Offering Global Collaboration Services beyond CERN and HEP

NASA Astrophysics Data System (ADS)

Fernandes, J.; Ferreira, P.; Baron, T.

2015-12-01

The CERN IT department has built over the years a performant and integrated ecosystem of collaboration tools, from videoconference and webcast services to event management software. These services have been designed and evolved in very close collaboration with the various communities surrounding the laboratory and have been massively adopted by CERN users. To cope with this very heavy usage, global infrastructures have been deployed which take full advantage of CERN's international and global nature. If these services and tools are instrumental in enabling the worldwide collaboration which generates major HEP breakthroughs, they would certainly also benefit other sectors of science in which globalization has already taken place. Some of these services are driven by commercial software (Vidyo or Wowza for example), some others have been developed internally and have already been made available to the world as Open Source Software in line with CERN's spirit and mission. Indico for example is now installed in 100+ institutes worldwide. But providing the software is often not enough and institutes, collaborations and project teams do not always possess the expertise, or human or material resources that are needed to set up and maintain such services. Regional and national institutions have to answer needs, which are growingly global and often contradict their operational capabilities or organizational mandate and so are looking at existing worldwide service offers such as CERN's. We believe that the accumulated experience obtained through the operation of a large scale worldwide collaboration service combined with CERN's global network and its recently- deployed Agile Infrastructure would allow the Organization to set up and operate collaborative services, such as Indico and Vidyo, at a much larger scale and on behalf of worldwide research and education institutions and thus answer these pressing demands while optimizing resources at a global level. Such services would

104th LHCC Meeting AGENDA OPEN Session

ScienceCinema

Bailey, Roger

2018-06-20

LHC Machine Status Report LHCC, November 2010. LHCC-2010-016 LHCC-A-104 OPEN Session on Wednesday, 17 November from 9h00 to 13h00 in Main Auditorium - All CERN staff and Users are welcome to attend Open Session - LIVE WEBCAST.

Center Director Bridges opens Super Safety and Health Day at KSC.

NASA Technical Reports Server (NTRS)

1999-01-01

Center Director Roy Bridges opens the second Super Safety and Health Day at Kennedy Space Center, an entire day when most normal work activities are suspended to allow personnel to attend safety- and health-related activities. The theme, 'Safety and Health Go Hand in Hand,' emphasized KSC's commitment to place the safety and health of the public, astronauts, employees and space- related resources first and foremost. Events included a keynote address, a panel session about related issues, vendor exhibits, and safety training in work groups. The keynote address and panel session were also broadcast internally over NASA television.

Open University

ScienceCinema

None

2018-05-25

Michel Pentz was born in South Africa and came to CERN in 1957 as a physicist and president of the Association of Personnel. He is also the founder of the Antiapartheid Movement in Geneva and helped found the Open University in Great Britain. He speaks about pedagogical, cultural and national contexts in which the method can be applied.

Signature CERN-URSS

ScienceCinema

None

2017-12-09

Le DG W.Jentschke souhaite la bienvenue à l'assemblée et aux invités pour la signature du protocole entre le Cern et l'URSS qui est un événement important. C'est en 1955 que 55 visiteurs soviétiques ont visité le Cern pour la première fois. Le premier DG au Cern, F.Bloch, et Mons.Amaldi sont aussi présents. Tandis que le discours anglais de W.Jentschke est traduit en russe, le discours russe de Mons.Morozov est traduit en anglais.

Commissioning the CERN IT Agile Infrastructure with experiment workloads

NASA Astrophysics Data System (ADS)

Medrano Llamas, Ramón; Harald Barreiro Megino, Fernando; Kucharczyk, Katarzyna; Kamil Denis, Marek; Cinquilli, Mattia

2014-06-01

In order to ease the management of their infrastructure, most of the WLCG sites are adopting cloud based strategies. In the case of CERN, the Tier 0 of the WLCG, is completely restructuring the resource and configuration management of their computing center under the codename Agile Infrastructure. Its goal is to manage 15,000 Virtual Machines by means of an OpenStack middleware in order to unify all the resources in CERN's two datacenters: the one placed in Meyrin and the new on in Wigner, Hungary. During the commissioning of this infrastructure, CERN IT is offering an attractive amount of computing resources to the experiments (800 cores for ATLAS and CMS) through a private cloud interface. ATLAS and CMS have joined forces to exploit them by running stress tests and simulation workloads since November 2012. This work will describe the experience of the first deployments of the current experiment workloads on the CERN private cloud testbed. The paper is organized as follows: the first section will explain the integration of the experiment workload management systems (WMS) with the cloud resources. The second section will revisit the performance and stress testing performed with HammerCloud in order to evaluate and compare the suitability for the experiment workloads. The third section will go deeper into the dynamic provisioning techniques, such as the use of the cloud APIs directly by the WMS. The paper finishes with a review of the conclusions and the challenges ahead.

Lung Function before and Two Days after Open-Heart Surgery.

PubMed

Urell, Charlotte; Westerdahl, Elisabeth; Hedenström, Hans; Janson, Christer; Emtner, Margareta

2012-01-01

Reduced lung volumes and atelectasis are common after open-heart surgery, and pronounced restrictive lung volume impairment has been found. The aim of this study was to investigate factors influencing lung volumes on the second postoperative day. Open-heart surgery patients (n = 107, 68 yrs, 80% male) performed spirometry both before surgery and on the second postoperative day. The factors influencing postoperative lung volumes and decrease in lung volumes were investigated with univariate and multivariate analyses. Associations between pain (measured by numeric rating scale) and decrease in postoperative lung volumes were calculated with Spearman rank correlation test. Lung volumes decreased by 50% and were less than 40% of the predictive values postoperatively. Patients with BMI >25 had lower postoperative inspiratory capacity (IC) (33 ± 14% pred.) than normal-weight patients (39 ± 15% pred.), (P = 0.04). More pain during mobilisation was associated with higher decreases in postoperative lung volumes (VC: r = 0.33, P = 0.001; FEV(1): r = 0.35, P ≤ 0.0001; IC: r = 0.25, P = 0.01). Patients with high BMI are a risk group for decreased postoperative lung volumes and should therefore receive extra attention during postoperative care. As pain is related to a larger decrease in postoperative lung volumes, optimal pain relief for the patients should be identified.

Lung Function before and Two Days after Open-Heart Surgery

PubMed Central

Urell, Charlotte; Westerdahl, Elisabeth; Hedenström, Hans; Janson, Christer; Emtner, Margareta

2012-01-01

Reduced lung volumes and atelectasis are common after open-heart surgery, and pronounced restrictive lung volume impairment has been found. The aim of this study was to investigate factors influencing lung volumes on the second postoperative day. Open-heart surgery patients (n = 107, 68 yrs, 80% male) performed spirometry both before surgery and on the second postoperative day. The factors influencing postoperative lung volumes and decrease in lung volumes were investigated with univariate and multivariate analyses. Associations between pain (measured by numeric rating scale) and decrease in postoperative lung volumes were calculated with Spearman rank correlation test. Lung volumes decreased by 50% and were less than 40% of the predictive values postoperatively. Patients with BMI >25 had lower postoperative inspiratory capacity (IC) (33 ± 14% pred.) than normal-weight patients (39 ± 15% pred.), (P = 0.04). More pain during mobilisation was associated with higher decreases in postoperative lung volumes (VC: r = 0.33, P = 0.001; FEV1: r = 0.35, P ≤ 0.0001; IC: r = 0.25, P = 0.01). Patients with high BMI are a risk group for decreased postoperative lung volumes and should therefore receive extra attention during postoperative care. As pain is related to a larger decrease in postoperative lung volumes, optimal pain relief for the patients should be identified. PMID:22924127

Endovascular or open repair strategy for ruptured abdominal aortic aneurysm: 30 day outcomes from IMPROVE randomised trial.

PubMed

Powell, Janet T; Sweeting, Michael J; Thompson, Matthew M; Ashleigh, Ray; Bell, Rachel; Gomes, Manuel; Greenhalgh, Roger M; Grieve, Richard; Heatley, Francine; Hinchliffe, Robert J; Thompson, Simon G; Ulug, Pinar

2014-01-13

To assess whether a strategy of endovascular repair (if aortic morphology is suitable, open repair if not) versus open repair reduces early mortality for patients with suspected ruptured abdominal aortic aneurysm. Randomised controlled trial. 30 vascular centres (29 UK, 1 Canadian), 2009-13. 613 eligible patients (480 men) with a clinical diagnosis of ruptured aneurysm. 316 patients were randomised to the endovascular strategy (275 confirmed ruptures, 174 anatomically suitable for endovascular repair) and 297 to open repair (261 confirmed ruptures). 30 day mortality, with 24 hour and in-hospital mortality, costs, and time and place of discharge as secondary outcomes. 30 day mortality was 35.4% (112/316) in the endovascular strategy group and 37.4% (111/297) in the open repair group: odds ratio 0.92 (95% confidence interval 0.66 to 1.28; P=0.62); odds ratio after adjustment for age, sex, and Hardman index 0.94 (0.67 to 1.33). Women may benefit more than men (interaction test P=0.02) from the endovascular strategy: odds ratio 0.44 (0.22 to 0.91) versus 1.18 (0.80 to 1.75). 30 day mortality for patients with confirmed rupture was 36.4% (100/275) in the endovascular strategy group and 40.6% (106/261) in the open repair group (P=0.31). More patients in the endovascular strategy than in the open repair group were discharged directly to home (189/201 (94%) v 141/183 (77%); P<0.001). Average 30 day costs were similar between the randomised groups, with an incremental cost saving for the endovascular strategy versus open repair of £1186 (€1420; $1939) (95% confidence interval -£625 to £2997). A strategy of endovascular repair was not associated with significant reduction in either 30 day mortality or cost. Longer term cost effectiveness evaluations are needed to assess the full effects of the endovascular strategy in both men and women. Current Controlled Trials ISRCTN48334791.

NEWS: A trip to CERN

NASA Astrophysics Data System (ADS)

Ellison, A. D.

2000-07-01

Two years ago John Kinchin and myself were lucky enough to attend the Goldsmith's particle physics course. As well as many interesting lectures and activities, this course included a visit to CERN. To most physics teachers CERN is Mecca, a hallowed place where gods manipulate and manufacture matter. The experience of being there was even better. Alison Wright was an enthusiastic and very knowledgeable host who ensured the visit went smoothly and we all learned a lot. While we were there, John and I discussed the possibility of bringing a party of A-level students to see real physics in action. In February of this year we managed it. 33 students from two schools, Boston Grammar School and Northampton School for Boys, and four staff left England and caught the 2 am ferry to France. Many hours and a few `short cuts' later we arrived at our hotel in St Genis, not far from CERN. The first day was spent sight-seeing in Lausanne and Geneva. The Olympic museum in Lausanne is well worth a visit. Unfortunately, the famous fountain in Geneva was turned off, but then you can't have everything. The following morning we turned up at CERN late due to the coach's brakes being iced up! We were met once again by Alison Wright who forgave us and introduced the visit by giving an excellent talk on CERN, its background and its reason for existing. At this point we met another member of our Goldsmith's course and his students so we joined forces once again. We then piled back into the coach to re-cross the border and visit ALEPH. ALEPH is a monster of a detector 150 m below ground. We divided into four groups, each with a very able and knowledgeable guide, and toured the site. The size and scale of the detector are awesome and the students were suitably impressed. We repeated the speed of sound experiment of two years ago at the bottom of a 150 m concrete shaft (320 m s-1), posed for a group photo in front of the detector (figure 1) and returned to the main site for lunch in

April 1, 1967 : the opening day of the U.S. Department of Transportation.

DOT National Transportation Integrated Search

2017-01-01

On April 1, 1967, the U.S. Department of Transportation (USDOT) opened and began operations in Washington, DC. This poster is a story map of that day. A story map is a visualization tool that organizes text, maps, photos, and multimedia content to te...

PREFACE: Lectures from the CERN Winter School on Strings, Supergravity and Gauge Theories, CERN, 9-13 February 2009 Lectures from the CERN Winter School on Strings, Supergravity and Gauge Theories, CERN, 9-13 February 2009

NASA Astrophysics Data System (ADS)

Uranga, A. M.

2009-11-01

This special section is devoted to the proceedings of the conference `Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland 9-13 February 2009. This event is part of a yearly series of scientific schools, which represents a well established tradition. Previous events have been held at SISSA, in Trieste, Italy, in February 2005 and at CERN in January 2006, January 2007 and January 2008, and were funded by the European Mobility Research and Training Network `Constituents, Fundamental Forces and Symmetries of the Universe'. The next event will take place again at CERN, in January 2010. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of several general lectures of four hours each, whose notes are published in this special section, and six working group discussion sessions, focused on specific topics of the network research program. It was well attended by over 200 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress, and to the open problems, in string theory. One of the most active areas in string theory in recent years has been the AdS/CFT or gauge/gravity correspondence, which proposes the complete equivalence of string theory on (asymptotically) anti de Sitter spacetimes with certain quantum (gauge) field theories. The duality has recently been applied to understanding the hydrodynamical properties of a hot plasma in gauge theories (like the quark-gluon plasma created in heavy ion collisions at the RHIC experiment at Brookhaven, and soon at the LHC at CERN) in terms of a dual gravitational AdS theory in the presence of a black hole. These developments were reviewed in the lecture notes by M Rangamani. In addition, the AdS/CFT duality has been proposed as a tool to study interesting physical properties in other

48 CFR 22.1014 - Delay over 60 days in bid opening or commencement of work.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Delay over 60 days in bid... ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Service Contract Act of 1965, as Amended 22.1014 Delay over 60 days in bid opening or commencement of work. If a...

CERN welcomes new members

NASA Astrophysics Data System (ADS)

2017-08-01

Lithuania is on course to become an associate member of CERN, pending final approval by the Lithuanian parliament. Associate membership will allow representatives of the Baltic nation to take part in meetings of the CERN Council, which oversees the Geneva-based physics lab.

Open versus robot-assisted radical cystectomy: 30-day perioperative comparison and predictors for cost-to-patient, complication, and readmission.

PubMed

Flamiatos, Jason F; Chen, Yiyi; Lambert, William E; Martinez Acevedo, Ann; Becker, Thomas M; Bash, Jasper C; Amling, Christopher L

2018-06-08

The objectives of this study are to evaluate if robotic cystectomy demonstrates reduced complications, readmissions, and cost-to-patient compared to open approach 30-day post-operatively, and to identify predictors of complication, readmission, and cost-to-patient. This retrospective cohort study analyzed 249 patients who underwent open (n = 149) or robotic (n = 100) cystectomy from 2009 to 2015 at our institution. Outcomes included 30-day post-operative complication, readmission, and cost-to-patient charges. We used modified Clavien-Dindo/MSKCC classifications. Multivariable logistic and linear regression models were used to evaluate associations to outcomes and to build predictive models. Patient, clinical, and surgical characteristics differed by open and robotic groups, respectively, only for estimated blood loss (median: 600 versus 150 cc, p < 0.01), operative time (mean: 6.19 versus 6.85 h, p < 0.01), and length of stay (median: 7 versus 5 days, p < 0.01). Complication: frequency of patients with at least one 30-day complication was 85% compared to 66% (p < 0.01). Minor gastrointestinal and bleeding complications were increased in the open group (50% versus 41%, p = 0.01; 52% versus 11%, p < 0.01, respectively). Fifty percent of patients required blood transfusion in open compared to 11% (p < 0.01). Patients in the open group experienced more major complications (19% versus 10%, p = 0.04). Robotic approach was a predictor for fewer complications (OR 0.44, 95% CI 0.20-0.99, p = 0.049). Readmission: no significant difference in number of patients readmitted was found. Cost-to-patient: Robotic approach predicted an 18% reduction in total cost-to-patient compared to open approach (p < 0.01). Robotic cystectomy demonstrated reduced total cost-to-patient when taking into account all 30-day post-operative services with fewer complications compared to open cystectomy.

US SPACE CAMP CALIFORNIA - DAY CAMP GRAND OPENING WITH KEVIN JONES (WHISMAN SCHOOL) AND LUCRETIA

NASA Technical Reports Server (NTRS)

1996-01-01

US SPACE CAMP CALIFORNIA - DAY CAMP GRAND OPENING WITH KEVIN JONES (WHISMAN SCHOOL) AND LUCRETIA SUTHERLIN (MCNAIR SCHOOL). AMES SPONSORED STUDENTS AND RACHAEL QUIRING (STAFF) - AUTOGRAPH SIGNING BY Astronaut Wally Schirra

Introduction to CERN

ScienceCinema

Heuer, R.-D.

2018-02-19

Summer Student Lecture Programme Introduction. The mission of CERN; push back the frontiers of knowledge, e.g. the secrets of the Big Bang...what was the matter like within the first moments of the Universe's existence? You have to develop new technologies for accelerators and detectors (also information technology--the Web and the GRID and medicine--diagnosis and therapy). There are three key technology areas at CERN; accelerating, particle detection, large-scale computing.

Going for (Nano)Gold: A University Open Day Experiment for Year 13 Students

ERIC Educational Resources Information Center

Baker, Christopher; Patel, Bhavik Ani; Cragg, Alexander S.; Cragg, Peter J.

2013-01-01

Open day activities rarely give applicants a real sense of the practical and intellectual work that goes on in university chemistry departments. We devised an experiment for year 13 (age 17-18) students based on the size-dependent colours of gold nanoparticles and linked this to current research in diagnostic medicine. The experience was designed…

Helix Nebula and CERN: A Symbiotic approach to exploiting commercial clouds

NASA Astrophysics Data System (ADS)

Barreiro Megino, Fernando H.; Jones, Robert; Kucharczyk, Katarzyna; Medrano Llamas, Ramón; van der Ster, Daniel

2014-06-01

The recent paradigm shift toward cloud computing in IT, and general interest in "Big Data" in particular, have demonstrated that the computing requirements of HEP are no longer globally unique. Indeed, the CERN IT department and LHC experiments have already made significant R&D investments in delivering and exploiting cloud computing resources. While a number of technical evaluations of interesting commercial offerings from global IT enterprises have been performed by various physics labs, further technical, security, sociological, and legal issues need to be address before their large-scale adoption by the research community can be envisaged. Helix Nebula - the Science Cloud is an initiative that explores these questions by joining the forces of three European research institutes (CERN, ESA and EMBL) with leading European commercial IT enterprises. The goals of Helix Nebula are to establish a cloud platform federating multiple commercial cloud providers, along with new business models, which can sustain the cloud marketplace for years to come. This contribution will summarize the participation of CERN in Helix Nebula. We will explain CERN's flagship use-case and the model used to integrate several cloud providers with an LHC experiment's workload management system. During the first proof of concept, this project contributed over 40.000 CPU-days of Monte Carlo production throughput to the ATLAS experiment with marginal manpower required. CERN's experience, together with that of ESA and EMBL, is providing a great insight into the cloud computing industry and highlighted several challenges that are being tackled in order to ease the export of the scientific workloads to the cloud environments.

Skylab (SL)-4 Astronauts - "Open House" Press Day - SL Mockup - MSC

NASA Image and Video Library

1972-01-20

S72-17512 (19 Jan. 1972) --- These three men are the crewmen for the first manned Skylab mission. They are astronaut Charles Conrad Jr., commander, standing left; scientist-astronaut Joseph P. Kerwin, seated; and astronaut Paul J. Weitz, pilot. They were photographed and interviewed during an "open house" press day in the realistic atmosphere of the Multiple Docking Adapter (MDA) trainer in the Mission Simulation and Training Facility at the Manned Spacecraft Center (MSC). The control and display panel for the Apollo Telescope Mount (ATM) is at right. Photo credit: NASA

Opening Our Doors: Taking Public Library Service to Preschool and Day-Care Facilities.

ERIC Educational Resources Information Center

Harris, Sally

The Opening Our Doors Project of the Pioneer Library System of Norman, Oklahoma takes public library service to preschool and day care facilities by means of learning kits housed in tote bags. The sturdy, zippered tote bags are full of books, games, toys, learning folders, and so forth. There is a tote bag for each of 75 different topics. Topics…

PaaS for web applications with OpenShift Origin

NASA Astrophysics Data System (ADS)

Lossent, A.; Rodriguez Peon, A.; Wagner, A.

2017-10-01

The CERN Web Frameworks team has deployed OpenShift Origin to facilitate deployment of web applications and to improving efficiency in terms of computing resource usage. OpenShift leverages Docker containers and Kubernetes orchestration to provide a Platform-as-a-service solution oriented for web applications. We will review use cases and how OpenShift was integrated with other services such as source control, web site management and authentication services.

New directions in the CernVM file system

NASA Astrophysics Data System (ADS)

Blomer, Jakob; Buncic, Predrag; Ganis, Gerardo; Hardi, Nikola; Meusel, Rene; Popescu, Radu

2017-10-01

The CernVM File System today is commonly used to host and distribute application software stacks. In addition to this core task, recent developments expand the scope of the file system into two new areas. Firstly, CernVM-FS emerges as a good match for container engines to distribute the container image contents. Compared to native container image distribution (e.g. through the “Docker registry”), CernVM-FS massively reduces the network traffic for image distribution. This has been shown, for instance, by a prototype integration of CernVM-FS into Mesos developed by Mesosphere, Inc. We present a path for a smooth integration of CernVM-FS and Docker. Secondly, CernVM-FS recently raised new interest as an option for the distribution of experiment conditions data. Here, the focus is on improved versioning capabilities of CernVM-FS that allows to link the conditions data of a run period to the state of a CernVM-FS repository. Lastly, CernVM-FS has been extended to provide a name space for physics data for the LIGO and CMS collaborations. Searching through a data namespace is often done by a central, experiment specific database service. A name space on CernVM-FS can particularly benefit from an existing, scalable infrastructure and from the POSIX file system interface.

EFQPSK Versus CERN: A Comparative Study

NASA Technical Reports Server (NTRS)

Borah, Deva K.; Horan, Stephen

2001-01-01

This report presents a comparative study on Enhanced Feher's Quadrature Phase Shift Keying (EFQPSK) and Constrained Envelope Root Nyquist (CERN) techniques. These two techniques have been developed in recent times to provide high spectral and power efficiencies under nonlinear amplifier environment. The purpose of this study is to gain insights into these techniques and to help system planners and designers with an appropriate set of guidelines for using these techniques. The comparative study presented in this report relies on effective simulation models and procedures. Therefore, a significant part of this report is devoted to understanding the mathematical and simulation models of the techniques and their set-up procedures. In particular, mathematical models of EFQPSK and CERN, effects of the sampling rate in discrete time signal representation, and modeling of nonlinear amplifiers and predistorters have been considered in detail. The results of this study show that both EFQPSK and CERN signals provide spectrally efficient communications compared to filtered conventional linear modulation techniques when a nonlinear power amplifier is used. However, there are important differences. The spectral efficiency of CERN signals, with a small amount of input backoff, is significantly better than that of EFQPSK signals if the nonlinear amplifier is an ideal clipper. However, to achieve such spectral efficiencies with a practical nonlinear amplifier, CERN processing requires a predistorter which effectively translates the amplifier's characteristics close to those of an ideal clipper. Thus, the spectral performance of CERN signals strongly depends on the predistorter. EFQPSK signals, on the other hand, do not need such predistorters since their spectra are almost unaffected by the nonlinear amplifier, Ibis report discusses several receiver structures for EFQPSK signals. It is observed that optimal receiver structures can be realized for both coded and uncoded EFQPSK

A possible biomedical facility at the European Organization for Nuclear Research (CERN).

PubMed

Dosanjh, M; Jones, B; Myers, S

2013-05-01

A well-attended meeting, called "Brainstorming discussion for a possible biomedical facility at CERN", was held by the European Organization for Nuclear Research (CERN) at the European Laboratory for Particle Physics on 25 June 2012. This was concerned with adapting an existing, but little used, 78-m circumference CERN synchrotron to deliver a wide range of ion species, preferably from protons to at least neon ions, with beam specifications that match existing clinical facilities. The potential extensive research portfolio discussed included beam ballistics in humanoid phantoms, advanced dosimetry, remote imaging techniques and technical developments in beam delivery, including gantry design. In addition, a modern laboratory for biomedical characterisation of these beams would allow important radiobiological studies, such as relative biological effectiveness, in a dedicated facility with standardisation of experimental conditions and biological end points. A control photon and electron beam would be required nearby for relative biological effectiveness comparisons. Research beam time availability would far exceed that at other facilities throughout the world. This would allow more rapid progress in several biomedical areas, such as in charged hadron therapy of cancer, radioisotope production and radioprotection. The ethos of CERN, in terms of open access, peer-reviewed projects and governance has been so successful for High Energy Physics that application of the same to biomedicine would attract high-quality research, with possible contributions from Europe and beyond, along with potential new funding streams.

Vidyo@CERN: A Service Update

NASA Astrophysics Data System (ADS)

Fernandes, J.; Baron, T.

2015-12-01

We will present an overview of the current real-time video service offering for the LHC, in particular the operation of the CERN Vidyo service will be described in terms of consolidated performance and scale: The service is an increasingly critical part of the daily activity of the LHC collaborations, topping recently more than 50 million minutes of communication in one year, with peaks of up to 852 simultaneous connections. We will elaborate on the improvement of some front-end key features such as the integration with CERN Indico, or the enhancements of the Unified Client and also on new ones, released or in the pipeline, such as a new WebRTC client and CERN SSO/Federated SSO integration. An overview of future infrastructure improvements, such as virtualization techniques of Vidyo routers and geo-location mechanisms for load-balancing and optimum user distribution across the service infrastructure will also be discussed. The work done by CERN to improve the monitoring of its Vidyo network will also be presented and demoed. As a last point, we will touch the roadmap and strategy established by CERN and Vidyo with a clear objective of optimizing the service both on the end client and backend infrastructure to make it truly universal, to serve Global Science. To achieve those actions, the introduction of the multitenant concept to serve different communities is needed. This is one of the consequences of CERN's decision to offer the Vidyo service currently operated for the LHC, to other Sciences, Institutions and Virtual Organizations beyond HEP that might express interest for it.

101st LHCC Meeting AGENDA OPEN Sessions I and II

ScienceCinema

Wyatt, Terry

2018-06-19

OPEN Sessions I and II on Wednesday, 5 May from 9h00 to 16h30 in MAIN AUDITORIUM, CERN staff and Users are welcome to attend Open Sessions -LIVE WEBCAST. CLOSED Sessions on Wednesday, 5 May at 16h30 and Thursday, 6 May 8h15 in Conference room 60-6-015

101st LHCC Meeting AGENDA OPEN Sessions I and II

ScienceCinema

None

2017-12-09

OPEN Sessions I and II on Wednesday, 5 May from 9h00 to 16h30 in MAIN AUDITORIUM, CERN staff and Users are welcome to attend Open Sessions -LIVE WEBCAST. CLOSED Sessions on Wednesday, 5 May at 16h30 and Thursday, 6 May 8h15 in Conference room 60-6-015

Lecture archiving on a larger scale at the University of Michigan and CERN

NASA Astrophysics Data System (ADS)

Herr, Jeremy; Lougheed, Robert; Neal, Homer A.

2010-04-01

The ATLAS Collaboratory Project at the University of Michigan has been a leader in the area of collaborative tools since 1999. Its activities include the development of standards, software and hardware tools for lecture archiving, and making recommendations for videoconferencing and remote teaching facilities. Starting in 2006 our group became involved in classroom recordings, and in early 2008 we spawned CARMA, a University-wide recording service. This service uses a new portable recording system that we developed. Capture, archiving and dissemination of rich multimedia content from lectures, tutorials and classes are increasingly widespread activities among universities and research institutes. A growing array of related commercial and open source technologies is becoming available, with several new products introduced in the last couple years. As the result of a new close partnership between U-M and CERN IT, a market survey of these products was conducted and a summary of the results are presented here. It is informing an ambitious effort in 2009 to equip many CERN rooms with automated lecture archiving systems, on a much larger scale than before. This new technology is being integrated with CERN's existing webcast, CDS, and Indico applications.

CERN alerter—RSS based system for information broadcast to all CERN offices

NASA Astrophysics Data System (ADS)

Otto, R.

2008-07-01

Nearly every large organization uses a tool to broadcast messages and information across the internal campus (messages like alerts announcing interruption in services or just information about upcoming events). These tools typically allow administrators (operators) to send 'targeted' messages which are sent only to specific groups of users or computers, e/g only those located in a specified building or connected to a particular computing service. CERN has a long history of such tools: CERNVMS's SPM_quotMESSAGE command, Zephyr [2] and the most recent the NICE Alerter based on the NNTP protocol. The NICE Alerter used on all Windows-based computers had to be phased out as a consequence of phasing out NNTP at CERN. The new solution to broadcast information messages on the CERN campus continues to provide the service based on cross-platform technologies, hence minimizing custom developments and relying on commercial software as much as possible. The new system, called CERN Alerter, is based on RSS (Really Simple Syndication) [9] for the transport protocol and uses Microsoft SharePoint as the backend for database and posting interface. The windows-based client relies on Internet Explorer 7.0 with custom code to trigger the window pop-ups and the notifications for new events. Linux and Mac OS X clients could also rely on any RSS readers to subscribe to targeted notifications. The paper covers the architecture and implementation aspects of the new system.

DNS load balancing in the CERN cloud

NASA Astrophysics Data System (ADS)

Reguero Naredo, Ignacio; Lobato Pardavila, Lorena

2017-10-01

Load Balancing is one of the technologies enabling deployment of large-scale applications on cloud resources. A DNS Load Balancer Daemon (LBD) has been developed at CERN as a cost-effective way to balance applications accepting DNS timing dynamics and not requiring persistence. It currently serves over 450 load-balanced aliases with two small VMs acting as master and slave. The aliases are mapped to DNS subdomains. These subdomains are managed with DDNS according to a load metric, which is collected from the alias member nodes with SNMP. During the last years, several improvements were brought to the software, for instance: support for IPv6, parallelization of the status requests, implementing the client in Python to allow for multiple aliases with differentiated states on the same machine or support for application state. The configuration of the Load Balancer is currently managed by a Puppet type. It discovers the alias member nodes and gets the alias definitions from the Ermis REST service. The Aiermis self-service GUI for the management of the LB aliases has been produced and is based on the Ermis service above that implements a form of Load Balancing as a Service (LBaaS). The Ermis REST API has authorisation based in Foreman hostgroups. The CERN DNS LBD is Open Software with Apache 2 license.

CERN and high energy physics, the grand picture

ScienceCinema

Heuer, Rolf-Dieter

2018-05-24

The lecture will touch on several topics, to illustrate the role of CERN in the present and future of high-energy physics: how does CERN work? What is the role of the scientific community, of bodies like Council and SPC, and of international cooperation, in the definition of CERN's scientific programme? What are the plans for the future of the LHC and of the non-LHC physics programme? What is the role of R&D; and technology transfer at CERN?

100th LHCC meeting AGENDA OPEN and CLOSED Sessions

ScienceCinema

None

2017-12-09

OPEN Sessions on Wednesday, 17 February at 8h30-13h00 and 18 February at 9h00-11h00 in MAIN AUDITORIUM, CERN staff and Users are welcome to attend Open Sessions - LIVE WEBCAST. CLOSED Sessions in Conference room 60-6-015 Wednesday 17 February at 14h00-19h00 and continued on Thursday, 18 February at 11h00-17h00.

25th Birthday Cern- Amphi

ScienceCinema

None

2017-12-09

Cérémonie du 25ème anniversaire du Cern avec 2 orateurs: le Prof.Weisskopf parle de la signification et le rôle du Cern et le Prof.Casimir(?) fait un exposé sur les rélations entre la science pure et la science appliquée et la "big science" (science légère)

CERN automatic audio-conference service

NASA Astrophysics Data System (ADS)

Sierra Moral, Rodrigo

2010-04-01

Scientists from all over the world need to collaborate with CERN on a daily basis. They must be able to communicate effectively on their joint projects at any time; as a result telephone conferences have become indispensable and widely used. Managed by 6 operators, CERN already has more than 20000 hours and 5700 audio-conferences per year. However, the traditional telephone based audio-conference system needed to be modernized in three ways. Firstly, to provide the participants with more autonomy in the organization of their conferences; secondly, to eliminate the constraints of manual intervention by operators; and thirdly, to integrate the audio-conferences into a collaborative working framework. The large number, and hence cost, of the conferences prohibited externalization and so the CERN telecommunications team drew up a specification to implement a new system. It was decided to use a new commercial collaborative audio-conference solution based on the SIP protocol. The system was tested as the first European pilot and several improvements (such as billing, security, redundancy...) were implemented based on CERN's recommendations. The new automatic conference system has been operational since the second half of 2006. It is very popular for the users and has doubled the number of conferences in the past two years.

Tonsillectomy in children and in adults: changes in practice following the opening of a day-surgery unit with dedicated operating room.

PubMed

Bartier, S; Gharzouli, I; Kiblut, N; Bendimered, H; Cloutier, L; Salvan, D

2018-05-30

To study the impact of the opening of a day-surgery unit on the practice of tonsillectomy in adults and children in the light of the experience of our department, and to compare complications between day-surgery and conventional admission. A retrospective review was conducted of all tonsillectomies performed since the opening of a dedicated day-surgery room, using the ENT and emergency department data-bases. Between October 2013 and December 2014, 179 tonsillectomies were performed (51 in adults, 128 in children), including 108 day-surgeries. Between 2012 and 2014, the number of tonsillectomies increased by 12.7%, with an 18.27% increase in children and stable adult rate. Within 1 year, day-surgery became predominant for children (73.19%) and equaled conventional admission for adults (47.22%). For almost all patients without same-day discharge, the reasons were organizational or due to malorientation (comorbidity, or unsuitable home environment). Day-case tonsillectomy in children showed a 30-day complications rate comparable to those reported in the literature (8.3% postoperative hemorrhage), with a higher rate in adults (35.3%). Onset of complications was at a mean 6 days in adults and 9 days in children; only 2 patients developed complications between 6 and 24hours postoperatively. The present study showed that opening a day-surgery unit led to changes in practice, with most tonsillectomies now performed on an outpatient basis, without increased complications, and notably immediate complications. Outpatient tonsillectomy thus seems to be a solution of choice compared to conventional admission, in terms of cost saving and of patient comfort, without sacrificing safety. The dedicated operating room facilitates scheduling and thereby increasing turnover by reducing wait time. Copyright © 2018. Published by Elsevier Masson SAS.

INTEGRATED OPERATIONAL DOSIMETRY SYSTEM AT CERN.

PubMed

Dumont, Gérald; Pedrosa, Fernando Baltasar Dos Santos; Carbonez, Pierre; Forkel-Wirth, Doris; Ninin, Pierre; Fuentes, Eloy Reguero; Roesler, Stefan; Vollaire, Joachim

2017-04-01

CERN, the European Organization for Nuclear Research, upgraded its operational dosimetry system in March 2013 to be prepared for the first Long Shutdown of CERN's facilities. The new system allows the immediate and automatic checking and recording of the dosimetry data before and after interventions in radiation areas. To facilitate the analysis of the data in context of CERN's approach to As Low As Reasonably Achievable (ALARA), this new system is interfaced to the Intervention Management Planning and Coordination Tool (IMPACT). IMPACT is a web-based application widely used in all CERN's accelerators and their associated technical infrastructures for the planning, the coordination and the approval of interventions (work permit principle). The coupling of the operational dosimetry database with the IMPACT repository allows a direct and almost immediate comparison of the actual dose with the estimations, in addition to enabling the configuration of alarm levels in the dosemeter in function of the intervention to be performed. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Skylab 2 crew during "open house" press day at Manned Spacecraft Center (MSC)

NASA Image and Video Library

1972-01-19

S72-17509 (19 Jan. 1972) --- These three men are the crewmen for the first manned Skylab mission. They are astronaut Charles Conrad Jr., commander, standing left; scientist-astronaut Joseph P. Kerwin, seated; and astronaut Paul J. Weitz, pilot. They were photographed and interviewed during an "open house" press day in the realistic atmosphere of the Multiple Docking Adapter (MDA) trainer in the Mission Simulation and Training Facility at the Manned Spacecraft Center (MSC). The control and display panel for the Apollo Telescope Mount (ATM) is at right. Photo credit: NASA

The significance of Cern

ScienceCinema

None

2017-12-09

Le Prof. V.Weisskopf, DG du Cern de 1961 à 1965, est né à Vienne, a fait ses études à Göttingen et a une carrière académique particulièrement riche. Il a travaillé à Berlin, Copenhague et Berlin et est parti aux Etats Unis pour participer au projet Manhattan et était Prof. au MTT jusqu'à 1960. Revenu en Europe, il a été DG du Cern et lui a donné l'impulsion que l'on sait.

A possible biomedical facility at the European Organization for Nuclear Research (CERN)

PubMed Central

Dosanjh, M; Myers, S

2013-01-01

A well-attended meeting, called “Brainstorming discussion for a possible biomedical facility at CERN”, was held by the European Organization for Nuclear Research (CERN) at the European Laboratory for Particle Physics on 25 June 2012. This was concerned with adapting an existing, but little used, 78-m circumference CERN synchrotron to deliver a wide range of ion species, preferably from protons to at least neon ions, with beam specifications that match existing clinical facilities. The potential extensive research portfolio discussed included beam ballistics in humanoid phantoms, advanced dosimetry, remote imaging techniques and technical developments in beam delivery, including gantry design. In addition, a modern laboratory for biomedical characterisation of these beams would allow important radiobiological studies, such as relative biological effectiveness, in a dedicated facility with standardisation of experimental conditions and biological end points. A control photon and electron beam would be required nearby for relative biological effectiveness comparisons. Research beam time availability would far exceed that at other facilities throughout the world. This would allow more rapid progress in several biomedical areas, such as in charged hadron therapy of cancer, radioisotope production and radioprotection. The ethos of CERN, in terms of open access, peer-reviewed projects and governance has been so successful for High Energy Physics that application of the same to biomedicine would attract high-quality research, with possible contributions from Europe and beyond, along with potential new funding streams. PMID:23549990

Benefits of pre-emptive analgesia by local infiltration at day-case general anaesthetic open inguinal hernioplasty.

PubMed

Radwan, R W; Gardner, A; Jayamanne, H; Stephenson, B M

2018-03-15

Introduction The open prosthetic repair of inguinal hernias under local anaesthesia (LA) is well established, with the concept of intraoperative 'pre-emptive analgesia' evolving so that patients are as comfortable as possible. We used a peri-incisional LA solution in patients undergoing day-case inguinal hernioplasty under general anaesthesia (GA) and recorded use of analgesia in the immediate postoperative period. Methods In this observational cohort study, 100 consecutive unselected men underwent open inguinal hernia repair as a day case. Of these, 75 underwent repair under GA and 25 with peri-incisional LA solution (equal mixture of 0.5% bupivacaine and 1% lignocaine with 1:200,000 adrenaline). Analgesia prescribed at induction, for maintenance and after cessation of anaesthesia was scored in accordance with the World Health Organization (WHO) analgesic ladder. Results The median age in the GA group was 59 years (range: 25-89 years) and in the GA+LA group, it was 62 years (range: 27-88 years). Of the 100 patients, 82 underwent a mesh plug repair by seven surgeons whereas 18 underwent a flat (Lichtenstein) mesh repair by two surgeons. WHO analgesic induction and postoperative scores were significantly lower in the GA+LA group (p=0.034 and p<0.001 respectively). There was also a significant difference in use of postoperative antiemetics (23% vs 0% in the GA only and GA+LA cohorts respectively, p=0.020). Six patients (8%) in the GA group failed day-case discharge criteria. Conclusions Patients undergoing contemporary day-case GA inguinal hernioplasty with pre-emptive LA solution infiltration require lower levels of postoperative opioid analgesia and antiemetics. These cases are less likely to fail discharge criteria for planned day surgery.

[Establishment of a microbiology laboratory open 365 days a year and its impact].

PubMed

Komori, Toshiaki; Fujita, Naohisa; Hirose, Yuri; Kimura, Takeshi; Kyotani, Noriko; Kurahashi, Satoko; Yamada, Yukiji; Ushiyama, Masaji; Yasumoto, Towa; Yuasa, Soh-Ichi

2009-12-01

The microbiology laboratory of our university hospital aims to provide accurate and rapid microbiological results and useful information for healthcare workers involved in both the treatment of infectious diseases and infection control. For this purpose, we have been running a microbiology laboratory open 365 days a year since 2005. Before starting this laboratory, we formulated both a precise procedural manual and educational program to increase the number of microbiological technologists from 4 to 8 persons and improve their skills. Moreover, we reviewed the reporting system. As a result, we could report positive blood cultures up to 1.4 days earlier than previously possible, and significantly improved the prognosis of MRSA bacteremia patients by the early treatment of anti-MRSA antimicrobials within 48 hours after positive blood culture. In addition, the rate of MRSA/Staphylococcus aureus decreased to 35.8%. It is essential for the treatment of infectious diseases and infection control to accept only appropriate specimens and report the results rapidly and accurately.

Service management at CERN with Service-Now

NASA Astrophysics Data System (ADS)

Toteva, Z.; Alvarez Alonso, R.; Alvarez Granda, E.; Cheimariou, M.-E.; Fedorko, I.; Hefferman, J.; Lemaitre, S.; Clavo, D. Martin; Martinez Pedreira, P.; Pera Mira, O.

2012-12-01

The Information Technology (IT) and the General Services (GS) departments at CERN have decided to combine their extensive experience in support for IT and non-IT services towards a common goal - to bring the services closer to the end user based on Information Technology Infrastructure Library (ITIL) best practice. The collaborative efforts have so far produced definitions for the incident and the request fulfilment processes which are based on a unique two-dimensional service catalogue that combines both the user and the support team views of all services. After an extensive evaluation of the available industrial solutions, Service-now was selected as the tool to implement the CERN Service-Management processes. The initial release of the tool provided an attractive web portal for the users and successfully implemented two basic ITIL processes; the incident management and the request fulfilment processes. It also integrated with the CERN personnel databases and the LHC GRID ticketing system. Subsequent releases continued to integrate with other third-party tools like the facility management systems of CERN as well as to implement new processes such as change management. Independently from those new development activities it was decided to simplify the request fulfilment process in order to achieve easier acceptance by the CERN user community. We believe that due to the high modularity of the Service-now tool, the parallel design of ITIL processes e.g., event management and non-ITIL processes, e.g., computer centre hardware management, will be easily achieved. This presentation will describe the experience that we have acquired and the techniques that were followed to achieve the CERN customization of the Service-Now tool.

Global atmospheric particle formation from CERN CLOUD measurements.

PubMed

Dunne, Eimear M; Gordon, Hamish; Kürten, Andreas; Almeida, João; Duplissy, Jonathan; Williamson, Christina; Ortega, Ismael K; Pringle, Kirsty J; Adamov, Alexey; Baltensperger, Urs; Barmet, Peter; Benduhn, Francois; Bianchi, Federico; Breitenlechner, Martin; Clarke, Antony; Curtius, Joachim; Dommen, Josef; Donahue, Neil M; Ehrhart, Sebastian; Flagan, Richard C; Franchin, Alessandro; Guida, Roberto; Hakala, Jani; Hansel, Armin; Heinritzi, Martin; Jokinen, Tuija; Kangasluoma, Juha; Kirkby, Jasper; Kulmala, Markku; Kupc, Agnieszka; Lawler, Michael J; Lehtipalo, Katrianne; Makhmutov, Vladimir; Mann, Graham; Mathot, Serge; Merikanto, Joonas; Miettinen, Pasi; Nenes, Athanasios; Onnela, Antti; Rap, Alexandru; Reddington, Carly L S; Riccobono, Francesco; Richards, Nigel A D; Rissanen, Matti P; Rondo, Linda; Sarnela, Nina; Schobesberger, Siegfried; Sengupta, Kamalika; Simon, Mario; Sipilä, Mikko; Smith, James N; Stozkhov, Yuri; Tomé, Antonio; Tröstl, Jasmin; Wagner, Paul E; Wimmer, Daniela; Winkler, Paul M; Worsnop, Douglas R; Carslaw, Kenneth S

2016-12-02

Fundamental questions remain about the origin of newly formed atmospheric aerosol particles because data from laboratory measurements have been insufficient to build global models. In contrast, gas-phase chemistry models have been based on laboratory kinetics measurements for decades. We built a global model of aerosol formation by using extensive laboratory measurements of rates of nucleation involving sulfuric acid, ammonia, ions, and organic compounds conducted in the CERN CLOUD (Cosmics Leaving Outdoor Droplets) chamber. The simulations and a comparison with atmospheric observations show that nearly all nucleation throughout the present-day atmosphere involves ammonia or biogenic organic compounds, in addition to sulfuric acid. A considerable fraction of nucleation involves ions, but the relatively weak dependence on ion concentrations indicates that for the processes studied, variations in cosmic ray intensity do not appreciably affect climate through nucleation in the present-day atmosphere. Copyright © 2016, American Association for the Advancement of Science.

Learning with the ATLAS Experiment at CERN

ERIC Educational Resources Information Center

Barnett, R. M.; Johansson, K. E.; Kourkoumelis, C.; Long, L.; Pequenao, J.; Reimers, C.; Watkins, P.

2012-01-01

With the start of the LHC, the new particle collider at CERN, the ATLAS experiment is also providing high-energy particle collisions for educational purposes. Several education projects--education scenarios--have been developed and tested on students and teachers in several European countries within the Learning with ATLAS@CERN project. These…

Update on CERN Search based on SharePoint 2013

NASA Astrophysics Data System (ADS)

Alvarez, E.; Fernandez, S.; Lossent, A.; Posada, I.; Silva, B.; Wagner, A.

2017-10-01

CERN’s enterprise Search solution “CERN Search” provides a central search solution for users and CERN service providers. A total of about 20 million public and protected documents from a wide range of document collections is indexed, including Indico, TWiki, Drupal, SharePoint, JACOW, E-group archives, EDMS, and CERN Web pages. In spring 2015, CERN Search was migrated to a new infrastructure based on SharePoint 2013. In the context of this upgrade, the document pre-processing and indexing process was redesigned and generalised. The new data feeding framework allows to profit from new functionality and it facilitates the long term maintenance of the system.

News UK public libraries offer walk-in access to research Atoms for Peace? The Atomic Weapons Establishment and UK universities Students present their research to academics: CERN@school Science in a suitcase: Marvin and Milo visit Ethiopia Inspiring telescopes A day for everyone teaching physics 2014 Forthcoming Events

NASA Astrophysics Data System (ADS)

2014-05-01

UK public libraries offer walk-in access to research Atoms for Peace? The Atomic Weapons Establishment and UK universities Students present their research to academics: CERN@school Science in a suitcase: Marvin and Milo visit Ethiopia Inspiring telescopes A day for everyone teaching physics 2014 Forthcoming Events

CERN IRRADIATION FACILITIES.

PubMed

Pozzi, Fabio; Garcia Alia, Ruben; Brugger, Markus; Carbonez, Pierre; Danzeca, Salvatore; Gkotse, Blerina; Richard Jaekel, Martin; Ravotti, Federico; Silari, Marco; Tali, Maris

2017-09-28

CERN provides unique irradiation facilities for applications in dosimetry, metrology, intercomparison of radiation protection devices, benchmark of Monte Carlo codes and radiation damage studies to electronics. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

CERN Collider, France-Switzerland

NASA Image and Video Library

2013-08-23

This image, acquired by NASA Terra spacecraft, is of the CERN Large Hadron Collider, the world largest and highest-energy particle accelerator laying beneath the French-Swiss border northwest of Geneva yellow circle.

CERN goes iconic

NASA Astrophysics Data System (ADS)

2017-06-01

There are more than 1800 emoji that can be sent and received in text messages and e-mails. Now, the CERN particle-physics lab near Geneva has got in on the act and released its own collection of 35 images that can be used by anyone with an Apple device.

Review of CERN Data Centre Infrastructure

NASA Astrophysics Data System (ADS)

Andrade, P.; Bell, T.; van Eldik, J.; McCance, G.; Panzer-Steindel, B.; Coelho dos Santos, M.; Traylen and, S.; Schwickerath, U.

2012-12-01

The CERN Data Centre is reviewing strategies for optimizing the use of the existing infrastructure and expanding to a new data centre by studying how other large sites are being operated. Over the past six months, CERN has been investigating modern and widely-used tools and procedures used for virtualisation, clouds and fabric management in order to reduce operational effort, increase agility and support unattended remote data centres. This paper gives the details on the project's motivations, current status and areas for future investigation.

Scale out databases for CERN use cases

NASA Astrophysics Data System (ADS)

Baranowski, Zbigniew; Grzybek, Maciej; Canali, Luca; Lanza Garcia, Daniel; Surdy, Kacper

2015-12-01

Data generation rates are expected to grow very fast for some database workloads going into LHC run 2 and beyond. In particular this is expected for data coming from controls, logging and monitoring systems. Storing, administering and accessing big data sets in a relational database system can quickly become a very hard technical challenge, as the size of the active data set and the number of concurrent users increase. Scale-out database technologies are a rapidly developing set of solutions for deploying and managing very large data warehouses on commodity hardware and with open source software. In this paper we will describe the architecture and tests on database systems based on Hadoop and the Cloudera Impala engine. We will discuss the results of our tests, including tests of data loading and integration with existing data sources and in particular with relational databases. We will report on query performance tests done with various data sets of interest at CERN, notably data from the accelerator log database.

openQ*D simulation code for QCD+QED

NASA Astrophysics Data System (ADS)

Campos, Isabel; Fritzsch, Patrick; Hansen, Martin; Krstić Marinković, Marina; Patella, Agostino; Ramos, Alberto; Tantalo, Nazario

2018-03-01

The openQ*D code for the simulation of QCD+QED with C* boundary conditions is presented. This code is based on openQCD-1.6, from which it inherits the core features that ensure its efficiency: the locally-deflated SAP-preconditioned GCR solver, the twisted-mass frequency splitting of the fermion action, the multilevel integrator, the 4th order OMF integrator, the SSE/AVX intrinsics, etc. The photon field is treated as fully dynamical and C* boundary conditions can be chosen in the spatial directions. We discuss the main features of openQ*D, and we show basic test results and performance analysis. An alpha version of this code is publicly available and can be downloaded from http://rcstar.web.cern.ch/.

Wolfgang Kummer at CERN

NASA Astrophysics Data System (ADS)

Schopper, Herwig

Wolfgang Kummer was not only a great theorist but also a man with a noble spirit and extensive education, based on a fascinating long-term Austrian cultural tradition. As an experimentalist I am not sufficiently knowledgeable to evaluate his contributions to theoretical physics - this will certainly be done by more competent scientists. Nevertheless I admired him for not only being attached to fundamental and abstract problems like quantum field theory, quantum gravity or black holes, but for his interest in down to earth questions like electron-proton scattering or the toponium mass. I got to know Wolfgang Kummer very well and appreciate his human qualities during his long attachment to CERN, in particular when he served as president of the CERN Council, the highest decision taking authority of this international research centre, from 1985 to 1987 falling into my term as Director-General…

First experience with the new .cern Top Level Domain

NASA Astrophysics Data System (ADS)

Alvarez, E.; Malo de Molina, M.; Salwerowicz, M.; Silva De Sousa, B.; Smith, T.; Wagner, A.

2017-10-01

In October 2015, CERN’s core website has been moved to a new address, http://home.cern, marking the launch of the brand new top-level domain .cern. In combination with a formal governance and registration policy, the IT infrastructure needed to be extended to accommodate the hosting of Web sites in this new top level domain. We will present the technical implementation in the framework of the CERN Web Services that allows to provide virtual hosting, a reverse proxy solution and that also includes the provisioning of SSL server certificates for secure communications.

Dissemination of CERN's Technology Transfer: Added Value from Regional Transfer Agents

ERIC Educational Resources Information Center

Hofer, Franz

2005-01-01

Technologies developed at CERN, the European Organization for Nuclear Research, are disseminated via a network of external technology transfer officers. Each of CERN's 20 member states has appointed at least one technology transfer officer to help establish links with CERN. This network has been in place since 2001 and early experiences indicate…

Open access for ALICE analysis based on virtualization technology

NASA Astrophysics Data System (ADS)

Buncic, P.; Gheata, M.; Schutz, Y.

2015-12-01

Open access is one of the important leverages for long-term data preservation for a HEP experiment. To guarantee the usability of data analysis tools beyond the experiment lifetime it is crucial that third party users from the scientific community have access to the data and associated software. The ALICE Collaboration has developed a layer of lightweight components built on top of virtualization technology to hide the complexity and details of the experiment-specific software. Users can perform basic analysis tasks within CernVM, a lightweight generic virtual machine, paired with an ALICE specific contextualization. Once the virtual machine is launched, a graphical user interface is automatically started without any additional configuration. This interface allows downloading the base ALICE analysis software and running a set of ALICE analysis modules. Currently the available tools include fully documented tutorials for ALICE analysis, such as the measurement of strange particle production or the nuclear modification factor in Pb-Pb collisions. The interface can be easily extended to include an arbitrary number of additional analysis modules. We present the current status of the tools used by ALICE through the CERN open access portal, and the plans for future extensions of this system.

Sharing scientific discovery globally: toward a CERN virtual visit service

NASA Astrophysics Data System (ADS)

Goldfarb, S.; Hatzifotiadou, D.; Lapka, M.; Papanestis, A.

2017-10-01

The installation of virtual visit services by the LHC collaborations began shortly after the first high-energy collisions were provided by the CERN accelerator in 2010. The experiments: ATLAS [1], CMS [2], LHCb [3], and ALICE [4] have all joined in this popular and effective method to bring the excitement of scientific exploration and discovery into classrooms and other public venues around the world. Their programmes, which use a combination of video conference, webcast, and video recording to communicate with remote audiences have already reached tens of thousands of viewers, and the demand only continues to grow. Other venues, such as the CERN Control Centre, are also considering similar permanent installations. We present a summary of the development of the various systems in use around CERN today, including the technology deployed and a variety of use cases. We then lay down the arguments for the creation of a CERN-wide service that would support these programmes in a more coherent and effective manner. Potential services include a central booking system and operational management similar to what is currently provided for the common CERN video conference facilities. Certain choices in technology could be made to support programmes based on popular tools including (but not limited to) Skype™ [5], Google Hangouts [6], Facebook Live [7], and Periscope [8]. Successful implementation of the project, which relies on close partnership between the experiments, CERN IT CDA [9], and CERN IR ECO [10], has the potential to reach an even larger, global audience, more effectively than ever before.

Kaon and open charm production in central lead-lead collisions at the CERN SPS

NASA Astrophysics Data System (ADS)

van Leeuwen, Marco

2003-05-01

This thesis describes the experimental study of hadronic systems with a very high energy density and temperature. From theoretical caluclations it is expected that hadronic matter undergoes a phase transition to a deconfined state at an energy density of about 1 GeV/fm^3 or a temperature of 170 MeV. The goal of the experiments is to observe the phase transition and study the properties of the deconfined state, the Quark Gluon Plasma (QGP). Two different measurements are described and the results are discussed. The first measurement concerns the momentum distributions and total yields of kaons in lead-lead collisions at 40, 80 and 158 AGeV beam energy. Kaons are the most abundant carrier of the relatively heavy strange quarks and their production is expected to be sensitive to the energy density and the state of matter early in the collision. The second measurement is a search for the production of mesons which carry the even heavier charm quark, at the highest beam energy. The measurements have been performed with the NA49 detector at the SPS accelerator at CERN. The main detector elements are four Time Projection Chambers (TPCs), which record the trajectories of a large fraction of the final state particles to determine the charge and the momentum of each particle. In addition, the measurement of the ionisation energy loss dE/dx in the TPCs allows to identify pions, kaons and protons. Additional detectors provide a measurement of the time-of-flight in a limited acceptance. Combining the time-of-flight and dE/dx measurements greatly improves the separation of the different particle species. The kaon momentum distributions as presented in this thesis have been determined using the dE/dx measurement in the TPCs. The time-of-flight information is used for a detailed study of the peak shape of the dE/dx measurement. The resulting kaon spectra and total yields provide strong indications that interactions between produced particles or even thermalisation play an

Temporary crate opening procedure affects immediate post-opening piglet mortality and sow behaviour.

PubMed

King, R L; Baxter, E M; Matheson, S M; Edwards, S A

2018-05-07

Producers are interested in utilising farrowing systems with reduced confinement to improve sow welfare. However, concerns of increased mortality may limit commercial uptake. Temporary confinement systems utilise a standard crate which is opened 3 to 7 days postpartum, providing protection for neonatal piglets at their most vulnerable age and later increased freedom of movement for sows. However, there is anecdotal evidence that piglet mortality increases immediately after the temporary crate is opened. The current study aims were to determine if piglet mortality increases post-opening, to trial different opening techniques to reduce post-opening piglet mortality and to identify how the different opening techniques influence sow behaviour. Three opening treatments were implemented across 416 sows: two involved opening crates individually within each farrowing house when each litter reached 7 days of age, in either the morning or afternoon (AM or PM), with a control of the standard method used on the farm to open all crates in each farrowing house simultaneously once the average litter age reached 7 days (ALL). Behavioural observations were performed on five sows from each treatment during the 6 h after crate opening, and during the same 6 h period on the previous and subsequent days. Across all treatments, piglet mortality was significantly higher in the post-opening than pre-opening period (P<0.0005). Between opening treatments, there were significant differences in piglet mortality during the 2 days after crate opening (P<0.05), whilst piglet mortality also tended to differ from crate opening until weaning (P=0.052), being highest in ALL and lowest in PM. Only sows in the PM treatment showed no increase in standing behaviour but did show an increased number of potentially dangerous posture changes after crate opening (P=0.01), which may be partly attributed to the temporal difference in observation periods. Sow behaviour only differed between AM and ALL on the

History of Cern

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2007-12-20

Cérémonie à l'occasion de l'apparition du premier volume du livre sur l'histoire du Cern, avec plusieurs personnes présentes qui jouaient un rôle important dans cette organisation européenne couronnée de succès grâce à l'esprit des membres fondateurs qui est et restera essentiel

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-15

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network Constituents, Fundamental Forces and Symmetries of the Universe. The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva.

Evaluation of acute tacrine treatment on passive-avoidance response, open-field behavior, and toxicity in 17- and 30-day-old mice.

PubMed

Pan, S Y; Han, Y F; Yu, Z L; Yang, R; Dong, H; Ko, K M

2006-09-01

The potential of tacrine in altering cognitive/behavioral function as well as in causing toxicity was evaluated in mice of 17 and 30 days of age. Cognitive and behavioral studies were performed using a step-through passive avoidance task and a habituation open-field test with a 24-h retention interval. Tacrine was subcutaneously injected (1.25-80 micro mol/kg) 30 min prior to the first session of both tests. During the training session in step-through task, tacrine treatment dose-dependently decreased the number of footshocks, with IC(50) values being 7.8 and 23.3 micro mol/kg in 17- and 30-day-old mice, respectively. Treatment with tacrine at a low dose (5 micro mol/kg) significantly prolonged the retention latency in 17-day-old mice only, but it shortened the retention latency at high doses of 20 and 40 micro mol/kg in 17- and 30-day-old, respectively. During the acquisition session in the open-field test, tacrine treatment dose-dependently decreased the locomotor activity in 17- and 30-day-old mice, with IC(50) values being 15.1 and 24.7 micro mol/kg, respectively. High doses of tacrine invariably increased the locomotor activity during the recall session. Tacrine treatment at a dose of 40 micro mol/kg caused a significant increase in serum alanine aminotransferase activity in 17- and 30-day-old mice at 6 h post-dosing, with the extent of stimulation in 30-day-old mice being more prominent. In conclusion, tacrine was more potent in enhancing/disrupting the cognitive function, inhibiting locomotor activity as well as in causing hepatotoxicity in 17-day-old than in 30-day-old mice.

HIGH ENERGY PHYSICS: Bulgarians Sue CERN for Leniency.

PubMed

Koenig, R

2000-10-13

In cash-strapped Bulgaria, scientists are wondering whether a ticket for a front-row seat in high-energy physics is worth the price: Membership dues in CERN, the European particle physics lab, nearly equal the country's entire budget for competitive research grants. Faced with that grim statistic and a plea for leniency from Bulgaria's government, CERN's governing council is considering slashing the country's membership dues for the next 2 years.

Transgender Day of Remembrance and a Prospective Student Open House: How One Student Inspired a School to Do Both

ERIC Educational Resources Information Center

Fusarelli, Bonnie C.; Eaton, Lucy E.

2011-01-01

This case study explores the challenges a school leader faced when her commitment to diversity was tested by a scheduling conflict. The school principal approved a Transgender Day of Remembrance but then realized that it was scheduled for the same night as the school's Open House to recruit prospective students. The case study provides an…

Hands on CERN: A Well-Used Physics Education Project

ERIC Educational Resources Information Center

Johansson, K. E.

2006-01-01

The "Hands on CERN" education project makes it possible for students and teachers to get close to the forefront of scientific research. The project confronts the students with contemporary physics at its most fundamental level with the help of particle collisions from the DELPHI particle physics experiment at CERN. It now exists in 14 languages…

History of Cern

ScienceCinema

None

2017-12-09

Cérémonie à l'occasion de l'apparition du premier volume du livre sur l'histoire du Cern, avec plusieurs personnes présentes qui jouaient un rôle important dans cette organisation européenne couronnée de succès grâce à l'esprit des membres fondateurs qui est et restera essentiel

Prospects for observation at CERN in NA62

NASA Astrophysics Data System (ADS)

Hahn, F.; NA62 Collaboration; Aglieri Rinella, G.; Aliberti, R.; Ambrosino, F.; Angelucci, B.; Antonelli, A.; Anzivino, G.; Arcidiacono, R.; Azhinenko, I.; Balev, S.; Bendotti, J.; Biagioni, A.; Biino, C.; Bizzeti, A.; Blazek, T.; Blik, A.; Bloch-Devaux, B.; Bolotov, V.; Bonaiuto, V.; Bragadireanu, M.; Britton, D.; Britvich, G.; Brook, N.; Bucci, F.; Butin, F.; Capitolo, E.; Capoccia, C.; Capussela, T.; Carassiti, V.; Cartiglia, N.; Cassese, A.; Catinaccio, A.; Cecchetti, A.; Ceccucci, A.; Cenci, P.; Cerny, V.; Cerri, C.; Chikilev, O.; Ciaranfi, R.; Collazuol, G.; Cooke, P.; Cooper, P.; Corradi, G.; Cortina Gil, E.; Costantini, F.; Cotta Ramusino, A.; Coward, D.; D'Agostini, G.; Dainton, J.; Dalpiaz, P.; Danielsson, H.; Degrange, J.; De Simone, N.; Di Filippo, D.; Di Lella, L.; Dixon, N.; Doble, N.; Duk, V.; Elsha, V.; Engelfried, J.; Enik, T.; Falaleev, V.; Fantechi, R.; Federici, L.; Fiorini, M.; Fry, J.; Fucci, A.; Fulton, L.; Gallorini, S.; Gatignon, L.; Gianoli, A.; Giudici, S.; Glonti, L.; Goncalves Martins, A.; Gonnella, F.; Goudzovski, E.; Guida, R.; Gushchin, E.; Hahn, F.; Hallgren, B.; Heath, H.; Herman, F.; Hutchcroft, D.; Iacopini, E.; Jamet, O.; Jarron, P.; Kampf, K.; Kaplon, J.; Karjavin, V.; Kekelidze, V.; Kholodenko, S.; Khoriauli, G.; Khudyakov, A.; Kiryushin, Yu; Kleinknecht, K.; Kluge, A.; Koval, M.; Kozhuharov, V.; Krivda, M.; Kudenko, Y.; Kunze, J.; Lamanna, G.; Lazzeroni, C.; Leitner, R.; Lenci, R.; Lenti, M.; Leonardi, E.; Lichard, P.; Lietava, R.; Litov, L.; Lomidze, D.; Lonardo, A.; Lurkin, N.; Madigozhin, D.; Maire, G.; Makarov, A.; Mannelli, I.; Mannocchi, G.; Mapelli, A.; Marchetto, F.; Massarotti, P.; Massri, K.; Matak, P.; Mazza, G.; Menichetti, E.; Mirra, M.; Misheva, M.; Molokanova, N.; Morant, J.; Morel, M.; Moulson, M.; Movchan, S.; Munday, D.; Napolitano, M.; Newson, F.; Norton, A.; Noy, M.; Nuessle, G.; Obraztsov, V.; Padolski, S.; Page, R.; Palladino, V.; Pardons, A.; Pedreschi, E.; Pepe, M.; Perez Gomez, F.; Perrin-Terrin, M.; Petrov, P.; Petrucci, F.; Piandani, R.; Piccini, M.; Pietreanu, D.; Pinzino, J.; Pivanti, M.; Polenkevich, I.; Popov, I.; Potrebenikov, Yu; Protopopescu, D.; Raffaelli, F.; Raggi, M.; Riedler, P.; Romano, A.; Rubin, P.; Ruggiero, G.; Russo, V.; Ryjov, V.; Salamon, A.; Salina, G.; Samsonov, V.; Santovetti, E.; Saracino, G.; Sargeni, F.; Schifano, S.; Semenov, V.; Sergi, A.; Serra, M.; Shkarovskiy, S.; Sotnikov, A.; Sougonyaev, V.; Sozzi, M.; Spadaro, T.; Spinella, F.; Staley, R.; Statera, M.; Sutcliffe, P.; Szilasi, N.; Tagnani, D.; Valdata-Nappi, M.; Valente, P.; Vasile, M.; Vassilieva, V.; Velghe, B.; Veltri, M.; Venditti, S.; Vormstein, M.; Wahl, H.; Wanke, R.; Wertelaers, P.; Winhart, A.; Winston, R.; Wrona, B.; Yushchenko, O.; Zamkovsky, M.; Zinchenko, A.

2015-07-01

The rare decays are excellent processes to probe the Standard Model and indirectly search for new physics complementary to the direct LHC searches. The NA62 experiment at CERN SPS aims to collect and analyse O(1013) kaon decays before the CERN long-shutdown 2 (in 2018). This will allow to measure the branching ratio to a level of 10% accuracy. The experimental apparatus has been commissioned during a first run in autumn 2014.

Experience of public procurement of Open Compute servers

NASA Astrophysics Data System (ADS)

Bärring, Olof; Guerri, Marco; Bonfillou, Eric; Valsan, Liviu; Grigore, Alexandru; Dore, Vincent; Gentit, Alain; Clement, Benoît; Grossir, Anthony

2015-12-01

The Open Compute Project. OCP (http://www.opencompute.org/). was launched by Facebook in 2011 with the objective of building efficient computing infrastructures at the lowest possible cost. The technologies are released as open hardware. with the goal to develop servers and data centres following the model traditionally associated with open source software projects. In 2013 CERN acquired a few OCP servers in order to compare performance and power consumption with standard hardware. The conclusions were that there are sufficient savings to motivate an attempt to procure a large scale installation. One objective is to evaluate if the OCP market is sufficiently mature and broad enough to meet the constraints of a public procurement. This paper summarizes this procurement. which started in September 2014 and involved the Request for information (RFI) to qualify bidders and Request for Tender (RFT).

Critical assessment of day time traffic noise level at curbside open-air microenvironment of Kolkata City, India.

PubMed

Kundu Chowdhury, Anirban; Debsarkar, Anupam; Chakrabarty, Shibnath

2015-01-01

The objective of the research work is to assess day time traffic noise level at curbside open-air microenvironment of Kolkata city, India under heterogeneous environmental conditions. Prevailing traffic noise level in terms of A-weighted equivalent noise level (Leq) at the microenvironment was in excess of 12.6 ± 2.1 dB(A) from the day time standard of 65 dB(A) for commercial area recommended by the Central Pollution Control Board (CPCB) of India. Noise Climate and Traffic Noise Index of the microenvironment were accounted for 13 ± 1.8 dB(A) and 88.8 ± 6.1 dB(A) respectively. A correlation analysis explored that prevailing traffic noise level of the microenvironment had weak negative (-0.21; p < 0.01) and very weak positive (0.19; p < 0.01) correlation with air temperature and relative humidity. A Varimax rotated principal component analysis explored that motorized traffic volume had moderate positive loading with background noise component (L90, L95, L99) and prevailing traffic noise level had very strong positive loading with peak noise component (L1, L5, L10). Background and peak noise component cumulatively explained 80.98 % of variance in the data set. Traffic noise level at curbside open-air microenvironment of Kolkata City was higher than the standard recommended by CPCB of India. It was highly annoying also. Air temperature and relative humidity had little influence and the peak noise component had the most significant influence on the prevailing traffic noise level at curbside open-air microenvironment. Therefore, traffic noise level at the microenvironment of the city can be reduced with careful honking and driving.

CERN and 60 years of science for peace

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heuer, Rolf-Dieter, E-mail: Rolf.Heuer@cern.ch

2015-02-24

This paper presents CERN as it celebrates its 60{sup th} Anniversary since its founding. The presentation first discusses the mission of CERN and its role as an inter-governmental Organization. The paper also reviews aspects of the particle physics research programme, looking at both current and future accelerator-based facilities at the high-energy and intensity frontiers. Finally, the paper considers issues beyond fundamental research, such as capacity-building and the interface between Art and Science.

43 CFR 4.905 - What if a due date falls on a day the Department or relevant office is not open for business?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What if a due date falls on a day the... Appeals Concerning Federal Oil and Gas Royalties and Related Matters § 4.905 What if a due date falls on a day the Department or relevant office is not open for business? If a due date under this subpart falls...

43 CFR 4.905 - What if a due date falls on a day the Department or relevant office is not open for business?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false What if a due date falls on a day the... Appeals Concerning Federal Oil and Gas Royalties and Related Matters § 4.905 What if a due date falls on a day the Department or relevant office is not open for business? If a due date under this subpart falls...

43 CFR 4.905 - What if a due date falls on a day the Department or relevant office is not open for business?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false What if a due date falls on a day the... Appeals Concerning Federal Oil and Gas Royalties and Related Matters § 4.905 What if a due date falls on a day the Department or relevant office is not open for business? If a due date under this subpart falls...

43 CFR 4.905 - What if a due date falls on a day the Department or relevant office is not open for business?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false What if a due date falls on a day the... Appeals Concerning Federal Oil and Gas Royalties and Related Matters § 4.905 What if a due date falls on a day the Department or relevant office is not open for business? If a due date under this subpart falls...

43 CFR 4.905 - What if a due date falls on a day the Department or relevant office is not open for business?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true What if a due date falls on a day the... Appeals Concerning Federal Oil and Gas Royalties and Related Matters § 4.905 What if a due date falls on a day the Department or relevant office is not open for business? If a due date under this subpart falls...

CERN's approach to public outreach

NASA Astrophysics Data System (ADS)

Landua, Rolf

2016-03-01

CERN's communication goes beyond publishing scientific results. Education and outreach are equally important ways of communicating with the general public, and in particular with the young generation. Over the last decade, CERN has significantly increased its efforts to accommodate the very large interest of the general public (about 300,000 visit requests per year), by ramping up its capacity for guided tours from 25,000 to more than 100,000 visitors per year, by creating six new of state-of-the-art exhibitions on-site, by building and operating a modern physics laboratory for school teachers and students, and by showing several traveling exhibitions in about 10 countries per year. The offer for school teachers has also been expanded, to 35-40 weeks of teacher courses with more than 1000 participants from more than 50 countries per year. The talk will give an overview about these and related activities.

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

McAllister, Liam

2018-05-14

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-22

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons.Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

Sen, Ashoke

2017-12-18

Part 7.The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-06-28

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-23

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2017-12-09

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-02-09

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental InteractionS". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

McAllister, Liam

2018-05-24

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe";. The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions".This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde. Local organizers: A. Uranga, J. Walcher

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

Sen, Ashoke

2018-04-27

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network". The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher.

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2010-01-22

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series ofmore » pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher« less

CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

ScienceCinema

None

2018-05-23

The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe";. The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamental Interactions". This edition of the school is not funded by the European Union. The school is funded by the CERN Theory Division, and the Arnold Sommerfeld Center at Ludwig-Maximilians University of Munich. Scientific committee: M. Gaberdiel, D. Luest, A. Sevrin, J. Simon, K. Stelle, S. Theisen, A. Uranga, A. Van Proeyen, E. Verlinde Local organizers: A. Uranga, J. Walcher

Single nucleotide polymorphisms in specific candidate genes are associated with phenotypic differences in days open for first lactation in Holstein cows

USDA-ARS?s Scientific Manuscript database

Previously, a candidate gene approach identified 51 single nucleotide polymorphisms (SNP) associated with genetic merit for reproductive traits and 26 associated with genetic merit for production in dairy bulls. We evaluated association of the 77 SNPs with days open (DO) for first lactation in a pop...

Neutrino Factory Plans at CERN

NASA Astrophysics Data System (ADS)

Riche, J. A.

2002-10-01

The considerable interest raised by the discovery of neutrino oscillations and recent progress in studies of muon colliders has triggered interest in considering a neutrino factory at CERN. This paper explains the reference scenario, indicates the other possible choices and mentions the R&D that are foreseen.

Endovascular abdominal aortic aneurysm repair is more profitable than open repair based on contribution margin per day.

PubMed

Rosenberg, Barry L; Comstock, Matthew C; Butz, David A; Taheri, Paul A; Williams, David M; Upchurch, Gilbert R

2005-03-01

Earlier studies have reported that endovascular abdominal aortic aneurysm (EAAA) repair yields lower total profit margins than open AAA (OAAA) repair. This study compared EAAA versus OAAA based on contribution margin per day, which may better measure profitability of new clinical technologies. Contribution margin equals revenue less variable direct costs (VDCs). VDCs capture incremental resources tied directly to individual patients' activity (eg, invoice price of endograft device, nursing labor). Overhead costs factor into total margin, but not contribution margin. The University of Michigan Health System's cost accounting system was used to extract fiscal year 2002-2003 information on revenue, total margin, contribution margin, and duration of stay for Medicare patients with principal diagnosis of AAA (ICD-9 code 441.4). OAAA had revenues of $37,137 per case versus $28,960 for EAAA, similar VDCs per case, and thus higher contribution margin per case ($24,404 for OAAA vs $13,911 for EAAA, P < .001). However, OAAA had significantly longer mean duration of stay per case (10.2 days vs 2.2 days, P < .001). Therefore, mean contribution margin per day was $2948 for OAAA, but $8569 for EAAA ( P < .001). On the basis of contribution margin per day, EAAA repair dominates OAAA repair. The shorter duration of stay with EAAA allows higher throughput, fuller overhead amortization, better use of scarce inpatient beds, and higher health system profits. Surgeons must understand overhead allocation to devices, especially when new technologies cut duration of stay markedly.

CERN launches high-school internship programme

NASA Astrophysics Data System (ADS)

Johnston, Hamish

2017-07-01

The CERN particle-physics lab has hosted 22 high-school students from Hungary in a pilot programme designed to show teenagers how science, technology, engineering and mathematics is used at the particle-physics lab.

Open access, open education resources and open data in Uganda.

PubMed

Salvo, Ivana Di; Mwoka, Meggie; Kwaga, Teddy; Rukundo, Priscilla Aceng; Ernest, Dennis Ssesanga; Osaheni, Louis Aikoriogie; John, Kasibante; Shafik, Kasirye; de Sousa, Agostinho Moreira

2015-01-01

As a follow up to OpenCon 2014, International Federation of Medical Students' Associations (IFMSA) students organized a 3 day workshop Open Access, Open Education Resources and Open Data in Kampala from 15-18 December 2014. One of the aims of the workshop was to engage the Open Access movement in Uganda which encompasses the scientific community, librarians, academia, researchers and students. The IFMSA students held the workshop with the support of: Consortium for Uganda University Libraries (CUUL), The Right to Research Coalition, Electronic Information for Libraries (EIFL), Makerere University, International Health Sciences University (IHSU), Pan African Medical Journal (PAMJ) and the Centre for Health Human Rights and Development (CEHURD). All these organizations are based or have offices in Kampala. The event culminated in a meeting with the Science and Technology Committee of Parliament of Uganda in order to receive the support of the Ugandan Members of Parliament and to make a concrete change for Open Access in the country.

RainyDay: An Online, Open-Source Tool for Physically-based Rainfall and Flood Frequency Analysis

NASA Astrophysics Data System (ADS)

Wright, D.; Yu, G.; Holman, K. D.

2017-12-01

Flood frequency analysis in ungaged or changing watersheds typically requires rainfall intensity-duration-frequency (IDF) curves combined with hydrologic models. IDF curves only depict point-scale rainfall depth, while true rainstorms exhibit complex spatial and temporal structures. Floods result from these rainfall structures interacting with watershed features such as land cover, soils, and variable antecedent conditions as well as river channel processes. Thus, IDF curves are traditionally combined with a variety of "design storm" assumptions such as area reduction factors and idealized rainfall space-time distributions to translate rainfall depths into inputs that are suitable for flood hydrologic modeling. The impacts of such assumptions are relatively poorly understood. Meanwhile, modern precipitation estimates from gridded weather radar, grid-interpolated rain gages, satellites, and numerical weather models provide more realistic depictions of rainfall space-time structure. Usage of such datasets for rainfall and flood frequency analysis, however, are hindered by relatively short record lengths. We present RainyDay, an open-source stochastic storm transposition (SST) framework for generating large numbers of realistic rainfall "scenarios." SST "lengthens" the rainfall record by temporal resampling and geospatial transposition of observed storms to extract space-time information from regional gridded rainfall data. Relatively short (10-15 year) records of bias-corrected radar rainfall data are sufficient to estimate rainfall and flood events with much longer recurrence intervals including 100-year and 500-year events. We describe the SST methodology as implemented in RainyDay and compare rainfall IDF results from RainyDay to conventional estimates from NOAA Atlas 14. Then, we demonstrate some of the flood frequency analysis properties that are possible when RainyDay is integrated with a distributed hydrologic model, including robust estimation of flood

The Evolution of CERN EDMS

NASA Astrophysics Data System (ADS)

Wardzinska, Aleksandra; Petit, Stephan; Bray, Rachel; Delamare, Christophe; Garcia Arza, Griselda; Krastev, Tsvetelin; Pater, Krzysztof; Suwalska, Anna; Widegren, David

2015-12-01

Large-scale long-term projects such as the LHC require the ability to store, manage, organize and distribute large amounts of engineering information, covering a wide spectrum of fields. This information is a living material, evolving in time, following specific lifecycles. It has to reach the next generations of engineers so they understand how their predecessors designed, crafted, operated and maintained the most complex machines ever built. This is the role of CERN EDMS. The Engineering and Equipment Data Management Service has served the High Energy Physics Community for over 15 years. It is CERN's official PLM (Product Lifecycle Management), supporting engineering communities in their collaborations inside and outside the laboratory. EDMS is integrated with the CAD (Computer-aided Design) and CMMS (Computerized Maintenance Management) systems used at CERN providing tools for engineers who work in different domains and who are not PLM specialists. Over the years, human collaborations and machines grew in size and complexity. So did EDMS: it is currently home to more than 2 million files and documents, and has over 6 thousand active users. In April 2014 we released a new major version of EDMS, featuring a complete makeover of the web interface, improved responsiveness and enhanced functionality. Following the results of user surveys and building upon feedback received from key users group, we brought what we think is a system that is more attractive and makes it easy to perform complex tasks. In this paper we will describe the main functions and the architecture of EDMS. We will discuss the available integration options, which enable further evolution and automation of engineering data management. We will also present our plans for the future development of EDMS.

Bioinformatics Challenge Days

DTIC Science & Technology

2013-12-30

MIT Lincoln Laboratory in cooperation with Edgewood Chemical Biological Center (ECBC). These events explored the utility of a short-term “ hack day...conceived as an experiment applying a short “ hack day” format to bioinformatics problems of interest to DTRA. Participants of diverse technical...organizers took note of different types of previous hack day formats that had been very open-ended (i.e., gave participants a collection of hardware or

Open versus laparoscopic appendectomy.

PubMed

Herman, J; Duda, M; Lovecek, M; Svach, I

2003-01-01

To asses the role of laparoscopic appendectomy in the treatment of acute as well as chronic appendicitis on the basis of our own experiences. From the set of 849 patients treated with appendectomy (from January 1993 to December 2000) 331 were singled out, i.e.; those unable to work for some time and thus being on sickness benefit who asked for a medical certificate. They were operated on for either acute or chronic appendicitis. In our set of 331 patients (158 males, 173 females, the average age 29.4) open appendectomy was performed on 179 patients and laparoscopic appendectomy on 152. Laparoscopic appendectomy was performed in 43 males (28%) and 109 females (72%); open appendectomy in 115 males (64%) and 64 females (36%). Laparoscopic appendectomy took 53.7 +/- 18.1 minutes, open appendectomy took 43.6 +/- 8.99 minutes. The time of work disablement is longer in open appendectomy (open appendectomy: 41.2 +/- 9.91 days; laparoscopic appendectomy; 29.1 +/- 15.11 days). A significant difference (p < 0.00001) can be seen in the length of hospitalization (laparoscopic appendectomy: 5.0 +/- 2.75 days, open appendectomy: 8.3 +/- 2.83 days). Patients who undergo laparoscopic appendectomy spent less time in hospital, and they can return to work rather earlier. On the other hand the time of surgery is longer. Higher cost is compensated for with shorter hospitalization and early return to work.

Medical Applications at CERN and the ENLIGHT Network

PubMed Central

Dosanjh, Manjit; Cirilli, Manuela; Myers, Steve; Navin, Sparsh

2016-01-01

State-of-the-art techniques derived from particle accelerators, detectors, and physics computing are routinely used in clinical practice and medical research centers: from imaging technologies to dedicated accelerators for cancer therapy and nuclear medicine, simulations, and data analytics. Principles of particle physics themselves are the foundation of a cutting edge radiotherapy technique for cancer treatment: hadron therapy. This article is an overview of the involvement of CERN, the European Organization for Nuclear Research, in medical applications, with specific focus on hadron therapy. It also presents the history, achievements, and future scientific goals of the European Network for Light Ion Hadron Therapy, whose co-ordination office is at CERN. PMID:26835422

Medical Applications at CERN and the ENLIGHT Network.

PubMed

Dosanjh, Manjit; Cirilli, Manuela; Myers, Steve; Navin, Sparsh

2016-01-01

State-of-the-art techniques derived from particle accelerators, detectors, and physics computing are routinely used in clinical practice and medical research centers: from imaging technologies to dedicated accelerators for cancer therapy and nuclear medicine, simulations, and data analytics. Principles of particle physics themselves are the foundation of a cutting edge radiotherapy technique for cancer treatment: hadron therapy. This article is an overview of the involvement of CERN, the European Organization for Nuclear Research, in medical applications, with specific focus on hadron therapy. It also presents the history, achievements, and future scientific goals of the European Network for Light Ion Hadron Therapy, whose co-ordination office is at CERN.

Evaluation of the Huawei UDS cloud storage system for CERN specific data

NASA Astrophysics Data System (ADS)

Zotes Resines, M.; Heikkila, S. S.; Duellmann, D.; Adde, G.; Toebbicke, R.; Hughes, J.; Wang, L.

2014-06-01

Cloud storage is an emerging architecture aiming to provide increased scalability and access performance, compared to more traditional solutions. CERN is evaluating this promise using Huawei UDS and OpenStack SWIFT storage deployments, focusing on the needs of high-energy physics. Both deployed setups implement S3, one of the protocols that are emerging as a standard in the cloud storage market. A set of client machines is used to generate I/O load patterns to evaluate the storage system performance. The presented read and write test results indicate scalability both in metadata and data perspectives. Futher the Huawei UDS cloud storage is shown to be able to recover from a major failure of losing 16 disks. Both cloud storages are finally demonstrated to function as back-end storage systems to a filesystem, which is used to deliver high energy physics software.

Ceremony 25th birthday Cern

ScienceCinema

None

2018-05-18

Celebration of CERN's 25th birthday with a speech by L. Van Hove and J.B. Adams, musical interludes by Ms. Mey and her colleagues (starting with Beethoven). The general managers then proceed with the presentation of souvenirs to members of the personnel who have 25 years of service in the organization. A gesture of recognition is also given to Zwerner.

Optical fibres in the radiation environment of CERN

NASA Astrophysics Data System (ADS)

Guillermain, E.

2017-11-01

CERN, the European Organization for Nuclear Research (in Geneva, Switzerland), is home to a complex scientific instrument: the 27-kilometre Large Hadron Collider (LHC) collides beams of high-energy particles at close to the speed of light. Optical fibres are widely used at CERN, both in surface areas (e.g. for inter-building IT networks) and in the accelerator complex underground (e.g. for cryogenics, vacuum, safety systems). Optical fibres in the accelerator are exposed to mixed radiation fields (mainly composed of protons, pions, neutrons and other hadrons, gamma rays and electrons), with dose rates depending on the particular installation zone, and with radiation levels often significantly higher than those encountered in space. In the LHC and its injector chain radiation levels range from relatively low annual doses of a few Gy up to hundreds of kGy. Optical fibres suffer from Radiation Induced Attenuation (RIA, expressed in dB per unit length) that affect light transmission and which depends on the irradiation conditions (e.g. dose rate, total dose, temperature). In the CERN accelerator complex, the failure of an optical link can affect the proper functionality of control or monitoring systems and induce the interruption of the accelerator operation. The qualification of optical fibres for installation in critical radiation areas is therefore crucial. Thus, all optical fibre types installed in radiation areas at CERN are subject to laboratory irradiation tests, in order to evaluate their RIA at different total dose and dose rates. This allows the selection of the appropriate optical fibre type (conventional or radiation resistant) compliant with the requirements of each installation. Irradiation tests are performed in collaboration with Fraunhofer INT (irradiation facilities and expert team in Euskirchen, Germany). Conventional off-the-shelf optical fibres can be installed for optical links exposed to low radiation levels (i.e. annual dose typically below few

Single embryo transfer by Day 3 time-lapse selection versus Day 5 conventional morphological selection: a randomized, open-label, non-inferiority trial.

PubMed

Yang, Lanlin; Cai, Sufen; Zhang, Shuoping; Kong, Xiangyi; Gu, Yifan; Lu, Changfu; Dai, Jing; Gong, Fei; Lu, Guangxiu; Lin, Ge

2018-05-01

Does single cleavage-stage (Day 3) embryo transfer using a time-lapse (TL) hierarchical classification model achieve comparable ongoing pregnancy rates (OPR) to single blastocyst (Day 5) transfer by conventional morphological (CM) selection? Day 3 single embryo transfer (SET) with a hierarchical classification model had a significantly lower OPR compared with Day 5 SET with CM selection. Cleavage-stage SET is an alternative to blastocyst SET. Time-lapse imaging assists better embryo selection, based on studies of pregnancy outcomes when adding time-lapse imaging to CM selection at the cleavage or blastocyst stage. This single-centre, randomized, open-label, active-controlled, non-inferiority study included 600 women between October 2015 and April 2017. Eligible patients were Chinese females, aged ≤36 years, who were undergoing their first or second fresh IVF cycle using their own oocytes, and who had FSH levels ≤12 IU/mL on Day 3 of the cycle and 10 or more oocytes retrieved. Patients who had underlying uterine conditions, oocyte donation, recurrent pregnancy loss, abnormal oocytes or <6 normally fertilized embryos (2PN) were excluded from the study participation. Patients were randomized 1:1 to either the cleavage-stage SET with a time-lapse hierarchical classification model for selection (D3 + TL) or blastocyst SET with CM selection (D5 + CM). All normally fertilized zygotes were cultured in Primo Vision. The study was conducted at a tertiary IVF centre (CITIC-Xiangya) and OPR was the primary outcome. A total of 600 patients were randomized to the two groups, among which 585 (D3 + TL = 290, D5 + CM = 295) were included in the Modified-intention-to-treat (mITT) population and 517 (D3 + TL = 261, D5 + CM = 256) were included in the PP population. In the per protocol (PP) population, OPR was significantly lower in the D3 group (59.4%, 155/261) than in the D5 group (68.4%, 175/256) (difference: -9.0%, 95% CI: -17.1%, -0.7%, P = 0.03). Analysis in mITT population

TOWARDS A NOVEL MODULAR ARCHITECTURE FOR CERN RADIATION MONITORING.

PubMed

Boukabache, Hamza; Pangallo, Michel; Ducos, Gael; Cardines, Nicola; Bellotta, Antonio; Toner, Ciarán; Perrin, Daniel; Forkel-Wirth, Doris

2017-04-01

The European Organization for Nuclear Research (CERN) has the legal obligation to protect the public and the people working on its premises from any unjustified exposure to ionising radiation. In this context, radiation monitoring is one of the main concerns of the Radiation Protection Group. After 30 y of reliable service, the ARea CONtroller (ARCON) system is approaching the end of its lifecycle, which raises the need for new, more efficient radiation monitors with a high level of modularity to ensure better maintainability. Based on these two main principles, new detectors are currently being developed that will be capable of measuring very low dose rates down to 50 nSv h-1, whilst being able to measure radiation over an extensive range of 8 decades without any auto scaling. To reach these performances, CERN Radiation MOnitoring Electronics (CROME), the new generation of CERN radiation monitors, is based on the versatile architecture that includes new read-out electronics developed by the Instrumentation and Logistics section of the CERN Radiation Protection Group as well as a reconfigurable system on chip capable of performing complex processing calculations. Beside the capabilities of CROME to continuously measure the ambient dose rate, the system generates radiation alarms, provides interlock signals, drives alarm display units through a fieldbus and provides long-term, permanent and reliable data logging. The measurement tests performed during the first phase of the development show very promising results that pave the way to the second phase: the certification. © The Author 2016. Published by Oxford University Press.

TOWARDS A NOVEL MODULAR ARCHITECTURE FOR CERN RADIATION MONITORING

PubMed Central

Boukabache, Hamza; Pangallo, Michel; Ducos, Gael; Cardines, Nicola; Bellotta, Antonio; Toner, Ciarán; Perrin, Daniel; Forkel-Wirth, Doris

2017-01-01

Abstract The European Organization for Nuclear Research (CERN) has the legal obligation to protect the public and the people working on its premises from any unjustified exposure to ionising radiation. In this context, radiation monitoring is one of the main concerns of the Radiation Protection Group. After 30 y of reliable service, the ARea CONtroller (ARCON) system is approaching the end of its lifecycle, which raises the need for new, more efficient radiation monitors with a high level of modularity to ensure better maintainability. Based on these two main principles, new detectors are currently being developed that will be capable of measuring very low dose rates down to 50 nSv h−1, whilst being able to measure radiation over an extensive range of 8 decades without any auto scaling. To reach these performances, CERN Radiation MOnitoring Electronics (CROME), the new generation of CERN radiation monitors, is based on the versatile architecture that includes new read-out electronics developed by the Instrumentation and Logistics section of the CERN Radiation Protection Group as well as a reconfigurable system on chip capable of performing complex processing calculations. Beside the capabilities of CROME to continuously measure the ambient dose rate, the system generates radiation alarms, provides interlock signals, drives alarm display units through a fieldbus and provides long-term, permanent and reliable data logging. The measurement tests performed during the first phase of the development show very promising results that pave the way to the second phase: the certification. PMID:27909154

75 FR 56920 - Express Mail Open and Distribute and Priority Mail Open and Distribute

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-17

... POSTAL SERVICE 39 CFR Part 111 Express Mail Open and Distribute and Priority Mail Open and...] Open and Distribute containers. The Postal Service also proposes to revise the service commitment for Express Mail Open and Distribute as a guaranteed end of day product; and to add a five-pound minimum...

WorldWide Web: Hypertext from CERN.

ERIC Educational Resources Information Center

Nickerson, Gord

1992-01-01

Discussion of software tools for accessing information on the Internet focuses on the WorldWideWeb (WWW) system, which was developed at the European Particle Physics Laboratory (CERN) in Switzerland to build a worldwide network of hypertext links using available networking technology. Its potential for use with multimedia documents is also…

Towards a 21st century telephone exchange at CERN

NASA Astrophysics Data System (ADS)

Valentín, F.; Hesnaux, A.; Sierra, R.; Chapron, F.

2015-12-01

The advent of mobile telephony and Voice over IP (VoIP) has significantly impacted the traditional telephone exchange industry—to such an extent that private branch exchanges are likely to disappear completely in the near future. For large organisations, such as CERN, it is important to be able to smooth this transition by implementing new multimedia platforms that can protect past investments and the flexibility needed to securely interconnect emerging VoIP solutions and forthcoming developments such as Voice over LTE (VoLTE). We present the results of ongoing studies and tests at CERN of the latest technologies in this area.

NA61/SHINE facility at the CERN SPS: beams and detector system

NASA Astrophysics Data System (ADS)

Abgrall, N.; Andreeva, O.; Aduszkiewicz, A.; Ali, Y.; Anticic, T.; Antoniou, N.; Baatar, B.; Bay, F.; Blondel, A.; Blumer, J.; Bogomilov, M.; Bogusz, M.; Bravar, A.; Brzychczyk, J.; Bunyatov, S. A.; Christakoglou, P.; Cirkovic, M.; Czopowicz, T.; Davis, N.; Debieux, S.; Dembinski, H.; Diakonos, F.; Di Luise, S.; Dominik, W.; Drozhzhova, T.; Dumarchez, J.; Dynowski, K.; Engel, R.; Efthymiopoulos, I.; Ereditato, A.; Fabich, A.; Feofilov, G. A.; Fodor, Z.; Fulop, A.; Gaździcki, M.; Golubeva, M.; Grebieszkow, K.; Grzeszczuk, A.; Guber, F.; Haesler, A.; Hasegawa, T.; Hierholzer, M.; Idczak, R.; Igolkin, S.; Ivashkin, A.; Jokovic, D.; Kadija, K.; Kapoyannis, A.; Kaptur, E.; Kielczewska, D.; Kirejczyk, M.; Kisiel, J.; Kiss, T.; Kleinfelder, S.; Kobayashi, T.; Kolesnikov, V. I.; Kolev, D.; Kondratiev, V. P.; Korzenev, A.; Koversarski, P.; Kowalski, S.; Krasnoperov, A.; Kurepin, A.; Larsen, D.; Laszlo, A.; Lyubushkin, V. V.; Maćkowiak-Pawłowska, M.; Majka, Z.; Maksiak, B.; Malakhov, A. I.; Maletic, D.; Manglunki, D.; Manic, D.; Marchionni, A.; Marcinek, A.; Marin, V.; Marton, K.; Mathes, H.-J.; Matulewicz, T.; Matveev, V.; Melkumov, G. L.; Messina, M.; Mrówczyński, St.; Murphy, S.; Nakadaira, T.; Nirkko, M.; Nishikawa, K.; Palczewski, T.; Palla, G.; Panagiotou, A. D.; Paul, T.; Peryt, W.; Petukhov, O.; Pistillo, C.; Płaneta, R.; Pluta, J.; Popov, B. A.; Posiadala, M.; Puławski, S.; Puzovic, J.; Rauch, W.; Ravonel, M.; Redij, A.; Renfordt, R.; Richter-Was, E.; Robert, A.; Röhrich, D.; Rondio, E.; Rossi, B.; Roth, M.; Rubbia, A.; Rustamov, A.; Rybczyński, M.; Sadovsky, A.; Sakashita, K.; Savic, M.; Schmidt, K.; Sekiguchi, T.; Seyboth, P.; Sgalaberna, D.; Shibata, M.; Sipos, R.; Skrzypczak, E.; Słodkowski, M.; Sosin, Z.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Stroebele, H.; Susa, T.; Szuba, M.; Tada, M.; Tereshchenko, V.; Tolyhi, T.; Tsenov, R.; Turko, L.; Ulrich, R.; Unger, M.; Vassiliou, M.; Veberic, D.; Vechernin, V. V.; Vesztergombi, G.; Vinogradov, L.; Wilczek, A.; Włodarczyk, Z.; Wojtaszek-Szwarz, A.; Wyszyński, O.; Zambelli, L.; Zipper, W.

2014-06-01

NA61/SHINE (SPS Heavy Ion and Neutrino Experiment) is a multi-purpose experimental facility to study hadron production in hadron-proton, hadron-nucleus and nucleus-nucleus collisions at the CERN Super Proton Synchrotron. It recorded the first physics data with hadron beams in 2009 and with ion beams (secondary 7Be beams) in 2011. NA61/SHINE has greatly profited from the long development of the CERN proton and ion sources and the accelerator chain as well as the H2 beamline of the CERN North Area. The latter has recently been modified to also serve as a fragment separator as needed to produce the Be beams for NA61/SHINE. Numerous components of the NA61/SHINE set-up were inherited from its predecessors, in particular, the last one, the NA49 experiment. Important new detectors and upgrades of the legacy equipment were introduced by the NA61/SHINE Collaboration. This paper describes the state of the NA61/SHINE facility — the beams and the detector system — before the CERN Long Shutdown I, which started in March 2013.

Security in the CernVM File System and the Frontier Distributed Database Caching System

NASA Astrophysics Data System (ADS)

Dykstra, D.; Blomer, J.

2014-06-01

Both the CernVM File System (CVMFS) and the Frontier Distributed Database Caching System (Frontier) distribute centrally updated data worldwide for LHC experiments using http proxy caches. Neither system provides privacy or access control on reading the data, but both control access to updates of the data and can guarantee the authenticity and integrity of the data transferred to clients over the internet. CVMFS has since its early days required digital signatures and secure hashes on all distributed data, and recently Frontier has added X.509-based authenticity and integrity checking. In this paper we detail and compare the security models of CVMFS and Frontier.

"They who dream by day": parallels between Openness to Experience and dreaming.

PubMed

DeYoung, Colin G; Grazioplene, Rachael G

2013-12-01

Individuals high in the personality trait Openness to Experience appear to engage spontaneously (during wake) in processes of elaborative encoding similar to those Llewellyn identifies in both dreaming and the ancient art of memory (AAOM). Links between Openness and dreaming support the hypothesis that dreaming is part of a larger process of cognitive exploration that facilitates adaptation to new experiences.

Comparison between open and laparoscopic repair of perforated peptic ulcer disease.

PubMed

Bhogal, Ricky H; Athwal, Ruvinder; Durkin, Damien; Deakin, Mark; Cheruvu, Chandra N V

2008-11-01

The place of laparoscopic repair of perforated peptic ulcer followed by peritoneal toilet has been established, although it is not routinely practiced. This prospective study compared laparoscopic and open repair of perforated peptic ulcer disease. We evaluated whether the early results from laparoscopic repair resulted in improved patient outcome compared with conventional open repair. All patients who underwent repair of perforated peptic ulcer disease during a 12-month period in our unit were included in the study. The primary end points that were evaluated were total operative time, nasogastric tube utilisation, intravenous fluid requirement, total time of urinary catheter and abdominal drainage usage, time taken to return to normal diet, intravenous/intramuscular opiate use, time to full mobilization, and total in-patient hospital stay. Thirty-three patients underwent surgical repair of perforated peptic ulcer disease (19 laparoscopic repairs and 14 open repairs; mean age, 54.2 (range, 32-82) years). There was no increase in total operative time in patients who had undergone laparoscopic repair (mean: 61 minutes laparoscopic versus 57 minutes open). There was significantly less requirement for intravenous/intramuscular opiate analgesia in patients who had undergone laparoscopic repair (mean time to oral analgesia: 1.2 days laparoscopic versus 3.8 days open). In addition there was a significant decrease in the time that the nasogastric tube (mean: 2.1 days laparoscopic versus 3.1 days open), urinary catheter (mean: 2.3 days laparoscopic versus 3.7 days open) and abdominal drain (mean: 2.2 days laparoscopic versus 3.8 days open) were required during the postoperative period. Patients who had undergone laparoscopic repair required less intravenous fluids (mean: 1.4 days laparoscopic versus 3.1 days open) and returned to normal diet (mean: 2.3 days laparoscopic versus 4.8 days open) and full mobilization significantly earlier than those who had undergone open

Commissioning of a CERN Production and Analysis Facility Based on xrootd

NASA Astrophysics Data System (ADS)

Campana, Simone; van der Ster, Daniel C.; Di Girolamo, Alessandro; Peters, Andreas J.; Duellmann, Dirk; Coelho Dos Santos, Miguel; Iven, Jan; Bell, Tim

2011-12-01

The CERN facility hosts the Tier-0 of the four LHC experiments, but as part of WLCG it also offers a platform for production activities and user analysis. The CERN CASTOR storage technology has been extensively tested and utilized for LHC data recording and exporting to external sites according to experiments computing model. On the other hand, to accommodate Grid data processing activities and, more importantly, chaotic user analysis, it was realized that additional functionality was needed including a different throttling mechanism for file access. This paper will describe the xroot-based CERN production and analysis facility for the ATLAS experiment and in particular the experiment use case and data access scenario, the xrootd redirector setup on top of the CASTOR storage system, the commissioning of the system and real life experience for data processing and data analysis.

CernVM WebAPI - Controlling Virtual Machines from the Web

NASA Astrophysics Data System (ADS)

Charalampidis, I.; Berzano, D.; Blomer, J.; Buncic, P.; Ganis, G.; Meusel, R.; Segal, B.

2015-12-01

Lately, there is a trend in scientific projects to look for computing resources in the volunteering community. In addition, to reduce the development effort required to port the scientific software stack to all the known platforms, the use of Virtual Machines (VMs)u is becoming increasingly popular. Unfortunately their use further complicates the software installation and operation, restricting the volunteer audience to sufficiently expert people. CernVM WebAPI is a software solution addressing this specific case in a way that opens wide new application opportunities. It offers a very simple API for setting-up, controlling and interfacing with a VM instance in the users computer, while in the same time offloading the user from all the burden of downloading, installing and configuring the hypervisor. WebAPI comes with a lightweight javascript library that guides the user through the application installation process. Malicious usage is prohibited by offering a per-domain PKI validation mechanism. In this contribution we will overview this new technology, discuss its security features and examine some test cases where it is already in use.

Open Media Training Session

ScienceCinema

None

2017-12-09

Have you ever wondered how the media work and why some topics make it into the news and other don't? Would you like to know how to (and how not to) give an interview to a journalist? With the LHC preparing for first collisions at high energies, the world's media are again turning their attention to CERN. We're all likely to be called upon to explain what is happening at CERN to media, friends and neighbours. The seminar will be given by BBC television news journalists Liz Pike and Nadia Marchant, and will deal with the kind of questions we're likely to be confronted with through the restart period. Follow the webcast: http://webcast.cern.ch/

Publisher's Note: EPL and Open Access Articles

NASA Astrophysics Data System (ADS)

Ancarani, Barbara; Brassac, Catherine; Burr, Frédéric; Dose, Volker; King, Caroline

2008-01-01

In May 2007 the EPLA Board of Directors welcomed the CERN initiative for the creation of a Sponsoring Consortium for Open Access Publishing in Particle Physics (SCOAP3) and agreed to enter into negotiations to enable high energy physics papers to be published in EPL with selective open access. At a subsequent meeting in August 2007, the Board decided to offer substantial initial discount while open access remained a small fraction of the content of EPL. A necessary precursor to negotiation with SCOAP3 is a general open access policy. The Directors agreed that this policy should offer a free-to-read option for all authors in all sections of EPL and so provide fair opportunities across the broad range of physics covered by EPL. The policy for the journal should allow individual authors, their institutions, funding agencies or sponsoring consortia to pay for published articles to be freely available to all, permanently. The Board stressed the importance of maintaining EPL as a refereed journal with robust and reliable content, in contrast to a repository or preprint server. EPL would remain a subscription journal for content that is not free to read and authors, institutions or funding agencies may choose to pay for their articles to be open access. As an initial step in this open access venture, a single-article fee of € 1000 ( 1330) can now be paid by individuals who choose to have their article published free to all. This pricing, which is substantially discounted, ensures that EPL remains competitive with other similar journals. EPL will continue to ensure this policy is sustainable although the journal must remain financially viable and the pricing scheme will be under continual review. At this stage we welcome enquires concerning an institutional membership fee that would allow that institute to pay in advance for open access publications in EPL for authors from that institute. The fee would follow a band structure, based on the number of articles that

CERN - Six Decades of Science, Innovation, Cooperation, and Inspiration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Quigg, Chris

The European Laboratory for Particle Physics, which straddles the Swiss-French border northwest of Geneva, celebrates its sixtieth birthday in 2014 CERN is the preeminent particle-physics institution in the world, currently emphasizing the study of collisions of protons and heavy nuclei at very high energies and the exploration of physics on the electroweak scale (energies where electromagnetism and the weak nuclear force merge). With brilliant accomplishments in research, innovation, and education, and a sustained history of cooperation among people from different countries and cultures, CERN ranks as one of the signal achievements of the postwar European Project. For physicists the worldmore » over, the laboratory is a source of pride and inspiration.« less

HIGH ENERGY PHYSICS: CERN Link Breathes Life Into Russian Physics.

PubMed

Stone, R

2000-10-13

Without fanfare, 600 Russian scientists here at CERN, the European particle physics laboratory, are playing key roles in building the Large Hadron Collider (LHC), a machine that will explore fundamental questions such as why particles have mass, as well as search for exotic new particles whose existence would confirm supersymmetry, a popular theory that aims to unify the four forces of nature. In fact, even though Russia is not one of CERN's 20 member states, most top high-energy physicists in Russia are working on the LHC. Some say their work could prove the salvation of high-energy physics back home.

The 2016 Bioinformatics Open Source Conference (BOSC).

PubMed

Harris, Nomi L; Cock, Peter J A; Chapman, Brad; Fields, Christopher J; Hokamp, Karsten; Lapp, Hilmar; Muñoz-Torres, Monica; Wiencko, Heather

2016-01-01

Message from the ISCB: The Bioinformatics Open Source Conference (BOSC) is a yearly meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. BOSC has been run since 2000 as a two-day Special Interest Group (SIG) before the annual ISMB conference. The 17th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2016) took place in Orlando, Florida in July 2016. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community. The conference brought together nearly 100 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, and open and reproducible science.

Upgrade of the cryogenic CERN RF test facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pirotte, O.; Benda, V.; Brunner, O.

2014-01-29

With the large number of superconducting radiofrequency (RF) cryomodules to be tested for the former LEP and the present LHC accelerator a RF test facility was erected early in the 1990’s in the largest cryogenic test facility at CERN located at Point 18. This facility consisted of four vertical test stands for single cavities and originally one and then two horizontal test benches for RF cryomodules operating at 4.5 K in saturated helium. CERN is presently working on the upgrade of its accelerator infrastructure, which requires new superconducting cavities operating below 2 K in saturated superfluid helium. Consequently, the RFmore » test facility has been renewed in order to allow efficient cavity and cryomodule tests in superfluid helium and to improve its thermal performances. The new RF test facility is described and its performances are presented.« less

PARTICLE PHYSICS: CERN Gives Higgs Hunters Extra Month to Collect Data.

PubMed

Morton, O

2000-09-22

After 11 years of banging electrons and positrons together at higher energies than any other machine in the world, CERN, the European laboratory for particle physics, had decided to shut down the Large Electron-Positron collider (LEP) and install a new machine, the Large Hadron Collider (LHC), in its 27-kilometer tunnel. In 2005, the LHC will start bashing protons together at even higher energies. But tantalizing hints of a long-sought fundamental particle have forced CERN managers to grant LEP a month's reprieve.

Hangout with CERN: Reaching the Public with the Collaborative Tools of Social Media

NASA Astrophysics Data System (ADS)

Goldfarb, S.; Kahle, K. L. M.; Rao, A.

2014-06-01

On 4 July 2012, particle physics became a celebrity. Around 1,000,000,000 people (yes, 1 billion) [1] saw rebroadcasts of two technical presentations announcing the discovery of a new boson. The occasion was a joint seminar of the CMS [2] and ATLAS [3] collaborations, and the target audience were particle physicists. Yet the world ate it up like a sporting event. Roughly two days later, in a parallel session of ICHEP in Melbourne, Australia [4], a group of physicists decided to explain the significance of this discovery to the public. They used a tool called "Hangout", part of the relatively new Google+ social media platform [5], to converse directly with the public via a webcast videoconference. The demand to join this Hangout [6] overloaded the server several times. In the end, a compromise involving Q&A via comments was set up, and the conversation was underway. We present a new project born shortly after this experience called Hangout with CERN [7], and discuss its success in creating an effective conversational channel between the public and particle physicists. We review earlier efforts by both CMS and ATLAS contributing to this development, and then describe the current programme, involving nearly all aspects of CERN, and some topics that go well beyond that. We conclude by discussing the potential of the programme both to improve our accountability to the public and to train our community for public communication.

The 2016 Bioinformatics Open Source Conference (BOSC)

PubMed Central

Harris, Nomi L.; Cock, Peter J.A.; Chapman, Brad; Fields, Christopher J.; Hokamp, Karsten; Lapp, Hilmar; Muñoz-Torres, Monica; Wiencko, Heather

2016-01-01

Message from the ISCB: The Bioinformatics Open Source Conference (BOSC) is a yearly meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. BOSC has been run since 2000 as a two-day Special Interest Group (SIG) before the annual ISMB conference. The 17th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2016) took place in Orlando, Florida in July 2016. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community. The conference brought together nearly 100 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, and open and reproducible science. PMID:27781083

A perspective on the use of an enhanced recovery program in open, non-instrumented day surgery for degenerative lumbar and cervical spinal conditions.

PubMed

Venkata, Hari K; van Dellen, James R

2018-06-01

A means of significantly shortening patients' length of hospital stay, improving their outcome and thereby also reducing costs is to use an enhanced recovery program (ERP) which is increasingly being used in a number of surgical sub-specialties. This paper provides a perspective on its prospective use in a wide-ranging, unselected cohort of patients undergoing open spinal surgery for degenerative lumbar and cervical spinal conditions. Selected spinal cases undergoing day surgery have been increasingly reported. A prospective, unselected, consecutive cohort of 246 cases, over an 18-month period, undergoing open, non-instrumented decompression spinal surgery and using ERP (and the concept of "bundles of care") was analyzed. Nine cases could not be included as they did not fully meet the entry criteria. No routine follow-up was arranged for the study group. The ages ranged widely, from 23-90 years (mean 57). In 187 the surgery for degenerative conditions was lumbar and in 50 cervical. The ASA (American Association of Anesthesiologists) ratings were 108=1; 107=2 and 22=3. Using the United Kingdom (UK) National Health Service (NHS) definitions of length of stay 225 (95%) could be finally classified as "ambulatory" and 12 (5%) were "short stay". A sub-cohort of 126 (53.2%) were "day cases". The follow-up was >1 year for all. There were no wound infections reported; 5 postdischarge cases (2.1%) needed to be seen in the Accident and Emergency (A&E) Department (less than 4 days postsurgery), but none needed re-admission; and there were 7 re-admissions (2.5%), between 4 and 30 days, and of these 6 required a further surgical procedure. There were no long-term instability complications reported in this cohort. ERP can be used for spinal surgery. There were identifiable and correctable medical and social factors found on analysis which could significantly increase the "day cases" number to over 90%.

CERN@school: demonstrating physics with the Timepix detector

NASA Astrophysics Data System (ADS)

Whyntie, T.; Bithray, H.; Cook, J.; Coupe, A.; Eddy, D.; Fickling, R. L.; McKenna, J.; Parker, B.; Paul, A.; Shearer, N.

2015-10-01

This article shows how the Timepix hybrid silicon pixel detector, developed by the Medipix2 Collaboration, can be used by students and teachers alike to demonstrate some key aspects of any well-rounded physics curriculum with CERN@school. After an overview of the programme, the detector's capabilities for measuring and visualising ionising radiation are examined. The classification of clusters - groups of adjacent pixels - is discussed with respect to identifying the different types of particles. Three demonstration experiments - background radiation measurements, radiation profiles and the attenuation of radiation - are described; these can used as part of lessons or as inspiration for independent research projects. Results for exemplar data-sets are presented for reference, as well as details of ongoing research projects inspired by these experiments. Interested readers are encouraged to join the CERN@school Collaboration and so contribute to achieving the programme's aim of inspiring the next generation of scientists and engineers.

Ceremony 25th birthday Cern

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2006-05-08

Célébration du 25ème anniversaire du Cern (jour par jour) avec discours de L.Van Hove et J.B.Adams, des interludes musicals offerts par Mme Mey et ses collègues (au debut 1.mouvement du quatuor avec piano no 3 de L.van Beethoven) Les directeurs généraux procéderont à la remise du souvenir aux membres de personnel ayant 25 années de service dans l'organisation. Un témoignage de reconnaissance est auss fait à l'interprète Mme Zwerner

42 CFR 417.426 - Open enrollment requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 3 2013-10-01 2013-10-01 false Open enrollment requirements. 417.426 Section 417... Open enrollment requirements. (a) Basic requirements. (1) HMOs or CMPs must provide open enrollment for Medicare beneficiaries for at least 30 consecutive days during each contract year. (2) During open...

42 CFR 417.426 - Open enrollment requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 3 2014-10-01 2014-10-01 false Open enrollment requirements. 417.426 Section 417... Open enrollment requirements. (a) Basic requirements. (1) HMOs or CMPs must provide open enrollment for Medicare beneficiaries for at least 30 consecutive days during each contract year. (2) During open...

42 CFR 417.426 - Open enrollment requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 3 2012-10-01 2012-10-01 false Open enrollment requirements. 417.426 Section 417... Open enrollment requirements. (a) Basic requirements. (1) HMOs or CMPs must provide open enrollment for Medicare beneficiaries for at least 30 consecutive days during each contract year. (2) During open...

75 FR 23587 - Annual Seattle Yacht Club's “Opening Day” Marine Parade

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-04

... Seattle Yacht Club's ``Opening Day'' Marine Parade AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement..., Portage Cut (Montlake Cut), and Union Bay, WA during the Annual Seattle Yacht Club's ``Opening Day... Special Local Regulation for the annual Seattle Yacht Club's ``Opening Day'' Marine Parade in 33 CFR 100...

CERN, ESA and ESO Launch "Physics On Stage"

NASA Astrophysics Data System (ADS)

2000-03-01

countries of at least one of the participating organisations or the European Union: Austria, Belgium, Bulgaria, the Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Luxembourg, the Netherlands, Norway, Poland, Portugal, the Slovak Republic, Spain, Sweden, Switzerland, United Kingdom. Statements by the Directors General of CERN, ESA and ESO Luciano Maiani (CERN) : "Science is a critical resource for mankind and, among natural sciences, physics will continue to play a crucial role, well into the next century. The young people of Europe deserve the best possible physics teaching. An enormous resource of first class teachers, teaching materials and innovative thinking exists in our countries. The "Physics on Stage" project will bring these together to generate a new interest in physics education which will be to the long term benefit of children all over Europe. CERN is delighted to take part in this collaboration between the European Community and the continent's three leading physics research organizations." Antonio Rodotà (ESA) : "Space has become an integral part of every day life. The immense technological development that has led to this achievement has taken place and might be taken for granted. But now is the time to follow up and form the future on this basis, a future that has to made by the youth and has to give its benefits to the youth. The European Space Agency is dedicated to support the youth in its development to become a space generation. Many activities have been done and are taking place, and many more are planned for the future. Teachers and educational institutions and organisations form a key role in this development. ESA is enthusiastic about co-operating with ESO and CERN to create an opportunity to receiving ideas from the educational society and will perform a dedicated effort in finding ways to support the realisation of those ideas." Catherine Cesarsky (ESO) : "Astronomy and Astrophysics are at the very heart of

Development of the cryogenic system of AEgIS at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Derking, J. H.; Bremer, J.; Burghart, G.

2014-01-29

The AEgIS (Antimatter Experiment: Gravity, Interferometry, Spectroscopy) experiment is located at the antiproton decelerator complex of CERN. The main goal of the experiment is to perform the first direct measurement of the Earth’s gravitational acceleration on antihydrogen atoms within 1% precision. The antihydrogen is produced in a cylindrical Penning trap by combining antiprotons with positrons. To reach the precision of 1%, the antihydrogen has to be cooled to 100 mK to reduce its random velocity. A dilution refrigerator is selected to deliver the necessary cooling capacity of 100 μW at 50 mK. The AEgIS cryogenic system basically consists of cryostatsmore » for a 1-T and for a 5-T superconducting magnet, a central region cryostat, a dilution refrigerator cryostat and a measurement cryostat with a Moiré deflectometer to measure the gravitational acceleration. In autumn 2012, the 1-T cryostat, 5-T cryostat and central region cryostat were assembled and commissioned. The apparatus is cooled down in eight days using 2500 L of liquid helium and liquid nitrogen. During operation, the average consumption of liquid helium is 150 L⋅day{sup −1} and of liquid nitrogen 5 L⋅day{sup −1}. The temperature sensors at the Penning traps measured 12 K to 18 K, which is higher than expected. Simulations show that this is caused by a bad thermalization of the trap wiring. The implementation of the sub-kelvin region is foreseen for mid-2015. The antihydrogen will be cooled down to 100 mK in an ultra-cold trap consisting of multiple high-voltage electrodes made of sapphire with gold plated electrode sectors.« less

Development of the cryogenic system of AEgIS at CERN

NASA Astrophysics Data System (ADS)

Derking, J. H.; Bremer, J.; Burghart, G.; Doser, M.; Dudarev, A.; Haider, S.

2014-01-01

The AEgIS (Antimatter Experiment: Gravity, Interferometry, Spectroscopy) experiment is located at the antiproton decelerator complex of CERN. The main goal of the experiment is to perform the first direct measurement of the Earth's gravitational acceleration on antihydrogen atoms within 1% precision. The antihydrogen is produced in a cylindrical Penning trap by combining antiprotons with positrons. To reach the precision of 1%, the antihydrogen has to be cooled to 100 mK to reduce its random velocity. A dilution refrigerator is selected to deliver the necessary cooling capacity of 100 μW at 50 mK. The AEgIS cryogenic system basically consists of cryostats for a 1-T and for a 5-T superconducting magnet, a central region cryostat, a dilution refrigerator cryostat and a measurement cryostat with a Moiré deflectometer to measure the gravitational acceleration. In autumn 2012, the 1-T cryostat, 5-T cryostat and central region cryostat were assembled and commissioned. The apparatus is cooled down in eight days using 2500 L of liquid helium and liquid nitrogen. During operation, the average consumption of liquid helium is 150 Lṡday-1 and of liquid nitrogen 5 Lṡday-1. The temperature sensors at the Penning traps measured 12 K to 18 K, which is higher than expected. Simulations show that this is caused by a bad thermalization of the trap wiring. The implementation of the sub-kelvin region is foreseen for mid-2015. The antihydrogen will be cooled down to 100 mK in an ultra-cold trap consisting of multiple high-voltage electrodes made of sapphire with gold plated electrode sectors.

Short-term Outcomes After Open and Laparoscopic Colostomy Creation.

PubMed

Ivatury, Srinivas Joga; Bostock Rosenzweig, Ian C; Holubar, Stefan D

2016-06-01

Colostomy creation is a common procedure performed in colon and rectal surgery. Outcomes by technique have not been well studied. This study evaluated outcomes related to open versus laparoscopic colostomy creation. This was a retrospective review of patients undergoing colostomy creation using univariate and multivariate propensity score analyses. Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program database were included. Data on patients were obtained from the American College of Surgeons National Surgical Quality Improvement Program 2005-2011 Participant Use Data Files. We measured 30-day mortality, 30-day complications, and predictors of 30-day mortality. A total of 2179 subjects were in the open group and 1132 in the laparoscopic group. The open group had increased age (open, 64 years vs laparoscopic, 60 years), admission from facility (17.0% vs 14.9%), and disseminated cancer (26.1% vs 21.4%). All were statistically significant. The open group had a significantly higher percentage of emergency operations (24.9% vs 7.9%). Operative time was statistically different (81 vs 86 minutes). Thirty-day mortality was significantly higher in the open group (8.7% vs 3.5%), as was any 30-day complication (25.4% vs 17.0%). Propensity-matching analysis on elective patients only revealed that postoperative length of stay and rate of any wound complication were statistically higher in the open group. Multivariate analysis for mortality was performed on the full, elective, and propensity-matched cohorts; age >65 years and dependent functional status were associated with an increased risk of mortality in all of the models. This study has the potential for selection bias and limited generalizability. Colostomy creation at American College of Surgeons National Surgical Quality Improvement Program hospitals is more commonly performed open rather than laparoscopically. Patient age >65 years and dependent functional status are

The ATLAS Experiment at the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

ATLAS Collaboration; Aad, G.; Abat, E.; Abdallah, J.; Abdelalim, A. A.; Abdesselam, A.; Abdinov, O.; Abi, B. A.; Abolins, M.; Abramowicz, H.; Acerbi, E.; Acharya, B. S.; Achenbach, R.; Ackers, M.; Adams, D. L.; Adamyan, F.; Addy, T. N.; Aderholz, M.; Adorisio, C.; Adragna, P.; Aharrouche, M.; Ahlen, S. P.; Ahles, F.; Ahmad, A.; Ahmed, H.; Aielli, G.; Åkesson, P. F.; Åkesson, T. P. A.; Akimov, A. V.; Alam, S. M.; Albert, J.; Albrand, S.; Aleksa, M.; Aleksandrov, I. N.; Aleppo, M.; Alessandria, F.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alimonti, G.; Aliyev, M.; Allport, P. P.; Allwood-Spiers, S. E.; Aloisio, A.; Alonso, J.; Alves, R.; Alviggi, M. G.; Amako, K.; Amaral, P.; Amaral, S. P.; Ambrosini, G.; Ambrosio, G.; Amelung, C.; Ammosov, V. V.; Amorim, A.; Amram, N.; Anastopoulos, C.; Anderson, B.; Anderson, K. J.; Anderssen, E. C.; Andreazza, A.; Andrei, V.; Andricek, L.; Andrieux, M.-L.; Anduaga, X. S.; Anghinolfi, F.; Antonaki, A.; Antonelli, M.; Antonelli, S.; Apsimon, R.; Arabidze, G.; Aracena, I.; Arai, Y.; Arce, A. T. H.; Archambault, J. P.; Arguin, J.-F.; Arik, E.; Arik, M.; Arms, K. E.; Armstrong, S. R.; Arnaud, M.; Arnault, C.; Artamonov, A.; Asai, S.; Ask, S.; Åsman, B.; Asner, D.; Asquith, L.; Assamagan, K.; Astbury, A.; Athar, B.; Atkinson, T.; Aubert, B.; Auerbach, B.; Auge, E.; Augsten, K.; Aulchenko, V. M.; Austin, N.; Avolio, G.; Avramidou, R.; Axen, A.; Ay, C.; Azuelos, G.; Baccaglioni, G.; Bacci, C.; Bachacou, H.; Bachas, K.; Bachy, G.; Badescu, E.; Bagnaia, P.; Bailey, D. C.; Baines, J. T.; Baker, O. K.; Ballester, F.; Baltasar Dos Santos Pedrosa, F.; Banas, E.; Banfi, D.; Bangert, A.; Bansal, V.; Baranov, S. P.; Baranov, S.; Barashkou, A.; Barberio, E. L.; Barberis, D.; Barbier, G.; Barclay, P.; Bardin, D. Y.; Bargassa, P.; Barillari, T.; Barisonzi, M.; Barnett, B. M.; Barnett, R. M.; Baron, S.; Baroncelli, A.; Barone, M.; Barr, A. J.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Barrillon, P.; Barriuso Poy, A.; Barros, N.; Bartheld, V.; Bartko, H.; Bartoldus, R.; Basiladze, S.; Bastos, J.; Batchelor, L. E.; Bates, R. L.; Batley, J. R.; Batraneanu, S.; Battistin, M.; Battistoni, G.; Batusov, V.; Bauer, F.; Bauss, B.; Baynham, D. E.; Bazalova, M.; Bazan, A.; Beauchemin, P. H.; Beaugiraud, B.; Beccherle, R. B.; Beck, G. A.; Beck, H. P.; Becks, K. H.; Bedajanek, I.; Beddall, A. J.; Beddall, A.; Bednár, P.; Bednyakov, V. A.; Bee, C.; Behar Harpaz, S.; Belanger, G. A. N.; Belanger-Champagne, C.; Belhorma, B.; Bell, P. J.; Bell, W. H.; Bella, G.; Bellachia, F.; Bellagamba, L.; Bellina, F.; Bellomo, G.; Bellomo, M.; Beltramello, O.; Belymam, A.; Ben Ami, S.; Ben Moshe, M.; Benary, O.; Benchekroun, D.; Benchouk, C.; Bendel, M.; Benedict, B. H.; Benekos, N.; Benes, J.; Benhammou, Y.; Benincasa, G. P.; Benjamin, D. P.; Bensinger, J. R.; Benslama, K.; Bentvelsen, S.; Beretta, M.; Berge, D.; Bergeaas, E.; Berger, N.; Berghaus, F.; Berglund, S.; Bergsma, F.; Beringer, J.; Bernabéu, J.; Bernardet, K.; Berriaud, C.; Berry, T.; Bertelsen, H.; Bertin, A.; Bertinelli, F.; Bertolucci, S.; Besson, N.; Beteille, A.; Bethke, S.; Bialas, W.; Bianchi, R. M.; Bianco, M.; Biebel, O.; Bieri, M.; Biglietti, M.; Bilokon, H.; Binder, M.; Binet, S.; Bingefors, N.; Bingul, A.; Bini, C.; Biscarat, C.; Bischof, R.; Bischofberger, M.; Bitadze, A.; Bizzell, J. P.; Black, K. M.; Blair, R. E.; Blaising, J. J.; Blanch, O.; Blanchot, G.; Blocker, C.; Blocki, J.; Blondel, A.; Blum, W.; Blumenschein, U.; Boaretto, C.; Bobbink, G. J.; Bocci, A.; Bocian, D.; Bock, R.; Boehm, M.; Boek, J.; Bogaerts, J. A.; Bogouch, A.; Bohm, C.; Bohm, J.; Boisvert, V.; Bold, T.; Boldea, V.; Bondarenko, V. G.; Bonino, R.; Bonis, J.; Bonivento, W.; Bonneau, P.; Boonekamp, M.; Boorman, G.; Boosten, M.; Booth, C. N.; Booth, P. S. L.; Booth, P.; Booth, J. R. A.; Borer, K.; Borisov, A.; Borjanovic, I.; Bos, K.; Boscherini, D.; Bosi, F.; Bosman, M.; Bosteels, M.; Botchev, B.; Boterenbrood, H.; Botterill, D.; Boudreau, J.; Bouhova-Thacker, E. V.; Boulahouache, C.; Bourdarios, C.; Boutemeur, M.; Bouzakis, K.; Boyd, G. R.; Boyd, J.; Boyer, B. H.; Boyko, I. R.; Bozhko, N. I.; Braccini, S.; Braem, A.; Branchini, P.; Brandenburg, G. W.; Brandt, A.; Brandt, O.; Bratzler, U.; Braun, H. M.; Bravo, S.; Brawn, I. P.; Brelier, B.; Bremer, J.; Brenner, R.; Bressler, S.; Breton, D.; Brett, N. D.; Breugnon, P.; Bright-Thomas, P. G.; Brochu, F. M.; Brock, I.; Brock, R.; Brodbeck, T. J.; Brodet, E.; Broggi, F.; Broklova, Z.; Bromberg, C.; Brooijmans, G.; Brouwer, G.; Broz, J.; Brubaker, E.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruni, A.; Bruni, G.; Bruschi, M.; Buanes, T.; Buchanan, N. J.; Buchholz, P.; Budagov, I. A.; Büscher, V.; Bugge, L.; Buira-Clark, D.; Buis, E. J.; Bujor, F.; Buran, T.; Burckhart, H.; Burckhart-Chromek, D.; Burdin, S.; Burns, R.; Busato, E.; Buskop, J. J. F.; Buszello, K. P.; Butin, F.; Butler, J. M.; Buttar, C. M.; Butterworth, J.; Butterworth, J. M.; Byatt, T.; Cabrera Urbán, S.; Cabruja Casas, E.; Caccia, M.; Caforio, D.; Cakir, O.; Calafiura, P.; Calderini, G.; Calderón Terol, D.; Callahan, J.; Caloba, L. P.; Caloi, R.; Calvet, D.; Camard, A.; Camarena, F.; Camarri, P.; Cambiaghi, M.; Cameron, D.; Cammin, J.; Campabadal Segura, F.; Campana, S.; Canale, V.; Cantero, J.; Capeans Garrido, M. D. M.; Caprini, I.; Caprini, M.; Caprio, M.; Caracinha, D.; Caramarcu, C.; Carcagno, Y.; Cardarelli, R.; Cardeira, C.; Cardiel Sas, L.; Cardini, A.; Carli, T.; Carlino, G.; Carminati, L.; Caron, B.; Caron, S.; Carpentieri, C.; Carr, F. S.; Carter, A. A.; Carter, J. R.; Carvalho, J.; Casadei, D.; Casado, M. P.; Cascella, M.; Caso, C.; Castelo, J.; Castillo Gimenez, V.; Castro, N.; Castrovillari, F.; Cataldi, G.; Cataneo, F.; Catinaccio, A.; Catmore, J. R.; Cattai, A.; Caughron, S.; Cauz, D.; Cavallari, A.; Cavalleri, P.; Cavalli, D.; Cavalli-Sforza, M.; Cavasinni, V.; Ceradini, F.; Cerna, C.; Cernoch, C.; Cerqueira, A. S.; Cerri, A.; Cerutti, F.; Cervetto, M.; Cetin, S. A.; Cevenini, F.; Chalifour, M.; Chamizo llatas, M.; Chan, A.; Chapman, J. W.; Charlton, D. G.; Charron, S.; Chekulaev, S. V.; Chelkov, G. A.; Chen, H.; Chen, L.; Chen, T.; Chen, X.; Cheng, S.; Cheng, T. L.; Cheplakov, A.; Chepurnov, V. F.; Cherkaoui El Moursli, R.; Chesneanu, D.; Cheu, E.; Chevalier, L.; Chevalley, J. L.; Chevallier, F.; Chiarella, V.; Chiefari, G.; Chikovani, L.; Chilingarov, A.; Chiodini, G.; Chouridou, S.; Chren, D.; Christiansen, T.; Christidi, I. A.; Christov, A.; Chu, M. L.; Chudoba, J.; Chuguev, A. G.; Ciapetti, G.; Cicalini, E.; Ciftci, A. K.; Cindro, V.; Ciobotaru, M. D.; Ciocio, A.; Cirilli, M.; Citterio, M.; Ciubancan, M.; Civera, J. V.; Clark, A.; Cleland, W.; Clemens, J. C.; Clement, B. C.; Clément, C.; Clements, D.; Clifft, R. W.; Cobal, M.; Coccaro, A.; Cochran, J.; Coco, R.; Coe, P.; Coelli, S.; Cogneras, E.; Cojocaru, C. D.; Colas, J.; Colijn, A. P.; Collard, C.; Collins-Tooth, C.; Collot, J.; Coluccia, R.; Comune, G.; Conde Muiño, P.; Coniavitis, E.; Consonni, M.; Constantinescu, S.; Conta, C.; Conventi, F. A.; Cook, J.; Cooke, M.; Cooper-Smith, N. J.; Cornelissen, T.; Corradi, M.; Correard, S.; Corso-Radu, A.; Coss, J.; Costa, G.; Costa, M. J.; Costanzo, D.; Costin, T.; Coura Torres, R.; Courneyea, L.; Couyoumtzelis, C.; Cowan, G.; Cox, B. E.; Cox, J.; Cragg, D. A.; Cranmer, K.; Cranshaw, J.; Cristinziani, M.; Crosetti, G.; Cuenca Almenar, C.; Cuneo, S.; Cunha, A.; Curatolo, M.; Curtis, C. J.; Cwetanski, P.; Czyczula, Z.; D'Auria, S.; D'Onofrio, M.; Da Rocha Gesualdi Mello, A.; Da Silva, P. V. M.; Da Silva, R.; Dabrowski, W.; Dael, A.; Dahlhoff, A.; Dai, T.; Dallapiccola, C.; Dallison, S. J.; Dalmau, J.; Daly, C. H.; Dam, M.; Damazio, D.; Dameri, M.; Danielsen, K. M.; Danielsson, H. O.; Dankers, R.; Dannheim, D.; Darbo, G.; Dargent, P.; Daum, C.; Dauvergne, J. P.; David, M.; Davidek, T.; Davidson, N.; Davidson, R.; Dawson, I.; Dawson, J. W.; Daya, R. K.; De, K.; de Asmundis, R.; de Boer, R.; DeCastro, S.; DeGroot, N.; de Jong, P.; de La Broise, X.; DeLa Cruz-Burelo, E.; DeLa Taille, C.; DeLotto, B.; DeOliveira Branco, M.; DePedis, D.; de Saintignon, P.; DeSalvo, A.; DeSanctis, U.; DeSanto, A.; DeVivie DeRegie, J. B.; DeZorzi, G.; Dean, S.; Dedes, G.; Dedovich, D. V.; Defay, P. O.; Degele, R.; Dehchar, M.; Deile, M.; DelPapa, C.; DelPeso, J.; DelPrete, T.; Delagnes, E.; Delebecque, P.; Dell'Acqua, A.; Della Pietra, M.; della Volpe, D.; Delmastro, M.; Delpierre, P.; Delruelle, N.; Delsart, P. A.; Deluca Silberberg, C.; Demers, S.; Demichev, M.; Demierre, P.; Demirköz, B.; Deng, W.; Denisov, S. P.; Dennis, C.; Densham, C. J.; Dentan, M.; Derkaoui, J. E.; Derue, F.; Dervan, P.; Desch, K. K.; Dewhurst, A.; Di Ciaccio, A.; Di Ciaccio, L.; Di Domenico, A.; Di Girolamo, A.; Di Girolamo, B.; Di Luise, S.; Di Mattia, A.; Di Simone, A.; Diaz Gomez, M. M.; Diehl, E. B.; Dietl, H.; Dietrich, J.; Dietsche, W.; Diglio, S.; Dima, M.; Dindar, K.; Dinkespiler, B.; Dionisi, C.; Dipanjan, R.; Dita, P.; Dita, S.; Dittus, F.; Dixon, S. D.; Djama, F.; Djilkibaev, R.; Djobava, T.; do Vale, M. A. B.; Dobbs, M.; Dobinson, R.; Dobos, D.; Dobson, E.; Dobson, M.; Dodd, J.; Dogan, O. B.; Doherty, T.; Doi, Y.; Dolejsi, J.; Dolenc, I.; Dolezal, Z.; Dolgoshein, B. A.; Domingo, E.; Donega, M.; Dopke, J.; Dorfan, D. E.; Dorholt, O.; Doria, A.; Dos Anjos, A.; Dosil, M.; Dotti, A.; Dova, M. T.; Dowell, J. D.; Doyle, A. T.; Drake, G.; Drakoulakos, D.; Drasal, Z.; Drees, J.; Dressnandt, N.; Drevermann, H.; Driouichi, C.; Dris, M.; Drohan, J. G.; Dubbert, J.; Dubbs, T.; Duchovni, E.; Duckeck, G.; Dudarev, A.; Dührssen, M.; Dür, H.; Duerdoth, I. P.; Duffin, S.; Duflot, L.; Dufour, M.-A.; Dumont Dayot, N.; Duran Yildiz, H.; Durand, D.; Dushkin, A.; Duxfield, R.; Dwuznik, M.; Dydak, F.; Dzahini, D.; Díez Cornell, S.; Düren, M.; Ebenstein, W. L.; Eckert, S.; Eckweiler, S.; Eerola, P.; Efthymiopoulos, I.; Egede, U.; Egorov, K.; Ehrenfeld, W.; Eifert, T.; Eigen, G.; Einsweiler, K.; Eisenhandler, E.; Ekelof, T.; Eklund, L. M.; El Kacimi, M.; Ellert, M.; Elles, S.; Ellis, N.; Elmsheuser, J.; Elsing, M.; Ely, R.; Emeliyanov, D.; Engelmann, R.; Engström, M.; Ennes, P.; Epp, B.; Eppig, A.; Epshteyn, V. S.; Ereditato, A.; Eremin, V.; Eriksson, D.; Ermoline, I.; Ernwein, J.; Errede, D.; Errede, S.; Escalier, M.; Escobar, C.; Espinal Curull, X.; Esposito, B.; Esteves, F.; Etienne, F.; Etienvre, A. I.; Etzion, E.; Evans, H.; Evdokimov, V. N.; Evtoukhovitch, P.; Eyring, A.; Fabbri, L.; Fabjan, C. W.; Fabre, C.; Faccioli, P.; Facius, K.; Fadeyev, V.; Fakhrutdinov, R. M.; Falciano, S.; Falleau, I.; Falou, A. C.; Fang, Y.; Fanti, M.; Farbin, A.; Farilla, A.; Farrell, J.; Farthouat, P.; Fasching, D.; Fassi, F.; Fassnacht, P.; Fassouliotis, D.; Fawzi, F.; Fayard, L.; Fayette, F.; Febbraro, R.; Fedin, O. L.; Fedorko, I.; Feld, L.; Feldman, G.; Feligioni, L.; Feng, C.; Feng, E. J.; Fent, J.; Fenyuk, A. B.; Ferencei, J.; Ferguson, D.; Ferland, J.; Fernando, W.; Ferrag, S.; Ferrari, A.; Ferrari, P.; Ferrari, R.; Ferrer, A.; Ferrer, M. L.; Ferrere, D.; Ferretti, C.; Ferro, F.; Fiascaris, M.; Fichet, S.; Fiedler, F.; Filimonov, V.; Filipčič, A.; Filippas, A.; Filthaut, F.; Fincke-Keeler, M.; Finocchiaro, G.; Fiorini, L.; Firan, A.; Fischer, P.; Fisher, M. J.; Fisher, S. M.; Flaminio, V.; Flammer, J.; Flechl, M.; Fleck, I.; Flegel, W.; Fleischmann, P.; Fleischmann, S.; Fleta Corral, C. M.; Fleuret, F.; Flick, T.; Flix, J.; Flores Castillo, L. R.; Flowerdew, M. J.; Föhlisch, F.; Fokitis, M.; Fonseca Martin, T. M.; Fopma, J.; Forbush, D. A.; Formica, A.; Foster, J. M.; Fournier, D.; Foussat, A.; Fowler, A. J.; Fox, H.; Francavilla, P.; Francis, D.; Franz, S.; Fraser, J. T.; Fraternali, M.; Fratianni, S.; Freestone, J.; French, R. S.; Fritsch, K.; Froidevaux, D.; Frost, J. A.; Fukunaga, C.; Fulachier, J.; Fullana Torregrosa, E.; Fuster, J.; Gabaldon, C.; Gadomski, S.; Gagliardi, G.; Gagnon, P.; Gallas, E. J.; Gallas, M. V.; Gallop, B. J.; Gan, K. K.; Gannaway, F. C.; Gao, Y. S.; Gapienko, V. A.; Gaponenko, A.; Garciá, C.; Garcia-Sciveres, M.; Garcìa Navarro, J. E.; Garde, V.; Gardner, R. W.; Garelli, N.; Garitaonandia, H.; Garonne, V. G.; Garvey, J.; Gatti, C.; Gaudio, G.; Gaumer, O.; Gautard, V.; Gauzzi, P.; Gavrilenko, I. L.; Gay, C.; Gayde, J.-C.; Gazis, E. N.; Gazo, E.; Gee, C. N. P.; Geich-Gimbel, C.; Gellerstedt, K.; Gemme, C.; Genest, M. H.; Gentile, S.; George, M. A.; George, S.; Gerlach, P.; Gernizky, Y.; Geweniger, C.; Ghazlane, H.; Ghete, V. M.; Ghez, P.; Ghodbane, N.; Giacobbe, B.; Giagu, S.; Giakoumopoulou, V.; Giangiobbe, V.; Gianotti, F.; Gibbard, B.; Gibson, A.; Gibson, M. D.; Gibson, S. M.; Gieraltowski, G. F.; Gil Botella, I.; Gilbert, L. M.; Gilchriese, M.; Gildemeister, O.; Gilewsky, V.; Gillman, A. R.; Gingrich, D. M.; Ginzburg, J.; Giokaris, N.; Giordani, M. P.; Girard, C. G.; Giraud, P. F.; Girtler, P.; Giugni, D.; Giusti, P.; Gjelsten, B. K.; Glasman, C.; Glazov, A.; Glitza, K. W.; Glonti, G. L.; Gnanvo, K. G.; Godlewski, J.; Göpfert, T.; Gössling, C.; Göttfert, T.; Goldfarb, S.; Goldin, D.; Goldschmidt, N.; Golling, T.; Gollub, N. P.; Golonka, P. J.; Golovnia, S. N.; Gomes, A.; Gomes, J.; Gonçalo, R.; Gongadze, A.; Gonidec, A.; Gonzalez, S.; González de la Hoz, S.; González Millán, V.; Gonzalez Silva, M. L.; Gonzalez-Pineiro, B.; González-Sevilla, S.; Goodrick, M. J.; Goodson, J. J.; Goossens, L.; Gorbounov, P. A.; Gordeev, A.; Gordon, H.; Gorelov, I.; Gorfine, G.; Gorini, B.; Gorini, E.; Gorišek, A.; Gornicki, E.; Gorokhov, S. A.; Gorski, B. T.; Goryachev, S. V.; Goryachev, V. N.; Gosselink, M.; Gostkin, M. I.; Gouanère, M.; Gough Eschrich, I.; Goujdami, D.; Goulette, M.; Gousakov, I.; Gouveia, J.; Gowdy, S.; Goy, C.; Grabowska-Bold, I.; Grabski, V.; Grafström, P.; Grah, C.; Grahn, K.-J.; Grancagnolo, F.; Grancagnolo, S.; Grassmann, H.; Gratchev, V.; Gray, H. M.; Graziani, E.; Green, B.; Greenall, A.; Greenfield, D.; Greenwood, D.; Gregor, I. M.; Grewal, A.; Griesmayer, E.; Grigalashvili, N.; Grigson, C.; Grillo, A. A.; Grimaldi, F.; Grimm, K.; Gris, P. L. Y.; Grishkevich, Y.; Groenstege, H.; Groer, L. S.; Grognuz, J.; Groh, M.; Gross, E.; Grosse-Knetter, J.; Grothe, M. E. M.; Grudzinski, J.; Gruse, C.; Gruwe, M.; Grybel, K.; Grybos, P.; Gschwendtner, E. M.; Guarino, V. J.; Guicheney, C. J.; Guilhem, G.; Guillemin, T.; Gunther, J.; Guo, B.; Gupta, A.; Gurriana, L.; Gushchin, V. N.; Gutierrez, P.; Guy, L.; Guyot, C.; Gwenlan, C.; Gwilliam, C. B.; Haas, A.; Haas, S.; Haber, C.; Haboubi, G.; Hackenburg, R.; Hadash, E.; Hadavand, H. K.; Haeberli, C.; Härtel, R.; Haggerty, R.; Hahn, F.; Haider, S.; Hajduk, Z.; Hakimi, M.; Hakobyan, H.; Hakobyan, H.; Haller, J.; Hallewell, G. D.; Hallgren, B.; Hamacher, K.; Hamilton, A.; Han, H.; Han, L.; Hanagaki, K.; Hance, M.; Hanke, P.; Hansen, C. J.; Hansen, F. H.; Hansen, J. R.; Hansen, J. B.; Hansen, J. D.; Hansen, P. H.; Hansl-Kozanecka, T.; Hanson, G.; Hansson, P.; Hara, K.; Harder, S.; Harel, A.; Harenberg, T.; Harper, R.; Hart, J. C.; Hart, R. G. G.; Hartjes, F.; Hartman, N.; Haruyama, T.; Harvey, A.; Hasegawa, Y.; Hashemi, K.; Hassani, S.; Hatch, M.; Hatley, R. W.; Haubold, T. G.; Hauff, D.; Haug, F.; Haug, S.; Hauschild, M.; Hauser, R.; Hauviller, C.; Havranek, M.; Hawes, B. M.; Hawkings, R. J.; Hawkins, D.; Hayler, T.; Hayward, H. S.; Haywood, S. J.; Hazen, E.; He, M.; He, Y. P.; Head, S. J.; Hedberg, V.; Heelan, L.; Heinemann, F. E. W.; Heldmann, M.; Hellman, S.; Helsens, C.; Henderson, R. C. W.; Hendriks, P. J.; Henriques Correia, A. M.; Henrot-Versille, S.; Henry-Couannier, F.; Henß, T.; Herten, G.; Hertenberger, R.; Hervas, L.; Hess, M.; Hessey, N. P.; Hicheur, A.; Hidvegi, A.; Higón-Rodriguez, E.; Hill, D.; Hill, J.; Hill, J. C.; Hill, N.; Hillier, S. J.; Hinchliffe, I.; Hindson, D.; Hinkelbein, C.; Hodges, T. A.; Hodgkinson, M. C.; Hodgson, P.; Hoecker, A.; Hoeferkamp, M. R.; Hoffman, J.; Hoffmann, A. E.; Hoffmann, D.; Hoffmann, H. F.; Holder, M.; Hollins, T. I.; Hollyman, G.; Holmes, A.; Holmgren, S. O.; Holt, R.; Holtom, E.; Holy, T.; Homer, R. J.; Homma, Y.; Homola, P.; Honerbach, W.; Honma, A.; Hooton, I.; Horazdovsky, T.; Horn, C.; Horvat, S.; Hostachy, J.-Y.; Hott, T.; Hou, S.; Houlden, M. A.; Hoummada, A.; Hover, J.; Howell, D. F.; Hrivnac, J.; Hruska, I.; Hryn'ova, T.; Huang, G. S.; Hubacek, Z.; Hubaut, F.; Huegging, F.; Huffman, B. T.; Hughes, E.; Hughes, G.; Hughes-Jones, R. E.; Hulsbergen, W.; Hurst, P.; Hurwitz, M.; Huse, T.; Huseynov, N.; Huston, J.; Huth, J.; Iacobucci, G.; Ibbotson, M.; Ibragimov, I.; Ichimiya, R.; Iconomidou-Fayard, L.; Idarraga, J.; Idzik, M.; Iengo, P.; Iglesias Escudero, M. C.; Igonkina, O.; Ikegami, Y.; Ikeno, M.; Ilchenko, Y.; Ilyushenka, Y.; Imbault, D.; Imbert, P.; Imhaeuser, M.; Imori, M.; Ince, T.; Inigo-Golfin, J.; Inoue, K.; Ioannou, P.; Iodice, M.; Ionescu, G.; Ishii, K.; Ishino, M.; Ishizawa, Y.; Ishmukhametov, R.; Issever, C.; Ito, H.; Ivashin, A. V.; Iwanski, W.; Iwasaki, H.; Izen, J. M.; Izzo, V.; Jackson, J.; Jackson, J. N.; Jaekel, M.; Jagielski, S.; Jahoda, M.; Jain, V.; Jakobs, K.; Jakubek, J.; Jansen, E.; Jansweijer, P. P. M.; Jared, R. C.; Jarlskog, G.; Jarp, S.; Jarron, P.; Jelen, K.; Jen-La Plante, I.; Jenni, P.; Jeremie, A.; Jez, P.; Jézéquel, S.; Jiang, Y.; Jin, G.; Jin, S.; Jinnouchi, O.; Joffe, D.; Johansen, L. G.; Johansen, M.; Johansson, K. E.; Johansson, P.; Johns, K. A.; Jon-And, K.; Jones, M.; Jones, R.; Jones, R. W. L.; Jones, T. W.; Jones, T. J.; Jones, A.; Jonsson, O.; Joo, K. K.; Joos, D.; Joos, M.; Joram, C.; Jorgensen, S.; Joseph, J.; Jovanovic, P.; Junnarkar, S. S.; Juranek, V.; Jussel, P.; Kabachenko, V. V.; Kabana, S.; Kaci, M.; Kaczmarska, A.; Kado, M.; Kagan, H.; Kagawa, S.; Kaiser, S.; Kajomovitz, E.; Kakurin, S.; Kalinovskaya, L. V.; Kama, S.; Kambara, H.; Kanaya, N.; Kandasamy, A.; Kandasamy, S.; Kaneda, M.; Kantserov, V. A.; Kanzaki, J.; Kaplan, B.; Kapliy, A.; Kaplon, J.; Karagounis, M.; Karagoz Unel, M.; Karr, K.; Karst, P.; Kartvelishvili, V.; Karyukhin, A. N.; Kashif, L.; Kasmi, A.; Kass, R. D.; Kastanas, A.; Kataoka, M.; Kataoka, Y.; Katsoufis, E.; Katunin, S.; Kawagoe, K.; Kawai, M.; Kawamoto, T.; Kayumov, F.; Kazanin, V. A.; Kazarinov, M. Y.; Kazarov, A.; Kazi, S. I.; Keates, J. R.; Keeler, R.; Keener, P. T.; Kehoe, R.; Keil, M.; Kekelidze, G. D.; Kelly, M.; Kennedy, J.; Kenyon, M.; Kepka, O.; Kerschen, N.; Kerševan, B. P.; Kersten, S.; Ketterer, C.; Khakzad, M.; Khalilzade, F.; Khandanyan, H.; Khanov, A.; Kharchenko, D.; Khodinov, A.; Kholodenko, A. G.; Khomich, A.; Khomutnikov, V. P.; Khoriauli, G.; Khovanskiy, N.; Khovanskiy, V.; Khramov, E.; Khubua, J.; Kieft, G.; Kierstead, J. A.; Kilvington, G.; Kim, H.; Kim, H.; Kim, S. H.; Kind, P.; King, B. T.; Kirk, J.; Kirsch, G. P.; Kirsch, L. E.; Kiryunin, A. E.; Kisielewska, D.; Kisielewski, B.; Kittelmann, T.; Kiver, A. M.; Kiyamura, H.; Kladiva, E.; Klaiber-Lodewigs, J.; Kleinknecht, K.; Klier, A.; Klimentov, A.; Kline, C. R.; Klingenberg, R.; Klinkby, E. B.; Klioutchnikova, T.; Klok, P. F.; Klous, S.; Kluge, E.-E.; Kluit, P.; Klute, M.; Kluth, S.; Knecht, N. K.; Kneringer, E.; Knezo, E.; Knobloch, J.; Ko, B. R.; Kobayashi, T.; Kobel, M.; Kodys, P.; König, A. C.; König, S.; Köpke, L.; Koetsveld, F.; Koffas, T.; Koffeman, E.; Kohout, Z.; Kohriki, T.; Kokott, T.; Kolachev, G. M.; Kolanoski, H.; Kolesnikov, V.; Koletsou, I.; Kollefrath, M.; Kolos, S.; Kolya, S. D.; Komar, A. A.; Komaragiri, J. R.; Kondo, T.; Kondo, Y.; Kondratyeva, N. V.; Kono, T.; Kononov, A. I.; Konoplich, R.; Konovalov, S. P.; Konstantinidis, N.; Kootz, A.; Koperny, S.; Kopikov, S. V.; Korcyl, K.; Kordas, K.; Koreshev, V.; Korn, A.; Korolkov, I.; Korotkov, V. A.; Korsmo, H.; Kortner, O.; Kostrikov, M. E.; Kostyukhin, V. V.; Kotamäki, M. J.; Kotchetkov, D.; Kotov, S.; Kotov, V. M.; Kotov, K. Y.; Kourkoumelis, C.; Koutsman, A.; Kovalenko, S.; Kowalewski, R.; Kowalski, H.; Kowalski, T. Z.; Kozanecki, W.; Kozhin, A. S.; Kral, V.; Kramarenko, V.; Kramberger, G.; Kramer, A.; Krasel, O.; Krasny, M. W.; Krasznahorkay, A.; Krepouri, A.; Krieger, P.; Krivkova, P.; Krobath, G.; Kroha, H.; Krstic, J.; Kruchonak, U.; Krüger, H.; Kruger, K.; Krumshteyn, Z. V.; Kubik, P.; Kubischta, W.; Kubota, T.; Kudin, L. G.; Kudlaty, J.; Kugel, A.; Kuhl, T.; Kuhn, D.; Kukhtin, V.; Kulchitsky, Y.; Kundu, N.; Kupco, A.; Kupper, M.; Kurashige, H.; Kurchaninov, L. L.; Kurochkin, Y. A.; Kus, V.; Kuykendall, W.; Kuzhir, P.; Kuznetsova, E. K.; Kvasnicka, O.; Kwee, R.; La Marra, D.; La Rosa, M.; La Rotonda, L.; Labarga, L.; Labbe, J. A.; Lacasta, C.; Lacava, F.; Lacker, H.; Lacour, D.; Lacuesta, V. R.; Ladygin, E.; Lafaye, R.; Laforge, B.; Lagouri, T.; Lai, S.; Lamanna, E.; Lambacher, M.; Lambert, F.; Lampl, W.; Lancon, E.; Landgraf, U.; Landon, M. P. J.; Landsman, H.; Langstaff, R. R.; Lankford, A. J.; Lanni, F.; Lantzsch, K.; Lanza, A.; Lapin, V. V.; Laplace, S.; Laporte, J. F.; Lara, V.; Lari, T.; Larionov, A. V.; Lasseur, C.; Lau, W.; Laurelli, P.; Lavorato, A.; Lavrijsen, W.; Lazarev, A. B.; LeBihan, A.-C.; LeDortz, O.; LeManer, C.; LeVine, M.; Leahu, L.; Leahu, M.; Lebel, C.; Lechowski, M.; LeCompte, T.; Ledroit-Guillon, F.; Lee, H.; Lee, J. S. H.; Lee, S. C.; Lefebvre, M.; Lefevre, R. P.; Legendre, M.; Leger, A.; LeGeyt, B. C.; Leggett, C.; Lehmacher, M.; Lehmann Miotto, G.; Lehto, M.; Leitner, R.; Lelas, D.; Lellouch, D.; Leltchouk, M.; Lendermann, V.; Leney, K. J. C.; Lenz, T.; Lenzen, G.; Lepidis, J.; Leroy, C.; Lessard, J.-R.; Lesser, J.; Lester, C. G.; Letheren, M.; Fook Cheong, A. Leung; Levêque, J.; Levin, D.; Levinson, L. J.; Levitski, M. S.; Lewandowska, M.; Leyton, M.; Li, J.; Li, W.; Liabline, M.; Liang, Z.; Liang, Z.; Liberti, B.; Lichard, P.; Liebig, W.; Lifshitz, R.; Liko, D.; Lim, H.; Limper, M.; Lin, S. C.; Lindahl, A.; Linde, F.; Lindquist, L.; Lindsay, S. W.; Linhart, V.; Lintern, A. J.; Liolios, A.; Lipniacka, A.; Liss, T. M.; Lissauer, A.; List, J.; Litke, A. M.; Liu, S.; Liu, T.; Liu, Y.; Livan, M.; Lleres, A.; Llosá Llácer, G.; Lloyd, S. L.; Lobkowicz, F.; Loch, P.; Lockman, W. S.; Loddenkoetter, T.; Loebinger, F. K.; Loginov, A.; Loh, C. W.; Lohse, T.; Lohwasser, K.; Lokajicek, M.; Loken, J.; Lokwitz, S.; Long, M. C.; Lopes, L.; Lopez Mateos, D.; Losty, M. J.; Lou, X.; Loureiro, K. F.; Lovas, L.; Love, J.; Lowe, A.; Lozano Fantoba, M.; Lu, F.; Lu, J.; Lu, L.; Lubatti, H. J.; Lucas, S.; Luci, C.; Lucotte, A.; Ludwig, A.; Ludwig, I.; Ludwig, J.; Luehring, F.; Lüke, D.; Luijckx, G.; Luisa, L.; Lumb, D.; Luminari, L.; Lund, E.; Lund-Jensen, B.; Lundberg, B.; Lundquist, J.; Lupi, A.; Lupu, N.; Lutz, G.; Lynn, D.; Lynn, J.; Lys, J.; Lysan, V.; Lytken, E.; López-Amengual, J. M.; Ma, H.; Ma, L. L.; Maaß en, M.; Maccarrone, G.; Mace, G. G. R.; Macina, D.; Mackeprang, R.; Macpherson, A.; MacQueen, D.; Macwaters, C.; Madaras, R. J.; Mader, W. F.; Maenner, R.; Maeno, T.; Mättig, P.; Mättig, S.; Magrath, C. A.; Mahalalel, Y.; Mahboubi, K.; Mahout, G.; Maidantchik, C.; Maio, A.; Mair, G. M.; Mair, K.; Makida, Y.; Makowiecki, D.; Malecki, P.; Maleev, V. P.; Malek, F.; Malon, D.; Maltezos, S.; Malychev, V.; Malyukov, S.; Mambelli, M.; Mameghani, R.; Mamuzic, J.; Manabe, A.; Manara, A.; Manca, G.; Mandelli, L.; Mandić, I.; Mandl, M.; Maneira, J.; Maneira, M.; Mangeard, P. S.; Mangin-Brinet, M.; Manjavidze, I. D.; Mann, W. A.; Manolopoulos, S.; Manousakis-Katsikakis, A.; Mansoulie, B.; Manz, A.; Mapelli, A.; Mapelli, L.; March, L.; Marchand, J. F.; Marchesotti, M.; Marcisovsky, M.; Marin, A.; Marques, C. N.; Marroquim, F.; Marshall, R.; Marshall, Z.; Martens, F. K.; Garcia, S. Marti i.; Martin, A. J.; Martin, B.; Martin, B.; Martin, F. F.; Martin, J. P.; Martin, Ph; Martinez, G.; Martínez Lacambra, C.; Martinez Outschoorn, V.; Martini, A.; Martins, J.; Maruyama, T.; Marzano, F.; Mashimo, T.; Mashinistov, R.; Masik, J.; Maslennikov, A. L.; Maß, M.; Massa, I.; Massaro, G.; Massol, N.; Mathes, M.; Matheson, J.; Matricon, P.; Matsumoto, H.; Matsunaga, H.; Maugain, J. M.; Maxfield, S. J.; May, E. N.; Mayer, J. K.; Mayri, C.; Mazini, R.; Mazzanti, M.; Mazzanti, P.; Mazzoni, E.; Mazzucato, F.; McKee, S. P.; McCarthy, R. L.; McCormick, C.; McCubbin, N. A.; McDonald, J.; McFarlane, K. W.; McGarvie, S.; McGlone, H.; McLaren, R. A.; McMahon, S. J.; McMahon, T. R.; McMahon, T. J.; McPherson, R. A.; Mechtel, M.; Meder-Marouelli, D.; Medinnis, M.; Meera-Lebbai, R.; Meessen, C.; Mehdiyev, R.; Mehta, A.; Meier, K.; Meinhard, H.; Meinhardt, J.; Meirosu, C.; Meisel, F.; Melamed-Katz, A.; Mellado Garcia, B. R.; Mendes Jorge, P.; Mendez, P.; Menke, S.; Menot, C.; Meoni, E.; Merkl, D.; Merola, L.; Meroni, C.; Merritt, F. S.; Messmer, I.; Metcalfe, J.; Meuser, S.; Meyer, J.-P.; Meyer, T. C.; Meyer, W. T.; Mialkovski, V.; Michelotto, M.; Micu, L.; Middleton, R.; Miele, P.; Migliaccio, A.; Mijović, L.; Mikenberg, G.; Mikestikova, M.; Mikestikova, M.; Mikulec, B.; Mikuž, M.; Miller, D. W.; Miller, R. J.; Miller, W.; Milosavljevic, M.; Milstead, D. A.; Mima, S.; Minaenko, A. A.; Minano, M.; Minashvili, I. A.; Mincer, A. I.; Mindur, B.; Mineev, M.; Mir, L. M.; Mirabelli, G.; Miralles Verge, L.; Misawa, S.; Miscetti, S.; Misiejuk, A.; Mitra, A.; Mitrofanov, G. Y.; Mitsou, V. A.; Miyagawa, P. S.; Miyazaki, Y.; Mjörnmark, J. U.; Mkrtchyan, S.; Mladenov, D.; Moa, T.; Moch, M.; Mochizuki, A.; Mockett, P.; Modesto, P.; Moed, S.; Mönig, K.; Möser, N.; Mohn, B.; Mohr, W.; Mohrdieck-Möck, S.; Moisseev, A. M.; Moles Valls, R. M.; Molina-Perez, J.; Moll, A.; Moloney, G.; Mommsen, R.; Moneta, L.; Monnier, E.; Montarou, G.; Montesano, S.; Monticelli, F.; Moore, R. W.; Moore, T. B.; Moorhead, G. F.; Moraes, A.; Morel, J.; Moreno, A.; Moreno, D.; Morettini, P.; Morgan, D.; Morii, M.; Morin, J.; Morley, A. K.; Mornacchi, G.; Morone, M.-C.; Morozov, S. V.; Morris, E. J.; Morris, J.; Morrissey, M. C.; Moser, H. G.; Mosidze, M.; Moszczynski, A.; Mouraviev, S. V.; Mouthuy, T.; Moye, T. H.; Moyse, E. J. W.; Mueller, J.; Müller, M.; Muijs, A.; Muller, T. R.; Munar, A.; Munday, D. J.; Murakami, K.; Murillo Garcia, R.; Murray, W. J.; Myagkov, A. G.; Myska, M.; Nagai, K.; Nagai, Y.; Nagano, K.; Nagasaka, Y.; Nairz, A. M.; Naito, D.; Nakamura, K.; Nakamura, Y.; Nakano, I.; Nanava, G.; Napier, A.; Nassiakou, M.; Nasteva, I.; Nation, N. R.; Naumann, T.; Nauyock, F.; Nderitu, S. K.; Neal, H. A.; Nebot, E.; Nechaeva, P.; Neganov, A.; Negri, A.; Negroni, S.; Nelson, C.; Nemecek, S.; Nemethy, P.; Nepomuceno, A. A.; Nessi, M.; Nesterov, S. Y.; Neukermans, L.; Nevski, P.; Newcomer, F. M.; Nichols, A.; Nicholson, C.; Nicholson, R.; Nickerson, R. B.; Nicolaidou, R.; Nicoletti, G.; Nicquevert, B.; Niculescu, M.; Nielsen, J.; Niinikoski, T.; Niinimaki, M. J.; Nikitin, N.; Nikolaev, K.; Nikolic-Audit, I.; Nikolopoulos, K.; Nilsen, H.; Nilsson, B. S.; Nilsson, P.; Nisati, A.; Nisius, R.; Nodulman, L. J.; Nomachi, M.; Nomoto, H.; Noppe, J.-M.; Nordberg, M.; Norniella Francisco, O.; Norton, P. R.; Novakova, J.; Nowak, M.; Nozaki, M.; Nunes, R.; Nunes Hanninger, G.; Nunnemann, T.; Nyman, T.; O'Connor, P.; O'Neale, S. W.; O'Neil, D. C.; O'Neill, M.; O'Shea, V.; Oakham, F. G.; Oberlack, H.; Obermaier, M.; Oberson, P.; Ochi, A.; Ockenfels, W.; Odaka, S.; Odenthal, I.; Odino, G. A.; Ogren, H.; Oh, S. H.; Ohshima, T.; Ohshita, H.; Okawa, H.; Olcese, M.; Olchevski, A. G.; Oliver, C.; Oliver, J.; Olivo Gomez, M.; Olszewski, A.; Olszowska, J.; Omachi, C.; Onea, A.; Onofre, A.; Oram, C. J.; Ordonez, G.; Oreglia, M. J.; Orellana, F.; Oren, Y.; Orestano, D.; Orlov, I. O.; Orr, R. S.; Orsini, F.; Osborne, L. S.; Osculati, B.; Osuna, C.; Otec, R.; Othegraven, R.; Ottewell, B.; Ould-Saada, F.; Ouraou, A.; Ouyang, Q.; Øye, O. K.; Ozcan, V. E.; Ozone, K.; Ozturk, N.; Pacheco Pages, A.; Padhi, S.; Padilla Aranda, C.; Paganis, E.; Paige, F.; Pailler, P. M.; Pajchel, K.; Palestini, S.; Palla, J.; Pallin, D.; Palmer, M. J.; Pan, Y. B.; Panikashvili, N.; Panin, V. N.; Panitkin, S.; Pantea, D.; Panuskova, M.; Paolone, V.; Paoloni, A.; Papadopoulos, I.; Papadopoulou, T.; Park, I.; Park, W.; Parker, M. A.; Parker, S.; Parkman, C.; Parodi, F.; Parsons, J. A.; Parzefall, U.; Pasqualucci, E.; Passardi, G.; Passeri, A.; Passmore, M. S.; Pastore, F.; Pastore, Fr; Pataraia, S.; Pate, D.; Pater, J. R.; Patricelli, S.; Pauly, T.; Pauna, E.; Peak, L. S.; Peeters, S. J. M.; Peez, M.; Pei, E.; Peleganchuk, S. V.; Pellegrini, G.; Pengo, R.; Pequenao, J.; Perantoni, M.; Perazzo, A.; Pereira, A.; Perepelkin, E.; Perera, V. J. O.; Perez Codina, E.; Perez Reale, V.; Peric, I.; Perini, L.; Pernegger, H.; Perrin, E.; Perrino, R.; Perrodo, P.; Perrot, G.; Perus, P.; Peshekhonov, V. D.; Petereit, E.; Petersen, J.; Petersen, T. C.; Petit, P. J. F.; Petridou, C.; Petrolo, E.; Petrucci, F.; Petti, R.; Pezzetti, M.; Pfeifer, B.; Phan, A.; Phillips, A. W.; Phillips, P. W.; Piacquadio, G.; Piccinini, M.; Pickford, A.; Piegaia, R.; Pier, S.; Pilcher, J. E.; Pilkington, A. D.; Pimenta Dos Santos, M. A.; Pina, J.; Pinfold, J. L.; Ping, J.; Pinhão, J.; Pinto, B.; Pirotte, O.; Placakyte, R.; Placci, A.; Plamondon, M.; Plano, W. G.; Pleier, M.-A.; Pleskach, A. V.; Podkladkin, S.; Podlyski, F.; Poffenberger, P.; Poggioli, L.; Pohl, M.; Polak, I.; Polesello, G.; Policicchio, A.; Polini, A.; Polychronakos, V.; Pomarede, D. M.; Pommès, K.; Ponsot, P.; Pontecorvo, L.; Pope, B. G.; Popescu, R.; Popovic, D. S.; Poppleton, A.; Popule, J.; Portell Bueso, X.; Posch, C.; Pospelov, G. E.; Pospichal, P.; Pospisil, S.; Postranecky, M.; Potrap, I. N.; Potter, C. J.; Poulard, G.; Pousada, A.; Poveda, J.; Prabhu, R.; Pralavorio, P.; Prasad, S.; Prast, J.; Prat, S.; Prata, M.; Pravahan, R.; Preda, T.; Pretzl, K.; Pribyl, L.; Price, D.; Price, L. E.; Price, M. J.; Prichard, P. M.; Prieur, D.; Primavera, M.; Primor, D.; Prokofiev, K.; Prosso, E.; Proudfoot, J.; Przysiezniak, H.; Puigdengoles, C.; Purdham, J.; Purohit, M.; Puzo, P.; Pylaev, A. N.; Pylypchenko, Y.; Qi, M.; Qian, J.; Qian, W.; Qian, Z.; Qing, D.; Quadt, A.; Quarrie, D. R.; Quayle, W. B.; Rabbers, J. J.; Radeka, V.; Rafi, J. M.; Ragusa, F.; Rahimi, A. M.; Rahm, D.; Raine, C.; Raith, B.; Rajagopalan, S.; Rajek, S.; Rammer, H.; Ramstedt, M.; Rangod, S.; Ratoff, P. N.; Raufer, T.; Rauscher, F.; Rauter, E.; Raymond, M.; Reads, A. L.; Rebuzzi, D.; Redlinger, G. R.; Reeves, K.; Rehak, M.; Reichold, A.; Reinherz-Aronis, E.; Reisinger, I.; Reljic, D.; Rembser, C.; Ren, Z.; Renaudin-Crepe, S. R. C.; Renkel, P.; Rensch, B.; Rescia, S.; Rescigno, M.; Resconi, S.; Resende, B.; Rewiersma, P.; Rey, J.; Rey-Campagnolle, M.; Rezaie, E.; Reznicek, P.; Richards, R. A.; Richer, J.-P.; Richter, R. H.; Richter, R.; Richter-Was, E.; Ridel, M.; Riegler, W.; Rieke, S.; Rijpstra, M.; Rijssenbeek, M.; Rimoldi, A.; Rios, R. R.; Riu Dachs, I.; Rivline, M.; Rivoltella, G.; Rizatdinova, F.; Robertson, S. H.; Robichaud-Veronneau, A.; Robins, S.; Robinson, D.; Robson, A.; Rochford, J. H.; Roda, C.; Rodier, S.; Roe, S.; Røhne, O.; Rohrbach, F.; Roldán, J.; Rolli, S.; Romance, J. B.; Romaniouk, A.; Romanov, V. M.; Romeo, G.; Roos, L.; Ros, E.; Rosati, S.; Rosenbaum, F.; Rosenbaum, G. A.; Rosenberg, E. I.; Rosselet, L.; Rossi, L. P.; Rossi, L.; Rotaru, M.; Rothberg, J.; Rottländer, I.; Rousseau, D.; Rozanov, A.; Rozen, Y.; Ruber, R.; Ruckert, B.; Rudolph, G.; Rühr, F.; Ruggieri, F.; Ruggiero, G.; Ruiz, H.; Ruiz-Martinez, A.; Rulikowska-Zarebska, E.; Rumiantsev, V.; Rumyantsev, L.; Runge, K.; Runolfsson, O.; Rusakovich, N. A.; Rust, D. R.; Rutherfoord, J. P.; Ruwiedel, C.; Ryabov, Y. F.; Ryadovikov, V.; Ryan, P.; Rybkine, G.; da Costa, J. Sá; Saavedra, A. F.; Saboumazrag, S.; F-W Sadrozinski, H.; Sadykov, R.; Sakamoto, H.; Sala, P.; Salamon, A.; Saleem, M.; Salihagic, D.; Salt, J.; Saltó Bauza, O.; Salvachúa Ferrando, B. M.; Salvatore, D.; Salzburger, A.; Sampsonidis, D.; Samset, B. H.; Sánchez Sánchez, C. A.; Sanchis Lozano, M. A.; Sanchis Peris, E.; Sandaker, H.; Sander, H. G.; Sandhoff, M.; Sandvoss, S.; Sankey, D. P. C.; Sanny, B.; Sansone, S.; Sansoni, A.; Santamarina Rios, C.; Santander, J.; Santi, L.; Santoni, C.; Santonico, R.; Santos, J.; Sapinski, M.; Saraiva, J. G.; Sarri, F.; Sasaki, O.; Sasaki, T.; Sasao, N.; Satsounkevitch, I.; Sauvage, D.; Sauvage, G.; Savard, P.; Savine, A. Y.; Savinov, V.; Savoy-Navarro, A.; Savva, P.; Saxon, D. H.; Says, L. P.; Sbarra, C.; Sbrissa, E.; Sbrizzi, A.; Scannicchio, D. A.; Schaarschmidt, J.; Schacht, P.; Schäfer, U.; Schaffer, A. C.; Schaile, D.; Schaller, M.; Schamov, A. G.; Schegelsky, V. A.; Scheirich, D.; Schernau, M.; Scherzer, M. I.; Schiavi, C.; Schick, H.; Schieck, J.; Schieferdecker, P.; Schioppa, M.; Schlager, G.; Schlenker, S.; Schlereth, J. L.; Schmid, P.; Schmidt, M. P.; Schmitt, C.; Schmitt, K.; Schmitz, M.; Schmücker, H.; Schoerner, T.; Scholte, R. C.; Schott, M.; Schouten, D.; Schram, M.; Schricker, A.; Schroff, D.; Schuh, S.; Schuijlenburg, H. W.; Schuler, G.; Schultes, J.; Schultz-Coulon, H.-C.; Schumacher, J.; Schumacher, M.; Schune, Ph; Schwartzman, A.; Schweiger, D.; Schwemling, Ph; Schwick, C.; Schwienhorst, R.; Schwierz, R.; Schwindling, J.; Scott, W. G.; Secker, H.; Sedykh, E.; Seguin-Moreau, N.; Segura, E.; Seidel, S. C.; Seiden, A.; Seixas, J. M.; Sekhniaidze, G.; Seliverstov, D. M.; Selldén, B.; Seman, M.; Semprini-Cesari, N.; Serfon, C.; Serin, L.; Seuster, R.; Severini, H.; Sevior, M. E.; Sexton, K. A.; Sfyrla, A.; Shah, T. P.; Shan, L.; Shank, J. T.; Shapiro, M.; Shatalov, P. B.; Shaver, L.; Shaw, C.; Shears, T. G.; Sherwood, P.; Shibata, A.; Shield, P.; Shilov, S.; Shimojima, M.; Shin, T.; Shiyakova, M.; Shmeleva, A.; Shoa, M.; Shochet, M. J.; Shupe, M. A.; Sicho, P.; Sidoti, A.; Siebel, A.; Siebel, M.; Siegrist, J.; Sijacki, D.; Silva, J.; Silverstein, S. B.; Simak, V.; Simic, Lj; Simion, S.; Simmons, B.; Simonyan, M.; Sinervo, P.; Sipica, V.; Siragusa, G.; Sisakyan, A. N.; Sivoklokov, S.; Sjölin, J.; Skubic, P.; Skvorodnev, N.; Slattery, P.; Slavicek, T.; Sliwa, K.; Sloan, T. J.; Sloper, J.; Smakhtin, V.; Small, A.; Smirnov, S. Yu; Smirnov, Y.; Smirnova, L.; Smirnova, O.; Smith, N. A.; Smith, B. C.; Smith, D. S.; Smith, J.; Smith, K. M.; Smith, B.; Smizanska, M.; Smolek, K.; Snesarev, A. A.; Snow, S. W.; Snow, J.; Snuverink, J.; Snyder, S.; Soares, M.; Soares, S.; Sobie, R.; Sodomka, J.; Söderberg, M.; Soffer, A.; Solans, C. A.; Solar, M.; Sole, D.; Solfaroli Camillocci, E.; Solodkov, A. A.; Solov'yanov, O. V.; Soloviev, I.; Soluk, R.; Sondericker, J.; Sopko, V.; Sopko, B.; Sorbi, M.; Soret Medel, J.; Sosebee, M.; Sosnovtsev, V. V.; Sospedra Suay, L.; Soukharev, A.; Soukup, J.; Spagnolo, S.; Spano, F.; Speckmayer, P.; Spegel, M.; Spencer, E.; Spighi, R.; Spigo, G.; Spila, F.; Spiriti, E.; Spiwoks, R.; Spogli, L.; Spousta, M.; Sprachmann, G.; Spurlock, B.; St. Denis, R. D.; Stahl, T.; Staley, R. J.; Stamen, R.; Stancu, S. N.; Stanecka, E.; Stanek, R. W.; Stanescu, C.; Stapnes, S.; Starchenko, E. A.; Staroba, P.; Stastny, J.; Staude, A.; Stavina, P.; Stavrianakou, M.; Stavropoulos, G.; Stefanidis, E.; Steffens, J. L.; Stekl, I.; Stelzer, H. J.; Stenzel, H.; Stewart, G.; Stewart, T. D.; Stiller, W.; Stockmanns, T.; Stodulski, M.; Stonjek, S.; Stradling, A.; Straessner, A.; Strandberg, J.; Strandlie, A.; Strauss, M.; Strickland, V.; Striegel, D.; Strizenec, P.; Ströhmer, R.; Strom, D. M.; Strong, J. A.; Stroynowski, R.; Stugu, B.; Stumer, I.; Su, D.; Subramania, S.; Suchkov, S. I.; Sugaya, Y.; Sugimoto, T.; Suk, M.; Sulin, V. V.; Sultanov, S.; Sun, Z.; Sundal, B.; Sushkov, S.; Susinno, G.; Sutcliffe, P.; Sutton, M. R.; Sviridov, Yu M.; Sykora, I.; Szczygiel, R. R.; Szeless, B.; Szymocha, T.; Sánchez, J.; Ta, D.; Taboada Gameiro, S.; Tadel, M.; Tafirout, R.; Taga, A.; Takai, H.; Takashima, R.; Takeda, H.; Takeshita, T.; Talby, M.; Talyshev, A.; Tamsett, M. C.; Tanaka, J.; Tanaka, K.; Tanaka, R.; Tanaka, S.; Tanaka, S.; Tanaka, Y.; Tappern, G. P.; Tapprogge, S.; Tarem, S.; Tarrade, F.; Tarrant, J.; Tartarelli, G.; Tas, P.; Tasevsky, M.; Tayalati, Y.; Taylor, F. E.; Taylor, G.; Taylor, G. N.; Taylor, R. P.; Tcherniatine, V.; Tegenfeldt, F.; Teixeira-Dias, P.; Ten Kate, H.; Teng, P. K.; Ter-Antonyan, R.; Terada, S.; Terron, J.; Terwort, M.; Teuscher, R. J.; Tevlin, C. M.; Thadome, J.; Thion, J.; Thioye, M.; Thomas, A.; Thomas, J. P.; Thomas, T. L.; Thomas, E.; Thompson, R. J.; Thompson, A. S.; Thun, R. P.; Tic, T.; Tikhomirov, V. O.; Tikhonov, Y. A.; Timm, S.; Timmermans, C. J. W. P.; Tipton, P.; Tique Aires Viegas, F. J.; Tisserant, S.; Titov, M.; Tobias, J.; Tocut, V. M.; Toczek, B.; Todorova-Nova, S.; Tojo, J.; Tokár, S.; Tokushuku, K.; Tomasek, L.; Tomasek, M.; Tomasz, F.; Tomoto, M.; Tompkins, D.; Tompkins, L.; Toms, K.; Tonazzo, A.; Tong, G.; Tonoyan, A.; Topfel, C.; Topilin, N. D.; Torrence, E.; Torres Pais, J. G.; Toth, J.; Touchard, F.; Tovey, D. R.; Tovey, S. N.; Towndrow, E. F.; Trefzger, T.; Treichel, M.; Treis, J.; Tremblet, L.; Tribanek, W.; Tricoli, A.; Trigger, I. M.; Trilling, G.; Trincaz-Duvoid, S.; Tripiana, M. F.; Trischuk, W.; Trka, Z.; Trocmé, B.; Troncon, C.; C-L Tseng, J.; Tsiafis, I.; Tsiareshka, P. V.; Tsipolitis, G.; Tskhadadze, E. G.; Tsukerman, I. I.; Tsulaia, V.; Tsuno, S.; Turala, M.; Turk Cakir, I.; Turlay, E.; Tuts, P. M.; Twomey, M. S.; Tyndel, M.; Typaldos, D.; Tyrvainen, H.; Tzamarioudaki, E.; Tzanakos, G.; Ueda, I.; Uhrmacher, M.; Ukegawa, F.; Ullán Comes, M.; Unal, G.; Underwood, D. G.; Undrus, A.; Unel, G.; Unno, Y.; Urkovsky, E.; Usai, G.; Usov, Y.; Vacavant, L.; Vacek, V.; Vachon, B.; Vahsen, S.; Valderanis, C.; Valenta, J.; Valente, P.; Valero, A.; Valkar, S.; Valls Ferrer, J. A.; Van der Bij, H.; van der Graaf, H.; van der Kraaij, E.; Van Eijk, B.; van Eldik, N.; van Gemmeren, P.; van Kesteren, Z.; van Vulpen, I.; Van Berg, R.; Vandelli, W.; Vandoni, G.; Vaniachine, A.; Vannucci, F.; Varanda, M.; Varela Rodriguez, F.; Vari, R.; Varnes, E. W.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vassilakopoulos, V. I.; Vassilieva, L.; Vataga, E.; Vaz, L.; Vazeille, F.; Vedrine, P.; Vegni, G.; Veillet, J. J.; Vellidis, C.; Veloso, F.; Veness, R.; Veneziano, S.; Ventura, A.; Ventura, S.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, J. C.; Vertogardov, L.; Vetterli, M. C.; Vichou, I.; Vickey, T.; Viehhauser, G. H. A.; Vigeolas, E.; Villa, M.; Villani, E. G.; Villate, J.; Villella, I.; Vilucchi, E.; Vincent, P.; Vincke, H.; Vincter, M. G.; Vinogradov, V. B.; Virchaux, M.; Viret, S.; Virzi, J.; Vitale, A.; Vivarelli, I.; Vives, R.; Vives Vaques, F.; Vlachos, S.; Vogt, H.; Vokac, P.; Vollmer, C. F.; Volpi, M.; Volpini, G.; von Boehn-Buchholz, R.; von der Schmitt, H.; von Toerne, E.; Vorobel, V.; Vorobiev, A. P.; Vorozhtsov, A. S.; Vorozhtsov, S. B.; Vos, M.; Voss, K. C.; Voss, R.; Vossebeld, J. H.; Vovenko, A. S.; Vranjes, N.; Vrba, V.; Vreeswijk, M.; Anh, T. Vu; Vuaridel, B.; Vudragovic, M.; Vuillemin, V.; Vuillermet, R.; Wänanen, A.; Wahlen, H.; Walbersloh, J.; Walker, R.; Walkowiak, W.; Wall, R.; Wallny, R. S.; Walsh, S.; Wang, C.; Wang, J. C.; Wappler, F.; Warburton, A.; Ward, C. P.; Warner, G. P.; Warren, M.; Warsinsky, M.; Wastie, R.; Watkins, P. M.; Watson, A. T.; Watts, G.; Waugh, A. T.; Waugh, B. M.; Weaverdyck, C.; Webel, M.; Weber, G.; Weber, J.; Weber, M.; Weber, P.; Weidberg, A. R.; Weilhammer, P. M.; Weingarten, J.; Weiser, C.; Wellenstein, H.; Wellisch, H. P.; Wells, P. S.; Wemans, A.; Wen, M.; Wenaus, T.; Wendler, S.; Wengler, T.; Wenig, S.; Wermes, N.; Werneke, P.; Werner, P.; Werthenbach, U.; Wheeler-Ellis, S. J.; Whitaker, S. P.; White, A.; White, M. J.; White, S.; Whittington, D.; Wicek, F.; Wicke, D.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wienemann, P.; Wiesmann, M.; Wiesmann, M.; Wijnen, T.; Wildauer, A.; Wilhelm, I.; Wilkens, H. G.; Williams, H. H.; Willis, W.; Willocq, S.; Wilmut, I.; Wilson, J. A.; Wilson, A.; Wingerter-Seez, I.; Winton, L.; Witzeling, W.; Wlodek, T.; Woehrling, E.; Wolter, M. W.; Wolters, H.; Wosiek, B.; Wotschack, J.; Woudstra, M. J.; Wright, C.; Wu, S. L.; Wu, X.; Wuestenfeld, J.; Wunstorf, R.; Xella-Hansen, S.; Xiang, A.; Xie, S.; Xie, Y.; Xu, G.; Xu, N.; Yamamoto, A.; Yamamoto, S.; Yamaoka, H.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, J. C.; Yang, S.; Yang, U. K.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yao, Y.; Yarradoddi, K.; Yasu, Y.; Ye, J.; Yilmaz, M.; Yoosoofmiya, R.; Yorita, K.; Yoshida, H.; Yoshida, R.; Young, C.; Youssef, S. P.; Yu, D.; Yu, J.; Yu, M.; Yu, X.; Yuan, J.; Yurkewicz, A.; Zaets, V. G.; Zaidan, R.; Zaitsev, A. M.; Zajac, J.; Zajacova, Z.; Zalite, A. Yu; Zalite, Yo K.; Zanello, L.; Zarzhitsky, P.; Zaytsev, A.; Zdrazil, M.; Zeitnitz, C.; Zeller, M.; Zema, P. F.; Zendler, C.; Zenin, A. V.; Zenis, T.; Zenonos, Z.; Zenz, S.; Zerwas, D.; Zhang, H.; Zhang, J.; Zheng, W.; Zhang, X.; Zhao, L.; Zhao, T.; Zhao, X.; Zhao, Z.; Zhelezko, A.; Zhemchugov, A.; Zheng, S.; Zhichao, L.; Zhou, B.; Zhou, N.; Zhou, S.; Zhou, Y.; Zhu, C. G.; Zhu, H. Z.; Zhuang, X. A.; Zhuravlov, V.; Zilka, B.; Zimin, N. I.; Zimmermann, S.; Ziolkowski, M.; Zitoun, R.; Zivkovic, L.; Zmouchko, V. V.; Zobernig, G.; Zoccoli, A.; Zoeller, M. M.; Zolnierowski, Y.; Zsenei, A.; zur Nedden, M.; Zychacek, V.

2008-08-01

The ATLAS detector as installed in its experimental cavern at point 1 at CERN is described in this paper. A brief overview of the expected performance of the detector when the Large Hadron Collider begins operation is also presented.

The kaon identification system in the NA62 experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romano, A.

2015-07-01

The main goal of the NA62 experiment at CERN is to measure the branching ratio of the ultra-rare K{sup +} → π{sup +} ν ν-bar decay with 10% accuracy. NA62 will use a 750 MHz high-energy un-separated charged hadron beam, with kaons corresponding to ∼6% of the beam, and a kaon decay-in-flight technique. The positive identification of kaons is performed with a differential Cherenkov detector (CEDAR), filled with Nitrogen gas and placed in the incoming beam. To stand the kaon rate (45 MHz average) and meet the performances required in NA62, the Cherenkov detector has been upgraded (KTAG) with newmore » photon detectors, readout, mechanics and cooling systems. The KTAG provides a fast identification of kaons with an efficiency of at least 95% and precise time information with a resolution below 100 ps. A half-equipped KTAG detector has been commissioned during a technical run at CERN in 2012, while the fully equipped detector, its readout and front-end have been commissioned during a pilot run at CERN in October 2014. The measured time resolution and efficiency are within the required performances. (authors)« less

[CERN-MEDICIS (Medical Isotopes Collected from ISOLDE): a new facility].

PubMed

Viertl, David; Buchegger, Franz; Prior, John O; Forni, Michel; Morel, Philippe; Ratib, Osman; Bühler Léo H; Stora, Thierry

2015-06-17

CERN-MEDICIS is a facility dedicated to research and development in life science and medical applications. The research platform was inaugurated in October 2014 and will produce an increasing range of innovative isotopes using the proton beam of ISOLDE for fundamental studies in cancer research, for new imaging and therapy protocols in cell and animal models and for preclinical trials, possibly extended to specific early phase clinical studies (phase 0) up to phase I trials. CERN, the University Hospital of Geneva (HUG), the University Hospital of Lausanne (CHUV), the Swiss Institute for Experimental Cancer (ISREC) at Swiss Federal Institutes of Technology (EPFL) that currently support the project will benefit of the initial production that will then be extended to other centers.

LHC@Home: a BOINC-based volunteer computing infrastructure for physics studies at CERN

NASA Astrophysics Data System (ADS)

Barranco, Javier; Cai, Yunhai; Cameron, David; Crouch, Matthew; Maria, Riccardo De; Field, Laurence; Giovannozzi, Massimo; Hermes, Pascal; Høimyr, Nils; Kaltchev, Dobrin; Karastathis, Nikos; Luzzi, Cinzia; Maclean, Ewen; McIntosh, Eric; Mereghetti, Alessio; Molson, James; Nosochkov, Yuri; Pieloni, Tatiana; Reid, Ivan D.; Rivkin, Lenny; Segal, Ben; Sjobak, Kyrre; Skands, Peter; Tambasco, Claudia; Veken, Frederik Van der; Zacharov, Igor

2017-12-01

The LHC@Home BOINC project has provided computing capacity for numerical simulations to researchers at CERN since 2004, and has since 2011 been expanded with a wider range of applications. The traditional CERN accelerator physics simulation code SixTrack enjoys continuing volunteers support, and thanks to virtualisation a number of applications from the LHC experiment collaborations and particle theory groups have joined the consolidated LHC@Home BOINC project. This paper addresses the challenges related to traditional and virtualized applications in the BOINC environment, and how volunteer computing has been integrated into the overall computing strategy of the laboratory through the consolidated LHC@Home service. Thanks to the computing power provided by volunteers joining LHC@Home, numerous accelerator beam physics studies have been carried out, yielding an improved understanding of charged particle dynamics in the CERN Large Hadron Collider (LHC) and its future upgrades. The main results are highlighted in this paper.

Partial nephrectomy for small children: Robot-assisted versus open surgery.

PubMed

Ballouhey, Quentin; Binet, Aurélien; Clermidi, Pauline; Braik, Karim; Villemagne, Thierry; Cros, Jérôme; Lardy, Hubert; Fourcade, Laurent

2017-12-01

To compare the outcomes of robot-assisted heminephrectomy for duplex kidney in children with those of open heminephrectomy. The present retrospective multicentric analysis reviewed the records of robot-assisted versus open heminephrectomy carried out for duplex kidney in children from 2007 to 2014. Demographic data, weight, surgical time, hospital stay, complications and outcome were recorded. Follow up was based on a clinical review, renal sonography and dimercaptosuccinic acid renal scintigraphy. A total of 15 patients underwent robot-assisted heminephrectomy, and 13 patients underwent retroperitoneal heminephrectomy by open approach. All patients weighed <15 kg. The mean age at the time of surgery was 20.2 months (range 7-39 months) in the robotic group, and 18.4 months (range 6-41 months) in the open group. The mean hospital stay was statistically longer for the open surgery group (6.3 days, range 5-8 days vs 3.4 days, range 1-7 days; P < 0.001). Regarding postoperative pain control, total morphine equivalent intake was statistically greater for the open group (0.52 mg/kg/day vs 1.08 mg/kg/day; P < 0.001). No patient lost the remaining healthy moiety. There was no significant difference in terms of operating time, complication rate or renal outcomes. Robot-assisted heminephrectomy in small children seems to offer comparable renal outcomes with those of its standard open surgery counterpart. Specific technical adjustments are necessary, which typically increase the set-up time. © 2017 The Japanese Urological Association.

CERN Computing in Commercial Clouds

NASA Astrophysics Data System (ADS)

Cordeiro, C.; Field, L.; Garrido Bear, B.; Giordano, D.; Jones, B.; Keeble, O.; Manzi, A.; Martelli, E.; McCance, G.; Moreno-García, D.; Traylen, S.

2017-10-01

By the end of 2016 more than 10 Million core-hours of computing resources have been delivered by several commercial cloud providers to the four LHC experiments to run their production workloads, from simulation to full chain processing. In this paper we describe the experience gained at CERN in procuring and exploiting commercial cloud resources for the computing needs of the LHC experiments. The mechanisms used for provisioning, monitoring, accounting, alarming and benchmarking will be discussed, as well as the involvement of the LHC collaborations in terms of managing the workflows of the experiments within a multicloud environment.

The keys to CERN conference rooms - Managing local collaboration facilities in large organisations

NASA Astrophysics Data System (ADS)

Baron, T.; Domaracky, M.; Duran, G.; Fernandes, J.; Ferreira, P.; Gonzalez Lopez, J. B.; Jouberjean, F.; Lavrut, L.; Tarocco, N.

2014-06-01

For a long time HEP has been ahead of the curve in its usage of remote collaboration tools, like videoconference and webcast, while the local CERN collaboration facilities were somewhat behind the expected quality standards for various reasons. This time is now over with the creation by the CERN IT department in 2012 of an integrated conference room service which provides guidance and installation services for new rooms (either equipped for videoconference or not), as well as maintenance and local support. Managing now nearly half of the 246 meeting rooms available on the CERN sites, this service has been built to cope with the management of all CERN rooms with limited human resources. This has been made possible by the intensive use of professional software to manage and monitor all the room equipment, maintenance and activity. This paper focuses on presenting these packages, either off-the-shelf commercial products (asset and maintenance management tool, remote audio-visual equipment monitoring systems, local automation devices, new generation touch screen interfaces for interacting with the room) when available or locally developed integration and operational layers (generic audio-visual control and monitoring framework) and how they help overcoming the challenges presented by such a service. The aim is to minimise local human interventions while preserving the highest service quality and placing the end user back in the centre of this collaboration platform.

Laparoscopic and open subtotal colectomies have similar short-term results.

PubMed

Hoogenboom, Froukje J; Bosker, Robbert J I; Groen, Henk; Meijerink, Wilhelmus J H J; Lamme, Bas; Pierie, Jean Pierre E N

2013-01-01

Laparoscopic subtotal colectomy (STC) is a complex procedure. It is possible that short-term benefits for segmental resections cannot be attributed to this complex procedure. This study aims to assess differences in short-term results for laparoscopic versus open STC during a 15-year single-institute experience. We reviewed consecutive patients undergoing laparoscopic or open elective or subacute STC from January 1997 to December 2012. Fifty-six laparoscopic and 50 open STCs were performed. The operation time was significantly longer in the laparoscopic group, median 266 min (range 121-420 min), compared to 153 min (range 90-408 min) in the open group (p < 0.001). Median hospital stay showed no statistical difference, 14 days (range 1-129 days) in the laparoscopic and 13 days (range 1-85 days) in the open group. Between-group postoperative complications were not statistically different. Laparoscopic STC has short-term results similar to the open procedure, except for a longer operation time. The laparoscopic approach for STC is therefore only advisable in selected patients combined with extensive preoperative counseling. Copyright © 2013 S. Karger AG, Basel.

The Integration of CloudStack and OCCI/OpenNebula with DIRAC

NASA Astrophysics Data System (ADS)

Méndez Muñoz, Víctor; Fernández Albor, Víctor; Graciani Diaz, Ricardo; Casajús Ramo, Adriàn; Fernández Pena, Tomás; Merino Arévalo, Gonzalo; José Saborido Silva, Juan

2012-12-01

The increasing availability of Cloud resources is arising as a realistic alternative to the Grid as a paradigm for enabling scientific communities to access large distributed computing resources. The DIRAC framework for distributed computing is an easy way to efficiently access to resources from both systems. This paper explains the integration of DIRAC with two open-source Cloud Managers: OpenNebula (taking advantage of the OCCI standard) and CloudStack. These are computing tools to manage the complexity and heterogeneity of distributed data center infrastructures, allowing to create virtual clusters on demand, including public, private and hybrid clouds. This approach has required to develop an extension to the previous DIRAC Virtual Machine engine, which was developed for Amazon EC2, allowing the connection with these new cloud managers. In the OpenNebula case, the development has been based on the CernVM Virtual Software Appliance with appropriate contextualization, while in the case of CloudStack, the infrastructure has been kept more general, which permits other Virtual Machine sources and operating systems being used. In both cases, CernVM File System has been used to facilitate software distribution to the computing nodes. With the resulting infrastructure, the cloud resources are transparent to the users through a friendly interface, like the DIRAC Web Portal. The main purpose of this integration is to get a system that can manage cloud and grid resources at the same time. This particular feature pushes DIRAC to a new conceptual denomination as interware, integrating different middleware. Users from different communities do not need to care about the installation of the standard software that is available at the nodes, nor the operating system of the host machine which is transparent to the user. This paper presents an analysis of the overhead of the virtual layer, doing some tests to compare the proposed approach with the existing Grid solution. License

Visits on 'lamb-viewing days' at a sheep farm open to the public was a risk factor for Q fever in 2009.

PubMed

Whelan, J; Schimmer, B; de Bruin, A; van Beest Holle, M Robert-du Ry; van der Hoek, W; ter Schegget, R

2012-05-01

Between February and May 2009, 347 laboratory-confirmed cases of acute Q fever were reported in a southern municipal health service region in The Netherlands. Commercial dairy-goat farms were implicated and control measures were initially targeted there. A preliminary investigation also implicated a non-dairy sheep farm, open to the public on 'lamb-viewing days'. This study tested the association between visiting the non-dairy sheep farm and developing Q fever in residents of the region between February and May 2009. A case-control study of 146 cases and 431 address-matched controls was conducted. Multivariable logistic regression analysis confirmed the association between visiting to the sheep farm and Q fever disease (matched odds ratio 43, 95% confidence interval 9-200). Other risk factors were being a smoker, having a past medical history and being aged >40 years. Vaccination of sheep and goats on farms open to the public should help to reduce the number of future human cases.

Cryogenic Control System Migration and Developments towards the UNICOS CERN Standard at INFN

NASA Astrophysics Data System (ADS)

Modanese, Paolo; Calore, Andrea; Contran, Tiziano; Friso, Alessandro; Pengo, Marco; Canella, Stefania; Burioli, Sergio; Gallese, Benedetto; Inglese, Vitaliano; Pezzetti, Marco; Pengo, Ruggero

The cryogenic control systems at Laboratori Nazionali di Legnaro (LNL) are undergoing an important and radical modernization, allowing all the plants controls and supervision systems to be renewed in a homogeneous way towards the CERN-UNICOS standard. Before the UNICOS migration project started there were as many as 7 different types of PLC and 7 different types of SCADA, each one requiring its own particular programming language. In these conditions, even a simple modification and/or integration on the program or on the supervision, required the intervention of a system integrator company, specialized in its specific control system. Furthermore it implied that the operators have to be trained to learn the different types of control systems. The CERN-UNICOS invented for LHC [1] has been chosen due to its reliability and planned to run and be maintained for decades on. The complete migration is part of an agreement between CERN and INFN.

CERN openlab: Engaging industry for innovation in the LHC Run 3-4 R&D programme

NASA Astrophysics Data System (ADS)

Girone, M.; Purcell, A.; Di Meglio, A.; Rademakers, F.; Gunne, K.; Pachou, M.; Pavlou, S.

2017-10-01

LHC Run3 and Run4 represent an unprecedented challenge for HEP computing in terms of both data volume and complexity. New approaches are needed for how data is collected and filtered, processed, moved, stored and analysed if these challenges are to be met with a realistic budget. To develop innovative techniques we are fostering relationships with industry leaders. CERN openlab is a unique resource for public-private partnership between CERN and leading Information Communication and Technology (ICT) companies. Its mission is to accelerate the development of cutting-edge solutions to be used by the worldwide HEP community. In 2015, CERN openlab started its phase V with a strong focus on tackling the upcoming LHC challenges. Several R&D programs are ongoing in the areas of data acquisition, networks and connectivity, data storage architectures, computing provisioning, computing platforms and code optimisation and data analytics. This paper gives an overview of the various innovative technologies that are currently being explored by CERN openlab V and discusses the long-term strategies that are pursued by the LHC communities with the help of industry in closing the technological gap in processing and storage needs expected in Run3 and Run4.

CAPE-OPEN WITH .NET TRAINING COURSE

EPA Science Inventory

On March 7, 2007 in Heidelberg, Germany, the CAPE-OPEN Laboratories Network (CO-LaN) is offering a one-day training seminar on implementing CAPE-OPEN compliant process modeling components (PMCs) using .NET-based development tools. This seminar will be geared to component develope...

Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle.

PubMed

Saowaphak, P; Duangjinda, M; Plaengkaeo, S; Suwannasing, R; Boonkum, W

2017-06-29

In this study, we estimated the genetic parameters and identified the putative quantitative trait loci (QTL) associated with the length of productive life (LPL), days open (DO), and 305-day milk yield for the first lactation (FM305) of crossbred Holstein dairy cattle. Data comprising 4,739 records collected between 1986 and 2004 were used to estimate the variance-covariance components using the multiple-trait animal linear mixed models based on the average information restricted maximum likelihood (AI-REML) algorithm. Thirty-six animals were genotyped using the Illumina BovineSNP50 Bead Chip [>50,000 single nucleotide polymorphisms (SNPs)] to identify the putative QTL in a genome-wide association study. The heritability of the production trait FM305 was 0.25 and that of the functional traits, LPL and DO, was low (0.10 and 0.06, respectively). The genetic correlation estimates demonstrated favorable negative correlations between LPL and DO (-0.02). However, we observed a favorable positive correlation between FM305 and LPL (0.43) and an unfavorable positive correlation between FM305 and DO (0.1). The GWAS results indicated that 23 QTLs on bovine chromosomes 1, 4, 5, 8, 15, 26, and X were associated with the traits of interest, and the putative QTL regions were identified within seven genes (SYT1, DOCK11, KLHL13, IL13RA1, PRKG1, GNA14, and LRRC4C). In conclusion, the heritability estimates of the LPL and DO were low. Therefore, the approach of multiple-trait selection indexes should be applied, and the QTL identified here should be considered for use in marker-assisted selection in the future.

Relative to open surgery, minimally-invasive renal and ureteral pediatric surgery offers no improvement in 30-day complications, yet requires longer operative time: Data from the National Surgical Quality Improvement Program Pediatrics.

PubMed

Colaco, Marc; Hester, Austin; Visser, William; Rasper, Alison; Terlecki, Ryan

2018-05-01

Performance of minimally-invasive surgery (MIS) is increasing relative to open surgery. We sought to compare the contemporary rates of short-term complications of open versus laparoscopic renal and ureteral surgery in pediatric patients. A retrospective cross-sectional analysis of the National Surgical Quality Improvement Program Pediatrics database was performed of all cases in 2014 identified using CPT procedure codes for nephrectomy, partial nephrectomy (PN), ureteroneocystostomy (UNC), and pyeloplasty, and reviewed for postoperative complications. Univariate analysis was performed to determine 30-day complications, with comparison between open and MIS approaches. Receiver operator curve (ROC) analysis was performed to determine differences in body surface area (BSA) and age for open versus MIS. Review identified 207 nephrectomies, 72 PN, 920 UNC, and 625 pyeloplasties. MIS was associated with older age and larger BSA except for cases of UNC. Apart from PN, operative durations were longer with MIS. However, only PN was associated with significantly longer length of hospital stay (LOS). There was no difference in incidence of all other 30-day complications. When evaluating BSA via ROC, the area under the curve (AUC) was found to be 0.730 and was significant. Children with a BSA greater than 0.408 m 2 were more likely to have MIS (sensitivity, 66.9%; specificity, 69.3%). Regarding age, the AUC was 0.732. Children older than 637.5 days were more likely to have MIS (sensitivity, 72.8%; specificity, 63.3%). Pediatric MIS is associated with longer operative time for nephrectomy, but shorter LOS following PN. Surgical approach was not associated with difference in short-term complications.

Preparation of a primary argon beam for the CERN fixed target physics.

PubMed

Küchler, D; O'Neil, M; Scrivens, R; Thomae, R

2014-02-01

The fixed target experiment NA61 in the North Area of the Super Proton Synchrotron is studying phase transitions in strongly interacting matter. Up to now they used the primary beams available from the CERN accelerator complex (protons and lead ions) or fragmented beams created from the primary lead ion beam. To explore a wider range of energies and densities a request was made to provide primary argon and xenon beams. This paper describes the results of the setting up and 10 week test run of the Ar(11+) beam from the 14.5 GHz ECR ion source and the linear accelerator (Linac3) at CERN.

User and group storage management the CMS CERN T2 centre

NASA Astrophysics Data System (ADS)

Cerminara, G.; Franzoni, G.; Pfeiffer, A.

2015-12-01

A wide range of detector commissioning, calibration and data analysis tasks is carried out by CMS using dedicated storage resources available at the CMS CERN Tier-2 centre. Relying on the functionalities of the EOS disk-only storage technology, the optimal exploitation of the CMS user/group resources has required the introduction of policies for data access management, data protection, cleanup campaigns based on access pattern, and long term tape archival. The resource management has been organised around the definition of working groups and the delegation to an identified responsible of each group composition. In this paper we illustrate the user/group storage management, and the development and operational experience at the CMS CERN Tier-2 centre in the 2012-2015 period.

Across Europe to CERN: Taking students on the ultimate physics experience

NASA Astrophysics Data System (ADS)

Wheeler, Sam

2018-05-01

In 2013, I was an Einstein Fellow with the U.S. Department of Energy and I was asked by a colleague, working in a senator's office, if I would join him in a meeting with a physicist to "translate" the science into something more understandable. That meeting turned out to be a wonderful opportunity I would never have otherwise had. During the meeting I met Michael Tuts, a physicist who was working on project ATLAS at CERN. Afterwards, I walked with him out of the Senate office building to Union Station and, in parting, he gave me his card and told me that if I were in Geneva that he could help me get a tour of CERN and the LHC.

50th Anniversary Open House

NASA Image and Video Library

2011-06-02

Astronaut Scott Altman talks with guests during a 50th Anniversary Open House activity at Stennis Space Center on June 2. Stennis' yearlong anniversary celebration culminates Oct. 25, the anniversary of the day in 1961 that NASA publicly announced plans to build the south Mississippi facility. The June 2 open house attracted more than 1,000 visitors.

Reproductive traits of Holsteins and Jerseys. Effects of age, milk yield, and clinical abnormalities on involution of cervix and uterus, ovulation, estrous cycles, detection of estrus, conception rate, and days open.

PubMed

Fonseca, F A; Britt, J H; McDaniel, B T; Wilk, J C; Rakes, A H

1983-05-01

Two hundred and twelve Holstein and Jersey cows were in a study to determine factors that affected reproductive traits. First ovulation occurred about 3 wk postpartum, and interval to first ovulation was greater in cows that had clinical abnormalities postpartum than in normal cows. Jerseys producing more milk ovulated sooner postpartum than lower producing herdmates. Involution of cervix and uterus occurred later postpartum in cows that had clinical problems postpartum. Involution of genital tract occurred later postpartum in older cows and sooner postpartum in cows that had higher milk yields. Duration of first postpartum estrous cycle was 4 days less than for second postpartum cycle. Percentages of estrous cycles detected by standing estrus were 43 and 73% for Holsteins and Jerseys. Estrous detection rates were highest for cows that produced slightly above the mean milk yield and did not differ between cows in highest and lowest milk production quartiles. First detected estrus and days to first insemination occurred later postpartum in Holsteins as milk yield deviation from herdmates increased, regardless of sign. In Jerseys, days to first insemination and days open increased linearly as milk yield increased. Days to first insemination and conception were greater in cows with postpartum clinical problems. Conception rate at first insemination postpartum increased in proportion to concentration of progesterone in blood samples collected during 12 days before first insemination. Overall, clinical problems at parturition and postpartum lowered reproductive performance in both breeds. There was a slight antagonism between milk yield and reproductive performance (days open) in Jerseys but not in Holsteins.

Exploring the day-to-day life of mothers dealing with preschool children who have behavioral disorders.

PubMed

Coke, Sallie; Spratling, Regena; Minick, Ptlene

2013-01-01

The purpose of this study was to explore the day-to-day life of mothers dealing with preschool children who have behavioral disorders and to explore the mothers' experiences with their children's health care. A qualitative design was used to explore mothers' experiences in their day-to-day lives. A purposive sample of eight mothers was interviewed in their homes. A recorded face-to-face format was used that included open-ended, semi-structured questions. Two major themes emerged from the day-to-day experiences of these mothers: "abandoning my other child" and "parenting in unsupportive environments". The theme of "parenting in unsupportive environments" reflects the frustrations the mothers felt in their day-to-day lives while trying to find help for their children. The theme of "abandoning my other child" refers to the siblings of the children with behavioral disorders being overlooked by the mothers because so much of the mothers' attention and time was given to the child with the behavioral disorder. Copyright © 2013 National Association of Pediatric Nurse Practitioners. Published by Mosby, Inc. All rights reserved.

PARTICLE PHYSICS: CERN Collider Glimpses Supersymmetry--Maybe.

PubMed

Seife, C

2000-07-14

Last week, particle physicists at the CERN laboratory in Switzerland announced that by smashing together matter and antimatter in four experiments, they detected an unexpected effect in the sprays of particles that ensued. The anomaly is subtle, and physicists caution that it might still be a statistical fluke. If confirmed, however, it could mark the long-sought discovery of a whole zoo of new particles--and the end of a long-standing model of particle physics.

Hatch opening

NASA Image and Video Library

2005-07-28

S114-E-5508 (28 July 2005) --- Astronaut Eileen M. Collins, STS-114 commander, prepares to open the hatch that will lead her and the entire Discovery crew into the International Space Station. This was just one highlight of a very busy day that earlier saw the flawless rendezvous and docking operations between the shuttle and the orbital outpost.

Measurements and FLUKA simulations of bismuth and aluminium activation at the CERN Shielding Benchmark Facility (CSBF)

NASA Astrophysics Data System (ADS)

Iliopoulou, E.; Bamidis, P.; Brugger, M.; Froeschl, R.; Infantino, A.; Kajimoto, T.; Nakao, N.; Roesler, S.; Sanami, T.; Siountas, A.

2018-03-01

The CERN High Energy AcceleRator Mixed field facility (CHARM) is located in the CERN Proton Synchrotron (PS) East Experimental Area. The facility receives a pulsed proton beam from the CERN PS with a beam momentum of 24 GeV/c with 5 ṡ1011 protons per pulse with a pulse length of 350 ms and with a maximum average beam intensity of 6.7 ṡ1010 p/s that then impacts on the CHARM target. The shielding of the CHARM facility also includes the CERN Shielding Benchmark Facility (CSBF) situated laterally above the target. This facility consists of 80 cm of cast iron and 360 cm of concrete with barite concrete in some places. Activation samples of bismuth and aluminium were placed in the CSBF and in the CHARM access corridor in July 2015. Monte Carlo simulations with the FLUKA code have been performed to estimate the specific production yields for these samples. The results estimated by FLUKA Monte Carlo simulations are compared to activation measurements of these samples. The comparison between FLUKA simulations and the measured values from γ-spectrometry gives an agreement better than a factor of 2.

Preparation of a primary argon beam for the CERN fixed target physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Küchler, D., E-mail: detlef.kuchler@cern.ch; O’Neil, M.; Scrivens, R.

2014-02-15

The fixed target experiment NA61 in the North Area of the Super Proton Synchrotron is studying phase transitions in strongly interacting matter. Up to now they used the primary beams available from the CERN accelerator complex (protons and lead ions) or fragmented beams created from the primary lead ion beam. To explore a wider range of energies and densities a request was made to provide primary argon and xenon beams. This paper describes the results of the setting up and 10 week test run of the Ar{sup 11+} beam from the 14.5 GHz ECR ion source and the linear acceleratormore » (Linac3) at CERN.« less

Air liquide 1.8 K refrigeration units for CERN LHC project

NASA Astrophysics Data System (ADS)

Hilbert, Benoît; Gistau-Baguer, Guy M.; Caillaud, Aurélie

2002-05-01

The Large Hadron Collider (LHC) will be CERN's next research instrument for high energy physics. This 27 km long circular accelerator will make intensive use of superconducting magnets, operated below 2.0 K. It will thus require high capacity refrigeration below 2.0 K [1, 2]. Coupled to a refrigerator providing 18 kW equivalent at 4.5 K [3], these systems will be able to absorb a cryogenic power of 2.4 kW at 1.8 K in nominal conditions. Air Liquide has designed one Cold Compressor System (CCS) pre-series for CERN-preceding 3 more of them (among 8 in total located around the machine). These systems, making use of cryogenic centrifugal compressors in a series arrangement coupled to room temperature screw compressors, are presented. Key components characteristics will be given.

Big Bang Day : Afternoon Play - Torchwood: Lost Souls

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2009-10-13

Martha Jones, ex-time traveller and now working as a doctor for a UN task force, has been called to CERN where they're about to activate the Large Hadron Collider. Once activated, the Collider will fire beams of protons together recreating conditions a billionth of a second after the Big Bang - and potentially allowing the human race a greater insight into what the Universe is made of. But so much could go wrong - it could open a gateway to a parallel dimension, or create a black hole - and now voices from the past are calling out to peoplemore » and scientists have started to disappear... Where have the missing scientists gone? What is the secret of the glowing man? What is lurking in the underground tunnel? And do the dead ever really stay dead? Lost Souls is a spin-off from the award-winning BBC Wales TV production Torchwood. It stars John Barrowman, Freema Agyeman, Eve Myles, Gareth David-Lloyd, Lucy Montgomery (of Titty Bang Bang) and Stephen Critchlow.« less

Big Bang Day : Afternoon Play - Torchwood: Lost Souls

ScienceCinema

None

2017-12-09

Martha Jones, ex-time traveller and now working as a doctor for a UN task force, has been called to CERN where they're about to activate the Large Hadron Collider. Once activated, the Collider will fire beams of protons together recreating conditions a billionth of a second after the Big Bang - and potentially allowing the human race a greater insight into what the Universe is made of. But so much could go wrong - it could open a gateway to a parallel dimension, or create a black hole - and now voices from the past are calling out to people and scientists have started to disappear... Where have the missing scientists gone? What is the secret of the glowing man? What is lurking in the underground tunnel? And do the dead ever really stay dead? Lost Souls is a spin-off from the award-winning BBC Wales TV production Torchwood. It stars John Barrowman, Freema Agyeman, Eve Myles, Gareth David-Lloyd, Lucy Montgomery (of Titty Bang Bang) and Stephen Critchlow.

Tour Opens Doors to Solar Homes

Science.gov Websites

, 1999 — The Tour of Solar Homes will open the doors of hundreds of passive and active solar homes available for $5 at NREL's Visitors Center on the day of the tour. The Visitors Center will open at 9 a.m solar electric systems, will be open 10 a.m. to 4 p.m. Ever wonder what it would feel like to live in a

Commissioning results of CERN HIE-ISOLDE and INFN ALPI cryogenic control systems

NASA Astrophysics Data System (ADS)

Inglese, V.; Pezzetti, M.; Calore, A.; Modanese, P.; Pengo, R.

2017-02-01

The cryogenic systems of both accelerators, namely HIE ISOLDE (High Intensity and Energy Isotope Separator On Line DEvice) at CERN and ALPI (Acceleratore Lineare Per Ioni) at LNL, have been refurbished. HIE ISOLDE is a major upgrade of the existing ISOLDE facilities, which required the construction of a superconducting linear accelerator consisting of six cryomodules, each containing five superconductive RF cavities and superconducting solenoids. The ALPI linear accelerator, similar to HIE ISOLDE, is located at Legnaro National Laboratories (LNL) and became operational in the early 90’s. It is composed of 74 superconducting RF cavities, assembled inside 22 cryostats. The new control systems are equipped with PLC, developed on the CERN UNICOS framework, which include Schneider and Siemens PLCs and various fieldbuses (Profibus DP and PA, WorldFIP). The control systems were developed in synergy between CERN and LNL in order to build, effectively and with an optimized use of resources, control systems allowing to enhance ease of operation, maintainability, and long-term availability. This paper describes (i) the cryogenic systems, with special focus on the design of the control systems hardware and software, (ii) the strategy adopted in order to achieve a synergic approach, and (iii) the commissioning results after the cool-down to 4.5 K of the cryomodules.

Big Bang Day: Engineering Solutions

ScienceCinema

None

2017-12-09

CERN's Large Hadron Collider is the most complicated scientific apparatus ever built. Many of the technologies it uses hadn't even been invented when scientists started building it. Adam Hart-Davis discovers what it takes to build the world's most intricate discovery machine.

QM2017: Status and Key open Questions in Ultra-Relativistic Heavy-Ion Physics

NASA Astrophysics Data System (ADS)

Schukraft, Jurgen

2017-11-01

Almost exactly 3 decades ago, in the fall of 1986, the era of experimental ultra-relativistic E / m ≫ 1) heavy ion physics started simultaneously at the SPS at CERN and the AGS at Brookhaven with first beams of light Oxygen ions at fixed target energies of 200 GeV/A and 14.6 GeV/A, respectively. The event was announced by CERN [CERN's subatomic particle accelerators: Set up world-record in energy and break new ground for physics (CERN-PR-86-11-EN) (1986) 4 p, issued on 29 September 1986. URL (http://cds.cern.ch/record/855571)

Contextualized Magnetism in Secondary School: Learning from the LHC (CERN)

ERIC Educational Resources Information Center

Cid, Ramon

2005-01-01

Physics teachers in secondary schools usually mention the world's largest particle physics laboratory--CERN (European Organization for Nuclear Research)--only because of the enormous size of the accelerators and detectors used there, the number of scientists involved in their activities and also the necessary international scientific…

Lectures from the European RTN Winter School on Strings, Supergravity and Gauge Theories, CERN, 16 20 January, 2006

NASA Astrophysics Data System (ADS)

Derendinger, J.-P.; Scrucca, C. A.; Uranga, A. M.

2006-11-01

This special issue is devoted to the proceedings of the conference 'Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland, from the 16 to the 20 of January 2006. This event was organized in the framework of the European Mobility Research and Training Network entitled 'Constituents, Fundamental Forces and Symmetries of the Universe'. It is part of a yearly series of scientific schools which have become a traditional rendezvous for young researchers of the community. The previous one was held at SISSA, in Trieste, Italy, in February 2005, and the next one will take place again at CERN, in January 2007. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of five general lectures of four hours each, whose notes are published in the present proceedings, and five working group discussion sessions, focused on specific topics of the network research program. It was attended by approximately 250 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress and to the open problems in string theory. String theory is expected to provide insights into the description of systems where the role of gravity is crucial. One prominent example of such systems are time-dependent backgrounds with big bang singularities, whose status in string theory is reviewed in the lecture notes by Ben Craps. In another main problem in quantum gravity, string theory gives a fascinating microscopic description of black holes and their properties. The lectures by Shiraz Minwalla review the thermal properties of black holes from their microscopic description in terms of a holographically dual large N field theory. Progress in the description of black hole microstates, and its interplay with the macroscopic description in terms of supergravity solutions via the

The 2017 Bioinformatics Open Source Conference (BOSC)

PubMed Central

Harris, Nomi L.; Cock, Peter J.A.; Chapman, Brad; Fields, Christopher J.; Hokamp, Karsten; Lapp, Hilmar; Munoz-Torres, Monica; Tzovaras, Bastian Greshake; Wiencko, Heather

2017-01-01

The Bioinformatics Open Source Conference (BOSC) is a meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. The 18th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2017) took place in Prague, Czech Republic in July 2017. The conference brought together nearly 250 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, open and reproducible science, and this year’s theme, open data. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community, called the OBF Codefest. PMID:29118973

The 2017 Bioinformatics Open Source Conference (BOSC).

PubMed

Harris, Nomi L; Cock, Peter J A; Chapman, Brad; Fields, Christopher J; Hokamp, Karsten; Lapp, Hilmar; Munoz-Torres, Monica; Tzovaras, Bastian Greshake; Wiencko, Heather

2017-01-01

The Bioinformatics Open Source Conference (BOSC) is a meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. The 18th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2017) took place in Prague, Czech Republic in July 2017. The conference brought together nearly 250 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, open and reproducible science, and this year's theme, open data. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community, called the OBF Codefest.

Grand opening extravanganza leads to partnership with NASA.

PubMed

Rees, T

1999-01-01

When Salinas Valley Memorial Healthcare System opened its expanded regional heart center it joined with NASA to present a 16-day grand opening that has turned into an ongoing relationship with the space agency.

N° 15-2000: ESA, CERN and ESO launch "Physics on Stage"

NASA Astrophysics Data System (ADS)

2000-03-01

European public. Why ESA, CERN, and ESO? As Europe's principal organisations in physics research (particle physics, space and astronomy), the three recognised their mutual responsibility to address the issue with the launch of a new initiative and the creative use of their own research to attract the attention of the general public and teachers alike. About the "European Science and Technology Week" The objective of the "European Science and Technology Week" is to improve the public's knowledge and understanding of science and technology - including the associated benefits for society as a whole. The week focuses on the European dimension of research, such as pan-European scientific and technological co-operation. The rationale for holding the Week has its roots in the importance of the role of science and technology in modern societies and the need therefore, to ensure that the public recognises its significance in our lives. The Week is a framework for special TV programmes, exhibitions, contests, conferences, electronic networking, and other science related activities to promote the public understanding of science and technology. The Week was launched in 1993, on the initiative of the European Commission. Raising public awareness of science and technology is now the subject of a clearly defined action within the Human Potential Programme of the Fifth Framework Programme. Notes [1] The same press release is published also by CERN and ESO. [2] The 22 countries are the member countries of at least one of the participating organisations or the European Union: Austria, Belgium, Bulgaria, the Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Luxembourg, the Netherlands, Norway, Poland, Portugal, the Slovak Republic, Spain, Sweden, Switzerland, United Kingdom. Statements by the Directors General of ESA, CERN, and ESO Antonio Rodotà (ESA): "Space has become an integral part of every day life. The immense technological development that has led

CERN's Common Unix and X Terminal Environment

NASA Astrophysics Data System (ADS)

Cass, Tony

The Desktop Infrastructure Group of CERN's Computing and Networks Division has developed a Common Unix and X Terminal Environment to ease the migration to Unix based Interactive Computing. The CUTE architecture relies on a distributed filesystem—currently Trans arc's AFS—to enable essentially interchangeable client work-stations to access both "home directory" and program files transparently. Additionally, we provide a suite of programs to configure workstations for CUTE and to ensure continued compatibility. This paper describes the different components and the development of the CUTE architecture.

Lectures from the European RTN Winter School on Strings, Supergravity and Gauge Fields, CERN, 15 19 January 2007

NASA Astrophysics Data System (ADS)

Derendinger, J.-P.; Scrucca, C. A.; Uranga, A.

2007-11-01

This special issue is devoted to the proceedings of the conference 'Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland, from the 15 to the 19 of January 2007. This event was organized in the framework of the European Mobility Research and Training Network entitled 'Constituents, Fundamental Forces and Symmetries of the Universe'. It is part of a yearly series of scientific schools, which represents what is by now a well established tradition. The previous conferences have been held at SISSA, in Trieste, Italy, in February 2005 and at CERN in January 2006. The next will again take place at CERN, in January 2008. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of several general lectures of four hours each, the notes of which are published in the present proceedings, and seven working group discussion sessions, focused on specific topics of the network research program. It was attended by approximatively 250 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress, and to the open problems, in string theory. String theory is a compelling candidate for a theory of all interactions. A basic challenge in this field is therefore to explore the connection of string theory models and the laws of physics in different realms, like high-energy particle physics, early cosmology, or physics of strongly coupled gauge theories. Concerning the exploration of string theory compactifications leading to realistic models of particle physics, one of the main obstacles in this direction is the proper understanding of supersymmetry breaking. The lecture notes by Nathan Seiberg review the realization of spontaneous breaking of supersymmetry in field theory, including recent developments via the use of meta-stable long-lived vacua. It is

Highlights from High Energy Neutrino Experiments at CERN

NASA Astrophysics Data System (ADS)

Schlatter, W.-D.

2015-07-01

Experiments with high energy neutrino beams at CERN provided early quantitative tests of the Standard Model. This article describes results from studies of the nucleon quark structure and of the weak current, together with the precise measurement of the weak mixing angle. These results have established a new quality for tests of the electroweak model. In addition, the measurements of the nucleon structure functions in deep inelastic neutrino scattering allowed first quantitative tests of QCD.

Gender in relation to work motivation, satisfaction and use of day center services among people with psychiatric disabilities.

PubMed

Eklund, Mona; Eklund, Lisa

2017-05-01

Day centres can prepare for open-market employment, and attendees' work motivation is key in this. Adopting a gender perspective, this study investigated (1) motivation for day centre attendance, satisfaction with the day centre services, number of hours spent there, and number and type of occupations performed; and (2) whether those factors were related with motivation for open-market employment. Women (n = 164) and men (n = 160) with psychiatric disabilities completed self-report questionnaires. There were no gender differences regarding satisfaction with the day centre services or number of hours spent there, but women engaged in more occupations. More women than men performed externally-oriented services and textile work, while men were in the majority in workshops. Externally oriented services, working in workshops, and low satisfaction with the day centre services were associated with higher motivation for employment. Women and men were equally motivated for employment. Women scored higher on motivation for attending the day centre, something that may deter transition into open-market employment. For men, less motivation for attending day centres may reduce their possibilities of gaining skills that can facilitate transitioning to open-market employment. Thus, the possibility for transitioning from day centre activities to open-market employment may be gendered.

The trigger system for K0→2 π0 decays of the NA48 experiment at CERN

NASA Astrophysics Data System (ADS)

Mikulec, I.

1998-02-01

A fully pipelined 40 MHz "dead-time-free" trigger system for neutral K0 decays for the NA48 experiment at CERN is described. The NA48 experiment studies CP-violation using the high intensity beam of the CERN SPS accelerator. The trigger system sums, digitises, filters and processes signals from 13 340 channels of the liquid krypton electro-magnetic calorimeter. In 1996 the calorimeter and part of the trigger electronics were installed and tested. In 1997 the system was completed and prepared to be used in the first NA48 physics data taking period. Cagliari, Cambridge, CERN, Dubna, Edinburgh, Ferrara, Firenze, Mainz, Orsay, Perugia, Pisa, Saclay, Siegen, Torino, Warszawa, Wien Collaboration.

Need and feasibility of telemedicine in non-urban day care centres.

PubMed

Setia, Monika; DelliFraine, Jami L

2010-01-01

There appear to have been no studies of telemedicine in rural day care centres. We have assessed the feasibility of using telemedicine in eight rural day care centres in Pennsylvania, from the day care centres' perspective. The average number of children in these centres was 76 (range 20-150). The centres sent an average of 4.7 children home each month because of illness. Using telephone and face-to-face interviews, we assessed their perceived need for and familiarity with telemedicine, as well as their openness and preparedness for implementing telemedicine. Most day care centres reported a need for telemedicine and were open to learning how to use it. Some centres were concerned about adequate space for the equipment, but overall, the centres felt that their resources were adequate. Telemedicine in rural day care centres appears to be feasible, and would have the potential to save time and money for parents, as well as perhaps improving health care for children in rural areas.

Techniques for hazard analysis and their use at CERN.

PubMed

Nuttall, C; Schönbacher, H

2001-01-01

CERN, The European Organisation for Nuclear Research is situated near Geneva and has its accelerators and experimental facilities astride the Swiss and French frontiers attracting physicists from all over the world to this unique laboratory. The main accelerator is situated in a 27 km underground ring and the experiments take place in huge underground caverns in order to detect the fragments resulting from the collision of subatomic particles at speeds approaching that of light. These detectors contain many hundreds of tons of flammable materials, mainly plastics in cables and structural components, flammable gases in the detectors themselves, and cryogenic fluids such as helium and argon. The experiments consume high amounts of electrical power, thus the dangers involved have necessitated the use of analytical techniques to identify the hazards and quantify the risks to personnel and the infrastructure. The techniques described in the paper have been developed in the process industries where they have been to be of great value. They have been successfully applied to CERN industrial and experimental installations and, in some cases, have been instrumental in changing the philosophy of the experimentalists and their detectors.

More "Hands-On" Particle Physics: Learning with ATLAS at CERN

ERIC Educational Resources Information Center

Long, Lynne

2011-01-01

This article introduces teachers and students to a new portal of resources called Learning with ATLAS at CERN (http://learningwithatlas-portal.eu/), which has been developed by a European consortium of academic researchers and schools' liaison and outreach providers from countries across Europe. It includes the use of some of the mind-boggling…

Open System for Earthquake Engineering Simulation - Home Page

Science.gov Websites

-X, an expert system for reliable pre-and post-processing of buildings is now available for free /post processor GiD. The interface is available though the the GID+OpenSees website OpenSees Days Europe

Using Open Space Technology for School Improvement.

ERIC Educational Resources Information Center

Cox, David

2002-01-01

Describes a theory referred to as Open Space Technology (OST), which holds that the most productive learning in conference settings takes place in the open space between formally scheduled conference sessions. Argues that OST can be applied to staff development days and other educational development programs. (Contains 10 references.) (NB)

Orthodontic treatment-induced temporal alteration of jaw-opening reflex excitability.

PubMed

Sasaki, Au; Hasegawa, Naoya; Adachi, Kazunori; Sakagami, Hiroshi; Suda, Naoto

2017-10-01

The impairment of orofacial motor function during orthodontic treatment needs to be addressed, because most orthodontic patients experience pain and motor excitability would be affected by pain. In the present study, the temporal alteration of the jaw-opening reflex excitability was investigated to determine if orthodontic treatment affects orofacial motor function. The excitability of jaw-opening reflex evoked by electrical stimulation on the gingiva and recorded bilaterally in the anterior digastric muscles was evaluated at 1 (D1), 3 (D3), and 7 days (D7) after orthodontic force application to the teeth of right side; morphological features (e.g., osteoclast genesis and tooth movement) were also evaluated. To clarify the underlying mechanism of orthodontic treatment-induced alteration of orofacial motor excitability, analgesics were administrated for 1 day. At D1 and D3, orthodontic treatment significantly decreased the threshold for inducing the jaw-opening reflex but significantly increased the threshold at D7. Other parameters of the jaw-opening reflex were also evaluated (e.g., latency, duration and area under the curve of anterior digastric muscles activity), and only the latency of the D1 group was significantly different from that of the other groups. Temporal alteration of the jaw-opening reflex excitability was significantly correlated with changes in morphological features. Aspirin (300 mg·kg -1 ·day -1 ) significantly increased the threshold for inducing the jaw-opening reflex, whereas a lower dose (75-150 mg·kg -1 ·day -1 ) of aspirin or acetaminophen (300 mg·kg -1 ·day -1 ) failed to alter the jaw-opening reflex excitability. These results suggest that an increase of the jaw-opening reflex excitability can be induced acutely by orthodontic treatment, possibly through the cyclooxygenase activation. NEW & NOTEWORTHY It is well known that motor function is affected by pain, but the effect of orthodontic treatment-related pain on the trigeminal

Massive and Open

ERIC Educational Resources Information Center

Fasimpaur, Karen

2013-01-01

MOOCs--massive open online courses--are all the rage these days, with hundreds of thousands of participants signing up and investors plunking down millions to get a piece of the pie. Why is there so much excitement about this new disruptive form of online learning, and how does this model apply to professional learning for teachers? Traditional…

TAKE OUR CHILDREN TO WORK DAY

NASA Image and Video Library

2016-06-23

NASA’S MARSHALL SPACE FLIGHT CENTER KICKS OFF ITS ANNUAL "TAKE OUR CHILDREN TO WORK DAY" EVENTS JUNE 23 WITH OPENING REMARKS FROM LOUCIOUS HIRES, DIRECTOR OF MARSHALL’S OFFICE OF DIVERSITY AND EQUAL OPPORTUNITY. AN ESTIMATED 500 POTENTIAL FUTURE SPACEFARERS, SCIENTISTS AND ENGINEERS IN GRADES 3-12 TOOK PART IN THE DAY’S ACTIVITIES, TOURS AND PRESENTATIONS.

EDITORIAL: Lectures from the European RTN Winter School on Strings, Supergravity and Gauge Theories, CERN, 21 25 January 2008

NASA Astrophysics Data System (ADS)

Derendinger, J.-P.; Orlando, D.; Uranga, A.

2008-11-01

This special issue is devoted to the proceedings of the conference 'RTN Winter School on Strings, Supergravity and Gauge Theories', which took place at CERN, the European Centre for Nuclear Research, in Geneva, Switzerland, on the 21 25 January 2008. This event was organized in the framework of the European Mobility Research and Training Network entitled 'Constituents, Fundamental Forces and Symmetries of the Universe'. It is part of a yearly series of scientific schools, which represents what is by now a well established tradition. The previous ones have been held at SISSA, in Trieste, Italy, in February 2005 and at CERN in January 2006. The next one will again take place at CERN, in February 2009. The school was primarily meant for young doctoral students and postdoctoral researchers working in the area of string theory. It consisted of several general lectures of four hours each, whose notes are published in the present proceedings, and five working group discussion sessions, focused on specific topics of the network research program. It was attended by approximatively 250 participants. The topics of the lectures were chosen to provide an introduction to some of the areas of recent progress, and to the open problems, in string theory. One of the most active areas in string theory in recent years is the AdS/CFT or gauge/gravity correspondence, which proposes the complete equivalence of string theory on (asymptotically) anti-de Sitter spacetimes with gauge theories. The duality relates the weak coupling regime of one system to the strongly coupled regime of the other, and is therefore very non-trivial to test beyond the supersymmetry-protected BPS sector. One of the key ideas to quantitatively match several quantities on both sides is the use of integrability, both in the gauge theory and the string side. The lecture notes by Nick Dorey provide a pedagogical introduction to the fascinating topic of integrability in AdS/CFT. On the string theory side, progress has

A scalable infrastructure for CMS data analysis based on OpenStack Cloud and Gluster file system

NASA Astrophysics Data System (ADS)

Toor, S.; Osmani, L.; Eerola, P.; Kraemer, O.; Lindén, T.; Tarkoma, S.; White, J.

2014-06-01

The challenge of providing a resilient and scalable computational and data management solution for massive scale research environments requires continuous exploration of new technologies and techniques. In this project the aim has been to design a scalable and resilient infrastructure for CERN HEP data analysis. The infrastructure is based on OpenStack components for structuring a private Cloud with the Gluster File System. We integrate the state-of-the-art Cloud technologies with the traditional Grid middleware infrastructure. Our test results show that the adopted approach provides a scalable and resilient solution for managing resources without compromising on performance and high availability.

Thermostructural characterization and structural elastic property optimization of novel high luminosity LHC collimation materials at CERN

NASA Astrophysics Data System (ADS)

Borg, M.; Bertarelli, A.; Carra, F.; Gradassi, P.; Guardia-Valenzuela, J.; Guinchard, M.; Izquierdo, G. Arnau; Mollicone, P.; Sacristan-de-Frutos, O.; Sammut, N.

2018-03-01

The CERN Large Hadron Collider is currently being upgraded to operate at a stored beam energy of 680 MJ through the High Luminosity upgrade. The LHC performance is dependent on the functionality of beam collimation systems, essential for safe beam cleaning and machine protection. A dedicated beam experiment at the CERN High Radiation to Materials facility is created under the HRMT-23 experimental campaign. This experiment investigates the behavior of three collimation jaws having novel composite absorbers made of copper diamond, molybdenum carbide graphite, and carbon fiber carbon, experiencing accidental scenarios involving the direct beam impact on the material. Material characterization is imperative for the design, execution, and analysis of such experiments. This paper presents new data and analysis of the thermostructural characteristics of some of the absorber materials commissioned within CERN facilities. In turn, characterized elastic properties are optimized through the development and implementation of a mixed numerical-experimental optimization technique.

HST at CERN an Amazing Adventure

NASA Astrophysics Data System (ADS)

Restivo, Evelyn

2009-04-01

The High School Teacher Program (HST) at the European Organization for Nuclear Research, CERN, in Geneva, Switzerland was initiated in 1998 by a group of scientists, as a multicultural international program designed to introduce high school physics teachers to high-energy physics. The goal of the program is to provide experiences and materials that will help teachers lead their students to a better understanding of the physical world. Interacting with physics teachers from around the world leads to new approaches for dealing with educational issues that all teachers encounter. The program includes a variety of tours, a series of lectures and classroom activities about the physics expected from the Large Hadron Collider.

CERN at 60: giant magnet journeys through Geneva

NASA Astrophysics Data System (ADS)

Banks, Michael

2014-07-01

More than 30,000 people descended onto Geneva's harbour last month to celebrate the bicentenary of the city's integration into Switzerland with a parade through the city. Joining the 1200 participants at the Genève200 celebrations were staff from the CERN particle-physics lab, which is located on the outskirts of Geneva, who paraded a superconducting dipole magnet - similar to the thousands used in the Large Hadron Collider - through the city's narrow streets on a 20 m lorry.

Open-book pelvic fractures with perineal open wounds: a significant morbid combination.

PubMed

Duchesne, Juan C; Bharmal, Husain M; Dini, Arash A; Islam, Tareq; Schmieg, Robert E; Simmons, Jon D; Wahl, Georgia M; Davis, John A; Krause, Peter; McSwain, Norman E

2009-12-01

Open-book pelvic fractures (OBPF) with concomitant intra-abdominal injuries carry a high morbidity and mortality; the significance of associated perineal open wound (OBPF-POW) has not been defined. We hypothesize that the presence of perineal open wounds increases morbidity, mortality, and concomitant use of hospital resources. Patients diagnosed with OBPF over a 5-year period at a Level I trauma center were identified by trauma registry review, and were retrospectively reviewed under an Institutional Review Board-approved protocol. Patients with OBPF without a perineal open wound were compared with those with OBPF-POW. Data collected included patient demographics, injury details, management, and outcomes. A total of 1,635 patients with blunt pelvic fractures were identified, of which 177 (10.8%) had OBPF. OBPF-POW (36/177) significantly increased the use of angioembolization, occurrence of sepsis, pelvic sepsis, ARDS, and multi-organ system failure. Patients with OBPF-POW had an increase of 13 days in length of hospitalization compared with the OBPF group (P < 0.001), with cost of $120,647.30 and $62,952.72 respectively (P < 0.001). Perineal open wounds complicate open-book pelvic fractures with significant increase in hospital resource utilization. Aggressive multidisciplinary evaluation and management is appropriate to detect and prevent complications.

DAMPE prototype and its beam test results at CERN

NASA Astrophysics Data System (ADS)

Wu, Jian; Hu, Yiming; Chang, Jin

The first Chinese high energy cosmic particle detector(DAMPE) aims to detect electron/gamma at the range between 5GeV and 10TeV in space. A prototype of this detector is made and tested using both cosmic muons and test beam at CERN. Energy and space resolution as well as strong separation power for electron and proton are shown in the results. The detector structure is illustrated as well.

New radiation protection calibration facility at CERN.

PubMed

Brugger, Markus; Carbonez, Pierre; Pozzi, Fabio; Silari, Marco; Vincke, Helmut

2014-10-01

The CERN radiation protection group has designed a new state-of-the-art calibration laboratory to replace the present facility, which is >20 y old. The new laboratory, presently under construction, will be equipped with neutron and gamma sources, as well as an X-ray generator and a beta irradiator. The present work describes the project to design the facility, including the facility placement criteria, the 'point-zero' measurements and the shielding study performed via FLUKA Monte Carlo simulations. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Hatch opening

NASA Image and Video Library

2005-07-28

S114-E-5509 (28 July 2005) --- Astronaut Eileen M. Collins, STS-114 commander, has just opened the hatch that will lead her and the entire Discovery crew into the International Space Station. Astronaut Andrew S.W. Thomas, mission specialist, is partially visible at left edge of frame. This was just one highlight of a very busy day that earlier saw the flawless rendezvous and docking operations between the shuttle and the orbital outpost.

25th Birthday Cern- Restaurant

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2006-05-05

Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

[The CERN and the megascience].

PubMed

Aguilar Peris, José

2006-01-01

In this work we analyse the biggest particle accelerator in the world: the LHC (Large Hadron Collider). The ring shaped tunnel is 27 km long and it is buried over 110 meters underground, straddling the border betwen France and Switzerland at the CERN laboratory near Geneva. Its mission is to recreate the conditions that existed shortly after the Big-Bang and to look for the hypothesised Higgs particle. The LHC will accelerate protons near the speed of the light and collide them head on at an energy of to 14 TeV (1 TeV = 10(12) eV). Keeping such high energy in the proton beams requires enormous magnetic fields which are generated by superconducting electromagnets chilled to less than two degrees above absolute zero. It is expected that LHC will be inaugurated in summer 2007.

Terror in the Board Room: The Bid-Opening Process

ERIC Educational Resources Information Center

Shoop, James

2009-01-01

Competitive bids and the bid-opening process are the cornerstones of public school purchasing. The bid-opening process does not begin on the day of the bid opening. It begins with good planning by the purchasing agent to ensure that the advertised bid complies with the public school contracts law. In New Jersey, that raises the following…

Track reconstruction in the inhomogeneous magnetic field for Vertex Detector of NA61/SHINE experiment at CERN SPS

NASA Astrophysics Data System (ADS)

Merzlaya, Anastasia; NA61/SHINE Collaboration

2017-01-01

The heavy-ion programme of the NA61/SHINE experiment at CERN SPS is expanding to allow precise measurements of exotic particles with lifetime few hundred microns. A Vertex Detector for open charm measurements at the SPS is being constructed by the NA61/SHINE Collaboration to meet the challenges of high spatial resolution of secondary vertices and efficiency of track registration. This task is solved by the application of the coordinate sensitive CMOS Monolithic Active Pixel Sensors with extremely low material budget in the new Vertex Detector. A small-acceptance version of the Vertex Detector is being tested this year, later it will be expanded to a large-acceptance version. Simulation studies will be presented. A method of track reconstruction in the inhomogeneous magnetic field for the Vertex Detector was developed and implemented. Numerical calculations show the possibility of high precision measurements in heavy ion collisions of strange and multi strange particles, as well as heavy flavours, like charmed particles.

FwWebViewPlus: integration of web technologies into WinCC OA based Human-Machine Interfaces at CERN

NASA Astrophysics Data System (ADS)

Golonka, Piotr; Fabian, Wojciech; Gonzalez-Berges, Manuel; Jasiun, Piotr; Varela-Rodriguez, Fernando

2014-06-01

The rapid growth in popularity of web applications gives rise to a plethora of reusable graphical components, such as Google Chart Tools and JQuery Sparklines, implemented in JavaScript and run inside a web browser. In the paper we describe the tool that allows for seamless integration of web-based widgets into WinCC Open Architecture, the SCADA system used commonly at CERN to build complex Human-Machine Interfaces. Reuse of widely available widget libraries and pushing the development efforts to a higher abstraction layer based on a scripting language allow for significant reduction in maintenance of the code in multi-platform environments compared to those currently used in C++ visualization plugins. Adequately designed interfaces allow for rapid integration of new web widgets into WinCC OA. At the same time, the mechanisms familiar to HMI developers are preserved, making the use of new widgets "native". Perspectives for further integration between the realms of WinCC OA and Web development are also discussed.

Dorothy Day: A Love of Fiction and Her Love of the Poor

ERIC Educational Resources Information Center

Brady, Judith Ann

2010-01-01

Dorothy Day's love of the poor originated from reading novels that portrayed the poor as persons worthy of respect. This article explores how Day's reading novels opened her mind and heart to the realities of poverty. The methodology is literature-based. Dorothy Day's autobiography reveals the novelists who captivated her mind and cultivated a…

Deployment and Operational Experiences with CernVM-FS at the GridKa Tier-1 Center

NASA Astrophysics Data System (ADS)

Alef, Manfred; Jäger, Axel; Petzold and, Andreas; Verstege, Bernhard

2012-12-01

In 2012 the GridKa Tier-1 computing center hosts 130 kHS06 computing resources and 14PB disk and 17PB tape space. These resources are shared between the four LHC VOs and a number of national and international VOs from high energy physics and other sciences. CernVM-FS has been deployed at GridKa to supplement the existing NFS-based system to access VO software on the worker nodes. It provides a solution tailored to the requirement of the LHC VOs. We will focus on the first operational experiences and the monitoring of CernVM-FS on the worker nodes and the squid caches.

Alcohol-related fan behavior on college football game day.

PubMed

Glassman, Tavis; Werch, Chudley E; Jobli, Edessa; Bian, Hui

2007-01-01

High-risk drinking on game day represents a unique public health challenge. The authors examined the drinking behavior of college football fans and assessed the support for related interventions. The authors randomly selected 762 football fans, including college students, alumni, and other college football fans, to complete an anonymous online game-day survey. The authors collected data on participants' drinking behaviors and support for specific game-day interventions. Analysis revealed that, overall, fans drank significantly more on game day than they did the last time they partied or socialized. Nondrinkers were the most supportive of game-day interventions, followed by moderate drinkers, whereas heavy drinkers offered the least support. With the exception of limiting tailgating hours on game day, fans support game-day interventions, including alcohol-free alternatives, designating tailgating areas where open containers are permitted, and increasing law enforcement efforts.

Open versus laparoscopic Roux-en-Y gastric bypass: a comparative study of over 25,000 open cases and the major laparoscopic bariatric reported series.

PubMed

Jones, Kenneth B; Afram, Joseph D; Benotti, Peter N; Capella, Rafael F; Cooper, C Gary; Flanagan, Latham; Hendrick, Steven; Howell, L Michael; Jaroch, Mark T; Kole, Kerry; Lirio, Oscar C; Sapala, James A; Schuhknecht, Michael P; Shapiro, Robert P; Sweet, William A; Wood, Michael H

2006-06-01

Laparoscopic bariatric surgery has experienced a rapid expansion of interest over the past 5 years, with a 470% increase. This rapid expansion has markedly increased overall cost, reducing surgical access. Many surgeons believe that the traditional open approach is a cheaper, safer, equally effective alternative. 16 highly experienced "open" bariatric surgeons with a combined total of 25,759 cases representing >200 surgeon years of experience, pooled their open Roux-en-Y gastric bypass (ORYGBP) data, and compared their results to the leading laparoscopic (LRYGBP) papers in the literature. In the overall series, the incisional hernia rate was 6.4% using the standard midline incision. Utilizing the left subcostal incision (LSI), it was only 0.3%. Return to surgery in <30 days was 0.7%, deaths 0.25%, and leaks 0.4%. Average length of stay was 3.4 days, and return to usual activity 21 days. Small bowel obstruction was significantly higher with the LRYGBP. Surgical equipment costs averaged approximately $3,000 less for "open" cases. LRYGBP had an added expense for longer operative time. This more than made up for the shorter length of stay with the laparoscopic approach. The higher cost, higher leak rate, higher rate of small bowel obstruction, and similar long-term weight loss results make the "open" RYGBP our preferred operation. If the incision is taken out of the equation (i.e. use of the LSI), the significant advantages of the open technique become even more obvious.

34 CFR 300.11 - Day; business day; school day.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Day; business day; school day. 300.11 Section 300.11... CHILDREN WITH DISABILITIES General Definitions Used in This Part § 300.11 Day; business day; school day. (a) Day means calendar day unless otherwise indicated as business day or school day. (b) Business day...

STS-101: Crew Activity Report / Flight Day 5

NASA Technical Reports Server (NTRS)

2000-01-01

The primary mission objective for STS-101 was to deliver supplies to the International Space Station, perform a space walk, and reboost the station from 230 statute miles to 250 statute miles. The commander of this mission was, James D. Haslsell. The crew was Scott J. Horowitz, the pilot, and mission specialists Mary Ellen Weber, Jeffrey N. Williams, James S. Voss, Susan J. Helms, and Yuri Vladimirovich Usachev. This videotape shows the activities of the fifth day of the mission. The day's activities started with the opening of the hatch to the space station. Helms and Usachev then opened the hatch to the station's Unity Connecting Module. The crew also placed ducting throughout the Zarya Control Module to improve air circulation and prevent problems with stale air. Helms and Usachev are shown replacing two of six batteries to be replaced in this mission in the Zarya module. The crew began moving supplies into the space station. There are several shots of the interior of the space station.

Lead Ions and Coulomb's Law at the LHC (CERN)

ERIC Educational Resources Information Center

Cid-Vidal, Xabier; Cid, Ramon

2018-01-01

Although for most of the time the Large Hadron Collider (LHC) at CERN collides protons, for around one month every year lead ions are collided, to expand the diversity of the LHC research programme. Furthermore, in an effort not originally foreseen, proton-lead collisions are also taking place, with results of high interest to the physics…

The Proton Synchrotron (PS): At the Core of the CERN Accelerators

NASA Astrophysics Data System (ADS)

Cundy, Donald; Gilardoni, Simone

The following sections are included: * Introduction * Extraction: Getting the Beam to Leave the Accelerator * Acceleration and Bunch Gymnastics * Boosting PS Beam Intensity * Capacitive Energy Storage Replaces Flywheel * Taking the Neutrinos by the Horns * OMEGA: Towards the Electronic Bubble Chamber * ISOLDE: Targeting a New Era in Nuclear Physics * The CERN n_TOF Facility: Catching Neutrons on the Fly * References

Children using Day Nurseries' Facilities can be Associated with more Risk to Nonnutritive Sucking Habits.

PubMed

Alves, Fabiana Bt; Wambier, Denise S; Alvarez, Jenny Ha; da Rocha, José Cf; Kummer, Thais R; de Castro, Vanessa C; Cabral, Howard; Kozlowski, Vitoldo A

2016-09-01

This study evaluated the expression of nonnutritive sucking habits and the presence of malocclusion in children using day nurseries' facilities. The 195 children (7-40 months) attending 18 public day nurseries were evaluated clinically in Ponta Grossa, Brazil. Statistical package software was used for descriptive, univariate, bivariate, and multiple logistic regressions of the data about the socioeconomic condition, educational family status, malocclusions, and prevalence of nonnutritive sucking habits among the children. The pacifier users had a statistically significant, explanatory association with open bite [odds ratio (OR) = 10.97; 95% confidence interval (CI): 4.95, 24.31; p < 0.0001]. The children older than 25 months had more open bite than younger children (OR = 6.07; 95% CI: 2.81, 13.11; p < 0.0001). Of the children examined, 35.4% had an anterior open bite, 0.51% had posterior cross-bite, and 1.03% showed finger-sucking habits. A high frequency of pacifier-sucking habits was found (52%), with a significant association between this habit and anterior open bite (p < 0.0001, OR = 7.49; 95% CI: 3.71, 15.15). The 126 children without open bite (36.5%) were pacifier users. There was suggestive, though nonsignificant, evidence of a difference in pacifier use by gender (males, 34%; females, 46%; p = 0.07). The 69 children with open bite (81.16%) were pacifier users and (18.84%) nonusers. The boys showed a slightly greater association with open bite (OR = 21.33; 95% CI: 6.12, 74.40; p < 0.0001) than girls (OR = 5.03; 95% CI: 1.26, 20.00; p = 0.02) in the age group of 25 to 40 months; however, it was not observed in younger children. Pacifier use is a predictor for open bite in children from the lower socioeconomic classes using day nurseries' facilities. The parents, guardians, and caregivers working in public day nurseries should be advised to monitor nonnutritive sucking habits in order to avoid or minimize the occurrence of malocclusion. It demonstrates that

STS-89 Day 03 Highlights

NASA Technical Reports Server (NTRS)

1998-01-01

On this third day of the STS-89 mission, the flight crew, Cmdr. Terrence W. Wilcutt, Pilot Frank Edwards, and Mission Specialists Michael P. Anderson, James F. Reilly, Bonnie J. Dunbar, Salizhan Shakirovich Sharipov, David A. Wolf and Andrew S.W. Thomas, can be seen performing a flawless docking with the Mir. The linkup occurred while the two spaceships flew over southeastern Russia, west of Kazakhstan. After the docking the two crews open the entry hatch and greet each other.

Evaluation of Biomarkers of Exposure in Smokers Switching to a Carbon-Heated Tobacco Product: A Controlled, Randomized, Open-Label 5-Day Exposure Study

PubMed Central

Haziza, Christelle; Weitkunat, Rolf; Magnette, John

2016-01-01

Introduction: Tobacco harm reduction aims to provide reduced risk alternatives to adult smokers who would otherwise continue smoking combustible cigarettes (CCs). This randomized, open-label, three-arm, parallel-group, single-center, short-term confinement study aimed to investigate the effects of exposure to selected harmful and potentially harmful constituents (HPHCs) of cigarette smoke in adult smokers who switched to a carbon-heated tobacco product (CHTP) compared with adult smokers who continued to smoke CCs and those who abstained from smoking for 5 days. Methods: Biomarkers of exposure to HPHCs, including nicotine and urinary excretion of mutagenic material, were measured in 24-hour urine and blood samples in 112 male and female Caucasian smokers switching from CCs to the CHTP ad libitum use. Puffing topography was assessed during product use. Results: Switching to the CHTP or smoking abstinence (SA) resulted in marked decreases from baseline to Day 5 in all biomarkers of exposure measured, including carboxyhemoglobin (43% and 55% decrease in the CHTP and SA groups, respectively). The urinary excretion of mutagenic material was also markedly decreased on Day 5 compared with baseline (89% and 87% decrease in the CHTP and SA groups, respectively). No changes in biomarkers of exposure to HPHCs or urinary mutagenic material were observed between baseline and Day 5 in the CC group. Conclusions: Our results provide clear evidence supporting a reduction in the level of exposure to HPHCs of tobacco smoke in smokers who switch to CHTP under controlled conditions, similar to that observed in SA. Implications: The reductions observed in biomarkers of exposure to HPHCs of tobacco smoke in this short-term study could potentially also reduce the incidence of cancer, cardiovascular and respiratory diseases in those smokers who switch to a heated tobacco product. PMID:26817490

25th Birthday Cern- Restaurant

ScienceCinema

None

2017-12-09

Cérémonie du 25ème anniversaire du Cern avec plusieurs orateurs et la présence de nombreux autorités cantonales et communales genevoises et personnalités, directeurs généraux, ministres, chercheurs.... Le conseiller féderal et chef du département des affaires étrangères de la confédération Monsieur Pierre Aubert prend la parole pour célébrer à la fois les résultats très remarquables de la coopération internationale en matière scientifique, mais aussi la volonté politique des états européens de mettre en commun leurs ressources pour faire oeuvre d'avenir. Un grand hommage est aussi donné aux deux directeurs disparus, les prof.Bakker et Gregory.

The SHIP facility at CERN

NASA Astrophysics Data System (ADS)

De Lellis, Giovanni

2016-04-01

Searches for new physics with accelerators are being performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experimental facility meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored from the experimental point of view. A beam dump facility, built at CERN in the north area, using 400 GeV protons is a copious factory of charmed hadrons and could be used to probe the existence of such particles. The beam dump is also an ideal source of tau neutrinos, the less known particle in the Standard Model. In particular, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment and outline the performances of a detector operating at the same facility for the search for the τ → μμμ decay.

Do Street Robbery Location Choices Vary Over Time of Day or Day of Week? A Test in Chicago

PubMed Central

Ruiter, Stijn; Block, Richard

2016-01-01

Objectives: This article examines the hypothesis that in street robbery location choices, the importance of location attributes is conditional on the time of day and on the day of the week. Method: The hypothesis is assessed by estimating and comparing separate discrete location choice models for each two-hour time block of the day and for each day of the week. The spatial units of analysis are census blocks. Their relevant attributes include presence of various legal and illegal cash economies, presence of high schools, measures of accessibility, and distance from the offender’s home. Results: The hypothesis is strongly rejected because for almost all census block attributes, their importance hardly depends on time of day or day of week. Only the effect of high schools in census blocks follows expectations, as its effect is only demonstrated at the times and on the days that schools are open. Conclusions: The results suggest that street robbers’ location choices are not as strongly driven by spatial variations in immediate opportunities as has been suggested in previous studies. Rather, street robbers seem to perpetrate in the environs of cash economies and transit hubs most of the time irrespective of how many potential victims are around. PMID:28232756

STS-79 Flight Day 9

NASA Technical Reports Server (NTRS)

1996-01-01

On this ninth day of the STS-79 mission, the flight crew, Cmdr. William F. Readdy, Pilot Terrence W. Wilcutt, Mission Specialists, Thomas D. Akers, Shannon Lucid, Jay Apt, and Carl E. Walz having completed five days of joint operations between the American astronauts and the Russian cosmonauts are seen flying solo once again after undocking from the Mir Space Station. As Atlantis/Mir flew over the Ural Mountains of central Asia, the docking hooks and latches that joined the vehicles together were commanded open and Atlantis drifted slowly away from Mir. Wilcutt then initiated a tail-forward fly-around of the Russian space station. After one and one-half revolutions around Mir, Atlantis' jets were fired in a separation maneuver to enable Atlantis to break away from Mir. On board Atlantis, the six-member crew is settling back into its normal routine with a fairly light schedule for the remainder of the day. Early in the morning as Atlantis flew over the United States, the crew took time to talk with anchors for the CBS Up to the Minute' network news broadcast.

Open heart surgery after renal transplantation.

PubMed

Yamamura, Mitsuhiro; Miyamoto, Yuji; Mitsuno, Masataka; Tanaka, Hiroe; Ryomoto, Masaaki; Fukui, Shinya; Tsujiya, Noriko; Kajiyama, Tetsuya; Nojima, Michio

2014-09-01

to evaluate the strategy for open heart surgery after renal transplantation performed in a single institution in Japan. we reviewed 6 open heart surgeries after renal transplantation in 5 patients, performed between January 1992 and December 2012. The patients were 3 men and 2 women with a mean age of 60 ± 11 years (range 46-68 years). They had old myocardial infarction and unstable angina, aortic and mitral stenosis, left arterial myxoma, aortic stenosis, and native valve endocarditis followed by prosthetic valve endocarditis. Operative procedures included coronary artery bypass grafting, double-valve replacement, resection of left arterial myxoma, 2 aortic valve replacements, and a double-valve replacement. Renal protection consisted of steroid cover (hydrocortisone 100-500 mg or methylprednisolone 1000 mg) and intravenous immunosuppressant infusion (cyclosporine 30-40 mg day(-1) or tacrolimus 1.0 mg day(-1)). 5 cases were uneventful and good renal graft function was maintained at discharge (serum creatinine 2.1 ± 0.5 mg dL(-1)). There was one operative death after emergency double-valve replacement for methicillin-resistant Staphylococcus aureus-associated prosthetic valve endocarditis. Although the endocarditis improved after valve replacement, the patient died of postoperative pneumonia on postoperative day 45. careful perioperative management can allow successful open heart surgery after renal transplantation. However, severe complications, especially methicillin-resistant Staphylococcus aureus infection, may cause renal graft loss. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Comparison of Open and Closed Hand Fractures and the Effect of Urgent Operative Intervention.

PubMed

Minhas, Shobhit V; Catalano, Louis W

2018-06-13

To establish and compare the incidence of 30-day postoperative infection in surgically managed open and closed metacarpal and phalangeal fractures, and to determine whether open fractures treated urgently had a lower incidence of postoperative infection. We conducted a retrospective analysis of patient demographics, comorbidities, and 30-day infection rates of patients undergoing operative fixation of metacarpal, proximal, or middle phalanx fractures from 2008 to 2015 using the American College of Surgeons' National Surgical Quality Improvement Program database. A total of 3,506 patients were identified and patient variables and infection incidence were compared between open and closed injuries, as well as open injuries managed within 1 day of admission and those treated on an elective basis or treated more than 1 day after admission. Bivariate analysis was used to determine independent risk factors for postoperative infection. Although 34.2% of open hand fractures were taken urgently to the operating room, the diagnosis of open fractures along with nonurgent surgical treatment for open fractures was associated with a low incidence of postoperative infection. In addition, smoking was a risk factor for postoperative infection although anatomic location (phalanx vs metacarpal) was not. Patients undergoing surgery for metacarpal or proximal/middle phalangeal fractures are not at greater risk for infection based on the diagnosis of open fracture alone. In addition, patients with open fractures who are taken to the operating room more than 1 day from presentation did not have a higher incidence of infection. Smoking is associated with increased 30-day infection rates after surgery, and surgeons should identify these patients for preoperative risk stratification, counseling, and postoperative wound monitoring. Prognostic II. Copyright © 2018 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

Outcomes of infants undergoing robot-assisted laparoscopic pyeloplasty compared to open repair.

PubMed

Dangle, Pankaj P; Kearns, James; Anderson, Blake; Gundeti, Mohan S

2013-12-01

Robotic surgery has evolved from simple extirpative surgery to complex reconstructions even in infants. Data are lacking comparing surgical and direct costs to open approaches. We describe the feasibility, salient tips and outcomes of robot-assisted laparoscopic pyeloplasty compared to an open approach. We evaluated patients undergoing open pyeloplasty or robot-assisted laparoscopic pyeloplasty. Ten patients in each group met inclusion criteria. Mean patient age was 3.31 months in the open group and 7.3 months in the robotic group (p=0.02). Postoperative outcomes including length of stay (2.2 vs 2.1 days), estimated blood loss (6.5 vs 7.6 ml), days to regular diet (1 vs 1.1) and days to Foley catheter removal (1.3 vs 1.3) were similar between the open and robotic groups. Total operating time (199 vs 242 minutes) was significantly longer in the robotic group. Postoperative improvement in hydronephrosis was identical in both groups. Direct costs, excluding amortization, robotic cost, maintenance and depreciation, were $4,410 in the open group and $4,979 in the robotic group (p=0.10). In our preliminary experience robotic pyeloplasty in infants is feasible and safe. The immediate outcomes are similar to those of an open approach. The robotic technique in infants currently has the benefits of improved esthetic appearance, improved pain control and similar direct costs compared to the traditional open approach. Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Simultaneous repair of bilateral groin hernias: open or laparoscopic approach?

PubMed

Krähenbühl, L; Schäfer, M; Schilling, M; Kuzinkovas, V; Büchler, M W

1998-08-01

A persistent problem in hernia surgery concerns the repair of bilateral inguinal hernias. A retrospective analysis of 78 patients with bilateral inguinal hernias was performed. Hernia repair was performed either by an open anterior access (modified Shouldice repair) or a laparoscopic posterior approach (TAPP repair). The two patient groups were similar with regard to ASA classification, age, and sex. The intraoperative complication rate was low (2.6% to 7.8%), whereas postoperative complications occurred more frequently (7.7% to 15.4%). The recurrence rate was low in both groups: 5.1% for the open group and 1.3% for the laparoscopic group. The mean hospital stay was 4 days for both groups, and the mean off-work times were 56.4 days and 17.9 days for the open and laparoscopic group, respectively (p < 0.05). Both procedures gave satisfactory results. The main advantages of the laparoscopic approach are the shorter convalescence time and quicker return to work.

Open lung ventilation improves functional residual capacity after extubation in cardiac surgery.

PubMed

Reis Miranda, Dinis; Struijs, Ard; Koetsier, Peter; van Thiel, Robert; Schepp, Ronald; Hop, Wim; Klein, Jan; Lachmann, Burkhard; Bogers, Ad J J C; Gommers, Diederik

2005-10-01

After cardiac surgery, functional residual capacity (FRC) after extubation is reduced significantly. We hypothesized that ventilation according to the open lung concept (OLC) attenuates FRC reduction after extubation. A prospective, single-center, randomized, controlled clinical study. Cardiothoracic operating room and intensive care unit of a university hospital. Sixty-nine patients scheduled for elective coronary artery bypass graft and/or valve surgery with cardiopulmonary bypass. Before surgery, patients were randomly assigned to three groups: (1) conventional ventilation (CV); (2) OLC, started after arrival in the intensive care unit (late open lung); and (3) OLC, started directly after intubation (early open lung). In both OLC groups, recruitment maneuvers were applied until Pao2/Fio2 was >375 Torr (50 kPa). No recruitment maneuvers were applied in the CV group. FRC was measured preoperatively and 1, 3, and 5 days after extubation. Peripheral hemoglobin saturation (Spo2) was measured daily till the third day after extubation while the patient was breathing room air. Hypoxemia was defined by an Spo2 value < or =90%. Averaged over the 5 postoperative days, FRC was significantly higher in the early open lung group and tended to be higher in the late open lung group, in comparison with the CV group (mean +/- sem: CV, 1.8 +/- 0.1; late open lung,1.9 +/- 0.1; and early open lung, 2.2 +/- 0.1l). In the CV group, 37% of the patients were hypoxic on the third day after extubation, compared with none of the patients in both OLC groups. After cardiac surgery, earlier application of OLC resulted in a significantly higher FRC and fewer episodes of hypoxemia than with CV after extubation.

Data acquisition using the 168/E. [CERN ISR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carroll, J.T.; Cittolin, S.; Demoulin, M.

1983-03-01

Event sizes and data rates at the CERN anti p p collider compose a formidable environment for a high level trigger. A system using three 168/E processors for experiment UA1 real-time event selection is described. With 168/E data memory expanded to 512K bytes, each processor holds a complete event allowing a FORTRAN trigger algorithm access to data from the entire detector. A smart CAMAC interface reads five Remus branches in parallel transferring one word to the target processor every 0.5 ..mu..s. The NORD host computer can simultaneously read an accepted event from another processor.

Open-RAC: Open-Design, Recirculating and Auto-Cleaning Zebrafish Maintenance System.

PubMed

Nema, Shubham; Bhargava, Yogesh

2017-08-01

Zebrafish is a vertebrate animal model. Their maintenance in large number under laboratory conditions is a daunting task. Commercially available recirculating zebrafish maintenance systems are used to efficiently handle the tasks of automatic sediment cleaning from zebrafish tanks with minimal waste of water. Due to their compact nature, they also ensure the maximal use of available lab space. However, the high costs of commercial systems present a limitation to researchers with limited funds. A cost-effective zebrafish maintenance system with major features offered by commercially available systems is highly desirable. Here, we describe a compact and recirculating zebrafish maintenance system. Our system is composed of cost-effective components, which are available in local markets and/or can be procured via online vendors. Depending on the expertise of end users, the system can be assembled in 2 days. The system is completely customizable as it offers geometry independent zebrafish tanks that are capable of auto-cleaning the sediments. Due to these features, we called our setup as Open-RAC (Open-design, Recirculating and Auto-Cleaning zebrafish maintenance system). Open-RAC is a cost-effective and viable alternative to the currently available zebrafish maintenance systems. Thus, we believe that the use of Open-RAC could promote the zebrafish research by removing the cost barrier for researchers.

A Tony Thomas-Inspired Guide to INSPIRE

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Connell, Heath B.; /Fermilab

2010-04-01

The SPIRES database was created in the late 1960s to catalogue the high energy physics preprints received by the SLAC Library. In the early 1990s it became the first database on the web and the first website outside of Europe. Although indispensible to the HEP community, its aging software infrastructure is becoming a serious liability. In a joint project involving CERN, DESY, Fermilab and SLAC, a new database, INSPIRE, is being created to replace SPIRES using CERN's modern, open-source Invenio database software. INSPIRE will maintain the content and functionality of SPIRES plus many new features. I describe this evolution frommore » the birth of SPIRES to the current day, noting that the career of Tony Thomas spans this timeline.« less

Long-term survival following open repair of ruptured abdominal aortic aneurysm.

PubMed

Englund, Raymond; Katib, Nedal

2017-05-01

Long-term results for patients being managed for ruptured compared to elective abdominal aortic aneurysms (AAA) are unclear. We hypothesize that patients who survive 30 days or more following repair of ruptured AAA (RAAA) performed by open technique have a life expectancy no different to those patients surviving 30 days or more following elective AAA repair, or compared to a general age-matched population. Between 1987 and December 2014, 620 consecutive patients were treated by the principal author for aortic aneurysmal disease. Two subgroups were selected from this population, elective open abdominal repair (215) and RAAA open repair (105). Comparable age-matched life curves with the general population were used from the Australian Bureau of Statistics for each patient according to gender, age and date of presentation. Statistical comparison was by Kaplan-Meier survival analysis. Both the open and RAAA groups were well matched for age and sex. There was no statistical difference between RAAA survival and an age-matched population P = 0.23, or was there any difference between open repair and an age-matched population, P = 0.1. Survival curves for RAAA and open repair were similar, P = 0.98. For elective open repair 1-, 5-, 10-, 15- and 20-year survival was 93.6, 71.2, 40, 17 and 2% respectively. Corresponding results for RAAA were 92.5, 74, 36.7, 13.5 and 5% respectively. Open AAA repair for RAAA or elective aneurysm treatment restores predicted life expectancy for those patients surviving 30 days or more and is therefore a durable method of treatment for this condition. © 2016 Royal Australasian College of Surgeons.

Continuous, daily levonorgestrel/ethinyl estradiol vs. 21-day, cyclic levonorgestrel/ethinyl estradiol: efficacy, safety and bleeding in a randomized, open-label trial.

PubMed

Teichmann, Alexander; Apter, Dan; Emerich, Janusz; Greven, Klaus; Klasa-Mazurkiewicz, Dagmara; Melis, Giambi B; Spaczynski, Marek; Grubb, Gary S; Constantine, Ginger D; Spielmann, Daniele

2009-12-01

This Phase 3, randomized, open-label, multicenter study conducted at 44 sites in Europe evaluated the safety and efficacy of a continuous, daily regimen of levonorgestrel (LNG) 90 mcg/ethinyl estradiol (EE) 20 mcg compared with a 21-day, cyclic LNG 100 mcg/EE 20 mcg regimen. Three hundred twenty-three healthy women were randomized to continuous LNG 90 mcg/EE 20 mcg and 318 subjects to cyclic LNG 100 mcg/EE 20 mcg for 1 year (13 pill packs). Pearl index, adverse event (AE) incidence and bleeding profiles were assessed. No pregnancies occurred with the continuous oral contraceptive (OC) (Pearl index=0.00). As the study progressed, the percentage of women who achieved amenorrhea during each 28-day pill pack increased: 40% at pill pack 7, 53% at pill pack 13. The percentage of women with no bleeding [with or without spotting (defined as not requiring sanitary protection)] was 50%, 69% and 79% at pill packs 3, 7 and 13, respectively. The incidence of AEs was similar to that of the cyclic OC (except for metrorrhagia and vaginal bleeding in the first 6 months). Continuous LNG 90 mcg/EE 20 mcg was shown to be a safe and effective OC in this direct comparison to a cyclic OC. Suppression of menses and the potential for no bleeding requiring sanitary protection may be provided by this continuous, low-dose OC.

Mapping Remote and Multidisciplinary Learning Barriers: Lessons from "Challenge-Based Innovation" at CERN

ERIC Educational Resources Information Center

Jensen, Matilde Bisballe; Utriainen, Tuuli Maria; Steinert, Martin

2018-01-01

This paper presents the experienced difficulties of students participating in the multidisciplinary, remote collaborating engineering design course challenge-based innovation at CERN. This is with the aim to identify learning barriers and improve future learning experiences. We statistically analyse the rated differences between distinct design…

Industry Day Workshops | Energy Systems Integration Facility | NREL

Science.gov Websites

, 2017: Siemens-OMNETRIC Industry Day OMNETRIC Group demonstrated a distributed control hierarchy, based Systems Integration, NREL OMNETRIC Group: Grid Edge Communications and Control Utilizing an OpenFMB NREL Murali Baggu, Manager, Power Systems Operations and Control Group, NREL Santosh Veda, Research

Open Standards, Open Source, and Open Innovation: Harnessing the Benefits of Openness

ERIC Educational Resources Information Center

Committee for Economic Development, 2006

2006-01-01

Digitization of information and the Internet have profoundly expanded the capacity for openness. This report details the benefits of openness in three areas--open standards, open-source software, and open innovation--and examines the major issues in the debate over whether openness should be encouraged or not. The report explains each of these…

Opening up Library Automation Software

ERIC Educational Resources Information Center

Breeding, Marshall

2009-01-01

Throughout the history of library automation, the author has seen a steady advancement toward more open systems. In the early days of library automation, when proprietary systems dominated, the need for standards was paramount since other means of inter-operability and data exchange weren't possible. Today's focus on Application Programming…

Treatment of complicated urinary tract infection and acute pyelonephritis by short-course intravenous levofloxacin (750 mg/day) or conventional intravenous/oral levofloxacin (500 mg/day): prospective, open-label, randomized, controlled, multicenter, non-inferiority clinical trial.

PubMed

Ren, Hong; Li, Xiao; Ni, Zhao-Hui; Niu, Jian-Ying; Cao, Bin; Xu, Jie; Cheng, Hong; Tu, Xiao-Wen; Ren, Ai-Min; Hu, Ying; Xing, Chang-Ying; Liu, Ying-Hong; Li, Yan-Feng; Cen, Jun; Zhou, Rong; Xu, Xu-Dong; Qiu, Xiao-Hui; Chen, Nan

2017-03-01

To compare the efficacy and safety of short-course intravenous levofloxacin (LVFX) 750 mg with a conventional intravenous/oral regimen of LVFX 500 mg in patients from China with complicated urinary tract infections (cUTIs) and acute pyelonephritis (APN). This was a prospective, open-label, randomized, controlled, multicenter, non-inferiority clinical trial. Patients with cUTI and APN were randomly assigned to a short-course therapy group (intravenous LVFX at750 mg/day for 5 days) or a conventional therapy group (intravenous/oral regimen of LVFX at 500 mg/day for 7-14 days). The clinical, laboratory, and microbiological results were evaluated for efficacy and safety. The median dose of LVFX was 3555.4 mg in the short-course therapy group and 4874.2 mg in the conventional therapy group. Intention-to-treat analysis indicated the clinical effectiveness in the short-course therapy group (89.87%, 142/158) was non-inferior to that in the conventional therapy group (89.31%, 142/159). The microbiological effectiveness rates were also similar (short-course therapy: 89.55%, 60/67; conventional therapy: 86.30%, 63/73; p > 0.05). There were no significant differences in other parameters, including clinical and microbiological recurrence rates. The incidence of adverse effects and drug-related adverse effects were also similar for the short-course therapy group (21.95%, 36/164; 18.90%, 31/164) and the conventional therapy group (23.03%, 38/165; 15.76%, 26/165). Patients with cUTIs and APN who were given short-course LVFX therapy and conventional LVFX therapy had similar outcomes in clinical and microbiological efficacy, tolerance, and safety. The short-course therapy described here is a more convenient alternative to the conventional regimen with potential implication in anti-resistance and cost saving.

Solar Home Tour and Exhibitor Showcase Open Doors to Renewable Energy

Science.gov Websites

Information Home Tour and Exhibitor Showcase Open Doors to Renewable Energy Information Golden energy efficiency products and services. The Exhibitor Showcase is open for two days at the NREL Visitors . Oct. 13. The Exhibitor Showcase is free and open to the public. The Denver-area self-guided home tour

Endoscopic versus Open Bursectomy for Prepatellar and Olecranon Bursitis

PubMed Central

Meric, Gokhan; Sargin, Serdar; Atik, Aziz; Ulusal, Ali Engin

2018-01-01

Objectives Bursitis of the olecranon and the patella are not rare disorders, and conservative management is successful in most cases. However, when patients do not respond to conservative treatment, open excisional surgery or, recently, endoscopic bursectomy, can be used. The aim of this study was to evaluate the results of open and endoscopic treatments of olecranon and prepatellar bursitis. Patients and methods Forty-nine patients (37 male and 12 female), who were treated with endoscopic bursectomy (25 patients) or open bursectomy (24 patients) were included in this study. Thirty patients had olecranon bursitis, while 19 patients had prepatellar bursitis. The patients’ average age was 61.1 ± 12.3 (range 33-81) years. All of the patients’ hospitalization and surgery times were recorded. The satisfaction of the patients was evaluated with a satisfaction scoring system, as well as by evaluating residual pain, the range of joint movement, and the cosmetic results of the procedure. Results The average follow-up time was 16 ± 9 months (range 12–27). The median operation time was 23.2 ± 3.5 minutes for the endoscopic bursectomy group and 26.4 ± 6.8 minutes for the open bursectomy group. The median hospitalization time was 0.56 ± 0.5 days (range 0-1 day) for the endoscopic group and 1 ± 0 days for the open bursectomy group (P<0.01). According to the patient satisfaction questionnaire, the endoscopic bursectomy group’s score was 8.5 ± 1.3 (range 5-10), and the open bursectomy group’s score was 5.29 ± 1.8 (range 1-9) (P<0.01). Conclusion Endoscopic bursectomy is a time-saving and efficient surgical treatment option for patients with prepatellar and olecranon bursitis. PMID:29805943

Endoscopic versus Open Bursectomy for Prepatellar and Olecranon Bursitis.

PubMed

Meric, Gokhan; Sargin, Serdar; Atik, Aziz; Budeyri, Aydin; Ulusal, Ali Engin

2018-03-27

Objectives Bursitis of the olecranon and the patella are not rare disorders, and conservative management is successful in most cases. However, when patients do not respond to conservative treatment, open excisional surgery or, recently, endoscopic bursectomy, can be used. The aim of this study was to evaluate the results of open and endoscopic treatments of olecranon and prepatellar bursitis. Patients and methods Forty-nine patients (37 male and 12 female), who were treated with endoscopic bursectomy (25 patients) or open bursectomy (24 patients) were included in this study. Thirty patients had olecranon bursitis, while 19 patients had prepatellar bursitis. The patients' average age was 61.1 ± 12.3 (range 33-81) years. All of the patients' hospitalization and surgery times were recorded. The satisfaction of the patients was evaluated with a satisfaction scoring system, as well as by evaluating residual pain, the range of joint movement, and the cosmetic results of the procedure. Results The average follow-up time was 16 ± 9 months (range 12-27). The median operation time was 23.2 ± 3.5 minutes for the endoscopic bursectomy group and 26.4 ± 6.8 minutes for the open bursectomy group. The median hospitalization time was 0.56 ± 0.5 days (range 0-1 day) for the endoscopic group and 1 ± 0 days for the open bursectomy group (P<0.01). According to the patient satisfaction questionnaire, the endoscopic bursectomy group's score was 8.5 ± 1.3 (range 5-10), and the open bursectomy group's score was 5.29 ± 1.8 (range 1-9) (P<0.01). Conclusion Endoscopic bursectomy is a time-saving and efficient surgical treatment option for patients with prepatellar and olecranon bursitis.

34 CFR 300.11 - Day; business day; school day.

Code of Federal Regulations, 2012 CFR

2012-07-01

... has the same meaning for all children in school, including children with and without disabilities... 34 Education 2 2012-07-01 2012-07-01 false Day; business day; school day. 300.11 Section 300.11... CHILDREN WITH DISABILITIES General Definitions Used in This Part § 300.11 Day; business day; school day. (a...

34 CFR 300.11 - Day; business day; school day.

Code of Federal Regulations, 2014 CFR

2014-07-01

... has the same meaning for all children in school, including children with and without disabilities... 34 Education 2 2014-07-01 2013-07-01 true Day; business day; school day. 300.11 Section 300.11... CHILDREN WITH DISABILITIES General Definitions Used in This Part § 300.11 Day; business day; school day. (a...

34 CFR 300.11 - Day; business day; school day.

Code of Federal Regulations, 2013 CFR

2013-07-01

... has the same meaning for all children in school, including children with and without disabilities... 34 Education 2 2013-07-01 2013-07-01 false Day; business day; school day. 300.11 Section 300.11... CHILDREN WITH DISABILITIES General Definitions Used in This Part § 300.11 Day; business day; school day. (a...

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

The space shuttle Endeavour is seen as workers prepare for the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

STS-90 Day 01 Highlights

NASA Technical Reports Server (NTRS)

1998-01-01

On this first day of the STS-90 mission, the flight crew, Cmdr. Richard A. Searfoss, Pilot Scott D. Altman, and Mission Specialists Richard M. Linnehan, Dafydd Rhys Williams and Kathryn P. Hire, and Payload Specialists Jay C. Buckey and James A. Pawelczyk, can be seen performing pre-launch activities such as eating the traditional breakfast, crew suit-up, and the ride out to the launch pad. Also, included are various panoramic views of the shuttle on the pad. The crew is readied in the white room' for their mission. After the closing of the hatch and arm retraction, launch activities are shown including countdown, engine ignition, launch, and the separation of the Solid Rocket Boosters. The shuttle's payload bay doors are then opened in anticipation of the 16-day scientific mission. The astronauts then are seen readying the Spacelab module for various experiments.

Outcomes of mechanical stapling for postlaryngectomy open pharyngotomy closure.

PubMed

Paddle, Paul; Husain, Inna; McHugh, Lauren; Franco, Ramon

2017-03-01

A total laryngectomy (TL) is performed as a primary or salvage therapy for laryngeal carcinoma. Pharyngotomy closure after TL is typically performed using manual sutures. Automatic stapling devices are routinely used in thoracoabdominal surgery, but have not been widely accepted for use in pharyngotomy closure. Previously described closed stapling techniques of pharyngeal closure do not allow direct evaluation of surgical margins and are limited to endolaryngeal disease. We describe an open technique for pharyngotomy closure using a mechanical stapling device. Retrospective review. A review was conducted of 16 total laryngectomies performed from May 2008 to August 2015 utilizing an Ethicon Endopath ETS Compact-Flex 45 stapler. Sixteen patients (15 male, one female), mean age 69 years, received open TL (14 salvage, two primary) with endostapler pharyngeal closure and primary tracheoesophageal puncture (TEP). Surgical time averaged 218 minutes. Median time to swallowing was 4 days (range, 2-240 days) and mean hospital stay 6 days (range, 3-10 days). Fistula incidence was 31% (5/16) overall and 36% (5/14) in the postradiation patients. Mechanical stapling is a simple method for postlaryngectomy open pharyngotomy closure. This technique allows evaluation of margins, easy primary TEP, and the opportunity for early swallowing and shorter hospital stays. In addition, it can be performed for closure of salvage laryngectomies with rates of fistula formation similar to that found in the literature using suture closure techniques. Future studies are necessary to compare oncological results and surgical complications between the open and closed stapling techniques and to traditional suture closure. 4 Laryngoscope, 127:605-610, 2017. © 2016 The American Laryngological, Rhinological and Otological Society, Inc.

Opening Health Data: What Do Researchers Want? Early Experiences With New York's Open Health Data Platform.

PubMed

Martin, Erika G; Helbig, Natalie; Birkhead, Guthrie S

2015-01-01

Governments are rapidly developing open data platforms to improve transparency and make information more accessible. New York is a leader, with currently the only state platform devoted to health. Although these platforms could build public health departments' capabilities to serve more researchers, agencies have little guidance on releasing meaningful and usable data. Structured focus groups with researchers and practitioners collected stakeholder feedback on potential uses of open health data and New York's open data strategy. Researchers and practitioners attended a 1-day November 2013 workshop on New York State's open health data resources. After learning about the state's open data platform and vision for open health data, participants were organized into 7 focus groups to discuss the essential elements of open data sets, practical challenges to obtaining and using health data, and potential uses of open data. Participants included 33 quantitative health researchers from State University of New York campuses and private partners and 10 practitioners from the New York State Department of Health. There was low awareness of open data, with 67% of researchers reporting never using open data portals prior to the workshop. Participants were interested in data sets that were geocoded, longitudinal, or aggregated to small area granularity and capabilities to link multiple data sets. Multiple environmental conditions and barriers hinder their capacity to use health data for research. Although open data platforms cannot address all barriers, they provide multiple opportunities for public health research and practice, and participants were overall positive about the state's efforts to release open data. Open data are not ideal for some researchers because they do not contain individually identifiable data, indicating a need for tiered data release strategies. However, they do provide important new opportunities to facilitate research and foster collaborations among

Habituation of medaka (Oryzias latipes) demonstrated by open-field testing.

PubMed

Matsunaga, Wataru; Watanabe, Eiji

2010-10-01

Habituation to novel environments is frequently studied to analyze cognitive phenotypes in animals, and an open-field test is generally conducted to investigate the changes that occur in animals during habituation. The test has not been used in behavioral studies of medaka (Oryzias latipes), which is recently being used in behavioral research. Therefore, we examined the open-field behavior of medaka on the basis of temporal changes in 2 conventional indexes of locomotion and position. The findings of our study clearly showed that medaka changed its behavior through multiple temporal phases as it became more familiar with new surroundings; this finding is consistent with those of other ethological studies in animals. During repeated open-field testing on 2 consecutive days, we observed that horizontal locomotion on the second day was less than that on the first day, which suggested that habituation is retained in fish for days. This temporal habituation was critically affected by water factors or visual cues of the tank, thereby suggesting that fish have spatial memory of their surroundings. Thus, the data from this study will afford useful fundamental information for behavioral phenotyping of medaka and for elucidating cognitive phenotypes in animals. Copyright (c) 2010 Elsevier B.V. All rights reserved.

Should we use closed or open infusion containers for prevention of bloodstream infections?

PubMed

Rangel-Frausto, Manuel S; Higuera-Ramirez, Francisco; Martinez-Soto, Jose; Rosenthal, Victor D

2010-02-02

Hospitalized patients in critical care settings are at risk for bloodstream infections (BSI). Most BSIs originate from a central line (CL), and they increase length of stay, cost, and mortality. Open infusion containers may increase the risk of contamination and administration-related (CLAB) because they allow the entry of air into the system, thereby also providing an opportunity for microbial entry. Closed infusion containers were designed to overcome this flaw. However, open infusion containers are still widely used throughout the world.The objective of the study was to determine the effect of switching from open (glass, burettes, and semi-rigid) infusion containers to closed, fully collapsible, plastic infusion containers (Viaflex) on the rate and time to onset of central line-associated bloodstream infections CLABs. An open label, prospective cohort, active healthcare-associated infection surveillance, sequential study was conducted in four ICUs in Mexico. Centers for Disease Control National Nosocomial Infections Surveillance Systems definitions were used to define device-associated infections. A total of 1,096 adult patients who had a central line in place for >24 hours were enrolled. The CLAB rate was significantly higher during the open versus the closed container period (16.1 versus 3.2 CLAB/1000 central line days; RR = 0.20, 95% CI = 0.11-0.36, P < 0.0001). The probability of developing CLAB remained relatively constant in the closed container period (1.4% Days 2-4 to 0.5% Days 8-10), but increased in the open container period (4.9% Days 2-4 to 5.4% Days 8-10). The chance of acquiring a CLAB was significantly decreased (81%) in the closed container period (Cox proportional hazard ratio 0.19, P < 0.0001). Mortality was statistically significantly lower during the closed versus the open container period (23.4% versus 16.1%; RR = 0.69, 95% CI = 0.54-0.88, P < 0.01). Closed infusion containers significantly reduced CLAB rate, the probability of acquiring

Day occupation is associated with psychopathology for adolescents and young adults with Down syndrome.

PubMed

Foley, Kitty-Rose; Jacoby, Peter; Einfeld, Stewart; Girdler, Sonya; Bourke, Jenny; Riches, Vivienne; Leonard, Helen

2014-10-03

Young adults with Down syndrome experience increased rates of emotional and behavioural problems compared with the general population. Most adolescents with Down syndrome living in Western Australia participate in sheltered employment as their main day occupation. Relationship between day occupation and changes in behaviour has not been examined. Therefore, the aim of this research was to explore any relationship between post school day occupations and changes in the young person's behaviour. The Down syndrome Needs Opinion Wishes database was used for case ascertainment of young adults aged 15 to 32 years with Down syndrome. Families of 118 young people in this population-based database completed questionnaires in 2004, 2009 and 2011. The questionnaires addressed both young person characteristics such as age, gender, presence of impairments, behaviour, functioning in activities of daily living, and family characteristics such as income and family functioning. Post-school day occupations in which the young people were participating included open and sheltered employment, training and day recreation programs. Change in behaviour of young adults who remained in the same post-school day occupation from 2009 to 2011 (n = 103) were examined in a linear regression model adjusting for confounding variables including age, gender, prior functioning and behaviour in 2004 and family income. In comparison to those young adults attending open employment from 2009 to 2011, those attending day recreation programs were reported to experience worsening in behaviour both in the unadjusted (effect size -0.14, 95% CI -0.24, -0.05) and adjusted models (effect size -0.15, 95% CI -0.29, -0.01). We found that the behaviour of those participating in open employment improved compared to those attending other day occupations. Further examination of the direction of this association is required.

Take Your Child to Work Day Shows Children that Science Is Fun | Poster

Cancer.gov

There’s still time to register your child for NCI at Frederick’s annual Take Your Child to Work Day, which will be held on Wednesday, June 27. Children who attend will be able to choose from nearly 30 activities this year. Several programs are scheduled to occur at various locations throughout the day, while others will be open on a “come as you please” basis all day long.

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

California Governor Jerry Brown speaks from a podium underneath the space shuttle Endeavour during the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

A police officer is seen underneath the wing of the space shuttle Endeavour during the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

Mayor of Los Angeles Antonio Villaraigosa addresses a class of fourth graders during the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Effect of Azilsartan on Day-to-Day Variability in Home Blood Pressure: A Prospective Multicenter Clinical Trial.

PubMed

Miyoshi, Toru; Suetsuna, Ryoji; Tokunaga, Naoto; Kusaka, Masayasu; Tsuzaki, Ryuichiro; Koten, Kazuya; Kunihisa, Kohno; Ito, Hiroshi

2017-07-01

The blood pressure variability (BPV) such as visit-to-visit, day-by-day, and ambulatory BPV has been also shown to be a risk of future cardiovascular events. However, the effects of antihypertensive therapy on BPV remain unclear. The purpose of this study was to evaluate the effect of azilsartan after switching from another angiotensin II receptor blocker (ARB) on day-to-day BPV in home BP monitoring. This prospective, multicenter, open-labeled, single-arm study included 28 patients undergoing treatment with an ARB, which was switched to azilsartan after enrollment. The primary outcome was the change in the mean of the standard deviation and the coefficient of variation of morning home BP for 5 consecutive days from baseline to the 24-week follow-up. The secondary outcome was the change in arterial stiffness measured by the cardio-ankle vascular index. The mean BPs in the morning and evening for 5 days did not statistically differ between baseline and 24 weeks. For the morning BP, the means of the standard deviations and coefficient of variation of the systolic BP were significantly decreased from 7.4 ± 3.6 mm Hg to 6.1 ± 3.2 mm Hg and from 5.4±2.7% to 4.6±2.3% (mean ± standard deviation, P = 0.04 and P = 0.04, respectively). For the evening BP, no significant change was observed in the systolic or diastolic BPV. The cardio-ankle vascular index significantly decreased from 8.3 ± 0.8 to 8.1 ± 0.8 (P = 0.03). Switching from another ARB to azilsartan reduced day-to-day BPV in the morning and improved arterial stiffness.

An open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).

PubMed

DeWire, Mariko; Fouladi, Maryam; Turner, David C; Wetmore, Cynthia; Hawkins, Cynthia; Jacobs, Carmen; Yuan, Ying; Liu, Diane; Goldman, Stewart; Fisher, Paul; Rytting, Michael; Bouffet, Eric; Khakoo, Yasmin; Hwang, Eugene I; Foreman, Nicholas; Stewart, Clinton F; Gilbert, Mark R; Gilbertson, Richard; Gajjar, Amar

2015-05-01

Co-expression of ERBB2 and ERBB4, reported in 75% of pediatric ependymomas, correlates with worse overall survival. Lapatinib, a selective ERBB1 and ERBB2 inhibitor has produced prolonged disease stabilization in patients with ependymoma in a phase I study. Bevacizumab exposure in ependymoma xenografts leads to ablation of tumor self-renewing cells, arresting growth. Thus, we conducted an open-label, phase II study of bevacizumab and lapatinib in children with recurrent ependymomas. Patients ≤ 21 years of age with recurrent ependymoma received lapatinib orally twice daily (900 mg/m(2)/dose to the first 10 patients, and then 700 mg/m(2)/dose) and bevacizumab 10 mg/kg intravenously on days 1 and 15 of a 28-day course. Lapatinib serum trough levels were analyzed prior to each course. Total and phosphorylated VEGFR2 expression was measured in peripheral blood mononuclear cells (PBMCs) before doses 1 and 2 of bevacizumab and 24-48 h following dose 2 of bevacizumab. Twenty-four patients with a median age of 10 years (range 2-21 years) were enrolled; 22 were eligible and 20 evaluable for response. Thirteen had anaplastic ependymoma. There were no objective responses; 4 patients had stable disease for ≥ 4 courses (range 4-14). Grade 3 toxicities included rash, elevated ALT, and diarrhea. Grade 4 toxicities included peri-tracheostomy hemorrhage (n = 1) and elevated creatinine phosphokinase (n = 1). The median lapatinib pre-dose trough concentration was 3.72 µM. Although the combination of bevacizumab and lapatinib was well tolerated in children with recurrent ependymoma, it proved ineffective.

Open access to high-level data and analysis tools in the CMS experiment at the LHC

DOE PAGES

Calderon, A.; Colling, D.; Huffman, A.; ...

2015-12-23

The CMS experiment, in recognition of its commitment to data preservation and open access as well as to education and outreach, has made its first public release of high-level data under the CC0 waiver: up to half of the proton-proton collision data (by volume) at 7 TeV from 2010 in CMS Analysis Object Data format. CMS has prepared, in collaboration with CERN and the other LHC experiments, an open-data web portal based on Invenio. The portal provides access to CMS public data as well as to analysis tools and documentation for the public. The tools include an event display andmore » histogram application that run in the browser. In addition a virtual machine containing a CMS software environment along with XRootD access to the data is available. Within the virtual machine the public can analyse CMS data, example code is provided. As a result, we describe the accompanying tools and documentation and discuss the first experiences of data use.« less

Day-to-Day Variability in Self-Reported Cigarettes Per Day.

PubMed

Hughes, John R; Shiffman, Saul; Naud, Shelly; Peters, Erica N

2017-09-01

Nicotine addiction theory predicts small day-to-day variability in cigarettes/day (CPD) whereas social learning theory predicts large variability. A description of the variability in CPD over multiple days is not available. We conducted secondary analyses of two natural history studies with daily smokers-one of smokers not intending to quit, and one of smokers intending to quit sometime in the next 3 months. In the former, smokers recorded their smoking during the day by Ecological Momentary Assessment, using a palm-top computer. In the latter, participants reported CPD nightly via a phone Interactive Voice Response system. Analyses were based on smokers who reported averaging ≥10 CPD, and on days in which there was no attempt to stop or reduce smoking. Across the two studies, on average, smokers had small changes in day-to-day CPD (mean changes were 2.2 and 2.9 CPD). However a minority averaged changing by ≥5 CPD from one day to the next (7% and 11%), and many changed by ≥5 CPD on at least 10 of the 90 days (8% and 31%). Neither smoking restrictions, dependence, stereotypy ratings, nor interest in quitting predicted variability. Although on average, smokers have little change day-to-day CPD, a substantial minority of smokers often change by 5 CPD from day-to-day. We did not find potential causes of this variability. Across day variability in CPD is larger than implied in prior studies. Determining causes of day-to-day variability should increase our understanding of the determinants of smoking. © The Author 2017. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A Study in Child Care (Case Study from Volume II-A): "A Rolls-Royce of Day Care." Day Care Programs Reprint Series.

ERIC Educational Resources Information Center

O'Farrell, Brigid

The Amalgamated Day Care Center is an independent trust established through a collective bargaining agreement between the Amalgamated Clothing Workers of America, AFL-CIO, and the employers of the garment industry. The free center, open from 6:00 a.m. to 6:00 p.m., is located near the Chicago garment industries to minimize transportation problems…

Outcomes of laparoscopic and open surgery in children with and without congenital heart disease.

PubMed

Chu, David I; Tan, Jonathan M; Mattei, Peter; Simpao, Allan F; Costarino, Andrew T; Shukla, Aseem R; Rossano, Joseph W; Tasian, Gregory E

2017-11-17

Children with congenital heart disease (CHD) often require noncardiac surgery. We compared outcomes following open and laparoscopic intraabdominal surgery among children with and without CHD. We performed a retrospective cohort study using the 2013-2015 National Surgical Quality Improvement Project-Pediatrics. We matched 45,012 children <18years old who underwent laparoscopic surgery to 45,012 children who underwent open surgery. We determined the associations between laparoscopic (versus open) surgery and 30-day mortality, in-hospital mortality, 30-day morbidity, and postoperative length-of-stay. Among children with minor CHD, laparoscopic surgery was associated with lower 30-day mortality (Odds Ratio [OR] 0.34 [95% Confidence Interval 0.15-0.79]), inhospital mortality (OR 0.42 [0.22-0.81]) and 30-day morbidity (OR 0.61 [0.50-0.73]). As CHD severity increased, this benefit of laparoscopic surgery decreased for 30-day morbidity (ptrend=0.01) and in-hospital mortality (ptrend=0.05), but not for 30-day mortality (ptrend=0.27). Length-of-stay was shorter for laparoscopic approaches for children at cost of higher readmissions. On subgroup analysis, laparoscopy was associated with lower odds of postoperative blood transfusion in all children. Intraabdominal laparoscopic surgery compared to open surgery is associated with decreased morbidity in patients with no CHD and lower morbidity and mortality in patients with minor CHD, but not in those with more severe CHD. Level III: Treatment Study. Copyright © 2017 Elsevier Inc. All rights reserved.

Mini-open repair of achilles rupture in the national football league.

PubMed

McCullough, Kirk A; Shaw, Christopher M; Anderson, Robert B

2014-01-01

Tears of the Achilles tendon in professional athletes are an infrequent yet devastating injury. Historical studies have demonstrated not only a poor rate of return to competitive play but have also noted significant declines in performance for those able to return. While classic treatment of these injuries in the competitive athlete has been an open, locked suture repair, this article reports on a consecutive series of professional football athletes who underwent mini-open repair. All athletes returned to professional football, with seven out of nine (78%) returning to National Football League (NFL) competition. Average return to play was 273 days (8.9 months), with one athlete returning at 166 days (5.4 months). There have been no reruptures and no sural nerve or wound healing complications. Although limited in number currently, mini-open repair in NFL athletes has allowed successful return to competitive play with no reruptures and a trend toward faster return to play compared with historical open repair outcomes.

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

Vocalist James Ingram sings "I Believe I Can Fly" from underneath the space shuttle Endeavour during the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Determining the structure of Higgs couplings at the CERN LargeHadron Collider.

PubMed

Plehn, Tilman; Rainwater, David; Zeppenfeld, Dieter

2002-02-04

Higgs boson production via weak boson fusion at the CERN Large Hadron Collider has the capability to determine the dominant CP nature of a Higgs boson, via the tensor structure of its coupling to weak bosons. This information is contained in the azimuthal angle distribution of the two outgoing forward tagging jets. The technique is independent of both the Higgs boson mass and the observed decay channel.

Effects of stage of pregnancy on variance components, daily milk yields and 305-day milk yield in Holstein cows, as estimated by using a test-day model.

PubMed

Yamazaki, T; Hagiya, K; Takeda, H; Osawa, T; Yamaguchi, S; Nagamine, Y

2016-08-01

Pregnancy and calving are elements indispensable for dairy production, but the daily milk yield of cows decline as pregnancy progresses, especially during the late stages. Therefore, the effect of stage of pregnancy on daily milk yield must be clarified to accurately estimate the breeding values and lifetime productivity of cows. To improve the genetic evaluation model for daily milk yield and determine the effect of the timing of pregnancy on productivity, we used a test-day model to assess the effects of stage of pregnancy on variance component estimates, daily milk yields and 305-day milk yield during the first three lactations of Holstein cows. Data were 10 646 333 test-day records for the first lactation; 8 222 661 records for the second; and 5 513 039 records for the third. The data were analyzed within each lactation by using three single-trait random regression animal models: one model that did not account for the stage of pregnancy effect and two models that did. The effect of stage of pregnancy on test-day milk yield was included in the model by applying a regression on days pregnant or fitting a separate lactation curve for each days open (days from calving to pregnancy) class (eight levels). Stage of pregnancy did not affect the heritability estimates of daily milk yield, although the additive genetic and permanent environmental variances in late lactation were decreased by accounting for the stage of pregnancy effect. The effects of days pregnant on daily milk yield during late lactation were larger in the second and third lactations than in the first lactation. The rates of reduction of the 305-day milk yield of cows that conceived fewer than 90 days after the second or third calving were significantly (P<0.05) greater than that after the first calving. Therefore, we conclude that differences between the negative effects of early pregnancy in the first, compared with later, lactations should be included when determining the optimal number of days open

Open reduction of nasal bone fractures through an intercartilaginous incision.

PubMed

Kim, Ji Heui; Lee, Jun Ho; Hong, Seok Min; Park, Chan Hum

2013-01-01

Open reduction through an intercartilaginous incision was useful for treating delayed-diagnosed nasal bone fractures because it resulted in a successful outcome with minimal complications. Nasal bone fractures are generally managed with closed reduction, which is usually inadequate and results in airway obstruction with a delayed diagnosis of nasal bone fracture when bone healing and fibrotic adhesions around the bone fragment have progressed. This study investigated the surgical outcome of open reduction through an intercartilaginous incision for delayed-diagnosis nasal bone fractures. The study enrolled 18 patients who underwent open reduction through an intercartilaginous incision to correct delayed-diagnosis nasal bone fractures. Three independent otorhinolaryngologists evaluated the outcomes 4-35 months (average 12.7 months) postoperatively as excellent, fair or poor. The time from injury to surgery was 11-39 days (20-39 days in adults and 11-30 days in children). The 18 cases included 16 primary repairs and two revisions. A Kirschner wire was inserted in six (33.3%) patients who had unstable reduced nasal bones. Postoperatively, l5 (83%) patients had excellent results, two (11%) had fair, and one (6%) had a poor outcome. No patient experienced any complication.

A Comparison of Three Types of Day Care and Nursery School-Home Care.

ERIC Educational Resources Information Center

Prescott, Elizabeth

A study was conducted comparing young children's experiences in three types of day care--closed structure, open structure and family--with their experiences in home care supplemented by part-time nursery school. A total of 112 children, aged 2 to 5, were observed, each for 180-200 minutes. Eighty-four were selected from 15 day care centers, half…

Virtual day of the midwife: a global 'pyjama party'.

PubMed

Stewart, Sarah

2014-06-01

The Virtual International Day of the Midwife (VIDM) (www.vidm.org) is an annual online conference designed to break down traditional barriers to continuing professional development (CPD); provide online opportunities for international midwifery networking; and model open access communication and collaboration practices. Whilst the VIDM is designed to reach midwives all around the world, issues of access to the Internet, language and cultural differences prevent some midwives from attending, especially those who live in resource-poor countries. Nevertheless, the VIDM has successfully demonstrated how CPD can be delivered to midwives in a flexible and cost-effective way, as well as bring them together in a truly global open and collaborative environment.

Taking Energy to the Physics Classroom from the Large Hadron Collider at CERN

ERIC Educational Resources Information Center

Cid, Xabier; Cid, Ramon

2009-01-01

In 2008, the greatest experiment in history began. When in full operation, the Large Hadron Collider (LHC) at CERN will generate the greatest amount of information that has ever been produced in an experiment before. It will also reveal some of the most fundamental secrets of nature. Despite the enormous amount of information available on this…

The n_TOF facility: Neutron beams for challenging future measurements at CERN

NASA Astrophysics Data System (ADS)

Chiaveri, E.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bacak, M.; Balibrea, J.; Barbagallo, M.; Bečvář, F.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brown, A.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Cerutti, F.; Chen, Y. H.; Colonna, N.; Cortés, G.; Cortés-Giraldo, M. A.; Cosentino, L.; Damone, L. A.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Göbel, K.; García, A. R.; Gawlik, A.; Gilardoni, S.; Glodariu, T.; Gonçalves, I. F.; González, E.; Griesmayer, E.; Guerrero, C.; Gunsing, F.; Harada, H.; Heinitz, S.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Kalamara, A.; Kavrigin, P.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Kurtulgil, D.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui-Marco, J.; Meo, S. Lo; Lonsdale, S. J.; Macina, D.; Marganiec, J.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Musumarra, A.; Negret, A.; Nolte, R.; Oprea, A.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, I.; Praena, J.; Quesada, J. M.; Radeck, D.; Rauscher, T.; Reifarth, R.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schumann, D.; Smith, A. G.; Sosnin, N. V.; Stamatopoulos, A.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Woods, P. J.; Wright, T.; Žugec, P.

2017-09-01

The CERN n_TOF neutron beam facility is characterized by a very high instantaneous neutron flux, excellent TOF resolution at the 185 m long flight path (EAR-1), low intrinsic background and coverage of a wide range of neutron energies, from thermal to a few GeV. These characteristics provide a unique possibility to perform high-accuracy measurements of neutron-induced reaction cross-sections and angular distributions of interest for fundamental and applied Nuclear Physics. Since 2001, the n_TOF Collaboration has collected a wealth of high quality nuclear data relevant for nuclear astrophysics, nuclear reactor technology, nuclear medicine, etc. The overall efficiency of the experimental program and the range of possible measurements has been expanded with the construction of a second experimental area (EAR-2), located 20 m on the vertical of the n_TOF spallation target. This upgrade, which benefits from a neutron flux 30 times higher than in EAR-1, provides a substantial extension in measurement capabilities, opening the possibility to collect data on neutron cross-section of isotopes with short half-lives or available in very small amounts. This contribution will outline the main characteristics of the n_TOF facility, with special emphasis on the new experimental area. In particular, we will discuss the innovative features of the EAR-2 neutron beam that make possible to perform very challenging measurements on short-lived radioisotopes or sub-mg samples, out of reach up to now at other neutron facilities around the world. Finally, the future perspectives of the facility will be presented.

Effect of Azilsartan on Day-to-Day Variability in Home Blood Pressure: A Prospective Multicenter Clinical Trial

PubMed Central

Miyoshi, Toru; Suetsuna, Ryoji; Tokunaga, Naoto; Kusaka, Masayasu; Tsuzaki, Ryuichiro; Koten, Kazuya; Kunihisa, Kohno; Ito, Hiroshi

2017-01-01

Background The blood pressure variability (BPV) such as visit-to-visit, day-by-day, and ambulatory BPV has been also shown to be a risk of future cardiovascular events. However, the effects of antihypertensive therapy on BPV remain unclear. The purpose of this study was to evaluate the effect of azilsartan after switching from another angiotensin II receptor blocker (ARB) on day-to-day BPV in home BP monitoring. Methods This prospective, multicenter, open-labeled, single-arm study included 28 patients undergoing treatment with an ARB, which was switched to azilsartan after enrollment. The primary outcome was the change in the mean of the standard deviation and the coefficient of variation of morning home BP for 5 consecutive days from baseline to the 24-week follow-up. The secondary outcome was the change in arterial stiffness measured by the cardio-ankle vascular index. Results The mean BPs in the morning and evening for 5 days did not statistically differ between baseline and 24 weeks. For the morning BP, the means of the standard deviations and coefficient of variation of the systolic BP were significantly decreased from 7.4 ± 3.6 mm Hg to 6.1 ± 3.2 mm Hg and from 5.4±2.7% to 4.6±2.3% (mean ± standard deviation, P = 0.04 and P = 0.04, respectively). For the evening BP, no significant change was observed in the systolic or diastolic BPV. The cardio-ankle vascular index significantly decreased from 8.3 ± 0.8 to 8.1 ± 0.8 (P = 0.03). Conclusions Switching from another ARB to azilsartan reduced day-to-day BPV in the morning and improved arterial stiffness. PMID:28611863

AMS data production facilities at science operations center at CERN

NASA Astrophysics Data System (ADS)

Choutko, V.; Egorov, A.; Eline, A.; Shan, B.

2017-10-01

The Alpha Magnetic Spectrometer (AMS) is a high energy physics experiment on the board of the International Space Station (ISS). This paper presents the hardware and software facilities of Science Operation Center (SOC) at CERN. Data Production is built around production server - a scalable distributed service which links together a set of different programming modules for science data transformation and reconstruction. The server has the capacity to manage 1000 paralleled job producers, i.e. up to 32K logical processors. Monitoring and management tool with Production GUI is also described.

Unplanned Robotic-Assisted Conversion-to-Open Colorectal Surgery is Associated with Adverse Outcomes.

PubMed

Lee, Yongjin F; Albright, Jeremy; Akram, Warqaa M; Wu, Juan; Ferraro, Jane; Cleary, Robert K

2018-06-01

Laparoscopic conversion-to-open colorectal surgery is associated with worse outcomes when compared to operations completed without conversion. Consequences of robotic conversion have not yet been determined. The purpose of this study is to compare short-term outcomes of converted robotic colorectal cases with those that are completed without conversion, as well as with cases done by the open approach. The ACS-NSQIP database was queried for patients who underwent robotic completed, robotic converted-to-open, and open colorectal resection between 2012 and 2015. Propensity scores were estimated using gradient-boosted machines and converted to weights. Generalized linear models were fit using propensity score-weighted data. A total of 25,253 patients met inclusion criteria-21,356 (84.5%) open, 3663 (14.5%) robotic completed, and 234 (0.9%) conversions. Conversion rate was 6.0%. Converted cases had significantly higher 30-day mortality rate, higher complication rate, and longer hospital length of stay than completed cases. Converted patients also had significantly higher rates of the following complications: surgical site infections, cardiac complications, deep venous thrombosis, postoperative ileus, postoperative re-intubation, renal failure, and 30-day reoperation. Compared to the open approach, converted patients had significantly more cardiac complications, postoperative reintubation, and longer operating times with no significant difference in 30-day mortality. Unplanned robotic conversion-to-open is associated with worse outcomes than completed cases and outcomes that more closely resemble traditional open colorectal surgery. Patients should be counseled with regard to minimally invasive conversion rates and outcomes. The continued pursuit of technological advancements that decrease the risk for conversion in minimally invasive colorectal surgery is clearly warranted.

Comparison of inflammatory responses following robotic and open colorectal surgery: a prospective study.

PubMed

Zawadzki, Marek; Krzystek-Korpacka, Malgorzata; Gamian, Andrzej; Witkiewicz, Wojciech

2017-03-01

Robotic colorectal surgery continues to rise in popularity, but there remains little evidence on the stress response following the procedure. The aim of this study was to evaluate the inflammatory response to robotic colorectal surgery and compare it with the response generated by open colorectal surgery. This was a prospective nonrandomized comparative study involving 61 patients with colorectal cancer. The evaluation of inflammatory response to either robotic or open colorectal surgery was expressed as changes in interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, tumor necrosis factor-α, C-reactive protein, and procalcitonin during the first three postoperative days. Of the 61 patients, 33 underwent robotic colorectal surgery while 28 had open colorectal surgery. Groups were comparable with respect to age, sex, BMI, cancer stage, and type of resection. The relative increase of interleukin-1 receptor antagonist at 8 h postoperative, compared to baseline, was higher in the open group (P = 0.006). The decrease of interleukin-1 receptor antagonist on postoperative days 1 and 3, compared to the maximum at 8 h, was more pronounced in the open group than in the robotic group (P = 0.008, P = 0.006, respectively), and the relative increase of interleukin-6 at 8 h after incision was higher in the open group (P = 0.007). The relative increase of procalcitonin on postoperative days 1 and 3 was higher in the open group than the robotic group (P < 0.001, P = 0.004, respectively). This study shows that when compared with open colorectal surgery, robotic colorectal surgery results in a less pronounced inflammatory response and more pronounced anti-inflammatory action.

Openly Published Environmental Sensing (OPEnS) | Advancing Open-Source Research, Instrumentation, and Dissemination

NASA Astrophysics Data System (ADS)

Udell, C.; Selker, J. S.

2017-12-01

The increasing availability and functionality of Open-Source software and hardware along with 3D printing, low-cost electronics, and proliferation of open-access resources for learning rapid prototyping are contributing to fundamental transformations and new technologies in environmental sensing. These tools invite reevaluation of time-tested methodologies and devices toward more efficient, reusable, and inexpensive alternatives. Building upon Open-Source design facilitates community engagement and invites a Do-It-Together (DIT) collaborative framework for research where solutions to complex problems may be crowd-sourced. However, barriers persist that prevent researchers from taking advantage of the capabilities afforded by open-source software, hardware, and rapid prototyping. Some of these include: requisite technical skillsets, knowledge of equipment capabilities, identifying inexpensive sources for materials, money, space, and time. A university MAKER space staffed by engineering students to assist researchers is one proposed solution to overcome many of these obstacles. This presentation investigates the unique capabilities the USDA-funded Openly Published Environmental Sensing (OPEnS) Lab affords researchers, within Oregon State and internationally, and the unique functions these types of initiatives support at the intersection of MAKER spaces, Open-Source academic research, and open-access dissemination.

News Conference: Serbia hosts teachers' seminar Resources: Teachers TV website closes for business Festival: Science takes to the stage in Denmark Research: How noise affects learning in secondary schools CERN: CERN visit inspires new teaching ideas Education: PLS aims to improve perception of science for school students Conference: Scientix conference discusses challenges in science education

NASA Astrophysics Data System (ADS)

2011-07-01

Conference: Serbia hosts teachers' seminar Resources: Teachers TV website closes for business Festival: Science takes to the stage in Denmark Research: How noise affects learning in secondary schools CERN: CERN visit inspires new teaching ideas Education: PLS aims to improve perception of science for school students Conference: Scientix conference discusses challenges in science education

News Particle Physics: ATLAS unveils mural at CERN Prize: Corti Trust invites essay entries Astrophysics: CERN holds cosmic-ray conference Researchers in Residence: Lord Winston returns to school Music: ATLAS scientists record physics music Conference: Champagne flows at Reims event Competition: Students triumph at physics olympiad Teaching: Physics proves popular in Japanese schools Forthcoming Events

NASA Astrophysics Data System (ADS)

2011-01-01

Particle Physics: ATLAS unveils mural at CERN Prize: Corti Trust invites essay entries Astrophysics: CERN holds cosmic-ray conference Researchers in Residence: Lord Winston returns to school Music: ATLAS scientists record physics music Conference: Champagne flows at Reims event Competition: Students triumph at physics olympiad Teaching: Physics proves popular in Japanese schools Forthcoming Events

Development and methods for an open-sourced data visualization tool

USDA-ARS?s Scientific Manuscript database

This paper presents an open source on-demand web tool, which is specifically addressed to scientists and researchers that are non-expert in converting time series data into a time surface visualization. Similar to a GIS environment the time surface shows time on two axes; time of day vs. day of year...

36 CFR 1280.92 - When are the Presidential library museums open to the public?

Code of Federal Regulations, 2011 CFR

2011-07-01

... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving, December...

36 CFR 1280.92 - When are the Presidential library museums open to the public?

Code of Federal Regulations, 2012 CFR

2012-07-01

... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving, December...

36 CFR 1280.92 - When are the Presidential library museums open to the public?

Code of Federal Regulations, 2014 CFR

2014-07-01

... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving, December...

The 2015 Bioinformatics Open Source Conference (BOSC 2015).

PubMed

Harris, Nomi L; Cock, Peter J A; Lapp, Hilmar; Chapman, Brad; Davey, Rob; Fields, Christopher; Hokamp, Karsten; Munoz-Torres, Monica

2016-02-01

The Bioinformatics Open Source Conference (BOSC) is organized by the Open Bioinformatics Foundation (OBF), a nonprofit group dedicated to promoting the practice and philosophy of open source software development and open science within the biological research community. Since its inception in 2000, BOSC has provided bioinformatics developers with a forum for communicating the results of their latest efforts to the wider research community. BOSC offers a focused environment for developers and users to interact and share ideas about standards; software development practices; practical techniques for solving bioinformatics problems; and approaches that promote open science and sharing of data, results, and software. BOSC is run as a two-day special interest group (SIG) before the annual Intelligent Systems in Molecular Biology (ISMB) conference. BOSC 2015 took place in Dublin, Ireland, and was attended by over 125 people, about half of whom were first-time attendees. Session topics included "Data Science;" "Standards and Interoperability;" "Open Science and Reproducibility;" "Translational Bioinformatics;" "Visualization;" and "Bioinformatics Open Source Project Updates". In addition to two keynote talks and dozens of shorter talks chosen from submitted abstracts, BOSC 2015 included a panel, titled "Open Source, Open Door: Increasing Diversity in the Bioinformatics Open Source Community," that provided an opportunity for open discussion about ways to increase the diversity of participants in BOSC in particular, and in open source bioinformatics in general. The complete program of BOSC 2015 is available online at http://www.open-bio.org/wiki/BOSC_2015_Schedule.

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

David D. McBride, director of NASA's Dryden Flight Research Center, speaks from a podium underneath the space shuttle Endeavour during the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

President and CEO of the California Science Center Jeffrey N. Rudolph speaks from a podium underneath the space shuttle Endeavour during the grand opening ceremony for the center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

Members of the Debbie Allen Dance Academy perform “Men in Black” choreographed by the legendary Debbie Allen during the grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

Chief Executive Officer of the Planetary Society, Bill Nye "The Science Guy", acts as emcee from a podium underneath the space shuttle Endeavour during the grand opening ceremony for the center's Samuel Oschin Space Shuttle Endeavour Display Pavilion, Tuesday, Oct. 30, 2012, in Los Angeles. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Measurement of the inclusive jet cross section at the CERN pp collider

NASA Astrophysics Data System (ADS)

Arnison, G.; Albrow, M. G.; Allkofer, O. C.; Astbury, A.; Aubert, B.; Bacci, C.; Batley, J. R.; Bauer, G.; Bettini, A.; Bézaguet, A.; Bock, R. K.; Bos, K.; Buckley, E.; Bunn, J.; Busetto, G.; Catz, P.; Cennini, P.; Centro, S.; Ceradini, F.; Ciapetti, G.; Cittolin, S.; Clarke, D.; Cline, D.; Cochet, C.; Colas, J.; Colas, P.; Corden, M.; Cox, G.; Dallman, D.; Dau, D.; Debeer, M.; Debrion, J. P.; Degiorgi, M.; della Negra, M.; Demoulin, M.; Denby, B.; Denegri, D.; Diciaccio, A.; Dobrzynski, L.; Dorenbosch, J.; Dowell, J. D.; Duchovni, E.; Edgecock, R.; Eggert, K.; Eisenhandler, E.; Ellis, N.; Erhard, P.; Faissner, H.; Fince Keeler, M.; Flynn, P.; Fontaine, G.; Frey, R.; Frühwirth, R.; Garvey, J.; Gee, D.; Geer, S.; Ghesquière, C.; Ghez, P.; Ghio, F.; Giacomelli, P.; Gibson, W. R.; Giraud-Héraud, Y.; Givernaud, A.; Gonidec, A.; Goodman, M.; Grassmann, H.; Grayer, G.; Guryn, W.; Hansl-Kozanecka, T.; Haynes, W.; Haywood, S. J.; Hoffmann, H.; Holthuizen, D. J.; Homer, R. J.; Homer, R. J.; Honma, A.; Jank, W.; Jimack, M.; Jorat, G.; Kalmus, P. I. P.; Karimäri, V.; Keeler, R.; Kenyon, I.; Kernan, A.; Kienzle, W.; Kinnunen, R.; Kozanecki, W.; Kroll, J.; Kryn, D.; Kyberd, P.; Lacava, F.; Laugier, J. P.; Lees, J. P.; Leuchs, R.; Levegrun, S.; Lévêque, A.; Levi, M.; Linglin, D.; Locci, E.; Long, K.; Markiewicz, T.; Markytan, M.; Martin, T.; Maurin, F.; McMahon, T.; Mendiburu, J.-P.; Meneguzzo, A.; Meyer, O.; Meyer, T.; Minard, M.-N.; Mohammadi, M.; Morgan, K.; Moricca, M.; Moser, H.; Mours, B.; Muller, Th.; Nandi, A.; Naumann, L.; Norton, A.; Paoluzi, L.; Pascoli, D.; Pauss, F.; Perault, C.; Piano Mortari, G.; Pietarinen, E.; Pigot, C.; Pimiä, M.; Pitman, D.; Placci, A.; Porte, J.-P.; Radermacher, E.; Ransdell, J.; Redelberger, T.; Reithler, H.; Revol, J. P.; Richman, J.; Rijssenbeek, M.; Rohlf, J.; Rossi, P.; Roberts, C.; Ruhm, W.; Rubbia, C.; Sajot, G.; Salvini, G.; Sass, J.; Sadoulet, B.; Samyn, D.; Savoy-Navarro, A.; Schinzel, D.; Schwartz, A.; Scott, W.; Scott, W.; Shah, T. P.; Sheer, I.; Siotis, I.; Smith, D.; Sobie, R.; Sphicas, P.; Strauss, J.; Streets, J.; Stubenrauch, C.; Summers, D.; Sumorok, K.; Szonczo, F.; Tao, C.; Ten Have, I.; Thompson, G.; Tscheslog, E.; Tuominiemi, J.; van Eijk, B.; Verecchia, P.; Vialle, J. P.; Virdee, T. S.; von der Schmitt, H.; von Schlippe, W.; Vrana, J.; Vuillemin, V.; Wahl, H. D.; Watkins, P.; Wilke, R.; Wilson, J.; Wingerter, I.; Wimpenny, S. J.; Wulz, C.-E.; Wyatt, T.; Yvert, M.; Zacharov, I.; Zaganidis, N.; Zanello, L.; Zotto, P.

1986-05-01

The inclusive jet cross section has been measured in the UA1 experiment at the CERN pp Collider at centre-of-mass energies √s = 546 GeV and √s = 630 eV. The cross sections are found to be consistent with QCD predictions, The observed change in the cross section with the centre-of-mass energy √s is accounted for in terms of xT scaling.

Psychiatric rehabilitation in community-based day centres: motivation and satisfaction.

PubMed

Eklund, Mona; Tjörnstrand, Carina

2013-11-01

This study investigated attendees' motivation and motives for participation in day centres and their satisfaction with the rehabilitation, while also addressing the influence of day centre orientation (work- or meeting-place orientation), gender and age. Ninety-three Swedish day centre attendees participated in a cross-sectional study and completed questionnaires about motivation, motives, and satisfaction with the rehabilitation. Data were analysed with non-parametric statistics. The participants were highly motivated for going to the day centre and set clear goals for their rehabilitation. Female gender, but not age, was associated with stronger motivation. The strongest motives for going to the day centre were getting structure to the day and socializing. Attendees at work-oriented day centres more often expressed that they went there to get structure to the day and gain social status. Satisfaction with the rehabilitation was high, and the most common wishes for further opportunities concerned earning money and learning new things. The rehabilitation largely seemed to meet the attendees' needs, but the findings indicated that further developments were desired, such as participation in work on the open market and more work-like occupations in the day centre, accompanied by some kind of remuneration.

Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial.

PubMed

Kacmarek, Robert M; Villar, Jesús; Sulemanji, Demet; Montiel, Raquel; Ferrando, Carlos; Blanco, Jesús; Koh, Younsuck; Soler, Juan Alfonso; Martínez, Domingo; Hernández, Marianela; Tucci, Mauro; Borges, Joao Batista; Lubillo, Santiago; Santos, Arnoldo; Araujo, Juan B; Amato, Marcelo B P; Suárez-Sipmann, Fernando

2016-01-01

The open lung approach is a mechanical ventilation strategy involving lung recruitment and a decremental positive end-expiratory pressure trial. We compared the Acute Respiratory Distress Syndrome network protocol using low levels of positive end-expiratory pressure with open lung approach resulting in moderate to high levels of positive end-expiratory pressure for the management of established moderate/severe acute respiratory distress syndrome. A prospective, multicenter, pilot, randomized controlled trial. A network of 20 multidisciplinary ICUs. Patients meeting the American-European Consensus Conference definition for acute respiratory distress syndrome were considered for the study. At 12-36 hours after acute respiratory distress syndrome onset, patients were assessed under standardized ventilator settings (FIO2≥0.5, positive end-expiratory pressure ≥10 cm H2O). If Pao2/FIO2 ratio remained less than or equal to 200 mm Hg, patients were randomized to open lung approach or Acute Respiratory Distress Syndrome network protocol. All patients were ventilated with a tidal volume of 4 to 8 ml/kg predicted body weight. From 1,874 screened patients with acute respiratory distress syndrome, 200 were randomized: 99 to open lung approach and 101 to Acute Respiratory Distress Syndrome network protocol. Main outcome measures were 60-day and ICU mortalities, and ventilator-free days. Mortality at day-60 (29% open lung approach vs. 33% Acute Respiratory Distress Syndrome Network protocol, p = 0.18, log rank test), ICU mortality (25% open lung approach vs. 30% Acute Respiratory Distress Syndrome network protocol, p = 0.53 Fisher's exact test), and ventilator-free days (8 [0-20] open lung approach vs. 7 [0-20] d Acute Respiratory Distress Syndrome network protocol, p = 0.53 Wilcoxon rank test) were not significantly different. Airway driving pressure (plateau pressure - positive end-expiratory pressure) and PaO2/FIO2 improved significantly at 24, 48 and 72 hours in patients

Big Bang Day : Physics Rocks

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2009-10-07

Is particle physics the new rock 'n' roll? The fundamental questions about the nature of the universe that particle physics hopes to answer have attracted the attention of some very high profile and unusual fans. Alan Alda, Ben Miller, Eddie Izzard, Dara O'Briain and John Barrowman all have interests in this branch of physics. Brian Cox - CERN physicist, and former member of 90's band D:Ream, tracks down some very well known celebrity enthusiasts and takes a light-hearted look at why this subject can appeal to all of us.

Big Bang Day : Physics Rocks

ScienceCinema

None

2017-12-09

Is particle physics the new rock 'n' roll? The fundamental questions about the nature of the universe that particle physics hopes to answer have attracted the attention of some very high profile and unusual fans. Alan Alda, Ben Miller, Eddie Izzard, Dara O'Briain and John Barrowman all have interests in this branch of physics. Brian Cox - CERN physicist, and former member of 90's band D:Ream, tracks down some very well known celebrity enthusiasts and takes a light-hearted look at why this subject can appeal to all of us.

Measurements and FLUKA Simulations of Bismuth, Aluminium and Indium Activation at the upgraded CERN Shielding Benchmark Facility (CSBF)

NASA Astrophysics Data System (ADS)

Iliopoulou, E.; Bamidis, P.; Brugger, M.; Froeschl, R.; Infantino, A.; Kajimoto, T.; Nakao, N.; Roesler, S.; Sanami, T.; Siountas, A.; Yashima, H.

2018-06-01

The CERN High energy AcceleRator Mixed field (CHARM) facility is situated in the CERN Proton Synchrotron (PS) East Experimental Area. The facility receives a pulsed proton beam from the CERN PS with a beam momentum of 24 GeV/c with 5·1011 protons per pulse with a pulse length of 350 ms and with a maximum average beam intensity of 6.7·1010 protons per second. The extracted proton beam impacts on a cylindrical copper target. The shielding of the CHARM facility includes the CERN Shielding Benchmark Facility (CSBF) situated laterally above the target that allows deep shielding penetration benchmark studies of various shielding materials. This facility has been significantly upgraded during the extended technical stop at the beginning of 2016. It consists now of 40 cm of cast iron shielding, a 200 cm long removable sample holder concrete block with 3 inserts for activation samples, a material test location that is used for the measurement of the attenuation length for different shielding materials as well as for sample activation at different thicknesses of the shielding materials. Activation samples of bismuth, aluminium and indium were placed in the CSBF in September 2016 to characterize the upgraded version of the CSBF. Monte Carlo simulations with the FLUKA code have been performed to estimate the specific production yields of bismuth isotopes (206 Bi, 205 Bi, 204 Bi, 203 Bi, 202 Bi, 201 Bi) from 209 Bi, 24 Na from 27 Al and 115 m I from 115 I for these samples. The production yields estimated by FLUKA Monte Carlo simulations are compared to the production yields obtained from γ-spectroscopy measurements of the samples taking the beam intensity profile into account. The agreement between FLUKA predictions and γ-spectroscopy measurements for the production yields is at a level of a factor of 2.

Astronaut Edwin Aldrin in open hatch of spacecraft during EVA

NASA Technical Reports Server (NTRS)

1966-01-01

Astronaut Edwin Aldrin, pilot for the Gemini 12 flight, stands up in the open hatch of the spacecraft during his extravehicular activity (EVA) on the first day of the four day mission in space. He prepares camera for installation on outside of the spacecraft (63537); Aldrin removes micrometeoroid package for return to the spacecraft (63538).

Opening Reproducible Research

NASA Astrophysics Data System (ADS)

Nüst, Daniel; Konkol, Markus; Pebesma, Edzer; Kray, Christian; Klötgen, Stephanie; Schutzeichel, Marc; Lorenz, Jörg; Przibytzin, Holger; Kussmann, Dirk

2016-04-01

reproduce the original research and hence recreate the original research results (figures, tables), but also facilitates interaction with them as well as their recombination with new data or methods. Building on existing open standards and software, this project develops standards and tools for ERCs, and will demonstrate and evaluate these, focusing on the geosciences domains. The project goes beyond a technical solution for ERCs by evaluating the system from the perspectives of geoscience researchers as participants in a scientific publication process. It will focus on the statistical environment R, but also evaluate larger run time systems captured in virtual environments (Docker containers). ERCs are built upon and integrate well with both established day-to-day workflows of digital research and the scientific publication process. They make research accessible on different levels at any stage to anyone via open web platforms. Other scientists can transfer a compendium of software and tools to their own local environment and collaborate, while others make minimal changes and compare changed results in a web browser. Building on recent advances in mainstream IT, ORR envisions a new architecture for storing, executing and interacting with the original analysis environment alongside the corresponding research data and text. ORR bridges the gap between long-term archives, practical geoscience researchers, as well as publication media. Consequently, the project team seeks input and feedback from researchers working with geospatial data to ensure usable and useful open access publications as well as a publication process that minimizes effort while maximizing usability and re-usability. {References} Pebesma, E., D. Nüst, R. Bivand, 2012. The R software environment in reproducible geoscientific research. Eos, Transactions American Geophysical Union 93, vol 16, p. http://dx.doi.org/10.1029/2012EO160003{163-164}. Opening Reproducible Research project description and website

Electrical properties study under radiation of the 3D-open-shell-electrode detector

NASA Astrophysics Data System (ADS)

Liu, Manwen; Li, Zheng

2018-05-01

Since the 3D-Open-Shell-Electrode Detector (3DOSED) is proposed and the structure is optimized, it is important to study 3DOSED's electrical properties to determine the detector's working performance, especially in the heavy radiation environments, like the Large Hadron Collider (LHC) and it's upgrade, the High Luminosity (HL-LHC) at CERN. In this work, full 3D technology computer-aided design (TCAD) simulations have been done on this novel silicon detector structure. Simulated detector properties include the electric field distribution, the electric potential distribution, current-voltage (I-V) characteristics, capacitance-voltage (C-V) characteristics, charge collection property, and full depletion voltage. Through the analysis of calculations and simulation results, we find that the 3DOSED's electric field and potential distributions are very uniform, even in the tiny region near the shell openings with little perturbations. The novel detector fits the designing purpose of collecting charges generated by particle/light in a good fashion with a well defined funnel shape of electric potential distribution that makes these charges drifting towards the center collection electrode. Furthermore, by analyzing the I-V, C-V, charge collection property and full depletion voltage, we can expect that the novel detector will perform well, even in the heavy radiation environments.

Results of open pararenal abdominal aortic aneurysm repair: single centre series and pooled analysis of literature.

PubMed

van Lammeren, Guus W; Ünlü, Çağdaş; Verschoor, Sjoerd; van Dongen, Eric P; Wille, Jan; van de Pavoordt, Eric Dwm; de Vries-Werson, Debbie Ab; De Vries, Jean-Paul Pm

2017-06-01

Objectives Endovascular treatment of pararenal abdominal aortic aneurysm has gained terrain over the past decade, despite the substantial need for reinterventions during follow-up. However, open repair is still a well-established treatment option. With the current study we report the results of a consecutive series of elective primary open pararenal abdominal aortic aneurysm repair in a tertiary vascular referral centre, combined with an overview of current literature and pooled data analysis of perioperative mortality of open and endovascular pararenal abdominal aortic aneurysm repair. Methods A retrospective analysis of a prospective database of all elective open pararenal abdominal aortic aneurysm repairs in the St. Antonius Hospital between 2005 and 2014 was performed. Primary endpoint was 30-day mortality. Secondary endpoints were 30-day morbidity, new onset dialysis, reintervention free survival, and overall survival during follow-up. Results Between 2005 and 2014, 214 consecutive patients underwent elective open pararenal abdominal aortic aneurysm repair. Mean age was 69.8 (±7.1) years, 82.7% (177/214) were men, and mean abdominal aortic aneurysm diameter was 62 (±11) mm. Thirty-day mortality was 3.4%. Thirty-day morbidity was 27.1%, which predominantly consisted of pneumonia (18.7% (40/214)), cardiac events (3.3% (7/214)), and new onset dialysis (2.8% (6/214)). Estimated five-year overall survival rate was 74.2%. 0.9% (2/214) of patients required abdominal aortic aneurysm-related reintervention, and an additional 2.3% (5/214) required surgical repair of an incisional hernia. Pooled analysis of literature revealed a 30-day mortality of 3.0% for open pararenal repair and 1.9% for fenestrated endovascular repair. Conclusion Open pararenal abdominal aortic aneurysm repair in the era of increasing endovascular options results in acceptable perioperative morbidity and mortality rates. Mid-term reintervention rate is low compared to fenestrated endovascular

Open Versus Closed Septorhinoplasty Approaches for Postoperative Edema and Ecchymosis.

PubMed

Sakallioğlu, Öner; Cingi, Cemal; Polat, Cahit; Soylu, Erkan; Akyigit, Abdulvahap; Soken, Hakan

2015-06-01

The aim of this study was to compare periorbital edema and ecchymosis seen after closed (endonasal) and open (external) septorhinoplasty (SRP). In total, 50 patients undergoing hump extraction and osteotomies were allocated to 2 groups. Group 1 consisted of 25 patients who underwent closed SRP. Group 2 consisted of 25 patients who underwent open SRP. Operation time, amount of intraoperative bleeding, and complications were recorded. Scoring of eyelid edema and periorbital ecchymosis was evaluated on the first, third, and seventh postoperative days using a scale of 0 to 4 by the first author. There was no statistically significant difference between the groups in terms of age, sex, or operation time. No significant difference was observed clinically or statistically in the scores of periorbital edema or ecchymosis between groups 1 and 2 on the first, third, and seventh postoperative days (P > 0.05). The authors observed no clinically or statistically significant difference in comparing periorbital edema and ecchymosis seen after closed and open SRP.

Children's Well-Being in Day Care Centres: An Exploratory Empirical Study.

ERIC Educational Resources Information Center

Mayr, Toni; Ulich, Michaela

1999-01-01

Used educators' ratings to describe preschool children's well-being in day care centers. Identified 11 independent dimensions of well-being: empathic, prosocial behavior; social initiative and vitality; self-assertiveness, openness; pleasure in exploring; coping with stress; positive self-defense; pleasure in sensory experiences;…

[Clinical impact of opening a human milk bank in a neonatal unit].

PubMed

Vázquez-Román, S; Bustos-Lozano, G; López-Maestro, M; Rodríguez-López, J; Orbea-Gallardo, C; Samaniego-Fernández, M; Pallás-Alonso, C R

2014-09-01

The benefits of donor human milk compared with artificial formulas have been well demonstrated; nevertheless the impact in the clinical practice of opening a human milk bank within a neonatal unit has not yet been studied. The main aim of this study was to analyze the impact on the clinical practice of opening a human milk bank in a neonatal unit to provide donor human milk for preterm infants ≤ 32 weeks of gestational age. A before and after study was designed, with the intervention being the opening a human milk bank. Preterm infants ≤ 32 weeks of gestational age born in the Hospital 12 Octubre from July to December 2005 and January to June 2008 (firsts 6 months after opening the human milk bank) were included. After opening the human milk bank, enteral feedings were started 31h before (P<.001), 100ml/kg/day were achieved 59.5h before (P<.001) and 150 ml/kg/day 52 h before (P=.002). Enteral feedings were never started LM with artificial formula, the exposure to formula in the first 15 days of life was reduced from 50% to 16.6%, and it's consumption during the first 28 days of life was significantly reduced. There was a higher consumption of own mother's milk during the hospital stay, and a higher rate of exclusive breastfeeding at hospital discharge (54% vs 40%). The availability of donor human milk has led to quicker progression with enteral feedings and earlier withdrawal of parenteral nutrition. It has reduced the exposure to artificial formulas, and has also increased the intake of own mother's milk during the hospital stay and the rate of exclusive breastfeeding at hospital discharge. Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

Nuclear data activities at the n_TOF facility at CERN

NASA Astrophysics Data System (ADS)

Gunsing, F.; Aberle, O.; Andrzejewski, J.; Audouin, L.; Bécares, V.; Bacak, M.; Balibrea-Correa, J.; Barbagallo, M.; Barros, S.; Bečvář, F.; Beinrucker, C.; Belloni, F.; Berthoumieux, E.; Billowes, J.; Bosnar, D.; Brugger, M.; Caamaño, M.; Calviño, F.; Calviani, M.; Cano-Ott, D.; Cardella, R.; Casanovas, A.; Castelluccio, D. M.; Cerutti, F.; Chen, Y. H.; Chiaveri, E.; Colonna, N.; Cortés-Giraldo, M. A.; Cortés, G.; Cosentino, L.; Damone, L. A.; Deo, K.; Diakaki, M.; Domingo-Pardo, C.; Dressler, R.; Dupont, E.; Durán, I.; Fernández-Domínguez, B.; Ferrari, A.; Ferreira, P.; Finocchiaro, P.; Frost, R. J. W.; Furman, V.; Ganesan, S.; García, A. R.; Gawlik, A.; Gheorghe, I.; Glodariu, T.; Gonçalves, I. F.; González, E.; Goverdovski, A.; Griesmayer, E.; Guerrero, C.; Göbel, K.; Harada, H.; Heftrich, T.; Heinitz, S.; Hernández-Prieto, A.; Heyse, J.; Jenkins, D. G.; Jericha, E.; Käppeler, F.; Kadi, Y.; Katabuchi, T.; Kavrigin, P.; Ketlerov, V.; Khryachkov, V.; Kimura, A.; Kivel, N.; Kokkoris, M.; Krtička, M.; Leal-Cidoncha, E.; Lederer, C.; Leeb, H.; Lerendegui, J.; Licata, M.; Lo Meo, S.; Lonsdale, S. J.; Losito, R.; Macina, D.; Marganiec, J.; Martínez, T.; Masi, A.; Massimi, C.; Mastinu, P.; Mastromarco, M.; Matteucci, F.; Maugeri, E. A.; Mazzone, A.; Mendoza, E.; Mengoni, A.; Milazzo, P. M.; Mingrone, F.; Mirea, M.; Montesano, S.; Musumarra, A.; Nolte, R.; Oprea, A.; Palomo-Pinto, F. R.; Paradela, C.; Patronis, N.; Pavlik, A.; Perkowski, J.; Porras, I.; Praena, J.; Quesada, J. M.; Rajeev, K.; Rauscher, T.; Reifarth, R.; Riego-Perez, A.; Robles, M.; Rout, P.; Radeck, D.; Rubbia, C.; Ryan, J. A.; Sabaté-Gilarte, M.; Saxena, A.; Schillebeeckx, P.; Schmidt, S.; Schumann, D.; Sedyshev, P.; Smith, A. G.; Stamatopoulos, A.; Suryanarayana, S. V.; Tagliente, G.; Tain, J. L.; Tarifeño-Saldivia, A.; Tarrío, D.; Tassan-Got, L.; Tsinganis, A.; Valenta, S.; Vannini, G.; Variale, V.; Vaz, P.; Ventura, A.; Vlachoudis, V.; Vlastou, R.; Wallner, A.; Warren, S.; Weigand, M.; Weiss, C.; Wolf, C.; Woods, P. J.; Wright, T.; Žugec, P.

2016-10-01

Nuclear data in general, and neutron-induced reaction cross sections in particular, are important for a wide variety of research fields. They play a key role in the safety and criticality assessment of nuclear technology, not only for existing power reactors but also for radiation dosimetry, medical applications, the transmutation of nuclear waste, accelerator-driven systems, fuel cycle investigations and future reactor systems as in Generation IV. Applications of nuclear data are also related to research fields as the study of nuclear level densities and stellar nucleosynthesis. Simulations and calculations of nuclear technology applications largely rely on evaluated nuclear data libraries. The evaluations in these libraries are based both on experimental data and theoretical models. Experimental nuclear reaction data are compiled on a worldwide basis by the international network of Nuclear Reaction Data Centres (NRDC) in the EXFOR database. The EXFOR database forms an important link between nuclear data measurements and the evaluated data libraries. CERN's neutron time-of-flight facility n_TOF has produced a considerable amount of experimental data since it has become fully operational with the start of the scientific measurement programme in 2001. While for a long period a single measurement station (EAR1) located at 185 m from the neutron production target was available, the construction of a second beam line at 20 m (EAR2) in 2014 has substantially increased the measurement capabilities of the facility. An outline of the experimental nuclear data activities at CERN's neutron time-of-flight facility n_TOF will be presented.

High duty factor plasma generator for CERN's Superconducting Proton Linac.

PubMed

Lettry, J; Kronberger, M; Scrivens, R; Chaudet, E; Faircloth, D; Favre, G; Geisser, J-M; Küchler, D; Mathot, S; Midttun, O; Paoluzzi, M; Schmitzer, C; Steyaert, D

2010-02-01

CERN's Linac4 is a 160 MeV linear accelerator currently under construction. It will inject negatively charged hydrogen ions into CERN's PS-Booster. Its ion source is a noncesiated rf driven H(-) volume source directly inspired from the one of DESY and is aimed to deliver pulses of 80 mA of H(-) during 0.4 ms at a 2 Hz repetition rate. The Superconducting Proton Linac (SPL) project is part of the luminosity upgrade of the Large Hadron Collider. It consists of an extension of Linac4 up to 5 GeV and is foreseen to deliver protons to a future 50 GeV synchrotron (PS2). For the SPL high power option (HP-SPL), the ion source would deliver pulses of 80 mA of H(-) during 1.2 ms and operate at a 50 Hz repetition rate. This significant upgrade motivates the design of the new water cooled plasma generator presented in this paper. Its engineering is based on the results of a finite element thermal study of the Linac4 H(-) plasma generator that identified critical components and thermal barriers. A cooling system is proposed which achieves the required heat dissipation and maintains the original functionality. Materials with higher thermal conductivity are selected and, wherever possible, thermal barriers resulting from low pressure contacts are removed by brazing metals on insulators. The AlN plasma chamber cooling circuit is inspired from the approach chosen for the cesiated high duty factor rf H(-) source operating at SNS.

Tape SCSI monitoring and encryption at CERN

NASA Astrophysics Data System (ADS)

Laskaridis, Stefanos; Bahyl, V.; Cano, E.; Leduc, J.; Murray, S.; Cancio, G.; Kruse, D.

2017-10-01

CERN currently manages the largest data archive in the HEP domain; over 180PB of custodial data is archived across 7 enterprise tape libraries containing more than 25,000 tapes and using over 100 tape drives. Archival storage at this scale requires a leading edge monitoring infrastructure that acquires live and lifelong metrics from the hardware in order to assess and proactively identify potential drive and media level issues. In addition, protecting the privacy of sensitive archival data is becoming increasingly important and with it the need for a scalable, compute-efficient and cost-effective solution for data encryption. In this paper, we first describe the implementation of acquiring tape medium and drive related metrics reported by the SCSI interface and its integration with our monitoring system. We then address the incorporation of tape drive real-time encryption with dedicated drive hardware into the CASTOR [1] hierarchical mass storage system.

34 CFR 300.11 - Day; business day; school day.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Day; business day; school day. 300.11 Section 300.11 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF...

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

Tires from space shuttle Endeavour's final flight are on display at the California Science Center's, California Experience gallery, Tuesday, Oct. 30, 2012, in Los Angeles. The grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion took place on Tuesday, Oct. 30, 2012. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

Novel apparatus and methods for performing remotely controlled particle-solid interaction experiments at CERN

NASA Astrophysics Data System (ADS)

Krause, H. F.; Deveney, E. F.; Jones, N. L.; Vane, C. R.; Datz, S.; Knudsen, H.; Grafström, P.; Schuch, R.

1997-04-01

Recent atomic physics studies involving ultrarelativistic Pb ions required solid target positioners, scintillators, and a sophisticated data acquisition and control system placed in a remote location at the CERN Super Proton Synchrotron near Geneva, Switzerland. The apparatus, installed in a high-radiation zone underground, had to (i) function for months, (ii) automatically respond to failures such as power outages and particle-induced computer upsets, and (iii) communicate with the outside world via a telephone line. The heart of the apparatus developed was an Apple Macintosh-based CAMAC system that answered the telephone and interpreted and executed remote control commands that (i) sensed and set targets, (ii) controlled voltages and discriminator levels for scintillators, (iii) modified data acquisition hardware logic, (iv) reported control information, and (v) automatically synchronized data acquisition to the CERN spill cycle via a modem signal and transmitted experimental data to a remote computer. No problems were experienced using intercontinental telephone connections at 1200 baud. Our successful "virtual laboratory" approach that uses off-the-shelf electronics is generally adaptable to more conventional bench-type experiments.

Chicago Ebola Response Network (CERN): A Citywide Cross-hospital Collaborative for Infectious Disease Preparedness.

PubMed

Lateef, Omar; Hota, Bala; Landon, Emily; Kociolek, Larry K; Morita, Julie; Black, Stephanie; Noskin, Gary; Kelleher, Michael; Curell, Krista; Galat, Amy; Ansell, David; Segreti, John; Weber, Stephen G

2015-11-15

The 2014-2015 Ebola virus disease (EVD) epidemic and international public health emergency has been referred to as a "black swan" event, or an event that is unlikely, hard to predict, and highly impactful once it occurs. The Chicago Ebola Response Network (CERN) was formed in response to EVD and is capable of receiving and managing new cases of EVD, while also laying the foundation for a public health network that can anticipate, manage, and prevent the next black swan public health event. By sharing expertise, risk, and resources among 4 major academic centers, Chicago created a sustainable network to respond to the latest in a series of public health emergencies. In this respect, CERN is a roadmap for how a region can prepare to respond to public health emergencies, thereby preventing negative impacts through planning and implementation. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

The 2015 Bioinformatics Open Source Conference (BOSC 2015)

PubMed Central

Harris, Nomi L.; Cock, Peter J. A.; Lapp, Hilmar

2016-01-01

The Bioinformatics Open Source Conference (BOSC) is organized by the Open Bioinformatics Foundation (OBF), a nonprofit group dedicated to promoting the practice and philosophy of open source software development and open science within the biological research community. Since its inception in 2000, BOSC has provided bioinformatics developers with a forum for communicating the results of their latest efforts to the wider research community. BOSC offers a focused environment for developers and users to interact and share ideas about standards; software development practices; practical techniques for solving bioinformatics problems; and approaches that promote open science and sharing of data, results, and software. BOSC is run as a two-day special interest group (SIG) before the annual Intelligent Systems in Molecular Biology (ISMB) conference. BOSC 2015 took place in Dublin, Ireland, and was attended by over 125 people, about half of whom were first-time attendees. Session topics included “Data Science;” “Standards and Interoperability;” “Open Science and Reproducibility;” “Translational Bioinformatics;” “Visualization;” and “Bioinformatics Open Source Project Updates”. In addition to two keynote talks and dozens of shorter talks chosen from submitted abstracts, BOSC 2015 included a panel, titled “Open Source, Open Door: Increasing Diversity in the Bioinformatics Open Source Community,” that provided an opportunity for open discussion about ways to increase the diversity of participants in BOSC in particular, and in open source bioinformatics in general. The complete program of BOSC 2015 is available online at http://www.open-bio.org/wiki/BOSC_2015_Schedule. PMID:26914653

Turning the rumor of May 11, 2011 earthquake prediction In Rome, Italy, into an information day on earthquake hazard

NASA Astrophysics Data System (ADS)

Amato, A.; Cultrera, G.; Margheriti, L.; Nostro, C.; Selvaggi, G.; INGVterremoti Team

2011-12-01

A devastating earthquake had been predicted for May 11, 2011 in Rome. This prediction was never released officially by anyone, but it grew up in the Internet and was amplified by media. It was erroneously ascribed to Raffaele Bendandi, an Italian self-taught natural scientist who studied planetary motions. Indeed, around May 11, 2011, a planetary alignment was really expected and this contributed to give credibility to the earthquake prediction among people. During the previous months, INGV was overwhelmed with requests for information about this supposed prediction by Roman inhabitants and tourists. Given the considerable mediatic impact of this expected earthquake, INGV decided to organize an Open Day in its headquarter in Rome for people who wanted to learn more about the Italian seismicity and the earthquake as natural phenomenon. The Open Day was preceded by a press conference two days before, in which we talked about this prediction, we presented the Open Day, and we had a scientific discussion with journalists about the earthquake prediction and more in general on the real problem of seismic risk in Italy. About 40 journalists from newspapers, local and national tv's, press agencies and web news attended the Press Conference and hundreds of articles appeared in the following days, advertising the 11 May Open Day. The INGV opened to the public all day long (9am - 9pm) with the following program: i) meetings with INGV researchers to discuss scientific issues; ii) visits to the seismic monitoring room, open 24h/7 all year; iii) guided tours through interactive exhibitions on earthquakes and Earth's deep structure; iv) lectures on general topics from the social impact of rumors to seismic risk reduction; v) 13 new videos on channel YouTube.com/INGVterremoti to explain the earthquake process and give updates on various aspects of seismic monitoring in Italy; vi) distribution of books and brochures. Surprisingly, more than 3000 visitors came to visit INGV

Prospective Nonrandomized Comparative Study of Laparoscopic Versus Open Surgical Staging for Endometrial Cancer in India.

PubMed

Ansar P P; Ayyappan S; Mahajan, Vikash

2018-06-01

Laparoscopic procedures to treat endometrial cancer are currently emerging. At present, we have evidence to do laparoscopic oncologic resections for endometrial cancer as proven by many prospective studies from abroad such as LAP2 by GOG. So, we have decided to assess the safety and feasibility of such a study in our population with the following as our primary objectives: (1) to study whether laparoscopy is better compared to open approach in terms of duration of hospital stay, perioperative morbidity and early recovery from surgical trauma and (2) to study whether the laparoscopic approach is noninferior to the open approach in terms of number of lymph nodes harvested in lymphadenectomy and rate of conversion to open surgery. We did a prospective nonrandomized comparative study of open versus laparoscopy approach for surgical staging of endometrial cancer from 16th May 2013 to 15th May 2015. To prove a significant difference in the hospital stay, we needed 29 patients in each arm. Thirty patients in each arm were enrolled for the study. The median duration of stay in the open arm was 7 days and in the laparoscopy arm it was 5 days. The advantage of 2 days in the laparoscopic arm was statistically significant ( P value 0.006). Forty percent of patients in the open arm had to stay in the hospital for more than 7 days whereas only 3% of patients in the laparoscopy arm required to stay for more than 7 days ( P value 0.001). This difference was statistically significant. There was no significant difference between the early complication rates between the two arms (20% in open vs. 13% in laparoscopy; P value 0.730). There was a conversion rate of 10% in laparoscopy. The median number of nodes harvested in open arm was 16.50 and in the laparoscopy arm, it was 13.50. The difference was not statistically significant ( P value 0.086). Laparoscopy approach for endometrial cancer staging is feasible in Indian patients and the short-term advantages are replicable with

Laparoscopic versus open resection for sigmoid diverticulitis.

PubMed

Abraha, Iosief; Binda, Gian A; Montedori, Alessandro; Arezzo, Alberto; Cirocchi, Roberto

2017-11-25

female. Inclusion criteria differed among studies. One trial included participants with Hinchey I characteristics as well as those who underwent Hartmann's procedure; the second trial included only participants with "a proven stage II/III disease according to the classification of Stock and Hansen"; the third trial considered for inclusion patients with "diverticular disease of sigmoid colon documented by colonoscopy and 2 episodes of uncomplicated diverticulitis, one at least being documented with CT scan, 1 episode of complicated diverticulitis, with a pericolic abscess (Hinchey stage I) or pelvic abscess (Hinchey stage II) requiring percutaneous drainage."We determined that two studies were at low risk of selection bias; two that reported considerable dropouts were at high risk of attrition bias; none reported blinding of outcome assessors (unclear detection bias); and all were exposed to performance bias owing to the nature of the intervention.Available low-quality evidence suggests that laparoscopic surgical resection may lead to little or no difference in mean hospital stay compared with open surgical resection (3 studies, 360 participants; MD -0.62 (days), 95% CI -2.49 to 1.25; I² = 0%).Low-quality evidence suggests that operating time was longer in the laparoscopic surgery group than in the open surgery group (3 studies, 360 participants; MD 49.28 (minutes), 95% CI 40.64 to 57.93; I² = 0%).We are uncertain whether laparoscopic surgery improves postoperative pain between day 1 and day 3 more effectively than open surgery. Low-quality evidence suggests that laparoscopic surgery may improve postoperative pain at the fourth postoperative day more effectively than open surgery (2 studies, 250 participants; MD = -0.65, 95% CI -1.04 to -0.25).Researchers reported quality of life differently across trials, hindering the possibility of meta-analysis. Low-quality evidence from one trial using the Short Form (SF)-36 questionnaire six weeks after surgery suggests that

Heminephroureterectomy for duplex kidney: laparoscopy versus open surgery.

PubMed

García-Aparicio, Luis; Krauel, Lucas; Tarrado, Xavier; Olivares, Marta; García-Nuñez, Bernardo; Lerena, Javier; Saura, Laura; Rovira, Jorge; Rodo, Joan

2010-04-01

To report our experience of laparoscopic heminephroureterectomy (Hnu) in pediatric patients with duplex anomalies, in comparison to open surgery. Retrospective review of data from patients who underwent Hnu from 2005 to 2008 was performed. The patients were divided into two groups: laparoscopic (LHnu) and open surgery (OHnu). Laparoscopic surgery was performed by transperitoneal approach in majority of cases. Open surgery was performed by retroperitoneal approach in all cases. Group LHnu: nine patients (8 females, 1 male) with median age of 14 months (range 3-205). Transperitoneal approach was performed in eight patients. Mean operative time was 182 min (CI 95% 146-217). No conversion to open surgery was necessary and there were no complications. Mean hospital stay was 2.44 days (CI 95% 1.37-3.52). Group OHnu: eight patients (3 females, 5 males) underwent nine heminephrectomies at median age of 6.9 months (range 1-12). Mean operating time was 152 min (CI 95% 121-183). There were no complications and mean hospital stay was 4.38 (CI 95% 2.59-6.16) days. Statistical analysis showed no statistically significant difference (P>0.05) in operating time between groups while mean hospital stay was significant (P=0.021). The laparoscopic approach is feasible, safe, reduces hospital stay, does not increase operating time and has better cosmetic results. We believe this should be the first option for heminephrectomy. Copyright © 2009 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

Long distance education for croatian nurses with open source software.

PubMed

Radenovic, Aleksandar; Kalauz, Sonja

2006-01-01

Croatian Nursing Informatics Association (CNIA) has been established as result of continuing work on promoting nursing informatics in Croatia. Main goals of CNIA are promoting nursing informatics and education of nurses about nursing informatics and using information technology in nursing process. CNIA in start of work is developed three courses from nursing informatics all designed with support of long distance education with open source software. Courses are: A - 'From Data to Wisdom', B - 'Introduction to Nursing Informatics' and C - 'Nursing Informatics I'. Courses A and B are obligatory for C course. Technology used to implement these online courses is based on the open source Learning Management System (LMS), Claroline, free online collaborative learning platform. Courses are divided in two modules/days. First module/day participants have classical approach to education and second day with E-learning from home. These courses represent first courses from nursing informatics' and first long distance education for nurses also.

Studies of effects of closed microbial ecology. Report of 180-day test period

NASA Technical Reports Server (NTRS)

Kenyon, A. J.

1972-01-01

Experiments were performed to determine the influence closed microbial ecologies have on modification or simplification of natural intestinal flora of ferrets in a closed environmental system. On the basis of previous tests in which certain species (Salmonella and Bacteroides) were decreased at 90 days of enclosure, a second trial was constructed for 180-day tests. In this trial there was little difference in the 8 major classes of intestinal flora between animals in the Open and Closed environmental groups except for the level of Lactobacillus. It is of extreme importance to note that when both Open and Closed groups contracted hemorrhagic gastritis, the interrelationship of this agent with other intestinal flora produced a more profound effect on animals from the Closed Group, particularly with reference to Lactobacillus levels.

Beyond Open Data: the importance of data standards and interoperability - Experiences from ECMWF's Open Data Week

NASA Astrophysics Data System (ADS)

Wagemann, Julia; Siemen, Stephan

2017-04-01

The European Centre for Medium-Range Weather Forecasts (ECMWF) has been providing an increasing amount of data to the public. One of the most widely used datasets include the global climate reanalyses (e.g. ERA-interim) and atmospheric composition data, which are available to the public free of charge. The centre is further operating, on behalf of the European Commission, two Copernicus Services, the Copernicus Atmosphere Monitoring Service (CAMS) and Climate Change Service (C3S), which are making up-to-date environmental information freely available for scientists, policy makers and businesses. However, to fully benefit from open data, large environmental datasets also have to be easily accessible in a standardised, machine-readable format. Traditional data centres, such as ECMWF, currently face challenges in providing interoperable standardised access to increasingly large and complex datasets for scientists and industry. Therefore, ECMWF put open data in the spotlight during a week of events in March 2017 exploring the potential of freely available weather- and climate-related data and to review technological solutions serving these data. Key events included a Workshop on Meteorological Operational Systems (MOS) and a two-day hackathon. The MOS workshop aimed at reviewing technologies and practices to ensure efficient (open) data processing and provision. The hackathon focused on exploring creative uses of open environmental data and to see how open data is beneficial for various industries. The presentation aims to give a review of the outcomes and conclusions of the Open Data Week at ECMWF. A specific focus will be set on the importance of data standards and web services to make open environmental data a success. The presentation overall examines the opportunities and challenges of open environmental data from a data provider's perspective.

Randomised controlled trial of laparoscopic versus open mesh repair for inguinal hernia: outcome and cost

PubMed Central

Wellwood, James; Sculpher, Mark J; Stoker, David; Nicholls, Graham J; Geddes, Cathy; Whitehead, Anne; Singh, Rameet; Spiegelhalter, David

1998-01-01

Objective: To compare tension-free open mesh hernioplasty under local anaesthetic with transabdominal preperitoneal laparoscopic hernia repair under general anaesthetic. Design: A randomised controlled trial of 403 patients with inguinal hernias. Setting: Two acute general hospitals in London between May 1995 and December 1996. Subjects: 400 patients with a diagnosis of groin hernia, 200 in each group. Main outcome measures: Time until discharge, postoperative pain, and complications; patients’ perceived health (SF-36), duration of convalescence, and patients’ satisfaction with surgery; and health service costs. Results: More patients in the open group (96%) than in the laparoscopic group (89%) were discharged on the same day as the operation (χ2=6.7; 1 df; P=0.01). Although pain scores were lower in the open group while the effect of the local anaesthetic persisted (proportional odds ratio at 2 hours 3.5 (2.3 to 5.1)), scores after open repair were significantly higher for each day of the first week (0.5 (0.3 to 0.7) on day 7) and during the second week (0.7 (0.5 to 0.9)). At 1 month there was a greater improvement (or less deterioration) in mean SF-36 scores over baseline in the laparoscopic group compared with the open group on seven of eight dimensions, reaching significance on five. For every activity considered the median time until return to normal was significantly shorter for the laparoscopic group. Patients randomised to laparoscopic repair were more satisfied with surgery at 1 month and 3 months after surgery. The mean cost per patient of laparoscopic repair was £335 (95% confidence interval £228 to £441) more than the cost of open repair. Conclusion: This study confirms that laparoscopic hernia repair has considerable short term clinical advantages after discharge compared with open mesh hernioplasty, although it was more expensive. Key messages In the 4 hours after surgery laparoscopic hernia repair with general anaesthesia causes more pain

Comparison of electromagnetic and hadronic models generated using Geant 4 with antiproton dose measured in CERN.

PubMed

Tavakoli, Mohammad Bagher; Reiazi, Reza; Mohammadi, Mohammad Mehdi; Jabbari, Keyvan

2015-01-01

After proposing the idea of antiproton cancer treatment in 1984 many experiments were launched to investigate different aspects of physical and radiobiological properties of antiproton, which came from its annihilation reactions. One of these experiments has been done at the European Organization for Nuclear Research known as CERN using the antiproton decelerator. The ultimate goal of this experiment was to assess the dosimetric and radiobiological properties of beams of antiprotons in order to estimate the suitability of antiprotons for radiotherapy. One difficulty on this way was the unavailability of antiproton beam in CERN for a long time, so the verification of Monte Carlo codes to simulate antiproton depth dose could be useful. Among available simulation codes, Geant4 provides acceptable flexibility and extensibility, which progressively lead to the development of novel Geant4 applications in research domains, especially modeling the biological effects of ionizing radiation at the sub-cellular scale. In this study, the depth dose corresponding to CERN antiproton beam energy by Geant4 recruiting all the standard physics lists currently available and benchmarked for other use cases were calculated. Overall, none of the standard physics lists was able to draw the antiproton percentage depth dose. Although, with some models our results were promising, the Bragg peak level remained as the point of concern for our study. It is concluded that the Bertini model with high precision neutron tracking (QGSP_BERT_HP) is the best to match the experimental data though it is also the slowest model to simulate events among the physics lists.

Cost comparison of laparoscopic colectomy versus open colectomy in colon cancer.

PubMed

Fitch, Kathryn; Bochner, Andrew; Keller, Deborah S

2017-07-01

Laparoscopic colectomy has been shown to be safe, oncologically comparable, and clinically beneficial over open colectomy for colon cancer, but utilization remains low. Objectives To evaluate the cost of laparoscopic colectomy vs open colectomy for colon cancer. The authors conducted a retrospective claims data analysis using the 2012 and 2013 Truven Health Analytics MarketScan Commercial Claims and Encounter Database. The denominator population consisted of individuals who had commercial insurance coverage in all months of 2012 and >1 month in 2013 and pharmacy coverage throughout eligibility. The study population included individuals aged 18-64 years who were identified with colon cancer in 2013 and underwent an elective inpatient open colectomy or laparoscopic colectomy between January and November 2013. The cost and re-admission rate of open vs laparoscopic colectomy were compared after risk, adjusting for comorbidities, demographics, and geographic region. During the study period, 1299 elective inpatient colon cancer colectomies were performed (open, n = 558; laparoscopic, n = 741). After risk adjustment, the laparoscopic vs open group was shown to have lower re-admission rates (6.61 and 10.93 per 100 cases, respectively, p = .0165), lower average re-admission costs ($1676 and $3151, respectively, p = .0309), and lower 30-day post-discharge healthcare utilization costs ($4842 and $7121, respectively, p = .0047). Average allowed cost for the combined inpatient and 30-day post-discharge period was lower for laparoscopic vs open colectomy cases ($36,395 and $44,226, respectively, p < .001). The cost of laparoscopic colectomy was found to be statistically significantly less than that of open colectomy in patients undergoing elective surgery for colon cancer.

Evaluation results of xTCA equipment for HEP experiments at CERN

NASA Astrophysics Data System (ADS)

Di Cosmo, M.; Bobillier, V.; Haas, S.; Joos, M.; Mico, S.; Vasey, F.; Vichoudis, P.

2013-12-01

The MicroTCA and AdvancedTCA industry standards are candidate modular electronic platforms for the upgrade of the current generation of high energy physics experiments. The PH-ESE group at CERN launched in 2011 the xTCA evaluation project with the aim of performing technical evaluations and eventually providing support for commercially available components. Different devices from different vendors have been acquired, evaluated and interoperability tests have been performed. This paper presents the test procedures and facilities that have been developed and focuses on the evaluation results including electrical, thermal and interoperability aspects.

Monitoring tools of COMPASS experiment at CERN

NASA Astrophysics Data System (ADS)

Bodlak, M.; Frolov, V.; Huber, S.; Jary, V.; Konorov, I.; Levit, D.; Novy, J.; Salac, R.; Tomsa, J.; Virius, M.

2015-12-01

This paper briefly introduces the data acquisition system of the COMPASS experiment and is mainly focused on the part that is responsible for the monitoring of the nodes in the whole newly developed data acquisition system of this experiment. The COMPASS is a high energy particle experiment with a fixed target located at the SPS of the CERN laboratory in Geneva, Switzerland. The hardware of the data acquisition system has been upgraded to use FPGA cards that are responsible for data multiplexing and event building. The software counterpart of the system includes several processes deployed in heterogenous network environment. There are two processes, namely Message Logger and Message Browser, taking care of monitoring. These tools handle messages generated by nodes in the system. While Message Logger collects and saves messages to the database, the Message Browser serves as a graphical interface over the database containing these messages. For better performance, certain database optimizations have been used. Lastly, results of performance tests are presented.

The CMS experiment at the CERN LHC

NASA Astrophysics Data System (ADS)

CMS Collaboration; Chatrchyan, S.; Hmayakyan, G.; Khachatryan, V.; Sirunyan, A. M.; Adam, W.; Bauer, T.; Bergauer, T.; Bergauer, H.; Dragicevic, M.; Erö, J.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Glaser, P.; Hartl, C.; Hoermann, N.; Hrubec, J.; Hänsel, S.; Jeitler, M.; Kastner, K.; Krammer, M.; Magrans de Abril, I.; Markytan, M.; Mikulec, I.; Neuherz, B.; Nöbauer, T.; Oberegger, M.; Padrta, M.; Pernicka, M.; Porth, P.; Rohringer, H.; Schmid, S.; Schreiner, T.; Stark, R.; Steininger, H.; Strauss, J.; Taurok, A.; Uhl, D.; Waltenberger, W.; Walzel, G.; Widl, E.; Wulz, C.-E.; Petrov, V.; Prosolovich, V.; Chekhovsky, V.; Dvornikov, O.; Emeliantchik, I.; Litomin, A.; Makarenko, V.; Marfin, I.; Mossolov, V.; Shumeiko, N.; Solin, A.; Stefanovitch, R.; Suarez Gonzalez, J.; Tikhonov, A.; Fedorov, A.; Korzhik, M.; Missevitch, O.; Zuyeuski, R.; Beaumont, W.; Cardaci, M.; DeLanghe, E.; DeWolf, E. A.; Delmeire, E.; Ochesanu, S.; Tasevsky, M.; Van Mechelen, P.; D'Hondt, J.; DeWeirdt, S.; Devroede, O.; Goorens, R.; Hannaert, S.; Heyninck, J.; Maes, J.; Mozer, M. U.; Tavernier, S.; Van Doninck, W.; Van Lancker, L.; Van Mulders, P.; Villella, I.; Wastiels, C.; Yu, C.; Bouhali, O.; Charaf, O.; Clerbaux, B.; DeHarenne, P.; DeLentdecker, G.; Dewulf, J. P.; Elgammal, S.; Gindroz, R.; Hammad, G. H.; Mahmoud, T.; Neukermans, L.; Pins, M.; Pins, R.; Rugovac, S.; Stefanescu, J.; Sundararajan, V.; Vander Velde, C.; Vanlaer, P.; Wickens, J.; Tytgat, M.; Assouak, S.; Bonnet, J. L.; Bruno, G.; Caudron, J.; DeCallatay, B.; DeFavereau DeJeneret, J.; DeVisscher, S.; Demin, P.; Favart, D.; Felix, C.; Florins, B.; Forton, E.; Giammanco, A.; Grégoire, G.; Jonckman, M.; Kcira, D.; Keutgen, T.; Lemaitre, V.; Michotte, D.; Militaru, O.; Ovyn, S.; Pierzchala, T.; Piotrzkowski, K.; Roberfroid, V.; Rouby, X.; Schul, N.; Van der Aa, O.; Beliy, N.; Daubie, E.; Herquet, P.; Alves, G.; Pol, M. E.; Souza, M. H. G.; Vaz, M.; DeJesus Damiao, D.; Oguri, V.; Santoro, A.; Sznajder, A.; DeMoraes Gregores, E.; Iope, R. L.; Novaes, S. F.; Tomei, T.; Anguelov, T.; Antchev, G.; Atanasov, I.; Damgov, J.; Darmenov, N.; Dimitrov, L.; Genchev, V.; Iaydjiev, P.; Marinov, A.; Piperov, S.; Stoykova, S.; Sultanov, G.; Trayanov, R.; Vankov, I.; Cheshkov, C.; Dimitrov, A.; Dyulendarova, M.; Glushkov, I.; Kozhuharov, V.; Litov, L.; Makariev, M.; Marinova, E.; Markov, S.; Mateev, M.; Nasteva, I.; Pavlov, B.; Petev, P.; Petkov, P.; Spassov, V.; Toteva, Z.; Velev, V.; Verguilov, V.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Jiang, C. H.; Liu, B.; Shen, X. Y.; Sun, H. S.; Tao, J.; Wang, J.; Yang, M.; Zhang, Z.; Zhao, W. R.; Zhuang, H. L.; Ban, Y.; Cai, J.; Ge, Y. C.; Liu, S.; Liu, H. T.; Liu, L.; Qian, S. J.; Wang, Q.; Xue, Z. H.; Yang, Z. C.; Ye, Y. L.; Ying, J.; Li, P. J.; Liao, J.; Xue, Z. L.; Yan, D. S.; Yuan, H.; Carrillo Montoya, C. A.; Sanabria, J. C.; Godinovic, N.; Puljak, I.; Soric, I.; Antunovic, Z.; Dzelalija, M.; Marasovic, K.; Brigljevic, V.; Kadija, K.; Morovic, S.; Fereos, R.; Nicolaou, C.; Papadakis, A.; Ptochos, F.; Razis, P. A.; Tsiakkouri, D.; Zinonos, Z.; Hektor, A.; Kadastik, M.; Kannike, K.; Lippmaa, E.; Müntel, M.; Raidal, M.; Rebane, L.; Aarnio, P. A.; Anttila, E.; Banzuzi, K.; Bulteau, P.; Czellar, S.; Eiden, N.; Eklund, C.; Engstrom, P.; Heikkinen, A.; Honkanen, A.; Härkönen, J.; Karimäki, V.; Katajisto, H. M.; Kinnunen, R.; Klem, J.; Kortesmaa, J.; Kotamäki, M.; Kuronen, A.; Lampén, T.; Lassila-Perini, K.; Lefébure, V.; Lehti, S.; Lindén, T.; Luukka, P. R.; Michal, S.; Moura Brigido, F.; Mäenpää, T.; Nyman, T.; Nystén, J.; Pietarinen, E.; Skog, K.; Tammi, K.; Tuominen, E.; Tuominiemi, J.; Ungaro, D.; Vanhala, T. P.; Wendland, L.; Williams, C.; Iskanius, M.; Korpela, A.; Polese, G.; Tuuva, T.; Bassompierre, G.; Bazan, A.; David, P. Y.; Ditta, J.; Drobychev, G.; Fouque, N.; Guillaud, J. P.; Hermel, V.; Karneyeu, A.; LeFlour, T.; Lieunard, S.; Maire, M.; Mendiburu, P.; Nedelec, P.; Peigneux, J. P.; Schneegans, M.; Sillou, D.; Vialle, J. P.; Anfreville, M.; Bard, J. P.; Besson, P.; Bougamont, E.; Boyer, M.; Bredy, P.; Chipaux, R.; Dejardin, M.; Denegri, D.; Descamps, J.; Fabbro, B.; Faure, J. L.; Ganjour, S.; Gentit, F. X.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Jeanney, C.; Kircher, F.; Lemaire, M. C.; Lemoigne, Y.; Levesy, B.; Locci, E.; Lottin, J. P.; Mandjavidze, I.; Mur, M.; Pansart, J. P.; Payn, A.; Rander, J.; Reymond, J. M.; Rolquin, J.; Rondeaux, F.; Rosowsky, A.; Rousse, J. Y. A.; Sun, Z. H.; Tartas, J.; Van Lysebetten, A.; Venault, P.; Verrecchia, P.; Anduze, M.; Badier, J.; Baffioni, S.; Bercher, M.; Bernet, C.; Berthon, U.; Bourotte, J.; Busata, A.; Busson, P.; Cerutti, M.; Chamont, D.; Charlot, C.; Collard, C.; Debraine, A.; Decotigny, D.; Dobrzynski, L.; Ferreira, O.; Geerebaert, Y.; Gilly, J.; Gregory, C.; Guevara Riveros, L.; Haguenauer, M.; Karar, A.; Koblitz, B.; Lecouturier, D.; Mathieu, A.; Milleret, G.; Miné, P.; Paganini, P.; Poilleux, P.; Pukhaeva, N.; Regnault, N.; Romanteau, T.; Semeniouk, I.; Sirois, Y.; Thiebaux, C.; Vanel, J. C.; Zabi, A.; Agram, J. L.; Albert, A.; Anckenmann, L.; Andrea, J.; Anstotz, F.; Bergdolt, A. M.; Berst, J. D.; Blaes, R.; Bloch, D.; Brom, J. M.; Cailleret, J.; Charles, F.; Christophel, E.; Claus, G.; Coffin, J.; Colledani, C.; Croix, J.; Dangelser, E.; Dick, N.; Didierjean, F.; Drouhin, F.; Dulinski, W.; Ernenwein, J. P.; Fang, R.; Fontaine, J. C.; Gaudiot, G.; Geist, W.; Gelé, D.; Goeltzenlichter, T.; Goerlach, U.; Graehling, P.; Gross, L.; Hu, C. Guo; Helleboid, J. M.; Henkes, T.; Hoffer, M.; Hoffmann, C.; Hosselet, J.; Houchu, L.; Hu, Y.; Huss, D.; Illinger, C.; Jeanneau, F.; Juillot, P.; Kachelhoffer, T.; Kapp, M. R.; Kettunen, H.; Lakehal Ayat, L.; LeBihan, A. C.; Lounis, A.; Maazouzi, C.; Mack, V.; Majewski, P.; Mangeol, D.; Michel, J.; Moreau, S.; Olivetto, C.; Pallarès, A.; Patois, Y.; Pralavorio, P.; Racca, C.; Riahi, Y.; Ripp-Baudot, I.; Schmitt, P.; Schunck, J. P.; Schuster, G.; Schwaller, B.; Sigward, M. H.; Sohler, J. L.; Speck, J.; Strub, R.; Todorov, T.; Turchetta, R.; Van Hove, P.; Vintache, D.; Zghiche, A.; Ageron, M.; Augustin, J. E.; Baty, C.; Baulieu, G.; Bedjidian, M.; Blaha, J.; Bonnevaux, A.; Boudoul, G.; Brunet, P.; Chabanat, E.; Chabert, E. C.; Chierici, R.; Chorowicz, V.; Combaret, C.; Contardo, D.; Della Negra, R.; Depasse, P.; Drapier, O.; Dupanloup, M.; Dupasquier, T.; El Mamouni, H.; Estre, N.; Fay, J.; Gascon, S.; Giraud, N.; Girerd, C.; Guillot, G.; Haroutunian, R.; Ille, B.; Lethuillier, M.; Lumb, N.; Martin, C.; Mathez, H.; Maurelli, G.; Muanza, S.; Pangaud, P.; Perries, S.; Ravat, O.; Schibler, E.; Schirra, F.; Smadja, G.; Tissot, S.; Trocme, B.; Vanzetto, S.; Walder, J. P.; Bagaturia, Y.; Mjavia, D.; Mzhavia, A.; Tsamalaidze, Z.; Roinishvili, V.; Adolphi, R.; Anagnostou, G.; Brauer, R.; Braunschweig, W.; Esser, H.; Feld, L.; Karpinski, W.; Khomich, A.; Klein, K.; Kukulies, C.; Lübelsmeyer, K.; Olzem, J.; Ostaptchouk, A.; Pandoulas, D.; Pierschel, G.; Raupach, F.; Schael, S.; Schultz von Dratzig, A.; Schwering, G.; Siedling, R.; Thomas, M.; Weber, M.; Wittmer, B.; Wlochal, M.; Adamczyk, F.; Adolf, A.; Altenhöfer, G.; Bechstein, S.; Bethke, S.; Biallass, P.; Biebel, O.; Bontenackels, M.; Bosseler, K.; Böhm, A.; Erdmann, M.; Faissner, H.; Fehr, B.; Fesefeldt, H.; Fetchenhauer, G.; Frangenheim, J.; Frohn, J. H.; Grooten, J.; Hebbeker, T.; Hermann, S.; Hermens, E.; Hilgers, G.; Hoepfner, K.; Hof, C.; Jacobi, E.; Kappler, S.; Kirsch, M.; Kreuzer, P.; Kupper, R.; Lampe, H. R.; Lanske, D.; Mameghani, R.; Meyer, A.; Meyer, S.; Moers, T.; Müller, E.; Pahlke, R.; Philipps, B.; Rein, D.; Reithler, H.; Reuter, W.; Rütten, P.; Schulz, S.; Schwarthoff, H.; Sobek, W.; Sowa, M.; Stapelberg, T.; Szczesny, H.; Teykal, H.; Teyssier, D.; Tomme, H.; Tomme, W.; Tonutti, M.; Tsigenov, O.; Tutas, J.; Vandenhirtz, J.; Wagner, H.; Wegner, M.; Zeidler, C.; Beissel, F.; Davids, M.; Duda, M.; Flügge, G.; Giffels, M.; Hermanns, T.; Heydhausen, D.; Kalinin, S.; Kasselmann, S.; Kaussen, G.; Kress, T.; Linn, A.; Nowack, A.; Perchalla, L.; Poettgens, M.; Pooth, O.; Sauerland, P.; Stahl, A.; Tornier, D.; Zoeller, M. H.; Behrens, U.; Borras, K.; Flossdorf, A.; Hatton, D.; Hegner, B.; Kasemann, M.; Mankel, R.; Meyer, A.; Mnich, J.; Rosemann, C.; Youngman, C.; Zeuner, W. D.; Bechtel, F.; Buhmann, P.; Butz, E.; Flucke, G.; Hamdorf, R. H.; Holm, U.; Klanner, R.; Pein, U.; Schirm, N.; Schleper, P.; Steinbrück, G.; Van Staa, R.; Wolf, R.; Atz, B.; Barvich, T.; Blüm, P.; Boegelspacher, F.; Bol, H.; Chen, Z. Y.; Chowdhury, S.; DeBoer, W.; Dehm, P.; Dirkes, G.; Fahrer, M.; Felzmann, U.; Frey, M.; Furgeri, A.; Gregoriev, E.; Hartmann, F.; Hauler, F.; Heier, S.; Kärcher, K.; Ledermann, B.; Mueller, S.; Müller, Th; Neuberger, D.; Piasecki, C.; Quast, G.; Rabbertz, K.; Sabellek, A.; Scheurer, A.; Schilling, F. P.; Simonis, H. J.; Skiba, A.; Steck, P.; Theel, A.; Thümmel, W. H.; Trunov, A.; Vest, A.; Weiler, T.; Weiser, C.; Weseler, S.; Zhukov, V.; Barone, M.; Daskalakis, G.; Dimitriou, N.; Fanourakis, G.; Filippidis, C.; Geralis, T.; Kalfas, C.; Karafasoulis, K.; Koimas, A.; Kyriakis, A.; Kyriazopoulou, S.; Loukas, D.; Markou, A.; Markou, C.; Mastroyiannopoulos, N.; Mavrommatis, C.; Mousa, J.; Papadakis, I.; Petrakou, E.; Siotis, I.; Theofilatos, K.; Tzamarias, S.; Vayaki, A.; Vermisoglou, G.; Zachariadou, A.; Gouskos, L.; Karapostoli, G.; Katsas, P.; Panagiotou, A.; Papadimitropoulos, C.; Aslanoglou, X.; Evangelou, I.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Triantis, F. A.; Bencze, G.; Boldizsar, L.; Debreczeni, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Kovesarki, P.; Laszlo, A.; Odor, G.; Patay, G.; Sikler, F.; Veres, G.; Vesztergombi, G.; Zalan, P.; Fenyvesi, A.; Imrek, J.; Molnar, J.; Novak, D.; Palinkas, J.; Szekely, G.; Beni, N.; Kapusi, A.; Marian, G.; Radics, B.; Raics, P.; Szabo, Z.; Szillasi, Z.; Trocsanyi, Z. L.; Zilizi, G.; Bawa, H. S.; Beri, S. B.; Bhandari, V.; Bhatnagar, V.; Kaur, M.; Kohli, J. M.; Kumar, A.; Singh, B.; Singh, J. B.; Arora, S.; Bhattacharya, S.; Chatterji, S.; Chauhan, S.; Choudhary, B. C.; Gupta, P.; Jha, M.; Ranjan, K.; Shivpuri, R. K.; Srivastava, A. K.; Choudhury, R. K.; Dutta, D.; Ghodgaonkar, M.; Kailas, S.; Kataria, S. K.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, Sunanda; Bose, S.; Chendvankar, S.; Deshpande, P. V.; Guchait, M.; Gurtu, A.; Maity, M.; Majumder, G.; Mazumdar, K.; Nayak, A.; Patil, M. R.; Sharma, S.; Sudhakar, K.; Acharya, B. S.; Banerjee, Sudeshna; Bheesette, S.; Dugad, S.; Kalmani, S. D.; Lakkireddi, V. R.; Mondal, N. K.; Panyam, N.; Verma, P.; Arfaei, H.; Hashemi, M.; Najafabadi, M. Mohammadi; Moshaii, A.; Paktinat Mehdiabadi, S.; Felcini, M.; Grunewald, M.; Abadjiev, K.; Abbrescia, M.; Barbone, L.; Cariola, P.; Chiumarulo, F.; Clemente, A.; Colaleo, A.; Creanza, D.; DeFilippis, N.; DePalma, M.; DeRobertis, G.; Donvito, G.; Ferorelli, R.; Fiore, L.; Franco, M.; Giordano, D.; Guida, R.; Iaselli, G.; Lacalamita, N.; Loddo, F.; Maggi, G.; Maggi, M.; Manna, N.; Marangelli, B.; Mennea, M. S.; My, S.; Natali, S.; Nuzzo, S.; Papagni, G.; Pinto, C.; Pompili, A.; Pugliese, G.; Ranieri, A.; Romano, F.; Roselli, G.; Sala, G.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Trentadue, R.; Tupputi, S.; Zito, G.; Abbiendi, G.; Bacchi, W.; Battilana, C.; Benvenuti, A. C.; Boldini, M.; Bonacorsi, D.; Braibant-Giacomelli, S.; Cafaro, V. D.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Ciocca, C.; Codispoti, G.; Cuffiani, M.; D'Antone, I.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Finelli, S.; Giacomelli, P.; Giordano, V.; Giunta, M.; Grandi, C.; Guerzoni, M.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Odorici, F.; Paolucci, A.; Pellegrini, G.; Perrotta, A.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Torromeo, G.; Travaglini, R.; Veronese, G. P.; Albergo, S.; Chiorboli, M.; Costa, S.; Galanti, M.; Gatto Rotondo, G.; Giudice, N.; Guardone, N.; Noto, F.; Potenza, R.; Saizu, M. A.; Salemi, G.; Sutera, C.; Tricomi, A.; Tuve, C.; Bellucci, L.; Brianzi, M.; Broccolo, G.; Catacchini, E.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Frosali, S.; Genta, C.; Landi, G.; Lenzi, P.; Macchiolo, A.; Maletta, F.; Manolescu, F.; Marchettini, C.; Masetti, L.; Mersi, S.; Meschini, M.; Minelli, C.; Paoletti, S.; Parrini, G.; Scarlini, E.; Sguazzoni, G.; Benussi, L.; Bertani, M.; Bianco, S.; Caponero, M.; Colonna, D.; Daniello, L.; Fabbri, F.; Felli, F.; Giardoni, M.; La Monaca, A.; Ortenzi, B.; Pallotta, M.; Paolozzi, A.; Paris, C.; Passamonti, L.; Pierluigi, D.; Ponzio, B.; Pucci, C.; Russo, A.; Saviano, G.; Fabbricatore, P.; Farinon, S.; Greco, M.; Musenich, R.; Badoer, S.; Berti, L.; Biasotto, M.; Fantinel, S.; Frizziero, E.; Gastaldi, U.; Gulmini, M.; Lelli, F.; Maron, G.; Squizzato, S.; Toniolo, N.; Traldi, S.; Banfi, S.; Bertoni, R.; Bonesini, M.; Carbone, L.; Cerati, G. B.; Chignoli, F.; D'Angelo, P.; DeMin, A.; Dini, P.; Farina, F. M.; Ferri, F.; Govoni, P.; Magni, S.; Malberti, M.; Malvezzi, S.; Mazza, R.; Menasce, D.; Miccio, V.; Moroni, L.; Negri, P.; Paganoni, M.; Pedrini, D.; Pullia, A.; Ragazzi, S.; Redaelli, N.; Rovere, M.; Sala, L.; Sala, S.; Salerno, R.; Tabarelli de Fatis, T.; Tancini, V.; Taroni, S.; Boiano, A.; Cassese, F.; Cassese, C.; Cimmino, A.; D'Aquino, B.; Lista, L.; Lomidze, D.; Noli, P.; Paolucci, P.; Passeggio, G.; Piccolo, D.; Roscilli, L.; Sciacca, C.; Vanzanella, A.; Azzi, P.; Bacchetta, N.; Barcellan, L.; Bellato, M.; Benettoni, M.; Bisello, D.; Borsato, E.; Candelori, A.; Carlin, R.; Castellani, L.; Checchia, P.; Ciano, L.; Colombo, A.; Conti, E.; Da Rold, M.; Dal Corso, F.; DeGiorgi, M.; DeMattia, M.; Dorigo, T.; Dosselli, U.; Fanin, C.; Galet, G.; Gasparini, F.; Gasparini, U.; Giraldo, A.; Giubilato, P.; Gonella, F.; Gresele, A.; Griggio, A.; Guaita, P.; Kaminskiy, A.; Karaevskii, S.; Khomenkov, V.; Kostylev, D.; Lacaprara, S.; Lazzizzera, I.; Lippi, I.; Loreti, M.; Margoni, M.; Martinelli, R.; Mattiazzo, S.; Mazzucato, M.; Meneguzzo, A. T.; Modenese, L.; Montecassiano, F.; Neviani, A.; Nigro, M.; Paccagnella, A.; Pantano, D.; Parenti, A.; Passaseo, M.; Pedrotta, R.; Pegoraro, M.; Rampazzo, G.; Reznikov, S.; Ronchese, P.; Sancho Daponte, A.; Sartori, P.; Stavitskiy, I.; Tessaro, M.; Torassa, E.; Triossi, A.; Vanini, S.; Ventura, S.; Ventura, L.; Verlato, M.; Zago, M.; Zatti, F.; Zotto, P.; Zumerle, G.; Baesso, P.; Belli, G.; Berzano, U.; Bricola, S.; Grelli, A.; Musitelli, G.; Nardò, R.; Necchi, M. M.; Pagano, D.; Ratti, S. P.; Riccardi, C.; Torre, P.; Vicini, A.; Vitulo, P.; Viviani, C.; Aisa, D.; Aisa, S.; Ambroglini, F.; Angarano, M. M.; Babucci, E.; Benedetti, D.; Biasini, M.; Bilei, G. M.; Bizzaglia, S.; Brunetti, M. T.; Caponeri, B.; Checcucci, B.; Covarelli, R.; Dinu, N.; Fanò, L.; Farnesini, L.; Giorgi, M.; Lariccia, P.; Mantovani, G.; Moscatelli, F.; Passeri, D.; Piluso, A.; Placidi, P.; Postolache, V.; Santinelli, R.; Santocchia, A.; Servoli, L.; Spiga, D.; Azzurri, P.; Bagliesi, G.; Balestri, G.; Basti, A.; Bellazzini, R.; Benucci, L.; Bernardini, J.; Berretta, L.; Bianucci, S.; Boccali, T.; Bocci, A.; Borrello, L.; Bosi, F.; Bracci, F.; Brez, A.; Calzolari, F.; Castaldi, R.; Cazzola, U.; Ceccanti, M.; Cecchi, R.; Cerri, C.; Cucoanes, A. S.; Dell'Orso, R.; Dobur, D.; Dutta, S.; Fiori, F.; Foà, L.; Gaggelli, A.; Gennai, S.; Giassi, A.; Giusti, S.; Kartashov, D.; Kraan, A.; Latronico, L.; Ligabue, F.; Linari, S.; Lomtadze, T.; Lungu, G. A.; Magazzu, G.; Mammini, P.; Mariani, F.; Martinelli, G.; Massa, M.; Messineo, A.; Moggi, A.; Palla, F.; Palmonari, F.; Petragnani, G.; Petrucciani, G.; Profeti, A.; Raffaelli, F.; Rizzi, D.; Sanguinetti, G.; Sarkar, S.; Segneri, G.; Sentenac, D.; Serban, A. T.; Slav, A.; Spagnolo, P.; Spandre, G.; Tenchini, R.; Tolaini, S.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Vos, M.; Zaccarelli, L.; Baccaro, S.; Barone, L.; Bartoloni, A.; Borgia, B.; Capradossi, G.; Cavallari, F.; Cecilia, A.; D'Angelo, D.; Dafinei, I.; DelRe, D.; Di Marco, E.; Diemoz, M.; Ferrara, G.; Gargiulo, C.; Guerra, S.; Iannone, M.; Longo, E.; Montecchi, M.; Nuccetelli, M.; Organtini, G.; Palma, A.; Paramatti, R.; Pellegrino, F.; Rahatlou, S.; Rovelli, C.; Safai Tehrani, F.; Zullo, A.; Alampi, G.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Benotto, F.; Biino, C.; Bolognesi, S.; Borgia, M. A.; Botta, C.; Brasolin, A.; Cartiglia, N.; Castello, R.; Cerminara, G.; Cirio, R.; Cordero, M.; Costa, M.; Dattola, D.; Daudo, F.; Dellacasa, G.; Demaria, N.; Dughera, G.; Dumitrache, F.; Farano, R.; Ferrero, G.; Filoni, E.; Kostyleva, G.; Larsen, H. E.; Mariotti, C.; Marone, M.; Maselli, S.; Menichetti, E.; Mereu, P.; Migliore, E.; Mila, G.; Monaco, V.; Musich, M.; Nervo, M.; Obertino, M. M.; Panero, R.; Parussa, A.; Pastrone, N.; Peroni, C.; Petrillo, G.; Romero, A.; Ruspa, M.; Sacchi, R.; Scalise, M.; Solano, A.; Staiano, A.; Trapani, P. P.; Trocino, D.; Vaniev, V.; Vilela Pereira, A.; Zampieri, A.; Belforte, S.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; Kavka, C.; Penzo, A.; Kim, Y. E.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, J. C.; Kong, D. J.; Ro, S. R.; Son, D. C.; Park, S. Y.; Kim, Y. J.; Kim, J. Y.; Lim, I. T.; Pac, M. Y.; Lee, S. J.; Jung, S. Y.; Rhee, J. T.; Ahn, S. H.; Hong, B. S.; Jeng, Y. K.; Kang, M. H.; Kim, H. C.; Kim, J. H.; Kim, T. J.; Lee, K. S.; Lim, J. K.; Moon, D. H.; Park, I. C.; Park, S. K.; Ryu, M. S.; Sim, K.-S.; Son, K. J.; Hong, S. J.; Choi, Y. I.; Castilla Valdez, H.; Sanchez Hernandez, A.; Carrillo Moreno, S.; Morelos Pineda, A.; Aerts, A.; Van der Stok, P.; Weffers, H.; Allfrey, P.; Gray, R. N. C.; Hashimoto, M.; Krofcheck, D.; Bell, A. J.; Bernardino Rodrigues, N.; Butler, P. H.; Churchwell, S.; Knegjens, R.; Whitehead, S.; Williams, J. C.; Aftab, Z.; Ahmad, U.; Ahmed, I.; Ahmed, W.; Asghar, M. I.; Asghar, S.; Dad, G.; Hafeez, M.; Hoorani, H. R.; Hussain, I.; Hussain, N.; Iftikhar, M.; Khan, M. S.; Mehmood, K.; Osman, A.; Shahzad, H.; Zafar, A. R.; Ali, A.; Bashir, A.; Jan, A. M.; Kamal, A.; Khan, F.; Saeed, M.; Tanwir, S.; Zafar, M. A.; Blocki, J.; Cyz, A.; Gladysz-Dziadus, E.; Mikocki, S.; Rybczynski, M.; Turnau, J.; Wlodarczyk, Z.; Zychowski, P.; Bunkowski, K.; Cwiok, M.; Czyrkowski, H.; Dabrowski, R.; Dominik, W.; Doroba, K.; Kalinowski, A.; Kierzkowski, K.; Konecki, M.; Krolikowski, J.; Kudla, I. M.; Pietrusinski, M.; Pozniak, K.; Zabolotny, W.; Zych, P.; Gokieli, R.; Goscilo, L.; Górski, M.; Nawrocki, K.; Traczyk, P.; Wrochna, G.; Zalewski, P.; Pozniak, K. T.; Romaniuk, R.; Zabolotny, W. M.; Alemany-Fernandez, R.; Almeida, C.; Almeida, N.; Araujo Vila Verde, A. S.; Barata Monteiro, T.; Bluj, M.; Da Mota Silva, S.; Tinoco Mendes, A. David; Freitas Ferreira, M.; Gallinaro, M.; Husejko, M.; Jain, A.; Kazana, M.; Musella, P.; Nobrega, R.; Rasteiro Da Silva, J.; Ribeiro, P. Q.; Santos, M.; Silva, P.; Silva, S.; Teixeira, I.; Teixeira, J. P.; Varela, J.; Varner, G.; Vaz Cardoso, N.; Altsybeev, I.; Babich, K.; Belkov, A.; Belotelov, I.; Bunin, P.; Chesnevskaya, S.; Elsha, V.; Ershov, Y.; Filozova, I.; Finger, M.; Finger, M., Jr.; Golunov, A.; Golutvin, I.; Gorbounov, N.; Gramenitski, I.; Kalagin, V.; Kamenev, A.; Karjavin, V.; Khabarov, S.; Khabarov, V.; Kiryushin, Y.; Konoplyanikov, V.; Korenkov, V.; Kozlov, G.; Kurenkov, A.; Lanev, A.; Lysiakov, V.; Malakhov, A.; Melnitchenko, I.; Mitsyn, V. V.; Moisenz, K.; Moisenz, P.; Movchan, S.; Nikonov, E.; Oleynik, D.; Palichik, V.; Perelygin, V.; Petrosyan, A.; Rogalev, E.; Samsonov, V.; Savina, M.; Semenov, R.; Sergeev, S.; Shmatov, S.; Shulha, S.; Smirnov, V.; Smolin, D.; Tcheremoukhine, A.; Teryaev, O.; Tikhonenko, E.; Urkinbaev, A.; Vasil'ev, S.; Vishnevskiy, A.; Volodko, A.; Zamiatin, N.; Zarubin, A.; Zarubin, P.; Zubarev, E.; Bondar, N.; Gavrikov, Y.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Kozlov, V.; Lebedev, V.; Makarenkov, G.; Moroz, F.; Neustroev, P.; Obrant, G.; Orishchin, E.; Petrunin, A.; Shcheglov, Y.; Shchetkovskiy, A.; Sknar, V.; Skorobogatov, V.; Smirnov, I.; Sulimov, V.; Tarakanov, V.; Uvarov, L.; Vavilov, S.; Velichko, G.; Volkov, S.; Vorobyev, A.; Chmelev, D.; Druzhkin, D.; Ivanov, A.; Kudinov, V.; Logatchev, O.; Onishchenko, S.; Orlov, A.; Sakharov, V.; Smetannikov, V.; Tikhomirov, A.; Zavodthikov, S.; Andreev, Yu; Anisimov, A.; Duk, V.; Gninenko, S.; Golubev, N.; Gorbunov, D.; Kirsanov, M.; Krasnikov, N.; Matveev, V.; Pashenkov, A.; Pastsyak, A.; Postoev, V. E.; Sadovski, A.; Skassyrskaia, A.; Solovey, Alexander; Solovey, Anatoly; Soloviev, D.; Toropin, A.; Troitsky, S.; Alekhin, A.; Baldov, A.; Epshteyn, V.; Gavrilov, V.; Ilina, N.; Kaftanov, V.; Karpishin, V.; Kiselevich, I.; Kolosov, V.; Kossov, M.; Krokhotin, A.; Kuleshov, S.; Oulianov, A.; Pozdnyakov, A.; Safronov, G.; Semenov, S.; Stepanov, N.; Stolin, V.; Vlasov, E.; Zaytsev, V.; Boos, E.; Dubinin, M.; Dudko, L.; Ershov, A.; Eyyubova, G.; Gribushin, A.; Ilyin, V.; Klyukhin, V.; Kodolova, O.; Kruglov, N. A.; Kryukov, A.; Lokhtin, I.; Malinina, L.; Mikhaylin, V.; Petrushanko, S.; Sarycheva, L.; Savrin, V.; Shamardin, L.; Sherstnev, A.; Snigirev, A.; Teplov, K.; Vardanyan, I.; Fomenko, A. M.; Konovalova, N.; Kozlov, V.; Lebedev, A. I.; Lvova, N.; Rusakov, S. V.; Terkulov, A.; Abramov, V.; Akimenko, S.; Artamonov, A.; Ashimova, A.; Azhgirey, I.; Bitioukov, S.; Chikilev, O.; Datsko, K.; Filine, A.; Godizov, A.; Goncharov, P.; Grishin, V.; Inyakin, A.; Kachanov, V.; Kalinin, A.; Khmelnikov, A.; Konstantinov, D.; Korablev, A.; Krychkine, V.; Krinitsyn, A.; Levine, A.; Lobov, I.; Lukanin, V.; Mel'nik, Y.; Molchanov, V.; Petrov, V.; Petukhov, V.; Pikalov, V.; Ryazanov, A.; Ryutin, R.; Shelikhov, V.; Skvortsov, V.; Slabospitsky, S.; Sobol, A.; Sytine, A.; Talov, V.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Zelepoukine, S.; Lukyanov, V.; Mamaeva, G.; Prilutskaya, Z.; Rumyantsev, I.; Sokha, S.; Tataurschikov, S.; Vasilyev, I.; Adzic, P.; Anicin, I.; Djordjevic, M.; Jovanovic, D.; Maletic, D.; Puzovic, J.; Smiljkovic, N.; Aguayo Navarrete, E.; Aguilar-Benitez, M.; Ahijado Munoz, J.; Alarcon Vega, J. M.; Alberdi, J.; Alcaraz Maestre, J.; Aldaya Martin, M.; Arce, P.; Barcala, J. M.; Berdugo, J.; Blanco Ramos, C. L.; Burgos Lazaro, C.; Caballero Bejar, J.; Calvo, E.; Cerrada, M.; Chamizo Llatas, M.; Chercoles Catalán, J. J.; Colino, N.; Daniel, M.; DeLa Cruz, B.; Delgado Peris, A.; Fernandez Bedoya, C.; Ferrando, A.; Fouz, M. C.; Francia Ferrero, D.; Garcia Romero, J.; Garcia-Abia, P.; Gonzalez Lopez, O.; Hernandez, J. M.; Josa, M. I.; Marin, J.; Merino, G.; Molinero, A.; Navarrete, J. J.; Oller, J. C.; Puerta Pelayo, J.; Puras Sanchez, J. C.; Ramirez, J.; Romero, L.; Villanueva Munoz, C.; Willmott, C.; Yuste, C.; Albajar, C.; de Trocóniz, J. F.; Jimenez, I.; Macias, R.; Teixeira, R. F.; Cuevas, J.; Fernández Menéndez, J.; Gonzalez Caballero, I.; Lopez-Garcia, J.; Naves Sordo, H.; Vizan Garcia, J. M.; Cabrillo, I. J.; Calderon, A.; Cano Fernandez, D.; Diaz Merino, I.; Duarte Campderros, J.; Fernandez, M.; Fernandez Menendez, J.; Figueroa, C.; Garcia Moral, L. A.; Gomez, G.; Gomez Casademunt, F.; Gonzalez Sanchez, J.; Gonzalez Suarez, R.; Jorda, C.; Lobelle Pardo, P.; Lopez Garcia, A.; Lopez Virto, A.; Marco, J.; Marco, R.; Martinez Rivero, C.; Martinez Ruiz del Arbol, P.; Matorras, F.; Orviz Fernandez, P.; Patino Revuelta, A.; Rodrigo, T.; Rodriguez Gonzalez, D.; Ruiz Jimeno, A.; Scodellaro, L.; Sobron Sanudo, M.; Vila, I.; Vilar Cortabitarte, R.; Barbero, M.; Goldin, D.; Henrich, B.; Tauscher, L.; Vlachos, S.; Wadhwa, M.; Abbaneo, D.; Abbas, S. M.; Ahmed, I.; Akhtar, S.; Akhtar, M. I.; Albert, E.; Alidra, M.; Ashby, S.; Aspell, P.; Auffray, E.; Baillon, P.; Ball, A.; Bally, S. L.; Bangert, N.; Barillère, R.; Barney, D.; Beauceron, S.; Beaudette, F.; Benelli, G.; Benetta, R.; Benichou, J. L.; Bialas, W.; Bjorkebo, A.; Blechschmidt, D.; Bloch, C.; Bloch, P.; Bonacini, S.; Bos, J.; Bosteels, M.; Boyer, V.; Branson, A.; Breuker, H.; Bruneliere, R.; Buchmuller, O.; Campi, D.; Camporesi, T.; Caner, A.; Cano, E.; Carrone, E.; Cattai, A.; Chatelain, J. P.; Chauvey, M.; Christiansen, T.; Ciganek, M.; Cittolin, S.; Cogan, J.; Conde Garcia, A.; Cornet, H.; Corrin, E.; Corvo, M.; Cucciarelli, S.; Curé, B.; D'Enterria, D.; DeRoeck, A.; de Visser, T.; Delaere, C.; Delattre, M.; Deldicque, C.; Delikaris, D.; Deyrail, D.; Di Vincenzo, S.; Domeniconi, A.; Dos Santos, S.; Duthion, G.; Edera, L. M.; Elliott-Peisert, A.; Eppard, M.; Fanzago, F.; Favre, M.; Foeth, H.; Folch, R.; Frank, N.; Fratianni, S.; Freire, M. A.; Frey, A.; Fucci, A.; Funk, W.; Gaddi, A.; Gagliardi, F.; Gastal, M.; Gateau, M.; Gayde, J. C.; Gerwig, H.; Ghezzi, A.; Gigi, D.; Gill, K.; Giolo-Nicollerat, A. S.; Girod, J. P.; Glege, F.; Glessing, W.; Gomez-Reino Garrido, R.; Goudard, R.; Grabit, R.; Grillet, J. P.; Gutierrez Llamas, P.; Gutierrez Mlot, E.; Gutleber, J.; Hall-wilton, R.; Hammarstrom, R.; Hansen, M.; Harvey, J.; Hervé, A.; Hill, J.; Hoffmann, H. F.; Holzner, A.; Honma, A.; Hufnagel, D.; Huhtinen, M.; Ilie, S. D.; Innocente, V.; Jank, W.; Janot, P.; Jarron, P.; Jeanrenaud, M.; Jouvel, P.; Kerkach, R.; Kloukinas, K.; Kottelat, L. J.; Labbé, J. C.; Lacroix, D.; Lagrue, X.; Lasseur, C.; Laure, E.; Laurens, J. F.; Lazeyras, P.; LeGoff, J. M.; Lebeau, M.; Lecoq, P.; Lemeilleur, F.; Lenzi, M.; Leonardo, N.; Leonidopoulos, C.; Letheren, M.; Liendl, M.; Limia-Conde, F.; Linssen, L.; Ljuslin, C.; Lofstedt, B.; Loos, R.; Lopez Perez, J. A.; Lourenco, C.; Lyonnet, A.; Machard, A.; Mackenzie, R.; Magini, N.; Maire, G.; Malgeri, L.; Malina, R.; Mannelli, M.; Marchioro, A.; Martin, J.; Meijers, F.; Meridiani, P.; Meschi, E.; Meyer, T.; Meynet Cordonnier, A.; Michaud, J. F.; Mirabito, L.; Moser, R.; Mossiere, F.; Muffat-Joly, J.; Mulders, M.; Mulon, J.; Murer, E.; Mättig, P.; Oh, A.; Onnela, A.; Oriunno, M.; Orsini, L.; Osborne, J. A.; Paillard, C.; Pal, I.; Papotti, G.; Passardi, G.; Patino-Revuelta, A.; Patras, V.; Perea Solano, B.; Perez, E.; Perinic, G.; Pernot, J. F.; Petagna, P.; Petiot, P.; Petit, P.; Petrilli, A.; Pfeiffer, A.; Piccut, C.; Pimiä, M.; Pintus, R.; Pioppi, M.; Placci, A.; Pollet, L.; Postema, H.; Price, M. J.; Principe, R.; Racz, A.; Radermacher, E.; Ranieri, R.; Raymond, G.; Rebecchi, P.; Rehn, J.; Reynaud, S.; Rezvani Naraghi, H.; Ricci, D.; Ridel, M.; Risoldi, M.; Rodrigues Simoes Moreira, P.; Rohlev, A.; Roiron, G.; Rolandi, G.; Rumerio, P.; Runolfsson, O.; Ryjov, V.; Sakulin, H.; Samyn, D.; Santos Amaral, L. C.; Sauce, H.; Sbrissa, E.; Scharff-Hansen, P.; Schieferdecker, P.; Schlatter, W. D.; Schmitt, B.; Schmuecker, H. G.; Schröder, M.; Schwick, C.; Schäfer, C.; Segoni, I.; Sempere Roldán, P.; Sgobba, S.; Sharma, A.; Siegrist, P.; Sigaud, C.; Sinanis, N.; Sobrier, T.; Sphicas, P.; Spiropulu, M.; Stefanini, G.; Strandlie, A.; Szoncsó, F.; Taylor, B. G.; Teller, O.; Thea, A.; Tournefier, E.; Treille, D.; Tropea, P.; Troska, J.; Tsesmelis, E.; Tsirou, A.; Valls, J.; Van Vulpen, I.; Vander Donckt, M.; Vasey, F.; Vazquez Acosta, M.; Veillet, L.; Vichoudis, P.; Waurick, G.; Wellisch, J. P.; Wertelaers, P.; Wilhelmsson, M.; Willers, I. M.; Winkler, M.; Zanetti, M.; Bertl, W.; Deiters, K.; Dick, P.; Erdmann, W.; Feichtinger, D.; Gabathuler, K.; Hochman, Z.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; Kotlinski, D.; König, S.; Poerschke, P.; Renker, D.; Rohe, T.; Sakhelashvili, T.; Starodumov, A.; Aleksandrov, V.; Behner, F.; Beniozef, I.; Betev, B.; Blau, B.; Brett, A. M.; Caminada, L.; Chen, Z.; Chivarov, N.; Da Silva Di Calafiori, D.; Dambach, S.; Davatz, G.; Delachenal, V.; Della Marina, R.; Dimov, H.; Dissertori, G.; Dittmar, M.; Djambazov, L.; Dröge, M.; Eggel, C.; Ehlers, J.; Eichler, R.; Elmiger, M.; Faber, G.; Freudenreich, K.; Fuchs, J. F.; Georgiev, G. M.; Grab, C.; Haller, C.; Herrmann, J.; Hilgers, M.; Hintz, W.; Hofer, Hans; Hofer, Heinz; Horisberger, U.; Horvath, I.; Hristov, A.; Humbertclaude, C.; Iliev, B.; Kastli, W.; Kruse, A.; Kuipers, J.; Langenegger, U.; Lecomte, P.; Lejeune, E.; Leshev, G.; Lesmond, C.; List, B.; Luckey, P. D.; Lustermann, W.; Maillefaud, J. D.; Marchica, C.; Maurisset, A.; Meier, B.; Milenovic, P.; Milesi, M.; Moortgat, F.; Nanov, I.; Nardulli, A.; Nessi-Tedaldi, F.; Panev, B.; Pape, L.; Pauss, F.; Petrov, E.; Petrov, G.; Peynekov, M. M.; Pitzl, D.; Punz, T.; Riboni, P.; Riedlberger, J.; Rizzi, A.; Ronga, F. J.; Roykov, P. A.; Röser, U.; Schinzel, D.; Schöning, A.; Sourkov, A.; Stanishev, K.; Stoenchev, S.; Stöckli, F.; Suter, H.; Trüb, P.; Udriot, S.; Uzunova, D. G.; Veltchev, I.; Viertel, G.; von Gunten, H. P.; Waldmeier-Wicki, S.; Weber, R.; Weber, M.; Weng, J.; Wensveen, M.; Wittgenstein, F.; Zagoursky, K.; Alagoz, E.; Amsler, C.; Chiochia, V.; Hoermann, C.; Regenfus, C.; Robmann, P.; Rommerskirchen, T.; Schmidt, A.; Steiner, S.; Tsirigkas, D.; Wilke, L.; Blyth, S.; Chang, Y. H.; Chen, E. A.; Go, A.; Hung, C. C.; Kuo, C. M.; Li, S. W.; Lin, W.; Chang, P.; Chao, Y.; Chen, K. F.; Gao, Z.; Hou, G. W. S.; Hsiung, Y. B.; Lei, Y. J.; Lin, S. W.; Lu, R. S.; Shiu, J. G.; Tzeng, Y. M.; Ueno, K.; Velikzhanin, Y.; Wang, C. C.; Wang, M.-Z.; Aydin, S.; Azman, A.; Bakirci, M. N.; Basegmez, S.; Cerci, S.; Dumanoglu, I.; Erturk, S.; Eskut, E.; Kayis Topaksu, A.; Kisoglu, H.; Kurt, P.; Ozdemir, K.; Ozdes Koca, N.; Ozkurt, H.; Ozturk, S.; Polatöz, A.; Sogut, K.; Topakli, H.; Vergili, M.; Önengüt, G.; Gamsizkan, H.; Sekmen, S.; Serin-Zeyrek, M.; Sever, R.; Zeyrek, M.; Deliomeroglu, M.; Gülmez, E.; Isiksal, E.; Kaya, M.; Kaya, O.; Ozkorucuklu, S.; Sonmez, N.; Grinev, B.; Lyubynskiy, V.; Senchyshyn, V.; Levchuk, L.; Lukyanenko, S.; Soroka, D.; Sorokin, P.; Zub, S.; Anjum, A.; Baker, N.; Hauer, T.; McClatchey, R.; Odeh, M.; Rogulin, D.; Solomonides, A.; Brooke, J. J.; Croft, R.; Cussans, D.; Evans, D.; Frazier, R.; Grant, N.; Hansen, M.; Head, R. D.; Heath, G. P.; Heath, H. F.; Hill, C.; Huckvale, B.; Jackson, J.; Lynch, C.; Mackay, C. K.; Metson, S.; Nash, S. J.; Newbold, D. M.; Presland, A. D.; Probert, M. G.; Reid, E. C.; Smith, V. J.; Tapper, R. J.; Walton, R.; Bateman, E.; Bell, K. W.; Brown, R. M.; Camanzi, B.; Church, I. T.; Cockerill, D. J. A.; Cole, J. E.; Connolly, J. F.; Coughlan, J. A.; Flower, P. S.; Ford, P.; Francis, V. B.; French, M. J.; Galagedera, S. B.; Gannon, W.; Gay, A. P. R.; Geddes, N. I.; Greenhalgh, R. J. S.; Halsall, R. N. J.; Haynes, W. J.; Hill, J. A.; Jacob, F. R.; Jeffreys, P. W.; Jones, L. L.; Kennedy, B. W.; Lintern, A. L.; Lodge, A. B.; Maddox, A. J.; Morrissey, Q. R.; Murray, P.; Patrick, G. N.; Pattison, C. A. X.; Pearson, M. R.; Quinton, S. P. H.; Rogers, G. J.; Salisbury, J. G.; Shah, A. A.; Shepherd-Themistocleous, C. H.; Smith, B. J.; Sproston, M.; Stephenson, R.; Taghavi, S.; Tomalin, I. R.; Torbet, M. J.; Williams, J. H.; Womersley, W. J.; Worm, S. D.; Xing, F.; Apollonio, M.; Arteche, F.; Bainbridge, R.; Barber, G.; Barrillon, P.; Batten, J.; Beuselinck, R.; Brambilla Hall, P. M.; Britton, D.; Cameron, W.; Clark, D. E.; Clark, I. W.; Colling, D.; Cripps, N.; Davies, G.; Della Negra, M.; Dewhirst, G.; Dris, S.; Foudas, C.; Fulcher, J.; Futyan, D.; Graham, D. J.; Greder, S.; Greenwood, S.; Hall, G.; Hassard, J. F.; Hays, J.; Iles, G.; Kasey, V.; Khaleeq, M.; Leaver, J.; Lewis, P.; MacEvoy, B. C.; Maroney, O.; McLeod, E. M.; Miller, D. G.; Nash, J.; Nikitenko, A.; Noah Messomo, E.; Noy, M.; Papageorgiou, A.; Pesaresi, M.; Petridis, K.; Price, D. R.; Qu, X.; Raymond, D. M.; Rose, A.; Rutherford, S.; Ryan, M. J.; Sciacca, F.; Seez, C.; Sharp, P.; Sidiropoulos, G.; Stettler, M.; Stoye, M.; Striebig, J.; Takahashi, M.; Tallini, H.; Tapper, A.; Timlin, C.; Toudup, L.; Virdee, T.; Wakefield, S.; Walsham, P.; Wardrope, D.; Wingham, M.; Zhang, Y.; Zorba, O.; Da Via, C.; Goitom, I.; Hobson, P. R.; Imrie, D. C.; Reid, I.; Selby, C.; Sharif, O.; Teodorescu, L.; Watts, S. J.; Yaselli, I.; Hazen, E.; Heering, A.; Heister, A.; Lawlor, C.; Lazic, D.; Machado, E.; Rohlf, J.; Sulak, L.; Varela Rodriguez, F.; Wu, S. X.; Avetisyan, A.; Bose, T.; Christofek, L.; Cutts, D.; Esen, S.; Hooper, R.; Landsberg, G.; Narain, M.; Nguyen, D.; Speer, T.; Tsang, K. V.; Breedon, R.; Case, M.; Chertok, M.; Conway, J.; Cox, P. T.; Dolen, J.; Erbacher, R.; Fisyak, Y.; Friis, E.; Grim, G.; Holbrook, B.; Ko, W.; Kopecky, A.; Lander, R.; Lin, F. C.; Lister, A.; Maruyama, S.; Pellett, D.; Rowe, J.; Searle, M.; Smith, J.; Soha, A.; Squires, M.; Tripathi, M.; Vasquez Sierra, R.; Veelken, C.; Andreev, V.; Arisaka, K.; Bonushkin, Y.; Chandramouly, S.; Cline, D.; Cousins, R.; Erhan, S.; Hauser, J.; Ignatenko, M.; Jarvis, C.; Lisowski, B.; Matthey, C.; Mohr, B.; Mumford, J.; Otwinowski, S.; Pischalnikov, Y.; Rakness, G.; Schlein, P.; Shi, Y.; Tannenbaum, B.; Tucker, J.; Valuev, V.; Wallny, R.; Wang, H. G.; Yang, X.; Zheng, Y.; Andreeva, J.; Babb, J.; Campana, S.; Chrisman, D.; Clare, R.; Ellison, J.; Fortin, D.; Gary, J. W.; Gorn, W.; Hanson, G.; Jeng, G. Y.; Kao, S. C.; Layter, J. G.; Liu, F.; Liu, H.; Luthra, A.; Pasztor, G.; Rick, H.; Satpathy, A.; Shen, B. C.; Stringer, R.; Sytnik, V.; Tran, P.; Villa, S.; Wilken, R.; Wimpenny, S.; Zer-Zion, D.; Branson, J. G.; Coarasa Perez, J. A.; Dusinberre, E.; Kelley, R.; Lebourgeois, M.; Letts, J.; Lipeles, E.; Mangano, B.; Martin, T.; Mojaver, M.; Muelmenstaedt, J.; Norman, M.; Paar, H. P.; Petrucci, A.; Pi, H.; Pieri, M.; Rana, A.; Sani, M.; Sharma, V.; Simon, S.; White, A.; Würthwein, F.; Yagil, A.; Affolder, A.; Allen, A.; Campagnari, C.; D'Alfonso, M.; Dierlamm, A.; Garberson, J.; Hale, D.; Incandela, J.; Kalavase, P.; Koay, S. A.; Kovalskyi, D.; Krutelyov, V.; Kyre, S.; Lamb, J.; Lowette, S.; Nikolic, M.; Pavlunin, V.; Rebassoo, F.; Ribnik, J.; Richman, J.; Rossin, R.; Shah, Y. S.; Stuart, D.; Swain, S.; Vlimant, J. R.; White, D.; Witherell, M.; Bornheim, A.; Bunn, J.; Chen, J.; Denis, G.; Galvez, P.; Gataullin, M.; Legrand, I.; Litvine, V.; Ma, Y.; Mao, R.; Nae, D.; Narsky, I.; Newman, H. B.; Orimoto, T.; Rogan, C.; Shevchenko, S.; Steenberg, C.; Su, X.; Thomas, M.; Timciuc, V.; van Lingen, F.; Veverka, J.; Voicu, B. R.; Weinstein, A.; Wilkinson, R.; Xia, Y.; Yang, Y.; Zhang, L. Y.; Zhu, K.; Zhu, R. Y.; Ferguson, T.; Jang, D. W.; Jun, S. Y.; Paulini, M.; Russ, J.; Terentyev, N.; Vogel, H.; Vorobiev, I.; Bunce, M.; Cumalat, J. P.; Dinardo, M. E.; Drell, B. R.; Ford, W. T.; Givens, K.; Heyburn, B.; Johnson, D.; Nauenberg, U.; Stenson, K.; Wagner, S. R.; Agostino, L.; Alexander, J.; Blekman, F.; Cassel, D.; Das, S.; Duboscq, J. E.; Gibbons, L. K.; Heltsley, B.; Jones, C. D.; Kuznetsov, V.; Patterson, J. R.; Riley, D.; Ryd, A.; Stroiney, S.; Sun, W.; Thom, J.; Vaughan, J.; Wittich, P.; Beetz, C. P.; Cirino, G.; Podrasky, V.; Sanzeni, C.; Winn, D.; Abdullin, S.; Afaq, M. A.; Albrow, M.; Amundson, J.; Apollinari, G.; Atac, M.; Badgett, W.; Bakken, J. A.; Baldin, B.; Banicz, K.; Bauerdick, L. A. T.; Baumbaugh, A.; Berryhill, J.; Bhat, P. C.; Binkley, M.; Bloch, I.; Borcherding, F.; Boubekeur, A.; Bowden, M.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chevenier, G.; Chlebana, F.; Churin, I.; Cihangir, S.; Dagenhart, W.; Demarteau, M.; Dykstra, D.; Eartly, D. P.; Elias, J. E.; Elvira, V. D.; Evans, D.; Fisk, I.; Freeman, J.; Gaines, I.; Gartung, P.; Geurts, F. J. M.; Giacchetti, L.; Glenzinski, D. A.; Gottschalk, E.; Grassi, T.; Green, D.; Grimm, C.; Guo, Y.; Gutsche, O.; Hahn, A.; Hanlon, J.; Harris, R. M.; Hesselroth, T.; Holm, S.; Holzman, B.; James, E.; Jensen, H.; Johnson, M.; Joshi, U.; Klima, B.; Kossiakov, S.; Kousouris, K.; Kowalkowski, J.; Kramer, T.; Kwan, S.; Lei, C. M.; Leininger, M.; Los, S.; Lueking, L.; Lukhanin, G.; Lusin, S.; Maeshima, K.; Marraffino, J. M.; Mason, D.; McBride, P.; Miao, T.; Moccia, S.; Mokhov, N.; Mrenna, S.; Murray, S. J.; Newman-Holmes, C.; Noeding, C.; O'Dell, V.; Paterno, M.; Petravick, D.; Pordes, R.; Prokofyev, O.; Ratnikova, N.; Ronzhin, A.; Sekhri, V.; Sexton-Kennedy, E.; Sfiligoi, I.; Shaw, T. M.; Skup, E.; Smith, R. P.; Spalding, W. J.; Spiegel, L.; Stavrianakou, M.; Stiehr, G.; Stone, A. L.; Suzuki, I.; Tan, P.; Tanenbaum, W.; Temple, L. E.; Tkaczyk, S.; Uplegger, L.; Vaandering, E. W.; Vidal, R.; Wands, R.; Wenzel, H.; Whitmore, J.; Wicklund, E.; Wu, W. M.; Wu, Y.; Yarba, J.; Yarba, V.; Yumiceva, F.; Yun, J. C.; Zimmerman, T.; Acosta, D.; Avery, P.; Barashko, V.; Bartalini, P.; Bourilkov, D.; Cavanaugh, R.; Dolinsky, S.; Drozdetskiy, A.; Field, R. D.; Fu, Y.; Furic, I. K.; Gorn, L.; Holmes, D.; Kim, B. J.; Klimenko, S.; Konigsberg, J.; Korytov, A.; Kotov, K.; Levchenko, P.; Madorsky, A.; Matchev, K.; Mitselmakher, G.; Pakhotin, Y.; Prescott, C.; Ramond, L.; Ramond, P.; Schmitt, M.; Scurlock, B.; Stasko, J.; Stoeck, H.; Wang, D.; Yelton, J.; Gaultney, V.; Kramer, L.; Lebolo, L. M.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Adams, T.; Askew, A.; Atramentov, O.; Bertoldi, M.; Dharmaratna, W. G. D.; Gershtein, Y.; Gleyzer, S. V.; Hagopian, S.; Hagopian, V.; Jenkins, C. J.; Johnson, K. F.; Prosper, H.; Simek, D.; Thomaston, J.; Baarmand, M.; Baksay, L.; Guragain, S.; Hohlmann, M.; Mermerkaya, H.; Ralich, R.; Vodopiyanov, I.; Adams, M. R.; Anghel, I. M.; Apanasevich, L.; Barannikova, O.; Bazterra, V. E.; Betts, R. R.; Dragoiu, C.; Garcia-Solis, E. J.; Gerber, C. E.; Hofman, D. J.; Hollis, R.; Iordanova, A.; Khalatian, S.; Mironov, C.; Shabalina, E.; Smoron, A.; Varelas, N.; Akgun, U.; Albayrak, E. A.; Ayan, A. S.; Briggs, R.; Cankocak, K.; Clarida, W.; Cooper, A.; Debbins, P.; Duru, F.; Fountain, M.; McCliment, E.; Merlo, J. P.; Mestvirishvili, A.; Miller, M. J.; Moeller, A.; Newsom, C. R.; Norbeck, E.; Olson, J.; Onel, Y.; Perera, L.; Schmidt, I.; Wang, S.; Yetkin, T.; Anderson, E. W.; Chakir, H.; Hauptman, J. M.; Lamsa, J.; Barnett, B. A.; Blumenfeld, B.; Chien, C. Y.; Giurgiu, G.; Gritsan, A.; Kim, D. W.; Lae, C. K.; Maksimovic, P.; Swartz, M.; Tran, N.; Baringer, P.; Bean, A.; Chen, J.; Coppage, D.; Grachov, O.; Murray, M.; Radicci, V.; Wood, J. S.; Zhukova, V.; Bandurin, D.; Bolton, T.; Kaadze, K.; Kahl, W. E.; Maravin, Y.; Onoprienko, D.; Sidwell, R.; Wan, Z.; Dahmes, B.; Gronberg, J.; Hollar, J.; Lange, D.; Wright, D.; Wuest, C. R.; Baden, D.; Bard, R.; Eno, S. C.; Ferencek, D.; Hadley, N. J.; Kellogg, R. G.; Kirn, M.; Kunori, S.; Lockner, E.; Ratnikov, F.; Santanastasio, F.; Skuja, A.; Toole, T.; Wang, L.; Wetstein, M.; Alver, B.; Ballintijn, M.; Bauer, G.; Busza, W.; Gomez Ceballos, G.; Hahn, K. A.; Harris, P.; Klute, M.; Kravchenko, I.; Li, W.; Loizides, C.; Ma, T.; Nahn, S.; Paus, C.; Pavlon, S.; Piedra Gomez, J.; Roland, C.; Roland, G.; Rudolph, M.; Stephans, G.; Sumorok, K.; Vaurynovich, S.; Wenger, E. A.; Wyslouch, B.; Bailleux, D.; Cooper, S.; Cushman, P.; DeBenedetti, A.; Dolgopolov, A.; Dudero, P. R.; Egeland, R.; Franzoni, G.; Gilbert, W. J.; Gong, D.; Grahl, J.; Haupt, J.; Klapoetke, K.; Kronkvist, I.; Kubota, Y.; Mans, J.; Rusack, R.; Sengupta, S.; Sherwood, B.; Singovsky, A.; Vikas, P.; Zhang, J.; Booke, M.; Cremaldi, L. M.; Godang, R.; Kroeger, R.; Reep, M.; Reidy, J.; Sanders, D. A.; Sonnek, P.; Summers, D.; Watkins, S.; Bloom, K.; Bockelman, B.; Claes, D. R.; Dominguez, A.; Eads, M.; Furukawa, M.; Keller, J.; Kelly, T.; Lundstedt, C.; Malik, S.; Snow, G. R.; Swanson, D.; Ecklund, K. M.; Iashvili, I.; Kharchilava, A.; Kumar, A.; Strang, M.; Alverson, G.; Barberis, E.; Boeriu, O.; Eulisse, G.; McCauley, T.; Musienko, Y.; Muzaffar, S.; Osborne, I.; Reucroft, S.; Swain, J.; Taylor, L.; Tuura, L.; Gobbi, B.; Kubantsev, M.; Kubik, A.; Ofierzynski, R. A.; Schmitt, M.; Spencer, E.; Stoynev, S.; Szleper, M.; Velasco, M.; Won, S.; Andert, K.; Baumbaugh, B.; Beiersdorf, B. A.; Castle, L.; Chorny, J.; Goussiou, A.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kolberg, T.; Marchant, J.; Marinelli, N.; McKenna, M.; Ruchti, R.; Vigneault, M.; Wayne, M.; Wiand, D.; Bylsma, B.; Durkin, L. S.; Gilmore, J.; Gu, J.; Killewald, P.; Ling, T. Y.; Rush, C. J.; Sehgal, V.; Williams, G.; Adam, N.; Chidzik, S.; Denes, P.; Elmer, P.; Garmash, A.; Gerbaudo, D.; Halyo, V.; Jones, J.; Marlow, D.; Olsen, J.; Piroué, P.; Stickland, D.; Tully, C.; Werner, J. S.; Wildish, T.; Wynhoff, S.; Xie, Z.; Huang, X. T.; Lopez, A.; Mendez, H.; Ramirez Vargas, J. E.; Zatserklyaniy, A.; Apresyan, A.; Arndt, K.; Barnes, V. E.; Bolla, G.; Bortoletto, D.; Bujak, A.; Everett, A.; Fahling, M.; Garfinkel, A. F.; Gutay, L.; Ippolito, N.; Kozhevnikov, Y.; Laasanen, A. T.; Liu, C.; Maroussov, V.; Medved, S.; Merkel, P.; Miller, D. H.; Miyamoto, J.; Neumeister, N.; Pompos, A.; Roy, A.; Sedov, A.; Shipsey, I.; Cuplov, V.; Parashar, N.; Bargassa, P.; Lee, S. J.; Liu, J. H.; Maronde, D.; Matveev, M.; Nussbaum, T.; Padley, B. P.; Roberts, J.; Tumanov, A.; Bodek, A.; Budd, H.; Cammin, J.; Chung, Y. S.; DeBarbaro, P.; Demina, R.; Ginther, G.; Gotra, Y.; Korjenevski, S.; Miner, D. C.; Sakumoto, W.; Slattery, P.; Zielinski, M.; Bhatti, A.; Demortier, L.; Goulianos, K.; Hatakeyama, K.; Mesropian, C.; Bartz, E.; Chuang, S. H.; Doroshenko, J.; Halkiadakis, E.; Jacques, P. F.; Khits, D.; Lath, A.; Macpherson, A.; Plano, R.; Rose, K.; Schnetzer, S.; Somalwar, S.; Stone, R.; Watts, T. L.; Cerizza, G.; Hollingsworth, M.; Lazoflores, J.; Ragghianti, G.; Spanier, S.; York, A.; Aurisano, A.; Golyash, A.; Kamon, T.; Nguyen, C. N.; Pivarski, J.; Safonov, A.; Toback, D.; Weinberger, M.; Akchurin, N.; Berntzon, L.; Carrell, K. W.; Gumus, K.; Jeong, C.; Kim, H.; Lee, S. W.; McGonagill, B. G.; Roh, Y.; Sill, A.; Spezziga, M.; Thomas, R.; Volobouev, I.; Washington, E.; Wigmans, R.; Yazgan, E.; Bapty, T.; Engh, D.; Florez, C.; Johns, W.; Keskinpala, T.; Luiggi Lopez, E.; Neema, S.; Nordstrom, S.; Pathak, S.; Sheldon, P.; Andelin, D.; Arenton, M. W.; Balazs, M.; Buehler, M.; Conetti, S.; Cox, B.; Hirosky, R.; Humphrey, M.; Imlay, R.; Ledovskoy, A.; Phillips, D., II; Powell, H.; Ronquest, M.; Yohay, R.; Anderson, M.; Baek, Y. W.; Bellinger, J. N.; Bradley, D.; Cannarsa, P.; Carlsmith, D.; Crotty, I.; Dasu, S.; Feyzi, F.; Gorski, T.; Gray, L.; Grogg, K. S.; Grothe, M.; Jaworski, M.; Klabbers, P.; Klukas, J.; Lanaro, A.; Lazaridis, C.; Leonard, J.; Loveless, R.; Magrans de Abril, M.; Mohapatra, A.; Ott, G.; Smith, W. H.; Weinberg, M.; Wenman, D.; Atoian, G. S.; Dhawan, S.; Issakov, V.; Neal, H.; Poblaguev, A.; Zeller, M. E.; Abdullaeva, G.; Avezov, A.; Fazylov, M. I.; Gasanov, E. M.; Khugaev, A.; Koblik, Y. N.; Nishonov, M.; Olimov, K.; Umaraliev, A.; Yuldashev, B. S.

2008-08-01

The Compact Muon Solenoid (CMS) detector is described. The detector operates at the Large Hadron Collider (LHC) at CERN. It was conceived to study proton-proton (and lead-lead) collisions at a centre-of-mass energy of 14 TeV (5.5 TeV nucleon-nucleon) and at luminosities up to 1034 cm-2 s-1 (1027 cm-2 s-1). At the core of the CMS detector sits a high-magnetic-field and large-bore superconducting solenoid surrounding an all-silicon pixel and strip tracker, a lead-tungstate scintillating-crystals electromagnetic calorimeter, and a brass-scintillator sampling hadron calorimeter. The iron yoke of the flux-return is instrumented with four stations of muon detectors covering most of the 4π solid angle. Forward sampling calorimeters extend the pseudorapidity coverage to high values (|η| <= 5) assuring very good hermeticity. The overall dimensions of the CMS detector are a length of 21.6 m, a diameter of 14.6 m and a total weight of 12500 t.

36 CFR § 1280.92 - When are the Presidential library museums open to the public?

Code of Federal Regulations, 2013 CFR

2013-07-01

... library museums open to the public? § 1280.92 Section § 1280.92 Parks, Forests, and Public Property... Apply for Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving...

Robot-assisted versus open sacrocolpopexy: a cost-minimization analysis.

PubMed

Elliott, Christopher S; Hsieh, Michael H; Sokol, Eric R; Comiter, Craig V; Payne, Christopher K; Chen, Bertha

2012-02-01

Abdominal sacrocolpopexy is considered a standard of care operation for apical vaginal vault prolapse repair. Using outcomes at our center we evaluated whether the robotic approach to sacrocolpopexy is as cost-effective as the open approach. After obtaining institutional review board approval we performed cost-minimization analysis in a retrospective cohort of patients who underwent sacrocolpopexy at our institution between 2006 and 2010. Threshold values, that is model variable values at which the most cost effective approach crosses over to an alternative approach, were determined by testing model variables over realistic ranges using sensitivity analysis. Hospital billing data were also evaluated to confirm our findings. Operative time was similar for robotic and open surgery (226 vs 221 minutes) but postoperative length of stay differed significantly (1.0 vs 3.3 days, p <0.001). Base case analysis revealed an overall 10% cost savings for robot-assisted vs open sacrocolpopexy ($10,178 vs $11,307). Tornado analysis suggested that the number of institutional robotic cases done annually, length of stay and cost per hospitalization day in the postoperative period were the largest drivers of cost. Analysis of our hospital billing data showed a similar trend with robotic surgery costing 4.2% less than open surgery. A robot-assisted approach to sacrocolpopexy can be equally or less costly than an open approach. This depends on a sufficient institutional robotic case volume and a shorter postoperative stay for patients who undergo the robot-assisted procedure. Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Robotic thoracic surgery results in shorter hospital stay and lower postoperative pain compared to open thoracotomy: a matched pairs analysis.

PubMed

Darr, Christopher; Cheufou, Danjouma; Weinreich, Gerhard; Hachenberg, Thomas; Aigner, Clemens; Kampe, Sandra

2017-10-01

To evaluate postoperative pain intensity and length of hospital stay after open or robotic thoracic surgery in a standardized postoperative pain therapy setting. In the present retrospective (oberservation period: January 2015 until January 2016) study we matched data of 38 patients with robotic thoracic surgery ("robotic patients"; age: 62.2 years, male gender: 42.1%) with 38 patients with open thoracic surgery ("open patients"; age: 62.5 years, male gender: 42.1%). Power analysis indicated that 36 patients per group would be required. 68% of all patients received an epidural catheter, and 32% a systemic opioid based analgesia. Postoperative pain intensity in "robotic patients" was lower at rest on postoperative day 3-5 compared to "open patients" (NRS POD 3 robotic surgery 0.5±1.0 vs. open surgery 1.0±1.6, p = 0.04; NRS POD 4 robotic surgery 0,5 ± 1.0 vs. open surgery 1.1±1.3, p=0.04; NRS POD 5 robotic surgery 0.7 ± 1.0 vs. open surgery 1.5±1.5, p=0.003). Chest tube duration was shorter in "robotic patients" (2.9 ± 2.0 days vs. 4.9 ± 2.2 days; p < 0.001). Moreover, length of hospital stay was shorter in "robotic patients" than in "open patients" (6.9 days vs. 8.0 days; p = 0.02). There was no significant difference in postoperative opioid consumption between the groups. Nearly 95% of patients were discharged home with an oral opioid in both groups. Patients after robotic pulmonary resection experience lower postoperative pain and are discharged earlier from hospital than patients after open thoracic surgery. The study design is retrospectively.

["Abdominal dressing" - a new method of treatment for open abdomen following secondary peritonitis].

PubMed

Wild, T; Stremitzer, S; Budzanowski, A; Rinder, H; Tamandl, D; Zeisel, C; Hölzenbein, T; Sautner, T

2004-05-01

Treatment of open abdomen following secondary peritonitis is a challenge for surgery and intensive care units (ICU). The aim of this study was to compare three different concurrent treatment strategies. Patients suffering an open abdomen following surgery for secondary peritonitis at the Department of General Surgery from 01/01 to 12/03 were investigated. Factor studied: duration of open abdomen, incidence of multi-organ failure, need for surgical revisions, length of stay (LOS) in ICU, nursing requirements (change of dressing/day), survival and integrity of abdominal wall after discharge. Treatment strategies included: open packing (OP), classic vacuum assisted (V.A.C.(R))-therapy with silicone net protection for the intestine (CV) and V.A.C.(R)-therapy with "abdominal dressing" a newly developed meshed polyvinyl wrap (AD). 21 patients were studied: 5 patients were treated with OP, 8 patients with CV and 8 patients with AD. Mean LOS was 65 (OP) vs. 53 (CV) vs. 42 (AD) days (NS), peritonitis related death was 3 (OP) vs. 1 (CV) vs. 0 (AD) (p < 0.05 Chisquare test). Median nursing effort was 4 dressings/day (OP), 0.5 (CV) and 0.5 (AD) (p < 0.005 OP vs CV, AD Kruskal-Wallis test). The "abdominal dressing"-therapy seems to be a more efficient treatment option in patients suffering from open abdomen following secondary peritonitis. A trend towards shorter ICU-LOS, lower mortality rates and reduced nursing requirements support our hypothesis.

2011 Astronomy Day at McDonald Observatory

NASA Astrophysics Data System (ADS)

Preston, Sandra; Hemeway, M.; Wetzel, M.

2012-01-01

Our philosophy is that everyday is Astronomy Day because the McDonald Observatory's Frank N. Bash Visitors Center is open 362 days a year. So, how did we create a special celebration for the "Astronomy Day” declared by the Astronomical League? During September 26-29 we conducted 20 videoconferences and served 12,559 students with "Astronomy Day” programming. Connect2Texas provides bridging for a network of Texas-based museums and cultural, historical, and scientific organizations that offer educational content to schools throughout the state via videoconferencing. Connect2Texas connected McDonald Observatory to 334 schools; most of these schools were in Texas, but schools in a dozen other states also participated. While most schools had a "view-only" connection, at least 20 of the schools had interactive connections, whereby the students could ask questions of the presenter. Connect2Texas also collects evaluation information from the participating schools that we will use to produce a report for our funders and make modifications to future programs as need be. The videoconferences were offered free of charge. The theme for the 2011 Astronomy Day program was the Year of the Solar System, which aligns with NASA's theme for 2011 and 2012. By aligning with this NASA theme, we could leverage NASA artwork and materials to both advertise and enrich the learning experience. Videoconference materials also included pre- and post-videoconference assessment sheets, an inquiry based activity, and pre- and post-videoconference activities, all of which were made available online. One of the lessons learned from past Astronomy Day videoconferences is that the days the Astronomical League declares as "Astronomy Day” are not always good days for Texas schools to participate. So, we choose an Astronomy Day that meets the needs of Texas schools and our schedule - so any day can be Astronomy Day. 2011 Astronomy Day was made possible by The Meyer-Levy Charitable Trust.

Feasibility study for a biomedical experimental facility based on LEIR at CERN.

PubMed

Abler, Daniel; Garonna, Adriano; Carli, Christian; Dosanjh, Manjit; Peach, Ken

2013-07-01

In light of the recent European developments in ion beam therapy, there is a strong interest from the biomedical research community to have more access to clinically relevant beams. Beamtime for pre-clinical studies is currently very limited and a new dedicated facility would allow extensive research into the radiobiological mechanisms of ion beam radiation and the development of more refined techniques of dosimetry and imaging. This basic research would support the current clinical efforts of the new treatment centres in Europe (for example HIT, CNAO and MedAustron). This paper presents first investigations on the feasibility of an experimental biomedical facility based on the CERN Low Energy Ion Ring LEIR accelerator. Such a new facility could provide beams of light ions (from protons to neon ions) in a collaborative and cost-effective way, since it would rely partly on CERN's competences and infrastructure. The main technical challenges linked to the implementation of a slow extraction scheme for LEIR and to the design of the experimental beamlines are described and first solutions presented. These include introducing new extraction septa into one of the straight sections of the synchrotron, changing the power supply configuration of the magnets, and designing a new horizontal beamline suitable for clinical beam energies, and a low-energy vertical beamline for particular radiobiological experiments.

Feasibility study for a biomedical experimental facility based on LEIR at CERN

PubMed Central

Abler, Daniel; Garonna, Adriano; Carli, Christian; Dosanjh, Manjit; Peach, Ken

2013-01-01

In light of the recent European developments in ion beam therapy, there is a strong interest from the biomedical research community to have more access to clinically relevant beams. Beamtime for pre-clinical studies is currently very limited and a new dedicated facility would allow extensive research into the radiobiological mechanisms of ion beam radiation and the development of more refined techniques of dosimetry and imaging. This basic research would support the current clinical efforts of the new treatment centres in Europe (for example HIT, CNAO and MedAustron). This paper presents first investigations on the feasibility of an experimental biomedical facility based on the CERN Low Energy Ion Ring LEIR accelerator. Such a new facility could provide beams of light ions (from protons to neon ions) in a collaborative and cost-effective way, since it would rely partly on CERN's competences and infrastructure. The main technical challenges linked to the implementation of a slow extraction scheme for LEIR and to the design of the experimental beamlines are described and first solutions presented. These include introducing new extraction septa into one of the straight sections of the synchrotron, changing the power supply configuration of the magnets, and designing a new horizontal beamline suitable for clinical beam energies, and a low-energy vertical beamline for particular radiobiological experiments. PMID:23824122

The beam test of muon detector parameters for the SHiP experiment at CERN

NASA Astrophysics Data System (ADS)

Likhacheva, V. L.; Kudenko, Yu. G.; Mefodiev, A. V.; Mineev, O. V.; Khotyantsev, A. N.

2018-01-01

Scintillation detectors based on extruded plastics have been tested in a 10 GeV/c beam at CERN. The scintillation signal readout was provided using optical wavelength shifting fibers Y11 Kuraray and Hamamatsu MPPC micropixel avalanche photodiodes. The light yield was scanned along and across the detectors. Time resolution was found by fitting the MPPC digitized pulse rise and other methods.

Open Education and the Open Science Economy

ERIC Educational Resources Information Center

Peters, Michael A.

2009-01-01

Openness as a complex code word for a variety of digital trends and movements has emerged as an alternative mode of "social production" based on the growing and overlapping complexities of open source, open access, open archiving, open publishing, and open science. This paper argues that the openness movement with its reinforcing structure of…

A perioperative cost analysis comparing single-level minimally invasive and open transforaminal lumbar interbody fusion.

PubMed

Singh, Kern; Nandyala, Sreeharsha V; Marquez-Lara, Alejandro; Fineberg, Steven J; Oglesby, Mathew; Pelton, Miguel A; Andersson, Gunnar B; Isayeva, Darya; Jegier, Briana J; Phillips, Frank M

2014-08-01

Emerging literature suggests superior clinical short- and long-term outcomes of MIS (minimally invasive surgery) TLIFs (transforaminal lumbar interbody fusion) versus open fusions. Few studies to date have analyzed the cost differences between the two techniques and their relationship to acute clinical outcomes. The purpose of the study was to determine the differences in hospitalization costs and payments for patients treated with primary single-level MIS versus open TLIF. The impact of clinical outcomes and their contribution to financial differences was explored as well. This study was a nonrandomized, nonblinded prospective review. Sixty-six consecutive patients undergoing a single-level TLIF (open/MIS) were analyzed (33 open, 33 MIS). Patients in either cohort (MIS/open) were matched based on race, sex, age, smoking status, medical comorbidities (Charlson Comorbidity index), payer, and diagnosis. Every patient in the study had a diagnosis of either degenerative disc disease or spondylolisthesis and stenosis. Operative time (minutes), length of stay (LOS, days), estimated blood loss (EBL, mL), anesthesia time (minutes), Visual Analog Scale (VAS) scores, and hospital cost/payment amount were assessed. The MIS and open TLIF groups were compared based on clinical outcomes measures and hospital cost/payment data using SPSS version 20.0 for statistical analysis. The two groups were compared using bivariate chi-squared analysis. Mann-Whitney tests were used for non-normal distributed data. Effect size estimate was calculated with the Cohen d statistic and the r statistic with a 95% confidence interval. Average surgical time was shorter for the MIS than the open TLIF group (115.8 minutes vs. 186.0 minutes respectively; p=.001). Length of stay was also reduced for the MIS versus the open group (2.3 days vs. 2.9 days, respectively; p=.018). Average anesthesia time and EBL were also lower in the MIS group (p<.001). VAS scores decreased for both groups, although these

Rotation periods of open-cluster stars, 3

NASA Technical Reports Server (NTRS)

Prosser, Charles F.; Shetrone, Matthew D.; Dasgupta, Amil; Backman, Dana E.; Laaksonen, Bentley D.; Baker, Shawn W.; Marschall, Laurence A.; Whitney, Barbara A.; Kuijken, Konrad; Stauffer, John R.

1995-01-01

We present the results from a photometric monitoring program of 15 open cluster stars and one weak-lined T Tauri star during late 1993/early 1994. Several show rotators which are members of the Alpha Persei, Pleiades, and Hyades open clusters have been monitored and period estimates derived. Using all available Pleiades stars with photometric periods together with current X-ray flux measurements, we illustrate the X-ray activity/rotation relation among Pleiades late-G/K dwarfs. The data show a clear break in the rotation-activity relation around P approximately 6-7 days -- in general accordance with previous results using more heterogeneous samples of G/K stars.

Minimally Invasive versus Open Approach for Right-Sided Colectomy: A Study in 12,006 Patients from the Dutch Surgical Colorectal Audit.

PubMed

Bosker, Robbert J I; Van't Riet, Esther; de Noo, Mirre; Vermaas, Maarten; Karsten, Tom M; Pierie, Jean-Pierre

2018-02-07

There is ongoing debate whether laparoscopic right colectomy is superior to open surgery. The purpose of this study was to address this issue and arrive at a consensus using data from a national database. Patients who underwent elective open or laparoscopic right colectomy for colorectal cancer during the period 2009-2013 were identified from the Dutch Surgical Colorectal Audit. Complications that occurred within 30 days after surgery and 30-day mortality rates were calculated and compared between open and laparoscopic resection. In total, 12,006 patients underwent elective open or laparoscopic surgery for right-sided colorectal cancer. Of these, 6,683 (55.7%) underwent open resection and 5,323 (44.3%) underwent laparoscopic resection. Complications occurred within 30 days after surgery in the laparoscopic group in 26.1% of patients and in 32.1% of patients in the open group (p < 0.001). Thirty-day mortality was also significantly lower in the laparoscopic group (2.2 vs. 3.6% p < 0.001). In this non-randomized, descriptive study conducted in the Netherlands, open right colectomy seems to have a higher risk for complications and mortality as compared to laparoscopic right colectomy, even after correction for confounding factors. © 2018 S. Karger AG, Basel.

Endeavour Grand Opening Ceremony

NASA Image and Video Library

2012-10-30

A government Transfer Order for Excess Personal Property is seen framed outside the office of President and CEO, California Science Center, Jeffrey N. Rudolph, on Tuesday, Oct. 30, 2012, in Los Angeles. The grand opening ceremony for the California Science center's Samuel Oschin Space Shuttle Endeavour Display Pavilion took place on Tuesday, Oct. 30, 2012. Endeavour, built as a replacement for space shuttle Challenger, completed 25 missions, spent 299 days in orbit, and orbited Earth 4,671 times while traveling 122,883,151 miles. Photo Credit: (NASA/Bill Ingalls)

First results from the CERN axion solar telescope.

PubMed

Zioutas, K; Andriamonje, S; Arsov, V; Aune, S; Autiero, D; Avignone, F T; Barth, K; Belov, A; Beltrán, B; Bräuninger, H; Carmona, J M; Cebrián, S; Chesi, E; Collar, J I; Creswick, R; Dafni, T; Davenport, M; Di Lella, L; Eleftheriadis, C; Englhauser, J; Fanourakis, G; Farach, H; Ferrer, E; Fischer, H; Franz, J; Friedrich, P; Geralis, T; Giomataris, I; Gninenko, S; Goloubev, N; Hasinoff, M D; Heinsius, F H; Hoffmann, D H H; Irastorza, I G; Jacoby, J; Kang, D; Königsmann, K; Kotthaus, R; Krcmar, M; Kousouris, K; Kuster, M; Lakić, B; Lasseur, C; Liolios, A; Ljubicić, A; Lutz, G; Luzón, G; Miller, D W; Morales, A; Morales, J; Mutterer, M; Nikolaidis, A; Ortiz, A; Papaevangelou, T; Placci, A; Raffelt, G; Ruz, J; Riege, H; Sarsa, M L; Savvidis, I; Serber, W; Serpico, P; Semertzidis, Y; Stewart, L; Vieira, J D; Villar, J; Walckiers, L; Zachariadou, K

2005-04-01

Hypothetical axionlike particles with a two-photon interaction would be produced in the sun by the Primakoff process. In a laboratory magnetic field ("axion helioscope"), they would be transformed into x-rays with energies of a few keV. Using a decommissioned Large Hadron Collider test magnet, the CERN Axion Solar Telescope ran for about 6 months during 2003. The first results from the analysis of these data are presented here. No signal above background was observed, implying an upper limit to the axion-photon coupling g(agamma)<1.16x10(-10) GeV-1 at 95% C.L. for m(a) less, similar 0.02 eV. This limit, assumption-free, is comparable to the limit from stellar energy-loss arguments and considerably more restrictive than any previous experiment over a broad range of axion masses.

Controlled longitudinal emittance blow-up using band-limited phase noise in CERN PSB

NASA Astrophysics Data System (ADS)

Quartullo, D.; Shaposhnikova, E.; Timko, H.

2017-07-01

Controlled longitudinal emittance blow-up (from 1 eVs to 1.4 eVs) for LHC beams in the CERN PS Booster is currently achievied using sinusoidal phase modulation of a dedicated high-harmonic RF system. In 2021, after the LHC injectors upgrade, 3 eVs should be extracted to the PS. Even if the current method may satisfy the new requirements, it relies on low-power level RF improvements. In this paper another method of blow-up was considered, that is the injection of band-limited phase noise in the main RF system (h=1), never tried in PSB but already used in CERN SPS and LHC, under different conditions (longer cycles). This technique, which lowers the peak line density and therefore the impact of intensity effects in the PSB and the PS, can also be complementary to the present method. The longitudinal space charge, dominant in the PSB, causes significant synchrotron frequency shifts with intensity, and its effect should be taken into account. Another complication arises from the interaction of the phase loop with the injected noise, since both act on the RF phase. All these elements were studied in simulations of the PSB cycle with the BLonD code, and the required blow-up was achieved.

New vertical cryostat for the high field superconducting magnet test station at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vande Craen, A.; Atieh, S.; Bajko, M.

2014-01-29

In the framework of the R and D program for new superconducting magnets for the Large Hadron Collider accelerator upgrades, CERN is building a new vertical test station to test high field superconducting magnets of unprecedented large size. This facility will allow testing of magnets by vertical insertion in a pressurized liquid helium bath, cooled to a controlled temperature between 4.2 K and 1.9 K. The dimensions of the cryostat will allow testing magnets of up to 2.5 m in length with a maximum diameter of 1.5 m and a mass of 15 tons. To allow for a faster insertionmore » and removal of the magnets and reducing the risk of helium leaks, all cryogenics supply lines are foreseen to remain permanently connected to the cryostat. A specifically designed 100 W heat exchanger is integrated in the cryostat helium vessel for a controlled cooling of the magnet from 4.2 K down to 1.9 K in a 3 m{sup 3} helium bath. This paper describes the cryostat and its main functions, focusing on features specifically developed for this project. The status of the construction and the plans for assembly and installation at CERN are also presented.« less

76 FR 21999 - Education and Sharing Day, U.S.A., 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

... remains a beacon of hope for many across the globe because of our open hearts during times of... dedicated his life to improving education and fostering goodwill for all people. His legacy continues to... Sharing Day, U.S.A., reminds us of our obligation to create opportunities for a better tomorrow--life...

Open House at the ESO Headquarters

NASA Astrophysics Data System (ADS)

Madsen, C.

2006-12-01

On 15 October, the ESO Headquarters opened its doors to the public as part of the All-Campus Open House organised in connection with the inauguration of the extension of the underground line U6 from Munich to the Garching campus. The day was blessed with clear skies and plenty of sunshine, and a large number of citizens took advantage of the opportunity to visit the campus. The estimated number of visitors at ESO was close to 3000 people, a record number. Another record was set by the number of ESO staff who, in anticipation of the high num-ber of guests, volunteered to spend their Sunday at work to explain what ESO is doing and why it is important.

Financial performance among adult day centers: results of a national demonstration program.

PubMed

Reifler, B V; Henry, R S; Rushing, J; Yates, M K; Cox, N J; Bradham, D D; McFarlane, M

1997-02-01

This paper describes the financial performance (defined as percent of total expenses covered by net operating revenue) of 16 adult day centers participating in a national demonstration program on day services for people with dementia, including examination of possible predictors of financial performance. Participating sites submitted quarterly financial and utilization reports to the National Program Office. Descriptive statistics summarize the factors believed to influence financial performance. Sites averaged meeting 35% of expenses from self-pay and 29% from government (mainly Medicaid) revenue, totaling 64% of all (cash plus in-kind) expenses met by operating revenue. Examination of center characteristics suggests that factors related to meeting consumer needs, such as being open a full day (i.e., 7:30 am to 6:00 pm) rather than shorter hours, and providing transportation, may be related to improved utilization and, thus, improved financial performance. Higher fees were not related to lower enrollment, census, or revenue. Adult day centers are able to achieve financial viability through a combination of operating (i.e., fee-for-service) and non-operating revenue. Operating revenue is enhanced by placing emphasis on consumer responsiveness, such as being open a full day. Because higher fees were not related to lower utilization, centers should set fees to reflect actual costs. The figure of 64% of expenses met by operating revenue is conservative inasmuch as sites included in-kind revenue as expenses in their budgeting calculations, and percent of cash expenses met by operating revenue would be higher (approximately 75% for this group of centers).

Simultaneous repair of bilateral inguinal hernias: a prospective, randomized study of open, tension-free versus laparoscopic approach.

PubMed

Sarli, L; Iusco, D R; Sansebastiano, G; Costi, R

2001-08-01

No randomized trial exists that specifically addresses the issue of laparoscopic bilateral inguinal hernia repair. The purpose of the present prospective, randomized, controlled, clinical study was to assess short- and long-term results when comparing simultaneous bilateral hernia repair by an open, tension-free anterior approach with laparoscopic "bikini mesh" posterior repair. Forty-three low-risk male patients with bilateral primary inguinal hernia were randomly assigned to undergo either laparoscopic preperitoneal "bikini mesh" hernia repair (TAPP) or open Lichtenstein hernioplasty. There was no difference in operating time between the two groups. The mean cost of laparoscopic hernioplasty was higher (P < 0.001). The intensity of postoperative pain was greater in the open hernia repair group at 24 hours, 48 hours, and 7 days after surgery (P < 0.001), with a greater consumption of pain medication among these patients (P < 0.05). The median time to return to work was 30 days for the open hernia repair group and 16 days for the laparoscopic "bikini mesh" repair group (P < 0.05). Only 1 asymptomatic recurrence (4.3%) was discovered in the open group. The laparoscopic approach to bilateral hernia with "bikini mesh" appears to be preferable to the open Lichtenstein tension-free hernioplasty in terms of the postoperative quality of life and interruption of occupational activity.

Evaluation of open versus closed urine collection systems and development of nosocomial bacteriuria in dogs.

PubMed

Sullivan, Lauren A; Campbell, Vicki L; Onuma, Serene C

2010-07-15

To determine whether use of a closed urine collection system would decrease the incidence of nosocomial bacteriuria in hospitalized dogs, compared with use of an open urine collection system (used, sterile IV bags). Randomized controlled trial. 51 hospitalized dogs requiring indwelling urinary catheterization for >or= 24 hours. Dogs were randomly assigned to an open or closed urine collection system group. A standardized protocol for catheter placement and maintenance was followed for all dogs. A baseline urine sample was collected via cystocentesis for aerobic bacterial culture, with additional urine samples obtained daily from the urine collection reservoir. 27 dogs were assigned to the open urine collection system group, and 24 were assigned to the closed urine collection system group. The incidence of nosocomial bacteriuria in dogs with open urine collection systems (3/27 [11.1%]) was not significantly different from incidence in dogs with closed urine collection systems (2/24 [8.3%]). Median duration of catheterization was 2 days for dogs in both groups; the range was 1 to 7 days for dogs in the open group and 1 to 5 days for dogs in the closed group. Results suggested that for dogs requiring short-term indwelling urinary catheterization, the type of urine collection system (open vs closed) was not associated with likelihood of developing nosocomial bacteriuria. Use of a strict protocol for urinary catheter placement and maintenance was likely key in the low incidence of nosocomial bacteriuria in the present study.

The open science grid

NASA Astrophysics Data System (ADS)

Pordes, Ruth; OSG Consortium; Petravick, Don; Kramer, Bill; Olson, Doug; Livny, Miron; Roy, Alain; Avery, Paul; Blackburn, Kent; Wenaus, Torre; Würthwein, Frank; Foster, Ian; Gardner, Rob; Wilde, Mike; Blatecky, Alan; McGee, John; Quick, Rob

2007-07-01

The Open Science Grid (OSG) provides a distributed facility where the Consortium members provide guaranteed and opportunistic access to shared computing and storage resources. OSG provides support for and evolution of the infrastructure through activities that cover operations, security, software, troubleshooting, addition of new capabilities, and support for existing and engagement with new communities. The OSG SciDAC-2 project provides specific activities to manage and evolve the distributed infrastructure and support it's use. The innovative aspects of the project are the maintenance and performance of a collaborative (shared & common) petascale national facility over tens of autonomous computing sites, for many hundreds of users, transferring terabytes of data a day, executing tens of thousands of jobs a day, and providing robust and usable resources for scientific groups of all types and sizes. More information can be found at the OSG web site: www.opensciencegrid.org.

The SHiP experiment at CERN

NASA Astrophysics Data System (ADS)

De Lellis, G.; SHiP Collaboration

2017-04-01

The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, which deserve an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment.

The SHiP project at CERN

NASA Astrophysics Data System (ADS)

De Lellis, G.; SHiP Collaboration

2016-07-01

The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry, which deserve an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experimental facility at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using 400 GeV protons is a copious factory of charmed hadrons and could be used to probe the existence of such particles. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment. Resistive Plate Chambers could play a role in the SHiP detector.

The SHiP experiment at CERN

NASA Astrophysics Data System (ADS)

Bonivento, Walter M.

2017-07-01

The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, deserving an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. The neutrino detector can also search for dark matter through its scattering off the electrons. We report the physics potential of the SHiP experiment.

[5 days Cefaclor vs. 10 days amoxicillin/clavulanate in the treatment of childhood streptococcal pharyngitis. Data from a randomized clinical trial].

PubMed

Bottaro, G; Biasci, P; Lo Giudice, M; Mele, G; Montanari, G; Napoleone, E; Santucci, A; Tucci, P L; Fano, M; Biraghi, M G

2012-06-01

The duration of therapy represents a fundamental aspect in the compliance to the therapy of child pathologies, such as pharyngotonsillitis, treated with oral therapy. Although penicillin and amoxicillin are the first choice antibiotics in the case of a child suffering from pharyngotonsillitis with the proven presence of Group A β-hemolytic Streptococcus (GAS), the number of orally administered doses and 10 days of therapy, considerably lower the compliance. An open phase IV randomized multicenter clinical trial was conducted in parallel groups, involving 49 family pediatrician (FP), distributed over the entire national territory, enrolling 435 children suffering from GAS-FT. 210 children received Cefaclor, 50 mg/kg/day, administered twice daily for five days, whilst 213 children received amoxicillin/clavulanate 40 mg/kg/day administered twice daily for 10 days. The results showed percentages of eradication of 88.4% for the Cefaclor group and 94.3% for the amoxicillin/clavulanate group, and a positive clinical judgement of 92.3% for the Cefaclor group and 96.6% for the amoxicillin/clavulanate group. The two arms of the study did not have any significant statistical differences, neither for the eradication, nor for the clinical judgement nor for the reduction of the Milano Score between the beginning and the end of treatment, with a P=0.042 for amoxicillin/clavulanate for eradication. This study confirms that the administration of Cefaclor for five days during GAS-FT has the same efficacy as a 10-day therapy with amoxicillin/clavulanate, with a clearly different compliance.

Mortality rates and risk factors for emergent open repair of abdominal aortic aneurysms in the endovascular era.

PubMed

Pecoraro, Felice; Gloekler, Steffen; Mader, Caecilia E; Roos, Malgorzata; Chaykovska, Lyubov; Veith, Frank J; Cayne, Neal S; Mangialardi, Nicola; Neff, Thomas; Lachat, Mario

2018-03-01

The background of this paper is to report the mortality at 30 and 90 days and at mean follow-up after open abdominal aortic aneurysms (AAA) emergent repair and to identify predictive risk factors for 30- and 90-day mortality. Between 1997 and 2002, 104 patients underwent emergent AAA open surgery. Symptomatic and ruptured AAAs were observed, respectively, in 21 and 79% of cases. Mean patient age was 70 (SD 9.2) years. Mean aneurysm maximal diameter was 7.4 (SD 1.6) cm. Primary endpoints were 30- and 90-day mortality. Significant mortality-related risk factor identification was the secondary endpoint. Open repair trend and its related perioperative mortality with a per-year analysis and a correlation subanalysis to identify predictive mortality factor were performed. Mean follow-up time was 23 (SD 23) months. Overall, 30-day mortality was 30%. Significant mortality-related risk factors were the use of computed tomography (CT) as a preoperative diagnostic tool, AAA rupture, preoperative shock, intraoperative cardiopulmonary resuscitation (CPR), use of aortic balloon occlusion, intraoperative massive blood transfusion (MBT), and development of abdominal compartment syndrome (ACS). Previous abdominal surgery was identified as a protective risk factor. The mortality rate at 90 days was 44%. Significant mortality-related risk factors were AAA rupture, aortocaval fistula, peripheral artery disease (PAD), preoperative shock, CPR, MBT, and ACS. The mortality rate at follow-up was 45%. Correlation analysis showed that MBT, shock, and ACS are the most relevant predictive mortality factor at 30 and 90 days. During the transition period from open to endovascular repair, open repair mortality outcomes remained comparable with other contemporary data despite a selection bias for higher risk patients. MBT, shock, and ACS are the most pronounced predictive mortality risk factors.

33 CFR 100.1304 - Annual Seattle Yacht Club's “Opening Day” Marine Parade.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Annual Seattle Yacht Club's âOpening Dayâ Marine Parade. 100.1304 Section 100.1304 Navigation and Navigable Waters COAST GUARD... Annual Seattle Yacht Club's “Opening Day” Marine Parade. (a) Regulated area. All of Portage Bay, with the...

A new Be star in an open cluster - NGC 6871-8

NASA Technical Reports Server (NTRS)

Grigsby, James A.; Morrison, Nancy D.

1988-01-01

Spectroscopic observations of H-alpha show that star eight in the open cluster NGC 6871 is a previously-undiscovered Be star. The H-alpha profile was observed to vary from clear emission to pure absorption over a period of ten days; later observations over a five-day interval show weak emission along with asymmetries and filling in of the profile.

Open standing castration in Thoroughbred racehorses in Hong Kong: Prevalence and severity of complications 30 days post-castration.

PubMed

Rosanowski, S M; MacEoin, F; Graham, R J T Y; Riggs, C M

2018-05-01

Complications following open standing castration (OSC) in Thoroughbred racehorses are well recognised but variation in their prevalence and severity between populations is not well documented. To describe the prevalence and severity of complications in the 30 days following OSC. A retrospective cohort study of veterinary clinical records relating to horses that underwent OSC between July 2007 and July 2012. Complications were graded on a severity score from N, no complications, to C3, severe complications. Additional data were accessed for each horse including age, import date, racing history, trainer and veterinarian performing the castration. Bacterial culture and antimicrobial sensitivities were performed on a limited number of castration wounds that became infected. In total, 250 horses were castrated in Hong Kong using the OSC technique over the period of the study. Sixty percent (150/250) of horses experienced some type of post-castration complication, with eight horses experiencing a severe (C3) complication requiring intensive veterinary treatment. Scrotal swelling, funiculitis and seroma formation were present in 70.0%, 36.7% and 24.7% of cases respectively. Most horses experiencing complications required wound reopening (87.3%; 131/150), and/or an extended course of first-line antimicrobials and/or nonsteroidal anti-inflammatory drugs (75/150; 50.0%). Eight horses had cultures submitted for bacterial sensitivity, with 17 bacterial isolates grown. In vitro, the bacteria cultured were sensitive to enrofloxacin (76%; 13/17) and ceftiofur (100%; 17/17). Resistance was detected to penicillin, gentamicin, oxytetracycline, metronidazole and trimethoprim-sulfadiazine. Differences in post-castration management cannot be accounted for in this study. Complications following OSC in horses in Hong Kong were common. The majority were mild and were successfully treated using antimicrobials and simple wound management. Given the high rate of complications and

Comparison of endoscopic and open resection of sinonasal squamous cell carcinoma: a propensity score-matched analysis of 652 patients.

PubMed

Kılıç, Suat; Kılıç, Sarah S; Baredes, Soly; Chan Woo Park, Richard; Mahmoud, Omar; Suh, Jeffrey D; Gray, Stacey T; Eloy, Jean Anderson

2018-03-01

The use of endoscopic resection as an alternative to open surgery for sinonasal malignancies has increased in the past 20 years. The National Cancer Database was queried for cases of sinonasal squamous cell carcinoma (SNSCC) without cervical or distant metastases that were treated surgically between 2010 and 2014. They were split into 2 groups based on surgical approach: open or endoscopic. Demographics, facility and insurance type, stage, tumor characteristics, postoperative treatment, 30-day readmission rate, 30- and 90-day mortality, and overall survival (OS) were compared between the 2 groups. Cox proportional hazard analysis was performed. Propensity score matching (PSM) was used to mimic a randomized, controlled trial. A total of 1,483 patients were identified: 353 (23.8%) received endoscopic and 1130 (76.2%) received open surgery. Age, gender, race, geographic region, tumor size, surgical margins, postoperative chemoradiation, and 30-day readmissions did not vary significantly between the 2 groups. Open surgery was more common in academic centers (62.8% vs 54.2%; p = 0.004), less common for tumors of the ethmoid and sphenoid sinus (p < 0.0001), less common for stage IVB tumors, and associated with longer hospital stay (mean, 4.67 days vs 2.50 days; p < 0.0001). Five-year OS (5Y-OS) was not significantly different between the 2 approaches (p = 0.953; open: 5Y-OS, 56.5%; 95% confidence interval, 51.3% to 61.6%; endoscopic: 5Y-OS, 46.0%; 95% confidence interval, 33.2% to 58.8%). In the PSM cohort of 652 patients, there was also no significant difference in OS (p = 0.850). Endoscopic surgery is an effective alternative to open surgery, even after accounting for confounding factors that may favor its use over the open approach. It is also associated with a shorter hospital stay. © 2017 ARS-AAOA, LLC.

Bedside screen for oral cavity structure, salivary flow, and vocal production over the 14days following endotracheal extubation.

PubMed

Chen, Cheryl Chia-Hui; Wu, Kuo-Hsiang; Ku, Shih-Chi; Chan, Ding-Cheng; Lee, Jang-Jaer; Wang, Tyng-Guey; Hsiao, Tzu-Yu

2018-06-01

To describe the sequelae of oral endotracheal intubation by evaluating prevalence rates of structural injury, hyposalivation, and impaired vocal production over 14days following extubation. Consecutive adults (≥20years, N=114) with prolonged (≥48h) endotracheal intubation were enrolled from medical intensive care units at a university hospital. Participants were assessed by trained nurses at 2, 7, and 14days after extubation, using a standardized bedside screening protocol. Within 48-hour postextubation, structural injuries were common, with 51% having restricted mouth opening. Unstimulated salivary flow was reduced in 43%. For vocal production, 51% had inadequate breathing support for phonation, dysphonia was common (94% had hoarseness and 36% showed reduced efficiency of vocal fold closure), and >40% had impaired articulatory precision. By 14days postextubation, recovery was noted in most conditions, but reduced efficiency of vocal fold closure persisted. Restricted mouth opening (39%) and reduced salivary flow (34%) remained highly prevalent. After extubation, restricted mouth opening, reduced salivary flow, and dysphonia were common and prolonged in recovery. Reduced efficiency of vocal cord closure persisted at 14days postextubation. The extent and duration of these sequelae remind clinicians to screen for them up to 2weeks after extubation. Copyright © 2017 Elsevier Inc. All rights reserved.

openSE: a Systems Engineering Framework Particularly Suited to Particle Accelerator Studies and Development Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnal, P.; Féral, B.; Kershaw, K.

Particle accelerator projects share many characteristics with industrial projects. However, experience has shown that best practice of industrial project management is not always well suited to particle accelerator projects. Major differences include the number and complexity of technologies involved, the importance of collaborative work, development phases that can last more than a decade, and the importance of telerobotics and remote handling to address future preventive and corrective maintenance requirements due to induced radioactivity, to cite just a few. The openSE framework it is a systems engineering and project management framework specifically designed for scientific facilities’ systems and equipment studies andmore » development projects. Best practices in project management, in systems and requirements engineering, in telerobotics and remote handling and in radiation safety management were used as sources of inspiration, together with analysis of current practices surveyed at CERN, GSI and ESS.« less

Open versus robotic-assisted transabdominal preperitoneal (R-TAPP) inguinal hernia repair: a multicenter matched analysis of clinical outcomes.

PubMed

Gamagami, R; Dickens, E; Gonzalez, A; D'Amico, L; Richardson, C; Rabaza, J; Kolachalam, R

2018-04-26

To compare the perioperative outcomes of initial, consecutive robotic-assisted transabdominal preperitoneal (R-TAPP) inguinal hernia repair (IHR) cases with consecutive open cases completed by the same surgeons. Multicenter, retrospective, comparative study of perioperative results from open and robotic IHR using standard univariate and multivariate regression analyses for propensity score matched (1:1) cohorts. Seven general surgeons at six institutions contributed 602 consecutive open IHR and 652 consecutive R-TAPP IHR cases. Baseline patient characteristics in the unmatched groups were similar with the exception of previous abdominal surgery and all baseline characteristics were comparable in the matched cohorts. In matched analyses, postoperative complications prior to discharge were comparable. However, from post discharge through 30 days, fewer patients experienced complications in the R-TAPP group than in the open group [4.3% vs 7.7% (p = 0.047)]. The R-TAPP group had no reoperations post discharge through 30 days of follow-up compared with five patients (1.1%) in the open group (p = 0.062), respectively. Multivariate logistic regression analysis which demonstrated patient age > 65 years and the open approach were risk factors for complications within 30 days post discharge in the matched group [age > 65 years: odds ratio (OR) = 3.33 (95% CI 1.89, 5.87; p < 0.0001); open approach: OR = 1.89 (95% CI 1.05, 3.38; p = 0.031)]. In this matched analysis, R-TAPP provides similar postoperative complications prior to discharge and a lower rate of postoperative complications through 30 days compared to open repair. R-TAPP is a promising and reproducible approach, and may facilitate adoption of minimally invasive repairs of inguinal hernias.

Wide Open Spaces: Wikis Ready or Not

ERIC Educational Resources Information Center

Lamb, Brian

2004-01-01

Remember when the Internet was about opening up access to information and breaking down the barriers between content creators and content consumers? Think back to when spam was just a meatlike substance. To those heady days when Timothy Leary was predicting that the PC would be the LSD of the nineties. Before the DMCA. Before eBay. Back when the…

Complications after laparoscopic and open subtotal colectomy for inflammatory colitis: a case-matched comparison.

PubMed

Parnaby, C N; Ramsay, G; Macleod, C S; Hope, N R; Jansen, J O; McAdam, T K

2013-11-01

The aim of this study was to compare the early postoperative outcome of patients undergoing laparoscopic subtotal colectomy with those undergoing open subtotal colectomy for colitis refractory to medical treatment. A retrospective observational study was carried out of patients who underwent subtotal colectomy for refractory colitis, at a single centre, between 2006 and 2012. Patients were matched for age, gender, American Society of Anesthesiology (ASA) grade, urgency of operation and immunosuppressant/modulator treatment. The primary outcome measure was the number of postoperative complications, classified using the Clavien-Dindo scale. Secondary end-points included procedure duration, laparoscopic conversion rates, blood loss, 30-day readmission rates and length of hospital stay. Ninety-six patients were included, 39 of whom had laparoscopic surgery. Thirty-two of these were matched to similar patients who underwent an open procedure. The overall duration of the procedure was longer for laparoscopic surgery than for open surgery (median: 240 vs 150 min, P < 0.005) but estimated blood loss was less (median: 75 vs 400 ml, P < 0.005). In the laparoscopic group, 23 patients experienced 27 complications, and in the open surgery group, 23 patients experienced 30 complications. Most complications were minor (Grade I/II), and the distribution of complications, by grade, was similar between the two groups. There was no statistically significant difference in 30-day readmission rates between the laparoscopic and open groups (five readmissions vs eight readmissions, P = 0.536). Length of hospital stay was 4 days shorter for laparoscopic surgery, but this difference was not statistically significant (median: 7 vs 11 days, P = 0.159). In patients requiring colectomy for acute severe colitis, laparoscopic surgery reduced blood loss but increased operating time and was not associated with a reduction in early postoperative complications, length of hospital stay or readmission

Open Space, Open Education, and Pupil Performance.

ERIC Educational Resources Information Center

Lukasevich, Ann; Gray, Roland F.

1978-01-01

Explores the relationship between instructional style (open and non-open programs), architectural style (open and non-open facilities) and selected cognitive and affective outcomes of third grade pupils. (CM)

Percutaneous biliary drainage using open cell stents for malignant biliary hilar obstruction.

PubMed

Ahn, Sun Jun; Bae, Jae Ik; Han, Tae Sun; Won, Je Hwan; Kim, Ji Dae; Kwack, Kyu-Sung; Lee, Jae Hee; Kim, Young Chul

2012-01-01

To evaluate the feasibility, safety and the effectiveness of the complex assembly of open cell nitinol stents for biliary hilar malignancy. During the 10 month period between January and October 2007, 26 consecutive patients with malignant biliary hilar obstruction underwent percutaneous insertion of open cell design nitinol stents. Four types of stent placement methods were used according to the patients' ductal anatomy of the hilum. We evaluated the technical feasibility of stent placement, complications, patient survival, and the duration of stent patency. Bilobar biliary stent placement was conducted in 26 patients with malignant biliary obstruction-T (n = 9), Y (n = 7), crisscross (n = 6) and multiple intersecting types (n = 4). Primary technical success was obtained in 24 of 26 (93%) patients. The crushing of the 1st stent during insertion of the 2nd stent occurred in two cases. Major complications occurred in 2 of 26 patients (7.7%). One case of active bleeding from hepatic segmental artery and one case of sepsis after procedure occurred. Clinical success was achieved in 21 of 24 (87.5%) patients, who were followed for a mean of 141.5 days (range 25-354 days). The mean primary stent patency period was 191.8 days and the mean patient survival period was 299 days. Applying an open cell stent in the biliary system is feasible, and can be effective, especially in multiple intersecting stent insertions in the hepatic hilum.

[A comparison of laparoscopic versus open repair for the surgical treatment of perforated peptic ulcers].

PubMed

Domínguez-Vega, Gerardo; Pera, Manuel; Ramón, José M; Puig, Sonia; Membrilla, Estela; Sancho, Joan; Grande, Luis

2013-01-01

To analyse the outcomes of laparoscopic versus open repair for perforated peptic ulcers (PPU). All patients undergoing PPU repair between January 2002 and March 2012 were included in the study. Demographic characteristics, operation time, complications, and length of hospital stay were evaluated. Two hundred and twelve patients (median age, 49 years) were included, 60 in the laparoscopic group and 52 in the open group. Patients operated laparoscopically were significantly younger and had a higher consumption of tobacco, alcohol and cannabis. Median acute symptoms time was shorter in the laparoscopic group (6h) compared to the open group (12h; P=.025) Symptoms time was shorter in the laparoscopic group. Median operating time was significantly longer in the laparoscopic group (104.5min vs. 76min, P=.025). The percentage of conversion to open repair was 25%. There was no difference in morbidity between 2 groups, but there were 3 deaths in the open group. Median hospital stay was significantly shorter in patients treated laparoscopically when compared with the open group (6 days vs. 8 days; P=.041). Laparoscopic and open repair are equally safe in the management of PPU. A shorter hospital stay can be achieved in the laparoscopic group. Copyright © 2012 AEC. Published by Elsevier Espana. All rights reserved.

Open Content in Open Context

ERIC Educational Resources Information Center

Kansa, Sarah Whitcher; Kansa, Eric C.

2007-01-01

This article presents the challenges and rewards of sharing research content through a discussion of Open Context, a new open access data publication system for field sciences and museum collections. Open Context is the first data repository of its kind, allowing self-publication of research data, community commentary through tagging, and clear…

Openness, Web 2.0 Technology, and Open Science

ERIC Educational Resources Information Center

Peters, Michael A.

2010-01-01

Open science is a term that is being used in the literature to designate a form of science based on open source models or that utilizes principles of open access, open archiving and open publishing to promote scientific communication. Open science increasingly also refers to open governance and more democratized engagement and control of science…

Follicular development in a 7-day versus 4-day hormone-free interval with an oral contraceptive containing 20 mcg ethinyl estradiol and 1 mg norethindrone acetate.

PubMed

Rible, Radhika D; Taylor, DeShawn; Wilson, Melissa L; Stanczyk, Frank Z; Mishell, Daniel R

2009-03-01

Combined oral contraceptive (COC) formulations with 20 mcg ethinyl estradiol (EE) have a greater incidence of ovarian hormone production and follicular development, which can be managed by shortening the number of hormone-free days per COC cycle. This study evaluates differences in follicular development during a 7-day versus 4-day hormone-free interval in a COC regimen with 20 mcg EE and 1 mg norethindrone acetate. Forty-one healthy women were randomized in an open-label fashion to this formulation in either a 24/4 or a 21/7 day regimen for three cycles. Estradiol, progesterone, follicle-stimulating hormone, luteinizing hormone and inhibin B were measured daily from Cycle 2, Day 21 to Cycle 3, Day 3 and on Day 7 of Cycle 3. Follicular diameter and Hoogland score were calculated on Cycle 2, Days 21, 24 and 28 and Cycle 3, Days 3 and 7. Sixty-six percent of subjects in the 21/7 group and 70% of the subjects in the 24/4 group developed a follicle greater than 10 mm diameter. Ovarian steroid hormone levels, Hoogland scores and bleeding patterns were not statistically significant between the groups. In contrast to prior studies, this analysis suggests no difference in follicle development or bleeding patterns among women receiving a 21/7 or 24/4 regimen of a 20-mcg EE/1-mg norethindrone acetate COC.

The SHiP experiment at CERN SPS

NASA Astrophysics Data System (ADS)

Di Crescenzo, A.; SHiP Collaboration

2016-01-01

SHiP is a new general purpose fixed target facility, whose Technical Proposal has been recently submitted to the CERN SPS Committee. In its initial phase, the 400GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2×1020 pot in 5years. A dedicated detector located downstream of the target, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below a few GeV/c2. The beam dump is also an ideal source of tau neutrinos, the less known particle in the Standard Model. Another dedicated detector, based on the Emulsion Cloud Chamber technology already used in the OPERA experiment, will allow to perform for the first time measurements of the tau neutrino deep inelastic scattering cross section. Tau neutrinos will be distinguished from tau anti-neutrinos, thus providing the first observation of the tau anti-neutrino.

Accelerator controls at CERN: Some converging trends

NASA Astrophysics Data System (ADS)

Kuiper, B.

1990-08-01

CERN's growing services to the high-energy physics community using frozen resources has led to the implementation of "Technical Boards", mandated to assist the management by making recommendations for rationalizations in various technological domains. The Board on Process Control and Electronics for Accelerators, TEBOCO, has emphasized four main lines which might yield economy in resources. First, a common architecture for accelerator controls has been agreed between the three accelerator divisions. Second, a common hardware/software kit has been defined, from which the large majority of future process interfacing may be composed. A support service for this kit is an essential part of the plan. Third, high-level protocols have been developed for standardizing access to process devices. They derive from agreed standard models of the devices and involve a standard control message. This should ease application development and mobility of equipment. Fourth, a common software engineering methodology and a commercial package of application development tools have been adopted. Some rationalization in the field of the man-machine interface and in matters of synchronization is also under way.

Diffractive Higgs boson production at the Fermilab Tevatron and the CERN Large Hadron Collider.

PubMed

Enberg, R; Ingelman, G; Kissavos, A; Tîmneanu, N

2002-08-19

Improved possibilities to find the Higgs boson in diffractive events, having less hadronic activity, depend on whether the cross section is large enough. Based on the soft color interaction models that successfully describe diffractive hard scattering at DESY HERA and the Fermilab Tevatron, we find that only a few diffractive Higgs events may be produced at the Tevatron, but we predict a substantial rate at the CERN Large Hadron Collider.

Various candid views of STS-84 crew after hatch opening

NASA Image and Video Library

1997-05-17

STS084-379-034 (15-24 May 1997) --- Two mission commanders greet and shake hands moments after hatch-opening on docking day, of the Space Shuttle Atlantis and Russia's Mir Space Station. Charles J. Precourt (left), STS-84 commander, and Vasili V. Tsibliyev, Mir-23 commander, along with their respective flight crews went on to spend several days sharing joint activities in Earth-orbit. This is the sixth Atlantis/Mir docking mission.

Anomalous single production of the fourth generation quarks at the CERN LHC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ciftci, R.

Possible anomalous single productions of the fourth standard model generation up and down type quarks at CERN Large Hadron Collider are studied. Namely, pp{yields}u{sub 4}(d{sub 4})X with subsequent u{sub 4}{yields}bW{sup +} process followed by the leptonic decay of the W boson and d{sub 4}{yields}b{gamma} (and its H.c.) decay channel are considered. Signatures of these processes and corresponding standard model backgrounds are discussed in detail. Discovery limits for the quark mass and achievable values of the anomalous coupling strength are determined.

W production at large transverse momentum at the CERN Large Hadron Collider.

PubMed

Gonsalves, Richard J; Kidonakis, Nikolaos; Sabio Vera, Agustín

2005-11-25

We study the production of W bosons at large transverse momentum in pp collisions at the CERN Large Hadron Collider. We calculate the complete next-to-leading order (NLO) corrections to the differential cross section. We find that the NLO corrections provide a large increase to the cross section but, surprisingly, do not reduce the scale dependence relative to leading order (LO). We also calculate next-to-next-to-leading-order (NNLO) soft-gluon corrections and find that, although they are small, they significantly reduce the scale dependence thus providing a more stable result.

Lower limit on dark matter production at the CERN Large Hadron Collider.

PubMed

Feng, Jonathan L; Su, Shufang; Takayama, Fumihiro

2006-04-21

We evaluate the prospects for finding evidence of dark matter production at the CERN Large Hadron Collider. We consider weakly interacting massive particles (WIMPs) and superWIMPs and characterize their properties through model-independent parametrizations. The observed relic density then implies lower bounds on dark matter production rates as functions of a few parameters. For WIMPs, the resulting signal is indistinguishable from background. For superWIMPs, however, this analysis implies significant production of metastable charged particles. For natural parameters, these rates may far exceed Drell-Yan cross sections and yield spectacular signals.

First experience with carbon stripping foils for the 160 MeV H- injection into the CERN PSB

NASA Astrophysics Data System (ADS)

Weterings, Wim; Bracco, Chiara; Jorat, Louise; Noulibos, Remy; van Trappen, Pieter

2018-05-01

160 MeV H- beam will be delivered from the new CERN linear accelerator (Linac4) to the Proton Synchrotron Booster (PSB), using a H- charge-exchange injection system. A 200 µg/cm2 carbon stripping foil will convert H- into protons by stripping off the electrons. The H- charge-exchange injection principle will be used for the first time in the CERN accelerator complex and involves many challenges. In order to gain experience with the foil changing mechanism and the very fragile foils, in 2016, prior to the installation in the PSB, a stripping foil test stand has been installed in the Linac4 transfer line. In addition, parts of the future PSB injection equipment are also temporarily installed in the Linac4 transfer line for tests with a 160 MeV H- commissioning proton beam. This paper describes the foil changing mechanism and control system, summarizes the practical experience of gluing and handling these foils and reports on the first results with beam.

Posture analysis on young women before and after 60 days of -6 degrees head down bed rest (Wise 2005).

PubMed

Viguier, Marion; Dupui, Philippe; Montoya, Richard

2009-02-01

Twenty-four women divided into three groups: control, exercise and nutrition, have been involved in a -6 degrees head down bed rest (HDBR) experiment for 60 days. The objective was to analyse the effects of microgravity on balance function regulation. Group comparisons assessed the efficiency of countermeasures (specific exercises and in particular diet) on the deleterious effects of simulated microgravity. Measurements of orthostatic and dynamic balance were taken 9 and 2 days prior to the experiment, on the first day of getting up, the following day and 4 and 10 days after, under two visual conditions: eyes open and eyes closed. The results confirmed that, as in any other test performed with ordinary subjects, the postural balance performances are better with eyes open than with eyes closed. The static and dynamic postural performances were impaired on the first day of recovery (R0) following HDBR. This impairment lasted up to 4 days after getting up and, afterwards the volunteers recovered their initial performances. The exercise group recovered static postural performances more quickly than the other groups whereas there were no differences in the recovery of the dynamic balance performances.

Retention payoff-based cost per day open regression equations: Application in a user-friendly decision support tool for investment analysis of automated estrus detection technologies.

PubMed

Dolecheck, K A; Heersche, G; Bewley, J M

2016-12-01

Assessing the economic implications of investing in automated estrus detection (AED) technologies can be overwhelming for dairy producers. The objectives of this study were to develop new regression equations for estimating the cost per day open (DO) and to apply the results to create a user-friendly, partial budget, decision support tool for investment analysis of AED technologies. In the resulting decision support tool, the end user can adjust herd-specific inputs regarding general management, current reproductive management strategies, and the proposed AED system. Outputs include expected DO, reproductive cull rate, net present value, and payback period for the proposed AED system. Utility of the decision support tool was demonstrated with an example dairy herd created using data from DairyMetrics (Dairy Records Management Systems, Raleigh, NC), Food and Agricultural Policy Research Institute (Columbia, MO), and published literature. Resulting herd size, rolling herd average milk production, milk price, and feed cost were 323 cows, 10,758kg, $0.41/kg, and $0.20/kg of dry matter, respectively. Automated estrus detection technologies with 2 levels of initial system cost (low: $5,000 vs. high: $10,000), tag price (low: $50 vs. high: $100), and estrus detection rate (low: 60% vs. high: 80%) were compared over a 7-yr investment period. Four scenarios were considered in a demonstration of the investment analysis tool: (1) a herd using 100% visual observation for estrus detection before adopting 100% AED, (2) a herd using 100% visual observation before adopting 75% AED and 25% visual observation, (3) a herd using 100% timed artificial insemination (TAI) before adopting 100% AED, and (4) a herd using 100% TAI before adopting 75% AED and 25% TAI. Net present value in scenarios 1 and 2 was always positive, indicating a positive investment situation. Net present value in scenarios 3 and 4 was always positive in combinations using a $50 tag price, and in scenario 4, the $5

Open Energy Info (OpenEI) (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2010-12-01

The Open Energy Information (OpenEI.org) initiative is a free, open-source, knowledge-sharing platform. OpenEI was created to provide access to data, models, tools, and information that accelerate the transition to clean energy systems through informed decisions.

The Ethical Imperative to Move to a Seven-Day Care Model.

PubMed

Bell, Anthony; McDonald, Fiona; Hobson, Tania

2016-06-01

Whilst the nature of human illness is not determined by time of day or day of week, we currently structure health service delivery around a five-day delivery model. At least one country is endeavouring to develop a systems-based approach to planning a transition from five- to seven-day healthcare delivery models, and some services are independently instituting program reorganization to achieve these ends as research, amongst other things, highlights increased mortality and morbidity for weekend and after-hours admissions to hospitals. In this article, we argue that this issue does not merely raise instrumental concerns but also opens up a normative ethical dimension, recognizing that clinical ethical dilemmas are impacted on and created by systems of care. Using health policy ethics, we critically examine whether our health services, as currently structured, are at odds with ethical obligations for patient care and broader collective goals associated with the provision of publicly funded health services. We conclude by arguing that a critical health policy ethics perspective applying relevant ethical values and principles needs to be included when considering whether and how to transition from five-day to seven-day models for health delivery.

Comparison of treatment costs of laparoscopic and open surgery.

PubMed

Śmigielski, Jacek A; Piskorz, Łukasz; Koptas, Włodzimierz

2015-09-01

Laparoscopy has been a standard procedure in most medical centres providing surgical services for many years. Both the range and number of laparoscopic procedures performed are constantly increasing. Over the last decade, laparoscopic procedures have been successfully applied both in emergency and oncological surgery. However, treatment costs have become a more important factor in choosing between open or laparoscopic procedures. To present the total real costs of open and laparoscopic cholecystectomy, appendectomy and sigmoidectomy. Between 1 May 2010 and 30 March 2015 in the Department of Thoracic Surgery, General and Oncological Surgery, Medical University of Lodz, and in the Department of General Surgery of the Saint John of God Hospital, Lodz, doctors performed 1404 cholecystectomies, 392 appendectomies and 88 sigmoidectomies. A total of 97% of the cholecystectomy procedures were laparoscopic and 3% were open. Similarly, 22% of total appendectomies were laparoscopic and 78% were open, while 9% of sigmoidectomies were laparoscopic and 91% open. The requirement for single-use equipment in laparoscopic procedures increases the expense. However, after adding up all other costs, surprisingly, differences between the costs of laparoscopic and open procedures ranged from 451 PLN/€ 114 for laparoscopic operations to 611 PLN/€ 153 for open operations. Laparoscopic cholecystectomy, considered the standard surgery for treating gallbladder diseases, is cheaper than open cholecystectomy. Laparoscopic appendectomy and sigmoidectomy are safe methods of minimally invasive surgery, slightly more expensive than open operations. Of all the analyzed procedures, one-day laparoscopic cholecystectomy is the most profitable. The costs of both laparoscopic and open sigmoidectomy are greatly underestimated in Poland.

Temperature characterisation of the CLOUD chamber at CERN

NASA Astrophysics Data System (ADS)

Dias, A. M.; Almeida, J.; Kirkby, J.; Mathot, S.; Onnela, A.; Vogel, A.; Ehrhart, S.

2014-12-01

Temperature stability, uniformity and absolute scale inside the CLOUD (Cosmics Leaving OUtdoor Droplets) chamber at CERN are important for experiments on aerosol particle nucleation and ice/liquid cloud formation. In order to measure the air temperature, a comprehensive set of arrays ("strings") of platinum resistance thermometers, thermocouples and optical sensors have been installed inside the 26 m3 chamber. The thermal sensors must meet several challenging design requirements: ultra-clean materials, 0.01 K measurement sensitivity, high absolute precision (<0.1 K), 200 K - 373 K range, ability to operate in high electric fields (20 kV/m), and fast response in air (~1 s) in order to measure rapid changes of temperature during ice/liquid cloud formation in the chamber by adiabatic pressure reductions. This presentation will focus on the design of the thermometer strings and the thermal performance of the chamber during the CLOUD8 and CLOUD9 campaigns, 2013-2014, together with the planned upgrades of the CLOUD thermal system.

Open Thoracotomy and Decortication for Chronic Empyema

PubMed Central

Andrade-Alegre, Rafael; Garisto, Juan D.; Zebede, Salomón

2008-01-01

OBJECTIVES Traditionally, chronic empyema has been treated by thoracotomy and decortication. Some recent reports have claimed similar clinical results for videothoracoscopy, but with less morbidity and mortality than open procedures. Our experience with thoracotomy and decortication is reviewed so that the results of this surgical procedure can be adequately evaluated. MATERIALS AND METHODS From March 1992 to June 2006, 85 patients diagnosed with empyema were treated at Santo Tomás Hospital by the first author. Diagnosis of chronic empyema was based on the duration of signs and symptoms before definitive treatment and imaging findings, such as constriction of the lungs and the thoracic cage. Thirty-three patients fulfilled the criteria for chronic empyema and underwent open thoracotomy and decortication. RESULTS Twenty-seven patients (81.8 %) were male and the average age of the study group was 34 years. The etiology was pneumonia in 26 patients (78.8%) and trauma in 7 (21.2%). The duration of symptoms and signs before definitive treatment averaged 37 days. All patients had chronic empyema, as confirmed by imaging studies and operative findings. Surgery lasted an average of 139 min. There were 3 (9%) complications with no mortality. The post-operative length of stay averaged 10 days. There were no recurrences of empyema. CONCLUSIONS Open thoracotomy and decortication can be achieved with low morbidity and mortality. Long-term functional results are especially promising. We suggest that the validation of other surgical approaches should be based on comparative, prospective and controlled studies. PMID:19061002

Surgical treatment of distal tibia fractures: open versus MIPO.

PubMed

Gülabi, Deniz; Bekler, Halil İbrahim; Sağlam, Fevzi; Taşdemir, Zeki; Çeçen, Gültekin Sıtkı; Elmalı, Nurzat

2016-01-01

Treatment of the distal tibial fractures are challenging due to the limited soft tissue, subcutaneous location and poor vascularity. In this control-matched study, it was aimed to compare the traditional open reduction and internal fixation with minimal invasive plating (MIPO). We hypothesized that superior results may be achieved with MIPO technique. 22 patients treated with traditional open reduction and internal fixation were matched with 22 patients treated with closed reduction and MIPO on the basis of age (±3), gender, and fracture pattern (AO classification). Evaluation was assed according to the wound problems, the American Orthopaedic Foot and Ankle surgery (AOFAS) scoring, radiological union, malunion, delayed union, hospitalisation time, time from injury to surgery, and operation time. There was no significant difference in the distribution of AO/OTA classification, age, gender, AOFAS score, time from injury to operation, follow-up, bone union time, delayed union, malunion and infection (p>0.05). The operation time was significantly longer in the open group than in the MIPO group: 69.59±7.21 min. for the ORIF, and 61.14±5.61 for the MIPO group (p<0.01).The hospitalisation time was significantly longer in the open group than in the MIPO group: 7.64±4.71 days for the MIPO, and 10.18±4.32 days for the ORIF group (p<0.05). MIPO technique can be beneficial for the treatment of distal tibia AO/OTA A and B type fractures with reduced hospital stay, cost-effectiveness, and infection rate.

Long Term Outcomes of Laparoscopic and Open Modified Lich-Gregoir Reimplantation in Adults: A multicentric comparative study.

PubMed

Atar, Arda; Eksi, Mithat; Güler, Ahmet Faysal; Tuncer, Murat; Akkas, Fatih; Tugcu, Volkan

2017-01-01

Obstructive ureteral pathologies in adult patients are most commonly due to ureteral strictures and secondary to surgical interventions. In this study, we aimed to compare open and laparoscopic modified Lich-Gregoir ureteral reimplantation with regards to outcomes in benign ureteral pathologies in adult patients. Between December 2008 and December 2014, 32 open cases and 29 laparoscopic cases were performed as per the data retrieved from surgical databases. All laparoscopic procedures were performed in Bakirkoy Dr. Sadi Konuk Training and Research Hospital(BEAH) and all open ureteral reimplantation procedures in Kartal Dr Lutfi Kirdar Training and Research Hospital(KEAH) and Okmeydani Training and Research Hospital(OEAH). The mean operation time was significantly lower in the group of patients operated with open group (142.5 minutes versus 188.9 minutes; P< 0.0001). The mean duration of follow-up was longer in the laparoscopy group (31 versus 28 months; p< 0.0001). The mean amount of operation associated blood loss was significantly lower in patients operated laparoscopically (93.7 mL versus 214 mL; P< 0.0001). The mean VAS score obtained six hours after surgery was 6.6 ± 0.8 in open group, and 5.8 ± 0.7 in laparoscopic group (p=0.0004). The mean VAS scores measured at post-operative day 1 was 4.5 ± 0.7 in open group and 3.7 ± 0.9 in laparoscopy group. Time required to achieve the pre-operative capability of daily activities was significantly longer in open group (15 ± 1.4 days vs 11 ± 1.4 days; p< 0.0001). Despite open techniques provide shorter operation time and laparoscopic techniques require long learning curve, we think that laparoscopic techniques are superior to open ones since that they provide a better post-operative comfort and are better tolerated in terms of complications.

Improved infiltration series for studying stomatal opening as illustrated with coffee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alvim, P.deT.; Havis, J.R.

1956-01-01

Very satisfactory results have been obtained in estimation of the degree of stomatal opening of several plant species by using infiltration series prepared with Nujol mineral oil diluted with xylol, kerosene, n-dodecane, n-tetradecane, or Bayol-D. All of these materials, except Nujol, infiltrate the leaves when the stomata are only slightly open. Nujol does not penetrate even wide open stomata, except for plants with particularly large stomata. The results with coffee plants show that leaves exposed to direct sunlight decreased their stomatal aperture during periods of strong illumination in the middle of the day (more than about 8000 fc). 9 references,more » 2 figures.« less

Integrating new Storage Technologies into EOS

NASA Astrophysics Data System (ADS)

Peters, Andreas J.; van der Ster, Dan C.; Rocha, Joaquim; Lensing, Paul

2015-12-01

The EOS[1] storage software was designed to cover CERN disk-only storage use cases in the medium-term trading scalability against latency. To cover and prepare for long-term requirements the CERN IT data and storage services group (DSS) is actively conducting R&D and open source contributions to experiment with a next generation storage software based on CEPH[3] and ethernet enabled disk drives. CEPH provides a scale-out object storage system RADOS and additionally various optional high-level services like S3 gateway, RADOS block devices and a POSIX compliant file system CephFS. The acquisition of CEPH by Redhat underlines the promising role of CEPH as the open source storage platform of the future. CERN IT is running a CEPH service in the context of OpenStack on a moderate scale of 1 PB replicated storage. Building a 100+PB storage system based on CEPH will require software and hardware tuning. It is of capital importance to demonstrate the feasibility and possibly iron out bottlenecks and blocking issues beforehand. The main idea behind this R&D is to leverage and contribute to existing building blocks in the CEPH storage stack and implement a few CERN specific requirements in a thin, customisable storage layer. A second research topic is the integration of ethernet enabled disks. This paper introduces various ongoing open source developments, their status and applicability.

Live Webcasts from CERN and ESO for European Science and Technology Week

NASA Astrophysics Data System (ADS)

2002-10-01

Visit http://www.cern.ch/sci-tech on 7 - 8 November to find out what modern Europeans can't live without. Seven of Europe's leading Research Organizations [1] are presenting three live Webcasts from CERN in a joint outreach programme for the European Science and Technology Week . The aim of Sci-Tech... couldn't be without it! is to show how today's society couldn't be without cutting-edge scientific research. See also ESO Press Release 05/02. Northern Europeans can't imagine their households without ovens, whereas Southern Europeans identify the refrigerator as the most essential household appliance. In the area of communications, cars and motorbikes are clearly the technologies of choice in Italy, but are regarded as less important in countries like Norway and Germany. For entertainment, the personal computer is a clear winner as the device is considered most essential by all Europeans, followed by the TV and the Internet. This hit parade of technological marvels is the result of a phone and online survey conducted by the Sci-Tech... couldn't be without it! team for this year's European Science and Technology Week on 4-10 November. The technologies Europeans could not be without, form the starting point of three entertaining and informative Webcast shows in Italian (Thursday 7 November at 10:00 CET), French (Thursday 7 November at 15:00 CET) and English (Friday 8 November at 15:00 CET), broadcast live on the Internet from a studio at CERN. During these Webcasts scientists from the seven research Organizations and their industrial partners Sun Microsystems, Siemens, L'Oreal and Luminex will engage - from the CERN studio or from remote locations through teleconference links - an audience of Internauts all over the world. The public will be taken inside their most popular gadgets to discover the science that made them possible and how vital fundamental research has been in the creation of modern technology. Fundamental science will be brought as close as possible to

Faculty Perception of Openness and Attitude to Open Sharing at the Indian National Open University

ERIC Educational Resources Information Center

Panda, Santosh; Santosh, Sujata

2017-01-01

In the past decade, the educational scenario world over has significantly been impacted by open access and open education movements. The philosophy of openness and sharing forms the cornerstone of the open education movement. The distance education approaches, together with open educational resources (OER) and massive open online courses (MOOCs),…

The CERN-EU high-energy Reference Field (CERF) facility: applications and latest developments

NASA Astrophysics Data System (ADS)

Silari, Marco; Pozzi, Fabio

2017-09-01

The CERF facility at CERN provides an almost unique high-energy workplace reference radiation field for the calibration and test of radiation protection instrumentation employed at high-energy accelerator facilities and for aircraft and space dosimetry. This paper describes the main features of the facility and supplies a non-exhaustive list of recent (as of 2005) applications for which CERF is used. Upgrade work started in 2015 to provide the scientific and industrial communities with a state-of-the-art reference facility is also discussed.

STS-72 Flight Day 2

NASA Technical Reports Server (NTRS)

1996-01-01

On this second day of the STS-72 mission, the flight crew, Cmdr. Brian Duffy, Pilot Brent W. Jett, and Mission Specialists Leroy Chiao, Daniel T. Barry, Winston E. Scott, and Koichi Wakata (NASDA), awakened to music from the motion picture 'Star Wars.' The crew performed a systems checkout, prepared for the retrieval of the Japanese Space Flyer Unit (SFU), tested the spacesuits for the EVA, and activated some of the secondary experiments. An in-orbit news interview was conducted with the crew via satellite downlinking. Questions asked ranged from the logistics of the mission to the avoidance procedures the Endeavour Orbiter performed to miss hitting the inactive Air Force satellite, nicknamed 'Misty' (MSTI). Earth views included cloud cover, several storm systems, and various land masses with several views of the shuttle's open cargo bay in the foreground.

Surgical injury: comparing open surgery and laparoscopy by markers of tissue damage.

PubMed

Máca, Jan; Peteja, Matúš; Reimer, Petr; Jor, Ondřej; Šeděnková, Věra; Panáčková, Lucie; Ihnát, Peter; Burda, Michal; Ševčík, Pavel

2018-01-01

Major abdominal surgery (MAS) is high-risk intervention usually accompanied by tissue injury leading to a release of signaling danger molecules called alarmins. This study evaluates the surgical injury caused by two fundamental types of gastrointestinal surgical procedures (open surgery and laparoscopy) in relation to the inflammation elicited by alarmins. Patients undergoing MAS were divided into a mixed laparoscopy group (LPS) and an open surgery group (LPT). Serum levels of alarmins (S100A8, S100A12, HMGB1, and HSP70) and biomarkers (leukocytes, C-reactive protein [CRP], and interleukin-6 [IL-6]) were analyzed between the groups. The secondary objectives were to compare LPT and LPS cancer subgroups and to find the relationship between procedure and outcome (intensive care unit length of stay [ICU-LOS] and hospital length of stay [H-LOS]). A total of 82 patients were analyzed. No significant difference was found in alarmin levels between the mixed LPS and LPT groups. IL-6 was higher in the LPS group on day 2 ( p =0.03) and day 3 ( p =0.04). Significantly higher S100A8 protein levels on day 1 ( p =0.02) and day 2 ( p =0.01) and higher S100A12 protein levels on day 2 ( p =0.03) were obtained in the LPS cancer subgroup. ICU-LOS and H-LOS were longer in the LPS cancer subgroup. The degree of surgical injury elicited by open MAS as reflected by alarmins is similar to that of laparoscopic procedures. Nevertheless, an early biomarker of inflammation (IL-6) was higher in the laparoscopy group, suggesting a greater inflammatory response. Moreover, the levels of S100A8 and S100A12 were higher with a longer ICU-LOS and H-LOS in the LPS cancer subgroup.

Surgical injury: comparing open surgery and laparoscopy by markers of tissue damage

PubMed Central

Máca, Jan; Peteja, Matúš; Reimer, Petr; Jor, Ondřej; Šeděnková, Věra; Panáčková, Lucie; Ihnát, Peter; Burda, Michal; Ševčík, Pavel

2018-01-01

Background Major abdominal surgery (MAS) is high-risk intervention usually accompanied by tissue injury leading to a release of signaling danger molecules called alarmins. This study evaluates the surgical injury caused by two fundamental types of gastrointestinal surgical procedures (open surgery and laparoscopy) in relation to the inflammation elicited by alarmins. Patients and methods Patients undergoing MAS were divided into a mixed laparoscopy group (LPS) and an open surgery group (LPT). Serum levels of alarmins (S100A8, S100A12, HMGB1, and HSP70) and biomarkers (leukocytes, C-reactive protein [CRP], and interleukin-6 [IL-6]) were analyzed between the groups. The secondary objectives were to compare LPT and LPS cancer subgroups and to find the relationship between procedure and outcome (intensive care unit length of stay [ICU-LOS] and hospital length of stay [H-LOS]). Results A total of 82 patients were analyzed. No significant difference was found in alarmin levels between the mixed LPS and LPT groups. IL-6 was higher in the LPS group on day 2 (p=0.03) and day 3 (p=0.04). Significantly higher S100A8 protein levels on day 1 (p=0.02) and day 2 (p=0.01) and higher S100A12 protein levels on day 2 (p=0.03) were obtained in the LPS cancer subgroup. ICU-LOS and H-LOS were longer in the LPS cancer subgroup. Conclusion The degree of surgical injury elicited by open MAS as reflected by alarmins is similar to that of laparoscopic procedures. Nevertheless, an early biomarker of inflammation (IL-6) was higher in the laparoscopy group, suggesting a greater inflammatory response. Moreover, the levels of S100A8 and S100A12 were higher with a longer ICU-LOS and H-LOS in the LPS cancer subgroup. PMID:29881282

A Randomized Trial Comparing Stapled Rectal Mucosectomy Versus Open and Semiclosed Hemorrhoidectomy.

PubMed

Ripetti, Valter; La Vaccara, Vincenzo; Greco, Santi; Arullani, Augusto

2015-11-01

Different results have been reported concerning the postoperative outcomes of different surgical approaches for hemorrhoids. We aimed to determine the postoperative outcome following 3 main surgical techniques. A prospective, randomized trial was designed with 180 patients in 3 arms of 60 patients each. The study was conducted from April 1999 to January 2007 at the University Hospital "Campus Bio-Medico di Roma." All of the patients who were referred for hemorrhoid surgery were enrolled according to inclusion and exclusion criteria (ISRCTN12040297). Treatments according to the open, semiclosed, and stapled techniques were compared. Sample size was calculated to determine a difference in terms of the intensity of postoperative pain at the first week and the days required for return to work activity. After 1 week, patients who underwent semiclosed hemorrhoidectomy reported significantly less pain (p < 0.01) and a significant decrease in analgesic intake from the third postoperative day (p < 0.01) than after the other 2 techniques. The patients resumed work ≈11 days after semiclosed and stapled techniques (11.8 and 11.6 days), which was earlier compared with 21.3 days in the open group (p < 0.05). The high number of patients excluded might be considered a limitation of the study, but our selection criteria including patients living within 50 km of the hospital allowed for a low rate (9.4%) of patients lost to follow-up. This study found an earlier resumption of work and less pain in patients who underwent the stapled and semiclosed procedures rather than open, which was associated with more complications, particularly because of a higher rate of stenosis (see Video, Supplemental Digital Content 1, http://links.lww.com/DCR/A196).

A Good Beginning Makes a Good Market: The Effect of Different Market Opening Structures on Market Quality

PubMed Central

Hinterleitner, Gernot; Leopold-Wildburger, Ulrike

2015-01-01

This paper deals with the market structure at the opening of the trading day and its influence on subsequent trading. We compare a single continuous double auction and two complement markets with different call auction designs as opening mechanisms in a unified experimental framework. The call auctions differ with respect to their levels of transparency. We find that a call auction not only improves market efficiency and liquidity at the beginning of the trading day when compared to the stand-alone continuous double auction, but also causes positive spillover effects on subsequent trading. Concerning the design of the opening call auction, we find no significant differences between the transparent and nontransparent specification with respect to opening prices and liquidity. In the course of subsequent continuous trading, however, market quality is slightly higher after a nontransparent call auction. PMID:26351653

A Good Beginning Makes a Good Market: The Effect of Different Market Opening Structures on Market Quality.

PubMed

Hinterleitner, Gernot; Leopold-Wildburger, Ulrike; Mestel, Roland; Palan, Stefan

2015-01-01

This paper deals with the market structure at the opening of the trading day and its influence on subsequent trading. We compare a single continuous double auction and two complement markets with different call auction designs as opening mechanisms in a unified experimental framework. The call auctions differ with respect to their levels of transparency. We find that a call auction not only improves market efficiency and liquidity at the beginning of the trading day when compared to the stand-alone continuous double auction, but also causes positive spillover effects on subsequent trading. Concerning the design of the opening call auction, we find no significant differences between the transparent and nontransparent specification with respect to opening prices and liquidity. In the course of subsequent continuous trading, however, market quality is slightly higher after a nontransparent call auction.

Routine pelvic drainage not required after open or robotic radical prostatectomy.

PubMed

Sharma, Satish; Kim, Hyung Lae; Mohler, James L

2007-02-01

To determine whether radical prostatectomy requires urinary drainage. All patients with clinically localized prostate cancer had complete clinical and pathologic information recorded prospectively in a database. The criteria for omission of pelvic drainage were successful bladder neck preservation; urethrovesical anastomosis performed using 6 interrupted sutures in open cases or 12 continuous sutures in robotic cases; and a watertight urethrovesical anastomosis on irrigation. Most patients were discharged on the first or second postoperative day. The catheters were removed routinely on postoperative day 9. A pelvic drain was not placed in 78% of 325 consecutive patients. A drain was omitted in 73% of 225 open cases and 90% of 100 robotic cases. The recovery of continence and the complication rates were similar between the two groups with and without pelvic drainage. Complications occurred in 11% of the group with pelvic drainage and 6% in the group without pelvic drainage. In the past 2 years, 17 of 126 patients required pelvic drainage. The frequency of complications in robotic versus open procedures was similar (chi-square test, P >0.05). Pelvic drainage may be omitted after radical prostatectomy when the urethrovesical anastomosis is performed well. Drainage omission could contribute to shortened hospital stays and reduced costs, without added complications. These benefits can be extended safely to patients undergoing open or robotic radical prostatectomy.

Learning about World War II at the D-Day Beaches of Normandy

ERIC Educational Resources Information Center

O'Hara, Lynne M.

2013-01-01

In the winter of 2011, this author was working late in her classroom at Central Bucks High School West in Doylestown, Pennsylvania, when she opened an email offering a summer institute where 15 teachers would walk the D-Day beaches in Normandy, France. The catch--each teacher had to bring one high school student. The Albert Small Student/Teacher…

Agent-based Large-Scale Emergency Evacuation Using Real-Time Open Government Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lu, Wei; Liu, Cheng; Bhaduri, Budhendra L

The open government initiatives have provided tremendous data resources for the transportation system and emergency services in urban areas. This paper proposes a traffic simulation framework using high temporal resolution demographic data and real time open government data for evacuation planning and operation. A comparison study using real-world data in Seattle, Washington is conducted to evaluate the framework accuracy and evacuation efficiency. The successful simulations of selected area prove the concept to take advantage open government data, open source data, and high resolution demographic data in emergency management domain. There are two aspects of parameters considered in this study: usermore » equilibrium (UE) conditions of traffic assignment model (simple Non-UE vs. iterative UE) and data temporal resolution (Daytime vs. Nighttime). Evacuation arrival rate, average travel time, and computation time are adopted as Measure of Effectiveness (MOE) for evacuation performance analysis. The temporal resolution of demographic data has significant impacts on urban transportation dynamics during evacuation scenarios. Better evacuation performance estimation can be approached by integrating both Non-UE and UE scenarios. The new framework shows flexibility in implementing different evacuation strategies and accuracy in evacuation performance. The use of this framework can be explored to day-to-day traffic assignment to support daily traffic operations.« less

OpenFresco | OpenFresco

Science.gov Websites

Skip to content HOME NEWS USERS OpenFrescoExpress OpenFresco Examples & Tools Feedback staff and research students learning about hybrid simulation and starting to use this experimental the Pacific Earthquake Engineering Research Center (PEER) and others. Search Search for: Search Menu

Routine laparoscopic repair of primary unilateral inguinal hernias--a viable alternative in the day surgery unit?

PubMed

Duff, M; Mofidi, R; Nixon, S J

2007-08-01

In September 2004 the NICE institute revised its guidelines on the management of primary inguinal hernias to include laparoscopic repair of unilateral hernias. While published trials have confirmed the equal efficacy of the two approaches, it is not clear what impact a switch to laparoscopic repairs would have on resources and patient throughput in a Day Surgery Unit. All elective hernia repairs performed in a one-year period were considered. Data were obtained from operation notes, discharge summaries and out-patient records. Operating times are routinely documented in theatre. Of the 351 operations studied, 150 were performed laparoscopically predominantly by an extraperitoneal (TEP)approach. Six required conversion to an open procedure. There was no significant difference in operating times, total theatre time or recovery room times between the two groups (51 min, 75 min and 34 min for the laparoscopic group and 53 min, 74 min and 31 min for the open repair group). Among the laparoscopic repair group there were 48 bilateral hernias and 20 recurrent hernias while 190 of the 201 open repairs were for primary unilateral hernias. Rates of overnight stay and immediate complications were similar between the groups though haematoma was more common following open repair (7 vs 2). There is no difference in theatre times, immediate complication rates or rates of overnight stay between open and laparoscopic repair of inguinal hernia. Routine laparoscopic repair of primary unilateral inguinal hernia is a viable alternative within the Day Surgery Unit.

Re-Invigorating Openness at The Open University: The Role of Open Educational Resources

ERIC Educational Resources Information Center

Gourley, Brenda; Lane, Andy

2009-01-01

This paper describes the internal motivations and external drivers that led The Open University UK to enter the field of Open Educational Resources through its institution-wide OpenLearn initiative (www.open.ac.uk/openlearn). It also describes some of the emerging evidence of the impacts inside and outside the university. Through the rapid…

Orbital Analysis of Two Triple Systems in the Open Cluster NGC 2516

NASA Astrophysics Data System (ADS)

Veramendi, M. E.; González, J. F.

2010-12-01

We report the discovery of two hierarchical triple systems in the open cluster NGC 2516. Both systems are double-lined spectroscopic binaries whose center-of-mass velocity varies in a time scale of a few years. The system BDA 19 consists of an eccentric spectroscopic binary with a period of 8.7 days and a third body orbiting with a period of about 3300 days. The close pair in the triple BDA 2 has an orbital period of 11.2 days and contains a HgMn star.

Developing Open Education Literacies with Practicing K-12 Teachers

ERIC Educational Resources Information Center

Kimmons, Royce M.

2014-01-01

This study seeks to understand how to use formal learning activities to effectively support the development of open education literacies among K-12 teachers. Considering pre-and post-surveys from K-12 teachers (n = 80) who participated in a three-day institute, this study considers whether participants entered institutes with false confidence or…

Comparable perioperative mortality outcomes in younger patients undergoing elective open and endovascular abdominal aortic aneurysm repair.

PubMed

Liang, Nathan L; Reitz, Katherine M; Makaroun, Michel S; Malas, Mahmoud B; Tzeng, Edith

2018-05-01

Evidence for benefit of endovascular aneurysm repair (EVAR) over open surgical repair for de novo infrarenal abdominal aortic aneurysms (AAAs) in younger patients remains conflicting because of heterogeneous study populations and small sample sizes. The objective of this study was to compare perioperative and short-term outcomes for EVAR and open surgery in younger patients using a large national disease and procedure-specific data set. We identified patients 65 years of age or younger undergoing first-time elective EVAR or open AAA repair from the Vascular Quality Initiative (2003-2014). We excluded patients with pararenal or thoracoabdominal aneurysms, those medically unfit for open repair, and those undergoing EVAR for isolated iliac aneurysms. Clinical and procedural characteristics were balanced using inverse propensity of treatment weighting. A supplemental analysis extended the study to those younger than 70 years. We identified 2641 patients, 73% (n = 1928) EVAR and 27% (n = 713) open repair. The median age was 62 years (interquartile range, 59-64 years), and 13% were female. The median follow-up time was 401 days (interquartile range, 357-459 days). Unadjusted perioperative survival was 99.6% overall (open repair, 99.1%; EVAR, 99.8%; P < .001), with 97.4% 1-year survival overall (open repair, 97.3%; EVAR, 97.4%; P = .9). Unadjusted reintervention rates were five (open repair) and seven (EVAR) reinterventions per 100 person-years (P = .8). After propensity weighting, the absolute incidence of perioperative mortality was <1% in both groups (open repair, 0.9%, EVAR, 0.2%; P < .001), and complication rates were low. Propensity-weighted survival (hazard ratio, 0.88; 95% confidence interval, 0.56-1.38; P = .6) and reintervention rates (open repair, 6; EVAR, 8; reinterventions per 100 person-years; P = .8) did not differ between the two interventions. The analysis of those younger than 70 years showed similar results. In this study of younger

Open Source, Openness, and Higher Education

ERIC Educational Resources Information Center

Wiley, David

2006-01-01

In this article David Wiley provides an overview of how the general expansion of open source software has affected the world of education in particular. In doing so, Wiley not only addresses the development of open source software applications for teachers and administrators, he also discusses how the fundamental philosophy of the open source…

Day case management of sickle pain: 3 years experience in a UK sickle cell unit.

PubMed

Wright, J; Bareford, D; Wright, C; Augustine, G; Olley, K; Musamadi, L; Dhanda, C; Knight, C

2004-09-01

A day centre was established to determine whether an alternative approach to the management of uncomplicated sickle pain would improve the quality of care and reduce hospital admissions in patients with sickle cell disease. Since the centre opened there has been a 43% decrease in hospital admissions and 49% decrease in occupied bed days. In the third year, 84% of patients treated for severe sickle pain were managed without the need for hospital admission. A centre offering day case management of painful crisis reduced unnecessary hospital admissions for uncomplicated pain. This approach is safe and cost-effective.

Randomized clinical trial of laparoscopic versus open repair of the perforated peptic ulcer: the LAMA Trial.

PubMed

Bertleff, Mariëtta J O E; Halm, Jens A; Bemelman, Willem A; van der Ham, Arie C; van der Harst, Erwin; Oei, Hok I; Smulders, J F; Steyerberg, E W; Lange, Johan F

2009-07-01

Laparoscopic surgery has become popular during the last decade, mainly because it is associated with fewer postoperative complications than the conventional open approach. It remains unclear, however, if this benefit is observed after laparoscopic correction of perforated peptic ulcer (PPU). The goal of the present study was to evaluate whether laparoscopic closure of a PPU is as safe as conventional open correction. The study was based on a randomized controlled trial in which nine medical centers from the Netherlands participated. A total of 109 patients with symptoms of PPU and evidence of air under the diaphragm were scheduled to receive a PPU repair. After exclusion of 8 patients during the operation, outcomes were analyzed for laparotomy (n = 49) and for the laparoscopic procedure (n = 52). Operating time in the laparoscopy group was significantly longer than in the open group (75 min versus 50 min). Differences regarding postoperative dosage of opiates and the visual analog scale (VAS) for pain scoring system were in favor of the laparoscopic procedure. The VAS score on postoperative days 1, 3, and 7 was significant lower (P < 0.05) in the laparoscopic group. Complications were equally distributed. Hospital stay was also comparable: 6.5 days in the laparoscopic group versus 8.0 days in the open group (P = 0.235). Laparoscopic repair of PPU is a safe procedure compared with open repair. The results considering postoperative pain favor the laparoscopic procedure.

Open core control software for surgical robots.

PubMed

Arata, Jumpei; Kozuka, Hiroaki; Kim, Hyung Wook; Takesue, Naoyuki; Vladimirov, B; Sakaguchi, Masamichi; Tokuda, Junichi; Hata, Nobuhiko; Chinzei, Kiyoyuki; Fujimoto, Hideo

2010-05-01

In these days, patients and doctors in operation room are surrounded by many medical devices as resulting from recent advancement of medical technology. However, these cutting-edge medical devices are working independently and not collaborating with each other, even though the collaborations between these devices such as navigation systems and medical imaging devices are becoming very important for accomplishing complex surgical tasks (such as a tumor removal procedure while checking the tumor location in neurosurgery). On the other hand, several surgical robots have been commercialized, and are becoming common. However, these surgical robots are not open for collaborations with external medical devices in these days. A cutting-edge "intelligent surgical robot" will be possible in collaborating with surgical robots, various kinds of sensors, navigation system and so on. On the other hand, most of the academic software developments for surgical robots are "home-made" in their research institutions and not open to the public. Therefore, open source control software for surgical robots can be beneficial in this field. From these perspectives, we developed Open Core Control software for surgical robots to overcome these challenges. In general, control softwares have hardware dependencies based on actuators, sensors and various kinds of internal devices. Therefore, these control softwares cannot be used on different types of robots without modifications. However, the structure of the Open Core Control software can be reused for various types of robots by abstracting hardware dependent parts. In addition, network connectivity is crucial for collaboration between advanced medical devices. The OpenIGTLink is adopted in Interface class which plays a role to communicate with external medical devices. At the same time, it is essential to maintain the stable operation within the asynchronous data transactions through network. In the Open Core Control software, several

Open core control software for surgical robots

PubMed Central

Kozuka, Hiroaki; Kim, Hyung Wook; Takesue, Naoyuki; Vladimirov, B.; Sakaguchi, Masamichi; Tokuda, Junichi; Hata, Nobuhiko; Chinzei, Kiyoyuki; Fujimoto, Hideo

2010-01-01

Object In these days, patients and doctors in operation room are surrounded by many medical devices as resulting from recent advancement of medical technology. However, these cutting-edge medical devices are working independently and not collaborating with each other, even though the collaborations between these devices such as navigation systems and medical imaging devices are becoming very important for accomplishing complex surgical tasks (such as a tumor removal procedure while checking the tumor location in neurosurgery). On the other hand, several surgical robots have been commercialized, and are becoming common. However, these surgical robots are not open for collaborations with external medical devices in these days. A cutting-edge “intelligent surgical robot” will be possible in collaborating with surgical robots, various kinds of sensors, navigation system and so on. On the other hand, most of the academic software developments for surgical robots are “home-made” in their research institutions and not open to the public. Therefore, open source control software for surgical robots can be beneficial in this field. From these perspectives, we developed Open Core Control software for surgical robots to overcome these challenges. Materials and methods In general, control softwares have hardware dependencies based on actuators, sensors and various kinds of internal devices. Therefore, these control softwares cannot be used on different types of robots without modifications. However, the structure of the Open Core Control software can be reused for various types of robots by abstracting hardware dependent parts. In addition, network connectivity is crucial for collaboration between advanced medical devices. The OpenIGTLink is adopted in Interface class which plays a role to communicate with external medical devices. At the same time, it is essential to maintain the stable operation within the asynchronous data transactions through network. In the Open

The beam and detector of the NA62 experiment at CERN

NASA Astrophysics Data System (ADS)

Cortina Gil, E.; Martín Albarrán, E.; Minucci, E.; Nüssle, G.; Padolski, S.; Petrov, P.; Szilasi, N.; Velghe, B.; Georgiev, G.; Kozhuharov, V.; Litov, L.; Husek, T.; Kampf, K.; Zamkovsky, M.; Aliberti, R.; Geib, K. H.; Khoriauli, G.; Kleinknecht, K.; Kunze, J.; Lomidze, D.; Marchevski, R.; Peruzzo, L.; Vormstein, M.; Wanke, R.; Winhart, A.; Bolognesi, M.; Carassiti, V.; Chiozzi, S.; Cotta Ramusino, A.; Gianoli, A.; Malaguti, R.; Dalpiaz, P.; Fiorini, M.; Gamberini, E.; Neri, I.; Norton, A.; Petrucci, F.; Statera, M.; Wahl, H.; Bucci, F.; Ciaranfi, R.; Lenti, M.; Maletta, F.; Volpe, R.; Bizzeti, A.; Cassese, A.; Iacopini, E.; Antonelli, A.; Capitolo, E.; Capoccia, C.; Cecchetti, A.; Corradi, G.; Fascianelli, V.; Gonnella, F.; Lamanna, G.; Lenci, R.; Mannocchi, G.; Martellotti, S.; Moulson, M.; Paglia, C.; Raggi, M.; Russo, V.; Santoni, M.; Spadaro, T.; Tagnani, D.; Valeri, S.; Vassilieva, T.; Cassese, F.; Roscilli, L.; Ambrosino, F.; Capussela, T.; Di Filippo, D.; Massarotti, P.; Mirra, M.; Napolitano, M.; Saracino, G.; Barbanera, M.; Cenci, P.; Checcucci, B.; Duk, V.; Farnesini, L.; Gersabeck, E.; Lupi, M.; Papi, A.; Pepe, M.; Piccini, M.; Scolieri, G.; Aisa, D.; Anzivino, G.; Bizzarri, M.; Campeggi, C.; Imbergamo, E.; Piluso, A.; Santoni, C.; Berretta, L.; Bianucci, S.; Burato, A.; Cerri, C.; Fantechi, R.; Galeotti, S.; Magazzu', G.; Minuti, M.; Orsini, A.; Petragnani, G.; Pontisso, L.; Raffaelli, F.; Spinella, F.; Collazuol, G.; Mannelli, I.; Avanzini, C.; Costantini, F.; Di Lella, L.; Doble, N.; Giorgi, M.; Giudici, S.; Pedreschi, E.; Piandani, R.; Pierazzini, G.; Pinzino, J.; Sozzi, M.; Zaccarelli, L.; Biagioni, A.; Leonardi, E.; Lonardo, A.; Valente, P.; Vicini, P.; D'Agostini, G.; Ammendola, R.; Bonaiuto, V.; De Simone, N.; Federici, L.; Fucci, A.; Paoluzzi, G.; Salamon, A.; Salina, G.; Sargeni, F.; Biino, C.; Dellacasa, G.; Garbolino, S.; Marchetto, F.; Martoiu, S.; Mazza, G.; Rivetti, A.; Arcidiacono, R.; Bloch-Devaux, B.; Boretto, M.; Iacobuzio, L.; Menichetti, E.; Soldi, D.; Engelfried, J.; Estrada-Tristan, N.; Bragadireanu, A. M.; Hutanu, O. E.; Azorskiy, N.; Elsha, V.; Enik, T.; Falaleev, V.; Glonti, L.; Gusakov, Y.; Kakurin, S.; Kekelidze, V.; Kilchakovskaya, S.; Kislov, E.; Kolesnikov, A.; Madigozhin, D.; Misheva, M.; Movchan, S.; Polenkevich, I.; Potrebenikov, Y.; Samsonov, V.; Shkarovskiy, S.; Sotnikov, S.; Tarasova, L.; Zaytseva, M.; Zinchenko, A.; Bolotov, V.; Fedotov, S.; Gushin, E.; Khotjantsev, A.; Khudyakov, A.; Kleimenova, A.; Kudenko, Yu.; Shaikhiev, A.; Gorin, A.; Kholodenko, S.; Kurshetsov, V.; Obraztsov, V.; Ostankov, A.; Rykalin, V.; Semenov, V.; Sugonyaev, V.; Yushchenko, O.; Bician, L.; Blazek, T.; Cerny, V.; Koval, M.; Lietava, R.; Aglieri Rinella, G.; Arroyo Garcia, J.; Balev, S.; Battistin, M.; Bendotti, J.; Bergsma, F.; Bonacini, S.; Butin, F.; Ceccucci, A.; Chiggiato, P.; Danielsson, H.; Degrange, J.; Dixon, N.; Döbrich, B.; Farthouat, P.; Gatignon, L.; Golonka, P.; Girod, S.; Goncalves Martins De Oliveira, A.; Guida, R.; Hahn, F.; Harrouch, E.; Hatch, M.; Jarron, P.; Jamet, O.; Jenninger, B.; Kaplon, J.; Kluge, A.; Lehmann-Miotto, G.; Lichard, P.; Maire, G.; Mapelli, A.; Morant, J.; Morel, M.; Noël, J.; Noy, M.; Palladino, V.; Pardons, A.; Perez-Gomez, F.; Perktold, L.; Perrin-Terrin, M.; Petagna, P.; Poltorak, K.; Riedler, P.; Romagnoli, G.; Ruggiero, G.; Rutter, T.; Rouet, J.; Ryjov, V.; Saputi, A.; Schneider, T.; Stefanini, G.; Theis, C.; Tiuraniemi, S.; Vareia Rodriguez, F.; Venditti, S.; Vergain, M.; Vincke, H.; Wertelaers, P.; Brunetti, M. B.; Edwards, S.; Goudzovski, E.; Hallgren, B.; Krivda, M.; Lazzeroni, C.; Lurkin, N.; Munday, D.; Newson, F.; Parkinson, C.; Pyatt, S.; Romano, A.; Serghi, X.; Sergi, A.; Staley, R.; Sturgess, A.; Heath, H.; Page, R.; Angelucci, B.; Britton, D.; Protopopescu, D.; Skillicorn, I.; Cooke, P.; Dainton, J. B.; Fry, J. R.; Fulton, L.; Hutchcroft, D.; Jones, E.; Jones, T.; Massri, K.; Maurice, E.; McCormick, K.; Sutcliffe, P.; Wrona, B.; Conovaloff, A.; Cooper, P.; Coward, D.; Rubin, P.; Winston, R.

2017-05-01

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K+ → π+ ν bar nu decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. The beam line and detector components are described together with their early performance obtained from 2014 and 2015 data.

A cost comparison of laparoscopic and open colon surgery in a publicly funded academic institution.

PubMed

Hardy, Krista M; Kwong, Josephine; Pitzul, Kristen B; Vergis, Ashley S; Jackson, Timothy D; Urbach, David R; Okrainec, Allan

2014-04-01

The objective of this study was to compare the total hospital cost of laparoscopic (lap) and open colon surgery at a publicly funded academic institution. Patients undergoing elective laparoscopic or open colon surgery for all indications at the University Health Network, Toronto, Canada, from April 2004 to March 2009 were included. Patient demographic, operative, and outcome data were reviewed retrospectively. Hospital costs were determined from the Ontario Case Costing Initiative, adjusted for inflation, and compared using the Mann-Whitney U test. Linear regression was used to analyze the relationship between length of stay and total hospital cost. There were 391 elective colon resections (223 lap/168 open, 15.4 % conversion). There was no difference in median age, gender, or Charlson score. Body mass index was slightly higher for laparoscopic surgery (27.5/25.9 lap/open; p = 0.008), while the American Society of Anesthesiologists score was slightly higher for open surgery. Median operative time was greater for laparoscopic surgery (224/196 min, lap/open; p = 0.001). There was no difference in complication rates (21.6/22.5 % lap/open; p = 0.900), reoperations (5.8/6.5 % lap/open; p = 0.833) or 30-day readmissions (7.6/12.5 % lap/open; p = 0.122). Number of emergency room visits was greater with open surgery (12.6/20.8 % lap/open; p = 0.037). Operative cost was higher for laparoscopic surgery ($4,171.37/3,489.29 lap/open; p = 0.001), while total hospital cost was significantly reduced ($9,600.22/12,721.41 lap/open; p = 0.001). Median length of stay was shorter for laparoscopic surgery (5/7 days lap/open; p = 0.000), and this correlated directly with hospital cost. Laparoscopic colon surgery is associated with increased operative costs but significantly lower total hospital costs. The cost savings is related, in part, to reduced length of stay with laparoscopic surgery.

Web Based Monitoring in the CMS Experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Badgett, William; Borrello, Laura; Chakaberia, Irakli

2014-09-03

The Compact Muon Solenoid (CMS) is a large and complex general purpose experiment at the CERN Large Hadron Collider (LHC), built and maintained by many collaborators from around the world. Efficient operation of the detector requires widespread and timely access to a broad range of monitoring and status information. To this end the Web Based Monitoring (WBM) system was developed to present data to users located anywhere from many underlying heterogeneous sources, from real time messaging systems to relational databases. This system provides the power to combine and correlate data in both graphical and tabular formats of interest to themore » experimenters, including data such as beam conditions, luminosity, trigger rates, detector conditions, and many others, allowing for flexibility on the user side. This paper describes the WBM system architecture and describes how the system was used during the first major data taking run of the LHC.« less

Characteristics of an open-cut coal mine fire pollution event

NASA Astrophysics Data System (ADS)

Reisen, Fabienne; Gillett, Rob; Choi, Jason; Fisher, Gavin; Torre, Paul

2017-02-01

On 9 February 2014, embers from a nearby grass/shrub fire spotted into an unused part of the Hazelwood open-cut brown coal mine located in the Latrobe Valley of Victoria, Australia and started a fire that spread rapidly and extensively throughout the mine under strong south-westerly winds and burned over a period of 45 days. The close proximity of the town to the coal mine and the low buoyancy of the smoke plume led to the accumulation of dense smoke levels in the township of Morwell (population of 14,000) particularly under south-westerly winds. A maximum daily PM2.5 concentration of 731 μg m-3 and 8-h CO concentration of 33 ppm were measured at Morwell South, the closest residential area located approximately 500 m from the mine. These concentrations were significantly higher than national air quality standards. Air quality monitoring undertaken in the Latrobe Valley showed that smoke from the Hazelwood mine fire affected a wide area, with particle air quality standards also exceeded in Traralgon (population of 25,000) located approximately 13 km from the mine. Pollutant levels were significantly elevated in February, decreased in March once the fire abated and then returned to background levels once the fire was declared safe at the end of March. While the smoke extent was of a similar order of magnitude to other major air pollution events worldwide, a closer look at emissions ratios showed that the open combustion of lignite brown coal in the Hazelwood mine was different to open combustion of biomass, including peat. It suggested that the dominant combustion process was char combustion. While particle and carbon monoxide monitoring started approximately 4 days after the fire commenced when smoke levels were very high, targeted monitoring of air toxics only began on 26 February (17 days after the fire) when smoke levels had subsided. Limited research on emission factors from open-cut coal mine fires make it difficult to assess the likely concentrations of air

The effects of Tarantula cubensis venom on open wound healing in rats.

PubMed

Gul Satar, N Y; Cangul, I T; Topal, A; Kurt, H; Ipek, V; Onel, G I

2017-02-02

The aim of this study was to evaluate the clinical and histopathological effects of two different dosages of alcohol extract of Tarantula cubensis (Theranekron) on open wounds. A total of 24 Sprague-Dawley rats were randomly divided into Tarantula cubensis extract (TCE1, n=8) 1/10 diluted, TCE (TCE2, n=8), and (3) vehicle-control (0.2 ml of 96 % ethanol, n=8) groups. Experimental full-thickness 1 x 1cm wounds were created on dorsum skin. TCE or vehicle were given systemically by subcutaneous injections on postoperative days 1 and 4. Wound planimetry and procurement of biopsies was performed on days 4, 8, 12 and 16. The mean non-epithelialised wound area in the vehicle-control group was significantly larger than in the TCE1 group on days 4, 8, 12 and 16, and in the TCE2 group on days 8, 12 and 16 (p<0.05). The mean percentage of wound contraction was significantly higher in the TCE1 and TCE2 groups than in the vehicle control group on days 8, 12 and 16 (p<0.05). Histopathologically, wound healing was characterised by a significant decrease in the neutrophil counts and a significant increase in neovascularisation; neither were effected by TCE. Our results suggest that alcohol extract of Tarantula cubensis accelerates epithelialisation and, thus, has beneficial effects on open wound healing in rats.

Lead ions and Coulomb’s Law at the LHC (CERN)

NASA Astrophysics Data System (ADS)

Cid-Vidal, Xabier; Cid, Ramon

2018-03-01

Although for most of the time the Large Hadron Collider (LHC) at CERN collides protons, for around one month every year lead ions are collided, to expand the diversity of the LHC research programme. Furthermore, in an effort not originally foreseen, proton-lead collisions are also taking place, with results of high interest to the physics community. All the large experiments of the LHC have now joined the heavy-ion programme, including the LHCb experiment, which was not at first expected to be part of it. The aim of this article is to introduce a few simple physical calculations relating to some electrical phenomena that occur when lead-ion bunches are running in the LHC, using Coulomb’s Law, to be taken to the secondary school classroom to help students understand some important physical concepts.

Shielding design for the front end of the CERN SPL.

PubMed

Magistris, Matteo; Silari, Marco; Vincke, Helmut

2005-01-01

CERN is designing a 2.2-GeV Superconducting Proton Linac (SPL) with a beam power of 4 MW, to be used for the production of a neutrino superbeam. The SPL front end will initially accelerate 2 x 10(14) negative hydrogen ions per second up to an energy of 120 MeV. The FLUKA Monte Carlo code was employed for shielding design. The proposed shielding is a combined iron-concrete structure, which also takes into consideration the required RF wave-guide ducts and access labyrinths to the machine. Two beam-loss scenarios were investigated: (1) constant beam loss of 1 Wm(-1) over the whole accelerator length and (2) full beam loss occurring at various locations. A comparison with results based on simplified approaches is also presented.

Protective mechanical ventilation during general anesthesia for open abdominal surgery improves postoperative pulmonary function.

PubMed

Severgnini, Paolo; Selmo, Gabriele; Lanza, Christian; Chiesa, Alessandro; Frigerio, Alice; Bacuzzi, Alessandro; Dionigi, Gianlorenzo; Novario, Raffaele; Gregoretti, Cesare; de Abreu, Marcelo Gama; Schultz, Marcus J; Jaber, Samir; Futier, Emmanuel; Chiaranda, Maurizio; Pelosi, Paolo

2013-06-01

The impact of intraoperative ventilation on postoperative pulmonary complications is not defined. The authors aimed at determining the effectiveness of protective mechanical ventilation during open abdominal surgery on a modified Clinical Pulmonary Infection Score as primary outcome and postoperative pulmonary function. Prospective randomized, open-label, clinical trial performed in 56 patients scheduled to undergo elective open abdominal surgery lasting more than 2 h. Patients were assigned by envelopes to mechanical ventilation with tidal volume of 9 ml/kg ideal body weight and zero-positive end-expiratory pressure (standard ventilation strategy) or tidal volumes of 7 ml/kg ideal body weight, 10 cm H2O positive end-expiratory pressure, and recruitment maneuvers (protective ventilation strategy). Modified Clinical Pulmonary Infection Score, gas exchange, and pulmonary functional tests were measured preoperatively, as well as at days 1, 3, and 5 after surgery. Patients ventilated protectively showed better pulmonary functional tests up to day 5, fewer alterations on chest x-ray up to day 3 and higher arterial oxygenation in air at days 1, 3, and 5 (mmHg; mean ± SD): 77.1 ± 13.0 versus 64.9 ± 11.3 (P = 0.0006), 80.5 ± 10.1 versus 69.7 ± 9.3 (P = 0.0002), and 82.1 ± 10.7 versus 78.5 ± 21.7 (P = 0.44) respectively. The modified Clinical Pulmonary Infection Score was lower in the protective ventilation strategy at days 1 and 3. The percentage of patients in hospital at day 28 after surgery was not different between groups (7 vs. 15% respectively, P = 0.42). A protective ventilation strategy during abdominal surgery lasting more than 2 h improved respiratory function and reduced the modified Clinical Pulmonary Infection Score without affecting length of hospital stay.

Open Data, Open Source and Open Standards in chemistry: The Blue Obelisk five years on

PubMed Central

2011-01-01

Background The Blue Obelisk movement was established in 2005 as a response to the lack of Open Data, Open Standards and Open Source (ODOSOS) in chemistry. It aims to make it easier to carry out chemistry research by promoting interoperability between chemistry software, encouraging cooperation between Open Source developers, and developing community resources and Open Standards. Results This contribution looks back on the work carried out by the Blue Obelisk in the past 5 years and surveys progress and remaining challenges in the areas of Open Data, Open Standards, and Open Source in chemistry. Conclusions We show that the Blue Obelisk has been very successful in bringing together researchers and developers with common interests in ODOSOS, leading to development of many useful resources freely available to the chemistry community. PMID:21999342

With Dante in Hell on 9/11: "That Day We Read No Further"

ERIC Educational Resources Information Center

Rosenstein, Roy

2015-01-01

In this article, Roy Rosenstein shares the events that occurred during his first day of teaching the Dante and Medieval Culture course in the fall semester of 2001 at the American University of Paris (AUP). On, September 11, 2001, immediately following Rosenstein's opening statement of "Welcome to hell," the class was alerted to the…

A Day in the Life of a Psychiatry Resident: A Pilot Qualitative Analysis

ERIC Educational Resources Information Center

Hilty, Donald M.; Maynes, Sonya M.; Kellner, Maria; Clark, Marilyn S.; Bourgeois, James A.; Servis, Mark E.

2005-01-01

Objective: The topic "A Day in the Life of a Psychiatry Resident" is an opportunity to explore residents' experiences to inform the delivery of education. Methods: An open-ended, qualitative approach was used in a pilot project to explore contemporary residents' experiences with education, similar to a patient-centered model of health care.…

Primary Care Providers' Opening of Time-Sensitive Alerts Sent to Commercial Electronic Health Record InBaskets.

PubMed

Cutrona, Sarah L; Fouayzi, Hassan; Burns, Laura; Sadasivam, Rajani S; Mazor, Kathleen M; Gurwitz, Jerry H; Garber, Lawrence; Sundaresan, Devi; Houston, Thomas K; Field, Terry S

2017-11-01

Time-sensitive alerts are among the many types of clinical notifications delivered to physicians' secure InBaskets within commercial electronic health records (EHRs). A delayed alert review can impact patient safety and compromise care. To characterize factors associated with opening of non-interruptive time-sensitive alerts delivered into primary care provider (PCP) InBaskets. We analyzed data for 799 automated alerts. Alerts highlighted actionable medication concerns for older patients post-hospital discharge (2010-2011). These were study-generated alerts sent 3 days post-discharge to InBaskets for 75 PCPs across a multisite healthcare system, and represent a subset of all urgent InBasket notifications. Using EHR access and audit logs to track alert opening, we performed bivariate and multivariate analyses calculating associations between patient characteristics, provider characteristics, contextual factors at the time of alert delivery (number of InBasket notifications, weekday), and alert opening within 24 h. At the time of alert delivery, the PCPs had a median of 69 InBasket notifications and had received a median of 379.8 notifications (IQR 295.0, 492.0) over the prior 7 days. Of the 799 alerts, 47.1% were opened within 24 h. Patients with longer hospital stays (>4 days) were marginally more likely to have alerts opened (OR 1.48 [95% CI 1.00-2.19]). Alerts delivered to PCPs whose InBaskets had a higher number of notifications at the time of alert delivery were significantly less likely to be opened within 24 h (top quartile >157 notifications: OR 0.34 [95% CI 0.18-0.61]; reference bottom quartile ≤42). Alerts delivered on Saturdays were also less likely to be opened within 24 h (OR 0.18 [CI 0.08-0.39]). The number of total InBasket notifications and weekend delivery may impact the opening of time-sensitive EHR alerts. Further study is needed to support safe and effective approaches to care team management of InBasket notifications.

When Every Day Is Professional Development Day

ERIC Educational Resources Information Center

Tienken, Christopher H.; Stonaker, Lew

2007-01-01

In the Monroe Township (New Jersey) Public Schools, teachers' learning occurs daily, not just on one day in October and February. Central office and school-level administrators foster job-embedded teacher growth. Every day is a professional development day in the district, but that has not always been so. How did the district become a system with…

Long Term Outcomes of Laparoscopic and Open Modified Lich-Gregoir Reimplantation in Adults: A multicentric comparative study

PubMed Central

Atar, Arda; Eksi, Mithat; Güler, Ahmet Faysal; Tuncer, Murat; Akkas, Fatih; Tugcu, Volkan

2017-01-01

Background & Objective: Obstructive ureteral pathologies in adult patients are most commonly due to ureteral strictures and secondary to surgical interventions. In this study, we aimed to compare open and laparoscopic modified Lich-Gregoir ureteral reimplantation with regards to outcomes in benign ureteral pathologies in adult patients. Methods: Between December 2008 and December 2014, 32 open cases and 29 laparoscopic cases were performed as per the data retrieved from surgical databases. All laparoscopic procedures were performed in Bakirkoy Dr. Sadi Konuk Training and Research Hospital(BEAH) and all open ureteral reimplantation procedures in Kartal Dr Lutfi Kirdar Training and Research Hospital(KEAH) and Okmeydani Training and Research Hospital(OEAH). Results: The mean operation time was significantly lower in the group of patients operated with open group (142.5 minutes versus 188.9 minutes; P< 0.0001). The mean duration of follow-up was longer in the laparoscopy group (31 versus 28 months; p< 0.0001). The mean amount of operation associated blood loss was significantly lower in patients operated laparoscopically (93.7 mL versus 214 mL; P< 0.0001). The mean VAS score obtained six hours after surgery was 6.6 ± 0.8 in open group, and 5.8 ± 0.7 in laparoscopic group (p=0.0004). The mean VAS scores measured at post-operative day 1 was 4.5 ± 0.7 in open group and 3.7 ± 0.9 in laparoscopy group. Time required to achieve the pre-operative capability of daily activities was significantly longer in open group (15 ± 1.4 days vs 11 ± 1.4 days; p< 0.0001). Conclusion: Despite open techniques provide shorter operation time and laparoscopic techniques require long learning curve, we think that laparoscopic techniques are superior to open ones since that they provide a better post-operative comfort and are better tolerated in terms of complications. PMID:29067040

Is Conventional Open Repair for Abdominal Aortic Aneurysm Feasible in Nonagenarians?

PubMed

Uehara, Kyokun; Matsuda, Hitoshi; Inoue, Yosuke; Omura, Atsushi; Seike, Yoshimasa; Sasaki, Hiroaki; Kobayashi, Junjiro

2017-09-25

Background : Although endovascular repair for abdominal aortic aneurysm has been found to be beneficial in very elderly patients, some patients have contraindications to this procedure. For nonagenarians, the results of open repair remain unclear. The purpose of this study was to compare the outcomes of open vs. endovascular repair for abdominal aortic aneurysm in nonagenarian patients. Methods and Results : Fourteen patients undergoing open surgical repair and 24 undergoing endovascular repair for abdominal aortic aneurysm were evaluated. There was no significant difference in early mortality between the open and endovascular groups (0% vs. 4.1%, p=0.16). The open repair group required much longer hospital stays (26.4 vs. 10.6 days, respectively, p=0.003). Finally, 12 patients (86%) undergoing open repair vs. 21 (88%) undergoing endovascular repair returned home (p=0.49). During a mean follow-up period of 23.4±23.5 months, cumulative estimated 1- and 3-year survival rates were 90.0% and 48.0%, respectively in the open repair group and 90.6% and 54.9%, respectively in the endovascular repair group (p=0.51). Conclusion : Although endovascular repair for abdominal aortic aneurysm was superior in terms of recovery, the results of conventional open repair were acceptable even in nonagenarian patients. Open repair remains an alternative for patients with contraindications to endovascular repair.

Mainstreaming Open Textbooks: Educator Perspectives on the Impact of OpenStax College Open Textbooks

ERIC Educational Resources Information Center

Pitt, Rebecca

2015-01-01

This paper presents the results of collaborative research between open textbook provider OpenStax College (OSC) and the OER Research Hub (OERRH), a Hewlett funded mixed methods open research project examining the impact of open educational resources (OER) on learning and teaching. The paper focuses primarily on the results of two surveys that were…

STS-82 Flight Day 01 Highlights

NASA Technical Reports Server (NTRS)

1997-01-01

The first day of the STS-82 mission begins with the crew, Commander Kenneth D. Bowersox, Pilot Scott J. Horowitz, Payload Commander Mark C. Lee, and Mission Specialists Gregory J. Harbaugh, Steven L. Smith, Joseph R. Tanner, and Steven A. Hawley performing pre-launch activities such as eating the traditional breakfast, being suited up, and riding out to the launch pad. Also, included are various panoramic views of the shuttle on the pad. The crew is readied in the 'white room' for their mission. After the closing of the hatch, and arm retraction, launch activities are shown including the countdown, engine ignition, launch, shuttle roll maneuver, and then the separation of the Solid Rocket Boosters (SRB) from the shuttle. Once in orbit the cargo bay doors are seen opening.

An alternative model to distribute VO software to WLCG sites based on CernVM-FS: a prototype at PIC Tier1

NASA Astrophysics Data System (ADS)

Lanciotti, E.; Merino, G.; Bria, A.; Blomer, J.

2011-12-01

In a distributed computing model as WLCG the software of experiment specific application software has to be efficiently distributed to any site of the Grid. Application software is currently installed in a shared area of the site visible for all Worker Nodes (WNs) of the site through some protocol (NFS, AFS or other). The software is installed at the site by jobs which run on a privileged node of the computing farm where the shared area is mounted in write mode. This model presents several drawbacks which cause a non-negligible rate of job failure. An alternative model for software distribution based on the CERN Virtual Machine File System (CernVM-FS) has been tried at PIC, the Spanish Tierl site of WLCG. The test bed used and the results are presented in this paper.

O8.10A MODEL FOR RESEARCH INITIATIVES FOR RARE CANCERS: THE COLLABORATIVE EPENDYMOMA RESEARCH NETWORK (CERN)

PubMed Central

Armstrong, T.S.; Aldape, K.; Gajjar, A.; Haynes, C.; Hirakawa, D.; Gilbertson, R.; Gilbert, M.R.

2014-01-01

Ependymoma represents less than 5% of adult central nervous system (CNS) tumors and a higher percentage of pediatric CNS tumors, but it remains an orphan disease. The majority of the laboratory-based research and clinical trials have been conducted in the pediatric setting, a reflection of the relative incidence and funding opportunities. CERN, created in 2006, was designed to establish a collaborative effort between laboratory and clinical research and pediatric and adult investigators. The organization of CERN is based on integration and collaboration among five projects. Project 1 contains the clinical trials network encompassing both adult and pediatric centers. This group has completed 2 clinical trials with more underway. Project 2 is focused on molecular classification of human ependymoma tumor tissues and also contains the tumor repository which has now collected over 600 fully clinically annotated CNS ependymomas from adults and children. Project 3 is focused on drug discovery utilizing robust laboratory models of ependymoma to perform high throughput screening of drug libraries, then taking promising agents through extensive preclinical testing including monitoring of drug delivery to tumor using state of the art microdialysis. Project 4 contains the basic research efforts evaluating the molecular pathogenesis of ependymoma and has successfully translated these findings by generating the first mouse models of ependymoma that are employed in preclinical drug development in Project 3. Project 5 studies patient outcomes, including the incorporation of these measures in the clinical trials. This project also contains an online Ependymoma Outcomes survey, collecting data on the consequences of the disease and its treatment. These projects have been highly successful and collaborative. For example, the serial measurement of symptom burden (Project 5) has greatly contributed to the evaluation of treatment efficacy of a clinical trial (Project 1) and

A Curriculum of Open Possibilities: A New Zealand Kindergarten Teacher's View of Professional Practice

ERIC Educational Resources Information Center

Dalli, Carmen

2011-01-01

Thematic analysis of a continuous video record of a day in the life of a New Zealand kindergarten teacher, and of a narrative reconstruction of the day during a follow-up interview, yielded a view of early childhood professional practice as focused on a "curriculum of open possibilities". This paper discusses elements of the teacher's…

Optimising the Active Muon Shield for the SHiP Experiment at CERN

NASA Astrophysics Data System (ADS)

Baranov, A.; Burnaev, E.; Derkach, D.; Filatov, A.; Klyuchnikov, N.; Lantwin, O.; Ratnikov, F.; Ustyuzhanin, A.; Zaitsev, A.

2017-12-01

The SHiP experiment is designed to search for very weakly interacting particles beyond the Standard Model which are produced in a 400 GeV/c proton beam dump at the CERN SPS. The critical challenge for this experiment is to keep the Standard Model background level negligible. In the beam dump, around 1011 muons will be produced per second. The muon rate in the spectrometer has to be reduced by at least four orders of magnitude to avoid muoninduced backgrounds. It is demonstrated that new improved active muon shield may be used to magnetically deflect the muons out of the acceptance of the spectrometer.

Development of radiation tolerant components for the Quench Protection System at CERN

NASA Astrophysics Data System (ADS)

Bitterling, O.; Denz, R.; Steckert, J.; Uznanski, S.

2016-01-01

This paper describes the results of irradiation campaigns with the high resolution Analog to Digital Converter (ADC) ADS1281. This ADC will be used as part of a revised quench detection circuit for the 600 A corrector magnets at the CERN Large Hadron Collider (LHC) . To verify the radiation tolerance of the ADC an irradiation campaign using a proton beam, applying doses up to 3,4 kGy was conducted. The resulting data and an analysis of the found failure modes is discussed in this paper. Several mitigation measures are described that allow to reduce the error rate to levels acceptable for operation as part of the LHC QPS.

Early Outcomes following Endovascular, Open Surgical, and Hybrid Revascularization for Lower Extremity Acute Limb Ischemia.

PubMed

Davis, Frank M; Albright, Jeremy; Gallagher, Katherine A; Gurm, Hitinder S; Koenig, Gerald C; Schreiber, Theodore; Grossman, P Michael; Henke, Peter K

2018-03-05

Acute limb ischemia (ALI) of the lower extremity is a potentially devastating condition that requires urgent and definitive management. This challenging scenario is often treated with endovascular, open surgical, or hybrid revascularization (HyR) in an urgent basis, but the comparative effects of such therapies remain poorly defined. The purpose of this study was to compare the outcomes of endovascular, open surgical, and HyR for ALI in the contemporary era. A large statewide cardiovascular consortium of 45 hospitals was queried for patients between January 2012 and June 2015 who underwent an endovascular, open surgical, or HyR for ALI deemed at high risk of limb loss if not treated within 24 hr (Rutherford class IIA or IIB). A propensity score weighted analysis was performed controlling for demographics, medical history, and procedure type for patients. The primary outcomes were 30-day morbidity and mortality. A total of 1,480 patients underwent endovascular revascularization (ER; n = 818), open surgical revascularization (OSR; n = 195), or hybrid revascularization (HyR; n = 467) for ALI. The mean age was similar across revascularization technique with an increased predominance of male gender in open surgery cohort. Comorbidities for all groups were consistent with peripheral arterial disease. The most common endovascular procedures were angioplasty (93%) and thrombolysis (49.8%), whereas the most common surgical revascularization was femoral to popliteal bypass (32.8%), femoral to tibial bypass (28.2%), and thrombectomy (19.0%); ER as compared with OSR and HyR procedures was associated with less transfusion (OSR versus ER, odds ratio [OR] 2.7; HyR versus ER, OR 2.8; P < 0.001) and major amputation (OSR versus ER, OR 3.4; HyR versus ER, OR 4.0; P < 0.001) within 30 days of intervention. There was no difference in 30-day freedom from reintervention, myocardial infarction (MI), or mortality. Among patients requiring urgent revascularization for Rutherford

Sharing Lessons-Learned on Effective Open Data, Open-Source Practices from OpenAQ, a Global Open Air Quality Community.

NASA Astrophysics Data System (ADS)

Hasenkopf, C. A.

2017-12-01

Increasingly, open data, open-source projects are unearthing rich datasets and tools, previously impossible for more traditional avenues to generate. These projects are possible, in part, because of the emergence of online collaborative and code-sharing tools, decreasing costs of cloud-based services to fetch, store, and serve data, and increasing interest of individuals to contribute their time and skills to 'open projects.' While such projects have generated palpable enthusiasm from many sectors, many of these projects face uncharted paths for sustainability, visibility, and acceptance. Our project, OpenAQ, is an example of an open-source, open data community that is currently forging its own uncharted path. OpenAQ is an open air quality data platform that aggregates and universally formats government and research-grade air quality data from 50 countries across the world. To date, we make available more than 76 million air quality (PM2.5, PM10, SO2, NO2, O3, CO and black carbon) data points through an open Application Programming Interface (API) and a user-customizable download interface at https://openaq.org. The goal of the platform is to enable an ecosystem of users to advance air pollution efforts from science to policy to the private sector. The platform is also an open-source project (https://github.com/openaq) and has only been made possible through the coding and data contributions of individuals around the world. In our first two years of existence, we have seen requests for data to our API skyrocket to more than 6 million datapoints per month, and use-cases as varied as ingesting data aggregated from our system into real-time models of wildfires to building open-source statistical packages (e.g. ropenaq and py-openaq) on top of the platform to creating public-friendly apps and chatbots. We will share a whirl-wind trip through our evolution and the many lessons learned so far related to platform structure, community engagement, organizational model type

Day-to-day mastery and self-efficacy changes during a smoking quit attempt: Two studies.

PubMed

Warner, Lisa M; Stadler, Gertraud; Lüscher, Janina; Knoll, Nina; Ochsner, Sibylle; Hornung, Rainer; Scholz, Urte

2018-05-01

assumptions on how self-efficacy is built formulated by Bandura two decades ago, there is only little empirical evidence on the origins of self-efficacy. The open research questions for these two studies were whether mastery experiences (experiencing success with the new behavior) and vicarious experiences (seeing others succeed) facilitate the smoking cessation process, whether mastery experiences and self-efficacy affect one another reciprocally and whether intimate partners serve as role models for each other. What does this study add? Mastery experiences and self-efficacy are mutually depended on a day-to-day basis within the smoking cessation process. Effects of mastery experiences fade rapidly, indicating that constant successes are needed to keep up self-efficacy. Dual-smoker couples show similar changes in a contagious way - if mastery experiences increase in one person, mastery experiences increase in the partner; if self-efficacy increases in one person, self-efficacy increases in the partner, too. No support for vicarious experiences (mastery experiences in one person affecting self-efficacy in the partner and vice versa) as sources of self-efficacy in the quitting process was found. © 2018 The British Psychological Society.

Recent results from the NA48 experiment at CERN

NASA Astrophysics Data System (ADS)

Shkarovskiy, Sergey; NA48/2 Collaboration

2017-12-01

The NA48/2 experiment presents a final result of the charged kaon semileptonic decays form factors measurement based on 4.28 million Ke3+/- and 2.91 million K{μ3}+/- selected decays collected in 2004. The result is competetive with other measurements in K{μ3}+/- mode and has a smallest uncertainty for Ke3+/- , that leads to the most precise combined Kl3+/- result and allows to reduce the form factor uncertainty of |VUS |. The NA48/2 experiment at CERN collected a very large sample of charged kaon decays into multiple final states. From this data sample we have reconstructed about 1663 events of the very rare decay K ± → μ ± νe + e - over almost negligible background in the region with m(e + e -) above 140 MeV, which is of great interest in Chiral Perturbation Theory. We present the mee spectrum and a model-independent measurement of the decay rate for this region.

Research on data from the ATLAS experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Purohit, Milind V.

2015-07-31

In this report senior investigator Prof. Milind V. Purohit describes research done with data from the ATLAS experiment at CERN. This includes preparing papers on the performance of the CSC detector, searches for SUSY using a new modern ''big data'' technique, and a search for supersymmetry (SUSY) using the "zero leptons razor" (0LRaz) technique. The prediction of the W=Z+jets background processes by the ATLAS simulation prior to the fit is found to be overestimated in the phase space of interest. In all new signal regions presented in this analysis the number of events observed is consistent with the post-fit SMmore » expectations. Assuming R-parity conservation, the limit on the gluino mass exceeds 1150 GeV at 95% confidence level, for an LSP mass smaller than 100 GeV. Other USC personnel who participated in this project during the period of this grant were a graduate student, Anton Kravchenko.« less

Open surgery versus endovascular approach in treatment of extracranial carotid artery aneurysms.

PubMed

Ni, Leng; Weng, Huiling; Pu, Zuo; Zheng, Yuehong; Liu, Bao; Ye, Wei; Zeng, Rong; Liu, Changwei

2018-05-01

The objective of this study was to investigate and to compare the early and long-term results of open surgery with endovascular intervention in the treatment of extracranial carotid artery aneurysms (ECCAs). A retrospective review of patients diagnosed with ECCAs who underwent open surgical or endovascular treatment from 1997 to 2017 was performed. Clinical characteristics, aneurysm profile, and treatment outcomes were recorded. Early results (<30 days) were evaluated in terms of mortality, perioperative stroke or transient ischemic attack, and cranial nerve injury. Late results were analyzed in terms of both overall and stroke-free survival and freedom from reinterventions. A total of 48 patients with ECCAs including 34 (70.8%) true aneurysms and 14 (29.2%) pseudoaneurysms were treated. The median age was 51 years, and 19 patients (39.6%) were men; 41 patients (85.4%) had symptoms, whereas 7 (14.6%) were asymptomatic. Among 48 patients, 32 patients (66.7%) underwent open surgery; endovascular repair was performed on 16 patients (33.3%). The 30-day stroke or transient ischemic attack rate was not significantly different between the open group (6.3% [2/32]) and the endovascular group (0% [0/16]; P = .307). Cranial nerve injuries occurred in eight patients in the open group (25%) and in no patient in the endovascular group (0%; P = .029). Median length of stay was significantly longer in the open group than in the endovascular group (20 vs 14 days, respectively; P = .013). Median follow-up was 46 months (range, 0-20 years), and no aneurysm-related death occurred during this period. Overall survival rates at 5 years were 88.7% (standard error [SE], 0.08) in the open group and 91.7% (SE, 0.08) in the endovascular group (P = .319; log-rank, .992). For the same time interval, stroke-free survival rates were 85.2% (SE, 0.10) in the open group and 92.2% (SE, 0.07) in the endovascular group (P = .653; log-rank, .201). One patient (1/28 [3.6%]) in the open group

Safety and efficacy of alternative antibiotic regimens compared with 7 day injectable procaine benzylpenicillin and gentamicin for outpatient treatment of neonates and young infants with clinical signs of severe infection when referral is not possible: a randomised, open-label, equivalence trial.

PubMed

Baqui, Abdullah H; Saha, Samir K; Ahmed, A S M Nawshad Uddin; Shahidullah, Mohammad; Quasem, Iftekhar; Roth, Daniel E; Samsuzzaman, A K M; Ahmed, Wazir; Tabib, S M Shahnawaz Bin; Mitra, Dipak K; Begum, Nazma; Islam, Maksuda; Mahmud, Arif; Rahman, Mohammad Hefzur; Moin, Mamun Ibne; Mullany, Luke C; Cousens, Simon; El Arifeen, Shams; Wall, Stephen; Brandes, Neal; Santosham, Mathuram; Black, Robert E

2015-05-01

Severe infections remain one of the main causes of neonatal deaths worldwide. Possible severe infection is diagnosed in young infants (aged 0-59 days) according to the presence of one or more clinical signs. The recommended treatment is hospital admission with 7-10 days of injectable antibiotic therapy. In low-income and middle-income countries, barriers to hospital care lead to delayed, inadequate, or no treatment for many young infants. We aimed to identify effective alternative antibiotic regimens to expand treatment options for situations where hospital admission is not possible. We did this randomised, open-label, equivalence trial in four urban hospitals and one rural field site in Bangladesh to determine whether two alternative antibiotic regimens with reduced numbers of injectable antibiotics combined with oral antibiotics had similar efficacy and safety to the standard regimen, which was also used as outpatient treatment. We randomly assigned infants who showed at least one clinical sign of severe, but not critical, infection (except fast breathing alone), whose parents refused hospital admission, to one of the three treatment regimens. We stratified randomisation by study site and age (<7 days or 7-59 days) using computer-generated randomisation sequences. The standard treatment was intramuscular procaine benzylpenicillin and gentamicin once per day for 7 days (group A). The alternative regimens were intramuscular gentamicin once per day and oral amoxicillin twice per day for 7 days (group B) or intramuscular procaine benzylpenicillin and gentamicin once per day for 2 days, then oral amoxicillin twice per day for 5 days (group C). The primary outcome was treatment failure within 7 days after enrolment. Assessors of treatment failure were masked to treatment allocation. Primary analysis was per protocol. We used a prespecified similarity margin of 5% to assess equivalence between regimens. This study is registered with ClinicalTrials.gov, number NCT

The beam and detector of the NA62 experiment at CERN

DOE PAGES

Gil, E. Cortina; Albarrán, E. Martín; Minucci, E.; ...

2017-05-31

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K + → π + ν ν¯ decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. Furthermore, the beam line and detector componentsmore » are described together with their early performance obtained from 2014 and 2015 data.« less

The beam and detector of the NA62 experiment at CERN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gil, E. Cortina; Albarrán, E. Martín; Minucci, E.

NA62 is a fixed-target experiment at the CERN SPS dedicated to measurements of rare kaon decays. Such measurements, like the branching fraction of the K + → π + ν ν¯ decay, have the potential to bring significant insights into new physics processes when comparison is made with precise theoretical predictions. For this purpose, innovative techniques have been developed, in particular, in the domain of low-mass tracking devices. Detector construction spanned several years from 2009 to 2014. The collaboration started detector commissioning in 2014 and will collect data until the end of 2018. Furthermore, the beam line and detector componentsmore » are described together with their early performance obtained from 2014 and 2015 data.« less

Unblinded randomized control trial on prophylactic antibiotic use in gustilo II open tibia fractures at Kenyatta National Hospital, Kenya.

PubMed

Ondari, Joshua Nyaribari; Masika, Moses Muia; Ombachi, Richard Bwana; Ating'a, John Ernest

2016-10-01

To determine the difference in infection rate between 24h versus five days of prophylactic antibiotic use in management of Gustilo II open tibia fractures. Unblinded randomized control trial. Accident and Emergency, orthopedic wards and outpatient clinics at Kenyatta National Hospital (KNH). The study involved patients aged 18-80 years admitted through accident and emergency department with Gustilo II traumatic open tibia fractures. Patients were randomized into either 24hour or five day group and antibiotics started for 24hours or five days after surgical debridement. The wounds were exposed and scored using ASEPSIS wound scoring system for infection after 48h, 5days and at 14days. The main outcomes of interest were presence of infection at days 2, 5 and 14 and effect of duration to antibiotic administration on infection rate. There was no significant difference in infection rates between 24-hour and 5-day groups with infection rates of 23% (9/40) vs. 19% (7/37) respectively (p=0.699). The infection rate was significantly associated with time lapsed before administration of antibiotics (p=0.004). In the use of prophylactic antibiotics for the management of Gustilo II traumatic open tibia fractures, there is no difference in infection rate between 24hours and five days regimen but time to antibiotic administration correlates with infection rate. Antibiotic use for 24hours only has proven adequate prophylaxis against infection. This is underlined in our study which we hope shall inform practice in our setting. A larger, more appropriately controlled study would be useful. Copyright © 2016 Elsevier Ltd. All rights reserved.

CERN-derived analysis of lunar radiation backgrounds

NASA Technical Reports Server (NTRS)

Wilson, Thomas L.; Svoboda, Robert

1993-01-01

The Moon produces radiation which background-limits scientific experiments there. Early analyses of these backgrounds have either failed to take into consideration the effect of charm in particle physics (because they pre-dated its discovery), or have used branching ratios which are no longer strictly valid (due to new accelerator data). We are presently investigating an analytical program for deriving muon and neutrino spectra generated by the Moon, converting an existing CERN computer program known as GEANT which does the same for the Earth. In so doing, this will (1) determine an accurate prompt neutrino spectrum produced by the lunar surface; (2) determine the lunar subsurface particle flux; (3) determine the consequence of charm production physics upon the lunar background radiation environment; and (4) provide an analytical tool for the NASA astrophysics community with which to begin an assessment of the Moon as a scientific laboratory versus its particle radiation environment. This will be done on a recurring basis with the latest experimental results of the particle data groups at Earth-based high-energy accelerators, in particular with the latest branching ratios for charmed meson decay. This will be accomplished for the first time as a full 3-dimensional simulation.

[The Big Data Game : On the Ludic Constitution of the Collaborative Production of Knowledge in High-Energy Physics at CERN].

PubMed

Dippel, Anne

2017-12-01

This article looks at how games and play contribute to the big data-driven production of knowledge in High-Energy Physics, with a particular focus on the Large Hadron Collider (LHC) at the European Organization for Nuclear Research (CERN), where the author has been conducting anthropological fieldwork since 2014. The ludic (playful) aspect of knowledge production is analyzed here in three different dimensions: the Symbolic, the Ontological, and the Epistemic. The first one points towards CERN as place where a cosmological game of probability is played with the help of Monte-Carlo simulations. The second one can be seen in the agonistic infrastructures of competing experimental collaborations. The third dimension unfolds in ludic platforms, such as online Challenges and citizen science games, which contribute to the development of machine learning algorithms, whose function is necessary in order to process the huge amount of data gathered from experimental events. Following Clifford Geertz, CERN itself is characterized as a site of deep play, a concept that contributes to understanding wider social and cultural orders through the analysis of ludic collective phenomena. The article also engages with Peter Galison's idea of the trading zone, proposing to comprehend it in the age of big data as a Playground. Thus the author hopes to contribute to a wider discussion in the historiographical and social study of science and technology, as well as in cultural anthropology, by recognizing the ludic in science as a central element of understanding collaborative knowledge production.

DG's New Year's presentation

ScienceCinema

Heuer, R.-D.

2018-05-22

CERN general staff meeting. Looking back at key messages: Highest priority: LHC physics in 2009; Increase diversity of the scientific program; Prepare for future projects; Establish open and direct communication; Prepare CERN towards a global laboratory; Increase consolidation efforts; Financial situation--tight; Knowledge and technology transfer--proactive; Contract policy and internal mobility--lessons learned.

Open Smart Energy Gateway (OpenSEG)

DOE Office of Scientific and Technical Information (OSTI.GOV)

The Open Smart Energy Gateway (OpenSEG) aims to provide near-real time smart meter data to consumers without the delays or latencies associated with it being transported to the utility data center and then back to the consumer's application. To do this, the gateway queries the local Smart Meter to which it is bound to get energy consumption information at pre-defined intervals (minimum interval is 4 seconds). OpenSEG then stores the resulting data internally for retrieval by an external application.

Investigating the Inverse Square Law with the Timepix Hybrid Silicon Pixel Detector: A CERN [at] School Demonstration Experiment

ERIC Educational Resources Information Center

Whyntie, T.; Parker, B.

2013-01-01

The Timepix hybrid silicon pixel detector has been used to investigate the inverse square law of radiation from a point source as a demonstration of the CERN [at] school detector kit capabilities. The experiment described uses a Timepix detector to detect the gamma rays emitted by an [superscript 241]Am radioactive source at a number of different…

Interprofessional education day - an evaluation of an introductory experience for first-year students.

PubMed

Singer, Zachary; Fung, Kevin; Lillie, Elaine; McLeod, Jennifer; Scott, Grace; You, Peng; Helleman, Krista

2018-05-01

Interprofessional health care teams have been shown to improve patient safety and reduce medical errors, among other benefits. Introducing interprofessional concepts to students in full day events is an established model that allows students to learn together. Our group developed an academic day for first-year students devoted to an introductory interprofessional education (IPE) experience, 'IPE Day'. In total, 438 students representing medicine, dentistry, pharmacy and optometry gathered together, along with 25 facilitators, for IPE Day. Following the day's program, students completed the evaluation consisting of the Interprofessional Collaborative Competencies Attainment Survey and open-ended questions. Narrative responses were analyzed for content and coded using the Canadian Interprofessional Health Collaborative competency domains. Three hundred and eight evaluations were completed. Students reported increased self-ratings of competency across all 20 items (p < 0.05). Their comments were organized into the six domains: interprofessional communication, collaborative leadership, role clarification, patient-centred care, conflict resolution, and team functioning. Based on these findings, we suggest that this IPE activity may be useful for improving learner perceptions about their interprofessional collaborative practice competence.

[DL-phenylalanine as an antidepressant. Open study (author's transl)].

PubMed

Beckmann, H; Ludolph, E

1978-01-01

In an open study dl-phenylalanine in doses from 75--200 mg/day was administered to 20 depressed patients for 20 days. At the end of the trial 12 patients (8 with complete, 4 with good response) could be discharged without any further treatment. 4 patients with partially untypical depressions experienced mild to moderate responses, whereas 4 patients did not respond at all to the phenylalanine administration. Depressive "core symptoms" as depressed mood, retardation and/or agitation were preferentially, anxiety and sleep disturbances moderately and hypochondriasis and compulsiveness were not influenced. It is concluded that dl-phenylalanine might have substantial antidepressant properties and that further controlled investigations are justified.

Outcomes of laparoscopic resection of Meckel's diverticulum are equivalent to open laparotomy.

PubMed

Ezekian, Brian; Leraas, Harold J; Englum, Brian R; Gilmore, Brian F; Reed, Christopher; Fitzgerald, Tamara N; Rice, Henry E; Tracy, Elisabeth T

2018-03-15

Meckel's diverticulum (MD) is a common congenital anomaly caused by failure of involution of the omphalomesenteric duct. Enthusiasm for minimally invasive surgery (MIS) in children has burgeoned as technologies have advanced, but the outcomes of laparoscopic resection in comparison to open laparotomy for MD remain poorly defined. We queried a large national database to compare current practice patterns and clinical outcomes between surgical approaches for MD in the pediatric population. The National Surgical Quality Improvement Program-Pediatric (NSQIP-Ped) database was queried for patients undergoing surgical intervention for MD (2011-2014). Patients were stratified by surgical approach. Baseline characteristics, intraoperative variables, and perioperative complications were compared by univariate analysis using Pearson's χ 2 test for categorical variables and Kruskall-Wallis test for continuous variables. Primary outcomes of interest were length of stay (LOS), rate of readmission, and 30-day mortality. Secondary outcomes included operative time, anesthesia time, postoperative complications, and rates of reoperation. A total of 148 cases of MD were identified, of which 73 (49.3%) were initially managed with a laparoscopic approach and 75 (50.7%) were managed with an open approach. We found a high rate of conversion from laparoscopy to an open approach (20/73 or 27.4%). The median age of the laparoscopic group was higher than the open group (8.3 vs. 2.5years, p<0.001). Operative and anesthesia time, LOS, 30-day mortality, post-operative complications, and rates of reoperation and readmission were similar between groups (all p>0.05). Nearly half of all resections for MD in children are now approached laparoscopically. This approach has equivalent outcomes to traditional open laparotomy. More widespread use of a hybrid approach with laparoscopy and exteriorization of the small bowel through an extended port site may facilitate avoiding open laparotomy. Routine

Better value digital health: the medium, the market and the role of openness.

PubMed

Reynolds, Carl J

2013-08-01

The recent NHS 'hack days' have showcased the enthusiasm and talent of the junior doctor body as well as the potential of open source, open governance and small-medium enterprise. There still remains much scope for developing better value digital health services within the NHS. This article sets out the current state of NHS information technology (IT), how it fails to meet the needs of patients and professionals alike and suggests how better value digital health can be achieved.

Infrasonic wave accompanying a crack opening during the 2015 Hakone eruption

NASA Astrophysics Data System (ADS)

Yukutake, Yohei; Ichihara, Mie; Honda, Ryou

2018-03-01

To understand the initial process of the phreatic eruption of the Hakone volcano from June 29 to July 01, 2015, we analyzed infrasound data using the cross-correlation between infrasound and vertical ground velocity and compared the results of our analysis to the crustal deformation detected by tiltmeters and broadband seismometers. An infrasound signal and vertical ground motion due to an infrasound wave coupled to the ground were detected simultaneously with the opening of a crack source beneath the Owakudani geothermal region during the 2-min time period after 07:32 JST on June 29, 2015 (JST = UTC + 8 h). Given that the upper end of the open crack was approximately 150 m beneath the surface, the time for the direct emission of highly pressurized fluid from the upper end of the open crack to the surface should have exceeded the duration of the inflation owing to the hydraulic diffusivity in the porous media. Therefore, the infrasound signal coincident with the opening of the crack may reflect a sudden emission of volcanic gas resulting from the rapid vaporization of pre-existing groundwater beneath Owakudani because of the transfer of the volumetric strain change from the deformation source. We also noticed a correlation pattern corresponding to discrete impulsive infrasound signals during vent formation, which occurred several hours to 2 days after the opening of the crack. In particular, we noted that the sudden emission of vapor coincided with the inflation of the shallow pressure source, whereas the eruptive burst events accompanied by the largest vent formation were delayed by approximately 2 days. Furthermore, we demonstrated that the correlation method is a useful tool in detecting small infrasound signals and provides important information regarding the initial processes of the eruption.[Figure not available: see fulltext.

The experience of a good day: a phenomenological study to explain a good day as experienced by a newly qualified RN.

PubMed

Jackson, Carole

2005-04-01

The main aim of this study was to provide an explanation of the newly qualified nurse's experience and description of a good day. Secondly, it sought to provide an explanation of how a good day made them feel about nursing. By identifying the main components of a good day and what positively effects the experience of a working day for a newly qualified nurse, it may be possible to move towards an increase in the occurrence of the components and emulation of a good day. While there is evidence to suggest that positive experiences within nursing increase job satisfaction and aid retention to the profession, the experience of a good day and what constitutes a good day for a newly qualified nurse has not been explored. The main components of a good day have not been identified and no work has been carried out to ascertain how these days make nurses feel about their chosen career. The aims of the study lent themselves to a phenomenological descriptive approach to research, the objective of which is identification of the essence of behaviour. Eight newly qualified nurses agreed to take part in the research. Each participant was interviewed twice, and in addition one group interview was arranged to clarify themes. The interviews, which were audio taped, were informal allowing the participants to answer in an open and unstructured manner. Once completed, all the tapes were transcribed and immersion and analysis of the data led to 5 themes naturally emerging as the components of a good day. The identified themes were, doing something well, good relationships with patients, feeling that you've achieved something, getting the work done and you need team work. In addition, although not a theme of a good day but of great importance was the description of 'that wonderful feeling at the end of a good day'. These themes contributed to feelings of job satisfaction and the pleasure of nursing. More specifically the concept of knowing the patient both from a personal level and

Full-Day or Half-Day Kindergarten? ERIC Digest.

ERIC Educational Resources Information Center

Rothenberg, Dianne

This ERIC Digest examines how changing family patterns have affected the full-day/half-day kindergarten issue, discussing why schools are currently considering alternative scheduling and describing the advantages and disadvantages of each type of program. The following changing family patterns affecting the choice of full-day kindergarten programs…

Recent developments from the OPEnS Lab

NASA Astrophysics Data System (ADS)

Selker, J. S.; Good, S. P.; Higgins, C. W.; Sayde, C.; Buskirk, B.; Lopez, M.; Nelke, M.; Udell, C.

2016-12-01

The Openly Published Environmental Sensing (OPEnS) lab is a facility that is open to all from around the world to use (http://agsci.oregonstate.edu/open-sensing). With 3-D CAD, electronics benches, 3-D printers and laser cutters, and a complete precision metal shop, the lab can build just about anything. Electronic platforms such as the Arduino are combined with cutting edge sensors, and packaged in rugged housing to address critical environmental sensing needs. The results are published in GITHub and in the AGU journal Earth and Space Sciences under the special theme of "Environmental Sensing." In this poster we present advancements including: A ultra-precise isotopic sampler for rainfall; an isotopic sampler for soil gas; a data-logging wind vane that can be mounted on the tether of a balloon; a rain-gage calibrator with three rates of constant application; a <$20 dissolved O2 probe for water; a stream-bed permeameter that gives rapid quantification of permeability. You can use the OPEnS lab! Just sketch your idea on a white board and send it in. The conversation is started, and your prototype can be ready in a few weeks. We have a staff of three engineers ready to help, where you are working remotely, or decide to spend some time with the team in Corvallis.

Leaf Starch Turnover Occurs in Long Days and in Falling Light at the End of the Day1[OPEN

PubMed Central

Mengin, Virginie; Arrivault, Stéphanie

2017-01-01

We investigated whether starch degradation occurs at the same time as starch synthesis in Arabidopsis (Arabidopsis thaliana) leaves in the light. Starch accumulated in a linear fashion for about 12 h after dawn, then accumulation slowed and content plateaued. Following decreases in light intensity, the rate of accumulation of starch declined in proportion to the decline in photosynthesis if the decrease occurred <10 h after dawn, but accumulation ceased or loss of starch occurred if the same decrease in light intensity was imposed more than 10 h after dawn. These changes in starch accumulation patterns after prolonged periods in the light occurred at both high and low starch contents and were not related to time-dependent changes in either the rate of photosynthesis or the partitioning of assimilate between starch and Suc, as assessed from metabolite measurements and 14CO2 pulse experiments. Instead, measurements of incorporation of 13C from 13CO2 into starch and of levels of the starch degradation product maltose showed that substantial starch degradation occurred simultaneously with synthesis at time points >14 h after dawn and in response to decreases in light intensity that occurred >10 h after dawn. Starch measurements in circadian clock mutants suggested that the clock influences the timing of onset of degradation. We conclude that the propensity for leaf starch to be degraded increases with time after dawn. The importance of this phenomenon for efficient use of carbon for growth in long days and for prevention of starvation during twilight is discussed. PMID:28663333

Local anesthetic infusion pump for pain management following open inguinal hernia repair: a meta-analysis.

PubMed

Wu, Chien-Chih; Bai, Chyi-Huey; Huang, Ming-Te; Wu, Chih-Hsiung; Tam, Ka-Wai

2014-01-01

Open inguinal hernia repair is one of the most painful procedures in day surgery. A continuous ambulatory analgesic is thought to reduce postoperative pain when it is applied to the surgical site. The aim of this study is to evaluate the efficacy of local anesthetic infusion pump following open inguinal hernia repair for the reduction of postoperative pain. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) that have investigated the outcomes of using an infusion pump for delivering a local anesthetic contrasted to a control group for open inguinal hernia repair. Pain was assessed from Day 1 to Day 5 following the surgery. The secondary outcomes included analgesia use and postoperative complications. We reviewed 5 trials that totaled 288 patients. The analgesic effects of bupivacaine (4 trials) and ropivacaine (one trial) were compared with a placebo group. The pooled mean difference in the score measuring the degree of pain diminished significantly at Day 1 to Day 4 in the experimental group. Two studies have reported that the number of analgesics required also decreased in the experimental group. No bupivacaine-related complication was reported. Our results revealed that applying a local anesthetic infusion pump following inguinal hernia repairs was more efficacious for reducing postoperative pain than a placebo. However, the findings were based on a small body of evidence in which methodological quality was not high. The potential benefits of applying a local anesthetic infusion pump to hernia repair must still be adequately investigated using further RCTs. Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

[A new method of endoscopic harvesting of the great saphenous vein in an open system].

PubMed

Vecherskiĭ, Iu Iu; Zatolokin, V V; Petlin, K A; Akhmedov, Sh D; Shipulin, V M

We examined a total of 246 patients subjected to coronary artery bypass grafting with the use of the great saphenous vein (GSV). The patients were subdivided into two groups. Group One (n=121) patients endured procurement of the great saphenous vein by a new endoscopic technique in an open system with the help of the equipment Karl Storz and electric dissector Ligasure. In Group Two (n=125) patients the vein was harvested by means of the traditional open method. In all patients we evaluated complications in the early postoperative period 13±2.5 days after the operation. The rate of relapsing angina pectoris in both Groups turned out to be low and did not differ (1.65% in Group One and 1.6% in Group Two). Patients of the both groups differed significantly by the incidence of postoperative complications on the lower limbs in the zone of procurement of the GSV (9.09% in Group One and 26.4% in Group Two, p=0.131). Group Two patients (open method of procurement of the GSV) were considerably more often found to have developed cases of lymphorrhoea, haematomas, disjunction of the sutures (21.6%) compared with Group One (endoscopic method) patients (3.3%) (p=0.167), which in 10.4% of cases required secondary surgical debridement of wounds in patients after the open harvest of the GSV. Eventually, the length of hospital stay for Group Two patients increased significantly (15 ± 4.5 days) compared with Group One patients (8±1.1 days) (p=0.361). Hence, the endoscopic method of harvesting the GSV in the open CO2 system makes it possible to obtain a good cosmetic effect on the lower limbs after the operation, to considerably decrease the complications rate, thus reducing the length of hospital stay.

Cancel the Cardinals Home Opener?! Lessons in Melting and Evaporation

ERIC Educational Resources Information Center

Market, Patrick S.

2005-01-01

The St. Louis Cardinals are scheduled to play their home opener the next day and Megan Riley, a young meteorologist who works for a private weather consulting firm, is responsible for developing the weather forecast. It's looking like she may need to change her prediction from rain to snow. In this interrupted case study, students work in small…

Gallbladder removal - open

MedlinePlus

Cholecystectomy - open; Gallbladder - open cholecystectomy; Cholecystitis - open cholecystectomy; Gallstones - open cholecystectomy ... a medical instrument called a laparoscope ( laparoscopic ... Open gallbladder surgery is used when laparoscopic surgery cannot ...

Big Bang Day : The Great Big Particle Adventure - 2. Who Ordered That?

ScienceCinema

None

2017-12-09

In this series, comedian and physicist Ben Miller asks the CERN scientists what they hope to find. The atoms that make up our material world are important to us, but it turns out they aren't so significant on the cosmic stage. In fact early in the search for the stuff of atoms, researchers discovered particles that played no part in Earthly chemistry - for example particles in cosmic rays that resemble electrons (the stuff of electricity and the chemical glue in molecules) in almost all respects except that they weigh 140 times more. "Who ordered that?" one Nobel laureate demanded. They also discovered antimatter - the destructive mirror-image particles at obliterate all matter they come into contact with. In fact, the Universe is mostly made up of particles that could never make atoms, so that we are just the flotsam of the cosmos. But the main constituent of the Universe, what makes 80% of creation, has never been seen in the lab. Researchers at CERN believe they can create samples of it, down here on Earth.

Expectancy of an open-book test decreases performance on a delayed closed-book test.

PubMed

Agarwal, Pooja K; Roediger, Henry L

2011-11-01

Two experiments examined the influence of practice with, and the expectancy of, open-book tests (students viewed studied material while taking the test) versus closed-book tests (students completed the test without viewing the studied material) on delayed retention and transfer. Using GRE materials specifically designed for open-book testing, participants studied passages and then took initial open- or closed-book tests. Open-book testing led to better initial performance than closed-book testing, but on a delayed criterial (closed-book) test both types of testing produced similar retention after a two-day delay in Experiment 1. In Experiment 2 participants were informed in advance about the type of delayed criterial test to expect (open- or closed-book). Expecting an open-book test (relative to a closed-book test) decreased participants' time spent studying and their delayed test performance on closed-book comprehension and transfer tests, demonstrating that test expectancy can influence long-term learning. Expectancy of open-book tests may impair long-term retention and transfer compared to closed-book tests, despite superior initial performance on open-book tests and students' preference for open-book tests.

[The use of open source software in graphic anatomic reconstructions and in biomechanic simulations].

PubMed

Ciobanu, O

2009-01-01

The objective of this study was to obtain three-dimensional (3D) images and to perform biomechanical simulations starting from DICOM images obtained by computed tomography (CT). Open source software were used to prepare digitized 2D images of tissue sections and to create 3D reconstruction from the segmented structures. Finally, 3D images were used in open source software in order to perform biomechanic simulations. This study demonstrates the applicability and feasibility of open source software developed in our days for the 3D reconstruction and biomechanic simulation. The use of open source software may improve the efficiency of investments in imaging technologies and in CAD/CAM technologies for implants and prosthesis fabrication which need expensive specialized software.

Day-case surgery for total hip and knee replacement: How safe and effective is it?

PubMed

Lazic, Stefan; Boughton, Oliver; Kellett, Catherine F; Kader, Deiary F; Villet, Loïc; Rivière, Charles

2018-04-01

Multimodal protocols for pain control, blood loss management and thromboprophylaxis have been shown to benefit patients by being more effective and as safe (fewer iatrogenic complications) as conventional protocols.Proper patient selection and education, multimodal protocols and a well-defined clinical pathway are all key for successful day-case arthroplasty.By potentially being more effective, cheaper than and as safe as inpatient arthroplasty, day-case arthroplasty might be beneficial for patients and healthcare systems. Cite this article: EFORT Open Rev 2018;3:130-135. DOI: 10.1302/2058-5241.3.170031.

KTAG: The Kaon Identification Detector for CERN experiment NA62

NASA Astrophysics Data System (ADS)

Fry, J. R.; CERN NA62 Collaboration

2016-07-01

In the study of ultra-rare kaon decays, CERN experiment NA62 exploits an unseparated monochromatic (75 GeV/c) beam of charged particles of flux 800 MHz, of which 50 MHz are K+. Kaons are identified with more than 95% efficiency, a time resolution of better than 100 ps, and misidentification of less than 10-4 using KTAG, a differential, ring-focussed, Cherenkov detector. KTAG utilises 8 sets of 48 Hamamatsu PMTs, of which 32 are of type 9880 and 16 of type 7400, with signals fed directly to the differential inputs of NINO front-end boards and then to TDC cards within the TEL62 system. Leading and trailing edges of the PMT signal are digitised, enabling slewing corrections to be made, and a mean hit rate of 5 MHz per PMT is supported. The electronics is housed within a cooled and insulated Faraday cage with environmental monitoring capabilities.

"The Open Library at AU" (Athabasca University): Supporting Open Access and Open Educational Resources

ERIC Educational Resources Information Center

Elliott, Colin; Fabbro, Elaine

2015-01-01

To address challenges that learners, course creators, librarians and academics involved with OER and MOOCs are facing when looking for scholarly materials, Athabasca University Library has initiated the development of "the Open Library at AU." This open library is a full library website that provides easy access to open and free…

OpenMx: An Open Source Extended Structural Equation Modeling Framework

ERIC Educational Resources Information Center

Boker, Steven; Neale, Michael; Maes, Hermine; Wilde, Michael; Spiegel, Michael; Brick, Timothy; Spies, Jeffrey; Estabrook, Ryne; Kenny, Sarah; Bates, Timothy; Mehta, Paras; Fox, John

2011-01-01

OpenMx is free, full-featured, open source, structural equation modeling (SEM) software. OpenMx runs within the "R" statistical programming environment on Windows, Mac OS-X, and Linux computers. The rationale for developing OpenMx is discussed along with the philosophy behind the user interface. The OpenMx data structures are…

Endovascular repair or open repair for ruptured abdominal aortic aneurysm: a Cochrane systematic review

PubMed Central

Badger, S A; Harkin, D W; Blair, P H; Ellis, P K; Kee, F; Forster, R

2016-01-01

Objectives Emergency endovascular aneurysm repair (eEVAR) may improve outcomes for patients with ruptured abdominal aortic aneurysm (RAAA). The study aim was to compare the outcomes for eEVAR with conventional open surgical repair for the treatment of RAAA. Setting A systematic review of relevant publications was performed. Randomised controlled trials (RCTs) comparing eEVAR with open surgical repair for RAAA were included. Participants 3 RCTs were included, with a total of 761 patients with RAAA. Interventions Meta-analysis was performed with fixed-effects models with ORs and 95% CIs for dichotomous data and mean differences with 95% CIs for continuous data. Primary and secondary outcome measures Primary outcome was short-term mortality. Secondary outcome measures included aneurysm-specific and general complication rates, quality of life and economic analysis. Results Overall risk of bias was low. There was no difference between the 2 interventions on 30-day (or in-hospital) mortality, OR 0.91 (95% CI 0.67 to 1.22; p=0.52). 30-day complications included myocardial infarction, stroke, composite cardiac complications, renal complications, severe bowel ischaemia, spinal cord ischaemia, reoperation, amputation and respiratory failure. Reporting was incomplete, and no robust conclusion was drawn. For complication outcomes that did include at least 2 studies in the meta-analysis, there was no clear evidence to support a difference between eEVAR and open repair. Longer term outcomes and cost per patient were evaluated in only a single study, thus precluding definite conclusions. Conclusions Outcomes between eEVAR and open repair, specifically 30-day mortality, are similar. However, further high-quality trials are required, as the paucity of data currently limits the conclusions. PMID:26873043

Content and evolution of potential furfural compounds in commercial milk-based infant formula powder after opening the packet.

PubMed

Chávez-Servín, Jorge L; de la Torre Carbot, Karina; García-Gasca, Teresa; Castellote, Ana I; López-Sabater, M Carmen

2015-01-01

Potential furfural compounds were examined by RP-HPLC-DAD in 20 commercial milk-based powdered infant formula (IF) brands from local markets from Paris, France; DF, Mexico; Copenhagen, Denmark; England, UK; and Barcelona, Spain. We traced the evolution of these compounds after the packets had been opened at 0, 30 and 70 days of storage at room temperature (≈25 °C; minimum 23 °C and maximum 25.5 °C). All formula brands were analysed during the first 3-5 months of their shelf life. The mean values of all IFs for potential 5-hydroxymethyl-2-furaldehyde (HMF)+2-furaldehyde (F) were 1115.2 μg/100 g (just opened), 1157.6 μg/100 g (30 days) and 1344.5 μg/100 g of product (70 days). In general, slight increases of potential furfural contents were observed in most of the studied IFs, which suggests that the Maillard reaction increases after opening the packets. The main furfural compound found was HMF, as expected. The range of potential HMF consumed for an infant about 6 months old feeding only on formula was estimated between 0.63 mg and 3.25 mg per day. Copyright © 2014 Elsevier Ltd. All rights reserved.

A Study of Learners Perception and Attitude towards BA/BSS Program of SSHL of Bangladesh Open University