial tardigrades (Tardigrada) reported from Central America. Updating previously published species lists we have revised the taxonomy and provided additional habitat, geographic co-ordinates, and biogeographic comments. It is hoped this work will serve as a reference point and background for further zoogeographic studies.

Overview of the Higher Education Systems in the Tempus Partner Countries: Central Asia. A Tempus Study. Issue 05

ERIC Educational Resources Information Center

Ruffio, Philippe; Heinamaki, Piia; Tchoukaline, Claire Chastang; Manthey, Anja; Reichboth, Veronika

2011-01-01

The main aim of the Tempus programme is to support the modernisation of higher education in Partner Countries outside the European Union. The targeted regions include Eastern Europe, Central Asia, Western Balkans and the Southern Mediterranean, with a total of 29 Partner Countries participating in the programme. In the field of cooperation in…

Challenges for Teachers' Professional Learning for Inclusive Education in Central and Eastern Europe and the Commonwealth of Independent States

ERIC Educational Resources Information Center

Florian, Lani; Becirevic, Majda

2011-01-01

Efforts to prepare teachers and other professionals for inclusive education in the Central and Eastern Europe and the Commonwealth of Independent States (CIS/CEE) region are heavily influenced by the legacy of Soviet defectology (the study of children with disabilities) and Soviet traditions of teacher education. The authors identify some…

Space Radar Image of Tuva, Central Asia

NASA Image and Video Library

1999-04-15

This spaceborne radar image shows part of the remote central Asian region of Tuva, an autonomous republic of the Russian Federation. Tuva is a mostly mountainous region that lies between western Mongolia and southern Siberia.

Desert Dust and Health: A Central Asian Review and Steppe Case Study.

PubMed

Sternberg, Troy; Edwards, Mona

2017-11-03

In Asian deserts environmental and anthropomorphic dust is a significant health risk to rural populations. Natural sources in dry landscapes are exacerbated by human activities that increase the vulnerability to dust and dust-borne disease vectors. Today in Central and Inner Asian drylands, agriculture, mining, and rapid development contribute to dust generation and community exposure. Thorough review of limited dust investigation in the region implies but does not quantify health risks. Anthropogenic sources, such as the drying of the Aral Sea, highlight the shifting dust dynamics across the Central EurAsian steppe. In the Gobi Desert, our case study in Khanbogd, Mongolia addressed large-scale mining's potential dust risk to the health of the local population. Dust traps showed variable exposure to particulates among herder households and town residents; dust density distribution indicated that sources beyond the mine need to be considered when identifying particulate sources. Research suggests that atmospheric dust from multiple causes may enhance human particulate exposure. Greater awareness of dust in greater Central Asia reflects community concern about related health implications. Future human well-being in the region will require more thorough information on dust emissions in the changing environment.

Desert Dust and Health: A Central Asian Review and Steppe Case Study

PubMed Central

Sternberg, Troy; Edwards, Mona

2017-01-01

In Asian deserts environmental and anthropomorphic dust is a significant health risk to rural populations. Natural sources in dry landscapes are exacerbated by human activities that increase the vulnerability to dust and dust-borne disease vectors. Today in Central and Inner Asian drylands, agriculture, mining, and rapid development contribute to dust generation and community exposure. Thorough review of limited dust investigation in the region implies but does not quantify health risks. Anthropogenic sources, such as the drying of the Aral Sea, highlight the shifting dust dynamics across the Central EurAsian steppe. In the Gobi Desert, our case study in Khanbogd, Mongolia addressed large-scale mining’s potential dust risk to the health of the local population. Dust traps showed variable exposure to particulates among herder households and town residents; dust density distribution indicated that sources beyond the mine need to be considered when identifying particulate sources. Research suggests that atmospheric dust from multiple causes may enhance human particulate exposure. Greater awareness of dust in greater Central Asia reflects community concern about related health implications. Future human well-being in the region will require more thorough information on dust emissions in the changing environment. PMID:29099792

Decadal Variation of Precipitation in Saudi Arabia induced by Agricultural Irrigation

NASA Astrophysics Data System (ADS)

Lo, M. H.; Wey, H. W.; Wada, Y.; IM, E. S.; Chien, R. Y.; Wu, R. J.

2017-12-01

Decadal variation of wet-season precipitation has been found in the arid region of central Saudi Arabia. 1980s has been a rather wet decade compared with the decades before. Previous studies have mentioned that the irrigation moisture may contribute to the precipitation anomalies in Saudi Arabia. In the current study, we show from observational data that the contribution of the variation comes mostly from February to May. As the irrigation is a localized forcing, we therefore use the Weather Research and Forecasting (WRF) Model to simulate the response of the land-atmosphere interaction to the wet soil moisture resulted from additional irrigation moisture supply. Preliminary result shows in the irrigated simulation that precipitation in central Saudi Arabia is enhanced, indicating the possible link between irrigation expansion in the 1980s and the decadal precipitation variation over central Saudi Arabia. We propose it is the anomalous convergence induced by irrigation as well as additional moisture that contribute to the enhanced precipitation over heavily irrigation region in the central Saudi Arabian. In addition, analysis on the daily precipitation from the WRF outputs indicates that positive rainfall anomalies tend to happen when there is rainfall originally; that is, irrigation enhances rainfall but not creates rainfall.

A Cooperative Career Education Project Involving the Fayette County Schools, Eastern Kentucky University, and Central Kentucky Vocational Region. Volume I. Final Report.

ERIC Educational Resources Information Center

Jenkins, John D.

The 3-year project was intended to provide for a systematic delivery of career development experiences within each of the three institutions involved--Fayette County Schools, Eastern Kentucky University, and the Central Kentucky Vocational Region--with central activity located in the Fayette County Schools. Major project themes centered on…

Ischaemic heart disease in the former Soviet Union 1990–2015 according to the Global Burden of Disease 2015 Study

PubMed Central

Murphy, Adrianna; Johnson, Catherine O; Roth, Gregory A; Forouzanfar, Mohammad H; Naghavi, Mohsen; Ng, Marie; Pogosova, Nana; Vos, Theo; Murray, Christopher J L; Moran, Andrew E

2018-01-01

Objective The objective of this study was to compare ischaemic heart disease (IHD) mortality and risk factor burden across former Soviet Union (fSU) and satellite countries and regions in 1990 and 2015. Methods The fSU and satellite countries were grouped into Central Asian, Central European and Eastern European regions. IHD mortality data for men and women of any age were gathered from national vital registration, and age, sex, country, year-specific IHD mortality rates were estimated in an ensemble model. IHD morbidity and mortality burden attributable to risk factors was estimated by comparative risk assessment using population attributable fractions. Results In 2015, age-standardised IHD death rates in Eastern European and Central Asian fSU countries were almost two times that of satellite states of Central Europe. Between 1990 and 2015, rates decreased substantially in Central Europe (men −43.5% (95% uncertainty interval −45.0%, −42.0%); women −42.9% (−44.0%, −41.0%)) but less in Eastern Europe (men −5.6% (−9.0, –3.0); women −12.2% (−15.5%, −9.0%)). Age-standardised IHD death rates also varied within regions: within Eastern Europe, rates decreased −51.7% in Estonian men (−54.0, −47.0) but increased +19.4% in Belarusian men (+12.0, +27.0). High blood pressure and cholesterol were leading risk factors for IHD burden, with smoking, body mass index, dietary factors and ambient air pollution also ranking high. Conclusions Some fSU countries continue to experience a high IHD burden, while others have achieved remarkable reductions in IHD mortality. Control of blood pressure, cholesterol and smoking are IHD prevention priorities. PMID:28883037

Trend and variability in a new, reconstructed streamflow dataset for West and Central Africa, and climatic interactions, 1950-2005

NASA Astrophysics Data System (ADS)

Sidibe, Moussa; Dieppois, Bastien; Mahé, Gil; Paturel, Jean-Emmanuel; Amoussou, Ernest; Anifowose, Babatunde; Lawler, Damian

2018-06-01

Over recent decades, regions of West and Central Africa have experienced different and significant changes in climatic patterns, which have significantly impacted hydrological regimes. Such impacts, however, are not fully understood at the regional scale, largely because of scarce hydroclimatic data. Therefore, the aim of this study is to (a) assemble a new, robust, reconstructed streamflow dataset of 152 gauging stations; (b) quantify changes in streamflow over 1950-2005 period, using these newly reconstructed datasets; (c) significantly reveal trends and variability in streamflow over West and Central Africa based on new reconstructions; and (d) assess the robustness of this dataset by comparing the results with those identified in key climatic drivers (e.g. precipitation and temperature) over the region. Gap filling methods applied to monthly time series (1950-2005) yielded robust results (median Kling-Gupta Efficiency >0.75). The study underlines a good agreement between precipitation and streamflow trends and reveals contrasts between western Africa (negative trends) and Central Africa (positive trends) in the 1950s and 1960s. Homogenous dry conditions of the 1970s and 1980s, characterized by reduced significant negative trends resulting from quasi-decadal modulations of the trend, are replaced by wetter conditions in the recent period (1993-2005). The effect of this rainfall recovery (which extends to West and Central Africa) on increased river flows are further amplified by land use change in some Sahelian basins. This is partially offset, however, by higher potential evapotranspiration rates over parts of Niger and Nigeria. Crucially, the new reconstructed streamflow datasets presented here will be available for both the scientific community and water resource managers.

Rejuvenation of antioxidant system in central nervous system of aged rats by grape seed extract.

PubMed

Balu, Muthaiya; Sangeetha, Purushotham; Haripriya, Dayalan; Panneerselvam, Chinnakannu

2005-08-05

Oxidative stress is considered as a major risk factor that contributes to age-related increase in lipid peroxidation and declined antioxidants in the central nervous system during aging. Grape seed extract, one of the bioflavonoid, is widely used for its medicinal properties. In the present study, we evaluated the role of grape seed extract on lipid peroxidation and antioxidant status in discrete regions of the central nervous system of young and aged rats. Male albino rats of Wistar strain were divided into four groups: Group I-control young rats, Group II-young rats treated with grape seed extract (100 mg/kg body weight) for 30 days, Group III-aged control rats and Group IV-aged rats supplemented with grape seed extract (100 mg/kg body weight) for 30 days. Age-associated increase in lipid peroxidation was observed in the spinal cord, cerebral cortex, striatum and the hippocampus regions of aged rats (Group III). Activities of antioxidant enzymes like superoxide dismutase, catalase, glutathione peroxidase and levels of non-enzymic antioxidants like reduced glutathione, Vitamin C and Vitamin E were found to be significantly decreased in all the brain regions studied in aged rats when compared to young rats. However, normalized lipid peroxidation and antioxidant defenses were reported in the grape seed extract-supplemented aged rats. These findings demonstrated that grape seed extract enhanced the antioxidant status and decreased the incidence of free radical-induced lipid peroxidation in the central nervous system of aged rats.

Medicinal plants use in central Togo (Africa) with an emphasis on the timing.

PubMed

Tchacondo, Tchadjobo; Karou, Simplice D; Agban, Amégninou; Bako, Mamouda; Batawila, Komlan; Bawa, Moctar L; Gbeassor, Mensavi; de Souza, Comlan

2012-04-01

Plant-based remedies continue to play a key role in the health care of people in Togo; however, there is a lack of published data in medicinal plants and medical practices of the people in the country. This study was aimed at documenting the plant utilization in the Tem folk medicine in the central region of Togo. An ethnobotanical survey was conducted with traditional healers in the central region of Togo using a semi-structured questionnaire. This study demonstrated that local specialists in the central region of Togo tend to agree with each other in terms of the plants used to treat diabetes (ICF = 0.38), infertility, and abdominal pains (ICF = 0.33), but cite a much more diverse groups of plants to treat problems related to arterial hypertension, sickle cell disease, and abscess. They use 144 herbal concoctions made of 72 plants, distributed among 36 botanical families. The Euphorbiaceae family with eight species was best represented in terms of the number of species. The species with the highest use value were Khaya senegalensis (Desr.) A. Juss. (Meliaceae) (UV = 0.36), Anthocleista djalonensis A. Chev. (Gentianaceae) (UV = 0.27), Trichilia emetica Vahl (Meliaceae) (UV = 0.25), and Sarcocephalus latifolius (Sm.) E. A. Bruce (Rubiaceae) (UV = 0.21). They also rely on the timing in the plant processing and the administration of herbal remedies. All these findings are based on empirical observations; laboratory screenings are needed to check the effectiveness of these plants.

Altered Whole-Brain and Network-Based Functional Connectivity in Parkinson's Disease.

PubMed

de Schipper, Laura J; Hafkemeijer, Anne; van der Grond, Jeroen; Marinus, Johan; Henselmans, Johanna M L; van Hilten, Jacobus J

2018-01-01

Background: Functional imaging methods, such as resting-state functional magnetic resonance imaging, reflect changes in neural connectivity and may help to assess the widespread consequences of disease-specific network changes in Parkinson's disease. In this study we used a relatively new graph analysis approach in functional imaging: eigenvector centrality mapping. This model-free method, applied to all voxels in the brain, identifies prominent regions in the brain network hierarchy and detects localized differences between patient populations. In other neurological disorders, eigenvector centrality mapping has been linked to changes in functional connectivity in certain nodes of brain networks. Objectives: Examining changes in functional brain connectivity architecture on a whole brain and network level in patients with Parkinson's disease. Methods: Whole brain resting-state functional architecture was studied with a recently introduced graph analysis approach (eigenvector centrality mapping). Functional connectivity was further investigated in relation to eight known resting-state networks. Cross-sectional analyses included group comparison of functional connectivity measures of Parkinson's disease patients ( n = 107) with control subjects ( n = 58) and correlations with clinical data, including motor and cognitive impairment and a composite measure of predominantly non-dopaminergic symptoms. Results: Eigenvector centrality mapping revealed that frontoparietal regions were more prominent in the whole-brain network function in patients compared to control subjects, while frontal and occipital brain areas were less prominent in patients. Using standard resting-state networks, we found predominantly increased functional connectivity, namely within sensorimotor system and visual networks in patients. Regional group differences in functional connectivity of both techniques between patients and control subjects partly overlapped for highly connected posterior brain regions, in particular in the posterior cingulate cortex and precuneus. Clinico-functional imaging relations were not found. Conclusions: Changes on the level of functional brain connectivity architecture might provide a different perspective of pathological consequences of Parkinson's disease. The involvement of specific, highly connected (hub) brain regions may influence whole brain functional network architecture in Parkinson's disease.

THE RESPONSE OF METAL-RICH GAS TO X-RAY IRRADIATION FROM A MASSIVE BLACK HOLE AT HIGH REDSHIFT: PROOF OF CONCEPT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aykutalp, A.; Meijerink, R.; Spaans, M.

2013-07-01

Observational studies show that there is a strong link between the formation and evolution of galaxies and the growth of their supermassive black holes. However, the underlying physics behind this observed relation is poorly understood. In order to study the effects of X-ray radiation on black hole surroundings, we implement X-ray-dominated region physics into Enzo and use the radiation transport module Moray to calculate the radiative transfer for a polychromatic spectrum. In this work, we investigate the effects of X-ray irradiation, produced by a central massive black hole (MBH) with a mass of M = 5 Multiplication-Sign 10{sup 4} M{submore » Sun }, on ambient gas with solar and zero metallicity. We find that in the solar metallicity case, the energy deposition rate in the central region ({<=}20 pc) is high due to the high opacity of the metals. Hence, the central temperatures are on the order of 10{sup 5}-10{sup 7} K. Moreover, due to the cooling ability and high intrinsic opacity of solar metallicity gas, column densities of 10{sup 24} cm{sup -2} are reached at a radius of 20 pc from the MBH. These column densities are about three orders of magnitudes higher than in the zero metallicity case. Furthermore, in the zero metallicity case, an X-ray-induced H II region is already formed after 5.8 Myr. This causes a significant outflow of gas ({approx}8 Multiplication-Sign 10{sup 6} M{sub Sun }) from the central region; the gas reaches outflow velocities up to {approx}100 km s{sup -1}. At later times, {approx}23 Myr after we insert the MBH, we find that the solar metallicity case also develops an X-ray-induced H II region, but it is delayed by {approx}17 Myr compared to the zero metallicity case.« less

Nonlinear dynamics of an elliptic vortex embedded in an oscillatory shear flow.

PubMed

Ryzhov, Eugene A

2017-11-01

The nonlinear dynamics of an elliptic vortex subjected to a time-periodic linear external shear flow is studied numerically. Making use of the ideas from the theory of nonlinear resonance overlaps, the study focuses on the appearance of chaotic regimes in the ellipse dynamics. When the superimposed flow is stationary, two general types of the steady-state phase portrait are considered: one that features a homoclinic separatrix delineating bounded and unbounded phase trajectories and one without a separatrix (all the phase trajectories are bounded in a periodic domain). When the external flow is time-periodic, the ensuing nonlinear dynamics differs significantly in both cases. For the case with a separatrix and two distinct types of phase trajectories: bounded and unbounded, the effect of the most influential nonlinear resonance with the winding number of 1:1 is analyzed in detail. Namely, the process of occupying the central stability region associated with the steady-state elliptic critical point by the stability region associated with the nonlinear resonance of 1:1 as the perturbation frequency gradually varies is investigated. A stark increase in the persistence of the central regular dynamics region against perturbation when the resonance of 1:1 associated stability region occupies the region associated with the steady-state elliptic critical point is observed. An analogous persistence of the regular motion occurs for higher perturbation frequencies when the corresponding stability islands reach the central stability region associated with the steady-state elliptic point. An analysis for the case with the resonance of 1:2 is presented. For the second case with only bounded phase trajectories and, therefore, no separatrix, the appearance of much bigger stability islands associated with nonlinear resonances compared with the case with a separatrix is reported.

Chandra Observation of the Cluster of Galaxies MS 0839.9+2938 at z = 0.194: The Central Excess Iron and Type Ia Supernova Enrichment

NASA Astrophysics Data System (ADS)

Wang, Yu; Xu, Haiguang; Zhang, Zhongli; Xu, Yueheng; Wu, Xiang-Ping; Xue, Sui-Jian; Li, Zongwei

2005-09-01

We present the Chandra study of the intermediate-redshift (z=0.194) cluster of galaxies MS 0839.9+2938. By performing both projected and deprojected spectral analyses, we find that the gas temperature is approximately constant at about 4 keV within 130-444 h-170 kpc. In the inner regions, the gas temperature decreases toward the center, reaching <~3 keV in the central 37 h-170 kpc. This implies that the lower and upper limits of the mass deposit rate are 9-34 and 96-126 Msolar yr-1, respectively, within 74 h-170 kpc, where the gas is significantly colder. Along with the temperature drop, we detect a significant inward iron abundance increase from about 0.4 Zsolar in the outer regions to ~=1 Zsolar within the central 37 h-170 kpc. Thus, MS 0839.9+2938 is the cluster showing the most significant central iron excess at z>~0.2. We argue that most of the excess iron should have been contributed by SNe Ia. Using the observed SN Ia rate and stellar mass loss rate, we estimate that the time needed to enrich the central region with excess iron is 6.4-7.9 Gyr, which is similar to those found for nearby clusters. Coinciding with the optical extension of the cD galaxy (up to about 30 h-170 kpc), the observed X-ray surface brightness profile exhibits an excess beyond the distribution expected by either the β model or the Navarro-Frenk-White (NFW) model and can be well fitted with an empirical two-β model that leads to a relatively flatter mass profile in the innermost region.

The nuclear regions of NGC 3311 and NGC 7768 imaged with the Hubble Space Telescope Planetary Camera

NASA Technical Reports Server (NTRS)

Grillmair, Carl J.; Faber, S.M.; Lauer, Tod R.; Baum, William A.; Lynds, Roger C.; O'Neil, Earl J., Jr.; Shaya, Edward J.

1994-01-01

We present high-resolution, V band images of the central regions of the brightest cluster ellipticals NGC 3311 and NGC 7768 taken with the Planetary Camera of the Hubble Space Telescope. The nuclei of both galaxies are found to be obscured by dust, though the morphology of the dust is quite different in the two cases. The dust cloud which obscures the central 3 arcsec of NGC 3311 is complex and irregular, while the central region of NGC 7768 contains a disk of material similar in appearance and scale to that recently observed in HST images of NGC 4261. The bright, relatively blue source detected in ground-based studies of NGC 3311 is marginally resolved and is likely to be a site of ongoing star formation. We examine the distribution of globular clusters in the central regions of NGC 3311. The gradient in the surface density profile of the cluster system is significantly shallower than that found by previous investigators at larger radii. We find a core radius for the cluster distribution of 12 plus or minus 3 kpc, which is even larger than the core radius of the globular cluster system surrounding M87. It is also an order of magnitude larger than the upper limit on the core radius of NGC 3311's stellar light and suggests that the central field-star population and the globular cluster system are dynamically distinct. We briefly discuss possible sources for the cold/warm interstellar material in early-type galaxies. While the issue has not been resolved, models which involve galactic wind failure appear to be mo st naturally consistent with the observations.

Evaluation of the contributions of four components of gross domestic product in various regions in China.

PubMed

Wu, Sanmang; Lei, Yalin; Li, Li

2015-01-01

Four major components influence the growth of the gross domestic product in Chinese provinces: consumption, investment, transnational exports, and inter-provincial exports. By splitting a competitive input-output table into a non-competitive input-output table, this study used an input-output model to measure the contributions of the four components of gross domestic product in various regions in China. We found that international exports drove the growth of the gross domestic product more strongly in the eastern region than in other regions. Investment and inter-provincial exports were the major impetus for gross domestic product growth in the central and western regions. We also found that consumption played a minimal role in driving the growth of the gross domestic product in all regions in China. According to these findings, although various regions can share much in terms of policies to transform the impetus for economic growth, there should be different foci for different regions. Their shared policy is to increase the role of final consumption in stimulating economic growth. Region-specific policies mandate that the eastern region should strengthen the driving force provided by international exports and that the central and western regions should strengthen indigenous growth capabilities by improving scientific innovation, industrial support, and institutional innovation.

Evaluation of the Contributions of Four Components of Gross Domestic Product in Various Regions in China

PubMed Central

Wu, Sanmang; Lei, Yalin; Li, Li

2015-01-01

Four major components influence the growth of the gross domestic product in Chinese provinces: consumption, investment, transnational exports, and inter-provincial exports. By splitting a competitive input-output table into a non-competitive input-output table, this study used an input-output model to measure the contributions of the four components of gross domestic product in various regions in China. We found that international exports drove the growth of the gross domestic product more strongly in the eastern region than in other regions. Investment and inter-provincial exports were the major impetus for gross domestic product growth in the central and western regions. We also found that consumption played a minimal role in driving the growth of the gross domestic product in all regions in China. According to these findings, although various regions can share much in terms of policies to transform the impetus for economic growth, there should be different foci for different regions. Their shared policy is to increase the role of final consumption in stimulating economic growth. Region-specific policies mandate that the eastern region should strengthen the driving force provided by international exports and that the central and western regions should strengthen indigenous growth capabilities by improving scientific innovation, industrial support, and institutional innovation. PMID:25915927

Evaluating scenarios of locations and capacities for vaccine storage in Nigeria.

PubMed

Hirsh Bar Gai, Dor; Graybill, Zachary; Voevodsky, Paule; Shittu, Ekundayo

2018-06-07

Many developing countries still face the prevalence of preventable childhood diseases because their vaccine supply chain systems are inadequate by design or structure to meet the needs of their populations. Currently, Nigeria is evaluating options in the redesign of the country's vaccine supply chain. Using Nigeria as a case study, the objective is to evaluate different regional supply chain scenarios to identify the cost minimizing optimal hub locations and storage capacities for doses of different vaccines to achieve a 100% fill rate. First, we employ a shortest-path optimization routine to determine hub locations. Second, we develop a total cost minimizing routine based on stochastic optimization to determine the optimal capacities at the hubs. This model uses vaccine supply data between 2011 and 2014 provided by Nigeria's National Primary Health Care Development Agency (NPHCDA) on Tuberculosis, Polio, Yellow Fever, Tetanus Toxoid, and Hepatitis B. We find that a two-regional system with no central hub (NC2) cut costs by 23% to achieve a 100% fill rate when compared to optimizing the existing chain of six regions with a central hub (EC6). While the government's leading redesign alternative - no central three-hub system (Gov NC3) - reduces costs by 21% compared with the current EC6, it is more expensive than our NC2 system by 3%. In terms of capacity increases, optimizing the current system requires 42% more capacity than our NC2 system. Although the proposed Gov NC3 system requires the least increase in storage capacity, it requires the most distance to achieve a 100% coverage and about 15% more than our NC2. Overall, we find that improving the current system with a central hub and all its variants, even with optimal regional hub locations, require more storage capacities and are costlier than systems without a central hub. While this analysis prescribes the no central hub with two regions (NC2) as the least cost scenario, it is imperative to note that other configurations have benefits and comparative tradeoffs. Our approach and results offer some guidance for future vaccine supply chain redesigns in countries with similar layouts to Nigeria's. Copyright © 2018 Elsevier Ltd. All rights reserved.

Working Together to Make a Difference in Rural America: North Central Regional Center for Rural Development, 2010 Annual Report

ERIC Educational Resources Information Center

North Central Regional Center for Rural Development, 2011

2011-01-01

The North Central Regional Center for Rural Development (NCRCRD) is one of four regional centers in the United States that have worked to improve the quality of life in rural communities for nearly 40 years. With funding from the USDA National Institute of Food and Agriculture and the land-grant universities in our 12-state region, the NCRCRD…

Elasto-plastic deformation and plate weakening due to normal faulting in the subducting plate along the Mariana Trench

NASA Astrophysics Data System (ADS)

Zhou, Z.; Lin, J.

2017-12-01

We investigated variations in the elasto-plastic deformation of the subducting plate along the Mariana Trench through an analysis of flexural bending, normal fault characteristics, and geodynamic modeling. It was observed that most of the normal faults were initiated along the outer-rise region and grew toward the trench axis with strikes that are mostly subparallel to the local trend of the trench axis. The average trench relief is more than 5 km in the southern region while only about 2 km in the northern and central regions. Fault throws were measured to be significantly greater in the southern region (maximum 320 m) than the northern and central regions (maximum 200 m). The subducting plate was modeled as an elasto-plastic slab subjected to tectonic loading along the trench axis. The "apparent" slab-pull dip angle of the subducting plate, calculated from the ratio of the inverted vertical loading versus horizontal tensional force, was significantly larger in the southern region (51-64°) than in the northern (22-35°) and central (20-34°) regions, which is consistent with the seismologically determined dip angle within the shallow part of the subducting slab. This result suggests that the differences in the plate flexure and normal faulting characteristics along the Mariana Trench might be influenced, at least in part, by significant variations in the dip angle within the shallow part of the subducting plate. Normal faults were modeled to penetrate to a maximum depth of 15, 14, and 25 km in the upper mantle for the northern, central, and southern regions, respectively, which is consistent with the depths of available relocated normal faulting earthquakes in the central region. We calculated that the average reduction of the effective elastic plate thickness Te due to normal faulting is 31% in the southern region, which is almost twice that in both the northern and central regions ( 16%). Furthermore, model results revealed that the stress reduction associated with individual normal faults could also decrease Te locally.

The EDGE-CALIFA Survey: Variations in the Molecular Gas Depletion Time in Local Galaxies

NASA Astrophysics Data System (ADS)

Utomo, Dyas; Bolatto, Alberto D.; Wong, Tony; Ostriker, Eve C.; Blitz, Leo; Sanchez, Sebastian F.; Colombo, Dario; Leroy, Adam K.; Cao, Yixian; Dannerbauer, Helmut; Garcia-Benito, Ruben; Husemann, Bernd; Kalinova, Veselina; Levy, Rebecca C.; Mast, Damian; Rosolowsky, Erik; Vogel, Stuart N.

2017-11-01

We present results from the EDGE survey, a spatially resolved CO(1-0) follow-up to CALIFA, an optical Integral Field Unit survey of local galaxies. By combining the data products of EDGE and CALIFA, we study the variation in molecular gas depletion time (τ dep) on kiloparsec scales in 52 galaxies. We divide each galaxy into two parts: the center, defined as the region within 0.1 {R}25, and the disk, defined as the region between 0.1 and 0.7 {R}25. We find that 14 galaxies show a shorter τ dep (˜1 Gyr) in the center relative to that in the disk (τ dep ˜ 2.4 Gyr), which means the central region in those galaxies is more efficient at forming stars per unit molecular gas mass. This finding implies that the centers with shorter τ dep resemble the intermediate regime between galactic disks and starburst galaxies. Furthermore, the central drop in τ dep is correlated with a central increase in the stellar surface density, suggesting that a shorter τ dep is associated with molecular gas compression by the stellar gravitational potential. We argue that varying the CO-to-H2 conversion factor only exaggerates the central drop of τ dep.

Migratory movements of waterfowl in Central Asia and avian influenza emergence: sporadic transmission of H5N1 from east to west

USGS Publications Warehouse

Iverson, Samuel A.; Gavrilov, Andrei; Katzner, Todd E.; Takekawa, John Y.; Miller, Tricia A.; Hagemeijer, Ward; Mundkur, Taej; Sivananinthaperumal, Balachandran; DeMattos, Carlos C.; Ahmed, Lu'ay S.; Newman, Scott H.

2011-01-01

Waterfowl in the genera Anas and Tadorna are suspected as vectors in the long-distance transmission of highly pathogenic avian influenza H5N1. The former Soviet Republics of Central Asia are situated at an important migratory crossroads for these and other species of birds that bridges regions where the disease is prevalent. However, waterfowl movements through Central Asia are poorly quantified. In this study, historical data derived from over 80 years of bird ringing are combined with recent satellite tracking data to delineate migration routes, movement chronology and habitat use patterns of waterfowl in relation to H5N1 outbreak locations. Results confirm migratory linkage between breeding and moulting areas in northern Kazakhstan and southern Siberia, with nonbreeding areas in the Caspian, Black and eastern Mediterranean Sea basins, as well as with South Asia. However, unlike the situation in neighbouring regions, most notably western China, H5N1 outbreaks have not been recurrent in Central Asia after they were first reported during summer 2005 and spring 2006. These findings have implications in relation to potential sampling biases, species-specific variation in migratory behaviour and continuing regional H5N1 transmission risks.

Crustal insights from gravity and aeromagnetic analysis: Central North Slope, Alaska

USGS Publications Warehouse

Saltus, R.W.; Potter, C.J.; Phillips, J.D.

2006-01-01

Aeromagnetic and gravity data are processed and interpreted to reveal deep and shallow information about the crustal structure of the central North Slope, Alaska. Regional aeromagnetic anomalies primarily reflect deep crustal features. Regional gravity anomalies are more complex and require detailed analysis. We constrain our geophysical models with seismic data and interpretations along two transects including the Trans-Alaska Crustal Transect. Combined geophysical analysis reveals a remarkable heterogeneity of the pre-Mississippian basement. In the central North Slope, pre-Mississippian basement consists of two distinct geophysical domains. To the southwest, the basement is dense and highly magnetic; this basement is likely mafic and mechanically strong, possibly acting as a buttress to basement involvement in Brooks Range thrusting. To the northeast, the central North Slope basement consists of lower density, moderately magnetic rocks with several discrete regions (intrusions?) of more magnetic rocks. A conjugate set of geophysical trends, northwest-southeast and southwest-northeast, may be a factor in the crustal response to tectonic compression in this domain. High-resolution gravity and aeromagnetic data, where available, reflect details of shallow fault and fold structure. The maps and profile models in this report should provide useful guidelines and complementary information for regional structural studies, particularly in combination with detailed seismic reflection interpretations. Future challenges include collection of high-resolution gravity and aeromagnetic data for the entire North Slope as well as additional deep crustal information from seismic, drilling, and other complementary methods. Copyrights ?? 2006. The American Association of Petroleum Geologists. All rights reserved.

Changes in the area of inland lakes in arid regions of central Asia during the past 30 years.

PubMed

Bai, Jie; Chen, Xi; Li, Junli; Yang, Liao; Fang, Hui

2011-07-01

Inland lakes are major surface water resource in arid regions of Central Asia. The area changes in these lakes have been proved to be the results of regional climate changes and recent human activities. This study aimed at investigating the area variations of the nine major lakes in Central Asia over the last 30 years. Firstly, multi-temporal Landsat imagery in 1975, 1990, 1999, and 2007 were used to delineate lake extents automatically based on Normalized Difference Water Index (NDWI) threshold segmentation, then lake area variations were detailed in three decades and the mechanism of these changes was analyzed with meteorological data and hydrological data. The results indicated that the total surface areas of these nine lakes had decreased from 91,402.06 km(2) to 46,049.23 km(2) during 1975-2007, accounting for 49.62% of their original area of 1975. Tail-end lakes in flat areas had shrunk dramatically as they were induced by both climate changes and human impacts, while alpine lakes remained relatively stable due to the small precipitation variations. With different water usage of river outlets, the variations of open lakes were more flexible than those of other two types. According to comprehensive analyses, different types of inland lakes presented different trends of area changes under the background of global warming effects in Central Asia, which showed that the increased human activities had broken the balance of water cycles in this region.

Intraocular distribution of melanin in human, monkey, rabbit, minipig and dog eyes.

PubMed

Durairaj, Chandrasekar; Chastain, James E; Kompella, Uday B

2012-05-01

The purpose of this study was to quantify the melanin pigment content in sclera, choroid-RPE, and retina, three tissues encountered during transscleral drug delivery to the vitreous, in human, rabbit, monkey, minipig, and dog models. Strain differences were assessed in NZW × NZR F1 and Dutch belted rabbits and Yucatan and Gottingen minipigs. The choroid-RPE and retina tissues were divided into central (posterior pole area) and peripheral (away from posterior pole) regions while the sclera was analyzed without such division. Melanin content in the tissues was analyzed using a colorimetric assay. In all species the rank order for pigment content was: choroid-RPE >retina ≥ sclera, except in humans, where scleral melanin levels were higher than retina and central choroid. The melanin content in a given tissue differed between species. Further, while the peripheral tissue pigment levels tended to be generally higher compared to the central regions, these differences were significant in human in the case of choroid-RPE and in human, monkey, and dogs in the case of retina. Strain difference was observed only in the central choroid-RPE region of rabbits (NZW × NZR F1 >Dutch Belted). Species, strain, and regional differences exist in the melanin pigment content in the tissues of the posterior segment of the eye, with Gottingen minipig being closest to humans among the animals assessed. These differences in melanin content might contribute to differences in drug binding, delivery, and toxicity. Copyright © 2012 Elsevier Ltd. All rights reserved.

Contrasting early Holocene temperature variations between monsoonal East Asia and westerly dominated Central Asia

NASA Astrophysics Data System (ADS)

Zhao, Jiaju; An, Chen-Bang; Huang, Yongsong; Morrill, Carrie; Chen, Fa-Hu

2017-12-01

Numerous studies have demonstrated that there are major differences in the timing of maximum Holocene precipitation between the monsoonal East Asia and westerly dominated Central Asia, but it is unclear if the moisture differences are also associated with corresponding temperature contrasts. Here we present the first alkenone-based paleotemperature reconstructions for the past 21 kyr from Lake Balikun, central Asia. We show, unlike the initiation of Holocene warm conditions at ∼11 kyr BP in the monsoon regions, the arid central Asia remained in a glacial-like cold condition prior to 8 kyr BP and experienced abrupt warming of ∼9 °C after the collapse of the Laurentide ice sheet. Comparison with pollen and other geochemical data indicates the abrupt warming is closely associated with major increase in the moisture supply to the region. Together, our multiproxy data indicate ∼2 thousand years delay of temperature and moisture optimum relative to local summer insolation maximum, suggesting major influence of the Laurentide ice sheet and other high latitude ice sheet forcings on the regional atmospheric circulation. In addition, our data reveal a temperature drop by ∼4 °C around 4 kyr BP lasting multiple centuries, coinciding with severe increases in aridity previously reported based on multiproxy data. In contrast, model simulations display a much less pronounced delay in the initiation of Holocene warm conditions, raising unresolved questions about the relative importance of local radiative forcing and high-latitude ice on temperature in this region.

Regional inequalities in self-rated health in Russia: What is the role of social and economic capital?

PubMed

Lyytikäinen, Laura; Kemppainen, Teemu

2016-07-01

Using the data from the European Social Survey (round 6, 2012), this article studies regional inequalities in self-rated health in Russia and examines the role that socio-demographic factors and economic and social capital play in these differences. Also, the regional variation in the determinants of self-rated health is analysed. The article argues that there are considerable and statistically significant unadjusted differences in self-rated health across Russian Federal Districts. We elaborated these differences by regression adjustments, with the result that some of the differences were explained by our predictors and some were amplified. The odds for good self-rated health were lower in the Volga than in Central Russia due to age and socio-economic composition. In contrast, the regression adjustments amplified the differences of the Northwest and the South in comparison to the Central District. The odds for good self-rated health were considerably lower in the Far Eastern part of the country than in the Central District, independently of the adjustments. While social and economic capital predicted good self-rated health at the individual level, they did not explain regional differences. Interaction analyses revealed regional variation in some of the determinants of self-rated health. Most notably, the effects of age, trade union membership and volunteering depended on the regional context. This article argues that the healthcare reforms that transfer funding responsibilities to regional administration may be dangerous for the already less affluent and less healthy rural regions. Thus, regional governance has a growing importance in preventing increases in health inequalities. Copyright © 2016 Elsevier Ltd. All rights reserved.

ECAIM : Air Quality Studies and its Impact in Central Mexico.

NASA Astrophysics Data System (ADS)

Ruiz-Suárez, L. G.; Torres, R.; Garcia-Reynoso, J. A.; Zavala-Hidalgo, J.; Grutter, M.; Delgado-Campos, J.; Molina, L. T.

2014-12-01

Mexico City Metropolitan Area has been the object of several well know intensive campaigns. Since MARI (1991) , IMADA (1997), MCMA 2003 and MILAGRO (2006). The spatial scope of these studies have gone from urban to regional to continental, with the focus on MCMA as an emissions source. During MILAGRO, the influence on MCMA of wildfires and agricultural biomass burning around the megacity was considered. However, around Mexico City a crown of metropolis and middle size cities make a region known as the Central Mexico Regional Crow (CRCM for its acronym in Spanish language) or Central Mexico City Belt. It contains 32 million inhabitants and produces 40% of national gross product. The region undergoes an uncontrolled urban sprawl. Evidence is building-up on complex air pollution transport processes between the air basins within CRCM. However, only MCMA counts with reliable long-term records of criteria pollutants monitoring. Only few intensive campaigns have been done in the air basins surrounding MCMA. ECAIM project has several goals: a) To use ground and satellite observations to assess emissions inventories; b) To use ground and satellite observations to assess the performance of air quality models for the whole region; c) to produce critical levels exceedence maps; d) To produce a preliminary diagnostic of air quality for the CRCM; e) to produce a preliminary estimate of the cost of air pollution within the CRCM. In this work we show the method approach to use the best available information from local AQM networks, field campaigns, satellite observations and modeling to achieve those goals. We show some preliminary results.

A Study of Faculty Perception of the Implementation of the Articulated Faculty Concept. Self-Study Report No. 3. Institutional Research Series 1981.

ERIC Educational Resources Information Center

Zimmerman, Woodford W.

In 1975 and 1981, surveys were conducted at the Lima regional campus of Ohio State University (OSU) to determine the perceptions of tenured and nontenured faculty with regard to the articulated faculty concept, whereby regional campus instructors are fully affiliated with academic departments at the OSU central campus. Faculty were asked to…

Bulgaria, Romania, and Poland: Case Studies of a Changing Region. Fulbright-Hays Summer Seminar Abroad 1996 (Bulgaria and Romania).

ERIC Educational Resources Information Center

Mallory-Boyle, Nancy

This paper presents a unit for government and economics and one for world history on the dramatic regional changes which have occurred in Central and Eastern Europe since the late 1980s. The units can be taught cohesively covering 2-3 weeks or as modules integrated into relevant themes in the curriculum. The "case studies" approach…

Diversity patterns and composition of native and exotic floras in central Chile

NASA Astrophysics Data System (ADS)

Figueroa, Javier A.; Teillier, Sebastián; Castro, Sergio A.

2011-03-01

Floristic changes in the Mediterranean region of central Chile brought about by human impact appear to be shared with other climatic regions, although there is a notable absence of empirical studies and available quantitative evidence for the central Chile region. This study examines the cover, richness and composition of native and exotic plant species in a representative area of central Chile. Through floristic characterization of 33 sites sampled using 40 × 40 m plots distributed along transect on which the two farthest sites were separated by 50 km, the floristic richness and cover patterns, as well as the general land use characteristics were evaluated (native matorral, espinal, abandoned farming field, forest plantations, periurban sites, road sites, river bank, and burnt site). We recorded 327 species of plants; 213 species were native and 114 were exotic. The average number of species was heterogeneous in all sites, showing a greater relative native frequency in those sites with a lower level of anthropic intervention. Except for the matorral, the cover of exotic species was greater than that of native species. No relation was found between richness and cover in relation to the different types of land use. The relationship between cover of native and exotic was negative, although for richness did not show relationship. Results show that the exotic species are limited by resources, although they have not completely displaced the native species. The native and exotic floras respond to different spatial distribution patterns, so their presence makes it possible to establish two facts rarely quantified in central Chile: first, that the exotic flora replaces (but does not necessarily displace) the native flora, and second, that at the same time, because of its greater geographic ubiquity and the abundance levels that it achieves, it contributes to the taxonomic and physiognomic homogenization of central Chile.

TrajGraph: A Graph-Based Visual Analytics Approach to Studying Urban Network Centralities Using Taxi Trajectory Data.

PubMed

Huang, Xiaoke; Zhao, Ye; Yang, Jing; Zhang, Chong; Ma, Chao; Ye, Xinyue

2016-01-01

We propose TrajGraph, a new visual analytics method, for studying urban mobility patterns by integrating graph modeling and visual analysis with taxi trajectory data. A special graph is created to store and manifest real traffic information recorded by taxi trajectories over city streets. It conveys urban transportation dynamics which can be discovered by applying graph analysis algorithms. To support interactive, multiscale visual analytics, a graph partitioning algorithm is applied to create region-level graphs which have smaller size than the original street-level graph. Graph centralities, including Pagerank and betweenness, are computed to characterize the time-varying importance of different urban regions. The centralities are visualized by three coordinated views including a node-link graph view, a map view and a temporal information view. Users can interactively examine the importance of streets to discover and assess city traffic patterns. We have implemented a fully working prototype of this approach and evaluated it using massive taxi trajectories of Shenzhen, China. TrajGraph's capability in revealing the importance of city streets was evaluated by comparing the calculated centralities with the subjective evaluations from a group of drivers in Shenzhen. Feedback from a domain expert was collected. The effectiveness of the visual interface was evaluated through a formal user study. We also present several examples and a case study to demonstrate the usefulness of TrajGraph in urban transportation analysis.

Ground-water quality assessment of the central Oklahoma Aquifer, Oklahoma; project description

USGS Publications Warehouse

Christenson, S.C.; Parkhurst, D.L.

1987-01-01

In April 1986, the U.S. Geological Survey began a pilot program to assess the quality of the Nation's surface-water and ground-water resources. The program, known as the National Water-Quality Assessment (NAWQA) program, is designed to acquire and interpret information about a variety of water-quality issues. The Central Oklahoma aquifer project is one of three ground-water pilot projects that have been started. The NAWQA program also incudes four surface-water pilot projects. The Central Oklahoma aquifer project, as part of the pilot NAWQA program, will develop and test methods for performing assessments of ground-water quality. The objectives of the Central Oklahoma aquifer assessment are: (1) To investigate regional ground-water quality throughout the aquifer in the manner consistent with the other pilot ground-water projects, emphasizing the occurrence and distribution of potentially toxic substances in ground water, including trace elements, organic compounds, and radioactive constituents; (2) to describe relations between ground-water quality, land use, hydrogeology, and other pertinent factors; and (3) to provide a general description of the location, nature, and possible causes of selected prevalent water-quality problems within the study unit; and (4) to describe the potential for water-quality degradation of ground-water zones within the study unit. The Central Oklahoma aquifer, which includes in descending order the Garber Sandstone and Wellington Formation, the Chase Group, the Council Grove Group, the Admire Group, and overlying alluvium and terrace deposits, underlies about 3,000 square miles of central Oklahoma and is used extensively for municipal, industrial, commercial, and domestic water supplies. The aquifer was selected for study by the NAWQA program because it is a major source for water supplies in central Oklahoma and because it has several known or suspected water-quality problems. Known problems include concentrations of arsenic, chromium, selenium, and gross-alpha activity that exceed drinking-water standards. Suspected problems include possible contamination of the aquifer by oil-field brines and drilling fluids, pesticides, industrial chemicals, septic-tank effluent, fertilizers, and leakage from sewage systems and underground tanks used for storage of hydrocarbons. There are four major components of the Central Oklahoma aquifer project. The first component is the collection and analysis of existing information, including chemical, hydrologic, and land-use data. The second component is the geohydrologic and geochemical investigations of the aquifer flow system. The third component is the sampling for a wide variety of inorganic, organic, and radioactive constituents as part a regional survey that will produce a consistent set of data among all ground-water pilot projects. These data can be used to: (1) Define regional ground-water quality within the Central Oklahoma aquifer, and (2) compare water quality in the Central Oklahoma aquifer to the water quality in the other ground-water study units of the NAWQA program. The fourth component is topical studies that will address, in more detail, some of the major water-quality issues pertaining to the aquifer.

Regional nutrient trends in streams and rivers of the United States, 1993-2003

USGS Publications Warehouse

Sprague, Lori A.; Lorenz, David L.

2009-01-01

Trends in flow-adjusted concentrations (indicators of anthropogenic changes) and observed concentrations (indicators of natural and anthropogenic changes) of total phosphorus and total nitrogen from 1993 to 2003 were evaluated in the eastern, central, and western United States by adapting the Regional Kendall trend test to account for seasonality and spatial correlation. The only significant regional trend was an increase in flow-adjusted concentrations of total phosphorus in the central United States, which corresponded to increases in phosphorus inputs from fertilizer in the region, particularly west of the Mississippi River. A similar upward regional trend in observed total phosphorus concentrations in the central United States was not found, likely because precipitation and runoff decreased during drought conditions in the region, offsetting the increased source loading on the land surface. A greater number of regional trends would have been significant if spatial correlation had been disregarded, indicating the importance of spatial correlation modifications in regional trend assessments when sites are not spatially independent.

Genetic Factors and Orofacial Motor Learning Selectively Influence Variability in Central Sulcus Morphology in Chimpanzees (Pan troglodytes).

PubMed

Hopkins, William D; Coulon, Oliver; Meguerditchian, Adrien; Autrey, Michelle; Davidek, Kendall; Mahovetz, Lindsay; Pope, Sarah; Mareno, Mary Catherine; Schapiro, Steven J

2017-05-31

Captive chimpanzees ( Pan troglodytes ) have been shown to learn the use of novel attention-getting (AG) sounds to capture the attention of humans as a means of requesting or drawing their attention to a desired object or food. There are significant individual differences in the use of AG sounds by chimpanzees and, here, we examined whether changes in cortical organization of the central sulcus (CS) were associated with AG sound production. MRI scans were collected from 240 chimpanzees, including 122 that reliably produced AG sounds and 118 that did not. For each subject, the depth of CS was quantified along the superior-inferior plane with specific interest in the inferior portion corresponding to the region of the motor cortex where the mouth and orofacial movements are controlled. Results indicated that CS depth in the inferior, but not superior, portion was significantly greater in chimpanzees that reliably produced AG sounds compared with those who did not. Quantitative genetic analyses indicated that overall CS surface area and depth were significantly heritable, particularly in the superior regions, but less so in the inferior and central portions. Further, heritability in CS depth was altered as a function of acquisition of AG sounds. The collective results suggest that learning to produce AG sounds resulted in region-specific cortical reorganization within the inferior portion of the CS, a finding previously undocumented in chimpanzees or any nonhuman primate. SIGNIFICANCE STATEMENT Recent studies in chimpanzees ( Pan troglodytes ) have shown that some can learn to produce novel sounds by configuring different orofacial movement patterns and these sounds are used in communicatively relevant contexts. Here, we examined the neuromorphological correlates in the production of these sounds in chimpanzees. We show that chimpanzees that have learned to produce these sounds show significant differences in central sulcus (CS) morphology, particularly in the inferior region. We further show that overall CS morphology and regions within the superior portion are significantly heritable, whereas central and inferior portions of the CS are not. The collective findings suggest chimpanzees exhibit cortical plasticity in regions of the brain that were central to the emergence of speech functions in humans. Copyright © 2017 the authors 0270-6474/17/375476-09$15.00/0.

Mineral deposits of Central America, with a section on manganese deposits of Panama

USGS Publications Warehouse

Roberts, Ralph Jackson; Irving, Earl Montgomery; Simons, F.S.

1957-01-01

The mineral deposits of Central America were studied between 1942 and 1945, in cooperation with the United States Department of State and the Foreign Economic Administration. Emphasis was originally placed on the study of strategic-mineral deposits, especially of antimony, chromite, manganese, quartz, and mica, but deposits of other minerals that offered promise of significant future production were also studied. A brief appraisal of the base-metal deposits was made, and deposits of iron ore in Honduras and of lead and zinc ores in Guatemala were mapped. In addition, studies were made of the regional geology of some areas, data were collected from many sources, and a new map of the geology of Central America was compiled.

Forest statistics of central Kentucky

Treesearch

The Forest Survey Organization Central States Forest Experiment Station

1950-01-01

This Survey Release presents the more significant preliminary statistics on the forest area and timber volume for each of the four regions of Central Kentucky. A similar report has been published for the Western Kentucky region and a release for the eastern region will be issued as soon as field work and tabulations are completed. Later an analytical report for the...

From the Ground Up: Growing Entrepreneurship in the North Central Region. RRD 191

ERIC Educational Resources Information Center

Emery, Mary

2008-01-01

More than 300 people in the North Central region added their voices to a discussion on the importance of entrepreneurship to rural community vitality, often traveling long distances to attend one of 11 listening sessions held throughout the region. Among those attending were local leaders, service providers, entrepreneurs, and educators. The…

Central Region: A Report Identifying and Addressing the Educational Needs

ERIC Educational Resources Information Center

US Department of Education, 2011

2011-01-01

This report presents the deliberations of the Central Regional Advisory Committee (RAC), one of 10 RACs established under the Educational Technical Assistance Act of 2002 (20 U.S.C. sections 9601 et. seq.) to assess the educational needs of the region. The committee's report outlines the educational needs across the states of Colorado, Kansas,…

Central Atlantic regional ecological test site

NASA Technical Reports Server (NTRS)

Alexander, R. H.

1972-01-01

The work of the Central Atlantic Regional Ecological Test Site (CARETS) project is discussed. The primary aim of CARETS is to test the hypothesis that data from ERTS-A can be made an integral part of a regional land resources information system, encompassing both inventory of the resource base and monitoring of changes, along with their effects on the quality of the environment. Another objective of the project is to determine scaling factors for developing land use information and regional analysis for regions of any given size.

Infusions of allopregnanolone into the hippocampus and amygdala, but not into the nucleus accumbens and medial prefrontal cortex, produce antidepressant effects on the learned helplessness rats.

PubMed

Shirayama, Yukihiko; Muneoka, Katsumasa; Fukumoto, Makoto; Tadokoro, Shigenori; Fukami, Goro; Hashimoto, Kenji; Iyo, Masaomi

2011-10-01

Patients with depression showed a decrease in plasma and cerebrospinal fluid allopregnanolone (ALLO). But antidepressants increased the contents of ALLO in the rat brain. We examined the antidepressant-like effects of infusion of ALLO into the cerebral ventricle, hippocampus, amygdala, nucleus accumbens, or prefrontal cortex of learned helplessness (LH) rats (an animal model of depression). Of these regions, infusions of ALLO into the cerebral ventricle, the CA3 region of hippocampus, or the central region of amygdala exerted antidepressant-like effects. Infusion of ALLO into the hippocampal CA3 region or the central amygdala did not produce memory deficits or locomotor activation in the passive avoidance and open field tests. It is well documented that ALLO exerts its effects through GABA receptors. Therefore, we examined the antagonistic effects of flumazenil (a GABA receptor antagonist) on the antidepressant-like effects of ALLO. Coinfusion of flumazenil with ALLO into the hippocampal CA3 region, but not into the central amygdala, blocked the antidepressant-like effects of ALLO. However, coinfusion of (+)MK801 (an NMDA receptor antagonist), but not cycloheximide (a protein synthesis inhibitor), blocked the antidepressant-like effects of ALLO in the central amygdala. These results suggest that ALLO exerts antidepressant-like effects in the CA3 region of hippocampus through the GABA system and in the central region of amygdala, dependently on the activation of the glutamatergic mechanisms. Copyright © 2010 Wiley-Liss, Inc.

Central & Eastern Europe and Central Asia: police raids and violence put sex workers at risk of HIV.

PubMed

Crago, A L; Rakhmetova, A; Karadafov, M; Islamova, S; Maslova, I

2008-12-01

In most of the countries of Central & Eastern Europe and Central Asia, sex workers report very high levels of abuse from police, particularly in the context of police raids. In this article, based on an oral presentation at the conference, the Sex Workers' Rights Advocacy Network (SWAN) report on the results of a study conducted among sex workers in several countries in the region. The authors make the link between police violence and general violence, and between violence against sex workers and vulnerability to HIV infection. The authors advance a number of recommendations, including that sex work be decriminalized.

Dynamic functional coupling of high resolution EEG potentials related to unilateral internally triggered one-digit movements.

PubMed

Urbano, A; Babiloni, C; Onorati, P; Babiloni, F

1998-06-01

Between-electrode cross-covariances of delta (0-3 Hz)- and theta (4-7 Hz)-filtered high resolution EEG potentials related to preparation, initiation. and execution of human unilateral internally triggered one-digit movements were computed to investigate statistical dynamic coupling between these potentials. Significant (P < 0.05, Bonferroni-corrected) cross-covariances were calculated between electrodes of lateral and median scalp regions. For both delta- and theta-bandpassed potentials, covariance modeling indicated a shifting functional coupling between contralateral and ipsilateral frontal-central-parietal scalp regions and between these two regions and the median frontal-central scalp region from the preparation to the execution of the movement (P < 0.05). A maximum inward functional coupling of the contralateral with the ipsilateral frontal-central-parietal scalp region was modeled during the preparation and initiation of the movement, and a maximum outward functional coupling during the movement execution. Furthermore, for theta-bandpassed potentials, rapidly oscillating inward and outward relationships were modeled between the contralateral frontal-central-parietal scalp region and the median frontal-central scalp region across the preparation, initiation, and execution of the movement. We speculate that these cross-covariance relationships might reflect an oscillating dynamic functional coupling of primary sensorimotor and supplementary motor areas during the planning, starting, and performance of unilateral movement. The involvement of these cortical areas is supported by the observation that averaged spatially enhanced delta- and theta-bandpassed potentials were computed from the scalp regions where task-related electrical activation of primary sensorimotor areas and supplementary motor area was roughly represented.

Comparisons of evening and morning SMOS passes over the Midwest United States

USDA-ARS?s Scientific Manuscript database

This study investigates differences in the soil moisture product and brightness temperatures between 6 pm and 6 am local solar time, when the SMOS passes for a region in north-central Iowa. This region consists of 69 SMOS pixels and has uniform land-cover, consisting of maize and soybean row crops. ...

Determination of fungicide resistance in Botrytis cinerea from strawberry in the Central Coast Region of California

USDA-ARS?s Scientific Manuscript database

A study was conducted in 2013 to investigate the occurrence of fungicide resistance in Botrytis cinerea populations in California’s northern strawberry growing region; specifically in Watsonville and Salinas. In mid-May, 59 samples consisting of a single diseased fruit or plant part with gray mold s...

Landscape and regional context differentially affect nest parasitism and nest predation for Wood Thrush in central Virginia, USA

EPA Science Inventory

Many empirical studies have shown that forest-breeding songbirds, and neotropical migrants in particular, are found in lower abundance in small patches of forest in the Eastern United States compared to similar, but larger patches in the same region. A common hypothesis for the ...

FREQUENCY DISTRIBUTIONS AND SPATIAL ANALYSIS OF FINE PARTICLE MEASUREMENTS IN ST. LOUIS DURING THE REGIONAL AIR POLLUTION STUDY/REGIONAL AIR MONITORING SYSTEM

EPA Science Inventory

Community, time-series epidemiology typically uses either 24-hour integrated particulate matter (PM) concentrations averaged across several monitors in a city or data obtained at a central monitoring site to relate PM concentrations to human health effects. If 24-hour integrated...

Seeking Synthesis: An Integration Exercise for Teaching Regional Geography

ERIC Educational Resources Information Center

Jones, Mark C.

2014-01-01

This article describes a lesson plan on achieving synthesis, the integration of diverse information sources to create a new whole, vital to the intellectual task of the geographer. This is true regardless of the type of geography being conducted or studied. Synthesis remains central to geography, whether understanding a region, pulling together an…

IR Fine-Structure Line Signatures of Central Dust-Bounded Nebulae in Luminous Infrared Galaxies

NASA Technical Reports Server (NTRS)

Fischer, J.; Allen, R.; Dudley, C. C.; Satyapal, S.; Luhman, M.; Wolfire, M.; Smith, H. A.

2004-01-01

To date, the only far-infrared spectroscopic observations of ultraluminous infrared galaxies have been obtained with the European Space Agency s Infrared Space Observatory Long Wavelength Spectrometer. The spectra of these galaxies are characterized by molecular absorption lines and weak emission lines from photodissociation regions (PDRs), but no far-infrared (greater than 40 microns) lines from ionized regions have been detected. ESA s Herschel Space Observatory, slated for launch in 2007, will likely be able to detect these lines in samples of local and moderate redshift ultra luminous galaxies and to enable measurement of the ionization parameters, the slope of the ionizing continuum, and densities present in the ionized regions of these galaxies. The higher spatial resolution of proposed observatories discussed in this workshop will enable isolation of the central regions of local galaxies and detection of these lines in high-redshift galaxies for study of the evolution of galaxies. Here we discuss evidence for the e.ects of absorption by dust within ionized regions and present the spectroscopic signatures predicted by photoionization modeling of dust-bounded regions.

Forest fires in Himalayan region during 2016 - Aerosol load and smoke plume heights detection by multi sensor observations

NASA Astrophysics Data System (ADS)

Kumar, S.; Dumka, U. C.

2017-12-01

The forest fires are common events over the Central Himalayan region during the pre-monsoon season (March - June) of every year. Forest fire plays a crucial role in governing the vegetation structure, ecosystem, climate change as well as in atmospheric chemistry. In regional and global scales, the combustion of forest and grassland vegetation releases large volumes of smoke, aerosols, and other chemically active species that significantly influence Earth's radiative budget and atmospheric chemistry, impacting air quality and risks to human health. During the year 2016, massive forest fires have been recorded over the Central Himalayan region of Uttarakhand which continues for several weeks. To study this event we used the multi-satellite observations of aerosols and pollutants during pre-fire, fire and post-fire period over the central Himalayan region. The data used in this study are active fire count and aerosol optical depth (AOD) from MODerate-resolution Imaging Spectroradiometer (MODIS), aerosol index and gases pollutants from Ozone Monitoring Instrument (OMI), along with vertical profiles of aerosols and smoke plume height information from Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO). The result shows that the mean fire counts were maximum in April. The daily average AOD value shows an increasing trend during the fire events. The mean value of AOD before the massive fire (25 April), during the fire (30 April) and post fire (5 May) periods are 0.3, 1.2 and 0.6 respectively. We find an increasing trend of total columnar NO2 over the Uttarakhand region during the massive fire event. Space-born Lidar (CALIPSO) retrievals show the extent of smoke plume heights beyond the planetary boundary layer up to 6 km during the peak burning day (April 30). The HYSPLIT air mass forward trajectory shows the long-range transportation of smoke plumes. The results of the present study provide valuable information for addressing smoke plume and aerosol transport in the Himalayan region. The implication of this study and the details of the analysis will be presented during the conference.

Reversing cooling flows with AGN jets: shock waves, rarefaction waves and trailing outflows

NASA Astrophysics Data System (ADS)

Guo, Fulai; Duan, Xiaodong; Yuan, Ye-Fei

2018-01-01

The cooling flow problem is one of the central problems in galaxy clusters, and active galactic nucleus (AGN) feedback is considered to play a key role in offsetting cooling. However, how AGN jets heat and suppress cooling flows remains highly debated. Using an idealized simulation of a cool-core cluster, we study the development of central cooling catastrophe and how a subsequent powerful AGN jet event averts cooling flows, with a focus on complex gasdynamical processes involved. We find that the jet drives a bow shock, which reverses cooling inflows and overheats inner cool-core regions. The shocked gas moves outward in a rarefaction wave, which rarefies the dense core and adiabatically transports a significant fraction of heated energy to outer regions. As the rarefaction wave propagates away, inflows resume in the cluster core, but a trailing outflow is uplifted by the AGN bubble, preventing gas accumulation and catastrophic cooling in central regions. Inflows and trailing outflows constitute meridional circulations in the cluster core. At later times, trailing outflows fall back to the cluster centre, triggering central cooling catastrophe and potentially a new generation of AGN feedback. We thus envisage a picture of cool cluster cores going through cycles of cooling-induced contraction and AGN-induced expansion. This picture naturally predicts an anti-correlation between the gas fraction (or X-ray luminosity) of cool cores and the central gas entropy, which may be tested by X-ray observations.

Reconstructing time series water volumes of drying lakes in Central Asia with ZY-3 stereo remote sensing data

NASA Astrophysics Data System (ADS)

Li, J.; Warner, T.; Bao, A.

2017-12-01

Central Asia is one of the world most vulnerable areas responding to global change. Lakes in arid regions of Central Asia remain sensitive to climatic change and fluctuate with temperature and precipitation variations. Study showed that some central asian inland lakes in showed a trend of area shrinkage or extinct in the last decades. Quantitative analysis of lake volume changes in spatio-temporal processes will improve our understanding water resource utilization in arid regions and their responses to regional climate change. However, due to the lack of lake bathmetry or observation data, the volumes of these lakes remain unknown. In this paper, three lakes, such as Chaiwopu lake, Alik Lake and Selectyteniz Lake in Central Asia are used to reconstruct lake volume changes. Firstly, stereo mapping technologies derived from ZY-3 high resolution data are used to map the high-precision 3-D lake bathmetry, so as to create "Area-Level-Volume" based on contours of lake bathmetry. Secondly, time series lake areas in the last 50 years are mapped with multi-source and multi-temporal remote sensing images. Based on lake storage curves and time series lake areas, lake volumes in the last 5 decades can be reconstructed, and the spatio-temporal characteristics of lake volume changes and their mechanisms are also analyzed. The results showed that the high-precision lake hydrological elements are reconstructed on arid drying lakes through the application of stereo mapping technology in remote sensing.

Attribution of the 2015 record high sea surface temperatures over the central equatorial Pacific and tropical Indian Ocean

NASA Astrophysics Data System (ADS)

Park, In-Hong; Min, Seung-Ki; Yeh, Sang-Wook; Weller, Evan; Kim, Seon Tae

2017-04-01

This study assessed the anthropogenic contribution to the 2015 record-breaking high sea surface temperatures (SSTs) observed in the central equatorial Pacific and tropical Indian Ocean. Considering a close link between extreme warm events in these regions, we conducted a joint attribution analysis using a fraction of attributable risk approach. Probability of occurrence of such extreme anomalies and long-term trends for the two oceanic regions were compared between CMIP5 multi-model simulations with and without anthropogenic forcing. Results show that the excessive warming in both regions is well beyond the range of natural variability and robustly attributable to human activities due to greenhouse gas increase. We further explored associated mechanisms including the Bjerknes feedback and background anthropogenic warming. It is concluded that background warming was the main contribution to the 2015 extreme SST event over the central equatorial Pacific Ocean on a developing El Niño condition, which in turn induced the extreme SST event over the tropical Indian Ocean through the atmospheric bridge effect.

Anorexia Nervosa and Body Fat Distribution: A Systematic Review

PubMed Central

El Ghoch, Marwan; Calugi, Simona; Lamburghini, Silvia; Dalle Grave, Riccardo

2014-01-01

The aim of this paper was to conduct a systematic review of body fat distribution before and after partial and complete weight restoration in individuals with anorexia nervosa. Literature searches, study selection, method development and quality appraisal were performed independently by two authors, and data was synthesized using a narrative approach. Twenty studies met the inclusion criteria and were consequently analyzed. The review had five main findings. First, during anorexia nervosa adolescent females lose more central body fat, while adult females more peripheral fat. Second, partial weight restoration leads to greater fat mass deposition in the trunk region than other body regions in adolescent females. Third, after short-term weight restoration, whether partial or complete, adults show a central adiposity phenotype with respect to healthy age-matched controls. Fourth, central fat distribution is associated with increased insulin resistance, but does not adversely affect eating disorder psychopathology or cause psychological distress in female adults. Fifth, the abnormal central fat distribution seems to normalize after long-term maintenance of complete weight restoration, indicating that preferential central distribution of body fat is a transitory phenomenon. However, a discrepancy in the findings has been noted, especially between adolescents and adults; besides age and gender, these appear to be related to differences in the methodology and time of body composition assessments. The PROSPERO Registry—Anorexia Nervosa and Body Fat Distribution: A Systematic Review (CRD42014008738). PMID:25251296

Intraseasonal variability of organized convective systems in the Central Andes: Relationship to Regional Dynamical Features

NASA Astrophysics Data System (ADS)

Mohr, K. I.; Slayback, D. A.; Nicholls, S.; Yager, K.

2013-12-01

The Andes extend from the west coast of Colombia (10N) to the southern tip of Chile (53S). In southern Peru and Bolivia, the Central Andes is split into separate eastern and western cordilleras, with a high plateau (≥ 3000 m), the Altiplano, between them. Because 90% of the Earth's tropical mountain glaciers are located in the Central Andes, our study focuses on this region, defining its zonal extent as 7S-21S and the meridional extent as the terrain 1000 m and greater. Although intense convection occurs during the wet season in the Altiplano, it is not included in the lists of regions with frequent or the most intense convection. The scarcity of in-situ observations with sufficient density and temporal resolution to resolve individual storms or even mesoscale-organized cloud systems and documented biases in microwave-based rainfall products in poorly gauged mountainous regions have impeded the development of an extensive literature on convection and convective systems in this region. With the tropical glaciers receding at unprecedented rates, leaving seasonal precipitation as an increasingly important input to the water balance in alpine valley ecosystems and streams, understanding the nature and characteristics of the seasonal precipitation becomes increasingly important for the rural economies in this region. Previous work in analyzing precipitation in the Central Andes has emphasized interannual variability with respect to ENSO, this is the first study to focus on shorter scale variability with respect to organized convection. The present study took advantage of the University of Utah's Precipitation Features database compiled from 14 years of TRMM observations (1998-2012), supplemented by field observations of rainfall and streamflow, historical gauge data, and long-term WRF-simulations, to analyze the intraseasonal variability of precipitating systems and their relationship regional dynamical features such as the Bolivian High. Through time series and wavelet analysis, we found an important 8-10 day cycle related to but lagging convective surges in the Amazon basin and enhanced upper-level cyclonic flow around the Bolivian High. The majority of the organized convection in the region tended to be weak (< 5 mm/hr rain rates) and shallow (< 12 km). The timing of response (i.e., formation and distribution of organized convection) due to changes in moisture transport around the Bolivian High was similar in the wetter eastern and drier western cordilleras of the Central Andes. The response to upper level moisture transport was modulated by local soil moisture and elevation slope and aspect, with higher elevation, eastern facing peaks having a stronger response than western-facing and lower elevation areas. Streamflow data support the hypothesis that the majority of the light rainfall infiltrates the shallow sub-surface, rather than contributing to surface channel runoff, helping to sustain the high altitude peatlands in the Andean valleys.

Geologic map of the Cochetopa Park and North Pass Calderas, northeastern San Juan Mountains, Colorado

USGS Publications Warehouse

Lipman, Peter W.

2012-01-01

The San Juan Mountains in southwestern Colorado have long been known as a site of exceptionally voluminous mid-Tertiary volcanism, including at least 22 major ignimbrite sheets (each 150-5,000 km3) and associated caldera structures active at 33-23 Ma. Recent volcanologic and petrologic studies in the San Juan region have focused mainly on several ignimbrite-caldera systems: the southeastern area (Platoro complex), western calderas (Uncompahgre-Silverton-Lake City), and the central cluster (La Garita-Creede calderas). Far less studied has been the northeastern San Juan region, which occupies a transition between earlier volcanism in central Colorado and large-volume younger ignimbrite-caldera foci farther south and west. The present map is based on new field coverage of volcanic rocks in seventeen 7.5' quadrangles in northeastern parts of the volcanic field, high-resolution age determinations for 120 new sites, and petrologic studies involving several hundred new chemical analyses. This mapping and the accompanying lab results (1) document volcanic evolution of the previously unrecognized North Pass caldera and the morphologically beautifully preserved but enigmatic Cochetopa basin, including unique features not previously described from ignimbrite calderas elsewhere; (2) provide evidence for a more rapid recurrence of large ignimbrite eruptions than previously known elsewhere; (3) quantify the regional time-space-volume progression from the earlier Sawatch magmatic trend southward into the San Juan region; and (4) permit more rigorous comparison between the broad mid-Tertiary magmatic belt in the western U.S. Cordillera and the type continental-margin arc volcanism in the central Andes.

Geochemical maps of stream sediments in central Colorado, from New Mexico to Wyoming

USGS Publications Warehouse

Eppinger, Robert G.; Giles, Stuart A.; Klein, Terry L.

2015-01-01

The U.S. Geological Survey has completed a series of geologic, mineral resource, and environmental assessment studies in the Rocky Mountains of central Colorado, from Leadville eastward to the range front and from New Mexico to the Wyoming border. Regional stream-sediment geochemical maps, useful for assessing mineral resources and environmental effects of historical mining activities, were produced as part of the study. The data portrayed in this 56-parameter portfolio of landscape geochemical maps serve as a geochemical baseline for the region, indicate element abundances characteristic of various lithologic terranes, and identify gross anthropogenic effects of historical mining. However, although reanalyzed in this study by modern, sensitive methods, the majority of the stream-sediment samples were collected in the 1970s. Thus, metal concentrations portrayed in these maps represent stream-sediment geochemistry at the time of collection.

Cost-benefit analysis of central softening for production of drinking water.

PubMed

Van der Bruggen, B; Goossens, H; Everard, P A; Stemgée, K; Rogge, W

2009-01-01

Softening drinking water before distribution yields advantages with environmental impact, such as lower household products consumption, less scaling in piping and machines, and the avoidance of decentralized, domestic softeners. Central softening is under consideration in Flanders by the largest water supplier, VMW (Dutch acronym for "Flemish Company for Water Supply"), to deliver soft (15 degrees F) water to their customers. A case study is presented for a region with hard water (47 degrees F). The chosen technique is the pellet reactor, based on precipitation of CaCO(3) by NaOH addition. This softening operation has possibly large impact on the environment and the water consumption pattern. A cost-benefit analysis has been made to estimate the added value of central softening, by investigating the impact on the drinking water company, on their customers, on employment, on environment, on health, etc. The analysis for the region of study revealed benefits for customers which were higher than the costs for the drinking water company. However, pricing of drinking water remains an important problem. A sensitivity analysis of these results has also been made, to evaluate the impact of important hypothesis, and to be able to expand this study to other regions. The conclusions for this part show that softening is beneficial if water hardness is to be decreased by at least 5 degrees F.

Preliminary report on seismic-reflection studies of crustal structure in the western, central, and southern United States

USGS Publications Warehouse

Roller, J.C.; Strozier, O.P.; Jackson, W.H.; Healy, J.H.

1963-01-01

During 1963 the U.S. Geological Survey, with the assistance of United ElectroDynamics, Inc., recorded five separate reversed seismic profiles. In addition to these profiles, the U.S. Geological Survey participated in a seismic-calibration program for the DRIBBLE experiment at Tatum Dome, Mississippi, a 20,000-pound shot near Dexter, Missouri, and in a cooperative seismic experiment in the Lake Superior region. This work is a continuation of the program started in 1961; however, the emphasis has shifted from a detailed study of the earth's crust in the western United States to a study of crustal structure in various geologic environments including the Wyoming thrust belt, Colorado Plateau, Central Lowlands, the Gulf Coastal Plain, and the southern part of the Canadian Shield. The U.S. Geological Survey has now completed reversed seismic-refraction profiles in nine different geologic provinces. These data present a promising indication that it may be possible to predict the crustal structure in unexplored areas by considering the regional geologic and physiographic environment. The following Pn velocities have been determined: 8.2 km/sec in the Wyoming thrust belt, 7.9 km/sec in the Colorado Plateau, 8.1 km/sec in the Central Lowlands, and about 8.2 km/sec in the Gulf Coastal Plain. The data from the Lake Superior region have not yet been interpreted.

Experimental study of the heated contact line region for a pure fluid and binary fluid mixture in microgravity.

PubMed

Nguyen, Thao T T; Kundan, Akshay; Wayner, Peter C; Plawsky, Joel L; Chao, David F; Sicker, Ronald J

2017-02-15

Understanding the dynamics of phase change heat and mass transfer in the three-phase contact line region is a critical step toward improving the efficiency of phase change processes. Phase change becomes especially complicated when a fluid mixture is used. In this paper, a wickless heat pipe was operated on the International Space Station (ISS) to study the contact line dynamics of a pentane/isohexane mixture. Different interfacial regions were identified, compared, and studied. Using high resolution (50×), interference images, we calculated the curvature gradient of the liquid-vapor interface at the contact line region along the edges of the heat pipe. We found that the curvature gradient in the evaporation region increases with increasing heat flux magnitude and decreasing pentane concentration. The curvature gradient for the mixture case is larger than for the pure pentane case. The difference between the two cases increases as pentane concentration decreases. Our data showed that the curvature gradient profile within the evaporation section is separated into two regions with the boundary between the two corresponding to the location of a thick, liquid, "central drop" region at the point of maximum internal local heat flux. We found that the curvature gradients at the central drop and on the flat surfaces where condensation begins are one order of magnitude smaller than the gradients in the corner meniscus indicating the driving forces for fluid flow are much larger in the corners. Copyright © 2016 Elsevier Inc. All rights reserved.

The current prevalence and regional disparities in general and central obesity among children and adolescents in Shandong, China.

PubMed

Zhang, Ying-Xiu; Wang, Zhao-Xia; Zhao, Jin-Shan; Chu, Zun-Hua

2017-01-15

Childhood obesity has increased dramatically during the past decades, both in developing and developed countries. The present study examined the prevalence and regional disparities in general and central obesity among children and adolescents in Shandong, China. A total of 30,459 students (15,249 boys and 15,210 girls) aged 7-18years participated in the study. Height, weight and waist circumference (WC) of all subjects were measured, body mass index (BMI) and waist-to-height ratio (WHtR) were calculated. The BMI cutoff points recommended by the International Obesity Task Force (IOTF) were used to define general obesity. Central obesity was defined as WHtR≥0.5. Both BMI and WHtR were used to define three types of obesity as follows: general obesity only, central obesity only and combined obesity. The overall prevalences of general obesity only, central obesity only and combined obesity were 10.99, 8.47 and 8.70% for boys and 9.47, 5.12 and 3.19% for girls, respectively. The sum of the prevalence of the three types of obesity was 28.16% for boys and 17.78% for girls, boys had higher prevalence of obesity than girls (P<0.01). Substantial urban-rural and regional disparities exist in childhood obesity, children and adolescents from urban, coastal and high socioeconomic status (SES) districts showed a higher prevalence of obesity than their counterparts from rural, inland and low SES districts (P<0.01). The widespread prevalence of obesity in children and adolescents has become an important public health concern. Results from this study also suggested that the additional measurement of WC (WHtR) is better than BMI alone to identify obese individuals, distinguishing the types of obesity and examining the prevalence of various types of obesity is useful in practice. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Interaction between active tectonics, erosion and diapirism, a case study from Habble-Rud in Southern Central Alborz (Northern Iran)

NASA Astrophysics Data System (ADS)

Jaberi, Maryam; Ghassemi, Mohammad R.; Shayan, Siavosh; Yamani, Mojtaba; Zamanzadeh, Seyed Mohammad

2018-01-01

The Alborz mountain chain is a region of active deformation within the Arabia-Eurasia continental collision zone. The southern part of central Alborz Mountains, in the north of Iran, represents complex tectonics because it is located at the border of two developing continental sedimentary basins between southern central Alborz and Central Iran. An arid and semi-arid climate, a large extent of Quaternary sediments, rugged topography, salt domes and faults with historical seismicity influence the Habble-Rud River catchment. In the present research, a number of tectonic geomorphologic indices were extracted from satellite imagery and 10 m DEM (digital elevation model) data in order to identify relative tectonic activity within the basin. The indices include: stream length-gradient index (Sl), drainage basin asymmetry (Af), index of mountain front sinuosity (Smf), hypsometric integral (Hi), index of drainage basin shape (Bs), ratio of valley-floor width to valley height (Vf), and fault density (Fd). Due to the presence of heterogeneous indices for all sections of the catchment causing large extension of Habble-Rud (3260 km2), all of the variables such as extremely erodible formations, faults and folds and salt tectonics on the Southern part; were put into a matrix table. As a new approach, the variables were put into the SAW (simple additive model) model as one of MADM (multi-attribute decision-making models) techniques. The study area was divided into four regions according to the values of SAW. These classes include very high (%11), high (48.3%), moderate (34.7%), and low activity (3.4%). The result of the model suggests that the study area is located on a changing tectonic trend in central Alborz from NW-SE to NE-SW. The regions with high relative tectonic activity in HR catchment correspond to the active Garmsar and Sorkhe-Kalout faults and diapirs.

Bootstrapping data envelopment analysis of efficiency and productivity of county public hospitals in Eastern, Central, and Western China after the public hospital reform.

PubMed

Wang, Man-Li; Fang, Hai-Qing; Tao, Hong-Bing; Cheng, Zhao-Hui; Lin, Xiao-Jun; Cai, Miao; Xu, Chang; Jiang, Shuai

2017-10-01

China implemented the public hospital reform in 2012. This study utilized bootstrapping data envelopment analysis (DEA) to evaluate the technical efficiency (TE) and productivity of county public hospitals in Eastern, Central, and Western China after the 2012 public hospital reform. Data from 127 county public hospitals (39, 45, and 43 in Eastern, Central, and Western China, respectively) were collected during 2012-2015. Changes of TE and productivity over time were estimated by bootstrapping DEA and bootstrapping Malmquist. The disparities in TE and productivity among public hospitals in the three regions of China were compared by Kruskal-Wallis H test and Mann-Whitney U test. The average bias-corrected TE values for the four-year period were 0.6442, 0.5785, 0.6099, and 0.6094 in Eastern, Central, and Western China, and the entire country respectively, with average non-technical efficiency, low pure technical efficiency (PTE), and high scale efficiency found. Productivity increased by 8.12%, 0.25%, 12.11%, and 11.58% in China and its three regions during 2012-2015, and such increase in productivity resulted from progressive technological changes by 16.42%, 6.32%, 21.08%, and 21.42%, respectively. The TE and PTE of the county hospitals significantly differed among the three regions of China. Eastern and Western China showed significantly higher TE and PTE than Central China. More than 60% of county public hospitals in China and its three areas operated at decreasing return scales. There was a considerable space for TE improvement in county hospitals in China and its three regions. During 2012-2015, the hospitals experienced progressive productivity; however, the PTE changed adversely. Moreover, Central China continuously achieved a significantly lower efficiency score than Eastern and Western China. Decision makers and administrators in China should identify the causes of the observed inefficiencies and take appropriate measures to increase the efficiency of county public hospitals in the three areas of China, especially in Central China.

Simulating soybean productivity under rainfed conditions for major soil types using APEX model in East Central Mississippi

Treesearch

Bangbang Zhang; Gary Feng; John J. Read; Xiangbin Kong; Ying Ouyang; Ardeshir Adeli; Johnie N. Jenkins

2016-01-01

Knowledge of soybean yield constraints under rainfed conditions on major soil types in East CentralMississippi would assist growers in the region to effectively utilize the benefits of water/irrigation man-agement. The objectives of this study were to use the Agricultural Policy/Environmental eXtender (APEX)agro-ecosystem model to simulate rainfed soybean grain yield (...

Current irrigation practices in the central United States reduce drought and extreme heat impacts for maize and soybean, but not for wheat

USDA-ARS?s Scientific Manuscript database

In this study, we assessed the adaptive effects of irrigation on climatic risks for three crops (maize, soybean, and wheat) at the regional scale from 1981 to 2012 in the Central US. Based on yields of 183 counties for maize, 121 for soybean and 101 for wheat, statistical models were developed for i...

The ant (Hymenoptera: Formicidae) fauna of the cedar glades and xeric limestone prairies of the Central Basin of Tennessee

USDA-ARS?s Scientific Manuscript database

Ants may be the most thoroughly documented group of insects inhabiting the cedar glades of the Central Basin of Tennessee with two studies conducted in the late 1930s reporting ants found in cedar glades of the region. To compare the ant fauna of modern cedar glades with the lists produced in earlie...

Turkey's Educational Policies in Central Asia and Caucasia: Perceptions of Policy Makers and Experts

ERIC Educational Resources Information Center

Akcali, Pinar; Engin-Demir, Cennet

2012-01-01

The purpose of this study is to analyze the educational policies of Turkey in Central Asia and Caucasia in the post-Soviet era in terms of their successes and failures as perceived by some of the relevant professional policy makers in this field as well as experts from various think-tank institutions in Turkey who are interested in the region.…

A coupled remote sensing and the Surface Energy Balance based algorithms to estimate actual evapotranspiration over the western and southern regions of Saudi Arabia

NASA Astrophysics Data System (ADS)

Mahmoud, Shereif H.; Alazba, A. A.

2016-07-01

In countries with absolute water scarcity such as the Kingdom of Saudi Arabia (KSA), large-scale actual evapotranspiration estimation is of great concern in water use practices. Herein, spatial and temporal distribution of actual evapotranspiration (AET) in the western and southern regions of KSA during 1992-2014 was estimated using the SEBAL model with field observations. Zonal statistics for each land use-cover type were also identified, in order to understand their effects on water consumption. In addition, daily and seasonal water consumption for major crops was computed. Results revealed a gradual increase in monthly AET values from January to April and subsequent decline from May to December. The maximum monthly AET values were observed for irrigated cropland in southwestern, central, and southeastern regions of Asir Province, central and southwestern regions of Al-Baha Province, central and the plains region of Jazan Province, southern portion of Makkah Province, and limited areas in the northern regions of Madinah Province. The annual AET ranged from 418.8 to 3442.3 mm yr-1. The normal distribution of mean annual AET values ranged from 717 to 1020 mm yr-1. Forty-two percent of the study area had an annual AET that ranged from 717 to 1020 mm yr-1. The second highest range of frequencies was concentrated around 1020-1322 mm yr-1, representing the majority of agricultural land. The consumptive water use of the different land cover types in study area indicated that irrigated cropland which occupied 14.6% of the study area had AET rates much higher than other land uses. Water bodies are the next highest, with forest and shrubland and sparse vegetation slightly lower, and very low AET rates from bare soil. Daily and seasonal water consumption of major cropping systems varied spatially depending on cropping practices and climatic conditions.

Consequences of 1.5 °C and 2 °C global warming levels for temperature and precipitation changes over Central Africa

NASA Astrophysics Data System (ADS)

Pokam Mba, Wilfried; Longandjo, Georges-Noel T.; Moufouma-Okia, Wilfran; Bell, Jean-Pierre; James, Rachel; Vondou, Derbetini A.; Haensler, Andreas; Fotso-Nguemo, Thierry C.; Merlin Guenang, Guy; Djiotang Tchotchou, Angennes Lucie; Kamsu-Tamo, Pierre H.; Takong, Ridick R.; Nikulin, Grigory; Lennard, Christopher J.; Dosio, Alessandro

2018-05-01

Discriminating climate impacts between 1.5 °C and 2 °C warming levels is particularly important for Central Africa, a vulnerable region where multiple biophysical, political, and socioeconomic stresses interact to constrain the region’s adaptive capacity. This study uses an ensemble of 25 transient Regional Climate Model (RCM) simulations from the CORDEX initiative, forced with the Representative Concentration Pathway (RCP) 8.5, to investigate the potential temperature and precipitation changes in Central Africa corresponding to 1.5 °C and 2 °C global warming levels. Global climate model simulations from the Coupled Model Intercomparison Project phase 5 (CMIP5) are used to drive the RCMs and determine timing of the targeted global warming levels. The regional warming differs over Central Africa between 1.5 °C and 2 °C global warming levels. Whilst there are large uncertainties associated with projections at 1.5 °C and 2 °C, the 0.5 °C increase in global temperature is associated with larger regional warming response. Compared to changes in temperature, changes in precipitation are more heterogeneous and climate model simulations indicate a lack of consensus across the region, though there is a tendency towards decreasing seasonal precipitation in March–May, and a reduction of consecutive wet days. As a drought indicator, a significant increase in consecutive dry days was found. Consistent changes of maximum 5 day rainfall are also detected between 1.5 °C vs. 2 °C global warming levels.

Impacts of regional transport on black carbon in Huairou, Beijing, China.

PubMed

Wang, Yuqin; de Foy, Benjamin; Schauer, James J; Olson, Michael R; Zhang, Yang; Li, Zhengqiang; Zhang, Yuanxun

2017-02-01

The 22 nd Asia-Pacific Economic Cooperation (APEC) Conference was held near Yanqi Lake, Huairou, in Beijing, China during November 10-11, 2014. To guarantee haze-free days during the APEC Conference, the Beijing government and the governments of the surrounding provinces implemented a series of controls. Three months of Aethalometer 880 nm black carbon (BC) measurements were examined to understand the hourly fluctuations in BC concentrations that resulted from emission controls and meteorology changes. Measurements were collected at the University of Chinese Academy of Sciences near the APEC Conference site and in Central Beijing at the Institute of Remote Sensing and Digital Earth of the Chinese Academy of Sciences. Synoptic conditions are successfully represented through analysis of backward trajectories in six cluster groups. The clusters are identified based on air mass transport from various areas such as Inner Mongolia, Russia, three northeastern provinces, and Hebei industrial areas, to the measurement sites. Air pollution control measures during the APEC Conference significantly reduced BC at the conference site (Huairou) and in Central Beijing, with greater reductions in BC concentrations at the conference site than in Central Beijing. The highest BC concentrations in Huairou were associated with air masses originating from Central Beijing rather than from the Hebei industrial region. The success of the control measures implemented in Beijing and the surrounding regions demonstrates that BC concentrations can be effectively reduced to protect human health and mitigate regional climate forcing. This study also demonstrates the need for regional strategies to reduce BC concentrations, since urban areas like Beijing are sources as well as downwind receptors of emissions. Copyright © 2016 Elsevier Ltd. All rights reserved.

T2 values of articular cartilage in clinically relevant subregions of the asymptomatic knee.

PubMed

Surowiec, Rachel K; Lucas, Erin P; Fitzcharles, Eric K; Petre, Benjamin M; Dornan, Grant J; Giphart, J Erik; LaPrade, Robert F; Ho, Charles P

2014-06-01

In order for T2 mapping to become more clinically applicable, reproducible subregions and standardized T2 parameters must be defined. This study sought to: (1) define clinically relevant subregions of knee cartilage using bone landmarks identifiable on both MR images and during arthroscopy and (2) determine healthy T2 values and T2 texture parameters within these subregions. Twenty-five asymptomatic volunteers (age 18-35) were evaluated with a sagittal T2 mapping sequence. Manual segmentation was performed by three raters, and cartilage was divided into twenty-one subregions modified from the International Cartilage Repair Society Articular Cartilage Mapping System. Mean T2 values and texture parameters (entropy, variance, contrast, homogeneity) were recorded for each subregion, and inter-rater and intra-rater reliability was assessed. The central regions of the condyles had significantly higher T2 values than the posterior regions (P < 0.05) and higher variance than the posterior region on the medial side (P < 0.001). The central trochlea had significantly greater T2 values than the anterior and posterior condyles. The central lateral plateau had lower T2 values, lower variance, higher homogeneity, and lower contrast than nearly all subregions in the tibia. The central patellar regions had higher entropy than the superior and inferior regions (each P ≤ 0.001). Repeatability was good to excellent for all subregions. Significant differences in mean T2 values and texture parameters were found between subregions in this carefully selected asymptomatic population, which suggest that there is normal variation of T2 values within the knee joint. The clinically relevant subregions were found to be robust as demonstrated by the overall high repeatability.

Estimation of selected seasonal streamflow statistics representative of 1930-2002 in West Virginia

USGS Publications Warehouse

Wiley, Jeffrey B.; Atkins, John T.

2010-01-01

Regional equations and procedures were developed for estimating seasonal 1-day 10-year, 7-day 10-year, and 30-day 5-year hydrologically based low-flow frequency values for unregulated streams in West Virginia. Regional equations and procedures also were developed for estimating the seasonal U.S. Environmental Protection Agency harmonic-mean flows and the 50-percent flow-duration values. The seasons were defined as winter (January 1-March 31), spring (April 1-June 30), summer (July 1-September 30), and fall (October 1-December 31). Regional equations were developed using ordinary least squares regression using statistics from 117 U.S. Geological Survey continuous streamgage stations as dependent variables and basin characteristics as independent variables. Equations for three regions in West Virginia-North, South-Central, and Eastern Panhandle Regions-were determined. Drainage area, average annual precipitation, and longitude of the basin centroid are significant independent variables in one or more of the equations. The average standard error of estimates for the equations ranged from 12.6 to 299 percent. Procedures developed to estimate the selected seasonal streamflow statistics in this study are applicable only to rural, unregulated streams within the boundaries of West Virginia that have independent variables within the limits of the stations used to develop the regional equations: drainage area from 16.3 to 1,516 square miles in the North Region, from 2.78 to 1,619 square miles in the South-Central Region, and from 8.83 to 3,041 square miles in the Eastern Panhandle Region; average annual precipitation from 42.3 to 61.4 inches in the South-Central Region and from 39.8 to 52.9 inches in the Eastern Panhandle Region; and longitude of the basin centroid from 79.618 to 82.023 decimal degrees in the North Region. All estimates of seasonal streamflow statistics are representative of the period from the 1930 to the 2002 climatic year.

Estimating the Global Incidence of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review for Central Nervous System Vascular Lesions and Meta-Analysis of Ruptured Aneurysms.

PubMed

Hughes, Joshua D; Bond, Kamila M; Mekary, Rania A; Dewan, Michael C; Rattani, Abbas; Baticulon, Ronnie; Kato, Yoko; Azevedo-Filho, Hildo; Morcos, Jacques J; Park, Kee B

2018-04-09

There is increasing acknowledgement that surgical care is important in global health initiatives. In particular, neurosurgical care is as limited as 1 per 10 million people in parts of the world. We performed a systematic literature review to examine the worldwide incidence of central nervous system vascular lesions and a meta-analysis of aneurysmal subarachnoid hemorrhage (aSAH) to define the disease burden and inform neurosurgical global health efforts. A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to estimate the global epidemiology of central nervous system vascular lesions, including unruptured and ruptured aneurysms, arteriovenous malformations, cavernous malformations, dural arteriovenous fistulas, developmental venous anomalies, and vein of Galen malformations. Results were organized by World Health Organization regions. After literature review, because of a lack of data from particular World Health Organization regions, we determined we could only provide an estimate of aSAH. Using data from studies with aSAH and 12 high-quality stroke studies from regions lacking data, we meta-analyzed the yearly crude incidence of aSAH per 100,000 persons. Estimates were generated via random-effects models. From an initial yield of 1492 studies, 46 manuscripts on aSAH incidence were included. The final meta-analysis included 58 studies from 31 different countries. We estimated the global crude incidence for aSAH to be 6.67 per 100,000 persons with a wide variation across WHO regions from 0.71 to 12.38 per 100,000 persons. Worldwide, almost 500,000 individuals will suffer from aSAH each year, with almost two-thirds in low- and middle-income countries. Copyright © 2018 Elsevier Inc. All rights reserved.

Genotype identification of human cystic echinococcosis in Isfahan, central Iran.

PubMed

Kia, Eshrat Bigom; Rahimi, Hamidreza; Sharbatkhori, Mitra; Talebi, Ardeshir; Fasihi Harandi, Majid; Mirhendi, Hossein

2010-08-01

Echinococcosis/hydatidosis is one of the most important zoonotic diseases commonly found in different regions of Iran with a major economic and public health importance. In the current study, Echinococcus granulosus isolates were collected from hospitalized patients in Isfahan, central Iran. The genotypes of 30 samples were determined by polymerase chain reaction amplification of internal transcribed spacer-1 region of ribosomal DNA, followed by restriction fragment length polymorphism (RFLP) with two restriction enzymes namely AluI and MspI. As expected, each isolate yielded an approximately 1-kbp DNA fragment on the electrophoresis gel. According to RFLP results for both enzymes, all isolates had an equal pattern indicating the G1 genotype. Our findings confirmed that G1 is the dominant genotype of cystic echinococcosis in human in central Iran, with predilection to different organs including liver, lung, and brain, and warrants the importance of sheep dog cycle in public health.

Early evolution of salt structures in north Louisiana salt basin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lobao, J.J.; Pilger, R.H. Jr.

1986-05-01

Several salt diapirs and pillows in southern and central north Louisiana have been studied using approximately 355 mi (570 km) of seismic reflection data and information from 57 deep well holes. Using seismic profiles with deep well-hole data is the most advantageous method to document regional salt tectonism through time. The following conclusions were reached on diapirism in the North Louisiana Salt basin. (1) The diapiric event began early (early Coahuilan) in the southern and central part of the basin, and later (late Coahuilan to Comanchean) in the northern part. (2) The initial diapiric event is much more abrupt andmore » intense in the southern and central diapirs when compared with the later diapiric event in the northern diapirs. (3) Regional depocenter shifting, relative sea level, local erosion with salt extrusion, and rapid depositional loading of sediments are the major controls on diapirism in the basin.« less

AmeriFlux US-MOz Missouri Ozark Site

DOE Data Explorer

Gu, Lianhong [Oak Ridge National Laboratory

2016-01-01

This is the AmeriFlux version of the carbon flux data for the site US-MOz Missouri Ozark Site. Site Description - The site is located in the University of Missouri Baskett Wildlife Research area, situated in the Ozark region of central Missouri. The site is uniquely located in the ecologically important transitional zone between the central hardwood region and the central grassland region of the US. The land has been publically owned since the 1930s, and is on a land tract that was forested with the same dominant species before settlement in the early 1800s.

Gender Role Attitudes among Higher Education Students in a Borderland Central-Eastern European Region Called "Partium"

ERIC Educational Resources Information Center

Fényes, Hajnalka

2014-01-01

In this paper, we examine the attitudes towards gender roles among higher education students in a borderland Central-Eastern European region. We used the database of "The Impact of Tertiary Education on Regional Development" project (N = 602, 2010). We intend to determine what kind of attitudes towards gender roles the students identify…

A Year of Transition: North Central Regional Center for Rural Development Annual Report 2009

ERIC Educational Resources Information Center

North Central Regional Center for Rural Development, 2009

2009-01-01

The North Central Regional Center for Rural Development (NCRCRD) is one of four centers in the United States that work to improve opportunities and quality of life in rural communities. With funding from the USDA National Institute of Food and Agriculture and the land-grant universities in its 12-state region, the NCRCRD engages Extension…

Ethnobotanical study of medicinal plants used in the management of diabetes mellitus and hypertension in the Central Region of Togo.

PubMed

Karou, Simplice Damintoti; Tchacondo, Tchadjobo; Djikpo Tchibozo, Micheline Agassounon; Abdoul-Rahaman, Saliou; Anani, Kokou; Koudouvo, Koffi; Batawila, Komlan; Agbonon, Amegnona; Simpore, Jacques; de Souza, Comlan

2011-12-01

The Tem tribe in the Central Region of Togo is a population with an extensive knowledge of medicinal plants. However, little is known about their medical practices, principally the use of plants in the management of diabetes mellitus (DM) and hypertension (HTN). The present study documented the indigenous medicinal plant utilization for the management of DM and HTN in the Togo Central Region. From March to October 2010, 55 traditional healers were interviewed about their knowledge on the use of plants for DM and HTN treatment. The results revealed that 35/55 (63.64%) healers had treated at least one case of DM and/or HTN. They highlighted the use of 64 species belonging to 31 families in the treatment of DM and/or HTN. The most used plants against diabetes were Psidium guajava L. (Myrtaceae), Khaya senegalensis A. Juss. (Meliaceae), Sarcocephalus latifolius (Sm.) E.A. Bruce (Rubiaceae), Annona muricata L. (Annonaceae), Bridelia ferruginea Benth. (Phyllanthaceae), and Securidaca longepedunculata Fresen. (Polygalacae), while Allium sativum L. (Liliaceae) and Parkia biglobosa Benth. (Fabaceae), followed by Khaya senegalensis A. Juss. (Meliaceae), Gardenia ternifolia Schumach. (Rubiaceae), and Persea americana Mill. (Lauraceae) were the most commonly cited as antihypertensive. The issue revealed that traditional healers of the above mentioned region have basic knowledge regarding herbal medicine for DM and HTN in comparison with previous published reports. Further pharmacological screening of the identified plants should be conducted to ascertain the effectiveness of these plants.

Inter-hemispheric functional connectivity disruption in children with prenatal alcohol exposure

PubMed Central

Wozniak, Jeffrey R.; Mueller, Bryon A.; Muetzel, Ryan L.; Bell, Christopher J.; Hoecker, Heather L.; Nelson, Miranda L.; Chang, Pi-Nian; Lim, Kelvin O.

2010-01-01

Background MRI studies, including recent diffusion tensor imaging (DTI) studies, have shown corpus callosum abnormalities in children prenatally exposed to alcohol, especially in the posterior regions. These abnormalities appear across the range of Fetal Alcohol Spectrum Disorders (FASD). Several studies have demonstrated cognitive correlates of callosal abnormalities in FASD including deficits in visual-motor skill, verbal learning, and executive functioning. The goal of this study was to determine if inter-hemispheric structural connectivity abnormalities in FASD are associated with disrupted inter-hemispheric functional connectivity and disrupted cognition. Methods Twenty-one children with FASD and 23 matched controls underwent a six minute resting-state functional MRI scan as well as anatomical imaging and DTI. Using a semiautomated method, we parsed the corpus callosum and delineated seven inter-hemispheric white matter tracts with DTI tractography. Cortical regions of interest (ROIs) at the distal ends of these tracts were identified. Right-left correlations in resting fMRI signal were computed for these sets of ROIs and group comparisons were done. Correlations with facial dysmorphology, cognition, and DTI measures were computed. Results A significant group difference in inter-hemispheric functional connectivity was seen in a posterior set of ROIs, the para-central region. Children with FASD had functional connectivity that was 12% lower than controls in this region. Sub-group analyses were not possible due to small sample size, but the data suggest that there were effects across the FASD spectrum. No significant association with facial dysmorphology was found. Para-central functional connectivity was significantly correlated with DTI mean diffusivity, a measure of microstructural integrity, in posterior callosal tracts in controls but not in FASD. Significant correlations were seen between these structural and functional measures and Wechsler perceptual reasoning ability. Conclusions Inter-hemispheric functional connectivity disturbances were observed in children with FASD relative to controls. The disruption was measured in medial parietal regions (para-central) that are connected by posterior callosal fiber projections. We have previously shown microstructural abnormalities in these same posterior callosal regions and the current study suggests a possible relationship between the two. These measures have clinical relevance as they are associated with cognitive functioning. PMID:21303384

A Study of Regional Wave Source Time Functions of Central Asian Earthquakes

NASA Astrophysics Data System (ADS)

Xie, J.; Perry, M. R.; Schult, F. R.; Wood, J.

2014-12-01

Despite the extensive use of seismic regional waves in seismic event identification and attenuation tomography, very little is known on how seismic sources radiate energy into these waves. For example, whether regional Lg wave has the same source spectrum as that of the local S has been questioned by Harr et al. and Frenkel et al. three decades ago; many current investigators assume source spectra in Lg, Sn, Pg, Pn and Lg coda waves have either the same or very similar corner frequencies, in contrast to local P and S spectra whose corner frequencies differ. The most complete information on how the finite source ruptures radiate energy into regional waves is contained in the time domain source time functions (STFs). To estimate the STFs of regional waves using the empirical Green's function (EGF) method, we have been substantially modifying a semi-automotive computer procedure to cope with the increasingly diverse and inconsistent naming patterns of new data files from the IRIS DMC. We are applying the modified procedure to many earthquakes in central Asia to study the STFs of various regional waves to see whether they have the same durations and pulse shapes, and how frequently source directivity occur. When applicable, we also examine the differences between STFs of local P and S waves and those of regional waves. The result of these analyses will be presented at the meeting.

Facies Analysis and Depositional environment of the Oligocene-Miocene Qom Formation in the Central Iran (Semnan area)

NASA Astrophysics Data System (ADS)

Sabouhi, Mostafa; Sheykh, Morteza; Darvish, Zohreh; Naghavi Azad, Maral

2010-05-01

The Qom formation was formed in the Oligo-Miocene during the final sea transgression in Central Iran. This Formation in the Central Iran Basin Contains oil and gas. Organic geochemical analysis in previous studies indicated that the hydrocarbons migrated from deeper source rocks, likely of Jurassic age. In the Central Iran Basin, the Qom Formation is 1,200m thick and is abounded by the Oligocene Lower Red Formation and the middle Miocene Upper Red Formation. In previous studies, the Qom Formation was divided into nine members designated from oldest to youngest: a, b, c1 to c4, d, e, and f, of which "e" is 300m thick and constitutes the main reservoir. Our study focused on a Qom Section located in the Arvaneh (Semnan) region of Central Iran that is 498m thick. The lower part of the formation was not deposited, and only the following four members of early Miocene age (Aquitanian-Burdigalian) was identified between the lower and upper Red Formation. The studied section mainly consist of limestone, marl, sandy limestone, sandy marl and argillaceous limestone.According to this study(field and laboratory investigations), 9 carbonate microfacies were recognized which are grouped into four facies associations (microfacies group). These facies associations present platform to basin depositional setting and are nominated as: A (Tidal-flat), B (Lagoon), C (Slope) and D (Open marine). Based on paleoecology and Petrographic analysis, it seems the Qom Formation was deposited in a Carbonate shelf setting. The Qom formation constitutes a regional transgressive-regressive sequence that is bounded by two continental units (Lower and Upper Red Formation).

77 FR 52023 - Meeting of the National Drinking Water Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-28

... from 8:30 a.m. to 5:00 p.m., Central Time, and on October 5, 2012, from 8:30 a.m. to 3:00 p.m., Central Time. ADDRESSES: The meeting will be held at EPA's Chicago Regional Office (EPA Region 5) at the Ralph... the public's input (1:00 p.m.-2:00 p.m., Central Time) at the meeting on October 5, 2012. Oral...

Study of meteorological parameters over the central Himalayan region using balloon-borne sensor

NASA Astrophysics Data System (ADS)

Shrivastava, Rahul; Naja, Manish; Gwal, A. K.

2013-06-01

In the present paper we accumulate the recent advances in atmospheric research by analyzing meteorological data. We have calculated meteorological parameters over the central Himalayan region at Nainital (longitude 79.45□ E, latitude 29.35□N). It is a high altitude place (1951 meters) which is very useful for such type of measurement. We have done our work on meteorological parameters in GVAX (Ganges Valley Aerosol Experiment) project. It was an American-Indo project which was use to capture pre-monsoon to post-monsoon conditions to establish a comprehensive baseline for advancements in the study of the effects of Atmospheric conditions of the Ganges Valley. The Balloon Borne Sounding System (BBSS) technique was also used for in-situ measurements of meteorological parameters.

Convection flow structure in the central polar cap

NASA Astrophysics Data System (ADS)

Bristow, W. A.

2017-12-01

A previous study of spatially averaged flow velocity in the central polar cap [Bristow et al., 2015] observed under steady IMF conditions found that it was extremely rare for the average to exceed 850 m/s (less than 0.2 % of the time). Anecdotally, however it is not uncommon to observe line-of-sight velocities in excess of 100 m/s in the McMurdo radar field of view directly over the magnetic pole. This discrepancy motivated this study, which examines the conditions under which high-velocity flows are observed at latitudes greater than 80° magnetic latitude. It was found that highly structured flows are common in the central polar cap, which leads to the flow within regions to have significant deviation from the average. In addition, the high-speed flow regions are usually directed away from the earth-sun line. No specific set of driving conditions was identified to be associated with high-speed flows. The study did conclude that 1)Polar cap velocities are generally highly structured. 2)Flow patterns typically illustrate narrow channels, vortical flow regions, and propagating features. 3) Persistent waves are a regular occurrence. 3)Features are observed to propagate from day side to night side, and from night side to day side.. 4)Convection often exhibits significant difference between the two hemispheres. And 5)About 10% of the time the velocity somewhere in the cap exceeds 1 Km/s The presentation will conclude with a discussion of the physical reasons for the flow structure. Bristow, W. A., E. Amata, J. Spaleta, and M. F. Marcucci (2015), Observations of the relationship between ionospheric central polar cap and dayside throat convection velocities, and solar wind/IMF driving, J. Geophys. Res. Space Physics, 120, doi:10.1002/2015JA021199.

3D intrathoracic region definition and its application to PET-CT analysis

NASA Astrophysics Data System (ADS)

Cheirsilp, Ronnarit; Bascom, Rebecca; Allen, Thomas W.; Higgins, William E.

2014-03-01

Recently developed integrated PET-CT scanners give co-registered multimodal data sets that offer complementary three-dimensional (3D) digital images of the chest. PET (positron emission tomography) imaging gives highly specific functional information of suspect cancer sites, while CT (X-ray computed tomography) gives associated anatomical detail. Because the 3D CT and PET scans generally span the body from the eyes to the knees, accurate definition of the intrathoracic region is vital for focusing attention to the central-chest region. In this way, diagnostically important regions of interest (ROIs), such as central-chest lymph nodes and cancer nodules, can be more efficiently isolated. We propose a method for automatic segmentation of the intrathoracic region from a given co-registered 3D PET-CT study. Using the 3D CT scan as input, the method begins by finding an initial intrathoracic region boundary for a given 2D CT section. Next, active contour analysis, driven by a cost function depending on local image gradient, gradient-direction, and contour shape features, iteratively estimates the contours spanning the intrathoracic region on neighboring 2D CT sections. This process continues until the complete region is defined. We next present an interactive system that employs the segmentation method for focused 3D PET-CT chest image analysis. A validation study over a series of PET-CT studies reveals that the segmentation method gives a Dice index accuracy of less than 98%. In addition, further results demonstrate the utility of the method for focused 3D PET-CT chest image analysis, ROI definition, and visualization.

Phylogeography and spatial genetic structure of the Southern torrent salamander: Implications for conservation and management

USGS Publications Warehouse

Miller, M.P.; Haig, S.M.; Wagner, R.S.

2006-01-01

The Southern torrent salamander (Rhyacotriton variegatus) was recently found not warranted for listing under the US Endangered Species Act due to lack of information regarding population fragmentation and gene flow. Found in small-order streams associated with late-successional coniferous forests of the US Pacific Northwest, threats to their persistence include disturbance related to timber harvest activities. We conducted a study of genetic diversity throughout this species' range to 1) identify major phylogenetic lineages and phylogeographic barriers and 2) elucidate regional patterns of population genetic and spatial phylogeographic structure. Cytochrome b sequence variation was examined for 189 individuals from 72 localities. We identified 3 major lineages corresponding to nonoverlapping geographic regions: a northern California clade, a central Oregon clade, and a northern Oregon clade. The Yaquina River may be a phylogeographic barrier between the northern Oregon and central Oregon clades, whereas the Smith River in northern California appears to correspond to the discontinuity between the central Oregon and northern California clades. Spatial analyses of genetic variation within regions encompassing major clades indicated that the extent of genetic structure is comparable among regions. We discuss our results in the context of conservation efforts for Southern torrent salamanders. ?? The American Genetic Association. 2006. All rights reserved.

An epidemiological survey of Theileria infections in small ruminants in central China.

PubMed

Li, Youquan; Zhang, Xiao; Liu, Zhijie; Chen, Ze; Yang, Jifei; He, Haining; Guan, Guiquan; Liu, Aihong; Ren, Qiaoyun; Niu, Qingli; Liu, Junlong; Luo, Jianxun; Yin, Hong

2014-02-24

Here, we conducted an epidemiological study in five regions in central China to assess the impact of theileriosis on small ruminants. PCR analysis and microscopic evaluations of blood smears to detect ovine and caprine theileriosis was conducted, in which 256 blood samples and 250 ticks were collected from sheep and goats, and tested for Theileria uilenbergi, T. luwenshuni, and T. ovis. The 18S rRNA gene sequences were deduced from positive samples and used for phylogenetic analysis. The results showed that T. luwenshuni was found most frequently in the five investigated regions and the prevalence of T. luwenshuni was found to be very high by PCR analysis. In contrast, T. uilenbergi and T. ovis infections were not detected in these regions. Phylogenetic tree analysis showed that all of the newly isolated Theileria spp. was in the same clade as T. luwenshuni. Haemaphysalis longicornis, which can transmit T. luwenshuni, was also detected in the sampled sheep and goats in these regions. Our results provide important data to increase the understanding of the epidemiology of ovine and caprine theileriosis, and will aid in the implementation of measures to control theileriosis transmission to small ruminants in central China. Copyright © 2013. Published by Elsevier B.V.

[Effects of submarine topography and water depth on distribution of pelagic fish community in minnan-taiwan bank fishing ground].

PubMed

Fang, Shuimei; Yang, Shengyun; Zhang, Chengmao; Zhu, Jinfu

2002-11-01

According to the fishing record of the light-seine information vessel in Minnan-Taiwan bank ground during 1989 to 1999, the effects of submarine topography and water depth on distribution of pelagic fish community in Minnan-Taiwan bank fishing ground was studied. The results showed that the pelagic fish distributed concentratively, while the submarine topography and water depth varied widely, but in different fishing regions, the distribution of pelagic fishes was uneven. The distribution of fishing yield increased from north to south, and closed up from sides of the bank to south or north in the regions. Pelagic fish distributed mainly in mixed water in the southern Taiwan Strait, and in warm water in the Taiwan Strait. The central fishing grounds were at high salt regions. Close gathering regions of pelagic fish or central fishing ground would be varied with the seasonal variation of mixed water in the southern Taiwan Strait and warm water in the Taiwan Strait. Central fishing ground was not only related to submarine topography and water depth, but also related to wind direction, wind-power and various water systems. In the fishing ground, the gathering depth of pelagic fish was 30-60 m in spring and summer, and 40-80 m in autumn and winter.

Effects of Curriculum and Teacher Professional Development on the Language Proficiency of Elementary English Language Learner Students in the Central Region. Final Report. NCEE 2012-4013

ERIC Educational Resources Information Center

Arens, Sheila A.; Stoker, Ginger; Barker, Jane; Shebby, Susan; Wang, Xin; Cicchinelli, Lou F.; Williams, Jean M.

2012-01-01

This study responds to regional and national needs by examining the impact on students' English language proficiency of a particular set of ELL-specific classroom materials in combination with a specific teacher professional development program. The classroom materials used in this study, entitled On Our Way to English (OWE), were authored by…

Descriptive Statistics and Cluster Analysis for Extreme Rainfall in Java Island

NASA Astrophysics Data System (ADS)

E Komalasari, K.; Pawitan, H.; Faqih, A.

2017-03-01

This study aims to describe regional pattern of extreme rainfall based on maximum daily rainfall for period 1983 to 2012 in Java Island. Descriptive statistics analysis was performed to obtain centralization, variation and distribution of maximum precipitation data. Mean and median are utilized to measure central tendency data while Inter Quartile Range (IQR) and standard deviation are utilized to measure variation of data. In addition, skewness and kurtosis used to obtain shape the distribution of rainfall data. Cluster analysis using squared euclidean distance and ward method is applied to perform regional grouping. Result of this study show that mean (average) of maximum daily rainfall in Java Region during period 1983-2012 is around 80-181mm with median between 75-160mm and standard deviation between 17 to 82. Cluster analysis produces four clusters and show that western area of Java tent to have a higher annual maxima of daily rainfall than northern area, and have more variety of annual maximum value.

Shallow-water zoantharians (Cnidaria, Hexacorallia) from the Central Indo-Pacific

PubMed Central

Reimer, James D.; Poliseno, Angelo; Hoeksema, Bert W.

2014-01-01

Abstract Despite the Central Indo-Pacific (CIP) and the Indonesian Archipelago being a well-known region of coral reef biodiversity, particularly in the ‘Coral Triangle’, little published information is available on its zoantharians (Cnidaria: Hexacorallia: Zoantharia). In order to provide a basis for future research on the Indo-Pacific zoantharian fauna and facilitate comparisons between more well-studied regions such as Japan and the Great Barrier Reef, this report deals with CIP zoantharian specimens in the Naturalis collection in Leiden, the Netherlands; 106 specimens were placed into 24 morpho-species and were supplemented with 88 in situ photographic records from Indonesia, the Philippines, and Papua New Guinea. At least nine morpho-species are likely to be undescribed species, indicating that the region needs more research in order to properly understand zoantharian diversity within the CIP. The Naturalis’ zoantharian specimens are listed by species, as well as all relevant collection information, and in situ images are provided to aid in future studies on zoantharians in the CIP. PMID:25349499

Shallow-water zoantharians (Cnidaria, Hexacorallia) from the Central Indo-Pacific.

PubMed

Reimer, James D; Poliseno, Angelo; Hoeksema, Bert W

2014-01-01

Despite the Central Indo-Pacific (CIP) and the Indonesian Archipelago being a well-known region of coral reef biodiversity, particularly in the 'Coral Triangle', little published information is available on its zoantharians (Cnidaria: Hexacorallia: Zoantharia). In order to provide a basis for future research on the Indo-Pacific zoantharian fauna and facilitate comparisons between more well-studied regions such as Japan and the Great Barrier Reef, this report deals with CIP zoantharian specimens in the Naturalis collection in Leiden, the Netherlands; 106 specimens were placed into 24 morpho-species and were supplemented with 88 in situ photographic records from Indonesia, the Philippines, and Papua New Guinea. At least nine morpho-species are likely to be undescribed species, indicating that the region needs more research in order to properly understand zoantharian diversity within the CIP. The Naturalis' zoantharian specimens are listed by species, as well as all relevant collection information, and in situ images are provided to aid in future studies on zoantharians in the CIP.

Development of a transition pathway model using three traditional variables to describe the main structural characteristics of a forest stand type, size, and density

Treesearch

Chad Larson

2006-01-01

The Central Hardwood Region is a unique forest region in the United States, encompassing 340 million acres of land, of which 100 million acres are forested (Parker 1993). The region contains one-fourth of the U.S. population, with approximately 90 percent of the land in private ownership (Parker 1993). In general, private forested lands in the Central Hardwood Region...

Anderson localized modes in a disordered glass optical fiber

NASA Astrophysics Data System (ADS)

Karbasi, Salman; Hosseini, Seyedrasoul; Koch, Karl W.; Hawkins, Thomas; Ballato, John; Mafi, Arash

2014-02-01

A beam of light can propagate in a time-invariant transversely disordered waveguide because of transverse Anderson localization. We developed a disordered glass optical ber from a porous artisan glass (satin quartz). The refractive index pro le of the disordered glass optical ber is composed of a non-uniform distribution of air voids which can be approximated as longitudinally invariant. The ll-fraction of air voids is higher at the regions closer to the boundary compared with the central regions. The experimental results show that the beam radius of a localized beam is smaller at the regions closer to the boundary than the one at the central regions. In order to understand the reason behind these observations, the fully vectorial modes of the disordered glass ber are calculated using the actual scanning electron microscope image of the ber tip. The numerical calculations show that the modes at regions closer to the boundary of the ber are more localized compared with the modes at the central regions. Coupling of an input beam to the less-localized modes with large tails at the central regions of the ber results in a large beam radius. In comparison, a beam of light launched at the regions close to the boundary couples to the highly compact modes of the ber and results in a small localized beam radius.

49 CFR 190.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Offices are located in Trenton, NJ (Eastern Region); Atlanta, Georgia (Southern Region); Kansas City, Missouri (Central Region); Houston, Texas (Southwest Region); and Lakewood, Colorado (Western Region...

Landsat-based trend analysis of lake dynamics across northern permafrost regions

USGS Publications Warehouse

Nitze, Ingmar; Grosse, Guido; Jones, Benjamin M.; Arp, Christopher D.; Ulrich, Mathias; Federov, Alexander; Veremeeva, Alexandra

2017-01-01

Lakes are a ubiquitous landscape feature in northern permafrost regions. They have a strong impact on carbon, energy and water fluxes and can be quite responsive to climate change. The monitoring of lake change in northern high latitudes, at a sufficiently accurate spatial and temporal resolution, is crucial for understanding the underlying processes driving lake change. To date, lake change studies in permafrost regions were based on a variety of different sources, image acquisition periods and single snapshots, and localized analysis, which hinders the comparison of different regions. Here we present, a methodology based on machine-learning based classification of robust trends of multi-spectral indices of Landsat data (TM,ETM+, OLI) and object-based lake detection, to analyze and compare the individual, local and regional lake dynamics of four different study sites (Alaska North Slope, Western Alaska, Central Yakutia, Kolyma Lowland) in the northern permafrost zone from 1999 to 2014. Regional patterns of lake area change on the Alaska North Slope (-0.69%), Western Alaska (-2.82%), and Kolyma Lowland (-0.51%) largely include increases due to thermokarst lake expansion, but more dominant lake area losses due to catastrophic lake drainage events. In contrast, Central Yakutia showed a remarkable increase in lake area of 48.48%, likely resulting from warmer and wetter climate conditions over the latter half of the study period. Within all study regions, variability in lake dynamics was associated with differences in permafrost characteristics, landscape position (i.e. upland vs. lowland), and surface geology. With the global availability of Landsat data and a consistent methodology for processing the input data derived from robust trends of multi-spectral indices, we demonstrate a transferability, scalability and consistency of lake change analysis within the northern permafrost region.

Impact of climate change on the streamflow hydrology of the Yangtze River in China

USDA-ARS?s Scientific Manuscript database

Tuotuo River basin, the source region of the Yangtze River, is the key area, where the impact of climate change has been observed on many of the hydrological processes of this central region of the Tibetan Plateau. In this study, we examined six global climate models (GCMs) under three Respectively ...

A Nubian Complex Site from Central Arabia: Implications for Levallois Taxonomy and Human Dispersals during the Upper Pleistocene

PubMed Central

Crassard, Rémy; Hilbert, Yamandú Hieronymus

2013-01-01

Archaeological survey undertaken in central Saudi Arabia has revealed 29 surface sites attributed to the Arabian Middle Paleolithic based on the presence of Levallois blank production methods. Technological analyses on cores retrieved from Al-Kharj 22 have revealed specific reduction modalities used to produce flakes with predetermined shapes. The identified modalities, which are anchored within the greater Levallois concept of core convexity preparation and exploitation, correspond with those utilized during the Middle Stone Age Nubian Complex of northeast Africa and southern Arabia. The discovery of Nubian technology at the Al-Kharj 22 site represents the first appearance of this blank production method in central Arabia. Here we demonstrate how a rigorous use of technological and taxonomic analysis may enable intra-regional comparisons across the Arabian Peninsula. The discovery of Al-Kharj 22 increases the complexity of the Arabian Middle Paleolithic archaeological record and suggests new dynamics of population movements between the southern and central regions of the Peninsula. This study also addresses the dichotomy within Nubian core typology (Types 1 and 2), which was originally defined for African assemblages. PMID:23894434

[Centralization in obstetrics: pros and cons].

PubMed

Roemer, V M; Ramb, S

1996-01-01

Possible advantages and disadvantages of a general centralization of German obstetric facilities are analysed in the study. The need for centralization of risk cases, especially premature births (regionalization) is pointed out. Centralization appears appropriate, since every fifth maternity unit in Germany (19.78%) has 300 or fewer deliveries per year. This one fifth of perinatal clinics accounts for 6.3% of all deliveries (N = 49450). There are appreciable differences between the old and new federal states (Bundesländer): in the recently acceded federal states, 48.7% of all perinatal clinics have deliveries of 300 and less per year. This group of perinatal clinics accounts for 29% of all deliveries in the new federal states. We have carried out a survey of the mother's attitude to centralization: out of 416 patients in the Detmold women's hospital whose mean age was 29.0 +/- 4.2 years, 90.4% were not in favor of general centralization of obstetrics. 43% were also against a centralization of risk cases (regionalization). 75% of the women surveyed objected to centralized obstetrics because of the 'possible absence of the family', the 'possible absence of students and trainees' (44.9%), the 'unfamiliarity with staff and premises' (41.8%) and 'fear of anonymity' (44.5%). The majority of all women (84.1%) did not want to have a drive more than 20 km to an obstetrics center. Fear of 'delivery in a taxi'(78.6%), the 'fear that the husband will come too late to the delivery' (65.4%) and that the 'overall course of the delivery might not be adequate for reasons of time'. The presence of a pediatrics department in conjunction with the perinatal clinic was rated very positively (93%). It is concluded from the data and further juridical considerations that centralization of risk cases (regionalization) is indispensable in the near future and that somewhat more further into the future decentralization should be carried out by closing obstetrics departments with substantially less than 350 deliveries per year. Attention is drawn to some consequences of such a structural reform which will probably have to be initiated by the German Association of Gynecologists and Obstetricians.

Optimal and centralized reservoir management for drought and flood protection via Stochastic Dual Dynamic Programming on the Upper Seine-Aube River system

NASA Astrophysics Data System (ADS)

Chiavico, Mattia; Raso, Luciano; Dorchies, David; Malaterre, Pierre-Olivier

2015-04-01

Seine river region is an extremely important logistic and economic junction for France and Europe. The hydraulic protection of most part of the region relies on four controlled reservoirs, managed by EPTB Seine-Grands Lacs. Presently, reservoirs operation is not centrally coordinated, and release rules are based on empirical filling curves. In this study, we analyze how a centralized release policy can face flood and drought risks, optimizing water system efficiency. The optimal and centralized decisional problem is solved by Stochastic Dual Dynamic Programming (SDDP) method, minimizing an operational indicator for each planning objective. SDDP allows us to include into the system: 1) the hydrological discharge, specifically a stochastic semi-distributed auto-regressive model, 2) the hydraulic transfer model, represented by a linear lag and route model, and 3) reservoirs and diversions. The novelty of this study lies on the combination of reservoir and hydraulic models in SDDP for flood and drought protection problems. The study case covers the Seine basin until the confluence with Aube River: this system includes two reservoirs, the city of Troyes, and the Nuclear power plant of Nogent-Sur-Seine. The conflict between the interests of flood protection, drought protection, water use and ecology leads to analyze the environmental system in a Multi-Objective perspective.

Medicinal plants use in central Togo (Africa) with an emphasis on the timing

PubMed Central

Tchacondo, Tchadjobo; Karou, Simplice D.; Agban, Amégninou; Bako, Mamouda; Batawila, Komlan; Bawa, Moctar L.; Gbeassor, Mensavi; de Souza, Comlan

2012-01-01

Background: Plant-based remedies continue to play a key role in the health care of people in Togo; however, there is a lack of published data in medicinal plants and medical practices of the people in the country. Objective: This study was aimed at documenting the plant utilization in the Tem folk medicine in the central region of Togo. Materials and Methods: An ethnobotanical survey was conducted with traditional healers in the central region of Togo using a semi-structured questionnaire. Results: This study demonstrated that local specialists in the central region of Togo tend to agree with each other in terms of the plants used to treat diabetes (ICF = 0.38), infertility, and abdominal pains (ICF = 0.33), but cite a much more diverse groups of plants to treat problems related to arterial hypertension, sickle cell disease, and abscess. They use 144 herbal concoctions made of 72 plants, distributed among 36 botanical families. The Euphorbiaceae family with eight species was best represented in terms of the number of species. The species with the highest use value were Khaya senegalensis (Desr.) A. Juss. (Meliaceae) (UV = 0.36), Anthocleista djalonensis A. Chev. (Gentianaceae) (UV = 0.27), Trichilia emetica Vahl (Meliaceae) (UV = 0.25), and Sarcocephalus latifolius (Sm.) E. A. Bruce (Rubiaceae) (UV = 0.21). They also rely on the timing in the plant processing and the administration of herbal remedies. Conclusion: All these findings are based on empirical observations; laboratory screenings are needed to check the effectiveness of these plants. PMID:22518081

D″ shear velocity heterogeneity, anisotropy and discontinuity structure beneath the Caribbean and Central America

NASA Astrophysics Data System (ADS)

Garnero, Edward J.; Lay, Thorne

2003-11-01

The D″ region in the lowermost mantle beneath the Caribbean and Central America is investigated using shear waves from South American earthquakes recorded by seismic stations in North America. We present a large-scale, composite study of volumetric shear velocity heterogeneity, anisotropy, and the possible presence of a D″ discontinuity in the region. Our data set includes: 328 S( Sdiff)- SKS differential travel times, 300 ScS-S differential travel times, 125 S( Sdiff) and 120 ScS shear wave splitting measurements, and 297 seismograms inspected for Scd, the seismic phase refracted from a high-velocity D″ layer. Broadband digital data are augmented by high-quality digitized analog WWSSN data, providing extensive path coverage in our study area. In all, data from 61 events are utilized. In some cases, a given seismogram can be used for velocity heterogeneity, anisotropy, and discontinuity analyses. Significant mid-mantle structure, possibly associated with the ancient subducted Farallon slab, affects shear wave travel times and must be corrected for to prevent erroneous mapping of D″ shear velocity. All differential times are corrected for contributions from aspherical mantle structure above D″ using a high-resolution tomography model. Travel time analyses demonstrate the presence of pervasive high velocities in D″, with the highest velocities localized to a region beneath Central America, approximately 500-700 km in lateral dimension. Short wavelength variability overprints this general high-velocity background. Corrections are also made for lithospheric anisotropy beneath the receivers. Shear wave splitting analyses of the corrected waveforms reveal D″ anisotropy throughout the study area, with a general correlation with heterogeneity strength. Evidence for Scd arrivals is pervasive across the study area, consistent with earlier work, but there are a few localized regions (100-200 km) lacking clear Scd arrivals, which indicates heterogeneity in the thickness or velocity gradients of the high-velocity layer. While small-scale geographic patterns of heterogeneity, anisotropy, and discontinuity are present, the details appear complex, and require higher resolution array analyses to fully characterize the structure. Explanations for the high-shear wave speeds, anisotropy, and reflector associated with D″ beneath the Caribbean and Central America must be applicable over a lateral scale of roughly 1500 km 2, the dimension over which we observe coherent wavefield behavior in the region. A slab graveyard appears viable in this regard.

Differential central projections of vestibular afferents in pigeons

NASA Technical Reports Server (NTRS)

Dickman, J. D.; Fang, Q.

1996-01-01

The question of whether a differential distribution of vestibular afferent information to central nuclear neurons is present in pigeons was studied using neural tracer compounds. Discrete tracing of afferent fibers innervating the individual semicircular canal and otolith organs was produced by sectioning individual branches of the vestibular nerve that innervate the different receptor organs and applying crystals of horseradish peroxidase, or a horseradish peroxidase/cholera toxin mixture, or a biocytin compound for neuronal uptake and transport. Afferent fibers and their terminal distributions within the brainstem and cerebellum were visualized subsequently. Discrete areas in the pigeon central nervous system that receive primary vestibular input include the superior, dorsal lateral, ventral lateral, medial, descending, and tangential vestibular nuclei; the A and B groups; the intermediate, medial, and lateral cerebellar nuclei; and the nodulus, the uvula, and the paraflocculus. Generally, the vertical canal afferents projected heavily to medial regions in the superior and descending vestibular nuclei as well as the A group. Vertical canal projections to the medial and lateral vestibular nuclei were observed but were less prominent. Horizontal canal projections to the superior and descending vestibular nuclei were much more centrally located than those of the vertical canals. A more substantial projection to the medial and lateral vestibular nuclei was seen with horizontal canal afferents compared to vertical canal fibers. Afferents innervating the utricle and saccule terminated generally in the lateral regions of all vestibular nuclei in areas that were separate from the projections of the semicircular canals. In addition, utricular fibers projected to regions in the vestibular nuclei that overlapped with the horizontal semicircular canal terminal fields, whereas saccular afferents projected to regions that received vertical canal fiber terminations. Lagenar afferents projected throughout the cochlear nuclei, to the dorsolateral regions of the cerebellar nuclei, and to lateral regions of the superior, lateral, medial, and descending vestibular nuclei.

The impact of hypoglycaemia awareness status on regional brain responses to acute hypoglycaemia in men with type 1 diabetes.

PubMed

Dunn, Joel T; Choudhary, Pratik; Teh, Ming Ming; Macdonald, Ian; Hunt, Katharine F; Marsden, Paul K; Amiel, Stephanie A

2018-05-12

Impaired awareness of hypoglycaemia (IAH) in type 1 diabetes increases the risk of severe hypoglycaemia sixfold and can be resistant to intervention. We explored the impact of IAH on central responses to hypoglycaemia to investigate the mechanisms underlying barriers to therapeutic intervention. We conducted [ 15 O]water positron emission tomography studies of regional brain perfusion during euglycaemia (target 5 mmol/l), hypoglycaemia (achieved level, 2.4 mmol/l) and recovery (target 5 mmol/l) in 17 men with type 1 diabetes: eight with IAH, and nine with intact hypoglycaemia awareness (HA). Hypoglycaemia with HA was associated with increased activation in brain regions including the thalamus, insula, globus pallidus (GP), anterior cingulate cortex (ACC), orbital cortex, dorsolateral frontal (DLF) cortex, angular gyrus and amygdala; deactivation occurred in the temporal and parahippocampal regions. IAH was associated with reduced catecholamine and symptom responses to hypoglycaemia vs HA (incremental AUC: autonomic scores, 26.2 ± 35.5 vs 422.7 ± 237.1; neuroglycopenic scores, 34.8 ± 88.8 vs 478.9 ± 311.1; both p < 0.002). There were subtle differences (p < 0.005, k ≥ 50 voxels) in brain activation at hypoglycaemia, including early differences in the right central operculum, bilateral medial orbital (MO) cortex, and left posterior DLF cortex, with additional differences in the ACC, right GP and post- and pre-central gyri in established hypoglycaemia, and lack of deactivation in temporal regions in established hypoglycaemia. Differences in activation in the post- and pre-central gyri may be expected in people with reduced subjective responses to hypoglycaemia. Alterations in the activity of regions involved in the drive to eat (operculum), emotional salience (MO cortex), aversion (GP) and recall (temporal) suggest differences in the perceived importance and urgency of responses to hypoglycaemia in IAH compared with HA, which may be key to the persistence of the condition.

West Meets East in Central Asia: Competing Discourses on Secondary Education Reform in the Kyrgyz Republic.

ERIC Educational Resources Information Center

De Young, Alan J.

The Kyrgyz Republic--a remote mountainous region--is one of five former Soviet states in central Asia. This case study begins with a brief overview of the political and economic situation of the Kyrgyz Republic and its relation to aims of Soviet schooling in the 20th century. A critique of the Soviet schooling model by foreign academics before and…

The Integration of International Agricultural Concepts into Agricultural Science Programs in the North Central Region of the United States. Summary of Research 78.

ERIC Educational Resources Information Center

Ibezim, Don O.; McCracken, J. David

A study examined the extent to which international agricultural dimensions were taught in secondary agricultural programs and factors associated with the extent of integration. A systematic sampling technique was used to select a random sample of 332 of the 2,612 secondary agricultural teachers in 12 states of the North Central United States. Of…

Descriptive epidemiology of chronic hepatitis B by using data from a hepatitis registry in Central Greece.

PubMed

Stefos, Aggelos; Gatselis, Nikolaos; Zachou, Kalliopi; Rigopoulou, Eirini; Hadjichristodoulou, Christos; Dalekos, George N

2009-01-01

In Greece, there are few data on the epidemiological characteristics of HBV. Our aim was to study the epidemiological patterns of HBV in Central Greece and identify the possible differences in HBV prevalence (clusters) among areas inside this region using data from the hepatitis registry. The study was performed in Thessaly, one out of the thirteen regions of Greece and covers most of the part of Central Greece. A total of 921 HBV patients were registered in the hepatitis registry during the period 1999-2004 while 303 were randomly selected to be studied further using a detailed questionnaire on several epidemiological factors. 187/303 patients (61.7%) classified as chronic inactive HBV carriers, 78/303 (25.7%) had chronic hepatitis B, 29/303 (9.6%) had HBV-related cirrhosis and 9/303 (3%) HBV-related hepatocellular carcinoma (HCC). The route of HBV transmission was vertical in 103 (34%), sexual in 46 (15.1%) and intrafamilial in 98 (32.4%). Folk remedies were identified as the predisposing risk factor for contracting HBV infection in 38 (12.5%), previous transfusion in 9 (3%) and unknown mode of transmission in 9 patients (3%). Alcohol abuse was the only independent factor (OR: 2.5; p=0.01) associated with the progression to cirrhosis-HCC. There were specific areas (clusters) inside Thessaly region with increased ratio of HBV infection; Vertical and sexual modes of transmission were more prominent in some of these areas. Vertical, intrafamilial and sexual modes of HBV transmission identified as the major routes of HBV infection in our study. We also identified cluster areas of HBV infection in Central Greece. Alcohol abuse is frequent among HBV patients and is acting as an effect modificator risk factor for the development of HBV-related cirrhosis and HCC. Extended population studies in Greece are needed to assess in detail the epidemiological patterns of HBV and evaluate control programmes.

Cucurbit germplasm collections at the North Central Regional Plant Introduction Station

USDA-ARS?s Scientific Manuscript database

The North Central Regional Plant Introduction Station (NCRPIS) in Ames, Iowa, USA is one of four primary Plant Introduction Stations in the National Plant Germplasm System (NPGS), and has responsibility for maintenance, regeneration, characterization, and distribution of the NPGS Cucumis and Cucurbi...

40 CFR 81.143 - Central Virginia Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Virginia Intrastate Air Quality Control Region. 81.143 Section 81.143 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY..., Lynchburg, Martinsville, South Boston. Towns—Blackstone, Farmville, Rocky Mount, South Hill. ...

40 CFR 81.142 - Central Massachusetts Intrastate Air Quality Control Region.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Massachusetts Intrastate Air Quality Control Region. 81.142 Section 81.142 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...: Township—Ashburnham, Ashby, Athol, Auburn, Barre, Berlin, Blackstone, Boylston, Brookfield, Charlton...

High-cost, high-capacity backbone for global brain communication.

PubMed

van den Heuvel, Martijn P; Kahn, René S; Goñi, Joaquín; Sporns, Olaf

2012-07-10

Network studies of human brain structural connectivity have identified a specific set of brain regions that are both highly connected and highly central. Recent analyses have shown that these putative hub regions are mutually and densely interconnected, forming a "rich club" within the human brain. Here we show that the set of pathways linking rich club regions forms a central high-cost, high-capacity backbone for global brain communication. Diffusion tensor imaging (DTI) data of two sets of 40 healthy subjects were used to map structural brain networks. The contributions to network cost and communication capacity of global cortico-cortical connections were assessed through measures of their topology and spatial embedding. Rich club connections were found to be more costly than predicted by their density alone and accounted for 40% of the total communication cost. Furthermore, 69% of all minimally short paths between node pairs were found to travel through the rich club and a large proportion of these communication paths consisted of ordered sequences of edges ("path motifs") that first fed into, then traversed, and finally exited the rich club, while passing through nodes of increasing and then decreasing degree. The prevalence of short paths that follow such ordered degree sequences suggests that neural communication might take advantage of strategies for dynamic routing of information between brain regions, with an important role for a highly central rich club. Taken together, our results show that rich club connections make an important contribution to interregional signal traffic, forming a central high-cost, high-capacity backbone for global brain communication.

Domestication and human demographic history in South America.

PubMed

Perez, S Ivan; Postillone, María Bárbara; Rindel, Diego

2017-05-01

The early groups of hunter-gatherers who peopled South America faced significant ecological changes in their trophic niche for a relatively short period after the initial peopling. In particular, the incorporation of cultigens during the Holocene led to a wider trophic niche and probably to an increased carrying capacity of the environment. Here, we study the relationship between the incorporation of domestic resources during the Holocene and the demographic dynamics of human populations at a regional scale in South America. We employ mitochondrial DNA (mtDNA), radiocarbon data and Bayesian methods to estimate differences in population size, human occupation and explore the demographic changes of human populations in three regions (i.e., South-Central Andes, Northwest, and South Patagonia). We also use archaeological evidence to infer the main diet changes in these regions. The absolute population size during the later Late Holocene was fifteen times larger in the South-Central Andes than in Northwest Patagonia, and two times larger in the latter region than in South Patagonia. The South-Central Andes display the earlier and more abrupt population growth, beginning about 9000 years BP, whereas Northwest Patagonia exhibits a more slow growth, beginning about 7000-7500 years BP. South Patagonia represents a later and slower population increase. In this work we uncovered a well-supported pattern of the demographic change in the populations from South-Central Andes and Patagonia, obtained on the basis of different data and quantitative approaches, which suggests that the incorporation of domestic resources was paramount for the demographic expansion of these populations during the Holocene. © 2017 Wiley Periodicals, Inc.

Genomic Epidemiology Reconstructs the Introduction and Spread of Zika Virus in Central America and Mexico.

PubMed

Thézé, Julien; Li, Tony; du Plessis, Louis; Bouquet, Jerome; Kraemer, Moritz U G; Somasekar, Sneha; Yu, Guixia; de Cesare, Mariateresa; Balmaseda, Angel; Kuan, Guillermina; Harris, Eva; Wu, Chieh-Hsi; Ansari, M Azim; Bowden, Rory; Faria, Nuno R; Yagi, Shigeo; Messenger, Sharon; Brooks, Trevor; Stone, Mars; Bloch, Evan M; Busch, Michael; Muñoz-Medina, José E; González-Bonilla, Cesar R; Wolinsky, Steven; López, Susana; Arias, Carlos F; Bonsall, David; Chiu, Charles Y; Pybus, Oliver G

2018-06-13

The Zika virus (ZIKV) epidemic in the Americas established ZIKV as a major public health threat and uncovered its association with severe diseases, including microcephaly. However, genetic epidemiology in some at-risk regions, particularly Central America and Mexico, remains limited. We report 61 ZIKV genomes from this region, generated using metagenomic sequencing with ZIKV-specific enrichment, and combine phylogenetic, epidemiological, and environmental data to reconstruct ZIKV transmission. These analyses revealed multiple independent ZIKV introductions to Central America and Mexico. One introduction, likely from Brazil via Honduras, led to most infections and the undetected spread of ZIKV through the region from late 2014. Multiple lines of evidence indicate biannual peaks of ZIKV transmission in the region, likely driven by varying local environmental conditions for mosquito vectors and herd immunity. The spatial and temporal heterogeneity of ZIKV transmission in Central America and Mexico challenges arbovirus surveillance and disease control measures. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Photoionization Models of the H_2 Emission of the Narrow Line Region of AGNs

NASA Astrophysics Data System (ADS)

Aleman, I.; Gruenwald, R.

2011-05-01

The excitation mechanism of the narrow line region (NLR) of AGNs is still an open question. Excitation by UV radiation from O and B stars, x-rays from the central black hole, shock from supernovae or jets, or a combination of these mechanisms have been suggested. In the present work, we use photoionization models to study the excitation mechanisms of the H_2 infrared emission lines in the NLR. In the literature, analyzes of the H_2 emission have been done assuming that the molecules is present only in neutral regions (photodissociation regions, x-ray-dominated regions, or shocks; Veilleux et al. 1997, Krabbe et al. 2000, Rigopoulou et al. 2002, Rodriguez-Ardila et al. 2004, 2005, and Davies et al. 2005). However, they are not conclusive. In previous work (Aleman & Gruenwald 2004, 2011), we show that the H_2 emission from the ionized region of PNe can be significant for planetary nebulae (PNe) with hot central stars (T⋆ > 150000 K). Such stars produce copious amounts of high energy photons, which create an extended partially ionized region that favors the H_2 survival. The conditions in the NLR are similar to those in PNe with hot central stars, so we can expect that the H_2 emission might also be important. We obtain and analyze a grid of photoionization models for different NRL parameters. We study the resulting H_2 density and emission, as well as, the formation, destruction, excitation, and de-excitation mechanisms. The higher values observed for the H_2 1-0 S(1)/Brγ ratio cannot be reproduced by our models. The calculated ratios are between 10^-8 and 10^-1, while the observational ration can be as high as 10. The calculated ratio is strongly anti-correlated with the ionization parameter (U) and only models with U<10-3 result in ratios inside the observational range. We show that the NLR is an environment more hostile to the H_2 molecule than the ionized region of PNe. Another interesting result of our calculations is that the H_2 formation on grain surfaces is more important in the NLR than in the ionized region of PNe.

Are visual peripheries forever young?

PubMed

Burnat, Kalina

2015-01-01

The paper presents a concept of lifelong plasticity of peripheral vision. Central vision processing is accepted as critical and irreplaceable for normal perception in humans. While peripheral processing chiefly carries information about motion stimuli features and redirects foveal attention to new objects, it can also take over functions typical for central vision. Here I review the data showing the plasticity of peripheral vision found in functional, developmental, and comparative studies. Even though it is well established that afferent projections from central and peripheral retinal regions are not established simultaneously during early postnatal life, central vision is commonly used as a general model of development of the visual system. Based on clinical studies and visually deprived animal models, I describe how central and peripheral visual field representations separately rely on early visual experience. Peripheral visual processing (motion) is more affected by binocular visual deprivation than central visual processing (spatial resolution). In addition, our own experimental findings show the possible recruitment of coarse peripheral vision for fine spatial analysis. Accordingly, I hypothesize that the balance between central and peripheral visual processing, established in the course of development, is susceptible to plastic adaptations during the entire life span, with peripheral vision capable of taking over central processing.

India Should Develop Its Naval Power in View of Growing Potential Security Concerns Connected to China’s Non-Transparent Intentions in the Indian Ocean Region

DTIC Science & Technology

2017-06-09

across the Indian Ocean is central to interests of India and China. Hence, both have increased their regional presence using diplomatic, economic , and...trade across the Indian Ocean is central to interests of India and China. Hence, both have increased their regional presence using diplomatic, economic ...of Defense Staff CPEC China Pakistan Economic Corridor GDP Gross Domestic Product IOR Indian Ocean Region NSS National Security Strategy PLAN

Experience-dependent central vision deficits: Neurobiology and visual acuity.

PubMed

Williams, Kate; Balsor, Justin L; Beshara, Simon; Beston, Brett R; Jones, David G; Murphy, Kathryn M

2015-09-01

Abnormal visual experience during childhood often leads to amblyopia, with strong links to binocular dysfunction that can include poor acuity in both eyes, especially in central vision. In animal models of amblyopia, the non-deprived eye is often considered normal and what limits binocular acuity. This leaves open the question whether monocular deprivation (MD) induces binocular dysfunction similar to what is found in amblyopia. In previous studies of MD cats, we found a loss of excitatory receptors restricted to the central visual field representation in visual cortex (V1), including both eyes' columns. This led us to ask two questions about the effects of MD: how quickly are receptors lost in V1? and is there an impact on binocular acuity? We found that just a few hours of MD caused a rapid loss of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor proteins across all of V1. But after a few days of MD, there was recovery in the visual periphery, leaving a loss of AMPA receptors only in the central region of V1. We reared animals with early MD followed by a long period of binocular vision and found binocular acuity deficits that were greatest in the central visual field. Our results suggest that the greater binocular acuity deficits in the central visual field are driven in part by the long-term loss of AMPA receptors in the central region of V1. Copyright © 2014 Elsevier Ltd. All rights reserved.

A study of Quaternary structures in the Qom region, West Central Iran

NASA Astrophysics Data System (ADS)

Babaahmadi, A.; Safaei, H.; Yassaghi, A.; Vafa, H.; Naeimi, A.; Madanipour, S.; Ahmadi, M.

2010-12-01

West Central Iran comprises numerous Quaternary faults. Having either strike-slip or thrust mechanisms, these faults are potentially active and therefore capable of creating destructive earthquakes. In this paper, we use satellite images as well as field trips to identify these active faults in the Qom region. The Qom and Indes faults are the main NW-trending faults along which a Quaternary restraining step-over zone has formed. Kamarkuh, Mohsen Abad, and Ferdows anticlines are potentially active structures that formed in this restraining step-over zone. There are some thrusts and anticlines, such as the Alborz anticline and Alborz fault, which are parallel to strike-slip faults such as the Qom fault, indicating deformation partitioning in the area. In addition to NW-trending structures, there is an important NE-trending fault known as the Qomrud fault that has deformed Quaternary deposits and affected Kushk-e-Nosrat fault, Alborz anticline, and Qomrud River. The results of this study imply that the major Quaternary faults of West Central Iran and their restraining step-over zones are potentially active.

Maternal Genetic Composition of a Medieval Population from a Hungarian-Slavic Contact Zone in Central Europe.

PubMed

Csákyová, Veronika; Szécsényi-Nagy, Anna; Csősz, Aranka; Nagy, Melinda; Fusek, Gabriel; Langó, Péter; Bauer, Miroslav; Mende, Balázs Gusztáv; Makovický, Pavol; Bauerová, Mária

2016-01-01

The genetic composition of the medieval populations of Central Europe has been poorly investigated to date. In particular, the region of modern-day Slovakia is a blank spot in archaeogenetic research. This paper reports the study of mitochondrial DNA (mtDNA) in ancient samples from the 9th-12th centuries originating from the cemeteries discovered in Nitra-Šindolka and Čakajovce, located in western Slovakia (Central Europe). This geographical region is interesting to study because its medieval multi-ethnic population lived in the so-called contact zone of the territory of the Great Moravian and later Hungarian state formations. We described 16 different mtDNA haplotypes in 19 individuals, which belong to the most widespread European mtDNA haplogroups: H, J, T, U and R0. Using comparative statistical and population genetic analyses, we showed the differentiation of the European gene pool in the medieval period. We also demonstrated the heterogeneous genetic characteristics of the investigated population and its affinity to the populations of modern Europe.

Maternal Genetic Composition of a Medieval Population from a Hungarian-Slavic Contact Zone in Central Europe

PubMed Central

Csákyová, Veronika; Szécsényi-Nagy, Anna; Csősz, Aranka; Nagy, Melinda; Fusek, Gabriel; Langó, Péter; Bauer, Miroslav; Mende, Balázs Gusztáv; Makovický, Pavol; Bauerová, Mária

2016-01-01

The genetic composition of the medieval populations of Central Europe has been poorly investigated to date. In particular, the region of modern-day Slovakia is a blank spot in archaeogenetic research. This paper reports the study of mitochondrial DNA (mtDNA) in ancient samples from the 9th–12th centuries originating from the cemeteries discovered in Nitra-Šindolka and Čakajovce, located in western Slovakia (Central Europe). This geographical region is interesting to study because its medieval multi-ethnic population lived in the so-called contact zone of the territory of the Great Moravian and later Hungarian state formations. We described 16 different mtDNA haplotypes in 19 individuals, which belong to the most widespread European mtDNA haplogroups: H, J, T, U and R0. Using comparative statistical and population genetic analyses, we showed the differentiation of the European gene pool in the medieval period. We also demonstrated the heterogeneous genetic characteristics of the investigated population and its affinity to the populations of modern Europe. PMID:26963389

Mapping Multiplex Hubs in Human Functional Brain Networks

PubMed Central

De Domenico, Manlio; Sasai, Shuntaro; Arenas, Alex

2016-01-01

Typical brain networks consist of many peripheral regions and a few highly central ones, i.e., hubs, playing key functional roles in cerebral inter-regional interactions. Studies have shown that networks, obtained from the analysis of specific frequency components of brain activity, present peculiar architectures with unique profiles of region centrality. However, the identification of hubs in networks built from different frequency bands simultaneously is still a challenging problem, remaining largely unexplored. Here we identify each frequency component with one layer of a multiplex network and face this challenge by exploiting the recent advances in the analysis of multiplex topologies. First, we show that each frequency band carries unique topological information, fundamental to accurately model brain functional networks. We then demonstrate that hubs in the multiplex network, in general different from those ones obtained after discarding or aggregating the measured signals as usual, provide a more accurate map of brain's most important functional regions, allowing to distinguish between healthy and schizophrenic populations better than conventional network approaches. PMID:27471443

Programmes, resources, and needs of HIV-prevention nongovernmental organizations (NGOs) in Africa, Central/Eastern Europe and Central Asia, Latin America and the Caribbean.

PubMed

Kelly, J A; Somlai, A M; Benotsch, E G; Amirkhanian, Y A; Fernandez, M I; Stevenson, L Y; Sitzler, C A; McAuliffe, T L; Brown, K D; Opgenorth, K M

2006-01-01

This study assessed the programmes, resources, and needs of HIV-prevention nongovernmental organizations (NGOs) in 75 countries in Africa, Central/Eastern Europe and Central Asia, Latin America and the Caribbean. Multiple databases and expert recommendations were used to identify one major HIV-prevention NGO in the capital or a large city in each country, and in-depth interviews were conducted with each NGO Director. Most NGOs are carrying out their programmes with minimal funding and few regularly employed personnel. Most are highly dependent on international donors, but reliance on small grants with short funding periods limits programme development capacity. HIV-prevention activities varied by region, with African NGOs most likely to use peer education and community awareness events; Eastern European NGOs most likely to offer needle exchange; Latin American NGOs to have resource centres and offer risk reduction programmes; and Caribbean organizations to use mass education approaches. Across regions, NGOs most often targeted the general public and youth, although specialized at-risk groups were the additional focus of attention in some regions. Limited funding, governmental indifference or opposition, AIDS stigma, and social discomfort discussing sex were often cited as barriers to new HIV-prevention programmes. NGOs are critical service providers. However, their funding, programmes, and resource capacities must be strengthened if NGOs are to realize their full potential in HIV prevention.

Programmes, resources, and needs of HIV-prevention nongovernmental organizations (NGOs) in Africa, Central/Eastern Europe and Central Asia, Latin America and the Caribbean

PubMed Central

KELLY, J. A.; SOMLAI, A. M.; BENOTSCH, E. G.; AMIRKHANIAN, Y. A.; FERNANDEZ, M. I.; STEVENSON, L. Y.; SITZLER, C. A.; MCAULIFFE, T. L.; BROWN, K. D.; OPGENORTH, K. M.

2008-01-01

This study assessed the programmes, resources, and needs of HIV-prevention nongovernmental organizations (NGOs) in 75 countries in Africa, Central/Eastern Europe and Central Asia, Latin America and the Caribbean. Multiple databases and expert recommendations were used to identify one major HIV-prevention NGO in the capital or a large city in each country, and in-depth interviews were conducted with each NGO Director. Most NGOs are carrying out their programmes with minimal funding and few regularly employed personnel. Most are highly dependent on international donors, but reliance on small grants with short funding periods limits programme development capacity. HIV-prevention activities varied by region, with African NGOs most likely to use peer education and community awareness events; Eastern European NGOs most likely to offer needle exchange; Latin American NGOs to have resource centres and offer risk reduction programmes; and Caribbean organizations to use mass education approaches. Across regions, NGOs most often targeted the general public and youth, although specialized at-risk groups were the additional focus of attention in some regions. Limited funding, governmental indifference or opposition, AIDS stigma, and social discomfort discussing sex were often cited as barriers to new HIV-prevention programmes. NGOs are critical service providers. However, their funding, programmes, and resource capacities must be strengthened if NGOs are to realize their full potential in HIV prevention. PMID:16282071

Measurement and Analysis of Olfactory Responses with the Aim of Establishing an Objective Diagnostic Method for Central Olfactory Disorders

NASA Astrophysics Data System (ADS)

Uno, Tominori; Wang, Li-Qun; Miwakeichi, Fumikazu; Tonoike, Mitsuo; Kaneda, Teruo

In order to establish a new diagnostic method for central olfactory disorders and to identify objective indicators, we measured and analyzed brain activities in the parahippocampal gyrus and uncus, region of responsibility for central olfactory disorders. The relationship between olfactory stimulation and brain response at region of responsibility can be examined in terms of fitted responses (FR). FR in these regions may be individual indicators of changes in brain olfactory responses. In the present study, in order to non-invasively and objectively measure olfactory responses, an odor oddball task was conducted on four healthy volunteers using functional magnetic resonance imaging (fMRI) and a odorant stimulator with blast-method. The results showed favorable FR and activation in the parahippocampal gyrus or uncus in all subjects. In some subjects, both the parahippocampal gyrus and uncus were activated. Furthermore, activation was also confirmed in the cingulate gyrus, middle frontal gyrus, precentral gyrus, postcentral gyrus, superior temporal gyrus and insula. The hippocampus and uncus are known to be involved in the olfactory disorders associated with early-stage Alzheimer's disease and other olfactory disorders. In the future, it will be necessary to further develop the present measurement and analysis method to clarify the relationship between central olfactory disorders and brain activities and establish objective indicators that are useful for diagnosis.

The newest epidemic: a review of HIV/AIDS in Central and Eastern Europe.

PubMed

Kelly, Jeffrey A; Amirkhanian, Yuri A

2003-06-01

HIV/AIDS has emerged as a grave public health threat in Central and Eastern Europe and in the Central Asian republics over the past five years. Massive political, social, cultural, and behavioural changes - along with economic upheaval and collapse of the public health infrastructure in many countries - have created circumstances conducive to the rapid spread of HIV. This paper reviews HIV and sexually transmitted disease (STD) data for all countries in the region, as well as behavioural, social, cultural, and other HIV epidemic enabling factors. The epidemiological picture of HIV in the region is mixed. Russia, Ukraine, Moldova and Belarus already have advanced epidemics. Some other countries in the region share similar enabling factors and have seen a very high proportion of their total number of HIV infections detected in only the past 18 months, indicating the emergence of recent epidemics. Several countries are more stable in their HIV incidence. Behavioural studies indicate that risky sexual and injection related practices are common in many vulnerable populations. HIV prevention steps, if taken quickly enough and on a large scale, can limit the scope of the HIV epidemic that is now unfolding in Central and Eastern Europe. This will require new models of government/non-governmental organization cooperation, policy approaches for addressing structural factors underlying the epidemic, and attention to human rights protection.

Continuous Morphological Variation Correlated with Genome Size Indicates Frequent Introgressive Hybridization among Diphasiastrum Species (Lycopodiaceae) in Central Europe

PubMed Central

Hanušová, Kristýna; Ekrt, Libor; Vít, Petr; Kolář, Filip; Urfus, Tomáš

2014-01-01

Introgressive hybridization is an important evolutionary process frequently contributing to diversification and speciation of angiosperms. Its extent in other groups of land plants has only rarely been studied, however. We therefore examined the levels of introgression in the genus Diphasiastrum, a taxonomically challenging group of Lycopodiophytes, using flow cytometry and numerical and geometric morphometric analyses. Patterns of morphological and cytological variation were evaluated in an extensive dataset of 561 individuals from 57 populations of six taxa from Central Europe, the region with the largest known taxonomic complexity. In addition, genome size values of 63 individuals from Northern Europe were acquired for comparative purposes. Within Central European populations, we detected a continuous pattern in both morphological variation and genome size (strongly correlated together) suggesting extensive levels of interspecific gene flow within this region, including several large hybrid swarm populations. The secondary character of habitats of Central European hybrid swarm populations suggests that man-made landscape changes might have enhanced unnatural contact of species, resulting in extensive hybridization within this area. On the contrary, a distinct pattern of genome size variation among individuals from other parts of Europe indicates that pure populations prevail outside Central Europe. All in all, introgressive hybridization among Diphasiastrum species in Central Europe represents a unique case of extensive interspecific gene flow among spore producing vascular plants that cause serious complications of taxa delimitation. PMID:24932509

Experiencing Unmet Medical Needs or Delayed Care Because of Cost: Foreign-Born Adults in the U.S. by Region of Birth.

PubMed

Choi, Sunha

2016-10-01

Healthy People 2020 in the United States highlights timely access to necessary health care as a major factor that can reduce health-related disparities. This study examined the prevalence of delaying/missing necessary health care because of cost among foreign-born adults (26+ years old) in the United States by their region of origin, after controlling for geographic clustering at the county and state levels. Using the pooled 2007-2011 National Health Interview Survey and linked state/county-level data, this study analyzed data on 61,732 foreign-born adults from nine regions of birth. Three-level multilevel modeling (state > county > individual) was conducted. The age-adjusted percentages of foreign-born adults who delayed/missed necessary health care because of cost varied by region of birth, ranging from 7.0% (Southeast Asia) and 11.9% (Europe) to 15.5% (Mexico/Central America/Caribbean) and 16.7% (the Middle East). However, after controlling for geographic clustering and other individual-level covariates (e.g., insurance), adults from Mexico/Central America/Caribbean were less likely to delay or not receive necessary care compared to their counterparts from all other parts of the world except for those from Asian regions. This study implies that disparities can be reduced if some known risk factors (e.g., insurance) are improved among foreign-born adults. © The Author(s) 2016.

Regional Contrasts of the Warming Rate over Land Significantly Depend on the Calculation Methods of Mean Air Temperature

NASA Astrophysics Data System (ADS)

Wang, Kaicun; Zhou, Chunlüe

2016-04-01

Global analyses of surface mean air temperature (Tm) are key datasets for climate change studies and provide fundamental evidences for global warming. However, the causes of regional contrasts in the warming rate revealed by such datasets, i.e., enhanced warming rates over the northern high latitudes and the "warming hole" over the central U.S., are still under debate. Here we show these regional contrasts depends on the calculation methods of Tm. Existing global analyses calculated Tm from daily minimum and maximum temperatures (T2). We found that T2 has a significant standard deviation error of 0.23 °C/decade in depicting the regional warming rate from 2000 to 2013 but can be reduced by two-thirds using Tm calculated from observations at four specific times (T4), which samples diurnal cycle of land surface air temperature more often. From 1973 to 1997, compared with T4, T2 significantly underestimated the warming rate over the central U.S. and overestimated the warming rate over the northern high latitudes. The ratio of the warming rate over China to that over the U.S. reduces from 2.3 by T2 to 1.4 by T4. This study shows that the studies of regional warming can be substantially improved by T4 instead of T2.

CMOS foveal image sensor chip

NASA Technical Reports Server (NTRS)

Scott, Peter (Inventor); Sridhar, Ramalingam (Inventor); Bandera, Cesar (Inventor); Xia, Shu (Inventor)

2002-01-01

A foveal image sensor integrated circuit comprising a plurality of CMOS active pixel sensors arranged both within and about a central fovea region of the chip. The pixels in the central fovea region have a smaller size than the pixels arranged in peripheral rings about the central region. A new photocharge normalization scheme and associated circuitry normalizes the output signals from the different size pixels in the array. The pixels are assembled into a multi-resolution rectilinear foveal image sensor chip using a novel access scheme to reduce the number of analog RAM cells needed. Localized spatial resolution declines monotonically with offset from the imager's optical axis, analogous to biological foveal vision.

Masking of central diabetes insipidus and hypogonadotrophic hypogonadism by germ cell tumour in suprasellar--pineal region.

PubMed

Isa, S H Md; Wong, M; Khalid, B A K

2006-12-01

A patient with beta hCG-secreting germ cell carcinoma of the pineal and suprasellar regions presented with hydrocephalus, Parinaud's syndrome, hypopituitarism and polyuria. Central diabetes insipidus was strongly suspected although the water deprivation test was not diagnostic. The polyuria however, responded to ADH analogue when the hypothyroidism and hypocortisolism were treated. Pubertal development was evident and serum testosterone was normal despite the low FSH/LH, suggesting hCG stimulation of Leydig cells. This case illustrates that a beta hCG-germ cell tumour of the suprasellar region causing hypopituitarism can mask the presence of central diabetes insipidus and hypogonadotrophic hypogonadism.

Groundwater-Surface water interaction in agricultural watershed that encompasses dense network of High Capacity wells

NASA Astrophysics Data System (ADS)

Talib, A.; Desai, A. R.

2017-12-01

The Central Sands region of Wisconsin is characterized by productive trout streams, lakes, farmland and forest. However, stream channelization, past wetland drainage, and ground water withdrawals have disrupted the hydrology of this Central Sands region. Climatically driven conditions in last decade (2000-2008) alone are unable to account for the severely depressed water levels. Increased interception and evapotranspiration from afforested areas in central sand Wisconsin may also be culprit for reduced water recharge. Hence, there is need to study the cumulative effects of changing precipitation patterns, groundwater withdrawals, and forest evapotranspiration to improve projections of the future of lake levels and water availability in this region. Here, the SWAT-MODFLOW coupled model approach was applied at large spatio-temporal scale. The coupled model fully integrates a watershed model (SWAT) with a groundwater flow model (MODFLOW). Surface water and ground water flows were simulated integratively at daily time step to estimate the groundwater discharge to the stream network in Central Sands that encompasses high capacity wells. The model was calibrated (2010-2013) and validated (2014-2017) based on streamflow, groundwater extraction, and water table elevation. As the long-term trends in some of the primary drivers is presently ambiguous in Central Sands under future climate, as is the case for total precipitation or timing of precipitation, we relied on a sensitivity student to quantitatively access how primary and secondary drivers may influence future net groundwater recharge. We demonstrate how such an approach could then be coupled with decision-making models to evaluate the effectiveness of groundwater withdrawal policies under a changing climate.

Impact of Desiccation of Aral Sea on the Regional Climate of Central Asia Using WRF Model

NASA Astrophysics Data System (ADS)

Sharma, Ashish; Huang, Huei-Ping; Zavialov, Peter; Khan, Valentina

2018-01-01

This study explores the impacts of the desiccation of the Aral Sea and large-scale climate change on the regional climate of Central Asia in the post-1960 era. A series of climate downscaling experiments for the 1960's and 2000's decades were performed using the Weather Research and Forecast model at 12-km horizontal resolution. To quantify the impacts of the changing surface boundary condition, a set of simulations with an identical lateral boundary condition but different extents of the Aral Sea were performed. It was found that the desiccation of the Aral Sea leads to more snow (and less rain) as desiccated winter surface is relatively much colder than water surface. In summer, desiccation led to substantial warming over the Aral Sea. These impacts were largely confined to within the area covered by the former Aral Sea and its immediate vicinity, although desiccation of the Sea also led to minor cooling over the greater Central Asia in winter. A contrasting set of simulations with an identical surface boundary condition but different lateral boundary conditions produced more identifiable changes in regional climate over the greater Central Asia which was characterized by a warming trend in both winter and summer. Simulations also showed that while the desiccation of the Aral Sea has significant impacts on the local climate over the Sea, the climate over the greater Central Asia on inter-decadal time scale was more strongly influenced by the continental or global-scale climate change on that time scale.

Shore zone land use and land cover: Central Atlantic Regional Ecological Test Site

USGS Publications Warehouse

Dolan, R.; Hayden, B.P.; Vincent, C.L.

1974-01-01

Anderson's 1972 United States Geological Survey classification in modified form was applied to the barrier-island coastline within the CARETS region. High-altitude, color-infrared photography of December, 1972, and January, 1973, served as the primary data base in this study. The CARETS shore zone studied was divided into six distinct geographical regions; area percentages for each class in the modified Anderson classification are presented. Similarities and differences between regions are discussed within the framework of man's modification of these landscapes. The results of this study are presented as a series of 19 maps of land-use categories. Recommendations are made for a remote-sensing system for monitoring the CARETS shore zone within the context of the dynamics of the landscapes studied.

Residential grid-connected photovoltaics adoption in north central Texas: Lessons from the Solarize Plano project

NASA Astrophysics Data System (ADS)

Jack, Katherine G.

Residential Grid-Connected Photovoltaics (GPV) systems hold remarkable promise in their potential to reduce energy use, air pollution, greenhouse gas emissions, and energy costs to consumers, while also providing grid efficiency and demand-side management benefits to utilities. Broader adoption of customer-sited GPV also has the potential to transform the traditional model of electricity generation and delivery. Interest and activity has grown in recent years to promote GPV in north central Texas. This study employs a mixed methods design to better understand the status of residential GPV adoption in the DFW area, and those factors influencing a homeowner's decision of whether or not to install a system. Basic metrics are summarized, including installation numbers, distribution and socio-demographic information for the case study city of Plano, the DFW region, Texas, and the United States. Qualitative interview methods are used to gain an in-depth understanding of the factors influencing adoption for the Solarize Plano case study participants; to evaluate the effectiveness of the Solarize Plano program; and to identify concepts that may be regionally relevant. Recommendations are presented for additional research that may advance GPV adoption in north central Texas.

Congenital transmission of Trypanosoma cruzi in central Brazil. A study of 1,211 individuals born to infected mothers

PubMed Central

Luquetti, Alejandro O; Tavares, Suelene Brito do Nascimento; Siriano, Liliane da Rocha; de Oliveira, Rozângela Amaral; Campos, Dayse Elizabeth; de Morais, Cicilio Alves; de Oliveira, Enio Chaves

2015-01-01

Transmission of Trypanosoma cruzi during pregnancy is estimated to occur in less than 20% of infected mothers; however, the etiopathogenesis is not completely understood. The Centre for Studies on Chagas Disease provides confirmation of T. cruzi infection for individuals living in central Brazil. In this retrospective hospital-based study, all requests for diagnosis of T. cruzi infection in individuals less than 21 years old from 1994-2014 were searched. We end with 1,211 individuals and their respective infected mothers. Congenital transmission of infection was confirmed in 24 individuals (2%) in central Brazil, an area where the main T. cruzi lineage circulating in humans is TcII. This low prevalence of congenital Chagas disease is discussed in relation to recent findings in the south region of Brazil, where TcV is the main lineage and congenital transmission has a higher prevalence (approximately 5%), similar to frequencies reported in Argentina, Paraguay and Bolivia. This is the first report to show geographical differences in the rates of congenital transmission of T. cruzi and the relationship between the prevalence of congenital transmission and the type of Tc prevalent in each region. PMID:25993506

Eddy-induced Sea Surface Salinity changes in the tropical Pacific

NASA Astrophysics Data System (ADS)

Delcroix, T. C.; Chaigneau, A.; Soviadan, D.; Boutin, J.

2017-12-01

We analyse the Sea Surface Salinity (SSS) signature of westward propagating mesoscale eddies in the tropical Pacific by collocating 5 years (2010-2015) of SMOS (Soil Moisture and Ocean Salinity) SSS and altimetry-derived sea level anomalies. The main characteristics of mesoscale eddies are first identified in SLA maps. Composite analyses in the Central and Eastern ITCZ regions then reveal regionally dependent impacts with opposite SSS anomalies for the cyclonic and anticyclonic eddies. In the Central region (where we have the largest meridional SSS gradient), we found dipole-like SSS changes with maximum anomalies on the leading edge of the eddy. In the Eastern region (where we have the largest near-surface vertical salinity gradient) we found monopole-like SSS changes with maximum anomalies in the eddy centre. These dipole/monopole patterns and the rotational sense of eddies suggest the dominant role of horizontal and vertical advection in the Central and Eastern ITCZ regions, respectively.

THE LBA PROJECT: NUTRIENT CYCLES AND TRACE GAS EXCHANGE IN SAVANNAS OF CENTRAL BRAZIL

EPA Science Inventory

The Cerrado of central Brazil is one of the largest savannah regions on Earth. The stressors affecting ecosystems in this region, including deforestation, fire, soil degradation, unwise agricultural practices, climate change, and urbanization, are all experienced in many U. S. ec...

Irritable Bowel Syndrome in female patients is associated with alterations in structural brain networks

PubMed Central

Labus, Jennifer; Dinov, Ivo D.; Jiang, Zhiguo; Ashe-McNalley, Cody; Zamanyan, Alen; Shi, Yonggang; Hong, Jui-Yang; Gupta, Arpana; Tillisch, Kirsten; Ebrat, Bahar; Hobel, Sam; Gutman, Boris A.; Joshi, Shantanu; Thompson, Paul M.; Toga, Arthur W.; Mayer, Emeran A.

2014-01-01

Alterations in gray matter (GM) density/ volume and cortical thickness (CT) have been demonstrated in small and heterogeneous samples of subjects with different chronic pain syndromes, including irritable bowel syndrome (IBS). Aggregating across 7 structural neuroimaging studies conducted at UCLA between August 2006 and April 2011, we examined group differences in regional GM volume in 201 predominantly premenopausal female subjects (82 IBS, mean age: 32 ± 10 SD, 119 Healthy Controls [HCs], 30± 10 SD). Applying graph theoretical methods and controlling for total brain volume, global and regional properties of large-scale structural brain networks were compared between IBS and HC groups. Relative to HCs, the IBS group had lower volumes in bilateral superior frontal gyrus, bilateral insula, bilateral amygdala, bilateral hippocampus, bilateral middle orbital frontal gyrus, left cingulate, left gyrus rectus, brainstem, and left putamen. Higher volume was found for the left postcentral gyrus. Group differences were no longer significant for most regions when controlling for Early Trauma Inventory global score with the exception of the right amygdala and the left post central gyrus. No group differences were found for measures of global and local network organization. Compared to HCs, the right cingulate gyrus and right thalamus were identified as significantly more critical for information flow. Regions involved in endogenous pain modulation and central sensory amplification were identified as network hubs in IBS. Overall, evidence for central alterations in IBS was found in the form of regional GM volume differences and altered global and regional properties of brain volumetric networks. PMID:24076048

Upper Miocene-Pliocene provenance evolution of the Central Canyon in northwestern South China Sea

NASA Astrophysics Data System (ADS)

Cui, Yuchi; Shao, Lei; Qiao, Peijun; Pei, Jianxiang; Zhang, Daojun; Tran, Huyen

2018-06-01

Provenance studies of the Central Canyon, Qiongdongnan Basin has provided significant insights into paleographic and sedimentology research of the South China Sea (SCS). A suite of geochemical approaches mainly including rare earth elemental (REE) analysis and detrital zircon U-Pb dating has been systematically applied to the "source-to-sink" system involving our upper Miocene-Pliocene Central Canyon sediments and surrounding potential source areas. Based on samples tracing the entire course of the Central Canyon, REE distribution patterns indicate that the western channel was generally characterized by positive Eu anomalies in larger proportion, in contrast to the dominance of negative values of its eastern side during late Miocene-Pliocene. Additionally, for the whole canyon and farther regions of Qiongdongnan Basin, the number of samples bearing negative Eu anomalies tended to increase within younger geological strata. On the other hand, U-Pb geochronology results suggest a wide Proterozoic to Mesozoic age range with peak complexity in Yanshanian, Indosinian, Caledonian and Jinningian periods. However in detail, age combination of most western samples displayed older-age signatures than the eastern. To make it more evidently, western boreholes of the Central Canyon are mainly characterized with confined Indosinian and Caledonian clusters which show great comparability with mafic-to-ultramafic source of Kontum Massif of Central Vietnam, while eastern samples largely bear with distinguishable Yanshanian and Indosinian peaks which more resemble with Hainan Island. Based on geochemistry and geochronology analyses, two significant suppliers and sedimentary infilling processes are generated: (1) the Indosinian collision orogenic belt in central-northern Vietnam, Indochina has ever played significant role in Central Canyon sedimentary evolution, (2) Hainan Island once as a typical provenance restricted within eastern Central Canyon, has been enlarging its influence into the whole channel, even into the farther western regions of Qiongdongnan Basin.

Observed Local Impacts of Global Irrigation on Surface Temperature

NASA Astrophysics Data System (ADS)

Chen, L.; Dirmeyer, P.

2017-12-01

Agricultural irrigation has significant potential for altering local climate through reducing soil albedo, increasing evapotranspiration, and enabling greater leaf area. Numerous studies using regional or global climate models have demonstrated the cooling effects of irrigation on mean and extreme temperature, especially over regions where irrigation is extensive. However, these model-based results have not been validated due to the limitations of observational datasets. In this study, multiple satellite-based products, including the Moderate Resolution Imaging Spectroradiometer (MODIS) and Soil Moisture Active Passive (SMAP) data sets, are used to isolate and quantify the local impacts of irrigation on surface climate over the irrigated regions, which are derived from the Global Map of Irrigation Areas (GMIA). The relationships among soil moisture, albedo, evapotranspiration, and surface temperature are explored. Strong evaporative cooling of irrigation on daytime surface temperature is found over the arid and semi-arid regions, such as California's Central Valley, the Great Plains, and central Asia. However, the cooling effects are less evident in most areas of eastern China, India, and the Lower Mississippi River Basin in spite of extensive irrigation over these regions. Results are also compared with irrigation experiments using the Community Earth System Model (CESM) to assess the model's ability to represent land-atmosphere interactions in regards to irrigation.

Site selection and nest survival of the Bar-Headed Goose (Anser indicus) on the Mongolian Plateau

USGS Publications Warehouse

Batbayar, Nyambayar; Takekawa, John Y.; Natsagdorj, Tseveenmyadag; Spragens, Kyle A.; Xiao, Xiamgming

2014-01-01

Waterbirds breeding on the Mongolian Plateau in Central Asia must find suitable wetland areas for nesting in a semiarid region characterized by highly variable water conditions. The first systematic nesting study of a waterbird dependent on this region for breeding was conducted on the Bar-headed Goose (Anser indicus). The purpose of this study was to document Bar-headed Goose nesting locations, characterize nests and nesting strategies, and estimate daily nest survival (n = 235 nests) from eight areas of west-central Mongolia across three summers (2009–2011) using a modified Mayfield estimator. Bar-headed Goose daily nest survival ranged from 0.94 to 0.98, with a 3-year average nest success of 42.6% during incubation. Bar-headed Geese were found to primarily nest on isolated pond and lake islands as previously reported, but were also documented regularly, though less frequently, along rocky cliffs in several regions of west-central Mongolia. Daily nest survival was higher for cliff nests than for island nests. Information-theoretic models indicated that nest survival decreased with nest age and varied annually with changing environmental conditions. Results of this study suggest that while Bar-headed Geese primarily rely on nesting island sites these sites may be more susceptible to anthropogenic disturbance and predation events influenced by seasonal variation in environmental conditions, and that higher daily nest survival values documented for the less frequent cliff nest strategy may provide an important alternative strategy during poor island nest success years. Thus, conservation efforts for this and other waterbird species in the semiarid region should be focused on conserving nesting islands and protecting them from disturbance in areas of high livestock densities experiencing a rapidly warming climate.

Salmonella Bacteremia Among Children in Central and Northwest Nigeria, 2008–2015

PubMed Central

Obaro, Stephen K.; Hassan-Hanga, Fatimah; Olateju, Eyinade K.; Umoru, Dominic; Lawson, Lovett; Olanipekun, Grace; Ibrahim, Sadeeq; Munir, Huda; Ihesiolor, Gabriel; Maduekwe, Augustine; Ohiaeri, Chinatu; Adetola, Anthony; Shetima, Denis; Jibir, Binta W.; Nakaura, Hafsat; Kocmich, Nicholas; Ajose, Therasa; Idiong, David; Masokano, Kabir; Ifabiyi, Adeyemi; Ihebuzor, Nnenna; Chen, Baojiang; Meza, Jane; Akindele, Adebayo; Rezac-Elgohary, Amy; Olaosebikan, Rasaq; Suwaid, Salman; Gambo, Mahmoud; Alter, Roxanne; Davies, Herbert D.; Fey, Paul D.

2015-01-01

Background. Etiologic agents of childhood bacteremia remain poorly defined in Nigeria. The absence of such data promotes indiscriminate use of antibiotics and delays implementation of appropriate preventive strategies. Methods. We established diagnostic laboratories for bacteremia surveillance at regional sites in central and northwest Nigeria. Acutely ill children aged <5 years with clinically suspected bacteremia were evaluated at rural and urban clinical facilities in the Federal Capital Territory, central region and in Kano, northwest Nigeria. Blood was cultured using the automated Bactec incubator system. Results. Between September 2008 and April 2015, we screened 10 133 children. Clinically significant bacteremia was detected in 609 of 4051 (15%) in the northwest and 457 of 6082 (7.5%) in the central region. Across both regions, Salmonella species account for 24%–59.8% of bacteremias and are the commonest cause of childhood bacteremia, with a predominance of Salmonella enterica serovar Typhi. The prevalence of resistance to ampicillin, chloramphenicol, and cotrimoxazole was 38.11%, with regional differences in susceptibility to different antibiotics but high prevalence of resistance to readily available oral antibiotics. Conclusions. Salmonella Typhi is the leading cause of childhood bacteremia in central Nigeria. Expanded surveillance is planned to define the dynamics of transmission. The high prevalence of multidrug-resistant strains calls for improvement in environmental sanitation in the long term and vaccination in the short term. PMID:26449948

International Collaboration and Spatial Dynamics of US Patenting in Central and Eastern Europe 1981-2010

PubMed Central

Lengyel, Balázs; Leskó, Mariann

2016-01-01

How did post-socialist transition and a parallel shift in international labor division restructure regional innovation systems in Central and Eastern Europe? This question is increasingly important, because current EU innovation policy is combined with regional development in Smart Specialization Strategies; however, spatial trends of innovation in Central and Eastern Europe are not fully understood which might lead to less than perfectly efficient policy. In this paper we describe the spatial dynamics of inventor activity in the Czech Republic, Hungary, Poland and Slovakia between 1981 and 2010 –a period that covers both the late socialist era and the post-socialist transition. Cleaning and analyzing the publicly available data from the United States Patent and Trademark Office we illustrate that Central and Eastern European patents made in international co-operations with partners outside the region receive more citations than those Central and Eastern European patents that lack international co-operation. Furthermore, the technological portfolio of the former patents has become increasingly independent from the technological portfolio of the latter class. A town-level analysis of the applicant-inventor ties reveals that inventors have started to work for foreign assignees in those towns where no innovation activity had been recorded before. However, the positive effect does not last long and patenting seems to be only periodic in the majority of these towns. Therefore, innovation policy in Central and Eastern European countries, as well as in other less developed regions, shall foster synergies between international and domestic collaborations in order to decrease regional disparities in patenting. PMID:27846288

International Collaboration and Spatial Dynamics of US Patenting in Central and Eastern Europe 1981-2010.

PubMed

Lengyel, Balázs; Leskó, Mariann

2016-01-01

How did post-socialist transition and a parallel shift in international labor division restructure regional innovation systems in Central and Eastern Europe? This question is increasingly important, because current EU innovation policy is combined with regional development in Smart Specialization Strategies; however, spatial trends of innovation in Central and Eastern Europe are not fully understood which might lead to less than perfectly efficient policy. In this paper we describe the spatial dynamics of inventor activity in the Czech Republic, Hungary, Poland and Slovakia between 1981 and 2010 -a period that covers both the late socialist era and the post-socialist transition. Cleaning and analyzing the publicly available data from the United States Patent and Trademark Office we illustrate that Central and Eastern European patents made in international co-operations with partners outside the region receive more citations than those Central and Eastern European patents that lack international co-operation. Furthermore, the technological portfolio of the former patents has become increasingly independent from the technological portfolio of the latter class. A town-level analysis of the applicant-inventor ties reveals that inventors have started to work for foreign assignees in those towns where no innovation activity had been recorded before. However, the positive effect does not last long and patenting seems to be only periodic in the majority of these towns. Therefore, innovation policy in Central and Eastern European countries, as well as in other less developed regions, shall foster synergies between international and domestic collaborations in order to decrease regional disparities in patenting.

DNA barcodes identify Central Asian Colias butterflies (Lepidoptera, Pieridae).

PubMed

Laiho, Juha; Ståhls, Gunilla

2013-12-30

A majority of the known Colias species (Lepidoptera: Pieridae, Coliadinae) occur in the mountainous regions of Central-Asia, vast areas that are hard to access, rendering the knowledge of many species limited due to the lack of extensive sampling. Two gene regions, the mitochondrial COI 'barcode' region and the nuclear ribosomal protein RpS2 gene region were used for exploring the utility of these DNA markers for species identification. A comprehensive sampling of COI barcodes for Central Asian Colias butterflies showed that the barcodes facilitated identification of most of the included species. Phylogenetic reconstruction based on parsimony and Neighbour-Joining recovered most species as monophyletic entities. For the RpS2 gene region species-specific sequences were registered for some of the included Colias spp. Nevertheless, this gene region was not deemed useful as additional molecular 'barcode'. A parsimony analysis of the combined COI and RpS2 data did not support the current subgeneric classification based on morphological characteristics.

DNA barcodes identify Central Asian Colias butterflies (Lepidoptera, Pieridae)

PubMed Central

Laiho, Juha; Ståhls, Gunilla

2013-01-01

Abstract A majority of the known Colias species (Lepidoptera: Pieridae, Coliadinae) occur in the mountainous regions of Central-Asia, vast areas that are hard to access, rendering the knowledge of many species limited due to the lack of extensive sampling. Two gene regions, the mitochondrial COI ‘barcode’ region and the nuclear ribosomal protein RpS2 gene region were used for exploring the utility of these DNA markers for species identification. A comprehensive sampling of COI barcodes for Central Asian Colias butterflies showed that the barcodes facilitated identification of most of the included species. Phylogenetic reconstruction based on parsimony and Neighbour-Joining recovered most species as monophyletic entities. For the RpS2 gene region species-specific sequences were registered for some of the included Colias spp. Nevertheless, this gene region was not deemed useful as additional molecular ‘barcode’. A parsimony analysis of the combined COI and RpS2 data did not support the current subgeneric classification based on morphological characteristics. PMID:24453557

Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.

PubMed

Naudí, Alba; Cabré, Rosanna; Dominguez-Gonzalez, Mayelin; Ayala, Victoria; Jové, Mariona; Mota-Martorell, Natalia; Piñol-Ripoll, Gerard; Gil-Villar, Maria Pilar; Rué, Montserrat; Portero-Otín, Manuel; Ferrer, Isidre; Pamplona, Reinald

2017-05-01

Lipids played a determinant role in the evolution of the brain. It is postulated that the morphological and functional diversity among neural cells of the human central nervous system (CNS) is projected and achieved through the expression of particular lipid profiles. The present study was designed to evaluate the differential vulnerability to oxidative stress mediated by lipids through a cross-regional comparative approach. To this end, we compared 12 different regions of CNS of healthy adult subjects, and the fatty acid profile and vulnerability to lipid peroxidation, were determined by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS), respectively. In addition, different components involved in PUFA biosynthesis, as well as adaptive defense mechanisms against lipid peroxidation, were also measured by western blot and immunohistochemistry, respectively. We found that: i) four fatty acids (18.1n-9, 22:6n-3, 20:1n-9, and 18:0) are significant discriminators among CNS regions; ii) these differential fatty acid profiles generate a differential selective neural vulnerability (expressed by the peroxidizability index); iii) the cross-regional differences for the fatty acid profiles follow a caudal-cranial gradient which is directly related to changes in the biosynthesis pathways which can be ascribed to neuronal cells; and iv) the higher the peroxidizability index for a given human brain region, the lower concentration of the protein damage markers, likely supported by the presence of adaptive antioxidant mechanisms. In conclusion, our results suggest that there is a region-specific vulnerability to lipid peroxidation and offer evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the human central nervous system. Copyright © 2017 Elsevier B.V. All rights reserved.

Inherited weaknesses control deformation in the flat slab region of Central Argentina

NASA Astrophysics Data System (ADS)

Stevens, A.; Carrapa, B.; Larrovere, M.; Aciar, R. H.

2015-12-01

The Sierras Pampeanas region of west-central Argentina has long been considered a geologic type-area for flat-slab induced thick-skinned deformation. Frictional coupling between the horizontal subducting plate and South American lithosphere from ~12 Ma to the present provides an obvious causal mechanism for the basement block uplifts that characterize this region. New low temperature thermochronometry data show basement rocks from the central Sierras Pampeanas (~ longitude 66 ̊ W) including Sierras Cadena de Paiman, Velasco and Mazan retain a cooling history of Paleozoic - Mesozoic tectonics events. Results from this study indicate that less than 2 km of basement has been exhumed since at least the Mesozoic. These trends recorded by both apatite fission track (AFT) and apatite helium (AHe) thermochronometry suggest that recent Mio-Pliocene thick-skinned deformation associated with flat-slab subduction follow inherited zones of weakness from Paleozoic terrane sutures and shear zones and Mesozoic rifting. If a Cenozoic foreland basin exisited in this region, its thickness was minimal and was controlled by paleotopography. Pre-Cenozoic cooling ages in these ranges that now reach as high as 4 km imply significant exhumation of basement rocks before the advent of flat slab subduction in the mid-late Miocene. It also suggests that thick-skinned deformation associated with flat slab subduction may at least be facilitated by inherited crustal-scale weaknesses. At the most, pre-existing zones of weakness may be required in regions of thick-skinned deformation. Although flat-slab subduction plays an important role in the exhumation of the Sierras Pampeanas, it is likely not the sole mechanism responsible for thick-skinned deformation in this region. This insight sheds light on the interpretation of modern and ancient regions of thick-skinned deformation in Cordilleran systems.

Crustal velocity structure of central Gansu Province from regional seismic waveform inversion using firework algorithm

NASA Astrophysics Data System (ADS)

Chen, Yanyang; Wang, Yanbin; Zhang, Yuansheng

2017-04-01

The firework algorithm (FWA) is a novel swarm intelligence-based method recently proposed for the optimization of multi-parameter, nonlinear functions. Numerical waveform inversion experiments using a synthetic model show that the FWA performs well in both solution quality and efficiency. We apply the FWA in this study to crustal velocity structure inversion using regional seismic waveform data of central Gansu on the northeastern margin of the Qinghai-Tibet plateau. Seismograms recorded from the moment magnitude ( M W) 5.4 Minxian earthquake enable obtaining an average crustal velocity model for this region. We initially carried out a series of FWA robustness tests in regional waveform inversion at the same earthquake and station positions across the study region, inverting two velocity structure models, with and without a low-velocity crustal layer; the accuracy of our average inversion results and their standard deviations reveal the advantages of the FWA for the inversion of regional seismic waveforms. We applied the FWA across our study area using three component waveform data recorded by nine broadband permanent seismic stations with epicentral distances ranging between 146 and 437 km. These inversion results show that the average thickness of the crust in this region is 46.75 km, while thicknesses of the sedimentary layer, and the upper, middle, and lower crust are 3.15, 15.69, 13.08, and 14.83 km, respectively. Results also show that the P-wave velocities of these layers and the upper mantle are 4.47, 6.07, 6.12, 6.87, and 8.18 km/s, respectively.

North Central IPM Center

Science.gov Websites

) solutions, based in the North Central region. North Central IPM Center Invasive Plants in Trade Working webpage to learn about the North Central IPM Center's grants program and other IPM-related funding Tribal IPM Urban Ag IPM Partners In IPM Working Groups Critical Issues Projects North Central IPM

Two Informative Cases of Q-Switched Laser Eye Injury

DTIC Science & Technology

1991-07-01

produced a central retinal scar at the parafoveal lesion sites and resulted in retinal traction over an extensive region of the retina with local retinal...over an extensive region of the retina with local retinal hole formation at the edge of the central scar. A central arucate absolute scotoma appeared...vision caused by laser exposure of the retina depends primarily on the aruvunt of energy absorbed in the eye - the higher the energy, the higher the

Trading genes along the silk road: mtDNA sequences and the origin of central Asian populations.

PubMed Central

Comas, D; Calafell, F; Mateu, E; Pérez-Lezaun, A; Bosch, E; Martínez-Arias, R; Clarimon, J; Facchini, F; Fiori, G; Luiselli, D; Pettener, D; Bertranpetit, J

1998-01-01

Central Asia is a vast region at the crossroads of different habitats, cultures, and trade routes. Little is known about the genetics and the history of the population of this region. We present the analysis of mtDNA control-region sequences in samples of the Kazakh, the Uighurs, the lowland Kirghiz, and the highland Kirghiz, which we have used to address both the population history of the region and the possible selective pressures that high altitude has on mtDNA genes. Central Asian mtDNA sequences present features intermediate between European and eastern Asian sequences, in several parameters-such as the frequencies of certain nucleotides, the levels of nucleotide diversity, mean pairwise differences, and genetic distances. Several hypotheses could explain the intermediate position of central Asia between Europe and eastern Asia, but the most plausible would involve extensive levels of admixture between Europeans and eastern Asians in central Asia, possibly enhanced during the Silk Road trade and clearly after the eastern and western Eurasian human groups had diverged. Lowland and highland Kirghiz mtDNA sequences are very similar, and the analysis of molecular variance has revealed that the fraction of mitochondrial genetic variance due to altitude is not significantly different from zero. Thus, it seems unlikely that altitude has exerted a major selective pressure on mitochondrial genes in central Asian populations. PMID:9837835

National Hydroelectric Power Resources Study: Volume XVII: Regional Assessment: East Central Area Reliability Coordination Agreement I

DTIC Science & Technology

1981-09-01

Cincinnati, Ohio 45201 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASK AREA a WORK UNIT NUMBERS Same as No. 7 above. It...water supply, navigation and base flow stabilization; and • Insures that existing public utilization and environmental values of project lands and...Coordination Group and the Kentucky-Indiana sub-region each contained about 18 percent of the 1970 ECAR region population. The industrial sectors of

The Evolution History of South China Sea: a Synthesis of Recent Geophysical, Geological, and Geochemical Results

NASA Astrophysics Data System (ADS)

Xue, M.; Li, L.; Chen, L.

2016-12-01

South China Sea (SCS) is located in the continental margin of Eurasia plate, where different geological blocks/tectonic plates interact. The dynamic mechanism of the formation of South China Sea (SCS) has been debated for decades. In this study, we first synthesize our geophysical results obtained in South China Sea, including an updated 3D velocity model from surface tomography using surrounding land stations and regional earthquakes, and shear wave splitting results obtained at surrounding land stations and OBS, using local, regional, and teleseismic earthquakes. The observed splitting results in South China Sea are complex: the fast polarization direction beneath the central basin is approximately NE-SW, nearly parallel to the extinct ridge in the central basin of SCS; however, the fast axis within the slab is trench-parallel outside the ridge subduction region. In 3D velocity models, subducting slabs are observed as dipping high velocity anomalies, and discontinuous low velocities are observed above the subduction slab, as well as in the basin. How the splitting observations are connected with the velocity models? How observations are linked to one another? How are the observations in central basin linked with surrounding region? We are aiming to link these observations themselves as well as with newly published results from geophysics, geochemistry, and geology in this region. Such a synthesis will improve our understanding about the evolution of South China Sea and facilitate new ideas.

Benchmarking Terrestrial Ecosystem Models in the South Central US

NASA Astrophysics Data System (ADS)

Kc, M.; Winton, K.; Langston, M. A.; Luo, Y.

2016-12-01

Ecosystem services and products are the foundation of sustainability for regional and global economy since we are directly or indirectly dependent on the ecosystem services like food, livestock, water, air, wildlife etc. It has been increasingly recognized that for sustainability concerns, the conservation problems need to be addressed in the context of entire ecosystems. This approach is even more vital in the 21st century with formidable increasing human population and rapid changes in global environment. This study was conducted to find the state of the science of ecosystem models in the South-Central region of US. The ecosystem models were benchmarked using ILAMB diagnostic package developed as a result of International Land Model Benchmarking (ILAMB) project on four main categories; viz, Ecosystem and Carbon Cycle, Hydrology Cycle, Radiation and Energy Cycle and Climate forcings. A cumulative assessment was generated with weighted seven different skill assessment metrics for the ecosystem models. This synthesis on the current state of the science of ecosystem modeling in the South-Central region of US will be highly useful towards coupling these models with climate, agronomic, hydrologic, economic or management models to better represent ecosystem dynamics as affected by climate change and human activities; and hence gain more reliable predictions of future ecosystem functions and service in the region. Better understandings of such processes will increase our ability to predict the ecosystem responses and feedbacks to environmental and human induced change in the region so that decision makers can make an informed management decisions of the ecosystem.

The contribution of the Global Change Observatory Central Asia to seismic hazard and risk assessment in the Central Asian region

NASA Astrophysics Data System (ADS)

Parolai, S.; Bindi, D.; Haberland, C. A.; Pittore, M.; Pilz, M.; Rosenau, M.; Schurr, B.; Wieland, M.; Yuan, X.

2012-12-01

Central Asia has one of the world's highest levels of earthquake hazard, owing to its exceptionally high deformation rates. Moreover, vulnerability to natural disasters in general is increasing, due to rising populations and a growing dependence on complex lifelines and technology. Therefore, there is an urgent need to undertake seismic hazard and risk assessment in this region, while at the same time improving upon existing methodologies, including the consideration of temporal variability in the seismic hazard, and in structural and social vulnerability. Over the last few years, the German Research Center for Geosciences (GFZ), in collaboration with local partners, has initiated a number of scientific activities within the framework of the Global Change Observatory Central Asia (GCO-CA). The work is divided into projects with specific concerns: - The installation and maintenance of the Central-Asian Real-time Earthquake MOnitoring Network (CAREMON) and the setup of a permanent wireless mesh network for structural health monitoring in Bishkek. - The TIPAGE and TIPTIMON projects focus on the geodynamics of the Tien-Shan, Pamir and Hindu Kush region, the deepest and most active intra-continental subduction zone in the world. The work covers time scales from millions of years to short-term snapshots based on geophysical measurements of seismotectonic activity and of the physical properties of the crust and upper mantle, as well as their coupling with other surface processes (e.g., landslides). - Existing risk analysis methods assume time-independent earthquake hazard and risk, although temporal changes are likely to occur due to, for example, co- and post-seismic changes in the regional stress field. We therefore aim to develop systematic time-dependent hazard and risk analysis methods in order to undertake the temporal quantification of earthquake activity (PROGRESS). - To improve seismic hazard assessment for better loss estimation, detailed site effects studies are necessary. Temporary seismic networks have been installed in several Central Asian cities (Bishkek and Karakol, Kyrgyzstan; Dushanbe, Tajikistan; Tashkent, Uzbekistan) within the framework of the Earthquake Model Central Asia (EMCA), a regional program of the Global Earthquake Model (GEM). The empirically estimated site effects have already helped to improve real-time risk scenarios for Bishkek and will be applied to other major cities. - A crucial requirement for disaster risk reduction involves the analysis of the vulnerability of existing building inventories. Whereas traditional approaches are very time- and cost-consuming, and even impossible given the high rate of urbanization in Central Asian capitals, our integrated approach is based on satellite remote sensing and ground-based omni-directional imaging, providing building inventories and thus structural vulnerability over large areas (EMCA, GEM-IDCT). All mentioned activities are carried out within the framework of cooperation between GFZ and regional national institutes, in particular the Central Asian Institute for Applied Geosciences. Altogether, this comprehensive and long-term risk analyses and research program will lead to a better understanding of the coupling of endogene and exogene processes and the identification of their impact on society.

Anatomy of the interosseous region of the sacroiliac joint.

PubMed

Rosatelli, Alessandro L; Agur, Anne M; Chhaya, Sam

2006-04-01

Anatomical study of the interosseous region of the sacroiliac joint (SIJ) complex. To document and quantify the surface topography of the interosseous region of the SIJ. A review of the literature reveals that little consideration has been given to the interosseous region of the SIJ anatomically, biomechanically, and clinically. The interosseous region of 11 cadaveric specimens (9 formalin embalmed and 2 fresh frozen) were studied. Ten specimens were 55 years of age or older and 1 was 20 years old. To view the interosseous surfaces of the sacrum and ilium the specimens were either axially sectioned (1-cm slices) or disarticulated. One fresh-frozen and 6 embalmed specimens were disarticulated and the remainder axially sectioned. The topography (surface ridging and areas of ossification) of the interosseous region was documented in all specimens and in 2 specimens the surfaces were 3-dimensionally reconstructed using modeling and animation software (MAYA; Autodesk, Inc, San Rafael, CA). Surface characteristics of the SIJ complex observed in specimens 55 years of age or older included moderate to extensive ridging of the interosseous region of the sacrum and ilium in 100% of specimens and ossification of the central interosseous region of the sacroiliac (SI) ligament in 60% of specimens. Central region ossification of the interosseous SI ligament and the presence of ridges and depressions over the opposing interosseous surfaces of the sacrum and ilium are features common to specimens that are in or beyond their sixth decade. These findings further support the contention that there is little to no movement available at this joint in older individuals.

Studies on the moss flora of the Bío-Bío Region of Chile: Part 3.

PubMed

Ireland, Robert R; Bellolio, Gilda; Larraín, Juan; Rodríguez, Roberto

2017-01-01

This is the final report on the moss flora of the Bío-Bío Region (Región VIII) in south-central Chile where collections were made in 2001-2003. Reported in this paper are one species new to South America, four species new to Chile and 16 species new to the Region. With these new additions the total number of taxa in the Bío-Bío Region is 343, corresponding to 331 species and 12 infraspecific taxa. A complete checklist of the mosses for all the provinces in the Region is presented.

Night Time Light Satellite Data for Evaluating the Socioeconomics in Central Asia

NASA Astrophysics Data System (ADS)

Li, S.; Zhang, T.; Yang, Z.; Li, X.; Xu, H.

2017-09-01

Using nighttime lights data combined with LandScan population counts and socioeconomic statistics, dynamic change was monitored in the social economy of the five countries in Central Asia, from 1993 to 2012. In addition, the spatial pattern of regional historical development was analyzed, using this data. The countries included in this study were Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan and Turkmenistan. The economic development in these five Central Asian countries, the movement of the economic center, the distribution of poor areas and the night light development index (NLDI) were studied at a relatively fine spatial scale. In addition, we studied the relationship between the per capita lighting and per capita GDP at the national scale, finding that the per capital lighting correlated with per capita GDP. The results of this study reflect the socioeconomic development of Central Asia but more importantly, show that nighttime light satellite images are an effective tool for monitoring spatial and temporal social economic parameters.

Monitoring Cloud-prone Complex Landscapes At Multiple Spatial Scales Using Medium And High Resolution Optical Data: A Case Study In Central Africa

NASA Astrophysics Data System (ADS)

Basnet, Bikash

Tracking land surface dynamics over cloud-prone areas with complex mountainous terrain and a landscape that is heterogeneous at a scale of approximately 10 m, is an important challenge in the remote sensing of tropical regions in developing nations, due to the small plot sizes. Persistent monitoring of natural resources in these regions at multiple spatial scales requires development of tools to identify emerging land cover transformation due to anthropogenic causes, such as agricultural expansion and climate change. Along with the cloud cover and obstructions by topographic distortions due to steep terrain, there are limitations to the accuracy of monitoring change using available historical satellite imagery, largely due to sparse data access and the lack of high quality ground truth for classifier training. One such complex region is the Lake Kivu region in Central Africa. This work addressed these problems to create an effective process for monitoring the Lake Kivu region located in Central Africa. The Lake Kivu region is a biodiversity hotspot with a complex and heterogeneous landscape and intensive agricultural development, where individual plot sizes are often at the scale of 10m. Procedures were developed that use optical data from satellite and aerial observations at multiple scales to tackle the monitoring challenges. First, a novel processing chain was developed to systematically monitor the spatio-temporal land cover dynamics of this region over the years 1988, 2001, and 2011 using Landsat data, complemented by ancillary data. Topographic compensation was performed on Landsat reflectances to avoid the strong illumination angle impacts and image compositing was used to compensate for frequent cloud cover and thus incomplete annual data availability in the archive. A systematic supervised classification, using the state-of-the-art machine learning classifier Random Forest, was applied to the composite Landsat imagery to obtain land cover thematic maps with overall accuracies of 90% and higher. Subsequent change analysis between these years found extensive conversions of the natural environment as a result of human related activities. The gross forest cover loss for 1988--2001 and 2001--2011 periods was 216.4 and 130.5 thousand hectares, respectively, signifying significant deforestation in the period of civil war and a relatively stable and lower deforestation rate later, possibly due to conservation and reforestation efforts in the region. The other dominant land cover changes in the region were aggressive subsistence farming and urban expansion displacing natural vegetation and arable lands. Despite limited data availability, this study fills the gap of much needed detailed and updated land cover change information for this biologically important region of Central Africa. While useful on a regional scale, Landsat data can be inadequate for more detailed studies of land cover change. Based on an increasing availability of high resolution imagery and light detection and ranging (LiDAR) data from manned and unmanned aerial platforms (<1m resolution), a study was performed leading to a novel generic framework for land cover monitoring at fine spatial scales. The approach fuses high spatial resolution aerial imagery and LiDAR data to produce land cover maps with high spatial detail using object-based image analysis techniques. The classification framework was tested for a scene with both natural and cultural features and was found to be more than 90 percent accurate, sufficient for detailed land cover change studies.

QEEG Spectral and Coherence Assessment of Autistic Children in Three Different Experimental Conditions

ERIC Educational Resources Information Center

Machado, Calixto; Estévez, Mario; Leisman, Gerry; Melillo, Robert; Rodríguez, Rafael; DeFina, Phillip; Hernández, Adrián; Pérez-Nellar, Jesús; Naranjo, Rolando; Chinchilla, Mauricio; Garófalo, Nicolás; Vargas, José; Beltrán, Carlos

2015-01-01

We studied autistics by quantitative EEG spectral and coherence analysis during three experimental conditions: basal, watching a cartoon with audio (V-A), and with muted audio band (VwA). Significant reductions were found for the absolute power spectral density (PSD) in the central region for delta and theta, and in the posterior region for sigma…

Writing Placement and Proficiency Assessment Practices in Two Rural Two-Year Colleges

ERIC Educational Resources Information Center

Wise, Melody Anne

2013-01-01

This research is a dual-case study which specifically focuses on two rural two-year colleges in separate parts of the United States: one in the central Southern region, and the other in the Northeastern region. I wanted to focus on these colleges' writing placement and proficiency practices in relation to their respective missions and how they…

Age structure and expansion of pinon-juniper woodlands: a regional perspective in the Intermountain West

Treesearch

Richard F. Miller; Robin J. Tausch; E. Durant McArthur; Dustin D. Johnson; Stewart C. Sanderson

2008-01-01

Numerous studies have documented the expansion of woodlands in the Intermountain West; however, few have compared the chronology of expansion for woodlands across different geographic regions or determined the mix and extent of presettlement stands. We evaluated tree age structure and establishment for six woodlands in four ecological provinces in the central and...

Striking a Balance: Academic Advising and the Advisory Working Alliance with Adult Master's-Level Credential Candidates at Regional Campuses

ERIC Educational Resources Information Center

Saunders, Cindy Franklin

2012-01-01

Purpose: The purpose of this study was to describe the advising approaches and the training received by academic advisors to form an advisory working alliance with adult master's-level credential candidates in educator preparation programs at regional campuses in Southern and Central California. This advisory working alliance concept includes: (a)…

Seasonal and geographic variations in the incidence of asthma exacerbations in the United States.

PubMed

Gerhardsson de Verdier, M; Gustafson, Per; McCrae, Christopher; Edsbäcker, Staffan; Johnston, Neil

2017-10-01

Exacerbations drive the burden of asthma and lead to significant morbidity and consumption of health care resources. Many prior studies of the epidemiology of asthma exacerbations have relied upon data from hospital care. The objective of this study was to determine US patterns of geographic and seasonal variations of asthma exacerbations being defined as asthma episodes requiring hospital care and/or a prescription for oral steroid. The study was a retrospective observational cohort study using administrative claims data for insured individuals from the HealthCore Integrated Research Database, including around 43 million members in the United States. Analyses examined 3 age groups, 6-17, 18-64, and ≥65 years and four US regions, Northeast, Southeast, Central, and Western. Monthly rates of asthma exacerbations showed the greatest variation over the year in children, less so in adults and in the elderly. Clinically important differences in rates of asthma exacerbation were observed between regions with the Western Region having the lowest in all three age groups followed by the Northeast, Central, and Southeast regions. Peaks in children occurred in the early fall following troughs in the summer months, and peaks at year-end occurred in adults, particularly in those over 65 years. There is a striking seasonal variation in asthma exacerbations in the United States. Substantial differences between regions of the United States in asthma exacerbation rates cannot readily be explained and invite further investigation.

Central nervous system tumours profile at a referral center in the Brazilian Amazon region, 1997–2014

PubMed Central

Semblano, Aluízio Augusto Pereira; Moreira, Matheus Acácio; de Lemos, Manuela Nascimento; de Mello, Vanessa Jóia; Hamoy, Moisés; Nazareth Junior, Mario Hermes; Paschoal Junior, Fernando Mendes; Adami, Fernando

2017-01-01

Tumours of the Central Nervous System (CNS) are an important cause of mortality from cancer. Epidemiological data on neoplams affecting the CNS are scarce in Brazil, especially in the Amazon region. The study aims at describing the histopathological profile of CNS tumours cases at a high-complexity referral cancer center. This study has described a 17-year-series profile of CNS tumours, registered at a high-complexity referral cancer center in Pará state, from January 1997 until July 2014 in the Brazilian Amazon Region. Data was gathered from histopathology reports kept in the hospital’s cancer registry and 949 cases of CNS tumours were analyzed. The most common histopathology were neuroepithelial tumours (approx. 40%) and meningioma was the most frequent especific tumor histologic subtype (22.2%). Neuroepithelial tumours were more frequent in patients with ages ranging from less than a year to 19 years, whereas metastatic tumours were prevalent in patients over 40 years of age. It was not found temporal trends during the studied period. The knowledge of these tumours profile is valuable for the understanding of cancer epidemiology in the region, since its prevalence is currently underreported and more awareness on the disease is needed. PMID:28369089

Hyalomma anatolicum as the Main Infesting Tick in an Important Livestock Rearing Region, Central Area of Iran.

PubMed

Biglari, Peyvand; Bakhshi, Hasan; Chinikar, Sadegh; Belqeiszadeh, Hamid; Ghaffari, Masoud; Javaherizadeh, Siavash; Faghihi, Faezeh; Telmadarraiy, Zakkyeh

2018-05-01

This study was carried out to determine the infestation of domestic ruminants to ticks in an important livestock-rearing region, located in central part of Iran. Ticks were collected from cattle, sheep, and goats and then were identified with appropriate identification keys to species level in two different ecological regions of plains and mountain in 4 seasons in 2015. Totally 492 ticks from cattle, sheep, and goats in 34 herds were collected. Totally, 18.53% of domestic animals were infected by ticks. All ticks were belonged to family Ixodidae and classified into three genera and six species comprising Hyalomma anatolicum (38.83%) , Hy. Asiaticum (23.37%), Hy. marginatum (2.85%), Hy. sp. (3.45%), Rhipicephalus sanguineus (14.02%) and Haemaphysalis sulcata (10.98%). Sex ratio of the collected specimens showed 241 (48.99%) male, 219 (44.51%) female and 32 (6.5%) nymph. Studied area is important for production of livestock and dairy products. Annually, many livestock products are exported to other parts from this region; therefore, it is very important to identify the infection rate of tick-borne diseases as well as safety factors on livestock.

Duration of detection of anti-BmR1 IgG4 antibodies after mass-drug administration (MDA) in Sarawak, Malaysia.

PubMed

Noordin, R; Muhi, J; Md Idris, Z; Arifin, N; Kiyu, A

2012-03-01

The detection rates of brugian filariasis in three regions of Sarawak namely Central, North and South after three courses of mass drug administration (MDA) from year 2004 to 2006 was investigated. A recombinant BmR1 antigen-based IgG4 detection test, named Brugia Rapid and night blood smear for microfilaria (mf) detection were used. All three regions recorded a sharp fall in mf positive rates after a year post-MDA. Meanwhile Brugia Rapid positive rates declined more gradually to 3.8% and 5.6% of the pre-MDA levels in the Central and North regions, respectively. This study showed that in filariasis endemic areas in Sarawak, anti-filarial IgG4 antibodies to BmR1, as detected by the Brugia Rapid test, were positive for one to two years after mf disappearance.

THE EXTENT OF MINE DRAINAGE INTO STREAMS OF THE CENTRAL APPALACHIAN AND ROCKY MOUNTAIN REGIONS

EPA Science Inventory

Runoff and drainage from active and inactive mines are contaminating streams throughout the United States with acidic and metal contaminated waters and sediments. The extent of mining impacts on streams of the coal bearing region of the Central Appalachians and the metal bearing...

Source Sector and Region Contributions to BC and PM2.5 in Central Asia

EPA Science Inventory

Particulate matter (PM) mass concentrations, seasonal cycles, source sector and source region contributions in Central Asia (CA) are analyzed for the period April 2008-July 2009 using the STEM chemical transport model and modeled meteorology from the WRF model. Predicted AOD valu...

78 FR 45521 - Centralized Capacity Markets in Regional Transmission Organizations and Independent System...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

.... This conference is free of charge and open to the public. Commission members may participate in the..., supplement or substitute for typical centralized capacity market design elements in order to meet current and... Capacity Markets in Regional Transmission Organizations and Independent System Operators:Supplemental...

Integration Plan for the Mid-Region Council of Governments : Central New Mexico Climate Change Scenario Planning Project.

DOT National Transportation Integrated Search

2015-04-01

This Integration Plan for the Central New Mexico Climate Change Scenario Planning Project (CCSP) provides useful information on strategies that the Mid-Region Council of Governments (MRCOG) and its partners can pursue over the next five years to adap...

Assessment of soil health in the central claypan region, Missouri

USDA-ARS?s Scientific Manuscript database

Assessment of soil health involves determining how well a soil is performing its biological, chemical, and physical functions relative to its inherent potential. Within the Central Claypan Region of Missouri, the Salt River Basin was selected as a benchmark watershed to assess long-term effects of c...

Lease hunting in the central hardwood region: an examination of tradeoffs

Treesearch

Stephen M. Bratkovich; Donald W. Floyd

1993-01-01

An examination of literature pertaining to lease (fee) hunting resulted in a description of tradeoffs for landowners, hunters, wildlife managers, and wildlife in the Central hardwood forest region. Landowner advantages associated with a lease hunting enterprise were better vandalism and trespass control, increased income, increased services, enhanced wildlife...

Characteristics of Fine Particulate Carbonaceous Aerosol at Two Remote Sites in Central Asia

EPA Science Inventory

Central Asia is a relatively understudied region of the world in terms of characterizing ambient particulate matter (PM) and quantifying source impacts of PM at receptor locations, although it is speculated to have an important role as a source region for long-range transport of ...

Forest statistics for the Hill Country of Ohio

Treesearch

The Forest Survey Organization. Central States Forest Experiment Station

1954-01-01

In this report forest-area and timber-volume statistics for South-Central, Southeastern, and East-Central Ohio (frontispiece) are shown separately. Regional boundaries were established for the purpose of grouping counties with similar forest, soil, geologic, or economic conditions. This report covers the unglaciated, hill region of the State.

A single base substitution in the coding region for neurophysin II associated with familial central diabetes insipidus.

PubMed Central

Ito, M; Mori, Y; Oiso, Y; Saito, H

1991-01-01

To elucidate the molecular mechanism of familial central diabetes insipidus (FDI), we sequenced the arginine vasopressin-neurophysin II (AVP-NPII) gene in 2 patients belonging to a pedigree that is consistent with an autosomal dominant mode of inheritance. 10 patients with idiopathic central diabetes insipidus (IDI) and 5 normals were also studied. The AVP-NPII gene, locating on chromosome 20, consists of three exons that encode putative signal peptide, AVP, NPII, and glycoprotein. Using polymerase chain reaction, fragments including the promoter region and all coding regions were amplified from genomic DNA and subjected to direct sequencing. Sequences of 10 patients with IDI were identical with those of normals, while in 2 patients with FDI, a single base substitution was detected in one of two alleles of the AVP-NPII gene, indicating they were heterozygotes for this mutation. It was a G----A transition at nucleotide position 1859 in the second exon, resulting in a substitution of Gly for Ser at amino acid position 57 in the NPII moiety. It was speculated that the mutated AVP-NPII precursor or the mutated NPII molecule, through their conformational changes, might be responsible for AVP deficiency. Images PMID:1840604

Study of the Seismic Cycle of large Earthquakes in central Peru: Lima Region

NASA Astrophysics Data System (ADS)

Norabuena, E. O.; Quiroz, W.; Dixon, T. H.

2009-12-01

Since historical times, the Peruvian subduction zone has been source of large and destructive earthquakes. The more damaging one occurred on May 30 1970 offshore Peru’s northern city of Chimbote with a death toll of 70,000 people and several hundred US million dollars in property damage. More recently, three contiguous plate interface segments in southern Peru completed their seismic cycle generating the 1996 Nazca (Mw 7.1), the 2001 Atico-Arequipa (Mw 8.4) and the 2007 Pisco (Mw 7.9) earthquakes. GPS measurements obtained between 1994-2001 by IGP-CIW an University of Miami-RSMAS on the central Andes of Peru and Bolivia were used to estimate their coseismic displacements and late stage of interseismic strain accumulation. However, we focus our interest in central Peru-Lima region, which with its about 9’000,000 inhabitants is located over a locked plate interface that has not broken with magnitude Mw 8 earthquakes since May 1940, September 1966 and October 1974. We use a network of 11 GPS monuments to estimate the interseismic velocity field, infer spatial variations of interplate coupling and its relation with the background seismicity of the region.

Mechanisms of insulin action on sympathetic nerve activity

NASA Technical Reports Server (NTRS)

Muntzel, Martin S.; Anderson, Erling A.; Johnson, Alan Kim; Mark, Allyn L.

1996-01-01

Insulin resistance and hyperinsulinemia may contribute to the development of arterial hypertension. Although insulin may elevate arterial pressure, in part, through activation of the sympathetic nervous system, the sites and mechanisms of insulin-induced sympathetic excitation remain uncertain. While sympathoexcitation during insulin may be mediated by the baroreflex, or by modulation of norepinephrine release from sympathetic nerve endings, it has been shown repeatedly that insulin increases sympathetic outflow by actions on the central nervous system. Previous studies employing norepinephrine turnover have suggested that insulin causes sympathoexcitation by acting in the hypothalamus. Recent experiments from our laboratory involving direct measurements of regional sympathetic nerve activity have provided further evidence that insulin acts in the central nervous system. For example, administration of insulin into the third cerebralventricle increased lumbar but not renal or adrenal sympathetic nerve activity in normotensive rats. Interestingly, this pattern of regional sympathetic nerve responses to central neural administration of insulin is similar to that seen with systemic administration of insulin. Further, lesions of the anteroventral third ventricle hypothalamic (AV3V) region abolished increases in sympathetic activity to systemic administration of insulin with euglycemic clamp, suggesting that AV3V-related structures are critical for insulin-induced elevations in sympathetic outflow.

Detection of Crimean-Congo hemorrhagic fever virus-specific IgG antibodies in ruminants residing in Central and Western Macedonia, Greece.

PubMed

Schuster, Isolde; Chaintoutis, Serafeim C; Dovas, Chrysostomos I; Groschup, Martin H; Mertens, Marc

2017-06-01

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus which causes lethal hemorrhagic fever in humans. Although, several reports regarding CCHFV antibody prevalence in humans exist in Greece, information about the current distribution is limited. The aim of the present study is to investigate the prevalence of CCHFV-specific IgG antibodies in cattle and sheep in Macedonia-Greece. The samplings were performed during spring 2013, in 5 regional units of Central Macedonia (Chalkidiki, Imathia, Kilkis, Pella and Thessaloniki) and in the 4 regional units of Western Macedonia (Grevena, Florina, Kastoria and Kozani). Specifically, sera from 538 cattle and 81 sheep underwent testing against CCHFV-specific IgG antibodies. Antiviral immune responses were observed in 31 cattle (6%, 95% CI: 4-8%) and in one sheep (1%, 95% CI: 0-8%). The total seroprevalence in the cattle sampled in Central Macedonia was 7% (28 out of 396, 95% CI: 5-10%). Within Central Macedonia, the highest seroprevalence was detected in Chalkidiki (38%, 95% CI: 23-56%), which was significantly higher (p<0.01) compared to the overall seroprevalence detected in cattle. In Western Macedonia, the total seroprevalence in cattle was 2% (3 out of 142, 95% CI: 1-7%). The 3 seropositive cattle were residing in the regional unit of Grevena. The one IgG-positive sheep serum was obtained from an animal residing in Thessaloniki. In this regional unit, the prevalence in sheep (2%, 95% CI: 0-10%) was much lower compared to the prevalence in cattle (12%, 95% CI: 6-22%), but significance was not achieved (p=0.03). The here presented seroepidemiological study demonstrates high transmission risk to human in specific geographical areas, which should be communicated to national and local public health authorities, so as to intensify preventive measures for public health protection. Copyright © 2017. Published by Elsevier GmbH.

Plate kinematics of the Afro-Arabian Rift System with emphasis on the Afar Depression, Ethiopia

NASA Astrophysics Data System (ADS)

Bottenberg, Helen Carrie

This work utilizes the Four-Dimensional Plates (4DPlates) software, and Differential Interferometric Synthetic Aperture Radar (DInSAR) to examine plate-scale, regional-scale and local-scale kinematics of the Afro-Arabian Rift System with emphasis on the Afar Depression in Ethiopia. First, the 4DPlates is used to restore the Red Sea, the Gulf of Aden, the Afar Depression and the Main Ethiopian Rift to development of a new model that adopts two poles of rotation for Arabia. Second, the 4DPlates is used to model regional-scale and local-scale kinematics within the Afar Depression. Most plate reconstruction models of the Afro-Arabian Rift System relies on considering the Afar Depression as a typical rift-rift-rift triple junction where the Arabian, Somali and Nubian (African) plates are separating by the Red Sea, the Gulf of Aden and the Main Ethiopian Rift suggesting the presence of "sharp and rigid" plate boundaries. However, at the regional-scale the Afar kinematics are more complex due to stepping of the Red Sea propagator and the Gulf of Aden propagator onto Afar as well as the presence of the Danakil, Ali Sabieh and East Central Block "micro-plates". This study incorporates the motion of these micro-plates into the regional-scale model and defined the plate boundary between the Arabian and the African plates within Afar as likely a diffused zone of extensional strain within the East Central Block. Third, DInSAR technology is used to create ascending and descending differential interferograms from the Envisat Advanced Synthetic Aperture Radar (ASAR) C-Band data for the East Central Block to image active crustal deformation related to extensional tectonics and volcanism. Results of the DInSAR study indicate no strong strain localization but rather a diffused pattern of deformation across the entire East Central Block.

Mapping Excitation in the Inner Regions of the Planetary Nebula NGC 5189 Using HST WFC3 Imaging

NASA Astrophysics Data System (ADS)

Danehkar, Ashkbiz; Karovska, Margarita; Maksym, W. Peter; Montez, Rodolfo, Jr.

2018-01-01

The planetary nebula (PN) NGC 5189 around a Wolf–Rayet [WO] central star demonstrates one of the most remarkable complex morphologies among PNe with many multiscale structures, showing evidence of multiple outbursts from an asymptotic giant branch (AGB) progenitor. In this study, we use multiwavelength Hubble Space Telescope Wide Field Camera 3 observations to study the morphology of the inner 0.3 pc × 0.2 pc region surrounding the central binary that appears to be a relic of a more recent outburst of the progenitor AGB star. We applied diagnostic diagrams based on emission-line ratios of Hα λ6563, [O III] λ5007, and [S II] λ λ 6716,6731 images to identify the location and morphology of low-ionization structures within the inner nebula. We distinguished two inner, low-ionization envelopes from the ionized gas, within a radius of 55 arcsec (∼0.15 pc) extending from the central star: a large envelope expanding toward the northeast, and its smaller counterpart envelope in the opposite direction toward the southwest of the nebula. These low-ionization envelopes are surrounded by a highly ionized gaseous environment. We believe that these low-ionization expanding envelopes are a result of a powerful outburst from the post-AGB star that created shocked wind regions as they propagate through the previously expelled material along a symmetric axis. Our diagnostic mapping using high-angular resolution line-emission imaging can provide a novel approach to detection of low-ionization regions in other PNe, especially those showing a complex multiscale morphology.

Using Brain Oscillations and Corticospinal Excitability to Understand and Predict Post-Stroke Motor Function

PubMed Central

Thibaut, Aurore; Simis, Marcel; Battistella, Linamara Rizzo; Fanciullacci, Chiara; Bertolucci, Federica; Huerta-Gutierrez, Rodrigo; Chisari, Carmelo; Fregni, Felipe

2017-01-01

What determines motor recovery in stroke is still unknown and finding markers that could predict and improve stroke recovery is a challenge. In this study, we aimed at understanding the neural mechanisms of motor function recovery after stroke using neurophysiological markers by means of cortical excitability (transcranial magnetic stimulation—TMS) and brain oscillations (electroencephalography—EEG). In this cross-sectional study, 55 subjects with chronic stroke (62 ± 14 yo, 17 women, 32 ± 42 months post-stroke) were recruited in two sites. We analyzed TMS measures (i.e., motor threshold—MT—of the affected and unaffected sides) and EEG variables (i.e., power spectrum in different frequency bands and different brain regions of the affected and unaffected hemispheres) and their correlation with motor impairment as measured by Fugl-Meyer. Multiple univariate and multivariate linear regression analyses were performed to identify the predictors of good motor function. A significant interaction effect of MT in the affected hemisphere and power in beta bandwidth over the central region for both affected and unaffected hemispheres was found. We identified that motor function positively correlates with beta rhythm over the central region of the unaffected hemisphere, while it negatively correlates with beta rhythm in the affected hemisphere. Our results suggest that cortical activity in the affected and unaffected hemisphere measured by EEG provides new insights on the association between high-frequency rhythms and motor impairment, highlighting the role of an excess of beta in the affected central cortical region in poor motor function in stroke recovery. PMID:28539912

Using Brain Oscillations and Corticospinal Excitability to Understand and Predict Post-Stroke Motor Function.

PubMed

Thibaut, Aurore; Simis, Marcel; Battistella, Linamara Rizzo; Fanciullacci, Chiara; Bertolucci, Federica; Huerta-Gutierrez, Rodrigo; Chisari, Carmelo; Fregni, Felipe

2017-01-01

What determines motor recovery in stroke is still unknown and finding markers that could predict and improve stroke recovery is a challenge. In this study, we aimed at understanding the neural mechanisms of motor function recovery after stroke using neurophysiological markers by means of cortical excitability (transcranial magnetic stimulation-TMS) and brain oscillations (electroencephalography-EEG). In this cross-sectional study, 55 subjects with chronic stroke (62 ± 14 yo, 17 women, 32 ± 42 months post-stroke) were recruited in two sites. We analyzed TMS measures (i.e., motor threshold-MT-of the affected and unaffected sides) and EEG variables (i.e., power spectrum in different frequency bands and different brain regions of the affected and unaffected hemispheres) and their correlation with motor impairment as measured by Fugl-Meyer. Multiple univariate and multivariate linear regression analyses were performed to identify the predictors of good motor function. A significant interaction effect of MT in the affected hemisphere and power in beta bandwidth over the central region for both affected and unaffected hemispheres was found. We identified that motor function positively correlates with beta rhythm over the central region of the unaffected hemisphere, while it negatively correlates with beta rhythm in the affected hemisphere. Our results suggest that cortical activity in the affected and unaffected hemisphere measured by EEG provides new insights on the association between high-frequency rhythms and motor impairment, highlighting the role of an excess of beta in the affected central cortical region in poor motor function in stroke recovery.

Islands within an island: Population genetic structure of the endemic Sardinian newt, Euproctus platycephalus.

PubMed

Ball, Sarah E; Bovero, Stefano; Sotgiu, Giuseppe; Tessa, Giulia; Angelini, Claudio; Bielby, Jon; Durrant, Christopher; Favelli, Marco; Gazzaniga, Enrico; Garner, Trenton W J

2017-02-01

The identification of historic and contemporary barriers to dispersal is central to the conservation of endangered amphibians, but may be hindered by their complex life history and elusive nature. The complementary information generated by mitochondrial (mtDNA) and microsatellite markers generates a valuable tool in elucidating population structure and the impact of habitat fragmentation. We applied this approach to the study of an endangered montane newt, Euproctus platycephalus . Endemic to the Mediterranean island of Sardinia, it is threatened by anthropogenic activity, disease, and climate change. We have demonstrated a clear hierarchy of structure across genetically divergent and spatially distinct subpopulations. Divergence between three main mountain regions dominated genetic partitioning with both markers. Mitochondrial phylogeography revealed a deep division dating to ca. 1 million years ago (Mya), isolating the northern region, and further differentiation between the central and southern regions ca. 0.5 Mya, suggesting an association with Pleistocene severe glacial oscillations. Our findings are consistent with a model of southward range expansion during glacial periods, with postglacial range retraction to montane habitat and subsequent genetic isolation. Microsatellite markers revealed further strong population structure, demonstrating significant divergence within the central region, and partial differentiation within the south. The northern population showed reduced genetic diversity. Discordance between mitochondrial and microsatellite markers at this scale indicated a further complexity of population structure, in keeping with male-biased dispersal and female philopatry. Our study underscores the need to elucidate cryptic population structure in the ecology and conservation strategies for endangered island-restricted amphibians, especially in the context of disease and climate change.